Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AADACL2 MGC72001 ENSG00000197953 "Arylacetamide deacetylase like 2" Q6P093 3 151733916-151761339 "Predicted secreted proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "skin 1: 35.6" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 30.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.20e-2)" "unprognostic (3.10e-3)" "unprognostic (2.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (3.00e-1)" "unprognostic (2.91e-4)" 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 35.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 30.7 0.1 0.1 0.0 0.0 0.0 AAMDC "C11orf67, CK067, FLJ21035, PTD015" ENSG00000087884 "Adipogenesis associated Mth938 domain containing" Q9H7C9 11 77821109-77918432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 656.7" "Cell type enhanced" "Detected in all" "Theca cells: 385.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 143.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 280.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA037918, HPA037919" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA037918: AB_2675737, HPA037919: AB_2675738" "unprognostic (3.10e-2)" "unprognostic (9.04e-3)" "unprognostic (6.02e-2)" "unprognostic (4.67e-1)" "unprognostic (1.27e-1)" "unprognostic (3.51e-2)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.07e-2)" "unprognostic (1.23e-1)" "unprognostic (7.08e-2)" "unprognostic (1.90e-1)" "unprognostic (2.08e-1)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "unprognostic (3.84e-2)" 75.8 180.9 30.1 13.0 35.8 21.0 62.5 35.2 42.6 51.0 31.4 66.6 37.4 41.4 27.9 24.6 47.5 23.4 178.9 30.5 31.7 56.0 57.9 46.9 13.8 37.2 34.4 56.7 34.4 27.4 28.6 21.7 35.9 46.0 29.2 20.1 36.6 34.6 656.7 55.4 47.5 40.2 31.9 31.7 62.4 42.2 34.3 23.7 42.2 173.0 13.6 48.1 42.7 42.7 30.3 24.3 37.2 26.5 106.0 73.3 10.0 49.2 33.4 43.8 54.1 280.1 44.6 20.3 46.5 83.0 43.2 16.9 56.4 32.9 51.9 47.1 45.3 19.5 43.5 52.4 52.2 11.2 17.1 98.3 22.2 46.0 24.2 40.2 131.3 27.0 23.1 32.0 93.2 35.6 23.8 44.3 17.3 84.5 41.4 22.3 63.6 19.6 58.2 18.1 13.1 49.2 62.4 26.7 36.0 55.1 41.2 21.1 138.2 45.5 24.7 87.5 16.5 34.2 58.4 37.8 17.7 18.0 26.2 143.1 28.9 33.3 14.6 17.7 18.8 18.3 28.4 24.2 32.6 25.2 24.8 18.4 16.9 35.9 17.5 33.8 47.3 16.3 30.1 35.8 35.2 42.6 30.5 31.7 37.2 34.4 35.9 31.9 34.3 42.7 68.4 83.3 25.4 19.6 10.0 64.2 82.7 51.0 24.5 10.0 58.7 67.2 114.1 62.9 42.5 79.1 4.2 29.1 11.8 70.2 144.8 60.0 100.1 37.7 27.8 55.7 22.7 19.1 6.9 73.1 43.1 64.5 39.3 35.8 41.2 53.4 93.9 122.2 46.9 11.8 8.9 48.7 44.7 29.9 35.9 36.3 68.3 22.5 83.6 8.4 56.2 101.3 16.5 18.1 24.8 70.2 132.2 64.3 10.2 46.6 160.3 200.8 50.1 13.9 46.0 53.5 65.8 154.0 85.4 29.2 100.7 15.7 14.8 385.5 61.0 71.2 AARD "C8orf85, LOC441376" ENSG00000205002 "Alanine and arginine rich domain containing protein" Q4LEZ3 8 116938207-116944487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.5;urinary bladder: 7.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 27.6;Breast glandular cells: 26.0;Breast myoepithelial cells: 29.0;granulocytes: 14.5;Late spermatids: 18.4;Proximal tubular cells: 14.9;Spermatocytes: 57.4" "Cancer enriched" "Detected in many" 8 "breast cancer: 27.0" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 21.7;JURKAT: 7.2;SK-BR-3: 11.8;U-2 OS: 5.5;U-266/84: 4.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 4 "midbrain: 4.4" HPA068290 Approved "Lipid droplets" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Lipid droplets" "HPA068290: " "unprognostic (5.81e-2)" "unprognostic (2.28e-1)" "unprognostic (1.32e-1)" "unprognostic (7.28e-8)" "unprognostic (3.42e-2)" "unprognostic (4.32e-3)" "unprognostic (4.34e-2)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (8.29e-2)" "unprognostic (8.57e-3)" "unprognostic (4.20e-1)" "unprognostic (2.23e-6)" "unprognostic (1.67e-1)" "unprognostic (9.78e-3)" "unprognostic (3.77e-2)" "unprognostic (5.27e-4)" 0.6 0.9 0.5 0.4 0.8 0.2 4.3 0.4 0.9 0.3 0.9 5.9 0.1 0.8 0.2 2.4 0.1 0.2 0.0 0.6 0.6 1.0 0.0 2.5 0.8 1.2 1.0 0.0 0.0 0.0 0.0 0.4 0.9 0.6 0.5 0.1 2.0 0.1 0.1 1.5 1.0 1.0 0.8 0.1 6.8 22.5 0.7 0.0 0.1 0.0 0.4 7.7 0.2 1.3 0.0 0.0 0.5 0.0 0.0 0.0 0.2 1.8 0.3 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.5 0.0 0.2 0.1 2.4 0.0 0.2 0.4 0.0 0.1 0.1 0.1 0.0 7.2 0.0 2.4 0.1 0.5 0.9 0.1 1.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 1.9 0.3 0.0 11.8 0.1 0.2 0.5 0.0 0.0 0.1 5.5 0.2 0.0 1.6 4.5 0.0 3.0 0.0 0.3 1.2 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.7 0.3 0.1 0.2 0.6 0.0 0.5 0.8 0.4 0.9 0.6 0.6 1.2 1.0 0.9 0.8 0.7 1.3 0.2 12.8 27.6 0.0 0.1 0.8 0.6 0.2 0.0 0.4 26.0 29.0 0.9 0.0 5.0 7.3 0.0 0.2 0.8 0.1 1.9 0.1 9.3 0.1 1.7 0.9 0.0 0.0 0.8 0.0 0.9 1.4 0.0 0.0 14.5 0.1 0.0 0.1 0.0 1.7 2.1 0.0 0.0 0.0 0.3 18.4 4.1 0.5 0.0 0.0 0.1 0.1 4.1 0.0 0.2 0.1 0.0 0.7 0.0 0.6 0.0 14.9 0.7 0.2 0.0 0.5 1.1 57.4 7.3 0.0 0.6 0.3 0.8 2.0 0.0 0.4 ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 12.9;Suprabasal keratinocytes: 38.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "hTCEpi: 38.7;SK-BR-3: 18.3;T-47d: 9.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 5.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.3 0.2 0.2 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 2.8 0.3 3.9 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 38.7 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.5 0.1 2.7 0.0 18.3 0.0 0.2 9.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 12.9 0.9 6.0 0.0 0.2 1.0 0.5 0.5 0.0 5.1 0.0 0.0 1.1 0.0 3.0 0.0 0.1 2.2 2.6 0.3 0.1 0.0 0.0 1.4 0.0 2.7 0.1 1.5 3.7 0.0 0.5 0.0 0.0 0.4 1.7 2.9 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.6 1.9 0.0 0.7 0.0 1.0 0.0 0.1 3.1 0.2 0.0 0.0 0.2 0.7 0.4 2.2 38.6 3.4 0.0 0.1 0.9 2.7 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ABCC12 MRP9 ENSG00000140798 "ATP binding cassette subfamily C member 12" Q96J65 16 48081006-48156018 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.9" "Group enriched" "Detected in some" 4 "Early spermatids: 4.4;Excitatory neurons: 5.1;Late spermatids: 2.2;Spermatocytes: 6.0;Theca cells: 3.1" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA043100 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA043100: AB_10794922" "unprognostic (1.53e-1)" "unprognostic (6.87e-2)" "unprognostic (2.37e-2)" "unprognostic (4.62e-3)" "unprognostic (1.88e-1)" "unprognostic (1.59e-2)" "unprognostic (2.65e-1)" "unprognostic (7.53e-2)" "unprognostic (4.23e-1)" 0.0 0.0 0.3 0.0 0.3 0.0 0.3 0.3 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.4 0.4 0.2 0.2 0.2 0.2 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.0 0.9 0.0 0.0 0.0 0.0 3.1 0.0 0.0 ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 31.5;Distal tubular cells: 45.0;Hepatocytes: 77.9;Proximal enterocytes: 33.7;Proximal tubular cells: 151.1" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 7 "monocytes: 3.4" "Cell line enriched" "Detected in some" 8 "Hep G2: 68.4" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" 5.6 3.6 0.7 0.3 0.7 0.7 3.8 0.7 1.1 1.0 0.8 5.7 13.2 0.3 0.6 0.3 1.5 2.9 2.6 0.7 0.7 27.4 134.2 7.4 0.0 0.8 0.9 1.0 17.2 2.1 0.9 0.2 0.8 2.9 2.8 0.3 12.7 1.0 4.6 0.4 7.9 0.3 0.7 0.7 6.4 0.4 0.8 0.0 5.6 0.1 0.0 0.4 0.7 0.7 0.0 1.5 0.7 0.0 0.0 0.8 1.8 0.0 0.4 1.0 1.6 7.1 2.3 0.0 0.8 0.0 0.2 0.0 0.7 0.1 0.6 0.0 0.7 1.8 0.2 68.4 0.4 0.0 0.0 2.7 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.0 2.3 0.0 0.1 1.0 0.0 0.8 0.1 0.3 8.4 5.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.7 0.7 0.7 1.1 0.7 0.7 0.8 0.9 0.8 0.7 0.8 0.7 0.3 28.9 31.5 2.9 1.9 0.1 0.5 3.2 0.0 1.0 4.3 3.6 3.3 18.6 8.7 9.2 0.0 0.0 0.0 13.7 45.0 2.2 0.5 4.8 1.0 0.8 3.0 2.7 1.0 7.9 0.0 1.7 13.3 1.0 1.3 1.9 1.8 77.9 1.0 0.0 1.1 10.9 0.0 3.5 0.0 0.7 1.5 1.8 1.8 3.7 3.1 1.5 0.0 1.0 0.4 2.2 8.1 5.7 0.3 2.0 33.7 151.1 25.4 0.6 0.0 0.3 1.2 0.4 0.3 0.2 0.9 0.0 1.4 1.8 11.9 0.7 ABRACL "C6orf115, Costars, HSPC280, PRO2013" ENSG00000146386 "ABRA C-terminal like" Q9P1F3 6 139028745-139043302 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 440.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 501.5;NB-4: 530.8;U-937: 515.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030217 Enhanced Approved Nucleoplasm,Cytosol NA NA 9200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA030217: AB_10602335" "unprognostic (1.10e-2)" "unprognostic (1.63e-1)" "unprognostic (9.30e-2)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (1.72e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.50e-1)" "unprognostic (2.21e-1)" "unprognostic (8.17e-2)" "unprognostic (2.16e-1)" "unprognostic (3.07e-3)" "unprognostic (5.90e-3)" "unprognostic (3.63e-2)" "unprognostic (3.29e-2)" "prognostic favorable (1.65e-6)" 20.1 9.6 16.8 73.7 16.2 87.7 44.9 13.5 20.8 20.7 14.7 95.0 74.1 22.0 136.0 42.0 12.4 36.0 13.3 18.6 15.7 50.0 60.7 31.2 123.1 14.7 14.6 4.1 16.1 49.1 14.4 29.1 16.2 16.3 86.5 5.4 40.8 12.2 3.0 38.8 74.4 23.5 14.9 73.9 34.4 32.3 16.4 139.6 42.4 7.5 87.9 79.6 17.1 16.0 76.8 40.7 100.7 94.8 39.7 62.2 110.6 59.7 42.9 44.5 91.2 91.2 87.4 0.4 105.8 59.8 189.5 112.9 90.4 130.0 51.9 204.4 167.4 297.8 20.7 31.6 57.6 501.5 130.5 55.9 108.2 59.9 49.1 79.4 237.5 204.9 38.4 100.4 129.5 162.7 314.2 530.8 120.9 119.1 78.5 199.8 62.3 23.8 121.7 225.0 225.4 24.8 40.5 112.3 194.5 141.9 45.1 369.8 175.7 28.2 24.0 58.9 107.7 54.1 169.2 20.9 35.7 515.5 84.2 232.3 178.0 114.2 161.1 334.3 252.2 93.8 259.3 208.2 193.9 96.9 250.9 235.9 48.8 152.1 514.5 215.9 260.2 347.8 16.8 16.2 13.5 20.8 18.6 15.7 14.7 14.6 16.2 14.9 16.4 16.0 54.2 19.2 22.2 2.0 87.1 139.6 71.4 195.2 108.1 0.3 86.6 67.8 3.8 27.1 126.2 44.1 0.0 77.1 151.3 304.5 60.7 145.3 4.8 85.8 20.1 55.0 43.1 75.7 12.8 145.0 207.7 23.5 55.5 129.0 79.4 59.9 53.6 254.3 353.1 0.0 9.1 116.8 162.8 286.1 133.9 13.7 4.7 187.6 87.2 5.6 167.9 49.8 189.5 1.0 1.0 167.4 250.6 12.8 121.0 47.9 247.5 440.3 74.1 1.3 32.9 7.2 37.3 3.6 7.7 116.6 90.1 48.6 198.5 17.7 123.6 133.8 ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 331.1;Hepatocytes: 810.5;Proximal tubular cells: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 126.3 74.2 56.9 44.4 64.9 32.5 79.1 63.7 63.9 24.9 68.4 168.7 170.0 29.0 29.8 30.3 24.4 46.9 223.7 53.2 59.8 378.2 1011.9 48.9 36.6 65.1 61.4 34.8 54.1 35.1 34.9 29.6 64.0 26.4 109.6 31.9 20.3 34.0 165.3 28.0 165.2 44.5 62.8 33.6 37.4 37.7 64.3 39.9 55.8 236.6 31.9 41.6 28.6 64.2 3.9 70.5 110.0 97.5 129.9 69.5 57.4 35.2 52.4 53.6 41.2 146.3 58.9 61.1 73.5 117.5 56.7 4.8 176.8 21.0 51.4 190.5 50.4 45.5 79.0 171.4 62.5 0.7 78.3 91.7 6.7 84.8 26.2 44.6 90.0 87.7 42.5 54.7 147.5 81.8 2.7 89.7 101.5 24.8 26.7 150.8 233.0 217.6 177.7 2.8 163.4 130.9 2.7 76.2 5.6 82.1 45.7 60.0 48.1 49.8 60.5 67.8 36.4 112.3 139.7 157.3 35.0 85.7 47.1 53.0 87.4 96.1 99.2 106.5 123.0 43.2 58.3 88.7 103.2 36.3 50.2 73.2 8.3 120.0 108.1 50.1 76.4 112.7 56.9 64.9 63.7 63.9 53.2 59.8 65.1 61.4 64.0 62.8 64.3 64.2 28.4 38.5 47.3 11.8 31.4 3.6 14.2 15.5 11.4 6.7 25.0 25.5 189.9 234.4 23.7 55.2 4.2 36.5 48.2 331.1 295.4 148.5 71.2 7.9 33.9 30.0 40.1 53.6 1.7 45.7 56.0 47.3 23.9 7.7 45.1 63.3 41.4 810.5 109.6 1.7 4.6 73.0 24.4 64.8 18.5 153.9 48.1 50.6 19.6 13.1 57.2 62.2 106.1 4.5 8.7 101.8 161.2 37.2 41.2 9.8 226.6 708.0 26.4 29.5 19.7 42.1 34.9 51.1 42.7 11.1 4.8 27.0 52.2 93.0 144.8 9.6 ACAD9 "MGC14452, NPD002" ENSG00000177646 "Acyl-CoA dehydrogenase family member 9" Q9H845 3 128879596-128924003 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037716, HPA046720" Supported Enhanced Mitochondria No No "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA037716: AB_10673638, HPA046720: AB_2679773" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.61e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.67e-6)" "unprognostic (1.30e-1)" "unprognostic (3.74e-1)" "unprognostic (3.25e-2)" "unprognostic (1.37e-1)" "unprognostic (6.96e-3)" "prognostic favorable (4.32e-8)" "unprognostic (1.52e-1)" "unprognostic (2.64e-2)" "unprognostic (6.56e-2)" "unprognostic (9.96e-2)" 16.7 20.5 9.0 6.1 8.5 4.7 14.5 9.6 10.2 14.4 9.1 13.6 9.0 14.6 7.7 23.2 12.9 7.3 21.9 8.3 8.7 15.6 20.6 11.0 6.6 8.2 8.7 12.9 14.4 27.7 14.6 8.4 8.4 12.1 9.4 4.1 14.2 12.0 30.4 48.0 11.2 11.1 7.4 12.2 15.9 12.5 8.7 12.1 13.6 28.7 11.2 12.9 14.5 9.0 46.2 22.6 18.0 12.6 28.7 20.7 17.5 22.4 26.2 43.6 36.8 33.3 27.1 33.3 21.1 29.5 29.0 35.5 33.8 45.9 32.8 21.2 23.1 29.3 46.8 24.4 21.6 23.9 10.6 22.5 16.8 23.6 26.7 25.1 35.8 25.2 14.4 11.4 29.5 46.5 36.7 19.0 9.9 49.3 33.8 25.5 17.4 35.1 30.9 25.1 19.0 11.6 37.0 32.9 23.2 17.4 44.5 54.8 18.2 13.2 13.4 14.2 20.3 14.5 5.8 28.3 28.3 21.4 22.7 2.4 15.1 4.9 8.3 18.3 7.8 8.1 7.6 7.3 17.5 5.4 6.2 8.0 0.7 6.8 25.2 9.9 8.3 12.1 9.0 8.5 9.6 10.2 8.3 8.7 8.2 8.7 8.4 7.4 8.7 9.0 10.4 16.0 21.7 13.1 9.3 6.2 11.4 16.7 8.6 14.1 11.9 9.5 30.5 15.7 14.8 14.7 10.4 26.2 10.5 11.7 21.5 20.6 20.2 10.4 11.5 11.2 5.4 14.3 14.3 17.8 18.8 12.9 16.8 12.9 16.5 12.0 15.7 26.7 31.5 10.1 17.7 7.4 16.2 9.5 4.0 17.3 10.2 10.8 16.0 7.5 13.4 15.0 12.3 6.0 12.2 14.1 8.7 14.7 9.5 8.1 9.4 26.3 12.0 11.9 13.1 12.7 14.9 22.6 9.6 13.5 14.2 30.6 8.2 18.1 14.3 8.4 ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 3430.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.3;HDLM-2: 31.0;JURKAT: 42.4;Karpas-707: 29.4;NB-4: 37.9;U-937: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Approved "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" 5.6 1.1 0.4 18.9 0.5 41.0 2.1 0.5 0.8 2.3 0.5 7.4 4.1 1.5 0.3 4.2 4.0 3.6 2.1 0.3 0.4 4.6 5.2 16.1 39.5 0.6 0.5 0.9 1.2 0.1 1.3 0.5 0.6 3.8 2.1 0.2 3.6 0.4 0.9 2.5 43.3 0.9 0.5 96.0 5.0 0.8 0.8 25.8 5.2 0.8 22.6 4.3 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.0 23.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 8.8 0.1 0.0 0.1 11.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 42.4 0.0 29.4 0.0 0.0 14.5 37.9 0.4 0.0 0.0 15.1 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.0 0.1 0.0 0.0 9.1 8.2 10.9 0.1 24.9 0.0 28.8 7.9 30.8 29.6 2.4 33.3 20.2 31.5 32.1 13.7 21.3 26.7 27.5 22.6 32.5 0.4 17.3 39.0 22.3 0.4 0.5 0.5 0.8 0.3 0.4 0.6 0.5 0.6 0.5 0.8 0.6 3.8 9.6 5.5 1.6 150.9 8.3 7.6 25.1 2.8 15.8 7.0 8.1 32.9 7.2 12.3 5.5 18.8 3.9 160.7 2.0 7.9 3.9 498.1 8.3 5.4 5.0 3.6 22.9 0.3 3.7 3.2 8.0 5.6 3.4 40.5 1.8 7.1 5.3 7.5 0.0 1.9 2.7 8.2 26.2 39.5 3430.7 20.2 27.9 24.9 2.8 38.3 11.7 332.7 0.5 1.0 5.5 0.0 15.4 68.0 4.6 1.3 3.8 44.6 20.4 19.7 7.5 8.1 15.6 10.5 1.5 7.4 4.4 268.3 0.9 1.6 3.5 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACER1 ASAH3 ENSG00000167769 "Alkaline ceramidase 1" Q8TDN7 19 6306142-6333612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 88.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.7;Inhibitory neurons: 2.1;Melanocytes: 1.8;Spermatocytes: 1.7;Suprabasal keratinocytes: 5.8" "Group enriched" "Detected in some" 7 "head and neck cancer: 1.0;melanoma: 2.2;prostate cancer: 0.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Cell line enhanced" "Detected in single" "T-47d: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (1.13e-2)" "unprognostic (2.87e-4)" "unprognostic (5.04e-2)" "unprognostic (6.18e-2)" "unprognostic (8.16e-4)" "unprognostic (7.27e-4)" "unprognostic (2.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.99e-1)" "unprognostic (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.30e-5)" "unprognostic (2.11e-1)" "unprognostic (4.44e-2)" "unprognostic (4.22e-1)" "unprognostic (2.24e-1)" 0.1 0.1 0.1 0.1 0.1 0.1 3.3 0.4 0.2 3.4 0.3 0.0 0.0 0.2 0.2 12.2 0.2 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.5 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.2 1.7 0.0 0.0 3.2 0.1 0.5 88.1 0.2 0.1 0.0 0.3 0.0 1.1 0.2 1.3 0.0 0.0 0.7 0.0 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.2 0.5 0.0 0.1 0.7 0.7 0.1 0.3 0.0 0.1 0.8 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.1 0.9 1.0 1.8 0.0 0.0 0.0 0.0 1.0 0.5 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.7 1.0 0.0 5.8 0.0 0.4 0.0 0.0 0.1 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 104.2;Late spermatids: 90.3;Proximal enterocytes: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 8.3 31.7 27.8 8.6 29.8 18.1 7.6 28.2 35.2 9.3 24.3 18.5 21.1 8.5 11.0 17.5 10.7 9.2 28.1 29.8 28.6 21.3 26.0 11.0 12.6 27.0 28.5 8.0 15.6 15.1 15.4 7.1 28.7 12.7 12.8 9.2 12.8 5.9 28.7 17.0 20.5 6.4 26.0 12.3 21.3 20.2 28.7 13.1 11.4 17.8 9.7 11.0 10.4 28.1 16.8 20.2 6.8 13.4 18.3 11.0 11.7 11.1 9.5 15.1 13.7 29.2 22.7 20.8 48.2 16.3 35.4 32.3 13.0 27.8 6.6 15.5 22.3 21.2 25.1 28.5 16.9 19.9 19.3 12.9 21.3 15.1 10.9 22.6 9.4 23.6 18.8 24.2 11.0 47.4 28.7 27.0 11.8 32.4 52.2 14.0 12.2 37.6 16.5 19.1 23.1 10.8 24.9 61.7 39.5 10.6 34.4 48.8 11.6 37.9 8.5 19.5 18.9 20.7 33.8 14.0 46.3 21.2 20.8 34.3 34.3 43.6 24.8 34.6 21.8 27.5 23.2 21.9 36.7 27.9 20.0 21.6 25.0 16.3 34.2 23.3 31.9 26.7 27.8 29.8 28.2 35.2 29.8 28.6 27.0 28.5 28.7 26.0 28.7 28.1 8.2 35.3 14.1 5.9 17.9 6.1 12.3 21.9 8.6 19.2 9.8 10.9 9.3 11.5 17.7 12.9 16.7 34.2 11.8 104.2 64.6 21.6 38.5 14.2 10.4 10.9 19.2 17.0 12.3 21.0 20.9 11.4 19.9 14.0 14.0 27.6 11.4 25.5 27.8 8.4 12.0 37.3 10.2 18.6 7.1 90.3 9.9 17.5 10.6 3.7 27.5 17.8 34.0 5.0 9.6 21.6 68.4 8.6 21.3 11.3 105.4 81.5 27.1 22.8 13.1 5.8 12.8 27.0 10.2 16.1 8.0 19.4 13.9 37.6 30.3 16.0 ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 6.6;lymphoid tissue: 2.6;skin 1: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 0.8;head and neck cancer: 2.6;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 33.3;U-87 MG: 45.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "HPA042613: AB_10963214" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-3)" "unprognostic (1.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (4.94e-3)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" "unprognostic (1.51e-5)" "unprognostic (4.36e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-2)" "unprognostic (2.42e-1)" 0.0 0.0 1.7 0.0 3.3 0.0 0.2 6.6 2.7 0.7 0.8 0.0 0.0 0.0 0.4 0.7 0.0 0.2 0.0 2.0 2.2 0.0 0.0 0.0 0.0 3.9 3.7 0.0 0.0 0.3 0.0 0.0 3.8 0.3 0.0 0.0 0.5 0.0 0.0 6.0 0.0 0.0 2.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 2.6 0.1 0.6 4.1 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.6 0.8 0.4 5.2 0.0 0.0 0.0 33.3 0.3 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.5 0.3 0.0 0.1 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.1 1.1 0.0 0.0 0.0 0.0 0.0 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.3 6.6 2.7 2.0 2.2 3.9 3.7 3.8 2.0 3.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 217.8;intestine: 418.0;liver: 165.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.9;Endometrial ciliated cells: 159.9;Glandular and luminal cells: 292.3;Proximal enterocytes: 462.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 138.8;RT4: 143.3;U-937: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" 23.8 4.2 13.1 29.0 12.6 16.2 21.3 13.0 15.5 51.4 10.4 111.7 358.9 30.3 217.8 7.9 45.0 21.5 9.4 12.1 13.4 9.0 165.5 35.6 28.0 14.4 13.1 17.0 5.5 2.2 2.6 8.6 14.9 12.3 116.6 1.5 5.5 20.3 3.9 3.4 418.0 15.5 14.0 25.7 44.2 9.6 15.3 16.4 7.2 8.8 28.0 76.3 7.6 13.2 38.6 0.9 0.7 0.1 2.5 0.4 3.3 1.1 7.3 0.3 0.6 34.8 138.8 46.7 8.4 1.9 6.8 0.3 0.0 0.2 0.8 39.4 0.0 36.5 1.3 60.9 8.8 57.3 59.2 5.9 0.0 0.8 0.0 2.7 2.8 0.0 0.1 20.6 0.1 0.0 0.1 26.3 0.1 32.2 1.3 12.9 0.2 28.6 3.8 143.3 0.1 0.9 55.8 21.0 0.1 0.1 0.1 31.7 40.5 0.5 0.4 2.2 2.5 14.8 0.1 22.6 1.2 70.5 0.1 27.4 15.1 27.5 25.2 27.9 24.9 16.3 20.4 27.8 31.1 13.1 13.8 21.4 3.9 26.1 27.7 9.8 41.5 21.1 13.1 12.6 13.0 15.5 12.1 13.4 14.4 13.1 14.9 14.0 15.3 13.2 23.4 12.8 51.3 0.0 20.1 3.8 10.3 10.7 8.6 0.1 7.0 4.6 1.7 12.8 23.6 0.0 4.2 1.8 10.5 164.9 0.0 13.3 92.6 159.9 37.6 24.7 40.8 10.7 1.3 6.4 2.6 5.7 41.8 292.3 17.2 0.5 16.1 88.6 18.9 0.0 1.1 79.0 0.0 22.4 57.8 42.6 15.8 24.9 3.6 17.8 11.5 0.1 16.5 1.0 1.0 48.0 122.4 12.0 20.3 7.1 462.5 0.2 8.2 1.2 0.0 0.8 3.3 4.0 1.9 3.3 1.7 0.7 24.0 6.4 103.3 50.0 ACTBL2 DKFZp686D0972 ENSG00000169067 "Actin beta like 2" Q562R1 5 57480018-57482811 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.1;Club cells: 1.0;Ductal cells: 1.7;Early spermatids: 2.4;Exocrine glandular cells: 1.1;Pancreatic endocrine cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 1.3;RPTEC TERT1: 1.6;SiHa: 2.9;U-2 OS: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041264, HPA041271" Uncertain NA NA 830000000 "Cluster 38: EFO-21 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.83e-2)" "unprognostic (1.70e-1)" "unprognostic (2.96e-1)" "unprognostic (8.66e-2)" "unprognostic (2.57e-2)" "unprognostic (2.39e-1)" "unprognostic (3.63e-2)" "unprognostic (1.22e-1)" "unprognostic (1.14e-3)" "unprognostic (3.20e-1)" "unprognostic (2.48e-3)" "unprognostic (1.60e-2)" "unprognostic (2.04e-2)" "unprognostic (1.92e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 1.1 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;ovary: 10.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 7.3;Excitatory neurons: 44.7;Fibroblasts: 13.7;Granulosa cells: 22.2;Theca cells: 15.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;SuSa: 3.5;U-2197: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067668 Approved "Nucleoplasm,Nuclear membrane,Midbody ring,Mitochondria" "Secreted to extracellular matrix" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" "Nucleoplasm, Midbody ring" "HPA067668: " "unprognostic (8.48e-2)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (5.04e-2)" "unprognostic (7.64e-2)" "unprognostic (7.80e-3)" "unprognostic (2.12e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-2)" "unprognostic (2.18e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (4.59e-3)" "unprognostic (2.86e-3)" 5.4 0.2 1.4 0.4 1.9 0.5 0.7 17.0 2.6 1.4 0.0 0.7 0.6 1.3 1.6 1.5 0.7 6.4 0.2 3.4 0.0 3.5 0.4 0.7 0.2 0.2 0.2 10.4 4.5 0.1 0.0 0.2 0.7 0.1 0.3 1.2 0.2 0.5 0.2 0.4 0.5 1.1 0.0 0.2 0.2 0.4 0.0 0.2 0.3 0.2 0.1 1.0 0.6 1.8 1.7 1.7 1.7 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.5 0.0 1.4 0.1 2.1 0.0 3.0 0.1 0.0 0.0 0.4 0.1 0.9 0.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 3.9 0.1 0.5 0.0 0.3 0.6 0.4 0.7 0.0 0.4 0.2 1.1 0.0 1.6 0.4 2.2 0.1 0.0 0.1 0.5 0.1 0.1 0.1 0.1 3.5 0.1 0.1 0.1 2.1 3.0 5.8 1.4 0.9 0.3 0.1 3.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 1.9 17.0 2.6 3.4 0.0 0.2 0.2 0.7 0.0 0.0 1.8 0.7 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.6 2.0 0.7 0.4 0.5 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 5.0 0.1 0.0 0.0 44.7 0.0 0.0 13.7 0.5 0.5 0.0 22.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 1.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 6.9 1.6 0.1 0.0 0.0 0.0 0.0 0.1 15.9 0.0 0.0 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 71.9;placenta: 47.4" "Cell type enhanced" "Detected in many" "Endothelial cells: 41.7;Hepatocytes: 143.8;Kupffer cells: 40.5;Pancreatic endocrine cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 88.6;Hep G2: 84.8;hTERT-HME1: 81.5;HUVEC TERT2: 161.4;MCF7: 155.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017346 Approved NA NA 110000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017346: AB_1849260" "unprognostic (1.04e-2)" "unprognostic (2.72e-2)" "unprognostic (7.37e-2)" "unprognostic (3.00e-2)" "unprognostic (8.64e-4)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.46e-1)" "unprognostic (6.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.97e-2)" "unprognostic (4.59e-2)" 5.8 2.8 2.6 4.1 2.3 0.4 5.2 1.6 1.9 3.0 1.9 6.2 17.5 1.1 1.3 11.6 5.2 8.3 4.0 1.8 1.7 7.2 71.9 15.2 1.7 2.4 2.9 1.4 3.2 1.3 0.3 47.4 2.2 3.2 6.4 0.1 9.0 6.5 0.5 14.5 10.2 2.2 2.5 7.5 12.3 2.1 4.6 4.6 1.6 1.2 4.0 15.1 5.6 1.9 17.0 88.6 1.9 9.4 0.5 0.0 0.2 23.1 4.3 17.2 10.7 71.3 51.0 0.0 20.3 13.4 4.9 41.3 2.6 22.1 28.3 0.0 6.8 3.6 14.5 84.8 16.7 14.6 0.0 0.1 34.9 0.4 81.5 10.0 161.4 0.4 0.6 0.1 6.9 155.6 0.3 0.0 0.7 6.2 20.0 0.0 7.7 17.7 9.0 37.9 0.1 0.1 6.8 30.8 14.5 14.1 16.7 0.3 5.6 0.1 7.6 7.7 11.5 0.0 0.1 0.0 0.1 0.1 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.3 1.6 1.9 1.8 1.7 2.4 2.9 2.2 2.5 4.6 1.9 5.1 6.4 5.9 0.0 0.3 0.0 21.9 0.0 18.8 0.0 5.3 2.7 1.9 24.3 8.1 9.2 0.0 5.3 0.0 0.6 0.0 13.2 0.1 0.1 0.5 41.7 0.0 17.0 1.6 5.4 33.5 14.5 32.1 0.5 0.0 0.0 27.1 143.8 2.2 0.0 12.7 3.5 0.0 40.5 0.0 0.6 0.6 8.1 0.0 15.0 0.9 0.0 0.0 0.5 0.3 37.9 8.8 0.4 0.1 18.7 9.5 11.8 2.9 0.0 6.6 0.4 1.3 2.6 5.3 30.2 0.0 13.5 1.6 0.0 1.7 25.0 ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61201258-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3" "Group enriched" "Detected in many" 11 "Astrocytes: 584.1;Excitatory neurons: 696.1;Inhibitory neurons: 737.4;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 592.1" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 41.8;EFO-21: 10.8;HEK 293: 6.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" 7.1 6.2 25.1 1.1 25.7 0.0 2.5 14.0 30.7 5.5 0.0 4.0 2.5 3.9 1.8 1.0 2.4 1.6 2.6 30.4 25.0 1.6 0.4 2.6 0.4 15.3 24.6 1.1 0.3 6.7 0.9 1.2 15.9 1.3 3.9 10.0 0.6 4.2 0.7 3.0 3.6 3.0 12.5 0.3 3.2 4.1 32.3 0.4 0.7 0.3 0.1 1.6 3.4 15.7 0.0 0.1 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 3.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 1.0 0.0 4.0 0.5 0.1 0.1 0.0 4.8 0.2 0.0 6.3 0.3 0.0 0.0 0.0 7.6 0.1 3.2 0.0 0.2 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 25.7 14.0 30.7 30.4 25.0 15.3 24.6 15.9 12.5 32.3 15.7 0.4 0.0 0.0 584.1 0.0 0.0 0.0 0.0 0.6 12.4 4.9 1.8 3.3 0.0 0.0 0.0 4.2 1.0 0.0 0.0 9.8 0.0 46.4 1.3 17.7 1.9 0.0 0.0 696.1 0.0 1.3 3.3 0.0 0.4 0.0 0.4 2.5 0.2 0.1 1.7 737.4 0.0 0.0 0.0 0.0 33.2 0.0 0.5 0.0 70.3 0.0 31.3 0.0 1300.8 592.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.4 6.6 0.3 18.5 0.9 3.5 1.2 0.0 2.2 0.2 0.1 0.0 0.1 ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "adrenal gland: 533.0" "Cell type enriched" "Detected in many" 8 "Astrocytes: 2207.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 15.5;HAP1: 23.0;K-562: 9.8;NTERA-2: 11.6;SCLC-21H: 11.1;SuSa: 15.0;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" 0.0 533.0 36.9 0.0 47.8 0.6 3.6 12.7 40.3 0.9 22.4 1.0 0.3 0.1 0.7 2.4 0.2 12.3 0.2 39.1 11.6 21.5 42.3 2.1 0.0 9.4 12.8 0.2 1.5 0.8 15.1 4.1 9.4 1.3 1.0 18.2 2.3 0.2 0.2 2.1 0.5 0.0 7.3 0.3 1.1 1.4 18.3 0.8 17.5 0.0 0.4 10.4 1.9 26.1 0.5 2.1 15.5 0.0 0.0 0.1 0.2 0.3 0.1 0.0 0.0 1.7 0.2 0.3 0.4 0.0 0.4 0.2 23.0 0.2 0.0 1.0 4.3 4.1 2.0 1.4 0.0 0.3 0.1 0.0 4.8 0.0 0.1 0.1 0.0 0.1 9.8 2.6 0.0 2.1 0.1 0.2 11.6 2.9 4.2 0.0 0.4 2.1 0.0 0.5 11.1 2.7 3.4 2.2 0.2 15.0 5.9 0.0 0.8 0.4 1.9 0.5 1.1 13.4 4.1 0.6 0.7 0.2 0.0 3.2 0.9 2.8 1.0 0.7 1.7 1.5 1.1 1.4 0.5 2.9 1.7 0.9 4.6 1.1 0.5 1.2 1.6 0.2 36.9 47.8 12.7 40.3 39.1 11.6 9.4 12.8 9.4 7.3 18.3 26.1 0.4 25.6 26.5 2207.3 0.0 0.0 6.1 0.0 1.8 28.0 15.5 7.4 2.4 2.8 5.6 5.5 264.8 3.0 0.4 0.6 1.9 1.9 43.5 3.3 0.3 1.1 7.3 0.0 54.0 4.2 2.6 1.1 4.6 1.9 0.0 6.7 0.0 12.4 0.2 10.1 21.9 0.4 0.0 0.8 0.0 54.8 0.6 0.5 0.0 51.5 1.2 8.9 1.0 40.2 7.4 1.7 1.2 0.4 0.1 2.1 0.1 24.2 7.3 84.4 0.0 0.3 0.4 3.6 4.5 2.9 0.0 4.1 0.6 0.2 1.2 9.0 ADIPOR1 "ACDCR1, PAQR1" ENSG00000159346 "Adiponectin receptor 1" Q96A54 1 202940826-202958572 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 329.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (3.81e-2)" "unprognostic (2.74e-1)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (9.95e-2)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.27e-4)" "prognostic unfavorable (5.50e-4)" "unprognostic (1.13e-1)" "unprognostic (1.79e-3)" "unprognostic (5.90e-2)" "unprognostic (1.75e-1)" "unprognostic (2.84e-1)" "unprognostic (8.63e-2)" 59.8 58.5 56.1 49.1 60.1 215.2 63.6 58.7 64.2 55.4 82.9 55.6 46.5 40.9 91.4 110.9 68.6 48.2 92.6 56.8 57.7 70.4 106.2 80.5 48.0 61.2 58.6 47.7 91.7 107.1 45.5 100.0 60.2 53.7 59.8 135.6 106.6 47.4 136.5 110.8 47.4 50.9 60.1 65.8 63.3 48.7 58.7 50.2 56.6 140.2 77.9 70.9 69.2 65.2 97.0 87.2 53.4 59.9 111.4 85.4 276.8 103.4 123.9 108.8 99.4 88.7 114.7 63.5 75.3 120.6 86.3 118.0 81.3 145.5 96.5 118.5 93.5 48.6 104.3 72.6 109.7 101.6 71.6 101.7 235.0 115.9 118.3 108.4 108.8 111.7 128.1 133.5 111.2 105.6 85.3 77.4 119.7 87.1 103.1 66.7 128.7 125.7 106.5 111.0 89.2 90.8 109.6 166.5 135.5 143.6 121.1 99.4 95.7 78.9 62.2 39.4 117.3 137.8 197.4 71.4 113.5 58.9 94.5 362.2 361.8 455.4 136.0 253.6 143.8 157.9 143.4 134.1 209.8 165.2 141.5 124.3 825.9 126.0 259.6 146.1 179.5 557.4 56.1 60.1 58.7 64.2 56.8 57.7 61.2 58.6 60.2 60.1 58.7 65.2 40.7 35.3 52.5 6.8 46.8 235.0 95.2 109.8 75.7 24.8 81.9 54.2 59.7 32.9 79.3 53.3 29.2 112.7 42.8 49.3 68.4 73.8 68.2 58.8 24.5 53.4 49.1 329.0 13.7 86.3 172.4 40.9 37.2 54.3 37.3 18.8 58.5 60.8 104.2 11.8 15.1 49.1 85.5 148.5 89.7 62.5 28.6 107.6 85.4 15.9 85.0 38.0 42.2 9.5 20.0 120.0 43.5 24.5 116.0 133.1 67.3 65.9 82.5 54.9 39.5 29.2 61.7 26.4 27.2 79.3 228.9 202.8 47.1 29.2 41.7 206.6 ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;liver: 60.1" "Cell type enhanced" "Detected in some" "Astrocytes: 105.4;Early spermatids: 51.3;Inhibitory neurons: 123.2;Late spermatids: 28.3;Oligodendrocyte precursor cells: 114.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" 21.8 0.5 13.3 1.1 11.1 0.0 3.6 3.0 22.6 0.7 0.0 1.4 0.9 1.4 0.6 0.8 0.2 0.3 7.6 42.6 20.8 0.7 60.1 3.9 1.7 9.3 4.9 0.9 0.0 0.0 0.1 0.0 9.5 12.4 0.5 0.3 6.2 13.5 0.2 0.6 1.1 2.9 1.5 9.2 0.9 0.1 4.2 0.1 0.1 1.4 0.4 0.4 0.3 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 11.1 3.0 22.6 42.6 20.8 9.3 4.9 9.5 1.5 4.2 6.9 0.0 0.0 0.0 105.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 16.2 0.0 0.0 123.2 0.0 0.0 0.0 0.5 28.3 0.6 0.0 0.0 9.4 0.0 0.0 0.0 114.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 ADTRP "AIG1L, C6orf105, dJ413H6.1" ENSG00000111863 "Androgen dependent TFPI regulating protein" Q96IZ2 6 11712054-11807046 "Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 98.5;parathyroid gland: 92.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 116.4;Distal tubular cells: 52.8;Early spermatids: 141.6;Late spermatids: 168.0;Paneth cells: 87.0;Proximal enterocytes: 127.0;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 14.8;T-reg: 13.5" "Lineage enriched" "Detected in many" 5 "T-cells: 14.8" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 93.9;RPMI-8226: 41.2;TIME: 57.7;U-138 MG: 42.4;U-266/84: 47.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA048113 Uncertain Uncertain Nucleoli NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoli "HPA048113: AB_2680268" "unprognostic (6.82e-3)" "unprognostic (1.41e-1)" "unprognostic (1.58e-1)" "unprognostic (8.14e-3)" "unprognostic (3.04e-3)" "unprognostic (1.41e-2)" "unprognostic (4.00e-2)" "unprognostic (1.77e-1)" "unprognostic (1.85e-2)" "unprognostic (2.72e-1)" "unprognostic (5.41e-3)" "unprognostic (2.90e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (2.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.95e-2)" "unprognostic (1.26e-1)" 0.5 0.2 1.9 14.2 2.1 1.1 3.3 0.6 2.2 0.4 35.2 80.7 82.4 0.3 13.7 1.5 0.6 1.6 0.3 2.0 0.0 9.8 1.4 11.1 9.4 0.1 0.1 0.2 0.8 92.9 0.0 2.4 0.1 0.4 58.5 0.6 0.8 24.4 1.0 18.9 98.5 2.6 0.1 1.3 38.2 22.6 0.4 2.6 0.5 0.1 12.7 10.2 0.3 1.1 4.1 0.0 0.0 0.0 0.5 0.9 0.1 1.5 0.8 1.0 0.7 3.6 1.9 0.1 1.7 0.7 2.4 1.9 0.0 11.2 1.4 0.1 0.0 0.3 0.8 0.1 0.3 0.1 0.2 0.0 20.4 10.4 23.6 17.5 93.9 0.7 23.0 0.0 3.1 0.1 0.2 0.6 0.3 0.1 5.8 0.0 0.3 41.2 1.7 0.2 0.1 0.2 1.5 0.0 0.8 2.8 0.0 0.8 57.7 42.4 2.0 0.7 2.6 1.2 47.1 0.0 7.9 1.3 0.2 2.7 0.0 0.0 0.0 0.3 2.6 0.2 3.7 0.3 0.1 0.2 14.8 1.3 0.3 0.1 0.2 0.2 13.5 1.7 1.9 2.1 0.6 2.2 2.0 0.0 0.1 0.1 0.1 0.1 0.4 1.1 0.2 0.0 1.1 0.7 4.0 5.1 0.3 3.9 0.6 0.0 0.1 1.9 0.1 0.0 2.6 5.5 0.0 0.2 0.1 116.4 52.8 0.7 141.6 0.2 0.0 0.3 5.4 2.7 13.1 2.4 0.2 1.1 32.1 0.1 5.7 0.0 0.0 0.2 11.4 0.0 0.4 40.7 2.0 0.8 1.5 168.0 1.8 3.1 1.8 0.0 27.9 0.0 1.0 1.0 0.1 7.9 87.0 0.7 7.8 0.6 127.0 0.7 0.8 0.0 0.0 0.2 1.2 1.6 0.7 0.4 5.7 0.1 6.2 0.0 52.3 0.5 AEBP2 MGC17922 ENSG00000139154 "AE binding protein 2" Q6ZN18 12 19404045-19720801 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020893, HPA022282" Uncertain Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA020893: AB_2670528, HPA022282: AB_2670931" "unprognostic (3.28e-1)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (3.16e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (9.15e-2)" "unprognostic (4.56e-2)" "unprognostic (5.19e-3)" "unprognostic (1.87e-1)" "unprognostic (3.45e-2)" "unprognostic (1.68e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-1)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" 19.0 27.2 9.9 20.0 11.6 20.5 23.5 13.0 16.5 25.8 12.5 18.8 16.3 34.0 20.2 35.1 28.0 21.8 17.8 17.7 7.2 27.8 20.3 20.7 27.7 1.9 6.7 35.1 17.5 29.9 8.9 44.1 2.0 24.8 20.6 27.7 19.3 30.7 13.6 29.4 16.7 31.1 0.3 23.1 16.1 20.8 11.8 29.2 30.8 19.8 32.3 25.0 18.2 14.7 32.4 42.4 42.6 20.1 31.1 38.6 95.2 29.9 34.1 43.5 45.7 48.0 54.5 51.0 24.3 41.4 27.6 38.0 93.7 34.6 69.1 149.4 30.6 46.7 60.8 30.0 36.4 60.1 30.8 36.2 36.3 35.6 52.8 52.0 35.6 34.8 25.2 1.4 41.2 38.5 63.0 71.7 82.6 26.6 18.9 50.3 82.3 35.9 32.2 68.2 10.0 23.4 60.6 25.7 29.8 91.3 32.8 35.0 40.5 40.7 30.9 12.8 44.9 14.0 24.9 106.0 30.3 25.1 29.2 4.3 2.5 2.5 4.2 2.7 4.4 2.2 4.4 3.6 2.0 2.8 3.7 5.8 2.7 6.0 2.2 2.6 4.5 1.2 9.9 11.6 13.0 16.5 17.7 7.2 1.9 6.7 2.0 0.3 11.8 14.7 23.9 25.6 14.3 31.6 20.5 75.2 25.1 15.5 53.5 29.8 22.0 13.3 22.1 12.8 24.2 12.9 43.8 60.3 24.3 9.5 17.6 12.3 1.3 31.1 31.5 22.2 22.7 11.6 57.2 12.2 24.8 28.3 14.3 28.8 27.8 17.7 14.3 12.9 15.4 52.2 59.4 11.2 4.1 17.0 47.9 2.3 24.5 17.8 28.4 30.0 17.7 21.5 14.4 42.3 51.6 11.5 10.3 29.0 18.3 24.5 9.0 18.3 26.1 16.1 19.7 46.7 40.1 16.2 26.3 51.0 76.0 83.0 28.1 34.2 10.7 28.2 AFAP1 "AFAP, AFAP-110" ENSG00000196526 "Actin filament associated protein 1" Q8N556 4 7758714-7939926 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 170.5;Extravillous trophoblasts: 116.3;Inhibitory neurons: 117.2;Late spermatids: 373.8;Oligodendrocyte precursor cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.9;T-cells: 1.2" "Cell line enhanced" "Detected in many" "TIME: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015642, CAB024712" Enhanced Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" "Focal adhesion sites" "CAB024712: , HPA015642: AB_1844632" "unprognostic (1.12e-1)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.00e-1)" "unprognostic (3.39e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.44e-2)" 12.6 3.1 7.0 8.7 5.8 0.7 9.7 4.5 6.9 8.7 2.9 17.6 5.6 15.4 2.0 11.0 8.5 9.4 10.8 5.8 4.5 4.9 1.2 8.5 4.4 3.7 2.7 7.1 3.8 14.7 7.9 12.6 2.8 7.7 9.8 3.4 8.6 10.2 3.5 5.3 7.7 15.4 3.4 4.0 6.7 22.0 3.5 3.1 7.4 2.4 4.8 14.2 8.3 3.5 31.9 23.2 16.2 12.9 15.4 27.8 21.3 46.4 68.1 43.6 40.0 7.4 7.2 0.1 15.2 75.5 72.3 15.1 8.6 18.7 28.6 0.9 5.7 0.0 33.2 4.5 43.0 0.0 0.4 17.2 13.8 54.4 35.5 72.2 53.0 4.8 0.7 6.8 23.0 10.3 0.6 0.0 7.0 13.2 44.3 0.0 12.1 1.5 4.7 4.1 31.8 53.0 15.9 10.9 12.4 21.4 4.1 0.3 126.7 53.0 11.8 69.6 23.0 0.0 0.2 0.0 18.9 0.1 61.9 0.0 0.4 2.9 0.4 0.1 0.5 0.0 0.6 0.6 0.0 0.0 1.2 0.5 1.0 0.0 0.0 0.0 0.5 0.7 7.0 5.8 4.5 6.9 5.8 4.5 3.7 2.7 2.8 3.4 3.5 3.5 22.5 6.4 2.0 4.6 0.2 2.9 9.7 16.2 7.4 1.2 10.2 8.9 5.9 10.0 12.7 11.0 4.2 5.6 2.3 14.8 0.0 19.2 170.5 7.5 17.6 20.1 14.5 0.0 24.7 7.7 116.3 21.1 11.2 8.8 0.0 4.4 14.3 0.0 8.5 0.0 117.2 20.6 0.0 0.3 3.6 373.8 11.1 6.0 1.8 30.9 0.6 10.2 0.0 125.2 5.4 29.9 8.6 12.4 0.6 13.5 6.4 4.2 6.4 0.7 6.6 8.0 13.4 12.5 10.0 6.2 4.3 8.8 7.3 2.6 13.9 9.9 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 122.5" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.0;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 38.5;Proximal enterocytes: 30.5;Proximal tubular cells: 16.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HSkMC: 3.5;Karpas-707: 7.7;NTERA-2: 3.5;SCLC-21H: 3.2;TIME: 4.0;WM-115: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 2.8 0.1 0.9 0.6 2.4 0.1 1.8 0.7 1.9 0.1 0.1 1.2 9.7 0.1 14.5 0.1 0.1 3.6 0.4 0.7 1.4 8.9 122.5 0.2 0.5 1.5 1.4 0.1 0.1 0.0 0.4 0.8 1.5 0.0 0.6 0.1 0.2 0.1 0.3 0.2 14.9 0.1 0.9 0.0 0.3 3.0 1.8 0.2 0.4 0.4 0.1 1.2 0.1 4.1 0.0 2.2 0.0 1.9 0.2 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 1.2 0.0 0.7 3.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.0 1.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 15.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 2.4 0.7 1.9 0.7 1.4 1.5 1.4 1.5 0.9 1.8 4.1 10.0 0.0 0.0 6.8 0.3 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.1 11.5 0.4 3.7 0.0 0.1 0.1 0.5 0.0 0.0 1.3 0.3 0.1 1.2 1.8 2.7 1.3 0.0 0.2 1.2 0.0 0.0 0.0 0.0 1.1 83.0 0.1 0.0 1.7 0.4 0.0 1.6 0.5 1.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 33.7 38.5 0.9 0.1 0.0 0.0 0.0 30.5 16.9 0.3 0.0 6.6 0.4 2.4 1.7 6.4 0.1 0.0 0.1 0.2 0.1 0.6 0.0 AGO4 "EIF2C4, FLJ20033, hAGO4, KIAA1567" ENSG00000134698 "Argonaute RISC component 4" Q9HCK5 1 35808016-35857890 "Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 60.6;Inhibitory neurons: 72.0;Microglial cells: 63.7;Oligodendrocyte precursor cells: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "THP-1: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012179, HPA067849" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Cytoplasmic bodies" Cytosol "CAB012179: , HPA067849: " "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (5.01e-2)" "unprognostic (1.76e-1)" "prognostic favorable (5.70e-5)" "unprognostic (3.92e-3)" "unprognostic (3.99e-3)" "unprognostic (2.32e-2)" "unprognostic (9.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-3)" "unprognostic (4.91e-3)" "unprognostic (4.96e-2)" "unprognostic (2.58e-1)" "unprognostic (3.96e-1)" "unprognostic (1.58e-2)" 8.8 4.9 7.2 8.8 7.1 20.4 7.7 8.6 7.9 8.4 8.6 9.6 4.7 8.9 6.6 7.3 7.2 6.2 9.9 6.8 6.8 5.0 7.5 11.4 7.0 7.4 7.1 7.0 8.6 6.5 5.8 8.9 7.4 8.1 6.4 18.1 8.4 6.1 13.3 20.1 7.8 9.8 6.8 14.2 9.7 7.3 7.3 7.3 5.5 11.8 6.8 8.2 8.5 7.6 6.0 1.5 11.3 6.5 5.8 6.6 5.7 4.5 4.4 4.6 5.3 0.8 9.0 9.6 6.0 6.6 4.7 2.4 4.9 3.6 4.3 10.7 4.5 4.9 4.2 2.8 5.5 5.6 7.2 4.3 7.6 2.5 3.8 8.8 7.9 11.5 3.7 3.7 6.2 0.9 9.1 6.2 3.7 3.8 2.7 9.0 10.1 1.2 4.5 7.4 5.0 7.3 4.1 3.7 12.7 9.6 3.0 24.6 9.5 3.5 1.7 3.6 3.4 5.4 1.8 1.4 4.3 7.0 3.2 1.3 2.7 3.0 0.8 1.5 1.4 0.6 0.7 1.1 2.0 0.4 0.3 0.4 7.5 0.6 1.4 0.4 0.2 0.8 7.2 7.1 8.6 7.9 6.8 6.8 7.4 7.1 7.4 6.8 7.3 7.6 16.4 19.2 21.7 54.9 6.7 9.8 4.7 5.4 9.6 28.2 8.5 7.1 21.8 12.8 9.2 11.0 22.9 4.2 17.9 5.5 1.9 5.6 2.0 12.7 9.4 11.6 12.6 5.0 60.6 5.6 4.7 7.2 10.7 10.9 2.5 11.4 22.1 11.5 13.5 6.7 72.0 8.4 2.0 42.3 10.0 1.6 5.0 28.9 3.6 63.7 33.6 6.5 6.2 87.4 54.8 14.4 11.7 5.7 4.3 9.0 10.0 1.5 10.3 32.2 19.7 6.8 8.5 11.3 1.6 5.9 12.8 4.1 10.3 3.6 5.7 6.7 AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 305.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 114.3;Basal respiratory cells: 83.8;Horizontal cells: 60.6;Ionocytes: 61.1;Pancreatic endocrine cells: 68.2;Respiratory ciliated cells: 66.8;Squamous epithelial cells: 63.7;Suprabasal keratinocytes: 164.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 135.1;HBEC3-KT: 124.9;hTCEpi: 308.7;hTERT-HME1: 130.3;TIME: 138.4" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 11.3;midbrain: 10.6;pons: 13.2;spinal cord: 38.9;thalamus: 15.0" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 40000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA000878: AB_2666127, HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: AB_2670371" "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.23e-5)" 30.4 2.3 9.8 2.4 9.9 0.0 16.4 9.3 15.9 84.5 4.6 105.3 1.4 64.3 2.9 114.1 29.2 5.1 4.5 9.7 16.0 3.5 6.2 5.1 0.1 38.1 15.3 3.5 1.6 0.7 3.4 1.8 40.8 18.6 8.6 19.0 24.0 28.6 3.6 305.9 20.2 31.6 12.4 0.9 25.2 7.7 18.1 0.4 2.8 4.5 4.7 49.4 86.6 18.5 2.9 107.6 0.1 6.0 120.0 135.1 0.2 10.5 22.3 3.8 1.9 0.3 38.9 0.1 14.5 82.9 85.3 62.9 0.3 124.9 1.7 0.0 0.4 0.0 67.5 0.5 11.0 0.0 3.8 17.6 308.7 12.1 130.3 52.3 54.7 0.0 0.0 0.2 62.8 8.0 0.0 0.0 0.3 9.5 42.9 0.3 5.7 0.1 84.4 0.0 0.6 0.6 46.2 0.1 2.3 2.8 6.0 0.0 138.4 29.3 17.9 33.8 9.9 0.0 0.0 0.0 88.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.8 9.9 9.3 15.9 9.7 16.0 38.1 15.3 40.8 12.4 18.1 18.5 3.8 12.8 1.1 0.3 0.0 114.3 4.9 83.8 13.1 8.9 2.2 1.3 1.5 0.0 38.2 1.8 2.1 0.2 0.3 0.4 0.0 11.9 24.2 16.0 10.5 13.0 0.0 0.0 8.2 8.7 0.5 31.9 0.0 18.9 17.1 0.1 3.6 2.1 1.0 60.6 5.1 0.0 61.1 0.3 12.7 3.1 0.6 0.7 32.0 3.7 0.0 3.2 0.0 1.5 3.3 68.2 0.0 0.4 0.0 4.5 0.0 0.3 66.8 13.9 0.0 13.1 8.6 0.4 4.3 63.7 164.7 0.1 0.9 0.1 0.2 6.2 AJUBA "JUB, MGC15563" ENSG00000129474 "Ajuba LIM protein" Q96IF1 14 22971177-22982551 "Cancer-related genes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 61.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 47.5;Basal squamous epithelial cells: 35.3;Pancreatic endocrine cells: 33.8;Prostatic glandular cells: 34.2;Sertoli cells: 32.9;Suprabasal keratinocytes: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 217.0;hTCEpi: 222.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006171 Approved Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Golgi apparatus" "HPA006171: AB_1852044" "unprognostic (1.15e-1)" "unprognostic (2.99e-2)" "unprognostic (2.39e-1)" "unprognostic (1.24e-3)" "unprognostic (9.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-3)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.47e-1)" "unprognostic (3.19e-3)" "unprognostic (2.94e-1)" "unprognostic (2.68e-1)" "unprognostic (9.35e-3)" "unprognostic (2.07e-1)" 4.8 3.0 2.3 1.4 1.8 0.5 6.7 2.0 2.2 14.4 9.2 3.2 1.5 12.1 8.5 18.3 7.5 4.9 6.3 2.2 1.5 17.7 43.4 15.2 2.6 2.5 2.1 12.2 11.6 7.2 2.0 19.3 1.6 10.6 2.5 3.7 8.2 15.9 1.9 61.7 1.9 8.4 2.2 3.8 4.2 5.5 1.9 8.2 10.9 2.3 5.5 7.6 15.5 2.7 46.9 54.1 71.0 27.6 6.8 12.2 57.4 44.9 58.5 102.6 91.4 116.0 47.3 1.2 45.5 92.9 70.8 146.2 54.9 217.0 124.6 4.5 5.0 3.5 90.8 131.4 78.9 4.9 3.1 38.9 222.3 42.9 164.3 72.7 40.0 8.3 1.9 2.8 96.2 37.3 4.5 5.7 4.5 86.6 73.9 12.7 59.0 1.2 103.9 71.3 0.2 6.2 135.5 39.4 8.8 57.4 55.3 4.5 36.1 44.2 88.4 7.3 43.6 0.4 1.3 0.5 7.0 4.2 20.6 0.7 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.5 0.1 0.2 0.3 0.2 0.5 0.5 0.2 0.2 0.0 0.1 2.3 1.8 2.0 2.2 2.2 1.5 2.5 2.1 1.6 2.2 1.9 2.7 2.1 19.2 6.4 0.7 0.0 47.5 13.0 27.6 35.3 0.1 3.7 9.7 4.5 20.0 10.2 7.3 0.0 10.0 0.1 0.3 5.9 14.3 5.8 13.0 2.5 4.0 0.0 0.0 0.0 14.9 9.8 3.4 0.0 4.4 0.0 12.8 2.5 17.1 1.7 0.0 0.0 0.4 2.0 0.0 2.2 5.0 3.7 0.6 3.6 0.0 0.0 8.1 0.0 0.5 0.0 33.8 0.1 0.7 1.2 34.2 0.3 21.0 8.3 0.2 32.9 2.7 14.0 7.0 2.7 14.2 49.6 4.0 0.5 1.6 0.8 18.0 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 389.5;Basal squamous epithelial cells: 274.3;Club cells: 150.1;Gastric mucus-secreting cells: 437.9;Respiratory ciliated cells: 412.7;Squamous epithelial cells: 342.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "A549: 5094.7;OE19: 6071.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 1.7 1.0 0.4 1.3 0.7 0.1 3.2 0.3 0.4 6.7 17.5 4.5 6.2 0.3 0.2 496.1 5.5 10.3 0.3 1.0 0.4 1.3 1.9 10.9 0.5 0.6 2.1 0.4 0.5 0.0 0.9 0.0 0.5 1.9 3.3 0.1 128.0 1.5 1.3 72.6 3.5 0.4 0.9 0.9 224.8 1.6 1.3 0.6 0.5 0.3 33.7 6.2 22.3 0.9 0.1 5094.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 10.7 246.5 0.0 2.7 0.5 2.0 29.3 0.7 12.8 0.0 0.0 0.8 0.1 116.6 1.0 0.3 0.1 0.5 0.0 14.9 0.5 0.4 0.2 0.5 0.0 0.0 0.0 0.0 9.7 0.1 0.3 0.4 6071.6 19.8 0.0 0.0 0.0 0.0 87.0 0.2 0.6 24.8 0.0 0.0 0.2 0.2 0.9 0.6 0.3 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.4 1.0 0.4 0.6 2.1 0.5 0.9 1.3 0.9 0.7 3.2 5.5 0.0 0.7 44.1 46.8 389.5 274.3 0.0 0.1 1.5 0.4 2.8 150.1 0.0 0.0 0.0 0.0 5.1 0.0 1.4 1.5 12.4 0.2 1.3 1.8 0.0 0.1 0.5 0.0 1.6 437.9 0.8 2.5 0.3 1.4 3.2 0.2 0.0 0.0 4.8 83.4 0.3 1.8 5.2 0.9 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 9.5 4.7 1.9 3.2 5.8 3.4 5.0 412.7 0.2 0.0 1.7 20.1 1.7 8.6 342.2 32.0 0.0 0.5 0.2 8.4 64.3 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 162.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 414.1;Proximal tubular cells: 302.1;Syncytiotrophoblasts: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 256.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 430000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 23.7 38.3 46.6 9.1 47.6 1.8 47.1 43.7 45.8 32.7 40.7 29.5 23.7 25.1 8.8 35.9 28.8 19.1 27.9 44.7 43.2 115.1 162.2 15.7 8.6 43.1 43.5 65.3 27.0 34.0 8.8 44.9 42.6 42.0 27.4 19.7 40.6 27.9 12.2 29.4 21.0 23.6 44.8 7.0 23.6 12.3 44.0 18.3 47.6 26.5 17.1 18.1 20.9 45.2 64.9 41.9 116.6 193.4 95.5 56.4 147.8 76.1 93.4 86.5 110.5 118.6 60.7 0.0 75.5 60.0 36.1 47.1 36.5 256.2 78.8 0.1 44.6 12.3 63.1 102.1 46.3 0.2 0.0 69.0 59.2 67.3 47.7 64.2 70.0 0.0 0.0 0.1 77.1 42.1 2.6 0.3 79.4 47.5 35.2 38.9 131.8 0.0 81.2 48.4 39.4 47.2 0.0 41.1 44.7 89.0 75.2 2.7 86.1 24.8 75.6 28.8 53.1 0.1 0.1 0.4 13.4 0.2 40.6 0.7 0.2 0.1 0.1 0.0 0.2 0.8 0.2 0.1 1.8 0.6 1.2 0.6 0.1 0.1 0.0 6.4 0.0 0.4 46.6 47.6 43.7 45.8 44.7 43.2 43.1 43.5 42.6 44.8 44.0 45.2 17.6 16.0 29.3 99.3 5.0 25.9 59.5 110.0 87.0 23.6 40.6 91.1 39.9 27.1 43.5 42.3 22.9 414.1 3.7 15.2 76.3 43.5 31.4 18.7 44.3 19.1 21.7 5.2 16.0 13.8 107.8 34.0 27.0 21.4 7.0 50.4 18.9 74.6 51.1 25.2 21.5 25.9 20.3 9.4 7.6 41.7 25.4 9.1 55.2 12.2 7.5 102.1 0.0 41.7 30.0 12.6 15.6 37.2 2.0 27.5 23.4 302.1 23.4 13.6 19.7 19.4 25.8 1.0 5.1 59.2 16.1 222.3 4.6 39.3 46.4 50.4 ALOX12B 12R-LOX ENSG00000179477 "Arachidonate 12-lipoxygenase, 12R type" O75342 17 8072636-8087716 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 90.2" "Cell type enhanced" "Detected in some" "Horizontal cells: 1.7;Rod photoreceptor cells: 1.2;Spermatogonia: 1.2;Suprabasal keratinocytes: 1.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 4.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.3" "Cell line enhanced" "Detected in some" "A549: 1.1;HEK 293: 1.3;hTCEpi: 1.6;JURKAT: 2.7;OE19: 1.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024002 Supported Supported Vesicles,Cytosol NA NA 7000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Cytosol Vesicles "HPA024002: AB_1844757" "unprognostic (1.27e-2)" "unprognostic (1.59e-2)" "unprognostic (4.28e-3)" "unprognostic (1.38e-2)" "unprognostic (3.94e-3)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.04e-1)" "unprognostic (4.40e-2)" "unprognostic (9.55e-2)" "unprognostic (6.66e-3)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (8.01e-2)" "unprognostic (3.46e-2)" 0.0 0.0 0.4 0.1 0.5 0.1 2.1 0.4 0.6 5.7 0.0 0.1 0.3 0.0 0.0 5.6 0.2 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.5 0.4 0.2 0.0 0.2 1.2 0.1 0.0 0.5 0.4 0.1 0.6 0.8 0.0 0.4 90.2 0.2 0.0 0.1 0.2 0.2 0.2 0.4 0.6 0.0 0.0 19.1 0.0 15.0 0.1 0.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.3 0.0 0.0 0.0 1.3 0.0 0.4 0.1 0.0 0.2 0.0 0.0 1.6 0.1 0.5 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.8 0.0 0.9 0.0 0.4 0.4 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.2 0.0 0.4 0.6 0.1 0.2 0.0 0.1 0.5 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.5 0.4 0.6 0.4 0.2 0.4 0.2 0.5 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.5 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.8 1.2 0.0 1.8 0.0 0.0 0.0 0.1 0.1 AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 134.3;liver: 180.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.7;Hepatocytes: 21.6;Late spermatids: 21.6;Proximal tubular cells: 38.5" "Group enriched" "Detected in all" 4 "liver cancer: 8.8;prostate cancer: 34.5;renal cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 175.4;U-266/84: 98.0" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 70000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" 8.6 15.0 5.9 5.0 5.5 3.0 6.4 4.6 6.0 6.5 4.6 40.0 18.0 4.7 9.6 15.6 6.2 20.5 10.1 5.4 7.8 134.3 180.6 9.2 3.6 5.9 6.4 7.8 13.8 13.0 5.7 7.7 6.6 39.3 42.9 12.0 60.7 12.5 19.2 4.9 15.9 7.0 5.8 5.4 34.8 4.3 8.4 4.8 8.3 14.9 5.6 8.8 8.5 5.8 12.7 20.2 11.1 14.3 7.7 11.9 19.1 16.6 12.2 7.6 5.7 66.1 15.1 4.1 8.7 23.6 28.6 5.8 2.8 12.0 7.7 12.7 10.9 9.8 13.7 19.0 5.4 6.0 3.0 18.1 6.0 9.7 3.6 10.7 8.5 8.3 3.8 14.7 22.4 9.6 5.0 7.6 10.0 9.4 32.9 6.0 18.6 6.5 33.2 62.4 6.1 8.7 27.6 19.3 16.9 9.1 14.9 5.9 15.6 24.6 5.4 6.2 13.6 175.4 98.0 7.4 7.0 12.1 18.8 0.3 6.0 9.3 8.3 8.0 7.0 7.1 7.2 6.4 8.9 5.2 6.6 4.8 10.0 8.7 14.2 4.6 7.9 6.0 5.9 5.5 4.6 6.0 5.4 7.8 5.9 6.4 6.6 5.8 8.4 5.8 0.8 3.2 4.1 0.0 2.2 0.4 0.4 0.9 1.8 4.3 1.4 0.9 1.1 8.6 3.7 1.8 0.0 1.0 2.2 19.7 5.9 0.8 8.9 2.3 1.2 3.0 4.2 2.1 0.0 3.8 1.0 2.9 4.1 1.5 0.0 1.2 1.1 21.6 1.1 5.0 0.0 5.1 4.1 0.9 0.2 21.6 0.6 1.2 0.0 0.0 1.5 9.3 3.1 0.0 0.0 2.6 4.5 2.2 1.6 0.6 4.7 38.5 3.1 0.9 0.0 1.7 3.7 0.7 0.7 3.4 0.6 0.3 1.5 1.2 4.4 0.4 AMBRA1 "DCAF3, FLJ20294, KIAA1736, WDR94" ENSG00000110497 "Autophagy and beclin 1 regulator 1" Q9C0C7 11 46396414-46594125 "Predicted intracellular proteins" "Autophagy, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 65.6;Excitatory neurons: 101.4;Inhibitory neurons: 101.9;Microglial cells: 84.3;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 11.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017825, HPA038535" Approved Approved Vesicles,Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Mitochondria "CAB017825: , HPA038535: AB_2676068" "unprognostic (1.76e-3)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (1.56e-1)" "unprognostic (6.00e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-3)" "unprognostic (7.78e-2)" "unprognostic (1.32e-1)" "unprognostic (1.98e-2)" "unprognostic (5.53e-3)" "unprognostic (2.32e-1)" "prognostic favorable (1.61e-4)" "unprognostic (2.90e-1)" "unprognostic (8.17e-2)" "unprognostic (1.61e-2)" "unprognostic (7.98e-2)" 10.2 16.4 7.5 6.7 9.1 11.6 10.5 7.8 9.1 10.4 7.4 10.1 10.0 11.7 5.8 10.6 10.1 6.4 8.4 7.9 6.4 8.2 9.1 8.6 8.2 6.6 6.1 11.6 8.3 12.3 9.2 7.6 7.3 9.8 7.0 7.8 10.6 7.6 13.0 17.4 9.8 8.8 5.4 10.3 9.7 12.6 8.4 13.5 9.4 8.3 8.1 9.4 10.0 10.8 8.7 23.0 15.5 16.8 16.1 12.0 9.6 8.5 16.1 13.6 14.1 17.4 14.8 17.5 8.5 15.1 16.1 15.4 7.9 15.0 10.0 15.3 25.5 11.9 14.6 22.5 10.5 17.3 14.6 16.7 11.6 8.6 16.3 14.8 14.3 14.9 20.8 11.7 10.2 21.4 22.2 12.2 26.1 19.6 12.4 21.5 21.3 9.7 13.1 15.4 12.5 13.9 14.7 16.6 15.6 10.1 17.2 11.6 15.2 12.5 11.1 14.6 12.8 13.2 11.3 18.1 11.1 9.6 11.3 11.8 2.2 1.7 2.6 1.1 2.2 2.4 1.9 2.0 2.0 2.1 1.9 1.7 2.5 1.4 1.9 2.1 3.2 1.9 7.5 9.1 7.8 9.1 7.9 6.4 6.6 6.1 7.3 5.4 8.4 10.8 5.1 3.2 5.6 65.6 7.2 4.1 2.5 3.4 4.0 6.6 5.1 5.2 8.2 4.3 4.3 0.0 2.1 4.0 5.9 16.0 0.0 6.9 13.8 5.2 5.3 4.7 9.6 10.3 101.4 9.3 2.1 6.7 13.7 8.3 4.5 8.8 3.6 4.1 5.2 5.0 101.9 9.7 2.0 3.5 2.3 6.7 5.3 4.8 5.4 84.3 3.1 3.2 6.2 84.9 136.4 8.4 7.5 7.9 6.6 3.5 8.2 3.2 4.4 5.7 13.1 4.2 5.8 2.1 2.1 7.4 4.5 6.8 6.4 7.9 6.4 4.2 AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 41.5;ovary: 33.1" "Group enriched" "Detected in some" 4 "granulocytes: 26.0;Granulosa cells: 36.1;Theca cells: 94.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "HEL: 40.1;K-562: 22.2" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 11 "hippocampal formation: 9.4" "HPA060228, HPA069636" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Cytosol" "HPA060228: AB_2684227, HPA069636: AB_2686163" "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" 0.6 41.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.1 0.5 0.0 0.3 0.0 0.9 0.4 0.0 0.0 0.2 33.1 12.5 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 4.2 0.1 0.1 0.0 0.0 5.7 0.7 9.1 0.5 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 40.1 0.0 0.8 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 22.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 3.5 2.6 0.0 0.1 1.5 0.0 4.2 0.1 2.1 0.1 2.7 0.0 0.1 26.0 36.1 11.4 0.3 0.1 0.0 0.0 0.0 0.0 1.2 0.0 2.5 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.1 0.3 0.0 0.0 0.3 0.8 94.9 0.1 0.0 AMMECR1 ENSG00000101935 "AMMECR nuclear protein 1" Q9Y4X0 X 110194186-110440318 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Alport syndrome, Deafness, Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 83.1;Excitatory neurons: 92.8;Inhibitory neurons: 108.7;Rod photoreceptor cells: 87.3;Syncytiotrophoblasts: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000590, HPA051762" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Mitochondria "HPA000590: AB_2666037, HPA051762: AB_2681596" "unprognostic (7.77e-2)" "unprognostic (1.93e-1)" "unprognostic (2.06e-1)" "unprognostic (5.17e-2)" "unprognostic (1.25e-1)" "unprognostic (6.87e-2)" "unprognostic (1.66e-3)" "unprognostic (6.55e-2)" "unprognostic (5.98e-2)" "prognostic favorable (6.62e-5)" "unprognostic (3.61e-2)" "unprognostic (3.96e-2)" "unprognostic (2.43e-3)" "unprognostic (3.33e-1)" "unprognostic (1.02e-1)" "prognostic favorable (8.44e-4)" "unprognostic (7.82e-2)" 3.6 2.9 1.7 3.7 1.7 13.4 3.4 1.8 2.0 2.9 8.5 3.7 3.1 2.3 2.1 7.9 3.3 2.3 1.1 1.5 1.7 3.4 3.3 2.8 4.2 1.3 1.3 5.5 2.0 2.2 2.0 7.0 1.2 2.2 3.9 14.5 2.8 1.9 1.3 7.4 3.3 2.9 1.0 3.7 3.7 1.6 1.7 4.5 2.4 1.7 5.7 4.8 4.5 1.5 20.3 9.8 7.1 3.4 7.9 11.8 7.8 13.8 12.3 11.1 16.2 15.9 14.4 12.0 6.4 18.4 9.0 9.5 22.7 15.7 11.3 8.4 10.1 16.7 21.7 3.3 19.9 13.5 6.7 6.6 27.3 12.7 22.6 6.0 8.9 5.9 47.1 34.8 8.5 17.2 6.5 4.8 32.6 17.4 19.1 13.7 7.6 21.2 18.8 16.8 11.3 5.3 23.2 22.7 19.9 8.5 5.6 13.3 4.1 7.6 4.6 22.8 12.6 7.1 8.6 18.9 11.6 27.5 25.9 0.6 0.9 0.8 1.6 0.6 2.1 1.6 3.2 2.6 1.5 2.2 2.1 1.9 0.4 0.6 2.7 0.6 2.3 1.0 1.7 1.7 1.8 2.0 1.5 1.7 1.3 1.3 1.2 1.0 1.7 1.5 4.4 0.0 9.8 17.9 11.5 9.6 3.9 10.5 5.7 35.3 7.5 4.4 4.2 8.6 8.9 3.7 52.1 27.2 9.5 8.9 23.5 9.2 0.5 10.5 7.7 9.6 15.0 83.1 92.8 12.0 9.9 12.8 13.7 13.4 2.5 14.4 19.6 8.4 7.1 1.7 108.7 11.2 12.2 7.6 3.1 2.1 12.8 7.3 3.6 21.5 9.4 7.1 14.4 35.7 19.2 11.5 3.7 17.3 8.0 9.1 10.3 10.2 10.4 87.3 13.1 6.7 8.4 2.2 6.9 17.4 26.7 86.5 13.0 34.7 10.5 15.7 ANGEL1 "Ccr4e, KIAA0759" ENSG00000013523 "Angel homolog 1" Q9UNK9 14 76786009-76826246 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Late spermatids: 75.1;Oligodendrocyte precursor cells: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000948 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA000948: AB_2227189" "unprognostic (4.81e-2)" "unprognostic (2.37e-2)" "unprognostic (2.67e-1)" "unprognostic (2.46e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-1)" "unprognostic (7.33e-2)" "prognostic favorable (3.43e-4)" "unprognostic (9.24e-2)" "unprognostic (1.01e-1)" "prognostic favorable (5.46e-4)" "unprognostic (3.03e-1)" "unprognostic (6.92e-3)" "unprognostic (1.42e-1)" "unprognostic (2.22e-1)" "unprognostic (1.53e-1)" "unprognostic (6.32e-2)" 11.3 18.5 18.3 11.8 19.7 6.8 12.7 16.7 21.2 12.8 15.6 10.0 9.2 14.8 23.8 7.0 12.2 11.4 15.7 19.2 21.1 11.6 19.3 14.0 12.2 22.5 19.6 19.3 50.8 17.2 21.1 10.4 21.5 9.3 10.9 26.4 15.8 8.4 12.2 6.4 10.3 12.3 18.1 29.3 15.8 52.4 20.1 8.1 13.7 9.8 10.9 9.5 8.5 23.8 13.1 14.0 15.2 13.6 12.2 11.1 14.1 7.7 11.0 7.8 9.9 13.5 18.2 23.8 11.1 6.7 10.6 16.2 14.6 13.7 13.1 10.1 13.1 14.8 9.7 10.3 7.9 7.8 8.7 11.8 16.8 7.3 14.5 11.3 20.0 24.8 14.5 6.2 8.2 25.3 14.0 11.6 17.5 20.7 18.4 17.0 10.4 14.1 11.8 18.4 21.5 9.6 11.6 15.8 7.1 13.8 31.1 8.4 9.6 9.1 8.0 6.9 6.4 15.9 12.9 14.7 7.7 13.7 11.8 0.8 4.8 1.6 5.9 5.5 7.2 6.8 5.3 5.6 7.5 5.5 7.5 5.6 1.4 5.5 7.1 4.9 4.5 5.9 18.3 19.7 16.7 21.2 19.2 21.1 22.5 19.6 21.5 18.1 20.1 23.8 7.4 6.4 10.5 17.6 4.7 1.1 1.8 1.5 2.2 2.4 5.7 5.0 6.7 5.7 2.2 3.7 10.4 1.5 1.5 2.1 0.0 3.3 64.3 3.7 3.9 10.0 4.2 4.2 18.3 3.2 2.8 4.3 1.5 3.3 1.3 15.9 7.1 9.5 7.2 0.0 19.7 4.4 4.1 5.7 2.0 75.1 2.1 5.5 1.8 23.4 1.4 4.9 1.0 64.8 30.2 2.5 1.0 4.9 8.9 3.4 1.7 1.3 1.4 8.9 6.6 5.1 2.4 15.9 4.9 2.8 0.4 1.2 3.0 12.9 4.6 1.5 ANGPTL1 "ANG3, ANGPT3, AngY, ARP1" ENSG00000116194 "Angiopoietin like 1" O95841 1 178849535-178871077 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 133.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 81.7;Leydig cells: 425.9;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "ASC diff: 149.9;ASC TERT1: 60.1;HHSteC: 64.9;HSkMC: 147.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009976 Approved "Secreted to blood" NA NA 380000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009976: AB_1844822" "unprognostic (2.59e-2)" "unprognostic (1.31e-1)" "unprognostic (5.80e-3)" "unprognostic (2.63e-2)" "unprognostic (3.60e-1)" "unprognostic (1.71e-2)" "prognostic favorable (8.73e-4)" "unprognostic (3.81e-2)" "unprognostic (5.78e-3)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (5.31e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.49e-2)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.61e-3)" 56.6 45.1 2.0 10.5 2.7 0.9 26.9 2.3 2.7 21.3 1.5 56.7 9.6 69.2 14.0 33.8 59.0 27.9 22.8 2.9 1.9 17.5 23.9 12.6 3.5 2.1 1.5 68.2 21.9 1.1 2.1 133.8 1.4 12.3 27.5 9.6 36.3 9.5 30.3 9.0 26.7 65.5 2.2 10.9 21.6 15.6 1.7 8.6 41.1 57.3 6.9 23.9 17.1 2.3 0.2 0.0 4.0 0.0 149.9 60.1 0.0 0.1 0.0 0.4 0.8 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 64.9 0.0 0.1 147.5 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.9 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 2.7 2.3 2.7 2.9 1.9 2.1 1.5 1.4 2.2 1.7 2.3 16.5 0.0 0.0 9.4 1.3 3.7 0.0 0.0 1.2 2.3 0.8 0.5 3.7 41.5 0.0 1.8 6.2 0.6 0.1 0.0 1.9 2.4 1.4 3.3 40.3 4.1 0.0 0.0 14.8 0.4 0.4 81.7 1.1 5.5 0.0 1.6 8.9 1.0 1.4 0.0 14.9 0.0 0.0 0.0 4.6 10.6 425.9 0.8 3.6 8.4 0.0 31.6 0.0 21.6 0.7 0.0 5.0 212.1 0.4 0.1 0.1 0.1 0.7 10.9 39.5 10.0 51.8 0.8 0.6 0.2 3.7 1.4 0.5 2.7 0.0 0.1 ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Group enriched" "Detected in many" 4 "Astrocytes: 1101.2;Bipolar cells: 376.6;Cone photoreceptor cells: 479.6;Excitatory neurons: 1282.0;Horizontal cells: 1431.8;Inhibitory neurons: 1060.7;Oligodendrocyte precursor cells: 497.1;Oligodendrocytes: 1351.0;Rod photoreceptor cells: 484.4" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 29.2;ASC TERT1: 32.2;RH-30: 49.6;SH-SY5Y: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" 31.0 13.6 94.9 11.2 109.0 0.1 18.3 63.1 165.7 31.6 0.0 30.1 8.5 15.8 5.9 12.9 9.6 22.5 119.5 103.9 77.5 110.1 2.4 7.2 9.2 130.2 61.1 27.3 3.2 1.2 19.3 2.1 119.5 7.8 11.4 191.2 6.7 13.3 171.7 8.7 12.7 24.9 51.9 28.3 8.3 9.4 84.8 4.4 9.6 150.5 7.2 9.5 12.3 116.2 0.1 2.9 18.7 5.2 29.2 32.2 0.1 1.5 3.4 0.9 2.6 4.2 0.0 6.9 2.1 5.9 4.1 0.1 11.0 0.6 1.0 2.3 7.3 4.0 0.0 2.9 1.7 1.9 1.2 15.2 3.0 1.2 6.0 3.9 0.0 0.4 0.0 9.3 5.8 0.3 0.2 0.1 9.4 0.1 2.0 0.7 49.6 0.0 0.2 0.0 13.6 24.1 0.2 0.7 8.1 11.7 0.1 1.1 0.0 4.7 2.2 0.4 3.0 6.8 1.8 0.9 20.1 0.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 109.0 63.1 165.7 103.9 77.5 130.2 61.1 119.5 51.9 84.8 116.2 6.9 0.0 3.9 1101.2 1.1 10.5 0.0 0.0 1.8 376.6 0.2 0.6 188.5 0.0 1.3 20.2 479.6 0.1 0.0 0.0 15.6 0.0 111.2 36.4 6.0 6.4 66.0 0.0 1282.0 1.6 0.1 79.0 2.0 7.2 1.3 81.8 0.0 0.4 1.0 1431.8 1060.7 0.4 8.2 0.0 19.7 49.8 36.4 2.9 17.8 90.9 0.6 44.5 0.0 497.1 1351.0 0.1 5.0 30.1 0.9 0.4 0.1 127.9 0.8 484.4 6.6 24.3 26.5 2.3 1.5 0.8 9.5 0.0 1.9 2.6 0.3 0.2 ANKRD10 FLJ20093 ENSG00000088448 "Ankyrin repeat domain 10" Q9NXR5 13 110878540-110915069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034211, HPA038878, HPA038879" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB034211: AB_2058024, HPA038878: AB_2676252, HPA038879: AB_2676253" "unprognostic (3.29e-2)" "unprognostic (2.38e-1)" "unprognostic (9.26e-2)" "unprognostic (1.06e-1)" "unprognostic (2.89e-3)" "unprognostic (2.49e-1)" "unprognostic (4.97e-3)" "unprognostic (9.60e-2)" "unprognostic (1.16e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "unprognostic (2.92e-2)" "prognostic unfavorable (1.25e-6)" "unprognostic (1.95e-1)" "unprognostic (2.68e-1)" "unprognostic (8.32e-2)" "prognostic favorable (6.41e-6)" 78.2 60.3 61.9 42.2 69.8 88.7 75.6 65.9 85.2 109.1 71.4 97.2 43.8 87.4 89.9 37.6 90.7 53.5 74.3 62.6 68.8 93.9 84.1 91.7 63.3 72.5 65.8 99.6 94.9 25.5 97.5 36.4 75.5 108.1 50.2 77.6 70.3 42.4 176.6 48.9 88.1 49.0 66.3 138.9 75.0 40.8 67.7 52.4 82.1 73.4 50.4 79.2 68.3 80.1 36.1 29.6 66.7 56.2 50.2 48.4 29.6 24.0 50.0 23.5 28.9 31.0 68.8 49.5 51.1 18.2 38.2 81.1 29.2 22.6 31.7 119.1 43.2 59.0 73.3 64.9 20.0 85.9 49.4 46.2 33.7 16.5 24.4 49.1 32.1 48.8 26.4 33.1 64.2 10.8 49.9 95.3 37.0 79.1 18.3 76.0 24.5 49.6 64.9 39.4 53.2 39.7 18.2 31.7 39.9 49.7 22.7 108.0 28.0 27.6 23.0 13.7 24.7 40.8 46.9 28.9 51.7 41.5 44.2 39.0 25.8 22.7 30.4 21.1 26.3 42.9 29.2 25.3 33.8 44.7 30.9 33.7 16.1 31.8 22.3 31.5 39.9 26.8 61.9 69.8 65.9 85.2 62.6 68.8 72.5 65.8 75.5 66.3 67.7 80.1 77.6 16.0 65.4 83.6 69.3 94.3 39.0 25.9 129.1 33.3 72.2 55.0 32.0 45.8 45.3 38.6 54.2 45.1 54.4 43.4 19.6 52.1 8.5 59.0 79.2 83.3 41.9 30.3 118.7 49.2 51.8 78.3 51.5 105.4 30.4 65.3 40.7 48.8 46.6 32.0 105.8 55.2 57.0 46.5 99.7 7.3 39.1 60.4 72.9 145.2 44.7 28.6 35.0 158.3 203.6 38.7 46.2 51.6 58.5 62.5 40.9 45.1 40.8 55.4 52.6 105.6 88.8 28.0 23.6 44.3 77.7 38.9 58.9 44.9 59.6 53.2 ANKRD16 DKFZP434N1511 ENSG00000134461 "Ankyrin repeat domain 16" Q6P6B7 10 5861616-5889906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 26.9;Inhibitory neurons: 28.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037920, HPA037921" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA037920: AB_10671381, HPA037921: AB_2675740" "unprognostic (1.90e-1)" "unprognostic (1.67e-1)" "unprognostic (5.94e-3)" "unprognostic (2.15e-1)" "unprognostic (1.73e-2)" "unprognostic (6.18e-3)" "unprognostic (9.96e-3)" "unprognostic (4.57e-2)" "unprognostic (3.05e-1)" "unprognostic (1.86e-2)" "prognostic favorable (1.98e-4)" "unprognostic (5.85e-2)" "prognostic unfavorable (4.31e-7)" "unprognostic (1.06e-2)" "unprognostic (7.64e-2)" "unprognostic (9.53e-2)" "unprognostic (3.93e-2)" 3.8 4.0 5.5 2.3 5.5 1.9 4.1 5.6 7.9 6.3 3.1 3.7 3.2 5.1 4.9 3.7 5.8 2.5 3.3 5.2 4.2 3.5 4.1 3.0 3.1 5.0 4.5 6.2 4.1 5.7 3.9 1.7 5.2 4.1 2.5 4.4 4.0 3.1 3.9 6.7 3.2 3.2 4.0 3.2 6.6 8.7 4.8 3.8 3.7 2.6 3.3 4.3 4.4 5.6 8.3 9.8 4.5 9.2 4.6 3.4 6.6 2.5 1.9 4.4 3.8 12.1 4.3 8.8 3.5 4.2 1.6 8.5 5.5 6.4 2.0 3.1 8.6 5.5 4.8 11.1 5.9 3.4 3.8 5.3 4.8 4.0 3.1 3.5 4.9 9.0 7.5 2.6 3.1 11.5 12.7 5.8 3.7 11.2 6.9 9.6 2.9 18.1 5.0 5.3 2.7 6.0 5.2 6.4 6.0 3.6 8.9 6.9 3.2 2.6 3.4 5.8 3.5 14.7 7.1 5.8 5.4 3.3 2.9 0.3 0.2 0.0 0.1 0.1 0.1 0.3 0.1 0.2 0.2 0.4 0.4 0.1 0.1 0.4 0.1 0.5 0.2 0.1 5.5 5.5 5.6 7.9 5.2 4.2 5.0 4.5 5.2 4.0 4.8 5.6 5.3 3.2 1.3 14.7 5.9 4.7 7.8 1.4 4.6 14.1 7.0 6.0 2.8 10.0 1.8 3.7 6.2 4.7 3.0 2.4 13.7 2.1 8.4 7.8 9.8 4.2 4.2 5.5 25.1 2.2 3.6 10.2 4.1 4.4 0.0 13.0 3.3 3.8 3.3 26.9 28.4 3.1 0.0 1.0 3.3 14.6 5.6 3.2 3.6 5.6 3.6 8.8 1.0 12.5 16.2 1.0 1.3 3.8 11.3 7.3 5.2 8.3 1.0 14.4 0.0 8.5 4.5 13.0 7.8 6.5 5.7 1.5 3.5 10.5 5.2 3.7 ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 181.7;salivary gland: 180.5;seminal vesicle: 209.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 70.2;Early spermatids: 54.9;Hepatocytes: 141.3;Late spermatids: 75.1;Sertoli cells: 46.0;Smooth muscle cells: 52.5;Suprabasal keratinocytes: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 140.2;CAPAN-2: 207.9;HaCaT: 254.0;OE19: 182.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 6.6" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" 16.3 2.2 0.3 3.6 1.6 0.1 86.8 0.8 1.3 46.7 0.1 14.3 3.6 40.0 181.7 12.7 59.1 54.4 21.9 0.5 0.1 6.4 108.5 16.1 3.4 1.0 0.2 2.9 9.1 48.0 4.4 5.2 1.1 17.1 11.0 0.9 180.5 209.2 12.7 97.4 4.6 30.1 0.2 1.2 48.3 10.4 0.1 1.5 35.4 33.0 4.0 6.7 12.8 0.5 140.2 5.3 0.3 4.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 207.9 0.0 2.5 0.0 0.3 254.0 0.0 0.7 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.0 1.0 0.5 0.3 1.1 182.2 19.6 0.3 0.0 0.7 0.0 0.2 7.3 0.2 0.1 43.1 0.8 1.4 16.2 0.5 0.5 0.3 1.1 0.0 3.5 0.1 0.3 0.2 0.2 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.8 1.3 0.5 0.1 1.0 0.2 1.1 0.2 0.1 0.5 7.2 0.0 0.0 0.7 0.4 17.7 21.5 4.2 0.0 0.0 30.5 70.2 3.5 17.2 2.0 0.0 0.0 1.3 0.2 0.4 0.0 4.1 54.9 10.0 27.5 5.6 0.0 2.7 0.7 0.0 0.6 4.2 36.7 18.5 4.5 0.0 3.3 141.3 0.2 0.0 20.4 13.3 0.0 1.6 3.0 75.1 1.8 0.7 5.4 2.8 0.0 0.8 0.0 1.5 0.7 1.0 0.5 1.5 0.3 22.6 0.0 0.7 0.3 0.4 46.0 1.1 52.5 1.4 2.3 1.4 46.7 4.1 0.7 0.1 0.4 20.9 ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 226.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 81.3;Early spermatids: 57.3;Late spermatids: 283.2;Microglial cells: 143.4;Rod photoreceptor cells: 179.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.6;HUVEC TERT2: 9.5;U-2 OS: 24.1" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 9: U-2 OS - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" 8.8 0.3 3.8 0.4 4.4 0.0 6.6 2.2 3.3 4.3 5.0 1.9 0.7 1.8 1.4 1.7 3.2 1.1 8.0 2.5 2.4 1.2 0.2 7.2 0.1 3.2 3.2 1.5 0.9 1.3 0.6 4.1 3.4 2.5 0.6 226.0 1.3 1.0 2.0 1.1 1.7 1.5 3.0 3.4 2.2 10.1 3.9 0.3 2.4 4.4 0.2 2.4 3.5 2.8 2.5 0.0 4.4 0.0 0.0 0.2 2.0 0.0 9.6 0.5 1.0 0.0 0.2 0.2 0.3 0.0 0.1 0.3 0.0 0.1 0.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 1.9 0.0 1.0 0.0 0.0 4.6 2.3 0.0 1.9 0.0 1.0 0.1 0.1 0.0 0.0 2.3 1.6 0.0 3.9 1.3 0.0 0.2 0.0 24.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 4.4 2.2 3.3 2.5 2.4 3.2 3.2 3.4 3.0 3.9 2.8 9.7 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.6 11.5 0.3 0.1 1.9 0.0 0.0 0.0 81.3 1.4 0.0 0.0 0.0 0.0 57.3 0.4 0.4 9.1 0.0 0.0 1.7 0.0 2.0 0.3 0.0 0.5 0.0 0.0 4.6 0.0 0.2 10.1 2.0 0.0 0.0 0.0 0.0 283.2 0.3 0.1 0.0 143.4 0.0 13.0 0.0 31.2 9.9 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 179.9 0.0 1.3 0.6 1.4 1.8 0.0 0.1 2.5 0.0 0.2 0.2 0.0 ANO5 "GDD1, LGMD2L, TMEM16E" ENSG00000171714 "Anoctamin 5" Q75V66 11 21799934-22283357 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 24.9;parathyroid gland: 17.0;skeletal muscle: 65.5;tongue: 50.4" "Group enriched" "Detected in many" 7 "Astrocytes: 67.9;Cardiomyocytes: 86.2;Excitatory neurons: 166.6;Inhibitory neurons: 136.4;Oligodendrocyte precursor cells: 81.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.9;HAP1: 5.0;HEK 293: 6.6;NTERA-2: 3.5;RPTEC TERT1: 3.2;U-266/84: 3.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058857 Uncertain NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058857: AB_2683835" "unprognostic (5.25e-3)" "unprognostic (1.36e-3)" "unprognostic (2.43e-1)" "unprognostic (7.67e-3)" "unprognostic (3.50e-2)" "unprognostic (5.85e-2)" "unprognostic (8.17e-3)" "unprognostic (2.30e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.54e-4)" "unprognostic (8.55e-2)" "prognostic favorable (2.50e-7)" "unprognostic (3.65e-3)" "unprognostic (2.84e-1)" "unprognostic (2.77e-4)" "unprognostic (7.94e-2)" 0.9 4.5 1.9 0.8 3.0 0.0 0.7 0.1 8.9 1.6 3.0 2.6 3.3 1.5 1.3 2.0 0.8 1.7 24.9 4.0 2.2 3.6 2.1 1.2 0.2 2.7 2.1 0.5 3.9 17.0 3.4 0.0 2.2 4.2 3.3 2.1 2.6 4.1 65.5 0.1 2.5 2.7 0.4 0.7 3.0 1.8 2.4 0.2 4.7 50.4 0.3 2.0 0.3 3.4 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.3 1.4 2.5 0.0 0.0 0.0 0.0 3.5 2.6 0.0 0.0 0.0 0.0 3.2 0.1 2.7 2.6 0.0 0.0 0.0 2.1 2.1 1.9 0.0 0.0 1.9 0.0 0.0 2.0 3.7 0.0 2.8 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 3.0 0.1 8.9 4.0 2.2 2.7 2.1 2.2 0.4 2.4 3.4 0.4 0.0 5.9 67.9 0.6 0.3 0.3 0.0 0.0 6.7 2.2 0.6 86.2 1.5 0.0 1.8 0.0 0.1 0.0 7.8 1.9 1.3 5.8 0.4 0.2 3.2 5.4 0.4 166.6 2.7 0.0 3.0 1.5 0.3 0.0 3.0 2.5 5.1 0.5 1.7 136.4 7.1 0.0 0.6 1.4 2.9 0.0 1.6 1.8 14.0 1.9 2.8 0.0 81.4 4.2 1.0 4.4 1.2 0.0 1.4 2.7 3.3 0.7 0.8 0.0 8.1 2.4 11.0 0.9 0.1 0.1 0.0 0.2 1.6 4.6 0.2 ANOS1 "ADMLX, KAL, KAL1, KALIG-1, WFDC19" ENSG00000011201 "Anosmin 1" P23352 X 8528874-8732137 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.1" "Cell type enriched" "Detected in many" 11 "Alveolar cells type 1: 240.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 40.4;NTERA-2: 37.0;U-2 OS: 17.6" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.93e-1)" "unprognostic (5.33e-2)" "unprognostic (9.54e-2)" "unprognostic (4.16e-3)" "unprognostic (7.77e-3)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" "unprognostic (1.17e-3)" "unprognostic (4.53e-2)" "unprognostic (6.43e-2)" "unprognostic (2.09e-2)" "unprognostic (6.24e-2)" "unprognostic (1.71e-2)" "unprognostic (9.38e-3)" "unprognostic (6.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.56e-2)" 6.6 4.0 7.6 1.1 10.5 0.3 3.7 6.0 7.3 4.4 0.9 0.6 0.3 0.5 3.1 1.3 1.1 1.7 5.0 8.3 12.2 0.8 0.8 43.1 1.9 13.8 11.5 0.3 0.4 15.1 0.5 1.2 14.8 4.1 1.0 19.6 2.4 4.4 10.5 3.1 0.6 0.7 18.6 0.8 0.8 3.9 12.6 4.0 9.3 6.8 0.9 1.2 1.2 17.9 0.1 0.0 1.9 0.0 0.0 0.0 2.2 0.8 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.7 4.0 0.2 5.5 0.5 5.6 0.0 0.0 0.0 1.5 0.1 3.1 0.3 0.1 40.4 0.0 0.1 0.0 0.0 0.5 0.4 0.3 0.0 37.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 2.1 0.1 1.9 0.5 0.0 4.8 0.0 1.0 0.0 0.0 17.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 10.5 6.0 7.3 8.3 12.2 13.8 11.5 14.8 18.6 12.6 17.9 1.7 240.4 12.6 0.0 0.0 0.0 4.7 0.0 13.1 20.5 6.2 3.4 6.2 0.0 19.8 0.0 4.2 0.1 0.0 0.0 0.0 0.9 0.2 0.4 1.5 1.6 0.0 0.0 0.0 0.0 0.3 10.9 0.0 0.1 1.3 2.2 6.1 0.0 5.1 0.0 0.0 0.0 0.0 2.9 0.0 0.3 0.6 3.0 0.0 0.0 0.2 17.8 0.0 0.0 0.0 1.5 0.1 1.2 0.0 3.1 0.0 0.2 3.6 1.6 0.0 8.7 3.3 0.6 1.6 1.5 0.0 0.1 0.3 0.8 0.4 1.1 ANXA9 ANX31 ENSG00000143412 "Annexin A9" O76027 1 150982249-150995634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 61.5;Collecting duct cells: 12.9;Ductal cells: 21.2;Hepatocytes: 17.4;Proximal tubular cells: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.6" "Group enriched" "Detected in many" 4 "dendritic cells: 1.6;granulocytes: 1.0;monocytes: 1.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 40.6;Hep G2: 42.3;MCF7: 59.2;OE19: 47.8;T-47d: 139.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028404, HPA028698" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Cytosol" "HPA028404: AB_10599190, HPA028698: AB_10600227" "unprognostic (4.06e-1)" "unprognostic (1.55e-2)" "unprognostic (3.15e-3)" "unprognostic (2.08e-3)" "unprognostic (2.93e-2)" "unprognostic (4.49e-2)" "unprognostic (1.84e-2)" "unprognostic (3.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "unprognostic (2.97e-1)" "prognostic favorable (8.74e-6)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (8.99e-2)" "unprognostic (1.72e-2)" 3.2 3.7 2.6 2.6 7.1 2.4 6.9 6.1 3.5 2.2 3.3 2.1 4.6 6.4 5.9 26.2 4.7 9.2 6.0 1.7 3.5 22.0 29.9 3.1 2.3 9.0 6.7 4.7 35.8 19.2 1.2 1.0 7.9 2.4 0.3 7.2 7.5 21.2 3.8 32.4 4.2 2.9 4.5 2.8 4.2 3.8 5.3 0.5 25.0 0.2 23.2 6.3 6.0 12.1 11.7 2.8 4.2 4.4 0.0 0.0 11.4 1.0 0.8 0.1 0.0 33.9 40.6 0.4 2.5 0.0 1.3 6.8 0.0 0.8 0.1 3.9 4.4 6.1 4.7 42.3 0.0 2.4 2.6 0.0 0.3 0.1 0.2 9.5 0.0 1.8 3.0 13.2 0.1 59.2 0.5 3.2 1.1 47.8 0.8 2.8 0.6 15.0 0.1 17.0 6.4 3.6 2.6 28.8 1.7 2.3 139.9 3.7 4.7 0.9 1.3 0.7 0.8 4.0 13.0 18.8 6.2 4.2 3.3 0.0 1.2 0.7 0.0 0.7 0.3 0.2 0.1 0.2 1.6 0.0 0.3 0.0 1.0 0.0 0.1 0.0 0.0 0.4 2.6 7.1 6.1 3.5 1.7 3.5 9.0 6.7 7.9 4.5 5.3 12.1 0.1 0.0 1.1 0.3 0.2 0.1 0.4 0.8 0.0 0.0 4.5 2.5 0.4 61.5 4.5 12.9 0.0 2.0 0.1 0.0 3.9 21.2 1.5 1.3 0.8 0.1 0.0 0.0 0.2 7.5 0.3 0.6 0.0 1.6 1.3 0.0 0.0 17.4 2.2 0.0 0.2 0.0 0.0 0.6 0.4 0.9 1.5 1.4 1.8 0.0 0.2 0.0 0.0 1.0 0.5 2.9 0.1 1.2 0.0 0.3 0.3 44.6 2.5 0.0 0.0 0.1 0.3 4.9 0.2 0.3 0.0 1.5 0.2 0.0 0.3 5.4 AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 162.0;Proximal tubular cells: 373.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.6" "Cell line enhanced" "Detected in many" "CACO-2: 172.8;Hep G2: 313.8;MCF7: 268.3;OE19: 156.7;RT4: 164.9;U-2 OS: 166.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA054999 Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA054999: AB_2682666" "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" 3.4 0.1 0.8 6.4 0.3 0.9 32.9 0.6 0.8 27.1 0.3 67.1 64.0 6.6 61.8 51.9 46.6 22.7 0.4 0.5 0.4 76.3 1.5 19.2 0.4 0.7 0.6 0.3 55.9 62.4 34.8 16.2 0.4 30.8 63.4 0.1 41.5 24.0 0.3 42.1 54.8 3.0 0.3 0.6 59.1 9.6 0.7 4.2 58.8 0.3 9.5 23.4 19.1 0.6 144.2 71.1 0.4 10.4 0.0 0.0 65.0 0.2 0.0 2.3 1.6 172.8 82.1 0.4 64.7 1.2 43.4 97.6 0.1 109.0 3.2 0.6 1.0 6.7 48.5 313.8 1.3 0.3 0.8 0.2 81.6 3.9 0.1 5.0 0.0 0.4 0.3 0.6 1.2 268.3 0.6 1.8 31.4 156.7 0.0 2.4 9.3 0.7 2.7 164.9 67.3 0.2 0.0 120.0 0.6 34.6 123.3 0.4 0.0 0.4 166.7 0.9 2.2 0.4 0.9 1.4 0.2 0.4 0.2 4.3 0.4 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.6 0.0 1.4 0.2 0.0 2.7 0.8 0.3 0.6 0.8 0.5 0.4 0.7 0.6 0.4 0.3 0.7 0.6 0.4 28.9 34.8 0.0 1.9 6.9 19.2 68.9 13.1 0.0 49.3 30.0 0.5 47.1 64.2 86.5 0.0 123.0 0.5 112.2 137.0 141.3 43.4 52.4 5.4 1.7 74.4 0.0 0.3 115.8 101.0 1.5 73.4 57.7 2.5 0.0 0.7 0.0 9.8 0.0 0.2 95.5 97.6 0.8 0.0 19.9 1.5 2.6 3.6 0.0 1.7 0.0 0.0 0.0 0.2 130.2 125.6 0.7 0.0 37.6 162.0 373.6 61.5 0.0 0.0 0.0 6.2 16.9 4.1 39.1 13.1 66.1 2.8 0.0 131.4 48.3 AP1S1 "AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2" ENSG00000106367 "Adaptor related protein complex 1 subunit sigma 1" P61966 7 101154456-101161596 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Ichthyosis, Mental retardation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 344.4;Proximal enterocytes: 241.3;Proximal tubular cells: 304.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060945 Supported Supported "Golgi apparatus,Vesicles" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" "HPA060945: AB_2684393" "unprognostic (1.98e-2)" "unprognostic (5.41e-3)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-3)" "unprognostic (8.70e-3)" "unprognostic (7.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.76e-1)" "unprognostic (7.79e-2)" "unprognostic (1.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" 14.4 24.6 72.2 13.9 75.7 5.8 17.2 43.7 82.6 18.3 34.6 28.6 39.0 16.9 17.0 34.2 13.8 12.8 11.8 85.2 59.6 41.2 36.2 14.7 11.9 53.6 51.9 13.5 21.9 22.8 31.0 15.9 53.4 22.2 22.4 14.6 20.3 9.3 6.4 39.2 30.3 12.7 46.1 20.2 22.0 16.4 62.5 19.1 15.2 8.5 13.6 20.1 19.5 62.7 121.0 87.3 63.3 118.4 42.8 70.4 138.2 76.8 51.1 50.8 52.8 47.3 147.5 24.9 127.5 84.6 97.1 59.0 35.3 116.0 45.6 57.0 56.6 16.8 52.0 61.4 54.2 46.8 87.7 79.1 91.0 49.4 20.6 76.7 76.8 54.1 56.7 103.2 129.9 292.1 40.4 107.8 97.8 177.0 188.2 24.9 27.2 54.6 127.8 88.8 47.5 157.7 40.4 121.1 151.4 101.6 50.7 46.8 79.0 74.1 132.3 27.6 55.2 21.4 51.4 48.4 195.2 50.1 152.9 0.5 3.3 0.3 2.3 3.1 2.2 2.6 3.2 2.5 4.6 2.0 1.9 1.8 1.2 1.3 1.8 5.0 3.3 2.4 72.2 75.7 43.7 82.6 85.2 59.6 53.6 51.9 53.4 46.1 62.5 62.7 34.4 6.4 0.0 2.3 17.9 38.7 29.7 173.0 46.7 30.7 54.8 49.0 1.1 45.8 72.9 55.2 8.4 170.7 19.8 88.4 344.4 128.2 2.5 28.8 34.2 36.7 90.3 16.2 21.2 111.7 101.3 27.7 42.8 31.9 5.7 85.3 28.9 43.0 95.2 30.3 10.3 96.5 116.0 24.8 21.6 3.4 35.1 27.3 53.4 7.5 58.0 34.1 17.5 2.5 9.8 183.3 86.1 21.8 17.4 34.9 241.3 304.8 34.9 22.3 19.7 11.4 38.4 13.1 70.9 51.4 45.5 60.5 19.5 157.4 119.9 38.2 AP5Z1 "KIAA0415, SPG48, zeta" ENSG00000242802 "Adaptor related protein complex 5 subunit zeta 1" O43299 7 4775615-4794397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035693 Supported Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Nucleoplasm "HPA035693: AB_10960687" "unprognostic (1.64e-1)" "unprognostic (5.22e-2)" "unprognostic (3.01e-3)" "unprognostic (4.24e-2)" "unprognostic (2.43e-3)" "unprognostic (5.19e-1)" "prognostic unfavorable (1.35e-5)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-3)" "unprognostic (1.26e-2)" "unprognostic (5.32e-3)" "unprognostic (8.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.95e-2)" "unprognostic (2.22e-1)" 14.8 18.5 7.0 0.7 7.1 1.5 11.8 7.3 10.0 12.4 5.8 13.2 1.1 13.4 1.0 11.0 11.0 0.8 7.7 6.9 5.7 9.2 9.2 12.9 1.8 8.3 6.5 11.8 9.9 0.7 9.8 1.1 7.4 11.7 0.4 0.6 12.4 0.7 8.5 21.8 15.5 0.4 5.9 22.9 12.0 8.6 7.4 0.9 11.2 0.2 0.6 13.4 10.9 7.3 2.8 4.2 0.7 2.4 1.0 0.9 4.3 1.3 1.9 2.0 1.7 5.2 3.5 1.6 1.8 0.9 5.1 5.4 0.7 0.5 0.6 1.8 3.5 2.4 4.5 4.6 3.0 2.5 5.1 2.2 1.6 1.8 1.3 0.7 0.5 2.2 3.4 1.1 1.2 7.7 0.3 15.0 5.9 0.3 4.3 2.9 2.6 4.8 1.0 4.4 1.7 3.0 1.8 8.7 6.4 0.5 6.4 8.9 3.8 2.3 4.4 6.5 1.7 8.5 7.4 2.3 1.7 5.6 3.6 1.9 2.3 2.9 2.4 2.8 1.4 1.9 1.8 2.4 1.2 1.8 2.5 2.2 2.2 2.4 2.5 2.4 1.8 1.3 7.0 7.1 7.3 10.0 6.9 5.7 8.3 6.5 7.4 5.9 7.4 7.3 12.4 9.6 15.0 7.5 18.2 6.9 2.9 8.8 8.0 10.5 5.7 5.8 4.3 15.7 6.6 11.0 4.2 11.5 20.3 20.1 0.0 14.1 2.2 9.9 10.1 11.6 12.0 5.0 12.4 13.6 7.7 9.9 21.4 16.4 17.1 14.3 12.5 8.1 28.7 18.5 10.7 15.1 10.2 12.3 10.7 1.5 13.4 16.3 14.2 13.1 23.4 8.2 21.6 10.6 12.6 20.6 15.9 10.9 19.8 4.9 14.7 6.8 8.3 9.4 0.0 5.8 9.5 8.1 10.8 7.6 11.1 16.6 15.6 12.6 14.1 3.8 APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000363-55009057 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: AB_2680448" "unprognostic (2.90e-2)" "prognostic favorable (6.17e-4)" "unprognostic (4.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (5.62e-2)" "prognostic unfavorable (6.13e-7)" "unprognostic (5.89e-2)" "unprognostic (4.87e-2)" "prognostic favorable (5.21e-4)" "unprognostic (7.46e-2)" "unprognostic (3.16e-1)" "unprognostic (6.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.63e-4)" 7.2 8.9 6.1 8.8 6.3 10.0 7.2 6.0 6.6 7.6 6.5 8.9 8.9 7.4 8.5 15.5 7.3 6.3 9.0 5.9 6.4 10.8 11.0 7.2 11.3 6.4 6.3 9.6 7.4 7.1 7.0 9.0 6.3 7.8 10.5 2.3 7.0 6.6 7.5 12.2 9.1 7.0 6.3 11.2 7.9 4.1 6.6 10.9 6.3 7.3 13.5 10.2 9.4 6.7 36.9 32.4 12.5 18.3 17.9 11.9 21.3 14.8 19.8 28.0 27.2 17.8 30.0 24.1 22.7 14.0 33.0 26.9 29.1 28.2 21.0 19.7 22.1 29.4 31.6 18.3 11.5 18.3 26.6 11.8 22.6 39.6 14.2 13.2 22.6 25.3 15.4 15.9 21.2 35.7 24.9 23.8 25.0 17.4 38.6 21.8 20.8 26.4 15.2 18.1 11.6 12.7 28.0 33.4 14.7 28.5 26.4 14.1 13.1 16.6 23.9 33.7 19.6 16.4 22.9 19.9 17.7 30.9 20.1 16.2 11.5 13.1 10.2 14.4 8.6 8.2 9.6 10.2 13.7 8.5 8.5 8.4 4.1 42.0 13.4 7.4 11.6 10.1 6.1 6.3 6.0 6.6 5.9 6.4 6.4 6.3 6.3 6.3 6.6 6.7 6.1 3.2 11.8 1.6 12.7 12.9 12.5 20.1 6.8 3.6 7.2 7.1 5.9 15.7 14.9 11.0 0.0 52.7 7.1 17.9 15.6 31.5 0.3 6.0 5.7 11.5 6.1 31.5 0.8 15.1 35.3 7.6 10.2 9.7 8.8 13.1 10.4 11.4 24.2 6.7 0.7 10.1 10.2 10.9 11.1 1.1 5.9 12.0 0.0 1.9 21.7 5.2 16.5 1.0 1.9 20.5 19.1 8.6 9.8 10.5 16.6 21.6 11.8 2.1 19.7 4.4 6.9 1.4 10.6 13.8 12.6 47.6 11.6 12.4 13.7 13.2 APLNR "AGTRL1, APJ, APJR, FLJ90771" ENSG00000134817 "Apelin receptor" P35414 11 57233577-57237235 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 268.8;lymphoid tissue: 101.0;placenta: 88.1" "Group enriched" "Detected in some" 7 "Adipocytes: 67.6;Endothelial cells: 98.5" "Cancer enhanced" "Detected in all" "glioma: 50.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "AF22: 4.9;HEL: 4.3;K-562: 1.3;NTERA-2: 1.8;SuSa: 2.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025842 Approved NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB025842: " "unprognostic (5.06e-2)" "unprognostic (3.56e-1)" "unprognostic (2.70e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-1)" "unprognostic (6.68e-3)" "unprognostic (1.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (4.72e-1)" "unprognostic (1.77e-3)" "unprognostic (3.27e-2)" "unprognostic (8.13e-2)" "unprognostic (1.13e-1)" "unprognostic (7.13e-3)" 17.3 3.7 47.1 9.4 46.3 0.1 10.6 52.0 45.7 2.3 22.7 5.4 4.5 3.5 0.3 4.1 1.2 13.0 23.7 48.3 130.5 5.7 18.5 8.1 9.6 268.8 97.4 0.7 2.0 2.9 2.4 88.1 92.2 1.0 6.0 0.0 3.5 1.9 15.2 7.1 4.2 9.9 99.9 101.0 3.2 1.4 92.7 4.1 9.5 10.8 4.2 6.2 1.7 122.4 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.1 46.3 52.0 45.7 48.3 130.5 268.8 97.4 92.2 99.9 92.7 122.4 67.6 0.0 0.0 6.5 0.6 2.3 0.1 0.0 0.0 0.0 0.5 0.6 3.2 1.5 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.3 0.3 98.5 0.0 0.0 0.0 0.2 0.1 2.6 0.0 0.5 0.0 0.0 10.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 2.6 0.2 0.0 0.5 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 2.7 0.0 0.0 0.3 3.1 0.1 0.2 2.7 0.0 0.1 APOBR "APOB100R, APOB48R" ENSG00000184730 "Apolipoprotein B receptor" Q0VD83 16 28494643-28498970 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 34.9;intestine: 26.3;lung: 11.6;lymphoid tissue: 36.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 149.9;granulocytes: 39.3;Intestinal goblet cells: 47.5;NK-cells: 65.9;Paneth cells: 84.8;Undifferentiated cells: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 41.6;HMC-1: 124.8;NB-4: 35.7;THP-1: 25.8;U-937: 30.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041667, HPA042093" Enhanced NA NA 700000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041667: AB_10793972, HPA042093: AB_10795393" "unprognostic (3.16e-1)" "unprognostic (8.01e-3)" "unprognostic (6.19e-3)" "prognostic favorable (3.26e-4)" "unprognostic (5.48e-2)" "unprognostic (4.79e-3)" "unprognostic (1.17e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-2)" "unprognostic (7.60e-3)" "unprognostic (7.96e-2)" "unprognostic (1.78e-1)" "unprognostic (1.34e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" "unprognostic (1.07e-1)" "unprognostic (1.25e-2)" 3.3 2.0 0.9 20.0 0.9 34.9 1.6 1.1 2.0 1.3 0.9 26.3 6.1 1.1 1.4 1.6 2.4 2.8 1.3 0.9 1.7 1.1 2.7 11.6 6.7 2.3 1.3 0.4 1.3 0.6 0.7 2.7 1.8 1.8 16.1 0.1 2.1 3.5 1.1 3.1 9.4 2.7 1.5 36.6 4.1 1.3 2.6 3.7 1.2 1.1 3.8 4.8 1.1 2.2 0.1 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.1 0.2 2.2 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 41.6 0.3 0.5 0.0 15.4 124.8 0.0 0.1 0.0 0.0 0.1 0.0 0.4 1.3 0.7 0.0 1.2 1.5 35.7 0.0 0.0 0.0 0.9 0.1 0.0 0.0 1.9 0.0 0.0 0.1 1.1 0.1 0.1 1.4 25.8 0.1 0.0 0.0 0.1 0.0 0.7 0.3 1.5 0.1 30.8 0.1 10.5 5.8 16.5 2.4 2.9 2.3 0.0 1.3 2.4 5.0 0.1 0.3 1.2 17.1 7.3 2.6 0.9 0.4 2.3 0.9 0.9 1.1 2.0 0.9 1.7 2.3 1.3 1.8 1.5 2.6 2.2 0.3 3.2 7.7 0.0 2.2 0.8 0.2 0.1 0.0 0.0 2.2 0.6 0.6 0.0 2.7 3.7 0.0 2.1 21.9 149.9 0.0 0.0 0.1 0.2 0.2 0.7 9.1 6.5 0.0 0.2 14.6 1.0 1.1 0.2 39.3 0.1 0.7 0.6 32.3 0.0 0.0 47.5 0.0 30.1 32.5 0.4 0.3 33.9 1.8 1.9 34.8 0.0 65.9 0.0 0.1 0.0 84.8 0.0 5.7 0.1 6.5 0.1 0.8 0.0 6.6 0.0 0.4 0.4 0.3 0.0 0.3 5.9 16.0 0.0 49.3 0.4 APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Approved Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA003187: AB_1079375" "unprognostic (2.53e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.86e-2)" "unprognostic (6.38e-3)" "unprognostic (3.45e-1)" "unprognostic (2.42e-1)" "unprognostic (6.18e-2)" "unprognostic (2.95e-1)" "unprognostic (6.45e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "prognostic favorable (2.56e-6)" "unprognostic (2.53e-2)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (5.88e-3)" 9.0 23.7 55.8 9.0 58.0 7.9 13.3 58.1 76.3 13.1 67.8 17.3 14.4 10.6 19.6 12.6 20.8 9.3 65.1 57.9 58.4 46.5 18.2 8.6 11.7 58.8 57.0 9.4 14.2 62.0 29.2 10.9 57.3 13.7 18.8 52.8 19.7 15.0 45.9 7.7 12.0 12.0 57.0 8.4 17.7 16.8 56.8 14.0 20.3 73.2 11.6 11.2 8.1 57.1 36.5 32.7 53.9 37.8 8.8 19.9 8.3 17.9 21.9 37.4 38.8 19.3 17.0 31.5 21.9 16.5 48.5 29.3 68.5 35.7 41.2 33.4 48.7 15.9 28.6 31.1 20.8 40.9 17.1 22.2 20.7 41.2 30.4 20.1 26.6 38.8 22.9 33.2 35.1 34.6 41.2 43.0 49.2 47.5 52.7 31.5 26.6 75.6 74.1 18.4 36.4 26.5 39.0 36.7 39.7 52.4 63.6 17.9 6.5 23.9 14.6 86.6 27.9 26.3 50.5 28.7 38.5 19.8 35.8 14.8 4.8 1.4 12.6 15.9 16.6 10.8 13.7 12.5 14.0 10.2 10.9 10.7 3.0 10.3 16.0 16.6 14.0 7.7 55.8 58.0 58.1 76.3 57.9 58.4 58.8 57.0 57.3 57.0 56.8 57.1 7.4 16.0 11.5 61.7 11.8 14.0 17.0 74.3 11.4 20.4 14.3 17.0 61.8 21.5 28.3 23.9 14.6 17.2 11.3 12.8 180.0 28.4 25.9 56.0 13.0 10.1 7.2 20.8 61.4 16.0 8.9 11.7 13.3 24.4 3.8 14.2 7.9 13.9 22.7 20.2 76.5 17.0 44.7 14.6 12.0 15.7 11.5 9.9 28.4 74.0 34.2 50.0 8.2 43.7 76.5 10.2 20.0 15.8 14.8 14.1 24.0 80.6 106.9 32.4 6.6 10.8 22.3 26.1 53.2 18.9 7.0 12.4 9.5 17.0 22.3 16.8 AQP4 MIWC ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 440.5;lung: 114.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1102.6;Alveolar cells type 2: 342.3;Astrocytes: 487.7;Muller glia cells: 227.2" "Cancer enriched" "Detected in some" 22 "glioma: 223.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.4;RPTEC TERT1: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions" "CAB005079: AB_2274338, CAB058689: AB_2665579, HPA014784: AB_1844967" "unprognostic (7.23e-5)" "unprognostic (1.55e-1)" "unprognostic (3.19e-8)" "unprognostic (3.68e-1)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.34e-1)" "unprognostic (5.38e-3)" "unprognostic (1.64e-3)" "unprognostic (8.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.10e-2)" 0.1 0.1 272.7 0.0 298.7 0.0 0.3 282.0 246.3 0.6 62.9 0.3 0.0 0.0 0.8 0.9 1.1 0.1 2.8 283.6 440.5 2.3 0.9 114.8 0.3 250.5 351.2 2.5 0.2 2.2 3.7 0.0 333.3 0.4 0.0 60.2 0.7 0.2 60.1 0.1 0.1 0.0 333.0 0.5 11.4 0.5 387.1 0.2 14.7 20.9 0.1 0.1 0.1 376.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.7 298.7 282.0 246.3 283.6 440.5 250.5 351.2 333.3 333.0 387.1 376.0 0.0 1102.6 342.3 487.7 0.0 0.0 0.8 0.6 0.0 3.1 0.8 0.9 13.9 4.3 76.6 3.7 6.2 0.0 0.0 0.1 3.9 0.3 0.0 0.7 0.1 1.8 0.0 0.0 3.0 0.0 0.0 0.8 0.0 0.0 3.8 0.0 0.0 0.5 0.0 1.7 1.1 0.0 0.0 0.0 0.3 0.0 5.0 0.8 0.0 9.4 0.0 227.2 0.0 12.1 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.1 9.1 0.0 4.3 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 2.0 ARAP2 "CENTD1, PARX" ENSG00000047365 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2" Q8WZ64 4 35948221-36244514 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.9;brain: 92.8" "Cell type enhanced" "Detected in many" "Astrocytes: 285.4;Late spermatids: 167.5;Oligodendrocytes: 781.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.7;hTCEpi: 12.7;MOLT-4: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035925 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Actin filaments" "HPA035925: AB_10672075" "unprognostic (2.97e-2)" "unprognostic (8.62e-2)" "unprognostic (3.43e-3)" "unprognostic (1.04e-1)" "unprognostic (8.86e-2)" "unprognostic (2.72e-3)" "unprognostic (1.09e-1)" "unprognostic (3.78e-3)" "unprognostic (2.04e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-3)" "unprognostic (2.96e-1)" "unprognostic (4.48e-2)" "unprognostic (4.54e-2)" "unprognostic (3.43e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-2)" 4.5 2.2 28.9 10.0 70.4 39.9 5.1 19.9 39.5 3.5 0.0 5.3 8.9 3.3 3.8 13.1 3.3 9.3 1.5 24.5 21.5 3.7 9.4 13.4 15.7 34.1 38.8 1.5 7.0 5.4 2.9 3.5 32.6 2.2 5.6 1.4 4.6 2.9 0.7 16.1 8.9 4.3 18.3 11.5 6.1 6.2 32.1 24.6 23.2 0.8 11.0 9.9 6.3 92.8 8.6 0.7 0.8 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 4.2 13.7 4.1 3.2 0.4 0.0 3.2 1.3 6.7 0.0 0.0 7.6 0.1 2.9 0.2 1.6 5.5 0.0 0.4 12.7 0.0 2.7 4.9 0.0 11.1 0.2 0.7 0.0 3.6 12.8 4.5 1.0 6.0 2.6 6.5 0.0 4.7 9.3 8.7 7.3 0.0 0.4 2.1 2.7 0.4 5.6 1.6 0.0 2.3 7.5 0.0 1.1 0.0 0.0 8.0 0.9 6.1 1.9 0.0 0.5 0.0 3.8 1.8 3.5 1.8 2.1 2.7 0.3 0.9 0.7 1.9 0.4 6.7 4.7 1.2 1.1 0.6 28.9 70.4 19.9 39.5 24.5 21.5 34.1 38.8 32.6 18.3 32.1 92.8 18.6 153.8 23.3 285.4 46.1 39.1 32.9 13.5 21.6 0.8 11.2 7.0 2.1 17.2 33.2 7.3 0.0 0.2 100.4 15.5 7.9 7.9 123.6 31.4 3.0 15.8 3.0 8.6 140.8 10.0 0.4 9.4 20.4 50.0 9.5 5.9 3.3 4.2 8.7 0.0 29.9 11.3 6.1 33.2 24.9 167.5 2.8 35.1 5.4 40.3 26.7 5.4 95.8 161.4 781.2 21.5 23.3 0.7 43.0 30.0 17.4 5.8 18.0 1.2 0.0 8.1 3.6 4.2 3.0 37.0 67.5 0.8 90.7 0.1 6.9 44.1 ARAP3 "CENTD3, DRAG1, FLJ21065" ENSG00000120318 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" Q8WWN8 5 141653401-141682230 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 33.2;Endothelial cells: 28.3;Hepatic stellate cells: 28.5;Horizontal cells: 38.7;Microglial cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.3;neutrophil: 2.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 39.4;HUVEC TERT2: 74.3;TIME: 53.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042887 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042887: AB_10796681" "unprognostic (1.98e-1)" "unprognostic (4.88e-2)" "unprognostic (9.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.58e-2)" "unprognostic (5.26e-2)" "unprognostic (3.77e-3)" "unprognostic (9.76e-2)" "unprognostic (3.43e-2)" "unprognostic (1.39e-1)" "unprognostic (4.42e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (4.96e-2)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" 11.4 4.1 4.6 5.4 4.7 6.2 10.1 5.2 5.4 9.5 1.5 4.5 3.2 7.5 5.4 3.2 7.8 6.7 14.1 3.3 2.9 7.8 2.1 15.8 2.3 4.1 4.4 3.7 2.5 5.3 5.1 11.9 4.4 7.4 2.6 3.9 3.9 5.8 7.0 2.6 4.6 5.9 3.1 7.3 4.3 1.6 6.3 0.7 8.5 9.2 1.2 7.8 7.3 2.9 11.9 7.5 29.4 0.0 1.8 4.5 0.3 7.0 7.9 7.2 9.2 4.7 0.9 0.1 39.4 2.6 11.7 12.8 5.0 16.8 5.5 0.2 2.1 11.0 12.6 0.1 8.2 0.9 0.4 8.3 7.6 3.9 8.9 20.1 74.3 0.0 0.8 0.1 1.0 0.3 0.0 9.5 17.4 3.9 9.4 0.2 2.3 0.0 0.8 5.4 0.5 24.7 15.1 0.8 12.7 10.6 0.4 2.8 53.3 4.8 10.8 1.3 14.7 0.0 0.1 0.1 12.4 12.6 24.3 0.3 0.5 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.1 0.2 4.6 4.7 5.2 5.4 3.3 2.9 4.1 4.4 4.4 3.1 6.3 2.9 33.2 3.2 8.6 0.3 0.3 0.5 1.7 3.1 0.0 6.1 0.9 2.2 5.2 0.0 2.6 1.8 0.0 0.1 1.6 1.3 0.0 1.2 0.0 0.7 2.3 28.3 0.0 0.0 2.4 0.7 0.1 2.2 1.1 1.2 1.3 0.0 28.5 0.3 1.3 38.7 3.2 1.3 2.0 4.4 2.1 0.6 0.3 2.2 0.0 15.0 2.7 3.6 2.1 1.5 0.1 4.6 1.8 1.5 1.6 2.8 0.0 0.1 0.9 0.9 0.0 1.2 3.3 0.5 0.9 0.8 0.4 0.1 1.5 0.4 2.7 3.6 ARF5 ENSG00000004059 "ADP ribosylation factor 5" P84085 7 127588386-127591700 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 3900000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (6.72e-3)" "unprognostic (2.34e-2)" "unprognostic (1.67e-2)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (5.81e-3)" "unprognostic (9.41e-2)" "unprognostic (2.69e-1)" "unprognostic (2.75e-2)" "unprognostic (7.02e-2)" "unprognostic (1.02e-1)" "unprognostic (9.69e-2)" "unprognostic (1.50e-1)" "unprognostic (1.26e-2)" "unprognostic (3.95e-1)" "unprognostic (2.46e-2)" 100.2 93.7 139.3 72.6 147.7 143.0 99.8 128.4 200.6 100.7 124.4 108.3 92.3 104.8 114.1 227.5 97.5 81.7 118.6 152.0 137.2 125.8 139.0 90.8 102.7 133.8 132.0 72.1 168.1 104.0 100.2 69.3 135.1 98.7 61.3 22.9 103.1 71.1 131.9 199.8 98.5 66.3 131.9 105.8 117.8 82.9 135.2 95.8 80.5 101.4 74.6 92.5 122.1 133.4 157.4 148.9 120.1 386.5 101.6 159.1 163.3 43.9 129.6 118.7 135.8 232.0 211.4 114.7 64.4 132.6 135.9 117.5 92.4 198.0 38.4 104.9 222.8 44.9 137.5 160.2 150.1 69.7 100.1 163.1 196.2 77.7 75.8 94.5 173.2 164.1 105.1 124.1 116.9 531.2 249.0 303.7 179.9 157.1 191.7 148.3 73.9 245.6 198.2 158.7 349.1 226.2 142.8 461.8 116.1 77.6 123.9 108.0 103.7 177.3 75.3 128.0 101.9 115.2 77.5 153.9 181.1 142.0 154.6 289.0 321.4 279.7 144.3 270.3 146.7 129.5 151.1 148.4 409.6 117.2 112.0 122.2 447.5 156.5 216.2 259.6 181.8 381.8 139.3 147.7 128.4 200.6 152.0 137.2 133.8 132.0 135.1 131.9 135.2 133.4 110.3 3.2 12.1 28.4 81.3 105.7 72.9 217.1 130.9 14.8 111.8 180.7 2.0 91.5 83.0 112.2 0.0 151.6 89.7 89.4 201.5 107.8 39.3 90.3 95.7 73.9 119.9 102.2 46.5 90.7 125.0 82.2 135.5 88.2 21.0 91.1 75.7 51.6 102.7 20.2 42.5 108.8 140.4 129.6 221.9 40.7 93.2 123.9 149.4 28.1 118.6 27.6 82.4 27.2 36.2 86.4 134.0 94.8 75.1 57.2 147.5 160.0 58.4 11.9 72.3 58.7 85.4 99.2 116.7 248.3 153.4 146.3 100.2 69.1 125.4 93.4 ARFGAP2 "FLJ14576, IRZ, Zfp289, ZNF289" ENSG00000149182 "ADP ribosylation factor GTPase activating protein 2" Q8N6H7 11 47164299-47177125 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016649, HPA018152" Enhanced Supported "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "HPA016649: AB_1844980, HPA018152: AB_1844979" "unprognostic (1.69e-2)" "unprognostic (9.11e-2)" "unprognostic (5.91e-2)" "unprognostic (3.75e-2)" "unprognostic (2.20e-2)" "unprognostic (1.12e-1)" "unprognostic (4.81e-3)" "unprognostic (1.23e-1)" "unprognostic (1.25e-1)" "unprognostic (2.41e-1)" "unprognostic (3.42e-2)" "unprognostic (7.00e-2)" "prognostic favorable (7.65e-7)" "unprognostic (2.05e-1)" "unprognostic (9.36e-2)" "unprognostic (1.06e-1)" "unprognostic (9.20e-2)" 38.0 51.4 62.1 36.3 63.9 82.2 41.7 63.2 68.3 42.3 57.2 49.4 40.0 43.3 35.5 60.8 49.3 32.1 58.7 62.5 60.1 47.6 76.8 40.7 51.9 65.1 61.8 44.6 69.7 48.2 38.7 39.9 61.8 51.4 39.4 38.9 56.1 41.7 115.9 78.7 43.8 38.8 60.6 51.2 55.7 30.7 63.1 49.8 47.4 81.4 50.5 44.7 43.3 70.3 55.7 36.4 54.9 43.3 45.9 37.3 51.6 51.2 48.1 64.1 48.4 41.3 45.3 91.3 32.4 58.7 40.8 82.3 47.2 74.6 40.3 45.0 46.1 77.6 85.5 50.8 53.7 107.0 84.4 56.7 82.3 33.3 71.1 46.1 60.4 65.6 111.8 67.8 58.5 102.5 50.8 87.8 43.6 98.3 48.4 78.8 94.8 116.8 60.3 79.3 53.0 47.0 58.7 81.7 38.8 26.1 126.8 78.8 48.7 55.2 43.3 50.5 68.6 58.6 60.7 78.3 38.6 81.2 56.4 108.5 69.1 92.8 74.0 77.3 66.6 59.0 57.1 66.2 65.9 63.1 63.0 63.4 41.8 69.2 98.4 35.4 71.8 108.1 62.1 63.9 63.2 68.3 62.5 60.1 65.1 61.8 61.8 60.6 63.1 70.3 23.8 35.3 45.9 25.1 46.5 22.2 31.4 22.1 29.6 73.6 30.9 25.8 13.0 20.0 41.2 31.3 114.7 64.3 40.7 38.6 25.4 38.7 2.7 20.3 26.4 29.8 45.4 47.1 16.2 36.6 47.1 29.7 34.1 27.0 60.8 44.9 31.1 44.0 36.8 74.0 15.1 35.0 38.7 33.6 25.4 6.6 34.2 28.6 28.4 15.9 58.1 51.1 71.1 13.0 23.7 39.2 45.0 26.4 31.7 26.4 41.0 26.3 34.1 115.4 39.5 33.0 28.0 24.7 35.9 30.3 26.7 91.8 43.7 40.3 36.3 34.0 ARFGEF3 "BIG3, C6orf92, dJ171N11.1, KIAA1244, PPP1R33" ENSG00000112379 "ARFGEF family member 3" Q5TH69 6 138161939-138344663 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.4;salivary gland: 18.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 114.6;Excitatory neurons: 200.9;Inhibitory neurons: 207.8;Oligodendrocyte precursor cells: 173.9;Oligodendrocytes: 378.1" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 14.8;RH-30: 13.4;RT4: 19.4;SK-BR-3: 22.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036350 Uncertain NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA036350: AB_10672084" "prognostic unfavorable (8.20e-4)" "unprognostic (4.31e-2)" "unprognostic (9.91e-3)" "unprognostic (5.91e-2)" "unprognostic (2.20e-2)" "unprognostic (4.53e-2)" "unprognostic (4.30e-3)" "unprognostic (1.21e-2)" "unprognostic (7.41e-2)" "unprognostic (7.82e-2)" "unprognostic (3.46e-2)" "unprognostic (4.93e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-1)" "unprognostic (2.38e-1)" "unprognostic (8.87e-2)" "unprognostic (1.69e-2)" 1.2 3.8 13.4 0.7 16.4 0.4 7.9 20.1 17.7 5.0 0.0 4.2 2.2 0.7 0.9 0.4 2.2 1.7 1.0 16.7 13.0 2.1 0.1 6.4 0.2 11.1 17.7 0.1 8.7 15.8 7.0 1.4 14.4 12.0 4.8 2.8 18.0 1.0 0.2 1.2 1.9 0.7 7.5 0.4 10.0 0.6 15.2 0.1 1.9 0.7 0.2 3.4 0.4 28.4 8.0 3.1 0.0 0.6 0.0 0.0 4.7 0.3 0.2 0.2 0.0 0.1 0.4 0.0 3.1 0.3 2.7 2.6 3.8 2.0 0.0 0.0 4.9 0.0 1.5 0.9 0.0 3.0 0.0 0.0 0.9 0.0 0.9 3.5 4.1 2.7 0.0 4.9 0.0 14.8 0.0 0.0 2.7 8.5 3.4 0.6 13.4 2.6 2.6 19.4 6.9 0.0 7.8 22.2 0.9 0.3 4.4 0.0 0.4 0.2 2.2 0.0 7.9 1.7 6.7 0.0 3.2 1.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.4 20.1 17.7 16.7 13.0 11.1 17.7 14.4 7.5 15.2 28.4 9.4 16.0 114.6 34.3 0.5 0.0 18.8 0.0 6.2 19.0 39.9 12.6 6.4 14.3 44.6 3.7 0.0 16.5 0.8 2.5 3.9 11.4 83.0 8.6 1.4 11.9 66.7 2.7 200.9 24.7 2.4 4.1 41.3 17.7 2.5 0.1 8.2 0.3 1.4 11.8 207.8 44.2 0.0 0.0 0.0 22.0 0.0 0.5 0.0 36.5 2.0 0.9 0.0 173.9 378.1 14.2 8.4 0.0 0.9 67.6 2.5 0.3 37.2 3.3 0.0 3.5 0.9 4.1 1.1 3.0 0.0 6.2 0.8 0.1 13.2 42.7 ARHGAP23 KIAA1501 ENSG00000275832 "Rho GTPase activating protein 23" Q9P227 17 38419280-38512385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 97.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.4;Hepatic stellate cells: 46.1;Oligodendrocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 296.7;RT4: 115.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019818, HPA047291" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" Cytosol "HPA019818: AB_1844993, HPA047291: AB_2680012" "unprognostic (3.35e-1)" "unprognostic (5.11e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (6.87e-5)" "unprognostic (9.53e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (1.99e-1)" "unprognostic (5.56e-2)" "unprognostic (1.50e-3)" "prognostic unfavorable (3.24e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.38e-5)" "unprognostic (8.36e-2)" "unprognostic (5.83e-2)" "unprognostic (4.57e-2)" "unprognostic (2.25e-1)" 25.6 13.8 36.2 8.3 66.2 10.7 18.8 47.2 54.6 25.9 5.5 22.8 3.0 28.4 3.7 60.8 18.4 7.8 27.3 34.4 37.5 11.8 2.9 28.0 4.1 63.7 59.6 18.1 3.5 3.1 6.2 19.4 54.1 19.9 2.8 8.5 12.8 12.5 10.6 61.1 10.4 11.6 43.0 30.7 13.4 16.1 66.1 5.4 9.5 5.8 11.0 36.3 29.5 97.8 32.5 17.2 15.2 5.1 9.5 31.1 19.6 44.8 49.5 37.7 21.8 56.8 55.1 0.7 35.2 102.5 18.7 296.7 1.7 62.3 26.6 3.5 3.3 0.0 55.1 0.4 47.2 3.0 0.3 18.8 11.8 27.7 17.3 31.0 39.4 6.0 0.6 8.3 21.6 0.0 10.2 6.3 9.0 1.2 6.3 17.0 33.0 10.4 16.0 115.7 3.7 8.8 26.9 0.1 0.3 21.2 6.7 7.9 57.7 62.6 22.9 12.9 12.1 6.5 7.3 1.9 16.3 8.1 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 66.2 47.2 54.6 34.4 37.5 63.7 59.6 54.1 43.0 66.1 97.8 27.2 12.8 1.5 23.8 0.7 9.9 17.5 10.6 9.1 59.4 1.7 3.9 20.4 1.5 13.2 3.7 0.0 27.0 0.2 0.1 0.0 2.9 7.6 8.5 10.0 34.9 0.0 4.0 9.3 1.4 3.1 11.6 3.1 5.7 0.0 4.9 46.1 0.5 5.1 26.9 16.2 0.4 2.0 2.5 4.2 21.0 9.0 1.2 1.8 9.4 0.2 9.6 0.0 20.1 129.2 7.0 0.1 7.2 1.7 15.4 0.0 0.2 8.3 3.4 0.0 10.9 7.6 13.5 2.7 27.5 25.9 16.6 1.8 1.3 0.3 42.2 ARHGAP28 "FLJ10312, KIAA1314" ENSG00000088756 "Rho GTPase activating protein 28" Q9P2N2 18 6729716-6915716 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "placenta: 25.9;testis: 77.5" "Group enriched" "Detected in many" 14 "Early spermatids: 536.8;Late spermatids: 488.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "neutrophil: 3.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 3.0" "Cell line enhanced" "Detected in many" "AF22: 30.4;CACO-2: 32.8;SuSa: 22.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030413, HPA030414, HPA030415" Enhanced Supported "Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" "HPA030413: AB_10601455, HPA030414: AB_10670042, HPA030415: AB_10669598" "unprognostic (8.33e-2)" "unprognostic (8.79e-3)" "unprognostic (3.15e-3)" "unprognostic (6.94e-5)" "unprognostic (1.49e-1)" "unprognostic (2.92e-2)" "unprognostic (1.11e-3)" "unprognostic (1.10e-1)" "unprognostic (7.56e-3)" "unprognostic (9.52e-4)" "unprognostic (1.43e-2)" "unprognostic (3.12e-1)" "unprognostic (4.53e-3)" "unprognostic (3.59e-3)" "unprognostic (6.00e-2)" "unprognostic (3.61e-2)" "unprognostic (2.76e-2)" 4.7 1.9 1.1 1.7 1.2 0.8 2.7 1.7 1.6 8.6 0.8 1.9 1.7 2.9 8.7 1.9 3.1 6.6 2.0 1.5 1.6 8.4 0.9 4.6 1.7 0.4 0.2 10.4 3.8 3.0 0.8 25.9 0.5 3.9 2.3 1.4 0.8 2.2 4.9 2.1 1.8 1.4 0.1 12.6 2.1 77.5 1.1 3.8 2.9 1.6 0.9 5.4 3.0 0.8 0.2 0.2 30.4 3.1 6.3 10.5 4.9 2.2 5.1 2.5 5.3 32.8 0.2 0.2 1.0 0.4 1.7 1.4 0.1 0.8 3.7 1.0 1.8 0.1 2.9 0.2 1.1 0.1 0.1 12.6 0.6 2.7 0.2 0.3 7.8 0.5 0.8 2.5 4.1 0.5 0.5 0.3 9.6 0.4 1.4 0.1 2.7 0.2 0.0 2.9 2.9 11.9 0.1 2.8 0.5 22.6 0.2 0.1 1.3 0.5 13.1 10.1 0.4 0.2 0.1 0.1 5.0 0.3 1.1 0.7 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 3.0 0.1 0.0 0.2 0.0 0.0 1.1 1.2 1.7 1.6 1.5 1.6 0.4 0.2 0.5 0.1 1.1 0.8 8.3 0.0 1.9 6.2 0.1 1.9 1.3 0.2 0.0 1.5 0.9 0.5 1.8 0.0 0.7 1.8 20.9 14.9 0.0 0.0 0.0 1.1 536.8 0.5 14.6 7.9 0.0 0.0 7.1 2.7 2.7 16.1 0.0 0.4 0.0 25.8 4.2 0.2 2.1 0.0 34.4 0.1 0.0 0.3 0.4 488.0 18.3 0.5 0.0 12.2 0.0 0.2 0.0 24.6 3.6 0.7 0.0 14.3 0.1 4.7 0.0 3.8 0.0 0.8 0.0 11.0 5.4 14.3 3.7 0.8 1.4 6.6 0.3 23.7 0.0 1.3 ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 68.3;intestine: 53.2;lung: 39.5;lymphoid tissue: 106.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Cytotrophoblasts: 40.1;dendritic cells: 62.7;Extravillous trophoblasts: 56.6;Hofbauer cells: 40.0;monocytes: 72.4;Syncytiotrophoblasts: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.7;Karpas-707: 100.4;RPMI-8226: 74.7;THP-1: 92.3;U-266/70: 130.8;U-937: 72.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA019816: AB_1853923, HPA079252: " "unprognostic (1.34e-1)" "unprognostic (5.13e-3)" "unprognostic (5.17e-3)" "prognostic favorable (6.02e-4)" "unprognostic (2.26e-1)" "prognostic favorable (7.82e-4)" "unprognostic (1.59e-2)" "unprognostic (2.17e-2)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (5.33e-2)" 11.2 5.5 3.6 43.1 3.4 68.3 5.5 4.4 7.5 4.2 5.1 12.4 7.2 3.5 0.5 5.5 6.7 5.0 4.4 3.3 4.4 7.8 7.4 39.5 58.4 9.1 5.4 2.0 2.7 0.8 4.5 6.0 6.9 5.9 2.6 8.7 6.4 1.5 2.1 3.9 53.2 2.2 7.6 106.1 10.9 3.5 8.1 32.9 9.0 0.8 18.6 6.6 5.5 11.4 11.2 2.1 0.1 12.1 0.0 0.0 27.8 0.1 0.0 0.0 0.0 29.2 13.9 73.7 3.0 0.0 0.4 9.6 2.1 0.6 0.0 54.7 1.0 10.1 22.6 3.5 0.4 48.6 56.2 0.0 2.9 0.1 0.0 0.0 0.1 46.8 6.8 100.4 0.0 0.6 54.5 43.4 7.6 1.9 5.4 52.0 0.3 74.7 0.0 0.2 0.6 0.2 16.8 0.0 4.5 0.7 3.5 92.3 4.8 0.2 1.9 0.2 0.3 130.8 60.2 58.8 0.3 72.1 5.4 6.7 24.4 25.3 45.7 21.2 38.8 15.9 52.2 54.1 22.5 18.3 68.9 53.6 37.0 28.0 20.9 13.3 43.5 59.8 3.6 3.4 4.4 7.5 3.3 4.4 9.1 5.4 6.9 7.6 8.1 11.4 2.0 48.1 8.4 0.0 17.8 0.0 0.0 0.0 0.0 0.0 15.2 11.0 0.0 0.0 1.8 11.0 0.0 40.1 62.7 0.0 0.0 2.6 0.0 4.5 0.7 1.6 0.0 0.0 0.0 3.8 56.6 1.3 0.0 3.5 3.8 0.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 72.4 0.0 0.0 0.0 0.0 7.8 0.0 0.0 15.2 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 75.5 30.2 0.1 0.0 0.0 ARHGEF2 "GEF-H1, GEFH1, KIAA0651, Lfc, LFP40, P40" ENSG00000116584 "Rho/Rac guanine nucleotide exchange factor 2" Q92974 1 155946851-156007070 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Mitosis, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043437 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 3: Monocytes - Immune response regulation" "HPA043437: AB_2678481" "unprognostic (2.27e-2)" "unprognostic (8.30e-3)" "unprognostic (3.24e-3)" "unprognostic (1.90e-3)" "unprognostic (4.14e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (9.20e-6)" "unprognostic (5.96e-2)" "unprognostic (2.14e-1)" "unprognostic (3.62e-2)" "unprognostic (2.59e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (7.17e-6)" "unprognostic (4.63e-2)" "unprognostic (2.70e-1)" "unprognostic (8.85e-3)" "unprognostic (7.98e-2)" 48.9 12.3 52.6 39.2 80.8 64.0 40.8 69.0 77.8 38.8 18.7 47.3 18.8 37.0 15.2 25.8 42.1 31.1 42.8 55.5 56.2 35.7 13.2 89.9 48.4 85.9 75.9 28.1 15.1 18.5 16.8 32.1 84.1 27.3 28.8 11.1 25.0 15.1 17.8 17.9 45.4 29.9 60.9 69.9 39.9 33.9 77.2 38.6 46.7 16.8 32.6 37.8 31.4 130.6 32.0 25.7 44.0 30.3 41.4 51.9 45.3 69.9 89.4 67.2 71.5 23.3 23.6 79.4 41.9 53.8 35.4 45.7 26.7 22.2 50.9 32.5 22.9 105.1 40.9 14.0 162.4 138.6 87.8 61.1 90.4 100.2 122.1 50.7 55.7 60.5 59.2 94.2 96.2 17.7 70.2 187.2 48.8 53.4 17.0 75.5 61.3 135.9 28.3 19.0 72.1 33.1 30.1 43.6 246.1 43.6 45.0 188.7 73.6 57.7 32.7 50.9 89.8 155.7 171.1 55.6 82.4 68.7 144.6 15.1 20.6 17.1 15.7 18.1 10.8 14.6 9.9 11.3 18.2 13.1 9.6 11.0 31.7 11.0 21.9 8.7 9.9 28.2 52.6 80.8 69.0 77.8 55.5 56.2 85.9 75.9 84.1 60.9 77.2 130.6 26.4 38.5 73.4 2.9 43.9 15.2 28.1 12.6 10.8 54.1 15.7 12.3 6.2 10.0 12.0 16.5 2.1 3.5 32.1 21.1 7.9 15.5 52.9 6.6 10.2 32.3 30.5 48.6 30.8 5.3 22.8 24.8 59.1 13.3 27.9 8.9 23.2 1.0 29.7 1.7 17.0 20.9 16.2 49.0 67.8 16.1 11.5 46.0 24.9 20.6 82.9 12.9 48.4 22.1 105.5 16.5 22.5 10.1 20.0 16.7 9.8 2.2 13.0 3.3 59.2 32.9 30.8 3.1 4.1 11.7 13.8 3.4 29.7 2.1 14.2 40.2 ARID1B "6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R" ENSG00000049618 "AT-rich interaction domain 1B" Q8NFD5 6 156776020-157210779 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 404.3;Inhibitory neurons: 475.4;Microglial cells: 327.0;Oligodendrocyte precursor cells: 417.7;Oligodendrocytes: 503.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016511, HPA075291" Approved Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA016511: AB_1845008, HPA075291: AB_2686743" "prognostic unfavorable (1.04e-4)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (5.42e-2)" "unprognostic (7.47e-2)" "unprognostic (1.40e-2)" "unprognostic (2.73e-2)" "unprognostic (2.89e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.16e-4)" "unprognostic (2.53e-1)" "unprognostic (5.33e-2)" "unprognostic (1.07e-3)" "unprognostic (2.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-1)" 15.2 12.0 14.6 14.5 13.4 28.7 15.6 29.0 16.0 19.0 2.2 15.9 14.2 17.0 11.3 15.7 18.6 14.4 14.4 20.4 10.1 13.2 9.7 14.6 18.2 13.4 10.9 27.5 17.1 28.2 12.2 11.7 11.1 14.6 12.1 11.7 20.4 12.7 33.6 23.2 15.3 15.8 7.3 18.4 12.5 9.8 12.5 25.4 22.0 25.4 18.8 17.4 17.4 17.2 13.0 19.4 29.6 41.2 24.7 21.5 20.4 14.6 18.6 18.1 18.0 17.7 20.0 43.0 8.1 23.9 22.4 16.5 25.2 23.3 18.1 40.4 18.1 30.6 19.6 22.1 17.1 25.3 21.8 25.5 18.4 27.1 24.6 20.4 25.6 26.8 35.8 32.3 13.2 15.9 29.1 30.5 15.3 18.3 10.5 66.3 12.7 22.9 12.7 24.3 28.0 34.7 28.3 29.4 15.8 15.7 19.6 40.2 26.4 23.4 23.6 22.0 27.5 21.8 18.2 52.7 19.7 30.3 32.0 5.0 2.3 2.3 4.1 1.9 3.7 5.3 3.5 2.8 1.8 6.9 2.9 4.1 4.2 2.4 2.1 9.4 3.7 1.2 14.6 13.4 29.0 16.0 20.4 10.1 13.4 10.9 11.1 7.3 12.5 17.2 85.7 48.1 51.8 282.7 83.3 47.5 22.3 22.3 41.5 36.0 70.9 44.4 36.9 27.1 32.6 126.9 29.2 14.7 103.7 21.8 7.9 40.8 15.0 70.8 124.5 43.9 40.8 37.8 404.3 34.5 7.5 49.9 31.1 78.0 38.7 137.1 33.9 27.3 14.1 47.1 475.4 33.7 20.3 32.6 36.1 19.4 56.8 49.1 30.2 327.0 59.4 21.9 24.7 417.7 503.7 46.6 26.9 62.8 70.2 28.1 26.8 18.4 29.5 29.6 46.0 43.1 56.7 8.0 12.2 39.7 55.7 17.5 51.9 72.9 36.3 27.1 ARL15 "ARFRP2, FLJ20051" ENSG00000185305 "ADP ribosylation factor like GTPase 15" Q9NXU5 5 53883942-54310582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 441.6;Inhibitory neurons: 285.2;Microglial cells: 408.5;Oligodendrocyte precursor cells: 184.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044604, HPA063820" Uncertain Approved "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Plasma membrane, Cell Junctions" "HPA044604: AB_10960542, HPA063820: AB_2685131" "unprognostic (2.18e-1)" "unprognostic (4.32e-2)" "unprognostic (1.82e-2)" "unprognostic (2.41e-2)" "unprognostic (1.08e-1)" "unprognostic (3.70e-1)" "unprognostic (8.52e-3)" "unprognostic (1.16e-2)" "unprognostic (3.05e-2)" "unprognostic (6.56e-2)" "unprognostic (4.26e-3)" "unprognostic (3.86e-1)" "unprognostic (2.48e-3)" "unprognostic (1.35e-1)" "unprognostic (9.15e-2)" "unprognostic (5.60e-2)" "unprognostic (1.08e-1)" 14.0 12.5 6.6 5.6 7.5 1.9 13.0 5.6 10.0 17.7 7.2 10.6 11.9 16.0 7.6 9.8 8.2 14.5 14.0 8.5 7.1 17.9 9.8 7.6 6.3 5.8 6.2 5.7 5.0 3.2 8.5 22.3 6.0 10.0 10.9 7.6 10.5 6.8 3.3 11.3 9.9 16.6 6.1 8.2 8.3 9.3 6.8 10.6 8.4 11.7 8.0 13.6 8.8 6.2 3.2 5.5 8.5 15.6 7.0 7.8 11.8 10.2 15.1 9.4 20.7 21.1 8.0 32.0 14.9 9.1 11.0 7.7 13.2 14.1 12.4 3.2 13.9 36.9 7.1 2.8 2.5 4.5 43.8 10.0 10.1 15.8 9.5 14.2 20.8 7.0 32.4 5.3 6.5 7.7 7.5 4.3 3.0 1.6 3.9 6.2 10.4 0.8 12.8 30.3 11.3 7.1 13.1 6.7 7.9 15.6 8.6 4.7 11.4 5.7 9.6 5.4 6.7 1.8 1.7 34.8 9.9 10.6 9.5 1.1 1.8 2.2 1.3 1.4 0.7 1.0 0.9 0.9 2.4 0.7 0.9 0.7 3.5 0.7 1.2 0.3 2.3 1.2 6.6 7.5 5.6 10.0 8.5 7.1 5.8 6.2 6.0 6.1 6.8 6.2 44.5 3.2 7.7 33.6 6.5 9.7 7.9 5.8 8.0 5.1 4.8 5.8 7.5 5.7 4.5 12.9 14.6 52.5 5.2 7.5 21.5 3.2 3.4 4.1 6.9 35.1 20.9 8.6 441.6 4.9 4.9 8.5 6.6 5.1 2.5 3.2 26.0 4.9 8.4 1.7 285.2 7.6 18.3 8.7 8.7 1.5 4.4 12.5 1.8 408.5 5.0 3.2 6.2 184.5 104.7 6.9 7.6 3.8 4.7 5.4 5.7 10.0 3.9 3.0 6.6 3.6 5.3 1.0 3.5 5.9 10.1 42.7 8.9 24.4 7.1 8.4 ARL4A ARL4 ENSG00000122644 "ADP ribosylation factor like GTPase 4A" P40617 7 12686856-12690958 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 191.1" "Group enriched" "Detected in all" 4 "Early spermatids: 1523.0;Late spermatids: 3892.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 261.3;K-562: 328.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064513 Supported Nucleoplasm,Cytosol NA Yes "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA064513: AB_2685276" "unprognostic (8.29e-2)" "unprognostic (1.34e-1)" "unprognostic (3.94e-1)" "unprognostic (4.97e-2)" "unprognostic (3.88e-2)" "unprognostic (7.43e-2)" "unprognostic (1.34e-2)" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.23e-1)" "unprognostic (3.02e-2)" "unprognostic (3.57e-2)" "unprognostic (7.27e-3)" "unprognostic (1.74e-1)" "unprognostic (9.29e-2)" "unprognostic (9.42e-3)" "unprognostic (9.49e-3)" 31.6 7.9 17.1 16.8 20.1 98.4 55.3 14.3 25.8 38.0 22.5 40.7 29.9 16.8 13.8 60.0 27.7 19.2 15.5 23.0 15.4 8.9 15.6 19.4 18.6 14.4 14.3 8.0 7.2 5.3 9.2 23.6 14.5 21.0 34.7 6.7 86.6 16.5 9.1 88.5 62.7 25.1 14.7 21.0 24.5 191.1 15.4 22.7 19.2 8.7 15.9 21.4 63.8 18.6 45.0 46.7 121.5 261.3 19.3 31.8 0.3 17.9 16.2 28.7 17.2 41.6 32.9 0.3 7.5 25.4 73.4 12.6 27.3 22.6 28.9 9.8 20.4 9.2 61.7 39.3 39.8 39.6 16.0 14.3 88.3 16.7 74.2 18.1 69.0 17.7 328.1 42.5 29.4 19.3 2.2 55.6 44.2 129.2 53.1 0.0 42.4 20.8 37.8 21.3 22.3 20.8 29.5 31.1 6.3 31.3 15.3 32.0 24.3 11.5 40.6 43.5 73.1 19.4 27.2 10.3 29.7 16.5 46.4 8.1 14.8 0.7 11.3 25.7 31.7 41.0 26.8 17.7 14.4 44.7 12.9 10.8 2.2 13.0 32.1 12.8 17.8 13.6 17.1 20.1 14.3 25.8 23.0 15.4 14.4 14.3 14.5 14.7 15.4 18.6 134.0 22.4 20.3 1.0 96.9 339.7 179.1 144.5 70.0 20.9 217.9 230.0 15.8 64.3 86.6 20.2 85.5 152.9 61.0 236.6 27.4 47.8 1523.0 179.1 41.5 162.5 62.6 249.9 11.6 29.6 18.7 46.1 63.2 86.5 80.5 27.7 157.1 21.7 59.5 3.3 3.4 107.1 337.7 168.2 171.1 3892.8 69.0 170.9 120.9 17.8 38.7 11.0 3.1 36.7 8.7 55.3 118.0 26.7 24.4 53.4 641.5 14.6 102.5 125.9 13.1 59.5 55.3 564.1 57.5 134.9 234.7 444.0 98.0 32.4 124.2 89.1 ARMCX2 "ALEX2, GASP9, KIAA0512" ENSG00000184867 "Armadillo repeat containing X-linked 2" Q7L311 X 101655281-101659850 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 154.8" "Cell type enhanced" "Detected in many" "Sertoli cells: 59.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 164.1;NTERA-2: 117.2;SuSa: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005761 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA005761: AB_10600782" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (4.25e-2)" "unprognostic (1.48e-1)" "unprognostic (9.59e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (3.41e-2)" "prognostic favorable (3.45e-5)" "unprognostic (9.06e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.12e-1)" "unprognostic (6.73e-2)" "unprognostic (1.25e-1)" 17.0 46.2 28.7 11.5 29.1 0.5 17.6 22.8 29.7 36.9 26.5 25.4 5.4 30.6 154.8 9.2 28.8 20.6 33.2 29.1 31.6 28.3 3.2 16.8 8.5 25.9 26.2 47.8 18.9 71.2 78.3 26.3 27.5 28.3 7.9 15.3 44.5 67.9 6.2 6.5 13.0 32.3 23.4 21.3 16.3 5.8 28.1 7.7 59.7 7.5 6.5 26.9 20.1 25.4 0.0 0.0 50.8 0.4 43.6 39.4 0.4 56.0 70.4 1.4 1.4 0.0 21.8 0.0 0.0 74.6 0.0 1.5 0.0 1.3 0.6 0.0 2.0 0.2 60.9 0.0 46.4 0.4 0.1 63.7 17.6 43.5 0.4 68.3 59.7 0.0 0.2 0.3 164.1 0.0 0.0 0.6 117.2 3.4 0.3 14.5 88.9 0.3 2.8 0.0 20.4 36.6 0.0 0.2 1.7 90.3 25.9 0.1 13.0 61.9 65.1 38.8 0.4 0.0 0.0 0.2 55.7 0.1 1.2 0.0 0.4 0.0 1.0 0.9 0.4 2.8 0.9 0.9 0.7 4.0 2.4 2.5 0.0 2.8 0.6 0.9 0.7 1.1 28.7 29.1 22.8 29.7 29.1 31.6 25.9 26.2 27.5 23.4 28.1 25.4 10.4 16.0 6.4 8.5 8.2 4.2 16.4 5.8 21.1 12.5 18.0 20.8 28.7 5.7 11.4 33.1 8.4 1.2 2.4 0.1 3.9 9.6 0.2 11.2 23.4 13.3 9.1 3.2 15.4 2.0 0.7 28.4 4.6 15.2 2.5 18.1 19.2 0.7 3.8 1.7 14.3 3.0 2.0 2.4 6.5 1.3 24.2 7.4 5.4 11.2 7.1 9.3 0.0 16.1 14.0 2.2 0.1 24.5 2.8 16.5 0.3 4.3 4.9 11.3 59.2 31.8 23.9 1.4 1.9 3.8 3.0 5.1 2.5 4.6 1.6 7.2 ARMCX3 "ALEX3, GASP6" ENSG00000102401 "Armadillo repeat containing X-linked 3" Q9UH62 X 101622797-101627843 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 88.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000325, HPA000967, HPA001530" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA000325: AB_1078206, HPA000967: AB_1078208, HPA001530: AB_2666349" "unprognostic (1.67e-1)" "unprognostic (2.14e-1)" "unprognostic (5.23e-2)" "unprognostic (8.69e-3)" "unprognostic (1.73e-2)" "unprognostic (1.47e-2)" "unprognostic (9.72e-3)" "unprognostic (2.19e-2)" "unprognostic (4.77e-2)" "unprognostic (6.80e-2)" "unprognostic (3.38e-3)" "unprognostic (2.12e-2)" "prognostic favorable (1.55e-5)" "unprognostic (3.29e-2)" "unprognostic (3.13e-1)" "unprognostic (1.07e-2)" "unprognostic (1.55e-2)" 34.9 58.9 30.8 24.4 33.0 14.7 32.2 35.4 35.7 45.0 27.6 31.5 20.2 40.9 105.3 18.1 27.7 34.0 51.0 34.1 38.7 37.2 24.6 29.5 21.8 34.5 33.7 38.3 57.4 103.6 47.7 45.4 34.8 44.5 21.8 19.0 59.6 46.7 30.7 11.9 21.5 36.3 35.4 41.3 29.7 12.9 35.5 20.1 49.9 63.6 21.5 31.9 22.5 37.7 26.4 18.8 48.8 23.9 109.4 118.3 10.0 56.5 54.3 23.2 68.3 20.7 21.5 9.5 31.7 64.7 50.8 5.0 34.9 20.2 28.7 21.6 23.2 18.7 64.9 30.2 85.2 18.2 41.5 67.0 27.4 30.9 30.3 65.1 47.6 11.6 15.2 78.9 67.4 10.9 15.0 0.8 24.4 49.5 4.3 19.1 62.2 8.9 36.0 10.1 22.1 18.9 28.3 1.5 63.9 67.7 19.2 19.0 67.5 29.8 18.9 70.8 11.2 69.7 20.9 0.1 50.4 14.5 25.5 43.6 15.3 13.6 14.6 15.8 18.3 15.0 14.0 12.4 15.8 9.8 15.2 10.6 5.6 13.7 16.8 25.8 9.0 14.4 30.8 33.0 35.4 35.7 34.1 38.7 34.5 33.7 34.8 35.4 35.5 37.7 67.4 44.8 36.1 16.3 61.1 37.9 81.2 40.6 42.7 63.1 70.9 42.3 114.6 50.1 48.4 75.4 58.4 55.3 61.1 20.4 37.2 53.9 0.6 42.2 80.9 69.2 82.4 25.6 35.9 30.6 27.4 85.8 33.1 78.8 79.1 45.5 58.2 48.6 50.7 62.2 41.8 67.6 40.7 52.5 84.9 2.8 64.7 72.3 97.8 18.7 27.2 86.6 34.0 28.6 31.0 30.6 22.1 72.6 122.6 75.2 20.1 43.1 25.1 13.3 32.9 57.1 73.2 2.5 0.4 24.6 21.5 114.9 58.0 70.2 32.1 81.2 ARMH3 "C10orf76, FLJ13114" ENSG00000120029 "Armadillo like helical domain containing 3" Q5T2E6 10 101845599-102056193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.2;dendritic cells: 10.5;Extravillous trophoblasts: 14.8;Granulosa cells: 11.5;Hofbauer cells: 12.6;Syncytiotrophoblasts: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050913, HPA053580" Approved Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA050913: AB_2681270, HPA053580: AB_2682198" "unprognostic (5.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "unprognostic (3.41e-2)" "unprognostic (9.41e-2)" "unprognostic (9.55e-2)" "unprognostic (5.28e-2)" "unprognostic (1.92e-2)" "unprognostic (1.18e-1)" "unprognostic (6.03e-3)" "unprognostic (1.40e-3)" "unprognostic (2.76e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-1)" "unprognostic (2.48e-1)" "unprognostic (3.85e-1)" "unprognostic (4.87e-2)" 10.4 9.1 5.9 12.0 7.6 21.8 9.9 10.2 7.3 11.2 8.0 12.5 12.8 10.5 9.4 14.3 10.5 9.2 16.6 5.7 7.3 10.0 12.0 11.8 12.7 7.1 8.2 11.2 10.1 16.4 7.9 11.0 6.1 10.8 13.2 16.3 9.5 10.5 19.7 12.2 12.2 12.9 6.0 13.6 10.3 8.9 6.7 13.1 10.0 19.8 13.3 10.8 10.1 7.9 23.2 17.7 15.5 19.1 12.9 17.3 13.9 20.3 24.0 20.0 16.9 12.2 18.6 17.0 13.5 22.9 14.5 17.7 20.4 22.4 18.3 17.9 18.9 30.3 15.9 14.6 15.2 21.3 26.4 16.0 17.7 22.6 19.9 23.4 15.3 15.3 0.9 15.9 16.6 14.4 16.5 13.8 8.5 18.8 11.6 16.0 28.1 11.0 16.4 18.6 7.3 12.1 15.8 10.9 21.0 15.8 28.8 12.4 15.1 10.5 17.1 9.8 14.7 15.4 17.0 17.1 16.9 23.7 7.9 19.4 7.3 7.4 5.9 8.7 5.5 6.1 6.2 4.5 7.7 7.0 4.8 4.9 1.9 5.2 10.7 7.4 6.0 4.7 5.9 7.6 10.2 7.3 5.7 7.3 7.1 8.2 6.1 6.0 6.7 7.9 8.8 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 7.4 6.0 0.0 0.0 0.0 0.0 0.0 11.2 10.5 0.0 1.9 7.8 0.0 6.9 6.8 1.9 0.0 0.0 0.0 9.7 14.8 2.7 0.0 7.7 0.0 11.5 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 9.9 0.0 0.0 2.2 0.0 0.0 7.6 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 16.3 3.9 5.7 0.0 0.0 ARPC2 "ARC34, p34-Arc" ENSG00000163466 "Actin related protein 2/3 complex subunit 2" O15144 2 218217141-218254356 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001994, HPA008352, HPA052703" Approved Supported Nucleoplasm NA NA 6600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "CAB001994: , HPA008352: AB_1854887, HPA052703: " "unprognostic (7.42e-2)" "unprognostic (4.07e-1)" "unprognostic (1.50e-1)" "unprognostic (3.28e-3)" "unprognostic (2.77e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.23e-2)" "unprognostic (1.90e-2)" "unprognostic (4.07e-2)" "unprognostic (3.95e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (1.07e-7)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (1.01e-2)" "unprognostic (7.41e-2)" 205.4 121.8 114.0 361.4 125.6 544.1 163.5 109.4 130.8 163.1 117.4 252.8 200.3 153.3 161.8 460.5 146.3 211.3 167.3 135.2 123.1 155.0 152.8 259.7 505.2 115.1 114.7 121.3 122.1 115.4 94.7 295.0 116.4 132.1 274.8 77.4 163.6 176.0 385.3 293.4 226.5 291.2 117.8 294.6 251.5 149.7 118.2 298.3 115.3 250.8 626.0 402.0 231.7 125.4 438.3 188.3 264.1 198.0 346.6 463.6 489.4 680.5 640.7 551.2 549.5 588.6 452.0 358.6 347.6 764.7 396.8 492.3 362.6 985.4 645.4 284.2 296.5 362.1 279.0 325.8 386.8 764.2 968.9 310.2 784.1 552.0 454.6 515.1 731.3 294.1 179.5 681.4 858.6 304.3 416.8 888.6 310.8 500.8 201.1 307.2 235.0 488.7 556.8 787.8 156.3 278.8 246.7 265.8 590.0 544.4 192.7 689.2 642.1 709.5 268.1 321.9 507.8 359.8 418.8 624.7 515.1 472.9 548.2 1728.0 1318.5 1975.5 930.7 1773.7 626.1 785.9 720.7 913.6 1330.1 658.5 505.7 750.0 2200.3 698.9 2060.4 734.3 1039.0 2503.2 114.0 125.6 109.4 130.8 135.2 123.1 115.1 114.7 116.4 117.8 118.2 125.4 334.8 285.2 326.6 21.2 506.7 928.5 691.0 1140.2 425.2 89.8 150.3 189.7 145.3 200.1 465.4 172.9 56.3 944.5 902.3 595.0 342.4 585.8 604.0 220.6 288.5 363.5 319.7 144.9 48.5 658.7 1509.4 301.7 242.6 222.4 414.5 600.6 281.3 98.4 1094.0 58.9 33.1 329.4 364.2 779.9 1321.0 759.3 214.0 896.1 414.4 53.4 1721.9 175.3 1336.7 30.7 33.7 919.8 604.5 326.5 529.9 762.7 510.9 342.8 249.6 95.3 302.4 131.6 571.2 324.4 227.9 645.2 970.6 1045.8 694.1 285.6 337.6 1126.5 ARPP21 "ARPP-21, R3HDM3, TARPP" ENSG00000172995 "CAMP regulated phosphoprotein 21" Q9UBL0 3 35638945-35794496 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 260.8;lymphoid tissue: 170.1;skeletal muscle: 85.6" "Group enriched" "Detected in some" 6 "Excitatory neurons: 861.9;Oligodendrocyte precursor cells: 624.8" "Cancer enriched" "Detected in single" 5 "glioma: 1.3" "Region enhanced" "Detected in many" "basal ganglia: 260.8" "Immune cell enriched" "Detected in single" 30 "plasmacytoid DC: 10.1" "Lineage enriched" "Detected in single" 30 "dendritic cells: 10.1" "Cell line enhanced" "Detected in some" "JURKAT: 111.4;MOLT-4: 68.4;REH: 37.3;RH-30: 20.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 254.3" HPA017303 Enhanced Supported Approved Nucleoli,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli Cytosol "HPA017303: AB_1845049" "unprognostic (1.72e-4)" "unprognostic (2.35e-1)" "unprognostic (1.10e-2)" "unprognostic (6.61e-2)" "unprognostic (6.30e-3)" "unprognostic (8.90e-2)" "unprognostic (2.42e-3)" "unprognostic (1.27e-1)" "unprognostic (7.42e-4)" "unprognostic (1.32e-1)" "unprognostic (2.35e-1)" "unprognostic (1.52e-1)" 0.2 0.2 34.8 0.4 260.8 4.5 0.1 85.2 69.9 0.0 0.0 0.4 0.2 0.0 0.0 2.6 0.0 0.0 0.2 48.5 15.7 1.1 2.3 0.1 0.1 14.3 7.8 0.0 0.1 0.0 12.6 0.0 15.6 1.1 0.4 2.9 2.1 0.2 85.6 0.2 0.3 0.0 0.0 0.2 0.2 0.0 9.1 170.1 0.5 48.6 0.4 0.0 0.0 44.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.6 0.0 5.2 0.0 0.0 0.0 0.6 0.0 111.4 0.0 0.2 2.6 0.0 68.4 0.0 0.1 0.0 2.7 37.3 20.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 0.0 0.0 34.8 260.8 85.2 69.9 48.5 15.7 14.3 7.8 15.6 0.0 9.1 44.5 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.8 0.0 0.2 0.2 0.0 0.0 861.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 108.2 0.0 0.0 0.0 0.0 3.5 0.3 0.1 0.0 21.5 0.1 0.0 0.0 624.8 85.7 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.5 0.0 21.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 ASB1 ASB-1 ENSG00000065802 "Ankyrin repeat and SOCS box containing 1" Q9Y576 2 238426742-238452250 "Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003508 Uncertain Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA003508: AB_1845065" "unprognostic (1.02e-1)" "unprognostic (5.30e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (4.89e-5)" "unprognostic (4.04e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.49e-2)" "unprognostic (5.81e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.56e-4)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" "unprognostic (2.19e-1)" 6.6 5.5 19.1 7.3 18.8 2.9 5.3 14.6 18.1 8.9 9.7 10.1 3.9 10.7 3.7 5.0 8.6 5.3 16.2 17.0 18.6 6.2 6.4 6.4 8.0 18.1 20.0 10.2 5.9 8.4 7.6 3.2 19.5 7.5 4.7 5.5 5.4 7.9 21.1 5.7 8.3 8.1 18.9 7.8 8.0 10.7 19.3 6.7 5.8 23.3 8.5 8.1 6.5 17.1 11.1 15.7 21.2 17.0 13.3 14.0 17.1 29.9 19.8 17.7 19.8 7.7 7.7 9.6 4.0 28.2 39.3 12.0 21.1 47.7 27.7 24.3 17.2 12.1 15.2 19.3 31.1 16.8 15.5 15.0 21.7 51.7 69.7 27.8 7.7 16.7 25.9 6.3 32.9 7.6 9.2 17.8 22.6 9.7 13.2 13.3 43.1 6.4 12.9 15.1 17.1 23.2 9.4 6.9 15.7 12.7 5.2 17.9 16.6 31.8 20.6 25.1 59.9 22.8 15.2 16.5 50.2 5.3 16.2 0.0 0.5 1.0 4.2 0.7 2.2 4.3 3.0 4.1 0.6 2.1 2.5 3.0 0.2 2.1 0.4 2.8 4.1 1.3 19.1 18.8 14.6 18.1 17.0 18.6 18.1 20.0 19.5 18.9 19.3 17.1 2.3 9.6 3.7 7.8 12.2 7.9 27.5 16.4 7.4 10.0 7.4 7.1 45.3 15.7 11.3 9.2 4.2 12.3 12.8 5.2 1.9 15.8 35.2 9.8 8.1 4.0 12.7 19.1 6.1 21.0 28.6 15.0 14.8 4.6 15.9 7.6 5.0 12.5 23.7 10.1 6.1 6.6 10.2 9.5 4.3 19.5 7.8 10.4 7.2 3.7 12.3 9.8 11.3 6.6 8.5 30.4 16.3 14.7 18.5 20.1 8.4 11.3 18.4 6.5 26.3 10.6 16.0 52.1 37.4 7.2 6.8 5.7 13.9 9.9 7.1 15.4 ASCL4 "bHLHa44, HASH4" ENSG00000187855 "Achaete-scute family bHLH transcription factor 4" Q6XD76 12 107774385-107776644 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Langerhans cells: 3.1" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA036116 Uncertain NA NA "Cluster 41: Macrophages - Immune response" "HPA036116: AB_10671833" "unprognostic (2.20e-1)" "unprognostic (1.53e-4)" "unprognostic (1.86e-2)" "unprognostic (8.88e-4)" "unprognostic (2.09e-5)" "unprognostic (1.40e-1)" "unprognostic (1.88e-2)" "unprognostic (1.48e-1)" "unprognostic (1.88e-3)" "unprognostic (9.25e-2)" "unprognostic (1.80e-1)" "unprognostic (2.90e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ASIC2 "ACCN, ACCN1, ASIC2a, BNaC1, BNC1, hBNaC1, MDEG" ENSG00000108684 "Acid sensing ion channel subunit 2" Q16515 17 33013087-34174964 "Plasma proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 13.0;cervix: 3.4;endometrium 1: 3.4;retina: 4.6" "Group enriched" "Detected in some" 8 "Excitatory neurons: 1786.2;Inhibitory neurons: 666.4" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.0;RPTEC TERT1: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052112 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA052112: AB_2681733" "unprognostic (3.40e-1)" "unprognostic (2.45e-2)" "unprognostic (8.50e-2)" "unprognostic (7.33e-2)" "unprognostic (1.88e-3)" "unprognostic (5.29e-2)" "unprognostic (4.88e-2)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.29e-2)" "unprognostic (1.28e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" 0.0 0.6 13.0 0.0 11.4 0.0 0.1 4.4 10.3 3.4 0.0 0.1 0.4 3.4 0.0 0.0 0.6 0.0 0.0 12.4 6.0 1.1 0.0 0.0 0.0 6.2 6.0 0.0 0.0 0.0 0.5 0.0 3.3 0.1 0.1 4.6 0.0 0.5 0.0 0.1 0.3 1.4 5.8 0.0 0.0 0.3 6.2 0.0 0.0 0.0 0.0 0.0 0.1 8.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 11.4 4.4 10.3 12.4 6.0 6.2 6.0 3.3 5.8 6.2 8.2 0.0 0.0 0.0 17.0 0.0 0.3 0.0 0.0 0.0 25.7 0.0 0.0 1.3 0.0 0.0 9.2 2.1 0.0 0.0 0.1 0.0 0.1 16.3 0.1 0.8 0.1 6.0 0.0 1786.2 0.0 0.0 0.3 0.0 0.4 0.0 0.2 0.0 0.0 0.1 10.1 666.4 1.3 0.0 0.0 0.0 47.1 0.3 0.1 1.8 26.2 0.0 0.5 0.0 144.3 22.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.0 0.2 0.3 0.6 0.0 0.0 0.0 0.1 0.0 1.2 0.0 ASIP "AGTIL, ASP" ENSG00000101440 "Agouti signaling protein" P42127 20 34194569-34269344 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 14.8;heart muscle: 28.0;ovary: 41.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.4;dendritic cells: 44.1;Hofbauer cells: 15.1;Leydig cells: 12.5;Peritubular cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 356 "plasmacytoid DC: 134.8" "Lineage enriched" "Detected in single" 356 "dendritic cells: 134.8" "Cell line enhanced" "Detected in some" "CACO-2: 3.2;HSkMC: 2.4;SK-MEL-30: 1.9;U-698: 1.9" "Not detected" "Not detected" HPA048636 Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA048636: AB_2680471" "unprognostic (4.81e-2)" "unprognostic (7.46e-2)" "unprognostic (1.97e-3)" "unprognostic (3.26e-2)" "unprognostic (2.24e-1)" "unprognostic (3.07e-2)" "unprognostic (5.13e-2)" "unprognostic (4.57e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (5.53e-6)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" 1.4 0.6 0.2 0.0 0.5 0.3 2.4 0.1 0.4 4.2 0.0 0.5 0.0 2.0 14.8 0.1 4.0 0.1 28.0 0.1 0.1 0.9 1.3 0.3 0.4 0.2 0.1 41.7 0.1 0.0 0.6 0.2 0.6 1.5 0.0 0.3 0.7 0.2 0.9 5.7 0.8 0.0 0.0 0.3 0.3 1.5 0.2 0.2 0.3 1.2 0.5 0.5 1.1 0.3 0.0 1.1 0.4 0.4 0.2 0.7 0.1 0.1 0.0 0.0 0.0 3.2 0.0 1.2 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.7 0.3 0.5 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.1 0.0 0.7 0.6 0.9 0.0 0.3 0.2 1.7 0.0 0.1 0.6 0.3 0.3 1.4 0.0 0.1 0.2 0.2 0.0 0.2 1.9 0.5 0.3 0.2 0.3 0.5 0.5 0.0 0.3 0.4 0.4 1.9 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 134.8 0.0 0.6 0.2 0.5 0.1 0.4 0.1 0.1 0.2 0.1 0.6 0.0 0.2 0.3 0.4 0.0 0.6 1.3 0.8 2.5 0.0 0.0 0.0 0.0 0.3 0.5 27.4 0.0 0.0 0.0 0.0 0.2 44.1 0.0 1.9 0.0 1.1 0.3 9.2 1.2 0.0 0.0 2.1 0.0 0.2 5.6 0.0 0.4 0.0 0.2 2.5 5.8 15.1 0.0 1.8 0.0 0.0 0.8 7.0 1.7 12.5 2.1 1.8 1.0 0.3 0.0 0.0 2.5 2.5 0.1 0.0 10.5 0.0 0.1 0.0 8.3 0.0 0.0 6.6 0.1 0.6 1.7 1.9 0.2 3.1 0.8 0.6 1.0 0.0 0.1 ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.3;smooth muscle: 110.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 67.2;Fibroblasts: 94.6;Microglial cells: 24.4;Sertoli cells: 39.5;Smooth muscle cells: 73.5;Suprabasal keratinocytes: 27.0" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Cell line enhanced" "Detected in some" "ASC TERT1: 16.0;BJ hTERT+: 5.7;HHSteC: 23.2;HSkMC: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 2100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" 29.6 7.6 1.2 5.7 1.7 0.1 11.8 2.3 2.0 40.9 0.9 25.5 9.6 69.6 9.7 10.1 16.9 65.9 95.3 1.2 1.2 11.2 41.1 14.3 3.0 1.3 1.2 7.1 13.4 3.8 2.5 4.3 1.6 4.7 11.3 0.2 3.2 11.7 7.8 12.1 17.6 110.5 1.0 2.3 12.0 1.2 1.8 2.5 11.1 19.8 5.5 13.4 5.0 1.7 0.1 0.0 0.0 0.0 1.4 16.0 0.2 2.6 5.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 23.2 0.2 0.0 4.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 1.2 1.7 2.3 2.0 1.2 1.2 1.3 1.2 1.6 1.0 1.8 1.7 12.9 0.0 1.1 0.3 0.1 67.2 0.1 0.0 0.0 0.4 0.4 0.1 8.5 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 4.2 6.8 0.0 0.0 2.0 0.0 0.1 94.6 0.5 0.2 1.3 0.1 13.9 0.4 0.2 0.0 1.7 0.0 0.0 0.0 13.5 0.6 5.9 0.8 14.2 24.4 0.0 0.1 0.0 1.5 1.1 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.7 0.6 39.5 4.3 73.5 0.0 0.1 0.3 27.0 0.0 1.7 0.3 0.0 0.0 ATF6 ATF6A ENSG00000118217 "Activating transcription factor 6" P18850 1 161766298-161977574 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005935 Approved NA NA 46000000 "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "HPA005935: AB_2667472" "unprognostic (1.31e-1)" "unprognostic (5.15e-3)" "unprognostic (3.18e-2)" "unprognostic (8.43e-3)" "unprognostic (1.59e-1)" "unprognostic (5.58e-3)" "unprognostic (1.24e-1)" "unprognostic (5.32e-2)" "unprognostic (3.37e-2)" "unprognostic (3.24e-1)" "unprognostic (6.09e-3)" "unprognostic (3.38e-1)" "unprognostic (7.55e-2)" "unprognostic (2.03e-1)" "unprognostic (2.43e-1)" "unprognostic (1.56e-2)" "unprognostic (7.57e-3)" 13.6 10.1 7.2 13.9 8.4 12.6 11.5 8.3 7.5 8.4 13.6 9.9 9.9 10.6 18.9 11.0 8.9 11.3 9.4 7.2 9.9 14.6 22.0 11.4 10.6 10.2 9.4 9.0 34.4 18.9 7.1 18.0 10.5 10.7 11.2 16.7 13.3 10.3 8.9 11.2 9.4 12.8 10.0 11.3 11.2 10.1 8.0 8.4 15.1 9.5 11.1 13.7 7.9 11.9 23.3 17.9 15.1 22.4 18.6 17.7 26.7 27.8 25.3 17.7 19.2 11.6 38.2 16.9 39.6 34.6 19.9 34.0 15.1 18.6 17.6 23.2 12.9 15.9 22.6 12.7 40.3 29.7 40.6 18.3 29.0 18.2 53.3 23.8 40.3 22.7 37.9 19.2 19.3 23.0 15.9 17.3 12.2 24.5 23.1 13.7 21.4 39.2 19.3 11.1 9.1 13.8 33.3 19.8 41.0 32.9 24.5 39.2 54.4 23.2 21.9 8.7 31.5 28.0 29.2 20.4 28.2 5.1 29.0 9.7 17.8 12.0 9.2 18.3 9.0 8.7 8.3 7.7 12.8 9.5 9.5 9.7 33.2 7.4 24.4 5.7 9.6 10.6 7.2 8.4 8.3 7.5 7.2 9.9 10.2 9.4 10.5 10.0 8.0 11.9 40.5 102.5 85.1 41.8 31.4 34.8 45.4 28.4 18.2 38.6 38.0 25.4 21.6 25.8 67.0 51.5 50.1 49.2 23.2 30.5 7.9 45.9 13.0 27.1 25.3 49.8 37.1 17.9 79.9 37.6 43.1 46.2 23.9 40.2 54.3 24.0 37.5 53.5 50.3 26.9 69.7 28.2 30.5 59.5 59.4 10.8 23.0 66.6 26.6 103.0 62.0 34.1 21.6 60.3 105.8 35.9 15.6 24.5 53.9 43.3 22.3 18.8 61.7 29.9 6.6 61.3 31.8 43.1 30.5 22.7 47.7 103.0 29.0 22.1 22.9 44.1 ATG2A KIAA0404 ENSG00000110046 "Autophagy related 2A" Q2TAZ0 11 64894546-64917211 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 16.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038715 Uncertain Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "HPA038715: AB_10673474" "unprognostic (3.05e-2)" "unprognostic (2.33e-1)" "unprognostic (7.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.42e-1)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.79e-5)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (3.37e-1)" "unprognostic (1.15e-1)" 16.4 20.1 11.4 6.5 10.9 60.2 16.9 8.6 40.1 19.9 11.4 18.9 7.5 18.2 1.8 15.7 19.2 4.2 18.4 11.5 9.8 22.0 59.2 24.2 6.1 13.9 12.3 24.9 22.7 4.9 21.6 4.9 12.7 21.6 2.6 1.9 15.2 5.7 26.7 34.9 21.4 3.3 9.0 25.7 23.2 15.3 11.4 5.4 19.3 4.4 3.3 17.7 15.6 10.4 13.2 12.6 4.4 12.0 5.7 4.0 12.3 7.1 10.3 9.4 6.8 11.0 9.9 9.3 14.7 6.0 12.0 10.8 4.5 8.3 2.5 9.1 15.7 8.7 19.1 10.0 8.4 6.5 18.2 10.9 7.1 11.8 6.3 5.4 7.9 9.5 16.1 7.3 4.1 21.3 7.8 21.9 5.1 3.5 14.3 8.6 7.1 13.5 5.0 10.9 16.5 6.7 10.6 14.6 13.3 3.3 14.3 8.1 10.1 9.0 8.6 18.3 5.3 14.7 5.5 6.5 13.0 5.2 5.6 3.0 2.0 2.2 2.5 2.1 2.1 0.8 1.7 2.2 1.4 0.9 1.3 2.4 16.9 1.8 1.7 2.4 0.9 1.2 11.4 10.9 8.6 40.1 11.5 9.8 13.9 12.3 12.7 9.0 11.4 10.4 9.8 9.6 16.2 20.2 17.0 28.9 8.7 35.7 16.5 16.6 15.8 10.3 8.1 7.2 17.6 9.2 33.3 12.7 40.1 38.8 1.9 10.2 2.5 12.4 9.2 10.2 35.9 16.2 7.6 10.3 5.3 12.6 16.8 24.4 9.5 15.4 7.9 23.2 10.9 13.5 8.4 17.6 24.4 20.1 19.9 3.6 12.8 24.2 30.2 5.6 11.9 12.3 19.6 6.6 7.1 14.9 21.7 10.1 27.3 12.2 26.8 6.6 13.3 26.0 13.1 11.6 10.6 9.0 6.2 16.3 38.4 66.9 40.2 27.2 19.0 15.9 ATG9B "APG9L2, FLJ14885, NOS3AS, SONE" ENSG00000181652 "Autophagy related 9B" Q674R7 7 151012209-151024499 "Metabolic proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 8.3;skin 1: 11.5" "Cell type enhanced" "Detected in many" "Early spermatids: 50.7;Endometrial ciliated cells: 28.6;Late spermatids: 30.3;Respiratory ciliated cells: 25.9;Syncytiotrophoblasts: 115.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.9" "Lineage enriched" "Detected in many" 5 "T-cells: 8.9" "Group enriched" "Detected in some" 5 "BEWO: 13.0;CAPAN-2: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.59e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (1.53e-3)" "unprognostic (1.05e-3)" "unprognostic (2.79e-3)" "unprognostic (6.66e-2)" "unprognostic (2.38e-3)" "unprognostic (6.76e-2)" "unprognostic (2.02e-1)" "unprognostic (5.06e-2)" "unprognostic (2.08e-6)" "unprognostic (2.82e-2)" "unprognostic (2.70e-2)" "unprognostic (6.34e-2)" "unprognostic (2.63e-1)" 0.0 0.5 1.1 0.4 1.7 0.2 0.2 0.4 1.0 1.7 0.3 0.0 0.0 0.4 1.1 8.3 1.0 0.2 0.0 0.5 2.1 0.0 0.0 0.2 0.8 2.0 1.7 0.1 0.0 0.0 1.5 4.1 1.1 0.2 0.0 0.8 0.5 0.0 0.2 11.5 0.0 0.0 1.0 0.1 0.1 2.0 2.1 0.3 0.1 0.0 0.8 0.1 1.6 0.4 0.6 0.0 0.7 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.1 4.2 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.6 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.5 0.4 0.6 0.0 1.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 1.1 0.0 1.0 0.9 5.0 1.3 0.0 1.6 8.9 3.4 0.0 0.4 0.1 0.7 5.4 1.4 1.1 1.7 0.4 1.0 0.5 2.1 2.0 1.7 1.1 1.0 2.1 0.4 0.4 0.0 0.0 0.0 2.8 0.0 0.2 1.9 0.6 4.0 0.7 0.9 1.4 1.5 1.6 0.0 0.0 10.2 1.5 0.3 0.0 0.3 50.7 28.6 3.3 1.1 0.0 0.0 2.7 0.2 2.5 0.5 0.0 15.4 14.7 7.8 2.2 0.0 1.9 0.0 7.7 0.0 4.1 0.3 0.4 30.3 0.6 0.8 0.0 0.0 0.3 0.5 1.0 0.5 0.6 3.8 0.0 0.7 0.4 0.3 0.0 0.1 25.9 0.6 0.0 0.0 0.9 19.8 12.7 0.8 0.3 115.5 4.7 0.1 0.2 1.9 ATOH8 "bHLHa21, FLJ14708, HATH6" ENSG00000168874 "Atonal bHLH transcription factor 8" Q96SQ7 2 85751344-85791383 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 54.7" "Cell type enhanced" "Detected in many" "Adipocytes: 123.8;Endothelial cells: 41.7;Hepatocytes: 39.1;Muller glia cells: 32.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 15.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.2;fHDF/TERT166: 6.8;hTERT-RPE1: 5.0;RH-30: 9.5;RT4: 5.6;TIME: 7.9;U-2197: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028406 Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA028406: AB_2672587" "unprognostic (7.70e-2)" "unprognostic (1.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (2.84e-3)" "unprognostic (2.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.78e-1)" "unprognostic (6.28e-3)" "unprognostic (1.56e-1)" "prognostic favorable (8.98e-6)" "unprognostic (3.32e-2)" "prognostic favorable (3.80e-5)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-2)" 33.8 1.8 2.1 0.3 2.2 0.0 29.9 2.7 1.6 20.9 0.5 8.8 0.2 25.9 0.2 5.6 19.4 0.4 30.6 1.5 5.1 7.3 25.1 25.6 0.8 5.7 4.9 15.0 4.2 0.2 5.4 0.3 5.3 17.4 0.4 0.6 5.2 1.9 54.7 19.9 8.9 1.3 1.6 12.2 9.4 2.1 3.1 0.2 48.5 2.0 0.1 21.7 20.6 3.3 0.0 1.1 4.1 6.2 3.0 0.4 0.0 3.4 0.5 0.8 0.3 0.0 0.0 0.0 1.1 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.1 1.6 0.0 0.0 2.1 0.0 0.0 0.0 5.0 0.6 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 9.5 0.0 0.0 5.6 3.0 1.4 0.6 0.0 0.6 0.0 0.0 0.0 7.9 1.2 0.0 5.5 0.0 0.0 0.0 0.0 0.8 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.2 2.7 1.6 1.5 5.1 5.7 4.9 5.3 1.6 3.1 3.3 123.8 9.6 18.3 10.7 0.3 2.5 8.5 11.8 0.6 0.4 0.5 0.8 13.2 5.7 17.5 1.8 0.0 0.1 0.1 1.1 0.0 11.9 13.6 5.9 5.7 41.7 4.2 0.0 0.3 2.3 0.6 11.4 1.1 20.5 1.3 5.3 5.7 39.1 3.2 0.0 0.3 2.2 6.1 3.1 4.0 25.9 3.4 4.3 1.8 5.6 0.6 32.3 0.0 14.6 3.1 1.0 5.5 0.4 0.0 4.5 0.0 0.6 2.4 1.3 0.0 12.2 11.6 3.0 2.7 0.2 1.4 0.3 0.5 0.1 1.0 2.3 ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677271-25865184 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0" "Cell type enriched" "Detected in many" 6 "Microglial cells: 216.4" "Cancer enhanced" "Detected in all" "melanoma: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 23.0;fHDF/TERT166: 22.9;HMC-1: 19.4;SK-MEL-30: 21.9;U-2197: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041496: AB_2677513, HPA042509: AB_2678032" "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" 6.5 8.7 13.7 2.7 9.3 2.5 5.3 6.0 8.9 2.0 0.7 3.2 0.8 1.5 0.1 1.9 2.3 3.7 2.0 5.9 5.8 5.8 0.6 7.1 1.8 9.9 9.7 1.1 1.4 3.5 2.1 1.7 9.5 2.2 0.8 0.1 7.9 0.6 0.6 2.5 3.0 2.8 5.9 1.5 3.2 4.3 15.0 1.1 2.5 0.7 1.1 2.5 1.4 4.9 0.0 5.7 1.3 0.0 2.2 2.8 0.0 23.0 9.3 6.1 9.9 0.0 0.0 0.0 1.6 22.9 0.0 0.0 9.3 1.2 0.4 0.0 0.2 0.0 0.0 0.1 0.1 0.0 19.4 0.9 0.0 0.6 0.0 2.5 0.0 1.2 0.0 0.0 3.3 0.0 1.2 0.0 1.5 0.0 1.5 4.4 4.6 2.8 9.9 0.0 0.0 0.1 0.0 0.0 21.9 0.0 7.4 1.2 0.0 8.9 0.2 12.7 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.3 0.5 0.1 0.0 0.7 0.6 0.0 1.2 0.0 1.0 0.1 0.3 13.7 9.3 6.0 8.9 5.9 5.8 9.9 9.7 9.5 5.9 15.0 4.9 0.3 32.1 8.6 2.0 0.8 1.0 0.0 2.7 0.6 0.2 2.6 1.8 1.7 1.5 5.3 0.0 0.0 0.0 11.1 0.1 0.0 0.5 23.2 2.8 2.8 4.2 0.0 0.0 4.5 0.0 0.1 5.0 3.1 7.9 15.2 0.0 0.4 0.1 2.5 0.0 2.1 0.2 0.0 2.5 5.2 21.8 4.1 4.5 17.8 216.4 2.3 0.0 14.4 1.5 2.7 0.8 0.0 17.7 1.7 0.7 0.0 0.1 4.2 0.1 0.0 4.7 9.1 0.4 1.2 0.0 0.4 0.0 8.6 0.1 0.0 0.0 ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.1;gallbladder: 16.6;intestine: 45.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 136.4;Oligodendrocyte precursor cells: 293.0;Oligodendrocytes: 419.4;Undifferentiated cells: 90.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 13.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034574 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA034574: AB_10669992" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.47e-4)" "unprognostic (3.99e-2)" "unprognostic (6.10e-3)" "unprognostic (4.69e-2)" "unprognostic (4.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-2)" "unprognostic (3.42e-2)" "unprognostic (5.12e-2)" "unprognostic (2.38e-3)" "unprognostic (5.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-1)" "unprognostic (2.14e-1)" 0.1 0.0 4.1 5.0 9.0 0.0 0.4 8.8 6.4 1.0 0.1 44.5 24.7 0.0 12.3 6.2 0.4 16.6 0.0 4.3 5.0 0.1 0.0 0.0 0.0 10.6 7.8 0.0 2.9 0.0 0.0 0.0 9.9 0.0 45.7 0.0 1.8 0.7 0.0 7.1 21.0 1.5 5.8 0.0 4.8 0.3 8.0 5.0 0.0 0.0 2.9 1.5 2.5 17.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.1 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 9.0 8.8 6.4 4.3 5.0 10.6 7.8 9.9 5.8 8.0 17.1 0.1 0.0 0.0 42.7 0.6 0.4 0.1 12.9 0.0 0.0 0.1 0.0 1.2 21.5 15.1 1.8 0.0 0.0 0.0 136.4 0.0 23.6 0.2 0.2 0.0 0.3 13.2 0.0 4.0 20.3 0.1 0.0 10.7 0.3 0.0 0.0 0.0 0.3 0.1 0.0 3.9 55.4 4.1 0.0 1.2 0.6 0.0 0.1 1.8 1.9 1.6 0.0 0.0 293.0 419.4 16.4 64.7 0.0 0.4 0.1 24.1 0.0 16.0 0.0 0.0 0.0 0.6 0.0 0.1 2.9 0.9 0.5 0.3 0.0 90.7 6.5 ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485275-47593486 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "basophil: 84.3" "Lineage enriched" "Detected in all" 12 "granulocytes: 84.3" "Cell line enhanced" "Detected in many" "HAP1: 41.6" "Low region specificity" "Detected in all" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Plasma membrane" "HPA050808: AB_2681242" "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.93e-2)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-2)" "unprognostic (8.05e-2)" "unprognostic (3.48e-2)" "unprognostic (3.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "prognostic favorable (5.00e-8)" "unprognostic (3.97e-2)" "unprognostic (4.47e-3)" "unprognostic (1.11e-2)" "unprognostic (3.37e-2)" 4.9 6.0 2.6 5.0 2.9 1.3 4.2 1.9 2.7 7.0 15.9 3.7 3.9 7.4 7.2 10.2 4.7 7.4 4.2 1.8 4.1 10.2 2.4 6.1 6.2 3.1 3.7 8.1 4.5 10.4 3.1 14.9 2.9 4.6 3.8 4.1 3.4 6.4 1.0 9.9 4.5 9.7 2.4 10.0 5.1 2.0 5.0 4.5 9.1 2.7 7.9 7.3 6.5 2.9 2.6 1.8 4.0 2.8 11.1 12.0 0.7 17.9 21.5 8.4 15.1 9.4 15.4 8.1 6.5 29.1 14.3 4.6 41.6 15.0 12.9 3.2 3.2 6.5 2.8 0.5 9.8 2.1 3.9 10.3 11.2 16.4 10.9 27.5 14.4 4.0 0.1 4.3 23.2 1.0 4.4 1.2 1.4 0.0 2.2 4.9 9.0 0.1 15.0 3.1 2.6 4.9 8.4 2.1 5.2 8.7 3.8 2.1 21.9 20.7 4.1 1.9 7.8 1.9 1.5 0.0 10.2 11.9 6.8 84.3 3.1 0.4 1.1 5.0 1.9 2.7 0.5 0.8 4.0 6.7 0.1 0.9 1.5 2.3 6.9 2.4 0.8 1.6 2.6 2.9 1.9 2.7 1.8 4.1 3.1 3.7 2.9 2.4 5.0 2.9 22.9 9.6 7.5 39.2 27.8 19.2 9.2 21.9 23.9 12.2 6.7 8.4 4.9 4.3 8.5 16.5 31.3 48.5 17.1 1.6 1.9 5.5 4.4 4.8 29.5 16.1 9.6 4.0 25.7 4.6 11.0 22.4 14.3 7.0 2.5 21.3 18.2 6.6 13.0 13.5 42.8 4.6 18.3 21.7 7.9 1.5 62.1 17.7 7.2 47.8 15.7 21.9 15.5 52.3 24.1 2.7 3.4 25.2 23.0 5.7 1.9 9.2 6.2 9.2 26.3 12.8 23.6 0.6 2.8 35.4 27.0 176.8 15.5 51.7 4.1 8.1 ATP11B "ATPIF, ATPIR, KIAA0956" ENSG00000058063 "ATPase phospholipid transporting 11B (putative)" Q9Y2G3 3 182793503-182921629 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 132.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036237, HPA036238" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Centriolar satellite, Cytosol" "HPA036237: AB_10673123, HPA036238: AB_10670792" "unprognostic (4.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (6.73e-2)" "unprognostic (2.03e-3)" "unprognostic (7.28e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.09e-4)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (3.22e-1)" "unprognostic (8.66e-2)" "unprognostic (1.35e-1)" 20.6 10.7 4.7 24.9 6.9 70.6 17.4 15.9 7.6 19.1 13.8 26.3 24.3 18.7 14.6 45.4 13.7 21.1 14.1 6.0 6.3 18.0 18.3 16.5 27.9 7.5 6.1 20.5 21.0 29.4 10.3 14.5 7.3 28.3 29.0 30.8 19.4 13.4 11.4 28.2 24.0 19.5 5.6 21.8 51.1 31.6 6.6 44.6 16.8 16.8 28.4 25.7 22.5 15.8 69.7 9.7 20.5 28.7 42.6 46.1 19.3 32.8 41.6 23.2 27.1 23.7 34.0 31.3 53.5 44.0 48.2 40.4 24.6 31.3 40.2 73.9 20.9 76.7 13.1 5.2 24.8 62.3 47.3 31.5 34.7 26.1 37.4 34.1 37.0 48.7 27.7 94.3 37.8 22.9 50.3 19.1 14.5 38.1 19.2 21.2 59.8 37.8 28.1 55.8 12.5 22.0 86.2 10.7 36.9 18.3 11.9 43.7 36.6 35.0 38.7 30.5 56.2 131.0 125.5 58.1 24.1 25.3 20.9 5.5 1.0 4.3 1.7 1.0 1.7 2.1 1.4 1.7 1.1 1.3 1.2 1.8 3.8 1.8 1.0 2.4 1.2 0.8 4.7 6.9 15.9 7.6 6.0 6.3 7.5 6.1 7.3 5.6 6.6 15.8 26.8 16.0 13.2 34.6 27.8 34.3 25.7 15.9 26.2 12.2 13.8 9.7 15.6 18.6 16.5 20.2 14.6 12.8 43.0 44.6 0.0 12.5 34.1 19.0 22.9 15.7 6.7 26.1 81.6 16.5 3.8 19.5 46.4 22.1 11.4 14.0 16.1 16.4 10.4 38.7 64.3 30.5 16.2 19.4 26.4 23.8 19.3 29.3 14.2 45.9 19.9 8.4 27.8 67.8 132.6 25.2 27.0 21.1 55.5 35.8 24.3 7.8 19.8 31.4 19.7 24.1 17.7 18.7 11.4 43.8 44.6 9.6 40.9 7.0 27.3 45.4 ATP11C "ATPIG, ATPIQ" ENSG00000101974 "ATPase phospholipid transporting 11C" Q8NB49 X 139726346-139945276 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 49.8" "Cell type enhanced" "Detected in many" "Spermatocytes: 67.9" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030830 Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA030830: AB_10601336" "unprognostic (8.94e-2)" "unprognostic (1.00e-2)" "unprognostic (3.06e-2)" "unprognostic (3.42e-3)" "unprognostic (3.08e-1)" "unprognostic (3.46e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (3.65e-2)" "unprognostic (9.75e-2)" "unprognostic (2.73e-1)" "unprognostic (5.18e-2)" 13.4 7.4 3.5 9.0 4.2 6.1 10.4 3.6 4.6 11.8 10.3 10.0 5.6 11.9 9.3 5.1 10.7 8.4 5.4 3.1 4.5 11.8 49.8 7.2 14.8 4.9 4.7 12.7 4.9 5.7 3.7 5.3 5.2 9.8 7.1 2.8 6.0 14.6 3.5 6.0 8.6 10.6 3.9 12.2 7.6 9.7 4.8 11.1 6.1 4.3 8.8 13.6 9.3 4.5 16.9 7.1 14.2 23.3 20.7 27.9 18.0 19.7 26.4 15.6 21.5 6.3 13.4 24.0 43.3 28.2 10.3 13.7 34.6 9.0 24.4 22.1 20.2 12.1 15.2 12.3 23.0 21.4 7.4 18.6 5.9 16.9 14.4 17.3 27.3 18.3 14.0 17.9 20.8 9.1 19.7 14.5 24.1 0.1 13.3 19.5 15.3 20.1 13.1 27.6 11.0 18.3 7.8 0.8 10.6 13.3 5.8 11.7 31.0 21.2 6.9 25.9 27.1 5.1 5.4 18.7 9.7 26.3 10.8 2.4 0.4 0.1 0.4 0.3 0.8 0.9 0.4 0.3 0.4 0.9 0.4 0.7 0.9 1.2 0.6 0.7 0.3 0.2 3.5 4.2 3.6 4.6 3.1 4.5 4.9 4.7 5.2 3.9 4.8 4.5 27.4 16.0 8.4 22.5 14.6 14.5 16.7 6.5 5.7 1.9 8.0 8.9 4.4 2.8 9.2 11.0 0.0 2.3 11.6 7.0 1.9 4.8 13.6 11.5 22.7 32.4 9.1 15.3 1.3 10.1 12.6 17.2 10.7 13.7 9.5 23.6 34.6 46.6 9.4 0.0 26.1 6.4 8.2 37.2 14.4 11.9 14.3 15.3 10.6 45.9 33.9 3.1 7.2 29.1 27.8 7.8 7.2 15.4 13.2 15.8 4.7 7.7 6.8 3.1 0.0 19.3 19.2 67.9 53.1 5.9 13.5 6.7 12.7 11.5 5.2 14.6 ATP7A MNK ENSG00000165240 "ATPase copper transporting alpha" Q04656 X 77910656-78050395 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 61.1;Microglial cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012887, HPA048107" Approved Supported "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA012887: AB_1845205, HPA048107: AB_2680266" "unprognostic (3.14e-2)" "unprognostic (3.48e-1)" "unprognostic (4.90e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-3)" "unprognostic (2.59e-2)" "unprognostic (3.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.30e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.38e-4)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (3.69e-1)" "unprognostic (2.52e-1)" 3.0 4.3 1.2 3.6 1.7 5.9 6.3 2.3 2.1 3.9 1.6 3.4 3.9 3.6 5.0 4.9 3.5 3.6 2.5 1.3 2.1 4.4 2.3 4.5 4.1 2.1 2.1 3.6 2.4 7.3 2.5 4.0 3.8 5.3 3.4 3.0 5.1 3.4 1.8 11.1 3.4 3.2 1.1 4.7 5.5 1.6 1.6 4.7 4.6 2.9 4.6 3.9 2.8 2.9 3.2 8.3 5.4 5.5 5.0 5.3 0.9 4.8 6.6 2.8 5.7 1.0 3.6 4.7 6.9 4.8 3.3 3.8 7.1 3.9 5.2 7.0 4.8 2.4 7.8 0.8 6.3 4.1 4.1 5.6 1.6 5.9 1.8 6.5 7.3 4.7 19.6 17.4 5.2 2.8 4.6 1.4 1.5 11.2 1.7 3.7 9.0 15.8 4.6 8.8 1.6 20.4 11.9 2.8 6.0 3.3 2.2 1.3 9.4 3.7 3.6 5.2 1.9 5.6 10.7 5.2 6.0 2.5 5.7 7.1 1.5 4.5 1.8 1.5 0.9 1.8 1.2 1.2 1.0 1.4 1.4 2.1 8.1 1.2 1.9 1.0 0.4 1.0 1.2 1.7 2.3 2.1 1.3 2.1 2.1 2.1 3.8 1.1 1.6 2.9 14.3 0.0 8.4 15.7 12.6 7.4 5.1 5.8 13.1 6.4 17.3 10.0 5.1 1.5 8.2 9.2 4.2 2.0 15.0 4.5 1.9 5.6 0.5 5.3 9.2 9.7 4.8 22.5 11.1 13.6 2.2 9.4 20.4 8.8 9.5 6.4 14.6 3.6 14.3 1.7 12.5 4.8 61.1 11.7 6.7 1.1 7.2 12.6 19.6 44.0 5.5 4.4 11.3 37.7 35.0 6.2 4.1 9.8 10.5 4.8 4.1 5.5 10.2 4.1 32.9 10.3 8.7 1.8 5.4 20.5 16.6 2.2 13.8 6.7 5.2 6.6 ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25371974-26025851 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 21.6;pituitary gland: 15.2;retina: 17.2" "Group enriched" "Detected in many" 6 "Excitatory neurons: 518.7;Inhibitory neurons: 727.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 19.9;JURKAT: 9.8;MOLT-4: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: AB_2676809" "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" 0.1 2.1 5.5 0.3 6.7 0.0 0.6 8.0 21.6 0.2 0.0 0.4 0.3 0.6 1.8 0.0 0.0 0.1 0.1 8.7 19.3 0.3 0.0 0.8 0.6 12.8 4.6 0.2 0.6 0.0 15.2 0.2 12.1 0.1 0.2 17.2 0.1 0.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 2.9 6.6 1.0 0.1 0.1 0.2 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 19.9 0.1 0.0 0.0 0.0 0.6 0.5 9.8 0.0 0.0 1.7 0.1 3.9 0.0 2.0 0.0 0.7 0.0 2.7 0.9 0.2 0.0 3.2 0.0 0.2 0.2 0.1 0.2 0.0 0.4 0.2 0.0 1.0 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.2 0.1 5.5 6.7 8.0 21.6 8.7 19.3 12.8 4.6 12.1 0.2 6.6 6.8 0.7 0.0 12.2 9.4 0.8 1.0 0.2 0.3 0.0 21.5 1.5 0.3 2.5 1.5 0.4 0.0 95.9 1.5 0.4 0.0 0.0 0.3 39.0 1.2 23.6 2.6 0.0 0.8 518.7 0.0 0.4 1.7 1.1 0.9 5.1 3.7 0.0 0.0 3.2 21.9 727.7 0.0 0.0 0.0 0.7 30.3 0.9 0.3 0.0 9.4 0.0 7.2 1.0 88.4 24.7 0.0 0.0 1.2 0.1 0.2 0.0 1.3 0.3 91.6 13.1 0.3 0.8 19.8 12.5 0.0 0.4 1.1 1.8 10.1 0.1 0.1 ATP8B4 "ATPIM, KIAA1939" ENSG00000104043 "ATPase phospholipid transporting 8B4 (putative)" Q8TF62 15 49858238-50182817 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "bone marrow: 78.1" "Cell type enriched" "Detected in many" 6 "Microglial cells: 248.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.2;NK-cell: 11.0" "Group enriched" "Detected in many" 5 "granulocytes: 15.2;NK-cells: 11.0" "Cell line enhanced" "Detected in some" "HMC-1: 40.2;NB-4: 19.2;THP-1: 26.7;U-937: 103.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040254 Approved Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" Cytosol "HPA040254: AB_10673028" "unprognostic (6.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.39e-2)" "unprognostic (2.96e-3)" "unprognostic (3.25e-1)" "unprognostic (6.51e-3)" "unprognostic (1.03e-1)" "unprognostic (4.87e-3)" "unprognostic (1.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.20e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" 1.4 1.1 2.3 2.5 2.4 78.1 0.7 3.5 6.5 1.5 3.0 1.1 0.7 6.4 4.2 0.5 3.1 2.2 0.4 4.5 2.9 1.2 1.6 1.1 1.0 2.5 2.6 0.4 0.5 0.2 0.3 3.5 2.8 0.6 1.7 0.1 0.5 0.8 0.1 0.3 1.3 3.1 3.1 2.6 0.6 0.4 2.4 0.5 0.1 0.1 1.0 1.4 0.4 4.9 0.1 0.6 0.0 0.0 0.0 0.7 0.2 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.5 0.5 0.2 0.0 0.2 12.2 0.0 7.3 1.7 0.1 0.0 13.6 40.2 0.7 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 19.2 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.1 1.5 0.1 1.2 0.0 0.0 0.1 0.0 26.7 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.0 1.3 103.7 0.0 15.2 2.0 3.8 0.4 1.2 0.1 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.8 11.0 0.4 0.0 0.0 0.9 2.3 2.4 3.5 6.5 4.5 2.9 2.5 2.6 2.8 3.1 2.4 4.9 1.7 0.0 1.9 1.6 0.8 1.5 0.1 0.2 0.6 0.6 0.2 0.6 1.3 0.0 0.1 0.0 0.0 5.4 12.5 0.3 0.0 0.0 27.6 0.3 1.7 1.0 0.0 12.2 20.3 0.0 1.8 8.1 3.1 0.2 19.7 0.0 1.1 3.7 16.4 0.0 17.5 0.3 2.0 37.0 17.7 25.3 1.8 27.0 1.8 248.3 6.3 0.5 15.5 1.0 2.1 0.0 0.1 0.7 4.8 2.3 0.7 1.2 0.7 0.2 0.0 1.0 7.0 0.5 0.6 0.6 0.3 2.9 13.4 1.1 0.2 0.3 ATXN7 "ADCAII, OPCA3, SCA7, SGF73" ENSG00000163635 "Ataxin 7" O15265 3 63863155-64003462 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 15.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034989 Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA034989: AB_10602596" "unprognostic (1.51e-2)" "unprognostic (2.44e-1)" "unprognostic (5.98e-2)" "unprognostic (2.18e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.22e-4)" "unprognostic (9.65e-2)" "unprognostic (2.76e-2)" "unprognostic (2.46e-1)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "unprognostic (9.77e-3)" "unprognostic (2.56e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (3.45e-2)" 7.5 6.3 4.5 11.4 4.1 24.4 7.1 4.9 4.4 7.4 0.2 6.9 8.0 8.6 4.7 8.7 6.3 9.6 5.8 3.1 3.7 7.1 8.4 9.0 12.7 3.4 3.3 8.0 21.0 10.9 2.3 8.3 2.7 6.7 8.8 16.3 7.8 5.2 7.1 9.3 9.2 7.9 0.7 10.6 8.4 15.0 3.1 16.5 7.5 8.7 11.7 7.4 4.4 3.2 8.4 5.7 8.1 7.2 8.5 11.3 9.5 6.5 9.0 11.1 10.5 8.9 8.7 12.5 3.1 9.0 12.5 6.5 9.6 9.1 11.9 22.8 4.9 16.1 10.7 4.2 6.4 8.5 17.7 7.9 9.0 15.7 17.7 9.0 8.4 13.3 6.3 26.2 7.7 25.8 12.7 6.8 5.5 5.7 3.0 9.1 7.1 10.1 6.1 11.0 3.1 5.6 13.2 9.4 10.8 6.4 5.1 12.2 11.9 11.4 12.0 12.7 12.9 12.9 13.2 10.3 10.3 11.6 9.4 15.8 1.1 2.1 3.7 1.0 3.3 1.0 6.2 4.0 0.8 2.4 6.2 4.1 4.5 3.5 0.7 1.5 6.2 1.3 4.5 4.1 4.9 4.4 3.1 3.7 3.4 3.3 2.7 0.7 3.1 3.2 2.4 9.6 9.1 34.6 17.0 43.6 24.9 17.6 29.6 73.2 3.4 1.7 10.5 35.8 17.9 5.5 102.2 14.1 21.5 38.3 0.0 2.8 17.1 3.3 1.5 16.1 26.4 29.5 81.2 4.2 13.6 16.6 18.8 3.5 14.7 1.2 26.7 22.8 14.2 25.2 67.0 19.7 24.4 34.6 30.3 9.5 12.8 20.1 12.4 64.6 33.5 24.5 54.6 60.3 46.7 2.5 28.5 13.2 14.8 26.1 28.1 0.7 27.4 70.8 0.0 39.2 15.6 14.8 15.6 25.6 46.2 61.2 41.5 1.6 20.1 38.6 AVEN PDCD12 ENSG00000169857 "Apoptosis and caspase activation inhibitor" Q9NQS1 15 33858782-34075155 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 44.0;Oligodendrocytes: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020863 Approved Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Actin filaments" Centrosome "HPA020863: AB_1845219" "unprognostic (1.54e-3)" "unprognostic (1.99e-1)" "unprognostic (8.93e-2)" "unprognostic (5.77e-2)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (6.32e-3)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (4.14e-3)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.29e-10)" "unprognostic (7.66e-3)" "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (2.84e-3)" 13.7 11.4 8.5 7.2 8.6 4.4 10.8 8.9 10.1 11.4 10.5 15.2 7.4 12.5 5.2 12.3 11.3 6.4 28.5 8.2 9.2 5.5 16.9 7.2 4.8 9.2 9.0 10.5 20.8 3.0 5.8 12.4 9.4 9.4 9.4 2.5 7.9 9.1 31.1 11.2 7.5 12.5 8.8 6.5 12.3 10.7 9.0 6.9 5.6 13.6 7.9 16.2 10.8 9.1 16.4 26.3 26.0 8.6 21.4 24.1 14.7 41.1 36.2 31.9 19.9 7.2 11.3 15.2 24.8 34.8 24.2 10.4 12.2 26.9 25.7 14.6 7.7 26.1 15.9 20.5 31.5 26.6 18.2 19.8 50.9 18.4 45.8 38.6 35.2 7.6 26.6 21.1 45.6 17.3 10.5 46.1 11.9 22.2 8.5 15.7 14.6 32.2 26.4 21.0 13.4 16.8 22.6 11.6 11.4 10.7 12.6 29.4 24.5 27.7 9.5 12.0 34.6 21.2 17.7 31.1 13.3 31.0 15.2 0.0 0.2 0.0 0.5 0.6 0.6 0.4 0.5 0.2 0.2 0.1 0.2 0.3 0.0 0.5 0.2 2.3 0.9 0.1 8.5 8.6 8.9 10.1 8.2 9.2 9.2 9.0 9.4 8.8 9.0 9.1 9.0 3.2 5.3 16.6 5.6 5.7 8.7 1.8 3.4 5.6 7.5 9.0 32.7 2.8 0.8 0.0 6.2 11.0 10.5 7.4 0.0 2.9 13.8 4.4 14.3 10.2 4.8 9.5 21.8 8.6 44.0 8.5 5.6 5.6 0.0 14.7 8.6 19.1 7.4 8.4 24.1 7.7 0.0 4.1 4.4 6.5 7.5 5.0 3.6 22.5 3.5 10.9 7.2 26.7 86.6 7.0 5.2 10.5 15.6 21.5 9.4 4.6 1.5 5.3 6.6 4.9 9.7 6.2 7.4 12.9 9.7 9.4 6.5 23.1 6.0 14.7 B3GALT1 beta3Gal-T1 ENSG00000172318 "Beta-1,3-galactosyltransferase 1" Q9Y5Z6 2 167868948-167874041 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;skeletal muscle: 5.2;tongue: 17.8" "Group enriched" "Detected in some" 6 "Astrocytes: 920.7;Excitatory neurons: 519.3;Inhibitory neurons: 723.8" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "AN3-CA: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.22e-2)" "unprognostic (1.67e-1)" "unprognostic (4.23e-3)" "unprognostic (2.49e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-1)" "unprognostic (3.94e-2)" "unprognostic (8.72e-2)" "unprognostic (6.44e-2)" "unprognostic (2.30e-3)" "unprognostic (8.34e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (3.79e-1)" 0.2 0.5 4.0 0.2 5.4 0.1 0.4 2.0 5.8 0.3 0.0 3.6 0.0 0.2 0.4 0.1 0.6 0.0 0.0 5.8 3.0 0.1 0.0 0.1 0.0 2.4 2.9 0.2 0.3 0.0 1.8 0.0 1.4 0.2 3.6 2.4 0.2 0.7 5.2 0.2 0.2 0.2 2.0 0.2 0.0 0.5 2.6 0.0 0.2 17.8 0.0 0.0 0.2 3.4 0.0 0.0 2.8 35.7 0.3 0.0 0.0 0.5 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 4.6 0.0 1.2 0.0 0.2 0.0 0.5 0.0 2.3 0.4 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.0 0.8 0.0 0.7 0.0 3.3 0.5 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.3 0.2 0.2 0.1 0.0 0.1 0.1 0.0 4.0 5.4 2.0 5.8 5.8 3.0 2.4 2.9 1.4 2.0 2.6 3.4 0.2 0.0 1.3 920.7 0.2 0.1 0.0 0.0 0.0 3.0 0.1 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.1 18.3 0.0 0.1 0.5 0.1 0.6 0.7 0.0 0.0 519.3 0.2 0.0 0.5 0.0 0.4 1.3 0.0 0.0 0.0 0.1 1.7 723.8 3.8 0.0 0.0 0.3 0.0 0.6 0.3 1.8 39.4 0.0 2.4 0.0 108.0 30.3 0.0 3.4 1.5 0.0 0.4 0.0 0.4 0.0 1.3 0.0 1.1 0.6 0.0 1.7 0.0 0.0 0.0 0.1 0.1 7.4 0.1 B3GNT7 beta3GnT7 ENSG00000156966 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" Q8NFL0 2 231395710-231401164 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 272.8;Intestinal goblet cells: 145.2;Paneth cells: 126.4;Undifferentiated cells: 354.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 32.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 19.5;HEL: 15.6;THP-1: 14.0;WM-115: 23.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA013881, HPA035625, HPA035626" Enhanced Approved "Golgi apparatus,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 3600000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Mitotic spindle, Cytosol" "HPA013881: , HPA035625: AB_10601118, HPA035626: AB_2674707" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-3)" "unprognostic (1.46e-2)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "unprognostic (1.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.18e-2)" "unprognostic (5.82e-2)" "unprognostic (2.17e-2)" "unprognostic (7.77e-2)" "unprognostic (4.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.18e-1)" "prognostic favorable (6.00e-4)" "unprognostic (3.57e-1)" 3.1 12.9 5.9 2.8 5.1 14.2 3.8 4.0 5.8 2.5 4.6 56.2 25.2 1.9 6.8 2.9 4.6 14.0 4.7 5.6 6.5 2.2 1.2 15.3 1.6 6.0 7.0 16.7 25.4 14.3 8.8 5.4 5.3 3.2 71.2 2.1 7.5 4.4 0.4 5.0 28.4 2.3 4.3 5.1 35.6 1.3 7.3 2.4 8.4 0.3 1.5 3.7 0.6 5.4 0.7 2.8 0.3 0.6 0.1 0.2 1.0 0.2 1.1 0.1 0.1 1.4 19.5 2.2 5.8 0.3 0.2 5.1 0.2 0.0 0.1 0.3 0.5 15.6 0.5 0.9 0.1 0.1 0.8 0.1 1.4 0.2 0.3 1.1 0.2 0.4 0.5 0.4 0.1 0.9 0.2 0.7 6.3 7.7 3.3 0.3 0.1 0.4 0.6 1.7 0.5 0.8 0.3 1.7 0.7 6.9 0.6 14.0 0.2 0.4 0.4 0.2 0.2 2.3 0.9 0.7 0.3 0.2 23.7 0.7 0.1 0.7 2.9 0.5 0.5 9.9 0.1 0.4 6.5 7.0 0.1 0.7 0.2 32.1 0.6 3.1 0.2 1.0 5.9 5.1 4.0 5.8 5.6 6.5 6.0 7.0 5.3 4.3 7.3 5.4 0.9 41.7 30.2 0.3 8.7 2.3 1.7 8.7 0.0 0.4 5.2 2.5 1.1 95.8 29.7 1.8 2.1 0.6 61.7 272.8 0.0 16.1 0.4 13.3 2.2 4.7 103.0 0.4 0.5 84.3 64.9 2.3 51.5 18.5 9.5 17.3 3.3 0.2 11.2 0.0 0.4 145.2 18.3 10.1 38.6 1.2 1.5 9.7 3.6 0.0 2.9 0.5 10.3 55.3 0.2 69.8 126.4 8.2 5.5 11.6 93.2 0.4 82.2 1.8 0.0 0.5 2.3 0.9 1.4 0.0 2.7 2.1 10.0 0.4 354.6 16.2 BBOX1 "BBH, BBOX, G-BBH, gamma-BBH" ENSG00000129151 "Gamma-butyrobetaine hydroxylase 1" O75936 11 27040725-27127809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 467.9;liver: 131.9" "Cell type enriched" "Detected in many" 7 "Proximal tubular cells: 1623.0" "Group enriched" "Detected in many" 6 "glioma: 23.7;renal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTCEpi: 13.7;RPTEC TERT1: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007600, HPA027823" Enhanced Approved Uncertain "Vesicles,Actin filaments" NA NA 35000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Actin filaments" "HPA007600: AB_1845284, HPA027823: AB_10602394" "unprognostic (9.96e-3)" "unprognostic (1.80e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (7.03e-2)" "unprognostic (6.66e-2)" "unprognostic (7.05e-3)" "unprognostic (1.13e-2)" "unprognostic (3.03e-1)" "unprognostic (6.89e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.71e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-1)" "unprognostic (1.73e-3)" 1.4 0.0 24.3 0.0 23.4 0.0 25.1 28.8 34.0 5.1 17.3 0.2 0.0 0.1 8.1 17.5 9.0 9.6 0.0 22.8 25.6 467.9 131.9 0.3 0.1 27.2 33.1 0.0 0.8 0.0 6.9 0.3 35.0 0.5 0.0 0.4 6.1 4.1 0.9 51.8 0.0 0.0 28.8 0.0 0.2 0.1 25.2 1.1 9.6 0.0 0.6 0.1 11.3 27.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.9 13.7 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.2 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 23.4 28.8 34.0 22.8 25.6 27.2 33.1 35.0 28.8 25.2 27.0 0.1 0.0 0.6 66.3 5.3 8.2 9.0 80.9 0.6 0.0 16.3 11.0 0.0 15.7 18.1 46.0 0.0 0.3 0.2 0.0 223.0 0.7 1.1 10.3 0.1 0.3 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.9 0.0 0.1 0.4 27.9 0.0 0.0 0.8 0.0 12.2 0.6 1.1 1.1 0.0 7.1 1.8 4.7 0.0 13.8 0.0 2.0 0.3 0.1 0.0 0.4 0.0 0.2 0.0 1623.0 9.4 0.4 0.0 0.0 1.4 0.0 0.6 16.9 35.8 0.3 5.0 0.0 0.0 2.6 BCAP29 "BAP29, DKFZp686M2086" ENSG00000075790 "B cell receptor associated protein 29" Q9UHQ4 7 107580246-107629170 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029215, HPA049694" Supported Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA029215: AB_10602331, HPA049694: AB_2680854" "unprognostic (3.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.82e-2)" "unprognostic (1.05e-2)" "unprognostic (5.42e-3)" "unprognostic (4.71e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.43e-2)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (2.31e-2)" "unprognostic (7.36e-2)" "unprognostic (8.34e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-2)" "unprognostic (5.28e-3)" "unprognostic (1.81e-1)" 47.1 25.7 19.4 22.5 23.7 16.7 28.0 18.1 27.0 48.6 12.8 32.6 16.1 42.6 18.6 34.4 21.7 23.0 61.0 24.4 17.9 20.1 33.3 26.0 16.7 17.5 17.6 21.4 18.9 34.5 12.2 26.7 18.0 31.9 31.2 9.6 18.4 25.0 38.7 22.1 18.8 38.2 19.5 18.1 22.4 70.1 19.2 12.8 85.5 31.5 15.7 30.9 32.5 21.1 71.7 22.8 26.4 13.8 65.2 81.6 22.6 80.6 68.2 32.9 39.7 23.2 72.1 13.4 54.5 58.1 75.1 35.8 13.7 38.6 52.5 50.1 17.3 27.1 35.6 26.2 63.3 33.6 41.2 48.9 31.8 46.7 38.0 95.4 116.9 25.3 58.3 33.4 75.4 67.2 23.2 34.3 15.4 29.7 30.0 18.6 34.1 34.6 60.6 49.1 10.2 37.7 68.2 54.9 58.2 39.3 25.6 37.5 113.9 102.5 52.1 94.6 104.7 31.7 67.9 27.5 66.5 30.5 77.2 47.5 10.5 25.5 9.5 13.6 9.3 12.8 7.5 9.5 10.0 8.5 4.3 8.5 3.9 9.9 21.7 10.1 13.6 8.1 19.4 23.7 18.1 27.0 24.4 17.9 17.5 17.6 18.0 19.5 19.2 21.1 169.8 67.3 57.2 35.6 33.9 38.5 80.7 99.0 25.0 35.2 40.4 34.2 117.8 27.1 77.7 23.9 10.4 30.2 31.4 38.1 15.6 46.4 227.1 54.6 93.3 99.0 22.3 73.2 81.1 73.6 50.8 72.9 32.6 102.0 58.3 14.8 73.2 40.7 52.6 8.4 71.3 35.8 69.2 36.6 35.6 95.8 61.2 49.6 37.4 44.0 41.6 28.3 22.6 50.8 49.7 71.2 32.5 89.1 17.7 110.4 15.6 19.5 55.9 26.7 78.9 62.9 91.3 202.2 35.0 46.5 38.8 70.7 33.5 32.0 45.4 83.5 BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.8;Basal squamous epithelial cells: 73.4;Excitatory neurons: 57.5;Inhibitory neurons: 105.7;NK-cells: 51.5;Suprabasal keratinocytes: 71.3;T-cells: 133.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "JURKAT: 38.3;MOLT-4: 47.3" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" 0.4 0.3 8.0 5.1 21.2 4.9 1.1 0.0 17.2 0.9 0.0 1.2 2.0 0.2 0.5 4.3 0.3 0.9 0.1 18.9 1.1 0.3 0.4 1.1 10.2 0.3 0.8 0.2 0.1 0.0 0.2 0.1 0.0 0.5 1.4 0.0 1.7 0.3 0.2 15.0 3.5 0.2 1.5 4.4 1.9 0.5 2.0 36.6 0.8 0.0 7.5 1.3 2.9 3.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 1.7 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.2 0.0 0.0 38.3 0.0 4.1 0.0 2.8 47.3 0.8 0.5 3.6 0.0 7.0 0.0 0.0 0.0 2.6 3.7 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.7 0.2 0.0 2.6 0.1 0.0 2.0 0.7 0.0 0.0 0.0 0.1 2.0 0.0 1.8 0.0 2.8 2.4 0.0 0.0 4.6 3.1 0.0 0.3 0.0 0.0 2.0 0.8 8.0 21.2 0.0 17.2 18.9 1.1 0.3 0.8 0.0 1.5 2.0 3.9 1.3 3.2 0.0 1.3 6.4 62.8 1.6 6.3 73.4 0.4 4.3 4.4 3.8 4.3 1.3 0.0 0.0 0.1 44.2 3.8 1.9 0.2 0.2 0.2 0.2 1.2 1.2 5.3 57.5 0.5 0.0 3.3 2.0 0.3 5.1 0.2 3.3 0.3 0.3 0.0 105.7 4.9 2.0 1.0 11.4 0.4 0.6 4.0 5.4 1.0 4.9 0.0 51.5 32.2 2.0 1.1 5.4 0.0 24.4 0.6 10.1 0.5 0.3 0.1 0.0 0.5 1.9 1.6 5.8 42.7 71.3 0.0 133.4 0.1 9.7 0.6 BEND6 "bA203B9.1, C6orf65, FLJ30162" ENSG00000151917 "BEN domain containing 6" Q5SZJ8 6 56955107-57027346 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 30.9;retina: 11.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.6;Excitatory neurons: 87.3;Horizontal cells: 42.1;Inhibitory neurons: 118.6;Oligodendrocyte precursor cells: 49.8" "Cancer enriched" "Detected in many" 6 "glioma: 4.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 8.8" "Lineage enriched" "Detected in many" 6 "dendritic cells: 8.8" "Cell line enhanced" "Detected in many" "ASC TERT1: 28.8;fHDF/TERT166: 28.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031605, HPA052973" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA031605: AB_10602395, HPA052973: AB_2682002" "unprognostic (4.27e-1)" "unprognostic (7.05e-2)" "unprognostic (4.42e-2)" "unprognostic (1.18e-6)" "unprognostic (2.44e-1)" "unprognostic (2.10e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (9.41e-3)" "unprognostic (1.57e-1)" "unprognostic (8.82e-2)" "unprognostic (1.94e-2)" "unprognostic (9.84e-6)" "unprognostic (9.27e-3)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.98e-3)" 1.2 2.1 12.1 1.5 14.2 0.7 0.6 30.5 30.9 4.0 2.9 1.4 0.5 2.8 0.7 1.2 1.0 3.8 2.4 12.6 16.0 0.6 0.2 0.6 0.9 19.5 16.0 2.0 0.4 0.7 1.7 2.0 20.4 2.4 1.5 11.8 0.5 2.4 3.9 1.0 0.7 3.6 12.1 0.8 0.8 1.0 15.7 1.1 0.8 0.6 0.8 2.8 1.7 21.7 5.4 2.2 1.3 0.6 17.6 28.8 4.9 16.1 15.6 7.1 8.2 0.2 2.4 0.1 5.2 28.7 9.9 0.7 1.8 0.8 8.7 2.4 1.0 3.6 7.5 0.4 4.7 10.3 0.2 12.7 4.5 9.8 4.3 11.9 4.7 13.3 4.6 9.2 14.3 5.5 6.2 2.5 4.4 0.3 1.3 0.1 0.2 2.6 2.6 5.4 6.1 6.2 10.8 1.3 1.4 6.1 0.3 5.9 6.1 21.5 0.7 14.5 3.6 12.6 15.2 4.3 12.6 6.5 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 8.8 0.0 0.1 12.1 14.2 30.5 30.9 12.6 16.0 19.5 16.0 20.4 12.1 15.7 21.7 0.4 0.0 0.0 16.6 0.3 0.9 0.2 0.2 0.0 82.6 0.2 1.1 3.6 0.0 0.7 0.0 4.2 0.5 10.8 0.0 0.0 0.2 0.6 0.5 11.9 0.2 0.0 0.0 87.3 0.4 1.6 5.6 0.0 0.5 0.0 13.5 1.1 0.0 0.1 42.1 118.6 0.0 0.0 0.0 4.0 0.8 1.8 1.1 3.6 13.1 0.3 4.9 0.0 49.8 22.9 0.6 0.0 3.0 0.0 0.4 0.0 1.0 0.0 4.8 0.0 8.7 2.7 0.7 5.8 0.2 1.0 0.0 0.1 4.4 0.0 0.1 BEST3 "MGC13168, MGC40411, VMD2L3" ENSG00000127325 "Bestrophin 3" Q8N1M1 12 69643360-69699476 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 69.1;tongue: 55.8" "Cell type enhanced" "Detected in some" "Early spermatids: 10.3;Late spermatids: 17.9;Oligodendrocyte precursor cells: 70.4;Skeletal myocytes: 28.1" "Cancer enriched" "Detected in single" 9 "glioma: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "REH: 36.1;RPMI-8226: 38.4;U-698: 63.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA054582 Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" "HPA054582: AB_2682530" "unprognostic (1.53e-1)" "unprognostic (7.00e-2)" "unprognostic (9.83e-2)" "unprognostic (1.67e-2)" "unprognostic (5.15e-3)" "unprognostic (2.26e-3)" "unprognostic (7.30e-7)" "unprognostic (1.81e-1)" "unprognostic (1.74e-2)" "unprognostic (5.36e-2)" "unprognostic (1.19e-1)" "unprognostic (4.08e-2)" "unprognostic (4.82e-2)" "unprognostic (4.47e-2)" "unprognostic (3.03e-1)" 0.0 0.6 3.9 0.1 3.7 2.8 0.6 15.4 5.8 0.1 0.7 0.2 0.2 0.1 0.6 1.9 0.1 0.2 0.4 4.2 1.4 0.4 0.3 0.1 0.2 5.2 3.8 0.2 1.1 0.1 1.1 0.3 5.3 1.9 0.2 2.6 3.1 0.1 69.1 0.9 0.1 0.0 2.7 0.1 0.1 3.1 3.2 1.4 0.1 55.8 0.2 0.0 0.0 7.8 0.2 0.5 1.3 0.1 0.0 0.0 0.3 0.3 0.3 0.7 0.8 0.3 0.4 2.4 0.6 0.0 2.0 0.2 0.0 0.1 0.8 0.5 0.1 1.0 0.8 0.3 0.0 0.3 0.0 0.3 0.0 1.1 0.2 0.1 0.4 0.1 0.5 0.0 1.5 0.2 0.0 0.1 1.4 0.7 0.5 36.1 1.1 38.4 1.8 0.1 0.7 0.0 0.2 0.2 0.0 2.3 0.3 0.0 0.2 0.3 0.9 0.2 1.3 0.2 0.4 63.7 2.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 3.9 3.7 15.4 5.8 4.2 1.4 5.2 3.8 5.3 2.7 3.2 7.8 0.0 0.0 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 1.2 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 10.3 0.1 0.0 0.0 0.0 1.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 17.9 0.0 0.2 1.8 0.0 0.0 7.6 0.0 70.4 0.1 0.8 0.0 0.0 0.0 0.6 0.0 7.0 0.0 0.3 0.0 28.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 BEST4 VMD2L2 ENSG00000142959 "Bestrophin 4" Q8NFU0 1 44783585-44788170 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 16.4;fallopian tube: 8.3;intestine: 27.4" "Cell type enriched" "Detected in some" 25 "Paneth cells: 1290.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;U-698: 1.8" "Low region specificity" "Detected in many" HPA058564 Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA058564: AB_2683759" "unprognostic (5.76e-2)" "unprognostic (1.22e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-2)" "unprognostic (6.51e-3)" "unprognostic (1.09e-1)" "unprognostic (8.39e-2)" "unprognostic (1.45e-3)" "unprognostic (1.04e-1)" "unprognostic (8.97e-2)" "unprognostic (5.72e-2)" "unprognostic (1.29e-1)" "unprognostic (2.69e-5)" "unprognostic (1.43e-1)" "unprognostic (3.72e-1)" "unprognostic (1.28e-1)" "unprognostic (4.13e-3)" 0.2 1.9 1.2 0.7 1.1 0.7 0.5 2.2 1.3 1.6 16.4 27.4 9.1 0.7 3.0 0.2 8.3 0.2 0.3 0.8 1.7 0.5 0.6 1.9 0.6 1.9 3.3 0.5 0.3 0.3 2.7 0.2 1.5 0.4 16.0 1.1 0.3 0.5 0.4 2.2 8.1 0.5 1.3 0.5 0.4 0.7 1.6 0.5 0.6 0.1 0.4 0.3 0.2 1.0 0.0 0.2 0.3 0.4 0.1 0.1 1.1 0.2 0.1 0.1 0.0 0.1 0.5 0.1 0.5 0.1 0.3 0.5 0.1 0.0 0.1 0.3 0.2 0.0 0.8 2.5 0.1 0.0 0.3 0.2 0.3 0.1 0.2 0.6 0.3 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.8 0.3 0.1 0.1 0.1 0.2 0.4 0.0 0.5 0.1 0.1 0.1 0.2 0.4 0.1 1.8 0.4 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.6 0.8 0.6 0.7 0.0 0.5 0.2 0.5 0.1 0.3 0.0 0.3 0.6 0.1 1.2 1.1 2.2 1.3 0.8 1.7 1.9 3.3 1.5 1.3 1.6 1.0 0.2 0.0 0.0 0.0 0.8 0.3 0.8 3.4 0.0 0.8 0.4 1.0 0.5 0.0 4.2 5.5 0.0 0.3 0.4 31.2 1.9 0.7 0.0 26.7 0.5 0.2 2.4 0.0 1.9 0.8 0.2 0.6 0.5 1.2 0.0 0.3 0.4 0.0 0.3 0.0 4.3 3.2 0.0 0.0 0.9 0.2 0.9 0.2 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.6 1290.4 0.4 0.4 0.7 6.1 1.0 50.1 0.2 0.0 1.2 0.8 0.7 1.6 0.0 0.6 0.3 1.4 0.4 9.1 0.5 BGN "DSPG1, SLRR1A" ENSG00000182492 Biglycan P21810 X 153494980-153509546 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 795.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 223.5;Peritubular cells: 782.7;Sertoli cells: 1485.7;Smooth muscle cells: 401.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 312.6;BJ hTERT+: 400.8;fHDF/TERT166: 568.9;HSkMC: 283.9;hTEC/SVTERT24-B: 235.2;HUVEC TERT2: 561.2;U-138 MG: 249.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003157, CAB003678" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 3300000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Endoplasmic reticulum" "CAB003678: AB_425325, HPA003157: AB_1078282" "unprognostic (1.74e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-3)" "unprognostic (3.60e-1)" "unprognostic (5.42e-2)" "unprognostic (3.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.22e-2)" "unprognostic (1.76e-3)" "unprognostic (1.30e-2)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (6.00e-8)" "unprognostic (7.05e-3)" "unprognostic (2.40e-2)" "unprognostic (5.66e-2)" "unprognostic (2.57e-3)" 165.8 213.0 54.1 93.1 57.6 0.3 118.0 51.2 91.5 371.0 69.5 69.3 22.0 234.4 83.7 45.8 143.7 326.1 795.8 56.1 48.7 396.5 347.9 477.3 42.4 50.6 50.8 94.9 67.9 26.6 144.1 199.1 53.2 184.2 24.8 1.1 107.7 135.5 32.4 118.9 48.8 213.2 45.5 352.1 51.6 69.9 64.6 15.9 250.0 46.7 35.9 126.8 180.0 65.4 0.0 0.0 29.7 0.1 31.5 70.5 1.1 312.6 400.8 56.7 18.6 39.5 0.0 0.0 56.9 568.9 2.0 0.1 0.0 0.0 10.2 0.0 0.0 0.0 0.6 3.9 27.0 0.0 0.2 283.9 2.2 235.2 10.7 29.0 561.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 1.5 0.3 0.2 0.0 0.1 0.0 0.6 0.4 0.0 0.0 1.1 11.8 1.3 0.0 120.0 249.5 2.3 1.0 1.5 0.9 0.1 0.0 0.1 0.3 114.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 57.6 51.2 91.5 56.1 48.7 50.6 50.8 53.2 45.5 64.6 65.4 30.5 3.2 5.6 5.9 0.6 104.1 1.3 7.3 5.7 0.2 1.2 5.6 16.1 4.3 2.5 9.2 0.0 15.5 0.7 0.0 1.9 2.7 1.8 1.4 28.3 45.2 0.0 5.3 0.1 0.2 50.0 180.0 7.7 1.1 3.8 8.4 223.5 1.6 4.4 3.3 0.1 0.0 0.0 4.0 43.6 13.5 147.9 3.0 35.6 25.3 2.0 0.1 0.0 20.6 0.0 1.2 0.0 782.7 0.0 3.0 0.0 0.8 1.6 0.2 1485.7 3.1 401.3 0.8 1.2 1.8 54.1 56.9 3.0 7.7 0.0 1.6 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "BLM RecQ like helicase" P54132 15 90717346-90816166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 18.3;Oligodendrocyte precursor cells: 58.3;Plasma cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 0.3 0.2 0.9 3.6 1.1 5.7 0.5 2.3 0.9 0.1 0.3 1.4 1.0 0.4 0.4 0.6 0.3 0.3 0.3 0.8 1.1 0.1 0.1 0.4 6.4 1.2 1.4 0.1 0.2 0.0 0.6 1.2 1.1 0.1 1.7 2.4 7.8 0.0 0.5 0.4 1.6 0.4 1.0 1.6 1.1 2.2 0.9 7.9 0.3 0.1 6.2 1.0 0.2 1.0 13.0 14.4 20.4 12.6 0.1 0.9 14.6 9.4 3.2 11.1 13.4 11.7 10.1 35.1 5.9 2.6 14.1 20.4 25.7 7.1 15.1 19.1 20.5 36.4 14.8 3.9 0.0 33.7 17.3 0.3 0.1 10.6 4.7 1.3 7.9 16.9 32.7 9.9 11.0 7.4 28.3 14.5 22.2 24.9 4.2 25.4 39.1 14.7 2.3 18.9 14.6 14.7 8.5 11.5 4.8 18.1 7.2 23.4 3.7 8.6 13.6 9.6 21.0 6.4 30.4 39.5 5.6 25.8 15.7 1.7 0.6 2.6 1.6 0.8 2.6 4.6 1.4 2.1 0.7 2.3 1.0 1.1 0.7 3.1 1.0 0.7 3.2 0.9 0.9 1.1 2.3 0.9 0.8 1.1 1.2 1.4 1.1 1.0 0.9 1.0 0.9 3.2 8.9 1.0 12.9 0.3 0.5 0.5 0.6 3.6 1.3 1.0 7.9 0.0 4.2 0.0 2.1 5.5 6.9 2.2 1.9 1.0 2.7 1.3 1.3 2.0 0.0 18.3 0.7 0.7 6.8 1.8 3.6 1.7 13.3 8.1 2.2 0.6 5.7 0.0 8.6 1.3 0.0 7.7 1.3 1.6 0.0 7.7 0.0 7.5 2.7 1.7 10.3 58.3 2.6 1.2 0.3 0.4 20.6 0.7 0.2 0.0 5.4 7.1 0.0 0.9 1.7 17.1 12.9 2.2 0.6 1.0 10.2 0.7 4.0 0.4 BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 23.0;Hepatic stellate cells: 16.8;Inhibitory neurons: 22.8;Microglial cells: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 37.0;HUVEC TERT2: 149.6;Karpas-707: 81.6;SiHa: 70.0;TIME: 74.3;U-266/84: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" 16.5 3.1 5.1 2.2 5.9 0.4 12.7 3.9 6.2 3.2 7.8 3.7 3.0 3.5 0.6 2.0 2.4 2.1 5.1 3.9 3.7 17.8 1.9 9.1 1.5 4.9 4.5 8.2 0.6 0.6 4.6 18.1 4.7 2.8 2.7 0.1 2.3 2.6 3.1 3.5 3.0 2.3 4.8 4.6 4.7 2.2 5.7 0.9 1.5 1.3 2.4 3.3 3.0 4.1 0.9 2.4 0.3 0.0 0.4 0.3 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 37.0 1.1 1.6 0.5 1.1 0.2 0.0 0.0 5.7 15.9 21.8 1.4 0.8 1.1 16.7 0.0 0.0 0.7 2.4 9.6 149.6 0.0 0.0 81.6 0.0 0.3 0.0 0.0 0.8 0.5 12.0 0.6 0.0 15.3 0.5 0.0 12.3 0.0 70.0 0.0 0.0 9.3 0.0 0.0 74.3 0.0 4.7 0.5 2.6 11.3 41.3 0.1 2.3 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.1 5.9 3.9 6.2 3.9 3.7 4.9 4.5 4.7 4.8 5.7 4.1 23.0 0.0 0.5 1.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3.5 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.8 0.2 8.9 0.0 0.0 7.8 0.0 0.1 2.0 0.0 2.0 0.0 1.5 16.8 0.6 0.3 0.0 22.8 0.0 0.0 0.8 2.1 4.2 0.0 1.5 1.8 74.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.8 0.3 0.0 0.0 0.3 0.0 0.0 4.7 0.4 0.1 1.3 0.1 0.1 0.3 0.4 0.4 0.0 0.0 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "epididymis: 102.6" "Group enriched" "Detected in some" 4 "Endothelial cells: 28.2;Hepatic stellate cells: 93.9" "Cancer enhanced" "Detected in many" "melanoma: 3.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Cell line enriched" "Detected in some" 119 "HUVEC TERT2: 353.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 7.7 0.3 0.3 1.7 0.5 7.1 4.9 0.3 0.6 1.7 1.1 3.8 4.4 2.3 102.6 2.3 2.6 2.6 8.8 0.3 0.3 0.6 0.7 3.0 1.5 0.3 0.4 0.9 0.9 0.3 0.2 4.7 0.3 0.9 2.4 0.0 1.1 0.9 1.3 1.6 4.8 2.6 0.3 2.2 1.4 0.2 0.4 0.7 2.0 2.2 0.4 2.6 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 353.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.4 14.1 0.0 1.1 1.3 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.2 0.0 28.2 4.2 3.2 1.3 0.2 0.0 1.1 4.6 0.2 0.0 0.1 93.9 0.7 0.1 0.0 1.2 0.1 2.0 0.0 1.1 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.8 0.0 0.0 0.3 0.8 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.4 0.4 BNIPL "BNIP-S, BNIP-Salpha, BNIP-Sbeta, BNIPl-1, BNIPL-2, PP753" ENSG00000163141 "BCL2 interacting protein like" Q7Z465 1 151036321-151047720 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 128.5;skin 1: 181.4;vagina: 69.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 17.2;Squamous epithelial cells: 42.7;Suprabasal keratinocytes: 57.1;Urothelial cells: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "T-47d: 46.1" "Group enriched" "Detected in some" 9 "basal ganglia: 1.6;cerebellum: 2.4" "Not detected" "Not detected" HPA019946 Uncertain Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA019946: AB_2732424" "unprognostic (2.62e-1)" "unprognostic (7.59e-3)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.50e-4)" "unprognostic (6.58e-2)" "unprognostic (2.82e-2)" "unprognostic (3.32e-3)" "unprognostic (3.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-1)" "unprognostic (3.88e-4)" "unprognostic (1.91e-1)" "unprognostic (8.43e-11)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" "prognostic favorable (4.32e-4)" "unprognostic (6.81e-2)" 0.4 0.3 0.9 0.4 1.0 0.6 15.6 3.0 1.3 25.1 0.7 0.4 0.3 0.3 0.2 128.5 2.7 0.3 0.7 0.9 1.0 2.9 1.2 9.4 0.6 1.5 1.0 0.6 0.4 1.1 0.6 0.5 1.1 12.5 0.2 0.8 22.9 4.7 1.6 181.4 0.5 0.1 0.7 1.1 1.4 4.3 1.0 0.7 7.4 0.1 10.1 9.7 69.7 1.1 0.4 0.4 0.6 0.6 0.4 0.4 0.7 0.3 0.0 0.3 0.2 1.5 0.4 0.7 0.7 0.0 0.1 1.5 0.9 0.2 0.6 1.1 1.0 1.2 0.8 0.2 0.1 0.6 0.6 0.0 3.1 0.2 0.3 1.0 0.0 1.1 0.6 0.5 0.3 2.0 0.7 1.2 0.5 1.0 0.4 0.3 0.3 0.4 0.6 0.4 1.3 0.6 0.5 0.9 0.3 2.2 46.1 0.4 1.1 0.7 0.5 0.2 0.1 1.7 1.3 3.9 0.1 0.3 0.8 0.5 0.1 0.1 0.3 0.1 0.2 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.6 0.1 0.1 0.1 0.0 0.1 0.9 1.0 3.0 1.3 0.9 1.0 1.5 1.0 1.1 0.7 1.0 1.1 0.4 16.0 17.2 0.0 0.3 15.3 6.1 3.9 12.5 0.4 14.2 6.1 0.3 0.0 11.0 11.0 0.0 1.6 1.2 0.3 0.0 0.0 7.6 1.1 1.3 0.8 0.0 0.0 1.1 0.0 0.4 0.9 0.0 1.1 0.0 0.4 2.5 0.1 0.3 0.0 1.2 0.3 2.0 0.6 5.5 1.3 0.9 1.9 3.6 0.0 0.1 0.3 0.0 0.0 0.7 0.0 0.1 0.0 0.6 5.5 0.8 0.3 12.8 1.5 0.0 0.9 1.2 0.9 0.3 42.7 57.1 2.6 1.3 0.2 0.4 24.4 BOLA1 CGI-143 ENSG00000178096 "BolA family member 1" Q9Y3E2 1 149887890-149900798 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal tubular cells: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 49.3;MCF7: 52.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007005 Approved "Intracellular and membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA007005: AB_1078294" "unprognostic (5.73e-2)" "unprognostic (9.86e-3)" "unprognostic (8.84e-2)" "unprognostic (8.18e-2)" "unprognostic (9.33e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.67e-2)" "unprognostic (2.19e-1)" "prognostic favorable (6.41e-4)" "unprognostic (3.14e-3)" "unprognostic (3.36e-2)" "unprognostic (2.22e-1)" "unprognostic (8.73e-2)" "unprognostic (1.31e-1)" "unprognostic (9.58e-2)" "unprognostic (1.93e-3)" 14.9 21.2 8.6 5.8 9.3 3.9 16.1 9.7 17.9 16.1 7.3 24.0 15.3 17.2 0.9 15.7 15.6 3.7 20.5 8.4 8.2 23.0 26.4 10.0 7.0 9.3 8.0 14.5 19.7 5.5 14.4 2.6 8.4 16.8 1.7 1.1 19.3 7.2 23.2 22.5 15.9 2.0 9.2 16.2 20.3 9.9 9.3 5.3 15.8 5.0 1.4 19.0 13.8 10.8 16.4 21.3 2.0 4.2 1.2 4.1 4.0 6.7 1.7 5.0 4.1 15.2 22.0 2.1 16.6 2.8 2.3 17.9 0.0 3.5 0.2 22.8 8.2 1.1 6.1 2.4 7.7 0.0 16.8 3.8 7.3 1.5 0.5 2.0 6.0 49.3 9.1 5.4 2.7 52.9 21.1 5.3 1.3 14.7 6.1 16.4 1.2 4.4 2.3 2.1 13.5 14.8 8.8 14.5 15.9 1.7 26.9 4.5 2.5 6.4 10.5 14.6 0.2 29.5 23.3 0.2 9.0 5.1 6.8 8.6 9.4 12.4 14.8 8.1 15.3 16.2 13.5 11.5 9.9 14.6 18.8 18.1 4.6 9.1 5.2 19.2 18.8 9.3 8.6 9.3 9.7 17.9 8.4 8.2 9.3 8.0 8.4 9.2 9.3 10.8 11.9 3.2 9.5 5.5 10.0 4.5 16.3 19.0 10.8 7.3 23.9 30.5 21.1 34.3 11.2 23.9 4.2 20.2 6.3 12.8 68.4 24.6 8.8 12.1 13.6 13.7 12.6 27.1 2.4 19.8 25.3 16.4 19.4 10.4 5.1 13.9 20.7 40.9 17.0 10.1 3.3 22.8 18.3 12.5 3.5 3.5 15.8 6.6 5.4 1.0 10.3 23.5 19.6 2.5 7.5 15.7 17.6 20.7 18.0 23.1 41.5 57.4 14.2 12.3 39.5 10.9 15.7 22.6 16.2 18.4 6.7 14.0 10.1 22.8 21.2 10.0 BPNT1 ENSG00000162813 "3'(2'), 5'-bisphosphate nucleotidase 1" O95861 1 220057482-220090462 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 55.5;Proximal enterocytes: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 183.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048461 Approved Approved "Nuclear speckles" NA NA 420000 "Cluster 44: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "Nuclear speckles" "HPA048461: AB_2680404" "unprognostic (6.42e-2)" "unprognostic (4.69e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (5.19e-3)" "unprognostic (7.65e-2)" "unprognostic (2.07e-2)" "unprognostic (3.00e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (6.69e-2)" "unprognostic (2.87e-1)" "prognostic favorable (6.38e-4)" "unprognostic (1.82e-2)" "unprognostic (6.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" 16.2 20.8 6.5 18.2 7.8 4.6 20.3 7.5 9.1 18.1 7.3 37.7 43.9 13.9 13.0 14.7 17.6 21.2 17.7 7.3 6.8 31.5 25.0 17.6 34.2 7.6 6.8 17.9 7.7 21.5 10.9 13.2 7.1 13.8 32.2 15.5 17.3 11.9 9.3 10.3 45.7 18.3 7.5 14.6 19.7 14.8 6.7 17.7 20.8 11.3 44.3 15.8 9.9 10.0 37.5 30.3 22.1 17.5 40.6 33.3 35.4 48.0 25.0 42.9 38.3 40.1 70.7 183.9 64.8 33.2 19.1 26.1 45.8 42.3 34.5 68.8 51.2 33.3 34.6 48.3 23.8 90.4 29.9 31.8 20.7 61.0 25.3 28.0 35.9 54.1 62.3 18.4 43.4 21.2 51.9 24.3 18.9 32.0 37.1 36.5 62.9 54.0 55.5 49.2 40.2 33.6 60.1 71.5 43.0 22.1 56.5 31.7 54.2 25.4 19.5 36.7 60.8 31.3 81.6 85.0 22.0 33.6 56.8 20.6 9.2 6.1 12.3 10.0 9.4 20.8 12.8 12.7 10.9 16.5 15.0 11.2 1.1 14.0 9.9 13.3 14.6 9.7 6.5 7.8 7.5 9.1 7.3 6.8 7.6 6.8 7.1 7.5 6.7 10.0 9.3 28.9 23.9 3.6 12.7 3.3 12.5 22.0 3.4 13.7 9.1 6.2 10.5 11.5 23.4 14.7 10.4 13.1 11.6 55.5 13.7 18.7 2.5 10.3 7.7 7.7 19.2 5.5 8.4 15.6 14.1 7.8 7.7 9.7 3.8 12.1 7.9 12.6 9.8 6.7 10.8 14.5 32.6 7.5 3.6 3.1 9.6 7.2 10.6 1.9 8.0 10.8 15.5 10.1 13.0 18.9 28.5 13.5 10.3 6.3 56.9 29.5 14.5 12.0 13.1 5.6 8.7 15.5 11.8 8.2 5.1 25.2 9.6 25.0 17.2 12.7 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 115.4;Spermatogonia: 85.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.0 1.3 0.0 5.8 0.5 0.0 0.0 0.2 0.2 0.7 0.5 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.3 0.3 2.1 0.1 0.1 0.1 0.1 0.0 0.0 1.0 0.1 0.1 0.8 0.0 0.2 0.0 0.0 0.7 0.5 0.3 0.1 0.9 0.6 2.7 0.2 3.1 0.2 0.0 2.0 0.5 0.2 0.1 4.7 4.0 6.0 5.0 0.6 1.4 7.0 4.8 3.1 5.5 5.0 10.6 6.0 15.9 3.2 2.1 7.6 6.1 5.5 2.9 10.5 10.5 3.1 10.3 2.5 3.5 0.1 15.4 4.9 0.2 0.0 10.3 6.9 0.4 4.5 8.1 7.0 5.5 6.4 5.1 11.8 8.3 8.3 4.9 2.3 11.4 17.3 3.0 1.4 5.4 2.4 4.6 5.9 2.4 2.2 2.2 2.9 7.3 1.3 6.3 6.8 7.0 6.7 2.0 3.3 8.0 2.7 5.7 5.8 0.0 0.3 1.5 0.5 0.7 0.1 1.7 0.4 0.4 0.3 2.2 0.5 0.4 0.8 0.5 0.8 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 4.4 9.6 2.6 0.0 12.4 2.5 3.3 2.5 2.2 0.0 4.3 3.3 1.9 0.0 1.8 0.0 0.0 14.1 10.5 4.8 0.0 2.5 5.2 4.4 6.3 5.5 1.2 29.5 0.7 1.6 12.7 5.8 10.7 4.6 3.8 26.9 1.4 0.8 9.5 0.0 0.5 4.4 0.0 7.5 11.0 4.4 2.1 14.4 3.6 4.7 20.1 0.3 0.0 0.0 0.6 1.2 1.8 1.2 27.8 1.2 1.0 0.6 2.9 0.0 13.1 8.3 5.3 115.4 85.6 8.0 1.3 5.5 7.9 4.2 7.8 2.3 BRD1 "BRL, BRPF2" ENSG00000100425 "Bromodomain containing 1" O95696 22 49773283-49827512 "Predicted intracellular proteins" "Erythrocyte maturation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000807, HPA001063" Enhanced Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA000807: AB_1078298, HPA001063: AB_1078297" "unprognostic (1.96e-1)" "unprognostic (2.99e-2)" "unprognostic (1.07e-1)" "unprognostic (5.11e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "unprognostic (2.18e-2)" "unprognostic (9.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.28e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-3)" "unprognostic (5.87e-2)" "unprognostic (7.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.26e-1)" "unprognostic (3.95e-3)" 11.4 7.3 3.1 8.1 3.0 15.0 10.8 12.0 5.0 12.5 3.6 14.7 11.7 15.8 2.8 12.8 13.7 7.7 7.5 3.4 3.2 5.4 6.9 10.0 9.4 3.2 2.8 16.0 13.2 8.5 11.2 8.3 2.9 8.7 5.8 6.1 12.1 8.0 16.7 23.2 12.0 6.7 1.5 12.0 11.5 30.7 3.2 14.0 10.2 8.9 7.6 11.8 12.3 4.5 12.7 12.7 22.8 12.8 9.2 8.2 19.3 13.7 9.3 14.2 11.1 19.3 8.3 13.3 7.9 11.4 5.2 17.9 14.7 9.8 6.1 13.4 26.6 13.2 20.3 11.8 17.8 30.5 18.2 12.2 15.1 8.3 10.5 10.3 10.4 15.9 15.3 14.3 7.3 20.8 23.0 15.9 15.7 9.4 10.1 33.6 19.9 13.9 5.5 18.2 14.6 25.8 17.6 22.7 18.4 10.5 10.6 24.9 12.9 13.1 14.1 9.9 12.7 16.8 4.3 18.9 9.3 10.7 11.8 0.3 0.6 0.7 0.5 0.2 1.0 0.4 0.8 1.0 0.4 0.7 0.8 1.0 0.6 0.8 2.9 0.9 0.3 0.5 3.1 3.0 12.0 5.0 3.4 3.2 3.2 2.8 2.9 1.5 3.2 4.5 25.9 22.4 27.6 16.3 13.8 15.8 5.7 7.1 8.6 26.6 14.0 14.7 8.4 5.7 12.7 3.7 29.2 6.7 76.8 13.3 0.0 6.7 7.5 32.4 37.1 13.9 16.2 8.2 25.3 9.3 6.6 17.2 14.8 47.7 10.1 28.3 14.3 12.3 6.7 33.7 22.2 13.9 4.1 13.3 14.0 6.7 11.8 15.4 12.4 16.9 11.2 13.8 7.2 19.1 21.9 9.5 8.7 13.9 43.1 9.1 10.6 3.2 11.3 36.1 0.0 25.4 20.1 42.6 19.7 10.7 18.5 10.1 40.6 26.4 11.3 9.0 BSPRY FLJ20150 ENSG00000119411 "B-box and SPRY domain containing" Q5W0U4 9 113349541-113371233 "Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 447.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 61.9;Ductal cells: 66.8;Exocrine glandular cells: 65.8;Pancreatic endocrine cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 21 "dendritic cells: 4.4" "Cell line enhanced" "Detected in many" "A-431: 41.8;CAPAN-2: 25.9;MCF7: 62.0;OE19: 70.9;RPMI-8226: 32.3;SK-BR-3: 29.9;T-47d: 30.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 3.8" "HPA042889, HPA077485" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm Cytosol "HPA042889: AB_10795515, HPA077485: " "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "unprognostic (1.18e-1)" "unprognostic (2.20e-3)" "unprognostic (1.68e-1)" "unprognostic (2.10e-3)" "unprognostic (4.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (2.28e-1)" "unprognostic (1.95e-2)" "prognostic favorable (4.56e-14)" "unprognostic (1.15e-3)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.70e-1)" 0.3 3.1 3.7 2.6 11.3 5.9 14.6 5.9 4.2 6.5 1.2 12.0 8.8 1.1 10.9 30.1 4.4 4.4 1.5 2.5 3.0 14.4 0.8 5.6 0.8 2.1 4.8 0.0 41.7 447.2 8.3 1.7 1.7 5.0 11.0 6.9 81.6 4.5 0.0 26.3 7.0 0.7 1.7 0.5 24.7 2.8 5.9 1.8 30.3 0.1 3.1 3.0 7.6 2.5 41.8 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 8.6 25.9 0.0 0.4 0.0 0.0 3.6 0.4 0.0 0.0 4.6 3.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.8 0.3 0.0 0.0 62.0 0.7 0.0 1.0 70.9 0.0 0.9 0.0 32.3 4.0 8.8 13.7 0.0 0.0 29.9 0.0 1.7 30.3 4.3 0.0 0.0 0.0 0.1 0.0 9.7 13.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.4 0.0 0.0 3.7 11.3 5.9 4.2 2.5 3.0 2.1 4.8 1.7 1.7 5.9 2.5 0.3 6.4 6.9 0.0 2.5 1.0 2.0 4.4 0.0 1.8 61.9 31.2 2.8 17.2 9.5 27.6 6.2 9.2 9.9 20.8 39.2 66.8 0.5 11.3 1.6 0.9 20.4 15.6 1.0 65.8 1.1 0.7 21.4 17.3 3.8 1.5 0.0 0.8 1.4 0.0 3.2 19.1 12.2 0.3 0.3 0.6 0.0 0.5 10.6 0.0 1.0 0.8 3.1 0.5 0.2 48.6 14.5 0.0 2.5 13.8 13.5 21.2 9.7 12.1 0.0 0.0 1.7 0.6 4.3 26.4 14.2 6.7 1.3 0.1 24.9 17.7 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.8;Macrophages: 33.3;monocytes: 80.1;Proximal enterocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Cell line enhanced" "Detected in many" "THP-1: 76.0;TIME: 40.4;U-937: 52.5;WM-115: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 21.2 2.7 1.9 13.7 2.1 139.8 9.4 2.1 4.7 11.0 1.6 8.3 48.6 6.3 2.9 4.6 7.9 18.2 19.1 2.1 2.0 17.0 8.5 12.7 7.1 1.9 1.4 9.3 3.1 1.7 1.3 13.7 2.2 3.7 9.7 1.0 3.9 4.6 2.7 5.0 29.3 9.7 0.8 18.6 3.2 2.7 3.0 3.9 4.9 6.8 3.5 16.8 7.4 3.3 0.6 10.5 1.2 1.0 28.8 7.0 1.6 21.0 2.1 20.4 22.2 0.3 12.1 0.8 1.9 12.2 0.6 0.3 3.3 0.5 17.2 0.8 0.7 5.6 0.8 0.6 6.7 7.2 15.1 5.7 1.5 12.9 1.0 0.9 3.0 5.0 0.7 0.5 12.5 0.3 2.3 4.3 2.7 0.9 2.2 0.8 1.8 0.5 0.5 0.6 1.4 4.3 0.4 0.7 14.2 1.2 0.5 76.0 40.4 0.6 1.0 7.9 1.1 0.6 0.2 0.7 2.7 52.5 44.8 41.8 257.7 20.8 1.1 97.4 1.7 2.2 0.9 0.8 78.9 0.9 1.1 0.7 292.7 0.4 73.9 26.6 1.0 109.8 1.9 2.1 2.1 4.7 2.1 2.0 1.9 1.4 2.2 0.8 3.0 3.3 5.4 3.2 3.7 1.3 0.3 4.6 0.8 0.1 1.8 0.6 1.2 2.0 1.5 2.8 1.0 1.8 0.0 16.0 5.5 3.7 1.9 4.4 4.4 8.0 9.9 3.8 1.2 2.5 0.7 2.5 24.0 22.5 0.0 16.2 15.9 20.6 6.4 2.1 40.8 0.0 0.7 8.1 0.0 26.3 11.5 1.2 3.1 33.3 14.2 3.7 80.1 0.6 3.1 0.5 3.6 1.1 11.9 2.2 0.4 0.6 79.0 9.6 3.0 0.2 6.6 3.9 15.5 2.5 1.4 1.7 3.0 7.1 1.8 1.4 23.2 3.3 BTG1 APRO2 ENSG00000133639 "BTG anti-proliferation factor 1" P62324 12 92140278-92145846 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2751.6;Langerhans cells: 2893.3;Suprabasal keratinocytes: 3004.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 33.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005972 Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA005972: AB_1078303" "prognostic favorable (4.36e-5)" "unprognostic (1.43e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-3)" "unprognostic (1.10e-1)" "unprognostic (5.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (2.50e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.95e-7)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (5.79e-2)" "unprognostic (9.81e-2)" 91.5 36.9 1.9 19.8 2.0 93.9 80.1 33.5 4.1 62.3 1.4 38.9 8.5 45.6 1.5 29.5 55.9 7.1 45.2 2.5 4.6 52.4 69.7 55.5 23.8 3.6 2.6 45.6 63.7 8.3 26.2 6.2 3.7 40.5 4.8 5.2 30.5 4.5 20.5 120.6 58.4 8.2 3.5 92.2 39.3 12.4 3.1 20.1 21.9 3.7 18.2 38.5 60.1 3.0 5.7 5.4 3.5 0.9 13.4 16.9 3.2 8.0 6.3 2.3 2.3 2.4 1.6 5.7 1.5 3.3 3.5 3.9 1.6 3.0 2.2 9.8 8.8 0.8 2.9 1.3 15.0 3.7 1.9 14.1 11.9 4.5 11.7 8.5 5.0 2.4 4.6 7.1 3.4 3.7 5.5 9.4 2.2 3.0 11.0 15.2 2.4 1.5 5.5 6.5 3.4 7.8 6.1 4.4 17.3 2.1 21.5 7.7 2.6 3.9 1.3 3.6 3.7 14.0 6.3 8.9 3.1 2.4 4.6 36.2 21.8 151.8 22.8 16.2 27.8 92.4 47.3 40.7 9.2 105.5 133.1 53.6 75.9 68.8 22.8 8.0 66.8 51.3 1.9 2.0 33.5 4.1 2.5 4.6 3.6 2.6 3.7 3.5 3.1 3.0 1186.6 96.1 185.4 12.1 2512.8 2751.6 1030.9 206.6 912.9 592.7 607.5 573.8 119.5 1009.4 140.4 174.7 196.0 412.8 1907.2 672.9 320.8 388.1 411.8 216.7 258.8 709.0 452.4 230.7 7.9 255.8 416.3 529.1 406.7 264.7 286.6 197.4 339.1 274.9 361.4 424.0 20.6 373.8 193.3 564.3 2893.3 213.7 287.1 1251.4 983.6 31.9 1241.2 877.6 1354.3 22.1 8.4 364.4 668.7 241.9 758.5 791.3 667.9 162.6 53.0 377.2 539.0 870.7 723.5 130.1 101.5 508.7 3004.2 1342.7 2354.0 786.4 410.9 1513.3 C10orf90 "bA422P15.2, FATS, FLJ32938" ENSG00000154493 "Chromosome 10 open reading frame 90" Q96M02 10 126424997-126798708 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 112.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 819.4" "Cancer enriched" "Detected in some" 5 "melanoma: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SK-MEL-30: 118.8;U-2197: 36.1;U-266/84: 27.2;U-87 MG: 37.0;WM-115: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038648, HPA075229" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA038648: AB_10672721, HPA075229: " "unprognostic (1.21e-2)" "unprognostic (3.34e-1)" "unprognostic (7.50e-2)" "unprognostic (2.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.30e-2)" "unprognostic (1.98e-3)" "unprognostic (5.06e-2)" "unprognostic (9.34e-3)" "unprognostic (3.73e-2)" "unprognostic (9.52e-2)" "unprognostic (1.22e-1)" "unprognostic (5.06e-11)" "unprognostic (2.69e-3)" "unprognostic (9.91e-3)" "unprognostic (1.26e-1)" "unprognostic (2.88e-1)" 0.7 0.0 30.4 0.1 74.4 0.0 4.7 41.9 47.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 29.9 37.4 0.3 0.1 0.0 0.0 60.4 53.8 0.1 0.2 0.0 0.3 0.3 57.0 0.0 0.1 0.0 10.6 0.0 0.1 1.1 0.1 0.0 29.8 0.0 0.0 6.5 68.0 1.1 0.3 0.4 0.7 0.0 0.0 112.1 0.3 0.1 0.0 0.0 0.8 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 2.3 0.0 1.6 0.0 0.9 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 2.6 0.0 0.0 0.0 0.0 118.8 0.0 0.0 0.2 0.0 4.7 0.0 36.1 0.7 0.0 27.2 0.0 37.0 0.0 29.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.4 74.4 41.9 47.7 29.9 37.4 60.4 53.8 57.0 29.8 68.0 112.1 0.2 0.0 0.0 24.5 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 120.5 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.0 142.7 0.3 0.0 0.0 3.7 0.0 0.0 0.0 181.0 819.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 1.3 0.5 0.0 0.0 4.2 0.1 0.0 0.0 0.0 C10orf95 FLJ14280 ENSG00000120055 "Chromosome 10 open reading frame 95" 10 102449837-102451543 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 9.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 30.1;Rod photoreceptor cells: 18.4;Syncytiotrophoblasts: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 11.8;JURKAT: 11.7" "Low region specificity" "Detected in single" "Secreted - unknown location" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.31e-1)" "unprognostic (7.76e-3)" "unprognostic (3.19e-1)" "unprognostic (5.62e-3)" "unprognostic (4.02e-1)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (5.98e-2)" "unprognostic (1.50e-2)" "unprognostic (1.01e-1)" "unprognostic (4.42e-2)" "unprognostic (2.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (2.14e-1)" "unprognostic (1.22e-2)" "unprognostic (4.80e-3)" 0.5 1.5 0.7 1.8 0.6 2.0 0.2 2.8 1.1 1.1 0.9 1.2 2.5 1.2 0.4 1.3 9.7 1.4 0.6 0.6 0.8 1.4 0.4 3.5 2.9 0.3 0.2 1.1 4.7 0.1 1.3 0.7 0.1 1.6 0.4 4.7 4.0 0.1 0.7 4.1 2.3 0.0 0.0 2.6 3.6 0.7 0.9 0.0 5.3 0.0 0.5 0.6 0.5 0.1 5.7 1.1 0.1 2.3 0.0 0.0 4.9 0.2 0.0 0.0 0.0 4.4 9.8 5.0 2.2 0.0 0.7 9.8 0.0 0.4 0.0 4.3 11.8 3.2 4.7 3.7 0.0 4.4 3.0 0.1 1.8 0.0 0.1 3.1 0.0 11.7 5.6 4.1 0.0 4.5 2.4 4.2 2.2 2.0 3.3 7.0 0.1 5.4 1.1 2.0 8.8 1.3 2.4 1.5 3.1 1.7 4.8 0.3 0.4 0.2 1.0 0.2 0.5 3.5 2.9 3.3 0.2 6.5 0.1 2.1 1.2 1.7 7.8 0.6 7.4 10.7 8.4 7.9 3.6 8.3 11.7 9.9 0.9 10.1 0.3 6.3 9.6 4.9 0.7 0.6 2.8 1.1 0.6 0.8 0.3 0.2 0.1 0.0 0.9 0.1 0.3 0.0 3.2 0.7 3.1 1.5 4.3 0.5 0.0 4.6 2.4 2.5 0.1 2.8 4.2 5.5 10.4 2.3 6.4 2.5 3.9 1.5 0.1 30.1 0.7 1.0 1.2 1.3 0.7 1.1 1.7 0.3 1.5 4.0 0.0 0.8 0.4 0.3 2.3 3.3 0.7 3.7 4.1 1.0 1.0 0.5 0.6 1.4 0.0 0.0 2.2 2.7 6.2 0.0 0.0 0.7 0.4 0.7 2.5 3.3 2.0 4.2 8.7 18.4 0.0 0.9 0.5 0.7 1.4 1.9 1.6 38.0 3.2 0.7 3.2 2.9 C11orf24 DM4E3 ENSG00000171067 "Chromosome 11 open reading frame 24" Q96F05 11 68261338-68272001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 107.7;Proximal enterocytes: 162.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 222.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012411, HPA012748" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012411: , HPA012748: AB_1845526" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (1.19e-1)" "unprognostic (8.22e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.31e-2)" "unprognostic (7.91e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.56e-1)" "unprognostic (2.68e-2)" "unprognostic (4.99e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.60e-9)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (8.67e-3)" 25.0 17.6 8.9 20.7 12.2 4.7 21.0 12.1 12.7 23.3 8.2 29.2 53.8 39.2 7.3 15.5 22.2 17.6 31.5 9.7 10.5 17.0 87.4 24.1 15.5 14.4 11.6 19.3 27.3 7.3 14.5 16.1 12.5 22.9 17.4 3.0 34.0 17.6 13.7 15.4 59.4 32.6 11.0 20.8 23.6 14.6 12.8 6.4 17.0 15.2 16.7 22.3 19.4 15.2 44.8 45.5 26.4 51.6 62.1 62.5 29.7 105.4 67.5 51.8 53.1 96.2 26.9 20.1 31.7 131.3 47.2 49.4 39.1 47.4 33.2 22.1 23.1 21.4 44.8 65.3 50.1 18.3 68.7 52.1 34.6 78.8 32.0 31.0 21.2 10.6 37.9 32.2 44.6 55.7 4.5 26.4 44.2 72.1 53.8 8.2 44.8 104.1 23.9 21.1 17.3 31.8 33.3 27.1 222.8 21.8 25.6 15.3 23.3 80.8 50.2 103.3 47.3 39.4 41.4 18.8 65.1 14.1 79.9 16.7 12.1 12.6 14.0 19.0 9.4 26.7 7.9 8.9 19.5 35.7 7.3 7.7 1.8 9.9 14.1 26.7 8.4 12.6 8.9 12.2 12.1 12.7 9.7 10.5 14.4 11.6 12.5 11.0 12.8 15.2 6.8 9.6 3.6 3.3 25.5 14.0 12.2 11.7 9.6 4.8 8.2 8.9 10.4 11.5 6.9 9.2 2.1 11.9 12.4 36.2 1.9 21.9 3.5 5.3 17.8 6.6 4.8 9.1 4.1 31.5 30.7 21.1 18.3 6.8 45.0 5.0 9.3 107.7 15.8 0.0 4.2 50.0 6.1 12.9 23.5 7.1 14.0 12.3 28.4 5.6 14.9 6.8 18.6 6.6 8.5 26.9 16.6 16.1 67.0 13.0 162.5 10.6 9.4 2.9 13.1 11.2 20.2 20.7 27.1 9.6 11.2 10.5 6.5 9.6 15.5 10.6 C12orf75 "AGD3, OCC-1, OCC1" ENSG00000235162 "Chromosome 12 open reading frame 75" Q8TAD7 12 105235290-105396097 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 109.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 841.2;Ductal cells: 626.3;Endometrial ciliated cells: 579.1;Extravillous trophoblasts: 1228.2;Proximal tubular cells: 762.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 661.2" "Group enriched" "Detected in all" 6 "dendritic cells: 661.2;T-cells: 169.9" "Cell line enhanced" "Detected in all" "BJ: 877.8;BJ hTERT+: 517.0;fHDF/TERT166: 432.7;RPTEC TERT1: 425.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065311 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA065311: AB_2685463" "unprognostic (5.96e-2)" "unprognostic (3.85e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (6.73e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (8.61e-2)" "unprognostic (1.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.33e-1)" "unprognostic (7.00e-2)" "prognostic favorable (1.69e-5)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.00e-1)" "unprognostic (4.47e-3)" 12.2 7.3 4.3 8.9 4.7 11.3 11.6 9.4 7.2 31.3 2.1 24.9 9.2 18.5 6.1 8.7 20.9 38.2 2.5 4.1 8.8 58.5 2.0 7.5 14.7 5.3 5.5 6.6 33.8 20.1 3.5 9.3 4.9 41.2 22.0 2.8 4.2 109.3 32.0 9.5 8.8 6.7 6.5 6.3 49.9 26.6 8.8 10.8 2.9 11.8 19.1 5.0 27.0 5.4 43.6 66.6 16.5 14.9 61.2 117.3 30.3 877.8 517.0 194.2 109.4 133.2 3.6 12.2 348.9 432.7 31.7 70.4 36.6 50.3 212.9 241.1 65.0 38.8 17.7 26.5 7.7 29.8 37.7 49.6 12.0 66.4 73.8 113.0 26.1 69.9 1.9 58.8 192.4 14.4 115.3 262.5 39.6 15.8 153.3 21.6 44.3 11.2 425.3 4.3 73.5 18.4 36.9 7.7 16.2 45.2 22.6 7.1 44.2 201.7 77.2 77.0 118.1 34.9 57.6 58.8 44.5 9.7 55.3 39.0 0.7 1.2 165.5 0.5 80.4 19.7 69.2 169.9 23.3 16.2 19.8 102.4 3.5 69.4 1.6 661.2 144.1 88.3 4.3 4.7 9.4 7.2 4.1 8.8 5.3 5.5 4.9 6.5 8.8 5.4 12.8 3.2 2.8 1.6 61.2 100.2 65.9 21.9 38.7 4.5 32.2 26.9 1.1 271.7 20.9 187.6 4.2 35.3 519.5 469.8 841.2 626.3 152.3 579.1 32.6 14.8 333.2 15.8 2.7 222.3 1228.2 53.0 160.5 293.1 2.5 9.7 13.2 1.8 31.9 63.9 2.9 63.6 85.5 5.3 97.3 324.1 15.5 48.2 60.5 40.3 29.1 6.4 299.7 0.5 0.4 420.0 175.5 4.9 160.3 87.0 102.1 762.3 129.7 4.9 6.6 8.6 127.8 102.9 118.6 37.1 61.2 40.6 143.0 0.7 63.9 37.3 C1orf112 FLJ10706 ENSG00000000460 "Chromosome 1 open reading frame 112" Q9NSG2 1 169662007-169854080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 13.5" "Cell type enhanced" "Detected in many" "Microglial cells: 30.0;Spermatocytes: 37.1;Spermatogonia: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023778, HPA024451" Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA023778: AB_1848665, HPA024451: AB_1848667" "unprognostic (4.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (9.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.40e-2)" "unprognostic (2.50e-3)" "unprognostic (2.09e-1)" "unprognostic (9.11e-3)" "unprognostic (8.79e-2)" "unprognostic (3.47e-3)" "unprognostic (5.97e-2)" "unprognostic (1.65e-8)" "unprognostic (1.76e-1)" "unprognostic (2.81e-2)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" 1.8 1.2 0.6 3.3 0.9 9.0 2.9 1.7 0.8 2.3 0.5 2.6 1.2 2.9 1.0 2.0 1.5 1.4 1.0 0.5 0.4 1.1 2.6 1.7 6.3 1.0 0.6 2.2 1.5 13.5 1.0 3.4 0.8 1.8 4.1 5.4 1.5 2.0 0.9 2.4 1.8 2.7 0.7 2.8 1.9 10.3 0.9 11.6 1.7 1.5 7.9 3.1 1.7 1.5 32.7 17.5 21.9 11.3 3.5 4.8 32.2 21.1 10.7 30.0 30.6 19.1 27.7 29.0 9.3 7.0 10.7 26.0 27.6 14.7 34.3 16.9 16.5 27.1 23.0 14.1 1.2 35.8 11.3 1.5 1.9 22.5 5.3 3.5 12.8 16.8 44.9 48.0 24.8 7.9 31.5 10.3 28.8 22.9 12.1 23.3 24.7 19.5 4.0 16.1 16.2 16.9 13.4 22.1 6.9 20.6 21.0 18.3 9.5 24.1 19.1 17.8 28.9 12.9 20.9 30.6 9.0 26.4 24.1 2.2 0.8 1.0 0.6 1.9 0.4 1.4 0.6 0.6 1.2 1.4 0.3 0.5 0.1 2.1 2.3 0.4 0.7 0.6 0.6 0.9 1.7 0.8 0.5 0.4 1.0 0.6 0.8 0.7 0.9 1.5 1.2 0.0 3.3 4.2 4.0 1.8 2.7 2.6 1.2 4.1 1.7 1.8 0.5 0.0 1.5 0.0 6.2 9.1 1.6 1.9 0.0 2.7 8.7 0.9 2.1 2.2 0.0 3.4 9.9 3.4 9.1 2.5 2.6 1.2 4.5 9.8 2.9 3.8 6.2 1.7 9.6 1.2 6.1 3.5 2.1 4.1 2.1 3.0 3.6 30.0 1.3 2.4 0.0 13.0 13.2 3.0 0.3 3.8 5.5 1.0 0.8 0.7 2.0 6.6 6.6 1.4 2.6 37.1 20.3 2.8 1.0 3.8 3.3 2.2 2.6 2.4 C1orf115 "FLJ14146, RDD1" ENSG00000162817 "Chromosome 1 open reading frame 115" Q9H7X2 1 220690363-220699153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 120.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 109.8;Hepatocytes: 121.3;Proximal enterocytes: 255.7;Syncytiotrophoblasts: 183.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 62.4;HUVEC TERT2: 49.7;TIME: 93.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (5.16e-2)" "prognostic favorable (6.52e-4)" "unprognostic (1.31e-1)" "unprognostic (3.93e-2)" "unprognostic (2.03e-1)" "unprognostic (5.69e-3)" "unprognostic (8.65e-2)" "prognostic favorable (5.12e-5)" "unprognostic (3.11e-1)" "unprognostic (1.33e-1)" "unprognostic (1.74e-2)" "unprognostic (4.24e-1)" "unprognostic (4.54e-2)" "unprognostic (9.21e-3)" "unprognostic (1.07e-1)" 50.0 6.8 32.3 6.8 43.4 0.3 28.4 10.8 45.8 14.8 17.3 30.9 112.4 12.5 21.3 5.7 14.4 10.3 18.9 47.5 11.5 52.8 101.4 23.4 8.5 13.1 10.5 17.9 12.1 20.5 17.5 70.2 13.5 31.1 23.3 8.9 74.1 10.6 14.6 9.1 120.9 11.8 10.0 50.0 22.4 7.2 15.9 3.8 16.5 19.3 9.5 6.9 7.2 25.9 1.6 7.3 0.5 10.1 0.0 0.0 29.0 2.0 8.1 4.2 18.3 7.3 7.6 0.0 3.1 0.6 8.5 0.2 16.9 3.4 3.8 0.0 16.9 0.2 1.5 62.4 9.4 0.0 0.2 1.3 5.7 0.3 2.1 0.0 49.7 0.0 4.7 0.0 0.3 6.7 0.0 0.5 12.3 20.4 5.2 0.0 0.1 0.6 9.0 9.8 5.3 7.4 0.0 12.3 30.9 17.5 20.0 0.4 93.6 0.0 0.1 0.3 1.7 1.1 0.0 0.0 0.2 0.0 1.5 0.0 0.2 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.3 43.4 10.8 45.8 47.5 11.5 13.1 10.5 13.5 10.0 15.9 25.9 76.7 3.2 6.7 1.6 5.8 3.4 4.2 1.4 1.8 17.3 29.8 20.4 19.5 17.2 5.1 31.3 6.2 74.4 0.9 109.8 39.2 9.7 1.5 7.6 1.3 51.5 8.4 8.0 20.7 16.6 68.2 5.6 2.0 11.7 0.0 59.0 18.9 121.3 6.4 0.0 2.0 25.6 6.1 4.7 2.7 2.8 3.1 1.4 8.8 5.6 4.8 10.4 0.0 0.0 1.4 13.9 55.5 19.2 0.0 11.0 255.7 58.2 1.9 3.9 0.0 2.1 4.6 0.5 5.5 0.8 1.7 183.9 1.2 54.9 25.1 2.6 C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0;lymphoid tissue: 134.5" "Cell type enhanced" "Detected in many" "granulocytes: 182.3;Hofbauer cells: 195.3;Kupffer cells: 797.4;Langerhans cells: 226.7;Macrophages: 413.5;monocytes: 278.6;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "HDLM-2: 141.3;HL-60: 70.4;NB-4: 40.3;THP-1: 55.2;U-937: 117.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA026988: AB_10600887" "unprognostic (8.79e-2)" "unprognostic (5.18e-3)" "unprognostic (1.14e-2)" "unprognostic (2.11e-1)" "unprognostic (5.20e-2)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.14e-6)" "unprognostic (1.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" 45.4 23.6 16.3 70.8 16.2 115.0 22.3 17.2 29.0 13.2 19.6 15.8 7.3 11.5 6.3 9.8 22.5 31.2 18.1 16.3 18.4 12.5 41.9 85.7 70.4 20.6 17.3 9.4 9.4 4.8 9.1 15.2 19.7 11.7 17.9 9.5 11.2 6.6 10.1 7.8 21.2 37.6 16.7 134.5 12.5 7.6 23.3 27.7 10.0 7.4 55.9 25.1 10.8 21.4 0.3 0.1 0.5 1.1 0.4 0.6 0.6 0.9 0.1 0.3 0.3 0.2 0.4 0.5 0.5 0.2 0.1 0.2 0.8 0.5 0.6 141.3 0.4 0.4 0.5 0.0 0.4 70.4 11.1 0.0 2.6 0.8 0.9 1.0 2.0 0.7 0.5 0.4 0.5 0.5 0.6 40.3 0.2 0.7 0.8 0.1 0.7 0.1 0.3 0.1 0.5 0.2 0.5 0.6 0.8 0.6 0.3 55.2 0.0 0.8 1.0 0.7 0.6 0.6 0.1 0.6 0.3 117.9 1.2 1114.1 1026.8 1294.8 166.6 1529.2 47.6 231.0 206.5 97.3 1021.6 296.4 318.0 193.6 143.3 536.7 1173.4 302.8 66.7 1189.5 16.3 16.2 17.2 29.0 16.3 18.4 20.6 17.3 19.7 16.7 23.3 21.4 4.4 22.4 43.9 8.1 84.1 7.9 0.7 0.4 0.6 4.0 2.2 5.2 3.8 10.0 4.5 7.3 2.1 1.0 103.4 0.6 0.0 0.2 36.7 0.8 0.9 8.1 1.8 23.5 9.2 0.2 2.0 3.2 0.5 1.0 182.3 0.9 15.7 8.9 195.3 0.0 13.0 0.0 0.0 797.4 226.7 90.7 2.8 413.5 12.4 12.2 278.6 0.2 355.3 6.0 7.7 0.2 0.0 0.7 4.2 0.8 0.9 1.0 0.9 4.2 32.9 2.4 2.9 2.4 2.0 0.2 6.5 1.6 59.8 0.3 0.7 0.3 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 23.7;Leydig cells: 23.3;Peritubular cells: 29.7;Skeletal myocytes: 16.9;Smooth muscle cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "RH-30: 34.4;U-138 MG: 15.1;U-2 OS: 8.3;WM-115: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" 2.8 0.6 0.9 0.7 0.9 0.1 1.9 1.2 1.3 4.7 0.1 2.5 1.2 3.3 1.1 1.4 2.3 1.8 3.9 0.9 0.8 0.6 0.4 2.4 0.3 0.3 1.3 1.3 0.3 0.2 0.5 0.8 0.2 1.9 1.1 0.2 1.3 1.0 1.9 1.4 2.3 1.8 0.2 0.6 2.0 1.8 2.5 0.1 2.1 2.1 0.3 2.1 2.6 0.8 0.3 0.0 0.5 0.1 0.0 0.0 0.0 3.9 5.3 0.9 3.3 0.1 0.9 0.0 0.1 1.4 0.6 0.2 0.1 0.4 0.2 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 34.4 0.0 0.0 0.2 0.0 0.8 1.0 0.1 0.2 0.1 0.4 0.1 0.2 15.1 8.3 1.5 4.4 0.1 0.0 0.0 0.5 0.0 6.8 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.9 0.9 1.2 1.3 0.9 0.8 0.3 1.3 0.2 0.2 2.5 0.8 2.0 0.0 0.0 0.0 0.0 6.5 0.2 0.2 0.6 0.8 0.3 0.4 1.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.1 0.0 0.1 1.0 4.2 0.0 0.0 0.6 0.2 0.3 23.7 0.5 0.2 0.0 0.2 1.1 0.0 1.1 0.0 6.2 0.1 0.0 0.0 6.2 0.4 23.3 0.5 5.4 1.0 0.6 0.1 0.0 1.0 0.3 0.1 0.1 29.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 16.9 22.8 0.1 0.5 0.6 3.8 0.8 0.3 2.1 0.1 0.3 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 2915.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 687.0;Hepatocytes: 2795.1;Leydig cells: 1193.2;Peritubular cells: 640.1" "Cancer enhanced" "Detected in all" "liver cancer: 276.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "ASC diff: 769.5;ASC TERT1: 1012.7;BJ hTERT+: 336.1;HSkMC: 540.2" "Not detected" "Not detected" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 93000000000 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 416.4 136.1 26.4 207.7 28.5 1.7 252.5 27.1 43.1 309.2 36.7 192.4 84.6 209.0 147.2 152.9 315.4 543.8 191.5 25.4 34.8 60.2 2915.2 224.9 209.2 44.3 31.7 485.9 62.1 21.8 33.1 52.9 31.2 174.4 215.2 9.7 96.9 139.1 57.0 104.1 154.2 251.8 30.9 168.5 150.1 90.0 30.9 88.1 139.0 154.7 192.5 455.7 189.8 31.3 0.2 18.6 1.2 10.2 769.5 1012.7 4.5 143.3 336.1 74.7 135.7 0.9 2.0 0.5 19.7 179.6 20.2 1.1 0.3 2.1 6.7 0.7 0.7 0.5 5.6 48.2 230.3 1.8 0.9 540.2 2.8 60.2 4.4 94.2 0.1 0.2 0.4 0.1 9.9 0.0 0.4 1.6 10.3 0.0 0.6 0.2 1.1 1.5 3.1 2.5 0.8 0.9 86.6 1.8 2.1 17.4 0.1 0.0 0.5 34.2 2.6 133.8 0.2 0.6 0.5 0.8 73.6 1.2 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 26.4 28.5 27.1 43.1 25.4 34.8 44.3 31.7 31.2 30.9 30.9 31.3 37.6 16.0 41.0 9.4 5.7 76.2 18.9 22.2 23.9 0.9 4.5 15.4 21.5 171.6 15.5 3.7 0.0 3.7 0.7 0.1 1.9 285.2 6.6 8.7 272.4 30.6 0.0 112.2 2.9 42.9 2.5 687.0 11.2 7.3 5.1 25.7 93.5 2795.1 8.1 5.0 1.7 0.0 2.0 62.8 103.7 29.9 1193.2 6.4 88.9 19.7 1.0 15.2 0.0 1.5 0.6 31.7 0.1 640.1 1.8 9.7 0.0 7.1 4.6 1.1 138.1 34.9 127.6 6.3 5.3 6.3 53.8 2.6 12.8 30.7 0.2 5.2 C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945672 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 477.9" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 142.4;Hepatocytes: 380.3;Hofbauer cells: 282.7;Kupffer cells: 99.3" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "intermediate monocyte: 21.1;non-classical monocyte: 25.9" "Lineage enriched" "Detected in single" 35 "monocytes: 25.9" "Cell line enriched" "Detected in some" 5 "Karpas-707: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB016775 Supported "Secreted to blood" NA NA 34000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" 42.6 12.1 0.8 27.6 1.0 3.2 11.7 0.9 1.4 8.1 1.7 14.3 16.7 7.0 1.3 7.6 12.0 23.0 8.5 0.7 1.1 23.2 477.9 80.0 27.8 3.0 2.6 5.3 1.9 0.9 3.8 48.4 3.0 5.4 13.0 0.4 9.1 0.9 2.1 5.8 30.2 23.6 2.1 46.3 12.0 4.1 3.7 5.5 3.3 2.7 12.5 23.6 5.3 2.1 0.3 0.1 0.1 0.6 0.1 0.0 6.8 0.5 0.3 0.4 0.3 0.4 0.3 0.6 3.5 1.0 0.6 0.5 0.1 0.0 0.3 0.2 0.4 0.3 0.4 52.8 1.1 0.1 0.7 2.7 0.3 0.6 0.1 0.6 0.0 0.7 0.5 284.0 0.0 0.0 0.4 0.5 0.3 0.1 0.0 0.2 16.5 3.0 0.0 0.1 0.3 0.3 2.6 0.3 0.2 0.3 0.2 9.5 0.2 0.2 0.7 0.5 0.1 0.9 31.6 2.7 0.8 0.9 0.1 0.1 5.6 0.0 0.1 21.1 0.1 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.5 0.1 25.9 0.0 0.0 2.2 0.8 1.0 0.9 1.4 0.7 1.1 3.0 2.6 3.0 2.1 3.7 2.1 2.1 25.6 142.4 2.6 1.9 3.3 1.1 2.0 0.6 1.4 1.3 1.3 0.6 25.8 11.2 1.8 0.0 2.1 0.1 1.8 0.0 0.6 0.3 1.5 18.7 1.9 2.4 10.7 6.6 2.7 2.7 19.8 3.1 1.3 3.8 0.2 21.0 380.3 282.7 1.7 6.3 11.3 0.0 99.3 5.0 1.3 6.8 32.6 3.6 7.5 7.3 0.1 0.0 1.0 1.7 4.5 33.1 1.2 0.4 4.0 55.2 35.7 9.4 0.9 0.0 5.6 3.5 0.8 1.4 0.7 2.8 4.0 2.0 0.5 15.8 4.5 C2CD2 "C21orf25, C21orf258, DKFZP586F0422, TMEM24L" ENSG00000157617 "C2 calcium dependent domain containing 2" Q9Y426 21 41885112-41954018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 126.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 51.6;Cone photoreceptor cells: 83.4;Granulosa cells: 100.0;Theca cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 79.1;SK-BR-3: 44.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030922, HPA030924" Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA030922: AB_2673660, HPA030924: AB_10669873" "unprognostic (3.02e-3)" "unprognostic (3.69e-2)" "unprognostic (2.21e-2)" "unprognostic (9.63e-2)" "unprognostic (3.15e-3)" "unprognostic (2.93e-2)" "unprognostic (2.39e-2)" "unprognostic (3.44e-2)" "unprognostic (3.00e-2)" "unprognostic (4.39e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.68e-5)" "unprognostic (1.99e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-2)" "unprognostic (1.48e-1)" 39.9 126.3 18.6 8.3 18.0 1.3 23.3 18.4 19.8 12.0 16.9 12.9 4.9 8.3 8.4 10.7 9.4 8.3 7.5 16.4 18.6 10.1 8.6 7.9 9.7 21.8 20.9 18.9 11.3 29.2 7.2 5.2 20.2 17.3 5.8 24.6 10.8 11.5 2.8 15.6 9.0 7.8 20.5 41.4 11.7 3.3 23.4 6.7 8.5 4.1 7.9 12.8 11.4 26.1 13.4 5.5 3.9 8.9 79.1 21.7 15.1 9.3 14.4 5.7 5.2 8.7 15.0 0.2 5.0 18.0 14.0 1.5 13.9 9.7 7.2 0.9 6.2 2.3 7.1 7.1 10.6 1.0 0.0 14.0 8.9 30.3 11.7 12.5 27.1 0.7 8.4 0.1 15.3 1.2 1.9 2.7 21.4 5.7 18.7 1.4 5.7 8.0 8.5 27.8 6.3 2.8 10.1 44.6 8.1 7.6 11.7 5.9 9.3 13.5 1.9 4.5 7.6 5.0 7.9 1.1 39.2 7.7 2.8 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.2 0.1 0.3 0.1 0.5 0.3 0.1 0.3 0.1 0.0 0.3 0.1 18.6 18.0 18.4 19.8 16.4 18.6 21.8 20.9 20.2 20.5 23.4 26.1 24.8 3.2 15.5 20.5 4.4 4.1 9.1 7.6 15.9 51.6 8.2 7.0 3.1 8.6 8.3 3.7 83.4 12.8 4.4 3.4 0.0 5.6 0.3 6.0 6.7 19.3 4.9 5.9 20.3 8.5 4.8 11.9 17.9 8.3 0.0 100.0 46.1 5.2 3.6 1.7 14.4 6.9 6.1 7.0 10.5 0.2 3.7 5.6 1.8 24.4 2.5 3.6 3.1 11.6 18.8 8.1 5.0 2.2 8.1 15.9 3.0 2.5 7.7 36.9 13.1 7.4 17.9 0.1 3.0 14.3 2.6 9.3 2.8 82.4 6.9 16.6 C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "granulocytes: 36.8;Hofbauer cells: 161.5;Kupffer cells: 139.7;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 898.6;eosinophil: 450.8;intermediate monocyte: 273.6;non-classical monocyte: 371.3" "Group enriched" "Detected in many" 20 "granulocytes: 898.6;monocytes: 371.3" "Cell line enriched" "Detected in some" 9 "HMC-1: 148.0" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" 18.0 10.6 3.8 40.1 4.0 22.9 6.7 4.7 5.7 6.8 4.4 7.4 6.6 3.8 1.5 3.9 5.9 16.2 4.4 3.9 6.9 3.1 10.8 18.6 12.4 10.1 6.3 3.7 6.0 3.3 2.5 22.0 9.0 3.3 6.8 0.8 5.6 4.3 1.4 2.0 9.7 15.6 8.3 21.4 5.3 2.1 7.8 4.9 2.4 2.6 5.1 15.2 2.7 15.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.9 0.5 3.8 0.0 0.0 1.6 0.0 0.0 2.2 0.1 0.0 0.0 0.1 0.0 0.0 12.0 0.0 0.0 1.4 15.6 148.0 0.7 0.0 0.2 0.4 0.3 0.7 1.2 4.0 8.2 0.7 0.0 0.7 5.2 0.1 0.0 0.0 0.1 3.1 15.1 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 6.6 0.6 0.5 0.4 0.1 0.3 0.3 0.0 0.4 8.5 6.4 0.4 898.6 105.0 450.8 21.8 273.6 26.9 0.2 10.6 14.5 31.1 0.3 2.0 7.8 14.0 4.1 371.3 2.8 11.0 76.0 3.8 4.0 4.7 5.7 3.9 6.9 10.1 6.3 9.0 8.3 7.8 15.6 0.7 0.0 3.0 0.3 1.1 0.5 0.1 0.1 0.0 0.1 0.3 0.9 0.6 1.5 2.5 0.0 2.1 0.7 5.9 0.0 0.0 0.0 3.0 0.0 0.1 6.6 0.0 0.8 0.4 0.2 1.0 0.6 0.0 0.0 36.8 0.0 1.8 0.8 161.5 0.0 0.3 0.0 0.0 139.7 19.8 4.2 1.2 105.7 0.0 8.4 16.2 0.0 8.2 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.7 0.4 19.7 0.7 1.0 0.0 0.2 0.0 0.6 1.5 8.6 0.1 0.0 0.0 C4orf19 FLJ11017 ENSG00000154274 "Chromosome 4 open reading frame 19" Q8IY42 4 37453925-37623495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.0" "Cell type enhanced" "Detected in many" "Astrocytes: 45.4;Distal enterocytes: 61.3;Exocrine glandular cells: 51.8;Oligodendrocyte precursor cells: 46.8;Pancreatic endocrine cells: 53.6;Paneth cells: 67.2;Proximal enterocytes: 52.3;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 8.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.6" "Group enriched" "Detected in some" 5 "OE19: 64.6;RT4: 81.0;SK-BR-3: 32.6;T-47d: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043458, HPA052894" Enhanced Supported "Cell Junctions" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA043458: AB_10960696, HPA052894: AB_2681982" "unprognostic (8.83e-2)" "unprognostic (7.86e-2)" "unprognostic (3.00e-3)" "unprognostic (2.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.59e-3)" "unprognostic (5.55e-2)" "unprognostic (2.29e-1)" "unprognostic (6.66e-2)" "unprognostic (9.96e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.49e-11)" "unprognostic (1.33e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-3)" "unprognostic (8.19e-3)" 3.4 0.3 2.7 3.0 2.9 3.8 3.8 5.3 4.3 10.2 5.9 25.5 17.7 6.7 0.2 2.1 2.8 9.2 0.4 3.5 4.2 12.4 36.0 3.7 0.5 4.9 4.9 0.2 24.9 16.0 1.2 7.6 4.2 1.7 23.7 4.6 28.2 6.8 0.2 1.6 19.6 4.0 4.5 0.3 20.7 1.4 4.9 0.2 1.5 0.4 4.3 8.8 2.9 4.1 0.1 0.2 3.2 0.3 0.0 0.0 4.2 0.7 0.0 0.0 0.0 12.6 5.2 0.1 3.0 0.0 0.1 0.4 0.2 0.8 0.1 0.0 0.4 0.0 8.3 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 14.3 0.2 0.2 0.5 64.6 1.7 0.1 7.8 0.2 12.7 81.0 0.9 0.3 0.5 32.6 1.0 4.0 113.1 0.7 0.6 0.4 4.5 0.2 1.6 0.2 0.1 0.5 0.0 6.9 5.6 0.9 1.4 2.1 0.6 0.2 0.4 0.2 0.3 0.4 0.2 0.5 0.5 0.8 8.6 0.8 0.1 1.6 0.7 0.3 2.7 2.9 5.3 4.3 3.5 4.2 4.9 4.9 4.2 4.5 4.9 4.1 0.3 0.0 12.6 45.4 0.7 0.3 7.8 4.9 0.0 0.6 7.1 3.9 0.2 27.1 10.1 11.0 0.0 6.7 0.2 61.3 11.7 25.2 1.2 9.5 0.4 0.9 9.6 0.0 2.3 51.8 4.7 0.3 33.6 5.5 0.0 0.0 0.0 13.1 0.7 0.0 2.4 28.0 4.1 0.0 0.3 2.4 0.0 0.2 3.6 22.5 0.6 5.3 0.0 46.8 1.8 53.6 67.2 0.0 0.0 7.8 52.3 9.2 12.3 1.0 0.0 0.2 0.9 0.3 0.2 0.5 0.0 47.5 0.4 0.1 31.8 19.1 C6orf132 bA7K24.2 ENSG00000188112 "Chromosome 6 open reading frame 132" Q5T0Z8 6 42101119-42142620 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 157.0;skin 1: 73.6" "Cell type enhanced" "Detected in many" "Late spermatids: 163.8;Pancreatic endocrine cells: 219.9;Prostatic glandular cells: 144.6;Urothelial cells: 226.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 57.8;CACO-2: 52.0;CAPAN-2: 44.0;OE19: 181.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA044588 Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Cytosol" "HPA044588: AB_10794293" "unprognostic (7.09e-2)" "unprognostic (8.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.24e-3)" "unprognostic (1.60e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (6.78e-2)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (4.90e-4)" "unprognostic (1.31e-1)" "unprognostic (4.26e-3)" "unprognostic (1.04e-2)" "unprognostic (5.53e-2)" "unprognostic (2.47e-2)" "unprognostic (1.30e-1)" 3.7 1.0 0.4 2.2 0.4 1.0 8.7 0.6 0.7 31.7 0.3 14.1 33.4 1.0 0.1 157.0 5.8 6.6 1.8 0.4 0.1 14.9 0.5 5.8 0.3 0.4 0.1 0.2 18.0 2.5 1.7 1.5 0.4 12.1 11.7 0.9 47.1 2.3 0.9 73.6 20.7 0.5 0.0 0.1 36.2 0.7 0.3 0.7 10.7 0.3 13.9 9.9 54.9 0.6 57.8 0.5 0.0 0.1 0.3 6.1 29.0 2.9 4.4 7.6 7.6 52.0 44.0 0.0 5.4 5.4 0.1 37.5 0.1 17.3 5.2 5.1 7.2 2.8 5.0 12.1 2.0 0.0 0.2 4.0 30.4 5.9 8.8 3.1 0.0 0.3 1.7 0.5 1.7 20.4 0.4 0.3 3.6 181.7 1.5 0.1 0.0 0.3 6.2 25.5 3.0 0.1 4.7 35.2 0.1 4.1 25.2 0.3 0.8 0.4 3.5 13.5 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.5 0.2 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.5 0.1 0.0 0.3 0.0 0.1 0.4 0.4 0.6 0.7 0.4 0.1 0.4 0.1 0.4 0.0 0.3 0.6 0.8 44.8 16.6 0.3 0.2 52.5 88.6 31.8 19.4 0.8 41.7 19.8 5.1 45.8 63.1 51.5 20.9 12.4 1.2 89.9 0.0 57.9 22.2 91.9 9.4 2.8 7.3 0.0 0.5 134.7 1.0 9.2 57.1 135.8 1.3 18.3 1.4 0.0 0.8 5.0 0.5 41.3 38.7 1.2 6.8 163.8 0.6 1.5 12.4 0.0 3.8 0.5 4.1 0.5 0.2 219.9 66.8 1.5 0.3 144.6 102.7 7.7 92.1 7.9 0.0 7.9 4.9 4.9 9.1 81.4 82.0 4.1 1.5 45.4 43.7 226.0 C9orf152 bA470J20.2 ENSG00000188959 "Chromosome 9 open reading frame 152" Q5JTZ5 9 110190048-110208159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.6;salivary gland: 25.4;stomach 1: 32.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.4;Intestinal goblet cells: 139.7;Ionocytes: 40.7;Paneth cells: 40.0;Undifferentiated cells: 79.8" "Cancer enhanced" "Detected in many" "prostate cancer: 27.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 149.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA050769 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Nucleoli "HPA050769: AB_2681230" "unprognostic (1.90e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "prognostic favorable (7.22e-5)" "unprognostic (2.28e-1)" "unprognostic (1.79e-3)" "unprognostic (6.86e-2)" "unprognostic (1.34e-1)" "unprognostic (4.84e-2)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (5.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (4.57e-1)" "unprognostic (2.49e-1)" "unprognostic (1.06e-2)" 0.1 0.0 0.5 2.1 0.4 0.0 12.4 0.2 0.4 10.4 0.1 32.8 19.0 2.3 0.0 3.0 3.7 5.5 0.0 0.4 0.1 0.2 0.8 5.8 0.0 0.6 0.4 0.0 5.1 0.0 0.1 0.0 0.6 17.0 41.6 0.0 25.4 1.4 0.0 5.4 15.1 1.2 0.2 0.1 32.9 0.0 0.5 0.1 0.1 0.0 0.2 1.2 0.4 0.6 0.0 1.3 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.1 0.0 149.2 0.2 0.0 0.0 0.2 0.0 0.6 0.1 0.1 0.0 9.3 0.0 0.0 18.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.2 0.4 0.4 0.1 0.6 0.4 0.6 0.2 0.5 0.6 0.4 9.6 16.3 0.3 0.2 0.3 3.4 5.9 6.2 0.0 20.5 10.8 0.1 20.0 14.5 0.0 0.0 0.0 0.1 35.4 0.0 6.0 0.0 4.0 2.0 0.5 25.9 0.0 0.1 11.1 0.0 0.2 25.0 13.9 0.0 0.0 0.0 3.3 0.1 0.0 0.1 139.7 40.7 0.0 1.0 0.0 0.0 0.6 10.6 0.0 0.0 0.0 0.0 0.0 0.1 3.9 40.0 0.0 0.0 12.4 4.4 0.0 5.2 0.0 0.0 0.4 0.9 0.0 0.0 10.9 0.4 0.0 0.4 0.0 79.8 5.5 CADPS "CAPS, CAPS1, KIAA1121, UNC-31" ENSG00000163618 "Calcium dependent secretion activator" Q9ULU8 3 62398346-62875416 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.6;retina: 184.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 772.6;Cone photoreceptor cells: 627.6;Excitatory neurons: 830.8;Inhibitory neurons: 1152.7;Oligodendrocyte precursor cells: 266.9" "Cancer enhanced" "Detected in many" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 11.5;SCLC-21H: 19.7;SK-MEL-30: 9.0;U-698: 13.2;U-87 MG: 20.5" HPA059328 Enhanced Supported Approved Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA059328: AB_2683982" "unprognostic (3.46e-3)" "unprognostic (1.40e-2)" "unprognostic (1.61e-2)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (3.12e-2)" "unprognostic (9.27e-2)" "unprognostic (5.73e-2)" "unprognostic (2.08e-3)" "unprognostic (3.21e-1)" "unprognostic (4.20e-3)" "unprognostic (1.90e-2)" "unprognostic (2.04e-1)" "unprognostic (7.91e-3)" "unprognostic (5.35e-3)" 0.4 16.4 32.2 2.0 47.7 0.1 0.7 18.7 84.6 2.8 0.0 2.8 3.2 0.6 2.5 0.2 0.4 2.4 16.7 32.1 26.0 0.2 0.2 0.8 0.5 83.2 39.7 1.9 13.5 0.2 39.6 0.2 84.5 3.6 2.4 184.3 1.4 2.8 0.1 1.4 3.3 0.8 4.1 0.6 3.0 3.2 33.0 0.6 0.2 0.0 0.7 0.4 1.4 61.7 0.0 0.0 0.8 0.0 4.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.5 11.5 0.0 0.1 0.0 0.0 0.0 0.0 19.7 1.5 0.0 0.0 9.0 0.4 0.0 0.0 0.1 1.6 0.1 3.3 0.9 0.0 1.7 13.2 20.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 47.7 18.7 84.6 32.1 26.0 83.2 39.7 84.5 4.1 33.0 61.7 0.0 0.0 1.9 93.0 0.1 1.3 0.2 0.0 0.0 772.6 0.5 2.8 25.6 7.2 0.0 0.0 627.6 0.1 0.0 0.4 0.0 4.1 1.1 0.2 1.1 0.9 95.9 0.0 830.8 0.4 0.0 3.2 0.0 0.1 42.5 0.2 0.0 0.0 0.0 47.1 1152.7 5.0 0.0 0.0 1.6 2.1 15.2 0.0 8.8 30.0 0.0 21.3 0.0 266.9 27.0 0.9 1.3 2.6 0.0 0.3 0.7 0.1 0.0 64.7 0.0 3.2 1.2 0.2 0.7 0.0 0.1 0.0 0.4 36.9 1.8 0.2 CALML3 CLP ENSG00000178363 "Calmodulin like 3" P27482 10 5524961-5526771 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 507.1;skin 1: 179.0;vagina: 200.8" "Cell type enriched" "Detected in some" 8 "Squamous epithelial cells: 1257.1" "Cancer enhanced" "Detected in many" "cervical cancer: 150.9;head and neck cancer: 196.3" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 21.5;hTCEpi: 8.6;RPMI-8226: 6.0" "Not detected" "Not detected" "CAB010070, HPA044999" Approved NA NA 1200000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB010070: , HPA044999: AB_2679177" "unprognostic (1.02e-3)" "unprognostic (1.18e-2)" "unprognostic (4.33e-2)" "unprognostic (1.37e-1)" "unprognostic (1.29e-2)" "unprognostic (2.16e-1)" "unprognostic (2.93e-1)" "unprognostic (3.11e-1)" "unprognostic (1.02e-2)" "unprognostic (9.64e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-2)" "unprognostic (1.71e-1)" "unprognostic (2.56e-1)" "unprognostic (1.65e-1)" "unprognostic (4.43e-3)" 0.5 0.1 0.2 0.0 0.2 0.0 5.4 1.5 0.1 107.9 0.0 0.1 0.0 0.1 0.1 507.1 1.2 0.0 0.1 0.0 0.3 17.3 1.6 0.0 0.0 0.5 0.3 0.1 0.2 0.0 0.3 0.0 0.2 2.9 0.0 0.0 121.0 0.1 1.0 179.0 0.2 0.0 0.0 0.1 0.3 1.7 0.7 79.5 0.1 0.0 39.8 0.2 200.8 0.0 21.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.5 0.1 0.0 0.3 0.5 0.3 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 28.4 29.8 6.3 157.1 2.2 13.3 22.4 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 5.9 0.0 4.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 28.5 0.0 1.4 8.3 0.3 0.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 6.5 0.0 59.6 0.7 0.3 0.0 0.0 0.9 6.7 0.1 1257.1 55.0 0.0 0.7 0.0 0.2 30.6 CALML5 CLSP ENSG00000178372 "Calmodulin like 5" Q9NZT1 10 5498697-5499570 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 3060.6" "Group enriched" "Detected in some" 4 "Breast glandular cells: 172.1;Breast myoepithelial cells: 156.1;Suprabasal keratinocytes: 390.7" "Group enriched" "Detected in many" 6 "breast cancer: 97.6;cervical cancer: 189.1;head and neck cancer: 206.0;melanoma: 222.1;urothelial cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "A-431: 400.3" "Not detected" "Not detected" HPA040725 Enhanced Approved "Plasma membrane,Cytosol" NA NA 48000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA040725: AB_10793863" "unprognostic (7.68e-3)" "unprognostic (5.06e-3)" "unprognostic (5.64e-2)" "prognostic favorable (2.59e-5)" "unprognostic (4.82e-2)" "unprognostic (2.67e-1)" "unprognostic (1.37e-1)" "unprognostic (8.27e-2)" "unprognostic (1.14e-1)" "unprognostic (2.79e-1)" "unprognostic (1.71e-1)" "unprognostic (4.99e-2)" 3.9 0.5 0.0 0.0 0.0 0.1 41.2 0.0 0.0 94.0 0.0 0.8 0.0 0.3 0.7 67.5 0.1 0.0 1.3 0.0 0.0 0.3 1.7 0.8 0.0 0.0 0.0 0.4 1.1 0.0 0.5 0.0 0.0 0.5 0.0 0.0 554.0 0.0 11.7 3060.6 0.6 0.0 0.0 0.4 0.8 1.0 0.0 9.2 0.6 0.0 13.4 0.1 306.6 0.0 400.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 7.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.8 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 27.3 0.3 2.2 0.0 0.0 172.1 156.1 0.2 0.0 1.8 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 11.1 0.0 0.0 0.4 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 1.3 0.2 0.3 6.8 390.7 0.0 1.2 0.0 0.0 3.3 CAMK2N1 CaMKIINalpha ENSG00000162545 "Calcium/calmodulin dependent protein kinase II inhibitor 1" Q7Z7J9 1 20482391-20486210 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 461.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 640.5;Intestinal goblet cells: 431.4;Paneth cells: 367.7;Proximal tubular cells: 519.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6;MAIT T-cell: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Cell line enhanced" "Detected in many" "AN3-CA: 212.1;CAPAN-2: 199.1;Hep G2: 165.6;SK-BR-3: 159.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075200 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA075200: " "unprognostic (1.67e-1)" "unprognostic (2.70e-3)" "unprognostic (9.71e-3)" "unprognostic (3.13e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (1.37e-7)" "prognostic unfavorable (5.49e-4)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.77e-2)" "unprognostic (1.31e-1)" "unprognostic (7.48e-3)" "unprognostic (1.93e-2)" "unprognostic (1.40e-3)" "unprognostic (4.44e-2)" "unprognostic (1.19e-1)" "unprognostic (1.96e-2)" "unprognostic (1.31e-2)" 20.1 61.6 340.5 9.3 322.3 0.5 19.8 172.0 461.3 32.5 115.4 85.0 80.4 27.8 38.1 27.8 22.3 27.4 22.3 354.6 206.5 86.2 53.8 67.9 1.9 224.8 222.4 30.2 8.8 42.4 37.7 11.6 215.9 35.8 77.0 32.6 30.4 40.8 7.1 12.0 86.9 22.7 226.7 12.2 19.5 4.7 265.4 2.0 10.8 9.9 7.0 27.3 24.3 348.6 63.1 17.5 15.0 212.1 28.4 52.6 2.2 52.6 119.0 9.5 4.8 20.1 199.1 6.3 14.7 21.7 7.7 103.2 4.6 90.0 5.9 11.7 3.8 1.3 0.9 165.6 31.4 0.1 6.2 8.4 41.2 5.6 21.2 19.6 16.4 4.3 6.3 0.5 105.8 17.4 0.2 0.5 2.8 109.7 3.9 5.6 9.4 0.4 59.3 93.5 57.6 16.2 28.5 159.6 16.3 10.2 30.6 0.6 5.0 34.9 46.1 48.5 21.1 0.1 0.1 2.5 119.5 13.5 22.0 0.0 0.0 0.0 1.6 0.0 1.1 0.5 0.5 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 340.5 322.3 172.0 461.3 354.6 206.5 224.8 222.4 215.9 226.7 265.4 348.6 28.3 3.2 1.1 35.6 7.6 9.3 11.7 2.3 0.6 248.6 96.5 104.5 20.8 178.7 2.5 248.3 6.2 0.5 10.1 640.5 229.0 20.1 0.8 6.2 45.6 20.0 299.2 8.0 132.5 40.8 2.9 65.1 9.2 12.0 1.3 4.6 9.3 201.6 0.3 85.8 108.7 431.4 14.2 1.9 12.1 3.9 62.7 5.6 39.2 26.2 0.6 81.1 0.0 27.6 249.1 141.5 367.7 94.0 3.5 37.7 183.2 519.2 1.2 35.6 131.5 86.2 96.4 0.8 2.8 1.0 7.5 2.1 14.7 0.8 223.5 50.3 CAMK4 "CaMK-GR, CaMKIV" ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 70.4;lymphoid tissue: 55.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 70.9;Early spermatids: 306.2;Excitatory neurons: 212.2;Inhibitory neurons: 131.8;Late spermatids: 108.4;Oligodendrocyte precursor cells: 133.2;T-cells: 83.3" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 6 "basal ganglia: 30.6;cerebellum: 70.4" "Group enriched" "Detected in many" 4 "MAIT T-cell: 24.3;memory CD4 T-cell: 17.3;memory CD8 T-cell: 13.5;naive CD4 T-cell: 33.1;naive CD8 T-cell: 18.5;T-reg: 21.3" "Lineage enriched" "Detected in many" 23 "T-cells: 33.1" "Cell line enhanced" "Detected in many" "HDLM-2: 88.9;JURKAT: 61.3;MOLT-4: 27.9;SH-SY5Y: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 0.4 3.8 5.0 4.4 30.6 3.1 0.4 70.4 8.2 0.9 0.0 1.3 1.4 0.6 0.3 0.7 0.3 1.5 0.1 7.6 0.0 0.7 1.4 1.1 8.1 0.0 0.4 0.6 0.4 0.0 0.6 0.2 1.4 3.4 1.4 4.7 0.4 1.4 0.1 0.1 2.3 0.8 0.0 2.6 1.5 9.4 0.8 55.4 0.2 0.0 5.2 1.7 0.4 0.0 0.0 0.0 3.1 2.1 0.6 2.3 0.0 0.8 6.8 8.0 7.8 0.0 0.1 0.0 4.0 0.4 5.4 0.3 6.8 0.8 5.8 88.9 5.2 1.3 2.8 0.0 0.2 0.6 0.3 0.3 0.0 16.8 1.7 4.9 1.4 61.3 0.0 3.3 0.4 0.0 27.9 0.0 4.1 0.0 0.2 4.0 5.0 0.2 2.9 0.1 18.8 33.5 1.2 0.0 5.6 0.2 0.1 0.5 0.1 16.3 9.5 0.1 14.7 2.6 0.3 0.0 8.0 0.0 6.3 0.1 0.0 0.0 4.8 0.0 24.3 1.3 17.3 13.5 0.0 0.3 33.1 18.5 0.9 1.4 0.0 0.1 21.3 5.5 5.0 30.6 70.4 8.2 7.6 0.0 0.0 0.4 1.4 0.0 0.8 0.0 1.8 0.0 1.1 57.8 9.4 1.1 0.3 1.3 8.6 70.9 0.6 0.6 5.3 0.0 0.0 0.0 0.0 0.1 3.1 0.1 0.0 0.1 306.2 0.2 1.6 1.1 0.0 0.0 212.2 0.0 0.2 4.6 3.6 0.4 4.5 0.3 0.7 0.3 0.2 0.0 131.8 0.8 0.0 1.3 2.1 108.4 4.1 2.0 0.0 12.2 2.7 2.8 1.0 133.2 5.4 1.2 0.0 1.5 11.5 0.5 0.0 0.1 0.1 4.3 0.0 0.6 3.8 30.3 6.2 2.4 1.0 0.0 83.3 0.1 0.0 0.3 CAPSL MGC26610 ENSG00000152611 "Calcyphosine like" Q8WWF8 5 35904288-35938779 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "fallopian tube: 110.9" "Cell type enhanced" "Detected in some" "Early spermatids: 167.1;Endometrial ciliated cells: 400.1;Late spermatids: 148.9;Respiratory ciliated cells: 709.5" "Cancer enriched" "Detected in many" 4 "endometrial cancer: 14.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 7.3;BJ hTERT+ SV40 Large T+ RasG12V: 6.2;HBF TERT88: 4.7;REH: 8.0;U-698: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA046811, HPA058495" Enhanced Approved Nucleoplasm,Microtubules No No "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Microtubules" "HPA046811: AB_2679819, HPA058495: AB_2683735" "unprognostic (1.16e-1)" "unprognostic (3.40e-2)" "unprognostic (2.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.20e-2)" "unprognostic (7.35e-2)" "unprognostic (1.29e-1)" "unprognostic (1.92e-3)" "unprognostic (4.42e-1)" "unprognostic (3.62e-4)" "unprognostic (1.46e-1)" "unprognostic (1.36e-2)" "unprognostic (1.52e-1)" 0.0 0.0 3.3 0.0 2.8 0.2 0.1 1.9 2.1 2.5 25.4 0.0 0.0 2.0 8.4 0.0 110.9 0.0 0.0 2.1 3.6 0.8 0.0 7.7 0.0 9.9 10.2 0.1 0.5 1.2 13.6 0.0 7.5 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 8.0 0.0 0.1 9.9 4.0 6.6 5.4 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.8 7.3 6.2 0.0 0.0 2.2 0.0 1.0 0.1 0.0 0.1 0.0 4.7 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 1.3 0.0 0.0 1.2 2.1 0.0 0.5 0.0 0.0 19.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 2.8 1.9 2.1 2.1 3.6 9.9 10.2 7.5 8.0 4.0 7.6 0.0 3.2 7.3 0.3 0.0 0.0 0.1 58.0 0.0 0.0 0.2 0.0 0.0 0.0 66.2 1.8 0.0 0.0 0.0 0.0 1.9 0.1 167.1 400.1 2.4 0.5 0.0 0.0 0.4 0.0 0.0 0.8 0.0 4.7 1.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 65.1 0.0 0.0 148.9 0.9 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.5 0.0 1.6 709.5 0.0 0.0 0.0 19.2 21.0 1.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3043867 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "B-cells: 34.9;dendritic cells: 47.2;Microglial cells: 49.6;NK-cells: 28.8;Pancreatic endocrine cells: 24.9;Plasma cells: 26.7;T-cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 31.4" "Cell line enhanced" "Detected in many" "Daudi: 122.7;K-562: 50.1;RT4: 91.4;U-698: 108.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA052984: AB_2682005" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (4.81e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.65e-2)" "unprognostic (5.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-8)" "unprognostic (3.74e-2)" "unprognostic (4.75e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.10e-4)" 1.3 3.1 6.9 21.8 1.5 18.5 1.2 1.8 1.5 2.3 1.0 2.4 3.7 1.3 0.2 1.3 2.2 8.8 1.0 1.3 4.9 1.6 1.6 4.7 47.3 4.2 8.4 1.3 1.4 0.7 0.9 0.5 3.7 1.4 2.3 0.2 3.3 1.6 0.6 0.7 18.3 0.6 3.0 31.5 7.5 1.7 14.0 20.9 1.5 0.2 29.5 17.1 1.3 4.6 16.7 2.6 0.1 0.1 0.0 0.0 12.2 0.1 0.0 0.5 0.0 32.4 35.5 122.7 29.2 0.0 0.0 27.2 0.0 0.4 0.3 42.1 1.1 0.1 3.1 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.8 23.1 13.3 50.1 0.0 0.0 0.3 4.7 0.0 44.9 20.6 0.1 5.9 0.1 30.7 11.4 91.4 0.3 1.5 0.1 0.2 0.1 17.7 0.2 2.5 15.4 0.2 11.8 0.1 0.1 12.3 0.1 108.0 0.0 0.0 0.2 0.5 0.0 0.0 7.7 0.0 7.2 5.4 4.4 5.2 0.9 6.2 2.9 5.3 0.2 5.5 0.0 31.4 3.5 2.9 6.9 1.5 1.8 1.5 1.3 4.9 4.2 8.4 3.7 3.0 14.0 4.6 0.5 0.0 0.0 0.7 34.9 0.0 0.3 0.3 0.6 0.6 0.3 0.4 2.0 0.0 0.3 1.8 0.0 0.0 47.2 0.7 0.0 4.6 0.2 0.4 0.3 0.6 0.0 0.8 2.1 5.3 0.0 1.6 14.3 0.7 5.7 8.6 0.4 0.2 1.5 0.0 1.6 0.3 0.0 2.4 1.8 0.4 0.3 5.4 3.6 49.6 1.0 0.1 28.8 1.0 0.6 24.9 0.0 0.0 26.7 0.3 0.0 0.1 1.0 0.2 0.0 0.3 0.9 1.5 0.2 0.0 0.3 0.0 28.6 4.5 0.4 8.1 CARHSP1 "CRHSP-24, CSDC1" ENSG00000153048 "Calcium regulated heat stable protein 1" Q9Y2V2 16 8852942-8869012 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 422.7" "Group enriched" "Detected in all" 7 "Early spermatids: 2062.2;Late spermatids: 6999.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051911 Enhanced NA Yes 280000 "Cluster 10: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA051911: AB_2681660" "unprognostic (4.08e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.15e-1)" "unprognostic (2.08e-3)" "unprognostic (8.57e-2)" "unprognostic (1.88e-3)" "unprognostic (2.03e-1)" "unprognostic (3.29e-1)" "unprognostic (2.61e-1)" "unprognostic (7.19e-3)" "unprognostic (1.76e-3)" "unprognostic (5.94e-2)" "unprognostic (1.10e-1)" "unprognostic (2.61e-1)" "prognostic favorable (7.24e-4)" 101.4 132.5 49.4 33.7 75.0 70.0 67.7 46.8 58.4 101.7 46.5 46.4 31.3 38.2 13.5 193.7 51.0 33.8 48.2 50.1 50.8 109.6 188.2 116.7 46.9 56.1 49.7 68.5 54.8 9.8 33.2 59.2 51.2 35.3 25.6 3.0 110.7 13.9 17.4 34.5 47.1 24.2 47.6 56.7 52.5 422.7 51.0 59.6 35.9 21.3 59.4 45.8 101.7 60.4 84.2 134.8 200.2 40.3 52.1 83.0 98.9 110.7 93.5 92.9 117.8 95.4 224.6 109.1 70.2 83.5 70.9 82.0 79.3 87.9 65.4 87.9 102.1 34.5 108.1 369.8 177.5 59.2 84.6 181.7 40.0 91.8 60.7 87.8 92.6 241.5 94.5 136.1 120.5 152.0 313.5 147.6 124.6 89.0 82.2 367.0 245.9 179.3 75.5 56.0 119.0 153.2 104.9 106.1 104.0 112.4 134.9 60.3 99.9 77.8 144.9 94.6 57.4 67.6 77.4 135.0 173.9 71.9 134.9 81.6 29.6 35.8 25.8 14.3 16.1 17.5 25.0 25.3 25.8 28.6 17.0 23.7 89.2 41.6 19.0 47.4 62.8 20.8 49.4 75.0 46.8 58.4 50.1 50.8 56.1 49.7 51.2 47.6 51.0 60.4 166.3 25.6 9.1 19.6 48.9 42.7 67.2 158.4 22.8 8.0 71.4 38.0 6.0 221.6 86.4 82.8 6.2 141.5 65.1 152.6 54.8 619.1 2062.2 101.9 82.0 145.3 144.9 147.5 4.4 241.8 312.6 86.4 42.8 114.4 39.3 118.0 128.8 323.5 70.5 11.8 5.9 107.7 91.6 62.4 55.3 6999.5 96.3 36.1 58.7 9.4 66.5 7.7 121.5 8.0 25.6 340.0 179.5 73.0 63.9 139.3 174.2 479.0 70.9 11.2 111.7 31.2 95.5 72.7 52.7 84.2 42.1 153.5 65.1 17.0 108.4 169.8 CARMIL2 "LRRC16C, RLTPR" ENSG00000159753 "Capping protein regulator and myosin 1 linker 2" Q6F5E8 16 67644988-67657569 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.4;intestine: 13.4;lymphoid tissue: 21.6" "Group enriched" "Detected in some" 4 "B-cells: 3.6;dendritic cells: 3.7;T-cells: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 64.2;JURKAT: 47.3;MOLT-4: 64.6;REH: 105.6;RPMI-8226: 58.4;U-698: 107.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041402 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA041402: AB_10795591" "unprognostic (1.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.35e-2)" "unprognostic (6.37e-2)" "unprognostic (5.47e-3)" "unprognostic (4.27e-4)" "unprognostic (1.38e-2)" "unprognostic (1.44e-1)" "unprognostic (3.85e-2)" "unprognostic (1.52e-1)" "unprognostic (7.90e-5)" "unprognostic (4.07e-2)" "unprognostic (5.14e-10)" "unprognostic (2.25e-1)" "unprognostic (1.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.57e-2)" 0.9 0.5 5.9 12.5 6.3 5.9 0.5 4.5 11.4 0.4 2.4 2.0 1.8 0.3 0.1 0.9 0.5 1.2 0.3 9.8 5.1 0.9 0.8 1.7 21.6 5.6 4.0 0.2 0.4 0.1 4.5 0.2 5.4 0.8 0.7 0.3 1.4 0.1 0.0 0.4 13.4 0.2 3.4 19.9 1.9 0.9 4.9 20.9 1.2 0.0 10.9 1.5 0.7 6.8 0.2 0.1 0.1 0.3 0.0 0.1 18.1 0.6 0.0 0.5 0.0 9.6 0.6 64.2 1.1 0.0 0.1 0.1 6.0 0.0 0.0 14.3 7.5 3.8 0.3 1.2 0.5 7.1 0.6 0.1 0.0 0.0 0.1 0.1 0.0 47.3 0.9 1.0 0.0 1.1 64.6 32.2 10.7 0.3 0.3 105.6 0.1 58.4 0.0 0.0 15.9 1.7 0.1 0.2 0.5 1.5 0.4 1.9 0.2 0.9 2.0 0.1 0.4 17.6 33.4 107.2 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.7 0.1 0.0 0.4 0.2 0.1 0.0 0.4 0.0 0.3 0.7 0.1 5.9 6.3 4.5 11.4 9.8 5.1 5.6 4.0 5.4 3.4 4.9 6.8 0.4 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.9 0.2 0.0 0.0 CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 135.8;Oligodendrocyte precursor cells: 447.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 47.1" "Lineage enriched" "Detected in many" 10 "granulocytes: 47.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "CAB001949: , HPA023857: AB_1846035" "unprognostic (6.30e-2)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-3)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (6.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "unprognostic (2.85e-2)" 10.2 11.1 13.6 11.9 12.9 7.3 15.7 12.3 11.1 11.6 12.4 25.3 32.1 11.1 9.4 13.7 10.5 18.5 6.8 14.2 17.1 16.4 13.4 12.2 12.5 13.2 19.4 13.5 12.8 11.8 6.3 16.3 15.7 10.6 27.3 19.8 13.2 8.3 5.0 9.3 31.9 12.0 15.4 12.4 19.8 3.6 25.2 15.4 10.6 6.1 10.4 15.3 8.8 18.0 27.4 32.5 31.4 19.1 21.6 18.6 10.9 23.2 18.7 13.2 12.3 72.3 42.6 0.4 12.0 29.3 23.8 52.3 35.2 23.2 22.8 25.4 20.9 0.6 27.7 26.2 22.1 4.4 3.6 19.8 63.2 25.1 30.1 27.5 11.6 15.3 2.2 21.3 30.2 30.9 8.4 2.2 29.7 37.6 22.6 12.7 79.8 13.2 31.2 54.8 29.7 15.6 43.7 17.7 13.9 52.7 19.0 0.8 14.2 24.4 25.8 22.1 13.3 7.6 5.2 9.5 24.4 3.1 16.9 47.1 1.5 8.7 0.8 1.1 0.8 0.7 0.9 1.3 0.4 0.9 1.2 1.1 1.7 4.3 0.7 0.5 4.5 0.6 13.6 12.9 12.3 11.1 14.2 17.1 13.2 19.4 15.7 15.4 25.2 18.0 13.0 12.8 20.4 101.9 8.8 32.6 42.7 11.1 8.0 42.2 23.7 16.5 7.8 8.6 14.6 7.3 22.9 2.0 12.1 25.8 50.9 13.7 0.9 9.6 24.1 16.0 13.8 0.8 96.6 14.5 0.7 18.8 18.8 11.9 0.0 17.4 8.9 15.0 21.3 50.5 135.8 28.7 14.2 2.8 21.5 1.0 9.9 10.7 10.6 60.0 2.5 9.3 0.0 447.8 59.7 22.1 24.1 9.4 7.0 16.4 35.2 20.9 15.7 25.7 19.7 38.2 20.6 2.9 2.1 13.9 32.5 1.6 26.5 47.7 41.8 33.2 CASP14 "MGC119078, MGC119079, MICE" ENSG00000105141 "Caspase 14" P31944 19 15049480-15058293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Hydrolase, Protease, Thiol protease" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "skin 1: 486.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 96.0" "Cancer enhanced" "Detected in many" "cervical cancer: 62.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "hTCEpi: 49.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010059, HPA027062" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3600000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" Mitochondria "CAB010059: AB_626800, HPA027062: AB_2672101" "unprognostic (1.17e-2)" "unprognostic (6.44e-3)" "unprognostic (6.22e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (9.42e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (5.96e-4)" "unprognostic (2.68e-1)" "unprognostic (4.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.97e-1)" 0.6 0.0 0.1 0.0 0.4 0.4 7.8 0.4 0.2 3.9 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.8 0.0 0.1 1.1 4.2 1.4 486.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.0 0.0 0.0 0.0 0.0 19.9 1.0 1.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.4 0.2 0.2 0.1 0.3 0.1 0.3 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 19.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 96.0 0.7 0.1 0.0 0.0 0.8 CBARP "BARP, C19orf26, DOS, MGC40084" ENSG00000099625 "CACN subunit beta associated regulatory protein" Q8N350 19 1228287-1238027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.3;pituitary gland: 22.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 21.8;Early spermatids: 55.9;Late spermatids: 97.4;Spermatocytes: 54.8" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012777 Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA012777: AB_2067005" "unprognostic (1.31e-1)" "unprognostic (4.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.10e-2)" "unprognostic (3.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.54e-5)" "unprognostic (3.48e-1)" "unprognostic (2.17e-1)" "unprognostic (4.58e-2)" "unprognostic (2.86e-3)" "unprognostic (3.03e-1)" "unprognostic (5.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.12e-1)" "unprognostic (2.40e-1)" "unprognostic (7.42e-5)" 1.4 2.6 6.0 0.1 9.8 0.0 0.4 2.0 15.3 0.7 0.0 0.6 0.1 0.5 0.0 1.4 0.5 0.1 1.7 12.3 3.1 2.3 0.3 1.0 0.0 5.6 1.3 4.9 0.4 0.0 22.3 0.1 1.3 0.8 0.0 0.3 0.4 0.1 0.4 3.1 0.2 0.0 0.0 0.1 0.4 1.7 1.8 0.0 0.6 0.0 0.0 0.3 0.9 0.0 0.3 0.4 1.1 3.1 0.1 0.5 0.4 2.7 0.8 0.5 0.5 1.1 0.1 0.0 2.7 0.5 0.3 0.9 0.4 0.6 0.1 0.5 0.7 0.1 1.1 0.9 1.4 0.0 1.0 0.6 0.2 0.6 0.1 0.5 0.4 0.5 1.7 0.0 0.3 2.3 0.0 0.6 1.6 0.1 1.2 2.0 0.4 0.2 0.1 0.2 1.4 4.2 0.0 0.0 3.1 0.1 0.4 0.5 1.2 0.7 2.6 2.3 0.7 0.1 0.2 0.0 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 9.8 2.0 15.3 12.3 3.1 5.6 1.3 1.3 0.0 1.8 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 1.2 21.8 1.7 1.8 0.0 1.5 0.0 0.0 2.1 0.0 0.6 0.0 1.9 0.1 55.9 0.9 2.2 0.7 0.0 0.0 0.0 0.2 0.1 1.2 1.1 1.6 0.0 0.9 1.4 0.1 0.3 3.3 0.0 0.0 0.0 0.8 0.0 97.4 1.8 1.2 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.9 0.0 0.2 0.0 1.7 0.0 0.7 1.4 54.8 7.0 1.1 0.0 0.0 0.3 0.1 0.0 0.3 CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 114.2;testis: 31.9" "Cell type enhanced" "Detected in some" "Early spermatids: 100.9;Late spermatids: 291.0;Spermatocytes: 61.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.5" "Region enriched" "Detected in all" 4 "cerebellum: 114.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "NTERA-2: 40.0;SCLC-21H: 126.0" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in many" 13 "cerebellum: 369.4" "Secreted in brain" NA NA 6000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.39e-2)" "unprognostic (1.88e-2)" "unprognostic (1.53e-1)" "unprognostic (3.16e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (9.65e-3)" "unprognostic (1.18e-2)" "unprognostic (6.31e-2)" "unprognostic (1.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.04e-2)" "unprognostic (7.68e-2)" "unprognostic (2.45e-1)" "unprognostic (1.06e-2)" "prognostic favorable (7.10e-4)" "unprognostic (1.60e-2)" 11.8 1.0 4.6 0.2 3.2 0.0 3.8 114.2 7.1 2.1 0.9 0.7 1.0 5.8 0.4 1.0 1.3 7.5 4.6 2.4 23.4 0.2 1.0 0.1 0.8 10.7 18.4 1.3 2.8 0.2 4.2 0.0 12.7 0.5 0.7 3.5 0.6 0.6 0.9 0.8 1.3 1.7 4.8 0.1 0.7 31.9 27.0 0.2 2.3 1.7 2.8 1.4 0.5 5.4 0.0 0.0 0.6 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 2.7 2.6 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 126.0 3.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.2 114.2 7.1 2.4 23.4 10.7 18.4 12.7 4.8 27.0 5.4 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.3 2.2 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 100.9 0.1 2.4 6.7 13.2 0.0 0.6 0.4 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 4.7 0.5 0.0 0.0 0.0 291.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.5 0.4 0.2 0.0 0.4 0.0 0.1 0.3 0.0 0.0 1.8 26.3 0.1 19.2 61.7 5.8 0.0 0.1 0.0 0.0 8.8 0.2 0.0 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 CCDC120 JM11 ENSG00000147144 "Coiled-coil domain containing 120" Q96HB5 X 49053572-49069857 "Cancer-related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;skin 1: 29.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 20.9;BEWO: 28.6;HaCaT: 19.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000561 Uncertain Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA000561: AB_2244190" "unprognostic (1.65e-1)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (7.59e-3)" "unprognostic (1.80e-3)" "unprognostic (1.08e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.72e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (4.85e-2)" "unprognostic (2.64e-2)" "unprognostic (3.82e-3)" "unprognostic (4.54e-3)" "unprognostic (2.34e-3)" 3.1 2.6 5.2 2.1 5.0 2.3 4.4 7.6 6.4 10.6 4.5 5.2 8.7 4.4 5.7 35.9 5.0 2.5 1.8 5.0 4.8 9.1 6.6 4.3 2.0 3.9 4.0 6.3 8.0 3.8 9.3 4.0 3.9 7.7 2.2 2.0 12.0 4.0 0.7 29.3 7.4 1.6 3.0 3.8 6.8 3.4 4.9 2.9 6.0 0.5 3.9 5.3 16.1 3.5 20.9 2.8 4.5 0.2 0.0 0.0 28.6 0.7 1.0 1.5 2.4 6.9 8.7 0.8 3.2 1.2 3.4 19.5 3.4 11.7 0.1 5.4 6.6 2.0 5.0 2.4 1.5 0.1 3.4 2.5 9.0 1.9 0.5 3.1 2.5 5.4 2.9 0.2 0.0 17.5 7.5 0.5 5.1 9.8 0.1 6.6 3.3 2.0 8.8 11.0 6.0 4.7 3.6 7.2 2.2 6.1 17.7 2.8 1.2 0.1 5.2 0.2 0.2 6.6 4.8 0.1 0.2 0.1 0.9 1.1 0.2 0.5 0.3 0.0 0.2 0.2 0.4 0.3 0.0 0.6 0.4 0.3 1.0 0.4 0.1 0.6 0.1 0.1 5.2 5.0 7.6 6.4 5.0 4.8 3.9 4.0 3.9 3.0 4.9 3.5 1.7 6.4 3.1 2.0 2.5 5.1 3.5 7.1 4.0 6.8 8.2 5.6 1.3 4.3 6.0 12.9 4.2 12.7 2.2 5.6 0.0 5.1 0.1 8.5 2.2 2.7 6.0 1.7 4.8 6.5 3.2 2.9 9.7 11.5 0.0 4.9 2.5 2.5 2.3 10.1 6.2 6.2 2.0 1.2 1.5 0.5 2.1 0.9 0.0 2.8 0.4 3.3 2.1 2.5 0.7 14.4 8.3 1.2 1.5 6.3 9.0 3.1 5.0 6.8 0.0 2.6 1.5 1.4 2.4 9.0 9.2 16.8 2.3 2.3 4.6 11.4 CCDC151 "MGC20983, ODA10" ENSG00000198003 "Coiled-coil domain containing 151" A5D8V7 19 11420604-11435782 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.0;parathyroid gland: 9.8;testis: 10.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Kupffer cells: 51.6;Muller glia cells: 58.9;Respiratory ciliated cells: 29.6;Spermatocytes: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.0;T-47d: 4.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA054626 Enhanced NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 5: Muller glia cells - Visual perception" "HPA054626: AB_2682547" "unprognostic (1.50e-1)" "unprognostic (6.59e-2)" "unprognostic (2.05e-3)" "unprognostic (4.41e-3)" "unprognostic (1.35e-2)" "unprognostic (6.30e-2)" "unprognostic (4.41e-3)" "unprognostic (2.32e-2)" "unprognostic (2.22e-1)" "unprognostic (5.09e-2)" "unprognostic (6.76e-4)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (4.27e-2)" "unprognostic (1.85e-1)" "unprognostic (2.35e-1)" "unprognostic (2.05e-1)" 0.4 2.8 4.6 0.0 4.6 0.0 0.4 4.7 6.5 1.6 15.0 0.3 0.0 0.6 0.3 0.2 8.5 0.0 1.9 5.0 4.7 3.5 0.7 2.3 0.0 6.4 6.8 0.6 0.4 9.8 7.0 0.4 5.7 0.8 0.0 0.9 1.7 0.5 0.1 0.5 0.2 0.0 5.2 2.6 0.4 10.4 4.6 0.0 2.9 0.0 0.0 0.3 0.8 4.9 0.2 0.0 0.6 0.2 0.1 0.2 0.5 0.2 0.1 0.3 0.4 0.0 0.0 0.1 0.2 0.1 1.2 0.1 0.5 0.2 0.0 0.5 0.5 0.2 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.5 0.1 0.4 0.0 0.1 0.2 0.1 1.0 0.2 0.0 0.7 0.3 0.0 2.0 1.3 0.6 0.1 0.1 0.1 4.8 0.2 0.0 0.8 0.1 1.7 0.0 1.7 1.4 0.1 1.8 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.6 4.6 4.7 6.5 5.0 4.7 6.4 6.8 5.7 5.2 4.6 4.9 1.1 0.0 0.0 6.5 5.7 0.9 0.7 1.0 0.6 1.1 0.8 1.3 2.2 1.5 2.6 12.9 0.0 0.5 0.0 0.0 29.4 0.2 12.4 20.3 4.2 2.9 0.0 0.0 2.3 0.2 0.5 3.8 0.5 1.1 4.5 1.6 14.3 1.2 4.7 1.7 1.7 0.5 2.0 51.6 1.7 14.5 2.8 7.8 7.2 1.0 2.6 58.9 0.0 1.0 0.8 0.1 0.0 0.7 0.8 0.1 0.1 1.1 29.6 3.2 6.6 15.2 6.8 22.7 6.6 0.1 0.4 1.2 1.5 1.0 0.0 0.5 CCDC24 MGC45441 ENSG00000159214 "Coiled-coil domain containing 24" Q8N4L8 1 43991359-43996528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 36.4;Respiratory ciliated cells: 57.6;Spermatocytes: 50.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 1.0;intermediate monocyte: 2.2;memory B-cell: 3.5;naive B-cell: 2.2;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 5 "B-cells: 3.5;granulocytes: 1.0;monocytes: 2.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA035424, HPA061710" Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Nucleoli, Cytosol" "HPA035424: AB_2674619, HPA061710: AB_2684591" "prognostic favorable (3.06e-5)" "unprognostic (1.47e-1)" "unprognostic (1.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.65e-2)" "prognostic favorable (3.18e-4)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.92e-2)" "unprognostic (6.38e-2)" "unprognostic (2.81e-1)" "unprognostic (7.00e-3)" "unprognostic (3.00e-1)" "unprognostic (1.74e-2)" "unprognostic (6.91e-2)" "unprognostic (1.51e-1)" "unprognostic (7.84e-2)" "unprognostic (2.15e-3)" 1.6 4.8 11.8 1.3 11.9 0.4 3.3 11.3 15.9 5.9 12.3 3.8 1.9 3.2 1.9 2.1 11.2 3.1 1.3 11.8 12.0 11.8 3.6 2.9 1.4 11.6 11.8 2.4 5.6 6.2 12.9 1.0 11.7 7.2 2.1 6.6 4.4 5.0 0.8 1.1 2.4 1.3 11.8 2.4 3.8 19.1 12.3 0.9 9.1 0.2 1.0 4.1 2.4 11.5 4.7 2.8 1.2 1.4 1.2 0.8 2.7 0.2 1.9 1.4 2.4 1.8 13.4 3.8 5.0 0.5 4.0 4.7 0.7 6.5 1.3 3.9 1.6 1.9 1.7 0.5 1.3 0.6 3.2 0.3 0.6 4.5 0.4 4.3 1.1 1.4 0.8 1.4 2.0 4.0 0.2 1.4 2.7 4.2 2.2 1.3 0.0 0.7 5.5 1.8 2.9 2.6 4.0 2.3 2.6 2.5 6.7 0.1 0.3 2.1 5.9 1.5 0.7 0.5 1.8 0.8 5.3 0.5 1.7 0.0 0.4 1.0 0.3 2.2 0.2 3.5 0.1 0.1 0.4 2.2 0.0 0.0 0.4 0.3 1.8 0.3 0.0 0.2 11.8 11.9 11.3 15.9 11.8 12.0 11.6 11.8 11.7 11.8 12.3 11.5 1.7 3.2 7.2 17.0 2.3 1.1 7.9 26.5 9.1 8.9 13.3 12.1 1.0 12.8 22.0 9.2 6.2 5.6 0.9 11.3 21.5 9.4 20.7 30.9 2.4 2.1 36.4 1.3 17.7 7.2 2.2 2.5 21.9 6.9 2.5 1.6 2.5 2.6 3.3 3.3 10.0 13.6 14.2 2.0 2.2 11.7 2.1 3.6 3.6 1.9 2.7 10.2 0.0 5.0 2.4 6.5 8.3 3.0 1.8 5.7 6.3 11.5 57.6 15.4 0.0 2.9 3.8 50.6 19.9 3.9 0.9 2.5 1.3 3.9 10.2 11.4 CCDC50 "C3orf6, DFNA44, Ymer" ENSG00000152492 "Coiled-coil domain containing 50" Q8IVM0 3 191329085-191398659 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 363.7;Oligodendrocyte precursor cells: 365.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 630.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 630.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001336 Approved Supported Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA001336: AB_1078421" "unprognostic (5.01e-2)" "unprognostic (1.44e-1)" "unprognostic (7.84e-2)" "unprognostic (8.77e-3)" "unprognostic (1.73e-2)" "unprognostic (8.29e-2)" "prognostic unfavorable (2.48e-5)" "unprognostic (3.03e-2)" "unprognostic (2.51e-2)" "unprognostic (4.48e-2)" "unprognostic (3.17e-3)" "unprognostic (2.05e-2)" "unprognostic (7.79e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-2)" "unprognostic (7.57e-2)" "unprognostic (4.19e-1)" 63.2 28.3 19.6 34.3 20.7 10.3 30.6 21.5 19.1 24.1 18.8 26.9 24.2 33.0 24.8 27.9 24.3 34.8 39.7 17.6 23.3 32.4 56.5 31.6 42.2 24.1 22.0 46.2 35.1 27.6 13.5 34.9 24.1 26.2 25.4 11.8 23.7 33.3 19.0 18.4 25.8 48.1 23.2 45.0 24.3 29.6 21.3 17.7 27.4 26.1 41.0 36.7 18.6 24.7 74.9 24.5 93.6 24.7 82.3 72.1 32.3 135.4 135.2 95.4 95.0 52.6 28.9 14.6 163.0 76.8 70.6 83.6 75.6 60.5 141.9 109.0 37.8 10.0 31.7 60.3 120.8 36.8 37.8 58.2 79.3 75.6 169.7 82.2 148.7 0.0 33.9 77.3 85.4 26.0 0.2 23.1 33.2 7.6 103.0 56.3 51.9 73.1 104.3 31.9 21.8 33.2 48.2 51.6 95.8 67.3 35.6 32.9 153.3 93.4 78.4 68.4 176.3 118.6 54.9 0.9 50.5 0.1 76.9 0.1 22.1 2.1 5.9 20.8 2.4 128.5 6.1 3.9 44.3 76.5 1.3 1.5 2.2 24.0 12.1 630.7 22.1 18.0 19.6 20.7 21.5 19.1 17.6 23.3 24.1 22.0 24.1 23.2 21.3 24.7 143.5 25.6 54.5 40.5 134.5 46.9 52.5 30.7 30.7 27.2 32.5 37.5 48.4 58.6 34.7 51.5 27.1 28.1 363.7 44.1 31.3 120.4 183.0 97.3 58.1 134.0 22.8 11.2 15.8 78.5 36.3 66.6 41.8 79.0 2.5 58.5 175.6 79.5 84.4 25.2 41.3 33.8 38.7 59.4 78.3 92.1 69.3 61.4 53.4 98.4 101.4 32.1 5.2 365.4 28.9 174.7 33.9 75.6 102.7 69.8 37.6 71.8 26.3 14.4 59.2 74.1 65.7 73.2 26.6 24.0 32.5 33.5 22.4 49.5 33.7 62.4 CCDC6 "D10S170, H4, PTC, TPC, TST1" ENSG00000108091 "Coiled-coil domain containing 6" Q16204 10 59788747-59906556 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019049, HPA019051" Enhanced Supported Cytosol No No 12000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "HPA019049: AB_1846163, HPA019051: AB_1846164" "unprognostic (1.88e-2)" "unprognostic (1.72e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-3)" "unprognostic (5.98e-3)" "prognostic favorable (5.48e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.39e-2)" "unprognostic (2.45e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.95e-4)" "unprognostic (4.08e-1)" "unprognostic (4.69e-2)" "unprognostic (2.23e-1)" "unprognostic (2.56e-1)" "unprognostic (9.95e-2)" "unprognostic (4.19e-2)" 11.9 12.2 21.1 13.9 23.4 16.8 22.4 10.2 20.0 23.4 8.5 23.5 22.8 24.9 16.7 34.1 25.3 16.7 10.0 24.9 21.4 21.2 12.1 17.3 21.4 12.4 15.8 15.7 25.2 17.9 11.5 13.2 17.4 19.4 19.8 18.3 29.0 14.3 17.3 28.6 16.2 30.8 11.9 14.7 18.6 11.4 20.8 12.1 18.3 12.2 21.6 17.3 23.1 12.6 42.9 38.0 18.7 41.9 27.8 41.6 37.9 20.6 27.2 20.2 23.7 74.4 81.8 36.5 30.2 34.6 11.7 61.7 37.7 37.5 30.0 55.1 18.7 29.8 29.1 45.5 33.5 34.5 26.9 30.3 48.7 33.7 81.8 28.3 30.2 20.4 22.6 22.7 26.6 57.6 14.5 19.8 29.9 40.1 25.6 19.2 30.5 23.0 33.9 36.2 19.0 16.6 26.1 107.8 23.1 24.1 68.7 18.4 31.1 18.8 33.9 29.3 34.9 12.0 14.9 16.3 29.6 64.6 11.9 0.0 2.0 0.0 1.0 2.3 1.1 4.3 1.5 1.3 5.0 4.9 1.3 1.0 0.1 0.8 1.3 1.3 1.4 1.0 21.1 23.4 10.2 20.0 24.9 21.4 12.4 15.8 17.4 11.9 20.8 12.6 24.0 99.3 25.9 45.1 41.6 95.0 51.7 25.3 70.0 15.1 51.2 38.7 16.5 28.6 46.3 25.8 41.7 37.8 31.4 42.6 29.4 50.2 27.6 105.2 54.6 22.4 27.0 25.7 83.2 65.3 18.8 27.8 39.8 134.5 29.1 45.2 17.2 20.1 23.1 16.8 58.4 38.9 30.5 40.7 35.3 80.6 24.5 36.4 16.0 32.8 23.0 11.5 13.4 55.3 34.2 50.2 25.0 19.5 26.4 52.2 47.1 48.4 28.1 49.8 19.7 31.4 27.0 2.3 22.4 92.3 80.1 27.0 24.3 32.5 46.3 46.1 CCDC68 SE57-1 ENSG00000166510 "Coiled-coil domain containing 68" Q9H2F9 18 54901509-54959461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.8;placenta: 32.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 95.2;Early spermatids: 95.4;Pancreatic endocrine cells: 87.9;Paneth cells: 68.7;Proximal enterocytes: 61.1" "Cancer enhanced" "Detected in many" "stomach cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 10.8;HHSteC: 13.6;HSkMC: 14.9;RT4: 10.5;TIME: 28.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA040865, HPA048197" Supported Approved "Golgi apparatus,Cytosol" No NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Cytosol "HPA040865: AB_2677176, HPA048197: AB_2680310" "unprognostic (1.36e-2)" "prognostic unfavorable (4.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.38e-2)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (2.65e-2)" "unprognostic (6.29e-2)" "unprognostic (2.71e-1)" "unprognostic (1.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.77e-2)" "unprognostic (9.71e-2)" "unprognostic (6.12e-2)" "unprognostic (2.38e-1)" 5.5 3.8 1.6 4.1 1.5 0.4 3.4 1.4 2.7 4.2 2.3 18.9 20.2 3.3 0.8 1.8 2.4 5.1 5.7 1.5 3.6 2.8 9.5 13.0 0.8 2.0 2.3 15.7 2.8 0.8 3.6 32.4 2.0 4.2 18.2 0.6 1.8 1.3 1.5 0.9 24.8 2.7 1.2 7.2 14.3 8.8 3.3 0.6 2.6 4.4 1.3 2.3 1.8 1.3 10.8 3.3 0.0 0.0 3.0 8.3 0.0 0.3 4.2 0.6 0.7 5.9 6.2 0.0 7.6 0.0 0.1 0.1 0.7 6.8 0.5 0.0 1.6 0.8 3.6 1.2 13.6 0.0 0.0 14.9 0.0 3.2 0.1 0.0 4.9 0.0 0.0 0.1 0.4 0.8 0.0 0.2 0.0 7.6 3.6 0.3 0.0 0.3 1.2 10.5 0.1 2.5 3.3 1.0 0.1 1.2 0.0 0.0 28.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.6 1.5 1.4 2.7 1.5 3.6 2.0 2.3 2.0 1.2 3.3 1.3 38.5 19.2 10.3 0.3 1.0 0.3 7.4 4.8 1.2 0.1 2.0 1.9 5.5 10.0 13.3 1.8 0.0 2.3 0.3 95.2 1.9 7.2 95.4 15.0 2.5 40.8 6.0 3.6 5.7 35.6 2.7 9.6 38.2 27.1 8.8 2.6 37.5 7.0 0.4 0.0 0.5 21.8 8.2 3.2 1.3 36.7 3.4 0.6 0.0 12.2 1.0 3.3 1.0 0.0 0.1 87.9 68.7 0.7 0.0 32.4 61.1 5.3 4.2 0.2 6.6 0.9 3.0 1.2 2.2 1.1 0.0 6.0 0.4 3.8 20.2 6.4 CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 351.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;dendritic cells: 106.9;Granulosa cells: 138.2;NK-cells: 197.8;Plasma cells: 133.6;Theca cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 129.2;Daudi: 199.9;U-266/70: 120.5;U-698: 119.1" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 108.9 89.6 6.7 45.8 8.4 46.3 60.5 12.2 7.9 15.2 13.4 138.5 19.6 32.9 13.3 54.1 37.1 19.3 96.9 5.9 8.9 10.7 24.0 39.0 70.4 13.3 13.8 27.1 47.5 32.1 8.5 14.8 13.6 23.0 20.5 1.8 14.4 29.4 351.9 13.3 44.7 45.6 11.3 55.4 37.0 13.2 9.2 37.8 11.6 163.8 66.8 87.7 21.9 7.2 8.0 1.6 0.4 6.4 129.2 13.1 4.2 1.5 13.1 2.6 2.4 2.1 1.1 199.9 6.3 0.5 3.3 1.0 3.0 2.8 0.9 0.1 2.7 27.0 0.0 17.5 21.1 9.9 34.4 33.0 0.2 1.0 0.0 2.5 13.1 0.0 23.7 44.0 0.1 0.6 43.8 23.3 7.5 0.1 15.2 36.0 1.0 12.1 0.5 5.9 0.2 0.8 2.4 3.2 1.7 3.2 2.0 24.0 32.0 1.0 6.1 0.6 1.5 120.5 60.1 119.1 1.4 22.2 0.0 30.9 12.4 13.5 11.3 10.9 10.3 5.4 8.8 10.8 10.0 10.4 6.1 6.6 9.6 14.3 10.3 19.3 8.5 11.5 6.7 8.4 12.2 7.9 5.9 8.9 13.3 13.8 13.6 11.3 9.2 7.2 51.0 12.8 78.4 0.7 68.8 2.5 3.0 3.5 1.2 0.4 4.8 2.4 124.5 1.5 13.5 1.8 0.0 7.3 106.9 0.2 0.0 2.9 0.5 26.8 2.7 58.9 1.8 32.2 1.8 20.0 9.6 18.4 7.1 1.3 34.8 138.2 28.2 39.7 7.3 6.7 2.7 0.0 4.1 64.0 12.2 2.4 5.6 46.5 10.6 11.2 73.5 4.9 197.8 1.0 0.6 8.8 0.1 7.9 133.6 3.6 4.5 3.2 51.3 1.4 13.1 4.7 14.8 1.2 1.0 0.7 1.3 35.4 65.7 132.1 0.9 23.5 CCDC96 FLJ90575 ENSG00000173013 "Coiled-coil domain containing 96" Q2M329 4 7040849-7043001 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 65.4" "Cell type enhanced" "Detected in many" "Early spermatids: 76.7;Endometrial ciliated cells: 59.7;Late spermatids: 93.4;Respiratory ciliated cells: 53.4;Spermatocytes: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 5.3" HPA047546 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA047546: AB_2680082" "unprognostic (6.20e-3)" "unprognostic (4.03e-2)" "unprognostic (7.95e-2)" "prognostic favorable (4.05e-4)" "unprognostic (1.22e-2)" "unprognostic (3.51e-3)" "unprognostic (1.77e-1)" "unprognostic (9.24e-3)" "unprognostic (1.01e-2)" "unprognostic (3.92e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.43e-1)" "prognostic favorable (3.80e-5)" "unprognostic (4.37e-2)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (1.10e-2)" 0.8 2.0 2.0 0.5 2.4 1.3 1.2 2.4 2.1 1.1 6.0 0.8 0.9 0.8 0.7 1.3 10.7 0.8 0.6 2.5 2.1 1.4 0.5 1.7 0.8 3.4 3.7 0.7 1.3 1.0 3.3 0.5 3.0 1.0 0.6 1.8 1.0 1.1 1.1 1.7 0.8 0.6 2.7 0.8 1.1 65.4 2.6 0.7 1.5 0.7 0.6 0.7 0.9 1.9 1.0 2.7 1.4 1.1 1.8 1.2 0.3 2.7 1.6 3.0 1.8 0.9 2.4 0.6 0.7 1.5 3.9 1.2 0.5 1.2 0.9 0.1 0.4 0.6 1.1 0.7 0.9 0.8 1.5 1.1 1.3 1.8 0.2 0.3 1.2 1.9 0.4 0.2 1.9 2.4 1.6 1.0 0.5 0.9 1.6 0.6 0.9 0.1 5.3 1.0 3.8 0.8 2.2 1.0 0.5 1.3 1.0 1.5 1.3 2.5 0.7 1.5 2.1 0.0 0.1 0.5 1.9 0.0 0.8 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.1 0.0 0.5 0.0 0.0 0.5 0.1 0.1 1.0 0.0 0.0 0.1 2.0 2.4 2.4 2.1 2.5 2.1 3.4 3.7 3.0 2.7 2.6 1.9 3.1 0.0 4.8 0.0 1.0 0.6 0.8 2.8 0.6 4.0 3.7 3.2 0.9 0.0 6.9 3.7 12.5 0.6 0.7 2.5 1.9 2.2 76.7 59.7 4.0 2.3 5.4 0.0 0.0 1.1 0.6 1.5 0.5 2.4 0.0 0.6 2.9 0.9 1.2 0.0 0.0 1.9 4.1 2.2 0.9 93.4 3.1 1.7 1.8 0.0 1.1 6.9 0.0 0.0 0.0 1.7 2.7 4.1 0.1 1.2 0.2 4.5 53.4 19.6 0.0 4.6 2.3 30.6 3.6 1.2 1.0 0.5 0.8 2.7 0.8 0.9 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCL17 "ABCD-2, SCYA17, TARC" ENSG00000102970 "C-C motif chemokine ligand 17" Q92583 16 57404767-57416063 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 21.1" "Cell type enriched" "Detected in some" 55 "monocytes: 12161.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 640 "HDLM-2: 2395.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "basal ganglia: 4.3" CAB002583 Uncertain "Secreted to blood" NA NA 248000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB002583: AB_564022" "unprognostic (4.62e-3)" "prognostic favorable (1.91e-5)" "unprognostic (5.83e-2)" "unprognostic (3.52e-4)" "unprognostic (4.51e-2)" "unprognostic (1.78e-3)" "unprognostic (4.44e-1)" "unprognostic (3.41e-2)" "unprognostic (6.36e-2)" "unprognostic (4.28e-2)" "unprognostic (4.11e-1)" "unprognostic (2.91e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-1)" "unprognostic (7.72e-3)" "unprognostic (4.14e-3)" "prognostic favorable (5.80e-4)" 1.2 0.1 0.1 8.3 0.1 0.0 1.9 0.1 0.4 1.4 0.0 1.5 0.1 0.0 0.0 3.1 0.6 2.9 1.3 0.2 0.0 0.6 0.3 4.5 8.4 0.1 0.0 0.2 0.5 0.1 0.0 0.1 0.1 0.3 2.7 0.0 2.5 0.2 0.1 2.4 3.7 2.6 0.0 0.8 0.7 0.5 0.1 21.1 0.8 0.2 5.7 3.4 0.9 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 3.3 0.0 0.0 0.0 2395.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.0 3.7 0.2 0.0 0.0 2.9 1.5 0.1 0.1 2.0 0.0 0.0 0.1 0.0 1.0 0.0 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.0 5.1 0.0 0.4 10.8 0.1 3.4 0.0 0.0 1.1 1.5 0.0 0.0 3.8 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.3 0.1 0.0 0.6 0.0 0.0 0.2 37.4 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 2.0 1.0 217.9 0.3 0.0 48.7 0.0 0.0 12161.5 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.1 0.0 0.4 2.1 0.0 0.0 0.0 12.0 0.0 0.5 0.0 2.7 0.0 0.4 0.0 0.0 0.7 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 8 "dendritic cells: 2049.9;NK-cells: 2344.0;T-cells: 1947.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Cell line enhanced" "Detected in some" "HL-60: 94.1;NB-4: 539.9;THP-1: 139.9;U-937: 120.1" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 17.2 17.1 3.9 36.3 4.0 122.1 19.5 3.8 6.5 15.5 5.4 27.7 48.7 15.7 14.4 15.8 14.0 42.9 8.9 3.9 3.7 7.5 28.4 57.4 135.2 7.3 4.3 16.9 7.0 3.0 3.8 6.3 6.4 10.4 25.6 0.3 33.5 7.9 4.8 4.0 84.5 10.5 5.8 123.9 47.9 4.6 4.7 29.5 11.5 2.7 33.4 31.4 9.5 6.1 0.7 0.5 0.2 0.0 0.5 0.4 0.8 0.3 4.0 17.8 20.8 0.4 1.7 0.3 1.6 0.9 1.3 0.9 0.0 0.0 2.3 6.5 0.3 0.0 1.5 0.6 0.5 94.1 0.8 0.1 0.2 5.5 0.3 0.0 0.2 0.1 0.1 12.5 0.2 0.6 0.1 539.9 0.5 0.0 0.0 0.6 0.2 14.0 0.2 0.5 0.1 0.5 0.2 1.2 13.4 0.5 0.2 139.9 0.3 0.6 0.3 0.6 0.4 14.2 6.6 0.8 0.4 120.1 1.3 657.8 30.0 35.8 6788.6 21.3 4221.0 61.3 1394.5 7164.3 49.8 41.6 332.4 4032.4 189.9 2041.1 26.1 46.5 25.9 6664.4 3.9 4.0 3.8 6.5 3.9 3.7 7.3 4.3 6.4 5.8 4.7 6.1 22.4 99.3 244.4 0.3 55.2 7.4 1.3 6.0 4.6 1.3 19.9 18.2 5.4 21.5 41.7 1.8 0.0 1.8 2049.9 3.1 1.9 6.3 1.2 5.5 5.4 24.2 1.8 106.3 0.5 0.2 7.1 26.0 46.9 6.7 80.8 0.2 45.0 7.0 33.8 0.0 0.3 3.5 0.0 48.0 25.0 0.1 0.3 256.3 12.4 2.8 38.5 0.4 2344.0 0.0 0.4 1.6 6.9 0.4 179.5 1.7 2.4 6.7 29.2 1.1 0.0 6.5 28.2 1.1 1.2 5.5 6.3 16.0 1947.0 0.1 3.5 1.9 CCM2L "C20orf160, dJ310O13.5" ENSG00000101331 "CCM2 like scaffold protein" Q9NUG4 20 32010438-32032180 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 141.6" "Cell type enriched" "Detected in some" 5 "Theca cells: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.2;HUVEC TERT2: 9.0;NTERA-2: 4.6;RH-30: 3.2;SCLC-21H: 7.7;TIME: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008434, HPA071063" Uncertain Supported Nucleoplasm NA NA "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA008434: AB_1845671, HPA071063: AB_2686339" "unprognostic (1.71e-1)" "unprognostic (4.64e-2)" "unprognostic (2.43e-3)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (1.27e-3)" "unprognostic (2.37e-1)" "unprognostic (2.04e-1)" "unprognostic (4.34e-2)" "unprognostic (1.00e-3)" "unprognostic (7.84e-2)" "unprognostic (4.66e-3)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" 15.9 5.4 7.2 1.6 7.3 0.0 15.0 9.5 6.8 8.7 4.2 4.6 1.3 8.9 0.6 3.7 7.7 2.5 23.2 6.1 5.8 13.3 2.2 11.8 1.5 6.8 6.4 3.6 2.6 1.4 4.1 7.8 7.0 5.8 1.1 0.4 3.4 1.8 4.8 3.9 5.4 3.3 6.1 141.6 4.2 1.6 7.3 0.8 10.2 4.8 0.9 6.4 6.3 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 9.0 0.9 0.0 0.0 0.0 2.4 0.0 0.0 4.6 0.1 0.0 0.6 3.2 0.1 0.0 0.0 7.7 0.9 0.2 0.0 0.0 1.1 2.5 0.0 4.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 7.3 9.5 6.8 6.1 5.8 6.8 6.4 7.0 6.1 7.3 5.2 45.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.5 0.6 4.6 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.2 32.1 0.0 0.0 2.9 0.2 0.0 1.0 0.0 0.2 0.0 4.3 24.3 0.0 0.0 3.3 2.4 0.0 0.0 0.3 0.3 0.4 0.0 0.2 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 1.8 0.3 0.6 0.1 0.3 0.0 0.1 248.7 0.0 0.1 CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.5" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 81.2;Hofbauer cells: 117.4;Kupffer cells: 171.9;Macrophages: 74.2;monocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 330.3;RPMI-8226: 158.5;U-266/70: 57.7;U-266/84: 183.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" 21.0 4.7 2.1 42.5 2.3 24.8 4.0 2.4 3.1 2.5 2.6 5.6 7.3 2.5 1.6 3.4 2.8 11.7 2.4 1.9 2.6 4.9 17.2 18.7 10.9 5.2 3.2 2.1 3.1 1.9 0.9 26.4 4.5 1.6 7.3 0.3 2.1 2.6 1.3 0.6 6.6 15.5 4.7 30.8 4.9 1.7 4.9 5.7 1.0 3.3 10.2 16.7 0.7 7.4 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.3 0.7 1.5 0.1 0.4 0.0 3.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 6.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 330.3 0.0 0.2 0.2 13.0 0.0 0.0 0.0 0.1 0.0 158.5 0.0 5.6 0.0 0.0 0.0 0.4 1.3 0.9 0.2 35.5 0.0 0.8 0.0 0.0 0.2 57.7 183.7 0.1 29.1 26.5 0.4 82.5 125.1 25.8 10.5 76.2 50.1 2.9 0.1 8.5 53.9 0.2 0.1 1.4 113.4 84.5 51.3 18.9 0.1 50.6 2.1 2.3 2.4 3.1 1.9 2.6 5.2 3.2 4.5 4.7 4.9 7.4 0.3 3.2 3.0 0.0 2.0 0.9 0.0 0.0 0.6 0.0 0.1 0.5 0.6 0.0 1.3 0.0 0.0 1.3 15.9 0.0 1.9 0.0 0.4 0.1 0.6 1.6 0.0 1.7 0.0 0.0 81.2 2.4 0.0 0.0 3.8 0.0 1.4 1.2 117.4 0.0 0.0 0.0 0.0 171.9 23.5 0.1 0.0 74.2 5.4 9.4 51.5 0.2 7.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 3.2 1.5 0.2 0.0 0.4 0.5 0.0 0.2 0.2 1.7 2.9 6.0 0.0 0.0 0.0 CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951644-32956349 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.0;urinary bladder: 5.4" "Cell type enhanced" "Detected in some" "granulocytes: 2.5;Horizontal cells: 5.0;Plasma cells: 2.1;Spermatogonia: 1.8;T-cells: 7.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "T-reg: 60.9" "Lineage enriched" "Detected in many" 41 "T-cells: 60.9" "Cell line enriched" "Detected in some" 17 "HDLM-2: 206.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031613 Approved Supported "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA031613: AB_10601096" "unprognostic (4.63e-3)" "unprognostic (8.70e-3)" "unprognostic (2.82e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (4.59e-7)" "unprognostic (3.02e-1)" "unprognostic (5.05e-3)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (5.53e-4)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" 0.5 0.2 0.3 8.6 0.3 1.7 0.6 0.8 0.7 0.6 0.2 0.9 0.6 0.4 0.3 1.2 0.2 3.3 0.2 0.4 0.4 0.3 0.6 1.7 7.0 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.4 0.8 1.2 0.1 0.5 0.1 2.0 2.1 1.5 0.6 0.0 3.2 1.4 0.8 0.2 13.0 0.3 0.1 8.0 5.4 0.2 0.7 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 206.5 0.0 12.2 0.7 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.2 0.0 5.8 3.2 0.8 0.0 0.0 1.8 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.5 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.2 0.1 0.2 0.2 0.2 0.0 1.4 0.3 0.3 0.4 0.3 0.4 0.3 11.5 3.4 0.1 0.4 0.3 0.3 1.1 0.3 0.3 0.4 60.9 1.7 0.3 0.3 0.8 0.7 0.4 0.4 0.2 0.1 0.4 0.0 0.2 0.7 0.1 0.0 0.6 0.0 0.4 0.4 0.7 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.5 0.0 0.4 0.1 0.1 5.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.7 0.8 0.0 0.5 0.2 0.0 1.8 0.0 0.1 0.0 7.8 0.0 0.0 0.6 CCR5 "CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22" ENSG00000160791 "C-C motif chemokine receptor 5" P51681 3 46370854-46376206 "CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "Kupffer cells: 5.5;Langerhans cells: 32.6;Macrophages: 12.8;T-cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 39.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "JURKAT: 1.4;Karpas-707: 6.8;U-266/84: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (4.32e-3)" "unprognostic (1.94e-3)" "unprognostic (1.89e-3)" "prognostic favorable (7.42e-5)" "unprognostic (1.80e-2)" "prognostic favorable (9.33e-5)" "unprognostic (3.38e-3)" "unprognostic (9.90e-3)" "unprognostic (7.65e-2)" "unprognostic (6.22e-2)" "unprognostic (1.36e-1)" "unprognostic (5.34e-2)" "unprognostic (1.14e-3)" "unprognostic (8.34e-2)" "unprognostic (4.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.42e-2)" 1.8 2.0 0.5 15.0 0.6 1.3 2.4 0.6 0.7 2.1 1.0 3.3 4.1 1.4 1.0 1.4 1.7 5.0 1.1 0.4 0.8 1.0 3.4 7.4 14.4 1.6 0.9 1.7 0.6 0.6 0.4 0.7 1.3 1.9 3.9 0.1 2.9 1.0 0.3 1.1 5.8 3.2 1.2 9.4 6.8 0.8 1.2 4.2 0.8 0.2 9.4 4.8 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 6.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 3.1 0.0 0.0 0.1 0.0 12.0 2.2 0.0 11.0 3.8 39.7 0.5 4.7 16.1 9.5 0.0 0.4 4.1 0.5 6.3 0.0 9.0 8.0 3.2 0.5 0.6 0.6 0.7 0.4 0.8 1.6 0.9 1.3 1.2 1.2 2.4 0.3 0.0 1.7 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.3 1.5 0.0 1.3 0.0 1.4 0.3 4.7 0.0 0.0 0.0 0.0 5.5 32.6 0.0 0.0 12.8 3.6 1.9 1.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 13.1 0.1 0.0 0.1 CD1C CD1 ENSG00000158481 "CD1c molecule" P29017 1 158289923-158294774 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 130.4" "Cell type enriched" "Detected in some" 6 "Langerhans cells: 551.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 84.1;myeloid DC: 324.9" "Group enriched" "Detected in many" 8 "B-cells: 84.1;dendritic cells: 324.9" "Group enriched" "Detected in some" 10 "JURKAT: 14.8;MOLT-4: 49.4" HPA068359 Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA 200000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "Endoplasmic reticulum" "HPA068359: " "unprognostic (2.55e-3)" "prognostic favorable (1.79e-5)" "unprognostic (1.75e-5)" "unprognostic (3.09e-5)" "unprognostic (3.12e-2)" "unprognostic (8.13e-3)" "unprognostic (2.01e-1)" "unprognostic (3.80e-3)" "unprognostic (7.11e-3)" "unprognostic (1.87e-1)" "unprognostic (7.41e-2)" "unprognostic (1.93e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (8.05e-2)" "unprognostic (1.99e-1)" 2.7 0.8 0.0 17.3 0.0 1.1 5.0 0.0 0.2 2.3 0.0 3.4 2.0 2.4 0.6 4.5 1.8 7.7 2.0 0.0 0.0 1.2 4.1 6.5 26.2 0.0 0.0 0.9 0.7 0.6 0.2 0.1 0.0 1.8 9.4 0.0 2.8 1.3 1.0 12.2 12.0 3.1 0.0 23.0 3.7 0.9 0.0 130.4 0.7 1.1 38.2 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 49.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.9 0.0 0.6 26.8 0.1 0.1 24.7 0.3 84.1 0.1 0.0 324.9 49.1 0.2 0.0 1.1 4.1 3.7 1.5 0.5 15.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.2 0.0 26.6 13.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 4.1 0.0 0.1 1.5 0.0 0.8 0.0 0.0 0.1 1.4 0.0 0.0 3.8 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 7.1 551.4 4.5 0.0 91.2 19.6 0.0 11.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.5 0.0 0.0 0.2 0.4 0.1 0.3 0.0 7.4 0.0 1.9 0.0 0.0 0.0 CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 155.4;Fibroblasts: 166.9;Leydig cells: 74.9;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Cell line enhanced" "Detected in many" "ASC diff: 492.4;ASC TERT1: 481.9;BJ: 222.2;BJ hTERT+: 330.1;fHDF/TERT166: 451.1;HSkMC: 516.8;U-2197: 794.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" 237.3 12.9 2.3 39.3 2.4 0.4 155.5 2.2 4.0 87.2 1.5 31.7 7.8 52.2 6.9 19.6 60.8 32.3 30.3 2.2 2.2 18.7 3.6 36.5 6.2 2.4 2.6 23.9 11.7 3.3 8.8 67.4 2.2 17.8 7.4 0.4 18.2 19.4 15.8 51.0 27.2 26.5 2.0 7.2 26.3 5.0 3.9 5.3 35.0 6.5 2.6 63.4 61.5 2.0 0.0 0.0 4.9 0.0 492.4 481.9 0.3 222.2 330.1 16.3 15.1 0.1 0.0 0.0 5.8 451.1 0.0 0.0 0.2 0.2 3.5 0.0 0.0 0.0 0.1 3.3 97.5 0.0 0.0 516.8 0.0 21.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.4 3.2 2.5 0.0 1.4 9.5 0.0 0.2 0.0 0.0 2.8 7.6 0.0 1.2 0.0 13.4 0.5 0.4 0.1 0.0 0.8 794.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 2.6 0.0 0.1 3.1 21.8 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.4 2.2 4.0 2.2 2.2 2.4 2.6 2.2 2.0 3.9 2.0 15.0 0.0 0.0 1.3 1.3 12.5 0.0 0.0 0.6 0.1 1.2 1.5 2.2 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.3 5.3 155.4 5.8 0.0 0.0 0.0 0.0 2.5 166.9 13.3 3.1 0.0 0.0 2.5 0.0 6.0 0.0 0.0 0.0 0.0 0.3 14.4 2.3 74.9 1.6 12.4 1.9 0.6 2.9 1.0 0.0 0.0 0.3 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.1 32.9 5.5 59.3 0.1 0.1 0.8 8.2 4.4 6.9 1.1 0.0 0.1 CD28 ENSG00000178562 "CD28 molecule" P10747 2 203706475-203738912 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 30.8;placenta: 14.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 34.1;T-cells: 52.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 101.9" "Lineage enriched" "Detected in many" 7 "T-cells: 101.9" "Group enriched" "Detected in some" 14 "Karpas-707: 360.6;RPMI-8226: 173.2;U-266/70: 294.1;U-266/84: 283.7" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Not detected" "Not detected" HPA070003 Enhanced NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA070003: AB_2686226" "unprognostic (5.54e-2)" "unprognostic (2.16e-4)" "unprognostic (1.90e-3)" "unprognostic (2.49e-3)" "unprognostic (3.44e-2)" "unprognostic (6.07e-5)" "unprognostic (9.09e-2)" "unprognostic (4.66e-2)" "unprognostic (3.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-1)" "unprognostic (1.68e-1)" "unprognostic (5.78e-5)" "unprognostic (4.77e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (8.96e-2)" 4.0 0.3 0.0 14.9 0.1 3.3 0.8 0.1 0.1 1.1 0.9 1.7 1.1 0.7 0.3 0.9 0.5 4.1 0.6 0.1 0.1 0.5 1.3 1.9 28.0 0.1 0.0 0.3 0.5 0.2 0.1 14.8 0.1 1.0 1.9 0.1 0.6 0.8 0.3 0.3 3.0 1.4 0.1 7.2 2.5 0.7 0.2 30.8 0.5 0.1 18.6 4.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.7 2.0 0.0 360.6 0.2 0.0 19.9 0.0 0.1 0.0 0.0 0.1 0.3 173.2 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.1 0.3 294.1 283.7 2.9 0.3 0.1 0.0 1.7 0.6 1.0 8.3 0.5 50.6 0.3 54.5 26.1 0.1 0.3 48.1 18.6 13.8 0.2 0.5 0.2 101.9 14.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.5 0.0 1.3 0.0 2.4 2.9 0.1 0.0 0.6 0.0 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.2 3.2 0.1 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.3 1.0 2.0 0.1 1.3 0.0 0.0 0.1 34.1 0.0 0.0 0.0 0.0 0.8 5.3 0.2 0.0 4.4 0.0 1.0 1.5 0.0 2.1 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.2 1.6 0.1 52.6 0.0 0.0 0.0 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 504.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 999.7;Ductal cells: 992.1;Exocrine glandular cells: 869.6;Langerhans cells: 1934.2;Suprabasal keratinocytes: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1650.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 1200000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" 143.7 42.4 29.2 218.0 33.9 308.1 164.7 63.0 25.1 146.0 16.8 91.1 53.0 200.4 20.1 227.8 69.0 129.7 30.4 33.0 116.5 31.3 31.0 214.1 108.8 114.9 102.3 11.7 263.2 6.0 8.1 74.1 118.3 87.3 111.5 38.0 504.2 57.0 17.1 433.3 60.8 175.8 114.3 83.8 61.5 6.6 62.8 64.2 76.2 27.7 188.7 235.2 193.4 114.9 493.0 448.6 4.3 1.2 252.6 691.5 1.6 962.2 740.3 521.3 288.2 30.4 150.4 0.7 126.5 1350.2 1065.4 820.1 9.9 1013.9 716.4 110.3 6.2 18.9 198.3 0.3 262.3 254.6 1124.3 315.4 778.3 693.2 552.7 1650.0 184.3 0.1 4.0 157.9 518.9 3.0 25.6 166.9 9.8 8.7 136.4 1.4 89.3 7.5 777.4 138.1 2.0 1.4 185.2 5.5 462.8 38.6 25.7 15.1 547.3 646.6 120.0 815.8 1006.0 281.6 327.7 3.7 980.4 145.1 969.8 127.4 403.0 35.4 140.6 257.8 196.5 122.5 210.1 186.5 229.0 90.0 179.7 153.6 92.6 322.3 356.1 79.9 309.7 437.3 29.2 33.9 63.0 25.1 33.0 116.5 114.9 102.3 118.3 114.3 62.8 114.9 41.0 96.1 361.8 54.5 250.1 999.7 297.7 335.3 228.2 0.6 139.6 71.2 8.6 27.1 125.6 20.2 2.1 4.5 257.0 14.0 1.9 992.1 41.3 43.6 395.4 50.9 100.1 94.4 0.4 869.6 3.6 282.2 39.8 196.9 763.2 25.2 13.2 3.6 226.6 0.0 0.4 93.3 30.5 474.3 1934.2 24.3 22.4 523.9 604.7 8.4 594.2 29.6 62.8 0.5 11.2 813.1 10.9 0.4 216.3 386.7 6.0 1.6 18.8 2.0 157.8 197.2 227.9 0.4 0.4 279.3 1024.9 17.9 430.8 1.0 79.1 330.7 CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 148.4;lymphoid tissue: 283.9" "Cell type enhanced" "Detected in many" "B-cells: 336.1;dendritic cells: 251.2;Kupffer cells: 245.8;Macrophages: 218.3;monocytes: 366.6;NK-cells: 454.2;T-cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 220.9;HMC-1: 236.9;U-266/70: 501.4;U-266/84: 360.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 2000000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" 11.8 5.9 1.4 115.3 1.5 148.4 18.8 1.5 4.7 10.2 2.3 24.9 20.5 6.7 5.0 8.4 5.7 26.6 4.3 1.3 1.7 4.4 19.9 31.0 283.9 2.6 1.8 3.1 2.0 1.6 1.6 5.8 2.7 8.1 32.5 0.1 14.0 4.4 2.9 3.5 48.3 12.5 2.1 160.0 32.5 2.9 3.2 138.9 5.2 3.4 256.8 41.8 4.5 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 220.9 0.1 0.0 0.0 0.5 0.1 0.0 0.0 6.0 0.0 2.1 0.0 0.0 0.0 27.1 236.9 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.4 78.6 0.0 0.0 78.9 38.4 0.1 0.0 0.0 4.7 0.1 34.3 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.3 0.2 0.4 501.4 360.3 89.9 0.2 66.7 0.1 218.1 327.1 230.8 242.8 470.2 335.8 206.2 275.2 283.4 329.7 161.2 277.9 301.6 82.1 160.7 487.4 57.0 229.9 603.5 1.4 1.5 1.5 4.7 1.3 1.7 2.6 1.8 2.7 2.1 3.2 4.1 3.7 0.0 9.6 0.7 336.1 5.5 0.8 0.0 1.8 0.0 2.0 1.7 1.1 2.8 1.3 3.7 0.0 0.6 251.2 0.1 1.9 0.2 0.1 0.7 0.5 2.8 1.2 21.5 0.1 0.2 0.8 2.4 6.6 0.6 90.7 0.1 7.1 2.0 86.4 0.0 0.1 0.1 0.0 245.8 106.5 0.5 1.8 218.3 39.2 1.0 366.6 0.0 454.2 0.5 0.0 0.1 0.0 0.4 127.4 0.4 0.0 4.9 2.2 0.0 0.0 1.7 2.1 0.5 0.3 0.7 3.0 0.4 376.2 0.0 1.2 0.5 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Group enriched" "Detected in many" 8 "dendritic cells: 53.2;T-cells: 162.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Cell line enriched" "Detected in some" 60 "RPMI-8226: 1113.4" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" 1.9 1.9 0.4 10.6 0.3 8.3 2.9 1.1 0.6 33.4 0.1 2.1 5.0 1.2 1.1 1.6 1.5 4.3 1.0 0.1 1.2 1.0 1.6 4.2 25.9 5.0 2.1 0.9 0.9 4.6 8.8 0.3 4.8 1.7 3.0 0.0 2.4 1.0 0.6 1.4 15.1 1.1 0.7 15.6 5.1 0.4 2.4 459.6 2.0 0.4 15.1 3.4 1.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.1 0.2 0.0 1113.4 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 42.0 1.0 0.8 15.7 1.1 79.3 0.7 1.9 601.8 0.6 1.2 4.6 1053.9 6.1 1.1 1.7 1.0 2.2 427.6 0.4 0.3 1.1 0.6 0.1 1.2 5.0 2.1 4.8 0.7 2.4 0.5 1.3 6.4 5.5 0.0 4.4 4.0 2.2 0.0 0.6 0.0 2.2 2.8 1.0 1.5 0.0 0.0 0.0 0.1 53.2 0.1 0.0 0.1 0.5 0.2 0.5 0.7 0.0 1.7 0.4 0.0 0.0 2.0 7.1 0.2 0.0 0.0 0.7 0.5 0.1 0.0 0.5 4.6 0.0 4.0 4.3 0.5 0.0 4.1 5.4 5.6 7.5 0.0 10.3 0.0 0.1 0.0 0.1 0.0 10.8 0.7 12.4 0.2 0.0 0.0 0.0 2.0 1.2 0.2 0.1 0.5 2.8 0.0 162.9 0.0 7.5 0.3 CD99L2 "CD99B, MIC2L1" ENSG00000102181 "CD99 molecule like 2" Q8TCZ2 X 150766336-150898816 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 179.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.1;Horizontal cells: 52.2;Inhibitory neurons: 57.2;Oligodendrocytes: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038782, HPA038783, HPA061400" Enhanced Supported "Plasma membrane" NA NA 1200000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA038782: AB_10795139, HPA038783: AB_10794734, HPA061400: AB_2732660" "unprognostic (2.10e-2)" "unprognostic (2.62e-3)" "unprognostic (3.12e-3)" "unprognostic (6.03e-3)" "unprognostic (1.22e-1)" "unprognostic (2.66e-1)" "unprognostic (5.56e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.74e-5)" "unprognostic (5.50e-2)" "unprognostic (5.13e-2)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (9.23e-2)" "prognostic unfavorable (8.74e-4)" 46.1 28.1 68.5 14.8 69.5 7.3 29.7 71.0 99.6 33.4 26.8 40.1 10.0 39.9 24.5 14.5 30.5 19.2 61.6 69.9 80.4 24.9 47.3 25.2 13.2 104.7 77.9 38.9 18.7 14.6 23.8 21.5 107.2 25.8 10.6 43.4 14.8 32.6 179.1 13.4 19.2 32.4 71.5 26.9 21.8 11.2 91.6 14.5 16.8 99.2 10.7 29.4 21.0 80.2 8.1 79.8 29.5 36.9 153.3 95.2 8.7 65.2 76.1 32.3 46.3 5.5 10.2 29.3 154.0 114.6 24.2 13.0 40.4 44.4 26.6 68.5 31.9 12.7 17.8 8.2 41.2 21.4 23.3 90.3 14.5 24.0 45.4 50.3 38.6 22.4 8.9 74.9 41.1 17.3 18.9 31.1 12.4 6.9 42.7 18.8 24.2 40.5 31.7 5.4 38.9 19.9 25.8 21.9 29.6 21.6 6.2 36.6 45.8 47.5 14.4 62.2 48.0 62.6 112.3 28.3 59.6 42.3 36.4 7.3 8.6 5.9 6.2 7.6 5.4 4.5 5.8 6.3 8.1 4.8 5.5 6.0 2.1 7.2 12.5 5.8 4.4 7.0 68.5 69.5 71.0 99.6 69.9 80.4 104.7 77.9 107.2 71.5 91.6 80.2 14.1 16.0 7.8 21.5 8.2 3.1 2.3 3.6 4.6 26.8 3.7 3.2 42.8 11.5 6.4 12.9 18.8 10.1 7.4 2.0 5.9 4.4 0.3 5.6 10.1 13.8 8.4 6.5 49.1 5.3 3.9 15.9 7.1 3.6 7.6 12.6 17.2 26.6 10.2 52.2 57.2 2.9 8.2 16.4 6.8 2.8 20.8 8.6 10.6 23.4 8.1 18.2 2.1 21.6 60.7 3.6 3.1 30.1 12.5 3.4 5.3 11.3 5.0 18.7 0.0 15.9 12.0 2.8 4.9 3.3 1.3 13.5 6.4 11.8 3.3 1.3 CDC14B "Cdc14B1, Cdc14B2, CDC14B3, hCDC14B" ENSG00000081377 "Cell division cycle 14B" O60729 9 96490241-96619843 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3" "Cell type enhanced" "Detected in many" "Astrocytes: 86.5;Excitatory neurons: 83.5;Inhibitory neurons: 110.2;Oligodendrocyte precursor cells: 156.9;Oligodendrocytes: 273.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 10.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064747 Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA064747: AB_2732719" "unprognostic (5.69e-2)" "unprognostic (9.09e-2)" "unprognostic (3.50e-2)" "unprognostic (8.08e-3)" "unprognostic (4.24e-1)" "unprognostic (1.19e-2)" "unprognostic (1.11e-2)" "unprognostic (4.49e-2)" "unprognostic (1.63e-2)" "unprognostic (2.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.75e-1)" "prognostic favorable (2.97e-10)" "unprognostic (2.01e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (7.40e-2)" 4.3 2.3 11.1 1.1 15.8 3.0 3.0 6.1 11.7 2.9 1.4 3.1 2.8 1.3 2.0 1.4 4.2 2.9 5.0 5.2 6.9 5.5 10.3 3.0 0.9 11.0 12.1 3.4 4.6 6.9 1.1 2.0 11.4 3.3 3.3 1.7 1.8 4.1 0.7 0.8 3.3 1.7 10.4 0.8 6.1 9.3 11.4 2.9 8.5 1.4 1.2 4.1 0.8 27.3 7.4 4.1 4.2 4.4 20.2 30.1 11.6 5.3 7.0 3.5 5.6 14.0 11.6 0.0 5.0 11.3 8.4 8.1 6.1 4.0 4.1 1.9 5.8 1.1 1.5 11.2 3.3 0.0 0.2 12.4 2.1 3.7 3.4 4.0 0.7 0.0 4.4 0.8 4.8 3.5 0.0 1.2 7.9 8.4 3.6 0.0 2.6 0.2 5.4 11.3 1.3 6.6 3.7 1.1 2.0 14.2 0.9 2.3 2.2 3.5 4.1 9.0 3.9 0.1 0.0 0.0 3.7 0.0 8.3 10.4 0.0 2.2 2.0 0.0 1.0 1.1 0.8 1.5 0.0 0.4 1.4 0.9 0.0 0.1 0.0 0.0 1.1 0.6 11.1 15.8 6.1 11.7 5.2 6.9 11.0 12.1 11.4 10.4 11.4 27.3 4.0 6.4 8.8 86.5 3.7 9.1 8.9 4.4 9.1 7.2 8.4 6.1 17.9 11.5 11.4 9.2 8.4 6.4 2.3 7.1 7.9 5.5 36.9 27.4 7.5 6.2 2.4 0.4 83.5 6.5 3.0 17.3 21.4 33.9 14.5 2.9 6.8 31.2 11.3 8.4 110.2 9.0 8.2 1.6 6.7 33.3 9.0 5.5 8.8 56.2 2.4 12.8 2.1 156.9 273.9 8.6 7.3 11.7 8.3 10.8 16.9 17.0 15.7 12.4 26.3 18.6 15.7 10.8 7.3 4.7 7.7 3.4 4.4 1.2 8.6 13.2 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188417 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;lymphoid tissue: 8.8;testis: 13.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 111.2;Early spermatids: 18.3;Late spermatids: 31.8;Spermatogonia: 16.3" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005855, HPA008803" Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Golgi apparatus" "HPA005855: AB_1846364, HPA008803: " "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.7 0.9 0.8 3.3 0.8 15.3 1.1 0.7 1.0 0.6 0.7 3.5 2.0 0.6 0.9 2.4 0.2 0.3 0.4 0.8 2.0 0.7 0.8 0.3 4.4 1.1 1.9 2.2 0.7 0.8 0.8 2.6 1.7 0.6 3.9 2.0 0.8 0.6 0.4 0.6 1.8 1.1 0.8 2.0 0.9 13.3 2.0 8.8 1.8 0.3 5.6 0.9 0.9 0.7 22.2 10.7 50.0 27.2 1.7 3.2 34.2 29.9 11.3 36.7 29.6 46.8 11.2 64.9 11.4 8.0 23.4 16.3 86.6 20.6 38.6 21.4 45.1 83.8 19.0 23.1 1.7 59.4 23.4 1.7 3.1 45.8 19.6 4.6 14.1 47.8 67.6 33.6 20.1 11.8 74.8 46.6 73.4 20.2 24.2 33.2 32.9 35.1 9.5 20.7 23.5 28.8 18.6 21.6 9.5 31.7 11.3 41.9 7.2 18.0 27.7 20.3 41.4 16.7 54.2 101.5 13.5 65.2 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.0 0.8 2.0 1.1 1.9 1.7 0.8 2.0 0.7 0.3 0.0 0.0 1.0 1.1 0.4 0.4 0.8 1.8 0.5 1.2 1.0 111.2 0.0 0.1 0.0 2.1 4.2 0.2 2.4 0.0 0.4 18.3 0.5 0.9 2.7 1.2 8.0 0.2 0.9 7.4 1.5 1.5 1.3 0.0 4.6 1.4 0.3 3.1 0.0 0.5 2.0 0.0 0.6 0.9 31.8 1.5 0.5 0.0 0.0 0.1 1.1 0.0 0.5 0.0 1.1 0.8 1.9 13.0 0.7 0.4 0.4 0.2 0.4 0.0 0.1 2.2 14.5 16.3 4.3 0.0 0.3 0.6 2.4 4.1 0.5 CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 320.3;Excitatory neurons: 447.6;Inhibitory neurons: 479.0;Oligodendrocyte precursor cells: 444.3;Oligodendrocytes: 671.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments" "CAB070414: AB_11156796, HPA071252: AB_2686374" "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" 15.6 12.5 26.3 5.5 32.4 3.5 12.2 33.5 30.0 15.8 12.2 21.2 14.7 15.0 7.7 10.1 12.6 13.7 16.4 24.9 25.2 17.3 14.7 12.3 2.0 25.7 26.8 14.0 13.1 19.7 14.6 12.7 27.0 15.8 10.3 23.7 7.6 14.9 11.4 6.3 12.9 14.5 19.8 6.6 22.4 24.4 29.7 2.2 8.1 13.6 1.8 23.0 11.3 37.0 22.6 21.1 21.9 10.4 21.5 26.4 7.7 25.4 35.7 17.2 17.9 17.1 50.1 0.1 26.6 42.4 13.0 10.3 16.3 14.2 20.9 0.1 13.2 17.4 25.5 6.7 24.3 14.1 7.5 18.6 17.9 27.8 27.8 21.3 58.0 13.6 45.1 0.1 28.2 6.2 0.4 2.5 18.0 29.3 20.0 0.0 37.0 0.1 27.7 43.1 15.7 22.9 43.0 17.8 24.8 13.4 23.1 0.8 59.0 31.3 16.2 36.1 33.9 0.1 0.1 0.1 41.4 0.0 42.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.3 32.4 33.5 30.0 24.9 25.2 25.7 26.8 27.0 19.8 29.7 37.0 82.6 41.7 35.7 320.3 0.8 11.7 26.0 15.9 12.0 97.7 14.0 12.8 59.9 30.0 38.9 44.1 118.9 5.9 1.8 49.3 13.7 26.0 128.0 18.7 45.1 68.4 26.4 45.6 447.6 41.1 7.3 44.4 92.8 25.7 7.0 21.5 47.8 28.9 3.7 223.8 479.0 30.5 22.4 4.4 9.9 132.3 44.1 6.4 16.0 180.8 5.9 33.4 0.0 444.3 671.8 65.1 74.0 85.4 1.8 30.1 50.7 41.3 24.8 66.9 78.9 64.0 68.4 45.6 57.7 8.0 8.0 1.4 1.3 23.4 34.4 43.1 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 CDC45 "CDC45L, CDC45L2" ENSG00000093009 "Cell division cycle 45" O75419 22 19479457-19520612 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;lymphoid tissue: 20.4;testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Erythroid cells: 29.7;Spermatocytes: 72.3;Spermatogonia: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "K-562: 370.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000614, CAB009459" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "CAB009459: AB_2078507, HPA000614: AB_1078487" "unprognostic (5.56e-2)" "unprognostic (6.12e-3)" "unprognostic (1.17e-3)" "unprognostic (3.42e-3)" "unprognostic (3.57e-1)" "unprognostic (7.42e-2)" "prognostic unfavorable (6.95e-6)" "unprognostic (6.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (8.94e-4)" "unprognostic (7.28e-2)" "unprognostic (0.00e+0)" "unprognostic (7.62e-3)" "unprognostic (2.02e-1)" "unprognostic (8.52e-2)" "unprognostic (1.10e-1)" 0.5 0.5 0.7 6.2 0.5 25.4 1.5 0.2 0.2 1.1 0.4 4.6 3.5 0.9 0.3 5.3 0.4 0.5 0.3 0.2 0.4 0.3 1.2 0.9 11.3 0.5 0.4 0.2 0.2 0.2 0.1 3.2 0.5 0.4 6.0 0.1 0.9 0.2 0.1 3.3 3.1 1.8 0.2 2.8 2.6 23.4 1.1 20.4 0.3 0.0 11.8 1.9 1.7 0.3 57.4 42.2 56.4 42.9 2.0 5.6 24.4 65.4 31.6 75.5 75.5 35.8 30.5 62.2 23.2 21.0 28.9 51.9 58.2 45.9 59.5 72.3 96.3 82.8 50.1 41.3 3.1 125.0 43.7 1.3 2.4 57.9 26.0 7.0 38.8 63.0 370.6 73.3 44.8 77.2 98.1 56.5 16.7 106.2 34.4 77.1 95.5 26.5 16.9 49.3 72.1 37.0 38.1 40.0 12.0 21.7 26.2 51.0 15.0 60.0 91.6 46.0 62.8 24.6 46.8 67.5 30.1 58.9 82.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.2 0.1 0.5 0.5 0.1 0.3 0.9 0.6 0.7 0.5 0.2 0.2 0.2 0.4 0.5 0.4 0.5 0.2 1.1 0.3 0.2 0.0 0.0 0.0 1.9 2.7 1.7 3.7 0.0 0.0 0.7 0.8 0.4 0.0 0.5 0.0 0.0 11.9 1.4 1.9 0.0 0.8 120.5 0.9 0.7 1.2 0.0 29.7 0.1 0.0 19.8 2.3 1.5 1.0 0.0 5.5 3.6 0.0 7.2 0.0 0.1 1.2 4.1 0.6 1.0 14.4 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.7 12.6 0.2 0.4 0.0 0.3 0.0 6.6 1.5 13.9 72.3 50.7 3.3 1.8 4.9 1.2 0.8 5.1 2.5 CDCA4 "FLJ20764, Hepp" ENSG00000170779 "Cell division cycle associated 4" Q9BXL8 14 105009573-105021083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 55.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 64.2;Cytotrophoblasts: 84.5;Extravillous trophoblasts: 154.5;Spermatogonia: 69.9;Suprabasal keratinocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA064971 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA064971: AB_2685395" "unprognostic (2.22e-3)" "unprognostic (1.84e-1)" "unprognostic (2.69e-1)" "unprognostic (9.93e-3)" "unprognostic (1.42e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (4.19e-4)" "prognostic unfavorable (7.94e-4)" "unprognostic (4.20e-2)" "unprognostic (8.54e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (2.15e-1)" "unprognostic (1.55e-1)" "unprognostic (7.50e-2)" "unprognostic (1.24e-2)" 3.9 2.6 1.9 7.4 2.0 55.8 4.2 3.0 2.1 8.7 2.1 4.6 4.7 5.4 1.8 18.6 4.1 2.6 2.7 1.7 1.8 3.4 2.7 3.6 11.6 2.1 1.9 4.1 3.2 1.8 1.7 9.2 2.1 3.8 2.9 1.3 5.5 2.2 1.4 24.7 4.9 3.5 1.9 6.6 3.8 11.6 2.0 14.6 3.3 1.5 8.5 4.2 10.2 2.0 40.6 41.3 46.7 35.6 7.9 13.2 61.1 59.0 18.0 45.2 39.7 50.9 50.2 52.9 31.5 20.9 34.5 63.5 32.9 68.0 27.1 58.2 26.1 33.4 33.9 43.2 9.7 59.8 27.0 9.4 20.8 35.2 32.7 15.1 31.4 45.0 37.5 53.0 32.1 98.8 56.2 40.1 34.8 35.1 94.0 53.6 68.1 19.7 15.9 46.2 27.2 33.5 56.6 22.3 46.8 20.5 44.0 39.8 48.8 39.9 50.5 55.3 79.5 19.5 25.9 54.4 33.5 30.2 67.5 1.1 4.3 10.6 11.9 4.9 14.8 8.4 12.7 16.7 4.7 5.4 7.4 8.9 1.6 12.9 5.6 5.1 11.1 7.0 1.9 2.0 3.0 2.1 1.7 1.8 2.1 1.9 2.1 1.9 2.0 2.0 5.4 0.0 2.2 0.7 7.4 64.2 26.5 36.6 13.1 3.4 8.7 8.3 0.6 0.0 9.0 1.8 0.0 84.5 11.5 4.3 3.9 12.7 8.1 9.0 9.0 10.9 3.0 53.0 1.8 7.0 154.5 10.2 3.1 12.5 28.6 15.1 7.9 2.2 24.3 13.5 1.3 6.6 6.1 5.9 22.6 6.8 8.4 8.4 17.8 2.8 9.3 4.6 9.2 1.0 1.8 12.3 3.3 6.0 11.8 16.1 1.9 1.8 7.7 2.6 6.6 4.6 12.5 43.0 69.9 21.3 67.1 25.9 17.7 3.6 9.5 43.2 CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 15.2;ovary: 6.1" "Group enriched" "Detected in some" 13 "Early spermatids: 27.1;granulocytes: 79.1;Late spermatids: 40.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "Group enriched" "Detected in some" 28 "basophil: 1.8;eosinophil: 3.7" "Lineage enriched" "Detected in single" 37 "granulocytes: 3.7" "Cell line enhanced" "Detected in some" "BJ hTERT+: 22.6;BJ hTERT+ SV40 Large T+ RasG12V: 20.7;HBF TERT88: 30.9;HMC-1: 58.4;LHCN-M2: 19.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "Golgi apparatus" "HPA015786: AB_1844780" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.80e-2)" "unprognostic (7.38e-2)" "unprognostic (9.99e-5)" "unprognostic (6.31e-2)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" 0.7 0.3 0.0 0.2 0.0 0.0 0.8 2.4 0.4 0.8 0.0 0.5 0.3 0.6 15.2 0.6 0.5 1.9 0.2 0.5 0.0 0.3 0.0 1.0 0.1 0.4 0.1 6.1 0.1 0.2 0.3 0.0 0.4 0.7 0.7 0.0 0.3 0.3 0.9 0.6 0.8 0.4 0.1 0.0 0.7 1.9 0.1 0.2 0.1 0.7 0.1 0.8 0.5 0.3 0.3 0.0 0.0 0.0 1.6 2.8 0.0 5.9 22.6 10.2 20.7 0.0 3.0 0.0 0.0 2.3 0.5 0.0 0.0 0.0 30.9 0.0 0.1 1.9 0.0 0.0 0.3 0.1 58.4 3.4 0.0 2.7 1.5 0.4 0.0 0.0 0.0 0.1 19.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.5 2.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.4 0.5 0.0 0.4 0.1 0.4 0.1 0.1 0.3 0.1 0.0 1.3 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.8 0.0 0.0 79.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 40.3 0.3 0.1 3.6 1.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.5 0.2 0.0 0.1 0.0 0.9 0.1 0.0 0.0 CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967752-21995301 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7;pituitary gland: 33.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 170.1;Club cells: 145.9;Early spermatids: 227.5;Late spermatids: 447.9;Pancreatic endocrine cells: 417.7;Respiratory ciliated cells: 221.9" "Cancer enhanced" "Detected in all" "cervical cancer: 49.9;ovarian cancer: 57.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 37.4" "Group enriched" "Detected in many" 6 "B-cells: 15.6;T-cells: 37.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 289.2;HEK 293: 389.7;HeLa: 311.1;SK-MEL-30: 318.7" "Low region specificity" "Detected in some" "CAB000093, CAB000445, CAB018232, HPA047838" Enhanced Supported Nucleoli NA NA 18000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoli "CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174" "unprognostic (3.41e-2)" "unprognostic (4.51e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (1.82e-7)" "unprognostic (5.22e-2)" "prognostic favorable (5.19e-4)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.41e-2)" "unprognostic (1.22e-2)" "unprognostic (3.05e-2)" "unprognostic (3.55e-1)" 3.7 10.1 7.4 1.7 8.3 1.3 3.1 5.9 8.5 1.1 31.7 1.9 0.8 0.7 1.0 7.4 2.2 0.5 0.7 6.7 6.4 0.5 0.7 2.3 2.1 7.4 5.8 0.8 1.5 2.1 33.7 2.6 7.2 2.1 0.7 0.1 1.6 1.6 0.6 0.9 3.6 0.3 6.2 5.5 3.9 14.8 8.0 2.1 1.3 0.0 2.5 2.4 2.3 9.2 11.8 0.0 1.7 82.2 0.8 0.9 39.1 15.9 0.0 111.7 196.0 19.1 289.2 47.1 167.7 9.5 0.0 36.0 34.3 211.0 91.4 212.2 389.7 0.1 311.1 13.6 8.8 22.4 17.3 21.2 0.0 112.2 61.9 236.3 11.7 0.0 0.1 188.4 105.7 0.8 1.9 0.0 2.6 24.2 185.9 0.2 80.2 166.3 23.4 0.0 195.2 14.0 219.9 36.6 318.7 9.4 42.8 0.7 39.5 0.9 2.6 0.3 0.5 84.7 49.6 177.8 0.2 62.9 1.0 1.5 2.1 0.3 9.9 1.3 14.1 11.1 11.4 17.6 0.3 15.6 0.6 6.7 0.5 0.8 4.2 0.0 37.4 3.6 7.4 8.3 5.9 8.5 6.7 6.4 7.4 5.8 7.2 6.2 8.0 9.2 1.6 0.0 0.0 1.0 11.5 1.8 2.3 170.1 0.0 0.6 6.1 10.4 4.2 0.0 145.9 11.0 0.0 27.9 6.2 8.1 0.0 29.7 227.5 36.4 6.7 2.6 70.9 0.0 1.2 26.4 43.8 7.7 0.0 6.2 4.5 4.6 1.4 0.3 7.6 0.0 3.5 6.3 122.1 10.5 4.2 447.9 3.1 2.9 8.8 7.5 16.2 0.9 5.2 4.5 6.6 417.7 12.1 1.9 38.7 35.4 32.8 0.0 221.9 0.1 0.0 1.1 20.8 7.2 6.2 7.2 0.4 9.2 12.7 11.0 3.8 54.4 CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.2;intestine: 30.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 240.7;Pancreatic endocrine cells: 164.5;Proximal enterocytes: 139.0;Squamous epithelial cells: 142.0;Urothelial cells: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.1;HaCaT: 35.0;HeLa: 33.9;hTERT-RPE1: 60.1;SiHa: 48.0;SK-MEL-30: 35.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000349, HPA052838, HPA063327" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB000349: , HPA052838: , HPA063327: AB_2684987" "unprognostic (2.30e-1)" "unprognostic (9.23e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.47e-6)" "unprognostic (2.10e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.01e-1)" "unprognostic (3.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (9.14e-3)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.28e-2)" 18.7 1.9 2.0 2.9 1.8 0.4 8.6 1.1 1.9 9.6 9.1 22.4 21.7 3.8 0.6 36.2 1.7 2.4 1.0 1.6 2.2 1.2 1.2 12.6 1.1 2.7 1.5 0.9 1.2 3.3 3.5 2.3 2.3 3.6 19.7 2.8 6.7 4.7 7.2 12.9 30.9 2.1 1.7 4.6 6.0 5.3 2.4 0.8 1.1 1.1 8.1 7.9 20.2 2.4 0.0 0.0 0.3 2.1 28.2 38.1 0.7 1.8 0.0 4.6 12.6 3.6 10.3 0.0 3.4 2.3 0.0 35.0 0.8 6.9 5.5 2.6 9.7 0.0 33.9 1.5 14.4 1.1 6.1 8.1 0.0 6.5 25.8 60.1 4.4 0.0 0.0 17.1 7.3 2.8 0.0 0.1 1.7 1.7 19.5 0.0 2.4 0.7 10.0 0.0 5.4 0.1 48.0 11.5 35.7 25.8 3.0 0.0 14.8 0.0 0.7 0.1 0.0 13.5 8.4 0.1 0.0 1.0 0.0 0.0 3.3 0.0 0.1 3.3 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.1 0.0 0.0 9.0 0.0 0.0 1.0 2.0 1.8 1.1 1.9 1.6 2.2 2.7 1.5 2.3 1.7 2.4 2.4 3.5 67.3 6.7 0.3 2.9 5.4 27.0 40.5 5.7 3.2 6.4 9.8 3.1 1.5 37.5 5.5 0.0 1.2 3.2 240.7 0.0 57.7 11.3 31.8 7.5 4.1 7.7 0.0 0.1 38.2 0.8 11.5 30.5 37.2 0.0 0.4 1.8 0.1 1.2 0.0 0.5 31.6 14.2 17.6 3.8 2.7 0.6 5.6 3.6 2.8 3.2 4.8 0.0 1.0 0.5 164.5 75.6 1.2 2.1 65.3 139.0 0.1 17.9 7.2 0.0 2.7 8.9 13.8 3.5 142.0 24.2 3.1 2.9 1.2 23.3 241.6 CDON "CDO, CDON1, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 58.3;Fibroblasts: 23.5;Inhibitory neurons: 49.5;Muller glia cells: 39.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 23.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;ASC diff: 32.7;RH-30: 48.9;SuSa: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB012422, HPA017377" Uncertain NA NA 15000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB012422: AB_2260246, HPA017377: AB_1846453" "prognostic favorable (1.35e-4)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-4)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (5.83e-3)" "unprognostic (1.86e-4)" 12.6 0.7 1.9 1.6 2.0 0.0 5.1 23.0 4.0 7.9 1.2 12.4 1.0 14.0 2.1 1.7 14.2 4.8 4.0 1.6 1.8 0.8 1.2 2.7 1.1 2.2 1.9 20.6 1.2 2.5 3.0 2.7 2.7 1.3 1.6 10.1 1.7 2.8 1.2 9.9 2.9 17.0 0.5 0.7 4.6 3.6 2.3 2.8 18.5 1.6 1.5 2.5 3.0 2.1 1.6 3.2 28.4 2.8 32.7 14.5 0.4 0.5 2.9 0.9 0.3 1.1 9.4 1.4 6.8 0.6 3.3 0.4 7.1 1.0 0.8 5.5 6.3 0.5 6.5 2.9 6.4 0.4 1.8 4.5 1.2 0.6 0.0 12.2 0.3 4.8 0.1 1.9 2.7 0.4 3.6 1.0 2.6 0.8 3.7 1.1 48.9 0.9 1.7 0.5 2.4 9.6 3.7 0.3 4.7 23.8 2.4 1.0 0.5 3.2 2.2 6.3 3.3 2.5 5.5 0.2 2.0 1.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 23.0 4.0 1.6 1.8 2.2 1.9 2.7 0.5 2.3 2.1 3.0 6.4 9.9 11.1 0.1 15.2 1.4 0.8 2.2 5.1 5.4 1.9 5.2 2.8 5.6 0.0 16.7 0.6 0.1 0.2 0.0 1.3 3.1 1.7 0.5 3.0 7.7 0.4 58.3 0.6 0.4 23.5 1.5 1.1 0.0 1.8 1.1 2.1 0.3 0.0 49.5 0.3 0.0 0.0 7.6 2.7 14.9 0.2 3.6 2.8 0.1 39.3 0.0 14.1 5.8 2.4 0.4 11.3 0.8 1.1 0.6 0.5 4.2 4.6 0.0 2.9 2.7 1.8 3.8 0.5 10.7 0.7 0.6 13.2 0.4 1.6 CDT1 "DUP, RIS2" ENSG00000167513 "Chromatin licensing and DNA replication factor 1" Q9H211 16 88803789-88809258 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 38.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.4;Erythroid cells: 71.3;Extravillous trophoblasts: 92.0;Spermatogonia: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 149.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017224 Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA017224: AB_1846468" "unprognostic (1.33e-1)" "unprognostic (2.04e-2)" "unprognostic (7.32e-2)" "unprognostic (2.67e-1)" "unprognostic (4.34e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (3.44e-3)" "unprognostic (2.81e-2)" "unprognostic (4.59e-2)" "unprognostic (1.21e-1)" "unprognostic (9.34e-2)" "prognostic unfavorable (2.69e-6)" "unprognostic (7.72e-3)" "unprognostic (5.79e-2)" "unprognostic (2.80e-2)" "unprognostic (8.54e-2)" 0.7 0.8 0.8 3.8 1.2 38.5 0.7 2.5 1.3 1.7 0.0 3.3 4.1 0.5 0.2 6.7 0.5 0.2 0.5 0.8 2.3 0.7 1.0 1.3 4.8 2.2 1.1 0.4 0.6 1.3 2.1 2.8 1.9 0.7 1.6 0.4 1.1 0.2 0.1 3.6 3.9 0.6 0.7 3.1 2.4 3.5 1.1 8.7 0.6 0.0 3.3 0.5 2.3 1.0 33.6 34.5 16.5 25.3 0.7 3.4 64.2 24.1 6.6 19.4 12.0 79.3 33.8 51.4 24.2 5.5 12.7 46.0 21.6 17.7 6.2 18.2 92.1 51.8 28.8 59.9 0.3 28.8 21.5 1.8 1.4 19.8 4.4 1.6 5.9 60.9 80.8 18.4 7.6 90.6 109.3 149.4 41.8 12.2 31.6 120.3 22.9 42.4 4.3 23.8 36.6 26.2 44.4 13.1 16.9 7.4 39.0 55.9 5.9 24.6 42.6 37.2 35.4 61.4 55.7 73.6 19.3 71.9 31.6 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.7 0.4 0.1 0.1 0.7 0.2 0.8 1.2 2.5 1.3 0.8 2.3 2.2 1.1 1.9 0.7 1.1 1.0 0.4 0.0 1.1 0.7 4.9 11.2 4.3 1.4 7.4 0.7 5.4 7.5 2.2 1.5 1.7 1.8 0.0 51.4 2.2 12.7 1.9 1.1 0.4 1.4 1.4 2.2 2.4 71.3 0.2 0.0 92.0 5.2 9.2 2.2 0.0 29.0 0.4 1.0 19.5 0.0 0.8 16.1 4.1 5.6 5.5 1.2 0.3 2.8 1.8 0.0 1.9 1.5 4.1 0.0 0.6 0.6 2.3 0.4 23.1 2.2 2.0 1.6 2.1 1.9 0.0 2.1 3.4 6.6 37.1 10.8 7.1 24.8 5.4 5.7 30.1 4.4 CDYL "CDYL1, DKFZP586C1622" ENSG00000153046 "Chromodomain Y like" Q9Y232 6 4706159-4955551 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Lyase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035578 Enhanced Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 52: Non-specific - Ribosome" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "HPA035578: AB_2674685" "unprognostic (1.25e-1)" "unprognostic (8.99e-2)" "unprognostic (6.03e-2)" "unprognostic (2.38e-3)" "prognostic favorable (1.53e-4)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.62e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.09e-1)" "unprognostic (5.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (2.60e-2)" "unprognostic (3.94e-1)" 14.0 6.0 6.9 10.2 6.8 20.0 11.5 5.0 6.7 15.0 4.9 13.0 7.0 15.2 10.5 16.8 10.6 8.4 10.4 6.0 6.4 7.2 5.6 8.9 12.1 6.6 6.2 9.9 7.5 12.4 5.1 18.2 6.0 7.6 13.2 6.7 9.0 11.9 19.5 17.8 9.0 14.5 5.6 9.6 9.2 9.0 6.7 9.3 9.7 12.7 12.9 15.6 13.0 6.9 23.7 22.1 30.1 25.5 23.3 15.9 34.4 23.1 17.9 21.3 22.9 18.0 17.2 5.3 22.1 17.6 33.3 19.8 24.2 28.2 24.9 16.4 20.2 20.9 21.0 16.4 28.5 27.9 21.7 12.5 49.8 25.0 37.5 12.9 20.6 19.2 37.9 16.2 10.8 22.9 14.8 25.9 32.6 17.9 21.3 19.0 26.2 43.7 14.7 20.5 25.5 15.4 28.5 24.9 36.9 86.5 15.0 26.3 28.1 25.2 21.6 18.5 26.8 33.7 57.8 18.4 8.3 17.7 28.1 5.3 1.3 0.6 1.5 0.6 1.1 1.0 1.1 1.2 1.6 1.1 0.7 1.1 0.4 1.6 0.8 6.8 0.1 1.3 6.9 6.8 5.0 6.7 6.0 6.4 6.6 6.2 6.0 5.6 6.7 6.9 32.7 19.2 9.4 28.7 18.4 37.3 23.9 11.9 10.8 16.7 31.2 35.8 18.8 14.3 12.0 14.7 22.9 12.9 64.5 44.7 15.6 10.8 62.8 26.9 43.2 22.9 32.3 41.5 52.3 10.4 22.0 18.7 6.1 60.3 5.7 24.3 18.9 11.7 10.5 45.4 41.5 26.6 6.1 17.3 57.9 74.9 5.9 28.1 8.8 101.2 22.7 25.4 19.6 54.3 64.1 16.8 41.8 8.2 22.3 30.1 4.6 10.7 12.1 25.7 6.6 29.7 20.9 10.4 25.3 9.8 41.9 63.8 17.5 10.9 22.6 56.9 CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.9;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.2;RPTEC TERT1: 15.8;TIME: 20.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: AB_2669006, HPA052865: AB_2681976" "unprognostic (2.91e-1)" "unprognostic (5.29e-3)" "unprognostic (6.96e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-2)" "unprognostic (8.43e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-9)" "unprognostic (8.01e-3)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.70e-1)" 3.9 5.6 3.7 1.3 3.7 1.5 3.8 4.9 5.1 7.0 3.5 4.7 3.0 5.2 1.7 5.1 6.8 2.4 11.7 4.0 3.8 9.4 8.2 8.2 1.1 2.8 3.0 6.6 8.9 1.5 7.0 2.2 2.7 7.8 3.4 2.4 5.7 3.1 13.8 12.4 3.8 3.1 1.9 3.5 4.6 5.7 3.7 0.9 6.5 3.4 2.2 4.2 8.7 4.7 5.1 10.3 1.5 1.0 3.5 4.0 3.8 2.8 4.2 0.9 1.8 0.4 1.1 0.1 1.0 3.8 1.0 6.2 2.6 1.1 0.8 1.5 5.8 0.1 6.7 1.7 3.6 0.2 1.0 1.3 10.0 2.6 6.1 12.2 2.4 0.7 0.3 0.3 1.4 1.2 0.0 0.6 0.9 1.4 1.1 0.0 1.8 0.2 15.8 1.2 1.9 0.5 1.1 1.1 0.9 1.4 1.4 0.3 20.9 0.4 6.8 1.5 0.9 0.1 0.3 0.0 0.5 2.0 1.7 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.7 3.7 4.9 5.1 4.0 3.8 2.8 3.0 2.7 1.9 3.7 4.7 3.6 3.2 2.2 2.0 0.0 2.0 0.9 2.1 1.2 2.9 1.9 1.5 4.5 1.5 2.4 0.0 0.0 0.2 0.1 2.1 0.0 1.6 3.8 0.9 0.9 4.1 1.8 0.0 7.9 3.3 0.2 1.0 3.6 2.4 0.0 0.8 4.6 2.6 0.3 0.0 6.1 2.3 4.1 0.6 0.8 1.9 3.1 0.5 0.0 1.9 0.4 0.3 1.0 2.0 2.4 4.5 2.6 2.6 0.0 1.8 1.2 0.4 1.8 0.6 0.0 8.8 1.7 3.1 0.9 1.2 6.0 0.0 0.2 1.6 2.5 0.9 CEACAM6 "CD66c, NCA" ENSG00000086548 "CEA cell adhesion molecule 6" P40199 19 41750977-41772211 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 181.5;esophagus: 195.2;intestine: 220.3;lung: 286.7;salivary gland: 177.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 942.3;Club cells: 322.1;Distal enterocytes: 640.1;Paneth cells: 391.1;Urothelial cells: 182.3" "Group enriched" "Detected in many" 4 "cervical cancer: 139.4;colorectal cancer: 500.8;lung cancer: 344.1;pancreatic cancer: 437.5;stomach cancer: 231.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 11 "OE19: 1799.0" "CAB008370, HPA011041" Enhanced NA NA 86000000 "Cluster 24: B-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB008370: AB_592067, HPA011041: AB_1078481" "unprognostic (1.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.62e-2)" "unprognostic (8.22e-2)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (2.32e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "unprognostic (5.22e-2)" "unprognostic (3.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.42e-4)" "unprognostic (4.08e-1)" "unprognostic (8.71e-3)" "unprognostic (2.85e-1)" "unprognostic (7.68e-2)" 2.0 0.4 0.3 29.7 1.2 181.5 2.7 0.6 0.6 39.2 0.0 195.0 33.0 0.6 1.8 195.2 8.2 130.1 0.2 0.2 0.0 0.3 0.7 286.7 0.3 0.3 0.1 0.4 5.2 0.1 0.3 0.5 0.2 2.4 220.3 0.0 177.6 1.4 0.1 6.8 24.4 6.6 0.0 2.4 15.5 0.4 0.3 2.1 0.3 0.0 32.5 9.6 79.1 0.4 0.1 162.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 5.5 4.6 0.0 0.2 0.0 0.5 19.4 0.0 0.0 0.1 0.3 0.2 0.0 0.5 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.1 11.2 0.1 0.2 0.2 1799.0 4.5 0.1 0.0 0.1 1.0 0.7 1.8 0.1 0.0 4.2 0.0 0.2 0.6 1.9 0.4 0.2 0.3 0.5 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.5 0.1 0.0 3.1 0.3 1.2 0.6 0.6 0.2 0.0 0.3 0.1 0.2 0.0 0.3 0.4 0.0 942.3 84.5 0.0 2.3 0.0 4.9 17.9 0.0 0.0 3.5 2.0 0.2 75.8 322.1 0.0 0.0 0.0 0.0 640.1 0.0 77.0 0.2 0.4 0.1 1.3 5.4 0.0 0.1 16.3 0.0 1.3 1.5 0.8 7.0 0.0 0.4 0.3 0.0 0.0 0.1 102.3 14.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.7 391.1 0.0 0.0 24.2 5.7 0.0 71.8 0.0 0.0 0.0 9.9 0.0 0.1 15.6 0.0 0.0 1.2 0.0 31.7 182.3 CECR2 KIAA1740 ENSG00000099954 "CECR2 histone acetyl-lysine reader" Q9BXF3 22 17359949-17558149 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;retina: 15.6;skeletal muscle: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 109.4;Cone photoreceptor cells: 168.9;Oligodendrocyte precursor cells: 120.1;Oligodendrocytes: 137.7;Rod photoreceptor cells: 94.1" "Cancer enriched" "Detected in many" 6 "testis cancer: 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 15.5;HAP1: 14.4;K-562: 8.3;NTERA-2: 22.8;SCLC-21H: 10.1;SuSa: 9.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002943 Approved Approved Nucleoplasm,Vesicles No No "Cluster 54: Non-specific - Microtubule organization" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA002943: AB_1078496" "unprognostic (2.46e-2)" "unprognostic (4.10e-2)" "unprognostic (7.99e-2)" "unprognostic (1.92e-3)" "unprognostic (7.48e-3)" "unprognostic (2.46e-3)" "unprognostic (2.49e-1)" "unprognostic (6.67e-2)" "unprognostic (8.18e-2)" "unprognostic (3.94e-1)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (8.13e-6)" "unprognostic (1.13e-1)" "unprognostic (1.59e-1)" "unprognostic (6.56e-2)" "unprognostic (1.94e-2)" 0.7 0.4 5.2 0.2 12.8 0.5 1.0 22.5 8.3 1.4 1.2 1.2 0.2 2.3 0.6 0.4 1.7 0.2 3.4 5.3 8.0 1.3 7.6 2.6 0.1 9.8 9.0 2.9 2.6 0.0 6.4 1.0 8.7 1.0 0.3 15.6 0.9 0.2 21.8 0.9 0.5 0.9 5.4 0.4 0.5 3.5 9.8 0.2 2.2 10.6 0.2 1.3 1.0 12.7 0.2 0.1 15.5 5.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 0.7 0.1 14.4 0.0 0.0 0.0 7.2 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.5 8.3 0.0 0.0 0.1 0.0 0.5 22.8 0.0 0.0 1.8 1.0 0.1 0.0 5.1 10.1 0.0 0.0 0.2 0.9 9.0 1.6 2.5 0.1 0.1 3.4 0.0 0.0 5.8 1.4 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 12.8 22.5 8.3 5.3 8.0 9.8 9.0 8.7 5.4 9.8 12.7 1.9 6.4 10.6 109.4 0.3 0.0 1.1 0.2 0.0 22.1 0.7 0.6 11.8 0.0 0.8 1.8 168.9 10.1 0.0 0.0 0.0 0.1 6.3 6.3 6.2 2.0 0.0 0.0 2.3 0.2 2.5 3.1 0.0 17.2 0.0 3.5 4.2 10.7 0.7 5.0 4.3 0.0 0.0 0.3 0.3 4.0 1.2 1.4 0.0 34.7 0.2 18.3 0.0 120.1 137.7 0.1 0.0 1.2 0.8 1.8 0.0 1.4 0.9 94.1 6.6 33.9 3.2 1.9 15.9 0.1 0.1 33.0 0.2 0.4 0.0 3.6 CENPH ENSG00000153044 "Centromere protein H" Q9H3R5 5 69189574-69210357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33.8;testis: 29.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 74.5;Spermatocytes: 222.7;Spermatogonia: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA036494 Approved Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "HPA036494: AB_10673354" "unprognostic (1.49e-1)" "prognostic favorable (6.86e-4)" "unprognostic (1.73e-2)" "unprognostic (3.16e-2)" "unprognostic (2.32e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.22e-5)" "unprognostic (6.14e-3)" "unprognostic (6.85e-2)" "prognostic favorable (2.50e-4)" "unprognostic (4.21e-2)" "unprognostic (8.80e-2)" "prognostic unfavorable (5.11e-15)" "unprognostic (1.17e-1)" "unprognostic (3.94e-1)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" 4.2 2.0 1.4 7.5 1.7 33.8 7.7 1.7 2.0 3.9 1.0 7.4 6.5 4.5 2.1 7.5 4.0 1.8 4.0 1.5 1.6 1.6 3.6 2.8 17.7 1.6 1.5 3.9 1.5 2.0 1.4 5.2 1.6 3.3 8.1 2.5 2.9 2.3 4.0 9.2 5.9 3.7 1.4 5.2 3.7 29.7 1.6 18.5 2.5 4.0 18.8 3.8 4.4 2.2 64.6 19.4 88.6 70.2 5.8 18.3 48.0 31.2 32.6 66.9 71.8 26.5 79.6 138.9 36.6 18.1 39.1 47.0 59.0 70.4 85.1 42.7 41.4 32.7 32.5 26.4 2.0 47.1 32.1 7.1 14.6 43.6 47.7 18.9 23.2 73.7 58.7 53.3 52.2 35.6 152.4 67.3 78.1 20.7 17.0 93.2 118.2 108.2 21.1 22.9 61.6 81.9 34.6 22.8 27.5 47.7 31.9 31.4 11.4 33.4 56.1 44.5 78.7 65.5 106.3 111.8 51.1 94.2 64.7 1.0 2.0 3.0 4.7 3.5 7.7 13.3 7.9 6.0 3.1 14.1 9.9 8.6 0.4 8.6 4.2 6.7 9.7 4.8 1.4 1.7 1.7 2.0 1.5 1.6 1.6 1.5 1.6 1.4 1.6 2.2 4.8 0.0 2.6 1.0 18.3 36.7 17.7 17.4 9.6 3.4 10.8 11.7 3.3 4.3 7.1 0.0 0.0 37.4 9.2 5.1 0.0 12.3 26.5 5.5 5.1 6.9 1.2 74.5 1.3 9.1 49.0 7.4 2.6 4.8 5.1 22.4 4.6 1.1 17.0 0.0 1.1 9.5 12.2 7.5 18.2 22.5 3.7 6.3 8.8 1.0 4.3 7.3 6.2 1.0 0.9 7.0 2.5 4.9 14.4 6.9 1.4 3.4 10.8 3.5 19.7 6.4 9.3 222.7 222.8 12.1 19.2 10.0 12.0 6.9 15.9 15.2 CENPK "CENP-K, FKSG14, SOLT" ENSG00000123219 "Centromere protein K" Q9BS16 5 65517766-65563168 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.6;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.9;Extravillous trophoblasts: 50.6;Spermatocytes: 101.3;Spermatogonia: 75.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (4.04e-2)" "unprognostic (1.77e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-2)" "unprognostic (1.85e-1)" "unprognostic (3.04e-3)" "unprognostic (3.69e-4)" "unprognostic (3.22e-3)" "unprognostic (9.59e-3)" "unprognostic (3.32e-2)" "unprognostic (3.16e-3)" "unprognostic (1.98e-2)" "unprognostic (6.33e-15)" "unprognostic (2.22e-1)" "unprognostic (2.97e-1)" "unprognostic (8.42e-2)" "unprognostic (3.11e-1)" 1.1 0.9 0.6 10.6 0.7 24.6 3.8 1.0 0.8 1.2 1.6 9.0 8.3 1.9 0.9 5.6 2.3 1.9 0.5 0.5 0.6 0.8 1.9 2.0 14.6 1.0 0.7 0.8 0.6 1.0 0.3 5.5 1.1 1.3 11.9 0.7 1.4 0.7 0.2 8.6 8.6 3.4 0.7 4.5 5.5 13.4 1.0 22.2 1.2 0.5 12.4 2.6 2.4 1.4 65.3 41.4 85.6 29.5 4.4 12.0 40.8 69.8 26.5 58.7 73.6 35.1 97.2 39.3 25.2 23.6 59.5 39.7 33.3 35.4 92.7 45.2 28.5 42.1 50.7 33.8 1.7 50.1 36.8 5.6 5.0 56.9 27.3 10.6 56.4 42.2 31.8 57.7 59.1 21.5 85.4 56.2 41.1 18.5 17.1 52.5 81.9 43.8 38.8 34.4 35.8 28.9 53.7 22.1 28.7 31.8 40.0 36.9 20.3 44.9 46.5 31.1 82.2 30.0 51.9 83.0 41.9 74.0 49.9 3.7 0.7 2.3 9.9 1.0 14.8 4.0 21.1 12.5 1.7 7.0 28.5 20.2 1.7 10.2 1.1 1.6 23.2 10.0 0.6 0.7 1.0 0.8 0.5 0.6 1.0 0.7 1.1 0.7 1.0 1.4 2.7 0.0 3.4 0.3 11.7 23.6 8.5 14.0 4.6 1.6 6.0 7.9 0.9 0.0 8.1 0.0 0.0 28.8 18.7 5.8 1.9 3.1 27.6 25.5 4.5 5.7 0.0 50.9 3.1 1.0 50.6 6.3 9.2 7.2 2.5 22.7 3.9 1.1 22.4 0.0 2.3 14.7 8.2 1.9 12.0 17.4 1.5 5.7 1.8 11.2 1.8 0.6 7.2 2.0 1.4 2.3 2.1 1.5 14.1 2.2 1.1 0.3 7.1 1.1 0.0 2.3 9.1 101.3 75.1 17.0 8.1 6.7 20.7 3.9 15.8 11.4 CENPN "BM039, C16orf60, FLJ13607, FLJ22660" ENSG00000166451 "Centromere protein N" Q96H22 16 81006552-81033114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 64.2;Extravillous trophoblasts: 91.1;Spermatocytes: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052870 Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA052870: AB_2681978" "unprognostic (1.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.15e-1)" "unprognostic (1.76e-2)" "unprognostic (2.15e-1)" "unprognostic (1.76e-2)" "unprognostic (3.69e-3)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (2.36e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.02e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.34e-2)" "unprognostic (7.42e-2)" "unprognostic (1.41e-2)" "unprognostic (7.99e-2)" 5.1 5.0 3.2 7.9 4.0 37.4 3.6 3.1 4.9 2.8 2.1 8.0 7.8 2.3 3.1 7.5 1.6 3.1 5.7 3.3 3.1 5.4 9.0 3.3 11.0 3.8 4.0 1.5 5.2 8.6 1.6 8.9 3.4 18.7 7.6 1.4 2.5 2.7 4.5 3.8 6.4 6.4 2.7 4.3 5.2 11.2 3.9 18.1 2.8 2.6 12.0 6.0 2.8 5.8 86.2 81.0 64.9 58.4 16.9 15.1 82.6 97.5 59.3 137.0 59.6 150.8 64.6 48.1 52.4 48.9 62.7 69.9 53.1 61.5 172.9 29.3 47.9 43.0 63.3 100.9 9.6 64.6 80.4 14.0 6.6 123.3 40.8 18.0 62.6 59.1 83.6 65.9 66.9 160.1 78.0 79.6 69.7 37.2 45.4 90.9 64.5 51.3 22.5 58.6 43.2 38.9 140.3 31.8 40.1 38.9 76.2 34.0 38.5 97.7 101.1 66.8 96.8 46.4 112.1 186.8 45.8 43.7 85.8 0.9 1.4 2.4 2.1 2.8 2.0 1.6 2.7 1.5 6.6 5.9 1.3 1.5 1.7 3.6 3.1 2.2 7.9 2.0 3.2 4.0 3.1 4.9 3.3 3.1 3.8 4.0 3.4 2.7 3.9 5.8 2.8 0.0 4.8 1.0 10.2 24.0 15.7 9.6 14.8 1.0 6.0 7.0 4.8 5.7 5.8 3.7 0.0 47.1 10.0 7.4 0.0 5.7 41.8 4.5 3.8 5.8 1.2 64.2 1.9 6.5 91.1 9.7 11.7 6.4 6.3 13.2 6.8 6.3 27.2 0.0 1.1 12.8 12.2 9.7 20.2 40.9 2.8 10.4 7.2 1.0 4.4 0.8 0.0 0.5 6.1 5.1 4.0 3.4 34.7 13.6 5.1 8.8 1.8 0.4 0.0 7.1 10.0 52.3 39.1 32.7 16.3 27.2 10.9 6.3 22.0 16.6 CENPW "C6orf173, CUG2" ENSG00000203760 "Centromere protein W" Q5EE01 6 126340115-126348875 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.6;testis: 39.5" "Cell type enhanced" "Detected in many" "Early spermatids: 329.7;Extravillous trophoblasts: 155.9;Spermatocytes: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA067285 Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA067285: AB_2685818" "unprognostic (3.51e-3)" "unprognostic (2.35e-1)" "unprognostic (3.26e-3)" "unprognostic (9.61e-3)" "unprognostic (3.78e-1)" "unprognostic (9.80e-3)" "prognostic unfavorable (1.21e-5)" "unprognostic (1.11e-2)" "unprognostic (2.82e-2)" "unprognostic (9.07e-2)" "unprognostic (5.86e-3)" "unprognostic (1.08e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.07e-1)" "unprognostic (1.85e-1)" "unprognostic (2.30e-1)" "unprognostic (1.22e-1)" 8.2 4.3 2.5 12.8 2.3 50.6 6.6 2.0 3.5 14.4 1.4 15.0 8.3 21.6 7.0 23.1 9.2 5.4 1.7 4.2 2.0 3.4 3.6 4.9 15.5 1.9 2.0 4.1 2.1 2.8 2.5 7.8 1.7 6.3 17.5 1.6 8.5 4.4 3.0 8.3 10.8 16.1 1.9 6.8 6.3 39.5 2.0 27.4 2.5 1.9 20.5 6.6 10.9 2.4 73.4 49.0 94.7 82.9 10.3 10.4 81.2 60.0 43.6 81.3 98.3 148.0 50.1 86.8 48.8 38.3 128.7 88.0 78.0 94.3 114.6 94.0 140.2 84.7 141.4 166.3 3.4 123.8 59.1 6.4 10.0 69.1 51.2 23.1 88.3 116.8 144.1 56.5 69.6 119.3 103.1 204.4 60.5 64.0 74.3 107.7 63.2 62.6 38.0 33.0 99.1 44.0 50.8 46.5 67.4 76.9 43.7 119.5 48.0 76.6 78.3 104.6 163.7 36.9 72.7 156.8 45.9 147.0 92.8 3.2 16.9 2.3 2.0 20.3 0.6 6.0 4.4 4.3 15.9 3.5 3.4 2.7 2.9 6.9 14.1 18.9 12.0 5.9 2.5 2.3 2.0 3.5 4.2 2.0 1.9 2.0 1.7 1.9 2.0 2.4 2.5 0.0 2.6 1.0 18.6 38.0 13.4 54.3 6.2 1.3 10.3 18.7 0.3 11.5 29.4 1.8 2.1 52.2 6.1 23.5 5.9 16.6 329.7 18.0 26.5 11.0 7.8 75.1 23.7 17.9 155.9 25.1 17.3 12.7 13.4 31.4 10.8 6.0 63.6 3.3 22.0 27.1 42.7 15.6 40.1 39.3 19.3 19.3 8.8 1.0 12.6 3.1 3.1 1.0 2.4 17.2 10.6 9.1 38.6 24.7 18.1 1.6 7.0 1.4 0.0 6.4 18.1 148.3 83.8 60.9 29.0 21.2 8.6 11.4 51.7 35.8 CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.0" "Group enriched" "Detected in many" 8 "Early spermatids: 1061.4;Late spermatids: 1606.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 32.0;RH-30: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (9.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.11e-3)" "unprognostic (1.43e-2)" "unprognostic (7.99e-2)" "unprognostic (4.48e-3)" "unprognostic (3.37e-2)" "unprognostic (1.39e-3)" "unprognostic (3.50e-2)" "unprognostic (4.46e-3)" "unprognostic (1.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" 11.3 3.9 5.0 2.7 5.4 1.7 9.5 7.1 5.8 8.3 11.9 7.8 2.0 8.5 8.2 4.3 8.3 7.0 8.0 7.4 5.1 5.6 3.2 7.4 2.5 5.8 5.7 8.2 4.6 8.7 8.3 7.2 4.2 7.2 3.1 25.4 3.0 7.9 8.8 3.3 2.9 8.0 3.4 8.8 4.2 49.0 5.5 2.8 7.1 14.0 1.7 5.4 5.9 3.4 5.0 10.5 13.3 3.8 6.9 14.0 0.4 4.5 7.7 5.5 5.0 1.5 2.0 1.6 4.3 9.8 15.5 0.6 2.9 2.9 7.8 2.6 4.8 0.3 4.7 1.9 2.9 0.6 0.2 8.4 4.8 5.2 1.6 11.0 16.8 2.7 0.3 5.0 32.0 0.7 5.3 0.4 1.3 1.1 4.4 1.5 75.9 0.4 6.0 0.3 3.5 7.4 4.7 0.5 3.6 11.4 3.8 0.4 7.9 14.3 8.2 3.9 6.7 2.3 2.1 0.2 4.4 0.2 5.3 1.3 0.4 0.4 0.3 0.2 0.6 0.3 0.8 0.3 0.2 0.8 0.5 0.3 1.3 0.8 0.2 1.4 0.5 0.1 5.0 5.4 7.1 5.8 7.4 5.1 5.8 5.7 4.2 3.4 5.5 3.4 39.7 9.6 35.8 83.6 1.1 2.5 2.9 2.2 2.2 36.7 2.7 5.5 28.3 4.3 15.3 1.8 20.9 0.7 0.8 1.5 1.9 7.4 1061.4 15.3 15.8 25.4 1.8 0.4 117.4 4.7 1.5 12.4 1.5 3.3 2.5 11.2 19.2 0.2 1.8 1.7 103.8 0.3 0.0 0.8 11.3 1606.0 24.8 2.3 14.2 99.3 0.0 14.7 1.0 29.7 6.6 4.4 0.5 19.9 0.4 1.5 0.0 4.3 23.7 154.3 13.1 43.7 12.5 40.6 16.5 2.4 1.6 0.1 2.5 3.1 1.5 1.3 CEP85L "bA57K17.2, C6orf204, NY-BR-15" ENSG00000111860 "Centrosomal protein 85 like" Q5SZL2 6 118460772-118710075 "Disease related genes, Predicted intracellular proteins" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 29.9" "Cell type enhanced" "Detected in many" "Astrocytes: 266.1;Early spermatids: 445.2;Late spermatids: 742.5;Oligodendrocyte precursor cells: 251.9;Oligodendrocytes: 189.4" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029137, HPA029138, HPA029139" Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "HPA029137: AB_10600657, HPA029138: AB_10600874, HPA029139: AB_10601220" "unprognostic (3.25e-2)" "unprognostic (1.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.82e-1)" "unprognostic (2.19e-2)" "unprognostic (2.34e-1)" "unprognostic (7.24e-2)" "unprognostic (1.01e-2)" "unprognostic (8.37e-2)" "unprognostic (2.03e-1)" "unprognostic (1.39e-3)" "unprognostic (8.45e-2)" "unprognostic (2.87e-5)" "unprognostic (2.72e-3)" "unprognostic (2.44e-1)" "unprognostic (1.64e-1)" "unprognostic (1.85e-2)" 3.3 5.2 4.0 7.1 5.5 11.5 2.5 11.7 5.2 3.9 0.0 2.6 1.8 4.1 2.1 3.0 3.8 3.2 4.6 3.8 5.2 1.4 2.2 3.3 13.5 5.1 7.4 7.5 2.6 3.5 5.1 4.2 5.5 2.2 2.4 3.3 4.5 2.0 8.5 1.3 4.1 3.1 4.0 7.7 8.0 29.9 6.8 19.1 2.2 11.8 9.7 5.2 2.6 5.4 1.3 1.1 6.5 3.7 3.5 6.5 25.7 3.4 5.1 3.0 3.4 0.2 0.3 6.6 1.0 5.0 2.5 1.7 2.9 4.9 5.5 3.6 3.4 8.8 2.0 0.8 2.8 0.6 2.5 3.8 2.6 3.7 4.0 6.0 4.4 9.5 8.7 6.1 5.0 1.0 16.0 4.0 2.0 0.2 1.8 3.8 5.1 1.5 3.6 2.9 4.0 2.3 2.6 0.1 5.0 5.2 0.8 3.3 3.6 4.8 2.7 4.2 5.6 7.8 6.1 6.0 4.0 2.9 5.0 1.5 10.7 9.0 6.6 11.6 6.7 3.4 5.4 5.4 5.5 4.6 7.1 5.9 15.7 6.9 11.2 2.6 4.7 4.0 4.0 5.5 11.7 5.2 3.8 5.2 5.1 7.4 5.5 4.0 6.8 5.4 24.1 6.4 4.6 266.1 26.3 6.9 10.7 10.6 9.6 31.6 4.5 7.1 33.9 0.0 3.5 3.7 10.4 26.7 35.5 0.2 1.9 3.7 445.2 7.5 43.2 25.8 3.0 2.5 156.1 4.3 5.9 23.4 33.1 16.6 8.8 12.5 14.6 6.5 8.4 33.7 147.1 0.6 2.0 25.7 16.7 742.5 32.0 24.0 23.2 80.6 22.9 4.7 19.6 251.9 189.4 9.4 1.2 29.0 28.7 7.1 0.0 2.1 5.2 9.8 19.7 53.4 32.2 38.2 49.7 3.5 4.8 22.2 48.3 48.3 0.6 8.1 CFAP251 "CaM-IP4, MGC33630, WDR66" ENSG00000158023 "Cilia and flagella associated protein 251" Q8TBY9 12 121918592-122003927 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.3;testis: 19.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.7;Fibroblasts: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 31.8;hTCEpi: 30.8;hTERT-HME1: 19.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039902, HPA040005" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA039902: AB_10795236, HPA040005: AB_10795160" "unprognostic (4.92e-3)" "unprognostic (9.05e-2)" "unprognostic (7.99e-3)" "prognostic favorable (3.11e-4)" "unprognostic (5.58e-3)" "unprognostic (6.89e-3)" "unprognostic (1.44e-2)" "unprognostic (2.45e-1)" "unprognostic (2.89e-1)" "unprognostic (2.34e-1)" "unprognostic (7.72e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-2)" "unprognostic (4.29e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" 1.1 0.8 1.6 0.3 2.4 0.1 1.3 1.3 1.7 3.5 13.2 0.2 0.1 1.9 4.7 0.3 22.3 1.2 1.3 2.4 3.9 2.7 1.4 3.0 0.6 5.5 6.6 2.2 1.7 2.9 6.5 0.9 3.6 0.7 0.1 4.6 1.1 1.6 0.3 1.5 0.2 0.6 2.7 1.7 0.4 19.9 4.1 0.5 4.7 0.4 0.9 0.3 1.3 1.6 4.7 0.4 0.4 0.2 0.5 0.5 0.5 0.3 2.5 1.2 3.0 0.3 1.4 0.2 3.7 0.2 0.7 0.9 0.3 31.8 4.4 0.2 0.5 0.2 0.6 0.3 3.7 0.1 8.6 1.8 30.8 2.4 19.9 0.7 1.3 0.5 7.5 0.1 1.9 0.9 0.3 0.6 0.4 0.4 0.2 0.4 0.8 0.0 5.4 0.5 2.5 0.1 0.2 0.1 0.2 0.8 0.9 0.1 1.0 2.5 3.9 0.5 0.5 0.5 0.2 3.8 2.9 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.0 1.6 2.4 1.3 1.7 2.4 3.9 5.5 6.6 3.6 2.7 4.1 1.6 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 CFAP36 "BARTL1, CCDC104, MGC15407" ENSG00000163001 "Cilia and flagella associated protein 36" Q96G28 2 55519604-55545079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1342.4;Late spermatids: 262.5;Spermatocytes: 346.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008994, HPA017061" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli fibrillar center, Nuclear bodies" Cytosol "HPA008994: AB_2275429, HPA017061: AB_1846129" "unprognostic (8.11e-2)" "unprognostic (3.21e-3)" "unprognostic (1.24e-1)" "unprognostic (3.36e-2)" "unprognostic (7.98e-2)" "unprognostic (3.68e-1)" "unprognostic (4.65e-3)" "unprognostic (7.79e-2)" "unprognostic (1.51e-2)" "unprognostic (1.58e-2)" "unprognostic (3.66e-3)" "unprognostic (7.63e-2)" "unprognostic (8.57e-3)" "unprognostic (4.94e-2)" "unprognostic (3.35e-2)" "unprognostic (1.56e-3)" "unprognostic (2.96e-1)" 39.1 42.7 72.7 20.2 74.8 16.5 48.9 61.8 98.8 49.8 82.8 52.3 15.1 47.1 77.0 21.9 62.3 40.9 35.7 75.0 78.5 63.2 17.7 33.9 21.7 71.8 70.4 58.9 33.6 78.0 106.7 20.6 72.1 41.6 23.2 124.3 28.7 45.0 19.2 18.8 25.2 37.4 65.9 18.2 42.1 145.2 73.6 22.8 78.0 27.1 19.7 40.7 33.6 70.1 59.5 47.3 50.2 66.3 64.4 119.4 30.4 36.6 73.4 54.9 46.6 34.6 21.2 21.3 82.3 48.9 81.9 38.4 39.3 51.4 67.7 51.9 76.2 31.0 43.9 38.1 70.0 59.4 38.4 58.1 82.7 74.0 92.1 146.8 58.9 42.5 40.1 18.2 66.1 44.4 35.7 67.5 25.2 38.7 44.8 27.2 59.7 21.7 112.1 33.7 74.1 36.6 49.4 25.6 68.5 26.2 42.1 19.7 32.5 57.6 33.7 58.5 50.8 29.9 14.2 7.3 94.0 26.7 26.8 15.5 4.3 13.6 18.3 5.0 35.4 16.9 50.6 29.6 5.8 11.7 41.1 26.0 5.2 12.3 6.4 13.5 30.5 15.9 72.7 74.8 61.8 98.8 75.0 78.5 71.8 70.4 72.1 65.9 73.6 70.1 51.3 48.1 30.6 15.7 14.5 0.0 52.6 0.0 22.2 39.6 48.7 77.2 37.9 38.6 27.2 35.0 8.4 14.3 14.8 6.4 92.0 61.9 1342.4 184.4 51.8 42.9 17.0 21.0 51.6 60.7 27.0 44.7 21.9 36.3 39.1 27.1 42.1 10.7 23.6 23.5 41.1 12.2 0.0 8.7 0.0 262.5 75.2 12.8 0.0 14.0 16.9 145.0 16.5 21.6 13.3 37.0 11.5 67.7 11.4 41.3 7.6 146.9 99.1 92.4 59.2 43.0 43.4 346.0 29.8 16.1 0.0 7.8 24.7 36.0 9.9 35.6 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.6;intestine: 42.7;pancreas: 210.7" "Group enriched" "Detected in many" 4 "Ductal cells: 485.4;Ionocytes: 252.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "CACO-2: 29.5;MOLT-4: 98.9;U-266/70: 49.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.0 0.5 4.7 2.0 0.0 0.4 0.7 1.3 8.5 0.0 42.7 36.2 1.1 1.1 0.8 2.2 54.6 0.1 0.3 0.7 2.1 1.6 8.2 0.0 1.1 0.7 0.0 210.7 0.2 0.1 0.6 0.7 2.2 40.7 0.0 21.5 0.5 0.0 1.9 19.9 2.0 1.7 0.0 3.1 1.7 1.0 0.1 0.1 0.0 0.3 0.7 0.0 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 98.9 0.1 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 49.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.7 1.3 0.3 0.7 1.1 0.7 0.7 1.7 1.0 2.9 0.0 6.4 65.6 0.0 0.5 0.0 2.0 2.6 0.0 0.5 0.5 0.0 2.4 55.8 17.8 0.0 0.0 0.0 0.0 45.8 0.0 485.4 3.2 9.6 1.2 0.4 7.2 0.0 2.2 4.5 0.0 0.3 4.1 19.8 1.3 0.1 0.0 0.4 0.0 0.0 1.1 13.9 252.3 0.0 0.0 2.6 0.3 0.1 0.0 1.0 6.7 0.5 0.0 0.5 23.8 14.8 86.4 0.0 0.0 4.0 8.6 0.0 5.6 0.0 0.0 0.0 1.6 2.2 0.5 0.0 0.0 0.0 0.3 0.1 87.3 5.8 CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101787-6180321 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 59.0;pituitary gland: 57.3;testis: 31.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 84.3;Early spermatids: 217.8;Excitatory neurons: 80.4;Horizontal cells: 225.4;Inhibitory neurons: 56.2;Late spermatids: 113.2;Rod photoreceptor cells: 49.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 12.9;U-2 OS: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" 0.2 4.1 31.8 0.2 40.1 0.0 0.1 0.0 59.0 0.4 0.0 1.1 0.2 0.4 0.0 0.3 0.4 0.1 0.4 34.3 13.6 2.4 0.1 0.3 0.0 3.9 11.1 0.5 0.4 0.9 57.3 0.0 4.4 0.9 0.2 7.9 0.2 2.2 0.2 0.3 0.4 0.1 0.9 0.1 1.0 31.8 10.2 0.3 0.1 0.0 0.0 0.7 0.6 31.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 1.2 0.0 0.1 0.2 1.1 0.0 0.0 0.0 0.0 12.9 0.2 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.8 40.1 0.0 59.0 34.3 13.6 3.9 11.1 4.4 0.9 10.2 31.1 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 0.0 84.3 0.1 0.3 2.1 0.0 0.0 3.7 12.5 0.0 0.1 0.2 0.0 0.0 217.8 0.0 0.2 0.6 0.0 0.0 80.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 225.4 56.2 0.0 0.0 0.0 0.3 113.2 0.9 0.1 0.0 2.8 0.0 2.0 0.0 4.5 3.7 0.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 49.9 0.0 0.2 0.5 4.5 17.8 0.0 0.4 0.0 0.1 0.1 0.0 0.0 CHD8 "DUPLIN, HELSNF1, KIAA1564" ENSG00000100888 "Chromodomain helicase DNA binding protein 8" Q9HCK8 14 21385194-21456126 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052186, HPA076133" Enhanced Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA052186: AB_2681754, HPA076133: " "unprognostic (3.45e-1)" "unprognostic (9.71e-2)" "unprognostic (3.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.31e-2)" "unprognostic (9.22e-2)" "prognostic favorable (8.35e-4)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (2.54e-3)" "unprognostic (2.88e-1)" "unprognostic (9.24e-2)" "unprognostic (2.51e-1)" "unprognostic (8.07e-3)" 12.5 11.9 11.2 13.5 12.5 35.3 14.8 16.3 13.2 12.4 10.5 14.0 9.4 14.8 11.1 14.9 12.9 10.1 12.0 11.1 12.2 11.7 9.6 13.7 18.0 11.4 11.6 17.1 13.6 22.3 13.1 11.7 11.1 13.2 12.3 14.8 13.6 12.1 15.7 22.3 14.7 14.8 11.5 15.8 14.2 12.9 12.5 25.4 14.8 12.7 17.5 12.8 12.9 13.6 31.2 39.6 43.6 20.7 27.7 23.6 24.9 24.4 28.4 36.5 35.4 35.0 26.3 51.4 14.8 33.1 28.4 37.2 54.9 35.1 46.0 39.3 24.2 46.3 27.6 43.5 25.7 64.6 40.4 32.8 27.2 40.9 29.7 28.6 33.4 40.2 32.4 26.7 28.0 33.9 46.1 26.0 33.4 30.9 34.3 42.0 32.9 17.4 27.3 57.9 30.9 30.7 37.5 29.8 21.8 39.7 20.7 30.5 36.4 29.2 23.0 17.8 29.1 30.3 38.4 50.3 12.1 23.2 29.6 9.1 3.8 9.8 5.5 3.8 6.4 4.2 4.9 5.6 2.7 11.2 5.0 4.4 7.9 7.8 6.7 6.1 4.7 2.7 11.2 12.5 16.3 13.2 11.1 12.2 11.4 11.6 11.1 11.5 12.5 13.6 27.6 38.5 56.3 27.4 32.2 12.6 11.3 15.9 23.3 33.3 21.9 22.6 19.6 24.3 32.6 33.1 27.1 14.7 40.0 16.8 1.9 21.8 3.4 32.5 37.9 25.5 27.1 27.8 41.0 23.6 12.3 24.0 27.5 39.5 28.4 41.7 13.9 14.9 17.5 23.5 40.2 16.0 8.2 20.1 9.3 4.1 16.1 25.3 10.6 20.6 27.1 18.9 32.0 29.7 33.1 26.5 13.9 17.7 32.4 16.1 12.0 7.4 28.8 24.3 0.0 32.1 26.2 29.2 25.1 24.6 16.6 12.3 31.4 34.1 16.8 12.7 CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 72.1;prostate: 29.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.5;Inhibitory neurons: 14.8;Prostatic glandular cells: 2.4;Theca cells: 3.4" "Cancer enriched" "Detected in single" 421 "prostate cancer: 30.2" "Region enhanced" "Detected in many" "thalamus: 72.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (3.19e-1)" "unprognostic (6.19e-2)" "unprognostic (6.29e-3)" "unprognostic (1.19e-2)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (7.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" 0.0 0.5 15.8 0.2 5.5 0.9 1.4 38.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.0 0.0 0.0 0.2 0.1 15.7 21.5 0.0 0.2 0.0 0.3 0.0 3.5 29.0 0.0 3.7 0.0 0.0 0.1 0.2 0.2 0.0 2.3 0.1 0.0 0.0 72.1 2.9 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 15.8 5.5 38.1 2.9 0.7 8.0 15.7 21.5 3.5 2.3 72.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 CHST2 C6ST ENSG00000175040 "Carbohydrate sulfotransferase 2" Q9Y4C5 3 143119771-143124014 "Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.4" "Cell type enhanced" "Detected in many" "Muller glia cells: 114.4;NK-cells: 233.8;Plasma cells: 79.3;Sertoli cells: 92.1;Theca cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.3;NK-cell: 4.9;non-classical monocyte: 11.4" "Group enriched" "Detected in many" 5 "monocytes: 11.4;NK-cells: 4.9" "Cell line enhanced" "Detected in many" "ASC diff: 57.7;ASC TERT1: 58.8;HEL: 48.2;HHSteC: 118.4;HMC-1: 55.4;HSkMC: 62.3;U-266/70: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013620 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA013620: AB_2668861" "unprognostic (1.55e-2)" "unprognostic (2.20e-1)" "unprognostic (7.64e-3)" "unprognostic (2.75e-1)" "unprognostic (8.97e-3)" "unprognostic (2.83e-1)" "unprognostic (2.70e-2)" "unprognostic (2.06e-1)" "unprognostic (2.76e-1)" "unprognostic (4.11e-2)" "unprognostic (8.96e-3)" "unprognostic (9.15e-2)" "unprognostic (1.31e-2)" "unprognostic (7.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.58e-3)" "unprognostic (1.34e-1)" 7.7 2.7 17.8 8.1 13.7 16.8 6.3 16.7 14.6 5.7 6.0 3.0 2.1 8.4 1.4 1.1 2.1 1.7 5.6 9.7 13.4 8.4 1.3 7.5 7.7 31.0 18.4 4.9 1.3 0.9 6.9 10.3 28.1 7.4 1.1 11.0 2.7 9.9 1.6 4.4 7.5 3.7 21.4 18.2 3.4 1.7 28.7 14.5 6.7 0.8 5.4 7.1 7.6 48.4 0.0 0.3 3.1 2.6 57.7 58.8 0.2 3.3 9.5 2.3 2.1 0.0 0.0 0.6 2.0 2.3 3.1 0.1 2.3 8.2 1.2 0.8 1.5 48.2 0.1 0.0 118.4 1.2 55.4 62.3 9.7 3.1 10.1 3.6 3.6 7.2 5.5 2.9 15.4 0.0 9.1 12.2 16.5 0.0 8.0 0.5 1.0 0.1 1.7 2.2 3.7 0.0 0.7 0.0 5.6 2.9 0.0 1.9 12.3 7.0 4.1 9.5 13.9 52.4 0.8 3.3 13.8 9.3 37.4 0.7 0.5 0.7 0.3 4.3 0.0 1.1 0.1 0.2 1.6 0.8 0.6 0.5 0.3 4.9 11.4 0.1 0.5 0.9 17.8 13.7 16.7 14.6 9.7 13.4 31.0 18.4 28.1 21.4 28.7 48.4 11.3 0.0 0.0 3.6 17.7 2.4 7.3 2.5 0.0 25.0 2.8 2.7 1.4 0.0 1.8 3.7 2.1 0.6 41.9 0.0 0.0 0.4 0.2 5.7 29.8 9.4 0.0 39.1 6.8 0.2 0.6 14.4 2.0 6.5 11.4 12.5 3.6 0.4 2.8 1.7 8.1 0.0 0.0 10.3 32.2 1.3 12.8 20.2 17.8 1.0 13.6 114.4 233.8 2.5 6.1 5.9 0.0 2.2 79.3 13.1 0.0 0.0 0.1 23.8 92.1 0.8 20.2 0.0 2.2 0.1 0.6 1.0 9.8 58.1 1.3 14.8 CHST9 "GALNAC-4-ST2, GALNAC4ST-2" ENSG00000154080 "Carbohydrate sulfotransferase 9" Q7L1S5 18 26906481-27185308 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 13.8" "Cell type enhanced" "Detected in many" "Club cells: 115.2;Muller glia cells: 69.2;Oligodendrocyte precursor cells: 167.4;Respiratory ciliated cells: 311.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.3;Hep G2: 13.8;RPTEC TERT1: 41.8;SCLC-21H: 9.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA011393 Uncertain "Intracellular and membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA011393: AB_1846733" "unprognostic (9.24e-3)" "unprognostic (1.13e-2)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (4.53e-3)" "unprognostic (9.98e-3)" "unprognostic (9.21e-3)" "unprognostic (7.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.04e-2)" "unprognostic (3.54e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (3.93e-3)" 0.0 0.2 0.8 0.1 0.9 0.0 2.9 0.7 2.4 2.8 0.0 1.6 0.2 0.1 0.4 1.6 10.3 3.1 2.6 2.7 1.2 1.6 8.2 4.3 0.0 3.5 2.3 0.0 9.3 0.0 1.9 0.0 1.2 3.5 0.2 7.3 13.8 1.8 0.2 0.1 0.3 0.1 2.0 5.7 0.7 6.9 1.2 1.0 0.0 0.9 0.6 1.5 0.7 1.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 41.8 0.0 9.0 0.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.7 2.4 2.7 1.2 3.5 2.3 1.2 2.0 1.2 1.9 0.1 0.0 2.7 24.8 0.0 0.6 32.6 56.6 4.6 1.3 8.2 8.0 9.2 35.8 115.2 5.5 0.0 0.4 0.1 0.0 11.7 13.0 7.1 49.9 0.7 0.3 3.5 0.0 10.1 0.6 0.1 4.2 0.0 1.8 5.1 0.1 0.0 10.7 0.3 0.0 29.3 0.1 22.4 0.0 0.0 4.4 0.6 0.5 7.2 1.0 0.0 69.2 0.0 167.4 1.0 1.3 0.0 0.4 0.0 8.9 0.0 0.3 311.6 3.2 0.0 3.2 3.7 0.9 1.3 4.7 0.0 0.3 0.4 0.0 0.0 40.3 CHSY3 "CHSY-2, CSS3" ENSG00000198108 "Chondroitin sulfate synthase 3" Q70JA7 5 129904465-130186634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 509.1;Inhibitory neurons: 349.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 2.0;basal ganglia: 2.6;cerebral cortex: 2.9;hippocampal formation: 2.5;white matter: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.1;ASC TERT1: 11.5;HSkMC: 7.6;TIME: 7.4;U-138 MG: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044612 Uncertain "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA044612: AB_10795883" "unprognostic (3.43e-2)" "unprognostic (6.28e-3)" "unprognostic (1.76e-2)" "unprognostic (5.83e-2)" "unprognostic (5.88e-2)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (9.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.08e-6)" "unprognostic (5.22e-3)" "unprognostic (9.93e-2)" "unprognostic (4.61e-3)" "unprognostic (1.74e-2)" 6.0 0.5 2.0 1.0 2.6 0.0 2.8 0.0 2.9 4.5 0.0 0.7 0.5 1.5 0.1 0.6 1.1 2.8 1.3 2.5 0.2 0.2 1.7 1.8 0.5 0.0 0.4 0.3 0.3 0.4 0.3 2.2 0.0 0.5 0.5 1.0 0.5 0.6 1.0 1.3 0.5 2.0 0.2 0.7 0.5 0.7 0.4 0.2 1.2 0.5 0.4 1.7 1.9 1.1 0.0 0.1 1.2 0.0 13.1 11.5 1.0 3.0 0.1 0.4 0.4 0.0 0.1 0.0 0.3 4.6 0.0 0.0 0.0 0.1 0.0 0.0 1.6 1.9 5.6 0.5 1.2 0.0 0.0 7.6 0.0 0.1 1.2 0.6 3.2 0.0 0.0 1.9 5.2 0.0 0.0 0.0 0.7 0.0 1.2 0.4 5.7 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.3 1.1 0.2 0.5 7.4 14.2 3.0 0.2 2.0 0.0 0.0 0.0 0.3 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.6 0.0 2.9 2.5 0.2 0.0 0.4 0.0 0.2 0.4 1.1 2.0 9.6 1.1 20.2 0.0 0.5 0.0 0.0 1.2 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.9 0.5 14.8 2.4 0.0 0.0 509.1 0.0 0.1 2.9 0.0 0.3 0.0 4.1 3.6 1.8 1.9 0.0 349.5 0.0 0.0 1.3 0.7 0.1 1.2 0.1 3.6 87.1 0.0 1.3 0.0 76.9 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.1 6.6 0.9 6.3 1.6 0.7 0.3 0.3 0.4 0.2 0.6 0.0 0.1 CIBAR1 "FAM92A, FAM92A1, FLJ38979" ENSG00000188343 "CBY1 interacting BAR domain containing 1" A1XBS5 8 93698561-93731527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 110.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 13.3;Extravillous trophoblasts: 14.1;Fibroblasts: 8.4;Hofbauer cells: 6.4;Syncytiotrophoblasts: 3.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034760, HPA058942" Enhanced Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA034760: AB_10599947, HPA058942: AB_2732628" "unprognostic (2.65e-3)" "unprognostic (6.81e-2)" "unprognostic (2.48e-3)" "unprognostic (2.44e-1)" "unprognostic (1.62e-2)" "unprognostic (2.93e-1)" "unprognostic (3.56e-1)" "unprognostic (3.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (2.28e-3)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "unprognostic (6.85e-3)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (3.07e-2)" 14.3 23.9 17.5 5.6 18.8 3.5 10.9 18.6 25.0 16.5 22.9 14.2 3.2 16.0 26.2 5.0 13.1 14.1 25.3 17.8 16.2 20.2 18.5 9.9 5.7 13.4 14.5 18.0 21.1 21.5 20.8 10.1 13.3 12.1 5.9 14.1 5.7 11.6 10.3 6.6 7.7 15.0 12.9 5.7 9.8 110.2 17.1 5.0 14.5 11.1 3.1 14.6 9.3 17.4 37.8 20.0 52.9 54.6 55.8 78.9 14.0 34.2 49.8 45.2 43.5 3.5 8.6 3.2 42.7 50.7 52.0 26.6 54.0 32.5 41.0 1.2 29.5 21.5 20.8 18.7 64.1 1.0 5.5 50.4 14.3 44.3 36.0 64.9 49.0 18.1 13.4 1.7 35.8 14.2 23.8 4.1 22.2 0.8 1.1 2.3 39.7 0.8 35.3 8.7 15.3 18.7 24.4 0.5 41.6 23.7 8.2 11.8 27.2 44.2 17.4 46.3 28.0 2.6 2.7 1.2 38.8 3.0 15.8 0.1 1.7 0.0 0.1 1.2 0.2 0.4 0.4 0.1 2.9 0.0 0.1 0.3 0.0 1.3 0.1 0.3 0.8 0.5 17.5 18.8 18.6 25.0 17.8 16.2 13.4 14.5 13.3 12.9 17.1 17.4 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 14.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CIP2A KIAA1524 ENSG00000163507 "Cellular inhibitor of PP2A" Q8TCG1 3 108549864-108589644 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.5;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 8.0;Exocrine glandular cells: 7.3;Extravillous trophoblasts: 12.9;Granulosa cells: 25.3;Hofbauer cells: 8.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039570 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA039570: AB_10796329" "unprognostic (2.02e-1)" "unprognostic (1.54e-2)" "unprognostic (2.31e-3)" "prognostic unfavorable (6.24e-5)" "unprognostic (3.10e-2)" "unprognostic (1.07e-2)" "unprognostic (1.91e-7)" "unprognostic (2.80e-3)" "unprognostic (2.53e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.18e-4)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (9.11e-3)" "unprognostic (3.73e-1)" "unprognostic (2.11e-1)" "unprognostic (1.25e-1)" 1.1 1.1 0.3 3.4 0.6 7.5 1.4 0.9 0.8 0.9 0.1 1.9 1.2 1.8 0.6 1.7 0.9 1.2 0.7 0.6 0.5 1.0 0.7 1.4 6.7 0.2 0.9 1.9 0.4 0.6 0.7 2.1 0.2 1.8 2.7 2.6 0.6 0.8 0.6 1.2 1.7 1.5 0.0 2.3 1.2 5.7 0.1 6.9 1.2 0.7 5.2 2.0 0.9 0.4 42.2 12.2 33.9 21.8 1.4 3.2 13.8 31.1 14.7 36.2 41.9 15.0 18.5 27.6 10.4 11.4 27.7 20.9 11.7 11.0 65.8 8.8 11.3 33.9 17.4 11.3 0.5 21.8 23.2 1.4 2.3 28.4 11.5 5.9 16.3 12.7 21.1 44.5 36.1 8.7 26.7 19.2 35.0 15.8 20.8 30.1 31.2 15.3 11.0 11.5 16.4 21.6 22.9 9.0 12.7 19.7 15.3 15.6 12.2 37.0 41.7 11.3 38.3 10.2 12.1 46.1 16.4 23.2 38.6 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.6 0.9 0.8 0.6 0.5 0.2 0.9 0.2 0.0 0.1 0.4 1.2 9.6 1.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 1.9 1.3 0.0 0.0 2.5 3.7 0.0 8.0 1.8 0.0 1.9 2.8 0.0 2.5 2.8 2.6 0.0 0.0 0.0 7.3 12.9 3.0 0.0 2.7 3.8 25.3 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.4 0.0 0.0 2.4 1.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.4 1.7 5.4 0.0 0.0 CIT "CITK, CRIK, KIAA0949, STK21" ENSG00000122966 "Citron rho-interacting serine/threonine kinase" O14578 12 119685791-119877320 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 72.8;Excitatory neurons: 147.0;Inhibitory neurons: 139.8;Oligodendrocyte precursor cells: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019082, HPA048812, HPA075506" Uncertain Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA019082: AB_1846803, HPA048812: AB_2680528, HPA075506: AB_2686752" "unprognostic (5.64e-2)" "unprognostic (5.00e-2)" "unprognostic (8.16e-2)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (3.61e-6)" "unprognostic (6.02e-2)" "unprognostic (7.78e-2)" "unprognostic (4.42e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-2)" "unprognostic (2.55e-3)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (1.70e-1)" "unprognostic (3.30e-1)" 0.7 2.2 13.5 1.6 26.2 6.3 0.6 0.0 19.9 0.9 0.0 2.1 1.2 0.4 0.0 2.5 0.5 0.5 0.6 15.2 5.4 2.5 0.3 1.8 1.5 0.2 5.0 0.3 0.2 0.1 1.6 1.4 0.4 0.5 2.5 3.4 0.8 0.2 0.5 1.6 1.9 0.9 0.9 3.0 2.2 4.8 14.2 6.8 0.6 0.3 2.3 0.5 1.3 6.6 26.2 20.6 21.7 15.3 2.4 6.3 10.4 22.0 19.1 21.8 16.6 14.5 10.3 18.4 10.0 14.2 9.3 14.6 14.4 9.5 32.1 13.6 7.5 25.7 13.2 7.1 0.3 12.7 20.6 0.9 1.2 23.7 14.8 7.3 15.5 19.9 14.5 15.2 19.5 12.2 22.4 14.0 10.4 8.7 12.5 19.3 39.8 6.3 5.0 11.1 15.5 8.4 31.9 6.5 16.0 9.6 23.2 10.6 11.5 21.9 21.4 17.2 22.7 9.9 12.6 14.2 16.8 12.5 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.5 26.2 0.0 19.9 15.2 5.4 0.2 5.0 0.4 0.9 14.2 6.6 4.1 6.4 13.0 8.5 1.2 3.3 0.7 1.0 0.6 8.2 1.8 1.5 1.8 0.0 5.6 9.2 87.6 3.5 0.6 1.1 0.0 0.2 72.8 2.4 2.1 2.7 1.8 12.8 147.0 0.8 4.8 2.2 3.1 3.6 1.3 10.5 1.1 0.7 3.6 0.0 139.8 4.4 6.1 3.7 0.8 44.1 1.2 2.0 3.6 7.5 0.0 15.4 1.0 82.4 18.7 0.2 0.1 1.2 4.1 0.4 0.8 7.5 1.7 15.2 0.0 0.6 3.3 33.2 4.2 7.7 1.3 1.0 2.2 4.3 4.4 1.0 CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 67.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.9;Granulosa cells: 88.6;Spermatocytes: 151.7;Spermatogonia: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA008410, HPA027821" Enhanced Enhanced "Microtubules,Mitotic spindle,Centrosome" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Centrosome "HPA008410: AB_1846832, HPA027821: AB_10602208" "unprognostic (1.85e-1)" "unprognostic (2.09e-3)" "unprognostic (2.44e-2)" "unprognostic (4.07e-3)" "unprognostic (1.39e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.30e-2)" "unprognostic (6.60e-3)" "prognostic unfavorable (1.90e-5)" "unprognostic (2.01e-2)" "unprognostic (5.20e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" 6.0 6.4 3.7 10.0 3.8 67.8 5.7 10.8 5.3 3.2 1.3 8.9 12.1 5.1 4.4 10.4 3.5 4.1 6.0 3.2 4.1 5.1 4.0 5.3 19.4 4.8 3.8 3.2 1.5 4.3 4.5 10.6 5.2 5.6 9.5 7.7 4.6 4.2 2.9 13.9 9.5 8.5 3.3 9.4 5.4 32.5 3.7 33.7 6.3 3.4 20.2 7.2 5.0 3.1 77.6 40.0 155.7 76.4 19.7 19.5 39.6 124.7 70.7 137.4 87.2 59.7 92.3 142.5 19.3 89.2 65.7 86.2 107.6 61.7 188.8 103.0 90.4 129.8 42.6 41.4 8.6 129.7 50.4 14.5 24.6 64.5 83.3 41.2 84.0 62.0 55.3 58.1 152.8 36.0 91.2 64.8 92.2 116.6 42.4 86.2 88.6 62.6 42.1 40.9 47.6 62.4 68.9 49.0 37.1 78.7 54.4 61.7 56.7 38.7 60.9 62.0 124.1 33.4 56.3 173.9 27.3 67.3 105.7 86.0 14.1 22.0 10.3 21.0 9.3 25.3 15.7 12.8 15.8 33.0 12.0 10.4 4.3 5.8 28.7 32.8 33.6 10.0 3.7 3.8 10.8 5.3 3.2 4.1 4.8 3.8 5.2 3.3 3.7 3.1 6.7 6.4 2.8 5.2 41.2 15.0 4.5 32.8 22.2 13.1 11.2 13.2 10.8 2.8 11.4 1.8 6.2 44.3 30.9 7.5 9.8 4.9 41.3 19.4 16.1 12.7 7.2 122.9 10.3 6.0 38.1 12.1 10.7 10.1 16.5 88.6 17.5 5.5 31.8 1.7 12.4 13.6 20.3 24.5 13.7 51.7 7.5 18.5 0.0 6.5 22.9 12.9 5.2 3.5 2.0 2.6 4.6 17.0 30.8 3.7 6.3 9.4 3.7 6.6 6.6 7.6 12.1 151.7 87.5 41.3 15.3 10.0 27.1 29.6 17.9 3.9 CKAP5 "ch-TOG, KIAA0097, TOG, TOGp" ENSG00000175216 "Cytoskeleton associated protein 5" Q14008 11 46743048-46846308 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 119.7;Spermatocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039377, HPA040375" Supported Approved "Nucleoli,Nucleoli rim,Plasma membrane,Centrosome" NA Yes 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centrosome" "Nucleoli, Nucleoli rim" "HPA039377: AB_10805477, HPA040375: AB_10794739" "unprognostic (8.00e-2)" "unprognostic (7.35e-2)" "unprognostic (2.35e-1)" "unprognostic (4.12e-2)" "unprognostic (1.91e-1)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (6.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-2)" "unprognostic (4.30e-3)" "unprognostic (3.77e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (4.69e-2)" 12.8 30.7 15.9 15.1 19.5 25.9 14.9 30.8 24.3 11.7 5.2 18.5 12.6 15.7 12.2 13.0 11.5 12.2 21.3 21.4 18.0 11.5 45.5 10.4 18.4 21.0 17.4 27.8 9.0 21.2 12.5 17.3 22.9 15.9 17.2 57.0 9.1 13.2 37.8 13.7 12.3 19.3 17.5 11.9 16.1 33.0 20.2 36.4 9.6 28.8 18.5 13.5 10.8 24.6 104.7 95.8 212.6 90.8 48.7 73.0 48.3 117.1 69.4 107.8 114.6 76.8 33.3 104.5 41.0 76.0 117.0 116.2 144.0 62.7 134.3 102.0 107.6 176.6 80.2 78.4 35.0 139.6 76.7 37.0 34.0 60.3 125.6 56.1 79.3 97.9 129.5 103.8 89.2 71.2 127.9 39.2 114.7 78.8 73.0 131.2 210.0 98.3 34.7 63.3 96.8 83.9 149.8 56.9 57.3 88.9 103.9 39.1 64.0 106.2 92.9 180.8 176.2 59.2 137.3 158.6 66.5 64.9 105.9 4.6 4.2 4.6 6.1 6.2 5.9 6.5 4.5 6.9 6.1 6.2 5.4 5.8 0.7 8.6 6.2 3.9 5.6 3.1 15.9 19.5 30.8 24.3 21.4 18.0 21.0 17.4 22.9 17.5 20.2 24.6 13.4 25.6 23.6 32.3 17.4 8.5 11.0 17.9 16.5 19.3 11.6 12.3 65.2 12.8 18.8 9.2 37.5 19.4 11.2 13.3 9.8 12.2 119.7 19.7 21.0 16.5 12.1 32.6 61.9 7.8 15.0 27.8 29.0 18.8 37.9 55.5 11.7 8.1 18.7 13.5 63.1 16.9 16.2 17.6 5.6 50.7 19.6 19.6 7.2 30.9 16.5 16.2 16.5 32.6 51.7 13.7 15.2 29.0 26.4 14.2 9.1 9.3 30.7 25.6 19.7 18.0 21.4 107.4 59.3 24.3 11.6 11.5 16.1 83.3 19.8 9.7 CKMT2 SMTCK ENSG00000131730 "Creatine kinase, mitochondrial 2" P17540 5 81233320-81266398 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 49 "heart muscle: 1240.1;skeletal muscle: 1430.8;tongue: 2324.4" "Cell type enriched" "Detected in many" 20 "Cardiomyocytes: 814.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.1" "Cell line enhanced" "Detected in many" "BEWO: 3.5;T-47d: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051880 Enhanced NA NA 3000000 "Cluster 48: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA051880: AB_2681650" "unprognostic (3.64e-3)" "unprognostic (1.15e-1)" "unprognostic (2.82e-3)" "unprognostic (1.88e-2)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (3.57e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.75e-3)" 18.2 33.6 12.3 0.8 15.0 0.1 4.6 17.3 12.3 8.1 24.4 3.2 1.1 6.4 11.4 20.2 6.9 8.1 1240.1 11.2 15.0 14.7 1.0 2.5 1.3 16.3 16.8 10.2 7.7 15.7 4.5 0.7 14.9 13.1 0.7 1.6 26.3 13.1 1430.8 4.7 2.8 8.8 12.0 1.8 17.9 3.6 16.1 0.8 4.9 2324.4 0.4 4.1 4.1 17.7 0.3 0.7 0.8 1.3 1.9 0.4 3.5 0.1 0.0 0.0 0.0 2.4 0.2 1.4 0.4 0.0 1.0 0.0 0.0 0.0 0.0 1.5 2.4 0.1 1.0 3.2 2.6 0.6 0.2 0.8 0.0 0.0 0.0 0.3 0.0 2.1 0.3 0.5 0.0 2.2 1.2 0.2 1.0 0.0 0.7 0.6 1.0 0.1 0.0 0.0 1.4 1.0 1.2 0.3 1.4 1.5 6.3 0.3 0.7 0.4 1.2 0.7 0.2 0.2 0.1 1.3 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 12.3 15.0 17.3 12.3 11.2 15.0 16.3 16.8 14.9 12.0 16.1 17.7 1.8 0.0 0.5 40.1 0.0 0.1 0.4 0.0 1.2 0.9 0.9 0.8 814.1 7.2 0.6 12.9 0.0 0.1 0.0 0.1 37.2 1.7 25.1 13.6 3.5 9.8 0.0 0.0 11.4 0.6 0.4 16.2 6.6 27.8 0.0 0.8 0.0 0.0 0.1 0.0 18.1 0.3 0.0 0.0 0.0 2.2 7.2 0.3 3.6 23.4 0.0 1.4 0.0 4.5 9.1 0.4 0.0 15.1 0.0 0.3 0.3 0.6 0.7 1.0 0.0 11.6 15.0 1.0 0.4 0.1 0.1 0.3 0.8 23.7 2.5 0.2 CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 117.5;skin 1: 88.7;vagina: 53.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 47.4;Basal respiratory cells: 57.5;Basal squamous epithelial cells: 39.9;Club cells: 37.1;Early spermatids: 30.2;Squamous epithelial cells: 167.1;Suprabasal keratinocytes: 54.8;Urothelial cells: 52.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 146.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "hTCEpi: 210.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 96000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: AB_2679977" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-3)" "unprognostic (6.99e-2)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (9.99e-3)" "unprognostic (1.97e-8)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" 0.8 0.1 0.2 0.1 0.6 0.0 4.6 0.4 0.5 22.8 0.1 0.6 0.2 0.0 0.5 117.5 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.7 0.4 2.4 0.7 0.0 13.2 0.2 0.2 88.7 0.8 0.0 0.4 0.0 0.1 0.6 0.3 1.0 0.0 0.0 26.0 21.2 53.1 1.0 0.0 0.0 0.0 0.0 0.6 3.0 38.9 1.7 2.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 0.0 33.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 210.8 1.0 10.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.9 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.4 0.5 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.7 0.0 47.4 13.1 57.5 39.9 0.0 7.7 2.8 0.4 0.0 37.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 5.3 4.1 0.0 3.1 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 2.5 2.1 0.3 0.0 8.0 0.0 0.0 0.0 0.6 0.2 0.0 167.1 54.8 0.1 0.5 0.0 0.1 52.9 CLDN1 "ILVASC, SEMP1" ENSG00000163347 "Claudin 1" O95832 3 190305707-190322446 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 309.8;skin 1: 288.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 440.1;Basal prostatic cells: 291.1;Prostatic glandular cells: 501.6;Squamous epithelial cells: 298.2;Suprabasal keratinocytes: 836.1;Urothelial cells: 562.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "EFO-21: 658.6;HaCaT: 236.5;hTCEpi: 288.6;RPTEC TERT1: 414.9;RT4: 267.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 12 "spinal cord: 25.4" "CAB002602, HPA048319" Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "CAB002602: , HPA048319: AB_2680355" "unprognostic (5.89e-2)" "unprognostic (4.58e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (7.92e-3)" "unprognostic (2.43e-1)" "unprognostic (3.54e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (5.23e-4)" "unprognostic (3.06e-1)" "unprognostic (1.13e-1)" "unprognostic (4.43e-2)" "unprognostic (9.20e-2)" "unprognostic (1.09e-3)" "unprognostic (1.22e-1)" 40.8 47.9 1.5 1.2 1.1 0.2 22.7 0.8 1.3 17.7 20.7 1.7 1.1 64.2 31.9 40.9 56.6 15.5 2.5 1.5 1.2 10.5 309.8 9.1 0.5 1.2 2.8 6.3 34.3 0.4 2.4 5.3 1.7 13.6 1.6 0.9 34.0 46.0 1.1 288.2 0.7 126.6 0.7 1.5 1.0 4.3 1.1 9.4 36.2 4.9 44.2 40.4 35.9 1.0 34.0 29.7 0.2 0.1 0.0 0.1 0.0 2.5 52.7 1.1 2.1 17.7 69.1 0.0 658.6 0.3 58.5 236.5 1.5 77.7 6.2 0.9 1.4 0.1 9.3 41.5 49.6 0.4 0.2 0.5 288.6 6.0 87.0 2.4 0.6 0.0 0.1 0.1 0.1 6.5 0.1 0.1 1.5 2.3 5.5 0.0 0.6 0.2 414.9 267.0 0.2 0.0 31.0 5.7 18.4 3.5 53.5 0.5 12.9 0.6 9.9 0.2 1.4 0.7 0.6 1.2 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.8 1.3 1.5 1.2 1.2 2.8 1.7 0.7 1.1 1.0 0.4 12.8 34.7 0.0 0.5 440.1 291.1 217.3 84.2 0.0 35.6 2.0 1.0 170.1 143.2 31.3 0.0 2.4 0.6 0.6 0.0 203.3 0.1 44.4 10.0 7.0 1.8 0.0 0.7 56.3 0.3 29.2 2.0 100.0 1.3 0.4 1.4 188.2 1.0 0.0 1.6 0.3 54.9 3.8 66.5 1.7 15.5 8.5 32.0 0.0 5.7 0.0 0.0 24.6 0.0 139.9 0.0 35.3 0.0 501.6 0.1 4.1 144.6 0.0 0.0 0.3 11.2 0.3 0.8 298.2 836.1 33.8 2.6 5.0 1.0 562.9 CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 305.0;urinary bladder: 303.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 3149.1;Glandular and luminal cells: 2298.8;Paneth cells: 2081.0;Prostatic glandular cells: 2184.8;Urothelial cells: 8033.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 358.1;BEWO: 395.0;CAPAN-2: 761.4;MCF7: 400.2;OE19: 402.0;PC-3: 495.0;RT4: 340.2;SK-BR-3: 636.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" 2.6 0.4 0.1 23.0 0.0 0.2 69.0 0.8 0.3 61.2 4.8 256.3 126.9 26.7 24.4 305.0 75.8 48.9 0.4 0.2 0.0 116.2 4.8 64.0 1.0 0.4 1.5 1.2 116.2 51.9 13.1 36.3 0.3 82.2 123.3 0.3 204.6 39.1 0.5 180.8 190.6 7.3 0.0 0.7 13.3 0.6 0.2 10.7 111.7 0.3 37.5 303.5 105.7 0.0 358.1 4.4 0.0 1.5 0.0 0.4 395.0 3.3 0.2 0.3 0.4 184.9 761.4 0.6 28.0 0.1 2.6 193.3 0.0 0.5 0.4 0.7 0.4 0.2 20.3 127.0 0.1 0.1 0.9 0.0 1.9 0.1 0.4 0.3 0.0 0.2 0.3 0.7 0.0 400.2 0.7 1.9 0.7 402.0 495.0 0.5 6.9 7.6 92.4 340.2 79.5 1.7 0.4 636.8 0.8 21.6 250.9 0.9 0.5 0.9 13.7 3.1 3.5 0.9 0.7 0.7 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.3 0.2 0.0 0.4 1.5 0.3 0.0 0.2 0.0 5.1 275.7 230.2 0.0 12.2 16.2 3149.1 641.6 31.3 0.4 1255.2 548.4 0.8 287.4 954.3 218.8 0.0 771.7 18.7 1985.0 13.7 1026.1 0.0 1201.7 231.0 41.3 675.5 0.0 0.2 447.1 739.7 27.0 94.8 2298.8 27.3 0.2 0.4 0.5 76.3 0.0 0.1 1266.9 905.3 0.6 8.6 0.0 2.5 29.3 14.2 0.0 15.6 0.8 0.0 0.0 0.0 950.2 2081.0 0.0 2.5 2184.8 1906.1 21.6 635.6 0.0 0.0 0.1 68.2 0.0 0.2 1068.1 54.0 956.1 40.7 0.1 965.1 8033.4 CLDN8 ENSG00000156284 "Claudin 8" P56748 21 30214006-30216097 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 68.9;intestine: 50.8;kidney: 69.3;salivary gland: 40.1" "Group enriched" "Detected in some" 5 "Collecting duct cells: 224.3;Distal enterocytes: 110.2" "Cancer enhanced" "Detected in many" "prostate cancer: 31.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "HaCaT: 33.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA060605 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA060605: AB_2684331" "unprognostic (3.74e-2)" "unprognostic (3.12e-2)" "unprognostic (1.33e-1)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (1.62e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 68.9 0.0 0.0 1.7 0.0 27.2 0.0 0.1 9.3 3.9 1.1 0.0 0.0 0.0 0.0 69.3 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.5 0.0 7.5 50.8 0.0 40.1 13.9 0.0 8.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 21.9 0.0 0.3 0.4 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 10.8 2.7 0.0 0.0 29.9 11.6 0.0 0.0 10.5 224.3 0.0 0.0 0.1 110.2 11.7 0.1 0.0 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.4 0.0 0.3 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 15.9 0.6 0.4 20.3 0.0 0.0 0.0 0.3 0.0 0.0 4.6 8.4 0.0 0.4 0.0 18.0 23.1 CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 41.3" "Group enriched" "Detected in some" 6 "Hofbauer cells: 18.0;Langerhans cells: 67.5;Macrophages: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Group enriched" "Detected in some" 23 "HL-60: 40.9;U-937: 157.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" 1.1 1.8 1.1 7.3 1.2 41.3 0.6 1.3 2.6 0.7 2.1 0.2 0.1 0.3 0.0 1.2 0.5 1.8 0.5 1.0 3.3 0.5 1.8 4.0 0.1 2.2 3.3 0.3 1.3 1.2 0.5 0.9 2.2 0.4 0.3 1.0 1.2 0.5 0.0 2.6 0.0 1.3 1.6 1.1 0.2 0.5 4.9 0.6 0.7 0.0 0.1 2.3 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.3 0.0 0.0 9.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 1.8 1.1 1.2 1.3 2.6 1.0 3.3 2.2 3.3 2.2 1.6 4.9 2.4 0.1 0.0 4.8 0.7 0.6 1.9 0.0 0.0 0.0 0.2 0.1 0.1 0.3 1.5 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.5 0.0 0.0 0.1 0.0 0.2 0.8 0.0 0.0 2.5 0.0 0.0 0.0 18.0 0.0 0.2 0.0 0.0 4.7 67.5 0.7 0.0 58.1 1.8 7.5 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.9 0.4 0.0 0.0 0.2 0.0 0.1 0.0 1.4 0.3 0.4 0.0 0.0 0.0 CLEC7A "CD369, CLECSF12, dectin-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 84.0;lung: 30.9;lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.2;Kupffer cells: 415.2;Langerhans cells: 291.5;Macrophages: 255.5;monocytes: 186.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 249.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Karpas-707: 192.2;U-266/84: 168.1" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" 9.9 5.9 2.2 44.5 2.0 84.0 4.5 2.6 3.7 3.5 3.3 7.5 5.6 3.2 3.7 9.7 5.8 11.1 5.7 1.9 3.3 3.5 11.0 30.9 14.4 5.0 2.7 2.4 2.9 2.0 2.7 7.3 4.0 3.3 7.3 1.7 7.3 3.2 1.3 3.8 8.6 8.7 3.6 34.2 4.6 1.5 3.8 10.0 2.6 2.0 11.9 9.1 4.8 6.1 0.3 0.4 0.1 0.2 0.0 0.0 1.1 0.0 0.5 0.2 0.1 0.1 0.4 0.1 0.1 0.0 1.1 0.6 0.0 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.9 0.7 0.1 0.8 0.1 0.0 0.2 0.1 0.2 0.0 192.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 4.3 0.0 5.2 0.3 0.2 0.3 0.6 0.0 1.4 0.4 0.1 0.3 0.1 0.2 0.2 0.2 11.4 168.1 0.1 0.3 1.0 0.2 1.4 122.9 2.2 0.3 137.2 0.5 0.3 0.3 0.2 60.6 0.3 0.3 0.2 249.6 0.4 148.1 1.0 0.4 40.4 2.2 2.0 2.6 3.7 1.9 3.3 5.0 2.7 4.0 3.6 3.8 6.1 2.0 12.8 15.1 0.3 5.9 3.7 0.2 0.9 8.6 0.0 3.1 2.8 0.9 0.0 9.7 0.0 0.0 1.5 2.1 0.2 0.0 0.1 1.7 0.2 0.1 9.3 0.0 0.0 0.1 0.0 14.1 2.4 0.0 0.1 6.3 0.0 6.1 2.1 87.2 0.0 0.1 0.0 4.1 415.2 291.5 2.2 0.3 255.5 3.6 27.2 186.1 0.0 8.2 0.0 0.0 0.0 1.1 0.0 1.1 0.1 0.0 1.3 2.4 0.4 13.1 1.1 1.0 0.1 0.5 13.2 3.0 5.3 4.1 0.0 0.0 0.5 CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Alveolar cells type 1: 89.8;Alveolar cells type 2: 54.9;Endothelial cells: 60.4;Erythroid cells: 70.7;Kupffer cells: 73.5;Langerhans cells: 135.0;monocytes: 71.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Group enriched" "Detected in some" 5 "HDLM-2: 103.3;K-562: 60.4;Karpas-707: 53.4;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" 23.1 7.1 6.9 16.7 7.8 9.8 16.7 6.9 18.1 20.1 7.6 10.9 8.7 22.6 7.8 9.4 12.5 19.0 14.6 7.1 7.0 5.8 12.8 30.6 30.2 7.7 6.9 21.6 3.5 4.6 4.5 9.3 7.4 4.6 13.6 2.4 6.2 6.3 4.4 6.1 10.3 17.7 7.7 50.1 8.5 3.2 8.5 14.5 31.8 14.3 25.6 15.9 10.7 7.8 0.7 0.0 1.0 0.9 1.0 4.7 0.0 0.2 2.8 0.0 0.4 0.0 0.2 0.1 0.4 0.0 0.2 0.1 0.3 0.0 0.0 103.3 0.5 16.4 0.3 0.0 0.0 0.4 0.6 1.4 0.0 0.0 0.1 0.5 0.1 0.5 60.4 53.4 0.3 0.2 0.1 1.3 0.2 0.1 0.4 0.4 0.0 92.2 0.2 0.2 0.7 0.9 0.0 0.1 0.4 0.2 0.0 1.0 0.0 5.3 1.6 2.0 0.9 3.3 4.6 0.0 2.7 2.6 1.7 0.0 3.5 0.2 0.0 18.6 0.3 0.0 0.1 0.1 47.9 0.0 0.0 0.0 1.4 2.0 14.2 5.2 0.0 2.1 6.9 7.8 6.9 18.1 7.1 7.0 7.7 6.9 7.4 7.7 8.5 7.8 51.2 89.8 54.9 3.9 1.1 13.3 0.8 0.2 2.2 1.2 0.7 1.3 3.2 0.0 5.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.5 11.3 60.4 1.2 70.7 8.6 0.2 0.1 25.6 0.5 0.4 3.8 0.5 27.1 1.2 4.7 0.0 7.0 0.6 0.0 73.5 135.0 1.1 13.7 34.5 17.8 8.4 71.4 0.2 0.0 3.0 2.4 0.1 0.0 9.4 2.0 0.5 0.0 0.6 1.5 0.3 6.6 2.5 4.6 0.3 0.3 0.4 13.8 0.0 2.6 5.2 0.1 1.9 CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 346.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.4;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome" NA NA 5800000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Centrosome" "HPA008019: AB_1846946, HPA060804: AB_2684370" "unprognostic (7.35e-3)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.54e-2)" "unprognostic (7.60e-2)" "unprognostic (2.92e-2)" "unprognostic (9.48e-2)" "unprognostic (6.78e-3)" "unprognostic (1.63e-2)" "unprognostic (5.50e-2)" "unprognostic (4.03e-3)" "unprognostic (1.98e-2)" "unprognostic (7.01e-2)" "prognostic favorable (1.48e-5)" "unprognostic (2.75e-3)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (3.82e-3)" 154.0 58.6 51.8 97.7 70.2 32.3 88.1 61.8 82.7 165.4 39.4 136.3 32.4 201.5 84.6 119.3 103.0 106.5 197.2 50.8 66.5 256.8 72.3 114.6 51.0 73.6 68.0 46.0 49.7 29.3 14.1 120.6 67.0 112.8 66.8 53.1 49.4 152.8 30.7 33.6 54.2 280.4 62.4 43.1 80.0 34.2 88.9 59.6 47.6 53.2 56.4 156.1 73.4 91.4 219.3 25.3 222.7 176.8 299.1 645.6 116.7 561.0 571.4 253.9 304.2 48.3 114.1 129.8 320.1 799.2 77.0 76.8 155.0 151.5 635.7 33.3 64.9 50.0 60.8 88.3 417.3 17.5 6.3 299.3 256.8 363.0 365.1 417.3 427.0 76.0 40.4 138.2 739.0 38.4 34.8 28.5 212.6 50.4 101.8 83.5 247.3 51.5 260.0 58.4 38.9 101.3 144.7 68.4 453.7 228.3 60.0 116.1 601.0 452.2 168.8 199.4 230.1 75.4 111.7 108.6 333.8 151.1 140.5 0.8 5.4 2.5 0.4 4.4 0.0 13.4 0.3 0.2 5.6 11.9 0.1 0.2 1.2 0.0 4.0 1.7 0.0 3.5 51.8 70.2 61.8 82.7 50.8 66.5 73.6 68.0 67.0 62.4 88.9 91.4 178.7 16.0 30.5 24.8 50.8 61.6 50.4 79.8 37.0 3.7 49.9 33.0 172.5 21.5 35.2 14.7 10.4 71.5 2.2 18.1 41.1 39.2 44.9 20.9 103.0 177.1 9.6 40.8 1.5 43.1 211.4 120.5 21.4 53.6 40.0 10.2 88.5 34.4 39.3 1.7 4.2 22.6 20.3 28.2 100.2 27.3 28.6 52.6 129.9 75.9 50.8 13.0 4.1 41.7 196.9 54.7 10.6 87.6 171.2 114.5 0.1 346.1 16.7 26.5 46.0 87.9 162.5 44.0 29.1 29.3 52.0 177.0 8.1 46.5 2.6 49.1 CLN8 "C8orf61, EPMR, FLJ39417, TLCD6" ENSG00000182372 "CLN8 transmembrane ER and ERGIC protein" Q9UBY8 8 1755778-1801711 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 136.8;Syncytiotrophoblasts: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 76.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 76.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "unprognostic (5.86e-2)" "unprognostic (1.95e-2)" "unprognostic (6.40e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (4.05e-3)" "unprognostic (1.21e-1)" "unprognostic (3.45e-1)" "unprognostic (3.03e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-3)" "unprognostic (1.83e-1)" "prognostic favorable (4.36e-8)" "unprognostic (1.36e-1)" "unprognostic (1.70e-1)" "unprognostic (6.24e-2)" "unprognostic (8.38e-2)" 5.4 5.2 11.4 3.7 15.7 9.1 4.3 14.6 12.4 4.7 6.6 4.9 5.0 3.2 11.2 9.8 3.3 7.5 6.2 10.6 11.3 6.2 8.9 8.9 6.5 18.2 15.2 2.5 10.1 8.0 3.5 6.0 18.5 3.8 4.4 3.8 5.1 3.6 5.9 13.2 6.3 4.0 16.9 7.9 6.8 5.9 15.1 3.2 5.1 3.3 7.2 4.4 5.8 24.3 3.6 8.5 6.2 6.5 8.3 8.4 14.8 8.3 5.1 4.2 5.2 8.6 10.0 4.4 2.3 8.2 5.6 13.7 4.9 15.6 8.6 3.3 3.6 4.4 3.2 4.9 4.7 3.7 19.1 8.4 12.2 5.8 4.1 10.1 9.2 3.2 6.0 2.6 13.1 9.0 6.0 3.2 6.1 14.0 7.3 4.2 4.3 3.4 7.8 15.4 3.2 3.9 3.5 8.1 4.6 12.7 16.2 4.2 17.3 11.3 3.2 0.9 5.2 1.5 5.4 5.0 11.4 7.3 16.9 7.4 10.6 4.7 6.4 13.6 7.1 10.3 6.9 4.5 10.6 14.0 6.7 4.4 3.7 5.1 12.5 76.7 8.0 6.4 11.4 15.7 14.6 12.4 10.6 11.3 18.2 15.2 18.5 16.9 15.1 24.3 18.3 9.6 17.5 6.2 30.1 54.7 71.6 38.6 26.7 27.6 23.4 13.2 7.7 20.0 37.2 31.3 31.3 38.0 115.3 28.5 15.6 27.2 5.4 20.5 6.9 34.7 19.7 40.8 7.4 19.0 18.0 32.7 13.7 37.2 27.3 17.1 27.8 28.5 44.1 40.4 7.6 17.5 50.8 54.6 136.8 5.9 8.1 69.8 21.4 8.4 22.3 13.9 23.7 10.1 27.1 19.3 20.7 12.0 9.1 76.5 19.5 10.6 27.1 26.1 13.1 22.5 16.8 34.4 23.5 20.1 63.5 131.6 22.0 16.1 15.4 61.2 CLVS2 "bA160A10.4, C6orf212, C6orf213, RLBP1L2" ENSG00000146352 "Clavesin 2" Q5SYC1 6 122996235-123072925 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 41.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 137.8;Inhibitory neurons: 171.5;Muller glia cells: 60.8" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Region enriched" "Detected in many" 4 "cerebellum: 41.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HEL: 12.2;SCLC-21H: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043764 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043764: AB_10960281" "unprognostic (1.35e-1)" "unprognostic (3.28e-2)" "unprognostic (4.68e-2)" "unprognostic (3.60e-1)" "unprognostic (2.38e-1)" "unprognostic (7.04e-2)" "unprognostic (1.43e-2)" "unprognostic (5.72e-3)" "unprognostic (9.60e-2)" "unprognostic (8.71e-2)" 0.0 0.9 5.8 0.0 5.7 0.0 0.0 41.1 9.2 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 5.8 8.5 0.0 0.0 0.0 0.0 5.3 0.3 0.0 0.0 0.0 1.9 0.0 5.2 3.0 0.1 8.2 0.0 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 0.2 1.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.7 41.1 9.2 5.8 8.5 5.3 0.3 5.2 0.0 0.2 1.9 0.4 0.0 0.0 22.2 0.0 0.0 17.9 0.0 0.0 5.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.9 0.0 0.0 0.3 0.0 0.0 137.8 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 171.5 0.0 0.0 0.0 0.0 0.7 0.3 0.2 0.0 2.8 0.0 60.8 0.0 27.2 4.0 0.0 0.0 0.4 0.0 4.6 0.0 0.0 0.0 4.8 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.6 CMTM5 "CKLFSF5, FLJ37521" ENSG00000166091 "CKLF like MARVEL transmembrane domain containing 5" Q96DZ9 14 23376773-23379772 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 182.4;choroid plexus: 49.5" "Cell type enhanced" "Detected in some" "Macrophages: 93.7;Muller glia cells: 32.0;Oligodendrocyte precursor cells: 20.6;Oligodendrocytes: 106.2" "Group enriched" "Detected in some" 37 "glioma: 8.4;melanoma: 3.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 20.8" "Lineage enriched" "Detected in many" 19 "granulocytes: 20.8" "Cell line enriched" "Detected in some" 7 "HEL: 91.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052338 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 540000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Vesicles" "HPA052338: AB_2681793" "unprognostic (2.73e-3)" "unprognostic (1.51e-1)" "unprognostic (5.24e-1)" "unprognostic (2.43e-3)" "unprognostic (2.63e-1)" "unprognostic (6.40e-2)" "unprognostic (8.34e-3)" "unprognostic (1.78e-1)" "unprognostic (2.27e-2)" "unprognostic (8.40e-2)" "unprognostic (6.24e-4)" "unprognostic (3.03e-3)" "unprognostic (1.97e-3)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.11e-2)" 1.1 1.0 75.6 0.5 119.1 8.2 0.9 123.8 101.7 2.8 49.5 5.8 0.5 0.8 1.1 1.2 1.2 2.1 22.7 73.9 85.2 0.5 0.3 1.5 0.2 150.9 106.2 0.8 0.2 0.1 0.6 0.7 135.2 2.1 0.8 2.3 2.2 3.2 3.1 0.7 1.7 0.8 113.4 2.8 1.4 0.1 110.2 0.1 0.5 0.9 0.0 1.2 2.6 182.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 91.8 0.0 0.0 0.2 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.2 20.8 0.7 0.9 0.1 0.4 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 4.2 0.0 0.0 1.0 0.4 30.0 75.6 119.1 123.8 101.7 73.9 85.2 150.9 106.2 135.2 113.4 110.2 182.4 0.5 0.0 0.0 6.5 0.4 1.0 0.1 0.0 1.2 0.2 1.3 5.5 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.4 0.0 0.0 93.7 5.4 0.0 1.5 32.0 0.0 20.6 106.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.6 3.4 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.1 CNFN PLAC8L2 ENSG00000105427 Cornifelin Q9BYD5 19 42387019-42390297 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 952.0;esophagus: 3093.3;vagina: 1442.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 57.9;Breast myoepithelial cells: 51.6;Squamous epithelial cells: 71.8" "Cancer enhanced" "Detected in all" "head and neck cancer: 367.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "memory B-cell: 61.2;naive B-cell: 70.2" "Lineage enriched" "Detected in many" 12 "B-cells: 70.2" "Cell line enhanced" "Detected in many" "A549: 18.1;HEK 293: 25.7;MCF7: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA049073, HPA053997" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge" "HPA049073: AB_2680620, HPA053997: AB_2682337" "unprognostic (5.08e-2)" "unprognostic (4.21e-3)" "unprognostic (2.52e-1)" "unprognostic (7.22e-2)" "unprognostic (3.15e-2)" "unprognostic (8.35e-3)" "unprognostic (6.04e-2)" "unprognostic (2.06e-3)" "unprognostic (3.52e-1)" "unprognostic (9.44e-2)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (8.42e-2)" "unprognostic (4.83e-2)" "unprognostic (7.77e-3)" "prognostic favorable (4.02e-5)" "unprognostic (2.45e-1)" 4.3 5.3 1.8 0.4 4.2 0.6 12.9 1.9 2.2 952.0 1.3 3.2 0.4 1.5 7.3 3093.3 1.6 0.1 1.9 1.9 2.8 2.3 1.4 0.9 0.7 2.1 1.9 1.0 3.3 1.6 2.2 0.1 1.7 8.6 1.3 0.1 661.6 1.1 1.7 555.6 3.5 0.5 1.7 3.3 3.3 2.4 2.9 2.8 1.8 0.0 276.8 2.4 1442.7 1.6 6.0 18.1 0.4 1.6 0.8 0.9 0.2 1.0 0.3 0.4 0.4 1.0 1.6 5.1 8.0 0.2 1.2 2.4 1.5 2.3 0.1 0.0 25.7 0.4 6.9 1.9 0.0 0.0 0.1 1.8 4.0 1.0 0.0 0.1 0.0 4.7 1.1 0.2 0.0 12.6 0.1 0.1 6.6 8.1 5.4 2.2 0.3 2.9 1.6 2.3 2.7 7.7 3.4 5.1 2.5 2.7 6.2 2.6 0.0 0.0 5.3 0.2 0.1 5.8 7.6 3.6 0.1 2.2 0.3 0.1 4.6 0.1 1.7 3.9 0.4 61.2 1.3 1.2 5.9 70.2 0.6 0.9 1.3 0.0 0.9 1.3 0.1 2.2 1.8 4.2 1.9 2.2 1.9 2.8 2.1 1.9 1.7 1.7 2.9 1.6 32.7 3.2 2.2 0.0 24.6 4.6 16.8 28.5 14.8 0.1 57.9 51.6 0.8 2.8 20.2 33.1 0.0 0.2 2.1 24.5 7.9 13.1 1.5 20.6 3.9 9.3 32.5 3.6 0.1 2.5 0.3 2.3 4.6 23.9 4.5 7.2 3.9 0.7 5.7 0.0 0.2 33.4 14.2 3.8 7.7 3.9 5.3 6.3 3.6 0.0 6.4 0.3 7.2 0.0 0.1 2.4 39.4 4.5 0.5 11.5 43.8 12.3 10.5 0.1 0.0 0.9 8.0 0.4 17.4 71.8 12.9 0.3 1.3 1.1 41.8 27.0 CNGB1 "CNCG2, CNCG3L, CNGB1B, GAR1, GARP, RCNC2, RCNCb, RP45" ENSG00000070729 "Cyclic nucleotide gated channel subunit beta 1" Q14028 16 57882340-57971128 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Olfaction, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "retina: 600.2" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 331.5;Rod photoreceptor cells: 1111.1" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.5;RPMI-8226: 1.8;SCLC-21H: 5.0;SiHa: 2.9;SK-BR-3: 1.4" "Region enhanced" "Detected in some" "hypothalamus: 4.5" "HPA039159, HPA060355" Approved Vesicles,Cytosol No NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Vesicles "HPA039159: AB_10795579, HPA060355: " "unprognostic (5.52e-3)" "unprognostic (4.51e-3)" "unprognostic (1.06e-1)" "unprognostic (2.73e-3)" "unprognostic (6.20e-2)" "unprognostic (1.76e-1)" "unprognostic (8.56e-4)" "unprognostic (3.08e-1)" "unprognostic (9.84e-2)" "unprognostic (2.83e-1)" "unprognostic (2.14e-4)" "unprognostic (5.42e-2)" "unprognostic (1.01e-3)" "unprognostic (5.20e-2)" "unprognostic (1.88e-1)" "unprognostic (4.57e-2)" "unprognostic (9.07e-2)" 0.1 2.5 15.5 1.1 13.2 0.2 0.0 0.0 20.4 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.1 0.3 0.0 24.5 24.8 0.0 0.1 0.1 0.2 2.8 3.2 0.0 0.5 0.0 0.2 0.4 4.4 0.0 0.4 600.2 0.0 0.1 0.0 0.2 0.6 0.1 2.4 0.1 0.0 0.4 36.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.5 0.0 0.5 0.0 0.0 1.3 0.0 0.1 0.0 0.3 0.9 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 1.8 0.0 0.6 5.0 0.0 2.9 1.4 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.2 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 15.5 13.2 0.0 20.4 24.5 24.8 2.8 3.2 4.4 2.4 36.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.4 0.0 61.6 0.3 0.0 1.1 0.0 0.1 0.0 331.5 6.9 0.0 0.0 0.0 0.4 1.6 0.9 0.1 4.2 0.0 0.0 3.2 0.4 0.9 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.4 25.2 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 89.5 0.0 1.0 0.1 0.2 1.1 0.0 0.0 0.2 0.0 0.3 0.0 1111.1 0.0 0.1 0.2 0.5 0.7 0.0 0.0 1.4 0.1 0.1 0.0 0.2 CNKSR2 "CNK2, KIAA0902, KSR2" ENSG00000149970 "Connector enhancer of kinase suppressor of Ras 2" Q8WXI2 X 21372801-21654695 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 22.6;retina: 17.9" "Cell type enhanced" "Detected in many" "Astrocytes: 111.7;Excitatory neurons: 497.7;Inhibitory neurons: 143.6;Oligodendrocyte precursor cells: 93.5;Rod photoreceptor cells: 86.1" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.9;AF22: 4.0;NTERA-2: 8.9;PC-3: 4.8;RH-30: 8.2;U-251 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001502 Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 58: Brain - Synaptic function" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" "HPA001502: AB_1078542" "unprognostic (1.33e-2)" "unprognostic (1.00e-3)" "unprognostic (5.35e-2)" "unprognostic (4.90e-4)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (4.35e-3)" "unprognostic (2.58e-2)" "unprognostic (3.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.35e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "unprognostic (2.72e-2)" "unprognostic (3.93e-2)" "unprognostic (2.27e-2)" "unprognostic (4.13e-2)" 1.5 2.6 8.4 0.3 12.2 0.2 1.4 22.6 16.4 1.0 0.0 0.7 0.1 0.3 0.5 0.0 1.3 0.1 0.8 20.3 0.0 0.1 0.7 1.2 0.9 0.0 0.0 0.6 2.5 0.0 1.6 0.1 0.0 0.7 0.0 17.9 0.5 0.1 4.7 0.8 0.6 0.1 0.0 0.5 1.2 0.6 0.0 0.9 0.9 1.3 1.0 0.6 0.9 5.3 0.0 5.9 4.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 2.0 0.0 8.9 0.0 4.8 0.0 8.2 0.0 0.0 0.0 3.9 1.6 0.0 0.1 0.3 2.1 0.0 0.6 0.0 0.1 1.9 0.0 5.3 3.1 0.0 3.4 0.8 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.9 0.8 0.2 0.0 0.0 0.0 0.0 0.2 0.1 8.4 12.2 22.6 16.4 20.3 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.3 16.0 1.3 111.7 9.0 1.3 0.5 0.0 1.2 17.8 0.3 0.6 5.7 1.5 5.6 0.0 20.9 0.1 2.1 0.4 0.0 0.3 0.3 1.0 13.6 0.3 0.0 0.8 497.7 2.3 0.0 6.7 0.0 1.3 1.3 1.0 0.0 2.1 0.1 23.5 143.6 0.5 0.0 0.0 2.6 0.0 0.6 0.2 0.0 15.9 0.2 12.7 0.0 93.5 10.6 0.6 0.1 1.5 3.1 2.0 1.3 0.3 0.0 86.1 0.0 0.6 0.9 6.0 7.7 0.1 1.8 0.0 2.9 1.5 0.4 0.0 CNKSR3 "FLJ31349, MAGI1" ENSG00000153721 "CNKSR family member 3" Q6P9H4 6 154387515-154510685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.6;Glandular and luminal cells: 155.4;Oligodendrocytes: 142.3;Skeletal myocytes: 211.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 21.1" "CAB037133, HPA049651" Approved Supported Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" Cytosol Mitochondria "CAB037133: AB_477217, HPA049651: AB_2680841" "unprognostic (3.07e-1)" "unprognostic (3.25e-2)" "unprognostic (1.57e-1)" "unprognostic (2.34e-1)" "unprognostic (5.62e-2)" "unprognostic (1.25e-2)" "unprognostic (1.37e-1)" "unprognostic (5.78e-2)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-3)" "unprognostic (4.90e-2)" "prognostic favorable (6.00e-4)" "unprognostic (4.23e-2)" "unprognostic (8.79e-2)" "unprognostic (1.57e-3)" "unprognostic (3.38e-1)" 3.7 1.1 6.4 1.9 7.6 0.9 3.2 4.8 5.5 4.0 15.0 6.5 5.8 7.6 1.9 13.3 4.1 4.9 6.4 3.6 4.2 7.7 9.7 3.7 1.4 7.8 8.3 6.1 18.9 0.7 2.3 5.6 7.2 3.3 3.4 2.6 5.7 4.8 1.1 3.9 6.4 6.6 5.3 4.5 4.0 4.4 12.7 2.1 2.1 1.4 2.5 4.3 5.3 13.3 0.4 4.9 3.3 6.8 5.8 4.1 0.4 6.0 3.5 10.2 8.3 21.1 0.5 0.1 6.4 6.6 3.4 2.1 9.5 0.7 5.3 0.0 6.3 15.4 1.0 12.1 2.5 0.0 2.7 6.1 3.2 3.9 4.1 1.6 3.2 1.3 2.2 0.1 2.8 1.2 0.1 0.2 2.3 4.1 6.2 4.6 5.9 8.0 11.7 3.1 2.0 12.6 2.8 1.5 1.3 1.4 0.0 1.3 3.7 0.9 3.0 7.7 4.0 0.1 0.0 0.2 0.2 0.3 4.4 0.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.1 0.1 0.2 0.0 0.0 6.4 7.6 4.8 5.5 3.6 4.2 7.8 8.3 7.2 5.3 12.7 13.3 24.7 12.8 38.4 9.4 0.9 26.5 15.4 7.8 12.5 2.0 11.0 8.3 33.8 30.0 20.2 25.8 0.0 9.2 0.4 31.0 9.8 20.3 42.5 109.6 14.7 66.8 43.2 15.6 23.8 12.3 1.1 12.9 9.2 155.4 5.7 10.8 61.8 65.9 1.7 0.0 1.5 18.4 10.2 7.1 22.5 23.6 5.9 3.5 32.0 24.4 0.8 22.8 0.0 54.8 142.3 7.3 18.5 10.5 0.5 18.7 43.6 31.8 11.7 2.5 0.0 211.8 8.0 1.2 6.3 29.4 23.9 21.5 2.6 14.8 14.1 10.0 CNN3 ENSG00000117519 "Calponin 3" Q15417 1 94896949-94927223 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "glioma: 315.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 10.5;naive CD4 T-cell: 11.6" "Group enriched" "Detected in many" 12 "B-cells: 10.5;T-cells: 11.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009849, HPA051237" Enhanced Enhanced "Actin filaments,Cytosol" NA NA 660000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" Cytosol "CAB009849: AB_2276410, HPA051237: AB_2681399" "unprognostic (8.47e-2)" "unprognostic (5.19e-2)" "unprognostic (5.22e-2)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-2)" "unprognostic (8.87e-2)" "unprognostic (5.20e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-3)" "unprognostic (2.33e-2)" "unprognostic (8.71e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.99e-4)" 163.9 255.6 152.7 78.9 153.7 2.1 160.0 148.6 186.3 164.8 147.7 142.4 135.9 214.0 71.0 149.7 147.1 152.3 127.6 151.7 189.9 245.1 143.7 209.0 51.4 197.4 170.9 153.1 83.3 53.1 101.7 256.0 173.1 126.2 82.8 125.0 125.5 133.7 26.3 62.5 100.0 196.0 180.8 94.1 111.8 50.2 164.5 55.1 125.0 52.6 44.3 156.5 166.2 174.0 416.6 77.9 429.0 380.1 286.0 264.2 191.7 197.2 381.3 319.4 511.2 348.7 35.6 0.1 436.6 243.4 315.7 116.2 307.2 169.9 428.1 1.6 113.0 18.8 47.5 256.2 545.0 0.2 0.8 246.2 25.5 394.1 89.4 539.6 282.8 26.7 4.1 35.3 798.9 0.2 19.8 0.9 333.6 0.3 43.3 0.6 524.2 1.8 392.9 156.6 26.3 264.2 163.0 65.0 272.8 301.7 124.8 38.5 182.4 212.2 364.9 80.2 647.0 43.9 27.2 1.5 46.0 0.6 327.1 0.2 0.0 0.0 2.2 0.1 3.4 4.6 2.1 1.2 0.1 10.5 11.6 8.3 0.4 0.9 0.1 0.0 0.0 2.6 152.7 153.7 148.6 186.3 151.7 189.9 197.4 170.9 173.1 180.8 164.5 174.0 183.5 150.6 80.7 82.9 18.1 78.3 435.7 232.3 48.9 11.9 122.2 64.1 42.2 88.6 156.2 126.9 20.9 236.1 3.2 36.0 436.3 275.1 156.1 77.4 151.1 278.3 72.4 20.0 12.9 240.7 40.9 287.8 33.1 104.9 14.0 164.4 373.0 152.1 22.6 1.7 16.9 58.7 429.3 20.1 56.3 150.7 274.6 9.3 197.5 29.0 4.7 394.6 0.0 62.4 22.7 130.8 53.2 382.1 2.6 319.1 117.9 518.5 95.1 14.4 263.0 399.8 374.9 10.8 34.7 91.4 77.7 205.8 14.9 214.5 131.0 327.4 CNNM1 ACDP1 ENSG00000119946 "Cyclin and CBS domain divalent metal cation transport mediator 1" Q9NRU3 10 99329356-99394330 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;testis: 9.8" "Cell type enhanced" "Detected in many" "Early spermatids: 103.1;Excitatory neurons: 69.9;Horizontal cells: 50.5;Inhibitory neurons: 89.5;Late spermatids: 88.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.6;BJ hTERT+: 7.4;BJ hTERT+ SV40 Large T+ RasG12V: 11.3;HAP1: 8.7;OE19: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040408 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA040408: AB_10793963" "unprognostic (9.04e-4)" "unprognostic (2.93e-1)" "unprognostic (1.70e-1)" "unprognostic (7.60e-4)" "unprognostic (4.08e-3)" "unprognostic (9.51e-2)" "unprognostic (6.01e-2)" "unprognostic (2.27e-2)" "unprognostic (6.03e-2)" "unprognostic (1.94e-1)" "unprognostic (3.09e-2)" "unprognostic (2.45e-1)" "unprognostic (8.94e-2)" "unprognostic (1.50e-1)" "unprognostic (4.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.03e-1)" 0.2 1.1 9.9 0.2 9.9 0.0 0.5 5.4 16.7 1.8 0.0 0.7 0.4 0.9 1.7 0.8 1.0 0.3 0.1 7.3 7.3 1.7 0.2 0.1 0.0 3.6 2.9 2.6 1.1 0.6 3.6 0.0 3.5 1.7 0.4 5.2 0.8 0.8 0.0 1.2 0.6 0.4 2.0 0.1 0.6 9.8 4.7 0.1 0.1 0.1 0.1 1.7 1.4 10.1 0.0 19.6 0.0 0.0 0.0 0.0 0.0 2.8 7.4 6.7 11.3 0.0 4.4 0.0 0.0 1.4 0.1 1.7 8.7 0.0 4.8 0.0 0.9 1.9 2.8 3.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.4 2.7 0.3 0.0 0.9 7.7 0.8 0.0 0.0 0.0 0.9 0.0 2.2 6.1 2.0 0.4 1.0 0.5 0.0 0.0 0.0 0.6 0.1 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 9.9 5.4 16.7 7.3 7.3 3.6 2.9 3.5 2.0 4.7 10.1 0.6 0.0 0.0 4.6 0.0 2.3 3.3 0.1 5.2 25.3 0.7 2.8 1.4 0.0 0.2 1.8 14.6 0.0 0.0 0.0 0.0 0.6 103.1 0.5 1.0 0.4 0.0 0.8 69.9 1.5 0.0 1.0 0.0 0.3 0.0 0.2 1.8 0.0 0.0 50.5 89.5 0.1 0.0 0.0 0.8 88.0 2.1 0.3 1.8 4.7 0.1 1.3 0.0 10.6 2.2 2.0 0.3 2.6 0.0 5.9 0.1 0.7 0.6 3.4 0.0 2.0 0.5 1.9 1.6 1.5 1.0 0.0 0.2 1.2 0.1 2.4 CNTLN "bA340N12.1, C9orf101, C9orf39, FLJ20276" ENSG00000044459 Centlein Q9NXG0 9 17134982-17503923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8;Spermatocytes: 84.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Cell line enhanced" "Detected in many" "HEL: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007201, HPA036728, HPA036729" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Centrosome "Nucleoplasm, Cytosol" "HPA007201: AB_2667775, HPA036728: AB_10670847, HPA036729: AB_10670240" "unprognostic (1.97e-2)" "unprognostic (2.81e-3)" "unprognostic (1.81e-1)" "unprognostic (2.48e-1)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (7.71e-2)" "unprognostic (1.68e-1)" "unprognostic (7.71e-3)" "unprognostic (5.07e-3)" "unprognostic (1.06e-1)" "unprognostic (6.65e-2)" "unprognostic (2.47e-1)" "unprognostic (5.38e-2)" "unprognostic (3.35e-2)" "unprognostic (1.37e-1)" "unprognostic (5.80e-2)" 4.4 2.4 2.3 2.1 2.4 7.3 3.5 7.7 2.2 5.0 3.3 4.5 1.2 7.1 2.4 2.7 4.3 4.2 2.3 1.7 2.6 2.4 10.5 2.8 2.7 2.7 3.1 8.8 1.7 4.4 2.2 3.6 3.0 2.7 2.2 2.1 1.6 3.2 1.6 1.9 2.2 4.5 2.6 3.9 1.9 5.2 2.5 2.8 3.1 2.5 1.6 3.5 3.5 2.8 8.3 5.6 12.1 6.8 5.8 13.6 0.4 9.5 6.3 7.0 9.5 0.4 2.7 6.0 1.5 6.6 7.5 0.3 14.1 3.9 10.9 0.3 4.9 35.5 11.7 2.0 6.4 4.9 7.4 8.6 2.0 5.8 5.7 6.5 10.0 2.2 1.3 1.1 11.3 0.6 4.0 7.8 9.4 1.4 10.3 5.8 11.2 3.0 4.1 2.0 7.6 7.9 11.6 0.2 3.0 4.8 2.3 12.3 7.5 9.5 3.7 10.4 8.3 4.7 6.1 0.1 4.4 6.1 4.4 0.2 1.3 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.1 0.5 3.9 0.7 0.1 0.2 2.3 2.4 7.7 2.2 1.7 2.6 2.7 3.1 3.0 2.6 2.5 2.8 32.0 6.4 17.6 59.7 1.6 8.8 13.7 6.1 13.1 12.3 3.6 5.8 13.4 7.2 3.4 9.2 0.0 2.5 1.1 2.4 5.9 10.1 16.3 23.4 30.7 24.9 2.4 17.1 20.3 12.0 5.2 29.2 4.1 17.0 7.6 42.4 20.0 38.8 18.4 20.2 37.2 5.9 4.1 40.3 11.6 8.8 45.7 24.0 8.8 91.8 31.0 21.4 1.0 70.4 29.6 4.0 0.8 30.9 1.8 3.8 5.3 8.5 6.7 8.1 13.1 34.2 21.3 84.3 48.9 5.3 5.5 1.0 1.7 31.6 5.5 6.3 CNTN4 BIG-2 ENSG00000144619 "Contactin 4" Q8IWV2 3 2098813-3057959 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 411.7;Excitatory neurons: 960.7;Inhibitory neurons: 1048.5;Oligodendrocyte precursor cells: 248.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 8.3;CACO-2: 9.0;HEK 293: 5.5;SH-SY5Y: 16.5;WM-115: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 170000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.64e-1)" "unprognostic (7.17e-3)" "unprognostic (9.85e-2)" "unprognostic (5.75e-2)" "unprognostic (9.94e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-1)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (2.60e-2)" "unprognostic (7.38e-3)" "unprognostic (2.41e-2)" "prognostic favorable (1.00e-4)" "unprognostic (1.22e-2)" "unprognostic (2.88e-2)" "unprognostic (2.10e-1)" "unprognostic (2.13e-1)" 3.4 0.5 2.2 1.1 6.4 0.0 2.5 13.5 12.3 8.7 0.0 4.6 1.8 8.3 1.9 3.1 4.2 5.1 2.5 1.8 2.7 4.2 2.9 2.4 1.1 0.5 5.4 1.0 1.6 22.6 1.9 7.9 1.2 4.3 3.3 19.8 0.9 5.6 0.7 0.7 4.1 4.5 4.2 1.0 3.6 13.4 7.7 2.2 10.3 4.0 2.6 3.6 1.7 4.0 0.0 0.0 1.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 16.5 0.0 0.0 0.1 1.2 0.1 0.2 0.0 0.0 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 6.4 13.5 12.3 1.8 2.7 0.5 5.4 1.2 4.2 7.7 4.0 0.4 9.6 3.6 26.8 0.1 0.8 1.3 0.0 1.8 96.5 2.0 1.8 1.4 7.2 5.6 0.0 0.0 0.1 0.0 1.8 0.0 4.4 411.7 0.3 9.1 1.9 7.8 0.0 960.7 0.0 0.1 18.1 0.0 0.3 0.0 6.9 0.7 0.4 0.3 101.0 1048.5 2.0 0.0 0.3 0.7 156.3 5.0 0.4 1.8 31.9 0.0 27.5 0.0 248.3 14.7 0.0 1.6 5.3 0.4 0.4 3.7 3.7 0.0 5.9 6.6 0.5 8.3 4.5 4.9 0.9 0.0 0.3 0.1 0.1 3.5 0.2 CNTNAP2 "Caspr2, KIAA0868, NRXN4" ENSG00000174469 "Contactin associated protein 2" Q9UHC6 7 146116002-148420998 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Autism, Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 20.7;retina: 14.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3383.0;Inhibitory neurons: 6845.7" "Cancer enhanced" "Detected in many" "prostate cancer: 10.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 25 "B-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 8.0;CACO-2: 6.7;NTERA-2: 12.0;SCLC-21H: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002739 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002739: AB_1078545" "unprognostic (2.49e-2)" "unprognostic (1.49e-2)" "unprognostic (4.05e-1)" "unprognostic (3.08e-3)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (2.51e-2)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (3.67e-2)" "unprognostic (2.68e-1)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.00e-3)" 0.2 0.8 10.0 0.2 13.8 0.0 0.6 1.4 20.7 0.1 0.0 0.8 0.0 0.0 0.0 0.4 0.6 0.0 0.2 5.6 5.7 0.1 1.9 0.0 0.4 5.7 0.5 1.1 0.2 0.3 3.8 0.5 3.8 4.1 0.4 14.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.4 0.2 0.5 1.8 3.7 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 8.0 3.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.7 0.1 0.0 0.0 0.2 0.0 2.0 1.7 0.6 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.0 1.4 0.0 0.0 0.0 2.2 0.0 0.0 21.5 1.4 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.0 13.8 1.4 20.7 5.6 5.7 5.7 0.5 3.8 0.0 1.8 0.0 0.1 0.0 0.0 65.6 9.3 0.1 0.3 15.5 1.8 33.9 0.3 0.0 1.2 7.2 4.1 0.0 2.1 40.8 0.0 1.8 0.0 1.4 7.2 0.6 0.0 0.6 2.4 0.0 3383.0 0.7 6.8 1.1 0.5 0.7 0.0 0.2 0.0 8.9 3.3 1031.4 6845.7 3.9 0.0 0.6 2.0 2.7 1.2 0.4 0.0 180.8 0.2 8.2 1.0 429.3 914.7 4.1 2.1 0.0 0.3 7.4 4.7 0.5 0.9 16.7 0.0 0.0 0.9 2.4 12.0 9.1 0.0 6.3 0.0 1.2 6.8 0.2 CNTNAP3 "CASPR3, CNTNAP3A, FLJ14195, KIAA1714" ENSG00000106714 "Contactin associated protein family member 3" Q9BZ76 9 39072767-39288315 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 26.1;Excitatory neurons: 18.6;Hepatic stellate cells: 30.0;Inhibitory neurons: 103.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "neutrophil: 7.3" "Lineage enriched" "Detected in single" 74 "granulocytes: 7.3" "Cell line enhanced" "Detected in many" "A549: 18.9;AF22: 22.5;TIME: 14.5;WM-115: 37.9" HPA047731 Uncertain "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA047731: AB_2680137" "unprognostic (9.06e-3)" "unprognostic (3.07e-2)" "unprognostic (5.74e-2)" "unprognostic (7.89e-2)" "unprognostic (7.03e-2)" "unprognostic (2.33e-3)" "unprognostic (4.58e-2)" "unprognostic (1.34e-2)" "unprognostic (1.51e-1)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (3.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.15e-2)" "unprognostic (1.20e-1)" "unprognostic (1.95e-3)" "unprognostic (1.93e-3)" 2.7 0.4 4.8 0.5 7.6 1.2 3.2 0.4 2.7 1.3 2.7 4.0 0.8 0.6 0.5 7.2 2.2 1.2 4.0 5.0 3.3 1.8 0.8 1.1 0.3 0.9 5.4 0.3 0.4 0.1 1.1 1.6 0.9 1.5 1.3 2.7 3.4 1.4 0.4 7.2 1.8 2.3 0.1 2.6 0.6 1.8 1.7 2.5 1.2 0.7 0.6 1.0 2.5 2.8 1.1 18.9 22.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 0.0 1.4 4.7 1.9 4.4 0.0 0.0 1.6 0.0 5.2 0.5 0.2 0.3 0.0 0.5 4.1 0.0 1.7 9.4 8.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.9 0.2 5.7 0.0 0.6 5.4 0.4 0.8 2.1 0.7 6.7 0.0 3.7 2.4 0.0 3.2 14.5 0.0 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 37.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 4.8 7.6 0.4 2.7 5.0 3.3 0.9 5.4 0.9 0.1 1.7 2.8 8.0 3.2 1.7 26.1 0.0 6.2 4.0 1.8 18.2 1.3 0.9 3.0 3.5 4.3 1.5 1.8 2.1 0.8 0.0 0.1 0.0 0.4 1.9 1.4 0.7 7.5 3.5 0.0 18.6 0.2 2.5 1.2 0.0 0.2 0.0 0.1 30.0 1.3 0.1 0.0 103.1 0.3 0.0 1.6 0.8 0.9 0.3 0.2 0.0 13.1 0.0 10.5 0.0 3.0 13.3 0.7 0.0 0.0 1.2 1.4 0.0 1.9 4.1 0.7 0.0 0.5 0.9 1.7 8.8 10.4 7.7 0.7 0.4 0.0 0.1 2.7 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL15A1 ENSG00000204291 "Collagen type XV alpha 1 chain" P39059 9 98943179-99070792 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 229.2" "Cell type enhanced" "Detected in many" "Adipocytes: 307.0;Endothelial cells: 190.5;Fibroblasts: 202.3;Leydig cells: 326.8;Peritubular cells: 483.3;Theca cells: 333.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 26.4;BJ hTERT+: 55.6;HDLM-2: 24.5;K-562: 18.8;U-2197: 45.6;U-87 MG: 20.6;WM-115: 31.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "spinal cord: 44.3" "HPA017913, HPA017915" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 28000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA017913: AB_1847099, HPA017915: AB_1847100" "unprognostic (4.30e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-2)" "unprognostic (2.09e-1)" "unprognostic (1.09e-2)" "prognostic favorable (5.47e-4)" "unprognostic (3.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-3)" "unprognostic (3.66e-3)" "unprognostic (8.98e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (3.08e-4)" 84.7 36.9 0.6 50.6 0.9 0.1 46.7 0.8 1.0 31.2 4.0 44.5 12.9 53.8 19.2 26.9 17.3 42.8 58.0 0.4 0.8 12.9 1.0 11.1 10.4 0.6 0.9 23.2 26.8 11.8 6.0 229.2 0.7 21.6 16.3 0.0 35.9 14.3 56.5 15.1 17.7 108.9 0.6 3.7 27.3 27.0 2.4 13.0 21.1 34.4 8.6 42.1 15.1 0.7 0.0 0.0 0.1 0.0 4.6 2.6 0.1 26.4 55.6 1.4 0.5 0.0 0.0 0.2 0.7 5.8 0.2 0.1 0.0 0.0 0.2 24.5 0.0 0.3 12.9 0.0 1.1 0.4 2.5 7.6 0.0 6.0 0.2 0.0 0.0 0.0 18.8 0.0 2.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 14.7 0.2 0.0 0.0 0.1 0.1 0.8 3.9 7.4 0.3 0.2 0.6 0.0 0.1 0.6 45.6 0.5 0.2 0.0 0.0 20.6 0.2 31.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.8 1.0 0.4 0.8 0.6 0.9 0.7 0.6 2.4 0.7 307.0 0.0 0.0 0.7 0.5 19.5 0.1 0.0 5.2 0.0 2.6 4.1 8.1 0.0 0.0 0.0 0.0 3.8 1.8 0.0 0.0 2.4 5.7 3.9 103.4 190.5 0.0 0.0 0.4 0.8 3.7 202.3 0.5 2.2 0.0 0.3 0.0 0.0 7.6 0.0 2.9 0.0 0.0 0.3 27.2 22.5 326.8 3.1 17.8 46.9 0.6 0.0 1.0 1.0 0.3 0.6 0.0 483.3 0.3 1.2 0.0 0.5 0.0 0.0 13.1 107.8 52.8 1.9 1.2 1.3 16.3 7.7 2.1 333.4 0.0 0.7 COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 479.6;Sertoli cells: 223.5;Smooth muscle cells: 268.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 139.0;EFO-21: 309.4;NTERA-2: 170.6;RPTEC TERT1: 131.6;TIME: 186.0" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" 136.4 87.6 14.5 33.9 22.3 15.9 97.1 26.4 21.8 229.4 34.4 91.2 30.4 135.6 35.4 50.1 118.3 28.9 122.2 15.7 18.1 218.2 561.9 83.2 19.8 43.7 28.6 257.3 102.3 7.9 106.5 40.7 39.1 91.0 5.5 5.4 35.8 46.8 26.5 77.8 65.7 28.5 26.6 86.8 44.5 30.0 27.0 9.0 101.1 7.4 7.2 109.8 112.2 45.4 10.5 84.0 20.6 18.0 38.6 31.9 3.3 82.0 139.0 39.1 10.5 48.8 28.9 1.5 309.4 82.8 21.6 37.9 4.6 5.0 7.4 0.7 20.0 47.9 1.4 69.6 37.3 0.7 4.4 37.6 3.3 3.8 4.5 8.5 121.3 0.5 49.6 0.3 14.4 16.7 0.8 3.2 170.6 3.2 30.7 0.7 12.6 4.0 131.6 1.3 22.8 16.3 7.6 7.8 26.6 73.0 7.5 9.9 186.0 0.5 11.4 0.4 17.7 0.4 0.8 1.5 0.1 1.7 32.7 0.8 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.2 3.2 0.0 0.0 0.1 0.0 0.1 14.5 22.3 26.4 21.8 15.7 18.1 43.7 28.6 39.1 26.6 27.0 45.4 156.9 0.0 4.1 6.5 3.9 67.7 15.5 19.0 67.7 13.5 9.3 32.1 15.7 61.5 5.0 112.2 4.2 1.9 3.4 0.1 9.8 117.5 1.5 58.3 99.5 91.2 0.0 33.0 4.9 5.8 1.1 101.1 3.6 144.2 57.8 6.6 75.0 479.6 2.4 0.0 15.8 0.1 4.1 12.1 32.5 6.7 79.9 6.5 49.8 82.4 3.2 141.9 7.2 4.0 28.0 9.9 0.0 126.0 4.6 14.0 0.0 72.9 0.7 6.3 223.5 138.2 268.6 4.1 6.0 7.9 28.6 2.5 15.3 47.5 0.4 2.6 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 COL6A6 ENSG00000206384 "Collagen type VI alpha 6 chain" A6NMZ7 3 130560334-130678155 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "parathyroid gland: 97.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.6;Fibroblasts: 20.6;Inhibitory neurons: 5.3;Oligodendrocytes: 4.6;Skeletal myocytes: 3.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SuSa: 1.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "spinal cord: 10.0" HPA045239 Uncertain "Secreted to extracellular matrix" NA NA 700000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA045239: AB_2679268" "unprognostic (4.86e-3)" "unprognostic (2.16e-2)" "unprognostic (9.91e-2)" "unprognostic (2.08e-4)" "unprognostic (2.79e-1)" "unprognostic (1.11e-5)" "unprognostic (3.74e-3)" "unprognostic (5.59e-2)" "unprognostic (1.42e-1)" "unprognostic (3.50e-2)" "unprognostic (8.90e-2)" "unprognostic (2.70e-1)" "unprognostic (2.96e-4)" "unprognostic (5.82e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (1.07e-1)" 1.8 0.0 0.0 0.0 0.2 0.2 2.5 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.3 0.9 0.3 0.1 3.3 0.0 0.0 0.0 0.8 7.3 0.0 0.0 0.0 0.2 0.0 97.8 3.6 0.7 0.0 0.0 0.0 0.3 1.5 0.0 0.1 0.4 0.0 0.5 0.0 1.2 0.1 0.4 0.1 1.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 1.1 1.3 0.0 0.9 0.0 0.0 0.0 1.1 0.2 0.4 2.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 2.9 0.1 0.0 0.0 4.6 0.0 0.0 20.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.3 0.0 0.0 0.0 1.5 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 3.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 3.3 0.8 0.0 0.4 0.0 0.9 0.1 0.2 0.0 0.0 0.0 COL9A2 "EDM2, MED" ENSG00000049089 "Collagen type IX alpha 2 chain" Q14055 1 40300489-40317813 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.2;pituitary gland: 108.1" "Cell type enhanced" "Detected in many" "Muller glia cells: 295.4;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 128.1" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 3.2;myeloid DC: 1.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.2;granulocytes: 3.2" "Group enriched" "Detected in many" 4 "HDLM-2: 98.6;Hep G2: 27.6;HMC-1: 90.3;THP-1: 105.0" "Low region specificity" "Detected in all" "HPA056316, HPA075286" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 510000 "Cluster 52: Eosinophils - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles Nucleoplasm "HPA056316: AB_2683099, HPA075286: AB_2732288" "unprognostic (1.42e-2)" "unprognostic (3.54e-2)" "unprognostic (8.94e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.46e-2)" "unprognostic (1.83e-3)" "unprognostic (2.06e-2)" "unprognostic (9.00e-3)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (2.26e-1)" "unprognostic (1.16e-3)" "unprognostic (4.28e-2)" "unprognostic (2.56e-1)" "unprognostic (5.89e-2)" "unprognostic (1.71e-2)" 2.2 3.4 42.6 3.7 71.5 10.9 5.9 58.9 51.1 12.1 21.6 6.5 5.8 5.0 1.7 1.6 11.4 8.5 2.2 38.2 49.7 24.6 0.9 4.3 5.9 65.9 74.1 1.3 2.3 21.0 108.1 1.1 66.2 13.7 3.1 23.1 16.3 24.2 0.2 4.6 10.4 1.4 52.0 9.8 16.5 2.6 58.6 1.8 12.2 0.3 3.1 12.1 2.0 86.2 12.0 0.3 1.8 0.8 2.6 1.3 7.8 0.0 0.0 0.6 1.3 0.4 6.8 3.4 10.0 0.3 0.0 2.0 0.1 0.0 0.3 98.6 1.4 2.0 0.8 27.6 1.5 0.9 90.3 4.8 0.0 0.1 0.0 0.7 0.0 1.5 0.1 19.8 0.0 2.7 1.2 2.1 2.2 0.0 1.2 2.3 0.0 6.9 0.0 14.3 1.4 2.3 0.1 11.8 1.3 6.6 15.0 105.0 0.1 0.0 11.6 0.2 0.4 1.4 0.2 3.4 1.0 12.3 0.6 0.0 0.1 3.2 0.0 0.2 0.0 0.2 0.1 0.0 1.2 0.2 0.0 0.0 0.5 0.2 0.3 0.1 0.1 0.0 42.6 71.5 58.9 51.1 38.2 49.7 65.9 74.1 66.2 52.0 58.6 86.2 0.5 0.0 3.3 26.1 10.8 1.0 3.0 8.5 0.0 2.0 7.1 9.7 1.0 7.2 10.0 25.8 0.0 3.2 2.5 7.2 0.0 11.7 0.2 13.6 0.9 0.6 12.7 0.4 0.3 0.8 0.6 2.1 26.0 20.0 26.1 1.6 1.1 0.0 3.4 0.0 0.3 6.6 2.0 0.3 22.4 0.9 2.1 6.4 1.8 3.7 22.1 295.4 1.0 62.4 128.1 4.9 9.6 0.0 4.0 6.1 5.0 0.3 12.9 10.9 0.0 1.3 1.8 3.4 6.2 0.2 0.6 1.4 2.7 1.8 13.4 13.4 COL9A3 "DJ885L7.4.1, EDM3, FLJ90759, IDD, MED" ENSG00000092758 "Collagen type IX alpha 3 chain" Q14050 20 62816244-62841159 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.7;choroid plexus: 34.4;thyroid gland: 25.4" "Cell type enhanced" "Detected in many" "Early spermatids: 116.6;Late spermatids: 401.9;Muller glia cells: 95.8;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 68.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 143.4;Hep G2: 59.6;SK-MEL-30: 51.1;WM-115: 57.8" "Low region specificity" "Detected in all" "HPA040125, HPA058323" Supported Approved "Nucleoplasm,Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Intermediate filaments" "HPA040125: AB_10805604, HPA058323: AB_2683679" "unprognostic (1.14e-3)" "unprognostic (2.14e-2)" "unprognostic (3.93e-1)" "unprognostic (1.21e-3)" "unprognostic (4.25e-2)" "unprognostic (2.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.24e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.67e-1)" 1.6 1.5 17.5 0.7 35.7 0.0 2.8 22.4 21.6 3.3 34.4 12.1 0.7 1.2 0.2 1.3 1.7 0.1 6.3 13.0 16.5 2.9 0.6 0.4 0.2 37.4 31.0 1.7 7.6 0.1 14.0 0.5 24.2 3.2 0.1 1.6 23.6 1.2 0.5 1.9 3.1 0.1 20.5 0.3 2.7 20.7 31.6 0.1 25.4 0.0 0.0 2.8 3.8 39.7 0.2 0.3 0.3 0.2 0.0 0.8 143.4 0.1 0.0 0.1 0.0 1.6 0.2 0.0 13.1 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.9 0.0 8.2 59.6 0.3 0.0 0.5 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.3 0.0 0.0 1.0 0.7 6.4 8.2 0.0 2.5 0.0 1.8 0.0 0.1 0.0 1.5 0.2 0.1 51.1 4.6 0.2 5.4 0.0 0.0 0.7 0.1 1.0 0.2 0.1 0.0 0.2 0.0 57.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 35.7 22.4 21.6 13.0 16.5 37.4 31.0 24.2 20.5 31.6 39.7 1.6 3.2 0.0 1.0 26.1 3.2 2.2 1.2 1.8 0.9 2.1 2.5 1.6 0.0 0.2 5.5 10.4 5.1 0.4 0.7 1.9 3.6 116.6 2.7 0.4 3.7 4.2 1.3 2.5 0.0 46.4 15.3 6.1 0.7 0.0 0.6 2.5 6.8 2.2 0.0 2.0 3.3 0.0 2.2 0.9 401.9 4.1 1.7 3.6 0.0 0.5 95.8 0.0 84.9 68.9 0.1 7.3 1.5 44.0 1.2 2.3 23.7 2.5 3.7 0.0 0.8 1.0 2.9 7.8 0.9 7.0 4.0 1.4 3.7 2.0 1.0 COP1 "CFAP78, FAP78, FLJ10416, RFWD2, RNF200" ENSG00000143207 "COP1 E3 ubiquitin ligase" Q8NHY2 1 175944831-176207286 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.1;Extravillous trophoblasts: 33.5;Syncytiotrophoblasts: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.99e-1)" "unprognostic (3.76e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (2.95e-2)" "unprognostic (4.33e-1)" "unprognostic (2.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.52e-2)" "unprognostic (9.24e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-2)" "unprognostic (6.68e-2)" "unprognostic (7.01e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" 14.2 9.5 5.9 12.0 7.1 16.8 12.7 11.4 9.1 12.1 8.4 18.1 13.8 11.8 9.8 14.2 9.4 9.5 9.8 8.5 5.9 12.4 16.6 12.5 15.7 4.6 5.0 8.7 13.2 10.5 8.0 11.2 5.0 10.1 16.7 8.6 13.1 8.5 13.6 17.5 13.9 11.0 5.7 16.7 13.7 15.6 6.1 14.9 10.6 7.4 16.8 14.7 11.9 8.8 35.3 17.5 22.1 13.8 23.0 22.6 56.1 21.7 22.0 17.7 18.6 30.0 28.1 59.4 25.8 20.9 18.9 32.3 16.9 27.0 17.7 23.7 17.0 22.6 19.4 28.0 18.9 49.2 33.0 16.8 28.9 17.6 19.8 17.9 26.6 21.7 43.9 24.9 24.8 42.5 27.0 28.2 47.4 55.8 2.0 26.1 20.4 40.2 26.8 93.7 22.6 41.6 27.8 44.9 35.9 37.4 32.1 69.1 40.4 19.4 16.1 28.3 23.4 35.3 62.7 49.8 19.1 26.7 26.9 8.5 3.0 12.0 1.9 3.7 1.4 1.7 2.0 1.4 2.1 1.5 2.7 2.0 14.1 0.6 3.4 1.1 1.7 1.0 5.9 7.1 11.4 9.1 8.5 5.9 4.6 5.0 5.0 5.7 6.1 8.8 15.8 22.4 14.5 0.0 4.4 0.0 0.0 0.0 0.0 0.0 15.4 10.9 0.0 0.0 3.1 9.2 0.0 28.1 12.2 0.0 21.5 14.8 0.0 17.9 14.6 7.2 0.0 0.0 0.0 22.7 33.5 7.4 0.0 20.1 7.6 18.1 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 21.8 0.0 0.0 3.1 0.0 0.0 22.1 4.4 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 31.3 6.7 13.8 0.0 0.0 COQ2 "CL640, FLJ26072" ENSG00000173085 "Coenzyme Q2, polyprenyltransferase" Q96H96 4 83261536-83284914 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease variant, Neurodegeneration, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 37.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 50.7;Kupffer cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056599, HPA068727" Approved Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056599: AB_2683184, HPA068727: AB_2686022" "unprognostic (8.26e-2)" "unprognostic (7.40e-3)" "unprognostic (3.95e-3)" "unprognostic (1.55e-1)" "unprognostic (9.22e-2)" "unprognostic (5.59e-2)" "unprognostic (1.26e-2)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.56e-2)" "unprognostic (3.73e-1)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (2.46e-1)" 6.0 17.0 2.8 8.0 3.2 11.8 5.8 3.5 3.3 7.9 3.6 14.2 9.5 6.3 7.5 10.4 4.4 4.3 15.0 3.0 3.5 5.6 13.6 7.9 6.4 3.6 3.5 6.5 6.5 6.0 4.0 8.4 3.8 6.6 14.2 4.0 7.8 5.0 29.1 10.8 9.1 6.9 4.1 10.1 5.5 3.5 3.9 3.6 5.7 37.5 7.1 7.9 6.5 4.9 26.1 14.7 14.1 27.4 10.5 11.9 9.7 16.1 27.0 29.7 34.4 10.5 38.7 17.2 11.7 28.4 24.6 18.6 23.9 26.0 38.7 17.2 14.8 15.3 22.3 15.4 11.7 31.3 73.5 15.9 16.3 14.2 24.8 8.9 30.7 9.7 10.0 21.4 29.3 27.4 8.6 21.7 10.9 30.6 19.9 14.1 11.4 22.1 45.4 13.8 10.3 6.3 19.0 24.5 9.2 6.7 15.4 18.8 21.0 14.6 14.6 11.1 23.4 5.7 5.2 10.2 29.5 36.8 20.2 2.1 28.8 4.0 2.7 26.8 1.9 6.2 3.0 2.5 21.1 6.9 2.1 3.2 9.8 6.7 33.5 11.2 4.1 13.6 2.8 3.2 3.5 3.3 3.0 3.5 3.6 3.5 3.8 4.1 3.9 4.9 5.4 0.0 4.2 15.7 11.5 6.6 12.4 9.8 4.6 5.9 6.3 5.6 19.5 2.8 10.7 9.2 0.0 25.4 7.1 14.0 31.3 6.7 0.8 7.6 19.5 6.1 4.8 14.1 12.8 10.8 30.0 9.0 6.6 9.2 0.0 17.2 9.3 15.0 50.7 1.7 20.1 15.3 8.2 53.2 7.9 0.8 3.7 25.2 7.2 33.7 21.8 12.6 6.2 25.6 15.6 5.4 15.4 4.9 4.3 12.6 11.0 9.9 6.2 4.8 0.0 7.3 9.7 18.1 19.7 16.7 12.6 12.4 9.6 35.5 26.7 12.9 CORO2A "IR10, WDR2" ENSG00000106789 "Coronin 2A" Q92828 9 98120975-98192637 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.2;Proximal enterocytes: 93.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 11.4;monocytes: 7.8;T-cells: 11.9" "Cell line enhanced" "Detected in many" "BEWO: 66.6;OE19: 56.4;SK-BR-3: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041161, HPA041302" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA041161: AB_10795537, HPA041302: AB_10794195" "unprognostic (4.49e-3)" "unprognostic (3.44e-2)" "unprognostic (3.14e-1)" "unprognostic (1.78e-1)" "unprognostic (3.39e-3)" "unprognostic (1.64e-1)" "unprognostic (3.73e-2)" "unprognostic (5.73e-2)" "unprognostic (2.79e-1)" "unprognostic (1.52e-1)" "unprognostic (4.50e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" "unprognostic (6.40e-3)" 1.9 1.7 1.9 4.9 1.5 14.8 4.7 4.9 3.2 6.1 0.0 17.5 34.3 1.6 0.7 15.2 4.7 18.2 0.3 1.2 2.9 1.1 3.3 7.4 2.9 3.7 3.4 0.3 0.4 2.5 4.0 2.1 4.9 14.3 12.9 1.2 6.1 1.4 0.3 9.3 35.1 2.2 0.8 3.0 11.1 9.2 4.5 5.7 1.2 0.3 5.9 12.8 7.7 1.8 8.4 2.9 0.6 2.0 1.2 1.3 66.6 0.6 0.7 2.1 3.2 19.1 1.4 0.1 9.4 1.2 3.2 23.1 7.7 12.7 1.3 6.9 1.8 0.2 11.6 17.1 2.7 7.9 0.7 0.4 15.4 1.0 18.6 0.7 0.7 10.0 6.8 3.8 0.3 6.3 1.5 7.8 8.6 56.4 2.2 6.1 0.1 0.2 1.3 23.5 1.7 2.4 4.4 45.3 1.6 15.0 5.3 12.8 0.6 0.2 9.7 0.2 2.4 0.7 4.0 0.7 0.5 2.5 2.8 11.2 1.4 11.4 2.4 2.9 5.2 0.6 3.9 3.7 0.5 0.5 2.5 3.3 1.0 1.7 7.8 0.7 11.9 1.5 1.9 1.5 4.9 3.2 1.2 2.9 3.7 3.4 4.9 0.8 4.5 1.8 2.8 12.8 27.8 0.7 3.1 6.6 18.9 47.2 14.8 2.1 8.5 4.3 1.9 28.6 46.4 0.0 4.2 10.5 2.1 76.2 0.0 4.5 2.6 15.6 11.6 6.0 7.2 0.8 11.6 5.1 42.2 2.2 36.2 19.9 0.0 38.1 0.7 3.8 6.0 1.7 10.5 15.7 20.3 12.0 2.6 3.9 0.0 10.6 0.0 1.0 1.8 0.7 2.1 0.5 0.8 22.6 19.7 0.4 1.4 15.7 93.0 1.7 35.8 1.7 0.0 1.5 3.7 0.5 3.3 29.4 9.9 15.9 10.7 0.2 36.3 30.4 CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 219.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 306.1;Kupffer cells: 290.3;Langerhans cells: 531.0;Macrophages: 266.2;monocytes: 176.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1136.9;intermediate monocyte: 953.5;myeloid DC: 1319.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1319.5;monocytes: 1136.9" "Cell line enhanced" "Detected in many" "BEWO: 190.8;RPTEC TERT1: 801.1;U-266/84: 205.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 760000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" 44.0 23.5 7.5 66.3 8.7 59.8 24.9 48.9 12.0 28.5 39.6 28.9 32.8 17.1 34.6 25.4 19.8 42.1 79.3 6.8 9.9 96.7 52.9 57.6 92.9 15.2 11.4 18.1 7.9 5.4 10.1 84.9 15.4 17.9 25.7 0.9 5.3 21.3 12.5 19.3 46.5 34.1 11.8 219.0 15.5 34.4 8.8 66.7 128.4 8.3 35.8 50.6 15.8 23.4 1.5 0.2 20.3 0.1 0.1 0.0 190.8 0.0 0.0 1.9 0.4 59.8 0.1 0.0 90.3 0.8 94.4 3.2 51.8 4.2 0.6 0.4 47.9 67.0 1.2 144.5 0.0 0.0 0.3 0.3 5.9 0.7 1.6 0.0 0.6 27.5 45.5 0.1 1.6 0.0 63.4 0.4 31.6 0.1 16.0 0.3 0.0 0.6 801.1 22.8 11.9 9.4 53.6 125.5 101.7 97.0 15.1 49.6 0.0 0.4 0.8 0.5 12.0 17.5 205.5 1.0 0.2 25.0 20.8 19.5 1136.9 5.7 2.6 953.5 3.4 1.8 1.3 1.9 1319.5 1.2 1.2 1.2 23.4 5.8 327.8 34.8 1.5 1142.7 7.5 8.7 48.9 12.0 6.8 9.9 15.2 11.4 15.4 11.8 8.8 23.4 12.3 6.4 16.0 3.3 7.2 12.5 1.3 0.7 5.7 0.0 2.6 3.4 69.1 10.0 2.5 71.7 0.0 138.0 2.1 0.2 35.2 0.5 24.7 3.7 0.3 21.1 1.8 34.1 3.7 15.6 118.3 29.4 1.1 0.6 5.1 2.3 6.8 1.1 306.1 0.0 1.7 1.2 0.0 290.3 531.0 7.6 9.3 266.2 10.6 45.9 176.8 0.2 2.1 2.0 1.3 0.8 0.4 3.0 2.9 0.5 0.4 30.6 1.5 0.4 0.0 31.0 3.0 27.1 92.8 27.2 8.8 118.5 3.3 3.6 1.2 0.9 CREB3L1 OASIS ENSG00000157613 "CAMP responsive element binding protein 3 like 1" Q96BA8 11 46277662-46321409 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.9;salivary gland: 83.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.2;Gastric mucus-secreting cells: 105.0;Glandular and luminal cells: 120.5;Intestinal goblet cells: 280.5" "Cancer enhanced" "Detected in all" "prostate cancer: 87.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 134.3;BJ hTERT+: 130.7;BJ hTERT+ SV40 Large T+: 120.6;fHDF/TERT166: 321.8;OE19: 129.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA024069, CAB026151" Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB026151: , HPA024069: AB_1854750" "unprognostic (2.46e-2)" "unprognostic (2.80e-1)" "unprognostic (1.34e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.66e-3)" "unprognostic (2.93e-1)" "unprognostic (5.41e-2)" "unprognostic (2.75e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.97e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (1.12e-2)" 8.6 15.1 4.3 8.0 3.3 0.1 10.7 0.9 4.2 43.2 2.1 41.2 27.7 20.4 2.4 3.2 5.2 25.0 15.6 7.2 3.4 2.8 1.1 14.8 0.7 1.9 5.1 9.3 133.9 2.3 10.7 26.7 4.1 42.3 43.3 0.1 83.0 26.8 4.4 5.6 30.6 13.3 1.1 3.2 68.0 3.9 8.4 1.0 4.5 4.2 4.7 21.4 15.3 2.4 0.9 0.8 1.3 26.1 81.9 77.9 0.6 134.3 130.7 120.6 83.3 13.7 0.3 0.0 0.7 321.8 8.3 0.0 1.6 0.4 66.6 0.1 1.5 2.0 0.8 0.0 113.5 0.0 1.9 75.2 0.0 68.6 2.5 109.0 1.0 0.5 11.2 0.0 102.5 0.0 0.1 0.4 17.0 129.0 13.7 0.1 18.0 0.2 0.2 0.0 0.0 0.2 0.9 3.4 0.2 23.3 0.1 4.9 0.0 62.7 18.3 48.6 83.4 0.1 0.1 0.0 75.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.3 0.9 4.2 7.2 3.4 1.9 5.1 4.1 1.1 8.4 2.4 10.3 0.0 46.4 0.3 0.6 1.5 44.4 2.6 0.0 0.0 52.0 5.1 15.9 25.8 10.0 29.5 0.0 1.2 0.1 56.8 3.9 42.0 2.1 37.2 24.1 9.0 9.1 0.0 2.1 89.2 2.3 49.4 105.0 120.5 4.5 1.9 3.3 0.0 1.9 0.0 1.0 280.5 6.1 0.0 3.5 6.6 83.6 1.0 10.6 2.8 2.0 0.0 0.0 19.6 0.1 49.2 59.8 44.4 0.2 40.4 9.5 0.7 3.6 0.0 0.0 0.7 29.3 1.0 1.5 0.6 2.3 3.4 1.8 10.7 57.7 51.3 CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Adipocytes: 165.7;Basal prostatic cells: 192.2;monocytes: 163.9;Oligodendrocyte precursor cells: 229.7;Oligodendrocytes: 734.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 198.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 198.8" "Cell line enhanced" "Detected in many" "HL-60: 62.5;Karpas-707: 25.0;U-2 OS: 25.7;U-2197: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Plasma membrane" "HPA050020: AB_2680993, HPA061622: AB_2684569" "unprognostic (3.59e-2)" "unprognostic (3.80e-1)" "unprognostic (1.06e-1)" "unprognostic (6.46e-2)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.01e-3)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-1)" "unprognostic (4.91e-3)" "unprognostic (6.61e-2)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" 10.5 1.3 6.3 7.9 20.5 6.1 5.0 6.8 12.7 1.7 0.0 3.5 0.9 8.4 2.8 3.5 2.2 11.4 5.3 9.6 19.9 3.0 1.8 6.1 0.9 19.7 14.6 0.7 3.2 0.2 1.1 3.7 15.8 1.2 1.7 1.3 3.5 1.0 3.2 2.9 2.2 4.7 2.9 7.4 1.4 0.7 23.0 0.7 1.8 4.0 0.8 4.4 2.2 35.0 0.1 0.6 7.3 0.4 0.4 10.3 0.3 0.7 1.6 4.4 6.6 4.2 2.7 18.9 1.3 1.8 4.5 0.7 0.2 6.4 13.8 0.0 5.0 20.4 4.2 0.4 0.4 62.5 0.7 1.3 1.2 18.9 20.1 0.9 3.0 0.1 2.4 25.0 1.5 0.1 0.1 0.0 9.1 0.1 7.4 0.5 6.8 0.5 9.0 2.0 0.7 5.2 0.3 0.4 2.2 10.0 0.2 1.5 0.8 8.6 25.7 28.7 8.5 1.5 4.5 0.2 9.4 0.3 14.8 0.1 29.9 0.0 0.0 9.7 0.0 1.9 0.0 0.0 18.2 0.1 0.0 0.0 198.8 0.0 3.9 0.3 0.0 7.0 6.3 20.5 6.8 12.7 9.6 19.9 19.7 14.6 15.8 2.9 23.0 35.0 165.7 6.4 7.2 10.7 3.2 21.9 192.2 8.2 13.1 1.3 10.7 8.9 16.8 17.2 6.3 12.9 0.0 4.0 0.8 0.0 1.9 74.2 0.4 41.0 56.3 31.3 0.0 0.4 17.0 27.4 13.4 108.0 3.1 69.7 14.0 0.6 14.3 0.5 8.3 5.0 22.2 0.0 6.1 47.4 118.2 1.6 5.9 75.8 30.2 22.5 163.9 14.3 4.1 229.7 734.9 22.5 0.0 0.4 3.2 44.9 0.0 25.6 4.7 0.9 19.7 143.5 31.8 12.6 7.3 12.0 13.2 24.8 3.1 2.6 0.0 35.1 CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355778-36551135 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 163.8" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Hepatic stellate cells: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 466.5;fHDF/TERT166: 462.5;TIME: 651.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA000556: AB_1078567" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (6.39e-2)" "unprognostic (3.17e-3)" "unprognostic (3.88e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (4.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.51e-4)" "unprognostic (1.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.67e-2)" 88.3 14.6 27.0 18.8 28.1 3.5 58.9 9.4 23.5 26.7 51.4 28.7 14.9 26.6 16.7 30.5 34.4 32.2 34.5 20.3 28.8 70.0 16.0 50.1 14.8 23.5 21.9 36.9 23.5 29.2 7.4 163.8 21.2 25.8 23.2 29.5 31.1 32.6 50.1 27.2 18.2 35.7 22.1 47.1 17.5 12.4 36.1 9.9 33.8 36.5 8.7 38.9 22.2 17.1 100.9 75.4 15.2 17.5 69.1 78.0 125.0 466.5 244.7 255.4 133.4 95.3 34.2 0.2 297.9 462.5 166.1 42.8 11.4 75.2 206.5 1.1 8.7 3.2 96.7 55.5 221.5 2.2 0.6 110.1 55.2 102.4 182.4 238.4 361.9 1.9 4.7 0.7 271.6 9.2 0.2 1.2 11.9 5.2 22.1 5.4 19.6 15.5 159.8 41.1 1.8 0.2 81.5 26.4 3.4 56.2 72.3 2.0 651.1 321.7 116.1 40.4 229.1 25.5 0.5 0.9 94.7 0.4 100.8 1.4 0.1 0.5 0.6 0.0 0.4 0.3 0.2 0.3 0.1 0.2 0.0 0.3 0.2 0.4 0.6 2.1 0.2 0.0 27.0 28.1 9.4 23.5 20.3 28.8 23.5 21.9 21.2 22.1 36.1 17.1 262.9 12.8 43.3 100.2 5.4 66.0 38.5 30.1 43.9 12.0 55.6 72.9 34.4 47.1 26.5 132.4 2.1 111.9 27.1 49.5 3.9 33.5 1.0 37.1 27.7 159.8 31.8 10.7 85.1 2.6 40.6 41.0 10.2 75.9 1.3 27.4 207.1 3.6 27.7 0.0 57.5 37.7 36.7 7.7 32.5 2.0 19.0 8.2 39.2 135.9 7.1 18.5 6.2 65.9 17.2 26.5 30.9 19.9 6.9 75.5 11.5 38.4 28.9 42.5 46.0 18.4 164.6 2.1 9.4 22.0 30.1 173.5 17.1 5.7 33.2 58.3 CRISPLD1 "Cocoacrisp, DKFZp762F133, LCRISP1" ENSG00000121005 "Cysteine rich secretory protein LCCL domain containing 1" Q9H336 8 74984505-75034558 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 29.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 36.1;Endometrial ciliated cells: 62.2;Oligodendrocyte precursor cells: 81.4" "Cancer enhanced" "Detected in many" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 134.4;SH-SY5Y: 72.0;SuSa: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024725 Uncertain "Secreted - unknown location" NA NA 8200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA024725: AB_1847238" "unprognostic (2.16e-1)" "unprognostic (5.88e-2)" "unprognostic (4.01e-2)" "unprognostic (3.78e-2)" "unprognostic (3.85e-2)" "unprognostic (1.65e-1)" "unprognostic (2.09e-4)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (5.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (7.39e-3)" "unprognostic (2.38e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" 2.7 1.3 3.9 2.5 4.0 1.5 29.4 3.4 3.1 6.3 3.4 2.7 0.7 8.6 4.9 5.0 7.4 10.0 8.8 4.3 8.0 2.1 2.1 2.3 2.8 5.8 10.4 5.7 2.4 19.3 1.2 7.8 8.3 24.6 1.6 3.1 19.3 2.6 0.5 2.3 1.2 7.0 6.3 2.0 0.9 3.8 4.1 9.4 15.1 1.2 1.1 2.5 1.1 10.7 0.0 1.7 134.4 0.0 0.0 0.0 4.5 0.0 0.0 1.6 1.9 0.8 0.0 0.0 19.0 0.0 2.2 0.1 11.3 0.1 0.0 0.1 5.2 0.2 5.1 0.0 3.0 0.0 1.0 7.2 0.3 0.1 1.0 16.6 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.2 13.9 0.0 5.0 0.0 18.5 0.2 0.0 0.0 0.8 72.0 0.0 0.1 8.0 27.5 10.4 6.4 0.0 3.8 19.6 0.2 0.5 2.4 0.9 0.0 4.6 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.9 4.0 3.4 3.1 4.3 8.0 5.8 10.4 8.3 6.3 4.1 10.7 1.0 3.2 0.0 12.7 0.0 0.8 6.1 1.4 17.6 1.6 10.3 36.1 0.4 0.0 5.4 1.8 0.0 22.7 0.3 0.0 0.0 0.0 15.3 62.2 4.9 3.2 0.0 3.0 15.7 0.0 3.8 9.2 0.0 22.4 3.8 1.8 23.6 0.1 2.0 0.0 11.1 0.0 0.0 0.9 0.0 1.5 4.1 0.4 7.2 1.9 0.0 8.8 0.0 81.4 0.9 0.0 0.0 1.5 0.0 9.4 0.0 0.2 22.5 0.9 0.0 0.4 1.5 1.3 6.0 2.5 1.0 12.0 0.4 6.3 0.0 2.3 CSGALNACT1 "ChGn, CSGalNAcT-1, FLJ11264" ENSG00000147408 "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" Q8TDX6 8 19404161-19758029 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 86.7" "Cell type enhanced" "Detected in many" "Astrocytes: 494.3;Excitatory neurons: 144.4;Granulosa cells: 214.1;Microglial cells: 224.9;Oligodendrocyte precursor cells: 355.9" "Cancer enhanced" "Detected in all" "prostate cancer: 22.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 62.6" "Group enriched" "Detected in all" 5 "B-cells: 44.5;granulocytes: 24.9;T-cells: 62.6" "Cell line enhanced" "Detected in many" "A549: 57.8;BJ hTERT+: 32.3;GAMG: 22.9;RPTEC TERT1: 39.6;U-2197: 36.8;U-87 MG: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068462 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Golgi apparatus" "HPA068462: " "unprognostic (8.90e-2)" "unprognostic (1.57e-2)" "unprognostic (4.66e-2)" "unprognostic (2.58e-1)" "unprognostic (6.03e-2)" "unprognostic (3.17e-3)" "unprognostic (9.78e-2)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (1.46e-3)" "unprognostic (1.02e-2)" 19.4 12.5 20.3 8.8 15.7 11.1 7.4 4.8 18.3 18.0 0.7 4.7 3.5 7.0 5.4 31.2 11.8 16.1 35.8 16.3 11.5 6.0 2.8 11.7 7.6 6.3 11.2 57.0 7.9 11.4 3.0 38.8 7.6 31.8 2.5 2.5 6.8 9.8 5.8 4.8 4.7 12.3 6.7 8.7 6.9 2.8 8.9 11.7 86.7 11.0 8.8 23.4 8.1 10.7 2.1 57.8 0.5 0.0 9.3 2.1 7.9 1.4 32.3 0.3 0.3 3.1 1.0 0.0 0.3 0.0 22.9 0.7 0.0 0.0 0.4 7.5 0.4 0.2 16.2 1.9 4.1 0.0 0.1 0.9 1.6 0.7 0.3 0.4 11.6 0.2 0.0 0.1 0.1 2.6 2.9 0.2 0.3 8.3 1.7 0.3 0.1 0.0 39.6 1.6 0.2 0.3 17.2 6.9 2.4 1.5 0.1 0.4 1.0 1.1 1.3 36.8 0.9 0.3 0.0 0.0 26.0 3.4 11.4 0.1 2.9 24.9 5.6 0.1 0.6 44.5 25.7 8.5 2.8 15.9 44.6 11.6 15.6 8.4 0.4 4.2 62.6 11.7 20.3 15.7 4.8 18.3 16.3 11.5 6.3 11.2 7.6 6.7 8.9 10.7 33.3 3.2 1.1 494.3 27.3 4.5 7.4 0.2 0.6 0.3 4.1 0.8 45.8 0.0 0.9 12.9 10.4 1.9 6.2 0.0 1.9 5.7 6.9 7.5 1.2 38.5 3.0 3.2 144.4 1.7 14.6 20.9 2.0 2.0 0.0 214.1 26.7 0.2 15.8 18.5 76.5 0.0 16.2 27.4 6.5 7.4 5.3 14.1 12.4 224.9 3.5 1.0 6.2 355.9 4.6 3.1 0.0 12.0 21.3 21.8 0.0 0.1 1.5 1.0 6.6 2.1 12.0 0.7 0.1 0.5 3.1 8.3 9.6 77.0 0.1 2.8 CSMD1 "KIAA1890, PPP1R24" ENSG00000183117 "CUB and Sushi multiple domains 1" Q96PZ7 8 2935353-4994972 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 10.7" "Group enriched" "Detected in some" 20 "Excitatory neurons: 4868.4;Inhibitory neurons: 3913.1;Oligodendrocyte precursor cells: 4521.8" "Cancer enhanced" "Detected in some" "testis cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.9;U-2 OS: 2.2;U-266/70: 2.2;U-266/84: 2.1;U-698: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074707 Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA074707: AB_2686707" "unprognostic (6.32e-2)" "unprognostic (4.23e-2)" "unprognostic (2.37e-1)" "unprognostic (1.67e-3)" "unprognostic (5.72e-2)" "unprognostic (4.26e-2)" "unprognostic (1.02e-2)" "unprognostic (4.66e-2)" "unprognostic (7.69e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-1)" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (2.74e-2)" "unprognostic (5.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.11e-1)" 0.1 0.0 3.5 0.0 5.8 0.0 0.2 0.0 10.7 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 5.8 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.0 1.6 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.6 0.0 2.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.2 0.0 0.0 2.2 2.1 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 0.0 10.7 5.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.6 0.0 0.5 108.4 0.0 0.3 0.0 0.0 2.2 15.0 1.0 0.9 2.2 0.0 0.6 1.8 0.0 3.4 0.0 0.1 0.0 0.0 52.5 1.5 0.3 2.2 0.0 0.0 4868.4 0.0 1.3 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 3913.1 0.1 0.0 0.0 0.7 15.0 0.3 0.2 0.0 220.2 0.7 0.5 0.0 4521.8 135.2 0.0 0.1 0.4 0.0 0.0 0.0 1.2 9.7 0.6 0.0 0.2 0.5 10.2 5.3 1.0 0.1 3.6 0.1 2.8 0.0 0.1 CSNK2A1 "Cka1, Cka2" ENSG00000101266 "Casein kinase 2 alpha 1" P68400 20 472498-543835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020680, HPA059206, HPA061698, CAB069395" Supported Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "CAB020680: , CAB069395: AB_1611912, HPA059206: AB_2683948, HPA061698: AB_2732667" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (5.44e-2)" "unprognostic (8.28e-3)" "unprognostic (3.62e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (4.11e-6)" "unprognostic (4.08e-2)" "unprognostic (3.89e-1)" "unprognostic (6.88e-2)" "unprognostic (1.94e-2)" "unprognostic (1.16e-1)" "unprognostic (8.58e-2)" "unprognostic (1.50e-1)" "unprognostic (4.47e-1)" "unprognostic (9.53e-2)" "unprognostic (7.37e-2)" 36.1 32.6 20.9 38.6 23.2 34.0 35.9 28.2 29.6 36.5 29.3 48.3 39.1 35.8 26.6 50.0 39.9 31.3 54.0 25.7 21.0 41.0 31.8 31.6 41.2 20.6 21.1 41.5 46.9 59.1 21.2 42.4 21.1 35.8 40.7 32.9 41.1 37.7 110.5 34.2 40.5 39.1 18.8 30.2 49.5 65.2 22.3 51.6 39.6 86.4 46.6 47.4 28.5 27.3 209.5 170.4 152.9 96.0 61.1 103.8 103.5 117.9 116.1 125.8 139.5 178.5 120.0 179.1 74.2 90.1 179.1 147.8 162.1 167.4 187.2 62.6 57.7 247.3 44.7 177.7 102.5 228.1 51.3 99.5 173.3 105.8 316.0 122.2 139.5 146.4 248.9 112.6 123.8 64.2 262.0 73.7 227.4 173.4 97.6 149.8 140.5 140.9 112.9 128.5 163.9 132.3 97.2 184.0 174.8 120.7 120.4 83.9 142.7 136.0 118.4 90.0 178.5 120.6 311.8 174.1 65.8 119.5 138.6 40.5 23.8 28.7 18.2 32.3 22.4 23.0 18.0 17.6 31.5 22.5 17.9 17.4 14.9 25.1 33.5 25.7 20.4 20.8 20.9 23.2 28.2 29.6 25.7 21.0 20.6 21.1 21.1 18.8 22.3 27.3 50.7 64.1 84.6 51.9 46.1 41.0 40.0 43.8 45.5 49.4 42.1 36.1 59.4 41.5 75.8 44.1 31.3 42.2 50.5 43.5 41.1 68.5 135.5 67.6 77.0 44.5 35.2 59.3 65.6 50.6 54.4 46.3 40.2 75.7 63.8 108.6 27.1 31.1 33.2 60.6 69.3 41.8 46.8 39.2 30.3 140.0 41.0 45.3 14.2 51.5 61.7 38.6 37.0 73.9 73.6 66.6 34.4 36.9 49.6 57.2 43.2 68.8 65.5 27.8 52.6 43.6 56.8 94.2 68.7 52.3 50.2 61.4 38.9 81.2 40.6 59.4 CSPG5 NGC ENSG00000114646 "Chondroitin sulfate proteoglycan 5" O95196 3 47562238-47580792 "Predicted membrane proteins" "Differentiation, Growth regulation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 83.2;choroid plexus: 65.2;retina: 28.3" "Group enriched" "Detected in some" 4 "Astrocytes: 67.6;Muller glia cells: 94.7;Oligodendrocyte precursor cells: 233.7" "Cancer enriched" "Detected in many" 19 "glioma: 48.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 32.6;HEK 293: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049529, HPA067818, HPA071779" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Mitochondria "HPA049529: AB_2680805, HPA067818: AB_2685905, HPA071779: AB_2686446" "unprognostic (2.68e-1)" "unprognostic (2.11e-1)" "unprognostic (8.87e-2)" "unprognostic (3.12e-2)" "unprognostic (2.88e-1)" "unprognostic (7.66e-2)" "unprognostic (5.05e-4)" "unprognostic (1.40e-1)" "unprognostic (3.82e-1)" "prognostic favorable (2.14e-4)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (3.41e-4)" "unprognostic (8.08e-2)" "unprognostic (1.01e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" 0.9 0.8 58.3 0.2 62.4 0.1 0.6 33.6 83.2 0.3 65.2 1.1 0.0 0.3 0.1 0.3 0.3 0.1 0.5 62.5 49.7 0.2 0.2 3.2 0.2 41.2 45.6 0.2 0.3 0.3 1.7 0.8 45.8 0.4 0.2 28.3 0.3 0.0 0.5 1.1 0.3 0.4 37.0 0.0 0.4 1.9 48.0 0.1 0.4 0.0 0.1 0.1 0.2 46.1 0.3 1.7 32.6 5.7 0.6 0.0 0.9 0.6 0.1 1.2 0.3 0.3 2.0 0.1 2.5 0.1 2.4 0.5 2.7 0.3 0.3 0.0 8.8 0.5 1.4 0.0 0.0 0.4 1.4 0.0 1.1 0.1 0.0 0.9 0.1 1.1 6.6 0.3 0.1 1.5 0.2 0.4 3.1 2.4 3.3 0.5 0.2 0.7 1.4 1.1 3.4 1.5 2.1 4.1 0.1 0.9 1.6 3.1 0.3 0.1 6.5 0.1 1.9 0.8 0.8 0.0 0.5 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.3 62.4 33.6 83.2 62.5 49.7 41.2 45.6 45.8 37.0 48.0 46.1 0.7 3.2 2.0 67.6 0.1 0.8 0.1 0.0 0.0 28.6 2.2 1.8 1.3 0.0 0.0 0.0 6.2 0.2 0.0 0.5 0.0 0.2 2.0 0.6 0.6 0.3 1.8 0.0 18.6 0.0 0.2 0.5 0.0 2.0 0.0 6.1 0.0 0.5 0.2 6.7 25.0 0.3 0.0 0.0 0.2 0.6 0.3 0.2 0.0 7.5 0.0 94.7 0.0 233.7 9.9 0.4 0.1 0.0 0.0 0.2 0.0 0.1 0.0 22.7 0.0 0.8 0.8 13.5 3.3 0.0 0.6 0.1 0.2 0.2 0.4 0.1 CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in many" "Muller glia cells: 185.7;Suprabasal keratinocytes: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Vesicles" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" 34.4 11.1 29.7 11.2 28.2 22.4 35.2 37.3 31.2 59.2 13.1 15.0 18.8 11.8 77.4 177.7 12.5 10.3 43.8 29.5 30.0 17.6 15.7 26.4 8.7 33.8 29.0 14.6 35.9 10.9 19.7 28.2 36.4 24.5 10.2 27.5 53.1 14.1 39.0 434.9 14.9 10.9 27.1 9.3 22.8 27.0 37.5 19.6 21.0 22.3 25.1 13.3 85.1 27.3 74.8 10.9 65.9 50.4 9.8 16.2 21.1 14.4 25.2 20.9 13.3 5.4 92.6 22.9 41.0 18.7 21.6 37.3 7.7 85.9 9.6 58.0 11.9 14.9 3.4 69.3 20.3 11.3 8.4 18.2 83.5 26.7 27.0 17.7 57.2 42.4 26.8 10.5 13.0 45.6 25.3 41.6 35.0 60.0 18.7 28.4 19.3 14.7 10.7 25.2 72.1 45.4 32.9 29.4 44.4 22.3 36.3 27.2 37.7 13.4 16.4 20.4 32.2 22.9 32.5 27.0 5.0 56.6 54.5 2.6 5.2 13.8 2.6 1.8 1.6 1.7 1.3 2.1 6.4 1.5 1.3 1.2 3.7 8.6 1.2 2.0 1.3 2.6 29.7 28.2 37.3 31.2 29.5 30.0 33.8 29.0 36.4 27.1 37.5 27.3 150.6 28.9 13.9 30.0 9.6 103.1 42.3 16.1 40.5 9.0 39.9 33.3 14.0 24.3 17.0 18.4 8.4 71.3 23.5 20.5 33.2 20.9 116.3 20.0 17.9 42.7 49.1 20.0 18.0 18.7 43.2 15.7 30.1 38.5 0.0 27.2 20.0 25.6 58.0 16.8 14.1 37.5 12.2 43.0 97.4 34.8 14.9 38.3 48.0 12.2 33.6 185.7 71.1 17.1 24.1 37.6 28.3 23.0 13.3 53.5 28.6 30.5 5.2 12.8 46.0 15.0 24.5 72.1 43.6 154.0 291.5 48.4 17.2 14.3 28.6 60.5 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1078.9;Langerhans cells: 983.5;Macrophages: 652.3;monocytes: 723.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 542.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 178.1 117.8 18.9 208.8 21.8 99.8 137.0 20.5 32.0 92.1 59.6 173.8 215.4 87.3 13.4 53.1 88.9 89.4 152.6 15.3 33.9 125.6 356.4 233.3 271.5 31.6 23.5 71.0 89.4 91.8 112.5 118.7 27.9 87.8 77.1 4.1 181.0 66.3 58.7 58.5 226.0 97.9 26.2 234.4 88.2 24.6 47.2 57.1 122.3 54.6 91.3 146.3 69.0 45.4 205.4 139.8 1.1 1.1 114.2 124.2 106.5 291.0 225.4 187.4 152.3 231.6 324.6 96.5 213.9 542.1 0.5 160.1 51.4 257.5 30.2 362.1 13.6 80.3 169.0 0.8 137.3 9.0 331.0 130.9 127.8 83.1 62.4 34.8 281.3 1.1 74.0 48.7 90.0 1.1 1.3 70.6 11.5 43.5 158.2 2.9 0.4 135.7 86.3 25.5 2.7 1.7 222.4 258.4 0.8 19.5 131.9 148.4 420.5 1.4 161.8 209.0 2.0 253.7 172.0 18.2 2.8 207.9 0.4 1.2 1.5 1.6 0.6 1.4 0.4 1.1 0.6 0.4 1.1 1.4 0.7 0.8 1.6 0.5 2.9 1.8 0.3 0.7 18.9 21.8 20.5 32.0 15.3 33.9 31.6 23.5 27.9 26.2 47.2 45.4 132.1 16.0 5.3 5.9 119.8 50.3 64.5 33.8 24.5 6.7 67.4 99.6 21.7 62.9 14.1 71.7 0.0 38.2 104.8 303.6 23.5 176.0 3.5 52.9 47.7 82.2 27.1 63.3 5.3 42.4 104.8 71.5 19.4 71.3 10.8 68.4 62.8 363.0 1078.9 11.8 3.0 56.6 26.4 334.0 983.5 6.0 13.1 652.3 101.4 23.4 723.6 58.6 21.6 2.5 2.5 82.6 217.5 13.9 96.3 50.6 339.8 90.0 18.8 5.0 46.0 67.5 74.5 3.7 4.8 14.5 41.5 41.3 33.4 3.3 99.7 52.7 CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 323.4;Proximal enterocytes: 263.0;Suprabasal keratinocytes: 343.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 93.4;Hep G2: 63.0;NTERA-2: 109.1;RT4: 104.4" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted - unknown location" NA NA 18000 "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" 3.6 2.9 7.0 2.8 8.7 2.6 9.8 6.6 10.8 7.7 22.8 22.5 42.3 5.3 15.2 14.5 10.6 18.3 9.3 8.9 7.1 8.3 49.3 13.6 0.7 10.4 6.8 0.4 15.8 6.8 4.7 0.3 9.3 15.1 25.6 4.9 15.4 14.2 0.4 53.4 42.6 3.3 9.7 2.4 30.9 12.5 7.3 1.5 22.1 0.0 4.1 25.6 10.9 17.7 16.8 9.0 44.6 0.1 0.0 0.0 26.7 0.2 0.2 0.7 2.7 93.4 14.6 6.2 19.7 0.0 13.3 28.1 22.8 6.2 1.0 9.3 19.0 0.1 24.1 63.0 2.9 1.8 0.1 0.0 24.6 1.3 0.4 10.8 9.0 5.5 0.3 0.4 0.0 1.1 3.7 0.1 109.1 15.2 0.0 0.1 15.2 12.5 38.7 104.4 18.5 12.3 10.9 12.6 6.7 45.8 25.4 0.3 0.5 0.2 25.8 0.4 6.6 4.5 7.7 0.4 3.6 0.1 0.6 1.0 0.1 0.1 0.1 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.6 0.2 0.3 0.2 0.0 0.0 0.1 0.2 7.0 8.7 6.6 10.8 8.9 7.1 10.4 6.8 9.3 9.7 7.3 17.7 0.2 141.1 79.0 2.6 1.0 323.4 172.7 110.6 132.6 16.9 58.6 28.2 29.8 161.5 106.6 103.0 27.1 0.8 0.3 238.4 5.9 130.0 5.3 118.9 8.3 4.8 80.8 9.9 60.4 93.7 0.2 8.6 94.3 128.9 5.7 1.1 47.8 127.7 0.6 0.0 43.0 107.5 81.4 22.9 13.1 7.7 2.1 3.3 23.2 40.3 0.7 13.4 0.0 78.9 161.4 93.4 155.3 0.0 1.6 125.1 263.0 4.0 85.6 11.2 6.6 0.2 5.3 6.4 24.5 117.0 343.8 0.7 4.3 0.5 107.0 202.7 CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3435.4;Basal squamous epithelial cells: 3284.9;Breast myoepithelial cells: 1544.3;Fibroblasts: 2220.8;Glandular and luminal cells: 1201.1;Proximal tubular cells: 3662.8;Suprabasal keratinocytes: 2115.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HAP1: 61.6;hTCEpi: 79.9;RPTEC TERT1: 222.2;SuSa: 115.2;U-2 OS: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 33: Fibroblasts - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" 366.1 5.2 77.6 76.2 84.5 0.6 229.1 70.6 102.7 166.3 74.8 152.4 214.0 6.9 66.6 92.9 32.9 19.8 14.0 83.7 73.8 345.6 58.5 7.4 90.7 72.4 91.0 5.5 11.6 1.9 122.0 170.7 72.4 10.1 181.3 17.5 293.5 17.6 81.1 780.3 247.0 6.3 68.7 87.5 107.3 3.7 90.2 26.6 55.2 36.5 128.5 76.6 96.3 77.9 0.0 0.0 2.7 0.0 0.2 0.2 0.7 2.9 0.8 0.2 0.0 0.0 9.1 0.0 2.7 0.1 3.8 0.2 61.6 1.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 79.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 4.0 0.0 0.0 0.2 0.0 1.1 222.2 0.0 1.1 0.7 0.2 0.2 0.0 115.2 0.1 0.0 0.0 0.1 84.9 0.4 0.1 0.3 0.0 0.0 1.4 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 77.6 84.5 70.6 102.7 83.7 73.8 72.4 91.0 72.4 68.7 90.2 77.9 123.8 0.0 1.1 32.7 13.1 3435.4 14.4 276.9 3284.9 245.7 47.5 1544.3 4.1 0.0 5.1 283.3 0.0 35.9 6.1 0.0 563.4 0.0 0.8 45.0 140.8 45.9 0.0 0.0 1.0 0.0 25.4 2220.8 0.5 1201.1 0.0 0.0 43.5 0.2 63.6 6.7 150.8 0.0 240.1 0.9 887.9 1.3 20.8 35.3 439.4 8.4 0.0 6.7 0.0 4.5 4.2 0.1 0.0 0.4 13.3 10.6 0.0 3662.8 2.1 19.0 0.0 889.8 99.2 0.4 5.2 69.3 2115.0 77.2 43.4 0.3 0.1 9.3 CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136118149 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.1;lymphoid tissue: 549.3" "Cell type enhanced" "Detected in many" "B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" 51.8 184.5 11.8 297.9 11.4 1175.1 39.6 14.6 23.8 36.1 20.1 33.2 12.6 35.2 5.5 34.9 64.9 84.5 21.8 10.6 19.7 29.0 52.4 95.5 383.8 24.3 12.8 12.9 10.0 12.3 32.6 57.5 18.2 34.1 48.6 7.8 30.2 11.8 5.2 9.8 246.5 28.1 16.7 346.5 64.0 4.0 15.2 491.2 36.7 12.0 549.3 99.3 26.9 32.3 0.8 0.3 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 580.8 1.8 0.0 0.4 0.7 1.7 0.0 0.0 29.6 6.9 35.1 84.3 0.0 0.0 81.5 60.7 0.0 0.0 0.0 0.0 0.0 54.5 323.6 1.0 302.1 0.0 1.5 538.9 72.8 9.3 45.4 2.9 281.0 62.6 102.5 4.5 0.0 30.9 26.1 0.6 2.0 0.3 2.9 0.7 156.7 8.1 0.0 2.0 0.5 0.4 648.5 116.7 677.4 0.1 131.8 0.1 87.0 28.5 117.8 83.8 15.6 67.3 115.6 76.5 79.6 25.7 166.2 113.1 109.5 143.3 17.2 9.1 63.7 76.1 51.9 11.8 11.4 14.6 23.8 10.6 19.7 24.3 12.8 18.2 16.7 15.2 32.3 32.0 16.0 42.2 8.5 1446.9 41.0 5.7 0.3 9.6 8.6 46.1 42.2 5.2 11.5 4.4 3.7 0.0 1.5 1015.1 1.1 13.7 5.1 1.2 20.0 8.9 67.6 1.8 67.5 0.0 0.9 4.2 28.9 52.0 71.0 12.6 9.0 29.6 9.1 159.9 0.0 0.2 2.0 10.2 270.0 486.2 2.9 1.5 513.6 113.8 3.7 189.2 1.0 153.5 0.0 2.0 2.3 1.1 2.6 534.2 3.2 0.0 3.2 2.4 0.8 46.0 99.1 23.1 0.5 7.8 8.5 35.7 6.3 1436.5 4.6 1.8 4.5 CYB5B CYB5-M ENSG00000103018 "Cytochrome b5 type B" O43169 16 69424619-69466264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 318.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007893 Approved Approved "Endoplasmic reticulum,Centriolar satellite,Cytosol" NA NA 99000 "Cluster 44: Non-specific - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "Centriolar satellite, Cytosol" "HPA007893: AB_1847369" "unprognostic (1.13e-1)" "unprognostic (4.47e-2)" "unprognostic (9.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (2.87e-3)" "unprognostic (4.35e-3)" "unprognostic (3.87e-1)" "unprognostic (1.44e-2)" "unprognostic (1.52e-2)" "unprognostic (3.10e-1)" "prognostic favorable (6.38e-5)" "unprognostic (9.69e-3)" "unprognostic (4.66e-2)" "unprognostic (3.78e-2)" "unprognostic (1.30e-2)" 60.2 318.0 52.3 51.4 53.9 20.9 50.4 46.0 69.9 45.8 43.6 92.6 69.5 49.3 72.8 59.3 58.2 45.4 58.0 56.9 51.2 71.9 83.8 54.1 68.8 50.7 48.1 44.0 40.1 77.7 28.6 73.8 50.6 47.6 116.0 49.4 36.3 48.3 65.8 45.8 67.8 61.6 44.7 49.6 49.3 38.6 52.3 74.3 54.1 78.2 76.9 80.4 38.2 48.4 186.2 576.4 232.9 144.9 105.1 139.3 99.5 162.3 224.1 266.0 249.2 406.1 221.3 168.0 159.3 157.9 216.0 214.5 224.4 235.0 300.0 90.2 85.5 81.2 97.1 479.1 154.7 169.1 172.4 120.9 116.3 315.9 149.6 111.8 254.7 190.5 133.6 78.4 165.2 241.2 278.9 204.1 173.5 171.4 78.4 260.0 128.7 184.3 359.3 208.7 135.7 69.7 431.6 82.0 142.2 119.0 159.0 133.2 115.9 152.2 124.5 102.2 145.5 94.7 227.0 516.6 157.0 138.0 180.0 121.1 57.6 71.5 103.8 80.0 85.0 68.8 76.9 81.8 69.8 63.1 62.8 75.5 17.1 96.4 59.7 124.2 134.6 105.6 52.3 53.9 46.0 69.9 56.9 51.2 50.7 48.1 50.6 44.7 52.3 48.4 36.2 44.8 46.8 44.7 47.2 49.8 49.2 84.0 66.0 22.8 28.6 26.0 25.0 30.0 51.4 62.5 6.2 159.8 66.7 112.7 78.2 66.2 18.8 56.4 33.3 61.7 23.4 38.7 40.9 70.4 94.1 38.4 27.5 87.7 60.2 36.6 43.9 54.9 64.8 30.3 30.4 76.6 83.4 30.1 57.5 22.7 44.4 33.4 62.2 24.4 55.8 63.0 96.8 23.6 39.4 70.5 78.8 44.4 28.1 34.9 75.9 62.9 49.5 31.6 46.0 22.2 36.5 48.1 46.6 44.9 42.3 59.8 54.1 84.8 61.6 50.4 CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643289-88651054 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 742.0;lymphoid tissue: 693.1" "Cell type enhanced" "Detected in many" "dendritic cells: 1632.1;Hofbauer cells: 2171.9;Kupffer cells: 1734.2;Macrophages: 1682.8;monocytes: 1688.5;NK-cells: 1805.4;Plasma cells: 1990.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 733.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 1058.3;RPMI-8226: 1631.2;THP-1: 1231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009492 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009492: AB_2090309" "prognostic favorable (8.19e-4)" "unprognostic (1.05e-1)" "unprognostic (8.32e-2)" "prognostic favorable (4.75e-5)" "unprognostic (2.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.91e-1)" "unprognostic (5.22e-2)" "unprognostic (2.57e-2)" "unprognostic (1.63e-2)" 149.9 68.0 40.3 344.4 41.8 742.0 93.3 46.0 58.0 81.9 62.4 200.9 196.6 60.8 38.5 80.9 95.4 122.5 93.2 38.6 55.0 187.7 71.5 234.6 333.8 73.8 49.3 40.0 108.6 13.4 40.6 54.9 64.1 75.2 79.9 1.8 116.7 26.6 41.8 39.4 245.3 51.3 65.4 693.1 236.0 10.4 62.4 87.1 136.5 19.9 192.8 144.6 74.1 92.2 2.5 663.0 2.6 1.5 1.3 0.4 329.5 155.7 77.3 39.3 24.1 447.2 819.6 510.5 420.7 56.4 0.0 250.5 21.4 0.9 5.8 146.1 564.1 99.0 217.7 694.9 75.7 156.3 397.6 80.7 0.0 1.6 0.3 1.9 23.9 103.6 278.5 567.5 3.2 1058.3 147.9 822.3 106.2 248.7 1.5 437.9 1.6 1631.2 324.9 490.9 84.2 76.5 482.7 78.8 138.5 60.8 1.4 1231.3 129.8 1.5 6.1 1.8 2.2 362.9 459.9 543.6 195.5 464.9 53.4 120.2 103.8 733.7 76.7 150.1 55.8 109.8 36.7 70.4 107.0 110.7 28.9 36.7 192.3 36.4 143.3 196.3 41.2 47.3 40.3 41.8 46.0 58.0 38.6 55.0 73.8 49.3 64.1 65.4 62.4 92.2 157.8 16.0 12.4 0.0 1290.9 119.4 233.4 420.8 53.5 0.4 131.7 133.2 12.8 368.9 487.1 285.1 2.1 45.3 1632.1 807.2 127.2 636.8 4.2 219.5 137.5 137.1 230.5 162.7 0.2 155.3 299.0 184.8 285.4 312.5 279.0 104.3 317.0 23.9 2171.9 0.0 0.2 540.3 233.9 1734.2 1370.8 14.0 50.1 1682.8 1152.6 32.8 1688.5 1.6 1805.4 1.0 0.2 682.8 1045.8 21.4 1990.6 191.8 390.4 1057.4 529.7 2.7 59.2 44.0 164.3 0.9 15.6 75.2 85.7 118.2 838.6 20.5 805.2 436.9 CYP39A1 ENSG00000146233 "Cytochrome P450 family 39 subfamily A member 1" Q9NYL5 6 46549580-46652830 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 99.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 62.9;Late spermatids: 20.1" "Cancer enhanced" "Detected in many" "prostate cancer: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 6.5;hTCEpi: 13.6;OE19: 6.1;SiHa: 8.4;U-698: 10.4" "Region enhanced" "Detected in all" "olfactory bulb: 22.9" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.33e-1)" "unprognostic (1.62e-2)" "unprognostic (8.46e-3)" "unprognostic (5.89e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (4.99e-2)" "unprognostic (7.33e-2)" "unprognostic (6.11e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.54e-1)" "unprognostic (5.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" 3.0 2.5 2.1 1.0 2.7 0.0 5.4 3.5 2.9 3.7 5.3 2.7 0.8 3.6 21.0 3.3 4.1 6.3 3.9 2.0 2.1 5.7 99.2 3.3 0.5 2.3 2.3 11.5 5.7 15.3 2.9 0.4 2.1 14.8 3.6 4.1 23.5 2.6 0.6 15.9 1.6 2.4 2.4 0.7 2.8 4.2 2.4 0.4 6.1 1.2 1.4 2.7 3.0 2.9 0.2 0.4 0.3 1.8 0.3 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.5 6.5 4.4 0.0 0.9 1.7 0.8 1.4 0.0 0.0 2.8 0.0 1.7 1.8 4.0 0.0 0.0 0.5 13.6 0.0 1.6 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 1.5 0.5 1.1 0.1 2.9 4.0 0.7 0.0 8.4 0.0 0.2 0.4 1.5 0.0 0.0 0.2 0.9 0.0 0.1 0.0 0.0 10.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.7 3.5 2.9 2.0 2.1 2.3 2.3 2.1 2.4 2.4 2.9 3.3 16.0 1.5 3.9 0.2 4.0 8.8 2.7 2.8 1.4 4.6 6.5 5.8 10.0 4.3 3.7 2.1 0.0 0.0 1.1 5.9 2.9 12.7 4.4 1.0 3.5 0.0 5.3 3.2 0.4 0.9 4.5 1.5 3.1 0.0 2.7 1.1 62.9 0.2 0.0 2.0 4.0 10.2 2.5 0.9 20.1 6.2 0.3 3.6 8.4 0.0 8.6 0.0 1.0 7.2 0.5 2.7 9.4 0.0 7.9 0.3 5.3 7.2 1.5 0.0 1.9 2.3 0.7 0.8 2.6 15.3 0.0 0.2 6.3 2.5 8.1 CYP4F2 ENSG00000186115 "Cytochrome P450 family 4 subfamily F member 2" P78329 19 15878023-15898077 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 80.2;kidney: 40.9;liver: 166.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 139.7;Proximal enterocytes: 204.6" "Cancer enriched" "Detected in some" 9 "liver cancer: 29.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "basophil: 8.1" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.1" "Cell line enriched" "Detected in single" 4 "Hep G2: 3.8" "Low region specificity" "Detected in all" "HPA014048, HPA017265, HPA058960" Supported "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA014048: AB_1847452, HPA017265: AB_1847451, HPA058960: AB_2683862" "unprognostic (7.46e-3)" "unprognostic (3.58e-1)" "unprognostic (3.01e-1)" "unprognostic (9.39e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-2)" "unprognostic (4.55e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (8.69e-4)" "unprognostic (3.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.79e-3)" 0.0 0.0 0.1 0.1 0.1 1.1 0.2 0.1 0.3 0.1 0.5 2.2 79.9 0.0 25.8 0.2 0.0 3.3 0.0 0.2 0.1 40.9 166.7 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.1 6.6 0.9 0.0 0.0 0.1 0.0 0.8 80.2 0.0 0.3 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.0 12.3 1.9 0.1 5.8 0.0 0.0 0.1 1.8 5.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 1.4 139.7 0.0 0.0 0.0 8.9 0.0 3.8 0.0 18.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.5 204.6 37.7 0.0 0.0 0.0 0.0 0.7 0.1 0.4 0.0 0.1 0.0 0.2 0.1 5.6 0.2 CYP4F22 FLJ39501 ENSG00000171954 "Cytochrome P450 family 4 subfamily F member 22" Q6NT55 19 15508525-15552317 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;skin 1: 58.6;vagina: 22.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.8;Breast myoepithelial cells: 5.5;granulocytes: 7.0;Prostatic glandular cells: 4.0;Suprabasal keratinocytes: 3.0" "Group enriched" "Detected in many" 7 "breast cancer: 4.5;head and neck cancer: 5.7;liver cancer: 8.5;melanoma: 4.5;urothelial cancer: 13.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "intermediate monocyte: 6.1;MAIT T-cell: 4.3;non-classical monocyte: 14.1" "Group enriched" "Detected in many" 8 "monocytes: 14.1;T-cells: 4.3" "Cell line enhanced" "Detected in some" "MCF7: 1.7;T-47d: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" "HPA058960: AB_2683862" "unprognostic (2.32e-3)" "unprognostic (1.17e-2)" "unprognostic (6.81e-2)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (7.02e-2)" "unprognostic (1.30e-1)" "unprognostic (2.43e-1)" "unprognostic (3.33e-1)" "unprognostic (1.89e-2)" "unprognostic (9.33e-2)" "unprognostic (3.00e-2)" "unprognostic (2.21e-5)" "unprognostic (8.10e-2)" "unprognostic (3.16e-1)" "unprognostic (7.25e-3)" "unprognostic (2.03e-2)" 1.3 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 10.5 0.0 0.0 0.2 0.3 0.0 18.8 0.1 0.1 0.0 0.0 0.0 0.0 7.0 0.3 0.3 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 3.2 6.4 0.2 58.6 0.1 0.0 0.0 0.3 1.4 1.0 0.0 0.1 0.0 0.0 1.7 6.3 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 6.1 4.3 0.0 0.5 1.5 0.2 0.0 0.0 0.4 0.0 1.1 14.1 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 8.8 5.5 0.4 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.1 0.0 0.0 7.0 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.4 0.0 0.3 0.0 0.0 0.5 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.8 0.0 3.0 0.0 1.8 0.0 0.0 0.3 CYS1 ENSG00000205795 "Cystin 1" Q717R9 2 10056780-10080944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 124.6;pancreas: 33.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 32.9;Collecting duct cells: 51.5;Distal tubular cells: 70.5;Muller glia cells: 48.0;Proximal tubular cells: 54.1" "Cancer enhanced" "Detected in many" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "RPTEC TERT1: 111.5" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.48e-2)" "unprognostic (8.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.00e-2)" "unprognostic (2.80e-1)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (1.94e-2)" "unprognostic (9.53e-2)" "unprognostic (7.05e-2)" "unprognostic (7.03e-2)" "prognostic favorable (1.27e-5)" "unprognostic (2.19e-3)" "unprognostic (1.47e-1)" "unprognostic (8.93e-2)" "unprognostic (1.20e-2)" 3.1 1.6 6.0 1.2 5.7 0.0 1.9 5.3 7.8 8.4 15.5 11.7 2.5 7.8 3.6 3.9 6.3 9.1 6.1 5.5 5.5 124.6 1.0 6.1 1.1 6.9 6.0 12.4 33.6 1.7 7.2 0.1 5.6 4.9 1.8 2.2 2.9 7.2 1.0 1.5 3.4 5.9 6.4 2.9 3.9 1.0 5.2 0.5 5.6 2.1 2.1 3.5 6.6 5.9 0.0 0.3 0.0 0.0 0.5 2.6 0.1 0.4 1.6 0.2 0.1 0.2 0.0 0.0 0.4 4.4 0.9 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 111.5 0.0 0.0 0.5 0.4 0.3 0.0 1.3 2.0 0.2 0.0 6.0 3.2 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.7 5.3 7.8 5.5 5.5 6.9 6.0 5.6 6.4 5.2 5.9 0.9 6.4 1.1 1.0 1.0 0.5 0.1 0.6 0.0 10.3 0.5 5.5 7.3 32.9 0.0 51.5 0.0 0.0 0.2 0.0 70.5 7.0 0.1 0.3 0.9 0.6 0.0 0.0 2.9 1.1 0.6 8.8 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 0.0 3.4 1.0 0.0 2.8 0.0 48.0 0.0 3.0 0.6 0.4 0.0 4.5 0.1 0.3 0.0 54.1 0.0 1.9 0.0 0.5 3.9 0.0 1.4 0.0 0.1 0.0 0.3 0.1 0.0 0.1 DAB1 ENSG00000173406 "DAB adaptor protein 1" O75553 1 56994778-58546734 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.8;intestine: 22.3;seminal vesicle: 10.0" "Group enriched" "Detected in some" 8 "Excitatory neurons: 460.3;Inhibitory neurons: 1170.3;Oligodendrocyte precursor cells: 814.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 2.1" "Lineage enhanced" "Detected in single" "T-cells: 2.1" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 54.0;HeLa: 18.6;NTERA-2: 23.4;RT4: 32.0;WM-115: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032329, HPA052033, HPA067495" Enhanced Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "CAB032329: AB_638973, HPA052033: AB_2681703, HPA067495: AB_2685852" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (8.54e-2)" "unprognostic (2.09e-4)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (7.30e-4)" "unprognostic (3.90e-1)" "unprognostic (3.07e-2)" "unprognostic (1.47e-2)" "unprognostic (2.06e-3)" "unprognostic (1.27e-1)" "unprognostic (2.00e-3)" "unprognostic (1.78e-1)" "unprognostic (2.01e-1)" "unprognostic (1.44e-2)" "unprognostic (5.67e-2)" 2.0 1.7 4.3 0.4 5.3 0.0 0.3 16.8 8.8 1.6 0.0 0.8 15.8 0.5 0.4 0.6 1.6 0.7 1.8 10.6 5.4 0.3 7.7 0.4 0.2 2.1 3.9 1.2 0.4 0.0 0.2 0.0 2.0 3.9 0.3 5.4 0.9 10.0 0.1 0.1 22.3 0.3 2.3 0.2 1.0 0.4 5.1 0.1 0.3 0.1 0.1 1.2 0.9 1.9 0.0 0.0 10.6 0.0 0.1 0.2 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 54.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.8 0.0 0.0 0.0 0.0 2.0 0.1 23.4 0.0 0.0 6.0 0.0 0.2 0.0 32.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.6 0.1 0.0 2.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 4.3 5.3 16.8 8.8 10.6 5.4 2.1 3.9 2.0 2.3 5.1 1.9 0.7 0.0 0.0 30.0 0.1 0.0 0.1 0.1 0.0 23.7 0.1 0.3 3.2 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 8.6 8.2 0.6 0.3 0.0 0.0 460.3 0.0 0.0 0.4 4.6 12.8 0.0 0.0 0.7 5.1 0.1 21.9 1170.3 1.9 6.1 0.3 0.0 4.7 3.4 0.1 0.0 22.5 0.0 1.0 1.0 814.8 26.5 0.0 0.0 2.6 0.0 0.1 101.1 0.2 0.0 0.8 0.0 0.1 0.9 0.2 0.5 0.0 0.0 0.7 0.6 0.0 2.1 0.0 DACT2 "bA503C24.7, C6orf116, DAPPER2" ENSG00000164488 "Dishevelled binding antagonist of beta catenin 2" Q5SW24 6 168292830-168319777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.4;placenta: 12.9" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 58.2;Syncytiotrophoblasts: 216.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 14.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.2;CACO-2: 2.7;hTCEpi: 1.8;NTERA-2: 2.2;OE19: 11.2;SCLC-21H: 2.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "basal ganglia: 16.9;cerebral cortex: 21.4;hippocampal formation: 16.8" HPA030251 Enhanced Supported NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA030251: AB_10611108" "unprognostic (5.22e-6)" "unprognostic (3.13e-2)" "unprognostic (1.04e-2)" "prognostic favorable (1.07e-5)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (1.64e-2)" "unprognostic (1.08e-1)" "unprognostic (4.04e-1)" "unprognostic (1.31e-1)" "unprognostic (7.05e-3)" "unprognostic (2.48e-1)" "prognostic favorable (5.76e-5)" "unprognostic (1.51e-2)" "unprognostic (1.66e-2)" "unprognostic (2.03e-4)" "unprognostic (4.23e-2)" 2.3 3.3 3.7 0.4 19.4 0.0 0.6 2.9 6.2 1.7 1.4 1.0 0.8 2.7 0.1 1.5 1.7 0.4 5.2 2.7 2.7 3.6 5.8 1.6 0.4 4.1 3.5 0.1 2.9 0.0 0.6 12.9 4.6 7.3 0.3 5.8 6.5 0.4 0.2 5.7 0.6 0.2 2.8 0.0 0.7 1.0 4.1 1.9 0.3 0.0 0.6 1.1 1.2 3.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 11.2 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 19.4 2.9 6.2 2.7 2.7 4.1 3.5 4.6 2.8 4.1 3.0 0.0 0.0 2.0 0.0 0.0 3.1 1.9 0.8 0.0 10.7 0.1 3.0 0.6 1.5 1.3 1.8 0.0 58.2 0.0 0.1 0.0 1.3 0.0 11.8 0.5 0.7 5.3 0.0 0.1 0.2 6.1 3.4 0.0 11.0 0.0 3.3 0.0 0.3 5.3 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.1 3.6 6.5 0.0 26.3 0.0 0.0 0.1 0.3 1.2 0.0 0.0 1.1 0.0 5.7 0.0 0.9 0.0 0.5 0.1 0.0 0.3 0.0 1.4 216.3 0.2 0.0 1.9 0.1 DAPP1 BAM32 ENSG00000070190 "Dual adaptor of phosphotyrosine and 3-phosphoinositides 1" Q9UN19 4 99816827-99870190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.2;lymphoid tissue: 38.5" "Cell type enhanced" "Detected in many" "B-cells: 92.0;Langerhans cells: 188.5;monocytes: 235.5;Respiratory ciliated cells: 88.6;Urothelial cells: 221.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 61.2;RPMI-8226: 70.2;SK-BR-3: 30.6;U-698: 46.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB033822, HPA046074" Approved NA NA 56000 "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "CAB033822: AB_2245677, HPA046074: AB_2679525" "unprognostic (9.30e-2)" "unprognostic (1.36e-1)" "unprognostic (1.77e-2)" "unprognostic (9.96e-2)" "unprognostic (3.48e-1)" "unprognostic (1.14e-1)" "unprognostic (1.68e-1)" "unprognostic (9.09e-2)" "unprognostic (4.71e-1)" "unprognostic (5.13e-2)" "unprognostic (4.01e-3)" "unprognostic (2.24e-1)" "unprognostic (8.45e-5)" "unprognostic (2.88e-1)" "unprognostic (3.91e-2)" "unprognostic (9.32e-2)" "unprognostic (4.60e-2)" 1.6 1.0 0.5 22.6 0.9 15.5 3.7 0.4 0.5 6.9 0.6 3.1 2.1 8.4 1.0 29.2 5.2 11.9 0.5 0.5 0.6 0.7 1.5 6.3 34.6 1.0 1.0 0.4 0.4 0.2 0.2 6.8 1.1 2.8 3.2 0.1 8.6 0.8 0.9 13.7 6.3 13.5 0.8 16.6 6.5 0.4 0.7 10.2 0.6 1.3 38.5 14.9 12.9 1.5 22.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 22.5 23.8 0.3 0.0 0.1 12.8 0.0 25.3 0.0 61.2 0.0 24.3 0.0 0.0 0.0 9.4 1.0 0.0 11.3 0.0 7.5 0.0 0.0 1.0 1.2 21.7 0.0 0.2 0.1 6.7 0.0 0.0 0.4 0.1 0.1 70.2 4.6 16.3 0.1 0.0 0.0 30.6 0.0 0.2 0.4 10.1 0.0 0.0 0.4 0.0 0.1 8.3 3.2 46.4 0.1 6.5 0.0 25.0 70.2 71.0 2.3 62.6 2.5 90.9 11.4 4.0 75.9 98.7 12.5 4.5 138.1 17.8 57.3 32.4 25.2 65.3 0.5 0.9 0.4 0.5 0.5 0.6 1.0 1.0 1.1 0.8 0.7 1.5 0.3 3.2 3.0 0.0 92.0 61.8 30.2 51.4 16.5 0.1 10.1 5.0 0.8 2.8 43.2 9.2 0.0 2.6 13.3 8.4 0.0 6.2 0.3 37.1 0.8 1.2 1.2 9.4 0.4 3.1 14.1 1.4 14.8 9.0 8.2 0.2 0.7 0.7 25.1 0.0 0.1 1.8 22.4 32.0 188.5 0.9 0.0 86.0 12.4 5.6 235.5 0.0 7.2 0.0 0.1 18.9 17.6 0.0 60.2 24.3 0.2 0.1 88.6 0.2 0.0 0.9 4.2 0.2 0.5 40.4 70.3 3.4 17.2 0.1 2.2 221.2 DCDC2 "DCDC2A, DFNB66, KIAA1154, NPHP19, RU2" ENSG00000146038 "Doublecortin domain containing 2" Q9UHG0 6 24171755-24358059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Ciliopathy, Deafness, Disease variant, Nephronophthisis, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.1;kidney: 23.2;pancreas: 26.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 62.9;Collecting duct cells: 79.1;Distal tubular cells: 56.7;Ductal cells: 135.9;Endometrial ciliated cells: 160.3;Glandular and luminal cells: 102.4;Proximal tubular cells: 54.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 71.8;EFO-21: 48.3;Hep G2: 82.3;RPTEC TERT1: 254.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031582, HPA031583, HPA031584" Enhanced Supported "Microtubules,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Cytosol "Microtubules, Mitotic spindle, Centriolar satellite" "HPA031582: AB_10600901, HPA031583: AB_2673944, HPA031584: AB_2673945" "unprognostic (8.65e-2)" "unprognostic (2.07e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-2)" "unprognostic (1.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.09e-1)" "unprognostic (2.67e-2)" "unprognostic (5.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.99e-2)" 0.0 1.3 0.8 0.0 1.2 0.1 4.4 0.3 0.8 1.6 15.1 0.7 0.6 4.4 5.3 0.0 7.6 3.9 0.0 0.8 1.0 23.2 2.2 3.4 0.0 2.2 2.7 0.2 26.2 8.2 1.2 0.6 1.7 1.2 0.6 1.4 0.4 2.3 0.3 0.1 0.1 0.1 2.0 0.1 1.8 3.7 1.1 0.1 8.2 0.2 0.0 0.4 0.0 1.6 0.0 8.8 0.5 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 71.8 0.2 0.0 48.3 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.2 0.0 0.0 82.3 0.0 0.0 0.0 0.0 0.0 9.7 0.0 1.4 0.0 0.2 0.1 0.0 0.3 10.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 254.5 0.3 5.2 0.5 0.0 1.3 0.0 0.2 12.3 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.2 0.3 0.8 0.8 1.0 2.2 2.7 1.7 2.0 1.1 1.6 0.2 19.2 14.4 3.9 1.4 0.1 0.6 0.3 0.0 0.0 20.3 11.7 0.3 62.9 6.1 79.1 0.0 0.4 0.0 1.2 56.7 135.9 40.1 160.3 5.3 0.4 3.6 0.0 11.3 8.4 0.0 1.3 3.6 102.4 0.0 4.1 0.0 1.0 0.5 0.0 8.3 2.9 0.0 0.0 0.0 14.6 0.3 1.0 0.0 1.0 2.0 2.3 0.0 1.0 0.5 27.9 4.1 0.4 0.0 1.3 0.0 54.3 37.1 0.1 0.0 0.0 2.4 32.3 2.6 0.0 0.1 0.1 1.1 5.6 2.7 0.9 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 107.4" "Cell type enriched" "Detected in some" 23 "Melanocytes: 3552.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 272 "SK-MEL-30: 257.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.4 0.4 0.6 0.0 1.0 0.1 3.0 0.4 0.7 0.2 0.2 0.3 0.0 0.3 0.9 0.0 0.9 0.1 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.6 0.6 0.4 0.4 0.0 1.6 0.0 0.5 0.3 0.0 0.9 1.5 0.3 0.4 107.4 0.1 0.1 0.6 0.1 0.1 0.6 0.6 0.5 0.2 0.1 0.0 0.2 0.3 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 257.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.7 0.6 0.6 0.6 0.6 0.5 0.6 0.6 0.5 0.0 0.0 0.0 23.5 0.0 152.3 0.1 0.0 0.0 1.0 0.3 0.5 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.5 0.1 1.2 0.0 0.0 16.1 0.2 0.0 1.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 25.5 23.8 0.9 0.0 3552.1 1.9 0.0 3.5 0.0 6.6 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 1.0 0.5 0.8 0.0 33.4 0.0 0.9 0.1 0.0 0.0 DCX "DBCN, DC, LISX, SCLH, XLIS" ENSG00000077279 Doublecortin O43602 X 111293779-111412429 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;endometrium 1: 1.4;retina: 2.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 39.1;Inhibitory neurons: 90.2;Oligodendrocyte precursor cells: 49.8;Rod photoreceptor cells: 21.8" "Cancer enriched" "Detected in some" 5 "glioma: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 52.5;SH-SY5Y: 22.1" "Region enriched" "Detected in many" 9 "olfactory bulb: 74.0" "Region enriched" "Detected in all" 4 "olfactory bulb: 68.6" HPA036121 Enhanced Supported Approved Cytosol NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA036121: AB_2674950" "unprognostic (1.36e-2)" "unprognostic (1.99e-1)" "unprognostic (7.36e-2)" "unprognostic (4.00e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.00e-2)" "unprognostic (7.18e-2)" "unprognostic (3.24e-2)" "unprognostic (2.33e-3)" "unprognostic (3.67e-1)" "unprognostic (4.90e-4)" "unprognostic (5.02e-3)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" 0.1 0.2 2.1 0.0 2.4 0.0 1.3 0.0 2.5 0.1 0.0 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.0 1.4 2.7 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.3 0.0 0.8 0.0 0.0 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 52.5 22.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 0.0 2.5 1.4 2.7 0.2 1.3 0.8 0.0 2.4 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.5 1.6 2.2 0.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 39.1 0.0 0.2 6.8 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 90.2 0.2 0.0 0.0 0.4 0.5 0.0 0.0 1.8 1.9 0.0 1.6 0.0 49.8 2.3 0.1 0.0 1.5 0.0 0.0 0.0 0.1 0.0 21.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.2 0.0 0.0 DDB2 "DDBB, FLJ34321, UV-DDB2, XPE" ENSG00000134574 "Damage specific DNA binding protein 2" Q92466 11 47214465-47239217 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;monocytes: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025912, HPA058406" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cell Junctions" "CAB025912: , HPA058406: AB_2683708" "prognostic favorable (7.29e-4)" "prognostic favorable (1.58e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.20e-4)" "unprognostic (4.29e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-2)" "unprognostic (6.18e-2)" "unprognostic (2.25e-1)" "unprognostic (3.58e-3)" "unprognostic (3.53e-1)" "unprognostic (1.94e-1)" "unprognostic (4.57e-3)" "unprognostic (1.21e-2)" "unprognostic (4.25e-2)" "unprognostic (9.82e-3)" "unprognostic (1.07e-1)" 13.2 22.5 2.6 8.2 3.2 11.6 13.5 3.4 3.6 12.5 3.4 12.8 7.6 12.7 11.7 24.8 17.6 12.5 6.8 2.5 2.4 4.4 27.0 12.2 14.7 3.4 2.7 11.6 14.4 4.8 4.7 6.8 3.5 9.7 14.9 2.3 14.4 11.7 6.2 46.7 10.2 13.9 2.7 11.3 9.5 4.5 3.2 23.5 5.5 6.9 17.0 11.2 14.1 3.6 23.7 62.3 25.9 19.3 16.6 32.7 29.9 26.0 58.8 32.0 37.1 10.1 14.1 56.6 5.3 23.2 23.6 40.8 14.6 51.8 15.7 14.5 27.5 13.3 55.7 46.7 15.8 15.9 34.4 43.4 58.0 15.9 35.2 10.2 94.2 14.7 3.5 27.0 52.7 44.4 60.4 7.7 8.4 31.1 22.3 30.3 5.6 30.6 13.5 22.7 13.2 16.7 31.2 8.7 8.1 30.8 56.1 5.5 41.2 96.8 44.1 21.3 12.6 27.6 22.4 12.5 37.0 20.2 35.9 9.8 12.8 20.2 19.3 18.4 18.8 18.3 20.1 18.8 10.4 14.5 14.8 15.7 3.7 14.1 15.8 0.3 47.7 15.9 2.6 3.2 3.4 3.6 2.5 2.4 3.4 2.7 3.5 2.7 3.2 3.6 13.8 16.0 22.2 7.8 25.1 38.9 39.7 28.1 75.1 5.0 18.0 25.8 7.8 11.5 16.3 5.5 10.4 3.6 21.3 11.1 9.8 12.5 1.5 5.2 8.1 19.5 7.7 19.1 6.6 13.8 9.0 16.0 18.3 9.5 22.8 31.2 15.0 16.6 17.5 1.7 1.4 12.6 16.2 17.5 12.8 2.1 19.0 16.8 19.6 24.4 135.5 9.6 35.0 1.0 10.6 19.9 9.8 10.5 34.1 8.9 15.7 7.7 13.9 12.8 0.0 12.1 14.0 3.1 8.6 34.5 30.3 1.5 34.3 25.4 16.5 26.5 DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 476.0;breast: 133.6;liver: 331.8;skin 1: 151.5" "Cell type enhanced" "Detected in many" "Early spermatids: 259.3;Hepatocytes: 116.4;Late spermatids: 64.1;Spermatocytes: 53.9;Spermatogonia: 53.5" "Cancer enhanced" "Detected in many" "liver cancer: 19.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 137.7;neutrophil: 348.6" "Lineage enriched" "Detected in many" 16 "granulocytes: 348.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.4;HDLM-2: 62.5;Hep G2: 64.9;OE19: 124.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 22.0" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA013351: AB_1847630" "unprognostic (2.28e-1)" "unprognostic (3.69e-1)" "unprognostic (9.38e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.63e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "unprognostic (7.59e-2)" "unprognostic (4.46e-1)" "unprognostic (4.12e-3)" "unprognostic (2.87e-1)" "unprognostic (2.99e-1)" "unprognostic (1.49e-7)" "unprognostic (2.03e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (5.60e-2)" 476.0 5.1 5.8 19.4 11.7 7.2 133.6 2.9 6.1 2.6 5.3 9.0 14.5 1.2 1.8 24.1 2.1 5.8 11.7 5.7 6.4 3.4 331.8 5.6 4.0 3.7 3.9 1.8 4.6 2.1 1.6 1.5 5.5 2.2 4.9 0.6 10.5 1.6 4.1 151.5 16.5 2.8 3.4 15.0 12.8 38.1 6.9 4.3 8.8 5.6 18.2 21.3 12.6 5.1 13.3 6.4 0.4 11.2 80.4 6.4 1.0 1.3 1.7 1.6 1.0 46.6 13.5 21.1 16.8 0.3 11.9 0.5 1.8 6.5 4.4 62.5 1.2 1.5 4.0 64.9 0.9 7.4 7.2 26.8 33.6 7.3 10.6 4.4 1.2 20.9 1.2 27.6 0.7 8.5 5.1 16.7 3.6 124.0 31.5 0.0 0.1 24.8 1.2 35.8 22.6 1.4 12.3 1.9 2.9 2.7 4.4 26.6 1.6 14.1 7.0 0.3 9.1 16.3 40.0 28.8 10.2 23.7 25.3 19.4 22.1 137.7 0.0 4.4 0.4 7.4 0.4 0.0 6.1 7.6 0.1 0.2 348.6 0.0 5.0 1.8 0.0 5.7 5.8 11.7 2.9 6.1 5.7 6.4 3.7 3.9 5.5 3.4 6.9 5.1 3.2 6.4 5.4 0.3 5.0 1.1 0.9 3.0 0.6 0.9 5.2 7.0 3.5 0.0 2.7 0.0 2.1 0.5 0.3 0.6 0.0 1.7 259.3 3.3 0.2 0.5 1.2 2.7 2.9 0.5 0.1 0.7 10.7 0.2 0.0 2.1 2.9 116.4 2.2 1.7 1.3 4.8 0.0 4.1 13.1 64.1 2.1 4.2 1.8 0.0 4.0 0.4 0.0 0.0 1.0 3.7 2.2 0.7 0.9 2.8 1.2 2.2 3.4 0.0 6.6 0.6 1.0 53.9 53.5 0.3 8.0 0.8 0.5 0.2 3.0 15.7 DGKE "DAGK6, DGK" ENSG00000153933 "Diacylglycerol kinase epsilon" P52429 17 56834107-56869567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 34.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 181.1;Cone photoreceptor cells: 189.7;Inhibitory neurons: 90.0;Rod photoreceptor cells: 165.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 84.8;MOLT-4: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017167 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA017167: AB_1847638" "unprognostic (1.19e-2)" "unprognostic (2.11e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.92e-5)" "unprognostic (4.20e-2)" "unprognostic (4.87e-2)" "unprognostic (3.37e-1)" "unprognostic (4.27e-2)" "unprognostic (1.19e-3)" "unprognostic (4.75e-2)" "unprognostic (6.07e-3)" "unprognostic (2.68e-1)" "unprognostic (2.55e-2)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-1)" "unprognostic (3.69e-3)" 4.1 2.2 5.4 4.5 6.9 3.1 3.0 9.4 7.4 4.9 7.7 4.9 2.6 6.5 4.2 2.6 4.8 4.6 2.9 5.8 8.1 2.6 2.8 5.2 5.0 3.3 4.7 3.5 3.9 4.1 6.2 2.7 3.4 4.1 3.3 34.5 2.5 3.3 1.2 1.9 4.4 4.3 2.7 6.9 3.7 6.5 6.9 9.8 4.0 2.2 4.3 3.8 4.2 5.8 3.5 3.3 3.0 0.3 0.6 1.0 1.4 5.8 4.7 3.9 4.5 7.7 4.2 5.1 7.0 3.1 1.9 4.2 7.2 3.2 7.8 16.5 9.5 6.6 8.9 5.1 3.3 12.7 8.9 1.9 4.0 4.1 8.0 3.6 5.4 14.7 5.5 84.8 4.8 5.1 30.3 7.1 2.3 4.6 10.0 9.4 12.4 12.2 3.9 7.6 4.7 3.2 4.7 2.5 0.2 1.9 5.3 6.0 5.0 1.1 5.4 1.7 0.9 11.3 25.3 3.4 3.3 7.3 0.3 0.1 0.2 0.0 1.0 0.1 0.7 0.9 0.6 0.7 0.2 0.3 0.7 0.9 0.3 0.7 0.2 0.8 1.7 0.3 5.4 6.9 9.4 7.4 5.8 8.1 3.3 4.7 3.4 2.7 6.9 5.8 51.2 3.2 6.0 10.4 11.3 8.9 13.5 3.1 21.6 181.1 5.0 6.3 6.3 10.0 4.0 16.5 189.7 6.6 16.3 5.6 0.0 7.4 18.3 9.0 9.9 30.6 11.3 2.1 66.0 4.7 3.0 6.9 9.7 19.3 0.0 13.1 29.3 4.0 2.2 8.4 90.0 7.7 8.2 5.0 9.3 9.2 4.4 7.4 3.6 32.8 6.3 18.6 14.4 32.6 14.4 6.0 6.4 5.3 15.1 21.3 1.9 0.1 2.8 165.4 6.6 11.8 10.7 28.5 20.7 9.7 6.7 3.4 18.9 5.7 5.8 13.4 DIAPH3 "AN, AUNA1, DRF3, FLJ34705, NSDAN" ENSG00000139734 "Diaphanous related formin 3" Q9NSV4 13 59665583-60163928 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;testis: 18.9" "Cell type enriched" "Detected in many" 5 "Early spermatids: 414.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032151 Supported "Plasma membrane,Microtubules" NA Yes "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Microtubules" "HPA032151: AB_2674181" "unprognostic (3.78e-2)" "unprognostic (1.28e-2)" "prognostic favorable (9.04e-4)" "prognostic unfavorable (4.18e-4)" "unprognostic (2.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.27e-4)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.74e-2)" "unprognostic (2.19e-1)" "unprognostic (5.22e-5)" "unprognostic (3.59e-3)" "unprognostic (5.31e-5)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-3)" 0.4 0.1 0.1 1.7 0.2 7.1 0.8 0.3 0.3 0.3 0.2 1.9 1.9 0.6 0.0 2.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 1.2 2.4 0.2 0.3 0.1 0.2 0.1 0.0 3.5 0.2 0.1 2.1 0.0 0.5 0.0 0.0 1.3 1.6 2.6 0.1 0.5 1.6 18.9 0.3 5.4 0.1 0.0 2.4 0.6 0.7 0.2 47.7 15.6 15.8 9.1 2.7 7.1 26.9 65.0 28.7 64.2 55.6 41.7 31.4 15.9 5.2 33.4 16.7 31.7 26.0 25.5 96.9 18.0 17.9 22.7 37.6 9.5 4.1 31.2 17.4 2.8 0.6 39.2 26.3 16.3 29.2 14.0 17.8 21.9 61.8 6.9 28.0 10.2 14.7 22.5 8.9 18.8 38.9 12.9 19.9 9.6 8.3 14.3 33.2 22.8 9.5 33.8 16.7 16.8 29.3 40.5 25.9 13.7 54.5 14.7 17.1 24.4 10.9 15.2 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.2 0.6 54.5 3.4 39.8 1.9 3.7 0.8 2.1 2.8 0.0 3.9 1.5 1.0 2.8 1.8 0.0 0.0 21.1 1.1 3.8 5.9 1.3 414.4 2.5 3.5 2.1 0.0 26.7 5.6 4.0 30.7 5.8 9.7 9.3 0.0 78.8 1.8 0.4 6.1 0.0 3.3 2.6 2.0 1.0 1.2 56.0 0.6 1.5 0.0 5.6 0.1 3.5 2.1 19.1 1.8 1.5 0.2 0.0 18.9 0.4 1.1 5.4 0.2 0.0 0.0 0.0 7.9 39.2 17.8 11.6 1.1 7.3 2.2 2.8 5.6 1.5 DKK1 "DKK-1, SK" ENSG00000107984 "Dickkopf WNT signaling pathway inhibitor 1" O94907 10 52314281-52318042 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.0;placenta: 48.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 486.2;Endometrial stromal cells: 337.6;Pancreatic endocrine cells: 194.6;Prostatic glandular cells: 992.9;Urothelial cells: 320.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1141.1;BJ hTERT+: 620.0;CACO-2: 1011.3;fHDF/TERT166: 1590.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.65e-2)" "unprognostic (4.21e-2)" "unprognostic (7.09e-2)" "unprognostic (7.99e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.35e-8)" "unprognostic (7.93e-2)" "prognostic unfavorable (7.80e-6)" "unprognostic (1.54e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.81e-1)" "unprognostic (1.68e-1)" "unprognostic (7.47e-3)" "unprognostic (4.05e-1)" "unprognostic (1.19e-1)" "unprognostic (2.06e-2)" 22.0 0.3 0.6 0.3 0.8 0.0 5.6 1.1 0.9 34.0 0.4 0.3 0.1 1.8 0.0 7.9 0.4 3.9 0.7 0.5 1.5 0.6 0.2 1.2 0.4 0.6 1.6 1.0 0.2 0.1 0.1 48.9 0.8 4.8 0.1 7.0 2.3 1.9 0.3 16.5 0.2 0.2 0.7 0.8 1.2 0.2 1.7 0.0 0.3 0.0 0.5 21.9 10.6 0.6 315.3 215.8 0.1 32.4 149.6 30.4 0.1 1141.1 620.0 383.8 202.5 1011.3 64.2 0.0 1.6 1590.5 93.5 245.1 0.3 130.7 361.3 0.1 0.7 0.0 4.4 26.2 31.8 0.0 0.1 30.3 16.0 83.0 488.3 19.8 35.8 0.0 0.0 0.1 255.8 135.7 0.0 0.1 0.2 13.7 543.9 0.2 34.8 0.0 148.6 25.6 0.2 342.4 102.8 1.1 17.7 0.4 1.1 0.9 78.9 0.2 0.2 338.5 211.9 0.1 0.3 0.1 4.6 0.1 37.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.1 0.9 0.5 1.5 0.6 1.6 0.8 0.7 1.7 0.6 1.9 25.6 0.0 0.0 1.0 5.4 486.2 28.5 0.0 0.2 0.8 6.9 1.1 0.0 15.2 0.0 0.0 4.6 0.0 0.9 0.0 10.7 1.2 11.0 337.6 8.5 0.0 0.0 1.2 4.1 4.0 91.5 2.6 8.1 4.5 0.0 1.1 0.0 9.3 0.0 2.2 2.4 6.1 0.0 1.6 0.6 0.0 4.9 0.0 1.0 0.0 6.1 0.0 1.5 0.2 194.6 5.0 0.0 1.3 992.9 0.4 0.0 9.8 0.4 0.0 0.0 10.6 0.4 2.2 1.4 3.1 8.3 2.8 0.0 1.0 320.0 DLG2 "chapsyn-110, PPP1R58, PSD-93, PSD93" ENSG00000150672 "Discs large MAGUK scaffold protein 2" Q15700 11 83455012-85627922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3292.3;Inhibitory neurons: 2602.7;Oligodendrocyte precursor cells: 2331.8;Oligodendrocytes: 4213.8" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 8.2;SH-SY5Y: 8.1;T-47d: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021307, HPA023896, CAB072341" Enhanced Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "CAB072341: , HPA021307: AB_1846625, HPA023896: AB_2671353" "unprognostic (2.61e-3)" "unprognostic (2.81e-2)" "unprognostic (4.05e-2)" "unprognostic (9.03e-2)" "unprognostic (3.25e-1)" "unprognostic (1.09e-1)" "unprognostic (9.44e-3)" "unprognostic (7.78e-2)" "unprognostic (4.32e-1)" "unprognostic (4.61e-2)" "unprognostic (9.28e-3)" "unprognostic (4.84e-1)" "unprognostic (7.66e-6)" "unprognostic (2.92e-2)" "unprognostic (2.41e-1)" "unprognostic (6.52e-2)" "unprognostic (8.89e-2)" 1.6 11.0 29.5 1.1 48.7 0.3 2.1 3.6 55.8 1.8 0.0 2.3 1.2 2.9 4.1 7.5 5.7 2.1 3.0 64.4 18.1 3.6 2.8 1.7 1.1 13.5 8.2 5.7 3.3 7.3 10.0 2.4 10.3 4.0 1.4 25.4 3.1 4.6 0.8 20.2 1.2 2.2 11.9 2.5 1.5 8.1 10.5 7.3 15.5 0.7 2.9 1.7 2.6 88.4 0.6 0.3 0.9 0.5 0.6 0.7 8.2 0.2 0.5 0.4 0.3 7.4 1.1 1.3 1.3 0.4 0.5 0.8 2.3 0.7 0.4 0.8 0.9 1.3 5.0 0.2 0.1 0.4 1.1 0.5 0.5 1.0 1.0 0.4 0.5 1.9 1.2 3.5 0.7 0.9 0.6 1.3 6.0 0.8 1.3 1.4 2.0 0.9 0.4 0.3 5.9 8.1 0.8 5.1 0.4 7.2 21.2 0.0 0.3 2.2 1.8 2.1 0.3 0.8 2.9 5.6 0.8 0.7 0.2 0.0 0.0 0.2 0.1 0.0 0.5 0.1 0.1 0.2 0.0 0.6 0.6 0.2 0.0 0.0 0.1 0.5 0.0 0.0 29.5 48.7 3.6 55.8 64.4 18.1 13.5 8.2 10.3 11.9 10.5 88.4 7.0 3.2 10.4 742.8 1.3 3.3 3.6 0.3 9.1 298.1 4.4 5.2 8.3 2.8 1.8 7.3 275.2 7.9 1.8 1.5 9.8 0.7 21.5 1.3 2.7 3.6 4.2 0.0 3292.3 0.4 0.5 7.4 1.1 2.4 0.0 1.6 2.2 4.6 4.0 23.5 2602.7 1.1 0.0 0.3 0.0 16.4 7.8 0.8 1.8 487.2 0.6 11.0 0.0 2331.8 4213.8 0.4 0.1 6.4 0.1 2.0 0.6 2.7 0.9 48.2 6.6 7.1 4.1 11.3 3.2 6.2 8.5 2.1 1.7 12.1 0.9 0.8 DLG4 "PSD-95, PSD95, SAP-90, SAP90" ENSG00000132535 "Discs large MAGUK scaffold protein 4" P78352 17 7187187-7219841 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 112.4;pituitary gland: 62.8;retina: 223.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.8;Cone photoreceptor cells: 102.2;Rod photoreceptor cells: 62.6" "Cancer enhanced" "Detected in all" "glioma: 13.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 40.0;hTERT-RPE1: 45.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001999, CAB002000, HPA010122, HPA071006" Enhanced "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB001999: , CAB002000: , HPA010122: AB_1855169, HPA071006: " "unprognostic (7.08e-2)" "unprognostic (1.06e-2)" "unprognostic (3.50e-3)" "unprognostic (2.48e-2)" "unprognostic (3.23e-2)" "unprognostic (1.80e-1)" "unprognostic (7.18e-3)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (2.72e-2)" "prognostic favorable (8.82e-6)" "unprognostic (3.45e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.12e-2)" "unprognostic (2.83e-2)" "unprognostic (3.68e-2)" "unprognostic (4.77e-3)" 13.1 19.1 41.9 9.3 49.6 3.6 10.0 32.1 112.4 23.5 0.0 18.5 4.9 23.1 6.9 6.3 20.7 10.8 19.6 86.3 17.5 10.3 7.1 14.7 4.4 7.2 0.4 30.3 6.3 7.2 62.8 8.9 5.6 16.6 3.5 223.2 7.2 12.8 6.1 4.7 8.4 11.1 0.0 13.9 10.3 18.9 7.7 8.7 11.0 2.8 2.9 13.3 16.4 36.2 0.5 15.2 29.4 9.1 8.4 14.6 1.5 14.1 12.5 10.8 11.3 0.7 4.0 2.4 6.4 12.1 1.6 1.8 1.1 6.7 3.3 17.6 6.0 9.4 35.1 1.4 8.0 0.3 40.0 17.5 0.9 7.7 11.0 45.5 11.5 10.1 3.1 10.1 15.2 1.0 9.3 5.1 3.8 0.8 1.6 10.5 1.6 1.0 6.6 0.3 12.4 10.5 0.4 0.8 2.6 7.0 6.5 7.2 16.4 30.6 12.6 7.4 7.8 1.5 0.9 2.1 19.3 6.9 8.5 0.4 0.2 0.1 0.2 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.4 0.0 0.1 41.9 49.6 32.1 112.4 86.3 17.5 7.2 0.4 5.6 0.0 7.7 36.2 3.4 0.0 1.5 14.0 1.5 2.7 2.2 1.8 6.2 41.8 4.8 3.7 3.2 1.5 2.2 3.7 102.2 0.6 3.3 0.4 0.0 0.9 1.8 2.4 9.5 7.0 15.0 0.8 22.8 0.2 0.4 5.5 2.0 3.2 7.0 3.4 10.0 2.2 3.9 20.2 17.5 0.8 4.1 11.0 10.3 1.3 7.2 7.8 3.6 8.4 5.5 11.1 0.0 4.5 4.2 0.2 0.1 10.1 0.2 1.7 1.3 0.3 3.0 62.6 0.0 1.4 4.5 6.5 2.9 3.2 1.8 0.5 1.1 6.8 0.5 1.1 DLX2 TES-1 ENSG00000115844 "Distal-less homeobox 2" Q07687 2 172099438-172102900 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 3.0" "Cell type enhanced" "Detected in some" "dendritic cells: 6.5;Early spermatids: 6.9;Gastric mucus-secreting cells: 5.6;Inhibitory neurons: 10.0;Melanocytes: 5.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "hypothalamus: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "AN3-CA: 79.7;HEK 293: 50.8" "Region enhanced" "Detected in many" "olfactory bulb: 29.4" "Region enriched" "Detected in many" 5 "olfactory bulb: 23.2" HPA056965 Approved "Nuclear speckles" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA056965: AB_2683291" "unprognostic (8.12e-2)" "unprognostic (3.56e-1)" "unprognostic (2.48e-2)" "unprognostic (1.28e-2)" "unprognostic (4.07e-1)" "unprognostic (2.13e-1)" "unprognostic (8.60e-3)" "unprognostic (3.03e-2)" "unprognostic (2.41e-1)" "unprognostic (8.74e-2)" "unprognostic (3.53e-2)" "unprognostic (3.01e-1)" "unprognostic (6.69e-10)" "unprognostic (9.38e-2)" "unprognostic (2.47e-1)" "unprognostic (2.41e-1)" "unprognostic (7.95e-3)" 0.0 0.3 1.4 0.0 1.1 0.1 0.2 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 79.7 0.5 0.3 2.2 4.3 1.0 0.7 0.2 0.5 0.2 0.0 2.4 2.0 3.8 4.1 2.6 0.3 0.2 0.1 50.8 1.3 8.8 2.0 0.2 0.4 0.3 0.0 3.7 0.1 0.5 0.3 0.0 2.0 0.6 0.0 0.5 0.2 0.1 0.6 0.1 0.0 1.1 0.0 0.4 0.0 0.1 0.1 2.8 0.0 2.1 1.2 5.0 1.3 0.6 0.4 0.4 5.5 0.0 3.0 0.5 0.1 0.1 0.5 4.7 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.1 0.0 0.9 0.4 3.0 0.0 0.0 0.0 0.0 0.5 0.1 1.4 0.0 0.0 0.0 1.3 1.8 0.2 0.9 0.6 0.0 3.1 3.6 0.4 0.0 0.2 0.0 0.0 0.4 6.5 1.0 0.0 0.0 6.9 1.6 0.3 0.5 0.0 0.0 0.1 0.0 0.3 0.2 5.6 1.1 0.0 0.0 0.0 0.0 0.5 0.0 10.0 1.1 0.0 0.0 0.3 0.1 0.0 1.8 5.4 1.0 0.0 0.2 0.0 0.0 0.1 0.0 1.2 0.0 0.4 0.1 1.3 0.0 0.1 0.0 0.0 0.3 1.5 0.9 0.7 1.6 0.0 0.4 1.5 0.2 0.6 0.0 DLX5 ENSG00000105880 "Distal-less homeobox 5" P56178 7 97020396-97024950 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 14.1;placenta: 11.7;skin 1: 21.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 168.9;Endometrial ciliated cells: 217.8;Extravillous trophoblasts: 245.2;Glandular and luminal cells: 191.2;Syncytiotrophoblasts: 314.8" "Cancer enriched" "Detected in many" 11 "endometrial cancer: 81.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 53.7;HAP1: 27.2;SuSa: 13.4" "Group enriched" "Detected in many" 4 "basal ganglia: 13.5;olfactory bulb: 29.8" "Group enriched" "Detected in many" 4 "basal ganglia: 7.5;olfactory bulb: 18.0" HPA005670 Approved Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA005670: AB_1078681" "unprognostic (3.99e-1)" "unprognostic (1.05e-1)" "unprognostic (2.96e-2)" "unprognostic (1.31e-3)" "unprognostic (1.76e-1)" "unprognostic (2.86e-2)" "unprognostic (6.14e-2)" "unprognostic (2.46e-2)" "unprognostic (5.89e-2)" "unprognostic (6.20e-2)" "unprognostic (1.52e-1)" "unprognostic (1.01e-2)" "unprognostic (7.43e-8)" "unprognostic (1.39e-2)" "unprognostic (3.73e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" 1.5 0.3 2.1 0.2 3.9 0.0 0.9 0.2 3.4 7.6 0.4 0.6 0.3 14.1 1.0 1.9 1.3 0.4 0.5 1.5 4.5 0.5 0.0 0.2 1.7 0.2 0.3 1.6 0.0 0.2 0.8 11.7 0.3 1.7 0.0 0.0 3.3 2.8 0.3 21.2 0.1 0.9 0.3 0.1 0.1 0.9 1.5 1.8 1.5 0.0 2.1 0.7 3.0 1.3 0.0 0.0 0.0 8.2 0.0 0.0 53.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 6.2 27.2 0.0 0.0 0.0 4.6 0.0 0.6 0.4 0.0 0.0 0.0 0.1 8.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.0 3.6 1.5 2.1 0.2 0.0 0.0 13.4 0.0 0.0 0.0 1.7 0.3 0.4 0.0 0.0 0.0 0.0 3.2 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 3.9 0.2 3.4 1.5 4.5 0.2 0.3 0.3 0.3 1.5 1.3 1.4 0.0 0.0 0.0 0.0 9.8 1.1 1.7 0.6 0.0 0.3 0.6 0.2 0.0 0.1 0.0 0.0 168.9 0.0 0.0 0.0 0.0 0.2 217.8 13.3 2.9 0.0 0.0 0.1 0.0 245.2 1.5 0.0 191.2 0.0 1.6 0.0 0.0 16.9 0.0 12.8 0.0 0.0 0.0 1.1 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.1 59.2 0.2 8.0 4.2 11.6 7.9 20.6 314.8 1.6 0.1 0.0 1.6 DLX6 ENSG00000006377 "Distal-less homeobox 6" P56179 7 97005553-97011040 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.3;testis: 5.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 32.9;Early spermatids: 22.6;Endometrial ciliated cells: 37.3;Extravillous trophoblasts: 70.4;Glandular and luminal cells: 27.5;Syncytiotrophoblasts: 17.4" "Cancer enriched" "Detected in many" 8 "endometrial cancer: 12.5" "Region enhanced" "Detected in many" "basal ganglia: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 33.4;HAP1: 15.3;SH-SY5Y: 11.0;SuSa: 19.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory bulb: 27.0" "HPA030608, HPA061460" Uncertain Approved "Nuclear bodies" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear bodies" "HPA030608: AB_10600867, HPA061460: AB_2684529" "unprognostic (7.50e-2)" "unprognostic (1.91e-1)" "unprognostic (5.19e-2)" "unprognostic (8.06e-2)" "unprognostic (8.16e-2)" "unprognostic (3.05e-1)" "unprognostic (4.32e-2)" "unprognostic (2.51e-1)" "unprognostic (2.86e-1)" "unprognostic (6.56e-2)" "unprognostic (8.09e-2)" "unprognostic (1.12e-7)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (5.58e-2)" "unprognostic (8.12e-2)" 0.4 0.0 2.1 0.0 7.3 0.3 0.1 0.0 4.3 2.0 0.0 0.2 0.0 2.5 0.8 0.0 0.4 0.0 0.1 0.8 4.7 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 3.0 0.0 0.3 0.0 0.0 1.1 0.9 0.1 1.5 0.0 0.2 0.0 0.1 0.0 5.5 1.2 0.3 0.4 0.1 0.2 0.3 0.2 0.4 0.0 0.0 0.0 10.1 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 6.1 0.0 0.0 1.9 15.3 0.0 0.0 0.0 3.9 0.0 5.9 7.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 2.6 1.6 0.0 0.0 0.0 0.0 2.2 7.3 11.0 1.0 0.0 0.3 19.3 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.9 1.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 7.3 0.0 4.3 0.8 4.7 0.0 0.0 0.0 0.0 1.2 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 32.9 0.1 0.0 0.0 0.0 22.6 37.3 2.2 0.2 0.0 0.0 0.0 0.0 70.4 0.2 0.0 27.5 0.0 0.0 0.0 0.0 3.3 0.0 8.0 0.0 0.0 0.0 0.0 3.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.8 6.8 10.2 0.0 0.0 17.4 0.3 0.0 0.0 0.1 DMTN "DMT, EPB49" ENSG00000158856 "Dematin actin binding protein" Q08495 8 22048995-22082527 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 192.5" "Cell type enriched" "Detected in many" 5 "Erythroid cells: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 3.8;memory CD8 T-cell: 1.6;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.5;neutrophil: 1.2;T-reg: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;T-cells: 3.8" "Cell line enhanced" "Detected in many" "A549: 68.9;HEL: 225.9;Hep G2: 63.9;HMC-1: 65.6;OE19: 67.3;RPTEC TERT1: 87.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024290, HPA058487" Uncertain NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA024290: AB_1847601, HPA058487: " "unprognostic (6.74e-2)" "unprognostic (1.51e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-3)" "prognostic unfavorable (7.92e-5)" "unprognostic (2.88e-1)" "unprognostic (3.85e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-2)" "unprognostic (2.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.97e-1)" "prognostic favorable (3.85e-9)" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (1.86e-1)" "unprognostic (8.07e-2)" 35.7 29.8 104.2 6.1 134.6 136.6 21.8 0.0 192.5 13.5 0.0 33.1 9.2 15.3 14.4 18.9 30.4 13.5 71.5 142.1 36.9 67.5 28.2 20.1 3.4 27.0 14.0 3.4 29.6 54.9 109.6 7.4 27.1 25.0 15.2 23.0 22.9 20.4 66.4 24.3 14.0 14.0 0.0 19.3 23.8 11.7 32.4 3.0 39.1 41.4 3.7 12.9 12.4 90.5 44.1 68.9 0.5 1.4 1.1 0.3 5.4 4.6 4.3 14.5 4.3 29.9 26.7 0.4 43.8 0.8 0.9 14.8 2.1 2.7 6.5 0.4 13.0 225.9 5.3 63.9 1.3 0.1 65.6 0.7 29.3 0.2 0.3 8.5 14.7 2.0 21.7 2.2 0.1 18.9 5.7 0.5 1.8 67.3 6.1 0.0 0.6 3.1 87.2 12.3 15.6 21.8 7.3 0.9 3.2 3.5 11.2 2.2 26.1 0.0 22.0 0.3 24.0 0.1 0.2 0.7 0.3 0.2 15.4 0.0 0.1 0.2 1.7 0.0 1.7 0.0 3.8 1.6 0.1 0.0 1.5 1.5 1.2 0.0 0.0 0.3 3.3 9.3 104.2 134.6 0.0 192.5 142.1 36.9 27.0 14.0 27.1 0.0 32.4 90.5 9.3 3.2 10.7 10.7 1.5 2.3 4.0 3.9 1.2 34.6 9.9 5.7 37.8 0.0 5.1 7.3 12.5 0.1 2.7 15.3 19.6 11.4 12.7 11.2 1.7 10.2 20.5 248.6 45.7 11.4 1.7 2.4 7.7 12.7 0.0 4.1 3.9 15.8 0.5 28.6 29.7 8.7 0.0 1.0 1.6 7.7 0.3 44.5 14.2 5.6 1.3 2.6 0.0 1.5 4.3 18.2 10.0 2.6 1.4 3.7 1.8 29.6 9.3 7.3 0.0 1.4 5.7 1.4 2.4 3.8 5.7 0.1 6.4 0.3 13.3 4.8 DNAH2 "DNHD3, FLJ46675, KIAA1503" ENSG00000183914 "Dynein axonemal heavy chain 2" Q9P225 17 7717354-7833744 "Predicted intracellular proteins, Predicted membrane proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 13.1;parathyroid gland: 10.5;retina: 21.1" "Group enriched" "Detected in many" 4 "Respiratory ciliated cells: 43.0;Rod photoreceptor cells: 123.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.6;CACO-2: 4.0;CAPAN-2: 2.4;OE19: 1.8;SCLC-21H: 2.3;SiHa: 2.3" "Low region specificity" "Detected in some" HPA067103 Enhanced Approved Microtubules NA NA "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Microtubules "HPA067103: AB_2685778" "unprognostic (2.03e-2)" "unprognostic (1.79e-2)" "unprognostic (2.23e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" "unprognostic (2.51e-1)" "unprognostic (1.35e-1)" "unprognostic (7.50e-3)" "unprognostic (1.29e-2)" "unprognostic (8.28e-2)" "unprognostic (2.51e-3)" "unprognostic (1.74e-1)" "unprognostic (2.06e-2)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (8.74e-3)" "unprognostic (4.60e-2)" 0.4 0.1 1.5 0.1 2.4 0.5 0.5 1.0 1.1 1.2 7.1 0.2 0.2 0.5 1.6 0.1 13.1 0.4 0.1 1.8 1.1 0.1 0.4 1.9 0.1 5.6 6.8 2.5 0.5 10.5 0.4 1.7 2.8 0.3 0.2 21.1 0.1 0.0 0.1 0.2 0.1 0.2 3.5 0.2 0.2 6.5 1.1 0.3 0.3 0.0 0.1 0.2 0.1 1.8 2.6 0.1 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 4.0 2.4 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.1 0.0 0.3 0.1 0.6 0.1 0.1 0.2 0.0 0.4 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.5 0.1 0.2 0.2 1.8 0.8 0.1 0.2 0.0 0.0 0.7 2.3 0.1 2.3 0.0 1.2 0.2 0.2 0.1 0.1 0.2 0.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.6 0.1 0.0 0.1 0.0 0.0 1.5 2.4 1.0 1.1 1.8 1.1 5.6 6.8 2.8 3.5 1.1 1.8 1.1 0.0 1.1 1.3 0.7 0.3 1.0 1.7 0.0 2.7 0.6 1.0 1.9 0.0 3.6 0.0 2.1 0.0 0.0 0.0 0.0 0.4 6.2 20.2 0.6 1.2 6.7 0.0 6.1 0.0 0.0 0.8 0.0 0.8 0.0 2.3 0.4 0.1 0.1 1.7 4.9 0.5 8.2 0.3 0.7 2.3 0.3 0.2 0.0 1.0 0.0 4.6 0.0 3.0 2.1 0.1 1.1 0.0 0.0 0.7 0.0 0.4 43.0 123.9 0.0 1.0 1.0 9.6 2.6 0.0 0.1 0.0 0.2 0.5 0.2 0.9 DNAH3 "DKFZp434N074, DLP3, Dnahc3b, Hsadhc3" ENSG00000158486 "Dynein axonemal heavy chain 3" Q8TD57 16 20933111-21159441 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;fallopian tube: 5.1;testis: 4.3" "Cell type enhanced" "Detected in some" "Early spermatids: 42.7;Endometrial ciliated cells: 31.0;Late spermatids: 17.1;Respiratory ciliated cells: 77.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062493 Approved "Nuclear membrane,Intermediate filaments" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear membrane" "Intermediate filaments" "HPA062493: " "unprognostic (1.68e-1)" "unprognostic (9.84e-2)" "unprognostic (1.32e-1)" "unprognostic (2.11e-3)" "unprognostic (1.25e-2)" "unprognostic (5.23e-2)" "unprognostic (1.40e-3)" "unprognostic (1.79e-1)" "unprognostic (7.50e-2)" "unprognostic (1.75e-1)" "unprognostic (2.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.57e-5)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.4 0.1 0.0 0.1 0.0 0.0 5.1 0.0 0.0 0.4 0.5 0.0 0.0 1.2 0.0 2.2 2.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 4.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.4 0.5 2.2 2.1 1.4 1.5 0.5 0.5 0.0 0.0 1.1 0.7 0.0 0.3 0.7 2.0 0.0 0.0 0.1 0.1 1.7 0.0 6.3 0.0 0.0 0.3 0.0 2.0 0.0 0.0 42.7 31.0 0.2 0.3 0.0 0.0 2.9 0.0 0.1 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 3.6 1.3 0.0 0.0 0.0 17.1 0.0 0.1 0.0 0.0 1.0 0.0 0.0 2.5 1.7 0.0 0.8 0.0 0.0 0.5 1.3 0.0 77.8 0.0 0.0 0.2 1.0 0.9 8.8 0.5 0.6 0.0 0.1 0.0 1.9 0.3 DNAH5 "CILD3, Dnahc5, HL1, KTGNR, PCD" ENSG00000039139 "Dynein axonemal heavy chain 5" Q8TE73 5 13690328-14011818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;choroid plexus: 14.0" "Cell type enhanced" "Detected in many" "Club cells: 61.7;Endometrial ciliated cells: 190.3;Respiratory ciliated cells: 258.7" "Cancer enhanced" "Detected in many" "prostate cancer: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;LHCN-M2: 1.1;PC-3: 2.7;RPTEC TERT1: 1.3;TIME: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA037469, HPA037470" Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA037469: AB_10672791, HPA037470: AB_10672348" "unprognostic (3.85e-1)" "unprognostic (8.17e-2)" "unprognostic (5.94e-2)" "unprognostic (1.12e-1)" "unprognostic (4.58e-3)" "unprognostic (6.23e-2)" "unprognostic (3.33e-3)" "unprognostic (2.86e-2)" "unprognostic (9.94e-2)" "unprognostic (4.39e-2)" "unprognostic (1.59e-1)" "unprognostic (9.99e-2)" "unprognostic (9.97e-3)" "unprognostic (8.87e-2)" "unprognostic (8.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.65e-1)" 0.0 0.1 0.9 0.0 1.1 0.0 1.5 0.5 0.3 0.3 14.0 0.1 0.0 0.1 0.1 0.0 3.8 0.1 0.0 1.0 1.7 0.8 1.0 1.7 0.0 4.2 6.7 0.0 0.9 0.0 2.0 0.0 4.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 0.3 1.8 0.0 1.1 0.0 0.0 0.8 0.0 1.4 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.1 0.0 0.5 0.0 0.5 0.2 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.3 0.4 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.5 0.3 1.0 1.7 4.2 6.7 4.0 2.1 1.8 1.4 0.3 3.2 24.4 7.2 0.2 0.0 1.7 5.6 0.0 0.0 11.7 7.0 1.5 14.3 61.7 5.5 0.0 0.0 0.1 0.0 0.0 6.7 7.3 190.3 1.9 1.2 1.8 0.0 12.9 3.6 0.2 1.8 0.0 12.4 2.5 0.0 0.0 10.9 0.0 0.0 7.8 0.0 6.1 0.0 0.0 5.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 4.0 0.4 2.6 0.0 0.0 0.1 14.8 0.0 4.3 258.7 0.0 0.0 1.6 2.6 2.6 3.6 0.0 0.0 0.0 0.4 0.1 0.0 3.8 DNAJA4 PRO1472 ENSG00000140403 "DnaJ heat shock protein family (Hsp40) member A4" Q8WW22 15 78264086-78282196 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 138.4;tongue: 144.6" "Group enriched" "Detected in many" 5 "Early spermatids: 673.9;Late spermatids: 1608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 33.6;CAPAN-2: 43.3;HeLa: 47.3;MCF7: 33.6;RT4: 85.2;SCLC-21H: 53.3;SiHa: 42.7;THP-1: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004646, HPA041790" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "CAB004646: AB_426011, HPA041790: AB_2677674" "unprognostic (8.41e-2)" "unprognostic (2.48e-1)" "unprognostic (3.00e-2)" "unprognostic (8.20e-3)" "unprognostic (1.14e-3)" "unprognostic (1.99e-1)" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.86e-2)" "unprognostic (7.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.08e-7)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (9.01e-2)" "unprognostic (2.93e-2)" 16.5 20.0 60.6 14.0 67.7 63.7 12.6 62.6 138.4 14.1 45.6 18.0 13.8 8.3 20.2 15.8 38.9 11.2 123.3 68.6 93.1 26.7 3.3 19.7 11.3 65.7 73.3 12.1 6.6 7.4 30.9 9.5 89.8 26.7 18.5 33.0 15.6 15.6 123.2 28.6 16.3 19.6 59.8 13.5 24.2 78.3 73.5 9.4 9.6 144.6 12.4 29.6 13.6 71.3 33.6 0.2 0.0 0.0 0.0 0.0 0.1 4.1 0.0 1.1 0.5 0.0 43.3 0.0 0.3 3.2 0.0 31.3 0.0 0.0 0.1 0.1 0.0 19.9 47.3 0.0 9.4 0.0 20.6 3.6 4.1 2.6 0.0 0.0 6.6 0.0 0.0 0.0 0.4 33.6 0.0 0.0 0.0 14.4 0.3 0.0 0.0 0.0 0.1 85.2 53.3 0.0 42.7 8.6 3.6 2.3 32.4 39.8 0.5 0.0 8.7 4.0 0.4 0.6 2.4 0.0 0.1 4.2 0.0 0.0 0.3 1.1 0.6 0.3 1.0 0.7 0.9 0.9 0.4 0.1 1.7 1.4 0.0 0.1 0.4 0.2 0.5 0.6 60.6 67.7 62.6 138.4 68.6 93.1 65.7 73.3 89.8 59.8 73.5 71.3 41.9 6.4 4.8 12.7 10.0 28.8 209.9 14.0 2.2 19.6 44.6 29.2 43.6 2.8 33.5 7.3 81.3 1.9 6.7 55.5 1.9 1.3 673.9 124.0 11.4 18.9 100.3 92.8 16.6 2.4 3.8 18.3 21.4 41.8 36.9 7.5 6.8 0.2 16.5 6.7 24.0 34.9 10.2 9.5 81.7 1608.0 10.2 51.7 51.6 6.5 3.5 10.3 6.2 15.1 19.0 5.1 55.3 11.3 3.7 115.8 15.8 7.2 138.9 22.6 6.6 17.4 20.2 33.8 27.7 16.9 46.7 6.8 37.1 6.9 42.1 190.1 DOK5 "C20orf180, dJ805C22.1" ENSG00000101134 "Docking protein 5" Q9P104 20 54475593-54651169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 46.0;tongue: 24.3" "Cell type enhanced" "Detected in many" "Astrocytes: 110.7;Distal tubular cells: 39.2;Excitatory neurons: 49.7;Horizontal cells: 38.7;Inhibitory neurons: 79.6;Muller glia cells: 63.9;Oligodendrocyte precursor cells: 58.3" "Group enriched" "Detected in many" 6 "glioma: 18.0;ovarian cancer: 29.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 32.9;ASC diff: 13.1;ASC TERT1: 11.0;hTEC/SVTERT24-B: 13.7;U-138 MG: 51.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054460, HPA065235" Uncertain Approved "Focal adhesion sites" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "HPA054460: AB_2682495, HPA065235: AB_2685441" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (8.90e-2)" "prognostic unfavorable (8.99e-7)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-4)" "unprognostic (5.12e-2)" "unprognostic (4.51e-3)" "unprognostic (2.97e-1)" "unprognostic (2.69e-2)" "unprognostic (1.49e-1)" "unprognostic (6.49e-2)" "unprognostic (4.23e-3)" "unprognostic (3.08e-1)" "unprognostic (4.56e-2)" "unprognostic (1.99e-2)" 2.9 1.9 14.6 1.7 14.2 0.0 1.9 13.4 15.6 1.1 13.0 1.4 0.3 1.7 0.3 1.7 12.2 9.8 18.4 15.4 16.9 5.2 2.3 1.0 0.6 15.9 14.7 0.9 1.2 0.2 1.1 1.8 18.6 0.9 0.7 11.7 1.4 0.8 46.0 0.5 0.7 2.8 13.9 0.3 0.8 1.7 15.3 0.4 5.1 24.3 0.4 4.7 0.9 13.3 0.0 0.0 32.9 0.0 13.1 11.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 5.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 4.3 0.0 13.7 0.0 0.6 1.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 3.6 7.0 0.0 8.6 0.0 0.0 0.1 0.4 1.9 0.0 0.0 0.0 51.3 3.2 1.4 0.0 0.0 0.0 0.1 2.3 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 14.2 13.4 15.6 15.4 16.9 15.9 14.7 18.6 13.9 15.3 13.3 4.8 0.0 0.0 110.7 0.3 0.3 2.3 0.0 0.0 12.3 6.7 6.2 7.3 12.8 0.0 11.0 6.2 0.3 0.1 0.0 39.2 17.7 2.3 0.4 1.5 3.3 0.0 0.0 49.7 1.2 0.6 14.4 0.0 10.6 0.0 28.6 17.5 0.0 29.0 38.7 79.6 0.0 0.0 0.6 2.5 4.5 2.5 0.6 0.0 9.4 14.5 63.9 0.0 58.3 2.1 2.2 0.0 1.2 0.1 2.0 0.0 0.2 0.0 8.1 0.0 2.8 5.3 3.7 1.5 0.0 0.4 0.8 0.2 1.6 0.0 0.9 DPCD "DKFZP566F084, RP11-529I10.4" ENSG00000166171 "Deleted in primary ciliary dyskinesia homolog (mouse)" Q9BVM2 10 101570560-101609662 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 132.4" "Group enriched" "Detected in many" 4 "Early spermatids: 579.4;Late spermatids: 1068.7;Respiratory ciliated cells: 329.7;Spermatocytes: 313.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 20.2;intermediate monocyte: 22.2;myeloid DC: 29.6;non-classical monocyte: 9.5" "Group enriched" "Detected in all" 14 "dendritic cells: 29.6;monocytes: 22.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036603, HPA036604" Enhanced Approved "Nuclear speckles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA036603: AB_2675212, HPA036604: AB_10673503" "unprognostic (1.22e-2)" "unprognostic (1.73e-3)" "unprognostic (4.66e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.90e-1)" "unprognostic (9.13e-2)" "unprognostic (4.00e-3)" "unprognostic (1.71e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (5.04e-2)" "unprognostic (3.83e-2)" "unprognostic (7.54e-2)" 10.5 18.7 35.1 8.7 37.2 11.8 19.4 31.5 42.0 21.8 55.1 17.3 6.8 16.7 41.3 20.4 73.3 15.5 29.6 37.4 39.1 30.9 10.4 14.0 6.2 36.2 37.1 23.5 14.7 49.3 49.5 10.6 36.5 16.1 13.5 55.8 21.2 15.7 19.2 13.2 7.1 18.0 33.3 4.5 14.4 132.4 39.7 6.6 33.0 18.3 8.2 14.4 14.9 33.4 97.1 53.4 37.9 77.2 35.2 61.7 15.6 44.5 53.6 59.4 55.1 38.8 51.4 9.0 74.6 42.7 25.2 54.0 55.4 65.3 61.2 23.0 57.5 11.3 49.8 56.7 20.3 58.8 8.1 42.3 54.8 72.0 56.1 153.7 50.8 14.0 32.4 12.6 45.1 122.9 0.0 48.1 28.7 26.9 41.6 0.0 51.8 20.5 92.6 25.3 37.1 63.3 36.5 23.4 31.3 34.1 71.2 23.9 35.5 27.3 24.9 55.7 62.3 37.9 45.9 16.9 94.7 13.7 11.7 0.0 20.2 1.0 1.8 22.2 1.7 1.3 1.4 1.4 29.6 0.7 1.5 1.8 0.9 1.6 9.5 4.1 0.6 8.1 35.1 37.2 31.5 42.0 37.4 39.1 36.2 37.1 36.5 33.3 39.7 33.4 6.9 35.3 12.4 4.9 2.1 9.7 29.5 89.2 9.6 16.4 25.4 29.5 33.7 30.0 56.6 49.7 18.8 24.6 0.9 10.5 95.9 63.3 579.4 136.5 23.5 11.1 23.9 14.1 7.7 27.5 16.7 21.2 10.2 20.2 1.3 19.2 11.4 10.9 24.0 11.8 6.2 12.5 52.9 4.4 14.6 1068.7 23.6 8.7 16.0 3.7 6.9 27.8 2.1 4.0 1.4 33.9 12.4 27.8 5.6 18.6 3.5 117.3 329.7 49.1 0.0 12.4 29.0 313.8 77.4 8.7 14.2 10.7 2.9 25.3 22.1 23.9 DPP10 "DPL2, DPPY, DPRP3" ENSG00000175497 "Dipeptidyl peptidase like 10" Q8N608 2 114442299-115845780 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 10.7;brain: 20.2;pancreas: 17.3" "Cell type enhanced" "Detected in many" "Astrocytes: 4634.9;Excitatory neurons: 3067.4;Inhibitory neurons: 3258.7;Oligodendrocyte precursor cells: 990.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.1;HAP1: 6.2;HMC-1: 4.3;JURKAT: 3.4;NTERA-2: 3.7;RT4: 6.7;SCLC-21H: 9.7;SH-SY5Y: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048767 Uncertain NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA048767: AB_2680515" "unprognostic (1.19e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (6.59e-2)" "unprognostic (2.92e-1)" "unprognostic (5.35e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (8.33e-2)" "unprognostic (7.61e-2)" "unprognostic (4.22e-2)" 0.2 10.7 12.4 0.3 20.2 0.1 0.0 0.0 16.6 0.3 0.0 2.2 1.2 0.4 0.0 0.0 0.1 0.8 0.1 19.3 0.5 0.2 0.1 0.2 0.0 1.9 3.1 0.0 17.3 0.0 0.8 0.8 2.0 0.0 2.8 4.1 0.2 0.0 0.0 0.1 1.2 0.8 4.5 0.0 1.0 1.0 6.0 0.0 0.6 0.0 0.0 0.3 0.0 11.7 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 6.7 9.7 3.9 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 20.2 0.0 16.6 19.3 0.5 1.9 3.1 2.0 4.5 6.0 11.7 0.0 0.0 0.0 4634.9 0.0 0.0 0.0 0.0 0.6 21.7 0.0 0.0 1.5 4.3 0.6 0.0 0.0 1.5 0.0 2.3 0.0 0.0 12.4 0.1 0.1 0.1 4.2 2.1 3067.4 2.7 10.2 0.5 0.0 0.3 0.0 5.8 0.7 0.0 0.3 5.0 3258.7 1.4 0.0 0.0 0.0 5.7 0.3 0.0 1.8 58.1 0.0 1.4 0.0 990.7 48.3 0.8 1.9 0.0 0.0 0.0 0.2 0.2 0.0 0.7 0.0 0.0 0.1 1.6 2.6 0.3 0.0 4.4 0.0 0.4 3.2 0.0 DPY19L2 "FLJ32949, SPATA34" ENSG00000177990 "Dpy-19 like 2" Q6NUT2 12 63558913-63668939 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.6" "Group enriched" "Detected in many" 4 "Early spermatids: 329.9;Excitatory neurons: 124.1;Inhibitory neurons: 137.2;Late spermatids: 363.0;Oligodendrocyte precursor cells: 124.1;Spermatocytes: 143.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 9.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA071264, HPA078305" Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Mitochondria Nucleoplasm "HPA071264: AB_2686375, HPA078305: " "unprognostic (1.97e-1)" "unprognostic (4.08e-1)" "unprognostic (4.46e-3)" "unprognostic (2.50e-2)" "unprognostic (1.64e-1)" "unprognostic (1.17e-4)" "unprognostic (2.28e-2)" "unprognostic (2.14e-3)" "unprognostic (1.53e-1)" "unprognostic (3.64e-1)" "unprognostic (3.99e-3)" "unprognostic (1.97e-1)" "unprognostic (6.31e-3)" "unprognostic (4.22e-3)" "unprognostic (5.88e-2)" "unprognostic (8.90e-3)" "unprognostic (1.79e-1)" 6.7 5.3 4.0 0.5 3.9 3.0 4.7 7.0 6.9 11.4 6.6 5.2 0.6 7.8 4.1 1.4 6.4 2.8 19.2 3.0 4.3 12.7 0.2 1.3 0.9 2.4 3.0 11.0 2.7 9.0 10.5 1.2 1.5 9.3 1.3 14.4 1.6 4.7 0.5 1.6 1.7 3.5 0.8 1.7 2.9 65.6 3.3 0.7 13.1 0.6 0.6 6.3 5.1 4.2 1.0 2.6 2.2 5.4 0.6 0.0 0.2 1.8 1.8 2.4 3.1 0.4 0.8 2.8 1.8 0.7 2.9 0.4 2.7 0.3 3.6 1.5 1.7 4.6 1.4 1.7 0.5 3.4 1.4 1.5 0.1 1.1 0.0 6.1 0.8 2.2 1.9 2.9 3.9 1.7 0.2 1.4 2.1 0.4 2.4 0.0 1.8 0.0 4.6 0.5 7.0 0.7 0.6 0.2 1.0 0.9 1.9 0.9 0.5 3.2 4.2 0.5 4.6 7.5 9.3 0.0 3.4 1.6 3.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 4.0 3.9 7.0 6.9 3.0 4.3 2.4 3.0 1.5 0.8 3.3 4.2 6.7 3.2 0.0 23.2 0.2 0.5 2.9 0.1 2.2 49.6 1.9 1.8 32.3 1.5 3.8 12.9 14.6 2.0 0.3 0.1 5.9 0.4 329.9 5.6 7.1 1.7 0.0 7.2 124.1 0.0 1.3 2.2 0.5 2.1 2.5 1.2 1.4 0.1 0.3 3.3 137.2 0.1 6.1 0.0 0.4 363.0 7.2 0.4 7.2 11.2 0.1 9.2 0.0 124.1 5.0 0.2 0.0 8.6 0.5 2.9 0.0 6.4 11.6 6.7 26.3 3.8 19.9 143.3 4.9 0.2 0.4 1.4 0.8 3.6 0.1 1.1 DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1712.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" 22.2 13.2 7.2 22.6 12.8 10.3 16.7 5.7 10.4 18.8 2.4 11.9 21.9 14.9 8.4 17.1 14.3 25.7 8.9 7.4 12.9 12.6 68.5 29.6 16.6 12.4 9.4 24.0 11.8 9.2 6.2 4.5 12.1 9.9 10.1 3.3 15.0 13.4 5.8 7.1 19.4 18.2 6.9 24.7 8.4 3.7 12.9 17.0 10.3 10.1 12.0 18.2 14.2 24.4 22.2 6.2 7.8 0.2 42.4 72.5 0.1 35.2 31.9 32.1 23.6 0.0 9.2 11.7 50.6 32.9 5.1 5.2 0.0 8.3 58.7 11.6 7.3 10.0 11.1 0.2 18.8 4.5 0.6 57.5 3.0 25.7 29.3 67.7 26.8 6.8 0.4 36.4 17.0 0.0 23.6 6.4 0.9 0.2 7.5 0.1 37.1 18.6 39.4 0.1 11.1 8.8 30.1 2.5 0.3 0.8 0.0 10.2 30.9 69.2 5.0 56.4 70.6 3.0 0.1 0.2 10.2 12.6 56.2 18.2 61.1 4.1 11.6 29.5 14.8 2.2 13.3 11.0 32.7 4.9 12.5 11.1 59.8 13.3 27.1 0.9 15.8 21.9 7.2 12.8 5.7 10.4 7.4 12.9 12.4 9.4 12.1 6.9 12.9 24.4 25.5 16.0 39.1 23.8 15.4 7.6 8.8 9.4 18.8 2.5 8.4 8.3 5.3 40.0 11.5 7.3 0.0 0.2 19.2 3.3 5.9 2.5 7.0 1.5 15.2 14.7 3.0 13.3 258.6 6.4 0.2 30.0 10.7 1.7 9.5 4.5 17.2 54.2 17.1 0.0 30.5 5.5 6.1 130.4 27.0 4.0 33.5 73.7 3.6 105.9 98.1 4.8 27.8 34.2 1712.3 5.3 2.1 18.8 17.0 4.9 21.0 6.6 8.6 0.1 13.1 16.0 17.7 1.2 3.1 19.7 5.5 0.1 31.4 5.1 6.8 9.3 DQX1 FLJ23757 ENSG00000144045 "DEAQ-box RNA dependent ATPase 1" Q8TE96 2 74518131-74526281 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 16.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 17.3;Gastric mucus-secreting cells: 13.7;Intestinal goblet cells: 17.3;Paneth cells: 13.9;Proximal enterocytes: 44.2;Undifferentiated cells: 12.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HBEC3-KT: 5.8;Hep G2: 18.4;hTCEpi: 6.1;OE19: 15.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039158, HPA046763" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoli fibrillar center" "HPA039158: AB_10960125, HPA046763: " "unprognostic (2.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (9.95e-2)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-1)" "unprognostic (4.54e-2)" "unprognostic (1.68e-1)" "unprognostic (7.67e-2)" "unprognostic (2.21e-2)" "unprognostic (0.00e+0)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-3)" 0.0 0.0 0.1 0.6 0.1 0.0 0.1 0.0 0.2 0.4 0.0 6.3 16.4 0.0 0.0 1.6 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.0 5.6 0.0 0.4 0.0 0.0 1.1 13.9 0.5 0.0 0.1 3.2 0.0 0.1 0.0 0.0 0.0 1.0 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.6 0.1 5.8 0.1 0.0 0.0 0.5 0.2 18.4 0.0 0.2 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 15.5 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 0.0 2.4 0.0 0.9 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.5 0.5 0.1 4.5 4.6 0.4 0.1 0.0 0.3 1.5 3.5 0.0 2.1 1.6 0.0 17.3 0.0 0.0 0.0 0.2 0.1 0.0 2.4 0.0 0.6 0.0 0.8 0.6 13.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 17.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 13.9 0.0 0.4 0.0 44.2 0.0 5.0 0.9 0.0 0.1 0.1 0.6 0.3 3.1 0.0 1.1 0.1 0.0 12.5 0.2 DR1 "NC2-BETA, NC2B, NCB2" ENSG00000117505 "Down-regulator of transcription 1" Q01658 1 93345907-93369493 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050785, HPA055308" Enhanced Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA050785: AB_2681237, HPA055308: AB_2682779" "unprognostic (1.46e-1)" "unprognostic (9.62e-2)" "prognostic favorable (4.79e-4)" "unprognostic (1.03e-2)" "unprognostic (2.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.95e-7)" "unprognostic (8.70e-2)" "unprognostic (6.71e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.07e-1)" "unprognostic (2.29e-1)" "unprognostic (4.97e-1)" "unprognostic (1.60e-1)" 21.8 18.9 9.8 28.8 9.6 59.1 16.8 12.5 9.3 17.7 23.7 18.2 27.2 21.0 11.1 30.0 14.2 23.1 27.0 8.7 10.8 21.8 20.4 19.6 43.3 9.9 9.8 15.9 18.8 16.9 12.1 32.0 9.5 17.1 16.3 14.1 19.5 14.0 50.4 29.4 22.4 19.2 10.3 27.0 30.2 55.7 10.5 47.7 18.7 42.9 30.8 27.3 22.6 10.5 97.1 29.8 46.8 60.6 42.3 47.9 57.5 76.5 46.6 50.9 54.0 34.9 34.1 101.9 86.4 56.7 69.3 50.1 56.7 53.0 74.6 86.4 53.0 85.8 58.7 38.4 67.3 102.1 60.6 33.7 62.4 71.2 102.2 53.1 45.9 60.0 90.0 95.7 61.0 29.8 97.6 32.1 78.1 33.4 72.1 83.5 103.2 104.0 36.3 58.0 45.3 57.6 65.1 59.7 80.6 42.2 42.2 79.4 72.1 91.5 73.0 90.7 116.0 54.9 65.6 105.5 26.3 80.3 38.2 95.2 46.2 82.1 35.3 52.7 39.2 36.9 38.8 40.4 55.9 31.5 38.6 37.8 62.8 35.5 47.4 45.4 57.1 41.3 9.8 9.6 12.5 9.3 8.7 10.8 9.9 9.8 9.5 10.3 10.5 10.5 36.2 28.9 22.1 10.1 43.5 171.3 38.0 38.7 47.3 32.0 29.1 24.1 33.9 22.8 27.9 36.8 25.0 74.5 84.6 42.8 45.0 31.4 183.1 18.4 33.7 37.5 20.8 59.3 8.4 27.7 73.6 34.3 38.2 24.2 48.9 19.7 29.3 27.6 53.0 50.5 8.7 42.6 10.2 50.8 82.8 106.2 28.3 55.2 44.4 15.0 68.0 16.0 69.0 7.5 10.8 52.9 25.9 26.4 31.9 51.6 29.8 40.7 17.6 25.3 32.9 27.7 42.0 163.2 41.2 69.4 160.5 109.9 59.8 26.2 26.9 79.2 DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 164.0;vagina: 97.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 384.0;Paneth cells: 324.8;Squamous epithelial cells: 705.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 28.9;neutrophil: 8.1" "Lineage enriched" "Detected in many" 14 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "BEWO: 37.6;CAPAN-2: 48.3;HaCaT: 71.1;hTCEpi: 76.0;OE19: 60.7;SK-BR-3: 44.4;SuSa: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Plasma membrane,Cytosol" NA NA 24000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" 5.5 1.8 1.3 12.7 1.4 0.7 22.2 1.3 1.6 59.2 1.9 50.5 41.6 1.5 5.9 164.0 6.1 3.7 10.6 1.2 2.0 5.9 7.3 7.9 3.7 2.6 1.5 0.6 10.5 27.0 0.5 21.3 2.2 15.8 44.5 1.0 46.8 1.0 0.3 11.9 42.9 4.0 1.8 3.0 43.2 0.8 1.6 6.6 4.0 3.1 62.2 3.6 97.4 2.3 18.1 1.9 2.9 0.0 0.0 0.0 37.6 0.0 0.0 0.0 0.0 9.8 48.3 0.0 0.7 0.0 0.9 71.1 11.8 4.9 0.0 0.0 6.9 27.1 8.4 16.9 0.3 0.2 0.5 0.4 76.0 0.0 7.3 6.1 0.0 0.0 13.4 0.0 0.0 14.7 0.0 1.1 11.3 60.7 17.4 13.2 0.0 0.2 0.1 0.7 0.0 0.1 0.0 44.4 0.0 43.4 12.2 18.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 28.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.4 1.3 1.4 1.3 1.6 1.2 2.0 2.6 1.5 2.2 1.8 1.6 2.3 25.1 28.9 5.6 3.3 1.0 83.7 44.5 16.4 67.7 0.8 75.3 65.7 33.8 32.9 11.1 7.3 0.0 100.8 1.0 384.0 0.0 83.5 0.1 19.1 4.0 6.7 69.4 0.4 3.3 33.2 186.6 5.9 47.4 43.8 0.0 2.7 8.2 16.0 24.8 0.0 1.5 83.1 20.3 48.8 29.3 0.2 0.3 35.3 14.2 4.7 25.2 11.2 0.0 2.0 0.2 155.7 324.8 0.7 0.3 140.6 118.2 9.7 3.8 0.7 0.0 1.2 3.0 0.1 1.3 705.6 55.0 83.9 2.0 0.3 114.0 76.1 DSCAM "CHD2-42, CHD2-52" ENSG00000171587 "DS cell adhesion molecule" O60469 21 40010999-40847158 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.6;pituitary gland: 4.2;retina: 1.9" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 4376.6" "Cancer enriched" "Detected in single" 14 "glioma: 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 3.6;MCF7: 8.3;NTERA-2: 2.2;SCLC-21H: 3.3;T-47d: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019324, HPA057493" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA019324: AB_2670118, HPA057493: " "unprognostic (1.47e-2)" "unprognostic (1.04e-1)" "unprognostic (7.59e-2)" "unprognostic (1.99e-2)" "unprognostic (9.98e-2)" "unprognostic (5.49e-4)" "unprognostic (1.78e-1)" "unprognostic (9.58e-2)" "unprognostic (7.95e-2)" "unprognostic (1.53e-1)" "unprognostic (8.85e-3)" "unprognostic (2.12e-2)" "unprognostic (2.00e-3)" "unprognostic (2.17e-2)" "unprognostic (2.29e-1)" "unprognostic (8.75e-2)" "unprognostic (5.46e-3)" 0.0 0.0 5.4 0.0 5.8 0.0 0.1 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 5.6 4.2 0.0 0.1 0.0 0.0 2.3 2.8 0.0 0.1 0.0 4.2 0.7 3.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.8 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.8 0.1 6.6 5.6 4.2 2.3 2.8 3.5 2.9 4.1 4.1 0.0 0.0 0.0 19.9 0.0 0.0 0.1 0.0 0.0 19.6 0.0 0.4 1.1 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.4 0.0 0.0 1083.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 16.8 649.1 0.0 0.0 2.4 0.0 4.2 0.0 0.0 0.0 200.5 0.0 0.7 0.0 4376.6 21.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 2.0 0.1 1.7 1.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 DTNB ENSG00000138101 "Dystrobrevin beta" O60941 2 25377198-25673647 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 36.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.8;Inhibitory neurons: 214.1;Oligodendrocyte precursor cells: 137.7;Oligodendrocytes: 343.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA061357 Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA061357: AB_2684489" "unprognostic (1.14e-1)" "unprognostic (1.39e-2)" "unprognostic (3.17e-2)" "unprognostic (7.40e-2)" "unprognostic (1.17e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.78e-2)" "unprognostic (3.67e-3)" "unprognostic (3.98e-2)" "unprognostic (9.45e-2)" "unprognostic (4.67e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.16e-2)" "unprognostic (6.49e-2)" 2.1 2.1 7.8 1.6 6.7 2.9 9.7 3.4 12.1 4.2 0.0 1.7 1.2 2.8 10.1 4.5 4.6 3.3 2.0 12.4 3.6 4.2 3.4 4.3 2.5 4.9 1.7 4.4 7.7 9.9 5.8 1.9 4.5 8.4 1.0 5.0 36.0 5.1 2.7 4.5 1.6 1.2 0.1 2.7 5.6 6.7 2.9 4.0 11.1 1.5 1.9 3.5 4.0 5.6 10.7 9.1 6.6 7.5 4.0 5.2 0.2 3.2 4.2 4.0 5.3 3.5 2.6 5.5 1.3 2.5 5.0 3.7 4.6 13.1 2.2 8.2 11.1 4.5 2.9 10.0 2.9 5.4 4.1 3.6 10.9 4.2 7.2 4.9 5.5 10.5 0.4 8.0 3.0 10.9 8.5 4.6 7.3 2.9 5.4 7.0 11.5 9.7 4.9 9.7 8.9 13.7 10.3 16.2 12.9 3.6 8.7 3.3 2.3 1.6 7.3 2.4 5.7 14.6 6.8 10.0 4.6 9.5 5.7 0.4 1.6 5.7 4.1 0.9 4.4 4.4 5.0 3.7 0.5 5.8 5.0 3.3 3.2 4.1 0.4 0.9 5.2 2.0 7.8 6.7 3.4 12.1 12.4 3.6 4.9 1.7 4.5 0.1 2.9 5.6 3.9 9.6 12.8 53.2 12.6 8.0 26.6 16.4 44.3 9.4 20.3 18.9 2.3 7.2 9.3 14.7 6.2 3.7 4.2 0.9 11.7 4.0 3.1 7.2 4.2 4.7 3.0 4.4 176.8 11.6 1.5 3.2 15.8 12.1 1.3 4.6 5.0 5.6 33.6 21.9 214.1 2.8 14.2 7.8 1.7 6.9 1.5 4.9 12.4 83.4 3.2 18.5 7.2 137.7 343.3 9.5 1.4 2.6 8.7 17.9 0.3 9.3 2.2 9.9 6.6 1.9 3.2 12.6 27.9 15.7 2.0 2.1 10.8 2.3 1.3 17.7 DYNLL1 "DLC1, DLC8, DNCL1, hdlc1, LC8, PIN" ENSG00000088986 "Dynein light chain LC8-type 1" P63167 12 120469850-120498493 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Transcription, Transcription regulation, Transport" "Activator, Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 4098.6;Respiratory ciliated cells: 2679.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA Yes 890000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039954: AB_2676771" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (2.88e-2)" "unprognostic (5.63e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (4.41e-3)" "unprognostic (4.64e-2)" "unprognostic (6.17e-3)" "unprognostic (1.61e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (7.97e-7)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (7.91e-2)" "unprognostic (1.62e-1)" 268.6 261.9 912.5 186.7 967.7 126.8 268.0 895.2 1292.9 354.2 894.7 325.8 162.8 319.4 322.3 719.9 544.2 242.7 257.5 975.4 944.7 352.6 238.4 222.6 241.6 896.1 898.5 247.0 225.1 228.2 309.7 259.2 914.2 225.9 327.4 181.3 245.4 264.6 85.6 626.7 206.3 390.1 935.1 185.2 244.5 360.3 909.7 306.5 176.1 163.9 357.8 389.8 474.4 1001.2 721.6 811.4 779.2 600.8 677.1 713.6 250.8 968.0 451.6 785.6 466.7 770.8 472.3 400.6 510.3 945.1 753.0 629.6 949.3 818.3 781.0 528.3 617.9 390.4 532.9 1062.5 676.2 412.8 620.5 436.2 863.0 584.6 477.5 855.7 831.8 421.5 502.0 446.1 1056.8 960.1 541.4 894.8 642.2 917.7 935.7 543.0 403.0 499.2 1143.1 659.8 535.2 392.0 789.3 677.7 926.6 812.6 673.6 595.3 635.2 592.3 502.1 525.6 852.2 264.0 562.8 404.6 656.8 645.1 776.6 516.6 291.9 384.2 200.6 303.3 155.3 310.4 207.2 211.7 281.8 219.0 132.0 165.7 50.1 282.9 334.8 461.6 373.5 353.0 912.5 967.7 895.2 1292.9 975.4 944.7 896.1 898.5 914.2 935.1 909.7 1001.2 810.1 195.5 101.9 79.3 341.4 922.2 359.1 1275.0 356.8 138.4 800.0 949.4 170.8 303.1 764.6 399.1 83.4 524.6 484.1 689.9 1113.2 691.2 1407.2 1842.5 528.5 541.9 480.8 332.9 111.2 538.9 897.4 538.5 240.5 488.1 316.7 611.9 521.9 499.0 732.1 85.8 62.8 801.6 1121.0 329.4 706.1 4098.6 516.6 466.3 595.9 42.2 701.6 164.0 248.2 47.3 156.4 754.9 798.6 701.8 234.9 304.7 533.4 1125.0 2679.6 193.5 368.1 440.7 1016.3 961.5 721.4 1005.4 1610.1 1006.6 396.6 586.3 498.2 389.6 DYNLRB1 "DNCL2A, DNLC2A, ROBLD1" ENSG00000125971 "Dynein light chain roadblock-type 1" Q9NP97 20 34516414-34540958 "Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 781.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009845 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "CAB009845: AB_2093671" "unprognostic (2.23e-1)" "unprognostic (7.60e-3)" "unprognostic (5.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (6.44e-4)" "unprognostic (9.10e-2)" "unprognostic (3.41e-2)" "unprognostic (7.79e-2)" "unprognostic (1.71e-1)" "unprognostic (2.11e-1)" "unprognostic (7.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.00e-1)" 168.7 208.4 430.4 96.9 440.2 113.7 163.7 416.5 552.8 163.7 400.8 228.4 113.8 193.0 204.9 155.4 198.5 117.1 275.7 448.5 454.1 265.8 122.0 169.4 123.9 444.7 443.3 153.9 115.0 222.9 204.3 154.6 436.7 180.9 128.2 171.7 142.1 170.7 222.8 222.1 156.4 158.7 416.1 143.0 166.7 66.6 422.8 154.3 174.4 224.5 135.1 191.4 158.8 458.8 244.4 317.6 259.4 207.3 307.5 294.9 175.4 264.1 393.5 399.2 340.7 853.3 231.1 135.6 327.4 402.0 385.5 215.3 282.2 391.6 265.9 164.5 198.8 463.2 286.8 679.1 345.7 217.5 249.6 251.4 250.4 320.2 245.7 306.2 282.2 255.8 195.1 249.0 415.5 313.4 314.7 427.4 148.6 284.7 345.2 158.6 359.6 220.2 618.7 160.8 264.2 273.9 382.9 631.9 359.4 249.2 362.5 240.7 251.9 500.8 122.4 351.2 295.8 208.8 310.3 157.3 430.1 186.7 225.0 225.4 112.5 221.2 88.0 123.1 88.8 144.2 145.6 117.2 128.8 127.3 101.4 102.1 111.4 132.4 144.3 161.2 238.7 135.0 430.4 440.2 416.5 552.8 448.5 454.1 444.7 443.3 436.7 416.1 422.8 458.8 188.4 169.9 106.5 26.1 107.9 146.8 176.8 215.9 100.2 105.4 136.0 200.3 125.5 170.1 157.4 292.4 58.4 297.8 112.9 283.9 481.3 264.4 34.0 266.4 139.5 170.9 226.7 98.2 34.7 223.4 211.4 149.1 85.1 208.5 159.0 149.8 162.4 104.1 287.9 80.8 30.0 284.6 256.3 127.8 131.5 51.0 234.9 139.1 193.9 19.7 236.2 435.8 148.3 20.1 61.4 317.5 379.3 240.3 117.0 240.4 388.9 781.8 253.1 127.6 203.8 101.8 210.8 65.6 77.2 106.3 150.0 342.3 124.9 90.9 160.5 184.3 DYRK3 "hYAK3-2, RED, REDK" ENSG00000143479 "Dual specificity tyrosine phosphorylation regulated kinase 3" O43781 1 206635536-206684419 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 48.0" "Cell type enhanced" "Detected in many" "Early spermatids: 235.3;Late spermatids: 48.1;Spermatocytes: 108.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-HME1: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075041 Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA075041: AB_2686730" "unprognostic (6.51e-2)" "unprognostic (1.24e-2)" "unprognostic (3.36e-2)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-4)" "unprognostic (2.69e-1)" "unprognostic (3.91e-1)" "unprognostic (2.71e-1)" "unprognostic (2.79e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (9.41e-7)" "unprognostic (2.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (7.62e-3)" 7.6 2.4 3.7 4.2 3.8 8.8 5.7 1.7 3.7 5.6 5.6 2.3 1.0 5.3 3.1 2.8 5.7 13.5 8.3 5.1 3.8 3.3 4.1 5.5 1.6 3.8 5.1 4.9 3.9 3.0 6.5 1.2 3.4 2.9 1.4 6.4 4.3 3.0 0.8 1.5 1.7 8.1 2.6 1.3 3.1 48.0 3.8 5.9 8.3 1.9 1.8 7.5 2.8 3.5 5.0 6.7 1.6 9.8 16.7 15.9 0.4 15.4 36.7 15.0 19.6 0.4 2.7 7.6 2.2 20.1 25.8 1.5 8.6 14.1 15.8 0.1 4.8 10.5 8.9 1.7 26.9 7.5 6.8 10.9 8.9 25.6 73.6 15.1 11.8 11.6 20.1 1.4 23.2 2.0 16.9 4.4 13.2 0.5 10.8 41.1 4.9 0.1 4.8 0.4 9.3 6.9 13.6 0.6 20.3 2.0 2.0 1.9 8.1 31.1 11.2 14.8 13.2 5.6 2.2 9.1 17.7 8.3 2.9 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.5 0.0 0.0 2.7 0.0 0.0 3.7 3.8 1.7 3.7 5.1 3.8 3.8 5.1 3.4 2.6 3.8 3.5 13.9 3.2 8.2 4.2 1.0 6.5 10.7 9.6 3.4 0.2 4.7 3.3 10.8 1.5 4.2 1.8 10.4 0.0 1.5 0.3 0.0 5.1 235.3 12.6 8.0 8.5 2.4 23.6 3.6 2.2 0.1 12.7 1.1 5.9 0.0 3.4 3.9 1.1 1.0 0.0 1.5 0.4 2.0 1.0 4.6 48.1 4.1 2.9 8.8 1.0 1.0 3.4 0.0 2.5 0.3 1.2 1.2 1.9 2.1 3.8 0.2 1.7 10.5 8.2 6.6 10.2 10.4 108.7 6.4 1.3 3.7 0.4 2.4 3.0 0.6 5.3 E2F7 ENSG00000165891 "E2F transcription factor 7" Q96AV8 12 77021248-77065569 "Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.3" "Cell type enhanced" "Detected in many" "Early spermatids: 46.9;Endometrial ciliated cells: 17.2;Late spermatids: 70.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "midbrain: 5.8;pons: 6.4;thalamus: 11.3" HPA064866 Supported "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA064866: AB_2685374" "unprognostic (1.21e-1)" "unprognostic (8.92e-2)" "unprognostic (7.39e-2)" "unprognostic (7.27e-2)" "unprognostic (1.54e-1)" "unprognostic (3.80e-2)" "unprognostic (6.14e-5)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (3.57e-2)" "unprognostic (5.67e-5)" "unprognostic (1.42e-1)" "unprognostic (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.00e-1)" "unprognostic (2.51e-1)" 0.2 0.1 0.2 1.1 0.2 5.0 0.2 0.0 0.3 0.3 0.3 0.9 0.7 0.2 0.0 1.4 0.6 0.7 0.2 0.2 0.2 0.1 0.2 0.3 1.5 0.7 0.8 0.1 0.2 0.1 0.5 1.0 0.4 0.2 1.5 0.2 0.2 0.1 0.0 1.1 0.8 0.3 0.6 0.3 0.6 2.9 0.2 8.3 0.1 0.1 1.6 0.6 0.5 0.2 20.1 9.4 25.7 10.1 0.8 2.5 31.1 27.6 29.8 14.2 17.0 12.8 6.6 11.2 5.4 5.5 29.5 15.1 15.5 29.8 27.1 4.4 10.4 9.8 27.3 7.3 5.9 8.5 8.8 0.8 7.7 37.4 22.9 8.3 14.2 19.0 10.4 8.9 29.5 10.1 31.9 0.1 18.1 6.7 21.9 23.0 22.2 6.2 3.5 16.8 16.3 10.7 22.9 7.9 6.5 10.9 12.6 8.7 39.3 53.5 26.8 23.0 36.7 9.5 5.8 7.1 19.3 3.8 34.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.4 0.0 0.2 0.2 0.0 0.3 0.2 0.2 0.7 0.8 0.4 0.6 0.2 0.2 0.1 0.0 0.5 2.3 0.5 0.3 1.0 1.4 4.6 0.0 0.6 0.9 2.1 0.0 2.2 0.0 0.0 1.8 0.4 1.5 0.0 0.3 46.9 17.2 0.8 1.5 0.0 7.4 0.4 1.1 3.1 0.8 6.1 3.1 4.5 6.3 0.0 0.0 0.9 0.0 0.2 1.2 2.0 0.3 1.2 70.2 0.3 1.3 0.0 3.7 0.0 1.6 0.0 0.5 0.0 12.0 0.1 0.7 6.9 1.7 0.0 0.0 3.1 0.1 0.0 0.0 1.2 1.2 2.1 6.3 0.6 0.3 0.8 0.4 2.1 4.3 E2F8 FLJ23311 ENSG00000129173 "E2F transcription factor 8" A0AVK6 11 19224063-19241620 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.2;lymphoid tissue: 11.8;skeletal muscle: 12.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 34.1;Gastric mucus-secreting cells: 10.2;Plasma cells: 9.7;Squamous epithelial cells: 10.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA064882, HPA076614" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytosol" "HPA064882: AB_2685381, HPA076614: " "unprognostic (5.62e-2)" "unprognostic (5.24e-2)" "unprognostic (3.17e-2)" "unprognostic (6.99e-3)" "unprognostic (2.86e-2)" "unprognostic (1.66e-2)" "unprognostic (1.29e-5)" "unprognostic (1.94e-2)" "unprognostic (3.90e-3)" "unprognostic (2.41e-1)" "unprognostic (7.29e-4)" "unprognostic (1.16e-2)" "unprognostic (9.13e-8)" "unprognostic (1.02e-3)" "unprognostic (1.37e-1)" "unprognostic (3.81e-1)" "unprognostic (4.28e-3)" 0.3 0.1 0.0 2.8 0.0 14.2 0.5 0.1 0.1 1.0 0.0 4.0 3.8 0.4 0.0 4.9 0.9 0.4 2.1 0.0 0.0 0.1 0.3 0.3 7.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.4 5.1 0.0 0.9 0.2 12.6 3.0 3.0 0.6 0.0 1.3 5.6 1.7 0.0 11.8 0.1 0.4 7.3 1.8 1.3 0.1 23.3 7.2 7.1 9.8 0.4 1.1 31.7 13.0 3.7 15.3 16.4 25.4 7.8 23.5 5.5 4.3 9.0 20.2 17.2 1.6 13.5 15.9 14.9 8.0 4.1 7.1 0.0 12.7 19.2 0.3 0.1 3.1 1.0 0.9 21.0 17.2 17.6 22.1 6.3 11.6 25.8 16.6 6.9 26.3 10.1 26.9 12.8 16.0 6.6 16.8 6.0 7.0 5.5 11.3 1.3 4.0 7.7 13.7 4.2 7.3 9.0 18.3 11.8 7.7 16.2 30.6 9.0 24.4 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 1.1 0.1 1.3 0.0 0.0 0.3 0.1 3.8 0.0 0.5 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.4 3.3 0.8 0.8 1.2 34.1 0.1 0.0 1.7 1.0 10.2 3.3 0.0 3.1 0.0 0.0 2.4 0.0 0.0 3.9 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 1.2 0.0 9.7 0.1 0.4 0.2 5.6 0.0 0.0 1.5 0.9 4.0 3.1 10.0 0.3 0.3 2.2 0.5 6.3 0.9 EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9;brain: 16.9" "Group enriched" "Detected in some" 5 "Adipocytes: 29.6;Endothelial cells: 13.1;Fibroblasts: 14.9;Skeletal myocytes: 33.5;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 12.5;HAP1: 13.6;LHCN-M2: 25.4;NB-4: 35.7;RH-30: 13.2;SCLC-21H: 28.7;THP-1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (2.96e-1)" "unprognostic (3.78e-2)" "unprognostic (8.63e-3)" "unprognostic (2.60e-2)" "unprognostic (7.68e-2)" "unprognostic (4.50e-3)" "unprognostic (8.53e-6)" "unprognostic (2.93e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.63e-1)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (9.49e-2)" "unprognostic (4.58e-2)" 23.9 0.6 0.3 1.0 0.1 0.1 13.7 1.4 0.2 4.1 0.4 2.7 0.2 2.3 0.8 1.4 4.8 2.4 9.4 0.1 2.7 0.5 0.5 0.2 6.9 6.5 8.5 1.0 1.3 2.1 0.9 2.5 3.8 2.4 0.5 1.9 3.0 1.1 7.9 3.3 1.0 1.5 16.9 0.2 1.6 1.6 3.2 1.3 7.3 7.7 1.0 3.3 5.5 1.1 0.0 0.0 0.6 0.1 12.5 10.3 0.1 0.8 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 25.4 0.0 0.0 35.7 0.0 0.0 0.0 0.3 13.2 0.0 0.0 0.1 28.7 0.4 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 1.3 8.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.4 0.2 0.1 2.7 6.5 8.5 3.8 16.9 3.2 1.1 29.6 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 1.8 0.3 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 13.1 0.0 0.0 0.9 0.0 0.0 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.5 0.4 0.3 0.4 0.0 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.7 0.0 33.5 11.7 0.0 3.4 0.1 0.9 0.0 0.2 0.1 0.0 0.1 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 EDAR "DL, ED1R, ED3, ED5, EDA1R, EDA3" ENSG00000135960 "Ectodysplasin A receptor" Q9UNE0 2 108894471-108989372 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 3.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.4;Macrophages: 1.1;Squamous epithelial cells: 5.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "naive CD4 T-cell: 7.5;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 75 "T-cells: 7.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.7;HaCaT: 10.2;OE19: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA042292 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA042292: AB_10794648" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (2.22e-2)" "unprognostic (1.24e-2)" "unprognostic (4.68e-2)" "unprognostic (1.21e-2)" "unprognostic (2.30e-1)" "unprognostic (2.53e-2)" "unprognostic (3.70e-1)" "unprognostic (1.31e-1)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (8.83e-7)" "unprognostic (9.21e-2)" "unprognostic (5.61e-2)" "unprognostic (2.29e-1)" "unprognostic (5.03e-3)" 0.0 0.0 0.0 0.9 0.0 0.3 0.2 0.0 0.2 0.6 0.0 1.3 1.1 0.5 0.2 3.6 0.2 0.9 0.0 0.1 0.0 0.6 0.9 0.2 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.7 1.9 0.0 0.6 0.1 0.0 1.4 1.0 0.0 0.0 0.2 0.9 0.1 0.1 1.2 0.0 0.0 1.2 1.5 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.7 0.0 0.4 0.0 0.0 10.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 7.5 3.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.4 0.0 0.1 0.6 0.5 0.0 0.8 0.0 0.0 0.2 0.1 0.1 0.0 0.7 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.8 0.0 0.3 0.8 EEF2K "CaMKIII, eEF-2K" ENSG00000103319 "Eukaryotic elongation factor 2 kinase" O00418 16 22206278-22288738 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 49.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 69.1;Late spermatids: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.5;HL-60: 1.6;HMC-1: 1.8;NB-4: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007818, HPA056061" Approved Approved Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB007818: AB_598150, HPA056061: AB_2683021" "unprognostic (4.79e-2)" "unprognostic (6.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-1)" "unprognostic (1.94e-2)" "unprognostic (5.09e-3)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.74e-1)" "unprognostic (8.50e-2)" "unprognostic (2.01e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" 19.8 7.1 1.0 0.4 0.9 0.7 15.9 1.5 2.2 17.2 0.7 20.1 0.3 14.3 0.7 9.1 13.1 0.3 9.2 0.9 1.2 3.6 7.8 9.0 0.5 1.1 0.9 8.2 12.9 0.0 5.2 0.4 1.2 19.6 0.2 0.3 15.0 0.2 24.9 49.0 8.1 0.3 0.9 8.0 9.8 2.3 1.4 0.0 6.3 0.0 0.2 18.8 15.4 1.1 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 1.5 0.2 0.0 0.0 0.1 0.0 0.6 0.2 1.0 0.0 1.6 1.8 0.0 0.4 0.1 0.1 0.3 0.1 0.1 0.2 1.3 0.0 0.0 0.1 1.6 0.1 0.4 0.0 0.4 1.0 0.2 0.4 0.0 0.3 0.6 0.0 0.0 0.2 0.1 0.2 0.5 0.5 0.7 0.3 1.4 0.0 0.3 0.1 0.3 1.0 1.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.4 0.1 0.0 1.0 0.9 1.5 2.2 0.9 1.2 1.1 0.9 1.2 0.9 1.4 1.1 43.7 22.4 13.3 22.5 7.3 12.6 9.6 3.9 31.3 69.1 15.4 9.3 17.3 12.8 9.8 9.2 14.6 16.3 12.7 24.2 0.0 4.9 42.9 42.4 12.6 18.4 3.0 7.6 21.2 13.4 11.7 19.2 26.0 34.9 29.2 12.0 22.5 17.7 18.7 1.7 37.4 12.3 4.1 15.3 16.2 76.6 14.3 8.7 8.8 15.9 7.9 6.1 6.2 31.7 8.6 10.2 26.3 15.8 19.6 6.6 12.5 4.0 14.9 21.6 6.6 43.5 10.0 1.3 4.2 16.9 23.0 7.8 7.8 5.7 8.1 6.7 EGF ENSG00000138798 "Epidermal growth factor" P01133 4 109912883-110013766 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 110.2;pancreas: 89.5;skeletal muscle: 29.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 12.9;Breast myoepithelial cells: 8.1;Cardiomyocytes: 8.2;Distal tubular cells: 7.9;Excitatory neurons: 8.5;Inhibitory neurons: 11.2;Muller glia cells: 26.2;Skeletal myocytes: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.4;SK-BR-3: 11.6;U-251 MG: 3.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 209000 680000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (2.83e-2)" "unprognostic (1.02e-2)" "unprognostic (8.50e-3)" "unprognostic (1.88e-3)" "unprognostic (4.24e-2)" "unprognostic (1.64e-3)" "unprognostic (5.06e-4)" "unprognostic (8.30e-2)" "unprognostic (2.21e-3)" "unprognostic (4.25e-2)" "unprognostic (1.80e-2)" "unprognostic (2.95e-1)" "unprognostic (7.72e-3)" "unprognostic (4.64e-5)" "unprognostic (2.63e-1)" "unprognostic (9.80e-5)" "unprognostic (3.92e-3)" 0.0 0.0 1.0 0.1 1.0 0.2 14.7 0.2 0.8 0.0 0.2 0.8 0.0 0.4 2.4 0.7 0.3 1.0 2.8 0.9 2.0 110.2 0.0 0.5 0.0 1.4 0.9 0.0 89.5 0.2 0.4 0.0 1.5 1.4 1.1 13.6 15.7 0.4 29.6 0.7 0.2 0.5 1.2 0.1 0.0 0.1 0.7 0.0 3.0 17.4 0.0 0.4 0.1 1.8 0.2 0.2 1.9 0.0 0.0 0.1 0.0 0.4 1.1 0.5 0.4 0.1 0.0 0.0 6.4 0.6 1.6 0.0 0.3 0.0 0.4 0.0 0.3 0.1 0.6 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 1.3 0.1 0.6 0.1 0.0 0.0 2.3 0.0 0.4 0.1 0.1 0.5 0.4 0.2 0.0 0.0 0.0 11.6 0.4 1.2 2.8 0.0 0.0 0.9 1.3 0.0 3.6 0.0 0.0 0.0 1.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.0 1.0 0.2 0.8 0.9 2.0 1.4 0.9 1.5 1.2 0.7 1.8 0.1 0.0 0.0 3.3 0.0 1.0 0.2 0.1 0.0 1.0 12.9 8.1 8.2 0.0 0.5 0.0 0.0 0.0 0.2 2.0 7.9 0.2 5.6 0.2 0.1 0.6 0.0 0.0 8.5 5.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.7 11.2 0.1 0.0 0.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 26.2 0.0 1.5 0.3 1.0 0.4 0.0 0.0 1.1 0.1 1.2 1.0 1.2 0.0 8.2 0.2 0.5 0.4 0.0 1.4 0.0 0.1 0.1 1.6 0.3 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EGLN2 "HIFPH1, PHD1" ENSG00000269858 "Egl-9 family hypoxia inducible factor 2" Q96KS0 19 40798996-40808434 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 269.1;Late spermatids: 740.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056649 Supported Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA056649: AB_2683203" "unprognostic (1.11e-2)" "prognostic favorable (2.88e-4)" "unprognostic (9.40e-3)" "unprognostic (6.01e-2)" "unprognostic (6.03e-2)" "unprognostic (6.47e-3)" "unprognostic (1.51e-2)" "unprognostic (4.74e-2)" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.81e-4)" "unprognostic (7.10e-2)" "unprognostic (7.48e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (9.99e-2)" "unprognostic (1.38e-3)" 57.6 58.5 99.3 50.0 99.8 52.1 47.6 95.1 140.9 70.0 79.6 65.4 34.3 53.9 31.5 40.2 45.5 39.1 67.8 103.4 96.2 54.2 57.7 74.3 62.4 97.3 99.3 59.0 36.6 27.7 44.5 48.3 97.7 59.9 28.5 16.6 39.2 45.1 40.0 27.4 46.7 40.9 90.5 116.8 47.6 232.1 99.9 41.9 55.8 40.8 44.1 57.9 57.9 98.1 46.5 123.4 55.9 54.4 71.1 51.5 36.5 49.4 41.1 68.9 75.4 102.8 45.7 41.1 41.1 59.3 62.5 29.3 70.8 56.3 36.4 51.7 40.5 54.8 76.4 39.4 76.1 42.7 71.6 63.9 58.5 65.8 37.4 43.3 86.0 44.3 79.3 37.3 73.4 32.9 78.9 70.2 48.7 72.4 42.6 72.7 27.7 27.8 74.0 70.2 51.4 46.9 80.9 62.9 67.2 47.2 83.4 114.0 80.5 85.9 61.7 35.7 59.5 18.7 29.6 75.6 63.0 61.4 65.5 93.2 72.5 190.5 85.8 83.4 91.1 85.2 101.7 90.3 62.6 90.0 105.2 89.6 261.6 61.4 82.3 45.5 100.2 110.5 99.3 99.8 95.1 140.9 103.4 96.2 97.3 99.3 97.7 90.5 99.9 98.1 2.8 22.4 16.8 0.0 43.9 48.8 55.2 33.8 17.6 40.5 3.3 0.8 22.2 31.5 30.7 3.7 14.6 58.1 19.0 83.0 0.0 15.8 269.1 0.9 1.5 49.9 44.9 30.7 0.0 10.1 26.5 27.6 23.9 1.2 17.2 0.8 72.8 33.7 66.7 21.9 0.0 33.9 48.8 39.8 62.4 740.8 63.0 26.3 40.9 0.0 38.5 24.4 60.8 0.0 0.0 14.0 71.0 52.3 8.7 67.6 54.9 1.4 23.0 17.8 39.5 14.6 17.2 159.4 52.5 14.2 38.4 132.6 33.2 2.1 43.7 69.8 EIF4A3 "DDX48, EIF4AIII, Fal1, KIAA0111" ENSG00000141543 "Eukaryotic translation initiation factor 4A3" P38919 17 80134369-80147151 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, rRNA processing, Translation regulation, Transport" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021878 Supported Supported Nucleoplasm NA NA 280000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA021878: AB_1848090" "unprognostic (7.24e-2)" "unprognostic (7.33e-3)" "prognostic favorable (3.57e-5)" "unprognostic (1.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.68e-5)" "prognostic unfavorable (1.87e-4)" "unprognostic (3.71e-1)" "unprognostic (5.06e-2)" "unprognostic (4.64e-2)" "unprognostic (2.64e-2)" "unprognostic (9.78e-3)" "unprognostic (5.81e-2)" "unprognostic (9.20e-2)" "unprognostic (1.38e-2)" "unprognostic (2.91e-3)" 65.8 81.4 19.0 49.1 21.1 185.8 44.2 21.5 27.2 51.2 22.8 44.3 38.6 46.6 38.8 81.9 54.7 40.1 38.0 22.3 21.0 45.1 42.6 44.0 67.0 19.9 19.5 66.5 37.0 58.5 41.1 52.9 20.3 38.7 47.5 32.3 42.4 32.6 37.3 64.8 38.9 42.6 22.7 47.6 41.4 42.8 20.0 78.2 37.0 34.9 74.7 83.4 55.1 24.7 237.2 208.9 140.5 103.8 105.5 63.2 114.4 119.3 91.0 177.7 141.4 223.7 110.3 221.4 67.9 112.9 126.4 152.2 194.9 136.2 195.0 71.5 192.3 142.5 159.3 244.3 103.1 253.8 133.4 98.7 68.7 149.5 119.4 71.8 147.2 128.7 189.8 140.2 105.3 178.9 224.8 132.8 145.0 223.8 190.0 168.5 282.7 172.2 85.8 196.5 186.1 100.1 170.9 334.2 151.9 130.1 219.3 166.7 100.5 108.7 138.6 159.9 200.3 104.4 86.2 403.2 88.0 158.7 113.3 126.1 167.0 137.4 101.1 174.6 131.2 142.4 128.2 119.4 200.0 119.8 116.9 115.2 98.7 132.9 143.4 326.0 158.2 232.6 19.0 21.1 21.5 27.2 22.3 21.0 19.9 19.5 20.3 22.7 20.0 24.7 117.9 41.7 48.0 6.8 135.1 283.1 273.4 212.9 107.0 23.3 77.0 109.2 61.5 38.6 107.8 29.5 16.7 140.1 165.7 75.4 64.6 85.6 33.2 132.9 109.2 70.5 60.3 24.4 4.1 115.2 225.1 144.3 149.4 248.2 92.6 42.6 32.2 27.0 108.5 6.7 4.3 83.2 89.5 63.4 255.0 12.1 67.1 199.6 103.2 10.3 67.9 48.6 23.7 5.5 7.6 86.6 83.1 49.7 118.6 96.0 47.9 65.0 61.4 32.5 85.5 109.7 207.8 99.4 123.2 77.6 299.1 261.9 138.4 98.0 77.7 252.5 EIF4ENIF1 "2610509L04Rik, 4E-T, Clast4, FLJ21601" ENSG00000184708 "Eukaryotic translation initiation factor 4E nuclear import factor 1" Q9NRA8 22 31436977-31496108 "Plasma proteins, Predicted intracellular proteins" "Protein transport, RNA-mediated gene silencing, Translation regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 54.6;Late spermatids: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001619, HPA002078" Enhanced Enhanced Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA001619: AB_1078727, HPA002078: AB_1078728" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" "unprognostic (3.01e-2)" "unprognostic (1.53e-1)" "unprognostic (6.72e-2)" "unprognostic (2.28e-3)" "unprognostic (1.30e-2)" "unprognostic (4.95e-2)" "unprognostic (9.92e-2)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "prognostic favorable (1.57e-4)" "unprognostic (2.30e-1)" "unprognostic (1.92e-1)" "unprognostic (7.32e-2)" "unprognostic (2.45e-2)" 12.5 11.9 14.3 10.4 14.8 14.3 11.9 19.7 17.3 15.9 11.4 19.4 11.4 15.0 13.0 14.0 13.8 7.8 13.2 15.3 15.0 12.3 8.4 12.1 12.6 13.6 14.7 15.0 10.5 16.7 10.8 13.6 14.3 13.5 11.5 18.0 12.1 13.2 20.2 15.7 11.8 12.1 11.6 12.3 12.3 34.7 13.8 12.9 13.5 14.5 14.9 15.6 14.3 17.3 19.8 11.6 29.4 16.0 16.1 14.2 11.7 13.7 16.8 21.4 19.8 13.4 7.0 25.3 7.9 20.7 14.3 19.1 26.9 12.5 19.7 20.2 27.0 10.3 20.0 15.4 16.7 41.0 17.9 16.6 16.9 15.8 17.8 19.5 18.4 14.8 25.4 27.0 20.3 22.4 27.8 20.3 13.5 18.3 9.5 31.1 24.5 26.0 21.7 14.7 22.6 20.9 18.9 15.4 14.5 19.4 16.4 16.1 20.5 14.3 18.6 14.4 15.5 19.3 20.4 25.1 13.7 14.8 17.1 1.3 2.4 1.2 3.4 3.0 3.5 4.8 1.8 3.3 2.2 2.0 1.8 3.2 2.0 1.0 8.1 4.4 1.4 1.9 14.3 14.8 19.7 17.3 15.3 15.0 13.6 14.7 14.3 11.6 13.8 17.3 8.4 12.8 15.2 23.2 10.6 7.4 7.3 6.2 15.4 18.0 9.6 8.9 22.7 10.0 8.5 12.9 12.5 9.8 13.8 8.6 9.8 8.9 54.6 8.0 12.8 10.2 12.0 12.4 21.0 6.4 5.5 8.1 12.2 13.0 6.3 23.1 11.0 8.9 8.0 18.5 20.5 10.8 8.2 9.5 6.2 98.9 14.6 7.5 7.2 13.1 14.5 8.1 14.4 20.1 20.2 10.2 3.6 15.4 10.3 10.7 5.7 9.4 6.3 13.7 6.6 11.8 11.0 38.7 13.3 10.7 10.5 6.7 8.2 9.0 8.1 8.0 EIF4G1 "EIF4F, EIF4G, p220, PARK18" ENSG00000114867 "Eukaryotic translation initiation factor 4 gamma 1" Q04637 3 184314495-184335358 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding, Translational shunt" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 348.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014774, HPA028487, HPA043866" Approved Enhanced Cytosol NA NA 330000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB014774: , HPA028487: AB_10602219, HPA043866: AB_2678705" "unprognostic (4.14e-3)" "unprognostic (2.10e-2)" "unprognostic (6.01e-2)" "unprognostic (3.01e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (4.27e-3)" "unprognostic (2.35e-1)" "unprognostic (1.54e-1)" "unprognostic (1.55e-3)" "unprognostic (7.06e-3)" "unprognostic (2.42e-1)" "unprognostic (7.15e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-1)" "unprognostic (2.33e-3)" 86.2 91.8 24.8 75.7 22.2 84.0 69.0 17.9 22.2 66.6 34.1 81.8 62.0 71.3 32.7 126.8 59.6 50.9 90.8 23.3 29.8 53.9 113.0 74.2 55.7 38.5 36.1 57.5 96.2 99.3 57.4 59.4 32.4 62.2 56.5 22.3 93.1 59.2 348.3 116.7 67.2 74.7 24.4 58.2 79.9 64.8 37.4 49.1 71.3 177.0 63.2 76.0 85.3 16.6 559.0 232.3 173.1 205.7 196.9 192.5 322.5 298.6 204.1 315.4 238.8 486.5 173.7 348.4 381.9 367.6 358.5 292.7 322.6 365.8 230.5 375.1 345.8 321.3 226.1 206.4 173.4 321.4 212.2 199.6 206.8 292.4 268.8 152.8 278.3 128.8 239.6 267.2 205.7 403.4 219.7 105.3 368.9 241.3 180.8 221.7 183.4 281.9 156.8 331.8 197.7 174.6 258.1 415.6 187.6 144.6 445.2 206.5 364.1 227.2 228.9 297.3 567.9 203.8 263.2 629.0 260.5 271.4 258.3 8.3 16.0 6.7 11.7 14.4 10.8 7.7 7.8 9.6 12.8 9.2 6.9 7.6 5.6 8.7 21.0 18.1 6.0 12.7 24.8 22.2 17.9 22.2 23.3 29.8 38.5 36.1 32.4 24.4 37.4 16.6 63.9 76.9 72.6 23.8 41.7 59.1 78.2 58.0 70.6 24.2 69.3 46.2 109.4 50.1 72.3 62.5 14.6 64.0 37.6 135.5 13.7 98.8 151.6 53.0 67.1 69.3 55.7 82.7 10.8 135.3 74.8 64.5 75.4 85.6 48.0 163.8 43.5 152.8 66.8 21.9 12.9 97.2 50.8 40.8 39.9 202.7 73.0 48.9 33.8 14.0 53.0 23.2 30.9 4.0 10.1 149.0 69.0 56.1 112.9 96.8 77.0 45.4 51.4 23.2 78.9 81.6 78.9 24.8 41.4 120.7 91.8 79.6 46.0 94.8 108.4 95.6 EIF4H "KIAA0038, WBSCR1, WSCR1" ENSG00000106682 "Eukaryotic translation initiation factor 4H" Q15056 7 74174231-74197122 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 990.0;Late spermatids: 2765.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030542 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 750000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Nuclear bodies" "HPA030542: AB_10601368" "unprognostic (2.83e-1)" "unprognostic (9.50e-2)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (3.89e-4)" "prognostic unfavorable (2.15e-4)" "unprognostic (1.61e-2)" "unprognostic (2.72e-3)" "unprognostic (1.79e-1)" "unprognostic (2.99e-2)" "unprognostic (1.72e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-2)" "unprognostic (3.04e-1)" "unprognostic (2.23e-1)" "unprognostic (5.68e-2)" "unprognostic (1.27e-2)" 186.9 174.9 151.0 117.8 159.3 283.3 168.3 163.8 157.3 179.8 129.6 208.4 130.2 186.4 76.6 249.3 163.6 100.0 171.0 149.9 151.9 156.6 197.0 158.4 130.3 161.9 156.9 181.2 226.4 160.7 119.9 162.8 162.2 150.3 100.2 149.8 170.1 125.1 399.8 230.9 148.9 119.2 165.2 137.4 192.9 79.9 164.6 150.2 141.2 173.4 137.2 175.3 179.7 187.1 526.3 341.4 251.3 303.1 220.8 231.8 283.4 359.8 276.3 300.3 289.5 423.3 388.6 444.3 96.6 338.8 424.2 266.6 280.5 481.5 286.3 298.0 329.2 247.5 305.2 345.9 253.1 429.0 236.9 273.2 300.8 326.2 460.7 341.5 326.8 260.1 445.8 186.4 305.2 448.2 342.0 516.8 337.6 430.3 328.9 386.9 342.7 401.5 250.9 324.7 252.7 325.4 340.9 420.3 296.0 331.3 476.8 272.4 340.2 411.6 284.6 345.1 474.4 218.8 299.8 771.4 326.3 435.1 441.4 213.7 229.7 245.6 156.9 255.6 164.5 146.4 161.4 158.3 224.2 132.9 183.9 151.7 150.1 193.5 270.2 95.1 194.7 388.0 151.0 159.3 163.8 157.3 149.9 151.9 161.9 156.9 162.2 165.2 164.6 187.1 105.8 83.3 81.2 15.7 97.1 119.2 153.8 101.5 78.0 93.1 103.0 95.5 43.3 68.6 68.7 44.1 25.0 198.8 91.9 98.7 107.6 148.1 990.0 104.8 98.3 103.0 90.4 79.5 25.3 157.7 381.4 101.6 61.2 112.5 122.4 112.1 79.6 95.7 124.2 97.6 24.6 87.2 91.6 101.2 102.7 2765.8 103.8 86.8 72.9 15.9 157.4 134.7 119.4 16.6 44.2 147.0 82.8 110.6 82.7 140.7 84.6 69.0 57.8 72.3 85.5 107.3 117.7 61.2 64.6 90.1 116.1 395.3 92.4 116.9 109.5 140.4 ELAVL2 "HEL-N1, HuB" ENSG00000107105 "ELAV like RNA binding protein 2" Q12926 9 23690104-23826337 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 31.8;testis: 43.1" "Cell type enhanced" "Detected in many" "Early spermatids: 62.2;Excitatory neurons: 135.5;Inhibitory neurons: 390.6;Spermatogonia: 159.2" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 25.4;AF22: 37.2;SCLC-21H: 119.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022222, HPA063001" Enhanced Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "CAB022222: , HPA063001: AB_2684918" "unprognostic (3.51e-1)" "unprognostic (4.18e-2)" "unprognostic (2.05e-1)" "unprognostic (1.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-1)" "unprognostic (4.26e-2)" "unprognostic (8.94e-2)" "unprognostic (3.23e-1)" "unprognostic (1.01e-1)" "unprognostic (9.74e-4)" "unprognostic (3.98e-1)" "unprognostic (9.08e-4)" "unprognostic (8.30e-2)" "unprognostic (1.91e-2)" "unprognostic (2.12e-1)" "unprognostic (2.65e-1)" 0.1 1.3 12.4 0.1 15.8 0.5 0.2 1.5 31.8 0.1 0.0 0.4 0.1 0.5 0.5 0.2 0.1 0.2 0.1 10.9 23.2 0.5 0.0 0.2 0.2 15.7 13.0 1.1 0.0 0.1 1.0 0.1 15.3 0.3 0.5 5.0 0.1 0.1 0.1 0.5 0.2 0.2 0.1 0.1 0.1 43.1 15.0 0.0 0.3 0.0 0.1 0.4 0.2 9.4 25.4 0.3 37.2 0.2 0.1 0.3 0.1 0.3 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 7.8 9.9 15.9 0.2 0.0 7.1 0.0 0.1 0.3 0.0 0.2 0.6 0.5 9.6 0.0 11.0 0.0 0.3 0.1 0.9 1.2 5.3 0.0 0.1 0.1 9.8 0.0 11.8 0.1 13.3 0.2 0.0 0.0 119.6 11.5 0.3 0.3 0.3 9.4 0.6 1.9 0.0 0.2 7.9 0.2 0.2 0.1 0.1 0.1 1.3 0.1 1.4 1.1 0.3 0.5 0.1 0.2 0.2 0.3 0.1 0.1 0.1 0.5 0.3 0.4 1.5 0.4 0.2 0.3 0.2 0.0 12.4 15.8 1.5 31.8 10.9 23.2 15.7 13.0 15.3 0.1 15.0 9.4 0.9 0.0 0.0 7.8 0.0 1.0 0.4 0.4 0.6 8.8 0.9 0.6 0.9 0.0 0.1 0.0 0.0 0.0 0.0 1.4 1.9 0.1 62.2 0.5 0.2 1.8 4.2 0.0 135.5 0.0 0.0 0.8 0.0 0.2 0.0 10.6 0.0 0.0 0.1 16.8 390.6 1.2 0.0 0.0 0.7 39.5 3.1 0.2 0.0 7.5 0.0 2.8 0.0 5.5 5.5 0.0 0.2 1.5 0.0 0.4 0.0 0.1 0.0 10.6 0.0 1.4 1.0 13.9 159.2 0.5 0.9 0.0 0.1 0.7 1.3 0.6 ELF5 ENSG00000135374 "E74 like ETS transcription factor 5" Q9UKW6 11 34478791-34525193 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 151.2;salivary gland: 147.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 40.3;Breast glandular cells: 143.2;Breast myoepithelial cells: 57.1;Collecting duct cells: 101.2;Cytotrophoblasts: 26.9" "Cancer enhanced" "Detected in many" "breast cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "RT4: 30.2;T-47d: 56.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062706 Approved Nucleoplasm NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "HPA062706: AB_2684841" "unprognostic (1.13e-1)" "unprognostic (1.48e-1)" "unprognostic (7.55e-2)" "unprognostic (3.31e-2)" "unprognostic (2.41e-4)" "unprognostic (6.90e-2)" "unprognostic (3.93e-1)" "prognostic favorable (3.64e-4)" "unprognostic (1.12e-1)" "unprognostic (3.40e-2)" "unprognostic (8.15e-2)" "unprognostic (3.15e-2)" "unprognostic (1.78e-3)" "unprognostic (3.09e-1)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (2.86e-1)" 0.2 0.0 0.1 0.0 0.1 0.2 151.2 0.2 0.2 0.9 0.4 0.0 2.1 0.0 0.0 1.3 0.1 0.2 0.0 0.1 0.0 17.0 0.2 7.5 0.0 0.0 0.1 0.0 0.5 0.0 0.0 1.4 0.0 2.5 0.0 0.0 147.6 30.4 0.0 6.2 0.0 0.0 0.0 1.1 0.6 0.2 0.1 0.5 0.0 0.0 2.5 5.7 2.3 0.2 0.1 0.0 0.0 0.1 0.0 0.5 3.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 30.2 0.0 0.0 0.0 5.1 0.0 0.1 56.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 1.0 3.2 40.3 0.0 1.1 0.3 1.9 0.9 0.0 0.0 143.2 57.1 0.4 0.0 9.7 101.2 0.0 26.9 1.4 0.0 0.0 0.0 0.2 0.1 0.1 0.8 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 2.0 1.9 0.4 0.1 0.0 0.5 17.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.4 4.8 0.0 0.0 0.2 0.9 2.5 0.2 0.0 0.1 11.5 0.6 0.0 0.0 6.5 ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.7;skin 1: 25.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.2;Gastric mucus-secreting cells: 4.6;Proximal enterocytes: 6.5;Squamous epithelial cells: 21.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 10.5;naive B-cell: 15.9" "Lineage enriched" "Detected in many" 7 "B-cells: 15.9" "Cell line enhanced" "Detected in many" "Daudi: 73.8;OE19: 28.5;T-47d: 39.0;U-698: 149.9" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: AB_10795352, HPA073494: " "unprognostic (2.59e-2)" "unprognostic (4.41e-1)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-3)" "unprognostic (1.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.87e-1)" "unprognostic (3.67e-2)" "unprognostic (8.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-2)" 0.5 0.9 1.0 9.7 1.0 0.2 5.2 1.0 1.1 1.6 4.7 8.0 14.1 0.6 1.1 4.5 3.9 0.7 0.5 1.0 1.1 1.4 0.7 1.5 49.7 1.0 1.1 1.7 0.4 1.6 0.5 3.7 1.1 2.0 12.3 0.1 2.2 1.0 0.4 25.0 12.9 1.0 1.0 1.0 1.8 16.2 1.4 1.5 0.7 1.9 57.7 0.7 0.8 1.1 2.1 0.2 0.6 1.1 4.9 1.2 0.4 0.2 1.3 2.8 3.1 0.0 1.3 73.8 0.1 1.2 0.1 13.7 1.3 0.7 1.4 1.6 7.3 0.4 2.6 4.6 1.0 0.1 0.0 1.4 12.3 0.7 0.2 0.2 1.1 0.4 0.2 0.0 0.7 4.0 1.5 1.4 0.1 28.5 2.4 0.8 0.0 0.0 1.8 0.0 9.5 0.0 1.7 21.5 0.0 0.3 39.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 149.9 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 10.5 0.6 0.1 0.0 15.9 1.1 0.2 0.0 0.1 0.0 2.2 0.6 0.6 1.0 1.0 1.0 1.1 1.0 1.1 1.0 1.1 1.1 1.0 1.4 1.1 0.1 0.0 0.0 0.0 2.2 0.4 0.1 0.2 5.2 0.0 0.7 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.3 1.2 0.0 0.1 1.8 0.4 0.1 0.2 0.0 0.4 0.1 0.7 0.0 0.5 4.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.5 0.0 0.0 0.5 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 6.5 0.1 3.1 0.0 0.0 0.2 0.4 0.2 0.2 21.0 1.0 0.3 0.1 0.1 2.3 0.2 ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 70.4;Fibroblasts: 115.9;Leydig cells: 110.6;Peritubular cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 97.6;BJ: 143.7;fHDF/TERT166: 205.6;U-2197: 817.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" 147.2 21.6 11.6 40.8 14.3 0.1 94.2 19.9 17.6 100.2 24.3 57.6 8.8 73.6 18.4 53.0 70.7 76.7 184.1 13.1 15.3 12.8 13.4 214.1 14.5 15.4 20.1 37.0 90.9 2.8 24.9 58.9 13.8 106.4 11.3 2.8 66.9 35.1 17.9 91.3 40.6 90.0 14.9 40.9 63.2 13.1 14.0 5.1 48.4 16.9 4.5 85.3 84.3 17.9 0.0 2.0 0.8 0.0 97.6 0.6 0.6 143.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 205.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.6 0.6 8.3 0.8 0.8 0.4 58.0 1.0 0.0 0.0 28.0 68.9 0.0 1.2 0.1 10.0 0.6 0.0 0.0 0.2 0.3 817.9 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 14.3 19.9 17.6 13.1 15.3 15.4 20.1 13.8 14.9 14.0 17.9 34.6 0.0 6.4 34.9 0.1 11.0 13.5 33.9 4.0 2.8 0.9 1.1 9.7 2.8 4.3 7.3 2.1 0.1 0.3 0.2 0.0 0.3 3.5 3.5 70.4 28.4 1.8 0.0 4.6 3.9 0.3 115.9 7.1 2.3 0.0 0.2 47.2 4.2 0.5 6.7 8.1 1.3 0.0 0.6 20.4 7.5 110.6 1.2 14.2 23.4 0.0 15.9 0.0 14.1 18.5 1.1 0.2 148.2 0.4 1.4 0.0 0.1 3.0 0.8 0.0 12.2 34.1 1.1 1.2 2.1 10.9 0.1 1.2 0.6 0.2 1.1 ELOVL7 FLJ23563 ENSG00000164181 "ELOVL fatty acid elongase 7" A1L3X0 5 60751791-60844274 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 190.2;Oligodendrocytes: 90.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.9;neutrophil: 1.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "GAMG: 41.9;HDLM-2: 29.3;HEL: 37.3" "Low region specificity" "Detected in all" HPA036337 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "HPA036337: AB_10670797" "unprognostic (6.34e-2)" "unprognostic (1.96e-2)" "unprognostic (1.51e-2)" "prognostic unfavorable (3.87e-5)" "unprognostic (3.84e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.54e-9)" "unprognostic (6.95e-2)" "unprognostic (1.01e-3)" "unprognostic (2.94e-1)" "unprognostic (6.30e-3)" 10.5 5.5 23.1 2.2 24.9 1.0 22.1 29.5 26.5 3.6 36.2 8.8 11.8 2.2 0.9 5.0 2.8 19.3 0.9 18.3 30.0 16.2 1.0 3.8 2.5 31.8 26.3 0.5 8.5 21.0 2.7 0.8 32.9 22.0 11.5 10.5 4.7 1.2 0.5 26.2 21.3 3.7 30.1 0.5 3.3 0.8 32.9 1.8 16.8 1.0 4.0 7.6 6.7 32.2 20.7 7.6 0.1 0.5 0.0 0.0 18.6 0.0 4.3 2.5 8.4 9.6 21.4 0.0 9.1 0.0 41.9 1.2 11.9 8.3 3.8 29.3 6.9 37.3 0.9 3.2 0.2 3.0 15.2 0.1 14.6 0.3 12.3 0.9 0.0 6.5 5.9 7.2 0.0 17.8 0.1 0.3 2.4 1.9 0.1 1.6 1.9 1.2 19.4 18.5 7.8 1.2 10.9 8.8 5.0 2.0 14.2 0.6 0.2 1.5 9.0 0.2 7.2 18.5 19.7 0.3 13.2 0.8 0.4 1.9 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 2.5 23.1 24.9 29.5 26.5 18.3 30.0 31.8 26.3 32.9 30.1 32.9 32.2 14.5 12.8 3.1 4.9 0.5 31.1 13.1 1.4 4.6 2.3 3.1 1.4 0.7 20.0 4.8 12.9 0.0 0.2 0.3 8.8 5.9 6.8 0.1 6.5 1.6 21.1 4.8 1.3 29.5 3.1 0.0 2.0 5.6 20.4 12.7 0.4 0.4 0.0 0.1 0.0 26.0 17.0 0.0 0.0 16.6 0.0 0.0 4.9 10.6 190.2 2.0 3.5 0.0 6.0 90.8 7.1 13.3 0.0 0.1 23.4 29.7 8.9 1.7 6.7 0.0 1.0 0.8 0.2 1.1 2.9 38.2 2.9 0.9 0.2 15.9 8.6 EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Adipocytes: 409.0;Endothelial cells: 261.7;Hepatic stellate cells: 175.3;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" NA NA 470000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" 46.3 20.2 6.7 9.6 7.1 0.2 38.2 7.1 11.2 37.1 7.8 10.3 6.8 27.9 9.9 12.7 19.2 31.4 38.5 6.3 7.5 79.7 7.5 48.4 6.6 8.1 7.0 6.9 6.2 19.2 9.6 0.8 9.0 12.7 8.1 1.5 9.2 25.6 18.5 9.0 8.3 38.8 7.0 3.5 8.2 2.3 9.4 8.7 43.6 40.2 4.9 24.9 13.9 7.4 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.0 30.6 0.0 0.0 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 7.1 7.1 11.2 6.3 7.5 8.1 7.0 9.0 7.0 9.4 7.4 409.0 6.4 6.0 0.3 14.0 16.6 0.5 0.1 6.2 0.1 2.1 3.0 14.1 0.0 0.7 0.0 0.0 0.1 1.7 0.0 0.0 0.1 0.7 0.6 0.6 261.7 0.0 8.0 1.3 0.0 0.0 16.2 0.0 0.3 0.0 0.1 175.3 1.1 0.2 0.0 0.2 0.0 0.0 5.5 21.4 1.3 1.2 1.7 16.0 111.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 2.6 1.0 0.0 0.2 0.0 0.4 0.0 5.8 21.4 0.2 0.5 1.1 14.6 0.3 2.4 0.7 0.0 1.0 EME1 "FLJ31364, MMS4L, SLX2A" ENSG00000154920 "Essential meiotic structure-specific endonuclease 1" Q96AY2 17 50373220-50381483 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.4;epididymis: 6.3;testis: 5.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.6;Extravillous trophoblasts: 4.8;Granulosa cells: 4.5;Spermatocytes: 13.2;Spermatogonia: 9.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "basophil: 18.6" "Lineage enriched" "Detected in single" 33 "granulocytes: 18.6" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016127, HPA052188" Supported Approved "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Cytosol" "CAB016127: AB_2278026, HPA052188: " "unprognostic (3.81e-1)" "unprognostic (7.72e-2)" "unprognostic (6.49e-2)" "unprognostic (2.45e-3)" "unprognostic (2.74e-1)" "unprognostic (1.94e-2)" "unprognostic (9.94e-5)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.02e-2)" "unprognostic (4.37e-3)" "unprognostic (2.83e-3)" "unprognostic (0.00e+0)" "unprognostic (9.82e-2)" "unprognostic (1.26e-1)" "unprognostic (3.71e-1)" "unprognostic (3.41e-1)" 0.5 0.3 0.2 1.7 0.3 4.4 0.6 0.1 0.4 0.5 0.0 0.9 0.8 0.4 6.3 1.1 0.3 0.3 0.2 0.1 0.1 0.2 0.4 0.4 2.3 0.3 0.2 0.5 0.2 0.1 0.1 1.4 0.3 0.2 1.3 0.4 0.5 0.1 0.2 1.1 0.7 0.6 0.1 0.9 0.5 5.7 0.3 3.3 0.2 0.0 2.6 0.4 0.5 0.4 13.9 20.0 26.2 13.7 1.2 2.6 18.8 14.2 5.4 19.3 17.7 31.7 11.0 11.0 18.3 5.7 12.0 10.7 24.5 11.3 27.3 21.7 19.3 26.3 23.3 14.8 0.1 10.9 8.4 0.5 0.8 22.3 9.2 2.6 4.5 31.2 16.3 25.6 11.6 15.2 25.0 13.9 15.1 14.2 13.6 25.5 50.7 15.4 4.3 5.6 10.1 20.2 8.7 4.8 8.1 20.9 16.8 12.3 3.1 24.8 14.9 16.6 19.7 16.0 17.4 10.5 7.8 12.2 15.6 18.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.3 0.1 0.4 0.1 0.1 0.3 0.2 0.3 0.1 0.3 0.4 0.1 0.0 1.1 0.3 0.8 0.1 0.3 0.5 0.6 1.5 0.5 0.3 0.4 0.0 0.7 0.0 0.0 4.6 0.5 0.6 0.0 0.3 0.5 0.8 0.7 0.4 0.0 3.8 0.1 0.0 4.8 0.8 2.0 0.5 0.0 4.5 0.0 0.3 2.2 0.0 0.1 0.9 0.0 0.0 1.4 0.6 0.6 0.8 0.0 0.0 1.0 0.5 1.0 0.0 0.3 0.1 0.0 0.0 2.5 0.1 0.1 0.0 0.9 0.3 0.0 0.6 1.0 13.2 9.1 1.5 0.1 1.1 0.5 0.6 1.3 0.2 EMID1 "EMI5, EMU1, hEmu1" ENSG00000186998 "EMI domain containing 1" Q96A84 22 29205896-29259597 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.5;lymphoid tissue: 54.8" "Cell type enhanced" "Detected in many" "Astrocytes: 92.1;Granulosa cells: 32.7;Oligodendrocyte precursor cells: 51.8;Theca cells: 151.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 23.1;glioma: 7.8;ovarian cancer: 10.9;thyroid cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HEL: 28.8;NB-4: 102.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000592 Uncertain "Secreted in other tissues" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "HPA000592: AB_1078737" "unprognostic (2.20e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-2)" "unprognostic (7.80e-3)" "unprognostic (2.40e-2)" "unprognostic (1.42e-1)" "unprognostic (3.46e-1)" "unprognostic (6.25e-3)" "unprognostic (3.75e-2)" "unprognostic (2.33e-1)" "unprognostic (5.24e-3)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "unprognostic (3.09e-2)" "unprognostic (1.08e-1)" 2.6 29.0 34.5 4.2 35.0 14.8 2.5 27.7 49.5 6.5 24.4 5.7 5.1 10.0 1.7 1.3 10.4 4.8 2.3 36.8 29.4 15.0 3.3 13.0 7.5 30.1 30.4 7.0 14.0 12.4 2.0 4.9 28.3 6.1 3.4 0.3 3.6 3.9 0.8 6.3 8.3 2.3 27.0 54.8 7.7 2.3 27.8 4.8 13.2 0.3 2.3 4.9 2.2 32.4 0.0 0.2 4.9 10.5 0.0 0.0 0.7 0.0 0.0 0.4 0.3 5.7 0.7 0.0 4.7 0.1 0.0 0.0 2.5 0.1 0.0 11.5 8.6 28.8 0.1 1.1 0.7 4.1 2.2 0.3 0.2 0.2 0.0 0.0 0.0 6.4 2.5 0.0 0.0 8.0 0.2 102.0 1.1 0.1 0.4 0.0 0.2 11.3 0.0 0.1 13.2 6.3 0.4 0.1 0.2 0.8 4.2 5.4 0.0 0.0 8.0 0.0 0.1 0.5 0.0 0.0 0.0 14.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 34.5 35.0 27.7 49.5 36.8 29.4 30.1 30.4 28.3 27.0 27.8 32.4 0.4 0.0 2.5 92.1 0.1 2.8 1.0 0.1 0.0 1.7 5.3 3.9 0.7 4.3 0.6 0.0 0.0 0.1 0.2 0.0 0.0 1.2 0.2 10.8 22.6 6.2 0.0 18.5 5.6 1.3 0.1 11.8 0.5 20.0 11.4 32.7 11.4 2.1 0.3 0.0 6.2 0.4 0.0 0.3 5.2 0.5 3.1 0.6 0.0 10.3 0.6 1.1 0.0 51.8 1.0 0.4 0.0 1.9 1.0 1.9 0.1 1.9 0.0 0.4 0.0 17.5 4.0 0.1 1.5 0.0 2.0 0.3 1.1 151.0 0.3 0.4 EMILIN2 "FLJ33200, FOAP-10" ENSG00000132205 "Elastin microfibril interfacer 2" Q9BXX0 18 2847006-2916003 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 76.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 98.0;Hofbauer cells: 61.1;Kupffer cells: 52.9;Langerhans cells: 99.7;Macrophages: 97.5;monocytes: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 5.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.2;BEWO: 37.8;HL-60: 37.8;HMC-1: 60.6;HSkMC: 26.1;SuSa: 25.7;THP-1: 36.7;U-2197: 46.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 25.7" HPA064576 Supported "Secreted to extracellular matrix" NA NA 840000 "Cluster 41: Basophils - Cellular respiration" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA064576: AB_2732717" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (7.91e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-3)" "unprognostic (9.91e-3)" "prognostic unfavorable (6.30e-4)" "unprognostic (2.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.49e-1)" "unprognostic (3.15e-3)" "unprognostic (3.72e-2)" "unprognostic (2.96e-1)" 13.0 1.3 1.2 17.2 2.2 11.3 5.1 4.8 1.7 5.3 2.2 2.8 1.6 6.4 0.8 2.4 4.7 5.9 6.8 0.7 1.2 1.1 1.5 11.9 2.4 8.1 4.4 5.9 1.4 76.0 0.4 21.9 5.8 1.0 3.3 0.1 2.3 1.2 0.8 2.7 2.2 8.4 6.6 3.9 1.6 1.8 7.4 2.9 1.6 2.4 2.0 8.0 4.0 10.6 0.2 0.4 2.9 0.0 48.2 19.9 37.8 7.9 0.0 1.4 2.4 5.6 0.1 0.0 0.6 19.3 0.5 0.1 1.0 0.0 2.6 0.0 2.6 0.5 0.2 0.4 1.6 37.8 60.6 26.1 0.0 1.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.1 10.4 4.9 0.4 0.1 0.1 2.5 0.0 0.1 0.2 0.4 0.2 0.2 0.3 1.4 25.7 0.0 36.7 0.4 0.0 5.2 46.7 0.4 0.0 0.0 0.0 3.1 9.1 1.0 5.5 1.1 0.3 0.4 0.8 0.3 0.2 0.4 0.3 1.1 0.3 0.2 0.4 1.1 1.5 0.7 0.7 0.3 0.4 1.2 2.2 4.8 1.7 0.7 1.2 8.1 4.4 5.8 6.6 7.4 10.6 6.8 3.2 6.7 0.0 13.7 5.7 3.3 0.5 0.6 0.1 2.8 3.0 15.7 1.5 5.3 3.7 0.0 4.7 14.5 2.8 1.9 2.7 2.3 19.3 98.0 8.8 3.0 6.7 0.5 1.1 11.9 31.4 5.6 46.0 46.3 5.7 2.9 0.5 61.1 0.0 1.2 4.9 0.0 52.9 99.7 2.3 15.2 97.5 5.4 2.8 51.0 0.0 7.2 11.1 9.1 2.4 7.9 1.2 2.7 3.5 1.5 1.7 4.0 0.2 0.0 2.3 8.7 4.9 5.5 0.4 4.0 2.9 9.6 14.7 5.1 2.8 EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 230.6" "Group enriched" "Detected in many" 7 "Alveolar cells type 1: 4163.5;Suprabasal keratinocytes: 1174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 268.1;RT4: 182.0;SK-BR-3: 256.2;T-47d: 156.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 42: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA014711: AB_1848147, HPA070816: " "unprognostic (1.75e-1)" "unprognostic (4.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (9.27e-2)" "unprognostic (8.90e-2)" "unprognostic (2.41e-2)" "unprognostic (4.40e-1)" "unprognostic (1.86e-1)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (2.85e-8)" "unprognostic (9.54e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (9.52e-2)" 56.8 9.7 15.5 12.4 15.5 0.7 49.5 14.8 17.1 51.0 18.6 48.0 15.5 25.9 45.5 152.1 35.5 17.7 64.1 13.6 15.6 20.3 83.2 230.6 5.7 16.1 16.8 54.9 13.7 32.8 13.3 23.0 16.0 38.8 34.1 2.0 39.2 17.3 22.5 140.6 28.3 22.3 15.2 16.0 39.1 7.2 18.8 5.3 27.7 25.4 32.8 39.6 72.9 15.7 28.7 39.1 15.9 18.9 35.0 30.0 31.3 40.0 36.8 23.9 35.7 128.5 98.2 0.2 12.6 48.4 17.2 123.9 41.1 49.8 31.3 0.1 26.1 0.1 76.6 72.1 6.1 0.2 0.4 18.4 13.1 31.9 3.2 5.4 10.1 0.1 9.6 2.6 66.9 268.1 0.4 0.6 18.3 46.4 9.5 7.5 18.2 61.7 5.5 182.0 22.0 25.0 49.6 256.2 15.2 45.2 156.6 6.2 5.7 75.5 32.2 25.6 22.7 0.8 1.0 0.2 33.2 0.5 75.7 1.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 1.1 0.3 0.3 0.3 0.2 0.1 15.5 15.5 14.8 17.1 13.6 15.6 16.1 16.8 16.0 15.2 18.8 15.7 239.7 4163.5 368.4 13.1 3.1 356.9 137.9 172.2 111.0 2.3 105.0 94.0 53.1 100.1 255.8 42.3 0.0 74.2 3.1 119.5 0.0 3.8 8.0 78.8 30.9 183.9 104.9 0.0 0.7 67.0 17.8 152.7 46.4 51.9 36.7 68.7 161.0 235.1 10.1 0.0 0.6 207.8 81.4 19.6 136.5 9.3 190.7 17.0 87.2 41.2 33.6 5.7 0.0 22.6 0.6 32.9 158.4 276.1 1.6 86.0 21.0 0.2 142.8 2.2 52.6 256.3 129.3 5.7 12.9 319.5 1174.3 48.0 9.3 73.3 178.5 221.4 EN1 ENSG00000163064 "Engrailed homeobox 1" Q05925 2 118842171-118847648 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.2;skeletal muscle: 13.9;skin 1: 10.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 5.6;Fibroblasts: 4.8;Melanocytes: 12.4;Skeletal myocytes: 12.0;Smooth muscle cells: 5.4" "Cancer enhanced" "Detected in many" "breast cancer: 5.6" "Region enriched" "Detected in many" 6 "midbrain: 18.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.1;ASC TERT1: 7.2;fHDF/TERT166: 13.3;HSkMC: 13.5;PC-3: 7.8;U-138 MG: 9.9;U-2197: 11.2" "Region enriched" "Detected in single" 5 "midbrain: 4.9" "Region enriched" "Detected in some" 6 "midbrain: 23.6" "CAB014884, HPA073141" Enhanced Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli rim" Nucleoplasm "CAB014884: , HPA073141: AB_2686573" "unprognostic (5.20e-2)" "unprognostic (1.61e-1)" "unprognostic (5.78e-2)" "unprognostic (4.84e-7)" "unprognostic (1.87e-3)" "unprognostic (1.90e-1)" "unprognostic (1.95e-3)" "unprognostic (1.16e-1)" "unprognostic (2.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.46e-1)" "unprognostic (3.38e-9)" "unprognostic (2.15e-2)" "unprognostic (1.88e-1)" "unprognostic (1.70e-1)" "unprognostic (9.30e-3)" 3.5 0.2 0.1 0.0 0.1 0.0 1.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.8 0.7 18.2 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 13.9 10.4 0.0 0.0 0.5 0.0 0.0 0.1 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.5 4.0 0.2 0.6 0.2 16.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 4.7 0.5 0.6 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.1 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.3 0.0 0.0 0.0 9.9 1.0 11.2 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.5 0.7 18.2 3.2 0.5 1.4 0.5 1.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 5.6 2.8 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 12.4 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 5.4 0.1 0.4 0.0 2.6 0.0 0.2 0.0 0.0 0.0 ENPP5 ENSG00000112796 "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5" Q9UJA9 6 46159185-46170980 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 243.6" "Cell type enhanced" "Detected in many" "Muller glia cells: 100.1;Respiratory ciliated cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.9" "Lineage enriched" "Detected in many" 5 "T-cells: 14.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 11.1;HSkMC: 7.1;SuSa: 6.2;T-47d: 8.7;U-266/84: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016902 Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 620000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" Cytosol Nucleoplasm "HPA016902: AB_1848172" "unprognostic (1.12e-1)" "unprognostic (5.19e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-1)" "unprognostic (7.61e-2)" "unprognostic (1.63e-1)" "unprognostic (5.01e-2)" "prognostic favorable (4.57e-4)" "unprognostic (1.96e-1)" "unprognostic (9.89e-2)" "prognostic favorable (4.04e-4)" "unprognostic (7.00e-2)" "prognostic favorable (4.44e-13)" "unprognostic (4.40e-2)" "unprognostic (2.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.60e-1)" 1.8 8.6 6.2 1.1 7.6 0.2 13.4 6.9 12.6 12.8 4.0 2.6 1.5 1.8 243.6 1.8 15.4 7.0 4.4 7.0 9.7 24.3 0.5 8.8 1.2 5.8 13.0 9.7 9.7 46.3 19.8 1.7 6.2 29.4 3.2 30.6 14.4 31.0 10.7 1.6 1.9 0.9 4.5 5.7 6.7 35.5 14.0 8.2 51.0 10.3 1.4 5.6 1.8 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.5 0.1 0.3 11.1 1.8 3.6 0.2 3.7 0.0 0.6 1.5 0.1 0.0 2.4 0.7 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.4 1.9 0.0 0.5 2.3 5.4 0.0 0.0 0.2 0.2 4.5 0.6 4.7 0.2 0.0 4.6 0.0 6.2 8.7 0.0 0.0 0.0 1.2 0.0 0.1 5.3 7.9 0.0 2.8 0.0 0.1 0.0 0.0 0.0 14.9 0.1 8.0 0.5 3.0 9.7 0.0 0.8 0.9 8.7 1.1 2.8 0.0 0.0 0.0 3.2 6.2 7.6 6.9 12.6 7.0 9.7 5.8 13.0 6.2 4.5 14.0 6.3 0.4 12.8 12.2 16.3 1.6 0.9 4.8 0.5 1.2 10.6 18.1 10.8 7.5 8.6 6.1 23.9 4.2 4.9 4.2 1.9 1.9 11.6 0.7 15.3 0.8 0.4 8.3 0.0 24.6 7.5 2.9 4.2 2.0 5.4 4.5 4.0 0.4 0.1 0.4 10.1 14.5 2.8 2.0 0.0 0.4 3.8 2.8 0.5 0.0 1.9 0.6 100.1 23.7 9.0 10.5 2.2 2.3 12.0 0.1 12.0 1.7 16.3 47.3 3.4 6.6 25.7 1.8 0.5 2.4 1.1 0.6 0.3 3.2 21.2 2.9 3.3 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 EPB41 "4.1R, EL1" ENSG00000159023 "Erythrocyte membrane protein band 4.1" P11171 1 28887091-29120046 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Actin-binding, Calmodulin-binding" "Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 80.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.6;Cone photoreceptor cells: 137.6;Erythroid cells: 187.1;Rod photoreceptor cells: 171.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 42.2" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 136.3;K-562: 136.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebellum: 105.6" "HPA028076, HPA028096, HPA028412, HPA028414" Supported Supported "Nuclear bodies,Plasma membrane,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No 1100000 "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cell Junctions" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA028076: AB_2672476, HPA028096: , HPA028412: AB_2672592, HPA028414: AB_10601366" "unprognostic (2.16e-1)" "unprognostic (1.96e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (4.58e-4)" "unprognostic (5.00e-2)" "prognostic favorable (5.87e-4)" "unprognostic (5.01e-3)" "unprognostic (5.40e-3)" "unprognostic (2.52e-2)" "unprognostic (6.65e-2)" "unprognostic (7.81e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 11.0 10.2 1.8 21.9 18.3 63.3 14.1 42.2 6.0 14.5 4.9 23.6 17.7 10.2 5.3 16.6 6.3 15.0 9.7 1.2 4.7 12.7 21.7 15.1 37.4 8.2 5.6 16.3 18.8 15.5 4.7 7.2 8.5 15.0 23.1 80.0 19.1 9.1 15.9 15.3 23.3 9.9 3.5 22.9 27.0 10.4 4.7 69.0 15.2 13.8 37.0 15.5 1.9 3.0 27.0 6.9 62.3 29.4 5.2 0.8 19.5 6.9 10.1 8.4 10.5 16.8 31.2 49.1 17.2 9.2 13.5 11.9 78.7 6.6 8.6 86.4 23.8 136.3 19.7 28.6 10.1 45.8 88.2 1.7 18.4 8.2 13.8 19.9 14.1 73.5 136.5 36.2 0.1 8.8 72.3 30.4 62.0 44.1 10.0 110.9 28.2 68.3 7.7 33.3 78.0 60.5 19.7 19.2 43.3 21.7 14.7 18.2 1.2 0.3 13.3 12.9 13.4 52.5 72.4 85.2 12.1 47.8 6.8 33.3 3.2 21.4 12.9 1.1 15.4 17.2 18.3 14.1 4.4 13.6 22.1 12.7 44.2 10.9 1.5 4.4 28.9 15.3 1.8 18.3 42.2 6.0 1.2 4.7 8.2 5.6 8.5 3.5 4.7 3.0 25.3 19.2 71.7 20.2 58.2 10.5 8.6 7.8 15.4 151.6 20.0 12.2 21.5 20.0 16.8 16.5 137.6 2.4 75.3 26.5 17.6 17.1 16.4 11.3 4.1 15.1 41.6 187.1 76.3 18.7 4.2 7.9 29.6 29.1 24.1 24.9 17.5 30.0 7.1 21.9 61.7 29.0 16.2 23.7 9.0 22.7 2.1 32.4 0.0 78.7 29.3 15.7 85.5 7.5 4.8 28.6 20.3 2.2 46.7 12.2 32.8 13.4 15.2 171.4 13.1 2.8 8.5 39.3 55.7 14.9 16.8 4.1 71.6 4.2 33.0 12.6 EPB41L4A NBL4 ENSG00000129595 "Erythrocyte membrane protein band 4.1 like 4A" Q9HCS5 5 112142441-112419313 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 64.3;Oligodendrocyte precursor cells: 164.4;Oligodendrocytes: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 30.1;HeLa: 36.5;RT4: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036580 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Nucleoplasm "HPA036580: AB_10669908" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (1.92e-3)" "unprognostic (3.64e-2)" "unprognostic (4.73e-2)" "unprognostic (5.59e-3)" "unprognostic (4.40e-2)" "unprognostic (8.38e-2)" "unprognostic (1.90e-1)" "unprognostic (3.97e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.65e-5)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (2.73e-1)" "unprognostic (1.92e-1)" 8.7 4.5 4.8 3.2 5.7 3.6 5.3 4.1 4.8 4.1 9.0 4.0 2.6 4.3 12.7 10.1 7.4 13.8 9.2 6.0 5.1 11.7 3.3 7.7 3.3 5.7 4.6 5.7 4.9 8.0 0.5 9.3 4.8 5.8 4.8 16.0 7.2 5.4 4.2 8.8 3.4 2.7 4.9 4.7 5.6 6.1 4.8 3.6 13.5 4.2 3.6 5.1 2.3 4.8 0.8 5.5 14.3 1.5 0.0 0.0 2.9 2.1 0.0 0.0 0.0 3.0 12.3 6.2 30.1 0.0 0.8 7.4 1.1 6.9 0.0 1.0 5.0 9.8 36.5 2.0 0.1 2.6 3.1 0.0 3.0 0.0 0.0 1.6 9.2 1.7 1.9 5.6 0.0 1.8 4.6 3.5 2.7 1.2 1.1 2.3 10.7 1.3 8.4 21.6 11.8 6.1 10.7 5.2 4.5 9.8 15.9 1.4 15.7 0.7 2.4 1.9 4.4 5.6 1.3 4.6 1.4 5.2 0.8 0.5 0.2 0.1 2.0 0.3 1.1 1.4 0.6 0.6 0.2 1.6 0.9 1.8 0.2 0.1 0.5 0.1 0.6 0.5 4.8 5.7 4.1 4.8 6.0 5.1 5.7 4.6 4.8 4.9 4.8 4.8 55.9 28.9 7.7 17.3 4.7 6.0 16.8 11.2 13.6 5.0 11.2 4.7 8.3 64.3 24.2 14.7 4.2 7.4 4.5 8.5 11.7 15.0 20.8 19.7 3.1 35.2 1.2 2.1 28.6 7.5 0.7 8.4 7.1 17.1 8.8 11.9 34.6 1.7 2.7 1.7 31.8 6.3 16.2 4.6 2.1 23.0 1.8 1.8 3.6 56.2 3.2 8.2 14.4 164.4 65.4 14.1 10.9 1.9 6.5 13.7 1.9 30.4 39.5 32.1 0.0 8.7 6.0 1.8 9.1 16.0 8.1 2.5 3.7 2.2 7.5 19.1 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.6;parathyroid gland: 69.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 138.6;Inhibitory neurons: 172.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 12.0;HEK 293: 35.1;RH-30: 31.7;THP-1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" NA NA 660000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 0.3 0.0 1.2 0.4 3.4 0.0 1.2 3.4 5.1 1.4 0.0 24.6 1.5 0.9 0.2 0.2 0.5 2.2 3.6 4.9 2.6 5.9 0.0 0.2 0.0 1.2 2.2 1.9 0.1 69.9 1.2 0.4 1.5 9.7 2.5 1.8 5.4 0.9 0.1 0.2 4.4 2.1 0.4 3.9 10.3 0.9 0.6 0.0 0.1 0.1 0.0 8.2 1.8 1.2 0.0 0.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 35.1 0.0 3.0 0.0 0.0 0.0 0.0 0.5 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.6 0.0 1.0 5.4 31.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.4 3.4 5.1 4.9 2.6 1.2 2.2 1.5 0.4 0.6 1.2 0.2 0.0 0.0 4.2 0.0 0.4 0.4 0.0 0.6 18.5 3.1 1.8 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 13.1 1.3 1.4 1.8 0.0 0.0 138.6 0.0 0.0 5.9 0.0 3.8 0.0 3.7 0.0 0.0 0.1 11.8 172.0 0.0 0.0 0.0 0.4 3.3 0.9 0.1 0.0 11.2 0.0 0.4 0.0 4.5 8.3 0.1 0.0 0.0 0.0 0.4 0.0 11.8 0.0 1.0 0.0 0.2 0.5 0.2 1.1 0.2 1.0 0.0 0.2 0.9 0.0 0.1 EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6" "Cell type enhanced" "Detected in many" "Astrocytes: 198.8;dendritic cells: 53.7;Early spermatids: 42.2;Excitatory neurons: 47.9;Inhibitory neurons: 44.3;Late spermatids: 41.2;Oligodendrocyte precursor cells: 77.9" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 33 "neutrophil: 24.0;plasmacytoid DC: 23.3" "Group enriched" "Detected in many" 33 "dendritic cells: 23.3;granulocytes: 24.0" "Group enriched" "Detected in some" 5 "HDLM-2: 63.9;HMC-1: 35.5;RPTEC TERT1: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: AB_2685895" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" 1.0 0.6 4.7 0.8 18.7 0.7 3.2 40.6 12.8 1.8 0.0 3.2 1.4 2.2 0.9 1.9 1.3 1.7 0.3 7.0 5.1 1.3 1.6 0.3 1.9 5.0 14.4 0.7 0.3 0.2 1.0 0.2 5.5 1.7 0.5 4.2 2.2 2.7 4.9 4.8 0.7 0.7 0.9 1.9 0.6 10.8 12.0 0.7 7.0 10.3 1.7 1.5 1.0 4.2 0.0 0.0 8.4 0.1 0.2 0.0 0.0 6.6 0.1 0.3 0.1 0.1 0.0 1.1 1.6 3.4 0.6 0.1 5.5 0.0 1.2 63.9 0.8 4.8 0.0 0.0 0.0 0.0 35.5 0.1 0.0 0.1 0.0 0.3 0.2 0.5 0.0 0.3 4.7 0.2 0.0 0.3 2.4 1.2 0.1 0.0 0.9 0.2 16.5 0.0 1.1 0.2 0.0 0.1 0.0 1.1 0.1 0.7 0.5 1.1 3.4 0.7 7.9 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 23.3 0.0 0.2 4.7 18.7 40.6 12.8 7.0 5.1 5.0 14.4 5.5 0.9 12.0 4.2 1.9 0.0 0.0 198.8 1.0 3.7 0.0 0.0 0.0 1.9 0.8 12.3 1.6 0.0 0.0 0.0 10.4 0.0 53.7 0.0 0.0 0.8 42.2 0.1 0.5 2.8 0.0 0.0 47.9 0.4 0.1 0.4 0.0 0.1 0.0 3.3 0.4 7.0 0.4 0.0 44.3 0.0 0.0 0.0 0.8 41.2 0.6 0.8 1.8 8.4 0.1 16.9 0.0 77.9 5.6 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.0 3.3 0.8 0.5 1.6 0.0 5.8 0.0 0.2 3.0 0.3 0.2 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPN2 "EHB21, KIAA1065" ENSG00000072134 "Epsin 2" O95208 17 19215615-19336715 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Oligodendrocyte precursor cells: 868.6;Oligodendrocytes: 258.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.9;eosinophil: 29.0;neutrophil: 9.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 29.0" "Cell line enhanced" "Detected in many" "SuSa: 127.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049809, HPA053360" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA049809: AB_2680893, HPA053360: AB_2682126" "unprognostic (1.38e-2)" "unprognostic (2.54e-2)" "unprognostic (2.58e-2)" "unprognostic (2.09e-1)" "unprognostic (1.94e-1)" "unprognostic (8.12e-3)" "unprognostic (6.73e-3)" "unprognostic (1.43e-1)" "unprognostic (8.89e-2)" "unprognostic (4.58e-3)" "unprognostic (3.42e-2)" "unprognostic (1.57e-1)" "prognostic favorable (9.13e-5)" "unprognostic (1.32e-1)" "unprognostic (9.40e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (8.15e-5)" 20.5 13.9 62.1 9.7 64.9 11.5 16.7 50.4 62.8 36.3 32.7 28.3 9.6 29.5 11.5 40.3 26.6 14.6 32.5 62.6 56.2 21.3 9.3 18.6 6.5 61.6 63.6 22.5 14.6 15.3 18.1 21.6 57.5 23.6 9.5 19.1 17.9 23.4 22.4 50.1 13.3 22.5 46.6 14.3 15.9 19.7 63.6 4.7 17.8 17.0 8.4 27.0 33.8 91.6 31.3 30.4 43.9 19.2 22.8 36.3 34.5 29.4 18.9 17.9 15.3 20.2 9.2 4.9 28.2 29.5 16.8 29.0 19.8 22.1 21.9 23.6 21.2 3.2 20.3 9.2 23.7 1.4 13.1 20.5 19.5 28.3 22.7 23.2 38.8 6.6 8.6 3.9 15.8 22.5 1.3 2.1 11.1 41.3 19.8 7.1 18.8 8.1 21.0 8.6 13.0 28.8 20.9 13.9 14.7 127.9 21.0 4.0 35.6 19.7 22.3 30.9 12.9 6.7 4.3 3.9 54.0 0.5 31.1 10.9 1.3 29.0 1.6 0.8 1.2 3.0 1.1 1.3 0.5 3.4 1.3 1.2 9.0 0.7 1.0 0.6 1.0 0.7 62.1 64.9 50.4 62.8 62.6 56.2 61.6 63.6 57.5 46.6 63.6 91.6 60.0 54.5 29.3 74.4 13.7 24.1 36.6 21.2 43.9 68.3 32.8 33.4 44.5 25.8 25.0 38.6 47.9 27.6 3.3 7.2 27.4 22.5 36.8 69.2 35.0 42.5 6.0 13.5 51.3 8.4 39.8 36.1 15.8 40.6 14.0 37.3 15.0 10.4 8.4 35.3 45.0 16.8 10.2 5.1 6.2 72.7 46.6 5.9 5.4 54.4 1.6 38.3 2.1 868.6 258.3 23.3 14.9 39.5 14.4 32.0 7.0 14.2 43.2 82.3 26.3 50.5 63.7 45.8 38.3 63.9 48.9 21.9 7.4 35.0 7.8 40.1 EPS8 ENSG00000151491 "Epidermal growth factor receptor pathway substrate 8" Q12929 12 15620134-15882329 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 317.0;Sertoli cells: 401.0;Smooth muscle cells: 313.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 22.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 253.0;HHSteC: 218.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003897 Approved Approved "Golgi apparatus" NA NA 17000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA003897: AB_1848224" "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-2)" "unprognostic (5.43e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "unprognostic (5.81e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (3.33e-7)" "unprognostic (2.68e-1)" "prognostic favorable (1.45e-7)" "unprognostic (7.47e-3)" "unprognostic (7.20e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.79e-2)" 62.3 13.0 12.9 16.1 17.4 0.6 33.7 15.3 14.0 53.9 14.1 49.7 37.6 46.2 47.1 20.5 20.1 56.0 26.4 11.1 17.2 55.8 37.8 29.0 9.4 18.5 20.1 49.2 15.1 21.6 3.5 53.1 19.7 16.4 53.7 39.8 13.4 39.8 13.8 11.9 42.7 53.7 15.5 11.9 32.0 15.6 16.1 4.8 22.8 24.3 5.2 51.7 21.4 20.8 65.0 38.8 37.7 1.4 253.0 177.6 53.1 73.6 59.8 34.5 46.1 33.3 97.3 0.0 2.4 140.4 114.4 16.4 11.3 9.5 52.4 0.2 12.6 5.7 11.2 34.7 218.1 4.4 0.2 159.8 42.8 91.7 115.7 44.6 17.7 0.2 0.1 0.2 169.0 17.5 0.2 2.8 5.2 50.3 30.8 0.0 109.5 0.8 97.7 92.5 3.1 4.9 21.4 12.4 91.5 6.2 34.2 4.3 28.7 54.7 14.3 32.4 30.7 3.6 0.4 0.1 32.1 10.7 160.0 0.0 2.7 0.2 0.2 10.8 0.1 1.3 0.9 0.4 5.5 0.3 1.1 0.5 4.4 1.0 22.2 0.4 0.1 1.7 12.9 17.4 15.3 14.0 11.1 17.2 18.5 20.1 19.7 15.5 16.1 20.8 121.4 12.8 175.9 91.1 11.6 17.0 39.6 32.0 13.6 9.7 28.7 42.8 27.6 87.2 58.3 23.9 66.7 33.0 15.2 317.0 60.7 69.4 67.6 87.4 72.0 61.4 38.3 0.4 2.2 68.9 7.3 73.4 81.1 152.2 6.3 139.4 36.0 36.0 65.8 6.7 31.1 54.5 67.1 54.1 35.6 49.4 134.8 46.2 35.6 148.0 8.6 15.4 0.0 121.2 96.9 97.0 217.8 43.6 5.2 26.9 69.0 114.6 104.8 153.7 401.0 18.1 313.1 10.9 4.2 22.8 13.1 21.1 11.8 40.0 80.0 97.6 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ERMP1 "FLJ23309, FXNA, KIAA1815" ENSG00000099219 "Endoplasmic reticulum metallopeptidase 1" Q7Z2K6 9 5765076-5833117 "Enzymes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 50.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 73.5;Granulosa cells: 53.4;Oligodendrocytes: 88.8;Urothelial cells: 66.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 76.8;RT4: 154.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055582 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA055582: " "unprognostic (1.93e-2)" "unprognostic (3.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.93e-2)" "unprognostic (2.97e-1)" "unprognostic (8.59e-2)" "unprognostic (4.30e-3)" "unprognostic (2.81e-1)" "unprognostic (5.46e-2)" "unprognostic (4.83e-3)" "unprognostic (3.14e-2)" "unprognostic (2.88e-2)" "prognostic favorable (5.83e-10)" "unprognostic (1.41e-1)" "unprognostic (4.00e-1)" "unprognostic (5.77e-2)" "unprognostic (1.36e-1)" 3.9 7.9 4.2 3.7 10.4 2.0 6.3 10.9 3.7 10.8 14.4 11.3 4.4 5.6 2.6 14.9 6.4 11.3 10.0 2.9 6.1 24.9 4.6 6.3 3.5 10.1 10.3 4.5 3.9 50.1 1.5 7.8 8.8 6.0 11.4 2.2 19.1 4.1 7.6 9.3 6.5 3.8 6.5 3.1 13.3 4.7 8.9 4.6 26.6 9.9 6.4 17.1 4.8 13.1 45.1 43.1 1.8 5.2 22.6 20.7 22.6 5.1 11.1 2.3 1.9 10.4 27.2 10.7 19.2 8.4 25.9 32.2 9.6 29.4 3.3 55.6 7.6 56.2 20.0 20.4 4.8 16.0 21.3 10.5 12.9 2.1 13.3 28.6 30.1 4.6 6.9 9.9 2.8 20.7 0.6 6.2 6.6 28.0 8.4 1.7 5.3 14.1 76.8 154.6 9.9 3.3 7.1 52.2 8.1 24.5 33.7 20.5 18.0 1.5 5.0 3.4 16.1 8.9 13.6 5.5 6.7 13.0 4.1 0.2 0.1 0.3 0.4 0.1 0.6 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.0 0.1 0.1 0.1 4.2 10.4 10.9 3.7 2.9 6.1 10.1 10.3 8.8 6.5 8.9 13.1 3.4 6.4 1.1 24.8 2.2 2.9 18.3 13.3 2.8 4.0 11.1 5.8 13.7 12.8 22.8 73.5 10.4 6.8 5.2 32.1 0.0 4.6 22.3 11.4 10.9 6.3 11.4 6.3 21.0 3.0 7.1 4.6 13.7 13.8 8.9 53.4 2.9 6.1 5.7 3.3 32.8 8.9 10.2 1.6 2.2 41.8 3.1 4.5 1.8 24.4 2.1 3.0 8.2 22.1 88.8 3.5 22.5 4.9 4.1 7.0 9.2 3.3 16.6 2.9 6.6 5.8 4.3 8.8 4.6 17.5 4.5 4.1 5.9 39.8 15.7 66.9 ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 405.9;Endothelial cells: 301.0;Hepatic stellate cells: 138.1;Sertoli cells: 151.2;Smooth muscle cells: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Group enriched" "Detected in many" 10 "HEL: 218.8;HUVEC TERT2: 277.9;TIME: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" 97.5 17.7 38.4 9.0 37.7 1.9 79.4 38.8 46.9 33.3 30.1 20.0 7.0 36.2 7.8 21.8 34.2 20.0 83.0 35.2 38.7 63.6 11.5 112.5 8.7 40.9 38.9 14.4 13.6 13.2 14.8 106.9 44.0 19.8 7.8 2.5 15.6 15.6 27.1 18.2 20.9 29.4 37.3 17.3 23.4 4.3 45.4 5.4 95.9 49.8 8.3 30.8 30.2 37.8 1.2 1.6 0.4 1.2 0.0 0.3 5.1 0.1 0.1 0.0 0.1 2.7 14.1 1.2 3.2 0.0 0.2 0.0 3.7 0.0 0.0 1.8 1.3 218.8 0.1 8.0 0.6 0.4 3.6 0.0 0.0 0.0 0.0 0.2 277.9 0.1 0.2 5.9 0.5 1.8 0.0 0.0 0.6 20.8 2.1 0.0 1.0 0.9 0.0 2.4 0.2 0.8 0.1 16.1 0.0 7.5 3.3 0.8 142.0 0.4 0.4 0.5 0.0 0.2 0.2 0.2 0.1 0.5 0.4 8.2 0.6 0.0 0.1 0.3 0.0 2.1 1.5 0.1 0.4 7.5 2.2 0.8 6.5 0.0 0.0 0.4 0.4 24.8 38.4 37.7 38.8 46.9 35.2 38.7 40.9 38.9 44.0 37.3 45.4 37.8 405.9 38.5 56.0 2.0 4.5 15.2 0.5 0.2 2.8 18.5 2.5 3.2 11.2 0.0 3.0 14.7 4.2 1.8 2.5 3.5 5.9 7.6 5.0 1.1 1.5 301.0 0.0 5.3 1.5 2.4 18.7 13.8 3.6 1.4 3.8 0.1 138.1 1.7 1.1 0.0 0.4 0.4 0.0 5.3 22.1 26.3 0.9 25.7 12.4 20.6 1.2 0.7 0.0 0.5 0.4 46.5 2.1 0.4 2.8 1.8 0.1 0.1 1.9 1.3 151.2 4.6 89.4 0.1 0.9 0.8 10.9 37.1 2.0 2.4 1.6 2.3 ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 263.1;dendritic cells: 378.9;Endothelial cells: 190.4;Hepatic stellate cells: 213.8;NK-cells: 399.6;T-cells: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 352.9;JURKAT: 362.3;U-698: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" 101.2 19.2 11.7 145.7 10.4 35.3 65.4 9.8 14.1 35.9 8.9 31.2 26.9 36.5 9.3 21.8 20.2 62.5 43.0 8.9 11.3 30.4 47.6 76.2 277.1 13.1 14.7 27.0 20.1 28.4 7.8 56.3 13.4 17.1 31.4 1.8 16.5 20.7 25.6 18.1 49.3 38.1 11.6 185.8 46.1 8.0 15.2 328.8 39.8 42.3 250.2 67.9 19.2 11.3 87.7 15.7 72.8 0.3 30.7 49.3 0.2 65.7 140.2 80.9 77.3 5.1 91.7 312.1 65.7 109.5 184.7 29.8 7.0 190.0 169.0 66.6 1.1 352.9 6.4 0.3 82.2 36.7 4.0 97.2 15.0 69.6 252.2 46.1 67.9 362.3 0.6 63.3 98.1 0.0 185.7 27.4 27.0 7.9 55.0 50.4 118.7 24.5 64.2 95.6 0.9 5.0 34.5 0.7 73.6 48.5 0.3 17.7 126.1 180.5 57.1 35.5 109.1 46.7 8.9 462.5 32.2 68.0 162.1 51.2 0.1 6.6 20.4 0.3 28.9 12.3 27.0 25.0 0.2 9.2 32.5 26.1 1.1 27.8 1.0 6.2 33.3 9.5 11.7 10.4 9.8 14.1 8.9 11.3 13.1 14.7 13.4 11.6 15.2 11.3 263.1 25.6 26.5 2.9 125.6 114.8 41.0 12.4 1.8 0.0 8.2 7.2 9.0 4.3 24.3 11.0 0.0 0.2 378.9 13.1 0.0 31.9 6.2 26.3 51.0 190.4 15.5 13.7 2.0 22.6 0.5 45.5 17.3 66.2 19.6 1.3 213.8 5.4 7.3 0.0 25.6 15.0 10.2 18.3 48.2 1.5 14.0 12.5 69.4 65.6 16.8 0.2 399.6 55.3 9.5 99.3 6.6 15.4 129.6 26.8 2.2 4.6 5.9 0.2 105.2 55.5 76.6 0.7 1.8 1.5 63.2 0.4 323.2 40.4 5.8 32.6 EXOC2 "FLJ11026, SEC5L1, Sec5p" ENSG00000112685 "Exocyst complex component 2" Q96KP1 6 485154-693139 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.8;Inhibitory neurons: 80.1;Microglial cells: 68.4;Oligodendrocytes: 73.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032093 Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA032093: AB_10611964" "unprognostic (1.61e-1)" "unprognostic (4.69e-1)" "unprognostic (1.52e-1)" "unprognostic (9.32e-2)" "unprognostic (1.91e-2)" "unprognostic (2.48e-1)" "unprognostic (1.82e-3)" "unprognostic (1.34e-1)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (5.32e-2)" "unprognostic (2.02e-1)" "unprognostic (8.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (2.20e-1)" 10.2 8.3 11.0 11.5 11.7 6.6 10.9 11.4 11.2 10.1 11.6 9.1 8.6 8.7 5.2 12.2 6.5 8.9 11.6 11.2 11.5 9.3 10.3 11.3 13.4 11.6 11.6 7.8 6.6 11.6 8.2 18.0 12.5 7.9 10.0 13.4 8.0 7.9 10.1 11.8 9.3 9.2 11.0 13.1 8.9 16.1 11.3 18.6 14.2 10.4 14.1 10.8 9.1 14.4 21.0 15.2 26.0 28.5 23.2 20.8 15.7 18.5 21.5 21.7 25.8 20.4 11.0 15.5 44.0 22.3 32.7 17.7 29.2 32.2 25.7 48.4 30.9 19.8 18.5 20.4 29.1 21.2 18.8 18.1 25.9 15.5 18.0 21.4 36.9 30.0 39.4 11.1 27.3 18.1 28.6 20.6 26.4 18.6 15.1 26.6 22.5 31.3 19.5 22.4 25.4 14.9 14.8 9.0 29.1 48.4 23.2 12.9 54.1 19.6 14.1 24.6 17.4 27.2 56.8 16.4 19.8 17.4 61.0 11.6 9.0 10.2 17.1 11.0 20.9 13.5 17.2 18.3 14.1 14.5 16.2 15.7 2.8 14.8 17.7 11.1 21.1 14.4 11.0 11.7 11.4 11.2 11.2 11.5 11.6 11.6 12.5 11.0 11.3 14.4 12.6 3.2 14.5 35.6 15.9 4.8 3.8 6.2 6.2 9.0 10.1 9.3 8.6 2.8 6.5 5.5 8.4 16.0 18.5 6.1 7.9 6.2 11.0 7.3 7.0 11.1 2.4 8.2 75.8 5.1 7.1 7.6 6.1 8.2 5.1 11.8 8.6 8.2 10.0 8.4 80.1 6.8 12.2 9.0 5.8 3.8 6.8 8.7 5.4 68.4 10.8 4.6 13.4 49.3 73.4 6.9 5.1 9.1 11.3 6.4 4.1 8.2 9.0 9.3 0.0 7.3 8.9 21.8 17.5 9.9 7.7 12.9 18.3 7.4 5.9 6.0 EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111826 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 229.6;Inhibitory neurons: 421.4;Microglial cells: 144.3;Oligodendrocyte precursor cells: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 95.5;fHDF/TERT166: 82.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain NA Yes 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.85e-1)" 5.1 4.2 2.0 5.2 2.5 1.1 4.3 2.3 2.3 7.6 3.9 7.7 14.1 4.9 2.9 5.5 3.8 5.8 7.0 3.4 1.3 3.8 13.3 7.9 3.0 1.1 2.1 5.0 5.5 3.3 1.8 11.1 1.0 5.0 8.2 2.7 3.2 7.7 1.5 7.8 11.7 6.1 1.4 5.1 5.3 2.4 1.2 3.0 5.2 2.4 3.8 11.8 4.2 1.9 29.3 8.5 13.5 5.5 22.8 23.0 5.9 51.5 95.5 40.9 39.4 10.0 3.1 0.5 24.8 82.1 24.0 19.8 5.0 31.4 55.7 12.5 9.9 1.5 5.9 6.5 10.0 0.0 1.6 10.8 10.8 38.8 38.5 47.7 28.1 2.9 0.9 7.4 18.7 3.2 1.8 0.2 4.6 13.7 10.1 0.0 4.1 1.3 23.1 7.6 4.5 4.0 8.0 3.9 9.2 32.6 5.3 0.5 32.0 35.2 28.7 32.0 15.8 5.5 5.1 2.4 36.5 0.0 9.2 0.1 0.4 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.3 0.1 2.0 2.5 2.3 2.3 3.4 1.3 1.1 2.1 1.0 1.4 1.2 1.9 21.1 19.2 6.0 127.3 3.0 54.8 23.0 27.7 10.2 23.6 7.8 10.8 6.5 24.3 13.7 7.3 14.6 6.5 5.1 49.2 0.0 37.3 1.8 17.7 37.1 25.9 4.8 1.7 229.6 20.1 3.9 32.6 11.7 18.2 7.0 108.3 16.8 32.9 2.5 10.1 421.4 25.5 4.1 37.9 13.9 2.7 17.4 9.6 19.6 144.3 8.1 5.9 4.1 162.8 101.8 27.4 16.1 36.1 5.3 19.3 44.9 4.9 14.2 22.4 0.0 17.1 36.4 0.6 5.1 12.6 47.3 12.2 4.2 35.0 26.3 26.8 EYA2 EAB1 ENSG00000064655 "EYA transcriptional coactivator and phosphatase 2" O00167 20 46894624-47188844 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 55.6" "Cell type enhanced" "Detected in many" "Astrocytes: 153.8;Basal prostatic cells: 47.5;Basal respiratory cells: 50.4;Endometrial ciliated cells: 43.7;Glandular and luminal cells: 53.8;Oligodendrocyte precursor cells: 48.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 69.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 40.1;SCLC-21H: 58.3;U-266/70: 110.9;U-266/84: 139.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027024, HPA059291" Uncertain Supported Cytosol NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA027024: AB_1848334, HPA059291: AB_2683967" "unprognostic (1.08e-1)" "unprognostic (5.71e-3)" "unprognostic (4.03e-1)" "prognostic favorable (4.30e-5)" "unprognostic (3.32e-2)" "unprognostic (1.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.65e-1)" "unprognostic (7.06e-2)" "unprognostic (2.15e-1)" "unprognostic (2.78e-1)" "unprognostic (4.17e-3)" "unprognostic (1.56e-1)" 12.0 1.5 12.3 2.4 14.1 0.0 11.0 15.6 12.3 55.6 11.2 9.3 0.3 17.2 3.7 34.2 34.0 1.8 5.0 10.7 11.8 4.7 2.1 2.2 0.8 14.6 14.4 0.7 1.9 9.4 5.3 6.3 13.7 23.6 3.1 1.2 31.2 9.3 2.5 5.3 1.1 1.8 11.8 0.6 8.9 5.6 13.4 18.8 14.6 3.4 6.6 4.9 16.5 11.0 0.2 4.4 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 2.5 1.9 0.3 40.1 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.1 0.3 2.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 7.7 0.1 0.0 0.6 0.1 0.0 0.1 0.8 0.5 0.0 0.0 58.3 0.0 0.0 24.8 0.0 3.0 5.3 0.2 0.0 0.0 4.5 0.3 8.8 110.9 139.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 14.1 15.6 12.3 10.7 11.8 14.6 14.4 13.7 11.8 13.4 11.0 0.4 0.0 0.0 153.8 0.9 0.6 47.5 50.4 14.8 0.4 7.8 7.6 0.5 2.8 33.0 0.0 6.2 27.7 0.0 2.5 0.0 0.9 0.2 43.7 3.9 0.6 1.2 0.0 1.5 0.0 3.0 4.8 9.2 53.8 1.3 9.8 0.4 3.3 7.4 0.0 5.1 0.6 34.6 0.0 0.4 0.3 0.0 1.1 3.6 13.1 2.6 0.0 0.0 48.7 1.0 1.1 1.7 0.7 3.4 10.9 0.0 6.3 22.2 0.4 0.0 0.3 2.8 0.2 7.4 16.0 0.3 10.8 0.6 4.2 3.6 34.6 EZR VIL2 ENSG00000092820 Ezrin P15311 6 158765741-158819368 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004035, HPA021616, CAB047324, CAB075739" Enhanced Enhanced "Plasma membrane" NA NA 42000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB004035: AB_2100309, CAB047324: , CAB075739: AB_2665745, HPA021616: AB_1848342" "unprognostic (4.79e-3)" "unprognostic (1.48e-1)" "unprognostic (1.97e-2)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (5.59e-2)" "prognostic favorable (9.56e-8)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-2)" "unprognostic (9.00e-2)" 88.2 186.6 100.7 98.4 99.5 135.2 59.8 86.0 96.8 77.1 224.4 133.5 158.8 35.6 78.4 260.3 114.6 116.1 116.3 96.2 95.6 159.1 57.9 173.2 185.6 97.6 105.3 44.7 112.6 447.4 42.8 233.0 91.7 81.4 103.6 10.7 89.9 72.2 46.9 187.8 257.1 36.6 99.3 75.6 273.7 55.9 98.9 108.8 126.1 25.5 216.3 219.0 98.6 91.1 668.3 355.4 86.5 125.0 9.3 10.3 502.7 204.7 67.1 225.7 189.2 420.9 357.7 667.1 197.2 235.2 108.5 497.7 172.2 228.0 259.5 235.3 111.2 14.0 204.9 187.5 223.2 167.7 98.9 16.6 172.9 212.9 205.1 191.4 150.2 90.8 134.9 316.7 132.3 175.9 239.3 199.6 144.5 180.6 117.6 176.9 40.7 152.5 462.1 198.6 156.3 127.2 358.5 507.7 37.9 391.5 124.1 218.5 195.3 72.6 233.4 101.1 319.9 216.5 212.8 566.9 45.4 84.9 88.5 177.2 83.4 103.7 195.9 190.8 233.2 466.5 205.6 245.1 181.9 389.7 108.6 146.3 36.2 133.6 202.9 84.5 385.7 298.2 100.7 99.5 86.0 96.8 96.2 95.6 97.6 105.3 91.7 99.3 98.9 91.1 47.4 951.9 547.8 111.3 799.6 614.7 809.5 202.4 247.0 11.2 240.4 144.4 311.0 154.4 726.2 156.3 0.0 406.1 372.4 806.8 97.8 302.3 10.2 782.9 75.4 71.0 159.9 46.5 0.4 256.1 560.3 213.1 500.5 844.5 119.0 40.8 25.4 37.5 113.3 0.0 0.5 415.3 179.0 79.1 820.5 32.8 135.5 297.5 321.9 12.2 110.5 35.7 62.8 2.0 0.7 618.3 631.2 294.2 564.9 416.7 694.2 238.1 1248.4 5.1 249.8 205.5 136.3 52.5 61.7 430.4 726.5 1243.4 483.8 102.3 312.9 1142.8 FABP9 "PERF, PERF15, T-FABP" ENSG00000205186 "Fatty acid binding protein 9" Q0Z7S8 8 81458253-81461579 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "skin 1: 40.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073619 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA073619: AB_2732229" "unprognostic (2.99e-1)" 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 40.9 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.4 0.0 0.2 0.2 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAF1 "CGI-03, hFAF1, HFAF1s, UBXD12, UBXN3A" ENSG00000185104 "Fas associated factor 1" Q9UNN5 1 50437028-50960267 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 202.4;Excitatory neurons: 296.7;Inhibitory neurons: 278.9;Microglial cells: 177.1;Oligodendrocyte precursor cells: 269.9;Oligodendrocytes: 424.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018253, CAB072814" Approved Supported Nucleoplasm NA NA 12000 "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB072814: , HPA018253: AB_1848351" "unprognostic (1.52e-1)" "unprognostic (1.25e-2)" "unprognostic (6.49e-3)" "unprognostic (4.69e-2)" "unprognostic (6.35e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (1.82e-1)" "unprognostic (9.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.01e-3)" "unprognostic (6.42e-3)" 18.2 16.8 21.0 9.2 22.0 21.0 18.5 21.8 27.5 18.9 18.7 23.7 12.4 18.2 11.7 23.1 15.7 8.7 34.9 22.3 22.1 21.5 23.6 14.9 13.1 21.5 21.5 19.9 26.2 23.2 20.6 10.6 22.0 18.5 12.7 19.6 18.1 16.3 67.9 28.1 16.4 13.4 21.8 14.0 18.2 47.8 21.2 22.2 18.3 37.6 14.1 21.4 18.7 25.9 37.4 27.1 23.1 39.3 22.4 21.1 33.9 35.5 32.1 53.9 48.8 30.4 26.0 59.9 25.7 30.5 47.5 27.2 37.3 33.1 45.9 40.1 33.5 49.9 33.5 31.6 36.4 54.3 28.5 19.8 29.4 57.0 69.4 27.8 29.5 44.5 58.9 0.2 28.1 15.0 56.6 43.0 30.6 49.3 19.2 52.1 50.7 0.0 54.9 33.1 0.3 28.6 32.3 64.9 56.4 32.0 20.4 64.1 18.2 30.4 37.3 37.8 0.2 45.1 50.6 69.3 0.0 77.6 35.7 1.1 2.1 4.9 4.0 2.7 5.5 2.5 3.6 4.0 3.6 4.2 4.3 2.8 0.7 4.3 3.5 2.9 6.1 1.6 21.0 22.0 21.8 27.5 22.3 22.1 21.5 21.5 22.0 21.8 21.2 25.9 17.9 6.4 18.2 202.4 26.9 21.4 38.5 27.8 33.6 19.9 16.9 16.9 43.9 11.5 27.2 16.5 27.1 14.2 18.0 13.1 29.4 8.8 75.1 15.1 15.6 14.2 11.4 44.6 296.7 11.6 28.2 16.0 29.0 16.9 5.7 19.2 10.4 18.2 11.4 16.8 278.9 17.8 6.1 13.6 18.0 117.2 11.1 15.4 16.0 177.1 8.9 20.0 15.5 269.9 424.4 8.5 9.7 10.9 35.4 18.3 20.0 28.3 32.7 33.0 6.6 26.2 20.3 36.9 15.6 37.9 28.1 15.3 27.9 19.6 21.6 34.1 FAM104A FLJ14775 ENSG00000133193 "Family with sequence similarity 104 member A" Q969W3 17 73207353-73236753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 44.8;testis: 153.0" "Group enriched" "Detected in all" 4 "Early spermatids: 1305.1;Late spermatids: 1771.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021459, HPA079514" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "HPA021459: AB_1848361, HPA079514: " "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (5.02e-3)" "unprognostic (3.23e-2)" "unprognostic (2.28e-2)" "unprognostic (3.05e-2)" "prognostic unfavorable (2.12e-7)" "unprognostic (5.19e-2)" "unprognostic (2.31e-2)" "unprognostic (4.88e-2)" "unprognostic (4.20e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (1.26e-10)" "unprognostic (6.70e-2)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" 16.6 11.7 13.1 14.1 13.0 44.8 15.3 16.9 14.0 14.4 11.1 14.7 12.6 11.7 12.5 17.8 11.1 10.4 12.4 12.9 11.3 10.8 13.9 12.8 17.8 12.0 11.5 12.2 15.0 12.2 16.0 17.8 11.5 14.1 12.4 14.0 12.3 11.1 17.1 21.6 12.8 11.2 11.4 17.0 21.7 153.0 12.6 20.9 11.8 12.0 16.9 13.4 14.8 13.7 41.8 33.5 16.7 31.0 24.7 23.1 54.1 33.4 34.7 35.9 36.9 28.3 26.3 24.3 26.7 32.2 35.0 26.0 21.4 24.3 38.7 28.6 28.7 35.4 29.1 43.5 32.9 31.1 58.1 24.6 31.6 31.9 23.2 23.7 42.6 28.8 28.0 39.6 43.6 28.5 55.7 21.5 22.9 30.7 42.5 30.1 46.3 23.5 27.6 33.7 27.3 36.1 19.6 28.2 36.7 31.0 39.4 31.8 29.8 42.3 49.1 29.1 39.4 38.5 41.5 29.8 37.9 33.7 31.9 72.4 49.4 87.7 57.1 44.6 55.5 53.5 69.6 65.7 48.8 55.8 50.1 60.9 81.9 68.9 49.8 31.7 128.5 82.5 13.1 13.0 16.9 14.0 12.9 11.3 12.0 11.5 11.5 11.4 12.6 13.7 37.1 9.6 10.2 7.5 24.2 57.0 20.7 42.3 17.6 17.7 22.5 21.1 5.6 22.8 26.9 22.0 6.2 122.3 23.0 20.8 31.3 32.7 1305.1 21.9 16.0 23.9 19.8 103.6 14.2 25.3 70.1 19.4 28.5 24.6 29.2 20.4 18.2 18.5 35.6 26.9 14.1 22.9 26.4 21.8 34.2 1771.9 35.1 25.5 24.9 10.3 32.2 20.2 33.0 10.6 11.3 32.1 20.1 24.0 30.4 32.8 26.4 18.9 27.4 19.7 6.6 14.8 43.7 277.3 60.7 29.9 65.8 324.9 32.7 21.3 20.7 51.8 FAM107A "DRR1, TU3A" ENSG00000168309 "Family with sequence similarity 107 member A" O95990 3 58564117-58627610 "Predicted intracellular proteins" "Cell cycle, Growth regulation, Stress response" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 1923.8;choroid plexus: 1389.1" "Cell type enhanced" "Detected in many" "Adipocytes: 196.3;Astrocytes: 81.9;Endothelial cells: 121.3;Hepatic stellate cells: 150.6;Muller glia cells: 125.0" "Cancer enriched" "Detected in many" 6 "glioma: 110.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 20.7;HUVEC TERT2: 64.9" "Low region specificity" "Detected in all" HPA055888 Enhanced Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA055888: AB_2682957" "unprognostic (1.20e-2)" "unprognostic (1.19e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.11e-1)" "unprognostic (7.80e-3)" "prognostic favorable (3.38e-4)" "unprognostic (1.92e-1)" "unprognostic (1.64e-1)" "unprognostic (5.73e-2)" "unprognostic (7.82e-3)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (1.33e-2)" "unprognostic (2.82e-1)" "unprognostic (1.92e-1)" "unprognostic (7.95e-3)" 73.2 7.5 1824.7 8.3 1801.2 0.3 58.6 1490.8 1923.8 34.5 1389.1 36.9 5.4 36.3 53.3 29.2 87.0 16.0 140.4 1745.7 1736.7 45.0 5.5 93.2 3.1 1611.9 1644.5 11.8 23.3 5.9 109.6 29.4 1613.0 80.5 16.0 85.1 40.6 38.0 26.3 23.3 45.2 42.5 1564.5 25.7 37.7 5.7 1698.7 43.9 51.4 32.8 8.6 68.9 41.6 1770.4 0.0 0.0 0.9 0.0 20.7 1.3 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.1 5.8 0.0 0.2 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1.4 0.0 0.1 0.1 0.3 64.9 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.0 3.6 0.3 0.2 0.2 0.1 0.1 0.0 0.1 1.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1824.7 1801.2 1490.8 1923.8 1745.7 1736.7 1611.9 1644.5 1613.0 1564.5 1698.7 1770.4 196.3 6.4 5.5 81.9 0.5 2.2 50.8 0.3 2.2 5.2 2.3 1.3 26.5 4.3 3.2 38.6 52.1 0.1 0.4 0.0 9.8 1.1 14.5 23.2 2.4 121.3 3.6 2.7 1.4 0.2 0.0 18.4 0.0 39.3 1.3 5.9 150.6 1.6 0.0 3.3 5.3 0.0 0.0 2.2 3.7 32.4 32.9 1.9 5.4 14.0 0.0 125.0 0.0 2.0 0.6 0.3 0.0 11.7 1.3 7.3 0.2 4.5 2.3 50.2 6.6 6.6 10.4 0.7 0.4 0.4 2.7 0.0 1.0 0.5 0.0 2.2 FAM126A "DRCTNNB1A, HCC, HYCC1, hyccin" ENSG00000122591 "Family with sequence similarity 126 member A" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 133.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042873: AB_2678207" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-4)" "unprognostic (1.35e-1)" "unprognostic (9.76e-3)" "unprognostic (1.30e-2)" "unprognostic (7.23e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (6.04e-7)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (9.03e-4)" 14.9 4.7 5.0 8.5 6.9 4.2 12.2 4.4 6.5 9.7 7.9 9.7 9.4 8.7 1.4 12.2 6.7 11.4 10.5 12.1 4.5 4.7 8.5 13.7 11.5 5.0 5.9 6.6 6.2 2.3 5.0 14.8 5.4 5.9 4.4 4.9 6.8 4.8 25.0 4.9 6.9 11.5 4.5 11.8 4.6 12.0 6.3 4.2 6.6 15.3 9.2 9.4 11.2 7.8 22.4 12.4 63.6 22.3 61.3 100.9 10.6 103.0 101.8 41.6 63.9 19.8 10.6 13.3 15.9 82.6 87.2 7.7 44.3 14.7 72.6 6.6 22.4 14.7 18.1 13.0 48.0 19.3 15.7 41.1 9.2 85.0 61.3 83.4 42.5 7.5 30.4 58.6 77.5 7.9 10.8 24.2 63.0 0.1 22.9 15.7 63.5 9.5 13.1 11.2 10.4 0.1 38.1 0.4 19.2 52.5 8.2 20.4 51.0 150.0 18.3 71.8 37.4 67.2 30.6 60.9 91.1 12.5 112.6 4.7 2.9 13.7 1.4 7.8 1.3 6.4 2.6 1.3 3.9 7.4 0.9 1.5 0.3 2.1 9.8 1.6 4.0 2.5 5.0 6.9 4.4 6.5 12.1 4.5 5.0 5.9 5.4 4.5 6.3 7.8 27.8 3.2 15.1 19.6 29.1 25.5 5.1 8.3 15.9 60.3 5.4 32.4 21.9 2.8 4.2 3.7 2.1 11.8 28.8 0.5 0.0 6.8 49.0 12.5 22.4 31.4 7.7 19.8 13.6 4.8 15.5 42.9 2.6 11.3 8.2 8.6 26.0 17.7 15.2 16.8 13.6 3.0 2.0 25.1 55.2 22.4 20.2 31.5 35.6 47.8 24.0 6.8 11.3 23.6 133.2 3.6 1.4 19.5 26.4 4.7 8.3 5.7 2.4 4.6 19.7 24.0 31.7 72.2 11.1 35.0 24.0 6.0 20.6 12.2 4.7 6.5 FAM162A "C3orf28, E2IG5" ENSG00000114023 "Family with sequence similarity 162 member A" Q96A26 3 122384176-122412334 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 625.3;Distal tubular cells: 540.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035856, HPA075611" Approved Supported Mitochondria NA NA 19000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA035856: AB_10611965, HPA075611: " "unprognostic (1.17e-2)" "unprognostic (1.42e-1)" "unprognostic (5.64e-2)" "unprognostic (1.10e-1)" "unprognostic (3.99e-1)" "unprognostic (7.84e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (5.91e-3)" "unprognostic (8.74e-2)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.06e-1)" "unprognostic (4.10e-2)" "prognostic favorable (3.93e-4)" 49.0 105.7 54.8 31.3 60.2 39.9 43.9 57.3 82.2 84.5 57.1 145.9 56.1 49.5 59.4 207.6 49.7 46.2 174.2 57.1 58.5 107.6 200.3 32.0 32.9 55.9 57.2 84.3 133.9 116.6 51.0 17.6 55.6 74.6 149.0 83.5 59.8 49.2 141.0 89.8 56.3 44.6 56.6 31.7 93.2 43.6 58.8 34.7 44.1 142.6 42.7 76.9 131.5 55.6 132.0 27.7 40.4 75.6 72.1 66.4 20.7 52.9 46.8 49.0 123.9 69.4 58.7 142.1 89.2 18.2 40.3 89.8 73.5 128.1 130.0 74.0 55.1 115.6 44.0 125.8 47.4 114.0 39.6 77.3 65.5 46.7 97.9 164.3 66.0 137.7 79.2 55.6 71.1 52.0 116.9 137.9 59.5 294.9 144.4 69.5 57.8 186.9 144.3 314.9 60.1 48.1 39.4 92.4 114.3 59.9 57.9 55.7 47.0 48.4 34.6 28.7 55.6 108.8 39.9 144.8 143.3 109.7 22.8 9.9 25.8 75.7 58.3 68.2 86.9 75.3 79.5 74.0 84.6 68.1 85.1 88.6 8.5 50.6 75.9 70.4 80.4 38.8 54.8 60.2 57.3 82.2 57.1 58.5 55.9 57.2 55.6 56.6 58.8 55.6 55.7 28.9 46.0 41.1 68.2 128.1 155.3 625.3 82.0 31.5 80.6 109.5 338.4 84.4 188.6 130.6 47.9 51.4 47.9 477.5 540.0 148.2 102.5 82.0 30.1 49.8 106.9 47.7 33.0 177.6 47.8 78.7 84.6 79.2 85.7 59.3 44.6 280.4 92.7 38.7 30.4 374.3 240.1 66.7 108.9 33.1 134.5 61.2 104.9 7.5 108.9 79.7 45.3 22.1 21.6 141.6 313.2 148.6 61.2 121.4 186.2 466.2 95.5 29.9 105.2 83.2 315.3 146.4 68.3 315.1 132.8 47.2 66.0 121.1 358.4 210.9 FAM162B "bA86F4.2, C6orf189" ENSG00000183807 "Family with sequence similarity 162 member B" Q5T6X4 6 116752197-116765719 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 65.2" "Group enriched" "Detected in some" 4 "Adipocytes: 34.6;Sertoli cells: 65.7;Smooth muscle cells: 105.1" "Cancer enriched" "Detected in many" 18 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 8.7;BJ hTERT+: 23.5;BJ hTERT+ SV40 Large T+ RasG12V: 22.1;HHSteC: 6.3;HSkMC: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036112, HPA060342" Enhanced NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA036112: AB_10696649, HPA060342: AB_2684258" "unprognostic (1.81e-1)" "unprognostic (5.65e-3)" "unprognostic (1.54e-1)" "unprognostic (3.38e-1)" "unprognostic (5.45e-2)" "unprognostic (1.86e-5)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-2)" "unprognostic (2.44e-2)" "unprognostic (7.32e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.22e-2)" "unprognostic (1.72e-1)" "unprognostic (2.73e-3)" "unprognostic (4.34e-2)" 14.7 14.9 3.3 0.8 4.4 0.0 10.9 1.9 7.0 13.2 2.5 3.3 0.9 5.8 7.5 4.4 10.1 5.2 9.1 4.6 2.7 4.5 0.9 17.9 1.5 3.0 2.5 5.7 1.7 3.7 6.6 65.2 2.7 6.2 2.1 0.2 8.2 13.4 5.4 3.0 2.3 3.7 2.7 0.1 3.5 2.5 2.8 1.8 9.7 10.6 1.2 7.9 9.9 4.7 0.0 0.0 0.0 0.0 2.3 0.1 0.0 8.7 23.5 3.7 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.4 1.9 7.0 4.6 2.7 3.0 2.5 2.7 2.7 2.8 4.7 34.6 0.0 0.0 1.3 0.0 1.3 0.1 0.0 1.2 0.0 0.9 0.8 0.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 16.9 0.7 15.7 13.7 0.0 0.0 14.8 0.0 0.2 14.1 0.0 0.4 0.0 0.1 3.6 0.0 0.5 0.0 6.9 0.0 0.0 0.0 2.1 2.2 2.1 0.7 1.8 3.7 0.0 0.0 0.0 6.6 0.5 0.2 0.0 5.3 0.0 0.2 0.0 0.1 0.0 0.1 65.7 2.2 105.1 10.3 5.9 0.6 0.9 0.5 2.3 0.1 0.0 0.0 FAM210B "C20orf108, dJ1167H4.1, DKFZP434A1114" ENSG00000124098 "Family with sequence similarity 210 member B" Q96KR6 20 56358974-56368663 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 449.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 299.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042652 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA042652: AB_2678098" "unprognostic (3.29e-1)" "prognostic favorable (5.44e-4)" "unprognostic (3.24e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-1)" "unprognostic (3.34e-2)" "unprognostic (9.45e-2)" "prognostic favorable (4.26e-4)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" "prognostic favorable (1.44e-10)" "unprognostic (1.08e-1)" "unprognostic (3.27e-2)" "unprognostic (1.84e-1)" "unprognostic (3.00e-1)" 38.2 87.6 32.1 13.9 34.1 85.2 62.0 30.0 33.6 43.7 37.7 39.8 24.7 36.5 45.7 31.1 40.1 40.6 43.9 33.9 32.6 34.6 100.3 28.2 13.9 29.6 33.8 108.9 41.5 32.7 28.1 36.7 29.9 66.8 30.6 30.0 54.9 58.7 75.2 36.5 23.3 34.2 29.6 19.6 34.2 14.1 35.9 20.6 28.4 102.2 20.0 32.5 32.7 29.1 19.9 7.5 29.3 71.6 83.2 93.4 57.1 23.8 53.4 42.6 48.7 13.9 9.6 1.6 12.1 40.9 24.6 56.2 15.9 68.7 71.0 2.9 24.9 12.2 16.9 132.0 54.4 1.3 7.4 80.2 75.2 24.1 34.0 49.3 69.4 10.2 93.6 12.7 52.7 20.6 10.4 5.4 24.9 29.0 46.7 0.1 60.4 15.9 21.9 22.9 40.4 72.9 57.9 124.6 299.1 62.3 55.0 11.1 48.4 37.8 25.2 61.0 14.7 9.9 10.9 0.4 30.0 7.7 25.2 2.3 2.3 6.9 1.7 3.3 1.3 1.1 1.9 2.3 1.7 1.3 2.0 1.9 1.0 1.4 1.5 1.5 2.3 1.0 32.1 34.1 30.0 33.6 33.9 32.6 29.6 33.8 29.9 29.6 35.9 29.1 30.3 16.0 29.3 4.2 7.4 24.9 85.4 28.2 70.6 10.3 57.5 98.8 56.8 54.3 19.3 16.5 39.6 77.7 13.5 23.8 64.6 27.9 1.0 41.4 49.0 28.8 50.9 449.3 5.7 19.5 26.3 46.1 44.9 37.4 19.1 47.5 46.1 154.5 28.0 1.7 6.6 28.6 20.3 44.1 21.2 4.7 66.8 26.2 37.4 5.6 36.6 27.8 14.4 4.0 8.4 35.7 15.3 155.7 9.4 48.7 34.1 46.1 15.6 19.2 19.7 28.1 37.1 1.1 9.4 68.6 32.5 41.9 14.6 123.4 33.4 56.3 FAM220A "ACPIN1, C7orf70, MGC12966, SIPAR" ENSG00000178397 "Family with sequence similarity 220 member A" Q7Z4H9 7 6329411-6348981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 89.7;testis: 55.9" "Group enriched" "Detected in many" 13 "Early spermatids: 280.0;Late spermatids: 363.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055050 Approved Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA055050: AB_2682684" "unprognostic (3.49e-2)" "unprognostic (3.53e-1)" "unprognostic (2.69e-2)" "unprognostic (9.79e-2)" "unprognostic (3.26e-2)" "unprognostic (4.02e-2)" "prognostic unfavorable (5.17e-6)" "unprognostic (2.78e-1)" "unprognostic (1.43e-2)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (8.84e-3)" "unprognostic (1.14e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (3.71e-2)" 7.1 8.6 13.6 6.9 14.7 2.6 8.3 17.5 17.0 9.1 9.3 6.2 5.4 10.3 7.4 11.5 7.6 7.6 13.8 15.3 13.6 8.2 6.4 6.2 9.9 11.7 12.7 10.7 9.8 19.2 0.6 7.9 12.4 8.0 5.3 11.5 8.4 8.3 89.7 10.1 4.9 9.3 12.5 7.9 6.1 55.9 13.7 12.0 11.7 39.1 10.4 9.6 0.5 13.4 26.9 16.6 11.9 28.0 27.0 22.7 13.1 13.4 16.6 15.9 18.5 10.5 14.6 22.2 15.1 15.9 31.8 19.2 18.2 11.3 20.6 15.5 11.7 7.3 10.0 12.6 29.2 13.5 10.8 12.7 37.5 11.9 28.5 15.3 15.0 16.4 14.6 20.7 13.9 20.9 8.4 24.7 27.8 14.0 21.4 21.6 17.9 18.7 14.7 9.6 12.1 21.0 18.8 23.0 28.6 23.9 22.1 34.9 11.4 12.5 28.5 20.6 17.5 19.7 37.2 23.2 14.6 24.1 39.3 6.6 4.2 8.0 4.7 3.5 4.4 9.1 5.4 6.5 7.7 7.7 8.4 6.8 2.0 12.9 3.8 6.8 6.6 3.7 13.6 14.7 17.5 17.0 15.3 13.6 11.7 12.7 12.4 12.5 13.7 13.4 4.1 3.2 1.1 1.3 8.1 7.8 4.9 6.2 12.0 2.9 6.0 6.9 9.2 0.0 8.2 1.8 6.2 6.3 5.4 3.8 1.9 4.9 280.0 6.0 5.5 4.6 6.1 7.8 4.7 4.8 7.5 6.8 7.7 4.8 1.3 4.4 6.4 3.5 6.2 0.0 4.7 4.2 4.1 6.8 10.5 363.4 8.4 7.4 3.6 2.8 7.1 5.2 6.2 4.0 3.9 4.8 2.1 13.2 3.9 5.5 3.3 2.8 3.4 2.3 0.0 6.3 5.4 23.7 11.4 10.3 10.1 8.2 5.2 3.9 3.4 6.7 FAM221B C9orf128 ENSG00000204930 "Family with sequence similarity 221 member B" A6H8Z2 9 35816391-35828747 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 2.9;testis: 9.8" "Group enriched" "Detected in some" 12 "Early spermatids: 266.3;Late spermatids: 122.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA026577 Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA026577: AB_1845810" "unprognostic (1.23e-1)" "unprognostic (5.32e-2)" "unprognostic (9.40e-2)" "unprognostic (3.59e-2)" "unprognostic (1.25e-1)" "unprognostic (9.81e-3)" "unprognostic (6.94e-2)" "unprognostic (2.44e-2)" "unprognostic (4.03e-1)" "unprognostic (2.67e-2)" "unprognostic (3.13e-3)" "unprognostic (4.22e-1)" "unprognostic (9.20e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-1)" "unprognostic (3.15e-2)" "unprognostic (1.25e-3)" 0.1 0.1 0.2 0.4 0.3 2.9 0.4 1.2 0.4 0.2 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.3 0.2 0.2 0.1 0.0 0.1 0.2 0.5 0.5 0.2 0.1 0.1 0.1 0.1 0.0 0.5 0.7 0.5 0.6 0.5 0.0 0.3 0.2 0.0 0.1 0.3 0.3 0.4 9.8 0.3 0.2 0.1 0.0 0.5 0.2 0.0 0.6 0.0 0.2 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.2 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.9 0.0 0.0 2.9 0.1 0.0 0.2 0.3 1.2 0.4 0.2 0.1 0.5 0.2 0.5 0.3 0.3 0.6 0.0 0.0 3.1 0.3 0.4 0.0 0.4 1.0 0.0 4.1 0.8 0.4 0.4 0.0 1.8 0.0 0.0 0.1 16.1 0.3 0.0 0.1 266.3 0.5 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.0 0.4 1.2 2.0 0.3 0.0 122.0 2.1 0.4 0.0 0.0 0.2 1.9 0.0 1.0 0.7 0.2 1.6 0.7 0.3 1.3 0.0 0.1 2.7 5.5 0.0 0.1 0.2 6.0 1.4 0.0 0.0 0.0 0.0 0.1 0.2 1.3 FAM83C "C20orf128, dJ614O4.7" ENSG00000125998 "Family with sequence similarity 83 member C" Q9BQN1 20 35285731-35292425 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 33.3;skin 1: 42.3;vagina: 15.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 27.9;Basal squamous epithelial cells: 17.6;Early spermatids: 11.8;Squamous epithelial cells: 26.1;Suprabasal keratinocytes: 64.2" "Cancer enhanced" "Detected in some" "cervical cancer: 9.9;head and neck cancer: 18.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034227, HPA049978" Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB034227: AB_1562876, HPA049978: AB_2680979" "unprognostic (3.76e-2)" "unprognostic (2.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (3.61e-1)" "unprognostic (1.57e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (9.17e-5)" "unprognostic (9.89e-3)" "unprognostic (1.71e-1)" "unprognostic (5.01e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.0 0.2 5.3 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 4.2 0.0 0.1 42.3 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 2.1 0.6 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 27.9 1.1 0.0 17.6 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.8 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.2 6.5 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.3 1.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 26.1 64.2 0.0 0.0 0.0 0.1 1.9 FAM83E FLJ20200 ENSG00000105523 "Family with sequence similarity 83 member E" Q2M2I3 19 48599961-48615076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;salivary gland: 28.5;stomach 1: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 22.8;Early spermatids: 26.0;Gastric mucus-secreting cells: 74.9;Intestinal goblet cells: 26.9;Paneth cells: 16.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "CAPAN-2: 2.9;OE19: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049305, HPA075968" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol Vesicles "HPA049305: AB_2680705, HPA075968: " "unprognostic (1.36e-1)" "unprognostic (9.81e-3)" "unprognostic (3.83e-2)" "unprognostic (7.39e-2)" "unprognostic (4.77e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (2.26e-2)" "unprognostic (3.18e-1)" "unprognostic (2.71e-1)" "unprognostic (8.00e-2)" "unprognostic (9.31e-2)" "unprognostic (7.05e-8)" "unprognostic (5.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.70e-1)" "unprognostic (8.90e-3)" 0.1 0.1 0.2 3.7 0.3 0.4 1.4 0.8 0.5 10.6 0.2 32.7 30.0 1.1 0.1 7.0 3.9 6.4 0.2 0.3 0.2 0.8 0.3 8.0 0.2 0.1 0.1 0.0 1.2 0.0 0.2 0.6 0.2 3.2 16.6 0.2 28.5 0.4 2.7 1.9 30.0 1.0 0.0 0.2 37.4 2.2 0.2 0.1 0.1 0.0 1.3 1.2 4.1 0.5 0.4 0.4 0.0 0.7 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 2.9 0.5 0.2 0.1 0.0 0.5 0.1 0.0 0.0 0.4 0.1 0.1 0.3 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.8 1.1 9.4 0.9 0.2 0.1 0.3 0.0 0.2 0.5 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.2 0.5 0.1 0.1 0.2 0.1 1.0 0.1 0.2 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.2 0.6 0.1 0.1 0.1 0.0 0.0 0.2 0.3 0.8 0.5 0.3 0.2 0.1 0.1 0.2 0.0 0.2 0.5 0.0 9.6 13.4 1.3 0.4 0.0 1.4 0.8 0.6 0.0 1.8 0.8 2.1 8.6 6.5 1.8 0.0 0.1 0.3 22.8 0.0 0.1 26.0 4.8 0.5 0.2 5.4 0.0 0.3 1.1 0.1 0.2 74.9 5.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 26.9 2.0 0.0 0.0 9.3 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 1.6 16.5 0.0 0.4 3.3 12.7 0.0 5.1 0.0 0.0 0.2 0.2 0.8 0.5 2.3 0.0 0.1 0.3 0.1 12.8 6.9 FAM83G "FLJ41564, PAWS1" ENSG00000188522 "Family with sequence similarity 83 member G" A6ND36 17 18968789-19004764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.3;skin 1: 67.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 77.8;Basal squamous epithelial cells: 39.3;Distal enterocytes: 46.5;Squamous epithelial cells: 55.3;Suprabasal keratinocytes: 68.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA023369, HPA023940" Enhanced Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA023369: AB_1848415, HPA023940: AB_1848416" "unprognostic (2.12e-2)" "unprognostic (5.90e-2)" "unprognostic (1.17e-1)" "unprognostic (9.48e-2)" "unprognostic (1.42e-3)" "unprognostic (2.04e-2)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.07e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-2)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (5.65e-2)" "prognostic favorable (7.58e-6)" "unprognostic (9.68e-2)" "unprognostic (5.13e-2)" "unprognostic (3.74e-2)" 2.3 2.2 0.8 2.9 0.8 1.4 2.8 0.8 1.2 10.8 2.1 8.2 10.8 2.5 0.9 51.3 1.6 6.4 17.2 0.8 1.9 7.1 21.7 3.2 3.0 1.6 1.4 1.4 9.5 6.4 4.3 0.7 2.7 3.5 5.3 0.2 10.9 2.2 6.9 67.3 11.3 1.5 0.9 2.0 9.8 1.0 1.4 3.7 5.6 0.8 5.7 2.5 17.0 0.7 24.7 22.4 0.2 0.0 0.7 2.0 35.9 25.2 11.0 21.0 15.7 28.7 8.8 16.1 15.1 16.7 17.1 28.6 3.6 21.1 9.6 13.2 8.1 0.4 11.2 15.9 15.3 2.9 7.9 2.8 38.9 13.6 22.3 7.9 7.6 2.5 7.7 0.5 6.0 15.0 0.7 6.0 11.0 34.1 0.1 0.1 0.0 7.8 10.1 6.2 11.2 0.0 8.7 5.3 1.5 29.1 9.2 3.6 14.2 12.9 21.6 6.1 29.8 2.2 4.0 4.1 10.1 0.1 8.6 1.1 0.0 0.0 0.7 0.0 0.3 0.3 0.4 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.8 0.8 0.8 1.2 0.8 1.9 1.6 1.4 2.7 0.9 1.4 0.7 0.6 3.2 2.2 0.0 2.5 77.8 12.2 9.9 39.3 0.2 7.1 2.9 5.1 11.5 6.3 7.3 0.0 0.4 0.7 46.5 0.0 15.8 0.1 2.4 1.0 1.9 7.1 2.7 0.1 10.0 9.7 2.6 17.3 5.0 8.9 3.5 1.1 20.9 1.2 0.0 0.1 17.7 8.2 0.3 7.8 1.9 0.0 1.0 5.4 0.0 1.0 0.2 3.1 0.5 0.0 24.3 22.8 0.0 3.0 13.2 15.3 4.4 2.5 0.4 0.0 1.3 2.0 0.1 1.0 55.3 68.5 1.9 2.6 0.0 17.1 9.1 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.2;testis: 21.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 44.1;Spermatogonia: 38.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 1.4 1.9 1.7 6.7 1.9 20.2 1.9 2.4 3.3 2.1 1.5 5.5 5.2 1.2 0.8 6.6 2.0 1.2 1.6 1.8 1.2 2.9 6.1 3.4 12.5 1.4 1.1 1.4 1.9 1.4 1.9 4.1 1.5 1.7 6.2 1.0 2.1 0.6 0.7 5.2 5.6 2.1 1.1 6.7 3.6 21.6 1.5 8.1 1.7 0.6 13.5 2.2 2.7 1.9 23.2 34.8 40.8 35.7 2.6 5.2 31.2 28.2 15.3 46.5 19.5 30.6 37.3 56.2 12.9 9.8 15.5 34.7 27.7 21.1 48.8 13.4 46.5 16.6 49.1 63.4 1.7 17.1 17.5 1.7 2.2 37.8 12.0 6.6 14.9 28.0 40.9 16.9 24.6 53.6 34.6 73.7 26.5 31.5 21.3 61.4 32.8 10.3 11.8 21.5 36.3 19.7 41.9 12.3 5.4 23.3 22.4 30.4 11.1 37.0 38.9 20.9 30.0 15.1 19.0 56.3 17.5 37.8 36.1 2.5 7.4 9.9 4.2 8.5 3.0 7.0 2.4 3.7 6.2 4.6 0.6 2.6 9.4 8.2 9.2 0.4 9.2 4.2 1.7 1.9 2.4 3.3 1.8 1.2 1.4 1.1 1.5 1.1 1.5 1.9 1.5 0.0 1.1 0.7 9.6 3.4 1.6 2.6 0.0 8.1 3.0 2.0 2.9 0.0 3.5 16.5 10.4 16.0 12.3 5.1 1.9 2.0 5.9 2.8 3.5 2.1 1.8 20.8 10.0 1.6 9.9 3.3 9.2 3.4 2.5 19.0 5.3 4.7 8.8 3.3 5.7 8.1 2.0 4.1 3.1 4.1 1.5 6.8 0.0 1.0 3.0 1.1 21.6 3.0 1.7 1.9 1.7 0.0 21.1 1.3 6.6 10.4 6.4 7.7 0.0 2.7 3.5 44.1 38.5 3.8 1.8 25.3 9.3 6.8 11.4 2.6 FANCI "FLJ10719, KIAA1794" ENSG00000140525 "FA complementation group I" Q9NVI1 15 89243945-89317261 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.4;lymphoid tissue: 44.2;testis: 32.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.6;Spermatocytes: 69.5;Spermatogonia: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 23.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039972, HPA040379" Approved Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039972: AB_10673265, HPA040379: AB_2676951" "unprognostic (6.88e-2)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (2.99e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.82e-3)" "unprognostic (1.15e-2)" "unprognostic (4.59e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.71e-13)" "unprognostic (2.40e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" 3.2 2.1 1.6 13.0 1.3 31.4 6.0 3.8 2.5 3.3 0.0 10.5 6.0 4.7 1.1 8.1 3.4 3.0 1.7 1.7 0.7 1.7 2.9 3.4 23.9 1.2 0.9 3.8 3.0 3.0 0.6 11.3 1.7 3.6 12.4 5.4 2.8 2.0 0.8 8.0 7.3 6.9 0.6 6.0 6.7 32.6 1.3 44.2 2.0 0.8 26.6 5.4 3.7 1.7 108.2 122.4 127.8 86.1 10.8 16.0 78.5 101.4 58.3 123.6 150.5 96.8 95.4 198.8 53.4 33.8 79.3 143.9 196.8 69.0 116.2 127.8 123.5 197.2 176.7 45.8 1.7 146.0 96.3 8.6 6.8 87.1 44.4 17.6 51.7 120.2 139.2 142.3 83.5 61.5 150.9 49.6 101.1 70.3 44.5 130.6 187.1 84.6 28.5 196.8 93.9 80.8 105.2 73.3 46.7 85.7 81.2 64.8 35.4 103.2 103.8 94.9 155.8 93.3 209.5 151.9 38.5 125.7 104.7 23.4 2.3 3.0 4.7 3.0 2.8 3.5 4.7 6.5 2.2 3.6 3.3 5.6 3.1 5.1 4.3 4.1 11.8 3.1 1.6 1.3 3.8 2.5 1.7 0.7 1.2 0.9 1.7 0.6 1.3 1.7 2.6 3.2 1.5 3.6 3.8 4.2 2.6 4.0 0.6 2.4 2.9 2.7 3.9 0.0 3.3 1.8 0.0 17.0 3.9 4.2 0.0 2.0 7.9 5.0 3.7 3.0 1.2 48.6 7.0 2.9 18.3 3.9 5.6 4.5 2.5 14.9 6.8 0.8 8.1 1.7 5.8 5.9 0.0 3.0 3.8 7.9 3.4 4.8 1.8 1.9 3.3 11.6 1.0 9.0 6.9 2.5 1.2 1.5 13.9 2.0 1.3 1.0 6.3 1.9 6.6 3.6 4.0 69.5 60.2 9.2 2.4 12.4 8.1 2.5 9.1 2.8 FAR1 "FLJ22728, MLSTD2, SDR10E1" ENSG00000197601 "Fatty acyl-CoA reductase 1" Q8WVX9 11 13668668-13732346 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Cataract, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 437.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017322 Approved Supported Peroxisomes NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 15: RT4 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Peroxisomes "HPA017322: AB_1848424" "unprognostic (3.96e-2)" "unprognostic (1.92e-1)" "prognostic favorable (2.27e-4)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (4.62e-2)" "unprognostic (3.66e-1)" "unprognostic (3.30e-1)" "unprognostic (2.79e-1)" "unprognostic (3.60e-2)" "unprognostic (2.59e-2)" "unprognostic (1.84e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (2.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-3)" 21.1 16.2 19.3 23.0 36.0 74.9 20.6 34.3 31.5 23.8 24.5 32.9 38.7 24.7 24.9 50.9 17.7 13.7 20.0 22.6 29.7 14.0 5.0 20.2 20.5 48.4 29.9 19.9 21.3 29.1 15.6 24.6 44.1 20.5 37.6 32.6 18.2 15.4 15.2 12.2 21.1 30.7 37.3 20.5 62.0 20.8 32.1 16.5 19.8 18.6 23.9 28.4 30.0 94.8 79.5 50.6 49.1 38.4 45.9 52.6 26.7 69.2 27.6 50.0 52.7 53.5 66.4 100.9 30.2 55.5 74.3 84.3 73.2 69.9 76.1 30.0 59.4 43.4 44.8 0.2 44.1 87.9 33.7 40.2 70.3 36.2 107.7 36.9 49.6 50.2 68.9 29.3 41.5 39.9 65.5 26.3 25.8 100.1 72.6 56.9 62.6 28.4 48.4 126.4 37.7 27.3 65.5 61.6 34.4 56.2 37.8 54.1 62.1 68.5 58.2 63.7 58.4 16.4 59.6 84.7 43.4 26.4 42.4 10.4 24.9 28.0 7.7 21.3 5.4 3.5 3.7 6.6 28.5 5.5 3.3 5.5 38.9 9.1 18.2 4.4 5.3 7.7 19.3 36.0 34.3 31.5 22.6 29.7 48.4 29.9 44.1 37.3 32.1 94.8 38.6 35.3 21.1 80.0 24.2 32.2 24.2 21.5 41.5 46.0 27.6 20.3 24.1 5.7 26.2 22.0 41.7 25.7 40.2 59.8 5.9 12.8 100.8 21.1 36.5 31.4 36.0 38.5 146.0 25.9 18.5 26.8 114.7 26.2 38.7 23.3 29.6 2.5 33.9 47.1 113.5 28.8 26.4 53.5 57.0 181.3 26.8 48.8 35.6 71.2 54.8 20.6 20.6 93.5 437.2 29.3 43.4 25.6 36.1 30.8 23.3 8.7 18.7 50.4 26.3 29.3 29.3 41.6 32.3 116.9 19.9 9.9 25.8 17.0 47.7 42.0 FARP1 "CDEP, MGC87400, PLEKHC2, PPP1R75" ENSG00000152767 "FERM, ARH/RhoGEF and pleckstrin domain protein 1" Q9Y4F1 13 98142562-98455176 "Predicted intracellular proteins" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 191.3;Early spermatids: 207.8;Inhibitory neurons: 176.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 125.3;Hep G2: 130.5;SuSa: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000760 Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "HPA000760: AB_1078816" "unprognostic (4.78e-3)" "unprognostic (1.65e-1)" "unprognostic (3.07e-1)" "unprognostic (2.01e-1)" "unprognostic (1.10e-2)" "unprognostic (2.30e-1)" "unprognostic (7.73e-2)" "unprognostic (6.91e-2)" "unprognostic (1.03e-1)" "unprognostic (6.09e-2)" "unprognostic (3.13e-1)" "unprognostic (1.08e-1)" "prognostic favorable (1.39e-5)" "unprognostic (4.89e-2)" "unprognostic (2.27e-1)" "unprognostic (2.18e-2)" "unprognostic (4.18e-2)" 17.9 35.3 40.7 10.1 43.9 1.5 24.4 24.9 40.8 26.4 18.7 41.8 8.0 19.8 23.7 8.9 18.4 18.5 13.7 42.5 37.9 68.7 67.8 32.8 6.9 35.5 35.3 16.2 45.0 14.2 23.1 28.2 30.2 41.2 12.6 8.9 37.2 25.7 19.7 14.0 13.6 23.4 35.6 13.0 32.9 14.0 38.9 3.3 43.9 15.1 3.7 27.0 16.1 28.6 0.7 10.7 47.1 66.7 13.3 26.0 22.7 72.0 46.9 39.8 34.8 83.9 31.9 0.2 27.0 125.3 9.8 1.5 20.1 19.9 66.4 1.3 20.5 0.4 38.9 130.5 35.3 0.3 0.6 30.6 8.9 11.6 2.6 23.0 26.5 1.0 0.1 0.7 27.8 18.6 2.8 0.4 22.5 40.7 12.5 25.4 18.3 1.4 88.0 46.8 20.0 43.5 8.8 18.9 51.0 110.8 26.9 0.1 25.6 42.8 16.1 29.2 37.0 0.7 0.7 0.5 19.9 1.4 30.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.7 43.9 24.9 40.8 42.5 37.9 35.5 35.3 30.2 35.6 38.9 28.6 37.3 44.8 24.8 191.3 2.6 6.9 60.2 8.8 15.4 13.9 73.3 40.8 8.4 123.0 27.5 57.0 45.9 6.7 4.0 10.9 80.3 47.5 207.8 70.3 90.5 23.9 31.1 2.7 75.3 35.1 6.4 29.9 23.4 100.7 13.3 44.5 23.2 58.4 53.5 30.3 176.4 10.1 24.4 22.7 9.3 125.9 19.0 14.0 28.4 44.0 17.5 29.6 2.1 104.5 3.7 47.0 4.4 29.3 3.1 56.8 0.3 139.6 38.6 15.7 19.7 18.7 55.4 9.2 15.9 3.2 2.8 4.5 6.4 60.4 12.6 47.2 FAXC "C6orf168, dJ273F20, MGC2817" ENSG00000146267 "Failed axon connections homolog, metaxin like GST domain containing" Q5TGI0 6 99271168-99350062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Excitatory neurons: 57.1;Inhibitory neurons: 60.1;Oligodendrocyte precursor cells: 43.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 26.0;HAP1: 23.8;SCLC-21H: 34.2;SH-SY5Y: 23.7;SK-MEL-30: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039106 Uncertain Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA039106: AB_10697546" "unprognostic (8.03e-2)" "unprognostic (4.91e-2)" "unprognostic (5.04e-3)" "unprognostic (6.44e-2)" "unprognostic (3.80e-1)" "unprognostic (5.00e-3)" "unprognostic (7.56e-2)" "unprognostic (7.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.34e-2)" "unprognostic (2.79e-3)" "unprognostic (2.47e-3)" "unprognostic (6.70e-4)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.86e-2)" "unprognostic (3.49e-3)" 0.7 2.2 11.0 1.5 12.7 0.0 3.2 9.3 19.0 2.5 2.0 22.7 1.5 6.5 11.0 6.2 3.7 2.4 0.8 14.1 7.6 2.7 0.0 1.7 0.1 7.2 5.6 2.2 2.5 6.5 15.9 0.8 6.3 8.2 2.9 10.4 7.4 10.6 0.5 0.9 3.3 7.8 4.4 0.4 7.1 2.1 8.5 2.2 1.7 0.6 0.1 14.3 2.9 11.4 4.0 3.2 10.3 14.3 0.0 0.0 3.8 5.0 3.2 8.1 7.0 1.9 1.3 0.0 0.6 1.0 26.0 0.1 23.8 4.7 7.0 0.0 11.8 0.1 1.9 0.7 0.6 0.0 0.0 0.5 7.5 0.2 3.8 5.9 0.0 2.0 0.5 0.0 2.7 7.0 0.0 0.0 12.2 0.0 4.8 0.0 1.0 0.0 4.3 0.3 34.2 23.7 4.5 3.2 22.6 4.2 10.0 0.0 1.0 2.5 4.7 0.0 15.5 0.0 0.0 0.0 0.1 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 12.7 9.3 19.0 14.1 7.6 7.2 5.6 6.3 4.4 8.5 11.4 0.2 25.6 15.2 5.5 0.5 0.4 4.2 4.2 5.7 14.4 5.3 9.0 1.1 0.0 8.1 1.8 10.4 1.2 0.4 0.2 9.8 2.3 2.6 0.6 1.0 1.7 0.0 0.0 57.1 0.7 0.2 1.4 0.0 0.4 3.8 0.4 1.4 0.1 0.2 3.3 60.1 0.2 4.1 0.6 1.1 5.0 0.0 1.2 1.8 2.8 0.1 3.6 2.1 43.7 4.4 1.0 0.1 1.9 0.1 4.8 0.0 1.0 2.1 13.6 0.0 0.2 1.3 1.3 8.9 1.2 0.3 0.3 1.2 0.2 0.4 1.2 FBLIM1 "CAL, FBLP-1, migfilin" ENSG00000162458 "Filamin binding LIM protein 1" Q8WUP2 1 15756607-15786594 "Predicted intracellular proteins" "Cell adhesion, Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.3;Paneth cells: 153.6;Peritubular cells: 191.5;Proximal enterocytes: 145.9;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 255.9;TIME: 420.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025287, HPA072750" Approved Enhanced "Nucleoli fibrillar center,Cell Junctions,Focal adhesion sites" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions, Focal adhesion sites" "Nucleoli fibrillar center" "HPA025287: AB_1848443, HPA072750: AB_2686554" "unprognostic (4.10e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (2.26e-1)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.33e-2)" "unprognostic (8.77e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (2.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.33e-2)" "unprognostic (3.01e-1)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 32.4 17.9 2.7 21.5 3.3 0.8 28.1 3.2 4.8 43.2 5.2 75.6 82.2 75.7 15.6 24.1 43.5 69.8 45.6 2.5 2.4 26.7 7.1 39.3 9.6 2.6 3.2 39.1 27.5 36.2 11.0 29.4 2.9 47.0 53.2 1.8 31.7 63.1 5.4 16.8 86.1 47.1 2.5 27.6 64.0 12.8 3.8 2.8 17.6 5.6 6.8 44.6 29.3 2.6 34.2 17.2 15.9 0.6 3.7 8.1 21.6 55.2 84.3 38.4 30.4 6.0 48.8 0.3 114.5 87.8 67.3 62.5 11.3 121.0 19.2 0.3 6.6 0.2 4.7 31.7 98.5 0.2 0.6 39.7 81.7 31.9 75.1 82.7 255.9 2.0 1.2 7.6 13.2 0.8 0.6 1.1 16.5 50.9 25.0 0.1 0.4 1.0 51.4 22.1 0.2 38.9 29.0 3.4 6.0 33.9 6.8 0.6 420.4 50.7 7.1 0.8 25.7 0.4 1.0 0.5 8.0 0.2 0.5 1.7 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.5 0.3 0.3 0.8 0.4 0.2 0.4 0.1 0.1 2.7 3.3 3.2 4.8 2.5 2.4 2.6 3.2 2.9 2.5 3.8 2.6 10.8 12.8 18.1 0.0 3.1 86.3 82.7 41.4 20.5 3.7 28.6 23.9 37.1 47.1 30.6 16.5 6.2 8.9 4.8 207.3 0.0 99.1 3.4 13.6 75.9 19.2 46.0 0.0 0.7 53.5 114.2 29.3 133.5 20.5 18.9 9.4 55.0 2.5 5.6 1.7 5.5 54.8 26.4 1.9 23.5 4.0 80.2 5.8 14.2 2.8 2.7 9.1 1.0 1.0 1.2 113.0 153.6 191.5 1.2 29.8 145.9 2.5 11.6 6.4 144.7 11.9 64.8 2.8 1.9 17.4 62.8 19.4 6.0 6.6 53.8 62.6 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.4;Fibroblasts: 388.5;Leydig cells: 236.1;Oligodendrocytes: 218.7;Peritubular cells: 227.2;Skeletal myocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 215.1;ASC TERT1: 460.7;fHDF/TERT166: 420.8;HSkMC: 251.3;hTERT-RPE1: 211.1;U-138 MG: 206.9;U-2197: 305.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" 60.9 4.4 1.4 14.5 5.4 3.4 13.7 2.8 2.8 36.0 9.5 8.3 3.8 15.2 6.3 12.6 12.2 27.3 23.5 0.8 2.0 2.7 2.9 10.0 3.7 5.2 6.0 28.4 3.3 3.0 2.5 76.7 3.7 8.0 11.7 1.3 4.6 13.2 4.5 5.7 6.6 35.7 2.3 6.4 6.0 7.1 4.7 2.9 18.6 21.2 3.5 18.8 9.9 5.0 0.1 5.2 19.8 22.4 215.1 460.7 0.2 175.8 62.9 51.1 32.4 0.1 0.3 0.1 7.9 420.8 0.4 0.7 3.9 0.6 45.9 20.7 1.2 2.0 88.5 0.2 120.7 0.8 0.3 251.3 0.1 135.9 15.6 211.1 55.5 1.6 0.0 0.4 55.6 0.0 1.5 0.2 4.0 0.2 7.1 0.1 17.0 0.2 5.9 0.5 0.2 12.9 0.0 2.2 0.1 15.3 0.2 1.4 106.8 206.9 6.2 305.8 37.6 1.2 1.0 0.0 138.9 0.3 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 5.4 2.8 2.8 0.8 2.0 5.2 6.0 3.7 2.3 4.7 5.0 50.0 0.0 1.3 34.9 0.4 25.6 0.8 1.5 0.6 6.1 1.3 3.4 14.2 0.0 5.8 12.9 0.0 132.4 0.4 0.0 0.0 0.2 8.7 4.2 105.2 36.1 0.0 5.5 82.3 0.6 40.8 388.5 3.1 2.0 1.3 22.5 34.6 0.6 15.3 0.0 123.5 0.0 0.0 0.8 39.0 22.8 236.1 5.7 42.7 30.0 2.3 0.8 0.0 76.9 218.7 1.7 0.0 227.2 1.7 0.7 0.1 0.6 3.3 0.2 26.3 139.5 55.8 3.3 3.4 0.8 20.6 65.8 4.3 51.3 0.0 0.2 FBXO16 FBX16 ENSG00000214050 "F-box protein 16" Q8IX29 8 28348287-28490278 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 18.4;pituitary gland: 17.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Excitatory neurons: 44.4;Inhibitory neurons: 43.6;Rod photoreceptor cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 9.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 9.6" "Cell line enhanced" "Detected in many" "AF22: 20.3;Karpas-707: 22.4" "Low region specificity" "Detected in all" "HPA058676, HPA076472" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Plasma membrane, Cytosol" "HPA058676: AB_2683795, HPA076472: " "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (3.37e-3)" "unprognostic (5.56e-3)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (4.95e-3)" "unprognostic (6.49e-2)" "prognostic favorable (6.70e-5)" "unprognostic (3.41e-3)" "unprognostic (4.90e-2)" "unprognostic (7.15e-2)" "unprognostic (1.71e-2)" "unprognostic (4.85e-2)" "unprognostic (2.72e-2)" "unprognostic (2.07e-1)" 0.5 1.8 3.9 0.9 5.0 2.2 2.6 6.8 7.0 4.1 2.9 1.6 2.0 1.1 18.4 0.7 4.4 1.4 1.4 4.6 3.9 3.2 6.0 1.5 1.4 1.1 1.7 0.7 4.7 7.1 17.3 0.6 2.0 3.5 2.0 14.3 3.4 5.1 1.1 0.4 2.9 0.7 0.3 1.2 2.2 4.2 3.5 0.6 7.0 0.9 2.8 1.2 0.7 4.3 16.5 2.9 20.3 7.5 0.5 0.0 0.3 0.2 0.5 3.0 5.5 3.1 4.6 5.8 7.2 0.1 8.1 5.1 2.3 3.5 3.0 2.6 3.6 2.7 0.3 1.7 0.0 3.5 1.9 0.2 10.8 0.7 3.2 1.5 0.0 5.6 1.1 22.4 1.0 5.7 0.5 5.0 3.9 2.2 4.5 0.2 4.5 8.2 3.9 2.4 13.1 5.4 0.4 3.3 9.5 3.5 13.8 5.9 0.6 1.6 5.8 3.2 3.0 5.2 5.0 5.2 6.8 0.7 3.5 0.3 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.2 0.1 0.2 0.9 0.0 0.1 9.6 0.2 0.1 3.9 5.0 6.8 7.0 4.6 3.9 1.1 1.7 2.0 0.3 3.5 4.3 0.0 3.2 4.1 7.5 1.7 0.1 3.0 10.9 5.2 8.2 3.9 3.4 2.1 8.6 7.9 3.7 35.5 0.6 0.0 0.5 7.9 5.3 12.1 13.5 1.3 0.2 10.2 0.0 44.4 4.6 0.4 0.9 1.5 6.4 0.0 1.9 0.4 1.9 2.7 5.0 43.6 3.9 4.1 0.8 2.3 12.4 1.2 0.4 0.0 2.8 0.0 9.3 0.0 23.6 3.2 3.1 0.4 0.7 11.1 1.7 0.2 4.7 23.4 48.6 0.0 0.5 1.8 10.5 5.6 1.2 0.0 0.0 0.5 4.2 1.0 1.7 FBXO27 "Fbg5, Fbx27" ENSG00000161243 "F-box protein 27" Q8NI29 19 38990714-39032785 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 37.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.1;Suprabasal keratinocytes: 17.8;Syncytiotrophoblasts: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 35.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA046800, HPA062242" Approved Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA046800: AB_2679813, HPA062242: AB_2684723" "prognostic favorable (2.15e-4)" "unprognostic (7.32e-2)" "unprognostic (2.03e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (1.48e-3)" "unprognostic (4.38e-3)" "unprognostic (1.02e-1)" "unprognostic (8.95e-2)" "unprognostic (1.67e-1)" "unprognostic (7.31e-3)" "unprognostic (6.80e-2)" "unprognostic (9.31e-2)" "unprognostic (2.25e-2)" "unprognostic (8.72e-3)" "unprognostic (6.04e-2)" "unprognostic (7.51e-2)" "unprognostic (3.21e-2)" 13.3 3.7 17.5 2.1 15.9 2.7 6.2 23.8 18.7 6.3 6.4 6.8 2.2 4.7 2.4 15.4 5.3 5.5 19.6 15.4 8.9 6.4 7.5 3.2 3.7 10.7 6.7 10.2 4.8 2.5 4.1 3.8 9.1 8.9 8.7 4.9 7.4 7.8 1.6 37.5 4.9 7.4 4.9 3.1 3.8 4.7 11.1 4.0 4.6 2.4 4.0 7.7 9.7 13.1 9.1 11.4 0.3 7.2 15.3 0.8 3.3 1.2 6.7 5.2 4.9 3.8 3.4 0.9 17.5 10.3 9.0 15.5 0.6 6.6 3.4 0.8 0.4 0.3 3.0 0.6 2.7 0.9 2.5 5.5 10.2 5.4 0.4 8.2 3.3 0.4 5.4 1.2 7.2 8.1 0.6 1.4 8.1 3.0 20.4 0.2 0.1 1.1 3.4 35.3 0.4 10.8 17.7 2.2 0.1 4.8 9.2 1.7 4.0 0.5 0.4 0.3 0.9 3.5 8.9 1.9 9.0 0.2 0.3 1.1 0.3 0.2 0.3 0.3 0.2 0.4 0.2 0.2 0.2 0.6 0.4 0.3 1.7 1.7 0.2 0.5 0.3 0.2 17.5 15.9 23.8 18.7 15.4 8.9 10.7 6.7 9.1 4.9 11.1 13.1 0.2 3.2 15.0 2.3 0.1 5.9 4.1 1.4 9.1 7.5 3.8 4.2 9.5 7.2 6.4 1.8 0.0 36.1 0.5 0.2 1.9 1.5 3.7 1.9 3.6 3.2 0.0 0.0 4.8 0.8 4.8 2.7 6.1 1.6 7.6 2.3 1.4 3.2 4.9 8.4 4.6 0.2 8.2 0.3 4.9 2.5 2.8 2.1 0.0 1.0 1.1 5.6 0.0 3.0 4.1 0.3 0.0 4.1 1.9 2.3 6.9 7.3 4.7 3.0 0.0 1.8 1.5 6.4 2.0 13.5 17.8 27.0 1.3 0.4 0.2 5.3 FBXO28 "CENP-30, Fbx28, FLJ10766, KIAA0483" ENSG00000143756 "F-box protein 28" Q9NVF7 1 224114111-224162047 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003289 Approved Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Focal adhesion sites" "HPA003289: AB_2666879" "unprognostic (4.91e-2)" "unprognostic (5.57e-2)" "unprognostic (1.78e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.12e-1)" "unprognostic (8.25e-2)" "unprognostic (2.03e-1)" "unprognostic (7.09e-2)" "unprognostic (5.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-2)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (2.61e-1)" 10.9 7.5 6.5 8.3 7.3 8.9 12.3 8.8 10.5 10.9 7.4 10.3 8.5 10.0 7.9 12.4 8.2 9.5 8.1 7.6 9.1 13.6 17.4 8.9 10.5 8.5 7.4 11.3 7.6 13.7 4.4 9.0 8.8 10.0 10.6 8.3 7.9 8.5 12.5 21.1 7.7 9.8 8.0 8.9 8.5 7.8 7.8 10.9 9.8 14.2 10.6 11.5 9.0 8.9 24.6 10.6 16.2 17.4 16.6 19.0 26.7 24.3 19.7 16.0 15.2 14.9 18.7 11.8 24.4 22.3 10.3 20.9 24.2 23.4 27.4 17.0 27.0 15.0 12.8 10.7 20.7 28.3 18.8 18.6 27.7 23.2 41.9 18.8 27.1 15.0 24.8 16.4 29.1 8.1 14.9 14.4 38.6 32.3 22.8 15.7 23.1 22.3 30.2 16.1 26.2 28.1 25.1 38.0 27.4 16.9 20.2 28.2 31.2 19.8 15.0 25.0 46.1 17.8 22.3 18.0 24.5 13.7 39.3 7.4 6.5 11.8 5.8 6.0 7.2 8.9 5.9 6.8 7.8 9.0 5.9 6.6 4.2 8.6 6.9 3.5 8.8 4.6 6.5 7.3 8.8 10.5 7.6 9.1 8.5 7.4 8.8 8.0 7.8 8.9 15.0 6.4 10.6 22.5 16.8 34.3 25.5 11.3 9.6 20.5 14.7 11.7 11.4 7.2 13.5 11.0 22.9 14.2 12.3 17.2 9.8 13.2 30.3 15.9 13.0 16.4 18.5 17.4 48.8 11.5 13.1 12.7 7.1 22.9 14.0 12.6 14.3 23.4 13.9 18.5 43.8 12.7 14.2 17.7 16.3 14.8 13.1 16.8 28.4 34.7 16.4 12.6 7.2 45.8 43.7 17.7 12.2 13.2 15.4 21.5 12.0 22.8 11.5 18.6 13.1 14.9 12.7 24.7 26.8 17.2 39.1 23.0 18.9 10.9 14.6 30.7 FBXO30 "Fbx30, MGC21674" ENSG00000118496 "F-box protein 30" Q8TB52 6 145793502-145814795 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 9.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012583 Approved Approved Microtubules NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 40: Granulosa cells - Unknown function" Microtubules "HPA012583: AB_2668686" "unprognostic (8.69e-2)" "unprognostic (3.35e-3)" "unprognostic (2.92e-2)" "unprognostic (4.29e-2)" "unprognostic (5.47e-3)" "unprognostic (8.36e-2)" "unprognostic (7.61e-7)" "unprognostic (5.79e-2)" "unprognostic (1.63e-1)" "unprognostic (6.32e-2)" "unprognostic (1.18e-2)" "unprognostic (9.25e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (5.72e-2)" "unprognostic (1.68e-1)" "unprognostic (1.78e-1)" 4.5 4.0 3.8 4.2 5.0 7.2 4.0 4.6 3.9 4.1 2.7 9.7 4.1 6.7 3.1 9.6 3.2 5.6 7.2 3.1 6.0 4.1 3.4 3.2 4.3 4.5 5.5 5.9 3.8 4.0 1.6 4.8 4.7 6.0 4.7 5.3 4.4 6.8 11.5 2.6 3.5 8.0 4.2 3.7 3.7 6.5 5.1 2.9 8.0 9.1 4.1 5.7 2.9 5.3 3.7 6.9 9.7 13.2 9.9 8.8 9.9 10.3 9.6 6.9 6.8 8.7 3.3 17.0 7.8 11.8 12.6 5.7 8.4 7.5 10.4 10.0 5.8 10.8 9.1 8.8 17.8 14.1 10.8 14.6 8.3 8.6 11.4 9.0 10.1 4.1 12.6 11.9 13.6 2.9 6.4 7.5 11.2 2.4 5.1 8.2 21.7 5.9 7.2 3.8 4.3 6.9 12.6 6.5 6.1 9.6 3.0 13.8 13.4 7.1 6.0 9.1 10.4 8.8 7.2 6.8 11.4 6.0 7.7 9.3 1.3 1.6 0.4 1.1 0.3 0.6 0.4 0.8 1.6 1.3 0.6 0.6 1.2 0.5 0.9 0.5 0.3 0.6 3.8 5.0 4.6 3.9 3.1 6.0 4.5 5.5 4.7 4.2 5.1 5.3 11.1 3.2 5.9 7.2 5.4 14.3 5.3 4.2 12.5 8.8 10.5 8.3 22.9 10.0 4.7 3.7 4.2 5.8 5.7 4.9 11.7 4.7 10.9 4.1 13.7 13.8 6.0 36.7 5.3 3.2 3.4 15.4 7.1 6.2 12.0 37.1 11.4 9.7 7.5 26.9 6.4 5.0 2.0 11.9 20.8 4.4 11.1 10.2 7.2 7.5 7.5 12.0 0.0 5.0 7.6 5.1 3.2 10.1 11.1 7.1 4.3 8.2 2.8 8.7 0.0 26.5 18.4 19.7 10.5 12.4 17.3 5.6 6.2 7.2 5.0 5.0 FBXO42 "Fbx42, KIAA1332" ENSG00000037637 "F-box protein 42" Q6P3S6 1 16246840-16352480 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025071 Approved Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA025071: AB_1848461" "unprognostic (1.08e-1)" "unprognostic (2.38e-1)" "unprognostic (1.25e-1)" "unprognostic (3.09e-2)" "unprognostic (1.40e-1)" "unprognostic (1.11e-2)" "prognostic unfavorable (3.72e-4)" "unprognostic (3.22e-2)" "unprognostic (4.00e-2)" "unprognostic (4.22e-2)" "unprognostic (3.96e-2)" "unprognostic (4.61e-2)" "unprognostic (1.22e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-1)" "unprognostic (5.78e-3)" "unprognostic (3.91e-2)" 14.1 12.6 17.4 8.8 16.4 9.3 12.9 20.0 18.0 21.7 14.7 15.1 7.6 19.8 12.9 18.2 18.6 11.8 16.9 16.5 17.6 11.8 14.2 13.6 12.5 16.9 16.3 18.2 15.3 14.0 16.2 12.1 17.8 19.3 10.6 16.7 13.5 15.0 22.6 28.1 11.1 17.9 14.9 13.7 12.1 11.6 16.8 18.1 14.6 22.3 14.3 18.9 17.9 16.4 15.4 8.2 19.4 19.8 23.1 15.0 8.5 15.6 23.5 22.0 21.4 7.7 13.9 16.2 13.6 21.7 15.1 13.6 19.8 14.8 17.9 18.7 9.3 15.2 12.5 8.8 27.5 18.1 19.0 16.1 33.5 19.4 27.8 20.0 22.3 20.0 16.5 22.1 15.8 10.5 17.5 15.8 8.5 20.3 9.2 19.6 11.9 14.5 14.8 4.3 18.3 12.0 17.6 14.6 18.8 17.7 11.9 14.0 14.0 11.1 9.8 18.4 12.3 10.9 11.9 16.3 14.7 23.5 15.6 9.0 11.8 18.5 11.7 16.3 8.7 8.5 8.7 7.5 14.0 14.1 9.8 8.7 10.5 12.4 12.7 6.1 12.4 7.9 17.4 16.4 20.0 18.0 16.5 17.6 16.9 16.3 17.8 14.9 16.8 16.4 9.2 12.8 11.8 47.0 16.0 25.9 6.1 13.5 22.2 21.7 7.1 7.1 20.6 15.7 9.4 12.9 45.9 11.0 16.6 6.7 0.0 8.5 9.4 21.7 15.5 9.9 10.7 10.8 63.9 7.6 15.6 14.7 11.7 33.1 2.5 12.8 9.7 9.6 13.8 28.6 65.9 5.6 10.2 15.1 28.1 10.2 14.9 13.4 1.8 35.6 19.2 11.0 15.5 60.8 53.0 8.4 7.6 11.3 17.7 10.4 8.8 3.8 6.4 20.4 13.1 23.1 13.4 13.5 9.7 18.9 34.7 26.3 16.0 9.8 8.3 5.5 FBXO48 ENSG00000204923 "F-box protein 48" Q5FWF7 2 68459422-68467294 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Alveolar cells type 2: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA049775, HPA054782" Uncertain Approved "Nuclear bodies" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 54: Non-specific - Microtubule organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear bodies" "HPA049775: AB_2680874, HPA054782: AB_2682599" "unprognostic (2.90e-1)" "unprognostic (2.62e-2)" "unprognostic (2.25e-1)" "unprognostic (2.75e-3)" "unprognostic (6.56e-3)" "unprognostic (2.90e-3)" "unprognostic (2.30e-1)" "unprognostic (4.74e-2)" "unprognostic (6.01e-3)" "unprognostic (3.92e-2)" "unprognostic (3.81e-2)" "unprognostic (2.33e-1)" "unprognostic (2.09e-2)" "unprognostic (6.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.39e-3)" "unprognostic (1.89e-2)" 1.1 1.2 1.3 1.4 1.8 0.7 1.3 1.5 1.5 1.1 1.2 1.1 1.8 0.8 1.1 1.1 0.7 0.8 0.7 1.3 1.2 1.4 2.0 1.0 1.7 1.5 1.4 1.7 0.8 1.3 0.5 1.2 1.7 0.8 1.2 3.0 1.3 0.7 3.1 2.5 1.5 0.6 1.2 1.8 1.3 1.0 1.7 1.2 1.1 1.8 1.8 0.7 0.9 2.7 2.1 0.7 1.3 0.9 1.6 1.8 0.9 1.5 1.8 1.4 1.6 1.0 0.9 2.6 1.0 0.7 1.9 1.1 1.2 1.2 2.7 3.5 1.3 1.3 0.7 0.5 0.7 0.6 1.5 0.8 2.1 2.0 1.7 0.7 0.6 4.3 0.6 4.9 1.1 0.4 1.5 1.9 0.7 1.4 1.0 1.3 2.3 1.7 1.1 0.6 1.3 0.9 0.7 0.3 1.7 1.1 0.4 0.6 0.6 1.6 1.5 2.0 1.6 3.9 2.5 1.1 1.0 1.1 1.2 2.6 0.7 0.9 1.0 0.7 1.0 0.9 1.7 1.0 0.4 1.0 1.2 1.2 1.4 1.0 1.3 0.9 2.1 0.6 1.3 1.8 1.5 1.5 1.3 1.2 1.5 1.4 1.7 1.2 1.7 2.7 9.1 32.1 52.0 1.3 6.4 7.1 5.0 3.1 9.1 3.9 7.7 10.4 11.7 7.2 16.3 5.5 2.1 4.2 4.5 7.1 11.7 3.2 1.7 4.0 3.1 8.2 3.0 4.0 0.8 3.3 3.5 6.8 3.1 4.1 12.6 2.1 5.3 7.1 4.1 3.3 0.8 6.2 0.0 5.1 6.6 1.0 4.1 8.7 1.8 0.0 2.5 2.2 2.1 1.5 1.7 3.1 2.7 1.5 5.8 3.4 7.4 9.2 12.9 5.7 0.0 5.5 3.9 18.0 11.1 6.7 8.0 1.6 8.1 2.8 3.5 3.9 FBXO6 "FBG2, FBS2, FBX6, Fbx6b" ENSG00000116663 "F-box protein 6" Q9NRD1 1 11664200-11674354 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.6;Late spermatids: 117.8;NK-cells: 60.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051175 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA051175: AB_2681372" "unprognostic (3.23e-3)" "unprognostic (2.58e-2)" "unprognostic (8.27e-2)" "unprognostic (2.69e-3)" "unprognostic (1.11e-1)" "unprognostic (6.64e-2)" "unprognostic (9.46e-3)" "unprognostic (1.22e-1)" "unprognostic (1.18e-1)" "prognostic favorable (7.12e-4)" "unprognostic (1.47e-2)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.83e-6)" "unprognostic (2.65e-2)" "unprognostic (2.11e-1)" "unprognostic (5.23e-2)" "prognostic favorable (5.90e-4)" 6.5 10.7 9.9 11.8 10.1 20.3 6.7 10.3 12.4 7.6 8.2 7.6 13.5 5.0 6.0 10.3 14.1 8.7 10.0 9.8 11.5 7.8 18.5 11.4 18.3 9.9 10.5 5.9 13.8 13.5 6.1 2.6 9.7 8.7 6.8 3.6 13.0 8.4 18.7 9.5 8.2 7.4 10.0 13.0 9.8 10.8 12.6 7.1 6.7 14.5 11.1 9.5 7.0 9.8 10.0 7.3 0.8 0.4 2.1 6.8 4.5 4.2 6.6 20.1 9.2 7.6 8.3 0.3 18.7 7.0 5.5 0.2 6.8 7.5 1.5 26.3 1.0 0.2 1.0 7.7 15.4 9.4 0.1 7.9 15.8 2.5 6.3 4.3 2.6 10.3 22.7 18.7 1.8 19.1 3.4 7.8 0.8 10.2 9.7 2.3 0.1 0.7 6.9 1.4 1.6 2.0 9.3 10.9 14.3 1.8 10.5 10.2 2.0 1.0 0.8 2.7 0.3 10.0 7.5 3.9 1.2 21.6 1.8 17.1 49.5 65.0 47.0 75.0 25.4 15.3 12.0 31.3 66.5 15.0 7.1 23.7 41.4 41.4 91.0 27.3 13.1 36.6 9.9 10.1 10.3 12.4 9.8 11.5 9.9 10.5 9.7 10.0 12.6 9.8 6.0 6.4 6.9 3.3 8.4 7.0 6.6 14.6 4.0 4.3 8.3 7.4 6.8 2.8 15.0 9.2 2.1 1.1 19.5 10.7 0.0 14.5 60.6 15.7 4.5 4.0 4.9 1.7 1.8 38.5 9.2 7.8 8.6 5.3 3.8 2.2 8.2 19.9 26.2 5.0 2.6 8.3 8.2 15.4 34.7 117.8 8.1 18.3 7.2 1.0 37.8 9.0 60.8 0.0 1.3 13.0 10.8 11.3 12.2 11.3 14.3 15.6 36.5 7.8 0.0 3.3 4.0 4.0 11.9 7.3 9.8 1.8 16.0 1.8 9.2 11.2 FCGBP FC(GAMMA)BP ENSG00000275395 "Fc fragment of IgG binding protein" 19 39863323-39934626 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.9;salivary gland: 85.4;stomach 1: 85.5;thyroid gland: 99.9" "Cell type enriched" "Detected in many" 9 "Intestinal goblet cells: 6081.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;Daudi: 1.8;JURKAT: 1.7;MOLT-4: 1.8;RH-30: 7.1" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" 5.9 10.0 5.1 14.0 7.2 0.4 3.2 4.0 8.4 56.4 15.0 206.9 68.7 1.2 0.6 4.6 9.8 49.2 2.9 5.6 6.8 11.3 1.0 1.9 0.9 20.1 10.6 3.7 4.9 0.5 3.4 2.9 11.1 3.8 67.7 0.6 85.4 1.4 0.4 14.8 148.7 2.6 5.9 1.5 85.5 2.9 14.0 1.5 99.9 0.0 0.7 3.4 1.6 12.0 0.0 4.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.1 1.8 0.6 0.1 1.5 0.3 0.1 7.1 1.6 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.0 0.1 5.1 7.2 4.0 8.4 5.6 6.8 20.1 10.6 11.1 5.9 14.0 12.0 0.6 3.2 5.1 2.6 4.6 3.7 1.9 15.8 1.2 1.1 1.3 3.4 2.8 70.1 60.0 25.8 0.0 0.7 1.8 622.2 0.0 5.2 7.2 4.2 0.3 26.7 81.1 0.0 0.6 0.9 0.4 1.9 552.0 4.0 15.9 0.4 0.7 1.3 44.0 0.0 0.4 6081.9 2.0 30.2 12.6 9.2 0.9 21.6 8.8 15.9 0.9 0.4 1.0 0.5 0.2 3.9 253.6 0.0 2.1 13.8 413.5 1.2 11.0 2.0 59.2 0.5 1.1 0.5 2.4 0.4 6.8 0.4 5.6 0.9 191.4 164.1 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCRLA "FCRL, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRLM1, FCRLX, FREB, MGC4595" ENSG00000132185 "Fc receptor like A" Q7L513 1 161706972-161714352 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 98.4" "Group enriched" "Detected in some" 6 "B-cells: 124.2;Melanocytes: 67.6" "Cancer enriched" "Detected in many" 21 "melanoma: 38.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 9 "memory B-cell: 368.0;naive B-cell: 341.5" "Lineage enriched" "Detected in many" 10 "B-cells: 368.0" "Group enriched" "Detected in some" 6 "Daudi: 484.1;SK-MEL-30: 197.8;U-698: 260.5" "Not detected" "Not detected" "Not detected" "Not detected" CAB016545 Enhanced "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB016545: AB_2247037" "unprognostic (5.46e-4)" "unprognostic (7.19e-2)" "unprognostic (3.69e-3)" "unprognostic (4.75e-4)" "unprognostic (4.69e-2)" "unprognostic (1.48e-4)" "unprognostic (1.45e-2)" "unprognostic (4.15e-3)" "unprognostic (8.66e-2)" "unprognostic (3.58e-4)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (6.84e-5)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.56e-1)" "unprognostic (2.08e-2)" 0.8 0.2 0.5 23.5 0.3 4.1 0.5 1.1 0.7 0.3 0.3 2.6 0.9 0.4 0.6 0.5 0.1 1.1 0.6 0.4 0.2 0.3 0.4 0.6 68.5 0.3 0.3 0.2 0.0 0.0 0.0 0.3 0.3 0.8 2.8 0.3 2.3 0.1 0.3 1.2 19.1 0.4 0.1 38.5 4.1 0.2 0.5 7.7 0.5 0.3 98.4 3.4 0.1 0.4 0.7 0.0 0.0 0.0 0.4 0.4 0.0 2.7 7.4 0.2 0.5 0.0 0.0 484.1 0.2 7.0 0.0 0.1 0.0 0.7 0.8 1.8 0.0 0.5 0.0 0.0 0.0 0.2 2.0 0.4 0.5 2.4 0.4 0.1 0.0 0.0 0.9 26.7 0.1 0.0 0.1 0.3 0.1 0.0 0.1 4.0 8.3 52.4 0.0 0.1 0.0 0.0 0.3 0.1 197.8 0.0 0.0 0.2 0.5 0.6 0.7 0.5 0.5 0.7 0.3 260.5 2.9 0.3 44.3 0.4 0.3 0.2 0.8 0.0 0.1 368.0 0.2 0.4 0.4 341.5 0.2 0.1 0.6 0.2 0.2 38.4 0.2 17.0 0.5 0.3 1.1 0.7 0.4 0.2 0.3 0.3 0.3 0.1 0.5 0.4 0.0 0.0 0.6 0.0 124.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.7 67.6 0.0 0.4 0.0 1.0 0.5 0.1 0.3 0.1 0.0 14.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.4 0.0 1.6 0.0 0.1 0.0 FDXR "ADR, ADXR" ENSG00000161513 "Ferredoxin reductase" P22570 17 74862497-74873031 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "adrenal gland: 343.1" "Group enriched" "Detected in many" 7 "Granulosa cells: 329.3;Theca cells: 794.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 89.5;Hep G2: 173.5" "Low region specificity" "Detected in all" "CAB008597, CAB009818, HPA044393, HPA053673" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 52: Non-specific - Transcription" Mitochondria "CAB008597: AB_1615557, CAB009818: AB_2102601, HPA044393: AB_2678927, HPA053673: AB_2682225" "unprognostic (2.69e-2)" "unprognostic (1.17e-3)" "unprognostic (7.51e-2)" "prognostic favorable (2.38e-4)" "unprognostic (3.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" "unprognostic (1.68e-2)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (6.30e-2)" "unprognostic (1.42e-2)" "unprognostic (1.19e-2)" "unprognostic (4.50e-2)" "unprognostic (4.03e-2)" "unprognostic (2.13e-1)" 3.9 343.1 6.9 2.4 8.4 2.2 3.8 7.8 8.1 7.8 8.6 9.7 4.6 6.7 5.1 26.0 12.9 4.1 6.0 6.6 6.7 6.5 14.9 5.3 2.9 7.6 7.9 20.5 12.9 5.9 4.1 3.0 7.5 6.7 3.2 0.5 7.1 4.4 7.7 16.4 5.6 2.3 7.4 33.9 7.6 45.6 7.0 4.7 6.0 1.7 2.5 6.2 10.5 7.5 12.5 65.6 9.6 10.8 6.8 9.1 89.5 14.8 15.9 8.6 17.1 18.3 10.8 29.6 2.6 6.2 4.8 24.9 6.9 18.4 2.5 27.9 15.2 22.6 10.6 173.5 19.0 5.0 75.1 29.2 20.3 9.1 3.1 7.0 43.9 10.9 36.1 4.8 13.4 53.4 19.7 10.6 5.5 11.8 14.5 10.6 16.4 16.2 7.1 21.0 5.2 12.1 10.0 21.7 11.2 10.9 47.4 4.7 20.5 5.9 51.9 9.4 7.4 12.7 2.3 6.5 16.1 7.7 20.6 1.7 6.0 5.0 5.6 4.5 5.0 4.8 5.1 6.8 7.3 2.4 4.4 5.4 2.0 10.3 3.4 1.4 15.4 5.2 6.9 8.4 7.8 8.1 6.6 6.7 7.6 7.9 7.5 7.4 7.0 7.5 4.0 3.2 3.9 7.5 8.2 9.7 17.8 42.6 17.1 4.9 6.6 8.4 3.8 5.7 23.3 9.2 4.2 53.2 2.8 18.6 5.9 11.1 6.5 28.2 4.3 4.6 7.1 4.0 1.4 7.9 18.9 12.9 13.7 3.5 5.7 329.3 12.5 13.9 23.1 3.3 2.2 13.1 36.7 6.2 2.7 14.9 5.9 4.6 5.4 1.0 3.9 11.4 8.2 3.0 1.3 9.0 16.9 4.5 7.1 5.2 24.9 21.7 73.6 5.1 0.0 6.2 18.3 6.3 6.1 33.7 18.2 46.1 8.6 794.1 20.3 17.4 FERMT1 "C20orf42, FLJ20116, KIND1, UNC112A, URP1" ENSG00000101311 "Fermitin family member 1" Q9BQL6 20 6074845-6123030 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 121.3;Oligodendrocyte precursor cells: 229.7;Pancreatic endocrine cells: 384.1;Undifferentiated cells: 95.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 84.3;HaCaT: 95.4;HBEC3-KT: 100.2;OE19: 75.1;RT4: 54.4" "Region enriched" "Detected in single" 5 "hippocampal formation: 2.0" "Not detected" "Not detected" "HPA039778, HPA041966" Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA039778: AB_10805593, HPA041966: AB_10795387" "unprognostic (1.08e-3)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "unprognostic (3.64e-3)" "unprognostic (1.75e-3)" "unprognostic (2.82e-1)" "unprognostic (9.49e-2)" "unprognostic (1.53e-3)" "unprognostic (2.13e-1)" "unprognostic (1.83e-1)" "prognostic unfavorable (6.60e-4)" "unprognostic (4.38e-2)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (2.04e-1)" "unprognostic (4.60e-2)" "unprognostic (5.33e-2)" 0.6 11.4 1.4 9.3 2.2 0.3 1.5 1.5 1.4 2.1 0.0 24.6 14.8 2.3 0.8 12.8 3.5 2.6 1.0 1.6 2.0 4.0 0.3 1.0 0.0 3.1 2.8 4.2 2.7 12.5 0.2 4.8 3.2 5.0 35.8 0.0 1.9 4.3 0.1 17.6 11.0 2.0 2.6 0.4 13.0 0.5 2.2 2.4 2.9 0.3 5.1 6.8 3.4 3.4 53.4 14.4 0.0 0.0 0.4 5.0 18.5 2.8 0.1 1.9 0.8 24.8 84.3 0.0 14.1 2.9 6.3 95.4 36.8 100.2 2.0 0.0 2.6 8.2 10.7 26.8 1.2 0.0 2.5 4.8 43.6 11.5 24.0 0.4 1.2 0.3 0.0 0.2 2.4 1.4 0.0 2.4 11.5 75.1 41.1 0.0 12.5 29.9 9.9 54.4 7.7 0.9 8.8 0.3 0.0 0.7 8.4 2.2 0.4 5.1 3.4 0.7 39.5 0.2 0.1 0.1 3.7 9.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 1.5 1.4 1.6 2.0 3.1 2.8 3.2 2.6 2.2 3.4 0.1 0.0 0.6 0.3 0.0 41.4 51.5 44.8 121.3 0.0 3.4 16.3 1.3 8.6 16.0 0.0 0.0 65.0 0.1 61.2 1.9 34.5 0.1 4.0 31.8 0.6 15.6 8.4 2.3 40.3 31.3 7.5 46.9 2.0 0.0 13.5 0.4 0.4 4.9 0.0 2.2 49.0 2.0 0.0 0.8 1.1 10.8 1.5 1.8 7.5 0.1 0.0 0.0 229.7 0.5 384.1 23.5 3.0 1.4 20.1 13.9 15.8 5.7 0.0 0.0 6.2 2.9 0.2 0.6 80.6 43.0 7.3 1.0 6.2 95.2 44.8 FEZ2 ENSG00000171055 "Fasciculation and elongation protein zeta 2" Q9UHY8 2 36531805-36646087 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035978 Uncertain Approved "Nucleoli,Nucleoli rim,Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" "Golgi apparatus, Cytosol" "HPA035978: AB_10672235" "unprognostic (1.42e-1)" "unprognostic (5.02e-3)" "unprognostic (2.89e-1)" "unprognostic (1.15e-2)" "unprognostic (2.91e-2)" "unprognostic (1.94e-3)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.09e-1)" "unprognostic (7.05e-2)" "unprognostic (2.42e-1)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (6.65e-2)" "unprognostic (7.82e-3)" "unprognostic (7.07e-2)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" 53.0 39.1 48.2 21.0 51.6 16.5 35.9 48.2 68.6 26.9 42.8 34.5 22.1 33.1 18.9 31.7 23.8 23.6 46.7 49.2 48.4 33.6 29.4 27.1 24.3 49.5 46.3 27.6 10.8 20.3 14.2 46.8 48.2 23.5 27.9 26.5 17.1 32.5 108.1 17.0 28.5 41.1 50.1 30.3 21.9 20.8 49.6 18.2 23.9 78.5 19.5 29.1 24.3 56.3 64.9 37.1 49.4 22.3 91.3 122.1 39.5 157.1 76.5 90.7 56.0 24.6 21.5 39.1 94.7 199.2 41.0 25.1 42.4 54.3 98.5 9.3 24.7 31.7 12.2 43.5 44.4 32.9 8.5 119.9 44.2 57.8 69.6 61.2 131.0 9.5 35.4 12.0 170.2 22.7 19.6 27.5 27.1 33.9 57.8 16.9 44.3 14.0 72.9 57.6 1.9 45.7 38.7 31.9 37.8 51.7 11.3 39.1 161.2 59.7 32.9 33.4 92.9 9.8 11.5 26.6 58.9 22.4 84.8 2.5 3.5 5.1 1.7 3.4 1.0 1.6 1.3 1.0 3.5 1.0 1.5 0.7 4.2 3.2 2.3 15.6 1.4 0.8 48.2 51.6 48.2 68.6 49.2 48.4 49.5 46.3 48.2 50.1 49.6 56.3 109.4 54.5 37.5 25.8 23.7 31.4 94.7 45.5 41.5 52.5 31.7 33.1 43.1 17.2 70.2 58.8 45.9 96.4 61.1 57.6 56.7 80.3 5.6 38.4 44.7 100.9 24.0 15.3 45.4 30.6 87.6 50.7 27.0 64.3 24.1 66.0 97.5 37.2 93.7 21.9 22.9 28.8 38.7 88.1 65.4 10.7 54.3 64.6 56.9 45.0 56.0 97.1 35.0 23.1 50.5 74.4 41.4 66.2 17.9 99.1 65.6 45.1 35.9 36.3 59.2 64.0 51.2 12.1 34.9 24.0 32.1 180.1 24.2 47.2 37.7 140.6 FGF1 "AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1" ENSG00000113578 "Fibroblast growth factor 1" P05230 5 142592178-142698070 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 295.2;choroid plexus: 125.8" "Cell type enhanced" "Detected in many" "Astrocytes: 75.1;Cardiomyocytes: 62.4;Muller glia cells: 69.4;Oligodendrocytes: 119.8" "Cancer enriched" "Detected in many" 12 "glioma: 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.6;BJ hTERT+: 33.0;BJ hTERT+ SV40 Large T+: 35.9;BJ hTERT+ SV40 Large T+ RasG12V: 45.0;HBF TERT88: 64.3;hTEC/SVTERT24-B: 45.4;LHCN-M2: 30.6;U-2 OS: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003265, CAB017519" Enhanced Supported Nucleoplasm "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB017519: AB_629473, HPA003265: AB_1848522" "unprognostic (1.25e-2)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (2.55e-2)" "unprognostic (3.52e-1)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.63e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.54e-1)" "prognostic favorable (2.59e-5)" "unprognostic (3.72e-4)" "unprognostic (2.49e-1)" "prognostic favorable (3.45e-5)" "unprognostic (3.01e-4)" 17.9 3.3 206.3 1.6 259.3 1.1 12.5 213.9 295.2 1.3 125.8 2.4 1.0 3.1 7.9 2.0 1.7 2.5 50.2 183.5 245.5 66.5 1.7 2.8 1.2 236.2 237.7 0.9 0.8 4.3 6.5 2.1 259.9 1.8 1.3 18.8 7.3 2.3 2.2 1.7 1.2 2.5 225.4 6.9 0.8 2.0 244.3 1.5 5.6 7.8 2.0 1.2 1.0 272.8 5.6 0.3 0.3 1.5 1.1 3.3 1.8 44.6 33.0 35.9 45.0 0.2 0.2 1.3 3.1 15.4 2.1 0.7 0.0 3.5 64.3 0.2 0.0 0.0 0.8 0.4 0.6 0.0 0.4 1.6 1.1 45.4 2.7 9.7 0.0 0.2 0.0 1.6 30.6 0.7 0.1 0.9 1.4 0.1 1.4 0.2 1.5 0.6 1.5 0.2 1.1 2.3 0.1 0.9 0.6 8.0 0.0 0.2 1.1 5.8 33.0 0.8 21.3 0.8 0.4 0.3 8.2 0.3 1.6 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.3 0.3 0.0 0.1 0.2 0.1 0.0 206.3 259.3 213.9 295.2 183.5 245.5 236.2 237.7 259.9 225.4 244.3 272.8 1.4 0.0 0.0 75.1 0.1 0.4 5.0 5.7 7.4 3.5 1.2 25.4 62.4 0.0 2.1 20.2 16.7 1.1 0.1 0.0 0.0 1.1 0.4 0.0 0.7 4.8 0.0 0.0 13.0 0.0 0.5 4.7 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 14.6 0.0 12.2 0.0 0.0 1.4 0.0 0.2 3.6 29.0 0.0 69.4 0.0 15.1 119.8 0.6 0.0 0.4 0.0 5.3 0.0 0.3 0.1 11.6 6.6 0.5 23.4 0.1 0.1 0.6 0.0 0.8 0.4 0.0 0.0 0.7 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 216.6;Leydig cells: 83.3;Proximal tubular cells: 53.4;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 112.1;ASC TERT1: 66.1;BJ: 45.6;fHDF/TERT166: 50.3;HSkMC: 84.8;RH-30: 119.7;U-138 MG: 56.5" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" 43.8 4.5 3.4 31.5 3.9 0.1 8.5 4.2 5.2 29.4 2.1 11.1 3.7 29.2 4.3 9.5 15.4 46.0 10.5 3.3 4.8 4.5 1.4 12.9 8.3 4.6 4.6 13.4 2.2 3.6 2.2 23.5 5.1 16.2 9.6 8.4 5.1 12.0 2.2 2.6 3.6 26.9 4.1 1.8 5.5 2.3 4.5 3.0 7.4 23.8 4.8 63.3 10.3 4.5 0.2 0.0 0.2 0.3 112.1 66.1 0.1 45.6 25.7 0.0 0.1 0.0 0.3 0.2 0.2 50.3 0.4 0.9 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 10.6 0.3 0.1 84.8 0.8 9.4 0.0 0.3 0.0 0.0 0.1 0.3 5.4 0.1 0.0 0.1 0.2 0.1 0.3 0.1 119.7 0.1 0.1 0.1 1.8 0.6 0.4 0.0 0.4 0.2 0.2 0.2 0.2 56.5 0.5 1.1 0.2 0.5 0.4 0.0 13.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.9 4.2 5.2 3.3 4.8 4.6 4.6 5.1 4.1 4.5 4.5 16.1 12.8 19.3 2.0 2.2 14.4 16.8 1.3 1.2 7.9 11.1 9.5 46.8 7.2 0.5 9.2 2.1 6.2 3.2 0.2 119.3 2.0 3.3 8.8 46.2 5.2 0.0 2.7 1.9 0.6 3.3 216.6 2.0 29.2 1.3 0.6 1.8 2.7 2.0 3.3 3.3 0.0 2.0 1.6 15.9 4.0 83.3 1.9 7.2 1.0 0.2 9.8 2.1 1.5 2.9 0.6 0.0 4.9 0.7 9.4 0.0 53.4 0.3 6.1 6.6 43.6 71.6 0.6 0.7 1.8 12.6 2.9 2.9 2.9 0.1 8.4 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 207.8;lung: 86.5;lymphoid tissue: 141.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 182.2;Langerhans cells: 63.8;Macrophages: 155.9;monocytes: 159.7;NK-cells: 259.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Daudi: 86.0;U-266/70: 153.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" 25.0 6.8 12.8 62.2 11.9 207.8 16.0 11.9 19.1 7.6 11.5 6.0 3.9 8.1 1.7 5.2 15.6 12.7 8.7 11.4 12.3 7.5 10.8 86.5 27.5 13.6 12.7 2.9 5.8 1.6 2.7 7.9 14.5 7.2 4.0 0.7 6.6 2.4 3.2 4.5 10.1 16.3 12.5 141.1 5.9 2.5 17.2 8.4 7.4 6.5 20.0 17.8 7.3 12.6 0.0 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 86.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 1.7 29.3 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 3.8 5.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 153.1 2.1 6.5 0.0 19.5 0.0 30.8 381.4 229.4 189.5 469.1 11.3 54.0 15.8 89.1 196.1 84.0 8.0 78.4 272.9 264.5 405.2 9.0 1.2 494.1 12.8 11.9 11.9 19.1 11.4 12.3 13.6 12.7 14.5 12.5 17.2 12.6 8.6 6.4 20.0 0.0 24.9 2.8 0.6 0.2 0.0 0.0 0.4 0.6 1.6 1.5 5.7 1.8 0.0 0.5 55.2 0.0 0.0 0.0 0.3 0.1 0.2 14.9 0.0 7.4 0.2 0.2 0.7 2.7 1.5 0.1 13.3 0.1 6.8 1.9 56.8 0.0 0.1 0.0 0.0 182.2 63.8 0.7 0.3 155.9 1.8 6.5 159.7 0.1 259.5 1.0 0.4 0.0 1.2 0.0 4.2 0.4 0.0 0.7 1.5 0.0 0.0 0.7 0.6 0.2 0.5 0.5 1.1 1.0 28.0 0.0 0.0 2.5 FHL5 "ACT, dJ393D12.2, FLJ33049" ENSG00000112214 "Four and a half LIM domains 5" Q5TD97 6 96562548-96616636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.5" "Group enriched" "Detected in some" 20 "Early spermatids: 1160.3;Late spermatids: 1540.1" "Cancer enhanced" "Detected in many" "renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "ASC diff: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "prognostic favorable (4.81e-4)" "unprognostic (4.93e-2)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.84e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.22e-1)" "unprognostic (3.48e-3)" 35.7 10.3 5.4 4.4 8.5 0.0 16.0 5.8 7.5 27.8 6.2 5.8 2.5 15.0 17.6 9.6 21.5 12.9 5.6 4.9 5.3 6.4 0.4 14.0 1.8 6.3 5.8 11.4 4.6 3.3 1.2 0.6 7.1 4.9 5.0 0.4 2.1 11.1 8.9 5.5 5.1 9.6 5.4 3.5 4.0 65.5 7.2 1.2 8.9 14.6 0.8 6.8 10.3 5.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 8.5 5.8 7.5 4.9 5.3 6.3 5.8 7.1 5.4 7.2 5.5 5.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1160.3 0.0 0.1 3.8 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1540.1 52.5 1.1 5.4 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.2 0.0 0.0 0.0 0.0 52.6 1.9 67.4 13.2 4.4 0.0 0.3 0.0 0.6 0.1 0.0 0.2 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FLOT1 ENSG00000137312 "Flotillin 1" O75955 6 30727709-30742732 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 314.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 423.3;hTERT-RPE1: 242.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001393, CAB007766" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Vesicles, Plasma membrane" "CAB007766: AB_562116, HPA001393: AB_1078892" "unprognostic (2.68e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (3.41e-3)" "unprognostic (2.68e-3)" "unprognostic (1.86e-1)" "unprognostic (2.65e-1)" "prognostic favorable (3.06e-4)" "unprognostic (1.81e-2)" "unprognostic (9.36e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (6.43e-3)" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (2.46e-2)" 141.7 239.5 49.3 27.9 54.6 41.7 129.8 49.4 60.9 111.1 56.8 150.3 28.7 108.9 8.4 81.8 95.8 23.1 234.5 55.1 57.9 146.1 127.3 136.8 22.1 50.9 51.5 84.1 88.5 41.4 102.5 35.0 57.4 109.6 17.7 6.3 99.1 45.8 190.0 51.7 87.1 33.0 45.8 129.6 96.9 65.0 53.6 24.9 111.7 83.1 17.0 134.5 96.9 48.8 54.3 18.3 46.4 62.0 49.1 71.0 1.3 59.7 67.5 82.8 79.3 19.4 30.0 13.0 29.0 101.3 423.3 41.8 35.0 20.1 28.6 36.1 1.3 41.1 17.5 19.1 119.2 12.2 67.0 75.4 30.6 40.9 71.3 242.7 65.9 37.9 21.7 52.7 77.9 22.9 38.0 14.5 15.1 29.4 15.7 20.2 48.4 38.0 30.3 13.0 16.4 17.2 33.7 28.7 164.6 30.4 43.8 10.1 44.0 199.5 37.6 20.6 120.6 18.6 19.7 28.8 26.2 42.6 122.7 179.3 76.9 132.0 35.0 38.9 24.1 28.0 21.3 30.4 58.9 23.0 23.7 27.4 314.3 79.9 26.3 59.2 3.9 58.3 49.3 54.6 49.4 60.9 55.1 57.9 50.9 51.5 57.4 45.8 53.6 48.8 175.4 89.8 77.0 26.1 38.1 28.7 111.5 44.9 80.2 14.7 72.1 73.4 90.6 62.9 59.2 84.6 6.2 82.2 57.7 103.2 123.3 77.6 60.2 73.9 50.1 141.6 68.8 41.7 41.3 85.9 70.7 67.6 55.5 75.2 143.3 41.4 154.9 59.7 130.6 20.2 40.2 66.6 57.0 61.3 84.9 144.1 61.8 89.4 71.2 28.1 99.2 64.7 68.0 27.2 22.7 65.7 112.0 38.0 60.4 69.5 89.0 172.1 80.7 18.1 52.6 58.1 65.9 80.2 26.7 63.7 26.9 61.6 51.2 29.1 83.2 99.4 FMNL2 "FHOD2, KIAA1902" ENSG00000157827 "Formin like 2" Q96PY5 2 152335174-152649826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 223.5" "Cell type enhanced" "Detected in many" "Astrocytes: 668.0;Excitatory neurons: 574.9;Inhibitory neurons: 321.9;Oligodendrocyte precursor cells: 371.0;Oligodendrocytes: 2442.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 5 "monocytes: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 191.4;hTERT-HME1: 123.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005464 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Golgi apparatus, Plasma membrane" "HPA005464: AB_1848965" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (8.75e-3)" "unprognostic (3.06e-2)" "unprognostic (7.40e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (2.54e-1)" "unprognostic (4.66e-2)" "unprognostic (5.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.58e-1)" "unprognostic (3.73e-2)" "unprognostic (1.58e-1)" 26.4 25.2 88.9 11.1 152.3 0.7 20.8 135.2 119.3 18.1 73.6 15.2 8.9 20.7 14.9 8.5 15.3 16.8 12.0 92.9 102.6 22.2 8.1 32.2 14.2 172.3 136.3 54.0 18.1 23.1 28.4 58.2 165.5 15.2 12.3 10.6 32.1 11.7 24.1 11.3 11.6 16.3 121.6 19.8 17.3 9.0 128.5 14.8 33.1 19.3 8.4 19.3 18.3 223.5 14.5 15.1 45.9 25.5 54.5 58.3 191.4 14.4 29.4 24.9 34.8 16.3 0.9 0.3 29.8 12.6 53.7 16.2 22.4 45.8 39.6 0.1 23.4 0.2 10.0 70.2 15.7 4.0 0.8 38.4 27.8 48.2 123.5 48.3 44.7 6.6 0.6 0.3 13.9 4.0 0.8 4.5 29.5 12.4 30.0 25.9 9.9 20.9 72.9 9.9 46.6 38.0 12.2 4.5 51.4 38.7 1.1 1.5 49.9 37.4 1.0 12.7 25.0 1.3 0.5 0.1 34.7 3.3 77.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 88.9 152.3 135.2 119.3 92.9 102.6 172.3 136.3 165.5 121.6 128.5 223.5 21.5 25.6 25.9 668.0 2.7 26.4 23.0 14.0 19.4 23.8 11.4 10.0 3.8 1.5 16.4 11.0 0.0 36.1 4.5 2.6 13.7 20.4 24.5 14.1 10.8 29.1 8.3 0.4 574.9 6.9 17.8 36.2 8.2 27.0 1.3 36.0 20.0 1.3 40.6 0.0 321.9 3.3 10.2 64.8 53.0 10.5 35.1 31.5 7.2 245.4 4.4 3.9 1.0 371.0 2442.0 10.0 2.1 41.3 5.6 33.5 0.7 8.9 8.5 2.0 6.6 18.7 13.2 6.7 8.0 6.3 16.9 27.0 2.1 13.0 6.1 13.2 FNDC3B "DKFZp762K137, FAD104, FLJ23399, PRO4979, YVTM2421" ENSG00000075420 "Fibronectin type III domain containing 3B" Q53EP0 3 172039578-172401669 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 283.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "cerebral cortex: 29.4;hypothalamus: 8.2;pons: 9.4;thalamus: 14.4" "Immune cell enhanced" "Detected in many" "neutrophil: 37.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 37.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007859 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA007859: AB_1078900" "unprognostic (7.18e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (6.03e-2)" "unprognostic (6.38e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (3.25e-2)" "prognostic unfavorable (9.85e-4)" "unprognostic (2.17e-3)" "unprognostic (1.98e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (9.06e-5)" "unprognostic (3.50e-2)" "prognostic unfavorable (5.65e-7)" "unprognostic (4.35e-2)" "unprognostic (1.19e-1)" "unprognostic (3.51e-2)" "unprognostic (3.00e-2)" 34.4 25.5 1.1 26.3 1.1 37.0 16.6 0.6 29.4 26.0 11.9 19.8 13.0 21.9 18.2 9.2 12.5 19.4 24.4 3.5 8.2 17.5 28.5 21.8 8.9 3.3 3.4 22.8 28.3 15.0 8.5 52.7 9.4 12.9 19.6 4.4 21.3 15.6 21.2 7.0 11.4 25.4 0.7 14.7 20.6 9.3 14.4 6.8 32.4 18.5 11.0 38.6 9.5 1.9 47.4 55.9 36.0 43.5 107.6 73.6 87.6 68.3 73.1 43.3 58.3 30.5 100.5 4.2 178.9 99.0 85.6 27.4 12.4 53.2 74.9 27.5 9.2 6.0 34.8 78.6 109.2 62.1 100.1 75.5 24.9 80.8 75.9 102.8 116.7 8.1 10.9 32.6 44.3 14.8 2.4 24.9 20.8 18.0 22.0 5.4 37.5 21.9 44.8 42.1 2.2 10.8 62.2 30.6 53.9 49.3 31.1 28.5 182.6 60.5 28.5 78.9 52.2 67.3 84.0 9.3 63.5 32.7 61.0 13.5 8.3 20.4 4.2 5.3 1.8 1.1 1.3 2.3 4.7 0.1 1.4 2.5 37.5 4.6 2.7 0.7 1.2 3.4 1.1 1.1 0.6 29.4 3.5 8.2 3.3 3.4 9.4 0.7 14.4 1.9 54.8 86.6 49.0 115.2 19.2 63.9 51.4 61.1 39.3 7.5 27.4 31.9 51.0 41.5 47.9 46.0 12.5 41.4 29.2 53.1 15.6 69.8 16.2 73.7 73.4 61.5 16.8 16.4 37.9 45.6 99.6 103.7 32.6 179.5 15.2 95.2 58.2 68.9 47.1 0.0 43.9 30.7 12.2 59.2 53.3 9.3 57.5 65.1 69.4 155.5 52.2 17.4 39.1 115.6 31.4 78.5 44.8 54.5 283.6 67.8 16.1 35.7 33.6 11.5 52.6 89.4 69.1 2.3 3.2 18.6 33.5 34.8 23.1 26.0 26.2 88.4 FOXF2 "FKHL6, FREAC2" ENSG00000137273 "Forkhead box F2" Q12947 6 1389576-1395603 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.2" "Cell type enhanced" "Detected in some" "Endothelial cells: 5.2;Fibroblasts: 7.9;Microglial cells: 19.7;Smooth muscle cells: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 70.4;HEK 293: 24.3;U-2197: 28.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.14e-2)" "unprognostic (2.03e-1)" "unprognostic (8.33e-2)" "unprognostic (1.68e-1)" "unprognostic (5.39e-2)" "unprognostic (3.32e-2)" "unprognostic (8.12e-2)" "unprognostic (1.11e-1)" "unprognostic (9.89e-3)" "unprognostic (2.53e-1)" "unprognostic (4.50e-2)" "unprognostic (8.76e-2)" "unprognostic (8.75e-7)" "unprognostic (1.03e-1)" "unprognostic (4.74e-2)" "unprognostic (2.08e-2)" "unprognostic (8.29e-2)" 1.8 0.4 8.1 1.8 6.0 0.0 2.4 5.5 10.3 1.0 5.1 40.2 6.0 0.2 0.8 9.6 0.5 1.5 0.7 6.1 5.2 0.2 0.1 17.8 0.4 10.1 6.0 0.1 1.0 0.6 7.6 9.1 10.0 10.8 9.3 0.1 1.3 0.6 1.0 1.4 18.7 3.5 5.1 0.0 17.8 0.9 7.1 0.0 3.7 3.5 1.8 11.1 2.1 6.9 1.6 3.4 1.0 0.8 3.2 4.9 0.1 15.6 70.4 6.3 2.9 0.3 0.0 0.0 3.3 4.6 6.8 11.9 12.2 0.6 2.8 0.0 24.3 0.0 5.7 0.0 6.1 0.0 0.4 0.8 5.0 0.0 5.9 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.1 0.1 0.0 0.0 0.0 6.9 0.2 0.0 3.7 0.0 5.2 1.3 0.0 0.2 0.0 5.8 11.0 28.7 2.8 0.3 0.0 0.0 0.0 4.7 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 6.0 5.5 10.3 6.1 5.2 10.1 6.0 10.0 5.1 7.1 6.9 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.0 5.2 0.0 0.0 1.1 0.0 1.5 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.4 2.5 0.1 1.8 19.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 5.5 0.2 1.5 0.3 0.1 0.1 0.1 0.0 0.0 0.0 FOXJ1 "FKHL13, HFH-4, HFH4" ENSG00000129654 "Forkhead box J1" Q92949 17 76136333-76141245 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 43.4;choroid plexus: 80.1;fallopian tube: 53.2" "Group enriched" "Detected in many" 8 "Endometrial ciliated cells: 234.7;Respiratory ciliated cells: 124.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 73.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "BEWO: 29.9;CAPAN-2: 25.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "midbrain: 43.1" HPA005714 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA005714: AB_1078902" "prognostic favorable (9.39e-4)" "unprognostic (4.97e-3)" "unprognostic (1.22e-1)" "unprognostic (2.77e-3)" "unprognostic (1.19e-1)" "unprognostic (2.54e-3)" "unprognostic (1.71e-3)" "unprognostic (6.15e-2)" "unprognostic (1.00e-2)" "unprognostic (7.84e-3)" "unprognostic (1.43e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.03e-5)" "unprognostic (7.49e-2)" "unprognostic (1.94e-1)" "unprognostic (2.27e-1)" "unprognostic (1.91e-1)" 0.0 0.0 12.2 0.1 12.7 0.3 0.0 13.0 10.8 6.6 80.1 0.6 0.3 2.2 0.5 0.3 53.2 0.0 0.0 14.6 18.3 3.4 0.0 10.4 0.0 36.7 43.4 0.2 0.9 0.0 2.2 0.0 25.2 0.5 0.2 0.4 0.1 2.5 0.4 0.8 0.2 0.0 23.3 0.0 0.5 16.7 22.6 0.2 3.0 0.0 0.0 0.9 0.1 14.9 0.0 0.5 1.7 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 3.1 25.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 12.2 12.7 13.0 10.8 14.6 18.3 36.7 43.4 25.2 23.3 22.6 14.9 2.2 9.6 3.1 1.0 2.3 0.8 1.0 4.4 0.0 0.4 5.6 4.2 0.9 1.5 12.0 9.2 4.2 0.2 4.8 1.0 0.0 0.6 21.4 234.7 4.5 0.7 1.8 3.0 0.0 0.0 0.6 1.6 4.1 10.7 1.3 0.1 0.4 0.0 0.1 0.0 0.1 3.2 4.1 0.6 0.0 19.1 0.3 1.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.8 0.4 1.3 0.5 0.2 3.5 124.0 8.7 0.0 1.8 3.5 20.7 2.0 0.8 0.9 0.3 3.5 1.1 2.3 0.7 FOXJ2 FHX ENSG00000065970 "Forkhead box J2" Q9P0K8 12 8032716-8055517 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008723 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli fibrillar center" "HPA008723: AB_1078903" "unprognostic (1.68e-1)" "unprognostic (2.70e-1)" "unprognostic (1.22e-2)" "unprognostic (1.11e-1)" "unprognostic (1.37e-2)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (9.65e-2)" "unprognostic (3.08e-1)" "unprognostic (2.74e-3)" "unprognostic (3.40e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.63e-4)" "unprognostic (9.01e-2)" "unprognostic (2.48e-2)" "unprognostic (2.30e-2)" "unprognostic (2.02e-2)" 13.8 8.3 6.6 8.7 6.7 15.5 12.3 14.3 11.9 15.5 4.6 14.8 7.3 17.7 8.0 8.8 14.4 8.1 14.7 6.7 6.6 7.3 5.9 12.1 8.3 6.3 6.2 16.8 10.0 15.4 8.5 11.0 6.1 10.6 7.7 9.3 9.5 12.8 25.2 17.5 10.1 14.7 5.1 10.8 11.3 5.8 6.2 10.7 9.9 20.6 9.1 13.5 12.3 7.0 12.4 10.3 11.1 14.0 12.6 13.8 24.3 17.5 17.8 16.7 12.4 14.8 13.3 0.2 3.2 21.3 15.4 13.2 10.0 11.7 17.8 21.6 6.8 16.4 11.8 5.1 15.8 7.4 43.9 12.2 17.2 21.7 31.5 17.4 12.1 13.0 12.2 8.0 13.7 9.6 10.5 6.6 12.6 18.4 6.8 11.2 17.2 6.0 7.0 8.2 4.6 6.3 22.0 15.1 7.6 23.1 3.5 8.8 11.0 20.3 24.8 14.5 10.7 6.4 6.8 8.1 13.1 5.9 12.3 2.5 1.4 2.2 1.5 1.1 1.9 0.8 1.5 1.7 1.8 1.5 1.7 1.5 2.7 2.8 1.5 1.7 1.2 1.2 6.6 6.7 14.3 11.9 6.7 6.6 6.3 6.2 6.1 5.1 6.2 7.0 14.1 16.0 13.1 6.2 9.1 18.9 4.5 5.5 14.8 10.7 10.4 9.1 19.9 12.8 4.0 0.0 8.4 5.5 7.7 7.1 0.0 5.9 0.4 4.0 14.0 12.8 4.9 13.7 6.1 7.5 3.1 12.0 7.7 7.2 3.8 16.1 18.9 9.5 10.1 8.4 6.4 8.4 4.1 13.2 23.0 0.9 10.5 13.9 7.2 6.5 14.2 4.0 11.3 3.0 5.7 10.3 4.4 17.0 6.7 9.8 5.0 2.4 2.9 7.5 19.7 9.9 8.4 1.4 6.4 14.2 21.5 6.2 12.3 8.1 7.4 5.3 FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 195.3;lymphoid tissue: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 119.6;Kupffer cells: 215.3;Macrophages: 178.5;monocytes: 89.7" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4199.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 4199.5" "Group enriched" "Detected in some" 5 "LHCN-M2: 17.2;U-87 MG: 67.1" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" 69.6 10.0 3.8 166.0 4.4 195.3 5.3 4.1 8.7 8.2 5.7 4.6 3.1 3.7 0.5 8.9 15.4 28.6 7.5 3.6 8.1 4.5 21.4 50.8 12.7 15.2 8.2 2.4 11.2 5.1 3.5 45.1 11.9 3.1 3.3 2.6 4.1 2.3 1.8 1.3 5.2 42.9 8.6 129.2 5.4 2.2 9.9 8.4 3.1 22.8 10.3 66.9 2.7 18.2 0.5 0.8 0.3 0.4 1.0 2.1 0.5 0.2 0.0 0.5 2.0 0.3 0.7 1.2 0.6 0.0 3.9 0.4 0.0 0.0 0.1 0.1 0.0 0.7 0.9 1.0 6.0 0.3 0.5 4.8 0.2 1.8 1.8 9.2 0.0 0.3 0.1 0.6 17.2 0.9 0.1 0.3 0.4 0.3 0.7 0.3 0.7 0.0 1.5 0.5 0.2 0.3 0.6 0.1 0.5 0.2 1.0 1.1 1.0 2.0 0.4 0.1 3.5 0.2 0.0 0.5 67.1 1.7 0.1 317.1 759.9 204.9 1.6 319.7 1.5 0.7 1.0 0.7 174.1 1.0 1.0 1.2 4199.5 0.4 201.8 8.1 1.3 420.3 3.8 4.4 4.1 8.7 3.6 8.1 15.2 8.2 11.9 8.6 9.9 18.2 0.1 16.0 25.7 0.0 1.8 0.6 0.3 0.0 0.0 1.0 0.1 0.3 0.2 0.0 15.5 0.0 0.0 1.1 0.3 0.0 0.0 0.0 1.8 0.0 0.1 6.3 0.0 2.5 0.2 0.0 1.6 4.7 0.5 0.1 26.5 0.0 2.5 2.1 119.6 0.0 0.1 0.0 0.0 215.3 4.7 2.0 0.3 178.5 0.0 3.7 89.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.4 8.8 0.3 6.6 0.6 0.8 0.6 0.8 0.2 0.0 3.0 2.5 0.0 0.0 0.1 FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 7 "Early spermatids: 73.7;Inhibitory neurons: 126.1;Late spermatids: 144.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HEL: 163.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" 5.3 2.5 0.9 0.8 1.1 0.2 4.8 4.2 1.3 5.0 2.0 6.4 2.1 19.7 36.4 1.0 4.1 3.7 6.4 1.1 1.3 17.0 0.9 2.4 0.0 2.0 1.3 1.4 6.6 5.0 1.0 5.5 1.2 1.1 1.7 1.3 0.8 3.4 0.9 3.3 5.4 14.2 3.0 0.4 1.0 4.2 1.2 1.2 0.7 0.8 0.5 2.1 2.3 3.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.8 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.4 3.7 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 4.2 1.3 1.1 1.3 2.0 1.3 1.2 3.0 1.2 3.8 0.4 0.0 0.6 13.1 0.3 1.3 0.2 0.0 0.6 2.0 0.1 0.1 2.9 2.8 0.0 1.8 0.0 0.5 0.0 0.2 0.0 0.3 73.7 1.5 7.7 0.4 0.0 3.0 16.2 0.0 0.3 11.2 0.5 1.3 5.1 0.2 3.9 0.0 0.5 0.0 126.1 2.4 0.0 0.6 1.2 144.7 0.6 0.1 0.0 6.5 0.6 4.0 0.0 7.1 4.3 0.2 0.0 1.5 0.0 0.1 13.0 1.3 0.0 0.1 0.0 0.6 2.8 0.8 0.9 0.0 1.1 0.3 0.1 6.1 4.7 0.1 FRMD1 "bA164L23.1, DKFZp434O0117, FLJ00181, FLJ22615, FLJ40260" ENSG00000153303 "FERM domain containing 1" Q8N878 6 168053166-168101511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;lymphoid tissue: 13.1;stomach 1: 5.7;testis: 5.1" "Group enriched" "Detected in some" 4 "Distal enterocytes: 68.9;Paneth cells: 167.2" "Cancer enriched" "Detected in single" 6 "colorectal cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 1.9;RPMI-8226: 3.0" "Low region specificity" "Detected in many" HPA030347 Enhanced Approved "Actin filaments" NA NA "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "HPA030347: AB_10600207" "unprognostic (2.43e-2)" "unprognostic (2.74e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.58e-4)" "unprognostic (8.63e-2)" "unprognostic (2.62e-1)" "unprognostic (7.51e-2)" "unprognostic (9.12e-2)" "unprognostic (8.23e-2)" "unprognostic (1.71e-2)" "unprognostic (1.01e-1)" "unprognostic (9.11e-3)" 3.6 0.0 0.0 0.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 6.8 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.2 0.0 3.1 0.1 0.0 2.1 5.7 5.1 0.0 13.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 1.8 0.0 0.0 0.0 68.9 0.0 0.0 15.3 0.0 0.0 0.2 7.8 0.0 0.0 1.8 0.0 0.4 4.6 0.1 0.0 0.3 0.4 0.6 0.0 0.0 0.0 16.0 0.0 0.0 0.0 20.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.2 1.5 0.0 0.0 19.6 23.8 0.0 0.0 0.0 0.3 0.7 13.4 8.2 0.0 0.0 0.1 0.1 15.2 12.6 0.2 FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.0;skeletal muscle: 81.2;tongue: 74.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.6;Cardiomyocytes: 73.7;Cone photoreceptor cells: 79.2;Early spermatids: 121.9;Horizontal cells: 101.0;Late spermatids: 122.8;Sertoli cells: 72.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Cell line enhanced" "Detected in many" "HEL: 24.0;OE19: 49.2;RPMI-8226: 79.6;SCLC-21H: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 38: Heart - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" 9.4 7.3 6.6 2.0 5.5 5.4 6.7 4.3 6.8 3.0 12.0 5.5 2.9 2.7 15.7 2.5 2.2 2.5 85.0 6.3 7.7 14.9 0.7 4.0 1.3 10.1 8.5 1.4 1.6 20.6 4.2 14.8 7.3 2.8 6.6 21.6 2.9 7.8 81.2 2.1 6.7 3.5 7.6 7.2 2.8 9.9 9.9 1.1 7.1 74.7 0.5 4.6 2.6 5.4 0.0 4.3 3.8 0.3 0.7 0.2 0.3 4.1 0.3 0.1 0.0 0.5 5.2 0.9 4.7 1.9 0.9 0.2 0.2 0.0 0.0 0.2 0.2 24.0 4.8 2.8 0.2 0.0 0.3 1.0 0.1 0.0 0.2 0.2 2.7 0.1 0.1 0.1 4.9 0.7 0.0 0.1 0.4 49.2 7.2 0.1 3.0 79.6 6.2 10.1 28.4 13.8 1.4 0.3 0.9 0.6 1.7 0.8 4.4 0.2 0.6 0.1 2.9 0.4 0.3 0.0 0.9 7.6 2.8 0.0 2.0 0.0 0.2 3.4 0.4 0.3 0.1 0.0 0.2 0.4 0.0 0.0 2.5 0.3 1.5 0.4 0.0 6.0 6.6 5.5 4.3 6.8 6.3 7.7 10.1 8.5 7.3 7.6 9.9 5.4 38.4 22.4 1.1 6.2 0.4 1.0 1.0 0.6 0.6 108.6 2.6 1.9 73.7 15.7 1.8 1.8 79.2 0.4 0.2 28.9 17.6 2.8 121.9 2.8 1.4 25.8 1.2 0.8 37.9 2.0 1.2 8.8 2.0 3.9 0.0 0.4 4.2 0.3 0.8 101.0 70.0 38.3 0.0 4.4 0.6 122.8 2.1 8.3 0.0 27.2 4.2 3.9 1.0 10.1 16.0 2.3 10.0 4.9 0.0 1.6 43.6 12.4 3.2 7.0 72.3 66.6 50.7 4.1 1.4 0.2 1.3 0.1 0.9 29.8 2.4 2.3 FRMD4A "bA295P9.4, FLJ10210, FRMD4, KIAA1294" ENSG00000151474 "FERM domain containing 4A" Q9P2Q2 10 13643706-14462142 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 60.8" "Group enriched" "Detected in many" 7 "Excitatory neurons: 1527.6;Inhibitory neurons: 1622.8;Microglial cells: 1329.4;Oligodendrocyte precursor cells: 442.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.3" "Lineage enriched" "Detected in single" 5 "B-cells: 2.3" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 134.0;HUVEC TERT2: 105.8;TIME: 191.6;WM-115: 163.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038449 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoplasm "HPA038449: AB_10669539" "unprognostic (6.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.51e-3)" "unprognostic (5.68e-2)" "unprognostic (1.55e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.21e-3)" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (9.20e-2)" "unprognostic (1.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" "unprognostic (8.16e-2)" "unprognostic (1.84e-1)" 60.8 5.2 38.9 11.7 28.1 5.4 18.7 0.0 29.2 8.6 0.0 13.1 5.7 5.7 4.0 9.4 8.8 9.6 16.7 24.1 8.5 19.5 12.2 14.2 9.1 15.6 10.9 6.8 15.5 2.4 8.7 22.5 6.2 10.3 6.4 14.1 13.6 10.2 8.1 32.0 7.4 6.5 10.0 32.8 7.9 8.8 14.4 15.6 8.1 7.3 8.4 10.4 8.9 18.9 7.0 7.1 90.1 0.5 12.3 22.0 16.9 40.8 36.5 35.2 48.7 12.1 4.2 0.1 28.3 21.5 48.6 13.5 0.3 3.3 30.7 0.3 9.9 1.4 0.9 0.2 11.0 0.5 1.1 12.8 3.2 134.0 16.4 98.9 105.8 3.1 13.6 0.4 64.7 8.5 4.6 0.8 24.6 0.3 9.6 0.4 30.8 0.2 16.6 5.8 4.3 15.9 0.2 32.7 64.4 16.1 18.5 3.3 191.6 48.8 17.4 47.6 49.3 0.3 0.4 0.3 41.7 1.0 163.4 0.1 0.1 0.0 0.0 0.1 0.1 0.8 0.3 0.1 0.0 2.3 0.3 0.0 0.3 0.2 0.0 0.4 0.4 0.0 38.9 28.1 0.0 29.2 24.1 8.5 15.6 10.9 6.2 10.0 14.4 18.9 48.6 32.1 2.6 168.1 1.7 35.1 13.1 3.0 9.1 54.2 17.1 14.4 11.4 45.8 4.1 33.1 18.8 69.6 0.4 1.1 11.7 15.8 42.5 13.1 5.5 44.0 4.8 81.7 1527.6 4.0 42.1 14.9 4.6 26.9 15.2 58.1 44.3 6.2 35.9 80.8 1622.8 3.4 6.1 95.6 19.9 98.8 2.1 25.5 16.0 1329.4 2.7 46.0 0.0 442.3 61.0 1.8 1.4 1.9 0.9 8.0 0.3 2.7 2.5 12.9 13.1 41.2 45.5 1.3 2.1 20.6 32.7 28.7 3.0 5.3 5.4 4.3 FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 336.9" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 3633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.2;ASC diff: 9.4;NTERA-2: 7.4;SH-SY5Y: 6.5" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 44000 "Cluster 19: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.64e-2)" "unprognostic (2.38e-2)" "unprognostic (4.67e-2)" "unprognostic (8.58e-2)" "unprognostic (5.41e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (3.53e-2)" "unprognostic (1.05e-2)" "unprognostic (6.04e-2)" "unprognostic (3.21e-1)" 10.4 5.7 10.4 6.1 12.8 0.7 12.6 11.0 18.6 20.3 52.2 16.2 14.4 17.2 11.4 12.4 7.1 39.0 19.9 10.3 11.2 16.3 3.3 9.1 18.7 14.1 10.9 13.5 7.1 6.7 18.6 30.5 15.4 12.9 19.9 336.9 4.7 16.6 26.6 10.4 14.5 31.1 11.9 88.9 21.9 14.2 11.3 4.9 10.8 116.2 11.9 10.3 12.3 10.3 0.0 0.0 19.2 0.2 9.4 0.2 0.2 0.0 0.9 3.2 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 7.4 0.0 0.0 0.6 0.8 0.0 0.0 0.0 1.0 6.5 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 12.8 11.0 18.6 10.3 11.2 14.1 10.9 15.4 11.9 11.3 10.3 13.8 0.0 0.5 1.0 0.8 8.2 0.4 0.2 0.6 39.8 7.8 18.7 2.9 0.0 1.4 0.0 33.3 5.3 0.5 2.1 0.0 0.1 0.3 0.5 1.4 18.5 1.2 0.0 2.7 8.2 3.8 97.8 9.7 0.9 0.0 0.5 3.6 1.0 7.8 26.9 7.7 137.4 0.0 0.8 3.7 2.8 3.7 0.5 245.5 25.3 0.0 3633.8 0.0 8.5 1.7 0.2 0.8 14.7 5.8 1.8 1.3 0.2 0.2 124.4 276.1 41.9 157.1 0.2 0.1 0.6 3.1 12.4 1.5 22.9 3.4 0.6 FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 352.1;Fibroblasts: 521.9;Leydig cells: 327.4;Peritubular cells: 270.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 1782.4;BJ: 2156.3;fHDF/TERT166: 2692.9;HBF TERT88: 1741.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 34000000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA035251: AB_10601906, HPA040815: AB_2732489" "unprognostic (2.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.84e-2)" "unprognostic (4.54e-3)" "unprognostic (4.10e-2)" "unprognostic (1.35e-1)" "unprognostic (9.88e-2)" "unprognostic (3.05e-2)" "unprognostic (1.19e-2)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (4.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.05e-2)" "unprognostic (4.47e-3)" 432.4 134.3 20.5 116.3 18.1 2.2 166.1 22.8 22.7 279.9 83.0 156.4 37.1 157.5 50.8 126.1 150.6 257.0 242.7 20.6 22.8 45.4 35.7 120.7 50.3 28.5 44.6 90.3 37.3 35.5 25.7 442.0 23.1 188.3 90.4 29.8 59.3 184.4 31.8 64.2 69.1 409.6 22.7 63.1 68.6 33.5 22.7 24.2 78.8 89.8 38.8 260.4 104.3 20.6 81.0 21.2 222.9 91.8 1304.4 1782.4 1.3 2156.3 1208.9 1374.5 1211.0 0.1 178.5 0.8 178.8 2692.9 112.8 20.5 68.6 270.0 1741.5 1.1 32.5 0.4 159.8 0.3 286.0 1.2 0.9 1362.7 8.5 884.5 192.7 612.1 811.6 11.2 0.5 0.3 227.6 0.5 22.6 2.0 181.3 0.4 181.9 0.7 92.7 1.0 150.4 1.7 39.2 93.5 764.6 13.6 76.5 462.6 23.5 6.2 986.8 507.4 479.8 268.0 323.8 1.0 1.1 2.3 177.4 0.9 67.0 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 2.6 20.5 18.1 22.8 22.7 20.6 22.8 28.5 44.6 23.1 22.7 22.7 20.6 76.9 64.1 9.4 56.5 1.1 64.1 31.9 36.4 10.2 2.3 25.6 24.6 127.5 8.6 42.5 23.9 0.0 114.4 2.5 0.9 0.0 62.6 2.3 44.4 176.7 111.4 3.0 3.6 9.6 5.8 352.1 521.9 3.1 23.0 1.3 66.5 142.5 17.4 20.6 1.7 16.2 0.2 8.2 10.8 91.6 9.8 327.4 11.5 110.3 30.0 9.9 116.1 0.0 9.5 0.9 117.8 0.7 270.8 0.9 108.4 0.0 5.5 74.9 4.3 59.2 62.5 129.3 1.5 4.4 2.2 48.2 54.7 7.1 47.5 0.9 65.3 FSTL4 KIAA1061 ENSG00000053108 "Follistatin like 4" Q6MZW2 5 133196455-133612541 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.4" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 390.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SCLC-21H: 57.2;U-266/70: 19.3;U-266/84: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045920 Uncertain Uncertain Mitochondria "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA045920: AB_10965844" "unprognostic (5.52e-2)" "unprognostic (2.54e-1)" "unprognostic (5.74e-2)" "unprognostic (8.14e-2)" "unprognostic (1.87e-1)" "unprognostic (3.97e-2)" "unprognostic (6.35e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (4.74e-2)" "unprognostic (8.66e-2)" "unprognostic (3.73e-4)" "unprognostic (2.02e-2)" "unprognostic (9.91e-3)" "unprognostic (1.03e-2)" "unprognostic (4.25e-2)" 0.1 1.3 5.5 0.6 5.5 1.9 0.6 8.5 11.2 0.3 0.0 1.1 0.7 0.2 1.5 1.9 0.9 0.5 0.3 3.1 3.2 2.8 0.1 1.2 0.3 0.0 6.2 0.4 1.9 3.1 2.3 3.8 0.0 1.6 1.1 3.9 0.7 0.0 0.9 3.4 0.8 0.2 0.0 0.4 1.4 1.7 21.4 1.3 0.8 0.5 1.1 6.0 0.9 7.8 7.5 13.1 1.4 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 12.5 1.7 0.7 10.5 0.0 1.3 0.2 1.7 0.5 0.0 0.9 0.6 0.6 13.9 1.1 0.0 0.0 0.7 0.3 1.8 0.0 0.1 0.3 0.0 0.5 5.9 7.0 0.0 12.7 1.5 0.6 14.4 14.2 1.6 0.6 1.3 14.1 0.0 15.0 57.2 1.6 2.9 2.4 0.3 12.2 4.6 0.5 0.3 0.6 2.4 0.8 0.4 19.3 20.7 0.5 0.2 0.1 0.4 1.1 0.2 0.1 0.2 0.0 0.5 0.6 0.4 0.3 0.1 0.5 0.4 0.2 0.5 0.2 0.2 0.3 0.3 0.3 5.5 5.5 8.5 11.2 3.1 3.2 0.0 6.2 0.0 0.0 21.4 7.8 0.0 0.0 3.1 21.5 1.0 1.7 2.5 0.2 4.0 10.1 0.6 0.3 9.6 0.0 4.4 0.0 14.6 0.4 0.1 0.0 0.0 0.2 35.9 1.2 0.2 0.6 9.0 0.0 390.3 0.0 0.0 0.4 0.0 0.1 0.0 1.4 0.0 0.0 0.1 1.7 57.9 0.4 0.0 0.0 0.0 20.4 0.3 1.2 10.6 8.4 0.0 3.0 0.0 21.1 4.5 0.6 0.0 0.7 0.0 0.4 0.2 2.5 3.7 2.6 6.6 0.0 1.1 0.5 0.7 3.3 1.6 0.0 0.4 0.9 0.1 2.9 FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494812-143511720 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 165.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" NA NA 56000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA031659: AB_10600661, HPA031661: AB_10601681" "unprognostic (1.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (2.70e-9)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (7.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-3)" "unprognostic (9.18e-2)" "unprognostic (2.69e-1)" "unprognostic (7.25e-2)" "unprognostic (5.07e-2)" 28.9 41.4 13.5 25.4 16.4 25.8 26.3 16.0 15.3 29.2 30.2 41.5 42.6 25.6 44.9 14.2 23.7 27.8 27.9 12.4 16.5 54.8 52.3 28.9 17.2 17.1 14.2 30.4 34.6 165.8 15.8 50.5 17.8 21.9 52.8 6.1 25.4 25.8 6.9 12.3 39.3 27.6 16.4 24.6 38.3 12.6 15.9 6.6 32.0 11.6 17.0 33.5 20.4 20.9 97.4 55.7 47.6 86.9 69.0 134.4 90.1 89.9 95.4 108.1 182.0 107.1 94.8 0.2 66.1 120.8 33.9 0.6 24.1 11.7 148.9 87.2 92.6 32.6 100.1 163.2 99.3 0.3 15.8 72.3 69.4 96.6 41.5 91.6 111.4 0.2 117.6 49.3 123.2 114.6 0.2 75.9 62.1 44.2 76.0 0.2 99.7 72.1 129.0 59.5 36.0 23.6 98.7 65.3 82.3 36.3 32.1 79.6 65.9 64.1 54.0 161.6 175.4 18.3 21.3 0.7 74.1 59.1 22.5 38.8 84.9 26.2 13.2 84.0 15.0 11.3 9.8 11.3 65.4 8.3 4.4 7.9 5.5 29.6 62.0 10.3 19.8 51.9 13.5 16.4 16.0 15.3 12.4 16.5 17.1 14.2 17.8 16.4 15.9 20.9 27.3 41.7 35.9 9.1 13.5 11.2 12.6 30.3 9.1 3.7 19.2 12.6 28.0 38.6 37.9 25.8 0.0 52.5 10.3 47.6 11.7 81.9 2.0 26.8 55.2 25.0 9.6 18.7 8.7 124.9 109.8 62.6 34.7 28.9 37.4 38.1 23.6 35.2 110.3 1.7 11.8 38.1 46.8 57.5 29.2 2.6 66.8 51.7 42.7 9.4 49.1 11.1 13.4 5.5 14.5 74.6 38.2 45.5 47.7 13.8 60.3 51.4 34.8 1.1 6.6 33.8 35.0 4.8 4.6 13.2 8.0 46.4 11.5 78.8 50.4 18.4 FUT10 ENSG00000172728 "Fucosyltransferase 10" Q6P4F1 8 33370824-33473146 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 140.0;Early spermatids: 248.8;Late spermatids: 334.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053970, HPA058655" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Endoplasmic reticulum, Golgi apparatus" "HPA053970: AB_2682327, HPA058655: AB_2683789" "unprognostic (6.02e-2)" "unprognostic (4.61e-2)" "unprognostic (2.85e-3)" "unprognostic (6.24e-2)" "unprognostic (1.01e-1)" "unprognostic (4.80e-2)" "unprognostic (5.40e-3)" "unprognostic (6.07e-2)" "unprognostic (2.84e-1)" "unprognostic (2.23e-1)" "unprognostic (9.10e-3)" "unprognostic (2.76e-4)" "unprognostic (3.06e-3)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-3)" "unprognostic (6.01e-3)" 1.9 2.2 4.3 1.0 4.7 0.8 3.4 4.2 4.2 4.0 2.0 2.5 2.5 3.1 1.2 1.9 3.3 1.8 1.7 3.0 3.3 3.1 2.0 2.4 1.8 4.3 5.5 5.2 2.6 5.1 1.3 3.5 3.3 2.2 2.7 5.2 2.7 2.1 0.6 3.2 2.6 2.9 2.7 1.5 2.3 1.5 4.8 2.9 2.8 1.2 2.2 2.2 2.2 2.5 2.4 4.5 6.8 8.3 10.8 10.8 3.4 4.3 7.1 4.2 5.4 6.3 3.6 2.7 5.1 5.8 3.5 5.9 10.4 4.1 4.1 5.8 3.8 8.6 3.6 7.0 4.9 1.9 2.9 8.0 7.0 1.1 5.4 8.8 8.6 4.4 8.0 3.2 3.9 1.4 6.6 2.8 9.1 6.4 3.0 4.8 5.1 1.4 6.1 5.4 2.4 2.3 2.5 3.7 5.1 7.0 3.8 1.9 6.6 3.2 1.4 8.1 3.6 1.3 2.2 1.8 2.0 5.4 3.4 0.4 0.6 0.7 1.3 0.2 1.4 1.0 0.7 1.2 1.3 0.3 0.8 0.8 0.4 1.6 0.2 0.7 1.7 0.6 4.3 4.7 4.2 4.2 3.0 3.3 4.3 5.5 3.3 2.7 4.8 2.5 4.5 3.2 2.0 140.0 2.5 2.7 2.7 3.4 4.0 2.9 3.7 3.8 2.5 2.8 3.2 3.7 10.4 12.0 3.0 1.5 1.9 4.5 248.8 2.8 5.7 3.8 3.6 3.8 16.3 4.0 7.0 5.8 6.1 3.0 5.7 10.1 5.3 3.6 3.4 3.3 20.2 3.2 4.1 2.2 1.8 334.2 6.8 2.2 1.8 29.0 3.0 29.9 5.2 44.2 16.4 4.0 1.0 4.9 5.0 1.4 5.3 3.0 2.0 11.0 0.0 5.7 4.6 7.0 2.7 5.5 1.7 6.0 2.6 6.5 3.6 1.3 FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 163.9;Leydig cells: 237.9;Muller glia cells: 128.7;Peritubular cells: 363.8;Sertoli cells: 355.0;Theca cells: 141.8" "Cancer enriched" "Detected in all" 6 "glioma: 71.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cell line enhanced" "Detected in some" "AF22: 136.0;HAP1: 92.9;RH-30: 57.1;SCLC-21H: 204.5;SH-SY5Y: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA041334: AB_10970752, HPA042284: AB_2677931" "unprognostic (2.18e-3)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.31e-2)" "unprognostic (1.15e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "prognostic favorable (5.97e-4)" "unprognostic (3.44e-2)" "prognostic favorable (4.38e-5)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.60e-4)" 58.4 116.3 230.8 30.1 258.5 9.8 39.5 82.5 293.2 112.3 28.1 371.1 22.2 321.5 61.0 29.8 181.6 93.1 117.1 244.3 187.3 70.6 32.8 86.6 30.0 91.8 173.6 281.1 30.1 9.8 175.0 16.7 149.5 107.8 35.9 47.1 29.5 73.2 37.3 22.2 104.6 197.6 71.4 151.9 98.9 86.6 136.4 31.2 66.5 78.3 18.9 202.9 80.4 179.3 0.3 0.9 136.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.1 4.8 0.7 92.9 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.3 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.2 2.6 0.0 1.7 6.3 0.5 27.2 0.0 0.0 0.1 57.1 1.0 3.5 0.1 204.5 114.0 0.0 0.5 5.1 36.9 2.4 2.4 0.0 0.0 30.0 0.5 0.0 0.4 0.3 0.1 1.0 0.4 0.4 0.0 37.7 0.0 0.0 9.4 0.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.9 0.0 0.1 0.6 0.0 9.9 230.8 258.5 82.5 293.2 244.3 187.3 91.8 173.6 149.5 71.4 136.4 179.3 72.2 6.4 2.2 0.0 1.1 6.6 2.4 1.1 0.6 3.5 2.1 21.5 9.3 1.5 0.7 0.0 2.1 0.8 1.0 0.0 1.9 6.4 3.6 0.6 23.9 71.8 12.5 10.7 0.0 0.4 1.1 78.6 0.5 1.0 0.0 29.7 163.9 1.6 72.7 1.7 0.0 0.2 6.1 32.4 9.6 14.3 237.9 18.7 16.0 0.0 9.8 128.7 1.0 0.0 0.0 0.4 0.0 363.8 1.2 4.9 0.0 0.1 1.7 4.4 355.0 49.6 79.6 4.6 3.5 1.4 3.8 1.4 1.4 141.8 0.0 1.7 FYB1 "ADAP, FYB, FYB-120/130, SLAP-130" ENSG00000082074 "FYN binding protein 1" O15117 5 39105252-39274528 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.0;lymphoid tissue: 112.8" "Cell type enhanced" "Detected in many" "dendritic cells: 142.9;Extravillous trophoblasts: 88.7;Hofbauer cells: 157.0;Macrophages: 104.2;T-cells: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1670.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HEL: 61.5;JURKAT: 211.9;MOLT-4: 212.9;REH: 61.3;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025336, HPA026796, HPA067427" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 6200000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB025336: , HPA026796: AB_10964126, HPA067427: " "unprognostic (5.65e-2)" "unprognostic (2.92e-2)" "unprognostic (1.56e-2)" "unprognostic (6.26e-2)" "unprognostic (4.08e-1)" "unprognostic (3.29e-2)" "unprognostic (2.60e-1)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (5.63e-2)" "unprognostic (5.35e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (2.40e-1)" "unprognostic (4.14e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-1)" 10.2 5.8 5.7 82.5 5.5 53.0 5.1 6.3 9.3 6.6 7.4 10.0 9.1 3.8 10.5 5.7 3.6 16.8 2.4 5.4 7.9 5.0 13.6 17.6 85.8 16.7 19.1 2.7 1.8 2.1 1.5 17.9 15.8 4.2 11.0 0.5 7.4 3.0 1.2 2.0 15.0 11.6 9.3 73.0 12.2 3.3 13.3 112.8 2.6 2.7 63.0 17.1 1.8 13.9 0.2 4.2 0.0 0.0 0.5 0.0 21.1 0.1 1.2 0.3 0.4 0.4 0.3 0.3 0.0 0.0 8.0 16.4 0.0 0.3 0.1 0.3 0.0 61.5 0.0 0.1 0.0 23.3 18.6 0.3 0.4 0.0 0.4 0.1 0.0 211.9 0.0 0.0 0.0 0.0 212.9 13.5 0.2 0.1 0.1 61.3 0.0 0.3 1.0 3.5 0.1 0.0 0.1 0.5 6.5 1.4 0.0 5.2 0.0 0.0 0.2 0.2 0.2 0.4 0.0 4.5 0.0 81.4 0.2 151.3 359.0 354.6 76.3 406.5 52.9 1.8 216.7 134.5 127.6 1.3 271.7 169.8 1670.8 89.9 483.9 30.8 231.5 400.1 5.7 5.5 6.3 9.3 5.4 7.9 16.7 19.1 15.8 9.3 13.3 13.9 4.4 16.0 24.7 0.0 6.2 0.0 0.0 0.0 0.0 0.0 3.2 7.6 0.0 0.0 5.6 14.7 0.0 28.8 142.9 0.0 9.8 0.4 0.0 0.7 1.1 4.3 0.0 0.0 0.0 0.0 88.7 3.8 0.0 1.0 15.2 0.1 0.0 0.0 157.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 35.9 3.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 40.2 119.3 0.1 0.0 0.0 FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 30.9;Breast myoepithelial cells: 37.0;Cardiomyocytes: 21.1;Fibroblasts: 23.5;Proximal enterocytes: 21.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 42.8;BJ hTERT+: 48.4;CAPAN-2: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" 10.2 3.0 4.9 5.6 4.7 0.4 15.5 30.2 4.3 13.2 6.3 36.7 6.9 18.4 14.1 9.4 16.8 6.3 14.4 8.8 5.0 8.2 1.2 5.3 3.9 5.2 4.9 25.0 1.7 1.1 9.3 5.7 5.5 19.2 5.5 1.3 21.7 23.5 26.7 10.9 10.8 11.1 4.9 1.9 5.9 2.1 4.5 1.1 5.1 9.5 3.8 27.1 15.3 5.6 10.3 5.2 33.2 10.8 10.6 7.9 14.8 42.8 48.4 11.9 13.9 32.2 62.7 0.1 25.1 26.2 7.9 10.6 6.0 1.3 13.7 5.4 8.6 1.1 2.1 2.7 7.2 2.1 2.1 7.6 1.0 6.4 3.7 9.5 0.0 0.7 2.9 2.6 9.8 4.2 0.0 5.7 36.6 2.0 3.5 4.2 6.4 1.1 1.9 6.1 5.5 12.6 5.4 0.4 6.8 26.7 3.8 2.5 0.1 23.8 8.8 15.0 5.4 2.7 2.2 0.1 4.9 0.5 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.7 30.2 4.3 8.8 5.0 5.2 4.9 5.5 4.9 4.5 5.6 3.5 0.0 8.1 3.6 2.0 10.3 8.3 1.9 14.8 0.0 30.9 37.0 21.1 1.5 0.3 1.8 0.0 0.5 2.0 4.7 1.9 1.6 0.1 1.5 2.0 1.7 1.2 0.0 1.5 0.2 1.1 23.5 2.6 3.6 1.3 7.5 0.7 0.7 1.5 0.0 0.2 9.9 0.0 0.8 5.7 0.5 5.3 2.0 3.6 0.0 0.1 7.5 0.0 0.0 0.1 0.6 2.1 4.9 1.7 6.9 21.3 0.1 0.9 0.6 6.6 13.5 16.3 1.6 2.9 11.4 9.8 0.8 2.5 0.5 7.6 1.8 G0S2 ENSG00000123689 "G0/G1 switch 2" P27469 1 209675412-209676390 "Metabolic proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 796.7;bone marrow: 1345.4" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 5188.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 44.5" "Immune cell enriched" "Detected in some" 60 "neutrophil: 549.5" "Lineage enriched" "Detected in many" 213 "granulocytes: 549.5" "Cell line enhanced" "Detected in many" "ASC diff: 460.8;HBEC3-KT: 726.2;PC-3: 180.6;RPMI-8226: 242.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "unprognostic (1.67e-3)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (3.82e-1)" "unprognostic (2.21e-1)" "unprognostic (5.04e-3)" "unprognostic (3.03e-1)" "unprognostic (1.38e-1)" "unprognostic (2.32e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (7.57e-3)" "unprognostic (1.53e-2)" "unprognostic (4.78e-2)" "unprognostic (2.64e-1)" 796.7 194.3 7.0 95.7 7.5 1345.4 519.5 7.4 44.5 9.2 8.2 20.9 7.6 34.3 11.7 8.6 26.8 15.7 175.9 8.8 6.8 262.6 664.6 318.4 7.6 7.4 8.6 47.5 31.0 0.8 9.5 13.8 9.1 38.3 4.0 0.6 59.8 14.8 651.4 24.3 31.7 10.9 7.9 49.3 63.8 30.1 7.8 5.9 23.7 303.4 5.4 136.2 17.3 9.7 0.0 4.3 0.0 0.0 460.8 16.1 0.3 0.7 1.4 1.9 1.8 19.3 14.8 0.0 4.1 3.4 2.5 0.0 0.0 726.2 4.4 0.7 1.2 0.0 1.5 0.6 37.5 0.2 0.1 47.8 1.6 32.4 0.0 15.8 0.0 0.0 0.2 0.0 0.2 0.0 0.2 15.7 1.3 0.0 180.6 0.0 0.0 242.8 1.7 0.3 0.9 1.4 16.3 0.0 4.0 0.0 0.2 56.7 73.6 0.0 4.9 0.2 0.1 0.0 1.1 0.1 13.1 0.1 0.0 0.0 1.0 9.1 0.0 1.1 0.4 0.1 2.5 0.1 0.3 0.3 0.0 0.0 549.5 0.0 0.2 0.0 0.0 0.4 7.0 7.5 7.4 44.5 8.8 6.8 7.4 8.6 9.1 7.9 7.8 9.7 52.3 9.6 59.5 5.9 16.1 232.4 654.8 760.7 124.1 0.6 295.2 43.3 359.1 14.3 111.6 11.0 0.0 1.8 5.0 16.6 299.3 52.3 25.3 42.7 12.0 264.5 29.3 6.9 0.9 148.2 3.6 730.2 11.7 112.0 39.1 34.7 12.1 179.4 174.2 0.0 3.1 32.6 22.4 78.2 5188.4 12.3 114.6 1060.3 327.3 2.8 30.7 23.1 1.0 11.1 0.9 736.5 42.9 71.5 10.3 416.7 41.1 304.9 42.3 0.3 32.9 56.4 60.1 52.1 1.1 35.2 161.4 4.2 33.3 7.5 52.5 513.7 GAB1 DFNB26 ENSG00000109458 "GRB2 associated binding protein 1" Q13480 4 143336762-143474568 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 114.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 162.7;Microglial cells: 192.0;Oligodendrocyte precursor cells: 288.0;Oligodendrocytes: 1013.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 74.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034333, HPA066404" Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli fibrillar center, Plasma membrane" Cytosol "CAB034333: AB_2107855, HPA066404: " "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "unprognostic (1.66e-1)" "unprognostic (4.71e-2)" "unprognostic (1.79e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-1)" "unprognostic (1.35e-2)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.20e-1)" "prognostic favorable (3.91e-5)" "unprognostic (4.99e-2)" "unprognostic (2.70e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" 7.9 8.6 23.3 6.7 69.9 11.5 9.9 35.5 30.0 10.6 2.5 19.7 12.1 18.1 14.2 20.4 9.2 12.5 30.5 20.4 34.6 13.9 9.1 17.9 6.1 57.3 45.4 19.5 8.1 11.3 4.3 21.0 47.9 8.5 22.8 6.9 8.9 14.7 13.4 10.7 12.3 17.7 26.4 7.5 11.3 9.2 45.7 5.4 7.5 16.5 8.7 7.1 9.7 114.8 6.7 1.4 16.7 12.1 8.3 7.9 22.0 4.6 15.2 5.4 9.4 12.8 11.2 0.2 1.4 6.5 3.7 3.8 16.2 5.3 6.2 1.0 3.9 12.2 3.7 6.1 5.7 1.6 2.3 9.7 9.5 6.6 4.3 11.5 7.2 0.2 4.1 21.7 3.8 9.7 0.9 0.0 4.8 3.5 5.3 74.6 8.2 8.8 8.4 8.0 3.9 11.8 3.1 13.3 5.6 11.2 8.5 1.6 5.5 6.9 5.4 3.4 3.5 34.6 18.2 26.3 4.7 4.8 5.7 4.1 0.4 0.5 0.0 0.5 0.2 0.9 0.0 0.0 0.5 1.8 0.0 0.0 2.6 5.0 1.7 2.2 0.0 0.3 23.3 69.9 35.5 30.0 20.4 34.6 57.3 45.4 47.9 26.4 45.7 114.8 13.4 28.9 19.0 89.5 13.1 20.3 8.8 3.3 12.0 2.1 11.6 8.9 34.0 8.6 5.3 12.9 0.0 23.5 10.9 26.2 0.0 6.6 0.9 8.8 9.3 16.3 22.2 40.8 162.7 2.6 10.6 14.4 11.2 21.6 2.5 9.6 13.9 7.0 6.1 3.3 62.2 27.8 4.1 11.6 10.2 3.8 20.8 8.8 16.0 192.0 5.6 15.4 1.0 288.0 1013.6 4.9 10.7 18.8 94.4 7.2 9.3 5.4 3.4 0.8 13.1 7.0 14.3 2.0 5.3 19.9 24.9 10.4 2.7 4.4 13.6 13.5 GABRG3 ENSG00000182256 "Gamma-aminobutyric acid type A receptor subunit gamma3" Q99928 15 26971181-27541984 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 17.6;retina: 27.1;testis: 9.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 444.7;Inhibitory neurons: 615.5;Late spermatids: 351.0;Muller glia cells: 179.9" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Region enhanced" "Detected in many" "hypothalamus: 17.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.5;PC-3: 5.5;SK-MEL-30: 3.5;U-2 OS: 2.5;U-266/70: 3.2;U-87 MG: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054010 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA054010: AB_2682342" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (3.50e-2)" "unprognostic (2.61e-1)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (5.15e-2)" "unprognostic (2.95e-1)" "unprognostic (4.41e-1)" "unprognostic (1.43e-5)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" 0.0 0.4 3.5 0.2 3.0 0.0 0.4 0.0 4.2 0.8 0.0 0.0 0.0 0.1 1.9 0.0 0.4 0.0 0.0 0.9 17.6 0.7 0.1 0.0 0.6 0.5 0.2 0.0 0.0 0.0 3.0 0.0 0.0 6.6 0.0 27.1 0.8 0.2 0.0 0.3 0.0 0.0 0.6 1.0 0.0 9.3 10.2 1.0 1.5 0.0 0.8 0.0 0.2 2.9 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.4 0.3 0.0 5.5 0.0 0.0 1.0 0.0 0.0 0.1 1.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 3.2 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.0 0.0 4.2 0.9 17.6 0.5 0.2 0.0 0.6 10.2 2.9 0.1 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 4.6 2.5 1.4 0.9 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 86.2 3.2 0.1 0.3 0.0 0.0 444.7 0.0 0.0 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.0 615.5 0.0 0.0 0.0 0.0 351.0 0.9 0.2 0.0 7.5 0.0 179.9 0.0 16.1 7.9 0.0 0.0 0.7 0.0 3.1 0.0 0.3 0.0 4.6 0.0 0.1 0.1 1.6 7.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 157.4;brain: 141.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.9;Astrocytes: 34.6;Early spermatids: 26.6;Endothelial cells: 26.9;Hepatic stellate cells: 41.7;Muller glia cells: 47.4;Oligodendrocytes: 69.3" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 133.0;ASC TERT1: 128.8;HSkMC: 102.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 40000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" 157.4 4.9 45.1 1.7 55.8 2.7 87.2 62.5 49.3 12.3 14.4 21.7 3.0 11.4 11.9 12.4 24.9 5.6 18.1 47.9 90.8 11.8 4.0 9.4 4.1 137.6 60.4 22.3 3.6 2.4 3.5 32.3 130.8 6.0 3.9 13.4 25.5 4.7 36.3 41.7 21.2 7.0 102.4 12.3 15.3 9.1 62.8 4.0 18.3 35.3 1.3 33.0 22.8 141.7 0.4 1.3 0.9 1.0 133.0 128.8 0.3 3.4 2.5 0.4 1.3 0.0 0.5 0.5 1.9 7.8 2.3 0.8 0.5 1.4 2.0 0.6 1.4 1.1 1.9 0.0 7.4 1.5 0.4 102.8 0.0 1.2 1.8 2.4 2.8 0.7 0.2 3.0 1.1 1.9 0.0 2.1 0.5 0.8 1.1 0.3 1.1 24.1 0.5 0.5 0.4 0.3 0.4 1.0 0.6 0.6 0.7 1.8 3.9 0.6 4.3 26.8 0.6 1.4 5.1 1.4 2.5 0.4 0.4 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 45.1 55.8 62.5 49.3 47.9 90.8 137.6 60.4 130.8 102.4 62.8 141.7 103.9 0.0 1.7 34.6 0.1 0.5 0.4 0.0 0.0 3.8 1.1 0.9 2.8 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 26.6 0.5 3.3 26.9 0.0 0.0 4.9 0.0 0.1 24.7 0.0 1.0 1.3 0.1 41.7 1.8 0.1 0.0 3.9 0.0 0.0 0.8 2.1 16.7 1.8 0.5 0.0 22.5 0.1 47.4 0.0 5.0 69.3 0.2 0.0 0.7 1.8 2.1 0.0 0.1 0.0 3.2 0.0 7.3 2.1 25.5 0.5 0.1 0.9 0.0 0.2 0.3 0.0 0.3 GALNT7 GALNAC-T7 ENSG00000109586 "Polypeptide N-acetylgalactosaminyltransferase 7" Q86SF2 4 173168811-173323967 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 143.4;Inhibitory neurons: 172.0;Intestinal goblet cells: 126.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064243, HPA065317" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 6200000 "Cluster 5: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" Nucleoplasm "HPA064243: AB_2685223, HPA065317: AB_2685465" "unprognostic (1.81e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.53e-4)" "unprognostic (1.37e-3)" "unprognostic (1.48e-1)" "unprognostic (6.86e-3)" "unprognostic (2.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.85e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (7.65e-4)" "unprognostic (1.33e-1)" "unprognostic (4.66e-3)" "unprognostic (3.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.34e-3)" "unprognostic (5.97e-2)" 6.4 6.4 6.4 16.3 8.8 11.5 23.3 34.2 8.3 25.1 3.5 47.8 29.1 16.9 7.0 14.9 9.8 15.6 5.9 6.6 7.8 7.8 2.9 9.6 12.2 12.6 8.3 11.2 22.2 8.7 5.2 13.0 11.7 39.7 52.8 22.4 27.4 8.1 1.4 3.9 33.7 16.7 10.1 11.0 65.7 11.9 8.4 60.0 13.5 3.9 9.8 17.0 5.9 16.0 71.1 37.2 35.0 11.2 18.6 27.1 50.3 18.1 20.5 16.7 23.0 11.5 109.9 39.4 13.3 16.6 45.2 59.2 15.0 32.0 22.7 154.3 29.1 47.8 72.2 0.4 12.2 71.6 32.8 17.5 28.3 37.6 18.9 63.4 112.3 28.2 32.6 59.3 86.0 23.5 52.7 39.4 34.8 70.2 24.0 52.1 32.4 10.2 123.2 32.8 28.2 21.5 8.5 50.4 25.4 45.3 20.2 21.0 135.6 11.9 52.3 0.6 40.0 17.2 0.2 20.8 48.6 42.3 43.6 13.2 14.3 18.9 5.1 7.5 7.2 6.2 5.7 5.3 12.4 3.3 4.4 3.3 21.3 7.5 8.0 5.0 9.2 6.4 6.4 8.8 34.2 8.3 6.6 7.8 12.6 8.3 11.7 10.1 8.4 16.0 10.0 6.4 38.0 72.8 12.1 1.8 9.0 12.3 4.0 47.9 41.1 19.8 9.6 8.6 36.0 20.2 2.1 1.4 16.4 143.4 0.0 14.4 2.5 28.3 13.3 11.3 22.8 12.0 74.4 48.9 3.7 12.1 102.4 52.9 24.1 14.8 12.1 0.2 10.3 10.1 172.0 126.8 24.4 17.9 6.2 4.2 9.3 17.2 8.8 62.8 16.3 8.1 5.2 71.4 54.1 39.9 50.0 5.3 6.6 52.8 63.7 10.0 17.4 25.5 13.1 16.1 11.7 3.8 5.5 14.9 1.1 0.8 9.9 13.1 48.6 19.4 GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 31.3;testis: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 95.2;Intestinal goblet cells: 47.0;Late spermatids: 150.2" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.2;glioma: 1.8;pancreatic cancer: 0.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 23.4;U-266/84: 7.6" "Not detected" "Not detected" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA No "Cluster 22: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: AB_2686604" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" 0.4 0.6 3.2 1.8 3.3 0.0 0.6 2.7 5.1 0.5 2.0 14.0 5.7 0.3 0.1 0.1 0.6 0.0 2.5 3.2 2.8 0.4 0.2 0.3 0.2 3.4 3.2 0.7 0.2 0.0 2.8 0.1 3.3 0.4 31.3 0.2 0.4 0.3 0.1 0.2 12.6 0.8 2.9 0.5 0.5 13.5 3.3 0.0 0.2 0.0 0.0 0.4 0.3 4.1 0.0 0.0 0.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 23.4 0.0 0.0 0.0 0.1 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 3.2 3.3 2.7 5.1 3.2 2.8 3.4 3.2 3.3 2.9 3.3 4.1 0.1 6.4 0.5 1.3 0.5 0.0 0.0 0.1 0.6 2.1 0.1 2.3 4.5 0.0 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 95.2 0.5 0.1 0.5 6.6 0.0 1.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 47.0 0.0 0.0 0.0 150.2 1.5 0.1 0.0 3.7 0.2 0.5 0.0 15.1 7.4 0.2 0.6 2.6 0.0 0.1 1.0 1.0 0.0 0.6 6.6 0.7 0.1 12.3 8.3 0.0 0.0 0.0 0.8 0.3 2.2 0.0 GALNTL6 "GalNAc-T6L, GALNT17" ENSG00000174473 "Polypeptide N-acetylgalactosaminyltransferase like 6" Q49A17 4 171812254-173041559 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 7.8;lymphoid tissue: 2.5" "Group enriched" "Detected in some" 17 "Excitatory neurons: 424.4;Inhibitory neurons: 1567.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 8 "B-cells: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031019 Uncertain "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA031019: AB_10601653" "unprognostic (6.84e-2)" "unprognostic (1.28e-1)" "unprognostic (2.01e-2)" "unprognostic (5.73e-2)" "unprognostic (7.50e-2)" "unprognostic (8.32e-2)" "unprognostic (3.25e-1)" "unprognostic (9.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (2.80e-1)" "unprognostic (1.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-2)" "unprognostic (4.84e-3)" "unprognostic (1.73e-2)" 0.0 0.2 3.6 0.4 2.8 0.4 0.2 0.5 4.0 1.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.1 6.0 7.8 0.0 0.1 0.1 0.3 0.2 5.3 0.0 0.1 0.0 0.0 0.0 2.3 0.7 0.2 1.3 0.3 0.0 0.3 0.1 0.5 0.0 1.1 2.5 1.0 2.4 4.0 0.0 0.1 1.4 0.1 0.1 0.4 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.5 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 2.8 0.5 4.0 6.0 7.8 0.2 5.3 2.3 1.1 4.0 0.6 0.0 0.0 1.5 10.4 2.4 0.3 0.1 0.0 0.0 1.6 0.3 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 13.5 0.0 0.0 0.1 0.0 0.0 424.4 4.1 0.0 0.3 2.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 1567.9 2.6 0.0 1.6 0.0 21.1 0.3 0.9 5.4 13.1 0.0 0.1 0.0 57.3 9.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 1.2 0.2 1.6 1.6 0.0 0.3 0.0 0.0 0.1 0.4 0.1 GAMT "PIG2, TP53I2" ENSG00000130005 "Guanidinoacetate N-methyltransferase" Q14353 19 1397026-1401570 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 615.1;skeletal muscle: 1234.9;tongue: 466.4" "Group enriched" "Detected in many" 4 "Hepatocytes: 718.3;Proximal tubular cells: 417.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 173.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 176.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051806 Approved NA NA 420000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051806: AB_2681619" "unprognostic (3.25e-1)" "unprognostic (7.74e-3)" "unprognostic (3.22e-2)" "unprognostic (6.32e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (3.41e-2)" "unprognostic (7.10e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.54e-2)" 14.0 26.6 69.4 4.5 74.5 8.8 15.6 68.6 79.1 16.5 53.4 10.9 3.2 10.0 141.9 23.0 14.7 9.9 98.1 67.3 67.1 72.0 615.1 8.1 7.7 71.8 68.3 22.8 229.8 37.8 37.4 4.9 70.4 36.5 2.2 15.0 42.6 17.5 1234.9 32.8 6.4 4.6 68.8 10.7 31.8 55.0 76.1 24.8 22.2 466.4 4.3 12.9 15.3 94.5 21.6 24.1 25.2 56.9 30.9 37.3 34.3 25.2 41.2 31.8 28.7 54.8 15.1 11.3 17.2 30.0 3.8 9.1 39.8 15.5 8.5 81.5 46.2 34.9 20.3 176.7 18.2 0.7 11.5 41.8 5.5 33.8 0.1 44.0 6.9 43.0 50.6 26.6 52.6 22.1 103.9 12.0 28.6 10.7 75.4 103.1 22.3 81.4 38.1 19.5 8.4 58.5 1.9 14.3 32.0 16.1 65.3 48.1 12.2 34.6 35.6 1.9 11.6 119.0 24.8 19.5 32.2 46.1 40.7 3.7 2.5 15.3 18.8 3.4 27.3 22.0 26.3 23.8 11.2 32.3 40.6 30.8 1.5 18.2 6.1 47.3 15.8 14.9 69.4 74.5 68.6 79.1 67.3 67.1 71.8 68.3 70.4 68.8 76.1 94.5 9.2 0.0 7.2 5.5 18.0 58.9 42.1 57.8 116.7 41.0 60.3 99.9 99.3 127.2 12.9 16.5 56.3 35.7 15.4 0.8 92.0 39.9 5.2 6.5 7.4 9.2 7.2 35.8 7.4 33.6 41.2 30.9 10.2 4.0 4.5 43.3 18.9 718.3 81.7 18.5 10.1 1.5 6.1 29.5 13.3 16.0 83.9 13.9 32.0 3.7 4.7 57.3 10.3 4.0 36.7 13.5 0.1 139.5 12.5 24.1 0.1 417.4 6.1 61.7 32.9 77.8 47.1 4.3 22.6 42.1 42.9 12.0 19.7 31.1 3.3 23.2 GAPT "C5orf29, FLJ33641" ENSG00000175857 "GRB2 binding adaptor protein, transmembrane" Q8N292 5 58491435-58497090 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 16.9;lymphoid tissue: 42.7" "Cell type enhanced" "Detected in some" "B-cells: 84.8;dendritic cells: 160.1;granulocytes: 55.0;Macrophages: 43.0;monocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 1000.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 1000.3" "Cell line enhanced" "Detected in some" "HEL: 71.5;HL-60: 41.8;NB-4: 43.3;THP-1: 33.7;U-937: 118.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011048, HPA011070" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA011048: , HPA011070: AB_1848887" "unprognostic (9.79e-2)" "unprognostic (5.67e-3)" "unprognostic (2.39e-2)" "unprognostic (3.26e-2)" "unprognostic (3.36e-2)" "unprognostic (8.09e-4)" "unprognostic (4.32e-1)" "unprognostic (1.23e-3)" "unprognostic (4.14e-2)" "unprognostic (9.47e-3)" "unprognostic (7.28e-2)" "unprognostic (2.93e-1)" "unprognostic (3.52e-3)" "unprognostic (3.74e-2)" "unprognostic (2.42e-2)" "unprognostic (2.33e-2)" "unprognostic (1.40e-2)" 1.7 0.8 0.7 28.5 0.7 16.9 2.3 0.7 1.1 2.7 1.3 2.7 3.7 1.3 1.1 2.1 1.6 5.7 0.7 0.7 1.0 0.8 2.0 4.2 25.3 1.3 1.1 0.4 1.1 1.1 0.6 1.0 1.3 1.8 3.8 0.5 1.9 1.2 0.2 0.8 6.6 4.7 1.0 18.2 3.7 0.7 1.1 6.9 0.6 0.7 42.7 6.0 0.5 1.8 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 71.5 0.2 0.0 0.0 41.8 12.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 43.3 0.0 0.0 0.0 17.7 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 33.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 118.4 0.0 125.5 66.7 1000.3 0.4 46.5 0.5 97.0 0.4 0.4 76.8 97.4 0.3 0.3 82.0 1.4 59.3 205.4 0.3 32.0 0.7 0.7 0.7 1.1 0.7 1.0 1.3 1.1 1.3 1.0 1.1 1.8 0.4 3.2 1.9 0.0 84.8 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.2 0.0 0.6 0.0 0.0 0.0 160.1 0.0 0.0 0.0 1.6 0.0 0.1 0.9 0.0 8.8 0.0 0.0 0.1 0.4 0.5 0.0 55.0 0.0 0.4 0.0 14.3 0.0 0.0 0.0 0.0 19.4 6.0 0.5 0.0 43.0 0.0 1.9 41.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 GAS2L3 ENSG00000139354 "Growth arrest specific 2 like 3" Q86XJ1 12 100573683-100628288 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 4 "spinal cord: 13.8" HPA048593 Approved NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA048593: AB_2680455" "unprognostic (1.03e-1)" "unprognostic (5.13e-2)" "unprognostic (5.10e-2)" "unprognostic (2.70e-2)" "unprognostic (2.32e-2)" "unprognostic (1.46e-1)" "unprognostic (1.04e-7)" "unprognostic (2.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.58e-7)" "unprognostic (1.34e-1)" "unprognostic (2.35e-1)" "unprognostic (3.60e-2)" "unprognostic (6.67e-2)" 1.8 0.8 0.1 1.6 1.4 5.6 0.8 0.1 0.7 1.2 0.5 3.3 2.7 0.7 0.4 1.6 0.3 4.8 1.5 0.5 0.1 1.3 1.0 2.5 1.3 0.5 0.5 1.1 0.5 0.2 0.2 3.5 0.5 0.3 3.8 0.4 0.5 1.1 0.8 3.4 2.7 1.6 0.3 1.4 1.4 4.0 1.4 0.9 0.6 1.2 1.2 1.6 0.5 1.1 35.4 14.0 18.6 14.8 5.7 7.3 6.2 16.2 15.3 21.3 23.8 10.4 9.5 0.6 4.8 12.8 20.8 11.8 12.0 5.9 31.0 10.0 9.1 0.0 12.2 7.0 1.9 0.0 8.0 2.9 0.6 12.8 36.1 10.1 20.2 0.0 2.2 0.0 17.7 10.4 0.0 0.2 5.9 6.5 16.7 2.4 32.5 0.8 9.2 9.6 8.4 8.1 17.0 11.7 22.2 6.5 21.3 1.9 13.6 13.6 14.3 12.2 17.8 7.4 9.3 0.0 5.3 5.6 39.3 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.1 0.1 1.4 0.1 0.7 0.5 0.1 0.5 0.5 0.5 0.3 1.4 1.1 3.6 0.0 0.0 1.0 0.2 3.4 0.4 0.5 2.8 0.2 2.0 2.2 2.0 11.5 0.2 0.0 0.0 9.9 0.4 9.8 0.0 2.7 4.5 3.6 5.5 5.6 3.6 6.9 2.5 0.7 4.5 2.2 11.2 7.4 1.3 7.2 2.5 1.4 13.9 0.0 5.9 14.2 0.0 8.0 11.1 0.5 0.6 14.7 7.2 4.7 1.5 2.2 0.0 2.5 0.3 0.3 8.2 0.7 0.3 0.6 2.6 3.4 1.0 0.1 0.0 4.8 2.7 16.0 2.3 4.7 3.7 33.9 1.0 6.8 8.3 0.6 GATAD2A p66alpha ENSG00000167491 "GATA zinc finger domain containing 2A" Q86YP4 19 19385826-19508931 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006759, HPA024373" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA006759: AB_1079549, HPA024373: AB_1849522" "unprognostic (1.07e-1)" "unprognostic (2.79e-2)" "unprognostic (1.40e-1)" "unprognostic (5.64e-3)" "unprognostic (3.41e-1)" "unprognostic (1.86e-1)" "unprognostic (9.04e-3)" "unprognostic (9.53e-2)" "unprognostic (2.12e-1)" "unprognostic (2.58e-2)" "unprognostic (6.62e-3)" "unprognostic (4.69e-2)" "unprognostic (3.06e-3)" "unprognostic (4.50e-2)" "unprognostic (2.43e-1)" "unprognostic (3.30e-2)" "unprognostic (9.84e-2)" 16.7 15.1 13.1 23.6 14.0 32.6 15.4 11.0 12.6 13.6 17.1 19.5 22.8 14.8 8.7 22.0 12.3 14.4 12.3 16.7 13.5 16.1 17.1 21.7 19.8 17.6 14.4 11.4 21.6 15.1 14.9 17.8 14.3 10.7 11.3 8.4 15.5 11.0 17.9 30.0 24.8 8.3 14.4 22.2 17.8 33.0 14.8 19.5 14.7 6.9 13.6 15.1 16.4 12.7 60.7 50.8 46.5 69.3 18.9 19.7 97.5 46.7 31.6 47.7 45.4 92.8 62.6 117.9 69.5 47.1 31.6 49.6 43.6 41.5 27.6 40.6 47.7 87.1 49.4 51.8 46.2 97.6 72.1 31.3 30.2 49.9 40.0 15.8 48.2 66.9 141.1 37.1 28.1 68.5 115.9 38.7 98.3 55.8 45.9 121.9 46.6 54.9 24.9 79.0 87.7 48.9 40.4 48.6 57.5 30.2 44.0 40.3 94.9 89.9 43.3 106.8 88.5 46.1 62.9 125.3 56.2 80.9 53.7 4.6 2.9 3.2 3.2 1.5 1.9 2.3 1.9 2.7 1.3 1.5 1.4 1.6 7.8 2.7 3.3 3.0 1.3 2.3 13.1 14.0 11.0 12.6 16.7 13.5 17.6 14.4 14.3 14.4 14.8 12.7 35.7 12.8 19.2 24.5 24.1 55.7 22.3 14.2 26.2 16.1 33.5 21.5 13.5 24.3 15.4 14.7 18.8 23.7 66.3 53.4 13.7 21.9 21.8 43.9 42.8 31.4 15.6 21.0 14.9 30.6 36.8 21.9 29.0 69.5 17.1 22.1 29.3 27.9 27.7 23.5 21.4 28.9 24.4 27.3 42.1 18.5 15.5 27.7 32.0 35.6 28.5 18.2 53.5 17.1 21.6 46.4 28.8 13.9 19.5 24.1 30.2 29.9 15.8 18.3 19.7 40.5 25.8 18.4 41.4 39.5 55.5 36.7 39.3 28.2 32.2 28.2 GATM AGAT ENSG00000171766 "Glycine amidinotransferase" P50440 15 45361124-45402327 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "kidney: 2099.3;liver: 2804.2;pancreas: 2935.3" "Group enriched" "Detected in many" 8 "Hepatocytes: 1495.2;Proximal tubular cells: 3703.0" "Cancer enhanced" "Detected in all" "liver cancer: 135.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 11.0;myeloid DC: 6.6;naive B-cell: 5.4;plasmacytoid DC: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 11.0;dendritic cells: 6.8" "Group enriched" "Detected in many" 4 "RH-30: 210.1;RT4: 55.8;U-266/70: 126.3;U-266/84: 165.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026077 Enhanced Supported Mitochondria NA NA 600000 "Cluster 43: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA026077: AB_1849528" "unprognostic (1.91e-1)" "unprognostic (1.33e-2)" "unprognostic (2.77e-2)" "unprognostic (6.57e-2)" "unprognostic (9.43e-2)" "unprognostic (1.67e-2)" "unprognostic (6.99e-3)" "unprognostic (1.04e-1)" "unprognostic (4.51e-2)" "unprognostic (3.36e-2)" "unprognostic (1.33e-1)" "unprognostic (5.67e-2)" "prognostic favorable (1.38e-4)" "unprognostic (1.09e-1)" "unprognostic (4.07e-2)" "unprognostic (3.60e-2)" "unprognostic (1.80e-1)" 14.4 21.4 133.9 12.4 138.4 1.8 25.4 152.5 216.5 9.9 94.3 19.6 175.5 8.4 10.5 25.1 11.6 47.7 57.2 131.1 140.9 2099.3 2804.2 7.3 18.4 148.0 135.4 165.2 2935.3 2.7 8.3 74.7 153.4 12.4 11.5 7.5 57.5 15.1 142.5 137.6 110.2 14.5 149.2 33.6 99.2 78.2 140.4 12.6 63.0 46.9 29.7 18.0 15.5 181.2 12.9 6.5 4.4 0.6 0.1 0.2 0.8 0.1 0.1 0.0 0.2 1.4 21.4 34.4 1.0 0.0 5.7 2.2 17.0 0.6 0.4 1.9 0.3 2.8 0.4 0.3 0.8 20.7 2.6 0.8 0.7 0.0 0.4 0.0 0.3 7.8 0.4 0.7 0.2 0.6 2.2 0.6 11.2 31.3 0.0 0.5 210.1 1.5 3.5 55.8 23.5 4.1 6.9 0.4 1.2 2.1 2.9 23.7 0.0 0.0 0.5 0.2 6.3 126.3 165.5 0.8 1.6 0.3 1.0 0.0 1.1 0.3 0.2 1.6 0.0 11.0 0.0 0.2 6.6 5.4 0.0 1.4 0.0 0.1 0.6 6.8 0.0 1.0 133.9 138.4 152.5 216.5 131.1 140.9 148.0 135.4 153.4 149.2 140.4 181.2 2.4 3.2 1.1 67.3 42.3 54.3 14.9 5.2 5.7 8.1 16.9 9.5 35.5 228.8 5.4 71.7 0.0 1.0 0.8 3.1 295.4 58.2 8.8 1.3 0.4 7.3 0.0 29.3 6.8 290.0 1.2 19.8 69.8 2.7 3.8 219.5 23.9 1495.2 89.6 8.4 3.3 3.1 2.0 80.3 80.3 18.3 4.4 50.6 23.2 20.6 3.1 19.1 2.1 57.3 196.3 97.3 3.9 3.4 7.2 6.4 98.4 3703.0 1.9 3.8 6.6 38.4 16.8 22.0 9.7 16.0 133.7 1.8 17.6 4.1 3.4 20.4 GBP2 ENSG00000162645 "Guanylate binding protein 2" P32456 1 89106132-89150456 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 19.1;EFO-21: 20.3;HDLM-2: 25.9;HUVEC TERT2: 18.1;RT4: 21.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042682, CAB045975" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "CAB045975: AB_10584474, HPA042682: AB_2678113" "prognostic favorable (7.57e-4)" "unprognostic (2.92e-2)" "unprognostic (3.65e-2)" "unprognostic (3.02e-2)" "unprognostic (1.34e-1)" "unprognostic (4.68e-2)" "unprognostic (2.70e-2)" "unprognostic (1.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.75e-3)" "prognostic unfavorable (5.73e-5)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.14e-10)" "unprognostic (7.75e-2)" "unprognostic (1.65e-1)" "unprognostic (1.29e-2)" "prognostic favorable (1.10e-5)" 66.6 89.2 3.1 31.8 3.2 8.0 64.6 2.8 4.7 80.4 2.5 100.4 15.0 63.4 11.7 41.2 64.4 22.7 21.4 2.5 4.6 27.3 27.7 89.7 26.2 8.8 5.1 60.5 7.5 27.9 13.8 8.1 5.7 54.6 18.4 0.5 34.6 20.6 53.8 55.4 62.0 31.8 3.7 51.1 46.0 9.0 6.4 9.3 21.1 16.5 15.9 83.8 65.4 4.0 5.4 0.1 0.0 0.0 19.1 12.5 1.9 2.1 17.0 2.1 6.8 0.0 5.0 0.0 20.3 14.0 14.8 0.7 0.0 0.1 1.3 25.9 0.0 0.1 3.1 1.3 2.6 0.5 0.9 14.1 0.0 5.1 0.0 9.3 18.1 0.0 0.3 0.4 7.4 0.0 0.0 4.3 0.0 4.6 0.1 0.0 7.5 0.0 3.7 21.6 0.0 0.2 7.4 1.5 0.1 0.5 0.1 1.0 13.9 2.7 0.1 3.1 1.5 14.0 0.0 0.0 6.9 0.1 0.1 19.1 31.4 10.9 34.4 42.8 43.3 4.7 32.4 32.9 11.6 3.4 24.3 25.4 139.4 26.7 77.8 0.6 79.1 32.5 3.1 3.2 2.8 4.7 2.5 4.6 8.8 5.1 5.7 3.7 6.4 4.0 35.4 25.6 34.3 0.7 21.5 46.5 123.5 24.9 18.2 0.2 56.1 30.4 4.1 27.1 27.1 18.4 0.0 40.2 47.7 41.9 0.0 113.9 35.7 59.6 39.7 60.5 10.2 8.2 0.6 73.2 51.2 41.2 18.3 152.4 47.4 2.5 28.2 30.5 33.2 0.0 1.1 15.7 8.2 84.5 29.4 33.3 4.7 81.1 8.8 14.0 60.6 0.5 110.2 1.5 0.1 73.2 25.9 8.6 17.3 80.3 128.3 12.2 27.5 0.2 19.7 81.9 45.2 1.8 4.6 24.9 61.8 57.7 81.8 33.3 15.3 87.0 GBP5 ENSG00000154451 "Guanylate binding protein 5" Q96PP8 1 89258950-89272804 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 73.9" "Cell type enhanced" "Detected in many" "dendritic cells: 39.2;NK-cells: 75.2;Plasma cells: 22.9;T-cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 243.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "EFO-21: 6.5;NB-4: 10.0;U-266/70: 20.7;U-937: 31.5" "Low region specificity" "Detected in many" HPA028656 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA028656: AB_10601471" "unprognostic (2.72e-2)" "unprognostic (1.82e-2)" "prognostic favorable (9.54e-4)" "prognostic favorable (3.73e-6)" "unprognostic (8.33e-2)" "unprognostic (8.68e-3)" "unprognostic (3.71e-2)" "unprognostic (6.43e-3)" "unprognostic (2.37e-3)" "prognostic favorable (1.24e-4)" "unprognostic (3.47e-2)" "unprognostic (4.16e-1)" "prognostic unfavorable (5.53e-8)" "unprognostic (2.75e-2)" "unprognostic (3.68e-2)" "unprognostic (1.66e-1)" "unprognostic (4.11e-2)" 3.7 3.3 0.4 73.9 0.5 34.9 4.6 0.4 1.7 3.1 1.5 6.9 5.8 2.3 1.4 2.6 3.1 11.5 2.0 0.4 0.5 2.0 11.1 19.1 54.4 2.9 0.7 2.7 1.1 0.7 1.0 2.8 1.2 2.3 8.0 0.2 4.8 1.2 0.7 1.0 9.0 6.1 0.5 42.7 9.2 4.0 0.8 12.4 2.3 0.9 23.3 12.7 1.4 0.7 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.7 1.2 1.2 0.0 0.1 0.1 6.5 5.3 2.6 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.9 0.6 3.0 0.3 0.0 0.0 10.0 1.4 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.1 0.6 1.3 0.1 0.0 0.0 4.0 0.1 0.5 0.5 0.0 2.2 20.7 0.5 0.1 0.2 31.5 0.0 0.9 15.3 1.1 97.5 38.0 150.4 4.8 63.1 89.3 6.7 6.0 23.2 35.8 97.9 53.4 44.9 0.7 243.8 38.4 0.4 0.5 0.4 1.7 0.4 0.5 2.9 0.7 1.2 0.5 0.8 0.7 2.1 6.4 5.1 0.0 12.4 0.0 0.2 0.5 0.6 0.0 0.4 0.4 0.7 1.5 4.2 0.0 4.2 0.1 39.2 0.1 0.0 0.0 0.4 3.7 0.4 2.8 0.0 0.8 0.0 1.1 0.0 1.5 2.0 3.9 10.8 0.2 4.6 0.6 4.0 0.0 0.7 0.0 0.0 18.9 1.4 0.2 0.0 17.1 0.0 2.8 10.4 2.9 75.2 0.0 0.0 1.3 0.0 0.0 22.9 0.4 0.0 0.3 8.0 0.4 0.0 0.9 0.9 0.1 2.9 0.9 0.0 0.1 72.9 11.0 0.1 0.1 GCLM GLCLR ENSG00000023909 "Glutamate-cysteine ligase modifier subunit" P48507 1 93885199-93909456 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 48.5" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 207.9;Erythroid cells: 301.9;Prostatic glandular cells: 762.3;Urothelial cells: 374.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009568, HPA023696, CAB040554" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1100000 "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009568: AB_2107835, CAB040554: , HPA023696: AB_1849560" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (8.85e-3)" "unprognostic (1.56e-2)" "unprognostic (2.83e-2)" "unprognostic (4.64e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.37e-1)" "unprognostic (1.07e-1)" "unprognostic (3.53e-1)" "unprognostic (3.51e-2)" "unprognostic (3.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (2.34e-3)" 12.2 13.1 5.4 6.6 4.7 15.0 6.6 5.1 5.4 4.5 5.6 6.2 19.2 3.6 4.0 6.6 14.3 14.1 4.7 4.7 7.5 11.3 48.5 5.9 4.6 6.4 6.9 2.8 7.7 6.7 3.4 10.3 7.1 5.6 5.5 3.6 4.5 5.9 16.0 3.0 12.7 3.6 5.1 6.8 5.7 3.2 5.7 5.0 16.8 11.8 10.1 6.9 3.7 6.1 37.7 58.6 6.4 12.6 20.9 13.0 24.4 43.7 27.3 32.8 24.3 9.9 21.7 14.2 84.8 28.8 106.7 37.3 9.6 18.0 26.2 38.6 12.7 98.9 37.4 42.8 39.1 36.8 15.2 16.1 6.7 67.0 10.7 13.2 36.4 16.0 40.0 20.5 24.0 7.3 26.8 8.5 21.5 36.0 27.4 12.3 19.0 20.9 23.6 43.4 14.8 6.1 41.3 32.2 15.4 71.8 7.2 22.7 38.4 34.1 20.1 64.5 66.7 18.1 25.0 14.7 28.2 20.4 12.2 2.1 0.3 0.7 2.6 0.2 1.5 1.3 2.5 3.4 0.3 2.0 1.5 1.6 1.5 2.3 0.3 1.0 0.7 0.7 5.4 4.7 5.1 5.4 4.7 7.5 6.4 6.9 7.1 5.1 5.7 6.1 28.7 41.7 19.1 16.0 14.6 11.5 207.9 33.2 24.5 24.8 24.2 34.2 16.4 61.5 29.0 29.5 6.2 63.5 39.3 21.7 25.4 25.1 3.9 66.3 27.6 55.5 52.5 301.9 32.0 12.3 19.6 44.5 15.8 50.1 19.7 17.3 31.4 102.4 19.9 33.7 30.7 19.9 22.4 20.7 51.4 4.0 21.5 32.0 8.8 15.0 9.3 21.2 34.0 11.1 11.6 24.2 8.0 12.4 21.6 762.3 47.2 65.1 64.3 13.1 0.0 48.4 37.1 32.0 36.7 33.5 9.2 45.0 34.1 26.5 17.8 374.9 GFUS "FX, P35B, SDR4E1, TSTA3" ENSG00000104522 "GDP-L-fucose synthase" Q13630 8 143612618-143618048 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 32.1;Cytotrophoblasts: 82.1;Extravillous trophoblasts: 156.4;Hofbauer cells: 69.9;Syncytiotrophoblasts: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023361 Approved Approved Nucleoplasm,Cytosol Yes No 850000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA023361: AB_1858420" "unprognostic (1.37e-2)" "unprognostic (5.35e-2)" "unprognostic (8.62e-3)" "unprognostic (3.55e-2)" "unprognostic (2.90e-1)" "unprognostic (5.82e-2)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (8.62e-2)" "prognostic favorable (2.41e-4)" "unprognostic (6.62e-3)" "unprognostic (6.89e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (4.23e-2)" "unprognostic (2.78e-2)" "unprognostic (1.87e-2)" "unprognostic (3.27e-2)" 36.3 37.2 21.6 27.7 21.1 52.3 34.0 21.4 25.9 28.6 21.7 45.9 69.2 24.8 19.2 88.7 24.0 29.3 32.1 20.7 21.3 37.5 86.6 28.4 29.1 23.5 21.9 19.0 99.5 22.8 44.0 24.4 22.8 45.0 37.6 6.5 70.9 24.2 30.2 81.5 52.4 19.4 20.2 35.7 111.4 49.4 21.0 26.6 32.1 18.4 27.1 31.0 36.0 22.5 85.6 67.1 29.2 99.7 28.6 26.1 54.1 70.3 73.0 50.2 38.1 78.5 94.3 37.5 64.6 52.5 21.2 60.6 47.8 100.8 23.2 101.7 53.8 58.7 103.0 93.4 57.2 42.2 67.1 30.3 47.4 31.7 127.3 42.2 84.3 61.9 66.4 57.0 41.2 267.5 39.8 53.2 45.8 267.7 87.1 47.1 26.3 122.3 106.1 94.8 67.3 45.9 53.3 100.2 73.0 23.0 133.5 58.8 75.5 34.8 132.0 35.1 67.6 34.1 30.2 29.0 52.8 91.6 54.7 34.9 27.4 42.9 40.3 38.5 43.0 35.2 43.1 46.8 30.1 40.1 31.5 38.5 31.0 63.6 33.8 54.5 57.5 45.7 21.6 21.1 21.4 25.9 20.7 21.3 23.5 21.9 22.8 20.2 21.0 22.5 32.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 82.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 156.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 69.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 87.7 1.7 0.0 0.0 0.0 GGT2 GGT ENSG00000133475 "Gamma-glutamyltransferase 2" P36268 22 21207973-21227637 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 8.7;thyroid gland: 8.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 7.2;Early spermatids: 5.6;Late spermatids: 18.7;Proximal tubular cells: 3.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.6;HeLa: 3.5;Karpas-707: 1.3;U-2197: 8.9" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (4.27e-1)" "unprognostic (6.91e-2)" "unprognostic (7.03e-2)" "unprognostic (8.13e-2)" "unprognostic (1.01e-2)" "unprognostic (2.38e-5)" "unprognostic (1.05e-3)" "unprognostic (5.85e-4)" "unprognostic (7.97e-3)" "unprognostic (8.84e-2)" "unprognostic (1.16e-1)" "unprognostic (6.39e-2)" "unprognostic (2.39e-1)" "unprognostic (1.48e-2)" "unprognostic (3.46e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.7 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 1.5 0.0 0.0 0.5 0.4 0.0 0.1 0.0 0.2 1.0 0.1 0.0 8.5 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 1.6 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.3 0.3 8.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.0 3.2 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GID4 "C17orf39, VID24" ENSG00000141034 "GID complex subunit 4 homolog" Q8IVV7 17 18039408-18068405 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 69.1" "Group enriched" "Detected in many" 12 "Early spermatids: 665.5;Late spermatids: 1287.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 64.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044348 Uncertain Approved Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA044348: AB_10959602" "unprognostic (1.52e-1)" "unprognostic (4.19e-2)" "unprognostic (4.65e-1)" "unprognostic (4.67e-2)" "unprognostic (1.46e-1)" "unprognostic (1.38e-1)" "unprognostic (3.62e-1)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (8.99e-2)" "unprognostic (2.39e-2)" "unprognostic (1.28e-1)" "unprognostic (3.64e-3)" "unprognostic (2.11e-1)" "unprognostic (8.68e-2)" "unprognostic (3.58e-2)" "unprognostic (4.76e-3)" 7.6 5.1 8.3 4.7 7.7 5.8 6.0 9.6 8.6 6.7 5.0 10.0 4.2 7.3 6.5 11.6 6.1 5.1 10.1 7.5 6.6 5.9 5.5 5.3 5.5 7.7 7.6 7.8 7.6 10.5 3.0 6.5 7.7 6.7 4.6 5.7 7.9 7.9 27.7 12.4 4.6 8.5 7.0 5.7 5.8 69.1 7.8 7.2 6.7 14.4 6.0 8.8 7.3 7.7 11.8 12.1 6.7 10.9 17.2 16.8 11.4 9.6 15.6 10.5 11.8 10.2 4.5 14.9 8.1 11.3 9.6 13.1 9.8 10.6 13.7 8.1 19.6 6.6 9.5 7.5 14.9 3.9 11.1 12.5 18.6 10.5 16.3 13.9 11.8 20.9 6.0 4.1 8.6 3.0 12.8 8.4 5.9 14.4 8.8 10.8 23.9 14.8 7.2 4.6 5.0 7.6 6.5 5.7 7.2 64.9 3.6 5.0 10.0 6.7 3.8 15.7 4.9 7.3 6.7 3.2 9.6 6.7 8.8 4.3 1.1 3.6 1.2 0.6 1.3 2.6 1.1 1.2 0.9 2.0 1.3 1.4 2.9 2.0 0.8 1.6 1.9 0.6 8.3 7.7 9.6 8.6 7.5 6.6 7.7 7.6 7.7 7.0 7.8 7.7 8.7 0.0 1.1 5.2 6.0 11.1 7.5 4.5 4.6 5.8 6.4 7.0 12.4 5.7 3.1 1.8 4.2 8.3 6.1 4.1 9.8 5.3 665.5 5.4 9.5 8.4 1.2 17.2 8.2 5.7 15.2 8.0 1.1 5.5 5.7 10.7 8.2 6.8 7.3 16.8 8.1 4.9 0.0 9.5 7.7 1287.8 12.8 7.4 7.2 11.2 9.7 5.4 10.3 9.5 9.8 9.1 1.6 15.8 5.0 16.3 6.9 11.4 3.5 3.9 13.1 8.6 9.0 78.1 26.3 7.2 18.2 15.5 5.9 7.0 4.4 8.0 GIMAP1 "HIMAP1, IAN2, IMAP1, IMAP38" ENSG00000213203 "GTPase, IMAP family member 1" Q8WWP7 7 150716606-150724284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.7" "Cell type enhanced" "Detected in many" "Adipocytes: 189.8;Endothelial cells: 109.9;Hepatic stellate cells: 117.8;Kupffer cells: 109.1;monocytes: 74.9;NK-cells: 185.3;T-cells: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 14.7;MOLT-4: 9.2;TIME: 3.9" "Low region specificity" "Detected in many" "HPA044887, HPA053441" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA044887: AB_10960351, HPA053441: AB_2682152" "unprognostic (1.60e-2)" "unprognostic (6.58e-3)" "unprognostic (8.21e-3)" "unprognostic (2.54e-3)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "prognostic favorable (1.09e-4)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.44e-1)" "unprognostic (4.60e-3)" "unprognostic (7.89e-2)" "unprognostic (1.77e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-1)" 9.8 2.5 3.0 11.0 3.0 1.0 7.9 2.9 3.5 3.8 3.0 3.7 3.5 4.6 1.1 2.1 4.4 3.2 9.3 2.8 2.9 3.5 2.4 8.9 19.6 3.5 3.2 1.5 1.4 1.5 1.1 7.1 3.4 2.3 2.2 0.1 2.5 2.0 5.4 2.5 6.9 3.8 3.5 24.7 3.3 0.8 3.6 6.6 5.3 7.1 8.4 3.5 3.0 3.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.7 1.9 0.0 0.0 0.0 0.0 9.2 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 3.0 32.2 0.1 43.8 29.6 51.1 0.3 47.5 54.2 13.5 0.6 68.2 56.2 2.7 42.6 30.6 0.8 34.0 35.0 3.0 3.0 2.9 3.5 2.8 2.9 3.5 3.2 3.4 3.5 3.6 3.2 189.8 3.2 1.5 0.0 5.1 5.5 0.6 0.0 1.2 0.6 1.9 3.6 5.9 2.8 0.6 0.0 0.0 0.3 51.5 0.1 0.0 0.3 0.3 0.4 0.6 109.9 0.0 10.5 0.0 0.4 0.3 3.7 1.5 0.2 8.2 0.2 117.8 2.0 37.9 0.0 0.0 0.0 0.0 109.1 7.6 1.3 1.5 48.0 8.8 0.0 74.9 0.3 185.3 0.0 0.0 0.1 0.1 0.0 7.6 0.7 0.2 0.5 0.0 1.0 0.0 2.5 3.5 0.3 0.5 0.7 3.1 0.4 97.3 1.0 0.0 0.7 GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 195.2;Hepatic stellate cells: 222.0;Kupffer cells: 197.2;Macrophages: 110.0;monocytes: 176.0;NK-cells: 344.0;T-cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 26 "HUVEC TERT2: 326.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" 46.1 18.3 15.0 75.1 15.6 4.2 31.8 16.2 21.2 19.7 16.3 21.2 16.5 23.0 9.6 12.0 18.7 24.6 31.3 14.3 16.0 17.3 29.9 50.8 127.7 19.2 18.0 7.7 6.7 9.6 6.0 48.7 18.0 10.2 22.4 1.5 11.2 13.3 17.5 8.4 25.0 38.3 18.8 115.6 18.0 4.2 16.4 30.5 21.1 48.1 85.1 31.1 11.6 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 326.4 3.4 0.1 0.3 0.0 0.0 0.4 0.2 0.4 0.0 0.0 12.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 370.2 5.2 325.8 390.9 404.2 3.0 408.0 402.8 122.1 1.3 424.3 361.9 339.7 263.4 320.4 5.3 312.1 776.9 15.0 15.6 16.2 21.2 14.3 16.0 19.2 18.0 18.0 18.8 16.4 18.7 182.3 3.2 12.4 0.3 7.3 6.8 0.2 0.0 3.4 0.1 2.2 4.7 9.9 5.7 1.8 11.0 0.0 0.6 82.6 0.0 0.0 0.2 0.6 0.3 0.4 195.2 0.0 9.7 0.5 0.2 0.8 9.0 2.0 0.3 6.3 0.0 222.0 3.7 96.4 0.0 0.1 0.0 0.0 197.2 20.9 1.7 5.0 110.0 10.6 18.7 176.0 0.2 344.0 0.0 0.1 0.1 0.0 0.0 14.7 0.4 0.0 1.9 0.7 0.4 13.1 3.9 7.9 0.0 0.8 1.1 6.1 0.8 186.2 0.8 0.0 0.3 GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.1;Basal keratinocytes: 11.1;Endothelial cells: 29.7;Langerhans cells: 13.9;Suprabasal keratinocytes: 10.7;T-cells: 31.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "MOLT-4: 41.7" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.77e-2)" "unprognostic (8.83e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-3)" "unprognostic (6.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.13e-1)" "unprognostic (7.15e-3)" "unprognostic (1.86e-1)" "unprognostic (1.47e-2)" 34.4 13.6 13.3 44.8 14.2 5.2 25.5 13.7 16.8 15.9 12.7 16.6 10.6 17.1 8.8 12.4 18.9 17.9 24.2 12.8 13.2 12.7 23.3 39.7 106.2 15.2 14.1 5.9 8.7 9.1 4.1 26.4 14.8 6.6 16.5 0.8 7.2 9.0 12.4 7.2 22.1 30.5 14.2 64.2 15.6 3.5 14.7 25.1 18.3 43.9 66.4 26.7 6.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.3 0.0 1.4 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.4 0.0 3.6 70.5 1.1 260.4 106.3 337.2 1.1 436.3 334.0 8.0 0.6 521.5 280.6 8.3 188.3 43.6 1.6 176.9 510.2 13.3 14.2 13.7 16.8 12.8 13.2 15.2 14.1 14.8 14.2 14.7 13.8 22.1 0.0 1.7 0.0 1.4 11.1 0.3 0.0 1.2 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.1 5.8 0.2 0.0 0.0 0.1 0.0 0.1 29.7 0.0 0.4 0.0 0.0 0.4 2.6 0.5 0.1 2.5 0.0 8.9 0.6 3.1 0.0 0.0 0.2 0.0 5.3 13.9 0.1 0.0 7.1 3.6 0.0 2.2 0.0 9.2 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.1 0.1 0.0 0.1 0.0 0.7 3.2 0.2 0.1 0.1 10.7 0.3 31.5 0.1 0.1 0.1 GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 265.8;Endothelial cells: 263.3;Hepatic stellate cells: 267.4;Kupffer cells: 156.8;monocytes: 140.8;NK-cells: 632.4;T-cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 92.9;MOLT-4: 78.6" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" 49.8 15.0 16.3 73.6 17.4 6.6 37.4 17.1 21.3 19.2 16.0 20.3 21.1 27.8 19.8 12.6 21.5 22.1 40.1 15.5 17.2 20.9 20.4 61.0 170.1 19.0 17.8 7.4 7.6 10.5 5.6 31.5 19.1 10.9 23.3 1.2 13.7 12.0 27.8 9.3 40.1 33.6 17.6 124.3 22.0 4.5 18.0 52.5 28.2 56.1 99.2 29.6 13.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 92.9 9.4 0.0 0.0 0.0 0.0 78.6 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.7 656.5 9.6 1184.0 595.9 1164.2 6.5 1762.9 1440.6 286.3 6.5 2269.3 1597.2 52.5 1121.0 666.6 16.3 1076.9 2581.7 16.3 17.4 17.1 21.3 15.5 17.2 19.0 17.8 19.1 17.6 18.0 17.6 265.8 0.0 13.2 0.3 13.1 2.4 0.4 0.0 2.8 0.0 2.8 5.6 14.6 5.7 0.6 1.8 0.0 0.2 125.1 0.2 0.0 0.5 1.3 0.9 0.6 263.3 0.0 17.0 0.0 0.7 0.0 8.0 3.1 0.7 13.9 0.0 267.4 5.3 15.5 0.0 0.0 0.1 0.0 156.8 10.6 2.0 2.5 54.9 1.8 22.5 140.8 0.4 632.4 0.5 0.1 0.4 1.2 0.4 19.3 0.2 0.0 1.7 0.7 0.4 0.0 6.0 9.4 0.2 0.9 1.1 3.3 0.4 255.9 0.9 0.2 0.0 GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.6" "Cell type enhanced" "Detected in many" "Adipocytes: 67.4;Endothelial cells: 66.0;Hepatic stellate cells: 86.0;Kupffer cells: 75.1;Microglial cells: 32.8;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 59.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA014474: AB_1849685, HPA017765: AB_1849683" "unprognostic (7.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.04e-1)" "unprognostic (4.42e-3)" "unprognostic (2.11e-1)" "unprognostic (8.09e-3)" "unprognostic (1.07e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (6.26e-3)" "unprognostic (2.15e-1)" "unprognostic (1.04e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" 20.3 5.7 4.4 21.3 5.0 0.7 16.0 4.7 5.5 9.8 5.5 6.7 6.8 10.4 3.1 4.3 9.0 7.5 17.4 4.1 4.5 8.3 9.4 27.0 23.2 5.4 4.9 3.5 2.8 4.6 2.6 15.4 5.4 4.9 7.2 0.3 4.3 5.3 9.8 4.7 10.5 12.7 5.4 40.6 5.0 2.0 5.1 7.3 11.9 15.1 13.5 8.4 5.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 59.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.7 0.0 9.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.5 45.2 0.0 15.3 59.0 17.4 0.5 14.8 13.9 13.0 0.0 16.7 13.6 4.8 15.5 57.4 0.7 7.7 26.8 4.4 5.0 4.7 5.5 4.1 4.5 5.4 4.9 5.4 5.4 5.1 5.8 67.4 3.2 5.3 0.3 0.8 3.1 0.5 0.0 1.8 0.0 0.4 0.8 5.5 5.7 0.0 1.8 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.2 0.1 66.0 0.0 1.3 0.1 0.0 0.0 2.3 0.5 0.2 3.8 0.0 86.0 1.6 6.8 0.0 0.1 0.0 0.0 75.1 2.8 0.9 0.3 21.9 0.0 32.8 44.2 0.0 19.6 0.0 0.1 0.0 0.0 0.0 2.2 0.9 0.0 0.2 1.5 0.0 0.0 1.5 1.2 0.2 0.4 0.5 1.7 0.1 11.1 0.2 0.0 0.4 GINS2 "Pfs2, PSF2" ENSG00000131153 "GINS complex subunit 2" Q9Y248 16 85676198-85690073 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 163.5;Spermatogonia: 148.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 271.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA057285 Uncertain Approved Nucleoplasm No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA057285: AB_2683398" "unprognostic (3.22e-2)" "unprognostic (1.13e-3)" "unprognostic (2.04e-3)" "unprognostic (2.09e-1)" "unprognostic (2.64e-1)" "unprognostic (1.30e-1)" "unprognostic (2.45e-3)" "unprognostic (2.58e-2)" "unprognostic (1.67e-2)" "unprognostic (2.52e-3)" "unprognostic (2.19e-2)" "unprognostic (5.82e-3)" "unprognostic (5.70e-3)" "unprognostic (4.54e-2)" "unprognostic (6.30e-2)" "unprognostic (5.44e-3)" "unprognostic (1.60e-1)" 1.0 0.9 3.0 5.4 2.8 14.7 3.7 3.0 3.7 1.7 2.2 6.4 4.6 1.6 1.3 4.7 1.1 0.4 0.6 4.5 2.2 0.7 3.0 0.8 9.0 2.3 2.4 1.4 0.9 2.6 0.8 3.0 2.3 1.5 7.0 11.1 1.3 0.8 2.7 3.2 5.3 1.6 2.3 3.0 2.2 9.6 2.3 10.2 1.8 1.0 11.0 1.4 2.1 2.6 50.7 36.2 69.0 28.9 2.0 6.7 18.3 33.8 13.7 49.8 30.5 48.2 32.9 60.0 18.1 12.0 26.0 38.0 73.7 28.1 47.9 20.8 63.9 29.2 25.7 54.6 0.3 20.6 15.6 1.8 3.4 30.0 11.5 6.1 21.6 47.5 82.4 13.8 28.9 107.1 72.7 77.8 38.8 45.0 27.3 100.7 41.5 33.1 16.4 20.9 94.2 30.0 49.4 10.0 10.0 27.3 100.0 28.2 12.8 32.1 42.5 30.6 39.5 25.6 48.3 271.9 18.7 43.4 37.2 0.7 0.2 1.1 1.0 1.0 0.1 1.0 3.3 2.3 1.3 0.7 1.6 1.1 0.9 3.2 2.8 0.8 8.5 1.7 3.0 2.8 3.0 3.7 4.5 2.2 2.3 2.4 2.3 2.3 2.3 2.6 0.6 3.2 0.0 0.7 8.5 9.2 7.4 9.5 4.0 20.3 13.1 18.5 1.0 0.0 3.8 3.7 2.1 35.3 3.1 11.9 3.9 8.2 9.8 1.5 3.3 2.4 3.0 43.3 0.5 1.5 31.8 7.2 5.6 2.7 1.3 21.6 0.0 2.1 23.8 8.4 0.4 14.9 4.1 1.3 6.6 29.4 1.2 3.3 0.0 0.0 1.1 5.6 0.0 1.0 0.6 2.0 4.5 1.9 43.1 2.6 2.4 0.7 1.7 7.5 19.7 4.2 7.9 163.5 148.4 13.8 3.8 12.7 4.2 2.2 33.6 7.4 GIPC1 "C19orf3, GIPC, GLUT1CBP, Hs.6454, NIP, RGS19IP1, SEMCAP, SYNECTIN, TIP-2" ENSG00000123159 "GIPC PDZ domain containing family member 1" O14908 19 14477760-14496149 "Human disease related genes, Predicted intracellular proteins" "Congenital muscular dystrophy, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 345.8" "Cell type enhanced" "Detected in all" "Distal enterocytes: 501.1;Pancreatic endocrine cells: 296.7;Paneth cells: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043958, HPA061786" Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 11000 "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA043958: AB_10963436, HPA061786: AB_2756319" "unprognostic (2.80e-1)" "unprognostic (1.16e-1)" "unprognostic (8.21e-2)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-1)" "unprognostic (1.18e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (4.82e-2)" "unprognostic (3.53e-2)" "unprognostic (7.72e-2)" "unprognostic (1.04e-2)" "unprognostic (7.17e-3)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" 51.0 54.8 80.0 22.4 91.5 3.3 54.3 88.7 94.4 99.8 64.7 120.2 24.7 53.7 17.6 345.8 48.9 23.4 66.1 74.5 82.1 104.1 58.4 76.3 15.9 89.4 91.4 34.4 43.5 20.8 56.0 28.7 88.1 63.6 41.1 17.9 100.9 31.0 65.1 150.2 45.5 17.5 82.0 37.7 78.7 24.9 91.1 18.6 55.8 23.3 21.0 74.1 140.1 92.3 328.1 148.6 44.7 70.6 40.6 40.7 35.2 119.7 59.8 96.7 87.3 80.3 120.6 4.7 220.3 85.2 64.6 183.8 38.7 100.6 32.6 33.8 69.0 63.9 100.7 79.7 123.7 6.9 75.3 46.7 98.5 58.8 51.3 57.4 66.0 47.2 30.1 54.4 49.9 243.8 21.3 13.3 48.6 182.1 147.8 21.7 37.4 43.7 121.6 281.6 41.8 46.2 67.1 163.2 157.0 23.1 102.5 35.1 115.4 135.7 74.6 191.7 130.1 50.5 70.5 17.3 113.9 51.9 146.2 3.0 0.7 0.1 5.1 1.1 4.7 1.9 5.1 5.1 1.1 0.8 4.2 3.3 0.3 1.5 0.5 3.6 12.0 1.7 80.0 91.5 88.7 94.4 74.5 82.1 89.4 91.4 88.1 82.0 91.1 92.3 30.6 28.9 15.2 22.9 8.3 113.9 77.4 52.1 35.9 69.8 73.6 31.6 14.8 37.1 62.8 82.8 35.5 36.3 19.3 501.1 52.8 167.9 1.1 92.2 30.5 32.4 43.1 1.7 28.8 164.3 77.1 32.6 69.3 76.8 10.2 37.3 23.2 18.0 55.9 75.7 32.2 87.8 42.7 10.8 29.8 2.4 20.5 16.1 58.7 10.3 23.4 73.3 18.6 17.1 71.6 296.7 285.4 25.2 6.8 120.4 36.0 52.7 38.0 46.0 19.7 18.1 44.5 6.4 20.4 107.0 169.8 25.7 22.9 47.7 138.1 199.7 GIPC2 "FLJ20075, SEMCAP-2" ENSG00000137960 "GIPC PDZ domain containing family member 2" Q8TF65 1 77979542-78138444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.0;kidney: 41.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 122.1;Proximal tubular cells: 267.7;Undifferentiated cells: 63.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.1;HaCaT: 6.0;Hep G2: 23.0;HUVEC TERT2: 23.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051212, HPA062684" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA051212: , HPA062684: AB_2684833" "unprognostic (1.72e-2)" "unprognostic (9.37e-2)" "prognostic favorable (5.49e-4)" "unprognostic (1.09e-2)" "unprognostic (1.43e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.35e-1)" "unprognostic (7.63e-2)" "unprognostic (2.22e-1)" "unprognostic (5.91e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.11e-6)" "unprognostic (6.55e-2)" "unprognostic (1.78e-1)" "unprognostic (4.18e-2)" "unprognostic (1.29e-1)" 3.9 23.8 0.5 1.7 0.4 0.3 3.0 0.4 0.5 1.8 0.5 15.6 38.0 2.1 0.9 2.1 3.1 5.5 1.5 0.5 0.4 41.4 18.4 2.7 0.8 0.4 0.4 2.4 18.1 2.3 0.9 3.5 0.4 1.7 14.9 0.1 4.2 0.9 1.1 4.7 38.0 2.8 0.4 27.9 6.0 1.0 0.5 0.4 1.0 1.6 0.8 2.0 1.9 0.4 0.0 0.0 0.0 0.1 2.4 6.1 0.0 1.0 0.0 0.5 1.1 5.1 3.3 1.5 0.1 0.5 0.0 6.0 0.0 0.0 3.2 0.2 0.0 0.8 0.0 23.0 1.2 0.0 0.0 1.0 0.1 3.5 0.1 0.0 23.5 0.0 0.0 0.1 2.9 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.5 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.4 33.6 0.0 1.3 2.0 2.0 12.9 2.4 0.9 4.0 0.4 5.2 1.5 3.2 27.1 2.5 9.2 2.1 6.7 0.0 43.7 33.2 11.8 2.5 13.3 0.9 21.6 3.0 0.4 14.7 33.0 3.1 2.9 8.6 7.2 0.0 5.9 22.9 43.3 13.2 0.0 15.2 34.4 0.0 0.8 1.9 1.2 1.2 2.1 0.0 14.0 1.0 0.0 0.0 4.5 8.9 16.5 39.3 0.0 0.0 0.8 122.1 267.7 11.7 0.5 0.0 1.3 1.3 0.6 2.5 7.9 21.7 1.6 1.3 32.4 63.8 6.0 GIPC3 "C19orf64, DFNB15, DFNB72, DFNB95" ENSG00000179855 "GIPC PDZ domain containing family member 3" Q8TF64 19 3585478-3593541 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 16.7" "Group enriched" "Detected in some" 4 "Adipocytes: 10.4;Endothelial cells: 6.2;Hepatic stellate cells: 12.8;Rod photoreceptor cells: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 19.0;HMC-1: 11.8;THP-1: 23.1;WM-115: 44.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA067765 Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA067765: " "unprognostic (1.77e-1)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (6.99e-2)" "unprognostic (1.22e-1)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (3.67e-3)" "unprognostic (4.76e-2)" "unprognostic (2.97e-1)" "unprognostic (5.06e-3)" "unprognostic (2.26e-2)" "unprognostic (1.51e-3)" "unprognostic (1.96e-2)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (9.06e-2)" 4.6 2.2 1.4 1.0 1.0 0.3 2.8 1.0 1.1 3.0 0.8 1.9 1.2 2.8 2.9 5.2 2.1 2.1 3.9 1.2 1.2 3.6 1.4 3.8 2.4 1.6 1.2 0.7 0.7 2.7 1.0 1.1 1.6 3.5 1.4 16.7 0.7 2.3 1.7 1.1 4.4 8.3 1.4 3.9 2.0 0.3 1.6 3.1 3.0 1.9 1.6 1.1 1.8 1.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.1 0.9 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.4 0.0 1.5 0.0 0.2 6.9 19.0 0.0 0.7 0.0 11.8 0.2 0.0 1.1 0.0 0.0 2.1 0.2 3.2 0.0 0.3 0.0 0.0 1.1 0.7 0.0 1.2 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.5 0.0 4.7 1.1 0.0 23.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 44.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 1.0 1.1 1.2 1.2 1.6 1.2 1.6 1.4 1.6 1.1 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.4 0.1 0.3 2.4 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 12.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.8 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.2 1.1 0.0 0.4 0.1 0.3 0.1 0.3 0.1 0.0 0.1 GJC3 "CX30.2, GJE1" ENSG00000176402 "Gap junction protein gamma 3" Q8NFK1 7 99923266-99929620 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 8.7;pancreas: 11.1;salivary gland: 11.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 36.3;Breast myoepithelial cells: 26.9;Exocrine glandular cells: 24.0;Pancreatic endocrine cells: 12.8;Prostatic glandular cells: 13.0" "Group enriched" "Detected in many" 5 "breast cancer: 3.8;melanoma: 3.0;prostate cancer: 3.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.3;SK-MEL-30: 2.3;U-2197: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015024 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" "HPA015024: AB_1847132" "unprognostic (9.31e-2)" "unprognostic (6.43e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-2)" "unprognostic (2.54e-1)" "unprognostic (2.88e-2)" "unprognostic (7.68e-2)" "unprognostic (9.14e-2)" "unprognostic (6.71e-2)" "unprognostic (4.78e-2)" "unprognostic (1.20e-1)" "unprognostic (3.88e-3)" "unprognostic (1.14e-1)" "unprognostic (4.17e-1)" "unprognostic (3.49e-1)" "unprognostic (5.81e-3)" 1.6 0.5 0.8 0.1 0.9 0.1 8.7 0.1 1.2 0.3 0.0 0.5 0.4 0.2 0.0 0.2 0.3 0.3 0.4 0.9 0.3 1.0 2.7 0.2 0.2 0.2 0.4 0.4 11.1 0.0 0.4 1.0 0.2 4.6 0.0 1.0 11.7 0.1 0.2 2.6 0.3 0.2 0.0 0.3 1.4 1.7 0.6 0.1 0.3 0.2 0.0 0.3 0.3 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.5 0.6 0.1 0.5 0.2 0.4 1.1 1.3 0.0 0.0 0.4 0.3 0.0 0.4 0.1 0.2 0.1 0.3 2.3 0.5 0.7 0.0 0.3 0.1 0.4 1.8 0.1 0.1 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.9 0.1 1.2 0.9 0.3 0.2 0.4 0.2 0.0 0.6 0.5 1.1 3.2 3.7 0.0 0.4 0.3 4.9 1.4 0.0 0.0 36.3 26.9 0.0 4.3 2.1 1.8 0.0 0.0 0.6 0.0 1.9 0.4 0.4 0.0 0.0 1.5 1.2 0.0 0.7 24.0 0.0 0.2 0.0 0.0 4.5 0.2 1.1 5.0 0.1 0.0 0.4 0.1 8.2 0.0 0.3 1.1 0.3 0.1 0.0 0.0 0.6 4.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 13.0 0.0 9.7 0.3 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 9.4 GLE1 "GLE1L, hGLE1, LCCS1" ENSG00000119392 "GLE1 RNA export mediator" Q53GS7 9 128504719-128542288 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.0;Late spermatids: 58.1;Spermatocytes: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041689, HPA043538, HPA061560" Supported Supported "Nuclear membrane,Nucleoli" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear membrane" Nucleoli "HPA041689: AB_2677617, HPA043538: AB_2678539, HPA061560: AB_2684560" "unprognostic (8.74e-3)" "unprognostic (2.18e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.49e-4)" "unprognostic (1.75e-1)" "unprognostic (5.58e-2)" "unprognostic (7.91e-2)" "unprognostic (1.90e-1)" "unprognostic (1.91e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.95e-2)" "unprognostic (4.00e-2)" "prognostic favorable (7.04e-4)" "unprognostic (2.62e-1)" "unprognostic (1.99e-3)" "unprognostic (5.64e-2)" 11.6 14.0 9.2 15.7 9.2 15.1 15.7 12.4 11.3 13.0 13.4 17.4 16.2 11.6 10.8 16.4 14.1 7.8 14.9 8.9 8.8 14.1 16.3 12.3 20.4 8.7 9.2 16.2 9.5 17.6 14.1 9.2 8.6 11.8 18.3 16.5 11.1 12.4 22.5 19.1 15.8 12.9 8.4 15.2 12.9 32.0 9.3 25.9 13.3 12.4 22.2 12.8 12.3 8.9 29.6 54.5 26.2 44.9 25.3 25.5 34.6 29.2 24.9 40.2 28.4 36.8 20.1 59.6 23.0 33.0 38.6 101.4 45.9 41.7 34.5 56.9 29.8 30.6 57.8 34.6 28.5 49.9 38.8 18.1 39.7 45.6 48.5 22.3 22.9 54.7 44.7 51.0 46.7 68.6 49.5 35.2 22.2 79.1 46.7 49.8 64.2 79.0 27.3 26.1 30.9 23.1 71.3 42.7 25.9 21.1 78.9 34.9 17.0 42.5 28.1 50.2 41.2 50.9 131.9 45.9 39.9 37.5 46.8 40.0 21.1 24.4 22.1 26.0 18.1 13.4 17.2 20.0 22.1 20.5 15.2 17.7 18.0 27.4 27.5 13.0 22.3 19.8 9.2 9.2 12.4 11.3 8.9 8.8 8.7 9.2 8.6 8.4 9.3 8.9 4.0 9.6 9.0 11.1 11.4 6.5 5.3 10.4 8.6 7.6 8.8 7.6 13.0 5.7 7.2 7.3 8.4 16.1 6.9 13.2 5.9 11.7 77.0 12.2 7.4 3.6 5.4 12.0 14.0 6.2 11.7 7.6 10.2 9.4 9.5 10.9 4.6 14.2 15.7 10.1 15.5 12.7 8.2 15.1 5.7 58.1 10.2 13.5 3.6 10.3 20.0 8.9 15.5 18.1 15.5 8.3 8.0 6.4 13.4 6.1 16.3 13.7 12.6 8.6 13.1 7.7 7.3 51.3 25.5 14.4 6.8 13.3 12.1 7.1 14.1 5.4 GLIPR2 "C9orf19, GAPR-1" ENSG00000122694 "GLI pathogenesis related 2" Q9H4G4 9 36136536-36163913 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 188.5;Langerhans cells: 203.6;Macrophages: 117.6;monocytes: 203.0;NK-cells: 180.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 71.6;HDLM-2: 72.9;TIME: 127.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029478 Approved Uncertain Vesicles,Microtubules NA NA 19000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Microtubules "HPA029478: AB_10670038" "unprognostic (1.57e-2)" "unprognostic (5.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.46e-2)" "unprognostic (1.33e-2)" "unprognostic (9.90e-2)" "unprognostic (2.50e-1)" "unprognostic (1.84e-2)" "unprognostic (4.26e-2)" "unprognostic (3.21e-1)" "unprognostic (5.87e-2)" "prognostic unfavorable (6.54e-7)" "unprognostic (6.57e-3)" "unprognostic (4.94e-1)" "unprognostic (1.02e-1)" "unprognostic (2.43e-2)" 38.5 20.9 17.6 52.7 22.8 73.8 32.4 21.0 22.6 45.9 14.1 73.7 14.7 77.8 15.1 18.6 36.9 24.1 24.2 17.2 19.3 8.8 6.9 62.6 29.9 24.8 22.1 13.3 5.6 2.5 4.9 8.8 22.3 38.3 33.1 2.7 15.3 39.3 7.7 12.2 32.2 63.8 22.8 41.3 25.3 3.4 26.7 18.7 15.8 11.1 19.2 38.8 27.4 27.6 3.7 2.9 20.9 22.3 71.6 33.3 2.4 32.9 20.0 7.8 14.1 1.3 0.3 0.2 10.2 30.9 19.7 0.2 7.9 1.1 4.7 72.9 6.4 8.8 6.2 0.4 27.9 5.7 28.3 23.4 1.0 44.5 7.8 14.0 62.5 22.6 0.4 5.0 17.4 7.9 27.9 15.2 20.1 0.3 10.7 18.9 44.1 1.0 1.6 1.8 5.6 11.3 4.4 2.2 3.6 42.2 2.3 24.0 127.3 10.7 24.8 9.6 28.0 7.8 2.2 12.7 11.0 35.0 2.5 268.6 360.9 540.3 168.4 162.5 89.1 24.4 114.3 108.2 208.3 24.5 47.0 74.7 657.0 125.5 124.9 18.5 132.2 414.0 17.6 22.8 21.0 22.6 17.2 19.3 24.8 22.1 22.3 22.8 26.7 27.6 11.9 3.2 25.4 4.6 22.3 13.4 2.5 14.7 1.8 0.3 46.9 19.0 2.6 2.8 30.9 5.5 0.0 3.8 66.9 14.7 0.0 21.2 0.7 1.8 33.9 13.3 8.4 58.7 1.1 1.3 3.3 54.3 11.7 2.1 52.6 1.9 16.1 0.9 188.5 0.0 0.8 42.4 14.2 83.2 203.6 2.3 18.0 117.6 62.2 2.8 203.0 21.4 180.2 3.0 28.6 5.2 16.1 25.9 22.8 16.0 4.0 1.1 64.3 0.5 46.0 44.7 43.2 0.9 6.4 0.9 10.2 3.4 75.5 10.9 45.3 3.3 GLRX5 "C14orf87, GRX5, PR01238" ENSG00000182512 "Glutaredoxin 5" Q86SX6 14 95533503-95544724 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 518.5;Erythroid cells: 1134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042465, HPA063716" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA042465: AB_10794048, HPA063716: AB_2685102" "unprognostic (2.57e-1)" "unprognostic (6.76e-2)" "unprognostic (1.60e-2)" "unprognostic (2.69e-2)" "unprognostic (3.72e-2)" "unprognostic (2.43e-3)" "unprognostic (1.29e-1)" "unprognostic (5.41e-2)" "unprognostic (8.28e-2)" "prognostic favorable (1.08e-5)" "unprognostic (1.85e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.83e-10)" "unprognostic (1.44e-1)" "unprognostic (3.81e-2)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" 37.2 52.1 44.1 17.6 44.9 178.8 27.2 43.8 50.2 22.3 46.7 44.8 46.2 19.2 39.0 24.5 23.6 17.5 76.9 46.6 45.8 74.5 105.5 18.3 23.1 43.3 44.5 32.8 31.5 46.3 18.9 37.8 44.3 26.8 37.3 10.1 29.3 29.6 195.0 18.3 33.2 24.4 42.9 20.8 34.2 35.7 46.2 40.3 26.7 168.9 27.0 24.5 15.0 42.9 77.1 92.7 61.4 68.0 74.2 57.5 202.0 54.9 56.1 69.4 69.1 124.8 87.5 111.7 77.4 42.8 39.2 75.5 116.5 79.6 71.5 68.5 94.4 100.3 63.4 202.2 73.5 160.9 96.5 55.4 74.1 49.9 81.1 28.1 76.1 94.4 115.7 88.3 61.2 205.5 133.6 165.9 81.5 89.7 107.8 220.8 184.3 67.8 93.3 89.3 127.9 75.2 54.8 81.3 87.7 59.9 107.7 72.6 55.6 30.5 65.0 77.6 85.7 41.7 57.9 92.0 67.2 99.8 72.2 0.4 2.9 4.8 3.4 4.3 4.9 4.6 4.6 6.0 4.7 5.4 3.7 3.9 1.3 3.9 2.7 9.0 6.2 1.8 44.1 44.9 43.8 50.2 46.6 45.8 43.3 44.5 44.3 42.9 46.2 42.9 78.7 28.9 30.0 7.8 41.1 108.5 58.7 7.5 61.5 38.5 112.8 135.9 150.0 64.3 10.4 95.6 33.3 97.8 66.5 76.3 518.5 15.2 312.0 49.7 61.5 58.9 54.0 1134.9 15.0 15.6 164.9 66.2 46.4 48.3 14.7 110.3 47.2 147.2 58.7 50.5 16.4 72.1 4.1 41.7 58.7 90.2 54.3 50.7 87.2 7.5 21.3 128.1 52.5 12.5 15.2 15.2 39.5 73.7 75.2 108.2 51.8 281.4 9.1 43.0 59.2 61.1 92.7 115.4 79.0 102.2 124.9 53.8 48.8 169.0 88.0 76.6 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182378098-182392206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1443.6" "Group enriched" "Detected in all" 4 "Late spermatids: 8544.2;Muller glia cells: 6247.0" "Cancer enhanced" "Detected in all" "liver cancer: 365.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 656.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 656.8" "Cell line enhanced" "Detected in many" "ASC diff: 1150.8;ASC TERT1: 807.6;HSkMC: 702.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported "Plasma membrane,Mitochondria,Cytosol" NA NA 150000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "CAB008636: AB_1616669, HPA007316: AB_888438, HPA007571: AB_1078980" "prognostic favorable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 753.5 76.0 694.3 156.9 746.5 232.9 573.5 717.5 1237.1 161.4 583.2 157.8 24.4 116.7 115.7 218.7 224.3 105.4 129.7 676.6 764.7 65.3 280.7 221.7 75.2 891.0 783.7 303.0 204.7 32.3 70.5 176.6 767.0 103.4 92.5 891.1 233.5 96.0 1443.6 231.4 148.2 124.1 725.0 216.4 648.2 87.1 811.4 97.0 257.4 472.0 103.2 185.5 292.0 810.4 26.4 10.8 117.2 0.2 1150.8 807.6 86.0 44.1 141.7 25.9 23.4 64.1 26.7 22.4 46.3 85.5 23.8 59.3 51.8 309.4 21.5 61.2 143.3 296.5 47.6 124.8 61.1 132.6 227.2 702.1 363.3 32.9 384.6 39.1 52.8 71.7 254.3 13.3 92.6 15.0 208.2 126.5 87.3 36.8 55.0 74.3 31.3 38.6 45.8 114.0 79.7 52.5 12.4 157.3 17.4 93.3 153.1 165.9 39.7 0.9 1.9 0.8 10.1 4.8 3.4 0.4 22.3 73.9 5.0 396.5 153.4 409.4 42.3 145.8 17.6 11.5 29.9 35.5 80.0 17.8 15.3 25.3 656.8 27.2 130.5 43.7 13.0 172.0 694.3 746.5 717.5 1237.1 676.6 764.7 891.0 783.7 767.0 725.0 811.4 810.4 127.8 125.0 173.8 599.4 37.6 134.7 533.8 1190.7 260.0 105.6 166.6 99.1 216.2 171.6 855.3 82.8 52.1 161.7 113.4 118.3 74.3 124.2 1491.3 140.2 150.0 191.5 325.9 319.7 3.4 116.6 65.9 404.4 388.4 124.6 786.3 88.0 152.8 597.1 798.0 43.7 22.0 256.7 451.6 907.2 614.1 8544.2 487.4 687.4 136.9 74.9 112.7 6247.0 42.2 38.2 330.0 108.1 105.3 375.0 38.7 421.0 10.3 46.6 569.9 176.0 92.1 481.5 218.5 48.2 63.6 186.5 128.3 235.3 108.6 53.3 173.3 1420.5 GLYATL1 "FLJ34646, MGC15397" ENSG00000166840 "Glycine-N-acyltransferase like 1" Q969I3 11 58905398-59043527 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 576.3" "Group enriched" "Detected in some" 4 "Hepatocytes: 234.3;Proximal tubular cells: 797.1" "Group enriched" "Detected in some" 8 "liver cancer: 14.1;prostate cancer: 13.3;renal cancer: 10.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.0;Daudi: 4.9;RPTEC TERT1: 1.5;U-2197: 1.2" HPA039501 Supported Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Cytosol "HPA039501: AB_2676545" "unprognostic (9.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.90e-5)" "unprognostic (3.93e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-1)" "prognostic favorable (3.69e-4)" "unprognostic (3.62e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.03e-5)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 1.3 0.3 0.4 0.1 0.4 0.3 1.6 0.1 0.7 0.1 1.3 0.9 0.0 0.1 0.3 141.4 576.3 0.0 0.1 0.9 0.2 0.0 1.7 2.6 0.0 0.0 1.1 11.1 0.3 0.2 1.9 0.0 0.0 0.6 0.2 0.0 0.3 0.1 2.7 0.1 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.1 0.5 0.4 2.0 0.0 4.9 0.0 0.3 0.4 0.0 0.0 0.0 0.8 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.0 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.3 0.9 0.2 1.1 0.3 0.3 0.3 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.3 12.8 0.0 14.7 0.0 0.0 0.0 0.1 107.6 0.1 0.0 2.5 0.1 0.5 0.0 8.0 0.7 0.6 0.0 0.1 0.0 0.1 0.0 0.1 5.0 234.3 0.0 0.0 0.8 0.1 0.0 8.1 0.0 0.0 0.0 3.1 1.8 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.0 1.3 0.0 797.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 1.9 0.1 0.9 0.2 GNA14 ENSG00000156049 "G protein subunit alpha 14" O95837 9 77423079-77648322 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 219.1;Early spermatids: 50.2;Hepatic stellate cells: 61.4;Late spermatids: 38.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 95 "basophil: 27.3" "Lineage enriched" "Detected in single" 95 "granulocytes: 27.3" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.3;HUVEC TERT2: 1.6;PC-3: 3.2;THP-1: 1.6;U-2197: 2.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA048886: AB_2680544" "unprognostic (7.80e-3)" "unprognostic (1.10e-2)" "unprognostic (1.09e-2)" "unprognostic (1.18e-3)" "unprognostic (2.03e-1)" "unprognostic (1.53e-4)" "unprognostic (2.48e-6)" "unprognostic (6.35e-3)" "unprognostic (3.34e-1)" "unprognostic (9.04e-2)" "unprognostic (1.21e-1)" "unprognostic (2.43e-1)" "unprognostic (2.92e-2)" "unprognostic (1.04e-3)" "unprognostic (1.79e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-1)" 3.4 2.2 7.3 4.0 6.5 0.0 2.4 2.7 8.4 3.6 11.8 5.8 1.7 15.6 5.2 4.8 3.6 4.9 4.1 9.2 4.5 11.7 6.0 8.8 3.3 9.7 5.0 6.0 1.4 1.4 3.1 7.0 7.0 6.8 6.1 0.1 8.0 13.7 0.6 0.9 3.0 13.8 8.1 7.3 3.3 2.1 5.6 0.7 17.6 0.6 2.1 7.6 4.8 13.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.3 1.0 0.3 0.0 0.6 0.0 0.9 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.4 3.2 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.8 0.4 0.0 1.2 0.3 1.6 0.4 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 27.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 7.3 6.5 2.7 8.4 9.2 4.5 9.7 5.0 7.0 8.1 5.6 13.9 2.3 0.0 1.1 219.1 0.2 0.6 2.0 0.2 0.0 0.0 1.0 0.4 0.8 0.0 6.5 0.0 0.0 0.1 0.0 2.6 0.0 0.7 50.2 1.7 4.9 12.8 3.0 2.7 15.8 1.0 0.1 4.2 0.0 1.8 4.5 0.1 61.4 1.2 0.3 0.0 4.4 13.7 2.0 2.5 1.1 38.8 3.7 0.2 1.8 15.9 0.0 0.0 0.0 7.1 12.4 0.1 2.7 1.9 0.0 1.0 0.5 7.1 20.8 0.0 0.0 19.4 0.9 0.4 0.7 0.3 0.6 0.1 0.2 0.5 2.9 4.9 GNA15 GNA16 ENSG00000060558 "G protein subunit alpha 15" P30679 19 3136033-3163749 "Plasma proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.6;esophagus: 108.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 141.5;Langerhans cells: 190.6;Macrophages: 78.3;Suprabasal keratinocytes: 95.8;Urothelial cells: 173.8" "Group enriched" "Detected in all" 4 "cervical cancer: 39.9;head and neck cancer: 46.4;lung cancer: 17.3;pancreatic cancer: 11.9;urothelial cancer: 31.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 67.1" "Group enriched" "Detected in many" 4 "dendritic cells: 67.1;granulocytes: 19.4;monocytes: 29.1" "Cell line enhanced" "Detected in some" "HBEC3-KT: 65.4;HMC-1: 152.1;MOLT-4: 162.4;NB-4: 59.8;REH: 119.3;THP-1: 62.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043113 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA043113: AB_10967343" "prognostic favorable (7.57e-5)" "unprognostic (6.06e-2)" "unprognostic (3.43e-1)" "prognostic favorable (2.01e-4)" "unprognostic (4.34e-2)" "unprognostic (2.09e-1)" "unprognostic (1.14e-2)" "unprognostic (5.38e-3)" "unprognostic (1.82e-1)" "unprognostic (3.22e-2)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (4.26e-6)" "unprognostic (1.04e-1)" "unprognostic (2.16e-3)" "unprognostic (2.36e-1)" "unprognostic (2.07e-1)" 6.8 3.1 4.0 12.4 3.8 75.6 4.6 4.0 7.3 13.3 4.7 2.5 1.7 1.3 0.4 108.8 2.4 4.6 1.9 4.1 4.1 2.0 1.4 13.1 4.2 5.4 4.5 0.8 1.2 0.4 1.4 7.6 5.1 11.6 1.8 0.1 19.5 2.5 0.6 50.8 2.5 3.1 4.9 8.8 4.3 1.4 6.6 32.0 1.2 0.9 12.1 28.1 41.6 6.4 44.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 18.7 0.1 0.1 0.0 0.1 36.2 0.0 65.4 0.0 0.1 0.0 19.1 0.1 0.0 0.0 27.2 152.1 0.0 40.0 0.2 26.2 0.0 0.0 16.6 0.1 0.3 0.0 0.0 162.4 59.8 0.1 2.9 0.0 119.3 0.0 0.2 0.0 23.6 0.2 0.0 4.6 0.2 0.2 0.0 0.0 62.1 0.1 0.0 0.2 0.2 0.3 0.2 0.0 0.1 0.3 29.8 0.1 19.4 29.1 14.3 0.0 21.8 1.1 0.0 2.0 0.3 28.8 0.0 0.0 0.0 6.9 4.4 15.5 67.1 8.7 13.3 4.0 3.8 4.0 7.3 4.1 4.1 5.4 4.5 5.1 4.9 6.6 6.4 1.0 9.6 8.8 0.0 2.2 67.2 141.5 65.5 9.1 0.2 7.4 3.7 0.5 0.0 39.0 3.7 0.0 0.5 27.6 0.5 0.0 0.7 0.5 1.4 0.5 3.1 6.6 21.0 1.3 0.0 0.8 2.5 3.6 3.9 34.3 0.0 0.7 0.0 66.5 0.0 0.4 2.2 57.0 36.2 190.6 0.8 0.0 78.3 21.4 7.5 32.0 0.0 0.0 0.0 0.2 13.2 0.3 0.0 3.6 69.3 0.0 0.1 21.7 0.1 19.7 0.3 3.3 4.0 2.0 38.0 95.8 0.4 19.6 0.1 1.4 173.8 GNAI3 87U6 ENSG00000065135 "G protein subunit alpha i3" P08754 1 109548615-109600195 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 350.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022099, HPA042141" Approved Approved Nucleoplasm,Nucleoli,Centrosome NA NA 1400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 41: Macrophages - Immune response" Centrosome "Nucleoplasm, Nucleoli" "CAB022099: , HPA042141: AB_2677870" "unprognostic (2.19e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.44e-2)" "unprognostic (2.59e-1)" "unprognostic (9.45e-3)" "prognostic unfavorable (5.30e-6)" "unprognostic (2.56e-3)" "unprognostic (2.18e-2)" "prognostic favorable (4.59e-4)" "unprognostic (1.83e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (7.27e-2)" "unprognostic (1.39e-1)" "unprognostic (1.25e-2)" "unprognostic (1.66e-2)" 12.7 8.2 5.8 14.2 6.1 27.7 11.9 7.3 7.5 10.9 8.6 11.8 10.4 12.1 8.0 21.8 8.0 11.3 4.2 6.0 6.5 11.2 15.3 9.7 14.1 6.7 5.9 8.8 9.3 8.9 1.8 14.8 6.8 10.3 11.8 17.8 7.7 9.0 3.8 18.4 10.6 13.6 6.3 11.4 9.0 8.7 6.2 14.2 8.0 5.5 15.9 15.5 4.0 7.3 48.3 16.4 31.0 17.3 28.4 35.0 25.7 35.3 28.6 36.0 35.5 24.4 16.1 25.3 22.4 37.6 21.6 24.5 30.0 35.3 49.4 29.2 18.0 22.1 26.3 21.9 25.1 34.9 18.8 25.2 30.4 41.3 27.8 24.2 42.8 19.1 29.8 24.2 35.5 32.9 27.3 28.4 31.3 23.0 19.1 19.2 73.6 16.6 37.4 35.4 19.5 34.9 24.7 27.6 39.4 22.8 21.1 30.5 36.7 29.4 40.7 44.9 39.2 25.6 30.2 29.2 47.6 34.4 47.1 32.4 29.7 57.8 21.1 44.3 22.4 20.1 20.4 20.6 31.9 17.1 16.8 19.4 53.8 19.9 44.6 14.2 23.8 36.3 5.8 6.1 7.3 7.5 6.0 6.5 6.7 5.9 6.8 6.3 6.2 7.3 104.0 44.8 31.5 17.0 76.6 151.2 104.3 92.2 63.2 29.9 67.7 45.3 14.3 37.1 61.0 58.8 350.3 80.3 98.8 63.9 64.6 97.9 14.7 65.5 71.5 82.6 84.3 43.8 37.5 101.7 153.7 69.2 55.5 110.9 46.3 50.1 56.7 57.2 107.9 25.2 36.4 72.3 59.0 115.0 106.9 9.4 48.7 127.4 74.7 31.9 102.4 47.9 45.3 35.7 31.3 101.6 58.9 47.4 66.3 72.5 48.9 53.5 51.7 26.2 52.6 59.0 77.6 68.6 54.7 82.1 188.4 106.9 94.3 51.7 63.5 143.0 GNAQ "G-ALPHA-q, GAQ" ENSG00000156052 "G protein subunit alpha q" P50148 9 77716097-78031811 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 556.6;Excitatory neurons: 405.6;Microglial cells: 394.4;Oligodendrocyte precursor cells: 338.3;Oligodendrocytes: 495.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 27.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 27.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010036, HPA048886" Uncertain Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA 800000 "Cluster 38: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB010036: AB_631536, HPA048886: AB_2680544" "unprognostic (2.10e-1)" "unprognostic (8.53e-2)" "unprognostic (1.45e-1)" "unprognostic (4.37e-2)" "unprognostic (1.87e-1)" "unprognostic (6.83e-3)" "unprognostic (1.05e-1)" "unprognostic (3.84e-2)" "unprognostic (2.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.11e-7)" "unprognostic (1.90e-1)" "unprognostic (3.13e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" 23.5 21.3 37.2 18.8 42.2 43.8 20.1 35.8 51.3 21.1 19.3 30.3 14.5 23.7 18.7 23.2 16.9 20.1 8.6 51.0 38.5 20.9 22.0 31.1 9.9 40.5 42.7 22.4 14.6 16.3 12.5 21.7 39.9 21.2 27.2 10.4 16.8 25.7 10.5 8.9 16.8 27.4 42.4 11.3 27.9 11.5 45.5 19.7 23.1 11.8 9.1 23.5 13.8 48.5 30.6 34.1 29.8 32.0 34.9 35.5 42.8 40.7 29.7 16.6 20.6 10.5 24.1 0.1 32.0 35.5 24.5 48.5 22.5 23.4 20.6 1.1 12.5 83.0 29.0 21.4 31.4 51.8 30.0 24.3 28.0 33.9 32.5 34.3 42.7 70.3 14.8 0.2 29.5 38.5 58.8 31.0 24.0 46.5 4.7 22.0 36.5 0.3 37.8 64.5 33.1 49.6 29.3 23.3 30.5 27.5 22.2 18.3 55.0 29.2 1.9 41.9 24.0 0.2 0.1 0.3 20.3 28.9 32.0 27.0 2.5 5.7 0.8 2.2 1.7 0.9 2.0 1.1 2.8 0.9 2.1 1.7 8.9 3.6 4.5 3.2 2.2 1.5 37.2 42.2 35.8 51.3 51.0 38.5 40.5 42.7 39.9 42.4 45.5 48.5 117.7 176.3 97.5 556.6 4.8 47.3 38.4 42.7 39.3 34.0 75.6 54.5 6.0 58.6 48.3 77.3 16.7 47.4 33.4 137.0 7.9 36.2 18.9 57.5 64.2 107.3 92.3 58.0 405.6 39.7 53.2 51.7 70.8 76.0 50.7 40.2 98.6 64.0 53.7 82.4 242.0 92.5 30.5 139.5 173.9 11.1 39.4 128.8 48.0 394.4 114.6 40.5 8.2 338.3 495.2 54.2 60.7 52.3 6.2 70.5 52.9 45.4 67.0 5.0 26.3 62.3 40.8 5.6 13.2 46.3 21.6 29.0 25.0 45.2 75.4 70.1 GNB4 ENSG00000114450 "G protein subunit beta 4" Q9HAV0 3 179396088-179451476 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 81.1;Kupffer cells: 98.1;Macrophages: 66.8;Microglial cells: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 143.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018383, CAB018737, HPA040736" Supported Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB018383: AB_631542, CAB018737: AB_640712, HPA040736: AB_2677106" "unprognostic (2.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (5.97e-3)" "unprognostic (2.12e-1)" "unprognostic (1.44e-2)" "unprognostic (8.28e-2)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (1.90e-3)" "unprognostic (3.13e-2)" "unprognostic (8.90e-2)" "unprognostic (2.80e-3)" 14.9 6.3 8.7 21.9 19.2 33.7 12.4 7.3 11.2 11.5 2.9 9.5 5.9 9.2 3.7 21.9 7.0 15.2 13.9 9.6 8.7 5.9 7.8 16.0 17.7 15.5 8.5 5.8 2.8 2.7 3.0 21.8 14.5 4.5 8.6 2.0 4.7 4.0 3.1 34.1 6.4 23.5 14.5 18.1 7.4 4.3 10.9 7.9 6.3 5.7 11.5 13.2 6.8 19.7 33.4 15.4 37.7 0.8 23.8 41.5 44.1 46.7 33.1 54.1 61.3 0.8 3.7 61.6 9.9 54.3 49.7 0.6 36.4 43.1 56.7 143.6 29.2 71.3 54.9 0.7 23.4 62.3 16.2 32.9 6.6 42.4 21.6 12.0 59.3 13.7 18.7 0.8 42.8 1.3 32.8 24.3 18.9 0.2 19.3 61.4 49.2 25.3 34.9 1.9 7.0 20.5 37.5 33.0 61.1 23.0 67.5 26.1 45.3 45.1 27.4 13.6 61.6 0.3 0.9 0.8 24.7 52.8 35.4 5.6 21.3 11.0 0.2 27.8 0.1 6.7 0.4 0.3 24.9 13.6 0.4 0.3 14.5 3.4 23.5 12.8 0.6 8.8 8.7 19.2 7.3 11.2 9.6 8.7 15.5 8.5 14.5 14.5 10.9 19.7 40.0 25.6 12.8 17.9 20.1 18.7 1.8 2.5 13.6 1.7 14.3 12.3 15.6 0.0 12.3 3.7 6.2 13.8 11.5 0.1 3.9 1.1 1.2 15.6 22.9 42.9 0.0 22.9 18.6 1.6 18.7 26.6 3.6 10.8 10.8 16.2 53.2 0.9 81.1 1.7 18.4 0.0 2.0 98.1 17.4 1.4 10.2 66.8 14.2 91.8 59.9 0.8 2.1 11.6 7.7 2.8 0.0 15.8 8.1 2.6 0.2 0.2 11.3 4.0 26.3 9.9 41.8 2.3 16.8 23.4 25.4 4.1 2.9 14.7 0.0 1.3 GNG12 ENSG00000172380 "G protein subunit gamma 12" Q9UBI6 1 67701475-67833467 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057790, HPA062208" Enhanced Supported Approved Mitochondria NA NA 550000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA057790: AB_2683527, HPA062208: AB_2684711" "unprognostic (5.18e-2)" "unprognostic (1.76e-3)" "unprognostic (4.46e-3)" "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (4.71e-2)" "unprognostic (5.29e-2)" "unprognostic (5.84e-3)" "unprognostic (5.50e-2)" "unprognostic (3.41e-2)" "unprognostic (4.46e-3)" "unprognostic (8.13e-2)" "unprognostic (4.12e-3)" "unprognostic (2.33e-2)" "unprognostic (9.33e-2)" "unprognostic (7.78e-2)" "unprognostic (2.14e-3)" 63.4 57.0 14.4 28.5 12.3 0.3 50.1 10.4 14.0 59.3 13.5 68.4 122.0 59.7 27.7 82.0 43.4 59.3 34.5 13.7 19.5 79.2 44.8 34.3 12.0 21.9 29.1 47.9 25.2 54.7 13.1 60.2 16.9 38.3 65.7 6.6 26.6 47.6 12.9 80.4 110.8 73.9 18.6 56.2 42.7 17.7 16.4 15.9 59.8 19.7 22.7 56.5 46.5 18.7 60.5 55.5 58.0 31.5 241.2 207.9 59.5 182.9 237.2 157.9 141.0 26.5 58.2 0.1 75.9 258.0 98.8 44.2 36.6 150.0 275.7 0.5 28.1 1.0 46.0 0.1 96.0 0.1 3.0 125.7 87.8 168.7 221.8 221.1 251.9 0.0 3.6 0.3 175.6 10.2 0.1 0.5 44.1 65.7 68.3 0.3 119.6 0.9 151.8 53.5 13.2 26.8 126.8 52.1 248.4 48.8 26.9 1.1 326.7 182.5 118.8 332.0 114.5 3.0 0.3 0.5 115.3 7.1 252.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 12.3 10.4 14.0 13.7 19.5 21.9 29.1 16.9 18.6 16.4 18.7 49.7 54.5 32.2 54.5 2.1 201.3 78.8 53.3 78.6 2.1 52.4 37.1 26.7 35.8 42.8 58.8 6.2 61.8 0.9 243.1 74.3 96.2 14.6 51.8 20.6 67.0 34.7 5.3 0.5 138.5 105.6 82.6 45.3 49.3 3.8 21.3 76.1 45.6 27.9 3.3 15.3 56.3 30.5 18.2 32.4 16.6 71.4 6.2 78.2 21.5 3.6 3.0 0.0 63.3 1.3 143.7 99.9 75.6 0.2 119.9 227.3 177.9 79.2 18.9 52.6 54.8 71.7 1.8 18.8 83.1 216.8 175.9 4.5 107.1 61.8 109.1 GOLM2 "CASC4, DKFZp459F1927, H63" ENSG00000166734 "Golgi membrane protein 2" Q6P4E1 15 44288719-44415758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 19.9;Cardiomyocytes: 24.0;Cytotrophoblasts: 16.3;dendritic cells: 16.1;Extravillous trophoblasts: 19.4;Fibroblasts: 18.2;Hofbauer cells: 27.3;Syncytiotrophoblasts: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043015, HPA049488" Enhanced Enhanced "Golgi apparatus" NA NA 1200000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA043015: AB_2678271, HPA049488: AB_2680790" "unprognostic (2.64e-2)" "unprognostic (2.63e-1)" "unprognostic (3.38e-1)" "unprognostic (1.81e-2)" "unprognostic (8.08e-2)" "unprognostic (1.35e-1)" "unprognostic (1.20e-2)" "unprognostic (2.20e-1)" "unprognostic (2.40e-1)" "unprognostic (1.68e-2)" "unprognostic (4.99e-2)" "unprognostic (2.60e-2)" "prognostic favorable (1.45e-5)" "unprognostic (2.15e-1)" "unprognostic (3.56e-2)" "unprognostic (9.65e-2)" "unprognostic (1.12e-1)" 39.5 84.5 48.5 32.4 47.0 16.5 43.2 43.1 59.2 57.9 62.4 45.7 28.8 50.4 53.5 23.7 53.8 50.5 33.1 42.8 52.6 54.0 60.9 40.9 30.8 49.6 51.5 55.3 37.4 82.0 38.7 34.4 46.9 67.5 43.8 33.7 47.8 56.1 22.3 13.2 29.8 44.4 46.7 35.4 49.4 34.6 52.9 28.9 84.6 26.3 29.5 39.2 24.3 52.7 45.0 38.7 51.9 92.6 141.4 121.8 32.0 78.6 125.2 44.9 57.1 19.3 80.0 13.5 106.4 119.3 47.8 53.8 34.4 25.5 48.2 64.6 19.5 21.4 41.8 35.9 65.1 42.5 68.1 72.1 28.3 49.8 38.4 126.8 53.4 34.2 33.0 103.4 56.2 23.2 36.7 33.2 14.8 60.8 27.5 30.5 29.3 43.3 58.8 54.4 23.3 53.2 60.7 57.0 26.6 28.1 64.1 49.2 76.4 78.1 39.8 112.5 69.5 79.0 145.1 27.9 92.6 58.5 51.7 20.9 14.7 20.8 15.2 9.8 16.3 11.9 12.4 15.2 12.0 10.7 9.5 9.9 37.8 10.5 18.2 10.6 13.2 13.6 48.5 47.0 43.1 59.2 42.8 52.6 49.6 51.5 46.9 46.7 52.9 52.7 19.9 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 16.3 16.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 19.4 18.2 0.0 0.0 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 12.7 2.9 0.0 0.0 0.0 GOLT1A "CGI-141, FLJ42654, GOT1, MGC62027, YMR292W" ENSG00000174567 "Golgi transport 1A" Q6ZVE7 1 204198163-204213988 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 190.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 131.3;Proximal enterocytes: 206.8" "Cancer enriched" "Detected in many" 6 "liver cancer: 80.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 18.0;CAPAN-2: 20.0;Hep G2: 25.9;MCF7: 43.5;OE19: 16.1;RT4: 27.7;SK-BR-3: 27.2" "Region enhanced" "Detected in many" "cerebral cortex: 9.0" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.43e-1)" "unprognostic (1.13e-1)" "unprognostic (2.22e-3)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (6.20e-3)" "unprognostic (2.14e-1)" "unprognostic (8.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.26e-2)" "unprognostic (7.33e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.35e-5)" "unprognostic (1.37e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-3)" "prognostic favorable (1.51e-4)" 0.3 0.1 6.1 0.4 9.2 0.0 5.3 7.0 5.3 10.9 3.9 5.6 47.4 0.3 10.7 0.5 3.3 1.6 0.1 4.3 11.2 16.2 190.7 8.3 0.1 4.7 5.3 0.1 22.3 18.3 30.4 3.5 4.7 5.3 5.0 1.5 3.4 2.1 0.3 0.5 45.5 0.3 4.5 0.1 8.2 2.6 11.6 0.8 0.7 0.0 0.2 13.1 0.4 2.8 0.5 8.2 0.0 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 18.0 20.0 0.0 0.7 0.2 0.0 0.6 0.0 0.1 0.1 0.0 0.3 0.1 0.0 25.9 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 43.5 0.0 0.1 4.0 16.1 0.2 0.0 0.1 0.4 8.5 27.7 1.3 1.8 0.8 27.2 0.1 0.7 8.9 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 6.1 9.2 7.0 5.3 4.3 11.2 4.7 5.3 4.7 4.5 11.6 2.8 0.1 0.0 19.5 0.3 0.1 0.0 12.7 2.6 2.8 1.7 7.2 4.7 0.2 40.0 5.1 16.5 0.0 13.3 0.1 7.0 13.7 29.2 0.9 0.5 0.1 0.3 10.3 0.0 2.2 19.1 0.5 1.1 8.2 2.0 1.3 1.4 1.8 131.3 1.3 1.7 0.7 7.8 2.0 1.6 0.0 0.4 0.0 0.2 1.8 0.0 0.0 0.0 0.0 4.5 0.1 18.7 5.6 0.0 0.0 15.0 206.8 14.7 0.3 0.2 0.0 0.3 0.3 2.9 0.9 1.4 0.1 26.4 0.5 0.2 12.5 20.5 GOT1 AST1 ENSG00000120053 "Glutamic-oxaloacetic transaminase 1" P17174 10 99396870-99430624 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 511.1;liver: 369.5;skeletal muscle: 489.9;tongue: 1011.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 449.0;Distal tubular cells: 240.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064532, HPA072629" Enhanced Supported Nucleoplasm,Cytosol NA Yes 100000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA064532: AB_2685279, HPA072629: AB_2686540" "unprognostic (6.40e-2)" "prognostic favorable (6.23e-4)" "unprognostic (5.99e-2)" "unprognostic (2.84e-2)" "unprognostic (2.82e-1)" "unprognostic (2.96e-2)" "unprognostic (5.25e-2)" "unprognostic (1.08e-3)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (1.79e-1)" "prognostic favorable (3.72e-13)" "unprognostic (1.93e-2)" "unprognostic (4.23e-1)" "unprognostic (6.85e-2)" "unprognostic (1.00e-1)" 14.7 54.9 67.8 14.7 71.1 8.0 22.7 70.3 119.1 53.1 82.6 50.9 62.0 13.1 25.9 42.7 17.9 49.0 511.1 70.0 77.6 143.1 369.5 15.5 14.1 83.5 55.0 18.1 34.0 142.4 22.5 14.4 83.7 22.7 59.2 106.2 48.6 27.4 489.9 23.9 45.8 21.4 48.4 16.9 58.9 33.6 69.1 17.7 47.7 1011.6 30.3 22.3 21.0 70.1 73.7 40.3 46.0 114.4 35.1 30.7 127.1 58.9 108.7 101.8 109.8 89.9 56.4 71.9 20.4 50.2 89.2 88.6 107.1 78.9 105.8 25.7 46.7 28.1 46.7 114.3 184.9 77.9 44.0 47.3 82.5 86.9 228.4 69.5 49.5 48.6 71.1 106.2 65.4 64.9 42.5 56.5 29.2 118.7 56.1 45.5 44.4 72.8 173.7 37.5 19.6 28.7 44.8 59.3 222.6 66.8 115.7 27.1 23.3 25.4 56.3 28.0 68.7 76.8 99.7 74.3 65.4 40.8 34.1 4.0 8.7 6.8 19.7 25.8 18.4 17.6 21.5 20.7 21.9 21.2 15.6 22.7 0.8 20.5 31.5 36.4 27.6 15.6 67.8 71.1 70.3 119.1 70.0 77.6 83.5 55.0 83.7 48.4 69.1 70.1 10.3 16.0 16.2 26.1 38.8 11.9 41.8 82.7 24.5 95.6 18.8 21.2 449.0 72.9 34.4 73.5 62.6 35.9 10.7 62.1 240.7 51.9 166.7 17.8 9.3 16.7 19.7 39.5 47.4 30.8 18.1 23.5 76.9 21.5 31.8 20.2 17.2 191.8 31.6 75.7 63.3 45.3 54.9 12.4 6.9 24.1 11.1 13.0 49.8 13.1 10.5 36.6 6.2 21.1 37.2 27.6 34.4 14.3 22.4 13.1 97.0 163.3 27.9 76.5 13.1 15.2 20.5 116.7 10.4 40.9 10.4 55.1 14.6 47.0 66.4 42.3 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 305.7;liver: 144.1" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Hepatocytes: 184.5;Horizontal cells: 45.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 250.3;Hep G2: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA046339: AB_2679627, HPA060090: AB_2684202" "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favorable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 305.7 33.9 14.9 4.8 17.1 3.4 67.7 12.2 14.0 3.0 6.9 6.4 4.0 4.2 75.1 2.9 3.1 6.0 12.3 12.4 13.0 4.4 144.1 4.1 4.6 12.9 16.0 5.3 5.0 4.3 2.1 3.0 12.1 3.9 4.7 5.1 17.2 5.3 8.3 3.2 6.1 4.9 11.5 2.9 4.9 5.6 15.7 3.6 12.4 8.8 4.3 4.8 2.6 10.5 9.9 7.4 9.7 12.9 250.3 9.1 12.7 9.2 10.5 6.6 5.1 17.3 5.7 6.9 5.0 6.5 6.1 12.3 15.5 7.9 12.3 5.0 8.4 6.4 7.9 71.8 7.7 11.2 3.4 43.8 13.1 11.7 23.6 49.7 5.8 9.7 8.5 6.1 7.7 5.6 9.6 8.8 8.1 5.6 10.1 9.7 25.4 5.1 4.3 6.8 4.1 12.1 12.8 6.1 14.5 8.9 6.3 4.0 4.4 7.5 4.6 9.4 14.8 6.1 7.3 14.3 8.8 9.8 5.8 0.0 0.3 0.1 0.7 0.4 0.9 0.5 0.5 0.5 0.4 1.1 0.5 0.9 0.0 0.3 0.3 0.6 0.6 0.3 14.9 17.1 12.2 14.0 12.4 13.0 12.9 16.0 12.1 11.5 15.7 10.5 9.1 9.6 27.1 90.8 5.2 0.4 0.8 1.6 4.6 5.3 8.1 8.4 18.9 20.0 4.3 5.5 10.4 5.2 4.3 1.7 1.9 2.7 0.5 5.1 10.0 5.0 1.2 12.2 8.2 3.3 2.9 5.1 3.6 4.2 2.5 12.7 6.4 184.5 3.1 45.4 9.4 3.0 0.0 9.3 1.0 0.9 5.3 1.9 1.8 10.3 1.4 6.1 3.1 10.1 10.1 3.4 2.7 12.0 6.4 1.1 3.7 3.3 4.7 9.1 6.6 4.3 6.6 4.0 3.2 5.4 0.1 1.9 3.3 8.6 5.0 0.6 GPBP1L1 SP192 ENSG00000159592 "GC-rich promoter binding protein 1 like 1" Q9HC44 1 45627304-45688113 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028593 Approved Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028593: AB_10602906" "unprognostic (1.39e-1)" "unprognostic (8.41e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (6.35e-2)" "unprognostic (1.97e-3)" "unprognostic (2.42e-3)" "unprognostic (9.79e-2)" "unprognostic (3.91e-2)" "unprognostic (1.94e-3)" "unprognostic (1.12e-2)" "unprognostic (4.11e-1)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (4.51e-1)" "unprognostic (7.56e-3)" "unprognostic (6.13e-2)" 28.7 26.7 25.2 31.0 29.4 49.3 40.9 27.3 28.0 35.0 26.1 57.3 54.0 35.6 37.6 45.0 36.2 30.3 41.7 23.6 27.1 47.0 66.3 39.2 39.9 27.7 28.3 30.6 39.3 41.7 25.5 34.1 28.2 35.8 61.2 27.4 42.4 36.1 46.2 47.2 56.7 36.3 26.8 36.9 42.6 57.9 27.4 54.7 48.7 54.9 49.5 35.6 36.7 32.8 41.1 24.7 42.1 44.9 48.4 47.1 57.5 31.9 52.2 44.8 56.1 25.2 44.8 56.3 40.5 43.7 46.9 42.0 46.6 47.8 56.3 64.4 33.4 73.7 28.9 39.2 66.7 74.2 65.1 34.6 102.0 35.3 99.4 60.2 57.7 71.0 63.7 48.7 51.6 22.0 66.2 65.8 60.4 54.8 27.7 43.0 55.1 41.9 51.5 40.2 51.9 34.7 52.6 76.6 83.5 81.6 35.1 86.2 49.8 32.0 33.6 35.2 48.9 47.2 46.9 41.3 34.0 60.6 34.5 24.0 21.6 40.3 21.6 27.3 22.9 16.5 20.9 21.1 23.0 14.1 22.6 22.4 22.6 26.6 30.6 13.1 26.4 21.1 25.2 29.4 27.3 28.0 23.6 27.1 27.7 28.3 28.2 26.8 27.4 32.8 43.3 60.9 24.4 54.5 45.1 64.9 41.2 28.3 59.2 23.5 51.3 33.5 46.9 41.5 34.3 60.7 35.5 26.2 47.5 96.8 50.9 33.0 23.4 38.1 32.2 38.6 38.3 62.1 48.5 38.9 33.7 25.4 44.9 47.5 59.6 24.3 37.5 81.3 25.0 37.0 49.0 67.2 32.6 49.9 51.6 17.6 20.5 46.1 23.2 70.3 41.3 18.2 45.3 50.8 93.8 51.2 57.0 21.4 36.6 62.8 75.5 58.7 33.0 32.9 19.7 22.4 42.0 78.9 75.3 71.7 67.8 45.4 47.1 27.7 68.6 78.2 GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 226.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 199.8;Syncytiotrophoblasts: 102.7;Urothelial cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 9500000 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" 36.8 78.5 42.8 9.0 37.0 0.4 30.7 25.3 64.4 44.5 3.1 36.7 5.8 37.1 9.3 88.4 30.8 8.5 145.2 41.7 28.5 47.6 35.7 21.9 1.4 29.2 30.4 45.1 25.8 9.8 55.7 29.0 26.3 67.8 3.5 5.0 35.2 22.5 134.2 226.0 17.4 16.4 11.3 15.6 23.0 48.7 46.0 9.1 15.7 35.3 6.6 35.1 62.3 24.8 69.0 92.9 21.6 56.7 64.3 61.5 87.3 161.5 78.8 18.3 21.2 33.3 74.9 1.8 21.8 172.0 100.1 186.0 11.7 114.7 3.8 33.3 9.8 0.1 80.7 41.7 92.2 1.6 6.2 54.3 73.4 41.2 21.3 38.1 9.7 3.4 0.4 3.3 47.5 36.0 1.3 0.6 33.7 7.7 20.5 12.3 98.2 16.1 15.0 109.6 21.5 14.4 105.7 91.9 10.1 19.3 29.1 7.0 45.6 97.3 162.3 46.9 67.8 0.7 0.4 0.8 69.4 1.7 111.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.8 37.0 25.3 64.4 41.7 28.5 29.2 30.4 26.3 11.3 46.0 24.8 1.2 16.0 6.1 45.7 0.7 45.9 69.6 62.2 56.3 22.4 8.3 18.2 53.2 21.5 34.0 25.8 2.1 73.7 0.3 3.7 7.9 27.8 0.9 6.2 24.7 2.8 0.0 0.0 53.0 10.8 199.8 21.0 1.5 8.9 4.5 49.4 11.0 26.3 9.1 25.2 45.0 7.0 16.2 0.6 7.7 3.8 19.0 1.2 35.6 5.6 1.6 24.9 1.0 18.6 8.9 17.6 0.9 7.5 0.9 67.0 0.5 2.3 30.2 6.4 26.3 33.9 38.2 2.2 9.9 44.8 46.2 102.7 1.9 14.5 3.6 110.5 GPKOW "GPATC5, GPATCH5, Mos2, Spp2, T54" ENSG00000068394 "G-patch domain and KOW motifs" Q92917 X 49113407-49123735 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000287, HPA001894" Enhanced Enhanced Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA000287: AB_1079015, HPA001894: AB_1079014" "unprognostic (3.34e-2)" "unprognostic (9.54e-3)" "unprognostic (8.95e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (2.03e-3)" "unprognostic (1.02e-1)" "unprognostic (9.29e-2)" "unprognostic (7.96e-2)" "unprognostic (4.32e-1)" "unprognostic (7.08e-2)" "unprognostic (1.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.73e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-2)" 17.6 15.9 21.5 11.7 22.6 16.1 16.4 22.7 21.8 14.7 14.0 17.0 14.3 16.9 11.8 14.7 15.1 10.3 18.6 19.8 21.2 15.5 14.5 13.8 14.9 24.2 23.6 13.6 12.1 19.0 17.2 13.8 23.9 12.7 12.6 11.9 13.8 16.5 34.8 20.4 14.1 13.8 22.4 15.4 15.5 7.2 25.2 17.7 13.4 25.4 14.4 16.2 14.2 24.4 36.5 38.1 24.9 20.9 21.6 18.6 27.0 23.1 25.9 36.0 38.0 27.9 35.5 15.2 17.4 28.6 36.8 25.2 27.9 27.3 23.4 32.2 29.8 15.8 31.4 19.9 25.8 18.9 32.1 20.4 34.3 28.8 29.2 21.1 27.4 30.0 19.8 23.1 23.8 59.5 26.0 31.5 17.6 19.5 30.0 32.2 27.4 41.5 18.5 45.8 20.8 24.1 26.9 25.2 25.4 26.1 48.5 24.5 30.7 20.7 31.2 30.4 22.1 35.4 26.1 20.7 26.7 31.1 32.7 26.2 22.3 28.9 37.2 31.4 30.3 20.5 28.6 27.8 22.6 34.8 24.3 22.4 17.3 25.0 35.9 20.8 31.1 20.2 21.5 22.6 22.7 21.8 19.8 21.2 24.2 23.6 23.9 22.4 25.2 24.4 10.9 19.2 11.0 7.2 10.5 8.0 14.1 21.8 4.6 14.8 6.4 5.5 13.1 21.5 19.1 7.3 4.2 28.4 16.3 16.2 15.6 26.2 1.1 15.6 10.0 13.4 7.8 22.5 2.8 25.2 20.5 11.7 14.3 10.6 11.4 10.4 11.7 14.5 16.7 5.0 2.8 12.1 18.3 10.9 9.3 1.7 15.5 8.7 5.4 2.8 13.2 20.9 28.8 2.0 3.9 25.6 23.2 15.1 9.4 9.4 19.5 20.5 12.7 13.4 39.5 12.9 13.0 9.9 18.4 6.1 9.9 43.8 16.7 10.6 11.0 12.8 GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079543-168137667 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 41.5;smooth muscle: 27.6" "Cell type enriched" "Detected in many" 8 "Horizontal cells: 158.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 44.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Uncertain Nucleoplasm,Nucleoli Yes No "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Nucleoli "HPA015576: AB_1849283, HPA072047: AB_2686484" "unprognostic (1.45e-1)" "unprognostic (3.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (6.84e-2)" "unprognostic (3.24e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.04e-2)" "unprognostic (5.45e-2)" "unprognostic (1.31e-2)" "unprognostic (5.57e-6)" "unprognostic (3.93e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" 3.5 1.1 3.8 5.3 2.8 0.2 2.7 3.3 4.0 6.7 1.1 8.4 1.5 41.5 3.6 9.8 10.7 5.6 3.1 3.8 2.4 1.4 0.4 4.2 0.9 3.7 9.4 7.3 11.7 5.4 1.7 2.2 3.8 9.5 3.2 2.1 1.8 11.8 1.0 2.1 3.3 27.6 2.8 2.0 2.9 1.7 4.1 2.0 1.7 1.9 1.3 4.6 5.4 2.7 11.7 7.1 28.0 18.1 6.6 11.7 0.0 11.1 11.9 9.2 9.7 44.9 1.8 0.0 6.0 16.6 17.2 33.9 6.9 10.7 5.3 4.4 8.8 4.2 5.8 0.1 2.8 1.2 2.8 4.2 6.9 7.9 12.7 21.3 18.7 3.6 3.9 0.1 14.2 1.0 1.3 0.2 11.5 19.4 11.0 3.4 12.1 0.0 4.9 3.1 5.7 24.6 12.0 0.4 32.2 10.6 6.3 1.4 25.4 18.9 9.7 25.6 12.7 0.0 0.0 0.0 5.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 2.8 3.3 4.0 3.8 2.4 3.7 9.4 3.8 2.8 4.1 2.7 5.8 3.2 1.1 13.7 0.1 2.2 5.7 2.5 5.2 2.2 2.2 4.2 3.6 0.0 1.4 0.0 0.0 0.5 0.0 2.8 0.0 4.1 0.4 1.3 19.4 9.1 0.0 0.0 10.8 8.0 0.4 12.3 1.1 1.8 0.0 15.3 8.9 0.1 0.8 158.2 10.9 1.5 0.0 2.5 6.3 0.9 7.5 2.0 1.8 3.7 1.1 3.2 0.0 9.5 0.4 2.6 2.4 17.0 0.0 10.9 0.0 0.1 1.1 2.1 19.7 8.8 15.1 0.3 3.3 2.7 1.4 0.4 1.0 0.7 2.5 2.7 GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.6" "Cell type enhanced" "Detected in some" "Adipocytes: 26.7;Endothelial cells: 26.4;Hepatic stellate cells: 24.7;Sertoli cells: 6.6;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HUVEC TERT2: 18.7;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" 40.6 6.9 7.0 3.3 6.2 0.5 22.1 6.0 8.8 4.9 6.2 4.2 0.9 7.4 0.7 2.6 6.0 3.3 23.8 5.6 5.9 24.6 3.6 28.6 0.9 8.0 7.5 3.5 3.7 1.4 5.9 4.0 8.6 5.8 0.7 0.9 2.9 0.9 5.7 2.9 5.1 2.5 6.5 4.1 5.6 1.7 10.7 0.5 18.2 2.5 0.6 7.0 4.9 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.7 0.7 1.1 0.0 0.1 0.0 2.0 0.1 0.0 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.8 0.0 0.0 0.3 0.3 0.0 18.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 31.3 0.1 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 6.2 6.0 8.8 5.6 5.9 8.0 7.5 8.6 6.5 10.7 6.3 26.7 0.0 0.5 0.7 0.1 2.4 0.2 0.0 1.2 0.1 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.1 0.3 26.4 0.0 0.0 0.1 0.0 0.0 1.5 2.0 0.2 0.0 0.0 24.7 0.1 0.3 0.0 0.2 0.0 0.0 1.2 1.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 6.6 0.6 16.8 0.0 0.2 0.1 1.3 0.0 0.1 0.3 0.0 0.3 GPR55 ENSG00000135898 "G protein-coupled receptor 55" Q9Y2T6 2 230907318-230961066 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;lymphoid tissue: 4.4;testis: 4.7" "Cell type enhanced" "Detected in some" "B-cells: 2.1;Enteroendocrine cells: 1.8;Excitatory neurons: 2.3;Langerhans cells: 3.1;Plasma cells: 2.4;T-cells: 4.2" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 4 "basal ganglia: 4.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "Karpas-707: 32.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.88e-4)" "unprognostic (2.60e-2)" "unprognostic (2.27e-1)" "unprognostic (4.24e-3)" "unprognostic (5.93e-2)" "unprognostic (1.12e-4)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (4.37e-2)" "unprognostic (3.18e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-2)" "unprognostic (4.26e-1)" 0.2 0.0 0.3 1.8 4.6 0.2 0.5 0.0 0.5 0.1 0.0 0.8 1.3 0.1 0.0 0.5 0.1 0.5 0.1 0.3 0.4 0.0 0.2 0.5 2.9 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 1.0 0.2 0.0 0.4 2.2 0.1 0.0 4.1 0.7 4.7 1.0 1.9 0.1 0.0 4.4 0.9 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 2.1 0.0 0.6 0.0 0.0 0.0 0.0 6.5 0.0 0.2 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.8 32.0 0.0 0.0 0.2 0.9 0.7 0.0 1.0 0.1 0.0 3.1 0.0 0.0 1.2 0.0 0.0 0.0 6.0 0.0 0.0 2.3 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.1 1.9 0.1 0.9 0.2 0.9 0.1 0.7 1.3 1.7 0.3 4.6 0.0 0.5 0.3 0.4 0.1 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.3 2.1 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.8 0.0 0.0 0.1 1.8 0.0 2.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.4 0.0 0.1 0.0 0.1 1.4 0.0 0.3 3.1 0.9 0.0 1.2 0.0 1.0 0.9 0.0 1.0 0.5 0.1 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.2 0.1 0.2 0.1 GPRASP1 "GASP, GASP1" ENSG00000198932 "G protein-coupled receptor associated sorting protein 1" Q5JY77 X 102651092-102659083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 42.6;Cardiomyocytes: 28.6;Cone photoreceptor cells: 37.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 4.5;REH: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000161, HPA031061" Approved Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA000161: AB_2247872, HPA031061: AB_2673718" "unprognostic (3.92e-3)" "unprognostic (1.10e-1)" "unprognostic (2.07e-4)" "unprognostic (1.42e-1)" "unprognostic (3.32e-2)" "unprognostic (1.71e-3)" "unprognostic (3.57e-1)" "unprognostic (2.33e-2)" "unprognostic (1.58e-1)" "unprognostic (2.82e-1)" "prognostic favorable (1.77e-5)" "unprognostic (3.34e-1)" "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.23e-2)" 8.6 22.6 25.1 5.4 23.9 3.8 9.9 19.8 31.2 32.4 2.7 23.3 2.4 25.5 10.7 4.4 26.7 7.6 17.7 22.8 33.2 10.3 2.9 7.2 9.4 16.6 17.8 53.4 5.6 17.3 43.5 2.9 18.6 20.4 4.5 29.9 8.7 17.7 6.1 5.2 12.4 15.3 12.8 11.3 9.6 5.3 23.6 6.8 26.1 4.2 7.6 18.6 16.9 20.2 0.2 0.5 1.7 1.1 1.7 1.7 1.0 1.8 0.1 2.7 4.5 0.2 0.3 0.0 0.4 3.8 0.3 0.5 0.5 0.1 3.9 0.0 0.2 0.1 0.6 0.5 1.4 0.2 0.2 2.2 0.7 3.3 0.3 0.4 0.2 1.8 0.3 0.1 4.3 0.4 3.7 0.1 1.2 0.3 0.6 5.6 1.7 0.0 0.2 0.4 1.7 2.7 0.6 0.2 0.5 1.4 0.2 0.9 0.5 0.8 1.0 0.5 0.3 0.3 0.5 0.0 0.4 0.2 1.1 0.0 0.0 0.0 0.5 0.0 1.3 0.2 1.1 0.4 0.0 0.7 2.3 2.3 0.0 0.1 0.0 0.3 0.8 0.5 25.1 23.9 19.8 31.2 22.8 33.2 16.6 17.8 18.6 12.8 23.6 20.2 5.1 0.0 3.6 0.0 4.4 3.6 4.1 0.8 1.8 42.6 1.8 3.0 28.6 1.5 3.5 5.5 37.5 0.4 3.5 0.1 0.0 0.2 0.3 0.6 6.5 7.3 6.0 0.4 0.0 0.2 0.2 9.9 1.1 0.7 2.5 13.9 7.1 0.7 0.3 6.7 0.0 0.7 0.0 0.3 2.0 1.7 15.2 1.3 1.8 0.0 0.5 12.9 3.1 0.0 0.0 0.6 0.1 15.4 2.2 3.8 0.4 1.7 1.2 18.8 6.6 16.9 8.5 7.0 2.4 0.4 0.9 0.1 7.3 6.5 0.8 1.6 GPSM3 "AGS4, C6orf9, G18, G18.1a, G18.1b, G18.2, NG1" ENSG00000213654 "G protein signaling modulator 3" Q9Y4H4 6 32190766-32195523 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 160.8;lymphoid tissue: 229.3" "Cell type enhanced" "Detected in many" "B-cells: 261.0;dendritic cells: 238.9;Hofbauer cells: 278.3;Kupffer cells: 397.2;Langerhans cells: 209.3;Macrophages: 268.2;monocytes: 375.1;NK-cells: 352.2;T-cells: 256.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 226.9;NB-4: 115.8;THP-1: 107.1;U-937: 76.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 73000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.93e-2)" "unprognostic (2.51e-2)" "unprognostic (2.02e-2)" "prognostic favorable (5.98e-4)" "unprognostic (3.55e-1)" "unprognostic (3.07e-2)" "unprognostic (3.66e-1)" "unprognostic (6.61e-2)" "unprognostic (4.48e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (6.92e-9)" "unprognostic (2.01e-2)" "unprognostic (1.69e-2)" "unprognostic (5.47e-2)" "unprognostic (5.87e-2)" 28.7 11.8 11.1 96.8 10.3 160.8 15.5 10.8 14.1 8.9 10.5 17.9 14.4 6.8 9.1 9.4 13.9 24.8 14.9 10.5 13.4 15.9 14.5 62.9 139.9 15.6 13.6 5.3 6.1 1.8 7.6 22.2 13.9 13.8 15.8 0.3 11.8 5.5 3.7 9.1 67.7 10.0 12.3 229.3 17.5 5.6 14.6 83.0 11.6 5.6 100.8 32.8 9.1 14.4 1.0 0.0 1.6 0.6 0.1 0.2 1.5 1.3 17.0 5.6 8.8 0.2 5.2 41.1 7.8 6.7 0.5 0.9 0.1 7.2 3.1 53.8 0.1 59.5 0.0 1.2 9.6 0.0 226.9 2.0 0.0 1.9 5.9 1.2 25.8 25.7 11.4 47.9 1.6 0.0 23.6 115.8 0.0 0.0 0.5 24.5 0.0 38.4 1.4 0.0 0.6 0.1 0.0 0.6 8.7 2.1 1.1 107.1 22.6 3.0 3.1 0.0 1.5 1.1 0.9 25.9 0.9 76.3 15.5 44.1 55.8 194.3 35.5 73.3 35.7 52.8 45.5 44.7 57.9 41.9 38.5 42.7 244.9 27.1 71.5 24.3 34.7 53.2 11.1 10.3 10.8 14.1 10.5 13.4 15.6 13.6 13.9 12.3 14.6 14.4 12.8 0.0 2.2 1.0 261.0 11.2 12.9 11.5 4.0 0.2 7.7 9.1 0.5 2.8 7.3 3.7 0.0 3.4 238.9 2.2 0.0 7.9 6.5 1.1 1.0 19.5 1.2 46.3 0.1 5.2 5.1 7.1 8.6 0.9 57.8 0.5 28.2 4.4 278.3 0.0 0.3 6.5 30.5 397.2 209.3 12.1 1.2 268.2 44.4 4.7 375.1 0.5 352.2 0.0 0.3 20.5 34.2 0.0 76.4 5.8 0.5 2.4 5.5 0.5 6.6 1.3 9.4 0.8 3.9 1.4 8.5 6.3 256.1 7.8 3.7 24.6 GPX7 "FLJ14777, GPX6, NPGPx" ENSG00000116157 "Glutathione peroxidase 7" Q96SL4 1 52602371-52609051 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 68.6;HEL: 63.9;REH: 76.4;RPMI-8226: 130.0;THP-1: 101.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 25: RPMI-8226 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (7.43e-3)" "unprognostic (3.18e-1)" "unprognostic (5.64e-2)" "unprognostic (6.12e-3)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (8.18e-2)" "unprognostic (4.17e-1)" "unprognostic (2.48e-3)" "prognostic unfavorable (2.26e-5)" "unprognostic (1.14e-2)" "unprognostic (9.24e-2)" "unprognostic (3.08e-2)" "unprognostic (5.44e-2)" 8.4 7.9 4.8 12.4 5.0 18.3 11.9 5.2 5.4 11.6 9.3 9.4 3.3 13.1 7.3 4.3 9.1 13.4 10.8 4.6 5.9 6.9 5.3 6.8 16.5 5.2 5.1 8.9 11.5 8.5 12.5 29.3 5.0 8.7 5.5 1.7 5.9 9.7 12.1 5.0 6.0 10.8 5.0 8.1 5.0 5.5 5.0 15.9 17.1 11.5 14.0 12.4 6.9 4.9 0.1 0.0 18.1 33.9 6.6 19.1 0.1 12.5 0.7 14.8 15.3 12.2 0.0 0.1 9.8 68.6 0.0 0.0 29.0 0.0 8.1 0.0 0.2 63.9 3.6 11.3 23.9 0.0 0.0 44.4 0.0 2.5 0.0 0.0 22.9 0.4 0.0 0.0 28.2 0.0 3.3 33.5 31.5 0.0 0.0 76.4 0.0 130.0 1.3 0.0 13.7 27.0 33.3 0.0 21.9 3.0 0.0 101.1 1.4 0.0 3.7 3.8 0.1 0.1 0.0 47.9 0.0 0.2 11.3 0.2 1.7 5.4 22.6 0.4 31.8 32.0 34.6 27.1 5.4 35.2 44.5 29.0 0.9 31.6 0.2 73.7 27.6 21.4 4.8 5.0 5.2 5.4 4.6 5.9 5.2 5.1 5.0 5.0 5.0 4.9 8.4 3.2 5.5 1.0 16.1 2.2 9.0 8.3 1.2 1.0 7.1 13.6 3.9 12.8 6.5 3.7 0.0 22.8 9.2 0.2 5.9 11.1 6.9 8.2 43.7 12.4 1.2 6.7 1.6 15.6 19.8 30.5 0.5 6.5 1.3 25.8 15.4 3.8 12.3 5.0 2.7 1.2 2.0 1.9 0.7 6.6 15.2 6.0 7.2 4.7 5.0 8.3 9.2 4.5 2.0 4.7 0.7 13.5 25.2 5.7 0.0 3.0 7.0 0.6 13.1 13.3 14.5 10.8 12.1 1.9 3.3 15.6 10.9 19.3 0.6 4.9 GRAMD1A "FLJ90346, KIAA1533" ENSG00000089351 "GRAM domain containing 1A" Q96CP6 19 34994784-35026471 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008852, HPA012570" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Cytosol "HPA008852: AB_1079203, HPA012570: AB_2112577" "unprognostic (3.09e-2)" "unprognostic (4.62e-2)" "unprognostic (8.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (3.42e-3)" "unprognostic (5.96e-2)" "unprognostic (4.54e-1)" "unprognostic (5.70e-2)" "unprognostic (1.07e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.95e-12)" "unprognostic (2.04e-1)" "unprognostic (4.40e-1)" "unprognostic (2.90e-2)" "unprognostic (4.36e-2)" 37.9 36.9 17.8 28.0 15.9 23.9 31.1 16.4 24.5 33.2 17.5 30.1 15.1 32.5 5.3 11.6 36.2 16.5 30.3 17.4 18.5 27.4 21.2 58.1 28.8 21.8 20.7 38.4 80.8 17.8 29.2 16.8 21.5 32.6 8.4 5.1 55.6 17.0 47.8 14.5 23.3 18.9 18.2 42.1 35.8 16.6 21.5 18.7 25.4 18.9 12.8 35.7 20.1 17.1 17.3 106.0 21.3 41.5 23.9 27.5 19.6 21.6 27.5 21.8 21.6 39.8 11.9 10.8 41.2 25.2 19.3 9.5 22.2 31.9 8.2 48.9 47.3 24.6 25.5 36.8 48.3 21.7 41.1 46.5 19.9 16.1 26.7 36.6 71.5 54.1 31.8 5.7 16.0 13.2 46.5 23.6 38.6 28.4 12.7 47.1 6.9 10.7 24.8 2.5 30.8 64.4 20.0 12.7 33.7 18.4 19.4 20.6 38.9 34.9 22.3 8.0 29.6 8.8 26.3 22.4 23.5 19.6 27.0 23.1 5.7 5.4 3.5 9.6 7.3 0.6 4.6 2.7 5.1 1.2 3.5 5.4 12.7 5.7 19.9 1.7 4.1 3.8 17.8 15.9 16.4 24.5 17.4 18.5 21.8 20.7 21.5 18.2 21.5 17.1 51.0 22.4 37.3 28.1 23.6 20.8 64.4 15.1 18.2 15.8 22.0 18.7 12.3 0.0 16.1 16.5 16.7 13.1 32.3 3.5 3.9 36.8 1.4 15.3 19.9 63.2 39.4 20.4 8.9 57.8 35.8 25.6 10.7 16.5 9.5 39.5 66.4 5.6 53.8 8.4 12.1 15.0 14.2 39.4 81.6 3.0 25.7 37.7 33.8 15.0 146.0 23.1 19.6 12.5 15.1 41.2 9.6 25.2 40.4 68.6 1.4 15.1 11.5 14.9 13.1 15.4 26.0 1.2 5.7 3.4 15.3 33.1 48.1 50.6 19.7 51.9 GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 143.0;Late spermatids: 212.6;Oligodendrocytes: 124.7;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.0;eosinophil: 3.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 10.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: AB_2674057" "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" 27.6 26.0 29.5 6.5 33.6 10.0 25.0 25.2 32.5 18.2 28.5 27.2 17.2 19.8 10.3 9.5 18.8 21.6 34.8 26.5 40.2 29.3 32.1 20.6 6.0 31.5 41.8 14.2 94.3 10.5 24.3 14.7 40.2 20.1 6.4 83.5 16.5 15.0 57.4 9.1 13.3 16.1 21.6 36.8 17.6 18.1 48.2 2.8 27.8 76.0 4.0 31.0 15.9 33.5 0.3 32.5 51.6 21.1 23.5 17.8 27.6 13.1 11.3 24.9 29.7 19.8 0.4 0.7 22.6 16.7 71.0 3.1 53.5 13.9 12.2 0.4 21.6 56.7 32.6 14.4 49.8 36.0 84.1 46.4 21.0 38.6 37.4 23.9 62.7 3.9 109.5 0.6 18.7 4.0 6.4 48.0 56.9 27.2 55.4 16.8 0.0 0.3 16.0 13.1 22.7 0.2 1.6 8.1 68.7 33.0 27.7 71.6 78.7 21.8 29.6 45.4 50.4 2.1 0.7 0.4 68.9 32.2 75.2 10.0 0.1 3.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 29.5 33.6 25.2 32.5 26.5 40.2 31.5 41.8 40.2 21.6 48.2 33.5 46.3 6.4 8.3 3.9 1.2 7.5 5.3 9.4 7.4 12.1 14.8 9.0 13.5 47.1 5.2 5.5 87.6 4.5 0.3 6.9 1.9 18.3 143.0 5.3 12.4 45.2 0.0 19.0 64.8 24.4 16.5 15.4 5.6 9.7 0.0 0.8 53.2 26.8 1.6 5.0 55.0 2.8 6.1 9.7 5.5 212.6 1.8 4.0 7.2 40.3 0.8 21.8 0.0 41.7 124.7 36.4 3.0 0.4 0.6 22.2 11.2 22.2 2.3 81.9 0.0 9.2 10.9 1.9 16.2 1.2 4.3 2.6 1.5 0.9 3.8 7.0 GRID2IP ENSG00000215045 "Grid2 interacting protein" A4D2P6 7 6497462-6551436 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "brain: 31.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.8;Inhibitory neurons: 2.9;Oligodendrocyte precursor cells: 4.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "thalamus: 31.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "REH: 3.6" "Group enriched" "Detected in many" 5 "cerebellum: 22.4;thalamus: 7.2" "Low region specificity" "Detected in all" HPA045381 Approved "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA045381: AB_10962495" "unprognostic (1.77e-1)" "unprognostic (2.64e-1)" "unprognostic (3.39e-4)" "unprognostic (1.19e-3)" "unprognostic (5.52e-2)" "unprognostic (2.50e-2)" "unprognostic (2.82e-1)" "unprognostic (2.37e-2)" "unprognostic (1.92e-3)" "unprognostic (2.06e-3)" "unprognostic (1.64e-1)" "unprognostic (3.40e-2)" "unprognostic (3.38e-2)" "unprognostic (5.54e-2)" "unprognostic (8.08e-2)" "unprognostic (1.87e-1)" "unprognostic (3.17e-1)" 0.0 0.4 6.7 0.1 6.2 0.2 0.2 10.7 1.4 0.1 0.0 0.3 0.4 0.1 0.0 0.3 0.2 0.1 0.1 0.1 7.9 0.2 0.0 0.2 0.1 2.4 9.8 0.1 0.5 0.5 0.9 0.0 1.9 0.5 0.1 0.5 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.3 0.4 0.3 31.9 0.2 0.3 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.3 0.0 3.6 0.1 0.1 0.0 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 6.2 10.7 1.4 0.1 7.9 2.4 9.8 1.9 0.0 31.9 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.6 0.1 0.2 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.5 0.1 0.0 0.1 0.0 0.4 2.8 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 4.5 1.3 0.1 0.0 0.0 0.3 0.2 0.4 0.1 0.0 1.0 0.0 0.0 0.1 0.8 0.2 1.2 0.0 0.0 0.1 0.9 0.1 0.2 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 GSTO2 ENSG00000065621 "Glutathione S-transferase omega 2" Q9H4Y5 10 104268873-104304950 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 133.1;Early spermatids: 314.6;Late spermatids: 442.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 16.9;CAPAN-2: 17.1;hTCEpi: 16.2;hTERT-HME1: 18.3;OE19: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA048141 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "HPA048141: AB_2680281" "unprognostic (5.77e-2)" "unprognostic (6.69e-2)" "unprognostic (7.15e-2)" "unprognostic (1.80e-1)" "unprognostic (2.48e-1)" "unprognostic (3.11e-2)" "unprognostic (3.12e-1)" "unprognostic (2.15e-1)" "unprognostic (7.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.10e-7)" "unprognostic (4.56e-2)" "unprognostic (3.92e-2)" "unprognostic (1.75e-2)" "unprognostic (3.47e-1)" 0.5 3.5 5.0 0.3 5.7 2.0 5.2 3.4 5.3 4.3 0.4 4.4 2.8 2.2 4.9 11.8 4.3 1.2 0.6 4.4 4.1 14.0 2.8 2.4 0.3 2.2 2.5 5.4 16.7 5.0 14.6 1.0 2.6 8.3 3.1 6.0 7.5 3.2 1.4 14.8 3.5 1.2 1.1 0.5 10.9 35.9 4.3 2.2 7.0 1.3 0.7 3.8 7.5 5.3 10.2 1.4 0.5 0.6 0.6 1.3 1.4 9.6 16.9 4.7 4.9 0.6 17.1 1.6 4.0 0.8 0.5 10.7 0.5 5.3 1.2 1.1 3.2 0.5 3.1 2.4 2.1 0.7 0.7 1.7 16.2 0.3 18.3 1.3 0.8 1.7 1.5 2.9 1.3 12.3 0.1 0.5 1.7 22.1 1.1 0.5 0.7 0.3 4.6 6.5 0.6 1.1 3.3 2.4 2.9 0.8 12.6 0.3 2.4 1.5 5.1 0.6 0.5 2.8 6.4 0.4 1.5 0.8 0.5 0.2 0.1 0.7 0.5 0.2 0.3 0.3 0.5 0.3 0.0 0.5 0.7 0.4 1.7 1.0 0.1 0.3 1.2 0.2 5.0 5.7 3.4 5.3 4.4 4.1 2.2 2.5 2.6 1.1 4.3 5.3 3.6 3.2 21.0 13.1 1.3 34.2 62.1 94.5 50.1 19.0 61.7 78.2 3.0 21.5 46.4 40.5 16.7 14.4 3.8 12.8 133.1 30.6 314.6 26.9 7.6 5.4 54.2 3.6 33.9 63.3 9.9 4.7 31.6 37.6 2.5 3.3 15.7 3.6 1.8 0.0 28.7 34.0 50.8 1.6 3.7 442.8 2.8 2.7 17.8 1.9 2.1 11.1 1.0 24.1 20.1 31.6 29.1 9.8 0.9 25.6 27.1 43.8 31.2 23.0 6.6 3.1 7.4 22.0 8.9 46.0 47.3 6.7 4.3 11.6 40.7 58.0 GTF2F2 "BTF4, RAP30, TFIIF" ENSG00000188342 "General transcription factor IIF subunit 2" P13984 13 45120510-45284893 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006912 Supported Supported Nucleoplasm,Microtubules NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Microtubules "HPA006912: AB_1080256" "unprognostic (3.39e-1)" "unprognostic (2.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.29e-1)" "unprognostic (4.51e-2)" "prognostic unfavorable (1.65e-5)" "unprognostic (3.67e-2)" "unprognostic (3.17e-1)" "unprognostic (3.36e-2)" "unprognostic (2.53e-3)" "unprognostic (2.31e-2)" "unprognostic (4.76e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.53e-3)" "unprognostic (3.94e-2)" "unprognostic (6.44e-3)" 10.9 16.6 12.4 11.0 13.2 18.3 12.9 12.4 14.9 13.5 18.1 18.3 10.4 11.6 15.4 16.5 10.0 8.4 20.0 13.1 13.2 15.0 11.3 9.6 13.4 12.3 13.0 12.1 10.7 14.1 12.9 11.0 12.4 10.7 14.2 9.9 12.2 13.0 25.0 24.9 10.0 12.9 13.5 10.2 11.3 13.3 13.0 14.8 11.4 15.8 14.4 15.5 14.8 15.6 43.2 15.9 29.3 21.8 17.6 25.8 24.3 46.2 30.2 46.1 44.9 26.8 65.7 42.9 25.4 33.9 44.8 46.9 44.3 37.1 66.7 32.6 38.4 50.8 20.7 35.2 28.1 57.0 27.9 21.8 55.9 34.4 57.8 52.0 29.9 32.9 36.6 15.8 125.6 24.2 42.0 65.2 34.8 68.6 38.3 39.0 22.2 24.8 101.4 15.0 15.6 26.0 23.5 22.9 39.8 27.5 18.6 45.9 23.7 38.6 33.1 30.8 79.9 10.0 14.6 42.7 44.9 36.1 41.2 16.2 15.9 29.9 10.3 16.7 12.4 17.3 12.1 12.4 18.8 17.8 13.5 13.5 22.5 18.9 18.9 14.7 14.7 10.1 12.4 13.2 12.4 14.9 13.1 13.2 12.3 13.0 12.4 13.5 13.0 15.6 21.6 41.7 32.1 41.1 36.0 75.1 82.8 80.2 35.9 19.2 27.3 30.2 79.4 10.0 41.6 11.0 4.2 33.0 25.7 29.0 49.0 49.7 93.0 34.9 37.5 27.6 28.2 32.6 23.7 33.6 49.4 28.9 13.7 56.8 39.3 25.6 18.2 21.4 49.1 8.4 35.1 26.4 50.8 27.1 38.2 82.3 24.2 32.0 76.5 36.5 38.2 36.8 27.8 57.8 48.9 48.5 30.3 31.6 30.4 88.3 22.6 42.7 29.4 21.5 6.6 35.6 32.3 68.6 83.9 34.5 72.7 33.8 28.8 33.5 40.7 75.1 GTF3C4 "KAT12, TFIIIC90" ENSG00000125484 "General transcription factor IIIC subunit 4" Q9UKN8 9 132670035-132694953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transcription "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069369 Supported Nucleoplasm,Mitochondria No No "Cluster 40: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Mitochondria "HPA069369: AB_2686130" "unprognostic (7.02e-2)" "unprognostic (9.01e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-2)" "unprognostic (1.58e-1)" "unprognostic (1.76e-1)" "unprognostic (4.77e-1)" "unprognostic (1.92e-2)" "prognostic favorable (2.99e-4)" "unprognostic (1.65e-1)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" 4.9 4.4 4.3 4.6 5.0 6.9 8.4 9.2 4.3 7.3 3.6 5.3 3.9 6.6 5.5 6.7 6.6 5.2 5.8 4.5 5.2 6.0 5.3 5.7 5.0 3.4 4.8 10.3 6.1 9.4 3.2 6.4 3.7 6.2 5.4 5.5 7.3 5.7 5.8 9.8 3.6 6.2 3.6 4.5 5.8 8.3 5.6 8.1 9.5 8.0 6.6 5.0 3.8 3.8 15.2 21.7 25.8 22.5 12.3 14.4 20.0 15.1 18.4 19.6 14.4 25.4 10.9 22.7 9.8 18.6 18.1 33.8 39.8 23.6 21.1 15.4 19.1 19.0 28.9 10.8 12.8 28.6 12.4 11.4 17.6 20.4 26.1 11.6 16.8 15.1 32.7 11.4 14.0 24.6 17.8 13.3 33.1 22.2 21.4 17.6 31.1 20.6 14.3 12.5 36.3 24.6 25.9 25.8 15.9 15.8 35.4 12.1 17.8 32.9 18.7 15.1 21.6 4.9 12.3 25.1 13.5 17.8 20.7 0.0 0.3 0.2 0.5 0.3 0.4 0.5 0.4 0.6 0.2 0.4 0.5 0.5 0.3 0.5 0.2 0.5 0.4 0.2 4.3 5.0 9.2 4.3 4.5 5.2 3.4 4.8 3.7 3.6 5.6 3.8 9.9 19.2 11.5 2.3 7.8 30.7 6.9 6.9 21.6 15.5 19.1 14.7 14.6 1.5 6.7 3.7 14.6 7.5 9.0 6.6 7.9 8.3 6.5 21.5 26.2 11.6 13.1 8.2 3.2 6.3 7.5 13.0 8.6 17.7 1.3 17.1 10.0 8.6 6.3 20.2 3.1 8.1 10.2 7.6 9.3 3.7 19.0 6.3 3.6 1.9 7.1 11.9 7.2 1.0 2.1 5.8 7.0 19.2 10.7 11.6 3.8 6.6 16.2 16.9 0.0 18.8 10.9 16.7 13.8 22.1 40.1 6.4 8.8 18.2 9.0 6.4 GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828822-2882820 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 156.3" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Enteroendocrine cells: 20.4;Granulosa cells: 10.2;Hepatocytes: 20.2" "Cancer enhanced" "Detected in all" "melanoma: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.1;CACO-2: 30.4;Hep G2: 32.6;NTERA-2: 38.4;SK-MEL-30: 87.6;SuSa: 59.0" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA005495: AB_1079035, HPA064686: AB_2685323" "unprognostic (4.45e-2)" "unprognostic (4.21e-2)" "unprognostic (6.41e-3)" "unprognostic (8.50e-2)" "unprognostic (2.07e-3)" "unprognostic (5.16e-1)" "unprognostic (1.74e-2)" "unprognostic (1.18e-1)" "unprognostic (7.43e-3)" "unprognostic (6.74e-2)" "prognostic favorable (3.01e-5)" "unprognostic (9.76e-2)" "unprognostic (6.10e-5)" "unprognostic (1.78e-1)" "unprognostic (5.05e-3)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" 156.3 2.2 10.3 1.9 10.8 0.2 38.9 18.4 8.8 3.0 8.5 3.9 1.5 6.6 1.0 0.9 5.1 2.2 1.4 11.2 18.9 2.0 18.5 0.5 0.6 29.4 24.5 2.5 5.4 1.0 0.8 2.1 27.3 4.0 2.8 1.4 4.7 6.6 0.3 1.9 2.1 3.7 36.0 0.3 4.5 0.9 13.7 0.4 1.7 0.5 0.3 3.7 2.0 35.4 0.1 11.5 39.1 0.2 20.5 0.0 28.5 2.0 6.3 6.1 8.2 30.4 0.6 0.0 3.1 5.2 6.6 0.0 22.5 0.5 6.8 0.2 6.3 0.1 0.7 32.6 6.7 0.0 8.9 8.1 0.4 1.0 0.0 0.2 0.0 0.0 0.3 0.1 6.6 1.9 0.0 1.0 38.4 0.4 0.2 6.1 13.0 0.0 0.0 0.1 0.0 0.7 0.1 0.3 87.6 59.0 4.1 25.4 0.0 0.0 6.7 3.8 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.3 10.8 18.4 8.8 11.2 18.9 29.4 24.5 27.3 36.0 13.7 35.4 0.3 0.0 0.0 10.7 0.2 0.4 1.1 0.5 0.0 1.2 2.1 0.8 1.2 4.3 0.2 0.0 4.2 6.0 0.0 1.2 5.9 1.0 0.4 3.8 1.0 0.3 20.4 0.0 5.9 4.0 7.9 1.6 4.6 0.7 0.0 10.2 0.0 20.2 1.1 0.0 4.9 1.7 0.0 1.0 0.0 0.5 0.6 0.1 3.6 0.0 0.0 1.6 0.0 0.5 0.1 2.1 0.6 3.0 0.0 1.0 0.4 2.4 1.1 0.1 0.0 0.3 1.2 0.3 1.5 0.0 0.3 2.3 0.0 3.2 3.5 0.7 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102646-55110252 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.1" "Group enriched" "Detected in many" 24 "dendritic cells: 739.3;NK-cells: 1543.8;T-cells: 709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 15 "gdT-cell: 941.4;MAIT T-cell: 926.2;memory CD4 T-cell: 250.0;memory CD8 T-cell: 922.7;naive CD8 T-cell: 494.1;NK-cell: 718.8" "Group enriched" "Detected in all" 42 "NK-cells: 718.8;T-cells: 941.4" "Cell line enhanced" "Detected in some" "HL-60: 4.0;JURKAT: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054134, HPA076751" Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054134: AB_2682395, HPA076751: " "prognostic favorable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favorable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" 5.6 6.0 0.9 16.7 0.9 35.3 7.2 0.9 2.5 7.6 1.2 14.7 29.2 14.7 8.8 4.8 4.6 14.0 4.0 0.8 1.0 3.2 15.2 21.9 68.1 1.6 0.9 4.5 1.0 1.3 1.0 3.1 1.1 3.1 17.8 0.0 7.1 3.0 1.7 1.6 27.6 7.2 1.1 51.1 11.7 2.0 1.1 12.4 2.9 1.3 19.2 13.5 2.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 2.5 3.8 941.4 2.3 926.2 3.4 250.0 922.7 3.1 1.3 48.5 494.1 19.9 718.8 4.0 3.2 33.1 712.7 0.9 0.9 0.9 2.5 0.8 1.0 1.6 0.9 1.1 1.1 1.1 1.1 5.1 3.2 18.1 0.0 12.3 0.4 0.1 0.0 2.8 0.0 2.7 2.4 1.6 5.7 3.1 0.0 0.0 0.4 739.3 1.4 0.0 1.6 0.0 1.7 2.7 2.8 0.0 36.2 0.0 0.0 0.2 7.8 20.4 2.1 7.6 0.0 17.9 2.8 0.3 0.0 0.1 1.5 0.0 25.8 2.6 0.0 0.0 12.3 3.6 0.0 12.6 0.0 1543.8 0.0 0.1 0.0 3.9 0.0 40.8 0.1 2.8 3.3 2.9 0.0 0.0 2.6 2.6 0.0 0.1 1.1 1.4 0.7 709.4 0.0 1.8 0.0 GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.2;lymphoid tissue: 37.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2050.2;NK-cells: 1704.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 6765.2" "Lineage enriched" "Detected in all" 5 "dendritic cells: 6765.2" "Cell line enriched" "Detected in some" 6 "HMC-1: 22.0" "CAB000376, HPA003418" Enhanced "Secreted to blood" NA NA 2170 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favorable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" 8.2 1.7 1.2 17.8 1.3 68.2 2.1 1.2 3.9 1.2 1.4 2.5 2.3 7.1 1.6 3.8 1.5 6.5 1.8 1.2 7.9 1.5 4.1 15.3 37.1 1.5 1.5 0.3 1.0 0.7 0.7 3.3 1.6 1.4 2.2 0.0 2.3 1.4 2.0 0.4 4.4 4.3 1.4 28.9 3.5 0.5 1.8 9.7 1.9 1.5 34.6 18.5 1.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.7 2.8 9.9 3.0 5.3 1338.5 4.0 16.0 7.0 95.2 641.6 6.3 3.1 29.1 607.5 43.1 507.8 6.0 6765.2 2.7 1607.1 1.2 1.3 1.2 3.9 1.2 7.9 1.5 1.5 1.6 1.4 1.8 1.3 4.3 6.4 36.0 0.0 15.9 2.8 0.3 0.0 0.0 0.0 0.9 0.8 1.1 4.3 7.4 0.0 0.0 0.4 2050.2 0.6 0.0 1.6 0.0 0.4 0.5 2.7 0.0 11.8 0.0 0.0 0.1 5.1 9.2 0.5 17.7 0.0 4.2 1.2 0.2 0.0 0.0 0.6 0.0 4.8 9.0 0.2 0.0 27.1 42.7 1.0 11.6 0.0 1704.4 0.0 0.1 0.1 2.3 0.0 86.8 0.2 0.6 3.1 4.4 0.0 0.0 1.3 1.3 0.0 0.1 0.4 4.1 0.3 373.8 0.0 0.6 0.1 GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 99.6" "Group enriched" "Detected in many" 4 "dendritic cells: 136.3;T-cells: 301.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 741.6;NK-cell: 505.5" "Group enriched" "Detected in many" 199 "NK-cells: 505.5;T-cells: 741.6" "Cell line enriched" "Detected in single" 10 "JURKAT: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA063181, HPA065895" Enhanced "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA063181: AB_2684955, HPA065895: " "prognostic favorable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" 3.0 3.9 0.1 19.4 0.1 10.5 4.9 0.1 0.4 4.3 0.3 3.4 1.6 4.0 4.5 3.0 2.0 11.6 2.0 0.1 0.2 1.7 10.7 5.9 99.6 0.5 0.2 2.7 1.0 0.8 0.5 0.5 0.3 3.2 4.6 0.0 4.6 1.0 0.2 0.6 7.3 2.2 0.2 30.4 6.5 1.2 0.3 11.9 2.3 0.3 27.8 8.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.9 1.1 164.3 1.0 741.6 0.5 100.2 457.3 0.5 0.5 4.9 77.4 3.1 505.5 0.9 0.9 7.0 95.5 0.1 0.1 0.1 0.4 0.1 0.2 0.5 0.2 0.3 0.2 0.3 0.3 3.8 3.2 7.0 0.0 10.7 1.5 0.1 0.0 1.8 0.0 1.5 1.7 0.1 2.8 0.6 0.0 0.0 0.0 136.3 0.1 0.0 0.0 1.3 0.8 0.4 0.8 0.0 4.4 0.0 0.0 0.0 1.2 4.1 0.8 2.5 0.0 8.6 1.5 0.2 0.0 0.0 0.0 0.0 10.3 2.5 1.2 0.0 6.4 1.8 0.0 5.1 0.0 29.9 0.0 0.1 0.0 0.0 0.0 45.1 0.1 0.2 0.8 0.0 0.0 0.0 1.8 1.7 0.0 0.3 0.2 0.6 0.3 301.9 0.0 0.0 0.1 H2AX H2AFX ENSG00000188486 "H2A.X variant histone" P16104 11 119093854-119095467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 43.7;Cytotrophoblasts: 83.2;dendritic cells: 34.0;Extravillous trophoblasts: 106.6;Hofbauer cells: 45.8;Syncytiotrophoblasts: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012264, HPA041189, HPA051647" Supported Supported "Nucleoplasm,Nuclear speckles" Yes Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear speckles" "CAB012264: AB_297215, HPA041189: AB_2677357, HPA051647: AB_2681563" "unprognostic (1.44e-1)" "unprognostic (1.96e-1)" "unprognostic (6.46e-2)" "unprognostic (6.41e-2)" "unprognostic (3.07e-1)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (2.32e-3)" "unprognostic (1.93e-1)" "unprognostic (3.07e-3)" "unprognostic (6.78e-2)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.47e-9)" "unprognostic (1.21e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" 13.2 20.7 35.2 12.6 37.8 24.9 8.0 39.0 42.2 13.3 20.6 18.6 13.3 14.0 2.1 43.6 13.1 3.1 13.4 33.7 32.3 17.0 13.9 14.3 16.0 43.9 38.9 18.7 11.6 3.4 24.3 11.0 37.8 15.7 4.3 6.6 11.4 4.7 12.4 18.1 18.8 3.5 38.0 24.0 16.1 15.4 37.8 30.5 10.4 3.6 12.0 11.8 15.7 51.8 132.1 77.9 120.3 72.3 10.9 7.9 126.4 146.0 44.0 80.3 70.4 124.0 55.1 89.7 85.9 34.0 60.5 134.0 57.5 41.7 21.5 133.4 161.0 182.2 20.7 129.8 11.4 90.5 108.9 6.7 9.0 34.2 21.0 13.1 40.7 115.4 149.9 143.1 38.9 335.6 207.8 269.9 87.5 60.0 162.6 200.7 141.6 42.7 37.5 56.3 127.6 152.0 116.0 66.6 20.6 20.6 99.8 68.2 50.9 77.7 204.2 63.8 110.2 38.7 40.8 92.3 17.9 145.2 155.0 3.8 1.3 4.2 1.6 0.6 0.8 0.9 1.7 1.7 1.8 0.8 1.1 1.0 0.6 2.2 0.8 0.8 1.6 1.2 35.2 37.8 39.0 42.2 33.7 32.3 43.9 38.9 37.8 38.0 37.8 51.8 43.7 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 83.2 34.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 106.6 9.4 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 64.2 7.2 0.0 0.0 0.0 H2BC4 "H2B.1, H2B/l, H2BFL, HIST1H2BC" ENSG00000180596 "H2B clustered histone 4" P62807 6 26114873-26123926 "Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 18 "neutrophil: 923.6" "Lineage enriched" "Detected in all" 26 "granulocytes: 923.6" "Cell line enhanced" "Detected in all" "K-562: 39.8;SiHa: 75.8;U-2 OS: 51.9;U-266/70: 42.8;U-266/84: 57.1" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 16: U-266 - Nucleosome" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (8.30e-3)" "unprognostic (2.60e-2)" "unprognostic (2.37e-2)" "unprognostic (9.26e-2)" "unprognostic (3.20e-2)" "unprognostic (5.08e-2)" "unprognostic (4.72e-1)" "unprognostic (6.45e-2)" "unprognostic (9.22e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (9.01e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (5.41e-2)" "unprognostic (7.38e-2)" "unprognostic (2.49e-1)" "unprognostic (6.60e-3)" 4.3 3.4 9.5 6.0 17.4 25.0 6.7 11.4 8.8 9.1 9.9 3.1 3.2 1.2 3.6 14.7 7.1 4.6 3.6 10.5 15.0 5.3 13.1 8.0 2.9 20.3 10.9 2.6 2.6 0.9 5.8 7.2 16.3 21.8 2.3 1.5 7.5 0.9 14.5 6.7 3.0 1.2 21.5 5.1 7.0 6.4 9.4 14.9 3.6 8.0 2.3 3.5 10.2 27.6 7.0 4.0 2.1 2.0 1.9 1.1 2.6 6.8 2.5 4.5 3.7 5.6 4.1 2.7 12.5 2.3 3.3 5.2 2.8 2.8 2.2 6.3 2.3 2.2 6.1 9.6 2.6 3.4 8.4 27.3 1.7 1.9 1.1 2.2 1.8 2.1 39.8 21.1 8.6 8.0 7.5 7.2 2.2 7.4 12.4 3.3 3.0 16.3 7.8 1.7 9.4 3.0 75.8 5.8 2.6 5.5 31.8 3.1 5.6 5.5 51.9 3.4 2.8 42.8 57.1 13.2 2.3 8.6 3.8 52.5 9.3 49.9 9.2 10.5 12.4 19.1 13.3 13.0 6.6 35.1 10.3 7.7 923.6 10.5 10.4 22.0 9.3 19.2 9.5 17.4 11.4 8.8 10.5 15.0 20.3 10.9 16.3 21.5 9.4 27.6 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 5.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 7.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 42.8 0.4 0.0 0.0 0.0 HABP4 "IHABP4, SERBP1L" ENSG00000130956 "Hyaluronan binding protein 4" Q5JVS0 9 96450169-96491336 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.3" "Group enriched" "Detected in many" 10 "Early spermatids: 224.6;Late spermatids: 808.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.9;T-cells: 1.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055969, HPA062366" Enhanced Supported "Nuclear membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" Cytosol "HPA055969: AB_2682991, HPA062366: " "unprognostic (1.67e-1)" "unprognostic (7.99e-2)" "unprognostic (2.12e-3)" "unprognostic (2.40e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (1.36e-2)" "unprognostic (3.63e-2)" "unprognostic (3.49e-1)" "unprognostic (2.42e-2)" "unprognostic (1.75e-3)" "unprognostic (1.36e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.25e-1)" "unprognostic (1.40e-1)" "unprognostic (4.93e-2)" "unprognostic (3.62e-2)" 21.9 12.8 62.7 7.0 70.1 1.8 16.8 55.1 73.3 16.1 40.8 19.2 3.0 13.5 7.0 7.6 13.5 8.8 28.1 62.3 63.9 27.0 7.6 10.8 8.3 66.2 65.4 15.6 6.6 12.9 22.6 3.5 66.1 12.5 4.2 16.0 6.2 11.1 16.8 9.5 10.4 9.7 59.5 7.5 12.5 43.9 61.3 4.6 13.7 13.4 5.3 18.4 13.0 68.9 14.8 16.6 20.6 22.3 44.7 37.9 14.6 19.5 21.8 14.5 15.7 24.9 24.0 7.5 9.4 29.4 45.9 10.6 17.4 3.7 11.6 9.0 10.3 2.9 7.8 42.0 22.7 0.7 3.0 15.5 6.7 16.5 13.0 21.9 10.4 8.4 3.4 21.6 26.4 15.2 0.3 4.6 9.6 20.5 15.8 7.6 17.9 0.3 24.8 6.4 13.0 8.8 10.6 6.2 32.5 15.2 4.5 3.2 17.8 19.8 4.6 36.6 16.8 13.2 14.0 3.3 15.9 5.9 29.8 0.0 0.0 0.0 0.5 0.1 0.5 1.9 1.6 1.3 0.0 1.1 1.1 1.1 0.1 0.4 0.3 0.0 1.3 0.2 62.7 70.1 55.1 73.3 62.3 63.9 66.2 65.4 66.1 59.5 61.3 68.9 22.2 0.0 7.4 27.1 5.9 11.5 10.8 0.9 4.0 22.6 3.8 6.9 11.0 14.3 5.5 18.4 0.0 2.5 5.5 0.9 17.6 4.7 224.6 7.3 9.0 14.6 13.1 0.8 47.4 5.8 7.4 13.3 1.5 8.1 1.3 13.0 15.0 6.3 6.6 23.5 33.2 0.9 4.1 1.3 9.3 808.8 13.7 6.0 17.8 10.3 2.7 22.2 3.1 18.6 37.5 6.3 0.0 23.7 5.1 10.0 1.1 43.7 1.8 15.6 6.6 5.8 26.4 26.8 15.4 0.9 8.0 1.4 13.3 3.0 1.3 6.0 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 143.0 54.1 23.2 20.9 23.8 27.4 74.9 24.6 26.3 37.9 33.5 101.2 84.4 49.8 24.9 34.2 56.2 24.0 175.6 22.9 27.2 140.2 225.5 22.8 22.2 24.7 26.3 54.3 42.1 40.2 18.0 13.7 26.0 35.4 90.8 10.4 55.9 42.4 249.7 28.0 89.1 72.7 26.0 18.0 60.7 27.9 24.9 76.0 37.7 280.3 28.5 34.1 28.7 28.0 32.2 27.9 64.3 46.2 149.2 48.2 27.0 43.1 68.5 49.6 48.9 21.2 60.9 185.0 23.5 38.8 34.6 42.0 85.5 64.5 55.5 49.6 37.2 39.9 50.5 48.9 24.3 88.2 17.0 50.4 34.1 35.1 32.3 41.4 34.4 127.1 53.1 98.7 57.3 58.9 163.6 36.7 29.0 147.8 30.1 113.5 84.3 89.2 54.5 129.4 73.2 43.1 41.1 161.9 45.6 37.0 77.4 70.8 20.6 35.5 18.9 48.5 26.7 52.1 63.3 80.6 47.0 60.2 27.0 0.0 11.1 11.4 17.2 14.2 22.1 31.4 19.5 20.7 36.8 27.1 22.4 22.2 1.2 36.7 20.1 41.7 17.7 16.3 23.2 23.8 24.6 26.3 22.9 27.2 24.7 26.3 26.0 26.0 24.9 28.0 17.3 28.9 33.8 11.1 25.7 15.6 54.2 65.8 41.5 6.9 46.5 56.1 225.6 52.9 48.1 35.0 4.2 41.0 18.3 164.7 160.4 43.3 196.8 41.4 22.6 17.5 32.4 65.6 15.1 32.2 44.7 28.2 52.5 26.1 10.8 63.9 21.0 272.4 116.5 6.7 18.9 93.3 36.7 37.8 11.8 108.5 46.3 25.3 21.4 12.2 15.3 26.8 8.2 9.5 9.9 23.0 100.8 35.3 32.0 33.9 383.0 318.8 70.8 6.8 39.5 21.7 38.2 22.4 20.3 64.0 18.2 17.0 19.6 66.3 194.2 49.1 HASPIN GSG2 ENSG00000177602 "Histone H3 associated protein kinase" Q8TF76 17 3723903-3726699 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 5.3;testis: 7.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;Extravillous trophoblasts: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA027422, HPA030698" Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027422: AB_10601812, HPA030698: AB_2673575" "unprognostic (1.15e-2)" "unprognostic (2.78e-2)" "unprognostic (7.06e-2)" "unprognostic (2.14e-2)" "unprognostic (8.05e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-4)" "unprognostic (1.57e-2)" "unprognostic (6.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "unprognostic (3.82e-3)" "unprognostic (0.00e+0)" "unprognostic (5.65e-3)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" 0.2 0.1 0.0 1.8 0.2 6.0 0.4 0.0 0.1 0.2 0.2 1.1 1.5 0.2 0.1 1.3 0.3 0.2 0.1 0.0 0.0 0.1 0.1 1.4 4.2 0.1 0.1 0.1 0.2 0.0 0.0 0.6 0.1 0.3 1.0 0.0 0.4 0.0 0.6 0.7 1.8 0.4 0.0 1.7 0.9 7.3 0.2 5.3 0.3 0.1 5.1 0.3 0.5 0.2 11.3 12.2 11.1 12.5 0.7 1.4 9.3 10.2 7.8 19.7 19.3 9.6 4.6 27.7 5.7 5.7 7.9 18.0 20.1 9.9 18.7 0.1 16.7 13.8 9.9 5.8 0.5 8.1 13.7 0.9 0.8 14.9 9.2 2.4 9.1 21.6 12.4 23.7 10.1 5.9 16.4 4.8 9.8 8.7 8.3 16.8 13.9 7.4 3.0 7.8 4.4 6.5 8.9 6.1 3.5 9.6 6.1 7.5 4.7 8.7 9.9 9.8 18.1 4.5 5.4 13.4 5.1 11.5 10.7 0.1 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 HCN2 "BCNG-2, BCNG2, HAC-1" ENSG00000099822 "Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2" Q9UL51 19 589881-617159 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 146.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 60.4;Horizontal cells: 40.4;Inhibitory neurons: 18.7;Oligodendrocytes: 62.1;Rod photoreceptor cells: 14.9" "Group enriched" "Detected in many" 6 "glioma: 8.7;melanoma: 5.7;renal cancer: 2.8;testis cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 29.9;HeLa: 15.8;MCF7: 28.4;U-138 MG: 20.2;U-87 MG: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (8.69e-2)" "unprognostic (3.97e-3)" "unprognostic (3.31e-4)" "unprognostic (1.44e-1)" "unprognostic (2.44e-1)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" "unprognostic (5.32e-2)" "unprognostic (1.19e-3)" "unprognostic (8.00e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.07e-1)" "unprognostic (1.41e-1)" "unprognostic (5.53e-4)" "unprognostic (9.72e-3)" 0.1 4.2 34.9 0.2 58.1 0.4 0.1 84.7 111.8 0.1 0.0 0.6 0.1 0.1 0.2 1.6 0.0 0.1 11.6 38.2 56.6 1.3 0.2 0.2 0.3 86.6 76.7 0.1 0.3 3.4 12.8 0.1 84.9 0.3 0.0 7.5 0.3 0.1 0.1 0.9 0.4 0.1 38.2 0.4 0.4 3.1 146.0 0.1 0.1 0.0 0.3 0.1 0.4 66.9 0.1 29.9 0.3 1.0 3.1 2.1 1.0 2.1 2.4 0.8 0.2 4.3 0.3 0.0 6.5 2.9 2.1 0.2 0.6 0.1 0.1 5.1 12.6 0.0 15.8 0.4 2.2 0.3 5.6 5.6 0.5 0.2 0.1 0.9 0.1 0.7 1.8 0.2 2.1 28.4 0.1 0.0 1.4 0.7 0.8 0.2 0.1 0.7 0.5 0.9 11.3 5.8 7.3 0.1 2.3 0.5 5.9 1.0 2.8 20.2 3.0 0.4 8.4 0.5 0.4 0.2 41.7 1.4 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 58.1 84.7 111.8 38.2 56.6 86.6 76.7 84.9 38.2 146.0 66.9 0.5 0.0 0.0 2.0 0.6 0.6 0.0 0.0 1.2 60.4 0.7 0.9 4.1 0.0 0.0 0.0 2.1 0.0 1.6 0.3 0.0 0.1 0.1 0.6 0.4 0.9 1.2 2.7 12.8 0.0 0.3 0.2 0.0 1.2 0.0 0.2 0.7 0.1 0.1 40.4 18.7 0.0 0.0 1.3 0.3 0.4 0.0 1.1 0.0 2.8 0.0 2.7 0.0 5.5 62.1 0.1 0.0 0.7 1.4 0.1 0.0 0.3 0.0 14.9 0.0 0.1 0.5 0.1 1.7 4.5 0.6 0.3 1.2 0.1 0.1 0.1 HDGFL3 "Hdgfrp3, HRP-3" ENSG00000166503 "HDGF like 3" Q9Y3E1 15 83112738-83207823 "Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 96.9;Breast glandular cells: 34.3;Endometrial ciliated cells: 34.2;Endometrial stromal cells: 48.4;Granulosa cells: 41.4;Theca cells: 48.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040719 Approved Supported Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA040719: AB_2677097" "unprognostic (1.28e-3)" "unprognostic (1.13e-1)" "unprognostic (3.52e-2)" "unprognostic (3.38e-2)" "unprognostic (1.53e-1)" "unprognostic (2.55e-2)" "unprognostic (1.91e-2)" "unprognostic (2.95e-2)" "unprognostic (2.99e-2)" "unprognostic (4.68e-2)" "unprognostic (1.93e-3)" "unprognostic (3.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.06e-2)" "unprognostic (3.55e-1)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" 6.3 5.9 11.1 2.9 12.0 2.4 5.6 11.6 14.9 5.0 7.2 7.0 1.2 6.0 8.3 3.6 4.7 4.0 5.7 11.8 11.5 4.8 0.8 5.1 2.9 10.5 10.5 5.0 1.7 17.7 6.8 3.0 10.5 4.9 2.6 8.5 2.4 4.6 2.5 2.0 2.9 5.3 11.1 3.4 2.9 9.7 11.8 4.3 6.5 2.5 2.2 5.6 3.8 10.7 7.2 6.2 17.9 9.3 7.4 10.1 5.9 6.7 11.9 7.0 7.3 0.5 13.2 0.1 8.0 1.8 7.5 2.9 19.9 10.3 10.1 33.5 10.2 11.6 3.0 0.1 10.3 0.4 1.8 6.0 8.4 8.0 13.9 10.8 17.0 12.4 9.0 0.3 13.2 7.4 7.1 0.7 13.3 0.0 3.5 0.1 17.4 0.1 10.5 14.6 22.5 17.1 10.1 2.4 8.9 12.9 2.8 1.3 14.7 14.5 10.8 3.0 20.9 2.1 0.8 8.6 6.7 5.5 10.0 0.7 0.3 1.0 0.5 0.1 0.0 0.1 0.1 0.1 0.2 0.2 0.2 0.2 0.8 1.8 0.1 0.2 0.0 0.1 11.1 12.0 11.6 14.9 11.8 11.5 10.5 10.5 10.5 11.1 11.8 10.7 96.9 12.8 17.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 34.3 27.3 0.0 0.0 10.5 20.2 0.0 0.3 14.1 0.0 15.6 21.1 0.0 34.2 48.4 25.8 0.0 0.0 0.0 22.9 0.6 15.4 0.0 25.6 5.1 41.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 23.6 0.0 0.0 3.1 0.0 0.0 0.3 9.5 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.3 3.5 48.1 0.0 0.0 HDX "CXorf43, FLJ30678" ENSG00000165259 "Highly divergent homeobox" Q7Z353 X 84317874-84502479 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.1;Inhibitory neurons: 56.7;Oligodendrocyte precursor cells: 45.8;Oligodendrocytes: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047189 Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA047189: AB_10965463" "unprognostic (7.26e-2)" "unprognostic (3.53e-2)" "unprognostic (1.64e-2)" "unprognostic (1.51e-5)" "unprognostic (3.23e-4)" "unprognostic (5.52e-2)" "unprognostic (1.44e-1)" "unprognostic (6.46e-2)" "unprognostic (1.13e-1)" "unprognostic (1.81e-1)" "unprognostic (6.40e-6)" "unprognostic (1.14e-1)" "unprognostic (7.20e-2)" "unprognostic (3.86e-3)" "unprognostic (2.34e-1)" "unprognostic (1.30e-2)" "unprognostic (3.66e-2)" 1.3 1.6 0.6 0.7 0.9 0.0 1.6 2.9 1.6 1.8 0.0 1.3 0.3 1.8 1.5 1.1 1.6 1.3 1.1 0.8 1.3 1.1 1.0 1.0 0.5 1.1 0.6 2.1 0.5 1.2 1.2 0.3 1.0 1.4 1.1 1.8 1.3 1.5 0.4 0.4 0.7 1.7 0.8 1.0 0.7 1.0 0.6 0.4 1.4 0.4 0.6 1.3 1.0 1.3 0.0 1.5 7.5 0.0 4.4 3.9 0.0 2.3 3.2 5.0 4.9 0.3 0.8 0.0 0.4 1.8 6.2 0.3 0.1 0.5 4.3 0.0 0.3 0.0 1.4 0.0 3.6 0.0 0.0 2.2 0.0 3.1 2.2 3.2 5.4 0.0 0.0 0.0 4.9 0.1 0.0 0.0 4.7 0.0 2.2 0.0 5.7 0.0 2.4 1.0 0.2 3.9 0.0 0.1 0.0 2.7 0.4 0.0 6.4 2.5 1.9 0.8 2.2 0.1 0.0 0.0 1.5 0.0 0.9 0.0 2.3 0.0 0.7 3.5 0.1 1.8 0.2 0.2 3.2 0.5 0.6 0.4 0.0 0.9 3.5 0.3 0.1 0.6 0.6 0.9 2.9 1.6 0.8 1.3 1.1 0.6 1.0 0.8 0.6 1.3 7.8 0.0 2.7 19.2 2.8 2.5 23.1 2.8 5.7 9.4 4.8 5.2 1.9 1.5 3.5 5.5 12.5 0.0 2.7 1.7 0.0 7.0 8.7 2.9 7.1 6.7 7.1 0.4 51.1 1.8 0.0 7.7 2.0 6.6 1.3 4.1 1.8 0.7 1.0 6.7 56.7 1.5 0.0 1.9 3.6 2.1 4.1 4.1 0.0 20.6 3.8 4.1 1.0 45.8 26.5 2.9 1.9 3.4 1.2 12.4 0.5 2.9 1.3 5.3 0.0 8.8 7.5 2.4 0.3 3.0 1.7 0.1 1.5 4.7 1.3 19.6 HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.2;Endothelial cells: 47.6;Extravillous trophoblasts: 112.6;Skeletal myocytes: 74.5" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cell line enhanced" "Detected in many" "HEK 293: 125.7;PC-3: 28.8;SK-MEL-30: 93.3;WM-115: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" 21.1 2.2 17.4 2.1 23.0 0.6 19.0 19.4 19.1 7.2 9.6 6.7 1.7 3.5 0.9 2.8 3.9 4.2 23.9 18.4 20.3 2.8 2.8 15.2 2.2 18.1 21.0 2.0 3.4 3.3 18.4 17.8 19.3 6.0 2.6 5.3 10.1 1.7 19.5 4.2 5.8 3.2 19.1 2.4 4.8 3.1 22.8 3.4 6.5 16.2 2.5 9.3 5.2 15.4 1.7 0.1 1.1 9.1 0.8 0.7 22.0 2.1 2.1 0.3 0.3 0.1 0.1 3.3 2.3 1.0 1.0 4.6 4.9 0.1 0.2 0.5 125.7 0.0 4.1 2.1 1.4 0.0 0.7 1.3 3.7 0.1 16.2 0.4 3.4 0.0 9.0 3.6 1.3 0.1 0.0 0.5 0.1 0.3 28.8 0.0 4.6 3.3 0.4 3.9 5.2 14.6 0.1 2.4 93.3 19.6 0.1 0.1 2.0 0.7 2.4 0.0 1.8 3.3 0.7 0.2 3.4 0.0 31.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 1.3 0.0 0.0 0.0 17.4 23.0 19.4 19.1 18.4 20.3 18.1 21.0 19.3 19.1 22.8 15.4 105.2 0.0 1.8 15.0 0.8 3.2 3.4 27.6 2.8 6.8 8.6 12.2 4.3 0.0 19.5 0.0 0.0 6.8 1.8 5.3 15.6 2.6 4.6 12.6 4.1 47.6 36.8 0.0 7.7 1.2 112.6 5.3 1.5 33.5 10.8 1.9 41.0 0.9 1.8 21.9 8.0 2.0 26.4 0.6 5.7 3.2 0.0 2.3 33.8 20.6 0.0 10.9 0.0 18.6 1.0 0.7 7.5 0.4 0.8 1.7 0.2 0.4 7.7 12.2 0.0 74.5 12.1 0.6 15.4 3.4 3.0 23.4 1.1 1.5 2.5 2.6 HHAT "FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn" ENSG00000054392 "Hedgehog acyltransferase" Q5VTY9 1 210328252-210676296 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 25.8;Excitatory neurons: 47.7;Microglial cells: 20.6;Oligodendrocytes: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Group enriched" "Detected in many" 5 "B-cells: 1.8;dendritic cells: 3.7;T-cells: 1.3" "Cell line enhanced" "Detected in many" "HMC-1: 13.6;LHCN-M2: 11.6;RH-30: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016462 Approved Approved "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA016462: AB_2669360" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (1.86e-1)" "unprognostic (5.02e-3)" "unprognostic (8.89e-3)" "unprognostic (4.81e-2)" "unprognostic (3.32e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (1.67e-3)" "unprognostic (1.43e-1)" "unprognostic (4.13e-3)" "prognostic favorable (8.47e-7)" "unprognostic (2.55e-1)" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (5.67e-2)" 2.1 6.5 1.1 0.6 1.1 0.4 3.3 0.3 1.6 3.4 3.6 2.3 1.1 2.5 3.1 2.8 2.8 2.2 2.4 1.0 0.4 4.0 2.7 2.1 0.8 0.7 0.8 2.1 2.3 1.7 3.2 1.3 0.6 4.0 1.3 1.7 4.4 2.0 0.3 3.4 2.5 1.1 0.9 2.2 1.8 2.5 0.6 2.0 4.6 0.2 0.8 3.1 2.9 0.9 0.8 0.9 2.3 1.3 1.0 1.3 4.8 1.2 1.1 1.9 3.1 0.2 0.9 0.0 1.2 0.9 3.1 0.6 0.5 0.5 2.2 1.7 1.2 0.0 0.1 1.1 0.2 0.3 13.6 1.2 2.7 1.6 1.2 3.2 0.3 1.2 0.0 0.0 11.6 1.2 0.6 0.0 0.6 0.7 0.1 1.3 12.4 0.0 7.5 2.6 1.9 7.8 2.1 0.0 6.0 5.9 4.0 0.7 1.7 2.8 8.5 1.6 4.7 3.8 0.2 0.0 1.1 0.8 2.3 0.0 0.3 0.0 0.7 0.4 1.3 1.5 0.9 0.8 0.4 1.8 0.0 0.2 0.0 0.1 0.1 3.7 0.2 0.4 1.1 1.1 0.3 1.6 1.0 0.4 0.7 0.8 0.6 0.9 0.6 0.9 2.0 0.0 2.4 25.8 5.3 2.2 5.7 2.8 6.8 0.5 5.8 2.4 2.4 4.3 1.2 9.2 0.0 4.6 13.9 1.9 3.9 2.6 1.2 8.8 2.6 2.0 0.0 0.4 47.7 0.7 3.6 3.0 2.6 5.8 0.0 4.6 3.6 2.5 1.9 0.0 11.8 2.7 4.1 2.9 0.5 0.5 1.2 1.5 0.0 20.6 1.0 15.6 0.0 17.1 26.0 1.2 2.1 0.4 2.2 3.7 2.3 0.6 12.9 0.5 0.0 1.7 1.7 0.3 1.3 3.1 2.6 2.2 2.8 0.4 2.0 5.2 HIVEP1 "CIRIP, CRYBP1, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A" ENSG00000095951 "HIVEP zinc finger 1" P15822 6 12008762-12164999 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050724, HPA067457" Approved Supported "Nucleoplasm,Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies, Mitochondria, Cytosol" "HPA050724: AB_2616457, HPA067457: " "unprognostic (2.55e-1)" "unprognostic (5.85e-2)" "unprognostic (1.15e-1)" "unprognostic (6.03e-2)" "unprognostic (1.75e-2)" "unprognostic (5.65e-3)" "unprognostic (4.83e-2)" "unprognostic (1.38e-1)" "unprognostic (2.20e-1)" "unprognostic (1.85e-1)" "unprognostic (5.69e-2)" "unprognostic (1.98e-1)" "unprognostic (4.40e-2)" "unprognostic (3.01e-2)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (2.38e-1)" 7.2 2.3 0.8 8.0 3.0 16.7 5.5 0.7 3.0 7.4 6.5 6.4 5.0 5.9 4.5 7.4 6.1 7.3 3.8 2.2 0.8 4.5 11.7 6.3 8.0 1.3 2.8 6.5 6.7 10.5 3.3 4.9 0.5 6.9 6.6 5.8 4.8 5.8 2.8 5.7 5.2 6.2 0.0 6.0 4.9 4.8 1.2 9.1 4.9 6.2 8.3 9.3 3.3 1.6 8.1 5.9 7.5 4.2 5.8 7.3 7.2 6.4 5.5 5.2 5.7 3.8 4.2 6.7 13.6 7.8 12.4 7.6 7.4 9.2 7.1 14.6 4.3 3.1 5.6 3.7 4.7 3.7 2.5 5.1 9.0 10.6 16.3 11.0 15.5 4.6 32.9 7.5 11.5 6.0 5.9 3.3 6.4 2.8 2.7 3.2 9.8 10.7 3.1 8.7 7.1 5.2 15.9 12.8 4.3 16.6 7.6 4.7 25.2 13.0 5.8 12.3 7.4 30.0 27.3 12.0 4.0 4.8 5.5 2.4 1.8 2.1 1.2 2.0 0.9 3.1 2.0 0.8 1.2 4.8 3.4 2.1 11.7 3.3 5.2 9.0 4.4 0.7 0.8 3.0 0.7 3.0 2.2 0.8 1.3 2.8 0.5 0.0 1.2 1.6 40.2 28.9 16.9 74.7 35.6 32.2 25.4 7.4 30.7 20.4 12.3 10.9 10.4 17.2 17.6 7.3 12.5 3.4 18.7 17.5 3.9 5.6 2.5 37.7 16.4 20.3 10.8 6.5 94.6 7.2 1.8 25.2 22.4 51.0 7.6 7.0 6.4 12.3 5.9 21.9 68.3 14.4 4.1 9.6 47.9 1.8 3.7 23.1 19.6 44.0 29.6 13.1 5.2 59.3 25.0 11.5 10.3 4.5 33.6 25.2 6.7 2.5 16.7 9.7 0.0 21.0 17.1 3.9 3.5 18.7 33.4 5.2 18.8 6.6 8.6 23.7 HIVEP3 "FLJ16752, KBP-1, KBP1, KIAA1555, KRC, Schnurri-3, SHN3, ZAS3, ZNF40C" ENSG00000127124 "HIVEP zinc finger 3" Q5T1R4 1 41506365-42035925 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.6" "Group enriched" "Detected in many" 5 "Astrocytes: 83.9;Excitatory neurons: 219.6;Inhibitory neurons: 271.9;Microglial cells: 163.9;Oligodendrocyte precursor cells: 83.9;Oligodendrocytes: 196.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 18.8;hTEC/SVTERT24-B: 9.5;Karpas-707: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005728 Approved Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA005728: AB_10612117" "unprognostic (2.87e-3)" "unprognostic (2.38e-2)" "unprognostic (4.65e-2)" "unprognostic (2.56e-1)" "unprognostic (1.55e-2)" "unprognostic (6.50e-2)" "unprognostic (2.70e-3)" "unprognostic (3.73e-1)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "unprognostic (2.07e-8)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" 1.6 0.6 0.8 2.1 2.1 1.6 1.4 1.4 1.6 0.4 0.0 0.5 0.4 0.4 0.3 1.9 0.5 0.7 0.8 2.0 0.0 1.0 0.3 1.9 1.7 0.7 0.4 0.5 0.8 0.4 2.1 0.6 1.0 1.4 0.5 0.6 1.6 0.3 0.6 4.6 0.6 0.8 0.1 1.1 0.7 0.3 0.5 6.6 1.5 0.4 2.1 1.8 0.5 0.3 1.9 0.6 0.2 1.8 2.2 1.0 0.0 0.9 0.2 2.3 4.0 0.1 0.3 4.0 0.6 1.0 1.5 2.7 0.4 0.4 3.1 18.8 0.5 0.2 0.9 0.0 0.4 0.3 0.3 5.6 0.4 9.5 1.1 0.6 0.5 1.3 0.0 11.0 1.8 1.2 3.0 0.8 0.6 0.6 2.3 2.0 2.9 2.2 1.5 0.4 2.0 0.6 2.6 0.7 0.5 1.1 0.9 3.4 3.4 2.0 2.2 0.6 4.6 3.3 1.4 2.6 8.1 0.2 7.5 0.0 0.5 0.0 0.6 1.1 0.1 0.1 0.2 0.3 0.4 0.4 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.4 0.8 2.1 1.4 1.6 2.0 0.0 0.7 0.4 1.0 0.1 0.5 0.3 5.9 6.4 10.5 83.9 9.6 23.7 26.5 4.3 17.6 16.4 15.1 11.0 6.9 5.7 8.2 1.8 2.1 0.4 17.6 3.5 1.9 3.1 9.9 1.2 7.7 7.5 3.6 4.4 219.6 2.7 4.4 11.1 1.5 2.8 1.3 0.2 11.4 2.5 6.2 25.2 271.9 1.2 2.0 6.5 17.3 31.9 8.7 15.0 5.4 163.9 9.1 16.0 27.8 83.9 196.0 3.1 0.1 4.1 3.3 15.5 1.9 3.2 1.1 3.5 6.6 23.9 7.4 11.3 8.6 23.7 8.7 0.8 14.5 10.0 0.9 11.1 HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 129.3;lymphoid tissue: 76.6" "Group enriched" "Detected in some" 13 "Early spermatids: 11.1;Hofbauer cells: 34.5;Kupffer cells: 43.9;Macrophages: 38.8;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4" "Immune cell enhanced" "Detected in many" "basophil: 569.7" "Group enriched" "Detected in many" 13 "granulocytes: 569.7;monocytes: 200.9" "Cell line enriched" "Detected in some" 5 "U-937: 20.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2000000 "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA056743: AB_2683222" "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavorable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" 8.4 4.5 0.0 19.0 0.2 129.3 2.6 1.4 1.6 0.8 0.2 2.5 2.0 1.0 0.1 0.9 5.1 2.1 4.0 0.2 0.0 1.8 5.2 25.1 4.2 0.0 0.0 1.0 1.5 0.1 0.7 2.8 0.0 1.1 1.4 0.1 1.5 0.3 0.9 0.5 3.1 7.9 0.0 76.6 2.1 1.3 2.4 1.4 1.3 0.5 0.7 4.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.5 0.1 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.6 0.0 569.7 92.5 204.8 0.3 179.4 0.2 0.4 0.2 0.1 30.2 0.2 0.1 0.1 32.2 0.2 200.9 1.4 0.2 43.6 0.0 0.2 1.4 1.6 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 11.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.4 1.3 0.0 0.4 0.2 34.5 0.0 0.4 0.0 0.0 43.9 0.9 1.8 0.0 38.8 0.0 1.0 14.6 0.0 2.1 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.0 HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29945884 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 3747.8;Proximal enterocytes: 5267.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 1363.9;fHDF/TERT166: 360.3;HBEC3-KT: 366.7;RPMI-8226: 372.1;U-266/70: 344.6" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" 635.4 714.2 15.0 34.8 15.5 137.7 566.7 14.7 36.5 504.9 18.0 737.5 278.3 476.1 181.1 366.8 390.3 239.9 473.4 14.6 17.0 687.0 392.0 1007.3 132.0 19.1 15.8 338.8 200.0 18.5 406.5 52.1 16.5 370.9 94.6 9.9 364.1 1.2 246.5 673.3 959.1 14.5 16.8 1413.1 442.2 132.6 18.0 138.9 531.9 14.5 178.3 412.3 466.8 18.3 1363.9 35.0 0.0 0.0 205.9 193.7 1.4 1.4 2.5 2.1 2.3 0.2 0.1 4.0 0.6 360.3 179.1 31.2 0.2 366.7 0.5 3.1 13.5 237.5 9.5 7.4 11.2 0.5 14.4 2.0 0.0 2.5 1.1 0.6 0.2 177.8 0.4 1.4 0.5 0.0 1.1 24.3 2.9 0.2 4.1 27.5 2.5 372.1 246.7 276.5 0.6 12.4 29.3 0.2 11.8 82.8 1.6 30.4 5.8 18.7 0.8 5.8 4.0 344.6 92.6 77.7 0.4 199.9 0.2 321.6 119.0 182.7 164.7 95.5 134.8 96.9 125.4 146.3 18.6 64.3 86.5 119.2 248.7 133.1 109.6 54.6 222.2 191.9 15.0 15.5 14.7 36.5 14.6 17.0 19.1 15.8 16.5 16.8 18.0 18.3 1622.4 371.8 478.6 22.9 1316.2 856.4 886.2 1417.5 228.8 30.8 289.6 188.5 147.4 936.5 952.5 503.9 6.2 18.3 1879.4 2631.8 88.0 3747.8 52.2 239.4 374.0 1717.8 955.2 499.4 3.6 1310.0 18.5 743.5 853.7 556.2 603.0 253.3 1266.2 276.4 1840.9 37.0 19.3 1755.3 1265.4 1575.0 1124.0 95.6 704.6 1419.1 635.0 67.5 3258.0 170.4 3201.9 49.3 16.1 1802.9 2452.4 484.1 1110.7 1026.6 5267.3 294.9 609.6 24.4 558.8 397.3 579.2 197.4 23.8 216.5 947.7 31.7 2234.9 1021.3 1225.4 1262.8 HLA-B AS ENSG00000234745 "Major histocompatibility complex, class I, B" P01889 6 31353872-31357188 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 2493.7" "Cell type enhanced" "Detected in all" "monocytes: 5683.6;NK-cells: 7881.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 638.3;EFO-21: 547.1;U-266/70: 1285.6;U-698: 377.2" CAB015418 Enhanced NA NA 190000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB015418: AB_831547" "unprognostic (2.87e-2)" "unprognostic (1.49e-1)" "unprognostic (4.90e-2)" "unprognostic (2.65e-2)" "unprognostic (1.86e-1)" "unprognostic (1.81e-1)" "unprognostic (5.16e-3)" "unprognostic (8.51e-2)" "prognostic favorable (2.90e-4)" "unprognostic (2.69e-3)" "unprognostic (3.05e-2)" "unprognostic (1.59e-1)" "unprognostic (9.28e-3)" "unprognostic (3.27e-1)" "unprognostic (7.83e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-2)" 944.9 581.6 5.5 429.4 8.1 53.5 850.0 5.5 14.4 552.0 6.0 912.0 4.7 567.1 222.1 434.4 488.6 461.2 563.1 4.6 6.7 731.7 488.9 1646.3 1061.9 9.6 10.4 296.9 268.7 24.2 288.3 106.6 7.5 439.2 238.5 8.1 485.9 3.8 237.9 936.4 1295.6 75.4 7.7 2493.7 540.1 132.6 6.7 4.4 593.2 3.8 414.9 476.2 582.0 7.9 638.3 0.0 0.0 0.1 13.5 98.9 3.8 0.5 1.2 0.5 1.1 0.0 1.9 22.7 547.1 111.0 203.2 231.9 116.4 112.4 0.0 2.3 29.9 8.3 0.8 0.0 79.8 0.2 2.4 200.2 0.5 0.0 13.9 183.3 0.4 39.8 1.3 30.2 0.0 0.3 1.5 161.4 0.6 0.0 0.1 19.7 3.4 4.7 163.5 0.6 0.9 3.7 5.5 1.4 1.4 0.2 32.6 6.2 134.7 21.4 4.8 4.9 2.3 1285.6 291.0 377.2 1.1 6.5 0.6 141.1 196.5 232.6 233.0 163.6 215.7 162.4 194.8 198.8 150.8 113.0 150.9 212.0 420.5 179.3 123.6 127.3 213.1 400.2 5.5 8.1 5.5 14.4 4.6 6.7 9.6 10.4 7.5 7.7 6.7 7.9 2836.3 913.5 1007.9 14.0 2936.9 1165.9 761.2 1139.6 396.1 27.7 533.2 550.2 168.5 1382.6 948.3 388.1 6.2 31.4 3876.2 3264.3 68.4 4206.8 63.9 311.6 349.2 2480.7 836.0 550.3 1.4 1771.3 182.3 777.7 1044.4 773.2 620.5 212.5 2189.2 701.5 2602.0 60.6 3.4 2121.8 1129.1 4229.7 2158.6 65.7 644.9 2674.7 891.2 126.5 5683.6 209.2 7881.6 25.1 3.9 2085.3 2327.5 306.9 2983.6 993.4 4541.4 183.9 829.4 27.3 1314.8 356.3 729.7 652.9 91.6 360.3 1004.3 50.9 3661.2 1219.5 1527.4 1161.2 HLA-DQA1 "CELIAC1, HLA-DQA" ENSG00000196735 "Major histocompatibility complex, class II, DQ alpha 1" P01909 6 32628179-32647062 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 333.9;lymphoid tissue: 335.8" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 4114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 666.6" "Group enriched" "Detected in all" 19 "B-cells: 287.6;dendritic cells: 666.6;monocytes: 257.6" "Cell line enriched" "Detected in some" 7 "HDLM-2: 1419.1" HPA012315 Enhanced NA NA 200000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA012315: AB_1853930" "unprognostic (4.24e-3)" "unprognostic (1.47e-2)" "unprognostic (1.43e-2)" "unprognostic (7.94e-3)" "unprognostic (1.72e-1)" "unprognostic (6.07e-2)" "unprognostic (3.26e-1)" "unprognostic (5.81e-3)" "unprognostic (2.84e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-2)" "unprognostic (1.15e-1)" "unprognostic (5.36e-2)" "unprognostic (6.74e-2)" "unprognostic (2.27e-1)" "unprognostic (7.43e-2)" "unprognostic (1.57e-1)" 61.7 45.7 2.3 111.0 2.2 7.1 41.6 2.4 2.8 49.9 5.2 76.8 0.1 27.7 32.2 32.1 29.1 127.4 20.8 1.6 5.1 39.6 95.1 333.9 335.8 4.3 2.6 18.6 15.0 2.6 15.2 13.7 2.7 15.1 115.8 1.9 34.8 7.8 7.5 30.0 74.0 19.2 5.4 180.0 103.3 12.2 3.4 234.3 26.0 0.0 322.3 175.9 16.3 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 213.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1419.1 0.9 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 4.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 2.4 0.4 0.0 0.1 0.6 0.6 63.2 1.5 156.1 24.4 0.0 0.0 1.9 105.8 0.5 2.4 257.6 1.0 287.6 3.3 16.5 666.6 274.1 0.4 4.3 3.0 8.2 68.3 162.7 21.6 129.0 2.3 2.2 2.4 2.8 1.6 5.1 4.3 2.6 2.7 5.4 3.4 11.1 67.9 12.8 86.3 0.0 972.8 50.2 0.4 4.3 4.6 0.1 9.8 28.6 2.1 7.2 19.4 0.0 2.1 0.8 179.8 0.9 1.9 4.6 0.6 0.5 0.4 97.4 0.0 38.3 0.1 4.6 2.4 14.7 10.7 0.9 50.4 0.8 12.8 0.6 381.0 0.0 0.1 0.4 2.0 518.6 4114.3 1.3 3.1 874.3 71.2 12.2 957.1 1.0 4.1 0.0 0.2 2.1 0.1 0.0 96.1 1.5 1.8 6.5 27.3 2.5 6.6 1.2 5.3 0.0 0.7 2.5 41.6 2.1 56.0 1.2 2.7 7.6 HLA-DQA2 HLA-DXA ENSG00000237541 "Major histocompatibility complex, class II, DQ alpha 2" P01906 6 32741391-32747198 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.8;lymphoid tissue: 27.1" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 1196.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (4.06e-3)" "unprognostic (2.46e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-2)" "unprognostic (2.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.64e-1)" "unprognostic (2.57e-2)" "unprognostic (8.85e-2)" "unprognostic (4.40e-1)" "unprognostic (1.04e-1)" "unprognostic (7.67e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-2)" "unprognostic (3.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.48e-2)" 10.9 4.5 0.0 0.0 0.0 0.0 7.2 0.0 0.0 3.1 0.0 3.9 0.0 2.1 0.0 3.0 2.8 0.1 2.3 0.0 0.0 5.8 1.7 20.8 0.0 0.0 0.0 0.9 1.2 0.0 2.5 0.0 0.0 2.5 0.0 0.0 3.4 0.0 1.4 8.4 11.6 0.0 0.0 27.1 2.9 0.6 0.0 0.3 3.7 0.0 0.3 3.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.1 3.2 3.6 0.0 179.2 23.5 0.3 1.8 1.2 0.0 2.5 1.3 0.5 0.0 7.5 3.7 0.0 0.2 144.1 0.1 0.0 0.2 0.7 0.1 0.2 20.6 2.4 0.4 0.0 0.0 0.8 1.6 0.0 0.3 0.0 0.8 2.2 0.3 110.0 0.0 0.0 0.0 0.0 78.9 1196.5 2.0 1.2 243.1 24.9 0.0 125.3 0.0 8.2 0.0 0.0 0.2 0.0 0.0 9.5 0.0 0.0 11.2 12.4 0.0 6.6 0.7 1.2 0.1 0.3 0.1 23.3 0.4 13.8 0.0 0.0 0.7 HLF MGC33822 ENSG00000108924 "HLF transcription factor, PAR bZIP family member" Q16534 17 55264960-55325187 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 122.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.7;Excitatory neurons: 77.5;Hepatocytes: 156.8;Horizontal cells: 92.5;Microglial cells: 74.0" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Region enhanced" "Detected in many" "cerebral cortex: 53.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 163.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068156, HPA071210" Enhanced Nucleoplasm Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA068156: AB_2685963, HPA071210: AB_2686361" "unprognostic (1.24e-1)" "unprognostic (1.19e-3)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "prognostic favorable (1.88e-4)" "unprognostic (5.30e-3)" "prognostic favorable (2.71e-7)" "unprognostic (1.42e-1)" "unprognostic (3.44e-2)" "unprognostic (1.24e-3)" "unprognostic (2.19e-1)" "prognostic favorable (3.55e-6)" "unprognostic (8.47e-2)" "unprognostic (1.64e-1)" "unprognostic (6.85e-2)" "unprognostic (1.60e-2)" 15.1 21.5 9.8 1.9 23.1 0.4 15.4 0.0 53.3 14.4 0.0 18.0 1.4 14.4 11.0 26.3 12.2 7.8 24.1 17.6 0.0 12.7 122.4 13.4 2.2 0.0 0.6 50.0 2.9 4.0 9.9 1.0 0.0 13.2 3.4 43.2 24.1 12.4 7.7 16.7 4.3 12.3 0.0 8.2 6.1 4.1 3.9 3.4 34.3 9.9 7.7 12.3 7.8 17.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.9 0.5 0.0 0.0 0.0 0.4 0.2 0.0 27.3 0.7 0.0 0.1 163.0 0.1 0.9 0.2 0.1 0.7 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.6 1.1 0.0 0.1 0.0 2.4 0.0 0.4 0.4 13.0 0.1 11.1 0.6 0.0 7.2 0.2 0.0 0.2 0.0 0.1 0.8 0.2 0.6 0.5 5.1 4.9 0.0 0.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 9.8 23.1 0.0 53.3 17.6 0.0 0.0 0.6 0.0 0.0 3.9 17.2 13.8 3.2 42.8 22.2 0.4 22.3 4.4 1.4 56.9 120.7 5.9 16.4 38.6 12.8 6.3 7.3 10.4 0.1 0.5 0.0 11.7 1.9 1.3 0.1 6.2 19.7 3.0 0.8 77.5 0.9 0.0 17.6 0.0 0.6 0.0 0.5 6.1 156.8 0.1 92.5 36.6 0.6 0.0 3.5 4.0 4.7 28.3 0.7 10.6 74.0 0.1 60.7 0.0 24.6 6.9 0.4 0.0 39.1 1.5 1.3 2.8 23.3 1.0 15.0 13.1 4.5 7.4 0.4 5.0 33.7 27.6 1.2 3.8 0.5 0.4 0.4 HLX "HB24, HLX1" ENSG00000136630 "H2.0 like homeobox" Q14774 1 220879431-220885059 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.5" "Cell type enhanced" "Detected in many" "Adipocytes: 35.7;Endothelial cells: 32.5;Hepatic stellate cells: 47.5;Hofbauer cells: 34.1;Kupffer cells: 24.8;Langerhans cells: 23.5;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 65.1;neutrophil: 55.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 65.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 32.4;THP-1: 100.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005968 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA005968: AB_1079066" "unprognostic (6.18e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.57e-2)" "unprognostic (9.19e-3)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (5.14e-3)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" "unprognostic (3.19e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.28e-6)" "unprognostic (8.44e-3)" "unprognostic (3.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" 35.2 4.7 1.4 10.3 1.3 86.5 18.6 1.4 2.0 7.5 1.5 44.4 4.8 5.5 0.5 3.9 9.3 9.6 18.9 2.0 1.6 6.8 21.8 23.1 8.5 1.9 1.7 4.2 4.3 1.3 3.0 13.8 2.0 6.3 2.0 0.0 3.5 0.4 9.2 8.7 18.9 5.6 1.9 15.7 5.2 1.8 2.6 2.1 9.5 4.2 2.3 11.0 8.8 1.9 0.0 2.1 0.0 3.2 9.2 14.7 3.0 11.4 18.9 12.8 10.6 0.2 0.3 0.0 0.1 6.8 2.5 0.0 0.5 0.0 5.3 3.0 5.9 0.0 1.1 0.3 15.1 3.9 0.8 15.4 0.2 14.7 0.8 1.1 5.7 0.0 4.0 0.0 1.6 0.0 0.0 10.3 0.3 0.0 5.2 0.3 9.0 0.1 0.8 0.1 0.0 2.4 0.7 0.0 32.4 0.1 0.0 100.4 1.8 8.7 0.0 1.3 9.3 0.0 0.0 0.0 14.1 12.3 3.6 65.1 10.4 22.3 0.0 3.4 0.0 5.7 0.0 0.0 13.0 2.7 0.0 0.0 55.9 0.7 0.7 8.7 0.4 3.3 1.4 1.3 1.4 2.0 2.0 1.6 1.9 1.7 2.0 1.9 2.6 1.9 35.7 9.6 5.3 1.0 4.3 2.8 0.1 0.0 0.6 0.1 0.5 1.3 5.7 0.0 0.0 0.0 0.0 0.6 3.0 0.4 0.0 0.5 0.5 0.2 2.6 32.5 0.0 8.4 0.3 0.4 0.7 8.4 0.5 0.3 3.8 0.1 47.5 10.8 34.1 0.0 0.2 0.3 0.0 24.8 23.5 0.4 2.5 17.8 0.0 4.7 44.2 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.2 0.0 0.1 0.0 0.0 6.6 7.5 10.6 0.1 2.2 0.3 3.1 0.4 1.1 0.4 0.3 0.4 HMCES "C3orf37, DC12, SRAPD1" ENSG00000183624 "5-hydroxymethylcytosine binding, ES cell specific" Q96FZ2 3 129278828-129306186 "Predicted intracellular proteins" "DNA damage" "DNA-binding, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 124.9;Spermatocytes: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044968 Enhanced Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA044968: AB_2679160" "unprognostic (9.18e-3)" "unprognostic (1.11e-3)" "unprognostic (4.16e-2)" "unprognostic (2.80e-2)" "unprognostic (2.93e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.41e-4)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (3.00e-1)" "unprognostic (4.12e-3)" "unprognostic (6.32e-2)" "unprognostic (5.46e-2)" "unprognostic (1.71e-2)" "unprognostic (1.74e-1)" "unprognostic (1.25e-2)" "unprognostic (9.08e-3)" 35.8 22.0 27.6 37.3 32.5 37.8 32.9 26.6 32.4 25.8 22.4 36.1 29.4 24.0 23.0 41.7 27.0 21.1 40.3 29.8 30.1 27.4 53.7 27.1 99.7 27.3 27.6 28.3 15.3 68.9 22.2 20.9 27.6 24.6 30.9 27.7 26.8 26.2 57.7 35.5 28.8 23.2 26.4 29.8 26.4 39.9 32.5 57.1 22.4 48.5 131.0 28.5 28.8 27.1 149.4 66.2 74.4 85.9 90.6 37.8 66.8 51.2 41.5 73.1 56.6 105.0 67.9 286.0 53.9 46.9 57.2 106.3 94.8 110.8 83.7 58.0 51.2 59.7 52.7 76.0 38.8 52.1 41.9 36.7 56.6 61.1 60.2 35.6 45.5 63.5 61.2 244.2 40.9 197.3 74.8 45.1 48.4 108.5 42.8 66.6 63.8 50.5 77.0 88.8 74.0 45.6 114.4 70.8 70.6 45.6 121.0 52.1 36.8 36.3 63.7 87.3 66.5 135.8 87.2 289.3 43.4 41.9 41.1 35.5 25.5 65.0 30.4 27.4 31.6 37.5 36.7 36.3 26.3 62.1 36.1 40.0 52.5 27.2 40.9 28.1 48.0 31.2 27.6 32.5 26.6 32.4 29.8 30.1 27.3 27.6 27.6 26.4 32.5 27.1 26.1 32.1 25.6 11.4 23.5 58.2 71.2 72.4 54.7 21.5 18.8 16.1 35.6 30.0 30.4 22.0 10.4 49.2 32.0 30.8 37.2 39.6 8.6 16.0 10.2 27.8 21.0 28.2 13.6 47.0 37.6 23.3 17.9 15.7 22.2 11.0 20.7 26.1 19.7 26.9 14.7 17.3 32.6 8.1 39.4 8.6 24.5 15.7 58.7 10.3 16.4 38.6 25.7 7.1 10.6 33.8 16.9 31.2 124.9 37.3 19.9 21.1 25.2 12.5 13.1 21.0 27.1 127.8 83.6 30.7 43.9 35.0 47.3 23.9 30.7 61.0 HNRNPAB "ABBP1, FLJ40338, HNRPAB" ENSG00000197451 "Heterogeneous nuclear ribonucleoprotein A/B" Q99729 5 178204533-178211163 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046688 Approved Enhanced Nucleoplasm NA NA 460000 "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA046688: AB_10964924" "unprognostic (2.23e-1)" "unprognostic (6.21e-2)" "unprognostic (2.61e-2)" "unprognostic (1.96e-2)" "unprognostic (8.69e-2)" "unprognostic (1.17e-1)" "unprognostic (1.22e-3)" "unprognostic (4.09e-2)" "unprognostic (6.17e-3)" "prognostic favorable (9.79e-4)" "unprognostic (9.12e-3)" "unprognostic (4.23e-2)" "prognostic unfavorable (1.35e-7)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" "unprognostic (3.53e-1)" "unprognostic (2.08e-1)" 86.7 103.2 33.2 92.5 34.9 139.7 63.9 35.6 37.0 66.0 37.3 144.7 98.2 75.5 43.8 122.0 64.4 51.1 83.1 32.4 39.1 91.9 88.3 69.1 95.7 36.9 35.4 56.7 55.4 76.2 46.2 64.0 36.9 59.8 119.0 27.1 68.1 54.0 119.0 115.4 88.9 74.4 35.5 79.9 85.5 38.2 36.9 117.0 52.0 58.7 102.7 122.3 72.7 38.5 347.4 282.5 424.1 414.7 153.8 134.6 613.2 378.5 174.3 296.9 317.2 525.4 251.8 555.2 340.3 204.7 361.1 223.2 373.1 516.7 363.8 865.9 439.5 349.8 223.7 325.1 153.7 446.1 285.6 134.0 239.2 267.3 266.8 122.3 270.3 218.4 290.1 245.7 302.0 934.2 542.6 429.7 389.5 354.0 401.7 436.3 255.6 329.8 254.2 364.8 389.5 302.4 295.2 407.9 278.8 264.0 244.7 270.7 244.0 359.7 305.2 256.2 527.8 285.4 360.2 649.3 145.2 488.2 298.8 3.2 4.4 15.7 5.1 7.0 5.7 5.9 4.1 6.0 4.4 5.2 3.9 4.7 0.8 5.8 7.5 10.9 4.8 2.2 33.2 34.9 35.6 37.0 32.4 39.1 36.9 35.4 36.9 35.5 36.9 38.5 124.7 32.1 41.0 4.6 115.4 281.6 212.1 42.7 243.0 26.5 129.6 141.3 45.9 41.5 42.7 49.7 18.8 106.3 148.5 251.2 50.9 118.9 9.3 112.4 225.6 107.1 119.2 273.2 3.5 151.7 208.9 110.1 167.7 124.7 44.5 102.0 53.6 101.2 101.0 16.8 4.3 219.0 48.8 67.0 129.9 11.1 74.0 109.9 67.6 8.4 56.2 34.7 76.2 3.5 6.1 204.2 138.2 88.0 179.6 275.0 90.5 116.8 25.8 28.3 78.9 149.7 173.6 81.6 122.4 362.5 339.8 114.4 129.7 238.1 247.9 235.5 HNRNPL HNRPL ENSG00000104824 "Heterogeneous nuclear ribonucleoprotein L" P14866 19 38836370-38852347 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016326, HPA051748, HPA052661" Supported Enhanced Nucleoplasm NA NA 420000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB016326: AB_627736, HPA051748: AB_2681588, HPA052661: AB_2681905" "unprognostic (5.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.27e-1)" "unprognostic (9.67e-3)" "unprognostic (8.99e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (3.25e-6)" "unprognostic (1.45e-1)" "unprognostic (8.85e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.57e-2)" "prognostic unfavorable (1.96e-11)" "unprognostic (2.17e-2)" "unprognostic (4.23e-2)" "unprognostic (1.58e-2)" "unprognostic (4.39e-2)" 112.5 108.5 43.8 69.7 46.1 195.1 110.3 49.4 47.4 114.0 42.9 115.2 72.7 119.9 48.0 134.4 97.6 37.4 100.2 41.8 44.5 96.6 98.8 117.7 84.2 47.0 42.9 103.8 87.5 67.7 70.6 57.6 47.5 81.5 76.4 53.2 99.8 45.7 125.7 142.3 113.4 79.9 47.2 113.5 104.3 83.7 46.9 128.8 101.7 57.3 114.5 101.9 111.6 59.4 293.6 214.8 256.4 157.9 94.8 108.7 257.7 233.3 138.9 187.1 177.4 229.9 189.7 436.8 196.2 130.5 152.1 167.0 299.6 228.9 270.7 354.4 231.0 349.9 128.3 205.9 101.2 334.0 228.2 122.7 106.9 187.1 182.1 108.8 209.4 186.7 353.7 200.0 197.6 216.0 347.7 202.9 307.6 186.6 185.6 440.8 296.4 271.7 212.1 203.8 218.6 226.0 225.1 157.7 90.0 172.2 213.4 176.7 207.1 194.9 238.1 184.2 349.4 224.0 312.5 473.1 128.4 293.1 220.0 1.2 1.9 1.2 2.6 3.0 2.0 1.7 2.0 1.7 2.6 2.2 2.0 1.7 1.9 1.8 2.5 5.1 2.6 1.1 43.8 46.1 49.4 47.4 41.8 44.5 47.0 42.9 47.5 47.2 46.9 59.4 62.2 22.4 53.8 40.1 105.1 35.4 52.1 18.0 135.5 76.7 63.6 47.6 22.9 31.5 29.1 22.0 64.6 42.9 100.0 59.0 7.9 37.4 15.9 61.2 64.8 48.7 62.9 83.3 38.0 44.1 35.3 57.0 91.7 88.4 39.3 33.8 43.5 63.0 27.4 33.7 39.0 70.4 12.2 63.7 35.1 11.7 28.3 60.3 26.6 31.9 42.4 39.0 48.4 31.2 56.3 44.1 45.6 22.6 123.0 55.6 55.4 23.9 25.5 78.7 19.7 64.1 59.0 25.5 22.1 117.6 47.5 52.3 95.0 42.4 70.2 41.9 HOMEZ KIAA1443 ENSG00000215271 "Homeobox and leucine zipper encoding" Q8IX15 14 23272422-23299447 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.4" "Group enriched" "Detected in all" 6 "Early spermatids: 309.7;Late spermatids: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036316, HPA036317" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nucleoli" "HPA036316: AB_2675056, HPA036317: AB_10669787" "unprognostic (3.70e-2)" "unprognostic (7.58e-2)" "unprognostic (6.36e-2)" "unprognostic (3.93e-2)" "unprognostic (9.11e-2)" "unprognostic (5.23e-2)" "unprognostic (1.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.37e-1)" "prognostic favorable (2.41e-5)" "unprognostic (2.23e-1)" "unprognostic (1.77e-1)" "prognostic favorable (1.17e-11)" "unprognostic (2.62e-1)" "unprognostic (2.00e-1)" "prognostic favorable (1.75e-4)" "unprognostic (3.23e-1)" 6.1 4.9 4.6 4.7 6.2 1.5 6.7 5.9 5.8 6.5 4.0 6.7 7.3 5.3 8.0 9.8 7.0 5.2 7.8 4.8 5.5 9.4 6.2 6.1 4.6 6.8 5.5 9.9 7.8 8.8 3.6 5.7 6.3 6.5 6.2 6.0 7.0 9.6 9.0 7.7 5.0 7.2 4.9 5.6 7.8 34.4 6.7 9.4 7.3 14.9 7.9 10.9 5.7 6.4 7.0 7.2 13.0 12.3 19.8 8.7 14.8 7.2 9.4 6.8 8.7 3.3 14.6 15.2 6.1 7.1 16.0 23.3 17.3 18.0 8.5 8.4 6.6 5.2 6.0 14.1 25.8 7.6 4.4 13.5 17.7 5.4 11.8 15.1 13.1 17.0 15.6 6.0 11.8 16.1 5.9 5.2 5.3 21.3 4.1 9.2 9.7 6.7 12.5 28.5 4.2 5.2 6.9 19.3 7.8 19.7 12.0 8.9 14.6 4.7 2.1 5.9 3.3 25.1 11.3 5.0 2.5 5.5 7.2 2.9 5.0 7.3 3.5 4.5 2.8 2.6 3.0 2.9 4.8 2.3 3.2 3.9 0.8 2.4 3.4 2.9 4.1 2.9 4.6 6.2 5.9 5.8 4.8 5.5 6.8 5.5 6.3 4.9 6.7 6.4 3.7 6.4 7.0 4.6 5.6 2.8 18.4 19.9 9.1 5.8 7.0 5.7 6.9 12.8 14.4 23.9 6.2 6.9 4.6 6.8 13.7 11.0 309.7 4.4 4.2 5.7 3.6 5.0 1.9 10.9 6.6 5.2 13.7 6.9 3.8 8.2 5.3 6.9 8.7 10.1 2.0 9.2 8.2 6.1 5.1 78.9 6.8 5.8 3.6 6.5 15.1 6.9 5.2 3.0 6.8 9.1 5.5 7.5 6.1 16.3 8.6 19.8 12.9 3.7 6.6 4.7 4.7 15.2 5.3 10.1 5.1 9.3 4.2 3.8 7.9 29.1 HOPX "HOP, LAGY, NECC1, OB1, SMAP31" ENSG00000171476 "HOP homeobox" Q9BPY8 4 56647988-56681899 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 716.7;skin 1: 1439.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 750.0;Alveolar cells type 2: 569.2;Basal keratinocytes: 414.6;dendritic cells: 345.3;NK-cells: 1150.4;Suprabasal keratinocytes: 377.2;Syncytiotrophoblasts: 321.8" "Cancer enhanced" "Detected in many" "glioma: 43.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 518.2;NK-cell: 781.6" "Group enriched" "Detected in all" 15 "NK-cells: 781.6;T-cells: 518.2" "Cell line enhanced" "Detected in many" "HDLM-2: 31.2;HUVEC TERT2: 66.9;RT4: 50.5;TIME: 76.2;U-266/70: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018632, HPA030180" Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear bodies" Cytosol "CAB018632: AB_2120833, HPA030180: AB_10603770" "unprognostic (2.32e-1)" "unprognostic (1.81e-2)" "unprognostic (8.03e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (1.78e-2)" "unprognostic (2.88e-1)" "unprognostic (7.79e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-5)" "unprognostic (3.40e-2)" "unprognostic (1.51e-1)" "unprognostic (7.10e-2)" "unprognostic (5.33e-2)" 9.5 33.7 212.8 27.7 235.6 12.1 112.2 215.4 322.0 250.1 239.2 30.5 17.2 19.1 541.4 716.7 10.5 35.1 48.8 237.4 212.0 24.0 2.9 372.8 18.4 237.6 211.6 9.4 5.3 13.3 11.7 59.6 218.5 26.9 7.0 22.1 172.0 64.7 19.2 1439.9 11.3 115.6 238.8 11.9 33.9 45.3 215.0 15.8 224.5 31.8 190.4 34.1 368.6 234.2 0.0 0.0 0.0 0.0 5.0 15.7 5.9 0.0 0.0 1.4 1.0 0.0 0.0 12.6 0.7 0.3 2.3 2.2 1.4 0.0 1.9 31.2 0.2 0.1 0.0 0.0 2.0 0.0 0.1 2.6 11.9 3.6 0.0 3.4 66.9 0.0 0.0 0.5 3.2 0.5 0.1 1.0 0.1 3.6 0.0 0.0 0.0 0.3 0.0 50.5 1.0 0.6 0.0 0.0 0.0 4.6 0.0 0.0 76.2 0.0 0.2 0.5 0.1 26.0 0.1 0.1 3.2 0.0 0.0 5.7 1.1 2.0 518.2 3.5 282.0 43.4 123.6 227.6 2.6 36.5 20.9 150.8 11.2 781.6 4.5 3.6 9.1 365.6 212.8 235.6 215.4 322.0 237.4 212.0 237.6 211.6 218.5 238.8 215.0 234.2 14.5 750.0 569.2 38.2 23.3 414.6 42.2 8.7 59.7 3.5 3.4 3.0 14.8 2.8 125.6 1.8 0.0 2.3 345.3 0.8 1.9 0.4 33.3 2.8 4.0 28.7 8.4 30.5 62.2 0.2 5.5 16.7 5.6 5.2 10.1 99.5 5.3 1.2 4.0 0.0 7.9 11.1 4.1 11.4 30.9 45.9 3.1 7.9 35.6 14.0 41.4 166.4 1150.4 7.1 6.7 1.7 0.0 3.0 9.6 31.3 1.2 0.6 12.5 5.6 32.9 3.7 104.8 3.3 15.3 31.6 377.2 321.8 219.9 0.1 1.4 28.8 HOXA9 "HOX1, HOX1G" ENSG00000078399 "Homeobox A9" P31269 7 27162438-27175180 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.4;skin 1: 25.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Endometrial stromal cells: 31.1;Enteroendocrine cells: 39.4;Proximal tubular cells: 75.1;Suprabasal keratinocytes: 27.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 6.7;myeloid DC: 5.6;NK-cell: 11.5" "Group enriched" "Detected in many" 6 "dendritic cells: 5.6;granulocytes: 6.7;NK-cells: 11.5" "Cell line enhanced" "Detected in many" "HEK 293: 124.4;PC-3: 43.9;RPTEC TERT1: 42.0;SCLC-21H: 113.4;U-937: 42.3" "Not detected" "Not detected" "HPA061982, HPA076200" Uncertain Enhanced Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA061982: AB_2684651, HPA076200: " "unprognostic (4.72e-1)" "unprognostic (1.23e-2)" "unprognostic (2.86e-1)" "unprognostic (5.24e-3)" "unprognostic (2.36e-1)" "unprognostic (2.02e-1)" "unprognostic (8.35e-2)" "unprognostic (8.44e-3)" "unprognostic (5.50e-2)" "unprognostic (5.71e-2)" "unprognostic (9.87e-3)" "unprognostic (4.42e-2)" "unprognostic (2.80e-3)" "unprognostic (6.45e-2)" "unprognostic (7.58e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" 4.7 5.9 0.0 2.8 0.0 2.5 6.9 0.0 0.2 12.7 0.0 22.0 0.0 17.0 5.6 1.0 19.6 0.0 0.0 0.0 0.0 28.4 0.0 0.4 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.8 0.1 14.1 3.9 0.0 0.0 4.5 16.1 25.7 14.8 1.9 0.2 0.9 0.2 0.0 0.0 1.9 0.1 0.0 0.0 16.8 13.8 0.2 37.7 0.0 0.0 18.4 6.0 4.4 0.0 14.6 11.7 1.2 1.2 2.4 1.4 0.3 1.4 7.9 0.0 34.7 23.5 0.0 1.2 0.0 124.4 0.3 1.1 0.0 0.6 0.0 0.5 6.0 0.0 0.0 0.0 0.0 30.6 0.0 0.0 0.0 1.2 0.0 0.0 1.2 0.0 0.0 43.9 8.1 0.0 0.0 42.0 0.7 113.4 0.0 15.6 0.0 0.3 0.6 0.0 31.3 1.4 0.0 11.4 14.0 0.2 0.0 0.0 0.0 0.0 42.3 0.0 6.7 0.8 0.0 1.3 0.2 0.2 0.1 0.0 0.1 5.6 0.9 0.2 0.0 0.8 11.5 0.3 1.8 0.2 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.2 6.2 0.0 0.0 0.0 2.0 25.1 14.9 0.0 3.4 0.0 12.2 14.7 0.5 0.0 0.0 18.4 0.0 0.2 2.9 10.5 54.8 0.0 0.0 1.0 31.1 4.3 39.4 16.6 0.0 0.0 0.3 4.8 0.0 0.6 0.0 0.0 0.7 0.0 0.3 0.0 0.0 21.7 0.0 3.4 4.2 0.0 0.0 1.9 5.4 0.0 0.8 0.0 2.1 0.0 0.0 0.0 20.2 0.0 0.9 19.4 13.3 75.1 0.0 0.0 0.0 3.0 4.6 0.0 1.0 2.6 27.6 0.3 2.2 0.3 21.4 14.2 HOXB4 "HOX2, HOX2F" ENSG00000182742 "Homeobox B4" P17483 17 48575507-48578350 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 19.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 28.5;Collecting duct cells: 64.4;Glandular and luminal cells: 25.1;Hepatic stellate cells: 24.3;NK-cells: 38.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 30 "medulla oblongata: 11.3;pons: 4.6;spinal cord: 9.1;white matter: 5.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 63.7;HMC-1: 37.5;K-562: 33.7" "Region enriched" "Detected in single" 36 "pons and medulla: 3.5" "Group enriched" "Detected in some" 13 "medulla oblongata: 3.7;spinal cord: 4.7" HPA057432 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Nucleoplasm Centrosome "HPA057432: AB_2683437" "unprognostic (2.71e-2)" "unprognostic (3.87e-2)" "unprognostic (8.97e-3)" "unprognostic (5.39e-3)" "unprognostic (1.14e-2)" "unprognostic (1.66e-1)" "unprognostic (2.65e-2)" "unprognostic (1.59e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (3.22e-2)" "unprognostic (1.14e-1)" "unprognostic (3.41e-1)" "unprognostic (2.10e-1)" "unprognostic (4.85e-2)" "unprognostic (9.25e-3)" "unprognostic (3.41e-3)" 6.9 3.1 0.1 3.7 0.0 0.7 3.5 0.0 0.1 6.8 0.1 9.8 2.6 3.4 19.6 3.4 12.8 3.3 1.0 0.0 0.0 8.7 1.1 4.6 2.3 11.3 0.2 0.3 1.2 4.4 0.0 2.6 4.6 1.0 2.4 0.0 0.3 7.6 2.6 2.5 5.1 4.3 9.1 4.4 4.3 1.2 0.2 1.9 1.0 3.9 1.4 2.9 2.2 5.8 0.3 0.5 0.0 0.2 12.2 9.2 5.2 0.0 0.0 0.8 0.4 6.2 3.1 9.2 63.7 3.3 0.7 0.3 11.8 0.0 0.2 23.3 21.5 21.9 1.6 0.0 12.5 0.0 37.5 10.0 0.0 14.9 0.0 1.2 18.4 14.6 33.7 0.6 15.1 0.0 5.5 0.2 0.0 5.8 0.0 0.0 12.3 4.5 12.5 5.4 0.0 0.0 1.7 0.0 8.7 4.2 0.5 4.3 6.0 0.4 0.5 2.2 0.4 5.0 11.9 2.1 4.3 0.0 5.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 11.3 0.2 4.6 9.1 0.2 5.8 19.9 0.0 0.0 0.0 3.0 3.8 1.3 0.0 28.5 0.0 2.7 1.7 0.9 0.0 0.0 64.4 0.0 23.5 18.4 1.0 11.7 0.2 0.2 18.5 2.7 19.0 0.0 5.0 0.0 0.0 13.1 8.2 0.5 25.1 3.8 0.0 24.3 0.2 4.0 0.0 0.0 2.3 0.0 2.8 4.4 0.2 0.3 2.1 5.4 0.0 1.3 0.0 38.1 0.0 0.0 0.0 1.9 0.0 6.6 0.5 1.0 2.0 0.7 0.0 0.0 5.9 6.4 6.0 23.2 15.5 1.8 6.0 9.9 0.1 1.8 3.1 HOXD4 "HOX4, HOX4B" ENSG00000170166 "Homeobox D4" P09016 2 176151550-176153226 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 24.4;epididymis: 28.0" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Collecting duct cells: 16.5;Early spermatids: 3.7;Endothelial cells: 3.6;Leydig cells: 4.7;Proximal tubular cells: 6.5;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 5.3" "Group enriched" "Detected in many" 21 "medulla oblongata: 10.6;pons: 5.6;spinal cord: 8.1;white matter: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 16.6;HEK 293: 39.7;RPTEC TERT1: 29.6;SK-MEL-30: 11.0" "Region enriched" "Detected in single" 46 "pons and medulla: 4.5" "Group enriched" "Detected in some" 4 "medulla oblongata: 6.0;spinal cord: 7.8" "HPA054383, HPA070349" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Cell Junctions" "HPA054383: AB_2682470, HPA070349: AB_2686258" "unprognostic (9.37e-2)" "unprognostic (1.54e-1)" "unprognostic (1.03e-3)" "unprognostic (1.10e-3)" "unprognostic (9.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.19e-2)" "unprognostic (6.69e-3)" "unprognostic (1.66e-1)" "unprognostic (3.47e-1)" "unprognostic (1.49e-1)" "unprognostic (2.50e-1)" "unprognostic (7.78e-2)" "unprognostic (1.12e-2)" "unprognostic (9.93e-2)" "unprognostic (5.81e-2)" "unprognostic (1.61e-1)" 6.9 8.3 0.0 1.6 0.0 0.0 7.4 0.0 0.1 7.1 0.0 7.3 1.0 24.4 28.0 1.1 14.3 1.5 0.6 0.0 0.0 18.5 0.0 0.4 1.7 10.6 0.3 15.1 0.6 0.1 0.0 0.4 5.6 2.9 2.0 0.0 0.7 11.1 2.8 2.4 6.2 9.7 8.1 7.2 1.0 3.0 0.0 0.2 1.2 0.5 0.4 2.7 4.0 7.3 0.5 0.3 0.0 0.0 2.0 3.0 0.0 0.2 0.9 0.1 1.1 0.9 0.0 0.0 16.6 3.4 0.7 0.2 2.6 0.0 0.4 0.0 39.7 0.5 0.0 0.0 0.5 0.0 0.1 9.3 2.6 0.0 0.5 0.2 6.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 29.6 4.1 2.5 4.2 0.6 0.0 11.0 0.6 0.0 0.0 5.0 0.5 0.2 2.9 2.1 0.0 0.1 0.0 2.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.3 5.6 8.1 0.0 7.3 5.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 3.7 0.1 1.1 3.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.7 2.6 4.7 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 3.0 0.0 0.1 0.3 6.5 0.0 0.0 6.6 0.6 0.9 0.3 0.4 0.0 0.6 0.0 0.1 3.0 1.3 0.0 HOXD8 "HOX4, HOX4E" ENSG00000175879 "Homeobox D8" P13378 2 176129694-176132695 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 99.6;kidney: 76.2" "Cell type enhanced" "Detected in many" "Adipocytes: 51.8;Collecting duct cells: 60.7;Distal tubular cells: 213.2;Early spermatids: 124.6;Leydig cells: 51.3;Peritubular cells: 53.8;Spermatocytes: 82.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "medulla oblongata: 1.5;spinal cord: 4.0;white matter: 5.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 45.4;RPTEC TERT1: 74.8;TIME: 32.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 70 "spinal cord: 34.6" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.22e-1)" "unprognostic (6.31e-2)" "unprognostic (2.19e-3)" "unprognostic (2.68e-2)" "unprognostic (3.35e-1)" "unprognostic (3.49e-1)" "unprognostic (2.56e-3)" "prognostic unfavorable (3.78e-4)" "unprognostic (2.79e-1)" "unprognostic (1.40e-2)" "unprognostic (3.93e-1)" "unprognostic (3.05e-1)" "unprognostic (3.63e-2)" "unprognostic (4.80e-2)" "unprognostic (5.21e-2)" "unprognostic (8.31e-2)" "unprognostic (2.80e-2)" 16.4 20.6 0.0 4.8 0.0 0.0 18.8 0.0 0.0 13.3 0.0 10.8 1.2 19.5 99.6 2.7 17.2 3.1 0.9 0.0 0.0 76.2 0.3 0.9 4.9 1.5 0.0 34.2 1.4 1.1 0.0 0.7 0.8 6.0 4.9 0.0 1.7 24.0 7.8 4.8 8.6 13.1 4.0 10.5 1.6 20.1 0.0 1.0 3.5 1.5 1.3 6.5 9.2 5.8 13.7 2.1 0.0 0.0 8.8 14.1 0.3 1.7 7.2 2.2 0.2 0.1 0.1 0.0 16.7 10.8 1.7 0.1 4.7 0.5 5.4 0.0 6.4 2.3 0.8 0.0 2.9 1.3 0.8 24.7 45.4 0.3 6.7 0.0 22.9 4.4 0.2 0.1 3.7 0.1 0.1 0.4 0.2 0.0 2.6 0.0 4.9 0.2 74.8 9.6 14.2 26.4 4.3 0.0 28.4 1.2 0.0 0.1 32.5 1.1 8.9 15.4 9.1 0.0 0.0 0.0 21.1 0.0 26.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 4.0 0.0 5.8 51.8 0.0 1.1 0.0 0.5 2.7 2.1 0.0 0.6 0.0 0.7 0.6 2.3 0.0 0.0 60.7 0.0 0.0 0.2 2.7 213.2 0.0 124.6 0.7 9.4 36.4 4.8 0.0 0.0 0.0 0.0 14.9 0.0 0.3 0.0 0.0 2.5 0.0 0.1 0.0 0.0 1.8 0.0 0.0 3.4 29.9 51.3 0.5 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 53.8 0.0 1.3 0.5 25.1 0.7 0.0 32.9 14.1 9.8 82.1 20.4 0.2 2.8 0.1 1.0 31.9 3.4 1.1 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 200.5;liver: 866.2;pancreas: 272.1" "Group enriched" "Detected in many" 6 "Hepatocytes: 442.2;Proximal tubular cells: 201.0" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "EFO-21: 31.5;Hep G2: 47.8;T-47d: 22.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 1.8 0.9 5.6 0.2 8.8 0.0 11.6 7.0 7.2 1.6 4.2 1.1 1.4 4.0 3.9 0.3 7.4 4.0 5.1 5.7 6.5 200.5 866.2 11.8 0.4 7.5 8.1 1.3 272.1 24.2 14.8 0.5 7.5 20.1 0.3 0.3 15.6 4.7 22.1 0.9 1.1 0.2 6.5 2.6 58.2 1.3 7.6 0.2 19.9 5.4 0.1 0.6 0.4 11.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.5 0.0 0.1 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.3 0.1 0.0 0.0 3.2 0.2 0.1 0.0 0.2 0.5 22.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.8 7.0 7.2 5.7 6.5 7.5 8.1 7.5 6.5 7.6 11.7 0.5 9.6 32.4 8.8 3.0 0.1 5.1 0.0 0.0 7.2 12.0 8.9 3.4 51.5 1.3 33.1 0.0 0.1 0.0 0.1 52.8 7.5 8.9 4.9 1.0 1.1 2.4 10.7 2.3 26.5 0.3 1.9 18.3 12.5 2.5 0.1 8.6 442.2 1.1 0.0 1.7 2.4 0.0 9.7 0.3 26.0 0.0 1.8 0.0 2.8 0.6 1.6 0.0 0.0 41.6 14.4 0.0 0.4 0.0 7.5 0.0 201.0 0.0 0.6 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.8 1.8 0.1 0.1 0.5 HRH4 "AXOR35, GPCR105, GPRv53, H4R, HH4R" ENSG00000134489 "Histamine receptor H4" Q9H3N8 18 24460637-24479961 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Club cells: 1.3;Early spermatids: 1.2;granulocytes: 1.3;Late spermatids: 1.3;Melanocytes: 1.8;Spermatocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 123 "basophil: 212.9;eosinophil: 61.1" "Lineage enriched" "Detected in many" 191 "granulocytes: 212.9" "Cell line enhanced" "Detected in single" "HL-60: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035009 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA035009: AB_10671507" "unprognostic (1.88e-1)" "unprognostic (2.62e-1)" "unprognostic (4.68e-2)" "unprognostic (9.83e-6)" "unprognostic (1.31e-2)" "unprognostic (3.61e-2)" "unprognostic (1.22e-1)" "unprognostic (8.96e-2)" "unprognostic (2.20e-1)" "unprognostic (3.30e-1)" "unprognostic (7.25e-2)" "unprognostic (2.91e-1)" "unprognostic (6.65e-7)" "unprognostic (1.89e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-4)" "unprognostic (7.70e-2)" 0.1 0.1 0.2 0.4 0.1 0.8 0.0 0.3 0.3 0.1 0.3 0.1 0.5 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.3 0.6 0.5 0.1 0.0 0.3 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.2 0.0 1.3 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.1 212.9 0.1 61.1 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.2 0.5 0.5 0.2 0.1 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.3 0.2 0.0 0.6 0.3 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.3 0.4 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.3 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.7 1.3 0.0 0.1 1.8 1.0 0.0 0.3 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.0 0.8 0.3 1.3 0.3 0.0 0.6 0.0 0.5 0.2 0.0 0.4 HS3ST6 HS3ST5 ENSG00000162040 "Heparan sulfate-glucosamine 3-sulfotransferase 6" Q96QI5 16 1911475-1918415 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 75.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 10.7;Horizontal cells: 21.9;Suprabasal keratinocytes: 9.1;Urothelial cells: 24.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "A549: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.72e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-1)" "unprognostic (4.99e-3)" "unprognostic (2.10e-2)" "unprognostic (6.55e-3)" "unprognostic (2.42e-1)" "unprognostic (3.61e-1)" "unprognostic (2.26e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.5 0.0 0.0 0.0 14.4 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 1.4 0.0 0.0 1.9 0.0 0.3 75.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 4.1 10.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 3.4 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.7 1.8 0.0 0.2 0.0 6.3 0.0 0.0 4.5 10.7 0.5 0.1 0.0 0.0 0.1 0.0 0.4 2.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 21.9 0.1 0.9 4.1 0.0 1.5 1.4 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.0 0.0 2.7 0.2 0.2 5.0 0.2 0.0 0.0 0.3 0.0 0.0 4.5 9.1 0.1 0.1 0.0 1.7 24.9 HSD17B8 "D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1" ENSG00000204228 "Hydroxysteroid 17-beta dehydrogenase 8" Q92506 6 33204655-33206831 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 125.2;Proximal tubular cells: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 79.5;T-47d: 62.0;U-266/70: 65.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042132 Enhanced NA NA 97000 "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA042132: AB_10793978" "prognostic favorable (9.99e-4)" "unprognostic (4.24e-1)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (2.10e-1)" "unprognostic (8.11e-2)" "prognostic favorable (1.90e-5)" "unprognostic (1.50e-3)" "unprognostic (3.12e-1)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" "prognostic favorable (2.18e-12)" "unprognostic (2.82e-2)" "unprognostic (5.57e-1)" "unprognostic (3.09e-1)" "unprognostic (3.23e-2)" 9.6 24.6 10.1 6.5 10.5 9.7 17.0 9.9 11.3 13.7 10.9 18.0 19.7 7.2 29.4 25.5 23.6 7.9 20.3 9.6 10.8 30.7 67.4 11.2 10.5 11.3 11.9 8.6 55.3 42.2 14.1 5.6 12.3 11.3 16.2 11.8 25.1 16.5 20.8 25.9 18.8 7.3 11.4 12.1 15.1 5.9 10.8 13.3 32.9 25.0 15.1 9.8 12.8 11.3 7.0 15.0 6.8 9.3 2.3 4.4 1.3 0.8 4.7 0.1 0.1 5.8 17.5 45.4 11.2 1.2 2.2 29.1 7.2 11.7 1.0 8.6 0.0 2.6 14.0 27.1 20.0 0.0 3.8 5.0 28.9 0.2 49.4 0.4 2.1 13.6 0.3 46.2 4.1 9.4 31.2 1.3 2.1 23.3 2.9 11.0 1.2 79.5 27.8 1.3 12.1 7.6 2.9 34.3 7.6 4.6 62.0 1.8 1.3 0.7 7.3 0.6 0.4 65.5 42.4 16.6 3.1 1.0 1.7 0.1 5.8 2.0 18.7 13.4 30.0 16.6 24.0 29.2 11.6 13.1 26.4 28.5 0.7 16.8 14.6 20.8 21.8 26.7 10.1 10.5 9.9 11.3 9.6 10.8 11.3 11.9 12.3 11.4 10.8 11.3 12.5 19.2 21.6 3.3 18.6 29.7 28.3 55.0 21.6 12.4 31.3 34.8 31.8 48.6 25.9 22.0 6.2 29.9 9.7 21.2 125.2 27.9 6.3 20.0 6.0 10.1 18.0 12.8 0.3 32.4 12.9 9.1 16.3 13.7 7.0 9.8 10.0 83.2 17.4 1.7 0.5 26.6 20.3 10.3 16.4 18.1 7.5 7.9 49.8 1.0 8.1 32.6 6.2 1.0 0.7 21.9 21.1 6.0 47.6 15.4 74.8 137.2 33.3 14.8 0.0 11.3 9.8 8.1 8.5 40.0 37.2 17.4 18.0 29.8 44.4 31.5 HSF2BP MEILB2 ENSG00000160207 "Heat shock transcription factor 2 binding protein" O75031 21 43529186-43659488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "testis: 24.1" "Group enriched" "Detected in many" 7 "Early spermatids: 125.5;Late spermatids: 49.0;Spermatocytes: 132.4;Spermatogonia: 63.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 12.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031724, HPA075775" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Cytosol "HPA031724: AB_10601022, HPA075775: " "unprognostic (1.91e-2)" "unprognostic (1.19e-1)" "unprognostic (7.27e-3)" "unprognostic (1.54e-4)" "unprognostic (2.62e-1)" "unprognostic (1.78e-2)" "unprognostic (9.36e-4)" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (4.55e-2)" "unprognostic (1.79e-1)" "unprognostic (3.11e-1)" "unprognostic (1.44e-2)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (8.77e-4)" "unprognostic (6.00e-2)" 0.3 0.3 0.4 0.1 0.5 0.1 0.5 0.3 0.9 0.5 0.3 0.3 0.2 0.6 0.5 0.3 0.6 0.2 0.4 1.3 0.7 0.5 0.2 0.2 0.3 0.5 0.5 0.7 0.2 0.8 0.8 0.9 0.6 0.4 0.2 0.9 0.4 0.4 0.2 0.4 0.2 0.2 0.3 0.2 0.2 24.1 0.7 0.1 0.5 0.1 0.2 0.3 0.4 0.7 4.6 0.9 1.2 0.5 0.2 1.1 1.1 1.6 0.9 1.6 1.4 6.1 4.5 3.5 2.4 0.9 5.7 1.8 0.6 12.8 0.5 0.9 1.1 0.6 1.9 0.3 1.4 1.5 0.4 0.7 8.2 0.7 3.8 7.5 0.4 2.0 1.3 1.1 3.9 0.8 2.0 1.4 3.9 1.1 1.9 2.9 1.2 0.5 2.0 0.8 1.3 1.0 3.3 1.6 1.7 0.5 1.7 1.7 2.6 0.9 3.0 0.2 2.4 1.2 0.9 2.8 0.8 3.0 2.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.3 0.0 0.3 0.7 0.7 0.0 0.4 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.9 1.3 0.7 0.5 0.5 0.6 0.3 0.7 0.7 0.2 0.0 0.0 2.6 0.1 0.9 1.5 4.7 2.8 1.0 1.3 1.7 0.7 0.0 2.0 0.0 0.0 1.8 0.2 0.2 0.0 1.1 125.5 0.5 1.4 0.5 0.0 0.0 3.0 0.2 2.8 2.1 0.0 0.4 0.0 2.4 0.4 0.3 0.7 0.0 1.7 0.1 0.0 0.0 0.7 49.0 1.8 0.5 0.0 0.0 0.0 2.1 0.0 3.0 4.4 2.7 0.3 1.5 0.0 0.8 0.0 1.1 2.8 2.5 13.1 0.5 0.9 132.4 63.1 0.6 0.4 0.8 0.2 3.8 0.3 1.0 HYAL4 ENSG00000106302 "Hyaluronidase 4" Q2M3T9 7 123828983-123877481 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 4.0;skeletal muscle: 3.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.8;Cytotrophoblasts: 4.3;Extravillous trophoblasts: 8.1;Spermatogonia: 4.4;Syncytiotrophoblasts: 2.2" "Cancer enriched" "Detected in single" 48 "testis cancer: 8.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;CAPAN-2: 5.9;RT4: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA029453 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA029453: AB_10601432" "unprognostic (5.19e-5)" "unprognostic (4.18e-2)" "unprognostic (4.82e-2)" "unprognostic (2.20e-1)" "unprognostic (4.14e-2)" "unprognostic (2.60e-1)" "unprognostic (8.24e-2)" "unprognostic (5.26e-2)" "unprognostic (8.15e-3)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (5.55e-3)" 0.1 0.1 0.6 0.0 0.7 0.5 0.1 1.0 1.0 0.1 0.5 0.2 0.0 0.1 0.4 0.4 0.0 0.1 0.2 0.7 0.4 0.4 0.1 0.4 0.2 0.5 0.3 0.2 0.5 0.0 0.0 4.0 0.7 0.2 0.1 1.0 0.5 0.2 3.9 0.9 0.2 0.0 0.1 0.8 0.2 2.1 0.5 0.0 0.4 0.0 1.0 0.2 0.0 1.3 0.2 0.4 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 5.9 0.2 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.1 0.0 13.9 0.2 0.0 0.0 0.8 0.0 1.1 0.2 0.0 2.0 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.6 0.2 0.1 0.1 0.0 0.0 0.6 0.7 1.0 1.0 0.7 0.4 0.5 0.3 0.7 0.1 0.5 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 8.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 1.3 4.4 0.0 0.0 2.2 0.0 0.0 0.0 0.2 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 12 "T-cells: 81.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Group enriched" "Detected in some" 8 "HEL: 4.6;MOLT-4: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" 0.5 0.1 0.0 7.7 0.0 16.5 0.3 0.0 0.0 0.2 0.0 0.7 0.7 0.2 0.1 0.5 0.3 1.4 0.2 0.0 0.0 0.2 0.4 2.6 14.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.2 2.3 0.4 0.0 3.3 1.3 0.2 0.0 20.2 0.4 0.0 16.2 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.2 0.0 15.1 6.8 0.0 0.0 15.7 7.2 0.1 0.5 0.0 0.0 29.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.3 0.0 3.1 2.9 0.0 0.0 0.0 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.2 6.3 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.8 4.7 0.1 0.0 3.1 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.0 1.8 0.1 81.2 0.0 0.0 0.1 IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574096 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Secreted in other tissues" NA NA 310000 "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA063478: AB_2685020" "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favorable (3.69e-4)" "prognostic favorable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" 6.7 10.1 3.4 2.8 3.6 3.5 6.1 3.7 4.2 8.1 5.9 8.6 3.3 7.4 9.7 9.8 6.5 2.9 11.7 3.4 3.7 5.9 11.4 5.9 3.4 3.8 3.7 5.4 12.3 9.5 4.7 2.7 3.9 9.1 3.8 10.3 7.8 4.2 28.8 36.4 6.8 3.7 3.6 6.3 8.2 25.8 3.6 2.4 6.7 9.7 4.1 8.9 7.9 3.8 12.1 22.9 6.2 15.1 10.5 5.8 8.5 10.4 13.3 6.1 5.2 19.4 9.5 12.5 16.4 14.3 7.2 16.3 14.6 10.0 3.9 14.7 8.8 5.1 13.7 25.9 11.5 14.9 6.5 5.4 6.6 9.1 14.0 7.8 8.6 3.3 10.0 8.1 5.4 18.0 6.6 8.8 10.2 10.4 5.2 10.2 10.8 9.0 10.9 19.3 2.2 5.6 14.3 6.4 6.7 6.8 12.6 6.3 15.3 4.4 8.2 5.0 10.4 11.2 12.2 14.5 6.9 10.9 4.4 0.3 3.5 1.4 2.0 4.2 2.2 2.9 2.6 2.9 4.6 2.1 1.9 2.0 0.0 3.7 5.9 1.3 3.9 2.3 3.4 3.6 3.7 4.2 3.4 3.7 3.8 3.7 3.9 3.6 3.6 3.8 12.9 9.6 14.1 20.9 11.1 5.2 6.1 10.5 5.2 15.0 8.7 4.3 45.7 7.2 10.6 7.3 47.9 11.2 10.0 14.0 1.9 14.0 46.4 14.9 19.3 10.8 10.8 19.6 43.3 20.2 5.7 9.1 22.4 16.5 1.3 9.9 11.7 24.1 11.9 6.7 42.6 12.7 18.3 16.6 5.4 12.0 6.5 12.5 8.8 23.4 7.8 7.8 4.1 20.6 24.0 16.5 5.7 10.1 24.2 12.2 9.0 10.7 23.3 26.9 6.6 7.6 13.2 51.5 11.0 19.6 16.3 3.8 8.5 9.8 9.8 9.6 IFNLR1 "CRF2/12, IFNLR, IL-28R1, IL28RA" ENSG00000185436 "Interferon lambda receptor 1" Q8IU57 1 24154168-24187959 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 17.4;Proximal enterocytes: 18.2;Urothelial cells: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "memory B-cell: 4.9;naive B-cell: 5.9;plasmacytoid DC: 11.3" "Group enriched" "Detected in many" 5 "B-cells: 5.9;dendritic cells: 11.3" "Cell line enhanced" "Detected in many" "U-266/70: 51.4;U-266/84: 19.4;U-698: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017319 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA017319: AB_1851708" "prognostic favorable (5.12e-4)" "unprognostic (7.16e-2)" "unprognostic (8.61e-3)" "unprognostic (8.48e-2)" "unprognostic (8.09e-2)" "unprognostic (1.22e-2)" "unprognostic (7.28e-3)" "unprognostic (2.33e-1)" "unprognostic (5.10e-2)" "unprognostic (1.93e-1)" "unprognostic (5.51e-2)" "unprognostic (4.50e-1)" "unprognostic (3.66e-3)" "unprognostic (5.15e-2)" "unprognostic (1.69e-1)" "unprognostic (2.69e-1)" "unprognostic (1.10e-1)" 0.4 2.2 1.1 2.8 1.2 0.6 2.6 6.2 1.1 1.7 2.2 3.8 5.8 0.9 1.9 3.6 1.8 2.1 3.1 0.8 2.6 3.0 8.4 2.9 7.8 2.5 2.2 1.3 5.0 5.2 5.9 0.3 2.5 3.4 4.0 1.8 4.5 2.1 3.6 7.3 9.2 0.4 1.9 2.8 2.9 1.0 2.7 1.4 4.4 1.3 9.7 2.1 2.3 2.7 6.7 1.3 0.0 0.0 0.0 0.0 1.6 0.0 0.6 1.2 1.0 11.3 1.9 14.3 15.1 0.0 5.4 5.0 6.6 11.6 0.9 3.0 3.5 0.0 2.3 3.4 0.0 0.0 0.0 0.0 3.8 0.3 3.5 2.5 0.0 2.9 0.3 0.0 0.0 1.6 0.2 0.4 14.0 0.5 4.1 0.1 0.0 1.2 2.6 2.8 2.0 1.3 3.5 2.0 1.4 2.4 2.7 0.1 0.0 0.0 2.7 0.0 0.1 51.4 19.4 40.8 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 4.9 0.3 1.4 0.0 5.9 0.5 1.4 0.0 0.0 0.0 11.3 0.3 0.5 1.1 1.2 6.2 1.1 0.8 2.6 2.5 2.2 2.5 1.9 2.7 2.7 0.5 0.0 4.8 2.3 5.9 11.1 10.0 4.1 12.5 3.4 1.4 3.2 3.5 2.8 2.3 1.8 0.0 0.6 5.3 17.4 3.9 2.9 2.2 3.4 0.2 0.5 0.0 0.0 2.2 2.3 1.0 0.8 3.1 2.7 0.0 1.5 0.0 8.4 2.3 0.0 2.8 4.1 0.0 0.8 1.9 4.3 0.3 3.0 0.0 2.8 5.5 2.9 0.0 0.5 0.1 2.4 6.1 0.0 12.5 4.3 18.2 2.3 5.1 2.3 0.0 0.0 0.6 0.0 0.7 8.3 12.6 0.3 2.2 0.1 3.3 17.2 IGDCC4 "LOC57722, NOPE" ENSG00000103742 "Immunoglobulin superfamily DCC subclass member 4" Q8TDY8 15 65381484-65422947 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;skeletal muscle: 10.6;tongue: 14.0" "Cell type enhanced" "Detected in many" "Astrocytes: 18.6;Cone photoreceptor cells: 31.3;Fibroblasts: 14.7;Leydig cells: 34.8;Microglial cells: 14.0;Oligodendrocyte precursor cells: 17.6;Skeletal myocytes: 29.8" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.4;AF22: 9.4;CAPAN-2: 8.1;EFO-21: 4.5;HSkMC: 5.2;NTERA-2: 7.2;SuSa: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008510, HPA008576" Approved Approved Approved Nucleoplasm,Cytosol NA NA 64000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA008510: , HPA008576: AB_1079496" "unprognostic (1.16e-1)" "unprognostic (9.38e-2)" "unprognostic (1.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.58e-1)" "unprognostic (1.77e-2)" "unprognostic (2.75e-3)" "unprognostic (9.94e-2)" "unprognostic (4.18e-2)" "unprognostic (3.65e-2)" "unprognostic (3.29e-2)" "unprognostic (6.36e-2)" "unprognostic (1.83e-8)" "unprognostic (3.30e-2)" "unprognostic (4.54e-2)" "unprognostic (2.33e-1)" "unprognostic (5.32e-3)" 0.9 2.5 5.6 2.4 6.9 0.0 0.5 5.8 2.5 3.4 0.0 0.8 0.5 1.4 4.2 1.6 1.7 4.2 0.9 2.9 7.2 0.1 0.0 0.2 0.6 11.2 9.4 8.5 0.1 0.3 0.9 5.6 6.8 0.4 0.6 0.8 0.5 0.4 10.6 0.8 0.8 1.0 6.9 0.2 1.1 0.6 11.3 0.7 1.9 14.0 0.6 2.1 2.0 4.5 0.0 4.4 9.4 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.3 0.5 8.1 0.0 4.5 0.3 0.0 0.0 2.3 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.3 0.0 0.0 5.2 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.8 7.2 0.0 0.0 0.0 2.3 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.4 5.4 0.0 0.0 0.0 3.7 2.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 6.9 5.8 2.5 2.9 7.2 11.2 9.4 6.8 6.9 11.3 4.5 0.2 0.0 0.0 18.6 0.0 2.3 0.0 0.0 0.0 7.7 0.2 0.5 2.2 0.0 0.0 3.7 31.3 0.4 0.1 0.0 0.0 0.4 0.4 0.0 2.1 0.3 0.0 0.0 0.9 0.0 0.6 14.7 1.1 0.0 0.0 8.8 0.0 0.0 0.7 0.0 6.3 0.0 0.0 0.0 2.5 1.4 34.8 0.3 5.4 14.0 0.0 1.0 1.0 17.6 1.0 0.3 0.0 4.1 0.1 0.1 0.0 0.7 0.0 12.2 6.6 29.8 1.0 0.8 2.6 0.1 1.1 0.8 0.3 7.0 0.0 0.0 IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 580.8;Fibroblasts: 1360.5;Leydig cells: 1030.8;Peritubular cells: 1495.9;Sertoli cells: 1170.1;Smooth muscle cells: 420.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 1163.6;BJ: 476.9;BJ hTERT+: 683.3;fHDF/TERT166: 1045.9;hTERT-RPE1: 468.5;U-87 MG: 631.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" 145.8 90.2 28.1 9.2 32.6 0.4 150.5 31.8 40.8 276.6 71.6 75.5 20.8 117.2 129.5 75.8 237.4 36.8 107.0 28.4 33.1 30.6 7.7 40.4 8.7 32.7 29.2 136.8 15.9 4.8 106.3 15.7 33.2 129.3 28.0 6.6 35.9 122.2 38.5 39.2 52.5 39.0 36.7 45.2 67.6 22.2 41.7 6.8 58.4 102.2 9.2 127.1 214.1 27.2 135.3 219.6 0.2 177.3 313.9 1163.6 0.8 476.9 683.3 126.9 69.0 23.2 294.7 0.0 68.5 1045.9 96.4 453.3 3.0 42.3 26.2 1.2 2.8 4.4 37.1 33.3 111.9 0.8 1.1 325.5 2.3 57.4 11.9 468.5 30.5 7.5 0.6 9.3 53.1 0.5 6.6 1.0 6.8 4.1 150.4 2.3 4.9 5.6 10.1 3.3 1.3 8.7 152.2 0.0 10.9 4.0 6.3 0.5 132.2 87.2 41.2 95.5 18.0 5.3 10.7 0.6 631.6 6.7 49.5 0.0 0.0 31.6 0.6 6.8 3.4 0.1 1.0 5.4 2.1 0.0 0.5 6.8 0.0 0.0 20.1 0.0 0.0 1.5 28.1 32.6 31.8 40.8 28.4 33.1 32.7 29.2 33.2 36.7 41.7 27.2 83.9 6.4 4.2 2.0 3.4 113.6 41.0 580.8 23.9 2.5 5.9 29.0 21.1 10.0 37.6 20.2 0.0 3.0 3.5 0.2 11.7 87.9 9.6 4.9 99.2 71.9 0.0 3.2 3.1 8.0 4.9 1360.5 30.5 2.5 0.0 2.3 116.4 0.8 7.6 0.0 3.6 0.3 50.8 6.8 122.8 32.6 1030.8 15.2 144.1 19.7 2.5 51.1 0.0 1.5 0.9 77.1 0.0 1495.9 9.6 94.9 0.0 15.2 13.9 2.8 1170.1 102.3 420.9 3.8 6.8 8.0 87.8 3.4 14.1 0.4 0.0 34.1 IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11451.9;urinary bladder: 3998.0" "Group enriched" "Detected in many" 16 "B-cells: 3900.5;Plasma cells: 9883.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.7" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 766.8" "Lineage enriched" "Detected in many" 123 "B-cells: 766.8" "Group enriched" "Detected in many" 9 "Karpas-707: 157.8;U-698: 392.7" "HPA001245, CAB008642" Supported "Immunoglobulin genes" NA NA 230000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" 526.0 696.8 0.7 1661.1 0.6 681.1 203.2 0.5 4.5 518.2 2.8 302.1 103.7 210.6 18.4 334.4 661.5 312.9 143.2 0.4 2.2 491.7 356.1 962.4 3281.1 4.7 3.2 407.0 38.5 7.9 35.8 2.3 2.3 209.8 85.1 0.3 391.6 250.8 13.1 28.5 1008.8 27.6 12.7 11451.9 608.9 172.8 1.2 1773.7 1277.9 0.1 5826.8 3998.0 267.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.7 0.0 0.0 2.3 0.0 0.0 0.0 8.4 0.0 5.3 0.0 0.0 0.0 22.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 157.8 0.0 0.0 1.7 2.1 2.6 0.0 0.0 2.9 15.1 3.7 0.0 0.0 18.2 17.0 3.1 0.0 0.0 0.0 0.0 0.2 10.8 0.0 3.2 3.3 4.5 4.9 0.3 392.7 0.1 3.7 0.0 0.2 0.3 0.1 0.3 0.0 0.2 766.8 0.6 0.3 0.4 134.9 0.0 0.1 6.2 0.1 0.1 0.1 0.2 96.2 0.7 0.6 0.5 4.5 0.4 2.2 4.7 3.2 2.3 12.7 1.2 1.8 2.9 73.7 378.5 0.0 3900.5 0.0 8.1 0.0 0.0 0.0 0.5 0.0 2.8 22.8 9.3 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.5 0.0 0.1 8.5 13.9 83.4 0.0 0.0 0.0 13.6 8.2 0.0 209.4 0.0 46.1 52.9 0.1 0.0 0.0 5.0 0.0 62.8 0.0 0.9 0.0 9.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 5.4 0.0 9883.3 9.1 0.0 10.9 1.5 0.1 0.0 0.0 1.5 1.9 1.0 0.0 0.0 0.0 415.6 0.0 13.6 0.1 IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 4319.4" "Group enriched" "Detected in some" 8 "B-cells: 2050.1;Plasma cells: 2918.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 447 "memory B-cell: 339.0;naive B-cell: 119.3" "Lineage enriched" "Detected in single" 661 "B-cells: 339.0" "Group enriched" "Detected in some" 4 "RH-30: 9.6;RPMI-8226: 25.1" HPA001245 Approved "Immunoglobulin genes" NA NA 250000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "prognostic favorable (3.53e-4)" "unprognostic (6.88e-3)" "unprognostic (2.40e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "prognostic favorable (3.30e-6)" "unprognostic (1.06e-1)" "unprognostic (6.67e-2)" "unprognostic (1.74e-1)" "unprognostic (7.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (4.72e-2)" "unprognostic (3.32e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-2)" 109.5 11.0 1.3 170.0 1.4 34.8 56.0 0.2 4.1 59.9 0.8 202.8 7.5 55.8 0.8 90.2 51.5 20.7 15.2 0.2 1.1 157.5 98.2 171.0 65.4 0.9 0.2 16.3 8.0 0.1 8.2 0.0 0.5 64.2 9.4 0.0 201.2 1.2 3.5 13.3 330.7 1.0 1.5 4319.4 87.2 2.3 0.3 16.7 134.4 0.0 226.0 100.4 104.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 25.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 339.0 0.5 0.0 0.3 119.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 34.5 1.3 1.4 0.2 4.1 0.2 1.1 0.9 0.2 0.5 1.5 0.3 1.8 0.2 54.5 305.3 0.0 2050.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 2.8 13.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.2 4.1 0.0 32.5 0.0 0.0 0.0 3.1 0.0 0.0 126.1 0.0 8.2 5.1 0.1 0.0 0.0 0.9 0.0 12.4 0.0 0.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2918.6 0.7 0.0 3.5 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.1 305.5 0.0 0.7 0.0 IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 354.8;lymphoid tissue: 414.0;salivary gland: 120.1;stomach 1: 305.5" "Cell type enriched" "Detected in single" 18 "Plasma cells: 1.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.9" "Group enriched" "Detected in some" 72 "memory B-cell: 276.3;naive B-cell: 180.8;plasmacytoid DC: 99.0" "Group enriched" "Detected in many" 73 "B-cells: 276.3;dendritic cells: 99.0" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.7;U-698: 1.8" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.28e-3)" "unprognostic (2.05e-2)" "unprognostic (6.81e-2)" "unprognostic (9.53e-2)" "prognostic favorable (3.55e-4)" "unprognostic (2.51e-1)" "unprognostic (2.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" 8.6 5.3 0.1 196.9 0.1 35.6 72.8 0.0 1.9 18.6 0.2 260.2 354.8 3.3 0.0 15.7 5.2 12.6 1.4 0.1 0.1 2.3 6.1 28.5 46.8 1.3 0.0 8.2 3.1 0.4 0.0 0.7 0.5 4.3 182.6 0.0 120.1 0.5 0.0 0.0 171.1 12.0 0.3 100.2 305.5 1.0 0.2 14.6 2.9 0.0 414.0 61.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.2 276.3 0.6 2.5 0.2 180.8 0.3 0.3 0.0 0.1 0.1 99.0 0.2 29.1 0.1 0.1 0.0 1.9 0.1 0.1 1.3 0.0 0.5 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHM ENSG00000211899 "Immunoglobulin heavy constant mu" P01871 14 105851705-105856218 "Disease related genes, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 1315.0;lymphoid tissue: 4112.3" "Group enriched" "Detected in many" 14 "B-cells: 3757.1;Plasma cells: 9906.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 16 "memory B-cell: 4278.4;naive B-cell: 6731.2" "Lineage enriched" "Detected in all" 19 "B-cells: 6731.2" "Group enriched" "Detected in many" 9 "Daudi: 4983.6;U-698: 4905.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" CAB008643 Uncertain "Immunoglobulin genes" NA NA 110000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008643: AB_1617732" "unprognostic (2.91e-3)" "prognostic favorable (6.49e-4)" "unprognostic (9.30e-3)" "unprognostic (9.90e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.70e-6)" "unprognostic (9.61e-3)" "unprognostic (1.01e-1)" "unprognostic (1.52e-2)" "unprognostic (3.23e-3)" "unprognostic (2.46e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (3.01e-1)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (6.28e-3)" 52.0 9.0 0.4 373.7 0.4 395.3 56.6 0.2 1.7 67.9 1.8 446.8 1204.9 11.1 10.2 66.8 38.5 141.7 50.5 0.2 0.4 48.4 84.7 180.6 3192.1 1.9 0.3 9.7 44.5 0.6 8.7 3.6 0.7 15.1 201.4 0.0 325.1 6.1 2.7 1.7 1315.0 7.9 1.0 4112.3 528.9 70.9 0.7 117.3 37.0 0.7 497.1 128.0 10.5 0.5 4.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 4983.6 2.9 0.0 0.0 0.8 0.0 0.0 0.0 21.6 0.0 3.0 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 1.7 28.7 1.2 0.0 0.0 580.2 2.2 6.9 0.0 0.0 4.0 5.8 3.0 0.5 1.2 0.0 0.2 3.8 6.5 0.0 13.8 1.2 2.5 1.5 1.5 4905.9 0.0 2.4 0.0 10.8 5.4 5.6 3.1 1.2 2.3 4278.4 5.5 6.8 5.4 6731.2 4.5 3.8 25.4 11.4 4.5 346.1 11.4 815.2 0.4 0.4 0.2 1.7 0.2 0.4 1.9 0.3 0.7 1.0 0.7 0.5 1.0 38.5 254.5 0.0 3757.1 0.0 0.2 0.0 1.2 0.0 2.2 0.8 0.3 31.5 14.2 0.0 0.0 0.0 63.8 1.8 0.0 0.0 0.0 0.0 0.1 4.2 6.7 474.1 0.0 0.0 0.0 10.8 27.5 0.0 152.6 0.0 56.7 147.9 0.1 0.0 0.0 2.2 0.0 158.1 0.0 0.0 0.0 12.4 0.0 0.0 5.2 0.0 11.3 0.0 0.0 0.0 1.2 0.0 9906.5 0.3 0.0 2.2 1.5 0.0 0.0 0.4 16.8 0.0 0.0 0.2 0.0 0.0 415.0 0.3 4.1 0.1 IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.5;lymphoid tissue: 129.5;stomach 1: 43.3" "Cell type enriched" "Detected in some" 22 "Plasma cells: 176.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 99 "memory B-cell: 54.7;naive B-cell: 52.7" "Lineage enriched" "Detected in single" 101 "B-cells: 54.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" 2.9 0.8 0.0 37.1 0.0 7.9 15.5 0.0 0.1 4.7 0.0 66.5 81.5 1.0 0.3 4.1 1.9 6.7 1.4 0.0 0.0 1.8 2.8 7.7 38.5 0.1 0.0 3.2 1.3 0.1 0.1 0.0 0.0 1.1 74.0 0.0 32.2 1.9 0.0 0.3 33.9 2.3 0.0 66.9 43.3 1.6 0.0 8.2 4.6 0.0 129.5 10.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 54.7 0.0 0.0 0.0 52.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.3;intestine: 59.5;urinary bladder: 103.9" "Cell type enriched" "Detected in some" 107 "Plasma cells: 958.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "memory B-cell: 39.7" "Lineage enriched" "Detected in single" 137 "B-cells: 39.7" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;U-2 OS: 2.3" "Immunoglobulin genes" NA NA 7200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" 3.8 0.9 0.0 0.0 0.1 11.1 3.9 0.0 0.4 15.3 0.3 59.5 0.0 1.4 1.2 27.0 3.2 47.3 0.3 0.0 0.0 1.3 3.5 13.1 41.1 0.2 0.0 5.6 0.4 0.0 0.1 0.0 0.0 3.9 32.3 0.0 16.1 5.7 0.0 1.5 10.1 1.3 0.0 31.8 6.3 0.6 0.0 0.0 2.5 0.0 39.7 103.9 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 39.7 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 958.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 175 "Plasma cells: 2295.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" 13.0 2.1 0.3 0.0 0.1 0.0 7.5 0.0 0.4 4.2 0.2 441.3 0.0 1.2 0.0 17.9 4.3 1.5 2.7 0.0 0.1 3.2 6.2 13.6 0.0 0.3 0.1 0.9 11.5 0.0 0.3 0.0 0.1 1.6 0.0 0.0 56.7 8.6 0.1 2.0 40.9 11.2 0.3 159.0 19.5 0.3 0.2 0.0 6.8 0.0 0.0 3.7 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.1 19.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.1 0.3 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2295.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 40 "Plasma cells: 622.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" 2.1 2.5 0.0 13.5 0.0 7.1 6.7 0.0 0.1 2.0 0.0 29.7 12.0 1.3 0.0 2.9 1.4 5.4 1.5 0.0 0.0 3.3 2.1 4.8 13.7 0.0 0.0 0.5 0.9 0.0 0.1 0.0 0.0 1.4 19.3 0.0 21.2 0.7 0.0 0.1 13.9 0.6 0.0 51.3 18.6 0.3 0.0 7.0 3.3 0.0 55.0 41.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 131.0 0.0 0.4 0.1 136.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 622.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.6;lymphoid tissue: 47.5;salivary gland: 34.6" "Cell type enriched" "Detected in some" 178 "Plasma cells: 232.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 13.0;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 35 "B-cells: 13.0" "Cell line enhanced" "Detected in single" "RH-30: 2.2" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" 1.7 0.3 0.0 9.6 0.0 0.9 7.6 0.0 0.2 3.0 0.0 26.6 1.6 1.3 0.0 2.2 1.8 0.0 0.3 0.0 0.0 1.7 1.0 11.6 12.5 0.1 0.0 0.2 0.4 0.0 0.2 0.1 0.1 1.1 9.1 0.0 34.6 0.3 0.1 0.2 22.7 5.5 0.0 47.5 9.5 0.2 0.0 1.3 4.0 0.0 9.4 2.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.1 12.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 622 "Plasma cells: 3673.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HL-60: 2.6;SiHa: 1.7" HPA047702 Approved "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" 3.1 4.4 0.1 93.5 0.4 11.1 17.1 0.1 0.5 5.9 0.3 111.6 63.0 1.0 0.0 16.4 5.2 10.1 2.3 0.1 0.2 3.6 2.0 18.0 43.6 0.4 0.2 17.9 4.0 0.3 0.1 0.0 0.2 1.7 126.7 0.0 54.1 1.1 0.1 0.6 46.7 4.3 0.3 56.3 87.4 0.2 0.1 13.0 4.5 0.0 203.0 58.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.6 0.0 0.6 0.0 0.1 0.8 0.0 0.0 0.0 0.0 181.1 0.0 0.0 0.1 155.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 27.5 0.1 0.4 0.1 0.5 0.1 0.2 0.4 0.2 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3673.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGSF5 JAM4 ENSG00000183067 "Immunoglobulin superfamily member 5" Q9NSI5 21 39745407-39802096 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 8 "Syncytiotrophoblasts: 114.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 5.8" HPA057282 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Focal adhesion sites" "HPA057282: AB_2683395" "unprognostic (1.06e-1)" "unprognostic (2.53e-1)" "unprognostic (7.06e-2)" "unprognostic (9.73e-5)" "unprognostic (1.56e-2)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.18e-2)" "unprognostic (2.09e-1)" "unprognostic (8.35e-2)" "unprognostic (9.61e-2)" "unprognostic (4.01e-1)" "unprognostic (4.18e-1)" "unprognostic (3.75e-2)" "unprognostic (6.89e-2)" "unprognostic (1.07e-2)" 0.3 1.2 2.0 0.2 2.8 0.4 0.9 0.6 1.9 0.7 2.4 0.4 0.3 0.7 1.9 0.2 0.7 0.4 3.3 1.5 2.6 0.4 0.4 0.3 0.4 1.5 1.6 1.0 1.5 0.2 0.6 2.5 1.3 1.4 0.7 1.2 0.5 0.4 0.2 0.5 0.3 0.4 0.7 0.4 0.5 1.1 3.6 0.6 0.6 0.1 0.4 0.4 0.1 1.4 0.7 0.4 2.4 0.6 2.3 1.8 0.6 0.4 0.6 0.6 1.0 0.4 0.7 0.8 0.6 0.9 0.9 0.6 0.8 1.6 1.3 1.3 1.1 0.7 1.9 0.3 1.4 1.0 0.3 1.7 2.9 1.5 1.7 1.2 0.3 0.3 1.4 0.5 0.9 0.9 0.2 0.3 1.3 0.6 0.4 0.4 1.1 0.4 1.0 1.0 1.1 0.3 0.6 1.6 1.0 1.0 5.8 0.6 0.2 1.0 1.2 0.5 1.0 0.5 0.4 0.5 0.6 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.0 2.8 0.6 1.9 1.5 2.6 1.5 1.6 1.3 0.7 3.6 1.4 0.0 0.0 0.0 8.5 0.0 0.0 0.2 0.0 0.0 1.2 1.0 0.8 9.7 0.0 0.1 1.8 0.0 1.6 0.0 0.6 5.9 0.6 12.8 0.0 0.4 0.2 0.0 0.0 2.9 0.2 1.7 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 4.1 0.4 0.0 0.0 0.0 4.8 0.3 0.1 0.0 0.0 0.0 1.0 0.0 5.0 1.0 0.2 0.2 0.4 0.0 1.4 0.0 6.8 0.1 0.2 0.0 0.0 0.2 0.5 0.2 0.0 0.0 114.1 0.1 1.1 0.4 2.0 IGSF6 DORA ENSG00000140749 "Immunoglobulin superfamily member 6" O95976 16 21639550-21652608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.8" "Group enriched" "Detected in many" 13 "Hofbauer cells: 216.2;Kupffer cells: 246.9;Langerhans cells: 132.6;Macrophages: 327.1;monocytes: 179.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 1213.7" "Lineage enhanced" "Detected in all" "granulocytes: 1213.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041023, HPA041072" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA041023: AB_10794434, HPA041072: AB_10794262" "unprognostic (7.94e-2)" "prognostic favorable (4.92e-4)" "unprognostic (1.18e-2)" "prognostic favorable (1.54e-5)" "unprognostic (3.27e-1)" "unprognostic (4.03e-2)" "unprognostic (2.31e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-2)" "unprognostic (6.76e-2)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (8.12e-2)" "unprognostic (1.81e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-1)" "unprognostic (2.02e-1)" 2.6 2.3 0.5 13.4 0.6 1.7 1.2 0.8 1.0 1.0 0.7 5.1 1.7 0.4 0.2 0.6 1.1 0.3 0.7 0.6 0.5 0.8 5.5 7.4 3.9 1.0 0.7 0.4 0.9 0.7 0.5 3.3 0.9 0.9 1.5 0.2 2.0 1.6 0.2 0.5 2.7 0.5 0.5 29.8 1.3 0.2 0.6 2.2 0.6 0.9 1.2 2.3 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.5 303.9 46.2 0.7 357.2 0.8 3.8 0.5 0.9 233.9 0.5 0.9 1.2 1213.7 2.7 263.5 55.5 1.0 210.7 0.5 0.6 0.8 1.0 0.6 0.5 1.0 0.7 0.9 0.5 0.6 1.4 1.7 3.2 12.2 0.7 7.1 3.2 0.7 0.0 0.0 1.3 1.4 3.7 4.0 2.8 5.0 1.8 10.4 0.7 15.2 0.0 0.0 0.2 0.4 1.0 1.2 4.0 0.0 6.5 1.1 0.0 1.4 3.2 0.0 2.5 10.1 0.4 2.9 1.8 216.2 0.0 0.8 0.3 0.0 246.9 132.6 0.1 0.9 327.1 8.8 16.9 179.9 0.7 3.1 1.0 0.4 0.0 1.2 0.0 1.3 0.6 0.1 0.4 4.4 2.1 0.0 0.9 1.1 0.1 0.2 0.6 2.0 1.4 5.4 0.2 0.0 0.5 IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 47.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB025983: , HPA015788: AB_1851566" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.76e-2)" "unprognostic (7.78e-3)" "unprognostic (7.37e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.34e-7)" "unprognostic (1.48e-2)" "unprognostic (5.77e-2)" "unprognostic (2.84e-3)" "unprognostic (2.84e-2)" 2.4 3.7 2.6 16.7 4.6 8.7 3.1 2.0 3.2 4.1 1.9 7.8 7.4 1.7 3.9 14.6 2.8 5.1 1.4 2.7 3.3 3.4 1.6 4.1 24.3 4.1 3.6 1.2 3.4 1.0 1.9 2.6 3.9 3.6 7.7 0.1 6.9 2.1 0.5 15.0 8.0 2.5 2.7 14.2 7.2 0.7 4.4 16.5 4.5 0.3 20.4 8.4 6.8 4.6 17.8 13.9 3.7 0.4 6.7 9.2 3.9 7.1 22.3 9.4 10.4 11.5 26.9 35.3 18.6 14.5 11.5 23.0 0.1 18.1 2.2 5.5 3.5 4.7 8.8 7.6 8.4 29.5 14.8 12.2 3.2 7.7 1.7 10.9 14.2 9.4 2.3 10.0 10.5 3.6 19.2 47.7 5.2 4.3 10.9 9.7 4.3 27.7 10.7 29.4 0.0 0.0 2.9 22.9 4.2 4.5 13.8 20.3 26.5 9.0 5.5 6.9 8.5 3.5 1.8 23.3 17.1 24.2 3.7 12.2 32.8 0.6 21.2 23.3 14.8 26.4 32.4 30.1 9.5 14.0 25.7 27.3 2.2 23.9 13.4 3.2 52.8 28.6 2.6 4.6 2.0 3.2 2.7 3.3 4.1 3.6 3.9 2.7 4.4 4.6 0.4 0.0 4.5 0.7 13.7 1.9 3.6 37.8 1.8 0.0 4.3 3.7 0.9 4.3 16.3 0.0 0.0 4.2 7.9 11.7 0.0 12.1 3.3 1.5 0.9 0.7 3.6 4.4 1.5 12.6 5.2 3.4 17.3 2.4 5.1 3.7 2.2 0.8 13.8 0.0 1.5 6.4 8.2 12.9 0.7 7.0 0.9 16.0 7.2 1.9 9.0 0.0 14.4 1.0 0.2 15.9 21.5 0.7 6.4 3.2 10.7 3.5 14.5 0.0 0.0 0.7 3.1 0.3 0.9 11.1 4.8 1.5 15.8 3.9 10.2 11.6 IKZF1 "hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1" ENSG00000185811 "IKAROS family zinc finger 1" Q13422 7 50304068-50405101 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "bone marrow: 173.0;lymphoid tissue: 112.5" "Cell type enhanced" "Detected in many" "B-cells: 120.5;dendritic cells: 221.4;Erythroid cells: 89.8;Microglial cells: 91.8;monocytes: 106.6;NK-cells: 150.4;Plasma cells: 128.9;T-cells: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 140.4;HDLM-2: 258.6;HMC-1: 220.4;JURKAT: 128.9;MOLT-4: 184.3;REH: 192.3;U-698: 342.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009247, HPA035221, HPA035222" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB009247: AB_2124699, HPA035221: AB_2674524, HPA035222: AB_2674525" "prognostic favorable (4.28e-4)" "prognostic favorable (2.02e-4)" "unprognostic (2.49e-3)" "unprognostic (2.41e-3)" "unprognostic (5.59e-1)" "prognostic favorable (8.63e-4)" "unprognostic (1.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-2)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-2)" "unprognostic (6.77e-2)" "unprognostic (4.67e-2)" 5.0 3.2 3.5 53.0 3.4 173.0 4.4 4.0 3.9 3.6 3.3 7.6 7.0 2.5 2.3 4.8 2.2 7.7 1.5 3.0 4.0 1.4 4.9 11.6 87.1 7.7 5.2 1.6 0.8 0.8 0.6 3.6 7.5 2.3 6.8 0.2 4.6 1.9 1.0 2.0 15.6 4.0 7.3 48.6 12.0 1.7 8.7 112.5 2.1 1.2 73.8 9.6 1.8 10.3 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 258.6 0.2 52.1 0.0 0.0 0.0 84.5 220.4 0.0 0.0 0.0 0.0 0.0 0.0 128.9 72.4 15.4 0.0 0.0 184.3 80.9 2.4 0.0 0.0 192.3 0.3 39.6 0.0 0.0 1.6 2.0 0.8 1.0 0.8 0.4 0.2 112.1 0.2 0.0 1.9 0.2 0.4 80.8 49.4 342.7 0.5 89.5 0.5 21.2 14.2 25.0 35.4 43.9 29.1 46.7 36.3 35.0 15.1 40.7 48.2 35.7 20.2 24.3 43.3 23.4 32.6 26.4 3.5 3.4 4.0 3.9 3.0 4.0 7.7 5.2 7.5 7.3 8.7 10.3 2.8 3.2 12.2 0.7 120.5 2.8 0.1 0.0 0.0 0.0 2.8 1.9 1.5 2.8 1.8 1.8 0.0 0.4 221.4 0.3 0.0 0.4 3.8 0.5 0.4 2.6 0.0 89.8 0.2 0.0 0.4 2.5 4.6 0.6 23.4 0.2 3.9 2.0 30.6 0.0 0.3 0.0 0.0 64.3 61.0 5.3 0.0 72.1 19.6 91.8 106.6 0.0 150.4 1.0 0.3 0.1 0.4 0.0 128.9 0.1 0.0 1.0 1.5 0.1 0.0 1.5 1.6 0.1 2.1 0.5 2.7 0.7 182.8 0.1 0.1 0.1 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.6;lymphoid tissue: 73.7" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Extravillous trophoblasts: 93.0;Kupffer cells: 190.7;Langerhans cells: 145.0;Macrophages: 128.6;monocytes: 175.7;NK-cells: 110.2;Plasma cells: 129.5;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.5;HDLM-2: 76.6;Karpas-707: 27.7;RPMI-8226: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 13.9 8.9 4.7 39.8 4.9 63.6 6.1 4.4 7.0 5.6 4.9 12.0 8.0 3.5 2.7 6.4 5.2 17.9 5.3 4.2 5.9 4.1 13.1 23.8 51.7 6.9 5.1 3.1 2.4 2.6 3.6 14.2 5.5 4.7 14.5 0.5 5.2 3.2 1.7 3.2 24.8 10.4 6.0 73.7 9.2 1.9 5.3 16.9 4.2 3.3 32.4 20.7 3.7 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 0.2 0.0 0.7 0.0 0.5 0.0 0.0 76.6 0.0 0.2 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.6 27.7 0.0 0.0 0.4 6.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 5.6 1.0 8.0 0.0 11.4 0.0 3.3 48.9 2.4 52.8 68.6 38.3 12.6 51.0 62.1 44.7 6.2 17.9 33.3 3.4 70.2 58.6 17.3 88.7 84.1 4.7 4.9 4.4 7.0 4.2 5.9 6.9 5.1 5.5 6.0 5.3 7.5 2.2 6.4 16.0 0.3 52.8 5.7 0.4 0.0 5.7 0.1 1.0 1.9 2.7 0.0 1.3 0.0 0.0 1.3 87.5 0.5 0.0 0.2 0.1 0.4 0.5 4.9 0.0 9.3 0.8 0.8 93.0 2.3 6.6 0.7 12.6 0.0 3.6 1.4 60.4 0.0 1.2 0.0 0.0 190.7 145.0 0.5 0.3 128.6 17.8 22.5 175.7 0.4 110.2 0.0 0.6 0.1 0.1 0.0 129.5 0.0 0.0 1.0 1.5 0.1 0.0 1.6 2.7 0.1 0.3 1.2 4.1 3.3 105.5 0.0 0.7 0.4 IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Kupffer cells: 13.9;NK-cells: 69.0;Plasma cells: 15.3;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 18.8;HDLM-2: 35.2;Karpas-707: 57.8;U-698: 15.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" 2.1 1.2 1.0 15.2 1.8 9.3 0.9 1.0 2.1 1.0 1.7 3.1 4.5 0.7 0.8 1.6 0.8 3.5 0.7 1.1 1.1 0.9 2.2 5.8 24.6 2.5 1.5 0.6 0.5 1.3 0.5 1.6 2.3 0.8 2.9 0.5 1.7 0.6 0.7 1.6 7.0 1.9 1.1 16.2 4.1 0.8 2.3 6.6 0.7 0.2 14.1 4.0 0.5 3.7 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.1 0.5 1.0 0.3 2.2 18.8 0.1 0.2 0.7 0.3 0.0 0.0 0.0 35.2 0.2 2.2 0.6 0.3 1.0 0.9 3.1 0.1 0.0 0.5 0.0 0.2 0.1 5.1 0.3 57.8 0.0 0.2 9.7 0.3 0.1 0.1 0.0 6.7 0.1 0.8 0.0 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.4 9.7 0.4 0.5 0.4 0.2 0.2 6.6 11.0 15.2 0.6 12.1 1.1 8.5 12.5 9.2 50.9 34.7 64.0 11.5 34.8 41.7 14.7 9.1 19.3 34.0 14.7 40.9 34.0 8.1 53.0 24.3 1.0 1.8 1.0 2.1 1.1 1.1 2.5 1.5 2.3 1.1 2.3 3.7 0.5 0.0 3.0 0.3 9.6 0.3 2.1 0.1 0.6 0.0 0.3 0.5 1.0 1.5 0.6 0.0 0.0 0.2 35.1 0.1 0.0 0.0 0.5 0.5 0.2 0.5 0.0 5.2 0.8 0.0 0.8 0.7 3.1 0.7 4.5 0.0 0.4 0.1 6.4 0.0 0.4 0.0 0.0 13.9 4.0 0.0 0.0 11.7 0.0 3.7 11.9 0.0 69.0 0.0 2.6 0.1 0.0 0.0 15.3 0.5 0.4 0.2 0.2 0.0 0.0 0.7 0.3 0.4 0.1 0.0 0.9 0.1 31.5 0.0 0.2 1.3 IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115694 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.9;Kupffer cells: 81.4;Macrophages: 61.4;monocytes: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HL-60: 59.9;NB-4: 52.5;THP-1: 74.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 62000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.92e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (9.83e-2)" "unprognostic (7.66e-2)" "unprognostic (5.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.96e-2)" "prognostic favorable (8.35e-4)" "unprognostic (2.16e-2)" "unprognostic (1.27e-1)" "unprognostic (6.51e-3)" 9.1 5.6 5.5 9.6 11.3 31.8 6.9 5.7 7.5 5.4 6.8 4.7 3.8 5.4 5.0 5.2 6.0 3.6 4.6 6.3 5.5 3.7 5.7 10.0 6.9 9.8 7.3 4.5 5.2 3.9 3.8 3.5 8.9 5.0 3.4 1.5 5.2 2.8 1.8 6.9 6.2 5.3 7.7 16.6 5.6 2.0 7.7 15.4 4.2 2.6 5.6 4.6 4.7 9.6 7.9 4.5 4.1 5.1 8.0 4.6 5.1 11.5 7.4 5.3 6.8 4.4 5.1 7.1 4.6 11.6 6.9 12.4 5.6 5.4 3.7 11.6 6.6 0.0 2.6 2.8 9.2 59.9 17.8 6.8 7.9 4.7 3.7 5.2 5.7 5.6 3.0 7.3 5.5 6.7 7.2 52.5 2.2 10.1 4.3 1.6 0.8 1.3 5.1 5.8 2.8 0.1 8.0 6.7 5.7 4.6 5.3 74.7 15.9 4.1 5.8 6.1 4.3 5.8 3.4 3.3 6.0 28.3 4.5 8.5 7.4 7.2 1.1 3.4 0.9 0.5 1.5 1.2 3.9 0.4 2.4 1.8 16.5 1.5 3.5 1.8 1.0 2.6 5.5 11.3 5.7 7.5 6.3 5.5 9.8 7.3 8.9 7.7 7.7 9.6 14.0 12.8 14.1 2.9 13.8 8.8 6.6 10.2 10.8 3.9 7.2 5.8 6.1 10.0 8.6 5.5 8.4 6.1 18.7 23.6 0.0 8.7 4.0 7.2 8.1 13.7 13.2 9.2 8.3 12.6 11.9 13.6 29.0 9.7 7.6 58.9 17.5 11.1 34.0 3.3 6.4 13.9 6.1 81.4 16.2 2.1 9.0 61.4 8.8 41.2 114.2 4.3 28.8 12.5 11.4 12.2 12.4 4.5 10.3 9.1 14.7 3.4 8.0 2.9 13.1 10.4 10.0 3.0 13.4 9.0 6.8 6.4 25.4 8.1 12.4 9.6 IL20RB "DIRS1, FNDC6, IL-20R2, MGC34923" ENSG00000174564 "Interleukin 20 receptor subunit beta" Q6UXL0 3 136946230-137011085 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 110.7;skin 1: 163.3;vagina: 66.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 36.8;Basal respiratory cells: 115.8;Basal squamous epithelial cells: 60.9;Club cells: 43.0;Early spermatids: 57.0;Late spermatids: 28.8;Squamous epithelial cells: 56.5;Suprabasal keratinocytes: 38.1" "Group enriched" "Detected in many" 5 "cervical cancer: 54.5;head and neck cancer: 50.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 86.0;HBEC3-KT: 140.0;HHSteC: 91.8;hTCEpi: 555.6;hTERT-HME1: 102.6" "Not detected" "Not detected" HPA063914 Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Cytosol "HPA063914: AB_2732709" "unprognostic (1.35e-2)" "unprognostic (1.05e-1)" "unprognostic (7.43e-4)" "unprognostic (2.48e-4)" "unprognostic (2.74e-1)" "unprognostic (3.31e-1)" "unprognostic (7.43e-4)" "unprognostic (4.08e-3)" "unprognostic (7.64e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (3.57e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.55e-1)" "unprognostic (3.55e-2)" "unprognostic (1.33e-2)" "unprognostic (5.57e-2)" 2.3 0.2 0.1 0.0 0.2 0.0 10.3 0.1 0.6 24.3 0.1 0.6 0.0 0.2 0.0 110.7 0.4 0.0 0.6 0.1 0.1 0.2 5.4 0.5 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.4 0.2 2.2 0.5 0.0 13.6 0.2 1.0 163.3 0.4 0.0 0.1 0.3 0.5 3.7 0.2 2.0 0.5 0.9 9.5 1.3 66.2 0.2 27.2 0.0 0.1 0.4 15.4 64.9 2.6 0.6 1.8 0.3 1.2 2.7 3.4 0.2 14.9 9.7 1.0 86.0 0.0 140.0 0.7 0.4 0.0 0.3 19.5 0.0 91.8 0.2 0.2 11.5 555.6 4.5 102.6 0.7 0.1 0.1 0.3 0.1 0.0 0.0 0.6 0.0 0.4 2.4 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.0 54.6 0.0 2.8 4.7 0.5 0.9 0.0 0.2 1.8 0.5 0.5 0.1 0.2 0.2 8.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.7 0.0 0.0 0.7 0.0 36.8 1.7 115.8 60.9 0.0 0.3 0.5 0.4 0.0 43.0 0.0 0.0 1.7 0.8 0.8 0.0 0.9 57.0 0.7 0.4 0.9 0.0 0.0 1.0 0.2 1.4 3.9 0.0 0.8 0.0 0.2 0.0 2.2 0.4 0.0 1.2 0.7 10.2 0.3 6.6 28.8 0.3 0.6 3.6 1.0 1.7 0.0 1.0 1.0 0.2 1.0 0.1 0.7 0.4 1.3 0.2 0.3 5.5 0.0 0.0 0.6 3.6 1.7 1.9 56.5 38.1 1.6 0.6 0.2 0.5 5.3 IL36G "IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1" ENSG00000136688 "Interleukin 36 gamma" Q9NZH8 2 112973203-112985658 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 14.3;lymphoid tissue: 39.4;skin 1: 31.3" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 136.0;Club cells: 36.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 36.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.1;HaCaT: 1.0" "Not detected" "Not detected" HPA068168 Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Nucleoplasm, Plasma membrane" "HPA068168: " "unprognostic (1.56e-2)" "unprognostic (2.88e-1)" "unprognostic (7.27e-2)" "unprognostic (3.15e-2)" "unprognostic (4.91e-2)" "unprognostic (1.92e-1)" "unprognostic (3.68e-1)" "unprognostic (3.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (5.79e-2)" "unprognostic (5.58e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 3.9 0.2 0.0 31.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 39.4 0.8 3.6 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 136.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.7 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 3.9 0.0 0.0 0.0 1.3 0.2 0.0 1.7 13.2 0.0 0.0 0.0 0.0 7.8 IL5RA "CD125, CDw125, IL5R" ENSG00000091181 "Interleukin 5 receptor subunit alpha" Q01344 3 3066324-3126613 "CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.0;fallopian tube: 10.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 28.0;granulocytes: 19.0;Plasma cells: 9.9;Respiratory ciliated cells: 13.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 192 "basophil: 178.4;eosinophil: 355.1" "Lineage enriched" "Detected in many" 255 "granulocytes: 355.1" "Cell line enriched" "Detected in some" 28 "HMC-1: 71.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 910000 "Cluster 2: Granulocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.38e-3)" "unprognostic (2.26e-2)" "unprognostic (2.66e-1)" "unprognostic (6.13e-3)" "unprognostic (2.66e-1)" "unprognostic (1.54e-3)" "unprognostic (7.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.83e-1)" "unprognostic (1.67e-1)" "unprognostic (9.84e-4)" "unprognostic (4.32e-3)" "unprognostic (3.08e-2)" "unprognostic (6.95e-2)" "unprognostic (2.20e-1)" "unprognostic (7.49e-2)" "unprognostic (4.93e-2)" 0.2 0.2 0.8 0.6 0.7 0.6 1.0 0.6 0.3 1.0 9.0 0.7 1.7 0.4 0.2 0.5 10.7 0.7 1.0 0.8 1.2 0.4 0.1 2.7 0.4 5.0 4.6 0.1 0.4 0.0 1.5 0.1 3.2 1.8 1.1 0.0 0.7 0.1 0.4 0.1 1.6 0.3 4.5 1.8 1.1 1.1 1.2 0.5 0.2 0.0 1.5 1.7 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 2.5 71.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 178.4 0.1 355.1 0.9 0.1 0.1 0.4 1.0 0.7 0.1 1.3 0.3 0.7 1.0 0.0 0.1 0.1 0.1 0.7 0.8 0.7 0.6 0.3 0.8 1.2 5.0 4.6 3.2 4.5 1.2 0.9 0.2 0.0 2.5 0.0 4.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 2.3 1.5 1.4 0.0 0.0 0.1 2.8 0.0 0.0 0.0 2.4 28.0 0.3 0.1 0.0 0.8 0.7 0.0 0.0 0.2 0.0 0.5 19.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.0 0.3 5.7 0.0 0.1 5.4 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 9.9 0.8 0.0 0.1 13.9 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.1 IL7R "CD127, IL7RA" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.7" "Group enriched" "Detected in many" 4 "monocytes: 271.8;T-cells: 973.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2" "Group enriched" "Detected in all" 33 "NK-cells: 113.2;T-cells: 369.5" "Cell line enhanced" "Detected in many" "BJ: 99.8;BJ hTERT+ SV40 Large T+: 87.7;fHDF/TERT166: 187.7;HBF TERT88: 168.3;REH: 406.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" NA NA 610000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" 11.2 14.4 1.5 137.6 1.8 14.0 20.4 7.4 2.7 12.0 1.0 17.3 15.0 3.9 1.6 11.0 5.7 32.4 2.2 2.0 2.5 4.5 12.5 63.9 139.4 1.8 0.5 2.2 5.3 0.8 1.7 2.9 1.6 8.7 20.4 0.9 3.3 3.1 4.1 3.8 56.8 5.6 0.6 70.1 34.1 4.7 4.4 183.7 7.6 1.7 123.0 48.0 7.1 6.2 0.6 0.4 0.7 0.4 0.7 0.6 0.6 99.8 50.6 87.7 51.3 0.5 0.6 9.6 0.3 187.7 15.9 16.0 0.2 6.0 168.3 8.6 1.1 3.2 10.3 0.0 1.5 0.6 7.2 1.6 0.0 18.7 4.3 2.4 2.6 0.7 0.7 0.9 71.3 0.2 2.3 1.0 0.3 0.3 4.6 406.2 5.2 0.6 0.0 5.3 0.4 0.2 15.9 1.7 0.2 0.3 0.6 0.4 7.0 34.5 58.4 14.8 13.4 0.6 0.2 10.4 17.4 9.2 27.8 4.3 1.6 1.0 102.1 1.2 369.5 1.5 213.8 151.1 0.7 2.1 179.5 124.6 7.3 113.2 1.5 1.8 39.7 87.7 1.5 1.8 7.4 2.7 2.0 2.5 1.8 0.5 1.6 0.6 4.4 6.2 8.9 16.0 16.0 0.0 47.4 11.6 2.7 0.0 5.2 0.0 8.6 6.1 4.9 0.0 2.5 0.0 0.0 0.2 136.0 0.6 0.0 1.0 0.1 1.1 0.4 13.2 0.0 16.4 0.0 2.0 0.2 11.6 53.5 1.2 19.6 0.2 13.2 4.4 10.6 0.0 0.0 0.5 0.0 10.6 98.5 0.8 0.0 58.8 21.4 2.8 271.8 0.0 11.3 0.0 0.0 0.1 1.4 0.0 93.5 1.4 0.0 0.8 5.8 0.0 0.0 5.5 7.9 0.2 0.1 1.5 10.4 0.3 973.8 0.4 0.4 3.5 IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030877 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 359.1;skeletal muscle: 257.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 440.3;Extravillous trophoblasts: 272.2;Proximal tubular cells: 498.6;Squamous epithelial cells: 202.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 26.0;neutrophil: 31.3" "Group enriched" "Detected in many" 11 "dendritic cells: 9.0;granulocytes: 31.3;monocytes: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 258.2;OE19: 299.8;SiHa: 155.1" "Low region specificity" "Detected in all" HPA029561 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Mitochondria "HPA029561: AB_10601932" "unprognostic (1.16e-1)" "unprognostic (1.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.50e-2)" "unprognostic (4.25e-2)" "unprognostic (3.25e-3)" "unprognostic (4.26e-3)" "unprognostic (4.08e-2)" "unprognostic (1.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.56e-2)" "unprognostic (4.24e-3)" "prognostic favorable (0.00e+0)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (3.35e-2)" 19.8 11.1 2.5 12.3 3.2 31.5 14.8 1.8 4.4 31.0 5.3 50.0 22.4 16.2 1.7 131.2 16.3 19.9 29.5 2.5 2.4 129.4 47.4 23.2 5.7 2.2 2.4 7.8 359.1 5.3 11.1 22.0 2.1 13.7 30.7 0.8 31.0 5.9 257.1 150.0 29.2 15.6 2.3 19.0 53.7 2.9 2.6 5.0 17.4 89.8 7.3 61.0 50.8 2.3 29.3 41.7 11.3 20.4 14.1 10.5 258.2 7.2 18.4 2.9 4.2 35.4 21.7 6.1 17.4 10.1 24.1 19.8 13.2 6.9 0.8 33.5 22.5 0.0 56.0 30.6 8.3 47.5 2.3 23.9 36.3 10.0 5.2 8.5 3.9 30.7 7.4 0.0 10.7 31.8 19.4 27.1 40.5 299.8 42.7 36.0 29.6 28.6 122.1 15.6 15.0 0.3 155.1 35.8 16.2 14.5 33.3 58.5 0.0 5.6 11.5 73.7 7.3 24.5 66.3 17.9 24.0 31.7 9.6 9.4 11.4 26.0 0.7 8.7 0.3 1.5 0.7 0.2 9.0 0.3 0.3 0.5 31.3 0.1 5.8 6.7 1.1 3.1 2.5 3.2 1.8 4.4 2.5 2.4 2.2 2.4 2.1 2.3 2.6 2.3 9.2 19.2 32.7 17.6 7.8 105.5 22.7 32.1 159.4 0.7 16.8 20.2 11.6 72.9 16.1 22.0 0.0 52.5 5.8 72.9 440.3 83.4 2.8 5.7 20.2 6.9 17.5 15.3 4.7 110.6 272.2 16.1 65.2 30.4 2.5 13.4 10.0 66.8 42.5 0.0 1.8 90.2 65.1 37.7 17.0 7.1 4.7 34.2 14.2 5.6 25.5 22.3 2.1 0.5 0.5 56.1 50.1 3.8 8.6 42.9 36.9 498.6 12.3 1.0 105.2 16.0 27.6 0.8 10.1 202.1 141.4 106.3 6.1 14.0 84.4 52.8 INO80C "C18orf37, FLJ38183, hIes6, IES6" ENSG00000153391 "INO80 complex subunit C" Q6PI98 18 35452230-35497979 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 184.7;Pancreatic endocrine cells: 165.1;Spermatocytes: 209.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049060 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center" "HPA049060: AB_2680617" "unprognostic (3.40e-1)" "prognostic favorable (3.58e-4)" "unprognostic (2.29e-1)" "prognostic unfavorable (2.62e-5)" "unprognostic (5.56e-2)" "unprognostic (9.68e-2)" "unprognostic (1.72e-3)" "unprognostic (2.03e-1)" "unprognostic (3.32e-3)" "unprognostic (2.08e-3)" "unprognostic (2.61e-1)" "unprognostic (6.94e-3)" "unprognostic (1.18e-1)" "unprognostic (5.82e-2)" "unprognostic (1.44e-2)" "unprognostic (5.14e-3)" "unprognostic (5.38e-2)" 18.0 17.4 23.2 14.5 24.4 46.2 16.0 24.9 23.7 18.4 30.9 21.1 18.4 12.0 13.6 45.7 13.7 13.0 25.6 23.2 31.1 21.8 19.2 17.5 26.2 22.2 23.1 9.8 13.3 8.0 29.2 20.7 24.2 13.9 21.8 33.6 20.7 9.2 42.4 40.5 18.6 11.0 21.0 31.2 30.4 92.2 31.5 21.9 15.2 30.7 29.2 21.4 20.8 23.6 46.5 30.1 27.1 14.9 9.5 23.6 29.7 17.5 13.2 27.3 36.5 37.5 38.7 77.4 36.6 11.9 41.6 31.3 52.4 112.7 24.8 22.9 28.3 97.8 36.0 40.7 21.0 57.4 60.1 10.7 31.9 70.7 37.9 33.7 80.0 32.3 30.4 27.8 44.7 49.3 36.4 48.5 34.6 32.2 18.0 28.5 19.2 26.5 58.4 58.9 37.3 25.8 27.9 31.6 23.4 41.8 31.5 46.1 51.5 30.9 13.5 24.0 32.3 24.1 28.4 137.8 25.2 52.7 19.2 21.3 14.8 35.6 12.3 20.6 12.2 24.9 17.0 16.3 22.2 17.8 17.2 14.2 23.0 12.4 18.3 33.5 21.7 11.8 23.2 24.4 24.9 23.7 23.2 31.1 22.2 23.1 24.2 21.0 31.5 23.6 40.2 6.4 10.1 5.9 19.5 24.0 22.1 72.3 18.8 4.4 16.3 15.2 17.8 18.6 31.6 12.9 4.2 59.8 14.0 81.4 31.3 43.9 184.7 16.7 6.6 30.5 15.0 29.0 15.6 40.0 105.1 14.1 41.8 14.4 20.3 9.0 22.1 16.6 52.2 5.0 11.3 20.4 36.7 17.9 15.0 49.6 6.2 16.4 23.2 6.5 14.1 22.8 14.4 9.0 10.9 165.1 76.0 7.2 26.4 20.7 48.8 80.9 31.5 14.1 0.0 18.5 15.6 209.0 40.3 35.3 39.9 73.2 16.4 11.9 35.9 34.7 INPP4A INPP4 ENSG00000040933 "Inositol polyphosphate-4-phosphatase type I A" Q96PE3 2 98444854-98594392 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 150.5;Inhibitory neurons: 124.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001628 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Nuclear membrane" "HPA001628: AB_10961254" "unprognostic (3.45e-1)" "unprognostic (2.39e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.70e-6)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "unprognostic (1.15e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (9.65e-2)" "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (4.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" 8.7 8.2 15.9 13.2 19.5 12.7 6.1 18.8 22.0 7.0 1.0 11.3 7.3 7.5 5.2 7.7 6.6 9.9 10.5 15.9 9.9 5.2 4.1 9.6 17.2 9.2 3.5 7.0 6.6 8.9 7.7 8.1 9.2 6.0 7.9 10.7 5.6 6.3 8.4 4.1 8.8 9.8 4.7 16.7 7.3 5.9 5.9 20.3 5.9 11.6 12.5 10.8 5.5 10.1 12.7 11.0 18.2 14.8 10.4 11.1 19.2 10.0 9.4 10.9 11.3 14.6 11.5 7.8 13.3 15.4 14.0 12.6 12.6 11.1 8.5 27.7 10.9 9.5 9.7 6.5 8.8 17.3 34.3 9.9 9.9 10.6 9.0 9.5 15.1 44.9 8.5 67.4 8.3 16.2 26.3 16.8 17.6 7.4 11.3 12.0 12.5 51.9 5.6 41.6 12.8 15.7 12.1 10.1 9.5 18.7 4.8 13.8 14.3 12.7 17.9 10.1 7.5 50.2 31.1 5.8 10.5 16.2 11.5 1.1 1.0 2.3 2.8 2.2 3.3 0.4 1.6 1.8 1.1 0.1 2.2 2.5 1.1 3.2 3.4 3.3 0.9 1.0 15.9 19.5 18.8 22.0 15.9 9.9 9.2 3.5 9.2 4.7 5.9 10.1 14.6 6.4 13.1 50.9 11.2 8.0 6.4 2.8 9.1 49.7 5.3 4.2 12.6 2.8 7.8 5.5 8.4 10.2 64.6 4.1 3.9 4.0 13.5 6.2 9.1 14.2 5.4 7.2 150.5 1.5 8.7 9.9 6.6 6.3 0.0 22.4 14.3 3.4 10.5 33.7 124.4 5.6 4.1 36.4 18.4 10.9 9.3 25.3 10.6 73.1 26.8 8.4 71.1 55.8 26.1 3.8 2.5 12.0 48.6 5.9 1.2 3.3 5.1 14.1 6.6 9.9 12.4 8.6 14.0 5.2 6.1 9.4 48.3 9.4 3.6 6.8 INSC ENSG00000188487 "INSC spindle orientation adaptor protein" Q1MX18 11 15112424-15247208 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 25.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.9;Early spermatids: 4.6;Exocrine glandular cells: 3.1;Oligodendrocyte precursor cells: 8.0;Pancreatic endocrine cells: 10.9;Proximal tubular cells: 8.9" "Cancer enhanced" "Detected in some" "melanoma: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 11.7;hTERT-HME1: 6.0;Karpas-707: 3.3;LHCN-M2: 3.6;TIME: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA039769 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039769: AB_10697556" "unprognostic (1.64e-2)" "unprognostic (6.54e-2)" "unprognostic (1.45e-3)" "unprognostic (1.59e-1)" "unprognostic (6.00e-2)" "unprognostic (4.59e-3)" "unprognostic (6.88e-2)" "unprognostic (3.44e-3)" "unprognostic (3.69e-1)" "unprognostic (3.59e-2)" "unprognostic (2.63e-1)" "unprognostic (2.31e-1)" "unprognostic (3.30e-3)" "unprognostic (2.31e-1)" "unprognostic (1.35e-1)" "unprognostic (2.50e-2)" "unprognostic (5.00e-2)" 0.2 0.8 0.2 1.0 0.1 0.6 0.2 0.1 0.2 1.1 0.1 4.7 2.1 0.1 0.1 0.5 0.3 0.6 1.2 0.1 0.2 0.3 0.2 0.9 0.0 0.3 0.2 0.1 0.9 25.3 0.2 0.0 0.2 1.0 1.8 0.0 0.5 1.0 0.0 0.1 3.0 0.5 0.2 0.1 2.4 0.7 0.1 0.2 0.3 0.1 0.0 0.8 0.8 0.2 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.4 0.0 0.0 0.0 0.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.5 0.6 6.0 0.0 0.0 0.0 0.0 3.3 3.6 0.0 0.0 0.2 0.0 0.1 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 1.0 0.0 0.0 1.5 0.2 0.0 0.5 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.9 0.1 4.6 0.2 0.0 0.1 1.8 0.0 0.5 3.1 0.0 0.9 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.0 0.0 10.9 0.0 0.0 0.1 0.2 0.0 8.9 0.0 0.0 0.0 0.0 1.1 1.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 2.6 IRX5 IRX-2a ENSG00000176842 "Iroquois homeobox 5" P78411 16 54930865-54934485 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Vision" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 14.0;skin 1: 16.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 40.3;Breast myoepithelial cells: 55.5;Granulosa cells: 43.8;Muller glia cells: 43.1;Squamous epithelial cells: 33.9" "Cancer enhanced" "Detected in many" "breast cancer: 20.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.1;T-47d: 36.6;THP-1: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047130 Approved "Nuclear speckles,Microtubules,Cytosol" No NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "Microtubules, Cytosol" "HPA047130: AB_10962983" "unprognostic (2.63e-1)" "unprognostic (4.49e-2)" "unprognostic (8.03e-2)" "unprognostic (8.56e-2)" "unprognostic (1.42e-2)" "unprognostic (3.89e-2)" "unprognostic (5.38e-3)" "prognostic favorable (4.59e-4)" "unprognostic (8.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (1.17e-3)" "unprognostic (3.34e-2)" "unprognostic (8.90e-2)" "unprognostic (1.77e-3)" "unprognostic (4.28e-2)" 1.7 0.6 1.3 0.0 1.5 0.0 14.0 4.1 0.4 1.8 0.3 0.2 0.0 0.1 0.0 7.2 0.2 0.1 9.8 0.3 1.9 6.9 0.0 6.4 0.0 3.6 4.1 0.3 0.1 0.3 0.4 0.0 3.1 3.4 0.0 1.3 10.2 0.2 1.4 16.9 0.0 0.0 3.6 0.0 2.6 0.7 4.6 0.3 0.1 1.1 0.0 0.6 5.9 3.5 0.8 0.5 8.6 3.2 3.1 0.6 0.4 3.3 8.2 1.1 0.8 1.9 0.8 0.0 0.7 4.5 0.3 8.4 3.0 3.6 0.6 6.0 4.1 0.9 3.4 0.0 0.1 2.0 3.3 0.8 15.1 5.4 2.3 1.5 0.0 4.8 0.5 0.0 6.2 3.3 9.6 12.3 0.1 1.3 2.4 5.0 4.4 0.5 27.1 0.2 2.9 3.0 1.4 7.3 3.9 0.0 36.6 20.2 0.5 5.9 0.2 4.2 1.3 3.6 2.3 2.9 9.6 3.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 4.1 0.4 0.3 1.9 3.6 4.1 3.1 3.6 4.6 3.5 2.4 9.6 21.9 0.0 0.1 8.3 9.7 6.7 15.9 8.6 40.3 55.5 11.1 0.0 15.4 0.0 0.0 0.2 1.0 0.2 0.0 0.3 1.0 9.6 1.2 1.6 0.0 0.0 0.0 0.6 0.0 5.3 7.7 12.2 0.0 43.8 0.0 0.0 0.2 1.7 0.0 0.8 4.1 0.0 2.7 2.4 0.0 0.6 5.4 0.0 0.0 43.1 0.0 0.0 0.0 2.9 0.3 0.0 0.3 4.8 0.0 1.5 13.0 1.9 0.0 8.3 5.2 0.7 2.8 33.9 8.0 0.0 0.4 0.0 0.5 8.5 IRX6 "IRX-3, IRX7" ENSG00000159387 "Iroquois homeobox 6" P78412 16 55324203-55330756 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.8;heart muscle: 9.8;skin 1: 8.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.5;Collecting duct cells: 5.5;Hofbauer cells: 4.7;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HEK 293: 1.9;RPTEC TERT1: 7.1;SK-MEL-30: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018332 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" "HPA018332: AB_1851920" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (4.93e-4)" "unprognostic (2.48e-2)" "unprognostic (6.50e-2)" "unprognostic (3.46e-1)" "prognostic favorable (3.34e-4)" "unprognostic (3.63e-2)" "unprognostic (4.36e-2)" "unprognostic (2.93e-2)" "unprognostic (1.50e-2)" "unprognostic (2.83e-2)" "unprognostic (9.63e-3)" "unprognostic (7.12e-3)" "unprognostic (5.48e-2)" "unprognostic (5.23e-3)" 9.8 0.1 0.2 0.0 0.6 0.0 4.8 1.1 0.3 2.3 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.1 9.8 0.0 1.1 2.7 0.0 1.8 0.1 0.5 0.8 0.2 0.1 1.7 0.2 0.1 0.6 0.2 0.0 1.6 1.9 0.0 2.8 8.9 0.3 0.1 0.2 1.3 0.0 0.4 0.6 2.2 0.6 1.3 1.1 0.0 0.5 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.1 0.0 1.1 4.8 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 1.1 0.3 0.0 1.1 0.5 0.8 0.6 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.1 0.8 0.0 0.5 0.0 7.5 0.4 0.6 1.3 0.0 1.2 5.5 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.8 0.0 0.6 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.7 5.1 0.0 0.1 3.6 0.0 0.6 1.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.3 0.1 0.5 0.0 1.0 0.1 0.0 0.0 0.0 0.0 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.6" "Cell type enhanced" "Detected in many" "Adipocytes: 264.1;Endothelial cells: 120.5;Hepatocytes: 110.5;Sertoli cells: 98.6;Smooth muscle cells: 143.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.5;HHSteC: 4.5;SH-SY5Y: 1.7;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain NA NA 6300000 "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" 13.9 22.4 0.6 1.0 0.8 0.0 10.2 0.7 0.9 5.1 0.4 36.6 1.1 16.3 2.5 5.7 9.9 2.2 10.6 0.5 0.8 11.0 17.1 22.1 0.8 0.8 0.8 3.6 3.1 2.1 2.3 5.8 0.8 12.6 2.7 0.1 2.3 7.2 4.6 2.3 12.5 5.8 0.8 27.9 16.6 0.8 0.8 0.2 9.7 2.5 0.4 17.9 5.1 0.9 0.0 0.0 0.3 0.0 1.4 0.4 0.1 0.3 1.3 0.3 0.7 0.7 0.0 0.0 0.1 4.5 0.5 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.3 0.3 4.5 0.0 0.0 0.7 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 1.7 0.5 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.7 0.9 0.5 0.8 0.8 0.8 0.8 0.8 0.8 0.9 264.1 54.5 26.8 2.9 1.7 3.2 4.7 1.5 2.8 1.8 3.6 13.8 12.6 5.7 8.7 5.5 2.1 1.5 2.9 5.5 1.9 3.0 21.3 7.7 41.8 120.5 16.4 5.3 3.6 5.4 16.8 40.2 6.1 22.1 10.1 1.0 77.1 110.5 2.2 0.0 19.5 14.0 0.0 7.2 8.2 6.1 9.3 5.6 7.2 63.7 9.1 0.4 0.0 1.5 4.2 19.6 7.7 8.2 2.9 3.2 6.5 15.1 6.3 2.0 98.6 18.6 143.9 0.9 1.1 0.5 3.1 3.4 46.0 13.6 14.0 2.3 ITGA8 ENSG00000077943 "Integrin subunit alpha 8" P53708 10 15513954-15719922 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 37.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.8;Inhibitory neurons: 56.1;Microglial cells: 34.7;Oligodendrocyte precursor cells: 64.8;Plasma cells: 25.5;Sertoli cells: 52.6;Smooth muscle cells: 57.6" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;HMC-1: 19.8;HSkMC: 8.7;U-266/84: 9.7" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 14.1" HPA003432 Approved Approved "Plasma membrane" NA NA 200000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003432: AB_1851825" "unprognostic (2.15e-1)" "unprognostic (1.22e-3)" "unprognostic (1.05e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (8.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "unprognostic (6.82e-2)" "unprognostic (3.80e-1)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (4.10e-3)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (2.26e-1)" "unprognostic (6.03e-2)" 8.6 10.5 1.6 2.1 2.1 0.1 2.7 1.9 5.0 23.8 8.0 6.1 6.7 9.7 5.5 9.8 8.8 6.7 7.7 7.0 0.9 10.0 0.7 20.8 3.2 1.5 2.8 5.7 0.8 4.7 3.2 0.2 1.1 37.4 6.1 1.6 1.8 30.8 2.9 3.3 6.8 9.1 1.5 19.9 19.3 0.6 1.5 1.0 5.6 6.9 4.4 15.7 9.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 8.4 2.5 0.0 0.0 0.0 0.0 19.8 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.7 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.1 1.9 5.0 7.0 0.9 1.5 2.8 1.1 1.5 1.5 2.2 1.2 0.0 1.3 0.7 2.4 1.0 1.9 0.0 0.6 6.3 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 4.0 11.4 0.0 0.0 82.8 0.0 0.0 10.1 0.0 0.2 0.0 0.0 4.2 0.0 0.1 0.0 56.1 0.0 0.0 0.0 1.8 0.1 0.9 0.5 1.8 34.7 0.0 13.6 0.0 64.8 4.0 0.0 0.0 0.0 25.5 1.5 0.0 0.0 0.0 0.3 52.6 11.3 57.6 0.0 0.2 0.4 1.1 0.0 1.2 0.1 0.1 1.4 JAM2 "C21orf43, CD322, JAM-B, JAMB, VE-JAM" ENSG00000154721 "Junctional adhesion molecule 2" P57087 21 25639258-25717562 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 63.5" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Astrocytes: 81.6;Endothelial cells: 148.7;Hepatic stellate cells: 112.8;Microglial cells: 82.4;Oligodendrocyte precursor cells: 76.9" "Cancer enriched" "Detected in all" 9 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.5;BJ hTERT+: 16.5;HDLM-2: 16.7;hTERT-RPE1: 22.5;U-138 MG: 18.1;U-87 MG: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028789, HPA077346" Supported "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA028789: AB_2732443, HPA077346: AB_2732341" "unprognostic (1.42e-1)" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.51e-4)" "unprognostic (2.61e-2)" "unprognostic (4.55e-1)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.81e-1)" "unprognostic (8.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.18e-1)" "unprognostic (2.20e-1)" "unprognostic (4.85e-3)" 20.5 15.8 16.6 3.7 21.5 0.3 16.8 24.0 21.8 16.8 12.8 17.8 6.1 18.5 11.2 7.1 16.1 12.9 19.2 19.2 22.0 9.2 2.2 15.5 3.6 25.9 23.1 16.1 2.8 4.3 8.1 63.5 21.3 9.4 7.9 7.1 6.1 15.4 7.8 5.5 10.7 19.6 26.8 1.6 10.2 17.6 25.2 2.6 10.3 13.2 5.0 11.6 13.2 23.0 0.0 0.0 25.5 0.1 1.0 0.2 0.5 0.8 16.5 2.0 7.6 0.0 0.0 0.1 0.0 0.2 9.7 0.1 2.2 0.0 4.6 16.7 0.7 0.1 0.1 0.1 0.0 0.1 0.1 1.4 0.0 1.8 0.1 22.5 0.0 0.6 0.0 0.2 8.0 0.0 0.4 0.1 8.1 0.2 0.0 3.2 5.3 0.1 0.0 0.0 0.4 3.7 0.2 0.3 0.0 0.3 0.9 0.2 0.0 18.1 1.7 0.1 2.5 1.8 0.1 0.0 13.4 0.1 0.7 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.4 0.6 0.1 0.4 0.0 0.1 16.6 21.5 24.0 21.8 19.2 22.0 25.9 23.1 21.3 26.8 25.2 23.0 173.8 0.0 2.3 81.6 0.9 7.5 1.4 0.0 2.2 1.4 1.4 9.1 33.2 0.0 0.0 3.7 14.6 0.3 0.5 0.0 0.0 0.2 16.5 1.0 4.7 148.7 0.0 0.0 15.2 0.2 5.3 28.5 0.5 2.1 0.0 4.5 112.8 0.5 1.3 0.0 45.0 0.0 0.0 1.8 10.7 15.6 9.9 2.8 16.0 82.4 0.0 1.8 0.0 76.9 4.1 0.1 0.0 24.5 1.2 1.5 0.0 0.0 0.7 5.2 0.0 5.7 7.0 6.7 4.4 0.8 6.7 0.8 1.6 2.1 0.0 1.2 JARID2 JMJ ENSG00000008083 "Jumonji and AT-rich interaction domain containing 2" Q92833 6 15246069-15522042 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.8" "Cell type enhanced" "Detected in all" "Langerhans cells: 195.0" "Cancer enhanced" "Detected in all" "testis cancer: 34.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 73.8;SuSa: 78.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063889, CAB069890" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Mitochondria" "CAB069890: AB_10000529, HPA063889: AB_2685143" "unprognostic (5.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (4.87e-3)" "unprognostic (6.35e-2)" "unprognostic (2.57e-2)" "unprognostic (1.30e-2)" "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (3.26e-3)" "unprognostic (7.04e-2)" "unprognostic (4.48e-2)" "unprognostic (2.78e-2)" "unprognostic (1.99e-1)" 7.3 4.7 6.7 9.2 7.1 57.8 6.0 23.6 8.7 5.3 3.7 5.0 5.7 5.0 6.7 13.7 3.9 4.4 6.4 7.5 6.2 4.1 3.6 7.2 9.0 7.1 6.8 5.7 3.5 3.6 4.4 7.1 7.8 4.5 4.6 20.0 6.4 3.3 11.8 13.4 6.8 4.1 5.2 10.6 7.0 16.0 8.0 20.0 3.8 4.3 9.8 5.8 6.8 8.2 12.4 8.5 34.0 19.6 4.1 4.0 33.5 3.5 8.3 4.5 5.5 8.8 9.4 6.5 12.3 7.1 6.8 6.3 8.0 20.1 4.1 13.0 12.4 23.3 10.6 11.6 4.6 23.9 26.3 5.7 12.3 6.6 26.2 13.4 4.7 73.8 30.5 10.8 2.7 12.6 47.6 44.6 36.4 6.1 3.8 20.9 10.4 18.6 4.2 13.0 26.2 15.0 7.3 24.9 32.1 78.1 8.7 25.0 8.5 20.6 11.4 11.5 12.3 6.9 17.8 11.7 7.0 21.9 26.6 10.1 3.8 3.2 3.4 2.4 2.9 2.5 1.6 2.1 3.1 3.4 2.1 2.9 13.2 4.9 2.7 4.4 1.4 2.1 6.7 7.1 23.6 8.7 7.5 6.2 7.1 6.8 7.8 5.2 8.0 8.2 30.1 6.4 12.8 175.3 40.7 80.4 10.7 23.0 31.9 74.2 28.3 23.1 10.5 15.7 17.1 5.5 87.6 27.0 62.9 10.0 1.9 8.2 89.2 30.7 18.0 27.1 26.8 50.9 125.9 4.4 25.0 17.6 19.9 77.5 25.3 14.8 15.7 13.8 24.0 154.8 124.4 16.4 16.2 61.3 195.0 40.8 8.7 89.5 26.6 97.4 49.1 134.0 54.6 136.7 136.6 15.6 9.3 8.6 34.9 6.8 16.6 3.8 8.7 89.7 6.6 18.1 23.6 9.4 71.1 43.4 151.6 25.2 43.2 17.4 14.7 15.4 JPT1 "ARM2, HN1, HN1A" ENSG00000189159 "Jupiter microtubule associated homolog 1" Q9UK76 17 75135248-75168281 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 406.9" "Cell type enhanced" "Detected in many" "Ductal cells: 371.3;Exocrine glandular cells: 437.2;Extravillous trophoblasts: 1344.2;monocytes: 375.7;Pancreatic endocrine cells: 1434.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 767.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059729 Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA 40000 "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA059729: AB_2684114" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-3)" "unprognostic (3.57e-3)" "unprognostic (6.71e-2)" "unprognostic (2.51e-3)" "prognostic unfavorable (1.58e-7)" "unprognostic (3.58e-2)" "unprognostic (1.37e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.25e-3)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.77e-7)" "unprognostic (1.83e-1)" "unprognostic (8.99e-2)" "unprognostic (4.84e-2)" "unprognostic (1.51e-1)" 26.1 74.9 44.0 87.5 43.7 83.5 21.3 49.4 54.7 44.1 31.0 140.1 119.2 18.0 7.3 225.1 15.5 63.7 23.3 44.3 54.4 72.2 49.1 49.3 87.6 38.6 42.8 13.4 22.6 6.7 24.3 66.3 49.3 28.3 70.4 17.0 62.1 27.8 96.1 40.7 141.6 23.4 34.3 100.5 134.2 406.9 53.1 88.0 16.1 24.3 91.5 93.9 75.7 36.3 775.3 743.0 371.8 384.7 75.5 75.2 309.5 391.8 111.5 364.6 278.0 614.8 449.1 210.1 247.4 303.0 401.7 446.5 344.3 481.9 278.5 215.7 438.3 336.1 275.2 624.8 177.5 256.3 318.3 117.1 218.4 307.3 308.7 107.1 672.2 388.7 197.3 431.3 335.4 561.4 845.0 248.7 216.9 627.8 979.0 520.8 447.5 326.8 392.7 479.1 465.4 373.8 553.8 293.3 213.4 393.8 786.0 154.9 395.1 214.3 615.7 305.0 469.0 165.9 298.1 332.5 186.9 233.4 254.4 241.7 127.0 372.6 79.6 187.8 57.2 102.3 109.3 96.8 100.7 57.2 51.6 76.1 767.6 74.5 206.7 67.4 202.6 118.4 44.0 43.7 49.4 54.7 44.3 54.4 38.6 42.8 49.3 34.3 53.1 36.3 61.6 25.6 18.1 0.0 36.2 0.0 0.0 0.0 0.0 0.0 81.8 133.2 0.0 0.0 18.0 246.5 0.0 137.6 171.2 0.0 99.7 371.3 0.0 113.2 79.7 32.9 0.0 0.0 0.0 437.2 1344.2 40.4 0.0 194.0 7.6 179.6 0.0 0.0 319.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.5 0.0 0.0 375.7 0.0 0.0 0.0 0.0 1434.1 0.0 0.0 13.9 0.0 0.0 203.3 16.8 0.0 0.0 0.0 76.2 0.0 0.0 0.0 0.0 96.9 73.9 95.0 0.0 0.0 KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Growth regulation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016953, HPA074328" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Vesicles, Cytosol" "HPA016953: AB_1851277, HPA074328: " "unprognostic (2.20e-1)" "unprognostic (3.58e-1)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (7.16e-2)" "unprognostic (1.29e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-1)" "unprognostic (2.74e-1)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "prognostic favorable (1.10e-13)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.54e-2)" 31.6 30.0 38.7 23.8 41.0 52.9 32.1 41.7 48.8 39.5 38.6 43.6 21.6 45.1 33.7 34.9 44.9 20.5 32.4 37.9 38.9 32.9 26.3 29.5 28.0 40.0 39.5 39.2 32.7 45.6 33.7 29.9 41.2 33.1 27.0 31.0 29.6 36.3 42.8 47.6 32.2 35.2 40.0 34.3 35.9 45.2 39.9 39.3 38.2 34.6 30.2 39.5 34.8 43.8 37.2 44.1 40.1 29.6 31.3 32.7 41.1 26.7 43.6 44.0 38.0 32.6 42.2 34.3 36.2 47.4 47.5 30.8 50.8 45.1 26.4 44.4 32.5 50.6 36.3 38.9 44.6 55.7 56.4 35.2 49.7 28.9 59.0 33.7 28.1 39.1 52.5 51.1 42.0 68.2 45.7 62.3 33.9 26.8 28.4 38.2 26.5 63.3 40.6 56.2 37.1 38.9 25.4 46.5 51.2 20.8 45.9 34.2 36.3 33.9 30.4 27.6 28.0 38.7 43.7 50.4 29.7 27.0 29.3 42.7 33.6 58.8 33.4 32.0 29.6 28.2 28.8 34.2 34.1 30.4 36.5 29.8 34.8 35.8 34.6 20.9 31.0 36.4 38.7 41.0 41.7 48.8 37.9 38.9 40.0 39.5 41.2 40.0 39.9 43.8 17.6 12.8 17.5 10.7 26.0 21.2 44.2 60.2 17.6 44.9 17.3 15.0 1.0 25.8 33.8 29.5 31.3 51.3 25.6 27.1 35.2 42.2 11.1 20.2 14.2 18.7 30.4 12.4 7.5 51.5 42.6 21.1 20.4 19.8 33.7 27.0 18.2 10.9 36.3 38.7 8.7 25.1 42.7 17.6 15.2 11.1 28.0 20.4 42.7 3.7 38.8 40.3 33.0 7.1 13.8 39.4 30.6 38.7 10.4 24.2 23.3 32.6 30.0 44.8 46.0 27.6 27.0 61.1 27.8 14.6 21.3 102.5 21.6 29.2 26.2 31.0 KAT7 "HBO1, HBOA, MYST2, ZC2HC7" ENSG00000136504 "Lysine acetyltransferase 7" O95251 17 49788648-49835026 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, DNA replication, Transcription, Transcription regulation" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044470, HPA071116" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA044470: AB_10965785, HPA071116: " "unprognostic (1.30e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-3)" "unprognostic (2.20e-2)" "unprognostic (7.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (1.36e-1)" "unprognostic (6.26e-2)" "unprognostic (1.44e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-3)" "unprognostic (2.75e-1)" "unprognostic (5.03e-2)" "unprognostic (6.23e-2)" "unprognostic (7.68e-2)" 17.6 14.2 16.1 8.1 16.9 40.9 16.6 24.2 21.5 20.1 15.1 20.9 7.2 22.6 12.2 20.4 20.3 6.6 22.8 16.5 14.8 17.7 11.7 14.5 10.4 13.6 12.3 20.9 12.4 23.5 17.1 10.0 15.5 17.5 10.0 19.2 17.8 14.0 37.7 25.5 16.0 12.4 10.3 15.9 16.0 38.6 14.9 17.4 21.1 20.1 13.5 22.5 19.0 18.7 17.1 22.6 22.5 17.3 10.1 14.3 27.2 11.2 16.5 24.7 18.7 35.9 11.5 17.8 21.8 13.7 24.7 16.7 23.0 12.8 32.5 18.6 20.3 20.7 14.8 17.8 15.0 21.6 17.2 13.3 16.6 21.1 25.3 14.4 22.7 16.0 23.6 18.9 27.4 28.8 26.4 23.2 79.0 38.4 20.2 20.6 34.7 18.2 12.8 17.6 25.7 15.7 7.6 9.2 14.9 40.5 38.6 22.9 8.8 24.5 13.3 16.0 19.4 21.4 32.7 23.3 17.3 13.6 23.3 17.1 6.8 9.5 8.3 5.4 10.6 5.8 7.8 8.5 7.0 6.1 9.3 8.5 10.1 11.7 7.1 4.3 8.5 7.9 16.1 16.9 24.2 21.5 16.5 14.8 13.6 12.3 15.5 10.3 14.9 18.7 16.0 25.6 21.3 9.4 23.6 16.8 11.7 10.1 25.0 32.6 18.5 16.6 28.5 20.0 15.6 27.6 31.3 22.7 27.6 11.7 9.8 11.9 23.1 22.4 21.0 18.7 25.1 25.4 14.8 7.5 14.5 15.3 15.3 29.9 24.1 18.2 15.4 10.4 13.3 45.4 16.7 13.4 12.2 22.6 13.2 16.5 16.8 15.9 14.2 10.3 19.1 16.5 25.7 13.0 18.3 10.0 8.9 18.4 18.6 15.4 12.8 10.2 18.6 25.1 39.5 21.2 24.2 73.7 31.6 17.9 20.0 33.8 28.4 15.2 12.1 10.2 KCNH1 "eag, eag1, h-eag, hEAG, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134165 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 533.5;Inhibitory neurons: 261.0;Oligodendrocytes: 116.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 6.2;RH-30: 10.1;RPTEC TERT1: 6.0;SH-SY5Y: 12.9;SK-MEL-30: 12.9;T-47d: 9.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 34.0;cerebellum: 19.1;cerebral cortex: 23.9;hippocampal formation: 17.9;olfactory bulb: 8.9" "HPA014551, HPA019445, HPA076421" Enhanced Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA014551: AB_2669038, HPA019445: AB_1852118, HPA076421: " "unprognostic (9.12e-2)" "unprognostic (4.82e-3)" "unprognostic (2.63e-1)" "unprognostic (6.70e-2)" "unprognostic (3.56e-1)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (9.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.77e-2)" "unprognostic (1.42e-3)" "unprognostic (1.17e-1)" "unprognostic (8.89e-2)" "unprognostic (1.36e-1)" "unprognostic (9.70e-2)" 0.2 0.9 6.8 0.4 9.2 0.0 0.2 9.5 17.9 0.7 2.7 0.5 0.3 0.4 0.2 0.1 0.6 0.2 0.0 11.2 5.3 0.1 0.1 0.0 0.0 4.8 4.4 0.1 0.2 0.0 0.7 0.3 4.0 0.5 0.3 0.3 0.1 0.1 0.2 0.1 0.8 0.2 4.0 0.0 0.5 1.5 4.9 0.2 0.1 0.6 0.0 0.2 0.4 8.3 0.0 2.1 0.4 0.1 0.0 0.1 0.1 1.0 0.2 2.1 2.4 0.0 0.0 0.0 0.0 1.4 2.4 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 10.1 0.0 6.0 0.0 0.4 12.9 2.4 0.2 12.9 1.7 9.2 0.0 0.0 1.6 0.2 2.0 1.2 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 9.2 9.5 17.9 11.2 5.3 4.8 4.4 4.0 4.0 4.9 8.3 0.2 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 11.2 0.2 2.8 0.1 0.0 0.0 533.5 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 261.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 7.5 0.0 0.0 0.0 19.1 116.6 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNH8 "elk3, Kv12.1" ENSG00000183960 "Potassium voltage-gated channel subfamily H member 8" Q96L42 3 19148510-19535642 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.0;pituitary gland: 10.7" "Group enriched" "Detected in some" 63 "Oligodendrocyte precursor cells: 331.7;Oligodendrocytes: 989.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.4" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cell line enhanced" "Detected in some" "HAP1: 1.0;OE19: 1.9;SH-SY5Y: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA016586, HPA077537, HPA077773" Approved Supported "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA016586: AB_1852127, HPA077537: , HPA077773: " "unprognostic (6.68e-3)" "unprognostic (1.68e-1)" "unprognostic (2.99e-2)" "unprognostic (8.56e-6)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.88e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (1.69e-1)" "unprognostic (5.04e-3)" "unprognostic (2.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (3.89e-2)" "unprognostic (8.71e-5)" "unprognostic (1.72e-1)" 0.0 1.8 7.3 0.3 11.9 0.2 0.5 6.5 16.0 0.3 2.8 0.6 0.4 0.1 0.1 0.1 0.2 0.4 0.2 6.4 8.8 0.1 0.1 0.0 0.8 8.4 8.8 0.0 1.5 0.1 10.7 0.0 8.2 0.7 0.5 3.4 1.1 0.2 0.0 0.4 1.1 0.1 5.8 1.1 1.4 1.7 9.7 0.4 0.2 0.0 0.7 0.1 0.3 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 7.3 11.9 6.5 16.0 6.4 8.8 8.4 8.8 8.2 5.8 9.7 15.4 0.0 0.0 0.0 2.0 9.7 0.5 1.6 0.0 0.0 4.2 1.1 2.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 3.2 0.1 0.1 0.1 3.6 0.0 9.3 0.6 0.0 0.1 2.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 10.4 1.5 0.0 0.0 0.0 1.9 0.0 0.1 3.6 1.0 0.0 3.4 0.0 331.7 989.4 0.5 0.2 0.0 0.1 1.5 0.0 0.0 0.0 1.0 0.0 0.2 0.5 1.2 3.4 0.0 0.0 0.1 0.3 0.1 0.6 0.4 KCNIP1 KCHIP1 ENSG00000182132 "Potassium voltage-gated channel interacting protein 1" Q9NZI2 5 170353487-170736632 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7;choroid plexus: 15.1;epididymis: 21.6" "Cell type enhanced" "Detected in some" "Astrocytes: 57.8;Horizontal cells: 50.5;Inhibitory neurons: 221.4;Microglial cells: 167.7;Oligodendrocyte precursor cells: 196.1" "Cancer enriched" "Detected in some" 18 "glioma: 22.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "RPTEC TERT1: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022864, HPA066717" Uncertain Approved Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA022864: AB_1858712, HPA066717: " "unprognostic (7.75e-5)" "unprognostic (2.66e-2)" "unprognostic (6.78e-2)" "unprognostic (3.22e-4)" "unprognostic (4.51e-2)" "unprognostic (3.49e-1)" "unprognostic (1.25e-2)" "unprognostic (2.69e-1)" "unprognostic (5.46e-2)" "unprognostic (6.62e-3)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.55e-1)" "unprognostic (2.58e-2)" "unprognostic (1.63e-1)" "unprognostic (2.39e-1)" "unprognostic (6.05e-2)" 0.5 4.2 23.5 0.5 26.5 0.0 1.0 19.4 28.3 2.7 15.1 0.7 0.2 1.6 21.6 0.3 1.7 1.8 0.4 21.8 32.6 3.8 0.1 1.0 0.5 24.3 26.6 0.3 1.4 1.3 1.0 1.2 24.7 1.5 0.5 5.8 0.4 5.6 0.1 0.4 0.3 1.1 28.7 1.5 0.4 2.7 32.7 0.1 0.7 0.2 0.4 0.5 0.6 19.6 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 58.7 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 26.5 19.4 28.3 21.8 32.6 24.3 26.6 24.7 28.7 32.7 19.6 0.0 0.0 0.0 57.8 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 2.0 1.2 0.0 0.0 18.6 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 50.5 221.4 0.0 0.0 0.0 0.6 0.7 5.0 0.1 0.0 167.7 0.0 0.2 0.0 196.1 2.8 0.0 0.0 11.7 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 KCNIP2 KCHIP2 ENSG00000120049 "Potassium voltage-gated channel interacting protein 2" Q9NS61 10 101825974-101843920 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 227.4;brain: 139.6;heart muscle: 307.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 54.3;Cardiomyocytes: 135.7;Cone photoreceptor cells: 25.0;Excitatory neurons: 23.3;Horizontal cells: 48.8;Inhibitory neurons: 41.9" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 21.3;HMC-1: 12.7" "Group enriched" "Detected in all" 4 "amygdala: 96.8;basal ganglia: 234.9;cerebral cortex: 106.9;hippocampal formation: 142.6;olfactory bulb: 144.0" "Low region specificity" "Detected in all" HPA066717 Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA066717: " "unprognostic (5.92e-2)" "unprognostic (2.16e-1)" "unprognostic (3.48e-3)" "unprognostic (5.77e-4)" "unprognostic (1.34e-1)" "unprognostic (1.31e-3)" "unprognostic (8.80e-2)" "unprognostic (9.11e-3)" "unprognostic (1.14e-1)" "unprognostic (5.34e-2)" "unprognostic (3.18e-2)" "unprognostic (7.20e-2)" "unprognostic (1.49e-9)" "unprognostic (9.85e-2)" "unprognostic (1.81e-1)" "unprognostic (3.27e-1)" "unprognostic (8.37e-4)" 227.4 6.8 74.5 3.5 139.6 0.9 67.1 48.8 84.5 7.4 40.5 5.0 1.8 4.1 4.1 2.5 4.9 3.1 307.5 98.8 50.6 2.8 2.3 2.5 8.1 47.5 51.6 11.5 2.4 1.7 19.7 2.9 48.1 5.2 4.7 52.6 9.9 3.5 8.0 5.9 5.3 2.6 50.3 5.7 2.7 8.5 57.1 2.3 3.5 5.4 8.3 4.8 4.4 60.8 1.7 2.6 2.5 3.2 1.0 1.1 0.6 1.2 1.0 0.6 0.9 3.6 3.4 1.6 0.9 0.8 0.7 1.7 0.9 0.4 0.6 2.4 2.0 21.3 3.0 1.9 0.9 1.4 12.7 2.6 1.7 1.0 1.4 3.7 1.0 4.7 6.3 1.8 1.0 1.2 0.8 4.0 0.8 0.7 0.6 1.0 0.2 1.4 1.0 1.1 7.4 1.2 0.8 0.6 2.4 1.5 2.2 0.9 2.3 1.3 2.0 0.6 1.2 1.7 1.9 1.7 1.4 5.3 0.2 0.0 0.0 0.7 0.0 0.5 0.1 0.9 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 74.5 139.6 48.8 84.5 98.8 50.6 47.5 51.6 48.1 50.3 57.1 60.8 0.4 0.0 0.0 8.5 2.3 0.4 0.1 0.3 0.0 54.3 0.3 0.5 135.7 0.0 0.1 1.8 25.0 0.2 0.0 0.8 0.0 0.2 6.6 0.0 0.2 1.6 0.0 0.0 23.3 0.0 0.2 5.8 0.0 0.0 0.0 0.8 0.4 0.1 2.2 48.8 41.9 0.4 0.0 0.6 0.8 5.2 1.8 0.3 0.0 1.0 0.5 8.3 0.0 5.5 3.7 0.3 0.2 0.7 0.3 0.1 0.5 0.1 0.2 4.7 0.0 0.1 1.3 2.5 5.5 0.5 0.0 0.3 0.1 0.5 0.3 0.1 KCNJ5 "CIR, GIRK4, KATP1, Kir3.4, LQT13" ENSG00000120457 "Potassium inwardly rectifying channel subfamily J member 5" P48544 11 128891356-128921163 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 64.3;pancreas: 20.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 48.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "HBEC3-KT: 13.3" "Group enriched" "Detected in many" 6 "basal ganglia: 2.9;hypothalamus: 6.8;midbrain: 1.9;thalamus: 3.6" "Low region specificity" "Detected in all" "HPA014722, HPA017353, CAB022569" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "CAB022569: , HPA014722: AB_1852133, HPA017353: AB_1852135" "unprognostic (2.01e-1)" "unprognostic (2.43e-3)" "unprognostic (2.56e-3)" "unprognostic (5.81e-2)" "unprognostic (4.24e-2)" "unprognostic (3.60e-2)" "unprognostic (2.90e-1)" "unprognostic (3.54e-2)" "unprognostic (6.83e-2)" "unprognostic (1.96e-1)" "unprognostic (3.17e-1)" "unprognostic (9.29e-2)" "unprognostic (1.81e-2)" "unprognostic (6.82e-2)" "unprognostic (9.49e-2)" "unprognostic (1.88e-2)" "unprognostic (2.23e-2)" 1.5 64.3 1.2 0.6 0.9 0.4 0.9 0.6 2.0 1.3 0.2 0.8 0.8 0.3 0.9 1.0 0.9 2.2 8.5 0.7 3.2 5.4 0.4 5.9 1.6 3.7 1.7 0.9 20.4 1.3 11.9 7.3 2.7 1.3 0.7 1.0 0.9 9.6 0.4 0.4 0.5 0.6 1.7 13.6 2.3 1.1 7.9 5.8 0.5 0.4 0.5 1.5 0.4 3.9 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.3 13.3 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 1.2 0.9 0.6 2.0 0.7 3.2 3.7 1.7 2.7 1.7 7.9 3.9 0.2 0.0 10.0 0.3 0.2 1.5 2.2 4.7 0.0 2.7 0.2 1.4 7.6 0.0 0.3 1.8 0.0 0.8 0.1 0.0 0.0 0.1 2.3 0.2 0.2 0.6 0.0 0.0 0.2 3.9 0.7 1.1 0.0 0.3 0.0 0.2 0.4 0.1 48.3 1.7 3.1 0.0 0.0 2.2 2.9 7.8 0.9 10.9 3.6 3.7 1.2 0.3 3.1 0.5 0.1 0.8 0.0 0.7 0.3 0.6 0.0 0.1 0.3 1.4 0.0 0.9 0.2 0.9 0.5 0.5 1.7 1.2 0.6 2.3 0.0 0.6 KCNJ8 Kir6.1 ENSG00000121361 "Potassium inwardly rectifying channel subfamily J member 8" Q15842 12 21764955-21775600 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 71.3" "Group enriched" "Detected in many" 4 "Sertoli cells: 197.2;Smooth muscle cells: 61.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Cell line enhanced" "Detected in some" "BJ: 11.1;CACO-2: 58.4;SH-SY5Y: 30.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031066 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA031066: AB_10602240" "unprognostic (8.12e-3)" "unprognostic (1.89e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.81e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-2)" "unprognostic (3.90e-2)" "unprognostic (3.66e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (1.62e-6)" "unprognostic (4.70e-3)" "unprognostic (9.61e-2)" "unprognostic (1.73e-2)" "unprognostic (3.54e-3)" 28.6 17.3 4.9 3.2 5.4 0.0 22.1 4.8 5.7 17.0 11.6 15.6 1.2 18.8 0.7 3.6 14.8 1.8 71.3 4.7 5.0 13.9 41.9 13.8 2.5 5.2 5.3 16.8 42.4 1.8 7.8 3.0 5.1 13.0 0.3 0.8 6.4 8.4 17.1 5.8 5.9 5.5 5.2 8.0 12.7 1.0 7.2 0.6 16.1 4.5 0.4 15.1 11.5 4.7 0.0 0.1 0.9 0.0 1.4 3.2 0.0 11.1 4.4 6.5 1.9 58.4 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.1 0.0 4.3 2.9 0.0 0.0 0.0 0.0 0.0 4.5 0.0 3.2 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.0 5.0 0.0 0.0 0.0 6.6 2.7 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.4 4.8 5.7 4.7 5.0 5.2 5.3 5.1 5.2 7.2 4.7 18.7 3.2 29.5 2.9 0.0 1.3 0.4 0.0 0.6 0.0 9.2 3.0 28.3 0.0 0.6 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.7 10.8 12.8 1.2 0.0 3.6 1.3 0.0 9.8 0.0 0.9 0.0 1.0 2.9 23.0 0.3 0.0 0.2 0.0 0.0 0.8 1.5 0.1 0.3 0.3 1.8 0.0 0.0 13.2 0.0 0.5 0.4 1.2 0.0 0.7 0.1 0.4 0.0 0.0 0.0 2.0 197.2 3.3 61.6 0.0 1.0 0.1 0.9 0.3 0.3 0.5 0.2 0.6 KCNK1 "DPK, K2p1.1, TWIK-1" ENSG00000135750 "Potassium two pore domain channel subfamily K member 1" O00180 1 233614106-233672514 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 157.8;Horizontal cells: 200.2;Prostatic glandular cells: 222.9;Urothelial cells: 371.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 69 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 69 "dendritic cells: 6.9" "Cell line enhanced" "Detected in many" "HeLa: 64.7;SCLC-21H: 62.5;U-266/70: 137.3;U-266/84: 134.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 117.0" "HPA016049, CAB022588" Approved Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB022588: , HPA016049: AB_1855571" "unprognostic (7.06e-3)" "unprognostic (1.76e-1)" "unprognostic (4.64e-2)" "unprognostic (7.46e-2)" "unprognostic (9.15e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.84e-4)" "unprognostic (4.32e-2)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (7.29e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" 3.9 4.1 17.7 2.9 19.8 0.3 5.7 58.0 28.4 7.8 50.4 15.7 16.9 6.1 30.9 20.9 10.9 12.1 41.0 24.3 13.7 9.2 12.1 4.4 1.0 23.5 17.8 7.3 5.5 16.2 22.2 6.8 24.1 6.4 13.9 18.5 15.1 11.3 0.4 13.3 12.6 3.8 15.4 0.9 38.1 0.9 16.3 0.5 7.2 0.9 4.4 11.5 14.4 21.3 33.2 18.3 0.1 0.0 0.0 0.0 50.2 8.8 0.0 0.0 0.0 0.0 52.9 0.0 20.7 6.8 7.3 47.1 8.9 15.2 0.0 0.1 15.8 0.0 64.7 0.0 0.5 0.0 1.8 3.9 17.0 0.0 12.4 1.1 0.2 17.7 7.9 15.0 0.0 12.6 12.2 0.1 10.9 38.5 41.0 0.0 2.7 3.7 16.0 28.4 62.5 11.8 33.5 14.3 0.0 1.0 4.1 0.1 0.0 0.1 25.8 0.0 1.0 137.3 134.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 17.7 19.8 58.0 28.4 24.3 13.7 23.5 17.8 24.1 15.4 16.3 21.3 0.4 9.6 22.9 5.9 0.6 63.3 136.7 32.6 3.4 2.9 23.0 6.0 54.7 12.8 44.6 18.4 4.2 0.5 3.0 91.0 1.9 29.2 1.1 52.7 26.4 3.5 29.3 0.0 157.8 48.3 14.0 31.2 50.4 89.3 0.0 15.0 0.0 8.9 0.6 200.2 61.0 56.3 24.4 0.3 4.4 0.2 1.5 1.0 10.6 12.2 0.0 72.6 0.0 36.2 73.2 96.3 82.4 0.0 0.2 222.9 10.6 8.8 42.9 5.1 0.0 2.3 6.9 0.6 3.2 19.1 47.6 0.8 1.4 0.5 31.2 371.6 KCNK10 "K2p10.1, PPP1R97, TREK-2, TREK2" ENSG00000100433 "Potassium two pore domain channel subfamily K member 10" P57789 14 88180103-88326907 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;intestine: 5.1;stomach 1: 2.6" "Group enriched" "Detected in some" 4 "dendritic cells: 12.5;Excitatory neurons: 43.8;Inhibitory neurons: 17.0;Oligodendrocyte precursor cells: 37.7;Oligodendrocytes: 11.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 62 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in single" 100 "dendritic cells: 10.0" "Cell line enhanced" "Detected in some" "OE19: 1.5;REH: 1.7;SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030462 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA030462: AB_10601919" "unprognostic (9.52e-3)" "unprognostic (1.17e-1)" "unprognostic (1.94e-2)" "unprognostic (1.08e-1)" "unprognostic (8.20e-2)" "unprognostic (1.45e-1)" "unprognostic (1.18e-1)" "unprognostic (2.25e-1)" "unprognostic (4.58e-1)" "unprognostic (1.23e-2)" "unprognostic (2.70e-1)" "unprognostic (2.45e-1)" "unprognostic (6.97e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-1)" "unprognostic (4.26e-3)" 0.0 0.3 4.0 0.4 3.6 0.2 0.0 5.1 4.1 0.2 0.0 1.3 5.1 0.0 0.0 1.1 0.0 0.0 0.0 4.4 2.9 2.4 0.0 0.1 0.1 4.2 2.9 0.0 1.4 0.0 0.5 0.0 3.5 0.0 0.7 0.1 0.2 0.0 0.0 0.0 2.6 0.1 2.3 0.1 2.6 0.5 2.4 0.0 0.0 0.0 0.4 0.0 0.2 4.6 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.1 1.7 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.1 4.0 3.6 5.1 4.1 4.4 2.9 4.2 2.9 3.5 2.3 2.4 4.6 0.0 0.0 0.0 0.7 0.1 0.6 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 12.5 2.1 0.0 0.0 0.7 0.0 0.0 0.1 1.8 0.0 43.8 0.6 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.0 1.6 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 37.7 11.9 0.1 0.3 0.0 0.0 0.0 1.5 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 3.2 0.0 0.0 0.1 0.0 1.6 0.1 KCNS1 Kv9.1 ENSG00000124134 "Potassium voltage-gated channel modifier subfamily S member 1" Q96KK3 20 45091214-45101127 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 22.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.0;Cholangiocytes: 7.2;Collecting duct cells: 1.8;Excitatory neurons: 6.2" "Cancer enriched" "Detected in many" 5 "cervical cancer: 6.1" "Region enhanced" "Detected in many" "cerebral cortex: 22.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBF TERT88: 1.3;HHSteC: 2.1;hTEC/SVTERT24-B: 1.0;THP-1: 1.8;U-87 MG: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.46e-2)" "unprognostic (2.95e-3)" "unprognostic (2.03e-1)" "unprognostic (3.11e-4)" "unprognostic (8.91e-3)" "unprognostic (6.01e-3)" "unprognostic (7.47e-2)" "unprognostic (8.94e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (6.74e-2)" "unprognostic (4.65e-2)" "unprognostic (6.35e-2)" "unprognostic (5.62e-2)" "unprognostic (3.06e-2)" "unprognostic (1.15e-1)" "unprognostic (1.39e-1)" 0.0 0.4 0.9 0.1 2.9 0.1 0.2 0.0 22.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.1 4.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.5 2.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.1 0.4 0.4 0.1 0.1 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.8 0.0 0.9 0.2 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 2.9 0.0 22.8 4.1 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 2.0 0.3 0.0 0.4 0.1 0.1 0.0 0.0 0.3 0.1 1.1 7.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 6.2 0.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 220.2;Inhibitory neurons: 240.5;Oligodendrocyte precursor cells: 310.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 3.2;hTERT-RPE1: 9.0;SCLC-21H: 7.5;SH-SY5Y: 5.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA051218: AB_2681392" "unprognostic (5.06e-2)" "unprognostic (2.94e-2)" "unprognostic (8.01e-2)" "unprognostic (5.10e-6)" "unprognostic (1.22e-3)" "unprognostic (1.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "unprognostic (9.56e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.67e-5)" "unprognostic (3.30e-4)" "unprognostic (2.95e-2)" "unprognostic (4.75e-1)" "unprognostic (1.72e-3)" 1.0 0.6 0.9 0.1 2.0 0.0 0.4 0.0 2.0 0.4 0.3 0.5 0.2 0.3 0.4 1.0 0.5 1.4 1.8 2.5 3.3 0.3 2.8 1.8 0.1 0.0 0.2 3.8 0.1 0.0 0.9 0.2 0.0 1.0 0.5 0.1 0.5 0.6 0.1 0.3 0.4 0.5 0.6 0.2 0.5 1.1 1.0 0.1 1.1 0.8 0.1 0.8 0.4 0.5 0.0 0.1 1.8 0.0 0.2 0.2 0.0 0.0 1.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.9 0.0 3.2 0.0 0.0 1.2 0.0 0.4 0.1 9.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 2.4 0.0 0.1 0.0 0.1 0.0 0.0 0.5 7.5 5.6 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.0 0.0 2.0 2.5 3.3 0.0 0.2 0.0 0.6 1.0 0.5 0.8 41.7 1.1 6.8 0.0 0.4 0.2 0.0 0.6 0.0 0.0 0.1 1.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.2 0.8 0.0 0.0 220.2 0.0 0.0 9.3 0.0 0.0 0.0 6.1 2.5 6.2 0.0 0.0 240.5 0.0 0.0 0.0 0.7 3.3 6.5 0.0 1.8 58.1 0.0 0.0 0.0 310.7 6.1 0.0 0.0 4.9 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.4 4.0 0.6 0.2 0.0 0.0 0.0 0.0 3.9 0.0 0.2 KCTD15 MGC25497 ENSG00000153885 "Potassium channel tetramerization domain containing 15" Q96SI1 19 33795933-33815763 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 44.4;Granulosa cells: 94.8;Hepatic stellate cells: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.8;eosinophil: 5.9;intermediate monocyte: 3.3;myeloid DC: 2.5;non-classical monocyte: 4.8" "Group enriched" "Detected in many" 6 "dendritic cells: 2.5;granulocytes: 5.9;monocytes: 4.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050822 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA050822: AB_2681250" "unprognostic (1.26e-2)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (6.62e-3)" "unprognostic (1.67e-2)" "unprognostic (2.66e-2)" "unprognostic (3.09e-2)" "unprognostic (5.60e-2)" "unprognostic (6.33e-2)" "unprognostic (5.58e-2)" "unprognostic (2.76e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.65e-8)" "unprognostic (1.40e-1)" "unprognostic (1.89e-3)" "unprognostic (6.13e-2)" "unprognostic (7.30e-2)" 19.2 6.3 29.4 11.3 28.0 6.1 14.2 24.9 34.9 38.8 15.0 41.3 7.0 43.1 3.2 34.8 36.1 10.8 19.1 28.7 29.6 24.7 12.9 24.7 3.0 26.0 30.2 22.7 32.5 4.5 10.3 11.0 24.2 25.0 6.0 15.2 11.6 19.0 6.0 73.2 15.7 20.7 25.8 17.4 23.3 10.5 30.2 1.3 23.0 6.4 4.1 32.0 31.3 23.3 16.7 37.5 33.2 50.8 10.8 5.7 26.2 21.6 4.0 11.7 6.1 21.2 11.1 0.1 47.6 30.3 5.5 19.3 24.3 16.9 4.4 18.1 42.7 68.5 25.3 20.7 29.8 13.3 12.0 11.2 69.4 4.5 26.5 0.0 23.2 9.8 17.3 0.4 2.0 42.0 0.5 37.8 30.4 27.9 62.8 32.0 17.9 6.3 13.3 7.5 25.7 88.0 42.0 59.0 80.0 14.1 43.7 34.7 38.3 54.7 48.9 1.1 3.8 40.9 2.3 27.2 0.1 23.0 68.4 0.6 1.8 5.9 0.0 3.3 0.1 0.0 0.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.5 0.7 29.4 28.0 24.9 34.9 28.7 29.6 26.0 30.2 24.2 25.8 30.2 23.3 17.8 0.0 1.7 44.4 0.3 15.8 3.3 4.1 10.8 3.5 5.4 5.0 3.2 1.5 2.9 0.0 10.4 0.2 0.4 0.9 3.9 0.7 0.7 3.4 15.1 15.3 1.2 4.2 1.9 8.4 0.4 5.5 1.5 2.5 8.8 94.8 27.8 2.0 1.2 1.7 5.3 3.6 0.0 3.7 5.4 1.9 4.4 3.7 5.4 4.7 3.1 5.0 0.0 11.1 0.3 2.1 1.0 9.1 0.1 3.9 0.3 0.2 0.7 11.7 0.0 3.1 8.7 0.0 1.9 14.3 19.5 0.3 0.7 2.4 1.9 3.1 KDM2A "CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA" ENSG00000173120 "Lysine demethylase 2A" Q9Y2K7 11 67119263-67258082 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012272, HPA044251" Supported Supported Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB012272: , HPA044251: " "unprognostic (7.43e-2)" "unprognostic (1.84e-1)" "unprognostic (4.09e-1)" "unprognostic (8.66e-2)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (6.05e-2)" "unprognostic (2.84e-1)" "unprognostic (4.46e-1)" "unprognostic (2.04e-3)" "unprognostic (3.27e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-2)" "unprognostic (3.30e-1)" "unprognostic (1.05e-1)" "unprognostic (5.61e-2)" "unprognostic (9.45e-3)" 19.5 13.2 10.7 27.2 10.6 47.1 19.7 18.0 12.1 24.3 14.1 23.3 14.7 29.1 17.4 31.9 19.3 19.0 17.4 10.6 11.2 14.3 19.9 24.0 27.5 12.6 10.7 24.5 13.0 16.1 13.1 18.0 10.9 21.6 17.1 18.5 21.3 19.2 33.8 29.4 23.9 24.0 9.7 27.0 18.9 29.0 11.9 27.8 19.0 24.5 28.7 23.9 25.9 10.9 49.9 31.8 17.6 27.7 17.1 27.0 13.5 21.5 26.6 41.0 27.9 48.7 25.4 38.8 37.5 33.3 23.8 48.2 31.3 22.5 33.1 66.4 13.4 28.9 39.2 11.7 16.9 24.5 38.1 21.7 23.9 39.4 25.7 20.7 29.9 22.7 27.4 54.4 18.6 35.4 32.5 18.1 36.1 29.8 25.6 39.9 29.4 21.4 14.7 33.7 24.2 18.9 71.0 38.6 39.0 21.6 59.9 23.9 38.7 25.0 16.7 34.5 18.8 29.3 35.4 25.4 22.0 17.2 17.8 0.4 1.1 0.3 2.5 0.8 2.7 3.6 1.9 2.3 0.6 3.6 1.9 1.9 2.7 2.7 0.5 0.9 2.6 1.9 10.7 10.6 18.0 12.1 10.6 11.2 12.6 10.7 10.9 9.7 11.9 10.9 41.4 38.5 35.8 75.1 56.6 41.2 23.3 23.4 75.7 75.3 40.3 30.9 31.1 34.3 31.0 16.5 137.6 23.9 77.5 43.2 0.0 17.3 20.6 84.8 63.0 38.4 31.8 22.1 89.4 14.5 13.4 32.4 42.8 112.3 27.3 42.1 29.3 35.5 21.5 95.9 89.8 27.5 24.4 46.5 59.6 11.2 21.5 49.1 19.6 104.0 43.3 19.8 33.0 96.0 99.5 25.9 25.5 23.0 72.5 37.2 21.2 10.3 40.0 111.7 19.7 40.2 32.3 52.0 38.1 78.7 47.7 32.3 66.9 33.8 29.5 48.7 KDM4C "GASC1, JMJD2C, KIAA0780, TDRD14C" ENSG00000107077 "Lysine demethylase 4C" Q9H3R0 9 6720863-7175648 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 206.9;Inhibitory neurons: 235.9;Microglial cells: 148.0;Oligodendrocyte precursor cells: 189.0;Oligodendrocytes: 347.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069357 Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA069357: AB_2686128" "unprognostic (1.56e-2)" "unprognostic (1.91e-2)" "unprognostic (4.38e-2)" "unprognostic (1.38e-1)" "unprognostic (3.52e-1)" "unprognostic (4.36e-2)" "unprognostic (2.50e-2)" "unprognostic (6.89e-3)" "unprognostic (2.37e-1)" "unprognostic (2.34e-2)" "unprognostic (3.65e-2)" "unprognostic (2.03e-2)" "unprognostic (1.92e-1)" "unprognostic (7.87e-3)" "unprognostic (1.21e-1)" "unprognostic (2.23e-2)" "unprognostic (1.64e-3)" 10.0 9.6 9.8 12.8 12.0 30.1 11.3 30.6 11.5 10.2 13.5 13.7 13.1 10.4 11.8 10.1 10.3 9.7 7.8 9.9 11.1 8.7 11.1 10.6 19.1 13.8 11.7 11.5 16.1 17.8 11.8 8.9 13.3 9.9 16.1 28.9 11.6 8.8 8.3 15.2 14.4 10.8 9.7 13.9 15.1 9.8 11.9 23.6 13.4 6.0 18.8 10.3 10.7 16.4 17.2 9.8 4.0 6.0 13.4 14.3 11.8 7.6 9.6 8.5 8.1 11.3 9.1 20.1 4.6 10.3 8.7 5.1 8.6 12.8 11.1 60.6 7.4 27.9 13.8 15.1 12.4 10.8 18.5 12.5 8.4 6.7 14.0 21.1 10.4 16.4 4.7 13.4 9.3 8.3 18.0 40.4 7.0 18.0 3.8 10.8 3.4 12.9 12.3 9.2 14.0 8.3 7.1 12.7 6.8 10.7 6.6 17.5 11.0 8.4 4.0 9.9 7.5 10.2 8.1 21.3 8.2 10.0 3.3 7.5 7.1 13.5 9.6 7.7 11.2 12.1 10.4 11.2 9.6 13.8 11.3 8.8 1.6 11.2 13.1 3.7 10.0 8.0 9.8 12.0 30.6 11.5 9.9 11.1 13.8 11.7 13.3 9.7 11.9 16.4 11.3 6.4 14.4 110.4 40.6 19.9 7.9 10.5 18.8 22.6 11.2 8.0 9.2 11.5 9.2 7.3 45.9 5.2 22.7 10.3 3.9 7.0 84.8 10.0 12.2 9.4 9.7 42.1 206.9 6.2 5.3 6.9 34.7 16.8 8.8 6.0 6.8 13.0 6.7 11.8 235.9 14.7 6.1 10.0 19.4 83.3 9.6 16.5 7.2 148.0 15.0 3.3 19.6 189.0 347.2 7.6 9.5 9.4 27.1 6.2 14.1 4.0 10.8 28.3 13.1 7.3 7.6 6.6 5.4 14.4 23.9 5.9 28.2 6.2 8.1 8.0 KIAA0513 ENSG00000135709 KIAA0513 O60268 16 85027751-85094230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.3" "Cell type enhanced" "Detected in many" "Early spermatids: 50.2;Excitatory neurons: 53.5;Inhibitory neurons: 53.3;Late spermatids: 199.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 25.8;monocytes: 23.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012866, HPA014431" Enhanced Uncertain Nucleoplasm,Cytosol NA NA 67000 "Cluster 18: Basophils - Vesicular transport" "Cluster 6: Brain - Smell perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Cytosol" "HPA012866: AB_1852321, HPA014431: AB_1852322" "unprognostic (1.98e-2)" "unprognostic (2.47e-2)" "unprognostic (2.35e-1)" "unprognostic (1.69e-2)" "unprognostic (1.49e-2)" "unprognostic (9.37e-3)" "unprognostic (2.90e-2)" "unprognostic (8.56e-2)" "unprognostic (1.38e-1)" "unprognostic (4.85e-2)" "prognostic favorable (1.72e-5)" "unprognostic (7.52e-2)" "unprognostic (1.94e-3)" "unprognostic (7.88e-2)" "unprognostic (4.00e-1)" "unprognostic (2.33e-2)" "unprognostic (2.34e-1)" 5.4 11.3 23.5 9.9 35.8 17.1 2.5 35.8 63.3 7.7 0.0 11.0 4.6 5.2 2.7 7.7 3.3 4.7 4.6 41.2 3.3 3.6 2.5 7.5 5.9 12.1 2.6 2.7 15.2 4.1 32.6 3.9 2.6 9.2 6.1 9.2 6.9 4.8 10.2 10.6 6.8 5.6 0.8 8.2 10.8 5.8 2.8 2.8 2.4 3.7 6.6 14.9 6.4 27.4 6.7 7.1 4.7 6.8 8.6 6.4 1.2 6.6 10.4 9.2 5.3 3.2 3.1 2.2 2.8 8.0 5.6 5.8 4.4 10.5 5.7 4.9 3.6 4.3 1.9 1.7 4.1 0.5 5.9 11.9 5.5 10.6 1.4 3.9 5.0 4.6 19.1 5.4 8.3 10.5 0.8 1.8 4.6 7.8 5.6 0.8 6.0 1.4 8.7 4.8 13.7 2.1 7.7 12.7 3.1 4.7 10.3 1.3 10.0 5.7 4.3 8.7 2.3 8.4 1.6 4.8 7.5 3.3 6.2 24.6 11.1 17.9 1.4 13.4 0.4 0.0 0.9 0.9 4.1 0.1 0.8 0.9 25.8 1.3 23.9 5.9 0.3 5.3 23.5 35.8 35.8 63.3 41.2 3.3 12.1 2.6 2.6 0.8 2.8 27.4 0.9 6.4 5.8 7.5 2.6 4.0 7.8 12.4 2.2 17.9 2.7 1.1 8.3 2.8 15.3 1.8 6.2 0.6 8.0 16.0 0.0 2.8 50.2 2.8 7.5 3.3 11.4 0.4 53.5 4.7 0.8 6.9 10.7 4.9 2.5 1.7 3.3 2.9 6.9 48.8 53.3 8.6 10.2 21.5 4.6 199.5 16.1 30.9 3.6 11.2 24.5 3.1 3.1 8.5 7.0 9.1 7.2 26.7 16.5 15.0 4.8 1.8 23.9 5.4 0.0 5.4 3.4 4.1 4.1 1.2 4.4 3.4 4.6 4.8 5.2 29.8 KIAA2012 ENSG00000182329 KIAA2012 2 202073255-202205188 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 6.9;choroid plexus: 3.1;fallopian tube: 9.2" "Group enriched" "Detected in some" 6 "Early spermatids: 38.9;Endometrial ciliated cells: 12.3;Excitatory neurons: 24.8;Late spermatids: 28.6;Respiratory ciliated cells: 43.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077834 Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 49: Ciliated cells - Cilium organization" "HPA077834: " "unprognostic (1.91e-2)" "unprognostic (3.17e-1)" "unprognostic (2.56e-1)" "unprognostic (5.35e-2)" "unprognostic (2.85e-2)" "unprognostic (3.22e-2)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "unprognostic (7.35e-2)" "unprognostic (6.31e-2)" "unprognostic (7.81e-2)" "unprognostic (6.94e-5)" "unprognostic (1.60e-1)" "unprognostic (9.44e-2)" "unprognostic (3.37e-1)" "unprognostic (9.95e-3)" 0.0 0.0 1.0 0.0 2.0 0.0 0.0 0.1 1.3 0.3 3.1 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 1.9 1.1 0.0 0.9 0.8 0.0 5.6 6.9 0.0 0.0 0.0 0.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.0 0.1 1.3 1.9 1.1 5.6 6.9 3.1 4.9 1.9 0.9 0.2 3.2 0.0 1.0 0.1 0.0 0.3 0.0 0.0 2.9 0.4 0.1 1.0 0.0 1.8 0.0 2.1 0.1 0.2 0.0 0.0 0.0 38.9 12.3 0.6 0.4 0.0 0.0 24.8 0.2 0.1 0.6 0.0 0.6 0.0 0.2 1.1 4.8 0.1 3.3 2.8 0.0 0.0 0.0 0.0 28.6 0.0 0.2 0.0 0.0 0.0 0.3 0.0 1.5 0.9 0.0 0.0 0.0 0.0 0.3 0.2 0.0 43.0 2.4 0.0 0.8 0.2 1.5 3.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 KL ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;kidney: 128.7;parathyroid gland: 135.2" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 123.3" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 2.4;SK-BR-3: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.3;cerebral cortex: 6.7;hippocampal formation: 7.4;medulla oblongata: 4.2" "Secreted to blood" NA NA 510000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 3.3 1.4 0.9 0.8 3.1 0.1 2.5 0.8 1.5 1.8 47.1 2.1 2.7 1.2 8.8 1.1 0.8 1.3 1.1 4.2 1.1 128.7 0.4 3.5 1.0 0.5 0.5 0.1 1.2 135.2 0.3 30.4 0.5 8.0 0.9 0.0 0.8 2.5 0.7 0.6 2.6 1.2 0.6 2.4 2.0 0.5 0.8 0.5 1.3 1.5 0.5 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.1 0.8 1.5 4.2 1.1 0.5 0.5 0.5 0.6 0.8 0.5 15.8 0.0 0.5 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.7 12.9 0.0 0.2 0.0 0.4 5.9 0.0 1.8 0.1 2.5 10.2 16.3 0.4 1.2 0.0 0.1 1.6 0.0 0.1 0.0 0.1 1.1 0.2 2.8 0.0 0.5 1.1 0.0 0.9 1.0 0.8 0.3 1.9 0.0 6.5 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.6 1.8 123.3 0.7 0.0 0.0 1.1 2.3 1.4 0.5 0.0 0.1 0.1 1.1 0.1 1.9 0.1 KLF7 UKLF ENSG00000118263 "Kruppel like factor 7" O75840 2 207074137-207167267 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 95.2;Oligodendrocytes: 160.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003423, HPA030490" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA003423: , HPA030490: AB_10601922" "unprognostic (5.93e-2)" "unprognostic (2.49e-3)" "unprognostic (2.98e-1)" "unprognostic (3.99e-3)" "unprognostic (2.56e-1)" "unprognostic (2.85e-3)" "unprognostic (5.44e-2)" "unprognostic (1.24e-2)" "unprognostic (6.75e-2)" "unprognostic (8.78e-2)" "unprognostic (3.67e-2)" "unprognostic (1.47e-1)" "prognostic favorable (4.26e-4)" "unprognostic (3.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (3.47e-2)" 19.9 8.2 8.2 13.8 15.0 40.3 15.0 19.3 9.1 8.9 0.0 11.4 4.6 16.9 5.9 9.7 10.0 11.8 10.1 8.3 13.4 7.9 7.1 15.2 7.7 20.2 17.0 14.2 5.1 3.0 4.9 5.8 20.9 8.2 5.3 4.7 7.4 7.4 4.9 6.8 10.3 20.9 12.1 10.3 9.1 6.8 17.4 14.3 8.8 7.4 7.3 9.8 9.8 20.3 8.8 6.1 16.3 1.1 5.6 14.4 3.4 10.0 8.0 15.3 6.7 0.1 7.1 0.1 6.3 20.6 26.5 21.5 13.9 46.2 8.2 6.0 0.8 0.2 18.5 3.5 9.7 4.6 6.7 19.3 15.3 10.7 35.0 22.0 18.1 4.6 0.0 8.2 11.8 0.2 5.6 1.7 9.7 0.9 3.0 2.4 4.3 6.4 3.7 6.8 25.0 30.5 8.6 12.0 7.8 13.0 2.0 6.9 35.9 30.3 14.5 12.9 12.0 6.2 4.5 0.0 26.7 3.8 6.1 28.9 9.4 12.3 1.6 12.1 0.6 5.7 8.4 1.6 5.3 7.7 14.3 9.9 40.8 22.9 22.7 2.4 7.7 6.1 8.2 15.0 19.3 9.1 8.3 13.4 20.2 17.0 20.9 12.1 17.4 20.3 95.2 41.7 6.7 74.4 15.8 21.9 23.1 35.0 6.2 9.0 9.9 11.4 17.6 14.3 15.1 9.2 12.5 0.5 6.9 0.4 1.9 22.7 10.2 13.9 33.7 65.8 6.0 2.5 46.4 51.5 0.8 22.0 11.7 17.3 12.0 3.6 79.9 14.7 15.6 11.8 31.1 2.6 34.6 50.0 22.9 5.2 13.7 37.6 3.6 61.8 28.3 7.1 8.2 68.9 160.5 79.9 1.4 10.1 4.3 9.2 14.1 4.3 9.8 8.7 46.0 38.6 42.0 0.8 14.8 8.1 15.3 1.1 7.6 7.9 4.3 9.3 KLHL32 "BKLHD5, KIAA1900" ENSG00000186231 "Kelch like family member 32" Q96NJ5 6 96924620-97140754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 65.2" "Cell type enhanced" "Detected in many" "Astrocytes: 143.7;Excitatory neurons: 168.8;Inhibitory neurons: 143.9;Oligodendrocyte precursor cells: 197.5;Oligodendrocytes: 724.3" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "B-cells: 1.0;T-cells: 2.6" "Cell line enhanced" "Detected in some" "Daudi: 3.3;HDLM-2: 4.5;RPMI-8226: 2.1;SCLC-21H: 1.8;U-266/70: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039150 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039150: AB_2676367" "unprognostic (1.75e-1)" "unprognostic (7.99e-2)" "unprognostic (6.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (5.22e-2)" "unprognostic (5.00e-1)" "unprognostic (3.12e-3)" "unprognostic (5.88e-3)" "unprognostic (1.01e-1)" "unprognostic (1.51e-5)" "unprognostic (5.82e-2)" "unprognostic (6.04e-2)" "unprognostic (7.01e-2)" "unprognostic (1.86e-2)" "unprognostic (7.48e-2)" "unprognostic (4.49e-4)" 0.2 0.9 19.6 0.4 40.7 0.1 0.3 24.7 33.3 0.3 1.7 0.6 0.8 0.2 0.4 0.0 6.4 0.3 0.7 21.6 25.9 1.9 0.6 0.7 0.4 31.2 28.2 0.9 1.3 0.7 1.2 0.0 29.9 0.2 0.9 2.5 0.5 0.2 1.2 0.1 1.1 0.1 25.3 0.3 0.5 1.6 29.1 0.7 0.7 0.3 0.4 0.1 0.1 65.2 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 3.3 0.1 0.0 0.0 0.1 0.3 0.1 0.0 4.5 0.7 0.2 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 1.6 0.0 0.0 0.8 0.2 0.2 0.1 0.1 0.1 0.0 2.1 0.0 0.0 1.8 0.6 0.0 0.0 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.3 0.4 1.3 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.9 1.0 1.7 0.6 0.0 0.7 1.9 2.6 0.0 0.4 0.0 0.0 1.2 0.8 19.6 40.7 24.7 33.3 21.6 25.9 31.2 28.2 29.9 25.3 29.1 65.2 0.2 3.2 0.0 143.7 1.1 0.0 0.3 0.1 0.0 2.5 0.4 0.5 2.6 0.0 0.1 5.5 0.0 0.1 0.2 0.3 3.9 0.2 6.9 7.5 0.1 0.0 11.3 0.0 168.8 0.2 0.0 0.3 1.5 0.2 0.0 3.2 0.4 1.3 0.1 18.5 143.9 4.1 0.0 0.0 0.0 3.3 0.0 0.1 0.0 13.1 0.0 1.1 0.0 197.5 724.3 0.0 0.1 0.0 0.5 0.2 0.5 2.4 15.3 1.1 0.0 0.2 0.1 0.8 1.8 0.0 0.0 0.0 0.7 1.1 0.5 0.0 KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 324.2;skin 1: 239.8;vagina: 186.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 152.1;Club cells: 217.9;Late spermatids: 339.0;Prostatic glandular cells: 234.8;Squamous epithelial cells: 176.4;Suprabasal keratinocytes: 217.1;Urothelial cells: 186.1" "Cancer enhanced" "Detected in many" "prostate cancer: 53.3" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;HaCaT: 41.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026340 Approved "Secreted in other tissues" NA NA 1800000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" 28.4 0.2 0.0 0.4 0.0 0.0 17.1 0.9 0.1 109.8 44.5 1.9 0.7 7.2 2.6 324.2 34.2 59.3 2.0 1.7 0.0 0.3 0.8 18.9 0.0 0.2 0.1 1.6 89.1 0.0 8.8 0.0 0.3 64.9 0.6 0.7 169.5 4.2 1.9 239.8 1.4 0.3 0.0 0.1 113.3 14.4 0.6 2.5 0.4 0.3 27.2 1.4 186.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.4 0.1 13.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.7 0.0 0.2 0.1 0.3 0.0 0.6 0.0 0.2 86.6 10.4 0.0 0.4 106.9 152.1 131.6 13.1 0.2 33.4 35.3 0.8 88.6 217.9 0.0 0.0 0.0 0.0 0.1 0.0 9.2 111.6 4.7 1.1 3.8 20.3 0.0 0.0 130.2 0.0 9.1 91.3 15.6 1.3 0.0 0.0 0.0 0.3 0.0 0.0 10.7 118.0 0.0 11.4 339.0 2.8 1.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 79.4 0.0 0.4 0.5 234.8 0.1 0.0 26.9 1.3 0.0 0.2 7.9 2.1 2.5 176.4 217.1 0.0 1.7 0.0 0.4 186.1 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 118.0;skin 1: 87.1;vagina: 47.2" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 66.0;Suprabasal keratinocytes: 180.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 88.3;CAPAN-2: 112.2;HaCaT: 83.5" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 3200000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" 5.7 0.0 0.1 0.0 0.0 0.0 8.4 0.8 0.7 24.7 0.2 0.0 0.0 0.9 0.4 118.0 13.2 0.1 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.7 0.2 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 17.1 0.1 0.7 87.1 0.0 0.1 0.0 0.2 0.1 1.2 0.2 1.1 0.5 0.0 9.6 0.0 47.2 0.5 88.3 0.0 0.0 0.6 0.0 0.0 12.3 0.0 0.0 0.0 0.0 1.7 112.2 0.0 2.2 0.0 0.1 83.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 10.3 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.7 0.0 0.0 0.7 0.2 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.3 66.0 0.0 0.4 14.8 0.0 13.0 15.6 0.1 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.7 11.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 5.0 1.8 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 2.8 6.2 21.1 180.1 0.0 0.2 0.0 0.2 0.1 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 KMT2E "HDCMC04P, MLL5" ENSG00000005483 "Lysine methyltransferase 2E (inactive)" Q8IZD2 7 105014190-105115019 "Disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Growth arrest, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042866, HPA056125" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies" "HPA042866: , HPA056125: AB_2683044" "unprognostic (1.05e-1)" "unprognostic (6.33e-2)" "unprognostic (6.49e-2)" "unprognostic (4.34e-1)" "unprognostic (1.94e-1)" "unprognostic (4.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.98e-3)" "unprognostic (2.03e-2)" "unprognostic (3.16e-2)" "unprognostic (3.53e-2)" "unprognostic (6.45e-2)" "prognostic unfavorable (3.80e-5)" "unprognostic (1.68e-1)" "unprognostic (1.53e-1)" "unprognostic (3.57e-2)" "unprognostic (1.06e-1)" 23.0 16.4 17.6 28.8 23.6 69.9 22.5 53.6 26.1 28.9 11.6 29.0 22.7 33.4 22.1 22.7 24.8 24.5 21.1 16.9 25.9 18.7 16.4 27.9 31.4 19.0 19.2 43.8 22.8 23.1 11.5 26.8 17.7 24.9 28.5 40.5 25.5 23.0 15.0 30.3 22.3 26.8 14.4 33.4 26.7 18.6 17.1 35.6 27.4 22.9 33.0 27.9 14.3 34.4 35.7 24.8 49.3 43.5 29.3 34.5 12.3 24.3 38.2 21.0 25.5 19.0 30.1 28.8 24.7 30.0 27.7 26.2 27.1 25.7 35.0 45.8 17.4 27.0 31.6 19.2 28.1 39.7 34.8 24.2 23.3 28.6 30.6 38.6 40.2 32.3 39.9 76.9 28.7 26.5 62.1 35.0 17.9 19.1 19.1 53.4 30.3 33.5 23.0 34.5 28.8 36.1 35.7 32.3 20.2 32.8 13.6 23.5 47.2 50.0 33.1 57.5 26.4 61.6 50.8 63.5 34.3 29.5 36.3 246.8 73.2 173.1 118.3 56.2 114.6 153.9 109.7 103.0 53.8 152.0 106.0 100.0 290.3 89.9 94.4 103.2 101.5 71.7 17.6 23.6 53.6 26.1 16.9 25.9 19.0 19.2 17.7 14.4 17.1 34.4 169.3 141.1 158.4 108.4 283.5 146.6 115.5 119.2 118.4 236.4 93.4 81.5 102.9 85.8 124.6 115.8 252.3 40.5 278.0 138.0 35.2 82.2 27.0 77.8 89.3 205.6 100.0 90.5 160.2 68.1 50.4 128.8 91.7 112.4 247.9 78.2 119.2 33.6 60.4 185.1 148.9 96.4 89.5 91.8 348.4 27.3 141.1 152.2 140.5 148.9 147.5 104.1 255.4 189.0 236.2 80.7 102.9 131.7 223.1 149.7 82.6 32.4 78.3 297.5 124.9 136.7 168.3 100.0 76.4 86.1 134.7 65.3 278.3 58.2 115.4 159.9 KMT5A "PR-Set7, SET07, SET8, SETD8" ENSG00000183955 "Lysine methyltransferase 5A" Q9NQR1 12 123383773-123409353 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064495 Supported Nucleoplasm,Cytosol NA Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA064495: AB_2685273" "unprognostic (5.62e-2)" "unprognostic (4.45e-2)" "unprognostic (3.90e-1)" "unprognostic (3.04e-1)" "unprognostic (2.20e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.21e-7)" "unprognostic (3.88e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-2)" "unprognostic (6.13e-2)" "unprognostic (3.44e-1)" "unprognostic (4.75e-3)" "unprognostic (4.27e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.06e-1)" 13.7 10.1 22.6 15.3 22.1 39.2 13.1 20.8 23.2 22.2 18.7 17.7 12.8 21.3 12.9 40.7 21.7 13.6 17.0 22.2 20.6 13.7 14.0 15.5 15.4 22.4 22.7 12.0 19.7 11.4 10.7 16.5 22.9 30.2 14.4 11.7 24.0 19.7 24.4 28.1 15.6 16.7 21.4 16.8 16.9 7.9 23.3 17.9 25.7 15.3 16.6 16.6 25.7 23.9 37.3 24.3 27.8 43.5 18.1 30.9 40.1 57.4 26.3 32.0 26.9 28.8 21.9 84.9 33.1 37.5 11.7 35.8 41.6 21.7 33.3 39.3 45.0 68.8 26.4 15.2 26.5 54.8 18.8 15.1 27.1 34.7 32.8 30.2 26.2 36.4 136.8 38.1 27.5 29.9 58.1 84.9 13.8 34.6 29.0 70.4 22.1 24.1 22.8 43.4 37.9 30.9 51.3 28.3 28.6 23.6 39.6 75.3 32.4 35.2 26.0 42.3 42.3 23.0 25.9 75.9 24.6 29.6 29.9 2.3 1.2 4.3 1.3 2.1 2.7 1.7 1.6 2.1 1.0 1.1 0.9 1.1 1.8 2.3 2.1 2.0 1.5 0.3 22.6 22.1 20.8 23.2 22.2 20.6 22.4 22.7 22.9 21.4 23.3 23.9 34.5 12.8 14.5 0.0 12.7 0.0 17.6 0.0 20.5 20.8 32.0 27.3 0.0 7.2 6.8 27.6 6.2 15.1 22.4 10.4 7.9 9.2 10.1 46.8 43.8 20.7 4.9 62.1 0.0 9.4 16.6 14.7 15.8 41.1 2.5 21.3 30.4 19.5 17.7 3.3 0.0 22.2 0.0 16.8 0.0 3.2 16.1 19.6 0.0 0.0 3.4 28.7 7.2 0.0 0.0 13.6 9.6 42.9 15.9 24.1 14.3 13.1 11.7 17.9 6.6 23.2 19.7 9.7 10.2 38.8 0.0 14.2 14.5 18.4 12.7 22.5 KNSTRN "C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1" ENSG00000128944 "Kinetochore localized astrin (SPAG5) binding protein" Q9Y448 15 40382721-40394246 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.6;thyroid gland: 53.1" "Cell type enhanced" "Detected in many" "Early spermatids: 328.2;Late spermatids: 600.1;Spermatocytes: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042027 Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Mitotic spindle, Centriolar satellite" "Plasma membrane" "HPA042027: AB_10797378" "unprognostic (2.35e-3)" "unprognostic (6.83e-2)" "unprognostic (3.01e-1)" "unprognostic (5.23e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-2)" "unprognostic (1.54e-3)" "unprognostic (2.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.88e-9)" "unprognostic (1.70e-1)" "unprognostic (1.58e-1)" "unprognostic (2.67e-1)" "unprognostic (1.52e-2)" 8.0 6.2 6.3 8.1 7.1 14.1 14.3 7.7 8.6 5.1 4.5 7.9 9.2 6.4 12.3 9.1 5.7 4.4 7.4 7.2 6.2 7.2 12.0 5.8 14.5 6.2 6.2 5.1 5.0 8.4 5.6 10.7 6.5 6.8 10.4 9.0 10.3 7.2 12.2 6.7 6.2 10.2 5.9 7.1 10.2 63.6 6.1 25.6 53.1 12.4 16.1 5.6 5.6 7.7 103.4 47.5 92.7 61.0 20.1 30.9 48.1 69.9 54.0 141.0 123.3 102.6 44.2 39.7 34.8 47.3 112.1 115.7 100.0 64.8 126.5 70.8 48.8 117.7 107.4 65.2 18.9 63.8 58.6 16.1 36.5 71.3 70.6 34.5 80.3 97.6 86.3 66.8 120.0 52.2 55.6 51.2 58.6 87.7 71.2 56.4 69.7 45.7 49.7 42.3 89.9 62.5 58.3 63.3 15.1 55.8 66.5 45.3 41.6 67.5 68.8 69.7 98.3 56.5 98.6 70.5 41.8 84.0 56.5 13.2 17.6 17.4 7.9 24.3 6.8 9.5 5.7 7.0 18.4 11.2 5.4 5.5 9.7 9.8 47.8 12.7 9.4 7.1 6.3 7.1 7.7 8.6 7.2 6.2 6.2 6.2 6.5 5.9 6.1 7.7 2.4 9.6 1.1 2.6 4.1 2.2 2.9 7.6 3.4 8.2 4.2 3.4 7.3 1.5 5.4 0.0 8.4 25.2 2.5 1.9 3.9 8.5 328.2 5.9 4.9 3.7 2.4 34.3 5.1 9.3 40.8 5.2 5.6 4.4 1.3 16.9 3.6 8.0 21.6 5.0 4.9 5.3 14.2 9.8 2.0 600.1 9.0 8.2 3.6 4.7 8.0 8.5 6.2 2.0 4.3 12.3 0.5 7.2 12.6 4.9 2.8 5.8 7.2 8.5 0.0 3.7 6.5 145.7 19.2 7.0 1.4 21.1 5.1 8.5 6.4 3.0 KPNA6 "FLJ11249, IPOA7, KPNA7, MGC17918" ENSG00000025800 "Karyopherin subunit alpha 6" O60684 1 32108056-32176563 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 294.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018863 Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA018863: AB_1852632" "unprognostic (8.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.95e-1)" "unprognostic (3.30e-2)" "unprognostic (8.35e-2)" "unprognostic (7.34e-2)" "prognostic unfavorable (9.28e-5)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.51e-2)" "unprognostic (3.18e-1)" "unprognostic (5.32e-2)" "unprognostic (1.73e-2)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (1.80e-1)" "unprognostic (1.57e-2)" 14.2 15.4 12.8 11.0 13.9 20.5 13.1 12.4 15.1 15.4 12.7 17.7 8.8 17.1 12.8 18.8 14.2 8.8 22.0 13.8 17.2 13.8 15.8 15.1 11.1 15.7 16.3 13.4 13.4 24.6 14.3 16.6 18.2 13.9 13.0 17.1 13.4 14.3 39.3 18.5 12.5 17.8 12.0 12.0 14.8 20.2 14.6 12.8 13.5 23.7 14.8 15.6 15.6 14.5 32.0 24.8 21.6 28.0 32.5 28.4 25.3 25.2 29.5 36.0 34.5 27.8 33.9 26.5 29.1 45.6 21.6 26.7 33.5 38.5 45.6 27.0 18.4 27.4 36.4 22.6 28.7 30.4 21.5 28.9 35.8 44.6 42.3 30.3 38.1 20.5 27.0 23.7 34.4 17.5 24.6 17.3 50.5 20.6 18.3 24.5 31.0 21.7 31.4 28.9 20.7 17.4 45.8 27.1 25.0 52.6 19.2 15.9 44.5 33.1 22.7 43.8 36.6 16.9 20.7 20.3 36.3 27.8 32.4 3.2 7.4 7.2 7.7 9.1 7.5 5.3 6.5 6.0 6.0 6.1 7.4 7.2 4.2 3.8 9.9 6.7 7.3 5.3 12.8 13.9 12.4 15.1 13.8 17.2 15.7 16.3 18.2 12.0 14.6 14.5 27.9 41.7 41.5 33.0 36.1 63.6 36.9 37.6 22.2 48.6 44.7 26.7 32.7 37.1 32.4 29.5 58.4 45.4 42.4 29.5 17.6 36.2 294.2 41.0 44.6 40.4 46.1 52.8 62.5 31.6 41.6 35.7 25.5 49.3 13.9 31.3 36.0 77.3 30.4 52.2 58.4 36.0 24.4 36.8 44.8 65.2 34.2 29.3 24.9 30.0 41.4 29.0 47.4 40.7 54.3 46.1 26.4 40.6 24.1 56.7 25.3 33.2 48.2 44.7 32.9 53.1 36.7 78.7 56.2 31.2 85.1 135.7 31.7 31.8 35.6 59.0 KREMEN2 "KRM2, MGC10791" ENSG00000131650 "Kringle containing transmembrane protein 2" Q8NCW0 16 2964216-2968383 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 4.1;skin 1: 7.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.1;Basal squamous epithelial cells: 23.3;Intestinal goblet cells: 14.0;Rod photoreceptor cells: 10.9;Spermatocytes: 9.7;Spermatogonia: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.2;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cell line enhanced" "Detected in many" "HMC-1: 29.3;MCF7: 15.0;RPMI-8226: 28.8;T-47d: 14.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA003223 Uncertain Approved Nucleoli "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoli "HPA003223: AB_1079217" "unprognostic (8.36e-2)" "unprognostic (4.65e-1)" "unprognostic (6.24e-3)" "unprognostic (4.61e-2)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (4.02e-3)" "prognostic unfavorable (8.98e-4)" "unprognostic (3.34e-2)" "unprognostic (1.57e-2)" "unprognostic (8.03e-2)" "unprognostic (8.57e-2)" "unprognostic (7.79e-12)" "unprognostic (6.69e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-2)" "unprognostic (6.58e-3)" 0.1 0.1 0.7 0.3 0.7 0.7 0.1 0.0 0.6 1.5 0.0 0.3 0.1 0.1 0.1 2.0 0.3 0.1 0.0 1.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.0 4.1 0.4 0.0 0.3 7.7 0.6 0.0 0.0 0.2 0.2 1.7 0.0 2.1 0.0 0.0 0.8 0.0 0.5 0.1 1.8 1.1 0.4 10.2 0.0 0.0 1.5 0.6 0.0 0.0 0.0 4.2 1.5 7.8 2.1 0.0 1.1 8.6 1.3 0.7 0.0 1.1 1.2 0.5 2.9 2.6 0.0 0.6 29.3 0.2 0.0 0.0 0.1 0.9 0.0 0.8 3.3 2.9 0.0 15.0 1.8 3.5 2.9 3.0 2.2 4.7 11.8 28.8 0.1 0.3 2.9 1.8 2.0 4.7 5.2 0.4 14.9 2.8 0.2 0.9 12.2 1.0 0.7 5.3 1.3 4.7 0.4 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.7 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 1.4 14.1 0.9 0.3 23.3 0.4 1.0 0.9 0.9 0.0 0.0 0.0 6.2 0.2 0.0 1.1 0.0 0.1 0.7 0.4 0.1 0.1 0.0 0.0 0.4 2.7 1.8 0.1 0.0 0.9 4.5 0.0 0.0 0.0 0.1 0.0 0.1 14.0 0.0 0.0 0.6 0.6 0.0 0.2 3.6 0.0 0.1 0.5 0.0 0.0 0.0 0.2 1.3 0.0 0.1 2.1 0.5 0.0 0.0 10.9 0.0 0.0 0.3 9.7 18.0 1.2 5.5 0.1 0.6 0.0 0.5 0.4 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KRT2 "KRT2A, KRTE" ENSG00000172867 "Keratin 2" P35908 12 52644558-52652211 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "skin 1: 4660.3" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 265.4" "Cancer enriched" "Detected in some" 5 "melanoma: 23.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Cell line enhanced" "Detected in single" "HEL: 2.0" "Group enriched" "Detected in some" 6 "amygdala: 1.7;hippocampal formation: 2.7" "Not detected" "Not detected" "HPA006299, CAB037321" Enhanced Approved "Golgi apparatus,Intermediate filaments,Cytosol" NA NA 9700000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 3: HMC-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments, Cytosol" "Golgi apparatus" "CAB037321: , HPA006299: AB_1079180" "unprognostic (1.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.56e-1)" "unprognostic (8.47e-3)" "unprognostic (1.69e-2)" "unprognostic (1.84e-1)" "unprognostic (3.59e-1)" "unprognostic (2.12e-1)" "unprognostic (4.76e-2)" "unprognostic (3.56e-7)" "unprognostic (6.43e-2)" "unprognostic (5.98e-3)" "unprognostic (6.69e-2)" "unprognostic (3.46e-1)" 3.0 0.5 0.0 0.1 0.0 1.0 81.9 0.0 0.0 0.8 0.0 0.9 1.6 0.4 0.3 1.1 0.1 0.0 1.7 0.0 0.0 0.5 1.2 1.0 0.5 0.0 0.0 0.5 1.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 1.6 0.0 47.8 4660.3 0.8 0.0 0.0 0.5 0.7 1.0 0.0 6.8 0.8 0.0 6.1 0.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.1 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 9.5 0.0 0.0 0.1 8.8 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 265.4 0.1 1.0 0.0 0.6 0.1 KRT27 KRT25C ENSG00000171446 "Keratin 27" Q7Z3Y8 17 40776808-40782550 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "skin 1: 71.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.0;Endothelial cells: 1.5;Hepatic stellate cells: 2.2;Melanocytes: 8.8;Muller glia cells: 3.0;Spermatogonia: 2.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.9;thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "EFO-21: 1.4" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "hippocampal formation: 80.6" HPA055114 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA055114: AB_2682700" "unprognostic (1.13e-1)" "unprognostic (1.87e-1)" "unprognostic (2.18e-1)" "unprognostic (5.75e-4)" "unprognostic (5.11e-2)" "unprognostic (3.08e-2)" "unprognostic (8.41e-2)" "unprognostic (4.16e-1)" "unprognostic (1.53e-1)" "unprognostic (4.90e-1)" "unprognostic (1.56e-1)" "unprognostic (5.64e-3)" 1.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.4 0.1 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 8.8 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 2.3 0.0 0.4 0.3 0.0 0.0 0.0 0.0 KRT3 "CK3, K3" ENSG00000186442 "Keratin 3" P12035 12 52789685-52796117 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 3.0;salivary gland: 10.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 0.7;head and neck cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 9.4;HMC-1: 5.6" "Region enhanced" "Detected in single" "cerebral cortex: 1.7" NA NA 280000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.03e-1)" "unprognostic (2.68e-2)" "unprognostic (2.42e-2)" "unprognostic (2.75e-1)" "unprognostic (9.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (1.54e-2)" "unprognostic (3.89e-2)" "unprognostic (2.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.73e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.3 0.8 0.0 0.0 0.0 0.0 KRT32 "Ha-2, KRTHA2" ENSG00000108759 "Keratin 32" Q14532 17 41459513-41467386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "esophagus: 5.9;skin 1: 19.5" "Group enriched" "Detected in some" 6 "Basal squamous epithelial cells: 21.6;Squamous epithelial cells: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTERT-RPE1: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 210000000 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.39e-2)" "unprognostic (3.29e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.13e-1)" "unprognostic (3.46e-1)" "unprognostic (2.32e-2)" "unprognostic (2.67e-3)" "unprognostic (2.72e-9)" "unprognostic (1.31e-2)" "unprognostic (1.77e-1)" 0.6 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.1 0.0 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.8 21.6 0.0 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.4 0.0 0.4 KRT33B "Ha-3II, KRTHA3B" ENSG00000131738 "Keratin 33B" Q14525 17 41363498-41369813 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "skin 1: 82.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 2.9;Ionocytes: 2.0" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "BJ: 4.3;BJ hTERT+ SV40 Large T+ RasG12V: 1.1" HPA055194 Supported NA NA 350000000 "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA055194: AB_2682733" "unprognostic (3.34e-2)" "unprognostic (5.19e-2)" "unprognostic (3.04e-1)" "unprognostic (1.55e-2)" "unprognostic (6.28e-2)" 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 82.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 KRT34 "Ha-4, KRTHA4" ENSG00000131737 "Keratin 34" O76011 17 41377650-41382403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skin 1: 66.6" "Group enriched" "Detected in some" 8 "Early spermatids: 5.4;Late spermatids: 15.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "BJ: 201.8" "Not detected" "Not detected" "HPA055194, HPA072208" Enhanced Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA055194: AB_2682733, HPA072208: AB_2686494" "unprognostic (2.52e-1)" "unprognostic (2.14e-1)" "unprognostic (9.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.86e-3)" "unprognostic (5.12e-7)" "unprognostic (3.84e-2)" 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 1.1 1.8 0.0 1.6 0.0 0.0 0.0 0.1 1.9 0.0 201.8 8.8 23.5 46.4 0.0 0.1 0.0 0.0 25.1 0.1 0.0 0.0 0.0 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 8.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.1 26.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.0 0.3 0.0 0.0 KRT35 "Ha-5, KRTHA5" ENSG00000197079 "Keratin 35" Q92764 17 41476689-41481140 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 59.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025750, HPA078713" Enhanced Approved "Intermediate filaments" NA NA 220000000 "Cluster 61: Skin - Cornification" "Intermediate filaments" "HPA025750: , HPA078713: " 2.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 59.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 KRT5 "EBS2, KRT5A" ENSG00000186081 "Keratin 5" P13647 12 52514575-52520530 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 5865.0;skin 1: 5885.4;vagina: 2150.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5870.1;Basal prostatic cells: 1037.6;Basal squamous epithelial cells: 1571.3;Squamous epithelial cells: 4370.9;Suprabasal keratinocytes: 2020.2" "Group enriched" "Detected in many" 4 "cervical cancer: 1863.2;head and neck cancer: 3340.4" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 326 "plasmacytoid DC: 32.6" "Lineage enriched" "Detected in single" 326 "dendritic cells: 32.6" "Group enriched" "Detected in some" 7 "HaCaT: 3368.0;HBEC3-KT: 5990.5;hTCEpi: 13326.8" "Region enriched" "Detected in many" 8 "spinal cord: 36.4" "CAB000027, CAB000129, HPA059479" Enhanced Approved "Intermediate filaments" NA NA 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000027: AB_2281083, CAB000129: , HPA059479: AB_2684034" "prognostic favorable (1.27e-4)" "unprognostic (9.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.29e-2)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" "unprognostic (7.20e-2)" "unprognostic (2.82e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-2)" "unprognostic (1.73e-1)" "unprognostic (6.01e-7)" "unprognostic (3.46e-2)" "unprognostic (5.56e-2)" "unprognostic (7.96e-2)" "unprognostic (2.81e-3)" 10.0 1.7 0.2 1.8 0.8 4.6 252.5 0.7 0.5 826.2 58.9 1.9 0.0 2.0 97.2 5865.0 12.5 2.0 3.8 1.7 0.0 1.3 3.5 6.4 3.0 0.1 0.0 2.2 4.7 0.1 8.2 2.0 0.1 125.8 0.0 0.0 880.3 100.0 9.9 5885.4 1.8 0.6 0.1 1.7 5.0 2.1 0.6 527.1 3.0 0.3 648.6 93.2 2150.9 0.4 50.6 0.0 0.0 0.0 2.3 0.2 0.8 0.0 0.0 0.0 0.0 1.0 0.3 2.4 0.5 0.2 0.0 3368.0 0.2 5990.5 0.2 0.0 0.0 0.2 0.1 0.0 0.6 1.4 2.8 0.3 13326.8 0.6 1049.7 0.0 0.8 0.0 1.8 4.0 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.2 1.0 1.2 0.8 0.9 0.0 0.1 1.2 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.9 0.5 0.2 10.1 1.0 0.9 4.0 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.1 0.2 0.8 0.7 0.5 1.7 0.0 0.1 0.0 0.1 0.1 0.6 0.4 1.7 0.0 1.1 0.0 0.4 5870.1 1037.6 627.1 1571.3 0.0 43.6 226.2 0.5 0.0 180.7 0.0 0.0 0.0 39.8 0.0 0.0 0.5 0.8 31.3 1.2 26.4 0.0 0.0 0.5 0.0 0.0 29.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 273.6 0.1 0.6 7.3 286.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 22.2 789.7 0.0 0.1 34.8 0.0 0.0 0.2 33.4 0.0 0.0 4370.9 2020.2 0.0 17.8 0.0 0.1 459.8 KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 2523.3;esophagus: 7338.5;vagina: 4945.4" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 674.0;Club cells: 200.5;Squamous epithelial cells: 876.0;Suprabasal keratinocytes: 151.4;Urothelial cells: 306.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3892.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "hTCEpi: 9761.7" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 4500000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (8.10e-3)" "unprognostic (2.11e-1)" "unprognostic (2.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (2.43e-1)" "unprognostic (3.73e-2)" "unprognostic (1.31e-3)" "unprognostic (1.29e-1)" "unprognostic (2.89e-9)" "unprognostic (8.80e-2)" "unprognostic (7.20e-2)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" 3.1 1.5 0.0 1.9 0.0 0.1 6.9 0.0 0.0 2523.3 0.0 1.2 0.0 1.3 0.0 7338.5 9.1 0.9 1.8 0.0 0.0 1.1 2.6 3.4 0.0 0.0 0.0 2.3 3.3 0.0 3.1 8.8 0.0 5.0 0.0 0.0 1025.5 0.0 1.9 480.0 1.3 0.4 0.0 1.4 4.9 1.0 0.0 33.6 1.5 0.0 628.6 19.7 4945.4 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 3.9 0.0 0.0 1143.8 0.0 2414.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.5 0.6 0.3 9761.7 0.2 306.7 0.0 0.3 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 14.0 0.3 0.1 0.5 0.0 0.3 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.2 0.2 0.4 0.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.5 79.0 674.0 12.0 0.0 0.6 1.7 0.0 0.0 200.5 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 2.6 0.2 0.8 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 5.5 0.0 0.0 0.7 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 100.4 0.0 0.0 24.5 0.0 0.0 0.0 11.8 0.0 0.0 876.0 151.4 0.0 1.7 0.0 0.1 306.8 KRT6B KRTL1 ENSG00000185479 "Keratin 6B" P04259 12 52446651-52452146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 228.2;esophagus: 934.5;skin 1: 285.1;vagina: 229.6" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 217.5" "Group enriched" "Detected in many" 5 "head and neck cancer: 1424.3;melanoma: 472.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 148.7" "CAB000130, HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000130: , HPA045697: AB_2679422, HPA061168: AB_2684440" "prognostic favorable (9.44e-4)" "unprognostic (3.27e-2)" "unprognostic (1.93e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-2)" "unprognostic (2.07e-3)" "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (5.77e-2)" "unprognostic (9.63e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (9.52e-4)" 0.9 0.2 0.0 2.0 0.0 0.1 16.2 0.0 0.0 228.2 0.0 0.5 0.0 0.1 0.0 934.5 0.2 0.2 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 168.6 0.0 0.3 285.1 0.2 0.0 0.0 0.1 0.7 0.2 0.0 2.1 0.1 0.0 74.3 0.2 229.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 27.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.7 1.1 0.0 0.1 13.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 20.6 1.8 40.4 0.0 0.0 28.7 16.8 0.1 0.0 16.3 0.0 0.0 0.0 0.9 0.3 0.0 46.2 1.8 0.0 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 1.7 1.3 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.6 0.0 0.0 2.8 0.0 0.0 0.0 1.4 0.0 0.2 217.5 32.7 0.0 0.3 0.0 0.6 5.9 KRT6C KRT6E ENSG00000170465 "Keratin 6C" P48668 12 52468516-52473805 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 211.7;esophagus: 799.4;vagina: 333.5" "Cell type enriched" "Detected in some" 60 "Squamous epithelial cells: 234.3" "Group enriched" "Detected in many" 5 "head and neck cancer: 564.7;melanoma: 242.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 94.1" "HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (3.18e-2)" "unprognostic (6.26e-3)" "unprognostic (6.63e-2)" "unprognostic (1.54e-3)" "unprognostic (6.97e-2)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (3.25e-2)" "unprognostic (2.24e-1)" "unprognostic (2.84e-1)" "unprognostic (4.50e-2)" 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 211.7 0.0 0.1 0.0 0.1 0.0 799.4 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 144.3 0.0 0.1 24.7 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.0 0.1 0.0 9.5 0.1 333.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 94.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.2 1.3 2.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 234.3 2.4 0.0 0.0 0.0 0.2 3.9 KRT73 "K6IRS3, KRT6IRS3" ENSG00000186049 "Keratin 73" Q86Y46 12 52607570-52618559 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 17.0" "Cell type enriched" "Detected in some" 5 "NK-cells: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "naive CD4 T-cell: 8.8;naive CD8 T-cell: 3.1" "Lineage enriched" "Detected in single" 13 "T-cells: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA044031 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 63: NK-cells & T-cells - Immune response" "HPA044031: AB_10963434" "unprognostic (2.23e-3)" "unprognostic (6.54e-2)" "unprognostic (3.05e-1)" "unprognostic (2.12e-3)" "unprognostic (2.11e-3)" "unprognostic (4.94e-1)" 0.3 0.0 0.0 0.7 0.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 17.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.0 8.8 3.1 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 7.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 KRT77 KRT1B ENSG00000189182 "Keratin 77" Q7Z794 12 52689626-52703524 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 273.0" "Cell type enriched" "Detected in some" 8 "Suprabasal keratinocytes: 20.2" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 36 "HaCaT: 3.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045934 Enhanced Approved "Nuclear membrane,Plasma membrane" NA NA 1200000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Nuclear membrane, Plasma membrane" "HPA045934: AB_10960065" "unprognostic (3.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-1)" "unprognostic (2.61e-1)" "unprognostic (2.11e-1)" "unprognostic (2.06e-1)" 0.6 0.0 0.0 0.0 0.0 0.1 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 273.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 20.2 0.0 0.0 0.0 0.0 0.0 KRT82 "Hb-2, KRTHB2" ENSG00000161850 "Keratin 82" Q9NSB4 12 52393931-52406335 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "skin 1: 12.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058715, HPA067230" Enhanced NA NA 29000000 "Cluster 61: Skin - Cornification" "HPA058715: AB_2683798, HPA067230: AB_2685807" "unprognostic (3.04e-1)" "unprognostic (3.59e-3)" 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 KRT86 "Hb6, KRTHB6, MNX" ENSG00000170442 "Keratin 86" O43790 12 52249300-52309163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "skin 1: 150.5" "Group enriched" "Detected in many" 4 "dendritic cells: 33.1;Early spermatids: 35.5;Late spermatids: 24.3;NK-cells: 11.3;T-cells: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 9 "basophil: 87.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 87.5" "Cell line enhanced" "Detected in many" "A-431: 24.9;A549: 25.7;MCF7: 51.6;RPMI-8226: 32.5;U-251 MG: 14.5" "HPA039798, HPA049778" Supported Approved Cytosol NA NA 160000000 "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA039798: AB_10674986, HPA049778: AB_2680877" "unprognostic (4.52e-2)" "unprognostic (6.83e-2)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (2.61e-2)" "unprognostic (6.49e-2)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (7.22e-2)" 1.2 0.5 0.5 0.2 0.7 2.6 0.5 0.0 0.5 0.2 0.0 0.5 0.4 0.4 0.5 0.1 0.7 0.4 0.1 0.8 0.2 0.2 0.1 0.7 0.0 0.3 0.4 0.1 2.1 0.1 0.1 0.4 0.4 0.3 0.0 0.1 3.8 0.3 0.3 150.5 0.3 0.1 0.2 0.1 0.2 4.0 0.5 0.2 4.1 0.0 0.1 0.8 0.2 1.2 24.9 25.7 0.0 0.0 0.0 0.0 0.3 0.9 0.7 0.3 0.1 0.3 1.3 0.0 1.1 0.0 0.5 1.5 0.0 4.5 0.1 10.9 0.0 0.0 5.4 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.5 12.7 0.0 0.0 0.0 1.8 0.0 51.6 0.0 3.0 0.1 0.2 6.1 0.0 0.0 32.5 0.4 3.2 2.9 0.0 4.5 2.0 2.0 0.0 1.4 0.0 0.8 0.0 1.3 0.1 14.5 0.0 0.0 0.0 0.0 5.3 0.0 87.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.5 0.5 0.7 0.0 0.5 0.8 0.2 0.3 0.4 0.4 0.2 0.5 1.2 0.1 0.0 0.6 0.0 0.3 0.6 2.9 2.0 0.0 0.4 2.8 3.4 0.4 2.8 3.1 0.0 0.0 0.1 33.1 0.2 0.0 2.1 35.5 3.6 0.8 0.2 0.0 0.0 0.5 5.1 1.6 0.3 1.1 4.9 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.0 0.0 1.1 24.3 0.3 0.3 1.8 0.0 0.0 0.2 11.3 0.0 0.5 2.9 0.0 0.0 2.1 2.7 0.0 0.6 1.9 0.3 0.0 1.0 0.4 0.8 0.4 0.0 0.1 1.2 14.2 0.0 0.0 3.5 KRTAP1-4 KAP1.4 ENSG00000204887 "Keratin associated protein 1-4" P0C5Y4 17 41029697-41030104 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "skin 1: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 67: Proximal tubular cells - Tubular reabsorption" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP1-5 KAP1.5 ENSG00000221852 "Keratin associated protein 1-5" Q9BYS1 17 41026026-41027208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "skin 1: 79.0" "Group enriched" "Detected in some" 8 "Basal prostatic cells: 4.1;Syncytiotrophoblasts: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 3.9;BJ: 17.1;fHDF/TERT166: 10.6;HDLM-2: 6.5;U-138 MG: 4.6;U-87 MG: 3.4" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (1.76e-1)" "unprognostic (2.96e-2)" "unprognostic (2.24e-2)" "unprognostic (2.55e-1)" "unprognostic (1.90e-1)" "unprognostic (9.98e-2)" "unprognostic (1.80e-2)" "unprognostic (5.60e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 79.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.7 0.0 0.1 0.0 0.2 KRTAP19-1 KAP19.1 ENSG00000184351 "Keratin associated protein 19-1" Q8IUB9 21 30479706-30480367 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 116 "skin 1: 16.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 19 "melanoma: 17.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HEK 293: 20.8" NA NA "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "unprognostic (2.36e-2)" "unprognostic (8.67e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 KRTAP19-3 KAP19.3 ENSG00000244025 "Keratin associated protein 19-3" Q7Z4W3 21 30491462-30492013 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 89 "skeletal muscle: 6.7;skin 1: 15.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP19-5 KAP19.5 ENSG00000186977 "Keratin associated protein 19-5" Q3LI72 21 30501657-30502141 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "skin 1: 31.6" "Cell type enriched" "Detected in single" 22 "Syncytiotrophoblasts: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HEK 293: 4.3" NA NA 1600000 "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 KRTAP19-6 KAP19.6 ENSG00000186925 "Keratin associated protein 19-6" Q3LI70 21 30541535-30541864 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP19-7 KAP19.7 ENSG00000244362 "Keratin associated protein 19-7" Q3SYF9 21 30560875-30561314 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP20-1 KAP20.1 ENSG00000244624 "Keratin associated protein 20-1" Q3LI63 21 30616425-30616699 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP20-2 KAP20.2 ENSG00000184032 "Keratin associated protein 20-2" Q3LI61 21 30635206-30635619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "skin 1: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 23: Spermatids - Flagellum & Golgi organization" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP3-3 KAP3.3 ENSG00000212899 "Keratin associated protein 3-3" Q9BYR6 17 40993430-40994164 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 209 "skin 1: 129.3" "Cell type enriched" "Detected in single" 4 "Enteroendocrine cells: 1.8" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042992 Supported NA NA "Cluster 61: Skin - Cornification" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA042992: AB_2678258" 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 129.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-16 "KAP4A, KRTAP4-16P, KRTAP4P1" ENSG00000241241 "Keratin associated protein 4-16" 17 41101502-41102209 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.7 0.3 0.4 0.6 0.3 0.6 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP5-6 KRTAP5.6 ENSG00000205864 "Keratin associated protein 5-6" Q6L8G9 11 1697195-1697755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.0;skin 1: 1.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "liver cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 85: Liver - Metabolism" "prognostic favorable (6.04e-5)" "unprognostic (3.70e-1)" "unprognostic (2.93e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP6-1 "C21orf103, KAP6.1" ENSG00000184724 "Keratin associated protein 6-1" Q3LI64 21 30613431-30613930 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "skin 1: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP7-1 KAP7.1 ENSG00000274749 "Keratin associated protein 7-1" Q8IUC3 21 30829039-30829759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 104 "skin 1: 25.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "urothelial cancer: 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 61: Skin - Cornification" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP8-1 KAP8.1 ENSG00000183640 "Keratin associated protein 8-1" Q8IUC2 21 30812697-30813274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 86 "skin 1: 61.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "urothelial cancer: 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 34: Spermatids - Unknown function" 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 61.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-1 "KAP9.1, KRTAP9L3" ENSG00000240542 "Keratin associated protein 9-1" A8MXZ3 17 41189887-41190639 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 46 "HDLM-2: 4.5" NA NA "Cluster 44: HDLM-2 - Immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KTI12 "MGC20419, SBBI81, TOT4" ENSG00000198841 "KTI12 chromatin associated homolog" Q96EK9 1 52032103-52033810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031203, HPA031204, HPA031205" Approved Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Cytoplasmic bodies" "HPA031203: AB_2732464, HPA031204: AB_10600110, HPA031205: AB_10611380" "unprognostic (6.14e-2)" "unprognostic (9.45e-2)" "unprognostic (1.19e-3)" "unprognostic (3.36e-3)" "unprognostic (4.18e-1)" "unprognostic (1.83e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.74e-1)" "unprognostic (2.94e-1)" "unprognostic (3.72e-2)" "unprognostic (4.06e-2)" "unprognostic (8.08e-3)" "unprognostic (6.59e-2)" "unprognostic (3.36e-3)" "unprognostic (2.39e-1)" "unprognostic (3.59e-2)" "unprognostic (1.64e-2)" 7.5 10.2 4.2 6.9 4.0 16.7 5.9 4.5 4.4 4.5 4.9 6.5 4.9 7.3 4.7 5.8 6.9 3.8 5.1 4.0 5.0 4.9 6.8 4.2 8.7 4.5 4.1 9.2 6.8 3.9 6.4 4.2 4.1 4.0 4.0 2.5 4.0 4.7 4.6 5.5 7.6 4.7 4.1 8.5 7.1 7.2 4.9 6.6 4.0 3.5 7.6 5.5 3.8 4.4 14.0 13.4 5.3 12.5 17.8 14.8 16.6 13.9 17.0 20.1 17.1 15.2 6.7 16.0 15.3 14.5 29.8 15.6 18.7 16.4 13.9 16.5 20.9 16.6 14.6 14.9 12.3 23.8 15.7 13.9 12.5 16.0 8.6 8.7 13.8 14.0 25.2 7.7 17.1 11.1 17.5 26.7 10.3 12.2 14.9 16.3 14.6 21.5 19.4 10.0 9.3 13.5 13.4 23.3 25.8 12.0 4.5 37.2 10.4 16.2 10.1 19.4 26.3 28.6 25.8 25.4 17.9 25.2 12.1 17.0 21.6 16.4 22.1 24.5 24.9 29.8 24.7 27.0 29.4 22.7 29.0 20.7 4.5 24.2 19.3 44.6 26.9 18.8 4.2 4.0 4.5 4.4 4.0 5.0 4.5 4.1 4.1 4.1 4.9 4.4 10.8 3.2 5.1 0.0 14.3 7.1 13.2 14.1 5.7 6.1 5.3 6.1 3.1 8.6 6.3 3.7 0.0 12.1 17.5 1.8 5.9 11.3 2.3 4.4 10.6 8.4 2.4 8.6 0.0 10.9 17.0 8.6 3.1 3.9 6.3 26.3 9.3 5.9 10.0 10.1 0.0 3.9 6.1 6.6 6.4 1.2 11.5 6.0 5.4 0.0 13.6 9.7 10.3 0.0 0.0 10.5 3.4 10.1 9.5 7.8 3.1 11.6 4.7 4.9 19.7 8.1 10.7 20.3 9.3 6.7 7.4 18.3 10.6 28.1 4.7 11.5 L2HGDH "C14orf160, FLJ12618" ENSG00000087299 "L-2-hydroxyglutarate dehydrogenase" Q9H9P8 14 50237563-50312229 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Excitatory neurons: 60.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065409, HPA069708" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA065409: AB_2685485, HPA069708: AB_2686179" "unprognostic (1.74e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (1.23e-3)" "unprognostic (1.04e-2)" "unprognostic (4.33e-2)" "unprognostic (8.84e-2)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (9.91e-2)" "unprognostic (2.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (9.75e-10)" "unprognostic (1.24e-2)" "unprognostic (5.88e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-2)" 4.6 2.5 2.9 2.2 2.9 2.7 3.7 6.1 5.5 2.3 1.3 4.3 4.7 2.4 3.0 5.1 3.1 2.0 5.2 2.7 2.5 19.6 12.6 1.8 2.6 1.2 2.4 2.5 3.9 6.1 2.3 1.7 1.1 3.3 5.0 11.4 2.8 3.2 15.5 5.1 3.6 2.5 1.2 1.3 4.3 3.9 2.4 3.0 4.8 14.7 3.4 2.4 2.3 4.1 24.3 16.6 6.8 6.6 3.3 2.2 19.1 7.9 4.4 12.2 14.3 26.8 10.8 19.0 9.0 3.2 9.7 17.4 20.6 8.2 13.5 15.2 11.9 41.1 10.9 3.7 3.1 14.7 13.7 2.0 5.2 8.1 7.0 3.1 5.3 19.3 14.7 11.6 3.2 29.0 16.7 6.7 9.9 20.6 17.6 15.6 22.0 14.8 11.4 28.0 13.8 9.9 23.3 17.5 10.4 9.0 22.9 4.0 5.0 7.7 21.5 9.0 10.6 10.5 25.6 26.3 4.3 7.3 8.8 8.6 0.4 0.9 0.9 0.1 2.2 0.8 1.1 1.0 0.6 0.6 1.3 1.7 0.5 1.7 0.1 1.0 1.6 0.5 2.9 2.9 6.1 5.5 2.7 2.5 1.2 2.4 1.1 1.2 2.4 4.1 1.9 41.7 19.2 16.6 5.1 3.7 2.7 2.1 8.6 15.5 3.9 2.2 14.7 2.8 20.4 12.9 56.3 6.4 6.1 4.8 15.6 3.8 35.1 5.2 2.8 4.6 7.8 7.4 60.5 4.2 6.6 5.3 7.7 5.6 18.9 6.0 2.9 14.2 2.1 11.8 61.4 4.3 0.0 2.7 0.6 8.8 2.5 3.3 1.8 13.1 2.4 6.1 7.2 20.6 18.9 2.5 3.6 4.5 3.3 2.7 6.0 21.7 18.4 40.3 0.0 5.8 3.9 14.3 12.6 10.5 6.3 4.9 5.0 4.6 7.6 2.1 L3MBTL4 "FLJ35936, HsT1031" ENSG00000154655 "L3MBTL histone methyl-lysine binding protein 4" Q8NA19 18 5954706-6415237 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 160.4;Late spermatids: 85.8;Microglial cells: 78.7;Oligodendrocyte precursor cells: 191.5;Oligodendrocytes: 252.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 3.4;Karpas-707: 4.8;RPMI-8226: 11.6;SCLC-21H: 5.3;SH-SY5Y: 5.8;U-2 OS: 3.4" "Low region specificity" "Detected in some" "HPA064194, HPA069042" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "HPA064194: AB_2685208, HPA069042: AB_2686071" "unprognostic (1.33e-3)" "unprognostic (8.98e-2)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (3.56e-2)" "unprognostic (1.40e-1)" "unprognostic (1.70e-2)" "unprognostic (1.73e-1)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (1.92e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-2)" "unprognostic (5.08e-2)" "unprognostic (1.00e-1)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" 3.0 4.3 7.1 1.8 11.5 1.6 4.9 0.2 8.4 4.3 0.6 2.1 3.0 3.2 3.6 3.6 4.2 2.5 4.9 3.8 6.8 7.1 8.8 3.9 2.0 3.3 8.2 8.5 6.5 8.5 3.2 0.7 4.7 2.0 2.0 1.7 3.4 2.9 1.0 7.3 3.5 1.3 1.6 2.9 3.2 12.7 6.6 2.9 5.8 1.3 1.6 1.4 4.1 14.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 2.4 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.2 0.0 1.4 3.1 0.0 11.6 0.0 2.0 5.3 5.8 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 3.4 0.1 1.4 0.1 0.0 0.0 1.3 0.0 1.7 0.3 1.1 0.0 0.7 0.3 0.0 0.5 0.1 0.1 0.7 2.5 0.1 0.2 0.1 3.6 0.8 0.1 0.0 0.5 7.1 11.5 0.2 8.4 3.8 6.8 3.3 8.2 4.7 1.6 6.6 14.0 6.5 3.2 12.2 56.2 4.8 7.8 7.0 0.8 10.2 2.2 4.5 4.8 6.4 11.5 4.1 5.5 16.7 0.1 2.7 0.3 3.9 7.4 62.5 8.1 1.2 3.6 11.4 0.8 33.9 5.2 0.0 3.4 1.5 16.9 1.3 15.4 2.5 10.0 3.2 0.0 160.4 1.5 0.0 3.2 5.3 85.8 10.2 2.9 1.8 78.7 27.2 1.8 25.7 191.5 252.9 3.5 1.9 12.8 1.5 10.3 3.5 8.1 1.2 0.6 6.6 6.9 7.2 9.3 2.4 6.5 8.2 0.1 2.1 0.5 2.5 4.6 LAMA1 LAMA ENSG00000101680 "Laminin subunit alpha 1" P25391 18 6941742-7117797 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.9" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Distal enterocytes: 173.6;Granulosa cells: 77.3;Intestinal goblet cells: 44.2;Paneth cells: 35.8;Proximal enterocytes: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 56.0;ASC diff: 41.0;BEWO: 199.6;hTEC/SVTERT24-B: 41.7;SK-MEL-30: 38.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB010179 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010179: AB_2133741" "unprognostic (2.75e-1)" "unprognostic (3.66e-4)" "unprognostic (2.08e-1)" "unprognostic (3.56e-1)" "unprognostic (4.97e-3)" "unprognostic (3.66e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (2.23e-2)" "unprognostic (3.43e-2)" "unprognostic (3.02e-1)" "unprognostic (6.80e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-2)" "unprognostic (4.85e-1)" "unprognostic (3.47e-2)" "unprognostic (7.34e-3)" 0.7 0.0 2.0 0.2 1.5 0.0 1.6 1.9 1.1 0.8 0.5 0.1 0.0 0.9 1.4 0.1 0.2 0.0 0.2 2.0 2.0 2.9 0.1 0.3 0.0 2.0 2.8 1.4 1.1 0.0 1.0 0.1 2.1 0.2 0.0 0.4 1.3 0.6 0.0 0.2 0.0 0.3 2.2 0.1 0.0 5.9 3.0 0.1 2.5 0.0 0.0 0.3 0.2 2.9 0.0 0.0 56.0 0.0 41.0 36.5 199.6 2.0 9.8 9.9 21.5 24.4 0.0 0.0 0.5 3.4 8.0 0.1 0.0 7.3 4.1 0.0 3.2 0.0 11.8 0.0 4.8 0.0 0.0 31.1 1.1 41.7 23.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 2.8 0.0 0.0 38.4 11.6 0.0 0.0 0.0 7.5 20.5 4.2 0.1 0.0 0.0 0.0 3.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 1.9 1.1 2.0 2.0 2.0 2.8 2.1 2.2 3.0 2.9 2.6 6.4 0.0 90.8 0.0 0.0 0.8 0.8 0.6 0.5 2.3 7.2 1.9 4.3 0.0 0.0 0.0 4.1 0.0 173.6 0.0 0.0 1.6 4.1 0.6 0.2 1.2 0.0 1.4 0.5 3.1 4.2 0.0 4.3 0.0 77.3 0.0 0.1 0.9 0.0 1.7 44.2 0.0 0.0 0.0 3.7 0.0 0.2 0.0 15.0 0.0 3.4 0.0 4.0 1.8 0.0 35.8 0.0 0.0 1.0 47.5 1.4 0.1 0.3 0.0 0.6 3.4 0.4 2.5 0.3 0.0 4.8 0.2 4.6 16.5 0.3 LARS2 "KIAA0028, LEURS, MGC26121, mtLeuRS" ENSG00000011376 "Leucyl-tRNA synthetase 2, mitochondrial" Q15031 3 45388561-45554726 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Excitatory neurons: 35.4;Inhibitory neurons: 37.8;Oligodendrocyte precursor cells: 22.6;Oligodendrocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035951, HPA045450, HPA066085" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Nucleoplasm "HPA035951: AB_10672997, HPA045450: AB_2679328, HPA066085: AB_2685612" "unprognostic (3.89e-1)" "unprognostic (3.89e-1)" "prognostic favorable (1.71e-4)" "unprognostic (3.02e-2)" "unprognostic (3.77e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-3)" "unprognostic (9.19e-2)" "unprognostic (6.13e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-1)" "unprognostic (4.37e-2)" "prognostic favorable (1.32e-11)" "unprognostic (2.81e-1)" "unprognostic (5.74e-2)" "unprognostic (9.90e-2)" "unprognostic (9.07e-2)" 3.3 4.7 9.5 3.4 10.3 2.4 3.9 10.1 11.7 3.7 9.2 6.9 3.9 4.6 4.3 4.2 4.5 3.0 5.5 9.3 10.5 7.5 8.1 2.9 4.3 9.5 10.2 3.8 2.4 12.3 3.7 4.2 9.5 4.3 6.9 4.2 3.6 4.2 6.2 3.6 2.9 4.4 9.2 3.2 3.6 2.2 11.5 6.9 4.5 6.4 4.8 5.0 3.7 8.5 6.3 11.2 10.7 9.3 11.8 13.0 11.1 11.6 15.7 24.7 16.2 20.3 8.8 13.8 8.9 18.0 18.2 5.8 49.0 30.4 16.0 9.5 12.7 12.9 13.6 18.4 12.1 20.9 4.4 19.0 16.8 26.0 12.5 13.1 14.9 19.5 25.1 5.5 19.0 9.7 21.1 11.6 28.4 15.0 21.9 8.9 9.8 16.9 23.6 18.8 7.6 9.7 17.3 7.9 11.8 13.5 14.6 14.7 9.1 12.1 8.3 8.5 12.3 5.3 12.3 15.4 14.0 16.9 9.5 0.0 0.6 0.6 1.2 0.9 1.5 1.0 0.7 1.1 1.2 0.5 0.8 1.0 0.3 1.9 0.8 1.0 0.6 0.7 9.5 10.3 10.1 11.7 9.3 10.5 9.5 10.2 9.5 9.2 11.5 8.5 3.9 0.0 2.0 28.7 4.8 1.1 1.5 1.8 3.4 5.5 3.2 2.8 9.0 1.5 1.8 5.5 4.2 5.0 3.5 4.4 5.9 2.9 0.6 7.6 5.7 4.2 4.8 5.2 35.4 2.7 5.2 3.2 6.6 4.9 1.3 9.8 2.2 7.7 5.4 1.7 37.8 4.5 0.0 2.9 1.3 1.2 1.2 2.6 1.8 19.7 2.3 4.0 2.1 22.6 25.2 3.2 7.0 2.2 5.0 1.9 2.6 2.4 2.9 4.7 0.0 3.1 2.9 0.7 2.4 4.8 1.3 2.9 3.2 8.3 6.8 1.7 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 438.4;granulocytes: 309.1;Hofbauer cells: 264.4;Kupffer cells: 401.2;Langerhans cells: 337.6;Late spermatids: 290.9;Macrophages: 466.1;monocytes: 535.7;NK-cells: 471.7;T-cells: 375.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 875.8;HDLM-2: 799.3;HL-60: 850.7;HMC-1: 861.7;JURKAT: 792.7;NB-4: 789.2;THP-1: 840.5;U-698: 1105.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 85.9 31.1 11.3 396.9 13.1 709.0 43.9 13.9 30.9 28.5 16.8 54.7 42.4 27.4 402.7 29.5 21.5 76.4 14.5 11.3 14.2 13.1 89.0 173.8 563.5 19.7 18.9 10.0 12.2 12.6 4.3 67.2 21.3 184.5 71.2 4.9 44.4 24.3 7.1 40.6 62.3 60.4 18.6 375.2 53.2 33.2 24.8 499.8 23.6 17.8 605.1 133.0 7.7 29.9 36.1 0.2 1.9 0.0 0.0 0.0 409.8 0.1 1.2 3.9 2.9 237.4 1.4 875.8 179.5 0.0 249.1 1.7 0.1 0.6 3.9 799.3 202.9 187.6 0.4 1.1 0.9 850.7 861.7 2.3 0.1 1.4 1.2 0.3 0.0 792.7 100.4 569.7 0.0 2.8 624.8 789.2 1.0 0.4 8.2 451.6 1.6 638.2 0.0 233.8 2.8 7.5 1.9 91.8 6.4 25.0 6.4 840.5 3.1 22.0 13.6 1.5 25.5 135.3 292.5 1105.7 17.0 530.9 3.6 1007.3 1559.5 810.8 915.7 1806.2 822.0 342.3 539.6 761.2 1134.5 251.6 330.2 560.5 1908.6 650.6 1826.1 297.5 598.1 3644.2 11.3 13.1 13.9 30.9 11.3 14.2 19.7 18.9 21.3 18.6 24.8 29.9 7.4 32.1 73.2 0.3 185.2 12.0 1.2 0.0 1.8 0.4 10.3 11.7 4.2 5.7 18.0 3.7 0.0 9.8 438.4 0.2 0.0 16.9 113.1 4.7 42.8 9.6 1.2 63.9 0.5 16.3 68.3 10.9 19.9 7.0 309.1 0.7 12.5 24.0 264.4 0.0 0.5 0.5 0.0 401.2 337.6 290.9 1.2 466.1 23.2 17.8 535.7 23.7 471.7 0.5 1.5 6.8 2.4 1.9 102.4 42.0 0.1 1.5 13.8 1.2 0.0 3.1 6.2 2.7 1.6 2.2 11.8 13.5 375.3 0.5 0.4 4.0 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LEF1 "TCF10, TCF1ALPHA, TCF7L3" ENSG00000138795 "Lymphoid enhancer binding factor 1" Q9UJU2 4 108047545-108168956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lymphoid tissue: 349.2" "Cell type enhanced" "Detected in many" "Melanocytes: 33.8;Microglial cells: 145.2;T-cells: 70.3" "Cancer enhanced" "Detected in all" "melanoma: 25.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 142.6" "Lineage enriched" "Detected in many" 4 "T-cells: 142.6" "Group enriched" "Detected in many" 5 "JURKAT: 579.6;MOLT-4: 569.0;REH: 454.8" "Region enhanced" "Detected in all" "thalamus: 22.6" "Low region specificity" "Detected in all" "HPA002087, CAB019405" Enhanced Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "CAB019405: AB_823558, HPA002087: AB_1079245" "unprognostic (1.03e-3)" "unprognostic (7.36e-3)" "unprognostic (2.97e-2)" "prognostic favorable (1.37e-5)" "unprognostic (9.08e-2)" "unprognostic (5.24e-2)" "unprognostic (3.81e-2)" "unprognostic (1.10e-2)" "unprognostic (1.77e-1)" "unprognostic (5.21e-2)" "unprognostic (9.99e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.47e-6)" "unprognostic (1.12e-1)" "unprognostic (5.22e-2)" "unprognostic (7.88e-2)" "unprognostic (8.91e-2)" 1.0 12.7 10.7 13.8 7.6 11.6 2.0 6.1 7.9 4.2 14.3 1.5 0.7 8.0 4.8 3.2 5.1 3.9 0.2 5.7 9.9 2.5 0.3 3.3 31.3 8.9 11.2 1.1 0.1 0.3 1.0 11.0 9.4 3.7 1.4 0.5 1.0 1.0 0.1 2.8 4.1 3.9 5.9 9.8 1.5 12.3 18.2 349.2 3.0 0.1 22.8 5.5 3.0 5.5 0.1 0.0 8.0 0.0 0.0 0.0 0.0 0.2 7.2 1.8 4.7 27.1 0.0 0.0 0.1 0.0 2.5 0.2 7.9 0.0 3.7 0.3 17.6 6.9 0.0 0.0 0.0 23.6 2.9 0.4 0.4 0.0 0.7 3.5 0.0 579.6 14.2 0.0 2.6 1.0 569.0 0.0 1.7 6.3 1.4 454.8 9.1 0.2 2.4 1.3 3.0 5.2 0.0 0.5 83.8 6.7 2.4 0.2 0.0 11.9 10.3 0.0 15.3 38.3 17.0 100.9 7.8 0.0 48.4 0.3 0.2 0.0 8.2 0.0 1.6 0.6 68.3 29.9 0.1 0.9 142.6 102.2 1.9 32.9 0.3 0.5 97.7 36.8 10.7 7.6 6.1 7.9 5.7 9.9 8.9 11.2 9.4 5.9 18.2 5.5 1.4 3.2 1.9 2.0 4.4 3.3 1.4 1.0 24.5 0.1 0.4 5.0 1.6 0.0 0.7 0.0 0.0 0.1 6.2 0.0 13.7 0.0 4.2 5.8 22.3 22.0 0.0 9.2 0.2 0.0 0.2 2.1 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.2 4.1 0.3 1.4 7.9 0.6 2.0 33.8 145.2 3.5 0.6 10.3 0.5 0.6 0.1 0.0 0.0 5.4 1.8 0.0 0.5 2.3 0.3 0.0 0.6 9.0 16.1 6.6 11.3 1.3 0.4 70.3 0.0 0.9 0.4 LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241278-128257629 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "adipose tissue: 307.5;breast: 90.1" "Group enriched" "Detected in some" 44 "Extravillous trophoblasts: 124.2;Syncytiotrophoblasts: 432.2" "Cancer enhanced" "Detected in some" "breast cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.1;SuSa: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" CAB010490 Approved "Secreted to blood" NA NA 17000000 19000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB010490: AB_2296951" "unprognostic (8.19e-3)" "unprognostic (5.33e-1)" "unprognostic (1.60e-4)" "unprognostic (1.19e-1)" "unprognostic (7.99e-3)" "unprognostic (1.83e-1)" "unprognostic (6.56e-3)" "unprognostic (1.98e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.23e-2)" "unprognostic (6.84e-2)" 307.5 0.8 0.1 5.0 0.1 0.1 90.1 0.5 0.3 0.1 0.1 2.0 0.1 0.0 0.0 0.2 0.1 1.2 1.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 2.4 0.0 0.0 4.6 0.1 0.0 0.4 0.0 1.1 0.0 0.7 3.9 1.2 0.1 0.0 0.2 0.5 0.2 0.1 0.3 0.2 1.2 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.8 0.1 0.6 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 124.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.1 432.2 0.1 0.1 0.0 0.1 LFNG SCDO3 ENSG00000106003 "LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q8NES3 7 2512529-2529177 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 74.4" "Cell type enhanced" "Detected in many" "dendritic cells: 40.3;Enteroendocrine cells: 87.4;monocytes: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 37.7;OE19: 46.4;RH-30: 46.0;U-2 OS: 49.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069130 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" NA NA 880000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "Nuclear membrane" "HPA069130: AB_2686091" "unprognostic (4.58e-2)" "unprognostic (1.17e-2)" "unprognostic (2.52e-2)" "prognostic favorable (6.36e-4)" "unprognostic (1.85e-2)" "unprognostic (8.34e-2)" "unprognostic (4.15e-1)" "unprognostic (7.86e-2)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.89e-1)" "unprognostic (5.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.09e-1)" "unprognostic (1.97e-2)" "unprognostic (2.28e-2)" 16.7 6.5 23.3 17.3 25.9 9.8 13.7 29.3 22.4 9.9 11.1 23.1 15.5 9.4 2.2 11.4 6.1 11.8 13.1 17.4 30.1 9.0 2.5 14.4 18.6 34.1 35.6 1.8 74.4 3.0 3.7 6.5 24.8 17.1 12.0 3.0 33.4 4.6 4.6 58.2 17.2 5.8 25.0 20.9 37.8 4.2 38.1 5.8 6.7 3.6 10.8 12.2 13.8 23.6 1.5 14.3 18.4 2.5 2.0 1.7 1.2 5.4 2.8 4.7 5.9 6.0 37.7 1.1 16.7 14.8 8.1 27.1 2.9 5.1 2.3 8.6 0.6 4.3 7.7 3.2 0.1 6.2 7.7 3.3 12.6 7.8 0.8 3.2 1.9 0.3 0.7 0.2 3.6 34.5 0.1 8.7 22.4 46.4 10.3 1.8 46.0 2.9 1.8 4.5 16.9 4.2 6.2 1.4 0.3 4.7 10.2 7.3 4.5 10.5 49.7 0.4 15.4 0.2 0.0 1.4 11.8 16.4 2.0 6.3 5.3 12.7 1.8 6.9 2.0 1.1 1.7 0.9 2.3 2.0 1.8 1.8 2.8 1.3 6.6 0.6 4.2 1.7 23.3 25.9 29.3 22.4 17.4 30.1 34.1 35.6 24.8 25.0 38.1 23.6 23.3 6.4 6.0 18.9 15.6 6.8 2.5 10.6 3.4 8.5 5.3 12.4 3.6 5.7 2.8 0.0 0.0 0.1 40.3 23.1 0.0 1.2 0.1 2.4 8.5 16.0 87.4 2.7 0.0 6.4 0.3 5.7 30.5 1.2 17.7 0.1 13.9 0.6 7.0 0.0 0.1 34.5 6.1 30.4 13.8 0.5 1.8 30.6 3.6 11.2 38.2 31.3 19.6 1.5 0.1 21.7 3.1 0.0 12.6 2.2 8.8 0.4 1.2 0.8 0.0 0.6 5.0 0.3 3.1 0.6 4.0 0.0 15.9 0.5 15.3 0.7 LGI4 ENSG00000153902 "Leucine rich repeat LGI family member 4" Q8N135 19 35124513-35142451 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.7;Distal enterocytes: 33.1;Muller glia cells: 95.5;Sertoli cells: 78.9;Smooth muscle cells: 104.4" "Group enriched" "Detected in many" 6 "glioma: 4.5;melanoma: 11.5;renal cancer: 13.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 27 "WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042116, HPA043556" Approved Approved "Golgi apparatus" "Secreted in brain" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA042116: AB_2677855, HPA043556: AB_2678550" "unprognostic (3.79e-1)" "unprognostic (6.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-2)" "unprognostic (3.71e-2)" "unprognostic (2.12e-2)" "unprognostic (4.26e-2)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.84e-7)" "unprognostic (1.71e-2)" "unprognostic (4.47e-1)" "unprognostic (7.73e-2)" "unprognostic (7.13e-2)" 77.6 5.4 71.2 4.1 72.3 0.2 36.1 70.3 98.4 99.9 52.1 100.5 3.6 35.5 2.3 15.0 43.7 5.0 39.4 67.8 61.3 4.7 8.0 14.3 2.1 86.5 68.4 13.3 6.4 1.4 4.4 3.6 70.1 37.2 3.7 7.2 12.2 13.3 39.1 21.2 35.1 4.8 72.8 1.9 27.0 2.7 72.0 0.5 19.1 5.4 0.5 33.5 79.3 81.4 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 71.2 72.3 70.3 98.4 67.8 61.3 86.5 68.4 70.1 72.8 72.0 81.4 13.3 0.0 0.0 74.7 0.2 2.5 0.6 0.3 3.4 0.8 1.5 1.5 17.1 0.0 0.8 1.8 2.1 0.0 0.2 33.1 0.0 0.0 0.1 0.2 2.8 5.4 1.8 0.0 21.9 0.0 0.3 12.7 0.0 0.2 0.0 0.0 7.9 2.0 0.1 0.0 2.2 0.9 0.0 0.0 4.6 0.3 14.6 0.7 10.6 5.6 0.1 95.5 0.0 2.0 9.2 0.1 21.8 7.2 0.3 1.2 1.1 0.1 0.9 3.1 78.9 7.9 104.4 2.8 2.8 0.8 2.4 0.0 0.7 0.0 0.7 1.1 LGR4 GPR48 ENSG00000205213 "Leucine rich repeat containing G protein-coupled receptor 4" Q9BXB1 11 27365961-27472790 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, Immunity, Innate immunity, Spermatogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 204.4;Distal enterocytes: 123.3;Glandular and luminal cells: 137.7;Syncytiotrophoblasts: 128.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 83.5;RPTEC TERT1: 100.4;U-2197: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030267, HPA054350" Uncertain Approved "Centriolar satellite" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" "HPA030267: AB_10610004, HPA054350: " "unprognostic (5.27e-3)" "unprognostic (5.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.59e-1)" "unprognostic (4.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "unprognostic (2.00e-2)" "unprognostic (4.63e-2)" "unprognostic (5.84e-3)" "unprognostic (2.10e-1)" "prognostic favorable (2.00e-7)" "unprognostic (5.01e-1)" "unprognostic (3.59e-1)" "unprognostic (3.54e-2)" "unprognostic (1.76e-1)" 16.4 16.8 10.2 8.1 10.2 2.4 16.1 13.0 9.2 7.5 10.2 36.8 22.6 10.2 13.3 13.7 10.2 9.0 19.4 7.8 10.5 51.5 55.7 3.2 1.5 14.1 10.4 22.9 59.7 6.4 6.8 34.4 12.8 15.4 36.8 44.4 18.1 16.1 14.4 18.3 24.7 13.2 13.4 11.7 31.0 13.9 10.1 4.4 15.2 8.2 3.0 10.1 11.7 18.0 28.3 50.7 49.5 5.7 4.5 3.1 56.0 15.7 14.8 13.8 11.8 7.6 0.5 0.1 10.1 21.2 23.2 45.8 83.5 31.1 23.5 0.2 37.0 15.3 28.4 36.1 1.4 1.6 0.1 4.1 19.5 9.5 21.0 57.0 7.0 0.0 4.5 0.1 5.7 9.0 0.1 2.7 47.9 76.3 20.4 0.2 33.8 3.3 100.4 12.1 0.7 6.0 7.7 45.7 4.6 37.6 15.1 23.4 22.6 10.2 8.2 82.6 14.6 18.9 15.2 0.0 17.3 0.0 6.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 10.2 13.0 9.2 7.8 10.5 14.1 10.4 12.8 13.4 10.1 18.0 1.7 3.2 0.5 204.4 1.4 30.3 13.5 33.1 38.7 18.6 17.2 14.1 26.6 24.3 15.4 44.1 25.0 55.1 0.4 123.3 3.9 21.4 7.1 75.4 11.5 3.9 16.8 3.4 35.6 50.7 29.2 14.5 43.3 137.7 0.0 78.6 3.6 60.7 8.1 25.2 51.6 47.1 20.3 5.3 5.7 2.2 5.0 1.6 7.2 15.0 2.1 109.8 0.0 36.7 62.1 31.4 48.8 17.0 0.6 11.7 37.9 19.4 14.5 14.8 6.6 6.9 13.0 1.3 1.4 36.8 21.9 128.6 1.8 6.3 55.5 19.7 LHPP HDHD2B ENSG00000107902 "Phospholysine phosphohistidine inorganic pyrophosphate phosphatase" Q9H008 10 124461823-124617888 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 198.8;choroid plexus: 104.0" "Cell type enhanced" "Detected in many" "Early spermatids: 114.9;Late spermatids: 163.3;Proximal tubular cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009163, HPA009269" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 820000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Cytosol" "HPA009163: AB_1079250, HPA009269: AB_1079249" "unprognostic (3.46e-2)" "unprognostic (1.23e-2)" "unprognostic (4.78e-2)" "unprognostic (3.89e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-1)" "unprognostic (5.77e-3)" "unprognostic (2.02e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (6.42e-2)" "unprognostic (5.55e-2)" "unprognostic (1.79e-3)" "unprognostic (2.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" 12.9 32.0 135.1 8.2 173.7 10.5 13.0 159.3 190.6 18.5 104.0 27.1 23.4 20.2 13.4 24.1 10.0 10.2 17.5 129.7 156.5 28.4 60.2 9.2 11.8 179.2 165.8 9.0 15.9 9.2 14.5 8.6 170.7 14.0 8.5 7.5 18.3 12.5 10.2 15.3 21.1 10.2 151.1 14.0 20.1 24.2 156.3 9.7 29.4 4.8 15.2 14.7 16.1 198.8 24.7 12.0 4.7 12.1 18.2 14.7 12.8 8.2 18.0 5.5 10.0 2.1 22.4 24.4 19.7 13.5 6.1 26.1 1.4 4.7 5.7 5.4 16.3 17.6 4.1 11.4 18.5 3.6 27.6 11.0 20.0 5.4 13.0 16.0 8.8 21.4 8.9 9.5 6.9 24.5 12.0 11.3 8.5 10.4 6.8 12.4 5.3 31.8 12.1 3.2 2.7 14.2 6.3 22.6 8.2 6.5 17.2 0.6 4.2 8.5 12.2 7.2 2.3 7.9 2.5 7.8 7.7 6.8 2.0 8.1 28.8 25.3 16.1 24.5 20.8 41.0 18.7 17.2 35.6 43.3 22.4 16.0 4.8 7.9 29.0 13.4 32.1 24.4 135.1 173.7 159.3 190.6 129.7 156.5 179.2 165.8 170.7 151.1 156.3 198.8 5.0 3.2 14.8 22.9 29.1 7.4 9.4 22.1 13.1 6.0 19.8 19.8 15.8 12.8 19.4 7.3 0.0 54.2 6.2 17.9 33.2 5.3 114.9 17.7 12.7 4.6 9.5 19.8 29.4 2.3 24.7 11.2 19.9 8.2 10.8 23.3 6.1 61.1 26.5 11.8 27.8 21.3 24.4 16.0 8.1 163.3 5.9 12.9 17.8 8.4 15.6 9.8 8.2 15.6 76.4 3.3 30.2 10.5 19.7 6.7 80.5 93.8 24.9 6.4 13.1 5.2 9.5 33.1 11.3 30.7 5.4 24.2 12.1 12.4 23.0 16.3 LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.0;lymphoid tissue: 49.9" "Group enriched" "Detected in many" 5 "Hofbauer cells: 63.4;Kupffer cells: 88.6;Macrophages: 88.8;monocytes: 71.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.8" "Group enriched" "Detected in many" 4 "granulocytes: 44.8;monocytes: 15.4" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" 9.9 3.4 0.4 8.3 0.4 14.6 2.9 0.4 2.1 1.2 0.9 2.7 0.3 1.2 0.3 1.3 5.4 0.1 3.4 0.4 0.4 2.3 4.1 27.0 0.3 1.2 0.8 1.0 1.9 0.0 1.3 1.2 1.3 1.7 0.0 0.2 2.4 0.0 1.1 0.8 2.6 0.1 0.6 49.9 2.3 0.5 1.8 0.6 1.6 0.0 0.2 3.2 1.6 1.4 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.4 0.6 0.1 14.3 0.2 0.1 0.3 0.0 7.2 0.1 0.0 0.1 44.8 0.0 5.6 0.5 0.0 11.6 0.4 0.4 0.4 2.1 0.4 0.4 1.2 0.8 1.3 0.6 1.8 1.4 1.5 9.6 13.0 0.3 2.2 2.4 1.2 6.5 0.0 0.7 1.6 2.2 0.4 4.3 8.3 1.8 0.0 1.5 2.1 0.6 0.0 0.3 1.3 0.8 1.9 3.0 0.0 0.8 0.2 0.6 6.7 2.9 0.0 2.2 7.6 0.5 1.8 3.2 63.4 0.0 0.1 1.9 0.0 88.6 8.4 4.1 0.3 88.8 1.8 1.9 71.2 0.9 3.1 0.0 0.1 0.2 1.3 0.7 2.1 1.6 0.4 0.4 5.2 2.9 6.6 4.3 1.3 0.8 1.5 0.1 3.0 1.2 3.8 2.6 2.0 0.4 LIN7A "LIN-7A, MALS-1, TIP-33, VELI1" ENSG00000111052 "Lin-7 homolog A, crumbs cell polarity complex component" O14910 12 80792520-80937934 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.9;retina: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 77.3;Early spermatids: 107.2;Excitatory neurons: 135.5;Inhibitory neurons: 93.1;Late spermatids: 76.9;Spermatocytes: 61.3" "Cancer enhanced" "Detected in many" "renal cancer: 8.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 18.8;eosinophil: 15.8;neutrophil: 29.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 29.8" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;ASC TERT1: 31.4;HAP1: 25.2;HDLM-2: 29.6;HL-60: 29.1;NB-4: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071562 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071562: AB_2732181" "unprognostic (7.11e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-3)" "unprognostic (3.04e-2)" "unprognostic (8.24e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-2)" "unprognostic (8.83e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "prognostic favorable (1.63e-11)" "unprognostic (5.01e-5)" "unprognostic (7.79e-2)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" 5.0 3.1 5.5 2.4 6.5 27.9 5.4 22.2 8.0 7.9 1.0 1.9 0.5 8.5 0.5 0.9 3.7 4.0 6.3 6.4 6.0 8.7 17.7 5.1 2.6 1.9 6.9 3.7 0.5 0.9 6.0 5.3 3.1 1.8 0.6 26.6 0.8 0.7 1.0 0.7 2.1 4.6 2.3 4.6 1.1 7.1 6.9 0.7 4.2 2.5 1.2 3.9 4.6 3.6 0.0 0.6 5.0 0.0 21.3 31.4 0.0 12.8 5.9 5.1 1.1 9.9 0.0 0.0 0.0 4.9 0.1 0.0 25.2 0.0 1.5 29.6 7.8 0.0 0.2 15.6 2.6 29.1 0.2 7.8 0.0 0.5 0.5 1.2 4.1 0.0 0.0 0.0 2.3 0.3 0.0 27.0 4.7 0.3 0.1 0.0 18.7 0.0 2.9 4.1 10.2 0.0 0.0 0.0 0.1 0.3 1.1 15.5 0.0 4.0 1.5 2.1 0.1 4.4 0.0 0.0 0.4 0.0 0.2 18.8 5.2 15.8 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 29.8 0.0 0.2 0.0 0.1 1.2 5.5 6.5 22.2 8.0 6.4 6.0 1.9 6.9 3.1 2.3 6.9 3.6 4.8 22.4 5.8 18.6 0.0 0.8 4.8 0.0 0.0 77.3 10.8 3.4 22.8 8.6 0.6 25.8 2.1 0.4 0.2 0.3 9.8 1.3 107.2 1.9 8.9 1.9 1.8 0.4 135.5 0.2 0.1 4.9 0.0 3.5 0.0 0.1 1.8 21.5 2.5 30.3 93.1 0.5 0.0 5.2 0.7 76.9 4.7 4.2 0.0 9.4 6.5 42.6 0.0 23.1 2.7 0.0 1.2 1.5 0.4 2.0 20.1 26.5 0.7 11.2 13.1 5.0 19.2 61.3 1.3 0.0 0.4 0.7 0.6 3.5 1.1 1.8 LINS1 "LINS, MRT27, WINS1" ENSG00000140471 "Lines homolog 1" Q8NG48 15 100559369-100603230 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038578, HPA038579" Approved Approved Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA038578: AB_2676095, HPA038579: AB_10697393" "unprognostic (9.87e-2)" "unprognostic (3.32e-3)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (7.37e-2)" "unprognostic (6.16e-2)" "unprognostic (7.14e-2)" "unprognostic (1.06e-1)" "unprognostic (2.48e-2)" "unprognostic (3.36e-2)" "unprognostic (1.65e-1)" "unprognostic (1.71e-3)" "unprognostic (1.14e-2)" "unprognostic (2.93e-1)" "unprognostic (2.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.28e-2)" 4.2 4.1 2.5 8.3 2.2 5.7 7.7 3.1 3.3 7.2 2.8 5.8 4.1 6.6 9.4 7.0 5.4 4.4 3.1 2.4 1.7 6.0 5.5 6.2 11.5 1.6 1.4 6.4 5.4 6.1 3.5 6.4 1.8 6.1 7.0 6.6 5.1 4.6 4.3 6.9 4.5 6.2 1.1 8.4 6.3 7.6 2.3 9.1 8.4 5.1 10.0 5.8 4.9 2.8 4.4 6.6 8.2 8.2 5.9 8.0 7.5 6.8 7.6 7.6 8.1 6.2 8.4 11.6 3.9 6.2 5.7 18.5 7.8 8.6 7.9 4.0 11.1 10.4 10.7 4.9 4.9 8.9 6.3 7.7 7.4 5.9 9.4 7.6 9.0 6.4 17.3 9.1 4.7 5.7 5.3 7.6 9.6 16.7 8.1 7.8 13.1 10.8 6.6 11.8 4.2 5.5 6.3 6.1 10.2 10.4 10.3 6.7 6.5 9.5 8.5 6.8 8.9 9.7 13.4 10.5 6.1 11.4 7.7 12.4 7.9 11.7 16.3 7.5 23.9 12.7 25.7 18.1 8.4 11.9 35.0 25.1 10.4 15.0 6.7 6.8 17.6 10.5 2.5 2.2 3.1 3.3 2.4 1.7 1.6 1.4 1.8 1.1 2.3 2.8 7.7 19.2 5.9 0.0 16.6 0.0 9.7 0.0 11.4 16.1 11.3 8.3 0.0 5.7 2.5 12.9 18.8 8.8 20.4 4.9 5.9 5.9 10.8 6.6 11.4 5.7 4.9 11.6 0.0 5.1 5.5 7.2 15.3 6.3 1.3 10.3 7.1 7.6 15.3 16.8 0.0 5.8 0.0 6.0 0.0 1.7 12.2 6.9 0.0 0.0 7.9 9.3 26.8 0.0 0.0 5.4 3.2 7.2 12.5 9.0 10.5 4.7 7.3 16.0 13.1 8.5 5.8 20.7 12.9 9.9 0.0 12.4 29.8 18.9 4.8 7.5 LIPK "bA186O14.2, LIPL2" ENSG00000204021 "Lipase family member K" Q5VXJ0 10 88724544-88752756 "Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 32.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SK-BR-3: 2.6" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 8: SK-BR-3 - Unknown function" "unprognostic (7.65e-2)" "unprognostic (8.64e-2)" "unprognostic (3.57e-2)" "unprognostic (3.19e-7)" "unprognostic (1.25e-1)" "unprognostic (1.60e-2)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 27.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 67.1;Club cells: 38.4;Early spermatids: 41.9;Endometrial stromal cells: 34.0;Extravillous trophoblasts: 44.2;Fibroblasts: 79.1;Peritubular cells: 39.1;Smooth muscle cells: 32.7" "Cancer enhanced" "Detected in all" "renal cancer: 39.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 777.3;fHDF/TERT166: 1790.7;HSkMC: 356.3;U-138 MG: 475.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043930 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 550000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043930: AB_2678736" "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavorable (3.32e-4)" 27.9 2.4 0.4 6.8 0.4 0.2 17.6 0.5 0.9 10.8 0.8 4.2 3.8 6.2 1.7 5.6 8.9 18.8 23.9 0.3 0.4 4.5 2.1 13.6 3.3 1.3 1.4 5.4 3.3 0.9 1.2 8.1 0.8 4.1 4.5 1.1 3.2 2.6 1.9 12.4 3.7 10.0 1.2 2.6 4.4 1.4 0.5 0.9 6.9 2.1 1.4 14.1 4.8 1.0 0.8 0.2 2.0 0.9 168.7 185.2 0.1 777.3 205.3 73.2 246.4 0.5 0.3 0.1 16.5 1790.7 3.7 0.2 4.5 3.5 196.4 0.1 2.0 0.0 16.3 9.3 203.4 0.4 0.1 356.3 4.4 137.6 7.4 329.3 95.3 0.1 0.0 0.1 83.6 0.0 0.1 0.3 6.4 0.1 1.9 0.1 7.4 0.9 4.9 0.5 0.5 4.2 72.1 0.1 12.9 29.8 0.6 0.6 6.8 475.5 23.2 272.8 9.3 0.0 0.1 0.2 207.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.3 0.4 1.3 1.4 0.8 1.2 0.5 1.0 20.0 9.6 1.1 0.0 0.2 7.8 1.9 67.1 0.0 0.6 1.3 1.1 2.1 0.0 38.4 0.0 0.0 0.8 0.1 0.0 0.0 7.2 41.9 8.4 34.0 9.4 0.0 0.0 0.3 0.6 44.2 79.1 0.0 6.6 0.0 0.1 10.8 0.5 2.2 1.7 2.0 0.0 2.0 0.8 21.6 5.0 14.0 1.3 5.4 1.9 0.6 0.0 0.0 0.0 0.0 1.3 0.0 39.1 0.3 2.8 0.0 0.1 8.3 1.7 19.7 1.1 32.7 0.8 0.6 1.8 10.7 4.8 1.1 0.4 0.1 0.9 LPAR5 "GPR92, GPR93, KPG_010, LPA5" ENSG00000184574 "Lysophosphatidic acid receptor 5" Q9H1C0 12 6618835-6635960 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.9" "Cell type enhanced" "Detected in many" "B-cells: 26.5;Hofbauer cells: 38.0;Microglial cells: 33.7;Proximal enterocytes: 18.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 18.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 83.8;T-cells: 66.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 10.5;HEL: 19.6;HMC-1: 26.0;K-562: 14.8;OE19: 9.4;U-698: 13.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA013170 Approved NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "HPA013170: AB_1849314" "unprognostic (1.94e-1)" "unprognostic (6.43e-2)" "unprognostic (1.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (1.37e-1)" "unprognostic (5.95e-2)" "unprognostic (3.45e-1)" "unprognostic (1.41e-2)" "unprognostic (3.62e-3)" "unprognostic (2.07e-1)" "unprognostic (6.27e-2)" "unprognostic (7.99e-3)" "unprognostic (5.43e-1)" "prognostic favorable (6.56e-5)" "unprognostic (7.43e-2)" 1.9 2.5 6.0 5.3 6.1 1.0 1.3 6.1 5.9 5.8 3.4 8.9 9.7 0.5 2.7 20.9 1.6 1.7 4.1 5.4 6.8 0.7 1.3 1.9 8.9 10.3 8.9 0.7 0.5 0.8 1.0 5.4 9.4 1.0 8.3 0.2 5.5 1.3 0.2 6.9 8.9 1.0 10.2 9.3 7.2 1.6 11.8 2.6 1.6 0.1 12.4 2.1 9.6 14.4 5.8 0.7 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.3 10.5 4.3 1.3 0.0 0.1 7.0 0.0 3.2 0.0 0.0 0.0 19.6 0.6 0.4 0.0 0.0 26.0 0.0 3.5 0.1 1.5 0.0 0.0 4.0 14.8 0.0 0.0 0.5 0.6 6.1 0.1 9.4 1.0 4.8 0.0 0.0 0.0 3.3 0.1 0.1 3.0 0.0 0.0 1.1 0.0 2.2 0.1 0.0 3.9 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 10.4 0.3 0.1 66.8 3.4 51.2 83.8 11.2 40.2 17.3 82.7 10.8 24.6 0.8 4.6 6.1 1.1 18.0 20.1 6.0 6.1 6.1 5.9 5.4 6.8 10.3 8.9 9.4 10.2 11.8 14.4 0.2 0.0 0.0 0.0 26.5 1.5 0.4 3.9 1.8 0.0 0.6 0.5 2.8 1.5 4.4 1.8 0.0 0.3 2.8 16.9 0.0 0.3 4.9 0.4 0.1 1.5 1.2 0.8 0.2 0.9 0.2 0.6 3.6 0.7 16.5 0.0 1.1 0.2 38.0 0.0 0.3 11.1 2.0 15.6 7.0 14.5 0.0 13.9 0.0 33.7 4.6 0.1 17.5 0.5 0.1 9.4 16.8 0.0 2.7 0.7 18.4 0.1 0.6 0.1 0.0 0.1 0.2 0.6 1.4 10.3 1.3 0.5 6.9 0.0 13.0 2.2 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 LPP ENSG00000145012 "LIM domain containing preferred translocation partner in lipoma" Q93052 3 188153284-188890671 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 566.5;Late spermatids: 1737.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 97.0;EFO-21: 115.2;U-698: 200.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011133, HPA017342" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 2700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Focal adhesion sites, Cytosol" "HPA011133: AB_1853247, HPA017342: AB_1853249" "unprognostic (1.50e-1)" "unprognostic (4.97e-3)" "unprognostic (1.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.86e-1)" "unprognostic (4.05e-1)" "unprognostic (2.43e-3)" "unprognostic (7.97e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (3.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.57e-3)" "unprognostic (2.25e-2)" "unprognostic (6.86e-2)" "unprognostic (2.82e-3)" "unprognostic (1.48e-1)" 29.3 10.8 6.7 28.4 8.9 9.9 18.8 9.1 9.7 27.5 27.3 73.3 13.8 61.9 11.8 49.4 32.2 21.3 16.7 6.1 11.2 11.5 12.1 19.1 17.2 15.6 7.9 14.7 8.8 9.9 2.9 11.5 12.6 39.0 31.7 2.4 12.0 53.1 12.4 12.0 23.0 81.3 6.6 10.8 32.7 18.6 13.8 8.0 8.8 9.1 21.4 57.0 22.1 7.8 25.6 23.3 16.7 11.3 35.3 36.0 17.9 16.0 20.9 11.8 7.8 42.2 12.1 97.0 115.2 37.3 14.7 10.7 5.2 11.0 29.5 10.7 5.7 4.6 18.4 11.1 15.0 2.0 5.5 25.7 15.3 26.4 22.5 16.9 20.1 5.2 0.2 2.0 21.0 8.1 5.1 2.1 6.6 16.3 7.6 6.2 12.3 0.5 13.1 26.8 1.1 0.3 35.3 11.4 19.2 27.3 9.0 8.8 43.7 27.1 20.8 19.6 41.1 0.2 4.0 200.0 13.6 4.3 24.9 0.8 4.9 2.2 5.1 4.5 3.3 3.3 4.5 3.8 2.6 5.6 2.4 2.9 18.9 4.8 4.6 5.3 1.8 1.9 6.7 8.9 9.1 9.7 6.1 11.2 15.6 7.9 12.6 6.6 13.8 7.8 104.7 89.8 69.8 357.5 48.5 78.0 84.9 65.0 70.0 9.5 141.8 111.5 143.0 100.1 86.2 69.9 14.6 44.7 65.7 207.1 29.4 139.7 566.5 49.3 134.4 91.8 77.5 12.0 132.8 90.9 24.1 124.9 97.9 93.6 18.3 136.6 126.4 94.8 42.5 5.0 191.2 91.7 44.7 65.1 121.0 1737.1 225.3 75.8 80.0 308.2 55.8 24.8 54.6 395.6 214.9 120.2 158.1 476.9 24.6 172.5 127.5 80.2 60.9 7.1 335.2 159.2 368.2 9.8 8.0 64.2 68.2 18.6 55.3 46.8 151.3 149.3 LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753120 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 104.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 11 "NTERA-2: 15.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA070726 Uncertain "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "Endoplasmic reticulum" "HPA070726: " "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (4.75e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.65e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-4)" "unprognostic (4.49e-6)" "unprognostic (6.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" 0.2 0.2 0.6 0.2 0.7 0.5 0.4 0.7 2.6 0.2 1.6 0.5 1.2 0.1 0.3 0.0 0.2 0.5 0.1 0.7 1.2 0.1 2.1 0.3 0.1 1.0 1.1 0.3 0.8 0.2 0.2 0.1 1.3 0.4 0.1 1.0 0.1 0.5 0.8 0.4 1.6 0.1 0.7 0.1 0.3 0.8 0.7 0.0 1.5 0.0 0.1 0.1 0.1 0.9 0.5 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.3 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 15.3 0.0 0.0 0.0 0.0 0.1 1.4 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.6 1.9 0.1 0.1 0.6 0.1 0.1 0.1 0.1 1.5 0.2 0.1 0.1 0.8 0.2 0.2 0.2 0.1 2.2 0.6 0.7 0.7 2.6 0.7 1.2 1.0 1.1 1.3 0.7 0.7 0.9 0.2 0.0 4.4 4.6 0.1 1.1 4.4 4.0 0.6 0.5 8.6 9.1 0.3 11.5 1.7 0.0 0.0 0.1 0.3 0.8 3.9 1.2 15.2 0.9 0.5 0.3 0.0 0.0 2.2 0.8 0.1 1.5 2.0 2.2 0.0 104.4 1.4 2.2 0.1 0.0 0.6 0.9 2.0 0.8 2.8 3.2 0.0 0.3 5.4 0.0 0.0 3.9 0.0 1.0 2.2 1.2 0.0 0.0 0.0 2.4 12.3 1.0 0.9 0.8 0.0 1.4 8.1 10.5 4.7 1.4 1.1 0.3 0.6 0.0 1.2 0.6 LRATD1 "FAM84A, FLJ35392, NSE1" ENSG00000162981 "LRAT domain containing 1" Q96KN4 2 14632700-14650814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 32.2;intestine: 41.0" "Group enriched" "Detected in some" 8 "Cytotrophoblasts: 162.2;Syncytiotrophoblasts: 207.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 35.0" "Group enriched" "Detected in many" 7 "amygdala: 19.7;basal ganglia: 10.8;cerebral cortex: 18.1;hippocampal formation: 13.0;white matter: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 9.4;hTCEpi: 18.0;RT4: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047703 Uncertain Approved Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA047703: AB_2680123" "unprognostic (1.05e-2)" "unprognostic (9.22e-2)" "unprognostic (2.24e-3)" "unprognostic (1.13e-1)" "unprognostic (4.28e-2)" "unprognostic (7.38e-2)" "unprognostic (2.62e-2)" "unprognostic (1.23e-1)" "unprognostic (1.48e-1)" "unprognostic (4.44e-2)" "unprognostic (1.20e-1)" "unprognostic (9.27e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-1)" "unprognostic (1.58e-1)" "unprognostic (5.57e-3)" "unprognostic (1.36e-1)" 0.5 1.4 19.7 4.9 10.8 0.0 2.4 0.0 18.1 10.6 0.0 41.0 26.3 2.7 32.2 28.6 2.9 3.4 2.1 13.0 2.0 4.0 1.4 3.0 0.2 0.0 0.2 8.2 3.2 5.2 3.3 5.3 0.0 13.6 36.2 0.9 13.9 2.0 0.9 18.5 25.3 2.8 0.0 0.2 3.0 12.3 1.4 1.3 2.2 0.1 1.4 14.8 16.6 6.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 2.5 0.6 0.5 0.0 0.3 0.0 0.0 0.3 0.0 9.4 1.0 4.2 1.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 18.0 0.0 5.9 0.2 0.0 0.0 0.0 0.0 1.3 7.8 0.0 0.2 0.8 0.0 4.0 0.0 0.0 0.1 6.9 49.3 4.3 2.0 0.0 1.8 0.0 0.3 0.0 0.0 2.9 8.2 0.7 0.0 3.2 0.0 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 10.8 0.0 18.1 13.0 2.0 0.0 0.2 0.0 0.0 1.4 6.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 162.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 22.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 207.8 0.0 0.0 0.0 0.0 LRBA "BGL, CDC4L, LAB300, LBA" ENSG00000198589 "LPS responsive beige-like anchor protein" P50851 4 150264435-151015727 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 213.7;Inhibitory neurons: 192.6;Microglial cells: 161.1;Oligodendrocyte precursor cells: 239.8;Oligodendrocytes: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019366, HPA023597" Approved Approved "Golgi apparatus,Cytosol" NA NA 340000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus" Cytosol "HPA019366: AB_2138441, HPA023597: AB_1853256" "unprognostic (2.60e-1)" "unprognostic (4.70e-2)" "unprognostic (1.64e-3)" "unprognostic (4.49e-3)" "unprognostic (4.38e-1)" "unprognostic (8.65e-2)" "unprognostic (5.88e-2)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (6.92e-2)" "unprognostic (2.29e-2)" "unprognostic (5.88e-2)" "prognostic favorable (2.22e-16)" "unprognostic (7.15e-2)" "unprognostic (2.36e-1)" "unprognostic (4.79e-1)" "unprognostic (3.00e-1)" 7.3 10.7 3.4 9.3 6.9 11.1 22.7 11.1 3.8 13.1 18.6 16.7 13.3 6.9 14.2 13.9 15.2 9.9 8.3 2.9 2.2 23.5 13.4 11.0 15.8 5.1 4.5 8.9 13.5 34.2 6.5 7.0 6.1 20.0 17.4 14.9 13.8 8.9 7.2 19.3 11.5 6.6 3.4 9.6 17.0 9.4 3.7 18.7 19.1 8.9 17.7 12.3 7.0 6.3 27.6 14.3 11.9 11.1 12.2 18.5 17.0 6.0 15.8 10.9 10.2 30.9 35.6 33.7 7.2 8.6 7.5 13.7 22.1 36.6 15.3 25.9 15.8 20.8 19.8 19.0 7.5 29.0 16.2 14.6 21.1 16.0 24.6 23.9 32.9 14.8 22.4 24.3 12.9 21.9 21.9 7.7 10.7 23.7 10.3 18.4 12.0 12.6 42.0 33.7 39.3 13.0 15.1 32.1 7.4 18.1 32.4 6.1 17.2 16.8 12.2 8.7 11.4 20.9 20.5 20.5 26.2 16.0 6.6 5.7 0.6 1.2 5.0 0.2 3.3 4.9 3.3 4.7 1.0 2.1 2.3 4.0 0.1 3.2 2.1 2.1 4.6 1.8 3.4 6.9 11.1 3.8 2.9 2.2 5.1 4.5 6.1 3.4 3.7 6.3 10.4 16.0 14.9 148.5 42.5 17.5 16.4 21.0 28.5 33.5 30.8 18.2 55.9 21.5 21.5 51.5 148.0 23.7 37.7 19.7 9.8 15.2 25.5 51.2 11.0 13.3 42.0 40.2 213.7 13.5 10.6 12.8 56.6 61.8 6.3 22.4 10.0 20.5 6.1 30.3 192.6 23.8 24.4 11.1 12.8 5.5 9.6 17.7 16.0 161.1 8.2 17.7 46.4 239.8 217.4 17.2 20.2 10.1 38.3 22.4 22.0 15.8 36.7 72.6 6.6 13.7 9.8 16.6 22.3 37.3 23.7 24.2 45.6 25.9 27.2 24.0 LRCH2 KIAA1495 ENSG00000130224 "Leucine rich repeats and calponin homology domain containing 2" Q5VUJ6 X 115110616-115234096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 23.8;Excitatory neurons: 24.4;Inhibitory neurons: 38.0;Oligodendrocyte precursor cells: 48.2;Oligodendrocytes: 32.0;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 21.4;U-266/70: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003233, HPA076892" Approved Approved "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003233: AB_2265929, HPA076892: " "unprognostic (9.74e-2)" "unprognostic (9.48e-2)" "unprognostic (1.14e-2)" "unprognostic (4.22e-5)" "unprognostic (2.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (9.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (1.01e-2)" "unprognostic (1.84e-1)" "unprognostic (4.29e-5)" "unprognostic (1.09e-3)" "unprognostic (1.34e-1)" "unprognostic (7.75e-2)" "unprognostic (1.16e-2)" 2.7 4.4 3.9 1.4 4.1 0.0 2.0 4.2 4.7 5.2 0.6 8.2 0.5 5.1 2.1 1.6 3.4 2.6 2.6 4.0 6.8 1.1 0.2 2.8 0.7 3.3 3.8 7.0 0.5 0.3 4.4 7.5 3.5 8.3 1.9 3.6 0.5 7.3 0.5 0.5 2.0 5.1 3.9 1.8 2.0 2.1 6.2 0.5 2.3 1.5 0.2 4.9 3.3 4.3 0.0 0.0 6.4 4.7 6.4 5.3 0.0 4.3 9.2 4.1 9.3 0.0 0.0 0.1 0.1 5.7 3.2 0.3 21.4 0.0 6.2 0.0 5.8 0.0 0.0 0.0 5.1 0.0 0.1 3.1 0.0 1.6 0.3 10.8 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 6.2 0.0 4.6 0.0 5.1 0.6 0.0 8.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 2.5 0.1 6.0 14.0 2.5 0.0 1.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.1 4.2 4.7 4.0 6.8 3.3 3.8 3.5 3.9 6.2 4.3 9.3 3.2 12.3 23.8 0.0 0.6 0.1 0.0 0.6 6.9 0.1 0.3 7.5 0.0 0.0 1.8 0.0 0.1 0.0 0.0 1.9 0.0 9.1 0.1 5.9 6.7 0.0 0.0 24.4 0.0 0.2 6.3 0.0 0.1 0.0 8.4 2.9 0.0 0.6 1.7 38.0 0.0 0.0 0.0 1.0 2.9 8.7 0.1 1.8 9.4 0.0 6.4 0.0 48.2 32.0 0.0 0.0 6.4 0.0 1.2 0.0 0.0 0.0 2.5 26.3 3.6 7.8 5.4 2.9 0.0 0.1 0.3 0.2 5.7 0.0 0.1 LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;cervix: 10.1;parathyroid gland: 11.1" "Group enriched" "Detected in some" 19 "Excitatory neurons: 873.9;Inhibitory neurons: 581.5;Oligodendrocyte precursor cells: 296.1" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 16.4;HSkMC: 3.1;RPTEC TERT1: 5.2;SCLC-21H: 8.8;U-138 MG: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" 1.4 2.2 5.3 1.0 7.5 0.0 1.4 0.0 16.5 10.1 0.0 2.0 0.2 2.5 0.6 0.5 3.3 1.0 0.6 7.9 5.9 0.2 0.3 0.7 0.0 0.8 1.4 1.6 0.3 11.1 0.8 1.1 4.9 2.4 1.0 2.6 0.3 6.4 0.2 0.6 0.4 1.5 0.8 0.6 0.7 0.9 2.0 0.3 0.5 0.5 0.2 6.1 5.2 4.3 0.0 0.0 1.7 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 8.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.5 0.0 16.5 7.9 5.9 0.8 1.4 4.9 0.8 2.0 4.3 0.5 0.0 0.0 29.7 0.0 0.3 0.0 0.0 0.0 8.2 0.1 0.6 1.0 2.8 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.2 0.3 7.8 0.9 0.0 0.0 873.9 0.0 0.1 7.9 0.0 0.6 0.0 0.2 0.0 0.5 0.1 0.0 581.5 0.0 0.0 0.0 0.8 1.7 8.4 0.1 1.8 24.4 0.0 0.4 0.0 296.1 11.8 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.4 1.5 0.0 2.1 0.0 0.3 0.1 0.2 2.1 0.0 0.1 LRIT2 "AC022389.4, LRRC22" ENSG00000204033 "Leucine rich repeat, Ig-like and transmembrane domains 2" A6NDA9 10 84220571-84225544 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "retina: 59.0" "Group enriched" "Detected in some" 4 "Bipolar cells: 7.5;Cone photoreceptor cells: 8.4;Rod photoreceptor cells: 24.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA037788 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA037788: AB_10672393" "unprognostic (3.12e-1)" "unprognostic (1.09e-3)" "unprognostic (3.99e-1)" "unprognostic (9.44e-2)" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.5 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 59.0 0.0 0.0 0.0 3.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.3 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 31.3;Granulosa cells: 68.6;Leydig cells: 101.9;Peritubular cells: 31.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cell line enriched" "Detected in many" 5 "LHCN-M2: 1237.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" 8.1 2.4 1.6 1.1 1.7 0.2 12.9 1.6 2.4 22.5 1.7 2.7 1.6 15.7 12.1 6.0 17.3 27.4 13.2 1.7 1.6 2.8 3.5 3.2 2.1 1.6 1.7 76.2 2.3 2.0 2.4 0.6 1.5 5.6 3.3 1.8 2.7 3.2 2.1 3.0 2.3 6.0 1.6 3.3 6.9 5.0 2.3 6.2 3.8 2.8 1.0 4.4 5.8 1.6 0.0 0.0 58.8 0.5 6.0 29.4 0.1 1.6 18.2 0.6 2.8 0.0 0.2 0.0 3.4 1.5 7.3 0.1 0.0 0.0 4.3 0.0 1.4 0.1 0.0 0.1 8.3 0.5 0.2 28.1 0.7 21.5 0.0 141.1 140.9 0.6 0.0 0.1 1237.5 0.0 0.1 0.4 3.1 0.1 0.1 0.1 244.0 0.2 0.2 0.1 1.3 1.3 0.1 0.0 0.1 0.1 0.0 1.7 11.8 0.2 1.5 15.2 2.3 1.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 1.6 2.4 1.7 1.6 1.6 1.7 1.5 1.6 2.3 1.6 3.6 0.0 1.1 4.6 0.2 0.9 0.2 0.9 0.0 3.7 0.7 0.8 1.1 0.0 0.5 1.8 2.1 0.3 0.3 0.0 0.0 1.7 3.5 2.7 15.3 4.4 0.0 0.0 6.9 0.4 0.2 31.3 1.1 4.6 1.3 68.6 6.1 0.5 0.4 0.0 8.7 0.1 2.0 0.0 2.7 2.9 101.9 0.5 5.4 10.3 0.6 0.6 0.0 2.5 5.3 0.2 0.3 31.6 0.0 0.3 0.1 0.3 0.1 2.2 65.7 16.1 17.8 0.6 0.5 0.4 0.6 0.0 0.9 6.6 0.2 0.2 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LRRC36 FLJ11004 ENSG00000159708 "Leucine rich repeat containing 36" Q1X8D7 16 67326798-67385204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 35.3" "Group enriched" "Detected in some" 7 "Alveolar cells type 2: 94.7;Early spermatids: 192.8;Late spermatids: 118.0;Spermatocytes: 68.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "plasmacytoid DC: 9.7" "Lineage enriched" "Detected in many" 7 "dendritic cells: 9.7" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 1.4;JURKAT: 1.3;TIME: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA058479 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 83: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "HPA058479: AB_2683728" "unprognostic (4.59e-2)" "unprognostic (6.84e-2)" "unprognostic (2.17e-2)" "unprognostic (2.26e-5)" "unprognostic (5.27e-2)" "unprognostic (4.32e-2)" "unprognostic (5.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.99e-2)" "unprognostic (1.65e-1)" "unprognostic (3.32e-3)" "unprognostic (4.49e-2)" "unprognostic (1.36e-1)" "unprognostic (1.26e-1)" "unprognostic (3.70e-1)" "unprognostic (1.99e-1)" "unprognostic (3.88e-2)" 0.1 0.0 0.2 0.0 0.3 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 3.0 0.1 0.0 0.1 0.4 0.3 0.0 4.9 0.2 0.4 0.3 0.1 0.3 0.0 0.1 6.1 0.3 0.0 0.5 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 35.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.2 0.3 0.2 0.2 0.1 0.4 0.4 0.3 0.3 0.1 0.2 0.0 0.4 3.2 94.7 0.0 0.3 0.3 0.4 0.2 0.0 0.8 0.3 0.3 0.7 0.0 0.8 0.0 0.0 0.1 6.7 0.5 0.0 1.9 192.8 15.4 0.2 3.2 2.4 0.0 1.2 0.0 0.1 1.4 0.0 0.4 8.8 1.5 0.0 0.0 0.2 0.0 2.6 0.6 0.0 0.0 0.7 118.0 2.1 0.7 7.2 1.9 0.7 1.5 0.0 2.0 0.4 0.1 0.3 1.5 0.0 0.1 0.5 1.3 12.0 0.2 0.0 0.7 0.4 68.2 15.1 0.0 0.3 0.3 0.3 0.6 1.7 0.3 LRRC61 "FLJ31392, HSPC295, MGC3036" ENSG00000127399 "Leucine rich repeat containing 61" Q9BV99 7 150323263-150338156 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 80.6;Hep G2: 53.3;NTERA-2: 67.0" "Low region specificity" "Detected in all" HPA019355 Approved Approved Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA019355: AB_1853339" "unprognostic (4.05e-2)" "unprognostic (9.50e-2)" "unprognostic (1.61e-3)" "unprognostic (5.91e-3)" "prognostic unfavorable (1.11e-5)" "unprognostic (1.46e-2)" "unprognostic (4.43e-3)" "unprognostic (1.82e-1)" "unprognostic (1.76e-2)" "unprognostic (4.22e-2)" "unprognostic (2.53e-2)" "unprognostic (1.56e-1)" "unprognostic (1.66e-2)" "prognostic favorable (2.85e-4)" "unprognostic (1.21e-1)" "unprognostic (3.27e-1)" "unprognostic (1.69e-3)" 4.0 18.3 9.5 4.5 8.4 1.6 4.5 6.9 8.7 7.5 9.8 5.7 4.3 6.5 2.0 8.8 14.5 4.0 4.1 7.7 13.1 12.1 23.4 4.4 7.3 9.7 10.1 15.2 11.2 11.4 13.5 3.8 10.4 6.6 1.9 2.8 5.3 4.3 2.2 6.8 5.8 2.0 8.2 6.1 6.1 9.1 13.4 11.5 8.7 2.3 3.9 4.7 6.5 6.7 20.0 0.5 0.6 0.1 0.0 0.0 9.0 0.2 0.0 2.4 7.8 37.9 19.4 6.2 8.2 0.3 0.0 17.6 0.0 0.0 1.3 80.6 24.4 7.4 23.5 53.3 13.8 0.0 3.7 1.6 7.9 0.0 0.0 0.6 0.1 40.2 25.9 11.5 0.0 36.5 37.5 3.2 67.0 13.8 0.0 0.0 0.1 16.5 5.7 13.2 34.6 33.4 33.6 7.2 13.7 5.6 5.6 4.5 0.1 0.0 0.1 0.0 0.1 12.5 4.4 0.0 0.0 0.0 0.0 2.8 2.9 8.5 10.8 1.1 8.3 8.7 7.3 8.2 3.0 10.7 7.0 8.4 13.1 8.7 1.3 17.9 12.7 5.7 9.5 8.4 6.9 8.7 7.7 13.1 9.7 10.1 10.4 8.2 13.4 6.7 0.3 6.4 1.5 2.3 7.1 1.1 4.7 16.5 8.6 7.8 8.0 8.9 2.2 11.5 6.8 16.5 0.0 25.2 11.1 9.4 19.6 27.3 5.7 20.9 1.6 1.7 19.3 3.8 1.7 28.4 24.5 4.7 7.1 5.8 1.3 22.9 1.8 22.6 6.0 13.5 3.6 6.7 18.3 1.3 0.0 16.3 10.2 3.3 3.6 0.0 16.5 13.7 11.3 4.5 0.3 27.9 11.2 5.7 3.5 4.0 11.7 48.7 20.1 4.5 0.0 5.3 3.2 20.8 23.7 8.1 2.7 27.0 7.4 9.0 10.6 3.0 LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 62.1;Leydig cells: 27.1;Melanocytes: 33.8;Peritubular cells: 17.3;Skeletal myocytes: 33.0" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 7.7;ASC TERT1: 25.3;HHSteC: 19.8;HSkMC: 10.6;LHCN-M2: 13.4" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" 23.3 6.6 0.4 2.5 0.4 0.5 16.0 1.5 1.3 22.4 2.6 15.1 1.8 29.7 3.7 4.5 18.2 3.6 7.2 0.6 0.6 1.0 0.1 3.5 0.5 0.5 0.3 21.0 1.1 0.3 1.7 0.7 0.4 6.1 2.1 0.4 5.5 5.8 4.8 10.6 7.2 9.1 0.2 0.2 8.2 1.5 0.5 0.4 4.2 5.6 0.3 9.7 16.1 0.7 0.0 0.1 0.2 0.3 7.7 25.3 0.3 2.8 4.0 0.3 1.4 0.2 0.1 0.2 0.3 4.6 0.1 0.3 0.1 0.0 0.4 0.2 0.2 0.5 0.2 0.2 19.8 0.2 0.2 10.6 0.1 0.6 0.0 0.2 0.1 0.4 0.3 0.1 13.4 0.1 0.3 0.6 0.6 0.1 0.1 0.1 1.7 0.3 0.0 0.2 0.8 0.3 0.4 0.3 0.8 0.1 0.2 0.3 0.3 2.4 0.2 2.7 0.1 0.2 0.2 0.3 1.5 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.0 0.4 0.4 1.5 1.3 0.6 0.6 0.5 0.3 0.4 0.2 0.5 0.7 4.0 0.0 1.8 0.0 0.1 6.6 2.1 0.0 0.0 2.1 0.5 0.8 1.5 0.0 0.6 0.0 2.1 0.1 0.2 0.0 0.0 0.0 1.0 0.5 11.0 3.7 1.2 0.0 0.1 0.0 0.2 62.1 0.5 0.4 1.3 0.2 1.4 0.1 0.4 1.7 0.3 0.3 0.0 0.6 8.3 0.5 27.1 1.1 33.8 1.9 0.1 0.2 1.0 0.0 0.1 0.0 0.1 17.3 0.4 1.4 0.1 0.3 0.0 1.0 0.0 33.0 2.8 0.4 0.3 0.5 7.0 0.1 1.1 1.2 0.1 1.3 LSP1 WP34 ENSG00000130592 "Lymphocyte specific protein 1" P33241 11 1850904-1892267 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 224.7;lymphoid tissue: 245.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 492.2;Langerhans cells: 553.6;monocytes: 1505.6;NK-cells: 352.2;Plasma cells: 338.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 278.5;HDLM-2: 978.9;Karpas-707: 215.4;RPMI-8226: 500.2;U-937: 173.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017781, HPA019693" Enhanced NA NA 1600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB017781: , HPA019693: AB_1853387" "unprognostic (7.53e-3)" "prognostic favorable (3.56e-4)" "unprognostic (4.35e-2)" "prognostic favorable (2.54e-4)" "prognostic unfavorable (5.35e-4)" "unprognostic (1.43e-3)" "unprognostic (3.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.72e-1)" "unprognostic (1.03e-3)" "unprognostic (3.29e-1)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.20e-2)" 75.6 224.7 2.1 148.8 2.6 167.3 51.2 2.4 6.4 63.8 5.3 39.2 33.6 36.8 3.8 42.5 41.7 32.6 48.2 3.8 3.4 6.4 12.1 49.8 154.8 6.0 2.6 5.3 10.7 3.8 7.4 21.8 4.5 13.4 22.3 1.0 52.8 8.1 28.4 98.0 76.6 12.5 4.3 245.0 52.1 8.1 6.0 65.5 24.7 29.4 85.0 83.7 51.4 11.6 0.3 1.2 0.0 0.0 41.0 125.2 0.4 0.0 0.0 0.0 0.0 0.1 0.2 278.5 1.5 0.2 0.3 0.4 0.0 0.0 0.0 978.9 0.0 0.5 0.2 0.4 7.9 1.0 0.9 32.0 0.5 0.1 1.3 0.4 0.1 2.2 0.9 215.4 24.7 0.1 19.6 28.2 0.5 0.0 0.0 1.1 13.6 500.2 0.0 0.0 0.4 3.3 0.2 0.0 0.3 0.0 0.3 0.9 0.5 0.7 4.6 0.3 0.8 1.0 0.7 38.4 0.4 173.0 0.3 365.1 803.6 785.5 384.3 863.3 222.6 452.1 249.1 346.8 896.6 298.8 161.3 260.8 1574.3 279.6 888.2 669.7 491.4 1293.0 2.1 2.6 2.4 6.4 3.8 3.4 6.0 2.6 4.5 4.3 6.0 11.6 18.3 16.0 7.9 0.0 312.8 118.3 14.0 43.0 76.8 0.8 3.9 4.3 2.7 8.6 37.6 3.7 0.0 3.6 295.4 0.4 1.9 1.3 3.4 1.2 13.3 11.4 1.2 40.6 0.2 8.9 4.4 160.4 15.3 1.4 12.6 0.9 11.0 2.3 492.2 1.7 0.2 0.8 16.2 118.4 553.6 7.8 89.8 310.9 65.8 0.0 1505.6 0.2 352.2 0.5 0.1 1.4 1.4 30.1 338.4 1.1 1.2 12.9 36.6 1.0 0.0 182.1 15.9 0.4 1.3 16.7 114.7 6.4 310.1 92.7 3.2 67.3 LTA4H ENSG00000111144 "Leukotriene A4 hydrolase" P09960 12 96000753-96043520 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Leukotriene biosynthesis, Lipid metabolism" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 207.2;Kupffer cells: 255.8;monocytes: 245.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008399, CAB015221, HPA017017" Supported Approved Nucleoplasm,Cytosol NA NA 86000000 "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB015221: , HPA008399: AB_1852816, HPA017017: AB_1852818" "prognostic favorable (9.79e-4)" "unprognostic (6.62e-2)" "unprognostic (6.04e-2)" "unprognostic (1.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (4.25e-3)" "prognostic favorable (8.96e-4)" "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (3.38e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-1)" 40.2 66.9 24.6 64.5 25.5 180.4 53.6 29.4 30.6 55.6 33.8 48.2 78.1 51.1 38.4 110.1 61.7 40.3 35.5 25.0 27.8 58.1 43.9 190.8 64.1 26.3 25.4 110.5 54.9 53.3 37.4 27.4 26.0 41.1 49.6 36.9 41.2 40.9 45.0 67.8 60.5 58.3 25.7 57.8 46.6 19.9 28.1 49.2 49.4 45.0 96.4 51.9 52.7 33.0 85.2 90.4 123.5 73.4 104.2 115.1 53.8 33.7 101.8 67.5 78.1 66.6 72.0 190.0 42.0 51.9 52.8 108.3 103.4 140.1 92.3 63.3 97.0 68.5 54.3 81.8 61.8 35.7 39.4 110.1 118.4 91.9 114.5 305.3 134.9 101.1 42.9 32.5 98.7 59.2 96.7 115.0 145.8 100.7 115.5 88.9 90.5 109.7 125.7 107.7 63.9 75.5 64.2 80.4 78.3 95.1 98.7 44.7 49.0 28.3 47.6 40.2 38.2 42.8 79.4 85.4 19.1 66.2 22.3 4.4 662.9 17.7 33.4 699.2 63.4 126.1 46.6 43.4 282.3 157.5 65.0 50.5 46.0 120.4 638.8 70.4 51.2 591.5 24.6 25.5 29.4 30.6 25.0 27.8 26.3 25.4 26.0 25.7 28.1 33.0 32.8 38.5 135.0 15.3 82.8 51.9 64.8 96.6 52.3 21.4 41.8 41.1 25.3 25.8 110.2 38.6 33.3 29.3 47.9 17.6 74.3 42.9 74.3 18.4 20.8 38.2 21.6 50.5 21.3 28.0 28.2 29.7 38.2 27.3 7.6 31.5 57.8 21.7 207.2 11.8 18.5 40.4 40.7 255.8 76.6 16.4 36.7 183.3 21.4 10.3 245.5 35.5 26.8 19.6 17.5 20.8 27.1 41.0 40.1 35.4 73.2 69.3 45.0 55.6 6.6 26.7 35.4 46.9 11.6 108.0 74.9 20.8 39.1 32.9 70.4 49.7 LTB "p33, TNFC, TNFSF3" ENSG00000227507 "Lymphotoxin beta" Q06643 6 31580525-31582522 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 66.7;lymphoid tissue: 229.2" "Cell type enhanced" "Detected in many" "B-cells: 1087.8;dendritic cells: 183.5;Ductal cells: 280.4;Pancreatic endocrine cells: 296.2;T-cells: 554.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.6;Daudi: 127.4;HDLM-2: 82.2;HMC-1: 38.1;NB-4: 62.3;REH: 58.6;U-698: 90.8" "Not detected" "Not detected" HPA048884 Approved Approved Centrosome NA NA "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA048884: AB_2680543" "unprognostic (1.43e-2)" "unprognostic (3.89e-2)" "unprognostic (7.29e-2)" "prognostic favorable (2.36e-6)" "unprognostic (2.91e-3)" "prognostic favorable (1.74e-4)" "unprognostic (1.45e-1)" "unprognostic (9.49e-3)" "unprognostic (1.42e-3)" "unprognostic (4.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (8.91e-2)" "unprognostic (4.92e-2)" "unprognostic (6.56e-3)" "unprognostic (1.99e-1)" 3.5 0.7 0.2 82.6 0.3 19.1 1.3 0.1 0.5 1.3 0.2 6.7 8.2 1.2 0.0 4.3 1.2 4.8 1.1 0.1 0.2 10.3 4.8 8.7 103.9 0.4 0.2 0.4 2.5 0.2 0.7 0.9 0.3 2.4 2.7 0.0 4.2 0.3 1.0 2.2 66.7 1.9 0.2 229.2 13.9 0.2 0.3 83.3 3.8 1.4 47.6 8.7 1.4 0.2 18.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 35.6 127.4 1.8 0.0 0.2 0.0 0.0 0.0 0.0 82.2 0.0 1.4 0.0 0.0 0.0 0.4 38.1 0.0 0.0 0.0 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.0 18.5 62.3 0.0 0.0 0.0 58.6 0.0 11.4 32.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.7 0.0 0.0 0.5 0.0 0.0 0.0 0.8 90.8 0.0 0.0 0.0 79.2 9.2 542.5 95.7 55.9 646.7 1027.3 924.3 419.4 14.5 1021.9 713.6 317.0 327.8 142.5 94.5 412.0 672.0 308.9 0.2 0.3 0.1 0.5 0.1 0.2 0.4 0.2 0.3 0.2 0.3 0.2 3.0 0.0 9.0 1.3 1087.8 16.3 0.5 45.7 2.2 0.7 2.9 3.7 0.5 2.8 4.7 90.1 0.0 0.9 183.5 0.9 1.9 280.4 3.5 2.2 2.0 8.4 0.0 11.2 0.9 113.1 0.3 6.3 3.1 1.5 14.0 0.1 10.8 3.5 10.1 0.0 0.9 0.4 160.7 31.0 112.1 0.2 0.6 49.8 42.7 0.0 72.3 1.8 99.9 0.0 0.3 296.2 1.6 0.0 13.6 3.0 0.0 11.6 0.9 0.2 6.6 1.3 4.3 0.4 1.2 1.2 12.4 0.3 554.0 0.3 3.6 0.3 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 966.4;Fibroblasts: 2136.1;Leydig cells: 401.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 1991.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 161.5 133.5 0.6 68.1 0.7 0.3 153.2 0.6 5.6 199.8 4.2 85.0 56.1 301.0 88.3 75.7 59.2 739.0 183.8 0.7 0.9 85.0 34.6 211.4 41.3 0.9 0.8 92.9 72.9 26.3 5.3 535.9 0.8 115.2 133.0 5.7 14.3 67.4 9.6 20.0 90.6 354.5 0.7 4.8 47.1 17.5 1.3 13.4 30.8 73.0 80.3 486.0 39.2 0.8 0.0 0.3 6.9 0.0 237.4 115.9 0.7 400.8 1991.0 16.0 24.3 0.0 0.1 0.0 0.0 339.9 0.0 0.6 0.0 0.0 5.4 0.0 0.0 0.0 21.5 0.0 183.7 0.6 0.1 160.5 0.0 33.7 1.0 0.9 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 1.2 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.3 14.9 0.1 0.0 10.8 16.3 0.0 0.0 0.0 17.0 4.5 14.3 0.0 0.2 0.0 0.0 8.8 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.6 5.6 0.7 0.9 0.9 0.8 0.8 0.7 1.3 0.8 77.5 12.8 30.9 0.0 0.6 97.6 1.2 0.8 3.4 0.2 9.4 8.6 15.2 0.0 5.0 0.0 2.1 44.9 4.0 0.1 0.0 0.7 3.5 27.0 966.4 27.2 0.0 0.0 0.0 0.0 38.9 2136.1 8.6 15.2 18.3 0.0 55.0 0.3 63.6 0.0 0.2 0.3 0.0 0.3 143.5 8.7 401.7 9.5 117.4 16.9 1.0 86.9 0.0 0.0 0.0 2.1 0.0 44.8 6.3 4.9 0.4 0.3 0.8 3.0 0.0 39.1 165.5 0.2 0.9 5.9 100.2 84.0 14.5 27.4 0.0 4.1 LURAP1L "bA3L8.2, C9orf150, FLJ38505, LRAP35b, MGC46502" ENSG00000153714 "Leucine rich adaptor protein 1 like" Q8IV03 9 12775020-12823060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 90.2;Paneth cells: 88.8;Prostatic glandular cells: 104.3;Urothelial cells: 140.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 100.6;hTERT-HME1: 81.9;T-47d: 118.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024407 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoli Nucleoplasm "HPA024407: AB_10603780" "unprognostic (1.20e-1)" "unprognostic (2.15e-1)" "unprognostic (7.45e-2)" "unprognostic (1.73e-2)" "unprognostic (2.08e-2)" "unprognostic (5.61e-3)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" "unprognostic (2.92e-1)" "unprognostic (1.06e-2)" "unprognostic (1.56e-2)" "unprognostic (3.67e-2)" "unprognostic (5.68e-3)" "unprognostic (4.38e-1)" "unprognostic (5.67e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-2)" 14.6 9.3 3.4 5.5 4.6 0.1 10.6 11.8 6.1 10.9 2.5 19.9 4.1 6.2 3.3 4.6 6.6 11.8 4.4 3.5 4.2 5.4 32.2 25.0 3.9 5.2 4.6 4.2 19.6 0.8 5.5 21.0 5.0 6.9 9.4 4.7 27.7 6.7 2.5 12.2 9.2 8.3 5.7 10.4 12.5 0.5 4.7 1.2 8.7 3.4 2.0 12.1 12.4 5.8 2.2 7.1 0.0 2.3 11.0 15.1 0.0 3.9 20.2 5.1 5.4 0.0 2.6 0.0 1.5 20.6 24.3 3.0 0.0 0.4 3.9 0.0 0.8 1.1 6.7 4.0 100.6 0.0 0.0 6.0 9.7 17.4 81.9 8.6 3.3 0.0 0.0 25.8 3.1 1.8 0.0 0.0 0.1 9.6 7.8 0.0 1.3 0.1 20.7 1.2 15.5 1.5 4.7 2.9 3.8 1.7 118.5 0.4 1.3 4.5 0.7 11.7 2.8 0.1 0.0 0.0 7.2 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.4 4.6 11.8 6.1 3.5 4.2 5.2 4.6 5.0 5.7 4.7 5.8 9.6 9.6 18.4 1.3 0.7 90.2 34.4 19.3 5.2 10.2 60.1 26.2 7.1 20.0 40.2 1.8 2.1 1.0 0.5 58.7 7.9 66.6 5.0 11.5 3.2 7.8 26.7 0.0 18.4 11.8 2.7 19.7 10.2 29.2 10.8 12.9 1.8 30.2 0.6 18.5 41.6 12.8 24.4 0.0 8.4 0.8 9.3 2.3 26.6 6.5 0.0 4.3 0.0 8.0 44.1 27.5 88.8 3.0 0.0 104.3 20.7 5.5 16.1 10.2 39.5 8.0 47.4 0.1 0.6 2.9 64.4 1.1 1.9 1.3 49.5 140.4 LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 570.8;Kupffer cells: 544.6;Langerhans cells: 155.4;Macrophages: 198.5;monocytes: 136.0;Plasma cells: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 627.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 627.0" "Cell line enhanced" "Detected in many" "GAMG: 75.1;Karpas-707: 184.9;RPMI-8226: 94.0;U-87 MG: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" NA NA 250000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA053060: AB_2682029" "unprognostic (2.96e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.38e-11)" "unprognostic (2.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" 28.6 12.4 12.9 42.4 13.5 17.9 24.7 13.1 22.7 12.9 13.8 15.7 12.3 10.5 5.4 9.0 11.1 35.3 9.5 13.0 14.4 13.2 22.8 22.0 47.4 16.3 14.8 22.6 3.7 2.4 8.0 44.9 14.9 6.1 14.5 1.2 11.4 6.7 3.8 4.4 9.9 20.3 14.7 59.6 10.6 4.7 13.9 16.2 7.3 9.8 39.3 30.5 7.9 17.1 1.5 0.0 0.3 0.2 34.5 73.2 0.1 49.5 61.9 13.5 31.1 0.0 0.5 15.9 16.7 32.6 75.1 0.5 0.2 0.6 34.4 17.1 0.3 0.3 0.0 1.8 17.5 2.7 0.9 21.2 0.4 21.9 4.3 2.2 67.2 9.7 0.2 184.9 48.9 0.0 6.5 2.1 0.2 0.0 1.0 6.4 0.0 94.0 2.5 0.0 0.3 0.2 0.0 0.2 6.5 0.3 0.0 3.3 52.1 33.5 2.6 18.0 12.1 48.1 24.7 9.6 92.3 1.0 14.7 13.7 90.2 0.4 0.5 85.1 1.3 26.3 12.8 1.9 45.8 15.1 8.2 2.9 627.0 0.2 71.8 37.6 21.6 30.6 12.9 13.5 13.1 22.7 13.0 14.4 16.3 14.8 14.9 14.7 13.9 17.1 35.1 16.0 10.7 0.0 48.4 13.8 1.2 1.3 0.0 0.2 11.2 4.4 2.4 0.0 9.7 3.7 0.0 2.7 16.3 0.1 0.0 6.8 24.2 0.3 1.0 63.6 0.0 14.1 2.8 7.4 3.1 32.9 0.0 0.3 3.8 0.0 104.2 3.3 570.8 0.0 3.9 0.0 2.0 544.6 155.4 3.1 14.3 198.5 76.5 21.5 136.0 0.0 1.0 0.5 1.1 9.4 0.0 6.8 172.6 0.8 0.0 1.1 5.6 0.2 6.6 20.0 14.0 0.7 0.2 2.2 11.6 6.4 21.8 12.4 0.3 1.4 LYPD3 C4.4A ENSG00000124466 "LY6/PLAUR domain containing 3" O95274 19 43460787-43465608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1066.8;skin 1: 669.3;vagina: 487.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 504.7;Squamous epithelial cells: 811.7;Suprabasal keratinocytes: 2306.1;Syncytiotrophoblasts: 715.8;Urothelial cells: 642.9" "Cancer enhanced" "Detected in many" "cervical cancer: 158.5;head and neck cancer: 235.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 5.5" "Group enriched" "Detected in many" 9 "dendritic cells: 2.6;granulocytes: 2.1;T-cells: 5.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.5;HaCaT: 99.5;MCF7: 114.2;RT4: 108.2;SK-BR-3: 158.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041529, HPA041797, HPA077859" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA 7600000 "Cluster 32: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Vesicles" "HPA041529: AB_2677534, HPA041797: AB_2677679, HPA077859: " "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (2.80e-1)" "unprognostic (2.67e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.20e-1)" "unprognostic (6.99e-2)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (1.07e-3)" "unprognostic (5.13e-2)" "unprognostic (8.79e-2)" "unprognostic (1.11e-1)" "unprognostic (2.96e-3)" 1.7 3.5 0.7 1.7 0.8 6.6 32.1 0.6 1.0 259.1 1.4 1.1 0.5 7.6 1.8 1066.8 3.5 1.3 1.3 0.7 0.9 2.9 1.2 1.6 2.6 0.7 0.8 8.9 1.3 1.8 2.3 12.3 0.7 11.9 0.7 1.0 183.3 1.3 2.8 669.3 1.6 0.8 0.7 2.1 3.3 1.1 0.8 12.2 1.2 0.2 131.9 55.0 487.0 0.7 38.6 0.6 0.2 0.6 0.3 0.0 15.3 1.5 3.9 1.4 1.9 0.5 42.5 0.4 1.7 1.1 5.6 99.5 0.2 4.4 0.7 0.0 0.3 0.7 4.5 0.8 0.4 0.0 0.9 1.7 37.2 0.2 0.3 1.7 0.0 3.1 0.2 0.1 0.1 114.2 0.9 0.0 0.2 24.3 8.3 0.5 0.0 0.2 1.0 108.2 0.1 0.3 0.5 158.9 1.8 4.7 17.7 0.1 0.0 0.0 0.7 0.5 0.7 0.6 3.0 0.1 0.1 0.2 0.1 0.0 0.3 0.0 0.8 0.0 1.1 0.1 2.9 1.1 2.6 0.0 5.5 4.7 2.1 0.0 0.0 0.3 0.9 1.2 0.7 0.8 0.6 1.0 0.7 0.9 0.7 0.8 0.7 0.7 0.8 0.7 0.9 0.0 1.1 0.0 1.3 504.7 102.5 161.2 111.0 0.7 66.6 38.0 0.6 2.8 72.6 14.7 0.0 96.5 2.1 0.9 1.9 1.6 0.1 4.5 4.4 7.5 0.0 0.4 0.0 0.2 87.2 18.1 3.6 24.5 5.7 0.5 0.0 0.3 14.0 3.3 0.1 2.2 24.4 0.3 139.8 0.0 0.6 23.2 147.7 0.0 0.7 4.5 0.0 0.0 0.2 4.7 0.2 0.4 0.0 40.4 0.3 0.7 5.7 0.5 0.0 1.5 10.5 0.1 0.9 811.7 2306.1 715.8 9.6 0.5 1.1 642.9 LYVE1 "LYVE-1, XLKD1" ENSG00000133800 "Lymphatic vessel endothelial hyaluronan receptor 1" Q9Y5Y7 11 10556966-10611689 "Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 126.4;placenta: 149.3" "Group enriched" "Detected in many" 4 "Hepatic stellate cells: 238.8;Hofbauer cells: 807.4;Kupffer cells: 338.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HUVEC TERT2: 81.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.8" "CAB025860, HPA042953" Supported NA NA 3300000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB025860: , HPA042953: AB_2678238" "unprognostic (9.83e-2)" "unprognostic (1.52e-1)" "unprognostic (1.87e-1)" "unprognostic (3.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.53e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.98e-5)" "unprognostic (1.67e-2)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.43e-3)" 126.4 68.9 2.7 19.3 3.5 0.9 37.3 2.0 5.1 17.6 8.9 19.9 13.3 8.1 5.7 26.2 23.0 20.2 13.5 2.9 2.4 8.1 44.2 23.8 8.4 3.0 2.2 11.8 4.9 2.3 2.7 149.3 3.1 4.0 20.0 0.3 5.4 11.2 5.0 7.1 17.6 67.1 2.1 61.6 10.5 4.3 3.3 1.7 13.5 27.4 3.0 35.1 6.8 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 81.6 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 3.5 2.0 5.1 2.9 2.4 3.0 2.2 3.1 2.1 3.3 3.2 5.7 0.0 2.8 8.1 2.1 3.7 0.1 0.0 0.0 0.0 0.5 0.3 4.6 8.6 0.0 0.0 0.0 5.3 0.3 0.0 0.0 0.0 1.0 0.0 0.2 102.7 0.0 5.3 0.8 0.0 5.7 3.4 0.0 0.0 1.3 0.0 238.8 4.5 807.4 0.0 0.4 0.0 0.0 338.1 10.7 2.3 3.7 86.0 7.2 12.2 0.1 0.0 0.0 0.5 0.6 0.0 0.0 0.4 2.7 0.2 0.0 0.0 1.5 0.0 13.1 3.4 6.8 0.0 0.0 1.4 3.3 11.1 1.4 0.7 0.0 0.2 MAB21L3 "C1orf161, FLJ38716" ENSG00000173212 "Mab-21 like 3" Q8N8X9 1 116111755-116135240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.3;esophagus: 7.0;skin 1: 6.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Alveolar cells type 2: 48.3;Club cells: 18.5;granulocytes: 17.7;Oligodendrocytes: 31.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 4.6;EFO-21: 13.4;RT4: 14.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "cerebellum: 6.2" HPA039551 Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "HPA039551: AB_2676565" "unprognostic (9.25e-3)" "unprognostic (3.47e-3)" "unprognostic (1.44e-3)" "unprognostic (5.23e-5)" "unprognostic (2.22e-1)" "unprognostic (2.06e-2)" "unprognostic (5.36e-2)" "unprognostic (3.75e-3)" "unprognostic (1.21e-1)" "unprognostic (7.01e-2)" "unprognostic (2.49e-1)" "unprognostic (4.84e-2)" "unprognostic (1.16e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-1)" "unprognostic (2.52e-1)" "unprognostic (4.61e-2)" 0.1 0.0 0.8 0.1 1.4 0.6 0.3 2.0 5.2 1.7 0.0 1.5 0.2 0.2 0.1 7.0 0.0 0.0 0.0 1.0 0.8 1.3 1.7 0.2 0.1 1.5 2.1 0.1 0.0 0.0 0.0 0.7 3.5 0.8 1.3 1.3 0.8 0.6 0.3 6.2 0.3 0.0 0.5 0.2 0.2 0.4 3.3 0.2 0.1 0.1 0.6 0.6 2.9 5.3 2.6 0.0 0.4 0.2 0.0 0.0 4.6 0.2 0.1 0.0 0.0 0.3 0.7 1.8 13.4 0.0 0.1 2.5 0.1 0.1 0.0 0.4 0.0 0.4 0.2 2.7 0.0 0.5 0.2 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.5 1.3 0.0 0.2 0.2 0.2 1.1 0.4 0.9 0.4 0.5 0.2 0.5 14.4 0.3 0.3 2.0 1.4 0.3 1.4 1.6 0.3 0.2 0.6 1.1 0.3 0.2 1.2 2.2 0.7 0.3 0.2 0.7 0.9 0.3 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.6 0.1 0.1 1.5 1.2 0.1 0.3 0.0 0.0 0.8 1.4 2.0 5.2 1.0 0.8 1.5 2.1 3.5 0.5 3.3 5.3 0.1 44.8 48.3 2.0 0.0 0.6 2.5 0.4 0.6 0.1 0.1 0.0 0.4 0.0 18.5 3.7 0.0 6.3 0.0 5.3 1.9 0.1 0.6 3.1 0.3 2.9 0.0 0.0 13.2 0.2 0.6 4.4 0.0 4.8 17.7 0.0 0.0 0.5 0.3 0.0 10.1 1.2 6.1 0.3 0.0 0.0 0.0 3.2 0.0 1.0 0.0 0.2 0.0 6.0 31.6 0.0 1.1 0.0 0.0 0.8 1.2 0.9 13.2 0.3 0.0 0.1 0.2 0.0 0.2 3.7 1.7 13.7 2.6 0.1 1.4 0.5 MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Mental retardation, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 407.6;Hofbauer cells: 273.6;Inhibitory neurons: 378.7;Kupffer cells: 394.7;Proximal enterocytes: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Group enriched" "Detected in some" 13 "Karpas-707: 207.0;RPMI-8226: 355.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB010296: AB_638562, HPA028289: AB_10602024" "unprognostic (6.76e-2)" "unprognostic (1.74e-2)" "unprognostic (6.45e-2)" "unprognostic (7.65e-2)" "unprognostic (7.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (2.33e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (4.54e-2)" "unprognostic (7.83e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" 27.8 15.4 14.6 20.7 14.5 4.0 17.3 10.3 13.5 35.0 14.2 11.4 70.3 23.5 6.0 22.6 20.1 16.7 6.8 13.7 13.0 48.2 25.7 18.8 30.9 19.0 22.6 39.2 3.2 50.8 5.3 36.1 17.6 18.4 10.7 4.7 11.8 15.4 49.6 57.8 83.0 17.8 18.7 26.0 13.0 10.0 28.7 17.9 23.1 19.8 23.9 17.7 30.5 29.8 0.0 0.0 22.4 0.0 0.8 0.0 0.5 2.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.0 0.8 0.7 0.4 0.0 7.2 8.3 0.0 0.0 0.2 1.0 0.1 14.3 0.1 6.4 0.0 0.2 0.0 0.0 0.3 2.4 207.0 1.5 0.1 0.2 0.4 13.5 0.0 0.0 0.1 6.2 355.1 0.0 1.9 0.5 0.3 0.9 0.2 0.6 8.7 0.2 0.0 4.5 0.0 6.9 0.5 0.9 0.0 0.0 0.0 0.9 0.0 1.4 38.1 0.3 0.0 1.1 1.1 8.6 0.0 3.2 2.7 0.1 0.0 0.2 0.5 0.0 0.9 0.3 0.0 4.7 0.6 14.6 14.5 10.3 13.5 13.7 13.0 19.0 22.6 17.6 18.7 28.7 29.8 40.2 9.6 14.6 24.8 10.4 88.3 3.7 30.1 51.2 9.7 8.5 33.1 8.2 57.2 7.7 3.7 0.0 1.7 71.5 18.2 11.7 1.7 1.1 8.1 114.1 42.7 3.0 8.4 5.1 0.8 3.0 73.0 12.8 6.6 22.1 73.0 407.6 63.7 273.6 0.0 378.7 8.9 16.2 394.7 57.9 9.0 149.8 127.2 44.4 122.7 2.7 78.1 40.2 67.3 20.0 4.0 9.9 115.1 48.1 33.9 288.9 146.6 3.0 2.7 13.1 42.7 40.0 1.1 2.0 107.4 141.2 4.2 122.2 28.0 10.1 5.4 MAGEA11 "CT1.11, MAGE-11, MAGE11, MAGEA-11, MGC10511" ENSG00000185247 "MAGE family member A11" P43364 X 149688228-149717268 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "epididymis: 21.0" "Group enriched" "Detected in some" 5 "Spermatocytes: 29.4;Spermatogonia: 30.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-2 OS: 23.8" HPA052687 Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "HPA052687: AB_2681915" "unprognostic (4.06e-3)" "unprognostic (2.05e-1)" "unprognostic (7.21e-2)" "unprognostic (1.09e-2)" "unprognostic (9.64e-2)" "unprognostic (1.32e-1)" "unprognostic (6.13e-2)" "unprognostic (1.16e-1)" "unprognostic (6.67e-4)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 23.8 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 30.9 0.0 0.0 5.9 0.0 0.0 0.0 0.0 MAGED2 "11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386" ENSG00000102316 "MAGE family member D2" Q9UNF1 X 54807599-54816015 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Bartter syndrome, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Granulosa cells: 1684.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031572, HPA031573" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No 120000 "Cluster 44: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nucleoli, Cytosol" "HPA031572: AB_10599819, HPA031573: AB_10602181" "unprognostic (1.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.32e-1)" "unprognostic (1.69e-3)" "unprognostic (4.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.41e-3)" "unprognostic (1.39e-1)" "unprognostic (2.97e-1)" "prognostic favorable (2.88e-4)" "prognostic favorable (2.82e-4)" "unprognostic (6.34e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" "unprognostic (3.58e-1)" 81.6 125.1 102.3 52.8 97.8 31.8 162.6 104.9 112.2 174.5 111.7 106.8 54.3 134.3 101.9 67.4 149.0 94.3 142.2 95.5 121.9 141.0 57.5 85.9 48.0 125.4 118.4 255.9 75.5 148.0 195.3 177.1 128.8 208.8 53.5 74.4 103.3 169.9 88.9 60.5 62.5 140.6 108.5 60.8 77.6 63.1 110.1 68.8 149.2 91.4 46.2 111.7 95.7 108.9 34.0 61.4 373.7 111.0 171.6 229.5 66.8 137.9 243.7 106.4 187.5 62.3 84.4 47.1 361.2 279.0 88.5 45.2 106.5 104.2 76.1 84.5 87.0 100.0 68.6 122.1 145.5 25.4 71.8 310.4 43.0 109.3 55.5 223.6 209.9 55.2 24.5 55.7 207.6 94.0 57.0 41.9 134.7 59.1 72.4 37.4 132.9 68.2 148.5 25.3 56.6 149.5 54.7 62.4 330.6 437.5 263.1 42.9 185.0 90.4 141.3 135.9 39.5 35.7 32.7 34.5 132.0 66.7 477.6 178.5 31.9 132.1 119.1 80.0 91.7 59.2 98.1 112.1 41.1 63.9 97.3 112.0 11.8 108.6 140.8 25.8 108.9 127.4 102.3 97.8 104.9 112.2 95.5 121.9 125.4 118.4 128.8 108.5 110.1 108.9 77.9 44.8 42.8 17.6 37.4 42.4 96.4 198.6 43.3 69.8 123.3 97.8 60.5 44.3 175.4 77.3 29.2 231.5 36.9 11.9 246.5 107.4 3.4 42.4 96.8 116.4 58.3 10.3 12.9 53.7 133.7 151.7 20.9 57.1 102.1 1684.0 79.9 16.2 69.1 138.0 20.3 48.8 173.0 19.5 47.4 17.4 233.3 41.1 158.3 21.5 42.1 175.9 44.3 17.6 20.4 47.9 33.7 320.4 46.7 75.2 25.5 149.3 119.9 66.0 157.8 77.7 236.3 12.8 13.7 15.3 34.9 169.2 51.4 58.6 25.3 76.6 MAL "MVP17, VIP17" ENSG00000172005 "Mal, T cell differentiation protein" P21145 2 95025677-95053992 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2817.9;vagina: 863.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 373.3;Distal tubular cells: 236.7;Muller glia cells: 91.5;Oligodendrocytes: 168.1;Skeletal myocytes: 82.3;Squamous epithelial cells: 90.9" "Cancer enhanced" "Detected in many" "renal cancer: 101.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 217.6;naive CD4 T-cell: 293.3;naive CD8 T-cell: 138.1;T-reg: 233.6" "Lineage enriched" "Detected in many" 38 "T-cells: 293.3" "Cell line enhanced" "Detected in some" "HDLM-2: 516.4;MOLT-4: 722.0;RPMI-8226: 256.7;RPTEC TERT1: 2531.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065691 Approved "Golgi apparatus,Centrosome" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" Centrosome "HPA065691: AB_2685533" "unprognostic (1.57e-3)" "unprognostic (2.64e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (5.18e-6)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (5.13e-2)" "unprognostic (2.35e-2)" "unprognostic (1.06e-1)" "unprognostic (3.59e-1)" "unprognostic (4.61e-2)" "unprognostic (3.89e-2)" "prognostic favorable (3.96e-9)" "unprognostic (1.91e-1)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.57e-1)" 5.3 1.8 251.3 10.8 333.9 12.7 4.4 264.8 400.2 450.7 177.4 50.8 2.2 2.6 8.3 2817.9 8.9 2.9 17.9 260.8 256.7 400.4 1.7 25.3 25.1 281.3 282.1 3.2 3.0 0.4 3.9 3.4 272.9 21.8 6.3 10.1 544.0 11.1 2.8 12.6 17.0 2.4 264.0 9.4 52.7 1.1 303.2 261.2 21.3 4.3 352.8 15.0 863.2 449.3 51.3 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 12.0 0.0 0.3 2.4 0.2 0.0 0.5 516.4 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.4 2.4 0.4 0.1 0.1 0.0 722.0 0.2 0.2 0.0 0.0 0.7 0.0 256.7 2531.4 65.3 0.6 0.0 0.1 9.4 1.6 2.1 0.3 0.9 0.8 0.0 0.2 0.1 0.5 0.4 0.3 0.3 0.3 0.4 0.1 0.7 0.6 0.1 4.7 0.3 2.1 3.1 217.6 38.4 0.5 3.5 293.3 138.1 2.6 7.7 0.6 1.2 233.6 71.0 251.3 333.9 264.8 400.2 260.8 256.7 281.3 282.1 272.9 264.0 303.2 449.3 0.9 0.0 0.0 12.1 3.1 1.1 0.2 0.0 1.8 1.5 1.2 0.9 11.3 0.0 1.3 373.3 4.2 0.2 0.9 0.0 236.7 0.1 5.3 4.3 0.6 0.5 0.0 46.1 0.5 0.0 0.0 4.7 24.5 8.2 1.3 3.2 2.5 0.0 0.1 5.0 0.5 0.0 14.2 0.0 1.3 19.5 0.9 1.0 17.8 1.9 2.5 91.5 4.1 6.6 168.1 0.1 0.0 0.0 8.9 0.2 0.0 3.2 0.0 2.7 6.6 82.3 5.3 0.0 0.6 90.9 1.0 0.3 35.8 0.0 0.1 0.8 MALL BENE ENSG00000144063 "Mal, T cell differentiation protein like" Q13021 2 110083870-110116022 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 368.5;intestine: 235.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 857.8;Ductal cells: 299.2;Pancreatic endocrine cells: 354.9;Paneth cells: 374.4;Proximal enterocytes: 742.2;Urothelial cells: 426.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 8.4;neutrophil: 2.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "A-431: 267.4;A549: 269.9;CAPAN-2: 347.7;fHDF/TERT166: 380.9;HaCaT: 276.4;PC-3: 158.3" "Not detected" "Not detected" HPA051410 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA051410: AB_2681474" "unprognostic (5.17e-1)" "unprognostic (4.15e-2)" "unprognostic (2.92e-1)" "unprognostic (3.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (4.46e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (2.37e-1)" "unprognostic (7.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.84e-1)" "unprognostic (2.80e-1)" "unprognostic (6.50e-3)" 17.2 2.9 3.9 17.2 3.7 2.4 13.4 3.6 3.8 58.2 4.7 114.1 235.4 6.3 5.7 368.5 8.4 20.3 18.6 3.6 4.9 7.0 3.1 79.9 6.1 4.1 4.2 2.0 4.4 97.8 2.6 9.3 4.6 18.9 95.1 0.4 40.8 4.2 6.3 43.7 218.8 14.4 4.9 5.0 9.2 9.7 6.9 3.1 28.6 10.8 55.0 98.6 148.1 4.2 267.4 269.9 0.2 0.9 0.1 0.1 0.8 48.5 2.1 0.2 0.2 44.3 347.7 0.6 127.6 380.9 0.1 276.4 0.0 12.6 0.1 0.7 0.2 1.8 7.3 0.1 1.9 0.1 0.6 4.8 13.9 1.2 0.0 0.0 111.9 0.0 0.1 0.4 0.0 10.0 0.0 1.0 0.2 117.8 158.3 0.1 0.1 1.2 30.4 15.3 0.7 0.2 0.2 9.3 0.7 0.4 0.3 1.4 130.9 0.4 0.9 0.7 0.8 0.3 0.4 31.7 0.4 0.4 0.2 8.4 0.4 0.6 0.2 0.2 0.2 0.5 0.5 0.4 0.2 0.5 0.3 0.5 2.5 1.2 0.1 0.4 0.3 0.3 3.9 3.7 3.6 3.8 3.6 4.9 4.1 4.2 4.6 4.9 6.9 4.2 45.1 41.7 185.9 0.3 2.0 16.4 107.2 38.6 3.4 0.0 10.9 6.1 3.2 2.8 64.6 1.8 0.0 0.3 0.4 857.8 0.0 299.2 26.3 3.2 1.8 50.6 17.5 0.0 0.8 66.1 0.1 8.2 2.6 7.6 7.0 0.4 33.9 0.5 8.2 0.0 0.1 51.2 30.5 0.9 3.8 9.7 2.5 2.9 14.2 2.8 1.0 0.1 0.0 0.0 0.0 354.9 374.4 1.2 0.0 187.4 742.2 14.6 19.4 0.1 0.0 1.1 5.6 27.2 1.3 57.9 13.2 0.5 2.4 0.6 97.4 426.0 MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: AB_2680389" "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" 7.1 2.5 2.9 11.2 2.8 10.5 6.3 4.8 3.6 7.7 4.2 5.1 3.6 5.4 4.2 12.5 5.1 5.8 5.4 3.1 4.1 6.7 6.9 7.3 21.1 3.2 2.6 5.3 4.0 5.3 4.7 4.0 3.0 11.5 5.5 8.7 5.8 3.8 8.3 9.4 7.7 4.2 3.0 11.5 4.6 8.2 4.1 15.6 5.3 2.8 23.1 7.1 9.6 3.6 11.4 16.0 16.8 5.2 3.1 6.7 9.2 19.7 12.1 15.7 12.6 13.8 13.5 27.0 10.3 24.0 11.1 12.0 10.8 7.6 20.8 17.0 6.8 9.7 9.0 21.8 4.0 20.1 11.4 4.0 12.2 11.8 10.4 6.6 3.4 7.7 15.3 42.3 9.6 3.3 4.7 9.7 6.3 4.1 7.1 14.8 11.5 19.7 88.9 2.8 2.5 4.5 11.7 6.0 9.3 12.0 5.1 12.2 5.7 22.6 9.1 7.1 20.8 38.5 54.4 16.3 10.6 15.6 9.9 0.3 0.5 0.2 0.7 0.7 0.6 1.1 1.4 0.8 0.7 2.1 1.0 0.8 0.3 0.5 0.5 1.3 0.8 0.4 2.9 2.8 4.8 3.6 3.1 4.1 3.2 2.6 3.0 3.0 4.1 3.6 35.0 22.4 19.2 24.2 67.8 33.0 32.3 4.8 26.2 14.7 13.6 11.0 14.4 10.0 7.0 11.0 85.5 6.2 53.2 11.1 3.9 16.6 12.7 10.4 17.5 31.1 6.7 0.8 61.3 8.5 6.0 15.7 13.7 24.7 31.7 28.1 10.4 11.1 11.8 55.5 42.9 8.6 8.2 21.0 96.5 8.0 10.2 55.9 12.4 34.7 79.5 26.2 20.6 52.3 11.9 16.2 21.9 7.2 42.2 46.6 8.0 30.7 5.8 18.1 19.7 16.1 12.9 40.1 35.6 25.4 24.7 9.0 55.2 5.7 10.7 38.1 MAML3 "CAGH3, GDN, KIAA1816, MAM2, TNRC3" ENSG00000196782 "Mastermind like transcriptional coactivator 3" Q96JK9 4 139716753-140154184 "Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 125.6;Microglial cells: 355.1;Oligodendrocytes: 150.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 16.8" "Immune cell enhanced" "Detected in many" "basophil: 12.2" "Group enriched" "Detected in many" 5 "granulocytes: 12.2;NK-cells: 3.4" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 15.0;SCLC-21H: 15.7;SH-SY5Y: 23.9;WM-115: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037717 Approved Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA037717: AB_10794323" "unprognostic (1.83e-1)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (7.83e-3)" "unprognostic (4.73e-2)" "unprognostic (2.63e-1)" "unprognostic (3.36e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (3.89e-1)" "unprognostic (5.52e-3)" "unprognostic (1.73e-1)" "prognostic favorable (7.60e-5)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (7.22e-2)" "unprognostic (2.88e-1)" 3.3 3.4 1.5 2.4 0.9 3.2 3.4 16.8 2.1 5.0 0.1 3.8 4.8 6.7 5.3 5.9 5.5 4.1 2.0 2.2 2.8 2.0 2.6 3.8 2.6 3.4 2.3 8.6 6.8 3.3 4.5 5.0 3.4 4.9 3.9 1.7 5.9 4.5 1.7 7.8 4.5 6.0 2.4 3.3 3.4 3.0 2.2 6.0 4.3 2.1 2.3 3.6 5.1 2.2 0.5 8.1 5.4 2.7 2.1 4.4 4.9 1.0 4.4 0.5 0.3 3.2 2.2 1.8 0.4 0.8 0.3 0.1 2.1 1.8 0.3 0.0 1.2 5.9 1.9 0.3 0.4 2.8 8.7 4.3 1.5 0.1 0.9 3.3 15.0 0.1 1.6 0.0 0.3 0.9 0.5 1.2 1.4 3.6 3.5 3.5 0.5 3.6 2.5 11.2 15.7 23.9 0.0 4.2 5.5 4.2 2.3 0.8 13.1 0.6 1.3 0.1 1.7 2.9 3.5 0.1 0.8 9.2 20.2 12.2 1.5 2.9 0.0 1.1 0.1 0.0 0.0 0.0 1.5 0.4 0.4 0.4 3.6 3.4 0.9 1.2 0.0 1.2 1.5 0.9 16.8 2.1 2.2 2.8 3.4 2.3 3.4 2.4 2.2 2.2 21.2 3.2 11.5 39.5 3.1 8.0 8.1 4.2 7.4 4.6 12.6 9.3 3.0 11.5 8.7 5.5 18.8 5.8 3.9 13.6 5.9 5.1 3.6 12.6 9.4 11.7 14.9 9.4 60.2 5.1 7.3 5.3 8.6 19.9 19.6 34.4 13.2 17.5 7.5 11.8 125.6 12.1 2.0 22.6 13.3 9.0 4.1 19.6 3.6 355.1 18.3 3.1 1.0 7.5 150.8 3.0 14.0 3.8 2.1 5.7 8.2 6.1 7.2 3.7 0.0 2.9 13.7 0.5 2.2 19.0 13.5 8.2 5.3 8.5 11.0 8.9 MANEAL FLJ31434 ENSG00000185090 "Mannosidase endo-alpha like" Q5VSG8 1 37793847-37801137 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 16.5;Enteroendocrine cells: 30.5;Horizontal cells: 26.9;Inhibitory neurons: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063423 Approved "Golgi apparatus" "Intracellular and membrane" NA NA 47000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" "HPA063423: AB_2685011" "unprognostic (8.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (7.92e-2)" "prognostic favorable (5.28e-4)" "prognostic unfavorable (3.32e-4)" "unprognostic (3.02e-1)" "unprognostic (1.03e-2)" "unprognostic (7.67e-2)" "unprognostic (6.27e-3)" "unprognostic (1.08e-1)" "unprognostic (1.17e-3)" "unprognostic (8.29e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (2.26e-1)" 1.1 7.1 16.3 2.1 16.7 0.2 5.0 12.3 18.2 2.9 4.6 6.1 3.5 1.9 6.5 4.7 2.8 1.3 1.3 16.6 21.4 3.6 9.1 3.0 1.2 16.1 17.0 1.2 10.1 5.9 19.3 0.9 20.0 4.2 6.3 13.3 3.6 2.7 4.0 4.1 3.5 2.3 11.9 1.9 4.6 2.7 20.1 1.3 5.6 2.6 1.9 2.3 2.4 13.6 24.0 30.1 5.4 57.1 7.3 2.7 51.7 4.4 26.0 22.1 9.6 50.3 55.0 40.0 18.8 3.1 26.1 5.4 11.1 5.9 7.9 47.5 23.7 29.4 25.5 41.0 0.5 42.3 23.4 0.9 30.6 1.2 1.1 30.7 0.6 7.1 17.5 30.4 3.5 47.8 11.9 0.1 18.1 57.0 31.8 18.2 39.0 46.2 13.1 62.8 139.8 42.4 63.0 2.0 23.6 1.0 27.3 4.4 3.5 31.0 19.0 30.2 41.0 43.6 45.0 13.1 5.1 13.7 23.2 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 16.3 16.7 12.3 18.2 16.6 21.4 16.1 17.0 20.0 11.9 20.1 13.6 1.1 3.2 2.7 0.3 1.0 0.5 1.1 0.3 2.2 16.5 4.3 4.3 1.1 1.5 0.6 3.7 4.2 0.2 1.1 2.3 0.0 1.6 0.2 1.1 0.7 0.8 30.5 0.0 9.0 6.0 2.0 1.0 1.1 2.5 0.0 1.8 0.0 5.0 0.9 26.9 12.1 3.7 0.0 0.8 0.4 0.0 0.3 0.5 3.6 3.7 0.0 5.0 0.0 9.5 2.7 2.4 2.3 0.0 2.4 1.7 1.1 0.4 0.2 9.5 0.0 0.7 0.4 0.0 1.5 1.5 0.0 0.1 0.7 0.5 4.1 1.3 MAP1A MAP1L ENSG00000166963 "Microtubule associated protein 1A" P78559 15 43510958-43531620 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 325.5" "Cell type enhanced" "Detected in many" "dendritic cells: 90.9;Horizontal cells: 299.5;Peritubular cells: 76.3" "Cancer enhanced" "Detected in many" "glioma: 18.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 61 "plasmacytoid DC: 10.5" "Lineage enriched" "Detected in single" 61 "dendritic cells: 10.5" "Cell line enhanced" "Detected in many" "ASC diff: 60.7;BJ hTERT+: 61.8;fHDF/TERT166: 94.0;hTEC/SVTERT24-B: 58.1;U-87 MG: 121.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039063, HPA039064, HPA066488" Enhanced Approved Cytosol No No 55000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA039063: AB_2676327, HPA039064: AB_10673302, HPA066488: AB_2685676" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.86e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-2)" "unprognostic (5.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.65e-2)" "unprognostic (1.13e-3)" "unprognostic (8.36e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (6.59e-5)" "unprognostic (5.83e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (1.09e-5)" "prognostic unfavorable (1.66e-5)" 7.2 6.0 65.3 3.8 78.6 0.9 4.4 39.5 325.5 8.0 0.0 16.5 1.2 8.2 2.4 3.0 7.2 4.2 15.5 92.8 37.5 1.2 0.2 2.2 1.0 201.4 41.4 5.0 1.0 2.0 11.7 2.7 186.0 4.8 3.5 21.7 2.5 7.5 4.5 3.2 4.0 13.1 22.5 0.9 4.3 3.8 85.8 24.0 4.1 5.1 0.9 11.9 4.5 156.7 0.3 2.5 11.1 6.4 60.7 41.5 0.1 36.3 61.8 10.5 10.1 4.4 0.1 0.2 15.3 94.0 3.3 0.5 15.0 0.1 6.1 5.5 1.4 14.2 3.5 0.3 5.8 0.4 5.8 31.3 0.1 58.1 0.3 15.8 8.0 41.3 24.0 0.3 42.8 0.5 26.6 0.8 8.1 0.0 1.0 7.2 32.1 0.1 0.2 0.1 34.8 10.6 1.2 0.1 0.3 14.6 2.3 0.6 1.5 33.7 11.3 11.3 0.5 0.0 1.6 5.0 121.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.1 0.1 65.3 78.6 39.5 325.5 92.8 37.5 201.4 41.4 186.0 22.5 85.8 156.7 6.7 3.2 1.1 11.8 2.2 5.5 1.4 1.4 2.8 43.4 1.7 3.6 55.1 0.0 7.9 3.7 25.0 0.3 90.9 1.0 0.0 0.4 13.1 33.2 19.5 5.7 11.4 3.0 34.4 0.0 0.6 46.9 2.6 1.0 7.0 16.7 4.2 0.0 2.4 299.5 45.1 1.7 10.2 0.3 7.4 5.6 51.0 9.4 8.8 12.2 0.7 16.7 0.0 9.5 51.4 0.7 0.0 76.3 1.1 0.5 0.0 0.5 63.6 27.2 32.9 45.7 48.2 10.6 25.6 1.1 4.1 1.1 5.6 3.1 1.4 0.5 MAP2K6 "MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3" ENSG00000108984 "Mitogen-activated protein kinase kinase 6" P52564 17 69414697-69553865 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 40.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 53.9;Glandular and luminal cells: 82.7;Oligodendrocytes: 52.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 8.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 22.0;neutrophil: 45.9;plasmacytoid DC: 78.3" "Group enriched" "Detected in all" 9 "dendritic cells: 78.3;granulocytes: 45.9;monocytes: 22.0" "Cell line enhanced" "Detected in many" "A549: 40.0;AN3-CA: 21.4;HUVEC TERT2: 28.4;MOLT-4: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007744, HPA031134" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "CAB007744: AB_562318, HPA031134: AB_10603016" "prognostic favorable (2.27e-6)" "unprognostic (2.24e-1)" "unprognostic (8.46e-2)" "unprognostic (4.10e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.61e-3)" "unprognostic (9.52e-2)" "unprognostic (3.67e-1)" "unprognostic (4.09e-3)" "prognostic favorable (7.52e-4)" "unprognostic (3.61e-2)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (9.43e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-2)" 5.2 1.3 4.2 8.4 4.0 15.9 20.4 11.6 4.0 27.0 7.6 30.7 10.3 6.1 3.2 3.1 4.5 7.2 1.4 2.7 6.2 5.5 12.2 1.8 8.0 5.4 3.8 3.1 8.3 0.3 1.6 1.6 3.9 3.3 31.7 5.8 2.5 3.1 40.5 2.0 10.8 3.3 4.4 4.0 7.4 1.3 5.7 11.5 3.3 21.1 5.9 3.3 1.2 7.7 0.1 40.0 17.6 21.4 7.4 4.0 2.5 0.3 5.8 1.6 2.4 1.2 1.7 1.1 14.2 0.8 1.3 1.9 6.1 0.8 0.5 1.3 3.2 0.1 10.3 11.4 7.4 1.7 1.3 19.0 0.5 0.3 0.0 1.4 28.4 5.3 0.1 2.5 0.0 0.3 21.6 0.7 12.5 0.9 7.3 7.7 1.8 0.5 7.8 5.4 7.8 11.8 1.7 1.3 3.9 9.3 5.4 2.3 5.1 1.9 2.3 1.6 0.5 1.7 2.2 0.5 1.6 2.5 1.5 2.5 22.0 4.0 2.8 2.6 5.0 4.1 3.1 3.5 7.1 5.2 3.6 3.4 45.9 4.7 1.1 78.3 5.0 6.2 4.2 4.0 11.6 4.0 2.7 6.2 5.4 3.8 3.9 4.4 5.7 7.7 11.2 3.2 6.7 27.7 7.7 2.7 4.1 0.8 8.6 5.2 14.3 29.1 1.3 5.7 3.6 0.0 2.1 9.7 29.2 42.3 23.5 1.9 10.2 53.9 11.5 7.9 45.6 5.0 26.0 4.1 6.6 5.0 9.2 82.7 1.3 13.4 4.2 2.5 6.2 3.3 22.4 22.9 0.0 6.8 7.4 2.9 4.4 6.9 3.6 24.4 9.6 31.8 10.3 32.6 52.5 1.1 16.7 3.8 10.7 1.3 14.5 1.5 4.2 4.2 0.0 3.9 5.7 0.1 1.8 4.8 4.3 0.8 13.3 1.4 30.6 2.8 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815549-56896152 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 210.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 52.5;THP-1: 51.0" "Region enriched" "Detected in all" 6 "olfactory bulb: 18.2" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 57: B-cells - Immune response" Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 5.5 3.8 3.0 13.3 2.6 24.0 20.1 4.0 2.1 7.0 6.2 5.4 6.3 7.5 6.6 10.0 9.7 5.7 3.7 2.1 2.7 9.9 6.0 7.5 18.1 3.9 3.2 7.2 9.8 7.1 1.3 11.4 3.7 5.4 6.3 26.9 18.5 8.3 1.7 19.7 6.5 5.7 3.8 20.5 8.1 8.3 3.5 9.9 16.2 4.4 24.0 6.7 6.4 3.9 13.3 7.9 12.1 8.1 1.9 1.5 20.3 2.5 3.3 7.6 10.6 37.1 9.7 11.9 0.9 3.0 6.5 6.7 10.1 4.6 10.5 4.0 4.4 6.6 3.4 17.5 4.7 10.6 17.6 1.9 4.8 2.4 3.8 2.1 3.3 4.0 5.8 20.7 2.0 5.8 7.4 14.2 5.6 6.8 1.0 11.5 8.6 41.1 13.2 13.6 5.1 52.5 7.6 9.5 21.5 10.7 26.0 51.0 9.8 0.7 6.4 2.9 4.7 15.0 8.2 22.1 1.2 6.1 13.2 6.3 3.1 0.7 0.8 4.5 0.7 4.0 2.4 1.1 1.8 3.3 1.5 0.5 1.7 1.7 4.9 1.0 3.8 1.7 3.0 2.6 4.0 2.1 2.1 2.7 3.9 3.2 3.7 3.8 3.5 3.9 20.8 6.4 9.8 17.9 102.5 52.4 15.1 17.1 43.9 14.9 73.2 30.6 3.5 48.6 15.9 36.8 47.9 15.1 31.9 7.3 7.9 18.9 2.0 25.0 20.6 24.0 10.2 14.5 11.7 14.8 8.6 10.7 14.3 43.7 7.6 20.0 21.8 15.0 32.3 28.6 31.8 11.4 6.1 76.0 48.4 3.6 5.3 66.5 37.4 69.3 99.1 11.6 9.2 210.1 12.5 12.9 7.7 1.9 41.5 14.8 10.6 20.7 11.0 38.5 6.6 9.3 11.9 8.6 17.9 69.1 54.7 6.7 31.6 15.4 9.7 12.0 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21759657-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 341.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069, CAB079930, CAB079932, CAB079933" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nuclear speckles" "CAB004229: AB_627547, CAB079930: , CAB079932: , CAB079933: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 31.1 33.1 64.8 35.9 84.4 41.2 29.8 37.3 80.9 31.4 32.9 36.1 25.8 29.6 30.1 43.0 29.0 28.9 42.2 91.3 46.4 42.1 34.2 38.5 36.8 29.1 45.1 29.2 38.1 51.7 12.0 33.1 35.9 32.8 36.2 30.3 28.9 32.7 38.1 45.0 29.5 39.1 43.8 40.5 33.9 43.7 60.1 44.4 46.1 41.9 41.9 35.5 18.9 43.2 78.7 48.0 60.5 37.2 75.9 76.7 25.9 84.7 77.5 73.2 72.0 43.8 40.8 45.8 41.3 112.7 67.5 74.6 73.9 67.9 97.8 180.4 72.1 78.9 43.0 67.7 73.5 113.2 80.5 56.9 60.1 89.4 81.6 58.0 101.7 45.4 341.9 50.5 97.5 36.6 72.0 38.5 24.4 104.5 46.8 79.4 149.6 13.2 55.5 62.9 50.0 28.6 91.5 64.2 57.2 60.4 42.4 47.1 90.1 61.5 79.6 71.9 54.2 47.1 59.4 65.8 60.0 60.0 68.4 1.4 4.9 7.2 15.9 6.0 4.9 2.3 3.6 6.0 4.1 2.6 3.5 6.1 16.5 9.3 6.9 4.0 3.4 4.0 64.8 84.4 37.3 80.9 91.3 46.4 29.1 45.1 35.9 43.8 60.1 43.2 36.8 48.1 35.8 97.6 44.0 60.2 28.4 25.1 28.5 25.5 32.5 24.5 41.5 42.9 31.2 51.5 54.2 21.8 151.7 74.4 19.6 28.5 49.0 33.5 40.3 39.9 59.6 63.8 109.2 39.2 23.2 38.4 52.0 45.0 92.8 28.8 52.1 63.5 53.2 28.6 91.2 42.2 26.4 89.0 77.1 14.7 32.6 74.9 40.9 68.4 75.0 35.8 143.2 82.4 75.1 45.3 35.2 44.4 37.0 43.8 32.8 46.0 32.2 22.4 32.9 44.6 37.3 74.1 53.4 44.9 61.8 19.2 91.4 43.3 38.6 38.8 MAPK8IP1 "IB1, JIP-1, JIP1, PRKM8IP" ENSG00000121653 "Mitogen-activated protein kinase 8 interacting protein 1" Q9UQF2 11 45885651-45906465 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 166.8;pituitary gland: 118.2" "Cell type enhanced" "Detected in many" "Early spermatids: 43.8;Enteroendocrine cells: 40.2;Horizontal cells: 67.3;Late spermatids: 39.2;Muller glia cells: 41.3;Oligodendrocytes: 48.7" "Cancer enhanced" "Detected in all" "glioma: 51.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058921, HPA070332, HPA079657" Approved Enhanced "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA058921: AB_2683854, HPA070332: AB_2686254, HPA079657: " "unprognostic (3.96e-2)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (6.88e-2)" "unprognostic (5.59e-2)" "unprognostic (2.82e-1)" "unprognostic (8.25e-3)" "unprognostic (3.42e-3)" "unprognostic (1.27e-2)" "unprognostic (9.54e-2)" "unprognostic (3.22e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.23e-11)" "unprognostic (7.19e-2)" "unprognostic (4.01e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-3)" 4.8 23.3 127.9 2.3 131.0 1.3 4.8 122.0 147.7 8.2 29.6 8.3 1.4 10.9 3.5 2.2 11.3 3.5 5.5 166.8 120.6 11.5 5.6 4.0 0.6 154.9 130.9 9.1 43.1 19.2 118.2 1.4 142.6 11.6 1.2 11.5 11.4 6.1 2.4 4.0 3.7 5.7 124.6 2.3 9.0 27.7 139.3 1.0 7.0 2.5 0.4 6.7 4.8 164.4 0.0 7.1 9.4 26.2 3.4 1.8 0.3 5.1 4.6 9.9 7.2 6.3 1.1 0.4 2.5 5.9 16.8 5.8 10.2 4.8 4.4 4.0 13.1 0.1 8.6 4.1 3.1 0.6 4.4 2.4 1.0 6.4 1.3 6.6 2.2 0.9 11.5 1.6 2.8 3.9 0.4 0.6 24.9 3.3 10.5 0.6 15.4 0.3 4.6 0.2 76.4 28.5 8.4 6.8 10.0 3.6 11.0 0.4 2.1 12.5 19.1 19.0 9.3 1.1 1.3 0.5 7.9 0.2 3.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 127.9 131.0 122.0 147.7 166.8 120.6 154.9 130.9 142.6 124.6 139.3 164.4 1.7 6.4 4.1 7.2 0.9 2.4 5.8 2.0 2.8 34.4 6.1 5.3 1.1 5.7 3.3 11.0 22.9 1.6 0.4 2.2 13.7 6.9 43.8 23.9 15.9 2.9 40.2 0.0 10.3 28.9 0.6 6.5 4.1 19.9 0.0 2.8 0.4 4.6 0.5 67.3 11.6 1.6 4.1 0.8 3.5 39.2 6.2 1.1 3.6 1.0 1.6 41.3 0.0 3.5 48.7 11.6 0.5 6.4 0.1 6.3 1.4 8.9 10.9 18.3 0.0 14.2 6.0 10.6 8.2 0.9 1.0 5.7 1.3 7.7 0.9 5.5 MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 94.9;lung: 199.6;lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 6 "Kupffer cells: 1269.8" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Group enriched" "Detected in many" 4 "cerebral cortex: 4.1;thalamus: 12.6" "Group enriched" "Detected in some" 4 "classical monocyte: 33.7;intermediate monocyte: 56.5" "Lineage enriched" "Detected in many" 5 "monocytes: 56.5" "Cell line enhanced" "Detected in some" "HaCaT: 1.7;THP-1: 2.5;U-2 OS: 2.6;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" 64.7 31.1 0.4 87.9 1.4 3.4 7.4 0.7 4.1 0.7 4.4 5.7 2.0 0.7 1.3 2.4 25.5 2.4 19.0 0.9 1.0 1.6 94.9 199.6 17.7 1.2 1.7 7.5 0.8 0.3 1.5 2.8 1.9 1.8 2.1 0.0 4.4 2.3 1.5 2.5 3.1 29.8 1.2 37.1 3.5 2.0 12.6 1.3 1.5 5.0 1.1 25.2 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.6 0.4 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 33.7 0.0 0.0 56.5 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.7 0.0 7.2 1.0 0.0 9.2 0.4 1.4 0.7 4.1 0.9 1.0 1.2 1.7 1.9 1.2 12.6 0.7 0.7 25.6 45.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 3.4 1.8 0.4 1.5 16.7 3.7 0.0 0.7 1.4 0.1 0.0 3.9 0.0 0.0 0.0 5.2 0.0 8.0 0.0 0.2 1.1 2.6 0.0 0.0 12.6 0.0 11.4 3.4 169.6 0.0 0.0 0.0 0.0 1269.8 46.4 0.1 0.0 199.3 0.0 2.8 23.2 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.5 0.1 0.0 0.2 13.1 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.9 1.9 4.1 0.0 0.0 0.1 MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 150.1;Intestinal goblet cells: 68.2;Paneth cells: 102.9;Proximal enterocytes: 199.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 21.7;BEWO: 30.9;CACO-2: 23.6;CAPAN-2: 22.5;HaCaT: 21.4;MCF7: 40.8;RT4: 18.8;SK-BR-3: 18.5;T-47d: 26.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 17: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "Intermediate filaments" "HPA043514: AB_10959475, HPA045471: " "unprognostic (1.18e-1)" "unprognostic (3.92e-1)" "unprognostic (9.92e-2)" "unprognostic (5.56e-2)" "unprognostic (1.03e-1)" "unprognostic (6.16e-3)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (2.54e-1)" "unprognostic (8.75e-3)" "unprognostic (3.29e-1)" "unprognostic (5.16e-2)" "prognostic favorable (6.80e-10)" "unprognostic (2.63e-3)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "unprognostic (2.43e-1)" 0.2 0.3 0.5 3.1 0.6 0.6 6.2 1.8 0.9 4.0 6.5 23.6 31.1 1.8 7.3 4.2 4.2 4.8 0.3 1.1 0.5 12.9 5.3 2.4 0.5 0.4 0.5 0.5 17.1 12.5 1.0 5.7 0.5 6.0 18.7 2.1 11.6 2.5 0.8 3.3 33.1 0.6 0.1 0.4 2.8 0.9 0.5 0.9 3.9 0.0 1.7 3.8 2.5 0.9 21.7 0.7 0.5 0.9 0.0 0.1 30.9 0.0 0.0 0.0 0.0 23.6 22.5 0.2 2.3 0.0 0.1 21.4 1.9 10.3 0.1 0.0 12.1 0.0 0.4 6.2 0.0 0.1 0.2 0.9 12.5 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.0 40.8 0.2 0.3 3.5 13.4 0.2 0.0 0.1 8.8 0.3 18.8 3.7 0.2 0.4 18.5 0.0 2.4 26.3 0.3 0.0 0.0 0.4 0.4 0.2 0.2 0.3 0.1 0.2 0.2 0.2 1.8 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.4 0.2 0.2 1.2 0.4 0.1 0.3 0.2 0.1 0.5 0.6 1.8 0.9 1.1 0.5 0.4 0.5 0.5 0.1 0.5 0.9 0.3 9.6 8.4 0.3 0.8 7.9 28.7 9.6 22.8 7.0 25.4 10.7 0.6 40.0 17.9 9.2 0.0 36.5 1.5 150.1 1.9 29.8 4.4 14.2 1.5 1.0 61.5 0.0 0.6 33.7 2.5 1.5 6.1 19.4 0.0 3.8 0.4 9.1 3.1 0.0 0.6 68.2 14.2 1.0 1.0 3.3 0.3 1.2 0.0 0.0 0.8 1.0 0.0 0.0 0.6 26.3 102.9 0.7 0.0 38.4 199.3 27.6 17.4 19.6 0.0 4.1 1.6 9.6 5.0 19.6 3.7 4.8 1.4 0.0 61.3 44.3 MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 201.0;Peritubular cells: 258.8;Theca cells: 297.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Cell line enhanced" "Detected in many" "BJ: 72.5;BJ hTERT+ SV40 Large T+: 78.6;BJ hTERT+ SV40 Large T+ RasG12V: 106.7;HaCaT: 114.4;HBF TERT88: 100.6;SuSa: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" NA NA 1500000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" 54.4 51.0 24.3 30.2 22.5 1.8 43.6 17.6 23.2 194.4 19.3 67.5 58.5 147.0 101.6 32.8 46.9 40.1 110.2 20.0 23.4 39.3 24.6 15.2 18.0 24.1 30.5 116.4 11.3 28.0 9.9 177.9 26.3 104.9 57.8 45.7 42.6 171.9 4.0 62.8 80.6 98.1 18.3 5.9 23.7 31.2 23.4 4.9 271.4 28.5 15.4 103.0 139.2 30.8 24.1 10.8 23.3 2.5 60.7 3.6 15.0 72.5 17.6 78.6 106.7 13.0 8.4 0.1 7.0 29.2 3.5 114.4 2.3 4.4 100.6 0.0 2.9 0.8 6.1 0.9 14.0 0.0 0.0 13.6 9.5 16.1 0.8 22.1 0.5 1.3 0.1 0.2 4.1 11.2 0.0 0.7 7.1 0.3 3.7 0.0 2.4 11.4 5.7 5.3 16.0 1.5 11.5 0.2 19.8 67.3 10.9 1.4 0.6 5.2 31.5 16.1 11.0 0.9 0.2 0.2 18.8 0.4 5.9 0.0 0.1 0.1 0.2 0.4 5.2 0.0 0.7 0.9 0.8 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 24.3 22.5 17.6 23.2 20.0 23.4 24.1 30.5 26.3 18.3 23.4 30.8 27.8 3.2 1.3 11.1 0.3 37.3 10.1 6.2 80.2 6.3 3.8 45.8 29.1 18.6 3.0 16.5 54.2 1.2 0.2 20.6 0.0 9.9 86.0 4.2 22.6 32.4 23.4 3.2 6.4 0.0 1.1 113.1 5.1 5.0 0.0 43.5 201.0 11.0 1.6 0.0 11.5 25.4 0.0 5.0 7.7 108.6 103.5 0.9 28.4 19.7 2.0 8.1 0.0 86.0 59.8 3.2 18.2 258.8 0.0 6.5 118.7 3.4 1.6 52.9 13.1 97.2 17.1 2.5 2.6 7.3 8.5 2.5 2.0 297.5 27.4 1.8 MATN4 ENSG00000124159 "Matrilin 4" O95460 20 45293445-45308529 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "pancreas: 24.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Fibroblasts: 8.5;Langerhans cells: 6.3;Spermatogonia: 4.9;Suprabasal keratinocytes: 4.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 2.5;U-937: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 14000 "Cluster 25: Pancreas - Digestion" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.54e-1)" "unprognostic (2.39e-2)" "unprognostic (2.22e-2)" "unprognostic (3.60e-2)" "unprognostic (8.38e-2)" "unprognostic (9.67e-2)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (6.27e-2)" "unprognostic (6.74e-3)" "unprognostic (5.53e-1)" "unprognostic (6.19e-3)" "unprognostic (3.63e-6)" "unprognostic (2.38e-1)" "unprognostic (4.69e-2)" "unprognostic (4.27e-1)" "unprognostic (5.38e-2)" 0.7 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 24.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.4 0.0 3.2 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.1 0.1 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 6.4 0.7 1.0 0.0 0.0 1.6 1.9 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.1 0.7 0.2 0.4 0.0 0.0 1.0 2.5 0.0 8.5 1.1 0.8 0.0 0.3 0.4 0.2 0.1 0.0 0.4 0.1 0.0 0.0 6.3 0.5 0.0 0.1 1.8 1.0 0.0 0.0 0.0 3.0 0.4 0.9 0.1 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.4 0.4 1.6 4.9 0.3 4.3 0.3 0.3 0.1 0.2 1.0 MB PVALB ENSG00000198125 Myoglobin P02144 22 35606764-35637951 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Muscle protein" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 38 "heart muscle: 13154.5;skeletal muscle: 40709.4;tongue: 29085.2" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 5182.1" "Group enriched" "Detected in many" 7 "breast cancer: 13.6;head and neck cancer: 31.1;prostate cancer: 30.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 6 "NK-cells: 1.3" "Cell line enriched" "Detected in some" 4 "SK-BR-3: 175.6" "Low region specificity" "Detected in many" "CAB000060, HPA003123" Enhanced NA NA 13500000 140000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB000060: , HPA003123: AB_1079442" "unprognostic (7.51e-2)" "unprognostic (3.92e-3)" "unprognostic (1.07e-1)" "unprognostic (7.71e-2)" "unprognostic (2.35e-1)" "unprognostic (4.66e-3)" "unprognostic (5.78e-3)" "unprognostic (1.18e-1)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (2.74e-3)" "unprognostic (1.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.51e-2)" "unprognostic (2.35e-1)" "unprognostic (3.44e-3)" "unprognostic (1.19e-2)" 8.1 4.6 1.2 1.5 1.2 0.3 43.4 1.2 2.2 2.9 0.9 14.6 1.8 2.3 0.3 736.1 18.7 4.1 13154.5 1.0 1.9 2.8 5.8 14.9 5.3 1.4 1.4 5.3 26.9 16.1 10.6 3.1 1.2 214.2 12.9 0.2 367.1 0.5 40709.4 23.0 11.1 1.4 1.2 2.1 3.8 4.5 1.5 0.8 8.5 29085.2 1.8 1.3 4.5 1.0 1.9 7.6 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 4.6 0.7 0.1 0.3 1.0 0.8 0.2 0.0 0.0 5.4 0.3 0.1 0.5 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.5 0.5 0.0 19.2 0.1 0.6 0.0 1.9 2.3 0.9 0.5 8.0 0.0 6.4 1.5 0.2 19.0 175.6 0.0 0.3 39.4 0.1 0.4 0.5 1.2 2.2 0.2 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.2 1.0 1.9 1.4 1.4 1.2 1.2 1.5 1.0 0.3 0.0 0.0 0.3 0.1 0.3 4.3 12.5 0.0 0.0 30.7 23.9 5182.1 0.0 30.8 0.0 0.0 0.1 0.5 3.8 0.0 4.7 20.1 20.2 0.1 40.7 11.5 0.0 0.0 0.2 0.0 145.2 0.0 0.2 0.0 0.8 0.0 0.4 0.0 0.0 0.1 114.6 14.2 0.0 0.4 70.0 0.0 2.1 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.7 0.0 21.8 2.6 0.1 19.9 0.0 0.0 420.9 42.0 0.3 0.7 0.6 0.1 0.3 2.8 0.1 2.9 15.1 MB21D2 C3orf59 ENSG00000180611 "Mab-21 domain containing 2" Q8IYB1 3 192796815-192917856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.8;Inhibitory neurons: 53.0;Langerhans cells: 85.0;Oligodendrocyte precursor cells: 68.9;Syncytiotrophoblasts: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 4.2;T-reg: 3.9" "Lineage enriched" "Detected in single" 9 "T-cells: 4.2" "Cell line enhanced" "Detected in many" "HDLM-2: 114.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044026 Approved Approved Cytosol NA Yes "Cluster 13: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA044026: AB_10962840" "unprognostic (3.52e-2)" "unprognostic (1.02e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (3.74e-5)" "unprognostic (2.42e-2)" "prognostic unfavorable (9.94e-4)" "unprognostic (2.76e-2)" "unprognostic (3.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.46e-1)" "unprognostic (2.84e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-3)" "unprognostic (5.94e-3)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (3.28e-2)" 3.7 4.2 2.5 3.2 2.8 1.3 3.4 3.3 3.1 2.8 1.6 3.0 8.8 5.1 1.9 2.0 3.6 4.7 4.0 2.8 2.3 4.2 1.5 3.6 1.2 2.1 2.0 4.1 1.9 2.3 3.5 13.3 1.8 1.9 2.9 2.0 1.5 1.9 2.7 4.7 9.3 5.6 1.5 2.2 3.5 7.1 1.9 1.4 1.7 1.6 1.7 8.8 2.4 2.3 26.6 3.7 6.3 19.0 3.9 5.8 11.2 18.8 17.5 33.4 19.9 17.0 4.2 0.0 11.0 46.6 13.8 11.5 14.6 4.8 36.2 114.8 8.1 3.3 1.8 2.0 7.4 0.4 1.6 7.6 7.4 9.4 5.8 2.7 6.6 3.3 0.2 1.5 5.8 19.8 0.3 0.0 13.1 14.4 45.9 0.6 10.5 5.6 7.8 15.1 9.8 5.0 4.1 12.8 1.9 12.9 19.9 0.4 2.1 6.3 18.4 11.1 36.3 48.1 41.0 0.0 4.4 4.0 8.6 0.0 0.2 0.0 0.2 0.3 1.9 0.1 4.2 1.0 0.4 0.0 2.6 0.7 0.0 0.0 0.0 0.0 3.9 0.9 2.5 2.8 3.3 3.1 2.8 2.3 2.1 2.0 1.8 1.5 1.9 2.3 2.9 6.4 0.5 16.6 1.2 9.2 0.9 2.0 1.2 10.9 4.6 3.2 1.8 1.5 3.2 0.0 2.1 63.8 0.3 2.4 0.0 6.5 0.2 12.4 2.0 7.7 10.2 0.0 28.6 0.2 9.5 5.9 1.5 15.9 0.0 5.8 9.7 0.2 5.6 8.4 53.0 2.8 4.1 3.8 85.0 1.4 3.1 10.4 14.2 17.8 13.4 1.1 0.0 68.9 30.6 2.2 6.1 6.0 4.2 0.8 15.4 9.6 2.8 1.3 13.1 3.3 4.5 1.8 16.5 1.8 8.7 110.4 3.3 5.4 3.7 2.6 MBNL3 "CHCR, FLJ11316, MBLX39, MBXL" ENSG00000076770 "Muscleblind like splicing regulator 3" Q9NUK0 X 132369317-132489968 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 59.3;placenta: 170.8" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 328.3;Hepatocytes: 119.6;Syncytiotrophoblasts: 344.1" "Cancer enhanced" "Detected in all" "liver cancer: 13.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 123.8;Hep G2: 171.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001584 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Golgi apparatus" "HPA001584: AB_1079326" "unprognostic (3.38e-2)" "unprognostic (1.40e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.57e-4)" "unprognostic (1.87e-1)" "unprognostic (2.67e-3)" "unprognostic (8.74e-2)" "unprognostic (3.46e-2)" "unprognostic (2.19e-2)" "unprognostic (5.77e-3)" "unprognostic (4.36e-3)" "unprognostic (1.65e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" "unprognostic (2.43e-1)" "unprognostic (8.28e-2)" "unprognostic (2.37e-1)" 6.8 11.6 1.3 8.7 1.9 14.8 4.7 1.7 1.0 3.7 2.4 11.7 9.9 4.9 24.3 10.9 9.4 5.7 9.7 1.1 4.4 8.0 59.3 5.9 13.8 3.6 3.1 4.8 10.0 4.2 1.6 170.8 3.2 4.0 11.5 0.1 6.6 11.1 0.6 12.6 9.8 4.0 2.0 11.3 13.0 42.8 1.6 14.3 8.2 3.4 15.1 8.5 2.8 3.7 7.2 0.0 8.6 1.4 1.6 3.6 15.7 0.5 3.2 1.1 0.0 123.8 22.7 32.6 0.7 1.3 1.1 7.7 19.8 8.2 0.8 3.3 7.6 29.1 25.9 171.5 1.5 32.9 10.2 1.5 7.1 0.0 3.6 0.1 1.1 20.4 2.6 9.2 1.6 19.2 56.3 12.5 1.3 27.5 1.6 53.2 10.7 18.6 5.7 18.6 3.1 10.5 14.8 8.6 4.3 15.1 3.1 8.4 3.9 6.3 1.2 8.2 6.7 18.2 13.0 47.0 1.2 21.8 20.2 11.9 7.9 5.5 16.6 9.9 14.4 20.6 9.8 11.6 8.8 25.5 10.0 11.2 1.2 18.7 21.7 17.0 2.2 9.1 1.3 1.9 1.7 1.0 1.1 4.4 3.6 3.1 3.2 2.0 1.6 3.7 4.1 3.2 6.8 16.0 16.9 8.8 2.2 2.1 5.2 0.7 3.5 3.6 14.7 41.5 5.0 11.0 0.0 328.3 9.5 12.8 3.9 1.5 5.8 12.6 1.3 3.6 6.7 55.8 0.9 5.4 56.6 7.5 15.3 6.6 8.8 6.8 6.4 119.6 29.3 0.0 0.9 9.8 0.0 27.2 6.5 9.4 23.0 9.6 7.2 30.0 10.6 0.2 9.2 0.0 20.6 1.3 3.6 50.8 12.2 1.4 6.4 9.7 4.5 1.9 0.0 3.1 2.7 2.1 1.7 13.6 8.5 344.1 10.3 5.7 10.3 3.3 MCCC1 MCCA ENSG00000078070 "Methylcrotonoyl-CoA carboxylase 1" Q96RQ3 3 183015218-183116075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 153.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008310 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA008310: AB_1853620" "unprognostic (4.01e-2)" "unprognostic (1.83e-3)" "unprognostic (2.05e-2)" "unprognostic (2.59e-3)" "unprognostic (3.46e-2)" "unprognostic (4.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-3)" "unprognostic (2.57e-3)" "unprognostic (9.82e-2)" "unprognostic (9.74e-2)" "unprognostic (7.65e-2)" "prognostic favorable (3.68e-4)" "unprognostic (4.73e-1)" "unprognostic (2.21e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" 37.9 22.6 9.5 9.5 10.9 13.9 33.2 9.9 13.4 12.3 13.8 17.4 16.1 10.1 14.6 17.6 12.2 11.9 34.2 9.2 9.3 58.8 59.3 17.9 11.7 9.5 9.1 17.2 31.2 18.7 8.4 6.3 10.6 15.1 18.6 10.8 18.0 13.4 21.9 12.2 13.8 10.6 9.3 11.8 21.7 9.1 11.1 16.0 18.9 26.3 15.5 26.5 9.4 13.3 43.1 16.5 10.3 10.6 42.6 19.1 20.4 19.5 26.4 21.1 23.5 22.9 17.1 47.6 31.0 17.2 35.8 22.0 15.4 12.9 26.4 16.6 17.0 40.0 18.3 23.9 28.7 27.5 22.0 21.6 14.5 10.0 23.3 14.0 28.6 40.7 22.7 24.7 23.6 35.4 27.1 15.9 11.2 66.3 17.9 22.4 22.6 60.1 32.2 67.2 22.0 16.4 75.3 100.1 21.1 10.7 153.9 37.8 14.0 15.8 12.5 12.8 28.6 24.3 48.8 48.2 16.8 38.4 15.2 14.4 13.3 25.0 10.7 15.6 12.3 17.9 14.1 11.8 26.6 15.4 14.7 13.1 2.1 25.4 16.8 17.3 9.6 10.7 9.5 10.9 9.9 13.4 9.2 9.3 9.5 9.1 10.6 9.3 11.1 13.3 6.2 9.6 53.9 44.7 14.6 7.0 20.1 17.9 15.9 13.0 10.6 9.5 32.8 31.5 20.2 27.6 10.4 35.4 6.3 7.2 33.2 25.3 5.4 11.0 10.2 6.6 6.0 10.9 66.6 17.2 5.4 10.3 21.4 21.9 7.6 19.0 6.1 36.5 16.5 8.4 56.9 13.6 16.2 11.1 8.6 5.5 8.7 10.5 7.2 44.0 10.5 12.0 4.1 47.7 61.6 13.4 15.8 10.5 12.5 10.4 13.5 40.6 21.4 11.2 6.6 11.6 9.6 8.1 4.4 22.3 5.8 28.3 10.1 24.3 20.5 21.7 MCM10 "CNA43, DNA43, PRO2249" ENSG00000065328 "Minichromosome maintenance 10 replication initiation factor" Q7L590 10 13161558-13211110 "Predicted intracellular proteins" "DNA damage, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.2;lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.8;Erythroid cells: 23.5;Extravillous trophoblasts: 20.9;Plasma cells: 15.3;Spermatocytes: 15.8;Spermatogonia: 12.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045899, HPA071952" Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "HPA045899: AB_10960529, HPA071952: AB_2686477" "unprognostic (9.76e-3)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-3)" "unprognostic (1.41e-1)" "unprognostic (6.58e-3)" "unprognostic (1.78e-8)" "unprognostic (2.42e-3)" "unprognostic (3.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.78e-4)" "unprognostic (7.81e-2)" "unprognostic (0.00e+0)" "unprognostic (8.87e-2)" "unprognostic (1.29e-1)" "unprognostic (9.73e-2)" "unprognostic (1.05e-1)" 1.2 0.1 0.0 3.3 0.1 9.2 0.8 0.1 0.2 0.4 0.1 1.7 1.5 0.4 0.1 1.9 0.2 0.2 0.1 0.0 0.0 0.1 0.7 0.3 4.8 0.0 0.1 0.2 0.1 0.2 0.1 2.1 0.1 0.1 2.2 0.1 0.3 0.0 0.5 1.1 1.2 0.8 0.0 1.0 0.8 1.5 0.2 8.1 0.3 0.1 4.5 0.6 0.6 0.1 38.0 42.0 48.6 36.9 1.6 2.9 21.2 38.7 5.9 42.7 44.0 41.3 26.4 56.7 17.1 9.9 15.7 43.3 69.0 22.8 39.2 29.7 32.9 70.9 17.6 27.7 0.0 36.6 30.8 0.6 0.8 43.3 4.0 3.5 14.0 45.0 85.2 37.6 23.4 34.0 87.7 15.7 28.9 36.3 10.3 68.3 43.0 34.6 9.8 13.7 9.7 36.6 31.3 22.0 5.9 25.2 27.7 24.9 8.6 27.0 50.3 41.0 42.4 11.7 49.0 74.3 17.2 39.6 21.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.9 0.3 0.1 0.1 0.7 0.4 0.1 0.1 0.0 0.4 0.4 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 1.7 0.0 0.0 0.0 1.8 1.7 0.4 0.8 0.0 0.0 0.8 0.5 2.4 0.0 0.8 0.0 0.0 11.8 0.8 2.4 0.0 0.4 1.0 0.3 1.2 1.4 0.0 23.5 0.4 0.2 20.9 1.8 1.1 1.0 0.0 7.2 0.0 0.2 5.3 0.0 0.4 1.2 2.0 0.6 0.4 1.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.1 0.4 15.3 0.2 0.2 0.0 0.0 0.0 0.0 0.4 6.4 15.8 12.9 3.6 0.4 3.4 1.2 0.8 3.1 0.4 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.7;lymphoid tissue: 37.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.3;Erythroid cells: 65.6;Extravillous trophoblasts: 28.8;Spermatogonia: 25.9;Syncytiotrophoblasts: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 120000 "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 3.1 3.4 2.0 16.4 1.9 67.7 6.2 2.5 1.9 5.3 0.6 9.2 8.1 5.0 2.4 11.0 7.6 2.5 6.4 1.9 1.8 3.4 6.3 3.4 26.8 2.3 1.9 6.4 3.0 3.7 2.4 17.0 2.6 5.0 10.2 3.5 4.7 2.8 9.4 10.6 8.6 5.3 2.0 9.6 5.7 12.3 2.0 37.6 4.8 5.8 26.0 4.2 5.4 2.4 133.6 110.3 122.4 102.1 7.0 14.4 110.5 65.2 42.3 129.9 146.9 177.7 84.7 136.0 65.2 32.3 113.6 105.6 204.8 76.1 79.1 127.2 127.1 227.4 134.8 131.1 4.4 214.3 102.4 8.2 8.4 86.1 13.1 15.3 40.6 160.7 116.0 123.7 47.4 169.0 229.0 156.2 172.5 108.3 90.7 242.4 165.1 203.3 26.9 97.9 143.0 106.8 175.8 48.9 16.7 45.7 111.9 165.3 20.3 104.2 87.9 128.4 91.7 127.1 163.5 362.6 73.2 159.7 41.0 0.0 0.6 0.3 4.4 1.4 5.5 9.7 3.9 5.4 2.9 8.1 3.6 4.7 0.9 6.5 0.4 3.7 11.2 3.5 2.0 1.9 2.5 1.9 1.9 1.8 2.3 1.9 2.6 2.0 2.0 2.4 1.2 3.2 2.0 0.7 8.5 4.6 2.6 4.6 2.2 2.5 4.1 5.3 8.3 0.0 3.9 0.0 0.0 63.3 1.8 4.8 0.0 5.3 0.9 5.2 3.5 2.9 3.6 65.6 0.3 1.9 28.8 4.2 6.6 4.8 1.3 18.8 1.4 1.7 18.2 0.0 0.4 8.2 0.0 1.6 3.2 0.7 1.8 2.7 1.8 0.0 9.2 2.1 0.0 0.0 0.7 2.1 1.7 1.5 20.5 0.8 1.1 0.8 7.4 2.1 0.0 2.6 4.1 8.1 25.9 7.1 3.0 33.5 6.3 3.8 13.8 2.3 MCRIP2 "C16orf14, FAM195A, MGC15416" ENSG00000172366 "MAPK regulated corepressor interacting protein 2" Q9BUT9 16 636817-648474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 48.1;liver: 56.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 189.2;Distal tubular cells: 183.9;Hofbauer cells: 133.9;Proximal tubular cells: 310.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/84: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060363 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA060363: AB_2684263" "unprognostic (7.14e-2)" "unprognostic (3.85e-2)" "unprognostic (8.25e-2)" "unprognostic (2.49e-2)" "unprognostic (2.72e-1)" "unprognostic (4.18e-2)" "unprognostic (1.60e-1)" "unprognostic (2.96e-3)" "unprognostic (7.82e-2)" "unprognostic (3.14e-1)" "unprognostic (2.19e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.06e-2)" "unprognostic (4.00e-2)" "unprognostic (2.10e-2)" "prognostic favorable (7.23e-4)" 9.0 31.4 5.1 2.1 4.8 1.7 5.2 7.0 8.6 4.0 17.3 21.0 6.8 4.0 0.0 8.6 4.3 0.5 48.1 4.8 4.3 25.5 56.1 5.7 0.8 4.6 4.4 4.3 12.5 2.6 12.7 2.2 5.0 8.1 0.9 0.1 8.8 1.5 39.2 2.9 10.7 0.3 3.8 9.5 14.6 5.6 6.3 0.3 7.3 3.3 0.6 9.4 4.3 3.6 14.7 3.4 0.4 6.0 1.3 3.7 7.1 7.8 2.4 3.8 2.1 3.9 6.8 23.9 18.8 0.7 2.2 15.0 2.4 6.0 0.1 19.0 30.4 10.6 3.5 3.1 6.8 18.2 14.4 2.2 5.4 1.7 2.0 1.4 1.3 6.3 23.6 3.0 0.7 4.4 1.7 30.0 9.2 7.5 37.1 25.9 0.1 34.5 3.1 1.1 15.3 7.7 13.9 9.9 26.0 0.3 8.8 14.4 6.1 0.3 7.8 8.6 10.9 37.6 47.0 35.9 1.4 15.8 0.9 0.0 11.3 3.1 1.2 12.9 3.1 10.5 3.3 3.7 10.0 6.8 4.2 2.8 0.2 2.5 14.5 0.3 3.9 3.5 5.1 4.8 7.0 8.6 4.8 4.3 4.6 4.4 5.0 3.8 6.3 3.6 11.3 3.2 12.4 0.0 10.0 0.0 0.0 0.0 0.0 0.0 55.5 53.8 0.0 0.0 1.8 64.4 0.0 189.2 7.9 0.0 183.9 62.7 0.0 17.3 13.1 4.6 0.0 0.0 0.0 70.8 27.6 7.5 0.0 16.9 5.1 51.1 0.0 0.0 133.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 40.3 0.0 0.0 0.0 0.0 67.4 0.0 0.0 1.7 0.0 0.0 310.2 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 79.6 6.3 50.3 0.0 0.0 MCUR1 "C6orf79, CCDC90A, FLJ20958" ENSG00000050393 "Mitochondrial calcium uniporter regulator 1" Q96AQ8 6 13786557-13814568 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 81.6" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 238.5;Rod photoreceptor cells: 293.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078654 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA078654: " "unprognostic (1.82e-3)" "unprognostic (1.58e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-3)" "unprognostic (8.62e-2)" "unprognostic (2.25e-3)" "unprognostic (2.01e-3)" "unprognostic (2.16e-1)" "unprognostic (4.83e-2)" "prognostic favorable (5.51e-4)" "unprognostic (3.40e-1)" "unprognostic (5.77e-2)" "prognostic favorable (3.32e-4)" "unprognostic (5.86e-2)" "unprognostic (2.68e-1)" "unprognostic (4.05e-2)" "unprognostic (2.39e-1)" 9.7 5.4 20.2 7.2 21.0 7.1 10.0 19.6 32.6 7.8 18.5 10.8 19.1 7.0 13.1 10.0 4.6 5.5 12.2 20.9 21.3 22.6 9.2 8.6 6.6 21.0 20.8 3.9 12.6 9.0 5.9 8.7 22.0 6.4 9.7 81.6 9.1 7.6 19.3 18.3 16.5 5.1 20.0 7.6 6.4 4.8 22.5 8.1 16.0 15.8 9.4 6.2 7.7 19.7 23.4 6.9 34.4 34.6 19.8 17.0 21.8 21.0 19.9 22.4 23.4 24.0 11.3 31.6 41.0 15.1 35.2 10.2 21.5 17.7 25.4 21.2 13.1 32.3 12.2 24.0 19.4 32.4 12.6 11.9 16.9 29.1 20.9 16.7 8.1 38.7 24.4 16.3 15.8 9.7 40.1 49.0 22.2 59.9 9.0 29.2 30.3 45.2 27.4 14.2 22.0 24.9 14.0 35.4 58.1 53.1 13.2 14.6 11.5 33.5 18.8 24.2 29.3 20.0 71.9 45.4 15.6 19.0 46.4 4.2 1.3 0.3 1.5 1.2 1.8 1.9 2.1 2.2 3.2 1.7 1.6 1.5 0.8 1.7 1.7 2.0 1.3 2.9 20.2 21.0 19.6 32.6 20.9 21.3 21.0 20.8 22.0 20.0 22.5 19.7 40.5 16.0 25.0 13.1 33.2 44.7 24.2 16.9 39.3 48.0 62.8 54.1 43.6 28.6 15.1 57.0 120.9 45.3 27.2 75.0 138.9 27.4 48.9 29.3 83.5 38.7 15.6 62.9 16.7 31.7 66.9 30.5 7.1 31.3 7.0 16.7 28.2 72.4 91.6 26.9 11.5 49.6 24.4 34.7 80.2 6.8 22.1 60.1 51.6 10.3 36.6 50.4 25.7 7.5 13.4 29.2 91.3 27.1 80.7 60.2 161.6 238.5 11.2 293.7 19.7 20.7 34.5 13.1 52.4 47.3 57.4 86.2 21.0 31.0 37.5 31.1 MEF2A "RSRFC4, RSRFC9" ENSG00000068305 "Myocyte enhancer factor 2A" Q02078 15 99565417-99716466 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 262.8;Microglial cells: 708.3;Oligodendrocytes: 264.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004499, HPA046597" Approved Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004499: AB_627921, HPA046597: AB_2679714" "unprognostic (1.89e-1)" "unprognostic (8.82e-2)" "unprognostic (5.91e-2)" "unprognostic (8.04e-2)" "unprognostic (8.68e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.93e-2)" "unprognostic (1.91e-2)" "unprognostic (7.08e-3)" "unprognostic (1.46e-1)" "prognostic favorable (6.93e-4)" "prognostic unfavorable (7.96e-4)" "unprognostic (4.69e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-3)" 32.8 22.9 18.7 20.3 25.4 18.3 22.1 16.4 27.6 27.7 12.9 23.5 12.8 34.5 23.8 21.7 21.8 22.6 89.7 21.9 12.1 24.8 24.5 30.4 25.0 17.4 20.7 30.1 12.8 37.6 9.8 26.4 15.4 23.0 15.0 24.2 19.5 23.7 61.5 54.8 17.6 35.7 18.4 27.2 17.8 15.0 28.4 23.3 19.7 81.9 22.9 22.5 16.6 25.7 17.9 10.1 16.7 8.5 20.7 26.3 8.2 17.8 40.8 14.4 19.5 10.4 24.4 22.3 24.5 38.6 22.1 19.3 17.1 14.1 18.6 15.3 24.8 45.2 22.3 9.4 35.4 18.1 21.3 17.6 23.2 19.3 39.7 59.6 26.5 18.3 16.3 41.6 27.0 7.4 29.7 26.3 8.9 11.9 14.6 43.3 36.1 18.5 29.5 24.9 10.7 14.8 27.2 11.6 51.0 17.6 11.0 16.4 43.7 39.8 21.9 19.9 21.7 22.6 27.8 48.5 27.8 19.6 38.7 7.7 12.1 14.3 3.9 15.6 3.3 15.8 3.6 3.6 13.3 12.1 5.0 3.9 10.8 6.5 19.3 7.8 2.6 5.6 18.7 25.4 16.4 27.6 21.9 12.1 17.4 20.7 15.4 18.4 28.4 25.7 152.7 80.1 43.9 113.9 87.2 88.6 31.7 26.9 62.0 52.0 31.6 37.0 175.8 20.0 40.7 29.5 50.1 7.7 32.9 26.5 25.4 18.0 10.4 80.3 60.6 100.6 12.7 24.8 262.8 18.8 3.4 61.5 34.7 130.7 31.0 30.5 50.3 41.0 39.5 30.3 174.9 17.2 12.2 107.5 63.1 7.8 55.9 104.1 35.6 708.3 65.8 25.2 23.7 157.3 264.4 26.8 22.6 64.7 55.6 27.0 18.9 19.7 51.7 44.9 72.3 62.4 69.4 29.9 29.6 29.4 50.4 9.2 27.8 28.8 17.9 26.8 MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 471.5;Excitatory neurons: 735.7;Inhibitory neurons: 759.5;Microglial cells: 730.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Cell line enhanced" "Detected in many" "Daudi: 103.6;HEL: 229.3;Karpas-707: 121.6;REH: 261.8;WM-115: 145.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" 28.9 26.8 29.7 39.2 58.6 11.1 17.5 0.0 75.3 18.8 0.0 15.9 6.9 25.9 7.3 13.6 17.3 28.5 35.2 55.7 0.0 10.4 10.5 21.3 62.9 0.0 0.0 34.9 5.6 9.3 6.3 45.5 0.0 20.0 15.4 34.2 9.0 17.7 555.4 4.9 11.2 31.5 0.0 43.8 12.7 9.4 0.0 12.8 21.7 246.8 77.7 21.3 7.6 11.0 1.6 0.0 7.1 0.0 7.7 4.6 0.2 2.2 4.5 0.3 1.0 0.2 1.0 103.6 0.6 12.0 2.5 3.1 9.6 9.1 0.2 31.7 12.5 229.3 12.3 0.0 2.8 10.4 0.6 21.6 0.0 0.3 0.0 1.4 35.1 0.0 12.3 121.6 9.0 0.0 0.3 0.1 2.2 0.1 8.4 261.8 63.1 50.5 0.0 1.2 0.0 8.3 0.0 0.7 29.5 3.9 0.3 58.0 40.4 5.6 1.0 0.6 5.4 92.0 11.5 62.0 1.5 70.1 145.2 0.6 72.0 0.2 0.2 82.6 0.1 141.6 0.2 0.1 95.2 187.9 0.2 0.2 24.3 16.7 71.5 100.3 0.5 34.4 29.7 58.6 0.0 75.3 55.7 0.0 0.0 0.0 0.0 0.0 0.0 11.0 367.4 32.1 52.0 117.5 471.5 10.7 4.2 0.0 7.4 22.6 5.2 26.5 86.4 10.0 21.7 1.8 214.8 0.8 138.6 9.2 27.4 0.8 11.0 0.8 13.4 197.5 1.2 59.1 735.7 12.7 1.2 26.8 2.0 1.0 5.1 107.5 283.4 3.4 171.1 5.0 759.5 1.5 0.0 205.8 127.5 8.6 29.8 205.1 67.6 730.7 202.7 61.8 8.2 119.6 18.7 0.4 3.0 71.8 314.7 2.1 0.2 0.8 3.7 202.9 335.2 72.7 257.6 4.0 29.5 2.5 8.4 1.6 12.2 58.6 6.3 2.3 MEFV "FMF, MEF, TRIM20" ENSG00000103313 "MEFV innate immuity regulator, pyrin" O15553 16 3242027-3256633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" Actin-binding "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 7.6;Kupffer cells: 15.1;Macrophages: 15.5;monocytes: 26.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 8.3" "Group enriched" "Detected in many" 4 "granulocytes: 8.3;monocytes: 5.7" "Cell line enriched" "Detected in some" 6 "THP-1: 6.6" "Not detected" "Not detected" HPA077497 Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA077497: " "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (4.96e-2)" "unprognostic (2.01e-1)" "unprognostic (2.49e-2)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "unprognostic (3.35e-2)" "unprognostic (2.97e-2)" "unprognostic (1.09e-1)" "unprognostic (8.89e-2)" "unprognostic (3.27e-1)" "unprognostic (7.58e-7)" "unprognostic (1.08e-1)" "unprognostic (7.16e-4)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" 2.4 0.6 0.1 6.5 0.2 6.1 0.3 0.4 1.0 0.2 0.3 0.4 0.5 0.2 0.2 0.3 0.6 1.0 0.5 0.3 0.1 0.4 0.7 4.0 0.4 0.3 0.2 0.1 0.2 0.0 0.2 0.8 0.5 0.2 0.3 0.2 0.3 0.0 0.7 0.2 0.6 1.0 0.0 8.9 0.4 1.3 0.3 0.4 0.3 0.3 0.3 1.8 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 1.1 0.0 2.4 3.2 0.1 0.0 3.4 0.0 0.1 0.1 0.0 1.7 0.2 0.0 0.1 8.3 0.3 5.7 0.1 0.0 1.2 0.1 0.2 0.4 1.0 0.3 0.1 0.3 0.2 0.5 0.0 0.3 0.4 0.2 0.0 1.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 7.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.4 0.2 1.0 0.0 0.1 0.0 0.0 15.1 2.4 0.3 0.0 15.5 0.0 0.0 26.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.2 0.3 0.7 0.0 0.1 0.0 0.6 0.0 0.0 0.1 MEI4 ENSG00000269964 "Meiotic double-stranded break formation protein 4" A8MW99 6 77650274-77927028 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 4.0;testis: 3.7;thyroid gland: 2.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 86.1" "Cancer enhanced" "Detected in some" "renal cancer: 0.9;testis cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 43: Testis - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.47e-1)" "unprognostic (9.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (1.88e-1)" "unprognostic (4.62e-2)" "unprognostic (9.70e-4)" "unprognostic (3.16e-1)" "unprognostic (2.86e-4)" "unprognostic (3.35e-2)" "unprognostic (4.17e-2)" "unprognostic (4.85e-2)" 0.1 0.7 0.4 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.2 0.6 4.0 0.8 0.0 0.0 1.0 0.5 0.0 2.0 0.1 1.0 0.0 1.2 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 3.7 0.6 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.2 0.2 0.6 1.0 0.5 1.2 0.5 0.6 0.6 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 86.1 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 21.3 0.3 0.0 0.0 9.4 0.0 0.6 0.0 2.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MFAP1 AMP ENSG00000140259 "Microfibril associated protein 1" P55081 15 43804492-43824690 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015583, HPA042370" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Centrosome "HPA015583: , HPA042370: AB_10796904" "unprognostic (1.05e-1)" "unprognostic (5.94e-2)" "unprognostic (2.56e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (5.28e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.08e-1)" "unprognostic (1.48e-1)" "unprognostic (1.66e-2)" "unprognostic (3.12e-1)" "unprognostic (7.02e-2)" "prognostic favorable (1.04e-9)" "unprognostic (1.66e-2)" "unprognostic (9.68e-2)" "unprognostic (3.82e-3)" "unprognostic (1.54e-2)" 15.9 24.0 17.5 17.6 18.0 12.9 21.4 21.3 23.2 16.6 19.7 17.1 14.5 18.8 23.4 22.2 18.4 14.9 22.1 17.7 19.3 23.7 18.1 15.2 26.6 18.3 19.3 24.8 15.3 33.2 14.5 23.2 18.7 22.8 18.1 25.0 17.0 17.7 26.3 20.5 15.0 19.1 17.7 17.1 16.8 19.3 18.5 24.4 24.7 23.2 32.4 20.6 17.5 19.1 40.1 41.0 69.4 46.0 57.9 36.3 42.7 63.1 43.8 50.3 58.2 64.1 25.6 42.8 58.7 39.4 50.9 70.8 62.5 51.7 58.9 72.9 37.6 103.7 71.6 48.5 45.4 62.3 53.2 34.1 55.3 48.0 43.3 48.0 49.8 48.3 95.8 35.7 60.9 30.0 51.1 47.0 49.2 74.2 35.4 73.9 69.6 27.6 52.0 59.0 43.8 43.0 55.6 47.0 27.0 55.2 70.7 39.5 47.4 50.6 35.8 56.3 51.7 43.5 112.2 91.8 42.5 58.4 37.9 42.5 25.5 56.9 35.3 34.8 34.7 35.0 35.1 33.6 32.6 28.3 35.7 35.0 22.6 50.5 29.1 26.8 44.1 26.3 17.5 18.0 21.3 23.2 17.7 19.3 18.3 19.3 18.7 17.7 18.5 19.1 30.4 35.3 30.2 5.2 32.8 30.3 59.6 50.1 35.9 41.8 22.4 28.8 31.0 25.8 43.2 51.5 6.2 94.6 33.2 27.4 56.7 44.2 6.2 43.1 39.9 35.6 11.3 32.0 9.0 29.4 55.0 29.8 21.4 39.4 46.3 37.6 20.7 18.8 35.4 32.0 8.6 24.4 38.7 20.7 20.5 6.3 28.0 25.5 26.6 5.6 30.6 51.5 33.0 2.0 8.2 26.8 27.1 35.7 20.6 39.3 22.1 42.9 60.0 35.2 19.7 35.9 41.7 49.7 84.8 28.1 27.7 147.4 33.6 39.4 21.3 50.6 MFAP5 "MAGP2, MP25" ENSG00000197614 "Microfibril associated protein 5" Q13361 12 8637346-8662888 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 242.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.5;Extravillous trophoblasts: 1015.1;Fibroblasts: 579.7;Syncytiotrophoblasts: 252.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 31.7" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 172.2;BJ: 63.7;EFO-21: 150.4;HeLa: 55.9;SuSa: 137.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 42.6" HPA010553 Enhanced "Secreted to extracellular matrix" NA NA 3200000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA010553: AB_1853843" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (4.25e-2)" "unprognostic (4.84e-2)" "unprognostic (1.44e-1)" "unprognostic (6.05e-2)" "unprognostic (2.15e-3)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (8.79e-2)" "unprognostic (8.63e-3)" "unprognostic (3.05e-1)" "unprognostic (4.41e-7)" "prognostic unfavorable (6.87e-4)" "unprognostic (8.81e-2)" "unprognostic (2.05e-2)" "prognostic unfavorable (5.81e-4)" 141.7 10.9 3.5 5.4 5.0 3.5 79.7 31.7 9.2 59.9 1.8 37.8 7.2 242.1 11.1 35.0 25.8 28.2 54.4 4.8 0.8 3.1 12.7 8.7 4.8 2.9 0.4 2.4 5.5 2.4 3.7 94.5 1.9 6.4 42.0 7.9 17.2 49.7 28.5 38.7 19.0 142.1 0.0 1.9 23.6 6.9 1.7 3.2 14.4 118.1 3.4 43.1 60.7 6.6 1.4 5.7 1.6 2.6 29.4 12.4 172.2 63.7 1.2 0.8 1.1 2.3 1.0 0.6 150.4 19.8 1.6 9.1 0.6 13.1 0.0 0.5 0.4 1.6 55.9 1.9 0.4 1.3 0.6 8.7 4.4 7.3 0.0 3.3 0.0 2.0 2.7 3.7 52.7 0.8 1.9 0.8 3.2 0.9 2.9 1.2 1.3 6.5 6.5 2.6 0.7 0.9 1.9 0.7 1.0 137.1 24.0 0.8 2.3 10.7 21.5 45.7 3.0 2.1 1.9 2.3 6.0 0.7 0.1 2.9 0.8 0.7 0.2 0.7 0.4 0.1 0.1 0.1 0.4 0.3 0.4 0.1 1.1 0.2 0.5 0.3 0.0 0.3 3.5 5.0 31.7 9.2 4.8 0.8 2.9 0.4 1.9 0.0 1.7 6.6 61.5 12.8 5.8 0.3 0.5 23.1 0.4 1.8 0.6 0.2 0.6 0.9 7.0 0.0 2.0 0.0 0.0 140.5 0.5 0.0 0.0 0.5 0.3 5.1 3.9 20.1 0.0 0.0 0.2 0.0 1015.1 579.7 3.6 28.0 0.0 0.2 4.2 0.0 27.7 0.0 0.1 0.0 0.0 9.5 36.3 0.5 61.2 8.8 12.4 0.0 0.1 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.6 0.1 0.0 0.2 1.6 0.9 0.0 40.2 35.2 0.1 0.2 0.6 18.0 252.3 5.3 0.1 0.0 0.3 MFSD6 FLJ20160 ENSG00000151690 "Major facilitator superfamily domain containing 6" Q6ZSS7 2 190408355-190509205 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 110.6;Respiratory ciliated cells: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 79.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022274 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA022274: AB_2142776" "unprognostic (9.47e-2)" "unprognostic (7.01e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-2)" "unprognostic (2.49e-1)" "unprognostic (4.13e-3)" "unprognostic (1.78e-2)" "unprognostic (3.08e-2)" "unprognostic (3.92e-1)" "unprognostic (3.77e-1)" "unprognostic (9.54e-2)" "unprognostic (2.08e-1)" "prognostic favorable (1.05e-4)" "unprognostic (3.46e-2)" "unprognostic (3.27e-1)" "unprognostic (9.14e-2)" "unprognostic (9.18e-2)" 20.8 40.3 29.1 12.7 31.7 7.6 21.3 37.0 40.3 21.8 0.0 31.8 19.8 10.5 32.8 40.6 19.5 15.8 17.9 35.5 27.6 10.8 2.3 26.4 14.8 45.8 48.3 4.1 16.8 64.5 35.4 8.6 52.4 23.0 28.9 14.9 30.8 32.3 6.4 29.8 24.6 14.4 28.6 20.9 32.1 7.9 38.3 19.9 38.9 14.2 20.6 22.9 21.5 51.2 25.1 15.2 0.5 5.2 10.6 13.6 20.4 12.7 25.3 8.4 10.5 5.6 31.1 39.1 5.8 26.4 15.6 41.5 7.4 22.1 9.5 79.7 11.6 20.9 14.2 2.9 4.2 8.3 6.4 2.1 39.3 12.5 8.1 27.1 3.0 30.5 5.4 42.2 2.2 9.7 38.8 1.8 3.4 27.1 16.1 8.6 1.2 34.1 15.9 45.1 47.5 12.2 17.9 41.7 24.9 1.7 13.6 9.5 12.6 1.4 2.9 16.6 19.7 19.3 8.6 13.8 13.5 16.9 6.9 4.6 1.1 0.4 1.4 0.3 1.5 1.6 1.8 2.0 1.5 0.7 0.9 1.9 0.1 2.1 0.5 0.7 3.5 0.8 29.1 31.7 37.0 40.3 35.5 27.6 45.8 48.3 52.4 28.6 38.3 51.2 48.6 32.1 20.0 7.2 7.6 6.4 11.5 11.7 10.8 9.7 16.8 9.8 21.4 5.7 30.3 23.9 8.4 0.2 14.9 25.1 0.0 13.2 46.8 27.9 5.9 26.7 35.4 7.8 55.7 20.5 0.2 8.9 31.1 22.5 24.0 8.7 16.1 0.8 4.0 28.6 47.9 42.7 12.2 4.0 8.0 13.7 5.6 12.3 8.8 11.2 9.7 6.8 3.1 41.7 110.6 24.9 20.8 5.3 14.9 13.5 13.6 1.0 88.5 7.9 0.0 16.7 7.2 1.0 1.4 28.8 18.3 0.0 17.0 18.6 21.1 22.7 MGAM2 ENSG00000257743 "Maltase-glucoamylase 2 (putative)" Q2M2H8 7 142111749-142222324 "Enzymes, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 11.8;pancreas: 4.0;salivary gland: 5.9" "Group enriched" "Detected in some" 4 "Early spermatids: 27.4;Late spermatids: 18.2" "Group enriched" "Detected in some" 11 "colorectal cancer: 3.5;pancreatic cancer: 2.5;stomach cancer: 9.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "OE19: 1.6;RH-30: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA055697 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" Vesicles Cytosol "HPA055697: AB_2682890" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-3)" "unprognostic (5.65e-2)" "unprognostic (2.19e-2)" "unprognostic (1.89e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-2)" "unprognostic (5.93e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-1)" "unprognostic (5.50e-4)" "unprognostic (7.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.71e-2)" "unprognostic (9.33e-2)" 0.1 0.0 0.0 0.4 0.0 0.2 1.1 0.0 0.4 0.0 0.2 1.5 11.8 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 5.9 0.0 0.0 0.0 9.6 0.0 0.0 0.9 0.5 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 27.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 MGAT1 "GLCNAC-TI, GLYT1, GNT-1, GnTI, MGAT" ENSG00000131446 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase" P26572 5 180784780-180815652 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 280.2;Syncytiotrophoblasts: 384.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017432 Approved NA NA 12000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA017432: AB_1853851" "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (3.38e-2)" "unprognostic (2.11e-1)" "unprognostic (3.91e-2)" "unprognostic (6.70e-2)" "unprognostic (4.39e-2)" "unprognostic (9.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.98e-1)" "unprognostic (3.70e-3)" "unprognostic (6.44e-2)" "prognostic unfavorable (8.65e-4)" "unprognostic (4.15e-2)" "unprognostic (3.52e-2)" "unprognostic (5.68e-2)" "unprognostic (5.00e-2)" 130.4 66.7 44.0 65.8 43.8 60.6 113.7 40.7 59.9 70.7 64.6 69.8 50.2 75.2 28.2 103.2 85.8 39.9 103.2 38.4 42.0 63.3 146.9 113.3 68.5 56.7 43.2 75.1 115.3 20.3 61.7 67.3 54.0 75.5 30.1 29.2 82.0 37.1 61.1 73.4 82.2 40.9 47.4 139.9 78.1 36.4 64.9 38.3 96.1 35.6 42.2 85.0 72.3 49.3 58.3 58.2 30.9 66.3 149.6 68.7 111.0 130.1 154.4 77.4 96.7 79.4 45.6 50.2 77.3 122.3 78.2 68.8 17.0 190.8 46.1 271.6 47.6 44.2 34.1 61.7 72.8 40.6 137.6 79.7 91.5 63.1 62.9 53.6 67.9 34.2 26.1 84.7 70.9 78.3 38.9 55.2 29.6 37.5 72.0 46.2 44.5 66.8 30.9 67.3 27.2 32.1 54.6 56.5 115.7 27.2 43.8 68.5 72.9 94.7 44.7 42.7 61.1 165.9 149.2 44.7 77.6 78.9 49.8 93.0 228.6 104.6 83.5 186.7 91.6 48.3 60.2 70.3 161.7 42.0 51.4 59.1 152.2 70.4 149.4 152.9 75.3 235.1 44.0 43.8 40.7 59.9 38.4 42.0 56.7 43.2 54.0 47.4 64.9 49.3 157.8 48.1 31.1 9.8 57.7 61.2 44.6 52.8 50.1 20.7 41.5 29.7 18.4 44.3 32.7 29.5 56.3 94.9 114.7 43.8 37.2 49.0 31.7 26.2 34.2 94.2 49.8 47.6 7.5 79.0 280.2 80.5 33.6 48.7 30.4 27.2 125.7 88.1 200.5 63.9 8.5 54.9 20.3 195.5 142.1 43.2 62.7 234.9 81.8 26.2 112.1 18.9 87.6 8.0 14.6 54.0 34.7 76.0 169.7 76.9 57.2 22.5 20.4 78.8 32.9 72.1 51.5 26.8 22.5 46.8 63.9 384.9 59.3 43.7 36.7 56.8 MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 441.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 194.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 276.3;OE19: 558.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010690, HPA010707" Enhanced Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Endoplasmic reticulum" "HPA010690: , HPA010707: AB_1853922" "unprognostic (9.35e-2)" "unprognostic (6.13e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (4.38e-2)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (6.41e-2)" "prognostic favorable (3.22e-9)" "unprognostic (4.10e-1)" "unprognostic (9.91e-2)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" 61.8 92.7 43.5 30.4 42.9 42.6 66.6 45.1 60.6 63.6 54.8 112.5 132.5 39.2 82.1 177.6 70.8 87.6 118.3 42.6 45.7 99.2 393.2 49.0 36.0 46.6 44.6 26.3 66.2 102.0 44.6 75.6 46.5 74.9 121.2 7.8 90.6 50.0 104.2 97.1 143.5 57.4 46.6 60.5 72.5 50.6 45.3 35.1 45.8 118.4 64.6 86.7 78.4 48.9 40.8 58.5 28.7 0.3 4.8 15.4 17.7 7.2 66.1 3.2 10.7 62.3 276.3 0.1 158.2 17.5 13.6 74.8 52.7 81.2 4.9 22.3 47.7 174.9 57.3 251.5 13.3 152.7 130.0 53.0 197.2 2.1 12.5 63.9 166.3 0.3 75.9 25.7 23.3 33.9 0.2 24.7 6.5 558.9 59.4 12.7 33.4 54.0 153.0 87.4 71.9 21.6 53.2 83.2 64.8 2.0 52.9 202.2 104.9 5.6 27.3 7.8 6.4 29.7 22.5 9.7 3.8 254.8 12.6 43.8 103.8 30.4 4.1 64.8 2.9 1.3 7.6 3.5 147.0 2.4 2.3 2.6 17.7 26.4 22.2 194.6 37.7 39.4 43.5 42.9 45.1 60.6 42.6 45.7 46.6 44.6 46.5 46.6 45.3 48.9 327.9 25.6 36.6 5.5 7.7 61.1 295.9 316.7 75.7 7.8 99.1 57.3 100.5 205.9 185.5 95.6 25.0 85.3 71.0 168.3 90.1 121.0 6.3 132.5 27.1 238.4 121.8 60.2 19.4 138.6 62.8 31.8 90.2 172.9 43.2 56.9 203.1 419.3 378.1 6.7 24.2 215.1 170.9 107.8 77.8 12.8 44.4 85.3 39.2 49.6 83.6 14.1 27.8 11.6 4.7 121.8 213.1 33.4 7.1 94.6 441.1 277.2 126.6 3.5 13.1 44.6 49.6 4.6 15.1 264.0 124.9 67.2 15.2 43.6 258.2 344.9 MIA CD-RAP ENSG00000261857 "MIA SH3 domain containing" Q16674 19 40771648-40777490 "Cancer-related genes, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 57.9;pituitary gland: 76.2;salivary gland: 43.3;stomach 1: 65.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 51.4;Breast myoepithelial cells: 171.7;Melanocytes: 103.2;monocytes: 30.0;Pancreatic endocrine cells: 66.8;Respiratory ciliated cells: 53.9" "Cancer enriched" "Detected in many" 5 "melanoma: 58.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Group enriched" "Detected in some" 29 "AN3-CA: 90.1;CAPAN-2: 80.6;SK-MEL-30: 271.9;WM-115: 247.7" HPA042369 Approved "Secreted to blood" NA NA 8270000 64000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 4: Stomach - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA042369: AB_10794420" "prognostic favorable (2.08e-4)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "unprognostic (9.02e-3)" "unprognostic (2.27e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-3)" "unprognostic (3.67e-2)" "unprognostic (1.61e-1)" "unprognostic (9.37e-2)" "unprognostic (1.17e-1)" "unprognostic (3.19e-1)" "unprognostic (3.29e-8)" "unprognostic (5.88e-2)" "unprognostic (2.44e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" 2.6 2.9 4.9 6.9 5.9 2.9 57.9 5.7 7.5 8.3 5.4 16.9 2.0 1.2 2.0 6.6 3.7 2.9 5.3 4.4 4.8 2.4 2.7 1.9 2.0 5.3 5.0 7.0 1.4 0.0 76.2 2.1 5.6 6.4 4.2 0.4 43.3 3.3 0.7 9.6 5.9 7.6 4.8 7.0 65.8 1.7 5.5 2.4 2.9 1.7 1.6 4.0 5.2 7.9 0.3 0.9 1.5 90.1 1.3 1.2 1.0 0.0 0.0 0.0 0.5 0.5 80.6 0.2 0.0 0.0 0.3 0.2 0.4 4.9 0.1 2.9 0.9 0.0 1.0 0.1 0.4 0.2 0.4 0.7 4.2 0.0 1.5 1.4 0.0 1.4 0.0 0.9 0.0 0.0 0.1 0.0 0.2 5.9 0.3 0.1 0.2 0.0 2.5 0.0 0.2 0.1 0.1 0.0 271.9 3.4 0.5 1.2 0.0 0.2 3.4 0.1 1.0 0.0 0.2 0.9 0.1 0.4 247.7 0.6 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 4.9 5.9 5.7 7.5 4.4 4.8 5.3 5.0 5.6 4.8 5.5 7.9 1.0 0.0 0.5 0.0 0.3 5.2 0.1 11.2 0.6 0.0 51.4 171.7 0.6 0.0 4.9 0.0 0.0 0.8 0.5 1.7 0.0 0.5 0.0 0.9 0.0 1.4 0.0 0.0 0.0 3.2 0.1 1.1 14.3 0.2 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.1 4.1 0.0 0.7 0.3 0.6 0.2 103.2 0.0 30.0 0.0 0.0 0.0 0.0 66.8 5.1 0.0 0.1 0.8 0.4 0.0 53.9 0.0 0.0 0.2 1.3 0.1 0.6 6.1 1.3 0.7 0.3 0.8 4.1 0.5 MID2 "FXY2, MRX101, RNF60, TRIM1" ENSG00000080561 "Midline 2" Q9UJV3 X 107825755-107931637 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.5;Inhibitory neurons: 21.5;Urothelial cells: 11.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 6 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 41.5;Karpas-707: 35.5;MCF7: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (8.28e-2)" "unprognostic (8.51e-2)" "unprognostic (3.69e-4)" "unprognostic (6.40e-3)" "unprognostic (1.16e-1)" "unprognostic (7.50e-2)" "unprognostic (3.87e-1)" "unprognostic (7.20e-2)" "unprognostic (1.09e-2)" "unprognostic (4.87e-2)" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (3.19e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (3.77e-1)" "unprognostic (5.97e-3)" 11.2 9.2 5.2 3.9 6.1 0.4 7.2 4.4 4.2 8.3 4.2 6.0 1.8 9.4 8.0 13.6 8.8 7.7 3.1 3.5 12.1 6.0 5.4 6.4 4.4 7.4 7.1 9.3 9.6 12.9 3.2 4.4 9.1 10.3 3.6 14.8 11.1 9.6 12.9 9.6 2.6 15.8 6.3 3.8 4.4 2.1 9.0 2.3 13.2 18.5 5.2 10.6 7.5 4.8 8.4 7.1 0.2 11.2 8.8 12.3 0.1 5.9 15.0 5.0 3.6 0.6 1.5 0.0 7.5 11.7 8.3 5.2 4.1 12.1 1.1 0.0 5.5 0.0 4.2 0.0 13.5 0.0 0.0 8.0 13.3 0.1 14.5 9.1 41.5 0.5 0.0 35.5 5.6 26.8 0.1 0.0 1.2 0.3 13.0 0.0 3.2 0.0 6.3 7.5 0.6 0.0 12.6 0.5 18.6 3.9 4.6 0.5 8.2 0.0 2.1 9.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.8 1.4 0.0 0.2 1.6 1.1 0.0 0.0 0.0 0.0 0.1 0.4 5.2 6.1 4.4 4.2 3.5 12.1 7.4 7.1 9.1 6.3 9.0 4.8 3.1 3.2 0.0 8.1 0.4 3.1 3.3 0.9 4.0 1.9 2.3 1.8 0.6 1.5 1.1 0.0 0.0 0.0 0.3 0.3 1.9 1.8 1.1 1.0 1.7 2.6 0.0 0.0 14.5 1.5 0.0 1.5 1.1 1.5 0.0 0.3 2.2 1.8 0.1 0.0 21.5 0.2 0.0 0.0 0.0 1.4 0.0 0.2 3.6 7.5 0.0 0.8 0.0 8.0 7.4 1.1 0.0 0.7 1.1 4.2 0.5 0.8 2.3 3.9 0.0 1.9 2.1 0.2 0.4 3.9 3.7 0.0 1.7 0.8 0.4 11.4 MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 108.0;Oligodendrocytes: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 64.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" 6.3 9.6 3.7 6.2 4.3 5.3 11.1 3.2 5.0 7.5 13.4 12.9 8.8 7.2 12.4 11.5 17.3 7.7 18.4 14.4 4.0 25.4 12.0 7.1 5.1 4.0 5.0 5.4 8.2 14.6 5.4 4.7 4.6 10.9 13.1 6.1 9.7 8.7 13.9 21.4 7.6 7.8 4.0 4.3 8.6 9.8 3.7 6.0 11.1 16.9 7.8 7.7 6.4 4.9 14.6 16.1 7.8 18.4 17.4 23.4 16.6 10.3 16.0 15.1 12.7 21.7 28.1 17.0 10.2 8.4 13.3 35.8 18.1 21.6 18.8 9.9 11.5 7.4 7.0 18.8 14.3 17.5 3.9 11.6 26.4 15.7 13.9 12.7 19.2 12.7 14.5 2.7 24.0 10.8 12.6 9.8 10.8 64.8 16.1 13.8 21.0 14.8 33.7 9.6 18.2 6.1 11.0 17.8 21.8 9.8 18.3 9.7 10.7 9.2 7.6 15.3 11.2 2.6 4.0 9.1 15.9 8.8 11.7 0.0 3.0 1.3 7.4 3.7 9.3 8.7 7.1 6.8 6.5 7.2 6.7 6.7 0.0 10.3 12.0 5.5 5.2 4.0 3.7 4.3 3.2 5.0 14.4 4.0 4.0 5.0 4.6 4.0 3.7 4.9 2.5 16.0 8.6 18.9 5.9 39.9 7.7 13.8 6.2 3.6 6.2 5.8 108.0 11.5 12.6 9.2 6.2 9.8 2.4 8.2 29.4 23.4 8.2 26.0 8.5 5.4 6.0 4.6 43.8 10.6 9.3 8.0 7.1 8.5 2.5 4.2 3.6 5.9 9.7 15.2 47.5 7.1 14.2 3.5 5.0 7.4 6.8 4.3 5.4 12.2 3.4 5.5 5.2 18.1 62.8 8.6 7.0 8.6 4.9 7.5 6.6 25.6 46.3 11.4 0.0 7.3 5.7 9.7 19.0 10.1 42.3 5.1 4.0 8.9 13.6 5.6 MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 196.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 793.4;Intestinal goblet cells: 230.9;Paneth cells: 646.7;Proximal enterocytes: 1115.2;Undifferentiated cells: 220.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 121.4;HaCaT: 90.2;hTCEpi: 82.6;MCF7: 63.2;OE19: 76.9;SK-BR-3: 134.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" 1.3 0.0 0.3 12.1 0.3 0.0 0.9 0.5 0.4 4.4 0.1 95.5 171.0 0.7 0.0 0.3 9.8 11.3 0.0 0.4 0.3 8.8 0.1 9.3 0.1 0.5 0.5 0.3 1.7 0.0 8.1 1.2 0.5 5.6 48.4 0.0 1.0 0.5 0.0 0.6 196.6 3.3 0.2 0.0 22.9 0.5 0.3 0.3 0.1 0.0 0.0 9.0 0.6 0.2 30.4 121.4 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 42.1 44.2 10.8 11.5 0.0 0.1 90.2 0.0 37.7 0.0 0.0 0.1 0.0 47.0 13.3 0.0 0.0 1.9 0.0 82.6 0.3 4.5 0.0 0.0 0.0 0.0 0.4 0.2 63.2 0.1 0.7 0.1 76.9 24.6 0.2 0.4 1.0 30.1 33.7 1.4 0.4 42.9 134.3 0.1 0.1 29.3 0.0 0.0 0.0 14.8 1.8 0.2 0.6 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.4 0.4 0.3 0.5 0.5 0.5 0.2 0.3 0.2 0.1 38.5 8.0 0.3 2.9 0.1 4.5 22.5 0.0 0.0 4.7 2.3 0.5 10.0 39.7 11.0 0.0 0.6 0.0 793.4 1.9 39.9 0.6 40.5 1.5 0.8 58.0 0.0 0.2 46.0 6.0 2.4 56.6 14.3 8.9 0.0 0.0 0.0 0.1 0.0 0.3 230.9 28.5 0.0 0.0 0.9 0.0 0.6 0.0 1.0 0.6 0.0 0.0 0.0 0.2 157.7 646.7 0.0 0.1 41.6 1115.2 27.5 41.3 0.0 0.0 0.0 2.6 0.0 1.2 0.0 0.3 2.1 1.6 0.0 220.7 62.1 MLLT11 AF1Q ENSG00000213190 "MLLT11 transcription factor 7 cofactor" Q13015 1 151060397-151069544 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 54.1;Early spermatids: 76.9;Excitatory neurons: 57.9;Late spermatids: 215.6" "Cancer enriched" "Detected in all" 4 "glioma: 29.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 216.7;EFO-21: 164.9;SH-SY5Y: 238.6;U-698: 207.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000540 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA000540: AB_2666024" "unprognostic (2.96e-2)" "unprognostic (1.98e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.26e-5)" "unprognostic (1.69e-1)" "unprognostic (1.96e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.49e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.25e-12)" "unprognostic (5.66e-3)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (3.94e-3)" 5.3 19.0 59.4 4.7 61.8 2.0 2.5 41.1 109.3 4.5 8.8 7.2 1.6 10.7 1.3 4.0 6.2 6.0 38.1 66.2 80.6 3.8 2.0 3.8 2.1 63.1 50.5 8.2 3.1 16.2 10.4 1.0 66.1 4.3 3.6 35.6 3.8 1.5 11.3 2.6 4.9 13.8 29.9 4.6 5.1 2.8 49.7 20.6 3.8 10.8 2.1 4.0 3.9 57.1 6.3 31.0 216.7 34.4 3.5 5.8 1.4 11.6 15.2 13.2 24.0 3.0 12.6 10.0 164.9 10.6 35.9 4.5 54.3 13.0 7.6 65.8 14.5 28.9 17.7 0.9 6.9 0.8 1.0 9.9 1.6 73.5 2.9 42.2 100.1 43.3 30.8 2.3 43.6 1.4 106.4 19.0 95.7 0.6 4.4 99.8 28.1 0.6 25.5 1.7 132.8 238.6 0.8 1.3 6.9 142.5 5.3 2.7 65.9 27.0 29.0 9.2 24.7 2.4 3.2 207.1 70.0 0.6 51.7 1.1 0.3 1.4 5.9 0.6 2.7 2.5 3.9 6.2 0.7 1.9 5.3 9.1 1.6 4.0 0.9 1.4 4.1 3.2 59.4 61.8 41.1 109.3 66.2 80.6 63.1 50.5 66.1 29.9 49.7 57.1 1.4 0.0 1.1 11.8 4.2 3.6 5.0 14.6 4.6 54.1 2.5 4.8 10.2 1.5 2.2 3.7 8.4 2.9 15.3 0.1 17.6 3.9 76.9 0.8 11.3 5.2 10.7 6.3 57.9 1.2 2.5 17.5 2.0 0.9 4.5 4.3 4.2 0.4 6.0 37.0 40.6 0.1 16.2 6.6 14.5 215.6 2.1 12.3 5.4 10.3 33.3 20.6 19.6 16.1 14.4 3.0 0.2 3.8 4.8 1.3 0.2 2.4 0.6 26.3 0.0 3.4 30.0 8.6 12.3 2.8 3.4 7.4 9.9 3.0 0.2 4.3 MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 609.7" "Group enriched" "Detected in many" 4 "Cholangiocytes: 84.4;Enteroendocrine cells: 90.1;Hepatocytes: 286.6;Proximal enterocytes: 108.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 60.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 46.5;K-562: 15.2;SCLC-21H: 25.5;T-47d: 11.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA064640: AB_2685309" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.06e-3)" "unprognostic (3.46e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (6.13e-3)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (2.46e-2)" "unprognostic (7.72e-3)" 72.3 85.1 5.5 0.7 4.1 0.2 51.2 16.3 9.4 3.0 0.2 7.8 58.8 0.6 16.3 3.4 12.9 5.5 3.5 4.5 1.4 36.2 609.7 2.7 0.0 5.6 1.4 4.9 23.1 6.3 13.4 0.0 6.1 3.7 1.5 0.7 8.7 0.8 58.1 4.5 46.8 0.5 1.3 0.3 4.7 30.9 2.2 0.9 7.3 13.8 0.0 2.0 2.7 2.1 0.2 2.5 0.0 5.9 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.3 7.5 0.0 0.3 0.0 0.6 1.2 0.0 0.0 0.0 0.2 6.1 0.0 4.8 46.5 1.3 0.2 1.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.1 6.3 0.1 0.0 0.7 8.2 1.0 0.0 0.0 1.2 0.0 0.1 25.5 0.7 1.0 4.4 0.0 0.1 11.4 6.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 4.1 16.3 9.4 4.5 1.4 5.6 1.4 6.1 1.3 2.2 2.1 0.6 0.0 16.2 2.3 1.6 1.1 4.8 0.6 0.6 9.9 1.4 1.3 3.4 84.4 4.7 3.7 20.9 0.1 0.3 3.2 1.9 2.9 3.2 0.7 0.2 2.5 90.1 16.0 33.4 1.0 0.1 6.5 4.6 0.8 0.0 0.1 12.8 286.6 0.4 1.7 29.1 19.6 0.0 11.2 1.5 1.2 2.8 2.8 7.2 30.9 0.2 2.0 1.0 2.0 0.9 1.4 13.9 1.2 0.1 2.2 108.9 14.1 3.2 6.5 0.0 23.9 1.0 5.1 1.1 0.5 0.9 0.5 1.7 0.0 31.9 4.0 MMAA cblA ENSG00000151611 "Metabolism of cobalamin associated A" Q8IVH4 4 145599042-145660033 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 24.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037361, HPA058187" Supported Supported Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA037361: AB_10672107, HPA058187: " "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" "prognostic favorable (3.38e-4)" "unprognostic (1.97e-3)" "unprognostic (1.44e-1)" "unprognostic (4.83e-3)" "unprognostic (1.31e-3)" "unprognostic (3.98e-1)" "unprognostic (7.03e-2)" "unprognostic (7.26e-2)" "unprognostic (3.19e-3)" "unprognostic (1.46e-1)" "prognostic favorable (2.23e-5)" "unprognostic (3.40e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "prognostic favorable (3.21e-4)" 4.1 3.2 1.4 3.0 1.9 1.7 4.2 2.7 2.3 3.0 1.3 5.8 7.4 2.4 4.0 4.1 2.7 3.8 3.3 1.5 1.4 7.3 24.5 3.7 3.1 1.3 1.5 2.3 2.0 4.2 0.7 2.8 1.3 2.3 5.3 1.9 3.5 2.8 4.7 3.8 6.2 2.6 1.2 3.5 3.6 4.5 1.3 5.2 3.1 6.0 3.7 4.7 0.8 1.6 2.5 1.4 4.0 2.1 8.4 9.8 1.1 7.1 4.0 2.3 1.4 1.7 4.3 12.1 2.1 4.4 1.1 2.2 2.0 4.4 1.7 7.5 0.8 4.0 1.3 1.5 6.5 5.6 3.3 5.5 6.1 2.6 5.8 3.7 7.2 8.1 1.1 4.6 5.1 3.4 7.2 1.4 1.5 6.2 2.7 3.7 2.2 1.4 13.3 1.3 1.9 1.4 3.5 6.0 3.3 2.4 3.9 1.5 7.0 2.8 1.4 5.0 1.6 2.2 2.0 3.3 4.4 5.5 2.8 3.9 3.1 3.0 4.5 6.1 4.0 3.1 5.3 4.6 3.2 2.6 4.0 5.3 0.5 4.8 7.4 3.3 5.2 2.3 1.4 1.9 2.7 2.3 1.5 1.4 1.3 1.5 1.3 1.2 1.3 1.6 3.6 12.8 5.6 5.5 3.6 2.9 10.4 7.7 5.7 3.4 3.0 2.4 7.6 14.3 13.0 11.0 2.1 7.9 6.5 7.7 15.6 11.1 10.5 5.0 4.5 4.1 2.4 1.7 5.7 12.5 2.8 4.8 7.1 5.7 8.2 3.4 7.9 31.8 4.9 0.0 5.7 6.5 8.2 4.1 1.6 6.3 4.7 3.6 1.8 3.7 5.6 2.3 9.2 8.0 7.4 8.4 7.3 3.0 2.8 6.5 10.9 21.1 6.8 1.6 0.0 4.2 3.8 8.7 5.2 4.4 1.1 7.7 4.5 5.7 6.7 12.2 MMAB "cblB, CFAP23" ENSG00000139428 "Metabolism of cobalamin associated B" Q96EY8 12 109553715-109573580 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 103.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039017 Supported Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "HPA039017: AB_10673603" "unprognostic (1.16e-1)" "unprognostic (1.25e-2)" "unprognostic (1.90e-1)" "unprognostic (1.79e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (4.22e-1)" "unprognostic (2.04e-2)" "unprognostic (5.15e-2)" "unprognostic (1.47e-3)" "unprognostic (2.58e-1)" "prognostic favorable (1.55e-4)" "unprognostic (4.90e-2)" "unprognostic (1.51e-1)" "unprognostic (2.23e-1)" "unprognostic (9.65e-2)" 15.5 51.2 17.8 6.3 18.3 5.8 15.8 18.8 26.9 12.4 18.6 15.8 13.0 10.7 21.2 29.1 13.0 6.0 30.0 17.0 18.8 32.8 103.6 14.9 6.2 22.2 19.0 18.9 23.0 9.8 20.5 4.9 21.3 26.5 7.9 7.3 17.1 6.3 21.1 18.2 14.0 5.6 19.0 12.4 17.7 12.6 18.9 5.5 22.1 16.2 6.5 14.1 14.7 22.9 32.2 22.3 22.2 17.6 8.8 17.7 11.3 7.1 16.2 10.3 10.8 25.8 29.5 21.0 19.9 8.0 19.1 32.9 14.6 54.9 4.6 8.2 60.9 8.6 15.9 42.1 31.3 18.4 7.2 24.0 33.5 22.2 9.7 12.3 9.7 16.4 27.5 15.5 7.3 74.7 16.6 29.2 27.3 3.3 31.6 13.6 8.7 53.9 45.3 30.3 34.1 14.8 15.8 29.2 12.7 6.2 60.5 50.5 5.4 8.6 3.6 6.1 10.4 11.9 9.6 24.0 19.0 22.2 23.9 7.4 7.2 1.0 15.3 10.0 12.2 13.6 11.1 12.1 11.3 17.8 15.2 14.6 1.9 11.2 10.9 9.2 5.8 10.3 17.8 18.3 18.8 26.9 17.0 18.8 22.2 19.0 21.3 19.0 18.9 22.9 25.1 35.3 80.8 9.8 20.4 10.3 33.1 105.6 17.1 32.9 59.6 47.0 52.3 60.1 68.9 42.3 29.2 55.4 15.2 33.6 150.6 49.7 41.3 23.8 10.0 22.1 33.0 34.1 6.4 71.3 37.6 24.7 28.5 16.5 16.5 34.3 28.5 225.3 34.8 104.3 8.5 50.4 71.2 20.4 10.2 82.9 40.4 13.5 26.6 4.7 25.1 30.6 30.9 6.6 21.5 29.7 30.0 30.5 18.1 31.8 61.9 143.6 62.1 29.7 13.1 17.9 26.3 26.0 15.8 44.7 19.7 61.8 16.1 121.1 56.6 30.3 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 2402.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.4;HUVEC TERT2: 12.8;SH-SY5Y: 16.2;U-138 MG: 13.7;WM-115: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 0.7 0.3 4.6 0.3 5.8 0.0 1.8 2.2 5.4 1.7 0.0 0.8 0.1 1.6 0.6 0.4 0.6 2.6 0.8 5.1 3.9 0.1 0.1 0.2 0.2 1.0 1.5 1.0 0.6 0.2 0.5 1.0 1.3 0.9 0.4 0.4 0.3 0.7 0.1 0.2 0.3 1.3 1.4 0.4 0.3 0.4 3.0 0.4 1.0 0.5 0.2 0.9 0.5 3.3 0.0 0.2 7.9 29.4 1.0 2.0 0.0 10.9 1.6 3.0 1.8 0.0 0.1 0.0 0.0 4.9 1.8 0.0 5.8 0.0 3.7 0.0 3.4 0.0 0.0 0.0 2.4 0.0 0.5 1.4 0.0 4.4 1.3 5.4 12.8 0.1 0.0 1.1 1.7 0.0 0.0 0.0 1.7 0.0 3.0 0.3 0.6 0.0 0.6 0.1 0.2 16.2 0.0 0.0 0.2 2.2 1.1 0.0 7.1 13.7 7.7 0.2 4.2 0.0 0.0 0.0 5.7 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 2.2 5.4 5.1 3.9 1.0 1.5 1.3 1.4 3.0 3.3 2.2 0.0 0.0 20.5 0.1 1.1 0.0 0.0 0.6 4.4 0.8 1.4 1.0 0.0 0.0 0.0 2.1 0.1 0.1 0.0 1.9 0.0 6.5 0.5 15.9 5.2 0.0 0.0 443.4 0.0 0.1 16.0 0.0 0.4 0.0 1.9 1.4 0.0 0.4 1.7 300.3 0.0 0.0 0.0 1.6 6.5 0.9 0.4 1.8 10.3 0.0 3.0 0.0 2402.1 13.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.7 2.9 0.0 1.1 0.2 0.1 0.0 0.2 3.4 0.0 0.1 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 90.5;Leydig cells: 98.2;NK-cells: 64.9;Peritubular cells: 177.9" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.3" "Cell line enhanced" "Detected in some" "HHSteC: 4.4;NTERA-2: 2.7;PC-3: 1.9;U-266/70: 3.9" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.19e-2)" "unprognostic (6.31e-2)" "unprognostic (6.70e-3)" "unprognostic (1.29e-1)" "unprognostic (3.99e-2)" "unprognostic (9.31e-2)" "unprognostic (6.94e-2)" "unprognostic (1.20e-1)" "unprognostic (8.06e-2)" "unprognostic (8.37e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.26e-11)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-2)" "unprognostic (6.66e-2)" 7.1 2.8 0.4 0.3 0.5 1.3 4.1 0.1 1.0 16.7 0.0 5.0 1.9 15.4 0.0 2.8 11.0 2.9 15.0 0.3 0.0 3.2 3.3 14.3 1.1 0.4 0.0 29.9 1.6 0.0 5.7 2.8 0.1 11.8 0.1 0.1 1.0 1.1 0.5 3.1 3.4 1.2 0.0 3.0 4.3 5.2 0.1 0.0 2.4 0.0 0.1 11.9 10.9 0.2 0.6 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.4 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.5 0.2 1.2 4.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.4 0.0 0.2 2.7 0.0 1.9 0.9 0.0 1.1 0.0 0.0 0.4 0.2 0.3 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.3 0.0 3.9 0.2 1.1 0.0 0.2 0.1 0.0 0.2 0.0 1.5 0.0 0.9 0.0 0.3 1.0 0.0 0.1 0.0 0.7 0.1 2.2 0.1 11.3 0.3 1.7 0.4 0.5 0.1 1.0 0.3 0.0 0.4 0.0 0.1 0.0 0.1 0.2 2.2 0.0 0.5 1.0 1.1 13.4 0.8 0.7 0.6 1.3 1.7 1.5 9.6 1.5 0.4 1.8 0.0 4.0 27.4 3.0 0.0 1.2 1.0 4.0 3.5 2.2 3.0 2.7 0.3 0.5 2.2 90.5 4.6 1.0 0.0 1.4 12.1 1.0 5.7 3.3 0.6 1.9 4.1 1.0 18.5 6.2 98.2 1.3 19.6 0.0 1.2 0.5 64.9 0.0 0.2 4.3 0.9 177.9 4.3 0.5 2.7 1.0 0.5 7.7 0.0 0.7 5.3 2.1 10.5 0.7 15.8 10.3 8.1 2.1 1.7 0.9 MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 509.9;salivary gland: 267.9;urinary bladder: 211.2" "Cell type enriched" "Detected in many" 8 "Ductal cells: 8176.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 145.9;CAPAN-2: 815.9;EFO-21: 189.8;RPTEC TERT1: 350.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 2810000 35000 "Cluster 5: Breast - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" 3.8 0.1 0.0 2.0 0.0 0.3 168.7 0.0 0.3 13.3 0.0 1.6 0.6 97.4 27.9 21.3 91.2 509.9 0.2 0.0 0.0 140.2 3.4 31.6 1.9 0.0 0.0 0.7 85.2 0.0 0.3 0.8 0.0 54.0 1.0 0.0 267.9 34.9 0.1 32.4 0.6 4.8 0.0 0.2 7.3 0.6 0.4 3.3 0.4 0.0 29.3 211.2 1.7 0.0 0.2 145.9 0.0 0.4 0.0 0.0 0.2 0.0 2.1 0.1 0.1 1.9 815.9 0.0 189.8 0.0 0.0 1.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.6 1.0 0.1 0.2 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.5 11.8 0.0 0.0 0.0 0.0 350.1 1.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.1 0.0 0.7 3.0 0.0 1.6 0.1 0.6 0.4 1.0 5.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 86.6 43.3 0.0 1.5 1.0 382.2 135.4 1.2 0.0 124.2 93.7 0.7 100.1 401.2 1017.0 0.0 0.7 2.9 1.2 0.0 8176.2 6.1 62.1 3.3 8.8 0.0 0.0 0.0 209.4 0.3 3.4 0.0 124.6 2.5 0.0 0.0 0.0 98.0 0.0 0.0 0.0 38.7 0.6 0.3 10.3 11.8 12.6 0.0 0.0 65.2 0.0 0.0 0.0 0.0 850.9 0.0 0.0 0.1 603.3 0.0 33.9 72.6 0.0 0.0 0.0 31.4 0.1 0.2 17.0 2.4 0.8 3.6 0.0 2.3 840.8 MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Endothelial cells: 158.0;Hepatic stellate cells: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cell line enriched" "Detected in some" 13 "HUVEC TERT2: 1242.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" 22.6 3.8 0.8 10.9 0.8 1.8 27.3 0.8 1.1 28.5 1.4 9.9 5.4 15.0 2.8 14.5 23.1 21.1 3.6 0.6 0.9 1.1 8.7 16.1 14.0 1.4 1.4 4.9 3.4 0.5 0.7 40.1 1.2 3.8 14.9 0.5 2.7 4.6 1.1 8.2 13.5 16.8 1.1 0.6 5.2 12.7 1.5 3.7 23.1 6.6 7.6 19.6 9.8 1.1 0.0 0.0 94.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1242.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 6.3 0.0 2.2 0.2 1.2 0.8 0.8 0.8 1.1 0.6 0.9 1.4 1.4 1.2 1.1 1.5 1.1 15.4 0.0 12.0 0.3 2.3 4.2 0.1 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.6 0.0 0.0 0.0 3.9 0.0 1.9 0.0 17.7 0.3 0.7 158.0 0.0 25.9 0.2 0.0 0.0 1.9 0.0 0.4 2.5 0.1 146.3 2.4 0.6 0.0 0.1 0.0 0.0 5.7 5.9 7.7 0.3 9.1 1.8 21.5 0.7 0.8 2.1 0.0 0.4 0.0 0.0 0.0 5.0 0.4 0.0 0.0 1.5 0.4 0.0 0.3 0.9 15.4 0.0 0.8 4.5 0.0 1.6 0.0 0.0 0.1 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MMS22L "C6orf167, dJ39B17.2" ENSG00000146263 "MMS22 like, DNA repair protein" Q6ZRQ5 6 97142161-97283217 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 67.8;Oligodendrocytes: 52.3;Spermatocytes: 56.9;Spermatogonia: 45.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA067042 Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA067042: AB_2685768" "unprognostic (3.61e-2)" "unprognostic (2.80e-1)" "unprognostic (2.26e-2)" "unprognostic (1.97e-3)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.00e-5)" "unprognostic (9.63e-2)" "unprognostic (5.81e-3)" "unprognostic (8.21e-3)" "unprognostic (9.39e-2)" "unprognostic (6.58e-2)" "unprognostic (1.34e-6)" "unprognostic (3.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" 1.1 1.1 0.7 2.0 1.8 7.0 2.3 1.3 1.2 1.6 0.7 1.6 1.2 1.5 0.5 1.7 1.4 1.0 0.7 0.7 1.0 0.8 0.9 1.1 3.4 2.1 1.4 1.4 1.3 1.4 0.5 2.0 1.8 1.3 2.3 2.4 1.0 0.8 0.6 2.9 1.6 1.5 1.2 1.4 1.1 6.8 1.5 5.2 1.1 0.5 3.4 1.3 1.1 2.4 7.5 8.2 13.5 14.8 2.2 4.0 10.6 15.0 6.9 13.8 20.1 11.4 8.6 16.4 9.0 5.7 16.0 13.4 17.1 8.3 27.4 14.1 12.7 16.7 11.3 7.2 1.3 25.8 11.3 2.2 4.3 19.5 9.0 2.8 6.0 15.2 23.1 25.6 13.1 8.9 9.5 10.4 5.2 12.1 6.1 15.8 12.8 5.8 5.9 9.7 7.7 6.6 9.8 4.9 4.0 7.6 7.6 15.7 4.5 14.0 13.3 11.8 20.8 3.2 10.3 18.3 8.0 16.0 15.7 0.5 0.4 0.9 0.6 0.7 1.0 0.5 0.9 1.0 1.1 0.7 0.8 1.1 0.4 0.6 1.6 1.2 0.9 0.4 0.7 1.8 1.3 1.2 0.7 1.0 2.1 1.4 1.8 1.2 1.5 2.4 5.9 3.2 8.6 16.6 9.7 9.2 5.8 4.0 4.0 11.6 6.1 6.2 4.2 5.7 6.9 3.7 41.7 12.5 14.6 3.3 1.9 2.9 67.8 4.4 6.1 6.5 1.2 26.3 11.3 4.1 11.2 6.1 7.7 2.8 7.6 24.0 10.8 3.1 6.4 3.3 7.7 8.4 8.2 7.5 6.0 17.2 9.9 6.8 7.2 36.5 6.4 6.1 6.2 22.6 52.3 3.0 2.0 5.7 13.1 2.9 5.4 0.8 6.1 31.9 6.6 7.9 5.1 56.9 45.8 7.1 8.2 3.6 9.6 5.2 10.3 3.0 MORC4 "FLJ11565, ZCW4, ZCWCC2" ENSG00000133131 "MORC family CW-type zinc finger 4" Q8TE76 X 106813871-107000212 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 79.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 131.4;Alveolar cells type 2: 130.4;Cytotrophoblasts: 329.8;Syncytiotrophoblasts: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000395, HPA015547, HPA050250" Enhanced Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA000395: AB_1079405, HPA015547: AB_2669216, HPA050250: AB_2681063" "prognostic unfavorable (3.56e-5)" "unprognostic (3.30e-3)" "unprognostic (1.09e-1)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (6.29e-3)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (5.56e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.60e-2)" "unprognostic (6.57e-2)" "unprognostic (4.89e-2)" "unprognostic (8.69e-2)" 13.4 30.9 24.8 7.8 35.5 11.8 12.2 47.8 51.0 12.1 17.8 8.5 10.4 11.5 16.3 9.6 10.4 10.1 7.0 32.4 22.4 10.8 21.1 8.8 5.6 11.1 11.4 17.4 15.1 11.7 6.2 79.9 16.6 12.4 10.8 22.3 10.9 11.5 20.2 18.7 10.0 11.4 3.9 6.0 8.4 20.2 16.6 5.6 10.2 10.3 7.0 7.5 11.1 55.7 29.8 121.0 11.4 26.4 35.0 40.3 60.5 28.7 30.8 14.6 18.3 64.6 13.1 3.7 14.2 30.5 23.9 22.5 39.8 25.5 17.1 4.6 23.0 6.4 40.7 27.1 25.6 4.7 13.9 20.8 24.3 19.6 28.6 85.7 13.1 4.1 3.9 41.4 32.7 26.7 10.7 6.4 8.9 82.0 45.2 4.2 22.9 4.3 47.0 23.3 9.2 11.5 35.4 33.9 23.0 15.9 19.7 5.0 12.6 22.5 21.4 44.7 15.7 11.1 16.2 11.5 24.0 3.8 16.2 8.3 1.5 1.8 1.9 1.3 1.7 1.7 1.9 1.5 0.7 2.7 2.1 1.7 3.7 1.5 1.7 2.5 1.5 0.4 24.8 35.5 47.8 51.0 32.4 22.4 11.1 11.4 16.6 3.9 16.6 55.7 8.6 131.4 130.4 6.2 5.1 17.5 19.1 4.9 21.1 5.4 11.5 9.5 3.0 10.0 61.8 5.5 4.2 329.8 10.4 3.6 21.5 9.9 0.9 6.2 11.5 13.6 1.8 0.4 4.2 7.4 28.2 33.4 10.2 15.5 66.3 10.3 7.5 24.0 23.4 1.7 6.5 10.5 6.1 2.1 5.0 1.8 11.1 8.2 12.4 3.7 0.3 6.7 3.1 15.1 8.7 7.5 6.7 11.7 5.8 16.4 4.4 12.7 62.2 7.2 26.3 16.9 12.0 9.9 26.6 19.7 16.1 257.8 11.9 10.1 10.1 11.8 MOV10 "fSAP113, gb110, MGC2948" ENSG00000155363 "Mov10 RISC complex RNA helicase" Q9HCE1 1 112673141-112700746 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031627 Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA031627: AB_2673966" "unprognostic (1.44e-2)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" "unprognostic (6.82e-3)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.44e-4)" "unprognostic (9.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.58e-3)" "unprognostic (2.85e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.48e-11)" "unprognostic (4.01e-2)" "unprognostic (3.61e-1)" "unprognostic (1.46e-3)" "unprognostic (1.21e-3)" 7.6 13.2 3.4 9.7 3.7 4.7 7.6 2.9 3.4 10.2 4.7 10.9 22.1 10.2 9.5 13.2 13.5 9.4 5.2 3.1 6.2 10.3 19.4 9.1 8.5 4.7 4.1 9.7 8.2 12.8 11.2 23.6 4.0 11.5 10.7 3.0 14.3 11.2 3.1 27.2 20.2 10.8 4.1 12.1 10.7 16.6 5.4 16.2 9.8 4.2 7.0 9.3 10.8 3.4 29.5 17.9 10.4 40.2 8.3 23.5 39.1 19.8 46.5 56.9 80.7 33.2 31.7 0.0 13.2 27.4 21.1 30.5 39.7 47.4 19.6 32.4 24.2 20.2 26.7 37.8 35.3 8.5 19.3 39.9 14.2 34.6 10.9 37.4 49.2 40.7 27.2 9.8 17.8 54.7 32.7 6.6 23.4 12.2 18.1 57.9 26.2 1.3 26.4 31.9 4.4 15.0 40.9 27.5 31.5 20.2 21.4 19.4 29.7 17.6 31.0 12.4 17.8 11.3 3.3 0.1 34.9 17.4 51.4 0.9 3.5 0.7 12.5 10.3 12.4 2.1 10.8 11.1 6.8 1.5 10.3 8.0 1.1 12.7 12.2 1.0 10.2 7.6 3.4 3.7 2.9 3.4 3.1 6.2 4.7 4.1 4.0 4.1 5.4 3.4 13.0 9.6 10.5 26.4 6.3 8.8 10.4 15.5 8.0 2.4 7.8 7.0 4.1 8.6 17.4 16.5 0.0 54.7 5.6 29.2 3.9 15.5 5.9 5.8 7.3 16.9 15.0 3.8 4.1 15.5 18.4 9.4 23.9 7.0 1.3 36.5 16.8 18.3 15.8 5.0 2.3 18.0 12.2 7.5 6.0 6.2 9.3 10.3 3.6 12.2 14.4 15.1 10.3 18.1 3.3 12.4 26.9 7.5 3.6 11.1 46.2 13.9 18.4 1.1 13.1 4.0 7.4 2.7 3.4 11.7 7.0 38.2 9.2 22.4 15.5 12.1 MPDZ MUPP1 ENSG00000107186 "Multiple PDZ domain crumbs cell polarity complex component" O75970 9 13105706-13279692 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 85.7" "Cell type enhanced" "Detected in many" "Astrocytes: 121.5;Excitatory neurons: 213.6;Inhibitory neurons: 271.3;Oligodendrocyte precursor cells: 158.8;Oligodendrocytes: 279.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 58.1;HUVEC TERT2: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013512, HPA020255, HPA026686" Enhanced NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB013512: AB_2533517, HPA020255: AB_1854073, HPA026686: AB_1854074" "unprognostic (1.55e-1)" "unprognostic (4.21e-3)" "unprognostic (4.09e-3)" "unprognostic (1.68e-1)" "unprognostic (4.28e-2)" "unprognostic (1.03e-1)" "prognostic favorable (8.68e-4)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.50e-1)" "prognostic favorable (7.40e-4)" "unprognostic (1.54e-1)" "unprognostic (2.59e-3)" "unprognostic (1.32e-3)" "unprognostic (2.50e-1)" "unprognostic (1.58e-1)" "unprognostic (9.74e-2)" 22.7 9.9 18.0 5.3 23.2 0.2 13.2 20.3 20.6 14.3 21.7 16.1 2.8 17.8 15.3 7.6 17.5 11.7 29.8 18.0 20.4 18.8 85.7 11.1 3.9 19.8 22.4 25.6 4.6 11.3 10.7 24.7 20.3 19.2 5.3 33.0 6.3 23.2 19.9 3.8 6.4 18.6 21.4 11.1 7.6 11.5 17.7 4.3 11.7 31.3 1.8 12.6 9.9 35.3 16.1 21.2 58.1 26.0 39.2 35.4 11.8 15.9 16.4 13.8 13.1 0.0 0.0 0.0 4.5 39.6 14.2 0.3 17.3 8.8 22.3 0.0 10.2 10.5 21.9 3.9 20.8 0.1 5.4 26.5 3.6 9.7 6.6 35.3 53.5 0.0 0.3 0.1 12.5 4.2 0.0 0.2 24.9 0.0 9.0 0.0 14.2 0.0 13.7 8.5 7.2 26.9 12.6 2.8 15.5 39.7 8.1 0.1 42.8 14.1 2.7 4.7 12.4 0.0 0.0 0.0 6.8 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 23.2 20.3 20.6 18.0 20.4 19.8 22.4 20.3 21.4 17.7 35.3 70.9 32.1 7.9 121.5 0.2 5.1 10.1 4.8 3.4 30.9 8.6 15.6 109.7 1.5 14.7 7.3 39.6 16.1 0.4 0.1 1.9 4.2 4.2 27.0 12.4 44.6 1.8 2.1 213.6 2.0 22.9 27.4 1.5 6.3 1.3 39.5 42.5 74.4 5.8 26.9 271.3 0.2 6.1 0.6 6.8 3.7 24.2 0.9 17.8 60.9 0.6 40.2 0.0 158.8 279.6 1.8 0.0 33.8 0.1 12.9 0.0 16.4 36.6 25.4 39.5 35.1 40.8 6.7 13.9 0.1 4.0 10.8 0.8 7.6 0.0 4.7 MPV17L "FLJ39599, MLPH1, MLPH2, MPV17L1" ENSG00000156968 "MPV17 mitochondrial inner membrane protein like" Q2QL34 16 15395754-15413271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 14.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 29.5;SK-BR-3: 8.2" "Low region specificity" "Detected in all" HPA041180 Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041180: AB_10794266" "unprognostic (9.65e-2)" "unprognostic (8.74e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (2.73e-1)" "unprognostic (4.38e-3)" "unprognostic (8.41e-2)" "unprognostic (8.99e-3)" "unprognostic (8.70e-2)" "unprognostic (6.36e-3)" "prognostic favorable (1.48e-11)" "unprognostic (2.84e-1)" "unprognostic (7.60e-2)" "unprognostic (6.61e-3)" "unprognostic (3.87e-2)" 1.8 2.5 1.2 1.8 0.1 4.4 6.4 1.9 2.2 2.8 0.0 2.3 3.4 2.0 0.3 1.0 1.8 2.4 1.6 0.1 0.0 3.3 9.1 0.9 2.3 0.1 0.0 2.1 14.1 2.4 3.2 0.6 0.3 2.0 1.0 4.4 7.1 1.8 8.0 4.5 2.3 0.8 0.0 1.8 1.8 1.0 0.5 0.2 2.2 2.4 0.6 1.9 1.3 0.4 1.0 1.9 0.8 0.8 0.2 0.1 1.2 0.5 0.0 0.0 0.0 1.9 3.4 1.5 1.3 0.6 0.5 1.5 3.0 0.0 0.0 1.2 0.8 5.9 4.6 3.9 0.3 3.6 29.5 0.3 0.4 0.1 0.2 0.5 0.0 1.6 2.3 3.3 0.1 1.9 1.4 2.3 1.7 0.3 0.1 2.0 0.6 1.6 0.5 0.8 4.8 1.6 2.7 8.2 0.2 0.9 1.8 2.6 2.6 1.3 0.8 1.1 1.1 1.4 0.6 1.7 0.7 1.7 0.5 1.7 1.2 0.2 0.8 0.9 0.6 0.8 0.5 0.8 0.4 1.2 0.4 0.8 1.8 1.1 0.4 0.7 0.4 0.6 1.2 0.1 1.9 2.2 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.4 2.5 6.4 8.8 3.9 2.0 7.9 14.4 8.2 0.0 12.8 11.4 6.0 6.0 14.3 13.1 0.0 10.4 0.5 4.1 2.7 15.6 7.5 4.6 5.4 9.2 6.6 1.2 2.1 5.6 12.9 0.5 8.1 2.0 10.7 6.3 7.6 4.2 29.1 1.0 8.4 5.9 8.7 2.0 13.6 20.6 0.8 7.2 6.0 21.4 2.8 0.7 6.2 0.0 7.5 3.2 5.9 15.3 14.3 1.4 9.6 9.3 19.9 21.0 16.6 0.0 23.5 6.7 9.0 2.0 0.6 11.5 0.5 9.9 4.4 12.1 10.1 MPZL3 ENSG00000160588 "Myelin protein zero like 3" Q6UWV2 11 118226690-118252365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.3;skin 1: 30.4" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 43.8;Suprabasal keratinocytes: 63.9;T-cells: 44.3;Urothelial cells: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 6 "basophil: 44.3;eosinophil: 99.4;MAIT T-cell: 28.9;neutrophil: 87.8" "Group enriched" "Detected in all" 8 "granulocytes: 99.4;T-cells: 28.9" "Cell line enhanced" "Detected in many" "CAPAN-2: 26.3;HMC-1: 29.0;MCF7: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029116 Approved "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA029116: AB_10610142" "unprognostic (2.54e-2)" "unprognostic (1.24e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (3.13e-3)" "unprognostic (1.52e-1)" "unprognostic (8.74e-3)" "unprognostic (2.86e-2)" "unprognostic (9.82e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (4.98e-4)" "unprognostic (4.86e-2)" "unprognostic (1.58e-2)" "unprognostic (1.89e-1)" "unprognostic (3.90e-1)" "prognostic favorable (3.64e-4)" "unprognostic (1.20e-1)" 3.3 0.5 0.7 4.7 1.0 7.3 8.2 2.8 0.7 11.5 1.7 5.6 5.4 1.5 4.9 33.3 5.4 7.6 1.6 0.7 0.8 3.1 7.5 7.9 4.8 1.0 0.7 0.5 7.2 6.7 3.8 0.8 0.9 5.6 6.1 1.3 11.7 2.7 1.7 30.4 5.3 1.5 0.7 6.0 6.8 1.1 0.8 2.8 6.1 0.9 12.6 4.4 16.8 0.7 5.0 0.6 0.0 0.7 0.0 0.0 0.7 0.6 0.1 0.1 0.1 16.7 26.3 4.9 12.5 0.0 1.9 6.8 1.2 5.6 0.1 0.3 2.0 3.0 1.4 8.1 0.2 4.1 29.0 0.3 13.6 0.0 5.4 0.0 8.8 3.3 3.8 2.7 0.1 17.1 1.9 2.2 2.4 16.5 1.2 0.0 0.0 7.4 10.0 6.2 3.4 0.3 6.6 8.6 0.5 1.3 15.4 2.2 4.3 0.1 1.3 0.1 0.1 0.4 5.1 3.1 0.1 0.1 0.3 44.3 6.0 99.4 7.0 3.7 28.9 1.7 11.3 9.6 8.1 1.9 8.4 6.9 87.8 8.2 2.6 1.1 8.4 5.3 0.7 1.0 2.8 0.7 0.7 0.8 1.0 0.7 0.9 0.7 0.8 0.7 2.4 16.0 26.9 0.0 4.9 35.6 21.7 11.8 9.6 0.3 28.2 14.7 1.7 5.7 15.9 9.2 2.1 0.6 9.6 19.6 0.0 10.5 7.4 32.7 4.1 4.9 12.0 0.4 2.2 8.8 0.7 1.6 18.3 34.0 1.3 0.1 2.2 8.2 1.3 0.0 2.3 5.1 14.2 5.1 18.7 7.7 0.0 5.5 10.6 1.9 3.8 0.3 4.1 0.5 0.3 16.7 9.1 0.4 6.6 30.6 9.3 1.1 43.8 1.7 0.0 0.4 2.3 1.7 0.8 14.3 63.9 1.6 44.3 0.2 8.1 46.4 MRAS "M-RAs, R-RAS3, RRAS3" ENSG00000158186 "Muscle RAS oncogene homolog" O14807 3 138347648-138405534 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 202.3;heart muscle: 132.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 121.7;Distal tubular cells: 58.7;Theca cells: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "non-classical monocyte: 25.0" "Lineage enriched" "Detected in many" 9 "monocytes: 25.0" "Cell line enhanced" "Detected in many" "BJ: 92.9;EFO-21: 113.7;fHDF/TERT166: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042728 Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol Vesicles "HPA042728: AB_10796582" "unprognostic (1.96e-1)" "unprognostic (2.95e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.69e-1)" "unprognostic (5.32e-2)" "unprognostic (8.96e-2)" "unprognostic (3.85e-3)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (3.18e-3)" "unprognostic (1.78e-2)" "unprognostic (6.25e-2)" "unprognostic (2.21e-1)" "unprognostic (4.23e-2)" 91.9 67.7 112.7 10.8 130.6 1.7 46.7 118.2 105.5 17.3 48.9 24.2 3.3 28.7 7.1 7.9 26.4 12.0 132.9 105.6 132.8 22.9 5.5 18.4 5.2 126.1 135.9 48.6 5.7 8.2 17.7 10.6 112.9 15.3 4.1 15.9 13.4 15.0 80.4 12.2 8.7 23.2 110.3 12.2 12.0 9.6 202.3 4.9 26.4 48.0 3.3 29.1 12.1 97.8 0.8 7.9 15.8 24.5 59.6 29.2 40.0 92.9 16.0 7.3 8.2 3.3 3.1 0.3 113.7 70.4 18.6 0.1 9.0 1.8 6.1 7.7 3.1 0.5 4.8 20.1 15.9 0.0 1.9 41.5 5.9 0.7 1.4 13.6 1.3 0.0 10.7 0.8 31.4 3.7 0.0 20.4 19.1 0.0 2.7 1.1 33.8 0.2 30.4 2.0 18.6 42.0 62.8 0.7 45.9 10.9 16.1 37.7 0.6 23.7 25.3 24.3 2.4 0.1 1.0 1.2 21.4 0.1 11.4 0.2 2.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.3 0.8 25.0 0.1 0.0 0.8 112.7 130.6 118.2 105.5 105.6 132.8 126.1 135.9 112.9 110.3 202.3 97.8 8.9 9.6 1.5 54.2 0.8 2.2 3.0 3.4 1.2 5.6 28.8 34.8 121.7 2.8 3.5 9.2 10.4 20.1 0.2 0.0 58.7 8.6 11.6 1.0 21.4 14.5 1.8 0.0 25.5 3.2 3.2 23.0 2.0 1.5 6.3 35.2 12.8 1.6 26.3 28.6 20.6 0.0 2.0 15.1 18.4 40.0 23.3 18.2 28.4 20.6 12.2 24.3 0.0 28.6 11.0 3.8 0.0 34.3 0.1 3.3 0.0 27.5 1.3 9.6 6.6 20.8 18.9 7.3 18.6 0.4 1.0 14.4 0.8 59.1 0.0 0.6 MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 122.3" "Group enriched" "Detected in many" 4 "Breast glandular cells: 128.9;Hepatic stellate cells: 397.7;Hofbauer cells: 176.1;Kupffer cells: 361.4;Macrophages: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Group enriched" "Detected in some" 19 "MOLT-4: 19.3;TIME: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" 54.4 28.7 0.8 24.0 1.7 0.7 16.3 0.3 3.5 17.2 9.2 16.1 9.9 7.2 1.7 13.1 11.9 27.7 10.2 1.1 0.7 7.6 40.9 122.3 15.2 1.4 0.9 6.2 8.1 4.6 1.5 54.3 1.1 2.2 18.5 0.1 4.9 8.0 1.8 2.8 17.5 30.3 0.7 50.6 9.7 7.5 2.8 8.0 5.5 8.7 3.0 29.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 19.3 0.0 0.2 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 1.7 0.3 3.5 1.1 0.7 1.4 0.9 1.1 0.7 2.8 1.3 4.0 32.1 43.5 1.3 3.5 0.4 0.0 0.0 0.0 0.0 128.9 1.7 3.6 11.5 7.4 0.0 0.0 0.9 1.0 1.4 0.0 0.1 27.3 0.0 0.1 39.0 0.0 3.2 0.8 0.4 1.4 2.5 0.0 0.1 13.9 0.1 397.7 13.1 176.1 0.0 1.3 0.9 0.0 361.4 46.8 19.4 1.5 316.5 0.0 60.9 0.5 0.0 0.0 0.5 0.5 0.1 1.5 0.0 1.0 0.0 2.2 0.1 5.8 0.0 32.9 3.0 2.2 0.4 2.3 1.2 0.4 2.1 4.7 1.7 0.8 0.1 MRPL19 "KIAA0104, MRP-L15, RLX1, RPML15" ENSG00000115364 "Mitochondrial ribosomal protein L19" P49406 2 75646783-75690851 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 167.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046805, HPA056622" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046805: AB_2679816, HPA056622: AB_2683195" "unprognostic (9.24e-2)" "unprognostic (3.84e-2)" "prognostic favorable (7.39e-4)" "unprognostic (8.40e-2)" "unprognostic (1.59e-2)" "unprognostic (7.52e-3)" "unprognostic (5.75e-2)" "unprognostic (9.86e-2)" "unprognostic (6.21e-3)" "unprognostic (9.71e-3)" "prognostic unfavorable (1.97e-5)" "unprognostic (2.42e-1)" "unprognostic (3.67e-2)" "unprognostic (1.55e-1)" "unprognostic (3.30e-1)" "unprognostic (1.12e-1)" "unprognostic (1.20e-1)" 31.3 30.1 21.8 18.9 27.4 13.9 28.6 26.5 23.5 29.1 14.8 27.8 23.7 21.7 25.2 25.0 18.1 20.7 35.0 18.8 26.7 56.0 63.7 17.8 20.3 23.4 24.4 17.4 23.6 45.2 12.2 25.7 25.4 21.6 30.9 19.3 24.1 25.1 66.4 23.9 19.9 29.0 26.8 16.9 18.4 16.5 24.9 24.3 36.9 44.8 25.1 24.5 15.1 32.5 100.7 57.5 53.3 48.3 57.0 68.1 75.6 63.4 57.0 78.5 62.2 88.5 40.6 56.5 62.1 69.2 73.8 69.5 83.7 95.8 117.8 63.2 72.4 77.4 44.4 114.3 61.0 82.9 44.5 45.6 72.4 79.7 72.3 49.6 84.1 60.8 86.4 32.3 78.5 61.9 76.1 64.9 69.9 102.9 65.2 94.5 116.5 74.5 134.1 61.9 58.8 50.2 62.2 71.2 72.4 53.3 61.1 32.8 57.0 68.3 75.4 61.2 94.6 33.3 53.8 47.1 53.9 81.0 61.1 17.7 20.2 14.2 22.1 26.8 25.1 26.8 22.7 23.8 29.7 22.7 19.9 24.6 1.4 24.4 24.9 35.0 26.5 17.2 21.8 27.4 26.5 23.5 18.8 26.7 23.4 24.4 25.4 26.8 24.9 32.5 31.8 19.2 29.6 10.7 27.4 29.1 28.6 77.8 21.1 38.3 32.4 29.5 40.2 25.8 49.4 49.7 52.1 90.3 26.3 24.0 125.2 88.7 27.6 42.7 48.4 27.7 27.6 32.8 13.9 61.1 87.3 33.7 36.7 50.3 19.0 35.8 27.1 67.6 47.3 48.8 14.3 36.5 44.7 14.6 17.0 11.2 35.4 23.7 33.8 12.2 35.0 39.6 34.0 15.1 20.0 53.6 27.7 36.5 36.5 36.1 36.5 167.7 32.8 50.9 19.7 31.4 38.1 55.5 17.6 44.3 28.3 57.7 25.3 62.2 50.7 35.6 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 MSH3 "DUP, MRP1" ENSG00000113318 "MutS homolog 3" P20585 5 80654652-80876815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 95.1;Inhibitory neurons: 98.9;Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036081 Approved "Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear bodies" "HPA036081: AB_10673229" "unprognostic (1.91e-1)" "unprognostic (7.61e-2)" "prognostic favorable (5.90e-5)" "unprognostic (2.95e-2)" "unprognostic (1.89e-1)" "unprognostic (6.41e-2)" "unprognostic (1.81e-1)" "unprognostic (8.70e-2)" "unprognostic (3.17e-2)" "unprognostic (2.62e-2)" "unprognostic (2.63e-1)" "unprognostic (3.91e-1)" "prognostic favorable (1.77e-4)" "unprognostic (5.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" 9.4 4.6 1.8 4.3 2.4 5.0 5.5 1.6 2.0 6.6 1.5 6.0 6.0 5.2 5.3 5.0 7.0 5.7 4.9 1.7 2.0 12.5 11.4 4.2 4.9 1.7 2.0 5.3 5.2 8.8 3.3 4.3 1.7 5.2 6.2 3.7 4.5 5.2 5.1 5.1 5.6 5.1 2.2 4.1 5.0 3.9 2.5 7.1 10.8 4.7 6.1 6.3 3.9 2.0 12.4 15.0 11.7 13.1 6.6 12.3 16.6 12.2 11.8 13.6 16.7 10.0 15.6 22.2 14.0 15.3 12.8 10.4 15.6 20.5 17.3 14.2 13.9 8.4 13.4 9.9 6.8 9.9 8.5 10.9 9.5 15.8 16.6 13.8 12.9 7.9 12.1 12.9 16.1 11.9 19.0 4.7 9.0 4.8 7.7 13.2 24.2 16.4 15.2 13.0 11.6 13.9 10.4 11.5 13.0 14.4 15.2 9.4 12.4 7.8 9.5 6.2 23.0 8.7 15.6 21.6 12.2 16.8 10.2 0.7 2.9 1.9 3.3 3.4 3.8 3.4 3.5 3.6 3.3 2.2 2.6 2.6 1.7 3.1 4.6 2.8 4.8 2.4 1.8 2.4 1.6 2.0 1.7 2.0 1.7 2.0 1.7 2.2 2.5 2.0 16.7 35.3 9.3 66.9 18.1 10.5 12.3 12.4 12.5 25.8 19.4 12.8 17.6 8.6 14.3 14.7 14.6 18.9 18.7 18.2 15.6 12.4 14.6 28.4 20.2 12.0 14.5 17.0 95.1 10.3 12.9 15.9 31.6 18.9 8.2 19.9 10.0 20.1 11.5 21.9 98.9 13.2 8.2 13.0 7.0 17.2 13.7 16.3 3.6 72.1 19.9 22.5 19.6 71.9 92.3 10.6 9.6 25.9 22.0 6.5 16.8 43.6 65.4 28.3 19.7 20.2 14.7 24.7 25.5 22.3 10.1 13.1 25.4 14.7 17.4 10.7 MSL2 "FLJ10546, KIAA1585, msl-2, MSL2L1, RNF184" ENSG00000174579 "MSL complex subunit 2" Q9HCI7 3 136148917-136197241 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003413 Uncertain Approved Nucleoplasm,Cytosol NA No "Cluster 32: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "HPA003413: AB_1848659" "unprognostic (9.86e-2)" "prognostic favorable (4.80e-4)" "unprognostic (1.30e-1)" "unprognostic (2.32e-1)" "unprognostic (4.41e-2)" "unprognostic (8.11e-3)" "unprognostic (1.37e-2)" "unprognostic (4.62e-2)" "unprognostic (7.01e-2)" "unprognostic (1.36e-1)" "unprognostic (1.71e-1)" "unprognostic (2.54e-2)" "unprognostic (2.23e-1)" "unprognostic (5.79e-3)" "unprognostic (4.54e-2)" "unprognostic (3.52e-2)" "unprognostic (1.76e-3)" 11.9 9.4 6.0 21.3 8.7 57.9 13.8 18.8 8.6 14.7 5.0 12.9 13.3 15.2 9.2 12.7 15.5 12.8 9.5 6.3 7.3 11.3 14.1 14.5 33.1 6.5 7.2 20.9 11.5 15.3 8.0 13.1 9.2 12.0 12.7 14.8 13.0 11.5 12.6 11.4 14.8 12.1 6.0 25.8 14.7 17.4 7.2 60.3 17.0 17.2 31.7 13.3 10.1 12.1 26.5 7.5 20.8 23.2 14.4 15.6 33.1 16.1 16.0 14.9 14.9 19.4 15.0 52.1 21.2 14.3 17.0 20.4 24.6 16.2 23.5 25.3 11.9 59.6 19.8 11.0 14.8 51.7 26.1 12.6 17.7 11.7 34.0 14.2 15.1 48.1 22.0 47.7 12.5 15.8 93.8 26.7 25.3 14.7 13.1 40.5 33.5 35.3 7.1 21.2 25.2 16.8 37.7 16.1 26.5 16.2 14.7 28.5 20.6 19.0 15.0 17.4 15.1 47.5 28.0 78.7 15.9 20.2 13.2 5.1 2.5 4.1 5.1 2.9 6.2 3.1 4.7 6.0 2.7 5.4 9.6 6.4 5.9 5.1 2.2 1.5 3.9 4.2 6.0 8.7 18.8 8.6 6.3 7.3 6.5 7.2 9.2 6.0 7.2 12.1 15.0 19.2 11.2 18.9 30.4 28.0 15.6 5.6 23.3 12.9 15.8 9.5 15.2 8.6 7.0 12.9 4.2 8.9 47.1 9.3 3.9 5.1 4.1 9.6 15.3 13.9 18.0 23.1 28.0 5.6 6.3 14.7 9.2 12.9 7.0 12.6 16.8 23.4 8.5 16.8 31.6 14.1 2.0 24.2 25.4 3.7 9.3 18.9 21.4 37.5 21.4 8.0 30.9 39.2 55.1 6.4 5.6 8.6 27.8 14.5 7.7 7.4 5.7 9.7 6.6 18.6 12.3 16.0 12.5 22.8 26.7 4.8 36.2 8.5 12.2 14.0 MSLN "CAK1, MPF" ENSG00000102854 Mesothelin Q13421 16 760734-768865 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 93.4;fallopian tube: 278.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Alveolar cells type 2: 85.6;Club cells: 121.9;Glandular and luminal cells: 57.1;Paneth cells: 214.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 343.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.9" "Group enriched" "Detected in many" 39 "dendritic cells: 5.9;monocytes: 1.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 513.4;EFO-21: 77.4;HeLa: 173.4;hTCEpi: 111.5;OE19: 96.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "spinal cord: 1.7" "CAB002216, HPA017172" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "CAB002216: AB_563874, HPA017172: AB_1853819" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (3.95e-2)" "unprognostic (2.46e-1)" "unprognostic (9.47e-2)" "unprognostic (8.57e-2)" "unprognostic (4.69e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.63e-1)" "prognostic favorable (5.91e-4)" "unprognostic (2.00e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-2)" "unprognostic (3.35e-2)" 93.4 0.2 0.7 1.1 1.0 3.2 0.5 0.6 1.5 15.9 0.3 8.9 7.1 6.2 24.1 7.1 278.2 16.4 8.4 0.7 0.8 6.5 0.2 71.8 0.2 1.9 1.2 3.7 0.9 0.1 0.7 2.7 1.3 3.8 4.0 0.7 39.3 9.9 0.0 1.4 2.9 3.4 1.0 0.4 13.0 1.1 1.2 0.8 0.2 0.0 27.2 2.9 2.9 1.0 0.4 2.1 0.0 1.0 0.0 0.0 2.3 0.3 7.7 8.7 2.0 7.4 513.4 0.0 77.4 0.7 0.1 1.3 0.0 0.7 0.7 0.2 0.3 0.0 173.4 5.9 4.4 0.2 0.1 0.0 111.5 0.0 2.0 7.8 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.1 0.6 96.4 0.8 0.2 0.2 0.6 2.4 0.1 0.1 0.0 29.7 0.1 0.0 0.1 0.7 0.0 0.0 0.4 12.1 0.1 0.0 0.3 0.3 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.3 0.7 1.0 0.6 1.5 0.7 0.8 1.9 1.2 1.3 1.0 1.2 1.0 0.0 189.1 85.6 0.0 0.0 0.3 3.0 49.0 0.0 1.4 0.3 0.3 1.6 52.9 121.9 25.8 0.0 0.2 0.0 4.1 0.0 9.3 1.6 35.8 3.3 0.7 3.0 0.0 0.0 0.9 0.0 4.6 0.0 57.1 0.0 0.0 0.4 0.1 2.9 0.0 0.0 1.6 22.4 1.0 1.9 7.4 4.7 3.7 1.8 1.0 4.4 0.0 0.0 0.0 0.0 33.0 214.4 0.0 1.4 3.3 1.7 0.1 54.2 0.6 0.0 0.0 2.8 0.6 0.7 0.5 0.1 0.1 1.3 0.0 3.1 50.8 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.3;stomach 1: 42.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Distal enterocytes: 53.9;Gastric mucus-secreting cells: 108.6;Intestinal goblet cells: 25.7;Pancreatic endocrine cells: 31.2;Paneth cells: 30.3;Proximal enterocytes: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 39.3;CAPAN-2: 98.8;HaCaT: 56.3;HBEC3-KT: 59.4;hTCEpi: 83.4;RT4: 67.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" 5.1 0.3 1.1 5.1 1.1 0.2 3.8 1.1 1.7 5.7 1.3 26.5 25.2 1.3 1.2 17.5 1.7 11.4 3.2 1.1 0.9 3.4 1.1 9.5 2.5 0.9 0.8 1.0 5.8 0.1 2.7 0.8 0.9 4.7 20.1 0.2 5.4 1.0 1.3 62.3 23.9 2.0 0.8 1.6 42.6 8.4 0.9 8.8 3.4 0.7 5.6 9.2 11.5 1.0 39.3 14.4 0.1 0.6 0.0 0.0 2.2 0.5 0.1 0.0 0.0 4.1 98.8 1.7 8.8 0.5 0.1 56.3 0.0 59.4 0.0 0.9 1.0 0.1 25.9 0.9 0.9 0.0 1.2 0.3 83.4 0.2 11.7 0.2 0.1 0.2 0.8 0.3 0.0 5.1 0.1 0.1 0.3 33.1 34.6 2.9 0.0 1.1 35.8 67.9 1.0 0.1 11.5 22.6 0.2 0.1 17.7 0.9 0.3 0.0 0.3 0.3 0.1 0.5 0.2 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 1.1 1.1 1.7 1.1 0.9 0.9 0.8 0.9 0.8 0.9 1.0 1.6 25.6 10.3 0.7 1.0 8.8 2.2 14.2 6.8 0.0 2.8 2.5 1.0 0.0 10.6 0.0 0.0 0.1 0.2 53.9 0.0 6.4 15.4 2.9 0.8 0.6 4.2 0.0 1.1 10.0 0.4 0.8 108.6 5.3 0.0 0.1 0.0 0.0 0.1 0.0 1.1 25.7 2.0 0.0 1.4 10.5 0.3 0.5 0.0 1.0 0.6 0.0 1.0 2.0 0.1 31.2 30.3 0.0 0.5 2.2 27.6 0.1 7.6 0.0 0.0 0.5 0.9 1.3 1.5 3.2 4.7 0.0 0.5 0.0 20.1 6.2 MT1M "MT1, MT1K" ENSG00000205364 "Metallothionein 1M" Q8N339 16 56632659-56633981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 398.9;liver: 562.4" "Cell type enhanced" "Detected in many" "Adipocytes: 1333.5;Distal enterocytes: 906.4;Glandular and luminal cells: 1180.5;Hepatocytes: 1549.5;Paneth cells: 1204.8;Proximal enterocytes: 933.2;Smooth muscle cells: 680.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RPTEC TERT1: 181.8" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.83e-2)" "unprognostic (2.49e-1)" "unprognostic (2.10e-2)" "unprognostic (3.10e-2)" "unprognostic (4.19e-3)" "unprognostic (7.73e-2)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.13e-4)" "unprognostic (4.67e-2)" "unprognostic (3.10e-1)" "unprognostic (3.55e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-2)" "unprognostic (4.71e-2)" 398.9 27.7 214.3 32.8 233.5 0.1 145.6 240.4 316.0 31.2 183.0 134.0 21.2 14.8 4.1 83.4 95.4 42.6 36.6 207.3 219.5 47.6 562.4 116.5 4.5 225.3 226.8 16.1 145.8 2.6 10.4 2.7 232.6 57.5 140.9 24.7 31.5 6.7 48.2 44.6 113.6 37.3 217.6 7.7 98.5 3.9 246.4 5.2 64.3 4.0 2.5 33.4 26.1 213.6 0.0 0.0 0.0 0.0 39.1 27.3 0.5 1.2 9.9 1.2 2.4 0.4 0.6 0.0 7.9 6.3 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.2 0.1 3.1 0.0 14.8 0.0 23.7 0.0 0.0 0.0 0.0 19.6 0.0 0.1 0.2 13.4 0.0 1.3 0.0 0.1 0.2 181.8 0.0 0.2 0.5 0.0 0.0 0.0 1.7 0.0 2.7 5.5 0.1 0.0 1.8 0.0 0.1 0.0 0.2 4.7 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 214.3 233.5 240.4 316.0 207.3 219.5 225.3 226.8 232.6 217.6 246.4 213.6 1333.5 12.8 7.2 49.6 9.3 27.5 19.0 3.1 27.9 0.0 13.7 52.7 7.9 121.5 6.0 14.7 0.0 0.3 4.9 906.4 37.2 58.9 0.1 413.6 114.7 141.3 32.7 131.0 0.1 117.0 70.5 308.1 25.5 1180.5 15.9 11.9 82.8 1549.5 1.7 0.0 0.1 397.5 0.0 65.9 39.9 1.5 47.8 35.2 88.9 5.6 24.3 0.0 0.0 6.0 0.3 64.1 1204.8 12.0 29.4 152.4 933.2 258.6 5.2 0.0 78.9 587.1 680.1 0.0 0.5 4.7 20.2 1.0 15.5 1.2 559.6 7.9 MTARC1 "FLJ22390, MARC1, MOSC1" ENSG00000186205 "Mitochondrial amidoxime reducing component 1" Q5VT66 1 220786913-220819659 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 192.3;breast: 86.2;liver: 84.5" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 109.8;Extravillous trophoblasts: 47.9;Syncytiotrophoblasts: 75.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 30.2;classical monocyte: 33.6;eosinophil: 12.3;neutrophil: 42.8" "Group enriched" "Detected in many" 31 "granulocytes: 42.8;monocytes: 33.6" "Cell line enhanced" "Detected in many" "BEWO: 126.5;HeLa: 56.2;Hep G2: 67.6;NTERA-2: 57.8;OE19: 49.4" HPA028702 Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA028702: AB_10601135" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (2.16e-2)" "unprognostic (5.04e-2)" "unprognostic (2.90e-1)" "unprognostic (2.31e-1)" "unprognostic (3.71e-3)" "unprognostic (1.39e-1)" "unprognostic (7.51e-2)" "unprognostic (7.71e-3)" "unprognostic (3.71e-1)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.85e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" 192.3 7.4 9.4 6.8 10.5 17.9 86.2 9.8 13.2 7.9 7.9 18.9 7.6 2.8 14.0 7.6 6.2 4.1 8.4 10.0 11.7 10.2 84.5 9.3 2.8 10.1 11.8 5.5 9.6 5.4 7.0 16.0 9.6 36.2 17.3 5.7 27.2 13.5 11.0 3.6 9.7 4.0 9.1 10.2 9.3 1.4 14.3 1.6 53.5 9.2 2.1 8.8 5.0 8.5 15.0 7.8 5.9 0.2 1.3 0.3 126.5 1.4 1.2 0.8 1.5 45.4 1.0 0.1 5.3 1.6 0.1 0.1 28.3 2.9 2.1 0.2 25.7 0.1 56.2 67.6 2.7 0.3 0.5 4.5 1.3 0.2 0.0 0.2 1.1 0.1 4.3 0.3 1.1 14.7 0.1 31.9 57.8 49.4 23.8 0.1 0.0 0.3 7.1 17.4 16.4 36.1 8.1 11.4 0.2 16.4 38.5 34.7 0.4 0.1 12.6 0.1 0.1 0.2 0.1 0.1 0.2 0.0 1.1 30.2 33.6 12.3 0.1 2.5 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.0 42.8 0.0 1.3 0.3 0.0 9.2 9.4 10.5 9.8 13.2 10.0 11.7 10.1 11.8 9.6 9.1 14.3 8.5 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 47.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 MTCL1 "CCDC165, KIAA0802, SOGA2" ENSG00000168502 "Microtubule crosslinking factor 1" Q9Y4B5 18 8705661-8832778 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 90.1;intestine: 28.1;retina: 34.0" "Cell type enhanced" "Detected in many" "Early spermatids: 26.0;Excitatory neurons: 86.4;Granulosa cells: 28.9;Inhibitory neurons: 80.4;Oligodendrocyte precursor cells: 24.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "cerebellum: 90.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 32.0" HPA046245 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046245: AB_10962580" "unprognostic (2.64e-1)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.35e-1)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-1)" "unprognostic (4.41e-4)" "unprognostic (1.30e-2)" "unprognostic (7.19e-2)" "unprognostic (9.95e-2)" "unprognostic (2.51e-1)" "unprognostic (1.79e-2)" "prognostic unfavorable (5.19e-4)" "unprognostic (2.82e-1)" "unprognostic (3.67e-1)" "unprognostic (7.17e-3)" "unprognostic (1.08e-2)" 1.6 0.9 0.0 2.5 0.6 0.5 1.4 90.1 10.1 4.7 0.0 28.1 1.8 2.3 0.7 2.7 1.0 8.1 2.9 0.7 0.5 2.5 1.3 1.2 0.8 4.9 2.6 1.1 3.7 2.8 5.6 2.3 7.3 1.7 1.7 34.0 1.4 3.0 2.1 2.5 4.3 5.2 0.9 0.6 8.9 8.0 0.0 3.7 0.4 1.1 0.5 9.4 4.6 6.3 16.8 35.3 17.4 10.2 7.6 14.1 0.7 22.9 16.9 18.6 13.4 10.4 5.8 10.5 12.8 16.1 13.9 2.5 5.5 9.4 8.5 2.1 4.5 5.1 10.1 9.4 10.9 0.1 7.3 8.3 6.8 10.5 7.2 12.1 14.8 8.8 1.1 17.8 8.7 5.0 0.7 2.5 7.9 40.2 15.2 14.0 12.5 3.8 26.9 29.9 39.3 8.8 10.5 3.0 2.7 14.3 1.0 0.6 28.2 33.8 17.6 27.4 23.8 3.4 2.8 5.1 8.4 0.6 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 90.1 10.1 0.7 0.5 4.9 2.6 7.3 0.9 0.0 6.3 0.4 0.0 1.1 9.4 1.3 0.0 2.8 0.0 4.6 0.0 1.5 1.9 6.5 8.6 0.6 1.8 0.0 5.0 1.8 1.8 1.9 5.6 26.0 2.8 2.3 2.1 1.2 4.6 86.4 3.5 0.4 1.5 5.6 7.8 2.5 28.9 4.6 1.0 0.6 0.0 80.4 1.5 0.0 0.6 0.0 8.8 1.2 0.3 0.0 8.4 0.1 0.0 0.0 24.1 18.3 8.6 0.2 0.4 1.9 4.6 0.2 1.9 0.0 0.0 0.0 0.8 1.9 0.9 5.2 3.0 0.0 1.0 0.4 1.3 1.2 1.3 MTMR1 ENSG00000063601 "Myotubularin related protein 1" Q13613 X 150692971-150765108 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 79.3;Excitatory neurons: 61.2;Inhibitory neurons: 58.1;Oligodendrocyte precursor cells: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 104.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018502, HPA075953" Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA018502: AB_1854185, HPA075953: " "unprognostic (2.37e-2)" "unprognostic (1.64e-3)" "unprognostic (2.07e-1)" "unprognostic (1.05e-2)" "unprognostic (4.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (4.35e-2)" "unprognostic (3.16e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-2)" "unprognostic (1.67e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.19e-1)" "unprognostic (8.40e-2)" 6.7 7.2 11.3 11.1 13.0 11.9 12.5 11.7 13.0 9.3 7.1 10.2 9.0 7.9 7.1 20.6 9.7 7.2 12.2 17.3 10.8 8.3 9.0 9.5 21.8 7.5 10.0 8.5 10.0 17.9 9.2 14.2 7.6 10.9 9.4 22.1 12.4 10.9 22.9 21.4 10.4 7.3 9.2 14.3 10.7 8.0 11.9 31.3 10.0 16.0 25.5 12.6 13.5 8.7 32.3 20.3 21.5 17.7 4.9 5.7 28.8 28.1 36.0 28.0 39.4 19.8 24.9 70.2 40.1 22.9 27.1 28.4 43.9 40.8 43.2 28.4 26.3 4.4 31.6 8.5 14.5 20.7 14.6 15.6 27.7 30.8 0.4 26.8 17.1 22.9 13.8 17.5 20.3 27.7 30.6 5.3 9.9 35.9 30.3 16.0 34.1 31.2 22.0 36.4 31.9 19.9 10.7 23.7 8.8 17.0 30.3 11.8 21.7 18.3 14.6 2.3 42.1 22.2 24.6 104.8 3.7 13.3 14.4 0.0 0.5 5.0 2.1 0.9 1.5 1.7 2.3 1.9 1.4 1.9 2.0 2.8 1.5 3.9 0.9 5.0 3.2 1.2 11.3 13.0 11.7 13.0 17.3 10.8 7.5 10.0 7.6 9.2 11.9 8.7 3.7 16.0 6.5 79.3 11.4 11.2 11.0 8.0 6.8 0.0 7.8 5.5 8.2 2.8 7.5 5.5 0.0 10.1 19.3 4.6 0.0 5.9 0.0 10.0 3.7 3.6 9.6 6.5 61.2 6.6 7.3 4.5 7.7 9.2 1.3 4.8 2.9 8.0 4.6 0.0 58.1 5.5 8.2 9.4 8.8 1.7 5.6 4.8 3.6 30.0 6.2 0.0 8.2 54.8 22.6 10.6 8.6 5.3 7.9 11.0 3.8 3.1 8.4 0.0 6.6 6.7 3.9 2.5 3.0 10.3 16.8 10.4 8.8 5.9 5.9 12.5 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "salivary gland: 2621.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 443.2;Distal enterocytes: 158.4;Intestinal goblet cells: 210.1;Undifferentiated cells: 183.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "OE19: 113.9;PC-3: 120.0" "Not detected" "Not detected" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" NA NA 1300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB009396: AB_2282256, HPA008246: AB_1854203" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (2.76e-3)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.89e-2)" "unprognostic (7.80e-3)" "unprognostic (3.75e-1)" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (8.95e-2)" "unprognostic (2.57e-7)" "unprognostic (2.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" 0.1 0.7 0.2 2.0 0.1 0.0 1.3 0.0 0.4 229.4 0.0 58.0 0.1 0.3 0.0 101.0 1.1 221.3 0.1 0.0 0.0 0.1 2.4 7.5 0.0 0.1 0.0 0.1 9.8 0.0 0.4 0.0 0.0 0.6 17.1 0.0 2621.9 0.0 0.3 0.4 2.6 0.6 0.0 0.0 6.9 0.3 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.2 0.0 113.9 120.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 2.3 0.0 0.0 6.7 0.6 0.0 6.4 4.3 12.4 443.2 64.0 0.0 0.0 0.1 0.0 158.4 0.0 0.9 0.0 1.4 0.8 0.9 24.5 0.0 0.1 0.0 0.1 1.1 12.8 7.2 4.5 0.0 0.0 1.2 0.2 0.0 0.0 210.1 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 53.4 0.0 1.4 1.3 0.1 0.2 24.5 0.0 0.0 0.0 3.0 0.0 0.5 1.6 0.0 0.1 0.7 0.1 183.1 1.1 MVK "LRBP, MK" ENSG00000110921 "Mevalonate kinase" Q03426 12 109573255-109598125 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.1" "Cell type enhanced" "Detected in all" "Early spermatids: 60.5;Horizontal cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016961, HPA044110" Approved Supported Vesicles,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Cytosol" "HPA016961: AB_1854220, HPA044110: " "unprognostic (3.10e-1)" "unprognostic (2.27e-2)" "unprognostic (1.85e-1)" "unprognostic (4.43e-2)" "unprognostic (3.66e-2)" "unprognostic (2.08e-2)" "unprognostic (4.30e-2)" "unprognostic (8.98e-2)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (8.23e-2)" "unprognostic (1.30e-1)" "unprognostic (6.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (3.88e-1)" "unprognostic (3.28e-1)" 7.9 29.8 12.7 6.1 13.7 8.3 14.7 16.7 15.0 14.5 9.6 11.2 13.9 7.3 10.2 45.5 6.3 5.3 9.4 11.1 13.2 32.1 69.1 11.4 6.9 36.1 15.5 10.7 10.0 11.5 11.6 5.4 38.6 12.3 8.6 7.3 13.7 7.0 12.1 33.3 9.8 5.0 15.3 6.7 11.8 28.5 15.3 4.2 15.1 8.8 9.1 9.5 20.1 24.4 30.1 25.0 29.9 13.7 11.2 27.3 14.4 9.5 21.7 30.0 32.8 31.4 33.8 17.7 7.8 11.7 48.1 36.0 31.6 50.0 13.2 19.0 18.1 9.9 15.7 53.7 31.5 11.1 13.0 27.2 42.1 48.8 13.6 12.6 20.9 19.0 18.7 17.4 13.6 34.5 12.0 34.6 22.6 14.9 32.3 10.5 22.1 37.0 67.4 40.9 25.1 18.7 19.8 58.7 14.0 11.0 59.7 21.1 14.1 13.2 14.5 12.0 12.8 13.3 20.6 28.2 16.1 29.2 16.6 1.0 6.9 4.0 12.6 6.5 11.3 9.4 7.4 12.4 8.6 14.1 10.9 8.3 1.6 11.0 4.6 7.0 7.6 6.4 12.7 13.7 16.7 15.0 11.1 13.2 36.1 15.5 38.6 15.3 15.3 24.4 6.1 12.8 12.4 6.8 8.3 4.7 5.2 39.7 4.6 12.4 13.1 11.0 5.7 11.5 25.8 14.7 18.8 33.0 7.3 10.4 21.5 15.6 60.5 5.8 2.3 7.1 9.0 4.8 5.1 18.1 15.3 6.8 9.7 5.1 1.3 14.7 6.4 32.7 15.6 62.2 5.2 7.8 10.2 3.4 2.2 42.5 8.1 4.8 7.2 3.7 10.3 10.6 10.3 4.0 15.3 13.2 3.2 7.2 4.1 5.5 16.4 52.4 13.5 12.2 6.6 4.0 8.2 33.9 16.8 12.0 8.5 47.9 6.1 44.8 11.1 4.6 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MYBL2 "B-MYB, BMYB" ENSG00000101057 "MYB proto-oncogene like 2" P10244 20 43667019-43716495 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;lymphoid tissue: 55.5" "Cell type enhanced" "Detected in many" "B-cells: 33.0;dendritic cells: 32.6;Erythroid cells: 82.3;Extravillous trophoblasts: 32.3;Plasma cells: 139.6;Spermatogonia: 33.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 295.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 91.5" "Lineage enriched" "Detected in many" 34 "dendritic cells: 91.5" "Cell line enhanced" "Detected in many" "MCF7: 763.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017114, HPA030530, HPA055416" Uncertain Supported Nucleoplasm,Cytosol Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB017114: , HPA030530: AB_2673515, HPA055416: AB_2682811" "unprognostic (9.75e-3)" "unprognostic (1.29e-2)" "unprognostic (3.20e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (2.35e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.66e-3)" "unprognostic (9.23e-3)" "unprognostic (1.78e-1)" "unprognostic (2.38e-3)" "unprognostic (1.32e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-1)" "unprognostic (2.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" 1.6 0.6 0.1 24.2 0.1 91.8 1.6 0.1 0.2 1.1 0.2 8.6 7.0 1.4 0.1 10.1 0.4 1.0 0.4 0.1 0.1 0.6 1.1 1.8 55.5 0.1 0.1 0.3 11.2 0.1 0.2 5.7 0.1 0.5 6.9 0.0 1.6 0.2 0.1 4.2 7.8 2.1 0.1 27.8 6.1 15.6 0.4 33.3 0.5 0.0 53.5 3.5 2.5 0.1 195.8 121.8 105.4 109.6 1.0 3.5 136.2 87.0 29.0 265.6 194.6 600.2 118.8 393.6 49.2 37.8 55.8 116.1 192.1 59.6 98.8 74.2 124.1 183.2 118.7 164.2 0.2 168.6 121.7 2.4 5.1 101.6 22.9 5.9 72.2 189.6 188.1 470.3 23.8 763.7 346.0 236.3 121.8 155.4 105.4 237.3 216.3 222.1 49.6 39.7 96.7 140.6 255.6 253.3 26.1 110.4 167.2 183.1 34.0 16.3 264.3 118.3 151.5 162.1 363.8 606.5 34.2 142.3 103.9 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.2 0.0 91.5 1.3 0.8 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.2 0.0 0.0 0.0 33.0 4.2 0.8 0.8 0.0 0.0 2.5 3.4 2.0 1.5 0.1 0.0 0.0 14.4 32.6 3.4 0.0 0.4 5.9 0.9 1.3 1.8 0.0 82.3 0.4 0.9 32.3 4.8 10.2 2.9 0.0 18.9 0.7 1.4 13.5 0.0 0.3 5.1 0.0 2.4 2.6 14.1 0.0 3.2 1.8 0.0 0.0 0.0 1.0 0.0 0.5 0.7 1.1 0.0 139.6 0.3 0.5 0.0 0.0 0.0 0.0 0.1 3.9 7.0 33.6 8.2 2.4 3.7 3.0 1.2 8.6 2.4 MYCN "bHLHe37, MYCNOT, N-myc, NMYC" ENSG00000134323 "MYCN proto-oncogene, bHLH transcription factor" P04198 2 15940550-15947007 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 9.5" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 84.2;Granulosa cells: 26.4" "Cancer enriched" "Detected in many" 5 "testis cancer: 45.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 44.1;BEWO: 239.1;HMC-1: 57.3;NTERA-2: 91.3;RH-30: 63.3;SuSa: 40.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057420 Approved Nucleoplasm,Nucleoli NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "HPA057420: AB_2683434" "unprognostic (8.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.07e-2)" "unprognostic (4.11e-1)" "unprognostic (2.46e-2)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.09e-2)" "unprognostic (2.09e-1)" "unprognostic (1.12e-3)" "unprognostic (8.89e-2)" "unprognostic (2.47e-1)" "unprognostic (4.90e-2)" "unprognostic (1.23e-1)" 0.4 0.8 3.5 0.6 3.5 0.9 0.4 3.1 3.9 1.5 0.8 0.6 1.6 0.9 0.1 0.7 0.5 0.3 1.2 3.4 3.0 3.3 0.8 0.7 1.6 4.4 3.9 5.1 0.2 0.1 0.3 9.5 3.7 0.1 0.5 1.0 4.7 0.2 0.4 1.4 0.9 0.3 3.3 0.3 4.6 3.6 3.5 2.9 2.9 0.7 1.2 0.5 0.4 5.9 0.0 0.0 44.1 0.0 0.0 0.0 239.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 4.2 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 16.8 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.8 0.4 0.2 91.3 2.1 0.0 0.0 63.3 12.8 0.0 3.1 1.0 16.0 0.0 0.1 0.0 40.9 0.1 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.5 3.1 3.9 3.4 3.0 4.4 3.9 3.7 3.3 3.5 5.9 0.8 0.0 0.0 0.7 0.0 0.5 0.1 0.0 0.0 2.6 0.1 0.9 0.7 0.0 0.0 0.0 0.0 5.6 0.0 0.2 0.0 0.0 1.2 0.5 0.1 2.7 0.0 4.2 2.0 0.0 84.2 1.0 2.6 0.8 0.0 26.4 0.0 0.6 2.4 0.0 4.2 0.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.1 1.0 0.0 10.1 7.5 0.3 1.1 0.4 0.0 0.0 0.4 3.2 0.0 0.2 0.0 4.2 0.7 1.3 3.7 0.3 0.0 11.5 0.0 9.4 0.3 0.0 MYH14 "DFNA4, FLJ13881, KIAA2034, MHC16, MYH17" ENSG00000105357 "Myosin heavy chain 14" Q7Z406 19 50188186-50310542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 191.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 487.2;Paneth cells: 306.4;Proximal enterocytes: 376.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 48.6;CAPAN-2: 59.4;HaCaT: 119.0;MCF7: 59.0;OE19: 61.7;RT4: 147.8;SK-BR-3: 51.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062391, HPA067889, HPA070260" Enhanced Approved Nucleoplasm NA NA 9600000 "Cluster 80: Striated muscle - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA062391: AB_2684748, HPA067889: AB_2685917, HPA070260: AB_2686243" "unprognostic (2.52e-1)" "unprognostic (5.81e-2)" "unprognostic (9.63e-2)" "unprognostic (3.73e-3)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.71e-1)" "unprognostic (3.48e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "prognostic favorable (3.97e-8)" "prognostic favorable (7.83e-4)" "unprognostic (8.50e-2)" "unprognostic (3.12e-1)" "unprognostic (2.77e-1)" 12.6 1.0 24.1 7.0 35.0 0.0 8.8 38.2 23.3 13.3 22.0 64.5 83.8 1.5 0.2 63.7 15.4 3.6 41.3 20.0 30.9 10.2 25.4 24.4 0.1 38.7 35.6 0.4 17.3 16.7 18.5 0.4 35.7 8.8 19.5 5.1 44.0 5.7 191.3 87.7 76.7 1.3 29.5 0.1 45.5 2.6 34.4 1.5 33.2 35.1 6.1 11.0 31.8 37.4 48.6 5.0 0.0 25.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 33.1 59.4 0.2 30.1 0.0 3.7 119.0 0.1 0.0 0.0 0.1 8.7 0.0 0.0 25.7 0.0 0.0 17.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 59.0 0.0 0.3 0.8 61.7 0.7 0.1 29.4 0.7 0.0 147.8 0.1 0.2 2.9 51.8 0.0 0.2 9.7 1.9 0.0 0.1 11.7 0.2 0.1 0.9 11.2 0.3 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 35.0 38.2 23.3 20.0 30.9 38.7 35.6 35.7 29.5 34.4 37.4 0.1 80.1 36.5 23.5 2.8 3.3 18.7 29.3 0.0 3.7 17.9 9.3 21.8 44.3 50.9 57.0 2.1 0.1 0.3 487.2 0.0 53.2 0.9 58.1 6.0 1.2 51.6 0.0 10.9 27.2 0.1 1.1 85.1 70.7 14.7 0.0 2.9 45.8 0.1 16.8 21.7 109.4 22.4 0.8 1.6 0.8 0.3 1.3 5.4 2.8 0.0 19.7 0.0 23.6 27.5 67.5 306.4 0.0 0.3 30.8 376.1 7.6 80.6 11.5 0.0 17.7 3.5 0.5 4.6 30.8 21.0 0.0 2.0 0.0 122.8 86.2 MYL9 "LC20, MLC2, MRLC1, MYRL2" ENSG00000101335 "Myosin light chain 9" P24844 20 36541497-36551447 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 8015.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 860.2;Cardiomyocytes: 1856.1;Peritubular cells: 1891.9;Sertoli cells: 2143.1;Smooth muscle cells: 2525.7;Theca cells: 881.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 783.3;BJ: 1047.3;fHDF/TERT166: 844.3;hTERT-RPE1: 645.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 76.1" "HPA039262, HPA045244, HPA059197" Supported NA NA 34000000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (1.15e-1)" "unprognostic (5.05e-2)" "unprognostic (2.67e-3)" "unprognostic (5.38e-2)" "unprognostic (7.17e-2)" "unprognostic (5.06e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (9.06e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (7.92e-7)" "unprognostic (1.90e-2)" "unprognostic (8.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.92e-2)" 944.6 948.6 61.6 347.0 76.7 5.2 649.5 63.3 132.2 1083.0 104.6 8015.9 270.5 2897.3 238.2 999.8 1643.3 364.3 2294.5 61.4 63.1 352.2 116.6 617.9 56.4 66.3 66.3 717.2 82.0 45.4 91.2 160.3 66.1 2347.4 345.8 22.8 200.7 2248.7 164.3 289.2 1287.7 2107.8 62.0 274.3 1946.4 260.7 66.5 27.4 431.7 111.4 23.2 4176.1 943.6 63.3 79.4 1.3 60.3 1.2 783.3 298.6 264.5 1047.3 450.9 541.3 349.9 612.3 9.1 0.2 535.6 844.3 120.6 29.4 0.2 2.4 125.7 0.9 0.2 16.7 114.4 57.3 500.4 0.4 17.7 420.8 54.4 359.9 1.6 645.9 19.2 0.0 2.4 28.0 461.7 0.2 0.3 7.8 24.0 16.1 5.6 0.4 0.0 5.8 4.6 5.8 0.6 4.1 11.1 26.6 0.6 257.5 232.9 15.6 137.0 510.9 220.1 75.5 1.0 0.8 4.0 2.3 194.3 0.8 0.6 0.0 0.1 2.2 0.0 0.0 0.0 0.9 0.0 0.1 0.3 0.2 0.0 0.0 1.9 0.2 0.0 0.4 0.0 7.2 61.6 76.7 63.3 132.2 61.4 63.1 66.3 66.3 66.1 62.0 66.5 63.3 325.3 394.2 52.3 0.0 6.6 60.7 320.2 167.1 21.6 1.4 36.8 860.2 1856.1 24.3 50.8 90.1 0.0 37.0 6.3 0.1 27.4 310.3 9.3 13.1 419.9 179.7 0.0 5.7 0.2 116.0 78.3 410.4 10.2 9.3 15.2 234.3 169.9 2.7 32.0 1.7 0.1 1.2 14.2 5.0 76.6 55.4 331.8 111.7 72.9 30.9 19.4 230.4 6.2 0.0 0.5 47.9 2.5 1891.9 6.4 156.9 105.5 42.1 31.8 6.1 2143.1 65.9 2525.7 16.3 9.5 6.5 53.4 26.8 14.7 881.1 2.0 61.9 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1700.3;smooth muscle: 2137.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 728.5;Hepatocytes: 208.7;Peritubular cells: 690.5;Sertoli cells: 276.1;Smooth muscle cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 200.0;BJ hTERT+: 298.2;fHDF/TERT166: 260.2;hTERT-RPE1: 202.7;RPTEC TERT1: 291.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 143.6 57.4 37.6 188.7 64.8 3.3 163.4 72.1 42.4 281.3 14.1 551.5 110.9 669.2 232.9 420.6 289.8 250.4 33.6 33.6 46.7 64.4 67.2 85.2 33.6 104.6 64.8 95.9 15.3 11.6 2.6 70.2 99.3 907.6 299.1 13.6 140.1 1700.3 10.0 20.1 125.1 2137.7 55.6 89.5 122.7 50.5 52.2 8.0 22.2 14.9 19.1 505.7 84.8 112.1 14.4 38.4 10.8 7.8 10.8 1.9 4.7 200.0 298.2 137.3 92.1 8.1 7.4 0.6 42.5 260.2 67.0 4.8 5.2 1.8 149.0 0.2 0.7 102.4 0.9 28.9 56.1 0.6 9.8 36.9 3.5 24.4 34.4 202.7 8.9 1.3 1.2 0.5 90.9 1.7 0.2 2.5 12.0 0.5 5.1 13.5 6.8 36.7 291.9 8.5 1.4 6.4 21.8 1.9 3.1 25.0 1.0 0.3 33.4 39.5 13.9 10.3 30.7 3.4 4.2 0.3 104.0 1.0 9.6 7.4 1.6 0.4 0.1 0.2 0.0 0.2 0.0 0.0 3.5 0.1 0.2 0.1 5.0 0.0 0.0 3.3 0.2 20.9 37.6 64.8 72.1 42.4 33.6 46.7 104.6 64.8 99.3 55.6 52.2 112.1 45.9 16.0 38.3 43.4 2.5 20.5 27.2 24.8 1.2 2.9 19.9 728.5 25.2 37.1 5.7 27.6 125.1 0.8 3.5 88.1 3.9 6.0 40.7 45.9 46.6 56.9 11.4 3.2 25.2 3.9 0.8 40.1 3.1 54.4 2.5 3.2 45.3 208.7 4.9 3.3 3.4 3.9 8.2 7.9 37.0 33.8 104.7 20.8 19.6 8.4 1.2 4.7 0.0 5.5 37.0 4.0 18.7 690.5 3.3 8.6 14.2 17.2 17.6 19.9 276.1 5.6 448.7 4.7 4.6 1.3 20.2 2.5 3.2 4.5 4.2 3.7 MYO15B MYO15BP ENSG00000266714 "Myosin XVB" Q96JP2 17 75588058-75626849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 179.2" "Group enriched" "Detected in many" 4 "Distal enterocytes: 275.4;Paneth cells: 294.2;Proximal enterocytes: 127.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A549: 46.4;HEL: 17.7;HMC-1: 24.9;THP-1: 37.7" "Not detected" "Not detected" "HPA022857, HPA023105" Approved Cytosol No No "Cluster 34: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA022857: AB_1848813, HPA023105: AB_1859526" "prognostic favorable (9.34e-4)" "unprognostic (7.55e-2)" "unprognostic (6.99e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (5.59e-4)" "unprognostic (7.29e-3)" "unprognostic (1.48e-1)" "unprognostic (4.97e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-3)" "unprognostic (1.04e-2)" "unprognostic (1.49e-1)" "unprognostic (6.39e-2)" "unprognostic (1.68e-1)" "unprognostic (3.35e-1)" "prognostic favorable (6.90e-5)" 40.0 17.3 34.7 17.3 39.2 57.0 38.1 33.7 45.1 74.7 29.6 53.6 179.2 46.1 7.5 18.6 65.6 25.8 44.4 32.0 34.0 76.0 29.8 55.1 19.2 39.9 36.8 87.1 20.5 4.7 28.9 15.0 40.1 56.5 21.5 9.9 23.6 14.0 13.2 15.9 149.0 9.8 35.5 108.2 25.7 20.9 36.7 17.7 65.8 8.0 7.2 29.0 44.0 46.1 0.6 46.4 0.3 1.2 0.3 0.1 0.7 0.0 0.0 0.0 0.0 5.8 13.6 0.1 1.5 0.0 0.6 0.5 0.0 0.0 0.0 0.6 2.8 17.7 9.5 11.6 1.3 0.0 24.9 0.8 0.8 0.0 0.1 0.8 0.3 7.3 1.2 5.1 0.0 5.0 0.4 7.8 0.7 12.3 11.2 12.7 0.3 2.1 0.3 1.0 1.3 3.2 0.3 0.5 1.5 1.4 3.5 37.7 0.1 0.3 1.2 0.2 0.0 1.7 0.2 0.2 0.7 8.9 0.6 1.3 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.3 0.0 0.4 0.2 0.0 0.1 34.7 39.2 33.7 45.1 32.0 34.0 39.9 36.8 40.1 35.5 36.7 46.1 13.7 0.0 3.3 44.7 8.4 2.4 2.4 2.0 8.0 4.5 4.0 2.7 7.5 11.5 2.4 9.2 16.7 0.1 11.9 275.4 1.9 1.6 0.7 11.6 8.9 14.6 31.7 9.2 1.1 1.5 0.1 7.1 52.0 8.1 14.0 13.6 21.0 2.1 5.5 1.7 1.4 40.3 12.2 10.0 12.6 2.7 5.6 17.5 3.6 42.2 6.9 4.9 12.3 32.6 46.6 8.8 294.2 4.9 1.4 1.9 127.5 14.4 8.0 13.5 6.6 7.1 8.4 3.3 6.8 2.2 3.0 0.1 6.2 4.7 20.1 1.8 MYO18B BK125H2.1 ENSG00000133454 "Myosin XVIIIB" Q8IUG5 22 25742144-26031045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 120.8;skeletal muscle: 262.7;tongue: 55.6" "Group enriched" "Detected in some" 21 "Cardiomyocytes: 95.5;Early spermatids: 61.4;Late spermatids: 37.3;Skeletal myocytes: 32.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.8" "Region enhanced" "Detected in single" "thalamus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 10.6;REH: 15.0;RH-30: 30.5;U-2 OS: 13.2;U-266/70: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA000953 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Centrosome" "HPA000953: AB_1079440" "unprognostic (3.28e-2)" "unprognostic (1.79e-1)" "unprognostic (1.86e-2)" "unprognostic (1.23e-1)" "unprognostic (1.66e-2)" "unprognostic (1.01e-2)" "unprognostic (5.93e-4)" "unprognostic (2.46e-1)" "unprognostic (1.22e-1)" "unprognostic (7.14e-2)" "unprognostic (4.36e-3)" "unprognostic (2.96e-3)" "unprognostic (3.93e-7)" "unprognostic (1.14e-1)" "unprognostic (3.12e-1)" "unprognostic (5.06e-2)" "unprognostic (1.65e-1)" 0.2 0.1 0.3 0.1 0.1 1.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 120.8 0.1 0.3 0.1 0.0 0.1 0.1 0.3 0.8 0.0 0.1 0.0 0.2 0.0 0.3 1.0 0.0 0.0 2.7 0.0 262.7 0.5 0.0 0.0 0.2 0.0 1.5 10.2 2.3 1.9 0.1 55.6 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 5.3 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.0 4.0 0.0 0.4 1.6 0.0 0.0 0.0 15.0 30.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 13.2 0.0 0.0 9.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.1 0.3 0.3 0.8 0.3 0.2 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.4 0.0 0.2 1.2 0.0 0.0 1.8 0.0 0.0 1.7 2.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 37.3 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 14.1;kidney: 5.3;parathyroid gland: 8.8;retina: 5.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 85.5;Early spermatids: 34.2;Inhibitory neurons: 18.3;Late spermatids: 29.6;Rod photoreceptor cells: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HDLM-2: 11.2;HEL: 8.8;RT4: 11.7" "Region enriched" "Detected in some" 5 "basal ganglia: 5.2" "Not detected" "Not detected" HPA045483 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA045483: AB_2679344" "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (7.15e-3)" "unprognostic (5.07e-2)" "unprognostic (2.61e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-1)" "unprognostic (7.99e-3)" "unprognostic (2.59e-1)" "unprognostic (4.25e-5)" "unprognostic (2.34e-1)" "unprognostic (8.12e-3)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 14.1 0.4 0.6 0.1 0.0 0.0 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 8.8 0.3 0.0 0.0 0.0 0.0 5.8 0.1 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.4 1.3 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 11.2 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 1.1 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.3 0.6 0.5 0.3 0.0 3.1 0.2 0.3 0.7 0.0 0.5 3.7 85.5 0.0 0.6 0.1 13.7 0.3 34.2 5.3 0.4 0.3 1.8 0.0 1.8 0.0 0.0 0.8 0.0 1.7 0.0 0.1 0.0 0.2 0.0 0.0 18.3 0.6 0.0 0.3 1.1 29.6 0.3 0.2 0.0 1.9 0.0 3.0 0.0 5.5 2.9 0.1 0.0 0.4 0.0 0.2 0.0 0.2 0.2 51.0 0.0 1.7 0.5 1.5 0.8 0.3 0.4 0.1 0.3 0.3 0.0 0.1 NAB1 ENSG00000138386 "NGFI-A binding protein 1" Q13506 2 190646746-190692766 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 102.0;Suprabasal keratinocytes: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002738 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "HPA002738: AB_1079447" "unprognostic (1.44e-1)" "unprognostic (2.65e-2)" "unprognostic (6.02e-3)" "unprognostic (4.04e-3)" "unprognostic (9.05e-2)" "unprognostic (9.45e-2)" "unprognostic (7.12e-3)" "unprognostic (6.41e-2)" "unprognostic (2.13e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.52e-1)" "unprognostic (7.23e-3)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (3.85e-2)" 29.3 20.3 19.4 23.5 16.7 18.6 34.8 50.4 23.5 28.1 7.4 22.8 15.8 32.3 50.1 36.3 27.5 28.0 28.5 18.7 9.7 19.9 37.8 22.8 26.8 13.4 13.2 26.0 17.9 23.5 21.1 26.4 14.9 18.5 25.6 41.4 20.7 20.9 8.0 66.7 17.1 25.2 14.9 19.8 37.9 26.0 13.8 21.2 37.9 17.2 26.3 31.2 24.2 25.9 35.5 25.8 65.0 22.6 24.5 42.7 111.0 35.5 55.7 26.4 29.8 62.8 38.4 39.6 40.6 28.3 48.9 88.4 37.4 45.9 51.8 126.1 31.0 46.7 96.3 30.2 15.8 19.8 22.4 24.6 70.4 55.9 17.1 37.4 41.5 23.9 46.3 33.2 40.6 17.4 28.7 20.0 22.8 38.4 35.2 35.0 46.7 15.9 19.3 34.5 57.9 46.9 41.8 13.9 37.3 82.8 11.4 30.6 29.0 54.5 43.0 31.0 21.6 25.7 30.3 29.5 57.3 17.6 43.7 0.0 1.3 0.6 1.3 1.1 1.9 0.7 1.3 1.7 0.9 0.4 1.4 1.5 2.9 2.6 3.7 0.8 3.3 0.8 19.4 16.7 50.4 23.5 18.7 9.7 13.4 13.2 14.9 14.9 13.8 25.9 24.1 6.4 21.2 14.0 5.9 102.0 23.1 24.6 31.3 26.1 19.7 19.7 18.2 11.5 29.8 12.9 12.5 4.3 9.2 11.4 3.9 10.3 1.4 17.5 10.8 30.1 14.4 12.0 37.2 8.0 11.1 25.2 21.4 23.4 20.3 14.2 44.6 25.7 6.7 6.7 21.2 17.5 14.2 17.3 77.4 3.2 13.4 20.7 39.2 24.4 10.6 12.4 11.3 29.1 28.3 10.2 26.3 14.7 14.9 30.5 4.8 5.1 22.3 15.5 46.0 24.6 39.2 1.7 27.3 55.7 138.9 1.2 16.7 7.3 16.0 29.9 NALCN "bA430M15.1, CanIon, VGCNL1" ENSG00000102452 "Sodium leak channel, non-selective" Q8IZF0 13 101053776-101416508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.1" "Group enriched" "Detected in some" 10 "Astrocytes: 125.4;Excitatory neurons: 265.8;Inhibitory neurons: 277.4;Oligodendrocyte precursor cells: 324.7;Oligodendrocytes: 477.4" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.6" "Cell line enhanced" "Detected in many" "HaCaT: 14.2;HHSteC: 14.4;hTERT-RPE1: 11.0;TIME: 19.8;U-87 MG: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031889, HPA031890, HPA031958" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031889: AB_10669638, HPA031890: AB_10696056, HPA031958: AB_10601039" "unprognostic (4.66e-1)" "unprognostic (6.55e-3)" "unprognostic (1.86e-3)" "unprognostic (6.78e-3)" "unprognostic (1.16e-1)" "unprognostic (1.37e-3)" "unprognostic (8.11e-2)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (5.92e-2)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (1.58e-5)" "unprognostic (1.77e-3)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" 0.5 4.3 7.5 0.4 9.8 0.6 2.7 6.4 10.3 1.5 0.0 0.4 0.6 0.5 1.5 0.2 1.0 2.3 3.3 8.6 10.2 0.3 1.2 1.1 0.3 8.2 5.8 2.8 1.3 2.9 6.8 3.0 7.0 0.3 0.6 6.1 0.8 1.0 0.3 0.5 0.5 0.5 6.8 0.4 0.7 0.6 8.3 0.0 2.4 0.2 0.1 0.5 0.2 13.1 0.1 7.8 1.4 0.2 0.7 0.3 0.1 0.8 0.8 1.8 0.4 0.2 8.9 0.0 0.3 3.6 0.8 14.2 0.0 2.2 5.5 0.0 1.2 0.4 3.8 0.1 14.4 0.2 0.3 0.4 0.5 1.7 4.6 11.0 8.2 0.1 0.1 0.4 5.9 0.0 0.1 0.0 0.4 1.3 1.8 0.0 0.0 0.0 4.6 1.9 1.2 0.6 0.1 0.0 0.8 0.9 0.2 0.1 19.8 0.4 0.1 0.3 1.8 0.1 0.1 0.1 11.4 0.1 0.3 2.6 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 7.5 9.8 6.4 10.3 8.6 10.2 8.2 5.8 7.0 6.8 8.3 13.1 0.1 0.0 0.0 125.4 0.0 0.3 0.0 0.3 0.6 15.4 3.5 4.6 6.2 0.0 0.1 0.0 6.2 1.0 0.0 0.0 0.0 0.8 4.5 0.1 0.2 0.6 0.0 0.0 265.8 0.2 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 26.9 277.4 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 23.4 0.0 2.0 0.0 324.7 477.4 0.3 0.0 1.9 0.0 0.0 0.0 0.1 0.0 2.6 0.0 3.6 0.5 0.2 0.8 0.0 0.1 0.5 0.0 0.1 0.0 0.0 NAT8L "FLJ37478, Hcml3, Shati" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059327-2069089 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adipose tissue: 43.5;brain: 99.0" "Cell type enhanced" "Detected in some" "Astrocytes: 126.7;Excitatory neurons: 46.0;Horizontal cells: 80.8;Inhibitory neurons: 37.6;Muller glia cells: 25.0" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 20.8;SCLC-21H: 25.8;SK-MEL-30: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA040677: AB_2732486" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" 43.5 0.7 56.1 0.1 46.4 0.0 1.6 42.9 99.0 0.0 0.6 0.2 0.1 0.3 1.3 0.1 0.9 0.1 0.8 45.8 29.0 5.3 0.0 0.0 0.2 52.3 46.4 0.2 2.3 0.9 1.8 0.1 57.5 1.0 0.1 3.7 2.3 1.6 5.7 1.0 0.2 0.2 33.0 0.3 0.4 9.0 88.8 0.2 0.3 2.5 0.0 0.0 0.0 38.9 0.1 9.2 4.9 10.0 0.9 0.0 5.7 0.2 0.0 0.2 0.0 4.1 0.3 0.0 1.9 0.0 1.5 0.1 11.1 0.0 0.1 0.0 13.2 0.1 2.1 6.6 1.5 14.5 6.9 0.0 0.2 0.0 0.0 1.8 0.0 3.4 11.5 0.0 0.4 6.2 0.2 20.8 14.1 0.0 4.1 0.7 2.3 0.4 0.2 0.5 25.8 8.6 6.6 0.0 21.4 0.8 0.7 8.3 0.0 0.0 3.3 0.1 5.6 0.0 0.0 0.2 0.0 6.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 56.1 46.4 42.9 99.0 45.8 29.0 52.3 46.4 57.5 33.0 88.8 38.9 0.5 0.0 0.0 126.7 0.0 0.3 0.0 0.0 0.0 14.5 1.4 2.2 2.6 0.0 0.0 1.8 6.2 0.0 5.4 0.0 0.0 4.6 1.1 1.7 0.1 0.4 1.8 0.0 46.0 0.6 0.1 0.2 0.0 1.0 0.0 21.9 0.0 0.0 0.8 80.8 37.6 0.0 0.0 0.0 0.3 3.8 0.0 0.7 10.6 17.8 0.0 25.0 0.0 23.1 15.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.8 0.5 1.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 NCAPG2 "CAP-G2, FLJ20311, hCAP-G2, LUZP5, MTB" ENSG00000146918 "Non-SMC condensin II complex subunit G2" Q86XI2 7 158631169-158704804 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 24.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026631, HPA049637" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear speckles" "HPA026631: AB_1845983, HPA049637: " "unprognostic (2.73e-2)" "unprognostic (1.77e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (7.94e-4)" "unprognostic (1.66e-1)" "prognostic favorable (1.91e-4)" "prognostic unfavorable (3.00e-5)" "unprognostic (5.33e-3)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.79e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.19e-2)" "prognostic unfavorable (4.06e-5)" "unprognostic (2.58e-3)" "unprognostic (1.28e-1)" "unprognostic (8.21e-2)" "unprognostic (7.37e-2)" 3.7 2.5 2.0 8.8 2.2 24.4 5.4 2.5 2.1 4.0 1.3 6.9 4.4 4.3 2.1 6.9 3.0 2.9 2.9 2.2 2.1 2.6 4.1 3.1 12.4 2.0 1.7 3.1 2.2 4.6 3.5 5.9 2.1 2.8 7.6 2.8 3.5 2.8 3.4 6.8 5.8 4.8 1.6 4.6 5.6 14.8 1.8 27.9 3.2 4.1 13.8 4.0 3.9 2.4 103.9 53.7 64.1 41.8 9.5 15.4 25.3 74.3 47.4 89.0 99.0 48.5 52.0 64.0 45.0 30.3 95.1 51.7 53.7 33.8 117.2 68.4 40.4 57.2 64.8 38.8 4.2 72.2 62.3 6.8 3.7 73.1 21.0 16.2 50.4 72.9 71.9 91.6 82.8 111.4 119.2 48.8 63.7 58.8 43.3 69.7 67.8 60.6 22.6 45.9 69.6 54.5 91.6 35.0 20.2 40.4 31.4 46.5 25.9 60.6 45.9 166.2 120.6 61.3 48.2 77.2 64.6 89.6 118.5 5.9 0.9 1.1 5.2 1.2 7.5 1.6 5.2 3.6 2.3 1.0 1.6 1.8 0.7 5.2 5.1 1.1 7.2 2.2 2.0 2.2 2.5 2.1 2.2 2.1 2.0 1.7 2.1 1.6 1.8 2.4 3.6 6.4 1.5 3.9 4.1 4.0 2.1 2.8 1.8 3.9 3.7 3.3 4.8 2.8 4.6 1.8 0.0 6.7 5.1 3.4 0.0 2.3 15.1 4.0 4.6 4.3 0.0 19.6 10.7 3.3 10.4 4.5 4.1 5.9 1.3 12.6 2.9 2.6 7.3 8.4 7.2 2.9 2.0 3.8 5.2 7.2 2.8 4.4 1.8 3.7 2.7 2.1 2.1 10.1 10.7 2.3 0.4 4.1 11.0 1.1 0.3 1.3 6.0 2.8 6.6 4.3 5.7 48.2 18.5 6.1 2.0 2.6 4.9 5.0 5.7 3.0 NCOA6 "AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP" ENSG00000198646 "Nuclear receptor coactivator 6" Q14686 20 34689097-34825651 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 130.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004198, HPA050211" Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004198: AB_1078228, HPA050211: AB_2681052" "unprognostic (2.48e-1)" "unprognostic (4.81e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.65e-4)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.87e-2)" "unprognostic (1.51e-1)" "prognostic favorable (8.78e-5)" "unprognostic (9.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.42e-2)" 10.2 9.0 5.2 9.1 6.7 14.0 9.2 12.7 12.4 10.8 4.8 12.9 13.2 10.7 12.2 11.7 11.3 8.8 9.2 6.1 8.2 9.9 8.4 10.4 8.9 6.3 4.6 11.6 12.6 22.0 10.0 13.5 4.6 9.8 14.5 26.7 12.9 11.3 12.7 13.5 12.0 13.2 2.3 9.4 11.4 18.8 7.4 18.1 13.8 13.1 10.3 10.4 10.5 9.6 25.2 14.7 32.6 19.7 17.5 19.4 21.3 12.0 15.3 21.1 16.9 37.9 17.2 17.7 12.9 21.5 25.8 30.0 29.3 20.2 23.9 9.0 13.2 41.6 16.7 22.4 19.3 23.5 29.4 14.8 36.5 19.8 24.5 14.6 20.2 20.1 21.5 23.7 17.7 16.3 37.5 14.8 6.7 21.0 21.1 24.9 39.3 15.9 15.6 16.6 27.2 18.5 22.0 52.5 20.5 15.0 22.2 18.5 20.0 34.1 20.7 25.6 20.2 26.9 24.3 20.0 22.5 13.5 15.5 1.1 0.6 2.5 0.9 0.5 0.8 1.0 0.8 0.8 1.1 0.8 0.7 0.5 1.5 0.7 0.7 1.0 0.5 0.5 5.2 6.7 12.7 12.4 6.1 8.2 6.3 4.6 4.6 2.3 7.4 9.6 17.3 25.6 16.0 54.9 11.0 17.0 9.1 10.6 13.6 28.8 14.3 10.9 20.1 18.6 11.6 16.5 29.2 13.0 12.2 31.9 5.9 12.5 23.5 16.4 21.3 14.0 10.8 13.3 50.9 12.4 12.1 14.5 15.8 23.3 6.3 18.5 13.9 12.1 10.8 33.7 58.8 17.4 20.3 12.2 10.3 17.3 18.0 13.0 10.6 45.9 17.6 11.5 13.4 54.3 130.4 15.4 12.4 13.5 14.2 16.9 20.3 9.3 17.5 29.8 26.3 16.6 16.9 25.6 27.1 19.2 20.9 15.9 13.1 13.6 17.6 14.6 NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 236.4;Peritubular cells: 207.6;Theca cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 55.0;ASC diff: 52.9;HSkMC: 71.3;NTERA-2: 44.0;SuSa: 57.4;U-2 OS: 80.4;U-266/70: 51.7;U-266/84: 51.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA074457: AB_2686691" "unprognostic (3.49e-1)" "unprognostic (1.65e-1)" "unprognostic (4.20e-1)" "unprognostic (2.19e-2)" "unprognostic (2.71e-1)" "unprognostic (9.04e-2)" "unprognostic (6.79e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (1.89e-2)" "unprognostic (8.10e-2)" "unprognostic (1.96e-1)" "unprognostic (6.81e-2)" 46.8 49.4 43.3 11.1 40.5 1.2 35.1 26.0 39.7 70.5 30.4 35.9 11.1 63.7 24.0 16.8 47.2 23.8 34.6 36.7 89.6 13.0 4.5 19.6 10.9 36.0 41.3 69.8 11.8 8.7 56.3 32.6 46.2 27.3 10.7 20.8 12.7 39.3 14.7 11.9 20.8 33.5 36.7 19.1 20.3 18.5 69.6 6.8 17.4 22.4 6.6 31.4 40.4 32.3 0.1 0.0 55.0 0.0 52.9 20.1 0.1 35.4 0.0 0.8 9.6 0.0 0.0 0.0 0.1 10.6 8.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.3 0.0 31.8 71.3 0.0 10.2 0.0 0.0 0.0 21.7 1.2 0.0 18.0 0.0 27.6 0.1 44.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.1 0.4 0.0 0.4 0.0 57.4 9.4 0.0 0.0 2.6 80.4 0.0 0.1 51.7 51.7 0.0 5.5 0.0 0.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 1.5 0.0 0.0 43.3 40.5 26.0 39.7 36.7 89.6 36.0 41.3 46.2 36.7 69.6 32.3 24.1 25.6 11.0 6.8 0.3 13.0 13.8 0.3 27.9 66.0 2.3 19.8 36.8 15.7 1.4 12.9 20.9 1.9 2.9 18.5 23.5 17.9 2.5 1.4 60.8 18.7 6.7 4.2 7.8 10.7 1.4 103.1 4.1 1.1 0.0 83.9 38.9 0.2 7.3 50.5 21.8 4.3 0.0 7.6 13.3 8.6 236.4 2.8 39.2 9.4 0.7 88.7 0.0 9.5 16.4 4.5 2.6 207.6 0.0 6.9 8.1 1.1 4.1 51.0 98.6 91.4 94.0 28.5 21.8 13.4 8.2 2.5 1.4 121.8 7.1 4.1 NDRG2 "KIAA1248, SYLD" ENSG00000165795 "NDRG family member 2" Q9UN36 14 21016763-21070872 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1885.3;salivary gland: 2081.6;skeletal muscle: 1828.7" "Cell type enhanced" "Detected in many" "Astrocytes: 379.0;Distal tubular cells: 485.2;Muller glia cells: 548.0;Sertoli cells: 598.2" "Cancer enhanced" "Detected in all" "glioma: 78.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "myeloid DC: 204.4" "Lineage enriched" "Detected in all" 11 "dendritic cells: 204.4" "Cell line enhanced" "Detected in many" "Hep G2: 57.0;HMC-1: 39.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002896, HPA003590, CAB017491" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 460000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "Centriolar satellite" "Nucleoplasm, Cytosol" "CAB017491: AB_2298331, HPA002896: AB_1079459, HPA003590: AB_1079458" "unprognostic (9.27e-3)" "unprognostic (2.97e-3)" "unprognostic (1.26e-2)" "unprognostic (5.09e-3)" "unprognostic (2.00e-2)" "unprognostic (2.92e-2)" "prognostic favorable (6.71e-4)" "unprognostic (1.85e-3)" "unprognostic (5.57e-2)" "unprognostic (3.46e-2)" "unprognostic (1.69e-1)" "unprognostic (5.10e-2)" "prognostic favorable (1.43e-12)" "unprognostic (1.46e-1)" "unprognostic (5.56e-2)" "unprognostic (6.11e-2)" "unprognostic (4.19e-2)" 192.0 400.6 1613.1 27.4 1885.3 2.8 321.6 1623.2 1666.4 395.4 1189.8 198.3 72.1 229.7 260.3 229.5 305.0 130.7 327.2 1551.7 1590.0 150.1 544.4 115.5 48.6 1690.6 1686.1 476.1 93.7 278.5 88.5 45.3 1581.9 171.3 111.0 134.1 2081.6 208.0 1828.7 220.3 125.4 127.7 1584.5 152.0 130.9 33.3 1752.7 40.1 99.9 1591.4 100.4 158.0 265.8 1597.9 10.9 2.3 6.8 12.6 1.1 0.0 1.0 0.2 4.5 3.9 2.2 15.1 20.0 0.6 4.0 0.3 6.2 17.6 30.3 6.3 5.4 0.1 10.9 14.3 2.2 57.0 1.3 1.3 39.0 11.8 13.1 0.9 1.9 6.3 0.0 12.6 29.0 1.2 0.6 9.4 5.0 4.0 17.9 35.2 0.8 14.6 0.7 3.7 7.6 27.4 0.1 19.4 3.0 3.3 14.4 17.3 26.6 8.2 0.0 1.2 20.8 0.4 0.4 6.1 4.8 0.3 1.8 0.3 4.7 0.0 6.5 0.7 8.3 1.5 11.4 6.4 12.6 11.9 204.4 4.4 18.7 14.0 1.4 3.0 0.1 7.0 9.4 15.3 1613.1 1885.3 1623.2 1666.4 1551.7 1590.0 1690.6 1686.1 1581.9 1584.5 1752.7 1597.9 98.0 0.0 11.9 379.0 6.7 28.7 83.7 86.4 12.0 6.3 240.7 201.2 180.2 151.5 110.9 40.5 10.4 11.5 9.1 81.4 485.2 104.9 6.3 33.3 11.0 53.9 33.5 8.4 1.1 21.7 0.7 62.3 18.8 40.2 48.8 79.0 164.2 214.9 20.7 3.3 3.9 77.4 57.0 30.8 137.6 14.4 348.6 30.4 321.9 47.8 8.7 548.0 1.0 42.7 71.0 16.3 37.9 166.3 1.2 68.5 18.5 41.3 70.8 15.5 598.2 167.7 162.8 1.7 5.5 21.6 30.4 21.6 11.9 66.8 118.9 155.9 NECAP2 FLJ10420 ENSG00000157191 "NECAP endocytosis associated 2" Q9NVZ3 1 16440721-16460078 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 314.8;monocytes: 202.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028077 Approved Approved "Endoplasmic reticulum" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Endoplasmic reticulum" "HPA028077: AB_10601273" "unprognostic (6.92e-2)" "unprognostic (4.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.73e-2)" "unprognostic (1.28e-1)" "unprognostic (4.35e-1)" "prognostic unfavorable (6.13e-4)" "unprognostic (5.48e-2)" "unprognostic (1.57e-1)" "unprognostic (3.38e-1)" "unprognostic (6.72e-2)" "unprognostic (1.70e-1)" "unprognostic (4.36e-2)" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" "unprognostic (5.58e-2)" "unprognostic (2.58e-2)" 38.1 37.9 28.4 51.7 31.0 29.0 34.3 30.7 32.8 31.6 29.5 30.9 23.4 22.8 19.2 43.5 32.8 30.5 22.2 27.0 30.4 33.2 31.7 51.7 77.6 34.6 29.5 36.8 22.1 23.7 19.8 59.9 31.5 25.4 29.5 14.2 26.6 21.0 8.6 45.7 32.0 30.2 32.0 73.3 30.5 33.7 32.5 55.9 25.7 12.8 63.3 44.4 31.1 32.7 54.1 29.2 30.5 36.0 60.6 65.0 17.9 59.6 83.3 76.8 67.9 32.1 87.1 47.8 70.4 111.2 35.4 35.8 43.1 60.3 63.9 100.0 44.3 46.7 33.4 44.6 78.9 59.8 41.7 73.0 61.6 54.7 44.9 66.2 129.1 54.4 67.0 153.7 69.1 35.3 55.8 63.3 26.6 41.1 41.9 61.2 27.0 79.6 76.9 30.5 19.1 48.6 46.4 27.1 61.9 45.1 30.9 66.1 148.0 49.2 26.8 57.4 41.1 72.5 74.5 47.9 41.6 85.7 49.0 90.2 173.1 112.3 96.1 241.2 95.6 108.8 165.8 114.5 120.1 98.8 168.2 106.6 68.2 121.6 274.7 71.0 214.7 269.9 28.4 31.0 30.7 32.8 27.0 30.4 34.6 29.5 31.5 32.0 32.5 32.7 53.6 22.4 25.0 10.1 47.6 52.3 34.1 60.4 27.3 25.7 37.9 35.1 7.0 22.8 32.2 20.2 314.8 49.0 42.5 34.6 23.5 71.3 61.1 27.0 29.5 67.8 18.7 40.8 7.0 54.2 62.0 33.3 23.9 27.6 27.8 33.0 96.4 11.0 125.7 15.2 7.7 31.8 36.7 94.5 81.8 34.3 29.8 60.5 24.9 7.5 202.0 23.8 55.6 11.6 11.4 121.9 45.8 33.8 24.3 46.6 30.8 22.8 37.4 54.3 39.5 14.7 27.2 26.8 27.4 33.3 56.0 49.4 59.4 72.7 24.0 58.8 NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.9;skin 1: 113.6;vagina: 57.3" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 384.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 56.5;HaCaT: 37.0;MCF7: 24.0;OE19: 24.6;SK-BR-3: 47.8;T-47d: 31.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" No No 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" 0.4 0.1 0.1 0.5 0.1 0.7 13.7 0.3 0.2 26.5 0.0 1.5 0.7 1.2 6.9 98.9 2.9 3.8 0.1 0.1 0.0 3.1 0.1 3.5 0.1 0.1 0.1 0.0 4.5 0.4 0.6 12.2 0.1 9.4 1.7 0.1 33.6 4.3 0.6 113.6 0.6 0.1 0.0 0.0 8.8 0.6 0.3 0.8 0.2 0.0 14.5 16.8 57.3 0.4 10.9 0.4 0.0 0.1 0.0 0.1 56.5 0.1 0.1 0.1 0.2 0.0 14.6 0.0 0.2 0.0 0.1 37.0 0.0 1.2 0.2 0.0 0.5 0.0 0.8 11.1 0.0 0.1 0.7 0.0 14.6 3.0 3.6 0.1 0.0 0.0 0.0 0.1 0.1 24.0 0.1 0.1 0.1 24.6 0.0 0.0 0.0 0.1 0.0 17.5 0.0 0.2 0.2 47.8 0.0 6.4 31.1 0.0 0.0 0.1 2.4 0.5 0.2 0.2 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.2 6.4 9.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.6 17.8 0.0 0.0 8.1 16.5 0.0 39.4 0.4 0.0 0.0 41.7 0.0 28.1 2.9 0.6 0.0 0.0 0.0 30.0 67.1 1.2 0.0 43.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 67.1 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 384.2 0.4 0.1 0.0 0.0 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "NEDD4 like E3 ubiquitin protein ligase" Q96PU5 18 58044226-58401540 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.2;Excitatory neurons: 280.9" "Cancer enhanced" "Detected in all" "prostate cancer: 29.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "T-reg: 5.1" "Lineage enriched" "Detected in many" 4 "T-cells: 5.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 146.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 11.2 16.8 20.9 6.7 34.4 27.0 25.8 25.1 31.3 7.6 0.7 38.8 18.7 5.3 10.0 12.0 9.1 9.5 26.9 32.3 16.2 53.4 36.5 47.9 4.1 10.9 18.4 6.4 60.5 13.6 28.4 12.0 10.4 64.2 42.8 20.5 27.5 20.4 34.0 11.2 33.8 6.2 8.6 7.9 51.5 7.8 16.7 4.5 17.4 13.1 7.9 19.4 5.9 16.3 70.7 24.5 14.6 20.9 5.1 2.1 49.8 19.2 88.2 48.6 74.6 28.6 37.1 15.1 57.7 7.4 51.3 50.3 19.5 86.1 100.8 34.9 15.5 10.6 14.3 111.3 2.4 0.5 6.0 13.0 54.6 66.4 78.8 39.1 4.0 13.2 18.7 6.3 20.0 16.2 1.0 1.0 12.2 26.7 33.3 14.3 20.1 17.6 47.0 88.7 17.5 5.0 16.1 5.1 146.1 28.3 29.4 5.6 28.8 131.5 38.5 7.5 83.4 8.3 15.3 9.5 27.6 10.8 10.8 0.7 0.3 1.2 0.2 0.3 0.5 0.8 0.6 0.1 0.1 0.3 0.3 0.2 0.2 0.3 0.1 0.1 5.1 0.3 20.9 34.4 25.1 31.3 32.3 16.2 10.9 18.4 10.4 8.6 16.7 16.3 6.0 253.2 144.8 110.4 5.1 112.8 161.2 34.0 86.6 18.1 99.5 65.9 47.8 64.3 112.8 62.5 173.0 13.0 3.6 144.5 49.0 35.7 22.6 64.0 7.3 14.7 45.2 57.9 280.9 49.2 4.7 9.5 114.7 75.0 3.8 4.7 17.5 41.3 7.3 62.2 173.3 201.5 101.7 8.4 8.2 6.6 3.4 13.3 14.2 88.1 7.3 45.2 2.1 11.1 105.0 49.9 145.3 17.7 12.7 126.9 127.3 91.6 72.7 10.0 0.0 34.3 6.0 1.1 12.5 62.3 53.0 80.0 6.6 8.2 72.9 155.5 NEFM "NEF3, NF-M, NFM" ENSG00000104722 "Neurofilament medium" P07197 8 24913758-24919098 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 689.9" "Cell type enhanced" "Detected in many" "Early spermatids: 92.6;Excitatory neurons: 46.6;Late spermatids: 114.6;Rod photoreceptor cells: 69.1;Spermatocytes: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 25 "HEK 293: 3890.8" "CAB010900, CAB012976, HPA022845, HPA023138" Enhanced Enhanced "Intermediate filaments" Yes NA 220000 "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Intermediate filaments" "CAB010900: AB_477261, CAB012976: AB_2533154, HPA022845: AB_1854399, HPA023138: AB_1854398" "unprognostic (1.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.59e-2)" "unprognostic (9.38e-2)" "unprognostic (5.17e-2)" "unprognostic (6.32e-3)" "unprognostic (6.10e-3)" "unprognostic (2.57e-1)" "unprognostic (8.55e-3)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-2)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (4.76e-2)" "unprognostic (2.61e-2)" 0.3 19.5 61.1 0.9 27.9 0.0 0.1 150.0 689.9 9.6 0.0 2.8 0.1 4.0 0.0 4.0 5.3 0.2 0.2 57.7 54.0 1.9 0.1 0.2 0.1 610.3 89.1 1.7 2.0 0.0 17.9 0.2 487.1 1.5 0.7 90.8 0.3 27.6 1.7 0.6 1.3 2.5 86.8 0.1 0.9 18.9 430.5 1.7 0.1 0.7 0.5 0.4 6.5 203.6 0.0 0.0 154.3 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3890.8 0.0 0.0 0.0 79.4 0.0 0.1 2.4 0.1 0.6 0.0 0.0 0.0 0.7 0.0 0.2 5.9 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 3.7 32.6 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 27.9 150.0 689.9 57.7 54.0 610.3 89.1 487.1 86.8 430.5 203.6 3.1 0.0 0.0 12.4 0.0 1.3 0.2 0.1 9.1 30.9 1.1 21.2 2.4 0.0 0.6 0.0 6.2 0.0 3.2 0.1 0.0 0.1 92.6 0.7 19.5 2.9 3.5 0.0 46.6 0.2 0.0 2.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 20.2 17.5 0.0 0.0 0.0 0.7 114.6 0.9 0.7 1.8 13.1 0.0 22.8 0.0 9.5 13.6 0.0 0.0 4.5 0.4 0.3 0.0 0.4 0.0 69.1 0.0 3.3 5.7 43.8 1.0 14.0 0.3 0.0 4.1 0.0 0.1 0.4 NEIL2 "FLJ31644, MGC2832, MGC4505, NEH2" ENSG00000154328 "Nei like DNA glycosylase 2" Q969S2 8 11769639-11787345 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 68.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA073029, HPA073916" Supported Nucleoplasm,Vesicles NA NA "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA073029: AB_2732216, HPA073916: AB_2732245" "unprognostic (1.52e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (9.88e-2)" "unprognostic (2.18e-2)" "unprognostic (5.72e-2)" "unprognostic (2.70e-1)" "unprognostic (2.88e-2)" "unprognostic (5.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.99e-3)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (5.29e-2)" "unprognostic (1.91e-1)" "unprognostic (2.09e-1)" "unprognostic (4.05e-1)" 9.5 27.8 29.2 5.9 28.8 2.3 9.5 27.7 27.9 13.1 23.8 8.6 2.8 9.5 12.5 6.9 15.0 5.7 14.6 29.6 35.6 12.8 16.3 7.4 7.1 32.0 34.3 11.1 11.2 9.0 17.9 6.4 36.8 11.3 4.8 13.4 10.0 8.1 24.5 15.8 6.8 8.5 31.9 12.4 6.9 26.1 36.1 4.7 11.8 13.7 6.9 9.8 8.8 28.3 8.2 22.9 14.1 27.7 6.6 12.2 6.3 13.0 10.6 12.2 8.4 7.1 8.8 3.2 4.9 15.7 26.3 7.1 13.5 14.1 16.7 9.7 6.7 11.3 5.7 13.9 5.3 5.0 8.2 10.8 20.7 10.7 9.9 11.8 11.6 3.7 16.1 10.8 15.0 8.6 0.9 5.2 12.6 33.9 12.1 14.4 18.1 8.8 14.4 12.3 21.5 17.0 10.2 5.3 19.1 11.2 8.4 0.7 14.3 13.9 19.8 3.8 18.4 10.0 22.3 5.7 36.6 16.7 28.8 0.7 2.2 0.2 12.7 3.9 17.5 21.9 12.9 15.3 4.6 16.9 18.7 16.8 1.3 15.1 2.0 8.3 9.3 7.0 29.2 28.8 27.7 27.9 29.6 35.6 32.0 34.3 36.8 31.9 36.1 28.3 7.2 0.0 5.8 6.2 14.0 8.5 17.1 8.0 13.6 32.3 13.1 7.7 19.6 14.3 7.0 7.3 16.7 18.6 5.6 1.5 33.2 21.1 1.1 6.9 8.4 8.9 10.1 10.3 6.3 23.3 15.8 10.3 3.1 3.8 2.5 14.9 7.9 23.6 15.1 8.4 6.9 6.1 14.2 6.9 6.6 2.1 14.0 6.8 14.2 0.0 6.6 38.9 11.3 6.0 3.7 15.1 1.0 24.5 3.8 15.3 0.8 32.2 6.8 17.1 6.6 11.8 10.2 19.0 68.1 8.3 12.8 5.3 9.7 8.9 6.2 12.0 NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 121.0;Hofbauer cells: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "Centriolar satellite" "CAB045993: AB_2150651, HPA056828: AB_2683250" "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" 18.0 6.1 33.5 32.6 34.3 19.6 14.7 28.1 32.4 26.1 26.5 22.3 17.5 12.2 3.4 8.5 11.2 25.4 7.4 31.8 37.0 17.2 68.2 24.3 27.4 49.8 41.2 9.0 16.7 1.9 6.1 30.2 33.9 19.6 22.5 11.3 20.6 16.7 8.2 5.4 25.8 18.7 34.4 16.6 27.1 7.8 44.2 10.2 7.3 3.1 31.7 24.3 6.4 30.4 31.8 50.0 47.8 18.8 88.3 113.9 59.3 38.8 61.1 58.4 48.4 47.7 57.0 38.2 61.0 74.6 133.2 5.9 24.7 111.7 39.4 43.7 21.8 104.4 42.1 85.4 105.2 19.4 250.0 152.8 17.8 55.4 56.9 152.3 64.3 17.6 19.5 1.7 105.6 32.6 0.9 20.8 12.2 163.7 45.5 40.6 35.6 19.6 62.6 11.4 21.4 7.5 12.6 23.6 54.5 48.3 51.4 76.4 127.5 42.2 42.8 29.5 26.7 8.4 11.4 21.6 53.5 42.3 57.5 28.1 47.6 76.4 9.2 32.1 5.9 52.5 5.5 7.8 29.0 30.2 0.9 3.8 58.8 23.3 41.4 26.9 7.6 21.6 33.5 34.3 28.1 32.4 31.8 37.0 49.8 41.2 33.9 34.4 44.2 30.4 8.4 9.6 4.7 37.9 24.5 2.4 13.8 18.9 4.6 1.0 9.4 6.5 3.3 18.6 8.8 3.7 0.0 47.1 11.3 8.5 1.9 41.3 18.2 9.4 17.7 8.4 6.0 4.0 8.3 23.3 121.0 11.1 19.4 22.2 22.2 1.1 5.0 43.5 112.0 0.0 5.3 18.2 18.3 10.4 22.5 20.0 5.0 31.2 7.2 12.2 57.7 34.6 8.2 15.1 2.4 30.6 11.9 3.8 5.5 17.1 17.2 38.0 3.3 2.1 0.0 4.9 6.4 1.3 17.1 2.4 1.1 36.1 4.5 2.1 18.7 10.2 NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.5;choroid plexus: 59.5;fallopian tube: 60.1;retina: 85.2" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 652.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 33.3" "Group enriched" "Detected in many" 15 "amygdala: 48.9;basal ganglia: 60.0;cerebral cortex: 105.5;hippocampal formation: 89.6;white matter: 42.0" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.4;naive CD8 T-cell: 111.1" "Lineage enriched" "Detected in many" 10 "T-cells: 111.1" "Cell line enhanced" "Detected in some" "AF22: 104.6;HEK 293: 27.5;NTERA-2: 41.2;SCLC-21H: 75.6;U-266/70: 27.5;U-266/84: 29.5;U-698: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" NA NA 6400000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035714: AB_2674746, HPA035715: AB_10669602" "unprognostic (4.25e-3)" "unprognostic (4.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (7.18e-2)" "unprognostic (5.85e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (1.71e-5)" "unprognostic (8.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.75e-2)" 4.6 16.9 48.9 10.9 60.0 7.3 1.9 1.3 105.5 23.1 59.5 2.0 26.3 2.2 0.4 1.2 60.1 1.9 0.4 89.6 4.5 1.2 1.0 5.0 20.7 0.0 0.0 0.8 0.9 0.2 34.6 0.3 0.0 27.2 2.1 85.2 1.4 2.0 0.3 13.4 15.3 2.8 0.0 6.2 2.9 3.0 0.8 8.7 6.5 0.6 15.7 4.1 4.2 42.0 0.3 0.1 104.6 3.5 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 8.3 12.4 0.0 0.0 0.2 25.3 0.2 0.0 0.0 27.5 0.4 8.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.1 1.6 0.2 0.4 0.0 0.4 0.2 0.4 41.2 0.0 14.0 0.2 12.7 0.2 0.0 0.0 75.6 1.8 0.0 0.4 0.0 1.3 0.1 0.7 0.0 0.4 3.8 0.1 2.1 27.5 29.5 40.3 0.2 0.2 0.4 0.2 0.2 0.0 5.0 0.1 24.9 0.2 30.3 52.9 0.1 0.1 70.4 111.1 0.5 11.0 0.1 0.1 0.4 26.7 48.9 60.0 1.3 105.5 89.6 4.5 0.0 0.0 0.0 0.0 0.8 42.0 0.3 0.0 1.3 48.0 1.0 1.1 0.0 0.0 5.7 35.4 0.4 0.6 0.5 2.8 6.2 0.0 33.3 0.1 2.5 5.8 0.0 0.0 0.4 0.7 0.8 0.7 0.0 0.0 652.4 0.2 0.3 3.7 0.0 0.3 0.0 49.4 0.0 0.0 0.1 1.7 108.4 0.9 0.0 0.0 1.5 1.0 0.0 0.4 0.0 18.7 1.3 7.9 1.0 74.4 16.5 0.4 0.4 0.4 0.5 0.3 18.5 0.2 21.9 58.3 0.0 4.1 4.6 1.9 4.2 0.2 1.1 0.1 23.4 0.1 2.9 0.1 NFX1 "MGC20369, NFX2, TEG-42, Tex42" ENSG00000086102 "Nuclear transcription factor, X-box binding 1" Q12986 9 33290512-33371157 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056310, HPA061382, HPA073519" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA056310: AB_2683097, HPA061382: AB_2684496, HPA073519: AB_2686614" "unprognostic (3.90e-2)" "unprognostic (6.01e-2)" "unprognostic (1.19e-2)" "unprognostic (1.40e-1)" "unprognostic (3.07e-2)" "unprognostic (2.02e-2)" "unprognostic (9.11e-2)" "unprognostic (1.81e-2)" "unprognostic (8.71e-2)" "prognostic favorable (3.75e-4)" "unprognostic (3.40e-2)" "unprognostic (1.27e-1)" "unprognostic (1.13e-3)" "unprognostic (3.36e-2)" "unprognostic (1.14e-2)" "unprognostic (9.62e-2)" "unprognostic (3.20e-2)" 16.8 16.8 13.7 15.6 14.5 21.9 20.6 20.4 17.6 15.5 15.9 17.1 16.9 17.4 15.7 18.3 15.4 12.4 23.4 13.8 15.0 14.6 27.7 16.0 22.3 13.7 12.8 21.9 15.8 23.4 13.5 13.5 13.5 16.5 19.1 19.4 17.9 16.0 37.7 25.5 17.5 15.7 10.9 18.2 15.8 12.2 14.0 26.3 22.9 26.5 25.2 16.8 15.7 18.2 29.8 24.0 21.4 20.3 31.3 35.1 21.5 27.6 27.4 30.6 30.5 21.7 11.9 46.0 17.0 32.0 20.5 16.3 38.8 29.8 28.4 33.9 18.9 24.1 58.2 24.5 38.1 43.3 25.6 32.7 48.9 26.1 65.4 27.3 18.9 25.6 37.6 38.3 32.2 20.9 28.3 40.7 34.7 21.9 26.8 30.0 23.3 25.2 20.7 28.1 29.3 20.6 27.5 29.3 15.9 25.1 17.0 42.7 23.8 24.8 20.6 18.1 30.4 20.4 19.9 44.6 27.3 21.5 14.4 35.9 5.5 10.4 9.8 8.9 10.5 13.0 10.7 10.8 9.0 10.3 11.8 11.9 3.5 9.3 7.4 15.4 7.6 6.7 13.7 14.5 20.4 17.6 13.8 15.0 13.7 12.8 13.5 10.9 14.0 18.2 16.0 60.9 42.5 35.3 41.9 8.4 24.6 12.5 21.6 29.3 13.2 13.5 36.9 22.8 35.4 27.6 54.2 12.5 17.2 20.6 7.9 16.1 65.9 16.7 19.0 14.9 9.1 25.2 59.7 13.2 11.8 18.5 26.5 19.8 18.9 15.7 17.5 32.4 15.0 21.9 59.0 23.9 12.2 19.4 10.2 17.0 18.3 19.0 3.6 47.8 16.4 13.7 16.5 37.7 55.0 12.4 21.6 23.0 47.1 25.3 23.3 8.2 43.7 32.2 13.1 27.3 17.5 16.1 14.8 20.9 11.2 18.1 20.9 19.2 16.7 21.0 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122677 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 5.0;Exocrine glandular cells: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 6.8;K-562: 6.1;SCLC-21H: 6.1" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favorable (5.30e-4)" 1.2 1.4 2.0 0.8 2.3 1.1 2.0 1.5 2.6 0.8 0.8 1.5 1.4 0.8 2.6 1.1 1.4 0.6 1.8 2.4 1.9 0.8 4.1 1.2 0.6 2.5 1.8 1.4 1.8 1.2 1.2 0.5 2.7 1.2 1.3 2.0 2.3 1.0 2.6 3.8 1.9 0.8 1.6 1.1 1.3 0.7 2.0 1.0 1.6 1.5 0.8 0.9 0.8 3.6 2.6 1.5 0.6 0.0 1.3 1.2 0.0 2.6 0.8 0.9 0.5 0.1 2.1 0.0 6.8 1.9 0.2 3.0 0.0 1.7 0.7 0.1 0.9 0.4 1.0 0.1 2.0 0.0 1.7 2.1 2.5 1.0 0.9 0.6 2.1 0.0 6.1 0.1 2.1 2.8 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.1 1.4 2.8 6.1 0.1 5.3 4.3 1.6 0.6 3.1 1.7 0.4 0.2 1.3 1.8 0.1 0.1 0.0 0.1 0.1 0.0 2.6 0.5 4.4 0.4 0.6 4.9 0.8 2.3 1.1 0.5 4.7 1.3 1.5 1.0 0.3 1.6 2.3 0.6 1.3 1.8 2.0 2.3 1.5 2.6 2.4 1.9 2.5 1.8 2.7 1.6 2.0 3.6 0.8 0.0 2.2 0.3 0.2 1.9 1.4 1.4 1.8 0.4 1.5 2.0 0.9 1.5 2.3 0.0 0.0 0.4 0.0 0.2 0.0 2.9 0.0 0.6 1.3 0.3 3.5 5.0 1.0 3.7 0.0 0.8 1.5 0.5 1.3 0.8 0.4 1.1 1.2 0.0 0.7 0.3 0.0 0.8 0.6 0.0 0.6 1.5 1.8 1.0 0.5 1.1 0.0 1.5 1.2 2.0 0.3 0.0 0.0 0.2 0.6 1.2 0.8 1.0 0.0 0.3 0.8 0.2 0.2 1.3 1.8 0.4 0.1 1.1 0.5 0.5 NINJ1 NIN1 ENSG00000131669 "Ninjurin 1" Q92982 9 93121496-93134251 "Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 286.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 539.9;Langerhans cells: 741.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1668.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 1668.9" "Cell line enhanced" "Detected in many" "Hep G2: 197.5;MCF7: 191.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045063 Uncertain "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" "HPA045063: AB_10964133" "unprognostic (1.23e-2)" "unprognostic (8.25e-3)" "unprognostic (3.64e-3)" "unprognostic (1.40e-2)" "unprognostic (8.18e-2)" "unprognostic (1.28e-2)" "unprognostic (4.29e-2)" "unprognostic (5.88e-2)" "unprognostic (6.82e-2)" "unprognostic (9.06e-2)" "unprognostic (1.93e-1)" "unprognostic (1.74e-2)" "unprognostic (9.45e-3)" "unprognostic (2.51e-1)" "unprognostic (2.69e-2)" "unprognostic (1.40e-3)" "unprognostic (7.46e-3)" 60.9 129.8 51.0 39.9 48.9 286.9 53.0 47.9 58.7 47.6 50.2 60.1 27.0 36.5 20.2 25.7 47.6 39.2 64.0 44.2 51.9 100.4 118.0 65.0 41.5 54.5 53.2 35.9 35.0 137.7 59.2 66.6 53.3 58.9 16.5 6.1 77.3 56.2 38.0 80.4 37.6 36.0 57.6 89.9 42.5 37.6 57.2 30.5 71.4 30.0 19.6 100.5 37.9 59.2 45.0 68.2 13.2 30.0 47.4 19.1 51.6 30.2 85.9 43.5 26.7 29.5 15.5 0.6 15.0 29.7 47.6 44.8 14.7 84.6 9.4 103.3 28.7 6.8 17.2 197.5 163.7 4.8 13.8 62.5 80.9 41.1 22.5 132.4 41.3 16.3 5.0 49.6 9.9 191.1 13.9 13.8 18.7 51.9 53.0 24.6 10.3 79.0 35.0 18.6 4.3 18.4 67.3 105.4 41.9 22.0 81.9 31.3 31.1 15.8 44.6 33.2 22.9 26.2 11.4 1.0 48.2 14.8 12.1 152.9 313.3 824.9 69.8 315.4 94.5 7.8 65.0 59.3 75.9 2.4 76.5 55.1 1668.9 44.7 355.8 10.7 73.8 219.1 51.0 48.9 47.9 58.7 44.2 51.9 54.5 53.2 53.3 57.6 57.2 59.2 15.7 28.9 41.6 6.5 24.3 114.6 75.8 273.0 130.3 1.8 117.8 96.6 31.6 62.9 80.7 40.5 0.0 128.3 45.8 19.4 129.1 95.2 3.9 22.9 20.9 46.9 18.0 3.0 3.4 101.7 78.3 64.9 20.9 24.5 47.0 13.8 23.6 48.5 539.9 1.7 3.9 21.3 111.9 176.9 741.7 21.1 42.0 278.1 147.7 18.7 214.9 76.1 33.0 3.0 1.7 68.7 23.7 72.6 32.5 60.3 75.5 240.6 18.8 3.8 13.1 45.7 53.3 0.9 11.4 36.3 135.7 73.3 54.7 4.5 19.7 76.9 NIPSNAP1 ENSG00000184117 "Nipsnap homolog 1" Q9BPW8 22 29554808-29581327 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 291.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 116.7;Proximal tubular cells: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059227 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA059227: AB_2683951" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (2.15e-2)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.20e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.78e-1)" "prognostic favorable (8.82e-6)" "unprognostic (2.81e-2)" "unprognostic (8.69e-2)" "unprognostic (9.03e-2)" "unprognostic (1.72e-1)" 10.7 43.9 35.4 17.5 37.8 15.5 31.5 31.8 38.5 21.5 33.4 37.4 67.0 19.4 24.9 25.8 26.8 19.8 21.8 37.6 41.7 117.8 291.8 17.8 23.3 37.1 36.5 32.3 24.4 68.0 36.5 17.3 39.3 23.9 38.5 46.2 26.0 27.2 4.4 20.6 49.2 17.8 30.7 19.1 29.3 11.9 36.7 36.7 32.9 5.4 28.3 20.1 18.3 31.7 69.1 81.1 165.3 206.9 29.2 59.4 30.7 39.5 70.7 53.2 68.7 55.5 90.6 48.8 76.8 56.9 56.0 68.2 87.7 100.7 65.1 98.8 90.5 16.8 37.0 173.5 44.1 36.5 23.0 59.5 50.8 44.1 55.0 129.0 73.4 105.3 31.8 78.9 49.2 156.4 59.3 50.1 140.0 106.2 67.5 115.9 51.7 142.6 128.3 59.1 203.9 179.5 46.1 83.2 92.1 79.5 137.1 57.7 34.7 23.2 79.6 28.6 31.9 106.4 56.5 45.6 62.1 57.3 39.4 10.8 9.4 15.9 34.2 17.4 41.2 29.0 34.4 36.2 21.6 27.3 32.6 39.5 13.8 39.5 10.7 11.0 44.9 22.1 35.4 37.8 31.8 38.5 37.6 41.7 37.1 36.5 39.3 30.7 36.7 31.7 7.4 25.6 15.7 6.8 16.3 4.8 12.6 15.8 18.8 22.6 25.5 18.5 22.9 28.6 18.6 42.3 10.4 44.4 9.2 14.4 68.4 45.8 2.1 6.2 13.7 10.1 41.9 24.6 16.9 18.5 14.6 14.2 25.5 12.0 26.0 33.5 11.7 116.7 14.4 10.1 19.9 31.5 26.4 8.7 4.3 6.1 11.1 8.1 5.4 3.7 21.3 38.7 28.8 6.6 10.3 17.8 20.2 14.3 7.3 6.8 35.2 134.7 9.8 24.4 13.1 7.2 12.3 1.4 8.3 20.5 8.1 14.8 20.5 48.1 47.4 8.8 NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Group enriched" "Detected in many" 4 "dendritic cells: 3163.4;NK-cells: 7721.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 5 "NB-4: 180.8;THP-1: 54.5;U-937: 46.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" 12.5 7.9 3.7 23.2 3.6 602.6 7.7 3.6 6.3 5.9 4.2 9.5 11.0 12.5 6.1 7.2 7.9 21.4 6.7 3.5 3.6 6.5 23.5 49.2 136.4 4.9 3.9 4.2 2.2 2.2 3.2 7.9 4.2 4.9 7.3 0.4 9.6 4.5 6.5 2.7 14.6 7.7 4.1 154.6 10.6 3.3 4.3 9.4 6.6 3.3 21.9 16.7 4.4 4.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.9 7.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.6 0.6 2.0 0.8 0.2 0.0 20.1 3.6 0.0 0.0 0.3 0.0 0.2 0.0 2.5 0.5 0.8 0.0 0.0 2.4 180.8 0.0 0.2 0.3 4.4 9.4 0.4 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.3 0.0 54.5 0.4 0.1 0.2 0.6 0.1 2.6 0.9 0.9 0.1 46.6 0.0 76.9 34.1 15.2 6827.0 131.7 2871.2 37.9 811.1 4295.0 87.1 15.4 261.0 3114.2 111.7 4796.8 104.8 67.1 17.5 4929.2 3.7 3.6 3.6 6.3 3.5 3.6 4.9 3.9 4.2 4.1 4.3 4.2 17.2 3.2 8.0 0.0 24.5 5.0 0.1 0.0 0.0 0.0 5.7 3.7 0.7 28.6 1.3 5.5 0.0 1.0 3163.4 1.9 3.9 1.0 0.2 2.7 3.6 7.1 0.0 186.5 0.0 0.0 0.8 5.2 17.3 4.2 24.1 0.2 55.3 9.9 15.0 0.0 0.0 0.5 0.0 132.9 10.2 0.3 0.0 55.5 17.8 1.0 49.4 0.0 7721.0 0.0 0.2 0.0 1.2 0.0 120.4 0.0 0.6 9.2 0.7 0.0 0.0 6.4 4.7 0.0 0.5 1.1 6.5 1.1 1321.5 0.0 1.1 0.1 NNMT ENSG00000166741 "Nicotinamide N-methyltransferase" P40261 11 114257787-114313536 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 388.9" "Group enriched" "Detected in many" 6 "Hepatocytes: 3913.2;Skeletal myocytes: 1639.1" "Cancer enhanced" "Detected in all" "renal cancer: 204.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 255.3;LHCN-M2: 144.1;RPTEC TERT1: 479.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059180 Approved Approved "Golgi apparatus,Cytosol" NA NA 410000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" Cytosol "HPA059180: AB_2683940" "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" "unprognostic (1.61e-2)" "unprognostic (6.14e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (2.07e-4)" "unprognostic (1.76e-1)" "unprognostic (5.84e-2)" "unprognostic (2.71e-2)" "unprognostic (2.48e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-6)" "prognostic unfavorable (1.75e-4)" "unprognostic (1.11e-1)" "unprognostic (3.37e-3)" "unprognostic (2.77e-2)" 130.9 11.4 1.0 25.2 1.1 0.9 91.9 1.4 1.5 36.0 1.9 37.1 1.5 31.0 2.8 15.4 55.0 43.1 35.5 1.3 1.4 24.1 388.9 64.6 9.6 3.9 1.6 21.3 11.4 1.6 10.6 23.8 2.2 31.9 8.7 0.3 21.1 3.1 73.1 49.3 32.2 30.1 1.7 36.7 30.1 2.2 1.2 2.7 33.0 5.3 8.8 48.6 33.9 3.1 0.2 17.6 0.3 18.6 92.0 118.3 0.1 21.2 58.7 35.2 69.2 0.0 17.5 0.2 58.1 45.1 4.2 0.2 0.0 8.0 34.1 0.2 0.0 0.2 16.7 0.0 123.3 0.2 0.0 255.3 89.4 24.1 37.3 29.8 50.1 0.1 0.3 0.2 144.1 0.1 0.1 0.2 0.1 0.0 0.5 0.2 79.0 0.0 479.6 0.1 0.2 0.2 97.7 0.1 0.3 5.3 0.0 0.2 37.4 18.3 34.3 23.8 3.1 0.3 0.3 0.4 6.4 0.3 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 1.1 1.4 1.5 1.3 1.4 3.9 1.6 2.2 1.7 1.2 3.1 411.8 44.8 411.3 1.0 11.2 103.6 13.2 16.5 2.2 1.9 38.5 73.9 4.7 75.8 13.3 80.9 0.0 1.0 1.6 0.0 9.8 238.3 0.3 19.0 89.9 190.0 5.3 147.2 1.3 157.0 2.5 452.2 5.1 80.5 13.9 0.5 195.2 3913.2 28.4 0.0 1.6 0.0 0.0 126.8 142.1 1.6 74.3 9.2 96.0 1.9 5.7 0.0 0.0 0.0 0.2 323.1 0.0 13.2 1.5 10.8 0.0 99.2 11.9 0.2 0.0 1639.1 154.3 0.3 0.8 1.9 92.1 2.2 20.1 0.0 0.0 3.1 NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.2;breast: 19.8" "Group enriched" "Detected in many" 4 "Adipocytes: 263.8;Endothelial cells: 121.0;Hepatic stellate cells: 188.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 6400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.27e-1)" "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (9.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.88e-2)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.13e-1)" 24.2 4.0 0.0 0.5 0.0 0.0 19.8 0.0 0.0 5.8 0.0 3.6 0.5 7.2 3.2 2.7 5.8 0.0 15.8 0.0 0.0 8.5 2.5 18.5 0.4 0.0 0.1 2.8 2.6 0.0 3.0 1.4 0.0 6.0 0.1 0.0 2.6 0.0 5.6 2.8 3.9 0.0 0.0 2.6 3.9 0.9 0.0 0.0 9.6 0.0 0.1 5.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 263.8 0.0 6.1 0.0 6.0 5.2 32.1 9.9 13.6 2.7 2.6 6.6 8.7 0.0 4.2 5.5 4.2 0.4 11.9 0.6 0.0 2.6 46.0 2.6 3.1 121.0 6.0 12.0 0.2 1.1 0.3 4.7 0.0 1.0 0.0 1.8 188.8 2.3 1.7 6.7 0.2 0.8 4.1 9.3 5.2 35.6 7.2 6.8 3.6 10.3 1.6 21.0 0.0 0.0 0.5 0.4 0.3 5.3 0.7 18.0 1.0 0.9 3.1 3.6 0.0 7.8 9.3 5.5 1.9 1.9 1.6 0.3 3.6 3.7 0.9 5.6 NOX4 "KOX, KOX-1" ENSG00000086991 "NADPH oxidase 4" Q9NPH5 11 89324353-89498187 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 138.0" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 164.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 14.3;HUVEC TERT2: 27.7;TIME: 70.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.91e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-3)" "unprognostic (6.58e-3)" "unprognostic (1.92e-1)" "unprognostic (2.33e-1)" "unprognostic (8.83e-3)" "unprognostic (8.95e-3)" "unprognostic (3.80e-1)" "unprognostic (6.88e-2)" "unprognostic (1.56e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.14e-4)" "unprognostic (1.99e-4)" "unprognostic (9.71e-2)" "unprognostic (5.69e-2)" "unprognostic (3.03e-3)" 7.8 0.7 0.7 0.7 1.2 0.2 3.8 0.7 1.2 1.5 0.0 1.2 0.2 4.9 0.4 0.4 1.3 2.4 7.6 0.4 0.6 138.0 0.3 1.5 0.2 1.0 0.7 0.8 0.3 3.6 0.9 3.1 0.9 1.0 0.3 17.1 3.0 1.3 1.7 1.4 0.6 3.4 0.8 0.4 0.5 0.3 0.7 0.1 2.1 3.5 0.5 1.4 1.1 1.7 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.5 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.1 14.3 27.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 6.1 0.0 0.0 0.3 7.1 0.4 0.0 70.6 0.2 5.0 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 1.2 0.7 1.2 0.4 0.6 1.0 0.7 0.9 0.8 0.7 1.7 4.4 0.0 0.0 2.9 1.0 0.6 0.1 0.4 0.0 7.5 0.2 0.3 1.0 0.0 0.0 11.0 6.2 2.2 0.2 0.1 15.6 0.0 0.8 1.0 1.4 5.9 0.0 0.0 30.0 0.0 0.8 9.2 0.0 3.0 0.0 0.6 2.5 0.1 0.2 0.0 21.1 0.0 0.0 0.0 0.5 0.7 0.3 1.3 0.0 6.5 0.1 4.5 0.0 7.1 28.4 0.1 0.0 1.2 0.3 0.1 0.0 164.0 0.0 27.1 0.0 1.2 1.0 0.6 0.7 0.1 0.3 2.5 1.1 0.1 0.0 0.1 NPAS4 "bHLHe79, Le-PAS, NXF, PASD10" ENSG00000174576 "Neuronal PAS domain protein 4" Q8IUM7 11 66421004-66426707 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 170.4" "Group enriched" "Detected in some" 4 "Bipolar cells: 10.2;Horizontal cells: 11.8;Rod photoreceptor cells: 5.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 13 "cerebellum: 170.4;cerebral cortex: 55.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 4.9;cerebellum: 5.0;cerebral cortex: 7.5;hippocampal formation: 4.6;olfactory bulb: 3.8" HPA039255 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA039255: AB_10674282" "unprognostic (7.81e-2)" "unprognostic (9.93e-2)" "unprognostic (1.55e-2)" "unprognostic (1.24e-1)" "unprognostic (2.51e-1)" "unprognostic (1.78e-3)" "unprognostic (4.97e-1)" "unprognostic (7.84e-2)" "unprognostic (1.85e-2)" "unprognostic (3.29e-2)" "unprognostic (3.96e-2)" "unprognostic (1.12e-3)" "unprognostic (1.58e-1)" "unprognostic (1.37e-1)" "unprognostic (4.24e-1)" "unprognostic (3.21e-2)" 0.2 0.2 0.8 0.4 2.9 0.0 0.1 170.4 55.3 0.8 0.5 2.7 0.1 3.3 0.1 0.3 1.3 0.1 0.2 4.2 8.6 0.1 0.1 0.1 0.0 2.2 1.6 0.3 0.3 0.0 19.3 0.0 3.6 1.2 0.1 0.1 0.1 0.7 0.0 0.1 0.5 1.3 0.1 0.0 1.1 0.1 1.2 0.0 0.1 0.2 0.0 1.1 0.5 4.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.9 170.4 55.3 4.2 8.6 2.2 1.6 3.6 0.1 1.2 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.2 0.1 0.4 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.8 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 NPM2 ENSG00000158806 "Nucleophosmin/nucleoplasmin 2" Q86SE8 8 22024125-22036897 "Predicted intracellular proteins" Fertilization "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.0;parathyroid gland: 39.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.4;Cone photoreceptor cells: 20.9;Excitatory neurons: 21.3;Inhibitory neurons: 21.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 10.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 17.7;HEL: 14.5;Hep G2: 32.4;JURKAT: 9.5;THP-1: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041070 Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nucleoli" "HPA041070: AB_2677285" "unprognostic (1.40e-2)" "unprognostic (3.30e-2)" "unprognostic (3.11e-2)" "unprognostic (2.49e-2)" "unprognostic (1.55e-1)" "unprognostic (2.06e-1)" "unprognostic (1.61e-1)" "unprognostic (3.03e-2)" "unprognostic (5.30e-3)" "unprognostic (1.01e-1)" "prognostic favorable (9.02e-4)" "unprognostic (2.23e-1)" "prognostic favorable (3.18e-6)" "unprognostic (8.05e-3)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" "unprognostic (1.30e-1)" 0.6 18.4 11.0 0.1 16.9 1.2 2.1 7.4 40.0 4.9 2.2 1.1 2.2 5.0 0.9 1.0 3.2 1.9 2.3 12.4 9.2 6.6 1.6 1.8 0.6 7.5 7.6 1.5 11.0 39.2 18.5 0.5 10.0 6.6 1.0 5.7 2.7 1.4 0.3 2.2 1.2 3.6 2.3 12.5 1.9 5.1 7.1 2.9 25.3 0.3 0.4 2.0 2.3 13.5 3.9 0.5 0.2 0.2 0.9 0.0 1.5 0.5 0.5 2.4 4.9 1.6 3.6 0.0 1.1 0.0 0.2 17.7 0.5 0.0 1.4 0.1 0.5 14.5 1.0 32.4 3.1 1.9 1.3 0.5 2.3 0.0 0.3 3.7 0.0 9.5 0.5 0.0 0.1 0.0 0.2 3.9 0.7 6.4 0.4 0.3 1.4 0.8 5.6 0.1 3.8 0.2 0.0 0.1 4.6 0.0 0.7 11.2 0.0 0.0 0.3 0.6 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.7 0.0 0.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 11.0 16.9 7.4 40.0 12.4 9.2 7.5 7.6 10.0 2.3 7.1 13.5 0.1 0.0 1.1 1.0 0.7 0.1 9.7 3.7 0.6 29.4 3.1 5.2 2.1 5.7 8.8 0.0 20.9 0.1 0.5 0.6 3.9 9.4 15.1 1.1 0.3 0.6 11.4 0.4 21.3 8.0 0.2 1.7 1.5 1.1 0.0 1.4 2.5 0.5 4.6 6.7 21.9 2.1 2.0 0.0 0.3 14.4 0.6 0.9 10.6 1.9 1.0 0.9 0.0 2.5 1.6 4.3 0.8 0.4 0.6 3.4 0.5 14.6 7.7 4.2 0.0 0.4 1.6 0.5 0.9 1.1 1.1 0.3 2.7 7.6 1.2 5.8 NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35791591-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Excitatory neurons: 69.1;Inhibitory neurons: 68.9;Microglial cells: 34.7;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 30.9;ASC TERT1: 21.1;BJ hTERT+: 20.2;HHSteC: 20.1;HSkMC: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" 12.4 8.2 9.3 1.7 9.4 0.3 10.3 14.4 9.9 25.7 7.7 15.6 1.8 20.5 8.7 3.2 15.1 3.2 12.8 9.1 11.4 6.7 8.6 9.1 2.3 11.8 9.4 9.4 3.2 1.3 13.8 4.7 11.5 10.9 2.8 4.1 5.3 6.5 10.8 8.3 7.5 9.9 8.2 4.9 7.8 4.8 10.7 2.2 6.0 8.6 1.7 12.1 14.7 7.9 0.0 2.9 2.2 0.0 30.9 21.1 1.9 9.3 20.2 7.0 6.4 4.5 4.3 1.8 3.0 17.9 12.8 1.2 3.6 0.2 6.1 2.2 1.0 1.8 4.3 3.4 20.1 0.4 0.0 23.8 1.8 8.9 0.6 7.6 12.7 2.5 0.7 0.2 13.4 1.0 0.5 0.8 3.5 1.0 3.7 2.4 0.2 0.5 1.8 1.4 1.1 0.7 0.4 0.1 0.6 3.8 0.2 0.0 8.2 8.5 7.8 3.2 1.2 0.5 0.6 4.8 10.4 0.6 5.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 9.3 9.4 14.4 9.9 9.1 11.4 11.8 9.4 11.5 8.2 10.7 7.9 2.7 3.2 3.4 35.6 0.0 1.1 0.6 0.6 1.2 5.1 0.7 1.4 0.7 1.5 0.3 0.0 2.1 0.4 0.5 0.7 0.0 0.6 0.3 1.4 9.2 4.4 0.0 0.0 69.1 0.8 0.2 7.2 0.5 2.0 1.3 9.6 6.1 4.5 0.4 3.3 68.9 0.7 0.0 0.3 2.1 0.3 9.3 0.3 0.0 34.7 0.0 6.8 0.0 51.8 16.3 0.6 3.6 7.9 0.2 2.7 0.2 0.6 1.1 2.2 0.0 5.1 3.4 4.5 3.1 0.1 1.6 0.3 0.7 0.8 1.1 0.4 NPY1R NPYR ENSG00000164128 "Neuropeptide Y receptor Y1" P25929 4 163323962-163344832 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 119.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 32.8;Excitatory neurons: 39.8;Hepatic stellate cells: 160.6;Sertoli cells: 46.0;Smooth muscle cells: 34.1" "Cancer enriched" "Detected in many" 13 "breast cancer: 65.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "HEL: 128.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "prognostic favorable (7.68e-5)" "unprognostic (9.14e-3)" "unprognostic (1.55e-1)" "unprognostic (5.09e-2)" "unprognostic (2.60e-1)" "unprognostic (9.29e-2)" "unprognostic (5.28e-3)" "unprognostic (2.26e-1)" "unprognostic (4.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.89e-2)" "unprognostic (5.92e-2)" "unprognostic (7.39e-2)" "unprognostic (1.92e-3)" "unprognostic (5.48e-2)" "unprognostic (1.74e-1)" "unprognostic (2.21e-1)" 30.5 31.0 10.4 2.9 13.1 0.0 32.4 0.0 13.7 7.8 0.0 5.8 1.0 7.3 10.2 1.8 8.4 4.5 4.8 9.1 19.7 32.3 14.7 2.1 17.3 0.3 0.8 2.8 28.7 3.6 3.0 5.2 0.4 2.5 4.5 4.4 21.4 8.3 2.9 9.8 1.5 5.7 5.7 119.6 1.8 4.1 2.2 1.1 7.9 2.6 0.9 1.8 4.9 9.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.0 0.0 7.0 0.0 0.0 0.0 0.0 128.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 1.2 0.0 4.6 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.1 0.0 0.0 0.4 3.0 0.0 0.0 0.1 1.2 0.0 0.6 0.1 0.0 0.0 1.4 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 10.4 13.1 0.0 13.7 9.1 19.7 0.3 0.8 0.4 5.7 2.2 9.0 2.1 0.0 0.5 1.3 0.7 2.8 0.7 0.0 3.4 11.6 19.2 3.3 0.9 1.5 0.0 0.0 2.1 0.0 0.0 3.4 13.7 12.5 5.0 0.0 0.4 10.8 32.8 0.0 39.8 0.0 0.0 5.1 0.0 0.1 0.0 3.7 160.6 0.9 0.1 0.0 18.8 1.6 0.0 7.2 0.9 2.4 11.5 0.1 5.4 4.7 0.0 1.1 0.0 2.0 1.4 0.1 15.9 0.4 0.0 0.5 0.1 0.1 0.0 2.1 46.0 1.1 34.1 0.5 0.6 0.1 1.7 0.0 0.6 0.5 2.1 0.3 NPY5R NPYR5 ENSG00000164129 "Neuropeptide Y receptor Y5" Q15761 4 163343892-163351934 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 7.2;lymphoid tissue: 8.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.6;Granulosa cells: 1.4;Inhibitory neurons: 3.5;Smooth muscle cells: 3.1;Spermatocytes: 3.0" "Cancer enhanced" "Detected in single" "breast cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.63e-6)" "unprognostic (3.00e-1)" "unprognostic (2.79e-1)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "unprognostic (3.74e-2)" "unprognostic (3.94e-2)" "unprognostic (5.40e-2)" "unprognostic (4.30e-2)" "unprognostic (3.99e-2)" "unprognostic (1.76e-1)" "unprognostic (3.94e-1)" 7.2 3.3 0.9 0.3 2.2 0.0 1.7 0.0 1.5 0.7 0.0 0.3 0.0 0.7 1.0 0.2 0.8 0.5 0.7 1.1 2.8 4.6 1.0 0.3 2.4 0.2 0.4 0.2 1.0 0.7 0.3 2.9 0.2 0.2 0.3 0.2 3.7 0.9 0.1 0.8 0.1 0.7 1.1 8.8 0.2 5.1 0.8 0.1 0.7 0.4 0.1 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.2 0.0 1.5 1.1 2.8 0.2 0.4 0.2 1.1 0.8 0.6 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.5 0.0 0.0 4.6 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.1 3.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 NR2F2 "ARP1, COUP-TFII, COUPTF2, COUPTFB, NF-E3, SVP40, TFCOUP2" ENSG00000185551 "Nuclear receptor subfamily 2 group F member 2" P24468 15 96325938-96340263 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 292.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 542.2;Hepatic stellate cells: 395.5;Leydig cells: 510.4;Peritubular cells: 610.5;Sertoli cells: 486.4;Smooth muscle cells: 385.7;Theca cells: 572.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058974 Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA058974: AB_2732629" "unprognostic (9.28e-2)" "unprognostic (2.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.42e-2)" "unprognostic (8.96e-2)" "unprognostic (5.44e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (2.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.89e-1)" "unprognostic (9.19e-2)" "unprognostic (5.14e-2)" "unprognostic (5.96e-2)" "unprognostic (1.72e-2)" "unprognostic (7.47e-2)" "unprognostic (1.28e-2)" 95.5 43.1 32.7 18.8 19.2 0.1 59.7 15.0 19.6 128.6 23.5 52.6 21.5 120.9 61.8 22.1 101.5 65.7 44.4 20.0 24.8 79.8 32.1 56.8 42.4 16.2 21.9 292.4 20.0 30.7 20.3 74.7 18.2 60.6 26.7 2.5 22.9 126.4 33.1 24.1 32.1 81.8 12.5 106.2 82.3 26.7 49.3 7.8 46.2 31.5 15.1 46.3 74.5 10.7 154.7 39.1 125.6 78.5 249.1 85.5 41.9 109.1 83.2 111.1 94.3 134.8 153.4 0.1 86.8 55.2 44.1 90.4 22.3 78.3 138.8 0.5 86.5 49.9 48.7 24.6 69.5 38.7 18.0 61.3 26.5 92.5 19.8 130.5 207.3 0.1 135.3 0.4 71.2 105.5 0.1 27.6 1.2 59.6 52.7 0.1 30.9 0.2 244.7 165.7 15.8 0.2 12.3 3.7 17.5 55.0 61.1 2.8 215.3 119.9 39.7 28.3 38.8 0.1 0.4 0.4 67.0 18.9 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 19.2 15.0 19.6 20.0 24.8 16.2 21.9 18.2 12.5 49.3 10.7 133.4 28.9 18.1 0.7 1.1 14.4 24.9 71.7 39.3 7.5 51.9 50.8 46.4 203.0 34.6 62.5 25.0 126.2 2.0 35.7 46.9 22.0 3.2 70.9 542.2 166.1 26.4 5.3 0.1 10.9 50.3 125.8 80.0 68.9 0.0 41.5 395.5 51.6 10.3 3.3 24.8 35.5 32.6 12.2 20.1 22.9 510.4 5.0 26.6 36.5 0.6 30.2 0.0 0.0 0.5 15.6 23.9 610.5 2.8 22.3 14.3 65.5 37.3 13.8 486.4 27.8 385.7 6.4 7.9 20.5 10.4 35.3 5.8 572.5 27.1 21.3 NREP "C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17" ENSG00000134986 "Neuronal regeneration related protein" Q16612 5 111662621-111997464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 118.3;Excitatory neurons: 116.1;Theca cells: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "myeloid DC: 24.6;NK-cell: 6.9;plasmacytoid DC: 25.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 425.3;SH-SY5Y: 461.8" "Region enriched" "Detected in all" 5 "cerebellum: 1766.0" "Region enhanced" "Detected in all" "cerebellum: 219.5" HPA000545 Approved Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA000545: AB_1845721" "unprognostic (2.85e-2)" "unprognostic (1.00e-2)" "unprognostic (2.30e-1)" "unprognostic (1.48e-3)" "unprognostic (4.37e-1)" "unprognostic (2.26e-1)" "unprognostic (8.16e-3)" "unprognostic (1.58e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (3.76e-2)" "unprognostic (2.02e-1)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (5.76e-3)" 18.9 56.5 50.1 19.4 52.6 36.7 29.3 141.8 71.6 32.3 56.9 28.6 16.9 84.8 17.9 23.0 18.2 65.4 70.9 52.5 44.0 49.5 50.7 27.7 17.3 47.8 52.1 41.8 9.8 8.4 13.3 119.8 50.8 52.7 25.2 107.4 36.1 72.2 179.9 22.1 16.7 54.6 44.6 36.9 25.7 12.7 46.4 168.1 18.6 118.2 18.4 27.5 16.8 54.7 0.6 7.1 425.3 91.5 20.2 46.6 20.3 140.9 83.9 135.7 221.0 0.8 2.8 73.1 44.6 71.3 18.9 0.3 91.0 5.2 69.4 29.5 13.0 57.5 35.2 77.6 28.1 77.0 0.8 45.6 22.5 129.5 44.5 318.6 154.2 81.4 0.6 7.4 143.4 1.6 308.3 53.7 244.1 0.2 33.3 326.3 173.4 19.9 52.2 1.6 96.9 461.8 31.6 2.2 2.9 224.2 17.7 210.6 31.1 163.7 54.1 80.8 15.8 34.6 29.3 92.3 35.6 159.8 32.8 0.0 4.0 0.0 0.0 2.2 0.0 1.6 0.1 0.2 24.6 1.1 1.2 1.6 0.1 6.9 1.0 25.1 0.0 2.2 50.1 52.6 141.8 71.6 52.5 44.0 47.8 52.1 50.8 44.6 46.4 54.7 20.8 6.4 30.8 43.1 3.6 18.1 1.6 4.5 14.2 66.9 12.4 22.6 33.4 8.6 5.7 12.9 87.6 118.3 12.9 2.5 33.2 14.4 2.5 5.4 69.1 38.9 21.6 52.2 116.1 5.5 18.6 31.7 31.1 7.4 5.1 69.9 27.5 10.1 35.5 20.2 51.4 9.3 42.7 10.0 19.0 1.0 8.4 14.9 14.2 17.8 11.5 14.9 5.2 37.2 4.6 8.2 2.0 23.3 0.9 0.7 1.2 61.0 0.5 29.0 13.1 25.4 51.8 0.8 12.6 11.9 12.6 31.5 3.2 150.8 11.3 0.2 NSUN7 FLJ14001 ENSG00000179299 "NOP2/Sun RNA methyltransferase family member 7" Q8NE18 4 40749925-40811184 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.5" "Cell type enhanced" "Detected in many" "Early spermatids: 47.5;Late spermatids: 75.6;Respiratory ciliated cells: 36.4;Spermatocytes: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Cell line enhanced" "Detected in some" "A-431: 2.6;CAPAN-2: 5.5;Karpas-707: 4.0;MCF7: 2.6;SuSa: 3.0;T-47d: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA020653 Uncertain Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA020653: AB_1848710" "unprognostic (2.32e-1)" "unprognostic (4.22e-1)" "unprognostic (4.77e-2)" "unprognostic (1.50e-1)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.63e-1)" "unprognostic (4.01e-3)" "unprognostic (4.37e-2)" "unprognostic (3.06e-1)" "unprognostic (2.24e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.76e-8)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-2)" 0.6 0.9 0.6 1.0 0.6 0.6 3.8 0.4 0.4 2.5 7.2 2.8 1.7 2.2 2.7 1.8 6.8 1.2 2.1 0.5 1.5 4.7 0.4 3.3 0.3 1.8 2.4 2.3 7.2 3.3 3.6 1.3 1.5 4.5 2.4 0.7 4.8 1.5 0.0 1.5 2.1 1.2 1.2 2.7 3.2 16.5 2.0 0.3 4.7 0.2 0.3 1.3 1.2 0.8 2.6 0.1 1.2 0.0 0.0 0.0 1.7 0.0 0.2 0.1 0.1 1.0 5.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 2.6 0.1 0.0 1.4 0.0 0.3 0.1 0.0 0.0 2.4 0.7 0.6 1.5 0.3 1.7 0.0 3.0 3.9 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.4 0.4 0.5 1.5 1.8 2.4 1.5 1.2 2.0 0.8 0.1 9.6 7.8 3.6 4.3 1.1 3.1 1.5 2.2 0.1 8.6 7.1 3.5 0.0 10.5 9.2 0.0 9.2 0.1 2.7 9.8 5.8 47.5 20.7 0.9 0.6 8.3 0.4 0.7 5.4 3.6 1.2 4.6 5.4 0.0 8.5 0.7 0.2 3.8 0.0 0.9 7.1 4.1 0.8 0.4 75.6 1.5 2.2 0.0 8.4 1.0 2.1 0.0 18.1 1.3 4.7 2.7 0.0 0.3 4.5 2.2 5.5 36.4 0.1 0.0 0.4 0.8 38.9 11.4 8.2 1.0 4.5 0.7 3.4 7.7 5.7 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 NTNG2 "KIAA1857, Lmnt2, NTNG1" ENSG00000196358 "Netrin G2" Q96CW9 9 132161676-132244526 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Autism spectrum disorder, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 40.4;brain: 74.6;retina: 26.7" "Cell type enhanced" "Detected in many" "Astrocytes: 34.9;Bipolar cells: 69.6;Cone photoreceptor cells: 171.0;Rod photoreceptor cells: 108.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "basal ganglia: 74.6" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "HL-60: 6.8;HMC-1: 16.2;NB-4: 39.0;U-937: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071290 Approved "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA071290: AB_2686381" "unprognostic (5.01e-2)" "unprognostic (2.95e-2)" "unprognostic (4.12e-2)" "unprognostic (1.01e-1)" "unprognostic (3.59e-1)" "unprognostic (7.67e-2)" "unprognostic (2.73e-2)" "unprognostic (2.87e-1)" "unprognostic (4.86e-2)" "unprognostic (1.47e-1)" "unprognostic (2.62e-2)" "prognostic favorable (6.06e-4)" "unprognostic (9.30e-12)" "unprognostic (1.66e-1)" "unprognostic (3.23e-1)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" 0.6 1.9 18.6 1.1 74.6 40.4 0.2 13.3 25.6 0.8 0.0 0.5 1.2 0.5 0.3 0.3 0.5 0.8 5.5 17.6 6.5 0.7 0.3 2.9 1.4 11.5 5.4 0.2 1.0 4.4 1.7 0.5 14.7 6.2 0.2 26.7 0.8 1.1 0.4 0.4 0.8 0.3 5.0 3.9 0.6 2.1 11.4 0.5 0.4 1.4 0.4 0.8 0.6 11.5 0.0 0.5 0.2 0.6 0.6 0.1 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.2 0.0 0.0 1.1 0.2 0.1 0.1 0.0 0.9 6.8 16.2 0.1 0.0 0.2 0.1 1.4 0.0 1.3 0.0 0.0 0.5 0.2 0.3 39.0 1.4 0.0 0.2 0.4 0.4 0.2 0.0 0.0 4.6 4.2 0.2 0.0 0.1 0.0 0.0 0.6 0.1 0.9 2.8 3.6 0.1 0.1 0.0 0.0 1.3 10.0 1.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 18.6 74.6 13.3 25.6 17.6 6.5 11.5 5.4 14.7 5.0 11.4 11.5 0.8 0.0 0.6 34.9 0.5 0.3 0.6 0.0 0.6 69.6 0.1 1.0 3.0 0.0 0.6 0.0 171.0 0.1 5.0 0.0 0.0 0.3 1.4 0.6 2.4 1.3 0.0 0.4 8.1 0.0 0.0 1.9 0.0 1.1 1.3 0.9 0.7 0.1 0.7 1.7 3.6 0.2 0.0 0.3 0.3 1.3 0.6 1.2 1.8 8.4 0.9 20.3 3.1 11.1 21.5 0.1 0.0 1.2 2.0 2.3 0.0 0.1 0.0 108.3 6.6 2.4 1.8 0.5 0.2 0.2 0.3 0.1 1.2 4.3 0.1 0.3 NVL NVL2 ENSG00000143748 "Nuclear VCP like" O15381 1 224227334-224330189 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028207, HPA028219, HPA028224, HPA028654" Supported Enhanced Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA028207: AB_10601382, HPA028219: AB_2672526, HPA028224: AB_2672529, HPA028654: AB_2672714" "unprognostic (1.50e-1)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (5.77e-5)" "prognostic favorable (2.95e-4)" "unprognostic (4.43e-2)" "unprognostic (7.14e-2)" "unprognostic (3.15e-1)" "unprognostic (2.42e-1)" "prognostic unfavorable (4.10e-11)" "unprognostic (1.67e-1)" "unprognostic (2.01e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" 7.0 7.7 5.5 8.7 5.7 9.8 10.7 7.8 7.5 9.5 6.5 9.1 6.3 9.0 7.7 7.2 8.8 5.6 5.9 5.3 6.4 8.7 6.1 8.0 12.5 5.4 5.3 10.6 8.8 9.5 10.3 13.0 5.6 9.0 10.6 12.8 7.4 7.9 6.5 15.7 8.2 8.1 4.7 10.4 7.2 6.6 5.6 13.0 10.2 5.2 12.1 8.8 8.9 7.5 28.8 15.8 31.2 25.2 11.5 16.6 31.6 22.0 16.5 30.6 27.0 23.4 23.4 39.6 22.5 14.7 11.7 26.1 37.3 22.2 31.5 30.5 47.0 16.4 25.5 11.3 20.3 39.1 28.8 13.5 16.9 26.8 28.5 14.3 19.2 23.0 48.9 23.8 19.1 21.3 30.6 18.3 47.5 20.0 26.1 34.2 37.3 24.8 17.8 19.2 27.5 22.9 34.2 53.1 31.9 25.6 24.3 32.1 19.8 23.2 14.9 27.1 42.9 15.6 33.3 39.3 15.1 30.2 24.8 13.9 7.8 8.4 11.5 11.8 11.7 13.5 11.8 9.1 8.7 9.0 9.9 10.0 0.8 11.9 16.4 9.0 9.3 7.8 5.5 5.7 7.8 7.5 5.3 6.4 5.4 5.3 5.6 4.7 5.6 7.5 10.2 22.4 23.1 21.2 14.3 5.2 4.6 7.8 4.0 14.5 7.9 8.3 10.5 7.2 12.2 1.8 10.4 21.5 12.6 26.9 13.7 9.5 10.1 10.0 11.6 9.3 4.2 7.2 32.1 8.4 14.0 9.3 5.6 7.3 16.4 13.4 4.6 4.5 10.7 10.1 31.0 12.6 10.2 6.5 5.7 3.1 9.6 8.1 5.4 26.2 8.7 9.7 15.5 24.6 43.0 7.0 23.4 10.9 12.3 3.7 7.0 8.1 16.7 20.4 0.0 8.5 10.1 17.5 11.3 7.3 4.5 18.3 12.9 11.4 14.7 3.7 NXN "FLJ12614, NRX" ENSG00000167693 Nucleoredoxin Q6DKJ4 17 799310-979776 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Oxidoreductase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 99.2" "Cell type enhanced" "Detected in many" "Late spermatids: 91.5;Microglial cells: 87.1;Urothelial cells: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 100.7;HHSteC: 106.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023566 Approved Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA023566: AB_1854737" "unprognostic (1.68e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-2)" "unprognostic (3.48e-2)" "unprognostic (7.29e-2)" "unprognostic (1.00e-1)" "unprognostic (1.75e-2)" "unprognostic (6.98e-2)" "unprognostic (1.65e-3)" "unprognostic (2.27e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-1)" "unprognostic (5.76e-2)" "unprognostic (3.56e-2)" "unprognostic (2.34e-1)" "unprognostic (2.68e-2)" "unprognostic (2.05e-3)" 16.9 7.5 14.5 8.7 13.1 1.1 19.0 12.1 15.0 41.3 21.9 70.0 5.4 47.2 11.6 27.2 29.1 13.7 16.0 13.5 13.2 14.4 9.5 24.6 5.0 13.6 14.9 14.8 33.6 2.6 6.8 14.5 14.0 39.7 4.6 8.9 20.7 25.0 99.2 24.9 19.8 23.1 12.8 6.4 28.3 9.6 17.1 13.1 12.9 35.7 13.8 43.4 42.5 12.3 14.3 21.2 81.5 52.8 5.3 1.1 4.5 44.6 29.3 46.1 73.3 50.4 14.8 0.6 83.6 57.5 10.8 100.7 52.9 83.2 36.3 0.6 30.9 0.2 12.7 44.8 106.1 0.3 2.3 32.2 75.6 6.0 36.0 9.3 41.9 11.3 7.4 0.0 12.3 5.8 2.9 1.0 39.2 42.3 1.4 6.2 2.1 0.3 32.9 20.6 20.9 13.6 21.1 0.1 1.1 50.3 14.9 13.0 0.0 1.0 19.1 0.4 12.5 7.5 5.2 0.4 0.4 1.7 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.2 0.0 0.2 0.2 0.0 14.5 13.1 12.1 15.0 13.5 13.2 13.6 14.9 14.0 12.8 17.1 12.3 36.5 32.1 11.7 13.4 0.9 17.5 53.6 18.8 12.0 2.6 7.6 12.4 8.6 2.8 13.2 3.7 33.3 0.4 0.4 0.1 0.0 3.5 25.1 20.2 52.1 34.7 1.8 2.7 6.9 24.6 0.7 23.0 1.1 12.6 1.3 1.0 14.6 8.2 6.3 5.0 10.7 0.0 0.0 0.3 8.8 91.5 15.5 1.9 7.2 87.1 0.6 11.4 0.0 23.1 3.3 5.9 0.0 7.2 0.4 36.0 0.0 0.5 15.5 18.0 13.1 14.5 19.2 13.1 10.1 13.1 12.4 0.4 1.5 27.2 0.0 59.0 NYAP1 "C7orf51, FLJ37538, KIAA1486L" ENSG00000166924 "Neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1" Q6ZVC0 7 100483927-100494802 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;pituitary gland: 22.0" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Bipolar cells: 6.2;Excitatory neurons: 11.1;Granulosa cells: 5.6;Horizontal cells: 13.5;Inhibitory neurons: 10.3" "Cancer enhanced" "Detected in some" "glioma: 4.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 7.8;HUVEC TERT2: 3.9;SH-SY5Y: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022251 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Golgi apparatus" "HPA022251: AB_1848915" "unprognostic (6.59e-4)" "unprognostic (2.67e-2)" "unprognostic (1.82e-2)" "unprognostic (2.51e-4)" "unprognostic (2.89e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" "unprognostic (4.86e-2)" "unprognostic (2.54e-2)" "unprognostic (2.49e-3)" "unprognostic (1.81e-1)" "unprognostic (3.25e-1)" "unprognostic (1.20e-1)" "unprognostic (3.06e-2)" "unprognostic (4.31e-1)" "unprognostic (8.65e-2)" 2.1 2.5 6.4 0.3 8.4 0.1 1.6 0.0 22.5 2.9 0.0 1.3 0.2 4.6 0.0 1.1 2.2 0.2 0.7 11.4 2.9 1.9 0.4 0.3 0.1 6.6 0.6 5.3 0.9 0.0 22.0 0.3 6.8 2.0 0.1 1.9 0.9 0.9 0.1 1.4 0.8 0.5 0.0 0.8 0.8 9.1 2.0 0.1 0.7 0.1 0.0 0.6 2.0 8.2 0.0 1.1 3.0 1.4 2.0 1.2 0.2 0.1 1.0 0.1 0.4 0.4 0.2 0.0 1.0 0.3 7.8 0.1 0.6 0.1 0.0 1.4 0.2 0.1 0.3 0.2 1.4 0.0 0.8 1.3 0.0 0.4 0.5 0.3 3.9 0.2 0.5 0.1 0.0 0.3 0.0 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.9 9.4 0.3 0.2 1.0 1.1 0.1 0.0 1.4 0.0 1.9 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 8.4 0.0 22.5 11.4 2.9 6.6 0.6 6.8 0.0 2.0 8.2 3.2 0.0 0.0 9.4 0.0 0.1 0.2 0.1 0.6 6.2 0.3 1.9 1.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.2 0.4 1.4 0.0 0.8 11.1 0.0 0.0 0.9 0.0 0.4 0.0 5.6 0.7 0.0 0.1 13.5 10.3 0.1 0.0 0.0 0.7 0.7 2.5 0.1 0.0 2.8 0.0 3.3 0.0 2.5 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.1 0.2 1.0 0.0 0.5 0.7 1.3 2.6 0.2 0.1 0.0 0.1 0.8 0.0 0.0 ODF3L1 MGC48986 ENSG00000182950 "Outer dense fiber of sperm tails 3 like 1" Q8IXM7 15 75724041-75727688 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 22.6" "Cell type enriched" "Detected in some" 9 "Early spermatids: 111.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.0;HeLa: 1.2;U-87 MG: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (6.24e-2)" "unprognostic (1.97e-2)" "unprognostic (4.58e-2)" "unprognostic (8.42e-2)" "unprognostic (2.08e-2)" "unprognostic (1.41e-1)" "unprognostic (2.77e-1)" "unprognostic (1.56e-1)" "unprognostic (1.99e-1)" "unprognostic (2.74e-1)" "unprognostic (7.55e-4)" "unprognostic (9.65e-2)" "unprognostic (9.96e-3)" "unprognostic (6.40e-2)" "unprognostic (4.14e-2)" "unprognostic (8.94e-3)" "unprognostic (1.45e-2)" 1.4 0.1 0.3 0.3 0.2 0.3 1.1 1.3 0.4 0.6 0.4 1.4 0.5 1.2 0.1 1.2 1.0 2.6 1.1 0.4 0.1 0.2 1.1 1.6 0.1 0.1 0.5 0.2 0.4 0.1 1.1 0.2 0.1 0.4 0.4 0.0 0.1 0.1 0.1 1.7 0.8 0.9 0.0 0.3 1.7 22.6 0.2 0.6 1.4 0.0 0.1 0.9 0.2 0.1 0.0 1.0 0.3 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.2 0.9 0.0 0.0 0.1 0.0 0.9 0.0 0.6 0.0 0.7 0.4 0.0 1.2 0.2 0.2 0.0 0.0 0.6 0.0 0.2 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 1.3 0.4 0.4 0.1 0.1 0.5 0.1 0.0 0.2 0.1 0.1 0.0 1.1 0.0 0.4 6.1 9.7 0.9 0.0 0.0 0.6 0.3 0.0 0.0 2.5 0.0 0.0 1.6 0.1 0.7 0.0 0.3 111.2 2.7 0.5 0.3 0.0 0.0 0.1 0.0 0.9 2.1 1.5 1.8 0.0 0.2 1.1 0.3 0.4 0.0 0.0 1.2 0.0 0.0 2.7 11.9 0.0 1.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.7 0.8 0.9 1.6 0.7 0.3 0.0 6.6 2.7 1.0 8.0 0.4 0.0 6.5 1.9 0.4 0.1 0.5 4.1 OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936552 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 202.6;skin 1: 94.8" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Basal keratinocytes: 125.0;Muller glia cells: 91.1;Oligodendrocyte precursor cells: 124.7;Suprabasal keratinocytes: 118.1" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.7" "Group enriched" "Detected in many" 26 "granulocytes: 49.7;T-cells: 17.0" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;ASC diff: 23.4;BJ hTERT+: 18.5;SH-SY5Y: 24.3;U-2 OS: 28.7;WM-115: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA 2700000 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" 36.8 30.7 130.8 3.4 134.5 0.2 25.0 118.5 202.6 17.2 80.7 4.8 2.1 16.7 4.5 5.6 11.1 6.7 10.1 134.0 127.3 9.2 41.9 10.1 7.9 152.5 168.8 9.7 11.2 9.6 19.1 7.1 162.0 10.1 1.1 24.6 10.0 13.4 1.8 94.8 3.8 6.7 130.0 2.5 2.2 10.7 123.2 16.5 13.2 1.0 4.8 3.0 14.1 120.7 0.0 3.7 3.0 25.6 23.4 14.3 1.7 5.6 18.5 1.2 1.5 0.3 2.4 0.1 2.3 4.2 2.1 1.5 9.8 1.7 0.1 0.1 2.1 0.0 0.2 0.3 0.1 0.0 4.3 7.5 1.5 0.1 0.2 0.7 0.1 4.8 0.3 0.3 0.0 8.2 0.3 0.2 15.8 2.5 0.0 0.1 0.0 0.0 0.0 0.9 0.1 24.3 0.9 0.1 5.2 9.7 0.9 0.0 0.3 10.5 28.7 0.1 0.1 0.0 0.0 0.0 0.3 0.0 25.6 21.2 0.0 49.7 6.2 0.0 6.6 0.0 7.0 5.5 0.0 0.0 13.5 8.9 0.5 1.2 0.0 0.1 17.0 2.9 130.8 134.5 118.5 202.6 134.0 127.3 152.5 168.8 162.0 130.0 123.2 120.7 12.9 0.0 0.0 108.4 0.3 125.0 4.7 5.9 8.6 4.9 6.9 13.8 0.8 7.2 0.4 7.3 0.0 0.1 1.0 0.1 1.9 0.9 8.6 0.9 2.2 4.3 1.2 0.4 27.3 2.4 0.0 17.2 0.0 1.0 4.5 6.5 1.4 24.7 0.3 1.7 51.0 0.2 2.0 0.3 32.6 52.8 13.7 0.6 17.8 15.0 0.4 91.1 7.2 124.7 3.5 4.1 0.0 9.8 0.5 7.9 0.0 0.2 0.2 3.7 0.0 7.4 24.3 3.0 10.4 1.4 118.1 0.1 7.7 0.6 0.1 2.9 OLFML2A FLJ00237 ENSG00000185585 "Olfactomedin like 2A" Q68BL7 9 124777133-124814885 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 40.1;Endothelial cells: 21.2;Fibroblasts: 29.0;Skeletal myocytes: 63.0;Smooth muscle cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 160.0;GAMG: 34.0;HeLa: 39.8;hTERT-RPE1: 38.0;WM-115: 64.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021180, HPA022254" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 240000 "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA021180: AB_1854790, HPA022254: AB_1854791" "unprognostic (1.12e-1)" "unprognostic (3.07e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-1)" "unprognostic (4.01e-2)" "unprognostic (1.27e-1)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (1.26e-3)" "unprognostic (7.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (3.73e-5)" "unprognostic (5.72e-3)" "unprognostic (3.30e-2)" "unprognostic (7.91e-2)" "unprognostic (1.05e-2)" 15.4 2.9 2.6 2.7 3.1 0.3 11.1 2.2 4.6 25.0 3.3 29.9 3.3 25.3 2.8 8.2 6.4 4.8 16.4 2.2 2.4 4.3 0.7 10.5 2.4 2.8 2.1 12.0 4.8 4.6 2.8 7.0 2.8 7.4 6.2 2.2 7.0 12.2 10.8 16.0 6.9 16.0 2.1 32.8 5.5 1.1 2.6 3.1 19.1 10.0 3.7 17.6 14.6 2.1 0.8 14.6 1.2 0.4 16.8 160.0 0.1 1.8 8.2 3.5 3.5 0.2 2.2 0.0 3.4 0.1 34.0 25.5 0.4 0.8 4.0 0.0 0.1 0.0 39.8 0.1 0.9 0.0 0.1 11.3 2.7 10.2 1.4 38.0 0.0 0.0 0.0 0.2 1.8 0.4 0.0 0.3 3.4 0.0 0.9 0.0 9.5 0.0 0.0 1.2 0.0 0.1 2.9 0.2 4.3 28.6 3.9 0.5 0.1 5.2 4.6 5.5 0.7 1.9 0.0 0.1 15.2 0.8 64.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.1 2.6 3.1 2.2 4.6 2.2 2.4 2.8 2.1 2.8 2.1 2.6 2.1 40.1 0.0 1.3 0.7 0.4 12.0 5.9 17.5 6.2 0.6 2.9 8.3 13.8 1.5 5.5 0.0 2.1 0.3 0.5 0.0 0.0 0.1 0.7 0.2 1.5 21.2 0.0 0.0 0.4 0.6 0.3 29.0 0.5 0.2 0.0 0.9 3.6 0.1 0.1 0.0 0.6 0.0 4.1 1.5 7.9 1.4 2.8 0.9 10.6 8.4 0.1 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.1 4.0 0.0 0.1 11.5 4.0 13.1 63.0 36.4 0.4 0.7 4.5 8.4 0.0 0.6 4.2 0.0 3.5 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 OR10V1 ENSG00000172289 "Olfactory receptor family 10 subfamily V member 1" Q8NGI7 11 59712916-59713845 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA060076 Uncertain NA NA "HPA060076: AB_2684198" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ORC6 ORC6L ENSG00000091651 "Origin recognition complex subunit 6" Q9Y5N6 16 46689643-46698394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;lymphoid tissue: 7.4;testis: 9.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 56.7;Spermatocytes: 102.6;Spermatogonia: 108.9;Theca cells: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016330, HPA072587" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB016330: AB_670295, HPA072587: AB_2686537" "unprognostic (3.47e-2)" "unprognostic (8.99e-3)" "unprognostic (2.92e-1)" "unprognostic (4.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.19e-2)" "unprognostic (3.15e-6)" "unprognostic (1.36e-2)" "prognostic unfavorable (3.53e-4)" "prognostic favorable (1.48e-4)" "unprognostic (1.50e-4)" "unprognostic (3.97e-2)" "unprognostic (3.90e-14)" "unprognostic (2.08e-1)" "unprognostic (4.24e-1)" "unprognostic (2.79e-1)" "unprognostic (5.98e-2)" 0.3 0.7 2.0 2.2 1.6 10.3 0.6 1.5 1.9 0.7 1.0 1.7 1.5 0.8 1.1 4.1 0.4 0.6 1.5 1.9 1.8 0.4 0.9 0.6 7.4 1.5 1.9 0.4 0.3 0.7 0.6 3.3 1.7 0.3 1.9 0.3 0.7 0.2 0.1 1.1 1.5 1.0 1.6 2.4 0.8 9.6 1.8 6.2 0.5 0.3 7.3 1.2 1.3 1.8 28.6 27.4 43.7 33.9 5.4 6.8 31.6 54.2 20.2 59.3 30.9 39.3 18.0 35.6 27.1 10.5 29.1 29.9 57.9 15.1 50.4 17.2 46.4 27.9 13.2 40.1 6.6 46.5 23.7 1.8 2.6 32.4 17.1 9.3 20.0 30.1 36.0 17.4 35.9 26.9 65.6 60.7 48.1 20.7 76.0 78.6 80.6 35.8 14.9 9.8 52.2 30.4 24.5 29.8 18.1 34.9 15.6 37.9 11.6 53.7 34.6 33.6 51.8 12.5 18.9 123.2 22.2 29.5 40.1 0.0 0.3 0.3 0.9 0.7 0.4 0.7 0.5 0.5 0.6 1.4 0.8 0.3 0.0 0.8 0.8 1.0 1.2 0.7 2.0 1.6 1.5 1.9 1.9 1.8 1.5 1.9 1.7 1.6 1.8 1.8 1.6 3.2 14.5 1.0 8.8 6.6 2.2 3.6 8.6 6.6 4.1 5.8 3.7 1.5 6.3 5.5 4.2 39.3 6.0 9.5 1.9 2.5 13.2 6.5 7.5 4.3 1.8 45.4 6.3 0.7 40.9 8.0 7.1 9.4 1.3 56.7 0.7 9.9 15.7 11.8 2.7 12.4 6.1 3.8 11.9 8.9 2.8 7.7 33.8 2.8 1.2 2.5 2.1 0.0 2.0 2.1 1.4 3.4 18.5 2.6 2.3 1.0 10.7 10.2 0.0 5.1 7.3 102.6 108.9 16.9 6.0 10.9 7.5 47.5 14.4 2.7 OSBP OSBP1 ENSG00000110048 "Oxysterol binding protein" P22059 11 59574398-59615774 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039227, HPA043625" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 70000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039227: AB_2676401, HPA043625: AB_2678587" "unprognostic (3.09e-2)" "unprognostic (3.76e-2)" "prognostic favorable (2.08e-5)" "unprognostic (7.80e-3)" "unprognostic (7.32e-2)" "unprognostic (2.79e-2)" "unprognostic (2.13e-1)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (7.42e-2)" "unprognostic (1.42e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.08e-7)" "unprognostic (1.25e-1)" "unprognostic (9.00e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" 19.6 41.7 14.1 15.5 15.2 27.2 27.4 15.3 18.9 24.7 18.4 26.8 29.4 20.0 31.6 19.6 22.4 19.5 25.5 15.0 15.6 42.8 57.6 18.5 17.8 15.4 16.7 22.4 37.3 44.9 16.1 22.9 16.7 25.9 28.3 15.9 30.1 27.0 57.7 26.6 25.5 21.2 14.0 15.6 27.8 18.0 15.7 24.0 32.3 43.8 23.7 19.6 17.1 15.1 40.9 33.6 24.7 33.2 56.5 52.4 26.8 32.9 42.3 38.4 34.4 38.1 40.2 41.1 42.7 37.9 47.2 41.4 45.4 43.5 43.0 40.0 20.9 28.1 25.1 25.8 60.2 36.2 52.9 40.4 52.8 36.2 94.4 40.0 41.7 38.3 48.6 37.3 34.5 19.0 34.0 26.2 28.0 59.5 32.7 32.5 39.8 28.6 45.6 47.0 28.5 20.3 38.6 47.7 46.0 33.6 66.9 22.7 45.8 32.7 22.8 49.5 22.3 51.9 45.2 41.4 37.0 25.6 26.8 1.7 1.6 1.5 2.8 1.4 2.6 2.2 2.9 2.3 1.6 1.6 2.6 2.1 1.5 2.2 1.3 4.0 1.3 1.1 14.1 15.2 15.3 18.9 15.0 15.6 15.4 16.7 16.7 14.0 15.7 15.1 29.2 25.6 9.0 14.7 18.9 39.6 16.4 13.7 29.6 23.8 38.0 27.1 34.1 32.9 19.0 27.6 22.9 14.2 31.1 34.0 7.9 14.0 8.8 37.9 52.7 21.8 30.0 10.5 25.6 18.6 14.7 21.1 22.4 43.8 27.9 21.8 15.4 67.1 16.0 26.9 22.9 40.0 8.2 12.9 16.9 14.5 15.8 17.9 14.2 12.2 9.6 15.7 18.6 18.1 23.3 20.2 20.5 19.9 32.2 31.2 34.6 21.0 27.8 21.7 6.6 28.4 19.3 25.1 14.5 27.0 47.3 30.8 20.0 43.5 28.4 26.4 OSR1 ODD ENSG00000143867 "Odd-skipped related transcription factor 1" Q8TAX0 2 19351485-19358623 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 81.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 35.8;Leydig cells: 133.6;Peritubular cells: 45.9;Smooth muscle cells: 21.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.9" "Region enhanced" "Detected in some" "thalamus: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 11 "U-2197: 101.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015525 Uncertain NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA015525: AB_1854822" "unprognostic (1.71e-3)" "unprognostic (1.23e-1)" "unprognostic (6.85e-4)" "unprognostic (1.42e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-2)" "unprognostic (8.47e-4)" "unprognostic (2.79e-1)" "unprognostic (1.91e-1)" "unprognostic (6.87e-2)" "unprognostic (3.56e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-3)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (1.62e-1)" 38.6 2.4 0.4 3.5 0.8 0.0 22.4 0.3 1.7 16.7 1.8 23.1 1.4 10.3 0.3 3.6 8.1 5.9 13.4 1.6 0.0 1.5 0.5 17.0 0.5 0.3 0.1 6.1 2.8 0.2 2.7 3.3 0.2 13.9 2.0 0.0 31.5 3.7 3.0 10.8 11.1 11.3 0.2 0.1 9.7 5.4 3.4 0.6 10.2 3.5 0.1 81.4 12.3 0.0 0.0 2.4 0.1 4.7 3.2 9.2 0.0 6.0 2.8 5.6 2.8 0.0 0.1 0.0 0.0 8.5 2.7 0.0 3.0 1.4 1.4 0.0 0.2 0.0 0.1 3.5 4.0 0.0 0.2 4.6 0.0 5.2 6.9 4.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.1 0.0 3.6 5.0 0.0 0.2 0.0 0.6 1.9 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 1.3 0.4 101.8 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.3 1.7 1.6 0.0 0.3 0.1 0.2 0.2 3.4 0.0 1.2 0.0 0.5 0.0 0.0 4.7 1.0 1.7 0.6 0.0 1.0 6.1 7.2 0.0 1.1 3.7 0.0 0.5 0.1 0.1 0.0 1.3 0.7 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.4 35.8 0.0 0.1 1.3 1.2 0.0 0.0 0.9 0.0 0.0 0.3 4.1 0.0 4.9 3.8 133.6 0.3 3.6 2.8 0.0 0.0 0.0 0.0 0.1 0.4 0.1 45.9 0.0 0.4 0.0 2.9 0.3 0.0 0.0 1.3 21.4 0.4 0.1 0.3 4.1 0.4 0.7 0.8 0.2 1.1 OSTF1 "bA235O14.1, OSF, SH3P2" ENSG00000134996 "Osteoclast stimulating factor 1" Q92882 9 75088514-75147265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 329.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 302.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020514 Approved Supported Cytosol NA NA 580000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA020514: AB_2670461" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (7.54e-2)" "prognostic favorable (3.67e-5)" "unprognostic (1.36e-1)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (1.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-3)" "unprognostic (3.76e-1)" "unprognostic (7.89e-2)" "unprognostic (6.36e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" 44.3 36.9 27.8 65.7 35.0 56.3 34.9 32.0 37.2 34.1 25.4 42.5 38.2 22.7 38.2 104.8 20.0 42.8 32.0 28.3 33.2 34.6 57.7 56.4 74.9 31.0 32.5 16.0 19.4 72.1 19.1 69.9 33.1 22.7 45.8 12.3 38.5 19.6 9.5 63.1 47.8 28.8 30.8 87.0 40.6 18.0 31.0 47.8 29.0 16.0 85.0 55.3 53.9 35.1 69.1 16.0 7.7 11.2 45.4 41.7 81.3 71.9 46.9 26.9 24.4 8.2 50.8 70.9 35.3 59.2 34.6 111.8 12.9 51.9 77.0 302.0 16.0 39.3 24.8 42.5 36.7 71.5 141.6 29.1 49.2 31.6 21.8 23.7 91.2 59.4 13.4 158.4 65.4 35.9 107.5 44.8 14.5 161.5 30.8 20.1 52.3 63.0 57.0 97.1 6.5 0.6 53.1 74.1 36.2 58.2 97.4 79.9 86.4 55.8 19.4 108.3 30.8 30.1 52.5 26.7 67.1 81.9 46.4 359.5 177.7 464.8 158.6 199.3 169.6 101.2 110.5 131.5 148.7 87.4 62.1 109.8 495.2 168.4 256.8 110.6 163.0 283.0 27.8 35.0 32.0 37.2 28.3 33.2 31.0 32.5 33.1 30.8 31.0 35.1 113.4 22.4 24.4 8.1 90.8 82.2 61.2 78.2 61.5 2.9 38.6 23.2 7.8 28.6 51.2 33.1 6.2 125.5 162.1 64.8 76.3 49.7 11.9 42.8 59.4 60.5 27.2 23.3 32.0 52.3 252.9 42.1 31.1 51.1 137.6 4.2 71.7 32.2 233.1 10.1 12.6 31.9 69.2 167.4 181.5 6.0 23.9 155.7 76.5 43.1 329.9 6.0 268.8 30.2 67.3 60.5 97.7 15.4 83.2 34.1 64.1 63.0 27.3 8.6 19.7 15.9 45.0 6.7 17.8 141.4 114.5 133.9 163.8 37.6 38.2 91.6 OTOGL "C12orf64, FLJ90579" ENSG00000165899 "Otogelin like" Q3ZCN5 12 80099537-80380880 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 1.9;kidney: 5.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 51.2;Oligodendrocyte precursor cells: 42.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.3;U-87 MG: 2.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "basal ganglia: 4.2" "HPA040364, HPA053392" Uncertain Approved Cytosol "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA040364: AB_10795365, HPA053392: AB_2682135" "unprognostic (2.43e-1)" "unprognostic (2.78e-2)" "unprognostic (2.55e-2)" "unprognostic (1.50e-1)" "unprognostic (5.99e-2)" "unprognostic (3.10e-1)" "unprognostic (3.34e-3)" "unprognostic (4.76e-2)" "unprognostic (2.72e-2)" "unprognostic (4.52e-2)" "unprognostic (2.79e-2)" "unprognostic (1.57e-1)" "unprognostic (1.95e-5)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.79e-2)" "unprognostic (2.04e-2)" 0.1 0.0 0.5 0.0 0.7 0.0 0.1 0.0 1.0 0.1 0.0 0.4 0.0 0.1 0.1 0.1 0.1 0.1 1.9 0.3 0.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.5 0.1 0.1 0.1 0.5 0.0 0.1 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.3 0.0 0.0 2.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 1.4 0.1 0.1 0.2 0.0 0.0 51.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.0 0.0 0.0 42.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 OTUD1 "DUBA7, OTDC1" ENSG00000165312 "OTU deubiquitinase 1" Q5VV17 10 23439075-23442377 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 149.0;Langerhans cells: 219.1;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 38.1;HaCaT: 36.5;SiHa: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038503, HPA038504" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA038503: AB_2676049, HPA038504: AB_10672712" "unprognostic (1.84e-1)" "unprognostic (2.80e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.56e-1)" "unprognostic (1.29e-2)" "unprognostic (3.18e-3)" "unprognostic (2.41e-1)" "unprognostic (7.77e-2)" "unprognostic (4.10e-2)" "unprognostic (1.80e-2)" "unprognostic (1.32e-1)" "prognostic favorable (6.61e-7)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-2)" 13.0 11.7 8.0 10.2 8.4 60.4 10.3 9.5 10.2 8.4 8.4 8.7 6.8 10.2 6.8 7.8 11.2 9.7 43.4 8.7 9.0 19.7 7.6 19.7 14.4 8.3 8.0 13.6 6.9 19.4 8.0 12.1 7.6 8.8 7.6 5.9 6.7 7.6 29.4 20.9 8.2 9.4 8.4 13.7 22.9 7.5 9.2 6.8 13.3 22.6 12.5 11.9 7.6 9.2 4.8 2.3 2.4 1.1 9.3 4.6 3.2 1.9 4.2 4.4 4.0 0.9 38.1 2.2 4.1 2.4 1.5 36.5 2.5 4.5 2.9 17.4 7.1 0.1 5.7 1.5 8.0 0.4 3.2 4.8 19.4 1.3 6.1 3.9 1.5 2.2 0.5 15.1 2.5 2.3 1.5 1.4 1.9 2.7 1.3 2.4 10.8 2.2 5.8 4.0 1.1 2.6 23.4 4.1 11.3 6.3 1.7 3.3 2.7 2.5 3.7 7.0 0.8 7.6 15.0 1.1 3.8 1.5 1.0 2.5 0.5 1.0 0.3 0.6 0.3 0.7 0.5 0.3 0.3 1.2 0.4 0.6 1.3 0.0 1.9 0.2 1.3 0.2 8.0 8.4 9.5 10.2 8.7 9.0 8.3 8.0 7.6 8.4 9.2 9.2 17.3 67.3 11.5 3.3 55.9 32.0 7.1 5.0 13.6 20.1 12.3 9.1 149.0 7.2 4.9 5.5 2.1 3.3 9.6 47.2 11.7 6.0 8.0 35.0 44.5 25.6 6.0 13.5 4.3 7.1 3.2 20.8 47.4 33.8 5.7 10.4 16.4 10.1 51.0 53.8 4.8 77.9 10.2 68.2 219.1 7.6 6.5 105.7 33.8 8.4 9.3 33.8 10.3 4.0 6.5 10.1 16.3 13.2 50.0 7.7 8.0 25.1 9.8 26.2 6.6 82.2 19.4 7.2 4.7 15.1 30.5 7.9 16.5 7.5 24.3 10.9 P2RX1 P2X1 ENSG00000108405 "Purinergic receptor P2X 1" P51575 17 3896592-3916476 "Predicted membrane proteins" "Apoptosis, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.0;pancreas: 65.1;urinary bladder: 75.5" "Cell type enriched" "Detected in some" 5 "granulocytes: 185.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 46.3" "Group enriched" "Detected in many" 30 "dendritic cells: 15.1;granulocytes: 23.5;monocytes: 46.3" "Cell line enhanced" "Detected in some" "HEL: 13.8;HMC-1: 8.4;Karpas-707: 16.8;THP-1: 14.7;U-937: 7.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.3" HPA057678 Approved "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Endoplasmic reticulum" "HPA057678: " "unprognostic (1.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.65e-1)" "unprognostic (3.54e-2)" "unprognostic (7.34e-3)" "unprognostic (9.89e-5)" "unprognostic (1.77e-2)" "unprognostic (6.15e-3)" "unprognostic (2.98e-1)" "unprognostic (2.52e-3)" "unprognostic (1.90e-1)" "unprognostic (2.20e-2)" "unprognostic (4.47e-3)" "unprognostic (2.60e-1)" "unprognostic (5.58e-2)" "unprognostic (4.29e-1)" "unprognostic (1.09e-2)" 9.8 2.0 0.5 4.4 0.8 42.0 1.5 0.8 0.7 7.7 0.4 13.4 9.3 7.3 1.8 23.0 3.9 2.0 2.0 0.5 0.7 1.0 0.7 4.8 2.9 0.8 0.9 2.1 65.1 0.1 0.3 3.8 0.8 10.7 9.2 0.1 1.6 34.1 0.5 5.9 9.0 6.0 0.7 13.0 2.8 2.6 0.6 2.0 0.4 0.3 3.2 75.5 8.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.2 0.1 1.1 1.8 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.1 3.3 0.0 0.4 0.0 2.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.1 7.4 0.0 0.0 10.8 11.9 0.0 20.4 0.0 0.4 0.0 0.0 5.9 0.9 0.0 0.0 23.5 0.0 46.3 15.1 0.0 8.2 0.5 0.8 0.8 0.7 0.5 0.7 0.8 0.9 0.8 0.7 0.6 1.0 0.1 3.2 4.2 0.7 15.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.0 0.1 8.9 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 18.5 0.3 2.0 0.1 0.9 0.5 0.0 185.4 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.0 5.1 2.4 0.2 0.0 22.5 0.0 1.0 7.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 36.0 0.0 0.0 0.1 0.7 0.0 0.0 0.4 3.4 0.0 0.1 0.1 0.9 0.0 1.8 0.5 0.3 0.0 PAAF1 "FLJ11848, Rpn14, WDR71" ENSG00000175575 "Proteasomal ATPase associated factor 1" Q9BRP4 11 73876699-73931114 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 130.1" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 112.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039952, HPA040020" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA039952: AB_10793925, HPA040020: AB_2676802" "unprognostic (3.13e-1)" "unprognostic (1.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-1)" "unprognostic (2.05e-1)" "unprognostic (2.13e-2)" "unprognostic (4.51e-2)" "unprognostic (1.33e-1)" "unprognostic (4.58e-3)" "unprognostic (1.74e-1)" "unprognostic (4.48e-1)" "unprognostic (2.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.23e-1)" "unprognostic (2.73e-1)" "unprognostic (4.42e-1)" 17.3 29.0 85.2 11.3 92.6 9.0 17.6 82.3 130.1 19.4 68.8 25.0 11.8 16.6 23.8 14.4 19.6 12.0 25.2 80.3 85.9 23.9 21.9 12.6 12.6 88.0 88.6 24.6 22.2 19.1 25.8 11.7 87.3 22.0 16.3 46.4 15.4 19.8 19.8 19.2 14.3 15.5 85.4 16.3 18.5 30.3 85.7 15.9 18.8 7.5 17.2 21.7 16.3 101.2 13.5 30.6 27.2 21.3 28.9 29.6 15.5 22.6 25.9 35.3 25.0 60.2 10.4 40.4 34.4 23.2 32.8 30.2 33.5 27.2 52.2 30.4 20.8 41.4 28.0 50.3 34.6 39.1 15.3 30.5 41.7 38.8 47.2 28.4 27.0 32.1 50.7 33.7 33.2 26.3 34.5 40.5 12.7 71.0 23.7 31.6 72.6 66.5 26.5 22.9 28.8 33.8 26.8 17.7 70.6 25.4 53.1 21.8 19.7 24.8 15.7 35.3 22.3 41.3 50.3 82.2 17.4 25.0 26.5 53.4 26.2 32.3 26.8 17.2 29.5 40.8 28.7 27.3 34.4 36.1 37.0 31.7 2.2 32.4 6.3 24.8 36.8 27.9 85.2 92.6 82.3 130.1 80.3 85.9 88.0 88.6 87.3 85.4 85.7 101.2 9.0 3.2 12.5 40.1 11.5 4.7 11.6 27.3 6.8 50.4 6.8 9.1 19.6 8.6 15.6 16.5 112.6 33.5 9.5 5.5 13.7 15.9 38.4 10.7 12.2 9.8 3.6 20.2 17.4 13.8 4.8 11.5 6.6 9.4 19.6 30.1 11.7 13.6 18.8 47.1 23.7 7.7 20.3 9.5 6.6 22.6 16.8 9.5 14.2 14.0 16.3 37.6 18.6 24.6 55.5 7.3 5.7 18.0 15.3 9.6 12.0 53.5 14.1 51.7 6.6 18.2 12.5 48.9 28.6 9.6 8.1 18.3 9.8 29.9 10.3 8.0 PABPC1L2B RBM32B ENSG00000184388 "Poly(A) binding protein cytoplasmic 1 like 2B" Q5JQF8 X 73002939-73006106 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.2;pituitary gland: 2.1;prostate: 2.7;salivary gland: 2.1;testis: 1.6" "Cell type enhanced" "Detected in some" "Early spermatids: 1.7;Excitatory neurons: 2.2;Inhibitory neurons: 2.7;Oligodendrocytes: 1.7" "Cancer enriched" "Detected in single" 23 "prostate cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.1" HPA041573 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA041573: AB_2677556" "unprognostic (1.73e-1)" "unprognostic (2.26e-1)" "unprognostic (3.31e-1)" 0.0 0.6 2.6 0.0 1.7 0.0 0.0 0.2 5.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.3 3.4 0.0 0.0 0.0 0.0 1.6 1.0 0.0 0.0 0.0 2.1 0.0 0.8 2.7 0.0 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 0.2 5.2 1.3 3.4 1.6 1.0 0.8 0.1 2.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PABPC4L ENSG00000254535 "Poly(A) binding protein cytoplasmic 4 like" P0CB38 4 134196333-134201789 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 10.3" "Cell type enhanced" "Detected in some" "Adipocytes: 5.3;Endometrial ciliated cells: 7.4;Endometrial stromal cells: 5.7;Fibroblasts: 5.5;Glandular and luminal cells: 12.2;Leydig cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 11.4;HeLa: 15.8;REH: 8.1;RH-30: 8.5;U-2 OS: 8.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 20: HeLa - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.00e-1)" "unprognostic (3.53e-2)" "unprognostic (1.96e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (2.55e-3)" "unprognostic (1.58e-1)" "unprognostic (3.63e-1)" "unprognostic (9.05e-3)" "unprognostic (2.97e-1)" "unprognostic (9.52e-2)" "unprognostic (6.44e-2)" "prognostic favorable (1.11e-5)" "unprognostic (4.41e-3)" "unprognostic (1.82e-1)" "unprognostic (1.22e-1)" "unprognostic (4.14e-3)" 1.5 0.4 0.6 0.5 0.7 0.0 0.8 0.5 0.8 2.4 0.5 0.4 0.3 3.7 1.4 0.7 2.0 1.1 1.7 0.4 0.5 1.0 0.1 0.5 0.2 0.5 0.5 2.2 0.3 5.3 0.3 10.3 0.6 2.9 0.3 0.0 2.1 4.2 0.2 0.3 0.3 2.4 0.5 0.1 0.3 0.5 1.1 0.9 2.0 0.9 0.5 0.7 0.8 0.6 0.0 0.1 2.8 0.0 0.0 0.0 0.0 3.4 2.3 1.6 1.9 0.0 0.0 0.0 3.5 0.0 0.0 0.3 11.4 0.1 2.3 0.0 2.6 4.5 15.8 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.6 0.0 2.3 0.0 1.3 0.0 0.1 0.0 0.0 0.0 1.4 8.1 8.5 0.0 0.5 0.0 3.4 0.9 0.0 0.7 0.2 2.9 0.0 1.5 0.2 2.9 8.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.8 0.4 0.5 0.5 0.5 0.6 0.5 1.1 0.6 5.3 3.2 1.1 0.0 0.0 0.3 0.4 0.0 1.2 0.0 0.2 0.9 1.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.3 7.4 5.7 4.3 0.0 0.0 0.0 0.0 0.4 5.5 0.0 12.2 0.0 3.8 1.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 2.3 5.6 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 1.4 3.1 1.3 0.8 0.1 0.8 0.3 4.5 0.0 0.1 PACSIN1 SDPI ENSG00000124507 "Protein kinase C and casein kinase substrate in neurons 1" Q9BY11 6 34466061-34535229 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 149.3;retina: 64.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 76.1;Cone photoreceptor cells: 81.3;dendritic cells: 24.9;Excitatory neurons: 49.9;Horizontal cells: 69.0;Inhibitory neurons: 47.6;Rod photoreceptor cells: 89.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.8" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.8" "Cell line enhanced" "Detected in some" "MCF7: 12.1;RPMI-8226: 14.0;T-47d: 21.5;U-266/84: 16.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009929, HPA028852, HPA055491" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" "CAB009929: AB_2268057, HPA028852: AB_10602812, HPA055491: AB_2682834" "unprognostic (3.33e-1)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.72e-2)" "unprognostic (2.47e-3)" "unprognostic (2.14e-2)" "unprognostic (2.65e-1)" "unprognostic (1.74e-1)" "unprognostic (6.63e-2)" "unprognostic (3.95e-4)" "unprognostic (9.12e-2)" "unprognostic (3.02e-2)" "unprognostic (4.18e-2)" "unprognostic (9.90e-2)" "unprognostic (5.50e-2)" "unprognostic (9.33e-2)" 0.2 0.7 40.9 1.2 72.9 0.8 0.2 0.0 149.3 0.3 0.0 0.8 0.5 0.5 0.1 0.1 0.6 0.3 5.4 64.4 0.0 1.4 0.2 0.2 3.6 58.8 10.0 0.6 5.1 1.7 6.3 0.0 55.4 0.7 0.2 64.3 1.0 0.4 0.2 0.3 1.4 0.1 0.0 1.3 1.3 0.8 3.9 1.3 0.2 0.1 2.2 0.4 0.3 59.5 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 4.5 0.8 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 1.1 0.1 0.0 12.1 0.7 0.0 2.8 0.1 0.1 0.1 0.0 14.0 0.0 0.4 4.2 0.3 0.0 2.2 0.0 0.4 21.5 2.4 0.0 0.0 0.3 0.0 0.0 3.5 16.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.6 0.0 15.8 0.0 0.1 40.9 72.9 0.0 149.3 64.4 0.0 58.8 10.0 55.4 0.0 3.9 59.5 0.2 0.0 0.0 2.3 0.3 0.0 0.1 0.0 0.0 76.1 0.2 0.1 4.5 0.0 0.0 0.0 81.3 0.1 24.9 0.1 0.0 0.3 0.2 1.3 0.2 0.6 0.0 0.0 49.9 0.7 0.0 0.1 0.5 2.0 0.0 0.2 0.0 0.0 0.0 69.0 47.6 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 6.5 0.0 12.7 1.0 1.0 2.0 0.1 0.0 0.0 0.2 0.1 0.0 2.3 0.0 89.4 0.0 0.2 0.2 0.4 1.7 0.0 0.0 0.0 0.6 0.1 0.1 0.1 PAEP "GD, GdA, GdF, GdS, MGC138509, MGC142288, PAEG, PEP, PP14" ENSG00000122133 "Progestagen associated endometrial protein" P09466 9 135561756-135566955 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 94.1;endometrium 1: 256.0" "Cell type enriched" "Detected in some" 10 "Glandular and luminal cells: 10785.5" "Cancer enriched" "Detected in many" 8 "melanoma: 275.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.1;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.1" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016762, HPA020108, HPA029473" Enhanced "Secreted in female reproductive system" NA NA 120000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "CAB016762: , HPA020108: AB_1855595, HPA029473: AB_10610147" "unprognostic (3.39e-2)" "unprognostic (8.47e-3)" "unprognostic (6.84e-2)" "unprognostic (3.46e-2)" "unprognostic (3.20e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (1.27e-2)" "unprognostic (1.72e-1)" "unprognostic (3.95e-3)" "unprognostic (1.93e-3)" "prognostic unfavorable (0.00e+0)" "prognostic unfavorable (5.46e-4)" "unprognostic (4.24e-1)" "unprognostic (4.98e-2)" 0.1 0.2 0.2 1.1 0.4 1.6 0.5 0.7 0.7 94.1 2.0 0.1 1.0 256.0 0.9 0.2 4.8 0.3 0.1 0.4 0.4 0.1 0.1 0.5 0.6 0.3 0.2 0.7 0.0 0.0 0.0 27.2 0.2 2.7 0.1 0.4 0.4 44.8 0.6 2.1 0.8 0.1 0.1 0.3 6.0 0.7 0.4 0.0 0.3 0.0 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.0 0.9 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.6 1.6 2.2 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.2 2.9 0.2 0.0 0.3 0.0 0.7 0.5 0.0 0.0 0.2 0.2 0.3 0.0 0.2 0.4 0.2 0.1 0.2 21.0 0.6 0.3 0.2 0.0 0.0 1.0 0.2 0.1 0.8 2.2 0.1 0.2 0.2 0.2 3.1 0.3 0.2 0.2 0.2 0.1 0.2 0.3 0.2 0.1 0.4 0.3 0.3 1.4 0.3 0.3 0.5 0.1 0.1 0.2 0.4 0.7 0.7 0.4 0.4 0.3 0.2 0.2 0.1 0.4 1.0 0.0 0.0 0.5 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.9 0.6 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 613.5 1008.8 67.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 10785.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 144.0 0.0 0.0 0.0 0.0 0.0 86.5 0.0 0.0 0.0 PAIP2B KIAA1155 ENSG00000124374 "Poly(A) binding protein interacting protein 2B" Q9ULR5 2 71182738-71227103 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 181.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.0;Early spermatids: 95.1;Hepatocytes: 67.1;Proximal tubular cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 15.8;SCLC-21H: 23.1" "Low region specificity" "Detected in all" "HPA046784, HPA072371" Approved Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA046784: AB_2679804, HPA072371: AB_2686514" "unprognostic (8.70e-2)" "unprognostic (8.20e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.17e-5)" "unprognostic (4.56e-2)" "unprognostic (1.34e-1)" "unprognostic (9.67e-3)" "unprognostic (1.51e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.96e-12)" "unprognostic (1.63e-2)" "unprognostic (3.87e-1)" "unprognostic (1.21e-2)" "unprognostic (4.61e-2)" 2.4 1.6 131.5 1.8 159.1 1.3 4.5 108.3 176.8 3.1 66.3 3.8 3.7 2.9 1.8 6.1 7.2 1.1 23.0 94.7 116.5 10.3 18.1 2.7 2.1 134.9 136.6 11.5 54.2 6.0 2.2 0.6 143.0 4.8 3.7 27.7 37.9 3.5 48.5 16.4 2.7 1.7 132.8 2.2 10.5 2.2 130.3 2.4 11.6 26.7 4.6 2.8 4.0 181.5 2.5 0.6 1.0 3.6 0.4 0.5 4.4 0.3 0.1 0.3 0.2 0.9 1.0 3.2 0.6 0.0 2.4 2.0 6.1 3.7 1.2 1.7 5.0 3.1 0.4 0.1 1.6 0.8 0.2 0.6 3.3 0.2 3.6 0.9 0.6 7.2 5.5 3.0 0.2 3.2 1.0 1.7 2.6 5.8 2.3 0.0 10.5 15.8 1.9 1.7 23.1 1.3 2.6 1.7 1.1 5.5 7.5 0.2 0.1 0.3 1.9 1.9 1.0 6.1 5.5 3.9 0.2 1.1 0.5 0.5 0.3 0.5 1.0 0.4 1.2 2.5 1.3 1.0 0.4 2.6 2.1 1.9 0.2 0.8 0.4 2.3 0.6 0.6 131.5 159.1 108.3 176.8 94.7 116.5 134.9 136.6 143.0 132.8 130.3 181.5 3.3 3.2 4.5 5.2 9.9 7.8 7.0 4.0 5.7 11.3 14.8 8.8 86.0 12.8 2.7 7.3 6.2 3.2 13.2 2.7 21.5 4.9 95.1 18.4 3.9 3.9 41.5 15.6 4.2 41.3 9.2 4.7 11.2 17.5 1.3 7.5 7.1 67.1 1.9 6.7 4.6 6.3 14.2 3.2 1.6 30.0 5.3 2.6 14.2 2.8 2.4 12.3 4.1 2.5 31.9 10.4 4.0 5.3 29.9 9.4 1.3 56.9 15.5 43.3 0.0 9.3 4.0 32.9 7.7 17.3 20.0 6.3 4.7 4.3 8.1 6.0 PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40217428-40277487 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 25.6;skin 1: 28.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;NK-cells: 16.5;Suprabasal keratinocytes: 19.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 26.5;HaCaT: 32.2;hTCEpi: 19.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031124 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: AB_10601044" "unprognostic (1.85e-3)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (7.79e-3)" "unprognostic (7.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (1.34e-2)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (8.87e-3)" "unprognostic (1.72e-1)" "unprognostic (1.79e-1)" "unprognostic (7.37e-3)" "unprognostic (3.34e-2)" 0.2 8.2 11.6 0.4 15.9 0.9 2.1 8.5 16.6 4.5 0.0 1.3 1.5 0.9 1.0 25.6 4.3 1.1 8.3 17.6 3.0 4.7 0.3 2.5 0.9 1.4 1.1 0.6 8.0 8.0 12.1 7.6 1.9 4.4 1.1 0.8 6.1 3.8 4.5 28.2 1.5 0.3 1.8 0.9 3.9 17.7 3.0 0.5 7.5 1.3 1.9 3.5 9.4 5.4 3.9 0.0 0.2 0.0 0.0 0.0 6.0 0.0 0.2 0.7 0.7 26.5 2.9 0.1 3.6 0.0 1.3 32.2 4.5 6.9 0.3 0.2 1.0 0.0 3.0 0.2 0.0 0.1 0.3 0.0 19.4 0.3 4.5 0.2 0.0 5.5 1.8 0.3 0.0 4.5 0.0 0.5 0.5 3.9 2.9 0.2 0.2 2.9 1.5 8.4 7.3 2.0 2.6 10.9 0.3 1.7 1.7 10.3 0.0 0.3 0.6 0.0 0.3 0.1 0.3 0.1 0.7 0.6 0.2 1.2 0.1 1.2 2.3 0.1 0.8 0.6 0.1 1.9 0.3 0.1 0.1 0.4 0.5 0.9 0.1 0.1 0.0 0.6 11.6 15.9 8.5 16.6 17.6 3.0 1.4 1.1 1.9 1.8 3.0 5.4 0.0 0.0 4.2 0.7 0.3 9.8 9.6 4.8 8.6 3.5 2.8 2.9 0.0 4.3 5.4 5.5 0.0 52.7 2.1 0.3 13.7 4.4 8.6 3.3 0.4 0.3 4.9 0.0 8.9 4.3 3.0 0.7 0.5 5.1 0.0 0.7 0.0 0.0 4.1 0.0 7.3 1.1 2.0 0.6 0.9 5.8 1.8 0.3 1.8 1.0 0.0 1.3 16.5 0.5 0.3 2.5 1.0 1.9 0.1 5.2 0.2 0.2 3.9 0.2 0.0 0.3 0.4 1.9 3.3 13.9 19.0 9.0 1.0 0.8 2.0 11.3 PALLD "CGI-151, KIAA0992, SIH002" ENSG00000129116 "Palladin, cytoskeletal associated protein" Q8WX93 4 168497052-168928457 "Disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 527.9;Cardiomyocytes: 591.7;Peritubular cells: 399.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 304.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035905, CAB070159" Enhanced Supported "Plasma membrane,Actin filaments,Mitochondria,Cytosol" No No 27000 "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "Plasma membrane, Mitochondria, Cytosol" "CAB070159: AB_1726016, HPA035905: AB_2674854" "unprognostic (3.59e-2)" "unprognostic (3.99e-1)" "unprognostic (2.55e-2)" "unprognostic (5.03e-3)" "unprognostic (2.51e-1)" "unprognostic (7.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.40e-2)" "unprognostic (3.57e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (3.86e-1)" "unprognostic (8.54e-2)" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.28e-4)" 65.0 35.5 31.7 49.7 27.3 0.9 43.6 11.1 19.9 146.1 0.0 303.3 29.0 301.5 21.9 122.6 118.4 71.0 180.4 27.9 36.2 42.1 12.4 71.7 16.9 29.8 25.9 62.1 13.2 55.6 11.3 62.1 25.1 137.0 74.9 12.8 40.8 205.7 127.7 34.7 64.1 303.1 21.4 60.5 94.8 35.1 24.7 23.3 38.7 47.3 16.6 280.2 85.3 22.7 82.1 39.6 87.9 53.4 77.2 83.9 123.6 53.7 137.6 47.2 66.7 1.1 4.6 36.6 14.4 23.7 29.0 17.0 54.1 138.8 60.5 73.9 16.6 0.8 112.5 10.4 135.5 0.4 1.0 132.8 84.4 85.5 125.4 115.0 20.8 19.7 0.1 0.5 304.5 3.8 23.8 1.4 24.9 20.8 24.1 8.3 81.4 0.8 5.3 16.4 9.0 46.4 102.8 8.1 7.3 151.2 48.6 0.5 64.4 50.3 192.1 20.7 90.1 47.8 0.7 1.7 41.6 1.0 14.2 13.7 3.1 0.0 4.6 1.8 0.2 0.1 0.5 2.4 2.1 0.1 0.6 1.6 0.7 0.6 1.2 0.2 0.8 1.8 31.7 27.3 11.1 19.9 27.9 36.2 29.8 25.9 25.1 21.4 24.7 22.7 22.7 32.1 9.4 167.8 1.5 93.6 527.9 56.8 76.8 6.0 46.0 107.9 591.7 20.0 58.7 44.1 18.8 52.1 8.1 20.9 1.9 27.6 133.1 52.8 181.2 27.7 44.8 0.8 27.8 51.3 115.6 130.5 59.7 51.0 52.6 21.0 47.8 11.2 24.5 26.9 108.4 30.7 18.3 28.9 23.8 146.4 130.1 36.7 23.2 16.9 52.9 55.1 17.5 182.4 6.5 83.0 18.6 399.4 2.6 167.6 9.8 23.4 85.2 4.0 177.5 115.4 227.8 81.0 7.6 34.1 49.3 22.3 9.2 13.4 29.3 113.0 PAQR7 "MPRA, mSR" ENSG00000182749 "Progestin and adipoQ receptor family member 7" Q86WK9 1 25861484-25875708 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1939.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 75.5;HaCaT: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046936 Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA046936: AB_2679869" "unprognostic (1.12e-1)" "unprognostic (2.08e-2)" "unprognostic (8.03e-2)" "unprognostic (4.54e-3)" "unprognostic (1.32e-1)" "unprognostic (3.41e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.47e-1)" "unprognostic (4.59e-3)" "unprognostic (7.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.05e-5)" "unprognostic (1.60e-2)" "unprognostic (2.98e-2)" "unprognostic (1.15e-2)" "unprognostic (1.54e-2)" 5.5 23.9 8.5 4.4 8.4 5.1 5.2 7.5 8.6 11.9 10.0 6.4 20.9 11.1 28.2 17.7 20.0 7.8 3.3 7.9 10.1 35.3 7.4 5.6 4.3 9.6 10.2 35.3 6.6 13.7 6.7 21.4 9.4 7.9 2.9 1.5 5.3 24.3 3.0 31.4 18.9 9.5 9.2 10.2 8.1 46.2 10.6 3.5 5.1 1.9 4.9 13.6 13.5 9.4 30.7 6.0 5.8 18.9 7.1 14.8 20.4 19.9 17.5 19.2 17.0 9.8 75.5 0.3 13.6 19.2 6.3 62.6 3.2 33.0 11.4 12.1 3.4 25.6 8.4 12.1 12.0 0.4 3.1 14.9 43.3 13.7 10.2 16.9 7.5 2.8 2.8 2.1 14.4 7.0 0.2 1.9 9.3 3.1 10.3 2.1 0.6 3.8 39.3 22.9 3.1 11.5 32.1 40.7 14.8 7.9 11.6 4.6 8.1 3.1 9.7 10.2 5.4 0.4 0.4 1.3 14.5 0.7 6.6 5.4 7.3 15.7 1.4 13.9 1.4 4.0 0.8 1.0 7.6 1.7 1.3 1.9 3.7 3.4 17.5 0.8 0.2 1.4 8.5 8.4 7.5 8.6 7.9 10.1 9.6 10.2 9.4 9.2 10.6 9.4 4.9 0.0 3.1 11.4 2.2 18.1 4.3 4.6 4.6 2.1 9.4 9.5 1.9 17.2 5.1 77.3 0.0 52.8 1.3 0.7 21.5 5.6 350.9 23.4 11.5 5.9 4.8 0.0 11.9 13.9 12.3 7.8 0.5 9.0 7.0 4.6 10.4 5.5 11.0 3.3 11.2 2.2 0.0 10.3 14.9 1939.3 19.9 7.8 21.4 7.5 7.6 1.6 0.0 8.5 4.0 6.4 3.0 15.1 0.7 3.1 27.9 70.2 8.6 0.6 13.1 4.3 4.7 11.6 10.0 4.7 13.1 35.7 1.6 5.8 3.7 3.1 PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9;Distal enterocytes: 398.3;Intestinal goblet cells: 109.7;Paneth cells: 132.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 44.6;Karpas-707: 44.9;U-266/70: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" 45.1 51.8 4.1 27.7 5.4 0.4 29.3 0.0 19.3 43.3 2.1 91.3 7.0 34.7 14.0 13.5 23.3 28.6 103.6 10.4 26.0 55.9 1.3 33.7 18.2 1.3 3.9 19.6 34.1 73.1 41.0 40.7 21.2 83.8 113.4 6.0 39.4 64.5 21.0 11.1 15.7 48.2 0.0 15.3 13.4 12.0 4.1 17.3 123.7 18.1 20.9 44.9 25.0 0.0 1.1 1.9 1.7 0.0 44.6 0.3 0.2 0.0 0.2 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.1 0.1 15.1 0.0 0.0 0.2 3.3 0.0 0.0 0.0 7.4 0.0 1.3 1.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 44.9 0.8 0.5 5.2 0.2 4.3 0.0 2.7 0.0 4.1 11.8 0.2 9.5 2.8 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.0 2.7 2.9 0.3 4.2 49.8 5.1 12.9 4.7 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.0 8.1 0.0 0.0 4.0 5.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 4.1 5.4 0.0 19.3 10.4 26.0 1.3 3.9 21.2 0.0 4.1 0.0 44.8 16.0 84.1 2.9 11.6 3.2 27.2 6.5 4.0 7.0 4.0 3.4 181.9 31.5 10.4 0.0 0.0 0.3 0.1 398.3 3.9 0.5 10.1 3.0 73.5 6.4 19.9 2.7 51.3 49.2 0.7 13.2 2.0 2.8 1.3 61.9 2.9 0.0 1.5 0.0 77.8 109.7 14.2 0.3 34.7 28.6 36.7 4.9 8.8 1.0 0.7 0.1 0.0 6.0 3.6 23.5 132.1 74.4 42.9 32.6 2.5 27.7 7.2 1.7 46.0 5.4 61.5 1.6 3.2 0.3 1.8 0.8 1.9 14.9 81.6 9.1 PARS2 DKFZp727A071 ENSG00000162396 "Prolyl-tRNA synthetase 2, mitochondrial" Q7L3T8 1 54756898-54764523 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 9.8;Early spermatids: 11.0;Spermatocytes: 10.5;Spermatogonia: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028308, HPA028314, HPA028518" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" No No "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center, Mitochondria" "HPA028308: AB_2672553, HPA028314: AB_10603981, HPA028518: AB_2672653" "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "prognostic favorable (1.26e-5)" "unprognostic (1.93e-2)" "unprognostic (1.19e-2)" "unprognostic (1.79e-3)" "prognostic unfavorable (2.34e-4)" "unprognostic (6.48e-2)" "unprognostic (2.72e-1)" "unprognostic (1.14e-1)" "unprognostic (9.42e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.24e-6)" "unprognostic (2.72e-2)" "unprognostic (9.77e-2)" "unprognostic (1.73e-2)" "unprognostic (9.64e-2)" 1.3 2.9 2.5 1.9 3.0 0.2 2.7 2.8 3.1 2.7 3.0 4.0 2.7 2.5 3.2 2.7 4.4 1.6 3.0 2.6 2.6 4.2 3.4 1.4 2.0 2.5 2.7 4.8 2.3 4.7 2.1 2.5 2.7 2.3 3.6 2.0 3.3 2.8 4.4 2.9 2.1 2.0 2.7 1.8 2.5 4.8 2.7 2.6 2.9 5.5 2.4 2.1 2.0 3.0 4.4 7.2 4.6 6.0 5.5 4.6 10.3 3.7 4.5 6.4 4.6 8.3 2.8 7.7 5.6 3.3 9.3 6.9 8.3 5.8 4.7 5.0 7.5 7.4 4.0 6.2 8.5 4.3 2.5 5.0 8.8 8.3 7.4 5.5 4.8 8.4 13.2 1.0 4.9 4.6 6.1 5.7 10.6 8.3 9.1 4.6 9.0 9.0 5.4 3.2 4.7 4.8 5.3 6.9 9.7 8.7 3.9 5.5 2.6 4.8 4.9 6.8 4.7 7.3 6.6 3.0 3.6 5.1 2.8 1.2 5.3 4.5 4.8 7.7 5.9 4.9 5.3 5.3 7.3 5.5 7.8 5.3 0.5 7.4 10.7 5.9 8.2 5.0 2.5 3.0 2.8 3.1 2.6 2.6 2.5 2.7 2.7 2.7 2.7 3.0 0.6 0.0 1.1 0.3 1.0 0.6 0.9 2.0 1.8 2.6 1.3 1.9 1.5 2.8 1.8 0.0 0.0 7.0 0.2 2.4 9.8 4.5 11.0 1.1 1.4 0.8 0.0 0.0 0.9 2.8 3.9 1.3 1.5 0.6 0.0 2.9 0.0 2.3 3.1 5.0 1.1 2.8 0.0 1.2 0.3 6.8 3.7 0.8 0.0 2.8 1.1 3.2 0.0 0.5 1.6 1.9 1.5 3.0 0.3 1.8 1.5 6.5 1.0 1.9 0.0 1.3 1.1 10.5 11.5 2.0 1.0 3.3 0.7 5.1 3.5 0.8 PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 29 "B-cells: 91.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 9 "Daudi: 66.6;REH: 194.1;U-698: 87.1" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394, HPA068498" Enhanced Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center, Vesicles, Cytosol" "CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" 0.3 0.1 0.4 14.9 0.3 9.4 0.1 0.5 0.5 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.8 0.2 0.3 0.6 0.1 0.2 0.3 39.7 1.1 6.5 0.0 0.0 0.0 0.2 0.1 4.1 0.3 0.8 0.5 1.0 0.0 3.1 0.0 6.6 0.0 0.8 18.7 1.6 0.6 1.9 2.8 0.2 0.0 36.2 1.1 0.0 0.3 0.1 0.3 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 66.6 0.1 0.0 0.1 0.2 0.1 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 0.1 0.3 1.9 0.3 0.4 194.1 0.4 0.3 0.0 0.0 13.2 2.9 0.1 0.7 0.0 0.0 0.0 7.5 0.2 0.0 0.2 0.1 0.0 0.2 0.1 87.1 0.0 1.5 0.1 0.7 0.0 0.1 0.0 0.1 0.1 39.0 0.0 0.0 0.1 26.0 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.7 0.4 0.3 0.5 0.5 0.3 0.6 1.1 6.5 4.1 0.8 1.9 0.3 0.0 0.0 0.0 0.7 91.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.3 0.0 3.1 0.0 0.9 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.0 0.1 0.0 2.7 0.4 0.0 0.1 0.0 0.1 0.0 0.8 0.1 0.6 0.2 0.2 0.0 0.0 2.0 0.0 0.0 0.3 PBX3 ENSG00000167081 "PBX homeobox 3" P40426 9 125747345-125967377 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 153.1" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8;Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 192.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 39.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 13.9" "Lineage enriched" "Detected in all" 4 "dendritic cells: 13.9" "Cell line enhanced" "Detected in many" "THP-1: 90.1" "Region enhanced" "Detected in all" "olfactory bulb: 167.4" "Group enriched" "Detected in all" 5 "basal ganglia: 46.3;olfactory bulb: 161.9" HPA003881 Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA003881: AB_1855020" "unprognostic (1.97e-2)" "unprognostic (3.78e-2)" "unprognostic (1.15e-1)" "unprognostic (1.93e-2)" "unprognostic (1.27e-1)" "unprognostic (2.35e-1)" "unprognostic (2.20e-1)" "unprognostic (3.38e-2)" "unprognostic (2.83e-1)" "unprognostic (2.88e-1)" "unprognostic (2.42e-3)" "unprognostic (7.02e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-2)" "unprognostic (1.63e-1)" "unprognostic (8.03e-2)" "unprognostic (6.29e-2)" 10.9 56.0 10.4 12.9 14.6 6.9 10.0 17.4 13.2 27.2 7.0 47.9 6.8 9.8 20.0 11.8 14.2 22.5 38.0 7.2 15.0 7.1 18.1 13.0 8.0 19.7 21.0 58.2 18.8 153.1 12.6 6.7 19.4 30.9 13.7 28.0 11.8 28.0 8.5 19.4 14.3 22.6 18.8 12.8 21.5 8.2 15.3 16.7 35.1 5.7 6.9 20.7 21.9 21.7 11.6 11.0 50.0 43.1 13.1 19.1 8.5 29.9 16.8 19.2 14.5 14.3 21.1 11.3 3.6 22.1 20.8 8.5 28.3 12.3 38.3 12.4 20.5 9.7 7.9 5.8 17.2 9.6 15.5 9.5 13.7 14.5 10.0 45.3 23.1 7.2 0.4 10.3 43.5 5.9 10.0 4.9 35.8 14.2 7.4 18.9 73.3 1.5 15.6 6.4 25.9 45.1 20.2 3.8 9.4 18.8 15.7 90.1 26.6 40.0 10.2 23.8 57.1 7.2 12.8 11.5 19.7 15.2 20.6 2.3 1.7 2.2 0.8 1.4 0.9 1.0 0.9 0.7 1.9 1.5 1.7 0.7 1.4 3.2 1.3 13.9 0.8 1.0 10.4 14.6 17.4 13.2 7.2 15.0 19.7 21.0 19.4 18.8 15.3 21.7 7.3 9.6 16.7 17.9 10.0 22.7 10.3 3.0 6.8 7.5 11.5 8.3 60.3 2.8 8.6 12.9 37.5 0.6 20.7 1.3 7.9 13.5 15.2 1.1 14.0 11.9 11.5 6.3 44.3 2.5 0.9 23.4 5.6 1.5 16.5 9.4 9.7 12.6 15.3 42.1 19.3 5.7 6.1 29.0 23.7 11.4 19.9 22.9 7.2 91.8 13.6 11.5 6.2 136.2 192.2 3.1 12.1 11.3 3.8 13.0 0.9 2.8 8.5 43.1 0.0 5.3 13.0 33.7 16.0 10.4 26.3 0.4 10.5 8.7 3.4 8.7 PCCB ENSG00000114054 "Propionyl-CoA carboxylase subunit beta" P05166 3 136250340-136337896 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 202.1" "Cell type enhanced" "Detected in all" "Early spermatids: 316.7;Late spermatids: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036939, HPA036940" Enhanced "Intracellular and membrane" NA NA 120000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "HPA036939: AB_10671366, HPA036940: AB_10669779" "unprognostic (2.74e-1)" "unprognostic (7.88e-3)" "unprognostic (3.99e-2)" "unprognostic (2.89e-2)" "unprognostic (2.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.05e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-2)" "unprognostic (2.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.47e-7)" "unprognostic (2.43e-2)" "unprognostic (2.64e-1)" "unprognostic (3.50e-1)" "unprognostic (4.13e-1)" 34.4 75.1 23.3 15.2 33.6 37.9 27.5 31.4 29.3 17.5 35.5 43.6 38.1 13.8 13.9 26.3 19.2 17.0 94.6 23.6 28.5 88.9 202.1 14.8 16.2 31.1 29.4 12.1 32.0 57.0 15.6 19.6 30.4 23.7 41.9 17.2 23.6 21.7 83.8 15.1 27.5 22.6 27.1 12.7 26.1 38.8 29.8 21.1 37.9 91.4 20.7 20.5 11.4 47.8 64.8 45.8 42.4 64.4 30.2 34.5 75.4 33.0 35.5 49.1 69.6 67.9 44.7 80.3 89.4 46.6 44.0 35.1 50.3 44.0 69.4 47.8 43.0 140.8 49.5 101.4 66.4 107.3 60.2 40.8 41.4 31.0 69.4 30.5 56.1 131.6 104.5 41.0 38.0 123.1 109.3 63.1 36.0 96.8 40.9 29.3 34.6 116.6 89.9 69.4 84.0 62.9 84.4 48.9 77.5 35.2 98.3 62.9 42.0 24.5 26.0 69.2 29.6 78.3 70.0 66.9 34.9 41.7 29.9 7.3 29.5 7.5 22.6 30.8 25.4 21.7 14.7 23.2 44.6 19.8 15.1 18.7 2.7 25.9 28.7 38.5 14.8 22.6 23.3 33.6 31.4 29.3 23.6 28.5 31.1 29.4 30.4 27.1 29.8 47.8 5.6 9.6 14.0 16.0 9.2 4.1 9.4 37.9 3.4 16.0 12.5 5.3 51.1 8.6 28.4 20.2 10.4 57.1 8.0 15.1 39.2 24.6 316.7 14.1 9.5 8.1 9.1 53.2 16.5 14.0 27.1 13.6 14.8 14.1 29.2 18.1 9.3 76.3 35.1 11.8 22.7 15.1 24.4 11.7 5.2 159.0 13.7 11.4 19.6 16.9 16.5 11.8 10.3 22.1 50.9 14.4 16.7 10.9 22.6 10.4 19.2 97.3 23.6 13.2 13.1 13.6 13.1 11.3 29.0 16.2 3.3 50.9 9.9 52.8 25.1 12.2 PCDH11X "PCDH-X, PCDH11, PCDHX, PPP1R119" ENSG00000102290 "Protocadherin 11 X-linked" Q9BZA7 X 91779261-92623230 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 10.7;ovary: 7.4" "Group enriched" "Detected in many" 6 "Excitatory neurons: 120.4;Inhibitory neurons: 349.7;Oligodendrocyte precursor cells: 173.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.5;AN3-CA: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077495 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA077495: " "unprognostic (4.22e-3)" "unprognostic (1.16e-1)" "unprognostic (1.39e-4)" "unprognostic (1.18e-1)" "unprognostic (8.20e-3)" "unprognostic (6.32e-2)" "unprognostic (9.10e-2)" "unprognostic (6.19e-2)" "unprognostic (4.58e-1)" "unprognostic (1.58e-1)" "unprognostic (2.45e-2)" "unprognostic (3.86e-1)" 0.0 0.2 10.7 0.2 7.7 0.0 0.2 0.0 3.7 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 6.2 0.0 0.0 0.0 0.2 1.6 4.8 7.4 0.0 1.0 0.2 0.8 2.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 7.8 0.0 0.1 0.2 0.2 0.0 0.0 1.2 0.0 0.0 1.5 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 7.7 0.0 3.7 2.4 6.2 1.6 4.8 2.0 0.0 7.8 1.2 0.5 9.6 7.4 2.3 0.2 1.5 0.5 0.2 1.2 4.2 1.0 1.8 0.7 0.0 3.2 0.0 0.0 20.8 0.1 0.1 0.0 0.0 0.6 0.2 0.1 2.1 0.0 0.0 120.4 0.0 0.3 1.0 0.0 0.2 1.3 0.1 4.6 0.3 1.0 33.7 349.7 0.0 0.0 0.0 2.0 0.6 9.6 1.0 10.6 12.2 0.0 0.2 0.0 173.9 5.3 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.8 1.4 6.6 0.6 0.8 0.3 1.0 0.1 0.9 15.7 0.6 0.1 0.1 0.4 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;lymphoid tissue: 25.1" "Group enriched" "Detected in many" 4 "Adipocytes: 57.6;Astrocytes: 77.1;Early spermatids: 60.7;Endothelial cells: 126.7;Excitatory neurons: 125.2;Hepatic stellate cells: 79.6;Inhibitory neurons: 67.9;Oligodendrocyte precursor cells: 193.0;Oligodendrocytes: 101.1;Spermatocytes: 68.3" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;HEK 293: 9.3;U-87 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" 1.6 1.8 15.8 1.8 20.6 0.0 0.8 7.9 13.9 2.2 0.1 1.2 0.8 2.1 0.8 0.6 2.0 3.2 2.2 11.7 25.5 1.9 1.0 14.0 0.6 9.3 15.8 0.5 6.0 1.6 0.9 4.4 11.4 1.0 0.8 1.0 0.7 0.7 1.7 0.3 0.8 2.1 7.6 25.1 1.5 8.8 27.9 0.2 2.9 1.3 0.5 2.7 0.8 10.5 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 9.3 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 1.2 0.0 1.0 0.0 0.0 0.0 5.3 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 20.6 7.9 13.9 11.7 25.5 9.3 15.8 11.4 7.6 27.9 10.5 57.6 0.0 4.3 77.1 0.1 2.7 0.1 0.0 1.2 7.1 0.4 0.6 6.0 1.5 8.6 1.8 0.0 0.2 0.5 0.1 0.0 11.1 60.7 2.6 2.0 126.7 0.0 0.0 125.2 8.3 0.1 11.7 0.0 19.8 0.0 20.5 79.6 0.3 0.6 0.0 67.9 0.0 0.0 1.9 2.5 19.0 1.8 0.5 10.6 12.2 1.6 2.3 0.0 193.0 101.1 1.3 0.0 1.2 1.2 0.3 0.0 0.0 5.1 0.0 6.6 1.9 10.7 68.3 10.6 0.4 1.0 0.0 1.1 1.6 0.0 0.4 PCLAF "KIAA0101, NS5ATP9, OEATC-1, p15(PAF), PAF15" ENSG00000166803 "PCNA clamp associated factor" Q15004 15 64364304-64387687 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 128.6;lymphoid tissue: 73.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 82.2;Extravillous trophoblasts: 160.2;Granulosa cells: 48.8;Hofbauer cells: 110.2;Syncytiotrophoblasts: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 4 "T-reg: 23.6" "Lineage enriched" "Detected in many" 4 "T-cells: 23.6" "Low cell line specificity" "Detected in all" HPA047929 Supported Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA047929: AB_2680215" "unprognostic (5.34e-2)" "unprognostic (1.36e-3)" "unprognostic (9.39e-2)" "unprognostic (1.28e-1)" "unprognostic (4.16e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.26e-5)" "unprognostic (4.38e-3)" "unprognostic (1.91e-3)" "unprognostic (7.26e-2)" "unprognostic (2.56e-3)" "unprognostic (9.65e-2)" "prognostic unfavorable (9.77e-15)" "unprognostic (5.59e-2)" "unprognostic (2.05e-1)" "unprognostic (8.65e-2)" "unprognostic (3.22e-1)" 2.1 1.4 0.9 22.9 1.0 128.6 3.9 1.4 1.1 1.7 0.8 19.0 14.7 4.5 1.2 15.2 1.3 2.5 0.4 0.9 0.6 1.2 3.6 2.5 49.5 1.0 0.8 0.4 1.9 0.8 0.5 8.7 0.9 2.0 22.6 0.3 2.3 0.3 0.4 6.7 15.8 5.0 0.5 7.4 8.1 1.1 1.0 73.8 2.2 0.1 47.1 7.9 4.9 1.9 212.6 165.8 154.4 140.8 15.9 60.9 134.4 146.2 84.8 185.4 276.4 198.4 202.1 343.7 46.4 57.4 64.8 153.6 340.7 83.1 235.3 192.5 124.8 352.5 202.5 209.8 1.5 285.3 153.8 20.0 7.9 156.4 31.9 52.3 168.9 175.9 201.3 104.4 248.1 187.8 268.0 605.5 73.9 179.9 73.4 416.6 353.8 247.1 115.9 200.2 19.1 86.7 112.8 105.2 69.3 78.9 153.8 365.3 36.3 158.4 308.6 177.8 386.7 65.5 223.4 229.0 67.7 512.9 108.5 2.4 0.3 0.9 1.4 0.2 0.2 2.0 4.4 4.2 2.8 0.6 0.5 1.0 2.7 5.7 0.4 0.3 23.6 2.3 0.9 1.0 1.4 1.1 0.9 0.6 1.0 0.8 0.9 0.5 1.0 1.9 0.5 9.6 11.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 27.5 25.5 0.0 0.0 5.0 1.8 0.0 82.2 8.3 0.0 1.9 6.5 0.0 18.6 10.4 8.5 0.0 0.0 0.0 3.0 160.2 25.4 0.0 13.8 3.8 48.8 0.0 0.0 110.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 4.3 0.0 0.0 3.0 3.6 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.0 42.1 5.8 7.6 0.0 0.0 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 28.5;brain: 30.2;retina: 35.8;thyroid gland: 56.9" "Cell type enhanced" "Detected in many" "Early spermatids: 87.3;Excitatory neurons: 322.8;Horizontal cells: 132.9;Inhibitory neurons: 148.8;Melanocytes: 209.9;Muller glia cells: 452.7" "Cancer enriched" "Detected in many" 4 "thyroid cancer: 65.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 60.0;SCLC-21H: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" NA NA 18000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA049627: AB_2680835" "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 0.7 28.5 8.6 0.8 14.9 0.5 0.4 0.1 30.2 1.6 0.0 6.9 4.8 0.2 0.3 1.1 1.0 0.5 4.7 15.8 11.1 0.2 0.2 2.5 0.0 2.2 1.3 9.0 19.8 0.8 2.0 0.6 2.6 1.4 1.7 35.8 1.7 1.2 0.1 14.1 2.1 0.4 1.4 0.1 8.1 4.8 13.2 0.0 56.9 0.1 0.1 3.0 2.4 11.9 0.0 0.0 60.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 14.9 0.1 30.2 15.8 11.1 2.2 1.3 2.6 1.4 13.2 11.9 0.1 0.0 7.3 7.8 0.0 8.2 0.0 0.0 1.2 28.1 0.0 0.0 1.2 0.0 0.6 0.0 6.2 0.0 0.0 0.0 0.0 0.0 87.3 0.0 0.0 1.3 0.0 0.0 322.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 132.9 148.8 0.6 0.0 0.0 1.3 6.3 2.8 0.2 209.9 8.4 0.0 452.7 0.0 44.7 6.4 2.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.5 1.2 1.0 0.3 0.2 1.4 0.0 0.1 0.6 0.0 0.1 PCYT1A "CT, CTPCT, PCYT1" ENSG00000161217 "Phosphate cytidylyltransferase 1, choline, alpha" P49585 3 196214222-196287957 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Cone-rod dystrophy, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035428 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA035428: AB_10602045" "unprognostic (8.58e-3)" "unprognostic (2.63e-1)" "unprognostic (8.45e-2)" "unprognostic (8.61e-3)" "unprognostic (2.87e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (8.52e-2)" "unprognostic (5.99e-2)" "unprognostic (1.65e-2)" "unprognostic (6.72e-3)" "unprognostic (1.74e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (7.16e-3)" "unprognostic (2.41e-2)" 31.4 24.4 15.2 30.0 16.0 45.3 21.0 16.6 15.8 16.7 17.8 25.7 60.3 19.1 13.9 31.0 15.6 20.7 46.4 15.5 21.1 18.3 20.7 22.5 22.9 18.8 18.0 15.8 16.8 22.7 12.9 20.1 18.5 16.6 22.9 14.4 19.3 18.6 73.8 43.0 49.1 23.0 17.5 25.9 24.2 22.4 18.1 18.1 17.2 42.1 26.8 21.0 19.8 17.1 92.6 36.6 25.8 37.2 52.2 53.9 37.0 68.2 47.1 59.2 51.8 92.3 32.8 23.9 215.2 78.1 60.2 71.4 40.5 52.1 50.4 42.1 28.6 68.6 40.6 39.5 45.2 34.3 56.7 47.4 40.0 55.9 39.6 35.4 63.0 21.0 38.3 53.3 58.1 79.6 19.9 17.3 21.4 55.7 53.0 34.5 31.0 37.5 35.7 53.6 25.4 18.3 44.5 79.5 44.2 32.8 114.1 37.2 88.5 45.5 25.2 61.8 92.7 45.8 101.1 44.1 69.6 43.8 56.9 9.6 9.2 10.4 8.8 9.3 7.5 7.2 6.5 9.7 9.1 6.3 4.2 6.3 21.0 9.4 11.0 5.9 14.9 5.2 15.2 16.0 16.6 15.8 15.5 21.1 18.8 18.0 18.5 17.5 18.1 17.1 24.7 16.0 25.7 15.3 19.9 14.5 9.4 19.7 14.2 15.9 14.1 9.4 70.1 20.0 17.5 14.7 25.0 11.9 27.3 36.4 13.7 24.8 76.3 17.8 22.9 23.2 22.1 12.2 20.4 22.9 17.7 17.0 23.4 15.6 20.8 16.1 26.7 35.6 37.4 8.4 22.7 24.2 6.1 34.6 27.1 67.6 19.9 33.9 19.6 20.6 39.4 13.1 39.1 16.1 17.6 24.6 21.1 28.2 27.2 12.0 67.2 23.2 33.9 12.8 26.3 15.0 19.0 46.0 13.2 30.0 21.5 18.6 25.6 25.5 23.8 12.2 PDCD1 "CD279, hSLE1, PD-1, PD1, SLEB2" ENSG00000188389 "Programmed cell death 1" Q15116 2 241849884-241858894 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Immunity" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.7;lymphoid tissue: 16.1" "Group enriched" "Detected in some" 4 "Plasma cells: 9.5;T-cells: 34.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.4" "Group enriched" "Detected in many" 5 "gdT-cell: 4.4;MAIT T-cell: 4.8;memory CD4 T-cell: 8.7;memory CD8 T-cell: 12.4;T-reg: 4.3" "Lineage enriched" "Detected in single" 55 "T-cells: 12.4" "Cell line enhanced" "Detected in some" "JURKAT: 1.5;MOLT-4: 2.4;RPMI-8226: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035981, CAB038418, CAB076386" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB038418: AB_1160824, CAB076386: AB_881954, HPA035981: AB_10669664" "unprognostic (2.90e-3)" "unprognostic (4.50e-3)" "unprognostic (7.78e-2)" "prognostic favorable (9.44e-5)" "unprognostic (7.18e-3)" "unprognostic (1.31e-3)" "unprognostic (3.83e-2)" "unprognostic (7.33e-2)" "unprognostic (5.82e-3)" "unprognostic (3.75e-2)" "unprognostic (6.57e-2)" "unprognostic (3.94e-1)" "prognostic unfavorable (3.48e-7)" "unprognostic (1.20e-2)" "unprognostic (3.10e-1)" "unprognostic (5.35e-2)" "unprognostic (5.06e-3)" 1.2 0.3 0.0 3.2 0.2 0.9 0.4 0.0 0.1 0.6 0.2 0.8 0.3 0.4 0.0 0.8 0.6 0.3 6.7 0.1 0.1 0.7 0.4 1.8 16.1 0.1 1.4 0.2 0.3 0.0 1.5 0.0 0.2 0.7 0.1 0.0 1.0 0.2 0.1 0.3 3.8 0.2 0.1 7.0 1.8 0.3 0.4 3.1 1.5 0.0 4.0 1.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.3 2.4 0.0 0.0 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 4.8 0.2 8.7 12.4 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 4.3 2.1 0.0 0.2 0.0 0.1 0.1 0.1 0.1 1.4 0.2 0.1 0.4 0.2 0.4 0.0 0.6 0.0 3.6 0.4 0.3 0.0 0.0 0.0 0.3 0.5 0.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.6 0.0 34.7 0.0 0.0 0.1 PDCL3 VIAF1 ENSG00000115539 "Phosducin like 3" Q9H2J4 2 100562993-100576739 "Predicted intracellular proteins" "Angiogenesis, Apoptosis" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018469, HPA027094" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA018469: AB_1855116, HPA027094: AB_10601387" "unprognostic (1.34e-1)" "unprognostic (8.30e-2)" "unprognostic (2.20e-1)" "unprognostic (3.32e-2)" "unprognostic (5.07e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.07e-5)" "unprognostic (1.44e-1)" "unprognostic (5.46e-2)" "unprognostic (1.66e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (8.22e-2)" "prognostic favorable (4.23e-4)" 20.8 22.0 19.1 27.1 21.6 22.9 23.0 21.6 24.3 18.9 16.6 27.3 17.0 24.1 37.2 36.8 22.5 21.3 30.6 18.4 21.3 28.4 18.5 18.4 25.3 21.8 24.7 21.1 11.4 23.4 10.5 23.4 21.7 27.0 28.9 21.1 16.9 23.2 58.8 36.8 17.3 38.6 20.8 17.0 17.6 22.8 22.1 22.4 21.4 34.3 34.0 33.1 17.5 22.2 41.8 58.7 59.9 52.2 19.3 27.4 67.5 51.3 32.5 92.9 58.1 74.2 25.5 68.6 74.0 62.3 122.3 34.2 76.0 50.2 74.0 110.6 65.8 72.0 31.8 89.7 50.8 77.3 73.2 29.8 92.0 82.0 52.3 24.2 58.9 52.8 61.1 43.8 70.7 74.6 75.8 117.7 77.9 45.6 86.6 72.5 63.2 48.0 58.2 98.7 55.9 49.6 41.0 54.7 59.0 48.6 42.3 53.0 45.8 56.4 60.1 44.8 72.2 26.4 54.1 68.3 34.4 90.5 45.7 82.3 64.8 80.2 63.1 124.4 72.8 92.5 95.0 70.4 114.9 78.1 97.7 75.4 7.0 93.9 161.7 64.0 113.6 87.3 19.1 21.6 21.6 24.3 18.4 21.3 21.8 24.7 21.7 20.8 22.1 22.2 37.4 19.2 25.2 1.6 39.5 65.6 36.6 79.2 52.9 13.0 24.8 36.2 40.9 18.6 46.1 14.7 6.2 70.8 61.5 16.0 60.7 50.6 37.0 38.9 26.6 30.2 19.8 21.7 2.3 39.1 51.2 22.6 19.4 34.6 92.9 25.4 12.5 17.0 59.7 11.8 2.0 24.0 89.5 17.8 80.7 14.3 14.6 54.4 35.6 3.7 104.3 19.7 40.2 2.0 4.5 31.8 18.6 33.4 27.7 33.2 19.7 77.9 28.1 16.5 52.6 23.8 54.1 5.5 66.9 63.2 57.5 52.4 91.8 24.5 31.3 32.4 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Astrocytes: 98.2;Bipolar cells: 38.4;Cardiomyocytes: 131.3;Horizontal cells: 52.2;Inhibitory neurons: 78.8;Smooth muscle cells: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.6;HEL: 15.3;HeLa: 42.5;HUVEC TERT2: 7.4;SH-SY5Y: 17.9;U-138 MG: 11.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.8" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 6.5 1.0 1.6 3.1 1.3 0.2 3.8 3.1 1.3 6.7 1.8 15.0 1.9 4.2 1.4 2.2 4.1 4.7 43.4 1.3 1.5 3.3 1.3 3.9 1.0 1.9 2.3 3.4 6.2 0.6 2.1 11.3 1.2 5.4 7.6 5.7 2.7 3.5 2.2 1.3 9.6 5.2 1.6 2.2 5.1 0.4 2.5 0.6 2.8 1.8 0.5 2.5 3.1 1.4 0.0 0.2 8.6 0.0 1.9 1.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.3 42.5 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 1.1 0.0 0.0 0.0 2.7 0.0 0.1 17.9 0.0 0.0 0.1 3.3 0.0 0.0 0.3 11.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.3 1.3 1.5 1.9 2.3 1.2 1.6 2.5 1.4 2.7 0.0 0.0 98.2 0.0 0.3 0.2 0.0 0.6 38.4 0.2 0.3 131.3 4.3 0.6 0.0 0.0 0.0 0.0 28.4 0.0 5.8 0.7 0.5 1.6 3.9 4.2 0.0 4.1 0.5 0.0 11.3 0.0 1.4 17.1 0.0 2.2 0.0 0.7 52.2 78.8 7.0 0.0 0.0 0.7 0.6 1.5 3.1 1.8 27.2 0.5 4.4 0.0 27.6 3.9 0.4 26.9 0.7 0.0 0.5 33.4 3.1 0.0 2.8 6.6 3.6 49.9 0.3 0.9 0.9 0.3 0.0 0.6 0.5 16.4 0.2 PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469630 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 190.8;Late spermatids: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 36.5;NB-4: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB017632: AB_1127109, HPA043310: AB_2678419, HPA076091: AB_2686775" "unprognostic (1.29e-2)" "unprognostic (3.98e-2)" "unprognostic (8.91e-2)" "unprognostic (1.82e-1)" "unprognostic (7.00e-2)" "unprognostic (6.84e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-2)" "unprognostic (6.90e-2)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (1.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.15e-1)" 13.7 5.6 10.9 5.9 12.5 5.4 9.7 3.0 32.3 12.4 0.0 11.0 2.7 9.8 1.4 4.1 7.5 6.6 12.5 11.8 7.9 7.0 2.5 13.0 3.2 21.9 7.1 1.5 12.7 22.2 3.9 6.5 20.8 8.4 4.0 5.3 9.8 4.8 37.9 5.4 6.5 6.2 1.1 8.2 12.9 24.5 13.0 1.6 11.0 16.9 2.6 8.2 8.2 15.7 0.1 2.5 0.5 6.7 18.7 11.1 3.7 5.6 11.1 0.7 1.9 6.0 5.4 2.6 16.1 14.6 0.4 0.6 3.9 0.7 0.4 6.7 5.5 23.7 8.1 6.7 12.3 3.9 36.5 8.3 0.8 6.2 0.0 0.7 5.3 2.1 18.9 5.5 4.0 1.7 2.3 43.3 2.9 6.7 4.7 15.6 3.7 20.3 0.9 1.4 4.2 1.5 0.4 0.2 6.2 1.0 0.8 7.8 11.2 8.3 10.5 5.7 3.7 10.9 0.9 12.4 3.5 0.3 6.7 4.1 1.7 3.4 0.8 2.5 0.4 0.1 0.3 1.1 2.0 0.0 0.0 0.4 0.1 3.0 2.7 0.1 0.7 1.1 10.9 12.5 3.0 32.3 11.8 7.9 21.9 7.1 20.8 1.1 13.0 15.7 9.4 3.2 11.6 6.2 10.8 10.1 2.6 2.5 1.8 25.6 6.4 4.3 7.7 8.6 5.5 9.2 0.0 0.5 58.9 7.1 0.0 3.1 48.9 2.1 20.7 8.6 0.0 1.7 39.4 12.9 4.8 12.1 7.1 3.6 31.8 0.3 10.4 0.9 10.2 55.5 43.5 5.1 6.1 22.1 190.8 197.0 17.4 53.9 14.2 12.2 15.4 1.2 22.6 12.5 1.5 12.3 3.8 18.0 27.0 3.0 0.1 0.2 6.9 3.6 6.6 9.0 10.2 8.6 8.5 0.5 8.1 0.4 37.0 1.0 6.8 1.3 PDHA1 PDHA ENSG00000131828 "Pyruvate dehydrogenase E1 subunit alpha 1" P08559 X 19343893-19361718 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 508.8;tongue: 770.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 479.9;Distal tubular cells: 354.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria "Intracellular and membrane" NA NA 100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931" "unprognostic (5.71e-3)" "unprognostic (2.46e-3)" "unprognostic (5.71e-2)" "unprognostic (3.36e-3)" "unprognostic (3.12e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-2)" "unprognostic (4.28e-1)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (6.90e-2)" "unprognostic (8.68e-2)" "prognostic favorable (1.13e-7)" "unprognostic (3.72e-2)" "unprognostic (3.03e-1)" "unprognostic (1.92e-2)" "unprognostic (9.06e-2)" 93.0 69.0 62.1 37.9 66.9 88.1 63.1 66.2 91.5 55.9 84.4 112.6 87.0 53.1 78.9 76.8 49.1 29.3 508.8 68.2 67.0 174.1 118.3 47.2 36.6 64.5 62.7 50.6 83.4 161.0 48.7 43.1 65.0 48.4 104.4 90.1 109.7 63.4 459.0 60.9 82.1 51.8 59.6 49.3 121.8 24.0 67.4 52.3 64.5 770.2 59.1 61.7 56.1 71.1 124.9 151.4 107.9 114.2 102.3 77.7 131.6 83.8 74.6 170.2 130.7 216.6 78.2 212.2 60.6 102.0 226.7 159.0 334.2 145.8 178.1 70.1 186.1 104.8 264.0 194.2 107.8 170.3 82.8 100.9 132.8 157.3 154.4 85.6 105.3 129.8 94.2 87.2 120.7 164.5 142.7 173.5 110.0 227.4 261.7 145.2 180.9 260.3 298.0 125.1 59.7 62.6 134.1 167.8 158.1 229.8 177.1 118.1 65.4 87.6 78.6 240.9 108.6 73.3 82.0 140.5 82.4 117.2 77.4 99.9 87.4 65.3 72.3 119.9 88.9 103.4 69.4 79.5 115.7 82.1 67.7 72.0 15.5 98.1 109.1 76.9 84.4 89.6 62.1 66.9 66.2 91.5 68.2 67.0 64.5 62.7 65.0 59.6 67.4 71.1 34.1 44.8 44.4 18.6 30.7 29.8 59.7 135.4 25.0 59.0 37.0 29.3 479.9 87.2 74.8 152.6 33.3 105.0 32.5 73.0 354.1 88.8 2.5 41.2 33.7 36.8 41.9 55.8 21.2 59.8 120.7 49.2 49.5 36.9 42.6 39.7 18.2 76.3 73.2 25.2 24.6 64.4 71.2 26.8 30.5 4.1 35.4 32.5 56.9 9.4 40.8 49.0 26.8 13.0 11.5 47.4 52.5 40.6 43.3 47.1 88.6 213.7 33.1 69.1 32.9 37.5 51.7 51.1 25.3 45.2 33.4 133.4 31.6 25.4 130.3 55.8 PDK3 ENSG00000067992 "Pyruvate dehydrogenase kinase 3" Q15120 X 24465270-24550466 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 71.6;Excitatory neurons: 92.8;Inhibitory neurons: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046583, HPA072492" Approved Supported Nucleoli,Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Nucleoli "HPA046583: AB_2679707, HPA072492: AB_2686526" "unprognostic (5.41e-3)" "unprognostic (5.43e-3)" "unprognostic (5.35e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-3)" "unprognostic (5.38e-2)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.51e-1)" "unprognostic (5.57e-2)" "unprognostic (1.35e-1)" "unprognostic (1.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "unprognostic (1.02e-1)" "unprognostic (2.92e-1)" "unprognostic (2.28e-2)" "unprognostic (9.43e-3)" 4.4 2.0 4.4 5.6 6.2 8.9 8.8 1.4 7.5 3.5 2.5 6.1 8.2 2.8 10.9 3.9 5.9 3.2 7.4 13.2 4.7 8.8 4.7 5.0 7.9 2.6 4.2 4.8 2.9 6.7 5.8 4.1 2.4 4.6 5.3 6.0 11.1 2.9 1.4 6.8 8.3 4.5 0.9 7.7 6.9 11.6 9.1 6.3 2.3 1.8 8.0 4.2 4.1 4.2 11.5 5.2 4.2 8.0 0.2 0.0 5.0 3.4 2.4 4.1 6.9 0.5 13.9 10.4 2.3 0.8 11.6 2.1 12.3 8.4 10.4 9.7 6.0 5.3 6.1 3.3 1.4 4.6 5.8 0.9 3.6 1.1 1.2 0.5 6.8 10.9 0.9 16.5 0.5 20.9 9.4 6.0 8.1 12.2 5.6 5.0 8.0 17.3 4.1 21.4 2.6 4.0 17.9 8.0 5.5 7.3 9.6 1.9 0.1 3.3 3.6 5.8 4.2 11.0 8.9 12.9 8.7 7.7 6.4 13.3 15.4 37.9 11.8 19.6 16.5 7.5 9.1 10.3 12.2 7.3 7.6 8.6 57.6 13.3 18.8 3.5 8.3 12.4 4.4 6.2 1.4 7.5 13.2 4.7 2.6 4.2 2.4 0.9 9.1 4.2 3.9 3.2 2.0 19.6 15.2 4.6 9.5 13.5 30.1 3.5 11.1 8.1 6.6 1.5 5.2 1.8 0.0 5.5 16.6 4.2 3.9 4.3 71.6 2.1 2.9 3.8 4.2 14.3 92.8 5.1 32.1 4.9 5.6 2.8 5.7 4.9 5.3 5.3 15.0 8.4 78.0 2.9 10.2 19.8 7.4 35.9 3.7 17.4 16.0 35.6 10.3 3.7 25.7 19.6 14.0 2.1 0.3 5.7 19.0 5.9 13.3 14.2 2.4 3.5 0.0 2.0 10.6 10.2 8.3 6.8 4.4 17.8 18.2 9.7 4.1 8.4 PDLIM3 ALP ENSG00000154553 "PDZ and LIM domain 3" Q53GG5 4 185500660-185535507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 4781.7;tongue: 1519.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 228.9;Ductal cells: 332.7;Melanocytes: 124.5;Peritubular cells: 196.0;Skeletal myocytes: 428.3;Smooth muscle cells: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 115.6;RH-30: 26.9;U-266/70: 111.2;U-266/84: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004749 Enhanced Supported Cytosol NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" Cytosol "HPA004749: AB_1855150" "unprognostic (2.75e-1)" "unprognostic (3.85e-2)" "unprognostic (3.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.08e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.15e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (9.46e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.97e-7)" "unprognostic (1.64e-3)" "unprognostic (7.77e-2)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.78e-3)" 36.3 11.5 12.7 25.7 13.3 0.0 34.5 16.8 14.8 22.7 10.9 201.2 20.8 235.3 59.1 216.2 97.5 40.1 314.0 12.0 15.7 13.9 7.7 55.2 10.7 19.9 14.2 38.1 18.7 0.8 20.7 18.8 13.8 87.0 32.5 11.2 56.3 148.1 4781.7 12.1 69.0 127.6 17.9 24.5 95.8 8.2 14.6 4.1 32.7 1519.6 26.2 141.1 40.8 14.2 0.0 0.0 0.9 0.0 0.3 0.0 0.8 0.0 0.0 0.3 1.0 1.2 0.4 0.0 0.0 0.0 6.0 0.0 0.0 0.2 0.0 0.0 15.1 0.0 0.8 4.7 13.5 0.0 0.0 8.7 0.0 2.6 0.0 12.3 9.1 0.0 0.0 0.0 115.6 0.0 0.0 0.1 2.4 0.0 1.0 0.0 26.9 0.3 0.0 0.0 17.6 13.3 0.0 0.0 7.3 2.8 0.6 0.0 7.9 0.0 7.6 0.1 7.1 111.2 34.8 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 13.3 16.8 14.8 12.0 15.7 19.9 14.2 13.8 17.9 14.6 14.2 22.4 9.6 6.0 37.2 2.6 8.9 11.4 0.7 12.5 12.1 72.8 105.7 228.9 5.7 2.2 0.0 12.5 2.5 0.6 0.2 0.0 332.7 0.4 1.4 0.8 39.0 3.5 0.0 2.5 16.7 2.7 82.9 1.1 1.1 0.0 1.3 67.5 0.9 1.6 5.0 0.5 0.5 2.0 1.8 11.7 2.6 19.6 2.3 124.5 1.0 3.2 36.4 0.0 6.6 2.6 31.2 0.0 196.0 7.3 12.2 0.0 0.2 3.2 44.3 105.2 428.3 131.4 4.0 12.6 2.4 7.1 12.2 2.5 2.4 0.3 3.9 PDZK1IP1 "DD96, MAP17, SPAP" ENSG00000162366 "PDZK1 interacting protein 1" Q13113 1 47183582-47191044 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 1047.0" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 5516.6" "Cancer enhanced" "Detected in all" "renal cancer: 340.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "EFO-21: 148.8;RPTEC TERT1: 501.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA014907 Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nuclear speckles" "HPA014907: AB_1855166" "unprognostic (2.97e-1)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" "unprognostic (9.16e-2)" "prognostic unfavorable (6.92e-4)" "unprognostic (8.14e-3)" "unprognostic (2.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.65e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (2.64e-2)" "unprognostic (7.90e-3)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (1.75e-3)" "unprognostic (1.89e-1)" 20.9 8.2 0.6 24.6 0.8 43.2 36.4 0.4 1.2 29.9 0.7 44.4 21.6 10.7 2.9 205.9 25.7 197.6 1.4 0.5 0.7 1047.0 6.8 29.5 0.4 0.4 0.5 0.7 99.9 0.0 1.1 3.9 0.7 12.1 30.9 0.0 203.4 8.6 1.6 153.1 66.4 3.1 0.4 3.7 63.4 1.4 0.9 1.9 1.5 0.6 60.2 20.0 66.6 0.4 54.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 41.5 0.0 148.8 0.0 0.0 0.7 0.0 0.5 0.0 0.6 0.0 0.6 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 2.6 501.3 0.0 0.0 0.0 0.5 4.3 0.0 0.0 1.4 0.0 0.0 0.1 1.2 0.1 0.4 0.3 0.6 0.3 0.1 0.1 0.0 0.0 3.4 0.3 0.6 1.1 0.2 0.0 0.0 0.0 1.7 0.4 0.2 0.0 6.6 0.7 0.1 1.5 1.1 144.5 0.6 0.8 0.4 1.2 0.5 0.7 0.4 0.5 0.7 0.4 0.9 0.4 1.6 76.9 47.4 0.0 31.2 14.1 13.3 489.8 7.4 0.0 152.9 105.5 0.1 303.1 413.3 233.6 0.0 0.1 1.7 118.8 414.8 1175.8 0.0 6.1 3.3 4.5 39.6 148.4 0.0 760.0 0.0 6.6 36.7 38.1 10.8 0.2 5.0 1.7 0.3 0.0 0.0 143.3 52.9 0.3 2.1 0.0 3.4 59.3 8.8 0.0 13.6 0.6 2.1 0.0 0.0 1115.2 91.0 0.0 0.1 38.9 106.2 5516.6 147.6 0.0 0.0 0.1 28.7 0.0 0.1 30.7 54.0 0.8 22.0 0.0 150.5 68.5 PDZRN3 "KIAA1095, LNX3, SEMACAP3, SEMCAP3" ENSG00000121440 "PDZ domain containing ring finger 3" Q9UPQ7 3 73382431-73624941 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 256.0;Excitatory neurons: 183.1;Inhibitory neurons: 258.3;Microglial cells: 329.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Cell line enhanced" "Detected in many" "AF22: 32.1;ASC diff: 57.0;ASC TERT1: 29.6;BJ hTERT+: 42.0;HSkMC: 41.4;U-87 MG: 30.4" "Group enriched" "Detected in many" 4 "amygdala: 15.1;basal ganglia: 8.1;cerebral cortex: 19.5;hippocampal formation: 16.1;white matter: 7.2" "Low region specificity" "Detected in many" "HPA038822, HPA061420" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA038822: AB_10675952, HPA061420: AB_2684512" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-2)" "prognostic favorable (3.35e-5)" "unprognostic (1.09e-1)" "unprognostic (5.54e-2)" "unprognostic (8.47e-2)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "prognostic favorable (4.93e-4)" "unprognostic (8.38e-2)" "prognostic favorable (3.65e-7)" "unprognostic (8.63e-3)" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (2.86e-3)" 29.9 35.7 14.9 10.2 16.3 0.0 24.0 8.5 20.9 45.2 58.0 84.0 9.2 64.1 24.5 27.8 26.7 27.4 48.0 16.7 10.6 10.7 2.1 14.9 4.5 13.0 11.8 69.4 6.9 0.8 4.6 17.5 11.0 31.7 13.9 6.3 20.9 29.0 91.8 17.3 24.4 38.4 13.1 2.4 38.7 6.4 17.1 2.9 3.6 22.4 1.4 46.7 32.0 13.2 0.0 0.0 32.1 0.1 57.0 29.6 0.1 16.9 42.0 5.0 3.2 16.2 0.0 0.1 0.1 22.8 0.8 0.0 0.0 0.0 4.8 0.0 2.2 0.0 0.0 0.0 9.5 0.0 0.1 41.4 0.0 13.8 0.1 6.0 0.0 0.0 0.0 0.0 4.9 2.1 0.0 0.2 4.6 0.0 0.2 0.0 8.4 0.1 0.0 0.0 3.7 10.5 0.0 7.8 12.7 9.2 4.5 0.0 0.0 20.6 1.5 23.6 2.2 0.7 0.0 0.2 30.4 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 14.9 16.3 8.5 20.9 16.7 10.6 13.0 11.8 11.0 13.1 17.1 13.2 5.9 0.0 0.0 256.0 0.5 2.4 9.7 0.0 1.8 19.3 7.5 7.6 65.0 0.0 0.0 5.5 6.2 0.5 2.7 1.0 1.9 0.0 0.4 2.1 45.2 2.3 21.1 0.0 183.1 0.4 0.5 25.2 2.0 3.3 0.0 35.0 0.0 0.0 0.8 0.0 258.3 9.1 0.0 0.0 2.9 1.3 23.3 0.7 16.0 329.8 0.0 22.5 0.0 21.6 5.5 0.3 0.9 28.2 0.1 10.9 0.1 7.1 0.0 1.9 0.0 4.6 19.6 0.5 6.2 2.9 1.8 0.8 0.5 12.4 3.9 6.3 PEBP4 "CORK1, hPEBP4, MGC22776" ENSG00000134020 "Phosphatidylethanolamine binding protein 4" Q96S96 8 22713251-23000000 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 382.5;skeletal muscle: 670.8;tongue: 581.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 109.0;Alveolar cells type 2: 177.3;Cardiomyocytes: 144.7;Muller glia cells: 198.7" "Group enriched" "Detected in many" 13 "lung cancer: 11.4;prostate cancer: 23.7;thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-266/70: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025064 Uncertain "Secreted in other tissues" NA NA 190000000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "HPA025064: AB_1855174" "unprognostic (1.34e-2)" "unprognostic (2.97e-2)" "unprognostic (4.11e-2)" "unprognostic (3.66e-1)" "unprognostic (3.35e-1)" "unprognostic (4.78e-2)" "unprognostic (1.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "unprognostic (8.76e-3)" "unprognostic (9.70e-8)" "unprognostic (1.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.48e-1)" "unprognostic (4.59e-1)" 1.1 3.4 12.3 0.3 16.7 0.0 3.3 21.2 9.2 0.6 19.2 0.6 0.0 0.5 382.5 6.8 2.2 1.1 200.7 8.5 15.8 2.6 0.9 115.1 0.7 15.6 20.3 1.7 34.5 82.6 13.2 0.3 20.2 45.8 0.2 12.9 21.1 2.8 670.8 1.4 0.6 0.4 8.7 0.8 9.2 6.6 28.7 1.2 56.7 581.4 1.6 0.3 0.5 15.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 12.3 16.7 21.2 9.2 8.5 15.8 15.6 20.3 20.2 8.7 28.7 15.5 1.5 109.0 177.3 15.3 2.2 1.9 1.0 0.1 0.0 10.2 5.7 4.7 144.7 0.0 7.4 1.8 2.1 0.8 1.4 0.3 3.9 0.0 34.8 1.7 2.0 2.4 0.0 0.0 10.0 9.3 0.2 10.1 2.0 7.0 7.6 0.4 3.9 0.7 1.2 10.1 9.6 0.3 2.0 0.0 0.8 28.4 3.4 1.4 1.8 6.5 0.1 198.7 5.2 6.6 0.9 0.3 0.1 10.9 1.5 23.8 0.5 5.9 2.9 8.6 0.0 25.2 2.1 14.8 1.2 0.0 0.9 0.0 1.6 1.1 0.3 1.0 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PELO ENSG00000152684 "Pelota mRNA surveillance and ribosome rescue factor" Q9BRX2 5 52787916-52804044 "Predicted intracellular proteins" "Cell cycle, Cell division, Translation regulation" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 90.7;Sertoli cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031458 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Nucleoli fibrillar center" "HPA031458: AB_10602141" "prognostic unfavorable (6.42e-4)" "unprognostic (2.44e-1)" "unprognostic (1.14e-1)" "unprognostic (2.71e-1)" "unprognostic (6.28e-3)" "unprognostic (1.71e-2)" "unprognostic (1.71e-2)" "unprognostic (6.13e-3)" "unprognostic (3.40e-1)" "unprognostic (3.72e-2)" "unprognostic (1.78e-1)" "unprognostic (4.18e-1)" "unprognostic (2.33e-2)" "unprognostic (4.56e-2)" "unprognostic (2.44e-1)" "unprognostic (1.99e-3)" "unprognostic (8.21e-2)" 9.4 17.6 5.3 5.2 5.9 8.2 7.3 5.7 5.2 6.9 4.9 11.3 4.6 9.8 7.5 6.7 7.9 6.3 10.3 5.7 6.1 9.9 10.7 11.7 6.3 5.4 6.3 5.1 5.3 7.4 6.0 11.6 5.7 6.7 3.7 4.4 4.9 6.7 12.2 8.4 6.2 9.9 5.9 12.6 7.5 4.4 6.7 4.8 7.2 8.8 3.6 8.4 6.7 5.2 18.1 18.3 8.1 14.5 14.0 10.3 7.1 20.4 22.4 19.6 23.9 18.4 13.8 5.9 36.0 22.1 29.4 14.8 11.9 17.3 16.9 6.3 16.8 6.6 15.2 15.5 42.6 12.5 7.6 13.0 17.5 22.7 18.6 16.9 11.8 8.8 8.4 18.5 17.3 14.1 13.1 7.7 6.1 3.3 19.3 4.5 10.4 17.6 14.3 8.5 13.3 10.3 10.8 13.3 11.9 13.7 12.2 4.5 11.7 11.8 11.4 12.5 26.0 7.9 10.4 7.8 22.5 11.6 10.4 22.3 5.9 7.6 4.8 3.9 5.9 4.8 6.2 5.4 6.1 3.6 5.0 4.7 19.0 4.7 2.2 2.3 4.8 4.4 5.3 5.9 5.7 5.2 5.7 6.1 5.4 6.3 5.7 5.9 6.7 5.2 49.9 9.6 7.4 0.0 9.8 46.9 53.0 24.4 14.2 16.5 12.7 18.7 12.7 17.2 20.2 9.2 2.1 35.9 10.5 8.7 35.2 31.5 65.1 18.7 23.1 50.5 10.2 8.0 0.0 25.5 90.7 36.7 9.2 27.6 1.3 11.4 40.4 18.7 20.1 8.4 0.1 16.0 14.2 6.6 23.3 9.2 17.7 15.8 7.2 0.0 7.7 15.5 6.2 0.0 0.0 24.5 6.0 12.0 14.3 36.5 12.3 29.0 16.9 11.0 85.5 13.7 56.5 22.1 13.9 14.9 35.8 53.9 23.0 18.8 11.5 38.3 PENK ENSG00000181195 Proenkephalin P01210 8 56436674-56446671 "Plasma proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 376.2;brain: 164.1;testis: 129.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 758.4;Leydig cells: 1137.9;Peritubular cells: 225.7;Spermatocytes: 274.1" "Cancer enhanced" "Detected in many" "lung cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 14.3;ASC TERT1: 8.6;BJ: 7.7;THP-1: 7.7" "Region enriched" "Detected in all" 7 "basal ganglia: 3626.9" "Region enriched" "Detected in all" 7 "basal ganglia: 923.2" "HPA013138, CAB016390" Enhanced "Secreted in other tissues" NA NA 220000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB016390: AB_2161515, HPA013138: AB_1855191" "unprognostic (6.89e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (1.17e-3)" "unprognostic (1.56e-2)" "unprognostic (3.58e-3)" "unprognostic (1.31e-2)" "unprognostic (3.60e-1)" "unprognostic (6.34e-2)" "unprognostic (5.73e-2)" "unprognostic (3.47e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.98e-3)" 8.6 376.2 29.9 4.4 164.1 0.0 4.9 45.2 45.6 9.2 0.5 23.1 1.1 8.1 0.0 1.4 7.6 12.5 25.6 2.7 74.0 0.2 0.2 3.7 0.1 81.4 15.9 29.7 1.1 0.0 17.1 2.9 51.3 22.4 2.0 0.6 2.7 23.4 3.0 0.8 4.2 4.6 54.0 0.1 10.0 129.0 38.0 0.2 1.0 5.3 0.1 0.6 6.2 10.1 0.0 0.0 0.1 0.0 14.3 8.6 0.0 7.7 2.5 1.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 29.9 164.1 45.2 45.6 2.7 74.0 81.4 15.9 51.3 54.0 38.0 10.1 0.2 0.0 1.5 0.3 0.5 0.1 0.2 758.4 0.0 0.3 0.1 0.6 0.8 0.0 8.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 85.7 0.1 3.1 0.9 0.0 0.0 0.4 0.0 0.1 16.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.4 0.0 2.0 0.0 0.7 60.8 1137.9 1.2 0.0 1.9 0.0 0.0 0.0 0.5 0.4 0.0 0.0 225.7 0.0 0.2 0.0 0.0 3.6 0.0 6.6 1.7 1.2 274.1 19.1 0.1 0.4 0.0 0.2 3.1 0.0 0.0 PFKFB3 ENSG00000170525 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" Q16875 10 6144934-6254644 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 334.6;skeletal muscle: 621.3" "Cell type enhanced" "Detected in many" "Astrocytes: 153.8;Collecting duct cells: 195.0;Langerhans cells: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 26.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 296.2;RPTEC TERT1: 181.8;T-47d: 192.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008266, CAB020795, HPA043889" Uncertain Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB020795: , HPA008266: AB_1855239, HPA043889: AB_2678717" "unprognostic (1.61e-1)" "unprognostic (5.08e-3)" "unprognostic (2.89e-2)" "unprognostic (6.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (1.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (3.30e-2)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.87e-7)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" 334.6 22.7 66.1 72.2 81.2 246.0 153.8 75.4 66.6 30.2 22.1 22.2 19.4 24.0 11.1 51.3 37.7 59.9 21.9 62.8 105.8 243.9 32.8 67.7 24.5 145.7 100.9 24.2 21.0 10.1 39.6 20.0 100.9 20.2 8.9 31.5 40.4 49.5 621.3 53.6 22.9 16.9 90.1 50.2 26.1 13.9 91.8 15.1 10.9 30.4 28.2 63.9 40.3 105.6 22.0 296.2 23.1 18.8 85.2 10.5 12.2 31.6 22.5 22.9 35.5 14.1 78.0 37.2 20.2 13.8 18.0 69.0 24.9 50.2 26.3 44.6 17.3 22.1 16.2 5.2 7.2 21.6 32.2 7.6 16.4 39.5 9.5 58.3 44.9 25.6 16.6 13.6 18.6 35.7 15.3 20.3 22.5 31.1 20.5 34.3 11.3 14.7 181.8 11.1 21.9 8.9 22.9 24.7 45.8 39.5 192.0 25.2 57.0 23.9 22.0 3.1 38.7 27.8 10.4 33.7 65.8 25.0 37.4 2.9 7.5 7.7 2.2 9.2 5.7 1.8 4.2 2.9 4.7 1.6 3.0 3.0 26.4 1.2 5.5 2.9 4.3 4.3 66.1 81.2 75.4 66.6 62.8 105.8 145.7 100.9 100.9 90.1 91.8 105.6 37.1 76.9 55.1 153.8 27.2 102.6 16.7 21.5 37.5 6.4 37.1 36.8 19.5 22.8 32.1 195.0 52.1 0.4 37.0 14.9 0.0 54.7 5.0 41.1 18.9 32.9 8.5 1.3 42.8 25.7 6.9 30.8 33.1 64.3 44.2 72.5 8.9 15.8 20.6 6.7 19.4 6.6 18.3 88.0 132.3 9.5 2.8 122.2 46.2 41.2 19.6 0.3 4.1 14.1 31.9 59.6 5.2 7.2 25.3 4.2 5.4 2.4 19.2 1.9 0.0 58.5 24.4 0.6 2.5 20.9 63.9 1.0 61.7 12.4 8.1 14.7 PGAP1 "Bst1, FLJ12377, SPG67" ENSG00000197121 "Post-GPI attachment to proteins inositol deacylase 1" Q75T13 2 196833004-196927796 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 19.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 89.6;Inhibitory neurons: 104.5;Oligodendrocyte precursor cells: 130.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.21e-1)" "unprognostic (9.15e-2)" "unprognostic (5.89e-2)" "unprognostic (3.82e-2)" "unprognostic (1.81e-1)" "unprognostic (5.55e-3)" "unprognostic (2.50e-2)" "unprognostic (6.95e-2)" "unprognostic (6.51e-2)" "unprognostic (1.41e-2)" "unprognostic (2.59e-3)" "unprognostic (9.61e-2)" "unprognostic (7.16e-3)" "unprognostic (1.21e-1)" "unprognostic (7.88e-2)" "unprognostic (9.03e-3)" "unprognostic (1.91e-2)" 3.9 8.4 10.2 1.1 11.7 2.0 3.8 8.9 12.1 3.5 4.6 3.0 3.7 3.0 3.1 3.5 2.8 1.5 3.2 7.9 19.2 1.7 1.2 4.5 1.1 6.8 15.1 9.3 4.4 2.8 9.2 3.3 7.3 3.2 2.8 13.0 2.2 2.2 1.4 12.3 4.3 2.2 4.4 1.4 2.0 1.5 17.8 1.7 2.1 1.4 1.1 3.0 3.9 5.8 1.5 0.6 15.2 8.3 6.8 4.1 2.5 1.9 1.4 1.1 1.3 0.8 1.6 1.8 2.4 2.8 2.4 2.8 4.0 4.3 1.7 9.0 5.2 1.2 4.0 4.1 1.8 2.6 2.0 3.0 3.0 1.9 2.2 7.9 6.6 5.9 0.3 3.0 4.2 0.6 2.4 3.3 7.1 2.4 3.5 3.7 3.8 0.5 2.4 13.8 12.6 10.0 1.3 1.9 2.4 9.0 1.9 1.0 7.6 5.1 2.2 2.5 2.6 2.7 1.5 2.4 3.9 1.2 5.1 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.7 0.7 0.1 0.2 0.6 0.5 0.2 0.1 0.0 0.0 0.9 0.0 10.2 11.7 8.9 12.1 7.9 19.2 6.8 15.1 7.3 4.4 17.8 5.8 9.3 3.2 2.6 37.9 12.7 34.4 13.5 21.4 30.1 43.3 5.4 5.6 6.8 2.8 6.9 25.8 25.0 37.4 4.6 5.8 0.0 1.4 8.3 11.9 14.5 9.7 38.9 3.2 89.6 3.7 9.1 15.8 14.3 4.3 4.5 8.8 4.2 4.4 6.2 13.5 104.5 13.6 8.2 1.9 14.9 4.8 14.3 3.0 7.2 23.4 1.3 17.5 3.1 130.2 58.7 0.9 8.2 15.8 8.2 11.4 12.4 1.6 16.7 41.1 6.6 12.0 33.8 11.0 8.2 23.4 30.0 15.9 18.5 8.1 24.0 11.9 PGBD5 "DKFZp761A0620, FLJ11413" ENSG00000177614 "PiggyBac transposable element derived 5" Q8N414 1 230314490-230426332 "Disease related genes, Predicted intracellular proteins" Transposition "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.8;pancreas: 20.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.6;Excitatory neurons: 83.3;Inhibitory neurons: 78.4;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 17.7;basal ganglia: 18.5;cerebral cortex: 35.9;hippocampal formation: 41.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 30.7;GAMG: 15.0;NTERA-2: 30.3;RH-30: 16.4;SCLC-21H: 41.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065010 Supported Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA065010: AB_2685402" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.61e-2)" "prognostic unfavorable (8.78e-5)" "unprognostic (1.44e-2)" "unprognostic (4.66e-2)" "unprognostic (4.91e-2)" "unprognostic (3.97e-1)" "unprognostic (1.15e-1)" "unprognostic (7.48e-3)" "unprognostic (2.57e-1)" "unprognostic (3.29e-2)" "unprognostic (6.69e-2)" "unprognostic (2.12e-1)" "unprognostic (3.13e-3)" "unprognostic (2.51e-1)" 0.4 9.4 17.7 0.4 18.5 0.1 0.4 1.1 35.9 18.1 0.0 1.0 0.5 4.6 0.0 1.2 4.9 1.7 13.1 41.8 0.0 1.0 3.1 1.3 0.5 0.9 0.0 0.3 20.3 1.3 5.8 2.1 1.4 0.8 0.7 6.9 5.2 0.7 2.6 0.7 0.5 2.4 0.0 2.2 1.1 5.2 0.1 3.0 5.2 5.1 4.6 0.9 2.6 6.6 0.0 0.0 7.6 0.1 0.1 0.0 0.6 0.5 0.0 0.2 0.0 6.8 0.0 30.7 2.8 0.1 15.0 5.7 2.4 0.0 0.0 0.1 2.6 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.2 1.5 0.3 6.2 30.3 0.0 0.2 0.0 16.4 4.9 3.5 0.0 41.4 7.7 1.0 0.1 0.4 0.6 0.4 10.5 0.0 0.0 2.5 0.0 2.5 12.7 10.3 0.0 0.1 2.6 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 17.7 18.5 1.1 35.9 41.8 0.0 0.9 0.0 1.4 0.0 0.1 6.6 0.3 0.0 1.9 18.9 0.3 0.1 0.7 0.1 0.0 26.6 1.3 0.6 9.0 4.3 0.4 0.0 20.9 0.1 0.3 0.4 0.0 10.3 0.9 1.4 3.0 0.3 9.1 0.0 83.3 5.8 0.2 0.8 0.0 2.9 10.8 1.9 0.4 4.1 11.5 21.9 78.4 0.4 0.0 3.8 0.3 0.9 0.0 0.9 1.8 4.7 0.1 2.8 0.0 16.1 48.0 5.5 0.3 0.0 0.0 2.1 0.0 0.8 0.9 10.8 0.0 6.4 0.8 0.7 1.8 0.0 0.0 0.3 0.5 2.8 0.6 1.9 PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420511 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 400.2;esophagus: 572.4" "Cell type enhanced" "Detected in all" "monocytes: 214.9;Squamous epithelial cells: 496.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1060.2;classical monocyte: 321.0;eosinophil: 1074.7;neutrophil: 332.6" "Group enriched" "Detected in all" 5 "granulocytes: 1074.7;monocytes: 321.0" "Cell line enhanced" "Detected in all" "A549: 1445.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Intermediate filaments,Cytosol" No No 41000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments, Cytosol" "HPA031314: AB_10610278, HPA031315: AB_2673825" "unprognostic (4.65e-2)" "unprognostic (2.58e-1)" "unprognostic (8.65e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (1.40e-2)" "unprognostic (4.92e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" 115.8 51.0 49.5 59.8 49.2 400.2 89.0 52.9 49.3 75.9 52.5 52.9 91.6 23.1 41.9 572.4 30.0 94.2 34.3 47.4 54.3 53.2 81.3 88.5 38.1 57.0 54.6 35.7 32.0 52.7 43.8 47.4 55.4 30.4 46.3 49.1 133.7 22.9 34.7 50.0 70.7 35.0 49.7 110.4 61.4 68.3 59.2 53.6 71.8 28.2 73.8 61.8 126.9 52.0 191.5 1445.2 319.3 340.6 445.4 274.0 71.8 124.8 185.9 144.4 195.3 219.2 190.4 163.5 151.0 109.2 202.4 148.0 225.6 192.1 96.4 127.5 199.9 227.8 264.3 452.1 136.3 390.9 249.7 196.5 92.2 229.4 55.5 186.9 344.0 223.0 305.3 145.7 183.5 202.5 321.4 179.4 194.7 221.0 109.1 252.7 298.1 312.2 199.6 105.5 178.0 154.1 99.1 153.5 137.5 196.7 173.3 308.5 369.3 81.1 149.6 98.3 134.5 111.6 256.0 323.5 175.1 393.9 73.6 1060.2 321.0 1074.7 23.2 137.7 26.5 33.1 21.4 20.8 144.6 23.3 21.1 22.3 332.6 19.7 105.6 98.7 23.1 225.0 49.5 49.2 52.9 49.3 47.4 54.3 57.0 54.6 55.4 49.7 59.2 52.0 7.4 19.2 35.0 11.8 24.9 13.0 30.8 78.0 70.6 7.8 30.4 18.5 11.0 50.1 73.2 20.2 18.8 134.6 29.8 24.3 52.8 52.1 10.9 17.8 18.6 22.6 23.4 55.7 8.6 40.3 40.7 37.5 41.8 24.5 25.9 53.9 16.1 66.2 134.6 1.7 12.6 30.2 59.0 163.8 30.9 13.4 17.1 150.9 17.8 4.7 214.9 16.5 10.3 13.6 9.0 38.7 26.7 10.5 41.9 43.5 66.6 55.1 46.2 20.2 19.7 23.4 21.5 41.5 38.4 496.0 16.6 81.3 19.4 27.3 51.7 76.1 PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297862-153310718 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 38.9;skin 1: 73.7;vagina: 21.4" "Cell type enriched" "Detected in single" 12 "Squamous epithelial cells: 4.9" "Cancer enhanced" "Detected in many" "cervical cancer: 8.9;head and neck cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "HaCaT: 3.8;HDLM-2: 1.6;hTCEpi: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA030369: AB_10603984" "unprognostic (6.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-2)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (3.88e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 73.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 7.6 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330316-74398433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 90.1;Exocrine glandular cells: 124.5;Pancreatic endocrine cells: 140.1;Respiratory ciliated cells: 95.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 16.6;LHCN-M2: 19.9;RH-30: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056995, HPA060948" Enhanced Approved Mitochondria No No 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 1: Pancreatic cells - Digestion" Mitochondria "HPA056995: AB_2683305, HPA060948: AB_2684394" "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" "unprognostic (7.28e-3)" "unprognostic (8.91e-2)" "unprognostic (6.16e-2)" "unprognostic (1.55e-1)" "unprognostic (7.16e-6)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (5.97e-3)" "unprognostic (1.70e-2)" "unprognostic (2.98e-1)" "unprognostic (9.33e-3)" "unprognostic (3.71e-1)" "unprognostic (1.97e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-2)" 1.9 2.6 17.6 3.7 22.1 3.2 1.9 0.0 21.5 4.9 0.0 3.2 1.3 4.4 0.8 1.0 3.2 3.3 1.1 23.1 16.2 1.6 1.0 1.8 3.0 1.9 4.5 0.9 3.1 0.7 3.9 1.1 2.2 2.9 3.5 2.6 2.6 1.3 5.9 0.7 1.5 4.0 0.3 1.5 2.1 1.3 5.7 8.1 2.7 11.1 2.7 6.4 1.9 7.8 2.7 3.8 14.5 2.7 4.3 1.9 0.4 3.5 2.6 3.0 3.3 1.4 6.8 0.3 8.5 2.3 5.3 1.3 2.9 0.7 2.8 1.1 1.5 2.1 2.0 1.1 0.5 2.4 3.2 1.0 0.7 6.8 1.2 3.2 16.6 5.0 2.8 1.8 19.9 0.3 9.9 2.1 2.9 2.0 3.3 3.1 18.9 0.1 7.8 0.5 0.7 2.9 5.7 1.3 2.6 3.9 0.2 0.4 14.0 6.6 6.0 2.7 3.7 2.4 3.8 0.3 0.6 3.4 1.6 1.2 0.3 0.5 0.9 0.3 1.3 1.1 1.6 1.1 0.2 0.8 1.5 0.8 0.3 1.4 0.2 0.8 3.9 0.5 17.6 22.1 0.0 21.5 23.1 16.2 1.9 4.5 2.2 0.3 5.7 7.8 19.6 6.4 6.4 8.5 20.9 7.6 41.2 14.3 10.8 23.9 26.5 19.4 7.3 17.2 30.2 9.2 16.7 0.6 17.6 13.8 5.9 37.4 14.1 28.1 23.5 32.1 11.9 47.5 90.1 124.5 5.3 21.0 7.1 25.5 8.2 16.1 29.3 1.0 5.4 8.4 64.8 16.2 18.3 23.0 21.6 3.6 2.5 9.9 16.0 20.6 4.6 4.4 12.3 14.6 7.1 140.1 9.3 3.8 13.4 50.4 4.2 5.3 95.4 11.0 26.3 21.3 16.7 34.2 21.2 9.0 5.3 0.1 25.0 8.8 20.9 55.6 PGM5 PGMRP ENSG00000154330 "Phosphoglucomutase 5" Q15124 9 68328308-68531061 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell adhesion, Glucose metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 269.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107.2;Endothelial cells: 36.6;Hepatic stellate cells: 39.3;Microglial cells: 124.6;Sertoli cells: 52.6;Smooth muscle cells: 35.9" "Cancer enhanced" "Detected in many" "prostate cancer: 16.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "neutrophil: 4.8" "Lineage enriched" "Detected in single" 48 "granulocytes: 4.8" "Group enriched" "Detected in some" 5 "hTERT-RPE1: 28.7;PC-3: 56.5;RH-30: 38.8;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034397, HPA046329, HPA067102" Enhanced Uncertain Cytosol NA NA 450000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB034397: AB_1118633, HPA046329: AB_2679625, HPA067102: AB_2732758" "unprognostic (3.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.98e-3)" "unprognostic (5.75e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-4)" "unprognostic (1.22e-3)" "unprognostic (2.79e-1)" "unprognostic (5.28e-3)" "unprognostic (4.78e-2)" "unprognostic (2.28e-2)" "prognostic favorable (1.83e-5)" "unprognostic (3.04e-2)" "unprognostic (2.91e-1)" "unprognostic (2.48e-1)" "unprognostic (4.73e-2)" 28.9 61.0 3.7 12.6 4.1 0.0 21.0 5.8 3.8 51.7 3.3 269.4 15.4 154.0 40.8 98.6 96.5 19.6 126.1 3.1 4.1 11.5 5.1 14.6 5.8 4.6 4.0 19.8 2.7 5.0 4.3 5.8 4.3 159.0 34.2 8.0 6.7 214.0 37.5 11.1 72.0 132.5 4.7 10.8 65.2 3.0 4.6 2.9 13.1 30.5 2.9 216.7 40.6 4.6 0.2 0.2 0.0 0.0 0.7 0.0 0.3 8.2 6.3 3.8 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 9.2 0.0 9.4 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 28.7 0.0 0.0 0.0 0.1 0.0 4.1 0.1 0.7 0.0 0.0 56.5 0.0 38.8 1.8 1.5 0.0 0.0 0.2 0.1 47.8 2.8 1.2 0.0 0.0 0.1 0.0 5.7 0.3 0.3 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 3.7 4.1 5.8 3.8 3.1 4.1 4.6 4.0 4.3 4.7 4.6 4.6 21.6 0.0 1.7 0.7 0.2 2.3 5.6 0.0 0.6 25.3 0.2 1.5 107.2 2.8 1.8 12.9 4.2 0.0 0.1 0.1 1.9 0.1 1.8 3.7 2.8 36.6 0.0 4.0 1.4 0.0 0.2 12.4 0.0 1.1 0.0 18.7 39.3 0.1 0.1 0.0 1.7 2.7 0.0 4.0 2.8 0.5 8.1 2.1 3.6 124.6 1.0 8.3 0.0 1.0 2.3 0.1 0.1 4.9 0.0 2.1 0.8 1.2 0.8 1.9 52.6 1.7 35.9 0.1 0.2 0.4 2.4 0.0 0.6 30.0 1.6 1.5 PHC1 "EDR1, HPH1, RAE28" ENSG00000111752 "Polyhomeotic homolog 1" P78364 12 8913896-8941467 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, DNA-binding" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "BEWO: 141.8;NTERA-2: 492.6;SuSa: 178.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006973 Approved Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA006973: AB_1855278" "unprognostic (4.00e-2)" "unprognostic (1.79e-1)" "unprognostic (2.57e-1)" "unprognostic (1.73e-1)" "unprognostic (4.21e-3)" "unprognostic (7.46e-2)" "unprognostic (1.33e-1)" "unprognostic (1.59e-1)" "unprognostic (2.52e-1)" "unprognostic (1.47e-1)" "unprognostic (4.79e-3)" "unprognostic (1.69e-1)" "unprognostic (1.34e-2)" "unprognostic (7.55e-2)" "unprognostic (2.47e-1)" "unprognostic (9.27e-2)" "unprognostic (3.63e-2)" 20.1 18.1 22.9 17.7 21.1 7.5 23.1 26.1 21.8 46.8 31.3 32.1 6.9 42.0 13.3 20.7 44.6 15.7 20.4 21.7 21.4 24.9 6.9 21.4 16.1 20.5 22.9 47.2 25.5 26.4 75.7 14.1 19.3 31.7 9.4 40.0 23.6 20.2 16.1 10.7 21.0 22.4 19.2 22.2 22.3 43.3 20.8 28.1 44.3 10.3 14.6 28.0 26.9 19.8 6.6 11.1 46.5 43.0 13.8 14.5 141.8 6.6 13.7 11.3 14.7 7.4 10.5 17.4 5.7 11.3 17.4 5.8 12.9 15.4 15.2 60.8 7.5 22.8 14.5 7.5 15.0 12.4 38.5 18.0 8.0 18.1 18.1 36.2 13.7 19.8 4.6 6.4 11.5 8.2 15.8 22.1 492.6 2.5 3.7 25.1 31.3 0.9 12.3 29.0 9.0 32.1 10.4 23.4 17.4 178.3 3.4 12.4 7.8 20.8 34.5 13.2 9.6 12.8 8.9 24.9 9.3 6.7 14.4 0.6 0.2 0.0 0.8 1.1 0.5 1.1 1.2 1.5 0.1 0.9 1.2 0.9 0.0 0.8 2.8 1.2 0.8 0.8 22.9 21.1 26.1 21.8 21.7 21.4 20.5 22.9 19.3 19.2 20.8 19.8 11.9 16.0 19.8 48.3 7.7 2.4 5.5 4.6 9.1 24.2 10.8 11.2 0.5 11.5 13.1 9.2 27.1 5.9 10.1 0.8 1.9 5.4 26.4 20.0 17.4 11.0 11.4 9.5 36.4 5.2 11.5 11.8 5.1 10.6 19.0 15.5 8.6 2.0 4.4 16.8 44.0 2.7 4.1 5.4 3.9 17.6 14.3 6.0 7.2 12.2 3.2 17.7 7.2 23.1 13.0 4.6 1.9 12.0 3.0 4.5 0.7 5.3 19.2 36.8 0.0 15.8 12.2 17.7 25.1 10.2 2.4 5.1 11.2 8.7 2.0 4.9 PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 204.8;Leydig cells: 205.9;Oligodendrocytes: 67.3;Peritubular cells: 149.7" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cell line enriched" "Detected in some" 6 "JURKAT: 29.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" 57.8 3.5 12.2 3.1 17.7 0.2 66.1 14.3 15.1 140.6 7.9 11.6 1.5 5.7 29.0 10.6 15.0 46.4 127.7 10.1 16.1 1.5 0.7 11.4 2.2 15.3 14.2 3.4 5.6 0.9 8.4 2.4 15.8 31.3 7.9 0.0 14.0 34.2 15.1 51.7 4.5 8.4 13.4 1.3 22.1 14.7 16.4 2.4 23.2 33.6 6.0 116.1 127.6 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.9 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 29.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.8 0.6 19.7 5.7 0.0 1.3 6.4 2.2 0.5 13.5 0.0 0.5 66.1 3.3 12.2 17.7 14.3 15.1 10.1 16.1 15.3 14.2 15.8 13.4 16.4 19.3 10.9 0.0 1.5 3.3 0.7 21.5 0.1 0.0 0.6 0.0 0.4 0.4 4.5 0.0 0.6 1.8 0.0 0.0 0.4 0.0 1.9 0.1 10.8 0.1 0.2 11.0 0.0 0.0 0.1 0.0 0.0 204.8 4.1 0.1 0.0 0.0 10.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 39.6 19.0 205.9 1.9 10.6 3.7 0.0 0.0 0.0 0.0 67.3 0.1 0.0 149.7 0.6 0.1 0.0 0.2 0.0 0.0 0.0 7.7 4.2 2.4 1.3 0.4 18.5 0.1 3.5 0.3 0.0 0.2 PIF1 "C15orf20, FLJ22692" ENSG00000140451 "PIF1 5'-to-3' DNA helicase" Q9H611 15 64815632-64825668 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.8" "Cell type enhanced" "Detected in many" "Early spermatids: 21.3;Erythroid cells: 17.7;Granulosa cells: 15.1;NK-cells: 15.5;Theca cells: 18.3" "Cancer enhanced" "Detected in many" "testis cancer: 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB018701 Supported Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB018701: AB_2164654" "unprognostic (1.99e-1)" "unprognostic (6.11e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.62e-1)" "unprognostic (8.33e-3)" "unprognostic (8.66e-4)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (6.68e-2)" "unprognostic (2.38e-2)" "unprognostic (3.27e-2)" "unprognostic (0.00e+0)" "unprognostic (2.96e-3)" "unprognostic (1.78e-1)" "unprognostic (9.61e-2)" "unprognostic (5.95e-2)" 0.7 1.0 0.8 2.6 0.8 3.8 0.4 0.7 1.3 0.9 0.7 2.4 1.9 0.8 0.1 3.1 0.7 0.8 0.9 0.7 1.2 0.6 0.6 1.0 4.6 1.4 1.0 0.4 0.2 0.2 0.5 0.9 1.1 1.7 1.0 0.1 0.6 0.7 0.3 1.0 2.6 1.2 0.9 4.8 1.8 2.5 1.2 3.6 0.5 0.1 3.3 1.5 1.4 0.8 7.7 8.7 21.1 8.6 3.7 4.3 7.8 7.4 3.9 7.3 5.6 14.0 12.6 9.3 3.0 3.6 6.8 20.9 21.8 6.2 2.7 14.8 8.0 10.8 28.5 10.2 1.9 4.3 8.4 2.5 0.0 3.2 2.6 1.8 7.5 13.6 7.2 18.0 7.0 6.7 4.7 17.9 17.2 9.7 6.0 9.7 7.0 13.0 4.1 4.3 8.7 5.6 5.7 6.3 3.3 9.2 7.0 4.7 5.2 4.4 22.6 7.0 14.0 14.3 14.3 9.0 4.2 18.8 6.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.8 0.7 1.3 0.7 1.2 1.4 1.0 1.1 0.9 1.2 0.8 1.2 0.0 1.1 3.6 6.5 1.9 0.8 0.6 0.0 0.5 0.6 0.6 1.9 0.0 0.1 0.0 0.0 5.1 7.5 3.2 0.0 0.0 21.3 0.4 4.4 2.3 0.0 17.7 2.6 0.0 6.5 5.6 3.6 0.7 0.0 15.1 5.3 0.5 5.8 0.0 1.0 2.4 0.0 5.1 2.0 2.3 1.5 4.5 0.0 1.9 0.1 0.8 15.5 3.5 0.1 0.2 0.1 2.2 9.7 1.1 0.2 0.1 0.1 1.2 6.6 4.2 3.5 0.8 2.0 1.6 1.0 1.1 7.5 18.3 6.2 1.3 PIGN "MCD4, PIG-N" ENSG00000197563 "Phosphatidylinositol glycan anchor biosynthesis class N" O95427 18 61905255-62187118 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 323.7;Alveolar cells type 2: 372.2;Club cells: 138.4;granulocytes: 159.0;Oligodendrocytes: 123.2;Respiratory ciliated cells: 145.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039922, HPA040374" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cytosol" "HPA039922: AB_10805597, HPA040374: AB_10794738" "unprognostic (1.93e-2)" "unprognostic (1.71e-1)" "prognostic favorable (6.51e-4)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (3.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.99e-1)" "unprognostic (1.64e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.81e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-2)" "unprognostic (1.08e-1)" "unprognostic (5.75e-2)" "unprognostic (2.71e-1)" 10.0 10.3 9.8 10.9 14.3 16.9 15.9 49.4 47.1 11.8 3.2 16.2 14.0 11.1 11.9 22.7 8.9 12.6 13.5 13.1 9.6 11.9 18.1 9.9 10.5 4.1 0.1 12.1 15.8 16.0 4.3 17.5 9.6 17.3 18.4 38.9 14.8 7.5 13.4 20.1 13.3 8.9 0.0 10.0 21.1 19.8 11.4 12.3 16.9 10.8 12.8 14.9 7.7 49.7 31.6 19.0 18.4 23.0 23.1 31.4 24.3 32.3 25.7 21.2 24.9 24.4 31.9 36.0 44.0 25.0 18.3 44.6 26.0 27.8 32.9 30.3 16.9 21.6 29.6 19.7 16.8 46.0 24.6 18.5 18.1 21.0 24.5 22.3 27.0 25.3 26.1 50.8 23.3 28.2 22.8 13.5 29.9 25.3 17.3 24.1 35.1 35.7 25.5 48.5 20.8 21.4 42.5 29.0 13.6 50.9 46.1 28.6 29.8 41.0 28.2 15.4 23.5 54.3 53.8 17.4 22.5 25.7 40.9 10.1 7.5 6.1 6.9 6.6 7.2 7.9 7.1 6.9 8.9 8.8 8.0 8.4 9.6 12.1 7.8 10.2 6.5 3.7 9.8 14.3 49.4 47.1 13.1 9.6 4.1 0.1 9.6 0.0 11.4 49.7 8.9 323.7 372.2 52.5 9.7 8.0 8.9 8.4 10.2 7.2 16.3 9.4 10.4 12.8 138.4 11.0 4.2 9.6 14.1 11.6 1.9 11.0 6.4 9.1 16.2 24.7 6.7 16.6 54.5 9.5 11.5 26.6 10.2 11.5 159.0 19.3 10.0 12.0 10.1 6.7 41.3 11.6 10.2 9.2 4.0 6.5 7.2 26.9 3.6 44.0 7.9 7.3 3.1 57.8 123.2 10.9 9.4 3.8 8.2 11.7 5.6 5.0 145.5 6.6 6.6 6.8 6.7 20.7 7.3 17.4 17.0 10.4 18.5 10.5 12.3 12.1 PIGR ENSG00000162896 "Polymeric immunoglobulin receptor" P01833 1 206928522-206946466 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2641.0;salivary gland: 1645.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7090.1;Intestinal goblet cells: 2361.1;Paneth cells: 3208.3;Proximal enterocytes: 1558.6;Undifferentiated cells: 4954.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 731.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "EFO-21: 36.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006154, CAB009454, HPA012012" Enhanced "Secreted to digestive system" NA NA 1300000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 9: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB009454: AB_2164819, HPA006154: AB_1855370, HPA012012: AB_1855371" "prognostic favorable (1.22e-5)" "unprognostic (7.42e-2)" "unprognostic (4.78e-3)" "prognostic favorable (2.57e-4)" "unprognostic (2.31e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (2.13e-1)" "prognostic favorable (5.08e-5)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (6.92e-3)" "unprognostic (3.39e-2)" 2.4 0.5 0.4 187.3 0.2 0.3 131.0 0.5 0.4 547.0 0.2 1693.4 2641.0 20.5 0.2 12.4 3.6 455.0 0.5 0.4 0.2 108.9 34.5 101.6 1.7 0.2 0.2 0.6 13.3 0.1 1.3 0.3 0.4 13.6 1222.6 0.1 1645.1 5.3 0.3 0.6 809.8 39.1 0.1 0.8 414.6 0.3 0.6 0.4 0.2 0.0 0.6 80.3 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 36.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 1.9 0.3 0.0 0.0 0.2 0.0 6.9 0.2 1.7 0.8 2.5 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.3 0.6 0.3 0.4 1.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.3 0.8 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.0 0.4 0.2 0.5 0.4 0.4 0.2 0.2 0.2 0.4 0.1 0.6 0.6 2.1 93.0 604.3 0.0 22.1 0.3 4.0 106.6 0.0 0.0 392.4 192.0 1.4 876.4 638.4 108.5 0.0 0.1 2.5 7090.1 17.6 92.5 0.0 65.9 14.6 5.4 426.4 2.7 0.0 64.5 0.0 4.7 482.1 120.1 52.0 0.0 1.8 28.0 0.4 0.0 0.0 2361.1 59.0 2.2 1.1 0.0 0.0 5.7 1.8 0.0 0.6 0.0 0.0 0.0 0.0 221.5 3208.3 0.0 0.7 53.9 1558.6 328.4 415.4 0.0 0.0 0.0 21.0 0.0 0.0 6.9 0.0 0.0 15.6 0.1 4954.6 761.3 PITPNA "PITPN, VIB1A" ENSG00000174238 "Phosphatidylinositol transfer protein alpha" Q00169 17 1517718-1562792 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000528 Uncertain Approved Vesicles,Cytosol NA NA 190000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" Cytosol Vesicles "HPA000528: AB_1079622" "unprognostic (1.54e-1)" "unprognostic (6.63e-2)" "unprognostic (2.43e-1)" "prognostic favorable (2.29e-4)" "unprognostic (7.88e-2)" "unprognostic (8.89e-3)" "unprognostic (2.37e-1)" "unprognostic (1.37e-1)" "unprognostic (7.33e-2)" "unprognostic (3.17e-2)" "prognostic favorable (1.80e-6)" "unprognostic (7.41e-2)" "prognostic favorable (9.35e-4)" "unprognostic (1.72e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-2)" "unprognostic (6.81e-3)" 42.5 36.8 41.7 61.0 45.4 93.6 41.7 46.6 56.2 50.7 51.0 47.2 56.7 55.3 58.8 76.6 65.9 45.4 39.1 43.8 50.5 40.0 39.0 46.9 40.4 62.4 45.4 32.1 33.9 60.8 33.1 50.2 58.4 54.2 55.6 47.6 84.1 61.7 24.7 93.2 88.9 54.3 41.9 42.4 40.5 44.8 52.2 33.2 64.7 22.7 57.1 51.9 41.8 43.0 64.9 70.5 70.5 61.0 72.1 78.8 110.7 68.9 75.8 70.6 50.9 78.7 25.7 81.8 62.4 94.0 45.4 79.5 64.2 68.4 97.0 68.3 69.2 44.7 61.4 37.0 70.6 31.1 51.6 58.9 90.6 70.5 73.1 74.4 118.4 67.1 63.3 44.9 74.8 36.5 80.1 28.5 49.3 103.4 34.1 63.8 27.2 46.9 70.5 73.5 25.2 55.2 83.2 59.1 51.4 70.5 52.2 24.7 113.8 44.8 39.5 126.4 95.5 27.2 49.8 28.8 77.4 47.9 58.4 3.7 2.4 3.2 2.1 2.7 4.0 4.3 3.1 2.8 3.5 3.1 2.9 2.6 8.0 3.7 1.9 2.7 5.2 1.7 41.7 45.4 46.6 56.2 43.8 50.5 62.4 45.4 58.4 41.9 52.2 43.0 29.3 35.3 35.0 28.7 14.1 31.0 17.5 12.0 12.0 36.4 30.0 30.2 23.9 17.2 17.1 25.8 8.4 43.4 26.9 41.2 13.7 16.0 12.0 50.5 48.4 31.4 22.1 15.6 42.4 18.5 47.3 19.1 13.3 36.5 19.0 16.8 34.6 30.2 40.5 40.4 46.3 27.7 10.2 29.9 49.7 16.8 12.5 36.4 19.6 36.5 36.6 40.2 13.4 12.1 16.0 26.0 22.9 21.8 15.7 33.0 78.0 16.3 21.7 18.4 6.6 18.8 45.1 35.8 34.7 37.8 41.8 120.0 14.9 24.7 25.3 27.0 PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697261 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1255.9;Inhibitory neurons: 330.9;Oligodendrocyte precursor cells: 281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol Nucleoplasm "HPA026563: AB_1855409, HPA031250: AB_2673808" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.14e-3)" "unprognostic (4.17e-2)" "prognostic favorable (4.85e-5)" "unprognostic (6.57e-2)" "unprognostic (6.32e-3)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "unprognostic (5.70e-2)" "unprognostic (2.31e-2)" "unprognostic (1.34e-2)" "unprognostic (9.83e-2)" "unprognostic (7.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.16e-2)" 25.7 8.9 27.2 5.6 30.1 3.8 18.6 23.5 26.9 8.7 13.2 7.6 1.5 7.8 3.8 9.8 10.9 3.8 13.3 22.7 31.2 21.8 9.8 15.1 8.8 38.4 41.0 15.2 23.1 1.8 13.7 6.0 28.2 11.9 2.2 15.0 14.1 4.4 5.4 4.9 8.7 3.5 28.7 9.4 12.6 2.5 42.7 8.4 9.0 5.0 7.4 12.0 9.2 20.1 4.2 1.0 4.5 6.8 2.8 5.1 3.9 6.0 2.9 0.8 0.4 0.0 6.4 4.6 1.4 3.6 1.7 2.0 6.7 6.0 1.1 9.3 3.0 0.7 7.6 3.4 0.7 1.4 9.8 3.6 2.2 0.9 2.5 0.5 3.2 6.5 0.3 16.9 2.3 7.0 10.9 2.8 6.6 1.8 7.7 15.2 0.9 4.2 9.7 5.4 4.7 13.0 1.7 3.3 4.1 4.8 3.0 4.7 3.7 1.8 1.0 2.4 2.9 13.2 6.2 3.7 14.4 4.6 1.6 0.7 1.4 10.3 11.1 2.6 5.7 0.5 6.9 9.2 0.9 1.3 8.2 8.3 1.7 5.2 4.1 0.1 2.8 4.1 27.2 30.1 23.5 26.9 22.7 31.2 38.4 41.0 28.2 28.7 42.7 20.1 102.6 9.6 1.1 1255.9 9.6 5.4 55.6 4.6 8.0 15.2 7.7 4.1 6.9 21.5 4.6 0.0 2.1 7.9 84.0 5.8 21.5 43.3 0.2 13.7 5.7 59.8 6.0 4.0 88.4 49.1 13.6 18.9 8.2 30.9 5.1 7.7 21.4 10.1 13.8 74.0 330.9 1.3 4.1 21.4 22.3 1.4 5.0 17.7 10.6 103.0 20.2 34.6 84.5 281.5 9.7 38.7 4.4 14.7 28.0 32.9 0.1 21.2 3.4 21.8 26.3 66.5 25.7 0.4 3.8 9.0 4.3 3.4 75.7 2.7 3.8 54.3 PKD2 "Pc-2, PC2, PKD4, TRPP2" ENSG00000118762 "Polycystin 2, transient receptor potential cation channel" Q13563 4 88007635-88077777 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Potassium transport, Transport, Wnt signaling pathway" "Calcium channel, Ion channel, Potassium channel, Voltage-gated channel" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.1;Inhibitory neurons: 148.6;Microglial cells: 95.5;Oligodendrocyte precursor cells: 178.9;Oligodendrocytes: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 137.2;BJ hTERT+: 207.1;fHDF/TERT166: 166.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004544, HPA015794, HPA055297" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" Cytosol "CAB004544: AB_672377, HPA015794: AB_1855437, HPA055297: " "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (1.22e-1)" "unprognostic (6.83e-2)" "unprognostic (9.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.17e-2)" "unprognostic (1.88e-1)" "unprognostic (8.64e-2)" "unprognostic (1.08e-1)" "unprognostic (6.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.17e-3)" "unprognostic (3.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.12e-2)" "unprognostic (2.51e-1)" 30.7 24.2 9.6 13.9 12.2 10.7 18.6 10.0 12.0 40.0 7.3 32.5 10.7 61.1 14.7 12.7 39.3 26.9 19.7 9.0 8.9 48.6 15.0 22.2 11.5 10.4 11.2 47.7 14.8 27.9 9.0 24.5 10.0 23.3 13.2 14.0 9.7 39.2 5.8 10.3 14.8 53.7 9.1 10.9 20.0 10.3 11.9 7.6 16.4 11.7 8.7 20.6 18.4 14.6 7.4 40.8 44.9 23.2 101.8 67.6 13.3 137.2 207.1 62.9 62.2 2.0 12.8 4.0 29.3 166.4 24.0 9.1 8.1 20.4 54.5 21.2 7.1 6.6 21.8 4.3 56.5 16.2 12.9 56.4 9.1 49.4 26.4 85.6 28.8 7.6 0.9 10.9 55.5 14.4 11.4 7.7 23.4 5.3 6.7 21.5 26.8 6.0 55.6 17.2 9.0 20.1 25.5 1.2 32.5 45.0 9.7 12.1 44.7 59.1 12.9 16.8 18.8 8.7 2.9 4.4 35.2 2.5 55.3 1.4 0.1 0.2 0.2 0.2 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.2 0.3 0.1 0.4 0.1 0.1 9.6 12.2 10.0 12.0 9.0 8.9 10.4 11.2 10.0 9.1 11.9 14.6 14.8 3.2 6.3 59.4 3.5 7.4 5.3 7.4 23.3 16.7 7.4 11.3 7.1 18.6 7.2 69.9 10.4 10.4 2.7 0.6 0.0 14.0 0.3 10.3 41.7 19.2 6.7 13.5 129.1 3.8 3.4 42.0 2.0 11.1 1.3 12.7 21.4 10.6 12.2 26.9 148.6 3.4 4.1 5.0 6.8 1.1 23.0 9.8 23.2 95.5 9.5 17.3 4.1 178.9 219.4 2.2 4.6 50.8 3.1 6.5 3.9 17.0 12.3 1.9 26.3 53.0 31.5 0.8 3.8 13.3 6.7 2.7 6.1 11.5 2.8 3.4 PKIA PRKACN1 ENSG00000171033 "CAMP-dependent protein kinase inhibitor alpha" P61925 8 78516340-78605267 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 1160.4;tongue: 953.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.8;Cardiomyocytes: 367.0;Excitatory neurons: 103.3;Inhibitory neurons: 78.2;Muller glia cells: 82.8;Oligodendrocyte precursor cells: 82.9" "Cancer enhanced" "Detected in many" "glioma: 15.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 21.4" "Lineage enriched" "Detected in many" 9 "T-cells: 21.4" "Cell line enhanced" "Detected in many" "HDLM-2: 63.9;HUVEC TERT2: 104.0;RT4: 100.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042791 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA042791: AB_10795761" "unprognostic (3.83e-3)" "unprognostic (1.89e-1)" "unprognostic (1.55e-2)" "unprognostic (5.59e-6)" "unprognostic (8.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.10e-3)" "unprognostic (1.65e-3)" "unprognostic (3.25e-2)" "unprognostic (2.58e-1)" "unprognostic (4.12e-1)" "unprognostic (1.00e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (5.41e-4)" "unprognostic (3.14e-1)" "unprognostic (1.38e-1)" "unprognostic (7.52e-3)" 2.5 9.5 44.4 5.6 49.3 2.7 4.1 41.4 49.2 2.2 11.9 3.5 1.2 3.1 3.0 21.5 5.3 8.2 185.9 49.8 44.0 4.7 0.2 8.6 7.6 25.4 34.3 5.8 1.4 108.1 8.0 1.6 36.0 20.3 2.8 33.7 6.2 5.3 1160.4 9.2 2.5 2.6 35.2 4.1 1.6 1.3 48.1 26.3 34.2 953.8 11.0 9.5 3.6 36.2 0.6 0.3 34.2 0.0 18.5 4.8 0.2 32.1 6.3 3.4 7.2 0.0 5.3 14.8 0.2 4.8 3.3 0.5 11.3 10.3 22.3 63.9 24.6 18.5 3.7 0.2 1.2 0.0 10.3 7.7 1.5 0.0 9.6 45.5 104.0 19.8 0.0 15.8 51.4 5.4 28.3 0.0 8.1 0.0 35.3 0.0 29.3 0.0 18.7 100.2 16.6 32.5 4.1 26.4 0.0 8.9 0.0 0.1 41.2 7.8 6.4 1.8 19.2 6.5 6.9 4.9 36.9 0.1 9.8 0.0 0.0 0.0 0.5 0.1 0.4 2.3 9.1 1.8 0.1 2.2 7.7 4.6 0.4 1.7 0.1 0.2 21.4 2.5 44.4 49.3 41.4 49.2 49.8 44.0 25.4 34.3 36.0 35.2 48.1 36.2 0.6 3.2 2.8 104.8 9.8 5.9 8.8 4.5 19.9 40.2 2.6 6.5 367.0 0.0 2.0 1.8 2.1 3.1 2.7 0.4 1.9 0.0 13.9 0.9 0.2 9.1 10.2 4.2 103.3 0.2 2.8 12.3 0.0 1.3 5.7 18.6 2.5 0.0 0.7 58.9 78.2 0.8 6.1 0.0 1.1 5.9 0.0 3.9 3.6 15.0 0.5 82.8 0.0 82.9 17.9 1.5 0.1 0.4 2.3 6.1 0.0 0.1 1.0 6.9 0.0 22.9 4.8 0.4 0.6 13.9 13.8 3.4 8.0 0.1 0.3 3.6 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980479 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.6;testis: 56.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.0;Extravillous trophoblasts: 52.0;Plasma cells: 22.9;Spermatocytes: 114.7;Spermatogonia: 46.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "T-reg: 1.3" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 1.1 1.0 0.4 6.8 0.5 27.6 0.6 1.6 1.4 2.2 0.2 3.9 2.8 0.6 0.3 11.5 0.4 0.6 0.9 0.5 0.2 0.9 1.6 2.0 8.0 0.7 0.6 0.3 1.8 0.1 1.0 3.1 0.8 1.0 1.3 17.4 1.9 0.1 2.4 4.4 4.0 1.0 0.5 5.6 3.3 56.9 0.7 9.6 0.5 0.0 4.5 0.7 3.3 0.8 84.2 57.0 22.0 31.2 0.3 0.9 64.0 65.5 15.1 40.0 38.4 45.0 49.3 54.2 29.2 7.9 24.2 106.7 15.7 20.7 7.2 71.7 56.7 27.9 52.7 40.0 0.0 31.2 73.6 0.7 1.8 24.0 6.5 5.0 8.4 57.6 80.6 87.0 13.5 127.5 83.6 88.0 37.9 39.3 34.4 93.7 51.2 100.7 7.8 17.7 42.6 46.7 31.9 77.7 23.9 12.1 44.7 56.9 7.7 53.2 69.7 77.3 68.0 67.6 54.2 94.0 19.4 40.0 61.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.3 0.4 0.5 1.6 1.4 0.5 0.2 0.7 0.6 0.8 0.5 0.7 0.8 0.0 0.0 1.1 0.0 1.9 2.5 1.3 2.1 0.6 0.4 1.5 1.3 0.6 1.5 1.6 1.8 6.2 16.0 1.3 5.0 0.0 0.8 20.0 0.6 0.8 0.8 1.8 29.0 0.4 0.6 52.0 2.5 3.1 1.9 0.0 4.5 0.0 0.4 11.8 0.0 0.2 3.6 6.1 2.1 1.8 8.6 0.3 1.9 0.0 0.0 0.7 0.2 0.0 0.0 0.3 0.6 0.3 0.4 22.9 0.7 0.3 0.1 0.2 7.1 0.0 0.1 2.6 114.7 46.1 11.2 0.6 7.4 4.2 0.5 8.6 2.0 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702503-128720916 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.1;Breast glandular cells: 15.3;Endothelial cells: 17.9;Microglial cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 78.0;REH: 42.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045390, HPA058305" Uncertain Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA045390: AB_2679308, HPA058305: AB_2683674" "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 12.6 2.7 6.1 2.6 5.8 2.6 13.2 7.3 6.8 6.3 4.7 5.1 4.7 7.6 0.6 5.2 7.0 2.3 15.9 5.0 5.2 9.0 4.1 11.1 2.1 6.1 5.9 2.8 5.3 2.2 1.8 3.3 6.0 5.4 0.9 0.1 11.5 2.0 3.6 5.4 6.2 2.8 5.4 9.5 7.0 2.6 7.2 2.8 6.9 3.4 1.1 6.9 6.3 5.3 2.9 14.1 11.3 17.2 0.1 0.3 27.7 8.7 2.7 12.6 13.0 0.1 10.1 0.1 8.4 4.7 2.6 19.0 13.8 2.1 2.9 9.0 26.0 17.1 78.0 20.5 2.1 2.1 3.0 0.6 0.7 6.8 1.9 2.7 25.1 5.0 39.6 1.9 2.3 26.9 2.6 9.2 10.5 13.1 4.1 42.4 21.3 3.8 5.3 1.7 1.9 8.5 6.6 3.5 6.5 6.1 12.3 13.6 21.9 0.1 10.3 20.0 6.7 6.2 2.9 5.7 1.6 2.2 8.0 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 6.1 5.8 7.3 6.8 5.0 5.2 6.1 5.9 6.0 5.4 7.2 5.3 27.1 0.0 2.0 0.3 1.2 1.0 1.7 1.7 3.4 0.2 15.3 3.6 1.8 4.3 2.1 0.0 0.0 2.2 2.0 1.5 0.0 1.9 0.2 2.2 1.1 17.9 0.0 5.0 0.3 2.6 6.1 1.8 5.1 4.9 0.0 5.0 9.3 0.4 1.9 0.0 0.2 1.7 0.0 0.8 2.3 0.9 1.5 0.8 0.0 13.1 1.2 0.3 4.1 0.0 0.1 3.3 1.5 0.7 1.6 1.1 2.6 0.6 0.5 0.2 0.0 0.7 1.3 2.8 6.6 2.8 1.0 1.4 1.9 1.4 2.5 1.7 PLA2G2E ENSG00000188784 "Phospholipase A2 group IIE" Q9NZK7 1 19920009-19923617 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "lymphoid tissue: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064085 Uncertain "Secreted - unknown location" NA NA "Cluster 16: Immune cells - Immune response" "HPA064085: AB_2685188" "unprognostic (9.56e-2)" "unprognostic (3.71e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828949-186988981 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 87.2;seminal vesicle: 48.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.4;Glandular and luminal cells: 28.1;Microglial cells: 115.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 6.8;eosinophil: 7.8;intermediate monocyte: 8.4;myeloid DC: 7.7;non-classical monocyte: 4.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 7 "dendritic cells: 7.7;granulocytes: 7.8;monocytes: 8.4" "Cell line enhanced" "Detected in many" "HeLa: 52.4;OE19: 84.4;RPMI-8226: 73.4;U-2197: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 35000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Cytosol Vesicles "CAB010050: AB_631312, HPA050062: AB_2681002, HPA054206: AB_2682417" "prognostic favorable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" 9.9 12.7 2.4 6.3 3.4 4.8 6.5 2.8 3.7 14.5 3.2 11.9 11.1 10.2 11.7 7.5 24.9 6.2 6.3 2.4 3.3 10.8 2.1 5.9 5.3 4.4 3.5 6.4 7.6 87.2 2.0 5.8 4.0 8.8 8.1 0.8 6.3 48.3 0.5 9.5 8.2 10.5 4.1 6.6 5.3 2.8 3.1 1.5 2.6 2.1 2.9 29.1 8.4 3.9 0.0 39.7 0.2 0.0 23.8 9.5 0.0 1.5 15.1 1.8 3.2 0.3 15.5 0.0 0.0 0.0 6.8 2.8 24.6 7.4 0.8 12.5 0.6 7.6 52.4 0.0 14.7 11.1 3.8 5.4 5.0 19.5 4.0 2.4 16.5 3.4 16.7 5.9 0.0 0.0 0.0 0.0 2.1 84.4 5.1 0.0 0.0 73.4 0.1 5.4 0.2 0.0 5.9 2.0 7.3 0.7 0.8 15.0 3.3 14.3 1.9 66.3 3.2 2.3 0.0 0.0 5.3 32.4 20.7 0.2 6.8 7.8 0.0 8.4 0.2 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.6 1.1 4.0 3.1 0.0 1.7 2.4 3.4 2.8 3.7 2.4 3.3 4.4 3.5 4.0 4.1 3.1 3.9 0.6 0.0 1.1 0.3 0.2 21.4 4.3 4.6 10.2 0.2 2.9 2.9 2.3 0.0 4.9 0.0 0.0 0.1 3.2 1.6 1.9 2.1 0.9 33.4 1.7 6.6 1.2 3.0 8.1 0.0 0.1 11.2 7.1 28.1 10.8 3.3 1.1 0.2 6.6 0.0 5.8 2.6 2.0 7.9 8.3 1.3 10.5 11.5 5.4 115.2 3.7 0.0 1.0 2.0 0.4 1.7 7.3 14.7 0.0 2.3 2.0 0.3 2.3 0.5 0.0 1.2 5.0 0.6 0.3 5.2 8.9 0.0 1.0 1.2 4.8 13.4 PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981582-42051190 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 17.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 12.9;Basal keratinocytes: 18.1;Suprabasal keratinocytes: 44.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041105, HPA072562" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Cytosol" "HPA041105: AB_2677300, HPA072562: " "unprognostic (2.98e-1)" "unprognostic (5.52e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.22e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-7)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (4.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 18.1 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 5.1 0.5 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 5.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 44.9 0.0 0.1 0.0 0.2 0.7 PLA2G4F PLA2G4F/Z ENSG00000168907 "Phospholipase A2 group IVF" Q68DD2 15 42139034-42156636 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 78.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 74.5;Distal enterocytes: 21.7;Gastric mucus-secreting cells: 18.3;Glandular and luminal cells: 17.1;Suprabasal keratinocytes: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "OE19: 11.1;RT4: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042713, HPA056752" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" Vesicles Nucleoplasm "HPA042713: AB_10793982, HPA056752: AB_2683226" "unprognostic (1.99e-1)" "unprognostic (6.21e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.06e-2)" "unprognostic (2.32e-3)" "unprognostic (1.48e-2)" "unprognostic (5.85e-2)" "unprognostic (2.25e-1)" "unprognostic (4.79e-2)" "unprognostic (6.65e-2)" "unprognostic (1.21e-2)" "unprognostic (9.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" "unprognostic (1.63e-1)" 0.0 0.0 0.1 0.4 0.3 0.3 2.4 0.1 0.1 5.7 0.0 6.4 6.7 0.0 1.6 5.7 0.1 0.1 0.3 0.1 0.0 7.8 0.2 12.2 0.1 0.0 0.0 0.0 0.1 2.9 1.7 0.1 0.0 4.3 3.8 0.2 2.6 0.4 2.9 78.1 4.2 0.1 0.0 0.1 2.4 0.1 0.0 4.4 1.9 0.5 0.3 1.2 11.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 11.1 0.1 0.0 0.0 0.0 0.0 8.3 0.4 0.0 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 74.5 0.0 0.0 5.5 2.7 1.3 0.6 0.0 1.2 0.3 2.9 0.0 0.5 5.5 0.0 1.7 0.0 21.7 3.9 0.4 0.0 7.3 1.0 0.1 0.0 0.0 0.0 1.3 0.7 0.1 18.3 17.1 2.5 0.0 0.0 0.0 0.1 0.0 0.0 7.7 4.1 0.0 0.3 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.3 0.0 0.3 3.1 10.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 5.6 13.8 1.2 0.6 0.0 6.7 2.0 PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.2;placenta: 23.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 372.2;Macrophages: 140.9" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 43.4" "Group enriched" "Detected in many" 49 "dendritic cells: 14.1;monocytes: 43.4" "Cell line enhanced" "Detected in some" "NTERA-2: 1.7;PC-3: 3.4;RT4: 1.6;U-2 OS: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 7380000 290000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" 4.5 3.1 1.6 22.9 3.6 2.8 2.6 2.7 4.5 2.5 0.4 7.5 4.1 4.8 1.1 0.6 1.9 6.0 0.6 2.6 1.4 0.3 6.9 7.2 26.8 3.9 2.6 1.1 0.8 21.0 2.1 23.3 4.2 13.1 10.3 0.6 1.4 2.6 0.4 3.6 3.3 2.8 2.6 27.2 2.9 0.9 8.9 4.9 20.2 0.0 10.0 11.1 0.3 7.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.7 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 3.4 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.3 43.4 0.3 0.1 9.2 0.3 0.3 0.0 0.0 14.1 0.0 0.0 0.1 0.5 0.0 0.5 0.3 0.0 11.9 1.6 3.6 2.7 4.5 2.6 1.4 3.9 2.6 4.2 2.6 8.9 7.4 0.5 0.0 1.3 0.3 3.6 0.8 4.4 0.0 0.0 0.2 0.3 4.3 0.3 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.6 0.1 1.6 50.3 0.6 3.5 0.0 7.1 0.0 5.1 1.8 0.0 1.5 0.0 0.0 0.0 0.0 372.2 1.7 4.8 0.3 0.0 24.6 4.9 0.1 0.0 140.9 10.6 11.2 29.3 0.3 0.0 6.0 0.3 0.3 0.0 0.0 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.9 0.6 0.1 0.0 0.1 0.1 3.1 0.8 8.9 0.2 3.8 PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 39.1;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Excitatory neurons: 34.6;Inhibitory neurons: 43.5;Muller glia cells: 33.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 14.5;ASC TERT1: 19.5;BJ hTERT+: 16.2;hTERT-RPE1: 26.3;TIME: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" NA NA 960000 "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" 4.7 2.9 0.7 1.4 0.8 0.0 14.9 9.7 2.2 6.9 1.7 3.1 3.9 8.8 2.9 4.7 5.4 9.3 2.5 0.5 1.5 20.8 1.4 2.6 1.9 2.0 2.7 10.8 0.6 19.7 2.2 3.8 2.1 3.1 3.2 5.6 39.1 2.9 0.5 10.9 6.1 6.9 1.4 5.1 1.6 1.0 2.5 0.6 41.9 1.3 2.7 3.9 6.0 1.0 0.2 1.6 0.6 0.0 14.5 19.5 0.1 6.8 16.2 1.3 1.8 0.0 3.4 0.0 0.4 7.2 1.4 3.3 0.1 5.0 1.4 0.0 0.0 0.0 11.8 0.0 1.2 0.0 0.0 7.9 5.4 1.9 2.1 26.3 9.3 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 1.4 0.7 0.0 0.0 11.8 2.2 0.0 1.7 2.6 0.2 47.3 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.8 9.7 2.2 0.5 1.5 2.0 2.7 2.1 1.4 2.5 1.0 11.1 6.4 2.8 20.9 0.1 9.4 2.7 18.1 21.6 2.7 22.1 14.5 4.1 5.7 11.3 33.1 0.0 7.3 0.5 1.7 0.0 0.6 0.1 5.6 22.0 4.0 1.2 0.0 34.6 2.0 1.3 14.8 0.0 9.4 1.3 9.6 8.6 0.0 0.6 16.8 43.5 7.2 4.1 0.0 2.1 1.4 16.1 0.5 7.2 25.3 0.0 33.5 0.0 5.5 1.8 5.1 11.3 16.6 0.1 2.6 15.6 2.3 8.1 1.4 6.6 3.4 4.8 0.1 1.0 9.3 5.4 1.5 0.6 6.3 7.5 3.0 PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 187.7;Hofbauer cells: 105.6;Kupffer cells: 109.4;Macrophages: 116.3;monocytes: 192.8;Paneth cells: 105.9" "Cancer enhanced" "Detected in all" "testis cancer: 113.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 662.9;intermediate monocyte: 204.4;myeloid DC: 357.3;neutrophil: 443.8" "Group enriched" "Detected in all" 135 "dendritic cells: 357.3;granulocytes: 443.8;monocytes: 662.9" "Cell line enhanced" "Detected in many" "AN3-CA: 48.6;BEWO: 98.4;CAPAN-2: 245.6;MCF7: 46.3" "Not detected" "Not detected" HPA040303 Enhanced "Intracellular and membrane" NA NA 3400000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA040303: AB_2676922" "unprognostic (9.13e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-1)" "unprognostic (7.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (4.80e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.12e-1)" "unprognostic (3.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (4.99e-2)" "unprognostic (5.44e-2)" 29.4 5.6 2.1 33.7 2.5 285.9 27.8 2.4 3.7 22.4 25.9 58.8 28.2 13.5 10.6 56.3 16.6 33.1 32.6 2.1 2.4 26.3 10.6 64.0 9.2 3.5 3.2 4.4 30.0 3.2 3.4 35.9 3.2 10.2 79.2 0.8 11.9 15.3 9.9 24.8 42.6 28.1 3.1 25.2 36.6 10.0 2.8 7.8 6.1 17.2 32.7 58.5 29.6 4.8 7.1 5.0 0.5 48.6 0.3 0.0 98.4 0.2 0.0 3.0 2.4 14.1 245.6 0.0 1.4 1.0 0.4 9.4 0.0 0.0 0.5 0.0 0.1 0.0 6.4 0.0 3.8 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.1 46.3 0.1 0.2 16.5 0.7 0.3 0.1 0.1 0.5 0.7 28.9 0.0 0.4 30.2 14.8 1.9 26.5 9.0 9.6 0.0 0.5 0.4 0.0 0.6 8.7 23.7 0.2 0.0 0.1 0.4 0.4 662.9 5.8 1.0 204.4 0.6 3.6 0.5 0.4 357.3 0.8 0.7 0.7 443.8 1.7 73.5 4.1 0.9 423.2 2.1 2.5 2.4 3.7 2.1 2.4 3.5 3.2 3.2 3.1 2.8 4.8 15.5 9.6 8.6 0.3 2.9 6.8 8.8 4.9 6.8 0.0 11.9 6.6 16.5 30.0 20.4 33.1 0.0 94.5 1.5 67.8 11.7 13.1 51.8 2.5 9.1 7.2 9.1 1.7 1.6 46.5 187.7 59.6 13.3 0.9 5.1 5.9 4.6 2.9 105.6 0.0 0.9 31.3 6.1 109.4 68.6 5.8 26.1 116.3 5.4 7.5 192.8 1.6 1.0 1.5 0.2 28.6 105.9 27.8 3.6 3.8 52.8 15.7 19.0 0.2 0.0 12.0 10.4 17.4 12.0 17.8 19.9 70.3 1.6 6.1 75.2 30.1 PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108959-45133354 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 85.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 195.8;Paneth cells: 104.7;Urothelial cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA025711: AB_1855320, HPA053665: AB_2732580" "unprognostic (3.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" "unprognostic (4.14e-3)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.96e-1)" "unprognostic (9.53e-2)" "unprognostic (1.34e-3)" "unprognostic (6.21e-2)" "unprognostic (3.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "prognostic favorable (4.28e-4)" "unprognostic (3.34e-3)" 13.5 34.3 42.2 5.1 49.7 2.0 11.7 50.5 36.0 12.4 27.9 34.2 2.5 13.2 1.5 14.7 10.1 6.4 34.1 33.8 42.5 9.6 1.4 7.7 1.0 69.8 50.5 18.9 2.7 1.3 7.6 5.8 46.4 13.0 15.3 14.4 10.8 5.4 85.7 20.6 6.5 5.1 62.8 2.0 21.0 10.8 59.4 0.9 5.3 56.5 1.5 30.4 11.9 54.0 23.1 56.2 4.1 8.1 5.9 12.8 28.0 12.3 27.3 11.2 10.5 13.7 40.9 0.8 43.5 29.0 9.2 51.9 6.3 53.1 4.4 11.6 21.0 0.9 62.6 18.1 30.3 1.3 3.2 13.7 21.0 10.4 13.7 28.5 7.0 2.5 5.0 1.7 12.1 36.2 3.7 5.4 4.9 109.9 55.0 8.1 9.2 1.5 35.8 45.1 1.1 7.2 13.3 22.1 12.5 8.5 47.0 2.5 14.3 6.9 37.9 9.3 14.8 2.1 2.6 1.8 11.4 1.5 5.7 0.7 0.3 0.5 0.1 0.3 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.2 0.0 0.1 0.1 0.1 42.2 49.7 50.5 36.0 33.8 42.5 69.8 50.5 46.4 62.8 59.4 54.0 8.7 12.8 1.3 22.9 1.0 7.6 16.3 12.2 21.1 29.8 6.8 9.3 26.9 14.3 4.9 7.3 25.0 3.9 0.9 195.8 1.9 6.7 15.8 3.3 12.7 9.0 4.9 0.0 1.3 3.5 13.1 10.6 29.6 9.6 1.3 6.5 10.4 0.7 1.6 6.7 3.7 15.1 4.1 1.4 1.9 5.5 19.9 1.6 3.6 1.0 1.2 8.9 0.0 0.0 0.1 30.0 104.7 33.1 1.1 28.7 4.2 2.0 2.7 40.0 6.6 16.8 4.9 2.3 7.6 3.8 5.7 7.3 1.1 7.0 46.2 88.6 PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 93993931-94332823 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;Astrocytes: 69.5;Distal enterocytes: 79.6;Inhibitory neurons: 83.9;Muller glia cells: 82.7;Oligodendrocyte precursor cells: 123.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA015597: AB_1855321, HPA015598: AB_1855322" "unprognostic (4.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.59e-3)" "unprognostic (3.01e-1)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (4.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-3)" "unprognostic (3.56e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" "unprognostic (4.30e-2)" 3.8 2.6 4.5 2.8 4.1 0.2 2.7 3.1 5.6 8.0 7.0 12.6 4.0 9.0 5.3 1.7 4.4 2.5 12.4 3.9 4.7 8.4 0.7 7.3 0.7 3.9 4.8 3.9 14.7 0.8 4.4 2.9 4.0 3.8 7.5 7.3 2.3 5.4 4.1 1.1 5.2 4.2 3.2 6.2 8.3 2.0 5.4 0.5 9.8 6.3 0.6 5.6 5.6 4.2 4.0 6.7 1.8 1.1 0.7 3.2 1.9 2.8 0.6 0.3 0.4 5.3 1.3 0.8 1.3 2.3 1.3 2.6 2.2 0.4 0.6 0.4 2.3 0.5 4.0 0.5 0.0 0.9 0.3 1.8 0.0 1.1 0.0 6.8 0.0 0.4 0.5 0.3 4.2 0.3 0.8 0.9 0.7 7.9 5.0 0.1 3.9 0.2 0.2 10.3 0.9 1.5 3.3 3.6 0.7 4.1 3.5 0.6 0.6 3.0 5.9 2.0 4.4 0.6 0.3 0.4 3.5 1.1 2.2 0.1 0.1 0.0 0.3 0.2 0.2 0.5 0.3 0.2 0.1 0.7 0.5 0.4 0.1 0.2 0.2 0.2 0.1 0.1 4.5 4.1 3.1 5.6 3.9 4.7 3.9 4.8 4.0 3.2 5.4 4.2 8.2 70.5 5.4 69.5 7.0 8.2 9.7 6.8 2.2 12.2 3.6 3.6 34.7 4.3 12.3 0.0 0.0 3.7 2.9 79.6 1.9 1.1 20.7 26.7 18.4 9.7 1.8 0.0 3.1 6.4 2.5 15.3 29.6 10.6 0.0 7.2 4.2 1.6 0.7 6.7 83.9 9.7 4.1 2.4 5.2 5.3 12.2 1.3 7.2 5.6 1.2 82.7 4.1 123.1 2.4 4.2 54.8 23.3 0.9 7.5 11.0 2.5 10.6 18.7 6.6 30.8 37.7 3.7 8.0 1.7 7.4 1.9 4.3 3.7 41.1 10.5 PLCXD3 ENSG00000182836 "Phosphatidylinositol specific phospholipase C X domain containing 3" Q63HM9 5 41306952-41510628 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;heart muscle: 33.2;ovary: 22.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 138.2;Endometrial stromal cells: 58.7;Enteroendocrine cells: 42.4;Inhibitory neurons: 163.5;Microglial cells: 52.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 8.5;PC-3: 7.5;SH-SY5Y: 34.3;TIME: 18.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046849 Uncertain Approved "Golgi apparatus" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA046849: AB_2679838" "unprognostic (1.71e-1)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (7.04e-3)" "unprognostic (1.43e-1)" "unprognostic (2.44e-1)" "unprognostic (4.90e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-2)" "unprognostic (3.12e-1)" "unprognostic (6.38e-3)" "unprognostic (2.57e-1)" "unprognostic (2.73e-2)" "unprognostic (2.15e-3)" "unprognostic (5.91e-5)" "unprognostic (5.11e-2)" "unprognostic (6.75e-2)" 3.9 12.7 4.5 0.5 4.1 0.0 2.4 17.8 4.2 2.9 1.1 0.9 0.5 1.1 0.9 0.6 3.4 2.4 33.2 3.4 9.5 5.9 1.6 1.8 1.6 8.2 10.4 22.5 3.6 0.3 5.3 0.1 16.0 1.0 0.6 0.7 0.4 1.0 0.5 0.7 1.2 1.2 7.7 0.2 5.0 0.4 12.1 0.5 1.5 0.7 0.2 1.4 4.0 6.3 0.0 3.7 0.0 0.0 0.0 0.0 0.0 1.8 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.4 34.3 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 4.1 17.8 4.2 3.4 9.5 8.2 10.4 16.0 7.7 12.1 6.3 8.7 0.0 0.0 7.5 0.1 0.1 0.1 0.0 0.0 0.7 0.1 0.0 138.2 5.7 0.0 0.0 0.0 0.1 0.0 0.1 3.9 0.3 0.9 1.7 58.7 13.6 42.4 5.3 27.8 0.0 2.0 10.3 0.0 1.1 0.0 33.4 33.2 0.4 0.1 1.7 163.5 2.2 0.0 0.6 0.3 4.4 7.8 0.2 0.0 52.5 0.0 0.4 0.0 7.5 1.3 0.9 0.0 0.4 0.0 0.3 0.1 10.4 0.0 0.2 6.6 0.2 2.9 0.2 0.0 0.2 0.0 0.1 0.3 9.7 0.1 0.1 PLD4 C14orf175 ENSG00000166428 "Phospholipase D family member 4" Q96BZ4 14 104924713-104937761 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.4;brain: 16.7;lymphoid tissue: 11.3" "Cell type enriched" "Detected in many" 7 "dendritic cells: 284.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 3621.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 3621.6" "Group enriched" "Detected in some" 4 "HMC-1: 127.3;RPMI-8226: 85.5;THP-1: 191.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051512 Uncertain NA NA 2900000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA051512: AB_2681515" "unprognostic (4.50e-3)" "unprognostic (1.78e-4)" "unprognostic (7.12e-2)" "unprognostic (5.30e-3)" "unprognostic (5.54e-2)" "unprognostic (2.91e-3)" "unprognostic (2.56e-1)" "unprognostic (4.76e-3)" "unprognostic (1.45e-3)" "unprognostic (1.19e-3)" "unprognostic (3.45e-3)" "unprognostic (3.89e-1)" "unprognostic (6.90e-3)" "unprognostic (8.94e-2)" "unprognostic (2.83e-1)" "unprognostic (1.28e-2)" "unprognostic (2.41e-1)" 0.4 1.0 5.1 5.7 4.7 13.4 1.5 7.0 7.1 1.0 0.4 0.8 3.8 1.0 0.2 0.6 1.8 2.4 0.5 4.5 7.3 0.8 0.5 1.8 11.3 15.7 6.8 0.5 1.1 1.2 2.1 0.8 10.3 1.7 0.5 0.5 3.5 1.8 0.3 0.6 5.1 0.5 13.9 10.4 2.8 0.6 9.4 2.8 0.6 0.0 9.4 1.9 0.4 16.7 0.1 0.2 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 9.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 127.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 10.7 0.1 0.0 0.1 30.0 0.1 85.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 191.5 0.0 0.1 0.3 0.1 0.2 0.4 0.0 0.1 0.2 1.6 0.3 4.6 43.0 699.5 1.0 188.4 1.9 222.7 0.8 1.2 545.8 198.4 1.7 0.4 9.8 25.4 297.9 3621.6 1.0 72.9 5.1 4.7 7.0 7.1 4.5 7.3 15.7 6.8 10.3 13.9 9.4 16.7 0.8 0.0 0.0 0.3 34.7 0.4 0.1 0.0 0.0 2.7 0.6 2.8 1.4 0.0 0.0 0.0 0.0 0.2 284.8 0.0 0.0 0.0 0.7 0.1 0.3 2.7 0.0 5.5 0.1 0.0 0.4 1.1 1.1 0.4 3.8 0.0 0.0 0.0 30.6 1.7 0.1 0.0 0.0 1.3 32.0 4.7 0.0 38.0 5.4 22.5 11.3 0.1 2.1 0.5 0.1 0.0 0.0 0.0 2.3 0.1 0.0 0.1 0.0 1.1 6.6 1.6 0.3 1.6 1.6 0.0 0.4 0.3 2.2 0.0 0.1 0.0 PLEKHA6 "KIAA0969, PEPP3" ENSG00000143850 "Pleckstrin homology domain containing A6" Q9Y2H5 1 204218853-204377665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 111.0;Distal enterocytes: 66.6;Excitatory neurons: 102.6;Inhibitory neurons: 62.5;Oligodendrocyte precursor cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 60.3;BEWO: 94.6;CAPAN-2: 79.2;OE19: 80.9;RT4: 66.4;SK-BR-3: 58.4;T-47d: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028152, HPA028157, HPA054311" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Vesicles "HPA028152: AB_10601048, HPA028157: , HPA054311: AB_2682446" "unprognostic (9.81e-3)" "unprognostic (3.05e-1)" "unprognostic (1.59e-2)" "unprognostic (3.14e-2)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (2.37e-2)" "unprognostic (1.38e-2)" "unprognostic (9.01e-2)" "unprognostic (3.32e-1)" "unprognostic (9.60e-3)" "unprognostic (1.53e-1)" "unprognostic (5.02e-3)" "unprognostic (1.23e-1)" "unprognostic (8.22e-2)" "unprognostic (5.17e-2)" "prognostic favorable (3.57e-4)" 5.1 6.6 20.4 6.0 21.6 0.4 13.7 20.9 34.4 4.1 9.1 32.2 25.5 4.8 12.9 17.2 9.3 13.2 20.8 19.6 18.7 27.4 27.5 3.2 0.6 23.1 24.3 4.6 10.2 5.7 31.1 8.8 23.3 13.8 29.3 11.4 9.0 13.9 6.0 4.0 29.5 3.8 17.9 3.1 39.7 5.4 34.6 1.0 4.0 2.4 2.4 12.7 7.5 24.1 60.3 36.8 23.7 0.1 0.3 0.6 94.6 2.1 6.6 0.2 0.3 17.8 79.2 0.3 17.3 1.4 0.3 6.7 0.3 6.5 0.3 0.2 3.8 0.2 15.2 25.7 3.5 0.0 0.1 1.0 19.6 0.0 5.0 7.2 10.4 0.8 0.1 0.2 23.9 26.7 0.1 0.1 7.4 80.9 44.6 0.0 0.2 0.1 23.0 66.4 4.8 48.4 26.6 58.4 0.4 4.9 55.3 0.3 0.7 0.0 1.0 0.3 0.5 0.2 0.0 0.1 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 21.6 20.9 34.4 19.6 18.7 23.1 24.3 23.3 17.9 34.6 24.1 0.2 0.0 10.9 111.0 0.3 0.1 4.2 1.9 0.6 41.6 15.7 8.1 16.6 37.1 4.5 9.2 20.9 6.6 0.5 66.6 3.9 8.4 10.4 4.0 1.3 1.2 16.8 2.7 102.6 5.1 2.4 9.0 40.8 6.2 0.0 0.3 5.0 21.4 0.8 18.5 62.5 32.7 4.1 0.6 0.7 4.0 5.3 0.7 0.0 15.0 0.1 1.2 0.0 85.5 41.8 13.3 33.2 3.8 0.1 6.9 15.2 11.7 7.2 7.1 0.0 26.4 1.1 0.6 0.2 1.4 0.6 21.6 0.6 0.1 34.5 13.7 PLEKHF1 "APPD, MGC4090, PHAFIN1, ZFYVE15" ENSG00000166289 "Pleckstrin homology and FYVE domain containing 1" Q96S99 19 29665459-29675477 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 77.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 59.2;Leydig cells: 78.3;NK-cells: 166.9;Peritubular cells: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 13 "NK-cells: 82.3;T-cells: 183.9" "Cell line enhanced" "Detected in many" "BEWO: 39.0;SK-BR-3: 32.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA025925 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA025925: AB_1844958" "unprognostic (5.01e-2)" "unprognostic (6.39e-2)" "unprognostic (1.31e-2)" "unprognostic (3.04e-2)" "unprognostic (9.43e-3)" "unprognostic (2.57e-1)" "unprognostic (4.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-3)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.54e-5)" "unprognostic (1.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-2)" "prognostic favorable (4.54e-4)" 18.0 3.6 9.4 4.6 12.4 6.7 17.0 10.8 9.7 18.1 5.9 9.9 4.0 18.8 1.9 15.3 15.5 4.6 24.8 7.8 10.1 4.9 16.4 10.5 9.0 14.2 12.5 8.4 4.9 5.9 2.5 4.9 11.3 16.5 1.1 0.2 18.6 6.1 77.3 8.5 10.0 2.7 10.8 14.4 7.2 3.4 13.9 7.4 6.3 38.5 5.1 16.9 14.9 14.0 14.3 5.2 0.1 3.3 10.5 9.0 39.0 3.6 4.9 4.4 7.1 3.3 6.4 0.1 12.7 4.7 8.1 12.6 1.1 3.3 0.7 9.7 7.1 7.1 2.6 6.5 17.9 0.4 19.0 15.8 1.3 4.7 8.7 2.8 3.8 7.1 8.2 0.0 2.5 1.9 1.0 5.9 0.7 2.3 2.5 0.1 4.7 4.0 3.0 22.5 0.1 2.3 2.0 32.9 18.4 3.2 12.0 2.1 3.5 5.7 5.9 7.2 6.7 2.5 27.3 1.2 6.3 7.5 2.0 10.4 0.8 0.2 183.9 0.5 128.1 5.5 74.0 147.2 1.4 10.2 43.9 82.4 2.1 82.3 0.9 0.6 76.4 67.1 9.4 12.4 10.8 9.7 7.8 10.1 14.2 12.5 11.3 10.8 13.9 14.0 5.2 0.0 0.5 1.3 9.5 55.2 29.0 15.8 17.1 0.8 12.7 9.0 8.7 18.6 9.6 9.2 0.0 59.2 53.6 0.9 5.9 22.1 0.5 4.4 10.1 11.2 0.0 2.7 0.2 8.3 7.4 17.6 2.0 7.8 0.0 0.8 12.5 10.0 11.1 0.0 0.4 1.2 16.2 3.0 12.6 1.9 78.3 3.0 17.8 9.4 0.5 5.5 166.9 0.0 5.6 3.8 2.5 72.6 10.1 34.0 0.5 6.0 4.2 0.5 0.0 24.7 7.6 0.4 1.8 8.9 35.8 38.4 40.9 0.9 1.2 25.4 PLEKHF2 "FLJ13187, PHAFIN2, ZFYVE18" ENSG00000175895 "Pleckstrin homology and FYVE domain containing 2" Q9H8W4 8 95133785-95156685 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 102.6;U-698: 109.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024829 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA024829: AB_10603127" "unprognostic (4.08e-2)" "unprognostic (2.98e-2)" "unprognostic (5.72e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.67e-2)" "unprognostic (4.83e-2)" "unprognostic (1.19e-1)" "unprognostic (2.67e-1)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (5.94e-2)" "prognostic favorable (1.49e-4)" "unprognostic (2.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (4.61e-3)" 12.4 6.1 5.5 21.3 5.5 84.8 21.6 6.1 6.7 9.2 6.9 16.0 12.6 7.4 14.6 15.4 8.9 11.2 8.9 5.2 5.7 22.2 14.7 17.5 53.1 6.3 5.8 7.3 11.8 6.9 3.6 15.1 6.2 9.3 13.9 14.8 11.8 7.4 10.7 19.5 13.7 7.1 6.6 22.6 21.9 12.3 5.4 23.8 9.7 9.3 56.1 12.7 7.5 8.3 27.5 4.5 7.0 4.2 10.0 11.1 37.6 14.9 20.0 12.7 13.6 11.3 29.7 102.6 12.6 10.5 6.6 33.1 10.9 18.1 18.3 19.2 7.4 49.4 10.0 8.8 9.9 9.9 68.7 7.1 25.0 10.0 18.8 14.9 14.1 32.9 32.6 13.0 13.6 16.8 29.0 12.8 4.2 50.1 20.6 11.5 7.1 14.0 10.4 24.2 9.3 5.4 11.3 13.5 27.8 9.7 36.2 16.0 9.0 9.8 6.7 8.6 8.7 17.2 14.9 109.4 7.5 22.8 14.1 107.2 21.6 43.0 9.0 18.6 10.8 69.7 11.2 13.9 24.3 78.6 12.9 12.7 29.8 12.4 16.0 10.1 13.7 19.4 5.5 5.5 6.1 6.7 5.2 5.7 6.3 5.8 6.2 6.6 5.4 8.3 29.3 12.8 14.1 7.2 88.8 61.4 73.4 29.7 56.3 17.0 49.0 22.7 7.0 31.5 26.1 5.5 14.6 51.6 17.8 46.7 29.4 13.6 59.5 47.1 12.0 18.5 33.6 34.5 5.0 22.0 36.1 11.9 31.1 59.5 60.4 14.4 25.0 11.0 29.6 6.7 2.4 14.6 57.0 22.6 54.0 19.8 8.7 34.7 21.4 14.0 31.9 19.1 13.4 10.6 4.7 14.6 39.0 3.8 21.3 42.4 20.7 95.9 26.2 31.7 13.1 10.8 14.5 55.2 16.0 47.2 57.7 50.9 27.4 6.0 17.7 75.4 PLEKHM1 KIAA0356 ENSG00000225190 "Pleckstrin homology and RUN domain containing M1" Q9Y4G2 17 45435900-45490749 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.5" "Cell line enhanced" "Detected in many" "OE19: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025018, HPA039473" Approved Supported Nucleoli,Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoli "HPA025018: AB_1855465, HPA039473: AB_2676526" "unprognostic (1.52e-1)" "unprognostic (3.13e-2)" "unprognostic (4.29e-2)" "prognostic favorable (1.28e-6)" "unprognostic (8.71e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.20e-2)" "unprognostic (1.88e-1)" "unprognostic (2.93e-2)" "unprognostic (4.02e-1)" "unprognostic (3.93e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" 7.0 6.4 2.9 5.5 2.9 9.7 6.2 3.5 3.8 12.9 3.2 6.5 3.5 5.7 1.0 31.7 5.9 5.3 6.2 2.8 3.1 3.6 3.6 8.8 4.8 3.7 3.1 4.9 6.1 4.4 5.7 2.9 3.2 5.1 3.6 1.6 14.4 0.9 12.3 11.8 6.2 2.0 2.8 6.8 5.6 3.4 3.4 5.4 6.5 7.2 4.8 6.8 13.6 3.7 7.3 11.0 1.7 5.4 8.4 4.8 0.1 3.3 4.9 1.9 2.6 4.2 6.0 5.2 3.4 3.9 14.1 1.7 4.1 1.9 1.6 13.7 3.5 0.0 5.6 6.9 2.0 0.0 4.3 2.2 4.9 0.9 8.0 3.8 10.0 0.0 5.2 6.2 9.1 6.0 5.2 1.1 1.7 26.6 9.0 2.8 5.6 5.3 6.0 16.8 3.2 2.1 3.2 4.5 5.2 4.8 10.1 5.3 19.1 12.7 3.6 5.2 5.9 0.6 6.2 1.8 7.7 2.8 5.8 2.8 1.2 1.0 0.2 0.3 0.0 1.2 0.6 0.2 0.3 0.3 0.2 0.0 6.5 0.7 0.4 0.2 0.5 0.2 2.9 2.9 3.5 3.8 2.8 3.1 3.7 3.1 3.2 2.8 3.4 3.7 12.6 12.8 18.1 7.8 17.5 18.0 18.1 10.3 6.8 10.4 11.7 8.4 8.7 15.7 12.7 12.9 16.7 4.8 24.3 25.6 5.9 8.1 4.3 24.9 11.1 12.1 13.8 10.8 13.5 8.2 4.7 12.1 19.9 27.9 1.3 5.4 12.8 8.1 9.1 16.8 13.3 13.0 4.1 27.9 15.2 2.0 7.2 21.1 7.2 9.4 13.7 7.3 14.4 7.5 20.8 18.3 17.7 7.9 22.9 27.2 8.6 10.5 11.9 8.2 0.0 17.7 7.6 7.6 3.7 10.0 16.3 8.6 18.5 9.3 12.2 43.1 PLEKHN1 DKFZP434H2010 ENSG00000187583 "Pleckstrin homology domain containing N1" Q494U1 1 966482-975865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.9;skin 1: 46.0;vagina: 24.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 29.6;Pancreatic endocrine cells: 38.5;Prostatic glandular cells: 37.9;Squamous epithelial cells: 19.2;Urothelial cells: 52.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 15.1;HaCaT: 26.0;SK-BR-3: 16.6" "Not detected" "Not detected" HPA031742 Uncertain Approved "Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA031742: AB_10670704" "unprognostic (2.72e-3)" "unprognostic (8.05e-3)" "unprognostic (9.03e-2)" "unprognostic (4.47e-2)" "unprognostic (7.50e-4)" "unprognostic (2.93e-2)" "unprognostic (1.38e-2)" "unprognostic (1.78e-1)" "unprognostic (3.24e-1)" "unprognostic (1.01e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (9.98e-2)" "unprognostic (1.96e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" 0.4 1.6 0.0 0.7 0.1 0.4 1.7 0.0 0.1 11.5 0.0 0.6 0.9 0.4 0.3 54.9 0.9 0.7 0.2 0.0 0.0 2.1 0.9 1.1 0.3 0.0 0.0 0.1 1.1 0.5 0.3 0.4 0.0 3.6 0.1 0.0 10.2 1.2 2.1 46.0 0.8 0.1 0.0 1.2 2.0 0.4 0.1 0.1 0.7 0.0 1.6 7.5 24.2 0.0 15.1 1.4 0.0 1.0 0.1 0.7 2.5 6.8 1.7 4.1 1.1 2.0 11.3 0.0 3.2 3.0 5.7 26.0 0.2 4.5 0.7 5.0 1.0 0.0 5.6 3.3 0.6 0.3 0.2 0.2 3.8 2.9 1.6 3.7 0.5 0.0 0.3 4.0 0.2 8.3 0.0 0.3 0.5 2.4 11.0 0.1 0.0 5.6 4.3 4.2 0.1 0.1 7.5 16.6 1.0 0.4 3.2 0.0 3.2 5.3 2.3 0.5 4.6 3.2 0.1 0.1 6.8 2.5 3.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.2 1.1 0.0 1.9 4.6 29.6 5.0 1.8 0.5 3.8 1.8 0.9 0.0 6.4 0.0 0.0 7.1 1.0 1.9 0.0 13.8 0.0 3.0 1.1 0.7 0.0 0.0 0.0 14.0 2.0 0.9 3.1 8.2 0.0 0.0 0.7 0.3 1.1 3.3 0.0 0.0 8.2 0.3 1.4 0.0 0.0 0.9 1.8 0.0 1.9 0.2 0.0 0.0 0.0 38.5 3.3 0.0 2.5 37.9 0.0 0.1 5.2 0.2 0.0 0.2 1.0 0.0 0.7 19.2 17.3 9.9 2.8 0.0 0.1 52.9 PLEKHS1 "bA211N11.2, C10orf81, FLJ23537" ENSG00000148735 "Pleckstrin homology domain containing S1" Q5SXH7 10 113751262-113783429 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 30.5;cervix: 63.6;intestine: 43.9;pancreas: 36.9;salivary gland: 57.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 35.1;Club cells: 70.7;Endometrial ciliated cells: 33.8;Exocrine glandular cells: 31.1;Ionocytes: 38.7;Proximal enterocytes: 42.1;Respiratory ciliated cells: 157.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 10.1;OE19: 53.5;RT4: 22.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA037583 Approved Vesicles,Centrosome NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Centrosome Vesicles "HPA037583: AB_10671762" "unprognostic (2.64e-1)" "unprognostic (1.64e-2)" "unprognostic (2.74e-2)" "unprognostic (3.60e-2)" "unprognostic (1.07e-1)" "unprognostic (2.63e-2)" "unprognostic (1.74e-2)" "unprognostic (2.36e-2)" "unprognostic (8.43e-2)" "unprognostic (6.82e-2)" "unprognostic (2.57e-1)" "unprognostic (1.21e-2)" "unprognostic (0.00e+0)" "unprognostic (4.00e-3)" "unprognostic (2.19e-1)" "unprognostic (2.27e-1)" "prognostic favorable (1.03e-4)" 0.3 0.1 0.0 7.3 0.0 0.3 30.5 0.0 0.3 63.6 0.0 3.6 43.9 1.8 3.9 1.0 9.4 2.7 0.4 0.0 0.0 0.9 0.1 6.7 0.2 0.2 0.0 0.1 36.9 0.1 0.2 0.1 0.0 6.0 4.7 0.4 57.0 3.3 0.0 0.8 38.7 0.5 0.0 0.2 8.8 0.9 0.0 0.1 0.1 0.0 2.8 1.5 0.0 0.1 0.2 1.4 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.1 0.7 0.2 10.1 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.0 53.5 0.0 0.2 6.4 0.3 1.7 22.3 0.1 0.2 0.1 1.4 0.0 0.0 6.3 0.0 0.0 0.2 0.2 0.2 0.5 4.7 0.2 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 3.2 3.2 0.3 0.0 0.1 0.3 35.1 0.0 0.0 16.6 8.3 0.4 0.0 70.7 0.0 0.0 0.0 0.1 6.7 0.0 4.9 13.2 33.8 0.3 0.5 0.0 0.0 0.2 31.1 0.0 0.6 3.1 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 5.6 38.7 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 1.2 2.8 0.4 0.0 1.4 42.1 0.3 157.3 0.0 0.0 0.3 3.7 0.2 0.1 0.6 0.0 0.0 0.3 0.0 12.1 0.5 PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880893-127899224 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 22.6;lymphoid tissue: 14.4;testis: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 65.9;Late spermatids: 87.5;Spermatocytes: 53.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centrosome, Cytosol" "HPA017327: AB_2669584, HPA035026: AB_10602080, HPA043198: AB_2732504" "unprognostic (2.44e-1)" "unprognostic (4.24e-2)" "prognostic favorable (7.46e-5)" "unprognostic (2.18e-1)" "unprognostic (3.79e-1)" "unprognostic (9.20e-2)" "unprognostic (1.06e-5)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.44e-3)" "unprognostic (5.66e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (1.27e-1)" "unprognostic (2.22e-11)" "unprognostic (2.29e-2)" "unprognostic (3.58e-1)" "unprognostic (4.75e-2)" "unprognostic (7.93e-2)" 1.0 1.1 0.4 4.9 0.5 22.6 2.0 0.2 0.7 0.9 0.1 3.5 2.8 1.5 0.6 3.2 1.3 1.1 0.5 0.5 0.6 0.6 0.8 0.9 7.4 0.5 0.5 1.0 0.4 0.6 0.2 3.6 0.4 0.9 4.3 2.1 0.9 0.9 0.1 2.3 2.9 1.8 0.4 1.6 2.0 22.6 0.6 14.4 0.9 0.7 7.3 1.3 1.4 0.4 26.1 12.1 44.3 22.9 1.5 4.2 20.1 24.9 17.6 32.4 33.3 17.0 26.1 34.9 9.0 13.9 26.3 16.7 31.6 19.9 49.6 27.4 13.1 31.6 20.0 16.0 0.5 45.2 35.9 1.4 2.0 29.7 13.6 5.9 25.3 26.3 37.5 45.2 27.6 18.2 69.9 20.1 20.7 26.3 13.6 36.0 30.9 12.1 10.8 16.4 24.4 20.0 15.8 14.2 7.6 18.7 11.5 19.3 11.0 25.3 24.4 17.4 31.4 23.1 27.4 49.0 13.0 33.7 28.7 0.0 0.1 0.4 0.4 0.2 0.3 0.1 0.5 0.5 0.2 0.2 0.1 0.6 0.0 0.4 0.1 0.1 1.2 0.2 0.4 0.5 0.2 0.7 0.5 0.6 0.5 0.5 0.4 0.4 0.6 0.4 1.6 0.0 0.6 0.0 1.6 1.7 0.9 1.7 1.2 1.8 1.0 0.9 0.9 0.0 0.6 1.8 0.0 6.0 1.9 2.0 0.0 0.6 65.9 4.7 1.0 1.0 2.4 19.6 0.8 0.4 12.9 1.6 4.1 2.0 1.3 7.5 0.4 0.5 3.7 0.0 0.8 3.3 6.1 1.3 0.6 87.5 2.8 1.5 0.0 1.0 1.2 1.1 1.0 1.0 1.2 0.1 0.5 0.4 8.7 0.7 0.5 0.6 3.7 0.8 0.0 0.4 3.6 53.5 13.4 6.8 0.9 3.8 2.1 0.8 4.5 1.7 PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 392.7;Hepatic stellate cells: 779.6;Leydig cells: 1092.6;Peritubular cells: 398.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cell line enhanced" "Detected in many" "ASC diff: 710.0;ASC TERT1: 351.8;HSkMC: 438.1;U-2197: 660.4" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" 168.4 53.0 93.9 33.6 94.2 13.1 139.8 87.3 105.9 294.6 50.7 56.7 24.0 107.2 56.2 51.3 122.5 66.3 84.6 88.3 90.6 91.4 182.0 87.0 22.4 107.5 108.1 81.9 36.8 130.2 23.1 225.5 87.7 102.8 41.8 19.0 76.2 169.7 50.9 82.1 45.8 65.6 86.8 23.3 66.0 37.3 113.2 29.8 327.6 63.0 19.9 139.2 142.8 88.6 3.3 10.8 14.1 1.5 710.0 351.8 34.5 39.3 39.7 35.5 17.4 31.8 6.2 5.2 4.6 59.3 39.4 5.9 2.1 0.8 7.4 0.0 9.4 1.3 4.4 44.5 17.3 0.1 0.0 438.1 3.0 34.2 28.6 25.1 34.1 0.4 2.9 0.1 39.0 3.2 0.1 0.5 43.3 9.2 42.6 0.1 0.1 1.7 6.1 32.6 0.4 28.1 12.4 16.1 4.2 42.6 5.2 0.0 21.6 176.2 14.4 660.4 1.8 0.0 0.0 0.0 31.0 1.7 12.7 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 93.9 94.2 87.3 105.9 88.3 90.6 107.5 108.1 87.7 86.8 113.2 88.6 148.5 25.6 18.9 0.0 7.2 0.0 19.8 0.0 35.3 3.9 12.2 31.2 0.0 44.3 13.0 22.0 0.0 127.0 1.1 8.1 21.5 21.5 7.9 13.9 139.4 148.3 2.4 8.0 0.0 9.2 9.8 392.7 5.6 16.3 3.8 8.1 779.6 132.6 38.8 0.0 0.0 8.5 0.0 35.2 0.0 28.3 1092.6 14.9 0.0 0.0 0.9 136.0 0.0 0.0 0.0 7.9 5.9 398.7 7.1 20.8 15.5 21.3 4.4 4.1 138.1 179.7 107.2 4.5 3.4 16.4 0.0 214.9 5.0 22.4 7.2 20.1 PLPPR1 "FLJ20300, LPPR1, MGC26189, PRG-3" ENSG00000148123 "Phospholipid phosphatase related 1" Q8TBJ4 9 101028727-101325135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;kidney: 15.6" "Group enriched" "Detected in some" 4 "Distal tubular cells: 37.2;Early spermatids: 12.3;Proximal tubular cells: 39.0" "Group enriched" "Detected in some" 5 "glioma: 11.1;liver cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Hep G2: 3.7;SCLC-21H: 9.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014760, HPA014968, HPA014979" Supported Supported Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA014760: AB_2669084, HPA014968: AB_1855702, HPA014979: AB_2669130" "unprognostic (1.08e-2)" "unprognostic (2.79e-1)" "unprognostic (2.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (7.33e-2)" "unprognostic (3.41e-1)" "prognostic favorable (1.37e-4)" "unprognostic (2.09e-1)" "unprognostic (1.14e-1)" "unprognostic (9.86e-4)" "unprognostic (1.44e-1)" "unprognostic (1.65e-6)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (2.85e-1)" "unprognostic (4.83e-2)" 0.0 0.1 9.7 0.0 12.8 0.0 0.7 7.1 12.7 0.1 5.2 0.2 0.0 0.0 2.8 0.0 0.2 0.0 0.0 10.4 9.3 15.6 3.6 1.4 0.0 10.2 9.1 0.0 0.3 0.0 0.1 0.0 9.8 0.2 0.1 1.5 0.3 0.0 0.0 0.1 0.0 0.0 9.6 0.0 0.1 0.6 10.9 0.4 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 9.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 12.8 7.1 12.7 10.4 9.3 10.2 9.1 9.8 9.6 10.9 11.5 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.3 2.3 0.0 1.5 0.6 0.0 0.0 0.0 0.1 0.0 37.2 0.0 12.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.0 39.0 0.0 1.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 PLS3 T-plastin ENSG00000102024 "Plastin 3" P13797 X 115561174-115650861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 209.3;Alveolar cells type 1: 211.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "NK-cell: 3.7;plasmacytoid DC: 12.2" "Group enriched" "Detected in many" 6 "dendritic cells: 12.2;NK-cells: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020433, HPA076083" Approved Approved "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA020433: AB_2670440, HPA076083: AB_2686773" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "unprognostic (6.10e-2)" "unprognostic (4.37e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (6.07e-5)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (5.15e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.72e-4)" "prognostic unfavorable (7.04e-4)" 120.8 32.4 33.2 36.3 40.6 1.4 71.4 44.3 43.6 83.7 22.1 46.4 21.8 120.5 76.2 117.8 68.3 83.1 57.9 30.7 34.9 113.2 202.0 139.8 24.2 43.5 40.1 101.5 31.4 12.7 11.7 78.4 42.2 43.6 31.8 11.9 46.8 103.2 31.4 119.5 25.0 119.4 38.4 99.8 37.7 22.3 39.5 27.2 175.0 48.8 41.9 75.4 88.5 47.9 206.2 207.1 176.8 51.5 174.3 161.7 269.3 208.2 233.1 194.5 233.9 225.0 167.2 0.8 590.0 171.9 140.6 256.7 190.5 339.1 314.2 2.9 235.8 19.4 234.6 95.0 157.5 0.1 9.6 103.1 159.5 302.7 211.1 315.3 429.5 16.8 0.5 0.3 188.9 59.7 0.4 2.3 234.6 88.0 243.2 0.4 117.8 4.9 233.1 109.1 0.6 36.9 436.8 107.9 89.7 253.7 60.2 3.0 474.3 314.5 53.9 324.6 422.8 7.8 30.5 4.2 137.6 0.8 133.4 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.4 0.0 0.1 0.0 0.1 3.7 0.0 12.2 1.4 0.2 33.2 40.6 44.3 43.6 30.7 34.9 43.5 40.1 42.2 38.4 39.5 47.9 209.3 211.5 88.6 26.8 2.0 124.9 121.4 79.6 48.9 0.2 5.6 25.4 17.9 24.3 79.4 99.3 0.0 4.0 1.6 3.5 13.7 59.0 8.4 33.0 39.4 130.5 13.2 4.4 12.3 53.8 105.3 74.3 31.1 64.1 0.0 60.5 64.2 92.1 3.9 0.0 47.6 6.9 38.7 5.0 21.7 8.0 51.9 3.0 56.9 40.3 0.6 26.4 0.0 1.5 97.9 68.6 6.5 82.8 1.6 80.7 2.2 22.0 31.2 1.5 52.6 19.8 132.3 1.2 17.7 65.5 134.1 4.5 3.6 131.1 11.1 100.6 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PLSCR4 ENSG00000114698 "Phospholipid scramblase 4" Q9NRQ2 3 146192335-146251179 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 77.3;Astrocytes: 151.1;Endothelial cells: 63.4;Hepatic stellate cells: 110.3;Oligodendrocyte precursor cells: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.5;ASC TERT1: 48.2;hTERT-RPE1: 62.1;HUVEC TERT2: 50.8;TIME: 106.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002276 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA002276: AB_1855479" "unprognostic (3.73e-3)" "unprognostic (4.03e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.62e-1)" "unprognostic (6.77e-3)" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (7.33e-2)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-4)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" "unprognostic (8.13e-3)" "unprognostic (2.97e-3)" 60.2 43.8 30.2 9.4 28.2 2.3 41.9 30.9 32.5 28.9 11.6 27.4 6.8 30.1 15.7 23.2 41.2 45.6 28.0 28.7 38.5 25.3 69.0 37.4 10.5 39.3 44.0 36.4 20.5 4.3 11.2 56.4 32.6 13.8 25.2 13.7 23.6 25.8 7.4 16.1 13.6 33.7 36.9 30.1 14.4 21.6 41.8 6.6 31.2 18.8 6.7 19.8 25.5 32.2 0.0 9.9 1.7 0.0 60.5 48.2 0.3 11.5 15.7 5.0 10.9 1.0 12.6 0.0 12.3 21.0 5.0 1.4 2.4 1.1 2.8 0.1 0.1 5.0 7.9 1.3 28.1 0.1 1.3 29.6 1.6 10.4 3.0 62.1 50.8 0.0 0.2 0.9 7.4 0.3 0.0 0.1 2.1 5.1 3.4 0.0 0.8 0.0 0.1 0.0 0.6 0.0 20.1 0.1 3.9 2.5 0.7 0.6 106.4 10.4 2.6 23.6 2.1 0.3 0.0 0.0 2.6 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 28.2 30.9 32.5 28.7 38.5 39.3 44.0 32.6 36.9 41.8 32.2 77.3 3.2 10.3 151.1 1.0 10.8 5.6 0.8 12.0 0.6 10.2 8.6 4.1 25.8 6.0 3.7 0.0 0.7 0.3 27.4 0.0 8.2 1.1 3.6 11.6 63.4 10.3 15.6 1.7 11.6 0.5 57.1 2.0 1.5 1.3 7.0 110.3 44.1 0.8 0.0 0.6 11.7 0.0 7.1 11.8 3.8 42.9 1.1 3.6 40.3 0.1 51.4 0.0 61.3 0.6 4.7 13.3 32.4 2.8 2.6 6.4 28.3 6.4 1.5 0.0 18.9 23.6 1.2 0.9 4.8 8.7 0.8 1.8 20.0 8.1 2.7 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PLXNC1 "CD232, VESPR" ENSG00000136040 "Plexin C1" O60486 12 94148577-94307675 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 57.0;Macrophages: 62.5;Melanocytes: 96.0;monocytes: 53.8" "Cancer enhanced" "Detected in all" "melanoma: 24.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.4" "Group enriched" "Detected in all" 4 "granulocytes: 16.4;monocytes: 8.6" "Cell line enhanced" "Detected in many" "HAP1: 33.3;Karpas-707: 25.8;SK-MEL-30: 41.4;U-266/70: 64.3;U-266/84: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066899 Approved Mitochondria NA NA 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA066899: AB_2685743" "unprognostic (1.49e-1)" "unprognostic (4.01e-2)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" "unprognostic (3.24e-2)" "unprognostic (4.67e-3)" "unprognostic (2.80e-2)" "unprognostic (3.49e-1)" "unprognostic (4.64e-2)" "unprognostic (1.78e-2)" "unprognostic (2.38e-1)" "unprognostic (4.02e-2)" "unprognostic (5.33e-3)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (5.48e-2)" 6.1 8.8 6.4 20.5 7.1 17.4 4.7 8.9 7.5 8.5 1.9 5.7 4.1 7.0 2.7 3.8 4.8 10.2 1.9 7.1 15.9 4.0 2.5 11.4 16.2 5.3 12.7 14.8 2.4 0.9 4.1 9.4 4.7 2.3 6.5 2.2 2.3 4.5 4.0 8.3 5.5 6.9 4.2 19.8 4.5 15.2 18.6 5.7 3.4 4.1 13.0 9.5 3.8 8.7 1.1 0.4 2.7 0.5 1.5 1.2 0.4 1.3 1.8 1.7 5.1 9.1 0.1 21.8 0.1 2.0 1.6 0.1 33.3 1.4 1.2 15.3 0.7 1.2 0.6 6.1 17.7 4.5 7.2 17.7 0.0 1.9 0.8 2.3 0.0 2.0 0.6 25.8 0.5 0.3 1.0 2.4 5.5 0.2 1.2 3.6 1.0 12.1 0.1 1.7 2.2 1.6 0.3 0.2 41.4 6.3 0.1 3.7 0.7 0.6 2.3 0.2 0.8 64.3 73.3 1.4 0.4 11.7 1.4 0.0 3.6 15.1 1.6 6.1 1.7 2.6 1.7 1.9 2.9 1.7 1.6 1.6 16.4 1.1 8.6 1.1 1.3 2.0 6.4 7.1 8.9 7.5 7.1 15.9 5.3 12.7 4.7 4.2 18.6 8.7 4.9 3.2 2.4 9.8 17.9 6.1 0.3 0.3 1.2 3.6 3.2 2.5 8.1 1.5 0.2 0.0 0.0 0.2 5.6 1.2 1.9 0.2 9.4 3.2 14.9 4.3 19.8 26.1 36.1 0.5 0.2 16.0 1.1 1.6 16.5 29.8 6.1 1.6 18.8 0.0 57.0 1.8 0.0 39.4 13.8 6.2 1.5 62.5 96.0 40.3 53.8 0.3 3.1 34.2 12.6 0.3 1.8 3.4 24.4 0.2 0.1 3.4 2.3 0.5 6.6 2.8 2.5 3.0 1.1 0.7 1.6 0.1 9.4 4.8 1.9 0.3 PMS2 "H_DJ0042M02.9, HNPCC4, MLH4, PMSL2" ENSG00000122512 "PMS1 homolog 2, mismatch repair system component" P54278 7 5970925-6009106 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010235, HPA066490, HPA070310" Approved Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "CAB010235: AB_2167281, HPA066490: AB_2685677, HPA070310: AB_2686250" "unprognostic (5.13e-2)" "unprognostic (6.55e-3)" "unprognostic (1.54e-1)" "unprognostic (1.43e-3)" "unprognostic (5.14e-2)" "unprognostic (1.29e-1)" "unprognostic (7.36e-2)" "unprognostic (1.02e-1)" "unprognostic (7.43e-2)" "unprognostic (2.35e-1)" "unprognostic (1.86e-1)" "unprognostic (7.38e-2)" "prognostic favorable (1.23e-5)" "unprognostic (5.31e-2)" "unprognostic (2.01e-2)" "unprognostic (3.67e-2)" "unprognostic (2.81e-2)" 5.3 5.1 6.7 5.3 7.2 5.8 6.5 6.3 7.6 4.8 2.8 4.8 5.7 4.9 5.0 5.3 5.7 4.0 4.1 7.4 5.8 10.4 4.7 4.4 8.4 5.3 5.6 5.7 3.9 11.0 4.6 4.8 5.5 5.2 4.7 8.4 5.7 5.5 4.5 11.9 5.3 5.3 4.4 5.9 5.0 4.0 5.2 8.8 9.2 3.5 8.9 5.1 4.9 7.0 15.1 16.7 12.9 32.2 9.0 13.6 10.9 7.8 5.8 6.6 5.6 14.0 9.9 28.2 8.7 10.9 17.2 19.6 19.2 6.6 8.0 11.3 7.2 12.0 12.5 10.1 15.9 15.8 9.4 15.1 14.8 5.4 22.3 11.4 13.7 15.2 22.9 12.6 11.9 15.5 5.2 17.1 13.3 7.6 9.6 16.3 15.3 14.0 16.4 11.0 11.9 25.7 13.3 23.0 16.2 18.0 27.1 11.8 12.4 9.3 21.2 14.2 14.6 19.8 32.8 27.5 7.2 15.3 22.9 5.0 2.9 1.9 4.5 4.1 4.9 3.4 3.5 3.8 3.0 3.4 4.4 3.4 1.4 2.3 1.8 3.1 3.4 3.4 6.7 7.2 6.3 7.6 7.4 5.8 5.3 5.6 5.5 4.4 5.2 7.0 12.2 12.8 8.2 11.4 13.6 5.0 9.3 10.9 15.9 13.2 10.7 11.3 3.2 12.8 9.7 11.0 22.9 9.4 15.2 1.8 35.2 5.5 9.9 11.0 14.6 10.1 5.4 8.4 14.0 3.3 6.3 6.6 8.2 11.8 5.1 11.4 7.9 7.6 5.2 30.3 12.2 2.2 10.2 7.1 5.9 6.6 12.8 6.3 7.2 5.6 8.7 7.8 20.6 3.5 8.3 4.7 2.6 10.1 9.6 12.6 2.2 39.5 9.3 14.3 26.3 10.0 8.0 34.5 11.7 10.5 8.1 12.7 11.4 11.9 2.6 11.1 PNLIPRP3 ENSG00000203837 "Pancreatic lipase related protein 3" Q17RR3 10 116427847-116477957 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 9.0;skin 1: 14.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.1;Early spermatids: 1.5;Late spermatids: 1.9;Melanocytes: 1.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "hTCEpi: 320.3" "Not detected" "Not detected" "HPA046202, HPA052009" Uncertain "Secreted - unknown location" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA046202: AB_10959739, HPA052009: AB_2681692" "unprognostic (2.62e-4)" "unprognostic (1.60e-1)" "unprognostic (6.97e-2)" 2.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 320.3 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 PNPLA1 "dJ50J22.1, FLJ38755" ENSG00000180316 "Patatin like phospholipase domain containing 1" Q8N8W4 6 36243203-36313955 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 23.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;granulocytes: 4.5;Oligodendrocyte precursor cells: 1.5;Proximal enterocytes: 1.5;Proximal tubular cells: 3.8;Suprabasal keratinocytes: 3.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 69.8;eosinophil: 18.9" "Lineage enriched" "Detected in many" 17 "granulocytes: 69.8" "Cell line enriched" "Detected in some" 4 "U-937: 17.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.57e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-4)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (7.37e-2)" "unprognostic (2.49e-1)" "unprognostic (8.89e-2)" "unprognostic (1.13e-2)" "unprognostic (2.95e-1)" "unprognostic (2.76e-2)" "unprognostic (2.70e-2)" "unprognostic (9.85e-2)" "unprognostic (2.06e-1)" "unprognostic (2.04e-2)" "unprognostic (1.65e-2)" 0.1 0.2 0.1 0.6 0.2 4.3 0.6 0.3 0.4 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 4.7 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 23.9 0.9 0.2 0.1 0.7 1.7 1.0 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 17.6 0.0 69.8 4.0 18.9 0.0 2.2 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.2 6.2 0.1 1.1 0.0 0.0 1.1 0.1 0.2 0.3 0.4 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.3 0.0 0.0 0.0 1.0 0.0 0.9 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.2 4.5 0.7 0.0 0.0 0.2 0.0 1.2 0.4 0.0 0.0 0.3 1.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 1.5 0.7 0.1 0.0 0.0 0.0 0.1 1.5 3.8 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 3.7 0.1 0.0 0.4 0.2 0.2 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 31.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 35.9;Cone photoreceptor cells: 18.8;Hepatocytes: 42.3;Rod photoreceptor cells: 37.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 16.7;LHCN-M2: 19.3" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.6 0.2 0.6 0.5 0.8 0.1 1.6 0.1 1.2 0.6 5.9 0.1 0.8 0.3 0.1 0.2 0.9 0.4 0.2 1.2 0.7 4.5 31.0 0.8 0.3 1.7 1.8 0.3 0.0 0.2 0.0 0.3 2.0 0.0 0.1 6.4 0.7 0.0 1.7 5.8 0.5 0.0 0.2 0.4 0.2 0.4 1.3 0.1 0.1 0.1 0.2 0.0 0.3 0.6 5.1 1.6 16.7 6.8 4.6 5.2 0.5 3.1 1.8 4.1 8.8 5.0 9.0 0.0 2.5 5.2 2.4 4.3 10.6 5.0 3.4 0.0 0.9 0.3 4.5 9.4 7.5 0.0 0.3 6.0 3.8 13.2 0.6 7.0 0.5 0.2 0.0 0.0 19.3 0.7 0.3 0.0 11.5 0.6 0.0 0.1 8.9 0.2 1.7 0.2 1.5 0.1 3.4 1.4 4.8 2.9 5.3 5.8 0.6 1.6 4.9 0.1 0.1 0.1 0.0 0.0 14.3 0.1 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.8 0.1 1.2 1.2 0.7 1.7 1.8 2.0 0.2 1.3 0.6 0.4 0.0 0.0 4.2 0.2 0.4 0.5 2.4 0.0 35.9 0.5 0.1 1.3 10.0 1.4 0.0 18.8 0.0 0.2 0.2 0.0 0.4 0.0 1.5 0.5 0.4 1.8 0.0 1.9 0.0 0.1 0.5 0.0 3.6 0.0 1.9 0.7 42.3 0.7 0.0 1.2 0.8 0.0 2.8 0.3 0.3 0.3 0.9 1.8 0.0 0.0 1.1 0.0 0.0 0.8 2.6 0.0 0.7 0.0 0.7 0.4 5.0 0.1 37.3 0.0 1.0 0.8 0.6 0.6 0.0 0.1 0.0 0.2 1.6 0.4 0.4 POLA2 FLJ21662 ENSG00000014138 "DNA polymerase alpha 2, accessory subunit" Q14181 11 65261920-65305589 "Metabolic proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.2;Spermatocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA037570 Supported Supported Nucleoplasm,Cytosol NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA037570: AB_10672280" "unprognostic (2.28e-1)" "prognostic favorable (4.61e-4)" "unprognostic (1.67e-2)" "unprognostic (7.44e-2)" "unprognostic (5.20e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (1.14e-1)" "unprognostic (2.87e-2)" "unprognostic (1.15e-2)" "unprognostic (4.05e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (4.09e-8)" "unprognostic (1.60e-3)" "unprognostic (8.26e-2)" "unprognostic (8.16e-2)" "unprognostic (6.25e-3)" 3.3 2.6 1.9 5.3 2.9 6.9 3.5 4.8 3.3 4.5 1.7 5.3 3.6 5.0 3.3 4.5 3.8 1.8 2.9 1.9 1.5 3.5 3.7 3.5 10.0 4.5 2.8 5.1 3.3 3.2 1.9 2.1 3.7 3.0 4.9 3.6 4.2 3.1 3.1 5.1 4.2 4.1 3.1 5.7 3.8 5.2 2.6 15.9 3.3 3.4 13.2 3.2 3.2 7.0 32.6 21.9 47.3 20.4 3.7 3.6 19.5 25.6 15.9 64.4 43.3 6.9 24.0 48.1 20.4 11.0 35.5 18.9 38.8 25.1 61.1 21.3 14.7 32.4 39.4 10.4 0.9 33.5 25.6 3.7 2.9 47.4 8.5 10.3 14.6 20.2 30.2 25.3 44.4 34.9 62.6 13.2 38.6 16.1 16.2 33.4 29.9 40.7 14.1 21.8 32.5 18.1 14.9 15.9 7.9 29.7 28.6 14.1 3.9 25.4 18.7 19.8 16.0 12.0 14.7 45.0 14.9 18.8 33.7 10.0 5.2 2.3 3.8 3.2 4.5 3.9 4.2 4.2 7.4 3.9 3.5 3.1 1.4 3.8 1.7 5.9 4.6 5.3 1.9 2.9 4.8 3.3 1.9 1.5 4.5 2.8 3.7 3.1 2.6 7.0 2.6 0.0 3.4 1.0 5.1 1.7 4.2 5.7 2.2 2.2 3.0 2.3 2.9 7.2 3.7 5.5 2.1 15.6 4.3 3.0 3.9 5.3 2.7 1.8 2.9 3.7 3.0 23.2 4.3 3.4 19.0 7.7 5.6 2.5 0.0 11.0 5.3 2.1 9.7 3.3 3.6 3.5 2.0 2.8 3.7 4.0 7.5 5.3 0.0 12.2 8.0 2.2 5.2 1.5 8.7 4.9 2.2 7.5 10.4 3.4 1.7 2.0 3.2 5.4 6.6 19.6 5.0 23.7 17.7 4.3 1.4 7.3 5.5 4.0 6.3 3.7 POLR1D "AC19, MGC9850, RPA16, RPA9, RPAC2, RPO1-3" ENSG00000186184 "RNA polymerase I and III subunit D" "P0DPB5, P0DPB6" 13 27620742-27744237 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 819.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039337 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Golgi apparatus" "HPA039337: AB_10672961" "unprognostic (1.33e-3)" "unprognostic (5.96e-2)" "unprognostic (4.35e-2)" "unprognostic (8.50e-3)" "unprognostic (1.98e-2)" "unprognostic (3.71e-3)" "unprognostic (5.33e-3)" "unprognostic (2.04e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-2)" "unprognostic (2.80e-1)" "unprognostic (5.18e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (2.56e-2)" "unprognostic (8.28e-2)" "unprognostic (6.45e-2)" 72.1 124.8 56.0 57.4 58.5 150.8 90.6 77.5 75.5 102.5 67.2 98.7 86.2 67.5 78.1 142.3 75.7 55.8 90.7 58.4 57.3 84.4 81.2 76.5 90.8 53.4 54.7 118.7 267.3 54.2 69.3 62.3 54.9 88.6 87.4 58.5 112.5 65.7 119.9 143.4 86.6 66.4 52.7 75.6 132.9 76.0 55.3 117.5 62.2 85.0 87.3 91.7 111.7 56.3 103.2 94.8 106.8 110.5 121.6 213.4 143.4 99.2 171.2 129.2 127.7 155.0 203.9 331.3 73.2 113.9 215.7 155.4 200.4 319.8 152.3 102.5 119.0 236.0 97.4 262.9 181.4 215.7 178.0 195.5 330.2 106.0 194.6 143.9 180.9 187.9 132.3 56.6 126.8 106.7 213.2 257.7 259.1 320.2 100.4 144.0 182.6 151.1 204.7 157.2 182.2 142.3 67.3 132.0 381.4 133.9 81.3 198.6 124.9 56.5 90.1 97.9 110.3 92.2 113.1 188.4 49.5 152.3 112.9 80.0 115.9 56.3 71.0 124.4 94.5 83.9 114.9 91.8 130.9 83.8 121.8 98.4 42.0 88.8 113.5 95.9 179.0 83.8 56.0 58.5 77.5 75.5 58.4 57.3 53.4 54.7 54.9 52.7 55.3 56.3 122.5 89.8 108.8 13.7 147.4 336.6 303.0 247.7 385.3 56.6 171.4 241.4 73.5 118.7 123.8 29.5 16.7 155.0 133.9 104.5 74.3 137.2 464.1 100.9 98.4 111.8 124.4 182.4 30.0 309.2 273.2 100.5 126.4 106.3 95.7 125.8 112.5 81.2 165.7 45.4 22.2 203.5 65.1 205.2 148.2 819.5 116.5 142.5 80.0 19.7 260.9 56.5 151.4 13.6 22.3 232.1 124.6 79.0 105.9 256.2 210.1 152.1 58.5 44.0 78.9 105.2 164.4 268.0 81.9 307.8 317.0 145.8 148.5 179.8 197.2 345.7 POLR2F "HRBP14.4, RPB6" ENSG00000100142 "RNA polymerase II, I and III subunit F" P61218 22 37952607-38041915 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 4 "melanoma: 1.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000827, CAB009882" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "CAB009882: AB_2299942, HPA000827: AB_1079834" "unprognostic (8.27e-2)" "unprognostic (7.50e-2)" "unprognostic (1.51e-3)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (2.73e-3)" "unprognostic (2.85e-1)" "unprognostic (5.87e-2)" "unprognostic (4.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.11e-4)" "unprognostic (9.08e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-1)" "unprognostic (7.86e-2)" 52.5 61.1 73.4 34.6 92.3 38.9 50.8 77.5 90.2 59.5 56.9 64.9 37.7 53.2 24.8 58.7 50.2 19.5 91.8 74.2 91.2 58.2 118.6 41.6 31.0 87.9 83.9 60.9 47.5 76.5 62.7 30.2 82.6 47.7 28.7 16.8 56.1 39.6 111.0 45.8 42.3 28.8 75.3 36.4 57.6 48.8 86.8 36.7 54.7 68.4 26.3 53.1 52.7 123.7 150.7 176.2 120.6 128.7 141.1 81.7 109.4 138.0 81.0 141.4 130.5 210.0 51.8 117.4 99.1 120.3 138.3 106.4 166.9 135.7 67.1 143.0 303.7 107.3 181.3 289.1 125.9 213.6 67.0 112.4 99.8 186.3 72.1 71.2 118.7 130.4 208.9 93.7 101.9 220.2 168.4 258.2 174.3 175.4 134.7 162.3 110.4 134.5 77.4 94.8 180.6 67.2 129.5 88.9 215.3 69.6 62.9 144.3 110.5 119.8 173.9 150.4 158.1 106.0 178.0 247.9 122.4 107.9 138.4 118.9 92.9 140.8 83.8 90.4 78.5 95.8 71.9 81.8 86.3 71.3 63.1 63.7 122.8 113.7 78.5 123.3 103.4 85.3 73.4 92.3 77.5 90.2 74.2 91.2 87.9 83.9 82.6 75.3 86.8 123.7 82.6 38.5 85.9 9.4 73.2 204.3 113.9 205.4 63.7 26.7 133.8 168.7 0.3 101.5 122.5 121.4 25.0 243.5 70.5 148.7 193.7 160.0 117.0 96.0 117.2 94.8 117.2 109.6 9.9 159.5 303.4 97.4 58.1 82.4 90.0 90.0 98.6 304.4 178.5 28.6 10.7 143.1 116.0 94.2 102.9 42.0 159.7 65.9 225.9 2.8 102.3 99.4 111.2 9.5 99.0 182.4 152.9 151.2 65.7 137.3 196.6 306.5 114.3 33.3 157.8 90.1 197.1 237.0 241.0 106.0 224.3 211.9 82.4 82.7 145.7 121.2 POLR3B "C128, FLJ10388, RPC2" ENSG00000013503 "RNA polymerase III subunit B" Q9NW08 12 106357748-106510198 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 24.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036466 Supported Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA036466: AB_10671842" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (4.80e-2)" "unprognostic (1.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-1)" "unprognostic (4.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.33e-1)" "unprognostic (3.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.09e-2)" "prognostic favorable (1.21e-4)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" 4.5 8.7 3.1 4.8 4.4 5.2 5.0 4.3 4.6 4.7 3.7 5.3 4.2 4.6 5.2 8.6 5.1 3.6 5.8 3.4 2.9 6.8 9.0 4.7 4.1 2.2 2.3 7.5 4.9 11.1 2.4 6.7 2.3 5.6 5.7 6.2 4.7 4.0 6.5 11.0 3.4 5.4 2.7 3.3 5.4 6.1 3.2 4.7 6.0 8.3 5.6 4.9 4.3 3.6 16.2 7.6 16.4 7.8 13.9 13.1 22.9 21.9 13.0 15.2 11.6 14.0 4.4 20.6 7.7 14.2 5.6 14.8 19.5 19.2 18.5 16.6 13.1 15.7 10.1 12.0 9.2 26.1 17.0 11.7 13.4 15.1 17.3 10.3 11.5 9.8 24.5 6.5 11.2 12.0 19.1 8.7 17.8 11.9 28.5 11.6 9.8 13.5 8.6 21.8 17.3 9.6 13.6 18.2 13.4 10.8 17.0 7.9 11.0 8.3 10.0 13.6 13.1 8.1 22.4 30.3 3.8 15.9 9.2 5.6 2.0 1.5 2.0 2.2 2.7 2.1 2.2 2.2 2.6 1.3 3.0 1.9 1.3 2.1 2.2 0.9 2.7 1.7 3.1 4.4 4.3 4.6 3.4 2.9 2.2 2.3 2.3 2.7 3.2 3.6 2.4 0.0 9.2 14.4 4.7 1.8 1.7 4.5 4.6 6.0 3.4 3.7 10.3 2.8 7.0 5.5 6.2 11.0 3.8 3.8 1.9 5.1 7.1 3.9 7.0 3.3 4.2 3.8 22.3 4.6 9.3 4.4 9.2 3.9 5.1 4.8 3.6 11.0 3.1 3.3 24.1 5.6 2.0 1.6 0.3 5.2 3.7 2.4 3.6 9.4 1.0 2.4 2.1 17.1 22.4 3.8 1.1 4.9 4.9 1.5 1.7 3.4 7.2 7.2 6.6 6.9 4.1 16.5 10.9 8.9 3.0 7.4 4.1 7.2 5.1 1.2 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036725 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 251.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 229.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" NA NA 3700000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA039163: AB_2676374" "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 37.0 20.6 5.3 16.4 5.6 0.2 30.4 6.8 7.0 42.3 12.2 41.4 37.3 31.0 36.5 46.8 14.8 33.5 44.4 5.2 5.8 24.9 28.9 27.0 7.6 6.4 6.3 16.2 30.3 20.9 6.2 48.3 6.2 23.4 49.9 4.9 31.7 24.0 41.2 20.2 32.3 45.2 6.1 7.7 22.4 9.0 6.7 5.8 47.2 33.3 14.2 45.8 28.8 5.8 19.6 16.8 6.4 136.2 229.7 104.6 26.9 54.4 42.3 27.8 56.7 28.1 128.6 0.0 94.2 147.1 83.3 21.9 18.9 68.6 22.1 0.1 33.1 27.8 60.7 32.8 58.9 0.0 14.7 65.8 51.5 32.5 34.0 49.9 58.1 0.0 7.9 0.0 20.1 116.5 0.1 0.3 11.6 120.9 29.0 0.0 14.5 0.0 87.7 67.0 8.5 14.9 106.7 51.1 12.1 77.8 72.0 61.8 64.8 52.9 32.7 18.5 23.9 0.2 0.1 0.4 45.9 0.2 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.6 6.8 7.0 5.2 5.8 6.4 6.3 6.2 6.1 6.7 5.8 214.1 32.1 16.5 6.2 1.6 47.4 52.3 251.7 30.7 16.9 63.9 47.5 46.4 61.5 149.0 73.5 4.2 60.1 0.6 134.0 29.4 201.5 1.7 52.4 94.8 106.5 12.7 0.0 0.8 126.4 65.2 198.2 55.0 50.8 1.3 54.2 80.7 57.8 43.2 0.0 2.2 177.1 207.5 4.2 40.3 4.2 112.5 6.9 32.0 5.6 3.2 2.8 0.0 1.0 0.3 90.3 181.0 100.1 0.6 48.2 189.0 81.7 110.5 4.4 39.5 22.7 87.5 41.6 37.8 118.6 49.3 25.0 3.4 61.2 117.0 81.5 PPP1R11 "CFAP255, HCG-V, HCGV, TCTE5, Tctex5" ENSG00000204619 "Protein phosphatase 1 regulatory inhibitor subunit 11" O60927 6 30066709-30070333 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 696.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 8 "cerebral cortex: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 51.5;AN3-CA: 65.6;fHDF/TERT166: 48.6;GAMG: 47.4;HBEC3-KT: 53.6;JURKAT: 76.7;RPTEC TERT1: 47.4;U-266/84: 64.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043266, HPA060174" Approved Approved Vesicles NA NA 43000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA043266: AB_2678400, HPA060174: AB_2684216" "unprognostic (2.00e-2)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (4.24e-2)" "unprognostic (3.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (1.18e-1)" "unprognostic (2.81e-1)" "unprognostic (1.74e-3)" "unprognostic (3.33e-2)" "unprognostic (2.68e-1)" "unprognostic (8.36e-3)" "unprognostic (1.74e-1)" "unprognostic (3.31e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-3)" 44.5 41.1 0.7 0.0 0.7 1.9 41.4 0.6 8.8 44.4 0.6 55.5 11.6 49.6 33.1 52.1 37.3 11.8 51.0 0.7 0.7 62.3 47.5 43.7 5.4 0.9 0.7 41.8 45.1 2.2 29.2 5.8 0.8 46.3 0.7 7.9 42.8 0.0 50.4 42.9 50.7 0.0 0.6 39.8 59.5 41.5 0.7 9.7 42.3 0.0 11.8 51.6 42.7 1.1 51.5 0.0 0.0 65.6 29.4 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 48.6 47.4 0.0 0.0 53.6 0.0 1.0 34.5 42.6 0.0 0.0 0.0 3.0 3.9 0.0 0.0 0.0 0.7 0.0 0.0 76.7 0.5 2.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.4 47.4 29.0 0.0 0.0 0.7 35.5 4.8 26.8 0.0 0.0 0.0 0.0 0.3 4.1 1.5 30.7 64.9 26.7 0.7 0.0 0.0 11.5 4.1 12.4 4.7 9.3 4.5 6.8 5.3 6.5 2.2 7.2 4.9 7.0 2.8 3.9 7.9 3.2 8.4 6.8 0.7 0.7 0.6 8.8 0.7 0.7 0.9 0.7 0.8 0.6 0.7 1.1 38.2 19.2 20.2 2.6 57.8 52.8 80.0 77.2 29.0 29.3 47.7 32.8 18.8 52.9 49.7 40.5 6.2 56.0 39.2 111.5 95.9 142.2 242.1 19.8 24.2 44.3 53.7 32.4 10.1 136.3 119.9 27.0 53.5 31.8 78.6 21.4 45.7 28.0 65.7 13.5 9.0 83.8 77.3 49.7 53.8 696.0 32.3 43.5 62.2 3.7 75.4 58.4 92.7 6.0 7.6 136.5 114.1 40.3 42.2 66.6 139.6 93.3 38.7 33.1 39.5 27.2 89.4 61.9 23.2 39.0 66.5 75.2 52.4 16.5 51.8 94.9 PPP1R1A ENSG00000135447 "Protein phosphatase 1 regulatory inhibitor subunit 1A" Q13522 12 54575387-54588659 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 259.7;skeletal muscle: 831.6;tongue: 271.1" "Cell type enriched" "Detected in many" 4 "Distal tubular cells: 1348.0" "Cancer enhanced" "Detected in many" "liver cancer: 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 8.8;NTERA-2: 29.4;RPTEC TERT1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007811, HPA041542" Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "CAB007811: AB_598171, HPA041542: AB_2677542" "unprognostic (6.39e-3)" "unprognostic (2.61e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (2.36e-5)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.19e-3)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (7.04e-2)" "unprognostic (2.71e-3)" "unprognostic (1.76e-3)" "unprognostic (2.88e-3)" "unprognostic (7.68e-3)" "unprognostic (2.17e-1)" "unprognostic (8.49e-3)" "unprognostic (7.49e-2)" 241.3 2.6 37.1 1.1 73.6 0.3 169.8 26.1 45.7 1.6 20.4 29.6 3.0 2.2 0.7 10.3 3.8 1.5 110.9 38.9 36.9 259.7 138.1 1.0 0.5 29.0 32.0 7.7 14.2 20.8 1.8 0.0 26.0 7.9 1.8 14.6 9.7 3.2 831.6 7.6 13.2 3.3 25.5 0.5 27.8 2.2 31.6 0.2 2.6 271.1 0.5 5.4 1.5 34.1 0.0 0.0 3.9 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 5.4 0.0 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 0.0 0.2 32.6 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 73.6 26.1 45.7 38.9 36.9 29.0 32.0 26.0 25.5 31.6 34.1 7.9 0.0 0.0 3.3 3.4 0.1 0.0 0.0 0.0 2.2 23.7 40.6 300.7 5.7 0.0 18.4 0.0 0.0 0.5 0.0 1348.0 3.5 1.6 10.4 0.5 4.6 2.4 2.7 3.1 0.4 0.1 24.5 0.0 13.8 0.0 21.0 6.4 218.4 0.6 112.7 1.8 2.1 0.0 3.8 0.0 1.9 1.2 1.6 0.0 0.0 0.0 3.7 0.0 0.0 0.5 2.5 0.1 1.2 0.0 0.3 0.5 156.8 0.0 2.8 0.0 19.2 21.6 0.2 5.9 0.0 0.3 0.0 0.9 4.2 2.0 0.2 PPP1R7 sds22 ENSG00000115685 "Protein phosphatase 1 regulatory subunit 7" Q15435 2 241149576-241183652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 968.8;Late spermatids: 1709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA034500, HPA034501" Supported Approved Nucleoli NA NA 960000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" Nucleoli "HPA034500: AB_2674192, HPA034501: AB_10670965" "unprognostic (1.63e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.16e-2)" "unprognostic (3.62e-2)" "unprognostic (4.38e-1)" "unprognostic (8.07e-3)" "unprognostic (5.01e-2)" "unprognostic (2.49e-1)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (1.15e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-1)" "unprognostic (4.51e-3)" "unprognostic (1.23e-1)" 59.0 55.9 71.3 54.4 94.7 68.1 50.2 65.5 82.4 46.4 68.3 66.0 58.8 48.5 61.4 80.3 81.3 40.2 100.5 77.5 69.4 64.6 76.0 53.9 78.7 67.2 67.2 37.5 60.0 55.8 42.6 44.5 65.7 94.5 64.2 58.0 63.1 54.0 100.4 64.3 61.0 55.0 66.5 48.7 58.9 158.2 67.2 66.8 65.1 64.4 80.8 58.9 52.9 75.1 117.6 69.5 77.4 98.3 149.7 149.0 106.4 126.3 114.7 85.2 119.8 38.1 145.6 60.0 37.1 108.9 128.0 112.1 127.9 119.6 130.2 156.4 126.1 105.1 112.4 151.4 96.3 147.0 105.9 116.0 92.7 101.1 74.2 115.7 128.5 121.0 108.0 86.2 202.0 155.8 132.0 112.6 106.3 185.7 64.5 90.4 200.9 121.9 159.6 116.7 104.6 82.8 67.6 157.4 120.3 86.4 93.8 156.7 127.7 76.8 72.5 146.1 103.4 90.8 59.6 162.8 215.2 154.1 103.7 107.9 84.9 108.9 64.6 87.6 68.3 71.6 76.5 77.1 81.3 66.5 58.5 67.6 66.5 75.8 96.2 48.4 121.5 89.9 71.3 94.7 65.5 82.4 77.5 69.4 67.2 67.2 65.7 66.5 67.2 75.1 50.5 57.7 54.5 17.6 47.9 27.8 48.6 126.2 25.6 41.5 44.6 36.8 98.4 45.8 105.5 44.1 16.7 89.6 46.9 53.4 121.3 90.6 968.8 83.6 39.3 45.9 25.7 48.0 33.8 145.9 92.4 47.5 34.7 53.4 59.5 48.9 32.9 49.9 100.5 32.0 19.4 68.7 109.9 40.7 46.3 1709.4 51.0 49.4 87.2 13.1 63.7 78.6 80.3 18.1 21.9 94.5 71.3 67.4 54.5 52.1 81.7 120.8 112.2 58.9 72.3 35.1 65.6 315.5 122.5 45.9 38.1 71.6 57.9 117.2 55.3 56.0 PPP1R9A "FLJ20068, KIAA1222, Neurabin-I" ENSG00000158528 "Protein phosphatase 1 regulatory subunit 9A" Q9ULJ8 7 94907202-95296415 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell type enhanced" "Detected in many" "Astrocytes: 294.1;Excitatory neurons: 262.8;Inhibitory neurons: 201.5;Oligodendrocyte precursor cells: 593.1;Oligodendrocytes: 308.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 6.8;NK-cell: 10.3" "Group enriched" "Detected in many" 9 "granulocytes: 6.8;NK-cells: 10.3" "Cell line enhanced" "Detected in many" "HAP1: 12.2;RH-30: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027726, HPA075591" Approved Approved "Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA027726: AB_1855653, HPA075591: AB_2732296" "unprognostic (1.05e-1)" "unprognostic (6.59e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (8.62e-2)" "unprognostic (6.19e-2)" "unprognostic (1.45e-1)" "prognostic favorable (7.17e-4)" "unprognostic (2.26e-2)" "unprognostic (1.89e-1)" "prognostic favorable (8.63e-6)" "unprognostic (2.74e-1)" "unprognostic (4.85e-2)" "unprognostic (8.47e-2)" "unprognostic (8.79e-3)" 1.7 7.0 13.0 0.9 20.1 0.2 4.9 6.0 14.5 2.7 0.3 8.2 1.7 3.0 4.9 1.6 5.7 2.4 5.2 14.4 7.5 4.7 0.4 3.7 0.3 5.9 6.9 3.3 8.8 6.7 4.6 2.5 8.0 2.3 3.8 18.5 9.6 2.8 4.9 0.5 2.2 2.2 6.6 1.8 4.9 6.7 10.2 0.5 6.6 4.9 0.3 2.6 0.5 13.9 0.0 11.0 6.6 7.6 0.0 0.0 5.3 0.5 0.1 1.0 0.8 6.1 3.7 0.0 9.0 0.5 0.6 0.0 12.2 0.0 1.2 0.0 4.5 11.4 4.5 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.8 4.8 0.1 0.0 5.5 4.9 1.8 0.0 11.8 0.0 10.7 9.2 7.3 7.4 0.0 0.9 1.4 4.0 2.1 0.0 0.0 0.1 4.4 0.1 4.0 7.3 11.5 0.0 0.2 0.0 0.9 6.8 0.0 0.4 0.0 0.0 0.2 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 10.3 0.1 0.3 0.0 0.1 13.0 20.1 6.0 14.5 14.4 7.5 5.9 6.9 8.0 6.6 10.2 13.9 4.5 41.7 66.6 294.1 2.4 0.4 0.9 0.0 0.6 58.2 24.4 12.2 127.7 18.6 16.5 47.8 56.3 21.6 3.3 15.7 3.9 25.1 17.9 40.3 4.5 6.8 38.9 2.5 262.8 7.0 3.1 9.4 21.4 57.1 5.7 39.5 7.9 1.5 1.7 1.7 201.5 15.0 4.1 0.6 0.3 15.3 2.5 0.8 7.2 41.2 0.0 46.9 3.1 593.1 308.4 6.6 14.4 0.7 2.7 4.8 1.8 9.6 20.6 88.9 0.0 118.4 9.2 25.1 12.6 0.5 0.9 33.1 1.7 22.9 15.7 2.6 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190048-52229518 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.76e-4)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 98.5 300.7 305.0 60.5 311.1 58.1 98.7 292.0 394.2 126.9 261.4 115.7 91.5 126.8 101.0 164.4 126.8 63.2 322.8 342.6 299.4 156.9 106.0 87.5 72.7 308.9 301.1 163.7 100.7 129.9 123.9 69.1 312.8 123.3 82.2 89.8 99.8 92.2 239.7 119.3 98.5 96.0 280.1 87.6 106.0 67.2 331.7 76.9 107.9 170.7 90.0 123.5 121.9 299.2 153.6 248.4 210.9 182.0 166.9 173.4 105.3 130.3 173.2 174.1 151.1 129.3 122.1 132.5 91.0 213.9 95.7 108.8 228.0 197.9 100.6 101.3 562.8 99.6 126.9 148.2 152.6 105.6 93.1 234.3 163.8 163.5 149.2 162.9 167.9 92.1 114.3 96.8 196.3 178.6 159.6 215.4 204.6 162.2 218.4 148.6 118.3 152.5 285.0 251.7 153.3 161.3 149.0 160.1 100.3 136.3 141.9 197.3 153.1 133.2 120.5 65.7 154.2 96.9 151.5 160.0 143.1 109.7 170.5 172.6 172.0 169.4 143.9 212.2 131.0 143.1 126.3 134.3 192.8 157.1 101.6 119.6 103.7 228.6 199.0 119.7 177.5 255.6 305.0 311.1 292.0 394.2 342.6 299.4 308.9 301.1 312.8 280.1 331.7 299.2 55.3 44.8 35.4 21.5 76.0 70.4 99.0 178.0 56.9 114.0 64.5 71.1 100.2 74.4 99.5 119.5 25.0 203.7 47.3 157.0 117.4 213.5 4.4 77.5 79.7 72.4 107.0 39.7 27.4 155.7 259.9 85.7 77.5 100.7 68.5 96.7 65.0 52.8 146.2 144.7 39.5 128.8 144.5 68.1 39.3 10.4 72.4 58.0 53.4 17.8 103.7 118.0 62.8 25.6 29.9 168.2 189.0 85.4 60.3 88.3 147.5 135.3 80.6 61.5 78.9 49.2 90.3 16.5 68.8 74.4 63.2 182.0 64.2 99.7 185.2 104.2 PPP2R3C "C14orf10, FLJ20644, G4-1, G5PR" ENSG00000092020 "Protein phosphatase 2 regulatory subunit B''gamma" Q969Q6 14 35085467-35122517 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 489.7;Late spermatids: 233.5;Spermatocytes: 239.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040835, HPA058834" Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Cytosol" "HPA040835: AB_10794152, HPA058834: AB_2683831" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (7.32e-3)" "unprognostic (5.33e-2)" "unprognostic (9.73e-2)" "unprognostic (1.10e-3)" "unprognostic (3.05e-1)" "unprognostic (7.85e-2)" "unprognostic (9.48e-3)" "unprognostic (1.17e-2)" "unprognostic (1.91e-1)" "unprognostic (2.18e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-3)" "unprognostic (8.55e-2)" "unprognostic (8.29e-2)" 19.9 15.5 23.5 23.9 25.0 42.8 17.1 24.4 41.6 18.1 23.3 18.6 21.0 16.2 16.4 12.5 14.0 18.6 22.9 23.8 25.6 14.4 16.1 17.7 31.0 25.3 24.4 15.9 10.2 17.0 17.6 18.8 25.6 17.1 20.3 15.4 13.5 14.1 24.9 7.1 22.5 21.0 24.9 24.4 16.2 71.6 24.4 26.4 12.4 25.7 25.9 22.3 10.4 27.5 41.2 21.8 41.7 33.9 32.4 54.5 29.6 33.0 32.0 41.0 48.0 18.1 32.2 47.2 13.4 33.9 15.5 17.6 20.0 13.8 60.5 47.8 19.3 26.2 11.9 65.2 43.3 51.2 51.7 41.9 14.4 29.0 19.7 24.0 55.7 26.2 25.7 46.3 57.4 28.4 46.4 43.1 37.1 27.4 24.3 50.2 27.1 32.8 15.8 24.1 39.9 37.5 41.7 27.6 57.8 19.9 17.9 57.0 47.9 41.3 17.3 36.0 34.9 44.8 52.4 92.8 22.8 47.9 48.1 66.5 41.6 86.9 23.4 52.5 27.0 31.0 24.8 29.5 36.1 33.1 22.0 26.9 76.9 33.1 42.7 16.3 40.8 34.0 23.5 25.0 24.4 41.6 23.8 25.6 25.3 24.4 25.6 24.9 24.4 27.5 35.5 16.0 24.7 32.7 40.2 11.5 23.3 31.7 9.6 15.9 18.8 14.7 26.3 17.2 25.8 20.2 4.2 19.4 48.1 29.1 33.2 31.2 489.7 23.1 28.1 33.8 31.2 69.7 28.3 36.1 26.2 26.5 19.9 21.7 33.7 31.3 34.6 22.8 61.3 8.4 30.4 26.8 32.6 49.7 36.3 233.5 28.3 42.6 28.4 24.4 71.5 28.7 46.4 36.2 58.8 49.2 22.3 30.5 37.4 24.8 37.8 43.2 25.1 21.5 32.9 24.0 43.1 239.2 58.6 19.6 13.5 34.8 45.2 36.2 24.6 30.5 PPP3R1 "CALNB1, CNB, CNB1" ENSG00000221823 "Protein phosphatase 3 regulatory subunit B, alpha" P63098 2 68178857-68256237 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 189.9" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005610, HPA047157" Approved Supported "Plasma membrane,Cytosol" NA NA 42000 "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Cytosol "CAB005610: AB_325975, HPA047157: AB_2679960" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (9.08e-6)" "unprognostic (5.90e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.59e-1)" "unprognostic (3.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (5.24e-3)" "unprognostic (5.35e-1)" "unprognostic (8.70e-2)" "unprognostic (1.24e-1)" 53.7 37.7 56.1 32.4 92.9 73.6 27.1 38.0 127.3 27.3 0.0 27.6 25.7 31.0 26.1 30.0 23.3 28.0 20.6 99.0 24.2 21.4 58.2 27.7 40.2 23.5 18.4 24.9 20.7 17.0 18.3 36.6 24.9 26.3 27.8 189.9 24.9 30.1 88.8 33.6 23.9 35.3 14.4 34.2 24.8 20.6 30.0 42.6 23.8 31.0 40.5 32.9 28.6 64.5 61.5 51.7 69.7 48.4 47.4 54.3 70.5 86.3 75.9 98.8 86.8 75.9 55.4 85.7 28.7 61.4 69.5 41.8 74.4 64.8 120.0 59.4 52.9 284.0 38.3 71.1 93.1 111.9 92.2 55.1 57.6 76.9 78.0 55.9 67.2 72.2 67.8 96.8 73.2 53.8 96.1 99.4 81.9 52.0 44.4 69.1 90.6 139.9 61.7 66.1 91.4 64.2 50.4 72.3 65.9 45.0 33.9 51.8 69.5 84.6 76.5 64.2 75.1 53.8 62.6 124.7 61.3 115.2 54.0 1.5 0.5 1.3 0.2 0.3 0.5 0.2 0.3 0.1 0.5 0.3 0.3 0.5 2.7 0.3 0.6 0.7 0.3 0.4 56.1 92.9 38.0 127.3 99.0 24.2 23.5 18.4 24.9 14.4 30.0 64.5 37.0 9.6 12.7 81.6 40.4 74.8 11.6 7.0 72.8 22.2 21.0 13.1 17.9 10.0 7.7 16.5 52.1 11.7 34.0 20.5 11.7 7.1 20.0 19.9 23.0 34.0 15.1 52.8 151.2 8.7 17.2 24.2 18.8 29.1 19.7 11.2 15.4 19.2 24.7 11.8 93.1 15.6 4.1 40.0 105.1 7.7 9.9 54.7 35.6 105.9 21.2 27.8 18.6 72.9 77.5 12.9 10.6 8.6 39.2 17.3 12.6 20.1 5.8 92.7 13.1 14.4 29.8 2.9 6.1 64.0 70.5 12.0 39.9 14.2 13.2 21.3 PRCC RCCP1 ENSG00000143294 "Proline rich mitotic checkpoint control factor" Q92733 1 156750610-156800815 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017151, HPA019463, HPA019481" Supported Enhanced "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" "CAB017151: , HPA019463: AB_1855672, HPA019481: AB_1855673" "unprognostic (6.12e-2)" "unprognostic (2.68e-1)" "unprognostic (2.68e-3)" "prognostic unfavorable (5.55e-4)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (3.03e-1)" "unprognostic (9.16e-2)" "unprognostic (3.27e-3)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "prognostic unfavorable (8.99e-15)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.02e-2)" 31.9 31.8 43.4 29.7 45.2 41.9 31.4 44.5 50.4 32.4 42.3 36.6 27.0 34.5 23.1 39.7 29.7 23.0 37.6 45.7 42.0 36.7 34.2 29.6 36.3 43.3 42.8 30.9 29.0 34.7 28.1 29.0 43.7 33.5 22.5 26.6 30.4 24.1 63.4 43.2 30.9 27.3 41.3 37.4 31.8 27.0 43.3 37.5 31.0 34.4 30.7 32.6 32.2 46.9 79.1 67.3 51.6 59.5 42.5 33.8 89.8 53.8 52.8 59.3 50.8 106.2 65.0 80.6 90.4 43.1 34.1 80.3 74.7 57.0 45.3 101.6 97.4 59.1 47.4 68.4 52.5 81.9 66.6 48.1 64.7 51.5 46.6 45.7 55.2 52.5 99.7 72.1 41.8 140.2 94.1 94.6 124.9 108.9 82.0 81.6 45.7 108.7 62.5 74.0 91.6 163.4 57.0 140.6 92.4 84.4 102.7 129.8 51.1 59.3 61.9 66.0 89.6 184.6 298.5 124.1 58.7 52.2 56.1 46.9 28.6 57.4 27.5 29.9 26.5 24.0 24.7 30.0 32.5 27.6 24.0 25.2 27.7 30.2 37.1 38.9 27.1 26.0 43.4 45.2 44.5 50.4 45.7 42.0 43.3 42.8 43.7 41.3 43.3 46.9 22.2 9.6 16.4 12.7 32.0 52.4 38.2 52.1 46.1 19.8 31.1 24.4 13.0 18.6 29.4 20.2 22.9 63.1 36.0 27.2 21.5 39.4 13.5 21.4 21.9 30.2 34.3 16.6 15.9 32.2 63.4 28.7 24.5 23.2 17.1 28.9 25.4 16.0 44.0 28.6 14.4 26.9 40.7 22.6 27.4 10.4 30.4 28.4 21.4 9.4 44.9 16.9 30.9 18.1 25.4 35.5 34.2 28.6 48.8 43.8 29.8 29.9 21.5 19.8 32.9 32.2 29.2 43.3 46.2 39.6 51.3 101.1 30.3 32.4 29.4 39.2 PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089241-123194266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9;urinary bladder: 9.0" "Cell type enhanced" "Detected in some" "Astrocytes: 15.0;Endometrial stromal cells: 6.5;Excitatory neurons: 7.9;Fibroblasts: 10.7;Late spermatids: 7.1;Oligodendrocytes: 11.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;HEK 293: 5.2;HEL: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.3" HPA030324 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA030324: AB_10670032" "unprognostic (2.33e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-7)" "unprognostic (9.30e-4)" "unprognostic (1.10e-1)" "unprognostic (3.43e-4)" "unprognostic (1.27e-1)" 0.7 0.1 0.2 0.3 0.2 0.0 0.6 0.2 0.3 0.9 0.6 4.9 0.2 0.7 0.1 0.6 0.4 3.3 0.5 0.1 0.2 0.3 0.1 2.9 0.0 0.3 0.4 1.9 0.3 0.1 0.3 4.2 0.4 1.3 1.0 0.2 0.1 0.1 0.1 0.2 0.6 0.7 0.3 0.0 0.6 0.3 0.2 0.0 0.8 0.2 0.2 9.0 0.6 0.3 0.0 0.0 0.0 0.3 0.3 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.1 5.2 1.1 0.5 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.4 0.4 0.3 0.2 0.3 0.5 0.0 0.0 15.0 0.0 1.9 0.1 0.0 0.0 1.0 0.6 0.3 1.4 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.1 3.3 0.6 6.5 0.5 0.0 0.0 7.9 0.2 0.3 10.7 0.0 0.5 0.0 2.4 0.0 0.5 0.8 0.0 6.4 0.1 0.0 0.8 3.5 7.1 2.1 0.4 3.6 4.7 0.8 0.2 0.0 3.0 11.0 0.1 0.0 1.2 0.1 0.2 0.0 0.8 0.2 1.0 0.0 0.7 2.2 2.3 4.4 0.2 1.3 0.4 0.4 6.1 0.0 0.1 PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105273218-105454062 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.7;Syncytiotrophoblasts: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol NA NA 1700000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB025414: , HPA031388: AB_2673855, HPA031389: AB_2673856, HPA031390: AB_2673857" "unprognostic (3.05e-2)" "unprognostic (9.09e-3)" "unprognostic (2.85e-2)" "unprognostic (5.46e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.33e-4)" "unprognostic (2.63e-3)" "unprognostic (2.39e-1)" "unprognostic (6.78e-2)" "unprognostic (5.81e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-3)" "unprognostic (2.74e-2)" "unprognostic (8.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" 17.3 17.4 7.2 14.6 8.1 14.3 17.7 7.4 12.0 15.2 7.8 32.1 23.6 15.8 12.1 21.1 13.0 8.7 22.5 8.8 7.3 11.3 19.0 16.2 13.6 6.7 7.7 16.0 19.2 20.5 13.0 17.8 6.8 11.6 37.5 15.4 18.6 9.0 84.8 33.4 25.6 15.3 6.6 14.3 18.7 21.4 8.8 16.4 12.3 46.9 16.2 21.4 17.5 8.5 22.3 26.9 27.9 32.1 63.1 37.1 27.7 28.6 27.0 37.2 39.0 35.9 14.2 28.5 26.8 33.9 35.0 33.3 41.8 86.5 42.7 41.8 37.4 38.1 21.7 40.0 25.3 40.5 26.2 35.8 53.4 27.6 71.7 28.0 35.4 50.1 67.4 49.8 45.5 38.8 25.8 41.4 27.9 44.2 25.0 41.1 48.4 18.3 28.2 53.8 36.0 51.8 25.3 42.0 21.7 35.3 17.9 61.9 36.1 17.3 23.9 21.6 36.2 14.2 9.7 38.5 30.4 42.6 56.6 5.5 15.2 8.4 16.3 16.8 16.8 9.3 14.2 17.1 16.5 6.9 12.9 15.5 0.8 19.9 22.7 7.0 13.6 13.5 7.2 8.1 7.4 12.0 8.8 7.3 6.7 7.7 6.8 6.6 8.8 8.5 6.3 3.2 6.7 22.9 10.1 10.8 6.8 12.0 5.7 5.1 6.0 5.5 14.8 7.2 13.6 7.3 14.6 28.2 14.5 19.3 5.9 10.4 1.4 6.6 15.1 10.1 19.3 11.2 79.7 11.7 35.9 10.6 24.5 11.6 13.4 11.2 7.5 15.1 15.0 13.5 48.3 29.4 10.2 14.2 10.8 3.2 10.8 13.3 5.4 27.2 19.1 3.3 5.2 28.6 18.7 18.0 29.1 9.1 11.0 5.3 18.5 8.8 4.8 10.4 0.0 8.3 10.3 3.9 18.8 12.9 8.5 67.9 16.1 14.4 38.2 8.5 PREX1 "KIAA1415, P-REX1" ENSG00000124126 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1" Q8TCU6 20 48624252-48827999 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.5;brain: 78.1" "Cell type enhanced" "Detected in many" "Astrocytes: 87.1;dendritic cells: 84.0;Kupffer cells: 104.7;Macrophages: 76.5;Microglial cells: 95.5;NK-cells: 90.6;Oligodendrocytes: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 157.9;SK-BR-3: 162.2;T-47d: 145.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001927 Supported Supported Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "HPA001927: AB_1079674" "unprognostic (8.07e-2)" "unprognostic (3.16e-2)" "unprognostic (2.15e-2)" "unprognostic (2.55e-1)" "unprognostic (7.47e-2)" "prognostic favorable (8.56e-4)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" "unprognostic (5.21e-2)" "unprognostic (1.13e-2)" "unprognostic (2.70e-2)" "unprognostic (5.86e-3)" "unprognostic (6.84e-2)" "unprognostic (2.31e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-2)" 14.8 10.6 32.8 37.4 56.4 52.5 15.0 43.2 47.2 12.3 1.2 7.0 6.3 4.0 1.4 6.4 4.7 13.0 6.7 32.1 42.0 4.8 5.2 26.8 36.6 52.1 52.0 2.5 5.3 6.9 7.6 11.7 53.8 4.8 6.0 3.9 5.3 3.4 6.6 3.5 12.7 7.7 43.5 42.9 8.8 6.0 45.3 9.8 9.4 8.6 21.8 12.3 3.2 78.1 2.3 6.1 78.4 0.0 1.3 5.7 27.2 2.7 3.5 11.2 2.8 0.4 0.3 16.4 49.5 7.2 21.4 1.0 4.1 0.2 7.5 3.7 2.0 2.4 8.8 0.0 4.6 9.0 51.1 6.3 0.0 25.7 0.0 7.6 68.4 7.2 0.2 0.6 14.8 157.9 0.2 24.7 3.1 8.1 6.4 24.1 22.8 9.8 0.5 0.0 16.5 2.4 14.7 162.2 17.8 4.4 145.0 67.4 77.2 4.5 15.6 0.2 4.6 0.9 3.5 20.1 72.4 17.8 24.3 4.5 1.9 2.2 3.7 2.2 2.2 1.5 2.0 3.2 1.6 1.4 0.3 1.1 9.2 1.8 2.0 1.3 7.3 2.0 32.8 56.4 43.2 47.2 32.1 42.0 52.1 52.0 53.8 43.5 45.3 78.1 43.2 3.2 6.6 87.1 35.4 2.5 0.3 0.4 1.2 0.3 40.0 21.5 3.7 2.8 2.6 1.8 8.4 0.7 84.0 0.9 0.0 0.2 3.5 3.5 4.7 24.5 1.2 14.1 13.3 1.2 4.4 10.3 4.1 6.2 1.3 0.7 20.7 1.9 32.1 0.0 4.6 1.8 0.0 104.7 28.2 2.9 0.9 76.5 8.8 95.5 47.1 19.4 90.6 49.3 190.2 0.1 1.0 0.4 23.3 0.7 0.3 0.2 4.5 0.7 0.0 18.1 3.3 2.2 11.6 0.4 2.4 9.3 63.9 41.2 4.5 0.7 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRICKLE1 "EPM1B, FLJ31937, RILP" ENSG00000139174 "Prickle planar cell polarity protein 1" Q96MT3 12 42456757-42590355 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 72.8;Excitatory neurons: 307.7;Inhibitory neurons: 122.2;Microglial cells: 64.6;Oligodendrocyte precursor cells: 114.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.6;naive B-cell: 11.5" "Lineage enriched" "Detected in many" 4 "B-cells: 11.5" "Cell line enriched" "Detected in many" 18 "HBEC3-KT: 1015.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001379, HPA050037" Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA001379: AB_1855703, HPA050037: " "unprognostic (2.44e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.22e-1)" "unprognostic (2.34e-4)" "unprognostic (3.53e-1)" "unprognostic (1.69e-2)" "unprognostic (5.89e-2)" "unprognostic (5.29e-2)" "unprognostic (7.77e-2)" "unprognostic (1.21e-3)" "unprognostic (2.29e-4)" "unprognostic (1.12e-1)" "unprognostic (8.95e-3)" "unprognostic (5.33e-4)" 6.3 3.0 3.7 5.2 5.0 1.7 5.0 0.0 7.2 12.5 0.0 4.2 2.6 12.1 1.6 2.4 6.4 10.0 13.8 4.2 0.0 5.0 1.7 9.5 4.6 0.1 1.3 12.5 2.0 1.4 2.0 5.3 0.0 5.1 2.2 4.2 7.8 5.6 3.9 4.7 2.4 12.7 0.0 14.8 2.9 6.0 3.9 1.6 7.9 4.6 3.4 5.5 6.3 1.0 7.7 4.4 17.0 0.5 12.4 13.1 0.5 11.0 5.2 3.0 5.1 0.5 16.0 0.5 31.4 1.6 0.0 2.9 12.5 1015.4 3.5 0.6 6.4 17.5 0.9 0.4 1.7 0.3 0.2 19.3 7.5 12.7 1.7 1.8 39.7 0.3 1.8 3.1 2.9 0.3 0.1 0.5 56.1 0.1 18.0 0.2 0.7 0.1 21.1 0.7 4.4 3.0 0.3 0.7 0.7 13.7 0.3 35.1 2.9 0.9 13.4 14.0 14.2 0.9 0.6 6.1 0.2 10.7 0.6 2.6 1.8 0.4 0.2 1.0 0.7 7.6 0.2 0.2 1.0 11.5 0.4 0.2 2.4 0.5 0.6 1.6 0.2 0.9 3.7 5.0 0.0 7.2 4.2 0.0 0.1 1.3 0.0 0.0 3.9 1.0 6.9 16.0 8.2 8.8 13.2 2.7 5.3 7.3 4.0 13.5 4.0 2.2 5.7 14.3 2.6 1.8 2.1 0.6 0.2 0.0 0.0 3.8 72.8 5.2 43.0 8.1 0.0 0.4 307.7 2.6 0.2 19.2 3.6 8.6 1.3 59.1 14.6 0.1 0.6 8.4 122.2 0.0 2.0 0.9 2.3 25.4 9.9 1.2 7.2 64.6 1.1 2.7 0.0 114.6 5.3 3.9 0.1 24.8 3.1 1.0 0.0 3.3 0.3 4.5 0.0 3.8 7.9 5.1 4.8 1.9 1.4 0.7 1.1 18.6 0.0 0.8 PRIM1 ENSG00000198056 "DNA primase subunit 1" P49642 12 56731296-56752374 "Predicted intracellular proteins" "DNA replication, Transcription" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.4;Spermatocytes: 118.2;Spermatogonia: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040010 Uncertain NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA040010: AB_10805599" "unprognostic (3.04e-3)" "unprognostic (1.67e-2)" "unprognostic (2.12e-2)" "unprognostic (1.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (2.40e-8)" "unprognostic (4.68e-2)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (1.56e-1)" "unprognostic (1.82e-1)" "unprognostic (1.98e-3)" "unprognostic (3.94e-1)" "unprognostic (2.16e-1)" "unprognostic (5.35e-2)" "unprognostic (6.53e-2)" 3.7 3.2 2.0 7.0 2.8 28.2 9.9 5.5 2.8 3.7 1.2 7.9 4.5 5.0 4.2 4.4 5.3 2.9 2.3 1.9 2.0 3.0 7.5 4.9 12.3 2.5 2.2 8.9 6.1 6.1 2.1 4.8 2.6 3.6 11.2 8.3 3.9 3.9 4.6 7.8 7.7 5.8 2.0 6.9 5.4 14.4 2.3 18.8 5.0 5.6 14.4 3.8 3.1 4.3 43.0 37.9 52.1 29.2 5.1 9.1 57.8 34.7 28.7 62.1 59.8 42.0 54.4 83.0 27.4 15.8 26.0 40.4 60.3 39.9 68.8 40.7 40.4 106.2 22.6 36.8 1.2 129.3 43.2 4.2 7.2 55.8 22.1 8.8 22.6 92.1 105.5 123.8 35.4 33.6 76.8 54.4 53.5 32.0 47.1 85.0 81.4 70.9 15.0 35.4 51.0 46.0 41.4 20.6 19.9 36.2 67.2 52.8 10.9 32.2 70.7 33.1 46.4 45.1 94.5 45.3 19.4 55.4 40.9 2.5 1.9 4.4 9.1 4.0 9.5 11.3 11.2 8.5 3.9 12.2 14.0 10.7 1.0 6.8 7.1 7.5 10.0 5.3 2.0 2.8 5.5 2.8 1.9 2.0 2.5 2.2 2.6 2.0 2.3 4.3 6.9 6.4 6.8 4.6 10.4 3.8 10.7 10.0 4.6 5.1 7.0 7.2 3.2 2.8 6.1 7.3 6.2 14.9 8.7 2.5 0.0 5.8 6.2 4.1 3.9 6.4 1.2 56.4 5.7 7.2 27.0 5.4 5.6 3.3 3.8 10.0 5.7 4.7 11.8 20.2 10.6 4.6 2.0 8.1 3.1 4.3 7.2 6.5 3.6 2.8 7.9 5.7 8.2 8.0 7.8 2.7 2.2 4.9 9.7 2.2 2.0 2.5 6.0 12.7 13.1 8.2 8.8 118.2 107.2 5.1 4.0 4.5 12.8 3.0 9.4 5.0 PRKCB "PKCβ, PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835983-24220611 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.0;lymphoid tissue: 47.2" "Cell type enhanced" "Detected in many" "B-cells: 185.1;Bipolar cells: 208.6;Excitatory neurons: 877.7;Inhibitory neurons: 320.2;Kupffer cells: 221.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 95 "amygdala: 28.9;basal ganglia: 53.9;cerebral cortex: 84.0;hippocampal formation: 35.3;white matter: 36.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 161.8;HMC-1: 154.8;K-562: 234.9;THP-1: 72.7;U-937: 64.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol NA NA 380000 "Cluster 6: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: AB_2680357, HPA054203: AB_2682416" "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.4 1.6 28.9 30.8 53.9 32.1 1.5 0.5 84.0 4.2 0.0 9.7 5.9 3.8 0.6 3.5 3.8 4.4 1.1 35.3 0.0 2.8 4.2 7.8 47.1 0.0 0.0 0.6 1.0 0.2 1.4 2.7 0.0 7.3 5.1 18.2 1.5 10.2 0.8 5.5 19.4 7.2 0.0 46.2 5.7 8.4 0.0 47.2 4.5 1.0 40.0 8.7 1.7 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 1.0 0.0 0.3 0.5 0.5 0.0 0.0 0.0 3.2 161.8 7.5 0.0 0.0 23.6 154.8 0.0 0.7 0.0 0.0 0.0 0.0 27.3 234.9 0.6 0.0 0.0 52.1 51.4 1.5 0.0 0.0 49.0 0.4 9.5 0.5 14.1 27.2 0.0 0.2 0.2 2.4 0.8 0.0 72.7 1.1 0.0 0.3 0.1 0.0 4.1 0.0 1.4 0.2 64.4 0.3 39.3 13.3 27.8 24.8 20.0 11.5 44.2 15.9 29.9 11.3 40.0 13.0 32.0 39.1 39.9 28.6 33.8 12.7 15.5 28.9 53.9 0.5 84.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 36.6 1.1 3.2 4.9 21.5 185.1 6.0 4.1 0.1 0.6 208.6 0.9 0.8 2.0 2.8 1.8 1.8 2.1 0.2 166.3 1.4 0.0 0.0 26.5 0.1 0.1 4.1 0.0 26.3 877.7 0.2 0.3 1.7 1.5 0.1 71.5 1.9 11.4 3.1 50.5 79.1 320.2 1.5 0.0 221.9 20.5 11.7 0.0 100.9 3.6 110.5 154.4 10.8 120.5 102.1 132.5 0.0 9.6 0.4 61.8 1.0 6.7 0.8 1.6 9.9 0.0 4.4 1.6 3.4 3.6 0.5 14.3 0.8 68.1 0.2 3.8 4.5 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050411-2185395 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Group enriched" "Detected in many" 4 "Late spermatids: 708.3;Syncytiotrophoblasts: 1107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 16.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in many" "BEWO: 44.5;OE19: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favorable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.7 11.1 23.6 4.6 25.7 2.1 5.6 58.0 41.3 4.3 0.0 13.2 29.3 2.2 7.8 16.0 9.5 4.4 9.7 23.7 10.2 16.0 11.0 31.6 8.0 18.6 8.3 2.7 12.5 14.7 17.6 43.8 19.0 8.4 11.3 14.8 10.8 3.9 0.3 13.8 28.0 1.6 5.6 10.5 8.9 31.9 7.2 3.7 21.8 0.6 7.8 5.8 8.0 24.8 14.7 9.7 3.4 17.2 0.0 0.0 44.5 1.2 0.5 11.1 0.7 23.8 31.0 0.1 27.4 3.9 9.4 25.4 20.5 25.5 7.9 1.0 21.8 0.0 15.2 33.5 3.2 0.1 11.0 0.6 14.9 0.0 8.6 0.0 0.0 4.0 6.6 0.2 0.2 17.9 0.9 0.0 6.4 41.9 22.5 0.0 0.0 5.1 18.6 16.0 24.1 18.7 11.6 27.5 5.2 28.7 17.7 4.0 0.0 0.1 13.1 0.1 0.1 6.8 1.3 0.3 1.2 0.3 16.8 0.3 0.0 16.3 0.5 0.3 2.5 0.3 0.9 0.6 0.0 0.4 0.8 0.3 1.1 0.9 0.0 0.3 0.9 0.3 23.6 25.7 58.0 41.3 23.7 10.2 18.6 8.3 19.0 5.6 7.2 24.8 0.9 121.8 72.2 2.3 6.5 13.0 11.8 11.0 10.2 27.1 11.3 11.0 1.4 5.7 21.1 7.3 4.2 118.7 7.5 48.9 7.9 12.3 224.4 14.0 4.7 6.3 10.2 6.6 39.5 10.7 66.3 3.1 17.9 11.7 8.2 12.5 10.0 16.5 14.5 62.2 35.2 25.5 10.2 0.8 2.9 708.3 9.6 4.4 7.2 2.8 4.5 19.1 8.2 13.0 41.3 14.2 45.7 8.6 7.4 19.5 78.4 24.7 22.1 25.9 0.0 0.3 4.1 28.3 28.4 13.4 13.4 1107.9 9.8 2.6 31.3 14.3 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "liver: 598.5" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 432.9" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.7" "Cell line enriched" "Detected in some" 16 "Hep G2: 156.1" "Low region specificity" "Detected in all" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" NA NA 5200000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.2 0.0 0.6 0.1 1.1 1.1 0.1 0.6 1.0 0.4 0.0 1.0 0.8 0.1 0.1 0.1 0.2 0.6 0.1 0.6 1.0 14.8 598.5 0.2 0.6 1.6 0.8 0.2 0.3 0.0 0.3 0.1 1.5 0.2 0.6 0.2 0.2 0.1 0.2 0.6 0.8 0.0 0.4 0.4 2.6 0.1 0.8 0.6 0.2 0.0 0.3 0.4 0.2 1.1 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.1 0.0 0.9 0.1 0.4 9.5 0.0 0.3 0.0 0.0 0.2 0.1 7.8 156.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.6 0.4 2.3 0.7 0.0 0.1 0.0 0.0 0.9 0.4 0.0 1.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 59.7 0.0 0.3 0.6 1.1 0.6 1.0 0.6 1.0 1.6 0.8 1.5 0.4 0.8 1.1 0.0 0.0 0.0 0.3 4.1 0.8 0.4 11.2 0.0 0.0 0.1 0.0 0.4 47.1 1.2 0.0 0.0 0.0 24.0 3.9 5.9 0.5 0.1 3.4 0.1 0.6 10.3 18.7 0.1 0.2 0.0 0.7 2.0 0.2 0.0 0.0 12.1 432.9 3.7 0.0 0.5 9.3 0.0 9.3 4.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 8.1 0.0 0.0 0.0 3.8 84.8 3.4 0.0 0.0 0.2 0.3 0.1 0.2 0.0 0.1 0.1 1.1 0.0 1.8 0.3 PRPF19 "hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4" ENSG00000110107 "Pre-mRNA processing factor 19" Q9UMS4 11 60890547-60906585 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012448, HPA038051, HPA059070" Supported Enhanced "Nuclear speckles" NA NA 71000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB012448: AB_2170868, HPA038051: AB_2675807, HPA059070: AB_2683896" "unprognostic (5.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (4.11e-8)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (9.37e-3)" "unprognostic (9.53e-2)" "unprognostic (1.54e-1)" "unprognostic (6.70e-2)" "unprognostic (9.62e-2)" "unprognostic (7.12e-2)" "unprognostic (9.04e-2)" "unprognostic (3.41e-3)" 46.1 70.6 89.8 49.8 87.9 67.0 48.8 73.7 100.2 57.4 60.2 54.5 42.9 55.4 34.2 81.7 57.3 29.4 47.9 91.3 94.1 50.4 77.2 34.6 64.1 92.0 80.7 66.6 69.4 79.8 79.3 42.9 92.9 62.1 51.8 46.1 56.5 48.2 75.2 80.3 49.5 47.9 75.6 54.3 54.3 30.5 81.1 78.5 43.4 38.9 73.7 58.7 55.9 84.5 197.5 147.0 161.8 116.2 92.7 80.8 155.6 102.4 137.5 200.2 149.0 162.7 141.1 280.5 145.2 98.2 120.2 179.0 229.2 184.6 153.4 207.0 153.4 232.4 111.3 184.9 134.2 308.6 161.1 86.3 137.0 154.4 171.9 58.7 158.7 167.4 248.2 155.3 99.5 270.6 328.9 249.5 292.6 150.5 197.7 285.8 165.5 227.5 101.7 127.5 142.3 172.9 126.6 208.3 178.0 73.1 225.8 170.2 101.9 89.6 147.2 161.8 171.2 147.2 223.3 287.9 111.6 208.6 138.6 4.2 7.8 2.0 2.4 3.8 1.7 0.9 1.8 1.7 3.6 2.4 2.2 2.0 0.5 1.8 2.3 3.9 1.7 1.0 89.8 87.9 73.7 100.2 91.3 94.1 92.0 80.7 92.9 75.6 81.1 84.5 15.8 19.2 23.7 10.1 26.7 42.1 35.2 40.2 33.0 32.0 24.6 19.4 17.6 20.0 28.6 27.6 10.4 94.7 16.2 20.4 27.4 48.5 21.6 21.4 19.7 27.3 39.0 45.2 19.8 51.6 90.2 24.9 23.4 28.4 22.8 25.4 20.0 46.1 46.3 62.2 22.2 40.0 32.6 23.0 21.6 3.6 37.0 19.3 26.6 11.2 41.2 25.4 21.6 10.1 11.8 33.4 27.7 38.7 31.9 40.4 27.8 27.9 17.8 25.3 46.0 22.4 22.6 25.2 38.0 37.4 41.6 40.6 24.8 24.8 55.1 26.3 PRSS16 TSSP ENSG00000112812 "Serine protease 16" Q9NQE7 6 27247701-27256624 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 58 "lymphoid tissue: 826.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 42.1;Extravillous trophoblasts: 25.4;Syncytiotrophoblasts: 31.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.1" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Cell line enhanced" "Detected in many" "hTCEpi: 20.4;RPMI-8226: 11.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.50e-1)" "unprognostic (6.95e-2)" "unprognostic (1.91e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.74e-2)" "unprognostic (9.21e-3)" "unprognostic (1.57e-1)" "unprognostic (7.89e-2)" "prognostic favorable (6.46e-5)" "unprognostic (1.57e-1)" "unprognostic (3.49e-2)" "unprognostic (5.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.62e-2)" 0.2 0.4 0.0 0.3 0.0 0.0 6.0 0.1 0.3 3.6 0.0 5.7 4.4 0.7 13.5 2.9 5.6 4.0 0.0 0.1 0.0 1.8 0.0 3.8 0.1 0.0 0.0 2.5 14.1 7.8 1.4 4.1 0.1 3.2 6.7 0.1 7.5 4.2 0.0 5.1 3.3 0.2 0.0 0.3 4.8 1.0 0.0 826.7 13.1 0.0 1.4 2.5 1.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.1 3.8 4.7 0.0 0.7 0.0 0.0 1.5 2.7 3.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 2.1 0.5 0.0 20.4 0.0 4.1 0.5 0.0 1.7 2.5 1.9 0.0 1.2 0.5 0.0 0.7 2.1 0.5 0.0 0.0 11.5 2.4 3.6 0.0 0.0 1.4 3.2 0.0 4.5 2.0 0.9 0.0 0.0 0.7 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.7 2.1 0.9 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 9.6 7.7 0.0 2.6 6.4 10.8 4.6 8.6 0.0 16.6 9.5 0.4 15.7 4.6 14.7 0.0 42.1 0.2 22.9 1.9 10.0 0.6 2.5 0.8 0.4 4.2 0.0 0.7 17.6 25.4 0.7 12.8 8.0 5.7 0.1 0.0 0.0 4.0 0.0 0.2 20.0 14.2 0.3 0.4 0.5 0.6 0.3 5.4 0.0 0.2 1.2 0.0 0.0 0.1 9.4 18.7 0.0 13.7 6.9 16.5 0.7 3.4 0.0 0.0 0.0 1.2 2.0 6.1 8.6 6.5 31.7 1.1 0.0 14.9 8.5 PRSS8 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 245.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 403.5;Extravillous trophoblasts: 648.4;Paneth cells: 262.6;Proximal enterocytes: 358.0;Syncytiotrophoblasts: 450.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 243.7;CACO-2: 165.9;CAPAN-2: 111.9;hTCEpi: 157.8;OE19: 79.6;SK-BR-3: 186.3" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in single" HPA030436 Uncertain "Secreted - unknown location" NA NA 4400000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" 0.8 0.4 0.3 15.0 0.4 0.2 25.5 2.1 0.6 31.1 6.7 129.4 155.7 9.9 113.0 136.2 15.4 47.7 0.4 0.6 0.2 90.6 28.0 54.1 0.3 0.3 0.2 0.6 139.4 56.0 8.4 51.0 0.4 49.0 72.6 0.0 245.4 8.5 0.3 115.3 151.8 3.5 0.1 0.2 156.2 0.5 0.2 15.4 50.8 0.0 11.8 4.9 56.0 0.2 63.4 0.2 0.1 0.2 0.0 0.0 243.7 0.0 0.0 0.0 0.0 165.9 111.9 0.0 1.3 0.0 0.0 73.5 0.1 69.7 0.0 0.3 0.4 0.1 0.3 6.5 0.0 0.0 0.3 0.0 157.8 0.0 2.4 0.0 0.0 0.1 1.9 0.1 0.0 68.1 0.6 1.4 20.5 79.6 0.1 0.5 0.0 1.2 7.5 13.1 0.9 0.7 0.0 186.3 0.1 18.8 42.8 0.8 0.0 0.1 1.9 0.6 0.4 0.3 0.5 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.1 0.6 0.6 0.2 0.3 0.2 0.4 0.1 0.2 0.2 0.4 99.3 60.1 0.0 1.0 37.9 82.7 108.9 76.2 0.5 74.4 39.2 0.3 62.9 107.4 42.3 0.0 168.8 0.8 403.5 29.4 192.4 0.0 35.2 11.4 2.6 9.6 2.7 0.1 224.4 648.4 3.5 82.6 109.5 7.0 0.0 0.0 18.2 22.8 0.0 0.2 132.1 87.5 0.3 2.7 0.0 0.6 1.9 3.6 0.0 4.2 0.3 0.0 0.0 0.0 240.7 262.6 0.0 0.1 66.0 358.0 28.6 21.2 0.1 0.0 0.1 4.7 0.0 0.2 81.9 54.0 450.7 2.2 0.0 150.8 91.0 PRXL2A "Adrx, C10orf58, FAM213A, MGC4248, PAMM" ENSG00000122378 "Peroxiredoxin like 2A" Q9BRX8 10 80407829-80437115 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Antioxidant "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 405.6" "Group enriched" "Detected in some" 7 "Adipocytes: 161.4;Cardiomyocytes: 161.5;Hofbauer cells: 75.1;Smooth muscle cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 166.0" "Lineage enriched" "Detected in all" 11 "dendritic cells: 166.0" "Cell line enhanced" "Detected in many" "ASC diff: 947.9;HaCaT: 276.4;HUVEC TERT2: 436.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009025, HPA024565" Enhanced "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA009025: AB_1078312, HPA024565: AB_1845519" "unprognostic (1.73e-2)" "unprognostic (2.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-2)" "unprognostic (3.14e-1)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (7.01e-2)" "unprognostic (3.54e-2)" "unprognostic (2.83e-3)" "unprognostic (3.32e-3)" "unprognostic (3.55e-1)" "unprognostic (6.78e-2)" "unprognostic (1.80e-1)" "prognostic favorable (6.11e-4)" 405.6 25.1 112.4 15.9 110.4 3.6 210.2 97.4 119.8 92.0 122.6 51.8 84.0 52.5 212.8 83.9 30.9 30.8 76.3 121.8 104.3 110.9 197.3 20.9 18.0 108.2 111.3 30.7 66.0 69.0 59.1 45.2 108.5 70.4 43.2 42.9 50.6 44.3 49.7 81.1 59.8 19.9 103.1 12.3 24.8 51.5 131.1 34.7 55.1 75.8 26.9 71.4 51.9 101.5 26.0 62.9 105.3 0.4 947.9 0.1 7.2 4.0 22.0 2.0 0.5 60.1 76.3 16.6 82.1 0.3 47.1 276.4 9.5 10.9 0.5 1.1 17.6 32.5 23.8 89.0 91.9 0.3 9.0 71.1 20.2 6.7 0.3 250.1 436.7 95.1 26.9 0.6 0.0 89.6 41.9 4.7 51.2 39.1 0.3 117.5 48.5 0.8 223.1 106.2 107.6 76.6 11.0 147.7 168.4 78.9 66.2 46.2 119.1 0.6 1.0 0.5 0.6 9.3 22.0 0.4 66.0 0.6 7.6 1.3 3.5 11.6 6.6 0.8 5.1 15.8 3.7 5.5 3.3 11.1 13.4 13.9 2.2 6.2 0.2 166.0 0.2 4.8 112.4 110.4 97.4 119.8 121.8 104.3 108.2 111.3 108.5 103.1 131.1 101.5 161.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.5 0.0 0.0 0.0 0.0 13.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 7.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.0 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PTGER3 "EP3, lnc003875" ENSG00000050628 "Prostaglandin E receptor 3" P43115 1 70852353-71047808 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 95.2;kidney: 81.2;smooth muscle: 68.0" "Group enriched" "Detected in many" 7 "Distal tubular cells: 225.0;Langerhans cells: 79.8" "Group enriched" "Detected in some" 7 "breast cancer: 4.1;renal cancer: 9.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 59 "basophil: 43.3" "Lineage enriched" "Detected in single" 59 "granulocytes: 43.3" "Cell line enhanced" "Detected in some" "ASC diff: 28.6;HAP1: 20.9;HDLM-2: 32.8;HEL: 15.6;T-47d: 72.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010689 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "HPA010689: AB_1855883" "unprognostic (1.53e-3)" "unprognostic (3.48e-1)" "unprognostic (1.11e-1)" "unprognostic (3.86e-3)" "unprognostic (1.47e-1)" "unprognostic (3.37e-2)" "unprognostic (4.80e-2)" "unprognostic (2.01e-2)" "unprognostic (1.24e-1)" "unprognostic (4.64e-3)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (8.83e-3)" "unprognostic (1.86e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-4)" 54.5 6.7 7.1 5.0 4.3 0.2 28.6 0.0 8.5 4.7 10.4 13.9 1.2 95.2 3.7 3.9 10.1 8.9 1.6 4.7 10.9 81.2 0.3 1.0 1.3 5.6 0.6 1.7 6.6 0.9 0.6 0.6 3.2 3.0 2.3 0.7 11.9 7.9 0.4 13.8 3.7 68.0 2.4 0.3 22.4 1.0 4.7 0.9 1.0 1.4 1.4 6.6 6.1 1.1 0.0 0.0 0.0 0.0 28.6 0.7 0.1 0.7 0.0 0.1 0.7 0.0 0.0 0.0 0.0 3.5 0.0 0.0 20.9 0.0 0.1 32.8 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.1 0.0 0.3 0.0 0.2 72.5 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.1 7.2 0.0 43.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 7.1 4.3 0.0 8.5 4.7 10.9 5.6 0.6 3.2 2.4 4.7 1.1 6.9 0.0 0.5 0.0 0.0 5.0 0.2 0.0 0.0 1.6 13.7 6.1 1.8 1.5 0.0 20.2 0.0 0.0 0.2 0.4 225.0 3.0 1.6 0.6 4.6 1.7 2.4 0.0 2.2 0.0 2.4 12.2 1.5 1.2 9.5 0.0 0.7 0.0 0.1 3.3 3.4 1.0 12.2 0.0 79.8 1.0 1.2 3.2 8.8 0.0 0.6 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.1 1.3 0.1 7.2 0.0 0.2 6.6 0.5 11.7 0.1 0.1 0.1 7.5 0.1 1.2 6.2 0.0 0.2 PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 254.0;Basal squamous epithelial cells: 93.9;Breast glandular cells: 105.4;Breast myoepithelial cells: 56.3;Club cells: 77.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HaCaT: 291.3;HBEC3-KT: 359.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" 3.1 0.8 1.8 1.2 2.3 0.0 20.1 0.6 3.2 13.6 10.2 3.3 2.3 10.7 1.1 16.2 1.5 7.5 4.2 4.1 3.2 0.4 0.2 1.2 1.1 4.0 8.1 1.8 1.7 22.8 2.9 3.0 0.4 5.2 1.6 0.2 8.5 2.4 0.7 2.0 1.6 3.0 0.2 3.6 1.8 1.3 8.6 0.4 1.8 1.7 1.0 9.2 15.2 0.8 1.7 9.9 0.0 0.0 2.9 2.8 0.1 0.3 1.0 0.5 1.3 0.3 7.9 0.0 0.5 2.6 9.1 291.3 1.3 359.8 0.1 7.4 1.7 0.5 1.8 0.1 0.8 0.1 0.4 0.2 19.7 9.1 34.4 0.9 11.2 0.1 0.0 0.4 0.2 0.1 0.1 0.0 1.4 0.4 16.7 0.1 1.5 0.6 34.3 0.3 0.2 0.1 16.4 0.1 2.1 11.5 0.5 0.1 5.6 1.6 8.9 5.1 77.8 4.7 0.1 12.1 7.5 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.8 2.3 0.6 3.2 4.1 3.2 4.0 8.1 0.4 0.2 8.6 0.8 1.4 0.0 0.0 0.7 0.4 4.6 1.9 254.0 93.9 0.3 105.4 56.3 0.4 0.0 77.5 0.0 0.0 0.0 0.5 0.0 0.0 3.5 5.9 0.9 4.7 4.5 0.0 0.0 0.6 8.9 0.0 13.6 0.0 0.8 0.0 2.6 0.4 0.2 0.0 0.0 11.2 0.0 4.1 0.3 1.3 2.7 0.9 0.6 23.2 1.0 0.6 1.8 0.0 0.0 0.2 8.6 0.0 0.0 6.2 0.5 0.0 0.3 14.8 0.5 6.6 8.0 6.7 3.6 0.2 7.9 1.4 0.0 0.5 0.2 0.0 0.2 PTPN6 "HCP, HCPH, PTP-1C, SHP-1, SHP1" ENSG00000111679 "Protein tyrosine phosphatase non-receptor type 6" P29350 12 6946468-6961316 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 131.8;lymphoid tissue: 153.5" "Cell type enhanced" "Detected in many" "B-cells: 214.6;granulocytes: 137.3;Hofbauer cells: 191.6;Kupffer cells: 146.5;Langerhans cells: 118.2;Macrophages: 152.1;NK-cells: 154.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 170.9;HL-60: 154.3;HMC-1: 648.7;THP-1: 259.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001466, CAB004572, CAB072845" Enhanced Supported Nucleoplasm,Nucleoli NA NA 6000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Nucleoli "CAB004572: AB_628251, CAB072845: , HPA001466: AB_1855930" "unprognostic (4.28e-3)" "prognostic favorable (1.87e-4)" "prognostic unfavorable (5.42e-4)" "prognostic favorable (6.65e-4)" "unprognostic (6.54e-2)" "unprognostic (7.92e-2)" "unprognostic (2.36e-1)" "unprognostic (1.44e-2)" "unprognostic (6.93e-3)" "unprognostic (3.57e-1)" "unprognostic (1.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.60e-3)" "unprognostic (1.98e-3)" "unprognostic (2.60e-2)" "unprognostic (5.91e-2)" "prognostic favorable (2.64e-8)" 14.4 15.6 3.7 102.5 3.9 131.8 11.0 4.3 4.2 11.1 6.0 21.9 30.4 6.2 10.2 12.8 13.9 20.3 4.9 3.6 5.2 12.2 19.3 49.7 153.5 7.0 4.6 2.9 11.9 13.7 10.0 19.8 6.3 11.7 21.3 0.7 17.0 9.0 2.0 18.8 42.0 12.3 5.9 128.0 28.0 3.1 6.3 71.3 12.6 4.5 127.3 27.0 7.5 10.6 16.4 30.8 0.2 0.1 0.1 0.0 28.5 0.0 0.0 0.0 0.0 16.5 36.0 11.9 8.4 0.0 0.0 18.3 0.3 21.6 0.0 7.3 6.5 170.9 3.4 13.9 0.0 154.3 648.7 0.1 15.4 0.0 6.5 0.0 0.0 60.0 0.3 1.3 0.0 34.5 55.4 92.2 8.3 38.0 5.1 50.4 0.2 86.5 16.7 30.2 2.7 0.0 5.2 24.9 0.2 20.9 7.7 259.8 0.4 0.0 0.2 0.1 0.2 0.4 0.2 5.5 0.4 66.3 0.5 676.7 368.3 1112.5 263.4 728.6 169.3 595.0 125.3 195.9 377.0 650.0 142.7 182.6 674.8 238.6 1117.7 98.7 146.8 789.3 3.7 3.9 4.3 4.2 3.6 5.2 7.0 4.6 6.3 5.9 6.3 10.6 10.5 6.4 13.8 0.7 214.6 9.1 8.2 18.8 29.6 0.0 8.6 10.0 2.1 11.5 15.3 5.5 0.0 25.6 77.7 16.0 15.6 15.8 50.4 12.1 1.5 7.5 24.7 22.9 0.9 15.4 18.3 3.0 25.0 11.8 137.3 10.9 8.9 11.6 191.6 0.0 0.9 13.2 18.3 146.5 118.2 10.5 0.9 152.1 14.2 3.7 99.7 0.5 154.5 2.0 0.1 12.6 16.9 0.0 53.5 3.9 22.8 14.3 17.2 0.5 6.6 1.6 4.0 0.3 1.3 14.6 8.7 18.5 86.2 24.5 15.6 7.8 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 208.6;lymphoid tissue: 329.9" "Cell type enhanced" "Detected in many" "B-cells: 525.2;dendritic cells: 1026.4;Macrophages: 534.1;monocytes: 554.9;NK-cells: 769.3;Plasma cells: 474.2;T-cells: 1049.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 209.9;HEL: 118.0;HL-60: 108.1;JURKAT: 266.4;MOLT-4: 161.1;THP-1: 87.0;U-266/70: 93.7;U-266/84: 91.2;U-698: 123.4;U-937: 94.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 24000000 "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" 32.8 11.6 3.8 248.5 3.3 208.6 13.9 4.4 4.3 14.9 6.9 26.4 27.4 11.3 5.6 15.1 8.4 45.7 7.3 3.5 5.6 7.0 29.6 68.6 329.9 12.9 8.6 5.7 5.6 4.0 2.9 23.5 11.5 11.6 30.5 2.0 13.8 6.6 4.6 5.7 42.9 25.3 7.9 202.5 37.9 5.5 6.9 306.9 7.0 7.6 251.2 62.1 5.2 14.7 0.4 0.0 0.2 0.2 0.0 0.0 0.8 0.3 0.3 0.1 0.0 0.0 0.1 209.9 0.3 0.7 0.2 0.3 0.0 0.2 0.4 0.6 0.0 118.0 0.2 0.1 0.0 108.1 0.7 0.0 0.0 0.3 0.0 0.4 0.5 266.4 2.4 3.3 0.3 0.1 161.1 65.0 0.5 0.2 0.2 4.6 0.4 0.3 0.1 0.1 1.2 1.8 0.1 0.4 0.5 0.2 0.3 87.0 1.3 0.0 0.8 0.8 0.4 93.7 91.2 123.4 0.1 94.5 0.4 226.1 480.0 521.4 634.4 885.8 541.8 249.0 437.0 618.1 385.8 245.8 489.8 494.1 844.3 506.9 1015.8 57.4 508.6 1340.6 3.8 3.3 4.4 4.3 3.5 5.6 12.9 8.6 11.5 7.9 6.9 14.7 12.6 44.8 62.3 0.7 525.2 15.8 0.9 0.0 4.0 0.3 6.0 9.3 4.6 5.7 14.2 1.8 0.0 0.6 1026.4 1.0 0.0 0.7 2.4 2.3 2.3 15.1 1.2 58.8 0.7 0.0 0.9 17.2 46.9 2.7 246.5 0.1 14.6 6.9 96.0 0.0 1.7 0.4 0.0 334.9 214.5 3.5 1.2 534.1 21.4 201.4 554.9 0.1 769.3 2.5 0.7 0.1 0.8 0.0 474.2 1.1 0.1 2.5 11.7 0.2 6.6 7.4 6.7 0.3 0.6 1.8 15.2 0.8 1049.1 5.4 0.9 0.8 PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4;skin 1: 31.9" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 2714.3" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 425.5;NTERA-2: 126.3;WM-115: 193.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" NA NA 3400000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavorable (9.36e-4)" 1.6 1.6 66.0 1.2 64.2 0.0 4.0 57.2 88.4 1.8 21.5 4.4 0.6 0.1 0.8 7.9 0.3 0.7 1.3 64.0 64.1 0.1 0.1 1.2 0.0 60.9 62.9 0.7 2.7 0.0 2.3 0.2 62.4 1.0 1.1 19.0 3.4 0.7 0.1 31.9 1.0 1.3 63.7 1.0 13.8 0.3 58.6 0.2 0.1 0.3 2.6 0.9 2.3 72.4 0.1 0.0 425.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 27.7 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 126.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 5.4 15.2 0.1 0.0 0.0 0.1 0.0 0.0 0.7 10.9 5.6 0.0 0.6 0.0 193.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 66.0 64.2 57.2 88.4 64.0 64.1 60.9 62.9 62.4 63.7 58.6 72.4 0.1 0.0 1.5 625.2 0.2 25.2 8.6 82.2 44.9 18.3 5.6 12.2 1.3 0.0 39.7 0.0 4.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.0 37.7 0.7 0.1 1.3 9.2 0.0 0.0 10.1 0.0 0.0 0.1 65.6 72.0 0.0 0.0 0.0 1.6 0.7 0.3 0.1 19.6 22.5 0.0 90.4 0.0 2714.3 3.6 0.9 0.3 0.0 1.2 1.8 0.0 0.1 16.9 6.6 0.0 1.2 1.7 0.1 1.6 14.8 21.5 0.3 0.2 0.5 0.0 7.8 PTX3 "TNFAIP5, TSG-14" ENSG00000163661 "Pentraxin 3" P26022 3 157436850-157443633 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 231.5;urinary bladder: 191.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 16.2;Fibroblasts: 44.7;Glandular and luminal cells: 24.0;Langerhans cells: 23.6;Macrophages: 27.0;Melanocytes: 14.2" "Cancer enhanced" "Detected in many" "glioma: 22.5" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.9;thalamus: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1219.3;ASC TERT1: 1751.7;BJ hTERT+: 1201.8;HHSteC: 2261.1;HSkMC: 2364.2;hTEC/SVTERT24-B: 1276.5;TIME: 1761.1;U-2197: 1605.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069320 Approved Approved "Plasma membrane" "Secreted to blood" NA NA 1090000 970000 "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA069320: AB_2686118" "unprognostic (1.93e-2)" "unprognostic (4.96e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (8.35e-9)" "unprognostic (5.79e-3)" "prognostic unfavorable (6.36e-4)" "unprognostic (6.03e-3)" "prognostic unfavorable (8.75e-6)" "unprognostic (2.45e-1)" "unprognostic (6.69e-2)" "unprognostic (7.60e-2)" "unprognostic (2.63e-1)" "unprognostic (2.76e-9)" "unprognostic (6.03e-3)" "unprognostic (5.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.92e-3)" 231.5 11.1 0.4 38.8 0.4 89.0 57.9 0.6 1.9 2.8 1.1 13.0 0.8 2.5 0.5 2.9 21.4 7.7 46.8 0.6 0.5 6.8 2.6 83.2 0.9 0.7 0.6 1.4 41.6 1.1 4.4 11.4 0.6 6.9 2.3 0.4 5.4 0.5 5.2 25.4 9.7 5.7 0.3 23.6 24.8 0.7 4.0 1.6 5.8 0.5 0.3 191.7 3.1 0.4 1.2 0.0 752.4 0.2 1219.3 1751.7 0.3 132.3 1201.8 56.2 60.9 0.7 7.9 0.2 460.6 157.4 87.6 0.0 0.3 1.1 110.5 0.8 0.3 2.0 0.1 0.0 2261.1 2.5 0.0 2364.2 0.8 1276.5 429.8 110.2 266.4 0.1 0.3 0.0 380.1 0.0 0.3 2.9 11.2 0.0 4.6 0.2 0.0 0.2 5.3 53.1 6.0 0.8 7.6 1.0 0.9 0.1 0.6 2.4 1761.1 252.2 12.2 1605.1 23.0 0.2 0.5 0.9 52.8 6.4 74.2 0.0 0.3 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 1.9 0.6 0.5 0.7 0.6 0.6 0.3 4.0 0.4 2.3 0.0 1.7 0.0 0.1 1.7 1.7 0.3 0.0 1.8 3.6 0.6 0.6 0.0 1.3 0.0 0.0 0.1 0.1 0.0 0.0 7.2 2.4 16.2 10.3 5.1 0.0 0.0 0.5 0.0 0.1 44.7 0.0 24.0 0.0 0.7 3.3 0.0 2.6 0.0 1.0 0.0 0.0 10.0 23.6 1.2 0.3 27.0 14.2 0.0 2.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.8 0.0 4.0 7.2 0.0 0.4 0.4 1.0 0.3 0.4 0.0 0.0 0.4 PUF60 "FIR, RoBPI, SIAHBP1" ENSG00000179950 "Poly(U) binding splicing factor 60" Q9UHX1 8 143816344-143829352 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 332.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045733, HPA052096, HPA059714" Enhanced Enhanced Nucleoplasm NA NA 70000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA045733: AB_10960503, HPA052096: AB_2681722, HPA059714: AB_2684110" "unprognostic (3.49e-2)" "unprognostic (8.78e-2)" "unprognostic (2.66e-1)" "unprognostic (4.05e-2)" "unprognostic (1.81e-2)" "unprognostic (3.47e-2)" "unprognostic (1.51e-2)" "unprognostic (4.34e-3)" "unprognostic (2.64e-2)" "unprognostic (1.07e-2)" "unprognostic (1.75e-1)" "unprognostic (5.45e-2)" "unprognostic (2.36e-2)" "unprognostic (2.64e-2)" "unprognostic (7.00e-2)" "unprognostic (2.28e-2)" "unprognostic (3.42e-2)" 71.6 73.5 7.9 11.0 7.6 39.6 75.5 8.1 22.9 71.4 5.3 84.8 22.3 84.9 5.9 84.9 76.3 7.3 88.5 7.8 15.4 82.8 124.3 64.0 17.7 12.2 11.6 57.2 62.9 11.7 71.0 19.2 14.1 67.2 5.8 1.3 63.3 17.8 125.5 108.7 69.5 10.5 7.3 72.3 73.2 70.8 14.5 15.9 59.8 9.0 9.7 74.5 68.6 12.4 95.7 211.5 36.7 31.3 16.6 15.6 62.7 74.4 27.4 70.3 75.1 95.4 103.9 89.4 71.2 58.9 52.8 83.0 86.5 91.4 3.6 91.4 147.7 110.2 117.0 106.3 60.4 38.5 70.0 45.4 61.8 89.8 26.9 21.1 69.0 92.1 88.7 37.4 20.5 332.5 156.1 26.4 77.8 63.3 191.6 84.2 42.9 91.8 19.5 91.8 71.5 80.3 101.6 40.4 77.7 9.1 116.7 21.4 79.0 72.9 176.2 85.7 98.6 66.7 103.9 109.7 70.7 73.3 71.9 90.8 112.6 99.8 129.0 133.7 139.3 116.8 103.1 128.6 127.1 135.9 98.6 113.1 58.8 132.6 137.6 76.8 139.0 193.9 7.9 7.6 8.1 22.9 7.8 15.4 12.2 11.6 14.1 7.3 14.5 12.4 70.2 38.5 46.4 21.5 64.7 107.7 102.1 197.4 65.4 62.8 51.3 67.9 63.7 51.5 103.0 29.5 29.2 146.6 56.4 98.0 92.0 110.7 20.5 65.6 55.3 67.3 66.9 65.0 8.2 89.8 134.3 68.4 74.9 60.3 55.8 75.0 41.7 76.8 101.1 43.7 8.3 75.9 118.0 44.0 62.3 47.8 64.0 52.3 90.7 6.5 105.2 182.6 81.4 9.5 23.7 98.2 91.4 59.0 52.7 83.0 91.9 118.1 85.4 64.8 65.7 57.1 122.9 104.2 128.5 63.1 107.1 173.3 74.2 99.3 97.7 81.2 PXMP2 "MPV17L3, PMP22" ENSG00000176894 "Peroxisomal membrane protein 2" Q9NR77 12 132687587-132704985 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 312.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.3;Hepatocytes: 577.4;Proximal enterocytes: 333.3;Proximal tubular cells: 303.7" "Cancer enhanced" "Detected in all" "liver cancer: 43.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 85: Liver - Metabolism" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.12e-2)" "unprognostic (7.96e-2)" "unprognostic (4.70e-3)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (7.39e-3)" "unprognostic (2.83e-1)" "unprognostic (2.44e-2)" "unprognostic (3.02e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.75e-4)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.71e-3)" "unprognostic (3.04e-1)" 24.8 14.7 23.7 7.5 24.3 23.4 18.7 24.5 29.8 14.3 37.7 49.5 52.1 14.9 22.3 16.2 18.7 15.4 62.9 28.5 24.1 58.2 312.0 12.9 11.5 24.1 24.2 23.0 42.5 14.5 9.3 8.1 22.9 19.8 39.2 7.5 18.6 9.7 42.3 16.8 55.1 9.5 23.0 13.1 98.2 9.1 24.9 25.9 14.7 30.5 10.7 15.9 12.8 23.5 60.5 24.8 36.6 34.1 21.5 16.6 21.4 21.0 19.4 44.7 39.6 30.3 22.4 37.2 24.9 30.0 15.7 42.0 49.1 26.6 24.3 21.3 77.8 33.2 43.9 33.8 41.7 24.8 14.4 21.7 21.8 18.6 14.7 31.2 12.1 56.2 58.2 28.4 23.8 54.2 78.9 39.2 35.7 70.0 33.9 80.1 39.2 30.6 32.9 25.2 69.0 22.5 45.6 23.6 29.6 28.1 63.2 56.0 14.3 21.9 51.1 19.1 35.6 25.7 26.7 60.6 24.6 34.9 17.7 0.0 1.2 2.9 2.3 0.6 2.1 2.5 1.8 2.4 2.1 2.7 1.8 1.5 0.7 1.5 0.6 6.3 3.1 1.2 23.7 24.3 24.5 29.8 28.5 24.1 24.1 24.2 22.9 23.0 24.9 23.5 10.9 3.2 7.2 8.1 8.2 8.4 20.0 10.6 15.4 6.1 50.3 51.1 35.8 138.7 6.0 25.8 4.2 60.1 7.3 187.3 166.3 16.5 18.7 11.8 16.9 14.1 18.7 55.9 5.9 10.3 36.6 17.0 65.7 17.4 4.5 32.4 46.8 577.4 34.9 0.0 7.1 85.1 2.0 19.2 9.4 38.8 31.1 8.1 12.4 5.6 2.7 45.5 13.4 4.5 1.0 10.2 143.4 35.0 20.9 28.1 333.3 303.7 2.1 7.3 19.7 7.5 14.8 44.9 30.2 31.2 10.7 28.5 8.1 12.4 158.6 23.2 PYGO2 ENSG00000163348 "Pygopus family PHD finger 2" Q9BRQ0 1 154957026-154963853 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023689, HPA074813" Supported Supported "Nucleoplasm,Plasma membrane" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane" "HPA023689: AB_1855974, HPA074813: " "unprognostic (1.49e-2)" "unprognostic (1.33e-1)" "unprognostic (6.96e-3)" "unprognostic (2.58e-2)" "unprognostic (5.85e-2)" "unprognostic (4.32e-3)" "prognostic unfavorable (3.88e-6)" "unprognostic (2.45e-1)" "unprognostic (2.07e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (3.74e-1)" "unprognostic (7.40e-3)" "unprognostic (1.63e-2)" "unprognostic (2.81e-2)" "unprognostic (2.17e-1)" "prognostic favorable (1.76e-4)" 14.6 30.6 30.0 16.7 30.3 6.5 15.3 29.3 29.8 21.4 21.1 23.5 19.0 19.1 23.5 24.2 20.3 12.7 15.5 29.9 34.0 24.7 20.1 15.7 26.5 30.5 30.8 27.2 18.1 27.5 32.4 16.3 29.1 23.5 15.3 12.7 23.2 23.3 18.9 22.4 24.4 15.7 29.8 28.2 21.6 16.1 35.3 22.5 26.2 15.9 27.8 21.2 20.0 32.3 28.1 19.4 40.4 36.0 39.8 19.5 37.0 17.1 23.0 26.5 22.7 26.1 34.2 34.9 26.4 19.9 28.7 37.2 35.6 23.7 17.4 34.7 25.1 27.9 32.7 23.6 18.5 25.8 23.9 16.2 33.8 23.9 20.0 30.0 16.5 52.5 37.1 57.6 25.2 42.8 36.0 30.0 43.3 55.7 34.2 40.2 25.7 55.6 27.1 26.1 48.4 71.8 27.0 48.5 34.9 39.1 59.7 45.9 14.1 23.5 35.1 25.6 25.1 56.8 54.3 37.1 19.6 32.4 31.8 2.3 3.9 10.9 8.0 6.5 10.0 6.9 10.3 10.7 4.1 7.5 11.0 8.7 3.8 6.3 8.4 3.9 5.8 6.2 30.0 30.3 29.3 29.8 29.9 34.0 30.5 30.8 29.1 29.8 35.3 32.3 7.0 9.6 4.9 5.5 12.6 5.5 3.8 5.8 7.4 11.8 14.3 10.0 5.3 5.7 7.4 12.9 2.1 15.5 14.1 10.3 19.6 6.2 3.4 5.7 7.5 6.8 5.4 12.4 6.3 5.9 12.6 5.8 9.7 7.4 0.0 9.3 7.1 9.4 6.5 21.9 4.3 10.6 6.1 6.6 3.5 2.2 9.0 5.6 5.4 6.5 6.4 10.6 8.2 5.5 4.7 9.7 9.1 9.1 11.5 4.9 12.0 9.8 4.0 6.0 6.6 5.4 6.9 5.9 12.2 9.8 5.3 11.6 11.7 9.3 8.4 3.7 PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: AB_2269494, HPA039717: AB_2676644, HPA046200: AB_10965556" "unprognostic (3.03e-2)" "unprognostic (1.00e-1)" "unprognostic (5.65e-2)" "unprognostic (8.82e-2)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.44e-2)" "unprognostic (3.94e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-2)" "unprognostic (1.59e-2)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" 24.5 30.8 19.8 24.0 20.2 22.5 27.9 21.5 24.8 26.1 22.9 31.1 31.6 22.1 41.5 72.3 22.7 19.8 21.8 19.5 20.7 26.3 43.0 20.8 35.4 20.5 20.6 17.1 28.0 26.3 22.3 22.8 20.5 31.2 30.0 17.4 34.0 15.9 29.8 41.9 29.5 19.8 20.1 31.1 24.1 25.9 20.1 33.2 27.0 29.0 42.1 24.8 31.4 20.2 50.3 39.1 56.1 31.4 33.4 43.2 92.6 36.1 43.1 33.3 28.0 57.7 57.9 62.9 53.6 35.1 15.4 38.6 43.6 77.1 26.7 48.6 32.7 51.0 35.1 71.8 40.7 59.7 44.7 39.2 48.8 37.7 56.0 42.2 35.9 27.3 44.5 67.4 39.7 75.3 38.6 105.7 98.3 56.7 20.2 34.3 22.3 72.5 69.5 69.8 37.7 43.4 46.2 61.1 33.1 51.8 74.5 124.0 28.2 20.0 28.3 31.5 26.6 35.5 58.2 97.2 34.2 40.9 31.9 17.5 79.8 75.8 58.5 92.2 72.3 98.1 105.4 82.2 120.2 88.2 68.7 69.5 19.1 53.1 66.5 65.6 186.0 87.2 19.8 20.2 21.5 24.8 19.5 20.7 20.5 20.6 20.5 20.1 20.1 20.2 16.2 19.2 17.3 0.0 28.6 0.0 29.4 0.0 21.1 12.7 41.7 38.4 0.0 25.8 14.2 23.9 8.4 84.3 21.1 29.8 78.2 40.6 15.2 21.1 17.0 16.3 7.3 32.2 0.0 50.6 76.3 17.6 22.4 21.1 18.9 14.5 22.9 44.3 55.2 6.7 0.0 32.1 0.0 47.7 0.0 11.7 23.3 42.8 0.0 0.0 110.4 55.7 48.4 0.0 0.0 54.1 33.7 23.7 21.9 34.7 66.8 61.3 16.8 13.6 13.1 18.0 15.7 23.8 25.6 63.1 0.0 62.0 29.6 16.5 29.3 34.3 PZP CPAMD6 ENSG00000126838 "PZP alpha-2-macroglobulin like" P20742 12 9148840-9208395 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 81.6" "Group enriched" "Detected in some" 4 "Early spermatids: 26.2;Hepatocytes: 26.4;Late spermatids: 11.0;Oligodendrocyte precursor cells: 8.5;Respiratory ciliated cells: 24.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.0;liver cancer: 0.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Group enriched" "Detected in some" 9 "HeLa: 5.7;SiHa: 2.5" "HPA041403, HPA041471" Supported "Secreted to blood" NA NA 15000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA041403: AB_10804003, HPA041471: AB_10795636" "unprognostic (8.48e-3)" "unprognostic (1.12e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-4)" "unprognostic (4.79e-1)" "unprognostic (3.50e-2)" "unprognostic (2.04e-4)" "unprognostic (4.57e-2)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (9.71e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-5)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (9.81e-3)" 0.2 0.0 0.4 0.0 1.3 0.1 0.2 0.9 0.6 0.2 0.6 0.0 0.0 1.3 0.1 0.0 1.2 0.0 0.7 0.9 0.6 0.2 81.6 0.8 0.0 2.3 6.7 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 0.6 0.0 2.3 1.0 0.0 0.1 0.1 0.0 0.1 0.1 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.1 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.9 0.6 0.9 0.6 2.3 6.7 3.9 0.9 1.0 1.3 1.9 3.2 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.8 0.0 0.0 1.6 0.0 2.7 0.0 2.1 0.0 1.4 0.0 0.0 0.0 26.2 4.7 0.2 2.1 0.0 0.0 3.7 0.0 0.0 0.1 0.0 1.7 0.0 0.0 1.8 26.4 0.0 0.0 2.9 0.0 0.0 0.3 0.0 11.0 0.0 0.2 0.0 2.8 0.0 0.0 2.1 8.5 4.6 0.0 0.0 0.4 0.7 0.0 0.0 0.0 24.7 0.6 0.0 0.3 0.4 0.5 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 752.2;choroid plexus: 301.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 66.6 74.3 515.1 10.2 720.1 15.1 26.4 696.9 571.9 15.8 301.8 21.2 25.6 16.5 40.1 15.6 17.3 17.7 43.4 457.6 578.5 110.1 197.2 23.3 11.9 663.0 752.2 18.3 28.8 49.9 32.7 11.8 688.6 28.7 17.0 40.1 36.3 19.5 108.6 16.2 23.9 17.9 524.9 14.3 23.7 12.4 602.6 13.6 22.1 61.2 13.3 14.5 15.1 663.7 33.1 62.5 30.2 35.8 66.1 32.3 41.5 43.2 22.3 47.5 41.6 52.2 46.4 12.2 28.0 30.3 50.8 18.4 40.3 58.4 33.7 35.3 7.3 34.8 33.4 128.3 37.3 46.2 2.9 40.8 35.6 31.6 40.3 25.9 24.5 33.2 37.0 29.0 50.6 19.2 65.0 77.8 44.8 36.7 45.4 27.0 21.0 52.2 48.2 17.5 47.1 64.3 31.9 6.7 156.6 35.0 15.7 19.0 37.7 23.6 41.1 26.5 38.2 43.1 67.7 85.3 52.0 43.1 41.7 0.3 38.9 3.0 31.3 61.3 29.8 18.6 33.1 32.3 48.3 18.3 37.4 32.6 1.1 29.8 48.4 115.1 20.3 34.4 515.1 720.1 696.9 571.9 457.6 578.5 663.0 752.2 688.6 524.9 602.6 663.7 20.3 28.9 31.5 10.7 14.8 20.0 21.3 32.2 18.8 36.2 37.6 28.3 74.4 50.1 19.5 38.6 8.4 69.6 22.8 13.7 109.5 41.1 1.0 11.8 19.1 17.2 174.3 30.1 23.1 23.4 34.2 27.1 27.5 17.8 25.4 42.3 20.7 337.6 80.3 82.4 21.9 31.1 34.6 38.1 23.9 4.8 22.7 32.2 152.9 12.2 23.4 387.2 16.5 15.1 481.3 16.9 11.6 38.0 23.6 23.2 41.4 527.2 6.2 31.4 26.3 27.5 25.4 3.3 58.9 29.7 16.1 18.3 18.5 90.0 35.7 17.3 QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29663279-29698699 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 119.4;liver: 183.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 404.7;Extravillous trophoblasts: 315.1;Hepatocytes: 367.4;Proximal tubular cells: 598.8;Syncytiotrophoblasts: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 4.2;intermediate monocyte: 5.3;myeloid DC: 5.8;non-classical monocyte: 9.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 5.8;monocytes: 9.0" "Cell line enhanced" "Detected in many" "EFO-21: 597.1;Hep G2: 258.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011887, HPA076010" Enhanced Approved Vesicles "Intracellular and membrane" NA NA 780000 "Cluster 7: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA011887: AB_2668555, HPA076010: " "prognostic unfavorable (5.10e-5)" "unprognostic (2.00e-1)" "unprognostic (9.48e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (9.31e-4)" "unprognostic (1.44e-2)" "unprognostic (8.75e-2)" "unprognostic (1.22e-1)" "unprognostic (8.16e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (6.81e-2)" "unprognostic (3.37e-2)" "unprognostic (1.33e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-2)" 8.4 89.4 20.6 4.3 20.2 4.8 6.7 25.8 19.8 50.6 19.4 19.2 61.6 26.1 95.2 4.0 43.6 10.2 26.8 18.5 22.2 119.4 183.5 9.2 6.8 28.6 26.6 31.0 34.5 16.2 5.8 27.3 32.4 7.0 15.2 7.5 13.4 26.1 5.1 5.1 30.3 13.7 23.6 17.2 7.1 4.1 22.8 8.2 6.5 1.2 5.2 10.5 11.5 23.3 0.6 1.4 51.8 56.4 8.8 21.6 167.8 6.0 5.2 8.6 11.0 145.9 91.9 2.3 597.1 10.8 10.0 1.0 18.5 0.6 4.5 0.8 16.7 27.1 2.2 258.0 52.5 4.1 10.4 69.8 1.4 4.8 0.2 12.8 0.2 28.2 75.1 2.9 0.4 154.6 17.6 100.3 162.1 1.9 0.2 89.3 16.3 58.5 47.9 4.2 48.6 103.5 0.0 142.1 118.8 85.1 106.5 112.8 0.6 2.5 24.9 0.9 0.5 1.8 4.9 18.8 4.4 10.4 8.1 0.0 4.2 0.3 0.8 5.3 0.9 0.1 0.6 0.7 5.8 0.0 0.1 0.4 0.8 0.4 9.0 3.1 0.9 1.9 20.6 20.2 25.8 19.8 18.5 22.2 28.6 26.6 32.4 23.6 22.8 23.3 3.1 9.6 24.8 5.2 10.1 3.6 11.7 0.5 1.8 3.3 5.0 2.0 43.2 8.6 3.0 64.4 0.0 404.7 5.8 84.5 50.9 1.2 0.0 93.8 49.5 5.5 28.3 10.5 1.3 55.2 315.1 35.8 0.5 81.0 5.1 6.7 9.7 367.4 147.5 6.7 5.6 47.3 0.0 21.2 18.3 0.5 29.2 19.8 42.7 12.2 4.4 20.8 3.1 11.1 0.5 11.5 78.5 27.1 8.7 4.2 161.0 598.8 1.5 5.0 6.6 3.3 16.2 0.5 3.0 0.2 2.0 215.6 5.7 36.5 104.7 8.3 RAB11A YL8 ENSG00000103769 "RAB11A, member RAS oncogene family" P62491 15 65726054-65891989 "Predicted intracellular proteins" "Cell cycle, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 969.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013097, HPA051697, HPA060686" Approved Enhanced "Vesicles,Centriolar satellite" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Vesicles, Centriolar satellite" "CAB013097: AB_2533987, HPA051697: AB_2732569, HPA060686: AB_2684342" "unprognostic (4.15e-2)" "unprognostic (5.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.74e-3)" "unprognostic (6.85e-2)" "unprognostic (6.07e-2)" "unprognostic (3.17e-2)" "unprognostic (7.12e-2)" "unprognostic (8.60e-2)" "unprognostic (4.83e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (4.29e-2)" "prognostic favorable (1.46e-5)" "unprognostic (9.93e-2)" "unprognostic (1.83e-2)" "unprognostic (5.23e-3)" "unprognostic (1.21e-1)" 140.0 231.6 79.7 123.9 86.4 126.0 150.1 83.4 105.0 159.3 78.5 223.8 139.8 117.4 130.9 480.0 146.1 185.1 156.3 86.1 97.4 162.9 124.1 148.1 141.2 87.0 83.0 104.9 107.6 192.5 106.8 214.4 101.3 150.3 224.2 99.0 195.1 126.2 119.6 288.5 158.9 149.2 87.2 183.9 216.2 201.8 86.0 143.6 155.3 109.6 246.0 269.8 232.2 86.7 285.2 330.3 330.1 240.8 294.7 275.0 431.1 297.0 300.4 264.4 313.0 305.8 497.4 370.7 295.8 342.6 262.3 429.0 525.0 393.2 248.2 243.7 314.9 445.3 219.9 274.1 224.7 211.5 254.0 282.8 438.1 260.2 214.7 281.7 595.2 197.8 364.5 214.3 378.1 283.7 209.9 167.3 275.9 1057.4 185.9 176.3 250.5 346.3 716.1 734.7 237.4 251.9 214.0 335.6 286.5 387.8 445.0 243.0 453.7 208.4 296.4 203.1 267.8 112.2 289.5 288.8 193.7 353.5 228.8 183.5 154.8 235.2 56.7 133.9 58.8 78.8 85.3 68.6 137.1 64.1 78.9 63.6 232.8 71.3 154.6 87.6 109.5 340.2 79.7 86.4 83.4 105.0 86.1 97.4 87.0 83.0 101.3 87.2 86.0 86.7 155.7 57.7 57.8 15.3 90.2 192.2 180.2 375.2 134.3 42.3 107.5 69.6 89.5 105.8 245.4 187.6 33.3 326.4 76.0 313.4 346.3 360.6 413.1 119.3 72.7 260.7 206.2 91.1 31.3 337.0 340.4 96.9 149.9 194.5 74.9 75.9 235.2 88.4 239.2 57.2 27.7 227.4 244.1 114.8 214.2 80.9 97.3 148.1 186.7 42.2 217.8 137.9 65.9 25.6 21.9 391.1 277.0 86.5 72.1 187.6 205.8 271.5 240.0 36.1 46.0 45.2 161.5 407.5 95.3 225.5 284.4 969.3 96.6 97.6 209.2 360.8 RAB14 "FBP, RAB-14" ENSG00000119396 "RAB14, member RAS oncogene family" P61106 9 121178133-121223014 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026419, CAB037066" Approved Supported Vesicles NA NA 2700000 "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB037066: AB_1841128, HPA026419: AB_1855996" "unprognostic (1.30e-3)" "unprognostic (3.12e-2)" "unprognostic (9.01e-2)" "unprognostic (7.18e-2)" "unprognostic (6.53e-2)" "unprognostic (3.00e-1)" "unprognostic (1.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.52e-1)" "unprognostic (6.90e-2)" "unprognostic (3.05e-2)" "unprognostic (9.71e-3)" "prognostic favorable (1.79e-8)" "unprognostic (1.38e-1)" "unprognostic (3.17e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" 39.0 38.7 37.5 35.6 39.7 66.5 42.1 40.3 47.7 37.8 32.6 42.8 39.9 35.6 34.2 63.2 34.0 30.7 32.4 38.4 40.9 50.0 82.8 49.2 41.1 39.6 39.9 35.9 27.6 45.8 28.9 43.1 40.5 38.8 42.4 45.5 34.6 38.1 39.4 56.4 38.9 33.4 40.8 38.3 44.3 33.8 40.2 35.2 43.8 38.9 49.5 43.9 40.8 46.8 53.8 53.7 66.9 56.3 76.2 82.5 52.6 74.8 59.6 56.6 44.7 42.6 57.0 51.2 42.5 72.0 49.2 100.1 48.1 55.8 63.6 44.4 31.7 55.7 69.0 43.9 52.6 60.1 63.8 53.0 98.5 58.2 63.4 62.5 81.2 47.1 42.8 45.6 85.6 50.8 58.5 48.1 39.7 104.8 59.9 45.8 72.3 60.4 62.3 76.0 58.9 34.4 89.0 78.0 53.8 47.1 82.1 46.8 76.0 60.1 43.9 75.3 53.0 40.8 82.6 52.3 56.6 51.9 80.7 34.4 29.4 33.5 22.4 41.5 22.4 24.6 20.9 24.7 31.4 23.4 24.6 25.0 31.8 26.5 43.7 19.0 29.3 24.0 37.5 39.7 40.3 47.7 38.4 40.9 39.6 39.9 40.5 40.8 40.2 46.8 102.6 160.3 103.9 23.5 64.4 157.9 78.2 84.8 97.3 93.8 70.7 58.8 39.2 62.9 96.2 62.5 37.5 85.2 79.6 95.1 86.1 81.3 41.9 80.7 89.8 84.5 60.3 44.4 42.5 64.4 83.0 68.7 64.7 94.4 77.2 58.1 61.1 113.6 91.0 94.2 38.0 59.8 95.6 89.9 105.4 36.2 51.9 80.7 110.3 44.0 84.8 100.5 49.4 38.2 59.0 80.7 52.9 56.4 50.2 81.0 63.2 103.3 86.8 62.0 59.2 64.0 105.6 112.9 113.6 120.0 202.4 116.2 74.3 82.5 64.0 106.0 RAB17 ENSG00000124839 "RAB17, member RAS oncogene family" Q9H0T7 2 237574322-237601614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.7;liver: 107.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Distal tubular cells: 137.0;Hepatocytes: 121.7;Proximal enterocytes: 222.5;Proximal tubular cells: 170.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.4;Hep G2: 39.9;MCF7: 52.0;SK-BR-3: 48.1;SK-MEL-30: 86.7;T-47d: 34.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA035176 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035176: AB_10696368" "unprognostic (8.66e-2)" "unprognostic (1.13e-1)" "unprognostic (1.44e-3)" "unprognostic (9.14e-2)" "unprognostic (2.48e-3)" "unprognostic (1.26e-3)" "unprognostic (1.33e-1)" "unprognostic (5.36e-2)" "unprognostic (3.49e-2)" "unprognostic (2.68e-2)" "prognostic favorable (4.14e-4)" "unprognostic (5.87e-2)" "prognostic favorable (3.33e-13)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (3.44e-1)" "prognostic favorable (2.51e-4)" 0.8 1.0 0.9 1.6 0.6 0.4 15.0 0.6 1.3 6.7 25.8 16.4 76.7 2.3 19.4 2.1 11.1 14.7 1.5 2.2 0.7 49.8 107.6 23.1 0.4 0.8 0.7 0.6 38.7 36.9 3.0 13.8 0.7 7.0 15.6 4.2 34.8 15.3 1.4 0.9 73.7 1.0 0.6 0.5 33.5 0.7 0.9 1.0 33.4 0.0 0.8 3.8 0.3 0.7 9.5 0.3 0.0 17.7 0.1 0.2 42.4 0.2 0.1 0.0 0.1 28.7 26.6 0.0 5.6 0.2 0.1 0.4 0.0 12.5 0.2 0.0 0.0 0.0 0.1 39.9 0.0 0.2 0.0 0.0 7.8 0.0 0.9 0.7 0.0 0.1 0.0 0.0 1.0 52.0 0.0 0.6 0.5 28.6 0.1 1.1 0.0 3.4 13.7 25.1 10.5 0.1 0.0 48.1 86.7 9.4 34.8 0.7 0.0 0.2 0.6 0.1 0.1 0.1 1.2 0.0 0.1 2.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.6 1.3 2.2 0.7 0.8 0.7 0.7 0.6 0.9 0.7 1.2 60.9 34.3 0.3 0.5 1.8 3.4 3.3 22.8 1.7 32.2 18.3 1.0 65.8 11.9 46.0 106.3 16.0 0.1 49.6 137.0 40.0 0.0 18.2 1.6 1.8 30.3 0.0 0.8 28.0 3.8 0.7 29.0 22.1 0.0 0.4 2.5 121.7 1.9 0.0 1.5 23.9 24.4 2.2 0.6 0.7 8.7 1.3 5.4 0.0 0.6 0.2 0.0 1.0 0.1 27.9 50.1 3.8 0.1 5.3 222.5 170.2 13.7 0.6 0.0 0.3 0.7 0.0 0.2 6.6 0.6 12.3 1.3 0.7 21.9 6.5 RAB29 "RAB7L, RAB7L1" ENSG00000117280 "RAB29, member RAS oncogene family" O14966 1 205767986-205775482 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 73.1" "Cell type enhanced" "Detected in many" "dendritic cells: 82.3;monocytes: 76.4;NK-cells: 129.8;Proximal tubular cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020822, HPA026303" Approved Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB020822: , HPA026303: AB_1856016" "unprognostic (5.38e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.82e-5)" "unprognostic (9.50e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.60e-2)" "unprognostic (3.14e-1)" "unprognostic (5.50e-2)" "unprognostic (2.45e-1)" "unprognostic (3.05e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.53e-1)" "unprognostic (8.20e-3)" "unprognostic (1.42e-1)" 13.5 14.4 12.5 20.4 14.1 7.1 14.1 14.3 12.1 8.7 10.5 12.6 10.6 8.3 23.8 7.8 6.2 16.9 13.1 12.3 14.3 73.1 19.4 13.5 35.1 15.9 12.9 7.9 9.2 25.5 5.9 7.2 15.8 13.8 10.1 6.8 19.8 13.9 6.4 5.5 12.4 14.8 14.3 24.3 10.4 4.6 15.3 12.1 33.4 6.0 28.0 15.7 5.7 17.0 20.4 18.6 2.8 13.1 52.5 29.8 9.7 14.1 43.2 28.9 34.4 5.6 28.7 21.6 13.6 24.3 34.6 11.2 32.8 37.3 26.4 88.3 15.3 16.4 7.3 9.5 25.4 16.1 23.2 29.0 24.6 23.3 32.8 24.0 37.2 19.8 16.2 24.2 41.2 7.6 17.7 8.3 13.1 25.4 14.0 3.7 43.1 17.5 33.6 27.7 4.4 12.5 10.0 45.0 37.8 10.3 22.0 13.2 38.7 29.7 15.0 43.5 20.6 39.4 87.0 11.5 30.1 26.3 22.5 92.4 22.6 62.3 92.2 43.8 86.9 50.8 51.0 79.5 33.4 45.8 37.2 63.5 8.8 94.1 53.9 10.4 53.3 51.3 12.5 14.1 14.3 12.1 12.3 14.3 15.9 12.9 15.8 14.3 15.3 17.0 16.3 19.2 17.7 11.1 61.2 0.0 6.3 0.0 13.6 2.1 19.5 16.0 19.3 21.5 6.2 31.3 0.0 12.0 82.3 1.9 29.4 18.7 5.1 2.0 6.3 18.6 4.9 10.8 7.8 10.1 6.4 11.2 10.7 3.5 13.3 9.2 14.6 33.7 32.8 0.0 10.2 3.7 0.0 30.1 0.0 4.1 14.3 34.0 0.0 10.3 76.4 26.5 129.8 10.6 9.8 8.3 4.8 20.7 34.8 10.7 9.5 187.7 2.9 2.0 6.6 10.0 6.7 3.8 11.8 9.3 0.0 2.9 51.7 19.7 5.5 6.9 RAB38 NY-MEL-1 ENSG00000123892 "RAB38, member RAS oncogene family" P57729 11 88113251-88175443 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 48.6;skin 1: 44.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.4;Basal respiratory cells: 74.8;Cytotrophoblasts: 94.5;Melanocytes: 131.6;Suprabasal keratinocytes: 98.5;Syncytiotrophoblasts: 54.7" "Cancer enhanced" "Detected in all" "melanoma: 73.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "NK-cell: 18.0" "Lineage enriched" "Detected in many" 4 "NK-cells: 18.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 87.7;hTCEpi: 308.0;hTERT-HME1: 271.4;SK-MEL-30: 175.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "basal ganglia: 1.1" HPA071701 Uncertain "Nuclear bodies,Mitochondria" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear bodies, Mitochondria" "HPA071701: " "unprognostic (2.85e-1)" "unprognostic (1.30e-1)" "unprognostic (4.40e-2)" "unprognostic (2.66e-2)" "unprognostic (1.36e-2)" "unprognostic (7.95e-2)" "unprognostic (3.96e-4)" "unprognostic (2.36e-1)" "unprognostic (1.44e-1)" "unprognostic (9.34e-2)" "unprognostic (1.00e-2)" "unprognostic (8.23e-2)" "prognostic favorable (8.26e-4)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" 2.6 27.8 0.4 1.4 0.4 1.6 8.6 0.3 0.8 11.8 6.3 1.9 2.4 4.7 6.7 48.6 5.6 6.0 1.1 0.7 0.6 4.5 1.8 5.8 1.7 0.5 0.7 3.3 1.6 1.8 2.8 14.7 0.5 2.4 1.3 2.9 7.7 6.4 0.6 44.3 2.3 3.6 0.4 1.6 1.6 2.5 0.8 3.5 7.9 0.4 17.9 8.7 23.5 0.6 10.7 1.4 0.3 0.5 0.4 2.4 0.6 6.5 26.1 10.4 19.0 4.7 4.8 0.5 6.3 6.9 1.2 71.2 5.7 87.7 14.1 1.3 5.1 54.0 6.2 0.0 1.0 0.6 0.6 2.2 308.0 1.4 271.4 13.0 12.3 1.0 0.3 0.9 0.0 0.0 0.7 18.4 8.2 0.7 0.1 0.5 0.1 0.8 20.0 40.6 1.9 1.2 0.3 0.1 175.6 6.2 15.7 4.6 6.7 0.0 4.6 0.0 1.1 1.5 6.5 0.2 1.7 2.2 1.2 0.0 0.8 0.1 1.5 0.6 0.8 0.0 0.4 1.8 1.6 0.0 0.1 0.8 0.6 18.0 1.3 4.4 1.0 0.7 0.4 0.4 0.3 0.8 0.7 0.6 0.5 0.7 0.5 0.4 0.8 0.6 1.0 0.0 6.7 0.7 0.1 46.4 15.9 74.8 21.1 0.1 6.9 9.7 0.2 8.6 25.0 0.0 0.0 94.5 2.7 0.5 3.9 1.7 0.0 2.1 0.9 2.7 0.0 5.5 0.6 1.1 10.5 9.1 3.1 2.3 16.5 5.3 1.1 0.0 17.5 0.0 0.4 0.3 14.2 1.6 21.2 0.1 3.4 3.9 131.6 3.7 6.3 0.6 1.0 2.0 0.1 2.6 2.6 1.2 0.1 9.5 2.1 5.3 7.4 6.4 0.0 0.6 5.3 0.1 5.9 38.1 98.5 54.7 2.7 5.9 2.5 23.3 RACGAP1 MgcRacGAP ENSG00000161800 "Rac GTPase activating protein 1" Q9H0H5 12 49976923-50033136 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.9;lymphoid tissue: 43.0;testis: 45.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 55.7;Extravillous trophoblasts: 49.4;Spermatocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025859, HPA039427, HPA043912" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB025859: , HPA039427: AB_2676503, HPA043912: AB_2678728" "prognostic unfavorable (1.51e-4)" "unprognostic (1.91e-1)" "unprognostic (3.74e-3)" "unprognostic (1.53e-2)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.86e-6)" "unprognostic (1.15e-3)" "unprognostic (3.07e-3)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.12e-6)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.98e-8)" "unprognostic (3.13e-2)" "unprognostic (4.94e-1)" "unprognostic (6.16e-2)" "unprognostic (2.15e-1)" 5.0 2.5 5.5 13.7 8.2 38.9 7.1 6.9 6.3 5.2 3.2 16.7 10.5 5.3 1.5 21.3 4.4 6.4 2.8 5.0 6.0 9.2 4.7 6.2 23.9 6.7 7.1 2.4 2.7 5.8 1.4 14.0 6.5 3.3 18.7 5.3 4.8 3.4 4.9 14.4 11.6 12.5 5.5 6.5 9.8 45.5 7.6 43.0 3.3 4.8 30.2 7.7 8.0 7.0 193.0 174.5 135.8 86.8 24.8 29.7 113.0 195.0 97.0 207.3 140.3 174.6 144.7 107.5 86.0 108.3 99.9 127.1 137.7 93.6 219.9 203.0 85.4 137.9 165.8 58.1 8.4 146.1 109.0 16.2 17.2 140.7 111.4 60.3 71.7 96.4 101.6 159.6 197.0 136.8 122.5 72.6 96.2 108.9 112.9 113.9 163.5 78.3 54.9 95.7 113.9 97.5 161.7 102.7 53.0 68.8 199.7 64.8 64.9 136.2 119.1 86.8 144.7 83.3 225.2 126.6 67.7 97.0 81.1 24.1 3.2 4.7 6.5 4.1 5.7 8.2 7.9 9.2 2.8 4.3 4.6 6.1 0.7 11.0 2.6 1.8 19.1 5.8 5.5 8.2 6.9 6.3 5.0 6.0 6.7 7.1 6.5 5.5 7.6 7.0 2.0 6.4 6.4 2.9 4.2 12.9 2.5 4.9 6.2 1.5 4.8 5.1 1.5 2.8 3.3 5.5 4.2 21.8 4.4 3.1 19.6 1.9 15.2 2.2 3.1 2.7 0.0 55.7 7.5 2.2 49.4 5.9 7.7 4.0 2.5 14.2 5.3 2.7 13.1 1.7 8.0 5.7 20.3 11.3 8.0 17.7 1.5 7.1 1.8 1.0 4.5 2.7 6.2 6.0 12.3 2.0 1.0 3.8 10.9 2.8 1.1 2.1 2.3 0.8 13.1 3.1 5.5 79.6 32.2 19.5 12.9 8.6 6.9 2.2 11.6 2.9 RAD23B "HHR23B, HR23B, P58" ENSG00000119318 "RAD23 homolog B, nucleotide excision repair protein" P54727 9 107283137-107332192 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 420.5;Late spermatids: 1201.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029718, HPA029720, CAB033868" Enhanced Supported Nucleoplasm,Cytosol No No 5900000 "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "CAB033868: AB_1128418, HPA029718: AB_10600116, HPA029720: AB_10601008" "unprognostic (3.95e-3)" "unprognostic (1.01e-2)" "unprognostic (2.28e-2)" "unprognostic (8.14e-2)" "unprognostic (4.71e-2)" "prognostic unfavorable (2.58e-4)" "unprognostic (2.94e-1)" "prognostic unfavorable (6.71e-4)" "unprognostic (1.34e-1)" "unprognostic (3.72e-1)" "unprognostic (3.31e-2)" "unprognostic (1.20e-1)" "unprognostic (2.94e-3)" "unprognostic (2.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.49e-3)" "unprognostic (1.04e-1)" 73.8 47.8 26.6 44.4 27.0 82.8 48.5 40.4 37.4 42.8 22.0 47.7 41.9 41.9 68.8 63.6 40.9 34.1 48.7 29.0 29.2 44.4 140.8 39.3 39.4 26.9 27.0 37.8 64.5 50.4 30.5 77.7 26.3 48.2 47.7 42.1 38.4 43.5 153.0 64.7 40.6 55.0 22.5 36.2 41.5 59.4 27.7 58.4 42.6 123.5 49.9 67.5 42.8 30.7 132.9 114.9 158.6 102.9 107.5 166.6 179.9 200.6 162.3 172.8 116.9 190.1 140.5 184.8 79.3 218.6 156.4 181.2 221.0 175.9 172.9 126.4 73.0 96.2 112.0 147.6 140.3 174.2 79.3 141.1 161.3 165.3 248.0 136.0 124.3 79.6 158.3 133.6 159.5 215.0 169.6 88.3 170.5 231.2 133.0 125.3 209.6 87.8 149.8 122.1 144.9 98.2 138.8 193.1 125.8 237.5 197.7 70.5 114.3 129.0 127.0 161.6 152.5 91.9 181.2 98.5 138.0 101.7 138.0 0.9 1.1 1.1 1.9 1.2 2.1 1.8 1.1 1.6 1.0 2.1 1.7 1.5 2.9 2.3 0.8 1.1 2.2 0.6 26.6 27.0 40.4 37.4 29.0 29.2 26.9 27.0 26.3 22.5 27.7 30.7 49.7 44.8 40.4 32.3 54.7 195.5 148.1 40.5 79.1 40.5 65.3 36.6 117.4 68.6 42.2 35.0 27.1 269.7 37.1 82.9 50.9 89.2 420.5 69.8 80.8 68.7 101.0 76.1 54.9 77.4 259.7 79.3 60.6 90.8 36.2 83.0 55.6 209.9 99.5 50.5 47.2 83.8 38.7 65.6 131.1 1201.4 75.5 70.7 74.7 38.4 83.7 40.4 39.1 50.3 54.1 81.0 50.5 87.3 89.3 146.0 51.2 95.9 47.6 43.9 78.9 71.6 88.5 45.3 74.7 126.9 240.9 291.8 50.5 91.1 74.9 141.2 RAD51 "BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA" ENSG00000051180 "RAD51 recombinase" Q06609 15 40694774-40732340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.7;testis: 24.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Extravillous trophoblasts: 67.2;Spermatocytes: 53.6;Spermatogonia: 24.8;Syncytiotrophoblasts: 25.3" "Cancer enhanced" "Detected in all" "testis cancer: 19.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010381, HPA039310" Enhanced Supported "Nucleoli rim,Cytosol" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoli rim" Cytosol "CAB010381: AB_2253533, HPA039310: AB_2676434" "prognostic unfavorable (7.94e-4)" "unprognostic (7.20e-3)" "unprognostic (1.22e-1)" "unprognostic (2.72e-2)" "unprognostic (8.23e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-3)" "unprognostic (2.53e-3)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (2.34e-1)" "unprognostic (9.59e-2)" "unprognostic (1.94e-2)" 0.9 0.6 0.4 5.5 0.5 10.5 1.9 1.7 0.7 1.0 0.6 8.3 3.2 1.2 0.4 4.2 0.7 1.3 0.6 0.4 0.5 0.5 1.3 1.1 11.0 0.4 0.3 0.6 1.4 0.5 0.2 6.8 0.5 0.8 9.1 0.3 1.0 0.3 1.0 3.1 4.1 2.4 0.1 2.4 1.8 24.3 0.3 15.7 0.6 0.5 13.3 1.7 1.5 0.5 33.8 16.1 33.4 16.3 4.4 7.8 31.1 54.9 16.5 43.3 43.8 35.4 22.1 20.4 26.8 20.9 18.9 67.7 56.6 22.1 42.3 39.0 22.2 47.7 28.2 30.4 0.4 37.9 28.5 1.7 2.9 30.0 13.5 6.4 22.5 48.5 59.6 55.8 36.6 28.5 54.4 43.6 35.2 69.2 19.0 61.0 49.0 30.7 15.4 45.3 15.4 27.0 23.6 41.4 8.5 39.2 27.0 39.4 9.9 32.8 22.2 48.7 27.2 12.0 65.1 59.8 16.3 78.0 33.5 1.3 0.6 1.7 2.4 1.3 0.6 1.7 2.5 3.2 1.0 1.1 0.6 1.2 1.2 1.8 1.4 0.9 5.9 1.2 0.4 0.5 1.7 0.7 0.4 0.5 0.4 0.3 0.5 0.1 0.3 0.5 0.0 0.0 0.0 0.3 1.9 3.6 1.5 2.0 0.0 0.8 0.1 0.0 0.9 0.0 1.0 0.0 0.0 35.3 1.4 3.0 0.0 0.0 5.7 0.2 0.2 1.0 0.0 16.0 1.6 0.0 67.2 1.3 2.0 0.2 0.0 0.6 2.2 0.2 12.7 0.0 1.2 5.3 2.0 1.6 1.7 5.3 0.6 0.5 0.0 1.0 0.3 0.3 2.1 0.5 0.6 0.1 5.0 0.7 8.2 0.9 1.0 0.0 0.1 0.0 0.0 0.5 0.9 53.6 24.8 3.9 1.6 25.3 1.2 0.1 8.0 2.1 RAD51AP1 PIR51 ENSG00000111247 "RAD51 associated protein 1" Q96B01 12 4538798-4560047 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Meiosis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.9;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in many" "Early spermatids: 33.4;Erythroid cells: 47.8;Extravillous trophoblasts: 34.1;Hofbauer cells: 40.8;Late spermatids: 68.1;Spermatocytes: 35.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051499 Approved Nucleoplasm Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA051499: AB_2681508" "unprognostic (1.03e-1)" "unprognostic (5.44e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (6.30e-2)" "unprognostic (5.25e-3)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.15e-2)" "unprognostic (2.26e-2)" "unprognostic (6.29e-3)" "prognostic unfavorable (1.22e-5)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.44e-15)" "unprognostic (2.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.88e-2)" "unprognostic (3.75e-2)" 0.9 0.8 0.3 4.8 0.4 16.9 2.7 0.4 0.7 0.9 0.3 5.2 5.2 1.2 0.6 3.2 1.0 1.1 0.5 0.3 0.3 0.8 1.8 1.4 8.9 0.4 0.4 0.5 0.4 0.6 0.3 3.8 0.4 1.3 6.5 1.5 1.0 1.0 0.5 3.2 4.8 1.9 0.4 3.4 2.7 6.3 0.4 14.4 1.0 0.6 7.9 1.7 1.3 0.5 37.5 13.0 45.3 22.7 2.7 5.7 53.0 48.2 21.2 52.6 68.9 35.4 35.4 48.6 7.0 10.4 24.7 23.1 31.8 14.5 80.0 38.7 27.0 61.4 21.6 24.8 0.6 56.6 29.9 1.2 1.5 31.6 30.4 7.5 21.4 33.0 39.2 54.4 33.7 13.6 46.5 20.5 110.4 36.3 14.4 46.0 54.3 19.2 16.1 18.3 15.1 16.6 35.9 27.7 11.6 45.5 11.3 32.6 9.5 35.5 36.5 38.8 52.4 7.8 10.0 93.3 13.3 40.0 29.4 0.0 0.5 0.7 0.1 2.3 0.5 3.1 0.4 1.0 0.4 3.4 0.1 0.2 0.0 1.4 2.0 6.9 1.0 0.6 0.3 0.4 0.4 0.7 0.3 0.3 0.4 0.4 0.4 0.4 0.4 0.5 1.4 0.0 0.5 0.7 6.1 5.2 2.3 6.6 1.2 3.1 3.4 5.7 1.4 2.8 4.5 0.0 4.2 20.3 11.3 5.7 0.0 3.0 33.4 3.3 2.9 2.9 2.4 47.8 2.7 2.7 34.1 5.2 6.1 3.6 1.3 22.6 2.5 1.2 40.8 0.0 1.1 6.4 16.2 6.2 5.6 68.1 1.2 10.1 0.0 3.7 6.8 2.7 3.1 0.5 2.4 1.5 0.8 1.5 15.5 1.0 1.2 1.5 0.9 4.8 0.0 2.4 4.2 35.9 25.0 10.0 2.6 4.7 4.6 2.0 14.6 2.7 RAMP2 ENSG00000131477 "Receptor activity modifying protein 2" O60895 17 42758447-42763041 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 1066.8;Endothelial cells: 562.9;Hepatic stellate cells: 344.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 21 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "ASC diff: 120.4;EFO-21: 80.5;HUVEC TERT2: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052020 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA052020: AB_2681697" "unprognostic (8.64e-2)" "unprognostic (2.12e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (6.79e-2)" "unprognostic (1.28e-2)" "unprognostic (6.96e-3)" "unprognostic (4.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" 190.0 29.0 60.4 19.2 61.8 0.1 168.9 61.7 72.3 100.7 67.7 35.7 12.5 63.1 27.8 25.1 51.7 39.6 123.2 59.3 65.8 70.5 16.7 163.3 26.2 65.7 68.1 33.0 17.1 23.8 20.8 97.0 72.7 42.1 21.1 4.1 45.9 27.5 43.3 55.9 44.1 72.6 62.7 40.2 33.9 11.9 66.6 11.4 71.7 98.7 24.5 45.9 49.6 62.4 0.1 1.1 4.9 0.1 120.4 6.2 4.0 0.9 2.1 10.2 4.9 11.5 0.1 0.0 80.5 3.0 0.5 0.0 4.6 0.1 8.9 0.0 0.2 0.0 0.7 3.7 3.0 0.0 0.0 4.2 0.1 1.8 0.4 3.5 37.6 1.5 0.1 0.2 0.6 0.0 0.6 0.8 23.3 0.0 0.0 0.1 0.1 0.0 0.6 0.6 4.8 9.8 2.9 0.0 17.3 4.8 1.2 3.2 6.7 19.3 7.1 0.4 2.4 0.0 0.1 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 60.4 61.8 61.7 72.3 59.3 65.8 65.7 68.1 72.7 62.7 66.6 62.4 1066.8 0.0 5.7 1.6 6.2 34.4 5.4 0.9 9.6 0.6 24.0 24.8 2.2 0.0 1.0 3.7 0.0 1.1 3.7 0.1 3.9 0.6 1.6 22.2 52.8 562.9 4.2 0.0 0.2 0.7 1.7 126.9 3.1 38.5 0.0 1.4 344.8 1.3 3.4 0.0 1.0 0.2 20.3 8.4 40.5 3.6 38.8 4.1 23.2 45.0 2.6 15.5 0.0 1.5 0.3 0.0 0.0 21.8 5.2 4.8 0.0 1.0 0.1 1.8 6.6 10.5 26.3 26.6 59.1 2.6 27.6 1.5 4.0 14.0 0.1 4.3 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RAP1GAP "KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII" ENSG00000076864 "RAP1 GTPase activating protein" P47736 1 21596215-21669363 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 152.4;thyroid gland: 162.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 64.1;Distal tubular cells: 72.4;Excitatory neurons: 82.0;Horizontal cells: 92.5;Intestinal goblet cells: 112.6;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 46.3;OE19: 162.8;SCLC-21H: 52.1" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 231.1" "HPA001922, CAB003851" Enhanced Supported Approved Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "CAB003851: AB_562338, HPA001922: AB_1079743" "unprognostic (1.17e-2)" "unprognostic (4.33e-2)" "unprognostic (7.84e-2)" "unprognostic (2.45e-2)" "unprognostic (4.52e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (8.33e-2)" "unprognostic (1.52e-2)" "unprognostic (2.35e-1)" "unprognostic (3.43e-2)" "unprognostic (1.35e-2)" "prognostic favorable (1.12e-6)" "unprognostic (1.11e-1)" "unprognostic (9.85e-3)" "unprognostic (4.86e-3)" "unprognostic (3.64e-2)" 0.6 80.8 74.0 2.6 118.6 0.8 4.4 24.6 91.9 7.5 0.0 19.7 12.4 1.9 1.9 7.5 4.2 24.9 9.5 76.2 34.5 152.4 36.1 14.2 1.0 35.8 22.0 1.6 106.2 57.1 37.9 2.1 32.8 12.8 17.3 27.3 88.7 0.8 0.2 3.5 21.7 0.7 15.8 1.2 110.8 3.6 32.4 0.5 162.8 0.3 0.9 4.0 3.4 67.3 6.2 46.3 0.5 3.6 0.0 0.0 0.8 0.0 0.1 0.1 0.0 4.3 6.4 0.1 4.6 0.2 30.2 7.9 4.4 0.3 0.1 1.0 2.3 2.2 4.3 22.1 0.7 0.0 6.6 0.3 3.1 0.0 0.0 0.0 0.0 22.1 29.6 1.1 0.0 15.6 7.7 0.7 2.8 162.8 7.0 4.3 1.2 1.1 10.2 3.4 52.1 9.3 7.7 27.4 8.9 1.8 2.7 5.2 0.1 0.0 3.1 0.0 0.1 0.6 0.1 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.0 118.6 24.6 91.9 76.2 34.5 35.8 22.0 32.8 15.8 32.4 67.3 0.0 9.6 29.3 10.4 0.5 1.3 1.1 1.1 0.6 64.1 8.5 5.6 5.1 25.8 4.5 14.7 0.0 0.2 0.1 4.3 72.4 25.1 0.8 3.1 0.6 0.4 6.7 4.0 82.0 28.8 1.4 1.0 17.3 8.0 0.0 6.2 0.4 8.5 0.3 92.5 45.8 112.6 6.1 0.6 0.3 0.3 0.0 0.6 16.0 3.7 0.6 11.5 0.0 51.8 18.6 15.3 17.2 0.0 0.2 5.0 6.0 13.5 1.2 7.3 0.0 0.0 0.7 1.0 3.6 0.5 1.1 1.5 0.3 2.5 7.7 2.6 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 199.1;skin 1: 237.7;vagina: 113.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.7;Excitatory neurons: 47.8;Proximal enterocytes: 55.3;Squamous epithelial cells: 95.4;Suprabasal keratinocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HaCaT: 92.4;hTCEpi: 45.8;T-47d: 80.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: AB_1856071" "prognostic favorable (8.43e-4)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.13e-2)" "unprognostic (4.64e-3)" "unprognostic (3.48e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (8.84e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" 6.3 4.4 38.4 6.8 36.1 4.4 9.1 12.1 58.3 48.7 1.8 53.8 48.3 4.6 9.9 199.1 6.6 8.8 6.8 55.1 12.9 3.8 10.5 8.0 2.2 12.0 11.4 3.7 7.9 1.1 14.2 2.3 10.9 17.7 44.5 6.1 27.4 6.9 12.6 237.7 40.6 4.0 8.3 7.3 31.8 10.2 15.2 3.3 4.5 2.8 20.7 21.9 113.2 30.6 5.3 2.6 13.7 10.2 1.5 3.3 6.6 1.9 1.4 2.7 3.2 6.0 7.6 4.2 1.9 2.7 2.4 92.4 2.7 3.3 3.8 7.7 6.9 2.5 3.6 6.0 1.7 5.2 8.5 3.9 45.8 2.8 1.3 4.0 4.1 13.9 1.9 2.8 2.1 14.6 4.9 6.3 4.3 26.1 2.6 8.8 1.6 2.6 1.7 27.6 26.2 5.3 3.3 31.2 1.3 11.5 80.7 3.9 7.9 3.3 6.8 3.5 3.2 4.6 4.7 3.4 7.8 3.2 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 38.4 36.1 12.1 58.3 55.1 12.9 12.0 11.4 10.9 8.3 15.2 30.6 1.9 0.0 1.1 7.5 1.0 45.5 9.7 14.0 13.1 5.7 2.6 3.7 2.4 11.5 10.9 1.8 6.2 0.2 0.7 87.7 0.0 0.9 2.7 5.9 2.1 2.2 4.9 2.7 47.8 0.8 0.3 1.4 32.6 9.4 5.7 1.7 3.9 4.4 0.5 1.7 32.1 31.9 6.1 1.2 5.2 2.2 3.4 1.9 5.4 1.0 2.4 2.9 1.0 8.0 5.0 1.6 44.6 3.8 0.1 10.9 55.3 0.1 6.5 4.4 0.0 2.1 1.9 12.0 15.0 95.4 97.0 0.7 1.1 1.8 44.1 39.2 RARG "NR1B3, RARC" ENSG00000172819 "Retinoic acid receptor gamma" P13631 12 53210567-53232980 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 141.6;skin 1: 121.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 42.7;Squamous epithelial cells: 69.9;Suprabasal keratinocytes: 55.8;Urothelial cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.8" "Group enriched" "Detected in all" 4 "dendritic cells: 6.7;T-cells: 18.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 101.0;MCF7: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053883 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA053883: AB_2682292" "unprognostic (7.29e-2)" "unprognostic (1.95e-2)" "unprognostic (6.11e-2)" "prognostic unfavorable (3.68e-6)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" "unprognostic (2.28e-1)" "unprognostic (1.08e-2)" "unprognostic (3.54e-3)" "unprognostic (7.21e-3)" "unprognostic (3.78e-3)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (5.41e-3)" "unprognostic (1.98e-2)" "unprognostic (5.94e-3)" "unprognostic (7.41e-2)" 17.4 16.2 10.2 5.7 9.7 3.7 19.4 13.0 10.9 55.0 10.8 22.7 2.5 23.3 6.0 141.6 27.2 15.7 17.3 9.7 9.5 12.5 3.2 15.2 5.9 10.3 10.0 20.5 8.5 7.2 8.7 9.5 9.3 26.9 7.8 3.9 30.6 16.2 6.9 121.4 10.4 13.0 10.0 10.2 14.5 4.8 9.5 5.1 22.6 10.6 22.5 26.2 69.3 10.0 22.8 24.7 5.5 50.9 55.0 46.8 1.7 23.2 50.0 29.7 23.3 8.3 101.0 0.5 12.5 93.6 16.2 74.3 18.4 44.6 7.4 5.7 9.4 3.3 18.6 7.4 23.2 0.0 9.1 34.8 63.9 28.5 6.4 74.7 12.7 4.6 0.8 9.8 11.9 110.3 1.3 1.1 16.3 30.4 42.7 7.3 1.9 18.1 8.9 37.1 4.4 22.9 47.0 50.6 32.1 6.8 43.9 1.4 13.8 35.4 16.5 23.6 1.5 4.2 2.6 1.8 43.4 3.8 51.3 1.8 3.1 0.9 7.4 0.9 18.8 2.0 6.5 5.4 6.7 0.6 5.2 4.7 0.0 2.3 0.0 0.6 1.8 4.0 10.2 9.7 13.0 10.9 9.7 9.5 10.3 10.0 9.3 10.0 9.5 10.0 10.7 3.2 7.0 21.2 2.5 34.2 24.1 21.6 42.7 0.5 18.0 15.6 3.7 11.5 11.1 3.7 2.1 7.5 6.2 3.2 0.0 10.5 0.1 3.6 14.4 11.0 1.8 0.8 2.5 5.1 1.2 19.6 13.7 3.4 1.3 0.3 20.3 0.1 2.7 0.0 3.0 2.1 12.2 4.1 13.3 0.5 5.3 4.9 8.8 6.5 1.8 3.6 5.2 7.1 0.7 14.3 4.4 5.3 3.0 19.2 0.2 0.5 3.9 5.2 6.6 9.5 22.0 0.8 5.6 69.9 55.8 1.8 7.2 0.4 5.5 45.7 RASEF "FLJ31614, RAB45" ENSG00000165105 "RAS and EF-hand domain containing" Q8IZ41 9 82979590-83063177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 41.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 101.7;Gastric mucus-secreting cells: 356.8;Prostatic glandular cells: 106.4;Respiratory ciliated cells: 100.6;Urothelial cells: 107.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 53.2;RT4: 38.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021431, HPA078596" Approved Uncertain Microtubules NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Microtubules "HPA021431: AB_1856087, HPA078596: " "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.26e-1)" "unprognostic (2.59e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-3)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (8.60e-2)" "unprognostic (1.66e-3)" "unprognostic (3.67e-1)" "unprognostic (1.41e-3)" "unprognostic (5.07e-2)" "unprognostic (6.05e-3)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" 1.1 1.6 16.2 2.8 15.4 3.6 17.6 21.2 21.9 2.9 18.0 15.2 6.3 2.7 10.2 7.1 6.3 12.6 1.1 13.9 9.2 5.3 2.4 8.2 1.5 10.0 6.3 1.5 23.1 5.3 3.9 3.4 9.8 15.2 15.2 5.1 15.3 3.8 1.9 3.8 8.6 1.1 1.0 1.5 41.0 4.0 9.8 3.4 25.9 0.0 3.5 13.8 2.3 24.7 14.0 15.5 1.8 1.5 0.3 0.5 5.6 1.0 0.2 1.6 3.9 8.7 16.9 2.3 13.7 0.4 11.0 16.3 0.3 0.4 1.9 1.4 17.3 1.9 11.9 2.2 0.2 1.7 1.6 0.3 6.7 7.6 0.2 2.1 0.1 2.4 2.5 16.8 0.2 27.2 2.3 1.8 10.5 53.2 6.1 2.5 4.8 6.0 18.0 38.5 5.6 8.3 2.8 26.8 1.1 6.7 22.9 2.0 2.6 2.6 14.6 2.1 1.7 11.3 10.1 1.4 5.8 1.0 3.0 6.5 2.0 1.9 3.7 1.4 3.5 3.9 3.5 2.9 1.1 5.3 3.8 3.3 9.8 3.6 1.6 3.8 2.9 0.7 16.2 15.4 21.2 21.9 13.9 9.2 10.0 6.3 9.8 1.0 9.8 24.7 0.7 76.9 101.7 0.3 1.1 0.8 5.4 7.9 4.0 1.1 61.3 21.1 0.6 42.9 59.7 9.2 4.2 5.5 0.5 61.8 7.9 35.4 0.6 39.7 7.9 4.5 3.6 0.8 1.0 37.4 10.3 5.7 356.8 88.2 22.1 0.4 0.7 1.7 0.8 0.0 0.6 85.7 48.8 0.0 0.4 2.1 0.3 4.2 1.8 4.7 1.6 0.1 0.0 0.0 0.2 46.2 40.0 0.0 1.5 106.4 10.4 8.3 100.6 1.3 0.0 0.7 2.8 0.5 4.8 28.2 0.9 7.5 3.1 1.2 35.7 107.7 RBL1 "cp107, p107, PRB1" ENSG00000080839 "RB transcriptional corepressor like 1" P28749 20 36996349-37095997 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.3;Inhibitory neurons: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054962, HPA056525" Enhanced Enhanced Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA054962: AB_2682652, HPA056525: AB_2683165" "unprognostic (1.97e-1)" "unprognostic (2.47e-2)" "unprognostic (1.30e-2)" "unprognostic (3.70e-3)" "unprognostic (2.13e-1)" "unprognostic (1.51e-1)" "unprognostic (6.25e-5)" "unprognostic (6.91e-2)" "unprognostic (7.19e-3)" "unprognostic (1.20e-1)" "unprognostic (4.49e-3)" "unprognostic (3.23e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (3.15e-2)" "unprognostic (2.75e-1)" "unprognostic (1.47e-2)" "unprognostic (1.26e-1)" 2.0 1.6 1.2 4.8 2.6 14.5 2.8 8.3 1.8 2.3 0.7 2.8 2.4 2.8 1.3 2.9 1.9 2.0 1.8 1.0 1.9 1.6 1.4 2.2 7.3 2.0 1.9 4.4 2.4 2.6 1.1 3.4 2.2 2.0 3.5 4.0 1.5 1.4 6.9 3.1 2.5 2.8 1.4 3.4 2.7 3.1 2.0 8.8 2.7 7.9 6.7 2.0 2.2 3.4 24.8 15.8 19.4 13.1 4.9 6.4 12.4 28.2 12.6 23.9 24.6 16.8 13.5 27.5 7.9 11.8 14.0 23.8 17.5 18.2 39.7 9.7 9.4 27.2 18.1 14.3 3.0 35.3 18.2 3.0 2.5 31.6 11.1 4.0 13.6 17.9 20.1 25.8 13.7 10.5 33.1 11.7 5.7 12.5 15.3 21.3 57.7 20.9 5.5 12.2 4.6 11.5 30.8 17.6 8.2 6.2 11.3 25.3 9.1 42.0 15.9 38.9 24.8 8.6 16.4 27.7 30.2 24.4 21.1 0.9 0.7 1.4 2.7 0.8 2.3 3.0 3.0 2.5 1.3 2.1 3.2 2.7 0.3 2.2 1.2 3.0 4.5 0.9 1.2 2.6 8.3 1.8 1.0 1.9 2.0 1.9 2.2 1.4 2.0 3.4 3.5 6.4 11.0 10.4 8.7 2.4 1.5 1.7 4.0 5.9 2.5 1.7 2.9 1.5 6.1 0.0 2.1 5.9 6.5 1.8 0.0 1.8 1.5 2.2 4.3 3.3 1.2 23.3 14.7 1.1 5.1 4.6 2.6 2.9 8.8 9.0 2.2 1.4 4.5 3.3 22.8 1.9 0.0 3.0 3.2 0.6 2.1 6.8 1.8 6.5 4.7 3.1 7.2 19.6 18.5 0.9 3.6 3.0 14.1 0.8 1.0 0.7 0.9 12.2 6.6 8.5 4.1 17.5 8.7 5.3 1.3 3.8 11.7 6.4 3.5 0.9 RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 442.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 136.2" "Group enriched" "Detected in many" 12 "dendritic cells: 34.4;granulocytes: 136.2;monocytes: 45.5" "Cell line enhanced" "Detected in many" "BEWO: 134.0;CAPAN-2: 63.5;OE19: 56.7;SK-BR-3: 58.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA006347: AB_2181208" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.49e-3)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-2)" "unprognostic (7.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (9.42e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-16)" "unprognostic (1.62e-2)" "unprognostic (9.81e-2)" "unprognostic (1.72e-1)" "unprognostic (5.77e-2)" 9.3 49.7 2.2 20.3 1.9 9.6 24.7 1.8 3.0 15.3 44.9 61.0 68.4 3.5 23.1 42.2 17.7 17.9 1.3 2.8 2.3 67.6 34.5 21.0 8.2 6.0 3.2 2.2 25.9 27.8 3.2 20.1 4.9 33.2 50.5 0.4 59.4 13.4 0.5 9.0 64.1 4.7 4.1 14.7 64.6 6.7 5.7 4.4 49.5 1.1 11.4 22.6 15.5 6.8 31.9 47.8 0.0 1.8 0.2 0.0 134.0 0.8 1.6 0.1 0.6 28.3 63.5 0.2 23.0 1.2 3.8 14.2 0.9 11.8 0.3 0.2 7.6 0.0 3.1 7.9 0.6 0.3 0.3 0.8 6.0 0.1 0.1 1.8 0.0 0.0 1.8 7.0 0.1 18.1 0.2 1.1 13.5 56.7 2.4 0.2 0.0 34.7 46.8 41.6 1.6 0.3 17.3 58.4 0.3 14.8 23.9 9.0 0.0 0.5 1.9 0.3 1.0 23.5 37.7 4.1 5.0 3.9 0.2 0.5 45.5 0.5 0.2 33.1 0.3 5.9 0.2 0.1 34.4 5.4 0.4 0.1 136.2 0.5 26.2 14.1 0.2 16.9 2.2 1.9 1.8 3.0 2.8 2.3 6.0 3.2 4.9 4.1 5.7 6.8 1.1 80.1 116.6 0.7 21.2 58.9 75.2 42.9 95.0 0.1 145.7 63.5 1.9 75.8 92.2 112.2 0.0 99.6 16.3 442.8 64.6 90.6 1.3 132.6 9.5 6.0 121.9 2.5 2.5 115.4 84.3 7.7 174.8 143.7 7.0 8.7 23.6 140.4 92.6 1.7 1.9 234.2 59.0 138.8 92.8 2.6 2.5 119.9 37.4 82.4 80.6 0.3 1.0 2.5 0.8 108.0 228.1 1.2 40.1 164.7 218.1 143.6 118.3 0.1 0.0 1.4 5.1 2.6 10.4 178.1 75.4 262.6 4.8 16.9 203.8 295.4 RBP5 CRBPIII ENSG00000139194 "Retinol binding protein 5" P82980 12 7115736-7128889 "Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 443.5;liver: 324.2" "Cell type enriched" "Detected in many" 8 "Proximal tubular cells: 3197.2" "Group enriched" "Detected in all" 8 "liver cancer: 70.1;renal cancer: 126.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.0;Hep G2: 13.4;K-562: 26.3" HPA038723 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Vesicles "HPA038723: AB_2676175" "unprognostic (5.70e-3)" "unprognostic (7.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.53e-2)" "unprognostic (1.87e-2)" "unprognostic (1.39e-3)" "unprognostic (2.49e-2)" "prognostic favorable (8.37e-4)" "unprognostic (1.04e-1)" "unprognostic (2.65e-1)" "unprognostic (1.13e-2)" "unprognostic (1.13e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-2)" "unprognostic (3.33e-2)" "unprognostic (4.22e-1)" "prognostic favorable (3.68e-4)" 6.4 11.7 0.0 15.0 0.1 1.6 5.1 0.3 0.3 11.2 0.2 8.5 4.6 8.6 3.2 3.8 8.1 5.9 1.4 0.0 0.0 443.5 324.2 3.8 31.2 0.5 0.3 4.9 5.2 1.3 6.2 0.3 0.3 10.0 4.9 0.8 3.7 5.0 0.7 2.4 20.6 5.4 0.0 97.1 5.2 2.2 0.2 14.2 7.9 0.0 21.4 7.4 4.6 0.0 0.9 1.3 0.0 0.3 0.0 0.0 0.2 1.1 0.0 0.0 0.2 1.1 1.2 1.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 1.6 0.0 6.0 3.9 13.4 0.0 0.2 0.9 0.2 0.0 0.0 0.0 2.4 0.0 0.6 26.3 0.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.1 0.1 1.2 0.0 0.2 1.4 0.9 0.0 0.6 0.5 0.7 0.7 0.6 0.5 2.8 0.4 0.3 0.1 0.0 0.3 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.5 0.3 0.3 0.0 0.2 0.0 4.9 0.0 0.6 0.7 15.2 1.5 0.5 0.1 0.0 1.2 1.3 1.3 0.1 5.7 0.1 80.9 0.0 0.1 0.3 0.1 352.1 0.2 4.1 0.3 1.7 28.8 0.0 0.0 2.1 0.4 0.0 8.2 0.0 0.5 0.0 0.2 8.9 361.1 0.1 5.0 1.1 0.0 0.0 8.1 2.6 6.7 2.5 16.6 0.0 1.9 0.0 1.4 0.0 0.5 0.1 0.2 0.0 0.4 0.1 0.5 0.0 3197.2 0.9 1.7 0.0 0.1 4.3 0.7 0.4 0.2 2.3 0.0 7.3 2.4 0.1 0.3 RBPMS HERMES ENSG00000157110 "RNA binding protein, mRNA processing factor" Q93062 8 30384511-30572256 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 324.1;RPTEC TERT1: 232.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056999 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA056999: AB_2683306" "unprognostic (1.65e-1)" "unprognostic (7.81e-2)" "unprognostic (1.53e-1)" "unprognostic (2.23e-3)" "unprognostic (8.66e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-2)" "unprognostic (3.47e-3)" "unprognostic (4.63e-2)" "unprognostic (2.32e-1)" "unprognostic (4.67e-2)" "unprognostic (2.88e-2)" "unprognostic (1.76e-2)" "unprognostic (4.76e-2)" "unprognostic (2.52e-1)" "unprognostic (4.91e-2)" "unprognostic (2.16e-3)" 238.3 96.7 22.3 43.8 28.0 1.4 194.8 20.2 24.1 196.9 26.7 350.6 25.2 200.7 90.0 99.9 200.5 95.4 174.7 17.3 25.2 218.7 108.9 119.6 23.3 23.1 27.6 190.0 68.8 68.6 33.0 105.0 28.7 182.6 46.6 10.4 92.1 193.7 31.2 56.6 107.7 171.9 18.7 56.7 159.8 45.4 33.2 23.5 140.7 31.6 20.0 323.4 134.0 18.9 0.7 54.5 58.5 0.4 324.1 96.4 145.8 74.8 101.8 90.2 74.6 76.2 31.2 0.5 39.3 96.7 82.5 29.9 68.0 54.4 107.9 0.1 14.6 1.8 24.7 80.5 139.4 0.5 12.0 112.8 13.8 86.7 11.5 100.8 52.8 2.5 0.5 0.4 44.6 32.6 0.3 1.2 150.9 62.3 34.6 3.5 16.2 4.7 232.2 88.9 1.1 11.6 7.7 55.2 37.7 192.3 11.7 0.0 48.8 44.3 4.2 77.3 12.8 0.1 0.2 0.4 72.8 0.2 20.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 22.3 28.0 20.2 24.1 17.3 25.2 23.1 27.6 28.7 18.7 33.2 18.9 104.0 54.5 98.9 36.6 4.5 9.3 61.8 22.7 14.2 6.7 45.8 64.3 114.4 75.8 48.5 141.6 2.1 108.7 4.1 1.8 113.5 100.0 104.7 31.2 86.3 69.7 1.8 5.0 6.4 94.8 184.8 66.7 18.8 48.2 10.1 18.0 44.3 55.2 39.9 0.0 5.2 0.1 20.3 1.9 10.2 31.5 171.2 4.3 14.2 71.2 2.1 1.0 1.0 2.0 1.6 67.0 0.0 180.2 0.5 101.5 2.0 242.2 30.9 5.7 111.7 6.6 149.9 35.3 22.0 27.8 8.0 41.2 4.4 28.1 1.0 151.7 RCAN2 "DSCR1L1, ZAKI-4" ENSG00000172348 "Regulator of calcineurin 2" Q14206 6 46220736-46491972 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 199.5;tongue: 180.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 255.4;Excitatory neurons: 261.4;Inhibitory neurons: 254.4;Muller glia cells: 183.1;Oligodendrocytes: 294.6;Smooth muscle cells: 138.4" "Cancer enhanced" "Detected in all" "renal cancer: 25.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "gdT-cell: 1.8;memory CD4 T-cell: 1.1;memory CD8 T-cell: 2.2;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 23 "T-cells: 2.2" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 63.3;HDLM-2: 129.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053880 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA053880: AB_2682290" "unprognostic (2.82e-1)" "unprognostic (7.76e-2)" "unprognostic (4.13e-2)" "unprognostic (1.14e-1)" "unprognostic (5.55e-3)" "unprognostic (4.52e-2)" "unprognostic (1.29e-3)" "unprognostic (1.86e-3)" "unprognostic (2.26e-1)" "unprognostic (4.33e-1)" "prognostic favorable (2.48e-4)" "unprognostic (1.37e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (2.11e-2)" 38.1 12.6 35.7 7.7 41.2 0.0 17.1 31.7 106.3 20.3 0.0 20.1 9.8 17.5 51.5 25.9 17.0 35.1 199.5 34.0 65.0 32.4 4.9 16.3 4.1 69.6 76.0 24.0 11.1 85.5 17.5 0.6 68.8 25.3 22.6 61.6 9.6 27.0 73.3 17.2 19.1 14.0 20.6 7.1 36.5 5.7 65.5 4.7 20.1 180.1 7.0 44.0 21.4 62.3 0.0 0.0 1.6 0.0 0.7 0.2 0.1 1.1 15.1 1.1 0.1 0.0 0.0 0.0 0.8 63.3 0.0 0.1 0.0 0.0 0.3 129.7 0.8 0.0 0.0 0.0 1.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.1 5.1 0.0 0.0 0.2 2.7 0.4 0.4 0.4 13.6 0.1 0.2 0.3 4.9 0.0 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.1 1.8 0.1 0.2 6.8 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.1 2.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 35.7 41.2 31.7 106.3 34.0 65.0 69.6 76.0 68.8 20.6 65.5 62.3 7.6 6.4 5.8 13.7 0.6 6.2 4.6 0.0 0.0 24.8 1.8 1.4 255.4 8.6 0.0 3.7 4.2 0.1 0.8 1.0 70.5 5.5 40.2 0.8 0.4 17.1 25.1 0.0 261.4 2.5 0.0 22.2 1.5 0.8 0.0 0.3 0.4 1.2 0.1 30.3 254.4 1.5 34.6 0.3 8.0 14.2 29.2 0.9 32.0 46.9 0.0 183.1 0.0 76.9 294.6 2.9 0.3 50.4 0.4 3.3 0.0 1.9 0.0 9.7 98.6 16.4 138.4 1.5 1.4 0.5 7.4 0.0 4.0 0.8 0.3 1.4 RCC2 TD-60 ENSG00000179051 "Regulator of chromosome condensation 2" Q9P258 1 17406760-17439677 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072281 Approved NA NA 110000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA072281: AB_2686505" "unprognostic (2.50e-2)" "prognostic favorable (3.31e-4)" "unprognostic (9.91e-2)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (3.42e-8)" "unprognostic (3.05e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (1.73e-1)" "unprognostic (1.31e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (4.03e-8)" "unprognostic (6.81e-3)" "unprognostic (2.09e-1)" "unprognostic (9.44e-2)" "unprognostic (4.41e-2)" 19.4 18.4 12.3 18.9 12.2 33.3 22.2 12.8 13.2 24.8 11.0 24.0 11.4 18.7 9.9 65.2 16.3 11.8 13.4 12.1 12.5 22.8 15.9 24.2 27.7 14.2 13.6 22.1 21.3 9.4 11.4 16.1 13.1 22.3 17.6 3.1 36.0 7.8 8.4 56.3 27.6 10.2 13.9 39.2 18.3 20.6 15.8 34.2 19.0 4.1 35.2 19.7 31.3 15.3 62.2 34.3 68.4 57.9 25.3 25.4 56.6 24.3 20.9 49.2 40.4 37.0 83.4 133.8 80.4 25.3 14.5 67.4 121.0 70.0 34.1 64.3 61.1 117.6 50.5 36.0 31.8 142.7 79.7 40.5 51.8 55.1 48.7 30.7 53.3 88.7 82.4 188.4 22.0 62.9 117.4 115.9 94.7 76.0 26.0 155.7 68.6 86.5 37.3 29.0 102.9 72.6 61.4 59.5 93.6 56.7 53.2 91.3 41.9 44.8 56.0 18.1 51.1 81.7 72.9 165.8 19.3 158.6 90.9 0.9 1.9 0.7 1.4 2.6 1.2 1.6 1.1 1.4 3.1 1.7 0.8 1.4 0.1 1.7 2.1 2.5 1.0 1.1 12.3 12.2 12.8 13.2 12.1 12.5 14.2 13.6 13.1 13.9 15.8 15.3 22.6 25.6 15.3 16.6 26.4 46.5 14.7 25.3 27.9 6.6 36.5 34.3 0.9 18.6 26.6 22.0 10.4 25.0 32.2 27.5 3.9 24.4 6.8 28.0 38.3 24.9 24.1 28.8 11.0 22.7 48.9 17.4 14.8 37.5 17.7 55.9 17.5 7.3 32.6 6.7 4.9 25.9 24.4 31.4 70.0 21.0 9.3 43.0 16.0 20.6 27.9 15.3 22.6 20.6 15.3 28.8 20.6 6.0 25.9 32.2 7.5 7.0 17.9 5.4 0.0 20.7 16.7 17.6 21.2 42.9 64.5 16.3 19.7 25.6 36.4 19.4 REEP1 "C2orf23, FLJ13110, SPG31, Yip2a" ENSG00000068615 "Receptor accessory protein 1" Q9H902 2 86213993-86338083 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 95.5;Oligodendrocyte precursor cells: 39.2" "Cancer enhanced" "Detected in many" "glioma: 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 68.1;HAP1: 15.0;RPMI-8226: 16.0;SCLC-21H: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058061 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA058061: AB_2683591" "unprognostic (1.94e-2)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.29e-2)" "unprognostic (5.10e-2)" "unprognostic (6.63e-2)" "unprognostic (9.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (6.15e-2)" "unprognostic (2.35e-1)" "unprognostic (2.56e-2)" "unprognostic (6.77e-2)" "unprognostic (2.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.07e-3)" 4.7 6.2 17.0 1.8 15.8 0.0 4.9 4.1 30.4 3.9 11.5 42.4 4.4 18.9 3.7 6.2 13.6 3.8 16.6 15.4 44.0 2.0 1.1 3.6 0.5 24.6 38.1 1.9 9.9 7.9 13.9 2.2 50.0 7.3 5.0 12.9 1.6 12.9 19.8 2.0 9.3 20.7 4.4 2.0 8.8 44.5 18.7 0.3 2.0 14.3 0.6 21.7 5.8 14.3 0.0 0.0 2.2 2.9 0.1 0.0 68.1 0.0 0.0 4.5 0.5 2.5 0.0 0.0 3.2 0.0 3.4 4.9 15.0 0.1 3.9 0.0 8.1 0.0 5.0 0.4 0.0 0.3 0.4 0.7 0.1 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.1 2.7 0.1 0.0 2.6 0.1 0.0 0.1 6.5 16.0 0.3 0.3 32.0 3.1 3.5 1.6 0.2 1.3 5.1 0.9 0.0 0.0 2.3 1.3 6.3 7.2 5.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 15.8 4.1 30.4 15.4 44.0 24.6 38.1 50.0 4.4 18.7 14.3 1.7 9.6 0.5 14.7 0.2 2.0 0.3 0.3 0.0 10.0 3.6 1.1 23.0 2.8 2.8 0.0 2.1 2.4 0.0 0.4 1.9 3.5 18.0 17.1 0.3 5.7 4.8 0.0 86.2 6.2 26.6 2.4 0.0 0.7 0.0 0.8 12.5 0.2 0.9 3.3 95.5 0.2 8.2 0.8 1.6 14.4 2.5 0.4 1.8 6.5 0.6 13.4 0.0 39.2 6.0 6.5 0.0 3.4 0.0 1.6 0.0 5.1 16.6 15.8 19.7 4.2 13.5 4.0 2.7 0.5 1.1 6.6 0.2 0.0 0.5 0.4 REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 217.5;liver: 398.0;testis: 283.9" "Cell type enhanced" "Detected in many" "Early spermatids: 559.1;Late spermatids: 3135.0;Proximal enterocytes: 898.7" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 57.9;Hep G2: 56.2;K-562: 155.7;T-47d: 121.4" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" 8.4 86.5 11.1 1.3 12.4 1.2 17.5 10.1 18.0 5.6 7.7 3.0 217.5 3.5 14.6 14.3 4.6 7.0 3.9 12.7 8.8 22.1 398.0 1.6 1.3 9.7 10.1 7.7 28.5 2.0 9.8 1.6 9.9 20.1 1.7 94.0 17.9 6.8 2.0 9.3 199.6 0.9 8.4 1.7 4.2 283.9 12.1 0.7 6.0 0.7 1.0 9.2 7.0 10.9 7.3 9.2 2.6 34.3 5.6 2.0 39.5 1.8 0.7 1.9 1.9 57.9 22.5 3.9 12.2 1.1 2.3 7.3 9.8 0.6 1.0 1.9 4.1 21.3 1.3 56.2 4.2 1.6 6.6 4.7 4.1 0.4 1.4 3.2 1.1 4.9 155.7 5.0 0.3 29.6 1.8 4.7 12.8 21.1 19.5 4.9 1.1 10.0 10.9 2.7 0.7 17.2 9.8 14.2 6.3 1.9 121.4 5.7 3.4 2.8 5.4 8.7 1.2 16.4 5.3 0.8 11.2 9.4 8.2 0.0 1.1 0.0 5.5 1.2 2.8 0.1 1.4 1.2 1.9 0.6 2.0 2.2 0.0 4.9 4.3 3.3 1.6 1.6 11.1 12.4 10.1 18.0 12.7 8.8 9.7 10.1 9.9 8.4 12.1 10.9 1.5 3.2 3.2 2.6 2.7 6.8 7.9 6.8 10.8 30.4 47.4 20.3 1.8 91.5 10.5 5.5 33.3 69.4 2.5 7.8 7.9 34.5 559.1 4.5 7.1 4.2 6.0 10.1 1.5 69.2 12.8 4.7 2.6 3.0 10.2 132.9 5.0 267.4 9.6 23.5 1.2 51.9 4.1 6.3 4.3 3135.0 34.2 4.1 30.2 0.0 1.7 44.2 2.1 0.0 1.5 25.0 53.6 16.6 1.9 13.1 898.7 52.0 8.3 292.8 19.7 0.8 3.3 29.9 36.5 17.5 6.7 36.0 4.3 50.1 70.7 14.7 RELCH "FLJ33841, HsT3308, HsT885, KIAA1468" ENSG00000134444 "RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing" Q9P260 18 62187255-62310249 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Cardiomyocytes: 9.4;Cytotrophoblasts: 6.5;dendritic cells: 8.2;Extravillous trophoblasts: 4.4;Hofbauer cells: 7.2;Plasma cells: 5.2;Syncytiotrophoblasts: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039708, HPA040038" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Centriolar satellite, Cytosol" "HPA039708: AB_10794753, HPA040038: AB_10793860" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (4.03e-2)" "unprognostic (1.98e-3)" "unprognostic (2.44e-2)" "unprognostic (6.30e-2)" "unprognostic (3.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.36e-1)" "unprognostic (4.84e-3)" "unprognostic (2.47e-2)" "unprognostic (6.86e-2)" "unprognostic (3.54e-1)" "unprognostic (1.71e-2)" 8.3 8.8 8.7 9.6 10.8 14.2 11.9 11.1 10.0 11.8 7.2 11.5 9.5 8.5 11.8 25.4 7.7 7.9 7.5 9.7 9.3 9.6 7.9 8.0 11.8 7.9 7.6 8.2 8.3 10.3 11.0 8.1 8.2 12.1 14.4 16.3 12.5 8.8 6.8 20.6 10.8 6.2 7.6 11.2 12.7 5.3 8.8 10.8 9.5 5.9 13.2 10.0 16.2 9.4 9.7 8.7 10.4 10.0 10.8 12.7 11.1 17.0 14.1 15.0 16.5 4.5 8.8 6.6 8.6 15.1 9.8 19.7 14.9 10.2 18.3 6.0 9.3 5.6 9.7 10.4 9.6 10.8 7.4 9.4 12.3 12.8 7.8 12.3 10.3 6.2 4.2 6.5 15.9 5.7 6.7 9.3 6.0 6.5 7.3 8.2 13.0 7.9 17.1 19.1 14.7 7.8 10.2 14.9 8.9 13.4 7.7 11.6 12.9 15.9 5.0 6.9 8.6 19.0 3.7 6.4 11.2 11.4 13.0 1.4 1.0 1.2 1.1 0.8 0.8 0.8 1.0 1.0 1.0 0.9 1.1 1.3 1.7 1.1 0.7 0.7 1.3 0.6 8.7 10.8 11.1 10.0 9.7 9.3 7.9 7.6 8.2 7.6 8.8 9.4 7.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 6.5 8.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 4.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 6.6 1.1 0.0 0.0 0.0 REPS1 ENSG00000135597 "RALBP1 associated Eps domain containing 1" Q96D71 6 138903493-138988261 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 207.3;Excitatory neurons: 114.3;Inhibitory neurons: 138.1;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029961, HPA029962" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane, Cytosol" "HPA029961: AB_10603233, HPA029962: AB_2673269" "unprognostic (1.72e-3)" "unprognostic (9.61e-2)" "unprognostic (5.82e-3)" "unprognostic (2.77e-2)" "unprognostic (6.30e-3)" "unprognostic (1.90e-1)" "prognostic unfavorable (9.47e-4)" "unprognostic (3.79e-1)" "unprognostic (2.49e-1)" "unprognostic (9.71e-3)" "unprognostic (4.29e-3)" "unprognostic (4.42e-2)" "unprognostic (2.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.27e-1)" "unprognostic (3.83e-2)" "unprognostic (2.69e-2)" 13.5 11.9 24.7 14.9 25.4 23.2 23.6 27.7 36.8 19.2 14.8 17.4 15.4 21.9 40.2 28.0 18.4 14.0 23.9 27.4 24.0 17.4 31.3 15.2 19.4 25.2 23.9 21.1 18.8 41.0 31.7 17.2 21.3 15.9 17.3 38.8 26.1 16.2 17.5 30.0 16.4 19.5 21.5 22.1 18.1 35.6 25.9 36.0 17.8 12.6 22.2 19.5 20.1 25.3 29.3 22.6 42.3 53.1 23.4 41.6 46.2 27.8 30.7 31.9 38.2 54.1 24.8 35.2 22.9 38.9 38.0 33.6 48.7 42.0 42.1 37.6 41.9 29.6 12.9 32.9 35.3 94.6 45.9 34.1 33.7 58.6 70.3 30.2 33.5 51.2 40.2 35.1 41.4 49.4 53.9 51.3 40.4 37.4 21.3 62.4 26.0 20.0 26.5 43.6 37.7 37.2 25.7 38.7 38.0 62.0 18.6 64.4 32.9 17.8 29.6 48.5 38.8 34.4 33.7 49.2 21.1 38.3 26.4 5.9 1.3 1.9 2.2 4.0 3.8 3.0 2.9 3.2 1.9 1.6 2.9 3.6 0.7 2.9 4.5 3.5 3.3 1.2 24.7 25.4 27.7 36.8 27.4 24.0 25.2 23.9 21.3 21.5 25.9 25.3 11.8 19.2 7.4 207.3 18.0 13.4 11.7 7.9 22.2 12.6 13.7 9.5 28.4 10.0 12.2 5.5 16.7 25.6 18.9 11.9 7.9 7.8 13.7 17.5 9.7 10.3 6.0 5.0 114.3 7.1 28.3 11.5 16.3 23.3 15.9 14.4 15.7 43.8 13.3 13.5 138.1 12.8 6.1 24.0 10.3 7.7 7.2 17.2 5.4 47.8 10.5 36.8 15.5 99.5 71.2 8.9 14.7 8.6 23.9 11.2 13.5 8.6 16.5 14.4 19.7 16.8 10.9 41.7 33.8 26.4 14.9 28.6 18.7 7.6 15.2 18.1 RFC2 "A1, RFC40" ENSG00000049541 "Replication factor C subunit 2" P35250 7 74231499-74254458 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029493 Approved Supported "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "HPA029493: AB_10603991" "unprognostic (1.25e-1)" "prognostic favorable (9.91e-4)" "unprognostic (1.44e-1)" "unprognostic (7.66e-3)" "unprognostic (1.17e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (2.08e-2)" "unprognostic (5.74e-2)" "unprognostic (2.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.09e-7)" "unprognostic (2.22e-1)" "unprognostic (6.65e-2)" "unprognostic (3.61e-2)" "unprognostic (2.59e-1)" 12.2 9.5 10.6 13.4 10.9 27.4 15.5 11.4 11.5 12.6 11.1 13.4 9.0 9.6 8.4 18.6 10.1 8.6 10.1 10.5 10.9 14.7 21.2 11.3 23.5 11.7 11.3 11.3 13.3 11.8 7.9 18.4 11.4 11.5 15.0 8.8 12.2 7.6 18.8 20.3 11.2 12.6 11.5 14.2 13.6 10.0 10.7 20.2 9.2 12.2 30.8 11.5 12.6 11.8 74.3 55.6 65.2 64.6 13.1 15.2 29.4 42.5 46.7 85.2 101.4 62.6 67.3 69.2 11.5 30.7 78.7 49.7 53.3 69.2 87.5 49.6 91.5 42.9 76.4 46.7 10.1 64.6 25.3 15.4 15.9 79.8 55.0 18.5 46.0 63.9 89.4 41.9 66.4 87.2 65.1 124.7 74.1 116.3 47.4 95.0 72.0 85.8 45.7 58.1 52.4 65.5 50.7 94.8 34.7 79.2 68.7 58.0 17.4 83.4 54.9 64.6 96.3 25.1 35.1 120.6 42.4 98.4 89.3 33.4 36.7 27.3 18.0 42.3 18.1 31.6 15.5 16.5 31.9 36.8 19.5 14.3 46.4 42.9 40.1 17.1 23.9 29.1 10.6 10.9 11.4 11.5 10.5 10.9 11.7 11.3 11.4 11.5 10.7 11.8 15.4 12.8 11.1 2.6 19.0 23.8 24.3 24.3 19.9 13.2 12.6 17.4 6.1 5.7 16.5 5.5 2.1 68.6 17.5 12.4 5.9 21.0 2.8 8.1 13.3 13.5 4.8 38.3 3.0 19.0 65.0 17.4 10.7 11.5 23.4 25.1 13.6 14.0 37.7 3.3 2.6 13.1 20.3 14.4 28.2 2.5 8.7 18.2 21.4 1.9 26.3 16.1 23.7 1.5 2.2 13.8 6.9 10.9 17.5 11.0 13.2 13.8 8.8 9.5 6.6 14.6 17.5 33.8 44.6 20.1 17.0 46.1 16.9 12.9 19.1 15.3 RFC4 "A1, RFC37" ENSG00000163918 "Replication factor C subunit 4" P35249 3 186789880-186807058 "Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 55.7;Spermatocytes: 86.7;Spermatogonia: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004557, HPA049123, HPA058507" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004557: AB_2178593, HPA049123: AB_2680642, HPA058507: AB_2683736" "unprognostic (2.45e-1)" "prognostic favorable (7.41e-5)" "unprognostic (2.84e-1)" "unprognostic (1.81e-3)" "unprognostic (1.03e-1)" "unprognostic (6.69e-3)" "prognostic unfavorable (6.75e-7)" "unprognostic (5.29e-3)" "unprognostic (1.15e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (7.38e-4)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (1.80e-2)" "unprognostic (4.98e-1)" "unprognostic (6.15e-2)" "unprognostic (2.16e-1)" 7.0 6.0 7.3 19.3 7.6 41.5 13.8 8.9 11.9 8.8 7.4 15.4 10.9 14.1 6.6 11.8 10.8 7.7 9.1 7.5 7.5 7.3 10.7 7.2 31.5 7.3 7.4 15.0 11.0 8.0 5.7 14.5 7.6 7.7 20.4 11.2 8.6 7.0 8.3 11.7 11.7 17.6 7.5 14.3 10.4 22.7 8.1 35.7 7.3 6.7 34.5 7.8 8.2 8.3 167.3 56.2 130.8 83.6 18.8 20.1 103.0 78.9 49.9 123.6 135.8 84.8 77.9 119.5 177.4 38.0 118.0 86.1 116.5 77.5 151.1 180.5 102.5 123.3 86.3 86.3 14.6 131.8 79.5 17.3 27.5 84.9 66.1 27.6 42.0 183.8 97.9 165.4 85.3 79.7 167.2 122.8 116.0 148.1 76.0 129.9 112.5 164.3 44.9 60.7 126.3 63.3 97.3 107.6 90.3 97.6 183.0 123.7 19.6 74.4 93.3 125.8 239.9 91.9 216.9 398.9 65.3 142.8 100.0 0.0 2.8 9.7 11.5 4.2 11.1 13.1 11.4 12.0 5.0 15.1 11.2 10.2 0.6 9.8 14.7 9.6 21.8 7.7 7.3 7.6 8.9 11.9 7.5 7.5 7.3 7.4 7.6 7.5 8.1 8.3 5.1 0.0 2.2 3.3 14.0 6.0 15.3 18.1 5.2 16.1 4.1 8.1 7.5 5.7 9.3 11.0 0.0 43.0 9.7 4.4 5.9 15.3 27.3 5.6 7.0 6.1 1.2 46.3 5.2 16.6 55.7 8.3 6.6 6.0 8.2 25.3 6.1 3.0 23.9 8.4 4.4 7.1 10.2 2.6 4.9 10.0 10.5 6.2 1.8 4.7 12.2 14.9 9.2 2.5 4.3 9.2 4.1 7.9 23.8 3.8 2.8 7.9 7.9 14.4 6.6 10.2 13.1 86.7 50.5 7.9 3.0 11.2 9.6 8.8 13.9 4.7 RFC5 RFC36 ENSG00000111445 "Replication factor C subunit 5" P40937 12 118013588-118033130 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041037 Supported Approved Nucleoplasm NA NA 6500 "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA041037: AB_10805834" "unprognostic (9.63e-2)" "prognostic favorable (8.05e-5)" "unprognostic (5.12e-3)" "unprognostic (2.25e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-2)" "unprognostic (1.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.35e-3)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.44e-1)" "unprognostic (2.15e-1)" "unprognostic (2.70e-1)" "unprognostic (5.06e-1)" 5.9 5.8 3.7 10.5 4.4 33.8 10.7 5.9 4.9 8.6 4.2 10.3 9.8 11.1 5.4 9.3 9.5 6.7 5.4 6.0 2.9 8.7 13.0 6.8 16.4 3.3 3.2 15.6 7.6 7.1 4.7 7.3 3.2 7.9 12.6 11.5 5.8 8.0 5.6 12.9 9.1 7.7 3.8 8.0 7.2 8.3 3.7 23.4 10.3 4.7 16.1 6.3 7.1 4.3 52.8 49.3 49.1 28.1 12.2 14.7 58.3 38.4 24.0 66.6 49.9 50.2 21.4 56.4 25.9 18.1 42.0 47.2 66.9 34.0 63.2 42.1 58.1 43.9 40.7 36.5 7.6 70.7 38.1 7.8 12.2 50.0 16.8 30.4 28.6 70.3 62.6 21.6 33.3 50.3 93.2 59.2 40.5 29.8 46.1 68.1 61.2 55.3 30.7 47.7 67.5 30.7 62.2 18.2 24.1 30.4 64.4 30.0 13.7 36.9 42.5 50.4 69.5 36.2 51.7 76.9 36.4 51.7 66.1 16.6 5.0 3.6 8.6 8.4 7.6 10.7 10.3 7.4 7.2 9.1 8.0 6.9 5.6 7.9 4.9 6.0 11.4 6.5 3.7 4.4 5.9 4.9 6.0 2.9 3.3 3.2 3.2 3.8 3.7 4.3 4.0 0.0 3.3 4.6 5.6 8.4 6.9 7.1 4.0 4.2 5.2 4.7 3.1 4.3 4.6 9.2 2.1 21.0 4.7 3.6 9.8 8.9 3.0 6.0 6.3 4.3 4.2 45.7 11.8 6.3 25.2 6.4 4.1 6.5 5.7 14.0 3.3 6.0 9.1 1.7 7.3 6.9 4.1 3.2 3.1 2.7 4.1 4.9 0.0 3.7 3.8 9.5 2.1 2.5 5.5 4.1 4.0 8.2 16.4 2.3 3.2 6.6 11.0 6.0 0.0 5.3 8.4 13.4 9.1 9.5 5.4 8.9 7.9 18.7 10.6 4.2 RFESD ENSG00000175449 "Rieske Fe-S domain containing" Q8TAC1 5 95646754-95684773 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.9" "Cell type enriched" "Detected in many" 7 "Erythroid cells: 278.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 41.3;K-562: 78.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016546 Uncertain Approved Nucleoplasm NA NA 48000 "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB016546: AB_630417" "unprognostic (1.15e-1)" "unprognostic (5.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.37e-2)" "unprognostic (6.07e-3)" "unprognostic (2.72e-1)" "unprognostic (1.33e-3)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (9.91e-2)" "unprognostic (8.24e-3)" "unprognostic (4.89e-2)" "unprognostic (5.83e-3)" "unprognostic (6.78e-2)" "unprognostic (9.03e-2)" "unprognostic (9.35e-2)" "unprognostic (1.09e-1)" 1.7 2.3 1.3 1.1 1.7 26.9 2.8 2.1 3.4 2.2 1.8 1.8 1.2 2.0 4.4 2.4 2.0 1.2 3.5 1.4 1.6 2.5 2.5 1.5 3.1 1.8 1.6 2.9 3.6 3.9 2.8 1.6 1.7 3.1 1.4 3.6 4.7 1.4 5.8 7.6 1.4 1.4 1.6 2.4 2.5 12.2 1.7 4.9 3.3 3.5 3.2 2.3 1.9 2.2 3.6 5.5 1.0 3.5 3.4 6.2 0.0 1.9 2.9 3.1 3.1 4.4 3.8 5.8 3.8 1.6 7.3 5.2 3.8 3.0 3.3 8.7 3.3 41.3 5.2 1.6 4.3 3.8 4.2 2.8 5.5 4.0 3.6 2.8 3.1 17.1 78.3 4.5 4.9 2.4 12.4 16.4 4.4 1.6 5.2 6.0 0.7 2.6 1.1 2.1 5.3 3.8 5.4 2.4 0.0 0.3 2.8 2.0 1.6 3.9 3.1 2.9 3.4 3.9 10.1 4.7 3.4 4.5 2.1 0.0 0.7 0.4 3.6 0.9 9.6 3.9 8.7 6.2 1.6 3.3 12.7 7.5 0.0 6.1 0.9 1.9 5.4 2.7 1.3 1.7 2.1 3.4 1.4 1.6 1.8 1.6 1.7 1.6 1.7 2.2 2.0 12.8 3.3 1.6 2.8 3.2 4.5 6.0 3.4 2.1 2.3 3.4 7.8 0.0 5.5 1.8 0.0 3.5 4.2 0.5 1.9 2.4 18.2 2.3 2.4 1.4 0.0 278.7 1.6 1.8 12.1 3.2 2.0 1.8 3.8 2.0 2.9 2.1 3.8 1.7 1.9 1.1 14.2 1.6 0.8 8.5 1.8 1.2 0.0 2.8 2.3 3.8 3.1 0.0 1.7 1.7 0.3 1.2 1.0 2.5 0.9 2.9 5.3 1.9 6.6 2.8 2.7 37.2 14.3 4.5 6.8 2.1 4.6 2.5 1.2 2.5 RGL3 FLJ32585 ENSG00000205517 "Ral guanine nucleotide dissociation stimulator like 3" Q3MIN7 19 11384341-11419328 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.1;parathyroid gland: 45.9;thyroid gland: 64.9" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Collecting duct cells: 51.5;Gastric mucus-secreting cells: 48.4;Sertoli cells: 39.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;CACO-2: 10.4;RT4: 22.0;SK-BR-3: 9.7;T-47d: 15.9" "Region enriched" "Detected in many" 6 "cerebellum: 9.0" "Low region specificity" "Detected in many" "HPA042763, HPA043615, HPA064578" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA042763: AB_10968569, HPA043615: AB_10959470, HPA064578: " "prognostic favorable (7.35e-4)" "unprognostic (3.12e-2)" "unprognostic (2.92e-1)" "unprognostic (5.69e-2)" "unprognostic (2.08e-1)" "unprognostic (6.60e-2)" "unprognostic (3.82e-2)" "unprognostic (5.31e-2)" "unprognostic (1.24e-2)" "unprognostic (1.48e-2)" "unprognostic (3.19e-3)" "unprognostic (5.99e-2)" "prognostic favorable (6.61e-4)" "unprognostic (4.17e-2)" "unprognostic (3.37e-1)" "unprognostic (3.21e-2)" "unprognostic (7.12e-3)" 7.3 11.5 1.8 0.7 1.6 0.0 7.4 1.9 2.5 13.3 6.9 2.9 1.4 4.8 9.5 1.1 9.5 2.1 9.2 2.2 2.2 41.1 10.6 8.9 0.6 2.7 2.4 2.5 21.0 45.9 15.4 5.6 2.8 6.5 1.3 0.8 5.9 9.4 2.0 1.3 1.8 0.8 1.7 8.2 13.8 0.6 2.9 0.2 64.9 0.6 0.3 5.3 5.7 2.3 0.0 0.6 0.0 0.1 1.1 0.2 17.7 1.1 1.4 0.6 2.0 10.4 7.4 0.0 6.5 1.3 2.6 4.6 0.0 0.0 0.1 0.0 0.0 0.1 4.2 3.3 2.7 0.0 0.0 0.0 0.1 0.1 0.0 4.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.9 1.4 0.0 0.7 2.2 6.3 22.0 1.0 5.2 0.2 9.7 3.3 3.7 15.9 0.0 0.0 3.3 0.0 2.5 0.9 0.0 0.6 1.0 0.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 1.6 1.9 2.5 2.2 2.2 2.7 2.4 2.8 1.7 2.9 2.3 3.1 19.2 21.0 32.3 1.1 0.1 2.1 0.4 1.8 0.3 3.3 4.6 4.6 12.8 12.4 51.5 0.0 12.9 0.0 2.2 11.7 8.6 0.0 14.8 9.6 5.8 10.3 0.0 0.5 4.2 11.9 4.1 48.4 18.4 1.3 3.1 26.0 5.8 3.0 0.0 0.6 7.7 2.0 7.4 0.3 0.2 3.7 1.5 5.4 4.7 0.0 16.9 0.0 1.5 0.5 5.7 5.3 0.4 0.6 1.4 0.0 4.6 1.7 0.6 39.5 9.9 18.7 0.6 1.7 0.0 0.0 12.0 0.2 0.8 2.4 2.0 RGMA RGM ENSG00000182175 "Repulsive guidance molecule BMP co-receptor a" Q96B86 15 93035273-93089204 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3;skeletal muscle: 199.1" "Cell type enhanced" "Detected in many" "Astrocytes: 143.3;Leydig cells: 119.0;Peritubular cells: 116.9;Prostatic glandular cells: 61.3;Skeletal myocytes: 69.3;Squamous epithelial cells: 58.3" "Cancer enriched" "Detected in many" 6 "glioma: 26.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 50.0;BEWO: 14.6;MOLT-4: 15.5;NTERA-2: 22.2;REH: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012343, HPA039880, HPA044222" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 2000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB012343: AB_777667, HPA039880: AB_2676723, HPA044222: AB_2678861" "unprognostic (3.21e-2)" "unprognostic (1.59e-1)" "unprognostic (8.85e-2)" "unprognostic (3.96e-3)" "unprognostic (5.73e-2)" "unprognostic (4.72e-3)" "unprognostic (2.53e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (6.25e-2)" "unprognostic (3.59e-4)" "unprognostic (8.11e-2)" "unprognostic (2.92e-2)" "unprognostic (1.73e-1)" "unprognostic (7.98e-5)" 30.2 3.2 62.1 22.5 73.8 0.4 30.3 72.5 59.1 55.9 7.7 79.4 9.9 50.9 2.9 57.4 39.9 7.7 29.4 60.4 68.0 3.6 0.6 4.6 2.4 126.3 113.9 38.5 11.4 0.8 6.9 1.3 70.4 12.8 6.2 1.0 24.2 6.4 199.1 17.1 42.9 60.6 91.5 1.3 73.6 33.5 120.6 2.6 10.0 45.0 3.4 10.0 29.2 62.8 2.1 0.3 50.0 0.8 10.3 5.7 14.6 0.3 0.0 0.0 0.0 0.6 0.6 0.1 0.2 0.4 0.0 3.4 8.4 0.2 0.0 0.0 9.2 0.1 0.3 0.0 0.0 0.1 0.2 6.1 0.2 0.0 0.0 0.3 0.0 0.9 0.0 0.1 0.0 1.0 15.5 0.2 22.2 0.1 0.0 13.1 11.4 0.1 0.0 0.5 5.1 3.0 0.5 0.2 0.0 2.6 4.0 2.7 0.0 0.1 10.4 0.3 0.1 0.1 0.0 0.2 0.2 0.2 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 62.1 73.8 72.5 59.1 60.4 68.0 126.3 113.9 70.4 91.5 120.6 62.8 4.2 0.0 1.5 143.3 0.5 5.5 20.4 10.2 40.5 1.9 7.5 4.4 4.4 0.0 3.9 0.0 2.1 4.4 0.5 0.3 0.0 6.5 1.2 0.6 10.9 2.7 0.0 0.4 16.8 0.7 1.2 40.5 1.5 2.3 0.0 0.6 1.8 0.3 2.1 0.0 2.8 0.0 12.2 2.5 2.3 6.4 119.0 1.6 3.6 9.4 0.6 4.5 0.0 11.1 1.6 0.4 0.0 116.9 0.1 61.3 0.0 0.1 1.3 1.2 13.1 69.3 20.3 0.9 43.8 58.3 2.8 2.5 1.4 0.1 0.1 29.2 RGS14 ENSG00000169220 "Regulator of G protein signaling 14" O43566 5 177357924-177372596 "Predicted intracellular proteins" "Cell cycle, Cell division" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 110.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 72.8;Proximal tubular cells: 113.7;Squamous epithelial cells: 95.8;Suprabasal keratinocytes: 115.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 110.4;cerebral cortex: 67.9;hippocampal formation: 56.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 112.5;HMC-1: 95.4;NB-4: 44.8;RPMI-8226: 57.9" "Group enriched" "Detected in many" 10 "amygdala: 66.0;basal ganglia: 57.9;cerebral cortex: 46.8;hippocampal formation: 93.6;white matter: 23.8" "Region enhanced" "Detected in many" "basal ganglia: 102.1" "HPA046847, HPA061819" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Intermediate filaments" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Vesicles, Plasma membrane, Intermediate filaments" "HPA046847: AB_2679836, HPA061819: " "unprognostic (6.05e-3)" "unprognostic (1.65e-2)" "unprognostic (8.57e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.97e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.95e-2)" "unprognostic (4.34e-2)" "unprognostic (2.04e-3)" "unprognostic (2.71e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.17e-2)" "unprognostic (2.78e-2)" 3.5 2.8 16.0 13.9 110.4 22.4 2.9 0.0 67.9 3.1 1.8 3.7 6.3 2.3 0.4 10.0 7.7 4.3 1.3 56.4 4.5 8.5 28.7 5.5 18.1 0.0 0.4 1.1 3.7 1.5 2.4 1.4 0.1 3.5 0.9 0.0 6.2 2.1 2.6 6.1 11.0 1.8 0.1 27.7 4.9 1.9 15.2 16.3 6.1 0.9 6.6 4.1 5.0 3.2 5.4 1.1 2.3 1.4 0.1 0.0 3.7 0.2 0.0 0.5 0.6 3.7 10.4 13.3 7.3 0.4 1.3 10.6 0.2 3.8 0.0 112.5 0.5 20.7 1.0 4.7 0.9 16.3 95.4 1.8 1.1 0.6 0.7 1.4 0.6 14.9 3.5 26.5 0.2 0.4 21.7 44.8 1.7 5.4 2.8 10.2 0.3 57.9 1.5 1.6 0.4 1.9 0.4 0.4 8.8 0.0 3.5 25.2 1.1 0.2 1.9 0.0 9.7 13.9 7.1 5.8 1.6 30.3 2.4 70.6 39.9 148.8 62.4 37.9 63.0 27.7 57.9 57.8 39.8 26.6 47.4 43.1 140.0 23.6 41.2 17.6 60.9 43.9 16.0 110.4 0.0 67.9 56.4 4.5 0.0 0.4 0.1 0.1 15.2 3.2 5.3 6.4 4.4 2.6 27.3 68.8 23.9 15.4 72.8 0.7 8.9 11.8 2.3 37.1 5.6 11.0 2.1 3.9 41.4 4.2 31.3 11.4 0.6 19.5 2.0 6.5 4.8 7.4 4.6 16.7 10.4 5.4 12.2 8.1 24.7 2.8 8.2 64.0 26.1 0.0 1.5 10.0 10.2 17.0 23.3 1.5 2.8 18.2 21.4 6.5 18.1 9.9 48.4 0.5 0.3 12.8 17.2 2.2 18.0 14.1 16.8 113.7 11.7 2.0 0.0 1.6 4.6 0.1 20.3 95.8 115.1 3.3 51.2 1.1 4.4 20.0 RHBDL3 "RHBDL4, VRHO" ENSG00000141314 "Rhomboid like 3" P58872 17 32265832-32324659 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 23.0;heart muscle: 13.8;retina: 26.1" "Cell type enhanced" "Detected in some" "Astrocytes: 41.8;Excitatory neurons: 46.8;Horizontal cells: 102.6;Oligodendrocyte precursor cells: 75.9;Rod photoreceptor cells: 34.2" "Cancer enriched" "Detected in some" 4 "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;AF22: 4.7;AN3-CA: 3.8;GAMG: 5.5;HDLM-2: 6.0;NTERA-2: 6.5;U-2 OS: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059607 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA059607: AB_2684081" "unprognostic (7.70e-2)" "unprognostic (3.71e-2)" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.91e-1)" "unprognostic (2.83e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "unprognostic (2.18e-3)" "unprognostic (2.11e-1)" "unprognostic (1.23e-1)" "unprognostic (8.87e-2)" 0.4 5.1 9.4 0.4 10.6 0.1 0.4 14.1 23.0 2.2 3.4 0.8 0.2 1.6 0.7 0.5 2.3 0.2 13.8 13.6 9.6 0.6 0.0 0.3 0.1 14.2 19.0 2.2 0.5 0.8 2.9 0.2 15.9 1.6 0.5 26.1 0.3 3.0 0.1 0.3 0.4 0.7 12.1 0.1 0.7 2.0 11.6 0.2 0.3 0.1 0.2 2.3 1.8 14.8 0.0 4.6 4.7 3.8 0.7 0.0 0.1 0.2 0.5 1.4 1.7 0.0 0.0 0.0 0.2 0.5 5.5 0.0 1.2 0.0 0.3 6.0 1.5 0.8 3.1 0.2 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.2 0.0 0.3 0.5 0.0 0.3 0.1 0.1 0.0 6.5 0.0 0.0 0.8 0.0 0.0 0.0 2.6 0.1 1.3 0.6 0.1 0.1 1.5 0.3 0.0 0.0 0.0 4.4 0.2 2.2 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 10.6 14.1 23.0 13.6 9.6 14.2 19.0 15.9 12.1 11.6 14.8 0.6 0.0 0.0 41.8 0.0 0.4 0.5 0.0 0.0 12.1 0.8 0.6 7.4 0.0 0.0 0.0 6.2 1.5 0.1 0.0 0.0 0.1 3.2 0.3 0.2 0.7 0.0 0.0 46.8 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.4 0.0 0.4 102.6 15.2 0.4 0.0 0.3 0.3 2.4 0.9 0.1 0.0 4.7 0.0 7.4 0.0 75.9 4.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 34.2 0.0 0.1 0.5 0.1 1.2 0.0 0.1 0.5 0.1 0.0 0.0 0.6 RHBG SLC42A2 ENSG00000132677 "Rh family B glycoprotein" Q9H310 1 156369211-156385219 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 9.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 89.9;Theca cells: 91.3" "Group enriched" "Detected in some" 5 "liver cancer: 14.2;renal cancer: 5.1;urothelial cancer: 4.1" "Region enriched" "Detected in single" 17 "cerebellum: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 2.9;Hep G2: 3.0;RT4: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042726, HPA048489" Enhanced Approved Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA042726: AB_2678131, HPA048489: AB_2680417" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" "unprognostic (4.55e-3)" "unprognostic (5.04e-2)" "unprognostic (2.95e-2)" "unprognostic (3.76e-3)" "unprognostic (2.00e-1)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.45e-1)" "unprognostic (3.72e-1)" "unprognostic (3.63e-2)" "unprognostic (4.91e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-3)" "prognostic favorable (8.06e-4)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.8 1.9 0.0 0.0 0.1 0.0 2.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 22.0 0.0 0.0 0.0 0.0 19.6 0.3 10.3 0.3 0.0 0.1 0.0 0.0 0.2 0.6 0.1 1.3 0.0 0.1 0.0 89.9 0.0 10.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.1 1.3 0.2 0.0 0.0 0.0 0.8 2.3 0.4 0.0 0.4 0.0 0.0 91.3 0.0 0.1 RHEBL1 "FLJ25797, MGC34869, RHEB2" ENSG00000167550 "RHEB like 1" Q8TAI7 12 49064676-49070025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Cell type enhanced" "Detected in many" "dendritic cells: 10.6;Granulosa cells: 12.2;NK-cells: 14.4;Plasma cells: 8.2;Respiratory ciliated cells: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 16.1" "Group enriched" "Detected in all" 5 "granulocytes: 16.1;T-cells: 10.4" "Cell line enhanced" "Detected in many" "HDLM-2: 30.8;U-266/84: 61.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA053111, HPA061001" Uncertain Uncertain Nucleoplasm,Centrosome NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Centrosome" "HPA053111: AB_2682047, HPA061001: AB_2684409" "unprognostic (2.94e-1)" "unprognostic (1.11e-3)" "unprognostic (2.36e-2)" "unprognostic (9.81e-3)" "unprognostic (8.76e-2)" "unprognostic (2.03e-2)" "unprognostic (3.03e-5)" "unprognostic (9.13e-2)" "unprognostic (9.02e-3)" "unprognostic (2.13e-1)" "unprognostic (3.98e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-10)" "unprognostic (4.67e-2)" "unprognostic (1.11e-1)" "unprognostic (7.66e-2)" "unprognostic (2.07e-1)" 0.8 0.2 2.2 1.5 2.3 2.1 0.8 2.1 4.1 0.3 1.7 0.5 0.5 1.4 1.0 0.4 2.6 0.5 0.5 2.2 2.2 0.3 0.3 1.2 3.6 2.3 2.1 0.3 0.2 0.2 0.3 0.6 2.1 0.2 0.8 0.8 0.4 0.2 0.2 2.6 0.9 0.5 1.9 2.5 0.6 1.5 2.1 1.6 0.3 1.1 1.9 0.4 0.4 2.4 1.7 3.4 2.2 4.8 1.2 0.2 2.1 1.4 4.8 9.1 9.9 3.2 2.9 4.7 1.5 0.4 4.7 1.8 1.5 1.8 3.9 30.8 0.4 4.9 2.9 1.9 1.0 2.4 10.1 0.5 0.8 4.5 1.4 0.6 3.5 8.3 6.1 14.8 3.3 1.7 2.3 13.3 3.0 6.0 3.9 4.7 3.2 7.9 0.7 0.2 1.0 2.9 1.4 1.3 8.4 2.6 0.5 3.5 1.3 2.7 4.4 5.3 1.7 17.8 61.0 3.0 2.3 7.2 1.2 16.1 0.3 0.7 7.6 1.8 10.4 2.0 3.2 4.1 0.8 2.9 1.0 3.8 0.7 1.4 1.7 1.0 6.7 1.4 2.2 2.3 2.1 4.1 2.2 2.2 2.3 2.1 2.1 1.9 2.1 2.4 2.8 0.0 0.0 0.3 6.8 1.3 0.5 1.9 4.0 1.8 1.2 1.7 1.5 1.5 1.8 0.0 0.0 0.1 10.6 0.1 0.0 0.5 0.5 2.8 0.3 2.6 0.0 8.0 6.9 0.2 0.5 1.4 0.5 0.4 0.0 12.2 1.8 0.1 1.8 3.3 2.3 0.2 0.0 0.3 2.0 0.6 0.0 3.7 0.0 0.0 4.5 0.6 14.4 0.5 0.3 0.2 0.0 0.0 8.2 0.4 0.1 0.1 12.0 0.4 0.0 1.3 1.8 0.9 5.4 4.8 2.0 0.1 5.7 0.2 0.4 0.2 RHNO1 "C12orf32, HKMT1188, MGC13204, RHINO" ENSG00000171792 "RAD9-HUS1-RAD1 interacting nuclear orphan 1" Q9BSD3 12 2876258-2889524 "Predicted intracellular proteins" "Cell cycle, DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (3.90e-2)" "unprognostic (4.86e-2)" "unprognostic (6.48e-3)" "unprognostic (1.86e-1)" "unprognostic (5.15e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (7.15e-2)" "unprognostic (1.19e-2)" "unprognostic (1.12e-3)" "unprognostic (4.83e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (5.74e-13)" "unprognostic (1.97e-1)" "unprognostic (1.64e-1)" "unprognostic (2.54e-2)" "unprognostic (4.53e-2)" 5.5 8.8 12.5 13.1 10.9 17.1 12.1 11.3 13.5 13.1 12.2 14.1 11.0 11.5 22.7 17.5 12.2 10.7 7.2 12.5 13.5 9.1 5.2 9.2 19.6 9.7 10.0 15.6 8.7 13.6 12.0 11.6 12.4 13.4 14.5 13.0 12.1 12.7 6.5 14.1 10.1 11.5 8.3 12.8 10.6 11.3 12.2 25.7 16.6 3.9 20.9 12.4 10.6 16.7 42.3 54.2 64.5 32.9 14.8 18.6 67.7 40.7 43.3 51.0 50.1 66.3 91.4 34.5 22.8 42.4 64.2 32.4 43.0 50.9 62.4 138.6 28.2 45.0 25.3 39.6 20.0 50.8 33.4 18.4 32.4 50.3 104.8 36.7 52.5 71.8 41.1 81.2 61.3 60.9 92.8 28.5 149.7 52.8 32.4 61.6 77.7 26.8 41.2 52.3 21.6 32.0 56.1 35.6 30.0 117.7 69.3 47.2 37.1 55.1 83.6 62.6 85.3 18.5 37.9 90.6 25.3 41.8 51.7 23.7 23.3 34.9 23.8 22.0 31.2 27.7 36.4 31.9 26.5 41.9 36.8 24.7 4.8 26.5 23.9 15.8 54.7 25.9 12.5 10.9 11.3 13.5 12.5 13.5 9.7 10.0 12.4 8.3 12.2 16.7 3.8 0.0 5.9 3.3 14.0 7.8 10.0 27.7 6.2 6.8 11.9 13.3 7.6 7.2 10.4 11.0 8.4 40.1 6.5 7.2 23.5 13.9 6.5 8.1 7.0 8.7 10.3 33.2 6.6 8.4 34.0 8.2 7.1 9.0 14.0 17.4 12.5 3.9 31.7 10.1 6.4 16.3 14.2 15.5 8.0 14.6 12.2 10.2 3.6 2.8 32.3 20.4 10.3 3.0 6.5 6.9 9.6 8.6 11.4 18.1 13.2 15.4 6.4 9.8 0.0 3.1 7.5 67.1 46.0 18.8 7.1 21.8 17.3 8.4 17.3 12.5 RHOD "ARHD, Rho, RhoHP1" ENSG00000173156 "Ras homolog family member D" O00212 11 67056847-67072017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 182.2;liver: 122.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 124.7;Ductal cells: 102.8;Exocrine glandular cells: 141.6;Pancreatic endocrine cells: 271.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 156.0;CAPAN-2: 109.2;HaCaT: 135.9;HBEC3-KT: 179.8;hTCEpi: 208.6;MCF7: 101.0;T-47d: 148.7" "Group enriched" "Detected in many" 4 "cerebellum: 14.9;pons and medulla: 5.1" "Low region specificity" "Detected in some" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (2.12e-2)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.89e-3)" "unprognostic (1.65e-1)" "unprognostic (3.61e-3)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (3.10e-4)" "unprognostic (5.85e-2)" "unprognostic (4.39e-2)" "unprognostic (1.38e-3)" "unprognostic (8.89e-2)" "unprognostic (2.56e-2)" "unprognostic (2.24e-1)" "unprognostic (5.89e-2)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" 13.0 2.5 3.3 2.5 3.0 0.0 13.9 4.0 4.7 36.7 18.1 9.1 9.1 12.5 1.1 182.2 11.4 6.6 53.4 3.5 2.7 24.0 122.9 8.9 1.1 3.5 2.9 11.8 36.2 24.8 15.6 7.3 3.1 18.0 1.2 0.8 34.9 7.1 28.2 58.6 7.3 3.3 2.8 2.6 15.6 4.9 2.7 1.4 23.0 5.0 6.0 7.8 60.1 2.5 156.0 12.2 0.8 15.8 2.3 1.7 23.1 13.7 22.5 8.2 8.1 11.4 109.2 0.0 24.6 16.1 0.0 135.9 1.6 179.8 1.5 0.0 0.5 0.0 62.6 1.3 21.7 0.1 0.2 21.4 208.6 2.5 54.2 10.1 8.3 0.0 0.0 10.6 2.5 101.0 0.2 0.1 17.8 16.6 62.6 0.0 0.0 0.3 76.3 11.2 1.0 0.0 70.9 4.0 6.1 2.9 148.7 0.5 5.1 0.1 0.4 2.2 0.8 0.0 3.5 0.2 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.0 4.0 4.7 3.5 2.7 3.5 2.9 3.1 2.8 2.7 2.5 6.6 16.0 4.4 0.7 1.3 32.9 34.6 124.7 56.9 0.2 38.8 57.7 28.2 28.6 29.0 16.5 0.0 29.9 0.6 67.7 45.0 102.8 16.7 6.5 8.1 7.2 4.2 3.6 0.4 141.6 34.1 14.8 24.5 9.7 0.0 8.0 5.7 46.3 3.6 0.0 0.3 4.5 10.2 1.0 4.0 9.4 11.8 1.0 8.8 1.0 0.6 13.6 0.0 0.5 0.2 271.3 66.1 22.2 1.7 61.0 90.8 24.7 19.3 0.6 0.0 2.1 9.1 0.9 4.7 55.4 57.7 36.0 2.8 1.5 6.6 71.8 RHOQ "ARHQ, RASL7A, TC10" ENSG00000119729 "Ras homolog family member Q" P17081 2 46541806-46584688 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 189.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.5;classical monocyte: 2.5;eosinophil: 4.2;intermediate monocyte: 2.7;memory B-cell: 1.7;myeloid DC: 1.6;naive B-cell: 2.4;neutrophil: 4.8;non-classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 164.0;ASC TERT1: 132.0;SK-MEL-30: 150.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044938 Approved Vesicles,Cytosol No No "Cluster 24: B-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "HPA044938: AB_2679149" "unprognostic (1.24e-1)" "unprognostic (1.30e-2)" "unprognostic (5.82e-2)" "unprognostic (2.07e-2)" "unprognostic (3.61e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.60e-5)" "unprognostic (2.01e-2)" "unprognostic (9.24e-2)" "unprognostic (2.11e-2)" "unprognostic (1.97e-1)" "unprognostic (5.43e-2)" "unprognostic (3.88e-3)" "unprognostic (1.39e-2)" "unprognostic (1.87e-1)" "unprognostic (7.68e-2)" "unprognostic (3.52e-2)" 96.9 35.7 34.8 30.1 40.1 12.4 64.8 38.9 41.4 59.6 43.9 67.0 11.0 53.2 67.7 18.9 59.3 26.7 196.8 34.3 44.7 44.3 22.6 56.0 23.8 40.9 44.2 40.8 28.6 50.4 29.5 28.6 38.9 50.6 13.5 27.7 32.7 36.5 162.4 28.1 35.3 38.4 39.2 42.7 32.8 10.1 36.8 9.9 39.1 181.3 19.1 62.8 44.7 43.5 12.3 12.4 21.0 28.6 164.0 132.0 3.7 32.8 84.1 16.2 24.4 6.2 4.1 28.7 34.0 58.5 52.4 5.8 20.6 9.8 29.3 10.2 15.3 8.2 9.8 20.9 81.8 8.8 10.7 118.1 17.3 20.1 22.5 39.0 19.3 3.1 12.1 44.0 35.2 8.1 6.9 17.9 20.8 8.9 14.4 5.3 34.5 10.1 23.1 22.4 15.3 50.3 11.6 16.4 150.8 32.9 9.0 20.7 13.2 50.1 44.8 49.3 14.1 48.5 17.7 28.4 73.6 22.1 18.4 1.5 2.5 4.2 0.4 2.7 0.3 1.7 0.2 0.4 1.6 2.4 0.0 0.3 4.8 0.3 1.9 0.6 0.3 0.7 34.8 40.1 38.9 41.4 34.3 44.7 40.9 44.2 38.9 39.2 36.8 43.5 27.9 57.7 22.4 65.3 38.1 22.4 31.0 18.1 11.4 21.1 30.4 22.4 189.2 14.3 22.1 20.2 10.4 14.6 32.2 1.0 17.6 21.4 30.8 22.1 90.2 23.4 6.0 2.1 12.8 32.0 3.6 82.8 4.1 24.6 12.0 12.1 17.5 12.2 44.5 121.1 27.7 5.5 8.2 90.9 77.8 11.4 35.4 90.7 42.7 68.4 55.1 52.9 15.5 52.3 41.5 22.4 0.3 42.5 42.0 41.2 0.2 30.1 18.8 24.2 46.0 54.2 82.3 2.3 4.5 6.8 19.7 25.9 17.0 10.9 1.9 31.9 RHOT1 "ARHT1, FLJ11040, MIRO-1, MIRO1" ENSG00000126858 "Ras homolog family member T1" Q8IXI2 17 32142454-32253374 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010687, CAB068223, CAB068224" Supported NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" "CAB068223: AB_2665691, CAB068224: AB_2665692, HPA010687: AB_1079813" "unprognostic (3.28e-2)" "unprognostic (4.02e-3)" "unprognostic (6.85e-2)" "unprognostic (3.53e-1)" "unprognostic (1.57e-2)" "unprognostic (5.49e-2)" "unprognostic (1.59e-3)" "unprognostic (1.59e-2)" "unprognostic (7.02e-3)" "unprognostic (1.29e-1)" "unprognostic (1.38e-1)" "unprognostic (5.05e-1)" "unprognostic (1.01e-2)" "unprognostic (2.97e-2)" "unprognostic (2.58e-1)" "unprognostic (3.90e-1)" "unprognostic (4.08e-2)" 19.1 26.9 19.9 9.6 20.8 19.7 19.5 20.5 29.4 16.6 12.5 19.8 11.4 16.3 15.0 14.9 14.4 11.4 24.8 22.0 18.5 17.6 16.8 17.3 10.9 18.1 17.5 17.7 15.5 38.1 14.2 18.6 19.8 17.1 11.3 50.9 17.3 19.1 28.4 28.5 12.2 16.0 18.7 12.2 17.3 12.3 19.9 19.4 25.0 34.5 11.2 16.6 15.5 24.8 14.1 26.2 21.9 22.8 25.8 28.9 13.2 22.7 18.2 24.2 26.0 13.8 9.0 18.2 22.3 18.7 26.5 24.9 34.3 13.8 29.1 14.4 25.9 21.4 15.8 21.0 35.4 28.1 15.3 15.3 40.7 20.7 23.8 40.5 21.1 36.7 48.1 14.9 21.5 10.6 52.1 23.0 18.0 16.7 12.6 28.6 32.4 32.2 17.5 8.4 20.0 18.1 22.8 14.1 38.4 26.1 31.9 38.1 16.3 17.0 17.5 19.6 16.2 22.0 22.9 19.9 20.5 26.7 28.9 3.0 5.8 5.4 2.1 4.9 2.3 2.1 2.3 2.1 5.3 4.0 1.8 2.3 3.6 3.4 5.2 1.8 1.3 2.8 19.9 20.8 20.5 29.4 22.0 18.5 18.1 17.5 19.8 18.7 19.9 24.8 16.5 28.9 38.8 88.8 17.8 25.9 13.5 14.4 27.9 61.5 21.4 18.0 38.1 14.3 18.7 16.5 70.9 28.4 14.1 12.3 33.2 17.0 19.6 14.5 15.5 17.9 16.9 31.5 97.3 13.1 20.3 19.3 15.3 13.9 27.3 24.8 18.9 18.3 33.7 57.2 89.9 9.3 22.4 46.4 29.1 20.6 30.1 33.2 16.0 76.8 45.1 128.9 29.9 68.3 65.9 13.5 14.4 24.0 11.6 13.7 22.8 21.3 15.1 58.7 26.3 24.8 21.9 63.0 40.3 24.3 53.0 22.7 18.9 24.5 13.9 11.4 RIMKLB "FAM80B, KIAA1238, NAAGS, NAAGS-I" ENSG00000166532 "Ribosomal modification protein rimK like family member B" Q9ULI2 12 8681600-8783095 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 184.2;Endometrial ciliated cells: 191.3;Glandular and luminal cells: 1012.9;Late spermatids: 300.3" "Cancer enhanced" "Detected in many" "testis cancer: 17.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 145.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059552 Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Centriolar satellite" "HPA059552: " "unprognostic (5.29e-3)" "unprognostic (2.26e-2)" "unprognostic (1.89e-5)" "unprognostic (2.40e-2)" "unprognostic (2.30e-1)" "unprognostic (3.35e-2)" "unprognostic (6.56e-2)" "unprognostic (8.52e-2)" "unprognostic (8.67e-3)" "unprognostic (1.76e-1)" "unprognostic (3.25e-1)" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (2.16e-2)" "unprognostic (3.02e-1)" "unprognostic (3.74e-1)" "unprognostic (3.99e-1)" 27.6 10.9 20.1 8.0 23.0 21.0 24.1 23.9 18.6 29.5 19.9 30.5 5.4 40.1 15.9 11.1 29.4 14.9 14.4 20.9 23.7 11.8 3.1 19.4 9.1 27.5 24.8 30.1 8.1 22.2 12.8 24.5 22.3 14.1 7.0 19.1 11.8 14.1 13.7 13.0 12.8 27.6 26.7 13.5 11.0 32.4 24.9 13.7 20.0 9.4 7.0 15.4 21.7 21.0 3.7 18.1 43.5 44.9 5.7 5.4 63.0 19.6 8.8 16.1 10.5 1.5 20.6 27.9 16.2 11.7 17.9 6.3 21.5 23.9 17.1 0.5 13.9 13.3 52.4 0.2 6.6 4.1 13.3 11.7 10.4 14.4 24.2 10.1 21.0 22.9 18.0 0.0 9.4 11.8 27.0 2.0 53.2 0.0 1.0 42.0 60.5 0.1 22.8 10.2 1.4 28.2 17.5 24.9 19.4 70.9 6.0 13.4 41.2 15.7 51.0 8.6 6.4 0.2 0.0 145.9 13.3 2.9 10.9 2.1 1.2 0.3 0.8 0.3 1.0 0.7 0.8 1.3 0.5 1.3 1.4 0.5 0.1 1.2 0.5 0.4 0.0 1.0 20.1 23.0 23.9 18.6 20.9 23.7 27.5 24.8 22.3 26.7 24.9 21.0 69.8 28.9 42.9 99.6 13.3 15.2 23.3 16.6 27.9 25.5 10.9 11.4 15.6 7.2 25.7 12.9 0.0 61.0 4.2 1.0 15.6 12.8 184.2 191.3 99.5 38.5 9.0 30.9 33.0 3.0 18.6 27.3 4.1 1012.9 12.0 72.3 22.9 0.0 19.9 13.5 52.7 2.1 16.2 8.8 8.0 300.3 23.3 12.4 33.8 41.2 2.0 34.2 5.2 78.9 9.5 5.8 3.7 30.9 3.8 23.4 6.7 9.1 33.9 3.6 13.1 15.6 29.6 77.1 38.3 17.8 13.4 136.5 11.0 27.7 1.5 21.5 RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500696-104256094 "Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 50.6;brain: 48.2;retina: 102.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 383.6;Cone photoreceptor cells: 706.8;Excitatory neurons: 1589.3;Inhibitory neurons: 1234.9;Oligodendrocyte precursor cells: 577.0;Rod photoreceptor cells: 1088.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 9.2;RT4: 7.3;SCLC-21H: 16.5;SuSa: 8.8;U-2 OS: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: AB_2685678" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (4.47e-2)" "unprognostic (5.51e-2)" "unprognostic (2.82e-1)" "unprognostic (7.09e-3)" "unprognostic (2.02e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (8.01e-3)" "unprognostic (1.40e-2)" "unprognostic (6.34e-2)" "unprognostic (1.67e-5)" "unprognostic (8.12e-4)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" 0.2 50.6 22.4 0.2 27.1 0.4 0.7 35.5 48.2 7.5 0.0 0.1 0.4 0.6 0.9 0.3 5.9 0.9 0.1 18.4 16.4 0.3 0.1 0.1 0.3 5.5 9.7 2.0 0.7 0.0 15.0 0.4 6.4 1.7 0.1 102.3 0.8 1.0 0.2 0.3 0.5 1.3 3.5 0.1 0.6 2.8 16.7 0.8 1.3 0.1 0.2 1.7 2.4 29.4 4.6 0.0 4.8 0.0 0.0 0.1 0.0 0.4 0.3 1.0 1.3 0.1 0.3 9.2 0.1 0.1 1.4 0.3 1.9 0.8 2.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 1.0 1.5 0.0 1.2 0.0 0.5 0.0 0.4 0.9 0.0 4.0 0.0 0.5 0.0 0.0 0.0 0.0 7.3 16.5 3.3 0.0 0.1 0.7 8.8 0.4 0.2 0.0 0.0 6.5 0.1 0.1 1.2 0.0 0.1 0.4 0.3 0.3 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 22.4 27.1 35.5 48.2 18.4 16.4 5.5 9.7 6.4 3.5 16.7 29.4 0.4 28.9 22.5 38.5 0.2 0.3 1.8 2.8 1.8 383.6 0.7 0.6 0.9 1.5 16.9 0.0 706.8 0.5 0.1 0.2 1.9 0.1 34.2 2.1 0.4 4.9 8.4 0.0 1589.3 0.0 0.3 3.7 0.0 3.7 16.4 18.0 0.7 0.3 0.3 67.3 1234.9 0.9 0.0 0.6 0.8 20.1 72.1 2.5 1.8 63.7 0.6 86.6 1.0 577.0 27.0 0.3 1.2 29.3 0.3 4.1 2.0 0.2 10.6 1088.7 0.0 0.8 1.0 34.8 15.7 0.8 0.4 0.1 2.1 0.1 1.5 1.1 RIN3 FLJ22439 ENSG00000100599 "Ras and Rab interactor 3" Q8TB24 14 92513781-92688994 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 46.3" "Cell type enhanced" "Detected in many" "Kupffer cells: 125.1;Macrophages: 78.7;Microglial cells: 100.2;monocytes: 109.8;NK-cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 35.7;classical monocyte: 43.4;eosinophil: 54.1;intermediate monocyte: 40.4;myeloid DC: 41.6;neutrophil: 40.2;NK-cell: 21.5;non-classical monocyte: 50.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "HMC-1: 108.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA079218 Approved NA NA 7400 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA079218: " "unprognostic (1.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.93e-1)" "unprognostic (1.87e-1)" "unprognostic (7.18e-2)" "unprognostic (6.40e-2)" "unprognostic (2.44e-1)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (3.07e-3)" "unprognostic (5.69e-3)" "unprognostic (5.13e-2)" "unprognostic (5.90e-3)" "unprognostic (2.88e-2)" "unprognostic (6.95e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" 10.5 13.6 4.3 9.6 3.6 46.3 8.1 4.1 5.3 7.3 2.8 19.1 6.6 15.4 1.6 6.7 8.7 8.1 8.6 4.4 6.6 4.5 12.4 16.3 6.1 9.6 5.9 6.7 2.2 5.4 2.7 6.4 7.0 7.0 4.8 0.2 5.1 5.1 3.2 5.3 9.7 10.2 7.5 22.8 6.4 5.2 9.1 10.9 5.0 2.9 5.3 10.6 8.6 8.6 10.3 19.8 4.4 1.7 1.7 14.3 15.0 12.9 14.0 12.0 8.0 7.5 17.5 0.0 12.1 19.1 8.2 22.0 3.1 0.1 5.5 10.6 3.9 21.4 1.5 8.1 8.7 6.9 108.1 8.1 7.7 11.5 4.8 4.7 7.1 2.6 3.1 0.5 5.0 6.5 3.3 16.3 2.7 1.1 6.0 2.7 2.1 0.2 4.9 6.9 1.0 0.0 6.2 2.1 9.5 4.3 0.1 2.5 12.5 13.8 10.8 20.1 10.9 3.1 0.0 0.2 13.5 0.3 18.1 35.7 43.4 54.1 10.1 40.4 3.4 7.8 4.7 4.9 41.6 8.5 6.8 7.7 40.2 21.5 50.8 1.8 3.0 24.5 4.3 3.6 4.1 5.3 4.4 6.6 9.6 5.9 7.0 7.5 9.1 8.6 19.2 0.0 8.9 18.3 28.2 3.8 2.0 3.4 0.6 2.2 3.7 5.5 4.7 1.5 2.2 0.0 0.0 5.1 44.0 9.2 0.0 1.6 10.2 2.2 3.5 15.4 0.0 12.6 6.9 1.4 3.1 4.2 1.1 2.6 51.4 5.4 8.2 14.9 49.3 0.0 5.2 7.3 4.1 125.1 50.8 6.6 5.3 78.7 12.4 100.2 109.8 0.0 114.4 20.6 0.9 10.1 3.8 18.8 9.7 3.8 9.5 6.2 2.5 0.3 13.1 10.1 4.6 19.1 4.0 1.1 2.7 12.7 32.5 1.9 8.9 3.6 RMI1 "BLAP75, C9orf76, FLJ12888" ENSG00000178966 "RecQ mediated genome instability 1" Q9H9A7 9 83980798-84004074 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 70.0;Late spermatids: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021661 Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" "HPA021661: " "unprognostic (9.59e-2)" "unprognostic (7.96e-2)" "unprognostic (6.72e-3)" "unprognostic (3.03e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.65e-1)" "unprognostic (3.39e-3)" "unprognostic (1.32e-1)" "unprognostic (5.55e-2)" "unprognostic (2.26e-1)" "unprognostic (1.53e-1)" "unprognostic (3.68e-3)" "unprognostic (3.42e-1)" "unprognostic (2.42e-1)" "unprognostic (9.24e-2)" 2.5 8.3 2.9 6.0 3.2 3.9 4.5 4.6 3.4 3.2 6.0 6.6 6.2 3.5 5.6 4.9 5.8 2.8 3.4 2.4 5.8 4.4 5.8 3.3 10.2 3.3 3.3 4.4 5.8 7.7 3.7 3.6 3.5 4.8 7.4 7.0 6.0 3.1 3.7 5.1 6.8 3.3 3.2 6.4 6.2 8.9 3.8 10.2 6.0 3.9 9.6 3.6 2.4 3.8 25.2 14.9 33.6 12.4 5.5 7.7 33.9 24.1 13.6 20.7 19.4 7.5 17.0 55.4 8.5 12.4 21.7 36.9 22.0 12.3 25.3 29.2 6.1 23.0 12.1 11.8 7.7 42.6 23.1 7.4 7.8 17.6 12.6 6.7 11.1 28.2 16.7 26.3 23.2 18.1 54.4 17.4 31.3 31.6 15.7 47.8 33.9 21.0 10.8 10.4 30.4 19.3 21.3 18.6 9.8 15.4 19.4 20.8 6.6 22.9 14.7 23.2 20.1 11.6 25.6 20.2 14.6 19.7 26.4 14.2 4.5 8.8 1.8 5.5 2.2 2.8 2.1 1.9 7.2 2.6 2.2 2.5 7.8 2.8 6.5 2.2 3.0 2.6 2.9 3.2 4.6 3.4 2.4 5.8 3.3 3.3 3.5 3.2 3.8 3.8 5.4 9.6 5.1 10.1 5.9 2.7 3.2 4.3 4.0 4.1 4.3 3.3 8.5 2.8 9.0 1.8 4.2 7.9 2.1 6.1 5.9 5.5 70.0 13.9 6.5 3.8 6.7 24.4 7.1 3.0 16.2 3.3 8.2 10.2 4.5 9.0 5.0 13.3 8.1 10.1 11.2 9.8 0.0 10.7 4.3 62.1 2.1 7.4 12.4 8.4 8.5 7.7 5.2 26.2 12.6 2.7 5.6 2.2 7.8 4.2 8.9 4.9 11.1 5.2 0.0 3.3 3.4 34.0 22.6 6.9 4.8 4.2 4.4 7.7 10.1 2.4 RMND5B "FLJ22318, GID2, GID2B" ENSG00000145916 "Required for meiotic nuclear division 5 homolog B" Q96G75 5 178130996-178150568 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 186.6;Late spermatids: 415.4;Spermatocytes: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 130.3;MCF7: 185.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047778 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA047778: AB_2680153" "unprognostic (2.08e-1)" "unprognostic (6.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.35e-2)" "unprognostic (4.38e-2)" "unprognostic (9.81e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.48e-1)" "prognostic favorable (7.66e-4)" "unprognostic (1.60e-1)" "prognostic favorable (7.22e-8)" "unprognostic (1.77e-2)" "unprognostic (1.41e-1)" "unprognostic (6.43e-2)" "unprognostic (5.78e-2)" 18.9 23.4 19.8 11.2 19.7 13.2 18.8 19.2 20.3 24.0 19.4 24.5 13.2 22.7 12.2 69.8 19.2 9.6 28.1 19.7 18.7 22.4 27.2 17.4 18.0 22.3 19.4 17.1 25.4 23.5 20.7 16.4 19.1 19.0 11.4 10.5 24.2 15.9 45.6 29.6 17.3 15.9 19.6 19.2 23.2 81.6 21.2 23.7 20.5 32.4 23.0 22.1 28.2 20.9 21.3 37.5 21.4 53.5 27.4 2.8 71.3 16.9 18.2 25.1 29.2 42.1 30.2 44.6 32.9 11.9 27.6 27.6 21.5 36.7 8.8 130.3 28.7 46.8 39.1 22.8 29.0 21.9 16.3 5.9 27.1 17.3 27.3 14.0 25.5 14.7 40.1 28.8 8.1 185.2 15.5 12.5 29.5 25.9 20.4 19.7 15.8 31.6 21.1 32.4 22.5 32.2 22.8 73.0 40.3 17.3 56.9 29.5 17.7 13.9 21.9 12.8 21.3 42.4 43.4 37.0 18.2 21.2 19.6 21.8 16.5 42.5 6.5 20.1 2.8 18.3 13.0 7.3 8.8 24.9 20.4 11.3 11.4 4.2 27.2 13.7 22.4 12.4 19.8 19.7 19.2 20.3 19.7 18.7 22.3 19.4 19.1 19.6 21.2 20.9 13.5 12.8 6.9 7.8 20.5 9.6 20.6 15.3 14.2 48.6 19.3 16.1 22.2 27.1 12.2 31.3 52.1 31.7 8.0 17.6 23.5 21.0 186.6 7.8 10.2 13.3 9.0 28.0 15.4 19.1 29.8 16.7 23.0 10.5 5.1 16.4 15.0 14.0 21.7 48.8 16.6 15.0 28.5 15.0 9.6 415.4 28.9 10.5 7.2 10.3 22.7 30.9 14.4 8.5 14.1 19.1 13.3 25.2 14.8 20.6 26.1 21.6 7.3 61.4 13.1 17.5 16.3 133.0 35.7 28.9 13.4 44.5 10.9 18.5 17.9 20.0 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 RNASEH2A "AGS4, RNASEHI, RNHIA, RNHL" ENSG00000104889 "Ribonuclease H2 subunit A" O75792 19 12806584-12813640 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 62.3;Extravillous trophoblasts: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042692 Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA042692: AB_10793981" "unprognostic (6.74e-2)" "prognostic favorable (1.18e-4)" "prognostic favorable (6.18e-4)" "unprognostic (2.24e-1)" "unprognostic (2.62e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (8.48e-2)" "unprognostic (9.33e-2)" "prognostic favorable (1.22e-4)" "unprognostic (3.80e-3)" "unprognostic (8.71e-2)" "prognostic unfavorable (6.29e-6)" "unprognostic (3.40e-3)" "unprognostic (4.35e-2)" "unprognostic (5.35e-2)" "unprognostic (8.60e-2)" 8.9 6.8 7.0 11.8 7.2 28.0 9.0 10.4 9.1 10.8 6.2 10.5 10.3 8.5 4.9 18.3 10.6 4.9 7.6 7.2 6.1 7.4 6.9 7.3 17.1 7.3 6.5 8.9 9.2 5.3 5.4 10.4 7.4 6.0 10.7 8.4 8.6 5.0 8.9 13.9 10.0 8.2 6.0 14.5 9.4 19.8 6.8 24.4 7.5 6.6 18.7 8.2 10.8 9.5 130.0 103.8 94.8 75.7 12.3 23.4 76.2 68.4 40.0 126.3 136.0 76.2 58.7 126.9 106.2 36.6 59.6 79.4 82.6 89.2 83.5 82.7 118.1 67.7 112.9 89.9 7.1 70.6 60.5 10.4 19.7 110.7 43.9 21.4 47.3 114.8 91.2 46.8 82.0 251.4 132.8 83.0 56.4 79.1 167.4 146.1 102.0 113.7 39.6 63.8 119.8 76.7 67.0 39.8 46.7 39.8 76.1 78.4 29.3 129.2 55.7 197.0 126.1 97.6 130.3 108.5 77.4 129.4 105.5 9.4 19.1 17.2 23.9 27.6 23.3 36.8 19.6 22.5 19.0 36.3 15.9 19.6 4.4 44.8 27.7 21.0 25.8 19.1 7.0 7.2 10.4 9.1 7.2 6.1 7.3 6.5 7.4 6.0 6.8 9.5 5.3 0.0 2.6 1.3 15.3 14.0 15.7 22.9 6.8 16.2 2.8 11.7 2.7 12.8 7.6 0.0 4.2 62.3 9.1 11.3 0.0 5.4 16.1 0.8 1.6 9.0 8.4 38.7 2.2 6.0 117.4 10.3 10.7 1.1 3.8 2.5 11.7 4.4 48.9 8.4 3.0 13.9 22.4 9.1 13.2 18.8 8.4 9.3 12.4 1.9 8.5 10.4 14.4 1.0 2.4 2.1 6.8 4.9 33.0 5.3 6.2 1.0 9.5 13.9 6.6 15.6 9.8 51.2 44.9 23.8 13.2 22.7 10.2 0.8 24.8 16.1 RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30970984-30999911 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 63.3" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA021576: AB_1856331, HPA052404: AB_2681817" "unprognostic (1.13e-1)" "unprognostic (1.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-2)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (6.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (4.47e-1)" 20.9 12.9 11.1 13.5 12.5 11.6 18.6 11.2 14.2 16.0 15.1 17.5 13.6 13.3 16.5 22.4 15.7 9.6 8.5 10.4 11.3 21.6 8.6 15.5 13.9 13.9 13.2 12.6 13.5 16.8 5.6 18.1 12.4 14.0 18.0 2.3 15.2 15.2 7.4 26.2 13.9 13.7 12.8 25.8 11.9 5.1 16.4 7.9 15.8 10.1 12.6 14.8 17.3 13.8 12.7 25.6 1.5 25.4 34.0 28.5 22.7 9.7 14.9 9.4 8.4 0.0 9.4 11.5 14.8 19.0 17.0 17.0 13.2 12.1 7.8 10.0 5.6 4.8 8.1 0.0 24.3 12.8 10.7 27.7 63.3 10.1 33.5 16.1 15.8 0.0 0.0 34.9 15.6 17.0 0.1 13.5 10.5 25.7 14.4 27.9 0.0 39.2 13.6 18.2 9.8 0.5 14.9 5.9 14.9 16.6 39.4 20.2 13.3 0.0 3.5 15.6 11.5 0.4 1.3 7.3 16.5 22.1 13.3 25.3 61.6 31.3 12.8 57.3 7.2 28.4 6.8 6.8 46.4 28.4 3.7 6.2 54.0 13.9 70.2 17.1 10.1 29.2 11.1 12.5 11.2 14.2 10.4 11.3 13.9 13.2 12.4 12.8 16.4 13.8 14.1 3.2 5.9 7.8 14.1 9.3 13.4 16.8 22.2 0.1 13.1 15.0 4.0 7.2 7.8 11.0 0.0 47.5 10.5 23.4 29.4 9.9 0.4 14.5 12.8 13.2 4.9 11.2 0.8 18.6 37.1 13.2 5.6 12.4 1.3 14.1 25.4 2.7 51.1 0.0 1.0 12.0 8.2 73.9 8.4 1.6 16.8 35.5 16.0 26.2 45.3 3.9 19.6 9.0 0.7 11.9 13.1 15.4 9.0 22.2 27.5 49.3 10.4 0.6 26.3 8.2 14.2 0.7 4.0 24.1 14.6 43.6 7.5 10.6 14.6 11.2 RNF185 FLJ38628 ENSG00000138942 "Ring finger protein 185" Q96GF1 22 31160182-31207019 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.33e-1)" "unprognostic (3.65e-3)" "unprognostic (4.76e-3)" "unprognostic (2.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.97e-1)" "unprognostic (2.56e-1)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "prognostic favorable (4.82e-5)" "unprognostic (3.04e-1)" "unprognostic (1.63e-1)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" 19.8 18.7 21.5 14.4 22.5 10.1 22.8 21.7 25.1 22.3 22.5 23.4 20.5 22.5 25.1 25.9 23.0 16.4 21.1 22.5 22.1 36.2 48.4 19.0 16.2 21.7 22.0 26.1 19.2 48.8 15.8 21.0 22.0 38.2 22.2 16.5 30.2 28.7 23.4 29.9 21.9 25.6 21.9 16.6 21.7 10.8 23.2 21.0 52.0 25.5 21.3 24.2 23.0 23.6 23.7 13.8 26.1 29.9 51.8 34.5 24.9 27.7 53.3 37.2 50.2 15.6 11.1 22.5 15.2 49.3 32.8 14.6 25.3 28.6 38.1 22.6 27.5 9.8 13.2 19.1 72.5 24.1 14.6 37.1 100.8 26.2 60.2 34.0 31.7 23.5 11.7 26.2 45.2 16.8 20.8 13.5 11.7 48.8 15.2 21.1 26.1 26.5 27.0 20.4 11.6 23.4 20.2 26.5 41.0 26.7 18.4 15.8 22.2 26.1 18.7 30.9 13.6 36.2 31.6 28.4 34.5 15.1 21.4 16.9 15.7 9.0 12.2 15.8 13.6 10.0 12.4 13.8 13.3 8.2 12.5 11.5 22.3 16.9 13.7 4.9 14.6 14.8 21.5 22.5 21.7 25.1 22.5 22.1 21.7 22.0 22.0 21.9 23.2 23.6 9.3 22.4 12.6 10.7 8.8 9.1 10.3 10.0 9.6 11.0 14.2 10.8 5.5 20.0 11.5 18.4 8.4 13.0 11.3 16.4 21.5 15.1 19.0 8.9 8.2 8.5 16.8 5.0 14.0 14.9 23.2 10.9 8.2 10.3 5.7 8.4 23.2 28.9 14.2 8.4 17.3 15.8 14.2 8.8 7.5 18.3 7.5 10.5 8.8 10.3 10.7 11.9 7.2 13.6 22.5 15.5 12.7 15.8 6.8 14.5 17.7 22.9 12.4 7.8 6.6 9.5 9.3 7.4 9.8 10.6 10.7 37.2 7.2 6.0 7.8 9.8 RNF187 "RACO-1, RACO1" ENSG00000168159 "Ring finger protein 187" Q5TA31 1 228487382-228496188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/70: 189.0" "Low region specificity" "Detected in all" HPA030098 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA030098: AB_10602923" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (2.83e-4)" "unprognostic (4.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.93e-2)" "unprognostic (3.46e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (5.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.92e-3)" "unprognostic (1.59e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" 26.8 66.6 16.2 7.5 16.2 11.3 25.8 14.8 24.3 40.5 3.4 28.1 8.6 31.8 4.3 59.1 28.7 5.6 35.4 15.9 16.9 40.7 52.0 23.6 7.3 19.4 15.2 39.3 34.5 22.5 47.7 5.5 18.4 33.5 3.7 9.0 39.7 8.2 64.2 45.0 22.5 5.6 15.6 37.0 27.6 20.8 18.5 8.5 36.1 19.8 6.1 29.9 41.2 19.8 26.7 23.1 14.8 28.9 16.8 12.5 26.6 21.5 17.3 15.6 12.7 12.8 19.2 65.9 43.1 28.9 11.4 20.9 19.1 22.1 5.8 25.9 28.5 20.8 13.2 12.6 46.1 22.1 34.4 20.4 44.7 11.6 15.8 18.3 14.0 52.6 35.6 115.2 12.4 17.7 35.2 20.8 30.7 19.1 24.0 27.8 12.5 61.5 11.4 17.2 29.9 30.0 21.9 44.1 62.3 4.3 34.6 50.2 27.8 18.3 16.9 19.6 19.3 189.0 56.7 36.4 46.7 22.7 28.7 0.0 0.5 3.6 0.6 1.0 0.7 0.5 0.7 1.0 0.6 1.0 0.6 0.7 0.1 0.4 1.4 0.7 0.6 0.3 16.2 16.2 14.8 24.3 15.9 16.9 19.4 15.2 18.4 15.6 18.5 19.8 54.0 25.6 15.5 8.1 47.2 36.2 42.9 10.6 38.7 85.2 59.5 58.5 70.8 65.8 14.2 40.5 18.8 19.7 52.2 39.8 113.5 15.2 0.8 35.5 47.2 32.1 40.0 118.4 16.6 24.5 27.1 54.4 34.7 32.0 44.5 45.0 41.7 67.4 27.4 55.5 17.2 36.6 2.0 40.1 30.5 4.2 24.5 35.8 39.2 12.2 29.7 145.3 62.8 7.1 12.6 21.4 23.4 25.9 35.4 44.0 32.9 126.4 10.3 47.7 19.7 52.2 38.4 4.2 21.5 57.0 55.3 17.6 54.6 217.5 38.6 31.7 RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58353676-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.7;Intestinal goblet cells: 41.6;Undifferentiated cells: 63.6" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 41.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 17.0;CACO-2: 24.7;Hep G2: 49.4;OE19: 54.7" HPA008079 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favorable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" 0.2 10.9 1.7 2.0 3.1 0.7 5.5 9.6 2.7 2.6 1.5 13.4 22.7 1.7 4.4 10.4 4.8 2.7 2.7 2.0 1.3 6.1 9.1 3.6 0.4 1.8 3.4 0.9 8.2 5.2 4.3 4.8 1.9 9.4 19.3 1.2 9.3 4.8 0.3 11.3 16.9 0.6 1.4 0.5 5.8 3.4 2.3 3.7 1.9 0.0 1.5 2.1 5.2 1.4 1.1 17.0 2.7 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 24.7 8.2 0.0 8.5 0.0 1.9 4.6 0.6 6.8 0.0 8.6 11.3 1.9 0.8 49.4 0.0 0.2 0.1 0.0 13.4 0.0 2.1 0.0 0.0 0.2 0.2 0.4 0.0 0.2 0.1 0.2 0.4 54.7 1.0 0.3 0.0 2.2 5.9 9.0 1.6 0.1 1.6 0.7 0.5 5.4 2.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.4 0.1 0.3 0.0 3.8 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.2 0.0 1.7 3.1 9.6 2.7 2.0 1.3 1.8 3.4 1.9 1.4 2.3 1.4 0.3 3.2 8.9 29.0 2.5 9.6 17.5 14.1 67.7 2.5 17.3 13.6 4.0 17.2 5.8 18.4 2.1 26.0 2.2 33.0 15.6 5.3 1.2 14.6 1.1 1.8 15.5 0.8 1.8 2.7 3.1 0.7 9.7 12.7 0.0 7.2 0.7 11.9 2.6 5.0 1.3 41.6 12.2 0.8 0.9 1.5 0.3 1.3 14.2 4.7 2.8 12.0 10.3 0.0 0.7 6.2 21.1 0.4 1.0 9.9 28.7 2.9 5.6 2.8 0.0 0.5 1.1 1.0 0.8 28.4 6.1 5.9 3.1 0.4 63.6 6.3 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179759-11348330 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 280.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 710000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 36.4 9.3 6.7 13.5 16.3 6.8 22.3 19.1 14.3 18.7 0.8 22.6 16.7 22.0 10.3 16.2 13.6 15.6 17.0 12.1 3.5 14.5 16.5 16.9 10.1 1.7 4.4 19.0 11.7 12.8 5.9 24.9 1.4 17.4 26.2 13.5 14.6 18.1 30.4 8.5 19.2 27.9 2.0 16.4 14.1 7.8 6.4 8.4 13.9 28.9 8.8 21.1 11.0 10.4 17.5 41.7 33.8 33.2 59.7 41.6 21.6 40.4 37.7 25.8 27.1 39.8 37.2 21.9 23.4 64.5 31.3 18.9 24.7 23.4 40.6 31.2 14.7 43.8 70.6 79.7 21.4 24.7 12.1 32.6 14.6 31.9 22.6 21.0 42.0 11.9 38.6 8.6 38.8 14.8 18.2 12.7 18.8 36.9 25.3 21.7 74.2 7.0 14.0 48.8 15.9 16.9 79.6 27.4 27.4 25.5 11.3 13.6 57.3 52.9 38.2 21.2 36.0 6.8 8.9 18.8 22.8 28.2 75.4 0.9 0.4 0.4 0.6 0.4 0.7 0.3 0.4 0.4 0.3 0.5 0.4 0.4 0.6 0.8 0.4 0.6 0.4 0.2 6.7 16.3 19.1 14.3 12.1 3.5 1.7 4.4 1.4 2.0 6.4 10.4 114.5 115.4 79.1 81.3 16.0 39.9 43.0 15.3 21.1 35.7 33.5 41.1 107.0 37.1 53.1 22.0 58.4 26.3 20.4 97.7 1.9 27.1 11.0 53.6 141.2 90.3 21.2 22.5 280.4 39.5 19.1 64.0 18.3 55.3 29.0 36.9 56.0 43.1 19.6 80.8 158.1 92.2 10.2 20.3 27.0 4.9 43.8 30.4 23.2 107.7 20.6 38.4 15.5 99.0 66.9 39.1 43.6 78.6 16.2 53.5 45.3 15.7 32.7 48.5 131.5 70.0 118.5 30.3 24.6 19.9 27.8 31.5 18.5 34.2 54.8 40.7 ROGDI FLJ22386 ENSG00000067836 "Rogdi atypical leucine zipper" Q9GZN7 16 4796968-4802880 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amelogenesis imperfecta, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 105.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 179.2;Rod photoreceptor cells: 149.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 74.6;intermediate monocyte: 62.7;myeloid DC: 61.5;non-classical monocyte: 61.8;plasmacytoid DC: 34.5" "Group enriched" "Detected in all" 6 "dendritic cells: 61.5;monocytes: 74.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041000 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" "HPA041000: AB_10794077" "unprognostic (1.74e-3)" "unprognostic (1.98e-3)" "unprognostic (1.25e-1)" "unprognostic (1.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.95e-1)" "unprognostic (3.13e-1)" "unprognostic (3.79e-3)" "unprognostic (3.22e-2)" "unprognostic (1.21e-1)" "prognostic favorable (9.71e-4)" "unprognostic (5.24e-2)" "prognostic favorable (2.67e-5)" "unprognostic (1.71e-1)" "unprognostic (7.16e-2)" "unprognostic (2.17e-1)" "unprognostic (3.08e-2)" 7.5 24.1 82.9 11.6 84.5 78.0 7.3 81.3 105.6 8.8 64.3 17.6 24.8 7.5 6.6 18.1 14.5 14.4 44.2 91.4 83.9 19.3 19.7 15.5 8.6 84.0 84.9 5.9 22.9 26.4 18.2 7.9 80.9 19.0 7.6 61.9 25.3 16.6 63.1 6.5 21.4 11.3 79.4 15.6 21.1 8.2 96.8 10.1 4.6 32.9 8.7 11.2 6.4 97.6 13.5 18.8 9.5 42.4 12.2 6.2 36.4 9.4 4.6 8.2 3.6 12.5 15.3 5.9 15.1 19.9 5.3 26.7 9.9 28.7 3.2 4.8 13.3 8.0 28.9 28.1 19.8 10.4 6.5 8.3 11.7 12.4 8.3 21.6 14.5 11.5 5.7 3.5 14.1 74.9 9.4 51.0 15.3 15.4 14.2 30.1 26.1 30.1 19.8 18.1 55.3 24.5 38.6 42.4 9.9 11.9 50.9 40.8 22.3 7.3 17.0 52.5 6.5 14.2 17.0 5.2 8.6 40.0 6.5 10.5 74.6 8.1 2.1 62.7 6.6 2.5 5.4 4.9 61.5 2.8 4.7 5.5 6.7 6.7 61.8 34.5 6.1 38.0 82.9 84.5 81.3 105.6 91.4 83.9 84.0 84.9 80.9 79.4 96.8 97.6 7.0 19.2 7.8 17.3 6.7 5.1 28.0 84.4 32.5 179.2 23.0 22.5 58.1 21.5 36.7 27.6 110.5 46.9 11.5 23.4 39.2 22.2 30.3 17.6 8.5 12.0 52.0 38.7 33.2 16.0 73.4 15.9 11.7 7.2 5.7 9.8 24.3 19.7 64.8 25.2 19.2 29.7 69.2 28.7 29.0 57.0 6.8 31.0 12.4 10.3 77.0 102.5 6.2 7.5 90.2 13.5 23.7 19.2 4.6 12.7 65.7 80.8 21.3 149.7 6.6 8.2 15.3 6.5 20.7 24.8 5.8 30.6 9.5 64.7 23.1 22.3 RPS18 "D6S218E, HKE3, KE-3, KE3, S18" ENSG00000231500 "Ribosomal protein S18" P62269 6 33272075-33276511 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast myoepithelial cells: 26385.3;Suprabasal keratinocytes: 31942.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050159, HPA055007" Approved Supported Cytosol NA NA 120000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA050159: AB_2681035, HPA055007: AB_2682668" "prognostic favorable (9.81e-4)" "unprognostic (1.76e-1)" "unprognostic (2.67e-1)" "unprognostic (7.74e-2)" "unprognostic (4.00e-2)" "unprognostic (3.95e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.67e-1)" "unprognostic (4.63e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.15e-10)" "unprognostic (7.00e-2)" "unprognostic (4.00e-2)" "unprognostic (2.85e-1)" "unprognostic (9.19e-2)" 3268.2 2353.2 1862.8 2097.6 1883.3 6071.7 6110.7 1827.2 2345.5 3989.9 1782.7 3060.6 2024.5 2386.7 2877.9 4570.6 3069.7 1608.3 1778.5 1806.3 1863.3 2052.0 2248.2 2034.3 4842.9 1889.4 1840.1 6497.6 5554.4 1294.1 1412.1 1956.1 1895.2 2780.5 2977.4 697.1 3045.6 1415.3 2861.9 6539.3 2565.0 1891.5 1948.2 3087.2 2634.1 789.9 1920.2 3097.1 2084.7 2140.2 4485.9 3011.2 3685.5 1926.5 4603.2 2645.2 3377.1 8930.5 5769.4 11474.6 5486.7 4471.1 6678.3 5939.4 4461.0 6787.2 2617.5 15106.6 4694.9 4890.5 2759.3 3293.1 5472.9 7251.7 4665.1 4722.4 8590.2 5617.0 2868.6 9108.9 11226.3 9771.0 2849.3 12386.6 14318.8 4498.5 13349.4 5436.5 5770.2 4373.8 7686.7 4590.7 5362.0 7880.9 4994.9 10924.1 4652.3 5367.0 3798.3 5853.7 5446.7 10293.5 5524.1 6007.1 3902.3 5714.2 1754.6 8884.0 14781.0 2429.4 6105.7 16713.0 4642.3 2714.4 3129.5 2894.4 5978.6 5376.3 12310.7 11828.5 1512.3 10665.4 3350.2 578.7 1878.9 236.8 2362.1 1653.6 4023.7 5634.6 4545.5 3382.7 3273.4 4515.8 4968.4 4374.8 184.7 3177.0 1265.3 2962.7 3727.6 9405.4 1862.8 1883.3 1827.2 2345.5 1806.3 1863.3 1889.4 1840.1 1895.2 1948.2 1920.2 1926.5 4065.5 1480.8 2569.4 9.4 8276.1 20537.2 16151.5 18150.8 5757.2 343.9 19342.8 26385.3 596.5 4185.0 6755.1 1841.0 231.4 8761.7 5535.7 2348.6 5106.4 4750.1 1164.5 1985.2 7580.0 5826.2 3089.9 3782.1 7.5 12662.2 14558.3 4617.6 2073.4 3457.9 3051.1 5393.6 6329.9 4513.1 6281.1 159.9 8.1 7793.0 4418.8 6115.9 12428.1 3197.4 9895.8 4296.2 8448.8 13.1 6356.1 1521.4 4753.9 5.0 11.5 8283.0 5985.7 4056.9 3499.7 14221.0 5563.4 5974.5 1936.4 683.4 2005.0 7010.5 6802.2 773.3 1827.1 8678.7 31942.8 8778.2 6742.0 7987.5 9896.2 16152.8 RPS6KA2 "HU-2, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 399.6;Excitatory neurons: 204.1;Horizontal cells: 287.7;Inhibitory neurons: 552.3;Oligodendrocyte precursor cells: 244.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 26.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "eosinophil: 22.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.4" "Cell line enhanced" "Detected in many" "ASC diff: 214.5;ASC TERT1: 156.1;HHSteC: 158.5;HSkMC: 141.4;hTERT-HME1: 173.0;hTERT-RPE1: 316.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: AB_2679203, HPA054237: AB_2682425" "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favorable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 34.2 9.0 40.3 8.0 41.0 10.5 27.8 35.0 35.2 18.1 8.6 16.6 6.1 26.0 7.1 20.1 18.7 18.2 61.8 37.8 42.1 13.6 6.6 45.1 7.5 48.3 41.7 29.2 19.4 49.6 27.2 17.9 42.0 14.9 10.3 28.9 14.7 14.2 24.1 16.4 16.5 22.7 35.3 26.0 21.4 7.7 47.3 5.9 36.3 30.5 7.3 24.5 14.9 49.3 9.1 0.0 17.9 26.0 214.5 156.1 0.4 19.3 37.4 10.6 14.6 0.0 5.8 1.1 6.2 68.2 8.4 8.2 9.4 41.8 9.4 4.2 2.3 0.1 40.2 0.4 158.5 0.6 7.2 141.4 29.4 56.6 173.0 316.2 58.0 19.2 0.2 0.2 43.6 1.9 0.8 2.1 4.5 9.1 10.5 3.0 9.2 27.3 11.1 10.1 9.8 68.8 6.7 17.9 24.8 4.4 0.5 14.3 21.7 37.3 3.7 103.8 5.6 5.2 8.4 2.6 24.8 1.2 36.0 0.2 0.6 22.4 0.6 0.8 0.3 0.3 0.6 0.3 0.8 0.5 0.7 0.3 0.5 4.4 2.2 4.7 0.5 0.4 40.3 41.0 35.0 35.2 37.8 42.1 48.3 41.7 42.0 35.3 47.3 49.3 60.9 22.4 46.2 399.6 2.7 4.7 5.4 4.6 3.4 37.1 7.1 5.0 60.0 15.7 11.6 36.8 8.4 0.2 8.0 1.9 11.7 15.2 14.8 20.6 4.6 58.2 5.4 0.0 204.1 24.0 0.3 16.3 16.8 20.3 2.5 10.5 45.3 11.9 7.2 287.7 552.3 5.3 2.0 6.0 6.7 69.3 5.3 8.0 19.6 144.3 3.5 10.1 1.0 244.8 97.7 26.8 1.7 4.5 2.4 9.9 0.3 7.0 9.4 17.1 13.1 10.0 14.5 3.5 2.3 1.2 3.4 0.3 2.0 9.5 1.4 6.6 RSPH14 RTDR1 ENSG00000100218 "Radial spoke head 14 homolog" Q9UHP6 22 23059415-23145021 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 25.0" "Group enriched" "Detected in many" 6 "Early spermatids: 139.7;Late spermatids: 252.0" "Cancer enhanced" "Detected in some" "renal cancer: 2.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 7.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 7.7" "Cell line enhanced" "Detected in some" "GAMG: 3.2;RPTEC TERT1: 4.2;U-266/70: 4.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA018420, HPA050425" Approved Uncertain Nucleoli NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoli "HPA018420: AB_1856496, HPA050425: " "unprognostic (8.81e-2)" "unprognostic (1.57e-2)" "unprognostic (1.15e-3)" "unprognostic (3.80e-3)" "unprognostic (1.97e-1)" "unprognostic (1.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.41e-1)" "unprognostic (1.22e-2)" "unprognostic (8.31e-2)" "unprognostic (7.28e-2)" "prognostic favorable (4.04e-4)" "unprognostic (5.18e-2)" "unprognostic (4.40e-2)" "unprognostic (3.16e-1)" "unprognostic (7.73e-2)" 0.3 2.0 7.7 0.2 9.4 0.2 0.4 5.9 11.8 1.0 9.4 0.6 0.2 0.8 3.5 0.4 12.4 1.3 0.4 8.3 9.9 7.3 0.4 1.5 0.2 8.6 10.9 3.9 0.9 2.4 3.7 0.1 7.7 0.8 0.2 11.4 0.6 1.7 0.7 1.1 0.3 0.3 7.6 0.5 0.7 25.0 7.2 0.1 1.9 0.1 0.2 0.2 0.4 9.5 0.2 2.5 1.9 2.0 0.0 0.9 0.1 0.0 0.5 0.4 0.4 0.4 0.7 0.5 0.7 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.1 0.1 1.0 0.0 0.2 0.4 0.0 1.2 0.0 0.8 0.0 1.0 0.0 0.3 0.3 0.4 0.0 0.6 0.0 0.1 0.0 2.0 4.2 0.0 2.7 0.9 0.0 0.0 0.1 0.1 0.3 0.5 0.0 1.5 0.5 0.1 0.0 4.9 1.9 1.6 1.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 7.7 0.1 1.8 0.0 0.0 0.6 7.7 9.4 5.9 11.8 8.3 9.9 8.6 10.9 7.7 7.6 7.2 9.5 1.9 0.0 0.0 2.0 0.0 0.0 0.9 0.0 0.0 1.1 0.2 0.5 0.1 1.5 3.7 0.0 4.2 0.0 0.2 0.0 7.9 1.0 139.7 17.8 0.5 0.4 0.0 0.0 3.5 0.2 0.0 0.5 0.0 0.5 0.0 1.2 0.7 0.0 0.1 11.8 2.8 0.1 0.0 0.0 0.0 252.0 2.1 0.3 0.0 0.0 0.0 4.6 0.0 1.0 1.1 0.4 0.0 1.9 0.1 0.2 0.0 17.7 29.2 5.1 0.0 0.8 0.9 29.4 8.3 0.0 0.0 0.0 0.4 2.8 0.1 0.3 RTN4RL2 "NgR2, NGRH1" ENSG00000186907 "Reticulon 4 receptor like 2" Q86UN3 11 57460528-57477534 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 39.1;liver: 40.7;thyroid gland: 30.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.9;Cholangiocytes: 12.8;Excitatory neurons: 16.7;Hepatocytes: 14.0;Oligodendrocyte precursor cells: 9.5;Spermatocytes: 10.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 44.1;Karpas-707: 67.5;REH: 42.3;RPMI-8226: 134.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "amygdala: 13.5;cerebral cortex: 23.8;hippocampal formation: 21.0" "Intracellular and membrane" NA NA 27000000 "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (6.27e-3)" "unprognostic (2.02e-2)" "unprognostic (4.57e-2)" "unprognostic (8.40e-2)" "unprognostic (8.51e-2)" "unprognostic (7.64e-2)" "unprognostic (6.83e-2)" "unprognostic (3.72e-2)" "unprognostic (7.27e-2)" "unprognostic (2.41e-1)" "unprognostic (1.09e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (3.05e-7)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" "unprognostic (5.16e-3)" "unprognostic (2.18e-2)" 4.1 0.7 19.0 0.3 39.1 0.8 3.5 0.0 27.3 2.1 0.0 1.0 1.1 2.0 0.2 1.6 1.7 3.0 3.3 25.2 0.0 2.8 40.7 2.6 0.4 0.0 0.0 1.1 2.4 3.7 3.6 1.9 0.0 1.6 0.1 1.0 3.4 0.3 1.7 4.3 1.1 0.7 0.0 1.0 1.5 1.8 0.0 1.9 30.5 0.4 0.3 1.2 1.6 8.2 7.4 10.1 7.6 13.1 3.1 4.4 1.0 0.1 2.9 0.3 2.7 1.3 1.4 0.2 0.2 0.4 4.3 0.2 11.9 0.2 0.1 1.7 4.7 2.3 1.1 7.2 4.4 1.7 44.1 11.9 1.3 1.1 1.1 1.3 0.1 12.9 1.6 67.5 0.1 1.4 0.2 5.3 13.3 0.5 7.6 42.3 5.4 134.0 0.1 0.2 14.0 1.2 1.1 0.6 7.7 0.6 8.5 2.0 0.1 0.5 22.7 3.1 2.4 4.1 9.2 1.4 16.7 7.3 5.8 0.0 0.3 0.0 0.0 0.6 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 19.0 39.1 0.0 27.3 25.2 0.0 0.0 0.0 0.0 0.0 0.0 8.2 1.7 0.0 0.0 2.0 0.4 5.7 0.4 0.3 2.8 19.9 2.1 1.5 0.4 12.8 0.1 0.0 0.0 0.0 0.9 0.2 3.9 1.3 2.6 0.6 0.9 2.1 1.8 0.8 16.7 0.6 5.5 1.6 0.5 2.1 0.0 0.0 1.1 14.0 0.4 0.0 1.1 0.6 0.0 0.0 2.1 1.3 0.3 0.6 1.8 3.7 0.5 0.8 2.1 9.5 1.2 0.8 0.1 1.2 0.0 1.0 0.0 1.1 0.0 1.4 6.6 1.0 5.4 10.2 1.7 1.1 2.8 0.0 0.9 0.1 0.2 0.2 RUFY1 "FLJ22251, RABIP4, ZFYVE12" ENSG00000176783 "RUN and FYVE domain containing 1" Q96T51 5 179550554-179610012 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038804 Approved Supported "Nuclear speckles,Vesicles,Cytosol" NA NA 25000 "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Vesicles, Cytosol" "Nuclear speckles" "HPA038804: AB_10673290" "unprognostic (3.17e-2)" "unprognostic (2.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.50e-1)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (9.74e-2)" "unprognostic (1.31e-1)" "unprognostic (2.73e-2)" "unprognostic (3.60e-1)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" "unprognostic (5.85e-2)" 28.2 33.1 9.6 13.4 10.5 13.3 26.1 9.8 10.2 27.2 11.3 29.1 9.4 27.5 8.1 33.9 24.5 8.8 20.4 9.5 10.1 24.1 21.3 26.6 14.2 10.2 10.0 23.9 24.4 13.5 22.7 9.0 10.1 22.4 8.2 7.4 25.8 8.6 33.8 33.1 25.9 7.8 9.9 35.2 24.2 10.9 10.0 13.6 24.7 10.1 11.5 26.3 27.2 10.6 13.9 22.5 11.8 15.7 22.3 18.2 13.4 24.2 17.2 14.1 16.3 22.0 31.6 22.4 13.4 29.6 16.2 12.6 21.9 31.6 16.4 71.2 16.6 39.2 17.1 16.0 22.8 22.0 20.7 18.5 17.1 9.5 27.0 24.6 15.5 12.5 16.2 20.8 12.7 42.0 23.5 15.2 12.6 15.0 10.5 20.9 8.4 20.9 23.5 22.4 11.7 16.7 35.4 22.5 13.2 14.8 18.0 26.6 18.8 18.3 6.2 10.0 19.3 12.8 21.2 39.8 16.9 39.0 17.2 14.9 4.8 11.9 2.2 5.1 1.3 3.8 2.7 2.3 4.2 5.7 1.9 2.4 7.9 1.8 7.1 4.8 4.5 29.8 9.6 10.5 9.8 10.2 9.5 10.1 10.2 10.0 10.1 9.9 10.0 10.6 19.8 35.3 30.8 30.0 23.6 10.3 11.5 11.7 16.5 9.3 17.8 17.5 22.8 28.6 23.1 14.7 20.9 21.7 15.7 20.0 9.8 19.7 8.0 28.2 21.9 20.9 10.8 27.7 31.8 14.4 15.8 19.7 19.9 20.0 29.8 20.4 12.5 14.1 31.1 11.8 28.4 17.5 8.2 30.7 21.0 3.4 23.0 137.2 10.6 21.5 43.7 11.9 15.5 23.1 33.9 22.1 18.5 27.1 18.3 14.2 14.1 34.0 32.8 12.0 6.6 20.8 17.8 11.1 8.4 21.9 11.4 21.2 19.5 25.0 15.3 10.2 RUNX2 "AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1" ENSG00000124813 "RUNX family transcription factor 2" Q13950 6 45328157-45664349 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 10.7" "Cell type enhanced" "Detected in many" "dendritic cells: 55.8;Early spermatids: 128.3;Inhibitory neurons: 95.2;Microglial cells: 128.4;Plasma cells: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 22.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 39.3;Karpas-707: 62.3;RH-30: 51.8;U-698: 55.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008374, HPA022040, CAB062561, CAB068226, HPA070715" Enhanced Enhanced Nucleoplasm No No "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB008374: AB_590789, CAB062561: AB_2665599, CAB068226: AB_2665598, HPA022040: AB_1846086, HPA070715: " "unprognostic (1.49e-1)" "unprognostic (8.90e-3)" "unprognostic (3.99e-2)" "unprognostic (2.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-1)" "unprognostic (1.23e-1)" "unprognostic (3.70e-2)" "unprognostic (3.18e-1)" "prognostic unfavorable (3.97e-9)" "prognostic unfavorable (2.24e-4)" "unprognostic (5.52e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (6.66e-5)" 1.7 0.7 1.1 4.3 1.0 9.7 2.8 1.2 1.4 6.7 0.9 3.7 2.0 1.5 0.8 1.4 0.9 3.4 0.7 1.3 1.5 1.5 0.7 2.7 4.5 1.9 1.8 2.2 0.6 0.6 1.6 1.5 1.9 4.8 3.9 0.1 10.7 2.6 0.8 2.4 6.0 1.6 1.6 3.6 3.2 0.5 2.0 4.5 1.8 0.9 5.6 3.6 4.9 1.9 3.6 1.1 0.8 0.0 3.2 8.3 0.0 3.3 7.9 10.9 15.2 0.0 1.9 0.0 3.8 4.7 4.9 4.3 0.0 3.1 19.7 13.7 1.5 0.0 2.4 0.0 16.7 14.2 0.1 22.5 2.5 9.7 10.9 39.3 0.2 5.6 0.0 62.3 19.7 1.0 0.4 24.7 0.7 3.2 0.5 0.1 51.8 0.0 10.7 7.0 0.0 0.0 2.4 0.1 4.1 9.2 3.6 1.2 0.5 11.1 8.8 17.2 12.1 19.6 0.0 55.2 12.5 5.3 5.0 8.6 0.9 4.5 1.5 0.2 12.9 0.2 3.5 4.0 2.4 0.2 0.6 1.8 6.5 22.1 0.1 15.4 3.2 1.0 1.1 1.0 1.2 1.4 1.3 1.5 1.9 1.8 1.9 1.6 2.0 1.9 0.9 0.0 2.7 4.6 5.7 2.8 16.6 5.3 1.2 0.0 2.0 1.4 2.7 0.0 4.9 3.7 0.0 0.0 55.8 0.3 0.0 0.6 128.3 0.7 3.5 0.8 0.0 3.8 17.4 0.2 0.0 7.0 4.1 0.5 2.5 0.1 1.1 0.8 3.7 0.0 95.2 1.0 20.3 6.7 20.8 20.0 1.2 16.3 7.2 128.4 18.6 0.0 7.2 6.6 5.2 0.4 0.1 2.2 44.4 16.5 0.0 3.3 5.1 0.0 6.6 1.5 6.2 0.8 0.5 1.2 1.6 0.1 21.4 0.2 0.2 28.0 RUNX3 "AML2, CBFA3, PEBP2A3" ENSG00000020633 "RUNX family transcription factor 3" Q13761 1 24899511-24965121 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.8;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "dendritic cells: 336.4;Langerhans cells: 133.9;NK-cells: 251.3;Plasma cells: 87.1;T-cells: 215.4" "Cancer enhanced" "Detected in all" "melanoma: 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 124.9;Karpas-707: 155.6;SK-MEL-30: 92.4;U-266/70: 54.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004195, CAB025416, HPA059006" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" Cytosol "CAB025416: , HPA004195: , HPA059006: AB_2683877" "unprognostic (7.75e-3)" "unprognostic (6.51e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.42e-1)" "unprognostic (7.60e-2)" "unprognostic (1.81e-2)" "unprognostic (6.51e-2)" "unprognostic (6.95e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "prognostic unfavorable (5.59e-5)" "unprognostic (1.10e-1)" "unprognostic (4.42e-2)" "unprognostic (3.08e-1)" "unprognostic (1.62e-1)" 3.5 1.4 3.7 21.1 3.6 68.8 3.5 3.8 4.6 19.7 3.7 3.7 5.0 1.6 0.7 2.6 1.6 5.3 1.1 3.6 3.8 1.6 3.7 9.5 34.7 4.7 4.4 0.6 0.9 0.4 0.7 0.9 4.3 1.9 4.2 0.1 4.7 0.8 3.8 11.5 15.0 1.6 4.1 35.1 5.5 2.3 4.3 11.2 1.8 0.7 29.0 6.5 1.5 4.5 0.3 10.4 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.5 0.0 0.5 0.0 19.3 18.4 16.4 0.1 0.4 11.1 0.0 0.7 124.9 1.9 0.4 1.8 0.1 0.0 4.5 42.8 0.1 0.0 0.0 1.1 0.0 0.0 3.1 0.1 155.6 0.0 0.0 1.5 37.9 0.7 0.0 3.2 0.0 0.1 22.7 0.0 0.5 3.5 0.0 7.3 0.1 92.4 2.9 0.0 25.7 0.0 0.0 1.9 0.0 0.5 54.6 40.4 18.2 0.1 42.0 4.4 0.7 1.1 7.0 21.7 4.5 11.3 6.7 7.9 18.7 1.4 5.7 3.9 14.6 1.3 28.7 7.7 1.5 9.2 5.5 3.7 3.6 3.8 4.6 3.6 3.8 4.7 4.4 4.3 4.1 4.3 4.5 4.4 0.0 3.6 0.0 57.7 7.6 0.8 4.6 2.2 0.0 9.8 11.3 2.4 0.0 1.5 1.8 0.0 0.1 336.4 0.5 0.0 0.2 2.3 1.1 1.2 2.4 0.0 13.7 0.0 0.2 0.1 3.3 13.3 2.3 45.2 0.0 2.2 1.5 4.6 0.0 0.0 0.5 0.0 22.9 133.9 1.0 0.0 55.6 46.2 1.0 51.1 0.0 251.3 0.0 0.1 0.1 0.1 0.7 87.1 1.2 0.0 0.3 0.5 0.0 0.0 3.5 3.6 0.3 4.1 2.3 5.8 0.3 215.4 0.1 0.4 0.4 S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3719.5;vagina: 1174.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2340.8;Paneth cells: 1098.9;Proximal enterocytes: 1549.1;Squamous epithelial cells: 3205.8;Suprabasal keratinocytes: 3612.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 798.6;HaCaT: 1072.9;HBEC3-KT: 1527.6;hTCEpi: 2232.0;OE19: 1675.1;SK-BR-3: 1579.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" 2.2 0.8 1.5 24.9 1.6 0.2 78.3 1.5 2.0 530.8 1.3 241.0 265.4 5.4 14.7 3719.5 20.4 18.5 4.2 1.5 1.5 70.1 16.3 82.7 0.6 1.5 1.5 1.4 17.7 125.2 5.1 1.1 1.5 19.6 240.0 0.0 550.3 39.0 2.2 608.0 209.0 13.1 1.4 1.3 119.2 0.7 1.7 149.0 98.6 0.0 449.7 32.9 1174.2 1.5 798.6 0.2 0.1 0.2 0.2 0.3 7.4 0.2 0.1 0.2 0.1 97.6 140.1 0.6 2.3 0.2 0.5 1072.9 0.0 1527.6 0.1 0.5 0.3 0.1 10.8 7.3 0.0 0.0 0.9 0.6 2232.0 0.5 20.7 0.3 0.3 0.1 0.6 1.1 0.2 140.0 0.7 1.1 0.4 1675.1 1.9 0.6 0.6 2.8 8.1 51.2 0.7 0.7 2.2 1579.1 2.1 36.5 3.9 1.7 0.0 0.7 0.8 1.1 2.0 0.4 0.8 0.9 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.6 1.5 2.0 1.5 1.5 1.5 1.5 1.5 1.4 1.7 1.5 2.7 60.9 162.6 2.3 4.2 2340.8 448.6 770.5 657.9 0.0 256.2 178.3 5.3 270.2 387.7 35.0 0.0 2.7 2.2 1058.2 49.0 197.5 0.0 37.3 6.4 21.5 153.4 0.0 0.0 65.8 1.5 22.8 85.6 80.3 28.0 0.2 1.1 9.5 0.3 0.0 0.0 660.1 126.1 0.3 213.7 0.0 0.0 3.0 241.9 0.0 2.0 0.0 0.0 0.0 0.1 343.0 1098.9 0.0 7.5 619.3 1549.1 4.9 56.2 0.0 0.0 1.3 27.1 0.0 0.0 3205.8 3612.0 0.3 8.7 13.6 580.9 824.9 SAMHD1 "AGS5, HDDC1, Mg11, MOP-5, SBBI88" ENSG00000101347 "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1" Q9Y3Z3 20 36890229-36951843 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, DNA replication, Host-virus interaction, Immunity, Innate immunity" "Allosteric enzyme, Hydrolase" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 214.2;Endometrial ciliated cells: 173.8;Kupffer cells: 280.2;Macrophages: 326.4;monocytes: 257.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 510.8;BJ hTERT+ SV40 Large T+: 165.8;BJ hTERT+ SV40 Large T+ RasG12V: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047072 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 91000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane" "HPA047072: AB_2679921" "unprognostic (1.09e-1)" "unprognostic (7.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (4.07e-2)" "unprognostic (2.03e-1)" "unprognostic (3.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.44e-1)" "unprognostic (9.06e-2)" "unprognostic (3.18e-2)" "unprognostic (2.72e-2)" 79.5 39.9 11.9 94.3 12.4 11.5 65.7 11.6 12.2 39.1 33.2 58.4 29.4 33.0 9.1 45.8 81.8 40.2 60.5 11.4 16.6 12.2 26.1 68.0 78.0 16.8 15.0 38.0 42.2 14.0 21.7 36.0 17.9 26.3 28.8 5.5 32.6 18.1 23.8 27.8 55.2 44.1 17.6 94.2 45.0 12.6 18.0 29.3 31.7 20.7 51.2 55.3 39.9 26.4 29.9 10.9 3.7 15.6 510.8 101.8 5.5 10.8 37.7 165.8 187.8 39.1 11.2 64.4 19.9 14.4 94.9 21.2 34.7 27.8 30.9 17.4 20.6 5.3 18.8 30.9 39.3 28.2 5.1 96.4 1.0 45.3 1.9 13.3 26.4 0.0 13.7 18.8 5.4 12.0 0.0 19.2 7.9 18.3 25.9 2.8 21.7 35.3 15.7 8.2 23.0 4.2 20.2 10.2 28.2 4.7 20.5 125.4 13.9 11.5 13.5 25.1 28.5 7.3 20.3 21.7 14.5 3.2 7.1 1.4 147.7 4.8 52.2 174.4 47.0 4.5 55.7 53.3 278.6 3.1 55.5 47.6 18.5 56.2 167.0 96.4 95.8 144.3 11.9 12.4 11.6 12.2 11.4 16.6 16.8 15.0 17.9 17.6 18.0 26.4 48.7 28.9 25.5 4.2 19.4 6.4 2.3 7.8 5.7 5.5 6.9 5.8 17.3 14.3 35.3 1.8 4.2 2.6 214.2 2.6 0.0 10.3 3.3 173.8 12.7 44.3 6.0 30.7 8.6 10.2 3.3 71.4 13.3 40.6 12.6 10.5 42.5 20.1 137.2 6.7 8.5 5.7 8.2 280.2 52.3 4.8 82.3 326.4 5.4 36.5 257.9 25.1 116.4 14.1 3.5 7.5 31.3 96.3 54.8 1.9 1.1 1.9 104.4 2.9 59.2 9.6 31.9 10.2 4.9 12.1 5.8 2.9 102.6 9.7 5.5 4.9 SAP130 FLJ12761 ENSG00000136715 "Sin3A associated protein 130" Q9H0E3 2 127941217-128028120 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.3" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Late spermatids: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034664 Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA034664: AB_10603238" "unprognostic (2.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.33e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (2.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.43e-1)" "unprognostic (3.92e-2)" "unprognostic (6.77e-2)" "unprognostic (3.75e-2)" "unprognostic (5.26e-2)" "unprognostic (4.41e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" 9.1 8.6 8.8 8.7 8.5 21.7 8.2 8.5 10.2 10.5 5.1 10.3 8.3 10.4 9.2 10.4 9.6 7.2 8.5 8.1 10.8 7.2 8.3 8.0 10.0 6.4 7.9 11.2 8.7 12.4 14.5 9.0 7.1 8.7 9.7 8.6 9.1 7.9 11.9 12.9 9.8 10.2 6.1 8.5 9.7 47.3 8.0 14.8 8.8 13.0 12.6 9.5 10.3 8.8 35.3 18.9 35.3 28.6 22.9 15.7 38.5 22.0 21.4 33.4 26.2 45.1 14.4 29.4 19.3 25.0 17.4 24.0 39.3 22.7 34.5 16.3 25.2 29.2 16.7 35.9 27.5 25.5 22.2 14.8 16.7 44.1 27.5 17.6 27.0 24.4 35.9 21.1 28.2 39.3 35.6 20.0 36.6 20.7 21.1 24.3 29.0 19.6 17.9 30.7 18.5 22.3 23.2 21.7 13.6 22.1 16.4 17.3 23.2 32.1 34.5 30.1 23.6 29.3 31.2 34.3 26.4 17.0 21.0 2.3 4.2 4.6 5.3 2.7 4.0 2.0 3.8 3.5 3.4 5.0 2.7 3.1 14.0 3.6 8.6 6.2 2.7 3.8 8.8 8.5 8.5 10.2 8.1 10.8 6.4 7.9 7.1 6.1 8.0 8.8 5.4 0.0 10.9 29.0 7.9 7.9 2.3 3.2 5.7 5.2 6.5 5.3 15.2 2.8 3.1 1.8 8.4 11.9 9.4 13.1 0.0 4.9 71.5 4.6 8.6 6.2 6.7 11.6 25.4 4.7 12.8 5.2 8.6 8.7 1.3 5.3 5.3 5.8 7.8 8.4 28.9 7.0 4.1 8.4 6.3 44.2 8.4 7.0 5.4 16.9 4.9 5.0 6.2 26.2 31.0 6.1 7.8 8.2 13.2 4.9 6.5 3.4 4.0 5.8 6.6 4.4 5.5 31.0 17.9 9.2 10.4 19.3 7.6 3.7 7.8 4.3 SAPCD1 "C6orf26, NG23" ENSG00000228727 "Suppressor APC domain containing 1" Q5SSQ6 6 31762996-31764851 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.3" "Cell type enriched" "Detected in single" 15 "Respiratory ciliated cells: 1.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.4;U-2 OS: 1.1;U-937: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071699 Approved "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Cell Junctions" "HPA071699: AB_2686433" "unprognostic (9.25e-4)" "unprognostic (1.32e-1)" "unprognostic (3.41e-2)" "unprognostic (3.28e-1)" "unprognostic (9.34e-2)" "unprognostic (8.02e-4)" "unprognostic (1.63e-2)" "unprognostic (3.80e-2)" "unprognostic (2.01e-1)" "unprognostic (8.16e-3)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "unprognostic (8.15e-10)" "unprognostic (2.65e-2)" "unprognostic (4.45e-1)" "unprognostic (3.57e-1)" "unprognostic (7.98e-5)" 2.7 1.1 0.4 0.0 0.4 0.2 2.5 0.5 0.9 2.4 0.4 3.7 0.0 2.5 0.1 2.5 3.9 0.0 1.2 0.4 0.3 7.4 3.1 2.0 0.6 0.4 0.5 3.8 2.1 0.0 6.1 0.1 0.4 6.0 0.2 1.2 2.3 0.1 1.0 28.3 3.9 0.1 0.4 4.8 2.6 3.6 0.4 0.2 2.2 0.0 0.1 2.5 2.2 0.4 0.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.0 0.5 0.0 0.3 0.2 0.0 0.1 0.5 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.7 0.4 0.2 0.2 0.2 0.5 0.0 0.1 0.7 1.4 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.2 0.2 0.1 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.7 0.1 0.4 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.4 0.3 0.4 0.5 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCARA5 "FLJ23907, MGC45780, NET33" ENSG00000168079 "Scavenger receptor class A member 5" Q6ZMJ2 8 27869883-27992673 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 90.0" "Group enriched" "Detected in some" 4 "Fibroblasts: 174.0;Leydig cells: 135.8;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 121 "plasmacytoid DC: 21.1" "Lineage enriched" "Detected in single" 211 "dendritic cells: 21.1" "Cell line enriched" "Detected in some" 20 "ASC diff: 229.1" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 5 "spinal cord: 19.5" HPA024661 Approved NA NA 1400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA024661: AB_1853902" "unprognostic (2.76e-2)" "unprognostic (7.20e-3)" "unprognostic (1.44e-2)" "unprognostic (3.53e-2)" "unprognostic (2.34e-2)" "unprognostic (4.62e-2)" "unprognostic (2.01e-1)" "unprognostic (2.15e-1)" "unprognostic (9.13e-2)" "unprognostic (2.40e-1)" "unprognostic (4.21e-2)" "unprognostic (1.10e-1)" "unprognostic (7.09e-6)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" 60.5 4.0 0.4 7.2 0.8 0.0 34.6 0.8 1.8 16.6 4.9 38.5 8.7 2.9 8.2 21.1 23.7 22.5 90.0 0.6 0.4 1.0 4.1 20.2 2.4 0.3 0.2 11.2 2.4 0.2 5.4 12.5 0.2 8.4 33.7 0.3 29.0 3.3 15.1 31.1 26.3 6.5 0.5 3.3 27.3 11.6 0.2 3.2 21.1 34.5 2.1 77.1 36.8 0.3 0.0 7.9 0.0 0.0 229.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 11.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.1 0.4 0.8 0.8 1.8 0.6 0.4 0.3 0.2 0.2 0.5 0.2 0.3 7.1 0.0 0.0 0.0 0.1 6.5 0.1 0.0 0.6 0.0 0.5 0.6 4.6 0.0 0.0 0.0 0.0 0.1 6.7 0.2 0.0 0.0 1.5 0.7 27.9 2.4 0.0 0.0 0.3 0.0 0.4 174.0 4.1 0.8 0.0 0.0 0.0 0.0 0.4 0.0 2.9 0.0 0.0 0.0 17.0 4.6 135.8 1.3 7.2 5.6 0.0 1.9 0.0 0.0 0.2 0.0 0.0 11.3 0.8 0.1 0.0 0.0 0.0 0.1 0.0 7.4 3.6 0.7 1.1 0.9 6.0 0.1 1.1 44.5 0.3 0.1 SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6" "Cell type enhanced" "Detected in many" "Adipocytes: 65.9;Endothelial cells: 51.3;Hepatic stellate cells: 62.4;Langerhans cells: 37.7;Microglial cells: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 12.1;REH: 11.5;TIME: 37.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 2000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" 15.2 5.0 1.5 3.1 1.8 0.4 12.7 1.4 3.4 5.6 1.4 5.2 0.0 6.0 0.9 2.7 6.5 2.2 11.8 1.6 1.8 7.5 7.5 16.3 2.1 2.7 1.7 2.6 3.1 0.1 3.8 4.3 2.2 4.6 1.2 0.2 4.2 0.0 5.3 3.1 5.4 1.2 1.7 25.6 4.2 1.6 1.7 0.5 18.8 1.9 1.0 5.6 4.6 2.8 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.3 12.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 11.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 37.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 1.8 1.4 3.4 1.6 1.8 2.7 1.7 2.2 1.7 1.7 2.8 65.9 22.4 17.6 6.5 0.6 3.4 0.4 0.7 1.2 1.2 0.8 0.9 3.5 0.0 2.9 3.7 4.2 0.4 2.0 4.9 1.9 0.4 0.3 0.5 0.9 51.3 0.0 3.4 5.4 0.2 0.2 2.5 4.1 1.1 3.8 0.3 62.4 2.3 9.0 0.0 3.5 4.4 0.0 15.7 37.7 0.4 1.2 10.1 3.6 26.2 4.8 0.7 0.0 0.5 1.1 0.3 1.2 1.2 0.0 0.7 3.0 0.2 3.0 2.0 0.0 2.1 3.0 0.5 0.6 0.3 2.7 1.2 1.0 1.3 2.2 0.8 SCCPDH "CGI-49, NET11" ENSG00000143653 "Saccharopine dehydrogenase (putative)" Q8NBX0 1 246724409-246768137 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 159.5" "Group enriched" "Detected in all" 4 "Early spermatids: 1380.7;Spermatocytes: 822.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 20 "basophil: 872.9" "Lineage enriched" "Detected in all" 26 "granulocytes: 872.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050775, HPA076030" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA050775: AB_2681231, HPA076030: " "unprognostic (4.25e-1)" "unprognostic (3.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (2.83e-2)" "unprognostic (6.43e-2)" "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (5.51e-2)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (2.70e-2)" "unprognostic (9.63e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.93e-2)" 26.6 53.7 35.1 14.4 45.5 35.7 23.6 51.5 43.2 22.6 40.8 27.2 34.4 26.2 17.6 9.3 31.6 21.6 32.8 35.3 45.4 49.8 158.2 21.0 13.5 64.0 45.2 22.4 18.8 36.5 24.3 23.8 64.3 39.4 26.8 31.7 15.3 26.0 60.7 24.1 34.6 24.0 57.0 11.5 28.0 159.5 47.3 20.1 33.5 54.7 10.6 81.5 12.0 86.8 55.3 53.2 37.7 22.8 44.5 55.7 0.5 42.3 58.8 70.1 58.3 32.7 150.6 29.3 53.8 49.0 38.9 17.7 32.4 12.6 71.6 40.8 11.9 49.6 46.9 65.9 41.6 97.1 40.7 37.6 5.9 47.4 4.8 65.7 76.4 60.0 62.9 0.1 70.9 13.5 101.6 122.6 56.5 29.6 41.7 83.8 48.5 0.3 216.6 128.2 42.7 48.0 57.3 2.5 39.0 20.2 42.1 99.6 49.8 32.1 28.5 78.7 110.5 138.0 51.1 17.4 54.7 130.2 43.3 872.9 24.3 44.1 18.1 22.2 22.4 11.2 5.4 15.7 10.7 9.4 7.1 22.0 6.4 34.1 15.4 18.2 4.0 17.1 35.1 45.5 51.5 43.2 35.3 45.4 64.0 45.2 64.3 57.0 47.3 86.8 25.0 6.4 11.5 25.8 8.0 30.1 40.6 54.6 1.8 31.2 42.4 17.5 38.0 55.8 40.5 152.6 18.8 41.4 14.6 42.4 31.3 67.2 1380.7 72.7 39.4 23.6 44.9 54.7 23.7 69.0 17.4 35.7 32.6 111.9 57.2 49.2 22.5 187.8 89.4 6.7 20.5 27.4 52.9 45.7 13.7 245.6 47.5 29.7 48.0 10.3 20.3 67.4 18.6 27.2 37.3 75.2 27.8 47.4 8.3 49.2 138.4 69.7 79.4 39.2 19.7 36.7 39.4 822.3 76.2 5.6 68.5 84.6 17.0 42.8 55.0 201.9 SCGB3A1 "HIN-1, HIN1, LU105, PnSP-2, UGRP2" ENSG00000161055 "Secretoglobin family 3A member 1" Q96QR1 5 180590105-180591499 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 270.0;lung: 508.1;salivary gland: 746.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2883.9;Breast myoepithelial cells: 4199.8;Club cells: 13674.8;Respiratory ciliated cells: 3325.6;Urothelial cells: 3139.7" "Group enriched" "Detected in many" 7 "endometrial cancer: 114.2;lung cancer: 288.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 51.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "NB-4: 2.3;T-47d: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 10000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (7.70e-3)" "unprognostic (4.90e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.36e-2)" "unprognostic (7.87e-3)" "unprognostic (2.00e-2)" "unprognostic (3.20e-1)" "unprognostic (4.88e-2)" "unprognostic (3.55e-2)" "unprognostic (7.19e-2)" "unprognostic (8.74e-3)" "unprognostic (5.43e-2)" "unprognostic (4.62e-1)" "unprognostic (4.50e-1)" "unprognostic (1.50e-2)" 1.8 1.5 1.1 0.2 1.2 0.5 122.4 0.7 1.2 270.0 11.7 0.5 0.6 1.5 1.2 74.8 29.9 2.9 0.7 1.1 5.9 1.5 7.0 508.1 0.4 1.4 1.6 2.0 18.2 0.0 12.6 0.1 1.0 37.9 0.0 0.0 746.5 2.4 0.3 4.9 1.0 0.0 1.2 9.4 50.7 3.0 3.0 0.8 3.1 0.0 0.8 14.5 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 20.3 2.4 17.2 13.3 1.8 3.3 4.5 10.1 0.0 5.9 5.0 0.0 0.0 51.8 0.2 4.3 2.6 1.1 1.2 0.7 1.2 1.1 5.9 1.4 1.6 1.0 1.2 3.0 1.5 36.4 173.1 1441.5 0.0 5.9 0.5 51.2 2883.9 0.6 0.0 1831.7 4199.8 0.4 1554.2 13674.8 0.0 0.0 0.0 30.4 0.1 0.0 20.5 0.1 1.6 0.1 40.5 0.0 10.7 0.2 1.6 0.3 15.2 3.6 1.7 35.3 1.0 68.9 1.1 0.4 0.0 0.0 0.1 1566.5 1.2 0.6 0.2 0.6 14.8 5.4 0.0 0.6 0.0 0.0 0.0 0.1 146.1 0.5 0.0 0.0 214.9 0.0 0.0 3325.6 0.0 0.0 1.6 305.2 0.3 4.4 140.8 0.4 0.0 20.2 0.1 0.2 3139.7 SCMH1 Scml3 ENSG00000010803 "Scm polycomb group protein homolog 1" Q96GD3 1 41027200-41242154 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 125.4;Excitatory neurons: 161.3;Inhibitory neurons: 213.0;Microglial cells: 102.1;Oligodendrocyte precursor cells: 154.3;Oligodendrocytes: 77.9;Spermatocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048898, HPA053292" Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA048898: , HPA053292: AB_2797246" "unprognostic (6.02e-2)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (1.98e-2)" "unprognostic (8.77e-2)" "unprognostic (8.93e-3)" "unprognostic (2.77e-2)" "unprognostic (1.40e-1)" "unprognostic (7.38e-2)" "unprognostic (9.47e-2)" "unprognostic (1.63e-1)" "unprognostic (8.08e-2)" "prognostic favorable (5.80e-4)" 22.0 24.0 15.2 11.3 15.9 17.8 23.2 16.5 18.1 32.0 18.6 54.6 12.7 35.4 20.5 14.0 33.1 15.8 39.3 16.1 16.9 29.8 19.7 20.6 10.4 13.6 14.7 36.3 40.1 34.7 27.6 11.0 13.1 40.4 17.0 21.0 27.5 30.7 44.9 13.3 23.4 24.6 12.2 15.5 32.5 32.8 16.7 16.6 24.1 34.2 10.5 38.9 21.3 14.1 19.5 12.8 29.9 27.5 13.4 25.4 0.1 15.4 26.7 25.2 26.0 12.3 24.6 35.4 11.4 28.1 21.1 4.8 23.3 20.6 21.6 24.7 17.8 16.6 17.7 31.2 58.2 35.7 26.2 27.7 20.5 16.7 40.2 30.5 25.7 43.3 15.7 26.8 25.0 10.6 36.0 30.8 27.7 16.4 13.5 39.3 31.3 21.0 20.4 24.1 21.0 22.5 26.7 21.1 22.1 20.2 18.8 90.7 19.0 26.3 20.4 16.4 28.5 27.1 16.2 38.6 16.5 31.5 24.4 0.6 0.6 1.2 1.6 1.1 2.0 2.4 1.9 1.5 1.9 1.1 1.3 1.1 0.0 1.6 0.2 3.9 1.4 0.9 15.2 15.9 16.5 18.1 16.1 16.9 13.6 14.7 13.1 12.2 16.7 14.1 7.1 9.6 10.8 125.4 9.4 6.6 25.8 11.5 26.7 17.0 16.4 17.0 14.9 18.6 7.4 12.9 16.7 7.3 10.8 7.2 1.9 11.4 9.4 7.2 13.8 9.6 8.4 16.0 161.3 21.3 3.3 11.4 15.3 13.1 5.1 11.9 8.9 7.3 6.2 8.4 213.0 7.4 8.2 3.3 6.5 12.4 16.4 3.2 8.8 102.1 2.7 6.9 2.1 154.3 77.9 12.4 6.2 18.0 20.2 23.3 10.4 18.1 5.8 14.2 19.7 11.9 10.3 54.3 26.1 6.1 3.7 4.8 7.4 3.5 12.4 14.5 SDK1 FLJ31425 ENSG00000146555 "Sidekick cell adhesion molecule 1" Q7Z5N4 7 3301252-4269000 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 12.6" "Cell type enhanced" "Detected in many" "Early spermatids: 96.1;Excitatory neurons: 222.4;Inhibitory neurons: 551.0;Late spermatids: 190.0;Microglial cells: 201.4;Oligodendrocyte precursor cells: 112.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;BEWO: 10.5;RPTEC TERT1: 8.7;RT4: 11.2;SuSa: 10.3;U-2 OS: 13.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011392 Approved Approved Cytosol NA NA 9500000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA011392: AB_1856648" "unprognostic (2.39e-1)" "unprognostic (1.80e-2)" "unprognostic (1.44e-1)" "unprognostic (5.83e-2)" "unprognostic (2.15e-3)" "unprognostic (3.02e-2)" "unprognostic (1.23e-1)" "unprognostic (9.93e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-1)" "prognostic favorable (4.08e-4)" "unprognostic (2.16e-1)" "unprognostic (2.49e-2)" "unprognostic (7.84e-2)" "unprognostic (1.59e-1)" "unprognostic (8.44e-2)" "unprognostic (1.37e-1)" 3.6 0.4 0.4 4.0 1.0 0.8 2.1 0.0 1.6 9.4 4.8 4.0 1.0 3.2 2.6 1.6 2.6 1.4 1.1 3.4 1.0 1.7 0.1 4.0 1.5 1.6 2.1 2.2 12.6 0.8 2.2 1.7 2.5 1.6 1.3 1.5 0.8 4.1 0.9 1.4 2.4 2.7 0.8 5.3 2.0 3.5 1.6 2.5 0.5 1.6 1.9 5.2 2.2 0.5 2.2 1.8 8.5 0.0 0.0 0.0 10.5 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.4 0.0 3.4 0.2 0.9 0.0 0.2 0.0 5.0 0.0 0.4 0.3 4.1 0.0 0.0 1.7 0.0 0.4 0.5 0.0 0.7 0.1 0.0 0.0 4.2 2.2 0.0 0.0 2.9 0.1 0.0 6.3 5.9 0.0 8.7 11.2 5.3 7.7 0.0 0.0 0.0 10.3 0.0 2.8 0.2 0.0 13.2 0.0 3.8 0.0 0.0 0.0 0.0 1.8 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 1.6 3.4 1.0 1.6 2.1 2.5 0.8 1.6 0.5 1.2 0.0 3.0 31.3 0.1 1.3 0.5 2.3 0.6 22.3 0.6 1.8 20.2 1.5 5.5 5.5 0.0 3.6 1.3 0.0 0.0 1.5 96.1 16.9 57.1 1.9 4.9 0.0 222.4 5.4 0.7 11.6 0.5 9.9 0.0 23.4 1.1 0.0 0.5 1.7 551.0 0.5 0.0 0.3 2.1 190.0 1.8 0.7 5.4 201.4 0.0 0.2 0.0 112.1 14.3 2.2 0.0 5.7 0.0 0.7 0.0 1.5 6.7 1.2 6.6 1.7 7.8 9.8 5.5 0.3 0.4 1.9 0.7 1.4 0.1 0.4 SEC14L1 "PRELID4A, SEC14L" ENSG00000129657 "SEC14 like lipid binding 1" Q92503 17 77088749-77217101 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 430.3;Hepatic stellate cells: 286.3;Late spermatids: 740.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 355.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 355.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 398.1;TIME: 251.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021463, HPA028703" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021463: AB_2670712, HPA028703: AB_10602300" "unprognostic (1.19e-1)" "unprognostic (8.61e-2)" "unprognostic (1.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (7.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-3)" "unprognostic (3.09e-1)" "unprognostic (4.30e-2)" 66.7 54.2 42.6 44.6 63.3 65.5 57.6 75.4 60.7 39.5 36.3 19.5 21.8 24.6 28.2 31.5 27.3 34.3 50.2 49.5 57.5 42.0 25.3 66.9 49.7 64.0 63.0 20.7 30.8 25.1 27.9 76.7 54.6 18.3 19.8 19.0 35.0 16.8 94.1 20.5 21.7 27.1 46.2 49.9 31.7 51.9 63.6 24.1 41.6 54.7 46.2 26.0 20.6 50.9 55.0 45.4 65.6 105.0 27.4 36.3 24.1 47.4 42.0 57.8 49.5 55.7 39.6 143.1 93.3 65.0 71.1 26.3 36.0 47.8 72.6 27.3 50.1 81.1 42.4 75.9 44.4 26.8 39.8 46.6 20.7 47.8 47.8 69.1 398.1 24.3 55.8 136.0 79.2 36.2 28.5 22.4 25.0 25.7 43.7 20.3 104.2 112.2 91.2 26.2 59.5 44.8 51.1 31.3 32.1 58.3 27.9 20.7 251.1 65.4 60.6 35.0 37.7 71.1 64.8 79.9 27.9 22.1 21.6 33.8 19.4 48.9 7.1 28.3 8.9 14.6 6.9 5.3 12.7 10.8 10.9 5.9 355.0 10.0 33.3 18.9 12.5 11.5 42.6 63.3 75.4 60.7 49.5 57.5 64.0 63.0 54.6 46.2 63.6 50.9 430.3 41.7 18.6 55.8 69.4 29.3 23.5 22.5 37.0 31.5 86.5 37.8 17.6 15.7 28.9 27.6 18.8 10.8 77.5 20.3 99.7 18.0 242.6 114.8 46.7 205.9 19.7 86.5 33.0 20.7 10.8 34.0 35.2 240.5 34.7 104.3 286.3 11.1 51.6 37.0 54.6 14.0 61.1 127.2 48.1 740.3 26.4 115.1 35.6 62.8 76.1 31.4 34.0 23.1 44.4 41.8 15.2 17.3 269.1 39.5 9.6 24.8 69.5 17.2 39.5 36.4 36.3 45.1 42.5 25.1 30.4 13.3 51.6 64.3 11.5 39.1 SEC14L2 "C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1" ENSG00000100003 "SEC14 like lipid binding 2" O76054 22 30396941-30425303 "Predicted intracellular proteins" "Transcription, Transcription regulation, Transport" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 86.0;liver: 243.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 146.3;Muller glia cells: 112.6;Pancreatic endocrine cells: 115.2;Proximal enterocytes: 52.8;Rod photoreceptor cells: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.7;naive CD8 T-cell: 2.7" "Lineage enriched" "Detected in single" 7 "T-cells: 3.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 93.9;hTCEpi: 47.3;hTERT-RPE1: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064466 Approved Supported Nucleoplasm,Cytosol NA NA 580000 "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "HPA064466: AB_2685270" "prognostic favorable (3.05e-4)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (5.59e-3)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.63e-6)" "unprognostic (1.25e-3)" "unprognostic (3.76e-3)" "unprognostic (2.23e-1)" "unprognostic (2.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.63e-3)" "unprognostic (1.17e-3)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-3)" "unprognostic (2.01e-1)" 2.8 1.4 33.1 2.6 43.3 4.1 44.4 35.8 37.1 6.0 35.4 3.4 21.6 3.4 86.0 20.6 3.1 7.4 2.4 34.3 39.7 8.0 243.8 2.7 3.1 45.4 39.5 2.6 2.6 11.0 11.1 1.5 33.2 52.3 1.3 64.2 9.3 13.7 0.7 7.0 24.3 3.4 30.4 1.1 5.9 1.3 41.4 4.2 9.0 0.5 4.5 3.2 7.7 32.2 24.8 5.5 5.0 6.4 6.5 16.8 0.4 18.0 15.5 12.0 13.1 1.6 15.9 0.5 5.6 22.7 20.5 20.0 3.0 93.9 13.8 2.2 4.1 0.4 5.4 8.0 9.2 0.0 7.1 11.5 47.3 11.5 20.8 55.5 29.7 4.2 0.1 0.5 22.2 4.0 3.0 0.5 0.1 13.9 7.6 1.2 8.0 0.6 20.7 7.8 2.8 3.1 13.3 3.2 11.2 0.6 14.7 0.5 41.2 15.8 10.4 6.8 12.7 0.3 0.2 0.8 32.4 0.1 12.6 0.0 0.1 0.2 0.5 0.1 0.2 0.4 1.4 0.3 0.0 0.3 3.7 2.7 0.3 0.0 0.0 0.5 0.7 0.8 33.1 43.3 35.8 37.1 34.3 39.7 45.4 39.5 33.2 30.4 41.4 32.2 1.1 3.2 5.8 33.6 1.1 4.1 18.0 25.2 6.8 9.2 36.5 21.7 1.2 12.8 10.3 0.0 16.7 4.2 3.2 0.6 5.9 22.9 8.3 2.9 2.3 2.4 1.2 17.2 9.8 18.7 0.3 5.1 5.6 5.8 5.7 0.7 7.1 146.3 0.5 13.5 6.7 2.0 4.1 4.4 0.4 10.7 1.2 2.6 7.2 1.9 0.2 112.6 0.0 21.6 13.2 115.2 0.0 0.7 2.5 15.3 52.8 8.7 3.9 56.0 0.0 2.8 4.0 0.6 1.2 5.6 2.0 3.0 7.4 0.1 2.1 7.8 SELP "CD62, CD62P, GMP140, GRMP, PADGEM, PSEL" ENSG00000174175 "Selectin P" P16109 1 169588849-169630193 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 14.7;Endothelial cells: 51.8;Hepatic stellate cells: 33.9;Macrophages: 10.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 8.3;T-reg: 8.8" "Group enriched" "Detected in many" 7 "granulocytes: 8.3;T-cells: 8.8" "Group enriched" "Detected in some" 38 "EFO-21: 36.0;HEL: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002145, HPA002655, HPA005990" Enhanced NA NA 520000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002145: AB_563984, HPA002655: AB_1078480, HPA005990: AB_1078479" "unprognostic (3.37e-2)" "unprognostic (2.98e-4)" "unprognostic (4.11e-1)" "unprognostic (1.46e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.12e-4)" "unprognostic (5.30e-4)" "unprognostic (4.14e-2)" "unprognostic (3.59e-1)" "unprognostic (1.74e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.19e-1)" "unprognostic (8.24e-3)" "unprognostic (1.74e-2)" "unprognostic (7.85e-3)" "unprognostic (1.66e-1)" 11.3 2.3 0.2 11.9 0.6 2.2 10.6 0.0 0.6 8.9 3.7 3.3 5.1 6.4 4.1 5.1 6.7 9.5 6.7 0.3 0.0 5.6 2.5 12.6 7.0 0.2 0.2 1.8 1.2 3.1 2.2 6.3 0.2 6.1 4.1 0.0 2.7 5.7 1.0 3.6 4.8 14.2 0.1 1.0 2.8 0.7 0.7 2.6 4.0 1.8 12.6 14.4 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.4 0.6 0.0 0.2 0.0 1.1 0.5 0.2 0.0 0.1 0.2 0.1 2.1 0.3 0.0 0.1 8.8 7.8 0.2 0.6 0.0 0.6 0.3 0.0 0.2 0.2 0.2 0.1 0.7 0.2 14.7 0.0 3.6 0.3 0.4 3.7 0.1 0.0 0.6 0.0 0.2 0.1 1.9 1.5 0.0 1.8 0.0 2.6 0.1 0.0 0.0 0.0 2.0 0.1 0.1 51.8 0.0 5.2 0.5 0.2 0.0 1.5 0.0 0.0 0.0 0.0 33.9 0.4 0.2 0.0 0.2 0.0 0.0 1.5 3.6 0.1 0.3 10.1 3.6 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.1 3.4 4.1 0.5 0.0 0.0 0.3 SEPTIN4 "ARTS, C17orf47, CE5B3, FLJ40121, H5, hCDCREL-2, hucep-7, MART, PNUTL2, SEPT4" ENSG00000108387 "Septin 4" "O43236, Q8NEP4" 17 58520250-58544368 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 1288.2;choroid plexus: 593.0;retina: 404.5" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 52.0;Smooth muscle cells: 38.9" "Cancer enhanced" "Detected in all" "glioma: 8.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 14.0;hTERT-RPE1: 19.4;SK-MEL-30: 32.8" "CAB006855, HPA021587, HPA022905, HPA028424" Enhanced Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "CAB006855: , HPA021587: AB_1856686, HPA022905: AB_1856687, HPA028424: AB_10601690" "unprognostic (1.12e-1)" "unprognostic (5.54e-2)" "unprognostic (8.36e-3)" "unprognostic (8.01e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-2)" "unprognostic (6.88e-3)" "unprognostic (2.73e-2)" "unprognostic (2.76e-1)" "unprognostic (8.02e-2)" "unprognostic (1.97e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (6.40e-3)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (8.75e-3)" 46.6 165.0 832.1 5.0 1011.1 0.5 33.5 861.9 1288.2 13.9 593.0 15.3 4.9 12.4 6.9 5.9 14.2 17.1 56.3 774.4 799.2 31.8 56.6 39.6 14.4 864.7 904.6 15.8 8.7 9.4 23.1 20.9 859.8 8.6 5.3 404.5 9.2 6.5 10.8 11.1 12.1 11.7 798.0 49.5 11.5 25.7 925.2 4.4 23.2 13.7 7.3 12.2 12.1 1080.0 0.0 0.6 1.2 3.6 1.4 0.2 0.6 0.2 0.5 2.1 2.4 0.2 0.5 0.0 5.1 0.8 3.2 0.4 1.8 1.4 0.5 0.3 0.9 1.3 0.3 7.6 14.0 0.1 0.7 7.2 2.9 0.5 2.6 19.4 0.6 1.9 0.0 3.8 0.2 0.5 0.0 0.1 0.6 0.0 0.9 0.2 0.0 1.6 0.0 0.1 3.9 2.1 0.1 0.2 32.8 1.6 0.8 0.4 0.0 0.3 1.6 0.0 1.4 1.0 0.6 0.0 1.1 0.0 0.4 0.0 3.6 0.8 4.9 0.5 1.5 1.6 1.0 1.3 3.7 0.3 1.8 1.4 1.9 1.0 0.0 0.2 0.7 3.6 832.1 1011.1 861.9 1288.2 774.4 799.2 864.7 904.6 859.8 798.0 925.2 1080.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 SERPINB10 "bomapin, PI10" ENSG00000242550 "Serpin family B member 10" P48595 18 63897174-63936111 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 60 "bone marrow: 74.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.4;Club cells: 2.7;Erythroid cells: 1.3;Kupffer cells: 1.2;monocytes: 4.7;Respiratory ciliated cells: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;eosinophil: 1.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "U-937: 104.1" "Not detected" "Not detected" "HPA015480, HPA059582" Uncertain Supported Nucleoplasm,Cytosol NA NA 59000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA015480: AB_1855456, HPA059582: AB_2684072" "unprognostic (4.66e-1)" "unprognostic (5.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (9.56e-2)" "unprognostic (2.56e-1)" "unprognostic (4.59e-1)" "unprognostic (1.10e-1)" "unprognostic (3.64e-1)" "unprognostic (1.25e-4)" 0.3 0.1 0.1 0.1 0.2 74.7 0.0 0.5 0.4 0.3 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.1 1.2 0.1 0.1 0.1 0.7 0.1 0.0 0.3 0.9 0.0 0.0 0.6 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.1 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.0 14.5 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.7 0.1 1.5 0.1 0.0 0.0 0.1 0.1 104.1 0.1 0.1 1.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.3 0.1 0.2 0.5 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 4.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.2 SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.6;skin 1: 239.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 964.1;Basal prostatic cells: 358.7;Basal respiratory cells: 272.9;Squamous epithelial cells: 535.4;Suprabasal keratinocytes: 1215.3;Urothelial cells: 564.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1279.3;HBEC3-KT: 425.6;hTCEpi: 875.0;hTERT-HME1: 217.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 770000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" 0.6 0.0 0.0 4.3 0.0 0.2 37.1 0.1 0.1 38.5 0.1 4.8 16.7 0.1 0.1 216.6 1.4 2.7 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 9.9 4.5 0.0 37.6 1.7 1.4 239.7 22.1 0.2 0.0 0.0 9.7 2.8 0.0 13.9 0.1 0.0 39.9 90.9 78.7 0.1 80.8 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 73.4 0.1 3.8 0.0 0.1 1279.3 0.0 425.6 0.0 0.0 0.0 0.0 95.8 0.2 0.0 0.0 0.6 0.1 875.0 0.0 217.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 179.9 93.4 0.1 0.0 0.2 0.0 95.1 1.4 0.0 60.2 0.3 0.0 0.3 0.2 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.2 0.9 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 964.1 358.7 272.9 224.3 0.0 5.1 27.3 0.2 0.0 90.0 3.7 0.0 0.3 0.1 14.2 0.0 0.1 9.0 6.2 0.1 5.4 3.5 0.0 0.3 0.0 0.2 5.8 12.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.3 34.6 0.0 57.6 18.6 0.6 1.8 62.2 0.0 0.0 0.0 0.0 0.0 0.1 16.3 51.7 0.0 2.5 85.4 13.5 0.1 85.4 0.0 0.0 0.0 7.1 6.6 2.2 535.4 1215.3 0.1 4.0 0.1 30.6 564.9 SERPINB8 "CAP2, PI8" ENSG00000166401 "Serpin family B member 8" P50452 18 63970029-64019779 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 58.8" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 120.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB034300 Enhanced Approved Nucleoplasm,Cytosol NA NA 920000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB034300: AB_2186486" "unprognostic (8.49e-2)" "unprognostic (4.87e-2)" "unprognostic (4.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (7.71e-2)" "unprognostic (4.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.58e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (8.73e-2)" "unprognostic (3.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.90e-1)" 10.8 9.5 2.6 15.8 3.2 30.3 9.5 3.4 3.6 9.3 3.5 8.6 6.3 4.7 1.5 30.1 4.4 18.1 5.7 2.8 3.9 9.0 37.8 12.1 13.4 5.2 4.0 4.2 7.1 2.7 3.7 7.2 4.8 4.6 9.7 2.3 10.8 3.3 3.0 58.8 8.8 7.3 4.3 7.8 7.1 2.7 4.6 6.5 5.3 2.3 18.3 23.7 17.1 4.5 24.2 4.8 4.0 28.8 13.9 19.7 2.0 75.6 72.9 46.8 46.4 1.0 10.8 0.4 27.2 45.6 23.3 38.3 0.8 48.2 66.3 33.4 0.9 0.0 8.7 2.5 32.1 120.0 10.0 19.1 41.3 63.6 20.9 30.3 51.4 5.1 0.7 13.4 32.9 2.1 2.1 13.5 1.7 3.8 23.6 1.7 10.5 2.1 21.4 27.1 2.3 2.4 15.0 2.3 28.8 3.3 0.8 45.4 79.2 71.0 15.4 8.8 31.1 5.9 1.0 0.1 72.5 69.2 63.0 2.7 44.2 2.0 7.6 34.2 6.8 7.1 6.3 4.7 53.8 9.9 3.3 5.2 12.4 4.6 18.1 28.8 8.9 11.2 2.6 3.2 3.4 3.6 2.8 3.9 5.2 4.0 4.8 4.3 4.6 4.5 6.0 3.2 8.3 0.3 9.1 41.0 25.9 38.9 5.7 0.4 5.5 3.8 1.2 8.6 25.5 0.0 0.0 4.9 13.4 12.3 0.0 30.0 1.3 7.6 3.3 8.7 1.8 3.0 1.8 19.2 5.6 8.6 8.2 16.3 4.5 0.9 7.5 9.6 15.3 0.0 1.3 3.5 12.2 24.8 35.1 1.1 0.9 35.9 16.0 1.0 29.0 1.6 5.2 1.5 2.9 42.2 10.7 0.0 3.5 13.0 8.5 2.9 12.9 0.3 0.0 12.3 9.8 1.7 2.3 18.2 48.4 31.3 8.2 1.4 5.0 33.3 SESN3 "MGC29667, SEST3" ENSG00000149212 "Sestrin 3" P58005 11 95165513-95232541 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 680.7;Late spermatids: 529.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 46.7;ASC TERT1: 50.7;SuSa: 110.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037935 Approved Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA037935: AB_10670534" "unprognostic (2.72e-2)" "unprognostic (3.06e-1)" "unprognostic (2.67e-1)" "unprognostic (8.09e-3)" "unprognostic (5.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.18e-1)" "unprognostic (8.19e-3)" "unprognostic (1.38e-1)" "unprognostic (3.78e-1)" "unprognostic (2.34e-3)" "unprognostic (4.43e-2)" "unprognostic (1.67e-3)" "unprognostic (1.69e-1)" "unprognostic (1.96e-1)" "unprognostic (1.76e-2)" "unprognostic (9.42e-2)" 9.6 17.5 42.3 14.3 56.4 17.9 14.7 24.3 37.8 11.8 26.0 5.7 6.5 11.4 14.1 8.9 8.4 12.4 5.4 32.6 30.7 10.5 7.5 9.1 24.4 21.4 40.6 21.9 3.1 25.8 11.2 7.1 22.5 10.2 6.5 23.4 9.9 5.5 5.3 10.7 12.5 9.2 28.8 17.3 4.9 57.7 54.6 21.8 21.7 13.1 24.2 11.2 8.8 26.6 0.0 1.0 28.2 0.1 46.7 50.7 0.1 0.2 0.0 0.0 0.1 1.2 0.9 7.7 3.4 0.1 1.3 5.7 17.3 12.5 0.0 6.4 9.0 3.9 15.4 1.2 0.9 3.4 0.7 28.1 21.4 0.1 6.3 8.7 1.1 4.5 0.4 1.4 2.3 0.2 2.5 9.0 11.5 0.2 1.2 5.7 1.7 0.6 6.2 19.1 3.6 7.9 0.3 0.2 1.6 110.9 0.0 11.0 0.3 3.2 7.1 0.6 1.1 0.3 0.0 1.0 1.4 4.0 6.9 0.5 0.3 0.2 0.2 0.7 0.3 1.8 0.8 0.5 0.3 1.1 1.6 0.6 0.3 0.3 1.5 0.4 1.7 0.3 42.3 56.4 24.3 37.8 32.6 30.7 21.4 40.6 22.5 28.8 54.6 26.6 13.4 25.6 7.9 152.8 97.6 23.1 26.2 38.3 76.2 48.2 16.1 25.5 7.6 2.8 15.6 35.0 22.9 0.7 7.1 6.9 1.9 6.0 680.7 7.7 45.4 36.4 7.3 73.4 130.8 2.3 0.6 36.5 10.7 14.5 7.0 28.0 35.3 6.4 23.4 0.0 95.1 11.4 8.2 54.8 58.8 529.5 40.7 36.7 32.0 97.4 82.0 98.9 10.3 48.2 37.2 2.2 7.3 87.3 11.9 13.6 27.7 22.5 4.5 14.8 6.6 31.5 28.9 45.4 11.1 38.2 12.5 1.6 41.3 76.4 14.8 14.9 SEZ6L ENSG00000100095 "Seizure related 6 homolog like" Q9BYH1 22 26169462-26383597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 60.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 222.1;Inhibitory neurons: 137.7;Oligodendrocyte precursor cells: 586.1" "Group enriched" "Detected in some" 6 "glioma: 14.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 5.9;myeloid DC: 5.7;non-classical monocyte: 5.3" "Group enriched" "Detected in many" 58 "dendritic cells: 5.7;monocytes: 5.9" "Group enriched" "Detected in some" 6 "SCLC-21H: 39.9;SH-SY5Y: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045135 Approved Vesicles NA NA 6700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA045135: AB_2732518" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (4.49e-2)" "unprognostic (6.47e-2)" "unprognostic (4.19e-1)" "unprognostic (1.09e-2)" "unprognostic (5.02e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-3)" "unprognostic (7.80e-2)" "unprognostic (2.40e-6)" "unprognostic (4.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.39e-4)" "unprognostic (3.18e-1)" 0.1 10.0 25.0 0.5 37.5 0.2 0.0 8.9 50.6 1.1 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 1.3 60.8 52.0 0.0 0.0 0.2 0.0 24.5 23.6 0.0 1.5 0.0 5.8 0.0 19.0 0.2 0.2 4.5 0.2 0.1 0.1 0.3 0.4 0.3 4.0 0.2 1.4 0.3 49.0 0.9 0.1 0.0 0.0 0.1 0.1 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.9 10.7 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 5.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.5 25.0 37.5 8.9 50.6 60.8 52.0 24.5 23.6 19.0 4.0 49.0 24.9 0.0 0.0 0.0 21.9 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.1 0.2 0.0 0.4 222.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.9 137.7 0.0 0.0 0.0 2.1 2.0 0.6 1.5 0.0 10.3 3.5 0.7 0.0 586.1 5.5 0.6 0.0 0.4 0.0 0.1 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SFTPD "COLEC7, SFTP4, SP-D" ENSG00000133661 "Surfactant protein D" P35247 10 79937467-79982614 "Predicted secreted proteins" "Gaseous exchange, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "lung: 507.9" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 2: 1863.1" "Cancer enriched" "Detected in many" 16 "lung cancer: 106.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 10.0;non-classical monocyte: 36.3" "Lineage enriched" "Detected in many" 18 "monocytes: 36.3" "Cell line enhanced" "Detected in some" "BEWO: 1.1;HaCaT: 1.0;hTCEpi: 3.2;MCF7: 1.3;U-2197: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB004578, HPA044582, HPA056768" Enhanced "Secreted in other tissues" NA NA 8200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "CAB004578: AB_628276, HPA044582: AB_2679004, HPA056768: AB_2683232" "unprognostic (3.81e-5)" "unprognostic (7.00e-2)" "unprognostic (1.19e-2)" "unprognostic (1.41e-2)" "unprognostic (4.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.66e-3)" "unprognostic (6.83e-2)" "unprognostic (3.85e-1)" "unprognostic (2.23e-1)" "unprognostic (5.29e-2)" "unprognostic (2.57e-1)" "unprognostic (4.70e-2)" "unprognostic (2.57e-2)" "unprognostic (2.38e-1)" "unprognostic (1.45e-1)" "unprognostic (8.86e-2)" 1.1 1.8 2.2 0.4 2.4 19.7 0.9 1.7 2.5 1.3 2.3 1.0 0.1 0.5 1.3 1.8 1.8 0.9 1.1 2.2 2.4 1.6 1.0 507.9 0.0 1.7 2.0 1.1 4.2 2.0 3.4 0.7 1.8 1.4 0.1 0.3 1.0 1.2 0.2 5.0 0.4 0.4 1.4 0.6 1.1 1.3 2.6 0.5 5.8 0.2 0.2 0.3 2.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.8 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.1 0.3 0.3 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 10.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 36.3 0.0 0.0 0.9 2.2 2.4 1.7 2.5 2.2 2.4 1.7 2.0 1.8 1.4 2.6 1.7 0.3 439.1 1863.1 1.0 0.2 0.9 1.3 7.8 1.2 1.7 1.4 1.8 0.7 0.0 38.0 5.5 0.0 0.1 0.0 0.0 1.9 1.4 7.4 0.6 0.1 1.5 0.0 0.0 4.9 5.8 3.0 4.4 0.0 0.9 20.2 1.6 0.4 0.7 0.1 0.0 3.5 0.0 0.0 0.0 2.7 12.2 1.2 2.9 0.0 1.9 0.6 2.8 0.0 0.0 0.6 2.0 0.1 0.4 0.0 0.8 0.0 0.2 9.6 0.5 0.0 1.8 0.4 0.4 0.3 0.6 1.8 0.1 4.3 0.1 0.1 0.6 SGCA "A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1" ENSG00000108823 "Sarcoglycan alpha" Q16586 17 50164214-50175928 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 155.6;skeletal muscle: 522.4;tongue: 237.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 128.4;Early spermatids: 162.6;Late spermatids: 705.4;Skeletal myocytes: 195.2" "Cancer enhanced" "Detected in many" "prostate cancer: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.4;memory B-cell: 3.3;myeloid DC: 2.2;naive B-cell: 3.3;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 15 "B-cells: 3.3;dendritic cells: 2.2;monocytes: 1.8" "Cell line enriched" "Detected in some" 16 "LHCN-M2: 78.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007537 Uncertain "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA007537: AB_1079944" "unprognostic (1.34e-1)" "unprognostic (2.30e-2)" "unprognostic (1.89e-3)" "unprognostic (1.25e-1)" "unprognostic (9.87e-2)" "unprognostic (2.43e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-2)" "unprognostic (1.15e-1)" "unprognostic (1.91e-1)" "unprognostic (7.01e-2)" "unprognostic (2.57e-1)" "unprognostic (2.07e-3)" "unprognostic (4.96e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-1)" "unprognostic (1.15e-2)" 12.2 1.5 1.8 7.3 2.9 0.0 4.3 3.5 2.2 10.1 1.0 53.7 5.3 36.9 1.6 22.8 18.1 11.9 155.6 1.4 1.5 2.7 4.8 29.7 0.5 1.6 1.5 5.1 1.3 0.8 0.9 6.7 1.8 26.0 3.2 0.1 8.7 27.1 522.4 12.4 14.8 23.0 1.1 3.4 24.1 1.7 1.7 2.3 3.4 237.0 0.4 46.5 11.6 4.7 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.1 0.0 1.4 0.0 3.3 0.0 0.0 2.2 3.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.4 1.8 2.9 3.5 2.2 1.4 1.5 1.6 1.5 1.8 1.1 1.7 4.7 1.1 0.0 0.0 0.0 1.3 8.7 0.5 0.4 0.0 0.6 0.1 0.5 128.4 0.0 0.3 0.0 0.0 0.5 1.4 0.0 0.0 0.6 162.6 0.0 0.2 4.6 0.0 0.0 0.0 5.8 0.1 30.4 0.5 0.0 0.0 0.0 2.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 16.5 705.4 3.1 0.8 8.8 1.9 1.9 0.0 0.0 0.0 0.1 4.1 0.0 3.8 0.1 0.6 0.0 2.1 0.0 0.0 13.1 195.2 48.2 2.3 1.9 0.1 9.9 0.3 0.9 0.0 0.0 0.2 SGCD "CMD1L, DAGD, LGMD2F" ENSG00000170624 "Sarcoglycan delta" Q92629 5 155870344-156767788 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 42.9;tongue: 33.3" "Group enriched" "Detected in many" 4 "Astrocytes: 365.7;Cardiomyocytes: 107.8;Excitatory neurons: 193.0;Inhibitory neurons: 161.2;Microglial cells: 124.6;Oligodendrocyte precursor cells: 417.2;Oligodendrocytes: 196.4" "Cancer enriched" "Detected in many" 5 "melanoma: 10.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 16.1;fHDF/TERT166: 25.7;LHCN-M2: 12.7;RH-30: 18.2;SK-MEL-30: 27.0;U-138 MG: 24.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (2.23e-1)" "unprognostic (3.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (9.55e-2)" "unprognostic (2.63e-1)" "unprognostic (1.66e-1)" "unprognostic (6.53e-2)" "unprognostic (2.25e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-2)" "unprognostic (4.10e-2)" "unprognostic (9.65e-3)" "unprognostic (5.37e-2)" "unprognostic (5.60e-3)" "unprognostic (3.66e-3)" 5.4 4.2 3.2 2.1 2.0 0.0 3.3 1.6 3.6 6.8 0.0 7.9 2.0 8.2 2.5 6.2 2.9 9.3 39.1 2.9 2.7 1.3 2.0 5.0 0.4 4.2 3.8 8.8 1.0 9.9 1.5 0.6 4.3 6.0 3.6 1.6 1.9 5.2 42.9 1.6 2.7 13.4 3.9 1.4 2.9 1.3 2.0 0.7 17.8 33.3 0.5 6.6 3.1 6.6 0.0 6.4 0.0 0.0 5.8 9.2 0.0 16.1 5.5 0.0 0.2 0.0 0.0 0.0 0.0 25.7 0.0 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 8.5 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 3.0 0.1 0.0 0.0 27.0 0.0 0.0 0.0 0.0 24.1 0.0 4.3 0.0 0.1 0.1 0.0 4.1 0.0 9.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.0 1.6 3.6 2.9 2.7 4.2 3.8 4.3 3.9 2.0 6.6 0.7 0.0 0.5 365.7 0.0 3.6 0.0 0.0 0.0 3.5 4.0 2.2 107.8 0.0 0.0 0.0 54.2 0.0 1.6 0.1 0.0 0.1 6.9 6.1 1.5 1.7 1.8 0.0 193.0 0.0 0.0 27.4 0.0 16.3 0.0 11.3 3.3 1.6 0.2 21.9 161.2 0.0 0.0 0.0 2.5 13.3 19.0 0.8 24.9 124.6 0.0 0.3 0.0 417.2 196.4 0.0 0.0 15.4 0.7 0.8 0.0 0.3 0.0 1.2 0.0 38.5 5.9 0.0 0.4 0.5 3.1 0.1 1.0 9.4 0.0 0.2 SGMS1 "MGC17342, MOB, SMS1, TMEM23" ENSG00000198964 "Sphingomyelin synthase 1" Q86VZ5 10 50305586-50625163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.1;Microglial cells: 229.5;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 422.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045191 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA045191: AB_10959605" "unprognostic (1.13e-1)" "unprognostic (5.75e-2)" "unprognostic (1.87e-1)" "unprognostic (9.08e-2)" "unprognostic (8.69e-3)" "unprognostic (8.34e-2)" "unprognostic (7.98e-2)" "unprognostic (2.29e-1)" "unprognostic (1.30e-2)" "unprognostic (5.75e-2)" "unprognostic (9.20e-2)" "unprognostic (2.05e-1)" "prognostic favorable (1.95e-7)" "unprognostic (8.38e-2)" "unprognostic (1.95e-1)" "unprognostic (3.31e-1)" "unprognostic (3.05e-1)" 15.8 19.3 19.8 10.7 27.4 24.0 14.5 21.5 20.3 16.9 33.9 10.1 13.5 11.9 19.9 15.3 16.6 15.4 13.2 17.2 23.0 20.2 27.9 21.9 14.9 29.5 24.1 18.6 13.3 52.9 6.4 24.6 28.5 19.5 11.7 20.2 18.0 16.8 9.9 25.3 16.0 15.8 23.6 11.7 14.3 11.3 23.4 12.0 24.7 10.5 14.5 20.9 13.1 41.3 30.2 14.0 4.0 9.0 14.2 18.6 18.8 19.6 19.7 13.5 12.6 11.7 30.3 22.1 11.3 25.9 12.2 18.7 9.5 20.6 14.0 19.4 10.2 32.7 17.9 9.0 16.5 7.5 7.6 12.1 23.6 18.0 21.7 8.7 19.3 7.9 62.6 32.2 14.6 12.7 3.3 4.2 9.2 13.7 13.7 5.5 18.4 8.8 19.7 31.2 6.2 4.9 14.4 14.2 7.5 11.3 21.4 2.7 27.1 14.6 17.8 14.1 14.6 11.0 9.5 6.3 18.2 12.0 12.1 3.4 9.3 28.4 4.6 4.9 10.3 7.0 6.2 6.8 5.2 6.5 8.2 5.4 16.7 10.1 4.0 3.2 15.6 6.3 19.8 27.4 21.5 20.3 17.2 23.0 29.5 24.1 28.5 23.6 23.4 41.3 17.1 44.8 40.0 106.7 19.9 54.4 28.9 15.6 23.9 20.1 15.8 8.9 26.3 10.0 30.0 29.5 4.2 10.9 15.6 6.2 15.6 17.6 17.0 20.9 10.5 19.6 14.9 32.0 153.1 21.6 7.7 19.8 30.5 32.4 20.8 12.1 17.9 16.0 29.0 5.0 117.2 11.1 4.1 46.5 17.6 30.6 16.1 34.5 12.4 229.5 12.4 17.4 10.3 313.1 422.0 10.7 6.4 10.5 13.7 32.3 18.4 9.3 25.1 36.4 0.0 20.5 27.1 12.8 2.3 18.7 83.4 4.9 20.0 11.8 12.4 25.4 SGPP1 ENSG00000126821 "Sphingosine-1-phosphate phosphatase 1" Q9BX95 14 63684216-63728065 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 61.8;Oligodendrocytes: 60.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 43.8;U-698: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053149, HPA064908" Approved Supported Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA053149: AB_2682057, HPA064908: AB_2797270" "unprognostic (1.57e-2)" "unprognostic (1.04e-2)" "unprognostic (5.40e-3)" "unprognostic (7.82e-2)" "unprognostic (9.09e-2)" "unprognostic (4.30e-2)" "unprognostic (6.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.64e-1)" "unprognostic (7.41e-2)" "unprognostic (1.51e-1)" "unprognostic (3.27e-1)" "unprognostic (8.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-3)" 7.9 10.6 5.3 6.0 6.0 3.0 6.4 5.8 7.9 6.4 3.6 7.0 3.8 7.4 6.2 4.9 5.7 5.5 4.9 5.3 5.9 15.9 19.5 6.9 13.3 6.6 6.2 5.8 12.7 10.2 5.6 12.0 6.6 7.4 5.3 4.1 4.8 4.0 4.2 3.8 8.8 4.8 7.3 9.3 5.5 5.4 5.8 5.8 5.8 2.6 12.9 5.8 6.8 8.0 19.7 6.2 3.0 8.6 10.7 9.9 35.9 15.7 10.9 9.6 10.7 2.7 10.9 43.8 4.5 8.0 8.0 20.3 4.8 9.3 15.3 17.3 5.7 4.0 3.4 4.4 13.1 7.3 12.2 7.3 14.7 8.4 13.2 9.7 4.6 8.2 2.3 1.2 14.1 7.3 8.6 0.1 2.1 3.2 13.1 2.1 8.4 3.5 15.2 9.7 1.8 5.0 11.0 10.2 8.4 9.2 13.3 2.6 5.2 13.2 9.1 9.5 7.9 10.1 6.5 57.4 9.7 0.0 5.8 6.9 0.2 1.7 0.5 1.4 0.5 1.8 0.5 0.3 0.3 0.4 0.8 0.6 0.2 0.3 2.1 0.1 1.3 0.3 5.3 6.0 5.8 7.9 5.3 5.9 6.6 6.2 6.6 7.3 5.8 8.0 5.3 12.8 16.2 22.2 22.6 9.7 6.1 4.1 8.0 4.0 9.4 5.2 3.8 24.3 3.2 51.5 0.0 23.4 10.9 11.9 0.0 6.0 2.4 6.3 12.1 6.5 18.6 9.7 32.6 9.1 27.0 12.8 3.1 10.1 11.4 5.0 6.1 43.6 23.7 10.1 38.5 10.2 2.0 61.8 20.1 1.2 6.2 18.6 17.8 21.5 6.8 8.2 2.1 31.7 60.0 13.2 13.5 17.0 5.7 8.1 3.2 22.7 2.6 5.4 6.6 8.1 11.3 7.4 3.5 4.6 13.5 33.0 10.4 10.3 10.3 5.6 SH2D1A "DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD" ENSG00000183918 "SH2 domain containing 1A" O60880 X 124227868-124373197 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "lymphoid tissue: 262.5" "Group enriched" "Detected in some" 7 "dendritic cells: 77.6;NK-cells: 138.0;T-cells: 108.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 54 "gdT-cell: 120.2;MAIT T-cell: 162.9;memory CD4 T-cell: 90.4;memory CD8 T-cell: 175.8;naive CD4 T-cell: 91.2;naive CD8 T-cell: 108.3;NK-cell: 162.2;T-reg: 125.3" "Group enriched" "Detected in many" 70 "NK-cells: 162.2;T-cells: 175.8" "Group enriched" "Detected in some" 6 "HDLM-2: 101.1;JURKAT: 193.0;Karpas-707: 201.3;MOLT-4: 257.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072265 Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA072265: " "prognostic favorable (2.03e-4)" "unprognostic (1.18e-3)" "unprognostic (4.35e-3)" "unprognostic (9.66e-5)" "unprognostic (1.60e-1)" "unprognostic (1.86e-3)" "unprognostic (9.25e-3)" "unprognostic (3.34e-2)" "unprognostic (1.88e-2)" "unprognostic (2.80e-3)" "unprognostic (9.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.94e-6)" "unprognostic (1.27e-1)" "unprognostic (9.00e-2)" "unprognostic (2.36e-1)" "unprognostic (3.14e-3)" 1.4 1.1 0.0 10.8 0.1 5.4 1.2 0.1 0.2 0.9 0.1 1.6 1.5 0.6 0.6 1.1 0.5 4.1 0.3 0.1 0.1 0.4 2.8 3.2 38.4 0.2 0.1 0.4 0.2 0.2 0.2 0.3 0.1 1.1 1.5 0.0 1.3 0.3 0.3 0.4 2.5 0.6 0.2 14.7 2.7 0.2 0.1 262.5 0.7 1.2 16.6 5.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 101.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 193.0 0.0 201.3 0.0 0.0 257.2 4.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 32.7 33.3 0.0 0.2 0.0 0.0 1.4 0.6 0.1 120.2 0.5 162.9 1.1 90.4 175.8 0.5 0.2 91.2 108.3 2.4 162.2 1.2 0.8 125.3 91.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 1.1 3.2 4.7 0.0 3.0 1.5 0.1 0.0 0.0 0.0 0.7 0.8 0.2 1.5 0.0 0.0 0.0 0.1 77.6 0.0 0.0 0.0 0.0 0.5 0.2 0.7 0.0 7.4 0.1 0.0 0.0 2.0 1.1 0.2 3.8 0.0 3.6 0.9 0.1 0.0 0.0 0.0 0.0 5.6 4.4 0.0 0.0 4.3 5.4 0.0 2.3 0.0 138.0 0.5 0.2 0.0 0.0 0.0 14.1 0.2 0.0 0.5 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.2 1.0 0.1 108.9 0.0 0.0 0.0 SH2D2A "F2771, TSAd" ENSG00000027869 "SH2 domain containing 2A" Q9NP31 1 156806243-156816848 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 33.9;dendritic cells: 139.5;NK-cells: 113.3;T-cells: 103.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 30 "NK-cells: 28.5;T-cells: 66.5" "Cell line enhanced" "Detected in many" "HDLM-2: 46.5;HMC-1: 33.3;Karpas-707: 81.0;RPMI-8226: 24.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.5;hippocampal formation: 1.6" HPA074482 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA074482: " "prognostic favorable (4.96e-4)" "unprognostic (2.76e-2)" "unprognostic (7.50e-2)" "unprognostic (3.03e-3)" "unprognostic (1.14e-3)" "unprognostic (2.73e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (3.08e-1)" "unprognostic (1.64e-1)" "unprognostic (9.34e-3)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.26e-12)" "unprognostic (1.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.79e-1)" "prognostic favorable (1.31e-4)" 3.5 0.9 1.0 11.4 1.1 4.3 1.3 3.8 1.6 1.8 1.9 2.2 2.5 1.7 0.3 1.2 1.5 3.3 2.5 0.9 1.5 2.5 2.2 5.4 9.4 1.9 1.1 0.6 1.0 0.3 1.8 0.8 1.5 2.5 2.0 3.4 0.9 0.7 0.4 0.4 5.4 1.6 1.2 13.0 2.9 0.3 1.1 14.9 1.6 0.0 5.9 3.7 1.2 1.3 2.6 0.4 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 1.7 2.4 0.0 6.8 0.0 0.0 0.0 0.4 1.3 0.1 46.5 0.1 6.8 0.5 0.9 0.2 0.4 33.3 0.5 0.0 0.2 3.3 0.0 0.3 11.8 1.9 81.0 0.0 0.2 5.9 0.7 4.9 4.1 8.3 0.9 0.0 24.5 0.1 0.3 7.5 0.0 1.6 0.9 0.8 0.5 0.2 1.3 2.2 0.0 0.0 0.3 0.5 11.6 16.6 8.3 0.0 6.9 0.2 1.0 0.1 0.0 66.5 0.0 61.8 1.1 27.6 40.8 0.1 0.3 10.4 27.2 1.5 28.5 0.2 0.1 34.1 18.6 1.0 1.1 3.8 1.6 0.9 1.5 1.9 1.1 1.5 1.2 1.1 1.3 1.2 3.2 2.3 0.0 4.6 2.2 0.3 0.4 1.2 33.9 1.0 1.9 0.9 0.0 1.3 0.0 0.0 0.1 139.5 1.2 0.0 0.3 0.2 0.2 2.5 0.6 1.2 6.1 0.0 0.6 1.0 4.8 9.2 0.5 8.2 0.3 1.8 0.9 1.1 0.0 0.0 0.9 0.0 1.9 2.1 0.0 0.0 4.1 0.0 1.9 1.1 1.3 113.3 0.0 0.5 6.1 1.4 0.0 24.2 0.5 0.3 0.2 0.7 1.6 0.0 0.5 2.9 0.1 4.9 3.0 1.3 0.1 103.2 0.1 1.8 0.5 SH3BP4 ENSG00000130147 "SH3 domain binding protein 4" Q9P0V3 2 234952017-235055714 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 83.5" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.0;plasmacytoid DC: 3.1" "Lineage enhanced" "Detected in single" "dendritic cells: 3.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037533, HPA037534" Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" "HPA037533: AB_10672903, HPA037534: AB_2675528" "unprognostic (2.16e-3)" "unprognostic (1.43e-1)" "unprognostic (2.83e-2)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (5.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (3.89e-2)" "unprognostic (1.61e-1)" "unprognostic (4.30e-1)" "prognostic favorable (2.07e-6)" "unprognostic (2.86e-2)" "unprognostic (5.08e-2)" "unprognostic (6.91e-2)" "unprognostic (1.17e-2)" 12.4 9.0 17.8 5.7 21.8 1.1 35.3 21.7 15.9 20.8 20.4 13.8 17.2 12.5 14.5 7.7 17.5 19.0 10.2 14.5 16.2 18.3 26.1 13.2 2.2 21.3 21.1 22.5 61.3 5.8 4.0 18.2 20.5 20.3 13.7 2.4 83.5 16.8 9.5 16.6 11.1 13.6 15.8 5.6 25.6 10.2 19.7 4.7 11.1 9.4 3.8 9.4 7.5 28.1 49.3 30.6 77.7 5.8 33.8 22.4 35.2 70.2 66.6 54.6 48.8 23.5 28.8 0.0 19.0 140.4 126.8 26.1 22.6 47.2 64.8 0.2 10.3 0.0 39.5 64.1 55.8 0.0 0.1 43.9 69.9 76.6 41.4 52.4 58.7 0.1 0.4 0.2 81.4 37.8 0.1 0.2 42.5 56.2 16.8 0.0 16.0 9.3 50.0 9.9 47.9 19.3 15.8 101.4 42.7 55.2 11.9 0.2 47.2 59.8 52.2 47.1 45.7 0.0 0.1 0.2 55.6 0.1 89.2 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.1 17.8 21.8 21.7 15.9 14.5 16.2 21.3 21.1 20.5 15.8 19.7 28.1 23.5 3.2 9.1 4.2 1.0 14.8 50.2 15.6 14.2 2.3 37.3 18.0 6.6 18.6 22.5 7.3 6.2 8.7 3.9 6.0 9.8 24.7 3.4 21.4 10.9 22.9 6.6 1.3 0.7 24.8 29.9 11.7 14.8 29.2 1.3 10.0 17.2 26.8 2.1 3.3 1.4 9.1 16.2 1.4 13.1 4.9 8.1 10.9 24.9 20.6 2.6 1.3 0.0 18.1 52.4 39.6 6.3 9.4 0.2 96.9 0.8 1.9 20.7 0.7 0.0 1.9 12.4 0.8 2.8 8.8 11.1 37.1 0.5 5.5 18.0 30.4 SH3D21 "C1orf113, FLJ22938" ENSG00000214193 "SH3 domain containing 21" A4FU49 1 36306368-36329340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.9;thyroid gland: 27.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 15.3;Late spermatids: 53.6;Proximal enterocytes: 14.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 14.4;HaCaT: 21.1;hTERT-RPE1: 21.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042212, HPA042456, HPA066168" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042212: AB_10961180, HPA042456: AB_10959746, HPA066168: AB_2685627" "prognostic favorable (2.60e-4)" "unprognostic (8.35e-3)" "unprognostic (3.86e-3)" "unprognostic (9.01e-2)" "unprognostic (2.07e-3)" "unprognostic (7.32e-3)" "unprognostic (2.04e-4)" "unprognostic (7.47e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.43e-2)" "unprognostic (7.38e-3)" "prognostic unfavorable (1.76e-6)" "unprognostic (8.88e-2)" "unprognostic (2.25e-1)" "unprognostic (7.99e-2)" "unprognostic (8.59e-2)" 1.1 0.7 2.4 2.5 1.1 1.3 10.8 0.2 6.8 4.4 0.0 3.4 14.0 2.2 1.4 6.9 1.2 2.0 2.0 0.8 0.0 8.8 0.8 3.9 2.0 1.1 0.2 3.5 0.5 0.3 1.7 3.1 1.0 6.7 3.7 3.2 13.4 1.4 0.8 17.4 20.9 1.1 0.0 2.2 2.0 6.8 0.8 0.7 27.8 0.3 3.0 1.3 7.2 0.2 11.2 0.3 2.0 2.2 0.5 1.3 14.4 6.1 0.9 2.8 1.3 7.1 4.3 2.2 5.5 1.6 0.3 21.1 1.4 3.3 2.1 0.9 2.1 2.1 4.8 5.3 1.1 1.2 3.2 0.9 3.0 1.9 1.4 21.7 1.0 4.3 0.4 2.6 1.6 7.3 1.4 1.1 1.2 2.6 2.4 2.3 0.3 1.2 3.7 1.8 4.4 2.1 1.1 11.0 3.4 10.3 0.7 0.3 3.2 1.6 1.2 4.3 1.0 3.3 1.0 2.2 3.9 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 2.4 1.1 0.2 6.8 0.8 0.0 1.1 0.2 1.0 0.0 0.8 0.2 1.1 0.0 2.0 0.3 1.7 3.1 1.7 3.0 1.8 6.9 6.2 4.3 1.4 0.0 1.9 5.5 0.0 2.9 1.9 15.3 1.9 0.6 14.2 2.5 2.0 1.6 0.0 0.0 1.6 0.4 2.2 1.9 4.6 7.7 1.3 2.6 1.1 0.3 7.7 11.8 1.2 2.9 2.0 6.1 7.7 53.6 1.2 5.0 3.6 0.0 2.2 1.2 1.0 0.0 0.2 4.3 5.8 2.6 2.9 2.6 14.9 1.1 2.3 1.2 0.0 0.7 2.1 2.6 1.2 2.4 3.1 5.7 1.3 3.2 1.6 1.3 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHC4 "RaLP, SHCD" ENSG00000185634 "SHC adaptor protein 4" Q6S5L8 15 48823741-48963919 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.6;testis: 10.5" "Cell type enhanced" "Detected in some" "Astrocytes: 16.6;Oligodendrocyte precursor cells: 30.7;Oligodendrocytes: 81.8" "Cancer enhanced" "Detected in some" "melanoma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AN3-CA: 10.0;SK-MEL-30: 19.1;WM-115: 16.5" "Low region specificity" "Detected in all" HPA074146 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA074146: AB_2686667" "unprognostic (4.34e-3)" "unprognostic (1.01e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.05e-3)" "unprognostic (1.23e-2)" "unprognostic (3.47e-2)" "unprognostic (2.59e-1)" "unprognostic (2.21e-2)" "unprognostic (3.80e-2)" "unprognostic (3.71e-1)" "unprognostic (1.04e-5)" "unprognostic (9.84e-3)" "unprognostic (3.26e-2)" "unprognostic (3.49e-2)" "unprognostic (1.36e-2)" 0.5 0.9 12.7 1.0 21.0 0.1 1.6 15.8 18.9 1.0 6.7 2.8 0.3 0.4 0.9 0.5 1.0 1.4 3.3 14.0 14.3 0.3 0.1 0.3 0.3 18.3 16.9 0.5 0.2 0.1 1.0 0.4 19.0 0.7 0.5 0.9 2.1 1.3 0.9 0.6 0.8 0.7 13.6 0.2 0.7 10.5 17.8 0.3 0.3 1.2 0.1 0.4 0.9 36.6 0.0 0.4 1.0 10.0 0.4 1.3 0.0 1.5 2.9 0.6 1.2 0.0 0.3 0.1 2.6 0.6 0.1 0.0 0.2 0.4 0.8 2.2 0.1 0.6 0.0 0.0 1.1 0.0 0.2 1.9 0.0 1.3 0.1 1.3 0.1 1.0 0.0 0.2 1.4 1.9 0.4 0.2 0.1 0.0 3.7 0.2 2.7 0.3 2.1 0.4 0.5 0.8 0.2 0.1 19.1 0.9 0.0 0.1 0.0 0.9 0.5 0.6 1.0 0.9 0.1 0.1 0.8 0.5 16.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 21.0 15.8 18.9 14.0 14.3 18.3 16.9 19.0 13.6 17.8 36.6 0.2 0.0 0.0 16.6 0.0 0.3 0.0 2.3 0.0 0.6 1.6 6.7 2.5 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.0 6.4 2.5 0.4 0.4 0.2 0.0 0.0 9.3 0.0 0.2 1.8 0.0 0.3 0.0 0.0 0.7 0.0 0.1 1.7 6.1 0.0 0.0 0.0 0.4 4.5 1.2 0.1 7.2 1.0 0.0 2.7 0.0 30.7 81.8 0.2 0.0 3.4 0.0 0.0 0.0 0.1 2.6 1.0 0.0 0.5 0.3 6.0 6.3 0.1 0.3 0.8 0.3 0.5 0.0 0.0 SHH "HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS" ENSG00000164690 "Sonic hedgehog signaling molecule" Q15465 7 155799980-155812463 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Hydrolase, Protease" "Disease variant, Holoprosencephaly, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 13.6;stomach 1: 10.5;urinary bladder: 16.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 8.3;Cholangiocytes: 18.6;Collecting duct cells: 9.2;Gastric mucus-secreting cells: 9.7;Hepatocytes: 20.1;Intestinal goblet cells: 8.6;Pancreatic endocrine cells: 11.7;Urothelial cells: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.9;GAMG: 39.8;OE19: 10.2;RT4: 25.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 5500000 "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (7.17e-2)" "unprognostic (7.68e-3)" "unprognostic (6.70e-2)" "prognostic favorable (8.62e-5)" "unprognostic (1.59e-1)" "unprognostic (2.50e-2)" "unprognostic (2.39e-3)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.16e-2)" "unprognostic (3.47e-1)" "unprognostic (1.56e-1)" "unprognostic (1.77e-3)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (3.43e-2)" "unprognostic (2.66e-2)" 0.0 8.7 1.3 0.3 1.2 0.0 0.0 1.6 1.2 4.4 0.3 1.3 1.4 0.4 3.0 0.0 0.1 3.8 0.0 0.8 6.2 3.3 13.6 1.7 0.0 3.3 1.6 0.0 0.2 0.0 0.1 0.0 4.6 1.2 1.0 0.3 0.0 1.2 0.0 0.1 1.4 0.0 1.0 0.0 10.5 0.1 2.6 0.0 0.0 0.0 0.0 16.2 0.3 1.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.2 0.0 8.9 0.0 39.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 10.2 4.0 0.0 0.0 0.0 2.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.3 1.2 1.6 1.2 0.8 6.2 3.3 1.6 4.6 1.0 2.6 1.6 0.0 3.2 7.8 0.0 0.0 0.0 8.3 0.0 0.0 1.5 0.0 0.0 0.7 18.6 1.3 9.2 0.0 0.0 0.0 3.7 0.0 1.2 4.7 5.4 0.5 0.2 0.0 0.0 0.1 0.8 0.2 0.1 9.7 7.6 0.0 0.0 0.4 20.1 0.0 0.0 0.4 8.6 0.0 0.6 0.0 1.7 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.7 0.5 0.4 0.1 1.3 2.5 6.6 0.0 0.1 0.0 0.0 0.1 2.7 0.2 0.0 0.0 0.0 0.0 0.0 3.0 8.3 SHISA2 "bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166" ENSG00000180730 "Shisa family member 2" Q6UWI4 13 26044597-26052016 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 12.4;skeletal muscle: 14.2;thyroid gland: 21.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 13.1;Basal prostatic cells: 14.6;Breast glandular cells: 24.1;Oligodendrocytes: 10.9;Urothelial cells: 19.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 25.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 26.7;JURKAT: 20.8;LHCN-M2: 18.7;NTERA-2: 15.5;RH-30: 46.3;U-2197: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049752, HPA050172" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nuclear bodies, Vesicles" "HPA049752: , HPA050172: AB_2681041" "unprognostic (2.08e-2)" "unprognostic (3.00e-1)" "unprognostic (2.41e-1)" "unprognostic (9.71e-2)" "unprognostic (6.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.30e-4)" "unprognostic (4.03e-2)" "unprognostic (3.10e-1)" "unprognostic (7.45e-2)" "unprognostic (2.17e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.56e-3)" "unprognostic (2.09e-1)" "unprognostic (3.46e-1)" "unprognostic (1.51e-2)" 0.5 0.0 1.1 0.2 2.3 0.1 12.4 1.5 2.0 1.7 0.9 0.1 0.7 0.1 7.8 0.2 0.2 0.5 0.2 2.0 1.5 4.7 0.0 4.3 0.5 1.9 1.5 0.3 0.3 0.1 1.6 0.0 1.6 0.5 0.1 0.0 2.7 0.3 14.2 1.1 0.7 0.1 2.2 0.2 2.1 1.2 1.6 2.5 21.0 1.2 0.7 0.7 0.0 5.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.8 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.4 4.2 1.4 0.0 0.0 1.7 26.7 1.0 20.8 0.0 0.0 18.7 1.2 2.3 0.5 15.5 8.4 8.2 0.0 46.3 0.3 1.7 6.5 0.4 0.0 0.4 0.0 5.4 2.6 0.7 0.2 1.6 0.1 0.7 30.4 7.0 0.0 0.0 0.0 0.0 0.0 4.1 0.8 0.1 0.5 0.1 0.2 0.2 0.1 0.4 0.1 0.0 0.2 1.0 1.6 0.4 0.2 0.3 0.1 0.2 0.1 1.1 2.3 1.5 2.0 2.0 1.5 1.9 1.5 1.6 2.2 1.6 5.4 4.7 0.0 13.1 0.0 0.4 5.4 14.6 2.3 0.6 0.0 24.1 6.2 0.5 0.0 1.5 3.7 0.0 0.3 0.3 0.1 0.0 6.0 2.6 1.0 0.5 5.1 0.0 0.0 0.0 0.2 0.3 2.8 3.1 2.5 0.0 2.4 1.1 0.0 0.8 0.0 1.0 0.1 8.2 0.3 2.3 1.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.5 10.9 1.2 0.0 0.4 0.2 3.9 0.0 0.3 1.1 0.0 0.0 7.6 1.6 0.7 5.1 0.4 1.7 0.1 1.1 0.7 0.0 19.6 SHOX2 "OG12, OG12X, SHOT" ENSG00000168779 "Short stature homeobox 2" O60902 3 158095905-158106420 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 7.8;brain: 26.4" "Cell type enriched" "Detected in some" 6 "Early spermatids: 90.3" "Cancer enhanced" "Detected in many" "glioma: 3.4" "Region enhanced" "Detected in many" "thalamus: 26.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.2;THP-1: 38.7" "Group enriched" "Detected in many" 5 "midbrain: 36.0;thalamus: 54.8" "Group enriched" "Detected in some" 6 "midbrain: 10.6;pons: 16.3;thalamus: 32.1" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.62e-1)" "unprognostic (6.32e-2)" "unprognostic (3.32e-2)" "unprognostic (1.08e-3)" "unprognostic (1.51e-1)" "unprognostic (1.69e-3)" "unprognostic (2.28e-3)" "unprognostic (7.66e-2)" "unprognostic (7.35e-2)" "unprognostic (2.23e-1)" "unprognostic (6.31e-2)" "unprognostic (8.75e-3)" "unprognostic (0.00e+0)" "unprognostic (4.20e-3)" "unprognostic (2.12e-1)" "unprognostic (3.95e-2)" "unprognostic (2.76e-3)" 7.8 0.1 8.9 0.0 0.5 0.1 5.4 0.0 1.1 3.9 0.0 0.1 0.0 0.4 0.1 0.0 0.2 0.2 3.4 0.1 6.1 0.0 0.0 0.2 1.7 10.6 13.0 0.2 0.1 0.3 0.2 0.2 7.0 0.1 0.0 0.0 2.2 0.4 1.3 2.2 0.1 0.0 0.5 0.0 0.2 3.4 26.4 0.0 0.5 0.4 0.3 0.4 1.0 0.2 5.5 0.6 0.3 8.1 24.2 15.3 1.5 8.9 3.4 4.8 8.2 1.8 0.7 1.2 0.2 12.8 9.5 0.1 10.1 0.0 1.9 5.1 2.9 13.7 2.7 0.0 0.0 1.2 10.7 6.9 0.3 4.4 0.5 14.8 0.0 0.7 3.8 0.9 2.1 0.3 0.0 0.7 0.0 0.1 0.5 6.2 7.4 1.4 0.0 0.0 2.7 20.5 1.0 0.2 5.2 0.1 0.2 38.7 0.5 15.0 3.1 16.6 14.8 1.1 2.9 0.9 14.5 7.3 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 8.9 0.5 0.0 1.1 0.1 6.1 10.6 13.0 7.0 0.5 26.4 0.2 3.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.2 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 90.3 0.1 1.7 0.9 0.0 0.0 0.0 0.2 0.7 9.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 1.9 1.2 13.9 2.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 13.1 1.1 8.5 5.7 2.8 0.0 0.4 0.3 0.1 0.0 0.2 0.0 SIMC1 "C5orf25, FLJ44216, OOMA1, PLEIAD" ENSG00000170085 "SUMO interacting motifs containing 1" Q8NDZ2 5 176238367-176345991 "Predicted intracellular proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 47.0" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.2;Inhibitory neurons: 57.4;Spermatocytes: 83.1;Theca cells: 102.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037889, HPA037890" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA037889: AB_2675720, HPA037890: AB_2675721" "unprognostic (1.15e-1)" "unprognostic (9.97e-2)" "unprognostic (3.81e-3)" "prognostic unfavorable (2.32e-6)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.20e-2)" "unprognostic (5.59e-2)" "unprognostic (2.75e-1)" "unprognostic (1.97e-3)" "unprognostic (1.60e-1)" "unprognostic (1.21e-2)" "unprognostic (1.74e-1)" "unprognostic (2.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.53e-1)" "unprognostic (3.59e-2)" "unprognostic (9.20e-2)" 5.3 28.0 6.8 4.0 6.2 3.8 4.3 7.0 6.8 12.0 7.5 7.1 5.8 12.2 9.9 4.3 13.4 4.0 4.1 6.0 7.3 3.9 8.7 5.0 5.3 4.7 5.0 47.0 6.5 6.0 14.1 5.1 5.3 9.6 6.9 4.6 3.7 6.5 12.1 5.4 7.5 8.5 3.9 10.2 10.2 33.5 8.2 6.8 4.0 4.4 5.5 8.4 6.4 5.9 2.8 6.9 21.6 17.2 11.1 11.3 11.2 9.6 8.7 9.8 11.2 25.7 7.3 0.1 11.5 10.7 20.0 2.5 24.2 18.1 11.9 4.8 17.9 12.7 4.7 3.3 24.5 13.7 9.3 7.4 7.1 6.4 12.1 6.9 9.3 4.6 32.6 11.5 11.5 12.5 13.2 12.3 8.2 3.3 7.5 19.2 15.2 16.6 6.8 5.1 14.3 15.0 11.0 1.7 10.6 8.3 6.1 26.4 6.6 11.6 6.2 10.6 8.4 3.1 3.5 18.9 4.3 9.2 6.9 7.2 3.7 7.0 3.3 3.5 4.0 4.4 4.0 2.6 5.2 4.1 3.3 2.7 0.4 7.3 2.8 2.6 2.9 2.7 6.8 6.2 7.0 6.8 6.0 7.3 4.7 5.0 5.3 3.9 8.2 5.9 4.9 9.6 5.6 24.2 12.6 2.9 5.9 3.2 8.6 18.1 2.1 3.0 4.0 2.8 3.4 1.8 4.2 0.4 15.0 8.9 1.9 3.8 46.5 2.9 15.6 3.6 13.2 2.5 49.1 3.6 2.9 9.2 19.9 4.9 0.0 58.2 5.3 7.2 2.2 18.5 57.4 9.9 0.0 5.7 2.0 14.4 29.8 4.2 5.4 30.9 5.7 6.1 11.3 30.7 7.7 4.7 7.8 34.6 5.7 7.1 12.0 1.9 3.0 5.3 32.9 5.6 6.3 83.1 33.8 5.9 2.6 0.8 7.7 102.8 8.9 3.1 SIPA1L3 "KIAA0545, SPAR3" ENSG00000105738 "Signal induced proliferation associated 1 like 3" O60292 19 37907208-38208369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 93.7;Inhibitory neurons: 87.3;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 59.6" "Low region specificity" "Detected in all" "HPA042072, HPA045480, HPA074988" Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA042072: AB_2677832, HPA045480: AB_2679342, HPA074988: " "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.86e-1)" "unprognostic (5.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-2)" "unprognostic (1.31e-2)" "unprognostic (5.48e-2)" "unprognostic (3.11e-1)" "unprognostic (6.05e-2)" "unprognostic (3.15e-1)" "unprognostic (5.43e-2)" "unprognostic (9.26e-3)" "unprognostic (6.45e-2)" "unprognostic (4.94e-2)" "unprognostic (5.36e-2)" "unprognostic (1.96e-2)" 2.2 3.0 6.0 6.6 3.0 2.9 5.1 10.4 16.2 4.8 2.6 10.6 18.4 3.3 1.3 4.9 4.8 3.9 6.2 28.9 2.0 6.4 3.4 5.7 6.8 4.2 4.1 2.9 9.7 3.3 3.2 1.4 3.5 5.3 7.0 5.0 8.4 3.5 6.5 11.1 18.1 1.8 1.6 7.3 9.1 4.3 5.6 3.8 10.0 7.3 5.5 4.3 3.6 5.5 34.4 59.6 7.3 9.3 4.3 4.3 4.9 14.5 12.2 9.4 8.8 20.6 19.5 19.5 12.2 12.4 7.9 7.6 6.7 27.1 10.4 6.7 3.3 5.3 5.5 6.5 8.3 3.7 5.5 3.3 14.1 17.5 37.3 13.9 10.8 5.6 3.9 4.1 16.6 10.6 5.0 5.1 6.0 27.2 15.8 10.8 5.9 2.9 20.7 29.1 17.3 9.3 16.0 27.1 2.2 3.9 18.0 3.5 23.2 15.6 5.5 48.4 22.6 5.4 10.0 6.6 20.1 4.9 20.6 0.1 0.1 0.4 0.1 0.2 0.0 1.1 0.1 0.2 0.1 1.5 0.1 0.5 0.1 0.3 1.5 0.3 0.1 0.1 6.0 3.0 10.4 16.2 28.9 2.0 4.2 4.1 3.5 1.6 5.6 5.5 4.8 6.4 10.1 41.4 24.5 12.0 5.2 10.4 6.2 21.9 22.6 12.1 5.2 22.8 10.8 23.9 14.6 2.1 9.3 93.7 3.9 7.2 4.5 19.8 4.8 5.4 25.2 10.8 61.1 15.3 1.4 3.7 40.2 16.5 2.5 4.8 6.4 23.5 3.5 33.7 87.3 46.3 20.3 5.1 13.9 9.2 2.1 8.3 5.4 50.6 7.1 3.0 5.2 99.5 58.7 13.4 38.7 1.9 12.8 6.6 50.0 21.1 19.1 5.7 6.6 4.5 3.6 1.7 5.1 8.9 16.1 0.8 5.1 1.7 30.4 5.6 SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 5.1;Kupffer cells: 20.0;Macrophages: 9.5;Microglial cells: 14.0;monocytes: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cell line enhanced" "Detected in some" "A-431: 4.7;HBEC3-KT: 4.0;HMC-1: 7.8;hTCEpi: 8.5;HUVEC TERT2: 4.3;THP-1: 7.7;TIME: 3.7;U-937: 8.3" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" 5.6 2.4 1.1 12.0 1.2 6.5 1.6 1.3 1.6 1.8 1.8 1.5 0.9 0.9 0.1 1.8 1.6 3.7 1.4 1.1 1.5 1.1 1.8 7.2 7.0 2.7 2.1 0.5 0.7 0.6 0.6 7.5 2.4 0.9 1.7 0.2 1.3 0.6 0.5 0.9 2.0 4.1 1.6 13.1 1.2 0.5 2.7 1.4 0.7 1.8 3.2 3.9 0.9 2.6 4.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.8 0.0 8.5 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 3.7 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 8.3 0.0 3.0 51.1 31.7 0.1 30.4 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 69.5 0.0 24.4 0.6 0.0 18.9 1.1 1.2 1.3 1.6 1.1 1.5 2.7 2.1 2.4 1.6 2.7 2.6 0.0 0.0 1.1 0.0 0.5 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.1 1.3 0.0 1.4 0.2 5.1 0.0 0.1 0.0 0.0 20.0 3.3 0.0 0.0 9.5 0.0 14.0 8.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.1 0.7 0.3 0.1 0.0 0.6 SIRT2 SIR2L ENSG00000068903 "Sirtuin 2" Q8IXJ6 19 38878555-38899862 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Meiosis, Mitosis, Neurogenesis, Transcription, Transcription regulation" Transferase "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 302.1;tongue: 218.2" "Cell type enhanced" "Detected in all" "Early spermatids: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004573, HPA011165" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Cytosol" Nucleoplasm "CAB004573: AB_2188600, HPA011165: AB_1856900" "unprognostic (2.15e-2)" "unprognostic (2.24e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (7.20e-7)" "unprognostic (3.75e-3)" "unprognostic (1.28e-2)" "unprognostic (2.85e-2)" "unprognostic (2.44e-3)" "unprognostic (2.73e-1)" "unprognostic (4.83e-2)" "unprognostic (2.97e-3)" "unprognostic (1.02e-1)" "unprognostic (1.90e-1)" "unprognostic (3.60e-2)" "unprognostic (1.19e-1)" "unprognostic (8.73e-2)" "unprognostic (1.70e-1)" 43.2 44.0 101.6 11.5 137.5 17.4 39.7 141.1 123.0 41.5 79.4 49.2 12.6 37.2 10.4 42.5 37.2 15.0 76.9 100.7 111.2 35.9 51.5 38.2 13.7 151.0 129.6 49.0 33.4 18.2 31.2 10.5 144.7 32.7 10.2 11.9 41.5 14.9 302.1 48.8 32.4 18.3 121.3 40.1 41.4 43.5 127.6 13.1 34.5 218.2 13.0 41.3 37.8 173.5 16.1 9.8 8.4 20.6 46.7 31.8 5.8 11.3 20.2 17.8 22.7 17.1 10.2 5.4 23.7 21.3 13.2 8.3 14.6 25.1 10.9 25.2 15.6 10.1 10.9 10.9 33.0 7.0 22.4 33.5 29.7 14.4 16.9 21.4 31.9 17.7 10.1 42.0 28.2 8.9 15.4 6.2 1.2 27.6 13.6 19.9 22.8 15.3 14.8 14.9 20.7 9.0 12.9 17.8 13.0 7.0 8.0 19.2 28.9 24.0 5.1 37.2 17.0 16.9 8.8 12.6 18.1 19.0 22.0 48.9 54.7 59.8 44.9 69.1 28.5 24.9 21.9 31.0 42.9 28.9 14.3 23.6 42.7 36.5 56.7 44.0 33.1 51.9 101.6 137.5 141.1 123.0 100.7 111.2 151.0 129.6 144.7 121.3 127.6 173.5 39.5 16.0 19.4 26.1 21.0 51.6 30.3 35.1 35.3 29.7 28.8 29.7 42.1 14.3 27.2 12.9 35.5 36.5 90.8 28.4 37.2 29.0 173.0 24.7 15.4 31.1 17.5 27.1 31.2 17.6 15.2 30.3 44.9 26.5 25.4 29.5 28.5 19.7 66.3 30.3 27.2 24.1 97.6 38.3 51.7 74.8 31.1 37.1 46.2 11.2 20.0 22.6 85.5 76.4 110.8 26.5 23.9 41.0 39.7 14.9 54.0 38.8 30.1 28.2 19.7 113.5 27.9 15.3 7.2 30.1 60.1 42.3 45.8 31.3 18.2 21.5 SIT1 SIT ENSG00000137078 "Signaling threshold regulating transmembrane adaptor 1" Q9Y3P8 9 35649295-35650950 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 95.4" "Cell type enhanced" "Detected in some" "B-cells: 78.9;dendritic cells: 31.2;Plasma cells: 19.8;T-cells: 86.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 46 "gdT-cell: 119.1;MAIT T-cell: 202.7;memory B-cell: 213.6;memory CD4 T-cell: 249.2;memory CD8 T-cell: 223.4;naive B-cell: 192.1;naive CD4 T-cell: 170.4;naive CD8 T-cell: 169.5;plasmacytoid DC: 203.1;T-reg: 352.4" "Group enriched" "Detected in many" 56 "B-cells: 213.6;dendritic cells: 203.1;T-cells: 352.4" "Group enriched" "Detected in some" 5 "Daudi: 113.1;HDLM-2: 70.6;JURKAT: 58.7;U-698: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA018506 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA018506: AB_2669896" "unprognostic (4.28e-3)" "prognostic favorable (6.56e-4)" "unprognostic (8.01e-3)" "prognostic favorable (1.94e-6)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-4)" "unprognostic (1.75e-2)" "unprognostic (9.34e-3)" "prognostic favorable (8.17e-4)" "unprognostic (2.00e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.23e-1)" "unprognostic (1.47e-1)" "unprognostic (8.87e-2)" "unprognostic (6.34e-2)" 0.9 0.7 0.1 19.1 0.1 1.9 0.9 0.0 0.2 0.5 0.1 2.4 2.9 0.5 1.1 0.8 0.5 1.7 0.5 0.1 0.1 0.7 0.7 2.8 50.6 0.3 0.1 0.5 0.2 0.1 0.1 0.2 0.3 0.6 2.2 0.0 2.6 0.3 0.3 0.7 13.2 0.6 0.1 23.6 4.7 0.2 0.6 95.4 0.8 0.1 32.5 3.7 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 113.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.7 0.1 0.0 0.0 0.0 19.1 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.4 0.0 0.1 0.0 0.0 104.4 0.0 0.0 0.0 1.4 1.3 0.7 119.1 0.8 202.7 213.6 249.2 223.4 1.8 192.1 170.4 169.5 4.5 0.8 0.8 203.1 352.4 123.9 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.3 0.1 0.6 0.2 0.9 0.0 0.0 0.0 78.9 5.6 0.0 0.0 1.2 0.0 1.0 1.0 0.2 1.5 0.0 0.0 0.0 0.0 31.2 0.7 0.0 0.0 0.0 0.1 0.1 0.6 0.0 2.7 0.0 0.0 1.9 0.9 2.0 0.0 0.0 0.0 1.4 0.2 5.3 0.0 0.0 0.0 0.0 2.7 7.4 0.0 0.0 3.4 5.4 0.0 2.5 0.0 4.1 0.0 0.0 0.1 0.1 0.0 19.8 0.0 0.0 0.3 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.5 3.7 0.3 86.8 0.0 0.3 0.0 SKA2 "FAM33A, FLJ12758" ENSG00000182628 "Spindle and kinetochore associated complex subunit 2" Q8WVK7 17 59109857-59155260 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059235 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA059235: AB_2683953" "unprognostic (2.67e-1)" "unprognostic (6.42e-3)" "unprognostic (9.69e-3)" "unprognostic (5.93e-3)" "unprognostic (2.07e-1)" "unprognostic (4.44e-2)" "unprognostic (7.70e-3)" "unprognostic (9.81e-2)" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (3.96e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.59e-1)" "unprognostic (1.39e-1)" "unprognostic (4.75e-3)" "unprognostic (1.05e-1)" 19.9 12.6 30.8 20.1 33.4 24.2 11.8 43.3 39.5 18.4 29.1 22.1 18.8 20.3 12.5 24.4 18.1 13.0 34.5 27.8 36.3 21.9 22.4 16.1 33.6 34.3 37.6 16.7 11.5 26.1 14.9 22.9 34.3 16.3 20.0 44.4 10.9 19.9 12.6 13.9 16.8 24.6 37.2 15.8 18.3 12.5 34.4 53.7 25.5 20.4 28.5 20.3 18.1 38.3 217.6 78.6 249.4 85.6 32.4 24.5 76.8 107.1 102.8 163.1 182.5 120.2 122.6 114.1 118.8 87.0 124.3 90.9 162.9 149.3 231.0 197.8 127.4 179.4 142.2 75.1 36.8 142.3 112.5 35.6 63.1 104.8 84.5 64.4 77.2 127.3 114.3 164.5 117.1 297.7 215.4 71.9 66.6 238.3 145.1 114.0 281.3 81.0 121.4 93.2 112.3 96.2 119.1 53.8 66.9 165.4 179.2 112.0 68.0 160.5 153.4 130.5 244.8 111.7 255.6 135.9 85.4 105.3 117.6 26.7 13.1 17.2 18.7 23.5 14.4 18.4 25.6 24.1 15.4 13.7 19.8 22.4 2.4 22.9 38.3 18.3 48.3 12.8 30.8 33.4 43.3 39.5 27.8 36.3 34.3 37.6 34.3 37.2 34.4 38.3 24.8 25.6 18.2 23.2 24.6 21.4 21.6 49.2 25.6 36.1 10.8 17.1 46.3 12.8 26.7 9.2 25.0 62.6 25.8 16.1 39.2 38.3 20.8 22.4 30.2 26.9 10.3 96.8 10.9 25.2 61.7 26.9 30.5 21.0 18.3 26.6 25.4 33.0 46.3 50.5 20.1 23.0 14.2 37.0 22.6 9.4 27.1 28.2 23.2 15.0 42.9 49.3 39.1 15.1 26.3 31.9 24.7 25.6 52.0 8.9 12.8 32.1 26.8 39.4 0.0 13.8 41.5 38.8 30.7 34.1 13.5 30.9 35.0 33.8 35.2 18.9 SKP2 "FBL1, FBXL1, p45" ENSG00000145604 "S-phase kinase associated protein 2" Q13309 5 36151989-36196849 "Cancer-related genes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 37.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 134.4;Extravillous trophoblasts: 227.3;Syncytiotrophoblasts: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 274.7;RH-30: 286.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013491, CAB013533, HPA051196, HPA054633" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "CAB013491: AB_2533074, CAB013533: , HPA051196: AB_2681383, HPA054633: AB_2682550" "unprognostic (2.32e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" "unprognostic (5.74e-2)" "unprognostic (9.56e-2)" "unprognostic (1.52e-2)" "unprognostic (1.21e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.72e-7)" "prognostic favorable (8.57e-4)" "unprognostic (5.06e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (4.77e-15)" "unprognostic (2.50e-2)" "unprognostic (3.73e-1)" "unprognostic (1.63e-1)" "unprognostic (2.19e-1)" 4.9 4.0 3.6 5.8 3.9 11.4 4.9 4.7 4.5 5.9 3.9 6.1 6.3 4.7 4.3 8.3 5.1 2.9 2.5 3.9 3.1 2.3 9.8 4.2 7.9 3.7 3.5 5.2 3.8 2.5 4.0 37.9 3.9 4.0 6.1 4.6 4.0 3.7 2.2 5.7 6.5 4.1 3.9 5.9 4.0 2.6 3.7 12.3 3.1 1.6 8.3 4.7 5.6 5.4 25.4 14.8 35.6 54.3 15.5 20.1 274.7 31.2 25.7 89.5 48.7 83.3 22.8 43.3 10.6 20.0 13.3 28.3 53.3 46.7 71.0 19.2 46.7 23.9 51.4 47.1 6.1 44.8 11.4 18.1 12.2 16.9 8.5 7.7 24.2 40.2 37.9 9.1 31.9 16.4 58.9 26.8 51.5 23.8 24.2 53.7 286.7 28.3 7.2 28.1 45.5 46.8 94.3 27.4 14.1 32.2 22.7 33.3 8.0 31.4 36.1 13.5 24.5 12.4 13.1 50.8 15.2 61.3 21.9 9.2 6.6 13.4 4.2 6.1 6.9 5.2 4.7 4.5 14.0 6.0 6.4 4.6 1.1 6.2 3.2 3.5 4.8 4.7 3.6 3.9 4.7 4.5 3.9 3.1 3.7 3.5 3.9 3.9 3.7 5.4 4.4 22.4 8.9 11.8 8.7 3.7 2.4 7.1 12.0 8.2 3.6 4.2 1.3 1.5 1.7 1.8 10.4 134.4 7.4 2.4 1.9 2.4 0.7 5.2 6.5 6.5 3.0 14.1 22.4 2.9 227.3 11.6 7.1 2.4 2.5 20.9 1.8 11.9 35.0 0.0 13.1 6.0 4.1 9.3 3.1 0.3 4.1 5.3 1.8 12.2 7.6 2.5 9.2 11.6 29.5 2.6 3.4 6.4 10.9 1.0 3.2 1.4 6.2 6.8 0.0 11.5 4.1 1.4 6.4 19.8 4.0 83.9 5.6 11.8 9.6 1.2 SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 18.3" "Cell type enhanced" "Detected in some" "dendritic cells: 97.0;Macrophages: 21.8;NK-cells: 44.3;Plasma cells: 25.8;T-cells: 59.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.5;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.5;NK-cells: 39.2;T-cells: 33.4" "Group enriched" "Detected in some" 7 "HEL: 91.2;JURKAT: 51.8" "Not detected" "Not detected" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 48: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: AB_2682246, HPA058217: AB_2683641" "unprognostic (4.16e-3)" "prognostic favorable (7.36e-4)" "unprognostic (4.52e-4)" "unprognostic (2.30e-6)" "unprognostic (3.37e-2)" "unprognostic (3.79e-3)" "unprognostic (2.15e-3)" "unprognostic (1.13e-2)" "unprognostic (1.32e-2)" "unprognostic (2.84e-2)" "unprognostic (3.22e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.77e-8)" "unprognostic (8.48e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-2)" "unprognostic (6.45e-3)" 1.3 0.6 0.4 5.7 0.6 12.5 0.8 1.6 0.7 0.8 0.3 1.7 2.7 1.0 0.5 0.7 0.9 2.4 0.7 0.4 0.2 0.5 1.5 4.1 10.4 0.7 0.4 0.4 0.4 0.1 0.4 0.6 0.8 0.7 1.7 0.5 1.4 0.5 0.6 0.7 3.1 0.5 0.3 8.0 2.6 0.5 0.6 18.3 0.7 0.2 9.0 2.2 0.6 1.1 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 91.2 0.6 3.4 0.0 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 51.8 0.1 0.2 0.0 0.2 10.9 7.6 0.1 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 2.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.1 7.6 0.1 3.0 0.4 3.8 28.8 0.7 24.1 0.4 23.8 27.1 0.4 0.3 21.8 30.5 4.8 39.2 0.1 48.5 33.4 26.5 0.4 0.6 1.6 0.7 0.4 0.2 0.7 0.4 0.8 0.3 0.6 1.1 0.6 0.0 3.9 0.0 1.6 0.4 0.1 0.0 0.0 0.3 0.5 0.3 0.3 0.0 0.7 0.0 0.0 0.1 97.0 0.6 0.0 0.2 1.1 0.4 0.4 0.4 0.0 8.2 2.2 0.0 0.2 0.5 4.1 0.6 1.3 0.0 0.7 0.1 0.2 0.0 1.7 0.0 0.0 1.6 0.4 0.0 0.3 21.8 0.0 1.9 1.2 0.4 44.3 1.5 1.4 0.3 0.1 0.0 25.8 0.1 0.0 0.1 0.0 0.9 0.0 0.3 0.4 0.0 0.2 0.2 0.1 0.1 59.2 0.0 0.2 0.3 SLAIN2 "FLJ21611, KIAA1458" ENSG00000109171 "SLAIN motif family member 2" Q9P270 4 48341529-48426201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 319.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035824, HPA063599" Approved Enhanced Centrosome,Cytosol NA NA 210000 "Cluster 26: Non-specific - Mitochondria" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Centrosome Cytosol "HPA035824: AB_10602399, HPA063599: AB_2685056" "unprognostic (6.20e-2)" "unprognostic (1.80e-1)" "prognostic favorable (5.77e-4)" "prognostic favorable (7.98e-4)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "unprognostic (1.33e-3)" "unprognostic (2.58e-1)" "unprognostic (1.59e-1)" "unprognostic (2.23e-2)" "prognostic unfavorable (6.71e-4)" "unprognostic (1.57e-1)" "prognostic favorable (1.50e-4)" "unprognostic (1.75e-1)" "unprognostic (5.72e-2)" "unprognostic (1.85e-1)" "unprognostic (8.00e-2)" 24.9 12.6 7.0 14.6 6.6 15.5 17.0 10.5 9.0 21.4 9.0 27.3 13.4 23.6 18.6 38.7 25.7 18.5 40.6 6.1 7.2 18.6 26.7 21.0 16.5 6.9 7.1 22.2 15.1 29.6 7.8 22.2 6.8 25.8 24.0 15.8 19.1 30.2 71.8 32.5 16.3 35.4 6.0 16.3 18.2 40.3 8.1 24.4 20.0 98.8 21.0 26.3 21.9 8.5 32.8 12.7 22.2 22.0 33.9 41.6 15.6 49.3 62.3 43.0 44.5 12.6 26.8 19.4 29.7 56.7 76.7 21.2 91.5 46.1 75.6 16.1 9.5 34.1 17.5 14.4 36.5 31.5 33.4 35.4 67.1 50.0 58.0 32.2 25.8 17.1 22.3 21.1 43.7 16.5 36.4 25.9 9.4 25.7 18.2 20.6 43.1 12.4 38.0 35.4 14.7 18.7 20.0 14.8 21.2 20.4 18.6 22.2 33.0 46.8 44.2 29.9 50.5 28.6 32.1 16.3 36.8 35.2 34.5 9.5 6.5 7.7 6.6 4.7 7.2 5.1 8.1 9.9 6.6 7.5 6.6 7.1 5.8 8.8 7.3 2.3 5.7 3.6 7.0 6.6 10.5 9.0 6.1 7.2 6.9 7.1 6.8 6.0 8.1 8.5 37.2 54.5 38.7 43.8 27.9 84.2 50.6 32.6 38.7 15.8 26.5 19.4 79.6 18.6 32.3 27.6 14.6 29.3 31.7 35.0 21.5 29.9 162.4 145.1 64.7 28.8 25.2 16.6 47.0 34.9 29.1 31.9 28.5 57.4 21.6 20.3 21.8 33.0 21.6 35.3 47.3 34.5 22.4 20.5 31.0 319.2 27.4 29.2 19.6 38.4 37.5 20.7 28.8 54.3 43.1 32.2 27.9 36.9 26.2 53.9 23.4 26.4 85.1 41.0 32.9 54.1 43.1 98.7 48.8 55.0 91.5 75.5 35.0 32.8 25.6 58.3 SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692731-1712344 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.6;Spermatogonia: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA019254: AB_1856951, HPA061670: AB_2684581" "unprognostic (1.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.05e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (2.29e-5)" "unprognostic (5.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.13e-2)" "unprognostic (9.81e-3)" "unprognostic (9.55e-3)" "unprognostic (4.58e-2)" "unprognostic (7.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.07e-2)" 29.9 26.4 38.6 37.6 40.2 114.2 26.7 38.0 65.7 28.4 34.4 30.6 23.9 27.3 32.9 35.9 27.6 21.9 18.4 40.9 43.6 35.1 33.9 27.2 71.7 36.4 39.1 28.0 24.4 24.0 26.7 42.0 39.3 22.8 30.6 17.1 25.6 25.3 22.6 37.7 25.6 28.8 37.7 28.3 26.9 63.1 41.8 53.5 27.3 19.2 69.5 35.0 28.0 41.1 132.7 53.9 76.6 80.7 65.3 70.0 81.9 120.1 92.5 131.4 133.8 120.3 144.7 180.6 67.4 96.0 150.9 77.8 147.0 103.0 154.1 75.4 98.5 215.9 63.3 123.6 82.6 208.3 102.8 55.0 84.7 98.1 67.3 74.4 76.5 108.8 172.7 170.3 163.2 52.8 314.6 200.6 97.4 136.7 108.6 241.1 126.3 105.3 131.0 99.5 86.1 69.3 95.4 59.6 69.5 96.8 99.0 127.7 66.3 108.0 63.8 116.1 180.4 107.4 192.2 428.3 99.6 176.0 106.0 25.7 65.4 47.5 47.1 49.7 43.3 51.6 59.7 64.8 50.6 37.8 50.6 49.6 95.8 46.3 44.8 42.2 77.9 75.4 38.6 40.2 38.0 65.7 40.9 43.6 36.4 39.1 39.3 37.7 41.8 41.1 35.2 16.0 18.8 7.2 96.3 105.2 96.3 38.8 61.5 19.4 35.9 34.0 8.2 27.1 23.6 36.8 25.0 166.3 80.5 28.8 107.6 50.6 75.9 38.8 34.9 36.1 35.9 146.0 14.6 31.3 51.8 49.1 53.5 55.5 23.5 45.9 30.0 27.0 81.3 25.2 15.1 33.6 44.7 36.8 58.6 41.6 44.1 60.3 65.8 6.5 64.4 27.4 43.3 9.0 14.4 38.7 25.3 44.0 94.2 88.6 22.5 55.4 16.3 13.6 13.1 46.3 43.8 263.6 294.0 84.1 105.8 44.7 96.6 33.2 44.1 76.5 SLC10A6 SOAT ENSG00000145283 "Solute carrier family 10 member 6" Q3KNW5 4 86823468-86849384 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.1;skin 1: 13.4" "Group enriched" "Detected in some" 5 "Early spermatids: 59.5;Late spermatids: 191.7" "Group enriched" "Detected in many" 5 "cervical cancer: 3.5;head and neck cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;BJ hTERT+: 1.2;HaCaT: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA016662 Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "HPA016662: AB_1669899" "unprognostic (2.79e-2)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (8.31e-3)" "unprognostic (5.88e-2)" "unprognostic (8.87e-3)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-1)" "unprognostic (3.84e-4)" "unprognostic (1.54e-1)" "unprognostic (2.06e-1)" "unprognostic (9.22e-2)" "unprognostic (5.89e-4)" 5.2 0.3 0.1 0.7 0.3 0.0 2.8 0.1 0.2 3.1 0.0 0.4 0.1 0.5 0.3 9.1 0.6 1.0 0.7 0.1 0.4 0.1 0.1 0.3 0.1 0.2 0.3 0.1 0.7 0.6 0.2 0.1 0.3 0.4 0.3 0.0 1.5 0.2 0.7 13.4 0.2 1.0 0.1 0.2 0.3 4.3 0.9 0.3 1.0 1.1 1.2 0.9 4.7 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.2 0.1 0.4 0.2 0.3 0.3 0.1 0.9 0.7 9.3 0.0 0.0 6.2 0.0 13.8 0.0 0.8 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.5 1.7 1.0 2.6 0.0 0.0 2.5 0.0 0.1 0.6 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.2 191.7 1.5 0.1 0.0 2.8 0.0 0.0 0.0 3.5 4.8 0.1 0.0 0.4 1.2 0.1 0.0 0.0 0.1 0.0 0.0 0.2 1.2 1.2 0.6 6.0 24.9 0.0 0.0 0.0 0.0 0.2 SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 78.6;lymphoid tissue: 46.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 108.0;Kupffer cells: 166.8;Macrophages: 209.4;monocytes: 101.2" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.1;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.1;monocytes: 6.1" "Cell line enhanced" "Detected in some" "HEL: 1.2;HMC-1: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" 14.1 8.5 3.5 7.1 4.3 6.7 4.9 3.9 11.1 2.7 4.7 3.5 0.2 2.2 0.1 1.6 7.4 1.0 8.0 3.3 5.0 3.4 5.1 78.6 0.2 7.4 5.2 1.7 3.2 0.3 3.1 2.7 6.9 3.2 0.0 0.6 3.2 0.1 1.7 1.5 2.2 1.9 5.2 46.6 3.0 0.9 17.3 0.3 2.7 1.3 0.0 7.2 2.4 7.4 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.2 0.2 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.0 0.4 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 6.1 0.6 0.3 4.5 0.2 0.1 0.2 0.1 1.9 0.2 0.3 0.2 4.1 0.2 6.0 0.2 0.2 2.0 3.5 4.3 3.9 11.1 3.3 5.0 7.4 5.2 6.9 5.2 17.3 7.4 1.5 22.4 38.5 1.6 4.1 0.9 4.3 1.9 1.2 3.1 4.5 4.6 8.6 2.8 13.8 9.2 0.0 1.8 3.1 1.8 9.8 1.3 1.8 6.1 2.3 17.0 1.2 1.7 1.3 2.1 7.8 5.8 2.0 2.8 25.3 0.9 6.8 7.3 108.0 1.7 0.9 4.0 6.1 166.8 6.3 0.5 2.1 209.4 1.8 4.7 101.2 12.9 10.3 0.5 1.4 0.4 1.6 0.7 5.6 3.9 2.5 11.7 11.0 3.3 19.7 2.9 4.2 0.8 1.8 2.1 1.0 8.1 6.7 3.3 2.9 3.3 SLC12A8 CCC9 ENSG00000221955 "Solute carrier family 12 member 8" A0AV02 3 125082636-125212864 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 22.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Excitatory neurons: 38.4;granulocytes: 17.8;Inhibitory neurons: 27.8;Intestinal goblet cells: 36.6;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 19.6;HHSteC: 33.6;OE19: 27.6;U-2197: 67.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031123 Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "HPA031123: AB_2301872" "unprognostic (4.74e-2)" "unprognostic (1.46e-3)" "unprognostic (1.39e-1)" "unprognostic (5.91e-3)" "unprognostic (7.35e-3)" "unprognostic (1.79e-1)" "unprognostic (2.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.01e-1)" "unprognostic (7.84e-2)" "unprognostic (3.13e-2)" "unprognostic (1.13e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (7.18e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-2)" "unprognostic (1.78e-2)" 1.5 1.1 2.9 1.2 3.2 0.0 2.3 1.0 3.1 1.4 11.7 3.5 5.6 0.6 3.6 4.1 2.0 8.3 0.6 3.4 2.4 3.2 6.8 2.2 0.6 1.6 2.0 0.3 10.0 4.3 2.2 2.7 1.9 2.8 4.2 0.1 11.9 0.6 0.1 1.3 3.6 0.7 1.0 0.3 4.1 2.3 2.0 0.5 22.9 0.0 0.9 2.1 2.2 2.0 14.7 0.0 2.7 0.0 3.3 4.6 6.7 0.8 2.0 0.9 1.7 19.6 6.8 0.0 1.9 5.6 2.8 8.5 0.0 0.0 0.5 0.0 0.0 0.0 7.2 0.0 33.6 0.0 1.0 8.7 8.3 1.9 0.9 16.3 0.0 0.0 0.0 0.6 1.3 3.9 0.0 0.0 9.3 27.6 0.7 0.0 0.2 0.0 6.8 1.3 4.2 0.0 7.0 8.4 0.1 0.9 15.6 0.4 0.2 0.2 1.3 67.9 0.0 0.1 1.9 5.0 3.3 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.2 1.0 3.1 3.4 2.4 1.6 2.0 1.9 1.0 2.0 2.0 0.2 0.0 0.5 7.2 0.1 1.0 1.3 3.3 3.4 0.0 5.6 4.3 1.1 2.8 2.5 23.9 0.0 0.5 0.1 1.6 0.0 3.9 0.3 0.8 1.4 0.3 5.4 0.0 38.4 3.5 6.5 2.1 7.7 2.7 17.8 1.8 0.0 9.4 0.9 0.0 27.8 36.6 0.0 0.0 0.7 0.5 0.0 0.5 0.0 7.5 2.1 0.0 1.0 31.7 2.0 2.9 3.4 0.0 0.2 6.2 2.6 1.5 0.4 0.0 0.0 0.2 0.7 0.6 0.4 4.3 0.3 3.0 0.8 0.1 5.6 1.0 SLC16A14 "FLJ30794, MCT14" ENSG00000163053 "Solute carrier family 16 member 14" Q7RTX9 2 230034982-230068993 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.6" "Cell type enhanced" "Detected in many" "Adipocytes: 17.0;Excitatory neurons: 18.5;Inhibitory neurons: 21.1;Microglial cells: 45.0;Oligodendrocyte precursor cells: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "eosinophil: 11.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 11.3" "Cell line enhanced" "Detected in many" "HL-60: 24.2;Karpas-707: 15.2;REH: 19.5;RPMI-8226: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040518 Uncertain Approved "Endoplasmic reticulum" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA040518: AB_10794877" "unprognostic (2.99e-1)" "unprognostic (1.74e-1)" "unprognostic (2.63e-1)" "unprognostic (1.74e-3)" "unprognostic (2.20e-3)" "unprognostic (2.01e-1)" "unprognostic (4.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.15e-1)" "unprognostic (5.70e-3)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.03e-3)" "unprognostic (3.51e-1)" "unprognostic (2.39e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" 4.6 3.9 7.9 1.7 7.2 5.6 3.2 8.9 7.7 5.0 2.4 3.7 1.0 3.9 2.3 4.0 3.1 2.8 2.4 7.1 7.2 2.3 2.0 1.9 1.3 5.2 6.1 7.3 0.8 7.0 1.4 1.2 4.7 4.5 4.0 2.5 18.6 3.6 1.0 11.0 1.3 3.8 3.8 5.9 1.4 1.2 9.4 2.2 1.5 2.0 1.5 2.0 2.7 4.7 2.9 1.6 1.3 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.4 0.0 0.5 0.0 0.3 0.1 0.0 0.5 5.1 1.4 0.1 0.0 9.7 0.2 3.1 0.0 0.3 24.2 0.0 0.5 3.6 0.0 0.0 3.9 0.2 4.7 0.0 15.2 0.3 0.0 2.4 2.7 1.0 0.3 2.7 19.5 0.0 17.3 5.6 2.6 6.3 2.3 4.9 0.0 0.1 0.1 7.7 1.9 0.0 0.0 1.3 3.3 2.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 11.3 0.4 0.0 0.3 0.3 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.9 7.2 8.9 7.7 7.1 7.2 5.2 6.1 4.7 3.8 9.4 4.7 17.0 0.0 0.0 2.3 1.5 2.5 0.5 1.9 3.4 3.3 1.2 0.8 3.9 0.0 3.5 0.0 2.1 0.0 0.1 1.8 0.0 0.8 0.0 0.5 2.6 10.8 3.6 0.0 18.5 0.6 0.0 2.3 0.0 0.3 0.0 0.2 4.2 2.1 0.1 3.3 21.1 0.3 4.1 0.3 0.6 0.0 1.2 0.1 1.8 45.0 0.0 1.9 0.0 13.6 1.8 0.8 1.0 3.0 8.4 0.9 0.0 0.3 1.6 1.6 0.0 0.5 1.4 0.2 0.2 6.8 4.7 0.3 1.4 8.4 1.3 0.3 SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 124.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 71.7;Proximal tubular cells: 192.3" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 20.4;BJ hTERT+: 20.7;CAPAN-2: 30.8;HHSteC: 19.2;hTERT-RPE1: 42.6;SK-MEL-30: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" 4.9 2.9 2.7 4.6 3.1 1.0 6.9 5.8 4.4 4.2 15.4 3.6 9.5 3.0 22.4 2.7 4.0 13.7 4.6 3.5 4.1 124.1 16.3 9.2 3.4 4.1 3.1 21.4 0.9 0.4 3.8 28.6 3.9 3.8 1.6 2.3 3.6 5.8 1.3 1.3 11.4 3.4 4.1 2.7 2.7 5.2 3.0 0.6 8.5 3.9 1.1 7.9 3.5 4.2 0.4 9.8 2.3 2.7 6.3 12.9 20.4 5.3 20.7 1.8 5.3 3.1 30.8 0.6 5.7 17.1 0.1 0.5 0.1 1.9 1.9 0.5 2.5 0.5 2.7 3.3 19.2 0.9 0.5 10.0 0.3 3.0 0.2 42.6 4.1 0.8 0.5 1.2 3.3 1.0 0.4 0.6 0.9 0.0 0.3 0.2 1.3 0.1 3.7 0.4 1.2 0.9 0.6 9.8 30.6 9.0 0.7 0.1 0.4 1.4 0.7 0.3 1.5 0.5 0.1 1.6 1.1 0.4 6.1 0.0 0.2 0.1 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 2.7 3.1 5.8 4.4 3.5 4.1 4.1 3.1 3.9 4.1 3.0 4.2 1.9 12.8 20.8 2.3 5.8 3.1 6.1 11.2 1.2 11.5 14.7 6.5 1.1 11.5 6.8 71.7 6.2 39.5 5.8 0.9 3.9 2.7 0.5 3.3 6.8 4.6 3.5 2.7 8.2 0.9 34.6 18.2 1.5 3.3 5.1 5.2 4.2 5.0 4.2 3.3 7.1 0.9 4.1 1.6 3.0 2.2 18.0 1.8 10.6 15.0 1.8 2.4 9.2 2.5 4.7 1.9 1.2 11.7 1.2 3.1 38.4 192.3 3.5 20.1 0.0 4.5 5.4 3.4 1.9 0.5 3.7 35.2 3.9 7.0 1.4 7.2 SLC18A1 "CGAT, VAT1, VMAT1" ENSG00000036565 "Solute carrier family 18 member A1" P54219 8 20144855-20183206 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "adrenal gland: 25.1" "Cell type enriched" "Detected in some" 27 "Enteroendocrine cells: 139.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.8" "Region enriched" "Detected in single" 19 "midbrain: 3.9" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 19 "monocytes: 2.8" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 67.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA006877, HPA063797" Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA006877: AB_2667690, HPA063797: AB_2685125" "unprognostic (8.03e-4)" "unprognostic (1.02e-1)" "unprognostic (3.75e-3)" "unprognostic (3.50e-1)" "unprognostic (6.61e-2)" "unprognostic (3.09e-3)" "unprognostic (1.67e-1)" "unprognostic (2.16e-2)" "unprognostic (3.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.32e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-2)" "unprognostic (8.25e-2)" "unprognostic (4.41e-2)" "unprognostic (2.06e-1)" "unprognostic (1.05e-1)" 0.1 25.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 1.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 3.8 67.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 3.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 139.0 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 SLC18A2 "SVAT, SVMT, VMAT2" ENSG00000165646 "Solute carrier family 18 member A2" Q05940 10 117241093-117279430 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.1;cervix: 30.0" "Cell type enriched" "Detected in many" 5 "granulocytes: 636.0" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 11 "hypothalamus: 20.8;midbrain: 81.1;pons: 70.5" "Immune cell enriched" "Detected in some" 15 "basophil: 59.5" "Lineage enriched" "Detected in many" 15 "granulocytes: 59.5" "Cell line enriched" "Detected in some" 19 "HMC-1: 351.0" "Region enhanced" "Detected in many" "midbrain: 62.7" "Region enriched" "Detected in all" 4 "midbrain: 111.6" HPA073224 Enhanced Approved Vesicles,Centrosome NA NA "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Vesicles, Centrosome" "HPA073224: AB_2732222" "unprognostic (1.49e-1)" "unprognostic (2.48e-1)" "unprognostic (2.33e-3)" "unprognostic (9.00e-2)" "unprognostic (2.85e-1)" "unprognostic (5.33e-3)" "unprognostic (2.23e-1)" "unprognostic (1.71e-2)" "unprognostic (1.40e-1)" "unprognostic (4.55e-2)" "unprognostic (2.00e-1)" "unprognostic (6.06e-3)" "unprognostic (7.94e-5)" "unprognostic (2.95e-2)" "unprognostic (2.31e-1)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" 1.1 14.6 0.1 0.9 1.1 2.4 1.8 0.1 0.3 30.0 0.2 2.3 1.5 2.6 1.6 2.5 0.5 3.6 0.7 0.2 20.8 0.9 2.8 7.4 0.6 3.8 81.1 10.4 3.4 0.2 0.2 0.1 70.5 9.2 3.5 0.4 0.8 1.3 0.8 6.3 2.1 2.3 0.0 0.3 4.4 0.9 5.0 6.1 0.0 0.5 0.9 2.9 7.9 0.2 0.2 1.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.3 0.6 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.7 18.6 0.1 0.2 0.0 1.0 351.0 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 0.7 0.0 0.1 1.0 0.3 0.2 0.3 0.6 0.2 0.4 0.2 0.0 0.2 3.4 0.7 0.3 0.1 0.0 0.2 0.0 0.1 0.3 0.1 2.5 0.3 0.8 0.5 0.4 0.2 0.4 1.9 0.3 59.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.0 0.0 3.8 0.0 2.0 0.1 1.1 0.1 0.3 0.2 20.8 3.8 81.1 70.5 0.0 5.0 0.2 0.0 9.6 16.2 1.0 0.2 1.9 0.0 0.0 0.0 2.1 0.2 0.0 0.3 0.0 2.5 0.0 4.2 0.0 5.7 0.4 0.0 0.0 0.0 13.1 16.1 0.7 8.9 4.2 1.1 0.0 0.0 3.4 4.1 112.4 636.0 2.4 9.7 0.3 0.8 0.0 1.7 0.0 0.0 1.0 3.6 0.2 0.6 3.5 1.8 0.0 0.1 0.4 0.0 0.5 0.6 0.1 0.1 4.9 1.9 3.8 0.0 0.1 0.7 0.8 0.0 0.4 1.3 0.2 2.1 0.0 2.7 0.0 5.6 9.8 0.1 0.1 SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.7;breast: 28.4;placenta: 24.1" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 65.4;Syncytiotrophoblasts: 160.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 13.9;BEWO: 6.2;CACO-2: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" 46.7 0.6 5.0 1.9 3.3 1.2 28.4 4.7 4.3 0.5 1.0 2.6 9.1 0.5 0.1 0.7 0.5 5.7 0.7 3.4 4.4 2.2 13.8 4.1 0.8 5.2 4.2 0.9 1.7 0.1 0.1 24.1 5.4 0.3 1.8 2.2 1.1 0.1 0.9 1.6 5.6 0.4 4.4 0.5 0.5 0.5 5.7 0.2 0.4 0.8 0.4 1.0 0.4 4.0 0.3 0.9 0.2 0.8 13.9 0.3 6.2 0.1 0.2 0.2 0.6 20.2 0.4 0.2 0.1 0.1 4.6 0.4 0.6 0.5 0.8 0.0 1.0 0.1 1.1 0.8 1.8 0.2 0.1 3.4 0.4 0.1 0.8 0.3 0.0 0.3 0.1 0.6 0.0 1.6 0.1 0.5 3.0 0.7 0.1 0.3 0.1 0.2 0.2 0.2 0.9 0.1 0.3 1.9 0.5 2.6 0.2 0.2 0.6 0.4 0.4 4.1 0.4 0.1 0.1 0.6 1.4 0.2 0.5 6.8 0.8 1.0 0.4 0.6 0.3 0.8 0.4 0.4 0.2 1.3 0.5 0.5 3.3 2.2 0.7 1.0 0.2 0.3 5.0 3.3 4.7 4.3 3.4 4.4 5.2 4.2 5.4 4.4 5.7 4.0 0.2 9.6 5.1 2.3 0.0 0.0 0.5 0.0 0.6 5.3 0.2 0.1 0.4 5.7 0.0 1.8 0.0 65.4 0.1 5.7 1.9 4.4 0.3 0.1 0.0 2.6 1.2 0.0 0.4 0.0 7.4 3.2 0.0 0.1 0.0 0.3 0.0 13.1 5.1 0.0 0.9 1.6 0.0 0.6 0.0 0.7 0.3 0.9 0.0 25.3 0.0 0.8 0.0 4.5 0.3 0.4 1.0 0.0 0.1 0.4 9.3 3.0 0.0 0.2 0.0 1.7 1.6 0.0 0.3 0.0 0.0 160.6 0.2 0.1 6.5 0.4 SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 207.7;Cone photoreceptor cells: 70.9;Rod photoreceptor cells: 72.3" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Cell line enriched" "Detected in some" 8 "HHSteC: 21.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" 1.6 0.2 1.5 0.2 1.0 0.0 1.1 1.0 1.5 1.4 0.8 1.0 2.3 1.3 0.0 1.2 1.8 5.2 1.6 1.2 1.1 0.4 1.0 0.6 0.1 1.6 1.9 2.4 0.2 0.4 0.1 0.2 1.8 0.8 0.0 40.2 0.5 0.0 1.3 0.8 3.1 0.0 1.5 0.0 0.8 0.5 2.3 0.0 0.6 3.0 0.0 1.0 1.1 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.0 1.0 1.5 1.2 1.1 1.6 1.9 1.8 1.5 2.3 1.2 1.9 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.6 0.0 0.0 0.0 70.9 0.1 3.0 2.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.2 5.9 4.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 1.0 0.0 0.3 0.0 0.0 1.2 0.5 0.0 7.5 0.0 8.5 16.5 0.0 0.1 0.0 4.0 1.2 0.7 0.0 17.7 0.7 0.0 72.3 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 1.7 0.1 0.3 0.0 SLC22A15 FLIPT1 ENSG00000163393 "Solute carrier family 22 member 15" Q8IZD6 1 115976513-116070054 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.6;brain: 31.8" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 250.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.3;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 8 "granulocytes: 1.3;monocytes: 1.2" "Cell line enhanced" "Detected in many" "hTCEpi: 36.0;hTERT-HME1: 47.4;NB-4: 27.4;THP-1: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019785 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA019785: AB_1857011" "unprognostic (3.81e-1)" "unprognostic (1.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.01e-3)" "unprognostic (5.62e-2)" "unprognostic (5.22e-2)" "unprognostic (5.85e-5)" "unprognostic (8.91e-3)" "unprognostic (1.81e-1)" "unprognostic (4.97e-2)" "unprognostic (5.15e-2)" "unprognostic (9.06e-2)" "unprognostic (7.29e-3)" "unprognostic (8.78e-3)" "unprognostic (3.44e-1)" "unprognostic (9.97e-4)" "unprognostic (1.30e-1)" 3.2 3.1 7.8 2.3 16.5 30.6 1.7 12.3 12.0 3.1 0.9 1.3 1.0 1.1 1.3 5.2 1.5 1.9 4.7 8.6 11.6 3.4 1.1 4.9 0.9 13.3 11.6 1.1 3.1 4.2 2.7 2.0 14.3 1.9 1.7 6.7 4.5 1.6 0.6 9.4 1.9 1.0 11.6 3.4 3.5 1.1 13.1 0.5 2.8 1.0 1.1 1.7 5.0 31.8 3.0 0.2 2.1 0.0 3.7 4.4 1.5 4.7 6.9 2.8 5.0 0.0 0.5 3.3 5.0 2.3 2.4 4.5 3.6 9.7 2.7 0.0 2.3 3.2 3.7 0.5 12.3 4.9 4.3 4.5 36.0 0.1 47.4 0.2 0.0 0.0 0.1 0.0 4.7 2.7 0.0 27.4 3.0 2.8 2.3 0.0 0.0 0.1 3.9 1.6 2.2 1.9 8.1 1.7 13.8 3.1 0.4 29.4 0.0 5.0 2.7 1.0 1.2 4.8 4.8 0.4 5.3 8.0 8.1 0.3 0.8 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 1.2 0.0 0.0 0.1 7.8 16.5 12.3 12.0 8.6 11.6 13.3 11.6 14.3 11.6 13.1 31.8 0.2 0.0 13.7 46.7 2.3 2.8 3.1 3.6 5.2 3.0 0.3 0.4 7.8 0.0 3.2 5.5 10.4 0.6 0.8 0.5 1.9 1.1 1.3 2.5 0.7 0.2 8.4 0.4 44.2 0.4 0.4 4.6 4.6 1.4 1.3 0.6 1.1 0.0 2.8 8.4 33.9 0.3 0.0 9.4 0.5 0.1 0.9 6.9 1.8 9.4 8.7 1.0 1.0 53.3 250.2 1.6 1.2 0.4 0.7 1.1 0.1 0.3 5.2 2.1 0.0 0.4 1.4 0.3 0.7 5.7 3.0 0.0 1.0 1.2 0.5 1.3 SLC24A3 ENSG00000185052 "Solute carrier family 24 member 3" Q9HC58 20 19212642-19722926 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.7" "Group enriched" "Detected in many" 9 "Astrocytes: 134.5;Inhibitory neurons: 327.0;Oligodendrocyte precursor cells: 375.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "basophil: 5.8;eosinophil: 1.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 5.8" "Cell line enriched" "Detected in some" 4 "HMC-1: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043400, HPA045497" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Cytosol "HPA043400: AB_2678462, HPA045497: AB_2679349" "unprognostic (8.74e-2)" "unprognostic (1.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.41e-1)" "unprognostic (7.40e-2)" "unprognostic (2.09e-1)" "unprognostic (2.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.04e-2)" "unprognostic (3.25e-2)" "unprognostic (1.05e-1)" "unprognostic (5.40e-2)" "unprognostic (1.21e-3)" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (6.08e-4)" "unprognostic (7.36e-3)" 10.4 3.1 16.2 4.0 11.7 1.4 4.9 13.3 56.1 17.8 2.7 10.8 3.8 28.3 24.3 20.6 20.0 13.0 1.1 81.7 18.6 1.1 0.7 5.5 1.0 13.6 19.2 14.6 0.7 7.5 1.2 3.0 9.1 10.9 5.4 7.3 4.7 17.5 40.9 7.0 5.0 29.1 10.3 2.4 3.8 1.5 34.8 1.9 3.0 16.9 2.7 8.6 8.9 5.4 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.8 13.3 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 18.2 0.0 0.0 0.7 0.0 75.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 9.0 0.0 0.6 17.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.2 11.7 13.3 56.1 81.7 18.6 13.6 19.2 9.1 10.3 34.8 5.4 0.2 3.2 1.1 134.5 0.1 1.1 1.1 0.4 0.0 19.1 5.0 2.3 0.4 0.0 1.3 1.8 0.0 8.5 0.1 0.3 0.0 0.1 17.0 1.2 29.8 0.4 7.7 3.4 11.8 0.0 0.3 1.9 0.0 1.6 26.6 0.1 0.4 0.0 0.6 1.7 327.0 4.1 0.0 0.0 0.7 18.3 3.7 1.1 0.0 12.2 0.0 3.1 0.0 375.5 2.4 0.2 2.8 4.1 0.4 0.8 0.4 0.0 0.0 2.2 0.0 2.7 3.0 0.5 0.8 2.9 4.1 3.4 0.4 0.1 0.7 3.8 SLC25A17 PMP34 ENSG00000100372 "Solute carrier family 25 member 17" O43808 22 40769630-40819399 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052708, HPA060972" Approved Supported Peroxisomes NA NA "Cluster 6: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Peroxisomes "HPA052708: AB_2681924, HPA060972: AB_2684400" "unprognostic (2.75e-1)" "unprognostic (1.11e-3)" "unprognostic (1.91e-3)" "unprognostic (2.44e-2)" "unprognostic (2.61e-1)" "unprognostic (1.96e-2)" "unprognostic (2.85e-3)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" "unprognostic (1.63e-3)" "unprognostic (8.44e-2)" "unprognostic (2.72e-1)" "unprognostic (5.59e-2)" "unprognostic (8.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" 7.4 12.3 9.4 5.3 9.2 3.3 14.3 9.9 10.7 9.3 11.5 6.3 5.4 13.2 19.6 7.1 11.4 5.7 4.3 9.2 10.2 13.6 16.9 6.6 9.4 9.9 9.6 20.6 8.8 13.6 9.2 10.0 9.7 10.7 7.3 9.2 9.8 5.9 3.9 9.6 6.0 10.5 10.1 7.3 7.8 10.0 10.0 9.3 12.7 3.6 9.7 8.1 7.2 11.2 23.5 13.5 21.0 18.5 12.8 15.9 16.8 20.7 22.7 32.5 35.7 16.5 8.8 26.7 12.2 20.4 17.7 18.6 30.6 16.6 33.4 27.0 41.3 31.1 18.4 21.1 18.3 35.8 16.2 15.3 22.8 28.6 18.4 14.7 19.4 21.4 46.5 12.9 26.5 19.2 22.0 24.2 17.7 33.2 20.6 23.8 32.4 40.3 27.6 19.7 14.2 12.5 42.8 26.6 26.7 20.3 22.0 10.7 11.8 18.5 24.4 16.1 19.2 13.9 29.6 25.7 19.7 18.4 20.4 7.0 3.3 4.2 4.9 3.9 6.9 8.4 5.8 5.5 4.2 7.6 8.2 6.7 1.5 8.3 3.3 5.4 8.6 4.7 9.4 9.2 9.9 10.7 9.2 10.2 9.9 9.6 9.7 10.1 10.0 11.2 8.4 19.2 9.5 23.2 10.9 16.6 16.8 29.8 10.8 12.1 13.6 9.3 4.0 7.2 20.7 12.9 8.4 39.8 8.0 5.8 21.5 17.9 9.6 17.9 16.5 10.4 6.1 11.6 17.3 17.7 31.9 15.9 8.2 14.2 5.1 15.5 8.2 24.8 12.9 11.8 21.5 6.5 26.4 7.9 6.0 16.0 27.1 7.4 16.0 7.5 17.6 7.9 10.3 18.1 28.0 18.1 4.4 26.7 11.9 18.1 8.2 21.1 15.0 7.0 32.9 9.3 11.6 51.0 38.0 11.7 17.2 28.6 9.7 16.4 7.5 14.9 SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 143.8;choroid plexus: 90.7;liver: 111.5" "Group enriched" "Detected in many" 4 "Astrocytes: 195.2;Hepatocytes: 72.8" "Group enriched" "Detected in some" 5 "glioma: 10.6;liver cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.8;BEWO: 8.5" "Low region specificity" "Detected in all" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria Nucleoplasm "HPA068110: " "unprognostic (2.15e-1)" "unprognostic (6.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-2)" "unprognostic (2.72e-2)" "unprognostic (8.70e-4)" "unprognostic (1.44e-1)" "unprognostic (3.92e-2)" "unprognostic (1.67e-2)" "unprognostic (1.29e-1)" "unprognostic (5.24e-2)" "unprognostic (1.62e-1)" 14.4 1.0 130.1 0.3 132.1 0.1 7.2 116.5 141.1 2.5 90.7 2.9 0.3 2.9 0.2 0.3 3.8 0.9 2.8 119.4 123.3 1.9 111.5 1.2 0.3 121.7 129.2 1.2 1.1 0.2 1.5 0.1 112.5 7.8 0.1 1.9 0.5 0.4 6.2 1.2 1.9 0.5 106.5 4.8 1.5 4.2 143.8 0.3 0.6 4.0 0.1 0.8 1.4 110.7 0.3 0.6 2.2 0.4 3.8 0.0 8.5 0.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.5 0.7 0.0 0.0 0.0 0.3 1.0 0.3 0.3 0.5 1.5 0.3 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.3 0.0 0.4 0.1 0.5 2.0 0.9 1.4 2.9 0.8 0.0 0.1 0.4 0.8 0.3 0.2 0.4 0.7 1.6 2.5 1.0 0.1 0.1 0.3 0.2 0.3 0.9 1.2 0.0 1.8 0.2 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.1 132.1 116.5 141.1 119.4 123.3 121.7 129.2 112.5 106.5 143.8 110.7 1.0 28.9 10.3 195.2 0.3 0.0 0.3 0.1 0.6 0.6 0.3 0.0 1.5 5.7 7.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.6 0.4 0.9 1.7 0.0 10.7 2.0 0.0 0.3 4.7 0.0 0.7 6.3 8.5 3.6 72.8 0.3 0.0 3.0 0.3 0.0 4.1 0.3 0.6 0.9 3.9 0.0 10.3 0.1 2.2 1.0 13.0 11.5 0.0 0.0 2.6 0.1 4.3 0.1 0.8 15.8 3.4 0.0 2.7 2.5 4.8 5.9 0.0 0.1 1.8 2.6 2.6 0.0 0.2 SLC25A34 DKFZp781A10161 ENSG00000162461 "Solute carrier family 25 member 34" Q6PIV7 1 15736258-15741392 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "heart muscle: 14.4;intestine: 14.0;skeletal muscle: 37.8;tongue: 47.3" "Cell type enriched" "Detected in many" 5 "Proximal enterocytes: 44.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069806 Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA069806: AB_2686202" "unprognostic (2.06e-1)" "unprognostic (4.72e-1)" "unprognostic (1.15e-1)" "unprognostic (2.43e-1)" "unprognostic (2.58e-1)" "unprognostic (8.08e-3)" "unprognostic (1.98e-2)" "unprognostic (9.92e-2)" "unprognostic (1.55e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-4)" "unprognostic (5.74e-2)" "unprognostic (6.10e-2)" "unprognostic (4.02e-1)" "unprognostic (1.82e-1)" "unprognostic (4.04e-2)" "unprognostic (2.40e-4)" 2.4 4.4 3.7 1.0 3.8 3.4 1.8 6.8 4.8 3.6 2.4 5.7 14.0 3.1 0.8 1.7 2.9 1.5 14.4 3.6 3.4 4.7 5.6 2.4 1.2 3.2 3.1 4.2 4.9 0.6 3.8 1.3 3.5 2.4 2.0 1.9 4.7 0.8 37.8 1.8 13.7 1.1 2.7 3.7 2.2 2.5 3.7 0.5 3.4 47.3 0.5 2.8 2.3 3.6 0.3 0.2 1.5 0.6 0.7 0.3 0.6 0.2 0.1 0.3 0.2 0.6 0.8 0.4 0.3 0.3 0.8 0.3 0.2 0.2 0.3 0.5 0.3 0.7 0.5 0.2 0.2 0.2 0.9 0.3 1.1 0.4 0.1 0.9 0.2 2.0 0.3 1.3 0.2 0.7 1.7 0.9 1.3 0.2 0.4 0.9 1.3 0.4 0.1 0.0 0.3 1.2 0.3 0.4 3.4 1.4 0.7 1.0 0.8 0.7 1.0 1.0 0.2 1.7 1.6 0.3 0.2 0.9 0.6 0.5 0.1 0.1 0.4 0.0 0.9 0.1 0.9 0.6 0.0 0.2 1.2 0.7 0.6 0.6 0.0 0.1 0.4 0.3 3.7 3.8 6.8 4.8 3.6 3.4 3.2 3.1 3.5 2.7 3.7 3.6 0.9 0.0 0.0 6.2 0.4 0.3 0.3 0.6 0.0 2.6 0.5 0.5 2.7 1.5 0.2 0.0 0.0 0.3 0.3 8.8 0.0 0.2 0.3 0.4 1.3 1.2 3.5 0.0 5.1 0.2 0.4 0.8 2.0 1.7 0.0 1.3 2.2 2.3 1.5 3.3 4.6 3.1 0.0 1.9 0.3 1.0 0.9 1.5 0.0 2.8 1.1 1.8 0.0 2.5 1.7 0.3 8.0 0.4 0.0 0.6 44.6 3.7 0.0 1.8 0.0 2.7 0.9 0.6 0.6 1.1 0.1 1.4 0.6 0.4 5.5 0.7 SLC25A35 FLJ40217 ENSG00000125434 "Solute carrier family 25 member 35" Q3KQZ1 17 8287763-8295400 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.9;Syncytiotrophoblasts: 17.4" "Cancer enhanced" "Detected in all" "endometrial cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051720 Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Mitochondria" "HPA051720: AB_2681584" "unprognostic (4.73e-2)" "unprognostic (1.36e-3)" "unprognostic (1.21e-2)" "prognostic favorable (3.37e-7)" "unprognostic (1.61e-2)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (5.27e-2)" "unprognostic (2.58e-1)" "unprognostic (8.30e-2)" "unprognostic (8.96e-3)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-6)" "unprognostic (5.31e-3)" "unprognostic (2.34e-1)" "unprognostic (1.00e-1)" "prognostic favorable (1.91e-5)" 5.7 8.3 2.9 4.9 3.9 6.1 8.6 3.5 4.4 10.0 4.6 7.7 6.1 13.4 7.6 5.4 7.1 5.2 4.8 2.9 3.2 15.0 4.6 6.8 5.0 3.9 4.0 2.9 12.2 6.1 12.8 4.1 4.1 8.7 5.3 4.5 6.4 5.2 2.2 4.5 7.7 4.1 3.3 8.9 12.5 24.5 4.4 5.2 9.1 1.5 3.5 6.0 5.0 4.2 5.0 13.5 2.4 10.0 7.5 2.9 5.5 3.2 2.8 3.4 3.7 1.6 12.4 5.8 3.3 3.7 7.1 11.0 2.8 3.8 1.9 3.2 3.6 4.8 11.1 1.9 2.7 0.7 12.8 5.9 2.1 6.5 1.2 2.5 5.4 6.8 1.4 2.0 2.9 2.7 5.3 2.7 0.8 3.4 4.4 5.8 1.6 2.6 2.6 12.6 1.2 3.0 9.2 5.4 4.1 2.4 12.2 3.6 7.6 2.3 1.7 5.6 2.7 4.3 2.9 2.1 5.9 8.6 6.1 4.1 5.6 7.6 4.0 8.8 3.3 1.9 3.7 4.3 5.7 3.6 1.3 2.5 1.1 2.8 6.5 3.0 4.1 2.5 2.9 3.9 3.5 4.4 2.9 3.2 3.9 4.0 4.1 3.3 4.4 4.2 3.1 0.0 5.4 5.2 3.6 0.8 1.5 1.4 2.8 4.3 6.3 4.1 1.0 5.7 1.8 11.0 8.4 9.2 2.1 3.8 11.7 2.8 3.8 10.2 1.9 2.8 9.0 4.6 0.5 7.1 2.3 3.0 5.1 10.6 5.1 1.3 1.8 2.8 6.7 1.7 0.7 3.0 2.0 6.4 1.5 5.5 1.5 4.2 0.0 4.7 5.8 7.9 3.1 1.0 2.5 3.2 6.0 1.2 3.7 1.9 2.4 7.3 2.0 9.0 0.0 1.1 1.2 20.9 0.8 1.9 0.3 17.4 3.2 9.1 3.1 1.9 SLC25A43 ENSG00000077713 "Solute carrier family 25 member 43" Q8WUT9 X 119399336-119454478 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 30.7;Oligodendrocyte precursor cells: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035188, HPA078530" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA035188: AB_10602400, HPA078530: " "unprognostic (6.05e-3)" "unprognostic (1.48e-1)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (4.99e-3)" "unprognostic (1.59e-2)" "unprognostic (3.26e-2)" "unprognostic (2.74e-2)" "unprognostic (7.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.80e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.06e-8)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "unprognostic (1.96e-2)" "unprognostic (4.92e-2)" 10.6 2.6 3.1 7.3 3.4 1.8 9.3 3.3 4.1 8.2 5.4 14.0 14.2 5.0 3.4 21.4 5.3 4.3 5.0 3.2 3.6 7.7 10.6 10.2 5.5 4.3 3.5 6.0 5.9 6.9 1.9 8.3 3.9 4.6 15.5 0.5 10.8 4.6 1.6 16.3 12.8 8.8 3.5 4.9 8.9 2.1 3.6 3.6 4.2 4.5 11.3 7.9 11.3 3.8 32.4 23.3 1.9 9.2 30.0 44.5 12.2 17.9 21.7 13.8 13.2 12.4 16.0 4.0 10.2 47.4 41.1 23.2 18.2 16.0 12.4 28.5 5.4 11.3 7.4 16.4 19.3 10.6 11.7 18.8 28.3 22.5 19.8 18.9 16.6 6.1 2.3 17.1 15.7 58.9 0.1 15.9 10.3 16.6 35.1 3.2 0.0 4.6 22.3 10.9 1.5 0.0 23.0 47.8 29.1 7.3 8.5 11.0 24.2 22.2 7.1 25.0 28.0 0.4 14.2 8.3 22.3 17.8 19.7 0.0 3.5 0.2 0.9 4.9 1.7 4.4 1.8 2.9 6.0 3.7 0.9 1.8 0.1 6.4 11.2 1.6 1.5 1.6 3.1 3.4 3.3 4.1 3.2 3.6 4.3 3.5 3.9 3.5 3.6 3.8 8.3 6.4 9.7 30.7 8.0 7.8 7.3 8.9 9.6 0.2 6.1 6.6 1.6 2.8 5.6 3.7 0.0 11.9 9.1 21.8 9.8 4.5 0.0 0.9 7.6 6.9 7.3 3.4 10.3 8.9 7.1 11.8 9.7 1.8 8.2 2.1 6.4 5.8 10.3 0.0 6.2 9.6 4.1 7.1 13.6 0.4 8.1 7.5 10.6 1.0 11.9 0.2 9.2 36.7 1.4 13.9 11.4 5.7 2.8 5.4 19.8 9.6 2.0 0.4 0.0 7.8 9.2 0.5 2.3 19.8 13.9 6.8 6.8 1.0 12.2 5.8 SLC26A2 "DTD, DTDST" ENSG00000155850 "Solute carrier family 26 member 2" P50443 5 149960758-149993455 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 212.0" "Group enriched" "Detected in many" 4 "Distal enterocytes: 2026.2;Glandular and luminal cells: 684.5;Syncytiotrophoblasts: 808.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "EFO-21: 66.1;RPTEC TERT1: 151.7;TIME: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041957, HPA058090" Enhanced Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041957: AB_10795646, HPA058090: AB_2683602" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "unprognostic (3.03e-2)" "prognostic favorable (7.29e-4)" "unprognostic (2.59e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.59e-1)" "unprognostic (5.64e-2)" "unprognostic (1.19e-1)" "unprognostic (7.43e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.70e-1)" "unprognostic (1.77e-1)" "unprognostic (8.12e-2)" "unprognostic (1.06e-1)" 5.2 30.7 2.2 7.8 2.3 2.5 9.2 9.5 3.8 6.3 4.0 212.0 12.9 9.3 22.8 10.7 5.0 5.5 2.8 2.2 3.5 4.9 1.7 7.3 4.0 3.8 3.4 4.8 3.4 37.7 7.1 34.0 3.5 12.2 189.6 20.8 35.8 18.4 3.9 7.8 16.1 9.3 3.8 3.7 3.3 4.2 3.9 4.2 4.5 3.7 5.9 4.7 3.0 3.4 9.5 8.6 10.5 17.3 12.6 8.8 2.5 8.9 8.0 7.0 8.5 44.7 5.1 7.4 66.1 9.5 16.8 6.8 10.0 20.5 12.4 6.0 6.4 9.3 6.7 5.2 9.4 17.3 15.2 9.8 11.8 11.7 15.2 17.3 16.8 9.0 2.4 7.1 29.6 3.0 6.6 9.1 3.2 3.2 13.5 9.5 16.3 3.9 151.7 41.6 3.2 8.1 15.6 3.6 27.2 8.1 7.3 10.0 80.4 16.0 11.8 14.2 10.7 5.2 7.3 4.3 14.7 20.6 23.5 4.9 0.5 0.3 0.9 0.3 1.1 0.5 0.5 0.8 0.7 0.5 0.8 0.9 0.3 1.1 1.6 0.7 1.1 0.5 2.2 2.3 9.5 3.8 2.2 3.5 3.8 3.4 3.5 3.8 3.9 3.4 47.4 44.8 11.3 3.3 8.5 4.6 13.2 22.9 7.4 17.1 23.8 14.6 7.8 7.2 24.2 33.1 16.7 219.2 11.5 2026.2 1.9 6.1 32.7 237.0 92.3 29.8 21.1 16.6 5.4 9.9 7.7 21.5 5.1 684.5 90.0 29.6 17.2 2.0 30.4 6.7 7.9 52.5 20.3 15.3 11.8 15.7 17.4 17.4 90.7 17.8 19.6 15.2 15.5 16.6 6.0 12.1 177.4 12.4 15.2 15.1 91.7 5.1 26.6 84.5 0.0 18.7 13.9 8.7 11.4 73.9 5.1 808.9 14.0 26.3 208.9 5.5 SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 157.7;liver: 288.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 265.5;Hepatocytes: 205.7;Proximal enterocytes: 81.0;Proximal tubular cells: 198.9;Respiratory ciliated cells: 70.2" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 30 "basophil: 63.5" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.5" "Cell line enhanced" "Detected in many" "A549: 50.0;HaCaT: 89.3;HL-60: 66.3;OE19: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026089 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" 4.8 16.0 1.7 2.9 2.0 6.5 13.3 1.7 3.2 1.6 9.2 18.2 11.1 0.3 65.9 2.6 10.9 2.3 0.0 2.7 2.4 157.7 288.0 1.7 1.5 0.8 1.1 0.1 7.2 4.1 12.4 17.3 0.8 5.4 16.2 3.4 0.9 1.0 0.0 1.2 21.3 0.8 0.8 0.4 1.8 0.9 2.5 0.5 4.6 0.0 1.7 3.6 1.2 0.7 0.0 50.0 0.0 0.0 0.0 0.0 0.1 0.9 0.4 0.9 1.3 26.2 6.9 0.0 0.6 1.2 0.6 89.3 22.8 0.7 2.3 36.0 27.9 37.5 43.0 23.6 0.5 66.3 25.8 0.0 2.1 0.2 0.1 0.0 0.0 16.9 11.6 0.0 0.0 8.3 1.8 44.5 1.7 101.8 1.8 0.0 0.0 1.8 4.7 45.7 40.4 2.6 8.7 1.1 0.0 1.1 4.7 22.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 21.2 0.0 63.5 0.0 0.9 0.8 0.0 0.7 0.3 0.7 0.8 0.0 0.2 0.1 0.2 0.3 2.0 0.0 0.0 0.9 0.5 1.7 2.0 1.7 3.2 2.7 2.4 0.8 1.1 0.8 0.8 2.5 0.7 0.3 0.0 1.1 0.7 2.2 1.0 1.3 8.7 1.2 1.1 1.1 0.3 0.3 0.0 13.6 9.2 0.0 265.5 1.6 17.2 11.7 0.6 0.7 9.8 0.1 0.8 4.2 8.0 4.9 2.0 7.6 0.9 1.5 0.7 6.3 0.1 3.9 205.7 16.4 1.7 6.6 18.9 10.2 3.2 0.3 0.9 0.3 1.2 0.0 1.0 0.0 0.6 1.0 0.0 0.4 1.4 26.6 0.0 0.8 3.3 81.0 198.9 70.2 1.9 0.0 0.0 1.0 4.4 4.2 5.1 0.3 54.9 4.6 0.2 25.9 4.9 SLC2A4 GLUT4 ENSG00000181856 "Solute carrier family 2 member 4" P14672 17 7281718-7288257 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 98.8;skeletal muscle: 223.6" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 135.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "Hep G2: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" CAB016544 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB016544: AB_629533" "unprognostic (2.53e-1)" "unprognostic (7.40e-3)" "unprognostic (2.27e-1)" "unprognostic (8.12e-4)" "unprognostic (2.40e-1)" "unprognostic (6.28e-2)" "unprognostic (1.70e-2)" "unprognostic (1.66e-2)" "unprognostic (1.35e-1)" "unprognostic (3.83e-2)" "unprognostic (9.66e-2)" "unprognostic (2.24e-2)" "unprognostic (1.34e-3)" "unprognostic (4.23e-2)" "unprognostic (3.10e-1)" "unprognostic (2.30e-2)" "unprognostic (2.07e-2)" 16.9 5.2 1.4 0.2 1.7 1.1 11.2 0.9 1.5 9.2 0.9 53.1 0.8 9.3 1.2 5.9 11.3 0.7 98.8 1.3 1.1 2.6 3.7 2.1 0.2 1.0 1.5 3.2 0.8 3.4 4.4 0.6 1.2 9.9 1.1 0.4 6.3 3.3 223.6 4.1 9.7 4.3 1.0 0.3 11.7 3.3 1.3 0.1 4.5 63.2 0.0 27.0 5.6 1.1 0.0 0.0 0.4 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 1.7 0.9 1.5 1.3 1.1 1.0 1.5 1.2 1.0 1.3 1.1 1.7 0.0 0.0 1.0 0.0 1.8 0.9 0.3 2.2 0.1 1.5 1.3 135.2 0.0 0.2 0.0 0.0 0.3 0.0 1.0 7.9 0.1 16.6 0.2 0.1 3.7 0.0 10.7 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.3 1.8 2.8 0.1 0.0 0.0 0.8 0.0 0.3 0.3 4.8 0.0 0.1 7.2 1.0 0.0 6.0 0.0 0.0 0.0 0.1 1.2 8.6 0.0 0.8 0.8 0.3 0.4 0.4 32.9 7.0 19.8 1.7 2.2 0.5 1.1 1.0 0.1 0.5 1.0 0.7 SLC2A9 "Glut9, GLUTX, URATv1" ENSG00000109667 "Solute carrier family 2 member 9" Q9NRM0 4 9771153-10054936 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 29.3;liver: 21.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 27.4;Proximal tubular cells: 72.6" "Cancer enhanced" "Detected in many" "renal cancer: 6.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 36.9;myeloid DC: 30.5" "Group enriched" "Detected in many" 30 "dendritic cells: 30.5;monocytes: 36.9" "Cell line enhanced" "Detected in some" "HBEC3-KT: 48.1;Hep G2: 23.6;hTCEpi: 19.9;THP-1: 20.5;U-937: 13.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA066229, HPA075669" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA066229: AB_2685639, HPA075669: " "unprognostic (3.21e-1)" "unprognostic (8.99e-3)" "unprognostic (1.25e-2)" "unprognostic (2.01e-1)" "unprognostic (2.14e-2)" "unprognostic (2.56e-2)" "unprognostic (8.94e-2)" "unprognostic (6.94e-2)" "unprognostic (2.86e-2)" "unprognostic (1.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.23e-1)" "prognostic favorable (1.32e-11)" "unprognostic (1.01e-1)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.20e-1)" 1.6 2.6 1.0 2.0 1.2 2.1 4.2 1.3 1.2 2.5 2.7 1.8 10.7 1.4 2.4 5.2 3.5 2.4 2.3 1.1 1.6 29.3 21.4 4.2 2.0 2.3 1.5 1.6 1.0 2.4 1.4 7.6 2.0 3.5 1.6 1.2 16.6 18.8 0.5 2.2 8.4 2.0 1.8 1.8 1.0 0.7 2.0 4.2 2.7 0.5 1.4 6.4 4.0 3.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.1 0.0 0.3 2.4 0.0 3.5 0.7 0.0 7.3 0.0 48.1 0.0 8.2 0.3 0.0 0.0 23.6 1.6 0.1 6.3 3.4 19.9 0.0 4.8 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.3 2.4 0.0 0.4 0.1 1.5 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.5 0.1 0.0 36.9 0.9 0.3 7.6 0.3 0.3 0.3 0.1 30.5 0.1 0.2 0.1 1.1 0.2 0.9 12.2 0.2 9.1 1.0 1.2 1.3 1.2 1.1 1.6 2.3 1.5 2.0 1.8 2.0 3.0 1.4 0.0 0.0 8.1 1.3 0.9 13.4 27.4 6.2 0.0 4.6 6.1 2.4 0.0 5.7 3.7 2.1 18.7 0.5 1.7 3.9 0.5 5.1 4.1 2.1 1.5 0.0 1.3 4.4 1.1 1.8 1.6 1.1 11.5 1.3 0.5 2.2 5.2 10.3 0.0 5.6 0.9 10.2 8.7 3.7 3.4 0.0 8.8 0.0 15.9 4.4 1.2 1.0 10.6 1.1 0.6 0.5 0.4 0.3 2.0 8.1 72.6 3.0 0.4 0.0 4.6 1.6 1.1 1.9 5.4 0.6 8.5 0.9 0.7 2.5 7.7 SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 753.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 477.5;Alveolar cells type 2: 1315.9;Club cells: 179.9;Glandular and luminal cells: 241.3;Respiratory ciliated cells: 217.0" "Group enriched" "Detected in many" 4 "lung cancer: 252.6;ovarian cancer: 191.7;thyroid cancer: 585.2" "Region enriched" "Detected in single" 6 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 82 "BEWO: 32.2;EFO-21: 121.0;RPTEC TERT1: 86.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Lung - Lung function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: AB_10670536, HPA066474: " "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (7.33e-2)" "unprognostic (9.83e-2)" "unprognostic (2.37e-2)" "unprognostic (6.60e-3)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" 0.4 0.8 0.0 0.3 0.0 0.0 19.1 2.1 0.2 66.6 6.9 0.1 16.4 34.6 0.1 1.5 69.8 9.0 0.2 0.1 0.0 16.7 1.2 753.0 0.1 0.0 0.0 1.3 7.3 0.0 2.1 4.8 0.1 1.0 0.0 0.5 90.2 16.8 0.1 2.6 4.3 0.2 0.0 0.7 2.5 2.7 0.3 2.1 33.6 0.0 7.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 32.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 121.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.1 0.0 0.2 0.1 0.1 86.8 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 477.5 1315.9 0.0 0.1 0.0 0.1 79.1 0.0 0.0 41.5 7.5 0.8 34.3 179.9 20.2 0.0 1.4 0.0 0.0 5.9 72.2 5.4 78.6 30.3 2.5 0.0 0.0 0.1 8.5 0.0 2.6 0.0 241.3 29.0 0.0 0.0 0.0 0.2 0.0 0.1 1.2 26.4 0.0 0.0 20.8 1.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 2.5 0.0 0.0 11.8 13.6 3.4 217.0 0.0 0.0 0.0 5.8 2.1 0.1 0.0 0.0 0.3 4.8 0.0 1.8 4.0 SLC35D2 "SQV7L, UGTrel8" ENSG00000130958 "Solute carrier family 35 member D2" Q76EJ3 9 96313444-96383711 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 117.2;Proximal enterocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 103.8;Hep G2: 132.3" HPA064047 Approved Supported "Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA064047: AB_2685182" "unprognostic (3.67e-1)" "unprognostic (5.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.16e-2)" "unprognostic (3.17e-1)" "unprognostic (8.86e-3)" "unprognostic (4.25e-3)" "unprognostic (2.24e-2)" "unprognostic (4.12e-1)" "unprognostic (5.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-2)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (1.44e-1)" 14.7 8.8 13.5 14.4 20.6 11.4 16.4 17.8 20.6 16.5 12.3 49.1 65.1 14.9 12.1 13.7 14.6 20.6 12.2 14.3 16.0 32.1 56.4 19.2 12.4 25.5 19.7 17.3 31.4 16.4 7.2 25.5 22.1 14.2 46.4 4.3 13.0 11.0 3.9 9.4 65.8 13.9 16.6 10.0 43.1 7.2 20.1 7.5 29.5 6.9 11.7 17.2 13.1 27.8 33.2 27.6 15.8 30.2 20.3 37.3 27.9 14.7 30.2 21.6 17.5 60.4 103.8 0.6 24.5 13.5 49.9 47.6 22.2 21.8 18.7 16.4 16.8 11.3 9.8 132.3 32.5 0.1 0.0 32.2 27.6 16.3 48.7 51.0 46.7 0.0 22.3 0.4 23.7 27.2 0.3 0.1 13.2 67.5 28.5 0.1 0.0 0.0 54.4 21.3 5.5 35.9 11.9 24.8 68.5 53.3 16.4 24.7 41.3 14.5 16.2 21.2 13.8 0.0 0.9 0.1 30.2 0.1 20.4 1.2 0.9 0.6 1.3 1.1 1.6 0.7 2.1 2.9 1.2 0.9 0.7 1.4 0.1 1.8 2.1 0.2 3.9 0.5 13.5 20.6 17.8 20.6 14.3 16.0 25.5 19.7 22.1 16.6 20.1 27.8 14.5 9.6 11.0 12.1 4.3 5.2 8.9 2.1 1.8 1.1 15.1 13.1 7.2 27.1 4.6 12.9 2.1 28.1 12.9 61.7 11.7 8.1 0.2 21.0 14.0 12.6 9.6 1.3 0.8 24.5 45.1 9.5 20.4 31.6 4.5 20.0 13.2 43.2 20.5 1.7 1.1 42.0 4.1 23.0 9.7 0.6 10.8 17.7 17.8 20.6 8.9 10.2 7.2 11.1 117.2 25.4 43.5 6.0 6.3 15.5 67.0 23.6 6.7 3.6 13.1 6.8 11.2 1.4 4.4 8.6 5.4 26.5 14.6 7.0 34.9 17.9 SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 132.0;prostate: 83.0;stomach 1: 83.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 546.0;Exocrine glandular cells: 213.4;Intestinal goblet cells: 327.8;Paneth cells: 299.3;Proximal enterocytes: 267.7;Respiratory ciliated cells: 406.7;Undifferentiated cells: 259.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" 0.8 8.2 0.0 2.5 0.0 1.0 5.3 0.0 0.0 22.4 0.0 132.0 100.8 5.9 2.5 2.0 46.9 18.8 0.0 0.0 0.0 32.1 0.4 14.9 0.1 0.3 0.1 1.6 8.9 0.0 16.1 3.5 0.1 83.0 30.3 0.0 42.6 3.9 0.0 1.1 86.8 2.9 0.0 1.6 83.4 0.7 0.0 0.2 1.9 0.0 0.7 11.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 3.7 22.4 36.0 0.0 3.8 0.5 23.0 71.4 0.6 0.3 14.6 6.1 0.4 38.6 180.2 66.2 0.0 0.3 0.5 546.0 3.9 111.2 2.3 127.4 8.9 6.2 46.7 0.0 0.1 213.4 0.5 2.4 208.5 67.5 2.5 1.1 0.4 0.0 0.5 0.0 0.1 327.8 91.6 0.0 0.0 3.2 1.5 2.5 0.0 0.0 1.6 0.7 0.0 0.0 0.0 184.0 299.3 0.4 0.3 142.0 267.7 61.5 406.7 0.6 0.0 0.8 11.9 0.2 0.2 0.5 0.4 0.7 2.3 5.5 259.6 139.4 SLC46A3 "DKFZp686A1775, FLJ42613" ENSG00000139508 "Solute carrier family 46 member 3" Q7Z3Q1 13 28700064-28718970 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 76.0;liver: 96.0" "Cell type enhanced" "Detected in many" "Granulosa cells: 53.2;Hepatocytes: 51.3;Proximal enterocytes: 125.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.0;T-47d: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039930 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Actin filaments" "HPA039930: AB_10673263" "unprognostic (5.16e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" "unprognostic (3.88e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "prognostic favorable (7.09e-4)" "unprognostic (3.13e-1)" "unprognostic (3.33e-1)" "unprognostic (1.26e-1)" "unprognostic (5.69e-2)" "unprognostic (7.35e-2)" "unprognostic (1.14e-1)" "unprognostic (5.60e-2)" "unprognostic (9.14e-3)" "unprognostic (6.47e-3)" 13.8 11.7 5.1 10.2 5.7 2.9 10.0 7.7 5.2 14.7 10.0 19.8 46.7 5.6 11.1 4.0 7.5 23.8 12.3 4.7 5.7 18.2 96.0 11.5 16.3 5.9 6.0 3.9 6.7 23.9 10.2 9.5 6.1 6.5 18.8 15.9 9.0 9.9 8.5 4.2 76.0 8.2 6.6 18.2 7.8 11.0 6.6 11.6 12.5 8.6 11.1 7.0 2.2 5.6 0.0 2.8 0.0 7.6 6.0 2.3 0.2 2.7 15.7 3.0 4.4 0.1 6.6 5.2 4.7 4.0 11.5 0.6 3.5 1.4 4.5 3.9 6.2 3.6 0.0 0.0 11.4 0.0 4.3 9.8 2.9 4.5 7.3 3.0 5.6 15.7 3.9 0.0 14.5 3.0 8.6 0.6 0.3 8.0 2.2 3.5 13.3 0.2 27.0 0.9 1.2 0.4 0.0 14.1 5.7 3.1 20.6 4.6 2.0 1.4 2.7 0.4 16.0 4.0 2.0 0.8 0.9 0.0 2.8 33.1 8.9 3.8 10.3 13.1 8.6 7.4 8.0 10.1 11.7 9.7 11.4 10.8 9.8 7.0 19.4 11.0 10.6 8.7 5.1 5.7 7.7 5.2 4.7 5.7 5.9 6.0 6.1 6.6 6.6 5.6 6.2 0.0 5.4 16.0 14.5 1.9 0.1 7.4 1.8 33.7 15.1 3.3 9.6 17.2 15.6 9.2 8.4 0.6 16.4 49.0 1.9 15.5 4.6 2.1 1.7 12.2 3.6 4.6 11.6 5.6 0.3 6.2 0.0 2.1 25.9 53.2 17.5 51.3 10.8 21.9 13.0 6.8 2.0 32.1 36.6 1.8 1.5 22.5 7.2 16.9 9.3 14.2 12.3 14.6 15.6 3.5 5.3 2.2 6.5 0.6 125.0 10.1 15.4 9.8 0.0 2.8 7.2 2.6 0.9 4.9 1.7 0.7 11.4 16.8 13.9 0.2 SLC7A10 asc-1 ENSG00000130876 "Solute carrier family 7 member 10" Q9NS82 19 33208664-33225850 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 31.8;brain: 12.7;breast: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 40.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 1.9;HHSteC: 1.1;HSkMC: 1.6;THP-1: 3.9;U-2 OS: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041884, HPA057036" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli" "HPA041884: AB_10794494, HPA057036: AB_2683317" "unprognostic (1.85e-2)" "unprognostic (1.69e-3)" "unprognostic (2.79e-2)" "unprognostic (1.79e-6)" "unprognostic (1.16e-1)" "unprognostic (2.08e-1)" "unprognostic (1.31e-1)" "unprognostic (4.98e-3)" "unprognostic (4.64e-2)" "unprognostic (1.96e-1)" "unprognostic (3.28e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-2)" "unprognostic (1.34e-3)" "unprognostic (8.91e-2)" "unprognostic (3.47e-1)" "unprognostic (2.18e-2)" 31.8 0.3 7.9 0.1 9.7 0.0 12.7 10.1 11.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.3 9.2 0.5 0.0 0.0 0.2 8.5 12.4 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 0.5 0.8 0.0 0.1 0.2 0.5 0.0 6.0 0.0 0.1 0.5 12.7 0.0 0.5 0.4 0.3 0.3 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 9.7 10.1 11.1 7.3 9.2 8.5 12.4 8.4 6.0 12.7 5.1 0.1 0.0 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 2.4 0.0 9.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 SLC9A4 NHE4 ENSG00000180251 "Solute carrier family 9 member A4" Q6AI14 2 102473226-102533972 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "stomach 1: 53.8" "Group enriched" "Detected in some" 12 "Collecting duct cells: 25.8;Gastric mucus-secreting cells: 54.0" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.3;OE19: 6.8;RT4: 4.1" "Group enriched" "Detected in some" 18 "hippocampal formation: 10.6;olfactory bulb: 6.8" "Low region specificity" "Detected in single" HPA036096 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Plasma membrane" "HPA036096: AB_2674939" "unprognostic (1.41e-1)" "unprognostic (3.76e-2)" "unprognostic (9.31e-2)" "unprognostic (3.09e-3)" "unprognostic (7.58e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (5.35e-1)" "unprognostic (9.44e-3)" "unprognostic (3.26e-2)" "unprognostic (1.30e-1)" "unprognostic (2.46e-2)" "unprognostic (3.12e-1)" "unprognostic (5.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.98e-2)" 0.0 0.0 0.4 0.1 0.5 0.8 0.2 0.7 0.7 0.3 0.0 0.0 2.0 0.1 0.1 1.5 0.1 1.2 0.6 0.4 0.4 8.6 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.4 1.3 0.5 1.4 0.4 0.0 0.0 0.0 0.2 53.8 0.3 0.2 0.1 0.1 0.0 0.5 0.4 0.1 0.6 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 1.3 0.0 0.1 0.1 0.0 0.0 0.0 2.3 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.5 6.8 0.2 0.0 0.2 0.1 0.0 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.7 0.7 0.4 0.4 0.1 0.1 0.2 0.0 0.2 0.6 0.0 3.2 3.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.4 0.0 0.9 25.8 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 54.0 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 2.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.6 0.8 0.0 0.0 0.1 0.4 0.0 0.3 0.3 SLC9A9 "FLJ35613, NHE9" ENSG00000181804 "Solute carrier family 9 member A9" Q8IVB4 3 143265222-143848485 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 149.8;Inhibitory neurons: 159.5;Microglial cells: 396.3;Oligodendrocyte precursor cells: 272.9;Oligodendrocytes: 431.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 19.3;ASC TERT1: 24.9;HSkMC: 17.6;Karpas-707: 62.8;RPMI-8226: 30.4;U-266/70: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058234 Approved NA NA 280000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA058234: AB_2683648" "unprognostic (8.22e-2)" "unprognostic (6.88e-2)" "unprognostic (7.23e-3)" "unprognostic (1.65e-1)" "unprognostic (3.65e-2)" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.18e-4)" "unprognostic (2.66e-1)" "unprognostic (1.35e-3)" "unprognostic (7.73e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (5.57e-7)" "unprognostic (5.01e-2)" "unprognostic (4.69e-2)" "unprognostic (1.56e-1)" "unprognostic (4.28e-2)" 12.8 5.1 9.7 8.8 14.4 2.0 5.3 12.5 11.3 6.9 6.9 7.3 3.0 4.2 3.7 12.8 6.8 9.6 5.4 9.9 16.3 2.3 7.1 5.9 14.7 20.4 13.5 7.9 1.0 3.0 3.4 15.9 19.5 8.8 5.8 1.3 4.5 8.5 2.1 7.7 7.0 8.0 14.4 13.1 5.0 1.8 13.8 15.5 3.5 5.0 13.5 11.4 7.7 18.2 0.5 0.5 0.8 1.0 19.3 24.9 0.3 1.0 6.6 0.5 3.1 0.0 0.2 3.0 0.2 2.9 1.5 0.7 0.9 1.9 0.8 12.8 0.2 1.6 0.4 0.0 2.2 0.8 1.3 17.6 5.2 0.7 0.9 1.1 0.3 2.3 0.0 62.8 4.2 0.0 1.5 0.0 0.2 0.0 0.5 2.6 0.1 30.4 0.0 0.5 0.4 0.0 1.5 0.0 0.0 0.4 0.2 0.6 0.0 2.4 0.6 2.8 1.4 29.1 0.1 0.1 4.3 0.4 1.2 0.2 6.2 0.7 4.7 10.6 4.0 3.3 4.9 7.5 8.4 3.7 2.7 4.0 0.5 4.2 9.0 0.6 9.3 4.8 9.7 14.4 12.5 11.3 9.9 16.3 20.4 13.5 19.5 14.4 13.8 18.2 4.5 0.0 1.1 149.8 13.2 3.7 10.4 8.7 22.8 0.2 0.6 1.3 1.5 0.0 3.4 3.7 2.1 0.5 10.4 0.0 0.0 1.0 4.8 0.8 10.1 4.4 0.0 9.9 25.6 0.2 0.5 26.5 7.1 0.8 0.0 0.7 21.8 0.0 55.4 0.0 159.5 0.0 6.1 30.5 9.9 4.4 9.3 31.0 7.2 396.3 24.3 2.8 13.4 272.9 431.8 0.8 0.1 7.2 10.9 11.1 0.0 0.4 1.6 0.1 0.0 18.0 7.0 0.3 0.4 23.9 5.1 1.1 19.7 3.7 0.1 3.9 SLCO4C1 "OATP-H, OATP4C1, OATPX, SLC21A20" ENSG00000173930 "Solute carrier organic anion transporter family member 4C1" Q6ZQN7 5 102233986-102296284 "Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 41.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 49.7;Early spermatids: 21.6;NK-cells: 26.8;Proximal tubular cells: 32.8" "Cancer enriched" "Detected in many" 5 "renal cancer: 22.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 9.5;neutrophil: 9.8" "Group enriched" "Detected in many" 5 "granulocytes: 9.8;NK-cells: 2.6;T-cells: 3.8" "Cell line enhanced" "Detected in some" "Karpas-707: 17.5;RPTEC TERT1: 98.8;U-937: 25.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058249 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA058249: " "unprognostic (1.63e-2)" "unprognostic (2.47e-2)" "unprognostic (4.48e-4)" "unprognostic (5.70e-6)" "unprognostic (7.43e-2)" "unprognostic (7.71e-3)" "unprognostic (3.24e-3)" "unprognostic (2.05e-3)" "unprognostic (2.13e-1)" "unprognostic (7.12e-2)" "unprognostic (3.87e-3)" "unprognostic (5.83e-2)" "prognostic favorable (1.12e-4)" "unprognostic (3.29e-2)" "unprognostic (1.07e-1)" "unprognostic (5.91e-2)" "unprognostic (8.22e-2)" 0.4 0.8 0.2 0.6 0.3 8.6 0.5 0.0 0.4 0.3 0.0 1.0 2.2 0.1 0.2 0.1 0.2 2.3 0.3 0.2 0.0 41.6 7.6 7.8 0.5 0.2 0.0 0.1 0.4 0.1 0.2 0.1 0.2 0.0 0.8 0.1 2.0 3.6 0.1 0.3 1.5 0.1 0.0 1.3 0.6 0.8 0.3 1.0 1.6 0.1 0.2 0.2 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.7 1.1 0.0 1.0 0.2 1.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 17.5 0.0 1.3 0.1 0.3 0.8 0.0 0.0 0.0 0.0 1.2 98.8 0.1 0.7 0.5 0.0 0.3 0.0 2.3 0.0 2.4 0.0 0.0 0.7 0.0 0.0 1.6 0.0 0.0 0.0 25.8 0.1 9.5 1.0 7.3 3.8 0.0 0.3 0.0 0.6 2.1 0.4 0.1 0.2 1.3 9.8 2.6 0.0 0.2 0.0 1.0 0.2 0.3 0.0 0.4 0.2 0.0 0.2 0.0 0.2 0.0 0.3 0.3 0.1 6.4 49.7 0.3 0.6 0.0 0.1 1.2 0.0 0.0 1.8 0.3 0.3 1.5 6.4 5.5 0.0 0.0 9.6 1.4 1.9 0.2 21.6 0.0 0.1 0.3 0.0 5.7 9.1 0.8 0.0 0.3 0.0 1.6 5.7 0.0 0.4 11.0 0.2 0.0 6.6 0.1 2.0 0.6 0.3 2.6 0.3 2.4 0.0 1.0 3.2 0.0 26.8 1.5 0.3 0.3 0.1 0.0 1.4 0.0 1.8 32.8 3.1 0.0 0.0 0.1 0.1 2.5 2.4 0.0 0.0 0.0 3.4 0.1 1.1 0.4 SLFN11 FLJ34922 ENSG00000172716 "Schlafen family member 11" Q7Z7L1 17 35350305-35373701 "Predicted intracellular proteins" "Antiviral defense, DNA damage, Immunity" "Helicase, Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 70.6;dendritic cells: 39.9;Endothelial cells: 38.8;Langerhans cells: 53.0;Macrophages: 47.0;Smooth muscle cells: 38.8;T-cells: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 118.2" "Low region specificity" "Detected in many" "HPA023030, HPA062062" Uncertain Supported Nucleoplasm,Cytosol No NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA023030: AB_1856613, HPA062062: AB_2684673" "unprognostic (1.93e-2)" "unprognostic (2.56e-1)" "unprognostic (3.04e-2)" "unprognostic (1.03e-2)" "unprognostic (3.48e-3)" "unprognostic (1.01e-1)" "unprognostic (5.19e-2)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (9.93e-10)" "unprognostic (1.65e-1)" "unprognostic (5.71e-3)" "unprognostic (6.33e-2)" "unprognostic (8.81e-3)" 31.7 8.2 5.6 20.0 6.1 12.8 17.1 6.4 5.2 21.1 8.2 10.2 6.2 12.1 42.2 8.4 20.6 18.3 20.0 6.0 8.0 6.4 6.8 37.7 21.2 9.5 6.3 23.1 5.4 6.1 6.5 10.5 9.7 9.1 11.1 1.4 11.8 12.3 7.3 5.2 13.9 19.1 7.6 23.3 9.0 2.7 11.0 22.9 24.1 19.0 20.9 17.9 12.6 9.4 29.3 25.6 0.1 0.0 25.4 72.0 0.4 35.3 25.2 59.9 103.9 0.0 0.0 0.2 0.6 46.4 18.8 13.9 78.8 0.0 72.1 16.6 94.2 63.0 0.3 0.0 33.0 82.4 0.1 29.5 0.9 66.5 0.2 0.0 99.4 46.8 0.1 0.3 10.1 0.0 118.2 66.4 0.6 0.0 0.1 98.9 73.3 0.2 0.7 13.8 0.2 0.1 0.0 13.0 0.1 0.0 20.7 58.6 52.1 16.3 0.4 61.9 53.7 2.3 1.0 0.2 12.2 70.3 36.0 0.5 18.2 2.1 6.1 27.6 8.4 4.6 3.8 5.5 14.0 1.5 2.8 4.1 1.4 3.1 18.2 19.4 6.3 8.7 5.6 6.1 6.4 5.2 6.0 8.0 9.5 6.3 9.7 7.6 11.0 9.4 70.6 0.0 5.2 0.3 19.5 7.5 1.1 1.1 5.7 0.4 6.7 2.8 9.2 1.5 2.7 1.8 0.0 1.4 39.9 0.1 0.0 0.0 1.4 5.9 16.0 38.8 0.0 9.9 0.3 0.6 0.5 29.2 6.6 2.2 3.8 0.3 15.0 0.4 32.8 0.0 2.6 0.1 0.0 36.5 53.0 1.7 10.2 47.0 12.4 17.8 17.2 0.3 3.1 0.0 0.1 0.1 1.2 3.0 24.7 1.3 0.1 0.2 13.3 0.1 6.6 7.9 38.8 0.0 0.2 1.9 8.5 0.8 37.3 7.7 0.1 0.7 SLITRK4 DKFZp547M2010 ENSG00000179542 "SLIT and NTRK like family member 4" Q8IW52 X 143622790-143636101 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.1;brain: 9.0;skeletal muscle: 8.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.3;Granulosa cells: 33.9;Inhibitory neurons: 48.8;Leydig cells: 49.7;Oligodendrocyte precursor cells: 29.7;Sertoli cells: 26.3" "Cancer enriched" "Detected in many" 4 "renal cancer: 3.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 11.6" "Group enriched" "Detected in many" 64 "dendritic cells: 3.2;granulocytes: 11.6;monocytes: 4.1" "Cell line enhanced" "Detected in some" "HeLa: 5.4;HHSteC: 2.7;LHCN-M2: 2.0;T-47d: 8.8;U-2 OS: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000431 Enhanced NA NA 420000 "Cluster 38: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000431: AB_2665991" "unprognostic (1.72e-1)" "unprognostic (2.11e-2)" "unprognostic (2.63e-2)" "unprognostic (1.15e-3)" "unprognostic (4.09e-1)" "unprognostic (1.75e-2)" "unprognostic (3.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.97e-2)" "unprognostic (1.86e-1)" "unprognostic (3.64e-2)" "unprognostic (9.61e-2)" "unprognostic (6.02e-2)" "unprognostic (1.02e-5)" "unprognostic (1.29e-2)" "unprognostic (7.75e-2)" "unprognostic (9.23e-3)" 4.2 11.1 4.9 0.3 6.5 1.3 2.0 9.0 8.1 5.1 0.0 0.2 0.1 1.2 2.8 0.6 0.4 0.3 2.2 6.9 1.3 3.0 0.0 0.4 0.3 0.0 1.4 3.6 1.0 0.4 0.0 0.4 0.0 1.6 0.3 0.4 1.0 1.3 8.3 1.7 0.2 0.9 0.0 0.1 0.1 1.1 2.8 0.6 0.3 4.7 0.0 0.3 0.3 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 2.7 0.4 0.5 1.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.9 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 4.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.0 0.9 4.9 6.5 9.0 8.1 6.9 1.3 0.0 1.4 0.0 0.0 2.8 1.4 0.6 0.0 0.0 3.3 0.0 12.0 0.6 0.0 0.0 3.3 3.2 2.2 1.3 2.8 0.0 3.7 0.0 0.0 0.0 0.1 1.9 0.0 0.5 0.4 2.1 1.1 0.0 0.0 52.3 1.5 0.0 11.0 0.0 1.6 0.0 33.9 0.0 0.0 4.1 0.0 48.8 0.0 0.0 4.3 18.5 2.1 49.7 4.7 21.4 1.0 6.6 0.0 1.0 29.7 2.6 0.7 0.0 16.1 0.0 1.4 0.0 0.9 0.0 0.4 26.3 4.1 4.5 0.4 1.1 0.0 11.6 0.0 1.1 6.4 0.0 0.6 SLN "MGC12301, MGC125854, MGC125855" ENSG00000170290 Sarcolipin O00631 11 107707378-107719693 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 8190.2;tongue: 3399.6" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 730.3;Muller glia cells: 462.5;Skeletal myocytes: 225.1" "Group enriched" "Detected in many" 5 "glioma: 21.6;head and neck cancer: 22.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.1;HSkMC: 2.5;Karpas-707: 1.2;PC-3: 1.1;SuSa: 2.5;U-2 OS: 1.1" CAB011628 Approved Microtubules NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Microtubules "CAB011628: AB_2195046" "unprognostic (6.85e-2)" "unprognostic (6.18e-8)" "unprognostic (2.60e-1)" "unprognostic (3.66e-2)" "unprognostic (2.40e-3)" "unprognostic (4.12e-3)" "unprognostic (5.28e-3)" "unprognostic (1.31e-2)" "unprognostic (2.76e-1)" "unprognostic (6.35e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.52e-9)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "unprognostic (5.09e-4)" "unprognostic (3.77e-2)" 5.1 8.3 2.8 0.0 3.4 0.0 2.1 3.9 7.8 0.2 1.3 4.7 0.3 0.2 0.8 149.2 0.7 0.3 975.1 2.4 1.4 2.6 0.7 6.4 0.2 1.5 2.3 0.6 1.8 0.2 0.7 1.3 2.3 37.0 0.1 60.7 59.4 0.3 8190.2 4.4 1.5 1.4 1.3 0.3 0.8 1.3 1.4 2.7 2.0 3399.6 0.9 0.4 1.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 3.4 3.9 7.8 2.4 1.4 1.5 2.3 2.3 1.3 1.4 2.0 0.0 0.0 0.0 0.0 0.0 1.0 1.2 0.0 0.0 2.4 0.0 0.0 730.3 0.0 0.0 0.0 2.1 1.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 10.5 0.0 0.0 0.3 0.4 1.9 42.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.3 0.0 0.0 0.0 0.0 1.1 8.8 0.0 1.0 0.0 0.0 0.0 462.5 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.2 0.0 0.4 0.0 19.9 0.0 225.1 40.5 0.1 0.0 0.0 1.4 5.7 1.0 0.0 0.0 0.1 SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1039.2;skin 1: 858.5" "Group enriched" "Detected in some" 16 "Squamous epithelial cells: 20.8;Suprabasal keratinocytes: 65.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 66.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.3;MCF7: 1.5;RT4: 1.1;T-47d: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" NA NA 7700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA050967: AB_2681293" "unprognostic (1.22e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (7.32e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-4)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" 0.9 0.6 0.1 0.0 0.0 0.0 11.3 0.7 0.5 105.0 0.0 0.3 0.0 0.2 0.0 1039.2 0.2 0.2 0.4 0.1 0.0 0.2 0.5 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 70.1 0.0 1.4 858.5 0.3 0.0 0.0 0.2 0.8 0.3 0.1 0.9 0.2 0.0 17.4 0.3 206.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.6 0.0 0.0 1.8 1.5 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.8 65.8 0.0 0.0 0.0 0.0 0.8 SMAD9 "MADH6, MADH9, SMAD8, SMAD8/9" ENSG00000120693 "SMAD family member 9" O15198 13 36844831-36920765 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 38.7" "Cell type enhanced" "Detected in many" "Astrocytes: 48.0;Enteroendocrine cells: 51.6;Glandular and luminal cells: 73.4;Hepatic stellate cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 12.9;HEK 293: 12.3;SH-SY5Y: 40.2" "Low region specificity" "Detected in all" "CAB009119, HPA031162" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "CAB009119: AB_2286517, HPA031162: AB_2673767" "unprognostic (2.88e-1)" "unprognostic (1.38e-1)" "unprognostic (9.68e-3)" "unprognostic (3.50e-3)" "prognostic favorable (5.99e-4)" "unprognostic (1.30e-1)" "unprognostic (1.34e-1)" "unprognostic (3.71e-3)" "unprognostic (4.23e-2)" "unprognostic (6.62e-2)" "unprognostic (4.07e-3)" "unprognostic (3.74e-2)" "unprognostic (9.70e-2)" "unprognostic (1.55e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.92e-4)" "unprognostic (2.47e-2)" 4.0 2.6 10.7 2.8 7.8 0.1 1.6 10.7 6.8 4.8 1.2 5.1 2.3 8.9 9.8 4.2 4.3 7.0 5.6 10.3 16.3 3.2 0.9 4.9 2.2 17.2 10.9 9.2 0.9 2.4 1.9 6.5 16.9 13.9 5.3 7.0 21.0 11.2 3.0 1.5 2.5 6.7 15.5 0.9 3.7 2.3 9.6 0.5 38.7 5.1 2.9 3.3 2.1 21.3 0.0 0.1 0.8 8.6 2.6 1.1 0.3 10.5 1.1 2.7 1.7 0.0 0.2 0.2 7.2 12.9 0.9 0.4 9.3 0.2 2.8 0.3 12.3 0.0 4.4 6.6 2.4 0.8 0.1 4.4 0.8 0.0 0.0 5.7 5.3 1.1 0.1 0.0 6.0 0.6 0.1 0.8 1.2 0.3 1.1 0.2 9.2 0.0 0.0 1.5 7.6 40.2 1.9 0.2 0.5 2.3 0.6 0.4 9.6 4.0 3.5 2.4 2.6 0.1 0.0 0.1 2.8 0.3 0.6 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 10.7 7.8 10.7 6.8 10.3 16.3 17.2 10.9 16.9 15.5 9.6 21.3 22.5 28.9 11.5 48.0 0.4 2.8 4.3 1.8 1.8 13.1 2.5 2.2 5.9 2.8 6.9 11.0 4.2 0.2 0.2 3.3 1.9 0.3 0.1 30.3 14.0 26.7 51.6 0.0 18.1 0.2 0.6 11.6 3.6 73.4 0.0 19.7 43.9 0.1 0.1 0.0 33.0 15.6 8.2 2.2 1.9 0.3 18.6 1.1 0.0 31.9 0.0 20.4 0.0 14.1 39.3 0.5 3.4 15.1 0.0 17.2 0.0 7.3 1.6 3.2 0.0 7.2 10.1 1.2 14.1 0.2 1.8 0.3 1.4 0.5 5.7 1.2 SMCO4 "C11orf75, FN5" ENSG00000166002 "Single-pass membrane protein with coiled-coil domains 4" Q9NRQ5 11 93478472-93543391 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 195.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 211.3;Paneth cells: 165.3;Proximal enterocytes: 200.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 113.7" "Low region specificity" "Detected in all" HPA041120 Uncertain NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA041120: AB_2677309" "unprognostic (7.45e-2)" "unprognostic (1.70e-3)" "unprognostic (2.54e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-1)" "unprognostic (6.47e-2)" "unprognostic (8.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.43e-1)" "unprognostic (5.51e-1)" "unprognostic (4.23e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (5.81e-7)" "unprognostic (1.61e-1)" "unprognostic (3.05e-1)" "unprognostic (1.55e-2)" "unprognostic (5.01e-2)" 21.0 70.4 8.9 30.6 8.2 7.3 23.0 8.2 12.6 17.0 17.3 35.3 45.9 18.9 13.9 23.1 27.9 16.8 53.5 10.2 22.9 66.3 135.1 35.8 31.4 11.9 14.7 25.3 60.0 5.8 48.0 11.4 11.2 55.2 25.7 3.4 195.8 11.5 17.0 24.3 37.6 15.2 11.1 61.8 50.1 43.4 32.4 17.5 71.7 5.9 22.9 12.4 22.8 12.8 8.3 15.3 23.9 5.5 8.0 10.6 15.4 25.2 7.5 10.8 19.9 26.6 33.0 24.6 29.0 22.1 16.8 5.0 24.1 3.5 7.3 68.6 22.2 5.9 32.4 58.0 7.4 24.4 26.1 15.0 13.2 5.0 3.8 13.6 16.7 81.5 13.8 113.7 3.3 13.9 24.4 50.2 25.0 62.6 23.9 42.8 12.0 11.2 21.5 19.8 4.2 18.5 19.6 26.3 2.1 30.2 10.4 33.7 10.9 9.7 40.6 33.4 20.8 4.6 0.7 19.7 7.6 40.9 4.9 40.2 263.5 6.9 4.1 316.4 18.4 25.0 26.9 8.0 150.3 26.9 3.7 3.2 61.4 32.0 296.3 155.5 11.7 91.5 8.9 8.2 8.2 12.6 10.2 22.9 11.9 14.7 11.2 11.1 32.4 12.8 26.0 25.6 18.4 0.3 11.5 32.8 33.4 17.4 6.2 2.1 62.0 50.5 36.7 70.1 17.2 49.7 0.0 6.6 27.7 105.1 211.3 43.2 123.5 14.3 2.9 24.9 44.9 6.1 4.8 70.2 9.0 19.0 27.5 16.1 2.5 21.3 15.7 103.9 140.4 3.3 10.6 116.4 6.1 91.3 80.3 146.8 12.8 87.7 30.2 13.1 123.3 6.4 11.3 0.5 4.4 31.1 165.3 10.5 15.0 92.8 200.0 64.8 9.6 1.3 6.6 4.2 14.1 11.2 46.6 16.6 21.3 4.8 15.0 6.4 58.7 47.3 SMIM1 Vel ENSG00000235169 "Small integral membrane protein 1 (Vel blood group)" B2RUZ4 1 3772749-3775982 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.3;testis: 42.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 84.1;Erythroid cells: 404.4;Granulosa cells: 81.5;Proximal tubular cells: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "eosinophil: 48.5" "Lineage enriched" "Detected in many" 12 "granulocytes: 48.5" "Group enriched" "Detected in many" 4 "HEL: 68.0;Hep G2: 32.5;K-562: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA069088 Enhanced NA NA 340000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA069088: AB_2686080" "unprognostic (9.50e-3)" "unprognostic (7.19e-4)" "unprognostic (5.40e-2)" "unprognostic (2.10e-2)" "unprognostic (2.50e-3)" "unprognostic (3.25e-1)" "unprognostic (2.63e-3)" "unprognostic (2.13e-2)" "unprognostic (2.31e-2)" "unprognostic (9.85e-2)" "unprognostic (2.90e-1)" "unprognostic (1.87e-1)" "unprognostic (2.25e-2)" "unprognostic (7.10e-2)" "unprognostic (2.91e-2)" "unprognostic (5.56e-2)" "unprognostic (1.32e-2)" 2.6 2.7 1.8 0.4 2.6 32.1 3.2 3.8 3.0 5.8 6.2 2.9 0.7 2.8 1.1 1.4 3.4 1.3 40.3 1.4 3.9 16.9 13.1 3.7 1.0 8.7 5.3 8.7 9.4 4.3 16.0 2.1 9.0 6.9 0.1 0.4 17.3 5.5 1.1 2.1 2.1 0.2 5.5 4.0 6.6 42.2 3.6 0.4 9.3 0.2 0.5 3.4 3.6 6.2 0.3 1.4 1.4 3.0 0.0 0.0 5.0 0.9 1.2 0.0 0.0 3.5 3.9 0.1 6.3 0.0 0.2 1.3 0.4 1.5 0.0 6.1 3.6 68.0 0.0 32.5 2.4 0.0 1.2 2.1 0.8 0.3 0.5 2.9 0.0 0.3 33.9 1.2 0.0 7.8 0.0 2.1 0.3 3.4 6.0 0.0 0.0 9.9 3.8 1.0 1.6 6.3 0.2 6.8 4.8 0.5 7.0 3.7 0.4 0.0 0.8 0.0 0.0 2.8 0.8 0.2 0.0 0.0 0.2 4.4 2.0 48.5 1.1 1.0 0.4 2.5 1.6 0.6 0.6 3.7 4.0 1.9 3.2 0.2 0.4 0.6 1.2 2.2 1.8 2.6 3.8 3.0 1.4 3.9 8.7 5.3 9.0 5.5 3.6 6.2 1.1 6.4 20.1 0.7 5.9 1.7 13.1 4.4 10.2 0.4 31.1 35.9 57.0 8.6 8.1 16.5 0.0 23.4 1.4 1.6 84.1 17.2 10.8 3.7 1.2 3.9 5.4 404.4 0.1 14.5 18.8 10.1 6.6 3.5 1.3 81.5 3.9 50.2 10.4 1.7 0.1 3.9 8.2 8.9 1.0 27.8 9.9 8.5 42.7 0.0 4.3 47.0 2.1 0.0 1.6 13.7 1.7 9.8 11.1 10.2 1.9 247.9 2.2 1.5 0.0 3.6 4.3 8.7 20.4 1.7 1.1 6.7 4.6 3.0 4.3 9.1 SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390440-6394998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 131.3;Late spermatids: 200.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 139.1;fHDF/TERT166: 144.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (6.99e-2)" "unprognostic (2.28e-3)" "prognostic unfavorable (7.72e-5)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (4.90e-2)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.47e-4)" "unprognostic (4.35e-2)" "prognostic favorable (4.57e-6)" "unprognostic (4.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" 21.8 36.5 38.8 13.9 44.7 7.3 20.1 45.1 43.0 21.2 33.9 25.3 16.8 20.9 14.4 20.6 14.6 21.5 55.8 39.1 43.0 73.7 95.3 31.3 14.6 42.7 42.6 17.9 32.8 34.2 41.9 21.6 43.3 29.4 14.9 8.5 29.0 20.0 37.9 37.9 23.8 17.6 40.9 21.1 25.4 14.0 47.5 17.8 34.0 29.4 11.0 23.6 21.0 46.8 16.4 13.1 10.1 26.5 139.1 72.2 17.1 60.4 95.0 27.7 33.0 22.0 11.9 4.7 27.4 144.0 59.3 7.4 8.4 12.7 13.0 21.0 9.6 5.1 19.5 6.0 62.3 3.7 37.4 96.0 23.4 25.9 17.7 100.9 61.6 1.7 9.1 30.5 58.9 17.0 0.1 6.5 3.9 23.2 22.3 1.2 5.5 7.0 23.9 6.2 17.0 9.7 27.6 19.5 38.5 12.9 7.3 7.0 53.9 103.0 10.9 59.1 15.4 37.6 44.0 3.5 93.7 10.8 47.1 1.9 2.5 3.4 6.4 2.1 5.0 1.5 5.5 5.0 1.3 3.1 10.0 10.1 2.5 6.6 0.6 1.7 4.7 3.2 38.8 44.7 45.1 43.0 39.1 43.0 42.7 42.6 43.3 40.9 47.5 46.8 14.1 25.6 14.4 10.7 12.2 7.9 22.8 15.3 6.8 12.6 13.7 9.0 37.7 24.3 12.8 25.8 25.0 38.8 11.5 131.3 11.7 53.4 50.0 6.2 13.0 18.6 23.8 9.9 5.8 38.2 14.4 31.4 15.8 21.0 10.8 9.4 26.7 88.5 34.1 20.2 5.5 20.3 24.4 15.5 6.2 200.7 11.5 15.8 55.2 4.7 7.8 16.4 36.0 6.6 15.5 24.7 83.1 13.5 23.1 26.0 51.7 75.1 2.4 5.2 0.0 8.9 17.1 1.4 3.1 7.5 8.0 34.3 23.3 10.2 18.0 15.4 SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.3;Distal enterocytes: 291.5;Paneth cells: 157.5;Proximal enterocytes: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cell line enhanced" "Detected in many" "ASC diff: 44.2;hTCEpi: 36.9;OE19: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 15.0 23.3 4.6 18.7 5.1 22.9 23.7 8.2 9.4 72.8 8.9 60.7 45.5 13.3 6.5 13.6 7.9 17.2 5.6 5.3 5.7 47.4 80.0 14.1 21.4 5.9 5.4 9.1 20.8 32.4 7.5 44.0 5.9 21.8 65.7 6.0 13.7 16.6 39.8 64.5 77.3 8.5 5.7 27.0 30.5 2.9 5.4 5.1 9.1 55.8 16.2 35.5 30.9 7.7 0.3 2.6 6.1 2.8 44.2 19.9 19.5 10.4 27.8 3.1 6.6 3.3 2.7 0.0 1.4 6.6 8.2 4.9 1.7 5.3 2.6 0.0 5.4 2.5 9.8 9.0 28.3 0.0 0.1 24.4 36.9 3.0 5.3 12.0 5.5 0.0 3.8 0.0 12.7 9.3 0.0 0.2 1.1 58.8 8.0 0.0 10.8 0.4 15.1 4.2 4.4 0.1 1.5 18.5 27.9 3.9 3.1 1.4 11.0 5.9 3.5 0.6 6.8 0.0 0.0 0.0 8.7 4.9 13.7 80.9 4.0 1.1 0.0 4.3 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 7.5 0.0 0.0 1.4 4.6 5.1 8.2 9.4 5.3 5.7 5.9 5.4 5.9 5.7 5.4 7.7 11.8 3.2 17.8 5.2 2.4 53.7 24.5 13.7 15.9 3.0 12.2 6.6 4.0 25.8 9.7 5.5 4.2 156.3 0.4 291.5 56.7 24.6 0.2 4.2 12.6 7.1 48.7 5.7 7.4 25.7 40.4 46.3 34.7 5.2 10.1 0.8 18.9 77.8 62.7 3.3 10.5 61.7 59.0 126.3 10.0 1.2 15.5 33.4 35.6 11.2 9.9 11.5 2.1 11.1 11.0 19.5 157.5 14.3 0.9 16.7 383.1 129.3 7.5 6.2 13.1 12.8 9.9 1.1 3.7 15.5 76.0 115.1 2.0 11.4 38.9 16.6 SMU1 "BWD, FLJ10805, fSAP57, SMU-1" ENSG00000122692 "SMU1 DNA replication regulator and spliceosomal factor" Q2TAY7 9 33041765-33076674 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019708 Supported Approved Vesicles NA NA 25000 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019708: AB_1857300" "unprognostic (2.20e-2)" "prognostic favorable (2.66e-4)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (1.80e-2)" "unprognostic (8.44e-2)" "unprognostic (2.59e-3)" "unprognostic (5.06e-2)" "unprognostic (3.04e-2)" "prognostic favorable (1.25e-4)" "unprognostic (4.98e-3)" "unprognostic (3.15e-1)" "prognostic favorable (1.67e-5)" "unprognostic (1.09e-2)" "unprognostic (7.04e-2)" "unprognostic (8.71e-2)" "unprognostic (5.96e-2)" 11.5 11.3 11.2 10.6 13.0 16.0 11.9 13.9 12.1 11.4 8.6 10.9 8.6 13.1 11.8 10.6 11.4 8.6 10.3 10.7 11.5 11.2 12.9 10.0 12.8 12.4 11.9 14.7 8.2 15.8 8.1 8.4 12.4 11.9 10.9 12.6 9.3 11.5 14.4 12.8 9.4 13.2 12.6 12.1 9.1 8.5 11.7 14.1 11.2 13.0 15.2 11.5 9.9 16.6 26.3 20.4 24.0 20.9 25.4 19.3 18.7 20.1 18.1 26.9 26.5 20.8 10.7 33.0 14.4 25.1 14.6 15.7 31.1 24.1 29.7 38.1 14.9 24.8 33.4 24.5 22.1 43.5 22.4 20.4 27.0 24.9 17.6 20.1 22.9 22.7 23.4 20.5 22.7 12.1 34.2 46.3 33.1 19.6 21.4 28.8 19.9 17.9 20.5 19.4 20.3 17.7 27.2 19.4 13.1 18.6 18.7 15.7 24.6 17.2 19.1 25.2 23.8 9.1 18.1 38.0 19.2 20.2 12.5 23.4 13.9 11.5 12.4 15.4 13.3 12.9 14.0 11.6 15.8 11.7 13.9 14.3 8.1 12.4 17.9 20.0 12.6 10.8 11.2 13.0 13.9 12.1 10.7 11.5 12.4 11.9 12.4 12.6 11.7 16.6 45.5 25.6 31.4 17.9 48.0 53.7 45.7 41.0 43.3 29.5 23.8 22.4 30.6 30.0 39.9 20.2 37.5 34.9 72.7 19.1 21.5 32.3 29.6 41.6 42.8 38.2 28.1 24.4 23.4 24.3 36.3 37.7 17.9 47.3 39.2 32.1 21.4 29.4 30.8 23.5 25.3 19.5 44.7 29.2 40.8 8.7 32.3 40.2 23.2 14.0 39.7 34.8 32.0 21.6 28.3 27.9 20.1 25.9 28.3 33.3 18.1 31.7 44.1 39.3 19.7 53.9 44.7 41.4 30.5 36.3 57.5 57.7 43.7 37.0 23.5 35.5 SNCA "NACP, PARK1, PARK4, PD1" ENSG00000145335 "Synuclein alpha" P37840 4 89700345-89838315 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Alzheimer disease, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 273.6;brain: 128.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 1225.0;Excitatory neurons: 251.5;Melanocytes: 352.2;Oligodendrocytes: 195.4" "Cancer enriched" "Detected in many" 8 "melanoma: 37.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 102.9" "Group enriched" "Detected in all" 4 "dendritic cells: 102.9;granulocytes: 51.5;monocytes: 66.9" "Cell line enhanced" "Detected in many" "HEL: 221.5;HUVEC TERT2: 269.8;RT4: 137.3;SK-MEL-30: 271.6;TIME: 311.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005459, CAB010877" Enhanced "Intracellular and membrane" NA NA 28000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010877: AB_261518, HPA005459: AB_2667324" "unprognostic (4.80e-2)" "unprognostic (1.52e-1)" "unprognostic (8.13e-2)" "unprognostic (1.05e-3)" "unprognostic (2.65e-2)" "unprognostic (1.54e-2)" "unprognostic (1.78e-2)" "unprognostic (3.44e-2)" "unprognostic (1.73e-2)" "unprognostic (3.85e-3)" "unprognostic (1.01e-3)" "unprognostic (2.09e-2)" "unprognostic (1.57e-1)" "unprognostic (2.51e-3)" "unprognostic (1.68e-1)" "unprognostic (3.93e-4)" "unprognostic (7.48e-3)" 16.0 9.9 91.5 10.0 112.2 273.6 7.8 47.2 128.2 26.1 16.1 28.5 3.3 34.3 3.4 8.5 11.2 5.4 20.9 115.2 69.1 12.4 2.9 16.6 2.2 97.5 88.3 29.3 2.2 1.1 28.7 28.3 89.9 17.3 6.9 20.3 15.9 9.7 1.2 16.4 8.6 33.3 36.0 15.2 6.4 3.2 76.2 5.3 10.2 8.5 4.8 9.3 23.2 107.0 0.5 1.0 40.1 0.0 0.7 0.0 0.6 0.4 44.5 1.6 3.0 0.0 0.0 0.2 12.0 0.0 0.0 9.3 53.6 97.7 1.5 0.0 22.6 221.5 115.4 0.5 84.2 0.0 1.4 2.1 38.2 0.0 109.5 117.3 269.8 2.2 2.0 0.6 0.2 0.0 2.1 0.3 10.6 0.2 4.8 0.0 15.8 0.0 0.3 137.3 23.2 15.6 0.2 0.3 271.6 29.0 0.0 0.4 311.4 1.3 8.0 0.1 0.8 0.2 0.2 0.1 8.8 0.2 87.4 51.5 66.9 0.1 0.3 27.7 0.1 4.2 1.9 0.3 84.6 1.7 1.0 0.5 11.1 17.3 8.2 102.9 0.0 63.7 91.5 112.2 47.2 128.2 115.2 69.1 97.5 88.3 89.9 36.0 76.2 107.0 1.8 0.0 0.6 40.1 2.6 76.6 16.3 173.4 101.3 10.4 0.9 14.4 13.4 0.0 21.5 11.0 0.0 10.1 10.1 0.1 1.9 0.0 0.6 0.3 1.1 19.4 1.8 1225.0 251.5 0.2 1.9 32.7 0.0 0.3 0.0 23.9 7.5 0.8 62.3 10.1 53.8 0.0 44.7 17.2 64.2 1.5 2.1 100.7 352.2 76.8 24.4 19.4 4.1 95.5 195.4 0.2 0.0 0.0 0.5 11.3 0.0 2.0 6.6 7.4 13.1 0.5 5.3 19.6 16.9 4.5 22.6 3.4 3.8 43.6 0.0 3.4 SNW1 "Bx42, FUN20, NCoA-62, Prp45, PRPF45, SKIIP, SKIP, SKIP1" ENSG00000100603 "SNW domain containing 1" Q13573 14 77717599-77761207 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 300.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002457, CAB009931, HPA017370" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB009931: AB_2302187, HPA002457: AB_1080047, HPA017370: AB_1857339" "unprognostic (1.24e-3)" "unprognostic (2.02e-1)" "unprognostic (2.40e-1)" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (4.27e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.07e-1)" "unprognostic (8.09e-3)" "unprognostic (2.88e-2)" "unprognostic (3.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (2.47e-1)" "unprognostic (1.55e-1)" "unprognostic (4.45e-3)" "unprognostic (1.22e-2)" 47.1 33.3 27.6 33.6 29.5 91.2 42.7 30.6 35.9 39.2 29.1 38.4 32.6 39.0 28.4 38.4 38.3 26.7 39.5 27.0 29.0 38.7 33.6 37.1 46.2 29.5 28.6 41.4 38.6 31.3 30.3 33.0 29.8 32.2 32.1 43.3 34.0 21.9 64.8 50.7 38.5 30.9 28.6 44.6 36.6 48.5 28.4 49.0 33.9 35.9 41.9 38.8 38.0 32.9 91.0 66.6 67.0 70.8 54.5 60.6 76.5 61.3 54.6 66.8 61.2 66.0 81.0 88.3 54.5 46.1 50.8 88.2 81.8 58.9 90.3 71.1 63.5 71.8 59.1 66.7 77.7 50.5 81.0 46.8 76.1 60.0 82.8 71.5 65.8 83.7 103.9 64.7 51.9 93.1 90.7 85.4 74.2 103.1 87.8 97.3 85.5 61.7 61.4 82.6 71.2 76.5 84.7 73.6 87.3 68.1 106.6 95.5 69.9 71.6 81.7 64.9 73.9 62.9 95.5 98.7 65.5 79.8 80.9 94.5 71.0 95.6 57.5 76.9 65.5 59.2 64.5 65.9 72.6 67.0 67.6 63.9 67.8 94.5 92.1 43.2 94.5 76.1 27.6 29.5 30.6 35.9 27.0 29.0 29.5 28.6 29.8 28.6 28.4 32.9 86.5 93.0 49.3 13.1 64.2 56.5 80.4 89.1 33.6 56.0 40.1 50.0 49.9 47.1 77.9 53.3 35.5 79.4 75.4 38.0 76.3 79.0 43.5 97.2 81.3 69.9 43.6 85.0 17.9 70.1 100.1 64.9 26.5 80.5 92.3 61.5 55.6 33.7 76.4 38.7 18.6 50.8 54.9 53.6 52.0 24.0 77.9 70.7 39.2 30.0 95.6 66.7 65.9 15.6 31.9 71.3 43.8 74.1 46.3 48.9 48.8 57.3 88.1 72.2 65.7 60.9 89.5 300.5 140.7 39.7 54.3 109.0 76.8 54.4 47.9 70.9 SOCS2 "CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2" ENSG00000120833 "Suppressor of cytokine signaling 2" O14508 12 93569814-93583487 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 203.6;Hepatic stellate cells: 134.6" "Cancer enhanced" "Detected in all" "prostate cancer: 16.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 177.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 177.8" "Cell line enhanced" "Detected in many" "CACO-2: 192.0;K-562: 145.6;REH: 336.6;THP-1: 142.3" "Low region specificity" "Detected in all" CAB010356 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "CAB010356: AB_2239660" "unprognostic (4.16e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" "prognostic favorable (1.09e-6)" "unprognostic (1.07e-1)" "unprognostic (1.49e-1)" "unprognostic (5.35e-3)" "prognostic favorable (8.17e-7)" "unprognostic (1.71e-1)" "unprognostic (1.67e-3)" "unprognostic (2.35e-2)" "unprognostic (1.51e-1)" "unprognostic (7.40e-2)" "unprognostic (9.09e-2)" 71.5 34.8 7.8 10.4 12.0 11.5 68.0 7.2 8.5 92.6 23.1 40.5 11.7 91.8 42.0 16.5 42.4 20.7 28.6 9.8 9.2 42.8 59.1 61.9 9.2 8.1 10.9 19.2 13.8 64.5 55.3 36.5 8.8 81.4 17.0 4.8 9.5 45.4 9.5 9.4 17.3 89.5 6.6 8.5 30.8 8.7 10.4 21.4 32.8 6.1 9.1 32.1 50.4 7.8 3.5 4.9 16.8 15.2 9.1 16.6 19.8 20.8 77.0 15.2 6.6 192.0 7.8 1.0 0.7 19.3 4.1 39.8 88.6 5.9 17.3 69.0 2.5 13.9 1.2 2.7 13.8 4.2 28.5 28.3 4.9 16.7 22.7 1.6 2.1 8.7 145.6 3.1 2.4 1.8 0.8 6.8 47.4 3.2 7.4 336.6 0.3 3.6 4.1 7.4 28.8 34.2 7.3 11.5 57.5 16.0 0.2 142.3 2.3 47.2 0.7 0.3 11.7 2.0 1.1 1.4 0.9 12.0 28.8 177.8 0.2 7.7 25.4 0.5 34.2 0.4 31.2 23.3 0.2 4.3 30.6 18.4 1.1 26.8 0.4 2.0 19.8 14.4 7.8 12.0 7.2 8.5 9.8 9.2 8.1 10.9 8.8 6.6 10.4 7.8 203.6 9.6 78.7 1.0 1.4 18.0 46.0 3.2 1.2 8.2 30.5 16.9 6.5 0.0 24.3 22.0 4.2 36.3 15.5 20.8 62.6 13.7 9.8 10.5 94.9 100.5 8.3 33.2 10.9 37.4 6.7 34.6 7.1 20.2 24.1 9.9 134.6 11.6 14.2 69.0 12.3 13.3 4.1 8.9 20.7 20.3 91.6 6.0 17.8 8.4 108.4 1.5 18.6 1.0 1.3 8.8 21.2 101.2 6.4 95.2 20.0 27.5 5.4 1.2 78.9 15.8 32.9 9.9 10.5 1.8 10.5 35.0 15.7 12.7 15.7 30.1 SOD3 EC-SOD ENSG00000109610 "Superoxide dismutase 3" P08294 4 24789912-24800842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Antioxidant, Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 436.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 498.5;Leydig cells: 424.1;Peritubular cells: 365.6;Smooth muscle cells: 428.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.2;BJ: 38.1;PC-3: 55.1;RPTEC TERT1: 231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042110 Supported "Secreted to blood" NA NA 50400000 510000000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "HPA042110: AB_2677850" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (8.80e-2)" "unprognostic (3.32e-2)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (4.98e-2)" "unprognostic (3.68e-1)" "unprognostic (2.39e-1)" "unprognostic (3.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-2)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.45e-2)" 221.4 20.4 14.3 26.1 20.9 0.0 134.2 15.8 23.8 226.5 436.1 122.7 18.2 151.6 10.4 62.1 177.6 22.4 150.1 47.1 14.1 124.1 16.5 155.0 10.6 22.9 23.4 59.7 86.7 2.6 19.8 39.8 17.5 131.3 13.4 1.9 70.9 23.4 22.0 91.9 65.2 37.1 16.4 24.8 102.1 74.1 19.0 5.8 176.6 22.9 7.0 178.3 170.4 13.6 0.0 0.0 0.0 0.0 66.2 17.3 2.0 38.1 16.7 2.3 1.4 0.5 0.0 0.0 11.8 8.0 0.1 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.0 16.8 0.0 15.8 0.0 17.9 0.1 0.0 1.1 0.0 0.0 0.1 0.3 1.1 8.0 0.0 55.1 0.0 0.0 0.6 231.3 0.8 0.2 0.2 0.0 1.2 0.0 2.1 32.8 0.0 0.0 8.7 1.0 1.6 0.4 0.1 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 20.9 15.8 23.8 47.1 14.1 22.9 23.4 17.5 16.4 19.0 13.6 46.1 12.8 18.1 7.2 1.0 90.8 65.5 0.6 10.2 0.4 21.7 22.1 23.0 144.4 7.6 90.1 0.0 211.4 1.8 25.6 15.6 63.6 18.7 81.9 45.8 21.0 34.6 0.0 0.1 1.8 17.0 498.5 5.1 80.3 0.0 0.1 15.4 0.2 17.3 0.0 0.1 51.9 0.0 0.3 115.5 33.9 424.1 3.2 80.0 3.7 0.0 20.7 0.0 0.5 0.7 3.5 89.3 365.6 1.1 80.4 0.0 142.7 0.1 1.4 197.2 6.5 428.9 73.2 4.4 6.1 70.3 190.0 7.6 6.1 51.8 9.6 SORL1 "C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1" ENSG00000137642 "Sortilin related receptor 1" Q92673 11 121452314-121633763 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Transport" Receptor "Alzheimer disease, Amyloidosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 79.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 387.8;Excitatory neurons: 247.4;Microglial cells: 404.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 125.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 125.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 142.8;Daudi: 68.7;OE19: 93.5;RT4: 102.1;U-698: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011500, HPA031321" Uncertain "Secreted to blood" NA NA 79000 "Cluster 5: Granulocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB011500: AB_443414, HPA031321: AB_2673826" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.08e-2)" "unprognostic (9.53e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-3)" "unprognostic (1.74e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.80e-7)" "unprognostic (2.48e-1)" "unprognostic (1.87e-1)" "unprognostic (5.07e-2)" "unprognostic (1.21e-2)" 7.0 6.1 29.1 24.4 39.1 47.4 13.9 49.5 35.5 44.4 0.0 17.3 11.6 5.4 8.9 5.4 40.1 7.3 2.4 33.8 39.7 19.0 58.2 10.4 21.1 40.3 46.8 9.0 8.0 10.4 16.8 2.3 47.0 20.8 16.9 20.3 21.8 25.4 1.7 3.4 18.1 4.5 45.3 21.8 10.3 5.1 38.8 17.0 13.5 4.0 23.0 15.7 6.6 79.1 1.3 8.1 7.3 1.1 0.0 0.0 7.4 0.4 2.4 0.3 0.0 11.9 142.8 68.7 8.5 1.8 10.5 47.4 9.1 7.0 0.1 0.0 2.6 0.0 10.3 16.8 0.1 29.6 0.1 0.0 7.6 0.0 25.8 4.0 0.0 8.7 0.0 0.7 0.0 9.7 7.1 15.3 8.8 93.5 10.8 7.7 0.4 1.6 15.8 102.1 5.1 1.5 15.2 21.5 0.0 16.0 21.0 9.5 0.3 0.1 4.9 1.0 0.0 0.0 0.0 139.8 0.1 38.6 0.4 44.3 15.9 59.1 22.1 6.9 29.3 1.9 24.6 20.0 6.6 5.1 23.1 20.8 125.7 20.9 9.4 16.4 19.3 21.2 29.1 39.1 49.5 35.5 33.8 39.7 40.3 46.8 47.0 45.3 38.8 79.1 1.6 6.4 23.3 160.9 20.7 4.5 42.3 23.3 18.2 68.8 44.5 22.0 12.3 18.6 36.8 79.1 387.8 0.4 130.1 132.1 0.0 10.3 1.2 21.6 2.9 10.3 6.1 8.8 247.4 0.7 0.7 5.8 14.3 24.7 12.0 20.6 34.6 114.5 39.1 50.5 80.1 54.6 40.7 62.4 16.9 5.0 77.9 67.0 3.6 404.7 97.5 28.0 146.2 74.9 86.0 6.4 81.1 57.9 28.6 36.1 168.6 1.0 15.6 31.2 0.0 19.5 10.3 2.9 18.8 20.8 2.4 0.4 60.2 32.7 42.2 33.4 SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 111.3;stomach 1: 60.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 68.5;Distal tubular cells: 29.4;Gastric mucus-secreting cells: 76.5;Horizontal cells: 30.3;Ionocytes: 128.1;Melanocytes: 32.0" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;EFO-21: 12.7;HEL: 4.8;NTERA-2: 4.9;RPTEC TERT1: 23.5" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" 0.2 0.5 1.3 0.9 2.7 0.1 17.9 1.7 3.4 2.6 111.3 10.9 11.6 4.7 0.3 3.7 5.0 0.3 3.1 3.7 0.3 22.3 0.0 39.2 0.1 0.7 0.9 1.1 0.6 0.6 2.4 0.0 0.1 1.8 15.0 3.0 15.6 3.5 0.1 16.8 8.6 1.1 0.2 0.1 60.4 1.9 2.2 0.1 8.6 0.9 3.9 1.4 3.5 1.8 0.0 0.0 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 12.7 0.0 0.0 0.3 0.4 0.0 0.0 0.1 2.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.3 0.1 0.0 0.1 0.7 0.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.7 1.7 3.4 3.7 0.3 0.7 0.9 0.1 0.2 2.2 1.8 0.4 0.0 0.0 0.0 0.2 5.6 4.3 2.1 9.1 0.6 68.5 17.8 3.8 0.0 2.0 14.7 0.0 0.0 0.4 1.2 29.4 0.0 19.7 1.0 0.1 2.9 2.4 0.0 0.0 0.0 0.0 3.9 76.5 1.5 0.0 0.0 0.4 0.1 0.0 30.3 0.0 0.2 128.1 0.0 1.2 13.0 7.2 0.4 32.0 0.0 0.0 14.2 0.0 0.0 0.0 0.4 2.2 2.6 0.4 1.1 0.0 21.8 0.0 0.7 0.0 0.1 0.3 3.4 1.2 14.1 7.2 0.0 0.9 0.0 2.3 1.5 SPAAR "LINC00961, SPAR" ENSG00000235387 "Small regulatory polypeptide of amino acid response" A0A1B0GVQ0 9 35909490-35937153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.4;breast: 10.8" "Cell type enriched" "Detected in some" 7 "Adipocytes: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HUVEC TERT2: 34.0;TIME: 40.1" "Not detected" "Not detected" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.17e-1)" "unprognostic (2.19e-2)" "unprognostic (1.91e-2)" "unprognostic (7.00e-3)" "unprognostic (4.23e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.40e-3)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.72e-2)" "unprognostic (7.12e-3)" "unprognostic (1.67e-2)" "unprognostic (3.04e-1)" "unprognostic (1.27e-1)" "unprognostic (3.22e-1)" 12.4 1.2 2.9 0.6 2.5 0.0 10.8 2.2 3.3 0.7 1.1 1.2 0.3 1.2 0.1 0.5 1.2 0.6 8.9 2.3 2.2 4.2 0.8 3.2 0.4 3.0 2.6 0.7 0.5 0.5 0.6 4.7 3.1 1.0 0.4 1.4 0.7 0.5 3.1 0.9 0.9 0.6 2.3 0.7 0.9 7.5 3.3 0.2 1.9 1.8 0.0 1.5 0.8 2.4 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.6 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.4 0.1 0.2 0.0 0.0 34.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 40.1 0.0 0.8 2.7 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.5 2.2 3.3 2.3 2.2 3.0 2.6 3.1 2.3 3.3 2.4 42.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 5.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 SPAG16 "DKFZp666P1710, FLJ22724, PF20, WDR29" ENSG00000144451 "Sperm associated antigen 16" Q8N0X2 2 213284379-214410501 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 243.1;Inhibitory neurons: 273.7;Respiratory ciliated cells: 330.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037542 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA037542: AB_10672353" "unprognostic (4.20e-2)" "unprognostic (2.73e-1)" "unprognostic (2.67e-1)" "unprognostic (9.79e-2)" "unprognostic (1.83e-1)" "unprognostic (1.30e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (4.90e-4)" "prognostic favorable (3.82e-4)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-1)" "unprognostic (1.17e-1)" 16.3 16.8 36.6 6.4 37.4 2.4 20.8 35.1 45.9 21.0 39.0 16.5 18.8 18.2 31.6 26.1 46.5 22.0 22.2 34.2 37.8 30.4 18.8 10.8 11.5 38.8 39.6 25.8 15.5 24.4 29.7 9.8 37.8 22.1 17.2 21.5 15.7 20.5 10.3 24.9 10.9 12.1 40.9 8.0 26.1 46.3 38.4 13.0 26.4 10.8 13.8 18.9 19.4 40.6 26.8 9.9 29.4 0.0 19.3 35.0 0.2 14.3 17.1 18.3 19.3 20.8 28.8 11.1 16.7 16.0 29.3 18.5 13.4 17.4 38.6 0.0 10.5 5.8 28.0 24.6 21.9 6.3 0.1 30.1 23.5 16.3 9.5 25.0 7.6 11.6 18.8 12.3 18.4 0.0 21.4 0.1 16.3 0.0 8.7 22.6 30.9 0.5 29.4 25.8 21.4 25.1 16.3 15.1 21.3 24.2 70.3 2.7 7.8 17.2 9.2 9.3 15.1 20.0 9.7 0.4 28.6 0.0 8.0 2.0 0.3 0.9 8.1 1.3 11.7 9.3 9.1 10.4 3.1 8.5 12.0 10.4 0.5 15.4 0.9 5.1 9.4 3.4 36.6 37.4 35.1 45.9 34.2 37.8 38.8 39.6 37.8 40.9 38.4 40.6 17.7 16.0 19.5 89.5 10.7 42.3 46.6 82.8 22.8 47.6 38.0 45.6 67.5 74.4 73.6 40.5 95.9 50.6 7.5 17.1 76.3 44.0 243.1 207.0 31.3 18.5 38.2 9.0 205.9 24.9 20.8 30.8 32.1 30.3 10.1 34.0 12.8 16.9 11.7 40.4 273.7 37.8 101.7 4.6 9.6 86.2 41.3 5.9 23.2 42.2 29.2 82.7 8.2 92.0 74.9 27.3 18.8 44.8 9.4 25.4 9.4 94.9 330.0 69.0 13.1 30.8 36.1 167.9 31.0 64.6 56.4 23.5 12.9 55.3 39.8 53.8 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPARCL1 MAST9 ENSG00000152583 "SPARC like 1" Q14515 4 87473335-87531061 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 4430.9;Endothelial cells: 2372.1;Peritubular cells: 2523.5;Sertoli cells: 4674.1;Skeletal myocytes: 2379.0;Smooth muscle cells: 2781.9" "Cancer enhanced" "Detected in all" "glioma: 528.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 24.9;SuSa: 31.4;U-266/70: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026225 Enhanced "Secreted in other tissues" NA NA 630000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB026225: " "unprognostic (1.02e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.63e-3)" "unprognostic (1.73e-2)" "unprognostic (3.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (2.45e-3)" "unprognostic (1.76e-2)" "unprognostic (5.72e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (3.33e-4)" 755.6 129.5 664.6 124.5 810.9 0.5 532.1 612.4 1058.4 732.7 580.4 624.3 125.1 1244.5 443.8 308.1 754.5 487.9 600.2 744.6 723.5 72.5 25.0 481.1 99.1 655.7 730.9 286.8 91.8 128.0 197.8 315.4 663.4 584.2 187.5 95.2 228.3 999.2 244.8 130.2 280.1 1191.2 774.7 157.9 347.7 97.5 694.8 103.2 369.9 594.7 100.0 488.0 466.4 681.2 0.7 0.0 24.9 0.3 0.2 0.1 2.6 0.1 0.1 0.0 0.0 0.0 0.1 0.4 1.8 0.0 0.0 1.4 2.4 0.0 0.0 1.7 0.0 0.3 1.1 0.4 1.1 0.3 1.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.3 0.0 0.5 0.2 3.5 0.6 0.0 0.0 0.3 0.4 1.2 0.0 0.1 0.8 1.6 0.1 0.2 0.1 31.4 0.4 0.5 0.0 0.2 0.3 1.5 0.2 9.1 1.4 0.6 3.4 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 664.6 810.9 612.4 1058.4 744.6 723.5 655.7 730.9 663.4 774.7 694.8 681.2 4430.9 12.8 56.4 1155.7 6.2 46.3 187.2 0.6 59.7 10.7 24.4 251.6 334.2 4.3 43.3 7.3 2.1 2.2 8.6 0.0 13.7 0.8 11.8 34.9 935.8 2372.1 0.0 32.0 382.3 0.4 3.2 1413.1 6.1 46.7 7.6 1.4 899.5 9.1 9.2 3.3 450.1 0.0 0.0 5.3 55.2 47.0 659.5 31.6 56.9 261.4 0.0 179.4 0.0 210.6 53.8 0.1 0.0 2523.5 25.2 50.4 0.0 24.6 7.4 34.4 4674.1 2379.0 2781.9 5.7 7.9 56.8 39.9 2.5 26.9 38.8 0.0 124.2 SPATA18 FLJ32906 ENSG00000163071 "Spermatogenesis associated 18" Q8TC71 4 52051304-52097299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 68.3;testis: 28.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2341.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 31.5;BEWO: 24.4;BJ hTERT+: 15.9;HSkMC: 29.3;hTCEpi: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036854, HPA036855" Enhanced Supported Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA036854: AB_10670927, HPA036855: AB_2675352" "unprognostic (6.54e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.32e-5)" "unprognostic (1.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.27e-2)" "unprognostic (4.49e-2)" "unprognostic (1.76e-1)" "unprognostic (2.73e-1)" "unprognostic (3.13e-1)" "unprognostic (3.13e-2)" "prognostic favorable (3.73e-9)" "unprognostic (4.38e-1)" "unprognostic (1.39e-1)" "unprognostic (1.01e-2)" "unprognostic (4.00e-2)" 2.1 5.0 2.4 0.7 2.2 0.0 6.3 1.3 1.0 10.7 15.6 4.1 2.1 4.2 2.0 4.6 68.3 6.7 1.8 2.5 2.7 5.3 5.4 8.0 0.3 6.8 8.3 1.8 2.0 4.5 4.9 1.9 5.5 4.2 5.6 0.1 10.1 5.6 0.8 6.6 2.2 3.1 6.0 0.6 4.9 28.8 2.6 3.2 1.2 1.3 0.9 2.8 3.4 3.8 0.0 3.8 1.8 0.0 12.7 31.5 24.4 9.3 15.9 0.6 0.7 0.0 1.5 0.0 0.0 12.3 0.2 0.3 0.1 7.1 0.3 0.0 1.1 0.0 0.0 8.0 11.2 0.0 0.0 29.3 28.7 1.0 4.5 5.1 6.9 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.9 2.0 1.0 0.0 0.0 9.7 0.0 0.2 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.2 1.3 1.0 2.5 2.7 6.8 8.3 5.5 6.0 2.6 3.8 0.3 9.6 3.0 0.3 0.0 5.2 8.5 9.4 8.6 0.0 6.0 6.7 2.2 8.6 15.1 0.0 0.0 1.7 0.3 1.8 1.9 1.2 561.1 124.6 1.8 1.2 1.8 0.0 1.7 2.6 1.8 4.3 11.2 4.7 2.5 1.9 1.4 3.4 0.3 0.0 0.5 1.6 6.1 0.6 1.6 2341.5 10.8 1.1 0.0 2.8 0.1 0.0 0.0 0.5 0.1 2.0 2.7 10.9 0.0 5.1 1.9 7.4 141.4 0.0 0.0 1.8 3.9 13.9 7.1 7.1 7.5 0.8 0.2 2.5 4.3 6.8 SPATA3 TSARG1 ENSG00000173699 "Spermatogenesis associated 3" Q8NHX4 2 230990324-231025055 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 179 "testis: 176.7" "Cell type enriched" "Detected in some" 6 "Late spermatids: 5258.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA018254 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA018254: AB_1857419" "unprognostic (6.94e-3)" "unprognostic (6.98e-2)" "unprognostic (9.62e-2)" 0.0 0.0 0.4 0.0 0.5 0.1 0.1 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 176.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.4 0.5 0.5 0.5 0.6 0.4 0.2 0.9 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 783.7 0.0 0.0 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5258.5 22.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 23.9 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7" "Group enriched" "Detected in many" 6 "Hofbauer cells: 432.9;Kupffer cells: 411.9;Langerhans cells: 537.6;Macrophages: 453.3;monocytes: 357.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 179.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 179.7" "Cell line enhanced" "Detected in some" "HEL: 90.1;HL-60: 159.7;HMC-1: 282.2;NB-4: 267.8;THP-1: 206.7;U-698: 85.3;U-937: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" 36.5 19.7 12.0 107.3 13.1 335.1 17.7 14.3 19.4 7.9 15.8 15.6 21.5 7.3 2.1 9.1 19.1 21.3 13.5 11.7 16.4 10.6 15.6 101.0 65.0 31.2 20.9 5.2 7.8 3.1 7.6 28.0 24.7 10.3 10.2 1.0 14.6 6.1 5.0 13.8 29.3 21.9 19.8 172.7 17.0 3.7 26.2 15.7 8.8 8.3 32.0 29.9 7.6 30.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.2 0.1 0.0 0.0 72.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 0.0 159.7 282.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.7 0.0 0.0 0.2 267.8 0.2 0.0 0.0 48.7 0.2 47.5 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 206.7 0.3 0.0 0.5 0.5 0.1 0.1 0.3 85.3 0.3 117.5 0.1 14.1 19.2 179.7 0.0 27.4 0.0 3.9 0.0 0.0 16.4 2.4 0.0 0.0 83.8 0.0 34.7 0.9 0.0 7.3 12.0 13.1 14.3 19.4 11.7 16.4 31.2 20.9 24.7 19.8 26.2 30.3 2.1 3.2 1.1 10.4 72.6 10.5 0.5 0.0 1.2 1.3 2.1 5.0 2.9 4.3 0.6 5.5 0.0 2.3 6.3 0.5 19.6 0.1 7.5 0.1 0.3 5.5 4.2 39.7 3.1 0.4 3.1 2.6 1.1 0.3 33.7 0.2 7.9 3.2 432.9 0.0 3.3 0.3 0.0 411.9 537.6 27.5 1.8 453.3 10.6 36.5 357.5 7.0 8.2 3.5 1.5 0.0 0.1 0.0 21.8 0.4 0.2 2.3 0.7 1.7 13.1 1.5 1.4 5.1 9.3 0.8 9.9 4.2 4.8 1.1 0.4 0.5 SPINK7 "ECG2, ECRG2" ENSG00000145879 "Serine peptidase inhibitor Kazal type 7" P58062 5 148312419-148315922 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 256.8;esophagus: 620.4;vagina: 614.0" "Cell type enriched" "Detected in some" 7 "Squamous epithelial cells: 49.2" "Group enriched" "Detected in many" 6 "cervical cancer: 4.5;head and neck cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036294 Enhanced "Secreted in other tissues" NA NA 230000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA036294: AB_10671243" "unprognostic (2.82e-1)" "unprognostic (8.99e-3)" "unprognostic (8.52e-3)" "unprognostic (1.81e-1)" "unprognostic (1.12e-2)" "unprognostic (3.37e-2)" "unprognostic (9.10e-2)" "unprognostic (1.49e-1)" "unprognostic (6.86e-2)" "unprognostic (7.24e-2)" "unprognostic (4.22e-2)" 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.3 256.8 0.1 0.1 0.0 0.1 0.1 620.4 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.7 0.0 0.3 0.1 0.0 0.0 140.1 0.0 0.2 9.3 0.1 0.1 0.1 0.1 4.2 0.1 0.2 4.7 0.1 0.1 115.9 0.6 614.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.3 0.1 0.2 0.1 0.2 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 0.0 0.0 0.0 0.0 0.0 4.5 SPN "CD43, GPL115, LSN" ENSG00000197471 Sialophorin P16150 16 29662979-29670876 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 71.8;lung: 28.3;lymphoid tissue: 51.1" "Cell type enhanced" "Detected in many" "dendritic cells: 131.6;Erythroid cells: 125.9;Macrophages: 65.8;monocytes: 66.4;NK-cells: 352.2;Plasma cells: 60.3;T-cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 218.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 278.8;HL-60: 281.5;HMC-1: 158.3;MOLT-4: 122.2;REH: 98.4;THP-1: 164.1;U-937: 205.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002666, HPA055244" Enhanced Approved "Plasma membrane" NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB002666: , HPA055244: AB_2682756" "prognostic favorable (1.40e-4)" "unprognostic (1.63e-3)" "unprognostic (3.14e-2)" "prognostic favorable (3.08e-5)" "unprognostic (2.68e-2)" "unprognostic (2.49e-3)" "unprognostic (4.02e-2)" "unprognostic (4.17e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.70e-1)" "unprognostic (4.67e-2)" "unprognostic (2.68e-1)" "unprognostic (2.61e-2)" "unprognostic (4.52e-2)" "unprognostic (4.14e-2)" "unprognostic (5.85e-2)" "unprognostic (4.72e-2)" 4.0 0.6 0.8 14.4 1.0 71.8 1.8 1.1 0.9 1.4 0.2 3.9 5.5 1.6 1.1 3.0 2.0 4.3 2.8 0.9 1.4 0.8 2.6 28.3 26.3 3.5 1.3 0.6 1.0 0.6 0.2 0.9 2.5 1.3 5.3 0.3 2.3 1.1 0.8 2.8 6.3 2.3 1.8 19.0 5.0 0.4 2.5 51.1 0.8 0.3 23.0 4.2 0.5 4.1 0.2 0.2 0.1 0.3 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.9 0.1 0.6 1.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 278.8 0.2 2.0 0.0 281.5 158.3 0.0 0.0 0.1 0.0 0.1 0.0 68.0 96.1 76.9 0.5 0.2 122.2 70.1 0.1 0.0 0.0 98.4 1.1 2.2 0.0 0.0 0.2 0.1 0.2 0.3 0.1 0.3 0.1 164.1 0.4 0.0 0.2 0.2 0.2 0.3 5.8 40.7 0.3 205.4 0.3 13.6 23.2 14.6 96.3 96.3 51.4 3.7 38.5 65.5 34.0 1.1 26.3 47.6 3.6 69.4 218.0 27.2 34.7 52.1 0.8 1.0 1.1 0.9 0.9 1.4 3.5 1.3 2.5 1.8 2.5 4.1 1.2 9.6 16.9 0.0 10.8 2.2 0.9 0.0 0.0 0.6 1.0 0.8 5.3 1.5 2.5 1.8 0.0 0.2 131.6 0.1 0.0 0.1 0.1 0.5 0.6 3.0 0.0 125.9 0.0 0.0 0.4 3.0 5.1 0.7 43.7 0.8 4.6 1.5 27.0 1.7 0.0 0.3 0.0 28.8 30.3 0.0 0.0 65.8 1.8 1.9 66.4 0.5 352.2 1.5 0.0 0.0 0.1 0.0 60.3 0.5 0.1 0.6 1.5 1.9 0.0 0.8 1.0 0.2 0.6 0.1 2.0 0.3 94.8 0.1 0.2 0.6 SPNS2 SLC62A2 ENSG00000183018 "Sphingolipid transporter 2" Q8IVW8 17 4498881-4539035 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.0" "Cell type enhanced" "Detected in many" "Adipocytes: 32.7;Endothelial cells: 34.5;Microglial cells: 37.5;Oligodendrocytes: 97.8;Urothelial cells: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 31.0;RPTEC TERT1: 161.7;SK-BR-3: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068717 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA068717: AB_2686021" "unprognostic (3.03e-2)" "unprognostic (4.76e-2)" "unprognostic (8.08e-2)" "unprognostic (3.53e-2)" "unprognostic (2.78e-1)" "unprognostic (6.30e-3)" "unprognostic (1.10e-3)" "unprognostic (2.33e-1)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.99e-2)" "unprognostic (2.98e-2)" "unprognostic (4.48e-2)" "unprognostic (2.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.19e-2)" "unprognostic (6.89e-2)" 17.3 2.6 13.1 5.2 14.0 7.9 14.7 13.1 18.2 14.6 0.1 6.5 12.2 8.6 0.6 51.0 7.8 12.1 10.7 14.1 12.1 28.6 3.8 28.3 4.9 26.4 16.2 1.8 10.0 1.1 2.1 7.9 28.9 5.3 2.1 0.6 16.5 2.0 4.4 24.8 10.8 4.8 13.9 11.4 21.0 1.3 15.5 1.7 8.5 3.9 13.3 6.6 22.6 25.1 9.7 1.2 0.0 0.2 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.5 8.1 0.5 11.8 0.0 0.1 0.5 0.0 0.7 0.0 0.1 0.2 0.6 0.2 0.0 0.1 3.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 4.7 0.0 0.0 0.0 3.8 0.2 17.0 0.1 17.6 0.3 0.8 0.0 0.3 161.7 0.5 5.4 0.2 0.0 76.7 0.0 5.1 2.7 7.5 0.2 0.2 0.7 0.3 0.1 0.3 0.3 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.1 14.0 13.1 18.2 14.1 12.1 26.4 16.2 28.9 13.9 15.5 25.1 32.7 6.4 10.6 1.6 0.2 1.8 0.4 2.1 0.0 1.2 4.3 3.6 1.2 22.8 16.2 22.0 0.0 1.3 0.2 2.8 1.9 16.7 0.2 0.5 1.0 34.5 0.0 3.2 23.4 3.0 30.5 1.7 26.0 2.8 0.0 0.0 12.5 6.7 1.1 6.7 26.2 12.7 2.0 0.3 1.6 0.2 0.6 1.9 1.8 37.5 0.0 0.4 0.0 3.5 97.8 18.6 0.0 0.4 1.2 11.7 1.9 24.3 16.9 1.1 0.0 1.4 3.1 0.6 0.5 0.6 2.4 1.9 1.6 0.1 1.1 39.8 SPTBN2 SCA5 ENSG00000173898 "Spectrin beta, non-erythrocytic 2" O15020 11 66682497-66729226 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6;skin 1: 85.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;Cone photoreceptor cells: 104.3;Early spermatids: 30.9;Late spermatids: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 45.6;NTERA-2: 49.1;SCLC-21H: 49.9;SK-BR-3: 52.3;T-47d: 67.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009844, HPA039293, HPA043529" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Vesicles "CAB009844: AB_2194521, HPA039293: AB_2676430, HPA043529: AB_2678531" "unprognostic (9.34e-2)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (3.41e-3)" "unprognostic (4.91e-1)" "unprognostic (6.05e-3)" "unprognostic (4.45e-2)" "unprognostic (1.38e-2)" "unprognostic (7.25e-2)" "unprognostic (1.67e-2)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.64e-1)" "unprognostic (1.05e-3)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" "unprognostic (3.99e-2)" "unprognostic (1.00e-3)" 1.3 14.4 26.8 1.0 32.6 2.3 7.7 29.7 73.6 14.3 0.0 0.9 0.9 1.7 1.2 39.8 3.7 1.7 1.4 38.8 0.3 37.5 23.3 1.1 0.2 4.8 0.9 0.9 16.7 13.1 16.4 0.4 3.2 12.4 0.7 14.7 29.6 4.7 0.5 85.5 1.0 1.1 0.0 0.9 2.9 52.8 4.6 1.0 0.3 0.1 6.7 1.6 16.5 24.2 20.5 7.4 3.4 0.3 0.1 0.0 0.6 0.3 0.1 0.1 0.0 4.8 28.2 0.2 3.7 0.0 0.7 16.9 25.2 2.4 0.0 0.1 10.4 0.1 45.6 3.0 0.8 7.3 0.6 0.2 11.5 0.0 7.4 4.2 6.3 5.2 7.3 0.1 0.1 35.2 6.3 3.5 49.1 28.7 21.1 23.8 2.8 14.7 9.6 4.8 49.9 29.4 14.0 52.3 3.2 2.7 67.2 2.4 1.4 0.1 8.6 1.3 11.5 0.7 3.0 14.7 0.1 0.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 26.8 32.6 29.7 73.6 38.8 0.3 4.8 0.9 3.2 0.0 4.6 24.2 0.7 3.2 1.1 4.9 0.3 3.7 2.7 3.2 2.8 11.0 4.7 4.6 1.8 1.5 4.6 86.5 104.3 0.9 0.0 0.6 0.0 2.6 30.9 3.6 1.8 1.1 3.0 7.2 29.3 10.0 0.3 0.8 1.5 3.6 0.0 1.4 1.4 24.7 0.1 0.0 20.7 1.6 0.0 0.3 0.7 77.6 1.8 0.1 0.0 2.8 0.6 1.6 0.0 7.5 4.6 7.5 0.2 1.5 0.8 3.2 0.2 1.3 3.5 21.3 0.0 0.2 0.5 8.5 9.4 14.6 12.5 0.3 0.2 0.1 0.8 1.7 SPTBN5 "BSPECV, HUBSPECV, HUSPECV" ENSG00000137877 "Spectrin beta, non-erythrocytic 5" Q9NRC6 15 41848146-41894053 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 8.8;retina: 26.9" "Group enriched" "Detected in many" 22 "Cone photoreceptor cells: 210.6;Rod photoreceptor cells: 211.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.7;SCLC-21H: 5.1;TIME: 13.6;WM-115: 4.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "spinal cord: 3.6" HPA055283 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA055283: " "unprognostic (5.46e-2)" "unprognostic (2.49e-1)" "unprognostic (3.28e-2)" "unprognostic (2.01e-1)" "unprognostic (2.26e-2)" "unprognostic (5.84e-3)" "unprognostic (1.12e-1)" "unprognostic (6.84e-3)" "unprognostic (6.40e-3)" "unprognostic (2.25e-1)" "unprognostic (2.96e-2)" "unprognostic (6.92e-2)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.28e-1)" "unprognostic (1.37e-2)" "unprognostic (1.11e-2)" 1.0 0.3 0.4 0.7 1.3 0.4 1.1 8.8 1.4 0.6 0.1 0.5 0.3 0.4 0.8 1.7 0.5 0.9 2.0 0.6 0.1 1.7 1.6 1.2 0.6 0.8 0.3 0.6 1.1 0.5 1.9 0.2 1.0 1.6 0.2 26.9 2.7 0.3 0.4 1.7 0.5 0.2 0.1 0.5 1.0 0.8 0.1 0.0 2.1 0.4 0.1 2.6 0.7 0.8 0.2 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.6 0.0 0.8 0.0 1.5 0.4 0.0 0.2 0.0 0.8 0.1 0.0 1.6 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.3 0.0 0.3 1.4 5.1 0.1 0.2 0.4 0.1 0.4 0.8 0.0 13.6 0.0 1.3 0.3 1.7 1.5 2.3 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 8.8 1.4 0.6 0.1 0.8 0.3 1.0 0.1 0.1 0.8 1.9 0.0 2.4 2.9 0.2 0.8 0.9 0.4 1.2 7.9 1.8 2.0 4.0 0.0 1.5 0.0 210.6 0.1 0.8 0.7 0.0 0.5 1.1 1.1 0.3 3.7 0.0 0.0 2.3 0.2 0.3 0.6 2.0 3.8 1.3 1.0 0.4 0.5 2.0 3.3 0.5 0.5 0.0 0.0 0.6 0.9 0.0 1.0 1.8 0.0 0.8 9.6 1.0 6.0 0.5 1.0 1.4 0.0 0.9 0.2 0.2 0.6 0.8 211.8 0.0 0.2 0.3 0.5 0.5 3.9 1.3 0.0 0.5 0.2 0.6 1.0 SPTLC3 "C20orf38, FLJ11112, hLCB2b, LCB2B, SPTLC2L" ENSG00000172296 "Serine palmitoyltransferase long chain base subunit 3" Q9NUV7 20 13008972-13169103 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.4;Early spermatids: 27.9;Glandular and luminal cells: 47.4;Microglial cells: 35.6;Syncytiotrophoblasts: 46.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 33.3;RPTEC TERT1: 43.7;U-2197: 30.4;U-87 MG: 57.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA044247, HPA048079" Enhanced Approved Microtubules NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" Microtubules "HPA044247: AB_2678872, HPA048079: AB_2680252" "unprognostic (6.81e-2)" "unprognostic (7.76e-2)" "unprognostic (4.46e-2)" "unprognostic (1.25e-3)" "unprognostic (5.43e-2)" "unprognostic (2.12e-1)" "unprognostic (5.70e-2)" "unprognostic (7.99e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (5.08e-2)" "prognostic favorable (4.51e-7)" "unprognostic (2.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.18e-1)" 4.6 4.3 1.4 1.4 1.4 0.6 8.3 1.2 1.3 7.4 8.5 6.1 15.7 4.7 16.8 5.9 6.7 10.9 6.4 1.5 2.7 18.2 20.0 7.8 1.3 2.4 2.1 7.1 5.6 11.0 2.7 20.9 2.4 5.9 7.4 2.8 6.7 3.6 0.4 25.6 16.2 3.9 1.8 2.9 4.5 6.4 3.8 5.0 24.4 2.0 1.7 5.7 5.1 2.5 1.5 2.4 1.8 0.0 14.1 20.2 11.4 0.0 3.2 2.1 8.2 18.6 9.3 0.0 1.2 0.6 18.2 25.0 0.0 7.0 3.0 0.0 0.1 0.0 5.6 26.4 1.3 0.0 0.2 11.5 21.4 8.4 2.8 7.7 1.4 4.4 0.0 33.3 23.7 0.5 0.1 0.0 0.1 2.2 2.9 2.3 4.2 15.1 43.7 18.2 0.0 0.3 0.2 2.3 0.1 3.1 18.6 0.5 3.3 9.2 3.1 30.4 2.2 0.2 0.0 0.0 57.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.4 1.4 1.2 1.3 1.5 2.7 2.4 2.1 2.4 1.8 3.8 2.5 3.6 6.4 22.3 5.2 0.1 2.4 5.3 2.3 4.6 0.1 5.4 5.0 17.9 4.3 4.9 9.2 0.0 28.4 1.0 3.4 7.9 3.0 27.9 18.7 5.2 4.6 0.0 2.1 0.5 4.4 13.0 5.4 4.6 47.4 1.3 5.6 1.8 20.7 2.8 0.0 0.9 5.7 6.1 2.6 0.4 11.6 3.7 2.4 0.0 35.6 0.0 12.3 3.1 0.0 0.1 3.2 6.7 2.6 0.1 2.3 10.9 18.6 3.5 0.4 0.0 6.1 0.8 1.2 0.1 4.9 2.3 46.1 1.2 2.9 7.3 2.6 SPX "C12orf39, MGC10946, NPQ, spexin" ENSG00000134548 "Spexin hormone" Q9BT56 12 21526296-21541249 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 111.4" "Group enriched" "Detected in some" 4 "Distal tubular cells: 86.1;Proximal tubular cells: 202.2" "Cancer enriched" "Detected in many" 5 "renal cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 17.5;HBEC3-KT: 8.9;hTERT-HME1: 12.4;SuSa: 14.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 17.1;hippocampal formation: 17.9;olfactory bulb: 7.5;pons: 8.0" "Secreted to blood" NA NA 2650000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.78e-2)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (1.81e-2)" "unprognostic (2.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (5.89e-2)" "unprognostic (1.21e-2)" "unprognostic (1.95e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.37e-3)" "unprognostic (9.78e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" 111.4 0.1 8.7 0.1 9.2 0.4 4.1 8.6 24.2 0.0 7.2 0.1 0.0 1.3 0.6 0.2 0.2 0.1 2.8 8.1 11.5 26.4 2.3 0.6 0.2 8.6 13.9 0.0 20.7 0.4 0.0 17.7 26.6 0.0 0.0 1.7 6.9 0.5 2.0 0.0 0.3 0.1 8.0 0.4 0.5 0.2 9.6 3.0 20.2 8.8 0.1 0.0 0.0 9.9 0.0 0.5 0.8 0.0 3.0 1.2 0.0 0.0 0.1 0.1 1.2 17.5 0.0 0.7 0.3 0.0 0.3 0.0 0.0 8.9 1.6 0.0 0.0 4.7 0.0 0.1 1.8 0.0 0.0 5.7 0.9 0.3 12.4 0.2 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.0 1.1 0.0 0.7 0.0 2.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 1.7 14.6 0.0 0.2 0.3 0.0 5.3 0.0 0.4 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.7 9.2 8.6 24.2 8.1 11.5 8.6 13.9 26.6 8.0 9.6 9.9 1.4 0.0 0.0 1.3 1.3 0.0 0.1 0.0 0.0 3.0 0.7 0.9 28.9 0.0 0.0 25.8 0.0 0.0 0.1 0.0 86.1 0.4 0.0 0.5 0.3 0.6 0.0 0.0 0.0 19.1 0.0 1.7 0.0 2.5 0.0 0.0 0.7 0.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 13.7 0.0 0.0 1.2 4.9 4.1 0.0 0.1 2.5 0.0 0.0 0.0 0.1 0.0 202.2 0.0 0.5 0.0 2.4 0.9 0.0 1.8 0.0 0.0 0.4 1.0 0.1 0.0 0.1 SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633427-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 29.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.2;Hepatocytes: 103.4;Ionocytes: 52.9;Squamous epithelial cells: 139.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA051402: AB_2681470" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavorable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" 1.5 2.0 4.7 1.9 5.3 2.2 11.0 7.4 8.8 3.9 0.1 2.4 4.1 1.7 3.0 11.0 1.7 1.7 1.0 5.5 3.2 4.6 29.0 1.9 2.3 6.0 3.3 2.5 2.3 1.4 1.1 1.0 6.3 1.5 2.3 3.8 2.7 1.1 1.3 13.6 4.1 1.6 1.8 1.4 2.5 1.5 6.9 1.6 1.3 0.7 4.1 1.1 6.6 8.3 5.2 6.1 8.0 6.7 7.6 7.3 3.5 5.7 4.5 5.7 3.5 6.0 5.3 7.1 8.1 8.7 9.1 9.8 6.6 4.0 6.0 4.3 2.6 2.2 15.3 3.7 3.4 3.3 1.8 5.4 11.3 4.1 3.2 4.2 2.9 2.7 3.7 6.2 7.5 7.1 1.4 3.6 4.5 4.1 4.7 5.1 5.8 2.0 7.6 5.4 14.0 6.4 18.2 7.6 5.8 6.1 2.6 0.9 5.8 8.6 3.4 14.2 7.6 2.3 3.6 2.6 7.2 3.6 8.0 3.5 1.3 0.5 0.3 1.0 0.2 0.5 0.3 0.5 1.6 0.6 0.2 0.3 0.7 0.5 1.1 0.7 0.4 0.5 4.7 5.3 7.4 8.8 5.5 3.2 6.0 3.3 6.3 1.8 6.9 8.3 3.7 3.2 2.7 7.8 11.9 18.5 6.7 19.0 67.2 5.0 14.5 9.1 2.6 11.5 12.8 5.5 4.2 0.9 5.0 8.3 7.9 9.8 8.1 2.6 4.3 3.2 2.4 4.4 15.5 4.7 7.4 4.7 16.3 3.2 1.3 6.0 4.6 103.4 13.0 6.7 14.9 7.2 52.9 19.4 11.6 2.6 3.4 11.6 7.2 6.5 50.7 5.1 10.3 9.0 7.6 6.7 10.4 7.9 7.2 9.4 24.9 23.4 10.4 3.8 0.0 3.7 6.1 3.4 4.4 139.2 30.4 0.8 5.9 5.2 12.0 10.2 SRGAP2B SRGAP2P2 ENSG00000196369 "SLIT-ROBO Rho GTPase activating protein 2B" P0DMP2 1 144887265-145095528 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.7" "Cell type enriched" "Detected in many" 4 "Microglial cells: 239.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 3.6;granulocytes: 3.9;monocytes: 7.9" "Low cell line specificity" "Detected in all" HPA078079 Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" Cytosol "HPA078079: " "unprognostic (1.13e-2)" "unprognostic (2.76e-1)" "unprognostic (1.48e-3)" "unprognostic (3.52e-3)" "unprognostic (1.66e-2)" "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (4.60e-2)" "unprognostic (3.13e-1)" "unprognostic (2.89e-2)" "unprognostic (7.27e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-5)" "unprognostic (3.12e-1)" "unprognostic (5.43e-1)" "unprognostic (8.54e-2)" "unprognostic (2.38e-1)" 9.3 10.5 9.9 6.8 9.2 7.7 6.1 48.7 10.3 6.3 3.7 4.7 2.8 6.2 4.2 5.7 6.7 5.7 5.1 10.3 10.5 8.0 4.2 8.6 5.6 15.4 14.4 8.6 3.6 13.1 3.0 10.8 19.4 3.7 2.8 3.7 3.3 4.6 8.9 18.9 3.5 7.1 14.9 12.4 2.9 3.5 12.4 6.4 4.3 5.8 3.7 5.0 6.4 17.1 13.4 28.5 60.3 12.5 28.3 24.3 19.0 14.6 12.8 12.2 14.0 8.7 24.1 6.7 19.1 8.7 21.7 22.8 15.6 8.5 15.0 6.3 15.8 9.8 20.6 12.1 19.8 8.8 12.5 17.3 12.6 30.1 26.4 18.4 24.8 5.7 5.3 23.1 6.7 15.1 3.8 10.3 11.2 6.7 10.2 10.3 12.9 11.6 10.5 5.8 7.5 9.5 19.3 6.9 31.6 14.9 14.4 22.1 45.3 26.1 26.7 23.3 17.1 9.6 12.7 4.1 9.5 11.6 37.7 1.2 3.8 0.5 0.6 5.4 0.5 0.9 1.0 1.2 2.7 0.9 0.6 0.7 3.9 0.4 7.9 3.6 1.1 0.9 9.9 9.2 48.7 10.3 10.3 10.5 15.4 14.4 19.4 14.9 12.4 17.1 37.3 25.6 7.7 5.5 14.0 0.0 3.5 0.0 6.8 17.6 3.1 3.4 3.3 5.7 2.5 9.2 2.1 4.7 20.3 0.5 0.0 6.8 1.1 13.8 14.0 35.1 2.4 29.3 37.5 3.0 21.5 15.3 3.1 6.0 1.3 3.3 54.3 4.3 12.9 0.0 55.6 2.0 0.0 58.7 0.0 2.7 15.2 40.1 0.0 239.8 38.4 8.1 16.5 24.6 9.5 6.0 0.2 9.8 8.4 4.8 0.8 1.2 8.0 2.9 6.6 16.9 12.3 4.5 6.9 19.9 0.0 2.9 6.9 8.6 1.8 4.2 SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63540810-63547504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 1.6" "Cell type enriched" "Detected in single" 4 "Gastric mucus-secreting cells: 3.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.3;MCF7: 3.0;OE19: 4.4;RT4: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: AB_10609403, CAB044669: AB_10608235, HPA073987: AB_2686650" "unprognostic (2.26e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.62e-1)" "unprognostic (5.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.73e-3)" "unprognostic (2.58e-3)" "unprognostic (4.75e-2)" "unprognostic (4.97e-2)" "unprognostic (2.54e-3)" 0.0 0.0 0.1 0.2 0.1 0.1 0.4 0.6 0.2 0.0 0.0 0.7 0.2 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.8 0.0 0.0 0.4 0.2 0.0 0.1 0.9 1.6 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 1.3 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.1 0.0 4.4 0.4 0.0 0.1 0.0 0.0 6.0 0.4 0.5 0.1 1.2 0.2 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SRP68 ENSG00000167881 "Signal recognition particle 68" Q9UHB9 17 76038775-76072517 "Plasma proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 314.6" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 162.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "medulla oblongata: 314.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023303, HPA055617" Approved Supported Cytosol NA NA 23000 "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA023303: AB_1857477, HPA055617: AB_2682863" "unprognostic (1.25e-1)" "unprognostic (8.97e-2)" "unprognostic (3.47e-2)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.18e-4)" "prognostic unfavorable (4.28e-5)" "unprognostic (3.31e-2)" "unprognostic (8.31e-2)" "unprognostic (1.62e-2)" "unprognostic (1.11e-1)" "unprognostic (4.10e-2)" "unprognostic (4.42e-2)" "unprognostic (8.73e-2)" "unprognostic (4.75e-2)" "prognostic favorable (2.65e-4)" "unprognostic (4.02e-3)" 37.5 34.6 23.7 24.8 25.2 21.9 36.3 25.5 76.6 39.4 24.6 47.2 21.3 39.7 35.1 49.8 37.4 17.3 42.8 34.8 27.7 31.6 37.0 34.0 29.0 314.6 25.1 39.8 65.7 37.7 37.7 33.1 49.6 30.6 27.4 28.0 38.5 26.1 103.1 43.7 32.2 34.5 30.5 31.5 41.5 22.2 25.9 30.8 32.8 47.0 36.7 41.9 37.9 26.4 98.0 89.8 51.0 54.9 71.5 57.2 94.3 72.4 50.7 80.7 62.9 75.5 45.5 81.6 36.8 70.5 69.2 66.2 98.2 74.2 119.2 34.3 118.1 72.6 63.4 102.8 86.3 83.9 54.7 48.5 81.3 70.7 61.1 60.0 95.1 47.4 109.0 70.9 67.2 60.1 84.6 43.5 50.3 81.2 91.0 70.1 137.1 79.9 59.2 80.6 63.2 64.9 61.9 103.8 81.8 85.2 91.5 76.4 62.3 89.2 70.7 42.7 99.4 70.5 34.7 87.1 64.0 62.2 66.4 7.6 28.6 37.3 24.5 26.3 26.4 30.5 34.8 37.9 34.3 25.3 39.2 29.4 4.3 45.4 27.1 27.1 34.6 19.4 23.7 25.2 25.5 76.6 34.8 27.7 314.6 25.1 49.6 30.5 25.9 26.4 20.9 28.9 22.9 12.1 27.9 31.4 49.3 30.2 22.2 24.2 18.2 19.2 27.2 28.6 25.9 12.9 37.5 86.9 21.2 18.3 37.2 43.6 15.0 24.3 26.1 28.1 14.4 41.3 11.1 41.4 63.2 26.8 16.8 28.5 17.1 25.6 21.8 23.2 37.9 37.0 10.8 22.8 20.3 18.5 17.4 20.0 24.2 17.8 24.9 11.2 31.8 36.8 29.9 7.1 11.5 39.0 15.8 28.2 37.9 46.5 20.7 30.4 23.7 26.7 0.0 28.5 31.7 47.2 24.4 26.6 31.7 162.3 25.2 30.2 24.1 48.9 SST SMST ENSG00000157005 Somatostatin P61278 3 187668912-187670394 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 449.5;intestine: 386.6;pancreas: 479.4;stomach 1: 418.0" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 1404.1;Intestinal goblet cells: 460.2" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 1039.3" "Region enhanced" "Detected in all" "hypothalamus: 449.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 22.4;U-2 OS: 44.7;U-251 MG: 7.6;U-698: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000075, HPA019472, CAB034105" Enhanced Supported "Secreted to blood" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB000075: AB_2688022, CAB034105: AB_2271061, HPA019472: AB_1857360" "unprognostic (2.44e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.12e-3)" "unprognostic (1.54e-2)" "unprognostic (4.69e-1)" "unprognostic (3.31e-2)" "unprognostic (8.16e-3)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (8.47e-2)" "unprognostic (4.19e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" 5.5 43.0 59.9 4.6 52.1 4.2 0.5 1.3 67.8 0.6 2.5 31.8 386.6 0.7 0.1 1.6 0.4 1.1 1.3 30.6 449.5 6.2 0.3 0.3 1.5 96.9 48.1 2.4 479.4 0.0 9.3 0.1 50.3 1.3 23.8 6.3 0.1 21.6 0.1 8.9 133.3 2.8 137.8 0.2 418.0 0.2 117.2 1.1 1.0 0.0 0.0 7.3 1.8 18.7 0.0 0.0 0.8 0.1 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.5 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 44.7 0.4 7.6 0.0 2.9 11.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.9 52.1 1.3 67.8 30.6 449.5 96.9 48.1 50.3 137.8 117.2 18.7 0.0 0.0 0.0 9.1 0.5 0.0 0.0 3.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 5.5 0.0 0.1 0.0 4.3 0.0 0.0 0.3 0.3 0.5 0.1 1404.1 0.0 1.7 0.0 0.2 0.7 0.0 4.2 0.0 0.0 0.0 0.0 0.3 0.0 146.2 460.2 215.7 0.0 0.0 0.1 0.0 0.0 0.0 9.4 3.6 0.0 0.0 3.0 9.1 0.0 0.6 0.0 0.0 0.0 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.9 13.8 0.2 ST6GAL1 SIAT1 ENSG00000073849 "ST6 beta-galactoside alpha-2,6-sialyltransferase 1" P15907 3 186930325-187078553 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 495.9;lymphoid tissue: 148.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 237.3;Hepatic stellate cells: 258.5;Hepatocytes: 608.7;Microglial cells: 602.4" "Cancer enhanced" "Detected in all" "liver cancer: 70.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 250.6;U-266/70: 628.0;U-266/84: 887.9;U-698: 334.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015018, CAB016122" Supported "Secreted to blood" NA NA 15000000 3300000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB015018: AB_629203, CAB016122: AB_627178" "unprognostic (5.85e-3)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (2.64e-1)" "unprognostic (2.44e-2)" "unprognostic (1.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (3.99e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" "unprognostic (7.30e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-2)" 24.5 12.5 27.0 50.2 26.2 15.2 32.5 29.8 24.8 61.4 33.3 38.1 13.9 16.1 5.9 13.5 27.0 17.8 36.0 25.8 33.9 60.0 495.9 30.1 101.7 44.0 37.5 10.1 8.1 45.5 9.8 18.5 50.3 48.8 45.4 2.6 39.3 14.6 12.8 8.3 29.1 18.9 44.1 67.5 28.8 3.5 39.2 66.6 64.8 20.2 148.1 28.0 8.9 48.3 4.3 5.0 20.6 17.1 1.1 0.0 36.3 1.6 3.0 1.4 2.0 1.9 2.0 250.6 19.5 0.1 8.8 10.1 132.7 15.4 1.6 11.3 7.4 10.1 0.8 119.0 1.3 22.8 75.0 1.7 28.3 0.0 11.5 19.9 77.5 24.2 52.2 20.3 5.2 8.7 17.0 14.7 49.9 11.3 7.6 38.2 0.4 8.1 9.9 0.5 36.4 4.1 1.5 26.6 64.6 29.1 38.9 16.8 32.6 0.2 3.3 0.6 2.1 628.0 887.9 334.0 0.5 45.4 84.7 22.6 8.9 3.6 46.9 16.2 42.9 87.9 51.3 39.7 14.2 83.3 80.4 58.4 4.2 26.9 29.3 11.9 43.8 58.7 27.0 26.2 29.8 24.8 25.8 33.9 44.0 37.5 50.3 44.1 39.2 48.3 34.6 44.8 27.4 13.4 110.0 4.0 13.8 68.0 4.6 0.3 5.1 4.1 26.2 75.8 55.9 237.3 0.0 0.3 26.3 20.7 0.0 17.1 0.5 8.9 5.0 56.0 94.1 24.8 47.2 0.9 3.5 3.7 7.7 16.1 10.8 7.3 258.5 608.7 20.3 0.0 31.5 10.9 34.6 61.3 16.4 1.1 0.3 18.2 7.2 602.4 17.2 0.1 26.8 145.3 2.8 6.0 17.8 0.7 124.3 103.6 0.6 0.5 39.8 1.1 0.0 2.2 6.8 0.0 0.5 0.8 1.6 0.7 28.4 0.3 37.3 39.0 ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 912.5;Oligodendrocytes: 698.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 35.8;HUVEC TERT2: 45.9;SK-MEL-30: 62.3;TIME: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" 8.8 1.4 5.8 1.8 13.3 3.1 6.4 14.3 8.4 1.9 10.4 2.0 0.7 5.9 0.5 1.9 2.7 2.5 4.4 6.9 9.0 8.7 2.0 5.2 2.0 15.2 10.6 2.3 0.9 4.4 2.1 3.1 17.2 1.1 2.4 3.9 1.1 1.6 1.6 0.8 1.4 4.5 13.3 1.4 1.5 0.3 11.3 0.9 13.3 6.5 0.7 2.6 1.6 21.0 0.2 0.0 35.8 0.0 0.6 0.0 0.0 0.0 4.2 0.6 0.4 11.9 0.1 0.6 2.4 0.3 2.3 0.1 0.0 0.4 0.3 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.0 0.0 1.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 2.9 0.0 1.8 1.7 0.0 0.0 0.0 2.7 8.8 0.0 0.0 62.3 8.3 0.0 0.2 20.6 0.3 2.8 0.1 3.3 0.0 0.0 0.0 0.0 8.4 5.5 0.0 6.3 2.8 0.0 2.2 0.0 2.6 0.3 0.5 2.3 3.8 1.3 1.4 3.9 0.3 4.3 0.0 0.0 1.9 5.8 13.3 14.3 8.4 6.9 9.0 15.2 10.6 17.2 13.3 11.3 21.0 59.8 3.2 1.5 174.3 5.6 0.3 0.2 0.0 0.6 3.2 0.6 1.0 1.2 0.0 0.0 3.7 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.1 4.5 23.2 0.0 0.4 107.0 0.0 0.1 2.5 3.6 0.1 0.0 0.8 66.0 0.8 1.1 0.0 101.4 0.5 0.0 9.8 0.7 0.8 0.0 3.7 5.4 912.5 3.0 12.3 1.0 23.1 698.3 0.2 3.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.3 0.2 0.7 0.1 0.4 0.1 2.0 6.9 0.3 0.1 ST7L "FAM4B, FLJ20284, ST7R, STLR" ENSG00000007341 "Suppression of tumorigenicity 7 like" Q8TDW4 1 112523514-112620825 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 36.0" "Cell type enhanced" "Detected in all" "Early spermatids: 189.7;Late spermatids: 301.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042324, HPA075418" Uncertain Approved Centrosome NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Centrosome "HPA042324: AB_10794273, HPA075418: AB_2686749" "unprognostic (2.99e-2)" "unprognostic (1.07e-2)" "prognostic favorable (8.34e-5)" "prognostic unfavorable (8.96e-4)" "unprognostic (3.30e-2)" "unprognostic (1.32e-1)" "unprognostic (3.84e-6)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.16e-4)" "prognostic favorable (3.04e-5)" "unprognostic (2.98e-2)" "unprognostic (6.91e-2)" "unprognostic (5.72e-2)" "unprognostic (4.12e-3)" "unprognostic (3.68e-2)" "unprognostic (3.26e-2)" "unprognostic (3.27e-2)" 4.6 5.2 2.4 2.2 3.1 5.5 4.8 3.7 3.2 4.6 2.5 3.1 2.9 5.2 4.9 3.5 3.7 3.4 5.4 2.2 2.4 3.6 4.2 2.8 2.9 1.9 2.5 5.6 3.9 4.7 2.2 3.9 2.1 4.3 4.7 6.8 2.9 4.2 4.8 6.1 2.6 4.1 2.3 2.1 2.3 36.0 2.3 3.4 7.6 4.6 3.3 3.7 3.1 3.6 5.2 1.5 8.8 6.1 11.7 11.6 2.0 5.9 4.8 2.6 3.9 2.8 4.8 2.0 2.4 2.6 7.9 3.3 10.2 8.3 4.0 3.2 6.0 6.2 8.0 2.1 6.7 4.9 6.3 2.3 2.0 3.0 6.3 6.2 8.9 7.4 3.4 6.5 11.1 1.4 2.7 1.9 4.0 2.3 5.3 4.4 4.0 0.8 5.7 6.2 6.2 3.7 3.4 4.8 4.4 1.5 3.6 3.0 8.8 6.0 5.9 7.9 6.0 1.7 1.3 2.1 5.5 8.2 13.5 0.1 0.9 0.1 1.2 1.1 1.9 2.4 1.8 0.9 0.9 1.3 2.5 1.4 0.2 3.7 0.9 1.8 1.4 1.0 2.4 3.1 3.7 3.2 2.2 2.4 1.9 2.5 2.1 2.3 2.3 3.6 14.4 22.4 9.6 46.0 8.0 17.0 16.7 14.9 23.9 19.7 13.7 15.9 6.7 12.8 12.8 9.2 6.2 13.0 10.8 4.9 9.8 8.5 189.7 8.5 13.8 12.1 5.4 9.9 48.1 8.6 6.7 12.2 8.6 9.5 8.2 15.1 5.0 8.0 8.5 25.2 55.0 9.8 18.3 10.9 8.6 301.2 18.0 12.5 21.4 37.5 6.0 21.8 3.1 68.3 67.9 7.4 5.1 16.1 13.9 12.4 6.8 6.9 10.4 25.2 19.7 15.7 13.3 65.4 14.5 17.6 18.3 6.2 11.3 17.2 9.7 10.6 STAP2 "BKS, STAP-2" ENSG00000178078 "Signal transducing adaptor family member 2" Q9UGK3 19 4324043-4342786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 91.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 294.5;Paneth cells: 343.4;Proximal enterocytes: 415.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 7.9" "Group enriched" "Detected in many" 6 "dendritic cells: 2.2;NK-cells: 7.9;T-cells: 2.5" "Cell line enhanced" "Detected in many" "A-431: 87.3;HaCaT: 70.3;MCF7: 104.3;RT4: 138.1" "Region enriched" "Detected in many" 13 "cerebellum: 20.5" "Low region specificity" "Detected in some" "HPA002375, HPA027761" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA002375: AB_1078285, HPA027761: AB_1845364" "unprognostic (1.42e-1)" "prognostic favorable (2.76e-4)" "unprognostic (3.52e-1)" "prognostic favorable (3.03e-5)" "unprognostic (4.35e-2)" "unprognostic (9.35e-3)" "unprognostic (4.52e-1)" "unprognostic (7.81e-2)" "unprognostic (3.43e-1)" "unprognostic (2.00e-2)" "unprognostic (1.93e-2)" "unprognostic (9.05e-2)" "unprognostic (1.43e-3)" "unprognostic (1.38e-2)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "prognostic favorable (4.13e-4)" 5.6 18.1 2.6 7.5 2.7 0.4 16.6 3.6 4.2 18.1 3.5 72.8 77.5 5.7 10.6 91.0 15.1 7.1 4.9 2.7 2.4 28.5 55.3 8.2 3.2 2.4 2.2 11.5 30.6 21.3 4.4 3.4 2.7 37.9 59.7 0.5 45.4 9.8 1.2 73.9 72.0 4.0 2.0 1.5 24.2 2.0 2.5 7.9 15.3 0.7 13.0 16.5 41.0 2.6 87.3 0.4 6.2 5.8 0.4 4.7 35.7 1.6 8.8 2.8 2.2 52.0 34.8 0.1 13.3 2.8 17.9 70.3 1.1 50.3 1.6 14.9 0.7 0.3 0.4 35.1 10.9 0.1 0.7 3.5 41.7 4.8 12.2 7.0 8.9 2.1 3.4 18.6 1.3 104.3 1.3 0.7 4.8 55.3 20.4 3.6 0.8 2.2 29.4 138.1 2.1 3.5 0.1 25.9 14.6 2.2 60.7 0.3 12.5 0.2 1.2 0.7 1.8 0.1 1.4 1.3 0.3 0.4 5.7 0.4 0.1 0.0 0.6 0.0 2.3 0.6 0.8 0.1 0.7 0.1 2.3 1.4 0.1 7.9 0.0 2.2 2.5 0.8 2.6 2.7 3.6 4.2 2.7 2.4 2.4 2.2 2.7 2.0 2.5 2.6 6.7 9.6 14.4 0.3 2.4 40.5 59.8 171.4 42.7 0.6 33.8 30.1 6.9 38.6 87.2 29.5 0.0 16.9 2.3 294.5 25.4 137.5 1.2 9.0 3.6 10.1 85.8 4.4 1.5 101.0 3.0 4.5 55.5 13.4 8.9 5.2 7.5 29.6 1.8 0.0 1.2 147.5 91.6 4.1 9.4 0.9 4.7 1.8 19.6 0.0 12.5 1.0 1.0 0.5 1.8 139.4 343.4 1.9 1.4 92.6 415.7 125.0 44.9 0.8 0.0 1.7 7.9 0.6 2.6 86.0 61.8 12.4 3.3 5.7 173.2 117.0 STARD13 "ARHGAP37, DLC2, GT650, LINC00464" ENSG00000133121 "StAR related lipid transfer domain containing 13" Q9Y3M8 13 33103137-33350630 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Astrocytes: 212.5;Excitatory neurons: 120.7;Inhibitory neurons: 135.6;Microglial cells: 167.7;Oligodendrocyte precursor cells: 212.6;Oligodendrocytes: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 50.2;TIME: 36.0;WM-115: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039535, HPA058867" Supported NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039535: AB_10965929, HPA058867: AB_2683839" "unprognostic (7.42e-2)" "unprognostic (6.71e-2)" "unprognostic (1.99e-1)" "unprognostic (4.99e-2)" "unprognostic (1.17e-2)" "unprognostic (1.47e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" "unprognostic (1.48e-1)" "unprognostic (7.13e-3)" "unprognostic (3.42e-2)" "unprognostic (4.66e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (5.29e-2)" 16.0 10.9 10.0 5.6 13.2 0.3 11.1 8.7 10.9 16.6 13.4 28.0 4.8 14.8 5.3 7.2 10.4 10.8 12.5 12.6 8.1 8.4 6.1 12.5 2.5 11.1 11.9 7.2 10.8 16.9 4.3 24.6 9.6 9.0 6.8 1.8 6.4 8.1 5.4 5.3 7.0 15.7 8.4 7.4 11.2 2.8 11.7 1.4 20.4 6.3 1.4 14.0 9.6 13.6 11.4 1.6 3.4 2.4 6.8 16.0 0.6 21.2 26.2 17.4 10.8 0.9 4.0 0.1 2.8 10.2 10.7 10.4 1.5 7.5 22.0 10.0 3.6 5.2 3.9 5.2 5.7 0.0 4.6 13.3 4.3 19.7 24.0 9.7 17.1 0.1 0.0 1.7 50.2 3.3 0.0 0.0 2.2 1.2 5.7 0.2 16.6 0.1 10.6 3.2 0.1 5.5 3.2 8.0 2.6 3.0 18.5 4.7 36.0 8.7 9.3 22.0 11.0 2.9 0.0 0.1 7.0 0.1 40.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 10.0 13.2 8.7 10.9 12.6 8.1 11.1 11.9 9.6 8.4 11.7 13.6 30.5 28.9 15.1 212.5 0.1 2.4 2.8 1.1 4.0 5.3 8.6 5.1 19.8 7.2 2.0 9.2 0.0 9.4 4.2 11.8 0.0 7.7 1.2 5.5 26.6 18.4 6.7 0.0 120.7 2.2 3.7 18.8 10.7 6.4 5.1 6.2 17.9 10.7 16.7 5.0 135.6 4.4 0.0 8.8 6.8 1.4 7.2 10.8 14.2 167.7 0.8 1.1 0.0 212.6 470.9 5.5 4.3 7.5 4.7 4.4 3.4 2.1 6.3 0.4 13.1 15.6 33.1 0.1 0.3 1.0 2.3 7.5 0.6 31.1 5.4 1.5 STARD3NL "MENTHO, MGC3251" ENSG00000010270 "STARD3 N-terminal like" O95772 7 38178245-38230670 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019204 Enhanced Supported Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA019204: AB_2197800" "unprognostic (1.55e-3)" "unprognostic (2.80e-3)" "unprognostic (2.22e-1)" "unprognostic (2.58e-1)" "unprognostic (4.37e-2)" "prognostic unfavorable (2.20e-4)" "prognostic unfavorable (1.44e-5)" "unprognostic (9.64e-2)" "unprognostic (1.89e-1)" "unprognostic (5.37e-2)" "prognostic favorable (8.48e-4)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.41e-2)" "unprognostic (8.09e-3)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" 26.8 21.8 35.5 23.1 37.6 37.8 22.0 39.6 41.7 31.4 29.8 21.5 18.5 32.6 27.1 12.3 27.5 22.0 27.1 35.7 44.1 34.0 17.4 32.8 21.3 42.0 46.8 24.2 16.4 17.9 25.5 49.4 48.4 40.6 23.5 26.3 14.9 21.6 17.3 6.6 20.3 33.1 40.5 27.1 17.6 32.7 41.8 22.3 32.7 17.5 15.3 29.4 14.8 42.9 40.9 42.7 92.6 60.4 62.8 62.2 32.4 65.2 67.2 63.2 82.4 34.3 63.0 31.9 64.0 59.9 192.0 42.9 51.4 49.5 95.2 29.0 45.1 64.8 22.1 47.4 55.3 71.5 72.7 58.8 24.0 67.0 53.0 72.0 116.7 86.1 75.0 53.7 98.4 25.1 40.9 115.2 65.5 33.7 33.9 49.6 85.9 14.9 89.0 37.5 36.9 86.7 22.4 58.8 64.1 127.0 40.9 93.8 80.0 43.0 61.0 67.8 93.5 57.4 62.2 12.1 87.0 125.6 142.4 33.5 46.8 56.2 52.2 43.3 23.9 30.8 21.6 39.3 42.3 28.4 18.1 35.6 53.1 71.8 47.0 30.3 24.8 47.1 35.5 37.6 39.6 41.7 35.7 44.1 42.0 46.8 48.4 40.5 41.8 42.9 45.8 19.2 47.3 15.0 33.2 20.8 57.3 43.4 20.5 8.7 26.8 15.0 18.2 14.3 25.9 31.3 12.5 48.3 67.2 15.5 31.3 31.4 125.3 37.0 42.5 45.5 21.5 28.2 21.9 34.3 91.2 34.2 19.9 33.1 23.5 36.0 51.0 12.4 65.8 5.0 24.5 20.9 32.6 63.2 77.9 115.2 18.3 56.8 26.6 17.8 24.2 34.6 114.4 27.6 26.0 34.0 21.6 25.9 34.3 55.2 19.4 50.1 22.8 13.0 13.1 23.4 38.4 48.8 37.3 12.2 16.2 42.3 47.5 24.5 19.5 46.4 STARD4 ENSG00000164211 "StAR related lipid transfer domain containing 4" Q96DR4 5 111496033-111512590 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046177, HPA048081" Approved Approved "Plasma membrane" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "HPA046177: AB_2679570, HPA048081: AB_2680253" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (1.01e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (4.80e-5)" "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (4.26e-1)" "unprognostic (6.27e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (2.00e-1)" "unprognostic (3.82e-3)" "unprognostic (4.01e-3)" "prognostic unfavorable (2.84e-4)" 6.2 15.8 8.3 15.9 15.8 19.4 3.9 25.2 12.6 10.2 11.5 14.7 40.8 7.7 16.2 8.5 5.0 9.7 15.0 9.5 10.6 8.5 34.1 20.9 12.6 16.0 16.7 6.5 6.1 14.4 8.2 27.3 13.8 20.7 16.9 12.0 6.6 9.9 1.5 2.5 35.7 6.9 10.1 12.1 17.9 6.8 14.8 7.2 9.0 1.7 10.1 7.7 9.2 11.3 20.6 10.0 48.2 29.4 42.4 84.0 16.3 21.0 46.6 29.8 89.1 37.7 59.9 24.5 8.4 13.4 89.0 9.1 24.8 71.8 28.8 23.7 10.4 19.1 33.3 22.8 46.4 9.5 11.7 44.6 48.3 64.1 47.6 35.6 56.6 23.5 10.7 46.5 20.8 3.9 23.7 17.3 16.6 0.6 5.5 5.4 53.3 22.5 44.6 6.7 27.2 105.6 0.0 12.3 19.0 32.1 16.0 30.4 84.4 25.6 22.9 17.2 8.9 15.9 15.8 21.6 24.3 34.8 13.2 7.1 1.4 0.9 2.5 2.1 1.3 1.7 1.2 1.9 1.8 1.7 1.2 1.9 0.0 2.1 1.5 1.3 0.8 1.4 8.3 15.8 25.2 12.6 9.5 10.6 16.0 16.7 13.8 10.1 14.8 11.3 8.2 25.6 34.8 16.0 13.1 1.0 1.4 35.0 1.2 10.8 1.6 0.4 17.8 8.6 18.1 9.2 8.4 15.6 24.8 37.3 1.9 7.8 9.4 6.7 3.5 20.2 21.4 3.6 38.8 9.2 6.0 6.0 15.8 11.5 32.3 6.5 5.0 39.9 20.3 6.7 20.8 32.5 22.4 19.6 26.7 8.3 7.2 27.8 3.6 20.6 5.7 7.1 9.2 20.1 23.6 10.0 30.0 7.9 17.6 3.3 30.1 5.7 9.5 7.6 19.7 2.4 15.2 8.7 9.4 6.8 2.6 14.1 14.5 38.2 23.0 5.2 STC2 STC-2 ENSG00000113739 "Stanniocalcin 2" O76061 5 173314723-173328447 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 143.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 278.3;Breast myoepithelial cells: 119.6;Extravillous trophoblasts: 59.5" "Cancer enriched" "Detected in all" 6 "breast cancer: 91.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 1019.9;T-47d: 940.0;U-138 MG: 382.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA045372 Approved Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA 19000000 "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "Endoplasmic reticulum" "HPA045372: AB_10961040" "prognostic favorable (7.40e-5)" "unprognostic (2.40e-2)" "unprognostic (9.03e-3)" "unprognostic (1.21e-1)" "unprognostic (1.89e-3)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (3.07e-5)" "unprognostic (5.28e-3)" "unprognostic (6.12e-3)" "unprognostic (1.53e-1)" "unprognostic (2.13e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.17e-8)" "prognostic unfavorable (7.57e-4)" "unprognostic (8.56e-2)" "unprognostic (5.06e-2)" "unprognostic (7.93e-3)" 7.4 1.7 0.7 2.4 0.9 0.0 143.6 2.2 3.1 13.2 1.9 4.8 0.6 3.0 0.3 2.0 2.0 6.4 9.9 3.0 1.8 3.6 0.8 11.3 1.1 5.0 6.4 0.7 32.6 3.3 1.7 28.0 3.7 4.8 0.6 7.7 1.0 6.7 4.4 12.8 2.7 21.2 1.3 11.5 3.4 0.7 2.9 0.2 9.1 4.9 0.3 4.7 3.0 3.0 52.5 15.3 2.7 13.0 47.9 20.5 133.8 234.5 239.4 59.1 115.0 74.4 36.7 0.0 33.4 139.8 298.2 21.5 33.8 72.0 102.5 0.1 18.9 0.0 26.7 50.2 311.3 15.8 4.3 43.6 117.9 133.3 7.9 274.4 16.7 42.4 2.4 0.1 1019.9 41.6 0.7 0.7 7.9 23.4 73.2 0.3 36.5 27.4 0.0 3.9 35.6 9.6 10.3 1.1 42.5 10.4 940.0 15.9 151.5 382.8 1.3 229.1 49.2 42.0 24.3 10.5 74.6 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 2.2 3.1 3.0 1.8 5.0 6.4 3.7 1.3 2.9 3.0 6.9 0.0 0.0 0.0 0.4 5.0 0.2 4.9 0.6 11.1 278.3 119.6 27.1 0.0 0.6 0.0 0.0 37.0 2.4 0.4 0.0 31.6 0.6 9.5 1.0 25.3 7.2 0.0 0.2 13.1 59.5 16.7 0.0 16.1 0.0 0.0 3.6 0.0 5.2 0.0 0.2 0.2 0.0 0.0 4.8 1.0 23.0 0.5 10.6 1.0 0.0 0.9 0.0 0.0 0.1 7.8 0.0 0.4 0.0 0.8 0.0 4.5 0.2 2.4 0.0 2.3 24.6 0.7 0.8 0.5 6.3 21.9 1.0 0.9 0.4 0.5 STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 402.5;Club cells: 152.8;Sertoli cells: 460.2;Smooth muscle cells: 255.3" "Cancer enhanced" "Detected in many" "prostate cancer: 45.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 12 "neutrophil: 163.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 163.6" "Group enriched" "Detected in some" 6 "HSkMC: 122.1;SiHa: 119.7;U-2197: 166.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "prognostic favorable (2.97e-4)" "unprognostic (7.40e-2)" "unprognostic (3.12e-1)" "unprognostic (4.66e-2)" "unprognostic (4.21e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (4.53e-2)" 113.7 46.3 1.0 31.7 0.9 7.1 68.6 2.8 1.5 21.3 17.0 13.3 3.8 17.9 7.8 15.4 36.1 22.7 24.1 1.4 1.0 11.8 24.3 67.5 7.2 1.2 0.9 4.4 10.6 16.0 13.0 15.3 0.8 60.0 9.2 1.9 26.8 10.6 13.4 19.3 10.6 29.3 0.4 5.4 10.6 13.4 1.1 7.8 53.1 16.6 5.1 34.3 22.7 1.1 4.9 0.0 0.1 0.1 0.1 1.9 0.3 0.0 0.3 0.0 0.1 0.1 23.6 0.1 0.1 0.0 0.4 18.7 0.1 0.0 0.1 0.0 0.1 0.1 7.9 0.1 0.1 0.1 0.2 122.1 0.1 0.4 0.9 0.0 0.0 0.1 0.3 0.4 0.0 3.0 0.1 0.5 0.1 1.0 0.0 0.2 0.1 0.3 0.0 0.3 0.2 0.2 119.7 9.9 0.0 0.1 0.8 0.0 0.1 0.4 0.3 166.4 0.1 0.1 0.1 0.1 0.2 0.9 0.2 0.4 13.5 1.4 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 163.6 0.2 0.1 0.3 0.0 3.2 1.0 0.9 2.8 1.5 1.4 1.0 1.2 0.9 0.8 0.4 1.1 1.1 77.2 54.5 402.5 0.0 0.8 9.4 5.8 8.6 1.8 1.8 21.6 8.3 9.1 0.0 152.8 0.0 2.1 0.4 1.1 0.4 0.0 14.6 23.8 14.6 20.5 14.7 0.0 0.0 0.5 9.6 10.6 39.8 1.1 51.2 16.4 0.0 15.4 0.7 2.8 0.0 0.8 0.2 16.2 7.2 7.4 10.9 114.9 12.2 5.4 6.5 19.0 2.7 0.0 1.0 0.1 18.6 0.0 9.1 0.2 49.3 0.1 0.1 72.8 0.3 460.2 9.6 255.3 0.9 0.3 1.5 18.8 10.9 3.1 57.7 0.2 16.6 STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Glandular and luminal cells: 12.4;Spermatocytes: 17.8;Spermatogonia: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046543 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA046543: AB_2679692" "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" 1.0 0.5 0.8 3.0 0.8 10.8 2.9 0.7 1.2 1.1 0.2 4.1 2.9 1.4 1.4 2.5 0.9 1.4 0.6 0.8 0.6 0.7 1.0 0.9 4.9 0.7 0.6 0.8 0.7 0.9 0.4 1.9 0.8 1.3 5.6 1.2 1.7 0.5 0.6 3.1 2.7 1.4 0.4 1.4 1.8 6.6 0.8 9.9 0.9 0.7 5.7 1.1 1.0 1.0 33.7 17.4 24.7 22.1 1.8 3.8 15.7 29.3 14.0 32.0 33.2 18.5 16.1 39.4 13.3 14.4 32.7 21.4 29.4 15.3 33.7 29.6 12.9 44.5 20.9 16.6 0.8 35.7 21.5 1.6 2.1 27.2 17.5 3.8 21.5 29.5 31.7 35.9 24.1 14.3 35.6 10.9 30.0 18.6 14.2 23.0 40.3 19.0 9.0 20.0 22.0 13.2 31.4 22.2 14.6 29.6 14.5 20.6 12.2 29.6 29.9 21.2 40.0 11.9 26.4 38.1 13.8 27.0 28.0 0.3 0.1 0.2 0.2 0.0 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.7 0.0 0.3 0.3 0.1 0.8 0.8 0.7 1.2 0.8 0.6 0.7 0.6 0.8 0.4 0.8 1.0 1.6 3.2 0.5 2.0 2.4 0.9 0.6 2.0 1.2 1.1 2.8 3.0 0.5 0.0 2.3 0.0 4.2 2.5 1.6 5.4 0.0 1.6 1.6 7.8 3.2 2.2 1.8 12.8 5.1 0.4 4.4 1.6 3.1 12.4 2.5 8.2 1.4 0.5 2.9 0.0 3.9 6.1 0.0 2.4 1.2 1.1 0.3 2.7 0.0 0.0 3.0 0.8 1.0 2.0 4.8 1.9 1.8 0.7 10.2 1.1 1.4 0.4 7.6 0.6 0.0 1.7 2.0 17.8 14.4 5.3 2.4 0.8 3.3 2.6 5.5 1.4 STMN3 SCLIP ENSG00000197457 "Stathmin 3" Q9NZ72 20 63639705-63657682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 291.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.5;Granulosa cells: 254.2;Horizontal cells: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in many" 5 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "AN3-CA: 125.1;MOLT-4: 142.0;REH: 143.8;SCLC-21H: 192.5;SH-SY5Y: 146.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012947 Enhanced Supported "Golgi apparatus,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 14: REH - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" Cytosol "HPA012947: AB_1857606" "unprognostic (7.59e-2)" "unprognostic (4.36e-1)" "unprognostic (5.28e-2)" "unprognostic (2.33e-1)" "unprognostic (3.60e-2)" "unprognostic (6.30e-2)" "unprognostic (2.75e-1)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "unprognostic (4.35e-2)" "unprognostic (1.65e-3)" "unprognostic (7.52e-2)" "unprognostic (2.52e-3)" "unprognostic (2.73e-2)" "unprognostic (9.87e-2)" "unprognostic (4.08e-2)" "unprognostic (9.08e-3)" 23.4 49.7 188.4 21.3 197.6 11.4 20.0 112.5 291.7 29.2 16.6 26.5 5.5 30.0 5.0 11.6 27.9 10.9 17.1 215.0 162.0 24.8 3.7 23.6 25.8 259.6 158.1 50.5 16.4 17.5 102.2 10.0 266.1 24.3 5.2 38.8 11.7 12.7 4.3 20.2 24.8 14.7 100.8 48.2 15.1 9.0 159.3 43.5 63.9 3.7 12.4 21.9 19.0 179.9 10.4 11.6 74.4 125.1 1.9 7.3 5.1 12.0 0.4 35.8 16.8 73.6 13.7 0.5 36.3 4.6 2.0 68.6 52.2 1.3 11.1 5.2 14.0 5.1 17.0 27.6 9.9 3.9 42.0 15.3 0.3 11.5 2.9 1.5 1.3 34.4 98.8 2.2 9.6 11.7 142.0 17.7 76.5 2.4 81.7 143.8 12.1 58.0 60.9 2.0 192.5 146.6 5.7 3.4 14.9 5.9 2.1 25.9 1.9 0.8 20.4 0.8 2.6 4.9 10.4 3.6 2.1 14.3 48.8 1.1 0.0 1.1 2.5 0.1 2.7 0.2 5.2 4.5 0.1 0.6 6.2 5.3 0.1 0.0 0.1 1.1 0.9 2.0 188.4 197.6 112.5 291.7 215.0 162.0 259.6 158.1 266.1 100.8 159.3 179.9 5.8 6.4 2.5 16.3 17.1 8.2 6.9 11.9 8.6 108.5 4.7 14.7 2.3 4.3 3.2 3.7 52.1 11.7 13.4 1.1 13.7 4.0 10.0 1.6 17.9 7.8 37.2 4.6 56.9 2.5 4.0 25.4 2.0 2.7 4.5 254.2 6.8 0.0 2.3 109.4 67.1 0.6 4.1 2.2 7.6 18.8 30.1 3.5 7.2 7.5 4.6 37.2 16.5 21.1 11.3 2.2 0.1 35.7 5.3 4.5 0.1 5.0 0.8 44.5 13.1 3.0 20.9 3.3 6.7 1.6 4.3 8.8 28.6 51.0 0.6 2.7 STRA6 FLJ12541 ENSG00000137868 "Signaling receptor and transporter of retinol STRA6" Q9BX79 15 74179466-74212267 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Receptor "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.5" "Cell type enhanced" "Detected in many" "Club cells: 17.6;Endometrial stromal cells: 43.1;Extravillous trophoblasts: 12.1;Fibroblasts: 16.1;Proximal tubular cells: 10.3;Syncytiotrophoblasts: 26.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 33.7;CAPAN-2: 94.5;SH-SY5Y: 59.2;WM-115: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040839 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA040839: AB_10794881" "unprognostic (1.20e-2)" "unprognostic (4.99e-2)" "unprognostic (3.71e-2)" "unprognostic (3.55e-3)" "unprognostic (1.37e-1)" "unprognostic (2.09e-2)" "unprognostic (4.38e-3)" "unprognostic (1.67e-2)" "unprognostic (9.16e-2)" "unprognostic (1.21e-1)" "unprognostic (5.35e-2)" "unprognostic (3.89e-1)" "unprognostic (7.91e-13)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-2)" "unprognostic (1.91e-1)" 0.1 1.0 0.1 0.3 0.0 0.0 0.9 0.0 0.4 24.5 0.4 0.1 0.0 4.3 0.5 1.1 3.6 0.3 0.1 0.1 0.1 4.3 0.0 0.2 0.8 0.1 0.0 0.6 0.1 0.0 5.5 7.6 0.0 5.2 0.0 0.0 0.7 1.4 0.0 0.3 0.2 0.2 0.1 0.1 0.0 3.1 0.3 0.2 0.1 0.1 0.5 1.3 2.4 0.0 0.5 33.7 1.9 0.1 0.0 0.0 6.0 1.0 0.2 0.0 0.0 11.7 94.5 0.0 22.1 0.1 0.7 3.4 1.8 0.0 0.0 0.0 0.2 3.0 1.3 2.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.4 6.1 0.6 2.9 0.1 0.0 0.4 0.0 0.0 0.0 2.9 17.4 59.2 0.0 3.6 0.0 3.6 0.2 0.1 0.0 0.2 7.3 0.6 1.6 0.1 0.2 0.0 0.6 0.0 142.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.4 1.0 9.7 0.0 0.0 0.2 0.3 1.0 0.0 17.6 0.0 0.0 4.2 0.0 0.0 1.9 0.3 1.7 2.1 43.1 1.3 0.0 0.0 0.1 0.0 12.1 16.1 0.0 1.8 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 2.0 0.0 0.8 0.8 6.8 0.4 1.8 1.9 0.1 0.0 0.0 0.0 0.0 4.7 0.0 4.1 0.0 0.4 0.0 10.3 6.6 0.0 0.0 1.3 4.7 0.5 0.5 0.0 0.0 26.4 0.3 0.1 0.0 1.3 STX2 "EPIM, EPM, STX2A, STX2B, STX2C" ENSG00000111450 "Syntaxin 2" P32856 12 130789600-130839266 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 152.2;Endometrial ciliated cells: 86.4;Late spermatids: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079007" Uncertain Supported Approved "Nuclear membrane,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "Nuclear membrane" "CAB079007: , HPA069176: AB_2686098" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (8.29e-2)" "unprognostic (2.22e-1)" "unprognostic (3.38e-2)" "unprognostic (9.85e-2)" "unprognostic (2.11e-2)" "unprognostic (4.16e-2)" "unprognostic (2.83e-1)" "unprognostic (7.62e-2)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.15e-5)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.63e-2)" "unprognostic (3.41e-3)" 17.7 11.0 11.2 9.1 11.7 6.4 12.0 12.3 13.4 15.1 24.7 21.2 4.2 14.3 9.8 6.0 16.3 9.9 17.0 12.2 12.1 14.4 13.3 17.8 8.6 15.5 12.3 15.3 10.9 5.9 14.6 13.2 14.5 8.4 6.8 16.7 5.0 10.6 6.7 5.1 11.4 17.2 13.0 12.4 11.4 17.0 11.8 6.9 12.4 7.9 6.2 14.5 10.7 16.3 9.6 18.3 26.8 22.4 27.8 63.2 2.8 44.2 35.8 50.8 35.7 5.5 6.6 11.7 6.6 50.5 16.4 2.8 24.4 6.6 54.9 18.7 9.2 6.4 15.9 15.7 30.6 9.2 15.5 23.4 8.3 24.9 20.1 48.2 27.6 12.7 25.7 11.2 46.2 5.6 13.3 10.6 17.9 2.9 28.2 13.7 18.9 7.0 28.7 2.1 24.3 25.4 20.4 1.8 18.1 23.4 6.1 6.4 36.5 30.1 20.3 33.1 19.6 8.1 6.7 7.9 35.0 10.8 24.4 1.0 0.4 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.3 0.3 0.6 0.6 0.4 0.2 0.2 0.3 0.4 0.2 11.2 11.7 12.3 13.4 12.2 12.1 15.5 12.3 14.5 13.0 11.8 16.3 35.3 22.4 14.8 20.5 6.2 3.4 1.2 2.1 3.4 5.6 2.1 3.0 17.2 11.5 6.9 29.5 0.0 1.8 12.3 0.4 9.8 19.1 152.2 86.4 40.0 22.4 6.7 32.4 33.6 7.4 7.1 26.5 2.6 7.6 1.3 10.9 17.9 19.0 11.5 0.0 17.6 0.7 2.0 11.5 12.3 114.4 28.0 15.1 14.2 23.4 10.3 12.3 6.2 15.1 24.3 14.5 0.1 24.5 10.2 2.0 0.1 17.6 33.9 31.4 13.1 26.1 29.6 42.0 34.2 1.7 1.4 0.8 14.2 11.7 0.6 0.5 SULT1C4 "SULT1C, SULT1C2" ENSG00000198075 "Sulfotransferase family 1C member 4" O75897 2 108377911-108388989 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 13.3;Cholangiocytes: 37.1;Endothelial cells: 13.2;Granulosa cells: 15.3;Hepatic stellate cells: 17.9;Muller glia cells: 12.3;Oligodendrocyte precursor cells: 17.6" "Group enriched" "Detected in many" 6 "glioma: 7.1;renal cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.5;HUVEC TERT2: 10.7;SH-SY5Y: 42.0;SuSa: 11.6" "Low region specificity" "Detected in many" HPA034530 Approved Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA034530: AB_10670170" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-1)" "unprognostic (2.89e-1)" "unprognostic (5.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-2)" "unprognostic (5.77e-2)" "unprognostic (1.56e-3)" "unprognostic (1.68e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-3)" "prognostic favorable (9.99e-7)" "unprognostic (1.79e-2)" "unprognostic (2.96e-2)" "unprognostic (1.85e-2)" "unprognostic (1.38e-1)" 6.2 2.0 15.5 1.1 16.1 0.5 5.2 16.9 17.2 21.9 12.9 3.4 1.5 11.1 8.0 2.3 9.3 27.1 10.9 13.6 18.9 18.2 3.7 10.3 1.8 18.8 27.3 27.9 2.9 1.0 5.2 13.0 20.4 6.6 2.2 8.6 1.6 8.9 3.1 0.7 3.2 5.5 18.1 1.4 2.0 1.4 19.0 5.0 4.5 6.2 1.3 3.8 5.3 15.8 0.0 0.1 9.5 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 4.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.0 1.2 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 42.0 0.0 0.0 0.0 11.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 15.5 16.1 16.9 17.2 13.6 18.9 18.8 27.3 20.4 18.1 19.0 15.8 13.3 0.0 0.5 10.4 0.0 0.3 0.7 0.0 0.0 2.0 0.4 0.3 0.7 37.1 0.0 9.2 0.0 0.3 0.0 0.0 0.0 0.3 5.9 10.9 3.1 13.2 0.0 2.7 0.6 0.2 0.1 4.9 0.0 3.8 0.0 15.3 17.9 0.0 0.9 1.7 0.5 0.0 0.0 1.3 1.0 1.1 1.5 0.4 0.0 7.5 0.1 12.3 0.0 17.6 0.4 0.1 0.0 4.5 1.4 0.7 0.0 7.7 0.0 1.0 0.0 1.4 1.8 0.6 0.7 0.0 0.4 0.3 0.2 7.2 0.0 0.2 SUSD5 KIAA0527 ENSG00000173705 "Sushi domain containing 5" O60279 3 33150043-33218810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Excitatory neurons: 15.4;Inhibitory neurons: 10.5;Oligodendrocyte precursor cells: 61.3;Sertoli cells: 32.9;Smooth muscle cells: 29.0" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.1;HUVEC TERT2: 78.5;LHCN-M2: 30.4;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052788 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA 17000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "HPA052788: AB_2681948" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-3)" "unprognostic (1.39e-3)" "unprognostic (4.05e-2)" "unprognostic (3.72e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-3)" "unprognostic (6.45e-2)" "unprognostic (8.46e-2)" "unprognostic (1.89e-2)" 4.6 1.4 2.9 0.9 3.0 0.1 1.9 2.2 4.6 6.3 4.4 1.7 0.8 4.6 2.2 1.3 5.2 5.5 1.5 3.1 4.4 1.5 0.5 1.7 2.3 3.4 3.4 3.8 0.6 1.0 0.8 0.2 3.4 1.3 1.2 0.6 0.7 6.3 1.6 1.9 1.9 4.8 3.8 2.5 1.8 2.1 4.7 0.1 3.2 3.3 5.3 1.5 2.4 3.5 0.0 1.1 1.2 0.7 1.7 0.2 0.1 9.6 3.4 31.1 10.5 0.1 0.0 0.0 8.8 2.5 9.5 0.1 13.7 4.5 12.9 0.3 15.3 0.0 2.0 0.0 0.2 0.1 0.1 1.3 2.4 19.9 3.9 15.2 78.5 0.0 0.0 0.1 30.4 0.0 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.0 1.0 0.1 0.1 2.5 0.7 1.8 1.9 31.3 0.0 14.4 1.2 4.7 0.0 0.7 0.0 0.3 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.9 3.0 2.2 4.6 3.1 4.4 3.4 3.4 3.4 3.8 4.7 3.5 0.1 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 2.2 0.5 0.0 0.0 15.4 0.0 0.1 1.4 0.0 0.9 0.0 0.2 0.4 0.0 0.0 3.3 10.5 0.0 0.0 2.1 2.0 0.3 0.0 0.1 1.8 0.0 0.0 0.5 0.0 61.3 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 32.9 3.6 29.0 0.1 2.6 0.1 1.0 0.0 0.2 0.1 0.0 0.1 SYCP2 SCP2 ENSG00000196074 "Synaptonemal complex protein 2" Q9BX26 20 59863564-59933655 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 43.2" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 468.5" "Group enriched" "Detected in many" 6 "breast cancer: 6.7;cervical cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 25.9;JURKAT: 47.2;MOLT-4: 54.4;SiHa: 92.2;T-47d: 82.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA062401, HPA065613" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA062401: AB_2684752, HPA065613: AB_2685519" "unprognostic (8.10e-3)" "unprognostic (8.28e-3)" "unprognostic (1.62e-1)" "unprognostic (2.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.19e-3)" "unprognostic (2.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.11e-2)" "unprognostic (1.44e-1)" "unprognostic (3.74e-1)" "unprognostic (7.02e-3)" "unprognostic (4.84e-3)" "unprognostic (8.48e-2)" "unprognostic (2.46e-1)" "unprognostic (7.87e-3)" "unprognostic (1.21e-1)" 3.2 0.8 2.2 1.4 2.8 2.4 13.9 9.7 4.9 2.4 0.0 1.3 1.6 1.6 1.2 0.9 1.3 2.4 2.5 2.2 1.1 4.3 1.1 2.2 2.6 1.8 1.8 0.7 6.6 0.7 1.9 3.9 2.2 3.8 1.1 1.5 4.4 1.0 1.3 2.7 2.4 0.7 1.4 3.1 6.1 43.2 2.5 1.3 2.4 1.0 1.7 1.8 1.5 4.1 0.3 1.3 0.2 1.4 0.6 0.8 1.4 4.1 1.1 1.8 0.2 25.9 2.6 0.1 4.0 1.8 0.8 0.6 0.5 0.1 1.0 8.5 0.6 0.2 6.1 0.4 0.2 0.4 19.0 0.4 0.4 0.4 0.0 0.9 0.0 47.2 0.2 0.0 0.9 12.5 54.4 2.9 0.4 1.5 0.3 0.0 0.1 0.2 2.1 6.1 0.2 4.5 92.2 13.3 3.3 1.6 82.6 4.7 0.5 0.1 2.8 11.2 0.0 0.0 0.0 0.0 0.0 1.7 5.2 0.7 0.1 0.7 0.8 0.0 0.8 0.2 0.4 0.5 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.0 0.3 0.2 2.2 2.8 9.7 4.9 2.2 1.1 1.8 1.8 2.2 1.4 2.5 4.1 11.5 0.0 1.1 24.5 1.4 1.0 1.1 1.0 0.0 1.9 12.7 9.4 3.6 2.8 6.3 1.8 2.1 0.8 3.0 0.1 1.9 0.9 82.3 0.4 5.0 6.5 0.0 0.0 27.5 3.6 0.4 2.1 2.6 0.5 2.5 1.2 2.9 0.0 0.5 0.0 14.6 0.1 0.0 1.2 0.8 21.8 4.7 1.6 5.4 13.1 1.4 2.3 5.2 28.6 11.1 1.2 1.2 1.9 0.4 1.8 0.3 5.4 8.6 1.1 52.6 1.7 3.8 468.5 92.4 0.6 0.0 0.4 4.1 0.2 0.3 1.2 SYNM "DMN, KIAA0353, SYN" ENSG00000182253 Synemin O15061 15 99098217-99135593 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 594.1;skeletal muscle: 624.7;urinary bladder: 406.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 103.5;Cardiomyocytes: 502.5;Muller glia cells: 127.8;Smooth muscle cells: 98.5" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.8;HeLa: 58.0;WM-115: 124.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017192, HPA040066, HPA044200, HPA077856" Enhanced Supported "Intermediate filaments" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB017192: , HPA040066: AB_2676830, HPA044200: AB_2678854, HPA077856: AB_2686861" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-2)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (1.00e-1)" "unprognostic (1.34e-2)" "unprognostic (6.75e-2)" "unprognostic (3.54e-3)" "unprognostic (2.80e-2)" "unprognostic (7.27e-2)" "unprognostic (5.92e-3)" "unprognostic (3.26e-3)" 37.2 20.3 51.4 26.5 66.0 0.4 56.7 70.1 58.2 11.8 52.5 594.1 27.1 50.8 12.7 169.6 36.5 19.2 144.2 44.4 75.4 6.9 4.8 23.1 4.2 81.7 66.6 14.1 6.3 8.2 23.2 14.0 81.6 150.6 52.0 40.3 25.6 291.3 624.7 17.0 105.7 160.9 71.6 2.9 158.4 5.2 69.3 3.7 11.2 277.1 4.0 406.3 41.0 79.8 6.6 36.8 8.1 21.9 15.9 0.9 0.5 3.7 5.3 2.1 1.3 5.4 4.9 0.0 5.3 5.3 17.7 4.2 5.5 0.1 1.6 0.5 9.0 0.1 58.0 5.4 9.0 0.0 1.0 0.9 0.3 3.7 0.8 6.0 4.3 0.0 0.2 7.4 5.5 3.7 0.7 0.8 7.2 0.7 11.4 0.0 7.5 5.5 2.1 3.6 3.6 4.2 21.9 3.4 13.5 12.7 0.2 3.6 4.8 4.1 0.4 2.9 8.9 0.1 1.0 0.0 0.4 0.0 124.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 51.4 66.0 70.1 58.2 44.4 75.4 81.7 66.6 81.6 71.6 69.3 79.8 14.8 0.0 1.7 15.3 0.9 2.3 0.7 0.9 2.8 12.6 32.7 103.5 502.5 0.0 1.2 0.0 16.7 1.5 6.6 2.1 0.0 0.5 9.5 1.3 1.0 24.2 3.0 0.0 15.6 1.3 0.7 20.3 5.1 4.2 0.0 1.1 3.6 1.3 0.3 42.1 9.8 0.9 0.0 0.0 5.1 4.5 1.2 2.0 5.4 12.2 0.6 127.8 1.0 2.5 14.0 0.2 2.3 4.1 5.4 2.0 0.6 0.3 3.1 10.2 32.9 19.6 98.5 7.9 11.5 2.1 3.7 0.4 5.9 0.2 0.7 0.9 SYPL2 Mg29 ENSG00000143028 "Synaptophysin like 2" Q5VXT5 1 109466546-109482134 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "skeletal muscle: 363.5;tongue: 175.3" "Cell type enhanced" "Detected in some" "Astrocytes: 5.5;Cardiomyocytes: 10.6;Collecting duct cells: 3.7;Hepatocytes: 4.8;Late spermatids: 11.1;Proximal tubular cells: 5.1;Skeletal myocytes: 4.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.2;BJ: 14.1;BJ hTERT+: 44.1;fHDF/TERT166: 23.1;HAP1: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076657 Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA076657: " "unprognostic (1.82e-2)" "unprognostic (1.81e-1)" "unprognostic (2.90e-4)" "unprognostic (6.63e-2)" "unprognostic (1.35e-1)" "unprognostic (9.36e-3)" "unprognostic (2.84e-2)" "unprognostic (2.57e-1)" "unprognostic (2.35e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "prognostic favorable (3.05e-4)" "unprognostic (2.54e-3)" "unprognostic (3.40e-1)" "unprognostic (9.46e-3)" "unprognostic (6.39e-4)" 2.8 11.7 1.5 0.6 1.5 0.0 1.5 1.3 2.4 4.0 4.0 6.2 0.5 6.6 4.5 4.6 1.4 0.9 19.9 1.6 1.3 9.6 9.5 1.3 0.5 1.4 1.3 3.0 5.1 5.8 1.1 3.2 1.2 3.1 1.0 0.4 4.2 6.0 363.5 0.7 1.6 6.0 1.0 1.1 3.2 9.3 1.6 0.1 8.0 175.3 0.3 4.1 2.4 1.3 0.0 0.1 0.1 1.8 31.6 13.2 0.0 14.1 44.1 4.3 1.6 0.0 0.1 0.0 0.0 23.1 0.5 0.0 11.8 0.0 0.9 0.0 5.1 0.0 0.4 0.2 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.1 0.1 0.0 1.4 3.3 2.3 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.5 1.3 2.4 1.6 1.3 1.4 1.3 1.2 1.0 1.6 1.3 0.2 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 10.6 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.2 2.8 0.0 0.1 0.4 0.0 0.0 0.3 1.3 0.0 1.0 0.0 0.0 0.0 0.9 0.0 4.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.1 0.0 5.1 0.0 0.0 0.0 4.8 2.6 0.4 1.4 0.0 0.0 0.1 0.2 0.4 0.0 0.0 SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 336.8" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.1;NTERA-2: 8.8;RPTEC TERT1: 56.8;SCLC-21H: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" 0.1 4.7 7.0 1.5 12.7 0.0 0.2 1.7 30.1 0.0 0.0 12.2 12.5 0.2 0.0 0.0 0.2 20.8 5.2 18.0 11.5 8.9 0.3 0.5 0.0 5.7 1.2 0.0 7.1 0.4 16.8 0.0 5.4 1.8 12.6 11.3 1.9 0.0 0.1 0.2 12.8 0.8 0.0 0.1 11.0 1.7 9.0 0.3 1.6 0.1 0.0 0.0 0.0 5.2 0.0 19.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 8.8 0.0 0.2 0.0 0.0 0.0 56.8 0.0 15.0 0.7 0.0 0.0 0.1 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 12.7 1.7 30.1 18.0 11.5 5.7 1.2 5.4 0.0 9.0 5.2 0.0 0.0 0.0 4.6 0.1 0.0 0.2 0.0 0.0 3.3 0.1 0.3 15.3 17.2 0.0 3.7 25.0 0.0 0.0 10.2 5.9 1.2 3.1 0.4 0.2 0.1 336.8 0.0 41.6 0.6 0.0 1.7 3.6 2.0 0.0 2.5 0.0 0.0 0.0 1.7 43.8 37.3 4.1 0.0 0.0 9.7 0.3 0.0 0.0 5.6 0.0 0.7 0.0 1.5 3.5 8.2 14.3 0.0 0.0 2.3 13.9 0.5 0.0 2.7 0.0 0.0 0.2 2.0 0.2 0.0 0.0 0.0 0.0 0.0 32.8 0.2 SYT8 DKFZp434K0322 ENSG00000149043 "Synaptotagmin 8" Q8NBV8 11 1828307-1837521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.2;skin 1: 65.5;urinary bladder: 40.5" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 184.7;Basal squamous epithelial cells: 520.2;Breast myoepithelial cells: 192.9;Cholangiocytes: 183.0;Extravillous trophoblasts: 201.8;Respiratory ciliated cells: 163.8;Squamous epithelial cells: 132.5" "Group enriched" "Detected in many" 5 "cervical cancer: 10.5;pancreatic cancer: 21.7;urothelial cancer: 33.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CAPAN-2: 32.2;hTCEpi: 50.2;T-47d: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047239, HPA052700" Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA047239: , HPA052700: AB_2681920" "unprognostic (1.66e-3)" "unprognostic (2.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.14e-1)" "unprognostic (6.31e-2)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (1.36e-2)" "unprognostic (1.02e-1)" "unprognostic (8.25e-2)" "unprognostic (7.09e-2)" "unprognostic (2.48e-1)" "unprognostic (2.33e-6)" "unprognostic (2.87e-2)" "unprognostic (1.75e-1)" "unprognostic (5.52e-2)" "unprognostic (2.77e-2)" 0.1 0.2 0.0 0.0 0.0 0.0 5.1 0.0 0.0 1.3 0.1 0.4 0.5 0.0 0.5 29.2 1.0 8.6 0.0 0.0 0.0 0.3 0.6 4.7 0.0 0.0 0.0 0.0 14.9 0.0 0.2 1.6 0.0 2.5 0.0 0.0 20.9 2.9 0.0 65.5 2.5 0.0 0.0 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.1 40.5 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 32.2 0.0 0.0 0.0 0.6 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 50.2 0.0 5.8 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 5.7 0.0 0.0 0.3 0.0 0.1 1.0 0.0 0.3 0.0 2.7 0.0 0.0 13.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 16.0 3.9 0.0 0.3 184.7 5.6 24.9 520.2 0.0 3.2 192.9 0.6 183.0 39.1 5.5 0.0 28.7 0.7 3.4 0.0 31.1 0.0 15.6 0.1 1.7 0.0 0.0 0.0 9.7 201.8 1.6 12.2 0.6 1.3 0.0 0.0 0.1 7.1 0.0 0.0 1.3 16.2 0.0 14.7 0.0 0.0 1.3 10.6 0.0 0.0 0.0 0.0 0.0 0.0 28.3 3.5 0.0 6.2 1.3 18.3 0.0 163.8 0.0 0.0 0.0 7.0 0.0 0.0 132.5 47.2 36.8 0.6 0.1 1.7 31.5 SYT9 ENSG00000170743 "Synaptotagmin 9" Q86SS6 11 7238778-7469043 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9;retina: 7.6" "Cell type enhanced" "Detected in some" "Astrocytes: 48.6;Late spermatids: 23.5;Oligodendrocyte precursor cells: 55.3;Oligodendrocytes: 139.2" "Cancer enhanced" "Detected in some" "breast cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEK 293: 10.3;RT4: 17.9;SH-SY5Y: 13.2;TIME: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.47e-1)" "unprognostic (9.41e-2)" "unprognostic (1.39e-5)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (5.50e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.67e-2)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (3.31e-3)" "unprognostic (4.35e-2)" "unprognostic (1.92e-4)" "unprognostic (1.22e-4)" 0.0 2.0 9.1 0.0 9.2 0.0 0.8 11.7 5.9 0.4 1.4 0.1 0.0 1.2 0.0 0.0 0.1 0.1 0.3 4.7 7.6 2.0 3.6 0.0 0.0 9.9 11.8 0.1 1.3 0.9 1.5 0.0 9.6 1.0 0.0 7.6 0.0 3.6 0.0 0.1 0.1 0.1 8.1 0.0 0.1 0.9 15.9 0.0 1.1 0.0 0.0 0.2 0.3 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.5 0.0 0.0 0.0 0.0 17.9 3.2 13.2 0.0 0.0 0.0 0.4 0.0 0.0 20.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 9.2 11.7 5.9 4.7 7.6 9.9 11.8 9.6 8.1 15.9 11.7 0.0 0.0 0.0 48.6 0.5 0.0 0.1 0.0 0.0 13.6 0.7 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 13.9 0.0 0.2 0.0 0.0 0.0 15.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.2 0.0 3.3 9.8 0.0 0.0 0.3 0.0 23.5 0.0 0.0 0.0 5.6 0.0 2.0 0.0 55.3 139.2 0.0 0.0 0.0 0.0 0.2 0.0 1.5 0.0 3.5 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SYTL1 "exophilin-7, FLJ14996, JFC1, SLP1" ENSG00000142765 "Synaptotagmin like 1" Q8IYJ3 1 27342020-27353937 "Plasma proteins, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.9;pancreas: 106.3;skin 1: 87.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 158.8;NK-cells: 208.1;Squamous epithelial cells: 179.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 4.3;cerebellum: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 47.8;CAPAN-2: 55.8;NB-4: 81.8;U-266/70: 44.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA037825 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA037825: AB_10671635" "unprognostic (4.23e-2)" "unprognostic (8.23e-2)" "unprognostic (2.40e-1)" "prognostic favorable (6.83e-7)" "unprognostic (7.81e-3)" "unprognostic (5.81e-2)" "unprognostic (1.05e-1)" "unprognostic (7.18e-3)" "unprognostic (4.41e-1)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.45e-1)" "unprognostic (3.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-3)" 2.0 0.6 4.3 19.1 0.7 46.7 7.7 8.8 1.4 22.6 6.1 6.7 7.8 1.3 1.2 103.9 15.5 8.6 0.9 1.0 1.0 2.8 2.1 13.1 32.9 0.7 0.8 0.6 106.3 4.2 15.6 2.9 0.8 63.6 3.3 0.0 47.6 12.7 0.5 87.2 17.6 0.4 0.5 42.0 41.8 0.9 1.2 21.4 9.8 0.5 20.0 21.6 50.9 0.6 11.3 0.2 0.0 0.4 0.0 0.0 47.8 0.0 0.0 0.0 0.0 1.2 55.8 8.5 10.9 0.0 0.3 34.7 0.0 21.0 0.0 0.0 2.1 1.0 0.9 15.3 0.8 21.9 0.0 0.0 37.8 0.0 7.8 0.2 0.0 28.2 0.7 9.5 0.0 15.5 12.9 81.8 0.5 19.1 5.7 14.9 0.1 40.2 8.6 9.6 15.9 0.9 0.0 15.9 0.6 0.5 40.4 23.3 0.2 0.1 5.1 0.0 0.0 44.3 11.7 8.0 1.6 27.7 0.0 47.0 18.9 176.5 65.0 49.1 58.4 42.8 51.5 53.2 51.0 32.3 30.6 37.3 34.1 49.0 100.8 3.0 63.4 40.0 4.3 0.7 8.8 1.4 1.0 1.0 0.7 0.8 0.8 0.5 1.2 0.6 1.9 22.4 13.6 0.0 68.6 41.2 78.2 84.4 158.8 0.6 33.6 49.8 3.9 8.6 69.2 0.0 0.0 37.4 92.3 4.8 7.9 3.7 0.8 67.8 2.4 2.3 11.4 15.8 0.3 25.5 10.1 3.1 100.9 18.3 1.3 0.2 2.2 1.1 3.2 0.0 0.3 47.6 32.6 6.7 12.7 0.7 0.3 15.7 10.6 0.0 18.8 2.0 208.1 0.0 0.1 12.1 3.7 0.7 52.3 46.8 3.1 6.4 62.8 0.8 0.0 1.3 5.6 30.3 23.1 179.1 55.3 14.1 74.9 0.2 9.4 95.3 TACC2 "AZU-1, ECTACC" ENSG00000138162 "Transforming acidic coiled-coil containing protein 2" O95359 10 121989163-122254545 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 251.7;skeletal muscle: 387.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 210.1;Syncytiotrophoblasts: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031020, HPA031021, HPA061394" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 32000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA031020: AB_10669988, HPA031021: AB_2673701, HPA061394: AB_2684500" "unprognostic (3.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.75e-2)" "unprognostic (7.07e-2)" "unprognostic (2.26e-1)" "unprognostic (1.14e-1)" "unprognostic (9.15e-2)" "unprognostic (8.43e-3)" "unprognostic (1.14e-1)" "unprognostic (3.51e-1)" "unprognostic (2.13e-1)" "unprognostic (1.83e-2)" "prognostic favorable (2.50e-10)" "unprognostic (7.02e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (1.61e-1)" 22.1 15.3 18.2 5.3 18.6 0.2 20.9 23.6 22.7 32.3 28.6 91.5 15.3 26.1 9.2 64.2 32.9 12.9 251.7 19.1 18.8 33.9 18.8 68.7 1.0 16.0 16.9 8.8 25.3 36.4 58.7 21.6 14.8 67.7 20.7 7.2 60.7 13.5 387.1 103.3 35.7 22.0 11.8 4.2 49.1 5.8 16.9 5.7 50.7 159.0 5.7 62.4 49.1 17.7 17.8 55.1 26.5 15.2 7.4 7.4 31.7 7.7 20.7 10.5 7.3 22.7 28.9 0.0 7.0 12.3 12.1 58.1 8.5 20.9 10.9 3.0 4.4 0.0 7.7 43.8 11.5 0.0 0.3 3.4 86.0 5.6 36.6 8.6 22.2 0.1 4.5 0.6 10.4 23.5 0.2 9.9 15.7 27.6 24.8 0.3 15.2 8.5 28.9 26.9 17.6 14.2 12.7 52.0 29.5 7.6 10.2 0.4 20.6 4.7 3.5 11.8 14.5 2.4 11.7 0.3 8.7 0.1 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 18.6 23.6 22.7 19.1 18.8 16.0 16.9 14.8 11.8 16.9 17.7 15.5 83.3 94.1 16.3 0.7 33.6 49.7 54.3 33.0 21.6 23.4 14.1 210.1 8.6 70.7 36.8 0.0 53.3 0.4 75.2 1.9 8.2 2.4 88.4 11.0 21.3 30.0 0.0 32.8 14.2 4.4 21.2 38.7 62.8 7.0 0.1 6.1 18.9 6.5 43.7 48.2 38.8 57.0 0.3 4.3 2.6 6.8 1.9 7.2 7.5 0.1 1.1 0.0 80.9 7.6 19.4 47.1 7.5 0.2 49.6 36.5 13.5 84.9 2.7 13.1 27.2 23.7 0.5 8.2 79.5 54.0 228.5 2.6 2.8 41.9 80.5 TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 7 "Inhibitory neurons: 83.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA074573: AB_2686701" "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" 6.2 0.3 1.7 0.7 3.6 0.0 5.0 0.0 7.2 4.9 0.0 1.0 0.2 3.0 0.7 1.2 2.9 1.1 0.1 0.6 3.7 0.7 0.0 0.8 1.3 2.2 4.3 0.6 0.1 0.2 0.1 0.5 10.0 1.5 0.5 1.0 1.5 1.0 0.3 4.0 0.7 2.7 0.8 0.0 0.5 0.0 2.5 1.1 0.5 0.3 1.3 2.0 2.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.6 0.0 7.2 0.6 3.7 2.2 4.3 10.0 0.8 2.5 0.9 7.6 0.0 0.0 1.0 0.0 2.5 0.0 0.0 0.0 1.0 0.3 0.3 1.4 0.0 0.0 0.0 2.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 11.8 0.0 0.0 4.5 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 83.2 0.2 0.0 0.0 2.6 0.9 0.0 0.0 7.2 2.8 0.0 0.4 0.0 3.5 4.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 3.3 0.0 0.2 0.2 0.0 0.0 0.1 1.8 0.1 0.1 0.0 0.0 0.2 TAFA5 "FAM19A5, TAFA-5" ENSG00000219438 "TAFA chemokine like family member 5" Q7Z5A7 22 48489553-48850912 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 85.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Fibroblasts: 1.1" "Cancer enhanced" "Detected in all" "glioma: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 17.3;HEK 293: 13.6;Hep G2: 32.1;NTERA-2: 12.7;U-2 OS: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025629 Approved "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB025629: " "unprognostic (2.86e-1)" "unprognostic (2.98e-1)" "unprognostic (3.42e-2)" "unprognostic (2.19e-1)" "unprognostic (3.57e-1)" "unprognostic (1.80e-1)" "unprognostic (2.82e-3)" "unprognostic (2.41e-2)" "unprognostic (6.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-2)" "unprognostic (1.26e-1)" "unprognostic (9.31e-3)" "unprognostic (2.64e-2)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.94e-2)" 2.7 1.3 50.3 0.8 40.6 0.0 2.0 37.0 51.8 19.7 15.0 8.4 1.0 8.1 4.7 0.9 5.2 2.0 2.5 53.9 43.0 2.4 2.7 2.1 0.4 55.2 85.9 12.1 2.4 4.3 7.0 0.1 51.1 6.8 0.2 3.6 4.9 3.2 1.5 5.4 3.3 0.7 41.5 0.3 2.9 3.3 49.6 1.2 0.8 1.7 0.1 4.0 4.9 28.2 0.0 1.3 2.5 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 17.3 0.1 0.1 1.3 0.0 0.0 0.0 13.6 0.0 0.2 32.1 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.3 12.7 0.6 0.0 0.6 0.0 7.4 0.0 0.0 7.2 0.2 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 40.6 37.0 51.8 53.9 43.0 55.2 85.9 51.1 41.5 49.6 28.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBX22 "CLPA, CPX" ENSG00000122145 "T-box transcription factor 22" Q9Y458 X 80014753-80031774 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "testis: 11.1;thyroid gland: 4.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HDLM-2: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (6.58e-2)" "unprognostic (6.31e-2)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBX5 HOS ENSG00000089225 "T-box transcription factor 5" Q99593 12 114353911-114408442 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 88.1;lung: 20.8;placenta: 28.7" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 104.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 18.9;BJ hTERT+: 41.5;BJ hTERT+ SV40 Large T+: 9.2;BJ hTERT+ SV40 Large T+ RasG12V: 12.2;HAP1: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008786, HPA064683" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA008786: AB_10601720, HPA064683: AB_2685320" "unprognostic (3.09e-2)" "unprognostic (1.53e-1)" "unprognostic (3.79e-2)" "unprognostic (2.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-7)" "unprognostic (2.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.34e-2)" "unprognostic (4.38e-3)" 3.4 0.0 0.1 0.0 0.0 0.0 4.4 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 88.1 0.9 0.0 0.0 0.0 20.8 0.6 0.3 0.1 0.0 0.0 1.3 0.0 28.7 0.3 3.4 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 5.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 18.9 41.5 9.2 12.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 16.3 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.9 0.0 0.3 0.1 0.3 0.0 0.0 0.2 2.9 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.0 4.5 0.1 0.1 104.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 7.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 TCEAL6 WEX2 ENSG00000204071 "Transcription elongation factor A like 6" Q6IPX3 X 102140476-102142970 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.4;pituitary gland: 73.4;testis: 26.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 40.4;Excitatory neurons: 9.1;Horizontal cells: 15.2;Inhibitory neurons: 10.4;Late spermatids: 6.7" "Cancer enriched" "Detected in single" 9 "glioma: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045564, HPA058982" Supported Uncertain Nucleoplasm NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA045564: AB_2679369, HPA058982: AB_2683870" "unprognostic (5.43e-2)" "unprognostic (6.54e-2)" "unprognostic (1.87e-3)" "unprognostic (6.69e-3)" "unprognostic (1.39e-1)" "unprognostic (2.69e-2)" "unprognostic (1.88e-2)" "unprognostic (3.89e-2)" "unprognostic (1.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.33e-2)" "unprognostic (1.18e-1)" 1.6 10.7 27.3 0.2 24.3 0.0 0.6 23.1 41.4 1.5 3.6 1.7 0.2 3.6 1.4 0.0 5.7 0.1 0.5 23.8 35.4 1.0 0.0 0.1 0.0 27.3 32.9 8.5 0.4 1.8 73.4 0.0 26.3 0.8 0.2 16.7 1.8 0.6 0.0 0.3 0.7 0.7 19.2 0.0 0.8 26.8 26.0 0.0 0.5 0.2 0.0 0.0 1.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 27.3 24.3 23.1 41.4 23.8 35.4 27.3 32.9 26.3 19.2 26.0 22.5 0.0 0.0 0.0 3.9 0.0 0.1 0.5 0.0 0.0 40.4 0.0 0.1 4.6 0.0 0.0 3.7 2.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.0 9.1 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.1 15.2 10.4 0.0 0.0 0.0 0.3 6.7 2.5 0.1 1.8 1.0 0.0 1.9 0.0 4.5 1.7 0.4 0.0 0.7 0.0 0.5 0.0 0.0 0.0 4.3 0.0 1.4 0.9 1.9 0.9 0.0 0.3 0.0 0.2 0.0 0.0 0.1 TCF20 "AR1, SPBP" ENSG00000100207 "Transcription factor 20" Q9UGU0 22 42160013-42343616 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 127.0;Inhibitory neurons: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017849, HPA036786" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "CAB017849: , HPA036786: AB_2675313" "unprognostic (2.17e-1)" "unprognostic (2.12e-2)" "prognostic favorable (1.88e-4)" "unprognostic (2.19e-2)" "unprognostic (1.19e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (4.89e-4)" "unprognostic (1.77e-1)" "unprognostic (2.36e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-3)" "unprognostic (7.30e-2)" "unprognostic (1.17e-3)" "unprognostic (3.07e-3)" "unprognostic (4.94e-1)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" 7.1 6.5 4.2 1.7 3.1 1.6 7.5 0.0 2.9 10.2 0.0 9.1 1.6 9.0 0.2 16.3 6.9 1.0 4.9 3.7 2.4 7.6 7.4 7.1 1.6 0.9 1.0 7.6 8.2 1.2 7.4 1.2 1.1 6.9 1.3 0.9 9.9 1.0 5.7 14.3 10.0 1.4 0.0 7.3 8.0 15.3 1.8 2.3 9.6 1.3 1.6 7.8 11.0 2.1 6.6 2.3 3.2 2.1 1.0 2.1 5.5 4.2 2.8 2.1 3.5 5.0 2.5 10.9 3.6 1.1 3.1 5.4 3.9 3.3 1.2 8.5 3.9 3.4 2.2 1.6 1.5 6.0 4.7 1.2 2.9 3.0 3.0 0.9 1.0 3.1 4.1 3.9 1.6 3.0 9.4 1.8 3.4 2.2 3.1 4.7 2.0 5.7 0.5 5.2 6.2 2.0 2.7 2.0 2.7 2.0 1.2 4.8 3.9 3.8 8.9 3.9 1.9 7.0 6.2 4.5 2.3 4.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.1 0.0 2.9 3.7 2.4 0.9 1.0 1.1 0.0 1.8 2.1 10.0 0.0 9.6 23.5 9.1 22.6 11.3 19.4 12.0 25.1 11.5 6.9 7.3 17.2 10.1 9.2 18.8 6.3 11.0 16.6 0.0 10.8 127.0 14.2 9.9 9.3 16.8 9.9 54.0 7.5 5.5 8.1 10.7 22.2 1.3 10.0 8.9 12.6 6.2 10.1 63.5 13.8 12.2 12.4 13.3 36.2 12.5 9.4 7.2 22.5 12.0 5.6 6.2 29.7 55.0 13.3 13.5 6.4 8.7 20.9 13.0 6.0 13.4 12.6 6.6 5.8 8.5 19.1 13.4 19.5 22.9 4.5 13.0 4.3 17.9 14.6 TCHH THH ENSG00000159450 Trichohyalin Q07283 1 152106317-152115454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 41.4" "Cell type enhanced" "Detected in some" "Kupffer cells: 26.2;Langerhans cells: 9.5;Macrophages: 21.8;Spermatocytes: 22.6;Spermatogonia: 29.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.6;SCLC-21H: 1.1;THP-1: 2.0" "Low region specificity" "Detected in many" HPA028375 Approved NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "HPA028375: AB_10601722" "unprognostic (7.70e-3)" "unprognostic (3.84e-2)" "unprognostic (1.14e-3)" "unprognostic (1.14e-1)" "unprognostic (2.07e-1)" "unprognostic (2.30e-2)" "unprognostic (4.97e-3)" "unprognostic (2.15e-2)" "unprognostic (1.84e-2)" "unprognostic (7.12e-5)" "unprognostic (2.03e-1)" "unprognostic (6.55e-2)" "unprognostic (5.90e-6)" "unprognostic (5.58e-2)" "unprognostic (1.12e-1)" "unprognostic (9.71e-2)" "unprognostic (9.28e-7)" 0.7 0.1 0.1 0.1 0.1 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.3 0.2 0.0 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 41.4 0.2 0.0 0.0 2.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.7 0.0 0.0 3.6 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.1 1.0 0.1 0.1 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.9 0.2 0.1 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.5 6.4 0.1 0.5 2.8 0.5 1.2 2.5 2.0 0.0 0.3 1.8 0.0 0.6 0.0 0.3 0.0 0.0 0.2 1.4 0.2 3.5 1.8 0.0 0.5 0.2 7.5 0.9 0.0 0.8 0.0 0.1 2.5 0.0 0.6 0.0 0.5 0.5 0.0 26.2 9.5 0.2 0.3 21.8 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 1.3 0.0 0.0 0.7 0.0 0.0 3.2 1.4 22.6 29.1 1.0 2.4 5.2 0.8 0.1 0.0 0.1 TCIRG1 "a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7" ENSG00000110719 "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3" Q13488 11 68039025-68050895 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 289.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 135.5;Kupffer cells: 115.2;Macrophages: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 131.9;RPMI-8226: 138.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038742 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA038742: AB_10795138" "unprognostic (5.35e-2)" "unprognostic (5.01e-2)" "unprognostic (1.81e-2)" "unprognostic (1.50e-2)" "unprognostic (6.98e-3)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "unprognostic (2.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.50e-11)" "unprognostic (2.48e-3)" "unprognostic (7.88e-3)" "unprognostic (2.50e-1)" "prognostic favorable (9.45e-6)" 56.8 112.5 7.1 46.1 7.1 97.7 47.2 9.2 14.5 85.1 11.4 66.6 44.2 58.0 18.6 45.3 61.4 11.7 27.9 6.6 7.2 35.5 61.7 113.9 30.9 10.9 9.3 49.1 289.2 4.4 20.3 14.1 12.0 72.2 8.0 0.3 57.9 16.1 10.5 25.9 87.0 12.1 9.1 194.8 59.2 6.7 18.1 12.1 52.5 3.9 13.4 56.1 60.7 10.8 31.8 57.2 0.8 0.2 25.1 19.7 39.0 61.5 29.4 17.2 16.3 1.3 92.0 2.7 32.9 21.9 26.2 39.0 3.7 23.5 3.6 82.1 1.9 22.0 80.6 18.9 23.4 16.3 131.9 22.8 13.5 21.2 1.4 0.0 11.8 1.2 11.6 8.4 5.7 10.7 0.8 97.8 3.5 44.6 14.4 26.8 0.9 138.6 16.2 17.6 3.0 0.7 26.0 33.4 16.8 6.1 36.3 41.1 42.3 33.2 25.9 93.3 11.4 1.3 1.2 4.8 74.0 26.7 16.2 21.7 65.5 72.8 15.7 109.0 12.7 11.3 11.7 16.9 49.0 7.5 6.6 7.2 150.0 32.1 144.3 33.8 12.1 47.8 7.1 7.1 9.2 14.5 6.6 7.2 10.9 9.3 12.0 9.1 18.1 10.8 40.6 28.9 59.8 0.3 37.1 6.2 13.2 36.2 7.4 0.7 14.9 8.9 1.6 18.6 57.1 7.3 0.0 21.7 60.6 74.2 0.0 30.4 0.4 13.3 16.7 22.1 23.9 15.2 0.3 67.0 54.1 24.9 135.5 21.5 50.0 29.5 21.0 17.8 105.1 0.0 0.6 32.4 18.3 115.2 22.8 0.6 5.9 132.3 5.4 8.4 74.9 0.7 45.3 0.5 0.1 51.8 85.4 13.2 59.1 10.6 45.5 2.0 47.9 1.0 39.5 7.7 26.0 0.1 2.9 10.4 5.3 26.5 46.5 9.0 36.2 19.0 TCN2 "D22S676, D22S750, TC2" ENSG00000185339 "Transcobalamin 2" P20062 22 30607003-30627271 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Hepatic stellate cells: 137.4;Kupffer cells: 144.1;Proximal enterocytes: 563.6;Proximal tubular cells: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 43.8;intermediate monocyte: 66.5;non-classical monocyte: 24.4" "Lineage enriched" "Detected in many" 8 "monocytes: 66.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 117.6;HUVEC TERT2: 142.6;Karpas-707: 184.0;RPTEC TERT1: 70.7;TIME: 85.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000837 Approved Cytosol "Secreted to blood" NA NA 19000000 "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA000837: AB_1080235" "unprognostic (6.43e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.53e-3)" "unprognostic (3.17e-1)" "unprognostic (1.49e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.64e-4)" "unprognostic (1.52e-2)" "unprognostic (2.90e-1)" "unprognostic (1.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.59e-1)" "unprognostic (6.95e-3)" "unprognostic (4.94e-3)" "unprognostic (2.09e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" 49.6 30.6 24.6 16.0 24.1 5.5 37.9 25.5 30.6 25.9 27.1 23.4 23.6 28.7 20.3 8.6 21.5 50.1 28.7 22.7 25.3 115.8 17.3 37.7 35.3 27.1 26.1 14.8 12.1 8.6 15.1 18.6 27.7 16.0 27.8 11.1 13.2 45.4 6.0 9.0 59.5 36.8 25.5 46.7 17.4 21.9 29.7 6.4 26.4 13.7 10.0 22.0 14.7 25.3 0.2 9.5 41.8 0.2 24.6 117.6 1.4 3.1 30.9 8.0 13.1 4.6 21.2 0.6 45.7 6.2 0.7 1.5 3.7 2.2 2.5 0.0 2.3 0.2 1.2 2.0 58.5 0.6 33.7 19.8 2.5 6.1 5.1 8.8 142.6 0.0 0.8 184.0 12.7 0.1 0.1 3.3 16.4 11.7 1.0 4.9 6.0 64.2 70.7 1.1 14.4 1.9 0.3 0.6 12.0 2.8 0.4 2.0 85.3 26.4 3.5 3.3 1.3 5.1 1.4 0.2 9.5 1.7 0.6 0.0 43.8 0.0 0.1 66.5 0.7 0.0 0.8 0.4 7.9 0.0 0.3 0.6 1.4 0.0 24.4 1.5 0.2 18.8 24.6 24.1 25.5 30.6 22.7 25.3 27.1 26.1 27.7 25.5 29.7 25.3 105.0 3.2 3.9 3.9 3.7 5.2 2.2 4.7 0.6 8.0 7.1 5.1 6.5 27.1 13.7 12.9 20.9 0.4 0.5 70.9 7.9 7.8 1.1 3.5 5.4 64.6 6.7 0.8 0.2 6.0 0.8 19.5 5.1 6.2 4.5 23.4 137.4 5.6 45.9 1.7 1.9 28.6 4.1 144.1 9.4 1.4 10.5 53.8 23.2 8.4 8.8 7.4 0.0 5.5 1.7 5.1 50.2 9.8 13.5 2.0 563.6 125.8 2.8 29.1 13.1 0.9 5.5 1.0 12.6 0.5 5.3 0.4 2.2 5.6 21.0 2.7 TDRD10 DKFZp434M202 ENSG00000163239 "Tudor domain containing 10" Q5VZ19 1 154502219-154548147 "Cancer-related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 55.6" "Group enriched" "Detected in some" 5 "Early spermatids: 61.8;Late spermatids: 89.0;Spermatocytes: 103.7" "Cancer enhanced" "Detected in many" "testis cancer: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.0;TIME: 1.4" "Not detected" "Not detected" HPA054327 Approved Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA054327: AB_2682452" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.33e-3)" "unprognostic (9.69e-3)" "unprognostic (5.80e-3)" "unprognostic (2.99e-1)" "unprognostic (5.97e-3)" "unprognostic (2.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.00e-3)" "unprognostic (1.61e-1)" "unprognostic (1.34e-3)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "prognostic favorable (8.04e-5)" "unprognostic (1.62e-1)" 11.1 4.5 3.7 0.5 3.7 0.1 6.8 3.1 3.7 5.1 3.3 2.8 0.7 4.2 2.3 2.4 6.5 1.6 7.6 3.3 3.2 3.5 4.5 8.1 0.8 3.2 3.5 10.1 0.9 0.9 2.6 1.7 3.3 3.9 1.3 0.1 1.8 1.2 1.9 2.3 3.5 1.8 3.2 8.9 1.9 55.6 3.7 0.5 11.0 1.4 0.4 3.9 3.6 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.7 3.1 3.7 3.3 3.2 3.2 3.5 3.3 3.2 3.7 3.1 10.0 3.2 6.7 4.9 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.5 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.8 0.0 0.1 8.2 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 1.3 0.7 6.1 0.4 0.4 0.0 0.5 0.0 0.0 4.0 2.1 89.0 2.5 1.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 103.7 16.5 0.1 0.3 0.0 0.0 0.1 0.0 0.0 TEAD2 "ETF, TEF-4, TEF4" ENSG00000074219 "TEA domain transcription factor 2" Q15562 19 49340595-49362457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 51.1;Early spermatids: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 1.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 27 "B-cells: 2.7" "Cell line enhanced" "Detected in many" "AF22: 135.3;AN3-CA: 147.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066292, HPA069963" Supported Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA066292: AB_2685651, HPA069963: AB_2686222" "unprognostic (2.69e-2)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (1.03e-2)" "unprognostic (8.58e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (8.66e-4)" "unprognostic (2.91e-1)" "unprognostic (4.47e-3)" "unprognostic (1.11e-1)" "unprognostic (3.96e-3)" "unprognostic (1.24e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-1)" "unprognostic (6.78e-2)" 32.8 17.8 7.5 15.4 7.1 0.2 31.6 6.6 7.9 41.8 16.2 50.4 7.6 39.6 12.4 11.0 34.2 15.5 55.5 7.5 6.8 34.5 11.9 35.7 9.0 8.7 8.3 33.5 26.8 19.4 9.2 17.7 7.7 26.5 11.2 3.4 18.5 22.7 12.9 10.7 18.5 38.4 7.6 14.8 31.3 26.6 8.3 3.1 16.9 22.1 7.3 27.2 24.4 6.6 12.5 28.6 135.3 147.6 14.2 20.8 24.3 22.8 23.9 25.6 29.7 2.3 6.8 1.2 29.6 38.5 13.1 13.9 37.5 7.7 14.1 0.1 17.5 0.0 27.2 19.3 24.6 0.1 0.3 24.8 17.8 17.4 8.4 50.6 92.1 0.1 22.0 0.0 36.1 15.3 0.0 0.2 45.4 35.2 36.2 0.0 40.8 0.2 23.3 0.2 0.2 82.0 38.1 5.6 10.1 46.1 40.5 3.5 55.0 45.9 28.1 9.9 1.8 0.1 0.1 4.8 1.7 0.6 18.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 7.1 6.6 7.9 7.5 6.8 8.7 8.3 7.7 7.6 8.3 6.6 26.1 3.2 3.2 0.0 3.8 3.3 6.9 5.9 8.6 0.4 21.1 9.5 1.0 8.6 3.4 12.9 0.0 0.6 0.4 1.3 1.9 51.1 76.6 7.3 20.7 29.5 7.1 3.2 0.1 26.2 23.7 15.0 9.7 6.5 0.0 14.7 21.4 2.8 0.6 0.0 0.1 6.6 8.2 0.9 3.6 29.6 15.2 0.7 5.4 1.9 0.0 15.9 0.0 0.0 0.1 22.7 4.9 22.2 0.1 7.2 0.1 0.2 1.2 0.4 32.9 7.6 28.7 2.1 2.4 2.0 1.6 1.2 0.5 4.4 6.8 2.8 TENM2 "KIAA1127, ODZ2, Ten-M2, TEN2" ENSG00000145934 "Teneurin transmembrane protein 2" Q9NT68 5 167284799-168264157 "Predicted membrane proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 9.8;heart muscle: 35.1" "Group enriched" "Detected in many" 5 "Astrocytes: 512.9;Excitatory neurons: 706.2;Inhibitory neurons: 965.9" "Cancer enriched" "Detected in many" 6 "head and neck cancer: 15.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 66.1;HBEC3-KT: 43.0;HDLM-2: 43.3;U-138 MG: 74.6;U-2 OS: 64.0;U-251 MG: 50.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038018, HPA038420, HPA068691" Uncertain Approved Nucleoli No No 11000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "HPA038018: , HPA038420: AB_10674682, HPA068691: AB_2686019" "unprognostic (6.00e-2)" "unprognostic (1.50e-1)" "unprognostic (2.94e-2)" "unprognostic (9.16e-3)" "unprognostic (3.88e-3)" "unprognostic (3.81e-3)" "unprognostic (5.81e-2)" "unprognostic (2.41e-1)" "unprognostic (4.62e-2)" "unprognostic (2.10e-2)" "unprognostic (3.68e-3)" "unprognostic (4.34e-2)" "unprognostic (4.69e-5)" "unprognostic (3.47e-2)" "unprognostic (1.03e-1)" "unprognostic (5.16e-4)" "prognostic unfavorable (7.52e-4)" 0.1 0.5 2.9 0.0 4.7 0.0 1.9 0.0 9.8 1.3 0.0 0.2 0.4 0.0 0.5 1.9 0.1 0.4 35.1 6.0 1.2 0.8 1.3 0.2 0.0 0.6 0.1 0.7 0.1 0.0 0.7 0.0 1.6 2.2 0.1 4.1 0.5 1.0 0.0 3.2 0.2 0.0 0.0 0.0 0.1 1.3 4.3 2.2 0.4 0.5 1.0 0.1 2.0 0.0 0.1 0.0 13.4 0.0 0.0 0.4 0.0 1.9 0.0 0.7 1.8 0.0 0.0 0.0 0.0 66.1 1.7 0.0 0.0 43.0 0.8 43.3 0.0 0.0 0.2 0.0 2.0 0.0 0.0 3.0 7.4 0.3 5.3 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.3 9.8 0.2 0.0 0.0 6.6 0.0 0.1 0.0 0.1 2.4 3.8 0.1 0.0 74.6 64.0 0.1 50.0 0.0 0.0 0.0 7.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 4.7 0.0 9.8 6.0 1.2 0.6 0.1 1.6 0.0 4.3 0.0 0.5 0.0 0.0 512.9 0.0 14.8 1.1 20.3 33.6 15.5 0.3 13.0 144.0 0.0 1.4 0.0 18.8 0.0 0.0 1.0 0.0 3.4 23.5 0.1 0.3 1.7 0.0 0.0 706.2 0.2 0.0 2.2 0.0 0.2 1.3 1.6 0.4 5.1 0.1 121.1 965.9 0.7 0.0 0.0 1.2 18.2 4.4 0.2 1.8 36.5 0.0 2.3 0.0 21.6 12.8 0.0 0.0 61.7 0.0 1.4 0.3 0.0 0.6 1.8 0.0 0.4 1.5 1.2 1.1 1.4 1.7 0.0 0.1 0.0 0.4 0.1 TESC "CHP3, FLJ20607, TSC" ENSG00000088992 Tescalcin Q96BS2 12 117038923-117099479 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 329.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 183.0;Erythroid cells: 222.9;Exocrine glandular cells: 481.2;Gastric mucus-secreting cells: 316.0;Late spermatids: 319.3;Pancreatic endocrine cells: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 261.1" "Lineage enriched" "Detected in all" 5 "monocytes: 261.1" "Cell line enhanced" "Detected in many" "HMC-1: 398.5;NB-4: 675.1;OE19: 288.1;U-937: 221.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053200 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm Cytosol "HPA053200: AB_2682079" "unprognostic (4.53e-3)" "unprognostic (5.98e-2)" "unprognostic (6.50e-2)" "unprognostic (2.23e-3)" "unprognostic (6.31e-2)" "unprognostic (2.05e-3)" "unprognostic (4.98e-3)" "unprognostic (3.35e-1)" "unprognostic (4.35e-1)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.69e-2)" "unprognostic (8.65e-2)" "unprognostic (2.57e-1)" "unprognostic (1.56e-2)" "unprognostic (5.67e-3)" 8.1 46.5 17.4 10.3 36.8 118.8 8.9 16.4 25.4 4.3 15.7 3.8 7.2 3.9 121.9 3.3 4.0 36.1 71.5 26.5 15.0 26.5 4.9 10.2 8.0 17.8 15.0 5.3 102.4 9.4 26.7 10.2 18.2 9.8 2.8 0.5 329.9 19.7 5.1 9.7 7.3 2.8 14.8 11.9 138.4 31.1 15.5 7.4 10.7 8.1 10.3 29.3 5.3 18.9 0.2 97.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 4.3 13.8 4.7 0.0 0.2 0.6 8.1 0.0 0.0 37.5 19.2 115.5 9.8 78.1 0.0 49.2 398.5 0.1 0.0 0.0 0.0 0.0 0.0 18.5 54.0 0.9 0.0 2.2 95.5 675.1 9.0 288.1 0.0 0.4 0.0 52.4 56.5 15.0 17.0 6.1 0.1 0.1 3.6 0.9 0.0 53.9 0.0 0.0 1.7 0.2 0.4 17.0 38.2 0.0 0.1 221.8 0.5 0.0 51.0 51.5 7.0 67.9 0.4 5.5 2.4 9.1 35.8 13.1 0.3 3.8 12.6 11.6 261.1 2.6 3.5 19.0 17.4 36.8 16.4 25.4 26.5 15.0 17.8 15.0 18.2 14.8 15.5 18.9 35.6 0.0 0.0 5.9 16.2 2.7 0.3 0.4 1.8 0.8 5.5 67.1 58.3 183.0 0.9 12.9 0.0 0.4 21.1 0.2 74.3 159.5 106.5 1.3 0.7 43.6 1.8 222.9 26.1 481.2 0.6 7.9 316.0 3.2 71.1 1.2 1.8 0.5 48.0 0.0 2.0 1.5 0.0 17.9 6.1 319.3 3.1 30.6 72.9 8.4 41.0 0.2 25.7 2.5 1.5 215.6 0.9 3.4 25.8 3.5 0.2 6.1 0.0 1.5 144.7 1.9 68.4 63.0 20.3 0.5 2.0 1.2 28.3 66.7 2.3 1.3 TFDP1 "DILC, Dp-1, DP1, DRTF1" ENSG00000198176 "Transcription factor Dp-1" Q14186 13 113584721-113641473 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 164.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 344.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 31.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 31.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033605, HPA044754, HPA068909, HPA077304" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "Nuclear membrane, Cytosol" "CAB033605: AB_783105, HPA044754: AB_2679074, HPA068909: AB_2686056, HPA077304: " "unprognostic (4.28e-2)" "unprognostic (9.50e-3)" "unprognostic (1.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.01e-2)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (5.50e-3)" "unprognostic (1.68e-2)" "unprognostic (3.96e-1)" "unprognostic (2.04e-2)" "unprognostic (2.43e-2)" "prognostic favorable (7.57e-4)" "prognostic favorable (6.17e-4)" "unprognostic (2.30e-1)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" 28.2 23.5 24.3 38.6 24.0 164.0 27.2 24.5 24.4 33.5 32.5 37.8 30.5 27.6 19.4 50.1 32.8 24.6 34.3 24.1 22.8 23.2 25.9 21.8 67.1 27.5 24.4 19.3 18.4 28.5 21.3 40.6 25.3 26.1 42.4 20.2 26.1 30.8 58.2 42.8 32.3 34.3 26.6 30.8 31.3 49.6 26.8 53.4 33.1 59.0 68.3 37.5 30.1 25.7 343.2 82.5 104.4 89.5 138.4 122.7 118.5 187.8 168.7 238.1 218.6 173.3 155.9 314.6 61.3 181.3 130.3 160.3 183.0 167.1 232.2 215.9 212.8 184.4 129.2 109.8 86.8 468.3 155.7 102.1 147.3 151.3 87.4 85.0 162.7 116.2 154.1 82.6 215.5 117.7 207.0 181.4 96.6 322.7 105.0 138.9 93.0 181.1 91.3 129.1 268.2 79.3 84.8 228.8 58.7 75.1 157.9 371.7 114.4 77.2 122.9 165.6 210.8 69.5 92.4 326.4 171.9 285.2 133.2 31.9 3.0 4.6 3.1 3.8 3.4 4.4 4.1 3.7 5.9 3.6 6.3 3.2 3.8 2.3 5.5 3.0 5.3 2.5 24.3 24.0 24.5 24.4 24.1 22.8 27.5 24.4 25.3 26.6 26.8 25.7 21.4 9.6 15.8 12.7 38.8 59.8 32.1 16.1 33.6 10.3 45.6 35.2 26.6 28.6 14.7 29.5 14.6 83.2 33.8 29.8 80.3 12.3 5.5 34.4 28.2 25.8 40.2 344.3 22.5 11.9 128.0 30.8 38.7 31.0 21.0 23.3 34.6 58.7 49.2 6.7 19.5 36.1 12.2 49.1 51.2 10.7 28.6 41.1 35.6 5.6 24.8 14.7 16.5 9.5 10.2 19.0 24.2 28.2 67.3 35.7 29.4 66.5 21.0 22.5 6.6 20.0 32.7 76.7 52.7 74.6 60.0 66.6 32.1 30.3 47.4 35.8 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 713.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Basal respiratory cells: 63.6;Club cells: 18.8;Distal tubular cells: 29.4;Squamous epithelial cells: 34.7" "Group enriched" "Detected in many" 4 "cervical cancer: 30.8;head and neck cancer: 78.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.5;HaCaT: 24.2;HeLa: 16.2;MCF7: 17.5;SK-BR-3: 21.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171, HPA070372" Enhanced Approved "Vesicles,Plasma membrane" NA NA 530000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB015159: AB_2202870, HPA040171: AB_2676869, HPA070372: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 25.7 1.3 0.6 0.9 0.8 0.7 2.2 3.7 2.0 78.7 0.8 1.4 0.8 1.0 1.6 713.5 4.4 0.6 5.1 0.5 0.6 2.5 1.7 5.3 1.5 1.5 0.9 3.0 3.2 0.2 3.3 1.2 1.4 4.1 0.9 1.7 89.7 4.4 1.1 73.2 1.9 0.5 0.4 2.6 1.8 2.9 0.9 1.3 2.7 0.3 40.4 1.3 144.2 0.9 1.1 2.0 1.1 1.0 0.0 0.8 17.5 0.4 0.2 1.0 1.6 1.2 1.7 1.0 2.3 1.3 0.3 24.2 2.8 2.0 0.6 2.0 3.3 1.4 16.2 5.7 0.8 0.9 1.5 1.5 9.3 0.5 2.0 0.5 0.7 3.4 1.0 1.0 0.7 17.5 0.7 1.9 0.3 1.1 2.2 1.1 0.1 1.1 0.6 2.1 1.2 1.6 0.2 21.7 0.1 1.4 1.5 1.1 0.8 1.1 4.8 2.0 0.9 1.5 1.8 0.3 0.4 2.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 3.7 2.0 0.5 0.6 1.5 0.9 1.4 0.4 0.9 0.9 0.2 12.8 1.1 2.0 0.0 0.3 4.6 63.6 4.0 0.9 1.1 0.8 0.8 5.7 18.8 0.0 0.0 1.4 0.3 0.2 29.4 2.0 0.1 0.3 0.2 0.2 0.0 0.0 1.5 0.9 0.8 3.9 0.0 0.6 4.5 0.7 0.0 0.2 0.4 0.0 1.7 0.1 6.1 0.6 0.3 0.0 0.6 0.4 0.0 1.0 0.4 0.2 0.0 1.0 1.0 2.6 0.0 0.4 0.1 7.4 0.1 0.2 2.1 0.6 0.0 0.1 1.0 0.0 0.6 34.7 1.8 1.2 0.6 1.2 0.3 6.2 THAP11 "CTG-B43a, CTG-B45d, HRIHFB2206, RONIN" ENSG00000168286 "THAP domain containing 11" Q96EK4 16 67842320-67844195 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041434, HPA042189, HPA072537" Supported Supported Nucleoplasm,Cytosol NA No "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Nucleoplasm Cytosol "HPA041434: AB_10960385, HPA042189: AB_10964636, HPA072537: " "unprognostic (1.43e-1)" "unprognostic (2.51e-1)" "unprognostic (2.82e-1)" "unprognostic (1.54e-3)" "unprognostic (1.93e-3)" "unprognostic (1.40e-2)" "unprognostic (1.56e-3)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (2.34e-1)" "unprognostic (1.66e-1)" "unprognostic (9.51e-2)" "unprognostic (2.97e-1)" "unprognostic (2.11e-1)" "unprognostic (2.10e-2)" "unprognostic (4.59e-2)" "unprognostic (5.87e-2)" 16.6 14.4 20.5 14.9 21.1 10.2 16.3 21.4 21.3 21.9 19.2 26.7 12.3 24.5 13.0 19.5 22.4 10.1 25.1 20.7 21.7 16.1 14.9 15.4 20.8 22.1 20.8 20.9 19.3 16.9 16.4 12.3 20.6 16.1 11.1 10.9 15.7 19.6 48.1 26.1 22.1 17.2 22.5 24.8 20.8 12.6 21.1 23.5 14.9 26.4 19.0 23.9 18.4 23.1 31.3 40.2 27.4 25.9 37.5 25.7 28.7 15.5 27.0 37.1 31.9 51.9 23.6 68.0 31.7 15.9 22.3 35.6 48.6 29.0 21.1 25.4 55.3 27.1 22.5 64.1 34.2 34.9 29.4 23.6 28.4 25.6 22.4 26.8 27.7 45.9 39.5 15.4 22.9 49.1 37.7 62.6 55.1 36.9 34.7 73.6 32.7 61.4 19.0 20.2 38.2 43.1 45.4 16.4 33.2 19.6 40.1 35.2 22.3 23.4 28.4 21.3 19.2 60.9 65.9 67.5 18.3 38.2 25.8 7.6 13.6 14.7 26.3 18.4 20.7 13.8 23.6 24.2 14.3 18.8 29.9 24.0 4.1 21.3 17.5 11.3 31.5 17.9 20.5 21.1 21.4 21.3 20.7 21.7 22.1 20.8 20.6 22.5 21.1 23.1 20.4 22.4 13.1 3.3 24.4 29.2 25.0 6.6 22.8 25.6 27.4 23.6 15.1 12.8 5.3 11.0 4.2 19.6 32.8 12.5 52.8 7.6 1.2 18.6 18.0 21.3 13.2 23.8 4.6 9.5 25.9 17.4 7.1 14.3 7.6 20.3 24.3 14.0 22.4 8.4 4.6 16.2 6.1 19.6 20.0 2.2 23.6 19.1 10.6 4.7 24.5 29.8 43.3 7.1 6.1 6.5 5.9 31.2 18.9 25.0 13.5 19.8 6.1 16.9 19.7 24.2 22.2 16.1 27.4 20.9 39.1 13.5 32.5 28.6 16.5 20.2 THAP8 FLJ32891 ENSG00000161277 "THAP domain containing 8" Q8NA92 19 36034984-36054739 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 18.8;Spermatogonia: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA064056, HPA070139" Approved Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA064056: AB_2685184, HPA070139: AB_2686230" "unprognostic (1.33e-3)" "unprognostic (2.24e-1)" "unprognostic (8.03e-2)" "unprognostic (1.08e-2)" "unprognostic (3.10e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (9.01e-3)" "unprognostic (3.94e-1)" "unprognostic (1.27e-1)" "prognostic favorable (3.19e-4)" "unprognostic (2.50e-1)" "unprognostic (2.10e-2)" "unprognostic (9.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.48e-2)" "unprognostic (2.48e-1)" 3.3 3.2 9.1 2.5 9.8 0.9 2.7 9.4 9.6 5.0 6.3 9.5 3.7 4.7 3.4 3.7 3.8 3.5 3.5 8.3 9.7 4.1 4.6 2.8 3.1 10.1 9.8 3.5 2.8 3.7 3.4 2.8 10.2 3.6 2.4 4.6 3.0 4.3 10.2 5.2 3.5 4.4 8.9 3.4 3.6 9.7 9.7 4.0 3.1 3.3 2.2 6.6 4.0 11.2 3.3 8.2 4.4 3.7 11.6 8.0 2.8 2.7 4.8 5.5 7.8 3.6 2.3 4.5 9.7 4.5 5.7 1.5 2.5 3.3 2.1 3.2 1.6 2.8 3.0 4.3 12.7 1.6 2.7 6.2 5.0 3.8 2.6 6.2 2.6 8.2 2.4 5.3 5.8 5.5 4.1 3.4 3.9 5.6 3.1 3.9 1.4 4.2 4.5 2.9 8.1 6.1 4.6 3.9 3.3 5.7 4.1 2.2 2.3 7.3 4.5 4.5 2.2 5.2 4.5 3.3 8.0 2.6 4.7 7.1 6.5 7.9 5.2 7.6 5.9 4.1 5.5 5.4 4.7 3.0 4.1 6.1 2.7 6.2 6.6 4.5 5.8 4.1 9.1 9.8 9.4 9.6 8.3 9.7 10.1 9.8 10.2 8.9 9.7 11.2 1.4 3.2 3.7 3.6 3.4 1.1 1.2 3.2 2.8 2.2 3.0 2.4 3.7 5.7 2.9 7.3 2.1 10.2 3.5 2.1 1.9 5.7 3.0 1.5 3.9 2.5 6.6 1.3 2.7 0.5 5.5 3.8 4.1 2.7 5.7 8.8 3.9 3.5 15.8 3.3 3.3 1.3 12.2 4.4 0.8 6.1 1.8 3.2 1.8 1.9 4.4 5.2 8.2 4.5 5.5 2.6 2.7 4.1 2.5 1.2 5.3 11.7 1.2 3.0 0.0 1.7 2.9 18.8 21.5 2.3 2.3 10.5 2.5 5.8 2.2 1.0 THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 47.1;Microglial cells: 15.0;T-cells: 59.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 22 "gdT-cell: 26.7;MAIT T-cell: 34.0;memory CD4 T-cell: 33.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.0;naive CD8 T-cell: 58.3" "Lineage enriched" "Detected in single" 88 "T-cells: 58.3" "Group enriched" "Detected in some" 4 "HDLM-2: 32.6;JURKAT: 54.1;MOLT-4: 51.6;RPMI-8226: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Cytosol Nucleoplasm "HPA031422: AB_2673874, HPA031425: AB_10670129" "unprognostic (1.47e-4)" "unprognostic (2.50e-3)" "unprognostic (1.31e-2)" "unprognostic (1.41e-4)" "unprognostic (1.41e-1)" "unprognostic (5.20e-3)" "unprognostic (7.48e-3)" "unprognostic (9.01e-3)" "unprognostic (1.47e-1)" "unprognostic (7.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-4)" "unprognostic (2.04e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-2)" 0.4 0.5 0.5 3.3 3.2 1.7 0.6 0.1 2.3 0.4 0.3 0.7 1.6 0.2 0.4 0.6 0.2 1.4 0.1 0.9 0.1 0.2 0.7 1.4 7.5 0.6 0.3 0.1 0.3 0.0 0.0 0.1 0.4 0.4 0.9 0.0 0.9 0.1 0.1 0.2 2.3 0.3 0.3 3.2 1.5 0.1 0.3 32.9 0.4 0.1 4.0 1.1 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 26.7 0.1 34.0 0.1 33.5 48.9 0.2 0.2 30.0 58.3 0.6 0.1 0.2 0.2 1.7 20.3 0.5 3.2 0.1 2.3 0.9 0.1 0.6 0.3 0.4 0.3 0.3 1.9 0.5 0.0 3.0 2.9 2.0 0.5 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.9 0.1 0.2 0.4 0.0 1.7 47.1 0.0 0.0 0.7 5.1 0.1 1.3 0.0 1.1 0.1 0.1 0.0 0.9 0.0 0.0 0.8 0.8 0.2 0.0 1.5 7.2 15.0 1.4 0.0 0.0 0.0 9.7 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.1 1.4 0.0 59.9 0.0 0.0 0.1 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 130.8;Endothelial cells: 108.8;Hepatic stellate cells: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in some" 4 "EFO-21: 106.3;HUVEC TERT2: 238.4;TIME: 210.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 47.0 10.1 16.6 8.1 14.8 0.9 37.8 14.6 16.9 14.0 10.1 11.2 5.2 20.4 5.3 6.5 16.0 13.3 34.2 13.1 14.2 19.8 6.7 35.3 10.1 16.4 16.5 7.5 4.2 3.2 8.0 48.6 16.8 10.8 3.1 0.4 7.4 6.5 14.0 7.9 11.0 14.1 13.9 19.9 8.8 3.0 21.1 2.1 24.2 20.7 2.9 15.1 11.8 14.8 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 106.3 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 41.9 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.7 238.4 0.0 0.0 0.0 0.0 0.0 0.0 20.4 1.3 0.0 0.1 8.1 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.1 210.0 1.2 0.4 0.0 0.2 0.0 0.2 0.4 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 16.6 14.8 14.6 16.9 13.1 14.2 16.4 16.5 16.8 13.9 21.1 14.8 130.8 0.0 4.2 0.0 0.4 2.2 0.6 0.0 1.2 0.3 1.0 0.9 4.9 1.5 1.8 0.0 0.0 0.3 0.7 0.9 0.0 0.0 2.0 0.1 0.4 108.8 0.0 2.5 0.4 0.2 0.1 3.1 0.0 0.4 20.3 0.1 128.8 1.3 0.5 0.0 0.2 0.1 0.0 5.6 3.1 2.5 2.1 1.1 1.8 29.0 0.1 0.1 1.0 1.0 1.1 0.0 0.0 0.7 0.1 0.7 0.1 0.9 3.6 0.9 0.0 2.2 2.2 0.9 0.7 0.5 1.4 0.3 2.3 0.5 0.2 0.7 TIGD5 FLJ14926 ENSG00000179886 "Tigger transposable element derived 5" Q53EQ6 8 143597831-143603224 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.9;Theca cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.90e-1)" "unprognostic (7.91e-2)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.22e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (2.79e-2)" "unprognostic (1.12e-1)" "unprognostic (6.72e-2)" "unprognostic (2.75e-3)" "unprognostic (3.16e-1)" "prognostic favorable (9.16e-5)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (2.32e-1)" "unprognostic (4.04e-1)" 2.1 2.9 1.8 0.2 1.6 0.1 2.1 4.0 2.0 3.0 0.5 3.1 0.4 3.2 0.1 3.5 3.0 0.2 3.6 1.5 1.6 3.0 2.3 1.7 0.3 2.1 2.0 4.0 5.9 0.7 3.8 0.1 1.7 3.0 0.1 0.1 2.7 0.3 4.4 3.7 2.7 0.1 1.5 3.6 3.0 1.5 1.7 0.2 3.0 0.4 0.2 3.2 2.5 2.0 0.9 1.5 0.4 1.2 0.6 0.6 0.6 0.5 0.4 0.5 0.4 0.5 0.6 1.7 2.7 0.4 0.5 1.2 0.4 0.4 0.0 5.9 1.8 1.0 1.7 0.2 1.1 0.4 1.4 0.6 1.1 0.3 0.5 0.7 0.4 0.4 1.2 0.2 0.2 1.6 2.9 1.7 0.6 1.0 2.9 1.1 0.3 0.8 0.5 0.6 1.4 1.8 1.1 0.9 1.2 0.1 2.6 1.2 0.7 1.0 0.8 1.0 3.5 0.9 0.4 0.2 0.6 0.7 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 1.6 4.0 2.0 1.5 1.6 2.1 2.0 1.7 1.5 1.7 2.0 5.0 3.2 1.3 0.7 3.8 1.7 5.4 0.9 1.2 16.0 6.3 4.6 5.9 4.3 1.3 5.5 20.9 1.4 4.9 5.1 0.0 2.3 1.0 4.0 8.1 4.4 0.0 4.0 0.8 1.8 1.3 4.2 2.0 5.5 1.3 15.4 4.6 2.6 3.4 16.8 1.1 3.6 0.0 3.2 0.8 0.7 7.8 3.0 0.0 1.0 3.2 10.0 6.2 0.5 0.4 3.6 1.7 4.5 1.0 4.9 3.3 2.2 1.1 15.1 0.0 10.6 4.2 0.8 1.2 2.4 1.0 1.8 3.5 29.3 5.1 3.8 TIGIT "DKFZp667A205, FLJ39873, VSIG9, VSTM3" ENSG00000181847 "T cell immunoreceptor with Ig and ITIM domains" Q495A1 3 114276913-114310288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 38.7" "Group enriched" "Detected in some" 10 "dendritic cells: 64.2;NK-cells: 69.0;T-cells: 78.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 195.5" "Lineage enriched" "Detected in many" 11 "T-cells: 195.5" "Cell line enhanced" "Detected in single" "HDLM-2: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.24e-2)" "prognostic favorable (5.43e-4)" "unprognostic (1.22e-3)" "unprognostic (2.22e-6)" "unprognostic (9.84e-2)" "prognostic favorable (3.96e-4)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (5.50e-4)" "unprognostic (3.51e-3)" "unprognostic (1.78e-1)" "unprognostic (3.15e-1)" "unprognostic (2.30e-8)" "unprognostic (3.54e-2)" "unprognostic (1.33e-1)" "unprognostic (7.62e-2)" "unprognostic (6.18e-3)" 0.7 0.3 0.3 12.1 0.5 2.1 0.7 0.6 0.5 0.8 0.2 2.1 1.7 0.9 0.7 2.1 0.5 3.6 0.7 0.4 0.4 0.4 2.9 2.9 38.7 0.8 0.5 0.5 0.2 0.1 0.2 0.3 0.7 1.4 2.4 0.3 1.8 0.2 0.1 1.0 5.2 0.9 0.4 15.0 3.7 0.8 0.7 9.0 0.9 0.0 20.4 5.1 0.5 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.5 0.0 0.2 0.1 0.0 0.4 0.2 0.1 29.8 0.2 3.5 1.4 48.5 90.3 0.2 0.9 5.2 39.8 0.7 17.3 0.2 1.0 195.5 22.0 0.3 0.5 0.6 0.5 0.4 0.4 0.8 0.5 0.7 0.4 0.7 0.9 0.9 0.0 3.3 0.0 3.7 3.1 0.1 0.0 0.6 0.4 0.4 0.6 0.6 0.0 1.3 0.0 2.1 0.1 64.2 0.0 0.0 0.0 0.0 0.2 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.9 2.6 0.4 1.3 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 1.8 4.2 0.3 0.0 2.3 3.6 0.0 0.9 0.1 69.0 0.0 0.1 0.0 0.0 0.0 6.9 0.2 0.0 0.1 0.0 0.6 0.0 1.0 0.5 0.7 3.0 0.2 3.3 0.0 78.4 0.0 0.2 0.0 TIMELESS "hTIM, TIM, TIM1" ENSG00000111602 "Timeless circadian regulator" Q9UNS1 12 56416363-56449426 "Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.5;Spermatogonia: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA060655 Enhanced Supported Nucleoplasm No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA060655: AB_2684338" "unprognostic (3.94e-2)" "unprognostic (1.10e-2)" "unprognostic (1.29e-2)" "unprognostic (2.18e-2)" "unprognostic (2.36e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (1.43e-3)" "prognostic unfavorable (1.06e-5)" "unprognostic (7.03e-2)" "unprognostic (2.53e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (9.47e-3)" "unprognostic (1.72e-1)" "unprognostic (1.92e-2)" "unprognostic (5.01e-2)" 3.4 3.4 1.6 11.0 2.1 22.0 4.5 2.1 2.1 4.1 2.7 6.7 6.0 4.4 2.5 6.8 3.1 3.3 1.8 1.5 2.1 3.8 9.8 4.1 15.3 2.4 2.4 1.9 5.0 5.9 5.4 8.7 2.5 3.2 8.5 13.7 3.9 3.4 3.4 5.5 6.2 5.6 2.1 6.8 5.5 6.2 2.6 19.8 4.7 1.6 17.9 4.7 3.9 2.5 39.4 89.1 111.4 51.9 9.9 9.9 62.8 41.9 25.3 58.3 46.0 45.6 56.5 113.3 41.5 24.5 29.4 32.8 82.0 32.7 53.5 54.2 45.7 86.9 47.6 33.6 5.1 66.2 62.2 6.9 10.3 41.9 25.2 16.0 31.5 67.3 82.7 99.5 49.8 77.2 94.7 51.2 79.2 49.5 36.8 93.5 56.7 55.5 22.7 49.5 85.4 58.9 78.2 43.9 12.2 45.6 77.4 51.8 18.9 45.3 45.1 41.8 35.0 37.3 50.9 62.8 21.1 39.9 55.5 0.1 0.6 0.4 1.8 1.5 0.3 3.3 1.1 1.2 1.0 4.9 0.8 0.3 0.2 1.5 1.1 1.2 1.5 1.1 1.6 2.1 2.1 2.1 1.5 2.1 2.4 2.4 2.5 2.1 2.6 2.5 2.6 0.0 5.0 2.3 8.2 3.3 3.0 3.0 6.8 57.5 3.1 3.4 2.1 2.8 6.8 7.3 2.1 15.9 1.8 2.7 0.0 4.8 6.9 2.5 3.9 5.0 1.8 16.6 0.9 5.7 20.9 3.7 6.6 4.8 5.7 15.5 4.6 10.6 8.5 6.7 1.3 5.2 4.1 2.6 3.7 2.9 1.2 4.6 0.0 1.9 4.2 4.8 4.1 0.5 3.2 3.7 0.6 1.2 18.2 4.2 1.1 2.0 3.4 17.8 0.0 2.7 7.0 1.6 24.5 12.1 1.4 9.2 6.1 3.2 8.5 3.0 TIMM29 "C19orf52, TIM29" ENSG00000142444 "Translocase of inner mitochondrial membrane 29" Q9BSF4 19 10928811-10933535 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.0;Ductal cells: 21.6;Extravillous trophoblasts: 31.4;Hofbauer cells: 22.4;Proximal tubular cells: 22.1;Syncytiotrophoblasts: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041858 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "HPA041858: AB_10963429" "unprognostic (8.45e-2)" "prognostic favorable (9.93e-5)" "unprognostic (8.99e-2)" "unprognostic (5.21e-2)" "unprognostic (9.31e-2)" "unprognostic (8.10e-2)" "unprognostic (2.82e-3)" "unprognostic (1.42e-2)" "unprognostic (1.81e-1)" "unprognostic (5.92e-2)" "unprognostic (5.26e-3)" "unprognostic (1.80e-1)" "unprognostic (3.79e-3)" "prognostic favorable (7.03e-7)" "unprognostic (1.10e-1)" "unprognostic (2.35e-1)" "unprognostic (7.26e-3)" 8.4 11.7 4.6 5.4 4.5 10.1 8.4 3.7 6.1 10.4 3.5 11.0 8.0 11.0 1.1 14.9 9.0 3.1 13.5 4.9 3.8 11.5 12.2 8.1 6.0 5.8 4.3 7.9 9.9 3.3 10.7 4.6 4.2 10.1 2.0 1.1 10.1 3.8 23.5 13.9 9.7 2.1 3.8 10.7 11.0 13.0 4.2 5.3 7.5 5.9 2.8 10.5 11.4 4.7 21.3 8.0 6.2 10.4 5.3 5.1 16.7 14.3 7.6 10.7 9.9 14.7 7.0 18.0 24.7 7.0 5.8 20.1 3.3 8.9 1.8 21.3 25.0 20.7 8.4 10.0 8.4 15.8 15.5 4.5 8.6 7.5 3.2 4.3 6.5 15.7 23.1 15.4 4.1 19.0 17.4 29.1 21.8 6.6 34.0 23.4 8.7 22.3 4.7 8.6 15.6 15.8 16.9 9.1 18.3 2.3 13.1 16.7 10.7 17.1 10.0 21.6 23.1 49.7 52.8 19.8 10.6 19.3 14.8 3.7 8.7 9.8 5.3 9.3 8.9 17.9 10.6 11.7 5.8 15.0 10.1 8.3 1.7 11.3 7.4 11.0 12.8 3.8 4.6 4.5 3.7 6.1 4.9 3.8 5.8 4.3 4.2 3.8 4.2 4.7 6.9 3.2 5.8 0.0 3.5 0.0 0.0 0.0 0.0 0.0 9.6 8.4 0.0 0.0 1.3 16.5 0.0 36.0 13.8 0.0 19.6 21.6 0.0 9.6 10.9 4.9 0.0 0.0 0.0 10.5 31.4 5.2 0.0 9.2 1.3 10.5 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 2.4 0.0 0.0 22.1 0.7 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 35.7 5.5 14.7 0.0 0.0 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1235.1;Sertoli cells: 427.3;Syncytiotrophoblasts: 1946.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 322.7;CAPAN-2: 178.9;EFO-21: 403.6;HaCaT: 181.4;HBEC3-KT: 211.9;HUVEC TERT2: 173.4;TIME: 376.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" NA NA 370000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" 173.7 40.8 19.0 18.5 17.7 0.9 150.5 17.9 19.9 86.8 16.4 83.2 26.7 101.8 10.7 31.0 82.4 23.9 230.7 15.2 17.9 177.7 22.7 85.7 8.5 19.6 18.3 38.8 31.0 13.2 25.3 183.6 19.8 71.2 16.5 1.0 63.8 40.6 46.6 37.0 51.6 36.5 16.4 119.6 66.4 6.2 21.2 3.8 115.1 30.6 5.3 88.4 70.2 17.1 96.6 0.2 0.0 0.5 0.8 0.2 322.7 14.9 1.9 0.7 0.4 44.5 178.9 0.2 403.6 13.4 7.0 181.4 0.2 211.9 0.1 0.7 0.1 0.1 7.3 11.5 4.5 0.1 0.5 0.2 37.9 0.0 7.6 0.1 173.4 0.1 2.4 0.4 0.0 0.0 0.7 0.6 0.9 52.6 6.1 0.4 0.1 0.4 57.0 72.6 0.4 0.5 38.0 125.6 4.2 18.8 7.5 0.3 376.6 0.3 91.6 0.7 2.8 0.4 0.5 1.6 0.2 0.2 3.3 2.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.8 0.4 0.1 0.1 0.1 0.0 19.0 17.7 17.9 19.9 15.2 17.9 19.6 18.3 19.8 16.4 21.2 17.1 345.4 9.6 5.8 0.7 2.7 11.0 121.5 244.1 8.0 0.0 32.0 73.0 46.7 37.1 28.6 132.4 0.0 1235.1 2.6 158.9 1.9 378.7 1.4 8.4 3.2 161.4 11.4 13.5 0.1 92.2 223.5 35.0 50.0 14.4 14.7 49.7 306.6 4.4 89.3 0.0 1.1 35.5 14.2 8.8 10.3 0.7 7.5 4.2 23.2 13.1 2.0 0.2 0.0 0.5 0.0 344.6 115.3 4.1 0.2 131.4 45.2 80.9 9.1 0.4 427.3 9.5 357.4 0.3 0.8 4.9 6.5 1946.1 3.8 2.7 59.7 219.4 TINCR "FLJ90734, LINC00036, NCRNA00036, onco-lncRNA-16, PLAC2" ENSG00000223573 "TINCR ubiquitin domain containing" 19 5558167-5578349 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "skin 1: 119.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.4;Cytotrophoblasts: 61.0;Extravillous trophoblasts: 116.9;Squamous epithelial cells: 53.3;Suprabasal keratinocytes: 92.2;Syncytiotrophoblasts: 204.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 53.3;HaCaT: 35.9;MCF7: 14.9;SK-BR-3: 56.1" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (4.75e-2)" "unprognostic (2.99e-2)" "unprognostic (7.78e-2)" "unprognostic (1.78e-3)" "unprognostic (3.69e-1)" "unprognostic (2.54e-3)" "unprognostic (3.38e-2)" "unprognostic (3.95e-1)" "unprognostic (3.07e-1)" "unprognostic (1.66e-2)" "unprognostic (8.87e-2)" "unprognostic (1.24e-1)" "unprognostic (0.00e+0)" "unprognostic (4.22e-2)" "unprognostic (1.16e-1)" "unprognostic (3.63e-2)" "unprognostic (7.32e-2)" 0.9 1.9 6.6 0.7 6.6 2.9 3.6 4.7 8.0 5.7 1.0 2.0 0.5 0.6 1.5 21.2 0.7 0.5 0.5 4.9 4.8 1.1 0.1 2.9 0.9 4.1 7.3 0.6 0.3 0.3 2.9 17.8 7.2 4.7 2.5 2.8 4.3 0.8 0.9 119.1 0.8 0.4 0.6 0.9 0.3 1.7 11.7 0.2 0.5 0.0 4.9 1.4 13.7 4.4 2.0 1.6 0.2 0.6 0.5 1.0 53.3 0.2 0.1 0.1 0.2 0.9 6.3 0.3 0.5 0.2 0.5 35.9 0.6 0.1 0.4 0.6 1.2 0.4 1.9 0.5 0.1 0.7 0.5 0.0 11.5 0.3 0.3 0.3 0.0 2.9 0.3 0.8 0.1 14.9 0.2 0.8 1.0 1.4 2.5 1.2 0.4 1.3 0.0 3.8 0.7 0.1 3.9 56.1 5.6 5.0 6.7 0.5 0.0 0.6 0.5 1.0 0.1 1.4 0.4 1.0 0.3 0.7 1.1 3.2 0.4 0.5 0.4 0.3 0.3 0.9 0.3 0.3 0.1 0.9 0.3 0.4 2.3 0.6 0.4 1.3 0.4 0.2 6.6 6.6 4.7 8.0 4.9 4.8 4.1 7.3 7.2 0.6 11.7 4.4 2.1 12.8 1.7 0.3 0.6 46.4 5.2 2.9 21.1 4.2 6.1 3.2 1.3 4.3 2.6 1.8 0.0 61.0 1.4 3.3 11.7 0.0 0.4 1.2 1.8 2.4 1.8 0.0 0.8 0.5 116.9 1.7 0.0 2.6 0.0 0.5 2.9 0.3 6.6 0.0 1.2 3.0 4.1 1.4 4.6 0.2 0.6 1.2 7.2 0.0 0.5 3.5 1.0 0.0 0.2 0.1 7.5 0.7 0.1 5.9 0.1 0.4 1.9 2.1 0.0 3.6 1.3 1.0 3.1 53.3 92.2 204.5 1.1 0.2 0.9 10.1 TK1 ENSG00000167900 "Thymidine kinase 1" P04183 17 78174091-78187233 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 92.8;Erythroid cells: 108.6;Extravillous trophoblasts: 210.4;Hofbauer cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 34.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enhanced" "Detected in some" "white matter: 3.6" "Low region specificity" "Detected in many" CAB004683 Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB004683: AB_437067" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.14e-3)" "unprognostic (3.22e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (6.87e-4)" "prognostic unfavorable (3.03e-5)" "unprognostic (4.05e-2)" "unprognostic (3.18e-3)" "unprognostic (6.64e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (6.50e-11)" "unprognostic (5.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (4.94e-2)" 3.7 2.7 2.5 20.4 3.4 77.9 5.9 3.6 3.4 5.9 1.3 24.4 18.0 3.0 0.2 27.2 4.9 3.4 2.8 2.7 2.4 11.0 9.2 9.1 34.8 3.4 3.3 1.3 5.6 0.6 0.6 14.8 3.3 3.4 15.7 0.1 6.3 1.5 5.5 14.2 18.3 10.1 2.6 12.4 17.9 3.1 3.8 25.1 2.0 1.6 30.6 5.5 9.0 4.4 443.9 357.7 68.2 92.5 7.6 28.0 47.3 207.6 113.2 323.1 442.3 324.2 178.7 144.1 72.9 131.7 133.9 204.2 63.4 187.1 158.0 51.2 230.4 252.5 119.9 213.3 2.2 107.1 162.9 13.8 7.1 166.1 22.5 22.3 137.9 49.4 156.7 311.9 130.8 352.0 56.0 68.6 36.7 259.1 240.9 152.6 276.4 324.1 90.6 138.5 33.6 94.2 162.0 481.2 59.7 59.4 303.9 156.1 57.8 302.3 305.7 219.9 292.1 132.5 71.4 181.9 149.0 71.9 142.1 0.0 1.1 0.0 1.8 2.1 0.7 5.8 7.9 4.0 3.4 1.7 0.4 2.2 1.8 10.8 1.7 1.1 34.0 5.5 2.5 3.4 3.6 3.4 2.7 2.4 3.4 3.3 3.3 2.6 3.8 4.4 1.6 0.0 2.7 0.0 17.1 28.4 13.3 17.8 2.2 0.0 10.6 9.4 0.9 2.8 8.3 12.9 0.0 92.8 3.6 35.0 7.9 7.7 3.0 9.2 3.3 10.6 5.4 108.6 0.3 11.2 210.4 15.7 19.4 7.0 0.0 15.9 7.5 10.5 65.2 0.0 0.2 32.7 8.2 15.5 19.1 6.8 0.6 10.9 3.6 0.0 5.7 0.0 3.1 0.0 1.0 9.6 7.5 0.7 53.6 4.9 3.1 17.5 5.8 0.0 0.0 1.7 20.1 3.8 16.8 24.7 11.2 51.0 8.7 1.7 60.8 24.0 TLCD2 ENSG00000185561 "TLC domain containing 2" A6NGC4 17 1702816-1710377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 112.4;Proximal enterocytes: 68.9;Skeletal myocytes: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 3.4;neutrophil: 1.6" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.0;HaCaT: 8.4;SiHa: 11.2;T-47d: 9.4" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 14.2" HPA046063 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA046063: AB_2679520" "unprognostic (1.78e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (4.04e-2)" "unprognostic (7.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.36e-5)" "unprognostic (3.77e-2)" "unprognostic (2.82e-1)" "unprognostic (7.79e-2)" "unprognostic (4.44e-2)" 10.3 9.4 0.6 1.8 0.7 2.1 4.7 1.6 0.9 3.0 2.3 7.3 6.0 1.8 1.2 4.7 2.7 1.8 2.1 0.6 0.5 1.8 7.0 3.9 0.7 1.0 0.7 2.5 1.2 1.0 1.1 1.5 1.0 1.9 5.3 10.5 2.9 0.9 1.7 2.4 6.9 1.2 0.7 1.3 4.7 0.6 1.0 0.1 1.6 0.8 0.8 3.1 3.5 1.6 1.0 1.1 1.1 3.5 8.1 9.0 0.3 1.9 1.8 1.0 0.7 6.9 3.1 0.1 1.9 3.1 1.0 8.4 1.5 0.9 0.7 0.2 0.7 0.9 2.4 0.3 2.3 0.1 2.4 7.6 3.2 1.2 2.2 2.9 0.7 0.1 0.8 0.4 0.9 1.9 0.1 0.4 0.1 3.4 0.6 0.1 5.3 0.2 0.7 2.7 0.2 0.4 11.2 1.0 1.6 1.5 9.4 0.8 2.6 0.5 2.3 2.1 0.5 0.1 0.1 0.1 0.6 0.3 1.0 3.4 0.2 0.4 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.4 0.2 0.2 1.6 0.3 0.1 0.2 0.1 0.1 0.6 0.7 1.6 0.9 0.6 0.5 1.0 0.7 1.0 0.7 1.0 1.6 19.0 51.3 55.5 0.3 1.6 0.0 8.2 0.0 4.0 7.9 5.8 9.5 2.7 17.2 18.0 11.0 129.3 4.9 2.0 112.4 0.0 7.3 1.1 12.9 10.4 14.1 9.0 11.2 0.5 9.6 2.6 14.9 20.9 13.3 15.8 3.9 18.9 24.2 5.5 0.0 0.4 24.6 0.0 6.5 0.0 1.8 13.4 10.7 0.0 3.7 1.4 11.7 0.0 0.0 0.1 13.5 40.1 5.7 3.3 6.3 68.9 1.1 19.9 57.8 6.6 124.2 17.8 0.6 0.8 9.1 0.3 4.0 5.1 5.4 35.7 13.0 TLR8 CD288 ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.7;lymphoid tissue: 16.8" "Group enriched" "Detected in some" 6 "Kupffer cells: 49.8;Macrophages: 21.1;monocytes: 39.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 74 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 78 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001608 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" 3.6 0.5 0.2 16.8 0.2 5.7 0.9 0.2 0.3 0.7 0.5 1.7 0.8 0.4 0.1 0.9 0.6 2.5 0.8 0.1 0.3 0.5 2.2 10.7 6.1 1.1 0.7 0.4 0.6 0.3 0.1 4.3 0.8 0.3 1.8 0.0 0.3 0.2 0.2 0.2 1.5 3.8 0.5 13.3 0.8 0.4 0.4 1.7 0.4 1.3 1.9 3.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 14.9 0.0 0.2 0.0 0.0 8.4 0.0 0.0 0.0 27.6 0.0 15.6 0.0 0.0 3.8 0.2 0.2 0.2 0.3 0.1 0.3 1.1 0.7 0.8 0.5 0.4 0.9 0.0 0.0 3.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.7 5.3 0.0 0.0 0.0 0.0 49.8 5.1 0.0 0.0 21.1 0.0 0.0 39.7 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TM4SF1 "L6, M3S1" ENSG00000169908 "Transmembrane 4 L six family member 1" P30408 3 149369022-149377692 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 5463.1;Endothelial cells: 1843.0;Pancreatic endocrine cells: 2557.3;Prostatic glandular cells: 2717.0;Urothelial cells: 4902.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 703.8;hTERT-RPE1: 925.5;HUVEC TERT2: 633.3;LHCN-M2: 687.7;OE19: 672.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002760, HPA002823" Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB002760: , HPA002823: AB_1079221" "unprognostic (1.94e-1)" "unprognostic (2.25e-2)" "unprognostic (5.20e-2)" "unprognostic (4.79e-2)" "unprognostic (2.89e-2)" "unprognostic (2.47e-3)" "unprognostic (3.85e-3)" "unprognostic (2.74e-2)" "unprognostic (5.09e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.06e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (4.67e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.43e-6)" 365.9 71.3 41.9 50.5 43.1 2.6 192.8 44.1 68.2 82.6 65.6 61.6 38.3 74.9 58.2 210.9 74.7 237.6 181.7 42.2 45.2 155.1 92.6 229.8 25.2 45.1 43.9 49.7 211.7 19.9 20.2 194.6 47.7 79.9 59.9 6.0 180.9 32.0 50.2 63.5 62.2 94.6 45.4 120.5 129.7 19.5 53.5 17.0 72.5 64.2 60.2 150.9 115.5 45.9 367.9 401.9 0.0 1.0 108.4 422.2 0.6 115.2 455.5 23.9 8.8 159.7 703.8 0.1 351.3 23.5 545.5 434.0 1.9 80.0 22.9 0.9 0.0 3.9 391.8 521.8 39.4 0.0 0.5 40.0 19.1 169.7 81.5 925.5 633.3 0.0 0.3 0.8 687.7 0.5 0.0 0.7 1.5 672.9 170.7 0.2 0.9 0.8 449.3 54.8 0.2 0.5 46.8 25.1 4.4 6.0 0.8 1.7 404.7 233.6 38.9 4.8 244.3 0.5 0.7 1.1 337.4 0.4 62.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.9 43.1 44.1 68.2 42.2 45.2 45.1 43.9 47.7 45.4 53.5 45.9 1131.0 576.9 342.3 0.3 7.5 278.0 5463.1 668.3 272.6 0.1 956.5 363.1 24.0 274.5 984.3 57.0 0.0 0.8 17.0 176.6 0.0 1383.5 5.2 514.1 168.0 1843.0 39.2 15.6 0.0 1600.9 0.9 297.2 147.8 1807.5 31.5 0.2 1263.6 21.8 1.9 0.0 0.0 15.9 382.5 27.8 222.1 11.3 255.7 35.6 300.6 30.9 26.4 0.0 0.0 0.0 0.3 2557.3 251.8 176.0 11.1 2717.0 0.3 1.2 238.5 0.0 322.1 37.7 311.0 6.6 1.4 925.8 253.7 1.4 44.1 44.2 46.6 4902.9 TMC4 ENSG00000167608 "Transmembrane channel like 4" 19 54160108-54173250 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 45.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 160.1;Paneth cells: 119.7;Proximal enterocytes: 228.6;Respiratory ciliated cells: 155.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "OE19: 17.3;T-47d: 30.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA048635 Approved Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA048635: AB_2680470" "unprognostic (7.55e-2)" "unprognostic (1.66e-1)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.82e-2)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-3)" "unprognostic (7.59e-2)" "unprognostic (3.09e-1)" "prognostic favorable (1.54e-8)" "unprognostic (6.70e-2)" "unprognostic (2.48e-1)" "unprognostic (8.94e-2)" "unprognostic (1.79e-2)" 2.3 0.4 0.2 0.4 0.2 0.0 12.5 0.3 0.7 8.7 0.0 38.6 33.1 3.2 0.0 14.8 16.8 8.4 5.7 0.3 0.2 25.5 2.6 11.9 0.1 0.5 0.8 1.1 45.6 4.5 21.0 0.7 0.7 21.6 12.0 0.0 42.1 4.9 1.4 5.4 37.2 0.4 0.2 0.2 31.9 0.5 0.2 0.0 31.3 0.1 0.5 18.9 9.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 17.3 0.0 0.1 0.0 0.7 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.7 0.3 0.2 0.5 0.8 0.7 0.2 0.2 0.1 1.5 28.9 30.0 0.7 1.5 2.4 26.9 78.6 24.5 0.3 42.5 19.8 1.7 51.5 94.4 46.0 0.0 22.7 3.7 160.1 13.7 78.2 0.0 59.7 6.6 2.2 41.6 0.0 0.6 64.1 6.1 1.8 102.4 56.2 5.7 0.5 1.1 0.6 3.9 0.0 0.6 92.7 57.0 1.3 3.0 0.1 1.2 3.2 1.8 0.0 2.1 0.1 4.1 1.0 0.7 50.7 119.7 0.7 2.4 22.0 228.6 29.0 155.7 0.5 26.3 0.9 13.6 0.4 1.9 22.0 1.7 23.4 2.8 2.1 77.1 43.1 TMC6 "EVER1, EVIN1, LAK-4P, TNRC6C-AS1" ENSG00000141524 "Transmembrane channel like 6" Q7Z403 17 78107397-78132407 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 110.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 108.7;SK-BR-3: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051430 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA051430: AB_2681483" "unprognostic (6.34e-2)" "unprognostic (5.14e-2)" "unprognostic (5.55e-2)" "unprognostic (2.81e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" "unprognostic (5.36e-2)" "unprognostic (6.27e-2)" "unprognostic (1.47e-1)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (6.61e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.82e-4)" "unprognostic (2.70e-2)" "unprognostic (1.10e-2)" "prognostic favorable (3.20e-4)" 29.5 6.8 19.2 45.4 50.5 72.7 25.2 43.4 33.5 11.3 5.2 23.5 21.7 7.6 1.0 25.4 14.1 9.7 35.9 19.3 26.4 20.6 9.1 40.3 69.7 59.3 49.7 3.8 14.6 3.1 5.6 8.8 55.9 20.2 6.6 0.6 29.3 7.9 3.5 17.9 50.6 3.5 35.8 110.5 14.6 2.6 48.4 26.3 12.9 1.8 32.4 14.6 18.4 81.9 17.9 14.0 7.5 6.0 0.0 0.0 15.2 0.0 0.0 0.2 0.2 25.2 19.2 19.7 23.7 0.0 6.3 31.0 1.0 5.9 0.0 2.0 11.3 41.3 4.2 31.0 1.9 38.3 67.0 1.1 16.2 0.0 1.3 0.2 14.7 9.2 108.7 73.3 0.0 36.1 18.9 65.4 5.9 32.9 4.9 8.4 0.6 58.9 11.4 65.1 1.9 4.9 5.7 121.0 33.2 9.7 68.7 57.6 5.2 0.0 8.7 0.1 0.3 57.6 27.3 13.2 0.0 60.4 1.0 17.7 11.6 23.2 56.2 38.3 49.0 28.5 41.7 46.2 18.6 21.7 36.5 39.6 15.3 35.8 63.5 5.7 38.0 33.5 19.2 50.5 43.4 33.5 19.3 26.4 59.3 49.7 55.9 35.8 48.4 81.9 43.8 41.7 29.6 8.1 69.5 11.1 21.0 22.3 7.4 3.2 17.4 6.5 14.7 10.0 41.5 16.5 0.0 1.2 79.8 25.0 0.0 41.2 0.3 5.1 1.6 19.7 9.1 28.4 0.2 23.1 26.4 4.6 10.2 8.0 40.5 0.7 23.6 2.2 67.0 1.7 0.2 14.0 40.7 66.2 29.9 1.2 9.6 44.7 14.2 20.6 62.0 7.5 85.5 1.5 50.8 40.5 53.7 1.2 62.6 31.5 20.3 2.0 20.3 1.8 13.1 4.6 13.5 0.5 2.2 8.4 10.2 3.7 83.7 2.5 30.3 37.4 TMC7 FLJ21240 ENSG00000170537 "Transmembrane channel like 7" Q7Z402 16 18983934-19063942 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;testis: 9.6" "Group enriched" "Detected in many" 6 "Early spermatids: 172.0;Late spermatids: 44.6;Oligodendrocytes: 96.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029465 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA029465: AB_10600914" "unprognostic (1.80e-4)" "unprognostic (6.13e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.25e-1)" "unprognostic (1.19e-3)" "unprognostic (7.60e-5)" "prognostic unfavorable (3.20e-4)" "unprognostic (7.60e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.64e-4)" "unprognostic (3.39e-1)" "unprognostic (1.00e-1)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (5.66e-2)" "prognostic favorable (9.20e-4)" 2.1 0.2 6.0 1.0 15.8 0.3 1.7 12.4 10.6 0.5 0.4 3.8 2.5 0.7 0.6 0.4 0.4 1.4 1.4 7.0 9.0 0.6 0.3 2.9 0.3 13.8 13.2 0.2 0.4 0.4 0.3 4.3 12.6 1.5 4.5 1.1 0.4 0.9 0.9 1.1 2.7 1.1 7.5 0.6 3.1 9.6 15.0 0.2 0.8 0.9 0.2 8.1 0.8 23.9 1.9 3.5 1.0 1.9 0.2 1.6 4.8 0.6 1.0 0.7 1.5 1.2 8.5 0.2 7.9 0.7 1.8 6.8 2.9 2.8 0.9 0.1 2.0 0.1 3.6 5.5 0.2 0.2 0.1 0.3 4.1 6.5 7.2 2.2 2.6 3.8 2.2 0.2 2.8 3.9 0.3 0.3 3.1 11.1 5.1 0.2 3.1 0.2 1.3 8.7 0.6 1.9 2.1 5.4 0.6 4.9 1.7 0.6 2.3 1.1 1.8 1.3 3.3 0.4 0.9 0.2 5.4 0.3 1.0 0.7 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.0 6.0 15.8 12.4 10.6 7.0 9.0 13.8 13.2 12.6 7.5 15.0 23.9 12.6 3.2 6.2 3.9 0.1 0.4 4.4 3.2 0.0 0.6 1.3 0.4 0.7 1.5 2.0 0.0 0.0 0.2 0.0 13.4 0.0 4.1 172.0 1.4 0.4 4.9 1.2 2.7 7.5 11.0 2.3 0.6 9.2 2.4 0.0 1.2 4.6 0.2 0.2 0.0 12.1 6.0 4.1 0.0 1.2 44.6 1.2 0.6 0.0 6.5 0.2 0.3 2.1 6.6 96.5 14.0 8.0 0.4 0.1 2.3 3.6 0.3 0.9 2.7 0.0 1.6 2.2 6.9 12.1 1.9 1.0 0.3 0.4 0.1 7.6 17.3 TMEM100 "FLJ10970, FLJ37856" ENSG00000166292 "Transmembrane protein 100" Q9NV29 17 55719627-55732121 "Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 192.5" "Cell type enhanced" "Detected in some" "Adipocytes: 57.8;Endothelial cells: 25.5;Fibroblasts: 40.7;Leydig cells: 40.7;Peritubular cells: 52.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 28.9;ASC TERT1: 19.5;HHSteC: 44.8;HSkMC: 20.6;U-87 MG: 13.9;WM-115: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055936 Approved Uncertain Nucleoplasm NA NA "Cluster 19: Lung - Lung function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055936: AB_2682975" "unprognostic (1.35e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (4.02e-2)" "unprognostic (6.78e-3)" "unprognostic (3.07e-1)" "prognostic favorable (2.67e-5)" "unprognostic (5.74e-2)" "unprognostic (1.87e-2)" "unprognostic (4.66e-1)" "unprognostic (1.89e-2)" "unprognostic (8.11e-3)" "prognostic unfavorable (1.32e-4)" "unprognostic (4.91e-3)" "unprognostic (1.12e-1)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" 40.8 5.0 5.4 3.2 5.5 0.0 27.6 4.3 9.0 15.8 6.0 14.5 6.7 3.6 36.6 6.5 8.0 7.3 18.7 5.1 7.0 1.9 7.0 192.5 1.2 5.5 7.0 26.5 2.3 0.8 11.2 54.1 6.0 10.3 11.6 0.4 8.0 24.7 9.7 4.6 13.2 5.5 4.6 6.9 30.2 2.7 8.1 1.1 7.5 14.1 0.6 11.1 8.2 4.7 0.0 0.0 5.9 0.0 28.9 19.5 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 44.8 0.0 0.0 20.6 0.0 1.4 0.1 0.2 0.0 0.3 1.0 0.1 0.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 8.7 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.3 1.9 3.9 0.0 0.8 0.0 0.1 13.9 0.1 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.5 4.3 9.0 5.1 7.0 5.5 7.0 6.0 4.6 8.1 4.7 57.8 0.0 3.6 2.3 0.1 2.5 0.3 0.0 1.2 0.7 0.4 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.1 4.0 25.5 0.0 0.0 0.1 0.0 0.0 40.7 1.5 0.2 1.3 0.1 7.1 15.2 0.1 0.0 1.6 0.0 0.0 0.0 4.9 0.5 40.7 0.2 7.2 1.9 0.0 0.0 0.0 17.1 0.0 0.1 0.0 52.6 0.0 0.1 0.0 3.4 0.0 0.1 32.9 10.3 15.1 0.1 0.2 0.7 2.6 0.1 0.5 0.3 0.0 0.3 TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 8.3;Fibroblasts: 30.5;Late spermatids: 9.3;Melanocytes: 8.8;Microglial cells: 15.0;Peritubular cells: 24.0;Smooth muscle cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 559.2;ASC TERT1: 152.6;BJ hTERT+: 168.0;fHDF/TERT166: 81.9;HSkMC: 238.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" 29.6 8.0 7.6 16.2 8.9 3.0 27.1 8.5 9.2 61.0 5.3 12.6 15.1 18.9 14.1 6.9 11.9 35.8 9.4 7.7 9.3 6.0 0.9 37.6 47.8 17.2 12.1 1.4 7.5 5.6 6.1 6.6 14.9 12.7 15.1 0.9 6.8 26.0 1.6 13.9 23.1 11.2 13.4 11.4 10.5 5.9 16.4 5.1 21.7 1.7 27.2 32.2 18.4 21.9 0.1 0.3 1.3 0.7 559.2 152.6 0.8 11.8 168.0 0.4 3.0 0.2 0.6 0.3 0.4 81.9 0.3 0.2 0.1 0.2 0.1 0.5 0.0 0.3 0.6 1.0 7.2 0.3 1.2 238.4 0.3 7.0 0.1 0.7 0.1 0.2 0.5 0.5 0.5 0.7 0.3 1.6 0.1 0.0 0.9 0.6 0.9 0.8 0.1 0.7 0.2 39.5 0.0 0.3 0.3 4.5 0.2 1.8 1.2 13.1 0.4 11.2 0.5 2.6 3.1 0.6 6.8 0.5 0.1 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.4 0.2 0.1 0.4 0.3 0.3 1.4 0.2 0.4 0.2 0.1 0.1 7.6 8.9 8.5 9.2 7.7 9.3 17.2 12.1 14.9 13.4 16.4 21.9 1.3 0.0 0.0 0.0 0.2 3.8 0.1 0.0 0.6 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 8.3 0.2 5.8 1.3 0.0 0.0 0.0 0.0 0.2 30.5 0.0 0.2 0.0 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 1.9 4.4 9.3 4.1 1.1 8.8 15.0 1.6 0.0 0.0 0.0 0.0 0.1 1.1 24.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 9.7 0.1 0.1 0.0 3.7 0.3 0.7 0.5 0.0 0.1 TMEM134 FLJ21749 ENSG00000172663 "Transmembrane protein 134" Q9H6X4 11 67461710-67469272 "Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043744 Approved Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA043744: AB_10794773" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (4.67e-2)" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (7.22e-2)" "unprognostic (3.85e-1)" "unprognostic (1.39e-2)" "unprognostic (4.30e-2)" "unprognostic (3.48e-1)" "unprognostic (1.75e-1)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-2)" "unprognostic (4.43e-3)" 12.6 24.3 22.5 8.6 23.2 4.7 14.8 21.2 29.9 15.6 19.9 14.0 8.3 9.6 11.0 55.5 10.2 6.5 46.8 21.6 22.2 25.2 33.9 11.2 11.9 22.8 22.6 8.6 42.9 7.9 8.7 5.3 22.4 25.7 4.5 2.8 20.6 7.3 57.4 57.5 14.5 4.4 22.7 16.2 22.4 26.5 22.9 6.6 13.5 26.0 8.8 15.9 25.4 22.5 12.3 4.6 6.5 14.0 4.3 7.3 7.2 2.5 4.6 2.9 1.2 5.8 14.3 11.7 27.2 6.2 9.2 10.0 2.9 10.7 1.8 11.3 4.9 2.2 4.5 5.9 6.6 2.3 3.2 7.3 13.4 2.3 7.7 12.7 3.0 7.9 3.0 6.6 6.3 29.0 13.3 8.6 11.0 20.4 16.3 6.5 3.8 38.5 11.3 12.5 6.0 13.3 9.1 14.2 28.6 4.4 34.5 2.3 5.8 10.4 9.0 12.5 3.3 27.8 19.4 8.2 15.6 3.0 8.5 58.2 54.3 98.5 71.4 132.7 78.8 203.7 84.2 80.6 66.6 195.7 85.6 80.6 25.7 90.2 176.0 87.3 123.9 73.3 22.5 23.2 21.2 29.9 21.6 22.2 22.8 22.6 22.4 22.7 22.9 22.5 43.3 16.0 41.5 11.8 83.0 90.0 87.7 177.7 99.0 29.3 139.9 173.4 53.4 60.1 93.5 68.0 10.4 69.5 46.5 64.7 133.1 95.0 50.2 53.0 35.3 36.6 71.4 22.3 9.4 126.0 147.9 31.3 120.3 73.4 23.4 52.5 29.3 69.6 84.0 11.8 8.2 100.3 97.6 43.6 49.3 46.2 20.8 49.0 110.3 2.8 61.2 39.5 63.8 9.5 14.1 189.9 81.7 24.8 47.2 142.6 150.8 148.9 75.0 29.5 6.6 24.4 45.9 105.8 80.1 185.1 180.1 72.8 53.3 37.6 73.5 152.2 TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 121.8;Excitatory neurons: 99.6;Inhibitory neurons: 93.7;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" 26.1 14.9 4.2 5.6 6.0 3.7 14.2 2.8 5.2 5.6 5.8 10.5 15.6 6.4 4.7 4.4 6.0 8.3 6.7 4.9 5.2 12.0 24.7 6.5 5.9 5.0 5.8 7.3 6.2 9.4 5.4 10.2 5.6 10.7 8.5 7.0 10.0 6.4 8.4 3.9 14.5 6.9 2.5 5.8 7.4 10.2 4.3 6.6 10.1 7.5 4.8 5.5 4.4 6.7 8.8 15.7 9.8 13.7 31.3 28.6 9.2 6.5 16.7 7.6 17.0 27.1 39.9 24.2 17.1 8.9 19.9 8.3 13.3 14.9 8.5 22.7 7.5 18.5 14.0 88.5 17.6 10.8 9.2 34.8 9.2 11.0 7.6 10.2 19.5 26.4 19.3 35.9 9.0 5.9 28.3 10.8 11.5 47.2 11.7 12.5 7.5 19.2 17.5 28.1 4.8 11.0 9.6 30.0 13.6 18.8 42.0 9.6 10.3 7.9 10.3 30.6 4.6 13.4 28.2 28.2 6.0 11.5 15.7 0.9 4.8 1.4 7.5 5.1 6.7 4.7 4.7 8.1 5.6 3.4 5.3 5.1 1.5 7.2 2.2 5.7 5.4 4.1 4.2 6.0 2.8 5.2 4.9 5.2 5.0 5.8 5.6 2.5 4.3 6.7 14.4 9.6 7.5 121.8 7.1 4.2 4.0 4.6 8.6 5.6 12.7 7.1 6.3 5.7 6.8 1.8 4.2 2.6 7.7 10.5 5.9 2.8 2.8 5.8 11.0 8.1 3.6 3.8 99.6 3.2 8.6 11.0 8.6 4.2 9.5 11.5 7.9 16.2 4.9 1.7 93.7 6.8 10.2 7.8 6.0 7.7 7.2 5.4 5.4 48.7 4.1 5.0 9.2 123.1 202.4 3.1 10.9 7.2 10.3 6.1 21.8 10.6 8.7 4.2 32.9 5.7 8.4 2.2 3.8 4.8 4.8 1.5 8.3 24.6 8.7 3.8 TMEM139 FLJ90586 ENSG00000178826 "Transmembrane protein 139" Q8IV31 7 143279957-143288048 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.8;kidney: 32.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 51.5;Ductal cells: 49.0;Proximal enterocytes: 90.7;Proximal tubular cells: 89.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 22.4;CAPAN-2: 40.8;EFO-21: 27.9;RPTEC TERT1: 70.5;SK-BR-3: 25.0;T-47d: 68.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036982, HPA036983" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Focal adhesion sites" "HPA036982: AB_2675413, HPA036983: AB_10672275" "unprognostic (2.58e-1)" "unprognostic (4.38e-1)" "unprognostic (6.62e-3)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (2.16e-3)" "unprognostic (2.83e-2)" "unprognostic (4.90e-2)" "unprognostic (1.60e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (2.89e-1)" "prognostic favorable (3.05e-5)" "unprognostic (1.73e-1)" "unprognostic (1.42e-2)" "unprognostic (2.83e-2)" "unprognostic (9.08e-3)" 1.1 2.7 1.9 2.2 6.4 0.0 3.2 6.6 3.2 8.9 2.9 5.7 33.8 1.2 1.3 0.4 6.8 7.2 3.3 1.6 4.1 32.2 9.2 5.1 0.2 10.5 6.9 0.4 8.7 6.8 1.8 5.2 8.9 0.9 4.5 0.8 4.8 3.1 0.1 1.2 19.3 0.4 5.9 0.9 2.5 3.8 5.7 0.0 7.2 0.0 0.1 1.8 0.3 13.9 22.4 1.6 0.3 0.1 0.0 0.0 14.3 0.2 0.0 0.0 0.0 5.2 40.8 0.3 27.9 0.0 1.8 18.5 0.0 9.3 0.0 0.3 0.0 0.0 2.4 3.1 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.9 0.0 1.3 0.0 0.5 0.0 1.5 1.6 1.0 0.0 0.5 1.6 0.4 0.3 0.0 70.5 5.6 0.4 0.1 1.1 25.0 0.2 0.5 68.5 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.1 0.3 0.3 0.3 0.3 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.8 0.0 0.6 0.1 1.9 6.4 6.6 3.2 1.6 4.1 10.5 6.9 8.9 5.9 5.7 13.9 0.6 16.0 5.9 0.7 0.2 0.1 2.1 2.8 0.0 0.2 8.2 15.5 2.3 27.1 5.4 51.5 0.0 30.5 0.2 28.9 35.2 49.0 14.8 16.2 1.6 0.7 3.6 0.0 0.0 4.7 5.2 0.4 3.1 17.9 0.0 2.2 1.4 16.2 1.9 0.0 0.2 6.7 0.0 0.6 0.3 13.6 0.0 0.7 5.4 0.0 1.1 7.7 0.0 0.0 5.2 30.6 23.3 0.0 0.0 1.2 90.7 89.1 3.8 0.1 0.0 0.0 0.9 0.1 0.2 0.6 0.0 6.4 0.8 0.7 12.9 1.4 TMEM163 "DKFZP566N034, SV31" ENSG00000152128 "Transmembrane protein 163" Q8TC26 2 134455759-134719000 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.3;pancreas: 27.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 36.9;Excitatory neurons: 62.2;Exocrine glandular cells: 30.8;Oligodendrocyte precursor cells: 219.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 20.3;RPTEC TERT1: 67.3;SCLC-21H: 30.2;U-937: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007224 Uncertain NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA007224: AB_2667780" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (7.25e-3)" "unprognostic (3.18e-1)" "unprognostic (1.47e-1)" "unprognostic (2.25e-1)" "unprognostic (6.08e-3)" "prognostic favorable (7.94e-4)" "unprognostic (9.05e-2)" "unprognostic (9.62e-2)" "unprognostic (6.02e-2)" "unprognostic (2.04e-1)" "unprognostic (2.60e-2)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" "unprognostic (6.75e-3)" "prognostic favorable (3.15e-4)" 3.4 8.5 13.5 5.1 13.4 0.3 1.4 18.8 13.3 0.2 5.4 1.0 0.6 0.4 0.3 0.1 2.8 9.3 6.7 12.9 15.2 1.6 0.4 14.5 10.4 18.3 20.7 0.9 27.8 0.8 13.9 3.7 15.4 0.2 0.5 4.0 3.0 0.2 0.3 0.1 1.0 0.4 16.5 1.6 7.3 6.5 28.3 2.0 0.9 0.5 16.4 12.2 0.1 23.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.2 20.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 3.5 6.7 0.1 0.1 0.3 0.0 0.6 0.1 0.0 5.2 1.1 2.3 0.0 0.1 0.1 67.3 10.0 30.2 1.1 0.0 0.0 1.6 0.1 0.0 0.0 7.0 0.0 0.4 0.0 1.5 1.6 0.0 0.0 0.0 12.6 1.3 0.0 0.0 0.0 0.3 0.0 0.4 0.4 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.2 13.5 13.4 18.8 13.3 12.9 15.2 18.3 20.7 15.4 16.5 28.3 23.0 19.3 3.2 36.9 2.6 6.7 0.0 0.0 0.0 0.0 2.7 0.2 5.1 5.4 7.2 0.0 0.0 0.0 0.1 0.9 0.1 0.0 8.5 4.8 0.3 0.2 3.5 0.0 0.4 62.2 30.8 0.4 0.7 20.9 1.0 0.0 0.6 0.4 0.3 5.0 1.7 23.5 0.4 0.0 1.3 0.0 3.8 0.0 2.7 0.0 14.0 2.6 1.0 5.2 219.7 13.0 12.6 0.1 0.4 0.3 0.0 0.0 0.3 0.0 5.7 0.0 0.5 0.4 2.1 1.6 0.0 0.4 0.1 0.7 1.9 0.1 2.5 TMEM164 "FLJ22679, RP13-360B22.2" ENSG00000157600 "Transmembrane protein 164" Q5U3C3 X 110002631-110182734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Distal enterocytes: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 59.7" "Lineage enriched" "Detected in many" 18 "granulocytes: 59.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038784 Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "Cell Junctions" "HPA038784: AB_10670790" "unprognostic (2.14e-3)" "unprognostic (3.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.65e-3)" "unprognostic (7.94e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (8.17e-6)" "unprognostic (9.85e-3)" "unprognostic (5.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-2)" "unprognostic (3.95e-1)" "unprognostic (7.66e-2)" "prognostic favorable (3.14e-4)" "unprognostic (1.76e-1)" "unprognostic (1.81e-2)" "unprognostic (4.19e-3)" 16.9 10.3 11.4 9.6 11.8 19.0 12.3 6.8 9.7 5.5 14.3 18.8 21.5 5.3 6.0 13.8 8.1 5.1 22.7 9.0 12.1 11.1 2.0 17.9 6.7 13.5 13.0 13.8 25.4 8.3 9.6 5.2 11.2 8.9 21.2 3.6 9.8 14.4 27.5 20.3 19.2 6.9 8.2 8.4 14.0 1.9 12.3 12.6 13.8 19.3 8.0 5.8 6.8 8.6 10.8 24.3 19.5 12.8 23.7 17.3 11.9 5.3 12.4 11.0 7.1 19.1 16.6 8.6 35.2 8.3 27.1 15.6 17.1 27.9 10.8 23.9 11.7 58.5 13.0 8.1 13.9 26.1 80.1 24.0 48.4 19.9 27.2 30.2 21.8 15.2 18.4 10.2 19.7 21.6 27.4 33.1 17.5 36.9 17.3 12.4 15.1 7.2 17.5 11.3 18.2 20.3 34.0 33.1 15.9 18.1 9.6 25.7 49.0 9.3 6.8 11.0 7.7 5.9 7.9 6.9 24.3 32.0 25.3 59.7 3.3 14.2 0.6 2.9 1.6 0.2 0.7 0.6 2.7 0.6 0.4 0.5 16.3 2.3 1.8 0.5 1.0 1.8 11.4 11.8 6.8 9.7 9.0 12.1 13.5 13.0 11.2 8.2 12.3 8.6 2.9 3.2 36.1 84.5 3.7 4.8 3.7 4.7 4.6 1.2 11.7 9.1 21.3 11.5 6.9 16.5 2.1 2.7 3.5 53.0 3.9 4.6 0.5 6.7 3.8 6.0 27.6 14.5 22.9 11.4 6.3 3.1 7.7 10.7 3.8 4.3 6.4 1.7 13.6 0.0 31.4 12.7 10.2 25.1 9.4 1.3 1.8 12.5 1.8 24.4 28.1 1.0 4.1 34.2 7.6 13.5 15.0 1.5 1.6 9.0 31.9 3.3 5.4 1.3 0.0 6.4 4.1 0.2 0.3 10.4 8.0 2.7 5.2 3.8 21.2 12.3 TMEM203 "HBEBP1, MGC14327" ENSG00000187713 "Transmembrane protein 203" Q969S6 9 137204082-137205648 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.31e-1)" "unprognostic (2.65e-2)" "unprognostic (4.53e-2)" "unprognostic (8.72e-2)" "unprognostic (1.10e-1)" "unprognostic (6.54e-2)" "unprognostic (2.72e-2)" "unprognostic (1.78e-1)" "unprognostic (1.43e-1)" "unprognostic (7.16e-2)" "prognostic favorable (4.78e-6)" "unprognostic (2.94e-1)" "prognostic favorable (1.50e-5)" "unprognostic (3.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.04e-2)" "unprognostic (1.19e-1)" 25.7 32.6 32.8 17.2 33.6 10.9 25.5 33.8 36.8 28.1 33.1 30.2 22.2 29.9 26.4 31.4 24.2 16.4 45.9 32.9 33.4 33.2 49.2 20.5 27.0 33.6 33.6 27.7 26.2 30.7 25.6 15.9 33.4 27.1 18.2 16.4 26.8 21.8 49.7 43.6 28.5 16.9 32.8 30.4 30.1 19.1 34.9 20.3 25.1 45.9 22.7 27.8 27.6 33.0 38.0 39.3 36.5 60.7 53.1 41.1 43.6 48.4 46.6 55.1 41.1 32.6 33.3 39.0 45.7 42.2 53.0 72.6 45.3 48.1 32.1 71.0 43.5 27.0 45.5 37.4 44.3 63.1 26.8 39.6 75.4 36.0 47.4 36.8 35.8 50.5 64.2 44.4 43.2 65.2 50.5 54.6 60.8 72.4 63.2 54.2 51.1 78.2 46.5 27.2 48.3 47.3 38.6 48.8 39.2 25.0 68.8 50.6 32.0 56.3 30.1 63.6 55.1 23.8 80.0 49.5 43.5 46.3 47.3 4.7 3.8 4.1 5.2 4.3 6.4 8.3 5.8 6.5 4.6 4.5 8.7 6.0 1.9 7.5 3.9 4.8 4.0 2.6 32.8 33.6 33.8 36.8 32.9 33.4 33.6 33.6 33.4 32.8 34.9 33.0 23.2 9.6 6.8 4.6 21.4 17.6 22.7 7.0 23.9 33.6 29.6 33.8 13.5 40.0 7.9 31.3 4.2 30.5 23.7 15.9 52.8 49.4 3.5 15.3 24.2 20.7 16.3 29.8 5.7 42.0 26.3 22.3 14.8 13.3 5.7 31.7 21.4 41.1 29.3 32.0 6.2 13.4 10.2 27.1 13.2 9.4 22.1 20.8 24.9 5.6 54.2 58.8 24.7 2.5 6.1 41.7 10.8 20.7 13.3 37.2 18.5 59.2 4.9 25.7 13.1 19.5 32.5 18.6 15.9 28.5 27.3 19.4 24.4 36.2 18.6 17.9 TMEM236 "bA162I21.2, bA16O1.2, FAM23A, FAM23B" ENSG00000148483 "Transmembrane protein 236" Q5W0B7 10 17752201-17800868 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 33.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 81.1;Enteroendocrine cells: 23.4;Intestinal goblet cells: 28.8;Paneth cells: 48.1;Proximal enterocytes: 96.5;Undifferentiated cells: 19.0" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.7;pancreatic cancer: 0.5;stomach cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "MOLT-4: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045096 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA045096: AB_2732516" "unprognostic (4.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.88e-3)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (3.36e-2)" "unprognostic (2.52e-3)" "unprognostic (1.37e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (5.06e-3)" "unprognostic (1.75e-1)" "unprognostic (1.62e-2)" "unprognostic (1.72e-1)" "unprognostic (3.43e-2)" "unprognostic (3.16e-2)" "unprognostic (1.54e-2)" 0.7 0.6 0.3 1.7 0.3 0.5 0.4 0.8 0.5 0.5 0.4 14.1 21.8 0.3 0.2 0.3 0.2 0.4 0.3 0.3 0.1 0.2 0.1 0.7 0.3 0.1 0.0 0.3 0.5 0.1 0.0 1.5 0.2 0.1 14.0 0.3 0.1 0.2 0.3 0.3 33.5 1.0 0.0 0.3 0.4 0.2 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.7 0.2 0.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.3 0.3 0.2 0.0 0.2 0.9 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.1 0.2 0.1 0.2 10.3 0.1 0.1 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.0 0.4 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.3 0.8 0.5 0.3 0.1 0.1 0.0 0.2 0.0 0.1 0.7 0.2 0.0 0.5 0.0 0.2 0.1 0.5 0.0 0.0 0.3 7.3 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.1 81.1 0.0 0.1 1.1 0.1 0.1 0.2 23.4 0.4 0.4 0.9 0.2 0.2 0.0 0.5 1.3 0.1 1.1 0.0 7.2 0.0 0.4 28.8 0.0 4.8 0.8 1.1 0.0 5.9 0.0 3.7 0.0 0.1 0.0 0.0 0.6 0.7 48.1 0.0 0.0 0.4 96.5 0.0 0.0 0.9 0.0 0.7 0.3 0.4 0.1 0.2 0.0 0.3 0.4 0.2 19.0 0.6 TMEM254 "bA369J21.6, C10orf57, FLJ13263" ENSG00000133678 "Transmembrane protein 254" Q8TBM7 10 80078646-80092557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029105, HPA072613" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA029105: AB_2672909, HPA072613: AB_2732205" "unprognostic (9.40e-2)" "unprognostic (1.76e-1)" "unprognostic (9.52e-2)" "unprognostic (5.74e-3)" "unprognostic (5.39e-2)" "unprognostic (6.04e-2)" "unprognostic (3.66e-1)" "unprognostic (3.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.87e-3)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (7.65e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (3.45e-3)" "unprognostic (5.96e-2)" 15.2 11.9 7.9 11.1 8.3 9.4 26.5 7.3 8.3 16.0 7.0 22.6 16.3 10.7 62.1 39.5 28.0 14.0 5.7 8.0 7.0 14.8 52.8 9.4 10.4 8.0 8.7 13.0 19.0 16.5 4.4 15.6 8.5 43.1 22.3 11.2 16.6 14.2 4.4 72.3 15.4 10.4 8.3 7.8 15.0 15.5 7.5 15.4 14.8 2.9 14.6 12.4 22.7 9.3 14.4 13.8 20.0 17.2 27.1 29.7 33.4 13.5 9.3 9.0 9.7 10.6 43.5 11.0 22.1 16.9 9.3 15.2 8.9 11.5 10.0 17.5 16.5 3.0 3.8 14.3 11.2 12.8 13.0 20.3 48.6 8.9 7.3 20.6 7.7 9.1 7.9 22.9 9.4 29.8 10.7 9.9 11.0 12.6 43.2 13.2 2.8 9.7 13.5 11.9 8.0 12.1 12.6 31.4 13.3 14.8 45.1 9.1 12.1 7.8 12.8 12.0 8.0 15.8 24.7 0.8 17.8 13.6 6.6 57.3 25.0 13.0 18.1 28.6 22.3 21.3 20.2 18.8 20.7 14.3 33.8 22.6 2.8 17.5 31.5 23.1 27.2 20.5 7.9 8.3 7.3 8.3 8.0 7.0 8.0 8.7 8.5 8.3 7.5 9.3 4.6 9.6 9.6 17.6 7.3 8.2 5.9 9.7 5.2 7.9 22.6 17.5 4.4 12.8 13.7 9.2 16.7 40.9 3.8 9.0 21.5 15.7 10.5 37.6 10.0 5.4 8.4 5.9 17.2 8.7 37.2 7.6 11.2 10.5 5.7 12.9 5.7 33.4 19.4 16.8 16.4 23.7 8.2 10.3 5.8 7.5 9.3 8.5 3.6 4.7 15.2 15.7 12.3 8.5 14.8 10.3 15.3 11.7 5.2 15.6 19.6 23.1 40.2 13.3 13.1 2.6 7.1 36.8 8.7 20.9 24.0 22.7 6.9 11.2 18.1 8.4 TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.0;Endothelial cells: 81.5;granulocytes: 39.3;Hepatic stellate cells: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Cell line enhanced" "Detected in many" "HMC-1: 28.6;HUVEC TERT2: 38.8;PC-3: 39.3;RPMI-8226: 25.1;TIME: 35.9;U-87 MG: 40.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" 14.2 6.1 1.3 3.7 1.3 0.7 10.6 1.1 2.2 10.1 2.1 4.0 1.6 8.4 0.3 3.9 8.1 3.6 6.6 1.6 3.7 10.1 3.4 13.2 2.4 2.1 1.3 4.3 3.1 1.6 3.5 1.0 1.7 7.0 1.4 0.4 4.2 2.2 2.9 4.2 4.8 5.0 1.4 8.2 4.3 3.3 1.9 0.8 11.2 3.9 1.8 7.5 7.1 1.5 10.3 0.0 0.6 0.0 2.8 0.0 0.1 4.8 10.7 5.5 3.5 0.4 0.2 0.2 0.1 7.7 12.5 1.5 1.1 0.7 2.3 0.1 0.9 0.3 0.4 0.0 1.4 2.9 28.6 1.8 2.3 11.7 4.6 15.7 38.8 0.6 0.1 0.2 12.0 0.2 1.5 0.9 1.0 1.6 39.3 1.8 0.8 25.1 5.4 0.5 2.2 5.1 0.2 1.5 0.1 1.0 0.6 8.2 35.9 1.6 10.3 0.6 1.7 0.0 0.0 1.9 40.6 2.7 0.3 31.2 5.4 0.7 0.0 5.5 0.0 0.9 0.0 0.0 1.5 2.8 0.0 0.0 2.7 0.0 4.0 0.0 0.0 1.4 1.3 1.3 1.1 2.2 1.6 3.7 2.1 1.3 1.7 1.4 1.9 1.5 65.0 6.4 4.8 2.3 1.9 5.9 1.2 0.9 1.2 0.9 1.1 1.7 9.1 0.0 0.2 1.8 0.0 0.1 0.3 0.0 1.9 8.2 0.8 0.3 0.8 81.5 1.2 3.2 2.7 1.7 0.1 4.7 0.0 0.2 39.3 2.3 105.0 0.7 12.9 0.0 0.1 0.2 0.0 17.4 14.6 1.1 7.8 16.3 8.8 7.5 3.4 0.5 0.0 0.0 0.6 1.3 0.1 3.0 1.4 1.7 0.0 0.1 0.5 0.8 6.6 0.9 3.6 5.1 19.1 0.2 4.7 0.0 1.8 2.1 0.3 1.0 TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 219.8;skin 1: 64.7;vagina: 80.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 104.7;Cytotrophoblasts: 128.3;Macrophages: 121.3;Squamous epithelial cells: 116.5;Suprabasal keratinocytes: 201.9;Syncytiotrophoblasts: 656.6;Urothelial cells: 157.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3;urothelial cancer: 12.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 244.9;hTCEpi: 56.1;hTERT-HME1: 68.0;RT4: 36.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044165, HPA073122" Enhanced Approved Cytosol NA NA 2500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA044165: AB_10961279, HPA073122: " "unprognostic (2.51e-3)" "unprognostic (1.96e-2)" "unprognostic (2.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.27e-1)" "unprognostic (1.92e-1)" "unprognostic (5.15e-4)" "unprognostic (5.96e-2)" "unprognostic (3.15e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-3)" "unprognostic (2.47e-1)" "unprognostic (1.20e-3)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (6.77e-2)" 0.1 0.1 0.4 0.0 0.4 3.3 3.2 0.5 0.6 42.1 0.3 0.0 0.1 0.1 1.3 219.8 3.1 0.1 4.2 0.5 0.3 0.2 0.3 2.1 0.1 0.4 0.3 0.1 0.1 3.2 0.2 15.9 0.3 3.7 0.0 0.1 27.3 2.5 1.3 64.7 0.0 0.1 0.1 1.8 0.2 0.8 0.4 1.5 0.1 0.6 25.9 15.2 80.1 0.3 26.6 0.1 0.0 0.1 0.0 0.0 22.4 0.2 1.1 1.3 1.4 1.0 4.1 0.1 0.2 0.0 0.6 7.6 0.0 244.9 5.1 0.2 0.0 1.9 0.2 0.8 0.0 0.0 0.0 0.0 56.1 0.0 68.0 0.4 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 0.0 0.2 4.3 0.0 1.6 0.0 1.6 36.0 0.2 0.2 0.1 31.3 0.0 4.6 2.8 0.7 0.0 0.0 1.6 0.0 2.1 0.3 0.1 0.4 0.1 0.0 0.0 1.6 0.9 1.1 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 6.0 0.0 0.0 0.8 0.0 32.9 0.4 0.4 0.5 0.6 0.5 0.3 0.4 0.3 0.3 0.1 0.4 0.3 0.1 0.0 0.0 0.3 0.3 64.2 104.7 71.7 17.6 0.0 1.5 5.6 4.7 0.0 39.4 1.8 0.0 128.3 0.0 0.1 0.0 0.5 0.8 2.9 0.0 1.8 0.0 0.0 0.3 0.0 14.7 1.8 0.0 0.1 0.0 0.0 2.2 0.7 10.8 0.0 0.3 0.0 12.2 4.8 7.3 2.0 0.3 121.3 10.6 0.0 2.6 0.0 2.1 0.0 0.2 2.2 0.0 0.0 0.0 53.5 0.0 0.0 55.0 0.0 0.0 0.1 3.6 0.7 6.8 116.5 201.9 656.6 1.0 0.2 0.0 157.9 TMEM41A MGC15397 ENSG00000163900 "Transmembrane protein 41A" Q96HV5 3 185476496-185499057 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 200.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059101, HPA059790" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059101: AB_2683905, HPA059790: AB_2684125" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (6.70e-6)" "unprognostic (2.67e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.84e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.63e-2)" "unprognostic (2.56e-2)" "unprognostic (3.73e-1)" "unprognostic (3.68e-1)" "unprognostic (1.46e-2)" "unprognostic (1.02e-2)" 9.0 27.2 9.6 5.4 9.3 11.0 10.2 9.7 11.0 10.0 8.9 7.9 26.4 8.7 11.2 23.6 9.2 7.6 9.9 9.0 9.4 14.7 20.5 10.6 7.4 9.4 11.6 14.1 9.7 8.7 5.7 8.4 9.2 10.2 8.9 7.5 12.0 8.3 9.8 19.9 24.1 7.4 9.8 12.5 10.3 9.3 12.1 7.8 7.0 16.4 12.6 10.8 14.6 10.9 43.6 15.4 10.1 12.5 15.6 16.8 29.6 16.3 14.3 20.2 14.6 40.5 16.7 13.4 30.5 15.3 28.5 29.4 28.1 17.5 20.4 22.6 25.8 23.3 8.6 41.2 17.5 25.3 12.5 15.7 25.6 18.3 20.9 12.7 15.6 16.8 42.1 32.4 13.0 16.8 15.6 14.5 16.8 34.1 24.1 15.5 15.6 24.6 17.4 31.4 10.1 13.1 14.1 35.8 25.7 14.4 42.8 19.6 11.4 11.9 15.0 25.2 34.5 47.2 78.0 26.5 18.2 15.1 14.6 14.0 8.2 7.2 16.3 9.4 21.0 17.5 16.7 18.1 9.3 15.6 18.2 19.8 2.8 12.2 12.2 21.7 15.3 9.2 9.6 9.3 9.7 11.0 9.0 9.4 9.4 11.6 9.2 9.8 12.1 10.9 12.1 9.6 30.5 7.2 16.7 53.0 42.8 29.5 50.7 22.4 38.2 20.6 12.6 24.3 24.9 20.2 18.8 27.5 18.3 23.3 7.9 33.4 0.7 17.7 14.5 19.8 18.6 16.4 8.1 56.0 23.5 18.0 36.2 38.0 8.8 50.2 17.2 40.9 19.6 16.8 9.8 28.3 16.2 14.2 17.3 2.8 14.3 12.5 8.8 2.8 65.9 11.4 11.3 20.1 7.6 50.3 17.0 13.5 20.9 64.2 200.8 23.2 9.6 28.6 19.7 16.8 16.5 22.1 14.3 113.0 84.7 46.0 18.5 82.6 45.6 93.4 TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.2;Hepatic stellate cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.7;NK-cell: 8.1" "Group enriched" "Detected in many" 10 "granulocytes: 3.7;NK-cells: 8.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043718 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA043718: AB_10794662" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (8.31e-3)" "unprognostic (4.53e-2)" "unprognostic (2.78e-3)" "unprognostic (9.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.70e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (6.55e-13)" "unprognostic (1.23e-2)" "unprognostic (3.36e-1)" "unprognostic (1.65e-3)" "unprognostic (5.66e-2)" 10.3 2.9 9.8 2.3 11.7 5.2 8.9 7.8 12.4 6.9 7.1 11.0 2.7 5.6 13.7 5.6 5.4 4.5 9.6 10.3 10.1 6.0 3.4 11.3 3.0 9.9 9.7 4.9 3.5 0.9 2.6 7.4 10.0 5.2 7.2 0.6 7.7 2.2 3.2 3.6 6.8 3.2 8.8 9.3 4.9 2.2 10.5 2.0 5.6 2.3 1.6 5.3 5.9 9.2 11.1 9.1 13.4 14.2 4.8 16.2 11.8 8.2 15.3 6.8 10.8 5.0 21.8 2.0 38.9 10.0 20.3 12.6 4.5 6.4 4.6 18.1 6.3 12.4 10.6 3.8 8.7 3.9 18.9 10.0 6.8 15.4 6.8 32.8 28.2 12.1 3.4 0.5 22.9 10.1 5.9 9.9 6.9 11.1 14.8 11.5 8.4 0.3 7.2 6.3 3.7 7.7 6.1 1.9 12.6 5.6 9.0 8.5 33.7 20.8 7.6 6.4 11.2 1.5 1.2 4.0 31.4 15.0 10.4 3.7 0.2 0.2 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.2 0.0 0.2 0.4 8.1 0.3 0.4 0.0 0.0 9.8 11.7 7.8 12.4 10.3 10.1 9.9 9.7 10.0 8.8 10.5 9.2 22.0 0.0 2.3 3.3 2.1 0.5 3.3 4.9 1.8 0.9 2.8 2.3 1.7 1.5 6.0 5.5 2.1 9.5 1.7 31.2 0.0 5.7 0.6 2.3 3.7 23.8 6.0 4.0 12.7 4.9 4.0 6.0 22.4 2.0 17.7 10.6 53.2 0.6 3.5 0.0 5.4 25.2 6.1 1.3 3.4 0.3 3.1 1.5 1.8 12.2 0.1 0.5 2.1 2.5 1.5 14.9 21.0 1.9 1.3 6.0 3.9 0.4 7.5 0.6 6.6 1.8 3.6 0.5 6.5 2.4 0.6 8.8 1.9 6.0 21.0 6.3 TMEM45A "DERP7, FLJ10134" ENSG00000181458 "Transmembrane protein 45A" Q9NWC5 3 100492619-100577444 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skin 1: 475.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 425.3;Club cells: 841.5;Early spermatids: 207.3;Suprabasal keratinocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 406.9;ASC TERT1: 118.3;HSkMC: 125.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA062101 Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "HPA062101: AB_2684682" "unprognostic (5.92e-3)" "unprognostic (5.44e-2)" "unprognostic (2.11e-1)" "unprognostic (1.43e-3)" "unprognostic (7.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.18e-11)" "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.02e-5)" "unprognostic (2.68e-2)" 19.4 18.1 1.4 11.7 3.3 2.0 42.8 1.7 2.5 38.4 2.3 10.3 3.6 18.3 3.2 16.5 20.9 18.9 21.9 1.5 1.8 3.7 99.0 13.1 2.6 1.9 1.9 11.9 23.3 2.7 22.9 40.9 1.8 9.1 6.6 1.7 26.9 6.3 3.2 475.1 6.4 25.4 1.7 5.0 7.0 13.3 1.9 1.6 9.1 2.5 50.7 19.5 79.5 2.1 28.6 2.0 2.7 9.6 406.9 118.3 0.3 66.9 62.0 9.4 84.8 2.5 0.6 0.0 32.6 44.1 24.6 31.9 2.4 13.0 23.4 7.2 8.4 23.9 9.3 8.0 25.7 0.4 1.5 125.4 7.4 17.1 25.4 39.0 3.5 0.0 0.6 3.2 22.6 0.3 0.1 0.7 3.2 0.0 16.8 0.0 23.3 0.4 0.6 1.0 2.9 19.4 16.4 8.5 7.3 18.2 0.8 13.6 9.3 62.9 44.3 0.5 15.2 53.8 32.9 0.1 49.7 1.9 42.6 0.0 0.9 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.6 1.4 3.3 1.7 2.5 1.5 1.8 1.9 1.9 1.8 1.7 1.9 2.1 1.6 60.9 61.4 0.7 3.0 94.6 5.4 425.3 9.6 3.2 19.1 8.9 2.5 1.5 841.5 0.0 0.0 2.6 0.4 0.2 0.0 7.5 207.3 3.0 79.1 8.9 1.2 1.3 0.8 14.9 46.3 56.3 2.0 2.0 65.0 10.7 15.0 137.1 5.8 8.4 2.4 2.0 63.1 6.5 25.4 25.4 16.1 6.6 23.2 13.1 1.1 3.5 0.0 16.1 11.8 6.5 2.6 27.8 26.8 3.1 0.3 0.2 121.0 0.9 6.6 22.8 56.6 1.5 3.3 5.4 254.9 7.5 6.4 26.7 0.1 4.4 TMEM54 CAC-1 ENSG00000121900 "Transmembrane protein 54" Q969K7 1 32894594-32901438 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1231.3;Intestinal goblet cells: 357.2;Paneth cells: 800.1;Proximal enterocytes: 418.6;Undifferentiated cells: 355.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 198.9;OE19: 242.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060864, HPA061992" Approved Approved Vesicles NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA060864: , HPA061992: AB_2684652" "unprognostic (2.67e-1)" "unprognostic (2.57e-2)" "unprognostic (2.55e-1)" "unprognostic (4.98e-2)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.42e-2)" "unprognostic (3.48e-2)" "unprognostic (9.43e-2)" "unprognostic (6.82e-3)" "unprognostic (2.13e-2)" "unprognostic (9.06e-2)" "unprognostic (3.12e-2)" "unprognostic (3.40e-2)" 19.2 15.6 68.2 39.9 64.2 0.0 24.6 61.3 98.4 59.0 52.8 268.0 116.0 40.4 26.6 145.3 25.5 62.0 18.7 64.1 70.0 44.3 14.9 26.8 4.6 70.5 68.8 20.3 31.8 49.5 22.6 18.4 64.8 58.2 113.2 4.2 54.0 22.9 6.9 116.0 123.1 21.3 67.8 13.2 108.0 11.9 65.5 2.4 47.8 4.9 13.0 51.1 78.6 66.4 133.3 33.9 0.0 32.0 59.1 35.4 119.9 20.0 29.2 43.1 55.2 84.7 198.9 0.0 57.1 24.8 55.2 80.0 28.6 107.4 12.8 158.3 6.4 0.2 11.3 4.5 42.9 0.4 2.0 30.5 96.2 66.1 18.1 29.1 19.3 13.0 18.7 0.1 22.7 135.6 0.1 2.6 10.3 242.7 60.8 17.7 52.2 0.6 16.2 159.8 1.8 17.1 14.4 82.1 44.0 19.3 89.3 24.2 39.9 42.3 47.5 95.9 40.8 5.2 12.4 15.8 30.1 3.3 61.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.2 64.2 61.3 98.4 64.1 70.0 70.5 68.8 64.8 67.8 65.5 66.4 6.4 19.2 27.6 3.9 6.6 20.4 92.3 36.9 20.5 8.2 82.0 61.0 4.7 97.2 36.9 47.8 4.2 42.8 1.3 1231.3 27.4 150.2 43.4 7.5 16.1 12.3 60.7 0.0 3.3 202.4 149.1 22.9 160.0 14.3 5.7 11.8 18.9 3.7 8.4 0.0 2.9 357.2 12.2 1.0 6.5 32.3 19.9 3.7 14.2 0.0 3.1 33.7 0.0 3.5 2.6 166.3 800.1 24.5 1.6 160.9 418.6 84.9 14.0 10.3 6.6 8.5 20.6 10.9 8.8 65.0 63.6 64.3 3.3 2.4 355.8 193.3 TMEM63B "C6orf110, dJ421H19.2, DKFZp434P0531" ENSG00000137216 "Transmembrane protein 63B" Q5T3F8 6 44126914-44155519 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 87.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 163.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029249, HPA029250, HPA029251" Uncertain Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Actin filaments" "HPA029249: AB_2672965, HPA029250: AB_2672966, HPA029251: AB_2672967" "unprognostic (8.83e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-3)" "unprognostic (3.61e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.97e-3)" "unprognostic (1.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-1)" "unprognostic (8.60e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.67e-2)" "unprognostic (6.12e-3)" "unprognostic (3.15e-1)" 12.4 19.6 18.1 9.5 18.9 17.9 12.6 18.9 24.7 17.8 15.1 24.6 17.1 11.4 12.1 34.6 10.7 12.8 26.5 25.1 21.0 17.1 39.2 38.3 5.8 19.9 17.5 12.1 12.6 20.2 15.6 13.6 20.4 17.4 19.4 31.6 20.9 8.6 51.6 41.4 18.5 9.9 15.7 9.8 25.4 31.0 19.8 8.6 16.2 21.2 8.6 18.8 23.2 18.3 41.7 23.1 21.1 34.6 32.3 18.6 34.6 17.0 22.8 18.7 17.7 16.1 15.7 7.2 25.5 25.3 30.1 37.8 25.6 62.6 12.3 20.6 19.5 20.8 17.2 49.1 22.2 4.6 19.2 24.8 55.5 26.2 16.7 37.8 18.9 15.3 67.7 11.2 22.0 42.7 4.6 10.3 11.4 163.7 11.2 5.8 14.0 13.2 52.2 44.5 24.3 18.8 15.2 35.5 35.8 26.0 40.1 11.6 21.8 23.8 27.0 17.9 20.7 14.0 11.1 8.8 35.9 6.6 30.7 0.2 0.4 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.2 0.2 0.4 0.2 18.1 18.9 18.9 24.7 25.1 21.0 19.9 17.5 20.4 15.7 19.8 18.3 7.2 16.0 19.7 17.6 3.3 13.6 14.9 41.3 21.1 18.4 11.2 9.3 3.8 10.0 25.1 11.0 16.7 14.1 4.2 75.1 1.9 17.0 72.9 10.6 8.9 6.9 18.6 28.4 26.3 15.2 16.6 11.0 45.9 25.1 0.0 11.0 11.7 43.4 26.4 16.8 28.4 32.4 30.5 11.7 11.4 87.6 11.8 9.1 7.2 15.0 8.5 9.4 5.2 21.6 12.1 32.5 45.7 9.1 6.4 21.9 32.7 10.8 15.7 27.6 6.6 10.4 12.0 2.1 14.7 19.4 18.3 20.0 5.5 7.1 24.3 29.4 TMEM79 "FLJ16057, FLJ32254, MATT, MGC13102" ENSG00000163472 "Transmembrane protein 79" Q9BSE2 1 156282935-156293185 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 132.4;skin 1: 89.9;vagina: 59.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 24.1;Squamous epithelial cells: 59.9;Suprabasal keratinocytes: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 30.2;SK-BR-3: 26.7;T-47d: 28.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA055214 Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center" "HPA055214: AB_2682741" "unprognostic (3.12e-1)" "unprognostic (2.96e-1)" "unprognostic (1.26e-1)" "unprognostic (8.17e-2)" "unprognostic (5.51e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (6.37e-2)" "unprognostic (2.44e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (4.31e-7)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (3.98e-2)" "unprognostic (2.37e-1)" 2.1 2.8 5.5 1.5 6.3 2.9 4.5 6.2 7.5 34.5 5.1 2.4 2.6 2.4 2.6 132.4 2.5 1.8 1.8 5.2 5.7 2.4 3.6 1.9 2.9 6.2 6.2 2.4 2.1 6.0 3.7 1.6 6.0 28.4 1.3 1.7 23.5 2.6 2.9 89.9 2.7 1.2 5.8 3.8 2.9 2.0 6.1 3.6 2.2 0.7 10.9 6.9 59.4 7.8 12.5 7.2 2.4 4.7 1.8 1.8 5.9 3.5 1.4 6.2 2.4 8.5 3.4 2.2 7.6 0.9 2.2 10.8 2.8 5.1 2.7 8.3 3.9 2.3 3.3 2.5 3.3 2.6 3.3 1.7 30.2 4.6 4.7 4.4 1.4 8.2 10.5 14.8 2.9 14.1 7.3 4.0 3.6 9.0 5.7 8.5 2.3 5.0 1.3 3.0 4.3 4.7 4.3 26.7 7.0 2.9 28.3 7.4 3.4 11.5 3.8 4.2 9.5 11.3 13.0 5.2 8.0 6.0 8.8 0.0 2.0 3.0 1.7 0.7 1.8 1.7 1.5 1.8 1.6 2.2 2.0 2.4 3.7 1.7 1.3 2.0 2.1 1.7 5.5 6.3 6.2 7.5 5.2 5.7 6.2 6.2 6.0 5.8 6.1 7.8 1.8 3.2 1.5 8.8 3.9 13.3 1.4 24.1 9.1 3.0 10.0 6.5 1.2 2.8 14.3 1.8 2.1 7.7 3.6 2.4 1.9 2.5 0.1 3.7 2.4 2.0 3.0 0.8 1.8 3.3 1.8 2.1 1.5 6.7 0.0 3.1 2.2 2.4 3.4 8.4 2.2 2.9 10.2 2.5 1.8 0.3 1.5 1.4 5.4 3.7 4.4 1.5 1.0 2.5 5.8 4.5 2.1 0.7 1.6 10.7 4.3 1.6 4.2 2.2 0.0 1.0 1.9 1.3 2.1 59.9 33.1 7.4 3.2 2.9 3.1 6.4 TMLHE "BBOX2, FLJ10727, TMLH, XAP130" ENSG00000185973 "Trimethyllysine hydroxylase, epsilon" Q9NVH6 X 155489011-155719098 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 51.5;Oligodendrocyte precursor cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034589, HPA040331" Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA034589: AB_10670571, HPA040331: AB_2676929" "unprognostic (1.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.04e-1)" "unprognostic (5.41e-2)" "unprognostic (6.66e-3)" "unprognostic (1.10e-3)" "unprognostic (6.50e-2)" "unprognostic (1.00e-1)" "unprognostic (3.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.20e-3)" "unprognostic (6.97e-2)" "prognostic favorable (3.68e-6)" "unprognostic (1.69e-1)" "unprognostic (5.74e-2)" "unprognostic (2.73e-1)" "unprognostic (7.75e-2)" 11.7 10.2 7.1 6.6 7.4 8.4 11.3 9.0 8.0 11.3 8.1 11.6 11.8 9.4 10.4 10.3 9.9 8.0 25.3 6.7 7.7 16.7 18.8 5.6 7.0 8.5 8.2 12.0 9.5 18.9 5.4 8.4 8.5 6.6 12.5 10.9 12.7 9.7 32.0 5.9 11.2 12.3 8.3 8.7 9.1 2.9 7.3 8.9 10.5 33.4 7.6 8.2 6.6 9.8 25.0 11.9 9.8 28.6 11.8 18.1 0.0 9.9 14.6 12.3 32.4 8.7 13.9 0.0 38.9 17.6 28.2 13.4 21.2 9.7 13.9 10.3 14.3 11.3 19.5 10.2 16.4 10.5 7.6 19.5 20.0 13.6 20.8 18.2 19.5 15.5 15.8 9.0 20.5 9.3 12.8 11.8 3.0 21.6 0.1 12.7 15.5 9.4 15.0 8.5 9.2 13.7 9.3 0.5 11.2 10.5 10.6 11.9 16.5 10.3 9.7 20.4 12.4 11.0 12.6 9.6 12.4 16.4 9.6 3.4 12.6 14.7 4.6 14.9 3.5 8.1 5.0 3.9 13.1 10.6 6.5 5.7 18.2 6.2 21.5 6.1 5.5 5.8 7.1 7.4 9.0 8.0 6.7 7.7 8.5 8.2 8.5 8.3 7.3 9.8 6.7 0.0 2.3 27.1 10.1 5.2 12.1 14.4 9.6 4.0 5.2 7.5 7.2 7.2 9.7 9.2 0.0 8.8 6.5 7.9 23.5 10.7 0.0 6.8 7.4 6.2 6.1 14.3 22.2 7.6 6.8 10.2 9.2 7.3 10.1 8.1 4.2 12.0 12.4 0.0 29.5 7.3 4.1 16.1 10.4 0.5 8.4 12.1 12.4 51.5 13.1 7.6 10.3 47.7 25.5 8.5 7.3 5.7 5.6 4.3 17.4 17.0 9.5 5.4 0.0 5.9 9.5 0.3 2.5 7.6 4.1 6.7 8.0 10.5 6.5 11.0 TMPRSS3 "DFNB10, DFNB8" ENSG00000160183 "Transmembrane serine protease 3" P57727 21 42371887-42396091 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 23.7;stomach 1: 14.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 17.7;Cholangiocytes: 24.3;Ductal cells: 16.1;Endometrial ciliated cells: 17.1;Gastric mucus-secreting cells: 23.4;Ionocytes: 16.2;Muller glia cells: 20.4;Respiratory ciliated cells: 39.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 16.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.1" "Lineage enriched" "Detected in single" 6 "T-cells: 3.1" "Cell line enriched" "Detected in some" 4 "U-266/84: 274.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: U-266 - Nucleosome" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (8.47e-3)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.85e-1)" "unprognostic (2.45e-3)" "unprognostic (3.97e-2)" "unprognostic (1.43e-1)" "unprognostic (8.17e-2)" "unprognostic (9.62e-2)" "unprognostic (4.81e-2)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.66e-2)" "unprognostic (2.73e-1)" "unprognostic (8.00e-2)" "unprognostic (1.33e-1)" 0.5 0.3 3.8 0.2 4.0 0.1 8.7 4.0 3.7 6.3 2.0 0.2 1.3 0.7 0.0 0.2 23.7 8.6 0.0 3.4 4.1 2.4 0.5 3.4 0.5 4.9 4.7 0.0 3.0 0.0 1.5 0.2 3.7 0.4 0.1 3.9 9.2 0.4 0.1 0.1 1.1 0.0 3.5 0.4 14.5 0.0 4.7 0.9 2.9 0.0 0.4 1.0 0.0 2.7 4.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 32.9 0.0 66.2 26.5 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.6 0.0 14.0 0.0 1.5 3.5 0.0 0.0 1.0 0.4 0.0 0.0 0.0 2.8 1.5 0.0 0.0 33.9 1.6 0.0 0.0 3.2 0.3 0.1 0.0 1.7 0.0 0.2 0.7 274.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 3.1 0.0 1.7 1.8 0.0 0.0 0.3 0.9 0.3 0.0 0.5 0.0 0.8 0.5 3.8 4.0 4.0 3.7 3.4 4.1 4.9 4.7 3.7 3.5 4.7 2.7 0.1 12.8 3.7 2.3 0.4 0.3 2.3 8.1 0.0 0.2 17.7 9.9 0.6 24.3 10.8 7.3 0.0 0.0 0.1 1.4 5.9 16.1 1.4 17.1 0.4 0.2 0.0 2.7 0.0 13.8 0.1 1.3 23.4 5.2 0.0 0.2 0.4 0.0 0.1 0.0 0.0 2.0 16.2 0.0 0.5 0.6 0.3 0.3 0.0 0.0 0.0 20.4 0.0 0.0 0.1 11.8 1.4 0.0 0.4 2.4 2.9 0.0 39.8 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.1 2.5 5.0 TMPRSS5 "MGC141886, MGC148044" ENSG00000166682 "Transmembrane serine protease 5" Q9H3S3 11 113687547-113706373 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.6;choroid plexus: 20.8" "Cell type enhanced" "Detected in some" "Astrocytes: 26.4;Excitatory neurons: 5.4;Horizontal cells: 5.0;Oligodendrocytes: 15.5" "Cancer enhanced" "Detected in some" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.0;CAPAN-2: 3.2;OE19: 2.0;WM-115: 2.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010992 Approved Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA010992: AB_1858152" "unprognostic (1.53e-2)" "unprognostic (3.81e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (2.99e-3)" "unprognostic (3.08e-1)" "unprognostic (5.19e-3)" "unprognostic (8.49e-2)" "unprognostic (8.13e-2)" "unprognostic (3.38e-2)" "unprognostic (1.96e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (4.04e-3)" 1.3 0.5 28.1 0.2 34.7 1.4 2.0 24.9 39.0 0.8 20.8 0.7 0.1 0.5 0.2 0.5 0.7 0.7 1.0 28.2 27.0 1.0 1.0 0.7 0.2 34.0 29.8 0.6 0.5 0.0 1.6 0.2 33.1 0.8 0.3 1.1 9.6 0.3 2.6 2.1 0.7 0.3 28.5 0.8 0.8 2.1 32.1 0.3 0.6 0.5 0.3 0.7 1.0 50.6 0.2 0.3 2.0 1.1 0.2 0.1 0.3 0.5 0.2 0.3 0.4 1.1 3.2 0.1 1.4 0.2 0.3 0.4 0.1 0.2 0.1 0.2 0.6 0.4 0.3 0.0 0.1 0.5 0.4 0.2 0.2 0.2 0.5 0.2 0.3 0.7 0.4 0.2 0.4 0.0 0.4 0.6 0.2 2.0 0.1 0.4 0.2 0.0 0.3 0.2 0.3 0.4 0.2 0.0 1.6 0.2 0.2 0.2 0.2 0.4 0.7 0.3 0.3 0.2 0.1 0.0 0.1 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 34.7 24.9 39.0 28.2 27.0 34.0 29.8 33.1 28.5 32.1 50.6 0.2 0.0 0.0 26.4 0.2 0.3 0.2 0.0 0.0 0.5 1.0 0.9 0.5 0.0 0.1 1.8 2.1 0.0 0.2 0.2 0.0 0.3 0.1 0.3 0.2 0.3 0.0 1.3 5.4 0.9 0.0 0.3 0.0 0.4 0.0 0.4 0.4 0.2 0.1 5.0 2.8 0.0 0.0 0.0 0.3 0.3 0.3 0.1 0.0 2.8 0.1 3.2 0.0 3.5 15.5 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.1 1.3 0.0 0.5 0.1 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 TMTC1 "ARG99, FLJ31400, FLJ41625, OLF" ENSG00000133687 "Transmembrane O-mannosyltransferase targeting cadherins 1" Q8IUR5 12 29500840-29784759 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Astrocytes: 64.6;Excitatory neurons: 186.0;Inhibitory neurons: 200.5;Skeletal myocytes: 60.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 83.0;HSkMC: 56.9;hTERT-HME1: 103.8;LHCN-M2: 58.8;RH-30: 122.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016720 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA016720: AB_1858155" "unprognostic (1.67e-1)" "unprognostic (6.35e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.63e-3)" "unprognostic (4.53e-2)" "unprognostic (3.88e-2)" "unprognostic (8.36e-2)" "unprognostic (1.77e-1)" "unprognostic (8.90e-3)" "unprognostic (3.08e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.49e-4)" "unprognostic (5.89e-3)" "unprognostic (6.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.51e-3)" 36.7 14.1 14.5 5.2 21.0 0.2 16.8 6.7 13.5 11.9 13.3 11.9 3.1 9.0 3.0 6.8 14.3 7.1 16.5 20.0 25.0 14.7 2.4 8.7 2.7 11.4 24.0 9.3 2.6 28.0 10.7 2.8 15.8 6.9 5.9 2.6 4.5 8.8 18.5 4.0 6.4 13.2 7.9 42.4 8.3 2.4 25.1 6.9 4.7 31.2 2.1 12.1 8.2 6.3 0.0 0.0 15.3 0.0 47.7 31.6 0.1 14.7 33.1 4.3 3.4 0.0 0.2 0.1 7.4 10.0 17.6 0.0 0.5 0.2 0.2 0.3 4.6 0.0 41.5 0.7 83.0 2.1 0.0 56.9 5.6 40.3 103.8 12.2 2.2 0.0 0.0 2.2 58.8 0.0 0.0 0.0 11.1 0.2 20.8 0.0 122.4 2.1 0.0 0.3 1.2 1.2 1.7 0.0 4.1 5.4 0.0 0.8 6.2 3.7 2.4 2.3 12.5 19.6 0.0 0.0 27.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 14.5 21.0 6.7 13.5 20.0 25.0 11.4 24.0 15.8 7.9 25.1 6.3 105.0 3.2 0.6 64.6 0.9 3.3 1.0 6.1 11.4 12.1 1.3 10.4 32.3 0.0 2.4 3.7 0.0 0.1 0.0 0.0 0.0 0.1 29.6 7.7 16.2 57.9 0.0 0.0 186.0 0.0 0.0 17.5 2.0 7.0 0.0 4.3 54.7 5.4 0.5 0.0 200.5 0.2 0.0 17.7 4.2 7.5 8.1 4.9 10.6 30.9 0.5 0.5 0.0 9.5 5.7 0.0 0.0 18.4 0.3 4.0 0.1 0.7 6.0 1.3 46.0 60.3 24.9 2.4 1.7 1.3 2.0 1.9 1.0 21.9 0.0 0.4 TMTC3 "FLJ90492, SMILE" ENSG00000139324 "Transmembrane O-mannosyltransferase targeting cadherins 3" Q6ZXV5 12 88142296-88199887 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transferase "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038550 Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038550: AB_10672715" "unprognostic (1.05e-1)" "unprognostic (6.16e-2)" "unprognostic (1.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (5.28e-2)" "unprognostic (3.62e-3)" "unprognostic (1.71e-2)" "unprognostic (1.46e-1)" "unprognostic (4.44e-1)" "unprognostic (8.07e-3)" "unprognostic (2.56e-2)" "unprognostic (2.28e-1)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" 5.9 4.4 3.6 3.8 3.8 1.7 6.7 5.8 4.7 5.6 2.1 4.5 5.4 6.4 5.2 9.1 3.9 5.7 3.8 3.9 4.6 8.1 9.0 5.2 2.9 3.4 3.9 5.3 3.2 6.2 2.8 10.2 4.1 7.4 4.7 7.9 3.8 6.3 1.7 12.5 4.4 9.2 3.2 3.9 3.8 4.1 3.6 4.0 6.3 4.3 4.5 6.8 4.7 4.1 13.2 14.0 12.6 11.9 28.8 25.4 22.5 28.1 26.6 15.8 16.9 20.3 9.2 4.1 5.0 25.8 9.6 28.9 13.5 22.4 26.5 2.4 10.2 4.0 9.5 9.3 15.0 4.3 2.5 21.7 12.0 30.5 12.0 16.2 24.9 3.4 8.9 1.4 17.8 7.9 3.0 5.5 9.7 5.0 7.3 2.6 27.4 4.1 13.7 21.3 10.7 10.6 22.8 16.1 7.3 13.3 25.9 4.3 26.4 21.8 12.0 19.4 13.7 4.5 6.3 4.7 6.8 5.0 16.5 7.4 1.3 2.3 1.8 1.1 2.2 2.3 2.0 1.4 0.9 1.8 2.4 2.0 1.3 1.2 1.6 0.9 1.7 0.7 3.6 3.8 5.8 4.7 3.9 4.6 3.4 3.9 4.1 3.2 3.6 4.1 15.9 12.8 8.2 19.6 6.9 34.2 24.4 29.1 24.5 12.5 11.4 8.1 11.1 5.7 20.0 7.3 27.1 29.6 3.5 6.7 3.9 14.5 26.8 23.7 22.2 16.9 3.6 9.5 51.6 10.8 18.2 23.8 8.6 21.9 9.5 12.4 15.7 19.2 8.2 13.5 46.8 5.9 75.3 5.9 6.0 18.2 20.2 3.7 8.8 20.6 2.8 8.3 2.1 28.1 42.4 12.4 4.9 19.5 4.6 18.0 7.3 13.9 34.9 23.4 19.7 17.1 22.3 12.0 8.7 32.6 40.5 17.8 5.2 14.1 7.1 14.4 TNFAIP8L3 FLJ41287 ENSG00000183578 "TNF alpha induced protein 8 like 3" Q5GJ75 15 51056598-51105276 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 86.9;smooth muscle: 84.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 10.3;Inhibitory neurons: 14.4;Langerhans cells: 10.8;Smooth muscle cells: 9.3;Spermatocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;ASC TERT1: 87.8;HUVEC TERT2: 78.7;LHCN-M2: 74.5;TIME: 105.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077484 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA077484: AB_2732347" "unprognostic (1.38e-1)" "unprognostic (6.22e-2)" "unprognostic (1.12e-3)" "unprognostic (6.63e-2)" "unprognostic (2.54e-1)" "unprognostic (1.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-2)" "unprognostic (4.21e-2)" "unprognostic (4.70e-3)" "unprognostic (6.54e-2)" "unprognostic (9.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (3.51e-4)" 9.4 3.8 9.2 7.1 8.3 0.8 5.7 3.5 8.2 13.7 4.3 8.6 1.6 86.9 6.0 20.4 45.6 6.2 6.3 15.3 6.6 2.7 2.4 15.5 3.9 5.5 8.5 15.9 2.4 0.8 3.0 2.0 4.8 6.8 8.6 0.3 3.9 5.4 4.7 23.1 7.9 84.8 4.3 19.9 5.8 4.4 6.6 0.9 5.4 3.5 3.2 18.6 15.1 5.6 0.1 0.4 0.1 0.2 35.0 87.8 0.4 0.3 0.1 1.0 1.6 0.1 1.0 0.1 1.5 5.0 11.2 0.1 1.2 0.8 0.4 0.1 0.7 0.0 2.4 5.9 9.1 0.3 1.9 32.5 7.1 6.7 26.8 5.8 78.7 0.1 0.1 0.1 74.5 0.9 0.0 0.6 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.1 0.1 0.1 0.9 0.5 0.6 105.5 8.0 0.5 26.5 2.3 0.4 0.0 0.1 16.7 0.1 0.1 0.9 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.6 0.3 0.2 0.2 0.0 0.0 9.2 8.3 3.5 8.2 15.3 6.6 5.5 8.5 4.8 4.3 6.6 5.6 1.2 0.0 0.5 4.6 0.0 3.3 1.1 0.4 0.0 0.1 0.2 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.3 2.3 1.7 3.9 10.3 0.0 4.5 0.4 0.0 5.8 0.0 0.1 0.0 7.1 1.8 0.3 2.9 0.0 14.4 3.3 2.0 2.9 10.8 0.7 9.0 3.5 1.8 1.0 0.6 0.1 0.0 1.0 2.6 0.1 1.5 5.3 0.1 0.4 0.0 0.1 1.3 0.2 6.6 1.6 9.3 23.7 0.8 0.3 8.4 0.0 0.1 0.1 1.5 0.5 TNFRSF18 "AITR, CD357, GITR" ENSG00000186891 "TNF receptor superfamily member 18" Q9Y5U5 1 1203508-1206592 "CD markers, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 189.0;dendritic cells: 72.2;Langerhans cells: 86.4;Melanocytes: 49.8;Plasma cells: 55.3;Suprabasal keratinocytes: 150.6;T-cells: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cell: 184.5;T-reg: 71.8" "Group enriched" "Detected in many" 11 "NK-cells: 184.5;T-cells: 71.8" "Group enriched" "Detected in some" 12 "RPMI-8226: 225.6;SCLC-21H: 152.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008025 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA008025: AB_1849696" "unprognostic (1.20e-3)" "unprognostic (4.61e-2)" "unprognostic (4.59e-2)" "prognostic favorable (7.72e-6)" "unprognostic (2.73e-4)" "prognostic favorable (4.12e-4)" "unprognostic (3.43e-2)" "unprognostic (2.31e-1)" "unprognostic (3.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.00e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.40e-11)" "unprognostic (1.02e-3)" "unprognostic (2.39e-1)" "unprognostic (3.74e-1)" "unprognostic (2.08e-1)" 1.9 0.6 1.1 7.3 1.3 2.9 2.4 2.5 3.1 11.1 0.7 6.0 7.2 1.4 0.0 6.3 1.4 0.9 0.5 1.0 0.6 2.8 0.9 4.6 5.5 1.3 0.6 0.3 0.3 9.4 4.9 0.3 1.3 2.8 1.5 0.0 5.6 0.6 0.8 38.5 7.1 0.3 0.6 9.0 5.2 0.9 0.9 1.9 1.4 0.0 3.8 2.0 3.3 1.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.3 1.2 0.1 0.5 16.1 0.1 0.1 225.6 0.3 0.0 152.8 0.2 0.0 0.6 0.0 0.0 8.2 0.1 0.0 0.0 0.3 0.2 0.0 0.9 0.3 0.2 0.6 0.1 0.0 0.2 0.2 0.0 6.8 0.1 12.6 4.6 28.9 4.4 0.1 11.5 0.9 1.5 0.8 184.5 0.1 0.3 71.8 6.7 1.1 1.3 2.5 3.1 1.0 0.6 1.3 0.6 1.3 0.6 0.9 1.2 11.2 0.0 1.3 0.3 23.5 189.0 12.5 15.5 16.5 0.0 5.0 3.0 2.9 0.0 3.2 0.0 0.0 0.0 72.2 0.3 0.0 0.8 0.0 1.2 1.2 4.1 3.5 0.0 2.0 0.6 1.3 4.7 1.1 2.9 45.7 0.0 0.7 0.0 0.8 0.0 0.3 0.2 20.3 0.3 86.4 0.0 0.0 5.4 49.8 0.0 12.7 0.0 21.6 0.5 0.3 0.4 0.0 0.0 55.3 10.1 0.1 0.1 0.8 0.0 0.0 6.2 2.2 0.0 0.0 0.3 150.6 0.0 75.7 0.0 0.8 7.0 TNKS1BP1 "FLJ45975, KIAA1741, TAB182" ENSG00000149115 "Tankyrase 1 binding protein 1" Q9C0C2 11 57299638-57324952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037929, HPA037930" Enhanced Uncertain "Plasma membrane" NA NA 180000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA037929: AB_10672613, HPA037930: AB_2675745" "unprognostic (7.31e-2)" "unprognostic (1.66e-2)" "unprognostic (5.38e-2)" "unprognostic (2.25e-1)" "unprognostic (3.13e-1)" "unprognostic (9.17e-2)" "unprognostic (2.47e-2)" "unprognostic (7.90e-2)" "unprognostic (4.27e-1)" "unprognostic (2.67e-2)" "unprognostic (4.22e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (2.11e-8)" "unprognostic (2.46e-1)" "unprognostic (2.31e-2)" "unprognostic (2.41e-1)" "unprognostic (3.07e-1)" 62.7 27.3 11.8 17.3 10.2 3.3 41.9 4.6 9.4 43.3 18.0 23.6 28.8 40.3 30.3 55.4 35.3 28.1 23.3 11.3 9.2 14.7 31.6 40.3 6.6 9.6 8.8 32.2 30.9 18.9 17.1 29.5 7.2 33.6 16.2 3.3 44.2 40.2 67.2 83.0 26.6 29.4 4.9 18.1 52.8 10.1 11.0 22.3 25.0 29.9 14.3 38.5 45.6 6.7 89.5 58.7 41.2 33.6 127.8 97.1 31.0 61.5 113.8 46.3 42.5 26.1 59.5 2.0 38.5 101.2 49.6 151.7 31.4 105.3 30.1 34.2 10.4 11.5 38.2 12.2 86.6 14.4 4.3 96.8 123.5 70.9 54.6 57.5 60.0 12.4 13.2 9.3 65.3 45.4 11.0 14.7 45.8 46.5 45.9 16.9 57.2 25.9 53.5 116.6 14.6 22.6 81.5 121.5 44.3 29.0 182.2 11.9 115.1 47.3 45.8 56.6 35.2 15.0 4.1 11.3 107.0 4.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.8 10.2 4.6 9.4 11.3 9.2 9.6 8.8 7.2 4.9 11.0 6.7 38.1 12.8 35.4 12.7 1.9 83.6 28.0 61.9 40.9 4.8 24.8 23.9 7.9 38.6 39.0 44.1 2.1 16.8 1.3 27.3 0.0 31.8 1.8 18.5 25.4 25.9 18.0 7.4 7.2 22.3 3.2 31.2 49.5 38.4 2.5 3.7 19.6 46.0 3.9 8.4 4.8 25.8 18.3 1.5 25.4 2.9 48.1 3.8 17.8 1.9 0.7 4.0 0.0 4.5 2.4 38.8 14.3 49.2 0.6 41.2 18.2 2.4 15.4 1.3 32.9 41.2 26.9 1.5 3.0 68.9 88.2 24.5 2.3 23.4 14.5 36.8 TNN TNW ENSG00000120332 "Tenascin N" Q9UQP3 1 175067833-175148075 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 12.0;breast: 4.9" "Cell type enhanced" "Detected in some" "Adipocytes: 6.1;Fibroblasts: 7.5;Hepatic stellate cells: 2.5;Langerhans cells: 2.5;Smooth muscle cells: 10.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.6;NB-4: 3.6;THP-1: 11.1;U-266/70: 2.7;U-937: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB010907, HPA026726, HPA026764" Uncertain "Secreted to extracellular matrix" NA NA 34000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010907: AB_477565, HPA026726: AB_10601771, HPA026764: AB_10601859" "unprognostic (1.16e-3)" "unprognostic (2.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-2)" "unprognostic (1.34e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (3.55e-1)" "unprognostic (5.25e-3)" "unprognostic (1.01e-2)" "unprognostic (4.69e-1)" "unprognostic (5.07e-1)" "unprognostic (1.08e-3)" "unprognostic (1.76e-2)" "unprognostic (9.38e-3)" "unprognostic (1.89e-2)" "unprognostic (1.02e-2)" 12.0 0.2 0.0 0.1 0.1 0.0 4.9 0.0 0.1 0.1 0.1 0.3 0.8 0.0 0.0 0.1 0.0 1.7 0.3 0.2 0.0 0.4 1.3 0.4 0.1 0.0 0.1 0.0 0.3 0.8 2.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 3.1 0.4 0.4 0.1 0.4 0.4 0.1 0.1 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 11.1 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 6.1 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.7 0.0 0.1 7.5 0.0 0.1 0.0 0.0 2.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 10.4 0.4 1.4 0.0 1.8 0.1 0.1 0.0 0.0 0.1 TNNT1 "ANM, FLJ98147, MGC104241, NEM5, STNT, TNT, TNTS" ENSG00000105048 "Troponin T1, slow skeletal type" P13805 19 55132698-55149206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 29 "skeletal muscle: 21567.3;tongue: 13372.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 61.2;Basal squamous epithelial cells: 47.8;Cardiomyocytes: 51.5;Skeletal myocytes: 192.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "eosinophil: 211.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 211.5" "Cell line enhanced" "Detected in many" "HMC-1: 829.4;RH-30: 638.8" "Region enriched" "Detected in many" 5 "thalamus: 125.0" "Region enhanced" "Detected in all" "thalamus: 23.1" "CAB015168, HPA058448" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 79000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Golgi apparatus, Cytosol" "CAB015168: AB_2206426, HPA058448: AB_2683720" "unprognostic (1.88e-1)" "unprognostic (7.23e-2)" "prognostic unfavorable (4.66e-4)" "prognostic unfavorable (4.66e-4)" "unprognostic (3.47e-3)" "unprognostic (3.92e-3)" "unprognostic (1.35e-3)" "unprognostic (1.03e-3)" "unprognostic (2.46e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.53e-4)" "unprognostic (3.23e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.91e-2)" "unprognostic (4.01e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-2)" 5.7 1.2 42.1 0.4 45.7 3.3 5.0 44.3 55.4 1.9 36.4 2.7 1.0 1.1 1.0 593.5 8.4 1.0 256.7 43.9 38.9 1.3 2.5 8.3 0.4 36.7 41.4 1.5 2.5 2.3 8.5 6.0 38.5 200.4 0.6 0.6 171.2 0.4 21567.3 48.5 2.0 0.4 35.6 1.9 1.9 10.6 40.8 3.4 3.8 13372.6 2.0 1.7 5.8 40.8 178.4 102.3 1.0 22.4 0.0 1.7 33.3 8.0 30.1 11.1 32.7 37.9 115.8 2.6 66.5 3.2 88.8 88.5 24.0 76.0 9.4 11.8 192.2 33.6 11.8 6.7 3.7 2.7 829.4 36.6 121.3 3.4 127.0 125.7 0.5 35.1 171.7 158.6 10.3 168.0 3.4 0.3 21.4 45.0 202.1 113.9 638.8 21.2 26.5 5.8 6.6 49.3 10.7 1.3 57.9 8.5 106.3 102.7 2.9 163.6 238.9 6.5 12.4 1.2 7.0 8.8 171.8 26.4 50.9 2.4 39.4 211.5 0.3 21.7 0.3 0.2 0.3 0.3 37.4 0.4 0.3 0.4 1.9 0.6 10.2 0.9 0.1 12.2 42.1 45.7 44.3 55.4 43.9 38.9 36.7 41.4 38.5 35.6 40.8 40.8 0.0 0.0 0.0 0.7 0.3 61.2 0.6 25.1 47.8 4.5 0.5 5.3 51.5 0.0 2.8 0.0 0.0 2.2 0.0 0.5 0.0 2.1 2.1 9.7 0.3 2.6 2.4 2.7 0.4 0.0 18.0 18.8 0.0 3.4 0.0 22.1 1.4 0.0 12.9 0.0 0.7 0.3 0.0 13.2 3.8 10.7 0.3 8.9 3.6 0.0 25.8 0.7 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.7 0.0 192.0 3.5 4.3 34.1 2.5 30.4 3.6 1.6 1.2 0.8 0.2 TNXB "TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 274.8" "Cell type enhanced" "Detected in many" "Adipocytes: 54.7;Fibroblasts: 318.4;Granulosa cells: 94.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 12.4;ASC TERT1: 20.1;U-2197: 15.8;U-87 MG: 8.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" 68.0 274.8 2.0 0.9 3.1 3.4 40.0 4.4 1.8 45.1 3.5 35.9 3.0 66.7 3.2 18.1 37.4 4.7 73.8 0.7 0.8 13.0 17.6 51.1 0.8 1.5 1.1 67.0 3.7 0.4 6.8 3.8 1.5 15.6 1.7 0.3 19.5 1.0 14.2 27.4 29.0 3.1 2.2 30.7 18.8 11.4 3.0 0.7 27.7 7.2 0.4 34.5 35.2 0.4 0.1 0.3 0.3 0.2 12.4 20.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.4 1.2 0.0 0.1 0.0 0.0 0.1 1.3 1.1 0.2 0.6 0.0 2.8 0.0 0.3 0.2 0.2 0.5 0.0 0.5 0.0 0.5 0.7 0.4 0.0 0.2 0.0 0.1 0.3 0.0 3.5 0.3 0.1 0.2 0.0 0.1 0.1 0.2 1.3 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.4 15.8 0.0 0.4 0.4 0.2 8.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 3.1 4.4 1.8 0.7 0.8 1.5 1.1 1.5 2.2 3.0 0.4 54.7 3.2 2.4 2.6 0.5 32.9 0.2 0.3 0.6 1.3 1.3 1.8 2.5 4.3 0.2 0.0 0.0 0.5 1.0 0.0 0.0 0.2 3.0 1.3 39.7 38.8 0.0 25.0 7.1 0.0 2.6 318.4 6.1 1.1 0.0 94.8 12.8 0.9 0.7 0.0 4.2 0.1 0.0 0.6 39.1 2.8 27.1 4.7 32.0 17.8 0.0 1.2 0.0 1.0 1.2 0.0 0.1 4.5 2.5 0.5 0.0 0.3 0.9 0.6 0.0 21.7 20.8 4.1 2.1 1.6 26.6 1.0 4.8 5.6 0.2 0.4 TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347992 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 213.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 170.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000818, HPA001749" Approved Approved "Plasma membrane,Centriolar satellite,Cytosol" NA NA 44000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane, Centriolar satellite" "HPA000818: AB_2666101, HPA001749: AB_1080323" "unprognostic (3.75e-1)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.11e-2)" "unprognostic (7.55e-2)" "unprognostic (4.07e-3)" "unprognostic (2.24e-1)" "unprognostic (9.92e-2)" "unprognostic (2.32e-1)" "unprognostic (3.71e-1)" "unprognostic (8.16e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" "unprognostic (7.54e-3)" "unprognostic (3.31e-2)" 34.7 47.8 20.8 17.0 19.4 60.8 32.1 19.9 25.8 43.6 23.6 22.7 29.1 26.6 12.7 76.5 26.8 24.9 43.2 19.8 26.6 32.7 49.0 37.1 15.3 30.2 24.5 21.5 20.2 48.5 37.4 27.7 32.9 23.2 9.8 5.9 60.6 11.7 213.8 74.9 28.4 10.8 19.6 23.9 20.8 25.9 24.8 13.1 26.5 68.6 12.7 19.5 45.0 22.1 15.8 15.3 8.8 14.3 58.3 34.9 42.3 15.5 43.8 28.4 31.1 21.5 14.3 6.2 28.0 45.4 18.3 7.3 8.6 15.6 9.9 18.7 21.3 5.3 17.1 43.8 58.6 10.8 23.6 49.8 19.2 39.6 13.3 18.5 19.8 11.6 10.3 15.3 14.1 13.8 8.2 27.5 7.0 18.9 8.6 14.9 12.3 13.2 10.9 11.3 14.9 12.1 34.1 34.8 34.5 7.3 18.0 16.7 22.0 34.0 29.4 27.3 7.7 18.0 12.4 16.7 45.7 10.5 11.4 18.6 100.9 44.5 19.3 60.7 15.6 13.6 29.5 18.4 48.0 11.0 22.6 15.7 129.1 15.1 66.2 25.9 48.2 63.3 20.8 19.4 19.9 25.8 19.8 26.6 30.2 24.5 32.9 19.6 24.8 22.1 10.1 22.4 36.9 8.8 12.7 12.7 10.3 29.5 7.4 11.1 19.1 11.0 23.2 15.7 33.0 12.9 12.5 64.6 13.8 41.6 27.4 40.9 29.9 32.0 17.8 14.2 16.2 9.7 9.3 38.9 57.1 22.6 15.3 48.0 22.8 10.4 16.1 34.0 60.8 11.8 15.2 18.1 50.8 33.5 35.2 21.4 11.5 45.2 19.6 7.5 34.0 19.5 9.2 6.6 13.2 34.2 21.5 12.8 5.7 11.9 55.3 34.9 24.2 8.2 6.6 16.6 15.4 23.5 5.6 17.3 21.9 170.2 18.2 13.4 15.2 10.7 TONSL "IKBR, NFKBIL2" ENSG00000160949 "Tonsoku like, DNA repair protein" Q96HA7 8 144428775-144444440 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 76.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024679, HPA046494" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear bodies" "HPA024679: AB_1854441, HPA046494: AB_2679673" "unprognostic (6.68e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.88e-2)" "unprognostic (7.35e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.04e-3)" "unprognostic (7.81e-2)" "unprognostic (4.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.62e-7)" "unprognostic (3.24e-2)" "unprognostic (1.78e-1)" "unprognostic (9.11e-3)" "unprognostic (7.96e-2)" 1.0 2.1 0.4 2.5 0.4 8.5 1.3 0.4 1.3 1.7 0.0 3.4 3.5 1.6 0.2 3.9 1.4 0.6 1.4 0.3 0.3 1.4 1.7 1.3 2.3 1.3 0.6 1.7 1.5 0.4 0.9 1.5 1.1 1.6 0.8 0.1 1.5 0.8 0.5 3.3 4.4 0.6 0.1 3.9 2.2 3.8 0.8 2.3 2.4 0.1 1.4 2.3 2.1 0.3 21.2 18.6 13.7 21.7 1.0 1.7 33.0 17.6 3.4 10.4 8.1 15.0 17.9 19.6 17.5 2.7 4.9 14.2 13.4 10.7 2.3 20.2 26.6 46.5 26.1 15.9 0.6 14.3 28.1 1.7 1.5 10.9 2.1 2.6 5.0 26.5 53.0 14.3 4.2 43.4 35.5 24.5 19.4 20.4 26.7 42.6 8.9 20.3 5.9 22.6 22.9 13.0 18.4 12.3 7.8 5.2 17.6 13.2 5.9 12.7 52.3 14.5 21.7 5.0 9.9 12.0 12.3 30.2 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.4 1.3 0.3 0.3 1.3 0.6 1.1 0.1 0.8 0.3 2.5 6.4 22.4 1.6 2.9 8.9 5.2 1.0 1.2 3.1 3.5 2.9 2.3 8.6 3.7 1.8 2.1 4.1 1.3 20.2 0.0 0.9 0.4 4.3 2.7 4.3 2.4 7.2 2.4 1.0 5.3 3.8 11.7 6.1 2.5 8.5 2.9 11.4 4.5 1.7 1.0 14.6 0.0 0.9 16.7 0.7 0.3 3.0 14.2 1.9 1.2 1.1 1.0 0.5 0.8 1.2 7.1 1.2 4.0 3.9 76.5 7.7 4.1 3.0 6.6 6.4 2.8 4.6 7.8 3.4 11.2 1.2 3.1 3.3 15.9 3.9 TOX3 "CAGF9, TNRC9" ENSG00000103460 "TOX high mobility group box family member 3" O15405 16 52436417-52547802 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.9;retina: 17.6;stomach 1: 20.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 52.9;Enteroendocrine cells: 61.7;Inhibitory neurons: 138.9;Muller glia cells: 162.1;Oligodendrocyte precursor cells: 51.8;Oligodendrocytes: 75.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 46.1;HAP1: 22.1;Hep G2: 20.8;OE19: 25.8;RT4: 97.1;SCLC-21H: 30.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040240, HPA040376" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm Cytosol "HPA040240: , HPA040376: AB_10795522" "unprognostic (1.14e-2)" "unprognostic (9.75e-3)" "unprognostic (9.08e-3)" "unprognostic (3.32e-2)" "unprognostic (3.50e-1)" "unprognostic (2.31e-1)" "unprognostic (4.74e-3)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.94e-2)" "unprognostic (2.59e-1)" "unprognostic (4.60e-3)" "prognostic favorable (3.08e-12)" "unprognostic (1.19e-1)" "unprognostic (1.31e-1)" "prognostic favorable (3.95e-4)" 0.4 3.0 4.7 1.4 5.6 0.0 3.8 1.2 6.0 7.6 0.3 15.6 9.3 1.3 4.4 0.6 3.1 6.9 0.0 5.3 4.4 9.5 5.2 1.4 0.1 4.6 3.5 0.9 2.6 0.0 2.3 0.2 3.0 1.8 17.9 17.6 8.9 0.5 4.0 0.7 9.3 1.0 5.1 0.0 20.3 0.6 8.4 1.3 0.0 0.5 0.2 5.7 1.0 6.8 0.0 5.8 46.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 3.5 0.0 0.3 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 25.8 0.0 0.0 8.0 0.2 10.7 97.1 30.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 5.6 1.2 6.0 5.3 4.4 4.6 3.5 3.0 5.1 8.4 6.8 0.2 6.4 8.2 1.3 0.0 1.0 0.5 2.8 0.6 4.1 20.0 12.6 0.7 52.9 7.7 35.0 0.0 0.0 0.0 47.6 3.9 1.6 3.2 1.6 0.4 0.3 61.7 0.0 3.9 5.1 0.0 1.5 29.6 6.1 0.0 0.1 0.7 4.6 0.1 40.4 138.9 31.7 2.0 0.0 0.3 1.8 0.6 0.2 0.0 8.4 0.0 162.1 0.0 51.8 75.0 15.3 15.2 0.0 0.2 11.8 16.6 14.0 12.3 3.8 0.0 3.3 0.8 0.1 0.8 0.3 0.3 0.0 0.4 9.7 32.6 6.5 TPD52 "D52, hD52, N8L" ENSG00000076554 "Tumor protein D52" P55327 8 80034745-80231232 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 187.6" "Cell type enhanced" "Detected in many" "Ionocytes: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 50.5" "Group enriched" "Detected in many" 5 "B-cells: 50.5;NK-cells: 15.1;T-cells: 22.0" "Cell line enhanced" "Detected in many" "Karpas-707: 252.6;SK-BR-3: 572.5" "HPA028427, HPA062167" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 310000 "Cluster 43: B-cells - Humoral immune response" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "Golgi apparatus" "HPA028427: AB_10610561, HPA062167: AB_2684704" "prognostic unfavorable (1.11e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-2)" "unprognostic (3.77e-3)" "unprognostic (8.24e-2)" "unprognostic (3.75e-1)" "unprognostic (7.99e-3)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.77e-6)" "unprognostic (2.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (1.70e-2)" 5.4 9.2 34.9 28.4 40.2 8.9 75.9 34.2 69.4 19.6 36.6 117.7 98.9 9.9 56.2 34.9 15.3 31.1 11.7 42.9 35.4 46.5 30.7 19.8 44.0 33.2 37.1 2.4 41.8 27.4 34.3 22.9 36.3 104.8 129.7 187.6 80.7 18.3 8.6 46.9 100.3 10.4 32.8 16.0 84.1 5.2 53.3 15.5 64.5 9.8 56.2 20.9 20.2 48.1 131.8 34.9 1.6 23.0 0.0 0.0 51.7 8.6 12.9 34.7 17.1 18.0 37.4 189.9 45.2 0.8 25.5 52.5 52.7 36.3 24.6 23.8 44.2 26.8 46.9 29.4 0.2 8.6 0.7 0.0 25.2 0.1 12.2 21.6 2.0 128.9 0.4 252.6 0.1 43.6 42.6 39.4 11.7 148.8 86.0 0.3 0.7 122.0 60.7 31.6 64.9 44.1 40.1 572.5 110.7 51.0 55.9 34.2 2.1 0.0 35.2 0.6 30.8 94.1 87.1 155.2 22.5 0.2 2.6 0.6 0.1 5.5 12.7 0.1 22.0 50.5 12.4 11.1 2.5 44.7 8.1 9.3 0.5 15.1 0.1 5.2 9.1 8.3 34.9 40.2 34.2 69.4 42.9 35.4 33.2 37.1 36.3 32.8 53.3 48.1 17.3 44.8 67.8 10.4 133.6 80.7 89.6 83.4 51.2 171.1 105.6 54.2 22.2 82.9 78.1 66.2 118.9 98.9 28.6 230.9 170.2 112.8 20.6 25.2 8.4 26.2 169.9 11.6 85.4 79.6 116.9 6.7 97.3 72.8 1.3 15.3 25.7 40.6 13.1 32.0 53.9 331.9 476.0 14.6 24.2 13.0 1.2 10.8 104.9 37.5 91.2 50.3 60.8 69.9 181.0 79.7 317.5 1.5 270.5 214.4 132.3 135.3 21.4 232.2 0.0 49.6 8.3 1.6 18.2 91.4 124.6 231.2 51.3 0.3 247.1 135.4 TPD52L1 "D53, hD53, TPD53" ENSG00000111907 "TPD52 like 1" Q16890 6 125119049-125264407 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.3;salivary gland: 298.3" "Cell type enhanced" "Detected in many" "Astrocytes: 390.1;Squamous epithelial cells: 272.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 269.1;hTCEpi: 234.3;MCF7: 365.5;RPTEC TERT1: 271.4;SK-BR-3: 189.4;T-47d: 162.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027915, HPA027916" Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions, Cytosol" "HPA027915: AB_10602074, HPA027916: AB_10601860" "unprognostic (1.44e-1)" "unprognostic (2.01e-2)" "unprognostic (2.76e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (2.87e-2)" "unprognostic (1.38e-2)" "unprognostic (2.14e-1)" "unprognostic (7.85e-2)" "unprognostic (7.80e-2)" "unprognostic (9.42e-3)" "unprognostic (1.76e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.06e-1)" "unprognostic (6.83e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (5.34e-4)" 44.7 258.3 83.9 10.1 96.2 0.8 67.0 72.6 97.4 35.8 103.4 36.2 9.7 15.2 68.8 152.4 34.6 27.3 71.4 78.4 81.3 40.6 58.4 10.9 6.6 81.4 76.8 20.7 47.1 67.3 24.8 8.9 78.8 41.0 13.0 1.9 298.3 79.1 111.9 47.9 10.6 12.3 68.5 2.0 43.1 5.1 81.5 3.4 60.7 126.2 12.3 59.6 60.8 76.6 37.7 42.0 0.5 269.1 2.4 0.6 63.3 6.2 5.9 0.0 0.7 67.3 46.9 0.1 136.2 31.2 9.1 83.8 8.4 58.2 0.2 0.8 58.0 0.8 58.0 0.5 5.7 0.2 0.1 7.4 234.3 0.1 30.7 82.5 0.0 0.0 30.5 0.6 4.7 365.5 0.0 0.7 4.4 36.8 22.7 0.4 0.1 0.0 271.4 9.8 9.1 0.2 70.5 189.4 4.6 9.6 162.3 0.8 0.2 1.8 5.9 0.5 2.0 0.1 0.1 0.2 1.0 0.3 0.7 1.8 0.5 0.3 0.3 0.2 0.3 0.3 0.6 0.2 0.2 0.4 0.7 0.5 2.7 2.6 0.1 0.4 0.2 0.4 83.9 96.2 72.6 97.4 78.4 81.3 81.4 76.8 78.8 68.5 81.5 76.6 141.6 0.0 28.3 390.1 2.2 19.6 44.6 70.2 128.1 3.8 164.4 154.9 45.8 25.8 51.7 125.0 4.2 32.7 3.2 3.9 176.1 30.7 6.9 71.7 21.1 87.2 16.2 0.0 16.4 110.8 140.2 18.8 13.7 184.5 2.5 29.5 15.4 59.9 10.9 0.0 48.2 11.3 83.4 2.1 5.2 4.9 17.4 3.4 131.6 28.1 0.6 3.9 1.0 11.6 2.9 35.3 2.3 36.5 2.6 37.1 10.9 45.4 15.7 1.3 0.0 177.1 10.1 5.7 9.2 272.2 37.2 14.4 3.5 53.8 17.8 19.2 TPM2 "AMCD1, DA1, NEM4" ENSG00000198467 "Tropomyosin 2" P07951 9 35681992-35690056 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 39012.3;tongue: 16773.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1066.2;Peritubular cells: 2072.1;Sertoli cells: 2222.0;Smooth muscle cells: 2341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 812 "plasmacytoid DC: 398.6" "Lineage enriched" "Detected in single" 920 "dendritic cells: 398.6" "Cell line enhanced" "Detected in many" "BJ: 2309.6;fHDF/TERT166: 1289.0;hTERT-RPE1: 1399.1" "HPA047089, HPA053624" Approved NA NA 140000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (5.56e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (3.34e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-2)" "unprognostic (1.18e-3)" "unprognostic (6.56e-3)" "unprognostic (2.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.51e-10)" "unprognostic (1.43e-2)" "unprognostic (8.33e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-2)" 331.1 285.0 88.0 411.0 89.8 16.7 260.8 92.5 117.3 651.3 127.3 3498.4 217.7 1928.1 201.9 1018.0 849.7 442.4 788.5 84.8 81.1 144.0 41.0 283.1 62.2 86.1 79.2 388.4 73.7 24.1 82.6 142.3 80.5 1219.0 238.0 8.0 393.6 1988.7 39012.3 148.5 636.2 2340.8 78.6 140.1 1252.6 82.9 83.3 26.3 138.9 16773.7 21.2 1630.1 454.9 79.8 375.4 291.2 213.9 33.6 335.4 893.3 129.3 2309.6 934.4 983.0 667.9 12.2 24.2 0.4 213.0 1289.0 144.6 9.2 3.7 291.2 457.0 716.2 10.8 9.1 1054.1 11.8 540.2 2.3 102.7 1067.7 44.9 738.8 0.4 1399.1 235.7 25.3 5.6 0.8 1052.1 15.3 2.7 29.1 269.6 1.5 17.0 18.5 391.5 3.0 31.1 7.2 3.8 13.3 470.0 7.9 18.2 273.8 6.8 27.7 30.0 16.5 585.7 11.6 730.6 0.6 2.7 2.9 34.0 6.5 29.2 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.3 0.4 0.0 0.1 0.0 0.4 0.2 0.0 398.6 0.0 2.1 88.0 89.8 92.5 117.3 84.8 81.1 86.1 79.2 80.5 78.6 83.3 79.8 110.0 3.2 4.1 10.4 5.9 57.1 81.2 274.1 24.5 0.8 29.9 1066.2 619.5 4.3 42.1 7.3 0.0 12.1 116.7 1.4 0.0 21.4 4.3 20.3 488.3 80.3 2.4 4.0 2.5 5.7 104.8 332.6 99.4 18.7 2.5 142.0 181.3 1.4 32.4 1.7 4.6 1.9 48.8 3.1 77.9 32.4 283.0 24.2 67.6 9.4 6.5 11.7 1.0 3.0 0.4 8.4 0.1 2072.1 2.9 169.8 0.4 1.3 23.5 0.9 2222.0 594.8 2341.4 2.5 27.3 6.7 42.8 14.6 16.0 106.7 2.8 28.7 TRAK1 "KIAA1042, MILT1, OIP106" ENSG00000182606 "Trafficking kinesin protein 1" Q9UPV9 3 42013802-42225890 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 168.9;skeletal muscle: 262.4;tongue: 202.6" "Cell type enhanced" "Detected in all" "Astrocytes: 173.0;Cardiomyocytes: 262.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RT4: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005853, HPA011367" Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" Nucleoplasm "HPA005853: AB_1854778, HPA011367: AB_2668495" "unprognostic (5.55e-2)" "unprognostic (1.38e-2)" "unprognostic (5.49e-2)" "unprognostic (2.52e-2)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (1.95e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" "unprognostic (3.01e-2)" "unprognostic (3.56e-3)" "prognostic favorable (4.84e-8)" "unprognostic (3.65e-2)" "unprognostic (1.70e-1)" "unprognostic (1.00e-2)" "unprognostic (4.61e-3)" 26.0 13.1 23.0 17.1 26.2 18.2 18.0 28.5 27.7 13.7 27.8 27.1 34.5 12.2 10.4 29.3 19.8 26.9 168.9 24.2 19.5 20.1 15.3 24.1 22.8 24.4 30.3 8.5 13.1 32.2 17.7 15.3 21.6 15.4 25.4 96.7 44.1 13.1 262.4 45.1 42.0 16.8 19.1 22.2 61.0 12.1 26.0 17.9 31.4 202.6 22.6 33.8 18.4 21.4 22.2 19.2 37.9 16.4 25.6 24.9 48.9 29.5 33.5 19.0 20.6 12.8 30.7 43.9 15.1 75.2 20.4 10.7 26.5 68.8 20.6 39.6 18.8 30.4 19.9 35.6 12.8 34.6 22.9 21.4 28.9 41.9 38.0 28.1 38.6 11.6 15.7 34.4 24.4 9.2 3.7 18.1 16.4 60.4 14.8 16.1 14.1 36.8 26.3 165.3 23.8 27.9 11.3 16.3 16.2 31.4 14.6 29.3 39.6 16.6 19.2 99.0 17.4 25.7 23.0 38.9 18.2 30.2 16.4 0.9 1.3 0.5 0.6 2.4 0.5 2.4 0.9 0.7 1.5 3.6 0.3 0.9 0.6 1.0 1.4 2.5 0.4 0.7 23.0 26.2 28.5 27.7 24.2 19.5 24.4 30.3 21.6 19.1 26.0 21.4 27.4 32.1 32.4 173.0 23.9 38.0 16.3 32.1 30.1 22.7 18.5 17.7 262.0 24.3 38.1 14.7 100.1 23.0 13.9 61.4 1.9 10.8 1.1 53.3 21.8 23.9 22.8 6.5 62.0 12.3 18.3 14.0 81.1 70.0 10.8 11.5 6.8 10.3 15.7 33.7 81.3 39.5 26.4 15.7 33.4 3.0 1.8 23.3 24.9 97.4 17.9 27.8 4.1 105.1 64.8 24.2 37.1 2.6 5.4 18.5 97.9 10.2 80.6 139.9 32.9 15.9 29.9 1.0 3.9 27.5 43.2 15.7 7.5 4.6 35.6 27.0 TRAK2 "ALS2CR3, CALS-C, GRIF-1, KIAA0549, MILT2, OIP98" ENSG00000115993 "Trafficking kinesin protein 2" O60296 2 201377207-201451500 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 157.8;Erythroid cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015827, HPA062163" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Nuclear bodies" Vesicles "HPA015827: AB_1858238, HPA062163: AB_2684702" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" "unprognostic (2.56e-2)" "unprognostic (4.31e-2)" "unprognostic (2.78e-1)" "unprognostic (1.76e-1)" "unprognostic (2.38e-2)" "unprognostic (3.08e-2)" "unprognostic (2.24e-1)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "prognostic favorable (7.42e-5)" "unprognostic (1.48e-1)" "unprognostic (3.24e-1)" "unprognostic (1.40e-2)" "unprognostic (9.82e-3)" 24.1 20.3 53.2 16.4 63.7 52.2 14.8 61.2 60.9 16.1 55.6 22.4 13.4 14.3 13.0 16.7 13.9 18.7 70.9 47.3 54.0 23.7 14.1 20.7 17.3 92.9 67.6 9.7 15.4 26.6 12.4 23.7 86.8 12.8 22.8 20.1 26.4 15.2 14.8 8.1 16.1 20.4 99.9 18.1 12.2 7.8 69.7 12.4 34.9 26.8 13.6 15.7 9.0 102.2 11.6 15.5 9.4 34.3 61.6 87.4 10.6 39.2 32.8 27.4 31.9 24.4 9.8 7.1 16.3 50.6 26.4 11.2 20.0 12.9 43.5 21.4 13.0 15.5 25.6 15.9 33.8 12.3 18.4 48.4 10.8 28.8 22.2 27.5 40.4 11.0 12.4 26.9 55.8 16.6 9.6 6.9 10.6 11.3 32.7 12.1 24.9 10.6 21.9 15.6 18.6 24.0 21.0 15.5 63.6 13.6 12.4 12.4 50.2 44.2 16.6 31.0 25.7 16.2 30.2 8.3 37.2 18.2 24.4 2.6 5.5 6.2 7.8 7.0 7.3 9.3 10.1 6.7 4.3 14.2 6.9 7.3 3.4 11.1 6.5 2.3 12.6 6.0 53.2 63.7 61.2 60.9 47.3 54.0 92.9 67.6 86.8 99.9 69.7 102.2 34.0 16.0 29.8 37.5 17.8 8.3 3.4 6.3 11.4 45.4 14.4 8.8 157.8 22.8 13.4 9.2 73.0 10.3 9.3 27.9 7.9 13.9 1.9 12.7 20.9 21.0 29.5 181.0 92.3 14.7 4.8 16.9 10.7 25.7 19.6 10.3 15.0 14.3 10.6 77.4 75.6 20.6 10.2 12.9 7.7 3.8 8.1 13.2 26.6 22.5 14.2 5.1 12.3 47.7 57.0 10.7 14.5 12.8 16.8 5.7 21.7 8.9 14.9 22.1 13.1 23.2 23.3 9.4 12.8 16.2 4.1 5.6 16.6 18.7 24.5 7.2 TRANK1 "KIAA0342, LBA1" ENSG00000168016 "Tetratricopeptide repeat and ankyrin repeat containing 1" O15050 3 36826819-36945057 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 45.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.5;Granulosa cells: 73.0;Inhibitory neurons: 91.8;Microglial cells: 52.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 115.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 115.1" "Cell line enhanced" "Detected in many" "Daudi: 67.9;HMC-1: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035508 Approved Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA035508: AB_10671105" "unprognostic (7.11e-3)" "unprognostic (1.55e-2)" "unprognostic (3.05e-2)" "unprognostic (2.34e-1)" "unprognostic (4.84e-2)" "unprognostic (2.04e-3)" "unprognostic (9.13e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-1)" "unprognostic (8.59e-2)" "unprognostic (3.83e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (1.82e-3)" "unprognostic (1.07e-3)" 7.4 4.6 1.7 14.0 2.5 10.0 6.4 5.2 7.5 24.6 0.0 14.8 11.1 18.0 5.2 3.2 45.0 9.6 6.2 1.8 2.3 3.4 9.9 8.8 18.7 1.9 0.5 15.6 2.4 3.2 6.7 5.2 1.8 16.5 13.4 1.4 6.8 6.3 1.1 2.3 16.7 8.8 3.4 13.1 8.2 2.4 3.3 17.5 6.2 2.5 20.8 16.6 10.0 0.7 1.4 1.7 0.4 0.0 4.5 17.9 0.0 1.4 9.1 3.9 8.0 0.0 7.2 67.9 2.8 5.3 13.5 0.5 0.2 1.0 0.7 3.7 0.1 11.6 4.8 0.0 5.5 3.1 26.1 5.7 3.5 3.1 0.2 1.1 5.4 7.6 9.5 9.9 2.4 0.1 8.9 1.3 0.5 0.0 1.9 2.5 0.3 1.4 1.5 3.3 0.6 0.0 7.2 1.9 0.7 0.8 1.2 3.8 3.7 3.4 1.3 0.2 1.2 9.3 2.2 15.8 0.6 2.6 0.4 7.3 2.0 11.5 14.9 2.9 10.7 10.9 12.3 15.3 1.4 17.5 11.0 10.6 115.1 8.5 3.9 0.2 11.6 3.0 1.7 2.5 5.2 7.5 1.8 2.3 1.9 0.5 1.8 3.4 3.3 0.7 5.4 16.0 7.8 18.3 18.8 0.8 1.3 1.7 6.8 4.4 1.6 2.3 3.6 1.5 4.0 3.7 2.1 1.3 16.5 40.9 0.0 3.1 0.4 6.1 15.1 5.5 5.4 12.6 56.5 1.8 1.6 7.1 18.8 8.8 6.3 73.0 5.7 17.7 5.0 0.0 91.8 16.7 0.0 6.6 0.8 0.0 4.4 7.4 5.4 52.5 8.7 1.6 26.8 23.6 13.2 3.2 16.9 6.0 21.9 1.6 16.7 0.9 5.2 0.7 0.0 2.6 5.2 0.3 0.3 2.6 0.9 0.7 21.8 3.7 4.0 1.5 TRAPPC9 "IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120" ENSG00000167632 "Trafficking protein particle complex 9" Q96Q05 8 139727725-140458579 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 89.5;Excitatory neurons: 121.8;Inhibitory neurons: 136.3;Late spermatids: 119.0;Microglial cells: 105.9;Oligodendrocyte precursor cells: 93.5;Oligodendrocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026579 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA026579: AB_1854459" "unprognostic (1.82e-2)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-2)" "unprognostic (2.30e-1)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (8.14e-2)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.76e-2)" "unprognostic (2.31e-1)" "prognostic favorable (5.11e-6)" "unprognostic (2.09e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.62e-1)" 8.6 13.4 10.3 6.9 11.0 11.1 8.9 10.7 12.7 10.3 12.5 11.1 8.0 11.3 5.1 12.3 12.2 5.8 15.0 10.8 10.3 13.8 11.6 9.5 8.0 13.1 14.1 10.5 11.9 27.4 20.7 7.2 13.9 11.7 6.0 14.2 11.6 8.3 33.5 11.4 10.9 7.2 10.2 11.3 12.5 9.0 11.9 11.3 12.9 17.6 6.8 11.1 10.8 13.0 9.6 16.6 7.4 20.8 15.5 9.0 4.9 6.0 9.9 3.1 5.0 6.2 11.2 11.6 14.0 11.9 4.7 12.2 10.0 9.4 3.4 16.8 6.1 18.6 9.8 6.2 11.2 4.7 14.5 8.9 9.3 2.5 7.9 11.1 12.9 13.1 6.7 10.1 5.1 27.0 29.2 6.2 2.3 31.3 14.0 12.2 2.7 19.4 11.6 11.6 19.1 10.6 9.8 4.7 10.6 7.6 15.3 6.8 7.7 4.6 7.9 10.8 4.9 14.1 10.9 7.8 9.6 10.1 7.4 15.4 3.5 2.9 4.2 3.3 4.6 2.7 2.9 3.3 3.5 4.4 2.8 3.6 5.0 4.9 3.4 4.2 2.1 3.5 10.3 11.0 10.7 12.7 10.8 10.3 13.1 14.1 13.9 10.2 11.9 13.0 5.1 3.2 8.3 89.5 9.6 2.3 4.7 3.1 5.7 14.2 5.5 4.1 13.9 5.7 5.3 11.0 20.9 10.9 5.4 15.2 9.8 6.5 47.9 8.4 3.7 6.5 30.5 3.4 121.8 6.2 4.4 5.3 29.6 10.2 8.8 7.9 4.6 9.2 7.5 28.6 136.3 14.4 10.2 10.5 3.7 119.0 5.9 10.3 10.6 105.9 5.3 13.6 11.3 93.5 170.6 5.1 6.6 7.9 11.0 3.7 13.4 19.9 15.7 13.7 6.6 9.0 5.3 3.6 6.6 8.7 3.0 14.6 10.5 8.6 12.0 5.4 TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 79.8" "Cell type enriched" "Detected in some" 10 "T-cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 395.1" "Group enriched" "Detected in many" 155 "granulocytes: 395.1;T-cells: 313.1" "Group enriched" "Detected in some" 25 "JURKAT: 29.9;MOLT-4: 76.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: AB_1080375, HPA072760: " "unprognostic (1.54e-4)" "unprognostic (1.41e-3)" "unprognostic (6.82e-2)" "unprognostic (4.95e-3)" "unprognostic (2.84e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (2.02e-2)" "unprognostic (7.21e-3)" "unprognostic (8.96e-3)" "unprognostic (8.03e-2)" "unprognostic (4.32e-1)" "unprognostic (2.86e-5)" "unprognostic (3.12e-1)" "unprognostic (3.01e-2)" "unprognostic (2.90e-4)" "unprognostic (4.36e-2)" 1.1 0.6 0.0 11.0 0.0 2.7 0.8 0.0 0.0 0.4 0.0 1.3 1.4 0.4 0.4 1.0 0.3 2.5 0.4 0.1 0.0 0.3 1.3 2.1 23.9 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.8 1.5 0.0 0.6 0.1 0.1 0.6 3.0 0.5 0.0 8.5 2.4 0.4 0.0 79.8 0.4 0.4 12.4 2.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 2.1 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 395.1 0.6 0.2 57.0 0.2 116.4 1.0 229.5 119.6 0.3 0.4 313.1 77.7 3.5 2.2 0.7 0.8 111.1 139.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.0 3.3 8.4 0.1 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 1.8 0.0 0.0 8.9 0.1 0.0 0.0 2.3 0.1 0.1 1.1 0.0 2.7 0.1 0.0 0.0 1.7 7.7 0.1 2.5 0.0 1.8 0.6 0.2 0.0 0.2 0.0 0.0 1.0 12.2 2.2 0.0 1.8 3.6 0.0 3.2 0.0 3.1 0.0 0.2 0.0 0.0 0.0 5.1 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.8 0.0 0.1 0.0 8.0 0.1 129.3 0.6 0.0 0.2 TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1520.1" "Group enriched" "Detected in many" 10 "dendritic cells: 338.0;NK-cells: 580.9;T-cells: 399.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 3232.4" "Lineage enriched" "Detected in all" 9 "T-cells: 3232.4" "Cell line enriched" "Detected in some" 5 "JURKAT: 1467.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.08e-4)" "unprognostic (7.96e-4)" "unprognostic (6.02e-2)" "unprognostic (1.26e-4)" "unprognostic (1.81e-2)" "unprognostic (5.42e-5)" "unprognostic (1.76e-2)" "unprognostic (6.94e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.56e-1)" "unprognostic (3.18e-6)" "unprognostic (3.98e-1)" "unprognostic (8.83e-3)" "unprognostic (1.02e-1)" "unprognostic (4.19e-3)" 9.2 5.1 1.3 140.0 1.5 53.5 9.5 1.1 2.1 7.7 1.5 18.5 26.8 6.4 5.7 12.0 7.0 26.7 5.0 1.0 1.1 5.4 11.4 31.5 322.2 2.0 1.2 6.4 2.7 0.9 2.0 2.3 1.7 9.0 19.4 0.0 19.0 4.6 1.0 9.9 49.7 4.2 1.7 92.5 27.1 2.7 1.6 1520.1 8.4 2.1 227.0 33.2 6.2 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 1467.5 2.0 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 296.5 2.0 0.0 1.9 0.0 45.6 7.2 4.7 869.6 3.5 693.8 17.1 1893.1 1259.3 5.8 15.7 1989.8 1450.7 37.3 359.8 8.3 9.7 3232.4 1917.5 1.3 1.5 1.1 2.1 1.0 1.1 2.0 1.2 1.7 1.7 1.6 1.9 7.3 19.2 40.8 0.0 11.7 0.0 0.3 0.0 0.0 0.0 5.9 5.5 0.0 0.0 3.1 1.8 0.0 0.2 338.0 0.0 0.0 0.5 0.6 1.1 0.7 1.5 0.0 10.7 0.0 0.0 0.1 3.2 4.6 0.8 20.2 0.0 5.3 1.5 0.3 0.0 0.0 0.1 0.0 8.4 0.0 1.9 17.4 13.9 0.0 0.0 17.3 0.0 580.9 0.0 0.0 0.0 0.1 8.2 23.6 0.3 0.0 2.4 0.7 0.0 0.0 1.1 3.5 0.0 0.1 0.5 0.0 0.1 399.0 0.1 0.1 0.4 TRBC2 TCRBC2 ENSG00000211772 "T cell receptor beta constant 2" 7 142801041-142802748 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 115.8;lymphoid tissue: 190.2" "Group enriched" "Detected in many" 4 "B-cells: 164.7;dendritic cells: 358.8;NK-cells: 264.7;T-cells: 498.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 76.0" "Lineage enriched" "Detected in many" 7 "T-cells: 76.0" "Cell line enriched" "Detected in some" 45 "MOLT-4: 277.9" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "prognostic favorable (8.04e-5)" "prognostic favorable (1.80e-4)" "unprognostic (4.19e-3)" "prognostic favorable (3.42e-8)" "unprognostic (5.53e-2)" "prognostic favorable (6.58e-5)" "unprognostic (3.21e-2)" "unprognostic (1.30e-2)" "prognostic favorable (2.81e-4)" "unprognostic (7.53e-3)" "unprognostic (5.96e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (4.09e-3)" 18.9 3.1 0.4 3.9 0.3 1.5 8.6 0.1 1.2 11.9 0.1 21.2 1.7 8.7 0.0 14.6 15.7 2.2 4.9 0.3 0.0 9.6 12.7 32.3 8.6 0.2 0.3 18.3 3.5 0.1 4.0 0.0 0.2 14.2 2.7 0.0 7.9 0.1 3.3 6.5 115.8 0.5 0.1 190.2 16.9 8.7 0.3 109.2 16.4 1.2 10.9 14.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 3.5 0.0 0.0 0.0 0.0 277.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 35.0 8.1 47.6 47.3 0.3 7.7 46.6 40.3 2.0 10.5 0.1 0.0 76.0 42.4 0.4 0.3 0.1 1.2 0.3 0.0 0.2 0.3 0.2 0.1 0.3 0.1 8.3 9.6 52.4 0.0 164.7 0.0 0.3 0.0 1.8 0.1 6.2 9.7 4.8 5.7 3.7 1.8 0.0 0.4 358.8 1.4 0.0 2.9 1.0 1.1 0.8 4.0 0.0 16.6 0.0 1.3 0.1 10.8 8.6 0.9 20.2 0.0 15.0 1.6 0.4 0.0 0.0 0.8 0.0 9.0 0.0 4.2 63.6 18.9 0.0 0.0 19.0 15.6 264.7 0.0 0.0 20.1 0.1 70.3 30.6 0.4 0.1 2.2 2.9 0.4 65.7 4.2 12.4 0.1 0.8 1.3 0.0 0.3 498.0 1.4 0.9 0.2 TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 1014.1" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Group enriched" "Detected in some" 4 "hTCEpi: 74.6;THP-1: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" 10.7 13.2 28.1 3.5 31.1 0.2 9.8 33.7 61.5 6.5 29.1 3.5 0.9 1.6 2.3 0.6 7.4 9.7 2.1 27.5 32.3 1.3 2.3 30.1 2.6 44.5 34.4 2.4 3.9 7.4 3.9 10.7 42.7 2.0 4.3 1.9 6.0 3.1 0.4 0.5 1.4 4.5 46.7 0.5 2.5 0.7 43.5 1.8 1.7 0.0 0.4 4.5 0.6 69.8 0.0 0.3 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 1.2 74.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 42.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 28.1 31.1 33.7 61.5 27.5 32.3 44.5 34.4 42.7 46.7 43.5 69.8 1.8 6.4 7.5 0.0 0.7 0.8 0.2 79.8 0.0 0.3 1.8 58.8 0.1 1.5 9.6 0.0 0.0 5.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 0.0 0.0 0.0 4.9 1.2 0.0 0.0 2.5 0.0 2.2 0.2 1014.1 0.0 0.0 0.0 2.0 34.7 5.2 1.0 0.6 120.5 0.0 12.2 8.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.3 1.0 6.6 0.1 1.0 0.0 0.0 0.0 0.1 7.3 0.8 0.0 0.0 0.1 TRGC2 "TCRGC2, TRGC2(2X), TRGC2(3X)" ENSG00000227191 "T cell receptor gamma constant 2" 7 38239580-38249572 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 30.5;lymphoid tissue: 34.6;prostate: 23.7" "Group enriched" "Detected in some" 7 "dendritic cells: 149.1;NK-cells: 90.6;T-cells: 122.0" "Cancer enriched" "Detected in many" 18 "prostate cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 720.5" "Lineage enriched" "Detected in many" 5 "T-cells: 720.5" "Cell line enhanced" "Detected in some" "HL-60: 11.4;JURKAT: 36.6;NB-4: 29.9;SK-BR-3: 9.8;U-937: 53.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.79e-3)" "prognostic favorable (1.06e-5)" "unprognostic (1.62e-4)" "unprognostic (3.52e-5)" "unprognostic (3.34e-1)" "unprognostic (1.46e-3)" "unprognostic (8.79e-4)" "unprognostic (4.60e-2)" "unprognostic (1.10e-2)" "unprognostic (1.91e-3)" "unprognostic (1.12e-1)" "unprognostic (3.90e-1)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-3)" 3.6 1.1 8.8 5.1 9.0 30.5 1.8 8.6 19.6 1.5 7.1 3.5 4.5 1.3 3.2 1.1 2.2 3.9 0.9 8.4 8.5 1.6 3.6 9.7 17.5 9.6 8.9 0.5 0.8 0.2 1.0 0.5 9.2 23.7 4.0 0.1 1.8 0.8 0.4 0.6 8.0 1.0 9.3 29.7 3.8 2.2 10.2 34.6 2.1 0.1 7.0 3.4 2.3 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 3.7 1.2 29.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.9 0.0 1.1 1.3 1.4 720.5 1.2 287.4 0.6 64.8 341.6 1.0 0.3 13.5 212.9 4.9 149.7 1.0 1.2 1.3 167.5 8.8 9.0 8.6 19.6 8.4 8.5 9.6 8.9 9.2 9.3 10.2 9.5 1.2 0.0 2.4 0.0 2.4 0.0 0.2 0.0 0.0 0.0 1.0 1.3 0.7 1.5 0.6 0.0 0.0 0.0 149.1 0.3 0.0 0.2 15.5 0.2 0.1 0.8 0.0 6.6 0.0 0.0 0.0 0.4 2.6 0.2 0.0 0.2 3.9 1.0 0.0 0.0 0.0 0.5 0.0 3.5 0.0 6.7 0.0 2.8 0.0 0.0 10.6 0.0 90.6 0.0 0.0 0.0 0.0 0.4 14.2 2.8 0.0 0.5 0.0 0.0 0.0 0.2 1.3 0.8 0.2 0.3 0.0 0.3 122.0 0.0 0.2 0.3 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 104.3;Muller glia cells: 100.3" "Cancer enhanced" "Detected in all" "melanoma: 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.8" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.8" "Cell line enhanced" "Detected in many" "AN3-CA: 183.5;HEL: 185.7;K-562: 258.0;SK-MEL-30: 189.3;WM-115: 246.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 43.3 63.1 29.1 38.9 29.9 16.8 38.3 36.1 35.2 21.7 30.5 27.0 17.8 44.4 43.4 15.5 23.4 28.8 51.0 31.6 37.7 92.3 21.0 39.8 72.7 31.4 30.8 97.8 26.2 18.0 20.0 46.6 29.7 33.0 13.4 137.8 20.4 25.6 14.3 16.9 25.2 34.2 29.7 79.7 41.8 28.5 32.4 39.3 23.9 19.5 69.6 48.4 19.5 28.0 0.2 0.4 138.8 183.5 48.9 44.7 0.2 7.9 7.5 4.9 7.9 0.9 15.3 16.3 5.5 16.9 0.8 2.3 10.3 16.1 4.2 18.3 28.9 185.7 0.4 2.7 60.7 10.7 68.0 41.7 16.0 20.3 5.6 48.9 22.1 23.8 258.0 0.3 7.9 1.7 24.4 44.8 66.1 7.0 18.0 0.0 46.2 6.7 31.9 23.4 118.9 56.6 1.1 7.4 189.3 41.4 0.2 1.1 13.9 65.3 32.0 0.6 17.8 0.1 0.2 22.9 35.2 36.3 246.7 1.7 0.2 3.2 12.7 0.0 15.8 9.6 26.1 13.8 1.2 12.2 15.0 9.2 0.5 19.3 0.2 0.1 48.8 8.9 29.1 29.9 36.1 35.2 31.6 37.7 31.4 30.8 29.7 29.7 32.4 28.0 52.2 3.2 8.3 25.5 12.5 6.1 9.1 26.9 19.4 55.0 7.9 8.6 17.1 12.8 15.6 16.5 31.3 2.6 17.5 0.7 7.9 17.2 4.3 9.7 11.6 43.9 0.0 22.1 13.5 104.3 0.2 11.3 20.9 15.9 34.2 77.3 59.6 6.7 5.8 20.2 6.9 0.4 28.5 5.1 8.2 14.3 77.3 3.8 30.2 13.1 3.0 100.3 26.8 59.8 2.7 45.3 0.2 74.4 21.0 11.6 0.3 1.0 17.9 66.7 52.6 9.9 41.2 1.0 6.0 5.7 5.4 0.8 27.1 30.5 0.8 32.5 TRIM59 "Mrf1, RNF104, TRIM57, TSBF1" ENSG00000213186 "Tripartite motif containing 59" Q8IWR1 3 160432445-160485773 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 68.4" "Cell type enriched" "Detected in many" 12 "Oligodendrocytes: 391.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017750 Uncertain Approved "Rods & Rings" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Rods & Rings" "HPA017750: AB_1858312" "unprognostic (3.74e-1)" "prognostic favorable (4.36e-4)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-1)" "unprognostic (8.00e-4)" "unprognostic (1.88e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.02e-3)" "unprognostic (2.44e-11)" "unprognostic (7.92e-2)" "unprognostic (2.42e-1)" "unprognostic (4.03e-2)" "unprognostic (5.91e-3)" 0.7 0.8 9.0 5.1 38.8 17.6 2.1 18.0 20.4 1.4 0.0 2.7 2.8 3.0 0.9 4.9 2.0 2.7 0.8 12.3 15.2 1.2 1.0 2.0 12.1 19.4 23.6 1.3 1.5 1.8 1.2 2.0 19.9 2.0 2.6 1.4 1.7 1.0 1.2 5.4 2.9 2.8 9.3 5.1 2.5 8.7 24.6 13.6 2.0 0.1 12.1 3.1 2.2 68.4 20.4 15.8 19.8 1.3 7.8 10.6 26.0 31.5 27.3 38.5 36.9 1.9 34.8 54.5 22.9 23.7 12.1 34.1 0.0 12.9 50.7 49.1 19.2 2.0 5.4 2.4 10.9 24.3 3.2 9.0 3.8 18.7 13.4 23.6 27.1 8.0 25.8 22.6 36.7 21.9 15.0 1.9 52.5 13.2 26.1 20.7 17.2 24.6 13.8 6.6 13.0 2.8 9.0 26.3 0.7 26.5 31.2 22.4 20.9 2.8 8.9 4.5 3.1 37.0 14.5 13.4 3.4 31.0 3.1 29.1 2.8 5.4 10.9 3.1 12.7 10.4 17.9 15.0 4.5 9.3 12.0 14.5 2.2 12.4 1.5 6.7 22.0 3.7 9.0 38.8 18.0 20.4 12.3 15.2 19.4 23.6 19.9 9.3 24.6 68.4 0.6 0.0 6.5 0.3 7.8 4.8 4.7 2.1 3.4 0.4 2.8 1.8 2.5 2.8 1.4 1.8 6.2 7.2 6.1 1.2 0.0 2.0 31.2 1.9 2.1 2.5 10.8 29.5 0.4 2.0 11.7 2.1 5.1 2.9 1.3 10.1 2.2 0.1 2.9 0.0 0.5 2.9 2.0 2.2 2.3 12.5 0.3 1.8 3.6 0.0 2.1 0.5 3.1 0.0 391.8 1.9 2.8 0.7 6.4 3.3 1.2 2.3 2.1 1.7 0.0 2.4 2.7 14.0 15.1 5.6 4.4 2.5 10.9 2.7 4.8 3.6 TRIM69 "RNF36, Trif, TRIMLESS" ENSG00000185880 "Tripartite motif containing 69" Q86WT6 15 44728988-44767829 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 35.0" "Cell type enhanced" "Detected in all" "Early spermatids: 213.2;Late spermatids: 93.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "T-reg: 4.2" "Lineage enriched" "Detected in single" 7 "T-cells: 4.2" "Cell line enhanced" "Detected in some" "Karpas-707: 2.4;U-266/70: 8.2;U-266/84: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA028894 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA028894: AB_10603136" "unprognostic (4.82e-3)" "unprognostic (1.23e-2)" "unprognostic (4.10e-1)" "unprognostic (2.01e-1)" "unprognostic (1.75e-2)" "unprognostic (4.20e-1)" "unprognostic (9.27e-2)" "unprognostic (4.95e-2)" "unprognostic (6.49e-2)" "unprognostic (3.53e-3)" "unprognostic (1.38e-1)" "unprognostic (3.72e-2)" "prognostic favorable (2.26e-5)" "unprognostic (4.79e-2)" "unprognostic (1.82e-1)" "unprognostic (1.91e-2)" "unprognostic (1.49e-2)" 0.8 0.8 5.2 0.4 5.2 0.2 0.8 4.7 7.1 0.9 4.5 1.2 0.4 0.6 0.4 0.7 0.8 0.5 2.8 5.0 5.1 1.6 1.5 1.3 0.9 5.2 5.0 0.8 0.4 0.3 1.5 0.2 5.1 0.8 0.5 0.6 0.8 0.2 5.9 1.0 1.3 0.6 5.0 2.4 0.7 35.0 5.0 0.5 0.6 6.0 1.2 0.7 0.8 5.4 0.1 0.1 0.2 0.6 0.2 0.7 0.0 0.1 0.3 0.8 1.3 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 1.7 0.0 0.2 0.1 0.0 0.7 0.0 0.1 0.9 0.6 0.1 0.1 1.1 0.2 0.7 0.0 2.4 0.2 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.2 8.2 2.3 1.4 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.6 0.6 0.8 0.9 0.0 0.0 0.2 0.6 0.1 0.0 0.2 0.0 4.2 0.1 5.2 5.2 4.7 7.1 5.0 5.1 5.2 5.0 5.1 5.0 5.0 5.4 41.8 6.4 5.1 9.4 22.1 21.3 21.3 8.0 12.0 10.8 9.3 9.1 60.2 8.6 11.0 9.2 4.2 6.1 20.4 16.5 41.1 42.1 213.2 9.0 12.2 22.2 4.2 5.7 16.0 16.0 4.2 17.8 13.7 10.6 14.0 10.5 11.4 5.1 36.3 23.5 9.8 7.5 8.2 25.4 39.7 93.9 9.3 22.6 12.4 1.0 52.7 21.2 20.6 9.5 1.7 14.8 13.4 11.7 21.9 11.4 18.6 27.0 8.8 4.2 6.6 27.0 19.7 78.8 1.7 25.0 41.2 1.5 25.6 5.1 7.0 52.5 TRIQK "C8orf83, DKFZp779L1068, LOC286144, PRO0845" ENSG00000205133 "Triple QxxK/R motif containing" Q629K1 8 92883532-93017673 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 32.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.47e-3)" "unprognostic (3.09e-1)" "unprognostic (6.03e-3)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (5.13e-2)" "unprognostic (7.78e-2)" "unprognostic (2.50e-1)" "unprognostic (2.31e-1)" "unprognostic (1.56e-1)" "unprognostic (2.52e-1)" "unprognostic (1.79e-1)" "unprognostic (5.11e-3)" "unprognostic (9.23e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-2)" 12.8 21.9 12.3 7.7 15.7 14.5 14.5 18.6 14.9 19.4 10.5 20.7 12.4 12.5 9.7 9.8 15.7 22.9 20.1 13.7 13.5 19.4 31.3 17.0 5.3 13.4 12.6 19.6 18.0 20.6 10.7 19.6 14.0 18.1 21.0 12.4 11.1 10.2 2.4 5.7 12.1 11.4 14.2 13.2 17.5 6.5 13.5 7.3 23.4 5.6 5.2 15.5 7.9 17.0 7.4 9.2 19.8 7.0 27.1 42.8 6.6 26.4 28.4 14.7 20.9 1.3 22.9 0.0 31.6 24.9 9.8 11.9 16.1 15.9 23.7 0.0 7.6 28.9 10.1 15.6 22.9 8.1 24.0 32.0 35.4 8.0 27.1 33.3 15.7 16.3 5.6 16.7 21.3 19.7 13.1 6.3 6.8 31.3 33.8 0.0 20.5 9.6 27.8 9.1 11.4 16.0 10.0 3.9 25.6 16.3 27.2 7.1 20.5 21.8 6.7 38.3 8.3 5.8 0.0 0.0 33.8 0.1 22.5 0.9 17.0 15.9 0.1 18.8 8.1 2.8 0.9 0.7 9.4 1.9 0.0 0.0 14.6 2.0 32.9 2.5 0.2 4.7 12.3 15.7 18.6 14.9 13.7 13.5 13.4 12.6 14.0 14.2 13.5 17.0 19.0 19.2 17.9 21.9 4.0 15.0 21.4 17.1 22.8 18.9 17.7 12.4 13.8 25.8 14.1 16.5 6.2 7.3 2.1 16.2 50.9 14.8 7.0 21.3 27.7 17.8 19.2 6.7 36.8 16.4 23.8 23.5 20.9 24.5 2.5 11.7 17.2 18.3 11.9 6.7 43.6 35.6 12.2 20.0 13.6 8.0 16.4 18.5 23.2 31.9 24.3 22.8 3.1 34.7 56.3 12.5 14.0 21.8 1.0 22.2 17.0 39.1 29.5 6.3 32.9 18.4 18.2 12.1 5.3 12.3 8.4 3.7 3.3 21.6 20.0 22.6 TRPM6 "CHAK2, FLJ22628, HOMG, HSH" ENSG00000119121 "Transient receptor potential cation channel subfamily M member 6" Q9BX84 9 74722495-74888094 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 6.6;intestine: 16.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 128.9;Glandular and luminal cells: 36.5;Microglial cells: 39.4;Oligodendrocytes: 81.1;Proximal enterocytes: 23.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 23.1;neutrophil: 7.5" "Lineage enriched" "Detected in single" 41 "granulocytes: 23.1" "Cell line enhanced" "Detected in some" "BEWO: 3.8;HeLa: 2.4;Karpas-707: 1.3;RT4: 3.8;U-266/70: 1.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (7.80e-2)" "unprognostic (9.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (5.72e-4)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (8.10e-2)" "unprognostic (7.54e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-2)" 0.6 0.0 2.1 0.6 3.5 2.6 0.6 3.0 2.4 0.3 0.2 13.2 7.0 0.3 0.2 0.3 0.2 0.3 0.2 1.6 2.8 1.9 0.1 0.3 0.3 4.2 3.4 0.0 0.1 1.4 0.5 0.3 4.1 0.5 16.6 0.4 0.3 0.1 0.1 0.7 7.9 0.5 2.7 0.5 0.2 1.4 3.1 0.4 0.2 0.1 0.3 0.4 0.3 6.6 0.0 0.8 0.1 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 1.0 0.1 0.3 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.1 0.1 2.4 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.1 0.0 1.4 0.0 0.1 0.0 0.1 0.1 23.1 0.1 2.4 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 7.5 0.5 0.2 0.3 0.0 0.1 2.1 3.5 3.0 2.4 1.6 2.8 4.2 3.4 4.1 2.7 3.1 6.6 3.3 0.0 1.7 1.0 0.3 0.1 1.9 0.3 2.2 0.3 0.2 0.4 0.9 0.0 1.3 3.7 0.0 0.2 0.2 128.9 0.0 0.0 4.0 11.3 3.4 3.2 3.6 0.0 1.3 0.0 0.1 0.3 0.0 36.5 0.0 0.1 3.3 0.1 0.0 0.0 0.5 3.0 0.0 0.3 0.6 0.9 0.0 0.4 0.0 39.4 0.0 0.3 0.0 0.5 81.1 0.0 13.8 0.4 0.1 1.3 23.3 0.0 0.8 2.7 0.0 0.7 0.4 1.6 2.4 0.5 1.0 0.1 0.5 0.2 7.5 0.8 TRPS1 "GC79, LGCR" ENSG00000104447 "Transcriptional repressor GATA binding 1" Q9UHF7 8 115408496-115809673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 60.8" "Cell type enhanced" "Detected in many" "Astrocytes: 758.7;Breast glandular cells: 243.2;Oligodendrocyte precursor cells: 280.5;Oligodendrocytes: 294.0" "Cancer enriched" "Detected in many" 8 "breast cancer: 49.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 47.4;SK-BR-3: 78.1;T-47d: 244.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060380, HPA071767" Enhanced Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA060380: AB_2684270, HPA071767: AB_2732185" "unprognostic (4.34e-2)" "unprognostic (4.65e-2)" "unprognostic (1.73e-2)" "unprognostic (2.57e-1)" "unprognostic (1.87e-1)" "prognostic favorable (9.42e-4)" "unprognostic (2.23e-3)" "unprognostic (2.08e-1)" "unprognostic (9.31e-2)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (3.02e-1)" "unprognostic (2.17e-2)" "unprognostic (1.93e-2)" "unprognostic (1.64e-1)" "unprognostic (1.78e-2)" "unprognostic (3.07e-3)" 4.4 3.1 15.5 5.7 14.3 7.6 60.8 10.5 14.7 10.9 10.1 5.9 0.9 9.9 3.4 14.2 5.5 10.0 3.8 17.0 13.5 5.4 2.1 4.7 4.9 32.5 31.5 5.2 1.1 5.3 2.6 2.8 24.2 9.4 2.7 4.1 12.0 8.4 2.6 10.6 2.1 10.6 18.4 4.2 2.7 12.5 27.5 2.4 5.7 3.3 4.0 5.1 14.1 16.3 3.1 0.6 5.9 0.3 5.4 19.8 0.6 4.9 11.3 3.1 5.2 0.5 4.9 2.4 0.0 12.7 2.6 0.1 22.9 4.3 3.5 0.3 6.9 0.1 10.3 0.2 7.2 0.0 0.3 9.5 4.4 8.6 15.8 8.9 2.7 0.3 1.1 37.7 6.0 47.4 0.2 0.0 1.1 1.1 4.8 0.2 0.2 30.0 4.9 0.3 5.2 3.9 2.5 78.1 3.2 2.8 244.8 2.1 0.2 13.7 6.9 4.0 9.7 10.1 0.3 4.5 14.4 0.0 9.2 0.0 4.5 0.0 0.9 1.9 0.9 0.5 1.0 1.0 1.7 0.8 0.9 0.9 0.8 1.0 1.4 0.6 0.5 0.8 15.5 14.3 10.5 14.7 17.0 13.5 32.5 31.5 24.2 18.4 27.5 16.3 10.0 6.4 3.0 758.7 13.3 9.4 20.0 10.3 34.1 9.2 243.2 125.1 4.6 2.8 9.2 18.4 43.8 0.1 18.7 0.1 11.7 2.9 95.0 58.5 35.7 7.5 0.0 5.5 128.3 2.9 0.2 26.8 4.6 63.5 12.7 0.3 3.6 1.1 16.5 0.0 148.2 0.0 8.2 55.2 104.1 163.2 25.1 55.5 21.4 171.4 32.5 10.6 5.2 280.5 294.0 2.7 0.0 28.2 10.1 16.9 0.0 23.7 8.9 35.9 6.6 60.2 28.2 1.8 8.3 73.6 12.5 0.3 25.6 19.5 0.0 11.2 TRPV4 "CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC" ENSG00000111199 "Transient receptor potential cation channel subfamily V member 4" Q9HBA0 12 109783087-109833406 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Charcot-Marie-Tooth disease, Disease variant, Dwarfism, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 50.8;salivary gland: 19.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 17.1;Cholangiocytes: 20.0;Cytotrophoblasts: 20.0;Kupffer cells: 19.6;Respiratory ciliated cells: 28.2;Syncytiotrophoblasts: 21.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 5 "hippocampal formation: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 7.9;BJ hTERT+: 9.5;EFO-21: 7.2;HaCaT: 14.2;HUVEC TERT2: 8.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007150 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA007150: AB_1080393" "unprognostic (2.98e-2)" "unprognostic (1.12e-2)" "unprognostic (2.33e-2)" "unprognostic (4.20e-3)" "unprognostic (6.25e-3)" "unprognostic (1.09e-2)" "unprognostic (7.95e-2)" "unprognostic (2.03e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "prognostic favorable (4.12e-5)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" 1.0 0.8 0.2 0.9 0.3 0.1 1.9 0.7 0.5 2.0 50.8 0.4 0.7 0.6 0.4 10.3 4.7 1.4 0.8 4.2 0.2 14.7 8.6 2.2 0.8 0.5 0.4 0.3 4.4 0.3 2.1 5.2 0.3 6.8 0.3 0.0 19.2 0.8 0.1 7.5 0.4 0.7 0.2 2.8 0.7 0.8 0.8 0.1 0.9 0.0 0.9 1.8 2.2 0.4 2.4 0.2 0.0 0.0 2.0 1.2 7.9 4.2 9.5 1.2 0.3 0.0 6.4 0.0 7.2 5.8 0.0 14.2 1.0 0.0 0.4 0.0 1.8 0.0 0.1 3.7 0.6 0.0 0.0 3.4 2.0 2.7 0.0 0.6 8.7 0.0 0.5 0.0 0.4 5.3 0.0 0.0 1.5 0.0 0.0 0.0 0.5 0.0 0.0 4.9 0.0 0.0 0.3 0.6 2.6 3.5 1.1 0.2 4.5 0.0 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.5 4.2 0.2 0.5 0.4 0.3 0.2 0.8 0.4 0.1 0.0 0.0 0.0 0.7 3.3 8.1 17.1 7.4 0.0 5.1 5.5 1.0 20.0 12.0 11.0 0.0 20.0 0.4 0.0 3.9 2.5 0.2 3.2 1.0 1.4 0.0 0.0 0.3 9.3 5.3 1.2 2.0 1.2 0.0 0.9 0.7 7.7 4.0 0.0 0.4 0.0 6.1 19.6 0.7 0.2 0.9 2.6 7.2 1.9 0.8 0.0 0.0 1.0 0.3 2.0 0.0 0.0 0.0 4.6 0.0 12.5 28.2 0.0 0.0 0.1 1.1 0.3 1.1 4.5 3.8 21.1 0.3 0.2 0.0 3.3 TSEN34 "LENG5, SEN34, SEN34L" ENSG00000170892 "TRNA splicing endonuclease subunit 34" Q9BSV6 19 54189938-54194536 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Disease variant, Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 5.0;eosinophil: 1.9;neutrophil: 4.8" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041111, HPA048208" Approved Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA041111: AB_10794263, HPA048208: AB_2680313" "unprognostic (3.24e-2)" "unprognostic (2.95e-2)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (3.48e-2)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.44e-7)" "unprognostic (2.38e-1)" "unprognostic (7.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.04e-3)" "unprognostic (8.98e-2)" "unprognostic (4.55e-3)" "unprognostic (2.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.81e-1)" "unprognostic (1.12e-1)" 28.5 68.2 2.2 1.3 1.8 1.3 29.5 2.4 2.4 38.8 1.8 34.7 1.1 37.1 1.9 41.0 37.8 1.5 26.3 2.1 1.7 39.1 41.3 31.5 1.3 2.2 1.7 47.9 43.0 1.8 36.0 1.3 2.0 36.2 1.3 2.0 34.0 1.9 26.7 40.5 27.7 1.2 1.3 44.1 34.3 45.0 1.7 0.5 30.9 1.8 0.7 38.9 34.2 2.2 3.3 1.7 2.5 3.1 1.3 2.0 3.9 0.6 1.0 0.9 1.7 2.1 1.1 1.1 0.0 0.9 2.5 2.5 2.6 2.3 1.4 1.1 6.2 1.0 1.1 2.0 0.5 1.1 1.1 1.9 1.1 2.0 1.3 0.9 1.3 0.0 1.7 0.9 2.4 1.4 0.4 0.2 1.5 2.9 1.1 1.4 2.6 0.7 3.4 2.4 0.1 1.7 0.0 3.5 3.0 2.5 2.6 3.1 1.1 0.2 2.8 2.7 3.4 1.4 1.9 0.9 2.6 1.3 1.2 5.0 0.6 1.9 0.2 0.5 0.4 0.1 0.3 0.1 0.3 0.4 0.4 0.2 4.8 0.0 0.3 0.4 0.0 0.2 2.2 1.8 2.4 2.4 2.1 1.7 2.2 1.7 2.0 1.3 1.7 2.2 33.1 12.8 27.7 6.8 28.2 73.5 92.0 137.7 67.2 35.4 62.9 60.8 11.8 52.9 60.9 44.1 29.2 102.5 45.4 58.8 95.9 68.7 24.0 39.4 37.0 32.5 76.8 13.7 3.8 59.7 98.2 47.5 19.9 35.3 26.6 47.7 35.7 40.6 57.8 16.8 4.9 103.7 122.1 37.0 53.6 17.2 67.7 45.0 46.2 1.0 51.8 81.9 18.6 6.0 5.9 50.4 55.9 66.5 27.6 79.8 57.8 110.5 70.0 48.9 59.2 38.7 60.8 40.1 77.2 56.7 70.2 111.0 32.8 100.3 66.5 62.3 TSPAN11 ENSG00000110900 "Tetraspanin 11" A1L157 12 30926428-30996602 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 25.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.7;Inhibitory neurons: 5.7;Late spermatids: 10.6;Oligodendrocyte precursor cells: 27.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.2;HSkMC: 22.8;NTERA-2: 18.2;SCLC-21H: 9.7;SH-SY5Y: 18.6;SuSa: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066789 Approved Vesicles NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA066789: AB_2685723" "unprognostic (4.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.38e-3)" "unprognostic (1.18e-2)" "unprognostic (4.51e-1)" "prognostic favorable (5.28e-4)" "unprognostic (4.28e-2)" "prognostic favorable (3.43e-4)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (1.51e-2)" "unprognostic (3.03e-2)" "unprognostic (5.77e-3)" "unprognostic (2.04e-2)" "unprognostic (5.81e-2)" "unprognostic (2.90e-3)" "unprognostic (1.79e-1)" 2.5 2.1 5.5 7.5 5.1 0.0 1.9 9.3 5.0 6.5 0.8 25.9 3.9 1.7 5.8 3.5 1.9 7.1 6.5 5.0 3.9 1.0 0.7 3.4 2.2 4.5 5.7 0.8 1.1 0.1 1.0 0.7 3.7 4.1 8.8 1.4 2.4 4.8 0.4 5.6 9.6 6.4 2.3 2.4 3.8 1.0 6.3 0.8 3.1 1.2 4.1 4.5 3.6 4.8 0.0 0.3 25.2 0.0 0.1 0.3 0.2 0.3 0.8 0.0 0.0 0.0 0.8 0.0 1.4 2.2 0.1 0.6 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.1 22.8 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 18.2 0.0 0.2 0.1 0.1 0.5 0.0 0.1 9.7 18.6 0.2 0.0 0.1 11.2 0.0 0.0 0.0 0.1 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.1 9.3 5.0 5.0 3.9 4.5 5.7 3.7 2.3 6.3 4.8 0.6 0.0 0.0 3.6 0.0 0.8 0.0 0.0 0.0 1.7 0.1 0.0 2.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.5 2.4 3.3 0.0 0.0 1.5 0.0 0.0 4.3 0.0 0.4 0.0 0.2 5.7 0.2 0.1 0.0 5.7 0.0 0.0 0.0 1.7 10.6 4.7 0.2 1.8 1.0 0.0 3.6 0.0 27.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.9 0.5 0.0 0.3 1.1 0.2 0.5 0.1 1.1 0.0 0.2 0.1 0.0 0.1 TSPAN12 "NET-2, TM4SF12" ENSG00000106025 "Tetraspanin 12" O95859 7 120787320-120858402 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Collecting duct cells: 103.0;Distal tubular cells: 189.8;Glandular and luminal cells: 87.5;Proximal tubular cells: 111.1" "Cancer enhanced" "Detected in all" "renal cancer: 44.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 53.0;HUVEC TERT2: 58.3;RH-30: 52.2;RPTEC TERT1: 90.5;RT4: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051570, HPA058244" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Microtubules Vesicles "HPA051570: , HPA058244: AB_2683652" "unprognostic (2.40e-2)" "unprognostic (7.60e-2)" "unprognostic (3.66e-3)" "unprognostic (1.82e-2)" "unprognostic (3.97e-1)" "unprognostic (7.34e-3)" "unprognostic (1.60e-1)" "unprognostic (8.12e-2)" "unprognostic (1.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (9.53e-2)" "unprognostic (7.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.43e-1)" 11.9 65.9 4.1 5.3 4.4 0.4 8.7 5.2 5.2 21.4 2.8 24.0 39.4 10.5 14.9 5.0 10.9 20.4 47.7 3.3 4.7 91.6 35.8 45.8 4.5 8.0 6.2 1.7 17.4 10.7 7.5 20.3 5.2 6.8 20.4 1.8 46.8 22.4 3.3 1.6 42.0 11.9 4.6 28.2 22.1 3.9 8.1 2.7 23.4 5.5 4.3 17.5 4.0 3.6 0.0 1.4 15.1 0.2 3.1 1.0 14.7 0.3 0.6 1.2 5.0 2.5 4.0 0.0 10.4 0.4 1.8 0.2 7.7 1.6 1.9 0.0 53.0 2.8 14.5 2.2 8.1 0.1 2.5 0.3 0.0 0.4 0.3 2.1 58.3 0.0 0.7 1.8 6.8 2.0 0.2 0.4 24.5 11.1 9.4 0.1 52.2 2.0 90.5 65.4 12.5 7.4 0.7 1.3 0.0 20.0 8.0 1.9 2.5 12.3 3.8 0.1 6.5 15.8 0.0 0.2 1.7 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.4 5.2 5.2 3.3 4.7 8.0 6.2 5.2 4.6 8.1 3.6 40.0 118.6 45.0 18.6 1.7 2.5 20.3 1.8 14.8 0.0 19.4 3.8 62.5 64.3 19.9 103.0 0.0 40.5 0.0 18.0 189.8 6.8 0.6 63.4 9.0 38.0 9.6 2.7 1.8 7.2 53.5 10.0 14.8 87.5 2.5 1.8 18.2 32.9 4.1 0.0 2.9 16.9 6.1 0.8 3.6 1.5 4.1 1.5 5.4 3.7 0.0 0.5 0.0 10.1 0.4 4.7 30.5 0.7 2.2 9.1 68.3 111.1 5.7 0.1 0.0 11.6 16.6 0.6 8.9 13.8 2.0 24.2 1.9 9.6 35.5 28.3 TSPAN3 "TM4-A, TM4SF8, TSPAN-3" ENSG00000140391 "Tetraspanin 3" O60637 15 77041404-77083984 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 705.9;Muller glia cells: 508.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "memory B-cell: 481.0;naive B-cell: 488.1;plasmacytoid DC: 313.2" "Group enriched" "Detected in all" 5 "B-cells: 488.1;dendritic cells: 313.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015996 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA015996: AB_1858406" "unprognostic (5.94e-2)" "unprognostic (3.05e-1)" "unprognostic (7.32e-2)" "unprognostic (2.15e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (5.41e-3)" "unprognostic (3.51e-3)" "unprognostic (2.90e-2)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (3.79e-3)" "unprognostic (1.35e-1)" 333.8 143.9 257.2 87.3 248.9 33.3 143.3 253.4 292.4 138.2 288.7 364.2 342.1 130.9 432.8 78.4 249.8 186.2 108.8 247.8 296.3 211.3 87.4 202.1 88.0 250.0 267.7 148.1 140.2 283.4 189.7 111.6 260.2 96.2 386.3 418.6 152.2 187.3 429.1 78.3 349.2 128.3 266.7 84.8 221.2 84.8 282.5 71.6 200.3 374.4 106.9 170.1 67.4 281.3 130.6 347.6 282.8 179.3 484.7 295.8 93.3 203.7 220.2 245.1 265.7 213.5 264.7 126.9 294.8 211.6 234.0 289.0 271.2 139.5 182.9 143.4 410.4 91.0 252.5 204.4 234.5 118.4 64.3 280.9 165.5 135.8 120.1 372.6 304.8 83.1 98.0 109.2 243.3 49.5 105.7 112.1 200.5 414.7 152.4 130.8 351.0 135.3 408.0 73.0 255.0 282.1 139.8 116.9 393.7 269.3 125.0 220.8 292.1 225.7 88.4 138.0 290.7 237.4 346.6 67.1 200.1 173.5 131.9 8.8 51.3 10.4 32.6 69.6 34.1 481.0 16.5 23.9 99.2 488.1 42.6 39.3 4.8 60.3 77.1 313.2 4.6 95.2 257.2 248.9 253.4 292.4 247.8 296.3 250.0 267.7 260.2 266.7 282.5 281.3 76.1 112.2 213.4 69.5 83.8 34.7 77.5 114.6 36.5 247.7 43.6 32.3 98.2 108.7 169.0 68.0 183.5 89.9 41.3 705.9 25.4 250.2 28.5 86.1 63.4 57.6 91.3 19.4 47.8 354.0 35.6 90.8 85.1 41.7 23.4 88.6 53.6 29.5 65.4 127.9 54.3 290.4 97.6 58.0 27.5 57.9 64.3 38.2 72.9 29.0 35.1 508.9 36.0 116.6 32.7 245.1 410.7 51.6 81.2 220.1 364.3 65.5 201.7 185.1 26.3 44.8 189.0 108.0 64.6 34.2 34.2 75.9 19.4 149.5 205.2 381.4 TSPAN5 "NET-4, TM4SF9, Tspan-5" ENSG00000168785 "Tetraspanin 5" P62079 4 98470367-98658611 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 175.4;Excitatory neurons: 362.2;Inhibitory neurons: 248.3;Microglial cells: 195.8;Oligodendrocytes: 587.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 37 "B-cells: 3.0;NK-cells: 3.8;T-cells: 6.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 120.8;BJ hTERT+: 121.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (2.29e-1)" "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" "unprognostic (2.00e-3)" "unprognostic (2.65e-1)" "unprognostic (2.44e-3)" "unprognostic (1.41e-2)" "unprognostic (1.54e-2)" "unprognostic (9.27e-2)" "unprognostic (1.79e-1)" "unprognostic (3.30e-3)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.83e-5)" "prognostic unfavorable (8.56e-4)" "unprognostic (2.15e-1)" "unprognostic (3.23e-3)" "unprognostic (1.23e-1)" 2.7 1.2 32.5 3.8 37.2 10.4 15.4 62.0 42.7 13.5 21.6 6.4 1.5 19.9 29.2 12.9 7.2 5.0 3.2 41.4 33.5 5.1 0.6 4.3 6.7 32.8 30.8 46.4 0.9 4.0 5.1 7.9 34.5 5.3 3.8 28.1 10.8 8.7 3.8 20.0 3.0 16.4 32.4 9.9 8.9 12.6 33.7 8.5 18.5 3.2 9.2 8.8 9.7 47.4 27.8 10.8 11.0 0.7 41.2 120.8 3.7 111.9 121.4 39.4 48.3 9.6 14.6 0.0 1.1 40.2 21.6 7.0 9.6 52.6 87.7 34.3 5.2 16.9 1.5 0.4 42.5 9.5 0.9 70.1 1.6 72.5 89.1 60.5 64.5 11.3 6.6 29.1 95.3 0.7 29.1 0.1 7.2 23.8 49.2 8.8 10.5 4.2 3.5 8.1 77.5 14.8 2.0 35.4 0.2 3.7 1.2 1.4 66.4 82.7 37.4 29.8 39.9 20.0 31.8 0.0 32.4 22.5 28.8 0.0 0.0 0.0 3.3 0.0 3.6 1.3 4.7 4.7 0.1 3.0 2.4 1.6 0.1 3.8 0.0 0.0 6.0 1.1 32.5 37.2 62.0 42.7 41.4 33.5 32.8 30.8 34.5 32.4 33.7 47.4 4.6 22.4 9.1 129.3 5.6 22.0 24.8 9.1 10.8 63.9 30.9 26.0 2.3 0.0 9.3 29.5 27.1 1.0 17.2 1.4 5.9 2.3 69.6 8.5 45.9 19.7 80.9 175.4 362.2 7.1 0.9 26.0 10.2 15.1 2.5 11.6 8.2 0.9 2.3 111.0 248.3 4.6 20.3 3.4 15.4 91.4 46.0 7.1 28.4 195.8 0.3 21.5 39.1 94.5 587.2 25.3 0.5 17.0 9.3 45.9 0.4 0.6 3.7 41.9 6.6 9.7 13.1 10.1 4.1 33.0 57.7 2.9 31.4 79.7 3.8 44.8 TSR2 "DT1P1A10, RP1-112K5.2, WGG1" ENSG00000158526 "TSR2 ribosome maturation factor" Q969E8 X 54440404-54448032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030514 Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytosol" "HPA030514: AB_10603457" "unprognostic (1.05e-1)" "unprognostic (1.80e-2)" "unprognostic (1.77e-2)" "unprognostic (1.58e-2)" "unprognostic (2.64e-2)" "unprognostic (5.91e-2)" "unprognostic (7.15e-3)" "unprognostic (8.29e-2)" "unprognostic (4.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.94e-2)" "unprognostic (6.19e-2)" "prognostic favorable (1.21e-6)" "unprognostic (2.27e-1)" "unprognostic (1.13e-1)" "unprognostic (7.93e-3)" "unprognostic (1.80e-3)" 35.2 45.1 50.9 11.2 49.9 11.9 35.6 43.4 59.4 36.8 39.3 42.2 10.2 34.9 23.0 34.6 32.2 7.7 45.5 46.2 52.9 43.8 36.7 30.4 12.6 48.9 48.0 34.6 30.2 25.0 47.1 14.6 47.3 33.3 13.3 27.4 32.6 16.9 51.7 40.7 31.3 13.2 50.3 32.4 38.8 16.5 50.6 14.9 41.1 18.6 15.8 36.3 35.0 47.8 24.1 26.6 23.9 20.6 19.9 13.0 18.7 22.4 17.5 19.6 17.3 26.2 24.1 23.5 15.8 18.2 35.7 24.9 47.9 28.3 24.8 29.8 26.8 19.3 20.8 19.6 12.5 32.7 19.4 12.9 18.0 26.4 27.1 19.7 13.8 22.9 20.5 16.9 19.3 37.9 27.4 29.9 34.6 23.6 33.0 26.5 38.2 19.6 20.6 18.3 25.9 20.5 42.1 19.9 28.0 38.0 45.4 14.7 21.0 16.2 27.1 38.0 19.9 19.8 32.3 29.7 24.4 27.5 23.2 29.7 16.6 32.0 36.3 23.1 30.0 44.8 34.0 33.6 15.1 46.3 42.6 32.3 10.4 29.7 26.0 16.7 40.8 24.9 50.9 49.9 43.4 59.4 46.2 52.9 48.9 48.0 47.3 50.3 50.6 47.8 39.1 25.6 30.2 1.6 39.8 32.8 43.0 42.7 26.7 61.6 27.4 28.6 49.0 28.6 38.6 35.0 27.1 98.5 36.0 26.3 125.2 43.9 1.2 17.7 23.7 35.6 18.1 18.1 5.7 32.9 71.5 33.8 16.8 22.9 45.0 20.3 31.8 25.2 46.6 57.2 5.6 35.5 61.1 18.2 31.4 2.8 34.8 24.6 40.9 6.5 48.6 85.6 44.3 2.5 6.5 38.1 29.5 45.1 22.3 36.7 32.6 64.6 33.8 67.0 46.0 29.8 38.0 20.5 43.3 25.4 31.7 75.9 37.8 36.2 30.9 33.9 TSSK6 "CT72, FLJ24002, SSTK" ENSG00000178093 "Testis specific serine kinase 6" Q9BXA6 19 19512418-19515548 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "testis: 167.6" "Cell type enriched" "Detected in some" 5 "Late spermatids: 8709.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.4;CACO-2: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.12e-1)" "unprognostic (7.89e-2)" "unprognostic (7.26e-2)" "unprognostic (6.64e-2)" "unprognostic (3.39e-1)" "unprognostic (7.20e-5)" "unprognostic (3.38e-1)" "unprognostic (5.51e-3)" "unprognostic (5.17e-2)" "unprognostic (1.46e-1)" "unprognostic (3.98e-4)" "unprognostic (2.28e-2)" "unprognostic (5.34e-3)" "unprognostic (2.74e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-3)" "unprognostic (9.89e-2)" 0.6 0.7 0.4 0.0 0.6 0.1 0.7 0.5 0.5 0.4 0.1 0.7 0.5 0.8 0.0 0.7 0.6 0.0 0.3 0.3 0.2 0.9 1.2 0.4 0.3 0.7 0.6 0.5 1.0 0.0 0.7 0.0 0.7 0.9 0.0 0.0 0.6 0.0 0.3 1.6 1.0 0.0 0.6 1.2 0.9 167.6 0.5 0.1 0.9 0.0 0.1 0.6 0.6 1.0 0.0 0.6 0.0 0.0 0.0 0.1 3.4 0.1 0.2 0.0 0.1 1.7 0.0 0.7 0.1 0.0 0.0 0.4 0.1 0.6 0.0 0.5 0.0 0.4 0.4 0.0 0.4 0.4 0.7 0.3 0.1 0.2 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.3 0.7 0.3 0.0 0.0 0.6 0.0 0.5 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.5 0.2 0.9 0.2 0.8 0.6 0.0 0.7 0.4 0.9 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.1 0.8 0.4 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.6 0.5 0.5 0.3 0.2 0.7 0.6 0.7 0.6 0.5 1.0 0.2 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.3 0.1 1.7 1.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 1462.5 0.5 0.4 2.7 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.8 0.0 0.1 0.7 0.5 0.1 0.0 0.0 0.0 2.0 0.8 0.5 8709.8 47.8 2.2 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 57.2 0.1 0.1 0.5 0.2 0.3 0.0 19.7 1.1 0.3 57.7 25.7 0.0 0.1 0.1 0.2 0.0 0.1 0.1 TTC38 FLJ20699 ENSG00000075234 "Tetratricopeptide repeat domain 38" Q5R3I4 22 46267961-46294008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 233.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 134.2;NK-cells: 182.3;Proximal enterocytes: 144.5;Proximal tubular cells: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 90.5" "Group enriched" "Detected in all" 4 "granulocytes: 29.9;NK-cells: 38.0;T-cells: 90.5" "Cell line enhanced" "Detected in many" "Hep G2: 76.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029302, HPA075893" Approved Approved Cytosol NA NA 170000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA029302: AB_10601704, HPA075893: " "unprognostic (7.78e-2)" "unprognostic (5.85e-2)" "unprognostic (4.92e-3)" "prognostic favorable (3.21e-6)" "unprognostic (8.34e-2)" "unprognostic (6.38e-2)" "unprognostic (8.72e-2)" "unprognostic (3.62e-2)" "unprognostic (9.45e-2)" "unprognostic (7.22e-2)" "unprognostic (1.12e-1)" "unprognostic (5.66e-2)" "unprognostic (7.34e-3)" "unprognostic (9.02e-2)" "unprognostic (4.12e-1)" "unprognostic (4.97e-1)" "unprognostic (8.33e-2)" 24.7 23.6 9.5 10.2 11.6 46.9 25.7 10.3 10.7 16.8 12.8 42.1 79.4 13.8 6.4 12.5 17.2 15.5 23.2 9.7 11.0 64.4 233.6 15.6 10.7 13.3 12.3 26.0 35.5 7.6 13.2 7.8 11.9 23.6 31.9 4.7 27.0 7.3 20.6 12.2 80.9 10.3 10.3 22.8 29.1 6.8 12.2 2.5 15.2 12.3 5.9 16.9 13.5 11.3 12.0 13.2 16.4 34.5 15.2 13.1 15.7 17.2 11.5 18.7 14.6 21.8 8.5 0.1 10.8 17.9 7.4 10.8 16.8 13.9 6.8 27.0 36.9 15.6 28.4 76.0 21.0 9.0 59.8 22.6 7.3 8.5 9.7 12.9 15.9 0.2 11.9 19.4 12.2 12.1 0.3 28.2 12.5 22.6 13.1 0.0 8.0 8.0 12.6 13.8 2.9 22.8 23.7 16.3 13.3 7.5 26.1 18.0 18.5 13.0 14.1 10.3 11.0 14.7 9.2 1.7 8.8 13.7 13.8 29.9 11.9 22.5 90.5 11.4 9.7 2.3 8.5 41.0 10.8 1.7 3.5 36.9 7.6 38.0 8.7 4.3 4.5 42.5 9.5 11.6 10.3 10.7 9.7 11.0 13.3 12.3 11.9 10.3 12.2 11.3 9.2 0.0 7.5 13.7 6.5 3.3 5.9 4.3 3.4 2.6 10.2 6.7 9.2 38.6 4.3 9.2 6.2 10.4 69.1 69.0 23.5 10.4 0.3 7.4 9.6 8.9 20.9 10.5 0.3 10.2 9.3 7.5 11.7 6.9 17.2 13.3 9.7 134.2 13.4 5.0 1.8 37.8 4.1 14.9 4.3 0.9 7.5 9.6 5.4 9.4 12.8 9.3 182.3 5.5 5.6 9.7 51.6 13.9 16.2 8.6 144.5 149.6 5.3 5.4 6.6 7.4 5.9 1.8 3.7 5.3 8.2 6.4 29.2 22.7 51.7 4.6 TTC4 "CNS1, FLJ41930, MGC5097" ENSG00000243725 "Tetratricopeptide repeat domain 4" O95801 1 54715861-54742657 "Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041608, HPA042459" Approved Enhanced "Intermediate filaments,Cytoplasmic bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Intermediate filaments" "Cytoplasmic bodies" "HPA041608: AB_10794485, HPA042459: AB_10797496" "unprognostic (4.89e-2)" "unprognostic (1.81e-1)" "unprognostic (2.05e-2)" "unprognostic (8.62e-4)" "unprognostic (8.91e-2)" "unprognostic (1.34e-1)" "unprognostic (1.21e-5)" "unprognostic (1.39e-4)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (2.42e-3)" "unprognostic (7.12e-2)" "unprognostic (2.85e-1)" "unprognostic (7.79e-2)" "unprognostic (5.86e-2)" "unprognostic (1.76e-3)" 8.9 8.8 21.2 5.3 21.8 2.0 10.4 22.0 24.7 10.4 20.4 9.7 5.6 8.5 8.1 10.6 9.1 3.9 16.5 21.7 22.2 11.0 10.2 5.6 7.2 22.2 22.2 12.5 11.7 11.7 12.8 7.7 22.3 8.8 6.3 9.0 9.1 8.3 33.7 10.3 8.0 7.6 22.5 6.6 10.8 8.6 22.0 12.8 8.0 22.2 8.9 11.0 10.1 23.9 24.3 18.2 20.1 10.9 29.2 16.6 17.9 32.6 16.0 39.8 26.6 20.5 6.9 40.1 17.4 22.4 42.2 13.1 43.7 31.1 41.6 38.2 31.7 38.4 7.7 11.9 27.4 32.4 10.6 16.1 30.4 58.2 34.9 17.8 17.3 31.3 45.5 6.3 22.7 11.3 30.0 18.3 41.0 29.1 30.9 27.1 43.0 22.5 19.9 6.5 13.5 9.7 28.4 13.8 27.2 33.0 13.2 16.5 17.4 19.5 21.2 20.5 44.9 16.1 29.9 34.0 25.9 36.5 20.8 7.3 12.3 10.3 13.9 14.0 14.8 12.6 11.1 13.3 13.5 12.6 15.9 14.3 0.2 18.9 15.1 11.2 11.8 13.0 21.2 21.8 22.0 24.7 21.7 22.2 22.2 22.2 22.3 22.5 22.0 23.9 3.7 9.6 2.6 0.0 6.2 1.1 3.4 2.1 7.4 4.5 3.1 3.3 3.2 1.5 5.2 0.0 0.0 3.9 2.4 1.5 0.0 3.5 0.5 4.7 8.8 3.4 1.2 3.0 0.0 4.2 2.4 5.4 3.6 4.5 7.0 3.0 3.9 2.4 1.4 5.0 0.0 1.3 0.0 0.6 1.5 0.7 4.1 2.7 1.8 0.0 5.9 2.3 6.2 0.0 0.0 3.9 1.7 2.6 6.1 3.0 2.0 6.4 2.6 3.8 0.0 3.8 3.5 9.2 8.2 5.7 1.6 1.4 4.6 1.9 2.5 1.8 TULP4 "KIAA1397, TUSP" ENSG00000130338 "TUB like protein 4" Q9NRJ4 6 158232236-158511828 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 32.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 171.0;Oligodendrocytes: 544.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005445 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA005445: AB_1080421" "unprognostic (6.51e-3)" "unprognostic (1.83e-1)" "unprognostic (2.05e-1)" "unprognostic (1.39e-1)" "unprognostic (3.41e-1)" "unprognostic (9.77e-2)" "unprognostic (6.07e-2)" "unprognostic (1.55e-1)" "unprognostic (2.32e-1)" "unprognostic (4.79e-2)" "unprognostic (1.42e-2)" "unprognostic (3.04e-1)" "unprognostic (2.01e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-1)" "unprognostic (9.65e-2)" 2.4 2.5 27.1 2.1 32.7 1.1 3.1 15.0 16.1 2.8 0.0 2.5 4.0 3.0 2.8 3.5 2.1 2.2 2.6 15.2 13.1 3.1 2.3 2.7 3.1 16.1 23.9 2.5 2.7 5.0 4.6 2.6 10.8 2.4 2.0 7.0 3.1 2.4 6.3 6.0 4.3 2.4 14.8 2.9 3.0 4.0 19.3 3.2 4.6 3.6 3.0 2.4 3.0 27.1 2.7 5.7 4.1 9.1 7.2 4.5 8.6 2.6 3.7 2.4 2.9 8.4 1.7 7.4 2.5 5.3 7.0 4.7 4.9 6.4 4.4 4.8 2.7 3.7 4.2 8.7 5.2 3.4 3.9 3.5 7.3 4.0 8.3 8.7 6.2 7.0 5.8 11.3 6.8 4.1 3.5 3.9 2.8 3.2 2.6 7.4 9.8 4.7 4.0 4.3 7.9 9.8 7.5 11.1 8.0 3.9 6.5 4.5 10.0 6.2 7.4 9.2 10.1 7.7 10.1 6.2 5.9 2.6 7.8 0.3 1.4 0.0 1.8 1.5 2.4 1.8 2.1 2.4 0.9 1.9 1.5 1.7 0.1 1.3 2.1 3.2 2.9 1.6 27.1 32.7 15.0 16.1 15.2 13.1 16.1 23.9 10.8 14.8 19.3 27.1 27.0 3.2 25.4 62.7 25.8 21.4 16.4 12.3 16.5 51.2 31.3 22.5 52.8 12.8 20.6 25.8 171.0 29.4 25.9 16.5 15.6 18.0 5.3 46.5 51.2 25.7 20.4 7.8 157.3 15.7 8.9 20.0 13.7 51.6 5.1 17.7 16.8 15.2 12.9 158.2 153.4 13.3 8.2 17.9 10.7 8.4 28.3 15.4 16.0 76.8 13.0 16.1 14.4 137.2 544.9 22.5 15.3 41.8 24.7 20.8 53.2 26.0 18.8 79.8 13.1 33.9 26.8 21.8 33.5 19.6 39.2 18.9 21.1 52.4 17.3 23.6 TYMS "HsT422, TMS, TS, Tsase" ENSG00000176890 "Thymidylate synthetase" P04818 18 657653-673578 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.5;lymphoid tissue: 113.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 105.8;Erythroid cells: 189.3;Extravillous trophoblasts: 115.3;Plasma cells: 112.7;Spermatocytes: 180.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.1" "Group enriched" "Detected in many" 6 "NK-cells: 6.7;T-cells: 14.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002784, HPA074922" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB002784: , HPA074922: " "unprognostic (7.58e-2)" "unprognostic (2.06e-3)" "unprognostic (9.31e-2)" "unprognostic (2.34e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.10e-6)" "unprognostic (1.62e-3)" "unprognostic (1.68e-2)" "unprognostic (9.82e-2)" "unprognostic (1.07e-3)" "unprognostic (3.28e-2)" "unprognostic (1.23e-2)" "unprognostic (6.34e-2)" "unprognostic (1.66e-1)" "unprognostic (5.65e-3)" "unprognostic (2.47e-1)" 4.5 3.1 4.3 24.2 7.5 88.5 6.7 4.1 6.5 4.8 2.7 22.9 10.5 5.1 1.3 14.8 5.6 3.8 2.2 5.0 4.9 6.5 11.8 4.9 36.1 4.9 5.2 2.1 3.6 1.8 1.6 22.3 4.4 3.1 27.1 4.2 3.9 2.0 0.4 6.2 14.8 12.7 4.8 10.6 8.8 34.3 6.1 113.6 2.1 0.4 44.5 8.4 5.5 10.3 102.7 156.6 320.4 154.9 35.1 57.9 159.9 238.9 141.1 251.7 299.9 132.8 80.1 160.0 91.5 129.9 143.2 45.1 225.3 89.7 216.1 152.3 244.9 273.1 135.8 229.4 8.2 564.8 286.5 51.5 20.7 159.6 49.6 48.4 214.4 334.0 222.0 249.6 321.8 118.1 687.7 311.4 114.7 124.3 114.0 446.8 287.0 191.3 95.6 88.9 106.0 175.7 201.4 91.6 61.1 197.3 63.5 253.5 85.0 289.7 569.5 267.3 474.2 305.9 405.2 367.3 75.2 240.6 339.2 0.0 0.0 1.3 1.1 0.1 0.0 1.1 2.8 2.2 1.8 0.0 0.0 0.6 0.7 6.7 0.1 0.3 14.1 2.9 4.3 7.5 4.1 6.5 5.0 4.9 4.9 5.2 4.4 4.8 6.1 10.3 2.1 0.0 2.3 1.6 15.7 14.4 15.9 13.0 27.9 0.5 7.8 11.7 3.6 2.8 6.7 0.0 0.0 105.8 14.5 15.5 1.9 2.3 34.4 5.6 8.4 12.5 1.2 189.3 0.4 0.8 115.3 28.3 14.3 7.4 7.0 76.2 6.8 4.3 71.4 0.0 0.6 20.9 10.2 15.6 19.4 31.9 6.2 10.7 10.6 1.0 3.9 45.0 5.2 0.5 15.6 1.5 8.9 3.8 112.7 5.0 13.8 36.6 1.0 2.4 13.1 1.3 32.6 180.8 30.7 48.0 7.2 27.0 21.3 10.5 54.9 18.7 TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583589 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0;ovary: 49.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.4;Leydig cells: 44.4;Oligodendrocyte precursor cells: 29.1;Oligodendrocytes: 46.8;Peritubular cells: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 69.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved NA NA 17000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071245: AB_2686371" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" 21.5 3.5 18.2 1.4 30.3 0.8 5.2 17.7 27.1 2.1 0.0 2.3 1.6 4.6 3.5 13.1 11.5 2.5 2.2 27.7 10.7 11.3 0.8 3.3 1.3 20.9 22.6 49.7 9.8 0.9 0.9 5.7 18.6 2.6 0.9 2.6 1.9 6.1 0.9 13.8 2.4 4.4 14.4 5.5 3.2 18.8 15.7 0.4 1.1 1.8 3.7 2.1 4.1 32.0 10.3 6.7 20.7 22.7 18.9 12.8 69.2 14.6 9.3 14.2 13.1 37.7 3.4 0.4 18.3 11.9 19.9 23.7 23.3 3.6 6.5 5.8 15.5 3.2 20.2 18.1 13.3 5.2 0.4 4.1 7.3 10.9 3.6 5.8 10.6 9.8 19.1 4.3 7.9 9.8 2.4 1.0 47.7 16.0 6.7 31.9 18.6 3.8 1.2 19.7 24.6 7.0 13.7 21.6 16.3 29.8 17.8 6.0 8.4 28.0 12.2 21.0 22.5 1.7 3.5 3.1 17.2 33.8 17.2 1.1 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.3 0.2 0.2 1.5 0.3 0.1 0.3 0.1 0.1 18.2 30.3 17.7 27.1 27.7 10.7 20.9 22.6 18.6 14.4 15.7 32.0 3.4 3.2 1.1 17.6 0.9 6.8 8.5 0.4 0.6 2.7 2.2 2.2 2.9 2.8 0.7 3.7 6.2 2.9 1.1 1.3 0.0 3.9 3.6 1.1 13.0 5.4 1.8 0.0 42.4 3.6 10.2 10.5 8.6 1.9 0.0 7.6 9.7 0.4 1.2 0.0 4.6 0.9 0.0 1.9 1.3 5.1 44.4 0.9 8.8 1.0 0.1 8.3 1.0 29.1 46.8 4.6 0.1 47.0 0.3 6.4 1.2 1.2 0.5 4.0 0.0 3.9 4.3 4.0 6.5 4.2 10.9 18.9 0.7 5.8 2.3 5.7 UBAP2 "bA176F3.5, FLJ22435, KIAA1491" ENSG00000137073 "Ubiquitin associated protein 2" Q5T6F2 9 33921693-34048949 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021684 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA021684: AB_2211887" "unprognostic (2.71e-1)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (1.21e-1)" "unprognostic (4.64e-2)" "prognostic favorable (8.59e-4)" "unprognostic (1.75e-1)" "unprognostic (9.76e-3)" "prognostic favorable (1.95e-4)" "unprognostic (8.06e-2)" "unprognostic (2.39e-1)" "unprognostic (2.95e-1)" "unprognostic (8.77e-2)" 12.2 25.7 12.5 8.2 12.9 17.2 12.8 17.3 13.4 15.5 5.3 13.8 8.7 13.0 8.8 19.1 11.4 6.6 15.3 9.5 13.7 14.9 11.1 13.2 10.4 9.4 9.5 15.2 15.4 9.3 11.0 11.8 9.7 14.3 12.1 9.9 13.1 6.7 37.8 22.2 10.8 10.3 6.8 10.9 14.0 32.5 13.6 13.9 15.8 20.5 12.1 12.5 15.2 12.9 40.5 36.5 25.9 32.9 25.2 22.0 31.2 31.8 19.6 32.1 31.0 49.9 21.0 46.8 9.8 26.7 24.7 23.1 43.9 34.9 35.5 34.8 21.5 26.2 47.2 55.0 20.5 59.6 40.3 20.4 28.8 40.8 28.2 16.7 26.3 28.3 36.5 37.6 29.4 26.9 44.6 100.4 27.7 22.6 28.5 34.1 16.0 29.9 31.2 30.1 26.5 18.4 37.6 30.3 9.4 25.8 26.9 26.3 30.9 19.0 25.5 22.8 35.7 14.5 32.3 49.3 20.9 22.5 48.3 1.6 2.7 3.0 2.2 3.1 4.7 2.7 2.7 3.2 3.1 1.4 2.4 3.3 1.6 4.5 7.2 4.1 3.3 2.3 12.5 12.9 17.3 13.4 9.5 13.7 9.4 9.5 9.7 6.8 13.6 12.9 23.8 54.5 23.1 56.8 15.0 28.2 23.8 21.0 27.3 28.7 25.3 26.2 59.9 8.6 32.4 12.9 60.5 44.4 24.7 28.1 3.9 20.0 102.8 52.5 30.3 28.6 25.1 20.8 46.8 19.8 36.3 23.7 32.6 68.8 14.5 36.2 11.7 14.0 16.6 16.8 48.3 30.4 14.2 17.0 21.4 85.0 30.4 17.1 26.6 33.7 19.0 12.5 16.5 50.8 46.3 27.0 26.8 24.5 28.4 24.9 12.3 15.9 24.1 27.0 26.3 27.4 22.6 81.0 70.4 25.9 31.1 72.9 22.3 68.4 29.6 23.7 UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448859-6496723 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 26.1;heart muscle: 16.8;retina: 28.3;skeletal muscle: 54.5;tongue: 13.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.0;Cardiomyocytes: 27.6;Excitatory neurons: 47.8;Granulosa cells: 45.5;Horizontal cells: 45.4;Inhibitory neurons: 35.3;Rod photoreceptor cells: 63.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 29.7;PC-3: 24.6;SCLC-21H: 23.1;U-266/70: 54.4;U-266/84: 52.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favorable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" 1.2 1.4 14.3 0.4 14.6 0.0 1.1 16.5 26.1 2.1 1.8 5.3 0.3 0.8 1.0 0.4 0.7 0.4 16.8 17.9 11.4 3.4 1.2 0.1 0.1 12.0 7.9 2.6 0.6 0.1 3.2 0.0 11.6 3.5 0.3 28.3 0.8 5.5 54.5 1.5 1.4 0.7 5.6 0.2 2.9 0.7 10.1 0.3 1.2 13.9 0.2 0.3 1.3 17.7 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.7 0.0 5.3 0.0 0.0 0.3 0.0 24.6 0.1 0.0 11.5 0.0 0.0 23.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 54.4 52.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 14.6 16.5 26.1 17.9 11.4 12.0 7.9 11.6 5.6 10.1 17.7 0.2 0.0 0.0 5.5 0.3 1.3 0.5 0.5 0.0 30.0 0.4 1.0 27.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 5.9 0.0 0.0 0.2 0.4 1.0 5.4 0.0 47.8 0.2 0.0 3.6 1.1 0.1 0.0 45.5 0.0 1.0 0.1 45.4 35.3 0.0 0.0 0.3 0.3 0.3 4.1 0.1 0.0 2.8 0.0 9.4 0.0 12.1 5.4 0.1 0.0 6.8 1.8 0.9 0.0 0.2 0.0 63.6 0.0 3.2 1.4 0.1 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.0 UBTF "NOR-90, UBF, UBF1, UBF2" ENSG00000108312 "Upstream binding transcription factor" P17480 17 44205033-44221626 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004611, HPA006385" Supported Supported Enhanced "Nucleoli fibrillar center" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli fibrillar center" "CAB004611: AB_671403, HPA006385: AB_1080447" "unprognostic (1.37e-3)" "unprognostic (1.12e-3)" "unprognostic (2.54e-1)" "unprognostic (1.12e-2)" "unprognostic (3.15e-1)" "unprognostic (8.54e-3)" "unprognostic (1.35e-3)" "unprognostic (4.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-2)" "unprognostic (2.10e-1)" "unprognostic (1.96e-3)" "unprognostic (5.44e-2)" "unprognostic (9.01e-2)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" 34.8 36.5 36.2 44.8 33.7 54.9 35.4 38.2 37.1 50.6 30.1 49.4 33.6 50.8 27.5 41.8 41.9 32.5 38.8 35.5 32.7 38.1 36.1 32.3 67.6 34.0 34.5 41.6 41.4 38.2 33.8 29.2 32.2 41.6 28.2 23.1 37.7 40.8 63.7 47.4 42.5 36.3 31.6 49.8 34.7 20.8 34.9 73.6 46.4 36.6 51.7 45.1 41.8 35.0 69.1 104.3 77.3 93.2 49.6 56.5 72.3 70.6 46.7 70.1 52.0 50.7 54.8 250.0 69.3 65.3 51.9 63.6 99.1 59.2 57.9 145.3 109.5 100.5 73.8 83.7 32.5 192.1 85.7 56.9 52.2 44.6 65.6 67.2 58.9 108.8 117.4 75.9 58.9 113.7 188.3 75.0 73.7 46.6 81.6 184.0 104.3 112.0 40.4 54.5 119.5 90.3 70.4 62.2 54.2 47.9 89.9 120.8 75.5 109.9 133.1 65.1 95.0 66.6 61.7 151.1 64.8 86.0 100.1 9.6 5.7 6.1 15.5 6.3 16.7 11.7 10.8 16.2 6.7 14.1 12.2 13.1 9.7 15.7 11.6 12.7 10.0 11.3 36.2 33.7 38.2 37.1 35.5 32.7 34.0 34.5 32.2 31.6 34.9 35.0 41.4 41.7 42.1 14.7 57.5 20.5 19.6 17.9 57.5 88.8 31.0 29.6 44.5 35.8 32.2 38.6 79.2 30.9 60.3 41.7 35.2 27.2 2.3 39.3 57.7 42.7 47.3 61.2 8.5 40.8 40.7 38.9 23.9 48.1 31.7 43.1 32.5 26.5 25.9 26.9 8.2 32.5 12.2 18.4 13.3 3.6 36.7 27.4 23.2 8.4 38.1 33.9 54.6 3.5 10.6 28.1 30.7 50.8 42.2 17.4 26.7 25.4 26.5 57.6 52.6 48.5 45.9 5.3 44.0 52.1 24.3 32.7 53.1 40.2 32.8 11.8 UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "kidney: 1299.8;liver: 1612.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 150.6;Glandular and luminal cells: 234.7;Hepatocytes: 550.8;Proximal tubular cells: 1249.5" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 310.8" HPA045108 Uncertain NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA045108: AB_2679218" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favorable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favorable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favorable (5.38e-4)" 0.2 0.0 0.0 0.3 0.0 0.0 2.3 0.0 0.0 32.0 0.0 3.8 68.7 8.9 24.2 0.2 49.9 10.4 0.0 0.0 0.0 1299.8 1612.1 0.4 0.0 0.0 0.0 0.1 9.9 0.0 0.0 0.1 0.0 0.3 6.9 0.0 3.6 27.5 0.0 0.3 66.6 0.3 0.0 0.0 0.9 0.1 0.0 0.9 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.3 0.0 0.0 77.6 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 41.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.1 0.6 0.1 310.8 2.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 43.2 0.0 0.0 0.0 0.2 0.3 0.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.6 1.6 0.0 0.0 1.2 0.6 0.1 38.6 2.1 125.0 0.0 0.0 0.0 5.7 97.8 6.6 0.3 150.6 14.0 1.0 3.5 2.7 0.4 10.6 0.0 0.1 0.0 234.7 0.0 0.0 8.9 550.8 0.1 0.0 0.3 37.3 0.0 13.8 0.0 0.0 1.8 7.6 3.6 0.0 0.0 0.0 0.0 1.5 0.4 13.0 10.7 0.0 0.0 0.6 70.6 1249.5 0.5 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 6.3 0.1 5.9 2.3 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 27.0;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 49.7;Plasma cells: 21.0;Squamous epithelial cells: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Group enriched" "Detected in many" 4 "dendritic cells: 4.8;T-cells: 2.3" "Cell line enhanced" "Detected in all" "MOLT-4: 450.9;REH: 1004.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 1.0 0.9 2.1 9.6 2.7 27.0 1.7 2.1 2.3 1.6 1.8 2.9 3.7 1.0 0.1 6.5 0.4 0.8 0.5 2.0 2.2 0.6 0.9 1.3 15.8 2.8 2.8 0.3 0.6 0.2 0.2 2.1 2.7 0.6 2.6 0.4 1.5 0.2 1.2 3.4 3.9 1.9 1.9 3.7 3.3 5.2 3.5 67.2 0.3 0.3 10.3 1.6 2.5 4.6 111.3 78.7 116.6 83.4 3.3 13.3 18.5 88.3 42.0 89.9 86.8 94.6 54.9 62.7 21.1 39.4 32.7 54.1 81.2 47.7 63.0 102.7 92.2 54.3 74.3 102.4 1.3 135.1 78.9 6.5 3.5 48.9 12.6 14.1 27.2 97.2 79.3 70.5 54.5 86.7 450.9 82.5 52.5 40.0 84.3 1004.5 259.7 45.4 24.9 80.1 86.0 68.5 69.2 37.7 12.1 18.8 68.2 127.6 34.2 94.6 76.7 124.3 108.3 29.8 33.1 183.5 54.8 129.7 123.3 0.3 0.2 0.1 0.6 0.0 0.0 0.2 0.8 1.0 1.3 0.1 0.2 0.8 0.8 0.5 0.2 4.8 2.3 0.6 2.1 2.7 2.1 2.3 2.0 2.2 2.8 2.8 2.7 1.9 3.5 4.6 0.2 0.0 0.0 1.6 2.1 0.0 0.8 0.0 3.4 2.5 4.4 2.8 4.3 1.5 0.6 0.0 0.0 6.6 6.9 2.6 0.0 2.2 2.9 1.3 1.8 2.2 0.0 49.7 0.4 0.4 7.8 4.7 8.6 2.4 0.0 10.4 0.4 0.7 8.9 3.3 0.4 2.3 0.0 1.9 0.0 1.8 0.6 3.8 0.0 0.0 2.0 0.6 1.0 3.0 1.3 4.2 1.9 0.4 21.0 0.6 1.4 0.2 0.7 0.7 0.0 1.2 6.1 6.1 11.9 15.8 0.0 1.4 3.7 1.5 8.3 1.3 ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962130 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 352.3;Excitatory neurons: 108.6;Inhibitory neurons: 99.2;Late spermatids: 405.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" 2.7 3.1 1.6 2.9 2.1 8.5 2.5 0.4 1.7 8.5 16.9 1.6 1.2 6.6 4.5 1.5 9.0 1.9 8.6 2.3 2.5 3.9 2.1 3.5 3.0 6.9 7.6 2.1 2.0 8.0 2.9 2.7 3.9 2.2 1.7 6.0 1.7 2.4 0.4 2.1 2.0 3.5 5.6 2.0 2.4 23.4 2.5 3.0 4.9 0.4 2.7 1.9 3.7 2.1 8.3 2.9 2.8 3.8 1.1 1.7 4.8 2.7 2.7 3.2 3.0 1.0 2.3 9.5 1.6 6.3 3.5 4.1 3.7 2.1 2.9 1.5 1.0 2.1 5.7 3.3 4.1 6.5 1.8 1.6 2.3 16.1 3.2 4.4 2.2 6.4 2.1 7.5 2.3 6.4 8.1 4.9 3.4 2.1 3.4 1.7 9.1 4.5 7.2 7.6 1.6 10.3 3.1 1.3 2.8 1.8 3.1 2.0 6.6 2.0 2.4 14.2 2.5 4.5 9.0 3.9 11.5 6.3 2.5 3.7 3.7 4.0 5.0 4.3 4.1 3.7 5.3 4.5 3.3 4.7 4.0 5.7 6.6 1.8 2.3 3.3 7.7 3.0 1.6 2.1 0.4 1.7 2.3 2.5 6.9 7.6 3.9 5.6 2.5 2.1 6.4 9.6 6.9 84.9 11.2 2.0 3.0 4.0 5.2 5.6 5.7 4.6 14.8 4.3 5.1 3.7 54.2 3.1 9.9 2.0 0.0 3.4 352.3 45.3 27.4 6.0 1.8 2.1 108.6 2.4 4.1 8.7 10.2 7.5 1.3 49.6 1.8 6.6 7.3 11.8 99.2 1.2 2.0 3.1 4.0 405.2 6.5 6.9 0.0 80.6 5.9 10.4 3.1 49.8 62.0 3.0 0.7 4.1 5.1 0.9 1.1 5.9 47.3 26.7 6.6 4.4 10.5 38.9 9.6 3.3 3.7 4.2 10.8 3.6 1.9 1.2 UNC5C ENSG00000182168 "Unc-5 netrin receptor C" O95185 4 95162504-95549206 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 2078.8" "Cancer enriched" "Detected in many" 4 "thyroid cancer: 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 82.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.55e-1)" "unprognostic (2.72e-1)" "unprognostic (1.35e-2)" "unprognostic (8.45e-2)" "unprognostic (3.03e-1)" "unprognostic (3.20e-1)" "unprognostic (3.48e-1)" "unprognostic (3.40e-1)" "unprognostic (3.12e-1)" "unprognostic (1.11e-3)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (2.70e-5)" "unprognostic (1.25e-2)" "unprognostic (1.16e-1)" "unprognostic (1.86e-1)" "unprognostic (3.62e-4)" 1.9 9.0 8.9 1.0 17.2 0.0 1.3 7.0 17.4 1.8 0.0 2.9 1.4 2.4 1.7 0.6 1.9 2.0 3.1 6.6 15.4 1.1 1.0 2.5 0.5 18.1 8.7 2.8 0.3 0.1 1.2 1.8 21.4 3.3 3.4 6.4 6.3 3.9 0.1 0.2 1.9 2.0 8.0 4.2 2.1 2.6 16.4 1.9 11.9 0.4 0.3 2.6 1.6 40.5 0.0 0.5 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.2 4.2 0.0 0.2 0.0 1.1 0.2 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 82.9 0.0 0.0 0.2 4.8 0.3 12.3 0.0 0.1 1.2 0.0 7.9 0.0 0.0 0.0 0.1 9.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 17.2 7.0 17.4 6.6 15.4 18.1 8.7 21.4 8.0 16.4 40.5 0.7 0.0 0.0 105.4 0.0 0.1 0.1 0.1 0.0 1.9 0.7 1.5 1.7 0.0 0.2 1.8 0.0 0.5 0.0 2.6 0.0 0.0 0.7 0.5 3.4 0.7 1.2 0.0 326.1 0.0 0.1 4.6 0.0 1.2 0.0 20.2 0.4 0.0 1.8 0.0 448.3 0.5 0.0 0.8 0.0 0.8 21.1 0.4 1.8 57.1 0.0 1.3 0.0 308.1 2078.8 0.0 26.9 11.7 0.0 0.3 0.0 0.1 0.0 12.5 6.6 0.3 4.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 1.1 0.0 URI1 "C19orf2, FLJ10575, NNX3, PPP1R19, RMP, URI" ENSG00000105176 "URI1 prefoldin like chaperone" O94763 19 29923644-30016612 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Protein phosphatase inhibitor, Repressor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 499.7;Late spermatids: 514.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071709 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA071709: AB_2686434" "unprognostic (4.22e-2)" "unprognostic (2.75e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.96e-2)" "unprognostic (2.98e-1)" "unprognostic (1.40e-3)" "unprognostic (8.12e-2)" "unprognostic (1.26e-2)" "unprognostic (4.42e-3)" "unprognostic (1.57e-1)" "unprognostic (3.71e-1)" "unprognostic (1.33e-1)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (1.42e-1)" "unprognostic (4.47e-2)" 25.0 30.6 29.7 24.8 39.6 36.4 36.7 57.8 40.7 27.9 21.0 26.1 23.5 34.2 32.3 28.5 30.2 25.1 28.1 25.0 36.8 25.6 30.5 22.9 39.9 35.9 32.3 44.1 21.9 31.4 11.0 24.1 34.5 37.7 32.1 32.4 27.2 30.4 52.8 44.9 23.4 22.8 28.4 30.0 25.0 51.6 30.9 31.7 55.4 36.2 37.3 24.8 10.7 45.6 64.8 85.9 39.5 61.7 27.5 39.8 66.5 41.3 34.4 29.5 33.7 45.4 41.5 99.7 79.4 48.2 23.4 44.6 84.8 52.7 66.5 69.7 48.5 90.8 44.3 59.7 39.7 88.5 37.3 35.1 70.6 25.7 95.7 31.7 22.1 58.2 109.7 27.2 37.4 55.3 58.0 37.1 37.1 83.4 26.2 56.7 73.2 40.5 19.4 75.3 63.4 49.7 47.1 56.3 62.2 41.7 23.5 54.8 29.1 72.1 63.9 35.6 63.3 74.4 86.2 67.7 35.5 76.5 44.4 3.4 1.3 1.8 2.9 1.4 2.5 1.9 2.6 3.0 1.1 4.5 3.1 3.1 0.1 2.2 1.4 1.6 2.2 0.8 29.7 39.6 57.8 40.7 25.0 36.8 35.9 32.3 34.5 28.4 30.9 45.6 51.6 44.8 38.8 59.1 48.6 57.0 95.3 19.4 40.5 60.6 67.6 68.1 52.8 48.6 28.2 40.5 25.0 19.2 84.4 21.7 105.7 16.9 499.7 48.5 82.8 32.5 28.9 38.5 79.9 27.8 28.7 45.6 41.3 41.8 30.9 54.5 31.8 50.9 15.4 52.2 122.3 36.5 18.3 33.6 24.0 514.0 43.8 32.9 32.0 74.9 25.0 58.5 70.0 137.7 178.4 19.4 23.7 41.3 53.3 123.9 19.4 85.2 38.8 59.8 13.1 82.3 48.5 72.2 52.2 44.8 73.6 13.1 74.2 91.6 37.0 94.3 USP5 IsoT ENSG00000111667 "Ubiquitin specific peptidase 5" P45974 12 6852148-6866632 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006756 Uncertain Approved Nucleoplasm,Cytosol NA NA 1200000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA006756: AB_1080534" "unprognostic (2.19e-1)" "unprognostic (5.83e-2)" "unprognostic (2.48e-1)" "unprognostic (2.57e-1)" "unprognostic (7.60e-2)" "unprognostic (2.21e-2)" "unprognostic (4.02e-2)" "unprognostic (3.93e-2)" "unprognostic (2.57e-1)" "unprognostic (4.71e-2)" "unprognostic (8.90e-3)" "unprognostic (4.69e-2)" "unprognostic (1.17e-2)" "unprognostic (2.65e-2)" "unprognostic (3.56e-1)" "unprognostic (3.23e-1)" "unprognostic (2.02e-3)" 27.1 37.9 23.7 26.7 26.1 22.8 19.5 15.5 38.0 24.1 2.4 31.3 25.3 31.5 17.4 38.2 25.9 18.5 33.0 25.3 33.6 20.1 23.1 20.5 29.2 31.0 31.3 19.4 17.8 41.4 27.8 25.4 38.8 26.5 22.2 15.7 20.0 29.6 66.7 48.1 26.1 35.5 15.0 21.2 22.9 40.9 28.9 36.5 26.7 42.5 29.4 29.8 24.2 29.0 88.1 135.7 88.4 100.4 59.0 53.9 113.4 93.0 70.9 109.2 78.8 129.4 84.9 105.7 47.6 98.5 86.5 75.2 98.6 92.7 69.5 198.6 84.0 97.1 105.5 71.0 45.8 88.5 97.2 55.6 52.9 94.8 64.9 72.9 94.8 41.7 85.4 40.9 91.1 97.4 132.9 44.4 172.8 89.3 56.5 103.4 115.5 73.5 62.9 84.5 48.5 97.4 63.5 96.3 41.1 110.6 38.3 72.4 92.4 91.5 109.1 70.4 117.6 49.0 124.5 163.8 102.1 55.3 91.3 5.4 19.3 8.3 24.3 25.1 23.1 15.0 21.7 20.8 28.4 13.9 20.1 20.9 1.3 17.6 24.4 20.5 19.9 27.7 23.7 26.1 15.5 38.0 25.3 33.6 31.0 31.3 38.8 15.0 28.9 29.0 11.3 9.6 13.1 7.5 14.0 11.6 11.4 18.0 8.6 18.7 13.1 10.8 9.5 17.2 11.5 22.0 60.5 45.9 14.8 21.5 11.7 28.1 14.7 10.6 14.7 15.3 16.7 19.4 11.5 20.5 30.7 16.6 10.2 13.7 14.7 29.6 11.4 22.2 28.4 40.4 11.9 19.3 14.2 13.0 7.4 19.2 23.0 10.9 16.0 9.4 32.4 16.0 13.4 6.0 11.9 20.2 17.4 33.8 14.1 10.3 22.5 18.5 7.9 16.2 32.9 13.3 17.2 51.7 25.6 17.6 15.5 52.8 15.4 27.6 27.5 7.9 VANGL1 STB2 ENSG00000173218 "VANGL planar cell polarity protein 1" Q8TAA9 1 115641970-115698224 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 6.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.3;NK-cells: 6.2;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025235, CAB076375" Approved Approved "Plasma membrane" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB076375: AB_2665604, HPA025235: AB_1858718" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "prognostic favorable (7.53e-4)" "unprognostic (9.94e-2)" "unprognostic (1.71e-2)" "unprognostic (5.18e-2)" "unprognostic (2.18e-3)" "unprognostic (5.11e-3)" "unprognostic (2.11e-1)" "unprognostic (6.43e-3)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.88e-2)" "unprognostic (1.74e-2)" "unprognostic (7.71e-3)" "unprognostic (1.21e-1)" "unprognostic (4.50e-3)" "unprognostic (9.06e-3)" 4.9 3.9 2.1 3.8 1.2 2.5 3.2 0.8 1.1 9.1 3.0 6.8 3.8 5.5 4.9 10.4 12.0 3.8 5.4 1.3 1.3 5.3 3.0 4.1 2.1 1.2 3.0 4.4 5.0 5.2 0.5 3.6 1.7 4.4 6.4 1.6 6.4 4.5 0.9 6.8 3.9 7.3 1.2 2.2 5.5 5.0 6.5 7.3 7.6 2.4 2.5 6.4 4.4 1.0 49.6 20.7 6.6 8.9 24.1 21.5 13.1 18.8 13.5 24.1 19.1 12.0 24.1 0.0 31.5 21.9 22.7 60.9 11.2 33.3 15.8 57.9 13.7 27.4 18.4 9.8 8.8 8.2 11.4 11.4 23.1 17.2 18.2 12.8 24.1 45.9 16.8 14.8 24.5 65.7 41.0 3.4 16.7 28.8 19.5 0.1 19.1 14.3 11.0 32.8 5.9 8.0 33.9 22.2 15.4 12.4 11.3 8.8 26.2 16.5 25.7 36.3 34.6 2.1 2.3 0.2 22.3 14.3 41.1 0.0 0.5 0.0 1.9 0.3 0.5 0.2 1.2 1.9 2.3 0.0 0.4 2.0 0.0 6.2 0.5 2.0 3.0 1.0 2.1 1.2 0.8 1.1 1.3 1.3 1.2 3.0 1.7 1.2 6.5 1.0 9.2 3.2 3.2 5.5 0.5 7.4 7.4 16.8 11.4 5.2 4.6 4.6 7.9 2.8 9.6 9.2 39.6 5.0 3.4 11.2 0.0 15.7 6.1 25.1 7.7 10.5 6.7 13.2 0.9 13.8 7.3 10.1 8.2 17.0 0.0 5.1 28.9 2.5 4.3 0.0 0.7 8.6 10.2 1.9 1.4 3.0 5.9 2.9 0.0 4.7 11.1 4.7 9.2 2.0 0.1 20.8 6.1 8.2 1.8 8.3 2.6 5.6 12.8 0.9 6.6 4.3 8.5 5.5 7.0 20.0 6.5 0.4 3.1 3.2 10.3 6.5 VASN SLITL2 ENSG00000168140 Vasorin Q6EMK4 16 4371848-4383538 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 58.7;Fibroblasts: 104.2;Leydig cells: 50.1;Peritubular cells: 60.9;Sertoli cells: 98.6;Smooth muscle cells: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 21.8;MCF7: 18.4;U-2197: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011246, HPA016992" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted - unknown location" NA Yes 2000000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "Nucleoplasm, Nucleoli" "HPA011246: AB_1858720, HPA016992: AB_2732418" "unprognostic (2.20e-1)" "unprognostic (2.75e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.35e-3)" "unprognostic (8.91e-3)" "unprognostic (3.15e-3)" "unprognostic (5.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.82e-3)" "unprognostic (4.23e-2)" "unprognostic (4.95e-3)" "unprognostic (5.27e-2)" 55.7 15.5 1.5 5.8 2.3 2.7 31.5 0.8 2.3 48.1 3.0 12.1 3.4 30.3 0.0 34.1 24.6 7.3 30.5 1.1 0.5 56.1 31.8 44.9 2.8 6.3 5.5 40.0 10.3 0.0 12.8 10.4 1.7 17.9 0.0 0.3 15.9 0.0 6.9 38.8 11.2 0.0 1.6 13.0 13.4 16.8 4.6 0.0 26.8 0.0 0.0 26.5 38.9 2.7 4.2 0.0 0.6 0.5 0.2 0.2 12.6 21.8 0.1 0.0 0.0 1.9 5.5 0.0 4.5 0.3 2.6 0.3 0.0 0.0 0.0 13.7 2.2 0.9 15.9 14.9 0.6 0.0 0.4 7.9 0.0 0.3 0.0 3.1 0.0 0.1 3.1 0.8 0.0 18.4 1.0 5.3 2.2 0.4 2.4 1.0 0.0 0.0 0.0 0.1 1.4 9.3 6.5 13.5 0.6 2.2 6.8 2.5 0.0 17.5 12.5 78.4 4.6 0.0 0.0 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 0.8 2.3 1.1 0.5 6.3 5.5 1.7 1.6 4.6 2.7 10.0 6.4 13.1 5.5 1.4 9.6 7.8 4.2 9.1 0.5 21.9 10.9 16.2 32.9 6.4 23.9 0.0 5.4 2.8 1.5 7.9 13.1 1.1 12.1 58.7 4.6 0.0 0.0 1.1 2.9 7.2 104.2 16.8 20.5 3.8 4.6 2.9 15.3 3.4 0.0 0.9 2.0 2.0 0.6 21.7 2.8 50.1 2.0 14.2 2.8 0.0 18.3 0.0 0.5 0.3 28.3 1.2 60.9 0.8 6.4 0.2 12.3 2.7 0.7 98.6 12.6 80.9 0.8 4.1 3.7 7.5 10.0 3.5 2.3 0.8 4.9 VAV3 ENSG00000134215 "Vav guanine nucleotide exchange factor 3" Q9UKW4 1 107571161-107965180 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 83.9" "Cell type enhanced" "Detected in many" "Astrocytes: 263.5;Basal squamous epithelial cells: 163.9;Syncytiotrophoblasts: 246.0" "Cancer enhanced" "Detected in all" "breast cancer: 28.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 52.8;RH-30: 61.7;RPTEC TERT1: 86.2;T-47d: 107.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002012 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB002012: " "unprognostic (4.80e-3)" "unprognostic (7.99e-3)" "unprognostic (5.31e-3)" "unprognostic (3.78e-3)" "unprognostic (1.15e-1)" "unprognostic (1.67e-3)" "unprognostic (6.84e-2)" "unprognostic (2.34e-2)" "unprognostic (3.39e-2)" "unprognostic (1.88e-2)" "unprognostic (2.25e-1)" "unprognostic (2.34e-1)" "prognostic favorable (4.60e-8)" "unprognostic (1.89e-1)" "unprognostic (2.21e-1)" "unprognostic (7.47e-2)" "unprognostic (1.23e-2)" 3.1 1.7 4.1 10.8 4.4 19.3 34.1 5.9 7.1 6.9 15.4 41.2 9.3 4.5 4.0 34.9 3.7 2.6 1.5 2.2 3.5 83.9 2.4 4.1 10.4 4.2 7.1 0.5 17.4 1.5 1.4 34.3 4.3 4.3 50.9 7.4 7.3 11.5 0.9 49.0 15.2 3.6 1.5 11.2 7.2 5.1 9.2 8.8 9.9 1.2 16.6 12.7 16.1 3.0 0.0 12.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 3.5 16.9 0.6 0.2 0.0 0.0 4.5 17.4 5.8 10.2 0.0 16.3 6.5 0.0 36.6 0.0 1.1 0.0 0.0 8.5 0.0 13.3 0.2 5.7 34.2 4.2 5.0 0.2 1.2 52.8 61.7 0.4 86.2 29.5 2.8 2.6 16.4 7.2 0.3 1.5 107.2 29.7 1.2 0.6 0.0 0.1 0.6 8.0 3.3 0.5 13.0 26.1 1.2 4.7 0.6 0.7 2.1 0.5 1.1 1.7 0.6 1.0 2.6 2.0 0.1 1.4 1.7 2.1 0.2 1.6 2.6 0.7 4.1 4.4 5.9 7.1 2.2 3.5 4.2 7.1 4.3 1.5 9.2 3.0 7.3 0.0 1.7 263.5 37.0 11.7 10.3 13.3 163.9 15.0 48.5 21.5 2.4 5.7 17.8 51.5 2.1 108.8 91.0 87.3 117.4 7.9 55.7 11.2 1.1 9.6 21.1 11.3 38.2 0.0 25.6 3.1 2.6 5.8 7.6 0.0 10.0 0.2 23.6 0.0 77.7 29.1 4.1 15.7 10.6 40.1 0.3 22.1 3.6 23.4 13.3 3.8 69.0 36.2 2.4 0.1 47.2 0.4 32.7 2.1 25.2 79.6 12.3 28.4 6.6 51.1 1.6 1.3 3.0 108.7 21.0 246.0 30.3 8.8 45.9 4.7 VAX2 DRES93 ENSG00000116035 "Ventral anterior homeobox 2" Q9UIW0 2 70900576-70965373 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.4;retina: 11.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.5;Cone photoreceptor cells: 16.7;Horizontal cells: 11.8;Muller glia cells: 7.6;Rod photoreceptor cells: 19.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 4.7;MCF7: 5.6;RH-30: 4.6;SCLC-21H: 4.6;SH-SY5Y: 5.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 3.2" HPA009708 Approved "Nuclear speckles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear speckles" "HPA009708: AB_2668261" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.96e-2)" "unprognostic (3.16e-2)" "unprognostic (1.63e-2)" "unprognostic (2.17e-1)" "unprognostic (3.52e-2)" "unprognostic (7.23e-3)" "unprognostic (2.42e-1)" "unprognostic (1.98e-1)" "unprognostic (3.81e-1)" "unprognostic (2.16e-1)" "unprognostic (7.74e-3)" "unprognostic (6.63e-3)" "unprognostic (4.65e-1)" "unprognostic (6.67e-3)" "unprognostic (2.18e-2)" 1.5 0.4 1.8 0.1 1.0 0.0 1.1 5.4 1.6 0.9 0.6 0.6 0.0 1.0 0.0 0.4 0.7 0.0 0.6 1.9 2.6 0.4 0.0 0.5 0.0 0.9 1.0 0.7 1.2 0.2 0.9 0.2 1.0 0.7 0.0 11.1 0.8 0.0 0.5 1.2 0.3 0.3 0.7 0.0 0.2 0.2 1.6 0.0 0.2 0.1 0.0 0.5 0.4 1.0 1.5 3.6 0.8 4.7 1.2 0.7 2.6 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.5 0.2 1.8 0.0 0.1 0.0 3.0 0.0 0.0 2.1 0.6 0.0 0.0 1.2 0.0 0.2 0.0 1.3 0.4 0.2 0.0 0.0 1.8 5.6 0.0 0.0 2.0 0.0 0.0 0.0 4.6 0.0 1.5 1.2 4.6 5.6 3.7 0.0 2.1 0.1 2.1 0.2 0.9 2.2 0.5 1.1 0.9 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.0 5.4 1.6 1.9 2.6 0.9 1.0 1.0 0.7 1.6 1.0 3.2 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 9.5 1.4 1.4 0.1 0.0 0.1 0.0 16.7 0.1 0.1 0.2 1.9 1.2 0.1 0.0 0.1 1.5 0.0 0.0 0.6 0.6 0.4 1.4 0.0 0.0 0.0 0.0 1.1 0.1 0.0 11.8 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.8 0.0 4.2 7.6 0.0 2.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 19.5 0.0 0.8 0.8 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.1 0.0 VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 22.0;Leydig cells: 13.7;Microglial cells: 36.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 146.5;HBF TERT88: 114.4;hTEC/SVTERT24-B: 116.5;LHCN-M2: 129.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 25.0 6.9 2.6 4.2 2.5 0.2 16.7 2.7 2.8 9.7 2.1 4.7 2.4 7.3 1.8 4.0 8.5 6.8 12.7 2.4 2.4 6.7 4.2 16.8 8.0 3.1 2.8 5.9 1.8 2.7 1.5 19.3 2.9 5.1 3.3 1.2 7.4 5.0 3.1 5.1 6.8 6.6 2.6 3.9 3.2 1.4 3.7 1.1 27.7 4.1 3.4 10.3 7.6 2.5 5.9 2.8 1.8 0.0 25.5 25.3 0.0 146.5 87.3 79.2 62.5 0.0 0.7 0.0 0.0 82.7 33.1 4.4 1.3 54.8 114.4 0.1 2.8 0.0 3.8 0.0 13.9 0.0 0.0 27.0 2.5 116.5 80.5 79.3 49.7 0.0 0.0 0.0 129.9 2.1 0.0 0.0 1.3 0.0 47.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 2.3 3.3 0.1 0.7 0.7 0.2 24.2 83.6 9.2 20.8 42.1 0.2 0.0 0.0 34.9 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 2.5 2.7 2.8 2.4 2.4 3.1 2.8 2.9 2.6 3.7 2.5 39.3 3.2 0.0 10.1 0.1 2.4 1.3 3.2 0.0 1.0 3.2 1.7 1.5 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 3.1 8.3 10.9 22.0 0.0 0.0 2.0 0.0 0.0 9.1 0.0 11.0 0.0 8.5 10.0 0.0 0.3 1.7 2.0 0.0 4.1 0.3 2.2 1.2 13.7 0.4 3.6 36.5 0.0 3.4 0.0 1.5 0.6 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.2 0.0 1.9 11.7 0.2 2.0 0.3 2.0 0.0 0.2 1.9 0.0 3.6 VPS45 "h-vps45, H1, VPS45A, VPS45B" ENSG00000136631 "Vacuolar protein sorting 45 homolog" Q9NRW7 1 150067279-150145329 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 202.8;Late spermatids: 267.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027425, HPA027441" Uncertain Approved Microtubules NA NA "Cluster 44: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" Microtubules "HPA027425: AB_10599415, HPA027441: AB_10602284" "unprognostic (1.57e-1)" "unprognostic (2.75e-1)" "unprognostic (2.03e-1)" "unprognostic (5.51e-2)" "unprognostic (1.56e-2)" "unprognostic (8.36e-3)" "prognostic unfavorable (6.57e-6)" "unprognostic (4.76e-2)" "unprognostic (2.94e-2)" "unprognostic (2.65e-3)" "unprognostic (2.52e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.49e-2)" "unprognostic (1.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.32e-2)" 19.1 26.8 32.3 12.0 34.6 6.6 17.8 40.2 43.0 20.1 27.7 22.0 12.6 18.7 22.5 16.7 16.1 13.7 38.6 34.0 33.2 21.1 12.5 15.4 13.5 30.6 31.4 14.0 11.1 26.4 19.1 17.3 31.5 18.8 17.2 29.2 14.3 20.1 19.3 16.5 15.3 25.2 31.5 16.2 17.4 11.0 32.9 17.0 19.8 16.6 15.3 18.5 15.9 32.8 31.5 24.3 40.9 27.0 37.1 29.4 19.0 44.7 23.7 45.3 37.4 17.7 26.1 19.3 26.5 37.0 19.9 26.0 42.4 27.0 49.0 38.7 31.1 24.6 33.5 16.8 24.7 17.6 30.2 25.8 24.8 43.5 22.8 29.7 37.1 38.6 34.4 28.3 40.0 53.5 34.7 17.5 28.4 28.7 38.4 23.7 41.9 27.4 31.2 30.0 28.5 59.7 34.9 29.8 46.9 46.2 48.9 45.6 32.6 20.8 25.1 18.7 31.3 21.3 49.4 18.9 30.9 24.4 30.2 23.6 26.6 4.7 16.0 28.0 15.0 15.6 13.6 15.1 25.9 12.8 13.2 13.9 2.5 14.1 19.9 14.6 16.8 18.4 32.3 34.6 40.2 43.0 34.0 33.2 30.6 31.4 31.5 31.5 32.9 32.8 9.4 12.8 14.0 85.8 11.9 7.4 8.2 12.7 13.1 20.9 11.0 10.2 44.0 8.6 11.0 16.5 18.8 20.9 12.5 8.3 7.9 12.3 202.8 9.7 14.2 10.4 7.8 4.6 79.4 7.2 9.5 14.7 12.8 10.1 6.3 24.6 12.1 7.2 19.0 30.3 90.2 8.1 14.2 18.0 8.6 267.9 21.5 13.6 10.6 45.9 19.7 17.9 6.2 92.5 59.5 11.4 11.6 14.7 8.4 6.4 13.6 9.2 11.5 23.8 32.9 7.3 17.1 18.1 15.1 11.6 7.7 14.8 11.2 21.2 9.7 7.9 VPS51 "ANG2, ANG3, C11orf2, C11orf3, FFR" ENSG00000149823 "VPS51 subunit of GARP complex" Q9UID3 11 65089324-65111862 "Disease related genes, Predicted intracellular proteins" "Lipid transport, Protein transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039650, HPA061447" Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 50: Non-specific - Ribosome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" Nucleoli "HPA039650: AB_10673147, HPA061447: AB_2684521" "unprognostic (2.36e-2)" "unprognostic (7.58e-2)" "unprognostic (8.35e-2)" "unprognostic (1.56e-1)" "unprognostic (2.11e-2)" "unprognostic (1.64e-1)" "unprognostic (9.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "prognostic favorable (2.41e-9)" "unprognostic (7.77e-3)" "unprognostic (4.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.18e-1)" 48.5 37.8 19.0 34.9 23.1 60.9 46.6 22.0 30.7 45.6 20.4 55.4 52.9 54.4 7.3 42.5 46.1 20.3 45.3 22.5 15.5 33.7 36.2 34.2 48.6 18.5 18.6 83.8 120.3 37.4 28.6 22.2 20.2 38.1 25.1 20.3 65.5 27.7 84.2 71.2 49.7 22.7 14.3 40.9 70.3 28.4 17.2 46.7 39.7 42.9 32.5 45.2 38.1 21.5 71.8 74.5 35.7 44.4 15.5 38.5 72.1 27.5 53.2 52.6 38.8 55.2 88.7 118.0 76.1 51.4 27.3 60.0 37.9 59.3 19.2 69.6 62.1 72.5 72.6 55.1 51.3 77.1 65.0 66.8 39.9 39.0 32.1 41.6 58.4 55.0 73.6 82.9 21.7 95.1 105.8 83.0 59.8 30.7 61.5 67.5 17.5 150.7 36.2 76.2 61.5 87.8 20.7 110.9 71.8 21.0 93.7 39.1 48.1 35.2 32.0 45.4 39.7 115.7 92.2 68.9 39.9 28.0 26.3 10.6 15.0 15.4 17.9 15.8 21.2 22.4 25.2 27.1 22.1 21.2 23.3 20.7 8.0 30.6 16.0 19.1 17.7 18.3 19.0 23.1 22.0 30.7 22.5 15.5 18.5 18.6 20.2 14.3 17.2 21.5 49.8 19.2 47.7 18.9 77.3 49.1 66.3 46.0 58.6 64.7 76.5 67.8 5.8 44.3 27.8 31.3 29.2 78.4 73.7 156.5 62.6 49.2 77.5 25.6 35.0 46.5 95.8 50.5 21.8 120.5 79.4 38.8 45.9 34.4 37.5 47.3 55.3 52.5 45.5 67.3 24.1 110.0 32.6 54.0 30.6 222.4 53.4 36.1 49.8 15.9 71.3 65.9 89.6 21.6 28.0 51.2 144.4 54.5 66.4 45.1 158.7 75.9 16.1 52.5 26.3 49.3 44.4 40.3 31.4 52.3 54.8 115.3 64.0 61.5 170.5 51.0 VSNL1 "HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1" ENSG00000163032 "Visinin like 1" P62760 2 17539126-17657018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 663.3" "Group enriched" "Detected in many" 4 "Excitatory neurons: 442.7;Inhibitory neurons: 243.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 663.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 125.9;Hep G2: 124.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053808: AB_2682270" "unprognostic (1.04e-1)" "unprognostic (7.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (6.90e-4)" "unprognostic (4.90e-2)" "unprognostic (5.48e-2)" "unprognostic (2.81e-2)" "unprognostic (4.66e-2)" "unprognostic (2.99e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-1)" "unprognostic (5.14e-4)" "unprognostic (3.26e-2)" "unprognostic (1.23e-1)" "unprognostic (6.19e-3)" "unprognostic (1.51e-2)" 0.8 27.5 100.4 1.4 143.0 0.1 6.2 12.9 663.3 13.5 0.0 4.6 0.2 1.1 0.0 47.9 2.0 0.2 39.7 105.8 12.3 1.9 20.8 2.9 0.1 21.6 0.0 3.6 1.2 0.2 2.7 5.4 19.7 3.9 5.4 18.6 9.7 0.8 1.3 13.8 0.3 1.1 0.0 0.3 1.4 0.8 4.3 1.1 0.8 2.9 7.3 1.5 26.3 188.8 0.7 0.1 1.4 21.2 2.4 3.0 0.1 0.0 0.0 0.0 0.6 0.3 13.6 0.0 0.0 0.0 0.0 125.9 0.8 4.0 0.0 0.0 0.5 0.0 0.1 124.4 0.0 0.0 0.3 0.9 6.0 0.0 2.9 0.1 0.0 0.0 0.1 0.6 1.6 0.0 0.0 0.1 21.0 6.7 0.0 0.1 0.1 0.0 0.0 0.4 9.3 8.5 0.0 0.0 0.0 4.9 0.0 0.1 0.0 4.2 0.0 0.0 2.4 0.1 0.0 0.0 3.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 143.0 12.9 663.3 105.8 12.3 21.6 0.0 19.7 0.0 4.3 188.8 0.1 0.0 0.5 41.1 0.0 18.2 29.8 54.3 59.2 8.8 4.9 19.7 30.8 4.3 18.0 0.0 0.0 0.3 0.1 2.2 1.9 0.1 5.1 0.0 0.1 1.1 1.2 0.0 442.7 0.2 0.2 5.9 0.0 0.1 0.0 0.1 0.0 17.8 0.6 3.3 243.2 7.1 18.3 0.3 0.8 6.5 0.6 0.5 3.6 54.4 0.6 3.7 0.0 36.7 42.9 0.2 1.0 0.0 0.0 15.0 0.0 4.0 0.8 14.7 0.0 0.2 1.3 1.7 0.9 85.5 20.2 0.4 0.8 1.8 5.6 14.2 WAPL "FOE, KIAA0261, WAPAL" ENSG00000062650 "WAPL cohesin release factor" Q7Z5K2 10 86435256-86521792 "Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037874, HPA037875, HPA066141" Enhanced Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA037874: AB_10697086, HPA037875: AB_10672396, HPA066141: " "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (3.03e-2)" "unprognostic (2.91e-2)" "unprognostic (6.63e-2)" "unprognostic (3.51e-1)" "unprognostic (3.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.25e-1)" "unprognostic (5.78e-2)" "unprognostic (5.56e-2)" "unprognostic (7.61e-2)" "unprognostic (1.14e-1)" "unprognostic (1.88e-1)" "unprognostic (4.56e-1)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" 15.4 13.2 8.4 19.6 9.9 27.1 16.6 11.9 9.2 12.8 7.8 15.4 15.2 14.8 8.7 15.9 11.7 13.1 10.3 7.5 8.3 16.8 22.6 16.5 25.0 8.2 8.5 13.7 14.4 16.9 4.9 18.4 8.3 13.0 15.2 36.0 11.2 11.7 20.9 17.9 16.0 14.8 8.9 19.0 16.5 35.1 9.0 33.7 17.9 22.5 27.7 17.9 9.2 10.4 42.6 19.6 33.5 44.4 26.1 27.6 29.6 36.4 44.2 30.3 32.4 42.9 36.6 64.3 24.1 32.5 26.7 39.1 38.3 31.3 46.3 42.1 25.3 38.9 30.9 47.4 29.7 79.8 43.1 21.9 35.7 38.9 64.9 34.5 34.6 36.8 41.7 37.6 35.2 36.3 49.9 29.6 29.9 26.4 19.5 35.2 27.1 25.6 26.3 37.2 13.1 25.2 32.3 21.4 40.9 33.2 47.1 41.9 33.5 29.1 34.4 25.8 48.6 36.8 54.9 66.9 26.7 55.8 20.9 15.0 3.5 7.7 3.4 4.1 4.9 3.9 4.5 4.7 4.8 4.0 5.1 4.0 5.5 3.2 7.4 3.6 6.1 2.4 8.4 9.9 11.9 9.2 7.5 8.3 8.2 8.5 8.3 8.9 9.0 10.4 38.3 83.3 54.8 0.0 48.3 0.0 57.4 0.0 35.3 49.1 41.3 27.9 0.0 20.0 21.1 16.5 20.9 42.8 62.4 17.4 21.5 60.8 86.8 36.7 44.4 33.9 18.2 94.1 0.0 52.5 28.3 30.0 37.8 52.2 25.2 40.3 32.5 47.6 40.4 55.5 0.0 21.5 0.0 56.5 0.0 42.0 32.0 58.3 0.0 0.0 81.0 48.7 55.6 0.0 0.0 52.1 27.5 32.4 50.5 56.6 25.0 35.5 13.8 113.4 65.7 70.3 33.6 153.4 90.2 48.4 0.0 76.1 51.4 35.2 24.8 74.1 WDHD1 "AND-1, CHTF4, CTF4" ENSG00000198554 "WD repeat and HMG-box DNA binding protein 1" O75717 14 54938949-55027105 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 15.5;Spermatocytes: 15.0;Spermatogonia: 19.3" "Cancer enhanced" "Detected in all" "testis cancer: 23.5" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000632, HPA001122" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA000632: , HPA001122: AB_1080589" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "unprognostic (1.98e-2)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (6.85e-3)" "unprognostic (2.33e-4)" "unprognostic (5.52e-3)" "unprognostic (7.28e-3)" "unprognostic (8.05e-3)" "prognostic unfavorable (9.24e-4)" "unprognostic (5.11e-2)" "unprognostic (2.67e-4)" "unprognostic (8.31e-3)" "unprognostic (1.50e-1)" "unprognostic (3.49e-2)" "unprognostic (2.36e-2)" 1.3 0.8 0.5 3.8 1.0 7.2 2.2 0.9 0.9 1.2 0.1 2.8 1.8 2.1 0.6 2.4 1.6 1.3 0.9 0.7 0.2 1.1 1.2 1.3 5.5 0.2 0.2 1.4 0.9 1.5 0.3 2.8 0.2 1.0 4.0 1.8 0.7 0.8 0.6 2.0 1.7 2.6 0.3 1.7 1.6 5.3 0.4 8.0 0.9 0.8 6.7 1.7 1.1 0.9 39.6 24.7 48.4 21.4 4.6 11.2 28.1 37.5 16.1 29.6 36.0 16.6 25.9 44.9 18.6 10.8 21.4 32.8 72.9 21.5 61.7 30.0 12.7 29.8 23.7 16.2 1.9 56.7 21.8 5.9 3.8 36.6 14.3 7.1 19.6 28.8 37.8 22.0 28.7 21.7 53.5 11.1 38.6 21.1 25.7 49.5 69.7 17.3 8.4 26.0 28.1 19.8 39.8 10.0 12.8 35.1 26.8 11.3 12.8 37.3 43.9 27.5 32.1 6.5 14.4 58.8 17.1 27.4 30.0 1.7 0.3 0.6 0.9 0.2 1.2 1.2 1.0 1.3 0.5 1.8 1.3 1.8 0.4 2.0 0.4 0.7 1.6 0.6 0.5 1.0 0.9 0.9 0.7 0.2 0.2 0.2 0.2 0.3 0.4 0.9 2.3 0.0 2.0 3.9 5.1 3.8 2.2 3.5 3.4 2.9 1.8 1.9 1.7 0.0 4.0 3.7 0.0 8.7 3.6 1.8 0.0 1.8 0.8 1.9 3.1 2.0 0.0 15.5 10.3 1.0 8.4 3.4 2.6 2.5 0.0 12.4 0.7 0.9 4.1 3.3 6.5 2.4 6.1 2.1 1.2 1.1 0.0 2.4 1.8 5.6 1.4 1.4 2.1 4.5 10.1 1.1 0.3 3.0 7.8 0.6 0.5 6.2 3.5 3.1 0.0 2.4 3.0 15.0 19.3 6.1 2.4 2.6 3.6 2.8 5.2 1.7 WDR20 "DMR, FLJ33659, MGC33177" ENSG00000140153 "WD repeat domain 20" Q8TBZ3 14 102139503-102224847 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 241.9;Late spermatids: 250.6;Oligodendrocytes: 201.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" "unprognostic (5.59e-2)" "unprognostic (1.00e-1)" "unprognostic (8.45e-2)" "unprognostic (7.70e-2)" "unprognostic (5.48e-2)" "unprognostic (5.14e-2)" "unprognostic (2.43e-2)" "unprognostic (3.96e-2)" "unprognostic (1.78e-1)" "unprognostic (5.04e-2)" "unprognostic (1.19e-2)" "unprognostic (3.26e-2)" "prognostic favorable (3.26e-9)" "unprognostic (6.62e-2)" "unprognostic (2.01e-1)" "unprognostic (2.68e-2)" "unprognostic (1.41e-2)" 12.2 17.0 11.2 9.4 16.3 10.7 11.7 18.7 15.6 11.5 13.3 10.8 16.0 10.3 12.0 13.5 10.7 8.9 10.0 12.3 15.0 12.5 10.9 8.8 11.5 16.5 14.0 12.3 12.3 11.9 10.5 9.9 16.1 10.2 10.5 29.9 11.4 7.4 11.8 16.0 13.1 9.1 11.6 10.4 10.6 23.9 14.3 12.3 14.1 13.0 10.8 10.4 12.1 28.7 16.2 20.6 14.6 13.0 16.4 14.3 19.2 19.8 16.4 21.9 17.7 17.6 15.2 17.7 12.9 18.6 11.9 19.3 21.6 17.8 27.7 25.0 9.8 9.3 14.8 19.4 12.6 14.4 16.1 11.2 16.7 15.8 15.5 22.0 15.4 14.2 12.3 18.6 23.9 37.2 13.3 21.8 13.0 22.3 22.7 13.3 14.5 11.9 31.8 25.4 18.4 20.8 17.3 22.2 13.9 16.2 24.1 13.8 17.0 20.3 9.3 32.2 18.7 14.6 21.9 18.8 18.5 11.7 22.2 28.5 20.7 37.7 25.8 21.2 27.0 27.6 28.4 24.2 21.0 19.9 28.9 27.4 40.2 30.4 21.4 12.4 33.6 21.0 11.2 16.3 18.7 15.6 12.3 15.0 16.5 14.0 16.1 11.6 14.3 28.7 17.5 9.6 14.5 48.6 21.0 25.1 15.4 19.6 16.5 20.5 16.3 12.7 10.4 10.0 16.7 11.0 16.7 25.6 22.8 19.6 21.5 17.9 241.9 20.1 14.5 12.9 11.4 25.0 43.3 17.3 19.4 15.6 14.3 21.1 22.9 15.0 15.0 12.7 13.4 33.7 42.9 12.8 18.3 10.4 13.8 250.6 13.1 12.9 21.4 48.7 15.6 23.8 22.6 68.9 201.5 18.9 17.6 15.1 17.4 19.0 27.5 25.1 15.6 54.6 13.1 18.6 17.4 43.0 25.3 16.4 27.4 34.9 22.3 8.7 12.1 21.7 WDR72 FLJ38736 ENSG00000166415 "WD repeat domain 72" Q3MJ13 15 53513741-53762878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 105.7;liver: 33.1;thyroid gland: 57.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 12.8;Collecting duct cells: 22.0;Glandular and luminal cells: 13.2;Hepatocytes: 44.3;Proximal tubular cells: 93.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 9.9;OE19: 18.3;RPMI-8226: 17.5;RPTEC TERT1: 10.1;SuSa: 15.2;U-266/70: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048212, HPA057410, HPA059819" Uncertain Approved Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA048212: AB_2680315, HPA057410: AB_2683430, HPA059819: AB_2684133" "unprognostic (6.39e-4)" "unprognostic (1.41e-1)" "unprognostic (3.19e-2)" "unprognostic (1.79e-2)" "unprognostic (2.63e-2)" "unprognostic (3.37e-2)" "unprognostic (5.54e-2)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.26e-1)" "unprognostic (2.78e-2)" "unprognostic (1.09e-2)" "prognostic favorable (3.33e-16)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (7.67e-2)" 0.1 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.1 7.2 0.0 0.6 2.6 1.4 0.5 0.4 2.6 3.9 0.1 0.0 0.1 105.7 33.1 0.8 0.1 0.1 0.4 0.2 3.5 1.8 0.3 0.1 0.1 0.1 0.8 0.7 18.4 0.6 0.0 2.0 0.9 0.0 0.0 0.1 1.1 0.5 0.1 0.0 57.9 0.0 0.0 1.7 0.0 0.3 0.0 9.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 3.2 0.1 6.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.9 18.3 0.1 0.0 0.1 17.5 10.1 3.5 1.9 0.0 0.0 0.1 0.0 15.2 2.4 0.0 0.1 0.3 0.5 0.0 0.1 7.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 6.4 3.6 0.0 0.5 0.1 1.1 0.0 0.6 0.5 0.0 0.1 0.6 12.8 0.0 22.0 0.0 0.6 0.0 0.2 9.8 3.2 1.2 4.9 1.0 0.1 0.0 0.0 0.4 0.5 2.1 0.2 0.0 13.2 0.0 0.0 0.0 44.3 0.1 3.3 0.5 0.0 0.0 0.6 0.0 0.3 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 93.2 0.1 0.1 0.0 0.0 0.1 1.0 1.6 0.9 0.4 0.1 0.7 0.0 0.3 6.4 WDR76 FLJ12973 ENSG00000092470 "WD repeat domain 76" Q9H967 15 43826980-43868412 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.1;lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.3;Spermatocytes: 23.5;Spermatogonia: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039804, HPA040626" Uncertain Approved "Nucleoli fibrillar center,Nuclear bodies" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Nucleoli fibrillar center" "HPA039804: AB_10795297, HPA040626: AB_10795527" "unprognostic (2.26e-1)" "unprognostic (7.56e-3)" "unprognostic (7.05e-2)" "unprognostic (1.88e-1)" "unprognostic (5.85e-2)" "unprognostic (3.12e-2)" "prognostic unfavorable (6.98e-4)" "prognostic unfavorable (8.02e-5)" "unprognostic (4.24e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.91e-2)" "prognostic unfavorable (1.35e-8)" "unprognostic (7.71e-2)" "unprognostic (9.42e-2)" "unprognostic (4.02e-2)" "unprognostic (3.28e-2)" 2.6 1.2 1.0 8.4 1.1 19.1 3.5 4.8 1.7 3.0 0.8 4.8 3.2 3.3 0.9 4.5 1.7 1.9 1.1 0.7 1.1 1.5 2.2 2.4 19.8 1.3 1.1 2.2 3.1 2.7 1.1 3.9 1.3 1.9 6.0 6.3 2.4 2.0 0.8 4.1 3.3 3.9 1.0 3.6 2.9 5.3 1.3 19.5 2.5 1.3 21.3 2.8 2.8 1.2 35.1 17.5 40.7 31.3 4.5 10.7 11.1 57.3 33.9 61.5 76.8 22.1 17.8 51.4 24.8 26.9 31.0 49.4 42.4 20.5 53.1 80.4 25.2 63.3 52.1 7.3 2.5 65.0 27.0 3.4 3.3 33.8 7.7 8.9 19.9 54.7 48.6 86.9 42.6 12.2 63.4 15.4 14.6 11.0 18.1 66.9 70.1 32.4 11.4 35.5 31.3 30.9 36.1 22.5 7.0 12.6 35.0 31.0 9.1 56.3 26.5 63.5 58.9 42.7 114.6 129.1 40.4 56.7 31.5 0.0 0.6 0.3 3.8 0.5 4.1 1.8 4.6 3.4 1.0 2.2 3.8 2.9 0.0 4.8 0.2 1.2 6.6 2.0 1.0 1.1 4.8 1.7 0.7 1.1 1.3 1.1 1.3 1.0 1.3 1.2 4.1 3.2 1.3 2.6 8.2 7.4 3.2 2.4 4.6 3.7 3.7 2.8 1.2 1.5 2.3 1.8 10.4 12.8 6.2 3.5 1.9 2.9 1.7 1.8 3.9 4.8 0.0 35.3 2.5 4.2 13.0 3.9 4.6 3.3 5.7 12.2 2.9 0.9 8.9 1.7 3.3 3.7 0.0 3.5 5.3 0.9 1.8 3.9 3.6 2.8 3.3 8.0 10.3 0.5 1.9 1.1 3.1 2.2 16.1 1.5 1.4 0.9 0.4 16.2 6.6 5.8 5.7 23.5 35.9 7.4 5.8 3.6 11.6 1.5 9.0 1.8 WFDC10B WAP12 ENSG00000182931 "WAP four-disulfide core domain 10B" Q8IUB3 20 45684653-45705019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 27.3;retina: 11.7" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Early spermatids: 5.5;Late spermatids: 10.1;Microglial cells: 3.7;Rod photoreceptor cells: 9.6;Spermatocytes: 4.8" "Cancer enhanced" "Detected in some" "lung cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "PC-3: 1.9" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.14e-1)" "unprognostic (2.31e-1)" "unprognostic (1.37e-4)" "unprognostic (1.60e-1)" "unprognostic (2.69e-1)" "unprognostic (4.81e-2)" "unprognostic (4.30e-3)" "unprognostic (5.64e-2)" "unprognostic (1.14e-2)" "unprognostic (3.36e-1)" "unprognostic (0.00e+0)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" "unprognostic (2.21e-2)" "unprognostic (3.17e-1)" 0.2 0.0 0.2 0.0 0.2 0.0 0.3 0.2 0.6 0.4 0.2 0.6 0.0 0.3 27.3 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.0 0.7 0.0 0.5 0.6 0.1 0.0 0.0 0.1 0.4 0.3 0.7 0.5 11.7 0.0 0.2 0.0 1.2 0.2 0.4 0.4 0.0 0.3 4.3 0.2 0.2 0.0 0.0 0.0 5.9 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.6 1.9 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.2 0.1 0.5 0.6 0.3 0.4 0.2 0.3 0.0 0.0 0.5 3.6 0.0 0.0 0.1 0.4 0.0 0.2 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.3 0.0 0.1 0.0 0.0 1.3 0.4 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.3 0.4 2.0 0.0 0.0 10.1 0.0 0.0 0.0 3.7 0.0 0.9 0.0 1.5 0.9 1.2 0.1 0.0 0.0 0.4 0.3 0.0 0.0 9.6 0.0 0.0 0.1 4.8 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.7 WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 599.7" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 2736.1" "Group enriched" "Detected in many" 5 "endometrial cancer: 16.9;lung cancer: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.2;LHCN-M2: 1.0;NTERA-2: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.96e-3)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (3.26e-3)" "unprognostic (9.66e-2)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (7.94e-2)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-5)" "unprognostic (3.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (7.24e-3)" 1.3 2.7 22.4 0.3 34.3 0.0 22.9 16.3 44.6 1.6 15.0 0.3 0.0 8.6 23.8 4.7 1.5 0.0 0.5 24.8 35.4 0.7 0.0 117.4 0.1 16.6 16.5 1.2 0.3 0.0 46.5 0.0 16.2 14.2 0.3 599.7 45.1 2.8 0.1 6.6 2.2 0.9 16.5 0.1 1.4 0.7 23.4 0.2 0.0 0.7 0.0 1.7 2.2 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 34.3 16.3 44.6 24.8 35.4 16.6 16.5 16.2 16.5 23.4 18.4 0.0 35.3 197.8 186.1 0.0 12.6 34.5 0.0 2.2 25.0 0.7 13.7 1.6 0.0 26.6 1.8 8.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 4.7 0.0 0.0 0.6 0.0 0.0 27.8 0.5 0.1 7.6 1.0 0.0 0.0 0.0 15.2 46.5 0.0 0.0 0.0 20.4 0.0 0.0 0.8 23.2 12.2 0.0 2736.1 0.0 1.5 0.9 0.0 0.0 0.4 0.2 25.5 0.0 1.2 34.2 80.8 0.0 1.8 1.5 2.5 2.0 0.4 10.5 0.0 1.2 0.0 0.0 0.8 WIPF3 "CR16, FLJ36931" ENSG00000122574 "WAS/WASL interacting protein family member 3" A6NGB9 7 29806486-29917066 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;ovary: 41.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.1;Granulosa cells: 149.4;Leydig cells: 50.7;Peritubular cells: 100.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 22.1;cerebral cortex: 49.9;hippocampal formation: 40.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.1;HEK 293: 4.1;K-562: 6.6;NTERA-2: 5.1;RPMI-8226: 11.3;SK-MEL-30: 4.5" "Region enhanced" "Detected in all" "hippocampal formation: 213.9" "Region enhanced" "Detected in all" "hippocampal formation: 156.3" "HPA041145, HPA041211" Uncertain Uncertain Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041145: AB_10795001, HPA041211: AB_10795003" "prognostic favorable (7.93e-4)" "unprognostic (1.35e-1)" "unprognostic (1.37e-3)" "unprognostic (2.12e-3)" "unprognostic (3.65e-3)" "unprognostic (1.53e-1)" "unprognostic (8.95e-3)" "unprognostic (4.53e-2)" "unprognostic (3.49e-1)" "unprognostic (1.19e-2)" "unprognostic (1.08e-2)" "unprognostic (7.49e-2)" "unprognostic (1.61e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-2)" "unprognostic (3.33e-2)" "unprognostic (1.41e-1)" 1.0 5.6 8.7 1.0 22.1 0.5 1.1 0.0 49.9 0.4 0.0 0.7 2.9 3.3 19.7 1.2 8.8 1.4 4.0 40.3 4.2 2.5 0.5 0.5 0.7 0.4 2.6 41.7 1.7 1.2 0.9 0.2 0.1 4.4 0.5 3.8 4.0 4.8 25.0 0.9 2.6 4.1 0.5 1.0 5.9 18.8 7.4 0.4 2.0 8.8 0.7 1.4 0.2 8.1 0.3 1.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 18.1 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.1 0.0 0.1 0.0 0.0 5.1 0.0 3.6 0.0 0.0 11.3 0.0 0.0 1.8 1.5 0.1 0.1 4.5 2.4 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.1 0.0 8.7 22.1 0.0 49.9 40.3 4.2 0.4 2.6 0.1 0.5 7.4 8.1 1.5 0.0 0.0 6.2 0.0 2.2 1.5 0.6 1.2 8.2 4.9 4.6 9.3 0.0 1.4 3.7 2.1 0.0 0.3 0.5 3.9 3.8 1.8 5.0 0.4 4.1 1.8 3.0 45.1 3.5 0.1 7.3 11.7 1.2 0.0 149.4 0.4 0.5 4.5 5.0 27.0 0.7 0.0 0.0 1.0 4.8 50.7 1.0 5.4 1.9 0.0 6.2 0.0 2.0 1.9 2.4 1.5 100.4 0.1 1.1 5.5 5.5 5.1 2.9 6.6 7.2 16.0 4.4 9.9 0.9 0.4 0.0 1.0 8.7 2.0 0.4 WIPI2 "ATG18B, ATG21, CGI-50, DKFZP434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984" ENSG00000157954 "WD repeat domain, phosphoinositide interacting 2" Q9Y4P8 7 5190196-5233840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 255.9;Spermatocytes: 233.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019852, HPA021488" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoplasm "HPA019852: AB_1846589, HPA021488: AB_1846591" "unprognostic (5.79e-2)" "unprognostic (1.47e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (7.69e-5)" "unprognostic (1.96e-3)" "unprognostic (9.27e-3)" "unprognostic (4.60e-3)" "unprognostic (4.96e-2)" "unprognostic (6.60e-2)" "unprognostic (4.23e-1)" "prognostic favorable (9.78e-4)" "unprognostic (1.20e-1)" "prognostic favorable (2.05e-6)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (7.41e-2)" "unprognostic (6.98e-2)" 31.1 30.9 38.8 22.9 40.7 47.0 30.8 35.2 41.8 27.3 37.1 33.9 24.7 32.1 26.3 35.8 29.0 23.2 38.0 42.8 38.6 32.2 35.7 26.4 30.2 36.3 39.1 28.2 37.1 38.2 30.6 32.8 38.7 28.7 20.2 19.1 43.5 28.2 41.3 47.1 26.7 26.8 37.0 29.6 33.6 53.8 38.7 36.8 27.4 45.0 29.2 27.1 30.0 39.8 67.5 42.1 40.4 69.4 60.7 63.3 62.0 58.7 66.9 61.2 64.2 41.2 60.9 47.7 43.9 73.8 76.0 48.2 41.2 47.8 47.4 24.9 64.1 32.7 39.7 45.8 59.9 51.8 34.4 66.9 56.4 69.7 38.3 60.9 86.3 64.3 94.2 41.9 56.2 69.9 39.6 90.0 84.3 35.9 61.1 64.3 57.7 79.5 40.4 32.3 50.3 75.4 43.0 72.8 52.4 67.3 44.8 97.2 69.2 38.9 80.9 65.6 44.4 75.0 75.2 54.7 63.4 59.3 58.8 0.4 4.7 13.6 4.4 6.0 2.8 5.7 5.8 8.0 4.2 6.2 7.5 4.7 9.1 2.6 4.2 6.4 9.0 2.2 38.8 40.7 35.2 41.8 42.8 38.6 36.3 39.1 38.7 37.0 38.7 39.8 40.2 38.5 31.5 16.3 51.6 54.9 39.5 13.9 39.3 71.5 49.4 50.5 37.0 42.9 17.6 18.4 62.6 89.4 62.7 42.6 72.4 43.0 195.8 50.0 38.1 37.9 39.5 125.0 19.7 41.8 96.6 43.1 34.7 48.0 31.1 54.8 54.7 60.4 69.1 47.1 19.6 42.6 18.3 61.4 44.8 255.9 42.6 55.9 44.4 20.6 64.5 89.5 44.3 13.6 23.5 55.6 37.0 56.1 67.7 97.7 48.7 80.6 26.4 52.8 52.6 39.7 39.4 233.0 117.3 49.8 71.0 150.8 46.8 44.1 43.0 69.8 WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Basal keratinocytes: 3.4;Basal prostatic cells: 3.1;Basal squamous epithelial cells: 8.6;Syncytiotrophoblasts: 2.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HEK 293: 1.1;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 9: U-2 OS - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 1.3 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 3.4 3.1 1.2 8.6 0.0 0.0 0.1 1.9 0.0 0.9 1.8 0.0 2.0 0.0 0.4 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 1.0 2.9 0.0 0.0 0.1 0.5 WNT7A Wnt-7a ENSG00000154764 "Wnt family member 7A" O00755 3 13816258-13880071 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;gallbladder: 2.3;placenta: 2.7" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 68.7;Extravillous trophoblasts: 147.5;Pancreatic endocrine cells: 98.8;Syncytiotrophoblasts: 185.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.2;ovarian cancer: 11.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory CD4 T-cell: 1.7;naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Cell line enhanced" "Detected in some" "BEWO: 59.8;EFO-21: 56.0;PC-3: 19.9;RPTEC TERT1: 100.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015719, CAB025894" Approved "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB025894: , HPA015719: AB_1858856" "unprognostic (1.26e-2)" "unprognostic (4.60e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.96e-5)" "unprognostic (3.02e-1)" "unprognostic (1.14e-3)" "unprognostic (2.49e-1)" "unprognostic (3.32e-4)" "unprognostic (2.20e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (7.89e-2)" "unprognostic (3.78e-2)" "unprognostic (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (3.74e-1)" "unprognostic (8.88e-3)" 0.0 0.0 3.6 0.1 3.1 0.1 0.0 1.0 3.7 0.2 0.3 0.0 0.0 1.1 0.2 0.4 0.1 2.3 0.0 2.4 2.1 0.2 0.0 2.0 0.2 5.1 1.9 0.0 0.1 0.0 0.0 2.7 2.5 0.1 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.0 3.4 1.3 0.0 1.3 2.5 0.0 0.0 0.0 0.1 0.3 0.1 2.8 8.6 0.0 0.8 0.0 0.0 0.0 59.8 0.0 0.0 0.0 0.0 0.0 7.6 0.0 56.0 0.0 0.1 11.2 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 1.7 100.3 0.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.6 3.1 1.0 3.7 2.4 2.1 5.1 1.9 2.5 3.4 2.5 2.8 0.0 12.8 0.0 8.5 0.0 5.9 2.8 2.6 0.0 0.0 0.0 0.0 0.7 8.6 1.4 0.0 0.0 68.7 0.0 0.0 0.0 13.8 17.3 14.5 0.4 0.6 0.0 0.0 4.0 9.1 147.5 0.4 0.0 17.9 0.0 0.0 0.0 0.0 7.4 0.0 2.4 0.0 0.0 0.0 0.0 5.6 0.0 0.1 0.0 1.0 0.0 0.0 0.0 4.5 0.3 98.8 0.0 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.2 6.0 2.3 0.0 1.3 185.7 1.5 0.0 0.0 6.0 WWC2 "BOMB, FLJ22029" ENSG00000151718 "WW and C2 domain containing 2" Q6AWC2 4 183099257-183320777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 262.8;Microglial cells: 129.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 84.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044005 Uncertain Approved Microtubules NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Microtubules "HPA044005: AB_10960552" "unprognostic (1.07e-1)" "prognostic unfavorable (8.61e-4)" "unprognostic (7.16e-4)" "unprognostic (1.70e-1)" "unprognostic (2.00e-2)" "unprognostic (4.48e-3)" "unprognostic (2.05e-1)" "unprognostic (3.93e-2)" "unprognostic (4.42e-2)" "unprognostic (1.97e-1)" "unprognostic (9.52e-3)" "unprognostic (2.22e-1)" "prognostic favorable (9.29e-4)" "unprognostic (3.27e-2)" "unprognostic (3.44e-1)" "unprognostic (3.23e-1)" "unprognostic (2.52e-2)" 9.0 5.5 4.7 4.6 5.9 0.6 7.8 5.5 4.4 7.7 10.0 5.0 2.0 8.9 3.3 5.2 6.9 6.9 12.1 4.4 4.4 18.8 19.2 28.2 2.3 7.3 5.8 11.5 12.6 9.7 1.8 14.5 6.3 7.9 2.9 21.3 6.1 8.8 4.2 4.1 2.1 9.9 6.6 6.3 6.8 15.5 5.4 1.0 15.9 5.5 2.2 6.2 3.8 7.7 26.0 10.9 23.1 20.7 16.9 18.8 26.7 34.5 27.1 37.2 26.6 48.2 24.7 0.0 16.9 55.7 13.0 9.2 35.7 14.3 46.9 0.0 11.0 26.3 25.4 24.9 17.5 12.5 27.6 14.3 10.7 24.6 22.9 30.8 25.1 3.7 18.9 1.4 28.6 7.5 0.0 8.3 22.0 0.7 9.3 0.0 21.1 14.0 52.7 6.9 1.5 11.7 84.2 72.7 11.1 36.5 17.6 4.2 37.8 13.8 38.2 8.2 25.1 0.0 0.0 0.3 13.5 5.7 24.7 0.0 0.3 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.4 0.0 0.0 0.0 4.7 5.9 5.5 4.4 4.4 4.4 7.3 5.8 6.3 6.6 5.4 7.7 27.8 262.8 65.4 23.2 0.4 24.0 9.3 6.3 8.6 5.4 15.0 11.4 30.0 37.1 24.0 7.3 64.6 15.4 1.4 0.7 27.4 16.3 36.9 26.7 26.6 27.4 1.2 3.6 62.1 14.6 9.8 25.0 9.2 35.4 19.0 39.5 17.2 39.0 10.5 0.0 98.1 0.2 4.1 15.6 7.7 26.9 17.7 9.0 12.4 129.3 7.6 11.7 0.0 52.3 44.0 30.3 0.1 21.1 0.8 29.3 0.0 24.7 11.5 58.6 26.3 34.2 24.2 41.8 19.7 7.7 15.3 6.6 3.2 19.9 0.4 12.2 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 475.9" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 40.1;HSkMC: 21.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 7.5 0.9 0.1 3.7 0.1 0.2 3.0 0.1 0.1 3.7 0.1 5.5 99.0 2.4 0.1 2.2 6.3 4.3 5.3 0.1 0.1 156.0 23.1 2.1 0.5 0.2 0.1 1.8 0.3 0.3 0.1 1.2 0.1 1.8 6.3 0.0 1.5 0.4 0.5 4.4 166.6 6.0 0.1 0.3 3.4 0.1 0.1 1.0 1.4 2.4 0.4 7.8 4.0 0.1 0.0 0.0 0.5 0.0 8.2 40.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.4 1.2 0.0 1.3 2.8 0.2 0.2 0.4 2.0 0.1 0.0 2.8 0.4 1.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.2 0.5 11.4 5.9 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.0 0.0 10.0 1.1 0.0 0.0 0.0 0.4 18.5 0.8 0.0 0.3 12.8 0.0 1.0 3.6 0.0 0.0 1.0 1.8 1.0 0.0 0.0 3.1 0.0 0.1 0.0 21.0 0.0 0.1 0.0 475.9 75.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.0 1.2 0.9 0.0 8.4 0.0 XRCC2 FANCU ENSG00000196584 "X-ray repair cross complementing 2" O43543 7 152644776-152676141 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 14.1;Extravillous trophoblasts: 21.2;Granulosa cells: 20.2;Spermatocytes: 31.3;Spermatogonia: 19.1;Syncytiotrophoblasts: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065153 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Vesicles" "HPA065153: AB_2685422" "unprognostic (9.31e-3)" "unprognostic (8.25e-2)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (9.10e-2)" "unprognostic (2.52e-2)" "unprognostic (3.36e-5)" "unprognostic (9.98e-3)" "unprognostic (5.82e-3)" "unprognostic (4.04e-3)" "unprognostic (1.06e-3)" "unprognostic (2.43e-2)" "unprognostic (1.55e-15)" "unprognostic (4.52e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-1)" "unprognostic (1.73e-2)" 0.2 0.2 0.9 2.3 0.6 5.3 1.5 1.6 2.8 0.3 0.0 1.1 1.7 1.1 0.9 1.0 0.5 0.4 1.0 0.6 1.9 0.4 0.4 0.5 2.9 0.6 0.6 1.0 0.0 0.6 0.0 2.1 1.4 0.7 1.7 1.9 0.2 0.4 0.1 1.9 1.5 0.5 1.1 1.0 1.0 3.0 1.0 3.6 0.6 0.0 2.5 0.5 0.1 1.9 16.5 10.4 18.3 15.8 1.1 1.8 15.0 11.8 3.9 8.2 10.3 14.7 12.8 24.8 9.5 3.5 13.7 13.7 12.8 7.1 19.3 8.9 17.3 16.8 15.5 10.0 0.3 27.3 9.3 0.9 1.1 15.6 3.6 2.0 3.8 15.5 34.2 22.8 8.3 12.6 32.4 21.2 21.6 10.8 12.9 22.8 19.3 15.3 3.1 10.3 16.7 18.1 11.7 7.6 5.0 11.3 5.4 8.3 4.2 17.2 6.9 13.3 23.0 8.8 14.5 19.0 11.0 20.9 20.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.6 1.6 2.8 0.6 1.9 0.6 0.6 1.4 1.1 1.0 1.9 0.2 0.0 1.1 1.6 1.9 1.3 1.0 1.0 0.0 4.9 0.8 0.4 2.9 0.0 1.4 1.8 0.0 11.2 0.4 0.9 0.0 1.1 11.7 0.9 1.9 1.1 0.0 14.1 2.3 0.2 21.2 2.5 3.1 1.4 0.0 20.2 1.1 0.2 2.4 0.0 2.0 1.7 2.0 0.6 0.8 4.9 0.9 0.8 0.0 0.0 0.6 1.1 3.1 4.5 2.0 0.5 0.1 1.2 6.1 0.6 0.3 0.3 0.1 2.3 0.0 1.9 1.8 31.3 19.1 2.7 1.4 12.6 2.2 1.2 2.3 1.0 YBX3 "CSDA, CSDA1, dbpA, ZONAB" ENSG00000060138 "Y-box binding protein 3" P16989 12 10699089-10723323 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 4915.7;tongue: 1635.6" "Cell type enhanced" "Detected in many" "Early spermatids: 1418.1;Prostatic glandular cells: 1553.4;Skeletal myocytes: 1316.7;Urothelial cells: 1339.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 6.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034838 Approved Supported Cytosol NA NA 230000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA034838: AB_10670980" "unprognostic (1.93e-2)" "unprognostic (6.20e-2)" "unprognostic (3.56e-1)" "unprognostic (3.61e-2)" "unprognostic (4.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (3.81e-2)" "unprognostic (2.91e-1)" "unprognostic (2.41e-1)" "unprognostic (3.23e-3)" "unprognostic (1.20e-1)" "prognostic unfavorable (6.17e-13)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.44e-1)" 250.4 96.7 17.6 77.5 17.6 151.1 200.2 18.8 25.5 152.1 28.4 249.1 37.5 136.8 47.3 271.0 166.7 65.0 469.9 16.5 22.3 194.1 53.8 209.5 32.9 25.4 22.4 134.6 291.0 18.6 84.1 72.5 23.9 177.1 58.8 82.8 218.1 67.5 4915.7 358.1 99.0 100.9 20.9 79.5 149.7 265.7 22.2 36.7 136.1 1635.6 54.6 225.4 204.8 19.7 117.2 90.3 41.4 136.1 165.7 310.7 307.4 173.4 142.7 138.7 132.0 160.4 259.5 109.3 57.7 130.3 96.5 215.5 173.3 338.1 124.6 1.2 325.2 91.3 123.6 108.4 198.3 171.7 10.4 343.3 452.3 124.2 414.6 148.9 313.6 152.3 123.1 0.4 154.7 112.6 137.8 141.9 435.5 103.7 76.9 76.9 192.6 127.4 192.6 150.0 52.2 0.3 129.1 130.9 174.1 288.0 37.1 133.9 221.3 94.5 282.6 108.4 201.5 0.5 38.1 13.4 133.1 0.2 104.8 0.0 4.2 0.0 0.6 4.2 0.0 1.6 0.0 1.5 3.2 6.5 0.0 1.6 0.8 0.8 2.4 0.1 0.1 1.0 17.6 17.6 18.8 25.5 16.5 22.3 25.4 22.4 23.9 20.9 22.2 19.7 680.9 150.6 164.4 14.0 192.8 764.9 1226.9 212.9 552.7 36.1 288.8 292.7 497.7 105.8 177.8 145.3 89.6 145.7 39.2 94.3 133.1 125.3 1418.1 563.0 402.1 563.1 67.6 1081.5 2.4 143.3 84.3 484.8 119.8 551.3 63.3 291.0 235.6 23.1 97.7 16.8 1.0 139.5 120.1 223.2 494.7 470.2 264.7 292.2 259.7 21.5 83.9 67.2 2.1 4.5 0.1 122.0 76.3 223.8 80.6 1553.4 43.9 240.4 240.4 365.4 124.9 1316.7 643.1 594.6 158.4 638.6 1050.5 125.7 72.5 70.8 157.4 1339.7 YWHAQ "14-3-3, HS1" ENSG00000134308 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta" P27348 2 9583967-9630997 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007925, CAB010286" Approved Supported Nucleoplasm,Cytosol NA NA 49000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB010286: AB_2218221, HPA007925: AB_1844340" "unprognostic (2.65e-2)" "unprognostic (3.99e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (1.53e-1)" "unprognostic (5.78e-3)" "prognostic unfavorable (9.83e-6)" "unprognostic (4.90e-3)" "unprognostic (2.98e-2)" "unprognostic (5.51e-2)" "unprognostic (6.18e-2)" "unprognostic (1.45e-1)" "unprognostic (2.95e-2)" "unprognostic (6.74e-2)" "unprognostic (9.75e-2)" "unprognostic (1.63e-1)" "unprognostic (4.39e-3)" 144.6 141.0 190.8 106.1 223.2 178.4 153.6 216.5 239.1 177.0 149.4 161.2 119.4 184.3 141.6 187.3 136.5 122.6 218.7 205.1 229.7 140.0 116.3 119.3 132.0 218.6 203.8 163.2 201.5 131.9 112.9 123.2 212.4 161.1 133.0 143.6 120.2 140.2 53.5 121.5 116.2 177.4 203.9 89.8 127.5 144.6 205.7 148.2 137.6 62.1 141.1 144.4 161.8 280.5 316.1 465.2 412.0 400.3 316.6 434.5 385.7 421.6 412.3 432.5 360.2 352.9 269.3 404.4 214.0 608.5 451.3 288.5 462.8 459.7 553.6 1003.0 374.8 378.8 268.9 379.9 241.1 369.1 219.7 295.8 264.5 473.6 305.9 394.9 493.5 285.6 378.5 236.8 539.3 219.3 658.2 374.4 700.7 351.9 527.5 473.0 533.3 497.4 478.8 276.9 390.1 659.9 384.1 392.2 317.3 343.8 244.4 187.0 453.9 539.6 380.7 473.4 654.4 239.3 351.4 526.6 461.8 378.9 458.8 99.5 102.7 120.5 207.8 137.8 255.6 151.9 192.8 223.5 144.2 147.8 103.6 170.1 31.1 252.0 137.0 73.1 208.4 344.1 190.8 223.2 216.5 239.1 205.1 229.7 218.6 203.8 212.4 203.9 205.7 280.5 186.6 51.3 67.3 26.1 144.0 316.7 366.5 339.0 143.4 201.4 198.4 153.7 82.6 90.1 143.4 136.1 27.1 261.6 189.9 209.9 416.7 371.5 281.9 132.9 175.8 191.0 187.1 179.2 57.3 283.7 615.3 242.0 115.2 131.6 125.0 152.5 84.9 97.9 215.3 572.0 45.1 129.2 270.6 111.9 228.3 360.5 174.0 132.3 295.3 30.0 195.0 229.2 155.5 39.7 186.6 261.2 150.9 250.5 187.9 323.7 135.9 278.8 111.7 105.8 197.2 191.5 312.7 432.2 205.8 252.1 355.3 238.6 217.7 252.9 186.5 457.3 YWHAZ "14-3-3-zeta, KCIP-1, YWHAD" ENSG00000164924 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta" P63104 8 100916523-100953388 "Plasma proteins, Predicted intracellular proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005065 Approved NA NA 320000000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB005065: AB_2218378" "unprognostic (4.70e-3)" "unprognostic (7.38e-3)" "unprognostic (8.09e-2)" "prognostic unfavorable (3.91e-4)" "unprognostic (1.83e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (2.28e-5)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.65e-1)" "unprognostic (3.72e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.03e-6)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" 379.0 262.9 246.2 374.2 324.1 527.2 251.7 147.4 343.0 269.6 88.3 475.2 327.3 275.6 220.9 892.8 243.9 333.0 187.3 366.2 269.6 224.9 190.9 275.8 429.3 163.3 195.7 227.7 191.5 233.3 109.0 339.2 222.5 265.8 445.9 285.3 244.8 291.2 95.0 399.4 375.4 356.5 170.1 272.8 365.4 226.8 276.9 434.8 289.7 168.9 566.1 501.0 343.2 205.0 1902.4 879.2 1605.4 457.7 396.6 490.9 808.0 877.6 1099.2 1124.6 1098.2 602.4 1149.5 816.5 857.1 1349.3 937.2 785.0 1025.5 1213.5 1630.1 765.1 454.2 779.5 579.0 378.1 524.8 311.5 840.3 475.4 1524.0 936.7 1430.1 923.8 1008.7 584.9 887.8 758.9 920.2 660.6 1357.1 535.4 548.0 2269.0 1026.7 569.7 468.6 544.8 1023.1 963.5 889.7 642.7 669.5 609.8 1365.4 1094.7 896.0 374.6 879.0 554.6 834.3 693.7 798.3 503.6 625.3 994.6 925.8 595.2 2303.2 1340.5 427.5 705.8 559.0 589.1 559.3 484.8 463.3 537.3 497.3 395.9 348.3 441.8 616.5 503.7 726.9 313.4 663.9 1087.2 246.2 324.1 147.4 343.0 366.2 269.6 163.3 195.7 222.5 170.1 276.9 205.0 199.4 250.0 228.9 43.1 637.6 1007.0 438.4 309.3 507.6 120.4 285.9 209.9 87.0 188.8 321.3 263.0 89.6 243.4 491.2 552.7 121.3 405.2 1092.9 359.6 245.6 216.0 265.3 137.3 150.2 421.3 551.6 277.4 448.5 578.8 452.9 122.1 183.1 104.5 276.3 134.6 92.5 525.2 244.1 303.5 641.2 2118.0 125.6 456.9 391.3 56.2 334.9 110.9 407.8 51.3 91.5 771.0 452.7 147.1 457.2 427.2 310.6 160.4 292.0 96.3 131.5 229.4 290.4 170.2 92.6 908.0 1184.7 408.9 596.5 116.5 371.7 794.9 ZAN ENSG00000146839 Zonadhesin Q9Y493 7 100733595-100797797 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Early spermatids: 15.0;Late spermatids: 16.2" "Cancer enriched" "Detected in single" 8 "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (3.69e-1)" "unprognostic (4.60e-2)" "unprognostic (5.83e-6)" "unprognostic (9.44e-2)" "unprognostic (4.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.97e-1)" "unprognostic (5.70e-2)" "unprognostic (4.10e-9)" "unprognostic (5.70e-2)" "unprognostic (2.58e-1)" "unprognostic (8.43e-2)" "unprognostic (3.06e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.1 0.1 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713576-97739862 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;lymphoid tissue: 79.9" "Group enriched" "Detected in many" 4 "dendritic cells: 101.0;NK-cells: 155.5;T-cells: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 41 "gdT-cell: 137.4;MAIT T-cell: 93.2;memory CD4 T-cell: 71.7;memory CD8 T-cell: 108.3;naive CD4 T-cell: 50.8;naive CD8 T-cell: 79.8;NK-cell: 112.2;T-reg: 80.1" "Group enriched" "Detected in many" 56 "NK-cells: 112.2;T-cells: 137.4" "Group enriched" "Detected in some" 11 "JURKAT: 121.0;MOLT-4: 183.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002625, HPA003134" Enhanced NA NA 14000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favorable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favorable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favorable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 3.3 1.3 0.5 28.0 0.6 24.8 1.9 0.5 0.9 1.7 0.7 4.0 5.8 1.4 0.5 2.3 2.2 5.4 1.4 0.5 0.7 2.8 3.9 8.7 57.0 0.8 1.3 0.8 1.0 0.4 1.1 0.9 0.7 2.5 1.5 0.0 2.3 0.8 2.0 2.4 18.5 0.5 0.6 35.5 6.7 2.7 1.2 79.9 3.5 2.8 17.7 4.9 2.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 121.0 0.0 0.7 0.0 0.0 183.4 0.5 0.1 0.0 0.0 7.2 0.1 9.1 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 14.1 0.1 0.0 0.0 0.3 0.3 0.5 137.4 0.4 93.2 0.2 71.7 108.3 0.3 1.6 50.8 79.8 2.2 112.2 1.0 0.9 80.1 64.2 0.5 0.6 0.5 0.9 0.5 0.7 0.8 1.3 0.7 0.6 1.2 0.6 0.8 9.6 13.6 0.3 3.9 1.5 0.0 0.0 0.0 0.0 0.8 0.5 3.0 0.0 0.0 0.0 0.0 0.1 101.0 0.2 1.9 0.2 1.0 1.6 0.5 0.8 0.0 8.8 0.2 0.0 0.0 1.8 4.6 0.4 2.5 0.1 2.5 0.7 2.2 0.0 0.2 0.0 0.0 2.8 2.2 0.7 0.0 3.4 1.8 2.8 5.0 0.0 155.5 0.0 0.1 0.0 0.0 0.0 28.0 0.1 0.0 0.5 0.0 0.0 0.0 14.3 0.6 1.3 2.1 0.2 1.4 0.0 105.6 0.1 0.1 0.2 ZBTB22 "BING1, fru, fruitless, ZBTB22A, ZNF297, ZNF297A" ENSG00000236104 "Zinc finger and BTB domain containing 22" O15209 6 33314406-33317942 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043848 Approved Nucleoplasm No No "Cluster 2: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA043848: AB_10961146" "unprognostic (1.32e-1)" "unprognostic (2.87e-1)" "unprognostic (3.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.38e-1)" "unprognostic (2.82e-1)" "unprognostic (1.31e-1)" "unprognostic (1.55e-2)" "unprognostic (2.06e-1)" "unprognostic (6.88e-2)" "unprognostic (4.98e-2)" "unprognostic (1.81e-1)" "unprognostic (6.54e-3)" "unprognostic (1.67e-2)" "unprognostic (2.86e-1)" "unprognostic (1.66e-2)" "unprognostic (9.32e-3)" 10.2 15.1 1.2 2.6 1.2 2.1 11.3 1.1 3.5 15.6 0.7 10.4 4.7 15.6 8.5 13.3 12.6 1.7 10.6 1.2 0.9 11.9 10.1 12.0 1.1 2.1 1.3 14.9 12.2 11.6 10.5 2.3 1.4 12.1 4.2 5.7 12.0 3.8 8.6 19.2 11.6 3.0 1.5 13.7 11.8 6.1 1.0 5.3 15.1 3.9 3.9 12.0 13.2 1.4 0.3 0.3 8.5 4.4 8.3 3.3 3.5 7.5 7.3 7.1 4.6 0.1 1.9 1.9 5.6 12.5 9.1 0.6 0.3 4.6 5.2 11.7 2.8 7.5 4.4 4.1 0.0 0.0 2.8 10.8 10.0 0.3 2.6 9.8 0.7 6.3 2.9 7.8 2.6 4.7 4.6 6.7 0.0 0.4 2.2 0.5 0.1 4.2 6.3 0.4 9.7 0.6 0.7 0.4 4.3 5.0 0.7 0.4 10.7 3.9 4.5 0.2 0.2 4.3 4.5 1.9 5.6 1.1 4.3 0.8 0.2 0.8 0.3 0.3 0.1 0.5 0.4 0.2 0.2 0.3 0.7 0.1 0.3 0.1 0.2 0.4 0.1 0.2 1.2 1.2 1.1 3.5 1.2 0.9 2.1 1.3 1.4 1.5 1.0 1.4 9.4 0.0 5.0 2.6 7.3 6.4 16.3 6.0 8.6 20.1 9.9 7.6 4.3 4.3 4.9 7.3 8.4 6.3 3.3 9.8 23.5 11.0 1.6 8.3 5.2 7.7 7.7 4.0 2.8 7.1 4.6 6.7 5.6 6.9 3.8 6.5 7.9 2.0 5.3 20.2 2.8 8.7 12.2 4.4 4.0 1.8 9.3 5.3 1.8 3.7 12.1 18.2 8.2 3.5 2.6 6.5 8.6 6.4 4.0 10.9 7.6 8.3 6.0 21.2 13.1 10.0 7.6 2.2 2.0 8.1 7.4 10.1 4.9 8.0 5.8 11.8 ZBTB33 "kaiso, WUGSC:H_DJ525N14.1, ZNF-kaiso, ZNF348" ENSG00000177485 "Zinc finger and BTB domain containing 33" Q86T24 X 120250752-120258398 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000755, CAB001980, HPA005732" Approved Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB001980: , HPA000755: AB_1079167, HPA005732: AB_1079166" "unprognostic (9.14e-3)" "unprognostic (1.45e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.47e-2)" "unprognostic (6.13e-2)" "unprognostic (1.72e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (4.51e-2)" "unprognostic (5.08e-3)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (6.44e-2)" "unprognostic (2.59e-2)" 6.4 7.0 6.4 8.5 7.0 19.5 15.4 7.1 9.0 6.8 4.7 6.8 7.7 6.2 9.4 9.9 8.2 7.3 4.9 6.4 9.2 6.4 19.0 8.7 13.2 7.3 8.7 9.7 8.4 13.7 4.8 8.8 8.5 7.4 6.5 5.7 10.4 6.0 5.4 18.8 6.4 4.8 8.4 11.5 8.6 5.7 9.3 16.2 10.2 7.7 12.8 8.0 4.8 9.7 13.6 12.9 19.6 18.1 15.9 17.8 23.4 10.3 13.5 11.7 14.5 9.0 11.7 19.5 18.8 10.4 15.7 20.7 31.9 15.7 15.3 22.0 21.6 20.3 20.3 12.7 11.6 21.2 22.7 12.7 19.9 11.2 17.6 17.1 20.9 18.7 13.5 23.2 14.6 15.6 19.2 14.1 24.3 20.9 15.3 21.9 14.9 32.0 12.5 22.2 35.6 15.2 20.9 21.3 25.3 14.9 11.5 29.6 19.6 9.5 6.9 14.3 18.5 12.7 13.1 24.7 12.6 29.4 11.9 11.5 4.2 5.6 2.9 6.4 5.0 2.4 3.8 3.9 6.2 2.2 4.6 3.4 0.9 4.0 4.2 6.7 3.5 3.6 6.4 7.0 7.1 9.0 6.4 9.2 7.3 8.7 8.5 8.4 9.3 9.7 15.7 16.0 7.0 3.9 7.9 12.7 7.8 5.1 12.5 4.5 11.5 13.1 5.2 8.6 11.9 1.8 0.0 7.7 21.7 5.3 1.9 5.5 0.1 12.9 8.7 8.5 8.4 10.3 3.4 6.7 8.7 7.9 7.1 10.3 0.0 16.0 7.9 16.6 7.6 3.3 4.6 7.0 6.1 12.8 10.3 0.4 4.4 8.2 3.6 3.7 14.6 7.0 14.4 5.0 4.6 6.9 5.7 2.6 5.4 9.5 6.8 4.0 15.3 1.6 6.6 6.9 4.1 5.0 10.0 12.7 13.1 9.3 8.7 11.2 6.0 11.9 ZBTB7B "c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B" ENSG00000160685 "Zinc finger and BTB domain containing 7B" O15156 1 155002630-155018522 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.2;Proximal enterocytes: 158.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006811, HPA025820" Enhanced Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA006811: AB_1859046, HPA025820: AB_1859045" "unprognostic (5.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (4.36e-2)" "unprognostic (2.43e-1)" "unprognostic (4.95e-3)" "unprognostic (9.55e-2)" "unprognostic (1.41e-1)" "unprognostic (3.72e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.46e-2)" "unprognostic (5.35e-2)" "unprognostic (1.11e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" "unprognostic (1.53e-2)" 24.9 35.3 12.9 18.1 15.8 30.0 27.9 15.8 12.9 25.3 11.7 55.4 61.9 16.1 6.4 95.4 17.9 11.0 25.2 11.2 13.6 19.7 48.4 25.0 16.2 18.3 17.5 12.7 29.9 15.6 20.0 9.0 17.3 30.5 18.6 6.5 40.2 12.8 40.6 111.9 71.2 9.9 15.8 31.6 37.7 6.1 17.7 9.0 25.5 17.6 15.2 20.4 44.4 17.9 16.5 29.0 2.5 8.8 12.7 7.2 34.7 11.1 13.1 11.4 13.2 19.5 23.4 7.2 19.5 12.6 9.1 24.5 8.1 15.7 2.4 39.4 9.1 12.0 51.4 13.1 18.6 9.2 31.7 9.4 54.8 15.6 19.3 15.3 9.1 1.1 17.3 32.2 6.7 31.2 0.2 20.7 8.7 26.4 23.8 6.8 1.9 45.6 17.2 16.9 16.1 16.5 21.4 56.5 8.9 10.6 35.2 30.7 7.7 7.4 12.9 14.8 9.5 38.1 25.1 7.6 17.3 30.3 8.6 0.4 1.5 1.3 0.6 1.4 0.2 0.6 0.7 0.3 0.9 0.7 0.6 0.2 2.3 0.7 1.2 0.0 1.0 2.5 12.9 15.8 15.8 12.9 11.2 13.6 18.3 17.5 17.3 15.8 17.7 17.9 6.5 9.6 0.0 11.1 8.5 35.2 9.3 8.8 29.6 13.6 35.2 15.6 2.6 18.6 7.1 5.5 2.1 11.9 6.9 135.2 11.7 13.3 4.3 15.4 6.7 5.6 6.7 6.1 1.0 15.1 14.6 4.9 27.5 21.3 5.7 2.8 6.1 29.9 14.8 16.8 1.1 32.7 14.2 28.7 40.3 8.3 9.0 20.7 16.0 4.7 25.8 5.4 11.3 0.0 8.6 16.8 57.7 7.2 6.8 24.9 158.5 10.0 4.2 10.3 0.0 3.2 5.7 0.5 1.2 51.7 53.6 27.5 11.3 4.4 38.5 24.4 ZCCHC2 "C18orf49, FLJ20222, FLJ20281, KIAA1744" ENSG00000141664 "Zinc finger CCHC-type containing 2" Q9C0B9 18 62523025-62587709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 143.8;Late spermatids: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040943 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA040943: AB_10795496" "unprognostic (9.32e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.84e-3)" "unprognostic (1.40e-1)" "unprognostic (4.07e-2)" "unprognostic (4.79e-2)" "unprognostic (2.60e-1)" "unprognostic (1.93e-1)" "unprognostic (8.25e-2)" "unprognostic (2.32e-2)" "unprognostic (1.30e-1)" "unprognostic (5.12e-2)" "unprognostic (2.45e-1)" "unprognostic (3.72e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" 10.7 5.5 6.2 5.8 6.6 26.5 9.1 9.3 8.2 6.7 6.0 7.1 6.7 6.3 5.9 5.5 7.8 8.6 8.5 5.5 6.9 5.5 23.3 10.2 7.0 7.2 6.8 8.0 6.2 5.8 8.0 8.1 6.7 7.3 5.4 10.0 37.2 5.3 12.2 11.6 7.5 5.8 5.3 9.0 6.4 12.0 6.6 7.6 7.3 7.3 6.3 7.9 6.5 11.5 8.0 6.8 5.8 11.5 17.1 7.3 10.9 4.5 6.7 10.5 10.4 3.7 4.8 22.4 5.8 7.4 8.6 13.2 18.6 9.9 4.3 15.5 8.8 5.9 15.6 25.2 5.9 11.4 8.3 7.2 12.6 6.7 12.3 7.6 19.9 9.9 6.4 7.3 3.5 6.5 7.5 4.8 3.7 5.8 6.7 9.7 6.1 0.1 7.3 8.0 7.2 4.5 7.5 16.8 6.6 10.2 5.9 8.9 8.6 10.3 7.0 4.1 6.5 2.8 5.8 9.4 7.6 4.7 3.9 0.0 0.3 0.8 0.5 0.5 0.4 0.1 0.3 0.4 0.1 0.4 0.6 0.4 1.5 0.2 0.1 0.3 0.4 0.1 6.2 6.6 9.3 8.2 5.5 6.9 7.2 6.8 6.7 5.3 6.6 11.5 23.1 25.6 18.8 28.1 10.8 26.6 16.9 7.5 10.8 33.1 15.2 13.2 18.8 20.0 12.4 16.5 54.2 7.4 33.6 10.2 3.9 6.8 143.8 24.1 12.3 28.8 12.6 8.2 48.5 6.2 10.9 9.7 10.2 27.5 2.5 4.4 17.5 35.4 14.1 43.7 33.9 15.5 2.0 44.4 22.0 158.6 8.1 30.6 7.2 29.0 11.9 7.7 9.2 37.2 51.7 5.1 9.1 7.9 10.7 16.5 8.4 5.3 10.8 19.5 6.6 15.6 15.0 16.3 15.2 15.3 18.5 6.8 22.6 5.6 11.5 12.2 ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type palmitoyltransferase 12" Q96GR4 9 128720870-128724127 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Intermediate filaments" "HPA059339: AB_2683985" "unprognostic (2.05e-1)" "unprognostic (5.81e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-3)" "unprognostic (5.34e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-1)" "unprognostic (6.42e-2)" "unprognostic (9.97e-2)" "unprognostic (9.41e-2)" "unprognostic (1.09e-2)" "unprognostic (8.82e-3)" "unprognostic (2.18e-1)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" 18.8 23.9 7.8 15.5 7.7 41.3 19.3 7.5 9.9 16.8 8.4 40.5 26.3 12.9 7.1 67.8 12.0 14.1 13.7 7.4 8.8 30.6 52.3 23.3 20.0 9.6 7.8 7.4 67.1 9.8 11.3 16.3 8.4 26.6 13.7 0.5 43.2 12.5 15.6 42.4 36.8 6.3 8.4 31.7 49.2 24.7 10.5 12.4 16.2 4.1 13.7 18.7 30.5 9.7 53.5 127.6 6.0 31.3 17.6 12.1 59.4 32.8 28.8 34.5 22.9 109.6 61.5 37.3 29.6 25.5 62.9 139.8 13.0 65.0 3.8 65.0 31.7 20.1 92.7 49.1 34.7 33.1 87.1 19.9 44.7 29.6 11.0 17.7 25.6 65.6 18.8 93.6 7.1 187.3 45.9 66.2 26.8 118.8 107.6 21.0 21.0 108.4 28.7 43.4 42.1 30.4 46.2 64.1 18.3 9.6 98.9 35.6 27.5 0.1 36.9 25.9 45.8 58.1 106.8 17.3 61.3 38.4 41.4 231.1 122.3 385.6 105.1 123.9 91.2 94.6 95.9 101.5 100.1 111.0 99.2 91.4 269.5 90.5 150.0 244.7 130.9 101.0 7.8 7.7 7.5 9.9 7.4 8.8 9.6 7.8 8.4 8.4 10.5 9.7 10.0 16.0 12.0 1.3 31.8 16.2 43.3 94.0 10.8 1.2 55.5 30.4 14.8 77.2 59.0 46.0 0.0 183.9 39.1 171.0 13.7 106.8 73.2 20.7 11.5 21.1 51.2 51.1 0.6 200.0 224.0 14.2 38.7 52.5 18.4 13.7 35.7 55.3 137.0 0.0 0.5 108.5 67.1 62.2 20.9 30.0 9.6 46.5 42.7 6.5 115.3 18.4 81.4 0.5 2.0 133.8 167.7 7.2 43.3 56.5 186.0 48.5 20.1 2.0 6.6 5.4 16.3 36.0 18.6 55.2 28.1 134.1 34.1 22.0 110.0 77.5 ZFP64 "dJ548G19.1, dJ831D17.1, FLJ10734, FLJ12628, ZNF338" ENSG00000020256 "ZFP64 zinc finger protein" Q9NTW7 20 52051663-52204308 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035112, HPA058387" Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA035112: AB_10672859, HPA058387: AB_2683702" "unprognostic (3.86e-2)" "unprognostic (8.84e-2)" "unprognostic (2.34e-1)" "unprognostic (4.61e-3)" "unprognostic (9.22e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.86e-7)" "unprognostic (4.68e-2)" "unprognostic (5.49e-2)" "unprognostic (3.35e-1)" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (1.35e-3)" "unprognostic (2.22e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" 4.2 4.8 5.8 5.7 5.5 5.3 4.6 5.2 5.5 5.7 3.0 6.3 6.6 5.7 4.2 7.0 6.7 5.3 4.8 5.1 3.4 4.7 5.2 4.5 6.6 4.7 3.4 7.8 5.6 7.2 4.7 4.3 4.6 6.3 5.7 5.0 5.8 5.7 5.4 11.2 5.9 5.5 2.6 5.7 5.9 6.6 4.5 7.3 6.8 4.5 5.3 5.6 6.1 5.6 35.1 19.6 14.7 35.1 7.2 13.0 21.0 11.9 17.3 25.5 21.1 18.8 14.3 15.5 23.2 21.5 21.1 46.2 12.0 26.6 15.6 6.6 37.5 9.3 35.0 20.1 19.9 10.4 6.6 11.3 39.4 13.0 14.8 13.0 17.6 16.4 11.2 19.5 6.4 14.6 14.5 8.9 14.8 19.0 15.1 15.9 7.6 15.6 12.1 13.9 15.2 18.0 23.1 28.6 22.5 12.0 19.2 12.3 11.6 18.0 26.1 19.7 7.7 21.1 20.6 12.6 17.2 10.3 12.2 5.1 3.3 8.1 4.5 1.8 3.3 5.1 3.4 3.6 4.2 3.2 3.8 3.7 1.8 5.3 4.8 4.1 3.3 2.8 5.8 5.5 5.2 5.5 5.1 3.4 4.7 3.4 4.6 2.6 4.5 5.6 4.7 3.2 3.3 7.2 5.4 8.7 4.3 5.4 19.9 5.1 5.1 3.9 4.0 4.3 2.5 0.0 2.1 4.3 6.2 7.5 7.9 8.2 7.4 3.9 4.4 4.2 6.7 5.5 18.0 5.8 8.5 5.9 9.7 3.9 7.0 5.2 9.3 6.1 4.0 1.7 15.5 9.5 8.2 4.1 4.2 9.1 6.5 2.9 3.6 14.0 4.0 2.7 7.2 15.6 18.6 5.4 6.0 7.2 11.6 3.5 5.3 4.9 4.0 4.7 6.6 3.8 5.5 19.7 2.9 11.3 13.4 1.2 5.8 3.9 9.0 2.6 ZFPM1 "FOG, FOG1, ZC2HC11A, ZNF89A" ENSG00000179588 "Zinc finger protein, FOG family member 1" Q8IX07 16 88453280-88537031 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 35.3;Muller glia cells: 58.0;Theca cells: 37.4" "Cancer enhanced" "Detected in all" "stomach cancer: 12.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 19.3;K-562: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046603 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA046603: AB_2679718" "unprognostic (1.29e-1)" "unprognostic (2.42e-1)" "unprognostic (3.08e-2)" "unprognostic (3.32e-2)" "unprognostic (1.13e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-1)" "unprognostic (7.13e-3)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (5.58e-2)" "unprognostic (3.05e-2)" "unprognostic (2.49e-4)" "unprognostic (1.99e-2)" "unprognostic (3.32e-1)" "unprognostic (4.89e-2)" "prognostic favorable (4.24e-4)" 2.1 2.5 4.8 1.9 2.4 9.2 1.9 5.7 5.8 2.3 4.2 1.7 12.4 2.2 1.0 1.8 4.0 1.5 4.8 5.8 2.1 3.7 8.6 2.1 2.7 3.5 3.2 2.2 10.4 1.4 5.6 0.8 2.6 3.2 0.8 0.7 2.8 1.3 1.6 3.7 6.8 0.2 1.6 4.9 13.7 5.7 3.3 1.5 4.0 0.3 1.2 2.3 2.0 1.6 1.4 3.8 2.8 5.9 0.5 0.1 11.9 4.0 0.5 1.3 0.4 12.1 1.5 5.9 3.0 0.6 1.4 9.5 0.1 3.3 0.3 4.6 2.5 19.3 8.1 10.7 2.1 1.1 6.2 1.3 2.1 1.4 0.5 1.4 1.3 1.6 29.2 0.4 1.0 7.3 6.9 7.0 1.9 9.3 3.2 2.0 1.3 2.9 1.3 4.8 7.7 12.8 4.9 0.3 3.9 1.4 3.1 3.1 4.8 4.9 3.1 2.2 0.8 1.4 1.0 0.5 1.4 2.3 4.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 2.4 5.7 5.8 5.8 2.1 3.5 3.2 2.6 1.6 3.3 1.6 16.7 3.2 2.2 12.4 4.8 0.9 6.1 0.7 0.0 20.7 13.5 25.8 17.2 5.7 0.4 1.8 29.2 0.4 27.5 10.8 1.9 1.3 0.7 24.1 23.7 6.3 6.0 4.8 6.8 5.1 0.2 10.9 14.3 20.1 0.0 16.0 5.0 8.8 0.9 35.3 8.0 6.7 0.0 5.3 1.2 1.1 0.9 7.5 1.8 8.4 1.6 58.0 2.1 5.5 13.4 2.9 6.2 1.5 9.5 1.4 1.3 1.3 0.4 23.9 0.0 16.1 12.4 0.7 1.0 1.9 1.4 0.3 9.6 37.4 5.2 2.1 ZG16B "HRPE773, JCLN2, PRO1567" ENSG00000162078 "Zymogen granule protein 16B" Q96DA0 16 2830169-2839585 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 717 "salivary gland: 63926.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 194.0;Basal respiratory cells: 181.6;Breast glandular cells: 154.9;Club cells: 343.9;Intestinal goblet cells: 232.2;Prostatic glandular cells: 398.1;Urothelial cells: 357.4" "Cancer enhanced" "Detected in many" "prostate cancer: 47.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.3;intermediate monocyte: 11.4;non-classical monocyte: 7.4" "Lineage enriched" "Detected in many" 7 "monocytes: 11.4" "Cell line enhanced" "Detected in some" "MCF7: 27.1;OE19: 57.5;SK-BR-3: 24.1;T-47d: 22.2" "Not detected" "Not detected" "HPA041125, HPA053549" Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 690000 "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "HPA041125: AB_10794264, HPA053549: AB_2682184" "unprognostic (5.29e-2)" "unprognostic (2.71e-1)" "unprognostic (4.37e-2)" "prognostic favorable (3.48e-6)" "unprognostic (1.39e-3)" "unprognostic (1.94e-2)" "unprognostic (2.34e-3)" "unprognostic (4.13e-2)" "unprognostic (1.01e-1)" "unprognostic (3.45e-3)" "unprognostic (1.37e-1)" "unprognostic (1.47e-2)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.17e-1)" "unprognostic (1.04e-1)" "unprognostic (8.33e-2)" 2.5 13.2 0.0 3.9 0.0 4.6 33.1 0.0 0.1 33.0 0.0 13.6 11.5 0.6 1.5 25.3 4.4 34.4 9.0 0.0 0.0 2.6 8.2 3.3 0.3 0.0 0.8 10.3 46.6 30.4 6.0 4.8 0.1 89.1 17.8 0.0 63926.2 7.1 6.1 47.7 9.6 0.4 0.0 4.2 33.2 4.4 0.0 0.2 2.9 0.1 5.9 11.2 16.3 0.0 0.0 1.1 0.0 0.0 0.3 1.9 0.2 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.3 0.0 0.2 2.1 0.0 4.4 0.0 0.0 0.0 9.0 2.8 2.4 1.6 0.0 0.0 0.1 0.2 0.0 1.2 0.1 0.0 0.0 0.2 3.6 0.2 27.1 0.0 0.4 0.1 57.5 5.0 0.0 0.0 8.6 0.2 6.3 0.0 0.0 0.1 24.1 0.0 0.1 22.2 0.0 3.1 0.1 0.5 1.9 0.1 0.0 0.5 0.3 0.3 6.5 0.3 1.7 6.3 0.0 0.0 11.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.4 1.2 7.4 0.0 0.5 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 9.1 194.0 181.6 0.0 0.0 154.9 82.5 0.0 70.1 343.9 1.8 0.0 0.1 2.0 107.1 0.0 5.9 7.7 3.5 1.6 2.8 58.2 0.4 0.0 28.1 3.2 1.8 21.9 13.0 5.7 1.7 0.7 0.1 14.6 0.0 0.0 232.2 140.4 4.6 0.5 5.7 0.0 4.4 83.6 0.0 5.6 0.0 0.0 0.0 0.0 46.4 65.3 0.0 0.0 398.1 12.5 0.0 74.7 0.0 0.0 0.0 19.2 1.4 0.6 9.5 24.0 0.3 2.5 21.3 76.7 357.4 ZHX3 "KIAA0395, TIX1" ENSG00000174306 "Zinc fingers and homeoboxes 3" Q9H4I2 20 41178448-41317672 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 370.5;Early spermatids: 106.3;Excitatory neurons: 99.0;Inhibitory neurons: 96.5;Oligodendrocyte precursor cells: 139.7;Oligodendrocytes: 142.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046498 Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA046498: AB_2679676" "unprognostic (6.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.50e-2)" "unprognostic (2.29e-1)" "unprognostic (3.88e-1)" "unprognostic (3.42e-1)" "unprognostic (7.25e-3)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.53e-5)" "unprognostic (3.06e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (7.52e-4)" "prognostic unfavorable (1.84e-5)" 14.4 15.4 33.8 6.5 32.8 3.4 13.3 31.6 27.4 11.6 16.4 19.8 8.6 15.8 5.7 13.6 15.7 8.4 12.2 30.2 27.7 26.4 17.2 11.6 4.5 37.6 32.1 16.3 11.9 15.4 7.8 4.9 29.9 10.6 8.0 10.8 5.7 11.9 28.5 11.0 11.4 12.1 29.4 4.3 15.5 35.0 36.0 7.0 19.0 20.1 4.8 18.1 11.0 28.6 22.5 6.3 6.6 14.2 52.6 56.3 7.6 31.0 35.4 28.3 19.1 11.4 2.9 15.6 14.7 58.5 7.6 7.0 7.9 39.2 30.0 4.3 7.1 6.6 8.6 8.8 21.6 7.6 7.9 34.6 18.7 21.3 27.3 19.2 12.3 11.7 6.2 10.6 38.3 45.0 11.9 4.5 2.9 10.4 23.0 5.8 18.6 6.2 38.6 6.7 23.0 8.3 20.7 12.0 7.4 5.7 11.6 10.5 19.9 70.2 10.8 25.0 15.5 12.2 8.0 6.9 28.9 11.0 11.4 0.1 0.1 0.4 0.2 0.1 0.4 0.6 0.2 0.1 0.2 0.6 0.4 0.3 0.1 0.6 0.2 0.1 0.2 0.1 33.8 32.8 31.6 27.4 30.2 27.7 37.6 32.1 29.9 29.4 36.0 28.6 29.8 19.2 16.4 370.5 4.7 2.9 3.9 2.6 2.8 19.5 6.3 4.7 12.7 17.2 5.8 22.0 4.2 0.6 3.8 5.5 11.7 3.7 106.3 12.3 33.2 15.1 14.9 3.8 99.0 2.7 2.7 20.5 6.6 26.3 1.3 3.7 16.4 31.6 3.0 40.4 96.5 5.6 4.1 3.5 1.7 32.3 18.6 3.5 1.8 52.5 1.9 28.6 1.0 139.7 142.4 4.6 1.3 24.5 2.7 2.6 12.6 27.0 3.2 7.1 26.3 41.2 10.9 11.0 5.2 6.3 3.7 0.4 2.7 19.7 4.7 2.3 ZNF106 "SH3BP3, ZFP106, ZNF474" ENSG00000103994 "Zinc finger protein 106" Q9H2Y7 15 42412823-42491141 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 392.5;tongue: 465.5" "Cell type enriched" "Detected in all" 9 "Cardiomyocytes: 1836.4" "Cancer enhanced" "Detected in all" "melanoma: 29.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 161.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054267 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoli "Nucleoplasm, Cytosol" "HPA054267: AB_2682431" "unprognostic (2.15e-2)" "unprognostic (3.31e-1)" "unprognostic (7.10e-2)" "unprognostic (2.61e-2)" "unprognostic (4.01e-2)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" "unprognostic (2.49e-1)" "unprognostic (3.96e-1)" "unprognostic (1.33e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (1.76e-3)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (4.36e-1)" "unprognostic (4.09e-3)" 32.4 11.2 20.8 14.3 29.8 24.4 17.9 19.0 28.1 18.0 109.2 19.7 10.0 15.9 17.3 18.5 12.7 17.2 175.6 23.3 22.6 16.5 8.7 20.9 17.5 23.6 29.1 15.9 10.3 17.8 10.3 12.9 22.5 20.9 13.9 22.0 12.9 14.7 392.5 11.7 13.3 23.0 20.8 17.1 12.8 14.3 27.4 15.6 13.2 465.5 18.6 14.6 9.1 27.7 27.2 15.1 29.0 33.5 86.8 68.5 16.1 21.7 22.2 19.6 20.5 33.9 7.8 17.8 19.0 27.7 22.8 31.8 28.3 23.4 29.5 29.0 13.1 34.7 37.9 13.6 23.2 43.1 20.2 55.4 17.8 28.0 32.6 19.5 32.3 23.2 43.0 2.7 36.9 11.9 16.2 13.3 11.0 26.1 15.1 15.2 54.3 10.8 12.1 31.5 16.5 10.2 45.0 22.8 28.7 23.4 20.0 30.0 42.2 20.8 32.5 26.1 32.3 14.8 32.2 76.5 18.4 33.6 37.6 86.8 63.8 27.1 15.6 52.3 13.5 21.8 13.0 13.3 35.6 26.8 11.3 10.6 161.0 12.5 66.8 36.0 13.0 18.0 20.8 29.8 19.0 28.1 23.3 22.6 23.6 29.1 22.5 20.8 27.4 27.7 58.0 134.6 107.7 46.0 49.6 38.5 57.9 41.9 44.3 58.5 50.9 46.0 1836.4 62.9 57.0 29.5 95.9 37.9 67.2 31.7 41.1 43.2 197.2 75.2 67.1 69.9 40.2 50.5 73.3 42.4 39.3 141.7 31.1 37.5 44.9 49.5 62.8 40.1 53.5 35.3 62.9 32.6 32.6 132.7 43.4 105.2 37.6 89.8 65.8 47.8 124.3 53.6 66.9 31.2 34.2 65.7 26.9 92.6 50.7 74.8 39.7 41.5 161.1 79.9 46.0 151.2 70.0 62.3 38.1 49.8 29.8 30.6 46.0 85.9 36.6 68.2 ZNF134 pHZ-15 ENSG00000213762 "Zinc finger protein 134" P52741 19 57614233-57624724 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA009064 Supported Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA009064: AB_1080668" "unprognostic (3.60e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.88e-1)" "unprognostic (4.29e-2)" "unprognostic (9.62e-2)" "prognostic unfavorable (5.21e-4)" "unprognostic (6.34e-2)" "unprognostic (1.35e-1)" "unprognostic (4.34e-2)" "unprognostic (1.48e-1)" "unprognostic (3.39e-2)" "unprognostic (1.17e-2)" "prognostic favorable (2.61e-4)" "unprognostic (1.56e-2)" "unprognostic (3.40e-1)" "unprognostic (2.52e-2)" "unprognostic (1.34e-1)" 4.6 5.4 4.9 4.7 5.2 12.5 7.5 8.7 5.3 5.7 4.0 6.5 3.5 5.5 6.0 5.3 6.5 4.5 6.0 4.9 5.5 5.6 4.9 5.8 7.5 3.9 4.0 7.6 3.8 12.0 5.7 7.9 3.7 7.3 4.5 10.6 5.4 8.3 6.3 7.1 4.9 6.0 3.6 7.1 6.0 6.6 5.5 11.1 8.3 7.2 8.5 6.1 4.1 4.7 2.5 6.6 15.5 8.4 6.8 9.1 7.7 6.8 11.1 9.8 4.9 2.2 2.9 5.0 4.7 8.5 7.5 2.1 7.2 12.6 16.8 0.1 33.2 15.8 7.0 6.2 9.9 10.6 11.2 12.3 12.1 7.4 16.7 12.9 6.6 8.2 2.1 5.7 14.8 3.7 21.0 4.4 21.8 1.6 13.6 12.2 22.5 7.9 7.3 21.5 12.4 14.5 11.3 4.9 7.2 17.0 6.9 8.4 8.7 14.7 6.3 3.5 9.0 15.3 21.8 6.9 7.7 1.8 9.9 2.3 4.2 7.4 6.3 3.0 8.3 9.5 6.5 6.7 4.6 8.3 7.5 7.5 3.4 11.9 3.4 3.5 4.4 5.5 4.9 5.2 8.7 5.3 4.9 5.5 3.9 4.0 3.7 3.6 5.5 4.7 6.0 9.6 4.1 1.0 14.4 5.4 12.7 4.4 8.6 8.4 9.8 8.0 11.2 11.5 5.6 3.7 12.5 8.2 11.1 1.2 7.9 7.8 1.7 6.0 7.8 8.3 1.2 13.0 1.0 3.7 4.3 6.2 1.1 7.3 6.3 10.6 9.7 4.1 5.3 8.4 0.9 4.0 6.1 5.1 3.2 1.5 7.2 4.4 3.6 0.0 7.0 11.3 9.2 1.0 1.6 3.8 2.6 14.7 5.0 9.3 2.8 4.6 5.1 11.9 6.6 6.6 8.5 2.2 15.2 6.7 7.7 16.3 8.8 8.0 3.6 13.8 ZNF22 "HKR-T1, KOX15, Zfp422, ZNF422" ENSG00000165512 "Zinc finger protein 22" P17026 10 45000923-45005326 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 184.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016736, HPA054893" Approved Enhanced Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA016736: AB_1859133, HPA054893: AB_2682632" "unprognostic (2.87e-2)" "unprognostic (1.10e-1)" "unprognostic (2.65e-1)" "unprognostic (5.77e-2)" "unprognostic (3.50e-3)" "unprognostic (3.42e-2)" "unprognostic (4.77e-2)" "unprognostic (2.01e-1)" "unprognostic (1.01e-3)" "unprognostic (9.31e-3)" "unprognostic (2.94e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.11e-5)" "prognostic unfavorable (8.06e-4)" "unprognostic (1.39e-1)" "unprognostic (9.96e-2)" "unprognostic (4.58e-2)" 28.3 13.5 19.8 21.9 21.3 25.7 41.1 20.5 26.1 22.8 18.1 21.0 18.9 30.6 23.5 10.9 25.7 17.6 23.9 19.1 21.0 25.2 38.7 23.1 36.1 25.1 20.7 35.8 39.6 13.3 8.6 40.0 21.5 22.8 21.6 19.2 22.7 19.6 21.1 8.4 18.2 23.9 21.4 27.1 22.8 9.0 20.9 70.4 23.9 25.7 35.1 18.1 10.9 22.9 46.7 7.4 63.3 39.3 32.1 23.2 0.5 21.6 44.5 54.7 58.8 25.5 38.6 48.4 33.5 32.5 12.0 7.8 62.1 23.2 77.3 30.3 1.1 50.3 11.3 0.3 68.8 98.5 17.0 41.6 33.3 22.3 0.9 0.5 87.7 127.8 67.8 84.9 43.7 1.4 184.0 148.5 38.0 26.8 12.9 133.8 87.8 69.4 43.0 39.2 60.5 52.7 19.3 38.8 32.3 57.5 8.4 96.7 48.4 39.2 72.2 27.2 73.3 48.0 51.0 46.4 24.4 3.6 42.6 28.2 28.1 37.6 51.7 27.5 62.5 42.2 33.6 53.8 37.8 54.4 45.3 56.6 2.9 70.8 18.3 64.7 21.1 38.1 19.8 21.3 20.5 26.1 19.1 21.0 25.1 20.7 21.5 21.4 20.9 22.9 69.3 28.9 27.4 5.9 45.7 19.2 65.5 34.1 42.1 33.6 51.2 68.6 9.9 68.6 25.2 33.1 10.4 71.7 48.0 7.0 56.7 58.7 6.3 22.1 48.7 72.9 40.0 67.5 5.0 43.3 55.8 49.5 21.4 25.4 33.5 59.1 91.8 58.6 49.3 38.7 7.6 37.2 38.7 28.7 28.4 3.6 44.4 32.7 19.6 4.7 61.4 57.2 89.6 7.5 11.3 35.7 15.1 51.1 31.9 57.9 6.9 54.6 28.4 32.7 32.9 77.1 48.4 40.1 37.1 23.9 13.2 53.2 36.4 58.7 34.7 27.6 ZNF250 "MGC9718, ZFP647, ZNF647" ENSG00000196150 "Zinc finger protein 250" P15622 8 144876497-144902168 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020853 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" Cytosol "HPA020853: AB_1859152" "unprognostic (1.16e-3)" "unprognostic (9.56e-2)" "unprognostic (2.63e-1)" "unprognostic (2.60e-3)" "unprognostic (1.03e-1)" "unprognostic (5.95e-3)" "unprognostic (3.73e-3)" "unprognostic (2.72e-2)" "unprognostic (6.27e-2)" "unprognostic (7.37e-2)" "unprognostic (4.94e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.43e-7)" "unprognostic (2.23e-1)" "unprognostic (6.79e-2)" "unprognostic (5.82e-2)" "prognostic favorable (8.26e-4)" 4.7 3.9 3.2 3.3 3.2 2.9 5.6 10.5 4.7 9.7 2.3 6.9 4.8 7.4 2.8 6.4 7.6 3.3 4.9 2.4 4.5 7.6 4.0 5.1 3.0 3.0 3.2 9.7 4.9 6.0 7.3 5.5 3.3 7.5 3.6 7.9 6.0 5.2 4.8 10.9 5.2 4.2 1.5 5.5 4.9 4.5 3.3 4.5 10.0 5.8 3.3 6.3 8.6 3.4 5.1 2.9 13.4 11.1 6.8 5.9 4.3 5.6 6.4 9.4 7.7 2.4 3.9 12.0 9.8 6.5 3.8 6.6 5.3 4.8 6.0 3.8 7.8 10.8 14.9 3.5 2.0 1.8 3.6 3.9 6.5 5.6 4.5 7.2 3.9 7.1 8.6 11.5 7.9 6.8 12.6 4.1 4.0 6.0 12.5 14.4 5.9 5.0 7.8 3.7 13.2 10.1 11.8 4.4 5.3 5.3 6.3 6.1 5.1 9.2 8.8 7.3 5.3 5.6 5.1 8.0 4.7 6.2 4.1 3.2 5.1 5.8 10.5 2.7 8.1 10.3 7.7 5.8 6.6 9.7 8.9 7.3 2.9 6.0 3.7 2.6 11.7 4.5 3.2 3.2 10.5 4.7 2.4 4.5 3.0 3.2 3.3 1.5 3.3 3.4 5.8 12.8 3.0 10.7 10.7 5.5 3.2 7.5 10.2 8.4 4.3 6.6 4.3 1.5 3.9 5.5 0.0 2.3 18.6 2.4 3.9 7.5 7.4 5.1 6.0 5.5 4.2 1.7 11.9 1.9 1.3 5.2 2.6 4.9 2.5 6.3 5.0 2.1 1.7 8.4 17.5 1.9 12.2 2.2 8.0 3.0 4.1 3.0 5.4 4.7 2.0 3.3 5.2 11.1 7.8 2.6 1.0 5.3 8.2 3.3 3.7 3.4 5.0 9.9 13.1 4.1 6.1 14.3 8.7 4.4 5.5 1.9 10.9 4.9 3.4 2.3 ZNF367 FLJ33970 ENSG00000165244 "Zinc finger protein 367" Q7RTV3 9 96385941-96418370 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA015319, HPA015785" Uncertain Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA015319: AB_2669185, HPA015785: AB_2217750" "unprognostic (5.91e-2)" "unprognostic (2.78e-3)" "unprognostic (2.17e-2)" "unprognostic (1.11e-2)" "unprognostic (2.36e-1)" "unprognostic (4.57e-3)" "unprognostic (7.76e-3)" "unprognostic (1.60e-3)" "unprognostic (4.35e-2)" "unprognostic (3.01e-1)" "unprognostic (3.78e-3)" "unprognostic (2.71e-2)" "unprognostic (4.88e-3)" "unprognostic (3.23e-3)" "unprognostic (1.72e-1)" "prognostic favorable (2.34e-4)" "unprognostic (2.28e-1)" 1.4 0.6 0.7 3.7 1.3 26.1 1.7 1.4 1.3 1.1 0.2 3.0 2.9 1.1 0.1 2.4 0.7 1.0 2.1 0.7 1.0 3.0 10.8 1.1 4.6 1.5 1.4 1.0 1.4 1.6 0.3 1.9 1.4 1.2 3.3 1.3 0.7 0.4 1.5 3.5 3.0 2.4 0.9 1.3 2.1 6.1 1.3 8.7 1.1 2.7 4.7 1.5 1.2 2.7 25.4 10.3 9.9 8.9 3.8 5.3 13.4 34.6 20.4 16.9 20.0 6.4 17.5 19.2 14.4 16.5 12.6 30.5 11.6 12.6 19.9 21.2 10.0 14.0 19.1 5.3 0.0 19.8 16.5 0.9 0.8 13.7 6.9 3.7 6.3 13.3 13.0 45.4 21.7 16.9 30.4 16.1 6.7 27.9 16.7 15.3 49.9 11.7 4.9 16.8 17.4 12.0 15.3 18.1 10.6 8.0 9.4 17.3 5.7 27.6 15.8 25.6 26.6 17.6 32.0 7.8 16.7 17.0 23.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.7 1.3 1.4 1.3 0.7 1.0 1.5 1.4 1.4 0.9 1.3 2.7 1.1 0.0 0.0 2.9 3.8 9.9 1.3 0.4 10.8 0.7 2.2 2.3 2.6 0.0 0.9 0.0 0.0 3.2 2.5 2.4 0.0 0.5 0.7 0.6 1.1 2.0 0.0 22.3 5.1 1.2 4.2 1.7 2.6 1.8 0.0 4.7 1.1 3.8 1.9 0.0 5.3 3.6 0.0 2.1 2.6 0.8 0.6 8.3 3.6 2.8 0.1 0.6 1.0 3.0 7.9 0.7 0.5 0.7 9.6 0.6 0.9 2.5 0.0 1.5 6.6 2.0 3.6 10.3 1.7 10.9 6.5 0.8 5.0 0.3 5.6 1.1 ZNF385B "FLJ25270, ZNF533" ENSG00000144331 "Zinc finger protein 385B" Q569K4 2 179441982-179861612 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 88.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 124.2;Bipolar cells: 220.1;Excitatory neurons: 566.5;Inhibitory neurons: 393.1;Rod photoreceptor cells: 133.7" "Cancer enhanced" "Detected in many" "prostate cancer: 6.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 17.6;HAP1: 31.9;U-698: 91.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046086 Approved "Nucleoli fibrillar center" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "HPA046086: AB_2679532" "prognostic favorable (4.86e-8)" "unprognostic (8.05e-3)" "unprognostic (1.14e-1)" "unprognostic (3.91e-2)" "unprognostic (3.49e-1)" "unprognostic (1.51e-2)" "unprognostic (3.49e-3)" "unprognostic (1.14e-1)" "unprognostic (8.99e-3)" "unprognostic (3.56e-2)" "unprognostic (4.59e-2)" "unprognostic (2.69e-1)" "prognostic favorable (1.04e-9)" "unprognostic (7.76e-2)" "unprognostic (2.94e-2)" "unprognostic (3.35e-2)" "unprognostic (1.20e-3)" 2.3 5.2 4.1 0.3 25.4 0.4 6.9 27.3 17.4 1.6 0.0 2.4 0.3 1.5 3.8 1.1 1.1 0.7 24.1 6.9 1.9 8.5 19.1 18.4 1.6 9.6 3.0 15.2 0.3 0.0 1.0 2.2 10.8 12.6 0.7 88.7 1.2 0.5 17.1 1.6 0.8 0.4 0.0 0.5 14.2 10.3 6.8 0.5 1.2 10.9 0.6 1.5 2.2 9.5 0.0 0.0 7.3 0.3 0.1 0.3 0.1 0.0 0.0 0.4 0.8 0.0 0.0 17.6 0.1 0.0 5.9 0.0 31.9 0.0 0.4 0.0 4.3 0.2 0.7 1.2 0.0 0.0 0.0 3.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.3 0.1 0.1 1.3 0.0 2.0 0.0 1.3 1.3 1.8 0.0 0.7 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.3 2.3 0.3 1.5 0.0 0.0 91.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 25.4 27.3 17.4 6.9 1.9 9.6 3.0 10.8 0.0 6.8 9.5 1.0 28.9 124.2 12.1 0.0 3.4 0.7 0.0 0.0 220.1 5.1 2.2 32.4 5.7 1.3 0.0 54.2 0.0 0.0 0.3 82.2 0.0 58.4 1.0 0.1 0.5 1.8 0.0 566.5 0.0 0.0 6.4 3.1 1.7 1.3 19.6 1.4 14.3 0.3 1.7 393.1 0.0 0.0 0.0 0.3 29.2 0.6 0.5 1.8 89.0 0.0 6.4 0.0 20.1 10.7 0.1 0.0 0.4 0.1 4.9 0.0 24.5 1.5 133.7 0.0 5.2 1.6 6.2 1.8 0.1 0.9 0.1 0.3 3.3 0.1 0.9 ZNF385D "FLJ22419, ZNF659" ENSG00000151789 "Zinc finger protein 385D" Q9H6B1 3 21412218-22373321 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 44.0;testis: 15.1" "Cell type enriched" "Detected in many" 5 "Inhibitory neurons: 1766.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 8 "cerebellum: 44.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.8;hTERT-RPE1: 5.4;LHCN-M2: 5.3;PC-3: 5.3;RPTEC TERT1: 15.1;U-87 MG: 21.1" "Low region specificity" "Detected in all" HPA036190 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA036190: AB_10602355" "unprognostic (4.07e-2)" "unprognostic (1.26e-1)" "unprognostic (5.44e-2)" "unprognostic (3.23e-2)" "unprognostic (1.64e-1)" "unprognostic (1.74e-1)" "unprognostic (8.20e-2)" "unprognostic (6.60e-2)" "unprognostic (7.84e-2)" "unprognostic (3.73e-1)" "unprognostic (2.35e-1)" "unprognostic (9.01e-2)" "unprognostic (3.49e-7)" "unprognostic (8.70e-3)" "unprognostic (5.38e-2)" "unprognostic (7.76e-3)" "unprognostic (2.15e-5)" 3.8 0.2 2.6 1.4 4.5 0.3 2.2 44.0 5.4 1.8 0.0 0.8 0.3 1.1 0.5 2.0 0.7 2.7 1.8 1.7 2.5 1.4 0.1 0.6 0.8 3.3 4.5 0.6 0.6 0.2 0.1 0.0 3.6 1.3 0.5 7.3 0.7 1.1 1.0 0.7 0.5 1.7 1.5 0.3 0.4 15.1 3.1 0.7 0.5 3.3 1.0 2.7 1.2 5.3 0.0 0.0 0.3 0.0 2.0 4.3 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.2 0.0 5.4 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.5 0.0 5.3 0.0 0.0 0.0 15.1 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.1 0.0 0.0 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 2.6 4.5 44.0 5.4 1.7 2.5 3.3 4.5 3.6 1.5 3.1 5.3 82.2 12.8 13.4 17.3 1.4 9.7 0.7 6.2 1.8 58.8 1.5 6.3 3.6 1.5 19.2 1.8 8.4 0.3 1.4 0.9 27.4 0.6 174.9 0.2 1.9 89.0 0.0 12.6 267.5 0.7 0.2 20.5 0.0 0.3 5.1 1.8 2.2 5.8 0.4 323.0 1766.6 0.7 0.0 0.0 14.0 274.5 16.8 4.9 12.4 64.6 0.6 114.3 1.0 159.3 12.7 1.4 0.6 13.5 0.3 1.7 2.3 6.6 4.4 31.0 13.1 22.0 20.2 50.4 2.0 0.6 7.7 0.1 1.5 34.3 0.7 1.0 ZNF410 "APA-1, APA1" ENSG00000119725 "Zinc finger protein 410" Q86VK4 14 73886617-73932521 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 27.7;Excitatory neurons: 22.7;Inhibitory neurons: 23.8;Oligodendrocytes: 31.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002871 Approved "Nuclear bodies" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Nuclear bodies" "HPA002871: AB_1080712" "unprognostic (5.84e-2)" "unprognostic (5.04e-2)" "unprognostic (9.29e-2)" "unprognostic (6.36e-3)" "unprognostic (5.86e-4)" "unprognostic (4.91e-2)" "unprognostic (2.83e-3)" "unprognostic (2.10e-2)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (1.86e-3)" "unprognostic (1.29e-2)" "unprognostic (3.73e-2)" "unprognostic (2.79e-2)" "unprognostic (2.46e-1)" "unprognostic (3.21e-2)" "unprognostic (1.19e-1)" 29.0 33.0 26.8 18.7 30.4 57.7 29.4 30.9 33.9 30.0 28.9 30.6 19.0 27.5 43.7 33.4 28.1 22.6 21.0 26.3 28.0 33.0 28.8 27.6 25.6 29.1 27.5 38.7 20.6 27.1 27.0 32.2 29.6 29.5 24.4 22.8 24.4 27.3 21.1 37.6 25.2 28.4 26.7 26.1 25.7 44.7 28.3 29.9 24.6 18.3 30.7 29.1 28.7 37.0 46.7 35.8 42.4 45.2 44.8 39.8 52.4 51.4 56.9 88.2 82.0 37.6 40.1 38.4 21.7 65.7 28.2 42.1 42.9 52.8 83.2 56.2 26.9 36.2 31.6 29.9 67.4 30.6 45.6 37.0 72.4 44.5 83.1 39.5 47.5 43.9 38.2 33.0 43.3 88.6 45.8 51.2 15.5 56.3 41.7 40.7 48.5 24.7 57.0 43.7 39.0 50.3 57.2 52.5 54.6 35.5 48.3 52.2 30.7 62.7 59.0 37.1 47.2 45.2 83.4 48.0 40.1 34.1 53.7 65.9 45.3 74.8 47.5 43.1 51.9 37.7 49.0 49.0 45.6 43.0 42.3 43.5 34.4 60.5 50.1 30.8 46.7 55.9 26.8 30.4 30.9 33.9 26.3 28.0 29.1 27.5 29.6 26.7 28.3 37.0 4.3 0.0 3.1 27.7 10.8 0.6 1.5 1.0 10.8 1.5 2.2 1.7 1.1 0.0 2.9 0.0 4.2 1.8 5.0 1.7 0.0 1.0 3.8 4.7 5.6 2.6 0.0 5.9 22.7 0.9 1.5 5.3 10.7 6.7 10.8 2.9 1.8 0.4 1.2 1.7 23.8 1.1 0.0 2.2 3.1 1.1 1.2 5.4 1.8 18.7 1.1 2.4 2.1 18.1 31.0 1.3 1.4 0.4 13.4 1.0 2.4 0.7 0.2 4.7 0.0 4.0 5.1 3.3 1.9 10.1 1.1 2.6 10.5 4.1 0.8 1.4 ZNF416 FLJ20557 ENSG00000083817 "Zinc finger protein 416" Q9BWM5 19 57571566-57578911 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA063318 Approved "Nuclear bodies,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nuclear bodies" "HPA063318: AB_2684983" "unprognostic (1.40e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.99e-2)" "unprognostic (1.14e-2)" "unprognostic (7.57e-3)" "unprognostic (3.66e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (8.54e-2)" "unprognostic (6.62e-3)" "unprognostic (5.37e-2)" "prognostic favorable (1.20e-5)" "unprognostic (1.31e-1)" "unprognostic (2.62e-1)" "unprognostic (8.03e-3)" "unprognostic (1.70e-1)" 2.2 2.2 2.6 1.6 3.0 2.6 3.7 4.3 3.7 2.7 2.2 2.3 1.4 2.3 3.9 3.2 3.4 1.8 2.7 2.7 2.5 2.6 2.0 2.5 2.8 2.0 2.2 4.4 1.4 4.4 2.0 2.9 2.0 2.7 2.1 3.7 2.2 3.1 2.6 5.1 1.7 2.8 2.2 2.8 2.1 4.2 2.6 4.0 3.6 3.0 4.1 2.4 2.4 2.9 3.2 3.1 6.5 5.2 3.9 5.6 4.3 3.2 5.8 6.2 4.0 2.2 1.7 2.2 2.3 4.1 4.5 1.2 3.8 5.5 7.6 3.5 15.5 5.3 3.5 1.8 7.0 4.7 3.3 5.6 5.6 3.9 8.2 4.9 4.3 5.3 0.7 1.7 8.4 1.3 9.9 2.2 7.7 3.8 5.7 4.9 9.7 4.8 4.3 6.8 4.7 5.3 5.8 3.0 2.9 7.3 2.7 5.6 3.2 6.7 3.2 2.2 4.8 5.4 9.5 5.9 1.5 3.1 4.1 1.1 2.6 1.9 4.3 1.9 7.7 6.6 5.9 6.3 4.1 10.4 8.0 5.8 0.8 9.0 1.7 3.7 2.9 3.7 2.6 3.0 4.3 3.7 2.7 2.5 2.0 2.2 2.0 2.2 2.6 2.9 1.1 0.0 0.5 1.3 2.9 1.7 1.6 1.6 1.2 3.5 1.6 1.8 1.8 1.5 1.6 0.0 0.0 2.1 1.0 0.6 3.9 2.8 5.0 0.9 0.9 1.8 0.0 3.6 1.5 0.9 0.8 1.1 1.5 1.1 2.5 2.6 0.7 1.2 1.7 8.4 1.4 1.1 0.0 1.0 0.6 2.0 0.9 0.6 0.0 1.0 0.5 3.2 3.1 3.0 0.2 1.4 1.2 0.7 0.8 1.3 1.1 1.3 0.6 2.8 6.6 1.5 1.2 3.1 4.1 1.3 2.4 1.9 1.3 2.4 0.9 2.2 ZNF43 "HTF6, KOX27, ZNF39L1" ENSG00000198521 "Zinc finger protein 43" P17038 19 21804946-21852125 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 52.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 37.8" HPA050271 Uncertain NA NA "Cluster 30: Non-specific - Translation" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA050271: AB_2681070" "unprognostic (9.25e-3)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (2.50e-2)" "unprognostic (1.25e-1)" "unprognostic (4.16e-3)" "unprognostic (3.61e-2)" "unprognostic (2.47e-3)" "unprognostic (4.45e-3)" "prognostic favorable (3.16e-5)" "unprognostic (2.73e-2)" "unprognostic (1.01e-1)" "unprognostic (3.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.50e-1)" "unprognostic (3.37e-3)" "unprognostic (1.43e-3)" 3.9 4.0 1.6 5.5 4.1 10.7 7.8 10.6 3.0 4.9 1.1 4.4 3.6 6.3 4.6 3.6 6.8 4.0 4.5 1.5 5.2 5.0 1.4 4.2 8.4 2.9 1.9 11.2 3.0 6.7 2.6 4.8 3.2 7.2 5.3 6.7 3.5 4.9 3.1 7.3 4.2 4.4 0.8 6.6 4.8 8.7 2.9 10.1 8.7 4.1 6.8 3.6 3.1 7.7 0.4 3.7 25.0 19.8 2.7 5.9 10.4 6.6 2.7 8.3 11.4 0.3 3.8 5.9 7.5 4.2 7.7 0.5 0.3 0.7 13.8 0.8 6.5 0.3 1.6 2.9 1.3 0.2 7.2 5.6 0.9 8.9 0.4 2.1 1.9 21.8 0.4 1.1 6.3 4.3 37.8 9.1 18.0 0.5 5.4 22.0 9.8 6.6 5.4 18.9 16.7 12.6 0.1 0.1 2.2 11.3 9.6 5.1 0.4 0.7 0.8 6.0 7.0 1.5 11.3 10.2 0.3 0.8 0.8 30.7 4.5 6.2 8.8 4.6 8.4 18.8 11.5 9.9 4.6 19.1 18.6 12.7 4.5 9.0 4.0 8.5 8.1 3.9 1.6 4.1 10.6 3.0 1.5 5.2 2.9 1.9 3.2 0.8 2.9 7.7 17.0 12.8 15.1 19.2 14.4 2.0 8.1 1.4 2.8 16.0 10.6 12.2 13.2 8.6 9.9 3.7 10.4 9.4 10.6 3.7 17.6 11.0 36.3 11.6 13.6 16.0 11.4 16.2 9.5 9.4 7.6 12.8 5.1 16.6 16.4 52.0 16.8 0.4 4.8 8.4 14.1 4.2 6.1 4.4 4.4 9.8 14.0 6.6 1.8 18.7 6.5 12.5 20.6 26.7 23.1 7.6 4.0 9.4 7.7 8.8 2.4 7.4 6.6 9.6 6.6 13.8 13.3 21.3 15.7 3.3 2.0 5.9 10.8 41.0 7.1 4.4 ZNF496 "MGC15548, ZKSCAN17, ZSCAN49" ENSG00000162714 "Zinc finger protein 496" Q96IT1 1 247297412-247331846 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025824 Approved Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA025824: " "unprognostic (1.88e-3)" "unprognostic (3.31e-2)" "unprognostic (2.48e-2)" "unprognostic (1.23e-1)" "unprognostic (5.87e-2)" "unprognostic (6.88e-2)" "unprognostic (3.72e-3)" "unprognostic (3.31e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (6.41e-2)" "unprognostic (4.19e-1)" "unprognostic (1.89e-3)" "unprognostic (8.24e-2)" "unprognostic (1.86e-1)" "unprognostic (2.25e-2)" "unprognostic (2.55e-1)" 8.6 6.0 7.8 5.4 8.1 6.8 8.1 6.8 8.2 13.6 6.3 11.6 3.8 14.3 5.5 5.6 14.7 7.8 9.0 7.0 7.4 8.7 3.6 8.5 6.9 7.4 7.5 18.7 15.4 11.3 6.4 9.9 7.0 9.4 5.6 5.7 7.8 8.4 15.6 5.8 6.8 11.5 6.9 9.2 9.0 10.8 8.2 23.8 12.3 13.7 5.4 9.2 8.0 8.4 20.8 18.7 19.4 23.7 7.5 19.1 24.2 9.5 23.5 20.9 18.8 10.3 18.9 5.9 16.1 15.6 7.8 17.4 20.1 18.3 20.8 16.0 4.8 19.2 13.1 11.8 20.3 23.5 9.5 20.4 19.0 16.2 38.9 23.2 25.1 27.3 34.6 14.5 13.1 13.3 23.4 16.2 39.0 9.2 27.5 22.0 21.2 8.1 12.8 24.8 16.5 36.4 12.7 14.3 19.0 17.6 14.9 28.7 17.4 15.1 21.4 6.9 30.2 16.1 13.8 16.8 6.3 1.6 16.8 0.0 0.4 0.1 0.8 0.3 1.2 0.3 0.3 0.9 1.1 0.4 0.7 2.1 0.1 1.1 0.4 0.7 0.1 0.8 7.8 8.1 6.8 8.2 7.0 7.4 7.4 7.5 7.0 6.9 8.2 8.4 9.2 0.0 3.2 16.3 3.3 3.7 4.4 5.0 8.0 7.4 7.0 7.5 8.3 5.7 4.7 1.8 2.1 4.8 2.4 1.2 1.9 4.4 11.2 4.9 7.5 7.5 4.9 3.0 13.0 6.0 5.8 6.8 7.1 6.5 3.8 13.7 7.1 2.3 6.0 3.3 16.9 2.5 2.0 5.1 3.6 40.0 5.6 4.0 3.6 9.4 3.4 1.7 5.2 18.6 10.8 4.9 2.6 7.2 7.5 7.5 0.8 3.0 3.9 7.3 6.6 9.7 6.2 15.9 10.8 2.4 3.4 4.2 4.7 7.5 4.3 4.3 ZNF526 "KIAA1951, MGC4267" ENSG00000167625 "Zinc finger protein 526" Q8TF50 19 42220312-42228201 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 33.3;granulocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023070, HPA056609" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA023070: AB_2671057, HPA056609: AB_2683189" "unprognostic (2.04e-1)" "unprognostic (3.15e-1)" "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.46e-1)" "unprognostic (5.86e-2)" "unprognostic (9.09e-3)" "unprognostic (1.79e-1)" "unprognostic (8.84e-2)" "unprognostic (8.62e-3)" "unprognostic (1.28e-2)" "unprognostic (2.14e-1)" "unprognostic (1.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (2.81e-1)" "unprognostic (2.30e-1)" 3.4 2.5 2.1 2.8 2.3 3.8 3.1 4.3 2.6 3.9 2.0 3.3 3.3 3.6 2.3 3.1 3.5 1.9 2.8 2.0 2.1 2.3 2.8 2.6 4.0 2.4 2.2 4.5 3.5 3.9 3.0 3.0 2.3 3.3 2.1 2.0 4.6 3.3 5.1 5.2 3.1 2.4 1.6 3.6 3.1 3.5 2.4 4.2 2.8 4.0 3.6 3.5 3.4 3.4 7.8 24.8 7.1 6.4 8.0 7.7 6.2 8.9 8.2 9.2 10.1 13.0 5.5 12.6 6.3 9.5 4.2 5.7 7.7 9.7 5.7 7.5 9.2 12.6 12.0 12.5 7.5 8.1 7.8 7.6 7.7 9.2 9.6 5.7 5.8 6.7 12.3 7.8 5.9 10.8 8.2 5.2 4.7 6.8 8.7 9.4 8.7 5.7 4.2 14.0 7.3 6.4 10.2 10.1 7.2 5.4 4.1 14.4 7.8 11.3 7.7 4.8 11.2 9.3 5.9 8.5 7.5 7.8 9.5 1.8 3.6 1.4 4.5 3.6 6.9 4.7 3.5 4.1 2.8 4.4 4.2 5.3 0.7 3.4 5.3 4.2 3.9 3.3 2.1 2.3 4.3 2.6 2.0 2.1 2.4 2.2 2.3 1.6 2.4 3.4 3.0 22.4 33.3 2.0 6.9 5.5 4.4 2.8 4.0 7.4 3.1 2.4 3.2 0.0 17.1 3.7 14.6 8.0 3.2 5.7 3.9 4.1 5.8 1.7 4.0 7.1 13.8 9.5 1.4 3.0 8.3 7.4 4.6 2.3 25.2 4.9 3.6 2.6 4.6 6.7 1.5 4.2 2.0 6.8 1.8 6.3 7.2 7.0 0.0 1.9 5.8 4.1 11.3 1.0 1.4 2.9 2.8 3.0 6.1 4.6 7.8 2.8 9.2 9.6 0.0 5.7 3.6 9.9 10.1 1.9 5.1 10.3 6.7 3.7 5.7 2.6 ZNF703 "FLJ14299, NLZ1, ZEPPO1, ZNF503L, Zpo1" ENSG00000183779 "Zinc finger protein 703" Q9H7S9 8 37695782-37700019 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 108.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 434.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "intermediate monocyte: 3.3;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 12 "monocytes: 4.3" "Cell line enhanced" "Detected in many" "HEK 293: 156.8;OE19: 61.2;SK-MEL-30: 60.0;T-47d: 52.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023930, CAB068249" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB068249: AB_2665667, HPA023930: AB_1859425" "unprognostic (4.64e-2)" "unprognostic (3.15e-2)" "unprognostic (7.01e-3)" "unprognostic (1.71e-3)" "unprognostic (2.54e-1)" "unprognostic (1.42e-1)" "unprognostic (6.93e-2)" "unprognostic (4.23e-2)" "unprognostic (1.35e-1)" "unprognostic (1.84e-1)" "unprognostic (4.09e-1)" "unprognostic (9.63e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (5.63e-2)" "unprognostic (1.52e-1)" "unprognostic (1.01e-1)" "unprognostic (2.23e-1)" 24.6 14.4 16.6 7.6 15.0 1.9 27.4 10.7 16.9 39.9 9.8 46.9 15.1 27.8 12.7 18.2 33.2 6.2 18.8 14.2 10.3 8.1 4.2 10.7 4.1 21.8 17.9 19.6 8.7 1.9 5.9 12.1 16.4 21.7 12.6 0.4 18.3 8.7 108.4 57.4 25.9 11.6 15.0 18.9 22.8 2.9 14.7 2.8 10.6 33.3 2.9 36.8 28.7 10.7 3.2 6.6 0.8 5.2 15.1 7.9 5.2 29.1 13.6 8.8 7.4 27.2 36.0 0.0 7.2 18.4 4.0 17.2 3.0 4.4 6.8 0.8 156.8 0.0 9.5 17.5 14.9 0.0 3.0 26.6 8.2 9.1 3.7 19.0 7.8 0.3 0.4 0.0 14.1 27.4 0.1 0.8 2.6 61.2 11.6 2.7 4.7 3.7 2.7 14.2 2.9 0.2 5.4 4.6 60.0 6.2 52.6 3.1 23.1 10.3 23.7 16.1 12.3 1.9 0.1 0.2 9.1 3.2 6.7 0.0 0.4 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.1 16.6 15.0 10.7 16.9 14.2 10.3 21.8 17.9 16.4 15.0 14.7 10.7 11.9 6.4 0.0 14.7 15.3 48.2 13.2 28.9 103.0 3.7 39.3 27.8 9.1 2.8 14.5 5.5 0.0 41.4 7.7 52.0 3.9 7.1 0.4 30.8 37.0 9.5 79.6 0.0 1.5 2.5 37.2 36.0 14.8 20.3 0.0 5.8 2.5 2.2 36.2 0.0 2.8 95.4 10.2 23.6 31.9 0.7 31.4 31.2 33.8 11.2 7.9 9.3 0.0 0.0 0.6 3.7 56.9 15.8 1.9 9.7 35.4 2.8 7.7 0.9 52.6 54.9 66.4 0.0 0.6 99.7 74.6 434.1 6.0 6.1 92.6 10.7 ZNF831 "C20orf174, dJ492J12.1" ENSG00000124203 "Zinc finger protein 831" Q5JPB2 20 59123381-59259113 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;lymphoid tissue: 6.2" "Group enriched" "Detected in some" 4 "dendritic cells: 20.5;Excitatory neurons: 19.5;NK-cells: 17.5;Plasma cells: 9.5;T-cells: 31.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 1.2;T-cells: 2.1" "Group enriched" "Detected in some" 6 "Daudi: 4.0;HMC-1: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 25 "amygdala: 4.6;basal ganglia: 4.1;cerebral cortex: 3.4;hippocampal formation: 5.0;olfactory bulb: 5.4" HPA016839 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA016839: AB_1859466" "unprognostic (2.90e-3)" "unprognostic (7.70e-6)" "unprognostic (9.71e-4)" "unprognostic (1.31e-3)" "unprognostic (7.00e-2)" "unprognostic (3.00e-5)" "unprognostic (3.08e-3)" "unprognostic (2.23e-2)" "unprognostic (2.89e-3)" "unprognostic (2.21e-3)" "unprognostic (2.80e-3)" "unprognostic (4.31e-1)" "unprognostic (3.40e-3)" "unprognostic (2.39e-1)" "unprognostic (3.42e-2)" "unprognostic (2.21e-1)" "unprognostic (1.93e-2)" 0.3 0.1 2.2 2.3 1.6 0.9 0.3 0.0 2.7 0.1 0.0 0.3 0.2 0.1 0.2 0.2 0.2 0.5 0.0 3.4 0.3 0.1 0.2 0.6 6.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.1 1.9 0.0 0.0 2.6 0.6 0.2 0.9 1.5 0.3 0.0 3.8 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.8 0.0 1.4 0.2 1.0 1.5 0.0 0.1 0.8 1.0 0.1 1.2 0.0 0.0 2.1 0.4 2.2 1.6 0.0 2.7 3.4 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.3 0.0 0.6 0.7 4.8 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.7 0.0 0.0 1.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 19.5 0.0 0.0 0.1 0.5 0.1 2.5 0.0 0.7 0.0 0.0 0.0 2.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 17.5 0.5 0.9 0.0 0.0 0.0 9.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.5 0.5 0.0 0.0 0.0 31.2 0.0 0.0 0.0 ZNF843 MGC46336 ENSG00000176723 "Zinc finger protein 843" Q8N446 16 31432593-31443160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 4.6;Cardiomyocytes: 5.3;Prostatic glandular cells: 3.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 2.3;EFO-21: 1.8;HMC-1: 1.6" "HPA030911, HPA030912, HPA077945" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nuclear speckles" "HPA030911: AB_2673656, HPA030912: AB_10670434, HPA077945: " "unprognostic (9.27e-2)" "unprognostic (1.32e-1)" "unprognostic (3.43e-3)" "unprognostic (9.24e-2)" "unprognostic (1.33e-1)" "unprognostic (6.25e-3)" "unprognostic (2.86e-1)" "unprognostic (8.30e-3)" "unprognostic (3.55e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-3)" "unprognostic (2.93e-3)" "unprognostic (5.96e-3)" "unprognostic (1.23e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-5)" "unprognostic (1.17e-1)" 0.6 0.5 1.5 0.3 1.2 0.3 0.6 2.5 1.3 1.0 0.0 0.4 0.2 1.0 0.7 0.4 1.1 0.7 1.7 1.6 1.9 0.6 0.4 0.3 0.3 1.1 1.4 3.0 2.1 0.9 1.5 0.4 0.9 0.6 0.1 1.1 1.5 0.8 2.2 0.9 0.3 0.5 1.1 0.4 0.4 0.5 1.8 0.2 1.0 0.8 0.2 0.5 0.6 0.9 0.1 0.3 0.2 1.2 2.3 0.6 0.0 0.2 0.2 0.0 0.1 0.1 0.3 0.0 1.8 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.6 0.2 1.6 1.2 0.3 0.0 0.1 0.8 0.0 0.2 0.2 0.2 0.6 0.8 0.1 0.4 0.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.7 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.2 0.8 0.0 0.2 0.1 0.1 0.0 0.1 0.4 1.0 0.2 0.2 0.7 0.1 0.4 0.2 0.2 0.7 0.1 0.2 0.1 0.4 0.7 1.7 0.1 0.2 0.1 1.0 1.5 1.2 2.5 1.3 1.6 1.9 1.1 1.4 0.9 1.1 1.8 0.9 0.5 0.0 0.5 2.9 0.3 0.8 4.6 0.1 0.0 2.2 0.9 1.3 5.3 0.0 0.7 0.0 2.1 0.3 0.1 0.3 0.0 0.3 0.2 0.4 2.0 1.0 1.2 0.0 1.4 0.2 0.1 1.4 0.0 0.4 1.3 1.4 1.8 0.3 0.6 0.0 1.7 0.0 0.0 0.3 2.1 0.0 1.5 0.9 0.0 0.0 0.1 1.4 2.1 1.0 1.3 0.1 0.1 1.5 0.1 3.6 0.0 0.4 0.0 1.9 0.0 2.8 1.3 0.4 0.7 0.1 1.4 0.3 1.2 0.8 0.1 1.9 ZNF853 DKFZp434J1015 ENSG00000236609 "Zinc finger protein 853" P0CG23 7 6615610-6624290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.2;Granulosa cells: 15.1;Muller glia cells: 13.2;Sertoli cells: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 20.1;SH-SY5Y: 29.5;U-2 OS: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA067690 Approved Approved Nucleoli NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoli "HPA067690: AB_2685888" "unprognostic (1.35e-3)" "unprognostic (2.63e-1)" "unprognostic (7.17e-2)" "unprognostic (8.77e-2)" "unprognostic (2.76e-1)" "unprognostic (1.96e-1)" "unprognostic (1.17e-1)" "unprognostic (3.54e-1)" "unprognostic (2.26e-2)" "unprognostic (5.06e-2)" "unprognostic (1.87e-3)" "unprognostic (9.28e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.41e-3)" "unprognostic (4.95e-2)" "unprognostic (2.30e-3)" "unprognostic (4.01e-2)" 4.1 2.8 24.8 2.3 24.7 0.6 4.5 20.4 24.0 9.6 11.8 12.9 1.1 11.3 4.4 4.3 9.2 4.5 10.5 23.7 23.7 4.9 0.5 3.7 2.9 27.8 27.9 12.0 7.0 5.5 6.6 2.8 25.1 7.8 1.7 5.1 5.4 8.6 27.1 3.1 4.4 6.6 25.6 3.5 4.9 2.6 24.8 3.3 7.9 20.2 2.0 10.1 4.9 21.0 0.0 1.6 4.7 20.1 0.2 0.0 0.2 0.4 0.0 2.1 0.4 3.6 0.8 0.0 7.8 0.0 0.7 0.0 7.2 0.2 2.0 0.0 2.6 0.6 0.0 3.8 2.8 0.0 0.1 0.7 0.6 0.2 0.1 2.0 0.0 1.6 3.2 0.1 1.3 0.1 0.5 2.7 7.5 0.0 0.0 2.3 7.8 0.1 1.5 7.6 6.3 29.5 0.0 0.3 1.2 3.9 1.1 4.3 0.0 1.5 19.5 0.0 1.9 0.4 0.1 0.1 0.0 0.0 7.8 0.0 0.0 0.8 0.2 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 24.8 24.7 20.4 24.0 23.7 23.7 27.8 27.9 25.1 25.6 24.8 21.0 4.3 0.0 0.0 2.0 1.0 0.5 1.5 0.2 1.2 13.2 3.2 4.4 10.4 0.0 0.6 7.3 6.2 0.0 2.0 0.1 0.0 0.6 1.6 7.5 4.3 3.2 1.8 0.4 1.5 0.7 0.0 4.4 0.5 2.3 0.0 15.1 2.5 0.0 0.1 5.0 2.7 0.0 0.0 0.0 0.9 2.4 5.3 0.2 3.6 1.9 0.1 13.2 1.0 2.0 2.8 0.4 0.1 8.6 1.3 3.3 0.0 0.2 2.3 10.4 13.1 6.4 5.4 0.5 0.5 0.4 0.3 0.3 1.8 6.9 0.1 0.7 ZNRF1 "DKFZp434E229, FLJ14846, nin283" ENSG00000186187 "Zinc and ring finger 1" Q8ND25 16 74999024-75110994 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.4;T-reg: 2.4" "Group enriched" "Detected in many" 4 "granulocytes: 2.4;T-cells: 2.4" "Cell line enhanced" "Detected in all" "HMC-1: 176.9;MOLT-4: 134.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027470 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA027470: AB_10603108" "unprognostic (2.78e-2)" "prognostic favorable (9.90e-4)" "unprognostic (4.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.34e-2)" "unprognostic (1.18e-2)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-2)" "unprognostic (5.38e-2)" "unprognostic (3.69e-1)" "unprognostic (2.28e-1)" "unprognostic (1.46e-1)" "unprognostic (4.89e-2)" "unprognostic (2.87e-1)" "unprognostic (2.10e-2)" "unprognostic (1.44e-2)" 18.7 16.5 21.1 9.6 22.3 6.7 17.8 9.1 22.8 25.3 19.0 30.6 9.6 22.5 9.5 65.9 18.0 7.5 21.0 23.4 24.5 14.7 17.6 24.1 7.7 19.6 22.5 17.4 11.5 11.8 13.4 11.2 18.6 13.7 12.1 7.4 16.9 7.0 81.2 25.0 15.3 11.4 13.4 4.5 21.0 37.4 30.7 53.2 29.3 30.6 13.3 22.5 26.4 17.5 10.9 15.7 26.7 27.5 27.7 21.4 91.2 13.0 18.3 17.5 17.1 25.4 33.2 2.9 9.9 28.3 16.8 25.5 13.0 17.8 13.9 26.7 7.5 56.7 4.8 47.0 22.0 27.5 176.9 19.5 14.7 18.4 14.9 30.8 29.0 68.3 27.8 8.8 13.7 104.5 134.6 100.6 37.1 31.4 16.7 59.0 10.0 17.4 25.1 30.5 35.4 37.7 20.7 27.0 8.3 21.7 71.6 25.8 19.9 12.0 21.0 21.5 7.9 50.5 55.1 31.6 15.8 30.2 12.6 2.4 0.5 0.4 0.0 0.5 0.5 0.0 0.6 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.5 0.0 2.4 0.1 21.1 22.3 9.1 22.8 23.4 24.5 19.6 22.5 18.6 13.4 30.7 17.5 34.8 9.6 14.4 16.6 1.8 15.9 16.0 11.2 4.6 12.6 24.3 22.4 16.4 18.6 14.0 3.7 52.1 6.4 2.3 25.5 0.0 8.9 25.9 30.7 15.1 30.2 19.8 30.5 45.2 12.7 10.1 15.1 18.3 28.0 36.8 23.7 12.8 14.4 10.4 3.3 42.4 14.0 14.2 7.3 10.9 16.3 6.8 7.3 14.2 33.7 7.6 15.0 0.0 33.7 29.5 20.0 12.1 4.1 1.8 17.2 9.6 6.2 15.1 6.5 0.0 12.4 14.7 13.6 18.7 21.0 19.6 4.5 13.3 16.7 12.7 29.6 ZW10 KNTC1AP ENSG00000086827 "Zw10 kinetochore protein" O43264 11 113733187-113773735 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, ER-Golgi transport, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 44.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011565, HPA051253, HPA055410" Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Endoplasmic reticulum, Cytosol" "CAB011565: AB_779030, HPA051253: AB_2681408, HPA055410: AB_2682809" "unprognostic (4.33e-3)" "unprognostic (6.65e-2)" "prognostic favorable (2.70e-4)" "unprognostic (3.12e-1)" "unprognostic (5.51e-2)" "unprognostic (6.52e-2)" "prognostic unfavorable (8.57e-4)" "unprognostic (7.44e-2)" "unprognostic (8.01e-3)" "unprognostic (5.91e-2)" "unprognostic (1.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.57e-3)" "unprognostic (6.00e-2)" "unprognostic (8.73e-2)" "unprognostic (2.95e-1)" "unprognostic (1.17e-3)" 6.9 6.0 3.5 8.1 4.1 9.2 10.9 5.0 4.8 8.1 3.7 8.3 7.2 7.6 7.3 9.6 6.1 5.9 5.6 3.8 3.8 8.8 13.0 6.4 9.4 4.2 4.7 6.9 9.1 7.2 5.1 7.7 4.6 7.9 10.0 6.8 8.3 7.3 13.4 13.7 7.1 8.7 3.8 7.0 7.3 13.5 4.2 12.1 6.7 12.0 12.0 8.5 7.5 5.7 25.0 14.4 30.2 22.1 18.4 20.0 17.4 26.1 21.4 32.2 32.5 38.1 46.1 29.0 34.5 25.8 28.1 34.2 36.7 31.6 46.0 19.1 15.1 30.9 12.0 23.5 20.6 31.7 18.8 16.5 20.8 34.1 27.4 14.2 33.5 31.7 36.3 11.8 33.8 12.2 29.3 20.9 21.7 29.8 29.0 27.0 34.4 32.7 21.2 22.2 13.3 15.7 29.1 24.2 11.8 24.2 44.9 17.4 21.1 28.8 44.2 14.4 28.8 6.1 10.6 30.6 9.9 38.1 33.0 8.5 7.4 7.4 6.3 10.4 8.5 5.9 5.9 5.6 9.5 5.1 5.4 6.8 1.9 6.2 9.2 3.0 5.6 5.6 3.5 4.1 5.0 4.8 3.8 3.8 4.2 4.7 4.6 3.8 4.2 5.7 5.6 0.0 4.8 11.1 5.8 12.1 7.6 7.5 8.0 2.9 5.9 5.0 6.8 7.2 7.3 0.0 0.0 9.2 3.9 3.9 9.8 10.1 10.7 7.7 7.1 6.9 3.6 10.7 12.5 11.8 10.0 6.5 8.2 12.7 3.8 7.8 3.9 8.1 9.2 3.3 11.1 4.6 4.1 6.0 5.4 7.3 5.0 6.1 3.6 10.3 8.0 7.6 3.1 12.1 18.7 8.4 3.8 5.7 10.4 5.6 5.3 7.2 4.8 4.9 19.7 7.0 7.0 44.4 17.5 9.4 12.5 10.5 5.9 6.9 6.4 5.8