Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AADACL2 MGC72001 ENSG00000197953 "Arylacetamide deacetylase like 2" Q6P093 3 151733916-151761339 "Predicted secreted proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "skin 1: 35.6" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 30.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.20e-2)" "unprognostic (3.10e-3)" "unprognostic (2.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (3.00e-1)" "unprognostic (2.91e-4)" 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 35.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 30.7 0.1 0.1 0.0 0.0 0.0 AADACL3 ENSG00000188984 "Arylacetamide deacetylase like 3" Q5VUY0 1 12716110-12728760 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "placenta: 1.6;skin 1: 1.2" "Cell type enhanced" "Detected in single" "Extravillous trophoblasts: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.01e-1)" "unprognostic (2.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AADACL4 ENSG00000204518 "Arylacetamide deacetylase like 4" Q5VUY2 1 12644085-12667076 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.20e-1)" "unprognostic (1.89e-2)" 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AAMDC "C11orf67, CK067, FLJ21035, PTD015" ENSG00000087884 "Adipogenesis associated Mth938 domain containing" Q9H7C9 11 77821109-77918432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 656.7" "Cell type enhanced" "Detected in all" "Theca cells: 385.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 143.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 280.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA037918, HPA037919" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA037918: AB_2675737, HPA037919: AB_2675738" "unprognostic (3.10e-2)" "unprognostic (9.04e-3)" "unprognostic (6.02e-2)" "unprognostic (4.67e-1)" "unprognostic (1.27e-1)" "unprognostic (3.51e-2)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.07e-2)" "unprognostic (1.23e-1)" "unprognostic (7.08e-2)" "unprognostic (1.90e-1)" "unprognostic (2.08e-1)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "unprognostic (3.84e-2)" 75.8 180.9 30.1 13.0 35.8 21.0 62.5 35.2 42.6 51.0 31.4 66.6 37.4 41.4 27.9 24.6 47.5 23.4 178.9 30.5 31.7 56.0 57.9 46.9 13.8 37.2 34.4 56.7 34.4 27.4 28.6 21.7 35.9 46.0 29.2 20.1 36.6 34.6 656.7 55.4 47.5 40.2 31.9 31.7 62.4 42.2 34.3 23.7 42.2 173.0 13.6 48.1 42.7 42.7 30.3 24.3 37.2 26.5 106.0 73.3 10.0 49.2 33.4 43.8 54.1 280.1 44.6 20.3 46.5 83.0 43.2 16.9 56.4 32.9 51.9 47.1 45.3 19.5 43.5 52.4 52.2 11.2 17.1 98.3 22.2 46.0 24.2 40.2 131.3 27.0 23.1 32.0 93.2 35.6 23.8 44.3 17.3 84.5 41.4 22.3 63.6 19.6 58.2 18.1 13.1 49.2 62.4 26.7 36.0 55.1 41.2 21.1 138.2 45.5 24.7 87.5 16.5 34.2 58.4 37.8 17.7 18.0 26.2 143.1 28.9 33.3 14.6 17.7 18.8 18.3 28.4 24.2 32.6 25.2 24.8 18.4 16.9 35.9 17.5 33.8 47.3 16.3 30.1 35.8 35.2 42.6 30.5 31.7 37.2 34.4 35.9 31.9 34.3 42.7 68.4 83.3 25.4 19.6 10.0 64.2 82.7 51.0 24.5 10.0 58.7 67.2 114.1 62.9 42.5 79.1 4.2 29.1 11.8 70.2 144.8 60.0 100.1 37.7 27.8 55.7 22.7 19.1 6.9 73.1 43.1 64.5 39.3 35.8 41.2 53.4 93.9 122.2 46.9 11.8 8.9 48.7 44.7 29.9 35.9 36.3 68.3 22.5 83.6 8.4 56.2 101.3 16.5 18.1 24.8 70.2 132.2 64.3 10.2 46.6 160.3 200.8 50.1 13.9 46.0 53.5 65.8 154.0 85.4 29.2 100.7 15.7 14.8 385.5 61.0 71.2 AARD "C8orf85, LOC441376" ENSG00000205002 "Alanine and arginine rich domain containing protein" Q4LEZ3 8 116938207-116944487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.5;urinary bladder: 7.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 27.6;Breast glandular cells: 26.0;Breast myoepithelial cells: 29.0;granulocytes: 14.5;Late spermatids: 18.4;Proximal tubular cells: 14.9;Spermatocytes: 57.4" "Cancer enriched" "Detected in many" 8 "breast cancer: 27.0" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 21.7;JURKAT: 7.2;SK-BR-3: 11.8;U-2 OS: 5.5;U-266/84: 4.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 4 "midbrain: 4.4" HPA068290 Approved "Lipid droplets" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Lipid droplets" "HPA068290: " "unprognostic (5.81e-2)" "unprognostic (2.28e-1)" "unprognostic (1.32e-1)" "unprognostic (7.28e-8)" "unprognostic (3.42e-2)" "unprognostic (4.32e-3)" "unprognostic (4.34e-2)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (8.29e-2)" "unprognostic (8.57e-3)" "unprognostic (4.20e-1)" "unprognostic (2.23e-6)" "unprognostic (1.67e-1)" "unprognostic (9.78e-3)" "unprognostic (3.77e-2)" "unprognostic (5.27e-4)" 0.6 0.9 0.5 0.4 0.8 0.2 4.3 0.4 0.9 0.3 0.9 5.9 0.1 0.8 0.2 2.4 0.1 0.2 0.0 0.6 0.6 1.0 0.0 2.5 0.8 1.2 1.0 0.0 0.0 0.0 0.0 0.4 0.9 0.6 0.5 0.1 2.0 0.1 0.1 1.5 1.0 1.0 0.8 0.1 6.8 22.5 0.7 0.0 0.1 0.0 0.4 7.7 0.2 1.3 0.0 0.0 0.5 0.0 0.0 0.0 0.2 1.8 0.3 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.5 0.0 0.2 0.1 2.4 0.0 0.2 0.4 0.0 0.1 0.1 0.1 0.0 7.2 0.0 2.4 0.1 0.5 0.9 0.1 1.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 1.9 0.3 0.0 11.8 0.1 0.2 0.5 0.0 0.0 0.1 5.5 0.2 0.0 1.6 4.5 0.0 3.0 0.0 0.3 1.2 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.7 0.3 0.1 0.2 0.6 0.0 0.5 0.8 0.4 0.9 0.6 0.6 1.2 1.0 0.9 0.8 0.7 1.3 0.2 12.8 27.6 0.0 0.1 0.8 0.6 0.2 0.0 0.4 26.0 29.0 0.9 0.0 5.0 7.3 0.0 0.2 0.8 0.1 1.9 0.1 9.3 0.1 1.7 0.9 0.0 0.0 0.8 0.0 0.9 1.4 0.0 0.0 14.5 0.1 0.0 0.1 0.0 1.7 2.1 0.0 0.0 0.0 0.3 18.4 4.1 0.5 0.0 0.0 0.1 0.1 4.1 0.0 0.2 0.1 0.0 0.7 0.0 0.6 0.0 14.9 0.7 0.2 0.0 0.5 1.1 57.4 7.3 0.0 0.6 0.3 0.8 2.0 0.0 0.4 ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 12.9;Suprabasal keratinocytes: 38.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "hTCEpi: 38.7;SK-BR-3: 18.3;T-47d: 9.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 5.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.3 0.2 0.2 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 2.8 0.3 3.9 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 38.7 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.5 0.1 2.7 0.0 18.3 0.0 0.2 9.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 12.9 0.9 6.0 0.0 0.2 1.0 0.5 0.5 0.0 5.1 0.0 0.0 1.1 0.0 3.0 0.0 0.1 2.2 2.6 0.3 0.1 0.0 0.0 1.4 0.0 2.7 0.1 1.5 3.7 0.0 0.5 0.0 0.0 0.4 1.7 2.9 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.6 1.9 0.0 0.7 0.0 1.0 0.0 0.1 3.1 0.2 0.0 0.0 0.2 0.7 0.4 2.2 38.6 3.4 0.0 0.1 0.9 2.7 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ABCC11 MRP8 ENSG00000121270 "ATP binding cassette subfamily C member 11" Q96J66 16 48165773-48247568 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "breast: 46.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Breast glandular cells: 4.4;Early spermatids: 3.3;Hepatocytes: 2.5;Late spermatids: 1.9;Spermatocytes: 4.0" "Cancer enriched" "Detected in some" 4 "breast cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 67.1" "Not detected" "Not detected" NA NA "Cluster 37: B-cells - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.35e-1)" "unprognostic (3.47e-2)" "unprognostic (3.87e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (6.03e-2)" "unprognostic (3.87e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-2)" "unprognostic (2.39e-1)" "unprognostic (2.64e-1)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (2.21e-2)" "unprognostic (1.58e-1)" "unprognostic (1.13e-2)" "unprognostic (5.54e-4)" 0.1 0.0 0.2 0.0 0.3 0.1 46.4 0.4 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.5 0.1 0.0 0.2 0.2 0.0 1.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 2.4 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 16.0 0.1 0.0 67.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.5 3.3 0.2 0.0 0.0 0.0 0.0 0.4 4.4 0.9 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.3 0.3 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.3 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 4.0 0.4 0.5 0.0 0.3 0.2 0.1 0.0 0.1 ABCC12 MRP9 ENSG00000140798 "ATP binding cassette subfamily C member 12" Q96J65 16 48081006-48156018 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.9" "Group enriched" "Detected in some" 4 "Early spermatids: 4.4;Excitatory neurons: 5.1;Late spermatids: 2.2;Spermatocytes: 6.0;Theca cells: 3.1" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA043100 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA043100: AB_10794922" "unprognostic (1.53e-1)" "unprognostic (6.87e-2)" "unprognostic (2.37e-2)" "unprognostic (4.62e-3)" "unprognostic (1.88e-1)" "unprognostic (1.59e-2)" "unprognostic (2.65e-1)" "unprognostic (7.53e-2)" "unprognostic (4.23e-1)" 0.0 0.0 0.3 0.0 0.3 0.0 0.3 0.3 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.4 0.4 0.2 0.2 0.2 0.2 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.0 0.9 0.0 0.0 0.0 0.0 3.1 0.0 0.0 ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 31.5;Distal tubular cells: 45.0;Hepatocytes: 77.9;Proximal enterocytes: 33.7;Proximal tubular cells: 151.1" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 7 "monocytes: 3.4" "Cell line enriched" "Detected in some" 8 "Hep G2: 68.4" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" 5.6 3.6 0.7 0.3 0.7 0.7 3.8 0.7 1.1 1.0 0.8 5.7 13.2 0.3 0.6 0.3 1.5 2.9 2.6 0.7 0.7 27.4 134.2 7.4 0.0 0.8 0.9 1.0 17.2 2.1 0.9 0.2 0.8 2.9 2.8 0.3 12.7 1.0 4.6 0.4 7.9 0.3 0.7 0.7 6.4 0.4 0.8 0.0 5.6 0.1 0.0 0.4 0.7 0.7 0.0 1.5 0.7 0.0 0.0 0.8 1.8 0.0 0.4 1.0 1.6 7.1 2.3 0.0 0.8 0.0 0.2 0.0 0.7 0.1 0.6 0.0 0.7 1.8 0.2 68.4 0.4 0.0 0.0 2.7 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.0 2.3 0.0 0.1 1.0 0.0 0.8 0.1 0.3 8.4 5.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.7 0.7 0.7 1.1 0.7 0.7 0.8 0.9 0.8 0.7 0.8 0.7 0.3 28.9 31.5 2.9 1.9 0.1 0.5 3.2 0.0 1.0 4.3 3.6 3.3 18.6 8.7 9.2 0.0 0.0 0.0 13.7 45.0 2.2 0.5 4.8 1.0 0.8 3.0 2.7 1.0 7.9 0.0 1.7 13.3 1.0 1.3 1.9 1.8 77.9 1.0 0.0 1.1 10.9 0.0 3.5 0.0 0.7 1.5 1.8 1.8 3.7 3.1 1.5 0.0 1.0 0.4 2.2 8.1 5.7 0.3 2.0 33.7 151.1 25.4 0.6 0.0 0.3 1.2 0.4 0.3 0.2 0.9 0.0 1.4 1.8 11.9 0.7 ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12, lysophospholipase" Q8N2K0 20 25294742-25390835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease variant, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 315.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA026866: AB_1844446" "prognostic unfavorable (3.81e-5)" "prognostic favorable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" 29.5 33.0 55.7 27.4 67.3 26.5 26.9 70.0 64.7 32.1 35.9 37.0 47.0 25.3 133.1 50.0 24.8 33.4 30.5 77.3 58.2 45.5 29.8 32.6 30.8 70.9 64.6 30.6 117.8 55.3 42.1 29.6 73.3 35.5 36.4 30.8 36.9 39.9 13.3 52.4 52.8 23.6 66.0 22.0 55.0 19.2 71.8 23.4 80.8 14.8 41.5 37.2 35.1 96.9 67.2 148.3 41.6 50.9 79.6 47.1 93.3 97.0 84.5 73.7 84.6 90.1 93.0 21.8 53.3 77.0 155.1 116.5 44.4 56.8 62.8 22.7 41.9 33.3 46.8 128.4 59.3 33.3 71.6 58.7 42.0 85.4 44.1 95.7 33.2 37.8 25.8 315.3 72.8 142.5 51.8 31.0 29.4 77.8 96.8 39.2 95.3 195.0 43.4 145.7 46.6 39.7 75.4 198.9 133.8 72.3 67.4 47.6 44.6 98.3 63.0 57.1 54.0 38.8 36.1 33.4 61.8 38.7 57.3 15.8 18.8 17.3 9.9 17.0 7.5 3.8 10.2 13.7 17.9 5.1 8.9 8.9 3.6 15.4 17.7 17.0 10.4 8.6 55.7 67.3 70.0 64.7 77.3 58.2 70.9 64.6 73.3 66.0 71.8 96.9 20.7 6.4 6.5 19.2 13.8 17.7 32.0 9.8 19.4 34.5 19.6 19.7 16.6 30.0 13.7 27.6 10.4 91.6 22.2 97.0 27.4 33.7 53.0 24.9 18.1 17.5 34.0 14.5 37.7 34.3 95.2 22.9 35.2 28.3 10.2 26.9 15.0 19.5 114.1 42.1 46.0 28.9 20.3 37.8 43.8 107.1 16.1 62.4 33.8 42.2 58.7 44.1 23.7 50.8 67.5 22.9 77.7 20.7 39.3 31.6 126.7 24.6 13.1 23.3 26.3 13.8 19.5 19.9 37.7 27.2 18.3 130.8 18.0 19.6 33.3 35.2 ABHD12B "BEM46L3, C14orf29" ENSG00000131969 "Abhydrolase domain containing 12B" Q7Z5M8 14 50872053-50904970 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 6.8;retina: 15.6;skin 1: 10.5" "Cell type enriched" "Detected in some" 7 "Muller glia cells: 188.1" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 1.0;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "thalamus: 2.1" "Low region specificity" "Detected in many" HPA002873 Uncertain Uncertain Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA002873: AB_2220573" "unprognostic (6.61e-2)" "unprognostic (3.49e-2)" "unprognostic (2.92e-3)" "unprognostic (1.99e-3)" "unprognostic (4.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.62e-2)" "unprognostic (2.09e-1)" "unprognostic (4.31e-2)" "unprognostic (6.27e-2)" "unprognostic (3.30e-1)" "unprognostic (3.35e-1)" "unprognostic (1.70e-3)" "unprognostic (3.16e-2)" "unprognostic (9.62e-2)" "unprognostic (3.18e-3)" "unprognostic (1.68e-1)" 0.5 0.0 2.7 0.1 6.5 1.6 1.3 0.0 2.6 0.0 0.9 0.7 0.0 0.3 0.0 0.2 1.0 0.1 0.1 1.4 1.7 0.2 0.0 0.3 0.1 0.2 5.0 0.0 0.0 0.2 0.1 0.1 1.4 0.0 1.0 15.6 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.6 6.8 0.3 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.7 6.5 0.0 2.6 1.4 1.7 0.2 5.0 1.4 0.0 6.8 1.0 2.4 0.0 0.0 0.3 0.1 0.4 0.1 1.5 0.0 3.4 0.1 0.1 1.9 0.0 5.0 1.8 2.1 0.1 0.0 2.2 0.0 0.0 7.7 2.5 0.2 0.7 0.0 0.0 9.9 0.0 0.0 0.7 0.0 0.6 1.3 0.0 0.0 0.0 0.1 0.0 0.7 1.0 4.1 0.0 0.0 5.8 1.2 0.1 0.0 0.0 0.0 188.1 0.0 1.0 4.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 26.4 18.1 0.0 0.1 1.2 0.3 0.2 0.0 1.4 0.3 0.1 0.0 1.8 0.2 ABHD6 ENSG00000163686 "Abhydrolase domain containing 6, acylglycerol lipase" Q9BV23 3 58237532-58295693 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 64.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 60.6;Oligodendrocytes: 88.6;Proximal enterocytes: 55.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017283, HPA073225" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 3: HMC-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles Nucleoplasm "HPA017283: AB_1844452, HPA073225: AB_2686583" "unprognostic (4.20e-2)" "unprognostic (7.92e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.35e-2)" "unprognostic (1.16e-2)" "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (1.15e-2)" "unprognostic (9.54e-2)" "unprognostic (1.11e-3)" "unprognostic (1.34e-2)" "unprognostic (1.94e-1)" "prognostic favorable (1.11e-11)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (2.72e-1)" "unprognostic (6.31e-2)" 12.2 12.9 24.0 6.4 33.9 0.9 8.9 34.1 32.4 4.4 19.4 12.7 39.5 6.1 14.7 6.4 9.1 5.8 5.7 31.6 26.9 35.6 64.9 8.5 8.0 31.7 32.3 5.0 2.7 8.9 16.6 6.4 31.7 5.5 11.1 9.2 4.0 14.3 4.6 25.5 52.3 9.2 28.8 35.0 12.9 3.9 35.5 5.5 9.1 5.4 7.6 5.8 5.9 49.8 3.5 12.0 1.8 8.5 23.2 4.2 21.2 8.9 8.1 9.2 12.5 6.9 4.8 6.6 0.8 4.7 28.5 9.9 8.3 3.9 8.4 11.3 4.2 5.7 8.1 9.7 7.8 1.7 28.1 3.9 18.4 8.8 3.8 10.6 5.0 10.6 6.8 15.0 7.2 2.6 11.7 0.7 6.1 28.5 27.3 4.2 3.8 14.8 14.5 4.8 10.8 4.4 9.9 5.1 19.0 3.7 3.6 4.5 5.8 6.6 7.0 16.6 10.8 4.2 13.5 0.3 17.1 16.9 9.3 0.0 2.2 1.7 1.6 7.4 1.5 3.6 0.9 1.9 3.7 2.5 0.9 1.1 0.0 0.7 5.2 5.4 1.2 1.0 24.0 33.9 34.1 32.4 31.6 26.9 31.7 32.3 31.7 28.8 35.5 49.8 27.1 0.0 1.8 11.4 13.6 8.7 3.0 2.7 6.2 13.3 2.1 1.5 5.6 5.7 4.9 3.7 4.2 2.0 7.7 11.2 1.9 3.0 1.0 9.8 7.9 14.1 0.0 5.7 33.6 1.9 0.9 2.9 7.7 1.5 11.4 10.1 21.4 60.6 8.9 15.2 34.3 4.0 0.0 16.7 20.0 0.7 6.8 12.1 3.6 11.2 11.5 11.2 6.2 37.7 88.6 1.9 1.4 8.2 2.0 1.8 55.1 17.4 13.8 3.3 0.0 2.9 3.9 0.5 2.2 6.9 24.6 0.5 5.1 16.0 5.8 2.0 ABHD8 "FLJ11743, MGC14280, MGC2512" ENSG00000127220 "Abhydrolase domain containing 8" Q96I13 19 17292131-17310236 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 57.8" "Cell type enhanced" "Detected in many" "Early spermatids: 146.2;Horizontal cells: 72.3;Late spermatids: 314.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 53.9;U-266/70: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037658, HPA058209" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA037658: AB_10672602, HPA058209: AB_2683638" "unprognostic (4.71e-3)" "unprognostic (5.06e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (7.45e-3)" "unprognostic (7.09e-2)" "unprognostic (1.96e-2)" "unprognostic (5.61e-2)" "unprognostic (9.62e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.04e-5)" "unprognostic (3.77e-1)" "unprognostic (6.36e-3)" "unprognostic (1.56e-1)" "unprognostic (3.14e-1)" "unprognostic (1.50e-1)" "unprognostic (9.24e-2)" 7.4 26.0 32.3 3.9 37.2 4.5 8.8 20.6 57.8 12.0 14.3 16.7 2.7 11.5 1.7 5.7 11.2 2.9 12.4 36.3 23.8 11.6 28.2 9.6 4.5 19.2 26.5 14.2 11.6 8.9 24.6 5.6 19.5 14.6 0.6 6.1 10.5 6.7 13.8 11.3 7.8 2.7 16.1 11.4 11.1 45.7 30.0 4.7 12.1 3.9 2.2 10.2 8.8 27.0 22.5 6.4 3.2 12.6 4.1 1.4 34.2 4.5 6.0 4.8 6.1 5.6 15.0 1.6 6.1 3.5 7.4 3.1 3.2 7.8 1.0 26.6 21.1 7.3 9.6 9.7 13.4 0.5 9.9 3.8 4.7 8.2 1.0 7.4 3.5 12.5 6.6 12.4 1.9 1.2 9.0 1.3 6.0 3.8 53.9 13.3 9.9 6.5 4.3 2.1 3.9 21.3 10.0 3.3 14.6 2.8 13.6 12.6 2.1 4.4 9.6 22.7 8.1 40.6 33.0 7.9 14.9 8.7 4.1 0.0 2.4 3.0 1.1 1.9 0.7 0.3 1.6 0.9 2.9 0.5 1.3 1.2 1.3 1.7 1.9 1.3 1.2 1.0 32.3 37.2 20.6 57.8 36.3 23.8 19.2 26.5 19.5 16.1 30.0 27.0 5.9 0.0 1.3 20.9 5.0 3.8 4.7 8.0 8.6 56.9 9.6 14.4 2.0 7.2 4.8 7.3 18.8 20.6 4.0 0.8 7.9 13.1 146.2 3.0 3.7 4.3 7.2 0.8 22.7 8.5 9.0 7.7 2.6 2.5 4.5 12.3 4.2 13.5 22.5 72.3 19.4 3.3 12.2 8.1 6.9 314.2 12.5 11.1 1.8 8.4 18.4 36.1 7.2 2.5 1.4 8.4 4.3 25.6 9.2 6.3 0.4 9.7 1.7 38.2 6.6 13.6 5.6 64.3 1.5 3.0 4.1 24.8 4.8 10.8 1.3 4.3 ABRACL "C6orf115, Costars, HSPC280, PRO2013" ENSG00000146386 "ABRA C-terminal like" Q9P1F3 6 139028745-139043302 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 440.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 501.5;NB-4: 530.8;U-937: 515.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030217 Enhanced Approved Nucleoplasm,Cytosol NA NA 9200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA030217: AB_10602335" "unprognostic (1.10e-2)" "unprognostic (1.63e-1)" "unprognostic (9.30e-2)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (1.72e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.50e-1)" "unprognostic (2.21e-1)" "unprognostic (8.17e-2)" "unprognostic (2.16e-1)" "unprognostic (3.07e-3)" "unprognostic (5.90e-3)" "unprognostic (3.63e-2)" "unprognostic (3.29e-2)" "prognostic favorable (1.65e-6)" 20.1 9.6 16.8 73.7 16.2 87.7 44.9 13.5 20.8 20.7 14.7 95.0 74.1 22.0 136.0 42.0 12.4 36.0 13.3 18.6 15.7 50.0 60.7 31.2 123.1 14.7 14.6 4.1 16.1 49.1 14.4 29.1 16.2 16.3 86.5 5.4 40.8 12.2 3.0 38.8 74.4 23.5 14.9 73.9 34.4 32.3 16.4 139.6 42.4 7.5 87.9 79.6 17.1 16.0 76.8 40.7 100.7 94.8 39.7 62.2 110.6 59.7 42.9 44.5 91.2 91.2 87.4 0.4 105.8 59.8 189.5 112.9 90.4 130.0 51.9 204.4 167.4 297.8 20.7 31.6 57.6 501.5 130.5 55.9 108.2 59.9 49.1 79.4 237.5 204.9 38.4 100.4 129.5 162.7 314.2 530.8 120.9 119.1 78.5 199.8 62.3 23.8 121.7 225.0 225.4 24.8 40.5 112.3 194.5 141.9 45.1 369.8 175.7 28.2 24.0 58.9 107.7 54.1 169.2 20.9 35.7 515.5 84.2 232.3 178.0 114.2 161.1 334.3 252.2 93.8 259.3 208.2 193.9 96.9 250.9 235.9 48.8 152.1 514.5 215.9 260.2 347.8 16.8 16.2 13.5 20.8 18.6 15.7 14.7 14.6 16.2 14.9 16.4 16.0 54.2 19.2 22.2 2.0 87.1 139.6 71.4 195.2 108.1 0.3 86.6 67.8 3.8 27.1 126.2 44.1 0.0 77.1 151.3 304.5 60.7 145.3 4.8 85.8 20.1 55.0 43.1 75.7 12.8 145.0 207.7 23.5 55.5 129.0 79.4 59.9 53.6 254.3 353.1 0.0 9.1 116.8 162.8 286.1 133.9 13.7 4.7 187.6 87.2 5.6 167.9 49.8 189.5 1.0 1.0 167.4 250.6 12.8 121.0 47.9 247.5 440.3 74.1 1.3 32.9 7.2 37.3 3.6 7.7 116.6 90.1 48.6 198.5 17.7 123.6 133.8 AC007906.2 ENSG00000277639 "Novel protein" 16 53035690-53052873 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "choroid plexus: 86.7;fallopian tube: 77.8" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 224.8;Respiratory ciliated cells: 209.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 31.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 8.3;ASC TERT1: 7.0;BEWO: 11.6;HSkMC: 7.1;RPTEC TERT1: 7.5" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.97e-2)" "unprognostic (8.34e-3)" "unprognostic (1.63e-1)" "unprognostic (5.38e-3)" "unprognostic (1.70e-1)" "unprognostic (5.75e-2)" "unprognostic (2.54e-1)" "unprognostic (1.06e-1)" "unprognostic (3.34e-1)" "unprognostic (2.25e-2)" "unprognostic (1.54e-2)" "unprognostic (5.02e-2)" "unprognostic (6.07e-2)" "unprognostic (5.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-2)" "unprognostic (4.46e-3)" 1.0 0.3 1.6 0.4 1.1 0.0 6.0 1.0 0.4 11.2 86.7 4.5 0.6 2.8 1.4 9.0 77.8 10.5 1.4 2.9 2.0 16.5 1.3 9.5 0.1 6.5 10.4 0.3 11.6 0.3 0.3 1.5 3.9 9.4 5.1 0.0 3.5 2.7 1.0 4.7 0.4 0.8 3.4 0.0 0.9 0.2 2.5 0.8 0.3 1.0 1.2 6.8 2.6 1.6 0.1 2.5 4.1 2.1 8.3 7.0 11.6 1.2 0.9 0.1 0.0 0.3 1.7 0.2 2.1 1.7 0.8 0.7 0.0 1.6 0.5 0.2 0.1 0.0 0.1 0.6 1.6 0.0 1.8 7.1 6.2 2.3 0.7 2.3 1.7 0.1 0.1 0.1 3.8 0.1 0.1 0.0 4.6 0.4 0.6 1.0 0.0 0.0 7.5 1.6 0.2 0.0 0.3 0.0 0.1 3.4 0.8 0.1 2.0 2.7 2.7 0.1 0.0 0.0 0.0 0.0 3.3 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.1 1.0 0.4 2.9 2.0 6.5 10.4 3.9 3.4 2.5 1.6 0.1 0.0 5.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.7 12.7 0.0 0.0 30.3 25.8 0.0 0.1 0.5 0.0 5.9 4.9 0.0 224.8 1.7 0.8 0.0 0.0 0.0 0.0 0.3 3.2 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.4 209.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 AC099489.1 ENSG00000188897 "Novel lipoprotein amino terminal region containing protein" 16 11359845-11527245 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 5.3;Glandular and luminal cells: 2.3;granulocytes: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 12 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.5" "Cell line enhanced" "Detected in some" "Daudi: 3.1;HDLM-2: 3.4;U-266/70: 1.7" "Not detected" "Not detected" HPA042154 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA042154: AB_2677877" "unprognostic (4.69e-2)" "unprognostic (3.80e-2)" "unprognostic (7.24e-2)" "unprognostic (5.91e-2)" "unprognostic (1.21e-3)" "unprognostic (7.91e-2)" "unprognostic (9.18e-2)" "unprognostic (6.08e-2)" "unprognostic (8.04e-2)" "unprognostic (5.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.04e-1)" "unprognostic (3.72e-6)" "unprognostic (3.18e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (4.33e-5)" 2.2 0.5 0.7 3.7 0.6 1.5 0.9 0.8 1.7 1.7 0.6 0.8 0.1 0.9 0.3 0.5 3.4 0.5 1.4 0.6 0.4 2.2 2.3 5.2 0.8 0.6 0.5 0.7 0.8 0.5 1.0 0.3 1.0 1.9 0.1 0.2 3.0 0.4 2.4 3.6 1.0 0.1 0.4 18.6 1.2 4.8 0.5 0.2 0.9 0.4 0.3 1.6 1.1 0.9 0.0 0.4 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 3.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.2 0.4 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.2 0.1 1.1 0.0 0.2 0.3 0.2 0.0 0.4 0.4 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.7 0.1 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 3.5 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.8 1.7 0.6 0.4 0.6 0.5 1.0 0.4 0.5 0.9 0.4 9.6 5.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 1.5 0.0 0.0 1.3 0.0 0.0 0.1 1.0 0.0 0.0 0.5 0.0 1.6 0.9 0.3 0.0 0.0 0.0 0.2 0.1 0.5 0.0 2.3 3.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 AC138647.1 ENSG00000226490 "Novel protein" 8 141514638-141518737 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 12 "brain: 4.0;testis: 9.9" "Group enriched" "Detected in some" 5 "Early spermatids: 226.6;Late spermatids: 66.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.2;hypothalamus: 4.0;medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.2 0.3 4.0 1.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 226.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 331.1;Hepatocytes: 810.5;Proximal tubular cells: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 126.3 74.2 56.9 44.4 64.9 32.5 79.1 63.7 63.9 24.9 68.4 168.7 170.0 29.0 29.8 30.3 24.4 46.9 223.7 53.2 59.8 378.2 1011.9 48.9 36.6 65.1 61.4 34.8 54.1 35.1 34.9 29.6 64.0 26.4 109.6 31.9 20.3 34.0 165.3 28.0 165.2 44.5 62.8 33.6 37.4 37.7 64.3 39.9 55.8 236.6 31.9 41.6 28.6 64.2 3.9 70.5 110.0 97.5 129.9 69.5 57.4 35.2 52.4 53.6 41.2 146.3 58.9 61.1 73.5 117.5 56.7 4.8 176.8 21.0 51.4 190.5 50.4 45.5 79.0 171.4 62.5 0.7 78.3 91.7 6.7 84.8 26.2 44.6 90.0 87.7 42.5 54.7 147.5 81.8 2.7 89.7 101.5 24.8 26.7 150.8 233.0 217.6 177.7 2.8 163.4 130.9 2.7 76.2 5.6 82.1 45.7 60.0 48.1 49.8 60.5 67.8 36.4 112.3 139.7 157.3 35.0 85.7 47.1 53.0 87.4 96.1 99.2 106.5 123.0 43.2 58.3 88.7 103.2 36.3 50.2 73.2 8.3 120.0 108.1 50.1 76.4 112.7 56.9 64.9 63.7 63.9 53.2 59.8 65.1 61.4 64.0 62.8 64.3 64.2 28.4 38.5 47.3 11.8 31.4 3.6 14.2 15.5 11.4 6.7 25.0 25.5 189.9 234.4 23.7 55.2 4.2 36.5 48.2 331.1 295.4 148.5 71.2 7.9 33.9 30.0 40.1 53.6 1.7 45.7 56.0 47.3 23.9 7.7 45.1 63.3 41.4 810.5 109.6 1.7 4.6 73.0 24.4 64.8 18.5 153.9 48.1 50.6 19.6 13.1 57.2 62.2 106.1 4.5 8.7 101.8 161.2 37.2 41.2 9.8 226.6 708.0 26.4 29.5 19.7 42.1 34.9 51.1 42.7 11.1 4.8 27.0 52.2 93.0 144.8 9.6 ACAD8 ENSG00000151498 "Acyl-CoA dehydrogenase family member 8" Q9UKU7 11 134253548-134265855 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism, Transcription, Transcription regulation" "Activator, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040689, HPA043903" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA040689: AB_2677080, HPA043903: AB_2678724" "unprognostic (5.00e-2)" "unprognostic (2.40e-2)" "prognostic favorable (7.62e-4)" "unprognostic (7.57e-3)" "unprognostic (9.83e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.53e-1)" "prognostic favorable (2.38e-4)" "unprognostic (4.10e-2)" "unprognostic (2.84e-1)" "unprognostic (7.81e-3)" "unprognostic (2.16e-1)" "prognostic favorable (6.42e-10)" "unprognostic (1.08e-1)" "unprognostic (1.17e-2)" "unprognostic (4.02e-2)" "unprognostic (1.03e-2)" 11.0 18.1 13.9 3.5 14.2 6.8 11.3 14.3 15.4 7.5 18.7 11.6 11.3 6.3 12.6 9.6 9.4 5.2 27.2 14.7 14.3 31.6 24.8 7.8 5.0 14.3 14.1 6.9 16.7 12.4 6.5 4.8 13.8 20.5 10.9 5.0 12.6 7.5 32.5 14.3 8.4 8.3 14.5 8.6 12.6 6.3 14.8 8.5 27.7 39.2 8.9 8.4 6.9 14.8 5.9 5.9 11.8 17.6 20.2 11.5 13.5 11.3 14.0 14.7 10.3 16.2 10.8 14.2 21.1 11.7 15.5 6.0 14.6 14.3 10.2 13.0 4.7 29.4 5.8 11.3 17.0 16.5 18.3 13.8 4.4 14.8 4.5 13.3 16.3 20.8 13.8 7.0 12.4 7.5 12.2 18.1 17.0 49.8 9.7 9.8 11.9 8.5 20.1 17.5 3.7 11.7 19.5 14.8 7.3 11.9 31.0 15.0 11.3 7.1 7.5 6.2 11.2 7.8 3.8 12.7 7.2 15.4 11.2 36.2 13.4 23.1 11.8 13.5 11.5 11.6 11.1 11.7 12.7 9.2 13.0 11.7 12.1 31.5 12.9 10.8 15.1 12.3 13.9 14.2 14.3 15.4 14.7 14.3 14.3 14.1 13.8 14.5 14.8 14.8 11.7 3.2 12.2 15.3 8.8 6.0 4.7 23.5 7.4 11.2 17.5 11.9 24.6 4.3 19.7 18.4 14.6 19.7 14.0 20.0 52.8 12.1 5.3 8.2 11.8 9.7 3.6 12.0 21.5 11.9 10.6 9.8 10.2 8.5 3.8 15.7 10.8 36.7 12.9 15.2 16.0 14.3 48.8 14.2 6.9 6.1 11.5 10.0 28.4 13.1 12.7 11.8 9.2 12.1 15.8 12.6 15.8 10.1 14.6 5.9 17.4 59.8 20.1 17.1 6.6 8.7 9.6 22.4 17.3 10.9 7.7 8.3 10.5 36.0 14.9 5.3 ACAD9 "MGC14452, NPD002" ENSG00000177646 "Acyl-CoA dehydrogenase family member 9" Q9H845 3 128879596-128924003 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037716, HPA046720" Supported Enhanced Mitochondria No No "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA037716: AB_10673638, HPA046720: AB_2679773" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.61e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.67e-6)" "unprognostic (1.30e-1)" "unprognostic (3.74e-1)" "unprognostic (3.25e-2)" "unprognostic (1.37e-1)" "unprognostic (6.96e-3)" "prognostic favorable (4.32e-8)" "unprognostic (1.52e-1)" "unprognostic (2.64e-2)" "unprognostic (6.56e-2)" "unprognostic (9.96e-2)" 16.7 20.5 9.0 6.1 8.5 4.7 14.5 9.6 10.2 14.4 9.1 13.6 9.0 14.6 7.7 23.2 12.9 7.3 21.9 8.3 8.7 15.6 20.6 11.0 6.6 8.2 8.7 12.9 14.4 27.7 14.6 8.4 8.4 12.1 9.4 4.1 14.2 12.0 30.4 48.0 11.2 11.1 7.4 12.2 15.9 12.5 8.7 12.1 13.6 28.7 11.2 12.9 14.5 9.0 46.2 22.6 18.0 12.6 28.7 20.7 17.5 22.4 26.2 43.6 36.8 33.3 27.1 33.3 21.1 29.5 29.0 35.5 33.8 45.9 32.8 21.2 23.1 29.3 46.8 24.4 21.6 23.9 10.6 22.5 16.8 23.6 26.7 25.1 35.8 25.2 14.4 11.4 29.5 46.5 36.7 19.0 9.9 49.3 33.8 25.5 17.4 35.1 30.9 25.1 19.0 11.6 37.0 32.9 23.2 17.4 44.5 54.8 18.2 13.2 13.4 14.2 20.3 14.5 5.8 28.3 28.3 21.4 22.7 2.4 15.1 4.9 8.3 18.3 7.8 8.1 7.6 7.3 17.5 5.4 6.2 8.0 0.7 6.8 25.2 9.9 8.3 12.1 9.0 8.5 9.6 10.2 8.3 8.7 8.2 8.7 8.4 7.4 8.7 9.0 10.4 16.0 21.7 13.1 9.3 6.2 11.4 16.7 8.6 14.1 11.9 9.5 30.5 15.7 14.8 14.7 10.4 26.2 10.5 11.7 21.5 20.6 20.2 10.4 11.5 11.2 5.4 14.3 14.3 17.8 18.8 12.9 16.8 12.9 16.5 12.0 15.7 26.7 31.5 10.1 17.7 7.4 16.2 9.5 4.0 17.3 10.2 10.8 16.0 7.5 13.4 15.0 12.3 6.0 12.2 14.1 8.7 14.7 9.5 8.1 9.4 26.3 12.0 11.9 13.1 12.7 14.9 22.6 9.6 13.5 14.2 30.6 8.2 18.1 14.3 8.4 ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.3;skeletal muscle: 380.0;tongue: 475.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 373.1;Distal tubular cells: 344.4;Hepatocytes: 261.2;Proximal tubular cells: 564.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 289.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Enhanced Mitochondria NA NA 930000 "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA006198: AB_1078087, HPA026542: AB_1844469" "unprognostic (9.04e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.30e-4)" "unprognostic (5.09e-3)" "unprognostic (1.61e-3)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (4.95e-2)" "unprognostic (9.40e-3)" "unprognostic (3.35e-1)" "prognostic favorable (3.83e-8)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-1)" 81.9 82.2 25.2 24.3 25.0 17.3 69.9 26.6 42.2 29.3 30.4 46.8 103.9 20.0 25.3 51.3 30.6 27.8 217.8 24.3 25.9 295.9 367.3 22.6 42.6 26.9 26.8 35.7 35.9 66.3 19.2 16.9 25.8 26.8 49.5 21.2 31.4 26.2 380.0 14.4 75.6 25.5 26.2 27.4 52.8 35.7 25.8 29.7 38.4 475.9 44.3 32.7 21.3 25.2 25.8 20.5 61.0 26.8 53.1 42.1 17.5 48.1 40.4 46.1 38.5 38.3 39.5 289.1 40.7 34.4 39.0 22.8 54.9 41.8 57.8 113.0 25.5 94.4 58.5 58.3 36.4 80.0 23.9 50.7 23.5 39.8 22.8 35.0 36.2 56.6 102.3 60.4 50.5 9.6 96.3 40.6 50.2 80.4 49.5 118.8 83.8 30.6 77.9 70.7 33.8 43.0 38.0 111.6 102.0 43.1 32.7 107.6 20.2 29.9 29.6 26.6 78.1 38.6 62.0 128.1 25.8 67.0 35.3 15.3 14.2 19.3 17.1 20.9 27.3 40.7 17.8 21.5 21.4 24.6 20.3 23.6 0.5 25.0 20.4 23.2 19.5 19.5 25.2 25.0 26.6 42.2 24.3 25.9 26.9 26.8 25.8 26.2 25.8 25.2 42.9 57.7 58.3 29.7 56.5 27.3 41.8 69.0 44.3 39.0 49.0 40.9 373.1 52.9 63.0 58.8 25.0 35.8 39.4 42.6 344.4 37.9 55.4 27.1 32.2 36.2 40.7 67.6 51.6 26.5 19.5 47.6 26.0 25.4 44.9 61.5 43.9 261.2 75.7 30.3 46.7 38.7 63.1 45.6 22.2 24.4 46.9 38.2 51.6 19.7 32.8 53.7 29.9 36.2 36.0 21.2 49.7 45.5 74.9 24.2 88.0 564.8 106.7 30.0 0.0 38.6 43.7 76.3 86.1 46.6 27.0 15.3 39.4 72.5 46.7 35.9 ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 3430.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.3;HDLM-2: 31.0;JURKAT: 42.4;Karpas-707: 29.4;NB-4: 37.9;U-937: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Approved "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" 5.6 1.1 0.4 18.9 0.5 41.0 2.1 0.5 0.8 2.3 0.5 7.4 4.1 1.5 0.3 4.2 4.0 3.6 2.1 0.3 0.4 4.6 5.2 16.1 39.5 0.6 0.5 0.9 1.2 0.1 1.3 0.5 0.6 3.8 2.1 0.2 3.6 0.4 0.9 2.5 43.3 0.9 0.5 96.0 5.0 0.8 0.8 25.8 5.2 0.8 22.6 4.3 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.0 23.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 8.8 0.1 0.0 0.1 11.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 42.4 0.0 29.4 0.0 0.0 14.5 37.9 0.4 0.0 0.0 15.1 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.0 0.1 0.0 0.0 9.1 8.2 10.9 0.1 24.9 0.0 28.8 7.9 30.8 29.6 2.4 33.3 20.2 31.5 32.1 13.7 21.3 26.7 27.5 22.6 32.5 0.4 17.3 39.0 22.3 0.4 0.5 0.5 0.8 0.3 0.4 0.6 0.5 0.6 0.5 0.8 0.6 3.8 9.6 5.5 1.6 150.9 8.3 7.6 25.1 2.8 15.8 7.0 8.1 32.9 7.2 12.3 5.5 18.8 3.9 160.7 2.0 7.9 3.9 498.1 8.3 5.4 5.0 3.6 22.9 0.3 3.7 3.2 8.0 5.6 3.4 40.5 1.8 7.1 5.3 7.5 0.0 1.9 2.7 8.2 26.2 39.5 3430.7 20.2 27.9 24.9 2.8 38.3 11.7 332.7 0.5 1.0 5.5 0.0 15.4 68.0 4.6 1.3 3.8 44.6 20.4 19.7 7.5 8.1 15.6 10.5 1.5 7.4 4.4 268.3 0.9 1.6 3.5 ACAT2 ENSG00000120437 "Acetyl-CoA acetyltransferase 2" Q9BWD1 6 159762045-159779112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 231.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 262.1;Early spermatids: 187.0;Exocrine glandular cells: 176.6;Hepatocytes: 214.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021106, HPA025736, HPA025765, HPA025811" Enhanced Approved Nucleoplasm,Cytosol NA NA 14000000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoplasm "CAB021106: AB_10058215, HPA025736: AB_1844487, HPA025765: AB_1844485, HPA025811: AB_1844488" "unprognostic (3.31e-1)" "unprognostic (2.44e-2)" "prognostic favorable (1.12e-4)" "prognostic unfavorable (7.25e-4)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (9.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.39e-1)" "unprognostic (1.50e-2)" "unprognostic (8.56e-2)" "unprognostic (2.54e-2)" 10.9 21.6 22.2 18.5 24.4 22.4 23.6 30.2 30.0 12.8 20.1 38.5 31.2 10.9 40.0 32.6 11.4 10.6 9.4 22.7 27.6 27.0 231.3 20.2 25.0 39.4 26.3 17.3 9.4 12.5 3.2 11.8 39.1 35.6 33.8 19.5 15.5 9.3 4.9 18.1 17.9 15.8 24.8 9.7 19.5 28.6 24.4 39.4 9.0 7.1 36.7 13.7 9.1 28.1 70.1 58.8 451.9 160.8 57.2 111.6 14.4 57.4 70.5 141.8 244.5 234.0 87.1 55.9 29.0 48.7 458.2 64.5 174.8 465.8 166.7 35.2 174.4 127.4 97.2 418.8 62.0 81.4 35.8 62.2 40.1 231.1 92.9 21.4 68.8 160.1 139.9 104.3 85.5 113.0 137.0 154.0 142.8 65.5 41.7 83.9 94.4 173.1 377.2 93.7 107.8 63.2 67.5 43.3 26.2 18.5 83.4 157.3 39.2 50.3 45.7 72.1 154.0 47.7 89.0 142.0 15.7 151.2 77.1 30.1 24.9 46.7 47.9 33.9 47.3 46.6 54.1 47.8 34.7 51.4 53.3 43.2 11.0 41.3 23.6 30.4 79.0 46.2 22.2 24.4 30.2 30.0 22.7 27.6 39.4 26.3 39.1 24.8 24.4 28.1 11.8 12.8 45.4 15.3 25.8 26.1 32.4 262.1 22.2 19.4 33.4 24.5 1.2 42.9 115.5 20.2 2.1 53.7 28.6 34.7 70.5 78.8 187.0 14.3 9.9 18.8 17.2 38.5 14.3 176.6 97.0 21.6 9.7 25.9 13.3 47.7 16.1 214.8 58.1 13.5 14.7 23.6 83.4 14.8 29.8 128.8 13.7 25.7 30.2 1.0 58.9 22.5 30.9 13.0 17.5 65.6 28.8 19.2 25.5 38.7 15.4 50.0 30.1 24.7 0.0 25.1 44.9 28.5 45.6 43.0 21.0 35.2 31.0 102.5 33.0 38.9 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACER1 ASAH3 ENSG00000167769 "Alkaline ceramidase 1" Q8TDN7 19 6306142-6333612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 88.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.7;Inhibitory neurons: 2.1;Melanocytes: 1.8;Spermatocytes: 1.7;Suprabasal keratinocytes: 5.8" "Group enriched" "Detected in some" 7 "head and neck cancer: 1.0;melanoma: 2.2;prostate cancer: 0.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Cell line enhanced" "Detected in single" "T-47d: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (1.13e-2)" "unprognostic (2.87e-4)" "unprognostic (5.04e-2)" "unprognostic (6.18e-2)" "unprognostic (8.16e-4)" "unprognostic (7.27e-4)" "unprognostic (2.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.99e-1)" "unprognostic (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.30e-5)" "unprognostic (2.11e-1)" "unprognostic (4.44e-2)" "unprognostic (4.22e-1)" "unprognostic (2.24e-1)" 0.1 0.1 0.1 0.1 0.1 0.1 3.3 0.4 0.2 3.4 0.3 0.0 0.0 0.2 0.2 12.2 0.2 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.5 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.2 1.7 0.0 0.0 3.2 0.1 0.5 88.1 0.2 0.1 0.0 0.3 0.0 1.1 0.2 1.3 0.0 0.0 0.7 0.0 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.2 0.5 0.0 0.1 0.7 0.7 0.1 0.3 0.0 0.1 0.8 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.1 0.9 1.0 1.8 0.0 0.0 0.0 0.0 1.0 0.5 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.7 1.0 0.0 5.8 0.0 0.4 0.0 0.0 0.1 ACO1 "IREB1, IREBP, IRP1" ENSG00000122729 "Aconitase 1" P21399 9 32384603-32454769 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Lyase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 134.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 194.4;Proximal tubular cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 194.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019371, HPA024157" Enhanced Supported Mitochondria,Cytosol NA NA 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA019371: AB_1844519, HPA024157: AB_1844520" "unprognostic (2.11e-1)" "unprognostic (5.61e-2)" "unprognostic (8.38e-2)" "unprognostic (9.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.12e-2)" "unprognostic (4.25e-3)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-1)" "unprognostic (2.55e-1)" "unprognostic (3.08e-1)" "prognostic favorable (5.73e-5)" "unprognostic (2.54e-1)" "unprognostic (6.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.23e-2)" 96.6 50.5 15.2 16.1 15.4 3.5 50.1 14.6 15.3 19.8 19.1 23.7 48.6 19.2 30.2 15.4 14.6 15.6 36.3 14.0 16.2 89.2 134.5 20.3 8.8 15.8 15.8 17.4 37.6 22.8 13.1 16.1 14.9 21.9 20.6 12.9 16.6 19.1 25.1 12.0 35.8 22.9 15.3 9.3 28.7 17.6 16.9 13.6 34.5 37.8 7.1 24.4 13.7 14.1 37.5 33.7 25.7 40.7 194.5 104.8 11.6 69.3 169.1 31.2 24.5 36.0 11.4 7.4 21.6 73.1 84.9 5.1 51.3 66.3 62.3 23.8 13.8 54.7 33.4 39.3 97.4 5.1 21.2 91.7 20.1 80.4 56.1 95.6 81.7 28.4 20.0 15.7 89.9 9.9 29.5 26.4 26.9 23.3 35.5 22.8 38.0 7.8 118.9 34.1 3.3 10.5 71.9 2.8 7.6 27.1 16.7 13.5 89.2 112.5 38.2 38.2 18.2 7.8 15.5 14.7 78.7 18.2 10.2 33.2 11.3 3.3 9.2 11.3 8.0 5.6 6.2 6.9 9.3 5.0 8.1 8.2 1.2 6.7 10.0 4.3 3.9 8.4 15.2 15.4 14.6 15.3 14.0 16.2 15.8 15.8 14.9 15.3 16.9 14.1 16.3 3.2 25.7 43.8 6.7 4.5 7.9 11.9 9.1 21.4 17.8 7.4 45.5 38.6 11.7 23.9 22.9 50.8 6.2 26.4 19.6 19.0 8.7 10.0 30.7 18.7 4.9 11.6 24.6 41.0 22.1 29.7 39.3 13.9 2.5 17.1 15.7 194.4 15.1 33.7 46.5 27.7 10.2 14.8 6.7 6.9 23.6 15.6 7.2 20.6 8.6 25.7 8.2 22.1 24.1 19.4 23.7 23.3 7.2 10.1 56.1 183.4 10.7 14.3 19.7 30.5 22.2 9.8 19.4 10.3 5.4 53.5 7.5 22.2 34.6 8.7 ACOT1 "ACH2, CTE-1, LACH2" ENSG00000184227 "Acyl-CoA thioesterase 1" Q86TX2 14 73537143-73543796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 10.7;Cardiomyocytes: 51.5;Excitatory neurons: 13.8;Inhibitory neurons: 12.0;Oligodendrocyte precursor cells: 8.5;Oligodendrocytes: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 30.5;T-47d: 49.8" HPA043705 Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043705: AB_2678626" "unprognostic (4.74e-3)" "unprognostic (3.81e-3)" "unprognostic (7.65e-2)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (1.29e-1)" "unprognostic (4.54e-2)" "unprognostic (1.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "prognostic favorable (5.09e-8)" "unprognostic (1.35e-3)" "unprognostic (4.60e-2)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" 15.1 12.9 10.4 3.6 10.2 2.4 13.0 9.3 11.3 5.7 8.4 12.9 10.8 13.2 11.6 3.4 7.3 3.5 18.6 10.1 9.7 25.9 44.4 7.3 2.3 9.2 10.1 3.5 3.0 2.2 2.0 2.9 9.6 5.6 5.4 2.9 5.1 9.3 19.6 8.9 11.8 20.9 9.5 2.6 6.4 4.2 11.1 2.5 3.6 29.3 2.1 9.5 4.0 9.6 10.7 9.0 3.3 0.7 15.2 9.1 0.1 2.9 8.5 7.0 12.6 3.9 6.9 0.0 0.4 5.8 0.9 6.0 0.0 1.4 3.4 4.5 2.8 4.6 2.8 30.5 14.4 0.1 5.1 12.0 0.6 5.6 0.0 0.7 3.2 0.0 0.0 0.0 5.5 4.7 0.6 1.0 3.4 1.4 4.9 9.5 6.8 0.2 6.9 8.7 4.9 6.4 9.0 20.2 12.2 0.9 49.8 9.9 4.2 5.2 7.5 4.2 0.7 0.1 0.0 2.6 6.2 0.0 6.8 0.7 0.9 0.7 4.1 1.1 3.5 2.6 3.9 3.4 3.8 1.9 3.5 3.9 0.1 3.5 1.1 2.2 5.1 2.6 10.4 10.2 9.3 11.3 10.1 9.7 9.2 10.1 9.6 9.5 11.1 9.6 0.2 0.0 3.2 10.7 0.0 0.0 0.1 0.6 1.8 0.0 0.4 0.4 51.5 0.0 0.4 0.0 0.0 0.7 1.3 0.2 0.0 0.4 0.6 0.3 0.3 0.7 0.0 2.7 13.8 8.0 0.3 2.6 0.0 0.3 0.0 0.1 0.0 1.1 0.9 0.0 12.0 0.0 2.0 0.3 0.0 0.0 0.0 0.5 1.8 3.7 0.0 0.0 0.0 8.5 15.1 2.6 0.0 0.4 0.3 0.0 0.0 3.7 0.3 0.0 0.0 0.0 3.6 0.1 0.2 0.6 0.0 0.8 0.2 0.0 0.2 0.0 ACOT2 "Mte1, ZAP128" ENSG00000119673 "Acyl-CoA thioesterase 2" P49753 14 73567620-73575658 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 118.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.0;Exocrine glandular cells: 33.2;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.4" "HPA043705, HPA060170" Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA043705: AB_2678626, HPA060170: AB_2732642" "unprognostic (4.44e-3)" "unprognostic (1.68e-2)" "unprognostic (3.17e-1)" "unprognostic (8.66e-2)" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (2.78e-2)" "unprognostic (6.61e-2)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (1.64e-1)" "prognostic favorable (2.28e-6)" "unprognostic (1.66e-3)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (4.35e-1)" 92.3 47.7 10.0 7.0 10.3 5.6 48.9 9.2 12.4 17.1 12.2 42.2 24.7 42.9 10.7 10.9 24.1 6.1 94.5 10.1 9.5 49.4 118.9 17.3 4.7 8.8 9.4 11.7 12.8 22.4 8.3 4.4 8.2 17.8 11.1 4.1 17.8 11.1 114.0 13.1 24.5 22.8 9.2 11.4 22.5 12.0 13.0 3.7 14.5 50.0 3.3 31.2 13.3 9.0 22.8 25.0 4.9 22.1 21.3 7.9 1.0 13.7 31.5 21.9 28.6 18.1 12.6 0.1 9.7 7.0 10.3 12.7 0.0 1.2 11.4 33.1 31.6 16.0 7.6 62.4 14.5 0.1 43.3 19.5 0.0 7.6 0.1 21.0 9.5 0.0 0.0 0.1 18.7 7.4 2.5 18.2 7.5 2.3 37.8 37.2 21.9 0.3 8.0 9.5 21.6 27.3 33.1 24.3 29.6 2.1 51.1 12.7 17.0 17.9 47.2 11.8 13.0 0.0 0.1 9.5 15.8 0.1 18.2 3.5 5.9 3.1 22.1 7.0 15.8 15.0 20.2 16.6 21.9 12.4 17.8 19.9 0.2 15.3 6.5 13.6 31.3 13.6 10.0 10.3 9.2 12.4 10.1 9.5 8.8 9.4 8.2 9.2 13.0 9.0 4.3 0.0 6.4 3.3 6.6 1.7 1.0 5.9 16.5 1.1 5.2 4.2 50.0 7.2 3.0 7.3 10.4 6.1 3.0 20.1 13.7 20.9 1.5 1.4 1.9 4.0 15.7 8.4 2.9 33.2 3.2 7.0 11.7 2.1 13.4 1.9 4.2 27.7 14.9 1.7 3.1 15.5 10.2 3.8 1.6 1.1 5.9 5.6 5.4 1.0 18.5 5.5 7.2 3.0 1.7 21.8 8.6 8.2 7.9 0.4 27.5 36.5 3.3 4.9 6.6 1.4 9.8 0.3 4.8 8.5 0.4 8.2 5.8 1.7 18.8 0.4 ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.0;liver: 16.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 26.4;Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.6;MCF7: 14.1;SK-BR-3: 27.9;T-47d: 69.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" 4.9 1.4 3.7 1.1 3.7 0.6 4.6 4.2 4.3 3.9 2.4 3.0 4.3 0.8 2.6 1.5 0.9 0.9 0.9 3.6 2.9 15.0 16.8 3.6 1.3 3.1 2.7 0.9 1.5 1.0 0.4 1.8 3.3 1.4 3.4 0.8 1.7 1.8 0.6 0.6 3.3 1.5 2.5 1.5 2.0 2.2 2.9 1.0 1.3 0.6 1.3 1.2 0.9 3.2 10.7 2.9 0.3 0.1 1.3 0.6 0.0 0.6 0.0 0.7 1.2 0.3 17.6 0.0 0.6 1.0 0.0 1.1 0.0 0.1 0.1 5.8 0.1 0.0 3.5 0.0 2.0 0.0 9.5 0.8 1.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.6 14.1 0.3 1.9 0.9 3.7 2.8 0.0 0.0 0.0 0.4 5.2 1.5 0.3 6.9 27.9 2.1 0.1 69.7 10.5 0.2 0.0 6.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 11.5 0.0 1.4 14.7 0.6 7.3 2.1 6.9 8.4 0.4 3.3 4.0 8.5 0.0 7.2 0.2 0.9 7.2 5.3 3.7 3.7 4.2 4.3 3.6 2.9 3.1 2.7 3.3 2.5 2.9 3.2 0.4 0.0 2.7 1.0 1.0 0.3 1.1 3.8 1.2 0.2 5.5 4.2 1.7 7.2 2.8 11.0 0.0 15.9 3.6 8.3 15.6 4.2 1.8 4.1 1.1 0.5 0.0 0.0 1.4 9.2 13.8 1.5 3.1 5.6 5.7 4.1 0.0 26.4 11.2 1.7 0.8 3.2 8.2 3.0 0.3 5.3 0.3 2.1 0.0 1.9 1.0 0.7 11.3 0.5 0.3 6.2 2.6 0.4 1.5 1.1 15.7 59.8 2.9 0.5 0.0 1.5 1.1 3.2 15.8 2.6 0.3 4.5 5.1 0.4 2.6 1.3 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 104.2;Late spermatids: 90.3;Proximal enterocytes: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 8.3 31.7 27.8 8.6 29.8 18.1 7.6 28.2 35.2 9.3 24.3 18.5 21.1 8.5 11.0 17.5 10.7 9.2 28.1 29.8 28.6 21.3 26.0 11.0 12.6 27.0 28.5 8.0 15.6 15.1 15.4 7.1 28.7 12.7 12.8 9.2 12.8 5.9 28.7 17.0 20.5 6.4 26.0 12.3 21.3 20.2 28.7 13.1 11.4 17.8 9.7 11.0 10.4 28.1 16.8 20.2 6.8 13.4 18.3 11.0 11.7 11.1 9.5 15.1 13.7 29.2 22.7 20.8 48.2 16.3 35.4 32.3 13.0 27.8 6.6 15.5 22.3 21.2 25.1 28.5 16.9 19.9 19.3 12.9 21.3 15.1 10.9 22.6 9.4 23.6 18.8 24.2 11.0 47.4 28.7 27.0 11.8 32.4 52.2 14.0 12.2 37.6 16.5 19.1 23.1 10.8 24.9 61.7 39.5 10.6 34.4 48.8 11.6 37.9 8.5 19.5 18.9 20.7 33.8 14.0 46.3 21.2 20.8 34.3 34.3 43.6 24.8 34.6 21.8 27.5 23.2 21.9 36.7 27.9 20.0 21.6 25.0 16.3 34.2 23.3 31.9 26.7 27.8 29.8 28.2 35.2 29.8 28.6 27.0 28.5 28.7 26.0 28.7 28.1 8.2 35.3 14.1 5.9 17.9 6.1 12.3 21.9 8.6 19.2 9.8 10.9 9.3 11.5 17.7 12.9 16.7 34.2 11.8 104.2 64.6 21.6 38.5 14.2 10.4 10.9 19.2 17.0 12.3 21.0 20.9 11.4 19.9 14.0 14.0 27.6 11.4 25.5 27.8 8.4 12.0 37.3 10.2 18.6 7.1 90.3 9.9 17.5 10.6 3.7 27.5 17.8 34.0 5.0 9.6 21.6 68.4 8.6 21.3 11.3 105.4 81.5 27.1 22.8 13.1 5.8 12.8 27.0 10.2 16.1 8.0 19.4 13.9 37.6 30.3 16.0 ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.0;Proximal enterocytes: 27.9;Proximal tubular cells: 51.0" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.4;ASC TERT1: 25.9;fHDF/TERT166: 9.2;Hep G2: 10.8;HSkMC: 17.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" 8.8 8.3 4.1 2.1 4.6 0.1 5.8 4.4 4.5 9.3 16.8 12.9 25.4 9.4 5.8 6.3 10.8 8.2 16.7 4.3 4.5 42.1 177.3 6.2 1.7 5.3 4.8 11.2 4.6 9.6 4.6 3.4 4.4 10.8 8.3 1.8 7.2 9.8 8.2 2.9 21.6 11.2 4.5 1.4 4.0 4.9 4.9 4.0 16.1 17.0 1.2 8.7 6.0 4.1 0.0 0.0 0.2 0.0 16.4 25.9 4.7 3.1 0.2 0.0 0.4 0.8 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.6 4.4 4.5 4.3 4.5 5.3 4.8 4.4 4.5 4.9 4.1 1.9 3.2 5.8 11.1 0.6 0.6 7.6 0.5 5.7 0.3 1.3 3.8 14.3 4.3 0.9 3.7 0.0 0.7 0.0 4.2 15.6 0.3 0.1 0.4 1.3 1.6 3.0 2.7 0.6 1.9 0.4 8.6 2.0 0.2 1.3 8.6 6.1 89.0 5.2 1.7 0.6 5.1 0.0 1.9 0.4 1.8 10.8 1.7 0.0 1.0 0.5 10.8 0.0 0.5 0.0 0.4 0.8 8.6 0.1 0.6 27.9 51.0 0.0 0.8 6.6 7.0 5.2 0.4 0.4 3.0 0.3 0.8 0.3 9.6 4.6 3.8 ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 6.6;lymphoid tissue: 2.6;skin 1: 6.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 0.8;head and neck cancer: 2.6;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 33.3;U-87 MG: 45.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "HPA042613: AB_10963214" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-3)" "unprognostic (1.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (4.94e-3)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" "unprognostic (1.51e-5)" "unprognostic (4.36e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-2)" "unprognostic (2.42e-1)" 0.0 0.0 1.7 0.0 3.3 0.0 0.2 6.6 2.7 0.7 0.8 0.0 0.0 0.0 0.4 0.7 0.0 0.2 0.0 2.0 2.2 0.0 0.0 0.0 0.0 3.9 3.7 0.0 0.0 0.3 0.0 0.0 3.8 0.3 0.0 0.0 0.5 0.0 0.0 6.0 0.0 0.0 2.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 2.6 0.1 0.6 4.1 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.6 0.8 0.4 5.2 0.0 0.0 0.0 33.3 0.3 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.5 0.3 0.0 0.1 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.1 1.1 0.0 0.0 0.0 0.0 0.0 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.3 6.6 2.7 2.0 2.2 3.9 3.7 3.8 2.0 3.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 ACSBG1 "BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352" ENSG00000103740 "Acyl-CoA synthetase bubblegum family member 1" Q96GR2 15 78167468-78245688 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 56.6;skin 1: 14.3" "Cell type enriched" "Detected in some" 5 "Astrocytes: 158.0" "Cancer enriched" "Detected in some" 4 "glioma: 3.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 3.1;SK-MEL-30: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041642, CAB045955, HPA058869" Approved Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB045955: AB_11124196, HPA041642: AB_2677593, HPA058869: AB_2683840" "unprognostic (1.28e-1)" "unprognostic (1.63e-2)" "unprognostic (1.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.29e-2)" "unprognostic (4.18e-2)" "unprognostic (1.32e-2)" "unprognostic (1.58e-2)" "unprognostic (1.86e-1)" "unprognostic (5.64e-2)" "unprognostic (2.02e-1)" "unprognostic (4.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (4.19e-2)" "unprognostic (1.42e-2)" 0.1 5.5 23.0 0.4 42.6 2.4 1.6 30.5 24.0 0.5 0.0 1.1 0.4 0.2 0.7 0.3 2.8 0.2 0.8 19.6 35.9 0.5 0.4 0.5 0.4 46.0 39.9 0.3 0.2 0.0 0.5 0.1 47.7 0.8 0.1 0.6 0.3 0.2 0.2 14.3 0.5 0.2 45.8 0.3 0.3 3.7 36.6 3.4 0.2 0.0 0.1 0.3 0.5 56.6 0.3 0.0 0.6 0.9 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.3 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.5 0.3 0.6 0.3 0.0 0.2 0.6 0.2 0.0 0.1 0.1 0.2 0.0 0.4 0.2 0.4 0.0 0.1 0.2 0.5 3.1 0.2 0.1 0.1 0.4 0.2 0.0 0.4 0.2 0.3 0.1 0.4 1.5 0.3 0.1 0.2 0.4 0.2 0.2 0.1 0.1 0.3 0.1 0.3 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 0.3 23.0 42.6 30.5 24.0 19.6 35.9 46.0 39.9 47.7 45.8 36.6 56.6 0.1 0.0 2.0 158.0 0.6 1.1 0.6 0.3 0.6 1.9 0.2 0.1 3.0 0.0 2.7 0.0 4.2 0.2 0.5 0.3 0.0 0.0 1.8 4.4 0.3 0.2 0.0 4.6 0.7 0.0 0.2 0.7 0.5 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 1.7 0.3 4.0 1.8 2.8 0.1 0.2 1.0 7.5 26.9 0.2 0.0 0.0 0.9 0.3 0.1 0.2 19.1 3.3 0.0 0.3 1.0 2.0 10.0 0.4 0.6 0.4 0.5 1.6 0.1 0.7 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 217.8;intestine: 418.0;liver: 165.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.9;Endometrial ciliated cells: 159.9;Glandular and luminal cells: 292.3;Proximal enterocytes: 462.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 138.8;RT4: 143.3;U-937: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" 23.8 4.2 13.1 29.0 12.6 16.2 21.3 13.0 15.5 51.4 10.4 111.7 358.9 30.3 217.8 7.9 45.0 21.5 9.4 12.1 13.4 9.0 165.5 35.6 28.0 14.4 13.1 17.0 5.5 2.2 2.6 8.6 14.9 12.3 116.6 1.5 5.5 20.3 3.9 3.4 418.0 15.5 14.0 25.7 44.2 9.6 15.3 16.4 7.2 8.8 28.0 76.3 7.6 13.2 38.6 0.9 0.7 0.1 2.5 0.4 3.3 1.1 7.3 0.3 0.6 34.8 138.8 46.7 8.4 1.9 6.8 0.3 0.0 0.2 0.8 39.4 0.0 36.5 1.3 60.9 8.8 57.3 59.2 5.9 0.0 0.8 0.0 2.7 2.8 0.0 0.1 20.6 0.1 0.0 0.1 26.3 0.1 32.2 1.3 12.9 0.2 28.6 3.8 143.3 0.1 0.9 55.8 21.0 0.1 0.1 0.1 31.7 40.5 0.5 0.4 2.2 2.5 14.8 0.1 22.6 1.2 70.5 0.1 27.4 15.1 27.5 25.2 27.9 24.9 16.3 20.4 27.8 31.1 13.1 13.8 21.4 3.9 26.1 27.7 9.8 41.5 21.1 13.1 12.6 13.0 15.5 12.1 13.4 14.4 13.1 14.9 14.0 15.3 13.2 23.4 12.8 51.3 0.0 20.1 3.8 10.3 10.7 8.6 0.1 7.0 4.6 1.7 12.8 23.6 0.0 4.2 1.8 10.5 164.9 0.0 13.3 92.6 159.9 37.6 24.7 40.8 10.7 1.3 6.4 2.6 5.7 41.8 292.3 17.2 0.5 16.1 88.6 18.9 0.0 1.1 79.0 0.0 22.4 57.8 42.6 15.8 24.9 3.6 17.8 11.5 0.1 16.5 1.0 1.0 48.0 122.4 12.0 20.3 7.1 462.5 0.2 8.2 1.2 0.0 0.8 3.3 4.0 1.9 3.3 1.7 0.7 24.0 6.4 103.3 50.0 ACSM3 "SA, SAH" ENSG00000005187 "Acyl-CoA synthetase medium chain family member 3" Q53FZ2 16 20610243-20797581 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 85.1;liver: 178.5" "Cell type enhanced" "Detected in many" "Granulosa cells: 446.7;Hepatic stellate cells: 100.6;Proximal tubular cells: 136.0;Theca cells: 208.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 23.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 95.1;HMC-1: 381.7;K-562: 285.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041013 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA041013: AB_10671693" "unprognostic (1.62e-4)" "unprognostic (1.30e-2)" "unprognostic (2.12e-2)" "unprognostic (9.50e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.42e-2)" "unprognostic (2.20e-1)" "unprognostic (8.14e-3)" "prognostic favorable (1.97e-4)" "unprognostic (3.56e-2)" "unprognostic (1.95e-3)" "prognostic favorable (9.88e-6)" "unprognostic (1.27e-1)" "unprognostic (6.96e-2)" "unprognostic (1.06e-1)" "unprognostic (1.84e-2)" 4.5 3.2 1.7 2.4 1.6 15.3 60.2 2.1 3.1 10.3 1.9 26.4 7.7 19.9 5.7 3.2 26.8 10.4 8.6 1.7 0.8 85.1 178.5 8.1 3.1 3.1 2.7 74.8 30.4 15.2 0.9 2.5 2.5 22.0 25.6 1.0 4.8 6.9 0.8 4.3 8.2 5.1 1.0 1.9 28.1 5.9 2.2 2.8 2.8 1.0 2.9 4.9 5.2 5.3 1.0 12.4 2.3 0.7 3.9 2.3 1.5 0.2 1.3 0.3 1.0 1.0 18.2 1.6 20.1 0.4 0.7 1.6 0.2 2.1 1.6 4.5 6.6 95.1 0.2 7.7 1.3 10.9 381.7 3.7 2.2 0.5 1.4 1.9 0.2 0.7 285.1 15.3 0.1 1.5 0.7 3.5 0.7 14.5 3.8 3.1 0.1 20.3 18.3 1.1 0.8 0.7 0.4 5.4 0.3 0.8 6.1 0.9 1.3 1.2 1.2 0.9 0.7 21.9 18.6 1.2 1.2 7.5 0.5 2.6 2.0 23.5 3.6 1.2 4.2 1.6 4.5 3.3 0.2 2.8 6.9 8.2 0.5 2.3 4.0 2.3 5.6 2.9 1.7 1.6 2.1 3.1 1.7 0.8 3.1 2.7 2.5 1.0 2.2 5.3 0.3 3.2 31.3 1.0 16.5 2.8 34.6 1.5 8.0 0.0 6.3 6.1 3.2 20.0 1.7 12.9 0.0 19.1 1.5 7.0 84.1 84.8 25.0 14.0 4.3 3.4 2.4 25.4 0.3 12.5 2.1 23.7 8.6 32.8 0.0 446.7 100.6 38.2 3.2 0.0 0.3 11.8 0.0 5.4 1.7 12.3 27.7 3.4 0.0 0.0 3.1 0.0 4.1 0.0 0.1 8.9 20.3 12.8 1.0 14.5 4.7 136.0 1.5 0.0 0.0 0.4 52.7 6.9 2.2 3.8 1.8 19.2 4.3 208.3 23.0 11.3 ACSM6 "bA310E22.3, C10orf129" ENSG00000173124 "Acyl-CoA synthetase medium chain family member 6" Q6P461 10 95194200-95228928 "Enzymes, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 3.6;pancreas: 4.0;skin 1: 1.9;stomach 1: 1.9;urinary bladder: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.0;Cone photoreceptor cells: 2.1;Early spermatids: 2.4;Excitatory neurons: 3.8;Inhibitory neurons: 3.4;Oligodendrocytes: 2.1;Rod photoreceptor cells: 5.3" "Cancer enriched" "Detected in single" 7 "urothelial cancer: 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "RT4: 3.7" HPA044593 Uncertain NA NA "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA044593: AB_10960261" "unprognostic (2.91e-2)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (5.73e-2)" "unprognostic (2.48e-2)" "unprognostic (6.34e-2)" "unprognostic (1.41e-2)" "unprognostic (1.91e-1)" "unprognostic (3.75e-3)" "unprognostic (2.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favorable (7.71e-4)" 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.9 0.1 0.1 3.6 0.4 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 2.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.4 0.6 1.2 0.6 0.0 0.0 3.8 0.0 0.0 0.1 1.1 1.1 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 5.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 117.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 137.7;Hepatocytes: 138.9;Intestinal goblet cells: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.3" "Group enriched" "Detected in many" 5 "dendritic cells: 22.6;granulocytes: 34.3;monocytes: 21.8" "Cell line enhanced" "Detected in many" "HBEC3-KT: 132.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004141 Approved NA NA 16000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA004141: AB_1078094" "unprognostic (1.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (3.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.42e-2)" "prognostic favorable (2.04e-4)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-1)" "unprognostic (2.54e-1)" 69.3 23.7 4.0 10.7 9.3 7.5 27.2 6.8 7.8 15.1 6.0 54.6 64.2 13.7 34.3 18.6 22.1 10.7 49.8 3.3 6.4 22.0 46.9 23.2 4.0 12.1 5.9 13.0 14.8 19.6 3.8 17.2 12.7 12.2 32.9 5.3 38.1 16.2 117.3 17.1 46.8 11.3 5.1 8.1 37.7 10.6 7.2 4.0 9.6 99.2 7.0 9.3 11.9 16.3 32.8 11.6 17.1 10.7 69.5 59.1 25.5 14.5 32.4 13.9 21.7 27.3 40.6 0.1 18.6 24.1 50.2 26.0 20.1 132.4 9.5 0.1 7.1 37.2 6.6 18.5 46.2 6.6 28.1 50.3 34.2 24.8 34.5 27.8 27.7 4.2 22.0 7.1 15.8 13.3 2.4 18.8 3.3 27.6 44.1 15.9 20.3 83.4 62.5 9.0 2.9 14.5 24.7 49.1 32.1 21.2 19.6 24.4 23.5 12.3 7.8 12.4 7.9 24.0 19.7 9.1 32.3 9.3 9.1 34.3 21.8 6.6 1.2 13.3 1.2 0.7 3.0 1.3 22.6 1.1 5.3 2.9 12.2 0.7 6.4 4.2 2.0 9.2 4.0 9.3 6.8 7.8 3.3 6.4 12.1 5.9 12.7 5.1 7.2 16.3 8.8 12.8 41.1 17.6 4.2 7.8 9.4 13.5 10.2 6.4 27.6 10.9 82.2 20.0 16.6 11.0 6.2 15.5 3.7 137.7 11.7 20.8 9.0 8.0 8.2 13.5 7.8 29.0 18.5 33.7 11.2 11.4 58.1 13.0 9.5 35.3 13.6 138.9 16.4 8.4 18.2 100.6 18.3 17.9 13.9 7.2 11.5 15.6 14.2 17.8 19.4 9.1 1.0 5.5 86.5 23.4 66.4 4.5 14.6 11.2 70.4 60.5 7.6 4.1 13.1 7.2 9.8 32.1 20.3 12.3 10.9 20.9 5.1 7.8 75.1 13.0 ACTA1 "ACTA, NEM3" ENSG00000143632 "Actin alpha 1, skeletal muscle" P68133 1 229431245-229434098 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skeletal muscle: 133409.0" "Group enriched" "Detected in some" 36 "Cardiomyocytes: 1901.9;Skeletal myocytes: 1541.2" "Group enriched" "Detected in many" 18 "head and neck cancer: 133.1;prostate cancer: 34.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 22 "BEWO: 469.2" "Low region specificity" "Detected in all" "CAB000045, HPA041264, HPA041271" Enhanced NA NA 2800000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "CAB000045: AB_2242301, HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (5.59e-2)" "unprognostic (1.60e-2)" "unprognostic (1.77e-1)" "unprognostic (3.07e-4)" "unprognostic (5.75e-3)" "unprognostic (3.84e-3)" "unprognostic (1.86e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (2.64e-3)" "unprognostic (2.50e-1)" "unprognostic (1.56e-3)" "unprognostic (9.40e-4)" "unprognostic (2.61e-1)" "unprognostic (1.58e-2)" "unprognostic (1.01e-1)" 15.3 3.8 1.2 1.6 1.2 0.3 19.8 1.8 2.8 1.2 0.4 8.8 0.3 3.0 0.0 604.6 0.6 1.6 6656.6 1.2 3.5 2.6 7.3 7.6 2.2 0.9 1.1 4.6 7.3 0.0 4.7 1.2 0.8 164.8 0.0 0.1 591.0 0.7 133409.0 36.0 5.3 66.3 0.7 3.0 5.1 2.5 1.4 3.1 14.5 20867.7 0.9 3.0 5.4 1.0 0.2 0.2 0.1 0.4 0.0 0.1 469.2 0.0 0.0 0.3 0.1 0.5 0.1 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 1.4 0.2 0.5 21.5 0.0 0.5 0.7 20.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.2 0.5 0.2 0.0 0.2 0.3 0.3 0.2 0.0 0.3 0.2 0.5 0.2 4.3 0.1 0.0 0.3 0.4 0.6 0.3 0.2 0.5 0.5 0.6 1.0 0.3 0.3 0.6 0.3 18.3 16.5 34.2 11.5 25.4 8.4 6.7 9.4 11.2 23.6 6.4 7.2 11.5 18.8 8.2 24.1 7.5 15.7 45.4 1.2 1.2 1.8 2.8 1.2 3.5 0.9 1.1 0.8 0.7 1.4 1.0 0.2 0.0 0.0 0.3 0.1 0.5 0.4 0.8 0.0 0.8 0.3 2.2 1901.9 0.0 0.1 0.0 4.2 1.7 0.0 0.0 0.0 1.9 0.4 0.1 0.4 38.1 0.0 0.0 0.6 0.0 3.3 43.6 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 2.1 0.3 0.0 9.7 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.4 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1541.2 46.6 1.1 0.2 0.7 0.4 0.3 8.2 0.1 0.1 0.2 ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6678.8;seminal vesicle: 5920.3;smooth muscle: 8099.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1007.7;Peritubular cells: 5290.7;Sertoli cells: 3030.6;Smooth muscle cells: 2394.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 390.6;fHDF/TERT166: 641.1;HHSteC: 625.8;HSkMC: 345.1;hTERT-RPE1: 743.4;SuSa: 296.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 101.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" 1035.2 241.6 54.0 728.1 61.4 3.9 838.4 52.7 121.1 2000.3 61.4 2755.1 248.9 6678.8 1360.1 1509.9 3104.3 906.1 1069.2 53.4 54.6 312.2 161.8 732.8 173.7 59.0 55.9 798.0 91.4 80.6 60.8 771.3 55.3 2642.8 866.4 8.2 414.7 5920.3 202.1 355.7 701.6 8099.9 54.1 452.1 1427.1 263.9 56.1 56.5 312.0 214.0 48.4 3002.5 1367.0 52.9 3.9 19.0 49.3 102.7 198.1 390.6 9.5 109.8 136.8 11.9 45.4 0.0 8.8 7.2 11.5 641.1 8.6 1.4 1.8 25.4 11.3 60.6 11.3 0.4 5.6 119.3 625.8 0.8 3.2 345.1 44.9 73.9 28.5 743.4 11.3 3.0 0.0 7.1 128.8 10.8 1.0 28.3 2.5 0.2 1.2 1.4 0.2 4.6 27.1 5.0 0.7 7.6 10.2 7.9 1.0 296.8 32.4 1.0 27.9 24.0 4.0 30.2 9.3 21.1 1.6 0.6 29.6 10.2 26.1 28.1 12.3 17.5 17.6 8.7 13.8 6.0 14.1 19.8 10.8 1.8 1.5 10.7 11.1 4.0 14.2 0.4 58.7 10.7 54.0 61.4 52.7 121.1 53.4 54.6 59.0 55.9 55.3 54.1 56.1 52.9 65.4 9.6 6.1 5.5 4.4 43.2 23.4 16.5 22.8 1.1 22.7 1007.7 25.1 2.8 5.2 0.0 6.2 16.3 7.3 1.9 1.9 1.8 11.1 11.1 225.4 41.1 0.0 4.0 3.6 0.9 16.8 316.3 10.7 8.2 5.7 448.9 474.0 4.6 37.7 0.0 1.1 2.7 4.1 5.4 67.6 48.8 141.4 12.6 55.2 61.8 4.2 13.4 4.1 1.0 0.3 2.0 3.0 5290.7 3.7 17.5 3.4 9.5 10.9 1.4 3030.6 72.0 2394.6 4.0 13.8 11.1 40.5 23.7 16.5 36.0 5.7 10.4 ACTBL2 DKFZp686D0972 ENSG00000169067 "Actin beta like 2" Q562R1 5 57480018-57482811 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.1;Club cells: 1.0;Ductal cells: 1.7;Early spermatids: 2.4;Exocrine glandular cells: 1.1;Pancreatic endocrine cells: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 1.3;RPTEC TERT1: 1.6;SiHa: 2.9;U-2 OS: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041264, HPA041271" Uncertain NA NA 830000000 "Cluster 38: EFO-21 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.83e-2)" "unprognostic (1.70e-1)" "unprognostic (2.96e-1)" "unprognostic (8.66e-2)" "unprognostic (2.57e-2)" "unprognostic (2.39e-1)" "unprognostic (3.63e-2)" "unprognostic (1.22e-1)" "unprognostic (1.14e-3)" "unprognostic (3.20e-1)" "unprognostic (2.48e-3)" "unprognostic (1.60e-2)" "unprognostic (2.04e-2)" "unprognostic (1.92e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 1.1 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 ACTC1 "ACTC, CMD1R" ENSG00000159251 "Actin alpha cardiac muscle 1" P68032 15 34790230-34795549 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "heart muscle: 11410.0" "Cell type enriched" "Detected in some" 30 "Cardiomyocytes: 9746.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 1131.8;LHCN-M2: 4544.5;RH-30: 2053.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037330, HPA041264, HPA041271" Enhanced NA NA 2400000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB037330: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (8.18e-3)" "unprognostic (3.74e-2)" "unprognostic (4.82e-3)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.72e-5)" "unprognostic (3.26e-1)" "unprognostic (2.05e-3)" "unprognostic (2.26e-1)" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (2.10e-3)" "unprognostic (5.68e-4)" "unprognostic (8.79e-2)" "unprognostic (1.65e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (9.32e-4)" 51.1 1.8 1.9 24.7 1.7 0.0 11.9 2.1 2.6 8.6 1.3 4.0 0.8 6.9 1.1 22.8 1.6 11.8 11410.0 1.9 2.8 1.5 0.6 3.9 2.6 2.7 2.8 3.2 12.9 1.0 2.2 8.9 3.0 73.0 3.6 31.6 11.5 538.1 135.2 4.6 0.6 8.8 1.4 1.3 9.3 0.5 4.0 11.3 2.4 195.0 0.2 439.6 16.1 1.5 0.0 0.2 0.1 0.0 0.2 3.3 0.2 2.2 0.7 5.2 1.3 0.0 0.0 0.0 1.3 1131.8 0.2 0.0 0.4 0.0 1.3 0.0 0.0 0.1 23.9 0.0 0.1 1.4 0.0 457.2 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 4544.5 0.0 0.0 0.0 3.8 0.0 0.0 0.0 2053.3 0.0 0.0 0.0 0.1 0.1 4.0 0.0 0.0 31.2 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 2.1 2.6 1.9 2.8 2.7 2.8 3.0 1.4 4.0 1.5 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.0 0.0 11.9 0.1 0.0 9746.1 0.0 0.0 0.0 20.9 0.1 0.0 0.0 1.9 0.0 5.0 0.0 0.1 69.2 0.0 0.0 0.2 0.2 4.3 315.2 0.0 0.0 0.0 0.1 0.4 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 63.4 86.5 1.0 0.7 0.0 0.4 0.3 0.1 0.1 0.0 0.0 ACTG2 "ACTA3, ACTL3, ACTSG" ENSG00000163017 "Actin gamma 2, smooth muscle" P63267 2 73892314-73919865 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8846.3;seminal vesicle: 6238.4;smooth muscle: 8607.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 394.2;Smooth muscle cells: 287.8" "Cancer enhanced" "Detected in all" "prostate cancer: 255.0;stomach cancer: 237.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "T-reg: 8.6" "Lineage enriched" "Detected in single" 17 "T-cells: 8.6" "Cell line enhanced" "Detected in many" "BEWO: 63.8;BJ hTERT+: 53.5;BJ hTERT+ SV40 Large T+: 214.8;HHSteC: 55.1;SuSa: 52.5;U-251 MG: 229.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 11.8;spinal cord: 4.7" "HPA041264, HPA041271" Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (5.79e-3)" "unprognostic (2.25e-1)" "unprognostic (2.36e-2)" "unprognostic (2.91e-1)" "unprognostic (4.56e-3)" "unprognostic (2.50e-1)" "unprognostic (8.05e-2)" "unprognostic (6.53e-2)" "unprognostic (4.48e-2)" "unprognostic (2.93e-1)" "unprognostic (7.23e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.95e-7)" "unprognostic (9.30e-3)" "unprognostic (6.84e-2)" "unprognostic (2.29e-2)" "unprognostic (7.57e-3)" 189.6 37.1 2.8 724.8 3.9 0.0 138.2 2.8 10.0 494.7 4.8 8846.3 392.1 3622.6 124.6 1954.7 857.3 330.4 30.4 2.9 2.9 11.3 10.8 137.5 6.8 3.4 3.1 88.5 8.1 0.9 6.1 96.4 3.1 2250.2 1179.0 0.0 75.1 6238.4 16.3 91.8 1353.8 8607.9 2.9 16.6 2099.7 4.8 3.1 2.8 33.8 6.9 1.2 2914.5 667.3 2.8 0.7 0.3 20.5 0.3 0.0 0.0 63.8 13.5 53.5 214.8 38.6 6.7 0.0 0.3 0.9 0.0 0.4 0.1 36.9 0.0 28.3 0.1 0.0 0.0 2.9 0.5 55.1 0.2 0.6 0.5 0.3 29.0 0.0 1.5 0.0 0.2 0.0 0.0 0.5 0.0 2.9 7.9 0.2 0.0 0.1 0.2 0.4 3.1 0.5 13.6 0.6 2.3 0.3 2.8 1.2 52.5 0.0 0.3 0.0 1.1 2.3 2.5 229.9 0.1 0.3 0.8 0.7 1.0 0.9 0.2 0.5 0.3 0.2 0.3 0.1 0.1 0.8 0.3 0.4 0.1 0.4 0.5 0.1 0.2 0.4 0.1 8.6 2.4 2.8 3.9 2.8 10.0 2.9 2.9 3.4 3.1 3.1 2.9 3.1 2.8 3.5 0.0 0.5 0.0 0.4 4.5 2.7 0.5 0.6 0.0 9.8 394.2 14.6 0.0 0.1 0.0 0.0 7.4 0.7 0.0 0.0 0.0 5.8 2.8 1.5 3.1 0.0 0.0 0.1 0.0 36.8 74.1 0.0 4.8 0.0 1.0 22.9 0.3 5.4 0.0 0.1 0.0 0.0 0.0 10.4 26.6 0.3 1.0 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 10.8 0.0 0.4 0.8 0.0 6.6 1.8 287.8 0.2 3.2 0.4 7.7 6.4 1.7 8.4 0.0 3.7 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951699-51997078 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026126, HPA063761" Approved Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB026126: , HPA063761: AB_2685115" "unprognostic (8.66e-2)" "unprognostic (5.72e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-3)" "unprognostic (2.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.68e-2)" "unprognostic (5.29e-2)" "unprognostic (2.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.52e-2)" "unprognostic (9.02e-2)" "unprognostic (6.60e-2)" "unprognostic (8.96e-2)" "unprognostic (4.79e-2)" 16.5 10.3 20.7 10.0 20.8 13.5 13.2 13.6 23.4 13.9 9.1 24.6 28.2 8.8 18.0 20.9 15.3 12.2 10.1 21.5 13.3 34.3 29.9 14.7 6.4 12.5 13.9 9.4 40.7 52.7 14.7 11.1 13.1 14.0 24.4 17.4 32.8 15.3 13.1 45.6 26.1 8.1 9.5 8.8 24.9 15.7 16.1 7.6 11.4 8.8 7.4 12.6 18.8 18.3 11.4 24.3 18.6 10.3 20.9 16.2 10.5 12.6 14.2 13.1 9.9 49.5 17.1 5.0 17.2 13.8 14.6 19.6 17.8 15.2 13.5 7.3 21.0 12.3 5.9 15.6 23.8 19.9 43.8 32.0 19.4 14.8 18.6 13.9 18.7 17.7 13.3 14.9 11.8 23.2 19.1 17.2 18.0 24.0 8.5 10.2 14.4 6.4 37.2 17.0 23.5 19.5 13.6 19.2 9.0 13.1 21.1 12.8 12.0 9.0 13.6 10.2 6.1 9.0 6.8 6.7 9.7 9.4 11.8 2.5 1.2 3.9 0.3 1.8 0.5 0.0 0.3 0.3 0.7 0.2 0.8 0.4 1.0 0.0 2.2 0.3 0.5 0.3 20.7 20.8 13.6 23.4 21.5 13.3 12.5 13.9 13.1 9.5 16.1 18.3 8.0 3.2 13.4 8.1 2.9 18.6 10.1 9.2 23.3 45.3 11.3 8.6 5.9 17.2 12.0 25.8 29.2 0.7 2.0 49.7 3.9 17.7 2.9 12.3 8.1 10.9 24.6 0.8 34.8 14.4 0.8 12.6 19.9 9.0 11.4 9.4 17.9 24.4 4.0 37.0 30.2 28.7 2.0 16.7 5.3 8.4 9.9 10.0 7.2 9.4 10.1 8.8 1.0 21.6 11.3 13.3 22.1 9.4 2.3 15.1 31.8 17.0 15.8 24.5 6.6 17.5 12.2 3.8 16.5 17.7 25.3 0.5 4.6 5.6 24.7 15.5 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.5;Inhibitory neurons: 63.4;Oligodendrocyte precursor cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 26.3;RH-30: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 7.3 4.0 6.2 4.6 7.4 3.3 7.0 10.8 6.4 5.4 1.0 6.3 7.7 5.2 6.6 7.2 4.5 7.7 3.7 7.5 7.5 5.6 7.4 4.6 3.1 2.6 4.5 4.5 4.4 4.3 3.9 7.7 3.9 6.8 6.5 8.3 7.5 5.2 17.5 19.5 9.3 7.0 3.8 4.0 6.8 6.4 8.6 2.3 6.7 6.3 3.9 7.4 7.4 4.6 1.8 2.1 13.2 5.0 7.3 4.7 5.4 4.1 5.0 6.9 12.0 5.8 8.1 0.1 3.6 6.7 2.5 6.2 12.0 6.1 8.8 1.4 7.3 0.9 3.6 10.2 26.3 1.0 0.9 8.1 7.3 4.5 8.9 5.2 5.3 1.6 2.0 3.5 4.7 4.8 0.4 0.8 14.9 5.5 3.6 0.2 23.3 1.3 5.6 11.5 13.0 7.3 3.5 4.2 5.4 5.6 2.5 1.4 4.1 6.4 7.5 6.1 2.9 1.0 0.3 2.4 3.9 0.5 5.2 0.2 1.7 0.2 0.6 2.0 0.2 0.1 2.4 1.1 1.3 0.3 1.5 0.3 0.0 4.8 2.0 1.7 0.2 0.7 6.2 7.4 10.8 6.4 7.5 7.5 2.6 4.5 3.9 3.8 8.6 4.6 13.7 6.4 7.0 26.8 1.5 29.7 6.9 9.5 13.1 15.4 6.8 12.4 7.9 17.2 10.7 7.3 14.6 4.9 6.0 16.5 1.9 6.3 5.3 6.4 12.2 11.9 9.0 0.0 62.5 6.3 2.5 17.4 6.6 5.7 0.0 2.2 11.7 12.1 5.4 11.8 63.4 12.9 8.2 7.3 18.9 2.1 9.9 5.7 10.6 33.7 7.2 3.3 6.2 84.9 34.1 7.6 10.0 11.3 5.2 7.7 23.7 5.8 10.2 9.4 32.9 8.3 10.9 18.2 14.1 14.4 29.8 5.3 5.9 2.9 11.7 11.8 ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983340-51989197 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "intestine: 181.5;kidney: 449.9;liver: 274.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.6;Gastric mucus-secreting cells: 32.6;Proximal enterocytes: 144.8;Proximal tubular cells: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 128.0" "CAB003695, HPA036174, HPA036175" Enhanced NA NA 23000000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB003695: AB_425286, HPA036174: AB_2674988, HPA036175: AB_2674989" "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-3)" "unprognostic (3.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.08e-2)" "unprognostic (2.36e-2)" "unprognostic (2.70e-2)" "prognostic favorable (2.93e-4)" "unprognostic (3.57e-1)" "unprognostic (3.75e-1)" "unprognostic (7.88e-2)" "prognostic favorable (6.77e-4)" 19.2 24.0 5.6 7.3 5.7 8.8 20.7 6.4 7.3 13.9 11.6 30.6 181.5 4.3 21.8 10.7 13.0 10.7 14.5 5.1 6.0 449.9 274.9 9.2 7.2 6.5 5.9 4.8 8.7 28.2 4.7 9.7 6.6 14.3 30.5 1.9 16.4 11.1 20.2 8.2 138.2 6.9 6.7 8.1 23.6 3.2 6.1 5.1 21.0 34.6 9.2 12.5 7.1 6.6 15.9 26.2 13.2 34.1 28.9 39.4 40.5 12.6 28.2 29.4 14.9 41.2 67.9 7.2 12.2 22.0 13.2 20.0 14.7 81.2 11.5 21.8 10.7 25.3 13.9 128.0 49.7 19.8 21.0 48.0 67.2 25.4 69.1 25.8 11.5 14.6 47.1 23.9 29.9 35.2 0.6 38.9 23.4 92.1 39.3 8.0 14.1 63.5 74.5 50.8 16.9 18.2 12.6 62.6 29.5 7.5 42.3 27.9 7.1 22.0 21.9 24.8 18.8 61.7 16.9 12.1 28.1 42.9 29.0 9.1 15.7 0.4 10.7 15.1 5.7 7.4 2.6 4.5 21.2 6.1 4.1 4.7 0.0 20.4 6.4 2.8 3.8 9.7 5.6 5.7 6.4 7.3 5.1 6.0 6.5 5.9 6.6 6.7 6.1 6.6 0.5 3.2 3.2 0.0 4.9 0.6 1.0 1.9 17.1 0.2 2.7 1.3 0.2 1.5 2.5 5.5 0.0 3.9 0.3 31.6 9.8 16.6 0.2 0.2 0.9 0.9 2.4 15.8 0.0 8.3 4.5 4.3 32.6 0.6 7.0 0.2 1.1 13.1 1.9 0.0 0.0 11.2 4.1 1.9 0.3 0.8 0.6 4.2 0.0 0.0 9.3 0.8 1.0 0.0 0.0 16.4 23.3 0.0 14.9 0.6 144.8 92.0 1.7 1.1 0.0 0.6 2.0 0.1 0.2 18.5 0.4 4.1 2.6 1.0 14.5 0.4 ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0;ovary: 10.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 7.3;Excitatory neurons: 44.7;Fibroblasts: 13.7;Granulosa cells: 22.2;Theca cells: 15.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;SuSa: 3.5;U-2197: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067668 Approved "Nucleoplasm,Nuclear membrane,Midbody ring,Mitochondria" "Secreted to extracellular matrix" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" "Nucleoplasm, Midbody ring" "HPA067668: " "unprognostic (8.48e-2)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (5.04e-2)" "unprognostic (7.64e-2)" "unprognostic (7.80e-3)" "unprognostic (2.12e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-2)" "unprognostic (2.18e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (4.59e-3)" "unprognostic (2.86e-3)" 5.4 0.2 1.4 0.4 1.9 0.5 0.7 17.0 2.6 1.4 0.0 0.7 0.6 1.3 1.6 1.5 0.7 6.4 0.2 3.4 0.0 3.5 0.4 0.7 0.2 0.2 0.2 10.4 4.5 0.1 0.0 0.2 0.7 0.1 0.3 1.2 0.2 0.5 0.2 0.4 0.5 1.1 0.0 0.2 0.2 0.4 0.0 0.2 0.3 0.2 0.1 1.0 0.6 1.8 1.7 1.7 1.7 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.5 0.0 1.4 0.1 2.1 0.0 3.0 0.1 0.0 0.0 0.4 0.1 0.9 0.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 3.9 0.1 0.5 0.0 0.3 0.6 0.4 0.7 0.0 0.4 0.2 1.1 0.0 1.6 0.4 2.2 0.1 0.0 0.1 0.5 0.1 0.1 0.1 0.1 3.5 0.1 0.1 0.1 2.1 3.0 5.8 1.4 0.9 0.3 0.1 3.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 1.9 17.0 2.6 3.4 0.0 0.2 0.2 0.7 0.0 0.0 1.8 0.7 0.0 0.6 2.6 0.0 0.0 0.0 0.0 0.6 2.0 0.7 0.4 0.5 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.2 5.0 0.1 0.0 0.0 44.7 0.0 0.0 13.7 0.5 0.5 0.0 22.2 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 1.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 6.9 1.6 0.1 0.0 0.0 0.0 0.0 0.1 15.9 0.0 0.0 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADCY8 "AC8, ADCY3, HBAC1" ENSG00000155897 "Adenylate cyclase 8" P40145 8 130780301-131040909 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 29.4;epididymis: 22.8" "Group enriched" "Detected in some" 5 "Astrocytes: 151.8;Inhibitory neurons: 250.9;Oligodendrocyte precursor cells: 138.7" "Group enriched" "Detected in some" 5 "glioma: 6.0;ovarian cancer: 1.8;thyroid cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.0;GAMG: 8.2;U-138 MG: 17.6;U-87 MG: 34.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018652, HPA024291" Supported NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB018652: AB_633654, HPA024291: AB_1844597" "unprognostic (5.59e-3)" "unprognostic (3.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "unprognostic (8.22e-3)" "unprognostic (4.91e-2)" "unprognostic (7.39e-3)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" "unprognostic (6.67e-2)" 0.0 0.0 17.0 0.0 13.4 0.0 0.5 19.7 9.6 0.4 1.7 0.0 0.0 0.0 22.8 0.0 3.9 0.0 0.0 11.9 14.0 0.2 0.0 1.2 0.0 17.2 22.6 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 3.1 1.1 1.4 0.1 2.1 0.0 0.5 25.9 0.0 0.1 0.5 29.4 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.1 1.3 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 17.6 0.4 0.0 0.0 0.0 0.0 0.0 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 13.4 19.7 9.6 11.9 14.0 17.2 22.6 15.2 25.9 29.4 23.3 0.0 0.0 1.5 151.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 32.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 250.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.4 0.0 0.1 0.0 138.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADGRF2 "GPR111, hGPCR35, PGR20" ENSG00000164393 "Adhesion G protein-coupled receptor F2" Q8IZF7 6 47656436-47697797 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "fallopian tube: 1.0;skin 1: 2.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Early spermatids: 1.0;Endometrial ciliated cells: 1.6;Excitatory neurons: 1.2;Glandular and luminal cells: 1.3;Squamous epithelial cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035507 Uncertain NA NA "Cluster 31: Skin - Epidermis development" "Cluster 44: Endometrium - Transcription" "HPA035507: AB_10601809" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (3.74e-2)" "unprognostic (5.95e-1)" "unprognostic (1.59e-1)" "unprognostic (1.53e-1)" "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" "unprognostic (2.51e-4)" "unprognostic (3.05e-2)" "unprognostic (3.86e-2)" "unprognostic (1.20e-1)" "unprognostic (2.24e-1)" "unprognostic (7.99e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 1.6 0.1 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 71.9;placenta: 47.4" "Cell type enhanced" "Detected in many" "Endothelial cells: 41.7;Hepatocytes: 143.8;Kupffer cells: 40.5;Pancreatic endocrine cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 88.6;Hep G2: 84.8;hTERT-HME1: 81.5;HUVEC TERT2: 161.4;MCF7: 155.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017346 Approved NA NA 110000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA017346: AB_1849260" "unprognostic (1.04e-2)" "unprognostic (2.72e-2)" "unprognostic (7.37e-2)" "unprognostic (3.00e-2)" "unprognostic (8.64e-4)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.46e-1)" "unprognostic (6.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.97e-2)" "unprognostic (4.59e-2)" 5.8 2.8 2.6 4.1 2.3 0.4 5.2 1.6 1.9 3.0 1.9 6.2 17.5 1.1 1.3 11.6 5.2 8.3 4.0 1.8 1.7 7.2 71.9 15.2 1.7 2.4 2.9 1.4 3.2 1.3 0.3 47.4 2.2 3.2 6.4 0.1 9.0 6.5 0.5 14.5 10.2 2.2 2.5 7.5 12.3 2.1 4.6 4.6 1.6 1.2 4.0 15.1 5.6 1.9 17.0 88.6 1.9 9.4 0.5 0.0 0.2 23.1 4.3 17.2 10.7 71.3 51.0 0.0 20.3 13.4 4.9 41.3 2.6 22.1 28.3 0.0 6.8 3.6 14.5 84.8 16.7 14.6 0.0 0.1 34.9 0.4 81.5 10.0 161.4 0.4 0.6 0.1 6.9 155.6 0.3 0.0 0.7 6.2 20.0 0.0 7.7 17.7 9.0 37.9 0.1 0.1 6.8 30.8 14.5 14.1 16.7 0.3 5.6 0.1 7.6 7.7 11.5 0.0 0.1 0.0 0.1 0.1 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.3 1.6 1.9 1.8 1.7 2.4 2.9 2.2 2.5 4.6 1.9 5.1 6.4 5.9 0.0 0.3 0.0 21.9 0.0 18.8 0.0 5.3 2.7 1.9 24.3 8.1 9.2 0.0 5.3 0.0 0.6 0.0 13.2 0.1 0.1 0.5 41.7 0.0 17.0 1.6 5.4 33.5 14.5 32.1 0.5 0.0 0.0 27.1 143.8 2.2 0.0 12.7 3.5 0.0 40.5 0.0 0.6 0.6 8.1 0.0 15.0 0.9 0.0 0.0 0.5 0.3 37.9 8.8 0.4 0.1 18.7 9.5 11.8 2.9 0.0 6.6 0.4 1.3 2.6 5.3 30.2 0.0 13.5 1.6 0.0 1.7 25.0 ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61201258-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3" "Group enriched" "Detected in many" 11 "Astrocytes: 584.1;Excitatory neurons: 696.1;Inhibitory neurons: 737.4;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 592.1" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 41.8;EFO-21: 10.8;HEK 293: 6.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" 7.1 6.2 25.1 1.1 25.7 0.0 2.5 14.0 30.7 5.5 0.0 4.0 2.5 3.9 1.8 1.0 2.4 1.6 2.6 30.4 25.0 1.6 0.4 2.6 0.4 15.3 24.6 1.1 0.3 6.7 0.9 1.2 15.9 1.3 3.9 10.0 0.6 4.2 0.7 3.0 3.6 3.0 12.5 0.3 3.2 4.1 32.3 0.4 0.7 0.3 0.1 1.6 3.4 15.7 0.0 0.1 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 3.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 1.0 0.0 4.0 0.5 0.1 0.1 0.0 4.8 0.2 0.0 6.3 0.3 0.0 0.0 0.0 7.6 0.1 3.2 0.0 0.2 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 25.7 14.0 30.7 30.4 25.0 15.3 24.6 15.9 12.5 32.3 15.7 0.4 0.0 0.0 584.1 0.0 0.0 0.0 0.0 0.6 12.4 4.9 1.8 3.3 0.0 0.0 0.0 4.2 1.0 0.0 0.0 9.8 0.0 46.4 1.3 17.7 1.9 0.0 0.0 696.1 0.0 1.3 3.3 0.0 0.4 0.0 0.4 2.5 0.2 0.1 1.7 737.4 0.0 0.0 0.0 0.0 33.2 0.0 0.5 0.0 70.3 0.0 31.3 0.0 1300.8 592.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.4 6.6 0.3 18.5 0.9 3.5 1.2 0.0 2.2 0.2 0.1 0.0 0.1 ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Group enriched" "Detected in many" 5 "Adipocytes: 559.9;Endothelial cells: 276.0;Hepatic stellate cells: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 101.2;HUVEC TERT2: 330.0;TIME: 379.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" 73.1 8.2 7.7 9.7 8.2 0.7 64.0 8.5 13.8 22.1 7.0 9.3 4.7 16.3 6.2 9.0 12.1 22.4 24.2 8.0 8.0 15.2 14.3 18.0 9.9 9.1 7.7 4.8 4.7 9.7 5.1 22.5 9.1 9.4 6.3 3.0 7.9 8.9 14.2 9.0 8.6 27.6 7.6 39.8 8.0 6.7 9.8 4.6 20.8 23.6 7.1 24.0 10.4 8.4 0.0 0.0 25.7 0.2 7.3 24.7 0.0 7.8 7.7 0.5 0.3 0.8 0.2 0.2 0.6 22.5 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.5 0.7 0.1 25.3 0.0 0.3 17.8 0.4 55.7 0.3 101.2 330.0 0.2 0.4 2.5 7.0 0.0 0.0 1.0 0.4 0.2 0.4 0.2 0.0 0.0 61.1 3.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 379.3 0.2 5.8 2.0 0.0 0.8 0.5 0.1 0.3 0.5 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 8.2 8.5 13.8 8.0 8.0 9.1 7.7 9.1 7.6 9.8 8.4 559.9 0.0 6.0 0.3 1.2 0.0 0.4 0.0 4.6 0.0 1.8 2.5 7.6 5.7 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 45.3 0.8 1.5 276.0 0.0 2.7 1.5 0.2 0.0 10.2 0.0 3.8 0.0 0.0 287.7 3.5 0.6 1.7 1.0 0.0 0.0 19.2 0.0 57.9 0.6 1.5 0.0 72.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.4 1.2 1.3 0.0 0.0 0.0 0.4 0.0 5.1 5.7 7.2 1.8 1.0 0.0 0.0 1.1 5.4 0.0 0.7 ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "adrenal gland: 533.0" "Cell type enriched" "Detected in many" 8 "Astrocytes: 2207.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 15.5;HAP1: 23.0;K-562: 9.8;NTERA-2: 11.6;SCLC-21H: 11.1;SuSa: 15.0;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" 0.0 533.0 36.9 0.0 47.8 0.6 3.6 12.7 40.3 0.9 22.4 1.0 0.3 0.1 0.7 2.4 0.2 12.3 0.2 39.1 11.6 21.5 42.3 2.1 0.0 9.4 12.8 0.2 1.5 0.8 15.1 4.1 9.4 1.3 1.0 18.2 2.3 0.2 0.2 2.1 0.5 0.0 7.3 0.3 1.1 1.4 18.3 0.8 17.5 0.0 0.4 10.4 1.9 26.1 0.5 2.1 15.5 0.0 0.0 0.1 0.2 0.3 0.1 0.0 0.0 1.7 0.2 0.3 0.4 0.0 0.4 0.2 23.0 0.2 0.0 1.0 4.3 4.1 2.0 1.4 0.0 0.3 0.1 0.0 4.8 0.0 0.1 0.1 0.0 0.1 9.8 2.6 0.0 2.1 0.1 0.2 11.6 2.9 4.2 0.0 0.4 2.1 0.0 0.5 11.1 2.7 3.4 2.2 0.2 15.0 5.9 0.0 0.8 0.4 1.9 0.5 1.1 13.4 4.1 0.6 0.7 0.2 0.0 3.2 0.9 2.8 1.0 0.7 1.7 1.5 1.1 1.4 0.5 2.9 1.7 0.9 4.6 1.1 0.5 1.2 1.6 0.2 36.9 47.8 12.7 40.3 39.1 11.6 9.4 12.8 9.4 7.3 18.3 26.1 0.4 25.6 26.5 2207.3 0.0 0.0 6.1 0.0 1.8 28.0 15.5 7.4 2.4 2.8 5.6 5.5 264.8 3.0 0.4 0.6 1.9 1.9 43.5 3.3 0.3 1.1 7.3 0.0 54.0 4.2 2.6 1.1 4.6 1.9 0.0 6.7 0.0 12.4 0.2 10.1 21.9 0.4 0.0 0.8 0.0 54.8 0.6 0.5 0.0 51.5 1.2 8.9 1.0 40.2 7.4 1.7 1.2 0.4 0.1 2.1 0.1 24.2 7.3 84.4 0.0 0.3 0.4 3.6 4.5 2.9 0.0 4.1 0.6 0.2 1.2 9.0 ADIPOQ "ACDC, ACRP30, adiponectin, apM1, GBP28" ENSG00000181092 "Adiponectin, C1Q and collagen domain containing" Q15848 3 186842704-186858463 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hormone "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 28 "adipose tissue: 898.8;breast: 248.9" "Cell type enhanced" "Detected in single" "Distal tubular cells: 1.9" "Group enriched" "Detected in some" 8 "breast cancer: 6.5;pancreatic cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 672 "ASC diff: 312.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB046467, HPA051767" Uncertain "Secreted to blood" NA NA 8360000000 910000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB046467: AB_1078104, HPA051767: AB_2681598" "unprognostic (1.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.20e-2)" "unprognostic (6.99e-3)" "unprognostic (1.87e-1)" 898.8 8.9 0.1 2.4 0.1 0.2 248.9 0.2 0.1 0.0 0.0 7.7 0.1 0.1 0.0 1.2 0.1 7.6 6.5 0.0 0.0 0.8 0.1 0.1 1.3 0.1 0.0 0.0 6.2 0.1 0.1 0.0 0.1 0.3 6.1 0.1 18.8 0.0 2.3 6.6 8.5 1.2 0.0 0.0 3.9 0.1 0.1 2.2 2.9 20.2 0.0 2.4 0.9 0.3 0.0 0.0 0.0 0.1 312.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADIPOR1 "ACDCR1, PAQR1" ENSG00000159346 "Adiponectin receptor 1" Q96A54 1 202940826-202958572 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 329.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 28: BEWO - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (3.81e-2)" "unprognostic (2.74e-1)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (9.95e-2)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.27e-4)" "prognostic unfavorable (5.50e-4)" "unprognostic (1.13e-1)" "unprognostic (1.79e-3)" "unprognostic (5.90e-2)" "unprognostic (1.75e-1)" "unprognostic (2.84e-1)" "unprognostic (8.63e-2)" 59.8 58.5 56.1 49.1 60.1 215.2 63.6 58.7 64.2 55.4 82.9 55.6 46.5 40.9 91.4 110.9 68.6 48.2 92.6 56.8 57.7 70.4 106.2 80.5 48.0 61.2 58.6 47.7 91.7 107.1 45.5 100.0 60.2 53.7 59.8 135.6 106.6 47.4 136.5 110.8 47.4 50.9 60.1 65.8 63.3 48.7 58.7 50.2 56.6 140.2 77.9 70.9 69.2 65.2 97.0 87.2 53.4 59.9 111.4 85.4 276.8 103.4 123.9 108.8 99.4 88.7 114.7 63.5 75.3 120.6 86.3 118.0 81.3 145.5 96.5 118.5 93.5 48.6 104.3 72.6 109.7 101.6 71.6 101.7 235.0 115.9 118.3 108.4 108.8 111.7 128.1 133.5 111.2 105.6 85.3 77.4 119.7 87.1 103.1 66.7 128.7 125.7 106.5 111.0 89.2 90.8 109.6 166.5 135.5 143.6 121.1 99.4 95.7 78.9 62.2 39.4 117.3 137.8 197.4 71.4 113.5 58.9 94.5 362.2 361.8 455.4 136.0 253.6 143.8 157.9 143.4 134.1 209.8 165.2 141.5 124.3 825.9 126.0 259.6 146.1 179.5 557.4 56.1 60.1 58.7 64.2 56.8 57.7 61.2 58.6 60.2 60.1 58.7 65.2 40.7 35.3 52.5 6.8 46.8 235.0 95.2 109.8 75.7 24.8 81.9 54.2 59.7 32.9 79.3 53.3 29.2 112.7 42.8 49.3 68.4 73.8 68.2 58.8 24.5 53.4 49.1 329.0 13.7 86.3 172.4 40.9 37.2 54.3 37.3 18.8 58.5 60.8 104.2 11.8 15.1 49.1 85.5 148.5 89.7 62.5 28.6 107.6 85.4 15.9 85.0 38.0 42.2 9.5 20.0 120.0 43.5 24.5 116.0 133.1 67.3 65.9 82.5 54.9 39.5 29.2 61.7 26.4 27.2 79.3 228.9 202.8 47.1 29.2 41.7 206.6 ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8;testis: 21.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 18.1;granulocytes: 22.3;Muller glia cells: 44.4;Oligodendrocyte precursor cells: 35.2;Oligodendrocytes: 31.5" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 40.3;MCF7: 24.4;RH-30: 65.4;RPTEC TERT1: 31.7;SK-BR-3: 35.2;U-138 MG: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA044383: AB_2678921" "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" 3.7 0.2 31.9 1.6 34.6 0.0 4.6 28.6 33.8 1.0 0.0 1.0 1.0 1.2 0.6 1.1 1.2 0.9 11.4 29.6 23.0 9.3 0.4 1.7 0.6 35.7 35.0 0.3 13.2 8.0 1.9 6.8 41.8 1.0 0.6 4.8 6.4 0.4 1.7 4.6 1.2 0.4 23.6 6.3 1.0 21.4 54.8 0.4 2.2 2.5 0.5 1.6 0.7 41.5 0.3 3.0 0.6 0.2 0.2 1.6 0.2 2.0 3.0 0.7 0.4 40.3 0.7 0.0 8.9 7.3 4.8 0.1 0.7 0.0 0.2 0.0 1.1 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.9 0.0 6.4 0.0 6.4 0.0 0.1 6.2 24.4 0.1 0.0 10.2 0.0 0.0 0.0 65.4 2.3 31.7 0.0 0.8 0.7 4.4 35.2 0.5 3.6 2.0 1.0 0.0 20.9 10.6 0.0 11.7 0.0 0.2 0.0 10.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 34.6 28.6 33.8 29.6 23.0 35.7 35.0 41.8 23.6 54.8 41.5 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 1.1 9.4 6.9 3.1 7.2 0.0 3.7 0.0 0.1 0.1 0.1 0.0 11.7 0.1 0.0 0.4 0.3 0.0 0.0 18.1 3.3 1.3 1.1 0.0 0.1 22.3 0.8 0.0 0.0 0.9 0.0 2.9 0.0 0.0 1.0 1.0 0.5 0.0 0.6 1.8 1.9 0.2 44.4 0.0 35.2 31.5 0.5 0.0 0.7 0.0 0.0 0.0 3.0 0.0 1.6 0.0 0.0 0.6 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 ADORA2B ENSG00000170425 "Adenosine A2b receptor" P29275 17 15944917-15975746 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7;urinary bladder: 14.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 73.5;Basal respiratory cells: 75.6;Langerhans cells: 31.9;Suprabasal keratinocytes: 64.4;Urothelial cells: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9;myeloid DC: 9.0" "Group enriched" "Detected in many" 97 "dendritic cells: 9.0;granulocytes: 14.9;monocytes: 5.0" "Cell line enhanced" "Detected in many" "GAMG: 160.8;HMC-1: 162.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073747 Uncertain Cytosol NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA073747: " "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (4.68e-1)" "unprognostic (7.88e-3)" "unprognostic (2.64e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "unprognostic (1.38e-1)" "unprognostic (1.66e-9)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.84e-1)" 0.5 1.1 7.5 1.7 9.4 0.8 0.7 7.0 11.7 2.4 9.0 8.6 0.2 0.7 0.5 9.1 0.9 1.1 1.6 9.1 7.3 0.3 0.1 1.9 0.3 7.7 7.7 0.0 1.3 0.0 1.4 5.0 7.1 1.3 6.6 2.8 1.4 0.1 0.1 8.5 1.3 1.3 6.4 0.2 1.2 0.3 8.3 0.4 0.1 0.5 1.3 14.2 5.2 8.2 34.1 18.3 0.6 0.7 5.8 11.1 0.7 6.4 28.4 18.3 22.6 8.8 34.6 4.4 7.8 5.7 160.8 51.9 7.9 47.8 24.2 9.7 18.0 32.7 5.8 13.0 22.3 0.0 162.6 6.5 20.1 26.0 60.4 31.3 9.3 5.1 1.6 0.1 18.2 8.9 2.2 6.6 1.9 72.0 25.5 0.1 0.4 0.0 19.1 9.1 0.8 1.2 14.3 3.4 9.0 13.4 0.1 5.1 7.7 6.5 17.1 18.3 30.3 2.8 0.0 0.0 25.8 0.0 9.2 14.9 4.2 2.8 0.0 5.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.4 0.0 2.6 0.1 0.0 1.7 7.5 9.4 7.0 11.7 9.1 7.3 7.7 7.7 7.1 6.4 8.3 8.2 0.1 3.2 4.2 18.9 0.2 73.5 21.0 75.6 27.3 0.2 1.3 1.9 0.9 1.5 20.2 0.0 0.0 10.9 0.1 10.8 0.0 6.6 0.9 0.9 0.6 1.7 2.4 3.4 0.9 0.9 3.2 4.9 2.0 1.2 0.0 0.1 2.2 0.0 4.5 0.0 1.1 1.7 2.0 1.4 31.9 0.4 0.0 6.7 7.2 3.7 1.3 7.9 0.0 1.0 1.0 1.0 7.2 0.0 0.0 15.6 0.2 0.0 8.3 0.5 0.0 0.7 2.1 0.5 1.4 23.0 64.4 6.2 0.3 0.3 5.7 32.4 ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.9;Kupffer cells: 79.2;Late spermatids: 18.2;Macrophages: 26.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cell line enriched" "Detected in some" 9 "HMC-1: 108.1" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" 4.5 15.0 8.9 4.3 9.2 0.2 5.5 10.6 14.6 4.4 8.8 6.6 4.5 1.9 0.2 2.5 3.6 5.8 3.4 8.8 12.3 1.6 3.3 3.5 6.4 16.1 11.1 1.8 1.8 3.1 2.6 2.8 14.9 2.4 5.1 1.0 2.8 2.4 0.5 0.9 9.4 4.8 13.5 4.3 3.0 1.2 16.9 3.5 1.4 1.0 2.7 4.3 1.7 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 108.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.0 8.1 601.6 0.0 5.6 0.1 0.2 0.0 0.0 15.0 0.1 0.1 0.1 2.0 0.1 2.1 3.0 0.0 2.5 8.9 9.2 10.6 14.6 8.8 12.3 16.1 11.1 14.9 13.5 16.9 21.8 0.2 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 7.3 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 1.8 0.2 17.9 0.0 0.0 0.0 0.0 79.2 4.4 18.2 0.3 26.3 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.1 0.4 0.0 1.6 0.0 0.0 0.1 ADPRS "ADPRHL2, ARH3, FLJ20446" ENSG00000116863 "ADP-ribosylserine hydrolase" Q9NX46 1 36088892-36093932 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 79.2;Extravillous trophoblasts: 40.7;Hofbauer cells: 51.6;Syncytiotrophoblasts: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026641, HPA027104, HPA027141" Approved Enhanced Nucleoplasm "Intracellular and membrane" NA NA 54000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA026641: , HPA027104: AB_10601330, HPA027141: AB_1844619" "unprognostic (3.22e-3)" "unprognostic (5.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.61e-2)" "unprognostic (5.98e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.10e-7)" "unprognostic (3.71e-2)" "unprognostic (2.63e-1)" "unprognostic (5.34e-2)" "unprognostic (3.17e-2)" "unprognostic (7.80e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (9.31e-2)" "unprognostic (3.65e-2)" "unprognostic (4.74e-2)" 19.0 36.7 28.4 16.0 30.0 19.7 18.5 31.3 30.3 20.7 33.4 19.6 15.6 17.6 15.0 36.1 33.5 13.3 20.7 28.6 29.1 27.7 22.4 20.6 21.5 32.5 29.7 19.7 17.9 17.6 17.7 20.8 31.2 19.9 12.4 9.1 20.9 16.3 34.4 34.1 16.8 16.4 31.9 23.1 17.6 28.7 29.7 20.9 19.4 21.8 20.2 21.3 22.2 33.9 54.3 22.4 26.2 37.2 23.6 17.1 37.3 39.4 32.9 62.1 60.9 26.8 47.7 38.4 37.5 39.5 32.0 32.9 33.4 60.5 37.0 27.7 41.8 34.9 27.0 36.3 44.4 40.2 19.9 20.3 45.4 56.5 24.5 47.2 39.9 36.2 30.8 30.9 29.6 26.0 40.9 60.5 56.5 31.8 46.0 32.9 27.6 38.8 56.5 43.8 32.1 50.8 28.9 29.9 65.9 34.4 30.9 34.3 27.6 35.7 37.0 50.1 53.0 39.8 41.2 34.2 51.7 39.6 22.4 40.6 58.3 65.8 43.4 74.1 41.5 43.5 47.6 50.8 71.4 51.5 47.7 40.3 57.1 47.9 77.7 44.8 43.4 57.8 28.4 30.0 31.3 30.3 28.6 29.1 32.5 29.7 31.2 31.9 29.7 33.9 3.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 79.2 6.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 40.7 6.4 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 70.6 1.3 0.0 0.0 0.0 ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;liver: 60.1" "Cell type enhanced" "Detected in some" "Astrocytes: 105.4;Early spermatids: 51.3;Inhibitory neurons: 123.2;Late spermatids: 28.3;Oligodendrocyte precursor cells: 114.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" 21.8 0.5 13.3 1.1 11.1 0.0 3.6 3.0 22.6 0.7 0.0 1.4 0.9 1.4 0.6 0.8 0.2 0.3 7.6 42.6 20.8 0.7 60.1 3.9 1.7 9.3 4.9 0.9 0.0 0.0 0.1 0.0 9.5 12.4 0.5 0.3 6.2 13.5 0.2 0.6 1.1 2.9 1.5 9.2 0.9 0.1 4.2 0.1 0.1 1.4 0.4 0.4 0.3 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 11.1 3.0 22.6 42.6 20.8 9.3 4.9 9.5 1.5 4.2 6.9 0.0 0.0 0.0 105.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 16.2 0.0 0.0 123.2 0.0 0.0 0.0 0.5 28.3 0.6 0.0 0.0 9.4 0.0 0.0 0.0 114.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 ADTRP "AIG1L, C6orf105, dJ413H6.1" ENSG00000111863 "Androgen dependent TFPI regulating protein" Q96IZ2 6 11712054-11807046 "Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 98.5;parathyroid gland: 92.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 116.4;Distal tubular cells: 52.8;Early spermatids: 141.6;Late spermatids: 168.0;Paneth cells: 87.0;Proximal enterocytes: 127.0;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 14.8;T-reg: 13.5" "Lineage enriched" "Detected in many" 5 "T-cells: 14.8" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 93.9;RPMI-8226: 41.2;TIME: 57.7;U-138 MG: 42.4;U-266/84: 47.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA048113 Uncertain Uncertain Nucleoli NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoli "HPA048113: AB_2680268" "unprognostic (6.82e-3)" "unprognostic (1.41e-1)" "unprognostic (1.58e-1)" "unprognostic (8.14e-3)" "unprognostic (3.04e-3)" "unprognostic (1.41e-2)" "unprognostic (4.00e-2)" "unprognostic (1.77e-1)" "unprognostic (1.85e-2)" "unprognostic (2.72e-1)" "unprognostic (5.41e-3)" "unprognostic (2.90e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (2.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.95e-2)" "unprognostic (1.26e-1)" 0.5 0.2 1.9 14.2 2.1 1.1 3.3 0.6 2.2 0.4 35.2 80.7 82.4 0.3 13.7 1.5 0.6 1.6 0.3 2.0 0.0 9.8 1.4 11.1 9.4 0.1 0.1 0.2 0.8 92.9 0.0 2.4 0.1 0.4 58.5 0.6 0.8 24.4 1.0 18.9 98.5 2.6 0.1 1.3 38.2 22.6 0.4 2.6 0.5 0.1 12.7 10.2 0.3 1.1 4.1 0.0 0.0 0.0 0.5 0.9 0.1 1.5 0.8 1.0 0.7 3.6 1.9 0.1 1.7 0.7 2.4 1.9 0.0 11.2 1.4 0.1 0.0 0.3 0.8 0.1 0.3 0.1 0.2 0.0 20.4 10.4 23.6 17.5 93.9 0.7 23.0 0.0 3.1 0.1 0.2 0.6 0.3 0.1 5.8 0.0 0.3 41.2 1.7 0.2 0.1 0.2 1.5 0.0 0.8 2.8 0.0 0.8 57.7 42.4 2.0 0.7 2.6 1.2 47.1 0.0 7.9 1.3 0.2 2.7 0.0 0.0 0.0 0.3 2.6 0.2 3.7 0.3 0.1 0.2 14.8 1.3 0.3 0.1 0.2 0.2 13.5 1.7 1.9 2.1 0.6 2.2 2.0 0.0 0.1 0.1 0.1 0.1 0.4 1.1 0.2 0.0 1.1 0.7 4.0 5.1 0.3 3.9 0.6 0.0 0.1 1.9 0.1 0.0 2.6 5.5 0.0 0.2 0.1 116.4 52.8 0.7 141.6 0.2 0.0 0.3 5.4 2.7 13.1 2.4 0.2 1.1 32.1 0.1 5.7 0.0 0.0 0.2 11.4 0.0 0.4 40.7 2.0 0.8 1.5 168.0 1.8 3.1 1.8 0.0 27.9 0.0 1.0 1.0 0.1 7.9 87.0 0.7 7.8 0.6 127.0 0.7 0.8 0.0 0.0 0.2 1.2 1.6 0.7 0.4 5.7 0.1 6.2 0.0 52.3 0.5 AEBP2 MGC17922 ENSG00000139154 "AE binding protein 2" Q6ZN18 12 19404045-19720801 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020893, HPA022282" Uncertain Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA020893: AB_2670528, HPA022282: AB_2670931" "unprognostic (3.28e-1)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (3.16e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (9.15e-2)" "unprognostic (4.56e-2)" "unprognostic (5.19e-3)" "unprognostic (1.87e-1)" "unprognostic (3.45e-2)" "unprognostic (1.68e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-1)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" 19.0 27.2 9.9 20.0 11.6 20.5 23.5 13.0 16.5 25.8 12.5 18.8 16.3 34.0 20.2 35.1 28.0 21.8 17.8 17.7 7.2 27.8 20.3 20.7 27.7 1.9 6.7 35.1 17.5 29.9 8.9 44.1 2.0 24.8 20.6 27.7 19.3 30.7 13.6 29.4 16.7 31.1 0.3 23.1 16.1 20.8 11.8 29.2 30.8 19.8 32.3 25.0 18.2 14.7 32.4 42.4 42.6 20.1 31.1 38.6 95.2 29.9 34.1 43.5 45.7 48.0 54.5 51.0 24.3 41.4 27.6 38.0 93.7 34.6 69.1 149.4 30.6 46.7 60.8 30.0 36.4 60.1 30.8 36.2 36.3 35.6 52.8 52.0 35.6 34.8 25.2 1.4 41.2 38.5 63.0 71.7 82.6 26.6 18.9 50.3 82.3 35.9 32.2 68.2 10.0 23.4 60.6 25.7 29.8 91.3 32.8 35.0 40.5 40.7 30.9 12.8 44.9 14.0 24.9 106.0 30.3 25.1 29.2 4.3 2.5 2.5 4.2 2.7 4.4 2.2 4.4 3.6 2.0 2.8 3.7 5.8 2.7 6.0 2.2 2.6 4.5 1.2 9.9 11.6 13.0 16.5 17.7 7.2 1.9 6.7 2.0 0.3 11.8 14.7 23.9 25.6 14.3 31.6 20.5 75.2 25.1 15.5 53.5 29.8 22.0 13.3 22.1 12.8 24.2 12.9 43.8 60.3 24.3 9.5 17.6 12.3 1.3 31.1 31.5 22.2 22.7 11.6 57.2 12.2 24.8 28.3 14.3 28.8 27.8 17.7 14.3 12.9 15.4 52.2 59.4 11.2 4.1 17.0 47.9 2.3 24.5 17.8 28.4 30.0 17.7 21.5 14.4 42.3 51.6 11.5 10.3 29.0 18.3 24.5 9.0 18.3 26.1 16.1 19.7 46.7 40.1 16.2 26.3 51.0 76.0 83.0 28.1 34.2 10.7 28.2 AFAP1 "AFAP, AFAP-110" ENSG00000196526 "Actin filament associated protein 1" Q8N556 4 7758714-7939926 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 170.5;Extravillous trophoblasts: 116.3;Inhibitory neurons: 117.2;Late spermatids: 373.8;Oligodendrocyte precursor cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.9" "Group enriched" "Detected in many" 5 "granulocytes: 2.9;T-cells: 1.2" "Cell line enhanced" "Detected in many" "TIME: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015642, CAB024712" Enhanced Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Actin filaments, Cytosol" "Focal adhesion sites" "CAB024712: , HPA015642: AB_1844632" "unprognostic (1.12e-1)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.00e-1)" "unprognostic (3.39e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.40e-2)" "unprognostic (1.56e-1)" "unprognostic (1.85e-1)" "unprognostic (2.44e-2)" 12.6 3.1 7.0 8.7 5.8 0.7 9.7 4.5 6.9 8.7 2.9 17.6 5.6 15.4 2.0 11.0 8.5 9.4 10.8 5.8 4.5 4.9 1.2 8.5 4.4 3.7 2.7 7.1 3.8 14.7 7.9 12.6 2.8 7.7 9.8 3.4 8.6 10.2 3.5 5.3 7.7 15.4 3.4 4.0 6.7 22.0 3.5 3.1 7.4 2.4 4.8 14.2 8.3 3.5 31.9 23.2 16.2 12.9 15.4 27.8 21.3 46.4 68.1 43.6 40.0 7.4 7.2 0.1 15.2 75.5 72.3 15.1 8.6 18.7 28.6 0.9 5.7 0.0 33.2 4.5 43.0 0.0 0.4 17.2 13.8 54.4 35.5 72.2 53.0 4.8 0.7 6.8 23.0 10.3 0.6 0.0 7.0 13.2 44.3 0.0 12.1 1.5 4.7 4.1 31.8 53.0 15.9 10.9 12.4 21.4 4.1 0.3 126.7 53.0 11.8 69.6 23.0 0.0 0.2 0.0 18.9 0.1 61.9 0.0 0.4 2.9 0.4 0.1 0.5 0.0 0.6 0.6 0.0 0.0 1.2 0.5 1.0 0.0 0.0 0.0 0.5 0.7 7.0 5.8 4.5 6.9 5.8 4.5 3.7 2.7 2.8 3.4 3.5 3.5 22.5 6.4 2.0 4.6 0.2 2.9 9.7 16.2 7.4 1.2 10.2 8.9 5.9 10.0 12.7 11.0 4.2 5.6 2.3 14.8 0.0 19.2 170.5 7.5 17.6 20.1 14.5 0.0 24.7 7.7 116.3 21.1 11.2 8.8 0.0 4.4 14.3 0.0 8.5 0.0 117.2 20.6 0.0 0.3 3.6 373.8 11.1 6.0 1.8 30.9 0.6 10.2 0.0 125.2 5.4 29.9 8.6 12.4 0.6 13.5 6.4 4.2 6.4 0.7 6.6 8.0 13.4 12.5 10.0 6.2 4.3 8.8 7.3 2.6 13.9 9.9 AFTPH "FLJ20080, FLJ23793, MGC33965, Nbla10388" ENSG00000119844 Aftiphilin Q6ULP2 2 64524305-64593005 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034990, HPA034991" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Cytosol "Golgi apparatus, Vesicles" "HPA034990: AB_2674398, HPA034991: AB_10603577" "unprognostic (7.30e-2)" "unprognostic (4.72e-2)" "unprognostic (9.16e-2)" "unprognostic (8.54e-2)" "unprognostic (3.24e-1)" "unprognostic (4.25e-2)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (8.44e-2)" "unprognostic (3.42e-2)" "unprognostic (4.65e-2)" "prognostic favorable (2.37e-5)" "prognostic favorable (8.44e-4)" "unprognostic (3.12e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.83e-4)" 15.9 20.2 24.6 21.1 24.9 21.3 32.4 31.2 38.4 22.5 28.3 30.5 23.1 18.8 43.7 29.6 22.9 21.9 12.0 25.3 25.6 56.1 33.6 21.9 37.2 24.6 24.6 19.3 31.6 38.0 25.1 15.0 24.5 34.5 33.7 36.8 28.9 18.6 15.4 33.2 24.5 17.3 24.8 26.4 33.7 24.6 25.4 29.3 25.3 12.9 41.4 25.5 22.4 26.2 29.8 19.3 14.1 17.1 17.8 15.1 23.4 16.7 24.9 26.9 20.1 22.4 21.9 43.9 16.0 20.7 31.1 23.5 24.6 23.3 34.8 42.8 13.5 21.0 12.0 26.5 18.8 40.5 34.5 7.5 48.6 17.4 39.6 19.8 21.4 21.8 16.0 38.7 16.8 16.9 21.9 49.1 13.0 55.9 14.3 17.7 22.6 28.8 48.9 31.5 25.9 13.1 17.7 39.9 35.7 18.0 24.0 30.6 18.5 20.0 23.0 17.0 18.8 43.3 27.8 66.7 15.1 45.3 22.6 40.5 9.3 16.6 7.4 9.3 8.7 21.8 9.3 9.1 12.2 20.3 8.8 6.9 16.3 7.1 14.7 15.8 12.8 5.9 24.6 24.9 31.2 38.4 25.3 25.6 24.6 24.6 24.5 24.8 25.4 26.2 24.6 25.6 39.7 43.1 75.4 122.6 29.6 21.5 55.8 24.2 43.8 23.0 16.0 40.0 33.6 20.2 20.9 13.8 40.5 60.7 37.2 25.5 34.8 44.6 17.8 27.1 46.6 52.0 72.1 25.7 12.4 23.6 35.2 55.9 46.9 17.8 17.5 36.8 20.8 37.0 62.9 40.3 20.3 45.2 77.9 55.1 15.8 52.1 23.2 65.6 60.8 35.0 26.8 52.3 67.0 27.3 43.0 20.7 60.5 42.6 29.0 70.5 40.2 32.9 26.3 25.3 21.2 43.1 21.9 59.0 123.5 27.2 36.5 10.2 40.3 46.1 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 122.5" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.0;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 38.5;Proximal enterocytes: 30.5;Proximal tubular cells: 16.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HSkMC: 3.5;Karpas-707: 7.7;NTERA-2: 3.5;SCLC-21H: 3.2;TIME: 4.0;WM-115: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 2.8 0.1 0.9 0.6 2.4 0.1 1.8 0.7 1.9 0.1 0.1 1.2 9.7 0.1 14.5 0.1 0.1 3.6 0.4 0.7 1.4 8.9 122.5 0.2 0.5 1.5 1.4 0.1 0.1 0.0 0.4 0.8 1.5 0.0 0.6 0.1 0.2 0.1 0.3 0.2 14.9 0.1 0.9 0.0 0.3 3.0 1.8 0.2 0.4 0.4 0.1 1.2 0.1 4.1 0.0 2.2 0.0 1.9 0.2 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 1.2 0.0 0.7 3.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.0 1.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 15.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 2.4 0.7 1.9 0.7 1.4 1.5 1.4 1.5 0.9 1.8 4.1 10.0 0.0 0.0 6.8 0.3 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.1 11.5 0.4 3.7 0.0 0.1 0.1 0.5 0.0 0.0 1.3 0.3 0.1 1.2 1.8 2.7 1.3 0.0 0.2 1.2 0.0 0.0 0.0 0.0 1.1 83.0 0.1 0.0 1.7 0.4 0.0 1.6 0.5 1.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 33.7 38.5 0.9 0.1 0.0 0.0 0.0 30.5 16.9 0.3 0.0 6.6 0.4 2.4 1.7 6.4 0.1 0.0 0.1 0.2 0.1 0.6 0.0 AGO4 "EIF2C4, FLJ20033, hAGO4, KIAA1567" ENSG00000134698 "Argonaute RISC component 4" Q9HCK5 1 35808016-35857890 "Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 60.6;Inhibitory neurons: 72.0;Microglial cells: 63.7;Oligodendrocyte precursor cells: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "THP-1: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012179, HPA067849" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Cytoplasmic bodies" Cytosol "CAB012179: , HPA067849: " "unprognostic (2.67e-2)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (5.01e-2)" "unprognostic (1.76e-1)" "prognostic favorable (5.70e-5)" "unprognostic (3.92e-3)" "unprognostic (3.99e-3)" "unprognostic (2.32e-2)" "unprognostic (9.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-3)" "unprognostic (4.91e-3)" "unprognostic (4.96e-2)" "unprognostic (2.58e-1)" "unprognostic (3.96e-1)" "unprognostic (1.58e-2)" 8.8 4.9 7.2 8.8 7.1 20.4 7.7 8.6 7.9 8.4 8.6 9.6 4.7 8.9 6.6 7.3 7.2 6.2 9.9 6.8 6.8 5.0 7.5 11.4 7.0 7.4 7.1 7.0 8.6 6.5 5.8 8.9 7.4 8.1 6.4 18.1 8.4 6.1 13.3 20.1 7.8 9.8 6.8 14.2 9.7 7.3 7.3 7.3 5.5 11.8 6.8 8.2 8.5 7.6 6.0 1.5 11.3 6.5 5.8 6.6 5.7 4.5 4.4 4.6 5.3 0.8 9.0 9.6 6.0 6.6 4.7 2.4 4.9 3.6 4.3 10.7 4.5 4.9 4.2 2.8 5.5 5.6 7.2 4.3 7.6 2.5 3.8 8.8 7.9 11.5 3.7 3.7 6.2 0.9 9.1 6.2 3.7 3.8 2.7 9.0 10.1 1.2 4.5 7.4 5.0 7.3 4.1 3.7 12.7 9.6 3.0 24.6 9.5 3.5 1.7 3.6 3.4 5.4 1.8 1.4 4.3 7.0 3.2 1.3 2.7 3.0 0.8 1.5 1.4 0.6 0.7 1.1 2.0 0.4 0.3 0.4 7.5 0.6 1.4 0.4 0.2 0.8 7.2 7.1 8.6 7.9 6.8 6.8 7.4 7.1 7.4 6.8 7.3 7.6 16.4 19.2 21.7 54.9 6.7 9.8 4.7 5.4 9.6 28.2 8.5 7.1 21.8 12.8 9.2 11.0 22.9 4.2 17.9 5.5 1.9 5.6 2.0 12.7 9.4 11.6 12.6 5.0 60.6 5.6 4.7 7.2 10.7 10.9 2.5 11.4 22.1 11.5 13.5 6.7 72.0 8.4 2.0 42.3 10.0 1.6 5.0 28.9 3.6 63.7 33.6 6.5 6.2 87.4 54.8 14.4 11.7 5.7 4.3 9.0 10.0 1.5 10.3 32.2 19.7 6.8 8.5 11.3 1.6 5.9 12.8 4.1 10.3 3.6 5.7 6.7 AGPAT1 LPAAT-alpha ENSG00000204310 "1-acylglycerol-3-phosphate O-acyltransferase 1" Q99943 6 32168212-32178096 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 91.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 47.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048478, HPA073355" Approved Supported "Endoplasmic reticulum,Rods & Rings" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "Rods & Rings" "HPA048478: AB_2680411, HPA073355: AB_2686596" "prognostic unfavorable (1.93e-4)" "unprognostic (9.35e-3)" "unprognostic (1.87e-3)" "prognostic unfavorable (5.21e-4)" "unprognostic (4.79e-2)" "unprognostic (7.05e-2)" "unprognostic (7.16e-3)" "unprognostic (1.55e-1)" "unprognostic (3.79e-1)" "unprognostic (4.24e-3)" "unprognostic (1.84e-3)" "unprognostic (1.77e-1)" "unprognostic (6.58e-2)" "unprognostic (1.97e-2)" "unprognostic (2.16e-1)" "unprognostic (9.92e-3)" "unprognostic (7.00e-2)" 46.6 60.3 3.0 5.9 7.2 6.6 42.6 2.5 47.1 58.2 2.9 61.3 28.2 64.3 42.9 33.9 56.5 18.9 66.9 4.0 25.5 61.6 60.2 44.2 10.9 3.8 9.5 67.2 37.5 9.3 53.8 15.9 4.4 53.2 20.1 12.5 34.1 0.0 67.7 35.1 53.0 1.5 2.5 39.8 58.4 79.3 3.3 18.4 54.1 33.5 12.5 58.2 42.7 4.7 0.0 0.4 51.2 0.3 127.5 85.2 49.4 0.0 0.0 0.0 0.0 104.5 0.0 0.0 46.1 128.0 36.4 13.4 108.5 39.4 0.0 0.4 83.6 0.0 0.0 111.7 0.0 0.0 101.5 51.0 47.6 0.0 46.0 105.9 31.6 86.7 78.5 66.0 109.2 28.8 0.4 26.8 0.0 0.1 18.0 0.6 0.0 0.5 32.8 0.0 0.0 0.1 51.3 16.1 70.4 51.6 63.4 0.0 25.9 0.0 20.3 0.0 0.2 45.9 41.1 18.0 64.3 0.1 0.3 3.4 5.6 12.4 7.6 8.2 7.4 5.3 5.0 8.6 9.3 5.0 4.3 6.4 9.4 8.7 5.8 11.6 7.2 6.9 3.0 7.2 2.5 47.1 4.0 25.5 3.8 9.5 4.4 2.5 3.3 4.7 32.1 16.0 18.6 11.1 14.3 9.1 14.0 20.6 16.5 26.1 26.2 21.6 4.0 14.3 12.0 36.8 12.5 35.2 24.5 28.7 5.9 17.9 63.9 14.1 24.9 21.3 29.4 12.0 13.8 14.3 29.9 19.6 16.3 11.4 12.7 22.7 27.1 31.2 24.7 32.0 17.7 24.3 18.3 22.3 20.6 91.7 13.4 24.9 8.8 11.2 13.0 38.5 21.6 10.1 14.8 17.0 22.3 21.4 16.9 10.2 73.6 29.4 12.9 17.9 0.0 18.3 22.9 44.8 22.1 9.5 3.7 15.3 13.8 21.5 20.8 12.1 AGPAT3 "LPAAT-gamma, LPAAT3" ENSG00000160216 "1-acylglycerol-3-phosphate O-acyltransferase 3" Q9NRZ7 21 43865223-43987592 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 183.5;Early spermatids: 219.0;Late spermatids: 219.3;Rod photoreceptor cells: 184.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (2.36e-2)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.50e-2)" "unprognostic (4.56e-3)" "unprognostic (4.70e-2)" "unprognostic (8.55e-2)" "unprognostic (4.88e-2)" "unprognostic (9.72e-3)" "unprognostic (2.14e-1)" "unprognostic (3.54e-2)" "unprognostic (1.65e-1)" "unprognostic (2.84e-1)" "prognostic favorable (2.29e-4)" "unprognostic (1.50e-2)" "unprognostic (8.91e-2)" "unprognostic (1.80e-1)" "unprognostic (4.60e-2)" 20.9 20.9 41.5 19.2 47.1 11.1 15.1 42.3 34.9 11.7 14.8 22.0 44.7 10.3 12.6 25.7 12.3 13.8 27.8 38.4 36.0 53.4 53.2 18.8 16.4 52.1 41.8 10.4 21.3 24.6 14.7 12.2 39.2 13.8 11.9 61.9 30.5 11.6 62.3 24.3 52.4 8.7 47.8 19.1 18.0 26.4 48.1 15.4 21.4 50.2 10.3 15.4 15.0 48.2 73.0 40.0 10.0 27.5 17.8 20.4 7.7 32.6 40.6 40.8 25.1 40.3 51.4 24.5 24.3 39.3 38.4 27.8 17.3 36.5 11.8 117.2 45.8 10.8 24.4 54.8 33.6 39.6 23.5 25.1 30.4 36.1 15.0 35.1 31.2 8.0 61.4 39.1 15.0 31.2 0.4 22.9 4.7 28.2 28.5 40.6 11.3 65.9 29.7 70.2 34.0 24.7 40.0 45.0 29.9 3.9 31.3 42.9 46.6 25.9 0.3 39.1 34.0 31.0 50.3 15.3 33.3 78.3 23.9 0.0 3.3 2.2 1.1 7.4 1.2 0.9 1.6 1.7 3.8 1.1 1.3 1.5 0.9 0.6 9.6 0.9 3.0 1.8 41.5 47.1 42.3 34.9 38.4 36.0 52.1 41.8 39.2 47.8 48.1 48.2 17.0 12.8 25.4 33.0 7.0 8.0 9.3 14.5 7.4 40.3 19.8 12.3 33.4 25.8 21.0 25.8 183.5 15.9 10.8 45.1 9.8 25.7 219.0 17.7 16.6 16.3 13.8 12.8 34.3 29.5 1.1 10.4 19.9 18.5 5.1 24.6 15.4 68.7 19.0 65.6 37.9 19.7 12.2 32.6 27.3 219.3 7.8 25.7 1.8 17.8 38.5 34.1 9.2 19.1 28.7 26.8 18.8 5.7 11.8 18.6 60.5 52.6 31.0 184.0 6.6 14.9 24.4 7.0 2.4 17.4 11.1 12.0 14.4 22.0 22.5 15.7 AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 305.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 114.3;Basal respiratory cells: 83.8;Horizontal cells: 60.6;Ionocytes: 61.1;Pancreatic endocrine cells: 68.2;Respiratory ciliated cells: 66.8;Squamous epithelial cells: 63.7;Suprabasal keratinocytes: 164.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 135.1;HBEC3-KT: 124.9;hTCEpi: 308.7;hTERT-HME1: 130.3;TIME: 138.4" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 11.3;midbrain: 10.6;pons: 13.2;spinal cord: 38.9;thalamus: 15.0" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 40000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA000878: AB_2666127, HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: AB_2670371" "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.23e-5)" 30.4 2.3 9.8 2.4 9.9 0.0 16.4 9.3 15.9 84.5 4.6 105.3 1.4 64.3 2.9 114.1 29.2 5.1 4.5 9.7 16.0 3.5 6.2 5.1 0.1 38.1 15.3 3.5 1.6 0.7 3.4 1.8 40.8 18.6 8.6 19.0 24.0 28.6 3.6 305.9 20.2 31.6 12.4 0.9 25.2 7.7 18.1 0.4 2.8 4.5 4.7 49.4 86.6 18.5 2.9 107.6 0.1 6.0 120.0 135.1 0.2 10.5 22.3 3.8 1.9 0.3 38.9 0.1 14.5 82.9 85.3 62.9 0.3 124.9 1.7 0.0 0.4 0.0 67.5 0.5 11.0 0.0 3.8 17.6 308.7 12.1 130.3 52.3 54.7 0.0 0.0 0.2 62.8 8.0 0.0 0.0 0.3 9.5 42.9 0.3 5.7 0.1 84.4 0.0 0.6 0.6 46.2 0.1 2.3 2.8 6.0 0.0 138.4 29.3 17.9 33.8 9.9 0.0 0.0 0.0 88.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.8 9.9 9.3 15.9 9.7 16.0 38.1 15.3 40.8 12.4 18.1 18.5 3.8 12.8 1.1 0.3 0.0 114.3 4.9 83.8 13.1 8.9 2.2 1.3 1.5 0.0 38.2 1.8 2.1 0.2 0.3 0.4 0.0 11.9 24.2 16.0 10.5 13.0 0.0 0.0 8.2 8.7 0.5 31.9 0.0 18.9 17.1 0.1 3.6 2.1 1.0 60.6 5.1 0.0 61.1 0.3 12.7 3.1 0.6 0.7 32.0 3.7 0.0 3.2 0.0 1.5 3.3 68.2 0.0 0.4 0.0 4.5 0.0 0.3 66.8 13.9 0.0 13.1 8.6 0.4 4.3 63.7 164.7 0.1 0.9 0.1 0.2 6.2 AHSP "EDRF, ERAF" ENSG00000169877 "Alpha hemoglobin stabilizing protein" Q9NZD4 16 31527900-31528803 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 62 "bone marrow: 1669.9" "Cell type enriched" "Detected in some" 296 "Erythroid cells: 8721.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 3.0;K-562: 1.5" "Low region specificity" "Detected in some" HPA040940 Enhanced NA NA 5300000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 6: Erythroid cells - Oxygen transport" "HPA040940: AB_10796231" "unprognostic (3.00e-1)" "unprognostic (2.01e-1)" "unprognostic (8.44e-2)" "unprognostic (3.76e-1)" "unprognostic (1.53e-1)" "unprognostic (3.10e-1)" "unprognostic (2.16e-1)" "unprognostic (3.70e-3)" "unprognostic (2.04e-2)" "unprognostic (9.02e-2)" "unprognostic (3.25e-2)" 1.3 0.1 0.6 0.2 0.6 1669.9 0.4 0.6 2.6 0.4 0.6 0.1 0.0 0.1 0.0 0.2 0.2 0.0 1.5 0.6 0.5 1.9 4.7 4.5 0.2 0.7 0.7 0.2 0.3 0.1 1.4 27.1 0.7 0.1 0.3 0.0 0.5 0.0 0.2 1.4 0.1 0.0 0.6 23.7 0.2 4.1 0.6 2.9 0.7 8.9 0.0 0.2 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 4.7 0.6 0.6 0.6 2.6 0.6 0.5 0.7 0.7 0.7 0.6 0.6 0.8 0.1 0.0 0.0 0.0 9.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.6 0.0 8721.3 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 2.9 4.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 29.4 0.3 2.8 10.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 4.1 0.5 0.0 0.0 0.0 2.1 0.0 0.0 0.1 AJUBA "JUB, MGC15563" ENSG00000129474 "Ajuba LIM protein" Q96IF1 14 22971177-22982551 "Cancer-related genes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 61.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 47.5;Basal squamous epithelial cells: 35.3;Pancreatic endocrine cells: 33.8;Prostatic glandular cells: 34.2;Sertoli cells: 32.9;Suprabasal keratinocytes: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 217.0;hTCEpi: 222.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006171 Approved Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Golgi apparatus" "HPA006171: AB_1852044" "unprognostic (1.15e-1)" "unprognostic (2.99e-2)" "unprognostic (2.39e-1)" "unprognostic (1.24e-3)" "unprognostic (9.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-3)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.47e-1)" "unprognostic (3.19e-3)" "unprognostic (2.94e-1)" "unprognostic (2.68e-1)" "unprognostic (9.35e-3)" "unprognostic (2.07e-1)" 4.8 3.0 2.3 1.4 1.8 0.5 6.7 2.0 2.2 14.4 9.2 3.2 1.5 12.1 8.5 18.3 7.5 4.9 6.3 2.2 1.5 17.7 43.4 15.2 2.6 2.5 2.1 12.2 11.6 7.2 2.0 19.3 1.6 10.6 2.5 3.7 8.2 15.9 1.9 61.7 1.9 8.4 2.2 3.8 4.2 5.5 1.9 8.2 10.9 2.3 5.5 7.6 15.5 2.7 46.9 54.1 71.0 27.6 6.8 12.2 57.4 44.9 58.5 102.6 91.4 116.0 47.3 1.2 45.5 92.9 70.8 146.2 54.9 217.0 124.6 4.5 5.0 3.5 90.8 131.4 78.9 4.9 3.1 38.9 222.3 42.9 164.3 72.7 40.0 8.3 1.9 2.8 96.2 37.3 4.5 5.7 4.5 86.6 73.9 12.7 59.0 1.2 103.9 71.3 0.2 6.2 135.5 39.4 8.8 57.4 55.3 4.5 36.1 44.2 88.4 7.3 43.6 0.4 1.3 0.5 7.0 4.2 20.6 0.7 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.5 0.1 0.2 0.3 0.2 0.5 0.5 0.2 0.2 0.0 0.1 2.3 1.8 2.0 2.2 2.2 1.5 2.5 2.1 1.6 2.2 1.9 2.7 2.1 19.2 6.4 0.7 0.0 47.5 13.0 27.6 35.3 0.1 3.7 9.7 4.5 20.0 10.2 7.3 0.0 10.0 0.1 0.3 5.9 14.3 5.8 13.0 2.5 4.0 0.0 0.0 0.0 14.9 9.8 3.4 0.0 4.4 0.0 12.8 2.5 17.1 1.7 0.0 0.0 0.4 2.0 0.0 2.2 5.0 3.7 0.6 3.6 0.0 0.0 8.1 0.0 0.5 0.0 33.8 0.1 0.7 1.2 34.2 0.3 21.0 8.3 0.2 32.9 2.7 14.0 7.0 2.7 14.2 49.6 4.0 0.5 1.6 0.8 18.0 AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 183.5;liver: 104.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 242.6;Proximal tubular cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.1;myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Enhanced Supported Mitochondria "Intracellular and membrane" NA Yes 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" 24.7 1.9 19.5 6.6 21.0 4.9 26.6 17.8 20.8 6.1 17.5 19.7 4.3 7.0 4.2 23.4 7.6 13.7 51.7 21.4 21.2 183.5 104.0 2.8 1.6 19.0 22.8 4.6 1.2 18.3 4.7 8.3 22.8 16.2 14.0 21.9 9.6 12.7 1.7 27.4 6.6 21.4 18.5 1.2 15.0 11.3 22.7 5.7 2.5 38.8 3.3 19.1 11.8 21.1 73.2 5.0 5.6 23.9 51.6 48.7 12.0 12.1 15.0 25.6 70.8 108.1 8.6 39.1 31.0 19.0 32.1 46.1 18.8 89.9 101.9 33.0 21.5 37.9 21.9 208.6 2.5 29.9 4.6 27.2 49.6 25.1 73.0 42.2 0.9 12.2 48.0 0.6 39.6 31.2 1.1 1.3 24.6 1.0 42.5 0.2 41.0 7.1 37.8 3.2 20.5 15.4 21.6 1.5 16.7 25.8 29.7 12.9 4.2 42.4 36.2 3.3 20.9 39.5 18.8 2.1 68.7 10.9 2.5 0.9 3.1 0.0 0.1 0.6 0.2 0.2 0.1 0.2 2.7 0.1 0.1 0.1 0.4 0.3 0.1 0.4 0.0 0.8 19.5 21.0 17.8 20.8 21.4 21.2 19.0 22.8 22.8 18.5 22.7 21.1 11.2 0.0 0.5 51.2 4.7 49.7 23.6 44.2 63.7 24.5 48.9 44.7 105.7 52.9 14.3 31.3 2.1 2.2 0.6 15.8 56.7 18.6 3.4 30.1 8.2 19.6 5.4 13.9 17.1 12.1 21.1 11.4 27.5 52.2 0.0 36.4 11.7 242.6 3.3 16.8 7.7 8.7 24.4 7.8 9.2 5.8 4.1 6.9 24.9 3.7 5.7 32.7 0.0 9.5 2.5 31.9 4.3 9.4 0.4 38.7 18.8 595.5 12.3 6.5 6.6 5.6 18.8 1.8 9.5 43.1 74.3 4.9 3.6 0.7 23.1 20.4 AK7 "CFAP75, FAP75, FLJ32864" ENSG00000140057 "Adenylate kinase 7" Q96M32 14 96392128-96489427 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.3" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 97.9;Respiratory ciliated cells: 137.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "basophil: 9.0" "Lineage enriched" "Detected in single" 29 "granulocytes: 9.0" "Cell line enhanced" "Detected in many" "BEWO: 17.0;CAPAN-2: 15.1;MCF7: 49.5;REH: 35.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003543 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA003543: AB_1078117" "unprognostic (4.18e-3)" "unprognostic (1.14e-1)" "unprognostic (9.40e-3)" "prognostic favorable (3.18e-4)" "unprognostic (4.98e-5)" "unprognostic (8.41e-2)" "unprognostic (9.81e-3)" "unprognostic (1.29e-1)" "unprognostic (9.02e-2)" "unprognostic (3.65e-4)" "unprognostic (8.64e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.00e-2)" "unprognostic (1.23e-2)" "unprognostic (4.01e-2)" "unprognostic (2.25e-3)" 0.7 2.6 2.0 0.6 3.1 1.5 1.4 1.1 1.7 1.7 13.2 2.1 1.9 2.1 3.9 1.5 24.3 2.6 0.7 2.2 5.2 4.5 1.6 4.2 0.6 6.9 9.4 0.4 2.2 6.9 5.1 0.5 5.6 0.9 1.6 3.0 1.0 1.3 0.3 6.1 1.2 1.1 4.4 3.3 2.8 7.6 5.0 0.5 2.7 0.0 0.4 0.5 1.0 4.2 0.2 4.9 2.0 1.5 0.8 2.6 17.0 0.3 0.6 0.3 0.3 0.5 15.1 0.4 0.3 0.0 0.3 1.9 4.7 0.2 0.1 2.2 0.4 0.4 2.4 0.2 0.8 0.1 0.3 0.2 0.6 2.5 0.1 0.8 0.2 1.4 0.2 0.3 0.3 49.5 0.3 0.3 0.8 2.2 1.0 35.2 0.3 0.4 7.6 0.3 3.1 6.7 1.9 0.6 0.1 1.8 4.2 0.2 0.1 0.4 0.2 0.6 0.2 0.6 2.3 0.2 0.2 0.0 0.7 9.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.1 2.0 3.1 1.1 1.7 2.2 5.2 6.9 9.4 5.6 4.4 5.0 4.2 1.6 6.4 4.1 0.7 0.8 1.8 0.9 3.6 1.8 0.2 0.9 0.3 0.4 4.3 12.3 7.3 2.1 0.7 0.1 1.4 3.9 3.2 18.7 97.9 1.7 1.9 1.2 6.9 2.0 1.1 1.7 0.8 5.1 11.6 0.0 0.1 0.7 2.4 0.2 0.0 2.4 0.3 4.1 0.3 0.4 4.1 0.0 0.5 1.8 0.0 0.0 0.6 0.0 0.5 3.7 0.5 0.1 0.0 0.0 0.5 1.0 3.4 137.1 1.8 0.0 0.4 1.6 25.4 9.1 0.7 3.0 2.9 0.2 1.5 1.2 0.6 AL354761.1 ENSG00000236543 "Lipocalin 1-like" 9 135604345-135619893 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 31 "skin 1: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "BEWO: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 438.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 737.2;Oligodendrocyte precursor cells: 680.1;Oligodendrocytes: 981.1;Respiratory ciliated cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 393.4;U-138 MG: 473.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" NA NA 1600000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" 7.7 32.7 31.3 12.2 48.1 10.5 81.0 42.4 47.2 28.0 14.4 16.6 17.0 15.5 35.4 8.2 49.1 23.3 9.6 32.4 70.6 22.2 47.9 74.1 9.9 50.7 54.9 57.6 32.7 438.9 19.2 12.1 51.7 32.7 14.5 3.6 33.8 39.6 0.8 11.0 17.4 16.2 44.9 6.3 33.4 4.5 45.7 14.2 62.4 5.0 14.5 25.6 6.4 85.0 248.4 93.7 65.9 33.7 97.6 42.7 0.6 197.7 115.1 124.9 173.8 0.8 50.5 17.3 80.3 280.6 68.8 186.5 10.6 157.4 366.1 16.6 16.6 2.4 65.8 4.6 109.6 101.3 0.8 76.0 114.9 159.9 393.4 346.8 139.3 17.9 0.3 28.6 165.9 16.9 14.5 37.0 13.7 79.3 104.8 9.4 5.9 1.0 188.9 27.2 47.5 131.9 20.6 19.6 12.9 25.9 37.7 66.3 291.6 473.7 162.3 20.9 237.2 0.3 0.6 1.8 108.0 21.1 207.4 0.0 4.7 3.5 0.6 2.1 1.9 4.7 1.5 0.9 29.6 3.0 0.3 0.2 5.3 0.6 1.2 10.5 2.4 3.2 31.3 48.1 42.4 47.2 32.4 70.6 50.7 54.9 51.7 44.9 45.7 85.0 4.5 737.2 143.6 238.6 17.9 12.1 22.8 65.8 12.0 3.0 112.4 47.9 10.1 62.9 255.3 16.5 2.1 0.7 19.5 9.1 1.9 18.5 66.5 108.6 20.1 11.9 16.8 6.3 143.0 43.0 0.7 37.0 23.4 158.1 11.4 29.5 3.6 44.1 57.5 1.7 287.0 16.3 46.8 51.0 162.6 60.1 3.7 86.4 24.9 40.3 93.4 1.3 1.0 680.1 981.1 55.2 8.5 6.4 21.8 117.5 9.6 24.2 318.3 0.8 0.0 7.9 21.8 8.1 5.5 30.1 20.2 0.8 8.9 22.8 10.4 105.4 ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 172.7;smooth muscle: 128.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 85.8;Ductal cells: 64.1;Hepatocytes: 128.1;Proximal tubular cells: 165.0;Theca cells: 91.7;Undifferentiated cells: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 183.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 500000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cytosol" "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" 21.2 10.4 3.2 31.4 3.2 2.9 8.9 4.1 4.0 8.5 6.4 61.5 22.9 57.7 5.7 32.7 34.9 29.0 14.7 2.7 4.8 59.2 172.7 7.3 5.1 3.5 3.3 12.6 11.3 8.5 2.5 5.2 4.3 36.9 35.5 1.5 11.1 54.5 55.8 6.3 24.8 128.0 3.4 7.2 28.2 8.3 4.0 5.1 15.4 35.9 5.6 85.1 10.5 4.1 72.2 65.5 19.8 31.8 27.6 32.5 15.8 33.6 16.9 27.8 28.3 44.2 13.7 45.2 19.7 47.4 42.0 10.0 66.0 71.4 27.4 50.8 28.5 22.4 44.7 132.2 20.0 36.0 24.0 39.0 15.3 22.6 19.5 56.6 26.8 10.6 65.6 42.8 42.8 27.3 0.1 14.4 59.1 183.3 29.0 14.9 119.9 34.5 25.1 31.7 43.3 19.9 25.7 16.7 19.4 20.6 15.9 27.9 18.2 31.9 52.4 26.9 42.5 6.5 13.2 17.8 16.4 36.0 22.1 0.3 4.2 0.2 6.7 9.2 9.6 5.5 6.5 6.1 9.5 2.6 5.1 6.2 1.0 8.0 11.9 1.2 5.0 5.3 3.2 3.2 4.1 4.0 2.7 4.8 3.5 3.3 4.3 3.4 4.0 4.1 3.3 9.6 1.7 0.0 3.7 1.0 5.7 9.4 2.2 1.2 3.7 4.2 6.6 85.8 3.8 16.5 2.1 2.0 1.2 12.8 17.6 64.1 0.6 2.3 6.4 4.7 15.6 12.8 0.5 6.9 46.6 6.6 8.2 3.4 8.9 12.8 8.9 128.1 7.2 0.0 1.1 25.5 6.1 4.1 2.4 2.2 6.5 4.2 0.0 0.0 5.5 2.1 0.0 0.5 0.5 15.0 7.7 6.8 3.7 6.1 10.3 165.0 0.3 0.7 0.0 6.0 16.1 0.6 0.8 2.1 1.0 1.8 3.3 91.7 71.7 2.8 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 389.5;Basal squamous epithelial cells: 274.3;Club cells: 150.1;Gastric mucus-secreting cells: 437.9;Respiratory ciliated cells: 412.7;Squamous epithelial cells: 342.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "A549: 5094.7;OE19: 6071.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 1.7 1.0 0.4 1.3 0.7 0.1 3.2 0.3 0.4 6.7 17.5 4.5 6.2 0.3 0.2 496.1 5.5 10.3 0.3 1.0 0.4 1.3 1.9 10.9 0.5 0.6 2.1 0.4 0.5 0.0 0.9 0.0 0.5 1.9 3.3 0.1 128.0 1.5 1.3 72.6 3.5 0.4 0.9 0.9 224.8 1.6 1.3 0.6 0.5 0.3 33.7 6.2 22.3 0.9 0.1 5094.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 10.7 246.5 0.0 2.7 0.5 2.0 29.3 0.7 12.8 0.0 0.0 0.8 0.1 116.6 1.0 0.3 0.1 0.5 0.0 14.9 0.5 0.4 0.2 0.5 0.0 0.0 0.0 0.0 9.7 0.1 0.3 0.4 6071.6 19.8 0.0 0.0 0.0 0.0 87.0 0.2 0.6 24.8 0.0 0.0 0.2 0.2 0.9 0.6 0.3 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.4 1.0 0.4 0.6 2.1 0.5 0.9 1.3 0.9 0.7 3.2 5.5 0.0 0.7 44.1 46.8 389.5 274.3 0.0 0.1 1.5 0.4 2.8 150.1 0.0 0.0 0.0 0.0 5.1 0.0 1.4 1.5 12.4 0.2 1.3 1.8 0.0 0.1 0.5 0.0 1.6 437.9 0.8 2.5 0.3 1.4 3.2 0.2 0.0 0.0 4.8 83.4 0.3 1.8 5.2 0.9 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 9.5 4.7 1.9 3.2 5.8 3.4 5.0 412.7 0.2 0.0 1.7 20.1 1.7 8.6 342.2 32.0 0.0 0.5 0.2 8.4 64.3 ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 288.6" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 287.4;Squamous epithelial cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 285.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" 75.2 203.0 23.1 15.2 32.5 9.3 34.9 24.8 27.7 49.4 71.7 49.6 68.1 29.4 41.7 131.3 38.3 70.5 44.6 29.0 27.9 173.0 288.6 59.1 14.9 23.3 26.3 32.3 52.3 40.6 21.9 11.8 23.5 75.0 36.5 40.8 61.7 41.5 53.0 207.6 71.8 30.2 25.1 19.4 81.5 26.9 24.8 23.0 75.1 100.9 36.4 24.2 40.5 33.6 27.7 147.0 29.2 58.5 88.7 89.4 19.1 12.3 29.9 24.4 27.6 63.2 52.5 12.3 35.9 50.5 29.3 99.0 59.8 125.2 19.9 36.2 42.5 5.3 120.9 142.8 12.2 30.6 5.4 42.9 137.6 22.9 12.2 49.7 49.2 25.5 2.2 0.6 37.3 45.3 0.7 25.2 32.3 285.4 78.5 38.6 64.1 25.3 17.5 132.3 46.3 30.4 98.9 38.4 35.3 152.2 78.1 35.0 46.7 10.1 28.7 68.8 45.6 11.3 28.6 15.5 47.4 0.3 48.3 0.8 21.1 17.5 6.3 18.3 9.9 5.2 6.0 6.1 20.7 4.9 6.8 6.3 2.2 15.0 20.6 1.3 11.3 11.0 23.1 32.5 24.8 27.7 29.0 27.9 23.3 26.3 23.5 25.1 24.8 33.6 22.1 176.3 86.5 14.7 13.3 57.1 143.9 85.1 287.4 15.3 13.6 24.0 54.1 105.8 86.5 33.1 12.5 12.5 8.2 48.9 43.0 97.5 79.6 47.5 13.4 19.5 16.2 8.2 30.5 52.0 4.6 39.9 87.7 36.9 29.7 34.6 13.6 116.7 24.6 6.7 20.1 27.7 26.4 21.7 15.1 19.5 55.9 23.5 7.2 13.1 25.7 105.9 8.2 19.6 29.1 43.9 28.7 80.5 28.6 104.2 90.6 119.2 59.2 21.4 13.1 70.1 22.1 15.5 24.0 232.6 90.2 1.4 13.2 29.1 46.0 51.4 ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 162.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 414.1;Proximal tubular cells: 302.1;Syncytiotrophoblasts: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 256.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 430000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" 23.7 38.3 46.6 9.1 47.6 1.8 47.1 43.7 45.8 32.7 40.7 29.5 23.7 25.1 8.8 35.9 28.8 19.1 27.9 44.7 43.2 115.1 162.2 15.7 8.6 43.1 43.5 65.3 27.0 34.0 8.8 44.9 42.6 42.0 27.4 19.7 40.6 27.9 12.2 29.4 21.0 23.6 44.8 7.0 23.6 12.3 44.0 18.3 47.6 26.5 17.1 18.1 20.9 45.2 64.9 41.9 116.6 193.4 95.5 56.4 147.8 76.1 93.4 86.5 110.5 118.6 60.7 0.0 75.5 60.0 36.1 47.1 36.5 256.2 78.8 0.1 44.6 12.3 63.1 102.1 46.3 0.2 0.0 69.0 59.2 67.3 47.7 64.2 70.0 0.0 0.0 0.1 77.1 42.1 2.6 0.3 79.4 47.5 35.2 38.9 131.8 0.0 81.2 48.4 39.4 47.2 0.0 41.1 44.7 89.0 75.2 2.7 86.1 24.8 75.6 28.8 53.1 0.1 0.1 0.4 13.4 0.2 40.6 0.7 0.2 0.1 0.1 0.0 0.2 0.8 0.2 0.1 1.8 0.6 1.2 0.6 0.1 0.1 0.0 6.4 0.0 0.4 46.6 47.6 43.7 45.8 44.7 43.2 43.1 43.5 42.6 44.8 44.0 45.2 17.6 16.0 29.3 99.3 5.0 25.9 59.5 110.0 87.0 23.6 40.6 91.1 39.9 27.1 43.5 42.3 22.9 414.1 3.7 15.2 76.3 43.5 31.4 18.7 44.3 19.1 21.7 5.2 16.0 13.8 107.8 34.0 27.0 21.4 7.0 50.4 18.9 74.6 51.1 25.2 21.5 25.9 20.3 9.4 7.6 41.7 25.4 9.1 55.2 12.2 7.5 102.1 0.0 41.7 30.0 12.6 15.6 37.2 2.0 27.5 23.4 302.1 23.4 13.6 19.7 19.4 25.8 1.0 5.1 59.2 16.1 222.3 4.6 39.3 46.4 50.4 ALG1L ALG1L1 ENSG00000189366 "ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like" Q6GMV1 3 125929275-125937039 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 10.8;urinary bladder: 9.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 33.6;Club cells: 15.2;Endometrial ciliated cells: 10.5;Ionocytes: 12.2;Respiratory ciliated cells: 46.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 15.9;CAPAN-2: 14.3;HaCaT: 15.2;MCF7: 30.1;OE19: 19.1;T-47d: 19.7" HPA036108 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA036108: AB_10673344" "unprognostic (7.06e-3)" "unprognostic (1.50e-3)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "prognostic favorable (3.00e-4)" "unprognostic (2.40e-2)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (2.10e-1)" "unprognostic (1.47e-1)" "unprognostic (4.37e-2)" "unprognostic (5.79e-2)" "unprognostic (4.50e-6)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "unprognostic (1.57e-2)" "prognostic favorable (6.24e-4)" 0.5 1.1 2.5 1.1 2.7 0.3 1.4 2.0 3.0 1.6 1.4 1.4 0.4 1.4 10.8 1.6 2.2 0.8 0.7 2.4 2.6 1.7 1.4 1.0 0.4 2.5 2.4 2.3 1.3 0.6 1.8 1.5 2.5 1.8 0.8 0.6 1.9 0.9 6.7 5.8 0.5 0.5 2.1 0.3 1.5 1.2 2.4 1.1 1.6 2.6 2.7 9.4 1.5 2.5 1.1 0.8 0.4 0.0 0.0 0.2 1.8 0.1 0.0 0.2 0.4 15.9 14.3 4.4 6.8 0.0 0.3 15.2 0.4 0.0 0.8 0.6 3.6 0.8 2.4 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.0 4.1 1.2 1.4 0.0 30.1 1.0 0.3 6.4 19.1 3.8 0.1 0.1 7.4 0.0 0.9 2.4 0.9 0.5 0.2 0.7 3.2 19.7 0.4 0.3 0.2 2.2 0.2 0.1 10.9 1.7 5.9 0.2 0.0 1.0 2.5 0.0 0.1 2.0 0.1 1.1 1.6 1.0 2.2 0.0 0.9 1.2 0.7 0.4 3.2 0.0 1.3 2.7 0.9 2.5 2.7 2.0 3.0 2.4 2.6 2.5 2.4 2.5 2.1 2.4 2.5 0.2 0.0 0.5 0.3 0.7 3.3 1.7 33.6 0.6 0.3 2.1 2.4 0.0 0.0 15.2 1.8 0.0 3.5 0.5 0.3 1.9 0.4 1.7 10.5 0.8 0.3 1.8 0.0 1.2 0.4 2.0 1.1 0.0 0.4 1.3 1.4 0.0 0.1 0.3 0.0 1.7 0.2 12.2 0.0 1.2 1.8 1.8 0.1 1.8 0.0 0.2 1.5 2.1 1.0 0.6 0.6 1.4 3.0 0.4 0.5 0.0 1.0 46.0 0.0 0.0 2.7 2.6 1.4 1.6 0.3 5.1 1.4 0.5 2.4 0.4 8.2 ALOX12B 12R-LOX ENSG00000179477 "Arachidonate 12-lipoxygenase, 12R type" O75342 17 8072636-8087716 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 90.2" "Cell type enhanced" "Detected in some" "Horizontal cells: 1.7;Rod photoreceptor cells: 1.2;Spermatogonia: 1.2;Suprabasal keratinocytes: 1.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 4.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.3" "Cell line enhanced" "Detected in some" "A549: 1.1;HEK 293: 1.3;hTCEpi: 1.6;JURKAT: 2.7;OE19: 1.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024002 Supported Supported Vesicles,Cytosol NA NA 7000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Cytosol Vesicles "HPA024002: AB_1844757" "unprognostic (1.27e-2)" "unprognostic (1.59e-2)" "unprognostic (4.28e-3)" "unprognostic (1.38e-2)" "unprognostic (3.94e-3)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.04e-1)" "unprognostic (4.40e-2)" "unprognostic (9.55e-2)" "unprognostic (6.66e-3)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (8.01e-2)" "unprognostic (3.46e-2)" 0.0 0.0 0.4 0.1 0.5 0.1 2.1 0.4 0.6 5.7 0.0 0.1 0.3 0.0 0.0 5.6 0.2 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.5 0.4 0.2 0.0 0.2 1.2 0.1 0.0 0.5 0.4 0.1 0.6 0.8 0.0 0.4 90.2 0.2 0.0 0.1 0.2 0.2 0.2 0.4 0.6 0.0 0.0 19.1 0.0 15.0 0.1 0.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.3 0.0 0.0 0.0 1.3 0.0 0.4 0.1 0.0 0.2 0.0 0.0 1.6 0.1 0.5 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.8 0.0 0.9 0.0 0.4 0.4 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.2 0.0 0.4 0.6 0.1 0.2 0.0 0.1 0.5 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.5 0.4 0.6 0.4 0.2 0.4 0.2 0.5 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.5 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.8 1.2 0.0 1.8 0.0 0.0 0.0 0.1 0.1 ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase type B" O15296 17 8039034-8049134 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 111.7;prostate: 73.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 75.8;Basal respiratory cells: 22.0;Kupffer cells: 42.2;monocytes: 87.9;Prostatic glandular cells: 25.6;Squamous epithelial cells: 44.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 91.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "classical monocyte: 3.9;myeloid DC: 4.3" "Group enriched" "Detected in many" 8 "dendritic cells: 4.3;monocytes: 3.9" "Cell line enhanced" "Detected in some" "HHSteC: 7.7;HSkMC: 16.6;hTCEpi: 35.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Cytosol" "HPA010562: AB_2668305" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (2.56e-1)" "unprognostic (2.28e-3)" "unprognostic (1.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.59e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.49e-2)" 2.2 1.7 0.7 1.3 0.7 0.4 111.7 0.6 2.5 12.0 0.5 2.3 0.1 1.1 0.9 39.1 1.6 0.7 0.7 0.7 0.8 0.5 0.4 24.5 2.9 1.8 0.9 0.7 1.4 0.2 0.5 1.2 1.6 73.1 0.3 0.3 3.7 0.1 0.3 36.9 3.7 0.1 0.9 3.8 4.4 0.5 0.9 0.7 1.9 0.1 7.6 1.7 33.4 1.9 0.1 0.0 0.0 0.1 0.5 0.7 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 16.6 35.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.9 0.7 0.7 0.6 2.5 0.7 0.8 1.8 0.9 1.6 0.9 0.9 1.9 1.4 0.0 75.8 0.0 0.3 3.1 0.6 22.0 7.4 0.0 19.8 12.3 0.3 1.5 8.2 0.0 0.0 0.2 0.2 0.2 0.0 0.1 1.3 0.0 0.8 0.4 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.2 1.3 0.0 0.7 0.3 4.2 0.0 0.0 0.0 2.0 42.2 1.1 0.8 0.0 15.4 5.4 0.0 87.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 25.6 0.0 0.0 2.2 0.0 0.0 0.1 1.3 0.6 0.8 44.4 1.1 0.8 0.0 0.0 0.0 2.2 ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "skin 1: 56.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.1;Pancreatic endocrine cells: 6.3;Prostatic glandular cells: 1.8;Spermatocytes: 1.8;Spermatogonia: 1.7;Suprabasal keratinocytes: 1.8" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 3.9;melanoma: 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 6.4;HBEC3-KT: 10.1;hTCEpi: 7.3;hTERT-HME1: 13.7;T-47d: 4.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: AB_2732385" "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" 0.0 0.0 0.5 0.0 0.3 0.0 1.6 1.9 2.1 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.4 0.2 0.1 0.7 0.1 0.0 0.1 0.3 0.0 0.1 56.2 0.0 0.0 0.1 0.0 0.0 0.8 1.0 0.0 0.0 0.0 1.2 0.0 1.8 0.5 6.4 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.4 0.1 0.5 0.2 0.2 0.1 2.9 0.4 0.8 10.1 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.3 0.1 13.7 0.0 0.0 0.9 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.7 0.0 0.0 4.4 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 1.9 2.1 0.7 0.4 0.8 0.7 0.7 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 2.1 1.2 0.0 0.0 0.6 0.5 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.4 0.1 0.1 0.2 0.0 0.0 1.2 0.9 1.2 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 1.7 0.3 1.8 1.1 0.0 0.0 0.0 0.6 AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 134.3;liver: 180.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.7;Hepatocytes: 21.6;Late spermatids: 21.6;Proximal tubular cells: 38.5" "Group enriched" "Detected in all" 4 "liver cancer: 8.8;prostate cancer: 34.5;renal cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 175.4;U-266/84: 98.0" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 70000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" 8.6 15.0 5.9 5.0 5.5 3.0 6.4 4.6 6.0 6.5 4.6 40.0 18.0 4.7 9.6 15.6 6.2 20.5 10.1 5.4 7.8 134.3 180.6 9.2 3.6 5.9 6.4 7.8 13.8 13.0 5.7 7.7 6.6 39.3 42.9 12.0 60.7 12.5 19.2 4.9 15.9 7.0 5.8 5.4 34.8 4.3 8.4 4.8 8.3 14.9 5.6 8.8 8.5 5.8 12.7 20.2 11.1 14.3 7.7 11.9 19.1 16.6 12.2 7.6 5.7 66.1 15.1 4.1 8.7 23.6 28.6 5.8 2.8 12.0 7.7 12.7 10.9 9.8 13.7 19.0 5.4 6.0 3.0 18.1 6.0 9.7 3.6 10.7 8.5 8.3 3.8 14.7 22.4 9.6 5.0 7.6 10.0 9.4 32.9 6.0 18.6 6.5 33.2 62.4 6.1 8.7 27.6 19.3 16.9 9.1 14.9 5.9 15.6 24.6 5.4 6.2 13.6 175.4 98.0 7.4 7.0 12.1 18.8 0.3 6.0 9.3 8.3 8.0 7.0 7.1 7.2 6.4 8.9 5.2 6.6 4.8 10.0 8.7 14.2 4.6 7.9 6.0 5.9 5.5 4.6 6.0 5.4 7.8 5.9 6.4 6.6 5.8 8.4 5.8 0.8 3.2 4.1 0.0 2.2 0.4 0.4 0.9 1.8 4.3 1.4 0.9 1.1 8.6 3.7 1.8 0.0 1.0 2.2 19.7 5.9 0.8 8.9 2.3 1.2 3.0 4.2 2.1 0.0 3.8 1.0 2.9 4.1 1.5 0.0 1.2 1.1 21.6 1.1 5.0 0.0 5.1 4.1 0.9 0.2 21.6 0.6 1.2 0.0 0.0 1.5 9.3 3.1 0.0 0.0 2.6 4.5 2.2 1.6 0.6 4.7 38.5 3.1 0.9 0.0 1.7 3.7 0.7 0.7 3.4 0.6 0.3 1.5 1.2 4.4 0.4 AMBRA1 "DCAF3, FLJ20294, KIAA1736, WDR94" ENSG00000110497 "Autophagy and beclin 1 regulator 1" Q9C0C7 11 46396414-46594125 "Predicted intracellular proteins" "Autophagy, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 65.6;Excitatory neurons: 101.4;Inhibitory neurons: 101.9;Microglial cells: 84.3;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 11.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017825, HPA038535" Approved Approved Vesicles,Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Mitochondria "CAB017825: , HPA038535: AB_2676068" "unprognostic (1.76e-3)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (1.56e-1)" "unprognostic (6.00e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-3)" "unprognostic (7.78e-2)" "unprognostic (1.32e-1)" "unprognostic (1.98e-2)" "unprognostic (5.53e-3)" "unprognostic (2.32e-1)" "prognostic favorable (1.61e-4)" "unprognostic (2.90e-1)" "unprognostic (8.17e-2)" "unprognostic (1.61e-2)" "unprognostic (7.98e-2)" 10.2 16.4 7.5 6.7 9.1 11.6 10.5 7.8 9.1 10.4 7.4 10.1 10.0 11.7 5.8 10.6 10.1 6.4 8.4 7.9 6.4 8.2 9.1 8.6 8.2 6.6 6.1 11.6 8.3 12.3 9.2 7.6 7.3 9.8 7.0 7.8 10.6 7.6 13.0 17.4 9.8 8.8 5.4 10.3 9.7 12.6 8.4 13.5 9.4 8.3 8.1 9.4 10.0 10.8 8.7 23.0 15.5 16.8 16.1 12.0 9.6 8.5 16.1 13.6 14.1 17.4 14.8 17.5 8.5 15.1 16.1 15.4 7.9 15.0 10.0 15.3 25.5 11.9 14.6 22.5 10.5 17.3 14.6 16.7 11.6 8.6 16.3 14.8 14.3 14.9 20.8 11.7 10.2 21.4 22.2 12.2 26.1 19.6 12.4 21.5 21.3 9.7 13.1 15.4 12.5 13.9 14.7 16.6 15.6 10.1 17.2 11.6 15.2 12.5 11.1 14.6 12.8 13.2 11.3 18.1 11.1 9.6 11.3 11.8 2.2 1.7 2.6 1.1 2.2 2.4 1.9 2.0 2.0 2.1 1.9 1.7 2.5 1.4 1.9 2.1 3.2 1.9 7.5 9.1 7.8 9.1 7.9 6.4 6.6 6.1 7.3 5.4 8.4 10.8 5.1 3.2 5.6 65.6 7.2 4.1 2.5 3.4 4.0 6.6 5.1 5.2 8.2 4.3 4.3 0.0 2.1 4.0 5.9 16.0 0.0 6.9 13.8 5.2 5.3 4.7 9.6 10.3 101.4 9.3 2.1 6.7 13.7 8.3 4.5 8.8 3.6 4.1 5.2 5.0 101.9 9.7 2.0 3.5 2.3 6.7 5.3 4.8 5.4 84.3 3.1 3.2 6.2 84.9 136.4 8.4 7.5 7.9 6.6 3.5 8.2 3.2 4.4 5.7 13.1 4.2 5.8 2.1 2.1 7.4 4.5 6.8 6.4 7.9 6.4 4.2 AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 41.5;ovary: 33.1" "Group enriched" "Detected in some" 4 "granulocytes: 26.0;Granulosa cells: 36.1;Theca cells: 94.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "HEL: 40.1;K-562: 22.2" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 11 "hippocampal formation: 9.4" "HPA060228, HPA069636" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Cytosol" "HPA060228: AB_2684227, HPA069636: AB_2686163" "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" 0.6 41.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.1 0.5 0.0 0.3 0.0 0.9 0.4 0.0 0.0 0.2 33.1 12.5 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 4.2 0.1 0.1 0.0 0.0 5.7 0.7 9.1 0.5 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 40.1 0.0 0.8 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 22.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 3.5 2.6 0.0 0.1 1.5 0.0 4.2 0.1 2.1 0.1 2.7 0.0 0.1 26.0 36.1 11.4 0.3 0.1 0.0 0.0 0.0 0.0 1.2 0.0 2.5 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.1 0.3 0.0 0.0 0.3 0.8 94.9 0.1 0.0 AMMECR1 ENSG00000101935 "AMMECR nuclear protein 1" Q9Y4X0 X 110194186-110440318 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Alport syndrome, Deafness, Disease variant, Elliptocytosis, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 83.1;Excitatory neurons: 92.8;Inhibitory neurons: 108.7;Rod photoreceptor cells: 87.3;Syncytiotrophoblasts: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000590, HPA051762" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Mitochondria "HPA000590: AB_2666037, HPA051762: AB_2681596" "unprognostic (7.77e-2)" "unprognostic (1.93e-1)" "unprognostic (2.06e-1)" "unprognostic (5.17e-2)" "unprognostic (1.25e-1)" "unprognostic (6.87e-2)" "unprognostic (1.66e-3)" "unprognostic (6.55e-2)" "unprognostic (5.98e-2)" "prognostic favorable (6.62e-5)" "unprognostic (3.61e-2)" "unprognostic (3.96e-2)" "unprognostic (2.43e-3)" "unprognostic (3.33e-1)" "unprognostic (1.02e-1)" "prognostic favorable (8.44e-4)" "unprognostic (7.82e-2)" 3.6 2.9 1.7 3.7 1.7 13.4 3.4 1.8 2.0 2.9 8.5 3.7 3.1 2.3 2.1 7.9 3.3 2.3 1.1 1.5 1.7 3.4 3.3 2.8 4.2 1.3 1.3 5.5 2.0 2.2 2.0 7.0 1.2 2.2 3.9 14.5 2.8 1.9 1.3 7.4 3.3 2.9 1.0 3.7 3.7 1.6 1.7 4.5 2.4 1.7 5.7 4.8 4.5 1.5 20.3 9.8 7.1 3.4 7.9 11.8 7.8 13.8 12.3 11.1 16.2 15.9 14.4 12.0 6.4 18.4 9.0 9.5 22.7 15.7 11.3 8.4 10.1 16.7 21.7 3.3 19.9 13.5 6.7 6.6 27.3 12.7 22.6 6.0 8.9 5.9 47.1 34.8 8.5 17.2 6.5 4.8 32.6 17.4 19.1 13.7 7.6 21.2 18.8 16.8 11.3 5.3 23.2 22.7 19.9 8.5 5.6 13.3 4.1 7.6 4.6 22.8 12.6 7.1 8.6 18.9 11.6 27.5 25.9 0.6 0.9 0.8 1.6 0.6 2.1 1.6 3.2 2.6 1.5 2.2 2.1 1.9 0.4 0.6 2.7 0.6 2.3 1.0 1.7 1.7 1.8 2.0 1.5 1.7 1.3 1.3 1.2 1.0 1.7 1.5 4.4 0.0 9.8 17.9 11.5 9.6 3.9 10.5 5.7 35.3 7.5 4.4 4.2 8.6 8.9 3.7 52.1 27.2 9.5 8.9 23.5 9.2 0.5 10.5 7.7 9.6 15.0 83.1 92.8 12.0 9.9 12.8 13.7 13.4 2.5 14.4 19.6 8.4 7.1 1.7 108.7 11.2 12.2 7.6 3.1 2.1 12.8 7.3 3.6 21.5 9.4 7.1 14.4 35.7 19.2 11.5 3.7 17.3 8.0 9.1 10.3 10.2 10.4 87.3 13.1 6.7 8.4 2.2 6.9 17.4 26.7 86.5 13.0 34.7 10.5 15.7 AMPD3 ENSG00000133805 "Adenosine monophosphate deaminase 3" Q01432 11 10308313-10507579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 62.9;skeletal muscle: 73.3" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 44.2;CAPAN-2: 34.6;HMC-1: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038662, HPA047408" Uncertain Approved "Nuclear membrane" NA NA 77000 "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear membrane" "HPA038662: AB_2676136, HPA047408: AB_2680034" "unprognostic (2.24e-1)" "unprognostic (3.88e-3)" "unprognostic (1.44e-2)" "prognostic favorable (2.37e-4)" "unprognostic (1.89e-2)" "unprognostic (1.71e-3)" "unprognostic (2.91e-3)" "unprognostic (1.25e-1)" "unprognostic (7.83e-2)" "unprognostic (2.26e-1)" "unprognostic (1.84e-2)" "unprognostic (4.68e-1)" "unprognostic (3.06e-2)" "unprognostic (7.07e-2)" "unprognostic (4.42e-2)" "unprognostic (2.98e-1)" "unprognostic (2.12e-2)" 4.2 19.6 10.8 20.7 22.5 62.9 3.0 19.1 15.3 6.0 10.8 4.9 6.5 4.2 4.0 7.6 11.1 6.4 2.9 10.4 15.9 7.8 1.8 6.9 17.6 21.1 20.5 2.6 3.3 24.1 18.2 4.1 20.5 7.4 6.6 7.5 6.4 3.5 73.3 15.6 7.8 4.4 14.0 12.1 6.7 1.8 21.4 13.9 3.6 9.3 20.3 9.7 7.9 30.2 14.1 2.0 0.5 0.2 7.1 5.0 0.8 12.4 44.2 3.0 3.1 6.9 34.6 5.1 1.2 5.7 11.9 8.6 0.2 11.8 8.8 12.7 0.5 12.5 1.8 1.0 2.4 17.2 36.0 18.5 17.9 6.0 7.7 7.5 1.4 8.3 19.4 5.3 10.1 0.5 10.2 22.3 1.6 1.1 12.2 3.7 15.9 18.2 0.6 11.5 5.1 2.6 2.7 0.4 0.8 1.0 0.4 5.8 3.4 13.7 0.2 9.6 0.5 4.8 2.9 5.5 15.7 16.9 0.3 9.5 6.4 19.4 2.2 3.9 5.4 7.7 3.3 2.6 4.2 5.3 3.6 2.5 8.4 3.8 1.7 2.7 2.1 2.8 10.8 22.5 19.1 15.3 10.4 15.9 21.1 20.5 20.5 14.0 21.4 30.2 0.5 0.0 3.9 5.2 14.3 12.5 10.6 8.1 4.0 23.6 1.6 1.8 6.3 5.7 9.8 14.7 2.1 0.9 1.6 1.9 17.6 2.9 7.3 14.0 1.7 1.6 10.2 20.2 11.9 1.6 1.5 8.1 3.1 2.9 12.0 0.9 1.1 0.7 14.5 0.0 7.0 3.9 20.3 15.2 7.6 20.6 0.9 18.3 3.6 28.1 14.0 6.5 1.0 5.0 111.8 6.3 3.0 0.0 1.7 26.5 4.9 0.8 24.2 1.3 0.0 12.3 1.9 0.4 0.6 2.2 12.5 1.2 6.6 0.3 2.2 16.8 ANGEL1 "Ccr4e, KIAA0759" ENSG00000013523 "Angel homolog 1" Q9UNK9 14 76786009-76826246 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Late spermatids: 75.1;Oligodendrocyte precursor cells: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000948 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA000948: AB_2227189" "unprognostic (4.81e-2)" "unprognostic (2.37e-2)" "unprognostic (2.67e-1)" "unprognostic (2.46e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-1)" "unprognostic (7.33e-2)" "prognostic favorable (3.43e-4)" "unprognostic (9.24e-2)" "unprognostic (1.01e-1)" "prognostic favorable (5.46e-4)" "unprognostic (3.03e-1)" "unprognostic (6.92e-3)" "unprognostic (1.42e-1)" "unprognostic (2.22e-1)" "unprognostic (1.53e-1)" "unprognostic (6.32e-2)" 11.3 18.5 18.3 11.8 19.7 6.8 12.7 16.7 21.2 12.8 15.6 10.0 9.2 14.8 23.8 7.0 12.2 11.4 15.7 19.2 21.1 11.6 19.3 14.0 12.2 22.5 19.6 19.3 50.8 17.2 21.1 10.4 21.5 9.3 10.9 26.4 15.8 8.4 12.2 6.4 10.3 12.3 18.1 29.3 15.8 52.4 20.1 8.1 13.7 9.8 10.9 9.5 8.5 23.8 13.1 14.0 15.2 13.6 12.2 11.1 14.1 7.7 11.0 7.8 9.9 13.5 18.2 23.8 11.1 6.7 10.6 16.2 14.6 13.7 13.1 10.1 13.1 14.8 9.7 10.3 7.9 7.8 8.7 11.8 16.8 7.3 14.5 11.3 20.0 24.8 14.5 6.2 8.2 25.3 14.0 11.6 17.5 20.7 18.4 17.0 10.4 14.1 11.8 18.4 21.5 9.6 11.6 15.8 7.1 13.8 31.1 8.4 9.6 9.1 8.0 6.9 6.4 15.9 12.9 14.7 7.7 13.7 11.8 0.8 4.8 1.6 5.9 5.5 7.2 6.8 5.3 5.6 7.5 5.5 7.5 5.6 1.4 5.5 7.1 4.9 4.5 5.9 18.3 19.7 16.7 21.2 19.2 21.1 22.5 19.6 21.5 18.1 20.1 23.8 7.4 6.4 10.5 17.6 4.7 1.1 1.8 1.5 2.2 2.4 5.7 5.0 6.7 5.7 2.2 3.7 10.4 1.5 1.5 2.1 0.0 3.3 64.3 3.7 3.9 10.0 4.2 4.2 18.3 3.2 2.8 4.3 1.5 3.3 1.3 15.9 7.1 9.5 7.2 0.0 19.7 4.4 4.1 5.7 2.0 75.1 2.1 5.5 1.8 23.4 1.4 4.9 1.0 64.8 30.2 2.5 1.0 4.9 8.9 3.4 1.7 1.3 1.4 8.9 6.6 5.1 2.4 15.9 4.9 2.8 0.4 1.2 3.0 12.9 4.6 1.5 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 ANGPTL1 "ANG3, ANGPT3, AngY, ARP1" ENSG00000116194 "Angiopoietin like 1" O95841 1 178849535-178871077 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 133.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 81.7;Leydig cells: 425.9;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "ASC diff: 149.9;ASC TERT1: 60.1;HHSteC: 64.9;HSkMC: 147.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009976 Approved "Secreted to blood" NA NA 380000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009976: AB_1844822" "unprognostic (2.59e-2)" "unprognostic (1.31e-1)" "unprognostic (5.80e-3)" "unprognostic (2.63e-2)" "unprognostic (3.60e-1)" "unprognostic (1.71e-2)" "prognostic favorable (8.73e-4)" "unprognostic (3.81e-2)" "unprognostic (5.78e-3)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (5.31e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.49e-2)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.61e-3)" 56.6 45.1 2.0 10.5 2.7 0.9 26.9 2.3 2.7 21.3 1.5 56.7 9.6 69.2 14.0 33.8 59.0 27.9 22.8 2.9 1.9 17.5 23.9 12.6 3.5 2.1 1.5 68.2 21.9 1.1 2.1 133.8 1.4 12.3 27.5 9.6 36.3 9.5 30.3 9.0 26.7 65.5 2.2 10.9 21.6 15.6 1.7 8.6 41.1 57.3 6.9 23.9 17.1 2.3 0.2 0.0 4.0 0.0 149.9 60.1 0.0 0.1 0.0 0.4 0.8 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 64.9 0.0 0.1 147.5 0.0 2.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.9 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.1 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 2.7 2.3 2.7 2.9 1.9 2.1 1.5 1.4 2.2 1.7 2.3 16.5 0.0 0.0 9.4 1.3 3.7 0.0 0.0 1.2 2.3 0.8 0.5 3.7 41.5 0.0 1.8 6.2 0.6 0.1 0.0 1.9 2.4 1.4 3.3 40.3 4.1 0.0 0.0 14.8 0.4 0.4 81.7 1.1 5.5 0.0 1.6 8.9 1.0 1.4 0.0 14.9 0.0 0.0 0.0 4.6 10.6 425.9 0.8 3.6 8.4 0.0 31.6 0.0 21.6 0.7 0.0 5.0 212.1 0.4 0.1 0.1 0.1 0.7 10.9 39.5 10.0 51.8 0.8 0.6 0.2 3.7 1.4 0.5 2.7 0.0 0.1 ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Group enriched" "Detected in many" 4 "Astrocytes: 1101.2;Bipolar cells: 376.6;Cone photoreceptor cells: 479.6;Excitatory neurons: 1282.0;Horizontal cells: 1431.8;Inhibitory neurons: 1060.7;Oligodendrocyte precursor cells: 497.1;Oligodendrocytes: 1351.0;Rod photoreceptor cells: 484.4" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 29.2;ASC TERT1: 32.2;RH-30: 49.6;SH-SY5Y: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" 31.0 13.6 94.9 11.2 109.0 0.1 18.3 63.1 165.7 31.6 0.0 30.1 8.5 15.8 5.9 12.9 9.6 22.5 119.5 103.9 77.5 110.1 2.4 7.2 9.2 130.2 61.1 27.3 3.2 1.2 19.3 2.1 119.5 7.8 11.4 191.2 6.7 13.3 171.7 8.7 12.7 24.9 51.9 28.3 8.3 9.4 84.8 4.4 9.6 150.5 7.2 9.5 12.3 116.2 0.1 2.9 18.7 5.2 29.2 32.2 0.1 1.5 3.4 0.9 2.6 4.2 0.0 6.9 2.1 5.9 4.1 0.1 11.0 0.6 1.0 2.3 7.3 4.0 0.0 2.9 1.7 1.9 1.2 15.2 3.0 1.2 6.0 3.9 0.0 0.4 0.0 9.3 5.8 0.3 0.2 0.1 9.4 0.1 2.0 0.7 49.6 0.0 0.2 0.0 13.6 24.1 0.2 0.7 8.1 11.7 0.1 1.1 0.0 4.7 2.2 0.4 3.0 6.8 1.8 0.9 20.1 0.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 109.0 63.1 165.7 103.9 77.5 130.2 61.1 119.5 51.9 84.8 116.2 6.9 0.0 3.9 1101.2 1.1 10.5 0.0 0.0 1.8 376.6 0.2 0.6 188.5 0.0 1.3 20.2 479.6 0.1 0.0 0.0 15.6 0.0 111.2 36.4 6.0 6.4 66.0 0.0 1282.0 1.6 0.1 79.0 2.0 7.2 1.3 81.8 0.0 0.4 1.0 1431.8 1060.7 0.4 8.2 0.0 19.7 49.8 36.4 2.9 17.8 90.9 0.6 44.5 0.0 497.1 1351.0 0.1 5.0 30.1 0.9 0.4 0.1 127.9 0.8 484.4 6.6 24.3 26.5 2.3 1.5 0.8 9.5 0.0 1.9 2.6 0.3 0.2 ANKRD10 FLJ20093 ENSG00000088448 "Ankyrin repeat domain 10" Q9NXR5 13 110878540-110915069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034211, HPA038878, HPA038879" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB034211: AB_2058024, HPA038878: AB_2676252, HPA038879: AB_2676253" "unprognostic (3.29e-2)" "unprognostic (2.38e-1)" "unprognostic (9.26e-2)" "unprognostic (1.06e-1)" "unprognostic (2.89e-3)" "unprognostic (2.49e-1)" "unprognostic (4.97e-3)" "unprognostic (9.60e-2)" "unprognostic (1.16e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "unprognostic (2.92e-2)" "prognostic unfavorable (1.25e-6)" "unprognostic (1.95e-1)" "unprognostic (2.68e-1)" "unprognostic (8.32e-2)" "prognostic favorable (6.41e-6)" 78.2 60.3 61.9 42.2 69.8 88.7 75.6 65.9 85.2 109.1 71.4 97.2 43.8 87.4 89.9 37.6 90.7 53.5 74.3 62.6 68.8 93.9 84.1 91.7 63.3 72.5 65.8 99.6 94.9 25.5 97.5 36.4 75.5 108.1 50.2 77.6 70.3 42.4 176.6 48.9 88.1 49.0 66.3 138.9 75.0 40.8 67.7 52.4 82.1 73.4 50.4 79.2 68.3 80.1 36.1 29.6 66.7 56.2 50.2 48.4 29.6 24.0 50.0 23.5 28.9 31.0 68.8 49.5 51.1 18.2 38.2 81.1 29.2 22.6 31.7 119.1 43.2 59.0 73.3 64.9 20.0 85.9 49.4 46.2 33.7 16.5 24.4 49.1 32.1 48.8 26.4 33.1 64.2 10.8 49.9 95.3 37.0 79.1 18.3 76.0 24.5 49.6 64.9 39.4 53.2 39.7 18.2 31.7 39.9 49.7 22.7 108.0 28.0 27.6 23.0 13.7 24.7 40.8 46.9 28.9 51.7 41.5 44.2 39.0 25.8 22.7 30.4 21.1 26.3 42.9 29.2 25.3 33.8 44.7 30.9 33.7 16.1 31.8 22.3 31.5 39.9 26.8 61.9 69.8 65.9 85.2 62.6 68.8 72.5 65.8 75.5 66.3 67.7 80.1 77.6 16.0 65.4 83.6 69.3 94.3 39.0 25.9 129.1 33.3 72.2 55.0 32.0 45.8 45.3 38.6 54.2 45.1 54.4 43.4 19.6 52.1 8.5 59.0 79.2 83.3 41.9 30.3 118.7 49.2 51.8 78.3 51.5 105.4 30.4 65.3 40.7 48.8 46.6 32.0 105.8 55.2 57.0 46.5 99.7 7.3 39.1 60.4 72.9 145.2 44.7 28.6 35.0 158.3 203.6 38.7 46.2 51.6 58.5 62.5 40.9 45.1 40.8 55.4 52.6 105.6 88.8 28.0 23.6 44.3 77.7 38.9 58.9 44.9 59.6 53.2 ANKRD16 DKFZP434N1511 ENSG00000134461 "Ankyrin repeat domain 16" Q6P6B7 10 5861616-5889906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 26.9;Inhibitory neurons: 28.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037920, HPA037921" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA037920: AB_10671381, HPA037921: AB_2675740" "unprognostic (1.90e-1)" "unprognostic (1.67e-1)" "unprognostic (5.94e-3)" "unprognostic (2.15e-1)" "unprognostic (1.73e-2)" "unprognostic (6.18e-3)" "unprognostic (9.96e-3)" "unprognostic (4.57e-2)" "unprognostic (3.05e-1)" "unprognostic (1.86e-2)" "prognostic favorable (1.98e-4)" "unprognostic (5.85e-2)" "prognostic unfavorable (4.31e-7)" "unprognostic (1.06e-2)" "unprognostic (7.64e-2)" "unprognostic (9.53e-2)" "unprognostic (3.93e-2)" 3.8 4.0 5.5 2.3 5.5 1.9 4.1 5.6 7.9 6.3 3.1 3.7 3.2 5.1 4.9 3.7 5.8 2.5 3.3 5.2 4.2 3.5 4.1 3.0 3.1 5.0 4.5 6.2 4.1 5.7 3.9 1.7 5.2 4.1 2.5 4.4 4.0 3.1 3.9 6.7 3.2 3.2 4.0 3.2 6.6 8.7 4.8 3.8 3.7 2.6 3.3 4.3 4.4 5.6 8.3 9.8 4.5 9.2 4.6 3.4 6.6 2.5 1.9 4.4 3.8 12.1 4.3 8.8 3.5 4.2 1.6 8.5 5.5 6.4 2.0 3.1 8.6 5.5 4.8 11.1 5.9 3.4 3.8 5.3 4.8 4.0 3.1 3.5 4.9 9.0 7.5 2.6 3.1 11.5 12.7 5.8 3.7 11.2 6.9 9.6 2.9 18.1 5.0 5.3 2.7 6.0 5.2 6.4 6.0 3.6 8.9 6.9 3.2 2.6 3.4 5.8 3.5 14.7 7.1 5.8 5.4 3.3 2.9 0.3 0.2 0.0 0.1 0.1 0.1 0.3 0.1 0.2 0.2 0.4 0.4 0.1 0.1 0.4 0.1 0.5 0.2 0.1 5.5 5.5 5.6 7.9 5.2 4.2 5.0 4.5 5.2 4.0 4.8 5.6 5.3 3.2 1.3 14.7 5.9 4.7 7.8 1.4 4.6 14.1 7.0 6.0 2.8 10.0 1.8 3.7 6.2 4.7 3.0 2.4 13.7 2.1 8.4 7.8 9.8 4.2 4.2 5.5 25.1 2.2 3.6 10.2 4.1 4.4 0.0 13.0 3.3 3.8 3.3 26.9 28.4 3.1 0.0 1.0 3.3 14.6 5.6 3.2 3.6 5.6 3.6 8.8 1.0 12.5 16.2 1.0 1.3 3.8 11.3 7.3 5.2 8.3 1.0 14.4 0.0 8.5 4.5 13.0 7.8 6.5 5.7 1.5 3.5 10.5 5.2 3.7 ANKRD18A "FLJ35740, KIAA2015" ENSG00000180071 "Ankyrin repeat domain 18A" Q8IVF6 9 38571358-38620596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 18.2;brain: 21.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.3;Excitatory neurons: 24.8;Inhibitory neurons: 26.8;Oligodendrocytes: 118.1;Rod photoreceptor cells: 31.2;Spermatocytes: 53.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 17.9" "HPA046346, HPA046695, HPA049923, HPA051288" Uncertain Uncertain "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli, Nucleoli rim" Cytosol "HPA046346: AB_2679631, HPA046695: , HPA049923: AB_2680954, HPA051288: AB_2681421" "unprognostic (4.02e-2)" "unprognostic (1.07e-1)" "unprognostic (1.42e-3)" "unprognostic (1.69e-2)" "unprognostic (2.05e-1)" "unprognostic (2.38e-2)" "unprognostic (1.26e-1)" "unprognostic (2.37e-1)" "unprognostic (4.34e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-2)" "unprognostic (1.94e-5)" "unprognostic (2.31e-2)" "unprognostic (1.63e-2)" "unprognostic (1.58e-2)" "unprognostic (7.03e-2)" "unprognostic (2.14e-1)" 0.0 0.1 3.0 0.3 9.1 18.2 0.4 3.6 3.7 0.4 0.0 0.5 0.3 0.2 0.2 0.8 0.5 0.4 0.6 3.1 5.1 0.9 0.7 0.3 0.2 12.6 6.0 0.0 2.2 0.6 1.0 0.1 14.3 0.9 0.7 5.0 0.4 0.1 0.0 1.3 0.7 0.2 5.1 0.1 1.0 7.2 8.4 0.3 2.2 0.0 0.1 0.2 0.4 21.9 4.8 3.7 3.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.9 0.0 0.0 0.9 3.5 3.4 0.0 0.0 5.2 0.0 5.6 2.9 0.0 17.9 0.5 0.0 2.3 0.0 3.1 1.7 0.0 7.2 1.7 0.4 0.3 4.6 0.1 0.9 3.7 6.2 2.1 0.0 6.5 6.8 2.1 2.0 1.5 3.0 2.4 0.5 0.2 7.1 2.6 8.3 4.5 0.0 1.3 0.1 0.0 0.3 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.0 9.1 3.6 3.7 3.1 5.1 12.6 6.0 14.3 5.1 8.4 21.9 0.1 0.0 1.5 1.0 0.1 0.6 2.0 1.5 3.4 3.8 2.3 2.4 9.4 1.5 3.7 1.8 2.1 0.0 0.1 0.8 1.9 5.4 8.0 33.3 1.7 0.2 4.2 0.0 24.8 2.4 0.9 0.2 7.7 19.2 0.0 14.7 0.0 0.5 0.1 0.0 26.8 3.3 2.0 0.0 0.3 2.2 0.6 0.2 0.0 1.0 0.4 9.2 0.0 18.1 118.1 3.9 2.6 0.4 0.1 1.9 1.6 0.3 11.0 31.2 0.0 0.0 0.3 53.5 4.3 3.8 1.7 0.0 1.4 0.3 2.3 1.4 ANKRD18B bA255A11.3 ENSG00000230453 "Ankyrin repeat domain 18B" A2A2Z9 9 33524394-33573009 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 34.5;choroid plexus: 10.6" "Cell type enhanced" "Detected in many" "Early spermatids: 34.4;Excitatory neurons: 13.8;Muller glia cells: 22.3;Spermatocytes: 41.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 27.5" "HPA046346, HPA046695, HPA049923, HPA051288" Uncertain Uncertain "Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" Cytosol "HPA046346: AB_2679631, HPA046695: , HPA049923: AB_2680954, HPA051288: AB_2681421" "unprognostic (4.71e-2)" "unprognostic (1.85e-1)" "unprognostic (4.85e-3)" "unprognostic (1.00e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.29e-4)" "unprognostic (1.45e-2)" "unprognostic (9.84e-2)" "unprognostic (8.65e-2)" "unprognostic (2.54e-4)" "unprognostic (1.01e-2)" "unprognostic (6.43e-5)" "unprognostic (4.89e-2)" "unprognostic (9.75e-4)" "unprognostic (8.25e-2)" "unprognostic (5.18e-2)" 0.4 0.2 16.8 0.0 17.5 0.1 0.1 34.5 30.1 0.2 10.6 0.0 0.0 0.1 0.1 1.9 0.2 0.4 0.0 18.2 13.6 0.0 0.0 0.1 0.1 22.3 15.7 0.0 0.0 0.0 0.4 0.2 21.4 1.2 0.0 1.9 0.1 0.0 0.7 2.2 0.0 0.0 12.7 0.3 0.0 3.9 14.5 0.0 0.2 0.1 0.1 0.7 0.9 17.0 10.0 8.8 0.6 0.1 0.2 1.5 0.9 2.1 2.1 2.7 2.9 2.1 0.2 0.2 0.4 0.3 2.9 2.2 5.9 2.1 3.6 0.1 5.2 10.2 13.1 1.5 0.0 3.5 0.6 0.8 3.6 3.7 9.3 0.7 5.0 0.0 5.5 0.5 3.0 1.7 0.0 27.5 9.1 0.2 4.8 0.0 13.0 2.0 1.6 2.4 0.3 8.5 4.2 0.3 0.4 5.5 7.5 13.4 4.6 1.5 5.8 4.4 3.9 1.5 0.8 0.0 0.8 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 17.5 34.5 30.1 18.2 13.6 22.3 15.7 21.4 12.7 14.5 17.0 0.0 0.0 0.0 0.7 0.0 2.0 5.4 2.9 1.2 8.5 0.5 0.9 3.1 4.3 2.8 1.8 0.0 0.0 0.0 0.6 0.0 0.8 34.4 12.1 0.2 0.3 0.0 0.0 13.8 0.5 0.4 0.1 0.0 4.0 0.0 12.1 0.4 0.1 0.2 0.0 9.0 2.0 4.1 0.0 0.3 3.7 0.6 0.2 0.0 1.9 0.0 22.3 0.0 4.0 0.8 0.4 1.7 0.7 0.0 2.5 0.3 0.1 9.8 5.5 0.0 0.5 0.5 41.4 2.1 6.2 3.3 0.0 0.2 0.0 1.3 3.9 ANKRD2 ARPP ENSG00000165887 "Ankyrin repeat domain 2" Q9GZV1 10 97572499-97583884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 63 "heart muscle: 437.1;skeletal muscle: 981.2;tongue: 823.8" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 218.3" "Cancer enhanced" "Detected in many" "renal cancer: 4.9;testis cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 17.6;BJ hTERT+ SV40 Large T+: 7.3;HaCaT: 13.0;RPTEC TERT1: 17.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040842, HPA040884" Enhanced Enhanced Vesicles NA NA 110000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA040842: AB_10963794, HPA040884: AB_10969453" "unprognostic (1.27e-2)" "unprognostic (9.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-2)" "unprognostic (1.37e-1)" "unprognostic (1.61e-2)" "unprognostic (2.53e-1)" "unprognostic (5.60e-3)" "unprognostic (2.17e-1)" "unprognostic (3.12e-1)" "unprognostic (4.91e-2)" "unprognostic (2.22e-1)" "unprognostic (1.05e-2)" "unprognostic (3.69e-3)" "unprognostic (4.56e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" 0.4 0.8 2.5 0.1 2.3 0.0 0.5 2.5 3.7 0.2 2.0 0.3 0.0 0.3 0.3 1.0 0.1 0.3 437.1 2.5 2.7 11.8 0.3 0.8 0.2 2.5 2.4 0.1 0.9 0.0 0.6 0.0 2.5 2.9 0.0 0.3 3.4 0.9 981.2 2.7 0.2 0.2 1.9 0.1 0.2 0.5 2.7 0.0 0.5 823.8 0.1 0.1 0.4 2.5 17.6 5.4 0.0 0.0 0.2 0.0 0.4 0.9 0.0 7.3 4.7 0.3 5.3 0.0 0.6 0.2 0.4 13.0 0.0 4.7 5.0 0.2 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.8 2.1 4.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 17.4 0.8 0.0 0.0 0.0 4.4 0.0 0.4 2.1 0.3 0.0 0.1 1.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.5 3.7 2.5 2.7 2.5 2.4 2.5 1.9 2.7 2.5 0.1 0.0 0.0 1.3 0.0 0.1 0.7 1.7 1.2 0.0 0.2 0.4 218.3 2.8 0.2 3.7 0.0 0.2 0.0 0.0 31.3 1.2 0.6 0.1 0.3 1.6 0.0 0.0 1.3 0.2 0.4 1.0 0.0 0.1 0.0 0.7 0.4 0.2 0.1 0.0 1.5 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.5 0.4 0.9 0.0 1.9 0.0 0.1 0.0 19.1 0.0 0.1 0.0 13.6 1.1 2.5 3.5 0.6 0.3 0.3 0.2 0.1 0.0 0.5 ANKRD22 MGC22805 ENSG00000152766 "Ankyrin repeat domain 22" Q5VYY1 10 88819896-88851844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.8;skin 1: 30.9;stomach 1: 46.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 37.2;Distal enterocytes: 38.2;Gastric mucus-secreting cells: 49.5;Paneth cells: 51.5;Squamous epithelial cells: 35.8;Suprabasal keratinocytes: 102.9;Urothelial cells: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 6.4" "Group enriched" "Detected in many" 14 "granulocytes: 6.4;monocytes: 3.1" "Cell line enhanced" "Detected in some" "A-431: 8.6;CAPAN-2: 26.1;HL-60: 9.4;NB-4: 8.7;OE19: 20.9;RT4: 16.4;T-47d: 12.2;U-937: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA012922 Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA012922: AB_1844838" "unprognostic (1.86e-1)" "unprognostic (1.48e-3)" "unprognostic (9.73e-3)" "prognostic favorable (8.73e-6)" "unprognostic (1.18e-1)" "unprognostic (2.81e-2)" "unprognostic (2.39e-2)" "unprognostic (1.50e-1)" "unprognostic (4.57e-2)" "unprognostic (7.21e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (1.09e-3)" "unprognostic (1.05e-2)" "unprognostic (4.87e-3)" "unprognostic (4.17e-2)" "unprognostic (3.18e-3)" "unprognostic (1.01e-3)" 0.2 0.3 0.6 9.5 0.7 5.4 2.6 0.5 0.9 7.6 0.4 7.2 2.7 0.2 0.3 33.8 0.3 3.2 0.1 0.5 0.7 4.7 2.0 1.5 4.2 1.3 0.8 0.3 12.9 0.8 0.3 0.2 1.1 2.5 7.1 0.1 4.9 0.1 0.1 30.9 2.1 1.6 0.6 6.4 46.3 0.1 0.7 5.5 0.1 0.0 7.8 4.8 13.9 0.9 8.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.1 0.0 0.0 6.5 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.4 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.6 8.7 0.0 20.9 0.1 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 1.3 0.0 0.0 12.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 7.9 0.0 0.0 2.1 1.1 0.0 3.1 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 6.4 0.2 0.6 0.2 0.0 0.6 0.6 0.7 0.5 0.9 0.5 0.7 1.3 0.8 1.1 0.6 0.7 0.9 0.0 0.0 3.7 0.0 1.0 37.2 18.6 7.6 1.8 0.0 1.5 0.9 0.2 5.7 4.5 7.3 0.0 0.0 0.0 38.2 0.0 3.2 0.0 0.9 0.5 0.3 1.8 0.4 0.0 5.9 0.0 0.6 49.5 4.8 0.0 0.0 0.0 0.6 2.2 0.0 0.0 14.9 16.2 9.3 3.1 0.2 0.3 8.5 1.8 0.0 2.2 0.0 0.0 0.0 0.0 5.7 51.5 0.0 0.2 10.1 0.6 0.0 1.7 0.0 0.0 0.1 0.3 0.1 0.2 35.8 102.9 0.0 0.8 0.1 25.7 30.3 ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 56.4;Fibroblasts: 31.2;Leydig cells: 36.4;Muller glia cells: 57.7;Peritubular cells: 50.8;Skeletal myocytes: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.6;THP-1: 6.8;TIME: 8.4;U-87 MG: 8.3;U-937: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA035453: AB_10672864" "prognostic favorable (9.35e-4)" "prognostic favorable (2.90e-4)" "unprognostic (2.07e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (5.86e-2)" "unprognostic (9.29e-10)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (5.92e-2)" "unprognostic (8.69e-3)" 4.0 1.3 8.2 1.1 7.9 0.3 4.6 7.6 9.7 20.6 6.4 6.0 0.5 5.8 1.4 24.7 6.6 1.3 2.9 7.5 8.6 0.8 2.5 2.3 0.4 8.7 9.5 4.4 0.7 0.0 2.0 0.1 8.5 6.6 0.8 1.3 11.4 2.7 8.2 60.8 2.5 2.1 8.4 0.5 3.9 1.6 9.0 0.5 1.7 3.8 6.7 7.3 20.6 7.6 0.1 0.0 0.0 0.0 2.2 9.6 0.2 1.4 3.6 0.4 1.2 0.4 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 1.1 2.9 0.1 3.3 0.4 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.2 0.0 0.0 3.9 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.5 0.0 0.0 2.1 0.0 0.7 0.8 0.1 0.0 0.3 1.1 0.3 0.0 0.2 0.7 0.1 0.7 0.2 0.5 0.7 0.7 8.2 7.9 7.6 9.7 7.5 8.6 8.7 9.5 8.5 8.4 9.0 7.6 1.6 0.0 0.0 6.8 0.3 4.6 16.8 10.2 0.0 1.1 6.3 13.5 1.5 2.8 9.5 1.8 0.0 0.1 2.2 0.0 0.0 0.0 3.5 56.4 10.9 1.3 0.0 2.7 5.6 0.4 0.1 31.2 0.5 17.2 19.1 0.0 2.2 13.9 11.0 0.0 2.1 0.0 14.2 1.2 4.6 5.9 36.4 1.1 5.4 1.0 1.1 57.7 5.2 3.0 0.6 0.1 0.0 50.8 0.4 5.3 0.0 0.1 9.8 2.7 0.0 29.5 6.4 0.1 1.0 10.4 12.4 0.3 5.5 1.1 0.0 13.6 ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 266.0" "Group enriched" "Detected in many" 5 "Early spermatids: 156.4;Oligodendrocytes: 441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBF TERT88: 655.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" 1.2 0.7 59.8 5.2 134.5 36.4 2.0 125.1 72.7 1.8 18.4 6.0 4.4 1.8 0.2 10.4 0.9 2.1 0.8 59.3 83.6 0.4 1.2 1.4 6.7 162.3 106.5 0.9 0.6 0.2 0.2 8.9 160.2 0.9 8.0 0.3 1.7 0.4 0.3 13.6 4.3 14.9 99.2 1.2 4.8 12.4 102.3 16.0 0.8 0.3 9.5 3.2 3.2 266.0 476.1 96.5 79.3 61.0 10.7 26.9 85.6 292.5 169.3 344.4 256.0 66.4 142.7 23.9 82.1 148.6 182.8 237.0 63.4 170.7 655.4 16.1 46.0 32.7 104.8 55.8 1.7 47.3 36.7 6.0 7.7 225.3 147.2 40.8 109.3 31.2 69.6 48.8 284.4 71.0 40.0 54.8 88.5 71.9 102.3 29.1 238.2 15.9 76.5 76.5 33.5 39.5 154.1 175.8 26.1 109.6 119.0 53.6 104.5 214.2 239.0 127.6 346.6 20.1 34.2 43.2 72.9 74.9 460.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 59.8 134.5 125.1 72.7 59.3 83.6 162.3 106.5 160.2 99.2 102.3 266.0 0.4 0.0 1.1 2.3 1.0 14.1 1.9 8.3 7.4 0.0 1.9 2.0 0.6 0.0 3.2 0.0 0.0 13.8 1.1 2.8 0.0 0.7 156.4 18.9 3.2 1.9 0.0 35.3 3.4 0.2 23.2 6.9 10.2 12.8 0.0 15.4 1.1 0.5 9.8 0.0 5.7 3.4 6.1 1.6 5.9 53.3 1.2 2.7 0.0 0.0 0.0 0.0 0.0 1.5 441.3 0.6 0.1 0.0 8.8 1.6 0.8 0.3 10.4 0.0 0.0 0.4 5.2 20.0 17.7 27.1 9.2 2.9 2.6 1.7 6.0 3.3 ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 181.7;salivary gland: 180.5;seminal vesicle: 209.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 70.2;Early spermatids: 54.9;Hepatocytes: 141.3;Late spermatids: 75.1;Sertoli cells: 46.0;Smooth muscle cells: 52.5;Suprabasal keratinocytes: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 140.2;CAPAN-2: 207.9;HaCaT: 254.0;OE19: 182.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 6.6" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" 16.3 2.2 0.3 3.6 1.6 0.1 86.8 0.8 1.3 46.7 0.1 14.3 3.6 40.0 181.7 12.7 59.1 54.4 21.9 0.5 0.1 6.4 108.5 16.1 3.4 1.0 0.2 2.9 9.1 48.0 4.4 5.2 1.1 17.1 11.0 0.9 180.5 209.2 12.7 97.4 4.6 30.1 0.2 1.2 48.3 10.4 0.1 1.5 35.4 33.0 4.0 6.7 12.8 0.5 140.2 5.3 0.3 4.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 207.9 0.0 2.5 0.0 0.3 254.0 0.0 0.7 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.0 1.0 0.5 0.3 1.1 182.2 19.6 0.3 0.0 0.7 0.0 0.2 7.3 0.2 0.1 43.1 0.8 1.4 16.2 0.5 0.5 0.3 1.1 0.0 3.5 0.1 0.3 0.2 0.2 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.8 1.3 0.5 0.1 1.0 0.2 1.1 0.2 0.1 0.5 7.2 0.0 0.0 0.7 0.4 17.7 21.5 4.2 0.0 0.0 30.5 70.2 3.5 17.2 2.0 0.0 0.0 1.3 0.2 0.4 0.0 4.1 54.9 10.0 27.5 5.6 0.0 2.7 0.7 0.0 0.6 4.2 36.7 18.5 4.5 0.0 3.3 141.3 0.2 0.0 20.4 13.3 0.0 1.6 3.0 75.1 1.8 0.7 5.4 2.8 0.0 0.8 0.0 1.5 0.7 1.0 0.5 1.5 0.3 22.6 0.0 0.7 0.3 0.4 46.0 1.1 52.5 1.4 2.3 1.4 46.7 4.1 0.7 0.1 0.4 20.9 ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 226.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 81.3;Early spermatids: 57.3;Late spermatids: 283.2;Microglial cells: 143.4;Rod photoreceptor cells: 179.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.6;HUVEC TERT2: 9.5;U-2 OS: 24.1" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 9: U-2 OS - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" 8.8 0.3 3.8 0.4 4.4 0.0 6.6 2.2 3.3 4.3 5.0 1.9 0.7 1.8 1.4 1.7 3.2 1.1 8.0 2.5 2.4 1.2 0.2 7.2 0.1 3.2 3.2 1.5 0.9 1.3 0.6 4.1 3.4 2.5 0.6 226.0 1.3 1.0 2.0 1.1 1.7 1.5 3.0 3.4 2.2 10.1 3.9 0.3 2.4 4.4 0.2 2.4 3.5 2.8 2.5 0.0 4.4 0.0 0.0 0.2 2.0 0.0 9.6 0.5 1.0 0.0 0.2 0.2 0.3 0.0 0.1 0.3 0.0 0.1 0.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 1.9 0.0 1.0 0.0 0.0 4.6 2.3 0.0 1.9 0.0 1.0 0.1 0.1 0.0 0.0 2.3 1.6 0.0 3.9 1.3 0.0 0.2 0.0 24.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 4.4 2.2 3.3 2.5 2.4 3.2 3.2 3.4 3.0 3.9 2.8 9.7 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.6 11.5 0.3 0.1 1.9 0.0 0.0 0.0 81.3 1.4 0.0 0.0 0.0 0.0 57.3 0.4 0.4 9.1 0.0 0.0 1.7 0.0 2.0 0.3 0.0 0.5 0.0 0.0 4.6 0.0 0.2 10.1 2.0 0.0 0.0 0.0 0.0 283.2 0.3 0.1 0.0 143.4 0.0 13.0 0.0 31.2 9.9 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 179.9 0.0 1.3 0.6 1.4 1.8 0.0 0.1 2.5 0.0 0.2 0.2 0.0 ANO5 "GDD1, LGMD2L, TMEM16E" ENSG00000171714 "Anoctamin 5" Q75V66 11 21799934-22283357 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 24.9;parathyroid gland: 17.0;skeletal muscle: 65.5;tongue: 50.4" "Group enriched" "Detected in many" 7 "Astrocytes: 67.9;Cardiomyocytes: 86.2;Excitatory neurons: 166.6;Inhibitory neurons: 136.4;Oligodendrocyte precursor cells: 81.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.9;HAP1: 5.0;HEK 293: 6.6;NTERA-2: 3.5;RPTEC TERT1: 3.2;U-266/84: 3.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058857 Uncertain NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058857: AB_2683835" "unprognostic (5.25e-3)" "unprognostic (1.36e-3)" "unprognostic (2.43e-1)" "unprognostic (7.67e-3)" "unprognostic (3.50e-2)" "unprognostic (5.85e-2)" "unprognostic (8.17e-3)" "unprognostic (2.30e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.54e-4)" "unprognostic (8.55e-2)" "prognostic favorable (2.50e-7)" "unprognostic (3.65e-3)" "unprognostic (2.84e-1)" "unprognostic (2.77e-4)" "unprognostic (7.94e-2)" 0.9 4.5 1.9 0.8 3.0 0.0 0.7 0.1 8.9 1.6 3.0 2.6 3.3 1.5 1.3 2.0 0.8 1.7 24.9 4.0 2.2 3.6 2.1 1.2 0.2 2.7 2.1 0.5 3.9 17.0 3.4 0.0 2.2 4.2 3.3 2.1 2.6 4.1 65.5 0.1 2.5 2.7 0.4 0.7 3.0 1.8 2.4 0.2 4.7 50.4 0.3 2.0 0.3 3.4 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.3 1.4 2.5 0.0 0.0 0.0 0.0 3.5 2.6 0.0 0.0 0.0 0.0 3.2 0.1 2.7 2.6 0.0 0.0 0.0 2.1 2.1 1.9 0.0 0.0 1.9 0.0 0.0 2.0 3.7 0.0 2.8 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 3.0 0.1 8.9 4.0 2.2 2.7 2.1 2.2 0.4 2.4 3.4 0.4 0.0 5.9 67.9 0.6 0.3 0.3 0.0 0.0 6.7 2.2 0.6 86.2 1.5 0.0 1.8 0.0 0.1 0.0 7.8 1.9 1.3 5.8 0.4 0.2 3.2 5.4 0.4 166.6 2.7 0.0 3.0 1.5 0.3 0.0 3.0 2.5 5.1 0.5 1.7 136.4 7.1 0.0 0.6 1.4 2.9 0.0 1.6 1.8 14.0 1.9 2.8 0.0 81.4 4.2 1.0 4.4 1.2 0.0 1.4 2.7 3.3 0.7 0.8 0.0 8.1 2.4 11.0 0.9 0.1 0.1 0.0 0.2 1.6 4.6 0.2 ANOS1 "ADMLX, KAL, KAL1, KALIG-1, WFDC19" ENSG00000011201 "Anosmin 1" P23352 X 8528874-8732137 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.1" "Cell type enriched" "Detected in many" 11 "Alveolar cells type 1: 240.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 40.4;NTERA-2: 37.0;U-2 OS: 17.6" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.93e-1)" "unprognostic (5.33e-2)" "unprognostic (9.54e-2)" "unprognostic (4.16e-3)" "unprognostic (7.77e-3)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" "unprognostic (1.17e-3)" "unprognostic (4.53e-2)" "unprognostic (6.43e-2)" "unprognostic (2.09e-2)" "unprognostic (6.24e-2)" "unprognostic (1.71e-2)" "unprognostic (9.38e-3)" "unprognostic (6.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.56e-2)" 6.6 4.0 7.6 1.1 10.5 0.3 3.7 6.0 7.3 4.4 0.9 0.6 0.3 0.5 3.1 1.3 1.1 1.7 5.0 8.3 12.2 0.8 0.8 43.1 1.9 13.8 11.5 0.3 0.4 15.1 0.5 1.2 14.8 4.1 1.0 19.6 2.4 4.4 10.5 3.1 0.6 0.7 18.6 0.8 0.8 3.9 12.6 4.0 9.3 6.8 0.9 1.2 1.2 17.9 0.1 0.0 1.9 0.0 0.0 0.0 2.2 0.8 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.7 4.0 0.2 5.5 0.5 5.6 0.0 0.0 0.0 1.5 0.1 3.1 0.3 0.1 40.4 0.0 0.1 0.0 0.0 0.5 0.4 0.3 0.0 37.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 2.1 0.1 1.9 0.5 0.0 4.8 0.0 1.0 0.0 0.0 17.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 10.5 6.0 7.3 8.3 12.2 13.8 11.5 14.8 18.6 12.6 17.9 1.7 240.4 12.6 0.0 0.0 0.0 4.7 0.0 13.1 20.5 6.2 3.4 6.2 0.0 19.8 0.0 4.2 0.1 0.0 0.0 0.0 0.9 0.2 0.4 1.5 1.6 0.0 0.0 0.0 0.0 0.3 10.9 0.0 0.1 1.3 2.2 6.1 0.0 5.1 0.0 0.0 0.0 0.0 2.9 0.0 0.3 0.6 3.0 0.0 0.0 0.2 17.8 0.0 0.0 0.0 1.5 0.1 1.2 0.0 3.1 0.0 0.2 3.6 1.6 0.0 8.7 3.3 0.6 1.6 1.5 0.0 0.1 0.3 0.8 0.4 1.1 ANXA8 ANX8 ENSG00000265190 "Annexin A8" P13928 10 47460162-47484158 "Predicted intracellular proteins" "Blood coagulation, Hemostasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 217.6;skin 1: 266.2;vagina: 110.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 99.3;Astrocytes: 38.8;Club cells: 40.7;Excitatory neurons: 47.8;Fibroblasts: 34.5;Inhibitory neurons: 41.0;Microglial cells: 35.6;Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 48.1;Squamous epithelial cells: 63.6" "Group enriched" "Detected in many" 4 "cervical cancer: 14.3;head and neck cancer: 16.1;lung cancer: 4.3;urothelial cancer: 11.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 394.3;HBEC3-KT: 622.3;hTCEpi: 357.6;hTERT-HME1: 134.2;RT4: 159.6" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (8.32e-4)" "unprognostic (2.52e-1)" "unprognostic (2.44e-1)" "unprognostic (6.15e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (5.94e-2)" "unprognostic (2.88e-2)" "unprognostic (2.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.19e-1)" "unprognostic (7.55e-15)" "unprognostic (1.04e-2)" "unprognostic (9.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.39e-1)" 73.3 0.7 0.5 0.1 0.5 0.7 11.7 0.7 1.1 49.6 0.6 0.5 0.0 0.1 1.0 217.6 3.7 0.4 4.4 0.6 0.3 0.0 1.8 13.1 0.0 1.0 0.8 1.3 0.3 0.0 0.3 30.9 0.8 12.4 0.1 0.0 47.3 9.8 0.4 266.2 0.2 0.0 0.6 0.2 0.4 0.8 1.5 4.8 0.2 0.2 46.6 66.4 110.7 0.9 123.4 16.2 0.0 0.0 0.0 0.0 33.7 2.3 0.3 0.0 0.0 8.7 35.0 0.0 2.5 1.0 1.8 394.3 0.0 622.3 0.0 27.9 0.0 0.0 39.6 0.0 26.2 0.0 1.3 0.2 357.6 0.2 134.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 37.2 0.1 4.0 0.0 0.0 0.5 0.0 0.0 159.6 0.0 0.0 56.4 16.4 0.3 8.7 0.1 3.5 0.0 0.0 39.5 0.7 2.4 0.2 0.1 0.2 4.4 0.3 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.5 0.7 1.1 0.6 0.3 1.0 0.8 0.8 0.6 1.5 0.9 0.1 99.3 7.3 38.8 0.0 1.1 10.3 1.6 2.8 0.0 4.9 3.4 2.6 7.2 40.7 3.7 0.0 14.7 0.1 1.0 0.0 3.1 0.6 2.1 0.0 0.5 0.0 0.0 47.8 0.4 6.7 34.5 0.0 0.2 1.3 0.1 0.0 0.0 0.6 0.0 41.0 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.0 35.6 0.1 0.0 0.0 50.8 48.1 17.3 0.0 0.0 0.0 8.5 1.5 0.0 14.2 0.0 0.0 0.0 0.6 0.2 1.4 63.6 2.0 6.2 0.3 0.1 0.2 17.2 ANXA8L1 "ANXA8L2, bA145E20.2, bA301J7.3" ENSG00000264230 "Annexin A8 like 1" Q5VT79 10 46375627-46391784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 195.2;skin 1: 325.4;vagina: 100.5" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 118.7" "Cancer enhanced" "Detected in many" "cervical cancer: 5.2;head and neck cancer: 5.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 374.5;HBEC3-KT: 485.0;hTCEpi: 140.1;SiHa: 116.6" "HPA045246, HPA047451" Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA045246: AB_2679271, HPA047451: AB_2680052" "unprognostic (3.67e-3)" "unprognostic (4.56e-3)" "unprognostic (9.14e-3)" "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.27e-2)" "unprognostic (1.08e-2)" "unprognostic (8.05e-2)" "unprognostic (6.94e-3)" "unprognostic (8.33e-5)" "unprognostic (3.43e-1)" "unprognostic (8.26e-10)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" 39.8 0.2 0.0 0.0 0.0 1.2 21.9 0.0 0.1 45.2 0.0 0.3 0.0 0.1 0.0 195.2 6.1 0.1 2.9 0.0 0.0 0.0 1.1 16.5 0.0 0.0 0.0 0.9 0.3 0.0 0.2 24.1 0.0 6.8 0.0 0.0 40.8 4.5 1.1 325.4 0.1 0.0 0.0 0.1 0.3 0.8 0.0 4.3 0.1 0.0 35.1 37.4 100.5 0.0 70.1 18.2 0.0 0.0 0.0 0.0 24.8 0.9 0.1 0.0 0.0 1.9 12.6 0.0 0.6 0.3 0.5 374.5 0.0 485.0 0.0 28.9 0.0 0.0 33.3 0.0 9.3 0.0 0.7 0.0 140.1 0.2 58.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 70.2 0.2 0.7 0.0 0.0 0.8 0.0 0.0 76.0 0.1 0.0 116.6 12.0 0.0 7.2 0.0 0.7 0.0 0.1 12.2 0.1 0.3 0.0 0.1 0.0 2.8 0.1 0.2 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.9 1.1 0.0 0.0 0.0 3.0 0.2 11.4 1.6 2.3 2.4 3.7 18.6 19.9 0.0 0.0 14.8 0.0 3.0 0.0 0.7 0.4 1.0 0.0 0.9 0.0 0.0 0.0 0.2 11.4 12.8 5.6 0.1 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 9.7 1.4 0.0 1.2 2.5 5.2 0.0 10.9 0.2 13.1 0.0 1.5 0.3 2.4 118.7 1.1 6.3 0.6 0.0 0.2 5.9 ANXA9 ANX31 ENSG00000143412 "Annexin A9" O76027 1 150982249-150995634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 61.5;Collecting duct cells: 12.9;Ductal cells: 21.2;Hepatocytes: 17.4;Proximal tubular cells: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.6" "Group enriched" "Detected in many" 4 "dendritic cells: 1.6;granulocytes: 1.0;monocytes: 1.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 40.6;Hep G2: 42.3;MCF7: 59.2;OE19: 47.8;T-47d: 139.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028404, HPA028698" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Cytosol" "HPA028404: AB_10599190, HPA028698: AB_10600227" "unprognostic (4.06e-1)" "unprognostic (1.55e-2)" "unprognostic (3.15e-3)" "unprognostic (2.08e-3)" "unprognostic (2.93e-2)" "unprognostic (4.49e-2)" "unprognostic (1.84e-2)" "unprognostic (3.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "unprognostic (2.97e-1)" "prognostic favorable (8.74e-6)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (8.99e-2)" "unprognostic (1.72e-2)" 3.2 3.7 2.6 2.6 7.1 2.4 6.9 6.1 3.5 2.2 3.3 2.1 4.6 6.4 5.9 26.2 4.7 9.2 6.0 1.7 3.5 22.0 29.9 3.1 2.3 9.0 6.7 4.7 35.8 19.2 1.2 1.0 7.9 2.4 0.3 7.2 7.5 21.2 3.8 32.4 4.2 2.9 4.5 2.8 4.2 3.8 5.3 0.5 25.0 0.2 23.2 6.3 6.0 12.1 11.7 2.8 4.2 4.4 0.0 0.0 11.4 1.0 0.8 0.1 0.0 33.9 40.6 0.4 2.5 0.0 1.3 6.8 0.0 0.8 0.1 3.9 4.4 6.1 4.7 42.3 0.0 2.4 2.6 0.0 0.3 0.1 0.2 9.5 0.0 1.8 3.0 13.2 0.1 59.2 0.5 3.2 1.1 47.8 0.8 2.8 0.6 15.0 0.1 17.0 6.4 3.6 2.6 28.8 1.7 2.3 139.9 3.7 4.7 0.9 1.3 0.7 0.8 4.0 13.0 18.8 6.2 4.2 3.3 0.0 1.2 0.7 0.0 0.7 0.3 0.2 0.1 0.2 1.6 0.0 0.3 0.0 1.0 0.0 0.1 0.0 0.0 0.4 2.6 7.1 6.1 3.5 1.7 3.5 9.0 6.7 7.9 4.5 5.3 12.1 0.1 0.0 1.1 0.3 0.2 0.1 0.4 0.8 0.0 0.0 4.5 2.5 0.4 61.5 4.5 12.9 0.0 2.0 0.1 0.0 3.9 21.2 1.5 1.3 0.8 0.1 0.0 0.0 0.2 7.5 0.3 0.6 0.0 1.6 1.3 0.0 0.0 17.4 2.2 0.0 0.2 0.0 0.0 0.6 0.4 0.9 1.5 1.4 1.8 0.0 0.2 0.0 0.0 1.0 0.5 2.9 0.1 1.2 0.0 0.3 0.3 44.6 2.5 0.0 0.0 0.1 0.3 4.9 0.2 0.3 0.0 1.5 0.2 0.0 0.3 5.4 AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 162.0;Proximal tubular cells: 373.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.6" "Cell line enhanced" "Detected in many" "CACO-2: 172.8;Hep G2: 313.8;MCF7: 268.3;OE19: 156.7;RT4: 164.9;U-2 OS: 166.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA054999 Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA054999: AB_2682666" "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" 3.4 0.1 0.8 6.4 0.3 0.9 32.9 0.6 0.8 27.1 0.3 67.1 64.0 6.6 61.8 51.9 46.6 22.7 0.4 0.5 0.4 76.3 1.5 19.2 0.4 0.7 0.6 0.3 55.9 62.4 34.8 16.2 0.4 30.8 63.4 0.1 41.5 24.0 0.3 42.1 54.8 3.0 0.3 0.6 59.1 9.6 0.7 4.2 58.8 0.3 9.5 23.4 19.1 0.6 144.2 71.1 0.4 10.4 0.0 0.0 65.0 0.2 0.0 2.3 1.6 172.8 82.1 0.4 64.7 1.2 43.4 97.6 0.1 109.0 3.2 0.6 1.0 6.7 48.5 313.8 1.3 0.3 0.8 0.2 81.6 3.9 0.1 5.0 0.0 0.4 0.3 0.6 1.2 268.3 0.6 1.8 31.4 156.7 0.0 2.4 9.3 0.7 2.7 164.9 67.3 0.2 0.0 120.0 0.6 34.6 123.3 0.4 0.0 0.4 166.7 0.9 2.2 0.4 0.9 1.4 0.2 0.4 0.2 4.3 0.4 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.6 0.0 1.4 0.2 0.0 2.7 0.8 0.3 0.6 0.8 0.5 0.4 0.7 0.6 0.4 0.3 0.7 0.6 0.4 28.9 34.8 0.0 1.9 6.9 19.2 68.9 13.1 0.0 49.3 30.0 0.5 47.1 64.2 86.5 0.0 123.0 0.5 112.2 137.0 141.3 43.4 52.4 5.4 1.7 74.4 0.0 0.3 115.8 101.0 1.5 73.4 57.7 2.5 0.0 0.7 0.0 9.8 0.0 0.2 95.5 97.6 0.8 0.0 19.9 1.5 2.6 3.6 0.0 1.7 0.0 0.0 0.0 0.2 130.2 125.6 0.7 0.0 37.6 162.0 373.6 61.5 0.0 0.0 0.0 6.2 16.9 4.1 39.1 13.1 66.1 2.8 0.0 131.4 48.3 AP1S1 "AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2" ENSG00000106367 "Adaptor related protein complex 1 subunit sigma 1" P61966 7 101154456-101161596 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Ichthyosis, Mental retardation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 344.4;Proximal enterocytes: 241.3;Proximal tubular cells: 304.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060945 Supported Supported "Golgi apparatus,Vesicles" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" "HPA060945: AB_2684393" "unprognostic (1.98e-2)" "unprognostic (5.41e-3)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-3)" "unprognostic (8.70e-3)" "unprognostic (7.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.76e-1)" "unprognostic (7.79e-2)" "unprognostic (1.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" 14.4 24.6 72.2 13.9 75.7 5.8 17.2 43.7 82.6 18.3 34.6 28.6 39.0 16.9 17.0 34.2 13.8 12.8 11.8 85.2 59.6 41.2 36.2 14.7 11.9 53.6 51.9 13.5 21.9 22.8 31.0 15.9 53.4 22.2 22.4 14.6 20.3 9.3 6.4 39.2 30.3 12.7 46.1 20.2 22.0 16.4 62.5 19.1 15.2 8.5 13.6 20.1 19.5 62.7 121.0 87.3 63.3 118.4 42.8 70.4 138.2 76.8 51.1 50.8 52.8 47.3 147.5 24.9 127.5 84.6 97.1 59.0 35.3 116.0 45.6 57.0 56.6 16.8 52.0 61.4 54.2 46.8 87.7 79.1 91.0 49.4 20.6 76.7 76.8 54.1 56.7 103.2 129.9 292.1 40.4 107.8 97.8 177.0 188.2 24.9 27.2 54.6 127.8 88.8 47.5 157.7 40.4 121.1 151.4 101.6 50.7 46.8 79.0 74.1 132.3 27.6 55.2 21.4 51.4 48.4 195.2 50.1 152.9 0.5 3.3 0.3 2.3 3.1 2.2 2.6 3.2 2.5 4.6 2.0 1.9 1.8 1.2 1.3 1.8 5.0 3.3 2.4 72.2 75.7 43.7 82.6 85.2 59.6 53.6 51.9 53.4 46.1 62.5 62.7 34.4 6.4 0.0 2.3 17.9 38.7 29.7 173.0 46.7 30.7 54.8 49.0 1.1 45.8 72.9 55.2 8.4 170.7 19.8 88.4 344.4 128.2 2.5 28.8 34.2 36.7 90.3 16.2 21.2 111.7 101.3 27.7 42.8 31.9 5.7 85.3 28.9 43.0 95.2 30.3 10.3 96.5 116.0 24.8 21.6 3.4 35.1 27.3 53.4 7.5 58.0 34.1 17.5 2.5 9.8 183.3 86.1 21.8 17.4 34.9 241.3 304.8 34.9 22.3 19.7 11.4 38.4 13.1 70.9 51.4 45.5 60.5 19.5 157.4 119.9 38.2 AP5Z1 "KIAA0415, SPG48, zeta" ENSG00000242802 "Adaptor related protein complex 5 subunit zeta 1" O43299 7 4775615-4794397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035693 Supported Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Nucleoplasm "HPA035693: AB_10960687" "unprognostic (1.64e-1)" "unprognostic (5.22e-2)" "unprognostic (3.01e-3)" "unprognostic (4.24e-2)" "unprognostic (2.43e-3)" "unprognostic (5.19e-1)" "prognostic unfavorable (1.35e-5)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-3)" "unprognostic (1.26e-2)" "unprognostic (5.32e-3)" "unprognostic (8.28e-2)" "unprognostic (1.71e-1)" "unprognostic (1.95e-2)" "unprognostic (2.22e-1)" 14.8 18.5 7.0 0.7 7.1 1.5 11.8 7.3 10.0 12.4 5.8 13.2 1.1 13.4 1.0 11.0 11.0 0.8 7.7 6.9 5.7 9.2 9.2 12.9 1.8 8.3 6.5 11.8 9.9 0.7 9.8 1.1 7.4 11.7 0.4 0.6 12.4 0.7 8.5 21.8 15.5 0.4 5.9 22.9 12.0 8.6 7.4 0.9 11.2 0.2 0.6 13.4 10.9 7.3 2.8 4.2 0.7 2.4 1.0 0.9 4.3 1.3 1.9 2.0 1.7 5.2 3.5 1.6 1.8 0.9 5.1 5.4 0.7 0.5 0.6 1.8 3.5 2.4 4.5 4.6 3.0 2.5 5.1 2.2 1.6 1.8 1.3 0.7 0.5 2.2 3.4 1.1 1.2 7.7 0.3 15.0 5.9 0.3 4.3 2.9 2.6 4.8 1.0 4.4 1.7 3.0 1.8 8.7 6.4 0.5 6.4 8.9 3.8 2.3 4.4 6.5 1.7 8.5 7.4 2.3 1.7 5.6 3.6 1.9 2.3 2.9 2.4 2.8 1.4 1.9 1.8 2.4 1.2 1.8 2.5 2.2 2.2 2.4 2.5 2.4 1.8 1.3 7.0 7.1 7.3 10.0 6.9 5.7 8.3 6.5 7.4 5.9 7.4 7.3 12.4 9.6 15.0 7.5 18.2 6.9 2.9 8.8 8.0 10.5 5.7 5.8 4.3 15.7 6.6 11.0 4.2 11.5 20.3 20.1 0.0 14.1 2.2 9.9 10.1 11.6 12.0 5.0 12.4 13.6 7.7 9.9 21.4 16.4 17.1 14.3 12.5 8.1 28.7 18.5 10.7 15.1 10.2 12.3 10.7 1.5 13.4 16.3 14.2 13.1 23.4 8.2 21.6 10.6 12.6 20.6 15.9 10.9 19.8 4.9 14.7 6.8 8.3 9.4 0.0 5.8 9.5 8.1 10.8 7.6 11.1 16.6 15.6 12.6 14.1 3.8 APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000363-55009057 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: AB_2680448" "unprognostic (2.90e-2)" "prognostic favorable (6.17e-4)" "unprognostic (4.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (5.62e-2)" "prognostic unfavorable (6.13e-7)" "unprognostic (5.89e-2)" "unprognostic (4.87e-2)" "prognostic favorable (5.21e-4)" "unprognostic (7.46e-2)" "unprognostic (3.16e-1)" "unprognostic (6.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.63e-4)" 7.2 8.9 6.1 8.8 6.3 10.0 7.2 6.0 6.6 7.6 6.5 8.9 8.9 7.4 8.5 15.5 7.3 6.3 9.0 5.9 6.4 10.8 11.0 7.2 11.3 6.4 6.3 9.6 7.4 7.1 7.0 9.0 6.3 7.8 10.5 2.3 7.0 6.6 7.5 12.2 9.1 7.0 6.3 11.2 7.9 4.1 6.6 10.9 6.3 7.3 13.5 10.2 9.4 6.7 36.9 32.4 12.5 18.3 17.9 11.9 21.3 14.8 19.8 28.0 27.2 17.8 30.0 24.1 22.7 14.0 33.0 26.9 29.1 28.2 21.0 19.7 22.1 29.4 31.6 18.3 11.5 18.3 26.6 11.8 22.6 39.6 14.2 13.2 22.6 25.3 15.4 15.9 21.2 35.7 24.9 23.8 25.0 17.4 38.6 21.8 20.8 26.4 15.2 18.1 11.6 12.7 28.0 33.4 14.7 28.5 26.4 14.1 13.1 16.6 23.9 33.7 19.6 16.4 22.9 19.9 17.7 30.9 20.1 16.2 11.5 13.1 10.2 14.4 8.6 8.2 9.6 10.2 13.7 8.5 8.5 8.4 4.1 42.0 13.4 7.4 11.6 10.1 6.1 6.3 6.0 6.6 5.9 6.4 6.4 6.3 6.3 6.3 6.6 6.7 6.1 3.2 11.8 1.6 12.7 12.9 12.5 20.1 6.8 3.6 7.2 7.1 5.9 15.7 14.9 11.0 0.0 52.7 7.1 17.9 15.6 31.5 0.3 6.0 5.7 11.5 6.1 31.5 0.8 15.1 35.3 7.6 10.2 9.7 8.8 13.1 10.4 11.4 24.2 6.7 0.7 10.1 10.2 10.9 11.1 1.1 5.9 12.0 0.0 1.9 21.7 5.2 16.5 1.0 1.9 20.5 19.1 8.6 9.8 10.5 16.6 21.6 11.8 2.1 19.7 4.4 6.9 1.4 10.6 13.8 12.6 47.6 11.6 12.4 13.7 13.2 APLNR "AGTRL1, APJ, APJR, FLJ90771" ENSG00000134817 "Apelin receptor" P35414 11 57233577-57237235 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 268.8;lymphoid tissue: 101.0;placenta: 88.1" "Group enriched" "Detected in some" 7 "Adipocytes: 67.6;Endothelial cells: 98.5" "Cancer enhanced" "Detected in all" "glioma: 50.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "AF22: 4.9;HEL: 4.3;K-562: 1.3;NTERA-2: 1.8;SuSa: 2.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025842 Approved NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB025842: " "unprognostic (5.06e-2)" "unprognostic (3.56e-1)" "unprognostic (2.70e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-1)" "unprognostic (6.68e-3)" "unprognostic (1.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (4.72e-1)" "unprognostic (1.77e-3)" "unprognostic (3.27e-2)" "unprognostic (8.13e-2)" "unprognostic (1.13e-1)" "unprognostic (7.13e-3)" 17.3 3.7 47.1 9.4 46.3 0.1 10.6 52.0 45.7 2.3 22.7 5.4 4.5 3.5 0.3 4.1 1.2 13.0 23.7 48.3 130.5 5.7 18.5 8.1 9.6 268.8 97.4 0.7 2.0 2.9 2.4 88.1 92.2 1.0 6.0 0.0 3.5 1.9 15.2 7.1 4.2 9.9 99.9 101.0 3.2 1.4 92.7 4.1 9.5 10.8 4.2 6.2 1.7 122.4 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.1 46.3 52.0 45.7 48.3 130.5 268.8 97.4 92.2 99.9 92.7 122.4 67.6 0.0 0.0 6.5 0.6 2.3 0.1 0.0 0.0 0.0 0.5 0.6 3.2 1.5 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.3 0.3 98.5 0.0 0.0 0.0 0.2 0.1 2.6 0.0 0.5 0.0 0.0 10.4 0.0 0.2 0.0 0.0 0.0 0.0 0.8 2.6 0.2 0.0 0.5 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 2.7 0.0 0.0 0.3 3.1 0.1 0.2 2.7 0.0 0.1 APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 325.4;Hepatocytes: 251.1;Syncytiotrophoblasts: 751.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" 168.0 44.6 59.2 47.2 60.1 187.4 84.6 76.0 65.4 41.8 62.2 46.5 32.7 46.8 106.3 26.7 46.0 43.1 37.5 64.1 72.6 50.5 314.0 53.2 44.0 61.4 62.8 40.8 45.2 83.4 78.7 80.2 68.6 44.2 42.9 32.0 40.1 47.9 39.5 55.8 34.7 49.2 60.5 66.6 38.5 54.2 69.7 42.4 209.1 24.4 34.1 51.8 29.5 68.8 110.6 191.3 90.0 139.5 175.3 97.5 94.4 141.8 153.4 133.3 137.4 113.7 189.3 45.9 161.1 170.6 232.1 198.1 85.0 165.1 149.1 62.3 69.7 51.2 66.0 226.9 140.9 99.5 115.4 134.3 226.9 154.9 107.0 173.8 192.5 73.4 61.5 195.8 128.6 168.1 68.9 108.2 59.3 166.6 172.1 56.3 312.8 96.3 140.2 98.9 150.6 59.4 146.9 240.5 157.1 92.0 87.6 78.8 173.7 156.9 140.6 134.7 209.5 113.0 134.3 50.9 83.1 148.0 151.9 61.8 99.3 198.9 367.9 98.6 228.8 36.4 100.8 268.2 102.1 37.4 78.6 202.2 680.7 343.8 71.3 50.7 75.0 363.3 59.2 60.1 76.0 65.4 64.1 72.6 61.4 62.8 68.6 60.5 69.7 68.8 28.5 19.2 32.7 25.8 22.2 24.3 46.7 77.6 17.1 51.4 48.1 32.1 17.5 34.3 39.7 49.7 10.4 325.4 163.2 18.9 17.6 72.0 22.9 18.0 26.3 42.4 18.0 33.6 24.0 45.4 50.6 40.6 15.3 23.8 36.1 68.6 41.4 251.1 95.9 16.8 25.4 19.4 85.5 50.0 94.8 32.5 65.0 59.5 46.2 42.2 105.1 35.0 222.5 19.6 15.9 40.8 25.4 82.0 54.9 34.1 20.8 13.2 24.5 22.5 39.5 36.9 33.2 97.1 90.1 16.7 20.0 751.1 96.7 38.3 28.0 28.1 APOBR "APOB100R, APOB48R" ENSG00000184730 "Apolipoprotein B receptor" Q0VD83 16 28494643-28498970 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 34.9;intestine: 26.3;lung: 11.6;lymphoid tissue: 36.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 149.9;granulocytes: 39.3;Intestinal goblet cells: 47.5;NK-cells: 65.9;Paneth cells: 84.8;Undifferentiated cells: 49.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 41.6;HMC-1: 124.8;NB-4: 35.7;THP-1: 25.8;U-937: 30.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041667, HPA042093" Enhanced NA NA 700000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041667: AB_10793972, HPA042093: AB_10795393" "unprognostic (3.16e-1)" "unprognostic (8.01e-3)" "unprognostic (6.19e-3)" "prognostic favorable (3.26e-4)" "unprognostic (5.48e-2)" "unprognostic (4.79e-3)" "unprognostic (1.17e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-2)" "unprognostic (7.60e-3)" "unprognostic (7.96e-2)" "unprognostic (1.78e-1)" "unprognostic (1.34e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" "unprognostic (1.07e-1)" "unprognostic (1.25e-2)" 3.3 2.0 0.9 20.0 0.9 34.9 1.6 1.1 2.0 1.3 0.9 26.3 6.1 1.1 1.4 1.6 2.4 2.8 1.3 0.9 1.7 1.1 2.7 11.6 6.7 2.3 1.3 0.4 1.3 0.6 0.7 2.7 1.8 1.8 16.1 0.1 2.1 3.5 1.1 3.1 9.4 2.7 1.5 36.6 4.1 1.3 2.6 3.7 1.2 1.1 3.8 4.8 1.1 2.2 0.1 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.1 0.2 2.2 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 41.6 0.3 0.5 0.0 15.4 124.8 0.0 0.1 0.0 0.0 0.1 0.0 0.4 1.3 0.7 0.0 1.2 1.5 35.7 0.0 0.0 0.0 0.9 0.1 0.0 0.0 1.9 0.0 0.0 0.1 1.1 0.1 0.1 1.4 25.8 0.1 0.0 0.0 0.1 0.0 0.7 0.3 1.5 0.1 30.8 0.1 10.5 5.8 16.5 2.4 2.9 2.3 0.0 1.3 2.4 5.0 0.1 0.3 1.2 17.1 7.3 2.6 0.9 0.4 2.3 0.9 0.9 1.1 2.0 0.9 1.7 2.3 1.3 1.8 1.5 2.6 2.2 0.3 3.2 7.7 0.0 2.2 0.8 0.2 0.1 0.0 0.0 2.2 0.6 0.6 0.0 2.7 3.7 0.0 2.1 21.9 149.9 0.0 0.0 0.1 0.2 0.2 0.7 9.1 6.5 0.0 0.2 14.6 1.0 1.1 0.2 39.3 0.1 0.7 0.6 32.3 0.0 0.0 47.5 0.0 30.1 32.5 0.4 0.3 33.9 1.8 1.9 34.8 0.0 65.9 0.0 0.1 0.0 84.8 0.0 5.7 0.1 6.5 0.1 0.8 0.0 6.6 0.0 0.4 0.4 0.3 0.0 0.3 5.9 16.0 0.0 49.3 0.4 APOC1 ENSG00000130208 "Apolipoprotein C1" P02654 19 44914247-44919349 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "liver: 16232.1" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 33405.9" "Cancer enriched" "Detected in all" 21 "liver cancer: 3253.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 5.6" "Lineage enriched" "Detected in single" 12 "dendritic cells: 5.6" "Cell line enhanced" "Detected in many" "Hep G2: 576.4;HSkMC: 332.9;K-562: 151.6;SK-MEL-30: 268.0" "Low region specificity" "Detected in all" HPA051518 Supported "Secreted to blood" NA NA 20300000000 15000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA051518: AB_2681519" "unprognostic (3.51e-2)" "unprognostic (3.31e-3)" "unprognostic (1.14e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.15e-7)" "unprognostic (9.51e-3)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.52e-1)" "unprognostic (7.13e-3)" "unprognostic (3.48e-3)" "unprognostic (1.65e-1)" "unprognostic (2.01e-3)" "unprognostic (1.65e-1)" 59.2 1998.1 90.3 28.1 133.0 52.2 87.1 83.3 338.1 29.0 73.6 29.1 13.1 11.0 42.0 5.9 21.2 31.0 10.9 75.3 109.8 14.6 16232.1 289.9 140.1 133.2 152.8 56.4 21.4 16.3 23.6 41.7 121.9 14.4 16.7 15.1 35.5 2.2 22.2 73.1 49.1 4.0 92.7 254.9 22.7 18.7 139.2 37.4 36.3 6.1 33.9 23.5 11.3 169.4 2.7 26.5 12.0 5.0 37.1 38.2 111.5 1.3 1.7 4.8 7.3 55.6 49.9 8.4 9.4 1.0 3.2 1.8 15.6 1.9 2.3 0.4 63.5 36.8 4.2 576.4 32.9 27.5 18.1 332.9 2.8 4.8 1.8 9.2 1.3 1.8 151.6 0.8 1.7 3.6 1.5 2.0 112.4 10.4 5.6 6.2 16.0 0.8 7.3 2.0 5.3 3.3 18.9 0.3 268.0 37.7 2.2 98.4 4.2 0.4 1.7 0.2 1.7 4.5 5.4 8.2 0.7 7.4 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.3 90.3 133.0 83.3 338.1 75.3 109.8 133.2 152.8 121.9 92.7 139.2 169.4 22.9 115.4 214.4 2.3 40.6 17.0 4.1 5.8 6.2 2.5 49.8 92.8 0.8 453.2 55.8 1.8 0.0 31.7 1.6 2.4 49.0 4.6 1.2 6.6 128.4 68.9 2.4 768.8 0.3 4.0 341.3 93.0 19.4 5.0 142.6 30.6 432.6 33405.9 4789.8 0.0 0.5 3.2 4.1 867.7 27.3 22.8 270.9 620.5 30.2 3.7 124.5 276.0 0.0 0.0 0.0 3.2 0.3 259.5 1.3 4.2 0.6 16.6 24.4 9.9 19.7 1628.8 24.4 2.0 3.2 3.7 17.8 71.6 46.7 1226.7 2.1 5.0 APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Approved Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA003187: AB_1079375" "unprognostic (2.53e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.86e-2)" "unprognostic (6.38e-3)" "unprognostic (3.45e-1)" "unprognostic (2.42e-1)" "unprognostic (6.18e-2)" "unprognostic (2.95e-1)" "unprognostic (6.45e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "prognostic favorable (2.56e-6)" "unprognostic (2.53e-2)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (5.88e-3)" 9.0 23.7 55.8 9.0 58.0 7.9 13.3 58.1 76.3 13.1 67.8 17.3 14.4 10.6 19.6 12.6 20.8 9.3 65.1 57.9 58.4 46.5 18.2 8.6 11.7 58.8 57.0 9.4 14.2 62.0 29.2 10.9 57.3 13.7 18.8 52.8 19.7 15.0 45.9 7.7 12.0 12.0 57.0 8.4 17.7 16.8 56.8 14.0 20.3 73.2 11.6 11.2 8.1 57.1 36.5 32.7 53.9 37.8 8.8 19.9 8.3 17.9 21.9 37.4 38.8 19.3 17.0 31.5 21.9 16.5 48.5 29.3 68.5 35.7 41.2 33.4 48.7 15.9 28.6 31.1 20.8 40.9 17.1 22.2 20.7 41.2 30.4 20.1 26.6 38.8 22.9 33.2 35.1 34.6 41.2 43.0 49.2 47.5 52.7 31.5 26.6 75.6 74.1 18.4 36.4 26.5 39.0 36.7 39.7 52.4 63.6 17.9 6.5 23.9 14.6 86.6 27.9 26.3 50.5 28.7 38.5 19.8 35.8 14.8 4.8 1.4 12.6 15.9 16.6 10.8 13.7 12.5 14.0 10.2 10.9 10.7 3.0 10.3 16.0 16.6 14.0 7.7 55.8 58.0 58.1 76.3 57.9 58.4 58.8 57.0 57.3 57.0 56.8 57.1 7.4 16.0 11.5 61.7 11.8 14.0 17.0 74.3 11.4 20.4 14.3 17.0 61.8 21.5 28.3 23.9 14.6 17.2 11.3 12.8 180.0 28.4 25.9 56.0 13.0 10.1 7.2 20.8 61.4 16.0 8.9 11.7 13.3 24.4 3.8 14.2 7.9 13.9 22.7 20.2 76.5 17.0 44.7 14.6 12.0 15.7 11.5 9.9 28.4 74.0 34.2 50.0 8.2 43.7 76.5 10.2 20.0 15.8 14.8 14.1 24.0 80.6 106.9 32.4 6.6 10.8 22.3 26.1 53.2 18.9 7.0 12.4 9.5 17.0 22.3 16.8 AQP2 ENSG00000167580 "Aquaporin 2" P41181 12 49950737-49958878 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 92 "kidney: 386.9;seminal vesicle: 212.4" "Cell type enriched" "Detected in some" 440 "Collecting duct cells: 4143.6" "Group enriched" "Detected in some" 6 "renal cancer: 1.7;stomach cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.4;HEL: 1.1;HMC-1: 2.2;OE19: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA046834 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA046834: AB_2679830" "unprognostic (2.10e-1)" "unprognostic (3.77e-2)" "unprognostic (6.96e-3)" "unprognostic (4.48e-3)" "unprognostic (3.60e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (7.38e-3)" "unprognostic (5.92e-2)" "unprognostic (4.60e-2)" "unprognostic (2.01e-2)" "unprognostic (1.11e-1)" 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.0 0.0 0.2 1.5 0.0 0.0 386.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 212.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 3.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 4143.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 9.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.1 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1526.1;skin 1: 581.9;urinary bladder: 688.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1923.3;Basal prostatic cells: 982.0;Collecting duct cells: 1609.3;Prostatic glandular cells: 1430.8;Squamous epithelial cells: 2189.3;Suprabasal keratinocytes: 2485.4;Urothelial cells: 2455.4" "Group enriched" "Detected in all" 5 "cervical cancer: 319.0;head and neck cancer: 283.7;lung cancer: 146.8;urothelial cancer: 221.3" "Group enriched" "Detected in many" 4 "hippocampal formation: 5.3;medulla oblongata: 16.0;pons: 21.0" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 181.7;T-reg: 205.4" "Lineage enriched" "Detected in many" 18 "T-cells: 205.4" "Cell line enhanced" "Detected in many" "HaCaT: 127.1;HeLa: 213.2;JURKAT: 130.7;RT4: 216.6;SK-BR-3: 149.7;U-266/70: 151.2;U-266/84: 213.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA014924: AB_2669120" "unprognostic (4.29e-2)" "prognostic favorable (5.31e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-2)" "unprognostic (1.11e-2)" "unprognostic (9.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.46e-1)" "unprognostic (9.06e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (4.51e-2)" 10.9 2.1 1.5 16.8 0.4 19.7 36.6 2.4 3.4 173.3 1.4 10.3 73.4 10.9 2.9 1526.1 25.4 9.4 31.5 5.3 0.4 131.7 118.6 114.0 16.1 16.0 1.6 12.1 43.1 2.0 2.8 6.0 21.0 85.6 10.1 1.7 399.7 36.8 5.3 581.9 100.5 3.2 0.2 110.1 35.9 2.8 0.8 233.9 2.3 26.7 172.5 688.6 529.9 0.9 0.6 38.6 1.9 0.0 67.7 12.2 1.0 0.3 0.9 0.9 1.1 20.5 12.0 0.5 9.1 0.0 0.5 127.1 6.2 0.7 0.2 61.6 6.0 4.3 213.2 1.9 0.4 1.3 1.3 1.9 6.5 0.5 0.2 0.2 0.5 130.7 67.4 58.8 6.9 29.1 60.4 23.0 5.3 88.6 0.7 0.9 94.3 10.8 1.3 216.6 1.7 4.7 32.3 149.7 0.1 8.0 0.9 10.6 1.2 0.0 1.0 0.4 0.4 151.2 213.6 14.5 0.5 0.4 0.2 1.6 0.5 0.1 20.2 0.4 181.7 11.3 171.9 52.8 0.3 3.0 97.3 47.1 2.3 3.0 0.5 11.1 205.4 43.0 1.5 0.4 2.4 3.4 5.3 0.4 16.0 1.6 21.0 0.2 0.8 0.9 9.2 38.5 249.9 0.0 42.4 1923.3 982.0 381.4 811.0 9.7 56.8 27.8 3.4 157.3 436.3 1609.3 2.1 0.9 21.6 2.7 0.0 37.4 2.2 82.3 21.4 37.1 8.3 71.4 0.3 48.9 2.0 27.5 16.3 96.2 20.8 0.2 16.4 137.3 2.2 0.0 0.1 104.0 315.3 3.5 122.9 0.6 33.2 15.3 158.3 0.0 1.6 0.4 4.1 0.5 0.2 28.5 8.1 1.2 246.9 1430.8 343.1 31.9 546.0 0.5 0.0 10.2 35.8 0.7 1.9 2189.3 2485.4 50.2 73.4 1.6 7.3 2455.4 AQP4 MIWC ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 440.5;lung: 114.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1102.6;Alveolar cells type 2: 342.3;Astrocytes: 487.7;Muller glia cells: 227.2" "Cancer enriched" "Detected in some" 22 "glioma: 223.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.4;RPTEC TERT1: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions" "CAB005079: AB_2274338, CAB058689: AB_2665579, HPA014784: AB_1844967" "unprognostic (7.23e-5)" "unprognostic (1.55e-1)" "unprognostic (3.19e-8)" "unprognostic (3.68e-1)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.34e-1)" "unprognostic (5.38e-3)" "unprognostic (1.64e-3)" "unprognostic (8.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.10e-2)" 0.1 0.1 272.7 0.0 298.7 0.0 0.3 282.0 246.3 0.6 62.9 0.3 0.0 0.0 0.8 0.9 1.1 0.1 2.8 283.6 440.5 2.3 0.9 114.8 0.3 250.5 351.2 2.5 0.2 2.2 3.7 0.0 333.3 0.4 0.0 60.2 0.7 0.2 60.1 0.1 0.1 0.0 333.0 0.5 11.4 0.5 387.1 0.2 14.7 20.9 0.1 0.1 0.1 376.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.7 298.7 282.0 246.3 283.6 440.5 250.5 351.2 333.3 333.0 387.1 376.0 0.0 1102.6 342.3 487.7 0.0 0.0 0.8 0.6 0.0 3.1 0.8 0.9 13.9 4.3 76.6 3.7 6.2 0.0 0.0 0.1 3.9 0.3 0.0 0.7 0.1 1.8 0.0 0.0 3.0 0.0 0.0 0.8 0.0 0.0 3.8 0.0 0.0 0.5 0.0 1.7 1.1 0.0 0.0 0.0 0.3 0.0 5.0 0.8 0.0 9.4 0.0 227.2 0.0 12.1 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.1 9.1 0.0 4.3 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 2.0 AQP5 ENSG00000161798 "Aquaporin 5" P55064 12 49961872-49965682 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 622.6;testis: 222.0" "Group enriched" "Detected in many" 7 "Early spermatids: 1542.9;Late spermatids: 4265.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 87.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "OE19: 223.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065008 Enhanced Approved "Plasma membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA065008: AB_2685401" "unprognostic (4.67e-3)" "unprognostic (5.00e-2)" "unprognostic (3.30e-1)" "unprognostic (6.00e-3)" "unprognostic (1.92e-3)" "prognostic favorable (1.75e-5)" "unprognostic (4.13e-3)" "unprognostic (1.02e-2)" "unprognostic (9.39e-2)" "unprognostic (3.70e-3)" "unprognostic (2.88e-3)" "unprognostic (2.46e-3)" "unprognostic (1.69e-4)" "unprognostic (2.53e-1)" "unprognostic (5.28e-2)" "unprognostic (2.51e-3)" "unprognostic (9.11e-3)" 2.9 0.8 2.7 0.1 3.7 0.2 17.1 3.3 2.7 12.9 1.5 0.4 15.3 2.7 0.2 16.5 0.7 2.8 4.0 2.4 2.9 1.9 0.1 7.6 0.0 3.3 3.9 0.2 2.0 3.0 1.2 0.0 3.1 1.3 0.0 1.0 622.6 1.0 0.2 112.7 0.1 0.3 2.6 0.4 52.3 222.0 3.8 0.0 1.6 0.0 0.1 0.3 0.4 2.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.7 223.2 0.0 10.1 0.0 0.0 0.3 0.0 0.2 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.7 3.3 2.7 2.4 2.9 3.3 3.9 3.1 2.6 3.8 2.6 0.5 57.7 3.1 0.0 0.1 1.3 0.5 18.3 0.0 0.8 53.9 48.0 0.3 0.0 56.4 7.3 0.0 0.0 0.1 0.0 0.0 0.1 1542.9 1.5 0.1 1.8 0.0 0.0 0.0 0.2 0.0 1.4 34.7 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 26.4 0.0 1.6 4265.6 28.6 1.7 295.3 0.0 0.0 53.7 0.0 3.0 0.1 7.2 0.0 19.2 0.3 1.6 0.0 0.0 9.7 1.7 19.7 0.0 1.8 403.9 15.9 1.3 0.9 0.0 0.6 18.7 0.0 0.6 AQP6 AQP2L ENSG00000086159 "Aquaporin 6" Q13520 12 49967194-49977139 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 52.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.2;Cardiomyocytes: 8.3;Collecting duct cells: 5.5;Ionocytes: 2.0" "Cancer enriched" "Detected in many" 9 "renal cancer: 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.4" "Region enriched" "Detected in some" 7 "cerebellum: 21.0" "Not detected" "Not detected" HPA015278 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA015278: AB_10600982" "unprognostic (1.23e-1)" "unprognostic (1.32e-2)" "unprognostic (9.53e-2)" "unprognostic (2.02e-2)" "unprognostic (6.46e-2)" "unprognostic (4.60e-3)" "unprognostic (3.45e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.74e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.03e-2)" "unprognostic (1.77e-1)" 0.1 0.2 2.8 0.1 4.1 0.0 0.1 5.6 2.6 0.3 1.6 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.2 2.7 2.5 52.7 0.3 0.1 0.0 4.9 4.6 0.0 0.1 0.2 0.2 0.0 5.2 0.2 0.0 0.2 1.0 0.2 0.0 0.3 0.2 0.1 3.4 0.0 0.4 2.4 6.1 0.0 0.0 0.0 0.0 0.1 0.1 3.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 1.4 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.1 5.6 2.6 2.7 2.5 4.9 4.6 5.2 3.4 6.1 3.3 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.6 0.0 0.1 0.4 0.3 8.3 0.0 0.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 1.6 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.2 0.6 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 AQP9 "HsT17287, SSC1" ENSG00000103569 "Aquaporin 9" O43315 15 58138169-58185911 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 702.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 313.9;Macrophages: 82.1" "Cancer enriched" "Detected in many" 30 "liver cancer: 132.4" "Region enhanced" "Detected in many" "cerebral cortex: 14.4" "Immune cell enriched" "Detected in many" 20 "neutrophil: 1161.4" "Lineage enriched" "Detected in many" 20 "granulocytes: 1161.4" "Cell line enriched" "Detected in some" 29 "U-87 MG: 29.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA074762, CAB075684" Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "CAB075684: , HPA074762: AB_2732267" "unprognostic (1.91e-1)" "unprognostic (1.92e-1)" "unprognostic (7.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.24e-2)" "unprognostic (4.15e-2)" "unprognostic (1.36e-3)" "unprognostic (2.28e-2)" "unprognostic (3.82e-2)" "unprognostic (2.03e-1)" "unprognostic (4.80e-3)" "unprognostic (6.98e-2)" "prognostic unfavorable (5.72e-11)" "unprognostic (8.78e-2)" "unprognostic (1.13e-2)" "unprognostic (1.25e-1)" "unprognostic (8.39e-2)" 18.2 0.8 0.8 72.9 0.9 67.5 2.4 0.9 14.4 1.3 0.8 0.9 0.2 1.2 43.4 1.2 7.1 5.3 1.7 3.2 0.5 0.9 702.7 22.2 0.6 0.7 1.0 0.5 1.6 5.6 0.3 6.2 4.0 0.9 0.3 0.4 1.1 0.7 0.5 22.0 0.9 6.4 0.6 42.7 1.5 0.3 6.9 1.8 0.6 7.5 0.8 32.6 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 29.7 0.1 0.0 0.2 58.4 1.2 0.1 17.5 0.1 0.5 0.1 0.0 1.8 0.1 0.1 0.0 1161.4 0.3 23.0 0.6 0.3 18.9 0.8 0.9 0.9 14.4 3.2 0.5 0.7 1.0 4.0 0.6 6.9 0.8 0.7 0.0 12.2 0.3 2.3 0.4 0.2 0.0 0.0 0.0 0.1 0.0 1.1 5.7 3.1 0.0 0.0 0.3 0.5 0.0 0.0 0.1 2.1 0.3 0.1 0.7 0.0 13.9 2.4 0.2 0.9 1.9 0.0 1.8 7.6 0.0 7.9 313.9 40.8 0.0 0.8 0.0 0.0 28.5 6.2 1.9 0.3 82.1 0.0 0.0 18.9 0.0 1.0 0.5 0.2 0.5 0.0 0.0 0.7 0.2 0.0 0.3 1.5 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.8 1.5 0.0 0.0 0.1 ARAP2 "CENTD1, PARX" ENSG00000047365 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2" Q8WZ64 4 35948221-36244514 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.9;brain: 92.8" "Cell type enhanced" "Detected in many" "Astrocytes: 285.4;Late spermatids: 167.5;Oligodendrocytes: 781.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.7;hTCEpi: 12.7;MOLT-4: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035925 Approved Approved "Actin filaments,Focal adhesion sites" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Actin filaments" "HPA035925: AB_10672075" "unprognostic (2.97e-2)" "unprognostic (8.62e-2)" "unprognostic (3.43e-3)" "unprognostic (1.04e-1)" "unprognostic (8.86e-2)" "unprognostic (2.72e-3)" "unprognostic (1.09e-1)" "unprognostic (3.78e-3)" "unprognostic (2.04e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-3)" "unprognostic (2.96e-1)" "unprognostic (4.48e-2)" "unprognostic (4.54e-2)" "unprognostic (3.43e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-2)" 4.5 2.2 28.9 10.0 70.4 39.9 5.1 19.9 39.5 3.5 0.0 5.3 8.9 3.3 3.8 13.1 3.3 9.3 1.5 24.5 21.5 3.7 9.4 13.4 15.7 34.1 38.8 1.5 7.0 5.4 2.9 3.5 32.6 2.2 5.6 1.4 4.6 2.9 0.7 16.1 8.9 4.3 18.3 11.5 6.1 6.2 32.1 24.6 23.2 0.8 11.0 9.9 6.3 92.8 8.6 0.7 0.8 0.3 0.0 0.0 4.2 0.0 0.0 0.0 0.0 4.2 13.7 4.1 3.2 0.4 0.0 3.2 1.3 6.7 0.0 0.0 7.6 0.1 2.9 0.2 1.6 5.5 0.0 0.4 12.7 0.0 2.7 4.9 0.0 11.1 0.2 0.7 0.0 3.6 12.8 4.5 1.0 6.0 2.6 6.5 0.0 4.7 9.3 8.7 7.3 0.0 0.4 2.1 2.7 0.4 5.6 1.6 0.0 2.3 7.5 0.0 1.1 0.0 0.0 8.0 0.9 6.1 1.9 0.0 0.5 0.0 3.8 1.8 3.5 1.8 2.1 2.7 0.3 0.9 0.7 1.9 0.4 6.7 4.7 1.2 1.1 0.6 28.9 70.4 19.9 39.5 24.5 21.5 34.1 38.8 32.6 18.3 32.1 92.8 18.6 153.8 23.3 285.4 46.1 39.1 32.9 13.5 21.6 0.8 11.2 7.0 2.1 17.2 33.2 7.3 0.0 0.2 100.4 15.5 7.9 7.9 123.6 31.4 3.0 15.8 3.0 8.6 140.8 10.0 0.4 9.4 20.4 50.0 9.5 5.9 3.3 4.2 8.7 0.0 29.9 11.3 6.1 33.2 24.9 167.5 2.8 35.1 5.4 40.3 26.7 5.4 95.8 161.4 781.2 21.5 23.3 0.7 43.0 30.0 17.4 5.8 18.0 1.2 0.0 8.1 3.6 4.2 3.0 37.0 67.5 0.8 90.7 0.1 6.9 44.1 ARAP3 "CENTD3, DRAG1, FLJ21065" ENSG00000120318 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" Q8WWN8 5 141653401-141682230 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 33.2;Endothelial cells: 28.3;Hepatic stellate cells: 28.5;Horizontal cells: 38.7;Microglial cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.3;neutrophil: 2.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 39.4;HUVEC TERT2: 74.3;TIME: 53.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042887 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042887: AB_10796681" "unprognostic (1.98e-1)" "unprognostic (4.88e-2)" "unprognostic (9.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.58e-2)" "unprognostic (5.26e-2)" "unprognostic (3.77e-3)" "unprognostic (9.76e-2)" "unprognostic (3.43e-2)" "unprognostic (1.39e-1)" "unprognostic (4.42e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (4.96e-2)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" 11.4 4.1 4.6 5.4 4.7 6.2 10.1 5.2 5.4 9.5 1.5 4.5 3.2 7.5 5.4 3.2 7.8 6.7 14.1 3.3 2.9 7.8 2.1 15.8 2.3 4.1 4.4 3.7 2.5 5.3 5.1 11.9 4.4 7.4 2.6 3.9 3.9 5.8 7.0 2.6 4.6 5.9 3.1 7.3 4.3 1.6 6.3 0.7 8.5 9.2 1.2 7.8 7.3 2.9 11.9 7.5 29.4 0.0 1.8 4.5 0.3 7.0 7.9 7.2 9.2 4.7 0.9 0.1 39.4 2.6 11.7 12.8 5.0 16.8 5.5 0.2 2.1 11.0 12.6 0.1 8.2 0.9 0.4 8.3 7.6 3.9 8.9 20.1 74.3 0.0 0.8 0.1 1.0 0.3 0.0 9.5 17.4 3.9 9.4 0.2 2.3 0.0 0.8 5.4 0.5 24.7 15.1 0.8 12.7 10.6 0.4 2.8 53.3 4.8 10.8 1.3 14.7 0.0 0.1 0.1 12.4 12.6 24.3 0.3 0.5 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.1 0.2 4.6 4.7 5.2 5.4 3.3 2.9 4.1 4.4 4.4 3.1 6.3 2.9 33.2 3.2 8.6 0.3 0.3 0.5 1.7 3.1 0.0 6.1 0.9 2.2 5.2 0.0 2.6 1.8 0.0 0.1 1.6 1.3 0.0 1.2 0.0 0.7 2.3 28.3 0.0 0.0 2.4 0.7 0.1 2.2 1.1 1.2 1.3 0.0 28.5 0.3 1.3 38.7 3.2 1.3 2.0 4.4 2.1 0.6 0.3 2.2 0.0 15.0 2.7 3.6 2.1 1.5 0.1 4.6 1.8 1.5 1.6 2.8 0.0 0.1 0.9 0.9 0.0 1.2 3.3 0.5 0.9 0.8 0.4 0.1 1.5 0.4 2.7 3.6 ARF5 ENSG00000004059 "ADP ribosylation factor 5" P84085 7 127588386-127591700 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 3900000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (6.72e-3)" "unprognostic (2.34e-2)" "unprognostic (1.67e-2)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (5.81e-3)" "unprognostic (9.41e-2)" "unprognostic (2.69e-1)" "unprognostic (2.75e-2)" "unprognostic (7.02e-2)" "unprognostic (1.02e-1)" "unprognostic (9.69e-2)" "unprognostic (1.50e-1)" "unprognostic (1.26e-2)" "unprognostic (3.95e-1)" "unprognostic (2.46e-2)" 100.2 93.7 139.3 72.6 147.7 143.0 99.8 128.4 200.6 100.7 124.4 108.3 92.3 104.8 114.1 227.5 97.5 81.7 118.6 152.0 137.2 125.8 139.0 90.8 102.7 133.8 132.0 72.1 168.1 104.0 100.2 69.3 135.1 98.7 61.3 22.9 103.1 71.1 131.9 199.8 98.5 66.3 131.9 105.8 117.8 82.9 135.2 95.8 80.5 101.4 74.6 92.5 122.1 133.4 157.4 148.9 120.1 386.5 101.6 159.1 163.3 43.9 129.6 118.7 135.8 232.0 211.4 114.7 64.4 132.6 135.9 117.5 92.4 198.0 38.4 104.9 222.8 44.9 137.5 160.2 150.1 69.7 100.1 163.1 196.2 77.7 75.8 94.5 173.2 164.1 105.1 124.1 116.9 531.2 249.0 303.7 179.9 157.1 191.7 148.3 73.9 245.6 198.2 158.7 349.1 226.2 142.8 461.8 116.1 77.6 123.9 108.0 103.7 177.3 75.3 128.0 101.9 115.2 77.5 153.9 181.1 142.0 154.6 289.0 321.4 279.7 144.3 270.3 146.7 129.5 151.1 148.4 409.6 117.2 112.0 122.2 447.5 156.5 216.2 259.6 181.8 381.8 139.3 147.7 128.4 200.6 152.0 137.2 133.8 132.0 135.1 131.9 135.2 133.4 110.3 3.2 12.1 28.4 81.3 105.7 72.9 217.1 130.9 14.8 111.8 180.7 2.0 91.5 83.0 112.2 0.0 151.6 89.7 89.4 201.5 107.8 39.3 90.3 95.7 73.9 119.9 102.2 46.5 90.7 125.0 82.2 135.5 88.2 21.0 91.1 75.7 51.6 102.7 20.2 42.5 108.8 140.4 129.6 221.9 40.7 93.2 123.9 149.4 28.1 118.6 27.6 82.4 27.2 36.2 86.4 134.0 94.8 75.1 57.2 147.5 160.0 58.4 11.9 72.3 58.7 85.4 99.2 116.7 248.3 153.4 146.3 100.2 69.1 125.4 93.4 ARF6 ENSG00000165527 "ADP ribosylation factor 6" P62330 14 49893082-49897054 "Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 716.1;Suprabasal keratinocytes: 673.3;Urothelial cells: 703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002778, CAB079914" Approved Supported Cytosol NA NA 310000 "Cluster 44: Non-specific - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB002778: , CAB079914: AB_2539861" "unprognostic (1.21e-1)" "unprognostic (2.75e-3)" "unprognostic (1.80e-1)" "unprognostic (7.02e-2)" "unprognostic (2.85e-1)" "unprognostic (1.83e-1)" "unprognostic (4.12e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.10e-5)" "unprognostic (1.61e-1)" "unprognostic (1.67e-1)" "unprognostic (8.37e-3)" "unprognostic (1.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.49e-2)" 32.1 25.3 13.4 43.6 14.2 83.1 32.6 15.2 15.3 35.7 16.3 53.4 46.4 21.7 26.6 108.2 28.3 32.8 18.3 11.8 14.3 29.7 46.1 31.5 62.0 14.7 14.3 15.3 24.7 20.4 12.6 36.3 15.4 32.2 51.0 13.2 36.3 19.2 26.1 66.0 51.2 23.8 15.6 49.6 46.7 15.8 15.9 45.2 21.1 17.1 66.7 46.8 55.7 15.6 141.5 58.2 38.4 44.8 51.5 68.4 78.3 86.5 62.6 60.3 62.2 42.6 96.2 91.3 43.7 72.7 46.3 101.7 43.7 69.3 71.3 181.4 34.9 47.2 30.6 38.3 58.1 87.2 60.7 53.7 81.5 48.9 93.7 72.1 67.6 58.3 45.9 176.9 84.7 101.5 77.7 76.5 42.0 75.9 82.8 59.4 50.1 53.9 157.6 112.9 56.4 37.4 68.9 102.3 89.0 46.5 78.0 70.0 90.0 111.9 57.4 66.7 66.1 94.3 104.4 68.6 40.1 50.9 81.3 34.2 20.7 21.1 34.7 33.0 37.6 33.5 33.7 35.3 23.9 26.6 23.0 29.6 14.7 29.1 31.4 15.8 36.2 23.4 13.4 14.2 15.2 15.3 11.8 14.3 14.7 14.3 15.4 15.6 15.9 15.6 102.9 51.3 29.9 2.9 233.7 599.8 529.1 47.9 231.6 22.9 154.4 80.1 18.5 127.2 47.6 101.2 2.1 152.7 298.8 276.0 158.5 125.4 5.8 95.6 98.5 117.1 99.3 140.1 5.3 80.0 208.1 94.9 115.7 143.7 79.9 40.3 108.5 143.3 168.0 33.7 5.9 167.0 20.3 195.6 716.1 8.3 33.5 184.5 304.1 15.0 204.9 42.2 192.6 6.0 8.9 130.4 161.6 32.7 182.4 443.4 190.8 166.5 30.3 21.6 46.0 68.8 90.7 62.7 48.7 361.4 673.3 202.9 311.0 52.6 182.5 703.8 ARFGAP2 "FLJ14576, IRZ, Zfp289, ZNF289" ENSG00000149182 "ADP ribosylation factor GTPase activating protein 2" Q8N6H7 11 47164299-47177125 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016649, HPA018152" Enhanced Supported "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "HPA016649: AB_1844980, HPA018152: AB_1844979" "unprognostic (1.69e-2)" "unprognostic (9.11e-2)" "unprognostic (5.91e-2)" "unprognostic (3.75e-2)" "unprognostic (2.20e-2)" "unprognostic (1.12e-1)" "unprognostic (4.81e-3)" "unprognostic (1.23e-1)" "unprognostic (1.25e-1)" "unprognostic (2.41e-1)" "unprognostic (3.42e-2)" "unprognostic (7.00e-2)" "prognostic favorable (7.65e-7)" "unprognostic (2.05e-1)" "unprognostic (9.36e-2)" "unprognostic (1.06e-1)" "unprognostic (9.20e-2)" 38.0 51.4 62.1 36.3 63.9 82.2 41.7 63.2 68.3 42.3 57.2 49.4 40.0 43.3 35.5 60.8 49.3 32.1 58.7 62.5 60.1 47.6 76.8 40.7 51.9 65.1 61.8 44.6 69.7 48.2 38.7 39.9 61.8 51.4 39.4 38.9 56.1 41.7 115.9 78.7 43.8 38.8 60.6 51.2 55.7 30.7 63.1 49.8 47.4 81.4 50.5 44.7 43.3 70.3 55.7 36.4 54.9 43.3 45.9 37.3 51.6 51.2 48.1 64.1 48.4 41.3 45.3 91.3 32.4 58.7 40.8 82.3 47.2 74.6 40.3 45.0 46.1 77.6 85.5 50.8 53.7 107.0 84.4 56.7 82.3 33.3 71.1 46.1 60.4 65.6 111.8 67.8 58.5 102.5 50.8 87.8 43.6 98.3 48.4 78.8 94.8 116.8 60.3 79.3 53.0 47.0 58.7 81.7 38.8 26.1 126.8 78.8 48.7 55.2 43.3 50.5 68.6 58.6 60.7 78.3 38.6 81.2 56.4 108.5 69.1 92.8 74.0 77.3 66.6 59.0 57.1 66.2 65.9 63.1 63.0 63.4 41.8 69.2 98.4 35.4 71.8 108.1 62.1 63.9 63.2 68.3 62.5 60.1 65.1 61.8 61.8 60.6 63.1 70.3 23.8 35.3 45.9 25.1 46.5 22.2 31.4 22.1 29.6 73.6 30.9 25.8 13.0 20.0 41.2 31.3 114.7 64.3 40.7 38.6 25.4 38.7 2.7 20.3 26.4 29.8 45.4 47.1 16.2 36.6 47.1 29.7 34.1 27.0 60.8 44.9 31.1 44.0 36.8 74.0 15.1 35.0 38.7 33.6 25.4 6.6 34.2 28.6 28.4 15.9 58.1 51.1 71.1 13.0 23.7 39.2 45.0 26.4 31.7 26.4 41.0 26.3 34.1 115.4 39.5 33.0 28.0 24.7 35.9 30.3 26.7 91.8 43.7 40.3 36.3 34.0 ARFGEF3 "BIG3, C6orf92, dJ171N11.1, KIAA1244, PPP1R33" ENSG00000112379 "ARFGEF family member 3" Q5TH69 6 138161939-138344663 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.4;salivary gland: 18.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 114.6;Excitatory neurons: 200.9;Inhibitory neurons: 207.8;Oligodendrocyte precursor cells: 173.9;Oligodendrocytes: 378.1" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 14.8;RH-30: 13.4;RT4: 19.4;SK-BR-3: 22.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036350 Uncertain NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA036350: AB_10672084" "prognostic unfavorable (8.20e-4)" "unprognostic (4.31e-2)" "unprognostic (9.91e-3)" "unprognostic (5.91e-2)" "unprognostic (2.20e-2)" "unprognostic (4.53e-2)" "unprognostic (4.30e-3)" "unprognostic (1.21e-2)" "unprognostic (7.41e-2)" "unprognostic (7.82e-2)" "unprognostic (3.46e-2)" "unprognostic (4.93e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-1)" "unprognostic (2.38e-1)" "unprognostic (8.87e-2)" "unprognostic (1.69e-2)" 1.2 3.8 13.4 0.7 16.4 0.4 7.9 20.1 17.7 5.0 0.0 4.2 2.2 0.7 0.9 0.4 2.2 1.7 1.0 16.7 13.0 2.1 0.1 6.4 0.2 11.1 17.7 0.1 8.7 15.8 7.0 1.4 14.4 12.0 4.8 2.8 18.0 1.0 0.2 1.2 1.9 0.7 7.5 0.4 10.0 0.6 15.2 0.1 1.9 0.7 0.2 3.4 0.4 28.4 8.0 3.1 0.0 0.6 0.0 0.0 4.7 0.3 0.2 0.2 0.0 0.1 0.4 0.0 3.1 0.3 2.7 2.6 3.8 2.0 0.0 0.0 4.9 0.0 1.5 0.9 0.0 3.0 0.0 0.0 0.9 0.0 0.9 3.5 4.1 2.7 0.0 4.9 0.0 14.8 0.0 0.0 2.7 8.5 3.4 0.6 13.4 2.6 2.6 19.4 6.9 0.0 7.8 22.2 0.9 0.3 4.4 0.0 0.4 0.2 2.2 0.0 7.9 1.7 6.7 0.0 3.2 1.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.4 20.1 17.7 16.7 13.0 11.1 17.7 14.4 7.5 15.2 28.4 9.4 16.0 114.6 34.3 0.5 0.0 18.8 0.0 6.2 19.0 39.9 12.6 6.4 14.3 44.6 3.7 0.0 16.5 0.8 2.5 3.9 11.4 83.0 8.6 1.4 11.9 66.7 2.7 200.9 24.7 2.4 4.1 41.3 17.7 2.5 0.1 8.2 0.3 1.4 11.8 207.8 44.2 0.0 0.0 0.0 22.0 0.0 0.5 0.0 36.5 2.0 0.9 0.0 173.9 378.1 14.2 8.4 0.0 0.9 67.6 2.5 0.3 37.2 3.3 0.0 3.5 0.9 4.1 1.1 3.0 0.0 6.2 0.8 0.1 13.2 42.7 ARG1 ENSG00000118520 "Arginase 1" P05089 6 131470832-131584332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 1203.5" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 991.4" "Cancer enriched" "Detected in some" 45 "liver cancer: 167.7" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "neutrophil: 44.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 44.9" "Cell line enhanced" "Detected in single" "HL-60: 1.4" "Region enhanced" "Detected in single" "cerebellum: 2.4" "Low region specificity" "Detected in all" "HPA003595, CAB009434, HPA024006, CAB056159, CAB080011" Enhanced NA NA 9500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB009434: AB_2058955, CAB056159: AB_2665582, CAB080011: , HPA003595: AB_1078190, HPA024006: AB_1844987" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-1)" "unprognostic (9.95e-2)" "unprognostic (7.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (7.55e-3)" "unprognostic (8.35e-2)" "unprognostic (1.25e-2)" "unprognostic (2.90e-2)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (1.79e-2)" 2.2 0.2 0.1 0.3 0.2 292.0 4.8 1.0 0.5 0.3 0.2 0.2 0.0 0.1 0.0 2.1 1.9 0.0 0.8 0.3 0.2 0.3 1203.5 6.5 0.3 0.4 0.2 0.2 0.4 0.0 0.2 1.7 0.3 0.3 0.0 0.3 0.9 0.0 0.5 92.8 0.3 0.2 0.1 20.6 0.4 0.1 0.2 1.2 0.5 0.6 0.7 0.2 2.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.0 0.1 0.0 0.2 0.7 0.3 44.9 0.0 0.9 0.2 9.3 0.4 0.1 0.2 1.0 0.5 0.3 0.2 0.4 0.2 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.1 1.5 0.0 43.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.2 991.4 0.0 0.0 0.1 0.1 0.0 27.6 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 ARHGAP11A KIAA0013 ENSG00000198826 "Rho GTPase activating protein 11A" Q6P4F7 15 32615144-32639941 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.2;lymphoid tissue: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 38.7;Extravillous trophoblasts: 23.7;Granulosa cells: 21.1;Plasma cells: 18.6;Spermatocytes: 24.7;Spermatogonia: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040830, HPA066481" Enhanced Approved Nucleoli,Cytosol No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "HPA040830: AB_10805830, HPA066481: " "unprognostic (5.00e-2)" "unprognostic (5.57e-2)" "unprognostic (6.10e-2)" "unprognostic (1.97e-1)" "unprognostic (2.93e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.05e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (4.87e-2)" "unprognostic (7.71e-2)" "prognostic unfavorable (2.92e-5)" "unprognostic (3.43e-2)" "unprognostic (1.07e-12)" "unprognostic (7.37e-2)" "unprognostic (5.23e-1)" "unprognostic (1.54e-2)" "unprognostic (9.64e-2)" 1.7 0.9 2.0 7.9 2.5 24.2 1.7 2.1 2.1 1.5 1.2 7.5 6.1 1.5 1.0 5.3 0.8 1.7 0.7 1.7 1.9 0.6 1.3 1.7 13.5 2.6 3.0 0.6 2.6 1.2 0.7 4.3 2.6 0.6 8.8 0.5 1.2 0.5 0.9 4.4 7.6 4.8 2.5 2.8 3.6 8.6 2.2 26.1 1.3 0.4 14.3 2.8 1.9 3.0 80.8 69.4 73.1 46.2 5.0 13.0 39.6 78.5 50.2 80.0 63.3 52.2 41.5 43.5 23.7 49.9 91.3 56.9 55.3 43.8 110.9 83.5 27.4 132.6 68.9 33.5 2.0 103.8 55.5 4.3 5.5 61.6 50.9 15.2 61.5 94.4 101.0 112.7 95.3 31.7 58.6 39.7 44.6 71.6 44.5 67.8 141.7 38.2 28.4 41.6 64.7 44.5 72.9 46.2 17.6 37.6 63.6 115.8 35.3 102.5 74.1 42.0 87.2 38.3 63.7 123.7 44.4 129.1 91.8 0.1 0.3 0.8 0.5 0.5 0.2 0.3 1.0 0.9 0.4 0.2 0.4 0.5 0.0 0.1 0.1 0.2 0.8 0.3 2.0 2.5 2.1 2.1 1.7 1.9 2.6 3.0 2.6 2.5 2.2 3.0 0.7 0.0 2.3 0.3 4.6 4.8 1.1 2.4 2.2 0.2 1.3 1.7 0.9 4.3 1.9 1.8 0.0 9.8 2.9 6.2 0.0 0.8 4.7 3.8 2.6 2.0 0.0 38.7 1.0 0.8 23.7 3.5 8.6 2.8 0.0 21.1 1.8 2.1 9.5 0.0 0.6 7.8 0.0 6.5 4.2 5.0 0.6 3.5 0.0 1.0 3.9 0.1 2.1 0.5 1.4 0.5 2.9 0.4 18.6 1.4 1.1 0.4 1.4 1.0 6.6 1.4 3.3 24.7 22.6 10.5 2.3 3.1 5.4 2.0 14.1 2.1 ARHGAP23 KIAA1501 ENSG00000275832 "Rho GTPase activating protein 23" Q9P227 17 38419280-38512385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 97.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.4;Hepatic stellate cells: 46.1;Oligodendrocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 296.7;RT4: 115.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019818, HPA047291" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" Cytosol "HPA019818: AB_1844993, HPA047291: AB_2680012" "unprognostic (3.35e-1)" "unprognostic (5.11e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (6.87e-5)" "unprognostic (9.53e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (1.99e-1)" "unprognostic (5.56e-2)" "unprognostic (1.50e-3)" "prognostic unfavorable (3.24e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.38e-5)" "unprognostic (8.36e-2)" "unprognostic (5.83e-2)" "unprognostic (4.57e-2)" "unprognostic (2.25e-1)" 25.6 13.8 36.2 8.3 66.2 10.7 18.8 47.2 54.6 25.9 5.5 22.8 3.0 28.4 3.7 60.8 18.4 7.8 27.3 34.4 37.5 11.8 2.9 28.0 4.1 63.7 59.6 18.1 3.5 3.1 6.2 19.4 54.1 19.9 2.8 8.5 12.8 12.5 10.6 61.1 10.4 11.6 43.0 30.7 13.4 16.1 66.1 5.4 9.5 5.8 11.0 36.3 29.5 97.8 32.5 17.2 15.2 5.1 9.5 31.1 19.6 44.8 49.5 37.7 21.8 56.8 55.1 0.7 35.2 102.5 18.7 296.7 1.7 62.3 26.6 3.5 3.3 0.0 55.1 0.4 47.2 3.0 0.3 18.8 11.8 27.7 17.3 31.0 39.4 6.0 0.6 8.3 21.6 0.0 10.2 6.3 9.0 1.2 6.3 17.0 33.0 10.4 16.0 115.7 3.7 8.8 26.9 0.1 0.3 21.2 6.7 7.9 57.7 62.6 22.9 12.9 12.1 6.5 7.3 1.9 16.3 8.1 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 66.2 47.2 54.6 34.4 37.5 63.7 59.6 54.1 43.0 66.1 97.8 27.2 12.8 1.5 23.8 0.7 9.9 17.5 10.6 9.1 59.4 1.7 3.9 20.4 1.5 13.2 3.7 0.0 27.0 0.2 0.1 0.0 2.9 7.6 8.5 10.0 34.9 0.0 4.0 9.3 1.4 3.1 11.6 3.1 5.7 0.0 4.9 46.1 0.5 5.1 26.9 16.2 0.4 2.0 2.5 4.2 21.0 9.0 1.2 1.8 9.4 0.2 9.6 0.0 20.1 129.2 7.0 0.1 7.2 1.7 15.4 0.0 0.2 8.3 3.4 0.0 10.9 7.6 13.5 2.7 27.5 25.9 16.6 1.8 1.3 0.3 42.2 ARHGAP28 "FLJ10312, KIAA1314" ENSG00000088756 "Rho GTPase activating protein 28" Q9P2N2 18 6729716-6915716 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "placenta: 25.9;testis: 77.5" "Group enriched" "Detected in many" 14 "Early spermatids: 536.8;Late spermatids: 488.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "neutrophil: 3.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 3.0" "Cell line enhanced" "Detected in many" "AF22: 30.4;CACO-2: 32.8;SuSa: 22.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030413, HPA030414, HPA030415" Enhanced Supported "Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" "HPA030413: AB_10601455, HPA030414: AB_10670042, HPA030415: AB_10669598" "unprognostic (8.33e-2)" "unprognostic (8.79e-3)" "unprognostic (3.15e-3)" "unprognostic (6.94e-5)" "unprognostic (1.49e-1)" "unprognostic (2.92e-2)" "unprognostic (1.11e-3)" "unprognostic (1.10e-1)" "unprognostic (7.56e-3)" "unprognostic (9.52e-4)" "unprognostic (1.43e-2)" "unprognostic (3.12e-1)" "unprognostic (4.53e-3)" "unprognostic (3.59e-3)" "unprognostic (6.00e-2)" "unprognostic (3.61e-2)" "unprognostic (2.76e-2)" 4.7 1.9 1.1 1.7 1.2 0.8 2.7 1.7 1.6 8.6 0.8 1.9 1.7 2.9 8.7 1.9 3.1 6.6 2.0 1.5 1.6 8.4 0.9 4.6 1.7 0.4 0.2 10.4 3.8 3.0 0.8 25.9 0.5 3.9 2.3 1.4 0.8 2.2 4.9 2.1 1.8 1.4 0.1 12.6 2.1 77.5 1.1 3.8 2.9 1.6 0.9 5.4 3.0 0.8 0.2 0.2 30.4 3.1 6.3 10.5 4.9 2.2 5.1 2.5 5.3 32.8 0.2 0.2 1.0 0.4 1.7 1.4 0.1 0.8 3.7 1.0 1.8 0.1 2.9 0.2 1.1 0.1 0.1 12.6 0.6 2.7 0.2 0.3 7.8 0.5 0.8 2.5 4.1 0.5 0.5 0.3 9.6 0.4 1.4 0.1 2.7 0.2 0.0 2.9 2.9 11.9 0.1 2.8 0.5 22.6 0.2 0.1 1.3 0.5 13.1 10.1 0.4 0.2 0.1 0.1 5.0 0.3 1.1 0.7 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 3.0 0.1 0.0 0.2 0.0 0.0 1.1 1.2 1.7 1.6 1.5 1.6 0.4 0.2 0.5 0.1 1.1 0.8 8.3 0.0 1.9 6.2 0.1 1.9 1.3 0.2 0.0 1.5 0.9 0.5 1.8 0.0 0.7 1.8 20.9 14.9 0.0 0.0 0.0 1.1 536.8 0.5 14.6 7.9 0.0 0.0 7.1 2.7 2.7 16.1 0.0 0.4 0.0 25.8 4.2 0.2 2.1 0.0 34.4 0.1 0.0 0.3 0.4 488.0 18.3 0.5 0.0 12.2 0.0 0.2 0.0 24.6 3.6 0.7 0.0 14.3 0.1 4.7 0.0 3.8 0.0 0.8 0.0 11.0 5.4 14.3 3.7 0.8 1.4 6.6 0.3 23.7 0.0 1.3 ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 68.3;intestine: 53.2;lung: 39.5;lymphoid tissue: 106.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Cytotrophoblasts: 40.1;dendritic cells: 62.7;Extravillous trophoblasts: 56.6;Hofbauer cells: 40.0;monocytes: 72.4;Syncytiotrophoblasts: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.7;Karpas-707: 100.4;RPMI-8226: 74.7;THP-1: 92.3;U-266/70: 130.8;U-937: 72.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA019816: AB_1853923, HPA079252: " "unprognostic (1.34e-1)" "unprognostic (5.13e-3)" "unprognostic (5.17e-3)" "prognostic favorable (6.02e-4)" "unprognostic (2.26e-1)" "prognostic favorable (7.82e-4)" "unprognostic (1.59e-2)" "unprognostic (2.17e-2)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (5.33e-2)" 11.2 5.5 3.6 43.1 3.4 68.3 5.5 4.4 7.5 4.2 5.1 12.4 7.2 3.5 0.5 5.5 6.7 5.0 4.4 3.3 4.4 7.8 7.4 39.5 58.4 9.1 5.4 2.0 2.7 0.8 4.5 6.0 6.9 5.9 2.6 8.7 6.4 1.5 2.1 3.9 53.2 2.2 7.6 106.1 10.9 3.5 8.1 32.9 9.0 0.8 18.6 6.6 5.5 11.4 11.2 2.1 0.1 12.1 0.0 0.0 27.8 0.1 0.0 0.0 0.0 29.2 13.9 73.7 3.0 0.0 0.4 9.6 2.1 0.6 0.0 54.7 1.0 10.1 22.6 3.5 0.4 48.6 56.2 0.0 2.9 0.1 0.0 0.0 0.1 46.8 6.8 100.4 0.0 0.6 54.5 43.4 7.6 1.9 5.4 52.0 0.3 74.7 0.0 0.2 0.6 0.2 16.8 0.0 4.5 0.7 3.5 92.3 4.8 0.2 1.9 0.2 0.3 130.8 60.2 58.8 0.3 72.1 5.4 6.7 24.4 25.3 45.7 21.2 38.8 15.9 52.2 54.1 22.5 18.3 68.9 53.6 37.0 28.0 20.9 13.3 43.5 59.8 3.6 3.4 4.4 7.5 3.3 4.4 9.1 5.4 6.9 7.6 8.1 11.4 2.0 48.1 8.4 0.0 17.8 0.0 0.0 0.0 0.0 0.0 15.2 11.0 0.0 0.0 1.8 11.0 0.0 40.1 62.7 0.0 0.0 2.6 0.0 4.5 0.7 1.6 0.0 0.0 0.0 3.8 56.6 1.3 0.0 3.5 3.8 0.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 72.4 0.0 0.0 0.0 0.0 7.8 0.0 0.0 15.2 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 75.5 30.2 0.1 0.0 0.0 ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 66.4;Endothelial cells: 48.9;Hepatic stellate cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "HUVEC TERT2: 40.4;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" 47.7 5.9 4.6 4.1 4.2 0.0 41.6 4.1 4.7 8.7 3.0 6.9 3.1 10.9 1.6 4.8 9.8 7.3 35.5 4.1 4.1 15.8 2.9 22.1 3.1 4.7 4.5 3.8 4.2 3.4 4.0 14.7 4.8 8.0 2.0 0.2 5.1 3.5 13.2 7.7 6.5 7.2 4.0 7.9 6.9 2.2 5.2 1.6 12.4 10.9 1.8 12.3 8.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.2 4.1 4.7 4.1 4.1 4.7 4.5 4.8 4.0 5.2 3.6 66.4 0.0 3.0 0.3 0.5 2.8 0.3 0.0 0.6 0.8 0.5 0.4 8.9 2.8 0.0 1.8 0.0 0.0 0.2 0.1 0.0 0.0 3.3 0.4 0.2 48.9 0.0 0.0 0.2 0.0 0.1 1.0 0.0 1.3 0.0 0.0 37.1 0.0 0.1 0.0 0.5 0.0 0.0 1.4 2.8 4.4 0.0 0.5 7.2 11.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.1 0.0 1.6 1.5 0.4 0.2 0.2 1.0 0.1 0.3 0.7 0.0 0.3 ARHGEF2 "GEF-H1, GEFH1, KIAA0651, Lfc, LFP40, P40" ENSG00000116584 "Rho/Rac guanine nucleotide exchange factor 2" Q92974 1 155946851-156007070 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Mitosis, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043437 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 3: Monocytes - Immune response regulation" "HPA043437: AB_2678481" "unprognostic (2.27e-2)" "unprognostic (8.30e-3)" "unprognostic (3.24e-3)" "unprognostic (1.90e-3)" "unprognostic (4.14e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (9.20e-6)" "unprognostic (5.96e-2)" "unprognostic (2.14e-1)" "unprognostic (3.62e-2)" "unprognostic (2.59e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (7.17e-6)" "unprognostic (4.63e-2)" "unprognostic (2.70e-1)" "unprognostic (8.85e-3)" "unprognostic (7.98e-2)" 48.9 12.3 52.6 39.2 80.8 64.0 40.8 69.0 77.8 38.8 18.7 47.3 18.8 37.0 15.2 25.8 42.1 31.1 42.8 55.5 56.2 35.7 13.2 89.9 48.4 85.9 75.9 28.1 15.1 18.5 16.8 32.1 84.1 27.3 28.8 11.1 25.0 15.1 17.8 17.9 45.4 29.9 60.9 69.9 39.9 33.9 77.2 38.6 46.7 16.8 32.6 37.8 31.4 130.6 32.0 25.7 44.0 30.3 41.4 51.9 45.3 69.9 89.4 67.2 71.5 23.3 23.6 79.4 41.9 53.8 35.4 45.7 26.7 22.2 50.9 32.5 22.9 105.1 40.9 14.0 162.4 138.6 87.8 61.1 90.4 100.2 122.1 50.7 55.7 60.5 59.2 94.2 96.2 17.7 70.2 187.2 48.8 53.4 17.0 75.5 61.3 135.9 28.3 19.0 72.1 33.1 30.1 43.6 246.1 43.6 45.0 188.7 73.6 57.7 32.7 50.9 89.8 155.7 171.1 55.6 82.4 68.7 144.6 15.1 20.6 17.1 15.7 18.1 10.8 14.6 9.9 11.3 18.2 13.1 9.6 11.0 31.7 11.0 21.9 8.7 9.9 28.2 52.6 80.8 69.0 77.8 55.5 56.2 85.9 75.9 84.1 60.9 77.2 130.6 26.4 38.5 73.4 2.9 43.9 15.2 28.1 12.6 10.8 54.1 15.7 12.3 6.2 10.0 12.0 16.5 2.1 3.5 32.1 21.1 7.9 15.5 52.9 6.6 10.2 32.3 30.5 48.6 30.8 5.3 22.8 24.8 59.1 13.3 27.9 8.9 23.2 1.0 29.7 1.7 17.0 20.9 16.2 49.0 67.8 16.1 11.5 46.0 24.9 20.6 82.9 12.9 48.4 22.1 105.5 16.5 22.5 10.1 20.0 16.7 9.8 2.2 13.0 3.3 59.2 32.9 30.8 3.1 4.1 11.7 13.8 3.4 29.7 2.1 14.2 40.2 ARHGEF38 FLJ20184 ENSG00000236699 "Rho guanine nucleotide exchange factor 38" Q9NXL2 4 105552620-105708093 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 7.8;pancreas: 6.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 48.5;Breast glandular cells: 17.9;Respiratory ciliated cells: 31.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 2.8;RPTEC TERT1: 14.3;SK-BR-3: 8.0;T-47d: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036510, HPA045484" Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Centrosome "HPA036510: AB_10672357, HPA045484: AB_2679345" "unprognostic (1.49e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (6.19e-3)" "unprognostic (2.09e-2)" "unprognostic (2.24e-3)" "unprognostic (1.85e-1)" "unprognostic (5.47e-3)" "unprognostic (2.79e-1)" "unprognostic (6.14e-5)" "unprognostic (1.17e-1)" "unprognostic (3.53e-3)" "unprognostic (3.16e-8)" "unprognostic (2.33e-3)" "unprognostic (6.16e-2)" "unprognostic (3.19e-3)" "unprognostic (6.45e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 7.8 0.0 0.0 2.5 0.0 2.6 1.9 0.2 5.5 0.1 0.6 3.2 0.0 0.0 0.0 3.9 0.1 3.6 0.0 0.0 0.0 0.0 6.5 0.0 2.0 0.0 0.0 5.7 4.2 0.0 4.9 0.4 0.3 0.5 2.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 2.8 0.3 0.0 0.0 0.1 14.3 0.0 0.0 0.0 0.0 8.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.4 48.5 0.0 0.2 0.0 1.1 1.1 0.0 0.0 17.9 6.1 1.8 4.3 12.6 12.9 0.0 0.2 0.2 9.8 9.8 6.8 1.9 12.6 0.5 0.3 8.4 0.0 0.3 5.8 0.1 0.3 9.2 7.8 0.0 0.0 0.0 0.1 0.1 0.0 0.3 14.8 10.2 0.0 0.2 0.4 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.1 2.4 6.4 0.0 0.1 9.4 4.8 0.5 31.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 11.4 0.8 ARID1B "6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R" ENSG00000049618 "AT-rich interaction domain 1B" Q8NFD5 6 156776020-157210779 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 404.3;Inhibitory neurons: 475.4;Microglial cells: 327.0;Oligodendrocyte precursor cells: 417.7;Oligodendrocytes: 503.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016511, HPA075291" Approved Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA016511: AB_1845008, HPA075291: AB_2686743" "prognostic unfavorable (1.04e-4)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (5.42e-2)" "unprognostic (7.47e-2)" "unprognostic (1.40e-2)" "unprognostic (2.73e-2)" "unprognostic (2.89e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.16e-4)" "unprognostic (2.53e-1)" "unprognostic (5.33e-2)" "unprognostic (1.07e-3)" "unprognostic (2.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-1)" 15.2 12.0 14.6 14.5 13.4 28.7 15.6 29.0 16.0 19.0 2.2 15.9 14.2 17.0 11.3 15.7 18.6 14.4 14.4 20.4 10.1 13.2 9.7 14.6 18.2 13.4 10.9 27.5 17.1 28.2 12.2 11.7 11.1 14.6 12.1 11.7 20.4 12.7 33.6 23.2 15.3 15.8 7.3 18.4 12.5 9.8 12.5 25.4 22.0 25.4 18.8 17.4 17.4 17.2 13.0 19.4 29.6 41.2 24.7 21.5 20.4 14.6 18.6 18.1 18.0 17.7 20.0 43.0 8.1 23.9 22.4 16.5 25.2 23.3 18.1 40.4 18.1 30.6 19.6 22.1 17.1 25.3 21.8 25.5 18.4 27.1 24.6 20.4 25.6 26.8 35.8 32.3 13.2 15.9 29.1 30.5 15.3 18.3 10.5 66.3 12.7 22.9 12.7 24.3 28.0 34.7 28.3 29.4 15.8 15.7 19.6 40.2 26.4 23.4 23.6 22.0 27.5 21.8 18.2 52.7 19.7 30.3 32.0 5.0 2.3 2.3 4.1 1.9 3.7 5.3 3.5 2.8 1.8 6.9 2.9 4.1 4.2 2.4 2.1 9.4 3.7 1.2 14.6 13.4 29.0 16.0 20.4 10.1 13.4 10.9 11.1 7.3 12.5 17.2 85.7 48.1 51.8 282.7 83.3 47.5 22.3 22.3 41.5 36.0 70.9 44.4 36.9 27.1 32.6 126.9 29.2 14.7 103.7 21.8 7.9 40.8 15.0 70.8 124.5 43.9 40.8 37.8 404.3 34.5 7.5 49.9 31.1 78.0 38.7 137.1 33.9 27.3 14.1 47.1 475.4 33.7 20.3 32.6 36.1 19.4 56.8 49.1 30.2 327.0 59.4 21.9 24.7 417.7 503.7 46.6 26.9 62.8 70.2 28.1 26.8 18.4 29.5 29.6 46.0 43.1 56.7 8.0 12.2 39.7 55.7 17.5 51.9 72.9 36.3 27.1 ARL15 "ARFRP2, FLJ20051" ENSG00000185305 "ADP ribosylation factor like GTPase 15" Q9NXU5 5 53883942-54310582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 441.6;Inhibitory neurons: 285.2;Microglial cells: 408.5;Oligodendrocyte precursor cells: 184.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044604, HPA063820" Uncertain Approved "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Plasma membrane, Cell Junctions" "HPA044604: AB_10960542, HPA063820: AB_2685131" "unprognostic (2.18e-1)" "unprognostic (4.32e-2)" "unprognostic (1.82e-2)" "unprognostic (2.41e-2)" "unprognostic (1.08e-1)" "unprognostic (3.70e-1)" "unprognostic (8.52e-3)" "unprognostic (1.16e-2)" "unprognostic (3.05e-2)" "unprognostic (6.56e-2)" "unprognostic (4.26e-3)" "unprognostic (3.86e-1)" "unprognostic (2.48e-3)" "unprognostic (1.35e-1)" "unprognostic (9.15e-2)" "unprognostic (5.60e-2)" "unprognostic (1.08e-1)" 14.0 12.5 6.6 5.6 7.5 1.9 13.0 5.6 10.0 17.7 7.2 10.6 11.9 16.0 7.6 9.8 8.2 14.5 14.0 8.5 7.1 17.9 9.8 7.6 6.3 5.8 6.2 5.7 5.0 3.2 8.5 22.3 6.0 10.0 10.9 7.6 10.5 6.8 3.3 11.3 9.9 16.6 6.1 8.2 8.3 9.3 6.8 10.6 8.4 11.7 8.0 13.6 8.8 6.2 3.2 5.5 8.5 15.6 7.0 7.8 11.8 10.2 15.1 9.4 20.7 21.1 8.0 32.0 14.9 9.1 11.0 7.7 13.2 14.1 12.4 3.2 13.9 36.9 7.1 2.8 2.5 4.5 43.8 10.0 10.1 15.8 9.5 14.2 20.8 7.0 32.4 5.3 6.5 7.7 7.5 4.3 3.0 1.6 3.9 6.2 10.4 0.8 12.8 30.3 11.3 7.1 13.1 6.7 7.9 15.6 8.6 4.7 11.4 5.7 9.6 5.4 6.7 1.8 1.7 34.8 9.9 10.6 9.5 1.1 1.8 2.2 1.3 1.4 0.7 1.0 0.9 0.9 2.4 0.7 0.9 0.7 3.5 0.7 1.2 0.3 2.3 1.2 6.6 7.5 5.6 10.0 8.5 7.1 5.8 6.2 6.0 6.1 6.8 6.2 44.5 3.2 7.7 33.6 6.5 9.7 7.9 5.8 8.0 5.1 4.8 5.8 7.5 5.7 4.5 12.9 14.6 52.5 5.2 7.5 21.5 3.2 3.4 4.1 6.9 35.1 20.9 8.6 441.6 4.9 4.9 8.5 6.6 5.1 2.5 3.2 26.0 4.9 8.4 1.7 285.2 7.6 18.3 8.7 8.7 1.5 4.4 12.5 1.8 408.5 5.0 3.2 6.2 184.5 104.7 6.9 7.6 3.8 4.7 5.4 5.7 10.0 3.9 3.0 6.6 3.6 5.3 1.0 3.5 5.9 10.1 42.7 8.9 24.4 7.1 8.4 ARL4A ARL4 ENSG00000122644 "ADP ribosylation factor like GTPase 4A" P40617 7 12686856-12690958 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 191.1" "Group enriched" "Detected in all" 4 "Early spermatids: 1523.0;Late spermatids: 3892.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 261.3;K-562: 328.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064513 Supported Nucleoplasm,Cytosol NA Yes "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA064513: AB_2685276" "unprognostic (8.29e-2)" "unprognostic (1.34e-1)" "unprognostic (3.94e-1)" "unprognostic (4.97e-2)" "unprognostic (3.88e-2)" "unprognostic (7.43e-2)" "unprognostic (1.34e-2)" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.23e-1)" "unprognostic (3.02e-2)" "unprognostic (3.57e-2)" "unprognostic (7.27e-3)" "unprognostic (1.74e-1)" "unprognostic (9.29e-2)" "unprognostic (9.42e-3)" "unprognostic (9.49e-3)" 31.6 7.9 17.1 16.8 20.1 98.4 55.3 14.3 25.8 38.0 22.5 40.7 29.9 16.8 13.8 60.0 27.7 19.2 15.5 23.0 15.4 8.9 15.6 19.4 18.6 14.4 14.3 8.0 7.2 5.3 9.2 23.6 14.5 21.0 34.7 6.7 86.6 16.5 9.1 88.5 62.7 25.1 14.7 21.0 24.5 191.1 15.4 22.7 19.2 8.7 15.9 21.4 63.8 18.6 45.0 46.7 121.5 261.3 19.3 31.8 0.3 17.9 16.2 28.7 17.2 41.6 32.9 0.3 7.5 25.4 73.4 12.6 27.3 22.6 28.9 9.8 20.4 9.2 61.7 39.3 39.8 39.6 16.0 14.3 88.3 16.7 74.2 18.1 69.0 17.7 328.1 42.5 29.4 19.3 2.2 55.6 44.2 129.2 53.1 0.0 42.4 20.8 37.8 21.3 22.3 20.8 29.5 31.1 6.3 31.3 15.3 32.0 24.3 11.5 40.6 43.5 73.1 19.4 27.2 10.3 29.7 16.5 46.4 8.1 14.8 0.7 11.3 25.7 31.7 41.0 26.8 17.7 14.4 44.7 12.9 10.8 2.2 13.0 32.1 12.8 17.8 13.6 17.1 20.1 14.3 25.8 23.0 15.4 14.4 14.3 14.5 14.7 15.4 18.6 134.0 22.4 20.3 1.0 96.9 339.7 179.1 144.5 70.0 20.9 217.9 230.0 15.8 64.3 86.6 20.2 85.5 152.9 61.0 236.6 27.4 47.8 1523.0 179.1 41.5 162.5 62.6 249.9 11.6 29.6 18.7 46.1 63.2 86.5 80.5 27.7 157.1 21.7 59.5 3.3 3.4 107.1 337.7 168.2 171.1 3892.8 69.0 170.9 120.9 17.8 38.7 11.0 3.1 36.7 8.7 55.3 118.0 26.7 24.4 53.4 641.5 14.6 102.5 125.9 13.1 59.5 55.3 564.1 57.5 134.9 234.7 444.0 98.0 32.4 124.2 89.1 ARL4D ARF4L ENSG00000175906 "ADP ribosylation factor like GTPase 4D" P49703 17 43398993-43401137 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 224.3;Early spermatids: 220.8;Rod photoreceptor cells: 259.6;Squamous epithelial cells: 223.4;Suprabasal keratinocytes: 254.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 32.3;naive B-cell: 36.1" "Lineage enriched" "Detected in all" 4 "B-cells: 36.1" "Cell line enhanced" "Detected in many" "HHSteC: 57.1;hTCEpi: 76.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 8.7;cerebral cortex: 8.8;hippocampal formation: 5.7;olfactory bulb: 4.2;spinal cord: 5.4" HPA060379 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "Golgi apparatus" "HPA060379: AB_2684269" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (2.34e-2)" "prognostic favorable (1.16e-5)" "unprognostic (7.71e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.47e-1)" "unprognostic (4.59e-2)" "unprognostic (4.45e-1)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (7.87e-2)" "unprognostic (2.00e-3)" "unprognostic (3.49e-2)" "unprognostic (6.48e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (9.25e-4)" 21.0 4.3 7.9 2.2 8.7 0.9 7.2 9.1 11.6 29.3 12.6 27.9 2.0 20.2 4.7 82.2 22.1 7.3 12.7 8.1 7.1 30.5 56.4 16.2 1.6 5.6 5.7 9.7 2.2 8.1 21.6 7.7 5.7 11.0 3.5 85.1 16.9 15.2 1.9 44.9 6.0 14.8 5.4 16.7 7.6 32.1 5.7 1.6 38.3 3.4 3.0 28.5 39.5 9.3 8.7 10.9 6.7 5.2 12.5 17.2 3.1 21.0 21.5 14.6 18.8 9.7 37.7 0.1 10.3 22.6 10.0 23.4 4.5 32.0 10.0 1.9 7.5 0.7 8.7 22.5 57.1 2.4 2.1 19.2 76.1 21.3 45.8 13.2 6.3 2.3 1.4 0.4 14.3 0.5 5.4 5.0 7.1 0.8 10.1 9.1 1.5 1.0 24.9 18.8 7.9 5.6 16.5 0.4 15.8 14.4 30.6 8.5 1.3 21.0 6.7 27.2 6.4 2.1 1.1 0.0 25.8 1.9 7.1 0.1 2.8 2.1 5.1 4.3 3.2 32.3 4.2 4.7 8.4 36.1 4.6 5.2 0.0 2.1 1.4 2.5 1.0 4.6 7.9 8.7 9.1 11.6 8.1 7.1 5.6 5.7 5.7 5.4 5.7 9.3 28.8 0.0 1.7 0.7 37.9 224.3 41.4 142.2 132.1 155.5 35.3 60.6 12.7 5.7 49.5 132.4 116.7 39.9 37.4 1.5 76.3 2.3 220.8 55.5 33.3 32.2 11.9 4.0 9.1 1.8 24.1 52.3 5.6 69.6 0.0 20.7 22.9 29.7 8.1 16.8 9.3 5.4 26.4 4.1 77.9 55.3 15.8 16.6 26.6 1.0 1.4 70.1 2.1 2.5 1.3 3.7 0.9 22.6 1.4 9.5 0.3 17.6 7.6 259.6 13.1 11.1 45.1 25.0 9.2 223.4 254.6 105.5 31.7 19.3 4.6 78.1 ARMC7 FLJ22160 ENSG00000125449 "Armadillo repeat containing 7" Q9H6L4 17 75109952-75130272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 39.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024229, HPA053076" Uncertain Supported Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA024229: AB_2059152, HPA053076: AB_2682036" "unprognostic (1.35e-1)" "prognostic favorable (2.98e-4)" "unprognostic (7.73e-2)" "unprognostic (5.84e-2)" "unprognostic (4.15e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.84e-2)" "unprognostic (3.68e-1)" "unprognostic (4.28e-2)" "unprognostic (3.40e-2)" "unprognostic (4.86e-2)" "prognostic favorable (1.27e-4)" "unprognostic (1.93e-2)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.98e-2)" 7.4 6.7 7.3 5.8 7.5 4.1 7.4 12.7 9.0 7.7 7.7 12.4 9.6 7.0 4.8 11.2 6.6 4.7 8.8 7.6 7.7 39.5 13.2 12.3 7.0 7.3 7.1 5.2 7.0 6.6 7.0 5.8 7.6 11.8 6.9 2.7 8.9 6.4 5.5 12.0 11.9 4.0 7.0 14.0 11.4 7.3 7.9 8.2 9.9 3.9 6.4 8.7 9.3 7.9 15.2 30.2 8.9 8.5 7.0 4.3 9.4 8.3 9.0 15.9 14.3 25.3 14.7 9.0 10.8 7.7 8.7 12.4 14.6 6.1 7.6 8.7 23.2 17.5 13.4 15.9 15.5 13.5 16.1 5.6 11.4 10.0 5.8 7.7 14.6 14.5 15.8 17.6 5.3 21.7 25.9 14.8 4.5 32.8 22.6 14.6 18.0 16.8 35.6 27.4 8.3 11.9 15.6 15.7 18.6 15.2 18.4 12.9 11.3 16.1 14.9 6.4 13.1 14.7 5.5 12.7 7.2 9.6 11.8 31.7 13.7 28.5 18.0 9.9 15.8 13.4 12.9 15.1 12.7 10.0 9.8 14.9 18.6 15.7 7.9 11.1 20.8 11.7 7.3 7.5 12.7 9.0 7.6 7.7 7.3 7.1 7.6 7.0 7.9 7.9 6.6 12.8 8.8 1.3 10.4 4.6 2.8 5.8 2.2 6.0 6.0 5.1 2.5 7.2 5.2 22.0 0.0 14.1 10.1 28.6 35.2 8.7 6.2 4.6 3.0 9.0 6.0 1.7 3.0 9.4 8.3 4.1 8.6 5.1 10.8 4.4 14.3 4.6 15.2 0.0 2.9 9.8 6.1 7.5 3.3 12.2 5.3 9.7 12.4 1.9 13.9 3.3 11.3 2.5 1.8 11.3 27.1 3.8 6.4 4.8 15.8 15.4 7.2 3.4 19.7 2.2 4.6 3.8 5.9 4.4 4.5 4.9 8.7 6.6 12.4 3.8 ARMCX2 "ALEX2, GASP9, KIAA0512" ENSG00000184867 "Armadillo repeat containing X-linked 2" Q7L311 X 101655281-101659850 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 154.8" "Cell type enhanced" "Detected in many" "Sertoli cells: 59.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 164.1;NTERA-2: 117.2;SuSa: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005761 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA005761: AB_10600782" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (4.25e-2)" "unprognostic (1.48e-1)" "unprognostic (9.59e-2)" "unprognostic (6.96e-2)" "unprognostic (5.00e-2)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (3.41e-2)" "prognostic favorable (3.45e-5)" "unprognostic (9.06e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.12e-1)" "unprognostic (6.73e-2)" "unprognostic (1.25e-1)" 17.0 46.2 28.7 11.5 29.1 0.5 17.6 22.8 29.7 36.9 26.5 25.4 5.4 30.6 154.8 9.2 28.8 20.6 33.2 29.1 31.6 28.3 3.2 16.8 8.5 25.9 26.2 47.8 18.9 71.2 78.3 26.3 27.5 28.3 7.9 15.3 44.5 67.9 6.2 6.5 13.0 32.3 23.4 21.3 16.3 5.8 28.1 7.7 59.7 7.5 6.5 26.9 20.1 25.4 0.0 0.0 50.8 0.4 43.6 39.4 0.4 56.0 70.4 1.4 1.4 0.0 21.8 0.0 0.0 74.6 0.0 1.5 0.0 1.3 0.6 0.0 2.0 0.2 60.9 0.0 46.4 0.4 0.1 63.7 17.6 43.5 0.4 68.3 59.7 0.0 0.2 0.3 164.1 0.0 0.0 0.6 117.2 3.4 0.3 14.5 88.9 0.3 2.8 0.0 20.4 36.6 0.0 0.2 1.7 90.3 25.9 0.1 13.0 61.9 65.1 38.8 0.4 0.0 0.0 0.2 55.7 0.1 1.2 0.0 0.4 0.0 1.0 0.9 0.4 2.8 0.9 0.9 0.7 4.0 2.4 2.5 0.0 2.8 0.6 0.9 0.7 1.1 28.7 29.1 22.8 29.7 29.1 31.6 25.9 26.2 27.5 23.4 28.1 25.4 10.4 16.0 6.4 8.5 8.2 4.2 16.4 5.8 21.1 12.5 18.0 20.8 28.7 5.7 11.4 33.1 8.4 1.2 2.4 0.1 3.9 9.6 0.2 11.2 23.4 13.3 9.1 3.2 15.4 2.0 0.7 28.4 4.6 15.2 2.5 18.1 19.2 0.7 3.8 1.7 14.3 3.0 2.0 2.4 6.5 1.3 24.2 7.4 5.4 11.2 7.1 9.3 0.0 16.1 14.0 2.2 0.1 24.5 2.8 16.5 0.3 4.3 4.9 11.3 59.2 31.8 23.9 1.4 1.9 3.8 3.0 5.1 2.5 4.6 1.6 7.2 ARMCX3 "ALEX3, GASP6" ENSG00000102401 "Armadillo repeat containing X-linked 3" Q9UH62 X 101622797-101627843 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 88.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000325, HPA000967, HPA001530" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "Golgi apparatus, Cytosol" "HPA000325: AB_1078206, HPA000967: AB_1078208, HPA001530: AB_2666349" "unprognostic (1.67e-1)" "unprognostic (2.14e-1)" "unprognostic (5.23e-2)" "unprognostic (8.69e-3)" "unprognostic (1.73e-2)" "unprognostic (1.47e-2)" "unprognostic (9.72e-3)" "unprognostic (2.19e-2)" "unprognostic (4.77e-2)" "unprognostic (6.80e-2)" "unprognostic (3.38e-3)" "unprognostic (2.12e-2)" "prognostic favorable (1.55e-5)" "unprognostic (3.29e-2)" "unprognostic (3.13e-1)" "unprognostic (1.07e-2)" "unprognostic (1.55e-2)" 34.9 58.9 30.8 24.4 33.0 14.7 32.2 35.4 35.7 45.0 27.6 31.5 20.2 40.9 105.3 18.1 27.7 34.0 51.0 34.1 38.7 37.2 24.6 29.5 21.8 34.5 33.7 38.3 57.4 103.6 47.7 45.4 34.8 44.5 21.8 19.0 59.6 46.7 30.7 11.9 21.5 36.3 35.4 41.3 29.7 12.9 35.5 20.1 49.9 63.6 21.5 31.9 22.5 37.7 26.4 18.8 48.8 23.9 109.4 118.3 10.0 56.5 54.3 23.2 68.3 20.7 21.5 9.5 31.7 64.7 50.8 5.0 34.9 20.2 28.7 21.6 23.2 18.7 64.9 30.2 85.2 18.2 41.5 67.0 27.4 30.9 30.3 65.1 47.6 11.6 15.2 78.9 67.4 10.9 15.0 0.8 24.4 49.5 4.3 19.1 62.2 8.9 36.0 10.1 22.1 18.9 28.3 1.5 63.9 67.7 19.2 19.0 67.5 29.8 18.9 70.8 11.2 69.7 20.9 0.1 50.4 14.5 25.5 43.6 15.3 13.6 14.6 15.8 18.3 15.0 14.0 12.4 15.8 9.8 15.2 10.6 5.6 13.7 16.8 25.8 9.0 14.4 30.8 33.0 35.4 35.7 34.1 38.7 34.5 33.7 34.8 35.4 35.5 37.7 67.4 44.8 36.1 16.3 61.1 37.9 81.2 40.6 42.7 63.1 70.9 42.3 114.6 50.1 48.4 75.4 58.4 55.3 61.1 20.4 37.2 53.9 0.6 42.2 80.9 69.2 82.4 25.6 35.9 30.6 27.4 85.8 33.1 78.8 79.1 45.5 58.2 48.6 50.7 62.2 41.8 67.6 40.7 52.5 84.9 2.8 64.7 72.3 97.8 18.7 27.2 86.6 34.0 28.6 31.0 30.6 22.1 72.6 122.6 75.2 20.1 43.1 25.1 13.3 32.9 57.1 73.2 2.5 0.4 24.6 21.5 114.9 58.0 70.2 32.1 81.2 ARMH3 "C10orf76, FLJ13114" ENSG00000120029 "Armadillo like helical domain containing 3" Q5T2E6 10 101845599-102056193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.2;dendritic cells: 10.5;Extravillous trophoblasts: 14.8;Granulosa cells: 11.5;Hofbauer cells: 12.6;Syncytiotrophoblasts: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050913, HPA053580" Approved Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA050913: AB_2681270, HPA053580: AB_2682198" "unprognostic (5.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "unprognostic (3.41e-2)" "unprognostic (9.41e-2)" "unprognostic (9.55e-2)" "unprognostic (5.28e-2)" "unprognostic (1.92e-2)" "unprognostic (1.18e-1)" "unprognostic (6.03e-3)" "unprognostic (1.40e-3)" "unprognostic (2.76e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-1)" "unprognostic (2.48e-1)" "unprognostic (3.85e-1)" "unprognostic (4.87e-2)" 10.4 9.1 5.9 12.0 7.6 21.8 9.9 10.2 7.3 11.2 8.0 12.5 12.8 10.5 9.4 14.3 10.5 9.2 16.6 5.7 7.3 10.0 12.0 11.8 12.7 7.1 8.2 11.2 10.1 16.4 7.9 11.0 6.1 10.8 13.2 16.3 9.5 10.5 19.7 12.2 12.2 12.9 6.0 13.6 10.3 8.9 6.7 13.1 10.0 19.8 13.3 10.8 10.1 7.9 23.2 17.7 15.5 19.1 12.9 17.3 13.9 20.3 24.0 20.0 16.9 12.2 18.6 17.0 13.5 22.9 14.5 17.7 20.4 22.4 18.3 17.9 18.9 30.3 15.9 14.6 15.2 21.3 26.4 16.0 17.7 22.6 19.9 23.4 15.3 15.3 0.9 15.9 16.6 14.4 16.5 13.8 8.5 18.8 11.6 16.0 28.1 11.0 16.4 18.6 7.3 12.1 15.8 10.9 21.0 15.8 28.8 12.4 15.1 10.5 17.1 9.8 14.7 15.4 17.0 17.1 16.9 23.7 7.9 19.4 7.3 7.4 5.9 8.7 5.5 6.1 6.2 4.5 7.7 7.0 4.8 4.9 1.9 5.2 10.7 7.4 6.0 4.7 5.9 7.6 10.2 7.3 5.7 7.3 7.1 8.2 6.1 6.0 6.7 7.9 8.8 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 7.4 6.0 0.0 0.0 0.0 0.0 0.0 11.2 10.5 0.0 1.9 7.8 0.0 6.9 6.8 1.9 0.0 0.0 0.0 9.7 14.8 2.7 0.0 7.7 0.0 11.5 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 9.9 0.0 0.0 2.2 0.0 0.0 7.6 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 16.3 3.9 5.7 0.0 0.0 ARPC2 "ARC34, p34-Arc" ENSG00000163466 "Actin related protein 2/3 complex subunit 2" O15144 2 218217141-218254356 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001994, HPA008352, HPA052703" Approved Supported Nucleoplasm NA NA 6600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "CAB001994: , HPA008352: AB_1854887, HPA052703: " "unprognostic (7.42e-2)" "unprognostic (4.07e-1)" "unprognostic (1.50e-1)" "unprognostic (3.28e-3)" "unprognostic (2.77e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.23e-2)" "unprognostic (1.90e-2)" "unprognostic (4.07e-2)" "unprognostic (3.95e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (1.07e-7)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (1.01e-2)" "unprognostic (7.41e-2)" 205.4 121.8 114.0 361.4 125.6 544.1 163.5 109.4 130.8 163.1 117.4 252.8 200.3 153.3 161.8 460.5 146.3 211.3 167.3 135.2 123.1 155.0 152.8 259.7 505.2 115.1 114.7 121.3 122.1 115.4 94.7 295.0 116.4 132.1 274.8 77.4 163.6 176.0 385.3 293.4 226.5 291.2 117.8 294.6 251.5 149.7 118.2 298.3 115.3 250.8 626.0 402.0 231.7 125.4 438.3 188.3 264.1 198.0 346.6 463.6 489.4 680.5 640.7 551.2 549.5 588.6 452.0 358.6 347.6 764.7 396.8 492.3 362.6 985.4 645.4 284.2 296.5 362.1 279.0 325.8 386.8 764.2 968.9 310.2 784.1 552.0 454.6 515.1 731.3 294.1 179.5 681.4 858.6 304.3 416.8 888.6 310.8 500.8 201.1 307.2 235.0 488.7 556.8 787.8 156.3 278.8 246.7 265.8 590.0 544.4 192.7 689.2 642.1 709.5 268.1 321.9 507.8 359.8 418.8 624.7 515.1 472.9 548.2 1728.0 1318.5 1975.5 930.7 1773.7 626.1 785.9 720.7 913.6 1330.1 658.5 505.7 750.0 2200.3 698.9 2060.4 734.3 1039.0 2503.2 114.0 125.6 109.4 130.8 135.2 123.1 115.1 114.7 116.4 117.8 118.2 125.4 334.8 285.2 326.6 21.2 506.7 928.5 691.0 1140.2 425.2 89.8 150.3 189.7 145.3 200.1 465.4 172.9 56.3 944.5 902.3 595.0 342.4 585.8 604.0 220.6 288.5 363.5 319.7 144.9 48.5 658.7 1509.4 301.7 242.6 222.4 414.5 600.6 281.3 98.4 1094.0 58.9 33.1 329.4 364.2 779.9 1321.0 759.3 214.0 896.1 414.4 53.4 1721.9 175.3 1336.7 30.7 33.7 919.8 604.5 326.5 529.9 762.7 510.9 342.8 249.6 95.3 302.4 131.6 571.2 324.4 227.9 645.2 970.6 1045.8 694.1 285.6 337.6 1126.5 ARPP21 "ARPP-21, R3HDM3, TARPP" ENSG00000172995 "CAMP regulated phosphoprotein 21" Q9UBL0 3 35638945-35794496 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 260.8;lymphoid tissue: 170.1;skeletal muscle: 85.6" "Group enriched" "Detected in some" 6 "Excitatory neurons: 861.9;Oligodendrocyte precursor cells: 624.8" "Cancer enriched" "Detected in single" 5 "glioma: 1.3" "Region enhanced" "Detected in many" "basal ganglia: 260.8" "Immune cell enriched" "Detected in single" 30 "plasmacytoid DC: 10.1" "Lineage enriched" "Detected in single" 30 "dendritic cells: 10.1" "Cell line enhanced" "Detected in some" "JURKAT: 111.4;MOLT-4: 68.4;REH: 37.3;RH-30: 20.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 254.3" HPA017303 Enhanced Supported Approved Nucleoli,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli Cytosol "HPA017303: AB_1845049" "unprognostic (1.72e-4)" "unprognostic (2.35e-1)" "unprognostic (1.10e-2)" "unprognostic (6.61e-2)" "unprognostic (6.30e-3)" "unprognostic (8.90e-2)" "unprognostic (2.42e-3)" "unprognostic (1.27e-1)" "unprognostic (7.42e-4)" "unprognostic (1.32e-1)" "unprognostic (2.35e-1)" "unprognostic (1.52e-1)" 0.2 0.2 34.8 0.4 260.8 4.5 0.1 85.2 69.9 0.0 0.0 0.4 0.2 0.0 0.0 2.6 0.0 0.0 0.2 48.5 15.7 1.1 2.3 0.1 0.1 14.3 7.8 0.0 0.1 0.0 12.6 0.0 15.6 1.1 0.4 2.9 2.1 0.2 85.6 0.2 0.3 0.0 0.0 0.2 0.2 0.0 9.1 170.1 0.5 48.6 0.4 0.0 0.0 44.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.6 0.0 5.2 0.0 0.0 0.0 0.6 0.0 111.4 0.0 0.2 2.6 0.0 68.4 0.0 0.1 0.0 2.7 37.3 20.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 0.0 0.0 34.8 260.8 85.2 69.9 48.5 15.7 14.3 7.8 15.6 0.0 9.1 44.5 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.8 0.0 0.2 0.2 0.0 0.0 861.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 108.2 0.0 0.0 0.0 0.0 3.5 0.3 0.1 0.0 21.5 0.1 0.0 0.0 624.8 85.7 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.5 0.0 21.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ARR3 ARRX ENSG00000120500 "Arrestin 3" P36575 X 70268305-70281840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 170 "retina: 392.2" "Cell type enriched" "Detected in some" 8 "Cone photoreceptor cells: 1538.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA063129 Enhanced Approved "Golgi apparatus" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "HPA063129: AB_2732696" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.70e-2)" "unprognostic (5.37e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-2)" "unprognostic (2.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-1)" "unprognostic (4.02e-3)" "unprognostic (2.77e-7)" "unprognostic (8.64e-2)" "unprognostic (6.53e-2)" "unprognostic (6.06e-2)" "unprognostic (1.43e-1)" 0.2 0.3 0.1 0.5 0.2 0.5 0.0 0.0 0.1 0.0 0.6 0.3 0.6 0.3 0.0 0.2 0.1 0.4 0.4 0.1 0.1 0.1 0.0 0.2 0.9 0.4 0.3 0.3 0.4 0.0 0.0 0.3 0.3 0.3 0.2 392.2 0.3 0.0 0.3 2.3 0.9 0.0 0.1 0.5 0.4 0.2 0.3 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.1 0.2 1.2 0.8 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.2 0.4 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.5 1.2 0.1 0.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.4 0.1 2.2 0.0 0.2 0.4 0.2 0.3 0.2 0.2 0.4 0.2 0.0 0.0 0.5 0.1 0.3 0.2 0.0 0.0 0.7 0.0 0.1 0.9 0.5 0.7 0.5 0.0 0.5 0.3 0.3 0.5 0.7 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.4 0.3 0.3 0.1 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 46.7 0.0 0.0 0.3 0.0 0.0 0.0 1538.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.2 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 68.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 172.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 ASB1 ASB-1 ENSG00000065802 "Ankyrin repeat and SOCS box containing 1" Q9Y576 2 238426742-238452250 "Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003508 Uncertain Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA003508: AB_1845065" "unprognostic (1.02e-1)" "unprognostic (5.30e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (4.89e-5)" "unprognostic (4.04e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.49e-2)" "unprognostic (5.81e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.56e-4)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" "unprognostic (2.19e-1)" 6.6 5.5 19.1 7.3 18.8 2.9 5.3 14.6 18.1 8.9 9.7 10.1 3.9 10.7 3.7 5.0 8.6 5.3 16.2 17.0 18.6 6.2 6.4 6.4 8.0 18.1 20.0 10.2 5.9 8.4 7.6 3.2 19.5 7.5 4.7 5.5 5.4 7.9 21.1 5.7 8.3 8.1 18.9 7.8 8.0 10.7 19.3 6.7 5.8 23.3 8.5 8.1 6.5 17.1 11.1 15.7 21.2 17.0 13.3 14.0 17.1 29.9 19.8 17.7 19.8 7.7 7.7 9.6 4.0 28.2 39.3 12.0 21.1 47.7 27.7 24.3 17.2 12.1 15.2 19.3 31.1 16.8 15.5 15.0 21.7 51.7 69.7 27.8 7.7 16.7 25.9 6.3 32.9 7.6 9.2 17.8 22.6 9.7 13.2 13.3 43.1 6.4 12.9 15.1 17.1 23.2 9.4 6.9 15.7 12.7 5.2 17.9 16.6 31.8 20.6 25.1 59.9 22.8 15.2 16.5 50.2 5.3 16.2 0.0 0.5 1.0 4.2 0.7 2.2 4.3 3.0 4.1 0.6 2.1 2.5 3.0 0.2 2.1 0.4 2.8 4.1 1.3 19.1 18.8 14.6 18.1 17.0 18.6 18.1 20.0 19.5 18.9 19.3 17.1 2.3 9.6 3.7 7.8 12.2 7.9 27.5 16.4 7.4 10.0 7.4 7.1 45.3 15.7 11.3 9.2 4.2 12.3 12.8 5.2 1.9 15.8 35.2 9.8 8.1 4.0 12.7 19.1 6.1 21.0 28.6 15.0 14.8 4.6 15.9 7.6 5.0 12.5 23.7 10.1 6.1 6.6 10.2 9.5 4.3 19.5 7.8 10.4 7.2 3.7 12.3 9.8 11.3 6.6 8.5 30.4 16.3 14.7 18.5 20.1 8.4 11.3 18.4 6.5 26.3 10.6 16.0 52.1 37.4 7.2 6.8 5.7 13.9 9.9 7.1 15.4 ASB2 ASB-2 ENSG00000100628 "Ankyrin repeat and SOCS box containing 2" Q96Q27 14 93934166-93976739 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 522.2;tongue: 157.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 51.1;Early spermatids: 26.4;Late spermatids: 29.9;Skeletal myocytes: 27.6;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 7 "eosinophil: 50.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 50.8" "Cell line enhanced" "Detected in some" "Karpas-707: 12.8;RPMI-8226: 12.4;SK-MEL-30: 5.9;U-266/70: 42.1;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001546 Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA001546: AB_1078224" "unprognostic (5.65e-4)" "unprognostic (8.19e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.62e-6)" "unprognostic (4.11e-2)" "unprognostic (1.61e-1)" "unprognostic (5.29e-2)" "unprognostic (1.05e-3)" "unprognostic (4.25e-2)" "unprognostic (1.48e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (2.49e-7)" "unprognostic (2.51e-3)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.27e-1)" 2.9 0.8 0.8 5.6 2.1 0.5 1.5 0.0 1.9 12.0 0.0 66.5 4.0 31.6 0.3 4.0 26.6 0.5 78.5 0.6 0.0 0.5 0.5 3.0 7.4 0.1 0.0 2.9 0.3 0.2 0.2 0.2 0.3 14.4 0.4 0.0 6.6 0.9 522.2 2.3 18.3 1.6 0.0 4.2 17.2 0.4 0.3 0.4 1.2 157.6 3.2 30.4 8.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.4 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.0 12.4 0.0 0.2 0.1 0.0 0.0 0.0 5.9 0.0 0.0 2.9 0.0 0.0 0.0 0.2 0.0 42.1 8.6 1.7 0.5 2.6 0.5 0.0 0.2 50.8 1.9 2.7 0.3 1.9 1.7 3.8 4.2 0.4 0.2 0.5 0.1 0.0 7.8 0.4 2.3 1.3 0.8 2.1 0.0 1.9 0.6 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.0 0.3 3.3 0.4 0.1 8.4 0.0 0.2 0.2 0.9 51.1 0.0 2.9 0.0 0.0 0.1 3.0 0.0 0.0 1.4 26.4 1.7 0.3 0.5 0.0 2.7 4.7 0.0 0.5 1.9 1.1 2.5 0.0 0.0 0.0 0.0 0.6 0.0 1.9 0.0 0.0 0.0 0.3 29.9 0.3 5.3 1.8 1.9 5.8 0.8 2.1 0.0 0.7 0.2 0.0 0.4 10.7 0.1 0.0 0.0 0.4 1.1 0.0 27.6 5.0 0.8 8.4 0.1 0.1 2.9 14.5 0.1 0.1 0.3 ASCL2 "ASH2, bHLHa45, HASH2" ENSG00000183734 "Achaete-scute family bHLH transcription factor 2" Q99929 11 2268498-2270588 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.9;salivary gland: 8.0;skin 1: 7.3" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 1042.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 76.1;stomach cancer: 23.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 7.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "BEWO: 25.1;NB-4: 8.1;OE19: 14.2;SCLC-21H: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (2.71e-3)" "prognostic favorable (5.11e-4)" "unprognostic (2.03e-1)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (2.69e-2)" "unprognostic (2.93e-2)" "unprognostic (7.88e-2)" "unprognostic (3.79e-2)" "unprognostic (1.22e-2)" "prognostic favorable (4.73e-4)" "unprognostic (5.85e-2)" "unprognostic (1.45e-6)" "unprognostic (8.86e-3)" "unprognostic (5.48e-2)" "unprognostic (6.12e-4)" "unprognostic (1.07e-3)" 0.3 0.2 1.0 1.2 0.6 0.8 0.7 0.5 0.9 2.4 0.4 3.9 6.9 2.2 0.5 1.6 0.4 0.1 0.1 0.9 0.5 1.7 0.8 0.6 0.7 1.7 2.0 0.1 0.7 0.1 0.1 5.5 1.0 2.3 2.5 0.0 8.0 1.6 0.2 7.3 5.5 0.1 1.1 2.3 2.1 0.8 1.4 0.5 0.5 0.0 0.6 1.5 1.9 2.3 0.0 0.0 0.4 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.7 0.0 8.1 0.6 14.2 0.0 0.0 0.0 0.0 0.0 0.6 20.5 0.1 0.0 0.5 0.0 0.0 2.5 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 3.9 1.2 7.9 2.2 1.7 0.1 0.0 0.5 1.3 0.8 0.0 0.1 1.3 0.9 0.0 1.4 0.0 0.0 0.4 1.0 0.6 0.5 0.9 0.9 0.5 1.7 2.0 1.0 1.1 1.4 2.3 1.2 0.0 0.0 0.0 1.4 13.6 14.1 3.3 23.3 0.0 7.2 3.3 0.9 1.5 0.7 20.2 0.0 18.7 29.2 14.4 7.9 0.2 0.1 1.4 4.7 2.6 78.2 4.4 0.0 0.0 1042.9 1.5 10.2 3.5 0.0 0.0 23.2 0.5 31.1 0.0 0.0 31.4 2.0 22.0 7.0 0.2 1.8 14.3 1.8 3.7 22.6 0.0 110.2 0.0 0.0 0.0 3.6 1.5 1.3 6.5 9.1 0.4 1.0 0.1 0.0 0.1 0.3 0.3 13.7 9.1 4.7 23.3 8.9 0.1 112.1 9.4 ASCL4 "bHLHa44, HASH4" ENSG00000187855 "Achaete-scute family bHLH transcription factor 4" Q6XD76 12 107774385-107776644 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Langerhans cells: 3.1" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA036116 Uncertain NA NA "Cluster 41: Macrophages - Immune response" "HPA036116: AB_10671833" "unprognostic (2.20e-1)" "unprognostic (1.53e-4)" "unprognostic (1.86e-2)" "unprognostic (8.88e-4)" "unprognostic (2.09e-5)" "unprognostic (1.40e-1)" "unprognostic (1.88e-2)" "unprognostic (1.48e-1)" "unprognostic (1.88e-3)" "unprognostic (9.25e-2)" "unprognostic (1.80e-1)" "unprognostic (2.90e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ASF1B FLJ10604 ENSG00000105011 "Anti-silencing function 1B histone chaperone" Q9NVP2 19 14119512-14136613 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.2;testis: 32.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.1;Early spermatids: 36.4;Erythroid cells: 43.6;Extravillous trophoblasts: 35.4;Spermatocytes: 73.2;Spermatogonia: 87.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "neutrophil: 60.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 60.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA054036, HPA069385" Enhanced Supported Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA054036: AB_2682350, HPA069385: " "unprognostic (3.14e-1)" "prognostic favorable (4.45e-5)" "unprognostic (2.41e-3)" "unprognostic (2.40e-1)" "unprognostic (2.15e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (2.87e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.48e-3)" "prognostic unfavorable (2.22e-16)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (3.92e-2)" "unprognostic (4.31e-2)" 0.9 1.4 0.2 5.6 0.3 11.7 1.3 0.3 0.2 2.2 0.1 7.4 5.3 1.0 0.1 10.3 0.7 0.7 0.7 0.1 0.2 1.0 1.3 2.1 12.5 0.3 0.2 0.7 0.7 0.3 0.7 3.6 0.3 0.8 7.7 0.0 1.9 0.3 0.5 3.2 6.0 2.0 0.2 6.7 3.2 32.0 0.3 23.2 0.6 0.4 14.7 1.8 3.2 0.3 64.6 25.3 37.7 28.9 3.8 3.6 16.2 33.1 28.3 63.8 79.5 26.5 31.6 59.1 30.0 17.5 26.5 38.0 41.8 24.1 49.7 54.0 26.9 55.5 48.7 18.6 0.2 39.0 35.1 0.7 1.7 35.8 12.4 7.2 25.1 44.1 50.2 83.8 31.8 75.7 80.8 34.3 17.3 69.1 56.7 77.0 56.0 51.6 20.1 28.3 46.0 16.5 39.8 29.2 17.4 10.3 22.1 41.5 10.6 36.0 21.6 91.0 56.6 43.2 46.5 80.3 28.0 71.9 36.1 0.7 6.2 1.5 1.7 8.0 0.9 1.1 1.5 2.0 1.2 0.9 0.9 1.7 60.1 1.7 8.5 0.5 5.1 3.2 0.2 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.3 0.2 0.3 0.3 1.0 0.0 0.6 0.3 5.6 2.5 2.4 4.5 1.2 0.1 4.8 8.5 1.2 1.5 1.1 0.0 0.0 36.1 3.8 11.7 0.0 1.0 36.4 2.1 1.3 2.1 1.2 43.6 0.5 1.2 35.4 4.1 23.4 2.3 4.5 9.2 0.4 0.3 21.5 0.0 0.4 9.9 8.2 5.6 5.6 29.1 0.0 5.0 1.8 1.0 2.1 0.3 4.1 0.0 0.5 1.1 2.2 0.7 20.1 1.0 2.4 0.3 0.2 0.9 0.0 1.1 3.3 73.2 87.8 8.3 1.1 10.4 5.3 3.0 20.9 2.4 ASIC2 "ACCN, ACCN1, ASIC2a, BNaC1, BNC1, hBNaC1, MDEG" ENSG00000108684 "Acid sensing ion channel subunit 2" Q16515 17 33013087-34174964 "Plasma proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 13.0;cervix: 3.4;endometrium 1: 3.4;retina: 4.6" "Group enriched" "Detected in some" 8 "Excitatory neurons: 1786.2;Inhibitory neurons: 666.4" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.0;RPTEC TERT1: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052112 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA052112: AB_2681733" "unprognostic (3.40e-1)" "unprognostic (2.45e-2)" "unprognostic (8.50e-2)" "unprognostic (7.33e-2)" "unprognostic (1.88e-3)" "unprognostic (5.29e-2)" "unprognostic (4.88e-2)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.29e-2)" "unprognostic (1.28e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (1.44e-1)" 0.0 0.6 13.0 0.0 11.4 0.0 0.1 4.4 10.3 3.4 0.0 0.1 0.4 3.4 0.0 0.0 0.6 0.0 0.0 12.4 6.0 1.1 0.0 0.0 0.0 6.2 6.0 0.0 0.0 0.0 0.5 0.0 3.3 0.1 0.1 4.6 0.0 0.5 0.0 0.1 0.3 1.4 5.8 0.0 0.0 0.3 6.2 0.0 0.0 0.0 0.0 0.0 0.1 8.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 11.4 4.4 10.3 12.4 6.0 6.2 6.0 3.3 5.8 6.2 8.2 0.0 0.0 0.0 17.0 0.0 0.3 0.0 0.0 0.0 25.7 0.0 0.0 1.3 0.0 0.0 9.2 2.1 0.0 0.0 0.1 0.0 0.1 16.3 0.1 0.8 0.1 6.0 0.0 1786.2 0.0 0.0 0.3 0.0 0.4 0.0 0.2 0.0 0.0 0.1 10.1 666.4 1.3 0.0 0.0 0.0 47.1 0.3 0.1 1.8 26.2 0.0 0.5 0.0 144.3 22.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.0 0.2 0.3 0.6 0.0 0.0 0.0 0.1 0.0 1.2 0.0 ASIP "AGTIL, ASP" ENSG00000101440 "Agouti signaling protein" P42127 20 34194569-34269344 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 14.8;heart muscle: 28.0;ovary: 41.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.4;dendritic cells: 44.1;Hofbauer cells: 15.1;Leydig cells: 12.5;Peritubular cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 356 "plasmacytoid DC: 134.8" "Lineage enriched" "Detected in single" 356 "dendritic cells: 134.8" "Cell line enhanced" "Detected in some" "CACO-2: 3.2;HSkMC: 2.4;SK-MEL-30: 1.9;U-698: 1.9" "Not detected" "Not detected" HPA048636 Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA048636: AB_2680471" "unprognostic (4.81e-2)" "unprognostic (7.46e-2)" "unprognostic (1.97e-3)" "unprognostic (3.26e-2)" "unprognostic (2.24e-1)" "unprognostic (3.07e-2)" "unprognostic (5.13e-2)" "unprognostic (4.57e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (5.53e-6)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" 1.4 0.6 0.2 0.0 0.5 0.3 2.4 0.1 0.4 4.2 0.0 0.5 0.0 2.0 14.8 0.1 4.0 0.1 28.0 0.1 0.1 0.9 1.3 0.3 0.4 0.2 0.1 41.7 0.1 0.0 0.6 0.2 0.6 1.5 0.0 0.3 0.7 0.2 0.9 5.7 0.8 0.0 0.0 0.3 0.3 1.5 0.2 0.2 0.3 1.2 0.5 0.5 1.1 0.3 0.0 1.1 0.4 0.4 0.2 0.7 0.1 0.1 0.0 0.0 0.0 3.2 0.0 1.2 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.7 0.3 0.5 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.1 0.0 0.7 0.6 0.9 0.0 0.3 0.2 1.7 0.0 0.1 0.6 0.3 0.3 1.4 0.0 0.1 0.2 0.2 0.0 0.2 1.9 0.5 0.3 0.2 0.3 0.5 0.5 0.0 0.3 0.4 0.4 1.9 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 134.8 0.0 0.6 0.2 0.5 0.1 0.4 0.1 0.1 0.2 0.1 0.6 0.0 0.2 0.3 0.4 0.0 0.6 1.3 0.8 2.5 0.0 0.0 0.0 0.0 0.3 0.5 27.4 0.0 0.0 0.0 0.0 0.2 44.1 0.0 1.9 0.0 1.1 0.3 9.2 1.2 0.0 0.0 2.1 0.0 0.2 5.6 0.0 0.4 0.0 0.2 2.5 5.8 15.1 0.0 1.8 0.0 0.0 0.8 7.0 1.7 12.5 2.1 1.8 1.0 0.3 0.0 0.0 2.5 2.5 0.1 0.0 10.5 0.0 0.1 0.0 8.3 0.0 0.0 6.6 0.1 0.6 1.7 1.9 0.2 3.1 0.8 0.6 1.0 0.0 0.1 ASPHD2 FLJ39838 ENSG00000128203 "Aspartate beta-hydroxylase domain containing 2" Q6ICH7 22 26429260-26445015 "Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;skin 1: 11.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.8;Early spermatids: 25.3;Late spermatids: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.3" "Group enriched" "Detected in many" 4 "dendritic cells: 2.4;monocytes: 5.3" "Cell line enhanced" "Detected in many" "Karpas-707: 21.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000820 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "HPA000820: AB_1078231" "unprognostic (1.12e-1)" "unprognostic (1.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.71e-1)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-2)" "unprognostic (8.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.06e-5)" "unprognostic (6.55e-2)" "unprognostic (9.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.11e-2)" 0.7 0.6 8.0 2.5 16.9 1.5 0.6 10.4 9.0 1.5 0.6 2.0 1.2 1.2 6.2 1.5 0.5 1.1 0.4 8.3 7.0 6.1 0.3 0.9 4.4 4.1 4.3 0.6 0.5 1.7 6.6 1.1 5.5 1.1 2.0 5.6 1.0 0.7 0.4 11.1 1.6 0.7 3.1 2.8 8.2 1.9 6.4 1.3 2.0 0.1 3.3 2.3 1.1 5.8 1.6 0.9 4.1 6.5 0.6 0.3 2.2 2.1 4.5 4.3 6.2 0.0 0.4 1.4 0.5 2.0 4.3 1.9 4.5 7.2 2.3 9.7 6.1 0.3 0.0 0.3 4.1 2.4 1.1 0.7 3.4 2.2 3.0 4.7 4.6 3.6 1.7 21.9 1.3 0.4 1.8 1.0 4.0 8.5 0.9 12.2 2.3 3.7 6.0 0.6 11.0 4.8 2.1 0.3 2.4 2.2 0.2 3.5 4.3 2.7 13.4 0.6 4.4 6.3 1.7 2.8 4.1 8.6 1.8 0.0 1.2 0.5 0.3 3.3 0.9 0.9 0.7 0.7 2.1 0.9 0.4 0.4 0.3 0.0 5.3 2.4 0.4 0.4 8.0 16.9 10.4 9.0 8.3 7.0 4.1 4.3 5.5 3.1 6.4 5.8 0.3 0.0 1.1 4.2 5.1 1.8 1.4 2.1 0.0 24.8 0.9 0.9 0.6 1.5 0.9 0.0 10.4 0.3 6.8 3.3 0.0 1.2 25.3 0.7 0.5 1.1 0.0 0.0 14.1 0.7 13.2 1.3 8.2 1.5 0.0 0.9 1.1 0.1 1.5 6.7 9.7 4.3 2.0 2.8 5.7 25.1 0.9 4.1 1.8 1.0 5.3 2.4 2.1 4.5 1.1 5.9 0.8 0.7 12.1 4.6 0.1 0.7 0.8 11.3 0.0 0.4 0.7 1.1 3.3 0.6 1.1 1.1 2.8 0.4 2.0 4.2 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.3;smooth muscle: 110.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 67.2;Fibroblasts: 94.6;Microglial cells: 24.4;Sertoli cells: 39.5;Smooth muscle cells: 73.5;Suprabasal keratinocytes: 27.0" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Cell line enhanced" "Detected in some" "ASC TERT1: 16.0;BJ hTERT+: 5.7;HHSteC: 23.2;HSkMC: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 2100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" 29.6 7.6 1.2 5.7 1.7 0.1 11.8 2.3 2.0 40.9 0.9 25.5 9.6 69.6 9.7 10.1 16.9 65.9 95.3 1.2 1.2 11.2 41.1 14.3 3.0 1.3 1.2 7.1 13.4 3.8 2.5 4.3 1.6 4.7 11.3 0.2 3.2 11.7 7.8 12.1 17.6 110.5 1.0 2.3 12.0 1.2 1.8 2.5 11.1 19.8 5.5 13.4 5.0 1.7 0.1 0.0 0.0 0.0 1.4 16.0 0.2 2.6 5.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 23.2 0.2 0.0 4.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 1.2 1.7 2.3 2.0 1.2 1.2 1.3 1.2 1.6 1.0 1.8 1.7 12.9 0.0 1.1 0.3 0.1 67.2 0.1 0.0 0.0 0.4 0.4 0.1 8.5 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 4.2 6.8 0.0 0.0 2.0 0.0 0.1 94.6 0.5 0.2 1.3 0.1 13.9 0.4 0.2 0.0 1.7 0.0 0.0 0.0 13.5 0.6 5.9 0.8 14.2 24.4 0.0 0.1 0.0 1.5 1.1 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.7 0.6 39.5 4.3 73.5 0.0 0.1 0.3 27.0 0.0 1.7 0.3 0.0 0.0 ASPRV1 "FLJ25084, SASPase, Taps" ENSG00000244617 "Aspartic peptidase retroviral like 1" Q53RT3 2 69960089-69962265 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "skin 1: 424.0" "Cell type enhanced" "Detected in some" "NK-cells: 3.1;Oligodendrocytes: 4.2;Spermatogonia: 3.3;Suprabasal keratinocytes: 10.7" "Group enriched" "Detected in many" 8 "head and neck cancer: 23.1;melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 8.7" "Lineage enriched" "Detected in single" 10 "granulocytes: 8.7" "Cell line enhanced" "Detected in some" "NB-4: 2.9;REH: 4.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034809, HPA034810" Enhanced Approved Cytosol NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 14: REH - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA034809: AB_2674343, HPA034810: AB_10601456" "unprognostic (4.75e-4)" "unprognostic (1.90e-3)" "unprognostic (2.34e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (1.17e-2)" "unprognostic (1.93e-3)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (4.19e-3)" "unprognostic (1.27e-1)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.84e-2)" "unprognostic (2.43e-2)" 2.6 2.1 5.8 0.9 7.3 0.9 17.1 6.1 6.6 3.1 3.0 1.7 1.6 2.5 2.6 0.9 2.3 1.1 1.8 5.3 6.0 2.2 1.9 1.7 1.0 7.2 6.7 4.8 0.7 0.2 4.0 0.9 6.5 2.2 0.6 1.5 1.3 1.3 4.4 424.0 1.7 1.2 6.0 3.9 1.2 3.6 6.5 2.1 1.3 2.1 1.0 1.5 4.5 9.3 0.0 0.3 0.9 1.9 1.2 0.4 0.2 0.2 0.4 0.2 0.1 0.6 0.0 0.7 0.1 0.2 0.2 0.2 0.8 0.1 0.2 1.3 2.5 1.5 0.2 0.6 0.4 1.3 1.0 0.5 0.4 0.2 0.4 0.3 0.2 1.6 0.5 1.9 0.2 0.3 1.1 2.9 1.0 0.2 0.2 4.9 0.5 0.3 0.0 0.0 1.0 0.2 0.1 0.7 0.8 0.2 0.0 0.5 0.1 0.0 0.9 0.0 0.2 2.0 1.3 1.4 0.1 0.9 1.0 0.0 0.1 1.5 0.5 0.1 0.5 0.0 0.2 0.4 0.0 0.1 0.1 0.4 8.7 0.3 0.0 0.8 0.7 0.4 5.8 7.3 6.1 6.6 5.3 6.0 7.2 6.7 6.5 6.0 6.5 9.3 1.1 0.0 0.0 1.3 0.0 0.4 0.1 0.2 0.0 1.1 0.5 0.9 2.6 0.0 0.1 1.8 0.0 0.3 0.1 0.5 0.0 0.1 0.1 0.4 0.5 0.8 0.0 0.0 1.0 0.2 0.0 0.7 0.0 0.4 0.0 1.1 1.4 0.1 0.2 0.0 1.5 0.9 0.0 0.3 0.6 0.5 0.9 0.3 0.0 1.0 0.2 1.2 3.1 1.5 4.2 0.3 0.0 0.7 0.1 0.2 1.1 0.9 0.2 1.6 0.0 0.7 1.1 1.4 3.3 0.0 10.7 0.4 0.2 0.5 0.2 0.1 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 79.1;Spermatocytes: 106.0;Spermatogonia: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 294.4" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 2.9 3.4 3.8 7.7 3.6 26.5 6.8 2.6 3.9 12.8 2.0 5.3 5.0 4.3 3.8 6.8 3.4 3.2 5.8 3.2 4.5 1.4 9.9 4.1 14.4 2.9 3.8 7.0 3.3 1.9 3.9 4.8 2.6 10.3 6.9 1.4 4.3 4.7 9.3 6.8 5.2 4.1 2.8 4.9 4.7 18.9 5.1 28.3 3.9 3.2 12.8 4.8 3.9 2.8 103.7 39.6 55.0 19.0 9.7 12.3 24.3 79.2 27.2 66.8 73.9 30.1 43.8 67.2 23.6 25.2 26.5 48.3 74.2 25.6 106.1 94.3 39.0 121.2 41.0 61.4 3.8 44.6 57.4 4.1 3.8 63.6 21.0 14.3 20.7 38.6 57.7 66.4 50.4 107.1 129.5 32.8 10.0 77.8 38.4 66.5 65.6 36.4 23.8 46.7 70.2 30.5 114.4 294.4 20.8 22.1 60.2 41.2 13.0 50.4 69.3 40.2 96.6 21.2 40.7 60.8 32.9 72.9 40.4 5.3 0.8 3.3 1.6 0.8 2.2 2.6 2.3 2.7 1.4 1.5 1.5 1.7 0.2 2.5 1.9 0.1 4.6 1.0 3.8 3.6 2.6 3.9 3.2 4.5 2.9 3.8 2.6 2.8 5.1 2.8 4.8 6.4 11.0 9.4 18.5 15.8 27.9 9.1 14.2 2.8 17.3 21.2 27.3 2.8 10.2 3.7 4.2 14.9 15.3 9.0 1.9 3.5 54.9 7.9 17.3 9.6 1.2 79.1 25.6 2.2 26.2 17.1 13.3 17.5 14.5 37.9 7.1 16.3 11.2 1.7 16.4 13.1 4.1 8.2 6.9 24.4 7.5 11.7 1.8 14.0 6.3 6.3 17.5 11.6 2.8 3.5 4.3 13.9 34.0 20.7 3.1 1.0 5.4 1.9 0.0 9.5 17.5 106.0 82.4 23.7 12.1 13.5 22.8 3.7 14.6 24.5 ATF6 ATF6A ENSG00000118217 "Activating transcription factor 6" P18850 1 161766298-161977574 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005935 Approved NA NA 46000000 "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "HPA005935: AB_2667472" "unprognostic (1.31e-1)" "unprognostic (5.15e-3)" "unprognostic (3.18e-2)" "unprognostic (8.43e-3)" "unprognostic (1.59e-1)" "unprognostic (5.58e-3)" "unprognostic (1.24e-1)" "unprognostic (5.32e-2)" "unprognostic (3.37e-2)" "unprognostic (3.24e-1)" "unprognostic (6.09e-3)" "unprognostic (3.38e-1)" "unprognostic (7.55e-2)" "unprognostic (2.03e-1)" "unprognostic (2.43e-1)" "unprognostic (1.56e-2)" "unprognostic (7.57e-3)" 13.6 10.1 7.2 13.9 8.4 12.6 11.5 8.3 7.5 8.4 13.6 9.9 9.9 10.6 18.9 11.0 8.9 11.3 9.4 7.2 9.9 14.6 22.0 11.4 10.6 10.2 9.4 9.0 34.4 18.9 7.1 18.0 10.5 10.7 11.2 16.7 13.3 10.3 8.9 11.2 9.4 12.8 10.0 11.3 11.2 10.1 8.0 8.4 15.1 9.5 11.1 13.7 7.9 11.9 23.3 17.9 15.1 22.4 18.6 17.7 26.7 27.8 25.3 17.7 19.2 11.6 38.2 16.9 39.6 34.6 19.9 34.0 15.1 18.6 17.6 23.2 12.9 15.9 22.6 12.7 40.3 29.7 40.6 18.3 29.0 18.2 53.3 23.8 40.3 22.7 37.9 19.2 19.3 23.0 15.9 17.3 12.2 24.5 23.1 13.7 21.4 39.2 19.3 11.1 9.1 13.8 33.3 19.8 41.0 32.9 24.5 39.2 54.4 23.2 21.9 8.7 31.5 28.0 29.2 20.4 28.2 5.1 29.0 9.7 17.8 12.0 9.2 18.3 9.0 8.7 8.3 7.7 12.8 9.5 9.5 9.7 33.2 7.4 24.4 5.7 9.6 10.6 7.2 8.4 8.3 7.5 7.2 9.9 10.2 9.4 10.5 10.0 8.0 11.9 40.5 102.5 85.1 41.8 31.4 34.8 45.4 28.4 18.2 38.6 38.0 25.4 21.6 25.8 67.0 51.5 50.1 49.2 23.2 30.5 7.9 45.9 13.0 27.1 25.3 49.8 37.1 17.9 79.9 37.6 43.1 46.2 23.9 40.2 54.3 24.0 37.5 53.5 50.3 26.9 69.7 28.2 30.5 59.5 59.4 10.8 23.0 66.6 26.6 103.0 62.0 34.1 21.6 60.3 105.8 35.9 15.6 24.5 53.9 43.3 22.3 18.8 61.7 29.9 6.6 61.3 31.8 43.1 30.5 22.7 47.7 103.0 29.0 22.1 22.9 44.1 ATG2A KIAA0404 ENSG00000110046 "Autophagy related 2A" Q2TAZ0 11 64894546-64917211 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 16.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038715 Uncertain Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "HPA038715: AB_10673474" "unprognostic (3.05e-2)" "unprognostic (2.33e-1)" "unprognostic (7.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.42e-1)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.79e-5)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (3.37e-1)" "unprognostic (1.15e-1)" 16.4 20.1 11.4 6.5 10.9 60.2 16.9 8.6 40.1 19.9 11.4 18.9 7.5 18.2 1.8 15.7 19.2 4.2 18.4 11.5 9.8 22.0 59.2 24.2 6.1 13.9 12.3 24.9 22.7 4.9 21.6 4.9 12.7 21.6 2.6 1.9 15.2 5.7 26.7 34.9 21.4 3.3 9.0 25.7 23.2 15.3 11.4 5.4 19.3 4.4 3.3 17.7 15.6 10.4 13.2 12.6 4.4 12.0 5.7 4.0 12.3 7.1 10.3 9.4 6.8 11.0 9.9 9.3 14.7 6.0 12.0 10.8 4.5 8.3 2.5 9.1 15.7 8.7 19.1 10.0 8.4 6.5 18.2 10.9 7.1 11.8 6.3 5.4 7.9 9.5 16.1 7.3 4.1 21.3 7.8 21.9 5.1 3.5 14.3 8.6 7.1 13.5 5.0 10.9 16.5 6.7 10.6 14.6 13.3 3.3 14.3 8.1 10.1 9.0 8.6 18.3 5.3 14.7 5.5 6.5 13.0 5.2 5.6 3.0 2.0 2.2 2.5 2.1 2.1 0.8 1.7 2.2 1.4 0.9 1.3 2.4 16.9 1.8 1.7 2.4 0.9 1.2 11.4 10.9 8.6 40.1 11.5 9.8 13.9 12.3 12.7 9.0 11.4 10.4 9.8 9.6 16.2 20.2 17.0 28.9 8.7 35.7 16.5 16.6 15.8 10.3 8.1 7.2 17.6 9.2 33.3 12.7 40.1 38.8 1.9 10.2 2.5 12.4 9.2 10.2 35.9 16.2 7.6 10.3 5.3 12.6 16.8 24.4 9.5 15.4 7.9 23.2 10.9 13.5 8.4 17.6 24.4 20.1 19.9 3.6 12.8 24.2 30.2 5.6 11.9 12.3 19.6 6.6 7.1 14.9 21.7 10.1 27.3 12.2 26.8 6.6 13.3 26.0 13.1 11.6 10.6 9.0 6.2 16.3 38.4 66.9 40.2 27.2 19.0 15.9 ATG9B "APG9L2, FLJ14885, NOS3AS, SONE" ENSG00000181652 "Autophagy related 9B" Q674R7 7 151012209-151024499 "Metabolic proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 8.3;skin 1: 11.5" "Cell type enhanced" "Detected in many" "Early spermatids: 50.7;Endometrial ciliated cells: 28.6;Late spermatids: 30.3;Respiratory ciliated cells: 25.9;Syncytiotrophoblasts: 115.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.9" "Lineage enriched" "Detected in many" 5 "T-cells: 8.9" "Group enriched" "Detected in some" 5 "BEWO: 13.0;CAPAN-2: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.59e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (1.53e-3)" "unprognostic (1.05e-3)" "unprognostic (2.79e-3)" "unprognostic (6.66e-2)" "unprognostic (2.38e-3)" "unprognostic (6.76e-2)" "unprognostic (2.02e-1)" "unprognostic (5.06e-2)" "unprognostic (2.08e-6)" "unprognostic (2.82e-2)" "unprognostic (2.70e-2)" "unprognostic (6.34e-2)" "unprognostic (2.63e-1)" 0.0 0.5 1.1 0.4 1.7 0.2 0.2 0.4 1.0 1.7 0.3 0.0 0.0 0.4 1.1 8.3 1.0 0.2 0.0 0.5 2.1 0.0 0.0 0.2 0.8 2.0 1.7 0.1 0.0 0.0 1.5 4.1 1.1 0.2 0.0 0.8 0.5 0.0 0.2 11.5 0.0 0.0 1.0 0.1 0.1 2.0 2.1 0.3 0.1 0.0 0.8 0.1 1.6 0.4 0.6 0.0 0.7 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.1 4.2 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.6 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.5 0.4 0.6 0.0 1.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 1.1 0.0 1.0 0.9 5.0 1.3 0.0 1.6 8.9 3.4 0.0 0.4 0.1 0.7 5.4 1.4 1.1 1.7 0.4 1.0 0.5 2.1 2.0 1.7 1.1 1.0 2.1 0.4 0.4 0.0 0.0 0.0 2.8 0.0 0.2 1.9 0.6 4.0 0.7 0.9 1.4 1.5 1.6 0.0 0.0 10.2 1.5 0.3 0.0 0.3 50.7 28.6 3.3 1.1 0.0 0.0 2.7 0.2 2.5 0.5 0.0 15.4 14.7 7.8 2.2 0.0 1.9 0.0 7.7 0.0 4.1 0.3 0.4 30.3 0.6 0.8 0.0 0.0 0.3 0.5 1.0 0.5 0.6 3.8 0.0 0.7 0.4 0.3 0.0 0.1 25.9 0.6 0.0 0.0 0.9 19.8 12.7 0.8 0.3 115.5 4.7 0.1 0.2 1.9 ATOH8 "bHLHa21, FLJ14708, HATH6" ENSG00000168874 "Atonal bHLH transcription factor 8" Q96SQ7 2 85751344-85791383 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 54.7" "Cell type enhanced" "Detected in many" "Adipocytes: 123.8;Endothelial cells: 41.7;Hepatocytes: 39.1;Muller glia cells: 32.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 15.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.2;fHDF/TERT166: 6.8;hTERT-RPE1: 5.0;RH-30: 9.5;RT4: 5.6;TIME: 7.9;U-2197: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028406 Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA028406: AB_2672587" "unprognostic (7.70e-2)" "unprognostic (1.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (2.84e-3)" "unprognostic (2.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.78e-1)" "unprognostic (6.28e-3)" "unprognostic (1.56e-1)" "prognostic favorable (8.98e-6)" "unprognostic (3.32e-2)" "prognostic favorable (3.80e-5)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-2)" 33.8 1.8 2.1 0.3 2.2 0.0 29.9 2.7 1.6 20.9 0.5 8.8 0.2 25.9 0.2 5.6 19.4 0.4 30.6 1.5 5.1 7.3 25.1 25.6 0.8 5.7 4.9 15.0 4.2 0.2 5.4 0.3 5.3 17.4 0.4 0.6 5.2 1.9 54.7 19.9 8.9 1.3 1.6 12.2 9.4 2.1 3.1 0.2 48.5 2.0 0.1 21.7 20.6 3.3 0.0 1.1 4.1 6.2 3.0 0.4 0.0 3.4 0.5 0.8 0.3 0.0 0.0 0.0 1.1 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.1 1.6 0.0 0.0 2.1 0.0 0.0 0.0 5.0 0.6 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 9.5 0.0 0.0 5.6 3.0 1.4 0.6 0.0 0.6 0.0 0.0 0.0 7.9 1.2 0.0 5.5 0.0 0.0 0.0 0.0 0.8 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.2 2.7 1.6 1.5 5.1 5.7 4.9 5.3 1.6 3.1 3.3 123.8 9.6 18.3 10.7 0.3 2.5 8.5 11.8 0.6 0.4 0.5 0.8 13.2 5.7 17.5 1.8 0.0 0.1 0.1 1.1 0.0 11.9 13.6 5.9 5.7 41.7 4.2 0.0 0.3 2.3 0.6 11.4 1.1 20.5 1.3 5.3 5.7 39.1 3.2 0.0 0.3 2.2 6.1 3.1 4.0 25.9 3.4 4.3 1.8 5.6 0.6 32.3 0.0 14.6 3.1 1.0 5.5 0.4 0.0 4.5 0.0 0.6 2.4 1.3 0.0 12.2 11.6 3.0 2.7 0.2 1.4 0.3 0.5 0.1 1.0 2.3 ATP10A "ATP10C, ATPVA, ATPVC, KIAA0566" ENSG00000206190 "ATPase phospholipid transporting 10A (putative)" O60312 15 25677271-25865184 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0" "Cell type enriched" "Detected in many" 6 "Microglial cells: 216.4" "Cancer enhanced" "Detected in all" "melanoma: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 23.0;fHDF/TERT166: 22.9;HMC-1: 19.4;SK-MEL-30: 21.9;U-2197: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041496, HPA042509" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041496: AB_2677513, HPA042509: AB_2678032" "unprognostic (3.70e-1)" "unprognostic (2.83e-2)" "unprognostic (2.30e-4)" "unprognostic (1.18e-1)" "unprognostic (9.46e-2)" "unprognostic (2.91e-2)" "unprognostic (2.67e-1)" "unprognostic (4.95e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" "unprognostic (4.89e-2)" "unprognostic (9.42e-2)" 6.5 8.7 13.7 2.7 9.3 2.5 5.3 6.0 8.9 2.0 0.7 3.2 0.8 1.5 0.1 1.9 2.3 3.7 2.0 5.9 5.8 5.8 0.6 7.1 1.8 9.9 9.7 1.1 1.4 3.5 2.1 1.7 9.5 2.2 0.8 0.1 7.9 0.6 0.6 2.5 3.0 2.8 5.9 1.5 3.2 4.3 15.0 1.1 2.5 0.7 1.1 2.5 1.4 4.9 0.0 5.7 1.3 0.0 2.2 2.8 0.0 23.0 9.3 6.1 9.9 0.0 0.0 0.0 1.6 22.9 0.0 0.0 9.3 1.2 0.4 0.0 0.2 0.0 0.0 0.1 0.1 0.0 19.4 0.9 0.0 0.6 0.0 2.5 0.0 1.2 0.0 0.0 3.3 0.0 1.2 0.0 1.5 0.0 1.5 4.4 4.6 2.8 9.9 0.0 0.0 0.1 0.0 0.0 21.9 0.0 7.4 1.2 0.0 8.9 0.2 12.7 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.0 0.3 0.5 0.1 0.0 0.7 0.6 0.0 1.2 0.0 1.0 0.1 0.3 13.7 9.3 6.0 8.9 5.9 5.8 9.9 9.7 9.5 5.9 15.0 4.9 0.3 32.1 8.6 2.0 0.8 1.0 0.0 2.7 0.6 0.2 2.6 1.8 1.7 1.5 5.3 0.0 0.0 0.0 11.1 0.1 0.0 0.5 23.2 2.8 2.8 4.2 0.0 0.0 4.5 0.0 0.1 5.0 3.1 7.9 15.2 0.0 0.4 0.1 2.5 0.0 2.1 0.2 0.0 2.5 5.2 21.8 4.1 4.5 17.8 216.4 2.3 0.0 14.4 1.5 2.7 0.8 0.0 17.7 1.7 0.7 0.0 0.1 4.2 0.1 0.0 4.7 9.1 0.4 1.2 0.0 0.4 0.0 8.6 0.1 0.0 0.0 ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.1;gallbladder: 16.6;intestine: 45.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 136.4;Oligodendrocyte precursor cells: 293.0;Oligodendrocytes: 419.4;Undifferentiated cells: 90.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 13.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034574 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA034574: AB_10669992" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.47e-4)" "unprognostic (3.99e-2)" "unprognostic (6.10e-3)" "unprognostic (4.69e-2)" "unprognostic (4.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-2)" "unprognostic (3.42e-2)" "unprognostic (5.12e-2)" "unprognostic (2.38e-3)" "unprognostic (5.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-1)" "unprognostic (2.14e-1)" 0.1 0.0 4.1 5.0 9.0 0.0 0.4 8.8 6.4 1.0 0.1 44.5 24.7 0.0 12.3 6.2 0.4 16.6 0.0 4.3 5.0 0.1 0.0 0.0 0.0 10.6 7.8 0.0 2.9 0.0 0.0 0.0 9.9 0.0 45.7 0.0 1.8 0.7 0.0 7.1 21.0 1.5 5.8 0.0 4.8 0.3 8.0 5.0 0.0 0.0 2.9 1.5 2.5 17.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.1 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 9.0 8.8 6.4 4.3 5.0 10.6 7.8 9.9 5.8 8.0 17.1 0.1 0.0 0.0 42.7 0.6 0.4 0.1 12.9 0.0 0.0 0.1 0.0 1.2 21.5 15.1 1.8 0.0 0.0 0.0 136.4 0.0 23.6 0.2 0.2 0.0 0.3 13.2 0.0 4.0 20.3 0.1 0.0 10.7 0.3 0.0 0.0 0.0 0.3 0.1 0.0 3.9 55.4 4.1 0.0 1.2 0.6 0.0 0.1 1.8 1.9 1.6 0.0 0.0 293.0 419.4 16.4 64.7 0.0 0.4 0.1 24.1 0.0 16.0 0.0 0.0 0.0 0.6 0.0 0.1 2.9 0.9 0.5 0.3 0.0 90.7 6.5 ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485275-47593486 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "basophil: 84.3" "Lineage enriched" "Detected in all" 12 "granulocytes: 84.3" "Cell line enhanced" "Detected in many" "HAP1: 41.6" "Low region specificity" "Detected in all" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Plasma membrane" "HPA050808: AB_2681242" "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.93e-2)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-2)" "unprognostic (8.05e-2)" "unprognostic (3.48e-2)" "unprognostic (3.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "prognostic favorable (5.00e-8)" "unprognostic (3.97e-2)" "unprognostic (4.47e-3)" "unprognostic (1.11e-2)" "unprognostic (3.37e-2)" 4.9 6.0 2.6 5.0 2.9 1.3 4.2 1.9 2.7 7.0 15.9 3.7 3.9 7.4 7.2 10.2 4.7 7.4 4.2 1.8 4.1 10.2 2.4 6.1 6.2 3.1 3.7 8.1 4.5 10.4 3.1 14.9 2.9 4.6 3.8 4.1 3.4 6.4 1.0 9.9 4.5 9.7 2.4 10.0 5.1 2.0 5.0 4.5 9.1 2.7 7.9 7.3 6.5 2.9 2.6 1.8 4.0 2.8 11.1 12.0 0.7 17.9 21.5 8.4 15.1 9.4 15.4 8.1 6.5 29.1 14.3 4.6 41.6 15.0 12.9 3.2 3.2 6.5 2.8 0.5 9.8 2.1 3.9 10.3 11.2 16.4 10.9 27.5 14.4 4.0 0.1 4.3 23.2 1.0 4.4 1.2 1.4 0.0 2.2 4.9 9.0 0.1 15.0 3.1 2.6 4.9 8.4 2.1 5.2 8.7 3.8 2.1 21.9 20.7 4.1 1.9 7.8 1.9 1.5 0.0 10.2 11.9 6.8 84.3 3.1 0.4 1.1 5.0 1.9 2.7 0.5 0.8 4.0 6.7 0.1 0.9 1.5 2.3 6.9 2.4 0.8 1.6 2.6 2.9 1.9 2.7 1.8 4.1 3.1 3.7 2.9 2.4 5.0 2.9 22.9 9.6 7.5 39.2 27.8 19.2 9.2 21.9 23.9 12.2 6.7 8.4 4.9 4.3 8.5 16.5 31.3 48.5 17.1 1.6 1.9 5.5 4.4 4.8 29.5 16.1 9.6 4.0 25.7 4.6 11.0 22.4 14.3 7.0 2.5 21.3 18.2 6.6 13.0 13.5 42.8 4.6 18.3 21.7 7.9 1.5 62.1 17.7 7.2 47.8 15.7 21.9 15.5 52.3 24.1 2.7 3.4 25.2 23.0 5.7 1.9 9.2 6.2 9.2 26.3 12.8 23.6 0.6 2.8 35.4 27.0 176.8 15.5 51.7 4.1 8.1 ATP11B "ATPIF, ATPIR, KIAA0956" ENSG00000058063 "ATPase phospholipid transporting 11B (putative)" Q9Y2G3 3 182793503-182921629 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 132.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036237, HPA036238" Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Centriolar satellite, Cytosol" "HPA036237: AB_10673123, HPA036238: AB_10670792" "unprognostic (4.52e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.50e-1)" "unprognostic (1.50e-1)" "unprognostic (6.73e-2)" "unprognostic (2.03e-3)" "unprognostic (7.28e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.09e-4)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (3.22e-1)" "unprognostic (8.66e-2)" "unprognostic (1.35e-1)" 20.6 10.7 4.7 24.9 6.9 70.6 17.4 15.9 7.6 19.1 13.8 26.3 24.3 18.7 14.6 45.4 13.7 21.1 14.1 6.0 6.3 18.0 18.3 16.5 27.9 7.5 6.1 20.5 21.0 29.4 10.3 14.5 7.3 28.3 29.0 30.8 19.4 13.4 11.4 28.2 24.0 19.5 5.6 21.8 51.1 31.6 6.6 44.6 16.8 16.8 28.4 25.7 22.5 15.8 69.7 9.7 20.5 28.7 42.6 46.1 19.3 32.8 41.6 23.2 27.1 23.7 34.0 31.3 53.5 44.0 48.2 40.4 24.6 31.3 40.2 73.9 20.9 76.7 13.1 5.2 24.8 62.3 47.3 31.5 34.7 26.1 37.4 34.1 37.0 48.7 27.7 94.3 37.8 22.9 50.3 19.1 14.5 38.1 19.2 21.2 59.8 37.8 28.1 55.8 12.5 22.0 86.2 10.7 36.9 18.3 11.9 43.7 36.6 35.0 38.7 30.5 56.2 131.0 125.5 58.1 24.1 25.3 20.9 5.5 1.0 4.3 1.7 1.0 1.7 2.1 1.4 1.7 1.1 1.3 1.2 1.8 3.8 1.8 1.0 2.4 1.2 0.8 4.7 6.9 15.9 7.6 6.0 6.3 7.5 6.1 7.3 5.6 6.6 15.8 26.8 16.0 13.2 34.6 27.8 34.3 25.7 15.9 26.2 12.2 13.8 9.7 15.6 18.6 16.5 20.2 14.6 12.8 43.0 44.6 0.0 12.5 34.1 19.0 22.9 15.7 6.7 26.1 81.6 16.5 3.8 19.5 46.4 22.1 11.4 14.0 16.1 16.4 10.4 38.7 64.3 30.5 16.2 19.4 26.4 23.8 19.3 29.3 14.2 45.9 19.9 8.4 27.8 67.8 132.6 25.2 27.0 21.1 55.5 35.8 24.3 7.8 19.8 31.4 19.7 24.1 17.7 18.7 11.4 43.8 44.6 9.6 40.9 7.0 27.3 45.4 ATP11C "ATPIG, ATPIQ" ENSG00000101974 "ATPase phospholipid transporting 11C" Q8NB49 X 139726346-139945276 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 49.8" "Cell type enhanced" "Detected in many" "Spermatocytes: 67.9" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030830 Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA030830: AB_10601336" "unprognostic (8.94e-2)" "unprognostic (1.00e-2)" "unprognostic (3.06e-2)" "unprognostic (3.42e-3)" "unprognostic (3.08e-1)" "unprognostic (3.46e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (4.80e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (3.65e-2)" "unprognostic (9.75e-2)" "unprognostic (2.73e-1)" "unprognostic (5.18e-2)" 13.4 7.4 3.5 9.0 4.2 6.1 10.4 3.6 4.6 11.8 10.3 10.0 5.6 11.9 9.3 5.1 10.7 8.4 5.4 3.1 4.5 11.8 49.8 7.2 14.8 4.9 4.7 12.7 4.9 5.7 3.7 5.3 5.2 9.8 7.1 2.8 6.0 14.6 3.5 6.0 8.6 10.6 3.9 12.2 7.6 9.7 4.8 11.1 6.1 4.3 8.8 13.6 9.3 4.5 16.9 7.1 14.2 23.3 20.7 27.9 18.0 19.7 26.4 15.6 21.5 6.3 13.4 24.0 43.3 28.2 10.3 13.7 34.6 9.0 24.4 22.1 20.2 12.1 15.2 12.3 23.0 21.4 7.4 18.6 5.9 16.9 14.4 17.3 27.3 18.3 14.0 17.9 20.8 9.1 19.7 14.5 24.1 0.1 13.3 19.5 15.3 20.1 13.1 27.6 11.0 18.3 7.8 0.8 10.6 13.3 5.8 11.7 31.0 21.2 6.9 25.9 27.1 5.1 5.4 18.7 9.7 26.3 10.8 2.4 0.4 0.1 0.4 0.3 0.8 0.9 0.4 0.3 0.4 0.9 0.4 0.7 0.9 1.2 0.6 0.7 0.3 0.2 3.5 4.2 3.6 4.6 3.1 4.5 4.9 4.7 5.2 3.9 4.8 4.5 27.4 16.0 8.4 22.5 14.6 14.5 16.7 6.5 5.7 1.9 8.0 8.9 4.4 2.8 9.2 11.0 0.0 2.3 11.6 7.0 1.9 4.8 13.6 11.5 22.7 32.4 9.1 15.3 1.3 10.1 12.6 17.2 10.7 13.7 9.5 23.6 34.6 46.6 9.4 0.0 26.1 6.4 8.2 37.2 14.4 11.9 14.3 15.3 10.6 45.9 33.9 3.1 7.2 29.1 27.8 7.8 7.2 15.4 13.2 15.8 4.7 7.7 6.8 3.1 0.0 19.3 19.2 67.9 53.1 5.9 13.5 6.7 12.7 11.5 5.2 14.6 ATP1B1 ATP1B ENSG00000143153 "ATPase Na+/K+ transporting subunit beta 1" P05026 1 169105697-169132722 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 1337.8" "Cell type enhanced" "Detected in all" "Collecting duct cells: 1723.3;Proximal tubular cells: 1070.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 919.7;RPTEC TERT1: 513.0;SH-SY5Y: 382.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012911 Enhanced NA NA 2100000 "Cluster 27: Non-specific - Gene expression" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA012911: AB_1845173" "unprognostic (4.20e-2)" "unprognostic (3.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.85e-2)" "unprognostic (1.95e-1)" "unprognostic (5.34e-2)" "unprognostic (2.22e-1)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (6.80e-2)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "prognostic favorable (7.08e-7)" "unprognostic (1.11e-1)" "unprognostic (5.48e-2)" "unprognostic (1.97e-3)" "unprognostic (9.39e-2)" 12.4 146.9 197.7 48.0 216.2 4.4 79.4 370.0 451.1 37.5 369.3 246.1 336.6 108.8 64.3 159.8 48.8 178.7 160.5 326.4 332.1 1337.8 180.1 92.6 8.5 558.7 264.3 58.1 178.5 732.7 79.8 44.1 540.2 48.6 201.1 99.3 314.1 72.6 342.9 67.0 284.4 96.6 248.8 52.6 402.1 46.3 375.1 19.2 330.2 337.8 84.0 101.2 52.1 382.2 89.7 215.8 73.3 56.3 15.9 3.3 23.8 45.3 33.1 41.7 43.3 276.8 183.5 0.1 158.3 35.1 50.8 102.4 38.1 83.2 45.1 1.1 16.6 5.7 152.6 138.9 26.6 4.0 7.5 9.1 21.1 31.8 42.5 79.7 40.5 6.6 1.3 1.4 52.6 38.0 7.9 16.0 28.1 919.7 47.4 1.3 89.3 15.6 513.0 118.6 54.3 382.5 263.1 271.3 12.5 85.4 55.7 9.8 92.0 35.2 90.4 60.9 159.3 4.8 6.8 2.0 42.0 13.9 47.9 13.2 1.0 0.2 2.7 3.2 1.5 1.5 3.3 1.3 9.3 0.2 1.0 1.1 0.3 6.2 1.1 0.4 10.1 1.4 197.7 216.2 370.0 451.1 326.4 332.1 558.7 264.3 540.2 248.8 375.1 382.2 14.4 240.4 251.5 79.0 18.4 52.5 156.5 490.4 153.1 86.9 274.2 166.5 147.3 664.8 425.7 1723.3 14.6 4.8 21.0 817.1 923.4 629.9 3.8 199.6 11.6 18.6 160.9 6.9 344.7 591.9 9.0 78.7 353.7 190.6 23.4 89.0 45.7 273.3 385.3 580.5 602.3 296.7 370.2 99.5 676.1 9.0 89.8 101.5 247.3 81.5 27.1 23.4 1.0 94.5 514.7 377.9 666.4 149.0 16.9 84.4 646.8 1070.2 332.5 64.9 6.6 93.6 32.5 10.6 66.9 142.8 31.7 9.9 48.2 111.8 436.0 322.8 ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 101.5;salivary gland: 185.3" "Cell type enhanced" "Detected in many" "B-cells: 82.5;Distal enterocytes: 120.7;Enteroendocrine cells: 97.8;Gastric mucus-secreting cells: 153.4;Intestinal goblet cells: 128.4;Plasma cells: 96.0;Undifferentiated cells: 65.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 186.8;HMC-1: 266.1;JURKAT: 152.1;MOLT-4: 253.2;SK-BR-3: 195.2" "Region enriched" "Detected in all" 15 "cerebellum: 67.2" "Low region specificity" "Detected in all" "HPA007180, CAB010882" Approved NA NA 5400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (4.14e-2)" "prognostic favorable (4.69e-5)" "unprognostic (1.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.02e-2)" "prognostic favorable (2.51e-4)" "unprognostic (8.83e-3)" "unprognostic (2.30e-1)" "unprognostic (8.29e-2)" "unprognostic (3.67e-3)" "unprognostic (3.95e-3)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (1.60e-1)" "unprognostic (3.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-3)" 6.8 13.7 6.8 62.2 8.7 98.3 7.7 20.0 6.1 6.0 15.3 55.0 30.7 9.1 1.6 9.7 6.1 13.7 8.0 3.0 4.5 11.4 4.6 22.4 101.5 2.3 12.8 3.1 64.0 2.1 2.5 2.8 3.9 20.3 33.0 0.2 185.3 19.6 3.3 28.2 75.3 6.3 2.0 98.2 92.8 2.1 11.6 97.5 11.7 3.3 58.7 17.0 7.2 2.3 0.3 7.6 0.3 6.8 0.0 0.0 0.3 0.4 0.9 0.2 0.6 2.5 1.7 186.8 11.0 0.6 0.1 0.8 3.1 0.0 0.0 23.5 2.1 98.0 6.0 0.1 1.7 108.0 266.1 0.2 0.0 0.7 0.0 0.1 0.3 152.1 20.1 117.1 0.1 116.8 253.2 115.5 1.2 53.1 1.6 27.5 0.2 43.3 0.0 3.3 11.5 3.4 1.5 195.2 0.2 1.1 12.2 26.3 0.5 0.0 2.1 0.4 0.1 43.4 14.2 66.0 2.5 75.6 0.1 16.0 1.4 33.7 10.8 0.9 8.3 9.8 6.7 10.3 1.6 11.4 4.8 6.0 13.1 3.8 0.5 15.8 6.4 6.7 6.8 8.7 20.0 6.1 3.0 4.5 2.3 12.8 3.9 2.0 11.6 2.3 7.1 0.0 1.9 0.7 82.5 0.9 0.4 0.7 1.2 0.0 4.7 1.7 3.8 2.8 2.7 23.9 0.0 0.2 59.2 120.7 0.0 1.3 0.1 0.3 0.4 7.8 97.8 22.5 0.5 12.1 0.3 1.9 153.4 0.3 33.0 0.2 8.9 1.0 2.8 0.0 0.6 128.4 36.7 3.1 2.5 0.2 0.0 17.8 12.4 5.6 5.0 0.2 28.8 0.0 0.3 25.2 50.3 0.7 96.0 4.2 14.0 0.4 2.7 0.2 0.0 1.0 3.4 0.0 1.5 0.4 0.3 0.0 38.4 0.4 65.6 4.6 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626787-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 175.3" "Cell type enhanced" "Detected in many" "Adipocytes: 171.6;Oligodendrocyte precursor cells: 199.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 200.0;BJ hTERT+: 276.4;fHDF/TERT166: 212.8;SuSa: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB016118: AB_2061729, HPA040431: AB_2676980" "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 58.9 25.0 39.7 25.6 36.3 16.0 16.6 0.0 33.5 47.5 0.3 58.2 12.5 104.5 20.1 32.5 48.4 25.2 59.5 40.2 13.3 9.9 9.3 35.1 12.8 8.0 8.0 40.6 9.9 11.8 3.8 40.6 11.2 33.0 30.2 42.5 7.1 69.7 14.4 54.8 14.4 175.3 0.2 12.2 15.4 27.4 44.7 21.7 15.1 27.7 19.4 37.2 15.3 2.6 45.7 7.8 15.6 15.1 120.4 175.1 84.5 200.0 276.4 32.1 27.4 3.8 22.8 9.8 28.8 212.8 43.5 43.5 22.6 27.7 34.3 126.5 8.0 28.7 37.4 2.5 43.1 42.0 51.3 130.5 26.9 102.9 16.2 81.6 63.5 57.1 12.9 20.3 25.1 2.5 44.3 14.5 9.7 8.7 24.2 22.3 11.6 16.7 11.3 4.0 4.6 6.7 68.3 10.5 30.2 222.1 9.3 21.4 54.9 80.5 11.4 136.6 48.3 13.4 20.9 5.4 80.7 31.0 24.5 3.2 2.0 0.0 8.7 1.3 6.4 0.9 5.4 7.2 2.2 0.3 1.3 3.4 4.0 3.8 2.2 3.7 5.7 2.7 39.7 36.3 0.0 33.5 40.2 13.3 8.0 8.0 11.2 0.2 44.7 2.6 171.6 89.8 68.2 127.6 9.9 97.1 18.9 43.1 41.5 4.8 11.2 9.4 76.5 7.2 35.0 18.4 2.1 27.9 56.2 2.2 0.0 35.3 5.8 78.0 92.4 67.6 23.9 35.9 55.9 14.9 18.9 56.0 13.7 89.7 10.1 30.6 58.9 18.2 38.5 117.8 9.8 2.4 14.2 14.7 38.8 4.8 43.8 20.4 26.6 37.5 18.1 136.1 66.9 199.0 40.4 31.4 11.1 38.0 27.6 48.2 7.2 3.3 39.7 7.8 19.7 50.7 81.2 21.7 2.8 54.7 150.9 26.0 59.7 8.0 3.3 62.0 ATP6V0A4 "a4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, Stv1, Vph1, VPP2" ENSG00000105929 "ATPase H+ transporting V0 subunit a4" Q9HBG4 7 138706294-138799560 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "kidney: 63.6;salivary gland: 78.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 16.5;Cytotrophoblasts: 13.4;Distal tubular cells: 31.3;Ionocytes: 57.0" "Cancer enriched" "Detected in many" 8 "renal cancer: 25.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SK-BR-3: 55.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018029, HPA064555" Enhanced Uncertain Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA018029: AB_1845190, HPA064555: AB_2685284" "unprognostic (1.99e-2)" "unprognostic (8.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.10e-2)" "unprognostic (1.43e-1)" "unprognostic (6.53e-2)" "unprognostic (4.63e-2)" "unprognostic (4.28e-1)" "unprognostic (1.35e-1)" "unprognostic (9.79e-3)" "unprognostic (1.73e-1)" "prognostic favorable (1.32e-6)" "unprognostic (4.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-1)" "unprognostic (1.10e-2)" 0.2 0.0 0.3 0.0 0.4 0.0 4.7 0.1 0.5 3.7 3.1 0.0 0.1 0.1 1.2 4.9 0.0 0.0 0.0 0.6 0.2 63.6 0.0 0.4 0.0 0.3 0.2 0.0 0.1 1.6 0.1 2.5 0.2 0.9 0.0 0.0 78.4 1.5 0.0 10.2 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.4 0.0 0.0 3.7 0.1 0.2 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.6 0.6 1.8 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 5.0 1.9 0.0 0.1 0.0 0.1 0.1 0.6 0.0 4.5 0.2 0.0 0.0 0.1 55.7 1.9 2.9 0.1 0.0 0.2 0.6 1.3 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.1 0.5 0.6 0.2 0.3 0.2 0.2 0.2 0.3 0.3 0.0 0.0 1.1 0.3 0.0 0.0 1.1 0.9 0.0 0.0 2.5 1.4 0.5 0.0 1.7 16.5 2.1 13.4 0.3 0.0 31.3 0.0 2.2 0.9 0.1 0.1 0.0 0.0 1.4 0.0 0.7 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 57.0 0.0 0.0 2.8 0.3 0.0 7.2 1.0 0.0 0.0 0.0 6.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 4.4 0.1 0.0 0.0 0.1 0.6 0.7 0.0 0.1 5.1 0.2 0.0 0.0 1.3 ATP6V1B1 "ATP6B1, RTA1B, VATB, Vma2, VPP3" ENSG00000116039 "ATPase H+ transporting V1 subunit B1" P15313 2 70935900-70965431 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 127.4;salivary gland: 139.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 197.3;Distal tubular cells: 49.0;Ionocytes: 321.4;Syncytiotrophoblasts: 64.9" "Group enriched" "Detected in many" 5 "ovarian cancer: 94.7;renal cancer: 23.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BEWO: 21.6;HaCaT: 20.3;SK-BR-3: 49.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009523, HPA031847" Enhanced Approved "Nucleoplasm,Nuclear membrane" No NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear membrane" "CAB009523: AB_677577, HPA031847: AB_2674072" "unprognostic (2.28e-2)" "unprognostic (6.02e-2)" "unprognostic (2.20e-5)" "unprognostic (1.15e-2)" "unprognostic (3.96e-1)" "unprognostic (1.31e-1)" "unprognostic (2.22e-2)" "unprognostic (2.17e-1)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (2.94e-2)" "unprognostic (1.40e-1)" "unprognostic (1.33e-3)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (3.63e-5)" "unprognostic (1.97e-2)" 2.2 0.5 0.5 0.2 0.3 0.0 11.8 0.7 0.9 31.1 0.0 0.6 0.5 1.4 1.2 1.6 12.8 0.2 1.1 0.2 0.0 127.4 0.2 1.7 0.5 0.1 0.0 1.2 3.3 0.8 4.2 17.9 0.1 2.0 0.1 3.9 139.8 1.4 0.5 32.5 0.6 0.8 0.0 0.0 0.3 0.3 0.0 0.1 0.3 0.2 0.0 0.6 0.8 0.3 0.4 0.3 0.6 1.3 2.6 3.1 21.6 0.4 0.2 0.0 0.0 0.1 2.0 0.1 0.2 1.2 0.0 20.3 0.7 0.0 0.0 0.5 0.6 0.0 0.3 0.3 0.0 0.0 0.0 1.5 0.1 0.0 0.3 3.1 0.0 0.1 0.0 0.0 0.2 1.2 0.1 0.3 0.0 0.0 0.0 0.1 0.8 0.2 0.4 0.2 0.5 1.5 0.7 49.2 0.1 2.7 0.6 0.0 0.4 0.6 0.2 0.9 0.5 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.7 0.9 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.7 3.2 0.0 0.3 0.0 0.1 1.3 1.7 0.0 0.9 5.6 3.7 0.4 0.0 13.9 0.0 8.4 197.3 0.1 0.6 49.0 0.1 1.5 0.0 0.1 1.1 0.0 0.0 1.0 0.6 38.3 3.8 0.0 0.1 0.0 0.0 0.0 0.1 11.7 1.7 0.4 0.0 321.4 0.0 0.3 0.1 0.0 0.1 30.2 0.0 0.0 0.5 1.0 1.0 0.1 0.4 0.0 1.2 0.0 0.6 0.3 0.2 2.6 3.8 0.0 1.1 1.0 0.4 1.2 0.0 0.4 64.9 0.1 0.1 0.1 0.6 ATP6V1F "ATP6S14, VATF, Vma7" ENSG00000128524 "ATPase H+ transporting V1 subunit F" Q16864 7 128862856-128865847 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1054.6;Hofbauer cells: 1132.8;Proximal tubular cells: 1076.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009529, HPA048700, HPA062011" Supported NA NA 26000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" "CAB009529: AB_2290237, HPA048700: AB_2680498, HPA062011: AB_2684656" "unprognostic (1.70e-1)" "unprognostic (1.61e-2)" "unprognostic (2.14e-2)" "unprognostic (3.26e-2)" "unprognostic (2.99e-2)" "unprognostic (8.46e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.28e-3)" "unprognostic (2.70e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "prognostic favorable (2.49e-5)" "unprognostic (2.20e-1)" "unprognostic (2.43e-1)" "unprognostic (1.36e-2)" "unprognostic (7.33e-2)" 133.3 160.7 275.6 106.2 290.1 210.4 122.3 272.7 368.6 126.5 250.2 104.6 74.7 95.3 61.7 223.0 98.3 104.2 183.3 294.8 300.1 307.0 84.2 140.0 139.9 280.1 275.3 89.0 106.8 163.5 141.0 104.6 286.0 103.0 56.6 110.6 129.3 81.6 169.3 170.1 97.0 71.2 269.5 119.6 114.4 212.2 284.3 119.6 84.6 154.7 103.7 123.1 146.6 277.4 305.6 345.1 151.2 323.2 297.6 236.8 86.9 151.2 201.3 246.8 267.2 257.0 179.8 287.6 156.5 175.7 367.7 163.9 224.5 250.1 91.9 312.6 364.2 220.1 211.4 256.4 344.1 227.1 400.8 278.2 340.0 284.7 163.4 188.9 238.1 257.9 534.3 297.3 276.3 403.1 381.0 494.3 201.9 190.6 281.4 168.7 110.1 467.5 315.5 240.3 286.6 197.3 214.1 796.5 363.7 156.6 184.4 284.9 253.0 303.5 65.3 409.5 236.2 333.5 326.9 372.0 600.4 315.5 263.6 370.2 697.1 489.2 244.6 475.1 238.0 343.7 247.6 239.7 508.9 348.5 235.8 238.6 203.1 243.6 324.7 288.3 317.3 886.1 275.6 290.1 272.7 368.6 294.8 300.1 280.1 275.3 286.0 269.5 284.3 277.4 129.3 28.9 62.8 17.3 140.1 237.6 202.5 378.9 136.6 111.4 162.0 190.1 157.6 127.2 230.7 331.1 37.5 171.8 119.8 97.3 1054.6 241.0 574.0 128.6 96.3 163.1 113.2 63.1 27.0 222.2 289.0 155.1 78.5 131.0 275.1 114.0 124.6 112.0 1132.8 545.1 34.6 108.7 585.9 320.6 378.7 898.9 164.4 456.1 254.3 16.9 285.8 230.4 190.5 11.6 26.2 253.9 93.0 127.9 136.8 224.7 212.0 1076.3 200.2 96.4 85.5 69.7 168.9 399.6 102.0 328.4 326.6 401.4 136.3 184.5 98.9 362.7 ATP7A MNK ENSG00000165240 "ATPase copper transporting alpha" Q04656 X 77910656-78050395 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 61.1;Microglial cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012887, HPA048107" Approved Supported "Golgi apparatus" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA012887: AB_1845205, HPA048107: AB_2680266" "unprognostic (3.14e-2)" "unprognostic (3.48e-1)" "unprognostic (4.90e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-3)" "unprognostic (2.59e-2)" "unprognostic (3.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.30e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.38e-4)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (3.69e-1)" "unprognostic (2.52e-1)" 3.0 4.3 1.2 3.6 1.7 5.9 6.3 2.3 2.1 3.9 1.6 3.4 3.9 3.6 5.0 4.9 3.5 3.6 2.5 1.3 2.1 4.4 2.3 4.5 4.1 2.1 2.1 3.6 2.4 7.3 2.5 4.0 3.8 5.3 3.4 3.0 5.1 3.4 1.8 11.1 3.4 3.2 1.1 4.7 5.5 1.6 1.6 4.7 4.6 2.9 4.6 3.9 2.8 2.9 3.2 8.3 5.4 5.5 5.0 5.3 0.9 4.8 6.6 2.8 5.7 1.0 3.6 4.7 6.9 4.8 3.3 3.8 7.1 3.9 5.2 7.0 4.8 2.4 7.8 0.8 6.3 4.1 4.1 5.6 1.6 5.9 1.8 6.5 7.3 4.7 19.6 17.4 5.2 2.8 4.6 1.4 1.5 11.2 1.7 3.7 9.0 15.8 4.6 8.8 1.6 20.4 11.9 2.8 6.0 3.3 2.2 1.3 9.4 3.7 3.6 5.2 1.9 5.6 10.7 5.2 6.0 2.5 5.7 7.1 1.5 4.5 1.8 1.5 0.9 1.8 1.2 1.2 1.0 1.4 1.4 2.1 8.1 1.2 1.9 1.0 0.4 1.0 1.2 1.7 2.3 2.1 1.3 2.1 2.1 2.1 3.8 1.1 1.6 2.9 14.3 0.0 8.4 15.7 12.6 7.4 5.1 5.8 13.1 6.4 17.3 10.0 5.1 1.5 8.2 9.2 4.2 2.0 15.0 4.5 1.9 5.6 0.5 5.3 9.2 9.7 4.8 22.5 11.1 13.6 2.2 9.4 20.4 8.8 9.5 6.4 14.6 3.6 14.3 1.7 12.5 4.8 61.1 11.7 6.7 1.1 7.2 12.6 19.6 44.0 5.5 4.4 11.3 37.7 35.0 6.2 4.1 9.8 10.5 4.8 4.1 5.5 10.2 4.1 32.9 10.3 8.7 1.8 5.4 20.5 16.6 2.2 13.8 6.7 5.2 6.6 ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25371974-26025851 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 21.6;pituitary gland: 15.2;retina: 17.2" "Group enriched" "Detected in many" 6 "Excitatory neurons: 518.7;Inhibitory neurons: 727.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 19.9;JURKAT: 9.8;MOLT-4: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: AB_2676809" "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" 0.1 2.1 5.5 0.3 6.7 0.0 0.6 8.0 21.6 0.2 0.0 0.4 0.3 0.6 1.8 0.0 0.0 0.1 0.1 8.7 19.3 0.3 0.0 0.8 0.6 12.8 4.6 0.2 0.6 0.0 15.2 0.2 12.1 0.1 0.2 17.2 0.1 0.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 2.9 6.6 1.0 0.1 0.1 0.2 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 19.9 0.1 0.0 0.0 0.0 0.6 0.5 9.8 0.0 0.0 1.7 0.1 3.9 0.0 2.0 0.0 0.7 0.0 2.7 0.9 0.2 0.0 3.2 0.0 0.2 0.2 0.1 0.2 0.0 0.4 0.2 0.0 1.0 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.2 0.1 5.5 6.7 8.0 21.6 8.7 19.3 12.8 4.6 12.1 0.2 6.6 6.8 0.7 0.0 12.2 9.4 0.8 1.0 0.2 0.3 0.0 21.5 1.5 0.3 2.5 1.5 0.4 0.0 95.9 1.5 0.4 0.0 0.0 0.3 39.0 1.2 23.6 2.6 0.0 0.8 518.7 0.0 0.4 1.7 1.1 0.9 5.1 3.7 0.0 0.0 3.2 21.9 727.7 0.0 0.0 0.0 0.7 30.3 0.9 0.3 0.0 9.4 0.0 7.2 1.0 88.4 24.7 0.0 0.0 1.2 0.1 0.2 0.0 1.3 0.3 91.6 13.1 0.3 0.8 19.8 12.5 0.0 0.4 1.1 1.8 10.1 0.1 0.1 ATP8B4 "ATPIM, KIAA1939" ENSG00000104043 "ATPase phospholipid transporting 8B4 (putative)" Q8TF62 15 49858238-50182817 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "bone marrow: 78.1" "Cell type enriched" "Detected in many" 6 "Microglial cells: 248.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.2;NK-cell: 11.0" "Group enriched" "Detected in many" 5 "granulocytes: 15.2;NK-cells: 11.0" "Cell line enhanced" "Detected in some" "HMC-1: 40.2;NB-4: 19.2;THP-1: 26.7;U-937: 103.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040254 Approved Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" Cytosol "HPA040254: AB_10673028" "unprognostic (6.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.39e-2)" "unprognostic (2.96e-3)" "unprognostic (3.25e-1)" "unprognostic (6.51e-3)" "unprognostic (1.03e-1)" "unprognostic (4.87e-3)" "unprognostic (1.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.20e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" 1.4 1.1 2.3 2.5 2.4 78.1 0.7 3.5 6.5 1.5 3.0 1.1 0.7 6.4 4.2 0.5 3.1 2.2 0.4 4.5 2.9 1.2 1.6 1.1 1.0 2.5 2.6 0.4 0.5 0.2 0.3 3.5 2.8 0.6 1.7 0.1 0.5 0.8 0.1 0.3 1.3 3.1 3.1 2.6 0.6 0.4 2.4 0.5 0.1 0.1 1.0 1.4 0.4 4.9 0.1 0.6 0.0 0.0 0.0 0.7 0.2 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.5 0.5 0.2 0.0 0.2 12.2 0.0 7.3 1.7 0.1 0.0 13.6 40.2 0.7 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 19.2 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.1 1.5 0.1 1.2 0.0 0.0 0.1 0.0 26.7 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.0 1.3 103.7 0.0 15.2 2.0 3.8 0.4 1.2 0.1 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.8 11.0 0.4 0.0 0.0 0.9 2.3 2.4 3.5 6.5 4.5 2.9 2.5 2.6 2.8 3.1 2.4 4.9 1.7 0.0 1.9 1.6 0.8 1.5 0.1 0.2 0.6 0.6 0.2 0.6 1.3 0.0 0.1 0.0 0.0 5.4 12.5 0.3 0.0 0.0 27.6 0.3 1.7 1.0 0.0 12.2 20.3 0.0 1.8 8.1 3.1 0.2 19.7 0.0 1.1 3.7 16.4 0.0 17.5 0.3 2.0 37.0 17.7 25.3 1.8 27.0 1.8 248.3 6.3 0.5 15.5 1.0 2.1 0.0 0.1 0.7 4.8 2.3 0.7 1.2 0.7 0.2 0.0 1.0 7.0 0.5 0.6 0.6 0.3 2.9 13.4 1.1 0.2 0.3 ATPAF2 "ATP12, Atp12p, LP3663, MGC29736" ENSG00000171953 "ATP synthase mitochondrial F1 complex assembly factor 2" Q8N5M1 17 17977409-18039209 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 104.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023329, HPA059422" Supported Enhanced Cytosol No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA023329: AB_1845209, HPA059422: AB_2684011" "unprognostic (3.16e-2)" "unprognostic (1.98e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.95e-4)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (2.70e-3)" "unprognostic (1.67e-2)" "prognostic favorable (6.00e-5)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (5.15e-1)" "unprognostic (2.62e-2)" 8.6 18.5 7.4 8.6 7.6 15.9 8.7 8.3 11.1 8.4 8.3 11.1 8.7 6.8 8.7 14.4 8.1 4.9 23.9 7.5 9.1 16.1 19.7 7.8 10.5 7.9 8.1 7.3 9.8 26.3 9.3 7.7 8.4 9.1 10.4 6.4 10.7 6.6 24.7 14.6 10.2 8.4 7.8 10.4 12.0 10.9 7.8 10.8 10.6 27.8 14.5 9.1 9.5 8.4 13.0 24.1 15.4 14.7 15.1 16.2 15.6 11.2 16.4 23.7 20.1 31.8 19.3 26.0 24.6 19.5 13.1 19.9 14.8 24.1 20.7 20.9 11.7 5.8 14.8 18.6 25.5 8.2 17.3 19.5 16.8 21.4 11.9 16.7 27.4 21.3 9.3 8.9 13.1 26.8 19.4 12.8 10.4 48.3 13.3 19.8 27.1 29.9 19.0 11.4 9.9 13.5 14.9 7.6 14.0 104.2 24.4 16.2 11.6 6.0 12.4 22.2 10.9 6.2 8.4 9.6 10.7 11.9 31.4 7.8 41.5 14.7 9.3 28.6 10.4 27.9 6.9 8.9 49.2 19.7 10.7 8.0 3.0 8.9 22.3 41.6 12.9 20.7 7.4 7.6 8.3 11.1 7.5 9.1 7.9 8.1 8.4 7.8 7.8 8.4 8.8 6.4 7.8 9.4 20.3 15.3 12.0 23.7 9.6 10.5 13.9 10.8 28.2 20.0 14.4 12.9 33.3 32.5 20.7 10.9 66.5 19.3 52.9 10.5 6.0 10.0 14.5 13.7 13.7 12.3 30.9 9.1 8.2 8.5 13.3 25.7 9.3 20.8 45.5 10.1 14.1 18.2 16.2 22.3 22.5 42.6 6.5 18.2 17.8 7.5 28.1 13.8 13.4 9.0 9.6 16.0 24.4 6.8 18.6 13.8 25.8 58.8 17.2 17.7 0.0 8.4 10.4 28.2 20.9 17.6 18.9 28.7 9.0 15.9 20.5 12.3 ATXN7 "ADCAII, OPCA3, SCA7, SGF73" ENSG00000163635 "Ataxin 7" O15265 3 63863155-64003462 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 15.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034989 Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA034989: AB_10602596" "unprognostic (1.51e-2)" "unprognostic (2.44e-1)" "unprognostic (5.98e-2)" "unprognostic (2.18e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.22e-4)" "unprognostic (9.65e-2)" "unprognostic (2.76e-2)" "unprognostic (2.46e-1)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "unprognostic (9.77e-3)" "unprognostic (2.56e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (3.45e-2)" 7.5 6.3 4.5 11.4 4.1 24.4 7.1 4.9 4.4 7.4 0.2 6.9 8.0 8.6 4.7 8.7 6.3 9.6 5.8 3.1 3.7 7.1 8.4 9.0 12.7 3.4 3.3 8.0 21.0 10.9 2.3 8.3 2.7 6.7 8.8 16.3 7.8 5.2 7.1 9.3 9.2 7.9 0.7 10.6 8.4 15.0 3.1 16.5 7.5 8.7 11.7 7.4 4.4 3.2 8.4 5.7 8.1 7.2 8.5 11.3 9.5 6.5 9.0 11.1 10.5 8.9 8.7 12.5 3.1 9.0 12.5 6.5 9.6 9.1 11.9 22.8 4.9 16.1 10.7 4.2 6.4 8.5 17.7 7.9 9.0 15.7 17.7 9.0 8.4 13.3 6.3 26.2 7.7 25.8 12.7 6.8 5.5 5.7 3.0 9.1 7.1 10.1 6.1 11.0 3.1 5.6 13.2 9.4 10.8 6.4 5.1 12.2 11.9 11.4 12.0 12.7 12.9 12.9 13.2 10.3 10.3 11.6 9.4 15.8 1.1 2.1 3.7 1.0 3.3 1.0 6.2 4.0 0.8 2.4 6.2 4.1 4.5 3.5 0.7 1.5 6.2 1.3 4.5 4.1 4.9 4.4 3.1 3.7 3.4 3.3 2.7 0.7 3.1 3.2 2.4 9.6 9.1 34.6 17.0 43.6 24.9 17.6 29.6 73.2 3.4 1.7 10.5 35.8 17.9 5.5 102.2 14.1 21.5 38.3 0.0 2.8 17.1 3.3 1.5 16.1 26.4 29.5 81.2 4.2 13.6 16.6 18.8 3.5 14.7 1.2 26.7 22.8 14.2 25.2 67.0 19.7 24.4 34.6 30.3 9.5 12.8 20.1 12.4 64.6 33.5 24.5 54.6 60.3 46.7 2.5 28.5 13.2 14.8 26.1 28.1 0.7 27.4 70.8 0.0 39.2 15.6 14.8 15.6 25.6 46.2 61.2 41.5 1.6 20.1 38.6 AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.1;testis: 30.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.6;Extravillous trophoblasts: 67.1;granulocytes: 54.1;Spermatocytes: 168.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB001454, HPA002636" Enhanced Approved "Nucleoplasm,Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 7: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "Mitotic spindle, Cytosol" "CAB001454: AB_563420, HPA002636: AB_1845217" "unprognostic (7.73e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (9.40e-5)" "unprognostic (1.92e-1)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.69e-3)" "unprognostic (2.42e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.47e-8)" "unprognostic (1.67e-1)" "unprognostic (6.83e-2)" "unprognostic (9.00e-2)" "unprognostic (5.14e-2)" 1.3 2.3 1.3 10.4 1.6 15.3 2.2 2.4 1.4 1.4 0.6 10.8 11.7 1.5 0.8 7.5 1.2 2.0 5.3 0.8 1.0 2.3 5.0 2.2 20.9 1.7 1.2 8.4 2.0 1.8 0.6 8.1 1.4 1.1 12.9 3.0 1.9 1.3 8.7 3.5 9.3 4.9 1.3 5.2 4.9 30.8 1.6 20.2 1.4 8.2 22.1 2.9 2.6 1.3 179.9 127.2 84.5 61.2 4.9 10.8 106.3 145.2 66.8 339.7 142.9 361.4 124.8 58.4 96.2 59.2 176.2 142.2 152.4 96.4 360.0 52.4 57.5 102.6 128.9 229.8 2.8 140.4 140.4 5.1 10.1 117.3 104.5 26.7 80.7 93.2 121.8 45.3 146.9 182.1 85.3 108.9 78.3 145.6 129.8 62.9 163.4 65.9 56.0 46.8 73.9 39.6 200.5 228.8 94.2 77.3 137.9 86.1 47.1 149.7 145.3 83.0 208.6 62.3 78.9 100.5 80.5 80.9 127.0 0.2 3.5 4.3 1.2 5.9 1.8 2.5 2.0 1.1 3.7 0.8 0.9 0.9 2.3 1.4 3.4 0.8 4.7 1.7 1.3 1.6 2.4 1.4 0.8 1.0 1.7 1.2 1.4 1.3 1.6 1.3 2.5 0.0 2.8 0.3 7.4 1.1 1.2 5.6 0.6 1.0 4.3 6.2 5.6 1.5 2.3 3.7 2.1 34.5 8.3 8.3 1.9 4.0 33.9 2.0 2.3 3.1 6.0 81.6 1.1 4.9 67.1 7.0 13.7 3.4 54.1 12.3 3.6 2.6 17.5 1.7 1.5 10.8 2.0 3.5 7.6 16.3 1.5 11.7 0.0 1.0 12.0 3.7 3.1 1.0 2.0 5.2 2.8 0.4 10.1 2.0 5.1 4.2 1.5 2.7 6.6 2.2 7.7 168.2 30.8 8.3 1.1 8.2 8.0 8.7 15.5 1.5 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.1;lymphoid tissue: 60.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Erythroid cells: 59.3;Extravillous trophoblasts: 89.1;Granulosa cells: 24.7;Hofbauer cells: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.1 1.2 0.1 14.2 0.2 44.1 1.7 0.2 0.2 3.0 0.1 11.1 12.1 1.6 0.4 18.6 0.6 1.5 0.7 0.1 0.2 0.9 2.0 2.5 36.7 0.1 0.3 0.5 0.6 0.3 0.2 8.2 0.3 0.8 11.0 0.0 2.7 0.3 5.5 9.3 11.6 3.2 0.0 12.0 4.6 1.2 0.4 60.1 0.6 0.0 36.6 3.5 5.9 0.2 196.5 130.9 191.1 93.0 4.2 6.5 73.4 91.7 49.5 186.2 170.6 171.5 57.4 193.3 46.2 37.0 77.0 139.8 140.1 62.6 153.7 84.9 231.3 115.7 78.3 146.1 0.7 62.2 109.2 3.5 2.9 109.4 67.7 18.5 86.5 123.6 73.3 73.4 82.9 92.9 225.1 87.4 119.6 63.9 57.6 149.8 176.1 80.5 41.2 38.2 41.2 59.1 81.7 36.5 61.2 56.5 63.5 41.4 33.9 74.3 75.6 67.6 243.3 53.2 37.7 147.9 35.7 92.9 153.4 0.0 0.4 0.6 0.5 0.3 0.1 1.1 1.3 2.1 0.5 2.5 0.1 0.7 0.9 0.3 0.2 0.2 7.9 0.9 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.4 0.2 0.3 0.0 0.5 0.0 7.6 4.5 1.8 6.1 0.6 0.0 1.8 2.2 1.4 0.0 2.6 0.0 0.0 40.5 1.8 13.2 0.0 0.4 0.1 0.5 1.6 3.1 0.0 59.3 0.0 0.0 89.1 5.7 6.1 2.1 4.5 24.7 6.1 0.7 29.4 0.0 0.0 10.8 0.0 5.7 7.3 0.2 0.6 5.1 1.8 0.0 0.9 0.0 3.1 0.0 0.1 0.3 2.8 0.0 15.4 1.2 1.5 0.1 0.2 0.0 0.0 0.1 4.8 1.6 7.2 11.8 2.4 9.0 4.3 1.0 22.0 2.8 AVEN PDCD12 ENSG00000169857 "Apoptosis and caspase activation inhibitor" Q9NQS1 15 33858782-34075155 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 44.0;Oligodendrocytes: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020863 Approved Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Actin filaments" Centrosome "HPA020863: AB_1845219" "unprognostic (1.54e-3)" "unprognostic (1.99e-1)" "unprognostic (8.93e-2)" "unprognostic (5.77e-2)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (6.32e-3)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (4.14e-3)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.29e-10)" "unprognostic (7.66e-3)" "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (2.84e-3)" 13.7 11.4 8.5 7.2 8.6 4.4 10.8 8.9 10.1 11.4 10.5 15.2 7.4 12.5 5.2 12.3 11.3 6.4 28.5 8.2 9.2 5.5 16.9 7.2 4.8 9.2 9.0 10.5 20.8 3.0 5.8 12.4 9.4 9.4 9.4 2.5 7.9 9.1 31.1 11.2 7.5 12.5 8.8 6.5 12.3 10.7 9.0 6.9 5.6 13.6 7.9 16.2 10.8 9.1 16.4 26.3 26.0 8.6 21.4 24.1 14.7 41.1 36.2 31.9 19.9 7.2 11.3 15.2 24.8 34.8 24.2 10.4 12.2 26.9 25.7 14.6 7.7 26.1 15.9 20.5 31.5 26.6 18.2 19.8 50.9 18.4 45.8 38.6 35.2 7.6 26.6 21.1 45.6 17.3 10.5 46.1 11.9 22.2 8.5 15.7 14.6 32.2 26.4 21.0 13.4 16.8 22.6 11.6 11.4 10.7 12.6 29.4 24.5 27.7 9.5 12.0 34.6 21.2 17.7 31.1 13.3 31.0 15.2 0.0 0.2 0.0 0.5 0.6 0.6 0.4 0.5 0.2 0.2 0.1 0.2 0.3 0.0 0.5 0.2 2.3 0.9 0.1 8.5 8.6 8.9 10.1 8.2 9.2 9.2 9.0 9.4 8.8 9.0 9.1 9.0 3.2 5.3 16.6 5.6 5.7 8.7 1.8 3.4 5.6 7.5 9.0 32.7 2.8 0.8 0.0 6.2 11.0 10.5 7.4 0.0 2.9 13.8 4.4 14.3 10.2 4.8 9.5 21.8 8.6 44.0 8.5 5.6 5.6 0.0 14.7 8.6 19.1 7.4 8.4 24.1 7.7 0.0 4.1 4.4 6.5 7.5 5.0 3.6 22.5 3.5 10.9 7.2 26.7 86.6 7.0 5.2 10.5 15.6 21.5 9.4 4.6 1.5 5.3 6.6 4.9 9.7 6.2 7.4 12.9 9.7 9.4 6.5 23.1 6.0 14.7 AWAT1 DGAT2L3 ENSG00000204195 "Acyl-CoA wax alcohol acyltransferase 1" Q58HT5 X 70234655-70240659 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA063412 Enhanced NA NA "Cluster 61: Skin - Cornification" "HPA063412: AB_2685009" "unprognostic (1.12e-1)" "unprognostic (1.78e-1)" "unprognostic (1.96e-2)" "unprognostic (4.90e-2)" "unprognostic (2.08e-1)" "unprognostic (6.78e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AWAT2 "DGAT2L4, MFAT" ENSG00000147160 "Acyl-CoA wax alcohol acyltransferase 2" Q6E213 X 70040542-70049938 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 11.2" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 8.3" "Cancer enriched" "Detected in single" 7 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062748 Approved NA NA "Cluster 61: Skin - Cornification" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA062748: AB_2684862" "unprognostic (3.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.99e-2)" "unprognostic (4.11e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (4.55e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 8.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 AXDND1 "C1orf125, FLJ32940" ENSG00000162779 "Axonemal dynein light chain domain containing 1" Q5T1B0 1 179365720-179554735 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 15.7" "Group enriched" "Detected in some" 4 "Early spermatids: 226.5;Late spermatids: 247.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA071114 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA071114: AB_2686345" "unprognostic (1.67e-2)" "unprognostic (8.37e-2)" "unprognostic (2.81e-2)" "unprognostic (1.05e-1)" "unprognostic (3.34e-1)" "unprognostic (1.73e-1)" "unprognostic (3.78e-4)" "unprognostic (2.62e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-3)" "unprognostic (2.09e-2)" "unprognostic (1.31e-1)" "unprognostic (5.17e-3)" "unprognostic (1.92e-1)" "unprognostic (5.48e-2)" "unprognostic (5.04e-2)" "unprognostic (2.25e-1)" 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.2 15.7 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.4 0.2 0.3 0.2 0.2 0.1 0.0 0.5 8.8 0.3 0.0 0.1 0.1 0.0 0.3 0.1 0.3 0.8 0.0 0.8 0.0 2.1 0.1 0.1 16.3 0.0 0.2 226.5 3.1 0.3 0.2 0.0 0.0 3.1 0.2 0.3 0.1 31.6 0.3 0.0 0.2 0.0 0.0 0.1 0.0 3.2 1.5 0.0 0.0 0.0 247.2 1.5 0.5 0.0 1.0 0.0 0.6 0.0 2.0 2.5 0.6 3.8 1.9 0.1 0.1 2.0 0.1 3.2 0.7 0.0 0.0 0.2 50.2 4.3 0.0 0.0 0.1 0.2 0.6 6.1 0.2 B3GALT1 beta3Gal-T1 ENSG00000172318 "Beta-1,3-galactosyltransferase 1" Q9Y5Z6 2 167868948-167874041 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;skeletal muscle: 5.2;tongue: 17.8" "Group enriched" "Detected in some" 6 "Astrocytes: 920.7;Excitatory neurons: 519.3;Inhibitory neurons: 723.8" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "AN3-CA: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.22e-2)" "unprognostic (1.67e-1)" "unprognostic (4.23e-3)" "unprognostic (2.49e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-1)" "unprognostic (3.94e-2)" "unprognostic (8.72e-2)" "unprognostic (6.44e-2)" "unprognostic (2.30e-3)" "unprognostic (8.34e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (3.79e-1)" 0.2 0.5 4.0 0.2 5.4 0.1 0.4 2.0 5.8 0.3 0.0 3.6 0.0 0.2 0.4 0.1 0.6 0.0 0.0 5.8 3.0 0.1 0.0 0.1 0.0 2.4 2.9 0.2 0.3 0.0 1.8 0.0 1.4 0.2 3.6 2.4 0.2 0.7 5.2 0.2 0.2 0.2 2.0 0.2 0.0 0.5 2.6 0.0 0.2 17.8 0.0 0.0 0.2 3.4 0.0 0.0 2.8 35.7 0.3 0.0 0.0 0.5 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 4.6 0.0 1.2 0.0 0.2 0.0 0.5 0.0 2.3 0.4 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.0 0.8 0.0 0.7 0.0 3.3 0.5 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.3 0.2 0.2 0.1 0.0 0.1 0.1 0.0 4.0 5.4 2.0 5.8 5.8 3.0 2.4 2.9 1.4 2.0 2.6 3.4 0.2 0.0 1.3 920.7 0.2 0.1 0.0 0.0 0.0 3.0 0.1 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.1 18.3 0.0 0.1 0.5 0.1 0.6 0.7 0.0 0.0 519.3 0.2 0.0 0.5 0.0 0.4 1.3 0.0 0.0 0.0 0.1 1.7 723.8 3.8 0.0 0.0 0.3 0.0 0.6 0.3 1.8 39.4 0.0 2.4 0.0 108.0 30.3 0.0 3.4 1.5 0.0 0.4 0.0 0.4 0.0 1.3 0.0 1.1 0.6 0.0 1.7 0.0 0.0 0.0 0.1 0.1 7.4 0.1 B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 196.4;Intestinal goblet cells: 47.4;Paneth cells: 72.5;Proximal enterocytes: 94.1;Undifferentiated cells: 57.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 23.5;RPTEC TERT1: 27.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.6" "HPA054092, HPA054684" Approved "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA054092: AB_2682375, HPA054684: AB_2682573" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "prognostic favorable (6.36e-4)" "unprognostic (9.23e-2)" "unprognostic (4.62e-2)" "unprognostic (4.06e-2)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.86e-3)" "unprognostic (1.67e-1)" "unprognostic (6.09e-4)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" 0.0 0.3 2.5 0.9 8.6 0.0 2.6 0.7 3.7 2.2 1.9 22.4 27.3 0.7 1.3 1.6 1.3 5.5 0.0 2.4 4.6 0.2 0.1 0.1 0.0 2.0 2.1 0.3 3.3 0.0 1.8 0.0 1.3 0.4 37.4 0.8 4.5 0.1 0.0 0.8 33.7 0.8 1.3 0.0 5.0 0.4 6.9 1.0 1.2 0.3 2.0 1.3 2.3 0.7 0.0 0.9 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 23.5 0.0 0.2 0.2 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 6.3 0.2 0.6 0.0 2.7 0.1 27.1 1.7 4.6 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.7 0.2 1.0 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 8.6 0.7 3.7 2.4 4.6 2.0 2.1 1.3 1.3 6.9 0.7 0.1 0.0 0.0 6.5 0.3 0.0 0.5 0.1 0.0 7.4 8.0 8.1 2.2 10.0 5.3 5.5 0.0 0.0 0.2 196.4 0.0 7.5 0.4 0.2 5.9 0.4 28.9 0.0 3.6 4.7 0.0 0.2 13.3 0.2 4.5 0.8 0.0 0.0 0.0 0.0 4.8 47.4 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 1.4 0.0 11.1 1.0 9.2 72.5 0.0 0.0 0.6 94.1 0.1 1.5 0.2 0.0 0.1 0.4 0.1 1.7 0.5 0.0 0.0 0.5 0.0 57.7 9.7 B3GNT4 "B3GN-T4, beta3Gn-T4" ENSG00000176383 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4" Q9C0J1 12 122203681-122208952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;skin 1: 3.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 3.3;Excitatory neurons: 3.2;Proximal tubular cells: 9.7;Spermatogonia: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 5.1;hTCEpi: 4.0;T-47d: 4.2;U-266/84: 3.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055261 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoli "HPA055261: AB_2682765" "unprognostic (1.67e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.60e-2)" "unprognostic (1.32e-3)" "unprognostic (1.98e-1)" "unprognostic (3.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.82e-2)" "unprognostic (3.69e-1)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.24e-1)" "unprognostic (2.79e-1)" "unprognostic (8.97e-2)" "unprognostic (9.47e-2)" 0.2 0.7 2.3 0.1 2.6 1.5 0.2 4.9 3.1 0.3 0.0 0.3 0.2 0.1 0.0 1.3 0.6 0.2 0.1 3.8 0.5 2.7 0.4 0.3 0.1 0.0 0.0 0.2 0.3 0.3 1.4 0.1 0.0 0.4 0.0 0.5 0.5 0.0 0.2 3.1 0.3 0.0 0.0 0.5 0.3 1.6 0.9 0.0 0.4 0.0 0.1 0.1 0.5 1.2 3.4 0.6 0.2 1.4 0.1 0.1 0.6 0.1 0.0 0.2 0.3 2.2 0.3 0.3 0.5 0.0 0.2 1.3 1.7 1.2 0.1 5.1 1.9 0.1 1.3 0.2 0.4 0.5 0.7 0.3 4.0 0.1 0.2 0.5 0.0 1.3 1.0 0.4 0.0 3.2 0.0 0.5 0.4 0.1 1.4 0.2 0.4 0.7 0.5 0.4 0.8 1.1 0.9 0.7 0.4 0.5 4.2 0.1 0.1 0.3 1.7 0.4 0.2 0.4 3.6 0.8 0.3 0.5 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.3 2.6 4.9 3.1 3.8 0.5 0.0 0.0 0.0 0.0 0.9 1.2 0.4 0.0 1.8 0.7 0.3 1.3 0.7 3.3 0.6 0.2 0.7 0.8 0.5 0.0 1.1 0.0 0.0 0.5 0.5 0.6 1.9 1.0 0.4 0.6 0.3 0.3 0.0 0.0 3.2 0.2 1.1 0.3 0.0 0.8 0.0 0.1 0.4 0.0 0.2 0.0 1.4 0.0 2.0 0.6 0.6 0.1 0.3 0.3 0.0 1.9 0.0 0.2 0.0 0.5 0.6 0.4 1.3 0.0 0.4 0.3 0.1 9.7 1.1 0.2 0.0 0.5 0.2 0.8 2.9 0.8 1.4 0.5 0.4 0.1 0.3 0.4 B3GNT7 beta3GnT7 ENSG00000156966 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" Q8NFL0 2 231395710-231401164 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 272.8;Intestinal goblet cells: 145.2;Paneth cells: 126.4;Undifferentiated cells: 354.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 32.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 19.5;HEL: 15.6;THP-1: 14.0;WM-115: 23.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA013881, HPA035625, HPA035626" Enhanced Approved "Golgi apparatus,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 3600000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Mitotic spindle, Cytosol" "HPA013881: , HPA035625: AB_10601118, HPA035626: AB_2674707" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-3)" "unprognostic (1.46e-2)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "unprognostic (1.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.18e-2)" "unprognostic (5.82e-2)" "unprognostic (2.17e-2)" "unprognostic (7.77e-2)" "unprognostic (4.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.18e-1)" "prognostic favorable (6.00e-4)" "unprognostic (3.57e-1)" 3.1 12.9 5.9 2.8 5.1 14.2 3.8 4.0 5.8 2.5 4.6 56.2 25.2 1.9 6.8 2.9 4.6 14.0 4.7 5.6 6.5 2.2 1.2 15.3 1.6 6.0 7.0 16.7 25.4 14.3 8.8 5.4 5.3 3.2 71.2 2.1 7.5 4.4 0.4 5.0 28.4 2.3 4.3 5.1 35.6 1.3 7.3 2.4 8.4 0.3 1.5 3.7 0.6 5.4 0.7 2.8 0.3 0.6 0.1 0.2 1.0 0.2 1.1 0.1 0.1 1.4 19.5 2.2 5.8 0.3 0.2 5.1 0.2 0.0 0.1 0.3 0.5 15.6 0.5 0.9 0.1 0.1 0.8 0.1 1.4 0.2 0.3 1.1 0.2 0.4 0.5 0.4 0.1 0.9 0.2 0.7 6.3 7.7 3.3 0.3 0.1 0.4 0.6 1.7 0.5 0.8 0.3 1.7 0.7 6.9 0.6 14.0 0.2 0.4 0.4 0.2 0.2 2.3 0.9 0.7 0.3 0.2 23.7 0.7 0.1 0.7 2.9 0.5 0.5 9.9 0.1 0.4 6.5 7.0 0.1 0.7 0.2 32.1 0.6 3.1 0.2 1.0 5.9 5.1 4.0 5.8 5.6 6.5 6.0 7.0 5.3 4.3 7.3 5.4 0.9 41.7 30.2 0.3 8.7 2.3 1.7 8.7 0.0 0.4 5.2 2.5 1.1 95.8 29.7 1.8 2.1 0.6 61.7 272.8 0.0 16.1 0.4 13.3 2.2 4.7 103.0 0.4 0.5 84.3 64.9 2.3 51.5 18.5 9.5 17.3 3.3 0.2 11.2 0.0 0.4 145.2 18.3 10.1 38.6 1.2 1.5 9.7 3.6 0.0 2.9 0.5 10.3 55.3 0.2 69.8 126.4 8.2 5.5 11.6 93.2 0.4 82.2 1.8 0.0 0.5 2.3 0.9 1.4 0.0 2.7 2.1 10.0 0.4 354.6 16.2 B4GALNT2 "Cad, GALGT2, Sda" ENSG00000167080 "Beta-1,4-N-acetyl-galactosaminyltransferase 2" Q8NHY0 17 49132460-49176840 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.5;Distal enterocytes: 3.9;Glandular and luminal cells: 5.2;Intestinal goblet cells: 11.5;Ionocytes: 4.1;Proximal enterocytes: 14.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 6.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015721 Approved NA NA "Cluster 9: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA015721: AB_1845245" "unprognostic (4.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.26e-3)" "unprognostic (2.03e-4)" "unprognostic (1.72e-2)" "unprognostic (2.62e-2)" "unprognostic (3.67e-2)" "unprognostic (7.67e-2)" "unprognostic (4.06e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.29e-5)" "unprognostic (3.53e-1)" "unprognostic (1.31e-1)" "unprognostic (7.81e-3)" "unprognostic (2.15e-1)" 1.2 1.3 1.4 7.8 1.0 4.7 0.7 6.6 2.1 0.2 2.3 33.5 2.1 1.1 0.6 0.7 0.4 2.2 1.0 1.7 0.8 9.1 0.9 1.4 2.2 0.7 0.4 1.0 1.7 0.1 0.0 0.7 0.5 0.7 14.2 7.5 2.0 0.3 0.8 2.8 8.4 2.7 0.0 2.2 5.9 1.5 1.1 0.2 5.9 0.1 0.8 0.6 0.0 1.5 0.9 1.7 1.7 3.0 0.1 0.0 0.9 1.3 1.0 0.0 0.1 4.0 1.4 2.1 2.1 0.0 0.6 0.9 0.7 0.1 0.2 1.8 1.8 2.2 5.1 2.1 0.0 1.1 3.5 0.2 1.4 0.3 0.2 0.7 0.0 1.6 1.3 3.3 0.0 1.1 1.4 1.5 2.1 0.3 0.8 2.5 0.7 0.6 5.4 1.4 1.4 1.5 0.6 0.7 0.6 1.7 1.8 1.4 0.6 2.2 1.3 1.3 0.7 2.6 0.9 2.3 0.7 1.4 0.9 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 1.4 1.0 6.6 2.1 1.7 0.8 0.7 0.4 0.5 0.0 1.1 1.5 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.3 0.5 0.0 0.9 5.5 0.0 0.0 0.0 3.9 1.9 0.6 0.7 0.6 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.5 4.1 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 14.8 0.1 0.8 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.1 B4GALT4 beta4Gal-T4 ENSG00000121578 "Beta-1,4-galactosyltransferase 4" O60513 3 119211732-119240946 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 76.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 123.6;Urothelial cells: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ: 125.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046819, HPA063546" Approved Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA046819: AB_2679824, HPA063546: AB_2685036" "unprognostic (4.07e-2)" "unprognostic (1.78e-2)" "unprognostic (3.27e-2)" "unprognostic (1.14e-3)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (6.30e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-1)" "unprognostic (6.10e-3)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" 12.4 9.1 6.8 10.7 8.4 20.1 11.1 6.5 8.1 16.4 8.7 30.6 28.6 14.8 76.0 17.7 21.8 33.2 12.9 7.0 6.9 24.1 16.6 9.9 9.9 6.9 6.7 18.4 19.5 15.1 18.2 25.7 6.9 13.7 35.2 9.9 12.2 14.7 6.3 14.1 32.5 13.6 7.0 9.4 29.3 8.3 7.5 7.4 16.4 6.5 11.5 37.6 10.5 7.2 60.1 100.3 12.8 9.8 36.0 31.1 65.3 125.8 54.4 54.4 56.2 65.4 18.3 11.8 23.9 61.3 32.2 78.6 20.7 15.0 59.9 23.5 6.8 15.1 20.3 31.7 25.3 8.9 15.7 21.2 21.4 23.0 19.3 21.6 5.8 8.0 11.2 11.7 25.5 18.4 5.3 10.7 17.6 34.0 27.2 4.9 11.8 4.7 31.2 60.3 10.9 24.0 29.4 14.6 27.9 28.2 30.2 5.7 4.9 27.3 24.0 15.2 13.5 27.2 21.5 16.1 23.5 10.1 23.5 20.1 4.1 8.3 13.3 5.2 7.3 4.2 7.3 7.9 5.5 3.2 13.6 7.1 2.5 14.8 5.0 3.4 2.7 5.7 6.8 8.4 6.5 8.1 7.0 6.9 6.9 6.7 6.9 7.0 7.5 7.2 8.5 0.0 9.4 7.2 17.1 10.7 22.2 48.9 12.0 10.8 14.9 12.4 9.2 61.5 69.1 7.3 4.2 36.2 46.0 43.2 1.9 30.7 2.1 40.1 16.9 8.4 13.8 7.8 11.9 33.2 123.6 24.0 36.2 74.5 13.3 35.0 3.9 10.8 14.4 18.5 11.1 78.7 16.2 9.8 14.8 2.4 14.9 14.9 14.2 6.5 10.9 22.2 39.1 10.6 10.2 40.5 50.2 28.2 27.4 30.7 59.3 22.6 52.6 10.2 19.7 13.9 16.9 1.7 8.4 14.0 10.5 52.3 23.1 20.0 23.6 171.6 BACH1 "BACH-1, BTBD24" ENSG00000156273 "BTB domain and CNC homolog 1" O14867 21 29194071-29630751 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.4" "Cell type enhanced" "Detected in all" "Early spermatids: 164.4;Late spermatids: 422.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 150.2" "Group enriched" "Detected in all" 4 "granulocytes: 150.2;monocytes: 51.1" "Cell line enhanced" "Detected in all" "Karpas-707: 129.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034949 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA034949: AB_2674376" "unprognostic (1.57e-1)" "unprognostic (8.08e-3)" "unprognostic (2.64e-1)" "unprognostic (2.33e-2)" "unprognostic (6.00e-2)" "unprognostic (2.99e-1)" "unprognostic (9.84e-3)" "unprognostic (1.20e-3)" "unprognostic (5.76e-2)" "unprognostic (5.79e-3)" "prognostic unfavorable (3.11e-5)" "unprognostic (5.63e-2)" "prognostic unfavorable (7.14e-4)" "unprognostic (2.59e-1)" "unprognostic (1.60e-1)" "unprognostic (4.19e-2)" "unprognostic (8.70e-2)" 15.8 12.1 12.3 27.8 13.3 89.4 13.3 27.6 16.0 18.1 9.9 13.4 17.4 19.8 9.7 23.0 9.1 26.1 13.2 10.5 19.5 16.0 30.5 21.4 16.9 23.0 28.4 11.6 17.2 8.3 3.3 50.6 31.0 13.3 13.2 12.0 17.4 8.6 26.3 23.3 17.4 15.9 14.2 20.7 13.5 27.3 16.6 14.2 12.6 12.8 14.8 29.8 13.1 12.3 21.5 8.6 26.1 6.8 20.2 57.7 16.3 23.0 55.0 21.8 24.3 18.1 28.9 25.5 18.0 21.1 22.7 11.1 15.7 30.9 38.6 21.3 13.3 78.7 18.9 18.6 26.8 22.8 28.1 30.3 46.4 42.8 63.4 25.7 11.7 13.9 40.6 129.7 30.2 7.6 19.5 13.0 40.3 8.4 8.9 19.8 61.8 33.1 11.5 16.8 10.8 12.2 12.6 23.5 29.0 26.0 17.1 27.1 29.6 21.3 29.4 23.1 11.8 74.9 51.9 26.9 17.3 27.8 64.9 72.4 51.1 38.6 5.0 40.1 4.1 10.3 8.3 4.3 24.9 13.7 11.9 6.0 150.2 7.1 46.0 6.0 14.8 15.3 12.3 13.3 27.6 16.0 10.5 19.5 23.0 28.4 31.0 14.2 16.6 12.3 31.9 28.9 15.3 12.1 90.6 59.0 53.2 17.9 19.4 16.6 18.3 15.1 20.7 15.7 23.1 14.7 18.8 13.7 33.0 30.7 7.9 19.8 164.4 32.2 45.9 26.0 30.9 33.0 5.1 16.6 15.7 31.3 30.5 64.1 48.6 13.6 22.1 20.9 22.0 13.5 36.9 24.7 12.2 57.1 113.8 422.4 13.4 113.8 21.4 68.4 109.1 10.2 24.7 33.7 25.0 28.2 38.2 14.3 87.8 50.7 25.5 12.8 15.7 12.6 32.9 54.7 36.6 31.5 28.4 34.7 58.1 39.7 31.3 17.4 11.7 48.4 BAG1 ENSG00000107262 "BAG cochaperone 1" Q99933 9 33247820-33264720 "Cancer-related genes, Predicted intracellular proteins" Apoptosis Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1043.2;Late spermatids: 2944.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 437.5;NB-4: 417.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002486, HPA018121, HPA073236" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "CAB002486: AB_563422, HPA018121: AB_1845255, HPA073236: " "unprognostic (4.49e-3)" "unprognostic (4.52e-2)" "unprognostic (2.33e-2)" "unprognostic (1.32e-3)" "unprognostic (5.46e-2)" "unprognostic (3.67e-3)" "unprognostic (2.10e-1)" "unprognostic (1.34e-2)" "unprognostic (4.62e-2)" "unprognostic (7.21e-2)" "unprognostic (4.24e-1)" "unprognostic (2.23e-1)" "prognostic favorable (2.22e-16)" "unprognostic (4.45e-2)" "unprognostic (4.03e-1)" "unprognostic (7.64e-3)" "unprognostic (1.07e-2)" 79.7 76.3 96.6 36.3 106.7 85.0 72.3 102.2 112.3 65.0 106.0 122.5 59.3 59.8 53.9 103.2 54.8 39.1 192.9 86.4 102.8 151.6 83.4 82.5 35.5 107.4 105.2 45.6 91.7 139.6 99.3 47.1 98.8 88.0 75.4 82.2 97.4 68.4 297.7 113.8 66.1 42.7 100.2 66.0 102.5 87.9 104.3 45.1 71.6 206.1 55.2 121.5 78.8 101.6 56.0 56.1 46.8 103.3 69.9 40.9 63.6 46.5 64.6 68.4 69.8 39.7 54.1 181.2 33.6 46.6 24.5 69.8 54.8 37.9 45.0 96.5 52.1 90.2 437.5 62.5 58.9 210.1 110.0 41.5 205.6 32.3 76.8 32.2 82.4 48.0 108.7 92.1 57.8 89.7 152.4 417.0 90.8 73.9 81.2 78.7 63.7 119.6 87.1 164.8 149.1 88.5 192.7 176.9 46.0 18.7 80.5 261.8 44.1 30.5 37.8 89.9 78.0 74.9 125.3 100.4 25.5 114.1 17.7 29.1 20.7 57.9 10.0 22.2 9.0 14.7 11.2 11.9 26.1 25.6 15.7 9.1 10.2 15.3 22.3 33.9 15.2 10.2 96.6 106.7 102.2 112.3 86.4 102.8 107.4 105.2 98.8 100.2 104.3 101.6 107.7 89.8 67.5 5.2 69.4 429.9 279.4 193.3 172.4 84.0 134.1 123.6 144.4 127.2 157.0 218.8 58.4 154.7 113.7 211.4 397.2 135.6 1043.2 109.3 72.2 86.6 198.1 259.1 5.9 189.0 59.9 79.4 104.5 193.3 41.9 36.7 66.8 72.8 104.9 38.7 7.1 287.8 170.9 86.4 162.7 2944.9 85.7 93.9 163.7 2.8 81.0 123.9 88.6 4.5 9.7 131.1 259.2 88.8 110.3 505.4 247.9 286.1 71.8 131.3 98.6 98.5 109.9 87.9 64.4 261.1 561.5 245.9 69.6 103.7 222.4 531.4 BAIAP2 "BAP2, IRSp53, WAML" ENSG00000175866 "BAR/IMD domain containing adaptor protein 2" Q9UQB8 17 81035122-81117432 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 185.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 19.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023310, HPA027421" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA023310: AB_1845264, HPA027421: AB_10602392" "unprognostic (2.20e-1)" "unprognostic (1.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "unprognostic (6.97e-3)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (4.23e-2)" "unprognostic (2.94e-1)" "unprognostic (7.04e-2)" "unprognostic (6.77e-2)" "unprognostic (7.15e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (7.58e-6)" 23.9 18.2 129.1 7.4 140.0 2.6 27.1 95.7 176.1 49.9 104.6 44.0 6.7 30.9 46.5 132.9 37.6 29.3 24.2 163.7 103.1 38.0 85.7 49.1 6.9 68.0 81.0 13.7 13.4 19.9 56.3 31.8 68.3 61.3 12.1 16.2 57.5 27.6 13.1 132.4 14.7 19.3 70.5 11.8 62.3 26.3 119.9 11.8 27.1 9.8 25.3 23.3 73.2 121.9 99.9 45.1 28.1 36.6 22.2 29.0 32.8 40.2 26.1 35.7 15.8 60.9 49.1 0.5 28.3 35.8 73.5 93.6 26.1 46.1 13.7 0.4 32.8 20.2 41.3 46.4 20.7 0.0 28.2 12.5 53.0 29.5 15.4 32.7 19.5 1.1 26.4 0.6 20.6 51.2 4.0 22.3 11.8 65.6 38.1 6.0 6.6 81.3 108.5 34.5 36.8 39.9 64.2 91.3 110.1 23.1 80.4 22.6 23.8 81.6 78.4 13.8 43.4 1.4 0.3 1.4 72.0 3.3 18.3 0.0 7.9 0.5 3.2 9.4 1.0 0.1 1.2 1.0 10.3 0.1 1.3 1.8 5.4 1.9 9.2 19.5 0.5 3.2 129.1 140.0 95.7 176.1 163.7 103.1 68.0 81.0 68.3 70.5 119.9 121.9 74.1 76.9 39.0 13.4 6.2 63.7 138.4 42.3 94.4 37.1 49.4 37.1 22.5 25.8 47.2 22.0 79.2 77.1 16.6 18.8 7.9 9.8 10.5 80.8 10.4 35.7 49.3 0.8 65.3 5.1 9.2 28.0 88.2 79.7 13.4 3.1 45.0 78.6 43.2 11.8 13.6 29.1 24.4 18.3 58.2 29.4 6.8 31.2 40.9 13.1 18.6 18.5 0.0 4.5 5.9 14.8 8.0 3.8 3.1 77.0 3.7 25.4 110.8 19.1 0.0 10.4 13.3 7.6 33.0 103.6 75.3 101.0 13.9 8.2 14.7 185.1 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 1.8 0.6 3.0 2.7 4.6 11.4 2.9 2.2 2.7 3.1 0.2 2.9 2.3 3.3 2.6 5.1 1.9 2.0 1.5 2.3 4.1 0.8 1.0 2.5 5.5 3.8 3.2 2.3 1.6 2.3 1.2 2.3 3.9 2.9 3.6 2.0 1.9 3.6 4.2 8.8 2.1 3.9 3.9 2.6 1.9 6.6 4.1 7.0 1.4 2.3 6.6 2.1 3.8 4.2 12.3 8.8 20.2 9.3 2.7 4.0 12.0 17.3 10.6 17.8 21.8 12.0 12.2 12.6 7.6 8.5 9.5 12.7 16.5 10.5 22.7 11.5 6.4 12.5 13.8 8.7 0.9 13.9 12.7 4.7 1.1 15.0 8.1 4.5 6.1 14.7 7.9 36.0 13.7 10.7 27.9 12.5 14.3 7.9 3.7 24.7 19.8 11.2 3.9 14.0 5.8 8.8 15.0 14.7 5.3 10.9 16.3 13.4 4.7 18.0 14.0 11.7 13.6 10.2 12.6 28.0 7.6 11.3 13.4 3.9 2.0 5.8 4.6 4.0 3.2 9.7 5.4 5.5 3.6 8.2 2.4 4.0 0.3 7.3 3.8 6.9 17.1 2.3 3.0 4.6 2.2 2.7 2.3 4.1 3.8 3.2 3.9 3.9 4.1 4.2 12.3 6.4 2.2 14.7 13.0 68.6 62.2 13.0 14.2 3.3 9.9 14.1 17.4 17.2 12.7 9.2 0.0 18.2 11.3 8.2 3.9 8.0 9.2 13.3 11.9 9.6 1.2 34.5 5.5 6.9 16.0 10.0 10.2 18.0 15.2 28.2 10.0 4.2 12.5 1.7 15.4 13.1 8.2 10.1 12.2 5.7 6.2 11.2 3.6 15.9 16.6 4.4 9.2 19.6 31.7 6.5 6.5 10.1 22.0 22.9 3.2 0.7 12.3 6.8 19.7 15.4 16.9 27.6 43.4 28.6 74.4 5.1 13.4 10.5 14.7 67.2 BARX2 ENSG00000043039 "BARX homeobox 2" Q9UMQ3 11 129375848-129452279 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 158.0;salivary gland: 131.4;vagina: 72.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 128.5;Breast glandular cells: 50.4;Squamous epithelial cells: 136.4;Suprabasal keratinocytes: 82.5;Urothelial cells: 84.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HDLM-2: 163.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.8;hippocampal formation: 1.7" "CAB033311, HPA064966, HPA068414" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Golgi apparatus, Cytosol" "CAB033311: AB_781574, HPA064966: , HPA068414: AB_2685984" "unprognostic (4.25e-2)" "unprognostic (2.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.22e-5)" "unprognostic (3.85e-2)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (1.43e-3)" "unprognostic (4.80e-1)" "unprognostic (1.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.15e-1)" "unprognostic (8.39e-2)" "unprognostic (3.48e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.06e-4)" 0.3 0.0 0.1 1.3 0.3 0.0 14.9 1.1 0.3 24.2 5.5 7.0 17.9 0.1 0.2 158.0 16.7 4.7 0.2 0.3 0.4 5.4 0.0 0.3 0.7 3.0 1.6 0.0 10.3 0.3 1.7 3.6 3.2 4.8 4.9 0.2 131.4 0.6 2.2 34.8 13.0 0.2 1.8 0.0 6.4 2.4 0.4 0.4 0.3 39.3 8.8 0.4 72.2 2.9 23.7 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.3 0.0 1.0 20.9 0.0 5.1 0.0 163.7 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 7.1 0.0 3.9 0.0 6.2 0.0 0.0 0.0 20.6 0.9 0.0 0.0 39.8 0.0 0.3 0.2 0.0 0.0 19.4 0.1 0.4 3.8 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.1 0.3 0.3 0.4 3.0 1.6 3.2 1.8 0.4 2.9 0.2 0.0 1.1 0.3 0.5 43.1 128.5 8.7 3.4 0.6 50.4 16.9 0.5 4.3 8.0 0.0 0.0 13.4 0.8 29.4 7.9 23.7 7.2 11.3 0.6 1.2 1.8 0.0 1.8 0.7 5.8 2.7 6.6 4.6 0.0 0.0 0.0 0.2 1.9 0.0 0.3 13.4 0.0 0.3 2.2 1.6 0.0 0.7 10.6 0.0 0.1 0.7 0.0 0.0 0.3 6.2 29.8 0.4 0.9 25.6 34.0 3.4 11.8 0.3 0.0 0.6 1.7 0.1 5.3 136.4 82.5 4.2 1.7 0.0 19.4 84.8 BBOX1 "BBH, BBOX, G-BBH, gamma-BBH" ENSG00000129151 "Gamma-butyrobetaine hydroxylase 1" O75936 11 27040725-27127809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 467.9;liver: 131.9" "Cell type enriched" "Detected in many" 7 "Proximal tubular cells: 1623.0" "Group enriched" "Detected in many" 6 "glioma: 23.7;renal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTCEpi: 13.7;RPTEC TERT1: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007600, HPA027823" Enhanced Approved Uncertain "Vesicles,Actin filaments" NA NA 35000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Actin filaments" "HPA007600: AB_1845284, HPA027823: AB_10602394" "unprognostic (9.96e-3)" "unprognostic (1.80e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (7.03e-2)" "unprognostic (6.66e-2)" "unprognostic (7.05e-3)" "unprognostic (1.13e-2)" "unprognostic (3.03e-1)" "unprognostic (6.89e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.71e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-1)" "unprognostic (1.73e-3)" 1.4 0.0 24.3 0.0 23.4 0.0 25.1 28.8 34.0 5.1 17.3 0.2 0.0 0.1 8.1 17.5 9.0 9.6 0.0 22.8 25.6 467.9 131.9 0.3 0.1 27.2 33.1 0.0 0.8 0.0 6.9 0.3 35.0 0.5 0.0 0.4 6.1 4.1 0.9 51.8 0.0 0.0 28.8 0.0 0.2 0.1 25.2 1.1 9.6 0.0 0.6 0.1 11.3 27.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.9 13.7 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.2 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 23.4 28.8 34.0 22.8 25.6 27.2 33.1 35.0 28.8 25.2 27.0 0.1 0.0 0.6 66.3 5.3 8.2 9.0 80.9 0.6 0.0 16.3 11.0 0.0 15.7 18.1 46.0 0.0 0.3 0.2 0.0 223.0 0.7 1.1 10.3 0.1 0.3 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.9 0.0 0.1 0.4 27.9 0.0 0.0 0.8 0.0 12.2 0.6 1.1 1.1 0.0 7.1 1.8 4.7 0.0 13.8 0.0 2.0 0.3 0.1 0.0 0.4 0.0 0.2 0.0 1623.0 9.4 0.4 0.0 0.0 1.4 0.0 0.6 16.9 35.8 0.3 5.0 0.0 0.0 2.6 BCAN "BEHAB, CSPG7, MGC13038" ENSG00000132692 Brevican Q96GW7 1 156641390-156659532 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 164.7" "Group enriched" "Detected in some" 8 "Astrocytes: 136.1;Horizontal cells: 109.4;Melanocytes: 186.7;Oligodendrocyte precursor cells: 288.0" "Cancer enriched" "Detected in many" 5 "glioma: 348.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "basophil: 7.8" "Lineage enriched" "Detected in single" 24 "granulocytes: 7.8" "Cell line enhanced" "Detected in many" "HDLM-2: 76.7;K-562: 108.3;U-266/70: 63.3;U-266/84: 133.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007865, CAB025862" Enhanced Supported "Secreted in brain" NA NA 120000 "Cluster 34: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 16: U-266 - Nucleosome" "Cluster 68: Oligodendrocytes - Mixed function" "CAB025862: , HPA007865: AB_1078299" "unprognostic (7.14e-2)" "unprognostic (3.14e-1)" "unprognostic (1.95e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (9.03e-2)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (4.80e-2)" "unprognostic (6.87e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-2)" "unprognostic (9.47e-3)" "unprognostic (2.76e-2)" "unprognostic (8.54e-2)" "unprognostic (5.40e-1)" "unprognostic (1.90e-1)" 0.2 8.4 155.0 0.6 119.5 0.0 0.2 108.3 164.7 2.7 38.3 2.2 7.0 5.9 15.4 0.6 4.0 3.4 0.5 133.1 104.8 0.2 0.1 0.4 0.3 107.5 100.0 0.2 0.1 1.7 2.8 0.7 103.4 0.2 0.0 4.1 1.6 1.8 0.6 15.6 7.8 2.0 94.3 0.5 2.2 1.2 113.7 0.1 0.2 0.0 0.0 0.9 0.9 116.3 44.2 28.4 0.2 8.1 0.0 0.0 11.9 0.4 0.0 0.0 0.0 1.1 21.0 0.1 45.8 0.0 1.0 30.9 0.3 0.0 0.0 76.7 2.9 8.0 20.9 25.6 0.0 3.0 7.3 0.0 0.0 0.0 0.0 1.0 0.0 3.8 108.3 21.0 0.0 12.6 0.1 0.1 2.2 22.2 4.2 0.1 46.7 0.1 0.0 5.4 0.2 0.8 0.1 0.0 43.8 2.2 0.2 2.8 8.8 0.1 24.7 8.7 11.8 63.3 133.2 0.2 8.5 20.4 3.4 7.8 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.0 119.5 108.3 164.7 133.1 104.8 107.5 100.0 103.4 94.3 113.7 116.3 0.2 0.0 0.0 136.1 0.0 6.9 0.0 0.0 0.0 6.0 0.2 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.1 2.9 0.1 1.8 0.7 1.8 0.0 16.8 0.2 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.5 109.4 20.2 0.1 0.0 0.0 1.9 6.9 0.3 0.1 186.7 9.4 0.0 2.1 1.0 288.0 3.5 0.8 0.1 0.0 0.0 0.3 0.1 0.4 0.0 3.2 0.0 0.2 1.7 5.4 6.5 0.0 1.7 0.0 0.2 0.0 0.0 0.0 BCAP29 "BAP29, DKFZp686M2086" ENSG00000075790 "B cell receptor associated protein 29" Q9UHQ4 7 107580246-107629170 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029215, HPA049694" Supported Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA029215: AB_10602331, HPA049694: AB_2680854" "unprognostic (3.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.82e-2)" "unprognostic (1.05e-2)" "unprognostic (5.42e-3)" "unprognostic (4.71e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.43e-2)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (2.31e-2)" "unprognostic (7.36e-2)" "unprognostic (8.34e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-2)" "unprognostic (5.28e-3)" "unprognostic (1.81e-1)" 47.1 25.7 19.4 22.5 23.7 16.7 28.0 18.1 27.0 48.6 12.8 32.6 16.1 42.6 18.6 34.4 21.7 23.0 61.0 24.4 17.9 20.1 33.3 26.0 16.7 17.5 17.6 21.4 18.9 34.5 12.2 26.7 18.0 31.9 31.2 9.6 18.4 25.0 38.7 22.1 18.8 38.2 19.5 18.1 22.4 70.1 19.2 12.8 85.5 31.5 15.7 30.9 32.5 21.1 71.7 22.8 26.4 13.8 65.2 81.6 22.6 80.6 68.2 32.9 39.7 23.2 72.1 13.4 54.5 58.1 75.1 35.8 13.7 38.6 52.5 50.1 17.3 27.1 35.6 26.2 63.3 33.6 41.2 48.9 31.8 46.7 38.0 95.4 116.9 25.3 58.3 33.4 75.4 67.2 23.2 34.3 15.4 29.7 30.0 18.6 34.1 34.6 60.6 49.1 10.2 37.7 68.2 54.9 58.2 39.3 25.6 37.5 113.9 102.5 52.1 94.6 104.7 31.7 67.9 27.5 66.5 30.5 77.2 47.5 10.5 25.5 9.5 13.6 9.3 12.8 7.5 9.5 10.0 8.5 4.3 8.5 3.9 9.9 21.7 10.1 13.6 8.1 19.4 23.7 18.1 27.0 24.4 17.9 17.5 17.6 18.0 19.5 19.2 21.1 169.8 67.3 57.2 35.6 33.9 38.5 80.7 99.0 25.0 35.2 40.4 34.2 117.8 27.1 77.7 23.9 10.4 30.2 31.4 38.1 15.6 46.4 227.1 54.6 93.3 99.0 22.3 73.2 81.1 73.6 50.8 72.9 32.6 102.0 58.3 14.8 73.2 40.7 52.6 8.4 71.3 35.8 69.2 36.6 35.6 95.8 61.2 49.6 37.4 44.0 41.6 28.3 22.6 50.8 49.7 71.2 32.5 89.1 17.7 110.4 15.6 19.5 55.9 26.7 78.9 62.9 91.3 202.2 35.0 46.5 38.8 70.7 33.5 32.0 45.4 83.5 BCAT2 "BCAM, BCT2" ENSG00000105552 "Branched chain amino acid transaminase 2" O15382 19 48795062-48811029 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 254.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054091 Enhanced Approved Nucleoplasm,Mitochondria NA NA 25000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Mitochondria" "HPA054091: AB_2682374" "unprognostic (2.58e-2)" "unprognostic (1.23e-2)" "unprognostic (2.16e-1)" "unprognostic (2.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.97e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (2.98e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.68e-5)" "unprognostic (1.87e-3)" "unprognostic (1.35e-1)" "unprognostic (2.42e-1)" "unprognostic (7.50e-3)" 27.2 85.4 27.5 11.4 27.8 6.1 25.2 34.6 34.5 29.7 72.3 38.8 14.8 27.0 5.3 33.7 30.2 10.7 63.4 29.0 26.5 40.5 22.1 30.4 14.0 28.2 29.7 53.3 76.7 20.1 30.7 12.4 27.8 38.4 17.4 5.6 29.1 17.0 58.7 28.0 23.7 13.5 26.1 19.7 66.4 20.2 30.8 12.0 28.9 29.4 16.5 56.6 29.0 29.2 62.9 73.3 19.3 40.6 78.1 26.3 34.2 27.3 13.8 32.7 31.7 74.5 37.4 73.3 30.2 24.3 10.1 28.8 29.8 47.4 16.5 46.0 76.0 27.0 32.7 5.0 75.3 36.9 24.2 38.5 29.8 24.2 35.0 31.8 45.5 55.3 34.9 43.8 12.2 74.8 50.4 38.9 16.9 98.5 35.7 75.2 33.1 80.8 30.8 254.3 102.6 29.4 41.0 66.7 20.7 13.3 42.3 17.9 25.9 31.5 30.3 37.6 34.3 40.8 58.4 35.8 17.2 56.7 21.0 0.0 14.4 3.0 14.3 16.1 20.1 23.5 17.5 18.8 25.6 20.3 15.7 14.1 0.6 14.8 6.2 28.9 24.9 12.3 27.5 27.8 34.6 34.5 29.0 26.5 28.2 29.7 27.8 26.1 30.8 29.2 13.1 28.9 44.8 59.7 14.1 6.0 28.3 32.3 14.2 10.4 23.5 17.9 25.5 31.5 20.6 12.9 20.9 67.6 11.0 28.8 72.4 38.6 8.0 16.2 22.4 13.5 19.9 6.3 11.2 21.3 25.2 15.3 32.6 23.8 23.5 18.3 12.8 11.2 26.2 1.7 10.6 30.4 38.7 7.9 10.5 10.2 17.4 7.5 24.9 8.4 21.6 7.3 7.2 9.0 11.2 15.8 17.7 30.1 15.1 16.1 13.9 39.4 13.2 13.4 19.7 9.9 17.3 8.0 19.5 32.6 7.1 45.8 9.5 21.9 33.9 47.7 BCL11A "BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, ZNF856" ENSG00000119866 "BAF chromatin remodeling complex subunit BCL11A" Q9H165 2 60450520-60554467 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.8;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "B-cells: 149.0;Basal squamous epithelial cells: 118.4;dendritic cells: 140.3;Excitatory neurons: 180.8;Inhibitory neurons: 153.2;Squamous epithelial cells: 120.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 312.7;naive B-cell: 415.7;plasmacytoid DC: 899.0" "Group enriched" "Detected in all" 15 "B-cells: 415.7;dendritic cells: 899.0" "Cell line enhanced" "Detected in many" "Daudi: 51.1;MOLT-4: 49.0;REH: 48.3;U-698: 106.7;U-937: 34.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 52.5;cerebral cortex: 82.3;hippocampal formation: 69.2;olfactory bulb: 66.7" "CAB014891, HPA029003, HPA075941" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies" "CAB014891: , HPA029003: AB_2672863, HPA075941: " "unprognostic (4.10e-3)" "unprognostic (6.72e-2)" "unprognostic (4.50e-2)" "unprognostic (9.41e-3)" "unprognostic (2.37e-1)" "unprognostic (4.47e-3)" "unprognostic (2.53e-2)" "unprognostic (1.68e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-1)" "unprognostic (4.27e-4)" "unprognostic (1.23e-2)" "unprognostic (2.35e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-1)" "unprognostic (4.40e-2)" "unprognostic (2.99e-2)" 0.7 2.1 31.4 11.3 34.7 25.3 7.1 10.5 47.8 5.2 9.7 18.4 9.7 2.1 1.4 18.4 5.7 2.5 8.0 38.7 15.5 1.0 0.5 2.1 29.2 31.6 15.3 0.6 10.8 1.7 3.0 0.9 31.0 7.8 6.1 1.7 13.8 1.9 1.7 33.2 13.9 3.4 15.9 19.6 4.8 2.0 15.9 33.9 2.3 0.2 40.9 3.3 11.5 38.7 0.6 0.0 4.2 0.1 0.8 0.8 0.3 1.5 0.0 0.1 0.0 0.0 0.2 51.1 0.2 0.2 0.0 10.5 15.4 7.4 0.2 0.9 15.2 0.1 0.6 0.2 0.0 18.7 0.1 1.7 4.1 0.0 2.5 4.0 2.6 17.1 0.8 0.3 0.1 0.1 49.0 19.9 28.6 7.7 0.2 48.3 1.3 19.7 0.0 0.9 20.1 4.8 0.3 0.4 0.3 8.0 0.3 9.1 1.0 0.3 11.6 0.3 0.1 0.8 0.2 106.7 0.1 34.0 1.6 4.5 23.8 5.1 0.5 44.1 1.1 312.7 0.5 0.5 89.9 415.7 1.3 1.1 11.0 8.4 33.7 899.0 1.1 11.4 31.4 34.7 10.5 47.8 38.7 15.5 31.6 15.3 31.0 15.9 15.9 38.7 0.6 0.0 7.4 3.6 149.0 46.3 16.0 34.0 118.4 2.5 31.6 28.6 18.2 4.3 11.7 1.8 0.0 0.6 140.3 7.5 5.9 9.5 12.0 3.9 2.0 1.4 19.8 69.6 180.8 6.4 0.5 3.6 5.1 4.8 10.1 67.4 0.7 0.1 43.2 52.2 153.2 13.6 6.1 7.0 86.1 5.0 0.3 20.5 16.0 11.2 16.0 0.3 0.0 3.5 4.6 4.7 12.5 0.0 6.0 11.7 16.2 0.5 5.5 0.3 0.0 0.2 2.0 2.9 6.9 120.3 69.9 0.8 4.6 1.0 28.9 5.8 BCL11B "CTIP-2, CTIP2, hRIT1-alpha, ZNF856B" ENSG00000127152 "BAF chromatin remodeling complex subunit BCL11B" Q9C0K0 14 99169287-99272197 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 21.2;lymphoid tissue: 36.6;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.8;Basal squamous epithelial cells: 73.4;Excitatory neurons: 57.5;Inhibitory neurons: 105.7;NK-cells: 51.5;Suprabasal keratinocytes: 71.3;T-cells: 133.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 21.2;cerebral cortex: 17.2;hippocampal formation: 18.9" "Group enriched" "Detected in many" 8 "gdT-cell: 2.0;MAIT T-cell: 1.8;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.4;naive CD4 T-cell: 4.6;naive CD8 T-cell: 3.1;T-reg: 2.0" "Lineage enriched" "Detected in single" 14 "T-cells: 4.6" "Group enriched" "Detected in some" 6 "JURKAT: 38.3;MOLT-4: 47.3" "Region enhanced" "Detected in many" "basal ganglia: 64.3" "Region enhanced" "Detected in many" "basal ganglia: 30.0" HPA049117 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nucleoli fibrillar center" "HPA049117: AB_2680639" "unprognostic (1.64e-5)" "unprognostic (4.66e-2)" "unprognostic (2.35e-2)" "unprognostic (1.87e-2)" "unprognostic (9.37e-2)" "unprognostic (5.97e-2)" "unprognostic (4.75e-2)" "unprognostic (6.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.12e-1)" "unprognostic (1.60e-6)" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (3.31e-3)" "prognostic favorable (7.48e-4)" 0.4 0.3 8.0 5.1 21.2 4.9 1.1 0.0 17.2 0.9 0.0 1.2 2.0 0.2 0.5 4.3 0.3 0.9 0.1 18.9 1.1 0.3 0.4 1.1 10.2 0.3 0.8 0.2 0.1 0.0 0.2 0.1 0.0 0.5 1.4 0.0 1.7 0.3 0.2 15.0 3.5 0.2 1.5 4.4 1.9 0.5 2.0 36.6 0.8 0.0 7.5 1.3 2.9 3.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 1.7 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.0 0.2 0.0 0.0 38.3 0.0 4.1 0.0 2.8 47.3 0.8 0.5 3.6 0.0 7.0 0.0 0.0 0.0 2.6 3.7 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 1.7 0.2 0.0 2.6 0.1 0.0 2.0 0.7 0.0 0.0 0.0 0.1 2.0 0.0 1.8 0.0 2.8 2.4 0.0 0.0 4.6 3.1 0.0 0.3 0.0 0.0 2.0 0.8 8.0 21.2 0.0 17.2 18.9 1.1 0.3 0.8 0.0 1.5 2.0 3.9 1.3 3.2 0.0 1.3 6.4 62.8 1.6 6.3 73.4 0.4 4.3 4.4 3.8 4.3 1.3 0.0 0.0 0.1 44.2 3.8 1.9 0.2 0.2 0.2 0.2 1.2 1.2 5.3 57.5 0.5 0.0 3.3 2.0 0.3 5.1 0.2 3.3 0.3 0.3 0.0 105.7 4.9 2.0 1.0 11.4 0.4 0.6 4.0 5.4 1.0 4.9 0.0 51.5 32.2 2.0 1.1 5.4 0.0 24.4 0.6 10.1 0.5 0.3 0.1 0.0 0.5 1.9 1.6 5.8 42.7 71.3 0.0 133.4 0.1 9.7 0.6 BCL2L10 "BCL-B, Boo, Diva" ENSG00000137875 "BCL2 like 10" Q9HD36 15 52109263-52112775 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 9.6;skin 1: 6.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 13.7;Proximal enterocytes: 11.4;Proximal tubular cells: 9.8;Squamous epithelial cells: 7.9;Suprabasal keratinocytes: 8.7" "Cancer enhanced" "Detected in many" "liver cancer: 6.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "NB-4: 34.1" "Not detected" "Not detected" HPA042222 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" "HPA042222: AB_10794271" "unprognostic (5.33e-4)" "unprognostic (1.26e-1)" "unprognostic (1.58e-1)" "unprognostic (3.22e-4)" "unprognostic (1.19e-2)" "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" "unprognostic (4.80e-3)" "unprognostic (8.86e-2)" "unprognostic (3.47e-2)" "unprognostic (9.52e-2)" "unprognostic (3.83e-1)" "unprognostic (2.18e-9)" "unprognostic (9.59e-2)" "unprognostic (1.86e-1)" "unprognostic (1.92e-1)" "unprognostic (3.20e-2)" 0.2 2.6 1.2 0.3 1.6 0.1 1.0 0.8 1.1 2.3 0.5 1.0 1.9 0.8 0.0 3.5 0.6 0.9 0.0 0.9 1.7 3.1 9.6 0.0 0.2 0.6 0.6 0.4 0.6 0.2 1.2 0.0 0.8 0.5 0.8 0.4 0.8 0.1 0.1 6.9 2.1 0.2 0.5 0.6 0.9 0.2 1.8 0.1 0.3 0.0 0.2 1.2 3.6 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.7 0.4 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.1 4.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 1.6 0.8 1.1 0.9 1.7 0.6 0.6 0.8 0.5 1.8 0.7 0.1 0.0 0.0 0.0 0.6 6.1 5.3 2.5 4.6 1.0 1.7 2.5 0.3 4.3 0.7 0.0 0.0 0.1 0.2 2.8 13.7 2.2 0.0 1.4 1.4 0.3 0.0 0.8 0.4 1.5 0.2 0.3 0.0 5.2 0.0 0.1 0.0 4.5 0.1 0.0 0.2 2.1 6.1 0.0 0.7 0.1 0.3 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.7 0.4 1.1 2.0 11.4 9.8 0.4 0.2 0.0 0.2 0.3 0.0 0.1 7.9 8.7 0.1 0.2 0.1 3.1 5.4 BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96256210-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 23.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 40.8;Basal squamous epithelial cells: 41.5;Fibroblasts: 17.0;Squamous epithelial cells: 22.5;Suprabasal keratinocytes: 17.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.0;fHDF/TERT166: 18.8;HHSteC: 29.2;hTEC/SVTERT24-B: 29.2;U-2197: 27.9;U-87 MG: 90.1" "Low region specificity" "Detected in single" HPA002935 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA002935: AB_1078274" "unprognostic (6.15e-2)" "unprognostic (2.78e-2)" "unprognostic (9.40e-2)" "unprognostic (3.06e-3)" "unprognostic (6.76e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-2)" "unprognostic (2.34e-3)" "unprognostic (2.23e-2)" "unprognostic (2.96e-2)" "unprognostic (4.80e-3)" "unprognostic (2.36e-1)" "unprognostic (9.96e-6)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-3)" "unprognostic (4.66e-2)" 10.7 0.2 0.4 5.2 0.7 0.0 1.2 1.3 0.9 6.9 0.3 4.2 1.8 0.9 0.6 13.4 5.1 14.1 1.6 0.5 0.3 8.3 0.2 1.3 0.1 0.5 0.4 0.4 6.5 0.0 0.2 0.7 0.5 1.5 2.7 0.2 1.9 0.2 0.1 3.3 3.6 6.0 0.3 0.1 4.5 2.3 0.4 0.1 1.1 0.5 0.4 23.4 7.4 0.6 0.5 1.4 0.0 1.2 2.9 9.9 0.1 2.3 32.0 3.1 0.5 0.0 0.6 0.0 0.1 18.8 1.4 2.4 0.0 0.4 5.0 0.3 0.1 0.0 2.7 0.0 29.2 0.0 0.1 1.0 2.4 29.2 0.6 0.2 0.0 0.0 0.0 0.1 4.2 0.4 0.0 0.0 0.0 1.7 0.2 0.0 7.2 0.2 0.2 0.1 0.7 0.0 8.2 2.4 0.0 0.3 0.0 0.0 0.0 9.5 0.6 27.9 1.8 4.6 9.3 0.0 90.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 1.3 0.9 0.5 0.3 0.5 0.4 0.5 0.3 0.4 0.6 1.4 0.0 0.5 0.0 0.0 40.8 2.9 9.0 41.5 1.7 0.0 0.3 0.8 0.0 3.2 0.0 0.0 0.3 0.0 5.5 7.9 2.3 1.1 0.9 3.7 5.0 0.0 0.0 0.4 1.2 1.4 17.0 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.1 8.2 0.0 6.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.3 4.9 0.4 0.0 1.6 2.3 0.1 3.3 0.1 0.0 1.6 2.5 0.9 1.3 22.5 17.2 1.5 0.2 0.0 0.4 2.8 BEND6 "bA203B9.1, C6orf65, FLJ30162" ENSG00000151917 "BEN domain containing 6" Q5SZJ8 6 56955107-57027346 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 30.9;retina: 11.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.6;Excitatory neurons: 87.3;Horizontal cells: 42.1;Inhibitory neurons: 118.6;Oligodendrocyte precursor cells: 49.8" "Cancer enriched" "Detected in many" 6 "glioma: 4.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 8.8" "Lineage enriched" "Detected in many" 6 "dendritic cells: 8.8" "Cell line enhanced" "Detected in many" "ASC TERT1: 28.8;fHDF/TERT166: 28.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031605, HPA052973" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA031605: AB_10602395, HPA052973: AB_2682002" "unprognostic (4.27e-1)" "unprognostic (7.05e-2)" "unprognostic (4.42e-2)" "unprognostic (1.18e-6)" "unprognostic (2.44e-1)" "unprognostic (2.10e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (9.41e-3)" "unprognostic (1.57e-1)" "unprognostic (8.82e-2)" "unprognostic (1.94e-2)" "unprognostic (9.84e-6)" "unprognostic (9.27e-3)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.98e-3)" 1.2 2.1 12.1 1.5 14.2 0.7 0.6 30.5 30.9 4.0 2.9 1.4 0.5 2.8 0.7 1.2 1.0 3.8 2.4 12.6 16.0 0.6 0.2 0.6 0.9 19.5 16.0 2.0 0.4 0.7 1.7 2.0 20.4 2.4 1.5 11.8 0.5 2.4 3.9 1.0 0.7 3.6 12.1 0.8 0.8 1.0 15.7 1.1 0.8 0.6 0.8 2.8 1.7 21.7 5.4 2.2 1.3 0.6 17.6 28.8 4.9 16.1 15.6 7.1 8.2 0.2 2.4 0.1 5.2 28.7 9.9 0.7 1.8 0.8 8.7 2.4 1.0 3.6 7.5 0.4 4.7 10.3 0.2 12.7 4.5 9.8 4.3 11.9 4.7 13.3 4.6 9.2 14.3 5.5 6.2 2.5 4.4 0.3 1.3 0.1 0.2 2.6 2.6 5.4 6.1 6.2 10.8 1.3 1.4 6.1 0.3 5.9 6.1 21.5 0.7 14.5 3.6 12.6 15.2 4.3 12.6 6.5 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 8.8 0.0 0.1 12.1 14.2 30.5 30.9 12.6 16.0 19.5 16.0 20.4 12.1 15.7 21.7 0.4 0.0 0.0 16.6 0.3 0.9 0.2 0.2 0.0 82.6 0.2 1.1 3.6 0.0 0.7 0.0 4.2 0.5 10.8 0.0 0.0 0.2 0.6 0.5 11.9 0.2 0.0 0.0 87.3 0.4 1.6 5.6 0.0 0.5 0.0 13.5 1.1 0.0 0.1 42.1 118.6 0.0 0.0 0.0 4.0 0.8 1.8 1.1 3.6 13.1 0.3 4.9 0.0 49.8 22.9 0.6 0.0 3.0 0.0 0.4 0.0 1.0 0.0 4.8 0.0 8.7 2.7 0.7 5.8 0.2 1.0 0.0 0.1 4.4 0.0 0.1 BEST3 "MGC13168, MGC40411, VMD2L3" ENSG00000127325 "Bestrophin 3" Q8N1M1 12 69643360-69699476 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 69.1;tongue: 55.8" "Cell type enhanced" "Detected in some" "Early spermatids: 10.3;Late spermatids: 17.9;Oligodendrocyte precursor cells: 70.4;Skeletal myocytes: 28.1" "Cancer enriched" "Detected in single" 9 "glioma: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "REH: 36.1;RPMI-8226: 38.4;U-698: 63.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA054582 Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" "HPA054582: AB_2682530" "unprognostic (1.53e-1)" "unprognostic (7.00e-2)" "unprognostic (9.83e-2)" "unprognostic (1.67e-2)" "unprognostic (5.15e-3)" "unprognostic (2.26e-3)" "unprognostic (7.30e-7)" "unprognostic (1.81e-1)" "unprognostic (1.74e-2)" "unprognostic (5.36e-2)" "unprognostic (1.19e-1)" "unprognostic (4.08e-2)" "unprognostic (4.82e-2)" "unprognostic (4.47e-2)" "unprognostic (3.03e-1)" 0.0 0.6 3.9 0.1 3.7 2.8 0.6 15.4 5.8 0.1 0.7 0.2 0.2 0.1 0.6 1.9 0.1 0.2 0.4 4.2 1.4 0.4 0.3 0.1 0.2 5.2 3.8 0.2 1.1 0.1 1.1 0.3 5.3 1.9 0.2 2.6 3.1 0.1 69.1 0.9 0.1 0.0 2.7 0.1 0.1 3.1 3.2 1.4 0.1 55.8 0.2 0.0 0.0 7.8 0.2 0.5 1.3 0.1 0.0 0.0 0.3 0.3 0.3 0.7 0.8 0.3 0.4 2.4 0.6 0.0 2.0 0.2 0.0 0.1 0.8 0.5 0.1 1.0 0.8 0.3 0.0 0.3 0.0 0.3 0.0 1.1 0.2 0.1 0.4 0.1 0.5 0.0 1.5 0.2 0.0 0.1 1.4 0.7 0.5 36.1 1.1 38.4 1.8 0.1 0.7 0.0 0.2 0.2 0.0 2.3 0.3 0.0 0.2 0.3 0.9 0.2 1.3 0.2 0.4 63.7 2.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 3.9 3.7 15.4 5.8 4.2 1.4 5.2 3.8 5.3 2.7 3.2 7.8 0.0 0.0 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 1.2 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 10.3 0.1 0.0 0.0 0.0 1.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 17.9 0.0 0.2 1.8 0.0 0.0 7.6 0.0 70.4 0.1 0.8 0.0 0.0 0.0 0.6 0.0 7.0 0.0 0.3 0.0 28.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 BEST4 VMD2L2 ENSG00000142959 "Bestrophin 4" Q8NFU0 1 44783585-44788170 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 16.4;fallopian tube: 8.3;intestine: 27.4" "Cell type enriched" "Detected in some" 25 "Paneth cells: 1290.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;U-698: 1.8" "Low region specificity" "Detected in many" HPA058564 Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA058564: AB_2683759" "unprognostic (5.76e-2)" "unprognostic (1.22e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-2)" "unprognostic (6.51e-3)" "unprognostic (1.09e-1)" "unprognostic (8.39e-2)" "unprognostic (1.45e-3)" "unprognostic (1.04e-1)" "unprognostic (8.97e-2)" "unprognostic (5.72e-2)" "unprognostic (1.29e-1)" "unprognostic (2.69e-5)" "unprognostic (1.43e-1)" "unprognostic (3.72e-1)" "unprognostic (1.28e-1)" "unprognostic (4.13e-3)" 0.2 1.9 1.2 0.7 1.1 0.7 0.5 2.2 1.3 1.6 16.4 27.4 9.1 0.7 3.0 0.2 8.3 0.2 0.3 0.8 1.7 0.5 0.6 1.9 0.6 1.9 3.3 0.5 0.3 0.3 2.7 0.2 1.5 0.4 16.0 1.1 0.3 0.5 0.4 2.2 8.1 0.5 1.3 0.5 0.4 0.7 1.6 0.5 0.6 0.1 0.4 0.3 0.2 1.0 0.0 0.2 0.3 0.4 0.1 0.1 1.1 0.2 0.1 0.1 0.0 0.1 0.5 0.1 0.5 0.1 0.3 0.5 0.1 0.0 0.1 0.3 0.2 0.0 0.8 2.5 0.1 0.0 0.3 0.2 0.3 0.1 0.2 0.6 0.3 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.8 0.3 0.1 0.1 0.1 0.2 0.4 0.0 0.5 0.1 0.1 0.1 0.2 0.4 0.1 1.8 0.4 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.6 0.8 0.6 0.7 0.0 0.5 0.2 0.5 0.1 0.3 0.0 0.3 0.6 0.1 1.2 1.1 2.2 1.3 0.8 1.7 1.9 3.3 1.5 1.3 1.6 1.0 0.2 0.0 0.0 0.0 0.8 0.3 0.8 3.4 0.0 0.8 0.4 1.0 0.5 0.0 4.2 5.5 0.0 0.3 0.4 31.2 1.9 0.7 0.0 26.7 0.5 0.2 2.4 0.0 1.9 0.8 0.2 0.6 0.5 1.2 0.0 0.3 0.4 0.0 0.3 0.0 4.3 3.2 0.0 0.0 0.9 0.2 0.9 0.2 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.6 1290.4 0.4 0.4 0.7 6.1 1.0 50.1 0.2 0.0 1.2 0.8 0.7 1.6 0.0 0.6 0.3 1.4 0.4 9.1 0.5 BFSP1 "CP115, CP94, filensin, LIFL-H" ENSG00000125864 "Beaded filament structural protein 1" Q12934 20 17493905-17569220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 5.7;NK-cells: 17.5;Spermatogonia: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.5" "Lineage enhanced" "Detected in single" "T-cells: 2.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 10.8;RPTEC TERT1: 19.5;SK-BR-3: 10.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "amygdala: 2.5;cerebral cortex: 3.2;hippocampal formation: 3.6" "HPA040748, HPA042038" Enhanced Supported "Plasma membrane,Cytosol" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA040748: AB_10963786, HPA042038: AB_10964054" "unprognostic (2.24e-3)" "unprognostic (1.99e-1)" "unprognostic (1.63e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.07e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-6)" "unprognostic (5.11e-2)" "unprognostic (5.53e-1)" "unprognostic (2.10e-4)" "unprognostic (1.75e-1)" "unprognostic (8.81e-2)" "unprognostic (3.35e-4)" "unprognostic (4.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.78e-2)" "unprognostic (7.50e-2)" 1.1 1.3 2.0 0.5 2.2 0.4 1.1 1.6 2.1 1.3 2.0 1.3 0.3 1.8 1.4 1.1 1.3 1.3 0.7 2.2 2.1 3.7 0.3 1.7 0.3 1.7 1.8 1.5 1.9 1.0 0.9 1.9 1.8 1.2 0.5 0.4 1.5 1.1 0.3 1.0 0.7 1.1 1.5 0.4 0.9 3.8 2.1 0.2 2.5 0.4 0.3 1.3 0.9 2.4 0.8 8.1 2.6 0.3 0.7 2.6 0.4 2.0 9.5 1.3 1.2 3.7 7.0 0.0 1.6 1.2 5.1 1.2 2.8 1.6 1.0 1.8 2.1 0.6 1.2 1.1 1.5 0.5 0.9 3.1 4.9 0.7 2.3 10.8 5.7 0.5 0.3 0.4 4.2 1.6 0.0 1.2 6.1 5.2 2.2 0.0 1.8 0.4 19.5 1.5 2.7 0.3 2.4 10.6 4.3 1.2 5.2 1.8 6.5 0.3 0.6 0.7 2.0 0.0 0.1 0.0 1.4 0.0 1.6 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.0 0.2 2.0 2.2 1.6 2.1 2.2 2.1 1.7 1.8 1.8 1.5 2.1 2.4 3.8 3.2 1.7 0.7 0.0 0.9 0.5 0.7 0.0 0.2 1.9 1.5 1.2 1.5 0.4 0.0 0.0 1.2 2.6 0.1 1.9 0.8 1.3 1.1 0.4 3.1 0.0 0.8 2.1 0.9 1.7 1.2 1.5 0.6 0.0 0.2 3.9 0.2 0.5 0.0 1.2 0.2 0.0 0.0 0.8 5.7 1.8 0.2 1.8 2.8 0.0 1.0 17.5 0.5 1.1 0.8 0.0 0.0 0.4 0.4 0.0 0.3 1.8 0.1 0.0 0.5 1.0 1.1 11.9 1.1 0.9 0.4 1.0 0.4 0.3 0.5 BGN "DSPG1, SLRR1A" ENSG00000182492 Biglycan P21810 X 153494980-153509546 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 795.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 223.5;Peritubular cells: 782.7;Sertoli cells: 1485.7;Smooth muscle cells: 401.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 312.6;BJ hTERT+: 400.8;fHDF/TERT166: 568.9;HSkMC: 283.9;hTEC/SVTERT24-B: 235.2;HUVEC TERT2: 561.2;U-138 MG: 249.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003157, CAB003678" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 3300000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Endoplasmic reticulum" "CAB003678: AB_425325, HPA003157: AB_1078282" "unprognostic (1.74e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-3)" "unprognostic (3.60e-1)" "unprognostic (5.42e-2)" "unprognostic (3.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.22e-2)" "unprognostic (1.76e-3)" "unprognostic (1.30e-2)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (6.00e-8)" "unprognostic (7.05e-3)" "unprognostic (2.40e-2)" "unprognostic (5.66e-2)" "unprognostic (2.57e-3)" 165.8 213.0 54.1 93.1 57.6 0.3 118.0 51.2 91.5 371.0 69.5 69.3 22.0 234.4 83.7 45.8 143.7 326.1 795.8 56.1 48.7 396.5 347.9 477.3 42.4 50.6 50.8 94.9 67.9 26.6 144.1 199.1 53.2 184.2 24.8 1.1 107.7 135.5 32.4 118.9 48.8 213.2 45.5 352.1 51.6 69.9 64.6 15.9 250.0 46.7 35.9 126.8 180.0 65.4 0.0 0.0 29.7 0.1 31.5 70.5 1.1 312.6 400.8 56.7 18.6 39.5 0.0 0.0 56.9 568.9 2.0 0.1 0.0 0.0 10.2 0.0 0.0 0.0 0.6 3.9 27.0 0.0 0.2 283.9 2.2 235.2 10.7 29.0 561.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 1.5 0.3 0.2 0.0 0.1 0.0 0.6 0.4 0.0 0.0 1.1 11.8 1.3 0.0 120.0 249.5 2.3 1.0 1.5 0.9 0.1 0.0 0.1 0.3 114.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 57.6 51.2 91.5 56.1 48.7 50.6 50.8 53.2 45.5 64.6 65.4 30.5 3.2 5.6 5.9 0.6 104.1 1.3 7.3 5.7 0.2 1.2 5.6 16.1 4.3 2.5 9.2 0.0 15.5 0.7 0.0 1.9 2.7 1.8 1.4 28.3 45.2 0.0 5.3 0.1 0.2 50.0 180.0 7.7 1.1 3.8 8.4 223.5 1.6 4.4 3.3 0.1 0.0 0.0 4.0 43.6 13.5 147.9 3.0 35.6 25.3 2.0 0.1 0.0 20.6 0.0 1.2 0.0 782.7 0.0 3.0 0.0 0.8 1.6 0.2 1485.7 3.1 401.3 0.8 1.2 1.8 54.1 56.9 3.0 7.7 0.0 1.6 BHLHA15 "BHLHB8, MIST1" ENSG00000180535 "Basic helix-loop-helix family member a15" Q7RTS1 7 98211439-98215457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "pancreas: 502.8;salivary gland: 145.9" "Cell type enriched" "Detected in single" 25 "Plasma cells: 12.6" "Cancer enriched" "Detected in many" 4 "prostate cancer: 16.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Karpas-707: 53.5;RPMI-8226: 72.0;U-266/70: 67.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034083, HPA047834" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Golgi apparatus" "CAB034083: AB_2065216, HPA047834: AB_2680172" "unprognostic (2.80e-2)" "unprognostic (9.45e-3)" "unprognostic (8.10e-2)" "unprognostic (6.66e-2)" "unprognostic (4.33e-3)" "unprognostic (1.10e-2)" "unprognostic (4.05e-2)" "unprognostic (1.37e-1)" "unprognostic (3.60e-1)" "unprognostic (4.28e-2)" "unprognostic (1.46e-1)" "unprognostic (1.88e-1)" "unprognostic (3.70e-4)" "unprognostic (3.36e-1)" "unprognostic (1.94e-1)" "unprognostic (2.95e-1)" "unprognostic (8.25e-3)" 0.1 0.1 0.8 3.6 0.6 0.3 1.5 0.1 2.0 1.9 0.1 4.0 4.0 0.1 0.8 0.9 0.1 0.7 0.2 1.3 0.9 0.6 5.2 0.9 3.8 0.6 0.5 0.4 502.8 0.1 1.5 0.1 0.6 8.5 1.5 0.0 145.9 3.9 0.2 0.6 3.4 0.0 1.0 5.0 31.3 0.2 1.5 0.7 1.9 0.0 4.7 2.5 0.2 0.4 0.3 0.1 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.1 0.8 0.9 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.6 6.7 5.9 0.0 0.1 0.0 0.4 0.4 0.2 0.0 0.2 0.0 0.0 53.5 0.0 0.9 0.0 0.0 0.8 6.2 0.8 0.4 0.0 72.0 0.3 0.0 4.3 1.2 0.0 11.2 0.0 0.0 0.7 0.1 0.0 0.0 0.7 0.1 0.1 67.6 5.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.6 0.1 2.0 1.3 0.9 0.6 0.5 0.6 1.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 BICD2 KIAA0699 ENSG00000185963 "BICD cargo adaptor 2" Q8TD16 9 92711363-92764833 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Squamous epithelial cells: 103.2;Suprabasal keratinocytes: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023013, HPA024452" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane, Cytosol" "HPA023013: AB_1845352, HPA024452: AB_1845353" "unprognostic (9.99e-3)" "unprognostic (1.98e-1)" "unprognostic (7.84e-3)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "unprognostic (2.86e-1)" "unprognostic (2.37e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (6.54e-3)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (3.95e-1)" "unprognostic (1.39e-2)" 15.4 10.6 11.4 13.5 10.0 12.0 10.9 10.9 10.5 20.8 7.8 18.5 4.6 15.5 6.0 47.0 12.8 9.4 19.8 11.1 8.6 9.1 8.5 16.0 14.7 11.0 9.8 12.5 8.9 17.7 6.0 10.4 10.3 11.3 5.0 6.5 14.6 13.1 22.3 63.4 10.4 13.7 10.5 17.3 9.5 9.4 10.0 13.8 10.0 15.3 16.8 15.2 30.9 12.3 32.6 26.5 19.2 19.8 36.6 25.1 27.1 30.8 22.2 17.2 13.6 15.6 14.4 36.3 19.5 34.4 22.0 99.4 21.8 49.1 19.4 17.4 23.5 19.2 25.6 21.7 21.8 26.9 30.0 25.8 67.1 28.8 22.0 20.4 26.0 15.4 19.3 27.5 38.1 21.4 25.6 16.7 13.3 23.8 32.0 27.8 41.8 19.3 27.8 27.0 13.4 20.7 21.7 19.9 14.3 19.2 8.2 12.3 34.9 31.8 21.1 53.9 33.9 22.5 17.5 31.9 26.9 16.3 28.4 1.6 3.4 4.4 1.2 3.6 1.2 1.8 1.4 1.6 3.8 2.0 1.3 1.2 7.5 1.1 5.9 3.2 0.9 1.7 11.4 10.0 10.9 10.5 11.1 8.6 11.0 9.8 10.3 10.5 10.0 12.3 21.7 28.9 12.7 14.7 27.6 73.7 17.1 19.2 83.6 12.8 11.4 10.2 54.5 8.6 16.2 7.3 6.2 8.5 26.1 3.4 3.9 10.1 6.5 21.3 26.7 26.4 10.8 16.0 16.2 5.1 6.5 26.0 5.6 21.1 24.1 13.0 19.2 7.5 14.2 15.2 14.0 1.9 12.2 32.4 30.2 7.6 21.1 40.7 16.0 19.7 38.9 22.0 7.2 9.5 18.5 8.5 3.6 33.4 22.1 18.7 0.8 6.7 14.0 6.4 19.7 23.0 33.1 9.7 8.4 103.2 130.8 7.3 17.2 13.8 3.6 20.3 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;lymphoid tissue: 41.0;testis: 19.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.7;Early spermatids: 94.1;Erythroid cells: 166.7;Extravillous trophoblasts: 162.0;Spermatocytes: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 0.9 1.1 0.3 8.5 0.5 37.9 5.1 0.6 0.6 1.9 0.4 6.7 7.9 1.6 0.0 12.8 0.6 1.1 0.5 0.4 0.4 0.7 2.1 1.9 16.2 0.6 0.6 0.4 0.6 0.2 0.2 6.1 0.5 0.6 8.0 0.1 1.8 0.2 1.1 5.8 7.6 4.3 0.4 5.8 3.7 19.6 1.0 41.0 0.4 0.1 16.3 2.6 3.2 0.8 139.1 126.2 111.3 121.5 6.7 11.3 41.0 103.6 57.5 144.0 94.2 104.0 52.9 140.7 41.5 60.5 108.7 71.9 113.6 66.6 125.2 48.2 157.5 93.2 71.4 123.1 0.8 90.8 67.0 3.9 4.5 79.8 59.2 21.0 103.5 104.3 118.8 116.0 112.6 79.7 195.5 86.2 83.4 96.3 218.0 100.5 180.2 108.4 34.5 50.2 136.8 94.8 80.3 88.6 71.7 54.1 117.5 84.8 39.5 173.1 152.6 76.0 150.4 83.3 72.2 163.3 63.3 37.8 154.4 0.0 0.0 0.0 0.7 0.0 0.1 2.4 4.1 2.8 0.8 0.2 0.0 0.4 0.5 2.4 0.0 0.2 14.1 3.1 0.3 0.5 0.6 0.6 0.4 0.4 0.6 0.6 0.5 0.4 1.0 0.8 1.2 0.0 20.0 0.0 15.9 8.2 3.7 12.2 2.8 0.7 7.7 8.6 2.3 2.8 10.8 0.0 0.0 74.7 3.3 10.7 0.0 2.0 94.1 5.4 5.1 8.8 3.0 166.7 0.4 0.0 162.0 15.1 8.6 6.9 9.5 42.7 12.8 2.7 52.1 0.0 0.2 17.1 10.2 13.7 13.8 68.4 3.1 9.6 1.8 0.0 0.6 0.4 7.2 0.0 0.3 0.4 2.5 0.7 50.2 2.8 3.2 0.1 2.6 0.5 6.6 0.9 15.2 191.1 58.2 31.3 6.5 19.2 10.1 3.4 38.8 6.3 BLM "BS, RECQ2, RECQL3" ENSG00000197299 "BLM RecQ like helicase" P54132 15 90717346-90816166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.7;lymphoid tissue: 7.9;salivary gland: 7.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 18.3;Oligodendrocyte precursor cells: 58.3;Plasma cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005689 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA005689: AB_1845372" "unprognostic (2.77e-1)" "unprognostic (3.82e-3)" "unprognostic (4.03e-2)" "unprognostic (2.98e-2)" "unprognostic (4.75e-2)" "unprognostic (9.89e-2)" "unprognostic (6.12e-5)" "unprognostic (2.82e-2)" "unprognostic (4.55e-3)" "unprognostic (5.24e-3)" "unprognostic (1.80e-3)" "unprognostic (9.12e-2)" "unprognostic (1.55e-15)" "unprognostic (6.53e-3)" "unprognostic (6.55e-2)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" 0.3 0.2 0.9 3.6 1.1 5.7 0.5 2.3 0.9 0.1 0.3 1.4 1.0 0.4 0.4 0.6 0.3 0.3 0.3 0.8 1.1 0.1 0.1 0.4 6.4 1.2 1.4 0.1 0.2 0.0 0.6 1.2 1.1 0.1 1.7 2.4 7.8 0.0 0.5 0.4 1.6 0.4 1.0 1.6 1.1 2.2 0.9 7.9 0.3 0.1 6.2 1.0 0.2 1.0 13.0 14.4 20.4 12.6 0.1 0.9 14.6 9.4 3.2 11.1 13.4 11.7 10.1 35.1 5.9 2.6 14.1 20.4 25.7 7.1 15.1 19.1 20.5 36.4 14.8 3.9 0.0 33.7 17.3 0.3 0.1 10.6 4.7 1.3 7.9 16.9 32.7 9.9 11.0 7.4 28.3 14.5 22.2 24.9 4.2 25.4 39.1 14.7 2.3 18.9 14.6 14.7 8.5 11.5 4.8 18.1 7.2 23.4 3.7 8.6 13.6 9.6 21.0 6.4 30.4 39.5 5.6 25.8 15.7 1.7 0.6 2.6 1.6 0.8 2.6 4.6 1.4 2.1 0.7 2.3 1.0 1.1 0.7 3.1 1.0 0.7 3.2 0.9 0.9 1.1 2.3 0.9 0.8 1.1 1.2 1.4 1.1 1.0 0.9 1.0 0.9 3.2 8.9 1.0 12.9 0.3 0.5 0.5 0.6 3.6 1.3 1.0 7.9 0.0 4.2 0.0 2.1 5.5 6.9 2.2 1.9 1.0 2.7 1.3 1.3 2.0 0.0 18.3 0.7 0.7 6.8 1.8 3.6 1.7 13.3 8.1 2.2 0.6 5.7 0.0 8.6 1.3 0.0 7.7 1.3 1.6 0.0 7.7 0.0 7.5 2.7 1.7 10.3 58.3 2.6 1.2 0.3 0.4 20.6 0.7 0.2 0.0 5.4 7.1 0.0 0.9 1.7 17.1 12.9 2.2 0.6 1.0 10.2 0.7 4.0 0.4 BLOC1S3 "BLOS3, HPS8" ENSG00000189114 "Biogenesis of lysosomal organelles complex 1 subunit 3" Q6QNY0 19 45178784-45216933 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 39.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050111, HPA070609" Approved Approved "Golgi apparatus" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "HPA050111: AB_2681019, HPA070609: " "unprognostic (1.17e-1)" "unprognostic (3.97e-2)" "unprognostic (6.94e-3)" "unprognostic (6.26e-2)" "unprognostic (3.14e-1)" "unprognostic (3.04e-2)" "unprognostic (1.75e-2)" "unprognostic (2.30e-2)" "unprognostic (2.01e-1)" "unprognostic (9.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.89e-9)" "unprognostic (1.92e-2)" "unprognostic (1.93e-1)" "unprognostic (3.29e-1)" "prognostic favorable (6.86e-4)" 6.7 6.3 7.8 5.9 7.8 12.4 5.7 7.0 8.2 5.7 4.4 5.7 5.3 5.6 5.9 6.4 4.7 3.2 5.2 7.5 6.4 5.7 7.8 5.5 7.6 9.3 8.0 5.6 6.1 4.8 4.4 3.9 8.4 5.7 4.3 3.3 5.6 4.5 4.4 13.2 6.7 4.1 6.8 11.0 7.6 7.2 8.1 4.7 4.7 3.4 7.5 6.6 5.9 9.2 10.4 11.6 3.2 8.1 10.8 7.3 9.7 5.1 8.2 9.5 9.8 7.0 6.6 9.0 12.2 11.9 10.8 16.0 8.5 11.6 6.8 7.9 17.3 12.3 5.5 8.0 15.4 6.0 19.5 10.8 16.3 12.3 17.3 5.4 10.6 5.9 13.2 18.2 5.6 17.8 6.2 9.2 1.8 14.9 14.5 8.9 4.3 7.5 7.0 13.2 6.3 6.0 13.6 22.8 5.1 5.6 9.4 11.1 5.7 9.7 5.5 10.4 8.2 12.7 14.0 6.1 10.6 11.1 7.5 51.1 34.4 30.2 37.4 42.8 31.0 18.4 31.6 28.3 21.4 24.8 25.5 25.5 35.2 24.2 39.9 18.5 29.8 17.8 7.8 7.8 7.0 8.2 7.5 6.4 9.3 8.0 8.4 6.8 8.1 9.2 3.4 0.0 1.7 1.0 5.4 12.7 2.6 1.7 2.2 5.7 4.2 3.2 2.3 1.5 1.5 3.7 0.0 3.7 5.9 4.6 1.9 4.4 17.7 1.9 3.2 5.2 7.2 1.7 2.7 3.7 4.0 3.2 2.0 2.7 8.2 3.0 6.1 6.3 6.1 5.0 2.8 5.0 0.0 8.8 8.9 39.3 6.2 4.7 3.6 1.0 6.8 3.4 11.3 3.5 2.9 5.1 3.2 7.9 4.0 4.9 4.6 4.2 1.7 2.0 0.0 1.9 3.1 1.5 5.1 2.7 13.9 4.5 6.7 3.0 4.1 1.9 BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 23.0;Hepatic stellate cells: 16.8;Inhibitory neurons: 22.8;Microglial cells: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 37.0;HUVEC TERT2: 149.6;Karpas-707: 81.6;SiHa: 70.0;TIME: 74.3;U-266/84: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" 16.5 3.1 5.1 2.2 5.9 0.4 12.7 3.9 6.2 3.2 7.8 3.7 3.0 3.5 0.6 2.0 2.4 2.1 5.1 3.9 3.7 17.8 1.9 9.1 1.5 4.9 4.5 8.2 0.6 0.6 4.6 18.1 4.7 2.8 2.7 0.1 2.3 2.6 3.1 3.5 3.0 2.3 4.8 4.6 4.7 2.2 5.7 0.9 1.5 1.3 2.4 3.3 3.0 4.1 0.9 2.4 0.3 0.0 0.4 0.3 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 37.0 1.1 1.6 0.5 1.1 0.2 0.0 0.0 5.7 15.9 21.8 1.4 0.8 1.1 16.7 0.0 0.0 0.7 2.4 9.6 149.6 0.0 0.0 81.6 0.0 0.3 0.0 0.0 0.8 0.5 12.0 0.6 0.0 15.3 0.5 0.0 12.3 0.0 70.0 0.0 0.0 9.3 0.0 0.0 74.3 0.0 4.7 0.5 2.6 11.3 41.3 0.1 2.3 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.1 5.9 3.9 6.2 3.9 3.7 4.9 4.5 4.7 4.8 5.7 4.1 23.0 0.0 0.5 1.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3.5 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.8 0.2 8.9 0.0 0.0 7.8 0.0 0.1 2.0 0.0 2.0 0.0 1.5 16.8 0.6 0.3 0.0 22.8 0.0 0.0 0.8 2.1 4.2 0.0 1.5 1.8 74.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.8 0.3 0.0 0.0 0.3 0.0 0.0 4.7 0.4 0.1 1.3 0.1 0.1 0.3 0.4 0.4 0.0 0.0 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "epididymis: 102.6" "Group enriched" "Detected in some" 4 "Endothelial cells: 28.2;Hepatic stellate cells: 93.9" "Cancer enhanced" "Detected in many" "melanoma: 3.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Cell line enriched" "Detected in some" 119 "HUVEC TERT2: 353.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 7.7 0.3 0.3 1.7 0.5 7.1 4.9 0.3 0.6 1.7 1.1 3.8 4.4 2.3 102.6 2.3 2.6 2.6 8.8 0.3 0.3 0.6 0.7 3.0 1.5 0.3 0.4 0.9 0.9 0.3 0.2 4.7 0.3 0.9 2.4 0.0 1.1 0.9 1.3 1.6 4.8 2.6 0.3 2.2 1.4 0.2 0.4 0.7 2.0 2.2 0.4 2.6 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 353.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.4 14.1 0.0 1.1 1.3 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.2 0.0 28.2 4.2 3.2 1.3 0.2 0.0 1.1 4.6 0.2 0.0 0.1 93.9 0.7 0.1 0.0 1.2 0.1 2.0 0.0 1.1 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.8 0.0 0.0 0.3 0.8 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.4 0.4 BNIPL "BNIP-S, BNIP-Salpha, BNIP-Sbeta, BNIPl-1, BNIPL-2, PP753" ENSG00000163141 "BCL2 interacting protein like" Q7Z465 1 151036321-151047720 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 128.5;skin 1: 181.4;vagina: 69.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 17.2;Squamous epithelial cells: 42.7;Suprabasal keratinocytes: 57.1;Urothelial cells: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "T-47d: 46.1" "Group enriched" "Detected in some" 9 "basal ganglia: 1.6;cerebellum: 2.4" "Not detected" "Not detected" HPA019946 Uncertain Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA019946: AB_2732424" "unprognostic (2.62e-1)" "unprognostic (7.59e-3)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.50e-4)" "unprognostic (6.58e-2)" "unprognostic (2.82e-2)" "unprognostic (3.32e-3)" "unprognostic (3.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-1)" "unprognostic (3.88e-4)" "unprognostic (1.91e-1)" "unprognostic (8.43e-11)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" "prognostic favorable (4.32e-4)" "unprognostic (6.81e-2)" 0.4 0.3 0.9 0.4 1.0 0.6 15.6 3.0 1.3 25.1 0.7 0.4 0.3 0.3 0.2 128.5 2.7 0.3 0.7 0.9 1.0 2.9 1.2 9.4 0.6 1.5 1.0 0.6 0.4 1.1 0.6 0.5 1.1 12.5 0.2 0.8 22.9 4.7 1.6 181.4 0.5 0.1 0.7 1.1 1.4 4.3 1.0 0.7 7.4 0.1 10.1 9.7 69.7 1.1 0.4 0.4 0.6 0.6 0.4 0.4 0.7 0.3 0.0 0.3 0.2 1.5 0.4 0.7 0.7 0.0 0.1 1.5 0.9 0.2 0.6 1.1 1.0 1.2 0.8 0.2 0.1 0.6 0.6 0.0 3.1 0.2 0.3 1.0 0.0 1.1 0.6 0.5 0.3 2.0 0.7 1.2 0.5 1.0 0.4 0.3 0.3 0.4 0.6 0.4 1.3 0.6 0.5 0.9 0.3 2.2 46.1 0.4 1.1 0.7 0.5 0.2 0.1 1.7 1.3 3.9 0.1 0.3 0.8 0.5 0.1 0.1 0.3 0.1 0.2 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.6 0.1 0.1 0.1 0.0 0.1 0.9 1.0 3.0 1.3 0.9 1.0 1.5 1.0 1.1 0.7 1.0 1.1 0.4 16.0 17.2 0.0 0.3 15.3 6.1 3.9 12.5 0.4 14.2 6.1 0.3 0.0 11.0 11.0 0.0 1.6 1.2 0.3 0.0 0.0 7.6 1.1 1.3 0.8 0.0 0.0 1.1 0.0 0.4 0.9 0.0 1.1 0.0 0.4 2.5 0.1 0.3 0.0 1.2 0.3 2.0 0.6 5.5 1.3 0.9 1.9 3.6 0.0 0.1 0.3 0.0 0.0 0.7 0.0 0.1 0.0 0.6 5.5 0.8 0.3 12.8 1.5 0.0 0.9 1.2 0.9 0.3 42.7 57.1 2.6 1.3 0.2 0.4 24.4 BOLA1 CGI-143 ENSG00000178096 "BolA family member 1" Q9Y3E2 1 149887890-149900798 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal tubular cells: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 49.3;MCF7: 52.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007005 Approved "Intracellular and membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA007005: AB_1078294" "unprognostic (5.73e-2)" "unprognostic (9.86e-3)" "unprognostic (8.84e-2)" "unprognostic (8.18e-2)" "unprognostic (9.33e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.67e-2)" "unprognostic (2.19e-1)" "prognostic favorable (6.41e-4)" "unprognostic (3.14e-3)" "unprognostic (3.36e-2)" "unprognostic (2.22e-1)" "unprognostic (8.73e-2)" "unprognostic (1.31e-1)" "unprognostic (9.58e-2)" "unprognostic (1.93e-3)" 14.9 21.2 8.6 5.8 9.3 3.9 16.1 9.7 17.9 16.1 7.3 24.0 15.3 17.2 0.9 15.7 15.6 3.7 20.5 8.4 8.2 23.0 26.4 10.0 7.0 9.3 8.0 14.5 19.7 5.5 14.4 2.6 8.4 16.8 1.7 1.1 19.3 7.2 23.2 22.5 15.9 2.0 9.2 16.2 20.3 9.9 9.3 5.3 15.8 5.0 1.4 19.0 13.8 10.8 16.4 21.3 2.0 4.2 1.2 4.1 4.0 6.7 1.7 5.0 4.1 15.2 22.0 2.1 16.6 2.8 2.3 17.9 0.0 3.5 0.2 22.8 8.2 1.1 6.1 2.4 7.7 0.0 16.8 3.8 7.3 1.5 0.5 2.0 6.0 49.3 9.1 5.4 2.7 52.9 21.1 5.3 1.3 14.7 6.1 16.4 1.2 4.4 2.3 2.1 13.5 14.8 8.8 14.5 15.9 1.7 26.9 4.5 2.5 6.4 10.5 14.6 0.2 29.5 23.3 0.2 9.0 5.1 6.8 8.6 9.4 12.4 14.8 8.1 15.3 16.2 13.5 11.5 9.9 14.6 18.8 18.1 4.6 9.1 5.2 19.2 18.8 9.3 8.6 9.3 9.7 17.9 8.4 8.2 9.3 8.0 8.4 9.2 9.3 10.8 11.9 3.2 9.5 5.5 10.0 4.5 16.3 19.0 10.8 7.3 23.9 30.5 21.1 34.3 11.2 23.9 4.2 20.2 6.3 12.8 68.4 24.6 8.8 12.1 13.6 13.7 12.6 27.1 2.4 19.8 25.3 16.4 19.4 10.4 5.1 13.9 20.7 40.9 17.0 10.1 3.3 22.8 18.3 12.5 3.5 3.5 15.8 6.6 5.4 1.0 10.3 23.5 19.6 2.5 7.5 15.7 17.6 20.7 18.0 23.1 41.5 57.4 14.2 12.3 39.5 10.9 15.7 22.6 16.2 18.4 6.7 14.0 10.1 22.8 21.2 10.0 BPNT1 ENSG00000162813 "3'(2'), 5'-bisphosphate nucleotidase 1" O95861 1 220057482-220090462 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 55.5;Proximal enterocytes: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 183.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048461 Approved Approved "Nuclear speckles" NA NA 420000 "Cluster 44: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "Nuclear speckles" "HPA048461: AB_2680404" "unprognostic (6.42e-2)" "unprognostic (4.69e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (5.19e-3)" "unprognostic (7.65e-2)" "unprognostic (2.07e-2)" "unprognostic (3.00e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (6.69e-2)" "unprognostic (2.87e-1)" "prognostic favorable (6.38e-4)" "unprognostic (1.82e-2)" "unprognostic (6.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" 16.2 20.8 6.5 18.2 7.8 4.6 20.3 7.5 9.1 18.1 7.3 37.7 43.9 13.9 13.0 14.7 17.6 21.2 17.7 7.3 6.8 31.5 25.0 17.6 34.2 7.6 6.8 17.9 7.7 21.5 10.9 13.2 7.1 13.8 32.2 15.5 17.3 11.9 9.3 10.3 45.7 18.3 7.5 14.6 19.7 14.8 6.7 17.7 20.8 11.3 44.3 15.8 9.9 10.0 37.5 30.3 22.1 17.5 40.6 33.3 35.4 48.0 25.0 42.9 38.3 40.1 70.7 183.9 64.8 33.2 19.1 26.1 45.8 42.3 34.5 68.8 51.2 33.3 34.6 48.3 23.8 90.4 29.9 31.8 20.7 61.0 25.3 28.0 35.9 54.1 62.3 18.4 43.4 21.2 51.9 24.3 18.9 32.0 37.1 36.5 62.9 54.0 55.5 49.2 40.2 33.6 60.1 71.5 43.0 22.1 56.5 31.7 54.2 25.4 19.5 36.7 60.8 31.3 81.6 85.0 22.0 33.6 56.8 20.6 9.2 6.1 12.3 10.0 9.4 20.8 12.8 12.7 10.9 16.5 15.0 11.2 1.1 14.0 9.9 13.3 14.6 9.7 6.5 7.8 7.5 9.1 7.3 6.8 7.6 6.8 7.1 7.5 6.7 10.0 9.3 28.9 23.9 3.6 12.7 3.3 12.5 22.0 3.4 13.7 9.1 6.2 10.5 11.5 23.4 14.7 10.4 13.1 11.6 55.5 13.7 18.7 2.5 10.3 7.7 7.7 19.2 5.5 8.4 15.6 14.1 7.8 7.7 9.7 3.8 12.1 7.9 12.6 9.8 6.7 10.8 14.5 32.6 7.5 3.6 3.1 9.6 7.2 10.6 1.9 8.0 10.8 15.5 10.1 13.0 18.9 28.5 13.5 10.3 6.3 56.9 29.5 14.5 12.0 13.1 5.6 8.7 15.5 11.8 8.2 5.1 25.2 9.6 25.0 17.2 12.7 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 3.1;testis: 2.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 115.4;Spermatogonia: 85.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA026815: AB_10602692" "unprognostic (9.36e-2)" "unprognostic (2.50e-1)" "unprognostic (4.50e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.97e-3)" "unprognostic (4.06e-2)" "unprognostic (3.07e-9)" "unprognostic (2.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.0 1.3 0.0 5.8 0.5 0.0 0.0 0.2 0.2 0.7 0.5 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.3 0.3 2.1 0.1 0.1 0.1 0.1 0.0 0.0 1.0 0.1 0.1 0.8 0.0 0.2 0.0 0.0 0.7 0.5 0.3 0.1 0.9 0.6 2.7 0.2 3.1 0.2 0.0 2.0 0.5 0.2 0.1 4.7 4.0 6.0 5.0 0.6 1.4 7.0 4.8 3.1 5.5 5.0 10.6 6.0 15.9 3.2 2.1 7.6 6.1 5.5 2.9 10.5 10.5 3.1 10.3 2.5 3.5 0.1 15.4 4.9 0.2 0.0 10.3 6.9 0.4 4.5 8.1 7.0 5.5 6.4 5.1 11.8 8.3 8.3 4.9 2.3 11.4 17.3 3.0 1.4 5.4 2.4 4.6 5.9 2.4 2.2 2.2 2.9 7.3 1.3 6.3 6.8 7.0 6.7 2.0 3.3 8.0 2.7 5.7 5.8 0.0 0.3 1.5 0.5 0.7 0.1 1.7 0.4 0.4 0.3 2.2 0.5 0.4 0.8 0.5 0.8 3.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.1 4.4 9.6 2.6 0.0 12.4 2.5 3.3 2.5 2.2 0.0 4.3 3.3 1.9 0.0 1.8 0.0 0.0 14.1 10.5 4.8 0.0 2.5 5.2 4.4 6.3 5.5 1.2 29.5 0.7 1.6 12.7 5.8 10.7 4.6 3.8 26.9 1.4 0.8 9.5 0.0 0.5 4.4 0.0 7.5 11.0 4.4 2.1 14.4 3.6 4.7 20.1 0.3 0.0 0.0 0.6 1.2 1.8 1.2 27.8 1.2 1.0 0.6 2.9 0.0 13.1 8.3 5.3 115.4 85.6 8.0 1.3 5.5 7.9 4.2 7.8 2.3 BRD1 "BRL, BRPF2" ENSG00000100425 "Bromodomain containing 1" O95696 22 49773283-49827512 "Predicted intracellular proteins" "Erythrocyte maturation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000807, HPA001063" Enhanced Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA000807: AB_1078298, HPA001063: AB_1078297" "unprognostic (1.96e-1)" "unprognostic (2.99e-2)" "unprognostic (1.07e-1)" "unprognostic (5.11e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "unprognostic (2.18e-2)" "unprognostic (9.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.28e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-3)" "unprognostic (5.87e-2)" "unprognostic (7.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.26e-1)" "unprognostic (3.95e-3)" 11.4 7.3 3.1 8.1 3.0 15.0 10.8 12.0 5.0 12.5 3.6 14.7 11.7 15.8 2.8 12.8 13.7 7.7 7.5 3.4 3.2 5.4 6.9 10.0 9.4 3.2 2.8 16.0 13.2 8.5 11.2 8.3 2.9 8.7 5.8 6.1 12.1 8.0 16.7 23.2 12.0 6.7 1.5 12.0 11.5 30.7 3.2 14.0 10.2 8.9 7.6 11.8 12.3 4.5 12.7 12.7 22.8 12.8 9.2 8.2 19.3 13.7 9.3 14.2 11.1 19.3 8.3 13.3 7.9 11.4 5.2 17.9 14.7 9.8 6.1 13.4 26.6 13.2 20.3 11.8 17.8 30.5 18.2 12.2 15.1 8.3 10.5 10.3 10.4 15.9 15.3 14.3 7.3 20.8 23.0 15.9 15.7 9.4 10.1 33.6 19.9 13.9 5.5 18.2 14.6 25.8 17.6 22.7 18.4 10.5 10.6 24.9 12.9 13.1 14.1 9.9 12.7 16.8 4.3 18.9 9.3 10.7 11.8 0.3 0.6 0.7 0.5 0.2 1.0 0.4 0.8 1.0 0.4 0.7 0.8 1.0 0.6 0.8 2.9 0.9 0.3 0.5 3.1 3.0 12.0 5.0 3.4 3.2 3.2 2.8 2.9 1.5 3.2 4.5 25.9 22.4 27.6 16.3 13.8 15.8 5.7 7.1 8.6 26.6 14.0 14.7 8.4 5.7 12.7 3.7 29.2 6.7 76.8 13.3 0.0 6.7 7.5 32.4 37.1 13.9 16.2 8.2 25.3 9.3 6.6 17.2 14.8 47.7 10.1 28.3 14.3 12.3 6.7 33.7 22.2 13.9 4.1 13.3 14.0 6.7 11.8 15.4 12.4 16.9 11.2 13.8 7.2 19.1 21.9 9.5 8.7 13.9 43.1 9.1 10.6 3.2 11.3 36.1 0.0 25.4 20.1 42.6 19.7 10.7 18.5 10.1 40.6 26.4 11.3 9.0 BRI3BP "BNAS1, HCCR-2, HCCRBP-3, KG19" ENSG00000184992 "BRI3 binding protein" Q8WY22 12 124993645-125031231 "Predicted membrane proteins, Transporters" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 20.8" "Cell type enhanced" "Detected in many" "Late spermatids: 174.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 114.9;U-698: 161.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014957 Approved Approved Nucleoplasm,Mitochondria NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA014957: AB_1845447" "unprognostic (1.62e-2)" "unprognostic (6.82e-2)" "unprognostic (1.53e-2)" "unprognostic (9.95e-2)" "unprognostic (4.66e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.65e-3)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (7.40e-2)" "unprognostic (4.82e-2)" "unprognostic (2.72e-3)" "unprognostic (1.44e-3)" "unprognostic (2.20e-1)" "unprognostic (9.20e-2)" "unprognostic (1.55e-1)" 3.3 2.0 9.2 8.9 10.7 5.5 5.5 8.2 10.7 3.0 7.1 15.5 20.8 2.1 2.2 6.8 4.1 4.8 2.5 9.2 7.9 6.9 4.8 2.8 13.8 9.6 9.7 1.5 5.1 9.1 2.1 2.1 10.2 2.9 15.3 10.0 2.5 2.2 1.7 5.5 18.8 2.6 9.1 5.9 8.2 1.8 9.1 7.0 4.4 2.1 16.2 2.5 2.6 9.4 34.1 43.8 13.8 12.5 10.9 5.6 24.1 22.2 4.6 13.7 7.1 36.1 22.3 114.9 27.8 5.0 8.9 38.7 30.7 17.3 10.9 26.9 25.5 58.4 16.9 24.8 2.2 86.8 72.2 2.5 9.9 15.0 7.1 5.3 5.1 41.0 23.5 8.0 12.0 31.3 45.1 33.3 9.9 29.9 17.3 30.2 23.0 30.7 17.3 46.8 19.0 13.2 27.6 26.9 9.2 4.6 48.8 60.8 5.9 13.0 16.2 12.5 23.4 26.9 49.7 161.8 11.9 28.7 29.1 4.2 2.2 13.1 0.8 1.6 0.8 1.4 0.6 0.7 1.7 1.5 0.5 0.7 2.2 0.9 1.2 4.2 0.7 0.6 9.2 10.7 8.2 10.7 9.2 7.9 9.6 9.7 10.2 9.1 9.1 9.4 3.4 9.6 10.4 13.4 23.6 12.2 9.1 8.2 5.2 37.1 14.9 6.3 7.2 31.5 9.2 9.2 14.6 15.4 24.3 65.5 3.9 9.1 25.6 16.1 7.2 5.1 7.8 21.5 32.6 10.4 24.0 7.1 32.1 18.0 18.4 7.2 4.2 27.4 19.8 25.2 43.8 42.8 8.2 31.5 26.1 174.4 1.2 23.6 10.6 11.2 28.8 12.1 9.2 11.1 23.4 17.1 43.3 4.1 39.5 9.6 60.2 12.7 15.0 27.9 0.0 9.2 6.9 1.1 11.5 20.7 18.3 5.2 11.5 6.8 72.6 9.7 BSPRY FLJ20150 ENSG00000119411 "B-box and SPRY domain containing" Q5W0U4 9 113349541-113371233 "Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 447.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 61.9;Ductal cells: 66.8;Exocrine glandular cells: 65.8;Pancreatic endocrine cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 21 "dendritic cells: 4.4" "Cell line enhanced" "Detected in many" "A-431: 41.8;CAPAN-2: 25.9;MCF7: 62.0;OE19: 70.9;RPMI-8226: 32.3;SK-BR-3: 29.9;T-47d: 30.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 3.8" "HPA042889, HPA077485" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm Cytosol "HPA042889: AB_10795515, HPA077485: " "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "unprognostic (1.18e-1)" "unprognostic (2.20e-3)" "unprognostic (1.68e-1)" "unprognostic (2.10e-3)" "unprognostic (4.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (2.28e-1)" "unprognostic (1.95e-2)" "prognostic favorable (4.56e-14)" "unprognostic (1.15e-3)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.70e-1)" 0.3 3.1 3.7 2.6 11.3 5.9 14.6 5.9 4.2 6.5 1.2 12.0 8.8 1.1 10.9 30.1 4.4 4.4 1.5 2.5 3.0 14.4 0.8 5.6 0.8 2.1 4.8 0.0 41.7 447.2 8.3 1.7 1.7 5.0 11.0 6.9 81.6 4.5 0.0 26.3 7.0 0.7 1.7 0.5 24.7 2.8 5.9 1.8 30.3 0.1 3.1 3.0 7.6 2.5 41.8 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 8.6 25.9 0.0 0.4 0.0 0.0 3.6 0.4 0.0 0.0 4.6 3.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.8 0.3 0.0 0.0 62.0 0.7 0.0 1.0 70.9 0.0 0.9 0.0 32.3 4.0 8.8 13.7 0.0 0.0 29.9 0.0 1.7 30.3 4.3 0.0 0.0 0.0 0.1 0.0 9.7 13.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.4 0.0 0.0 3.7 11.3 5.9 4.2 2.5 3.0 2.1 4.8 1.7 1.7 5.9 2.5 0.3 6.4 6.9 0.0 2.5 1.0 2.0 4.4 0.0 1.8 61.9 31.2 2.8 17.2 9.5 27.6 6.2 9.2 9.9 20.8 39.2 66.8 0.5 11.3 1.6 0.9 20.4 15.6 1.0 65.8 1.1 0.7 21.4 17.3 3.8 1.5 0.0 0.8 1.4 0.0 3.2 19.1 12.2 0.3 0.3 0.6 0.0 0.5 10.6 0.0 1.0 0.8 3.1 0.5 0.2 48.6 14.5 0.0 2.5 13.8 13.5 21.2 9.7 12.1 0.0 0.0 1.7 0.6 4.3 26.4 14.2 6.7 1.3 0.1 24.9 17.7 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.8;Macrophages: 33.3;monocytes: 80.1;Proximal enterocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Cell line enhanced" "Detected in many" "THP-1: 76.0;TIME: 40.4;U-937: 52.5;WM-115: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 21.2 2.7 1.9 13.7 2.1 139.8 9.4 2.1 4.7 11.0 1.6 8.3 48.6 6.3 2.9 4.6 7.9 18.2 19.1 2.1 2.0 17.0 8.5 12.7 7.1 1.9 1.4 9.3 3.1 1.7 1.3 13.7 2.2 3.7 9.7 1.0 3.9 4.6 2.7 5.0 29.3 9.7 0.8 18.6 3.2 2.7 3.0 3.9 4.9 6.8 3.5 16.8 7.4 3.3 0.6 10.5 1.2 1.0 28.8 7.0 1.6 21.0 2.1 20.4 22.2 0.3 12.1 0.8 1.9 12.2 0.6 0.3 3.3 0.5 17.2 0.8 0.7 5.6 0.8 0.6 6.7 7.2 15.1 5.7 1.5 12.9 1.0 0.9 3.0 5.0 0.7 0.5 12.5 0.3 2.3 4.3 2.7 0.9 2.2 0.8 1.8 0.5 0.5 0.6 1.4 4.3 0.4 0.7 14.2 1.2 0.5 76.0 40.4 0.6 1.0 7.9 1.1 0.6 0.2 0.7 2.7 52.5 44.8 41.8 257.7 20.8 1.1 97.4 1.7 2.2 0.9 0.8 78.9 0.9 1.1 0.7 292.7 0.4 73.9 26.6 1.0 109.8 1.9 2.1 2.1 4.7 2.1 2.0 1.9 1.4 2.2 0.8 3.0 3.3 5.4 3.2 3.7 1.3 0.3 4.6 0.8 0.1 1.8 0.6 1.2 2.0 1.5 2.8 1.0 1.8 0.0 16.0 5.5 3.7 1.9 4.4 4.4 8.0 9.9 3.8 1.2 2.5 0.7 2.5 24.0 22.5 0.0 16.2 15.9 20.6 6.4 2.1 40.8 0.0 0.7 8.1 0.0 26.3 11.5 1.2 3.1 33.3 14.2 3.7 80.1 0.6 3.1 0.5 3.6 1.1 11.9 2.2 0.4 0.6 79.0 9.6 3.0 0.2 6.6 3.9 15.5 2.5 1.4 1.7 3.0 7.1 1.8 1.4 23.2 3.3 BTBD11 "ABTB2B, FLJ33957" ENSG00000151136 "BTB domain containing 11" A6QL63 12 107318421-107659642 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 100.3" "Cell type enriched" "Detected in many" 9 "Inhibitory neurons: 266.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 25.0;Hep G2: 13.6;MOLT-4: 17.9;PC-3: 12.3;RT4: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055898, HPA061334" Supported Nucleoplasm,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA055898: AB_2682964, HPA061334: " "unprognostic (3.40e-2)" "unprognostic (4.06e-1)" "unprognostic (2.37e-1)" "unprognostic (7.85e-2)" "unprognostic (8.78e-3)" "unprognostic (4.82e-2)" "unprognostic (3.52e-1)" "unprognostic (2.12e-1)" "unprognostic (1.52e-1)" "unprognostic (5.92e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.92e-8)" "unprognostic (2.66e-1)" "unprognostic (1.55e-1)" "unprognostic (3.33e-2)" "unprognostic (9.07e-3)" 0.4 0.7 7.2 2.7 4.3 4.4 2.9 5.5 10.9 8.1 5.9 0.6 0.7 0.9 1.2 29.4 0.3 0.9 0.6 2.9 13.2 4.2 1.1 0.6 2.9 24.3 16.0 0.1 0.8 100.3 3.5 2.0 24.4 3.4 0.6 1.9 5.6 1.3 0.5 11.1 1.4 0.5 11.4 1.4 0.6 0.7 21.7 17.2 18.9 0.2 3.3 1.7 11.1 5.3 0.1 25.0 5.0 0.0 1.8 0.5 0.0 0.6 0.0 0.2 0.0 0.3 4.0 0.0 6.1 0.1 2.4 9.2 5.1 9.5 0.3 0.0 1.6 0.0 0.1 13.6 0.0 0.2 0.1 2.0 4.0 0.0 2.9 3.8 0.7 10.5 0.0 0.0 0.2 0.9 17.9 2.0 5.3 0.5 12.3 0.0 8.1 0.0 0.0 11.4 6.8 2.5 0.0 0.2 0.0 0.4 0.5 0.7 1.0 0.1 0.2 0.0 2.0 0.1 0.0 0.1 6.4 2.6 0.0 0.9 0.4 0.5 1.0 0.1 3.5 0.0 1.1 0.6 0.7 0.1 1.4 1.3 1.3 0.1 0.3 0.1 0.6 0.6 7.2 4.3 5.5 10.9 2.9 13.2 24.3 16.0 24.4 11.4 21.7 5.3 0.3 0.0 0.0 17.3 0.3 5.2 3.7 2.5 6.8 3.5 0.7 3.2 2.9 0.0 3.0 0.0 0.0 0.2 1.2 0.0 0.0 0.8 0.0 1.2 1.9 0.3 3.5 1.3 8.7 0.0 0.0 1.5 0.0 2.3 0.0 0.0 0.0 0.9 0.3 1.7 266.4 0.4 0.0 0.6 4.3 0.0 0.6 1.7 0.0 1.0 1.8 0.2 3.1 12.5 1.9 0.3 0.0 4.1 0.7 2.8 0.2 0.9 0.3 0.4 0.0 0.0 1.1 0.1 0.2 27.5 7.7 0.4 4.5 3.4 0.4 3.4 BTBD16 "C10orf87, Em:AC061711.1, FLJ25359" ENSG00000138152 "BTB domain containing 16" Q32M84 10 122271296-122338159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 8.3;testis: 7.8;urinary bladder: 20.2" "Group enriched" "Detected in some" 9 "Early spermatids: 123.2;Late spermatids: 69.9" "Cancer enriched" "Detected in many" 14 "urothelial cancer: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "RT4: 33.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA040529, HPA057638" Uncertain Uncertain Nucleoli,Cytosol Yes NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" Nucleoli Cytosol "HPA040529: AB_2677022, HPA057638: " "unprognostic (1.41e-4)" "unprognostic (1.33e-1)" "unprognostic (5.97e-2)" "unprognostic (5.98e-3)" "unprognostic (2.08e-1)" "unprognostic (2.09e-3)" "unprognostic (2.88e-1)" "unprognostic (4.54e-2)" "unprognostic (1.76e-1)" "unprognostic (6.85e-2)" "unprognostic (2.48e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (9.12e-2)" "unprognostic (9.44e-3)" 0.1 0.0 1.0 0.0 1.4 0.0 0.5 1.2 2.3 0.3 0.7 0.5 0.0 0.1 0.3 0.1 0.4 0.2 0.0 1.1 1.2 0.3 4.0 0.2 0.0 1.4 1.4 0.0 0.1 0.0 0.4 0.1 1.4 0.8 0.0 0.0 0.4 0.0 0.3 8.3 0.1 0.1 1.3 0.0 0.1 7.8 1.2 0.0 0.4 0.0 0.1 20.2 0.5 2.1 0.0 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 1.5 33.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 1.4 1.2 2.3 1.1 1.2 1.4 1.4 1.4 1.3 1.2 2.1 0.0 0.0 0.0 0.0 0.0 2.8 0.4 0.2 0.0 0.0 0.2 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 1.4 123.2 0.6 0.0 0.2 0.0 0.0 0.9 0.7 0.1 0.0 0.0 0.4 0.0 0.0 0.0 4.5 0.0 0.0 1.2 0.0 0.0 0.0 0.4 69.9 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.5 9.8 1.1 3.8 0.4 0.0 0.1 0.2 1.0 3.1 0.0 0.0 0.4 0.2 10.0 0.8 0.0 3.1 0.1 0.4 0.0 0.0 2.9 BTC ENSG00000174808 Betacellulin P35070 4 74744759-74794523 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.5;Respiratory ciliated cells: 43.1;Skeletal myocytes: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 16.1;MCF7: 5.8;RPTEC TERT1: 9.5;SK-BR-3: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 314000 "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (7.36e-2)" "unprognostic (4.99e-2)" "unprognostic (7.04e-2)" "unprognostic (7.76e-3)" "unprognostic (3.87e-3)" "unprognostic (1.01e-3)" "unprognostic (1.05e-1)" "unprognostic (7.17e-3)" "unprognostic (2.68e-2)" "unprognostic (8.81e-2)" "unprognostic (1.50e-2)" "unprognostic (5.35e-1)" "prognostic favorable (6.10e-5)" "unprognostic (2.33e-1)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (2.31e-3)" 2.5 1.7 0.6 1.8 0.8 0.0 4.1 0.2 0.9 2.7 3.9 25.6 4.3 3.2 6.9 11.0 7.6 6.2 0.4 0.9 0.7 4.4 1.1 4.6 0.1 1.0 1.3 0.9 2.9 7.3 1.6 0.4 0.8 4.6 7.4 4.2 6.9 4.4 0.4 13.7 6.8 10.0 0.9 0.1 6.2 0.6 0.7 0.2 5.8 1.0 0.5 4.6 1.9 0.7 3.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 1.1 0.0 16.1 0.0 3.3 0.0 2.3 0.5 0.0 0.1 0.0 0.0 0.3 0.1 0.6 0.0 0.2 0.0 0.0 0.0 1.2 0.3 0.1 2.6 0.1 0.0 0.0 0.1 0.4 5.8 0.1 0.0 0.0 1.7 2.4 0.0 0.0 0.0 9.5 4.6 0.2 0.0 2.4 6.4 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.3 2.8 0.3 0.0 0.0 2.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.8 0.2 0.9 0.9 0.7 1.0 1.3 0.8 0.9 0.7 0.7 2.9 9.6 10.8 0.0 0.0 0.6 3.9 3.7 0.0 2.4 3.9 1.4 0.9 4.3 12.2 11.0 2.1 0.5 0.0 6.1 0.0 4.1 2.0 18.5 1.3 0.7 12.0 0.0 7.7 5.9 0.0 0.7 8.6 10.7 0.0 6.7 2.9 0.4 0.1 0.0 3.2 9.9 10.2 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 10.4 0.0 2.5 0.3 3.3 4.9 0.0 0.0 4.3 1.7 1.1 43.1 5.7 0.0 18.5 5.6 0.0 0.2 8.4 3.0 0.3 0.2 1.2 7.3 7.6 BTG1 APRO2 ENSG00000133639 "BTG anti-proliferation factor 1" P62324 12 92140278-92145846 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2751.6;Langerhans cells: 2893.3;Suprabasal keratinocytes: 3004.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 33.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005972 Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA005972: AB_1078303" "prognostic favorable (4.36e-5)" "unprognostic (1.43e-1)" "unprognostic (2.32e-1)" "unprognostic (1.37e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-3)" "unprognostic (1.10e-1)" "unprognostic (5.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (2.50e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.95e-7)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (5.79e-2)" "unprognostic (9.81e-2)" 91.5 36.9 1.9 19.8 2.0 93.9 80.1 33.5 4.1 62.3 1.4 38.9 8.5 45.6 1.5 29.5 55.9 7.1 45.2 2.5 4.6 52.4 69.7 55.5 23.8 3.6 2.6 45.6 63.7 8.3 26.2 6.2 3.7 40.5 4.8 5.2 30.5 4.5 20.5 120.6 58.4 8.2 3.5 92.2 39.3 12.4 3.1 20.1 21.9 3.7 18.2 38.5 60.1 3.0 5.7 5.4 3.5 0.9 13.4 16.9 3.2 8.0 6.3 2.3 2.3 2.4 1.6 5.7 1.5 3.3 3.5 3.9 1.6 3.0 2.2 9.8 8.8 0.8 2.9 1.3 15.0 3.7 1.9 14.1 11.9 4.5 11.7 8.5 5.0 2.4 4.6 7.1 3.4 3.7 5.5 9.4 2.2 3.0 11.0 15.2 2.4 1.5 5.5 6.5 3.4 7.8 6.1 4.4 17.3 2.1 21.5 7.7 2.6 3.9 1.3 3.6 3.7 14.0 6.3 8.9 3.1 2.4 4.6 36.2 21.8 151.8 22.8 16.2 27.8 92.4 47.3 40.7 9.2 105.5 133.1 53.6 75.9 68.8 22.8 8.0 66.8 51.3 1.9 2.0 33.5 4.1 2.5 4.6 3.6 2.6 3.7 3.5 3.1 3.0 1186.6 96.1 185.4 12.1 2512.8 2751.6 1030.9 206.6 912.9 592.7 607.5 573.8 119.5 1009.4 140.4 174.7 196.0 412.8 1907.2 672.9 320.8 388.1 411.8 216.7 258.8 709.0 452.4 230.7 7.9 255.8 416.3 529.1 406.7 264.7 286.6 197.4 339.1 274.9 361.4 424.0 20.6 373.8 193.3 564.3 2893.3 213.7 287.1 1251.4 983.6 31.9 1241.2 877.6 1354.3 22.1 8.4 364.4 668.7 241.9 758.5 791.3 667.9 162.6 53.0 377.2 539.0 870.7 723.5 130.1 101.5 508.7 3004.2 1342.7 2354.0 786.4 410.9 1513.3 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637528-110678063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 11.9;lymphoid tissue: 27.5;testis: 30.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.8;Granulosa cells: 66.1;Plasma cells: 35.2;Spermatocytes: 85.6;Spermatogonia: 20.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 221.5" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (1.03e-5)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 0.5 0.4 0.1 8.4 0.3 11.9 1.2 0.1 0.1 0.9 0.0 4.3 4.0 1.0 3.5 4.7 0.5 0.9 0.6 0.1 0.1 0.3 0.6 1.2 15.9 0.1 0.6 0.4 0.2 0.7 0.0 3.2 0.3 0.3 5.7 0.1 0.9 0.1 0.1 2.7 3.5 2.2 0.0 5.6 1.9 30.3 0.4 27.5 0.4 0.2 17.0 2.4 1.6 0.3 96.0 29.4 68.5 46.8 3.8 5.3 38.8 50.9 32.9 85.6 62.3 58.3 55.0 64.7 30.9 30.1 80.1 43.2 93.9 35.0 105.7 51.4 45.6 221.5 26.2 50.6 0.8 63.5 57.0 1.7 2.8 65.2 33.1 12.7 49.8 73.2 96.8 126.5 76.8 33.7 126.3 39.0 71.2 39.4 55.3 69.3 64.2 102.7 18.3 27.0 48.3 21.4 34.2 31.4 27.2 44.1 24.0 60.6 19.1 39.7 57.5 28.8 69.0 67.3 65.5 75.4 24.2 48.6 69.8 1.1 0.0 0.2 0.2 0.0 0.3 0.5 0.9 0.5 0.1 0.5 0.6 0.4 0.0 0.5 0.0 0.9 1.5 0.3 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.6 0.3 0.0 0.4 0.3 0.2 0.0 1.5 0.0 5.5 0.5 0.5 2.0 0.6 0.0 0.9 0.8 1.1 0.0 1.6 0.0 0.0 5.8 2.5 2.4 0.0 0.3 13.5 4.5 1.5 1.1 0.0 24.8 0.2 0.0 9.8 2.2 2.0 2.2 0.0 66.1 1.8 0.3 8.1 0.0 0.2 3.1 4.1 1.6 1.4 7.5 0.3 2.0 0.0 0.0 0.6 0.0 0.0 0.5 1.0 0.1 0.0 0.4 35.2 0.5 0.3 0.1 1.8 0.0 6.6 0.2 3.7 85.6 20.0 4.0 0.4 0.7 2.9 0.5 5.9 0.9 BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221123 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.8;lymphoid tissue: 35.7;testis: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.5;Spermatocytes: 79.2;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA008419 Supported Cytosol Yes Yes "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA008419: AB_1078308" "unprognostic (4.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.65e-2)" "unprognostic (2.44e-3)" "unprognostic (9.66e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (7.43e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.69e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (1.76e-2)" "unprognostic (0.00e+0)" "unprognostic (3.75e-2)" "unprognostic (4.66e-2)" "unprognostic (2.20e-1)" "unprognostic (3.94e-2)" 0.4 0.5 0.1 6.7 0.1 17.8 1.6 0.3 0.2 1.0 7.7 4.6 4.7 1.2 0.3 5.2 0.6 0.6 0.3 0.3 0.1 0.3 0.4 1.0 12.6 0.0 0.1 0.2 0.2 0.2 0.1 3.4 0.1 0.4 6.0 0.1 0.9 0.2 0.0 3.5 4.1 2.1 0.0 3.1 2.4 22.2 0.2 35.7 0.5 0.0 15.0 1.5 1.7 0.0 66.5 32.8 103.0 41.5 2.5 7.1 33.2 60.9 34.2 64.6 55.7 48.1 25.0 59.7 33.5 22.7 59.0 72.6 98.8 33.2 70.5 51.8 52.1 86.4 83.6 45.5 0.2 79.0 45.7 1.6 2.0 39.2 37.1 12.9 47.7 66.5 76.4 61.7 65.6 22.5 62.5 48.9 70.2 55.6 36.8 66.5 83.7 45.2 19.9 33.1 67.1 40.8 38.0 35.9 13.3 45.1 41.9 40.9 27.6 49.3 51.8 49.2 55.5 32.1 58.2 95.6 26.3 87.8 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 3.2 1.1 0.3 1.8 0.8 0.3 1.0 1.8 0.7 0.9 2.0 0.8 0.0 1.9 0.0 0.0 5.4 0.6 1.8 0.0 0.4 3.0 0.9 1.4 1.0 0.0 23.5 0.7 0.0 6.7 2.4 5.6 2.1 0.0 12.9 1.1 0.3 5.2 0.0 0.7 2.5 0.0 1.9 1.7 3.3 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 1.5 0.4 12.6 0.3 0.3 0.1 0.2 0.2 6.6 0.2 1.7 79.2 26.8 6.9 0.3 0.8 1.8 0.8 5.4 0.6 BZW2 "HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265.5;skeletal muscle: 367.7;tongue: 258.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 278.2;Extravillous trophoblasts: 875.6;Syncytiotrophoblasts: 762.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Cytosol" "HPA022813: AB_1845511, HPA026709: AB_10600752" "unprognostic (2.27e-3)" "unprognostic (1.77e-3)" "unprognostic (5.91e-2)" "unprognostic (4.79e-3)" "unprognostic (2.80e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (7.86e-8)" "unprognostic (9.13e-3)" "unprognostic (8.49e-3)" "unprognostic (2.81e-2)" "unprognostic (1.83e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.00e-1)" "unprognostic (1.66e-1)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" 26.1 18.1 8.5 26.8 10.1 45.7 49.7 6.9 14.3 19.1 9.7 51.2 28.9 18.4 9.9 42.6 20.2 17.2 265.5 10.2 6.3 37.8 18.4 20.0 30.0 5.2 6.3 16.0 30.0 6.7 10.4 80.4 6.5 19.3 56.8 88.0 23.8 34.3 367.7 55.5 30.0 39.0 5.6 16.5 50.2 11.6 6.9 33.0 36.5 258.9 38.4 59.5 26.2 8.8 91.7 81.3 138.2 201.7 67.5 118.3 125.7 126.0 156.3 117.6 124.9 201.8 129.7 208.0 143.7 96.9 87.6 181.6 164.8 141.5 152.0 27.8 99.8 129.6 84.4 117.0 70.5 180.3 79.1 90.6 74.6 104.0 187.7 92.4 171.6 149.7 251.9 43.5 96.9 105.0 90.0 210.4 143.9 259.5 174.1 111.0 91.2 216.6 113.4 152.6 179.9 106.8 50.8 419.9 67.7 156.7 187.8 149.5 97.6 93.1 119.1 141.5 136.3 89.5 92.8 288.1 45.5 220.6 340.3 2.6 46.0 5.0 27.3 55.2 44.6 44.6 39.8 36.9 98.8 42.9 56.8 47.1 2.1 56.8 41.6 38.5 31.8 44.0 8.5 10.1 6.9 14.3 10.2 6.3 5.2 6.3 6.5 5.6 6.9 8.8 32.8 22.4 60.5 3.9 30.0 57.6 69.9 60.5 82.6 55.9 52.3 57.0 278.2 17.2 53.9 47.8 64.6 214.3 26.8 42.4 58.7 47.5 9.8 31.9 43.2 42.9 30.5 63.5 48.6 65.6 875.6 43.5 110.1 40.6 21.0 33.3 8.9 13.7 65.0 6.7 32.0 49.5 61.1 33.4 46.0 6.4 12.2 30.7 24.9 12.2 47.5 19.7 19.6 19.1 17.9 47.0 42.9 9.8 31.9 52.0 19.2 20.8 32.6 106.4 6.6 30.2 54.2 11.3 4.1 99.6 51.6 762.9 29.3 52.6 90.6 79.0 C10orf90 "bA422P15.2, FATS, FLJ32938" ENSG00000154493 "Chromosome 10 open reading frame 90" Q96M02 10 126424997-126798708 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 112.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 819.4" "Cancer enriched" "Detected in some" 5 "melanoma: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SK-MEL-30: 118.8;U-2197: 36.1;U-266/84: 27.2;U-87 MG: 37.0;WM-115: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038648, HPA075229" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA038648: AB_10672721, HPA075229: " "unprognostic (1.21e-2)" "unprognostic (3.34e-1)" "unprognostic (7.50e-2)" "unprognostic (2.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.30e-2)" "unprognostic (1.98e-3)" "unprognostic (5.06e-2)" "unprognostic (9.34e-3)" "unprognostic (3.73e-2)" "unprognostic (9.52e-2)" "unprognostic (1.22e-1)" "unprognostic (5.06e-11)" "unprognostic (2.69e-3)" "unprognostic (9.91e-3)" "unprognostic (1.26e-1)" "unprognostic (2.88e-1)" 0.7 0.0 30.4 0.1 74.4 0.0 4.7 41.9 47.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 29.9 37.4 0.3 0.1 0.0 0.0 60.4 53.8 0.1 0.2 0.0 0.3 0.3 57.0 0.0 0.1 0.0 10.6 0.0 0.1 1.1 0.1 0.0 29.8 0.0 0.0 6.5 68.0 1.1 0.3 0.4 0.7 0.0 0.0 112.1 0.3 0.1 0.0 0.0 0.8 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 2.3 0.0 1.6 0.0 0.9 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 2.6 0.0 0.0 0.0 0.0 118.8 0.0 0.0 0.2 0.0 4.7 0.0 36.1 0.7 0.0 27.2 0.0 37.0 0.0 29.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.4 74.4 41.9 47.7 29.9 37.4 60.4 53.8 57.0 29.8 68.0 112.1 0.2 0.0 0.0 24.5 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 120.5 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.0 142.7 0.3 0.0 0.0 3.7 0.0 0.0 0.0 181.0 819.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 1.3 0.5 0.0 0.0 4.2 0.1 0.0 0.0 0.0 C10orf95 FLJ14280 ENSG00000120055 "Chromosome 10 open reading frame 95" 10 102449837-102451543 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 9.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 30.1;Rod photoreceptor cells: 18.4;Syncytiotrophoblasts: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 11.8;JURKAT: 11.7" "Low region specificity" "Detected in single" "Secreted - unknown location" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.31e-1)" "unprognostic (7.76e-3)" "unprognostic (3.19e-1)" "unprognostic (5.62e-3)" "unprognostic (4.02e-1)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (5.98e-2)" "unprognostic (1.50e-2)" "unprognostic (1.01e-1)" "unprognostic (4.42e-2)" "unprognostic (2.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (2.14e-1)" "unprognostic (1.22e-2)" "unprognostic (4.80e-3)" 0.5 1.5 0.7 1.8 0.6 2.0 0.2 2.8 1.1 1.1 0.9 1.2 2.5 1.2 0.4 1.3 9.7 1.4 0.6 0.6 0.8 1.4 0.4 3.5 2.9 0.3 0.2 1.1 4.7 0.1 1.3 0.7 0.1 1.6 0.4 4.7 4.0 0.1 0.7 4.1 2.3 0.0 0.0 2.6 3.6 0.7 0.9 0.0 5.3 0.0 0.5 0.6 0.5 0.1 5.7 1.1 0.1 2.3 0.0 0.0 4.9 0.2 0.0 0.0 0.0 4.4 9.8 5.0 2.2 0.0 0.7 9.8 0.0 0.4 0.0 4.3 11.8 3.2 4.7 3.7 0.0 4.4 3.0 0.1 1.8 0.0 0.1 3.1 0.0 11.7 5.6 4.1 0.0 4.5 2.4 4.2 2.2 2.0 3.3 7.0 0.1 5.4 1.1 2.0 8.8 1.3 2.4 1.5 3.1 1.7 4.8 0.3 0.4 0.2 1.0 0.2 0.5 3.5 2.9 3.3 0.2 6.5 0.1 2.1 1.2 1.7 7.8 0.6 7.4 10.7 8.4 7.9 3.6 8.3 11.7 9.9 0.9 10.1 0.3 6.3 9.6 4.9 0.7 0.6 2.8 1.1 0.6 0.8 0.3 0.2 0.1 0.0 0.9 0.1 0.3 0.0 3.2 0.7 3.1 1.5 4.3 0.5 0.0 4.6 2.4 2.5 0.1 2.8 4.2 5.5 10.4 2.3 6.4 2.5 3.9 1.5 0.1 30.1 0.7 1.0 1.2 1.3 0.7 1.1 1.7 0.3 1.5 4.0 0.0 0.8 0.4 0.3 2.3 3.3 0.7 3.7 4.1 1.0 1.0 0.5 0.6 1.4 0.0 0.0 2.2 2.7 6.2 0.0 0.0 0.7 0.4 0.7 2.5 3.3 2.0 4.2 8.7 18.4 0.0 0.9 0.5 0.7 1.4 1.9 1.6 38.0 3.2 0.7 3.2 2.9 C11orf24 DM4E3 ENSG00000171067 "Chromosome 11 open reading frame 24" Q96F05 11 68261338-68272001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 107.7;Proximal enterocytes: 162.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 222.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012411, HPA012748" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012411: , HPA012748: AB_1845526" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (1.19e-1)" "unprognostic (8.22e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.31e-2)" "unprognostic (7.91e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.56e-1)" "unprognostic (2.68e-2)" "unprognostic (4.99e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.60e-9)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (8.67e-3)" 25.0 17.6 8.9 20.7 12.2 4.7 21.0 12.1 12.7 23.3 8.2 29.2 53.8 39.2 7.3 15.5 22.2 17.6 31.5 9.7 10.5 17.0 87.4 24.1 15.5 14.4 11.6 19.3 27.3 7.3 14.5 16.1 12.5 22.9 17.4 3.0 34.0 17.6 13.7 15.4 59.4 32.6 11.0 20.8 23.6 14.6 12.8 6.4 17.0 15.2 16.7 22.3 19.4 15.2 44.8 45.5 26.4 51.6 62.1 62.5 29.7 105.4 67.5 51.8 53.1 96.2 26.9 20.1 31.7 131.3 47.2 49.4 39.1 47.4 33.2 22.1 23.1 21.4 44.8 65.3 50.1 18.3 68.7 52.1 34.6 78.8 32.0 31.0 21.2 10.6 37.9 32.2 44.6 55.7 4.5 26.4 44.2 72.1 53.8 8.2 44.8 104.1 23.9 21.1 17.3 31.8 33.3 27.1 222.8 21.8 25.6 15.3 23.3 80.8 50.2 103.3 47.3 39.4 41.4 18.8 65.1 14.1 79.9 16.7 12.1 12.6 14.0 19.0 9.4 26.7 7.9 8.9 19.5 35.7 7.3 7.7 1.8 9.9 14.1 26.7 8.4 12.6 8.9 12.2 12.1 12.7 9.7 10.5 14.4 11.6 12.5 11.0 12.8 15.2 6.8 9.6 3.6 3.3 25.5 14.0 12.2 11.7 9.6 4.8 8.2 8.9 10.4 11.5 6.9 9.2 2.1 11.9 12.4 36.2 1.9 21.9 3.5 5.3 17.8 6.6 4.8 9.1 4.1 31.5 30.7 21.1 18.3 6.8 45.0 5.0 9.3 107.7 15.8 0.0 4.2 50.0 6.1 12.9 23.5 7.1 14.0 12.3 28.4 5.6 14.9 6.8 18.6 6.6 8.5 26.9 16.6 16.1 67.0 13.0 162.5 10.6 9.4 2.9 13.1 11.2 20.2 20.7 27.1 9.6 11.2 10.5 6.5 9.6 15.5 10.6 C11orf49 "FLJ22210, MGC4707" ENSG00000149179 "Chromosome 11 open reading frame 49" Q9H6J7 11 46936689-47164385 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 140.0;Excitatory neurons: 140.8;Inhibitory neurons: 112.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040051, HPA040280" Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "HPA040051: AB_10795412, HPA040280: AB_10795363" "unprognostic (3.11e-2)" "unprognostic (3.01e-1)" "unprognostic (2.15e-1)" "unprognostic (1.06e-2)" "unprognostic (6.65e-2)" "unprognostic (7.76e-2)" "prognostic unfavorable (2.18e-5)" "unprognostic (1.27e-1)" "unprognostic (2.76e-1)" "unprognostic (1.72e-1)" "unprognostic (2.14e-2)" "unprognostic (1.55e-1)" "unprognostic (1.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (5.34e-3)" 8.1 13.4 52.4 6.2 51.6 3.3 10.0 45.9 54.7 15.6 46.1 14.3 11.2 16.8 14.1 9.7 32.5 9.6 12.3 52.4 53.3 15.7 3.9 12.1 6.3 47.0 53.9 14.9 12.7 22.6 30.3 6.8 49.2 12.4 11.4 21.8 11.0 13.2 7.3 31.6 11.9 12.8 46.2 7.0 15.4 20.2 53.7 13.7 16.1 6.4 7.2 11.9 11.4 45.5 10.9 30.6 37.9 27.9 17.8 25.7 9.5 11.7 26.9 24.6 29.9 6.9 17.0 9.1 12.3 24.4 29.7 14.8 18.8 28.7 20.9 18.1 27.2 12.2 36.6 12.6 30.5 14.6 16.2 17.5 19.1 11.2 16.4 47.0 27.6 22.1 10.3 11.7 18.2 22.8 23.0 16.2 14.3 26.5 16.4 8.2 9.5 10.1 43.3 11.7 25.5 36.5 13.4 14.9 14.7 19.7 25.0 8.5 6.5 13.8 11.0 22.0 17.7 10.4 9.2 7.5 33.7 3.0 17.5 12.7 10.2 9.0 19.2 13.7 23.0 24.1 18.1 22.7 24.6 17.6 19.1 20.3 0.3 25.2 10.3 21.8 19.0 18.3 52.4 51.6 45.9 54.7 52.4 53.3 47.0 53.9 49.2 46.2 53.7 45.5 6.6 9.6 26.7 140.0 9.9 13.0 16.4 30.6 12.0 22.9 12.0 13.0 9.4 12.8 24.0 23.9 18.8 19.4 5.6 18.3 46.9 30.2 53.2 42.8 20.4 10.2 19.2 8.0 140.8 20.4 13.4 18.0 25.5 14.1 16.4 23.3 8.6 2.4 9.9 37.0 112.7 12.8 22.4 3.3 7.0 35.8 12.8 6.2 12.4 41.2 10.9 45.0 7.2 93.0 71.9 16.2 21.2 20.3 5.8 8.1 22.1 33.4 66.7 53.1 6.6 12.2 13.5 63.3 7.6 10.5 18.0 10.0 10.8 32.6 13.7 12.1 C12orf66 FLJ32549 ENSG00000174206 "Chromosome 12 open reading frame 66" Q96MD2 12 64186316-64222296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046743, HPA052855" Uncertain Supported "Lysosomes,Cytokinetic bridge" Yes No "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Lysosomes "Cytokinetic bridge" "HPA046743: AB_2679782, HPA052855: AB_2681973" "unprognostic (7.44e-3)" "unprognostic (2.38e-1)" "unprognostic (6.20e-2)" "unprognostic (2.70e-1)" "unprognostic (2.31e-1)" "unprognostic (4.62e-2)" "unprognostic (3.45e-2)" "unprognostic (2.08e-1)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (7.46e-2)" "unprognostic (4.07e-2)" 2.9 4.2 3.6 3.4 5.3 1.7 5.4 4.0 4.8 2.8 1.9 2.8 3.1 2.6 4.8 4.2 3.9 2.5 2.3 3.5 4.3 5.5 8.6 2.8 4.9 4.0 4.4 3.9 5.2 5.7 2.6 2.1 4.5 2.3 3.1 1.6 2.9 2.3 4.4 5.6 2.5 2.3 3.7 5.0 3.0 3.4 4.3 3.3 5.6 3.2 4.8 2.6 3.0 6.8 5.5 8.7 1.6 4.7 4.3 7.2 4.5 3.0 3.7 4.4 2.7 2.7 4.3 17.4 4.1 2.4 7.1 6.3 6.9 5.3 4.7 13.3 4.6 6.3 2.1 2.5 5.6 6.9 3.6 5.6 9.0 5.7 10.3 5.0 3.2 12.0 8.8 11.3 4.4 10.6 7.9 6.0 7.7 6.5 6.8 4.0 4.9 13.4 6.6 6.4 3.8 3.8 4.9 6.7 4.8 4.2 10.8 4.4 2.5 4.4 2.9 4.4 2.9 14.9 13.2 9.7 6.6 5.9 5.0 0.5 2.6 0.2 3.3 2.6 5.7 8.5 6.4 5.0 4.3 7.2 8.7 8.4 0.2 4.0 1.8 3.1 10.8 4.2 3.6 5.3 4.0 4.8 3.5 4.3 4.0 4.4 4.5 3.7 4.3 6.8 3.4 3.2 2.7 5.5 9.3 2.4 8.8 3.4 7.4 2.1 5.9 4.1 2.7 7.2 5.5 9.2 2.1 6.3 4.0 1.9 9.8 4.1 9.2 3.3 4.0 3.9 4.2 3.4 7.1 5.2 3.9 3.5 7.1 3.6 1.3 3.6 1.8 10.8 4.9 0.0 5.5 2.7 4.1 6.3 2.6 7.3 4.7 4.3 1.8 1.0 2.1 2.5 1.0 3.5 17.4 2.6 2.6 1.9 2.8 4.7 2.1 12.9 2.4 1.6 0.0 7.4 2.8 4.4 8.8 6.9 4.3 1.8 5.8 4.3 3.7 4.3 C12orf75 "AGD3, OCC-1, OCC1" ENSG00000235162 "Chromosome 12 open reading frame 75" Q8TAD7 12 105235290-105396097 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 109.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 841.2;Ductal cells: 626.3;Endometrial ciliated cells: 579.1;Extravillous trophoblasts: 1228.2;Proximal tubular cells: 762.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 661.2" "Group enriched" "Detected in all" 6 "dendritic cells: 661.2;T-cells: 169.9" "Cell line enhanced" "Detected in all" "BJ: 877.8;BJ hTERT+: 517.0;fHDF/TERT166: 432.7;RPTEC TERT1: 425.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065311 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA065311: AB_2685463" "unprognostic (5.96e-2)" "unprognostic (3.85e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (6.73e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (8.61e-2)" "unprognostic (1.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.33e-1)" "unprognostic (7.00e-2)" "prognostic favorable (1.69e-5)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.00e-1)" "unprognostic (4.47e-3)" 12.2 7.3 4.3 8.9 4.7 11.3 11.6 9.4 7.2 31.3 2.1 24.9 9.2 18.5 6.1 8.7 20.9 38.2 2.5 4.1 8.8 58.5 2.0 7.5 14.7 5.3 5.5 6.6 33.8 20.1 3.5 9.3 4.9 41.2 22.0 2.8 4.2 109.3 32.0 9.5 8.8 6.7 6.5 6.3 49.9 26.6 8.8 10.8 2.9 11.8 19.1 5.0 27.0 5.4 43.6 66.6 16.5 14.9 61.2 117.3 30.3 877.8 517.0 194.2 109.4 133.2 3.6 12.2 348.9 432.7 31.7 70.4 36.6 50.3 212.9 241.1 65.0 38.8 17.7 26.5 7.7 29.8 37.7 49.6 12.0 66.4 73.8 113.0 26.1 69.9 1.9 58.8 192.4 14.4 115.3 262.5 39.6 15.8 153.3 21.6 44.3 11.2 425.3 4.3 73.5 18.4 36.9 7.7 16.2 45.2 22.6 7.1 44.2 201.7 77.2 77.0 118.1 34.9 57.6 58.8 44.5 9.7 55.3 39.0 0.7 1.2 165.5 0.5 80.4 19.7 69.2 169.9 23.3 16.2 19.8 102.4 3.5 69.4 1.6 661.2 144.1 88.3 4.3 4.7 9.4 7.2 4.1 8.8 5.3 5.5 4.9 6.5 8.8 5.4 12.8 3.2 2.8 1.6 61.2 100.2 65.9 21.9 38.7 4.5 32.2 26.9 1.1 271.7 20.9 187.6 4.2 35.3 519.5 469.8 841.2 626.3 152.3 579.1 32.6 14.8 333.2 15.8 2.7 222.3 1228.2 53.0 160.5 293.1 2.5 9.7 13.2 1.8 31.9 63.9 2.9 63.6 85.5 5.3 97.3 324.1 15.5 48.2 60.5 40.3 29.1 6.4 299.7 0.5 0.4 420.0 175.5 4.9 160.3 87.0 102.1 762.3 129.7 4.9 6.6 8.6 127.8 102.9 118.6 37.1 61.2 40.6 143.0 0.7 63.9 37.3 C14orf180 "C14orf77, NRAC" ENSG00000184601 "Chromosome 14 open reading frame 180" Q8N912 14 104579764-104590515 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.8;breast: 26.7;heart muscle: 109.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.7;Cardiomyocytes: 7.6;Fibroblasts: 2.0;Hepatic stellate cells: 3.3;Horizontal cells: 3.3;Smooth muscle cells: 1.4" "Cancer enhanced" "Detected in single" "renal cancer: 0.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "ASC diff: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.48e-2)" "unprognostic (1.55e-1)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" "unprognostic (3.19e-3)" "unprognostic (1.89e-1)" "unprognostic (3.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.32e-1)" "unprognostic (9.80e-2)" 40.8 3.1 0.0 0.1 0.2 0.0 26.7 0.2 0.2 0.9 13.5 0.9 0.3 1.1 0.0 0.0 1.8 0.2 109.5 1.5 0.0 1.8 4.1 0.4 0.0 0.5 0.8 0.8 0.8 0.0 1.8 0.8 0.5 0.6 0.0 0.1 0.9 0.4 5.7 0.6 1.4 0.0 0.0 0.5 2.2 0.1 0.4 0.0 0.9 0.7 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 1.5 0.0 0.5 0.8 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.4 7.6 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 C1orf112 FLJ10706 ENSG00000000460 "Chromosome 1 open reading frame 112" Q9NSG2 1 169662007-169854080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 13.5" "Cell type enhanced" "Detected in many" "Microglial cells: 30.0;Spermatocytes: 37.1;Spermatogonia: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023778, HPA024451" Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA023778: AB_1848665, HPA024451: AB_1848667" "unprognostic (4.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (9.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.40e-2)" "unprognostic (2.50e-3)" "unprognostic (2.09e-1)" "unprognostic (9.11e-3)" "unprognostic (8.79e-2)" "unprognostic (3.47e-3)" "unprognostic (5.97e-2)" "unprognostic (1.65e-8)" "unprognostic (1.76e-1)" "unprognostic (2.81e-2)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" 1.8 1.2 0.6 3.3 0.9 9.0 2.9 1.7 0.8 2.3 0.5 2.6 1.2 2.9 1.0 2.0 1.5 1.4 1.0 0.5 0.4 1.1 2.6 1.7 6.3 1.0 0.6 2.2 1.5 13.5 1.0 3.4 0.8 1.8 4.1 5.4 1.5 2.0 0.9 2.4 1.8 2.7 0.7 2.8 1.9 10.3 0.9 11.6 1.7 1.5 7.9 3.1 1.7 1.5 32.7 17.5 21.9 11.3 3.5 4.8 32.2 21.1 10.7 30.0 30.6 19.1 27.7 29.0 9.3 7.0 10.7 26.0 27.6 14.7 34.3 16.9 16.5 27.1 23.0 14.1 1.2 35.8 11.3 1.5 1.9 22.5 5.3 3.5 12.8 16.8 44.9 48.0 24.8 7.9 31.5 10.3 28.8 22.9 12.1 23.3 24.7 19.5 4.0 16.1 16.2 16.9 13.4 22.1 6.9 20.6 21.0 18.3 9.5 24.1 19.1 17.8 28.9 12.9 20.9 30.6 9.0 26.4 24.1 2.2 0.8 1.0 0.6 1.9 0.4 1.4 0.6 0.6 1.2 1.4 0.3 0.5 0.1 2.1 2.3 0.4 0.7 0.6 0.6 0.9 1.7 0.8 0.5 0.4 1.0 0.6 0.8 0.7 0.9 1.5 1.2 0.0 3.3 4.2 4.0 1.8 2.7 2.6 1.2 4.1 1.7 1.8 0.5 0.0 1.5 0.0 6.2 9.1 1.6 1.9 0.0 2.7 8.7 0.9 2.1 2.2 0.0 3.4 9.9 3.4 9.1 2.5 2.6 1.2 4.5 9.8 2.9 3.8 6.2 1.7 9.6 1.2 6.1 3.5 2.1 4.1 2.1 3.0 3.6 30.0 1.3 2.4 0.0 13.0 13.2 3.0 0.3 3.8 5.5 1.0 0.8 0.7 2.0 6.6 6.6 1.4 2.6 37.1 20.3 2.8 1.0 3.8 3.3 2.2 2.6 2.4 C1orf115 "FLJ14146, RDD1" ENSG00000162817 "Chromosome 1 open reading frame 115" Q9H7X2 1 220690363-220699153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 120.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 109.8;Hepatocytes: 121.3;Proximal enterocytes: 255.7;Syncytiotrophoblasts: 183.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 62.4;HUVEC TERT2: 49.7;TIME: 93.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (5.16e-2)" "prognostic favorable (6.52e-4)" "unprognostic (1.31e-1)" "unprognostic (3.93e-2)" "unprognostic (2.03e-1)" "unprognostic (5.69e-3)" "unprognostic (8.65e-2)" "prognostic favorable (5.12e-5)" "unprognostic (3.11e-1)" "unprognostic (1.33e-1)" "unprognostic (1.74e-2)" "unprognostic (4.24e-1)" "unprognostic (4.54e-2)" "unprognostic (9.21e-3)" "unprognostic (1.07e-1)" 50.0 6.8 32.3 6.8 43.4 0.3 28.4 10.8 45.8 14.8 17.3 30.9 112.4 12.5 21.3 5.7 14.4 10.3 18.9 47.5 11.5 52.8 101.4 23.4 8.5 13.1 10.5 17.9 12.1 20.5 17.5 70.2 13.5 31.1 23.3 8.9 74.1 10.6 14.6 9.1 120.9 11.8 10.0 50.0 22.4 7.2 15.9 3.8 16.5 19.3 9.5 6.9 7.2 25.9 1.6 7.3 0.5 10.1 0.0 0.0 29.0 2.0 8.1 4.2 18.3 7.3 7.6 0.0 3.1 0.6 8.5 0.2 16.9 3.4 3.8 0.0 16.9 0.2 1.5 62.4 9.4 0.0 0.2 1.3 5.7 0.3 2.1 0.0 49.7 0.0 4.7 0.0 0.3 6.7 0.0 0.5 12.3 20.4 5.2 0.0 0.1 0.6 9.0 9.8 5.3 7.4 0.0 12.3 30.9 17.5 20.0 0.4 93.6 0.0 0.1 0.3 1.7 1.1 0.0 0.0 0.2 0.0 1.5 0.0 0.2 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.3 43.4 10.8 45.8 47.5 11.5 13.1 10.5 13.5 10.0 15.9 25.9 76.7 3.2 6.7 1.6 5.8 3.4 4.2 1.4 1.8 17.3 29.8 20.4 19.5 17.2 5.1 31.3 6.2 74.4 0.9 109.8 39.2 9.7 1.5 7.6 1.3 51.5 8.4 8.0 20.7 16.6 68.2 5.6 2.0 11.7 0.0 59.0 18.9 121.3 6.4 0.0 2.0 25.6 6.1 4.7 2.7 2.8 3.1 1.4 8.8 5.6 4.8 10.4 0.0 0.0 1.4 13.9 55.5 19.2 0.0 11.0 255.7 58.2 1.9 3.9 0.0 2.1 4.6 0.5 5.5 0.8 1.7 183.9 1.2 54.9 25.1 2.6 C1orf122 FLJ45459 ENSG00000197982 "Chromosome 1 open reading frame 122" Q6ZSJ8 1 37806979-37809454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (7.83e-2)" "unprognostic (4.07e-3)" "unprognostic (1.46e-1)" "unprognostic (7.79e-3)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-3)" "unprognostic (7.12e-2)" "unprognostic (1.69e-1)" "unprognostic (4.44e-2)" "unprognostic (2.81e-3)" "unprognostic (3.89e-1)" "unprognostic (3.58e-2)" "unprognostic (9.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.81e-4)" 48.1 85.5 80.5 10.3 87.3 7.6 44.2 86.7 92.3 39.0 77.0 54.3 11.3 40.4 20.2 50.9 36.4 7.5 76.2 74.7 76.4 74.3 82.5 34.8 7.0 90.8 85.3 31.8 63.0 19.7 101.8 10.3 82.7 60.1 8.2 24.9 40.5 18.1 61.1 37.2 33.0 11.2 87.4 32.4 55.5 39.7 87.7 6.7 42.9 21.6 7.1 45.3 37.3 94.9 38.2 19.7 21.3 25.6 35.3 40.3 84.8 43.5 23.5 29.6 25.8 33.7 37.0 20.7 91.5 27.5 22.1 33.9 14.4 30.1 16.8 39.0 48.1 13.9 23.8 20.8 49.9 18.5 24.7 48.9 65.3 23.8 27.5 33.0 20.5 17.6 35.1 21.1 27.4 36.2 19.4 32.4 57.6 30.7 50.0 29.2 20.9 43.5 30.9 19.4 39.3 63.8 31.5 30.8 38.8 37.6 40.3 11.8 24.9 37.1 33.4 20.9 40.8 49.4 26.7 24.8 33.5 20.5 29.2 1.4 4.9 5.8 3.7 5.8 1.7 1.2 2.5 2.2 3.6 2.9 1.5 2.4 3.0 3.1 5.6 2.5 2.7 2.9 80.5 87.3 86.7 92.3 74.7 76.4 90.8 85.3 82.7 87.4 87.7 94.9 57.4 3.2 14.0 37.9 38.5 55.4 95.5 45.9 51.2 146.1 101.4 95.4 83.3 60.1 30.8 82.8 41.7 84.5 47.9 105.4 266.1 59.6 11.5 62.5 60.5 57.5 113.6 10.8 19.0 109.9 132.4 80.4 31.1 124.8 34.3 67.9 61.8 127.3 146.3 69.0 23.2 73.7 95.6 52.0 56.5 30.2 49.0 80.1 83.6 9.4 94.3 246.5 41.2 15.1 108.2 71.1 88.0 73.7 51.6 201.6 64.6 274.4 25.2 145.0 32.9 55.2 99.8 24.2 19.6 50.2 60.1 106.7 39.2 126.0 57.8 147.8 C1orf158 MGC35194 ENSG00000157330 "Chromosome 1 open reading frame 158" Q8N1D5 1 12746200-12763699 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 18.1;fallopian tube: 26.7;testis: 48.9" "Cell type enhanced" "Detected in some" "Early spermatids: 223.3;Endometrial ciliated cells: 50.3;Late spermatids: 92.8;Respiratory ciliated cells: 88.1;Spermatocytes: 70.7" "Group enriched" "Detected in some" 6 "endometrial cancer: 1.6;glioma: 1.0;ovarian cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028396 Uncertain Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA028396: AB_10603451" "unprognostic (1.11e-2)" "unprognostic (4.94e-3)" "unprognostic (4.62e-1)" "unprognostic (8.00e-2)" "unprognostic (4.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.45e-1)" "unprognostic (3.51e-1)" "unprognostic (1.35e-1)" "unprognostic (2.68e-2)" 0.0 0.0 0.9 0.0 1.1 0.3 0.0 1.0 0.4 1.1 18.1 0.0 0.0 0.4 0.1 0.1 26.7 0.0 0.0 0.9 1.0 0.0 0.0 1.9 0.1 4.3 5.9 0.1 0.1 0.0 0.6 0.1 3.4 0.0 0.0 0.1 0.1 0.0 1.2 0.4 0.0 0.0 3.3 0.1 0.1 48.9 1.9 0.0 0.6 0.0 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.9 1.1 1.0 0.4 0.9 1.0 4.3 5.9 3.4 3.3 1.9 3.6 0.0 3.2 0.5 0.3 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 0.3 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 223.3 50.3 0.4 0.2 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.0 92.8 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 88.1 0.0 6.6 0.1 1.3 70.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 C1orf162 MGC24133 ENSG00000143110 "Chromosome 1 open reading frame 162" Q8NEQ5 1 111473792-111478512 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0;lymphoid tissue: 134.5" "Cell type enhanced" "Detected in many" "granulocytes: 182.3;Hofbauer cells: 195.3;Kupffer cells: 797.4;Langerhans cells: 226.7;Macrophages: 413.5;monocytes: 278.6;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 8 "HDLM-2: 141.3;HL-60: 70.4;NB-4: 40.3;THP-1: 55.2;U-937: 117.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026988 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA026988: AB_10600887" "unprognostic (8.79e-2)" "unprognostic (5.18e-3)" "unprognostic (1.14e-2)" "unprognostic (2.11e-1)" "unprognostic (5.20e-2)" "unprognostic (5.96e-2)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.14e-6)" "unprognostic (1.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" 45.4 23.6 16.3 70.8 16.2 115.0 22.3 17.2 29.0 13.2 19.6 15.8 7.3 11.5 6.3 9.8 22.5 31.2 18.1 16.3 18.4 12.5 41.9 85.7 70.4 20.6 17.3 9.4 9.4 4.8 9.1 15.2 19.7 11.7 17.9 9.5 11.2 6.6 10.1 7.8 21.2 37.6 16.7 134.5 12.5 7.6 23.3 27.7 10.0 7.4 55.9 25.1 10.8 21.4 0.3 0.1 0.5 1.1 0.4 0.6 0.6 0.9 0.1 0.3 0.3 0.2 0.4 0.5 0.5 0.2 0.1 0.2 0.8 0.5 0.6 141.3 0.4 0.4 0.5 0.0 0.4 70.4 11.1 0.0 2.6 0.8 0.9 1.0 2.0 0.7 0.5 0.4 0.5 0.5 0.6 40.3 0.2 0.7 0.8 0.1 0.7 0.1 0.3 0.1 0.5 0.2 0.5 0.6 0.8 0.6 0.3 55.2 0.0 0.8 1.0 0.7 0.6 0.6 0.1 0.6 0.3 117.9 1.2 1114.1 1026.8 1294.8 166.6 1529.2 47.6 231.0 206.5 97.3 1021.6 296.4 318.0 193.6 143.3 536.7 1173.4 302.8 66.7 1189.5 16.3 16.2 17.2 29.0 16.3 18.4 20.6 17.3 19.7 16.7 23.3 21.4 4.4 22.4 43.9 8.1 84.1 7.9 0.7 0.4 0.6 4.0 2.2 5.2 3.8 10.0 4.5 7.3 2.1 1.0 103.4 0.6 0.0 0.2 36.7 0.8 0.9 8.1 1.8 23.5 9.2 0.2 2.0 3.2 0.5 1.0 182.3 0.9 15.7 8.9 195.3 0.0 13.0 0.0 0.0 797.4 226.7 90.7 2.8 413.5 12.4 12.2 278.6 0.2 355.3 6.0 7.7 0.2 0.0 0.7 4.2 0.8 0.9 1.0 0.9 4.2 32.9 2.4 2.9 2.4 2.0 0.2 6.5 1.6 59.8 0.3 0.7 0.3 C1orf68 "LEP7, XP32" ENSG00000198854 "Chromosome 1 open reading frame 68" Q5T750 1 152719522-152720470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 678.3" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 78.3" "Group enriched" "Detected in some" 13 "head and neck cancer: 2.4;melanoma: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HaCaT: 1.8" "Not detected" "Not detected" HPA057942 Approved "Plasma membrane,Cytosol" NA NA 220000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" Cytosol "HPA057942: " "unprognostic (1.73e-1)" "unprognostic (7.46e-2)" "unprognostic (9.34e-2)" 0.4 0.0 0.0 0.0 0.0 0.2 42.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 678.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.8 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 78.3 0.0 0.1 0.0 0.0 0.0 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 23.7;Leydig cells: 23.3;Peritubular cells: 29.7;Skeletal myocytes: 16.9;Smooth muscle cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "RH-30: 34.4;U-138 MG: 15.1;U-2 OS: 8.3;WM-115: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" 2.8 0.6 0.9 0.7 0.9 0.1 1.9 1.2 1.3 4.7 0.1 2.5 1.2 3.3 1.1 1.4 2.3 1.8 3.9 0.9 0.8 0.6 0.4 2.4 0.3 0.3 1.3 1.3 0.3 0.2 0.5 0.8 0.2 1.9 1.1 0.2 1.3 1.0 1.9 1.4 2.3 1.8 0.2 0.6 2.0 1.8 2.5 0.1 2.1 2.1 0.3 2.1 2.6 0.8 0.3 0.0 0.5 0.1 0.0 0.0 0.0 3.9 5.3 0.9 3.3 0.1 0.9 0.0 0.1 1.4 0.6 0.2 0.1 0.4 0.2 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 34.4 0.0 0.0 0.2 0.0 0.8 1.0 0.1 0.2 0.1 0.4 0.1 0.2 15.1 8.3 1.5 4.4 0.1 0.0 0.0 0.5 0.0 6.8 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.9 0.9 1.2 1.3 0.9 0.8 0.3 1.3 0.2 0.2 2.5 0.8 2.0 0.0 0.0 0.0 0.0 6.5 0.2 0.2 0.6 0.8 0.3 0.4 1.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.1 0.0 0.1 1.0 4.2 0.0 0.0 0.6 0.2 0.3 23.7 0.5 0.2 0.0 0.2 1.1 0.0 1.1 0.0 6.2 0.1 0.0 0.0 6.2 0.4 23.3 0.5 5.4 1.0 0.6 0.1 0.0 1.0 0.3 0.1 0.1 29.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 16.9 22.8 0.1 0.5 0.6 3.8 0.8 0.3 2.1 0.1 0.3 C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 2915.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 687.0;Hepatocytes: 2795.1;Leydig cells: 1193.2;Peritubular cells: 640.1" "Cancer enhanced" "Detected in all" "liver cancer: 276.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "ASC diff: 769.5;ASC TERT1: 1012.7;BJ hTERT+: 336.1;HSkMC: 540.2" "Not detected" "Not detected" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 93000000000 14000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" 416.4 136.1 26.4 207.7 28.5 1.7 252.5 27.1 43.1 309.2 36.7 192.4 84.6 209.0 147.2 152.9 315.4 543.8 191.5 25.4 34.8 60.2 2915.2 224.9 209.2 44.3 31.7 485.9 62.1 21.8 33.1 52.9 31.2 174.4 215.2 9.7 96.9 139.1 57.0 104.1 154.2 251.8 30.9 168.5 150.1 90.0 30.9 88.1 139.0 154.7 192.5 455.7 189.8 31.3 0.2 18.6 1.2 10.2 769.5 1012.7 4.5 143.3 336.1 74.7 135.7 0.9 2.0 0.5 19.7 179.6 20.2 1.1 0.3 2.1 6.7 0.7 0.7 0.5 5.6 48.2 230.3 1.8 0.9 540.2 2.8 60.2 4.4 94.2 0.1 0.2 0.4 0.1 9.9 0.0 0.4 1.6 10.3 0.0 0.6 0.2 1.1 1.5 3.1 2.5 0.8 0.9 86.6 1.8 2.1 17.4 0.1 0.0 0.5 34.2 2.6 133.8 0.2 0.6 0.5 0.8 73.6 1.2 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 26.4 28.5 27.1 43.1 25.4 34.8 44.3 31.7 31.2 30.9 30.9 31.3 37.6 16.0 41.0 9.4 5.7 76.2 18.9 22.2 23.9 0.9 4.5 15.4 21.5 171.6 15.5 3.7 0.0 3.7 0.7 0.1 1.9 285.2 6.6 8.7 272.4 30.6 0.0 112.2 2.9 42.9 2.5 687.0 11.2 7.3 5.1 25.7 93.5 2795.1 8.1 5.0 1.7 0.0 2.0 62.8 103.7 29.9 1193.2 6.4 88.9 19.7 1.0 15.2 0.0 1.5 0.6 31.7 0.1 640.1 1.8 9.7 0.0 7.1 4.6 1.1 138.1 34.9 127.6 6.3 5.3 6.3 53.8 2.6 12.8 30.7 0.2 5.2 C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945672 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 477.9" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 142.4;Hepatocytes: 380.3;Hofbauer cells: 282.7;Kupffer cells: 99.3" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "intermediate monocyte: 21.1;non-classical monocyte: 25.9" "Lineage enriched" "Detected in single" 35 "monocytes: 25.9" "Cell line enriched" "Detected in some" 5 "Karpas-707: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB016775 Supported "Secreted to blood" NA NA 34000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" 42.6 12.1 0.8 27.6 1.0 3.2 11.7 0.9 1.4 8.1 1.7 14.3 16.7 7.0 1.3 7.6 12.0 23.0 8.5 0.7 1.1 23.2 477.9 80.0 27.8 3.0 2.6 5.3 1.9 0.9 3.8 48.4 3.0 5.4 13.0 0.4 9.1 0.9 2.1 5.8 30.2 23.6 2.1 46.3 12.0 4.1 3.7 5.5 3.3 2.7 12.5 23.6 5.3 2.1 0.3 0.1 0.1 0.6 0.1 0.0 6.8 0.5 0.3 0.4 0.3 0.4 0.3 0.6 3.5 1.0 0.6 0.5 0.1 0.0 0.3 0.2 0.4 0.3 0.4 52.8 1.1 0.1 0.7 2.7 0.3 0.6 0.1 0.6 0.0 0.7 0.5 284.0 0.0 0.0 0.4 0.5 0.3 0.1 0.0 0.2 16.5 3.0 0.0 0.1 0.3 0.3 2.6 0.3 0.2 0.3 0.2 9.5 0.2 0.2 0.7 0.5 0.1 0.9 31.6 2.7 0.8 0.9 0.1 0.1 5.6 0.0 0.1 21.1 0.1 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.5 0.1 25.9 0.0 0.0 2.2 0.8 1.0 0.9 1.4 0.7 1.1 3.0 2.6 3.0 2.1 3.7 2.1 2.1 25.6 142.4 2.6 1.9 3.3 1.1 2.0 0.6 1.4 1.3 1.3 0.6 25.8 11.2 1.8 0.0 2.1 0.1 1.8 0.0 0.6 0.3 1.5 18.7 1.9 2.4 10.7 6.6 2.7 2.7 19.8 3.1 1.3 3.8 0.2 21.0 380.3 282.7 1.7 6.3 11.3 0.0 99.3 5.0 1.3 6.8 32.6 3.6 7.5 7.3 0.1 0.0 1.0 1.7 4.5 33.1 1.2 0.4 4.0 55.2 35.7 9.4 0.9 0.0 5.6 3.5 0.8 1.4 0.7 2.8 4.0 2.0 0.5 15.8 4.5 C2CD2 "C21orf25, C21orf258, DKFZP586F0422, TMEM24L" ENSG00000157617 "C2 calcium dependent domain containing 2" Q9Y426 21 41885112-41954018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 126.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 51.6;Cone photoreceptor cells: 83.4;Granulosa cells: 100.0;Theca cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 79.1;SK-BR-3: 44.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030922, HPA030924" Enhanced Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA030922: AB_2673660, HPA030924: AB_10669873" "unprognostic (3.02e-3)" "unprognostic (3.69e-2)" "unprognostic (2.21e-2)" "unprognostic (9.63e-2)" "unprognostic (3.15e-3)" "unprognostic (2.93e-2)" "unprognostic (2.39e-2)" "unprognostic (3.44e-2)" "unprognostic (3.00e-2)" "unprognostic (4.39e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.68e-5)" "unprognostic (1.99e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-2)" "unprognostic (1.48e-1)" 39.9 126.3 18.6 8.3 18.0 1.3 23.3 18.4 19.8 12.0 16.9 12.9 4.9 8.3 8.4 10.7 9.4 8.3 7.5 16.4 18.6 10.1 8.6 7.9 9.7 21.8 20.9 18.9 11.3 29.2 7.2 5.2 20.2 17.3 5.8 24.6 10.8 11.5 2.8 15.6 9.0 7.8 20.5 41.4 11.7 3.3 23.4 6.7 8.5 4.1 7.9 12.8 11.4 26.1 13.4 5.5 3.9 8.9 79.1 21.7 15.1 9.3 14.4 5.7 5.2 8.7 15.0 0.2 5.0 18.0 14.0 1.5 13.9 9.7 7.2 0.9 6.2 2.3 7.1 7.1 10.6 1.0 0.0 14.0 8.9 30.3 11.7 12.5 27.1 0.7 8.4 0.1 15.3 1.2 1.9 2.7 21.4 5.7 18.7 1.4 5.7 8.0 8.5 27.8 6.3 2.8 10.1 44.6 8.1 7.6 11.7 5.9 9.3 13.5 1.9 4.5 7.6 5.0 7.9 1.1 39.2 7.7 2.8 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.2 0.1 0.3 0.1 0.5 0.3 0.1 0.3 0.1 0.0 0.3 0.1 18.6 18.0 18.4 19.8 16.4 18.6 21.8 20.9 20.2 20.5 23.4 26.1 24.8 3.2 15.5 20.5 4.4 4.1 9.1 7.6 15.9 51.6 8.2 7.0 3.1 8.6 8.3 3.7 83.4 12.8 4.4 3.4 0.0 5.6 0.3 6.0 6.7 19.3 4.9 5.9 20.3 8.5 4.8 11.9 17.9 8.3 0.0 100.0 46.1 5.2 3.6 1.7 14.4 6.9 6.1 7.0 10.5 0.2 3.7 5.6 1.8 24.4 2.5 3.6 3.1 11.6 18.8 8.1 5.0 2.2 8.1 15.9 3.0 2.5 7.7 36.9 13.1 7.4 17.9 0.1 3.0 14.3 2.6 9.3 2.8 82.4 6.9 16.6 C2CD2L "KIAA0285, TMEM24" ENSG00000172375 "C2CD2 like" O14523 11 119102198-119118544 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Distal enterocytes: 40.6;Proximal enterocytes: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 50.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011044, HPA075369" Approved Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA011044: AB_2668414, HPA075369: " "unprognostic (3.43e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-3)" "prognostic favorable (4.92e-4)" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-3)" "unprognostic (3.37e-3)" "unprognostic (5.28e-2)" "unprognostic (2.09e-1)" "unprognostic (3.99e-3)" "unprognostic (8.19e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (8.02e-2)" "unprognostic (8.32e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" 6.6 8.2 26.9 6.5 27.6 13.6 5.8 15.5 28.9 6.4 15.3 11.1 16.1 6.2 4.8 10.8 8.8 5.3 10.2 26.8 19.6 11.6 13.1 10.3 8.1 18.0 18.4 6.0 11.0 5.7 23.9 3.9 18.4 7.1 7.3 14.1 9.6 5.3 15.3 15.3 17.1 5.1 15.2 14.9 8.1 4.3 21.4 8.5 6.7 7.3 5.7 7.0 6.6 23.7 6.1 4.5 6.0 12.5 7.7 3.2 3.9 9.0 7.8 8.7 7.2 7.3 6.3 9.1 23.1 6.3 9.1 13.4 7.6 3.9 3.4 14.3 6.2 35.7 5.9 5.3 10.2 10.5 50.5 3.7 7.9 16.4 6.1 9.8 5.4 13.5 15.1 16.1 8.3 16.2 11.9 24.9 2.2 15.0 11.8 7.4 5.3 10.5 8.7 3.8 18.7 10.5 3.8 20.1 5.9 2.3 35.3 13.9 6.7 8.1 2.8 9.9 16.1 6.8 4.5 3.5 4.9 17.6 9.1 0.5 1.3 2.7 0.2 1.4 0.4 0.1 0.6 0.6 0.5 0.0 0.6 0.3 0.4 0.8 2.0 0.3 0.6 0.5 26.9 27.6 15.5 28.9 26.8 19.6 18.0 18.4 18.4 15.2 21.4 23.7 5.1 6.4 4.2 9.4 3.7 10.7 1.6 2.3 10.2 15.6 6.8 5.0 2.4 2.8 4.3 1.8 37.5 0.9 7.4 40.6 3.9 3.4 5.4 12.1 2.6 5.7 1.2 7.0 15.1 2.8 1.7 2.5 3.6 4.6 2.5 2.2 11.4 5.4 9.4 21.9 15.0 8.0 0.0 13.9 16.1 1.3 2.1 11.4 7.2 5.6 15.3 5.9 7.2 4.5 8.4 5.1 10.4 1.5 7.2 3.2 33.0 4.0 21.9 29.9 6.6 2.1 3.6 3.7 2.0 10.3 10.9 1.1 8.6 3.6 5.5 1.9 C2orf72 LOC257407 ENSG00000204128 "Chromosome 2 open reading frame 72" A6NCS6 2 231037523-231049719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.6;liver: 18.7" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Cholangiocytes: 47.1;Hepatocytes: 129.1;Oligodendrocyte precursor cells: 45.8;Paneth cells: 51.3" "Cancer enhanced" "Detected in many" "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.9;CACO-2: 2.2;EFO-21: 3.3;OE19: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044962 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "HPA044962: AB_10960863" "unprognostic (4.90e-2)" "unprognostic (7.03e-2)" "unprognostic (2.15e-1)" "unprognostic (7.44e-3)" "unprognostic (2.88e-2)" "unprognostic (6.41e-2)" "unprognostic (3.38e-1)" "unprognostic (6.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.84e-1)" "prognostic favorable (5.27e-4)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (2.78e-1)" "unprognostic (7.23e-3)" "unprognostic (2.70e-2)" "unprognostic (5.19e-2)" 0.0 0.0 6.7 0.0 8.2 0.0 0.3 4.3 8.8 0.0 0.0 3.0 0.6 0.0 0.1 0.0 0.0 0.4 0.0 8.7 6.2 0.2 18.7 0.1 0.0 8.4 12.1 0.0 1.4 0.2 1.1 0.9 6.0 0.5 0.7 0.0 0.1 0.0 0.0 0.1 1.1 0.0 5.8 0.0 1.5 0.1 14.6 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.5 0.4 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 4.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 1.0 0.5 0.5 0.6 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 8.2 4.3 8.8 8.7 6.2 8.4 12.1 6.0 5.8 14.6 6.1 0.0 0.0 0.0 163.2 0.5 0.1 0.1 0.0 0.0 1.9 5.9 6.0 0.5 47.1 0.0 0.0 0.0 1.8 0.2 32.8 1.9 3.9 13.6 0.1 0.2 0.2 4.9 10.7 33.4 2.0 11.9 0.2 4.6 0.1 0.0 0.1 3.6 129.1 0.6 0.0 15.0 14.8 0.0 2.9 0.0 30.8 0.3 0.2 1.8 6.5 0.0 15.7 0.0 45.8 20.1 0.8 51.3 4.1 0.2 0.7 10.7 1.8 0.0 0.3 0.0 0.0 0.1 0.5 0.9 0.0 0.0 5.2 0.3 0.0 28.8 0.3 C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "granulocytes: 36.8;Hofbauer cells: 161.5;Kupffer cells: 139.7;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 898.6;eosinophil: 450.8;intermediate monocyte: 273.6;non-classical monocyte: 371.3" "Group enriched" "Detected in many" 20 "granulocytes: 898.6;monocytes: 371.3" "Cell line enriched" "Detected in some" 9 "HMC-1: 148.0" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" 18.0 10.6 3.8 40.1 4.0 22.9 6.7 4.7 5.7 6.8 4.4 7.4 6.6 3.8 1.5 3.9 5.9 16.2 4.4 3.9 6.9 3.1 10.8 18.6 12.4 10.1 6.3 3.7 6.0 3.3 2.5 22.0 9.0 3.3 6.8 0.8 5.6 4.3 1.4 2.0 9.7 15.6 8.3 21.4 5.3 2.1 7.8 4.9 2.4 2.6 5.1 15.2 2.7 15.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.9 0.5 3.8 0.0 0.0 1.6 0.0 0.0 2.2 0.1 0.0 0.0 0.1 0.0 0.0 12.0 0.0 0.0 1.4 15.6 148.0 0.7 0.0 0.2 0.4 0.3 0.7 1.2 4.0 8.2 0.7 0.0 0.7 5.2 0.1 0.0 0.0 0.1 3.1 15.1 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 6.6 0.6 0.5 0.4 0.1 0.3 0.3 0.0 0.4 8.5 6.4 0.4 898.6 105.0 450.8 21.8 273.6 26.9 0.2 10.6 14.5 31.1 0.3 2.0 7.8 14.0 4.1 371.3 2.8 11.0 76.0 3.8 4.0 4.7 5.7 3.9 6.9 10.1 6.3 9.0 8.3 7.8 15.6 0.7 0.0 3.0 0.3 1.1 0.5 0.1 0.1 0.0 0.1 0.3 0.9 0.6 1.5 2.5 0.0 2.1 0.7 5.9 0.0 0.0 0.0 3.0 0.0 0.1 6.6 0.0 0.8 0.4 0.2 1.0 0.6 0.0 0.0 36.8 0.0 1.8 0.8 161.5 0.0 0.3 0.0 0.0 139.7 19.8 4.2 1.2 105.7 0.0 8.4 16.2 0.0 8.2 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.7 0.4 19.7 0.7 1.0 0.0 0.2 0.0 0.6 1.5 8.6 0.1 0.0 0.0 C4orf19 FLJ11017 ENSG00000154274 "Chromosome 4 open reading frame 19" Q8IY42 4 37453925-37623495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.0" "Cell type enhanced" "Detected in many" "Astrocytes: 45.4;Distal enterocytes: 61.3;Exocrine glandular cells: 51.8;Oligodendrocyte precursor cells: 46.8;Pancreatic endocrine cells: 53.6;Paneth cells: 67.2;Proximal enterocytes: 52.3;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 8.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.6" "Group enriched" "Detected in some" 5 "OE19: 64.6;RT4: 81.0;SK-BR-3: 32.6;T-47d: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043458, HPA052894" Enhanced Supported "Cell Junctions" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA043458: AB_10960696, HPA052894: AB_2681982" "unprognostic (8.83e-2)" "unprognostic (7.86e-2)" "unprognostic (3.00e-3)" "unprognostic (2.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.59e-3)" "unprognostic (5.55e-2)" "unprognostic (2.29e-1)" "unprognostic (6.66e-2)" "unprognostic (9.96e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.49e-11)" "unprognostic (1.33e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-3)" "unprognostic (8.19e-3)" 3.4 0.3 2.7 3.0 2.9 3.8 3.8 5.3 4.3 10.2 5.9 25.5 17.7 6.7 0.2 2.1 2.8 9.2 0.4 3.5 4.2 12.4 36.0 3.7 0.5 4.9 4.9 0.2 24.9 16.0 1.2 7.6 4.2 1.7 23.7 4.6 28.2 6.8 0.2 1.6 19.6 4.0 4.5 0.3 20.7 1.4 4.9 0.2 1.5 0.4 4.3 8.8 2.9 4.1 0.1 0.2 3.2 0.3 0.0 0.0 4.2 0.7 0.0 0.0 0.0 12.6 5.2 0.1 3.0 0.0 0.1 0.4 0.2 0.8 0.1 0.0 0.4 0.0 8.3 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 14.3 0.2 0.2 0.5 64.6 1.7 0.1 7.8 0.2 12.7 81.0 0.9 0.3 0.5 32.6 1.0 4.0 113.1 0.7 0.6 0.4 4.5 0.2 1.6 0.2 0.1 0.5 0.0 6.9 5.6 0.9 1.4 2.1 0.6 0.2 0.4 0.2 0.3 0.4 0.2 0.5 0.5 0.8 8.6 0.8 0.1 1.6 0.7 0.3 2.7 2.9 5.3 4.3 3.5 4.2 4.9 4.9 4.2 4.5 4.9 4.1 0.3 0.0 12.6 45.4 0.7 0.3 7.8 4.9 0.0 0.6 7.1 3.9 0.2 27.1 10.1 11.0 0.0 6.7 0.2 61.3 11.7 25.2 1.2 9.5 0.4 0.9 9.6 0.0 2.3 51.8 4.7 0.3 33.6 5.5 0.0 0.0 0.0 13.1 0.7 0.0 2.4 28.0 4.1 0.0 0.3 2.4 0.0 0.2 3.6 22.5 0.6 5.3 0.0 46.8 1.8 53.6 67.2 0.0 0.0 7.8 52.3 9.2 12.3 1.0 0.0 0.2 0.9 0.3 0.2 0.5 0.0 47.5 0.4 0.1 31.8 19.1 C5orf46 "MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "salivary gland: 181.8;skin 1: 113.1" "Group enriched" "Detected in some" 12 "Early spermatids: 320.9;Late spermatids: 189.9" "Cancer enhanced" "Detected in many" "renal cancer: 8.3" "Region enriched" "Detected in single" 10 "cerebellum: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 54.2;PC-3: 90.8;SiHa: 20.2;U-2 OS: 58.2;U-251 MG: 23.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" NA NA 54000 "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.72e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.26e-4)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.69e-3)" "unprognostic (1.99e-2)" "unprognostic (3.08e-2)" "unprognostic (2.22e-1)" "unprognostic (4.96e-2)" "unprognostic (2.86e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.75e-9)" "unprognostic (6.48e-3)" "unprognostic (3.47e-2)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 13.5 2.3 0.1 1.6 0.7 0.4 0.0 0.1 0.4 0.4 0.0 0.2 9.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.2 0.2 0.9 0.0 0.6 181.8 0.1 0.8 113.1 0.0 3.2 0.0 0.0 0.0 19.2 0.0 0.3 0.2 0.1 0.3 0.0 3.6 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 2.4 1.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.6 0.0 0.2 0.2 0.0 4.6 0.2 0.0 0.0 0.0 0.0 1.1 0.0 8.9 54.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 20.2 0.3 0.3 11.1 0.0 0.0 0.0 10.0 58.2 0.8 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 9.2 3.7 11.0 15.7 0.2 1.8 0.0 0.5 0.2 0.0 0.0 15.9 320.9 0.7 0.4 0.3 0.0 0.0 0.0 3.3 0.6 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 189.9 1.8 0.2 3.6 0.0 0.6 7.7 0.0 0.0 0.0 4.2 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 1.1 0.8 0.0 20.6 1.4 0.1 0.0 0.0 0.2 C6orf132 bA7K24.2 ENSG00000188112 "Chromosome 6 open reading frame 132" Q5T0Z8 6 42101119-42142620 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 157.0;skin 1: 73.6" "Cell type enhanced" "Detected in many" "Late spermatids: 163.8;Pancreatic endocrine cells: 219.9;Prostatic glandular cells: 144.6;Urothelial cells: 226.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 57.8;CACO-2: 52.0;CAPAN-2: 44.0;OE19: 181.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA044588 Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Cytosol" "HPA044588: AB_10794293" "unprognostic (7.09e-2)" "unprognostic (8.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.24e-3)" "unprognostic (1.60e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (6.78e-2)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (4.90e-4)" "unprognostic (1.31e-1)" "unprognostic (4.26e-3)" "unprognostic (1.04e-2)" "unprognostic (5.53e-2)" "unprognostic (2.47e-2)" "unprognostic (1.30e-1)" 3.7 1.0 0.4 2.2 0.4 1.0 8.7 0.6 0.7 31.7 0.3 14.1 33.4 1.0 0.1 157.0 5.8 6.6 1.8 0.4 0.1 14.9 0.5 5.8 0.3 0.4 0.1 0.2 18.0 2.5 1.7 1.5 0.4 12.1 11.7 0.9 47.1 2.3 0.9 73.6 20.7 0.5 0.0 0.1 36.2 0.7 0.3 0.7 10.7 0.3 13.9 9.9 54.9 0.6 57.8 0.5 0.0 0.1 0.3 6.1 29.0 2.9 4.4 7.6 7.6 52.0 44.0 0.0 5.4 5.4 0.1 37.5 0.1 17.3 5.2 5.1 7.2 2.8 5.0 12.1 2.0 0.0 0.2 4.0 30.4 5.9 8.8 3.1 0.0 0.3 1.7 0.5 1.7 20.4 0.4 0.3 3.6 181.7 1.5 0.1 0.0 0.3 6.2 25.5 3.0 0.1 4.7 35.2 0.1 4.1 25.2 0.3 0.8 0.4 3.5 13.5 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.5 0.2 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.5 0.1 0.0 0.3 0.0 0.1 0.4 0.4 0.6 0.7 0.4 0.1 0.4 0.1 0.4 0.0 0.3 0.6 0.8 44.8 16.6 0.3 0.2 52.5 88.6 31.8 19.4 0.8 41.7 19.8 5.1 45.8 63.1 51.5 20.9 12.4 1.2 89.9 0.0 57.9 22.2 91.9 9.4 2.8 7.3 0.0 0.5 134.7 1.0 9.2 57.1 135.8 1.3 18.3 1.4 0.0 0.8 5.0 0.5 41.3 38.7 1.2 6.8 163.8 0.6 1.5 12.4 0.0 3.8 0.5 4.1 0.5 0.2 219.9 66.8 1.5 0.3 144.6 102.7 7.7 92.1 7.9 0.0 7.9 4.9 4.9 9.1 81.4 82.0 4.1 1.5 45.4 43.7 226.0 C6orf15 STG ENSG00000204542 "Chromosome 6 open reading frame 15" Q6UXA7 6 31111223-31112575 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 5.5;lymphoid tissue: 3.5;skin 1: 6.7" "Cell type enriched" "Detected in some" 14 "Breast glandular cells: 73.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "RH-30: 13.4;U-2 OS: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA001436 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 30: Mammary glandular cells - Lactation" "HPA001436: AB_2243752" "unprognostic (2.73e-2)" "unprognostic (5.39e-2)" "unprognostic (1.46e-2)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.35e-1)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.72e-1)" "unprognostic (1.90e-1)" "unprognostic (1.34e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 3.5 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.3 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 2.3 0.0 1.3 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 C8orf74 ENSG00000171060 "Chromosome 8 open reading frame 74" Q6P047 8 10672628-10700590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 171 "testis: 17.0" "Group enriched" "Detected in some" 90 "Early spermatids: 186.5;Late spermatids: 392.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027986 Uncertain Uncertain Nucleoplasm NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA027986: AB_10600762" "unprognostic (4.24e-2)" "unprognostic (5.62e-2)" "unprognostic (4.68e-2)" "unprognostic (5.54e-2)" "unprognostic (2.37e-2)" "unprognostic (1.56e-4)" "unprognostic (6.82e-2)" "unprognostic (2.20e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 186.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 392.8 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C9orf152 bA470J20.2 ENSG00000188959 "Chromosome 9 open reading frame 152" Q5JTZ5 9 110190048-110208159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.6;salivary gland: 25.4;stomach 1: 32.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.4;Intestinal goblet cells: 139.7;Ionocytes: 40.7;Paneth cells: 40.0;Undifferentiated cells: 79.8" "Cancer enhanced" "Detected in many" "prostate cancer: 27.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 149.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA050769 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Nucleoli "HPA050769: AB_2681230" "unprognostic (1.90e-2)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "prognostic favorable (7.22e-5)" "unprognostic (2.28e-1)" "unprognostic (1.79e-3)" "unprognostic (6.86e-2)" "unprognostic (1.34e-1)" "unprognostic (4.84e-2)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (5.09e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (4.57e-1)" "unprognostic (2.49e-1)" "unprognostic (1.06e-2)" 0.1 0.0 0.5 2.1 0.4 0.0 12.4 0.2 0.4 10.4 0.1 32.8 19.0 2.3 0.0 3.0 3.7 5.5 0.0 0.4 0.1 0.2 0.8 5.8 0.0 0.6 0.4 0.0 5.1 0.0 0.1 0.0 0.6 17.0 41.6 0.0 25.4 1.4 0.0 5.4 15.1 1.2 0.2 0.1 32.9 0.0 0.5 0.1 0.1 0.0 0.2 1.2 0.4 0.6 0.0 1.3 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.1 0.0 149.2 0.2 0.0 0.0 0.2 0.0 0.6 0.1 0.1 0.0 9.3 0.0 0.0 18.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.2 0.4 0.4 0.1 0.6 0.4 0.6 0.2 0.5 0.6 0.4 9.6 16.3 0.3 0.2 0.3 3.4 5.9 6.2 0.0 20.5 10.8 0.1 20.0 14.5 0.0 0.0 0.0 0.1 35.4 0.0 6.0 0.0 4.0 2.0 0.5 25.9 0.0 0.1 11.1 0.0 0.2 25.0 13.9 0.0 0.0 0.0 3.3 0.1 0.0 0.1 139.7 40.7 0.0 1.0 0.0 0.0 0.6 10.6 0.0 0.0 0.0 0.0 0.0 0.1 3.9 40.0 0.0 0.0 12.4 4.4 0.0 5.2 0.0 0.0 0.4 0.9 0.0 0.0 10.9 0.4 0.0 0.4 0.0 79.8 5.5 CA12 HsT18816 ENSG00000074410 "Carbonic anhydrase 12" O43570 15 63321378-63381846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 290.2;skin 1: 142.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 174.6;Distal enterocytes: 422.6;Paneth cells: 160.8;Squamous epithelial cells: 185.3;Suprabasal keratinocytes: 252.2;Undifferentiated cells: 138.8" "Cancer enhanced" "Detected in all" "renal cancer: 109.3" "Region enhanced" "Detected in many" "basal ganglia: 42.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 213.0;ASC TERT1: 213.0;RT4: 226.2;SK-BR-3: 177.9;T-47d: 286.8;U-138 MG: 300.5;U-87 MG: 361.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008773, CAB025181, CAB062549, CAB068179, HPA073203" Enhanced NA NA 52000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB025181: , CAB062549: AB_2665617, CAB068179: AB_2665616, HPA008773: AB_1078394, HPA073203: AB_2686580" "unprognostic (2.01e-1)" "unprognostic (8.38e-3)" "unprognostic (3.47e-1)" "unprognostic (3.25e-3)" "unprognostic (2.73e-2)" "unprognostic (2.47e-2)" "unprognostic (7.48e-2)" "unprognostic (3.43e-3)" "unprognostic (2.29e-1)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.80e-6)" "unprognostic (2.59e-1)" "unprognostic (1.51e-1)" "unprognostic (2.38e-1)" "unprognostic (6.56e-2)" "unprognostic (7.26e-2)" "unprognostic (1.21e-1)" 8.3 0.2 6.1 18.7 42.9 0.1 42.8 5.2 7.2 50.7 129.0 104.1 0.4 28.4 4.1 75.4 25.0 7.7 3.2 6.8 6.6 290.2 0.7 3.0 0.3 0.9 9.6 0.6 70.2 0.3 10.7 2.3 3.2 5.5 94.2 1.9 26.3 8.7 0.6 142.1 8.2 56.2 0.9 0.8 7.9 0.6 16.1 0.1 4.6 0.1 8.7 27.4 49.0 1.5 0.0 213.0 3.5 0.5 27.3 213.0 11.2 15.7 13.7 2.5 4.1 1.6 0.5 0.0 51.4 12.6 81.7 1.1 0.0 10.4 6.2 0.3 7.7 0.0 13.9 0.4 0.6 0.0 0.3 81.3 11.4 63.6 20.4 0.1 2.7 0.1 0.0 0.3 2.8 125.2 0.3 0.2 3.4 0.0 33.4 0.1 0.0 0.1 0.2 226.2 1.8 0.2 0.9 177.9 0.0 2.1 286.8 0.1 0.4 300.5 16.0 10.1 0.2 0.0 0.0 0.1 361.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 42.9 5.2 7.2 6.8 6.6 0.9 9.6 3.2 0.9 16.1 1.5 0.7 0.0 6.9 11.4 1.1 174.6 20.0 87.7 93.4 0.1 93.5 50.4 1.3 1.5 30.3 40.5 0.0 0.4 1.6 422.6 54.8 17.2 12.1 28.4 6.2 2.1 8.4 0.0 1.3 58.4 2.0 14.6 8.2 75.0 1.3 0.3 0.0 0.2 0.6 0.0 0.8 111.4 20.3 0.3 11.9 3.9 0.0 4.0 23.2 0.0 0.0 2.7 0.0 1.0 0.1 10.2 160.8 0.0 0.0 19.8 15.6 73.9 6.9 0.2 0.0 0.2 4.1 0.0 0.0 185.3 252.2 1.8 2.8 0.1 138.8 17.4 CA14 ENSG00000118298 "Carbonic anhydrase 14" Q9ULX7 1 150257251-150265078 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 33.3;retina: 39.4;skeletal muscle: 33.7;tongue: 47.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 69.5;Melanocytes: 53.4;Muller glia cells: 164.5;Oligodendrocytes: 25.7" "Cancer enriched" "Detected in many" 5 "melanoma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "AF22: 102.2;AN3-CA: 65.9;NTERA-2: 83.9;SK-MEL-30: 217.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008482 Approved Approved "Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA008482: AB_1078395" "unprognostic (3.06e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (3.25e-2)" "prognostic favorable (8.47e-4)" "unprognostic (7.28e-2)" "unprognostic (4.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.47e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" "unprognostic (5.89e-3)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (5.80e-2)" 0.0 0.2 8.6 0.2 14.4 1.2 0.3 15.9 27.6 0.1 33.3 3.8 0.4 0.1 0.4 1.9 1.7 0.6 7.6 8.7 11.3 0.3 8.7 0.2 0.1 14.3 14.0 1.4 0.2 3.4 0.5 0.3 14.6 4.0 0.7 39.4 0.4 20.3 33.7 5.4 1.3 0.5 12.5 0.2 1.2 0.5 13.3 0.0 1.0 47.4 0.0 0.6 0.1 20.6 0.9 0.2 102.2 65.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.5 0.0 0.1 0.3 0.2 0.1 0.0 0.2 1.1 0.3 0.3 6.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.1 0.6 0.0 0.9 0.3 0.3 83.9 0.4 1.1 0.1 0.3 0.3 0.0 0.2 3.2 1.8 0.0 0.3 217.9 14.6 0.8 0.4 0.1 0.1 0.2 0.2 0.4 0.9 4.9 0.4 0.7 0.5 0.2 0.0 0.2 0.4 0.4 0.5 0.1 0.5 0.2 0.3 0.0 0.6 0.3 0.3 0.5 0.0 0.1 0.6 0.0 0.0 8.6 14.4 15.9 27.6 8.7 11.3 14.3 14.0 14.6 12.5 13.3 20.6 0.1 3.2 0.5 0.3 0.2 2.2 0.3 0.3 0.0 1.3 0.1 0.0 69.5 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.3 0.1 0.6 0.0 0.0 0.1 0.7 0.1 3.4 0.0 0.2 0.0 0.0 0.0 6.1 0.1 0.0 0.1 0.3 0.0 0.3 0.9 0.2 0.9 0.1 53.4 0.0 0.0 164.5 0.0 0.0 25.7 1.9 0.3 3.4 0.0 0.3 0.0 0.1 0.1 4.9 0.0 0.6 0.5 0.0 0.2 0.0 0.4 0.3 0.1 0.0 0.2 0.5 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 687.4;stomach 1: 1108.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1773.2;Erythroid cells: 2448.1;Gastric mucus-secreting cells: 1380.7;Muller glia cells: 1536.4;Paneth cells: 781.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 263.8;HEK 293: 1097.8;THP-1: 461.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 7.4 10.1 95.9 36.8 127.5 246.8 37.9 122.1 143.8 5.0 444.0 687.4 285.2 2.9 10.6 19.8 2.7 112.7 15.9 105.2 107.8 331.2 273.5 43.1 6.6 115.5 112.0 0.4 55.1 10.1 6.1 19.6 114.2 1.9 643.6 390.4 74.7 68.4 42.7 81.0 31.3 32.3 98.2 8.4 1108.7 21.2 115.6 5.1 15.9 62.8 4.3 2.9 5.2 145.5 3.7 2.8 12.2 0.0 0.1 0.0 31.2 0.0 0.0 0.0 0.0 15.1 0.9 0.0 9.5 0.0 0.1 263.8 37.4 13.2 0.0 0.0 1097.8 35.8 17.0 0.5 0.0 23.7 5.1 0.0 63.9 0.0 3.7 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.4 41.4 3.7 86.5 0.0 21.2 1.3 0.5 3.7 8.8 0.2 0.3 5.0 0.0 0.1 9.6 0.0 461.5 0.0 0.0 6.6 0.0 0.4 0.4 1.0 0.1 1.8 0.1 0.0 51.2 5.3 8.6 0.2 15.0 7.4 1.3 0.1 0.8 15.4 3.0 0.0 0.0 12.6 0.1 13.4 1.4 0.0 33.3 95.9 127.5 122.1 143.8 105.2 107.8 115.5 112.0 114.2 98.2 115.6 145.5 19.4 16.0 79.9 34.0 19.6 90.6 1.3 152.5 17.6 23.1 56.9 18.4 19.8 430.4 22.4 161.8 64.6 15.2 2.4 1773.2 348.3 60.1 65.9 3.3 1.3 26.7 30.5 2448.1 1.4 11.3 403.1 6.4 1380.7 8.3 15.9 0.4 4.2 135.6 35.4 13.5 22.3 116.0 10.2 11.0 216.5 232.1 3.4 51.8 74.7 6.5 6.6 1536.4 1.0 3.0 226.4 16.1 781.9 2.2 10.3 3.5 0.3 468.2 3.9 66.1 0.0 12.1 8.2 3.1 2.8 31.2 111.7 17.1 11.7 0.7 390.8 0.5 CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 151.6;placenta: 80.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 146.4;Excitatory neurons: 35.5;Fibroblasts: 39.5;Horizontal cells: 35.3;Inhibitory neurons: 40.5;Muller glia cells: 39.4" "Cancer enriched" "Detected in many" 4 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 65.0;HSkMC: 218.8;hTERT-HME1: 118.5;WM-115: 60.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" NA NA 800000 "Cluster 6: Brain - Smell perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 33: Fibroblasts - ECM organization" "CAB025746: , HPA002981: AB_1078916" "unprognostic (1.74e-2)" "unprognostic (8.26e-2)" "unprognostic (1.34e-2)" "unprognostic (1.33e-2)" "unprognostic (9.32e-2)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.12e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (5.52e-2)" "unprognostic (2.59e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (5.75e-4)" 17.3 7.9 102.0 15.1 139.6 0.1 9.2 151.6 145.4 27.6 1.2 28.2 4.4 3.9 1.3 11.5 9.2 6.2 18.1 143.1 96.2 2.2 0.6 5.0 14.3 87.4 84.1 1.5 2.2 0.2 31.0 80.6 120.7 5.1 14.4 66.8 5.9 4.7 2.3 13.0 15.8 6.1 66.3 13.3 11.1 3.0 99.4 1.2 7.3 6.5 9.8 16.2 31.0 60.8 0.0 0.0 0.6 0.0 4.2 1.2 0.0 0.0 0.0 9.4 1.8 0.0 0.0 0.1 0.5 0.0 0.1 0.1 0.0 0.0 3.8 0.0 0.0 3.7 0.0 0.0 65.0 0.0 0.2 218.8 0.0 0.1 118.5 0.0 5.3 0.0 0.0 0.2 2.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.1 4.1 0.0 0.0 5.0 0.0 0.1 9.1 0.0 32.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 60.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.0 139.6 151.6 145.4 143.1 96.2 87.4 84.1 120.7 66.3 99.4 60.8 4.2 0.0 0.5 11.4 0.0 6.6 0.1 0.0 0.6 146.4 0.1 0.8 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.0 0.0 0.2 8.0 0.0 0.0 35.5 0.0 0.8 39.5 0.5 0.0 0.0 0.0 3.6 0.0 1.2 35.3 40.5 0.0 0.0 0.0 10.7 8.3 0.6 0.3 24.9 1.9 0.0 39.4 0.0 18.6 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.6 0.0 16.3 3.6 3.1 2.6 0.3 4.3 0.7 0.6 0.0 0.0 0.1 CADPS "CAPS, CAPS1, KIAA1121, UNC-31" ENSG00000163618 "Calcium dependent secretion activator" Q9ULU8 3 62398346-62875416 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.6;retina: 184.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 772.6;Cone photoreceptor cells: 627.6;Excitatory neurons: 830.8;Inhibitory neurons: 1152.7;Oligodendrocyte precursor cells: 266.9" "Cancer enhanced" "Detected in many" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 11.5;SCLC-21H: 19.7;SK-MEL-30: 9.0;U-698: 13.2;U-87 MG: 20.5" HPA059328 Enhanced Supported Approved Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA059328: AB_2683982" "unprognostic (3.46e-3)" "unprognostic (1.40e-2)" "unprognostic (1.61e-2)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (3.12e-2)" "unprognostic (9.27e-2)" "unprognostic (5.73e-2)" "unprognostic (2.08e-3)" "unprognostic (3.21e-1)" "unprognostic (4.20e-3)" "unprognostic (1.90e-2)" "unprognostic (2.04e-1)" "unprognostic (7.91e-3)" "unprognostic (5.35e-3)" 0.4 16.4 32.2 2.0 47.7 0.1 0.7 18.7 84.6 2.8 0.0 2.8 3.2 0.6 2.5 0.2 0.4 2.4 16.7 32.1 26.0 0.2 0.2 0.8 0.5 83.2 39.7 1.9 13.5 0.2 39.6 0.2 84.5 3.6 2.4 184.3 1.4 2.8 0.1 1.4 3.3 0.8 4.1 0.6 3.0 3.2 33.0 0.6 0.2 0.0 0.7 0.4 1.4 61.7 0.0 0.0 0.8 0.0 4.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.5 11.5 0.0 0.1 0.0 0.0 0.0 0.0 19.7 1.5 0.0 0.0 9.0 0.4 0.0 0.0 0.1 1.6 0.1 3.3 0.9 0.0 1.7 13.2 20.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 47.7 18.7 84.6 32.1 26.0 83.2 39.7 84.5 4.1 33.0 61.7 0.0 0.0 1.9 93.0 0.1 1.3 0.2 0.0 0.0 772.6 0.5 2.8 25.6 7.2 0.0 0.0 627.6 0.1 0.0 0.4 0.0 4.1 1.1 0.2 1.1 0.9 95.9 0.0 830.8 0.4 0.0 3.2 0.0 0.1 42.5 0.2 0.0 0.0 0.0 47.1 1152.7 5.0 0.0 0.0 1.6 2.1 15.2 0.0 8.8 30.0 0.0 21.3 0.0 266.9 27.0 0.9 1.3 2.6 0.0 0.3 0.7 0.1 0.0 64.7 0.0 3.2 1.2 0.2 0.7 0.0 0.1 0.0 0.4 36.9 1.8 0.2 CALML3 CLP ENSG00000178363 "Calmodulin like 3" P27482 10 5524961-5526771 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 507.1;skin 1: 179.0;vagina: 200.8" "Cell type enriched" "Detected in some" 8 "Squamous epithelial cells: 1257.1" "Cancer enhanced" "Detected in many" "cervical cancer: 150.9;head and neck cancer: 196.3" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 21.5;hTCEpi: 8.6;RPMI-8226: 6.0" "Not detected" "Not detected" "CAB010070, HPA044999" Approved NA NA 1200000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB010070: , HPA044999: AB_2679177" "unprognostic (1.02e-3)" "unprognostic (1.18e-2)" "unprognostic (4.33e-2)" "unprognostic (1.37e-1)" "unprognostic (1.29e-2)" "unprognostic (2.16e-1)" "unprognostic (2.93e-1)" "unprognostic (3.11e-1)" "unprognostic (1.02e-2)" "unprognostic (9.64e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-2)" "unprognostic (1.71e-1)" "unprognostic (2.56e-1)" "unprognostic (1.65e-1)" "unprognostic (4.43e-3)" 0.5 0.1 0.2 0.0 0.2 0.0 5.4 1.5 0.1 107.9 0.0 0.1 0.0 0.1 0.1 507.1 1.2 0.0 0.1 0.0 0.3 17.3 1.6 0.0 0.0 0.5 0.3 0.1 0.2 0.0 0.3 0.0 0.2 2.9 0.0 0.0 121.0 0.1 1.0 179.0 0.2 0.0 0.0 0.1 0.3 1.7 0.7 79.5 0.1 0.0 39.8 0.2 200.8 0.0 21.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.5 0.1 0.0 0.3 0.5 0.3 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 28.4 29.8 6.3 157.1 2.2 13.3 22.4 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 5.9 0.0 4.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 28.5 0.0 1.4 8.3 0.3 0.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 6.5 0.0 59.6 0.7 0.3 0.0 0.0 0.9 6.7 0.1 1257.1 55.0 0.0 0.7 0.0 0.2 30.6 CALML5 CLSP ENSG00000178372 "Calmodulin like 5" Q9NZT1 10 5498697-5499570 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 3060.6" "Group enriched" "Detected in some" 4 "Breast glandular cells: 172.1;Breast myoepithelial cells: 156.1;Suprabasal keratinocytes: 390.7" "Group enriched" "Detected in many" 6 "breast cancer: 97.6;cervical cancer: 189.1;head and neck cancer: 206.0;melanoma: 222.1;urothelial cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "A-431: 400.3" "Not detected" "Not detected" HPA040725 Enhanced Approved "Plasma membrane,Cytosol" NA NA 48000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA040725: AB_10793863" "unprognostic (7.68e-3)" "unprognostic (5.06e-3)" "unprognostic (5.64e-2)" "prognostic favorable (2.59e-5)" "unprognostic (4.82e-2)" "unprognostic (2.67e-1)" "unprognostic (1.37e-1)" "unprognostic (8.27e-2)" "unprognostic (1.14e-1)" "unprognostic (2.79e-1)" "unprognostic (1.71e-1)" "unprognostic (4.99e-2)" 3.9 0.5 0.0 0.0 0.0 0.1 41.2 0.0 0.0 94.0 0.0 0.8 0.0 0.3 0.7 67.5 0.1 0.0 1.3 0.0 0.0 0.3 1.7 0.8 0.0 0.0 0.0 0.4 1.1 0.0 0.5 0.0 0.0 0.5 0.0 0.0 554.0 0.0 11.7 3060.6 0.6 0.0 0.0 0.4 0.8 1.0 0.0 9.2 0.6 0.0 13.4 0.1 306.6 0.0 400.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 7.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.8 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 27.3 0.3 2.2 0.0 0.0 172.1 156.1 0.2 0.0 1.8 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 11.1 0.0 0.0 0.4 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 1.3 0.2 0.3 6.8 390.7 0.0 1.2 0.0 0.0 3.3 CAMK2B "CAM2, CAMK2, CAMKB, CaMKIIβ" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 248.8;skeletal muscle: 132.5" "Cell type enriched" "Detected in many" 7 "Bipolar cells: 857.4" "Cancer enhanced" "Detected in many" "glioma: 6.0;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA 600000 "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 0.5 11.3 77.9 0.6 109.0 0.1 1.4 113.0 248.8 0.1 0.0 1.0 1.0 0.2 28.3 1.4 1.1 0.2 65.4 197.6 12.6 1.6 7.7 0.3 1.3 4.4 11.9 0.3 3.8 6.1 51.3 0.1 4.6 3.2 0.4 21.4 1.4 1.6 132.5 1.2 0.9 0.1 3.2 0.3 2.3 2.1 25.9 0.8 20.3 59.2 1.6 0.0 0.3 80.4 0.0 0.8 0.4 0.6 0.0 0.4 0.4 0.3 0.1 0.3 0.0 0.3 0.1 0.2 1.6 0.4 0.1 0.3 0.4 1.4 0.1 2.0 4.5 0.1 0.2 0.2 0.1 0.0 0.9 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.8 0.1 10.1 0.0 0.4 0.2 0.1 4.4 0.2 1.7 0.3 0.0 0.0 75.5 4.0 0.4 0.0 0.0 0.1 3.5 0.3 0.4 0.5 0.7 0.4 0.1 0.9 0.8 0.2 0.2 0.0 0.5 1.0 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 0.4 0.7 0.3 0.2 0.2 0.2 77.9 109.0 113.0 248.8 197.6 12.6 4.4 11.9 4.6 3.2 25.9 80.4 0.1 0.0 0.0 67.3 0.2 1.1 21.5 0.0 10.8 857.4 3.1 17.5 88.9 2.8 0.0 0.0 45.9 0.1 0.0 0.5 9.8 0.0 0.9 2.3 0.4 1.6 40.7 0.0 111.4 0.0 0.2 2.9 4.1 5.6 4.5 15.4 0.0 4.3 0.2 60.6 90.9 1.5 2.0 0.6 0.4 2.9 1.8 0.5 1.8 5.6 0.0 23.2 0.0 19.6 5.4 0.1 1.2 0.0 0.1 3.3 0.1 1.9 0.0 53.1 0.0 6.9 1.7 0.2 7.8 0.9 0.4 0.3 0.2 0.2 0.3 6.6 CAMK2N1 CaMKIINalpha ENSG00000162545 "Calcium/calmodulin dependent protein kinase II inhibitor 1" Q7Z7J9 1 20482391-20486210 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 461.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 640.5;Intestinal goblet cells: 431.4;Paneth cells: 367.7;Proximal tubular cells: 519.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6;MAIT T-cell: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Cell line enhanced" "Detected in many" "AN3-CA: 212.1;CAPAN-2: 199.1;Hep G2: 165.6;SK-BR-3: 159.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075200 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA075200: " "unprognostic (1.67e-1)" "unprognostic (2.70e-3)" "unprognostic (9.71e-3)" "unprognostic (3.13e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (1.37e-7)" "prognostic unfavorable (5.49e-4)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.77e-2)" "unprognostic (1.31e-1)" "unprognostic (7.48e-3)" "unprognostic (1.93e-2)" "unprognostic (1.40e-3)" "unprognostic (4.44e-2)" "unprognostic (1.19e-1)" "unprognostic (1.96e-2)" "unprognostic (1.31e-2)" 20.1 61.6 340.5 9.3 322.3 0.5 19.8 172.0 461.3 32.5 115.4 85.0 80.4 27.8 38.1 27.8 22.3 27.4 22.3 354.6 206.5 86.2 53.8 67.9 1.9 224.8 222.4 30.2 8.8 42.4 37.7 11.6 215.9 35.8 77.0 32.6 30.4 40.8 7.1 12.0 86.9 22.7 226.7 12.2 19.5 4.7 265.4 2.0 10.8 9.9 7.0 27.3 24.3 348.6 63.1 17.5 15.0 212.1 28.4 52.6 2.2 52.6 119.0 9.5 4.8 20.1 199.1 6.3 14.7 21.7 7.7 103.2 4.6 90.0 5.9 11.7 3.8 1.3 0.9 165.6 31.4 0.1 6.2 8.4 41.2 5.6 21.2 19.6 16.4 4.3 6.3 0.5 105.8 17.4 0.2 0.5 2.8 109.7 3.9 5.6 9.4 0.4 59.3 93.5 57.6 16.2 28.5 159.6 16.3 10.2 30.6 0.6 5.0 34.9 46.1 48.5 21.1 0.1 0.1 2.5 119.5 13.5 22.0 0.0 0.0 0.0 1.6 0.0 1.1 0.5 0.5 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 340.5 322.3 172.0 461.3 354.6 206.5 224.8 222.4 215.9 226.7 265.4 348.6 28.3 3.2 1.1 35.6 7.6 9.3 11.7 2.3 0.6 248.6 96.5 104.5 20.8 178.7 2.5 248.3 6.2 0.5 10.1 640.5 229.0 20.1 0.8 6.2 45.6 20.0 299.2 8.0 132.5 40.8 2.9 65.1 9.2 12.0 1.3 4.6 9.3 201.6 0.3 85.8 108.7 431.4 14.2 1.9 12.1 3.9 62.7 5.6 39.2 26.2 0.6 81.1 0.0 27.6 249.1 141.5 367.7 94.0 3.5 37.7 183.2 519.2 1.2 35.6 131.5 86.2 96.4 0.8 2.8 1.0 7.5 2.1 14.7 0.8 223.5 50.3 CAMK4 "CaMK-GR, CaMKIV" ENSG00000152495 "Calcium/calmodulin dependent protein kinase IV" Q16566 5 111223653-111494886 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Inflammatory response" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 70.4;lymphoid tissue: 55.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 70.9;Early spermatids: 306.2;Excitatory neurons: 212.2;Inhibitory neurons: 131.8;Late spermatids: 108.4;Oligodendrocyte precursor cells: 133.2;T-cells: 83.3" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 6 "basal ganglia: 30.6;cerebellum: 70.4" "Group enriched" "Detected in many" 4 "MAIT T-cell: 24.3;memory CD4 T-cell: 17.3;memory CD8 T-cell: 13.5;naive CD4 T-cell: 33.1;naive CD8 T-cell: 18.5;T-reg: 21.3" "Lineage enriched" "Detected in many" 23 "T-cells: 33.1" "Cell line enhanced" "Detected in many" "HDLM-2: 88.9;JURKAT: 61.3;MOLT-4: 27.9;SH-SY5Y: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004347, HPA011753, HPA017206" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nucleoli fibrillar center" "CAB004347: AB_626793, HPA011753: AB_1845950, HPA017206: AB_1845949" "unprognostic (2.99e-5)" "unprognostic (7.19e-2)" "unprognostic (3.43e-3)" "unprognostic (5.11e-2)" "unprognostic (4.75e-3)" "unprognostic (3.48e-2)" "unprognostic (7.66e-4)" "unprognostic (7.22e-3)" "unprognostic (2.49e-1)" "unprognostic (2.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (2.23e-5)" "unprognostic (2.42e-2)" "unprognostic (3.01e-2)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" 0.4 3.8 5.0 4.4 30.6 3.1 0.4 70.4 8.2 0.9 0.0 1.3 1.4 0.6 0.3 0.7 0.3 1.5 0.1 7.6 0.0 0.7 1.4 1.1 8.1 0.0 0.4 0.6 0.4 0.0 0.6 0.2 1.4 3.4 1.4 4.7 0.4 1.4 0.1 0.1 2.3 0.8 0.0 2.6 1.5 9.4 0.8 55.4 0.2 0.0 5.2 1.7 0.4 0.0 0.0 0.0 3.1 2.1 0.6 2.3 0.0 0.8 6.8 8.0 7.8 0.0 0.1 0.0 4.0 0.4 5.4 0.3 6.8 0.8 5.8 88.9 5.2 1.3 2.8 0.0 0.2 0.6 0.3 0.3 0.0 16.8 1.7 4.9 1.4 61.3 0.0 3.3 0.4 0.0 27.9 0.0 4.1 0.0 0.2 4.0 5.0 0.2 2.9 0.1 18.8 33.5 1.2 0.0 5.6 0.2 0.1 0.5 0.1 16.3 9.5 0.1 14.7 2.6 0.3 0.0 8.0 0.0 6.3 0.1 0.0 0.0 4.8 0.0 24.3 1.3 17.3 13.5 0.0 0.3 33.1 18.5 0.9 1.4 0.0 0.1 21.3 5.5 5.0 30.6 70.4 8.2 7.6 0.0 0.0 0.4 1.4 0.0 0.8 0.0 1.8 0.0 1.1 57.8 9.4 1.1 0.3 1.3 8.6 70.9 0.6 0.6 5.3 0.0 0.0 0.0 0.0 0.1 3.1 0.1 0.0 0.1 306.2 0.2 1.6 1.1 0.0 0.0 212.2 0.0 0.2 4.6 3.6 0.4 4.5 0.3 0.7 0.3 0.2 0.0 131.8 0.8 0.0 1.3 2.1 108.4 4.1 2.0 0.0 12.2 2.7 2.8 1.0 133.2 5.4 1.2 0.0 1.5 11.5 0.5 0.0 0.1 0.1 4.3 0.0 0.6 3.8 30.3 6.2 2.4 1.0 0.0 83.3 0.1 0.0 0.3 CAPG "AFCP, MCP" ENSG00000042493 "Capping actin protein, gelsolin like" P40121 2 85394753-85418432 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 548.8;Hofbauer cells: 1107.4;Macrophages: 432.1;monocytes: 432.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1136.5;classical monocyte: 1139.3;eosinophil: 712.7;intermediate monocyte: 431.6;memory B-cell: 575.6;myeloid DC: 1363.2;naive B-cell: 516.8;NK-cell: 605.5;plasmacytoid DC: 959.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 563.6;HMC-1: 972.7;SK-MEL-30: 722.2;THP-1: 513.5;U-937: 569.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018843, HPA019080, HPA019092" Enhanced Enhanced Nucleoplasm Yes No 5400000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA018843: AB_2669948, HPA019080: AB_1845979, HPA019092: AB_1845980" "unprognostic (2.82e-2)" "unprognostic (1.37e-1)" "unprognostic (8.80e-2)" "unprognostic (1.28e-2)" "unprognostic (4.37e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-5)" "unprognostic (8.83e-2)" "unprognostic (3.22e-2)" "unprognostic (1.54e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-1)" "prognostic favorable (2.96e-4)" "unprognostic (1.45e-1)" "unprognostic (7.68e-2)" "unprognostic (5.30e-3)" "unprognostic (7.89e-3)" 92.4 26.3 42.8 82.4 44.2 159.3 94.9 46.3 79.6 119.1 37.5 56.9 30.3 50.0 46.2 289.5 48.7 44.4 19.2 41.7 51.1 201.1 8.9 175.7 117.9 60.2 46.3 19.7 44.9 151.7 27.2 26.1 57.2 76.5 42.9 4.2 111.8 38.0 16.5 219.9 54.2 24.5 57.5 46.2 94.4 26.0 66.1 58.0 162.3 5.8 109.5 97.1 174.8 79.4 165.5 75.9 0.7 6.9 50.2 102.8 83.7 59.6 6.1 51.2 49.8 9.4 563.6 28.1 96.6 116.0 64.0 181.1 0.2 113.7 23.0 142.0 4.4 74.3 128.0 29.3 40.6 44.8 972.7 93.8 80.5 53.8 70.3 3.6 37.5 143.8 8.2 60.1 38.1 150.1 101.3 414.8 23.2 166.5 112.8 87.3 13.3 11.8 220.6 77.7 0.8 1.4 86.9 128.4 722.2 44.2 40.0 513.5 148.7 111.6 26.8 4.6 2.4 1.4 6.2 10.3 259.5 569.5 1.5 1136.5 1139.3 712.7 12.2 431.6 39.2 575.6 107.8 41.1 1363.2 516.8 30.5 13.9 162.9 605.5 131.3 959.7 122.1 977.9 42.8 44.2 46.3 79.6 41.7 51.1 60.2 46.3 57.2 57.5 66.1 79.4 6.6 19.2 24.5 3.3 84.7 121.2 167.5 265.0 60.9 0.8 86.8 70.4 1.3 51.5 119.6 316.3 0.0 34.3 91.5 211.0 211.3 113.8 4.1 33.0 10.3 16.2 28.8 16.0 0.2 91.5 324.0 34.7 124.9 63.9 548.8 1.2 3.6 1.1 1107.4 1.7 0.2 55.9 50.8 141.6 337.2 15.2 46.9 432.1 147.7 1.0 432.4 43.6 11.3 0.5 0.1 405.8 205.4 22.6 17.2 106.0 74.1 168.5 48.8 1.7 13.1 2.0 54.0 9.6 33.1 167.4 169.5 35.7 101.9 0.9 83.9 253.1 CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 276.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 516.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 9100000 "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favorable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" 44.8 43.1 27.8 51.9 26.1 66.5 48.4 29.7 30.1 80.9 28.3 78.6 80.4 56.3 27.5 276.2 92.3 55.5 53.1 27.7 33.0 53.1 44.3 56.9 57.0 41.4 31.5 44.5 71.7 36.6 40.8 56.2 43.4 62.1 57.6 9.6 118.7 67.4 84.8 125.1 88.1 45.3 33.9 50.2 65.5 6.1 37.9 49.5 71.5 55.3 86.4 83.4 117.4 27.4 285.6 147.9 42.9 97.2 77.9 104.3 127.0 84.1 144.2 103.0 74.9 94.8 250.2 71.2 136.0 179.3 111.1 409.8 60.9 366.9 32.2 76.4 44.1 170.8 80.4 93.7 76.2 40.6 228.0 107.3 196.8 85.9 43.2 92.6 178.5 50.6 103.1 55.9 87.4 181.8 83.1 130.6 120.5 145.2 133.8 80.7 43.0 43.2 138.1 516.5 76.2 55.7 87.4 331.4 80.3 45.8 142.8 77.9 147.1 73.1 50.5 159.0 38.5 33.8 26.9 86.6 127.5 48.8 82.3 87.6 57.5 77.9 39.4 51.2 31.0 30.8 30.7 35.8 48.4 31.7 17.6 24.9 33.1 34.8 30.4 38.1 35.9 74.8 27.8 26.1 29.7 30.1 27.7 33.0 41.4 31.5 43.4 33.9 37.9 27.4 27.3 25.6 27.9 21.5 39.6 59.9 127.3 120.5 56.9 10.7 44.7 36.6 22.0 74.4 81.0 77.3 20.9 238.5 61.4 184.2 39.2 180.5 0.5 41.9 26.3 31.3 44.3 58.3 15.9 115.8 111.7 39.6 57.6 58.2 46.9 48.6 37.9 36.7 88.7 21.9 15.2 76.9 59.0 51.2 34.0 2.0 43.5 67.1 48.0 14.0 112.7 38.5 61.8 6.6 1.9 179.4 124.1 50.8 17.7 78.6 155.6 34.6 71.1 16.2 39.5 25.3 36.7 0.5 2.8 102.0 68.9 196.6 40.2 35.4 125.3 156.6 CAPN13 FLJ23523 ENSG00000162949 "Calpain 13" Q6MZZ7 2 30722771-30820542 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.2;stomach 1: 28.5" "Cell type enhanced" "Detected in many" "Club cells: 76.6;Gastric mucus-secreting cells: 50.0;Proximal enterocytes: 35.2;Undifferentiated cells: 18.1;Urothelial cells: 19.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 9.3;SK-BR-3: 21.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029496, HPA029497, HPA030034" Uncertain Approved Nucleoplasm NA NA "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA029496: AB_2673072, HPA029497: AB_2673073, HPA030034: AB_2673281" "unprognostic (7.42e-2)" "unprognostic (1.19e-1)" "unprognostic (7.01e-3)" "unprognostic (1.96e-1)" "unprognostic (8.56e-2)" "unprognostic (1.51e-1)" "unprognostic (1.68e-1)" "unprognostic (1.32e-3)" "unprognostic (2.17e-1)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-1)" "unprognostic (1.96e-2)" "unprognostic (3.64e-1)" "unprognostic (3.32e-2)" "unprognostic (5.03e-2)" "unprognostic (4.28e-3)" 0.0 0.0 0.8 0.0 1.4 0.0 7.2 0.9 1.3 9.7 1.0 11.4 20.8 0.2 0.3 0.9 1.1 2.8 0.0 0.7 0.8 2.5 0.2 7.2 0.0 1.1 1.3 0.0 3.6 0.4 0.2 0.0 1.0 3.8 24.6 0.0 1.2 0.1 0.0 0.2 29.2 0.2 1.0 0.1 28.5 0.1 1.1 0.0 0.0 0.0 0.6 4.1 0.5 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 9.3 0.1 0.4 0.0 21.9 0.0 0.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.9 1.3 0.7 0.8 1.1 1.3 1.0 1.0 1.1 2.3 0.0 6.4 3.1 0.3 0.0 0.0 10.2 3.5 4.0 0.0 4.2 1.8 1.3 0.0 76.6 1.8 0.0 0.0 0.0 16.9 0.0 1.3 0.8 2.0 0.0 0.1 15.0 0.0 0.3 5.3 0.0 0.6 50.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 1.5 12.0 6.1 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 8.4 1.9 6.2 0.0 0.0 2.7 35.2 0.2 12.4 0.0 0.0 0.0 6.1 0.0 0.1 1.4 0.0 0.0 0.1 0.0 18.1 19.4 CAPN15 SOLH ENSG00000103326 "Calpain 15" O75808 16 527712-554636 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basophil: 4.7;neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011960 Uncertain Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA011960: AB_10610556" "unprognostic (4.11e-2)" "unprognostic (1.63e-1)" "unprognostic (1.14e-1)" "unprognostic (2.66e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-2)" "unprognostic (1.54e-3)" "unprognostic (8.31e-3)" "unprognostic (1.32e-1)" "unprognostic (1.24e-1)" "unprognostic (1.86e-1)" "unprognostic (4.02e-2)" "unprognostic (2.53e-3)" "unprognostic (2.54e-3)" "unprognostic (5.91e-2)" "unprognostic (1.83e-1)" "unprognostic (9.23e-3)" 13.0 12.0 3.6 7.2 2.5 8.1 10.8 11.6 6.2 12.2 0.2 20.2 16.3 13.4 0.4 18.5 13.2 1.6 11.2 3.2 0.2 18.4 17.2 15.3 5.1 4.1 1.0 13.2 24.8 2.2 15.2 2.6 1.4 12.3 2.3 1.1 12.6 2.8 14.9 22.3 22.7 1.2 0.2 21.2 16.5 18.7 2.1 2.8 11.7 0.9 2.5 12.5 12.8 0.8 16.8 21.5 3.0 9.3 1.7 3.4 46.2 17.5 4.6 4.9 3.3 28.2 12.1 24.0 16.3 3.2 5.0 21.9 2.0 6.9 1.8 25.2 37.1 20.2 25.7 17.6 7.3 23.8 27.3 3.9 4.0 4.9 2.2 2.9 5.3 14.7 37.6 7.1 1.6 25.9 27.1 26.0 26.7 8.6 20.2 46.5 8.7 24.2 3.3 11.0 19.6 17.8 11.7 16.2 10.2 1.8 13.3 24.7 26.2 15.3 21.4 15.7 22.0 18.2 11.0 21.3 6.7 13.8 9.7 4.7 1.3 0.8 0.3 0.8 0.1 0.4 0.1 0.4 0.3 2.3 0.1 0.2 16.2 1.1 1.3 0.5 0.2 0.3 3.6 2.5 11.6 6.2 3.2 0.2 4.1 1.0 1.4 0.2 2.1 0.8 7.6 3.2 8.4 10.1 5.9 8.9 5.7 6.2 3.4 12.1 7.6 6.6 3.1 8.6 5.6 7.3 16.7 3.7 22.3 54.3 1.9 6.2 16.5 6.1 8.9 8.7 4.2 1.7 10.6 15.7 4.4 6.9 20.4 13.3 7.0 10.8 8.9 16.5 6.8 20.2 11.3 26.9 8.2 12.0 6.8 6.2 7.5 8.2 1.8 7.5 6.5 9.1 23.7 10.6 7.8 14.3 37.1 4.5 5.8 13.4 33.1 5.7 4.6 11.2 0.0 10.2 5.2 5.3 7.4 5.8 8.0 2.5 9.2 9.6 25.9 11.6 CAPSL MGC26610 ENSG00000152611 "Calcyphosine like" Q8WWF8 5 35904288-35938779 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "fallopian tube: 110.9" "Cell type enhanced" "Detected in some" "Early spermatids: 167.1;Endometrial ciliated cells: 400.1;Late spermatids: 148.9;Respiratory ciliated cells: 709.5" "Cancer enriched" "Detected in many" 4 "endometrial cancer: 14.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 7.3;BJ hTERT+ SV40 Large T+ RasG12V: 6.2;HBF TERT88: 4.7;REH: 8.0;U-698: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA046811, HPA058495" Enhanced Approved Nucleoplasm,Microtubules No No "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Microtubules" "HPA046811: AB_2679819, HPA058495: AB_2683735" "unprognostic (1.16e-1)" "unprognostic (3.40e-2)" "unprognostic (2.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.20e-2)" "unprognostic (7.35e-2)" "unprognostic (1.29e-1)" "unprognostic (1.92e-3)" "unprognostic (4.42e-1)" "unprognostic (3.62e-4)" "unprognostic (1.46e-1)" "unprognostic (1.36e-2)" "unprognostic (1.52e-1)" 0.0 0.0 3.3 0.0 2.8 0.2 0.1 1.9 2.1 2.5 25.4 0.0 0.0 2.0 8.4 0.0 110.9 0.0 0.0 2.1 3.6 0.8 0.0 7.7 0.0 9.9 10.2 0.1 0.5 1.2 13.6 0.0 7.5 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 8.0 0.0 0.1 9.9 4.0 6.6 5.4 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.8 7.3 6.2 0.0 0.0 2.2 0.0 1.0 0.1 0.0 0.1 0.0 4.7 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 1.3 0.0 0.0 1.2 2.1 0.0 0.5 0.0 0.0 19.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 2.8 1.9 2.1 2.1 3.6 9.9 10.2 7.5 8.0 4.0 7.6 0.0 3.2 7.3 0.3 0.0 0.0 0.1 58.0 0.0 0.0 0.2 0.0 0.0 0.0 66.2 1.8 0.0 0.0 0.0 0.0 1.9 0.1 167.1 400.1 2.4 0.5 0.0 0.0 0.4 0.0 0.0 0.8 0.0 4.7 1.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 65.1 0.0 0.0 148.9 0.9 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.5 0.0 1.6 709.5 0.0 0.0 0.0 19.2 21.0 1.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 CAPZA1 ENSG00000116489 "Capping actin protein of muscle Z-line subunit alpha 1" P52907 1 112619805-112671616 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB045963 Approved NA NA 16000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB045963: AB_11126023" "unprognostic (7.06e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-3)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.54e-6)" "unprognostic (1.17e-3)" "unprognostic (3.15e-2)" "unprognostic (3.82e-3)" "unprognostic (4.59e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (2.42e-1)" "unprognostic (2.82e-1)" 73.7 49.1 42.5 115.3 43.6 156.4 55.7 46.4 51.7 48.3 45.7 86.1 67.9 43.1 61.5 96.3 42.9 59.1 27.9 40.5 49.7 41.1 73.1 65.4 154.0 51.6 49.3 30.6 35.5 39.6 21.4 85.4 51.2 42.4 95.0 37.2 38.5 37.4 25.4 92.4 70.8 63.9 49.1 105.2 70.9 71.1 50.6 118.2 48.1 22.1 187.7 97.3 52.8 57.5 308.0 88.9 148.4 120.7 180.6 207.9 186.5 237.7 245.3 236.7 210.9 120.7 126.9 319.6 174.8 277.6 108.0 142.6 199.9 251.3 293.4 245.5 100.2 279.0 141.8 148.7 212.8 507.3 376.5 224.6 186.5 230.7 219.2 140.5 268.1 143.2 287.3 191.6 335.6 177.2 262.8 222.6 146.3 179.7 180.3 192.5 292.0 158.8 207.9 221.3 102.2 109.6 274.3 246.9 192.6 118.2 127.8 441.6 305.8 192.8 191.6 317.7 292.2 135.0 134.2 359.8 331.4 381.5 450.4 396.9 254.5 319.7 172.1 385.9 194.5 198.3 188.8 209.1 207.9 145.0 105.4 171.0 524.7 145.9 434.0 164.6 252.5 369.9 42.5 43.6 46.4 51.7 40.5 49.7 51.6 49.3 51.2 49.1 50.6 57.5 59.5 28.9 49.0 59.4 186.0 180.9 73.7 87.4 63.2 31.2 73.3 35.3 22.0 54.3 69.0 101.2 25.0 138.8 194.9 152.4 92.0 94.9 380.4 62.1 95.4 78.0 61.1 104.5 48.3 111.9 206.8 72.1 59.1 86.0 92.0 48.8 83.2 74.5 233.1 43.7 47.8 101.5 52.9 320.0 361.0 210.2 57.2 211.9 122.7 54.4 236.5 33.5 125.7 55.8 73.7 168.9 135.7 55.3 137.2 105.7 89.0 88.8 71.4 31.2 65.7 42.8 79.6 166.3 67.7 110.2 237.8 184.0 196.7 73.9 110.3 147.0 CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3043867 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "B-cells: 34.9;dendritic cells: 47.2;Microglial cells: 49.6;NK-cells: 28.8;Pancreatic endocrine cells: 24.9;Plasma cells: 26.7;T-cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 31.4" "Cell line enhanced" "Detected in many" "Daudi: 122.7;K-562: 50.1;RT4: 91.4;U-698: 108.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA052984: AB_2682005" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (4.81e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.65e-2)" "unprognostic (5.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-8)" "unprognostic (3.74e-2)" "unprognostic (4.75e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.10e-4)" 1.3 3.1 6.9 21.8 1.5 18.5 1.2 1.8 1.5 2.3 1.0 2.4 3.7 1.3 0.2 1.3 2.2 8.8 1.0 1.3 4.9 1.6 1.6 4.7 47.3 4.2 8.4 1.3 1.4 0.7 0.9 0.5 3.7 1.4 2.3 0.2 3.3 1.6 0.6 0.7 18.3 0.6 3.0 31.5 7.5 1.7 14.0 20.9 1.5 0.2 29.5 17.1 1.3 4.6 16.7 2.6 0.1 0.1 0.0 0.0 12.2 0.1 0.0 0.5 0.0 32.4 35.5 122.7 29.2 0.0 0.0 27.2 0.0 0.4 0.3 42.1 1.1 0.1 3.1 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.8 23.1 13.3 50.1 0.0 0.0 0.3 4.7 0.0 44.9 20.6 0.1 5.9 0.1 30.7 11.4 91.4 0.3 1.5 0.1 0.2 0.1 17.7 0.2 2.5 15.4 0.2 11.8 0.1 0.1 12.3 0.1 108.0 0.0 0.0 0.2 0.5 0.0 0.0 7.7 0.0 7.2 5.4 4.4 5.2 0.9 6.2 2.9 5.3 0.2 5.5 0.0 31.4 3.5 2.9 6.9 1.5 1.8 1.5 1.3 4.9 4.2 8.4 3.7 3.0 14.0 4.6 0.5 0.0 0.0 0.7 34.9 0.0 0.3 0.3 0.6 0.6 0.3 0.4 2.0 0.0 0.3 1.8 0.0 0.0 47.2 0.7 0.0 4.6 0.2 0.4 0.3 0.6 0.0 0.8 2.1 5.3 0.0 1.6 14.3 0.7 5.7 8.6 0.4 0.2 1.5 0.0 1.6 0.3 0.0 2.4 1.8 0.4 0.3 5.4 3.6 49.6 1.0 0.1 28.8 1.0 0.6 24.9 0.0 0.0 26.7 0.3 0.0 0.1 1.0 0.2 0.0 0.3 0.9 1.5 0.2 0.0 0.3 0.0 28.6 4.5 0.4 8.1 CARD14 "BIMP2, CARMA2, PSORS2" ENSG00000141527 "Caspase recruitment domain family member 14" Q9BXL6 17 80169992-80209331 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.5;skin 1: 14.4;vagina: 7.3" "Cell type enhanced" "Detected in many" "Kupffer cells: 8.2;Microglial cells: 6.5;Oligodendrocytes: 11.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 5.2;SK-BR-3: 6.9;T-47d: 10.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA023388 Supported Aggresome,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Cytosol Aggresome "HPA023388: AB_1846020" "unprognostic (9.79e-3)" "unprognostic (3.86e-2)" "unprognostic (4.26e-1)" "unprognostic (1.05e-5)" "unprognostic (2.65e-2)" "unprognostic (1.37e-2)" "unprognostic (2.92e-4)" "unprognostic (1.92e-1)" "unprognostic (1.47e-1)" "unprognostic (2.63e-1)" "unprognostic (3.01e-1)" "unprognostic (5.48e-2)" "unprognostic (1.62e-8)" "unprognostic (2.52e-1)" "unprognostic (2.06e-1)" "unprognostic (2.38e-1)" "unprognostic (2.34e-1)" 0.3 1.1 0.3 0.6 0.3 0.2 2.6 0.1 0.4 4.9 0.1 0.4 1.1 0.3 0.3 13.5 0.6 0.4 0.2 0.3 0.3 0.6 0.3 0.6 0.6 0.5 0.3 0.4 0.4 0.0 0.5 0.2 0.4 2.5 0.0 0.3 3.3 0.0 0.4 14.4 0.8 0.0 0.1 1.5 0.5 1.2 0.4 0.0 0.5 0.0 1.6 1.0 7.3 0.4 1.7 0.4 0.3 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.8 0.6 0.0 1.9 0.2 0.0 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 5.2 0.0 0.0 0.1 1.0 0.1 0.0 1.1 0.4 0.0 1.6 0.4 0.1 0.0 6.9 0.8 0.4 10.4 0.0 0.4 0.1 0.3 0.3 0.0 2.2 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.4 0.3 0.3 0.5 0.3 0.4 0.1 0.4 0.4 0.3 0.0 1.1 1.6 0.1 1.8 4.0 2.1 0.0 0.6 4.5 2.2 0.9 2.8 2.0 0.0 0.0 0.2 0.2 0.1 0.0 0.6 0.7 1.3 0.2 0.9 0.0 0.0 0.9 2.2 0.4 0.5 0.0 1.5 0.0 0.4 0.7 0.0 0.8 0.0 0.8 0.1 0.0 8.2 0.8 0.1 0.3 0.6 1.8 6.5 0.1 1.4 0.0 1.0 11.6 1.8 0.1 0.4 0.1 3.2 0.9 0.3 3.6 0.8 0.0 0.2 0.3 1.3 0.4 5.0 3.0 1.5 0.3 0.7 0.5 3.6 CARD9 ENSG00000187796 "Caspase recruitment domain family member 9" Q9H257 9 136361903-136373681 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 14.1;Hofbauer cells: 21.2;Horizontal cells: 15.2;Kupffer cells: 18.8;Langerhans cells: 12.9;Macrophages: 22.3;monocytes: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 57.6;non-classical monocyte: 50.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 22.5;HMC-1: 69.7;NB-4: 50.0;THP-1: 63.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059502 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA059502: AB_2684042" "unprognostic (7.03e-2)" "unprognostic (5.61e-2)" "unprognostic (8.62e-3)" "unprognostic (2.06e-2)" "unprognostic (2.75e-1)" "unprognostic (2.11e-2)" "unprognostic (3.89e-3)" "unprognostic (6.36e-2)" "unprognostic (2.64e-1)" "unprognostic (1.55e-2)" "unprognostic (7.68e-3)" "unprognostic (6.97e-2)" "unprognostic (2.02e-6)" "unprognostic (2.52e-1)" "unprognostic (4.87e-3)" "unprognostic (3.06e-1)" "unprognostic (1.06e-1)" 1.2 1.3 0.5 4.7 0.5 13.0 1.2 2.5 1.0 2.0 0.3 1.0 1.3 0.8 0.4 1.0 1.8 1.0 0.5 0.5 0.7 1.0 0.9 3.4 1.2 1.9 0.9 0.3 0.5 0.1 0.8 0.9 1.3 1.8 0.4 0.2 1.1 1.0 0.2 2.7 1.8 1.1 1.4 9.9 0.6 0.4 1.1 0.4 0.4 0.0 1.5 1.2 1.1 1.7 0.1 0.0 0.3 0.0 0.0 0.0 4.6 9.5 0.3 0.2 0.0 0.7 0.0 0.0 0.1 3.5 0.0 0.0 0.3 0.0 0.1 0.0 0.2 22.5 0.1 6.8 4.9 12.2 69.7 0.0 0.1 0.2 0.2 0.0 0.1 0.0 5.3 0.0 0.0 0.2 0.0 50.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 12.3 0.0 16.0 0.1 0.0 4.1 63.7 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 16.0 0.0 6.9 34.5 11.5 0.0 57.6 0.9 0.0 0.0 0.0 26.0 0.0 0.0 0.0 2.3 0.7 50.5 0.1 0.5 14.1 0.5 0.5 2.5 1.0 0.5 0.7 1.9 0.9 1.3 1.4 1.1 1.7 0.8 0.0 4.6 4.6 1.1 1.8 0.6 0.3 3.4 0.2 4.2 4.3 2.6 0.0 4.9 3.7 0.0 0.4 2.2 0.4 1.9 0.1 1.0 1.2 14.1 1.1 0.0 2.5 2.1 0.0 0.4 2.1 1.5 1.4 10.8 0.4 0.7 0.1 21.2 15.2 1.1 0.0 0.0 18.8 12.9 6.9 0.3 22.3 1.8 6.5 16.3 4.6 3.1 0.0 0.2 0.0 0.1 0.0 1.4 0.1 0.0 0.3 0.6 0.9 0.0 0.3 1.5 1.0 1.5 0.9 1.7 0.4 1.4 0.2 0.2 0.6 CARHSP1 "CRHSP-24, CSDC1" ENSG00000153048 "Calcium regulated heat stable protein 1" Q9Y2V2 16 8852942-8869012 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 422.7" "Group enriched" "Detected in all" 7 "Early spermatids: 2062.2;Late spermatids: 6999.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051911 Enhanced NA Yes 280000 "Cluster 10: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA051911: AB_2681660" "unprognostic (4.08e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.15e-1)" "unprognostic (2.08e-3)" "unprognostic (8.57e-2)" "unprognostic (1.88e-3)" "unprognostic (2.03e-1)" "unprognostic (3.29e-1)" "unprognostic (2.61e-1)" "unprognostic (7.19e-3)" "unprognostic (1.76e-3)" "unprognostic (5.94e-2)" "unprognostic (1.10e-1)" "unprognostic (2.61e-1)" "prognostic favorable (7.24e-4)" 101.4 132.5 49.4 33.7 75.0 70.0 67.7 46.8 58.4 101.7 46.5 46.4 31.3 38.2 13.5 193.7 51.0 33.8 48.2 50.1 50.8 109.6 188.2 116.7 46.9 56.1 49.7 68.5 54.8 9.8 33.2 59.2 51.2 35.3 25.6 3.0 110.7 13.9 17.4 34.5 47.1 24.2 47.6 56.7 52.5 422.7 51.0 59.6 35.9 21.3 59.4 45.8 101.7 60.4 84.2 134.8 200.2 40.3 52.1 83.0 98.9 110.7 93.5 92.9 117.8 95.4 224.6 109.1 70.2 83.5 70.9 82.0 79.3 87.9 65.4 87.9 102.1 34.5 108.1 369.8 177.5 59.2 84.6 181.7 40.0 91.8 60.7 87.8 92.6 241.5 94.5 136.1 120.5 152.0 313.5 147.6 124.6 89.0 82.2 367.0 245.9 179.3 75.5 56.0 119.0 153.2 104.9 106.1 104.0 112.4 134.9 60.3 99.9 77.8 144.9 94.6 57.4 67.6 77.4 135.0 173.9 71.9 134.9 81.6 29.6 35.8 25.8 14.3 16.1 17.5 25.0 25.3 25.8 28.6 17.0 23.7 89.2 41.6 19.0 47.4 62.8 20.8 49.4 75.0 46.8 58.4 50.1 50.8 56.1 49.7 51.2 47.6 51.0 60.4 166.3 25.6 9.1 19.6 48.9 42.7 67.2 158.4 22.8 8.0 71.4 38.0 6.0 221.6 86.4 82.8 6.2 141.5 65.1 152.6 54.8 619.1 2062.2 101.9 82.0 145.3 144.9 147.5 4.4 241.8 312.6 86.4 42.8 114.4 39.3 118.0 128.8 323.5 70.5 11.8 5.9 107.7 91.6 62.4 55.3 6999.5 96.3 36.1 58.7 9.4 66.5 7.7 121.5 8.0 25.6 340.0 179.5 73.0 63.9 139.3 174.2 479.0 70.9 11.2 111.7 31.2 95.5 72.7 52.7 84.2 42.1 153.5 65.1 17.0 108.4 169.8 CARMIL2 "LRRC16C, RLTPR" ENSG00000159753 "Capping protein regulator and myosin 1 linker 2" Q6F5E8 16 67644988-67657569 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.4;intestine: 13.4;lymphoid tissue: 21.6" "Group enriched" "Detected in some" 4 "B-cells: 3.6;dendritic cells: 3.7;T-cells: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 64.2;JURKAT: 47.3;MOLT-4: 64.6;REH: 105.6;RPMI-8226: 58.4;U-698: 107.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041402 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA041402: AB_10795591" "unprognostic (1.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.35e-2)" "unprognostic (6.37e-2)" "unprognostic (5.47e-3)" "unprognostic (4.27e-4)" "unprognostic (1.38e-2)" "unprognostic (1.44e-1)" "unprognostic (3.85e-2)" "unprognostic (1.52e-1)" "unprognostic (7.90e-5)" "unprognostic (4.07e-2)" "unprognostic (5.14e-10)" "unprognostic (2.25e-1)" "unprognostic (1.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.57e-2)" 0.9 0.5 5.9 12.5 6.3 5.9 0.5 4.5 11.4 0.4 2.4 2.0 1.8 0.3 0.1 0.9 0.5 1.2 0.3 9.8 5.1 0.9 0.8 1.7 21.6 5.6 4.0 0.2 0.4 0.1 4.5 0.2 5.4 0.8 0.7 0.3 1.4 0.1 0.0 0.4 13.4 0.2 3.4 19.9 1.9 0.9 4.9 20.9 1.2 0.0 10.9 1.5 0.7 6.8 0.2 0.1 0.1 0.3 0.0 0.1 18.1 0.6 0.0 0.5 0.0 9.6 0.6 64.2 1.1 0.0 0.1 0.1 6.0 0.0 0.0 14.3 7.5 3.8 0.3 1.2 0.5 7.1 0.6 0.1 0.0 0.0 0.1 0.1 0.0 47.3 0.9 1.0 0.0 1.1 64.6 32.2 10.7 0.3 0.3 105.6 0.1 58.4 0.0 0.0 15.9 1.7 0.1 0.2 0.5 1.5 0.4 1.9 0.2 0.9 2.0 0.1 0.4 17.6 33.4 107.2 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.7 0.1 0.0 0.4 0.2 0.1 0.0 0.4 0.0 0.3 0.7 0.1 5.9 6.3 4.5 11.4 9.8 5.1 5.6 4.0 5.4 3.4 4.9 6.8 0.4 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.9 0.2 0.0 0.0 CARMIL3 "BC008134, C14orf121, crml-1, LRRC16B" ENSG00000186648 "Capping protein regulator and myosin 1 linker 3" Q8ND23 14 24052009-24069729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 3.6;pituitary gland: 8.1;skin 1: 3.9;testis: 2.2" "Cell type enhanced" "Detected in single" "Collecting duct cells: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 5.5;HMC-1: 3.7;Karpas-707: 3.3;SCLC-21H: 5.4;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030596 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA030596: AB_10603012" "unprognostic (2.67e-2)" "unprognostic (2.07e-3)" "unprognostic (1.50e-1)" "unprognostic (3.09e-2)" "unprognostic (6.17e-2)" "unprognostic (1.29e-4)" "unprognostic (6.13e-2)" "unprognostic (8.92e-4)" "unprognostic (4.02e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-4)" "unprognostic (4.49e-2)" "unprognostic (1.17e-1)" "unprognostic (7.01e-2)" "unprognostic (1.25e-2)" "unprognostic (4.19e-1)" "unprognostic (2.16e-1)" 0.1 0.3 2.0 0.3 1.5 0.2 0.3 3.6 2.1 0.3 0.0 0.5 0.5 0.2 0.0 0.6 0.1 0.3 0.1 1.9 1.3 0.7 0.2 0.3 0.3 2.0 1.4 0.1 0.7 0.0 8.1 0.0 2.0 0.3 0.1 1.0 0.6 0.0 0.0 3.9 0.7 0.0 0.5 0.5 0.3 2.2 1.9 0.1 0.5 0.0 0.4 0.1 0.5 1.8 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.2 0.8 0.0 0.3 0.1 0.1 0.4 0.0 0.0 0.0 0.0 5.4 2.6 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 3.6 2.1 1.9 1.3 2.0 1.4 2.0 0.5 1.9 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 CASK "CAGH39, FGS4, LIN2, TNRC8" ENSG00000147044 "Calcium/calmodulin dependent serine protein kinase" O14936 X 41514934-41923554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 135.8;Oligodendrocyte precursor cells: 447.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 47.1" "Lineage enriched" "Detected in many" 10 "granulocytes: 47.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001949, HPA023857" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Cytosol "CAB001949: , HPA023857: AB_1846035" "unprognostic (6.30e-2)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (2.48e-3)" "unprognostic (1.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.42e-3)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (5.85e-3)" "prognostic unfavorable (6.11e-5)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.72e-2)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "unprognostic (2.85e-2)" 10.2 11.1 13.6 11.9 12.9 7.3 15.7 12.3 11.1 11.6 12.4 25.3 32.1 11.1 9.4 13.7 10.5 18.5 6.8 14.2 17.1 16.4 13.4 12.2 12.5 13.2 19.4 13.5 12.8 11.8 6.3 16.3 15.7 10.6 27.3 19.8 13.2 8.3 5.0 9.3 31.9 12.0 15.4 12.4 19.8 3.6 25.2 15.4 10.6 6.1 10.4 15.3 8.8 18.0 27.4 32.5 31.4 19.1 21.6 18.6 10.9 23.2 18.7 13.2 12.3 72.3 42.6 0.4 12.0 29.3 23.8 52.3 35.2 23.2 22.8 25.4 20.9 0.6 27.7 26.2 22.1 4.4 3.6 19.8 63.2 25.1 30.1 27.5 11.6 15.3 2.2 21.3 30.2 30.9 8.4 2.2 29.7 37.6 22.6 12.7 79.8 13.2 31.2 54.8 29.7 15.6 43.7 17.7 13.9 52.7 19.0 0.8 14.2 24.4 25.8 22.1 13.3 7.6 5.2 9.5 24.4 3.1 16.9 47.1 1.5 8.7 0.8 1.1 0.8 0.7 0.9 1.3 0.4 0.9 1.2 1.1 1.7 4.3 0.7 0.5 4.5 0.6 13.6 12.9 12.3 11.1 14.2 17.1 13.2 19.4 15.7 15.4 25.2 18.0 13.0 12.8 20.4 101.9 8.8 32.6 42.7 11.1 8.0 42.2 23.7 16.5 7.8 8.6 14.6 7.3 22.9 2.0 12.1 25.8 50.9 13.7 0.9 9.6 24.1 16.0 13.8 0.8 96.6 14.5 0.7 18.8 18.8 11.9 0.0 17.4 8.9 15.0 21.3 50.5 135.8 28.7 14.2 2.8 21.5 1.0 9.9 10.7 10.6 60.0 2.5 9.3 0.0 447.8 59.7 22.1 24.1 9.4 7.0 16.4 35.2 20.9 15.7 25.7 19.7 38.2 20.6 2.9 2.1 13.9 32.5 1.6 26.5 47.7 41.8 33.2 CASP14 "MGC119078, MGC119079, MICE" ENSG00000105141 "Caspase 14" P31944 19 15049480-15058293 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Hydrolase, Protease, Thiol protease" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "skin 1: 486.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 96.0" "Cancer enhanced" "Detected in many" "cervical cancer: 62.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "hTCEpi: 49.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010059, HPA027062" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3600000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" Mitochondria "CAB010059: AB_626800, HPA027062: AB_2672101" "unprognostic (1.17e-2)" "unprognostic (6.44e-3)" "unprognostic (6.22e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (9.42e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (5.96e-4)" "unprognostic (2.68e-1)" "unprognostic (4.30e-2)" "unprognostic (1.99e-1)" "unprognostic (1.97e-1)" 0.6 0.0 0.1 0.0 0.4 0.4 7.8 0.4 0.2 3.9 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.8 0.0 0.1 1.1 4.2 1.4 486.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.0 0.0 0.0 0.0 0.0 19.9 1.0 1.1 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.4 0.2 0.2 0.1 0.3 0.1 0.3 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 19.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 96.0 0.7 0.1 0.0 0.0 0.8 CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1056.7" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 777.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "HSkMC: 13.6" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in all" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" 31.9 3.0 3.5 6.4 2.3 0.0 8.9 2.8 4.0 8.0 2.0 59.8 3.3 17.2 6.5 38.5 14.7 6.6 1056.7 1.8 3.6 3.5 0.6 5.3 0.8 1.9 4.8 5.3 1.2 1.6 0.9 1.6 2.1 13.8 17.0 0.3 7.6 20.2 182.1 4.9 9.1 39.1 1.9 0.8 14.2 1.5 6.4 1.6 4.1 165.0 1.3 43.9 6.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 2.3 2.8 4.0 1.8 3.6 1.9 4.8 2.1 1.9 6.4 1.9 2.7 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.6 0.2 0.1 0.4 777.8 0.0 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 15.5 0.3 0.0 4.8 0.0 0.0 0.7 0.0 0.3 17.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 20.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 1.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 92.1 11.0 73.4 0.1 0.4 0.2 0.3 0.0 0.1 0.0 0.0 0.0 CBARP "BARP, C19orf26, DOS, MGC40084" ENSG00000099625 "CACN subunit beta associated regulatory protein" Q8N350 19 1228287-1238027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.3;pituitary gland: 22.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 21.8;Early spermatids: 55.9;Late spermatids: 97.4;Spermatocytes: 54.8" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012777 Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA012777: AB_2067005" "unprognostic (1.31e-1)" "unprognostic (4.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.10e-2)" "unprognostic (3.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.54e-5)" "unprognostic (3.48e-1)" "unprognostic (2.17e-1)" "unprognostic (4.58e-2)" "unprognostic (2.86e-3)" "unprognostic (3.03e-1)" "unprognostic (5.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.12e-1)" "unprognostic (2.40e-1)" "unprognostic (7.42e-5)" 1.4 2.6 6.0 0.1 9.8 0.0 0.4 2.0 15.3 0.7 0.0 0.6 0.1 0.5 0.0 1.4 0.5 0.1 1.7 12.3 3.1 2.3 0.3 1.0 0.0 5.6 1.3 4.9 0.4 0.0 22.3 0.1 1.3 0.8 0.0 0.3 0.4 0.1 0.4 3.1 0.2 0.0 0.0 0.1 0.4 1.7 1.8 0.0 0.6 0.0 0.0 0.3 0.9 0.0 0.3 0.4 1.1 3.1 0.1 0.5 0.4 2.7 0.8 0.5 0.5 1.1 0.1 0.0 2.7 0.5 0.3 0.9 0.4 0.6 0.1 0.5 0.7 0.1 1.1 0.9 1.4 0.0 1.0 0.6 0.2 0.6 0.1 0.5 0.4 0.5 1.7 0.0 0.3 2.3 0.0 0.6 1.6 0.1 1.2 2.0 0.4 0.2 0.1 0.2 1.4 4.2 0.0 0.0 3.1 0.1 0.4 0.5 1.2 0.7 2.6 2.3 0.7 0.1 0.2 0.0 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 9.8 2.0 15.3 12.3 3.1 5.6 1.3 1.3 0.0 1.8 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 1.2 21.8 1.7 1.8 0.0 1.5 0.0 0.0 2.1 0.0 0.6 0.0 1.9 0.1 55.9 0.9 2.2 0.7 0.0 0.0 0.0 0.2 0.1 1.2 1.1 1.6 0.0 0.9 1.4 0.1 0.3 3.3 0.0 0.0 0.0 0.8 0.0 97.4 1.8 1.2 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.9 0.0 0.2 0.0 1.7 0.0 0.7 1.4 54.8 7.0 1.1 0.0 0.0 0.3 0.1 0.0 0.3 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800652 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.3;intestine: 50.9;skin 1: 42.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 108.6;Pancreatic endocrine cells: 95.0;Paneth cells: 108.1;Proximal enterocytes: 154.6;Undifferentiated cells: 67.1;Urothelial cells: 76.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 43.6;BEWO: 28.9;CACO-2: 28.3;CAPAN-2: 56.9;HaCaT: 41.0;HBEC3-KT: 34.8;hTCEpi: 26.0;OE19: 37.3;RT4: 34.7;SK-BR-3: 31.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Aggresome "CAB008087: AB_2228531, HPA035266: AB_2674542" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.1 0.0 3.1 0.0 0.0 5.1 0.0 0.1 8.0 0.0 25.0 50.9 0.9 0.1 39.3 2.5 4.4 0.0 0.0 0.0 7.4 21.1 1.3 0.0 0.0 0.0 0.1 20.6 1.6 0.5 0.4 0.0 11.8 11.7 0.1 13.3 2.4 0.1 42.4 38.6 0.6 0.0 0.0 17.7 0.7 0.0 0.3 1.7 0.0 4.0 8.3 18.4 0.0 43.6 0.0 0.0 0.1 0.0 0.0 28.9 0.0 0.0 0.0 0.0 28.3 56.9 0.0 0.0 0.0 0.0 41.0 0.0 34.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 37.3 0.0 0.0 0.0 0.0 0.0 34.7 0.4 0.1 0.0 31.1 0.0 0.2 22.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 15.0 44.0 30.8 16.5 0.0 9.3 7.4 0.2 4.3 27.7 7.3 0.0 5.8 0.2 108.6 1.9 53.8 0.1 7.0 1.3 0.9 17.4 0.0 0.4 48.9 2.3 0.5 59.7 15.5 0.0 0.0 0.0 11.1 0.3 0.0 0.9 40.0 18.3 0.0 1.4 0.3 0.0 0.4 0.0 0.0 0.6 0.0 0.0 1.0 0.3 95.0 108.1 0.0 0.1 34.4 154.6 17.2 9.8 0.0 0.0 0.0 1.3 0.0 2.6 29.9 25.7 2.5 0.7 0.0 67.1 76.9 CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 114.2;testis: 31.9" "Cell type enhanced" "Detected in some" "Early spermatids: 100.9;Late spermatids: 291.0;Spermatocytes: 61.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.5" "Region enriched" "Detected in all" 4 "cerebellum: 114.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "NTERA-2: 40.0;SCLC-21H: 126.0" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in many" 13 "cerebellum: 369.4" "Secreted in brain" NA NA 6000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.39e-2)" "unprognostic (1.88e-2)" "unprognostic (1.53e-1)" "unprognostic (3.16e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (9.65e-3)" "unprognostic (1.18e-2)" "unprognostic (6.31e-2)" "unprognostic (1.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.04e-2)" "unprognostic (7.68e-2)" "unprognostic (2.45e-1)" "unprognostic (1.06e-2)" "prognostic favorable (7.10e-4)" "unprognostic (1.60e-2)" 11.8 1.0 4.6 0.2 3.2 0.0 3.8 114.2 7.1 2.1 0.9 0.7 1.0 5.8 0.4 1.0 1.3 7.5 4.6 2.4 23.4 0.2 1.0 0.1 0.8 10.7 18.4 1.3 2.8 0.2 4.2 0.0 12.7 0.5 0.7 3.5 0.6 0.6 0.9 0.8 1.3 1.7 4.8 0.1 0.7 31.9 27.0 0.2 2.3 1.7 2.8 1.4 0.5 5.4 0.0 0.0 0.6 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 2.7 2.6 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 126.0 3.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.2 114.2 7.1 2.4 23.4 10.7 18.4 12.7 4.8 27.0 5.4 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.3 2.2 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 100.9 0.1 2.4 6.7 13.2 0.0 0.6 0.4 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 4.7 0.5 0.0 0.0 0.0 291.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.5 0.4 0.2 0.0 0.4 0.0 0.1 0.3 0.0 0.0 1.8 26.3 0.1 19.2 61.7 5.8 0.0 0.1 0.0 0.0 8.8 0.2 0.0 CBR1 "CBR, SDR21C1" ENSG00000159228 "Carbonyl reductase 1" P16152 21 36069941-36073166 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 583.9" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 524.2;Distal tubular cells: 757.2;Proximal enterocytes: 1270.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018433, CAB034291" Enhanced Approved Nucleoplasm,Cytosol NA NA 12000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 45: Intestine - Brush border" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Cytosol "CAB034291: AB_2070856, HPA018433: AB_1846109" "prognostic favorable (2.18e-4)" "unprognostic (9.78e-2)" "unprognostic (3.25e-2)" "unprognostic (2.14e-1)" "unprognostic (6.47e-3)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (6.37e-2)" "unprognostic (4.56e-2)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (4.00e-1)" "prognostic favorable (4.75e-4)" "unprognostic (2.37e-1)" "unprognostic (2.47e-1)" "unprognostic (6.13e-3)" "unprognostic (2.47e-2)" 32.4 95.3 150.0 25.6 200.0 10.1 29.5 186.1 174.1 52.7 207.0 68.6 583.9 41.3 50.5 189.5 34.6 47.1 29.5 154.6 166.7 125.6 252.8 41.1 28.3 173.1 175.1 28.8 36.1 38.6 35.3 27.6 175.6 48.7 50.9 10.2 101.8 42.2 33.6 111.8 345.9 34.4 166.2 39.9 133.5 18.1 180.3 22.7 46.4 23.3 36.7 51.0 85.3 266.6 114.4 180.4 22.6 55.9 115.0 115.3 1.2 123.6 97.0 72.4 86.4 68.9 67.8 28.2 78.7 128.1 137.3 84.6 46.3 132.3 55.7 133.8 95.3 82.5 105.1 48.1 65.7 49.1 77.5 56.1 165.6 70.7 30.8 83.0 78.4 0.0 0.0 21.3 67.6 121.2 24.7 50.7 0.4 0.0 123.3 0.4 0.4 80.5 195.7 60.9 60.5 52.1 121.3 186.3 157.3 17.6 86.1 69.4 71.1 78.8 30.8 202.9 96.1 131.8 268.9 0.7 144.0 48.6 115.6 7.1 134.0 68.6 64.4 198.5 54.6 67.2 79.7 60.8 109.6 61.2 102.6 75.4 9.2 77.3 156.9 39.6 89.0 162.1 150.0 200.0 186.1 174.1 154.6 166.7 173.1 175.1 175.6 166.2 180.3 266.6 26.4 121.8 69.3 17.9 22.5 128.2 63.1 295.2 524.2 11.6 27.7 98.8 20.9 77.2 117.1 95.6 2.1 116.6 15.7 91.2 757.2 93.7 8.9 31.7 45.5 23.1 38.6 32.0 6.5 70.0 80.4 65.7 127.4 45.1 34.9 30.8 41.7 277.2 85.1 3.3 6.8 94.4 396.7 66.6 27.5 4.3 122.7 49.5 90.7 4.7 79.2 69.8 23.7 16.6 128.2 91.8 146.6 132.4 41.3 66.4 1270.3 326.0 121.2 8.3 26.3 51.3 90.7 5.8 17.4 403.5 123.6 89.2 30.7 55.6 145.8 55.0 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 CCDC120 JM11 ENSG00000147144 "Coiled-coil domain containing 120" Q96HB5 X 49053572-49069857 "Cancer-related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;skin 1: 29.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 20.9;BEWO: 28.6;HaCaT: 19.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000561 Uncertain Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA000561: AB_2244190" "unprognostic (1.65e-1)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (7.59e-3)" "unprognostic (1.80e-3)" "unprognostic (1.08e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.72e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (4.85e-2)" "unprognostic (2.64e-2)" "unprognostic (3.82e-3)" "unprognostic (4.54e-3)" "unprognostic (2.34e-3)" 3.1 2.6 5.2 2.1 5.0 2.3 4.4 7.6 6.4 10.6 4.5 5.2 8.7 4.4 5.7 35.9 5.0 2.5 1.8 5.0 4.8 9.1 6.6 4.3 2.0 3.9 4.0 6.3 8.0 3.8 9.3 4.0 3.9 7.7 2.2 2.0 12.0 4.0 0.7 29.3 7.4 1.6 3.0 3.8 6.8 3.4 4.9 2.9 6.0 0.5 3.9 5.3 16.1 3.5 20.9 2.8 4.5 0.2 0.0 0.0 28.6 0.7 1.0 1.5 2.4 6.9 8.7 0.8 3.2 1.2 3.4 19.5 3.4 11.7 0.1 5.4 6.6 2.0 5.0 2.4 1.5 0.1 3.4 2.5 9.0 1.9 0.5 3.1 2.5 5.4 2.9 0.2 0.0 17.5 7.5 0.5 5.1 9.8 0.1 6.6 3.3 2.0 8.8 11.0 6.0 4.7 3.6 7.2 2.2 6.1 17.7 2.8 1.2 0.1 5.2 0.2 0.2 6.6 4.8 0.1 0.2 0.1 0.9 1.1 0.2 0.5 0.3 0.0 0.2 0.2 0.4 0.3 0.0 0.6 0.4 0.3 1.0 0.4 0.1 0.6 0.1 0.1 5.2 5.0 7.6 6.4 5.0 4.8 3.9 4.0 3.9 3.0 4.9 3.5 1.7 6.4 3.1 2.0 2.5 5.1 3.5 7.1 4.0 6.8 8.2 5.6 1.3 4.3 6.0 12.9 4.2 12.7 2.2 5.6 0.0 5.1 0.1 8.5 2.2 2.7 6.0 1.7 4.8 6.5 3.2 2.9 9.7 11.5 0.0 4.9 2.5 2.5 2.3 10.1 6.2 6.2 2.0 1.2 1.5 0.5 2.1 0.9 0.0 2.8 0.4 3.3 2.1 2.5 0.7 14.4 8.3 1.2 1.5 6.3 9.0 3.1 5.0 6.8 0.0 2.6 1.5 1.4 2.4 9.0 9.2 16.8 2.3 2.3 4.6 11.4 CCDC137 MGC16597 ENSG00000185298 "Coiled-coil domain containing 137" Q6PK04 17 81666737-81673904 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052637, HPA053914" Uncertain Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitotic chromosome" "HPA052637: AB_2681894, HPA053914: AB_2682306" "unprognostic (3.04e-1)" "unprognostic (5.82e-2)" "unprognostic (1.76e-1)" "unprognostic (3.07e-2)" "unprognostic (1.68e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (8.32e-4)" "unprognostic (2.21e-2)" "unprognostic (8.33e-3)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (4.26e-2)" "unprognostic (2.01e-1)" "unprognostic (3.93e-1)" "unprognostic (1.39e-1)" 8.2 9.5 13.8 12.3 13.7 17.7 7.6 13.5 17.5 10.7 14.2 9.3 11.4 7.5 5.5 23.1 7.8 6.1 6.5 13.7 13.8 10.2 10.8 7.7 16.3 14.4 14.3 6.7 8.2 7.0 6.2 7.7 14.7 11.7 5.8 2.8 9.9 6.4 7.7 22.8 10.7 6.0 13.4 15.6 8.8 10.4 14.5 11.8 7.8 4.5 11.5 9.8 13.8 14.3 38.0 62.8 21.5 35.3 13.9 13.1 35.2 41.6 19.7 53.0 30.6 55.1 22.8 33.8 22.4 21.2 36.6 47.9 34.5 43.8 30.6 19.4 51.7 51.6 30.1 48.0 20.7 46.6 37.5 19.8 26.3 47.6 26.3 14.6 37.4 41.1 53.3 19.1 28.3 34.5 45.7 56.6 46.9 32.9 59.8 55.4 34.6 24.1 19.8 29.6 45.1 57.7 41.1 87.8 37.1 28.9 58.8 48.3 27.8 82.0 53.5 34.9 65.9 53.1 28.7 36.8 30.8 42.9 48.8 2.2 7.7 11.7 11.5 9.6 6.3 10.4 8.7 8.8 7.5 13.2 9.2 8.8 3.3 13.1 11.9 12.9 9.8 5.9 13.8 13.7 13.5 17.5 13.7 13.8 14.4 14.3 14.7 13.4 14.5 14.3 17.9 22.4 17.0 5.9 29.8 31.7 22.8 19.7 74.6 6.8 17.4 13.7 6.7 15.7 20.9 12.9 2.1 25.7 31.5 19.7 19.6 25.2 1.7 26.5 32.9 20.3 7.2 37.5 4.5 21.4 41.0 16.5 29.0 29.4 19.6 28.1 15.4 11.8 24.3 18.5 4.6 17.0 14.2 12.9 11.5 1.7 13.7 16.8 16.0 4.7 24.2 13.8 37.0 4.0 5.0 35.2 16.0 13.5 25.7 40.0 12.4 15.9 21.6 9.1 6.6 13.7 22.3 30.8 44.9 57.0 34.4 20.8 29.7 22.8 22.4 24.2 CCDC151 "MGC20983, ODA10" ENSG00000198003 "Coiled-coil domain containing 151" A5D8V7 19 11420604-11435782 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.0;parathyroid gland: 9.8;testis: 10.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Kupffer cells: 51.6;Muller glia cells: 58.9;Respiratory ciliated cells: 29.6;Spermatocytes: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.0;T-47d: 4.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA054626 Enhanced NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 5: Muller glia cells - Visual perception" "HPA054626: AB_2682547" "unprognostic (1.50e-1)" "unprognostic (6.59e-2)" "unprognostic (2.05e-3)" "unprognostic (4.41e-3)" "unprognostic (1.35e-2)" "unprognostic (6.30e-2)" "unprognostic (4.41e-3)" "unprognostic (2.32e-2)" "unprognostic (2.22e-1)" "unprognostic (5.09e-2)" "unprognostic (6.76e-4)" "unprognostic (3.01e-1)" "unprognostic (2.63e-3)" "unprognostic (4.27e-2)" "unprognostic (1.85e-1)" "unprognostic (2.35e-1)" "unprognostic (2.05e-1)" 0.4 2.8 4.6 0.0 4.6 0.0 0.4 4.7 6.5 1.6 15.0 0.3 0.0 0.6 0.3 0.2 8.5 0.0 1.9 5.0 4.7 3.5 0.7 2.3 0.0 6.4 6.8 0.6 0.4 9.8 7.0 0.4 5.7 0.8 0.0 0.9 1.7 0.5 0.1 0.5 0.2 0.0 5.2 2.6 0.4 10.4 4.6 0.0 2.9 0.0 0.0 0.3 0.8 4.9 0.2 0.0 0.6 0.2 0.1 0.2 0.5 0.2 0.1 0.3 0.4 0.0 0.0 0.1 0.2 0.1 1.2 0.1 0.5 0.2 0.0 0.5 0.5 0.2 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.5 0.1 0.4 0.0 0.1 0.2 0.1 1.0 0.2 0.0 0.7 0.3 0.0 2.0 1.3 0.6 0.1 0.1 0.1 4.8 0.2 0.0 0.8 0.1 1.7 0.0 1.7 1.4 0.1 1.8 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.6 4.6 4.7 6.5 5.0 4.7 6.4 6.8 5.7 5.2 4.6 4.9 1.1 0.0 0.0 6.5 5.7 0.9 0.7 1.0 0.6 1.1 0.8 1.3 2.2 1.5 2.6 12.9 0.0 0.5 0.0 0.0 29.4 0.2 12.4 20.3 4.2 2.9 0.0 0.0 2.3 0.2 0.5 3.8 0.5 1.1 4.5 1.6 14.3 1.2 4.7 1.7 1.7 0.5 2.0 51.6 1.7 14.5 2.8 7.8 7.2 1.0 2.6 58.9 0.0 1.0 0.8 0.1 0.0 0.7 0.8 0.1 0.1 1.1 29.6 3.2 6.6 15.2 6.8 22.7 6.6 0.1 0.4 1.2 1.5 1.0 0.0 0.5 CCDC160 ENSG00000203952 "Coiled-coil domain containing 160" A6NGH7 X 134237047-134246207 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 45.0;Early spermatids: 14.8;Endometrial ciliated cells: 28.1;Respiratory ciliated cells: 36.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 29.7;RPTEC TERT1: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (7.45e-3)" "unprognostic (2.79e-2)" "prognostic favorable (2.31e-4)" "unprognostic (1.98e-1)" "unprognostic (5.11e-4)" "unprognostic (4.22e-2)" "unprognostic (2.07e-2)" "prognostic favorable (7.62e-6)" "unprognostic (3.32e-2)" "unprognostic (4.51e-2)" "prognostic favorable (2.21e-4)" "unprognostic (5.23e-2)" "unprognostic (1.41e-1)" "unprognostic (2.75e-1)" "unprognostic (2.44e-3)" 0.2 0.0 2.2 0.1 2.2 0.2 3.9 2.8 2.7 2.9 3.9 0.2 0.0 0.7 1.7 0.4 3.3 1.1 0.1 2.2 2.4 6.0 0.0 0.4 0.5 2.5 2.5 1.3 0.5 5.1 0.6 0.2 2.7 1.8 0.1 1.0 16.5 2.6 1.0 0.3 0.0 0.0 2.1 0.4 1.0 2.0 2.3 0.0 0.2 0.0 0.1 0.5 0.3 2.6 0.0 0.0 29.7 2.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 4.1 0.0 0.0 0.0 0.1 0.0 8.3 2.4 0.0 0.1 0.0 0.3 0.4 2.9 3.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.2 2.8 2.7 2.2 2.4 2.5 2.5 2.7 2.1 2.3 2.6 0.2 0.0 0.0 5.5 0.0 0.0 1.0 9.3 0.6 0.3 9.6 9.0 0.5 1.5 10.2 9.2 0.0 0.0 0.0 0.0 45.0 3.2 14.8 28.1 0.5 0.3 0.0 0.0 0.4 0.0 0.3 0.8 0.0 2.5 0.0 0.8 0.4 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 2.9 0.6 0.1 1.8 1.0 0.0 6.9 0.0 6.0 5.6 0.2 0.0 0.4 0.0 1.8 0.0 7.7 36.0 0.6 0.0 0.7 0.6 6.7 10.1 2.3 0.0 0.0 0.1 0.1 0.0 1.4 CCDC172 "C10orf96, MGC35062" ENSG00000182645 "Coiled-coil domain containing 172" P0C7W6 10 116324448-116380029 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "retina: 3.1;testis: 12.2" "Cell type enhanced" "Detected in some" "Early spermatids: 32.9;Late spermatids: 9.6;Spermatocytes: 107.9;Spermatogonia: 22.9" "Cancer enriched" "Detected in single" 14 "testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "NTERA-2: 31.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (9.85e-2)" 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 12.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 31.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.3 0.2 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.6 0.9 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 107.9 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC24 MGC45441 ENSG00000159214 "Coiled-coil domain containing 24" Q8N4L8 1 43991359-43996528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 36.4;Respiratory ciliated cells: 57.6;Spermatocytes: 50.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 1.0;intermediate monocyte: 2.2;memory B-cell: 3.5;naive B-cell: 2.2;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 5 "B-cells: 3.5;granulocytes: 1.0;monocytes: 2.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA035424, HPA061710" Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Nucleoli, Cytosol" "HPA035424: AB_2674619, HPA061710: AB_2684591" "prognostic favorable (3.06e-5)" "unprognostic (1.47e-1)" "unprognostic (1.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.65e-2)" "prognostic favorable (3.18e-4)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.92e-2)" "unprognostic (6.38e-2)" "unprognostic (2.81e-1)" "unprognostic (7.00e-3)" "unprognostic (3.00e-1)" "unprognostic (1.74e-2)" "unprognostic (6.91e-2)" "unprognostic (1.51e-1)" "unprognostic (7.84e-2)" "unprognostic (2.15e-3)" 1.6 4.8 11.8 1.3 11.9 0.4 3.3 11.3 15.9 5.9 12.3 3.8 1.9 3.2 1.9 2.1 11.2 3.1 1.3 11.8 12.0 11.8 3.6 2.9 1.4 11.6 11.8 2.4 5.6 6.2 12.9 1.0 11.7 7.2 2.1 6.6 4.4 5.0 0.8 1.1 2.4 1.3 11.8 2.4 3.8 19.1 12.3 0.9 9.1 0.2 1.0 4.1 2.4 11.5 4.7 2.8 1.2 1.4 1.2 0.8 2.7 0.2 1.9 1.4 2.4 1.8 13.4 3.8 5.0 0.5 4.0 4.7 0.7 6.5 1.3 3.9 1.6 1.9 1.7 0.5 1.3 0.6 3.2 0.3 0.6 4.5 0.4 4.3 1.1 1.4 0.8 1.4 2.0 4.0 0.2 1.4 2.7 4.2 2.2 1.3 0.0 0.7 5.5 1.8 2.9 2.6 4.0 2.3 2.6 2.5 6.7 0.1 0.3 2.1 5.9 1.5 0.7 0.5 1.8 0.8 5.3 0.5 1.7 0.0 0.4 1.0 0.3 2.2 0.2 3.5 0.1 0.1 0.4 2.2 0.0 0.0 0.4 0.3 1.8 0.3 0.0 0.2 11.8 11.9 11.3 15.9 11.8 12.0 11.6 11.8 11.7 11.8 12.3 11.5 1.7 3.2 7.2 17.0 2.3 1.1 7.9 26.5 9.1 8.9 13.3 12.1 1.0 12.8 22.0 9.2 6.2 5.6 0.9 11.3 21.5 9.4 20.7 30.9 2.4 2.1 36.4 1.3 17.7 7.2 2.2 2.5 21.9 6.9 2.5 1.6 2.5 2.6 3.3 3.3 10.0 13.6 14.2 2.0 2.2 11.7 2.1 3.6 3.6 1.9 2.7 10.2 0.0 5.0 2.4 6.5 8.3 3.0 1.8 5.7 6.3 11.5 57.6 15.4 0.0 2.9 3.8 50.6 19.9 3.9 0.9 2.5 1.3 3.9 10.2 11.4 CCDC50 "C3orf6, DFNA44, Ymer" ENSG00000152492 "Coiled-coil domain containing 50" Q8IVM0 3 191329085-191398659 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 363.7;Oligodendrocyte precursor cells: 365.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 630.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 630.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001336 Approved Supported Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA001336: AB_1078421" "unprognostic (5.01e-2)" "unprognostic (1.44e-1)" "unprognostic (7.84e-2)" "unprognostic (8.77e-3)" "unprognostic (1.73e-2)" "unprognostic (8.29e-2)" "prognostic unfavorable (2.48e-5)" "unprognostic (3.03e-2)" "unprognostic (2.51e-2)" "unprognostic (4.48e-2)" "unprognostic (3.17e-3)" "unprognostic (2.05e-2)" "unprognostic (7.79e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-2)" "unprognostic (7.57e-2)" "unprognostic (4.19e-1)" 63.2 28.3 19.6 34.3 20.7 10.3 30.6 21.5 19.1 24.1 18.8 26.9 24.2 33.0 24.8 27.9 24.3 34.8 39.7 17.6 23.3 32.4 56.5 31.6 42.2 24.1 22.0 46.2 35.1 27.6 13.5 34.9 24.1 26.2 25.4 11.8 23.7 33.3 19.0 18.4 25.8 48.1 23.2 45.0 24.3 29.6 21.3 17.7 27.4 26.1 41.0 36.7 18.6 24.7 74.9 24.5 93.6 24.7 82.3 72.1 32.3 135.4 135.2 95.4 95.0 52.6 28.9 14.6 163.0 76.8 70.6 83.6 75.6 60.5 141.9 109.0 37.8 10.0 31.7 60.3 120.8 36.8 37.8 58.2 79.3 75.6 169.7 82.2 148.7 0.0 33.9 77.3 85.4 26.0 0.2 23.1 33.2 7.6 103.0 56.3 51.9 73.1 104.3 31.9 21.8 33.2 48.2 51.6 95.8 67.3 35.6 32.9 153.3 93.4 78.4 68.4 176.3 118.6 54.9 0.9 50.5 0.1 76.9 0.1 22.1 2.1 5.9 20.8 2.4 128.5 6.1 3.9 44.3 76.5 1.3 1.5 2.2 24.0 12.1 630.7 22.1 18.0 19.6 20.7 21.5 19.1 17.6 23.3 24.1 22.0 24.1 23.2 21.3 24.7 143.5 25.6 54.5 40.5 134.5 46.9 52.5 30.7 30.7 27.2 32.5 37.5 48.4 58.6 34.7 51.5 27.1 28.1 363.7 44.1 31.3 120.4 183.0 97.3 58.1 134.0 22.8 11.2 15.8 78.5 36.3 66.6 41.8 79.0 2.5 58.5 175.6 79.5 84.4 25.2 41.3 33.8 38.7 59.4 78.3 92.1 69.3 61.4 53.4 98.4 101.4 32.1 5.2 365.4 28.9 174.7 33.9 75.6 102.7 69.8 37.6 71.8 26.3 14.4 59.2 74.1 65.7 73.2 26.6 24.0 32.5 33.5 22.4 49.5 33.7 62.4 CCDC6 "D10S170, H4, PTC, TPC, TST1" ENSG00000108091 "Coiled-coil domain containing 6" Q16204 10 59788747-59906556 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019049, HPA019051" Enhanced Supported Cytosol No No 12000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" Cytosol "HPA019049: AB_1846163, HPA019051: AB_1846164" "unprognostic (1.88e-2)" "unprognostic (1.72e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-3)" "unprognostic (5.98e-3)" "prognostic favorable (5.48e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (7.39e-2)" "unprognostic (2.45e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.95e-4)" "unprognostic (4.08e-1)" "unprognostic (4.69e-2)" "unprognostic (2.23e-1)" "unprognostic (2.56e-1)" "unprognostic (9.95e-2)" "unprognostic (4.19e-2)" 11.9 12.2 21.1 13.9 23.4 16.8 22.4 10.2 20.0 23.4 8.5 23.5 22.8 24.9 16.7 34.1 25.3 16.7 10.0 24.9 21.4 21.2 12.1 17.3 21.4 12.4 15.8 15.7 25.2 17.9 11.5 13.2 17.4 19.4 19.8 18.3 29.0 14.3 17.3 28.6 16.2 30.8 11.9 14.7 18.6 11.4 20.8 12.1 18.3 12.2 21.6 17.3 23.1 12.6 42.9 38.0 18.7 41.9 27.8 41.6 37.9 20.6 27.2 20.2 23.7 74.4 81.8 36.5 30.2 34.6 11.7 61.7 37.7 37.5 30.0 55.1 18.7 29.8 29.1 45.5 33.5 34.5 26.9 30.3 48.7 33.7 81.8 28.3 30.2 20.4 22.6 22.7 26.6 57.6 14.5 19.8 29.9 40.1 25.6 19.2 30.5 23.0 33.9 36.2 19.0 16.6 26.1 107.8 23.1 24.1 68.7 18.4 31.1 18.8 33.9 29.3 34.9 12.0 14.9 16.3 29.6 64.6 11.9 0.0 2.0 0.0 1.0 2.3 1.1 4.3 1.5 1.3 5.0 4.9 1.3 1.0 0.1 0.8 1.3 1.3 1.4 1.0 21.1 23.4 10.2 20.0 24.9 21.4 12.4 15.8 17.4 11.9 20.8 12.6 24.0 99.3 25.9 45.1 41.6 95.0 51.7 25.3 70.0 15.1 51.2 38.7 16.5 28.6 46.3 25.8 41.7 37.8 31.4 42.6 29.4 50.2 27.6 105.2 54.6 22.4 27.0 25.7 83.2 65.3 18.8 27.8 39.8 134.5 29.1 45.2 17.2 20.1 23.1 16.8 58.4 38.9 30.5 40.7 35.3 80.6 24.5 36.4 16.0 32.8 23.0 11.5 13.4 55.3 34.2 50.2 25.0 19.5 26.4 52.2 47.1 48.4 28.1 49.8 19.7 31.4 27.0 2.3 22.4 92.3 80.1 27.0 24.3 32.5 46.3 46.1 CCDC68 SE57-1 ENSG00000166510 "Coiled-coil domain containing 68" Q9H2F9 18 54901509-54959461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.8;placenta: 32.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 95.2;Early spermatids: 95.4;Pancreatic endocrine cells: 87.9;Paneth cells: 68.7;Proximal enterocytes: 61.1" "Cancer enhanced" "Detected in many" "stomach cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 10.8;HHSteC: 13.6;HSkMC: 14.9;RT4: 10.5;TIME: 28.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA040865, HPA048197" Supported Approved "Golgi apparatus,Cytosol" No NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Cytosol "HPA040865: AB_2677176, HPA048197: AB_2680310" "unprognostic (1.36e-2)" "prognostic unfavorable (4.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.38e-2)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (2.65e-2)" "unprognostic (6.29e-2)" "unprognostic (2.71e-1)" "unprognostic (1.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.77e-2)" "unprognostic (9.71e-2)" "unprognostic (6.12e-2)" "unprognostic (2.38e-1)" 5.5 3.8 1.6 4.1 1.5 0.4 3.4 1.4 2.7 4.2 2.3 18.9 20.2 3.3 0.8 1.8 2.4 5.1 5.7 1.5 3.6 2.8 9.5 13.0 0.8 2.0 2.3 15.7 2.8 0.8 3.6 32.4 2.0 4.2 18.2 0.6 1.8 1.3 1.5 0.9 24.8 2.7 1.2 7.2 14.3 8.8 3.3 0.6 2.6 4.4 1.3 2.3 1.8 1.3 10.8 3.3 0.0 0.0 3.0 8.3 0.0 0.3 4.2 0.6 0.7 5.9 6.2 0.0 7.6 0.0 0.1 0.1 0.7 6.8 0.5 0.0 1.6 0.8 3.6 1.2 13.6 0.0 0.0 14.9 0.0 3.2 0.1 0.0 4.9 0.0 0.0 0.1 0.4 0.8 0.0 0.2 0.0 7.6 3.6 0.3 0.0 0.3 1.2 10.5 0.1 2.5 3.3 1.0 0.1 1.2 0.0 0.0 28.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.6 1.5 1.4 2.7 1.5 3.6 2.0 2.3 2.0 1.2 3.3 1.3 38.5 19.2 10.3 0.3 1.0 0.3 7.4 4.8 1.2 0.1 2.0 1.9 5.5 10.0 13.3 1.8 0.0 2.3 0.3 95.2 1.9 7.2 95.4 15.0 2.5 40.8 6.0 3.6 5.7 35.6 2.7 9.6 38.2 27.1 8.8 2.6 37.5 7.0 0.4 0.0 0.5 21.8 8.2 3.2 1.3 36.7 3.4 0.6 0.0 12.2 1.0 3.3 1.0 0.0 0.1 87.9 68.7 0.7 0.0 32.4 61.1 5.3 4.2 0.2 6.6 0.9 3.0 1.2 2.2 1.1 0.0 6.0 0.4 3.8 20.2 6.4 CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 351.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;dendritic cells: 106.9;Granulosa cells: 138.2;NK-cells: 197.8;Plasma cells: 133.6;Theca cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 129.2;Daudi: 199.9;U-266/70: 120.5;U-698: 119.1" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 108.9 89.6 6.7 45.8 8.4 46.3 60.5 12.2 7.9 15.2 13.4 138.5 19.6 32.9 13.3 54.1 37.1 19.3 96.9 5.9 8.9 10.7 24.0 39.0 70.4 13.3 13.8 27.1 47.5 32.1 8.5 14.8 13.6 23.0 20.5 1.8 14.4 29.4 351.9 13.3 44.7 45.6 11.3 55.4 37.0 13.2 9.2 37.8 11.6 163.8 66.8 87.7 21.9 7.2 8.0 1.6 0.4 6.4 129.2 13.1 4.2 1.5 13.1 2.6 2.4 2.1 1.1 199.9 6.3 0.5 3.3 1.0 3.0 2.8 0.9 0.1 2.7 27.0 0.0 17.5 21.1 9.9 34.4 33.0 0.2 1.0 0.0 2.5 13.1 0.0 23.7 44.0 0.1 0.6 43.8 23.3 7.5 0.1 15.2 36.0 1.0 12.1 0.5 5.9 0.2 0.8 2.4 3.2 1.7 3.2 2.0 24.0 32.0 1.0 6.1 0.6 1.5 120.5 60.1 119.1 1.4 22.2 0.0 30.9 12.4 13.5 11.3 10.9 10.3 5.4 8.8 10.8 10.0 10.4 6.1 6.6 9.6 14.3 10.3 19.3 8.5 11.5 6.7 8.4 12.2 7.9 5.9 8.9 13.3 13.8 13.6 11.3 9.2 7.2 51.0 12.8 78.4 0.7 68.8 2.5 3.0 3.5 1.2 0.4 4.8 2.4 124.5 1.5 13.5 1.8 0.0 7.3 106.9 0.2 0.0 2.9 0.5 26.8 2.7 58.9 1.8 32.2 1.8 20.0 9.6 18.4 7.1 1.3 34.8 138.2 28.2 39.7 7.3 6.7 2.7 0.0 4.1 64.0 12.2 2.4 5.6 46.5 10.6 11.2 73.5 4.9 197.8 1.0 0.6 8.8 0.1 7.9 133.6 3.6 4.5 3.2 51.3 1.4 13.1 4.7 14.8 1.2 1.0 0.7 1.3 35.4 65.7 132.1 0.9 23.5 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCDC96 FLJ90575 ENSG00000173013 "Coiled-coil domain containing 96" Q2M329 4 7040849-7043001 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 65.4" "Cell type enhanced" "Detected in many" "Early spermatids: 76.7;Endometrial ciliated cells: 59.7;Late spermatids: 93.4;Respiratory ciliated cells: 53.4;Spermatocytes: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 5.3" HPA047546 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA047546: AB_2680082" "unprognostic (6.20e-3)" "unprognostic (4.03e-2)" "unprognostic (7.95e-2)" "prognostic favorable (4.05e-4)" "unprognostic (1.22e-2)" "unprognostic (3.51e-3)" "unprognostic (1.77e-1)" "unprognostic (9.24e-3)" "unprognostic (1.01e-2)" "unprognostic (3.92e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.43e-1)" "prognostic favorable (3.80e-5)" "unprognostic (4.37e-2)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (1.10e-2)" 0.8 2.0 2.0 0.5 2.4 1.3 1.2 2.4 2.1 1.1 6.0 0.8 0.9 0.8 0.7 1.3 10.7 0.8 0.6 2.5 2.1 1.4 0.5 1.7 0.8 3.4 3.7 0.7 1.3 1.0 3.3 0.5 3.0 1.0 0.6 1.8 1.0 1.1 1.1 1.7 0.8 0.6 2.7 0.8 1.1 65.4 2.6 0.7 1.5 0.7 0.6 0.7 0.9 1.9 1.0 2.7 1.4 1.1 1.8 1.2 0.3 2.7 1.6 3.0 1.8 0.9 2.4 0.6 0.7 1.5 3.9 1.2 0.5 1.2 0.9 0.1 0.4 0.6 1.1 0.7 0.9 0.8 1.5 1.1 1.3 1.8 0.2 0.3 1.2 1.9 0.4 0.2 1.9 2.4 1.6 1.0 0.5 0.9 1.6 0.6 0.9 0.1 5.3 1.0 3.8 0.8 2.2 1.0 0.5 1.3 1.0 1.5 1.3 2.5 0.7 1.5 2.1 0.0 0.1 0.5 1.9 0.0 0.8 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.1 0.0 0.5 0.0 0.0 0.5 0.1 0.1 1.0 0.0 0.0 0.1 2.0 2.4 2.4 2.1 2.5 2.1 3.4 3.7 3.0 2.7 2.6 1.9 3.1 0.0 4.8 0.0 1.0 0.6 0.8 2.8 0.6 4.0 3.7 3.2 0.9 0.0 6.9 3.7 12.5 0.6 0.7 2.5 1.9 2.2 76.7 59.7 4.0 2.3 5.4 0.0 0.0 1.1 0.6 1.5 0.5 2.4 0.0 0.6 2.9 0.9 1.2 0.0 0.0 1.9 4.1 2.2 0.9 93.4 3.1 1.7 1.8 0.0 1.1 6.9 0.0 0.0 0.0 1.7 2.7 4.1 0.1 1.2 0.2 4.5 53.4 19.6 0.0 4.6 2.3 30.6 3.6 1.2 1.0 0.5 0.8 2.7 0.8 0.9 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCL17 "ABCD-2, SCYA17, TARC" ENSG00000102970 "C-C motif chemokine ligand 17" Q92583 16 57404767-57416063 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 21.1" "Cell type enriched" "Detected in some" 55 "monocytes: 12161.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 640 "HDLM-2: 2395.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "basal ganglia: 4.3" CAB002583 Uncertain "Secreted to blood" NA NA 248000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB002583: AB_564022" "unprognostic (4.62e-3)" "prognostic favorable (1.91e-5)" "unprognostic (5.83e-2)" "unprognostic (3.52e-4)" "unprognostic (4.51e-2)" "unprognostic (1.78e-3)" "unprognostic (4.44e-1)" "unprognostic (3.41e-2)" "unprognostic (6.36e-2)" "unprognostic (4.28e-2)" "unprognostic (4.11e-1)" "unprognostic (2.91e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-1)" "unprognostic (7.72e-3)" "unprognostic (4.14e-3)" "prognostic favorable (5.80e-4)" 1.2 0.1 0.1 8.3 0.1 0.0 1.9 0.1 0.4 1.4 0.0 1.5 0.1 0.0 0.0 3.1 0.6 2.9 1.3 0.2 0.0 0.6 0.3 4.5 8.4 0.1 0.0 0.2 0.5 0.1 0.0 0.1 0.1 0.3 2.7 0.0 2.5 0.2 0.1 2.4 3.7 2.6 0.0 0.8 0.7 0.5 0.1 21.1 0.8 0.2 5.7 3.4 0.9 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 3.3 0.0 0.0 0.0 2395.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.0 3.7 0.2 0.0 0.0 2.9 1.5 0.1 0.1 2.0 0.0 0.0 0.1 0.0 1.0 0.0 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.0 5.1 0.0 0.4 10.8 0.1 3.4 0.0 0.0 1.1 1.5 0.0 0.0 3.8 0.0 0.0 0.0 0.3 0.0 0.0 4.2 0.3 0.1 0.0 0.6 0.0 0.0 0.2 37.4 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 2.0 1.0 217.9 0.3 0.0 48.7 0.0 0.0 12161.5 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.1 0.0 0.4 2.1 0.0 0.0 0.0 12.0 0.0 0.5 0.0 2.7 0.0 0.4 0.0 0.0 0.7 CCL27 "ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine" ENSG00000213927 "C-C motif chemokine ligand 27" Q9Y4X3 9 34661880-34664048 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 485.0" "Group enriched" "Detected in some" 26 "Basal keratinocytes: 704.5;Suprabasal keratinocytes: 1004.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.9" "Not detected" "Not detected" HPA073848 Enhanced "Secreted to blood" NA NA 436000 1800000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 61: Skin - Cornification" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" "HPA073848: AB_2732243" 0.3 0.0 1.8 0.1 1.8 1.6 27.6 3.5 4.8 0.6 1.5 0.1 0.3 0.7 3.1 0.7 0.2 0.7 0.6 1.8 1.8 0.0 0.3 0.1 0.3 2.0 1.8 0.9 0.1 0.1 0.1 0.3 1.9 0.2 0.2 0.9 0.3 0.1 1.4 485.0 0.1 0.2 1.9 0.1 0.1 1.3 1.8 4.6 1.2 0.3 0.2 0.1 0.6 2.2 0.0 0.0 0.3 1.9 0.8 0.3 0.2 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 1.1 0.7 0.0 0.0 1.1 0.4 0.3 0.0 0.0 1.4 0.8 0.2 0.0 0.3 0.0 0.5 0.2 1.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 1.2 0.0 0.1 0.5 0.0 0.0 0.1 1.3 0.7 0.0 0.0 0.9 0.8 0.7 0.0 0.1 0.1 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 1.8 3.5 4.8 1.8 1.8 2.0 1.8 1.9 1.9 1.8 2.2 0.1 0.0 0.0 0.3 0.0 704.5 0.3 0.3 0.0 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 7.8 0.0 0.3 1.7 0.0 0.0 0.2 0.2 0.8 2.3 0.0 0.1 0.0 0.1 0.4 0.1 0.2 0.0 0.1 0.2 0.0 0.0 28.4 9.6 0.3 0.0 32.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.6 0.5 0.0 0.2 0.0 0.2 1.6 4.5 1.5 0.0 1004.0 1.9 0.8 0.0 0.2 0.1 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 8 "dendritic cells: 2049.9;NK-cells: 2344.0;T-cells: 1947.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Cell line enhanced" "Detected in some" "HL-60: 94.1;NB-4: 539.9;THP-1: 139.9;U-937: 120.1" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 17.2 17.1 3.9 36.3 4.0 122.1 19.5 3.8 6.5 15.5 5.4 27.7 48.7 15.7 14.4 15.8 14.0 42.9 8.9 3.9 3.7 7.5 28.4 57.4 135.2 7.3 4.3 16.9 7.0 3.0 3.8 6.3 6.4 10.4 25.6 0.3 33.5 7.9 4.8 4.0 84.5 10.5 5.8 123.9 47.9 4.6 4.7 29.5 11.5 2.7 33.4 31.4 9.5 6.1 0.7 0.5 0.2 0.0 0.5 0.4 0.8 0.3 4.0 17.8 20.8 0.4 1.7 0.3 1.6 0.9 1.3 0.9 0.0 0.0 2.3 6.5 0.3 0.0 1.5 0.6 0.5 94.1 0.8 0.1 0.2 5.5 0.3 0.0 0.2 0.1 0.1 12.5 0.2 0.6 0.1 539.9 0.5 0.0 0.0 0.6 0.2 14.0 0.2 0.5 0.1 0.5 0.2 1.2 13.4 0.5 0.2 139.9 0.3 0.6 0.3 0.6 0.4 14.2 6.6 0.8 0.4 120.1 1.3 657.8 30.0 35.8 6788.6 21.3 4221.0 61.3 1394.5 7164.3 49.8 41.6 332.4 4032.4 189.9 2041.1 26.1 46.5 25.9 6664.4 3.9 4.0 3.8 6.5 3.9 3.7 7.3 4.3 6.4 5.8 4.7 6.1 22.4 99.3 244.4 0.3 55.2 7.4 1.3 6.0 4.6 1.3 19.9 18.2 5.4 21.5 41.7 1.8 0.0 1.8 2049.9 3.1 1.9 6.3 1.2 5.5 5.4 24.2 1.8 106.3 0.5 0.2 7.1 26.0 46.9 6.7 80.8 0.2 45.0 7.0 33.8 0.0 0.3 3.5 0.0 48.0 25.0 0.1 0.3 256.3 12.4 2.8 38.5 0.4 2344.0 0.0 0.4 1.6 6.9 0.4 179.5 1.7 2.4 6.7 29.2 1.1 0.0 6.5 28.2 1.1 1.2 5.5 6.3 16.0 1947.0 0.1 3.5 1.9 CCM2L "C20orf160, dJ310O13.5" ENSG00000101331 "CCM2 like scaffold protein" Q9NUG4 20 32010438-32032180 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 141.6" "Cell type enriched" "Detected in some" 5 "Theca cells: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.2;HUVEC TERT2: 9.0;NTERA-2: 4.6;RH-30: 3.2;SCLC-21H: 7.7;TIME: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008434, HPA071063" Uncertain Supported Nucleoplasm NA NA "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA008434: AB_1845671, HPA071063: AB_2686339" "unprognostic (1.71e-1)" "unprognostic (4.64e-2)" "unprognostic (2.43e-3)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (1.27e-3)" "unprognostic (2.37e-1)" "unprognostic (2.04e-1)" "unprognostic (4.34e-2)" "unprognostic (1.00e-3)" "unprognostic (7.84e-2)" "unprognostic (4.66e-3)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" 15.9 5.4 7.2 1.6 7.3 0.0 15.0 9.5 6.8 8.7 4.2 4.6 1.3 8.9 0.6 3.7 7.7 2.5 23.2 6.1 5.8 13.3 2.2 11.8 1.5 6.8 6.4 3.6 2.6 1.4 4.1 7.8 7.0 5.8 1.1 0.4 3.4 1.8 4.8 3.9 5.4 3.3 6.1 141.6 4.2 1.6 7.3 0.8 10.2 4.8 0.9 6.4 6.3 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 9.0 0.9 0.0 0.0 0.0 2.4 0.0 0.0 4.6 0.1 0.0 0.6 3.2 0.1 0.0 0.0 7.7 0.9 0.2 0.0 0.0 1.1 2.5 0.0 4.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 7.3 9.5 6.8 6.1 5.8 6.8 6.4 7.0 6.1 7.3 5.2 45.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.5 0.6 4.6 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.2 32.1 0.0 0.0 2.9 0.2 0.0 1.0 0.0 0.2 0.0 4.3 24.3 0.0 0.0 3.3 2.4 0.0 0.0 0.3 0.3 0.4 0.0 0.2 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 1.8 0.3 0.6 0.1 0.3 0.0 0.1 248.7 0.0 0.1 CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.6;lymphoid tissue: 46.9;retina: 31.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Erythroid cells: 102.1;Extravillous trophoblasts: 92.8;Plasma cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB000114: AB_563675, HPA020626: AB_1847376" "unprognostic (4.02e-2)" "unprognostic (1.93e-1)" "unprognostic (7.66e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.25e-1)" "unprognostic (1.67e-2)" "prognostic unfavorable (9.17e-5)" "prognostic unfavorable (4.27e-4)" "unprognostic (3.92e-3)" "unprognostic (2.65e-2)" "prognostic unfavorable (4.43e-6)" "unprognostic (8.38e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (6.07e-2)" "unprognostic (1.59e-1)" 1.5 1.2 2.5 11.4 2.5 38.6 2.5 3.5 4.7 4.3 2.5 9.8 10.1 2.5 0.6 8.4 2.2 1.8 1.3 2.3 2.4 1.5 1.6 1.8 25.0 2.8 2.7 3.8 0.8 0.6 2.7 10.5 2.6 1.9 11.5 31.7 1.8 0.8 0.7 6.7 9.9 4.0 2.6 4.6 4.4 6.2 2.6 46.9 1.2 0.5 24.4 2.9 3.9 3.5 177.1 45.3 120.5 51.8 6.4 16.3 98.8 119.7 52.8 156.7 115.6 99.4 106.5 161.2 31.7 63.8 55.0 58.0 154.2 71.1 128.0 77.8 70.8 129.7 56.0 96.9 1.5 197.0 88.0 4.2 5.3 65.1 38.7 24.7 95.4 84.3 187.9 156.9 126.1 63.8 251.8 113.1 95.5 109.9 49.8 114.1 233.5 78.2 44.8 34.6 51.0 53.8 63.1 76.0 32.4 89.8 63.7 81.9 56.5 72.7 109.3 77.4 115.9 98.0 112.3 181.9 41.5 197.6 82.4 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.9 0.6 0.4 0.0 0.0 0.2 0.1 0.8 0.1 0.0 3.1 0.9 2.5 2.5 3.5 4.7 2.3 2.4 2.8 2.7 2.6 2.6 2.6 3.5 0.8 0.0 1.1 1.6 5.7 2.8 1.5 5.5 1.8 2.9 1.9 1.8 0.8 0.0 1.6 0.0 12.5 47.9 1.9 4.9 0.0 0.7 9.6 0.6 2.7 3.3 1.2 102.1 3.3 0.2 92.8 6.3 9.2 2.1 0.0 18.1 4.2 0.9 25.3 0.0 4.1 7.7 8.2 6.9 3.6 2.1 0.9 3.6 1.8 2.8 0.2 1.2 0.0 4.5 5.2 0.5 3.1 1.2 35.5 3.3 1.8 0.2 2.5 14.2 0.0 0.9 6.0 10.3 17.7 24.0 1.3 8.5 6.3 1.4 19.9 2.1 CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.9;lymphoid tissue: 76.2" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 723.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "CAB000115: , CAB003804: AB_562272, HPA030741: AB_2673586, HPA061448: AB_2684522" "unprognostic (4.12e-2)" "unprognostic (2.75e-2)" "unprognostic (1.91e-3)" "unprognostic (4.08e-3)" "unprognostic (2.78e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.54e-7)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.43e-2)" "unprognostic (1.63e-2)" "unprognostic (2.49e-3)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.44e-1)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (5.15e-3)" 4.0 5.1 4.0 26.0 3.9 52.9 10.0 6.0 4.9 6.3 2.8 22.2 20.9 7.7 5.4 36.0 8.2 4.0 3.0 3.8 4.0 4.8 4.3 3.9 54.5 6.2 4.4 5.0 4.2 5.8 2.6 20.8 6.5 3.8 29.5 5.7 6.5 3.9 3.4 14.5 19.5 14.4 3.5 11.1 10.8 32.9 5.2 76.2 9.3 2.0 67.0 8.4 10.4 4.0 466.0 317.1 423.5 377.1 22.2 37.1 980.2 201.3 150.8 521.3 437.0 471.2 423.9 285.2 239.1 187.6 594.2 284.2 432.4 442.8 577.2 281.4 217.2 181.6 243.2 323.2 6.8 160.5 197.7 16.6 27.7 300.5 207.2 47.7 282.8 274.2 223.5 217.9 430.2 441.4 220.5 184.7 236.7 153.3 199.3 228.4 305.2 288.2 192.6 168.2 212.7 133.5 347.7 160.3 141.9 236.4 306.4 162.5 119.8 114.4 368.5 207.6 510.2 109.2 216.6 399.8 158.8 271.9 358.6 3.1 2.0 1.5 3.2 5.1 4.5 15.4 8.3 7.4 6.0 11.1 2.7 2.6 1.3 8.2 2.4 5.0 17.6 6.2 4.0 3.9 6.0 4.9 3.8 4.0 6.2 4.4 6.5 3.5 5.2 4.0 4.0 0.0 0.5 2.0 11.8 11.5 7.2 32.1 4.6 4.8 9.8 12.3 1.9 1.5 8.8 5.5 2.1 108.2 8.3 9.5 1.9 6.5 110.2 15.2 7.4 6.6 1.2 76.2 2.7 1.4 723.1 18.3 21.4 13.0 2.5 63.0 8.9 3.2 60.2 0.0 2.1 13.8 73.2 12.0 7.2 17.8 3.1 9.7 3.6 1.0 2.7 3.9 2.1 0.5 1.0 2.4 1.5 2.6 24.1 4.5 2.5 5.6 13.1 4.1 6.6 4.9 18.5 74.3 62.2 37.4 7.2 41.5 8.0 11.8 33.4 7.8 CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 74.6;lymphoid tissue: 73.1;testis: 69.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.9;Early spermatids: 228.5;Erythroid cells: 123.6;Extravillous trophoblasts: 128.3;Spermatocytes: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Golgi apparatus" "CAB009575: AB_2072392, HPA008873: AB_1078604" "unprognostic (2.69e-2)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (2.83e-4)" "prognostic unfavorable (4.63e-4)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (4.48e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (3.98e-2)" "unprognostic (4.44e-1)" 1.0 1.1 0.4 12.2 1.1 74.6 2.9 0.7 0.7 2.9 1.1 14.3 14.1 2.6 0.3 16.1 1.1 1.9 0.7 0.6 0.7 1.1 1.4 2.2 33.0 1.3 1.0 0.8 0.7 0.2 0.3 11.4 1.0 1.6 16.8 0.3 2.8 0.4 0.7 9.4 12.0 6.4 0.7 7.1 5.6 69.4 1.1 73.1 1.0 0.4 43.7 3.6 5.6 2.2 132.5 112.1 188.6 47.1 8.5 16.6 97.5 104.8 69.9 165.2 135.6 187.8 81.1 122.1 75.4 71.8 97.2 160.1 181.4 92.6 157.8 124.1 92.4 153.1 127.3 108.1 2.5 118.1 98.6 6.3 12.6 71.4 91.9 32.7 114.1 147.0 163.1 194.5 128.2 96.5 137.9 177.2 138.6 58.5 65.2 157.5 260.0 124.4 53.3 91.9 115.2 75.9 148.9 80.2 97.3 147.9 139.4 120.4 58.5 81.6 134.4 90.5 210.5 84.2 133.2 213.8 53.6 267.1 117.9 0.0 0.1 0.7 0.1 0.0 0.3 2.1 4.6 5.0 3.0 1.7 0.0 0.1 0.8 3.6 0.1 0.1 22.7 2.1 0.4 1.1 0.7 0.7 0.6 0.7 1.3 1.0 1.0 0.7 1.1 2.2 0.3 0.0 0.6 0.0 6.8 4.8 2.8 11.5 1.8 0.2 2.5 3.3 0.5 0.0 3.2 0.0 0.0 67.9 1.6 4.1 0.0 0.7 228.5 5.3 3.1 3.9 3.0 123.6 0.7 0.2 128.3 7.2 7.1 5.9 0.0 29.9 6.1 1.1 29.9 0.0 0.8 10.1 20.3 10.6 3.3 53.5 4.4 7.9 0.0 0.0 2.4 0.2 1.0 0.0 1.4 0.4 1.9 1.9 18.7 2.3 2.1 0.0 1.8 0.3 0.0 1.0 5.7 288.7 32.1 20.3 6.1 16.3 4.4 4.1 23.4 5.0 CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 499.7;Ductal cells: 504.0;Pancreatic endocrine cells: 622.1;Urothelial cells: 412.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/70: 874.2;WM-115: 1239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "CAB000024: AB_563678, HPA027802: AB_2672390" "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" 55.6 29.2 12.1 10.0 14.6 1.5 40.2 15.0 11.9 17.0 33.4 19.8 22.7 14.8 27.6 72.9 30.8 19.5 64.9 10.8 14.6 32.2 107.3 61.1 10.5 17.5 15.5 4.6 86.3 82.7 25.7 63.7 18.3 53.3 17.2 3.2 30.4 50.4 3.6 120.3 16.0 23.3 15.9 37.2 52.7 3.2 21.7 9.9 45.5 5.2 19.0 29.5 43.9 24.0 467.3 183.0 59.5 1.8 178.3 186.7 127.4 717.5 264.9 82.1 47.6 206.9 349.9 0.1 317.6 375.5 137.2 332.1 6.5 195.2 146.0 1.2 36.5 0.3 46.7 211.7 43.3 3.3 6.7 106.5 37.9 116.0 44.0 192.5 142.1 0.2 0.6 1.3 654.2 197.1 0.4 26.6 109.0 190.7 198.3 1.2 187.9 11.3 379.4 282.8 10.0 231.4 9.2 167.7 458.4 143.5 102.6 9.5 600.4 399.5 111.0 176.1 496.2 874.2 559.4 1.5 341.6 5.9 1239.0 0.2 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 1.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.1 14.6 15.0 11.9 10.8 14.6 17.5 15.5 18.3 15.9 21.7 24.0 84.6 182.7 115.6 0.3 8.3 202.5 234.7 499.7 133.1 2.3 163.4 140.0 80.0 92.9 271.6 125.0 2.1 10.9 2.4 44.8 31.3 504.0 0.4 104.2 23.5 141.0 56.5 2.5 0.5 142.6 1.2 67.6 127.4 199.5 29.1 0.0 98.2 165.2 75.0 0.0 2.2 42.6 75.3 18.8 61.9 2.0 4.1 23.6 51.6 17.8 2.4 79.1 0.0 49.8 0.3 622.1 118.0 57.6 0.5 262.0 19.4 57.1 85.9 3.1 131.5 13.0 184.8 0.5 23.4 292.3 351.1 2.5 8.8 3.4 82.2 412.6 CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811991-29824312 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.8;placenta: 30.8" "Cell type enriched" "Detected in many" 14 "Extravillous trophoblasts: 1756.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "BEWO: 293.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm Yes Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB000308: , CAB016682: AB_1614564, HPA018169: AB_1847384" "unprognostic (2.90e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (6.35e-6)" "unprognostic (5.78e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (3.89e-5)" "unprognostic (1.26e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.29e-2)" "unprognostic (7.07e-2)" "unprognostic (1.11e-16)" "unprognostic (5.61e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-2)" "unprognostic (1.46e-1)" 1.2 5.7 1.9 4.3 2.1 35.8 0.8 2.8 2.7 1.0 0.9 3.9 3.0 1.4 0.6 4.4 0.9 1.0 2.3 2.0 2.5 1.0 0.7 1.1 6.1 2.0 2.1 0.8 1.8 2.8 0.9 30.8 2.0 1.0 4.7 2.0 1.5 1.4 2.1 4.1 2.5 2.2 1.7 4.2 2.1 12.1 2.5 4.5 1.6 1.8 7.8 3.0 1.8 2.3 15.6 31.8 24.3 34.0 5.2 6.0 293.1 24.7 5.3 10.8 13.2 33.0 31.2 13.3 55.9 11.1 14.0 4.9 28.8 12.8 15.2 41.9 17.7 11.2 30.0 34.5 4.1 44.0 28.7 6.2 7.1 14.8 1.9 3.4 13.3 13.2 45.6 5.8 16.8 24.4 24.5 13.0 40.1 36.2 7.2 36.2 28.6 10.1 8.4 24.6 20.5 17.4 35.4 42.7 3.9 35.4 9.5 32.7 8.0 25.0 92.8 14.9 16.9 24.1 18.2 91.6 13.8 5.6 13.7 0.0 0.0 0.0 0.1 0.5 0.3 0.6 0.1 0.0 0.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.3 0.1 1.9 2.1 2.8 2.7 2.0 2.5 2.0 2.1 2.0 1.7 2.5 2.3 3.1 0.0 0.6 0.7 4.8 4.8 1.5 0.3 2.2 2.9 8.2 11.3 3.1 0.0 1.4 0.0 0.0 122.4 3.7 3.5 0.0 0.4 14.6 7.5 4.1 1.9 3.0 30.7 2.9 0.7 1756.5 6.0 5.6 20.1 0.0 4.6 1.4 0.2 43.4 3.3 5.1 3.3 0.0 1.0 2.5 3.6 1.2 4.2 1.8 0.0 0.2 1.7 0.0 2.5 1.3 1.4 2.2 2.2 18.4 2.2 1.0 0.4 0.1 1.1 6.6 4.1 3.4 25.0 17.6 8.5 6.0 115.7 4.5 6.9 4.9 3.5 CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060596, HPA070495, HPA071600" Enhanced Supported Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA060596: AB_2684329, HPA070495: AB_2686273, HPA071600: AB_2686424" "unprognostic (3.87e-2)" "unprognostic (2.21e-2)" "unprognostic (1.57e-3)" "unprognostic (3.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (7.46e-7)" "unprognostic (2.45e-2)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (2.74e-1)" 1.4 1.0 2.5 3.8 2.1 7.3 1.9 2.9 2.7 1.3 0.0 2.0 2.8 0.8 2.0 4.0 0.8 0.8 0.6 2.4 2.0 0.6 0.7 1.0 7.4 1.5 2.0 1.0 0.8 0.5 0.8 2.5 1.3 1.6 2.0 0.8 2.1 1.1 1.3 4.8 2.1 1.1 0.8 2.2 1.6 2.7 2.6 15.1 0.7 1.3 9.6 1.7 1.5 1.7 21.0 32.4 31.3 28.9 2.2 2.9 23.8 24.1 12.2 34.2 26.1 64.6 25.6 42.3 8.0 14.1 10.2 33.1 52.2 19.6 16.4 30.9 23.4 46.1 35.3 20.4 2.3 30.4 30.7 2.0 2.5 24.1 11.7 4.4 25.5 36.5 52.0 28.5 17.6 45.6 46.1 25.0 31.2 22.6 13.2 76.2 35.1 39.5 9.5 9.3 29.8 17.0 36.0 32.8 6.4 15.6 34.3 16.6 18.1 19.1 46.7 13.5 27.1 16.4 20.9 74.5 5.6 31.8 26.9 0.0 0.3 0.0 0.7 0.1 0.4 0.6 0.4 0.9 0.1 0.4 0.3 0.4 0.0 1.3 0.3 0.5 0.5 0.6 2.5 2.1 2.9 2.7 2.4 2.0 1.5 2.0 1.3 0.8 2.6 1.7 0.9 0.0 3.9 3.3 2.7 2.8 2.7 1.4 6.2 5.3 2.4 2.0 1.9 0.0 1.6 1.8 12.5 7.0 3.7 2.4 0.0 1.2 0.9 1.0 2.7 2.2 1.2 37.5 5.7 0.6 12.2 2.2 5.6 1.0 1.3 8.9 2.5 0.9 6.1 8.4 5.6 2.6 4.1 2.4 1.6 0.0 1.8 1.5 5.4 0.0 0.8 0.9 2.1 1.0 1.0 1.1 0.3 2.6 7.2 1.9 0.9 0.2 0.3 1.6 0.0 0.8 2.7 3.9 5.7 3.5 1.1 1.9 3.4 1.7 4.7 1.6 CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.5" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 81.2;Hofbauer cells: 117.4;Kupffer cells: 171.9;Macrophages: 74.2;monocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 330.3;RPMI-8226: 158.5;U-266/70: 57.7;U-266/84: 183.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" 21.0 4.7 2.1 42.5 2.3 24.8 4.0 2.4 3.1 2.5 2.6 5.6 7.3 2.5 1.6 3.4 2.8 11.7 2.4 1.9 2.6 4.9 17.2 18.7 10.9 5.2 3.2 2.1 3.1 1.9 0.9 26.4 4.5 1.6 7.3 0.3 2.1 2.6 1.3 0.6 6.6 15.5 4.7 30.8 4.9 1.7 4.9 5.7 1.0 3.3 10.2 16.7 0.7 7.4 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.3 0.7 1.5 0.1 0.4 0.0 3.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 6.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 330.3 0.0 0.2 0.2 13.0 0.0 0.0 0.0 0.1 0.0 158.5 0.0 5.6 0.0 0.0 0.0 0.4 1.3 0.9 0.2 35.5 0.0 0.8 0.0 0.0 0.2 57.7 183.7 0.1 29.1 26.5 0.4 82.5 125.1 25.8 10.5 76.2 50.1 2.9 0.1 8.5 53.9 0.2 0.1 1.4 113.4 84.5 51.3 18.9 0.1 50.6 2.1 2.3 2.4 3.1 1.9 2.6 5.2 3.2 4.5 4.7 4.9 7.4 0.3 3.2 3.0 0.0 2.0 0.9 0.0 0.0 0.6 0.0 0.1 0.5 0.6 0.0 1.3 0.0 0.0 1.3 15.9 0.0 1.9 0.0 0.4 0.1 0.6 1.6 0.0 1.7 0.0 0.0 81.2 2.4 0.0 0.0 3.8 0.0 1.4 1.2 117.4 0.0 0.0 0.0 0.0 171.9 23.5 0.1 0.0 74.2 5.4 9.4 51.5 0.2 7.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 3.2 1.5 0.2 0.0 0.4 0.5 0.0 0.2 0.2 1.7 2.9 6.0 0.0 0.0 0.0 CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951644-32956349 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.0;urinary bladder: 5.4" "Cell type enhanced" "Detected in some" "granulocytes: 2.5;Horizontal cells: 5.0;Plasma cells: 2.1;Spermatogonia: 1.8;T-cells: 7.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "T-reg: 60.9" "Lineage enriched" "Detected in many" 41 "T-cells: 60.9" "Cell line enriched" "Detected in some" 17 "HDLM-2: 206.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031613 Approved Supported "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA031613: AB_10601096" "unprognostic (4.63e-3)" "unprognostic (8.70e-3)" "unprognostic (2.82e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (4.59e-7)" "unprognostic (3.02e-1)" "unprognostic (5.05e-3)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (5.53e-4)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" 0.5 0.2 0.3 8.6 0.3 1.7 0.6 0.8 0.7 0.6 0.2 0.9 0.6 0.4 0.3 1.2 0.2 3.3 0.2 0.4 0.4 0.3 0.6 1.7 7.0 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.4 0.8 1.2 0.1 0.5 0.1 2.0 2.1 1.5 0.6 0.0 3.2 1.4 0.8 0.2 13.0 0.3 0.1 8.0 5.4 0.2 0.7 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 206.5 0.0 12.2 0.7 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.2 0.0 5.8 3.2 0.8 0.0 0.0 1.8 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.5 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.2 0.1 0.2 0.2 0.2 0.0 1.4 0.3 0.3 0.4 0.3 0.4 0.3 11.5 3.4 0.1 0.4 0.3 0.3 1.1 0.3 0.3 0.4 60.9 1.7 0.3 0.3 0.8 0.7 0.4 0.4 0.2 0.1 0.4 0.0 0.2 0.7 0.1 0.0 0.6 0.0 0.4 0.4 0.7 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.5 0.0 0.4 0.1 0.1 5.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.7 0.8 0.0 0.5 0.2 0.0 1.8 0.0 0.1 0.0 7.8 0.0 0.0 0.6 CCR5 "CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22" ENSG00000160791 "C-C motif chemokine receptor 5" P51681 3 46370854-46376206 "CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "Kupffer cells: 5.5;Langerhans cells: 32.6;Macrophages: 12.8;T-cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 39.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "JURKAT: 1.4;Karpas-707: 6.8;U-266/84: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (4.32e-3)" "unprognostic (1.94e-3)" "unprognostic (1.89e-3)" "prognostic favorable (7.42e-5)" "unprognostic (1.80e-2)" "prognostic favorable (9.33e-5)" "unprognostic (3.38e-3)" "unprognostic (9.90e-3)" "unprognostic (7.65e-2)" "unprognostic (6.22e-2)" "unprognostic (1.36e-1)" "unprognostic (5.34e-2)" "unprognostic (1.14e-3)" "unprognostic (8.34e-2)" "unprognostic (4.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.42e-2)" 1.8 2.0 0.5 15.0 0.6 1.3 2.4 0.6 0.7 2.1 1.0 3.3 4.1 1.4 1.0 1.4 1.7 5.0 1.1 0.4 0.8 1.0 3.4 7.4 14.4 1.6 0.9 1.7 0.6 0.6 0.4 0.7 1.3 1.9 3.9 0.1 2.9 1.0 0.3 1.1 5.8 3.2 1.2 9.4 6.8 0.8 1.2 4.2 0.8 0.2 9.4 4.8 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 6.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 3.1 0.0 0.0 0.1 0.0 12.0 2.2 0.0 11.0 3.8 39.7 0.5 4.7 16.1 9.5 0.0 0.4 4.1 0.5 6.3 0.0 9.0 8.0 3.2 0.5 0.6 0.6 0.7 0.4 0.8 1.6 0.9 1.3 1.2 1.2 2.4 0.3 0.0 1.7 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.3 1.5 0.0 1.3 0.0 1.4 0.3 4.7 0.0 0.0 0.0 0.0 5.5 32.6 0.0 0.0 12.8 3.6 1.9 1.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 13.1 0.1 0.0 0.1 CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 35.0;Erythroid cells: 26.5;Hofbauer cells: 42.7;Kupffer cells: 22.1;Langerhans cells: 36.5;Macrophages: 56.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 21.0;OE19: 8.4;PC-3: 15.3;RT4: 8.3;TIME: 15.4;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043238 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" 11.7 1.6 2.1 11.4 2.1 9.0 8.4 2.2 3.7 2.3 2.2 11.5 11.7 1.2 0.6 0.9 1.1 5.5 2.7 2.1 2.2 2.2 4.4 12.4 4.9 2.8 2.3 0.5 1.5 0.8 0.8 5.1 3.1 0.8 10.4 0.2 0.9 0.8 1.1 0.7 12.1 2.5 2.6 8.5 5.5 0.3 2.9 7.7 1.3 1.1 3.8 6.0 1.1 3.3 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.2 0.0 0.2 0.0 0.0 2.8 0.0 0.0 0.3 0.7 4.6 0.0 21.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 5.0 0.2 0.0 7.2 4.2 2.8 0.1 5.0 0.0 1.6 2.6 0.0 8.4 15.3 0.4 0.3 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 15.4 0.6 0.3 0.7 0.3 0.0 8.6 0.2 7.5 6.5 0.0 8.7 15.4 4.3 2.8 22.1 3.4 1.7 1.6 4.7 9.9 3.9 1.0 2.5 2.6 6.7 10.1 3.0 4.7 5.0 2.1 2.1 2.2 3.7 2.1 2.2 2.8 2.3 3.1 2.6 2.9 3.3 35.0 0.0 4.7 0.0 4.4 2.0 0.2 0.2 0.0 0.0 0.4 0.4 1.1 1.5 1.2 0.0 0.0 0.3 4.5 19.5 0.0 0.6 0.1 0.1 0.2 12.1 0.0 26.5 0.0 8.8 1.2 1.4 4.6 0.1 9.5 0.1 6.4 0.4 42.7 0.0 0.0 16.6 0.0 22.1 36.5 0.0 0.0 56.2 1.8 1.9 6.7 0.0 0.0 0.0 0.0 9.8 12.4 0.0 4.2 0.2 17.2 0.2 0.6 0.0 0.0 0.6 0.5 0.0 0.0 0.0 1.1 2.5 6.4 0.4 9.2 1.1 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD1C CD1 ENSG00000158481 "CD1c molecule" P29017 1 158289923-158294774 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 130.4" "Cell type enriched" "Detected in some" 6 "Langerhans cells: 551.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 84.1;myeloid DC: 324.9" "Group enriched" "Detected in many" 8 "B-cells: 84.1;dendritic cells: 324.9" "Group enriched" "Detected in some" 10 "JURKAT: 14.8;MOLT-4: 49.4" HPA068359 Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA 200000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "Endoplasmic reticulum" "HPA068359: " "unprognostic (2.55e-3)" "prognostic favorable (1.79e-5)" "unprognostic (1.75e-5)" "unprognostic (3.09e-5)" "unprognostic (3.12e-2)" "unprognostic (8.13e-3)" "unprognostic (2.01e-1)" "unprognostic (3.80e-3)" "unprognostic (7.11e-3)" "unprognostic (1.87e-1)" "unprognostic (7.41e-2)" "unprognostic (1.93e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (8.05e-2)" "unprognostic (1.99e-1)" 2.7 0.8 0.0 17.3 0.0 1.1 5.0 0.0 0.2 2.3 0.0 3.4 2.0 2.4 0.6 4.5 1.8 7.7 2.0 0.0 0.0 1.2 4.1 6.5 26.2 0.0 0.0 0.9 0.7 0.6 0.2 0.1 0.0 1.8 9.4 0.0 2.8 1.3 1.0 12.2 12.0 3.1 0.0 23.0 3.7 0.9 0.0 130.4 0.7 1.1 38.2 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 49.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.9 0.0 0.6 26.8 0.1 0.1 24.7 0.3 84.1 0.1 0.0 324.9 49.1 0.2 0.0 1.1 4.1 3.7 1.5 0.5 15.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.2 0.0 26.6 13.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 4.1 0.0 0.1 1.5 0.0 0.8 0.0 0.0 0.1 1.4 0.0 0.0 3.8 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 7.1 551.4 4.5 0.0 91.2 19.6 0.0 11.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.5 0.0 0.0 0.2 0.4 0.1 0.3 0.0 7.4 0.0 1.9 0.0 0.0 0.0 CD1E ENSG00000158488 "CD1e molecule" P15812 1 158353696-158357553 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 69 "lymphoid tissue: 962.6" "Cell type enriched" "Detected in some" 13 "Langerhans cells: 549.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 14 "myeloid DC: 62.5" "Lineage enriched" "Detected in many" 14 "dendritic cells: 62.5" "Cell line enriched" "Detected in some" 43 "MOLT-4: 1276.2" "Not detected" "Not detected" "HPA057769, HPA070634" Uncertain Supported "Nucleoli,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Nucleoli "HPA057769: AB_2683522, HPA070634: " "unprognostic (7.94e-3)" "unprognostic (1.85e-5)" "unprognostic (1.47e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.33e-1)" "unprognostic (1.54e-3)" "unprognostic (1.24e-1)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (8.55e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (2.49e-1)" "unprognostic (8.50e-2)" "unprognostic (2.45e-1)" 0.7 0.5 0.0 4.4 0.0 0.0 1.8 0.0 0.0 2.1 0.0 2.1 2.2 1.1 0.4 7.9 0.9 4.8 1.0 0.0 0.0 0.8 1.5 3.1 6.4 0.0 0.0 0.6 0.3 0.5 0.1 0.0 0.0 1.1 5.6 0.0 1.5 0.6 0.4 13.9 2.8 0.9 0.0 5.1 4.7 0.5 0.0 962.6 0.8 0.2 9.9 2.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 29.8 0.1 0.0 0.0 0.5 1276.2 0.0 0.3 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 2.5 0.2 0.0 0.0 0.0 62.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.5 0.0 0.8 8.4 0.0 0.0 0.6 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.7 0.0 0.0 1.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 4.8 549.5 0.0 0.0 41.7 8.8 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 7.1 0.1 0.7 0.0 0.0 0.0 CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 6 "dendritic cells: 158.3;NK-cells: 178.2;T-cells: 476.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 25 "HDLM-2: 224.1;JURKAT: 145.8;MOLT-4: 166.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" 4.6 4.6 0.6 51.3 0.7 11.4 7.6 0.6 1.0 5.8 0.8 13.9 17.2 3.7 2.8 8.4 4.2 16.8 2.6 0.5 0.8 2.5 7.8 21.0 119.6 1.7 0.7 2.8 2.9 0.9 0.7 1.0 1.1 5.2 16.0 0.0 8.6 2.3 1.4 3.5 28.4 4.4 1.0 44.1 24.1 1.8 1.0 249.8 3.8 1.7 79.1 20.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.1 0.0 0.4 0.0 0.0 0.0 0.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.1 0.5 0.0 0.0 166.9 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.4 0.0 11.3 5.2 1.6 421.8 3.7 403.1 3.8 610.2 714.1 95.4 2.5 316.3 486.2 14.1 1108.0 2.8 21.0 655.2 565.1 0.6 0.7 0.6 1.0 0.5 0.8 1.7 0.7 1.1 1.0 1.0 1.1 5.0 3.2 17.5 0.0 12.3 5.0 0.4 0.0 2.2 0.0 4.0 4.7 2.1 0.0 2.5 3.7 0.0 0.1 158.3 0.2 0.0 0.5 23.5 1.1 1.0 2.9 3.0 24.0 0.0 0.0 0.0 2.5 10.7 0.9 5.1 0.0 8.2 1.5 0.6 0.0 0.0 0.0 0.0 10.9 16.6 7.8 0.6 19.1 1.8 1.0 15.5 0.0 178.2 0.0 0.0 0.0 0.0 0.4 42.3 0.1 0.0 1.7 0.0 0.0 0.0 2.9 4.1 0.3 0.2 0.4 3.7 0.0 476.8 0.0 0.5 0.2 CD247 "CD3H, CD3Q, CD3Z" ENSG00000198821 "CD247 molecule" P20963 1 167430640-167518610 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 49.0;lymphoid tissue: 179.4" "Group enriched" "Detected in many" 9 "dendritic cells: 492.1;NK-cells: 727.1;T-cells: 247.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "gdT-cell: 376.4;MAIT T-cell: 208.9;memory CD4 T-cell: 190.0;memory CD8 T-cell: 219.7;naive CD4 T-cell: 237.8;naive CD8 T-cell: 195.1;NK-cell: 225.3;T-reg: 254.5" "Group enriched" "Detected in all" 32 "NK-cells: 225.3;T-cells: 376.4" "Group enriched" "Detected in some" 25 "HDLM-2: 155.9;JURKAT: 113.1;MOLT-4: 167.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004651, HPA008750" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB004651: AB_425347, HPA008750: AB_1857863" "prognostic favorable (9.12e-4)" "unprognostic (3.21e-3)" "unprognostic (7.09e-3)" "prognostic favorable (8.63e-6)" "unprognostic (1.99e-2)" "prognostic favorable (3.98e-4)" "unprognostic (1.79e-2)" "unprognostic (1.11e-2)" "unprognostic (5.46e-3)" "unprognostic (9.73e-3)" "unprognostic (1.33e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (1.60e-1)" "unprognostic (5.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.94e-3)" 3.2 1.7 2.3 25.3 2.3 49.0 1.9 2.2 2.5 1.9 1.9 4.3 7.1 2.3 3.1 2.1 1.8 5.5 1.3 2.3 2.3 2.0 5.4 10.9 57.7 2.3 2.2 0.8 0.8 0.5 0.8 1.4 2.2 1.8 4.6 0.2 2.4 1.6 1.4 1.1 14.3 1.5 2.1 40.2 7.0 0.4 2.9 179.4 2.5 0.9 36.4 7.3 1.9 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 155.9 0.3 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 113.1 0.0 0.1 0.0 0.0 167.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 8.3 1.0 0.4 376.4 1.4 208.9 9.3 190.0 219.7 1.5 4.9 237.8 195.1 8.7 225.3 1.2 2.8 254.5 231.2 2.3 2.3 2.2 2.5 2.3 2.3 2.3 2.2 2.2 2.1 2.9 2.5 3.4 3.2 16.0 3.3 8.2 1.5 0.1 0.0 0.6 0.4 3.5 3.2 0.6 1.5 1.3 0.0 0.0 0.1 492.1 0.4 0.0 0.5 0.2 0.7 0.8 1.8 0.0 14.7 8.8 0.0 0.1 2.2 6.1 1.1 6.3 0.4 7.1 1.4 0.3 3.3 9.4 0.5 0.0 7.8 1.4 0.2 0.0 5.9 3.6 14.0 7.6 0.1 727.1 0.5 3.7 0.0 1.2 0.0 51.9 0.1 0.2 1.3 2.2 0.2 0.0 0.9 1.2 0.1 2.5 1.4 0.6 0.1 247.2 0.0 0.1 0.1 CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 155.4;Fibroblasts: 166.9;Leydig cells: 74.9;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Cell line enhanced" "Detected in many" "ASC diff: 492.4;ASC TERT1: 481.9;BJ: 222.2;BJ hTERT+: 330.1;fHDF/TERT166: 451.1;HSkMC: 516.8;U-2197: 794.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" 237.3 12.9 2.3 39.3 2.4 0.4 155.5 2.2 4.0 87.2 1.5 31.7 7.8 52.2 6.9 19.6 60.8 32.3 30.3 2.2 2.2 18.7 3.6 36.5 6.2 2.4 2.6 23.9 11.7 3.3 8.8 67.4 2.2 17.8 7.4 0.4 18.2 19.4 15.8 51.0 27.2 26.5 2.0 7.2 26.3 5.0 3.9 5.3 35.0 6.5 2.6 63.4 61.5 2.0 0.0 0.0 4.9 0.0 492.4 481.9 0.3 222.2 330.1 16.3 15.1 0.1 0.0 0.0 5.8 451.1 0.0 0.0 0.2 0.2 3.5 0.0 0.0 0.0 0.1 3.3 97.5 0.0 0.0 516.8 0.0 21.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.4 3.2 2.5 0.0 1.4 9.5 0.0 0.2 0.0 0.0 2.8 7.6 0.0 1.2 0.0 13.4 0.5 0.4 0.1 0.0 0.8 794.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 2.6 0.0 0.1 3.1 21.8 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.4 2.2 4.0 2.2 2.2 2.4 2.6 2.2 2.0 3.9 2.0 15.0 0.0 0.0 1.3 1.3 12.5 0.0 0.0 0.6 0.1 1.2 1.5 2.2 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.3 5.3 155.4 5.8 0.0 0.0 0.0 0.0 2.5 166.9 13.3 3.1 0.0 0.0 2.5 0.0 6.0 0.0 0.0 0.0 0.0 0.3 14.4 2.3 74.9 1.6 12.4 1.9 0.6 2.9 1.0 0.0 0.0 0.3 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.1 32.9 5.5 59.3 0.1 0.1 0.8 8.2 4.4 6.9 1.1 0.0 0.1 CD28 ENSG00000178562 "CD28 molecule" P10747 2 203706475-203738912 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 30.8;placenta: 14.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 34.1;T-cells: 52.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 101.9" "Lineage enriched" "Detected in many" 7 "T-cells: 101.9" "Group enriched" "Detected in some" 14 "Karpas-707: 360.6;RPMI-8226: 173.2;U-266/70: 294.1;U-266/84: 283.7" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Not detected" "Not detected" HPA070003 Enhanced NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA070003: AB_2686226" "unprognostic (5.54e-2)" "unprognostic (2.16e-4)" "unprognostic (1.90e-3)" "unprognostic (2.49e-3)" "unprognostic (3.44e-2)" "unprognostic (6.07e-5)" "unprognostic (9.09e-2)" "unprognostic (4.66e-2)" "unprognostic (3.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-1)" "unprognostic (1.68e-1)" "unprognostic (5.78e-5)" "unprognostic (4.77e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (8.96e-2)" 4.0 0.3 0.0 14.9 0.1 3.3 0.8 0.1 0.1 1.1 0.9 1.7 1.1 0.7 0.3 0.9 0.5 4.1 0.6 0.1 0.1 0.5 1.3 1.9 28.0 0.1 0.0 0.3 0.5 0.2 0.1 14.8 0.1 1.0 1.9 0.1 0.6 0.8 0.3 0.3 3.0 1.4 0.1 7.2 2.5 0.7 0.2 30.8 0.5 0.1 18.6 4.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.7 2.0 0.0 360.6 0.2 0.0 19.9 0.0 0.1 0.0 0.0 0.1 0.3 173.2 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.1 0.3 294.1 283.7 2.9 0.3 0.1 0.0 1.7 0.6 1.0 8.3 0.5 50.6 0.3 54.5 26.1 0.1 0.3 48.1 18.6 13.8 0.2 0.5 0.2 101.9 14.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.5 0.0 1.3 0.0 2.4 2.9 0.1 0.0 0.6 0.0 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.2 3.2 0.1 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.3 1.0 2.0 0.1 1.3 0.0 0.0 0.1 34.1 0.0 0.0 0.0 0.0 0.8 5.3 0.2 0.0 4.4 0.0 1.0 1.5 0.0 2.1 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.2 1.6 0.1 52.6 0.0 0.0 0.0 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CD3D T3D ENSG00000167286 "CD3d molecule" P04234 11 118339075-118342705 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "lymphoid tissue: 906.7" "Group enriched" "Detected in many" 14 "dendritic cells: 231.0;T-cells: 665.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 52 "gdT-cell: 1462.4;MAIT T-cell: 990.0;memory CD4 T-cell: 1206.1;memory CD8 T-cell: 1368.7;naive CD4 T-cell: 1091.4;naive CD8 T-cell: 1338.9;T-reg: 1660.4" "Lineage enriched" "Detected in all" 66 "T-cells: 1660.4" "Group enriched" "Detected in some" 4 "JURKAT: 621.5;MOLT-4: 1299.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013055, HPA071778" Enhanced Uncertain "Endoplasmic reticulum" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "CAB013055: , HPA071778: " "prognostic favorable (3.00e-4)" "prognostic favorable (8.46e-5)" "unprognostic (1.05e-2)" "prognostic favorable (1.73e-7)" "unprognostic (6.00e-2)" "prognostic favorable (1.70e-4)" "unprognostic (3.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.24e-3)" "unprognostic (1.01e-2)" "unprognostic (5.69e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (9.00e-2)" "unprognostic (2.02e-1)" "unprognostic (3.66e-2)" "prognostic favorable (6.16e-4)" 4.1 3.8 0.3 77.5 0.4 28.6 9.9 0.4 1.4 5.2 0.7 18.8 21.7 3.6 5.7 7.6 4.5 15.7 3.7 0.3 0.6 2.3 7.9 20.6 222.7 1.1 0.4 3.2 1.3 0.9 0.8 1.2 0.6 5.9 22.4 0.3 8.3 3.1 2.5 4.0 30.1 3.9 0.7 60.9 23.8 2.4 0.5 906.7 3.8 1.4 166.9 26.7 3.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 621.5 49.8 0.0 0.0 0.0 1299.8 237.2 1.2 0.0 0.0 0.7 0.1 0.5 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.2 0.8 0.0 0.5 0.0 1.5 1.1 0.0 0.9 1.1 0.4 0.0 0.1 0.0 10.1 5.3 4.6 1462.4 3.3 990.0 9.6 1206.1 1368.7 5.0 3.7 1091.4 1338.9 25.1 4.2 5.3 6.0 1660.4 1138.7 0.3 0.4 0.4 1.4 0.3 0.6 1.1 0.4 0.6 0.7 0.5 0.8 5.9 6.4 29.6 0.0 18.6 15.3 0.3 0.0 1.8 0.0 5.4 6.7 2.8 7.2 2.6 3.7 0.0 0.4 231.0 0.9 0.0 1.3 0.4 0.8 0.8 5.0 1.2 16.8 0.0 0.0 0.0 8.3 21.4 0.9 12.6 0.0 7.9 3.1 0.6 0.0 0.0 0.2 0.0 14.9 28.4 0.7 0.0 14.2 12.4 1.0 25.0 0.0 32.0 0.0 0.0 0.1 0.2 0.0 21.0 0.3 0.0 3.4 1.5 0.0 0.0 2.5 5.8 0.1 1.2 1.4 11.8 0.3 665.7 0.0 1.1 0.2 CD3E ENSG00000198851 "CD3e molecule" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 640.4" "Group enriched" "Detected in many" 7 "dendritic cells: 213.6;NK-cells: 154.5;T-cells: 601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 490.6;MAIT T-cell: 420.8;memory CD4 T-cell: 414.4;memory CD8 T-cell: 463.5;naive CD4 T-cell: 491.7;naive CD8 T-cell: 501.3;NK-cell: 202.2;T-reg: 426.3" "Group enriched" "Detected in all" 21 "NK-cells: 202.2;T-cells: 501.3" "Group enriched" "Detected in some" 67 "JURKAT: 544.9;MOLT-4: 764.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" 6.4 5.6 0.9 85.8 1.1 36.7 6.7 0.9 1.2 7.1 1.3 15.3 22.0 5.8 4.6 9.5 5.4 20.1 3.8 0.7 1.0 3.5 9.7 23.0 209.6 1.8 0.9 3.8 2.2 0.7 1.0 1.6 1.4 6.6 19.3 0.0 11.6 3.0 1.9 5.4 36.4 5.1 1.2 78.9 24.4 1.7 1.3 640.4 5.3 1.6 147.0 24.8 4.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 544.9 0.9 2.0 0.0 0.0 764.9 0.6 0.3 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 1.6 8.0 9.8 0.0 0.6 0.0 16.4 1.8 2.4 490.6 1.3 420.8 1.6 414.4 463.5 1.5 2.1 491.7 501.3 12.2 202.2 2.0 8.6 426.3 333.0 0.9 1.1 0.9 1.2 0.7 1.0 1.8 0.9 1.4 1.2 1.3 1.6 4.9 0.0 8.6 0.0 12.9 5.2 0.3 0.0 0.0 0.0 3.8 4.8 0.3 0.0 0.6 1.8 0.0 0.2 213.6 0.4 0.0 0.2 7.0 0.5 0.9 2.5 0.0 6.9 0.1 0.0 0.0 5.3 24.5 0.9 7.6 0.0 8.9 2.4 0.3 0.0 0.1 0.0 0.0 7.6 8.3 0.2 0.0 12.6 12.4 1.0 8.4 0.0 154.5 0.0 0.1 0.0 1.1 0.0 41.4 0.1 0.2 2.1 0.0 0.0 0.0 1.3 2.7 0.0 0.0 1.6 5.4 0.3 601.4 0.0 0.6 0.3 CD3G ENSG00000160654 "CD3g molecule" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 94.7" "Group enriched" "Detected in many" 11 "dendritic cells: 139.6;T-cells: 294.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 21 "gdT-cell: 229.0;MAIT T-cell: 135.6;memory CD4 T-cell: 187.3;memory CD8 T-cell: 197.3;naive CD4 T-cell: 192.6;naive CD8 T-cell: 241.7;T-reg: 200.0" "Lineage enriched" "Detected in many" 26 "T-cells: 241.7" "Group enriched" "Detected in some" 52 "JURKAT: 70.9;MOLT-4: 193.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" 0.7 0.8 0.6 10.5 0.8 1.3 1.0 1.1 0.8 0.7 1.1 2.3 3.3 0.5 0.6 1.4 0.9 2.5 0.5 0.5 0.4 0.6 1.6 2.8 27.9 0.9 0.6 0.4 0.5 0.2 0.0 0.3 0.8 0.9 2.7 0.4 1.6 0.3 10.5 0.9 4.6 0.6 0.3 11.5 4.1 0.4 0.8 94.7 0.6 0.3 20.4 3.0 0.4 1.9 0.2 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.2 0.7 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.6 0.0 0.4 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 70.9 2.5 0.3 0.0 0.6 193.8 1.3 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.2 0.7 0.3 0.2 0.2 0.1 9.2 1.2 1.2 229.0 0.6 135.6 0.8 187.3 197.3 0.6 0.9 192.6 241.7 6.4 1.4 1.2 1.5 200.0 90.4 0.6 0.8 1.1 0.8 0.5 0.4 0.9 0.6 0.8 0.3 0.8 1.9 3.2 3.2 6.9 0.0 7.8 2.3 0.1 0.0 1.8 0.2 2.0 2.9 0.8 1.5 1.9 0.0 0.0 0.1 139.6 0.4 0.0 0.3 1.0 0.4 0.4 1.4 0.0 3.4 0.1 0.0 0.0 2.3 13.7 0.4 6.3 0.0 4.2 1.7 0.1 0.0 0.1 0.2 0.0 3.8 5.8 1.4 0.0 7.7 5.4 1.0 8.1 0.0 14.4 0.0 0.3 0.0 0.1 0.0 18.5 0.0 0.0 0.6 0.7 0.8 0.0 1.3 1.6 0.2 0.4 0.6 2.4 0.3 294.0 0.1 0.3 0.0 CD40LG "CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.5" "Cell type enriched" "Detected in some" 8 "T-cells: 76.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 26.3;MAIT T-cell: 64.1;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.1" "Lineage enriched" "Detected in many" 39 "T-cells: 80.5" "Cell line enriched" "Detected in some" 15 "MOLT-4: 23.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 776000 20000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" 0.8 0.3 0.1 7.9 0.0 1.9 1.1 0.2 0.2 0.9 0.2 1.9 1.8 0.3 0.2 1.0 0.4 2.0 0.2 0.1 0.2 0.4 1.0 2.4 15.5 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.8 3.1 0.0 0.6 0.3 0.1 0.6 3.8 0.6 0.0 4.9 2.0 0.3 0.1 15.5 0.5 0.2 14.8 2.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.3 26.3 0.1 64.1 0.1 80.5 11.7 0.2 0.0 76.1 0.7 1.3 0.8 0.1 0.1 10.5 13.6 0.1 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.1 0.2 0.6 0.0 2.4 0.0 2.4 1.3 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 1.7 0.0 0.0 0.0 0.6 2.6 0.0 1.3 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.6 4.0 8.9 0.0 2.9 1.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.1 2.0 0.0 76.6 0.0 0.0 0.1 CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 504.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 999.7;Ductal cells: 992.1;Exocrine glandular cells: 869.6;Langerhans cells: 1934.2;Suprabasal keratinocytes: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1650.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 1200000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" 143.7 42.4 29.2 218.0 33.9 308.1 164.7 63.0 25.1 146.0 16.8 91.1 53.0 200.4 20.1 227.8 69.0 129.7 30.4 33.0 116.5 31.3 31.0 214.1 108.8 114.9 102.3 11.7 263.2 6.0 8.1 74.1 118.3 87.3 111.5 38.0 504.2 57.0 17.1 433.3 60.8 175.8 114.3 83.8 61.5 6.6 62.8 64.2 76.2 27.7 188.7 235.2 193.4 114.9 493.0 448.6 4.3 1.2 252.6 691.5 1.6 962.2 740.3 521.3 288.2 30.4 150.4 0.7 126.5 1350.2 1065.4 820.1 9.9 1013.9 716.4 110.3 6.2 18.9 198.3 0.3 262.3 254.6 1124.3 315.4 778.3 693.2 552.7 1650.0 184.3 0.1 4.0 157.9 518.9 3.0 25.6 166.9 9.8 8.7 136.4 1.4 89.3 7.5 777.4 138.1 2.0 1.4 185.2 5.5 462.8 38.6 25.7 15.1 547.3 646.6 120.0 815.8 1006.0 281.6 327.7 3.7 980.4 145.1 969.8 127.4 403.0 35.4 140.6 257.8 196.5 122.5 210.1 186.5 229.0 90.0 179.7 153.6 92.6 322.3 356.1 79.9 309.7 437.3 29.2 33.9 63.0 25.1 33.0 116.5 114.9 102.3 118.3 114.3 62.8 114.9 41.0 96.1 361.8 54.5 250.1 999.7 297.7 335.3 228.2 0.6 139.6 71.2 8.6 27.1 125.6 20.2 2.1 4.5 257.0 14.0 1.9 992.1 41.3 43.6 395.4 50.9 100.1 94.4 0.4 869.6 3.6 282.2 39.8 196.9 763.2 25.2 13.2 3.6 226.6 0.0 0.4 93.3 30.5 474.3 1934.2 24.3 22.4 523.9 604.7 8.4 594.2 29.6 62.8 0.5 11.2 813.1 10.9 0.4 216.3 386.7 6.0 1.6 18.8 2.0 157.8 197.2 227.9 0.4 0.4 279.3 1024.9 17.9 430.8 1.0 79.1 330.7 CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 148.4;lymphoid tissue: 283.9" "Cell type enhanced" "Detected in many" "B-cells: 336.1;dendritic cells: 251.2;Kupffer cells: 245.8;Macrophages: 218.3;monocytes: 366.6;NK-cells: 454.2;T-cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 220.9;HMC-1: 236.9;U-266/70: 501.4;U-266/84: 360.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 2000000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" 11.8 5.9 1.4 115.3 1.5 148.4 18.8 1.5 4.7 10.2 2.3 24.9 20.5 6.7 5.0 8.4 5.7 26.6 4.3 1.3 1.7 4.4 19.9 31.0 283.9 2.6 1.8 3.1 2.0 1.6 1.6 5.8 2.7 8.1 32.5 0.1 14.0 4.4 2.9 3.5 48.3 12.5 2.1 160.0 32.5 2.9 3.2 138.9 5.2 3.4 256.8 41.8 4.5 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 220.9 0.1 0.0 0.0 0.5 0.1 0.0 0.0 6.0 0.0 2.1 0.0 0.0 0.0 27.1 236.9 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.4 78.6 0.0 0.0 78.9 38.4 0.1 0.0 0.0 4.7 0.1 34.3 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.3 0.2 0.4 501.4 360.3 89.9 0.2 66.7 0.1 218.1 327.1 230.8 242.8 470.2 335.8 206.2 275.2 283.4 329.7 161.2 277.9 301.6 82.1 160.7 487.4 57.0 229.9 603.5 1.4 1.5 1.5 4.7 1.3 1.7 2.6 1.8 2.7 2.1 3.2 4.1 3.7 0.0 9.6 0.7 336.1 5.5 0.8 0.0 1.8 0.0 2.0 1.7 1.1 2.8 1.3 3.7 0.0 0.6 251.2 0.1 1.9 0.2 0.1 0.7 0.5 2.8 1.2 21.5 0.1 0.2 0.8 2.4 6.6 0.6 90.7 0.1 7.1 2.0 86.4 0.0 0.1 0.1 0.0 245.8 106.5 0.5 1.8 218.3 39.2 1.0 366.6 0.0 454.2 0.5 0.0 0.1 0.0 0.4 127.4 0.4 0.0 4.9 2.2 0.0 0.0 1.7 2.1 0.5 0.3 0.7 3.0 0.4 376.2 0.0 1.2 0.5 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD79A "IGA, MB-1" ENSG00000105369 "CD79a molecule" P11912 19 41877279-41881372 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 152.3;lymphoid tissue: 545.2" "Group enriched" "Detected in some" 5 "B-cells: 1186.4;Plasma cells: 956.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "memory B-cell: 1273.8;naive B-cell: 1457.5" "Lineage enriched" "Detected in all" 40 "B-cells: 1457.5" "Group enriched" "Detected in some" 22 "Daudi: 1598.7;REH: 491.0;U-698: 1366.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000019, HPA056444" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB000019: AB_2244527, HPA056444: " "prognostic favorable (8.45e-5)" "unprognostic (1.63e-3)" "unprognostic (4.13e-3)" "unprognostic (1.31e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.23e-2)" "unprognostic (8.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.12e-2)" "unprognostic (2.53e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (6.08e-2)" "unprognostic (3.39e-1)" "unprognostic (1.17e-1)" "unprognostic (1.46e-1)" 4.8 4.9 0.2 213.4 0.2 47.2 9.5 0.2 0.4 3.6 0.1 47.3 37.9 2.4 1.4 9.9 1.8 13.0 2.9 0.1 0.1 3.4 2.6 8.9 482.4 0.3 0.2 3.7 0.6 0.1 0.3 1.2 0.2 4.3 28.9 0.0 28.5 2.2 0.7 0.4 152.3 2.2 0.6 286.5 76.9 2.4 0.2 93.7 8.1 0.4 545.2 32.3 1.9 0.3 1.1 0.8 0.3 0.1 0.2 0.7 0.2 0.2 0.0 0.3 0.0 0.0 0.1 1598.7 1.2 0.0 0.1 0.0 0.2 0.2 0.0 0.5 0.7 2.7 0.0 1.7 0.2 2.6 1.8 0.5 0.6 0.2 0.0 0.0 0.0 8.0 3.1 0.4 0.1 1.1 1.6 9.9 0.1 0.1 0.4 491.0 0.8 2.5 0.1 0.0 0.5 0.5 0.8 0.5 1.3 0.0 0.0 4.8 1.6 0.1 4.3 0.3 0.8 7.8 1.4 1366.7 0.0 52.1 0.1 12.4 1.5 6.9 1.7 1.8 0.7 1273.8 4.1 2.1 2.5 1457.5 4.9 26.3 4.6 2.6 4.3 36.3 10.4 62.7 0.2 0.2 0.2 0.4 0.1 0.1 0.3 0.2 0.2 0.6 0.2 0.3 0.2 0.0 2.4 0.0 1186.4 1.8 0.5 0.5 0.6 0.0 0.7 0.9 0.2 1.5 0.2 0.0 0.0 0.2 18.2 0.7 0.0 1.8 0.2 0.1 0.3 0.5 0.0 10.5 0.0 25.6 0.4 2.2 6.6 0.2 0.0 0.4 2.2 1.0 0.8 0.0 0.0 0.4 0.0 4.1 1.4 0.0 0.3 5.3 138.7 0.0 6.3 0.0 15.5 0.0 0.0 181.7 0.4 0.4 956.7 0.3 0.2 0.9 0.0 0.0 0.0 0.2 0.7 0.3 0.6 0.9 1.4 0.1 23.5 0.2 5.3 0.2 CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Group enriched" "Detected in many" 4 "dendritic cells: 111.7;T-cells: 242.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Cell line enhanced" "Detected in some" "JURKAT: 4.0;MOLT-4: 15.2;RPMI-8226: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" 5.3 4.6 2.1 21.2 2.8 22.5 4.7 1.9 3.0 3.8 1.4 4.9 11.8 3.0 3.6 4.4 4.0 9.8 2.3 2.1 2.1 1.8 7.4 10.5 45.0 2.8 2.1 2.5 2.6 1.1 1.5 0.6 2.5 3.4 5.9 0.2 8.3 1.9 0.8 1.3 20.7 2.4 2.2 117.1 16.4 1.0 2.3 369.0 4.4 0.4 21.4 9.1 4.0 2.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.6 15.2 0.9 0.5 0.1 0.2 0.1 0.7 3.3 0.0 0.3 0.7 1.9 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 30.0 0.3 234.4 0.6 2.3 523.0 0.4 0.6 2.2 476.8 4.3 27.9 0.9 1.2 0.8 152.4 2.1 2.8 1.9 3.0 2.1 2.1 2.8 2.1 2.5 2.2 2.3 2.1 2.2 0.0 4.6 0.0 5.7 2.0 0.2 0.0 0.0 0.3 1.5 1.5 3.4 1.5 0.6 0.0 0.0 0.0 111.7 0.2 0.0 0.2 0.3 0.5 0.3 1.3 0.0 7.8 4.2 0.0 0.0 2.6 8.2 0.4 2.5 0.0 6.4 2.3 0.1 0.0 3.1 0.3 0.0 1.9 11.5 0.2 0.0 6.6 0.0 1.0 5.9 0.1 38.1 0.0 0.2 0.0 0.0 0.0 30.8 0.2 0.0 0.4 1.5 0.4 0.0 1.1 1.4 0.4 0.4 1.1 1.8 0.1 242.4 0.0 0.6 0.1 CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Group enriched" "Detected in many" 8 "dendritic cells: 53.2;T-cells: 162.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Cell line enriched" "Detected in some" 60 "RPMI-8226: 1113.4" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" 1.9 1.9 0.4 10.6 0.3 8.3 2.9 1.1 0.6 33.4 0.1 2.1 5.0 1.2 1.1 1.6 1.5 4.3 1.0 0.1 1.2 1.0 1.6 4.2 25.9 5.0 2.1 0.9 0.9 4.6 8.8 0.3 4.8 1.7 3.0 0.0 2.4 1.0 0.6 1.4 15.1 1.1 0.7 15.6 5.1 0.4 2.4 459.6 2.0 0.4 15.1 3.4 1.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.1 0.2 0.0 1113.4 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 42.0 1.0 0.8 15.7 1.1 79.3 0.7 1.9 601.8 0.6 1.2 4.6 1053.9 6.1 1.1 1.7 1.0 2.2 427.6 0.4 0.3 1.1 0.6 0.1 1.2 5.0 2.1 4.8 0.7 2.4 0.5 1.3 6.4 5.5 0.0 4.4 4.0 2.2 0.0 0.6 0.0 2.2 2.8 1.0 1.5 0.0 0.0 0.0 0.1 53.2 0.1 0.0 0.1 0.5 0.2 0.5 0.7 0.0 1.7 0.4 0.0 0.0 2.0 7.1 0.2 0.0 0.0 0.7 0.5 0.1 0.0 0.5 4.6 0.0 4.0 4.3 0.5 0.0 4.1 5.4 5.6 7.5 0.0 10.3 0.0 0.1 0.0 0.1 0.0 10.8 0.7 12.4 0.2 0.0 0.0 0.0 2.0 1.2 0.2 0.1 0.5 2.8 0.0 162.9 0.0 7.5 0.3 CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.8" "Group enriched" "Detected in many" 4 "dendritic cells: 96.8;NK-cells: 58.7;T-cells: 199.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.2;memory CD4 T-cell: 67.0;memory CD8 T-cell: 85.3;naive CD4 T-cell: 68.7;naive CD8 T-cell: 81.8;NK-cell: 79.5;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.5;T-cells: 117.2" "Cell line enhanced" "Detected in some" "HEL: 15.9;JURKAT: 18.2;MOLT-4: 68.7;RT4: 58.2;U-937: 59.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066754 Enhanced NA NA 85000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" 5.2 1.7 0.7 12.2 0.8 16.0 2.8 1.2 1.0 3.1 1.8 5.0 6.0 2.6 0.9 1.8 1.9 5.8 0.8 0.8 0.8 1.6 3.7 8.3 26.9 1.8 0.7 0.9 0.4 0.2 0.7 1.0 1.2 2.1 5.9 0.1 2.7 1.1 0.4 1.0 10.1 1.4 0.7 12.8 6.8 0.8 1.2 61.8 3.9 0.1 20.2 11.8 2.6 2.2 0.1 0.0 0.2 0.1 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.3 1.6 0.3 0.3 0.0 0.0 0.7 0.1 0.1 0.0 0.2 0.0 15.9 0.2 0.2 0.0 0.8 1.3 0.0 0.0 0.1 0.1 1.2 0.0 18.2 0.3 2.0 0.0 0.0 68.7 0.2 0.6 0.0 0.0 0.1 1.9 0.5 0.6 58.2 0.1 0.0 0.2 0.9 0.1 0.3 0.3 0.2 0.0 0.3 1.1 0.3 0.1 5.6 1.9 0.0 0.3 59.0 12.2 2.3 0.5 15.6 74.0 0.3 117.2 10.8 67.0 85.3 0.3 18.8 68.7 81.8 2.7 79.5 0.7 0.5 47.4 46.4 0.7 0.8 1.2 1.0 0.8 0.8 1.8 0.7 1.2 0.7 1.2 2.2 1.5 19.2 19.0 0.0 12.5 3.2 0.8 0.1 1.2 1.6 1.6 1.4 1.0 0.0 9.3 1.8 0.0 0.6 96.8 0.8 0.0 0.1 0.8 2.1 0.8 3.0 0.0 9.3 0.7 0.0 0.2 4.3 8.6 1.6 16.4 0.4 2.2 0.9 0.2 0.0 0.4 0.7 0.0 5.0 6.7 1.1 0.3 6.7 3.6 6.5 2.9 0.5 58.7 0.0 0.1 0.0 1.3 0.0 29.6 0.3 0.0 0.4 1.7 2.1 0.0 0.8 1.0 0.4 0.7 0.6 3.1 1.9 199.9 0.2 0.5 0.6 CD99L2 "CD99B, MIC2L1" ENSG00000102181 "CD99 molecule like 2" Q8TCZ2 X 150766336-150898816 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 179.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.1;Horizontal cells: 52.2;Inhibitory neurons: 57.2;Oligodendrocytes: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038782, HPA038783, HPA061400" Enhanced Supported "Plasma membrane" NA NA 1200000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA038782: AB_10795139, HPA038783: AB_10794734, HPA061400: AB_2732660" "unprognostic (2.10e-2)" "unprognostic (2.62e-3)" "unprognostic (3.12e-3)" "unprognostic (6.03e-3)" "unprognostic (1.22e-1)" "unprognostic (2.66e-1)" "unprognostic (5.56e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.74e-5)" "unprognostic (5.50e-2)" "unprognostic (5.13e-2)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (9.23e-2)" "prognostic unfavorable (8.74e-4)" 46.1 28.1 68.5 14.8 69.5 7.3 29.7 71.0 99.6 33.4 26.8 40.1 10.0 39.9 24.5 14.5 30.5 19.2 61.6 69.9 80.4 24.9 47.3 25.2 13.2 104.7 77.9 38.9 18.7 14.6 23.8 21.5 107.2 25.8 10.6 43.4 14.8 32.6 179.1 13.4 19.2 32.4 71.5 26.9 21.8 11.2 91.6 14.5 16.8 99.2 10.7 29.4 21.0 80.2 8.1 79.8 29.5 36.9 153.3 95.2 8.7 65.2 76.1 32.3 46.3 5.5 10.2 29.3 154.0 114.6 24.2 13.0 40.4 44.4 26.6 68.5 31.9 12.7 17.8 8.2 41.2 21.4 23.3 90.3 14.5 24.0 45.4 50.3 38.6 22.4 8.9 74.9 41.1 17.3 18.9 31.1 12.4 6.9 42.7 18.8 24.2 40.5 31.7 5.4 38.9 19.9 25.8 21.9 29.6 21.6 6.2 36.6 45.8 47.5 14.4 62.2 48.0 62.6 112.3 28.3 59.6 42.3 36.4 7.3 8.6 5.9 6.2 7.6 5.4 4.5 5.8 6.3 8.1 4.8 5.5 6.0 2.1 7.2 12.5 5.8 4.4 7.0 68.5 69.5 71.0 99.6 69.9 80.4 104.7 77.9 107.2 71.5 91.6 80.2 14.1 16.0 7.8 21.5 8.2 3.1 2.3 3.6 4.6 26.8 3.7 3.2 42.8 11.5 6.4 12.9 18.8 10.1 7.4 2.0 5.9 4.4 0.3 5.6 10.1 13.8 8.4 6.5 49.1 5.3 3.9 15.9 7.1 3.6 7.6 12.6 17.2 26.6 10.2 52.2 57.2 2.9 8.2 16.4 6.8 2.8 20.8 8.6 10.6 23.4 8.1 18.2 2.1 21.6 60.7 3.6 3.1 30.1 12.5 3.4 5.3 11.3 5.0 18.7 0.0 15.9 12.0 2.8 4.9 3.3 1.3 13.5 6.4 11.8 3.3 1.3 CDC14B "Cdc14B1, Cdc14B2, CDC14B3, hCDC14B" ENSG00000081377 "Cell division cycle 14B" O60729 9 96490241-96619843 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3" "Cell type enhanced" "Detected in many" "Astrocytes: 86.5;Excitatory neurons: 83.5;Inhibitory neurons: 110.2;Oligodendrocyte precursor cells: 156.9;Oligodendrocytes: 273.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 10.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064747 Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA064747: AB_2732719" "unprognostic (5.69e-2)" "unprognostic (9.09e-2)" "unprognostic (3.50e-2)" "unprognostic (8.08e-3)" "unprognostic (4.24e-1)" "unprognostic (1.19e-2)" "unprognostic (1.11e-2)" "unprognostic (4.49e-2)" "unprognostic (1.63e-2)" "unprognostic (2.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.75e-1)" "prognostic favorable (2.97e-10)" "unprognostic (2.01e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (7.40e-2)" 4.3 2.3 11.1 1.1 15.8 3.0 3.0 6.1 11.7 2.9 1.4 3.1 2.8 1.3 2.0 1.4 4.2 2.9 5.0 5.2 6.9 5.5 10.3 3.0 0.9 11.0 12.1 3.4 4.6 6.9 1.1 2.0 11.4 3.3 3.3 1.7 1.8 4.1 0.7 0.8 3.3 1.7 10.4 0.8 6.1 9.3 11.4 2.9 8.5 1.4 1.2 4.1 0.8 27.3 7.4 4.1 4.2 4.4 20.2 30.1 11.6 5.3 7.0 3.5 5.6 14.0 11.6 0.0 5.0 11.3 8.4 8.1 6.1 4.0 4.1 1.9 5.8 1.1 1.5 11.2 3.3 0.0 0.2 12.4 2.1 3.7 3.4 4.0 0.7 0.0 4.4 0.8 4.8 3.5 0.0 1.2 7.9 8.4 3.6 0.0 2.6 0.2 5.4 11.3 1.3 6.6 3.7 1.1 2.0 14.2 0.9 2.3 2.2 3.5 4.1 9.0 3.9 0.1 0.0 0.0 3.7 0.0 8.3 10.4 0.0 2.2 2.0 0.0 1.0 1.1 0.8 1.5 0.0 0.4 1.4 0.9 0.0 0.1 0.0 0.0 1.1 0.6 11.1 15.8 6.1 11.7 5.2 6.9 11.0 12.1 11.4 10.4 11.4 27.3 4.0 6.4 8.8 86.5 3.7 9.1 8.9 4.4 9.1 7.2 8.4 6.1 17.9 11.5 11.4 9.2 8.4 6.4 2.3 7.1 7.9 5.5 36.9 27.4 7.5 6.2 2.4 0.4 83.5 6.5 3.0 17.3 21.4 33.9 14.5 2.9 6.8 31.2 11.3 8.4 110.2 9.0 8.2 1.6 6.7 33.3 9.0 5.5 8.8 56.2 2.4 12.8 2.1 156.9 273.9 8.6 7.3 11.7 8.3 10.8 16.9 17.0 15.7 12.4 26.3 18.6 15.7 10.8 7.3 4.7 7.7 3.4 4.4 1.2 8.6 13.2 CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358981-43363203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.9;lymphoid tissue: 52.6;testis: 49.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.0;Early spermatids: 135.0;Erythroid cells: 96.0;Extravillous trophoblasts: 146.2;Spermatocytes: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.2;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.5;NK-cell: 9.5;T-reg: 11.6" "Group enriched" "Detected in many" 9 "B-cells: 4.2;NK-cells: 9.5;T-cells: 11.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB004525, HPA045842, HPA055288" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB004525: AB_628089, HPA045842: AB_2679470, HPA055288: AB_2682773" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-2)" "unprognostic (2.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (4.00e-8)" "unprognostic (9.06e-3)" "unprognostic (1.17e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (8.55e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.29e-2)" 1.6 1.5 0.6 16.2 1.1 53.9 5.2 0.8 1.3 3.5 0.4 14.8 13.7 2.3 2.5 27.2 1.7 1.2 0.9 0.7 1.1 2.3 1.7 2.5 32.6 1.3 1.1 0.7 0.6 0.2 0.3 9.7 1.1 0.8 16.0 0.2 4.4 0.7 0.3 11.3 12.2 7.3 0.8 11.7 7.0 49.1 1.7 52.6 1.7 0.2 50.8 3.3 7.0 1.3 311.9 148.2 202.8 133.4 6.9 17.6 193.5 140.3 125.0 400.0 211.4 234.5 250.9 178.3 80.1 130.1 140.6 212.8 225.3 267.9 331.5 140.8 165.6 261.4 143.6 147.3 2.1 184.3 91.4 6.0 12.4 278.2 249.6 35.1 172.2 167.5 120.2 119.3 184.0 120.4 179.2 113.5 257.2 147.0 196.9 255.8 277.9 112.9 98.5 81.3 119.2 58.9 248.1 165.8 76.6 154.9 116.3 231.7 90.2 118.9 276.2 133.7 445.0 90.6 86.7 185.7 85.2 227.6 181.6 0.0 0.1 0.0 0.3 0.0 0.0 4.2 3.2 3.5 0.9 0.9 0.1 0.3 0.7 9.5 0.0 0.2 11.6 2.8 0.6 1.1 0.8 1.3 0.7 1.1 1.3 1.1 1.1 0.8 1.7 1.3 2.1 0.0 1.1 0.0 12.2 10.5 3.8 17.6 6.2 0.5 6.4 9.7 0.7 1.5 4.8 0.0 0.0 65.0 2.8 16.9 0.0 2.2 135.0 14.6 2.4 4.5 0.0 96.0 0.2 0.4 146.2 9.3 11.7 4.6 0.0 46.5 7.9 1.3 37.4 0.0 0.0 18.5 24.4 6.2 7.5 18.5 2.8 9.3 0.0 0.0 1.8 0.3 0.0 0.0 1.6 0.7 0.5 1.9 34.4 2.7 3.2 3.1 8.3 2.9 0.0 1.0 25.4 126.5 39.8 47.3 8.4 10.7 5.1 1.6 37.5 7.4 CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188417 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.3;lymphoid tissue: 8.8;testis: 13.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 111.2;Early spermatids: 18.3;Late spermatids: 31.8;Spermatogonia: 16.3" "Cancer enhanced" "Detected in many" "testis cancer: 19.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005855, HPA008803" Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "Golgi apparatus" "HPA005855: AB_1846364, HPA008803: " "unprognostic (1.49e-1)" "unprognostic (8.13e-2)" "unprognostic (1.20e-2)" "unprognostic (1.43e-3)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (7.05e-7)" "unprognostic (1.35e-2)" "unprognostic (4.32e-3)" "unprognostic (8.92e-3)" "unprognostic (4.41e-2)" "unprognostic (9.09e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-3)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" 0.7 0.9 0.8 3.3 0.8 15.3 1.1 0.7 1.0 0.6 0.7 3.5 2.0 0.6 0.9 2.4 0.2 0.3 0.4 0.8 2.0 0.7 0.8 0.3 4.4 1.1 1.9 2.2 0.7 0.8 0.8 2.6 1.7 0.6 3.9 2.0 0.8 0.6 0.4 0.6 1.8 1.1 0.8 2.0 0.9 13.3 2.0 8.8 1.8 0.3 5.6 0.9 0.9 0.7 22.2 10.7 50.0 27.2 1.7 3.2 34.2 29.9 11.3 36.7 29.6 46.8 11.2 64.9 11.4 8.0 23.4 16.3 86.6 20.6 38.6 21.4 45.1 83.8 19.0 23.1 1.7 59.4 23.4 1.7 3.1 45.8 19.6 4.6 14.1 47.8 67.6 33.6 20.1 11.8 74.8 46.6 73.4 20.2 24.2 33.2 32.9 35.1 9.5 20.7 23.5 28.8 18.6 21.6 9.5 31.7 11.3 41.9 7.2 18.0 27.7 20.3 41.4 16.7 54.2 101.5 13.5 65.2 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.0 0.8 2.0 1.1 1.9 1.7 0.8 2.0 0.7 0.3 0.0 0.0 1.0 1.1 0.4 0.4 0.8 1.8 0.5 1.2 1.0 111.2 0.0 0.1 0.0 2.1 4.2 0.2 2.4 0.0 0.4 18.3 0.5 0.9 2.7 1.2 8.0 0.2 0.9 7.4 1.5 1.5 1.3 0.0 4.6 1.4 0.3 3.1 0.0 0.5 2.0 0.0 0.6 0.9 31.8 1.5 0.5 0.0 0.0 0.1 1.1 0.0 0.5 0.0 1.1 0.8 1.9 13.0 0.7 0.4 0.4 0.2 0.4 0.0 0.1 2.2 14.5 16.3 4.3 0.0 0.3 0.6 2.4 4.1 0.5 CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285269-138338355 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.8;lymphoid tissue: 8.9;testis: 18.1" "Cell type enhanced" "Detected in many" "Early spermatids: 41.4;Late spermatids: 42.1;Spermatocytes: 53.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB003800, HPA066991" Approved Enhanced "Nuclear speckles" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB003800: AB_562081, HPA066991: AB_2685760" "unprognostic (2.45e-3)" "unprognostic (5.89e-3)" "prognostic favorable (2.49e-4)" "unprognostic (9.72e-3)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.03e-6)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-3)" "unprognostic (1.00e-1)" "unprognostic (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.43e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-1)" 0.2 0.2 0.2 2.1 0.2 5.8 0.7 0.3 0.3 0.3 0.2 3.4 3.0 0.4 0.2 1.4 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.3 3.2 0.2 0.3 0.0 0.4 0.1 0.1 1.2 0.2 0.2 4.1 0.1 0.3 0.1 0.0 1.4 3.0 0.8 0.1 0.9 1.1 18.1 0.2 8.9 0.1 0.0 4.6 0.5 0.5 0.2 27.9 11.0 38.4 28.9 0.9 3.6 9.9 16.4 17.5 36.2 50.3 27.3 52.8 13.3 13.8 10.1 40.5 14.9 31.7 25.9 34.9 11.1 21.5 9.6 15.0 21.2 0.3 6.3 10.0 0.8 0.9 22.0 18.0 3.8 24.6 28.9 14.8 24.2 22.9 15.5 19.3 16.7 9.7 22.3 12.2 11.9 34.2 15.0 6.4 8.4 19.2 11.9 36.8 11.0 16.9 32.6 18.7 13.9 7.2 19.9 16.8 13.9 26.5 15.0 13.4 13.0 8.3 14.3 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.1 0.2 0.2 0.1 0.0 0.0 1.3 0.9 0.6 0.3 1.1 1.8 0.0 0.9 0.8 0.3 0.0 0.2 0.0 0.0 5.0 0.5 1.8 0.0 0.1 41.4 0.4 0.9 0.6 0.0 9.5 1.3 0.0 6.9 1.1 3.6 1.2 0.0 5.5 1.4 0.4 2.7 0.0 1.0 3.9 2.0 0.6 0.5 42.1 1.8 1.2 0.0 1.0 0.6 0.0 0.0 1.0 0.3 0.0 1.4 0.4 4.5 0.3 0.9 0.1 0.1 0.0 0.0 0.2 0.9 53.6 13.0 4.3 0.4 1.4 0.6 0.2 4.9 0.6 CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370, HPA074334: " "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" 35.1 36.7 52.0 13.3 51.2 34.5 34.2 51.5 63.0 36.9 47.5 62.5 17.8 33.5 14.1 40.5 33.6 10.1 80.0 52.7 48.7 32.1 88.0 32.1 12.5 51.0 50.7 35.6 58.5 18.7 43.4 29.2 50.8 36.9 11.5 28.2 34.2 19.3 105.0 51.8 27.6 18.5 48.2 31.0 38.6 100.2 52.7 16.4 26.7 63.2 9.7 43.7 34.2 52.7 54.8 54.6 66.4 54.7 29.2 28.4 68.5 47.8 36.1 50.2 51.9 86.1 32.8 29.5 49.3 34.1 30.1 36.9 52.1 40.2 25.0 49.2 146.0 27.8 35.5 94.5 73.6 39.0 32.4 36.4 58.9 42.2 43.6 38.8 60.6 41.2 120.3 57.5 33.8 80.7 53.3 53.6 85.3 39.4 51.7 49.1 35.1 51.2 38.0 32.4 87.2 65.9 41.5 42.1 85.2 53.2 34.0 57.4 50.5 36.5 43.7 86.2 65.2 57.7 47.3 40.1 50.0 55.6 38.8 3.2 2.5 4.7 1.6 2.7 1.1 2.3 2.1 2.9 2.0 1.0 1.6 1.6 8.2 1.2 3.5 1.6 2.5 1.0 52.0 51.2 51.5 63.0 52.7 48.7 51.0 50.7 50.8 48.2 52.7 52.7 39.4 0.0 5.4 21.9 11.4 46.8 17.5 5.4 16.5 35.5 43.4 47.1 27.7 27.1 3.5 14.7 25.0 44.3 30.9 47.4 13.7 24.9 63.9 29.6 28.3 27.7 13.2 77.7 8.3 20.5 55.4 21.4 16.8 42.3 0.0 28.1 15.7 41.1 27.9 16.8 6.3 34.0 14.2 14.5 38.6 249.4 18.0 20.6 19.6 2.8 15.1 68.9 20.6 6.6 12.9 45.0 27.0 15.1 25.0 34.8 25.9 18.9 5.5 44.3 13.1 22.6 34.9 22.4 54.6 15.2 54.7 63.1 22.0 27.1 23.7 27.9 CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318474 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 320.3;Excitatory neurons: 447.6;Inhibitory neurons: 479.0;Oligodendrocyte precursor cells: 444.3;Oligodendrocytes: 671.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments" "CAB070414: AB_11156796, HPA071252: AB_2686374" "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" 15.6 12.5 26.3 5.5 32.4 3.5 12.2 33.5 30.0 15.8 12.2 21.2 14.7 15.0 7.7 10.1 12.6 13.7 16.4 24.9 25.2 17.3 14.7 12.3 2.0 25.7 26.8 14.0 13.1 19.7 14.6 12.7 27.0 15.8 10.3 23.7 7.6 14.9 11.4 6.3 12.9 14.5 19.8 6.6 22.4 24.4 29.7 2.2 8.1 13.6 1.8 23.0 11.3 37.0 22.6 21.1 21.9 10.4 21.5 26.4 7.7 25.4 35.7 17.2 17.9 17.1 50.1 0.1 26.6 42.4 13.0 10.3 16.3 14.2 20.9 0.1 13.2 17.4 25.5 6.7 24.3 14.1 7.5 18.6 17.9 27.8 27.8 21.3 58.0 13.6 45.1 0.1 28.2 6.2 0.4 2.5 18.0 29.3 20.0 0.0 37.0 0.1 27.7 43.1 15.7 22.9 43.0 17.8 24.8 13.4 23.1 0.8 59.0 31.3 16.2 36.1 33.9 0.1 0.1 0.1 41.4 0.0 42.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 26.3 32.4 33.5 30.0 24.9 25.2 25.7 26.8 27.0 19.8 29.7 37.0 82.6 41.7 35.7 320.3 0.8 11.7 26.0 15.9 12.0 97.7 14.0 12.8 59.9 30.0 38.9 44.1 118.9 5.9 1.8 49.3 13.7 26.0 128.0 18.7 45.1 68.4 26.4 45.6 447.6 41.1 7.3 44.4 92.8 25.7 7.0 21.5 47.8 28.9 3.7 223.8 479.0 30.5 22.4 4.4 9.9 132.3 44.1 6.4 16.0 180.8 5.9 33.4 0.0 444.3 671.8 65.1 74.0 85.4 1.8 30.1 50.7 41.3 24.8 66.9 78.9 64.0 68.4 45.6 57.7 8.0 8.0 1.4 1.3 23.4 34.4 43.1 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 CDC45 "CDC45L, CDC45L2" ENSG00000093009 "Cell division cycle 45" O75419 22 19479457-19520612 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;lymphoid tissue: 20.4;testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Erythroid cells: 29.7;Spermatocytes: 72.3;Spermatogonia: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "K-562: 370.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000614, CAB009459" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "CAB009459: AB_2078507, HPA000614: AB_1078487" "unprognostic (5.56e-2)" "unprognostic (6.12e-3)" "unprognostic (1.17e-3)" "unprognostic (3.42e-3)" "unprognostic (3.57e-1)" "unprognostic (7.42e-2)" "prognostic unfavorable (6.95e-6)" "unprognostic (6.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (8.94e-4)" "unprognostic (7.28e-2)" "unprognostic (0.00e+0)" "unprognostic (7.62e-3)" "unprognostic (2.02e-1)" "unprognostic (8.52e-2)" "unprognostic (1.10e-1)" 0.5 0.5 0.7 6.2 0.5 25.4 1.5 0.2 0.2 1.1 0.4 4.6 3.5 0.9 0.3 5.3 0.4 0.5 0.3 0.2 0.4 0.3 1.2 0.9 11.3 0.5 0.4 0.2 0.2 0.2 0.1 3.2 0.5 0.4 6.0 0.1 0.9 0.2 0.1 3.3 3.1 1.8 0.2 2.8 2.6 23.4 1.1 20.4 0.3 0.0 11.8 1.9 1.7 0.3 57.4 42.2 56.4 42.9 2.0 5.6 24.4 65.4 31.6 75.5 75.5 35.8 30.5 62.2 23.2 21.0 28.9 51.9 58.2 45.9 59.5 72.3 96.3 82.8 50.1 41.3 3.1 125.0 43.7 1.3 2.4 57.9 26.0 7.0 38.8 63.0 370.6 73.3 44.8 77.2 98.1 56.5 16.7 106.2 34.4 77.1 95.5 26.5 16.9 49.3 72.1 37.0 38.1 40.0 12.0 21.7 26.2 51.0 15.0 60.0 91.6 46.0 62.8 24.6 46.8 67.5 30.1 58.9 82.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.2 0.1 0.5 0.5 0.1 0.3 0.9 0.6 0.7 0.5 0.2 0.2 0.2 0.4 0.5 0.4 0.5 0.2 1.1 0.3 0.2 0.0 0.0 0.0 1.9 2.7 1.7 3.7 0.0 0.0 0.7 0.8 0.4 0.0 0.5 0.0 0.0 11.9 1.4 1.9 0.0 0.8 120.5 0.9 0.7 1.2 0.0 29.7 0.1 0.0 19.8 2.3 1.5 1.0 0.0 5.5 3.6 0.0 7.2 0.0 0.1 1.2 4.1 0.6 1.0 14.4 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.7 12.6 0.2 0.4 0.0 0.3 0.0 6.6 1.5 13.9 72.3 50.7 3.3 1.8 4.9 1.2 0.8 5.1 2.5 CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.2;lymphoid tissue: 17.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.2;Erythroid cells: 37.2;Extravillous trophoblasts: 34.6;Plasma cells: 31.6;Spermatocytes: 69.5;Spermatogonia: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Cell line enhanced" "Detected in all" "SK-BR-3: 500.3" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: AB_2681021, HPA065070: AB_2732729" "unprognostic (1.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.97e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (5.96e-8)" "unprognostic (2.31e-3)" "unprognostic (1.46e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (5.47e-2)" "unprognostic (3.00e-15)" "unprognostic (1.86e-2)" "unprognostic (1.35e-1)" "unprognostic (3.95e-3)" "unprognostic (3.88e-2)" 2.1 1.9 0.5 13.7 0.8 27.2 3.4 0.2 1.9 3.2 0.0 8.4 7.5 2.2 1.1 5.7 1.0 2.8 0.6 1.1 0.1 0.5 3.0 1.4 16.4 0.1 0.0 0.9 1.9 0.8 0.5 9.3 0.3 1.1 8.7 0.5 1.3 1.2 0.3 2.8 6.7 3.7 0.0 3.7 3.6 10.1 0.2 16.7 1.7 0.5 17.1 4.3 1.8 0.6 155.1 119.0 115.1 86.5 6.7 12.7 118.0 159.9 49.0 149.2 166.5 135.8 64.9 123.9 99.6 35.9 85.9 214.0 112.2 76.2 148.9 64.5 98.4 96.2 122.3 134.6 4.4 133.3 55.1 4.7 8.1 156.4 107.1 14.8 46.9 84.2 183.0 109.0 71.9 95.8 199.3 43.3 101.6 96.9 48.7 145.0 286.8 119.9 30.3 184.8 85.6 76.9 146.9 500.3 55.4 100.3 100.8 120.0 34.7 95.5 146.3 170.8 196.1 46.1 103.6 222.8 84.6 93.9 109.2 0.1 0.1 0.0 0.8 0.0 0.5 0.4 0.6 1.1 0.7 0.3 0.4 1.1 0.1 1.5 0.0 3.6 2.4 0.6 0.5 0.8 0.2 1.9 1.1 0.1 0.1 0.0 0.3 0.0 0.2 0.6 2.2 0.0 2.0 0.7 4.9 4.2 1.1 3.7 3.4 0.2 2.1 2.2 0.9 1.5 1.3 0.0 0.0 23.2 2.3 7.8 0.0 1.3 2.2 1.3 2.9 2.1 0.0 37.2 2.0 0.6 34.6 5.6 3.6 5.1 0.0 8.1 1.1 0.9 8.3 0.0 0.7 6.1 0.0 1.3 2.1 1.0 2.8 1.5 0.0 0.0 0.0 0.4 2.1 0.0 0.2 1.5 3.0 0.7 31.6 1.3 0.8 0.2 0.2 0.3 13.1 0.6 4.6 69.5 57.2 9.1 1.6 16.7 3.3 1.9 9.3 2.4 CDCA2 "PPP1R81, Repo-Man" ENSG00000184661 "Cell division cycle associated 2" Q69YH5 8 25459199-25507911 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.5;lymphoid tissue: 11.4;testis: 19.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 23.3;Early spermatids: 49.9;Erythroid cells: 19.0;Late spermatids: 24.2;Spermatocytes: 66.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA026293, HPA030049" Enhanced Supported Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA026293: AB_1846384, HPA030049: AB_10600862" "unprognostic (2.12e-1)" "unprognostic (4.75e-3)" "prognostic favorable (9.62e-4)" "unprognostic (2.92e-2)" "unprognostic (9.69e-2)" "unprognostic (3.56e-2)" "unprognostic (2.50e-5)" "unprognostic (1.47e-3)" "unprognostic (6.06e-2)" "unprognostic (2.91e-3)" "unprognostic (1.32e-3)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.30e-14)" "unprognostic (1.36e-2)" "unprognostic (4.02e-1)" "unprognostic (1.91e-1)" "unprognostic (5.30e-2)" 0.2 0.0 0.0 2.6 0.0 6.5 0.6 0.1 0.0 0.2 0.1 1.9 1.6 0.3 0.0 1.4 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.2 5.3 0.2 0.2 0.0 0.0 0.0 0.0 1.2 0.2 0.1 2.2 0.1 0.2 0.0 0.0 1.1 1.8 0.8 0.0 0.8 0.9 19.4 0.3 11.4 0.1 0.1 6.7 0.6 0.3 0.1 36.5 30.2 29.4 24.2 2.3 4.5 20.2 37.7 22.6 32.9 32.4 25.7 15.8 42.6 16.0 16.2 34.6 31.6 42.9 20.0 48.5 16.2 12.0 43.2 22.4 15.2 0.6 18.4 19.4 2.5 1.0 23.5 15.8 3.3 24.5 24.5 33.6 45.8 30.6 13.9 54.5 8.7 31.0 24.1 14.5 26.3 33.4 15.2 9.2 18.7 12.0 13.3 33.3 16.1 14.3 14.7 17.4 9.4 16.6 23.9 39.3 44.7 35.6 7.1 16.5 44.4 17.7 24.3 40.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.3 0.1 0.2 0.0 1.1 0.0 2.7 1.1 0.5 1.7 0.0 0.7 0.9 0.8 23.3 0.0 0.2 0.0 0.0 7.2 0.5 1.8 0.0 0.2 49.9 0.8 1.2 1.1 0.0 19.0 0.2 0.0 13.4 2.5 4.1 1.4 0.0 8.8 1.1 0.1 4.1 0.0 0.1 1.3 0.0 2.9 0.6 24.2 1.2 2.1 0.0 0.0 0.6 0.1 2.1 0.5 0.6 0.2 0.1 0.0 15.8 0.5 0.5 1.2 0.9 0.5 13.1 0.1 2.1 66.6 27.8 10.7 0.9 1.6 2.9 1.3 3.6 0.5 CDCA3 "GRCC8, TOME-1" ENSG00000111665 "Cell division cycle associated 3" Q99618 12 6844793-6851292 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.5;retina: 66.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Erythroid cells: 46.5;Extravillous trophoblasts: 74.1;Proximal enterocytes: 65.5;Spermatocytes: 71.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA026587 Approved Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA026587: AB_1846386" "unprognostic (3.05e-1)" "unprognostic (1.32e-1)" "unprognostic (9.85e-2)" "unprognostic (1.63e-2)" "unprognostic (2.42e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.51e-5)" "prognostic unfavorable (9.77e-5)" "unprognostic (3.88e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-3)" "unprognostic (8.81e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.11e-1)" "unprognostic (4.94e-2)" 1.2 2.6 0.7 7.3 0.5 16.0 1.2 1.0 1.0 4.4 0.3 6.1 20.7 2.9 0.4 9.0 1.9 1.1 2.8 0.6 0.6 1.6 1.6 1.7 17.2 0.7 0.7 4.6 1.1 0.4 8.6 4.7 0.6 3.1 7.8 66.3 2.5 0.3 0.5 6.3 18.5 3.0 0.4 4.6 3.2 21.4 0.6 30.5 1.8 0.2 23.4 2.2 4.0 0.5 106.8 88.8 81.0 45.1 4.3 6.8 95.0 71.7 46.4 119.5 83.3 142.7 86.9 64.9 8.6 54.9 86.9 71.0 53.3 55.0 117.0 97.2 60.9 56.8 58.9 81.7 0.5 41.3 47.2 3.1 3.9 63.0 34.6 27.9 50.9 44.2 47.8 36.4 116.7 94.1 60.0 46.0 86.2 75.8 62.3 57.6 68.5 34.3 40.2 36.4 12.2 23.6 61.8 53.5 18.7 87.0 21.9 38.6 22.3 52.6 67.2 35.0 117.2 19.7 21.5 104.2 25.4 53.6 92.0 0.0 0.2 0.0 0.1 0.1 0.3 0.7 0.7 0.8 0.2 0.2 0.2 0.4 0.2 0.4 0.3 1.1 4.3 0.5 0.7 0.5 1.0 1.0 0.6 0.6 0.7 0.7 0.6 0.4 0.6 0.5 0.7 0.0 0.5 0.7 4.1 2.9 1.7 5.0 2.2 12.3 1.9 2.5 1.2 1.5 1.1 0.0 56.3 29.5 0.9 6.9 0.0 1.1 12.4 1.8 2.3 1.7 1.2 46.5 0.5 0.4 74.1 5.2 4.6 2.3 4.5 15.2 3.9 1.6 19.3 6.7 0.6 11.9 4.1 4.0 3.1 6.8 1.8 3.5 0.0 1.0 1.1 1.1 1.0 0.5 0.5 0.4 4.0 0.4 19.2 1.4 65.5 0.9 0.4 18.0 6.6 0.5 8.3 71.5 14.8 12.6 1.8 8.5 4.6 1.4 17.4 2.6 CDCA4 "FLJ20764, Hepp" ENSG00000170779 "Cell division cycle associated 4" Q9BXL8 14 105009573-105021083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 55.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 64.2;Cytotrophoblasts: 84.5;Extravillous trophoblasts: 154.5;Spermatogonia: 69.9;Suprabasal keratinocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA064971 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA064971: AB_2685395" "unprognostic (2.22e-3)" "unprognostic (1.84e-1)" "unprognostic (2.69e-1)" "unprognostic (9.93e-3)" "unprognostic (1.42e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (4.19e-4)" "prognostic unfavorable (7.94e-4)" "unprognostic (4.20e-2)" "unprognostic (8.54e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (2.15e-1)" "unprognostic (1.55e-1)" "unprognostic (7.50e-2)" "unprognostic (1.24e-2)" 3.9 2.6 1.9 7.4 2.0 55.8 4.2 3.0 2.1 8.7 2.1 4.6 4.7 5.4 1.8 18.6 4.1 2.6 2.7 1.7 1.8 3.4 2.7 3.6 11.6 2.1 1.9 4.1 3.2 1.8 1.7 9.2 2.1 3.8 2.9 1.3 5.5 2.2 1.4 24.7 4.9 3.5 1.9 6.6 3.8 11.6 2.0 14.6 3.3 1.5 8.5 4.2 10.2 2.0 40.6 41.3 46.7 35.6 7.9 13.2 61.1 59.0 18.0 45.2 39.7 50.9 50.2 52.9 31.5 20.9 34.5 63.5 32.9 68.0 27.1 58.2 26.1 33.4 33.9 43.2 9.7 59.8 27.0 9.4 20.8 35.2 32.7 15.1 31.4 45.0 37.5 53.0 32.1 98.8 56.2 40.1 34.8 35.1 94.0 53.6 68.1 19.7 15.9 46.2 27.2 33.5 56.6 22.3 46.8 20.5 44.0 39.8 48.8 39.9 50.5 55.3 79.5 19.5 25.9 54.4 33.5 30.2 67.5 1.1 4.3 10.6 11.9 4.9 14.8 8.4 12.7 16.7 4.7 5.4 7.4 8.9 1.6 12.9 5.6 5.1 11.1 7.0 1.9 2.0 3.0 2.1 1.7 1.8 2.1 1.9 2.1 1.9 2.0 2.0 5.4 0.0 2.2 0.7 7.4 64.2 26.5 36.6 13.1 3.4 8.7 8.3 0.6 0.0 9.0 1.8 0.0 84.5 11.5 4.3 3.9 12.7 8.1 9.0 9.0 10.9 3.0 53.0 1.8 7.0 154.5 10.2 3.1 12.5 28.6 15.1 7.9 2.2 24.3 13.5 1.3 6.6 6.1 5.9 22.6 6.8 8.4 8.4 17.8 2.8 9.3 4.6 9.2 1.0 1.8 12.3 3.3 6.0 11.8 16.1 1.9 1.8 7.7 2.6 6.6 4.6 12.5 43.0 69.9 21.3 67.1 25.9 17.7 3.6 9.5 43.2 CDCA5 ENSG00000146670 "Cell division cycle associated 5" Q96FF9 11 65066300-65084164 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.4;lymphoid tissue: 27.6;testis: 37.8" "Cell type enhanced" "Detected in many" "Early spermatids: 56.5;Extravillous trophoblasts: 38.3;Late spermatids: 116.9;Spermatocytes: 50.4;Spermatogonia: 31.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "NK-cell: 2.8;T-reg: 2.0" "Group enriched" "Detected in many" 5 "NK-cells: 2.8;T-cells: 2.0" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" "HPA023691, HPA076007" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA023691: AB_1846392, HPA076007: " "unprognostic (3.14e-2)" "unprognostic (4.20e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.15e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.21e-6)" "unprognostic (1.41e-3)" "unprognostic (7.55e-3)" "unprognostic (6.93e-2)" "prognostic unfavorable (8.72e-6)" "unprognostic (2.16e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.55e-3)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (8.97e-2)" 1.4 1.2 1.3 10.5 1.3 53.4 2.0 0.8 1.8 1.9 0.9 6.8 5.8 1.3 0.3 9.3 0.9 0.9 0.9 1.5 0.9 0.9 1.3 1.9 17.0 1.6 1.3 0.6 0.7 0.4 0.5 6.5 1.6 0.8 7.7 0.5 1.4 0.5 0.6 4.2 5.8 3.1 0.8 6.6 3.1 37.8 1.8 27.6 0.6 0.4 16.2 2.2 2.8 1.3 131.7 74.9 67.2 57.3 4.5 7.3 57.8 92.7 37.4 103.6 81.5 77.7 75.4 121.3 52.3 29.4 120.8 87.9 110.3 49.5 98.6 122.0 52.2 107.7 54.4 64.1 0.4 116.8 81.8 2.5 4.5 96.3 44.0 10.8 32.6 138.4 126.6 206.6 63.5 109.2 164.7 116.9 107.8 63.0 92.4 140.4 76.8 111.9 21.2 49.6 89.1 68.4 59.3 80.7 62.8 41.6 104.7 54.7 19.9 92.7 97.2 99.5 101.7 106.9 187.8 195.4 37.2 69.5 97.4 0.0 0.1 0.2 0.4 0.0 0.0 0.3 0.5 0.3 0.4 0.5 0.0 0.3 0.0 2.8 0.3 0.3 2.0 0.7 1.3 1.3 0.8 1.8 1.5 0.9 1.6 1.3 1.6 0.8 1.8 1.3 0.9 0.0 0.5 0.0 4.6 3.8 1.2 1.3 0.6 0.6 2.3 4.4 1.0 0.0 0.8 0.0 2.1 19.7 2.2 4.6 1.9 0.8 56.5 1.1 1.5 2.3 0.0 21.8 1.1 0.8 38.3 3.5 3.1 1.5 3.8 14.5 1.1 0.0 11.7 1.7 0.6 4.7 2.0 2.8 1.5 116.9 2.8 1.7 0.0 1.0 2.1 0.9 2.1 0.0 0.6 0.6 0.1 1.5 16.2 1.1 1.1 0.6 0.4 0.2 0.0 0.5 2.7 50.4 31.1 7.1 1.0 3.7 4.2 1.9 9.4 1.6 CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;lymphoid tissue: 38.8;testis: 22.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 34.1;Extravillous trophoblasts: 26.0;Spermatocytes: 76.8;Spermatogonia: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: AB_10670556, HPA028258: AB_10669864, HPA028783: AB_10671092" "unprognostic (8.36e-2)" "unprognostic (2.00e-1)" "unprognostic (8.39e-2)" "unprognostic (7.75e-3)" "unprognostic (2.34e-1)" "unprognostic (5.42e-2)" "prognostic unfavorable (4.93e-10)" "unprognostic (4.30e-3)" "prognostic unfavorable (6.04e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.32e-4)" "unprognostic (3.78e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (6.39e-3)" "unprognostic (2.99e-1)" "unprognostic (3.18e-1)" "unprognostic (1.67e-1)" 1.0 1.1 0.7 7.9 1.0 33.5 2.0 0.2 0.9 1.7 0.0 9.4 8.3 1.3 1.8 9.2 1.0 1.1 0.6 0.5 0.4 0.8 1.3 1.5 19.5 0.6 0.4 0.6 0.8 0.5 0.6 4.4 0.5 0.7 11.3 1.9 1.8 0.5 0.3 6.3 7.3 2.8 0.3 4.9 4.9 22.5 0.6 38.8 0.6 0.5 22.7 2.0 2.9 0.7 108.5 45.5 84.4 62.1 3.6 7.0 57.2 79.6 39.5 137.2 96.6 71.9 78.8 130.2 31.5 50.5 54.5 59.4 97.8 52.4 141.9 86.8 44.9 116.8 49.2 57.3 0.8 113.8 58.4 2.8 3.8 77.1 67.3 15.3 60.9 91.1 100.7 135.6 99.1 47.7 106.1 68.9 98.8 61.7 62.8 102.2 115.6 74.4 31.0 43.8 75.4 33.3 87.5 40.6 52.4 71.7 60.1 42.4 37.3 67.8 70.6 39.2 126.0 91.4 128.1 176.3 31.6 104.7 79.6 0.0 0.7 1.3 1.5 1.6 2.8 1.7 3.6 2.2 0.7 1.4 1.1 2.3 3.0 4.1 3.9 1.2 5.9 1.7 0.7 1.0 0.2 0.9 0.5 0.4 0.6 0.4 0.5 0.3 0.6 0.7 0.8 0.0 0.5 1.3 4.8 3.3 0.8 2.4 1.8 1.3 1.9 1.5 0.7 2.8 0.4 0.0 0.0 17.1 1.9 12.4 0.0 1.2 1.0 1.7 1.6 1.9 3.6 34.1 1.2 0.6 26.0 2.9 6.6 2.5 0.0 12.0 3.6 1.0 11.6 1.7 0.9 8.2 2.0 3.5 1.9 2.8 1.5 3.7 1.8 0.0 1.6 0.1 2.1 0.5 0.9 2.4 4.0 1.2 15.8 1.3 1.9 0.6 4.7 1.0 19.7 0.2 6.3 76.8 42.0 17.1 2.7 2.9 5.5 1.2 13.2 1.2 CDCP1 "CD318, SIMA135" ENSG00000163814 "CUB domain containing protein 1" Q9H5V8 3 45082277-45146422 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal respiratory cells: 92.6;Pancreatic endocrine cells: 137.1;Urothelial cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.3;NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 94.9;HBEC3-KT: 109.0;hTEC/SVTERT24-B: 265.2;hTERT-HME1: 177.9;PC-3: 89.7;RPTEC TERT1: 81.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010978, HPA010979, CAB025637" Enhanced "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB025637: , HPA010978: AB_1846403, HPA010979: AB_1846401" "unprognostic (9.31e-2)" "unprognostic (4.50e-2)" "unprognostic (1.67e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (1.41e-5)" "unprognostic (2.15e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (9.98e-3)" "unprognostic (3.59e-2)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" 2.3 0.5 0.4 4.4 0.7 0.9 5.6 0.4 1.2 8.5 12.8 17.4 17.7 3.2 9.2 37.2 4.0 6.2 0.5 0.7 0.7 4.8 0.8 8.2 0.8 1.4 0.8 0.3 7.9 1.4 1.2 2.2 1.3 5.1 17.0 0.2 12.6 5.6 0.3 23.3 15.1 3.1 1.1 0.7 16.5 0.6 3.6 0.6 7.7 0.0 5.8 9.7 16.4 2.6 52.2 15.1 0.0 0.2 0.1 2.4 12.1 9.7 1.6 4.4 4.1 21.3 94.9 0.0 11.8 2.9 2.5 40.5 0.3 109.0 8.9 0.0 0.1 0.1 16.4 0.1 8.1 0.1 3.6 3.7 56.1 265.2 177.9 16.0 1.0 0.1 31.1 0.2 13.8 0.1 0.1 0.9 7.4 24.7 89.7 0.0 0.0 8.6 81.1 40.7 3.4 0.1 20.1 5.0 0.1 4.8 22.9 0.4 4.6 0.2 0.2 3.3 0.2 0.1 0.1 0.1 1.5 1.1 1.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.1 0.0 0.9 4.2 0.0 0.0 0.0 0.2 0.4 0.7 0.4 1.2 0.7 0.7 1.4 0.8 1.3 1.1 3.6 2.6 0.1 3.2 13.1 0.3 0.3 121.2 83.3 92.6 50.7 0.0 12.9 6.6 0.5 14.3 57.7 9.2 0.0 5.8 0.3 76.6 0.0 78.6 0.1 36.5 6.3 1.9 37.6 0.4 2.0 71.6 7.5 4.6 37.8 59.3 8.8 0.1 0.0 0.0 10.8 0.0 0.4 37.9 18.3 7.9 37.6 0.5 3.1 13.4 3.6 0.0 10.7 0.0 0.0 1.0 0.3 137.1 34.9 0.0 2.5 75.8 30.8 0.0 56.6 0.0 0.0 0.4 3.6 0.0 0.4 59.8 75.0 3.3 1.8 13.5 28.9 117.4 CDHR1 "CORD15, KIAA1775, PCDH21, RP65" ENSG00000148600 "Cadherin related family member 1" Q96JP9 10 84194537-84219621 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 313.8;skin 1: 214.0" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 379.5;Rod photoreceptor cells: 240.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "NK-cell: 7.5" "Lineage enriched" "Detected in single" 12 "NK-cells: 7.5" "Cell line enhanced" "Detected in some" "HAP1: 10.2;HEK 293: 5.2;HEL: 6.3;K-562: 4.6;NTERA-2: 4.4;RPTEC TERT1: 16.3" "Region enriched" "Detected in many" 21 "olfactory bulb: 333.0" "Low region specificity" "Detected in all" HPA036819 Enhanced "Intracellular and membrane" NA NA 55000 "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA036819: AB_10671750" "unprognostic (8.91e-4)" "unprognostic (5.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.71e-2)" "unprognostic (2.63e-2)" "unprognostic (3.03e-2)" "unprognostic (6.40e-2)" "unprognostic (7.77e-2)" "unprognostic (1.41e-1)" "unprognostic (2.67e-1)" "unprognostic (6.69e-4)" "unprognostic (1.90e-1)" "unprognostic (5.51e-3)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (4.56e-3)" "unprognostic (5.07e-2)" 0.2 1.9 7.4 1.0 18.3 0.4 4.5 2.3 8.7 5.3 46.2 29.2 0.1 0.6 4.4 10.7 0.5 0.4 1.2 6.6 7.5 0.4 0.5 0.2 0.9 13.4 2.3 1.1 0.1 0.0 3.0 0.2 13.9 1.4 53.2 313.8 1.5 4.2 1.0 214.0 12.2 1.2 0.1 7.0 0.2 0.3 3.2 3.3 0.2 0.0 1.1 0.1 3.5 3.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 10.2 2.0 0.0 0.0 5.2 6.3 0.0 0.0 0.2 0.0 0.2 0.0 2.2 0.0 0.7 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.5 4.4 0.0 0.0 0.0 0.0 1.4 16.3 0.0 3.4 0.8 0.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.1 7.4 18.3 2.3 8.7 6.6 7.5 13.4 2.3 13.9 0.1 3.2 3.5 0.0 0.0 0.5 1.3 0.1 51.2 0.3 1.4 3.4 24.1 0.0 0.1 1.8 0.0 0.7 0.0 379.5 0.0 2.1 47.9 0.0 0.1 0.0 2.7 0.7 1.8 12.7 0.0 4.9 0.0 0.0 0.6 0.0 3.1 0.0 3.7 0.4 0.4 0.0 5.0 7.7 46.9 0.0 0.3 5.2 0.2 0.0 0.1 3.6 1.0 0.0 26.3 1.0 7.5 4.4 0.0 31.2 0.0 0.7 0.3 23.0 0.2 0.1 240.4 0.0 0.2 0.3 0.6 0.3 3.0 67.5 0.0 3.0 0.3 52.9 0.2 CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.2;lymphoid tissue: 74.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.9;Erythroid cells: 209.6;Extravillous trophoblasts: 144.6;Spermatocytes: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 3.2;T-reg: 3.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003387, CAB003799, CAB079974" Enhanced Supported Nucleoplasm,Cytosol NA Yes 51000 "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "CAB003799: AB_344898, CAB079974: , HPA003387: AB_1846356" "unprognostic (6.34e-2)" "prognostic favorable (8.81e-4)" "unprognostic (1.90e-1)" "unprognostic (6.82e-2)" "unprognostic (6.67e-2)" "unprognostic (3.83e-2)" "prognostic unfavorable (1.10e-6)" "prognostic unfavorable (7.88e-4)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.80e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.27e-1)" "unprognostic (2.75e-1)" "unprognostic (2.13e-1)" "unprognostic (1.60e-1)" 3.8 1.8 0.9 17.0 1.0 53.2 7.4 0.9 1.5 5.2 0.9 17.6 16.3 7.1 12.2 17.5 3.7 4.3 1.4 0.9 1.0 3.1 3.2 4.7 40.6 1.2 1.2 2.3 0.8 2.5 4.1 19.4 1.1 1.7 20.8 1.3 3.2 5.2 1.4 13.2 14.5 8.0 0.9 9.0 10.1 25.1 1.4 74.0 3.6 2.2 47.5 7.1 6.9 1.0 249.9 93.5 241.1 96.0 15.4 23.6 99.0 183.8 132.7 218.8 209.0 218.9 213.7 226.2 69.6 50.6 79.6 149.9 166.2 106.8 225.8 162.3 121.1 119.4 84.4 128.1 2.8 184.5 117.6 4.7 10.4 142.1 137.0 49.6 133.3 146.2 185.1 270.3 246.9 66.3 234.0 131.1 106.6 149.3 193.1 199.7 224.5 111.3 84.3 81.4 112.7 98.7 123.5 184.9 96.3 130.0 199.9 111.5 55.4 92.8 197.9 99.1 255.8 104.9 180.8 205.6 79.9 203.5 117.6 0.0 0.0 0.0 0.3 0.1 0.2 0.5 0.7 1.3 0.3 0.4 0.2 0.7 0.0 3.2 0.1 0.9 3.4 0.9 0.9 1.0 0.9 1.5 0.9 1.0 1.2 1.2 1.1 0.9 1.4 1.0 7.7 0.0 3.2 0.3 7.1 39.8 5.4 29.9 2.8 1.1 5.3 6.1 0.8 0.0 10.2 18.4 0.0 80.9 3.6 8.9 3.9 0.8 18.7 10.8 6.2 10.5 3.0 209.6 0.4 0.0 144.6 13.3 13.3 9.4 0.0 51.5 7.5 1.3 57.2 0.0 0.2 14.6 30.5 20.5 18.1 10.4 2.1 16.5 1.8 1.9 1.0 1.0 3.1 0.0 0.1 0.4 0.7 0.7 32.1 4.3 2.2 3.0 17.6 0.7 0.0 0.5 24.6 110.0 39.6 33.8 18.6 22.0 10.3 2.1 26.6 10.4 CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 15.2;ovary: 6.1" "Group enriched" "Detected in some" 13 "Early spermatids: 27.1;granulocytes: 79.1;Late spermatids: 40.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "Group enriched" "Detected in some" 28 "basophil: 1.8;eosinophil: 3.7" "Lineage enriched" "Detected in single" 37 "granulocytes: 3.7" "Cell line enhanced" "Detected in some" "BJ hTERT+: 22.6;BJ hTERT+ SV40 Large T+ RasG12V: 20.7;HBF TERT88: 30.9;HMC-1: 58.4;LHCN-M2: 19.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "Golgi apparatus" "HPA015786: AB_1844780" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.80e-2)" "unprognostic (7.38e-2)" "unprognostic (9.99e-5)" "unprognostic (6.31e-2)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" 0.7 0.3 0.0 0.2 0.0 0.0 0.8 2.4 0.4 0.8 0.0 0.5 0.3 0.6 15.2 0.6 0.5 1.9 0.2 0.5 0.0 0.3 0.0 1.0 0.1 0.4 0.1 6.1 0.1 0.2 0.3 0.0 0.4 0.7 0.7 0.0 0.3 0.3 0.9 0.6 0.8 0.4 0.1 0.0 0.7 1.9 0.1 0.2 0.1 0.7 0.1 0.8 0.5 0.3 0.3 0.0 0.0 0.0 1.6 2.8 0.0 5.9 22.6 10.2 20.7 0.0 3.0 0.0 0.0 2.3 0.5 0.0 0.0 0.0 30.9 0.0 0.1 1.9 0.0 0.0 0.3 0.1 58.4 3.4 0.0 2.7 1.5 0.4 0.0 0.0 0.0 0.1 19.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.5 2.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.4 0.5 0.0 0.4 0.1 0.4 0.1 0.1 0.3 0.1 0.0 1.3 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.8 0.0 0.0 79.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 40.3 0.3 0.1 3.6 1.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.5 0.2 0.0 0.1 0.0 0.9 0.1 0.0 0.0 CDKL2 "KKIAMRE, P56" ENSG00000138769 "Cyclin dependent kinase like 2" Q92772 4 75576496-75630716 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.3;choroid plexus: 8.6;retina: 9.6;testis: 11.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 76.4;Early spermatids: 57.8;Excitatory neurons: 32.8;Inhibitory neurons: 40.9;Oligodendrocytes: 46.4;Spermatocytes: 101.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.1;HHSteC: 1.9;RPTEC TERT1: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040672 Approved Nucleoplasm,Centrosome NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA040672: AB_10794744" "unprognostic (2.07e-1)" "unprognostic (9.96e-2)" "unprognostic (6.91e-2)" "unprognostic (3.80e-5)" "unprognostic (3.43e-2)" "unprognostic (2.71e-2)" "unprognostic (1.59e-1)" "unprognostic (8.14e-3)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.88e-15)" "unprognostic (5.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-1)" "unprognostic (7.52e-2)" 0.1 1.0 6.3 0.3 6.7 0.0 0.3 4.1 8.3 0.6 8.6 0.7 0.1 0.6 0.9 0.8 1.6 0.4 0.3 6.5 6.1 5.9 0.0 4.7 0.3 6.0 4.8 1.6 0.5 2.5 1.5 0.0 6.5 0.6 0.9 9.6 0.3 0.6 0.0 0.2 0.1 0.4 4.9 0.1 0.6 11.6 5.8 0.0 3.1 0.0 0.6 0.2 0.3 8.3 2.1 0.3 0.1 0.0 0.1 0.1 0.0 0.1 0.8 1.0 0.9 0.1 0.5 0.0 0.3 0.0 1.0 0.2 0.0 0.2 0.9 0.1 1.5 0.0 0.1 0.0 1.9 0.0 0.0 0.6 1.0 0.1 0.3 0.9 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.2 0.1 1.1 0.9 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 6.7 4.1 8.3 6.5 6.1 6.0 4.8 6.5 4.9 5.8 8.3 0.2 25.6 76.4 5.9 0.4 0.1 0.5 0.6 0.6 17.7 0.7 3.0 0.9 1.5 4.7 9.2 4.2 0.1 0.3 3.0 7.9 1.9 57.8 11.6 1.4 0.2 1.8 0.0 32.8 0.2 0.6 1.2 1.1 2.5 1.3 1.0 0.4 0.0 0.1 10.1 40.9 2.3 0.0 0.0 0.4 20.7 1.8 0.5 1.8 3.7 0.0 11.6 0.0 5.5 46.4 0.1 1.0 1.2 0.3 0.2 0.0 29.5 18.6 20.2 0.0 0.4 1.1 101.7 4.1 0.8 0.3 0.3 2.7 0.2 2.7 0.2 CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967752-21995301 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7;pituitary gland: 33.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 170.1;Club cells: 145.9;Early spermatids: 227.5;Late spermatids: 447.9;Pancreatic endocrine cells: 417.7;Respiratory ciliated cells: 221.9" "Cancer enhanced" "Detected in all" "cervical cancer: 49.9;ovarian cancer: 57.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 37.4" "Group enriched" "Detected in many" 6 "B-cells: 15.6;T-cells: 37.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 289.2;HEK 293: 389.7;HeLa: 311.1;SK-MEL-30: 318.7" "Low region specificity" "Detected in some" "CAB000093, CAB000445, CAB018232, HPA047838" Enhanced Supported Nucleoli NA NA 18000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoli "CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA047838: AB_2680174" "unprognostic (3.41e-2)" "unprognostic (4.51e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (1.82e-7)" "unprognostic (5.22e-2)" "prognostic favorable (5.19e-4)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.41e-2)" "unprognostic (1.22e-2)" "unprognostic (3.05e-2)" "unprognostic (3.55e-1)" 3.7 10.1 7.4 1.7 8.3 1.3 3.1 5.9 8.5 1.1 31.7 1.9 0.8 0.7 1.0 7.4 2.2 0.5 0.7 6.7 6.4 0.5 0.7 2.3 2.1 7.4 5.8 0.8 1.5 2.1 33.7 2.6 7.2 2.1 0.7 0.1 1.6 1.6 0.6 0.9 3.6 0.3 6.2 5.5 3.9 14.8 8.0 2.1 1.3 0.0 2.5 2.4 2.3 9.2 11.8 0.0 1.7 82.2 0.8 0.9 39.1 15.9 0.0 111.7 196.0 19.1 289.2 47.1 167.7 9.5 0.0 36.0 34.3 211.0 91.4 212.2 389.7 0.1 311.1 13.6 8.8 22.4 17.3 21.2 0.0 112.2 61.9 236.3 11.7 0.0 0.1 188.4 105.7 0.8 1.9 0.0 2.6 24.2 185.9 0.2 80.2 166.3 23.4 0.0 195.2 14.0 219.9 36.6 318.7 9.4 42.8 0.7 39.5 0.9 2.6 0.3 0.5 84.7 49.6 177.8 0.2 62.9 1.0 1.5 2.1 0.3 9.9 1.3 14.1 11.1 11.4 17.6 0.3 15.6 0.6 6.7 0.5 0.8 4.2 0.0 37.4 3.6 7.4 8.3 5.9 8.5 6.7 6.4 7.4 5.8 7.2 6.2 8.0 9.2 1.6 0.0 0.0 1.0 11.5 1.8 2.3 170.1 0.0 0.6 6.1 10.4 4.2 0.0 145.9 11.0 0.0 27.9 6.2 8.1 0.0 29.7 227.5 36.4 6.7 2.6 70.9 0.0 1.2 26.4 43.8 7.7 0.0 6.2 4.5 4.6 1.4 0.3 7.6 0.0 3.5 6.3 122.1 10.5 4.2 447.9 3.1 2.9 8.8 7.5 16.2 0.9 5.2 4.5 6.6 417.7 12.1 1.9 38.7 35.4 32.8 0.0 221.9 0.1 0.0 1.1 20.8 7.2 6.2 7.2 0.4 9.2 12.7 11.0 3.8 54.4 CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.2;intestine: 30.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 240.7;Pancreatic endocrine cells: 164.5;Proximal enterocytes: 139.0;Squamous epithelial cells: 142.0;Urothelial cells: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 38.1;HaCaT: 35.0;HeLa: 33.9;hTERT-RPE1: 60.1;SiHa: 48.0;SK-MEL-30: 35.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000349, HPA052838, HPA063327" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB000349: , HPA052838: , HPA063327: AB_2684987" "unprognostic (2.30e-1)" "unprognostic (9.23e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.47e-6)" "unprognostic (2.10e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.01e-1)" "unprognostic (3.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (9.14e-3)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.28e-2)" 18.7 1.9 2.0 2.9 1.8 0.4 8.6 1.1 1.9 9.6 9.1 22.4 21.7 3.8 0.6 36.2 1.7 2.4 1.0 1.6 2.2 1.2 1.2 12.6 1.1 2.7 1.5 0.9 1.2 3.3 3.5 2.3 2.3 3.6 19.7 2.8 6.7 4.7 7.2 12.9 30.9 2.1 1.7 4.6 6.0 5.3 2.4 0.8 1.1 1.1 8.1 7.9 20.2 2.4 0.0 0.0 0.3 2.1 28.2 38.1 0.7 1.8 0.0 4.6 12.6 3.6 10.3 0.0 3.4 2.3 0.0 35.0 0.8 6.9 5.5 2.6 9.7 0.0 33.9 1.5 14.4 1.1 6.1 8.1 0.0 6.5 25.8 60.1 4.4 0.0 0.0 17.1 7.3 2.8 0.0 0.1 1.7 1.7 19.5 0.0 2.4 0.7 10.0 0.0 5.4 0.1 48.0 11.5 35.7 25.8 3.0 0.0 14.8 0.0 0.7 0.1 0.0 13.5 8.4 0.1 0.0 1.0 0.0 0.0 3.3 0.0 0.1 3.3 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.1 0.0 0.0 9.0 0.0 0.0 1.0 2.0 1.8 1.1 1.9 1.6 2.2 2.7 1.5 2.3 1.7 2.4 2.4 3.5 67.3 6.7 0.3 2.9 5.4 27.0 40.5 5.7 3.2 6.4 9.8 3.1 1.5 37.5 5.5 0.0 1.2 3.2 240.7 0.0 57.7 11.3 31.8 7.5 4.1 7.7 0.0 0.1 38.2 0.8 11.5 30.5 37.2 0.0 0.4 1.8 0.1 1.2 0.0 0.5 31.6 14.2 17.6 3.8 2.7 0.6 5.6 3.6 2.8 3.2 4.8 0.0 1.0 0.5 164.5 75.6 1.2 2.1 65.3 139.0 0.1 17.9 7.2 0.0 2.7 8.9 13.8 3.5 142.0 24.2 3.1 2.9 1.2 23.3 241.6 CDKN3 "CDI1, KAP" ENSG00000100526 "Cyclin dependent kinase inhibitor 3" Q16667 14 54396849-54420218 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 207.0" "Cell type enhanced" "Detected in many" "Early spermatids: 2630.9;Late spermatids: 659.4;Spermatocytes: 606.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.8" "Group enriched" "Detected in all" 6 "NK-cells: 6.4;T-cells: 18.8" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005285, HPA039311, HPA058874" Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB005285: AB_2078884, HPA039311: , HPA058874: AB_2683842" "unprognostic (3.46e-2)" "unprognostic (9.95e-2)" "unprognostic (5.79e-2)" "unprognostic (6.78e-3)" "unprognostic (2.73e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-3)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.50e-3)" "unprognostic (2.85e-3)" "prognostic unfavorable (7.46e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.71e-1)" "unprognostic (7.30e-2)" "unprognostic (7.92e-2)" "unprognostic (4.31e-2)" 3.4 1.6 2.8 12.2 2.7 43.4 3.4 5.0 4.2 2.2 3.4 13.9 12.4 2.8 0.4 10.2 1.3 2.9 5.3 2.9 3.1 2.0 2.4 2.1 28.4 2.5 2.7 1.3 1.1 0.5 1.6 6.7 3.3 1.6 16.9 2.6 3.3 0.7 3.0 5.9 12.6 7.4 2.1 4.9 5.0 207.0 3.5 30.9 1.7 4.1 30.0 5.8 4.1 2.6 276.7 102.5 74.0 78.2 12.5 15.3 46.5 63.1 97.0 135.8 146.9 81.8 136.5 139.9 44.4 96.7 135.9 195.9 114.6 78.3 245.6 169.5 59.3 65.8 69.0 126.8 10.1 86.2 47.6 5.4 4.9 84.3 138.3 44.4 88.4 129.8 36.1 162.2 159.8 186.9 118.1 67.9 27.9 254.7 216.4 72.7 66.6 29.7 70.5 56.9 30.6 42.0 118.7 67.4 52.5 54.6 142.9 69.4 33.0 59.2 195.8 91.7 155.0 38.6 47.4 91.4 98.6 120.4 110.9 0.0 1.3 1.3 1.6 1.7 0.7 2.1 5.5 4.8 1.8 0.9 2.9 2.3 1.0 6.4 1.2 1.5 18.8 3.1 2.8 2.7 5.0 4.2 2.9 3.1 2.5 2.7 3.3 2.1 3.5 2.6 1.4 0.0 0.0 0.7 10.5 9.3 4.3 9.7 4.6 3.2 6.4 11.6 9.7 0.0 2.4 1.8 2.1 42.6 2.7 7.3 0.0 3.5 2630.9 2.7 3.5 6.8 7.8 125.5 2.5 2.4 35.0 10.2 9.2 3.5 7.0 31.3 6.1 3.1 37.7 5.0 3.9 17.9 4.1 9.8 8.8 659.4 21.5 8.9 1.8 1.0 2.9 1.7 0.0 0.0 0.2 1.9 7.2 10.5 41.0 4.0 3.4 2.8 0.2 2.9 0.0 3.0 20.5 606.9 39.8 22.5 6.5 4.1 8.3 3.9 31.2 5.3 CDON "CDO, CDON1, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 58.3;Fibroblasts: 23.5;Inhibitory neurons: 49.5;Muller glia cells: 39.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 23.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;ASC diff: 32.7;RH-30: 48.9;SuSa: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB012422, HPA017377" Uncertain NA NA 15000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB012422: AB_2260246, HPA017377: AB_1846453" "prognostic favorable (1.35e-4)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-4)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (5.83e-3)" "unprognostic (1.86e-4)" 12.6 0.7 1.9 1.6 2.0 0.0 5.1 23.0 4.0 7.9 1.2 12.4 1.0 14.0 2.1 1.7 14.2 4.8 4.0 1.6 1.8 0.8 1.2 2.7 1.1 2.2 1.9 20.6 1.2 2.5 3.0 2.7 2.7 1.3 1.6 10.1 1.7 2.8 1.2 9.9 2.9 17.0 0.5 0.7 4.6 3.6 2.3 2.8 18.5 1.6 1.5 2.5 3.0 2.1 1.6 3.2 28.4 2.8 32.7 14.5 0.4 0.5 2.9 0.9 0.3 1.1 9.4 1.4 6.8 0.6 3.3 0.4 7.1 1.0 0.8 5.5 6.3 0.5 6.5 2.9 6.4 0.4 1.8 4.5 1.2 0.6 0.0 12.2 0.3 4.8 0.1 1.9 2.7 0.4 3.6 1.0 2.6 0.8 3.7 1.1 48.9 0.9 1.7 0.5 2.4 9.6 3.7 0.3 4.7 23.8 2.4 1.0 0.5 3.2 2.2 6.3 3.3 2.5 5.5 0.2 2.0 1.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 23.0 4.0 1.6 1.8 2.2 1.9 2.7 0.5 2.3 2.1 3.0 6.4 9.9 11.1 0.1 15.2 1.4 0.8 2.2 5.1 5.4 1.9 5.2 2.8 5.6 0.0 16.7 0.6 0.1 0.2 0.0 1.3 3.1 1.7 0.5 3.0 7.7 0.4 58.3 0.6 0.4 23.5 1.5 1.1 0.0 1.8 1.1 2.1 0.3 0.0 49.5 0.3 0.0 0.0 7.6 2.7 14.9 0.2 3.6 2.8 0.1 39.3 0.0 14.1 5.8 2.4 0.4 11.3 0.8 1.1 0.6 0.5 4.2 4.6 0.0 2.9 2.7 1.8 3.8 0.5 10.7 0.7 0.6 13.2 0.4 1.6 CDSN D6S586E ENSG00000204539 Corneodesmosin 6 31115087-31120446 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "skin 1: 696.5" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 2.6;Gastric mucus-secreting cells: 2.0;Glandular and luminal cells: 7.1;granulocytes: 4.5;Suprabasal keratinocytes: 5.3" "Group enriched" "Detected in some" 8 "head and neck cancer: 2.4;melanoma: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "A-431: 1.6" "Region enhanced" "Detected in some" "cerebral cortex: 1.5" "Not detected" "Not detected" "HPA044730, HPA054184" Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA044730: AB_10964923, HPA054184: AB_2682409" "unprognostic (1.46e-1)" "unprognostic (6.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (8.80e-2)" "unprognostic (8.13e-2)" "unprognostic (3.92e-4)" "unprognostic (3.92e-3)" "unprognostic (1.74e-4)" "unprognostic (6.34e-2)" "unprognostic (2.75e-1)" "unprognostic (2.22e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.1 0.0 0.1 3.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 696.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.6 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.9 0.4 2.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 7.1 4.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 1.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.2 CDT1 "DUP, RIS2" ENSG00000167513 "Chromatin licensing and DNA replication factor 1" Q9H211 16 88803789-88809258 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 38.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.4;Erythroid cells: 71.3;Extravillous trophoblasts: 92.0;Spermatogonia: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 149.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017224 Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA017224: AB_1846468" "unprognostic (1.33e-1)" "unprognostic (2.04e-2)" "unprognostic (7.32e-2)" "unprognostic (2.67e-1)" "unprognostic (4.34e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (3.44e-3)" "unprognostic (2.81e-2)" "unprognostic (4.59e-2)" "unprognostic (1.21e-1)" "unprognostic (9.34e-2)" "prognostic unfavorable (2.69e-6)" "unprognostic (7.72e-3)" "unprognostic (5.79e-2)" "unprognostic (2.80e-2)" "unprognostic (8.54e-2)" 0.7 0.8 0.8 3.8 1.2 38.5 0.7 2.5 1.3 1.7 0.0 3.3 4.1 0.5 0.2 6.7 0.5 0.2 0.5 0.8 2.3 0.7 1.0 1.3 4.8 2.2 1.1 0.4 0.6 1.3 2.1 2.8 1.9 0.7 1.6 0.4 1.1 0.2 0.1 3.6 3.9 0.6 0.7 3.1 2.4 3.5 1.1 8.7 0.6 0.0 3.3 0.5 2.3 1.0 33.6 34.5 16.5 25.3 0.7 3.4 64.2 24.1 6.6 19.4 12.0 79.3 33.8 51.4 24.2 5.5 12.7 46.0 21.6 17.7 6.2 18.2 92.1 51.8 28.8 59.9 0.3 28.8 21.5 1.8 1.4 19.8 4.4 1.6 5.9 60.9 80.8 18.4 7.6 90.6 109.3 149.4 41.8 12.2 31.6 120.3 22.9 42.4 4.3 23.8 36.6 26.2 44.4 13.1 16.9 7.4 39.0 55.9 5.9 24.6 42.6 37.2 35.4 61.4 55.7 73.6 19.3 71.9 31.6 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.7 0.4 0.1 0.1 0.7 0.2 0.8 1.2 2.5 1.3 0.8 2.3 2.2 1.1 1.9 0.7 1.1 1.0 0.4 0.0 1.1 0.7 4.9 11.2 4.3 1.4 7.4 0.7 5.4 7.5 2.2 1.5 1.7 1.8 0.0 51.4 2.2 12.7 1.9 1.1 0.4 1.4 1.4 2.2 2.4 71.3 0.2 0.0 92.0 5.2 9.2 2.2 0.0 29.0 0.4 1.0 19.5 0.0 0.8 16.1 4.1 5.6 5.5 1.2 0.3 2.8 1.8 0.0 1.9 1.5 4.1 0.0 0.6 0.6 2.3 0.4 23.1 2.2 2.0 1.6 2.1 1.9 0.0 2.1 3.4 6.6 37.1 10.8 7.1 24.8 5.4 5.7 30.1 4.4 CDYL "CDYL1, DKFZP586C1622" ENSG00000153046 "Chromodomain Y like" Q9Y232 6 4706159-4955551 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Lyase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035578 Enhanced Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 52: Non-specific - Ribosome" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "HPA035578: AB_2674685" "unprognostic (1.25e-1)" "unprognostic (8.99e-2)" "unprognostic (6.03e-2)" "unprognostic (2.38e-3)" "prognostic favorable (1.53e-4)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.62e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.09e-1)" "unprognostic (5.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (2.60e-2)" "unprognostic (3.94e-1)" 14.0 6.0 6.9 10.2 6.8 20.0 11.5 5.0 6.7 15.0 4.9 13.0 7.0 15.2 10.5 16.8 10.6 8.4 10.4 6.0 6.4 7.2 5.6 8.9 12.1 6.6 6.2 9.9 7.5 12.4 5.1 18.2 6.0 7.6 13.2 6.7 9.0 11.9 19.5 17.8 9.0 14.5 5.6 9.6 9.2 9.0 6.7 9.3 9.7 12.7 12.9 15.6 13.0 6.9 23.7 22.1 30.1 25.5 23.3 15.9 34.4 23.1 17.9 21.3 22.9 18.0 17.2 5.3 22.1 17.6 33.3 19.8 24.2 28.2 24.9 16.4 20.2 20.9 21.0 16.4 28.5 27.9 21.7 12.5 49.8 25.0 37.5 12.9 20.6 19.2 37.9 16.2 10.8 22.9 14.8 25.9 32.6 17.9 21.3 19.0 26.2 43.7 14.7 20.5 25.5 15.4 28.5 24.9 36.9 86.5 15.0 26.3 28.1 25.2 21.6 18.5 26.8 33.7 57.8 18.4 8.3 17.7 28.1 5.3 1.3 0.6 1.5 0.6 1.1 1.0 1.1 1.2 1.6 1.1 0.7 1.1 0.4 1.6 0.8 6.8 0.1 1.3 6.9 6.8 5.0 6.7 6.0 6.4 6.6 6.2 6.0 5.6 6.7 6.9 32.7 19.2 9.4 28.7 18.4 37.3 23.9 11.9 10.8 16.7 31.2 35.8 18.8 14.3 12.0 14.7 22.9 12.9 64.5 44.7 15.6 10.8 62.8 26.9 43.2 22.9 32.3 41.5 52.3 10.4 22.0 18.7 6.1 60.3 5.7 24.3 18.9 11.7 10.5 45.4 41.5 26.6 6.1 17.3 57.9 74.9 5.9 28.1 8.8 101.2 22.7 25.4 19.6 54.3 64.1 16.8 41.8 8.2 22.3 30.1 4.6 10.7 12.1 25.7 6.6 29.7 20.9 10.4 25.3 9.8 41.9 63.8 17.5 10.9 22.6 56.9 CEACAM1 "BGP, BGP1, CD66a" ENSG00000079385 "CEA cell adhesion molecule 1" P13688 19 42507304-42561234 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 246.3" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 335.2;Distal enterocytes: 731.7;Paneth cells: 585.4;Prostatic glandular cells: 244.9;Urothelial cells: 618.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 43.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "eosinophil: 43.6;neutrophil: 26.3" "Lineage enriched" "Detected in many" 13 "granulocytes: 43.6" "Group enriched" "Detected in many" 5 "CAPAN-2: 30.6;Hep G2: 101.0;OE19: 80.9;RT4: 59.2;SK-MEL-30: 67.4" "CAB002146, HPA011041" Enhanced "Intracellular and membrane" NA NA 130000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB002146: AB_563614, HPA011041: AB_1078481" "unprognostic (7.13e-3)" "unprognostic (2.15e-1)" "unprognostic (2.67e-2)" "prognostic favorable (6.32e-7)" "unprognostic (3.04e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-1)" "unprognostic (4.45e-2)" "unprognostic (4.43e-1)" "unprognostic (5.46e-3)" "unprognostic (4.87e-2)" "unprognostic (4.03e-1)" "unprognostic (1.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (7.55e-2)" "unprognostic (5.52e-3)" 11.9 10.6 1.3 31.1 0.8 74.5 13.3 3.2 1.8 16.4 0.0 246.3 53.3 11.1 3.9 64.9 6.0 7.4 4.0 1.9 0.0 31.9 60.5 6.8 4.3 0.4 0.1 1.1 2.4 1.7 3.8 33.1 0.5 20.2 141.2 0.6 58.9 10.3 2.7 3.3 51.0 13.1 0.0 7.9 19.9 3.7 0.2 2.3 3.1 3.1 21.5 37.0 29.2 0.0 0.6 5.6 0.3 0.3 0.0 0.0 14.4 0.0 0.2 1.0 0.5 2.3 30.6 1.7 12.2 0.0 3.2 0.8 0.0 7.9 0.4 0.1 0.5 0.3 0.2 101.0 1.7 0.2 13.3 0.0 0.1 0.1 0.1 0.0 0.7 1.4 0.0 5.0 0.0 3.2 0.3 0.2 0.9 80.9 1.7 2.6 0.0 1.3 0.6 59.2 0.5 0.2 0.0 0.2 67.4 7.3 0.3 0.0 2.1 0.3 1.2 1.4 0.5 1.8 0.0 3.7 0.2 0.4 1.0 0.8 0.0 43.6 0.1 1.7 0.3 3.3 0.9 0.4 0.2 0.8 0.6 0.2 26.3 0.1 3.3 0.1 2.7 0.6 1.3 0.8 3.2 1.8 1.9 0.0 0.4 0.1 0.5 0.0 0.2 0.0 16.7 6.4 8.2 1.0 6.0 1.3 335.2 10.4 2.8 6.0 16.3 12.7 1.8 7.2 14.7 0.0 4.2 2.0 0.7 731.7 0.0 21.3 3.5 5.0 5.2 22.3 17.3 0.4 1.7 16.1 9.4 2.9 12.8 28.7 8.9 4.6 41.4 37.7 1.4 5.0 1.4 46.1 4.1 5.9 3.1 0.2 0.0 2.6 7.2 0.0 0.9 1.3 2.1 0.5 0.6 58.7 585.4 0.7 0.2 244.9 97.5 11.1 3.9 6.4 0.0 2.7 3.1 4.3 3.9 9.2 1.0 0.7 5.5 2.2 33.2 618.9 CEACAM19 CEAL1 ENSG00000186567 "CEA cell adhesion molecule 19" Q7Z692 19 44662278-44684359 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.9;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.2;RPTEC TERT1: 15.8;TIME: 20.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "HPA014462, HPA052865" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Nucleoli, Mitochondria" Nucleoplasm "HPA014462: AB_2669006, HPA052865: AB_2681976" "unprognostic (2.91e-1)" "unprognostic (5.29e-3)" "unprognostic (6.96e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-2)" "unprognostic (8.43e-2)" "unprognostic (5.22e-2)" "unprognostic (1.15e-2)" "unprognostic (9.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.77e-1)" "unprognostic (3.26e-9)" "unprognostic (8.01e-3)" "unprognostic (9.62e-2)" "unprognostic (1.31e-1)" "unprognostic (2.70e-1)" 3.9 5.6 3.7 1.3 3.7 1.5 3.8 4.9 5.1 7.0 3.5 4.7 3.0 5.2 1.7 5.1 6.8 2.4 11.7 4.0 3.8 9.4 8.2 8.2 1.1 2.8 3.0 6.6 8.9 1.5 7.0 2.2 2.7 7.8 3.4 2.4 5.7 3.1 13.8 12.4 3.8 3.1 1.9 3.5 4.6 5.7 3.7 0.9 6.5 3.4 2.2 4.2 8.7 4.7 5.1 10.3 1.5 1.0 3.5 4.0 3.8 2.8 4.2 0.9 1.8 0.4 1.1 0.1 1.0 3.8 1.0 6.2 2.6 1.1 0.8 1.5 5.8 0.1 6.7 1.7 3.6 0.2 1.0 1.3 10.0 2.6 6.1 12.2 2.4 0.7 0.3 0.3 1.4 1.2 0.0 0.6 0.9 1.4 1.1 0.0 1.8 0.2 15.8 1.2 1.9 0.5 1.1 1.1 0.9 1.4 1.4 0.3 20.9 0.4 6.8 1.5 0.9 0.1 0.3 0.0 0.5 2.0 1.7 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.7 3.7 4.9 5.1 4.0 3.8 2.8 3.0 2.7 1.9 3.7 4.7 3.6 3.2 2.2 2.0 0.0 2.0 0.9 2.1 1.2 2.9 1.9 1.5 4.5 1.5 2.4 0.0 0.0 0.2 0.1 2.1 0.0 1.6 3.8 0.9 0.9 4.1 1.8 0.0 7.9 3.3 0.2 1.0 3.6 2.4 0.0 0.8 4.6 2.6 0.3 0.0 6.1 2.3 4.1 0.6 0.8 1.9 3.1 0.5 0.0 1.9 0.4 0.3 1.0 2.0 2.4 4.5 2.6 2.6 0.0 1.8 1.2 0.4 1.8 0.6 0.0 8.8 1.7 3.1 0.9 1.2 6.0 0.0 0.2 1.6 2.5 0.9 CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Cell type enhanced" "Detected in some" "Kupffer cells: 41.1;Macrophages: 20.9;monocytes: 9.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cell line enriched" "Detected in single" 6 "U-937: 4.1" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" 2.1 0.5 0.1 4.8 0.1 21.3 0.5 0.1 0.2 0.4 0.2 0.7 0.3 0.3 0.8 1.0 1.0 1.0 0.8 0.1 0.1 0.8 1.0 5.7 0.9 0.2 0.2 0.2 1.2 0.0 0.3 0.3 0.2 1.1 0.2 0.0 0.8 0.0 0.2 0.3 1.8 1.0 0.1 32.6 0.8 0.1 0.2 0.3 0.4 0.6 0.6 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 30.1 5.6 0.0 23.1 0.1 0.7 1.2 0.0 23.3 0.0 0.7 0.0 122.7 0.0 9.9 0.2 11.3 12.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.0 3.9 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.1 0.0 0.0 0.0 0.0 41.1 1.6 0.2 0.0 20.9 1.8 1.9 9.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 981.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 1389.2;Intestinal goblet cells: 395.0;Paneth cells: 777.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 56.9" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 23000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" 3.2 0.1 0.0 185.6 0.0 0.2 4.0 0.3 0.1 38.5 0.2 981.2 22.7 1.3 0.2 232.0 0.8 0.8 0.1 0.1 0.0 0.9 0.2 30.2 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.5 942.7 0.0 29.2 3.3 0.1 3.5 61.4 28.7 0.0 0.1 163.2 0.3 0.1 0.2 1.0 0.0 36.9 10.4 71.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.3 56.9 1.1 0.2 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 32.1 4.1 0.0 2.7 0.0 1.0 12.3 0.0 0.0 0.1 0.0 0.4 0.0 34.8 0.0 0.0 0.0 0.0 1389.2 0.0 3.4 0.4 0.0 0.0 0.2 65.7 0.0 0.1 0.9 0.0 0.4 22.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 395.0 4.1 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 21.3 777.3 0.0 0.1 16.5 10.2 0.0 4.5 0.0 0.0 0.1 0.4 0.8 0.5 1.9 0.0 0.0 1.2 0.0 192.3 124.4 CEACAM6 "CD66c, NCA" ENSG00000086548 "CEA cell adhesion molecule 6" P40199 19 41750977-41772211 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 181.5;esophagus: 195.2;intestine: 220.3;lung: 286.7;salivary gland: 177.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 942.3;Club cells: 322.1;Distal enterocytes: 640.1;Paneth cells: 391.1;Urothelial cells: 182.3" "Group enriched" "Detected in many" 4 "cervical cancer: 139.4;colorectal cancer: 500.8;lung cancer: 344.1;pancreatic cancer: 437.5;stomach cancer: 231.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 11 "OE19: 1799.0" "CAB008370, HPA011041" Enhanced NA NA 86000000 "Cluster 24: B-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB008370: AB_592067, HPA011041: AB_1078481" "unprognostic (1.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.62e-2)" "unprognostic (8.22e-2)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (2.32e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "unprognostic (5.22e-2)" "unprognostic (3.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.42e-4)" "unprognostic (4.08e-1)" "unprognostic (8.71e-3)" "unprognostic (2.85e-1)" "unprognostic (7.68e-2)" 2.0 0.4 0.3 29.7 1.2 181.5 2.7 0.6 0.6 39.2 0.0 195.0 33.0 0.6 1.8 195.2 8.2 130.1 0.2 0.2 0.0 0.3 0.7 286.7 0.3 0.3 0.1 0.4 5.2 0.1 0.3 0.5 0.2 2.4 220.3 0.0 177.6 1.4 0.1 6.8 24.4 6.6 0.0 2.4 15.5 0.4 0.3 2.1 0.3 0.0 32.5 9.6 79.1 0.4 0.1 162.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 5.5 4.6 0.0 0.2 0.0 0.5 19.4 0.0 0.0 0.1 0.3 0.2 0.0 0.5 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.1 11.2 0.1 0.2 0.2 1799.0 4.5 0.1 0.0 0.1 1.0 0.7 1.8 0.1 0.0 4.2 0.0 0.2 0.6 1.9 0.4 0.2 0.3 0.5 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.5 0.1 0.0 3.1 0.3 1.2 0.6 0.6 0.2 0.0 0.3 0.1 0.2 0.0 0.3 0.4 0.0 942.3 84.5 0.0 2.3 0.0 4.9 17.9 0.0 0.0 3.5 2.0 0.2 75.8 322.1 0.0 0.0 0.0 0.0 640.1 0.0 77.0 0.2 0.4 0.1 1.3 5.4 0.0 0.1 16.3 0.0 1.3 1.5 0.8 7.0 0.0 0.4 0.3 0.0 0.0 0.1 102.3 14.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 156.7 391.1 0.0 0.0 24.2 5.7 0.0 71.8 0.0 0.0 0.0 9.9 0.0 0.1 15.6 0.0 0.0 1.2 0.0 31.7 182.3 CECR2 KIAA1740 ENSG00000099954 "CECR2 histone acetyl-lysine reader" Q9BXF3 22 17359949-17558149 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;retina: 15.6;skeletal muscle: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 109.4;Cone photoreceptor cells: 168.9;Oligodendrocyte precursor cells: 120.1;Oligodendrocytes: 137.7;Rod photoreceptor cells: 94.1" "Cancer enriched" "Detected in many" 6 "testis cancer: 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 15.5;HAP1: 14.4;K-562: 8.3;NTERA-2: 22.8;SCLC-21H: 10.1;SuSa: 9.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002943 Approved Approved Nucleoplasm,Vesicles No No "Cluster 54: Non-specific - Microtubule organization" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA002943: AB_1078496" "unprognostic (2.46e-2)" "unprognostic (4.10e-2)" "unprognostic (7.99e-2)" "unprognostic (1.92e-3)" "unprognostic (7.48e-3)" "unprognostic (2.46e-3)" "unprognostic (2.49e-1)" "unprognostic (6.67e-2)" "unprognostic (8.18e-2)" "unprognostic (3.94e-1)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (8.13e-6)" "unprognostic (1.13e-1)" "unprognostic (1.59e-1)" "unprognostic (6.56e-2)" "unprognostic (1.94e-2)" 0.7 0.4 5.2 0.2 12.8 0.5 1.0 22.5 8.3 1.4 1.2 1.2 0.2 2.3 0.6 0.4 1.7 0.2 3.4 5.3 8.0 1.3 7.6 2.6 0.1 9.8 9.0 2.9 2.6 0.0 6.4 1.0 8.7 1.0 0.3 15.6 0.9 0.2 21.8 0.9 0.5 0.9 5.4 0.4 0.5 3.5 9.8 0.2 2.2 10.6 0.2 1.3 1.0 12.7 0.2 0.1 15.5 5.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 0.7 0.1 14.4 0.0 0.0 0.0 7.2 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.5 8.3 0.0 0.0 0.1 0.0 0.5 22.8 0.0 0.0 1.8 1.0 0.1 0.0 5.1 10.1 0.0 0.0 0.2 0.9 9.0 1.6 2.5 0.1 0.1 3.4 0.0 0.0 5.8 1.4 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 12.8 22.5 8.3 5.3 8.0 9.8 9.0 8.7 5.4 9.8 12.7 1.9 6.4 10.6 109.4 0.3 0.0 1.1 0.2 0.0 22.1 0.7 0.6 11.8 0.0 0.8 1.8 168.9 10.1 0.0 0.0 0.0 0.1 6.3 6.3 6.2 2.0 0.0 0.0 2.3 0.2 2.5 3.1 0.0 17.2 0.0 3.5 4.2 10.7 0.7 5.0 4.3 0.0 0.0 0.3 0.3 4.0 1.2 1.4 0.0 34.7 0.2 18.3 0.0 120.1 137.7 0.1 0.0 1.2 0.8 1.8 0.0 1.4 0.9 94.1 6.6 33.9 3.2 1.9 15.9 0.1 0.1 33.0 0.2 0.4 0.0 3.6 CELF5 BRUNOL5 ENSG00000161082 "CUGBP Elav-like family member 5" Q8N6W0 19 3224661-3297076 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 21.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 93.1;Excitatory neurons: 88.7;Inhibitory neurons: 72.8;Oligodendrocyte precursor cells: 22.1" "Cancer enhanced" "Detected in some" "glioma: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.4;REH: 4.3;SCLC-21H: 4.3;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042012, HPA060336" Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "HPA042012: AB_10796896, HPA060336: AB_2684256" "unprognostic (1.09e-1)" "unprognostic (9.24e-2)" "unprognostic (9.25e-3)" "unprognostic (3.48e-2)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.17e-1)" "unprognostic (1.22e-3)" "unprognostic (1.35e-1)" "unprognostic (4.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.74e-3)" "unprognostic (1.23e-2)" "unprognostic (2.63e-2)" "unprognostic (1.25e-1)" "unprognostic (8.07e-2)" 0.0 0.2 13.5 0.0 15.1 0.0 0.5 0.0 21.9 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.5 0.0 0.0 15.7 14.4 0.1 0.2 0.0 0.0 0.0 0.0 4.1 0.5 1.3 0.9 0.0 0.0 0.2 0.1 4.4 0.8 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.3 2.1 6.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.6 0.0 0.0 3.4 1.4 0.0 4.3 0.0 0.0 0.0 0.0 4.3 2.6 0.2 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 15.1 0.0 21.9 15.7 14.4 0.0 0.0 0.0 0.0 6.4 0.0 0.1 0.0 0.0 3.3 0.2 0.4 2.1 0.0 0.0 93.1 3.9 6.6 2.2 2.8 0.0 0.0 0.0 0.4 0.2 1.6 0.0 0.6 19.3 0.2 0.2 0.4 1.2 0.0 88.7 0.2 0.1 0.4 0.0 0.6 0.0 12.1 0.0 0.8 0.1 8.4 72.8 1.4 0.0 0.3 0.3 15.5 0.3 0.3 0.0 8.4 0.0 3.4 0.0 22.1 3.2 0.4 0.1 2.2 0.0 2.3 0.1 0.4 0.0 3.7 0.0 1.1 0.8 2.5 7.7 0.0 0.3 0.0 0.3 1.4 1.6 0.9 CENPA "CenH3, CENP-A" ENSG00000115163 "Centromere protein A" P49450 2 26764289-26801067 "Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.0;Extravillous trophoblasts: 33.2;Granulosa cells: 24.2;Plasma cells: 17.8;Spermatogonia: 28.6" "Cancer enhanced" "Detected in many" "testis cancer: 24.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB008371, HPA073086" Enhanced Supported Nucleoplasm NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB008371: AB_591074, HPA073086: AB_2686569" "unprognostic (3.94e-2)" "unprognostic (1.38e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (1.13e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (2.88e-8)" "prognostic unfavorable (3.70e-4)" "unprognostic (1.69e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.21e-3)" "unprognostic (0.00e+0)" "unprognostic (5.74e-2)" "unprognostic (1.33e-1)" "unprognostic (7.68e-2)" "unprognostic (2.07e-1)" 0.2 0.3 0.0 4.0 0.0 3.7 0.4 0.1 0.1 0.5 0.0 2.9 4.1 0.7 0.0 3.7 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.4 7.3 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.1 2.6 0.0 0.6 0.0 0.0 3.6 2.9 0.9 0.0 2.0 1.6 2.2 0.1 13.3 0.1 0.0 8.4 0.7 1.1 0.0 86.4 21.0 34.9 19.3 2.4 4.5 24.3 26.2 22.2 37.3 31.5 15.4 30.0 25.7 16.2 10.4 45.7 25.6 28.9 15.3 37.7 77.3 25.6 44.0 11.0 28.6 0.8 26.7 49.0 0.4 1.6 16.1 24.4 6.7 22.1 33.7 36.7 58.5 32.5 30.1 39.0 42.2 26.6 35.3 34.3 45.4 53.6 30.8 17.5 5.5 27.5 26.7 25.7 32.7 23.6 12.9 18.2 27.2 12.6 23.9 54.2 27.9 46.4 51.5 53.5 107.3 11.1 54.7 46.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 5.2 6.2 0.7 1.9 1.8 0.0 2.0 2.5 2.7 0.0 0.5 0.0 0.0 15.3 1.0 2.3 0.0 0.5 0.6 1.6 1.6 1.5 4.2 45.0 0.1 0.2 33.2 4.9 2.6 3.0 0.0 24.2 3.9 0.6 15.7 0.0 0.1 6.6 0.0 2.9 2.8 0.1 0.9 4.4 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 1.4 0.0 17.8 2.1 0.8 0.2 0.1 0.0 0.0 0.6 3.9 16.1 28.6 12.5 5.3 3.4 3.4 1.5 11.1 2.0 CENPE "KIF10, PPP1R61" ENSG00000138778 "Centromere protein E" Q02224 4 103105349-103198445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein, Motor protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.0;lymphoid tissue: 9.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 75.1;Extravillous trophoblasts: 28.4;Granulosa cells: 32.0;Spermatocytes: 75.3;Spermatogonia: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011110, HPA042294" Enhanced Enhanced "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA011110: , HPA042294: AB_10797386" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (5.64e-3)" "unprognostic (2.55e-2)" "unprognostic (1.65e-1)" "unprognostic (3.44e-2)" "unprognostic (2.40e-8)" "unprognostic (2.49e-3)" "unprognostic (1.59e-2)" "unprognostic (3.38e-1)" "unprognostic (4.88e-5)" "unprognostic (1.15e-2)" "unprognostic (0.00e+0)" "unprognostic (9.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (2.37e-1)" 0.4 0.2 0.4 2.7 0.4 10.0 0.6 0.3 0.5 0.4 0.4 1.8 1.5 0.6 0.0 2.0 0.2 0.8 0.2 0.3 0.6 0.2 0.5 0.8 5.6 0.5 0.5 0.1 0.1 0.3 0.0 1.4 0.9 0.3 2.0 0.4 0.3 0.2 0.0 2.0 1.7 1.1 0.3 1.2 1.1 4.1 0.5 9.2 0.2 0.6 4.9 0.8 0.6 0.5 42.6 11.8 42.2 20.5 2.7 6.2 8.4 36.7 18.2 26.9 17.9 19.6 22.2 28.6 9.2 13.7 19.2 18.2 30.3 15.1 42.2 35.9 11.3 33.5 26.8 13.6 0.4 39.9 18.6 1.8 1.1 21.7 18.0 6.0 22.9 25.2 34.4 32.5 34.8 15.6 31.5 18.9 13.8 17.0 17.9 20.9 38.5 9.3 8.0 8.4 19.3 11.5 32.9 22.9 9.0 16.0 12.9 13.9 26.1 25.8 27.2 27.2 38.6 15.9 28.6 28.8 14.2 21.7 27.8 2.9 0.0 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.5 0.2 0.6 0.0 0.4 0.4 0.3 0.5 0.3 0.6 0.5 0.5 0.9 0.3 0.5 0.5 1.4 3.2 2.2 1.0 6.6 3.6 1.5 2.9 0.0 7.6 1.8 2.7 1.9 0.0 1.3 0.0 8.4 12.7 3.9 4.7 0.0 0.5 7.7 3.5 5.7 4.2 1.2 75.1 2.0 0.0 28.4 6.5 4.6 6.9 7.0 32.0 4.2 0.9 14.1 0.0 1.9 4.3 4.1 10.4 5.7 3.5 0.9 9.6 0.0 0.0 6.0 1.3 2.1 0.5 3.1 1.8 1.4 2.6 16.0 1.4 0.8 0.3 0.3 2.6 0.0 5.7 7.4 75.3 51.0 8.3 2.8 3.6 6.6 7.0 11.6 1.9 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664571 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.8;lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Early spermatids: 84.4;Erythroid cells: 268.7;Extravillous trophoblasts: 78.8;Granulosa cells: 165.8;Spermatocytes: 107.5;Spermatogonia: 107.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 0.8 1.1 0.1 4.4 0.1 28.8 1.8 0.0 0.3 1.3 0.5 5.8 6.1 1.8 0.1 8.6 0.6 0.7 0.4 0.3 0.0 0.4 0.9 0.9 8.5 0.3 0.5 0.7 0.3 0.2 0.1 3.1 0.3 0.5 5.7 1.0 1.4 0.1 0.2 6.2 4.3 2.5 0.2 2.4 2.6 10.5 0.5 33.0 0.4 0.6 10.0 1.4 2.6 0.3 123.7 68.4 144.3 75.8 5.4 7.2 56.3 74.6 30.3 43.9 42.8 54.6 74.1 116.3 43.1 41.7 39.8 74.7 89.9 49.2 74.1 102.6 56.6 96.0 111.4 78.6 0.8 137.0 50.5 2.7 3.8 63.3 72.3 12.7 46.9 52.6 88.4 68.0 79.4 47.0 81.5 54.3 127.9 36.8 30.0 85.7 203.7 38.6 43.2 30.3 67.4 91.2 100.7 66.2 38.9 76.2 79.1 51.9 61.7 78.9 92.2 66.2 155.9 51.6 60.7 108.7 34.4 96.7 71.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.3 0.5 0.3 0.2 0.5 0.3 3.0 0.0 3.1 0.0 11.5 9.3 2.8 11.2 3.4 4.7 10.0 6.7 1.9 1.5 9.9 0.0 0.0 53.3 10.8 19.1 0.0 2.0 84.4 30.1 19.3 12.4 0.0 268.7 1.3 0.4 78.8 19.0 32.1 25.2 1.3 165.8 8.9 2.6 32.2 1.7 0.8 20.1 14.2 16.6 6.6 19.8 1.2 16.2 1.8 1.0 0.7 1.4 5.2 0.0 0.1 0.5 1.1 3.0 25.9 2.3 2.1 0.1 16.7 3.1 0.0 8.3 23.9 107.5 107.1 44.6 5.5 5.1 23.3 11.7 41.3 3.7 CENPH ENSG00000153044 "Centromere protein H" Q9H3R5 5 69189574-69210357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33.8;testis: 29.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 74.5;Spermatocytes: 222.7;Spermatogonia: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA036494 Approved Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "HPA036494: AB_10673354" "unprognostic (1.49e-1)" "prognostic favorable (6.86e-4)" "unprognostic (1.73e-2)" "unprognostic (3.16e-2)" "unprognostic (2.32e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.22e-5)" "unprognostic (6.14e-3)" "unprognostic (6.85e-2)" "prognostic favorable (2.50e-4)" "unprognostic (4.21e-2)" "unprognostic (8.80e-2)" "prognostic unfavorable (5.11e-15)" "unprognostic (1.17e-1)" "unprognostic (3.94e-1)" "unprognostic (2.58e-1)" "unprognostic (2.20e-1)" 4.2 2.0 1.4 7.5 1.7 33.8 7.7 1.7 2.0 3.9 1.0 7.4 6.5 4.5 2.1 7.5 4.0 1.8 4.0 1.5 1.6 1.6 3.6 2.8 17.7 1.6 1.5 3.9 1.5 2.0 1.4 5.2 1.6 3.3 8.1 2.5 2.9 2.3 4.0 9.2 5.9 3.7 1.4 5.2 3.7 29.7 1.6 18.5 2.5 4.0 18.8 3.8 4.4 2.2 64.6 19.4 88.6 70.2 5.8 18.3 48.0 31.2 32.6 66.9 71.8 26.5 79.6 138.9 36.6 18.1 39.1 47.0 59.0 70.4 85.1 42.7 41.4 32.7 32.5 26.4 2.0 47.1 32.1 7.1 14.6 43.6 47.7 18.9 23.2 73.7 58.7 53.3 52.2 35.6 152.4 67.3 78.1 20.7 17.0 93.2 118.2 108.2 21.1 22.9 61.6 81.9 34.6 22.8 27.5 47.7 31.9 31.4 11.4 33.4 56.1 44.5 78.7 65.5 106.3 111.8 51.1 94.2 64.7 1.0 2.0 3.0 4.7 3.5 7.7 13.3 7.9 6.0 3.1 14.1 9.9 8.6 0.4 8.6 4.2 6.7 9.7 4.8 1.4 1.7 1.7 2.0 1.5 1.6 1.6 1.5 1.6 1.4 1.6 2.2 4.8 0.0 2.6 1.0 18.3 36.7 17.7 17.4 9.6 3.4 10.8 11.7 3.3 4.3 7.1 0.0 0.0 37.4 9.2 5.1 0.0 12.3 26.5 5.5 5.1 6.9 1.2 74.5 1.3 9.1 49.0 7.4 2.6 4.8 5.1 22.4 4.6 1.1 17.0 0.0 1.1 9.5 12.2 7.5 18.2 22.5 3.7 6.3 8.8 1.0 4.3 7.3 6.2 1.0 0.9 7.0 2.5 4.9 14.4 6.9 1.4 3.4 10.8 3.5 19.7 6.4 9.3 222.7 222.8 12.1 19.2 10.0 12.0 6.9 15.9 15.2 CENPI "CENP-I, FSHPRH1, LRPR1, Mis6" ENSG00000102384 "Centromere protein I" Q92674 X 101098218-101163681 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 6.8;lymphoid tissue: 7.1" "Cell type enhanced" "Detected in some" "Erythroid cells: 4.8;Excitatory neurons: 2.9;Extravillous trophoblasts: 4.7;Granulosa cells: 3.2;Oligodendrocytes: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061297 Supported "Nuclear bodies,Cytosol" NA Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" Cytosol "HPA061297: AB_2684471" "unprognostic (3.10e-3)" "unprognostic (9.71e-2)" "unprognostic (1.86e-2)" "unprognostic (3.51e-3)" "unprognostic (1.24e-1)" "unprognostic (2.46e-2)" "unprognostic (5.78e-6)" "unprognostic (2.96e-2)" "unprognostic (7.71e-3)" "unprognostic (3.62e-3)" "unprognostic (1.20e-3)" "unprognostic (4.51e-2)" "unprognostic (2.50e-13)" "unprognostic (1.25e-2)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (1.42e-1)" 1.1 0.6 0.9 3.1 1.0 6.8 1.2 2.0 1.0 1.0 0.5 2.7 2.8 1.8 1.4 2.6 0.6 1.4 0.5 1.1 1.1 0.4 0.8 1.0 5.4 1.4 0.6 2.3 0.9 0.2 0.0 2.5 1.4 1.2 3.5 1.8 0.5 0.6 0.2 3.2 2.3 2.7 0.1 1.6 1.5 1.2 1.0 7.1 0.8 0.6 6.3 1.4 0.8 2.9 44.9 30.3 36.6 28.1 4.6 8.2 16.4 47.5 25.2 47.1 94.5 40.9 28.0 32.7 16.5 18.8 72.5 25.7 54.2 25.3 65.4 20.6 13.8 20.2 43.5 15.6 0.5 26.8 21.2 3.3 2.2 62.5 7.7 13.5 40.7 23.3 14.5 58.3 46.1 31.5 26.7 9.8 28.3 21.2 36.8 24.7 53.0 21.0 11.8 26.4 23.4 12.3 58.1 16.3 9.6 33.0 16.2 8.6 16.7 44.0 36.6 41.2 38.3 9.1 23.3 36.5 17.3 35.2 34.7 0.7 0.5 0.6 0.4 0.7 0.3 0.6 0.4 0.6 0.2 0.4 0.4 0.4 1.1 0.7 0.7 0.7 0.8 0.3 0.9 1.0 2.0 1.0 1.1 1.1 1.4 0.6 1.4 0.1 1.0 2.9 0.5 0.0 0.0 2.3 0.9 0.3 0.1 0.6 0.0 0.5 0.4 0.3 0.4 0.0 0.7 0.0 0.0 1.9 0.5 0.8 0.0 0.2 0.2 0.4 0.8 0.5 0.0 4.8 2.9 0.0 4.7 0.6 0.0 0.6 0.0 3.2 0.7 0.2 1.4 0.0 2.3 0.7 0.0 0.6 0.8 0.0 0.3 0.3 0.0 1.0 0.6 0.5 0.0 1.5 3.3 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.1 0.3 0.0 0.7 1.0 0.3 0.9 1.4 0.1 0.3 0.4 0.8 1.4 0.2 CENPK "CENP-K, FKSG14, SOLT" ENSG00000123219 "Centromere protein K" Q9BS16 5 65517766-65563168 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.6;lymphoid tissue: 22.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 50.9;Extravillous trophoblasts: 50.6;Spermatocytes: 101.3;Spermatogonia: 75.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (4.04e-2)" "unprognostic (1.77e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-2)" "unprognostic (1.85e-1)" "unprognostic (3.04e-3)" "unprognostic (3.69e-4)" "unprognostic (3.22e-3)" "unprognostic (9.59e-3)" "unprognostic (3.32e-2)" "unprognostic (3.16e-3)" "unprognostic (1.98e-2)" "unprognostic (6.33e-15)" "unprognostic (2.22e-1)" "unprognostic (2.97e-1)" "unprognostic (8.42e-2)" "unprognostic (3.11e-1)" 1.1 0.9 0.6 10.6 0.7 24.6 3.8 1.0 0.8 1.2 1.6 9.0 8.3 1.9 0.9 5.6 2.3 1.9 0.5 0.5 0.6 0.8 1.9 2.0 14.6 1.0 0.7 0.8 0.6 1.0 0.3 5.5 1.1 1.3 11.9 0.7 1.4 0.7 0.2 8.6 8.6 3.4 0.7 4.5 5.5 13.4 1.0 22.2 1.2 0.5 12.4 2.6 2.4 1.4 65.3 41.4 85.6 29.5 4.4 12.0 40.8 69.8 26.5 58.7 73.6 35.1 97.2 39.3 25.2 23.6 59.5 39.7 33.3 35.4 92.7 45.2 28.5 42.1 50.7 33.8 1.7 50.1 36.8 5.6 5.0 56.9 27.3 10.6 56.4 42.2 31.8 57.7 59.1 21.5 85.4 56.2 41.1 18.5 17.1 52.5 81.9 43.8 38.8 34.4 35.8 28.9 53.7 22.1 28.7 31.8 40.0 36.9 20.3 44.9 46.5 31.1 82.2 30.0 51.9 83.0 41.9 74.0 49.9 3.7 0.7 2.3 9.9 1.0 14.8 4.0 21.1 12.5 1.7 7.0 28.5 20.2 1.7 10.2 1.1 1.6 23.2 10.0 0.6 0.7 1.0 0.8 0.5 0.6 1.0 0.7 1.1 0.7 1.0 1.4 2.7 0.0 3.4 0.3 11.7 23.6 8.5 14.0 4.6 1.6 6.0 7.9 0.9 0.0 8.1 0.0 0.0 28.8 18.7 5.8 1.9 3.1 27.6 25.5 4.5 5.7 0.0 50.9 3.1 1.0 50.6 6.3 9.2 7.2 2.5 22.7 3.9 1.1 22.4 0.0 2.3 14.7 8.2 1.9 12.0 17.4 1.5 5.7 1.8 11.2 1.8 0.6 7.2 2.0 1.4 2.3 2.1 1.5 14.1 2.2 1.1 0.3 7.1 1.1 0.0 2.3 9.1 101.3 75.1 17.0 8.1 6.7 20.7 3.9 15.8 11.4 CENPN "BM039, C16orf60, FLJ13607, FLJ22660" ENSG00000166451 "Centromere protein N" Q96H22 16 81006552-81033114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 64.2;Extravillous trophoblasts: 91.1;Spermatocytes: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052870 Supported Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA052870: AB_2681978" "unprognostic (1.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.15e-1)" "unprognostic (1.76e-2)" "unprognostic (2.15e-1)" "unprognostic (1.76e-2)" "unprognostic (3.69e-3)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (2.36e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.02e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.34e-2)" "unprognostic (7.42e-2)" "unprognostic (1.41e-2)" "unprognostic (7.99e-2)" 5.1 5.0 3.2 7.9 4.0 37.4 3.6 3.1 4.9 2.8 2.1 8.0 7.8 2.3 3.1 7.5 1.6 3.1 5.7 3.3 3.1 5.4 9.0 3.3 11.0 3.8 4.0 1.5 5.2 8.6 1.6 8.9 3.4 18.7 7.6 1.4 2.5 2.7 4.5 3.8 6.4 6.4 2.7 4.3 5.2 11.2 3.9 18.1 2.8 2.6 12.0 6.0 2.8 5.8 86.2 81.0 64.9 58.4 16.9 15.1 82.6 97.5 59.3 137.0 59.6 150.8 64.6 48.1 52.4 48.9 62.7 69.9 53.1 61.5 172.9 29.3 47.9 43.0 63.3 100.9 9.6 64.6 80.4 14.0 6.6 123.3 40.8 18.0 62.6 59.1 83.6 65.9 66.9 160.1 78.0 79.6 69.7 37.2 45.4 90.9 64.5 51.3 22.5 58.6 43.2 38.9 140.3 31.8 40.1 38.9 76.2 34.0 38.5 97.7 101.1 66.8 96.8 46.4 112.1 186.8 45.8 43.7 85.8 0.9 1.4 2.4 2.1 2.8 2.0 1.6 2.7 1.5 6.6 5.9 1.3 1.5 1.7 3.6 3.1 2.2 7.9 2.0 3.2 4.0 3.1 4.9 3.3 3.1 3.8 4.0 3.4 2.7 3.9 5.8 2.8 0.0 4.8 1.0 10.2 24.0 15.7 9.6 14.8 1.0 6.0 7.0 4.8 5.7 5.8 3.7 0.0 47.1 10.0 7.4 0.0 5.7 41.8 4.5 3.8 5.8 1.2 64.2 1.9 6.5 91.1 9.7 11.7 6.4 6.3 13.2 6.8 6.3 27.2 0.0 1.1 12.8 12.2 9.7 20.2 40.9 2.8 10.4 7.2 1.0 4.4 0.8 0.0 0.5 6.1 5.1 4.0 3.4 34.7 13.6 5.1 8.8 1.8 0.4 0.0 7.1 10.0 52.3 39.1 32.7 16.3 27.2 10.9 6.3 22.0 16.6 CENPP "CENP-P, RP11-19J3.3" ENSG00000188312 "Centromere protein P" Q6IPU0 9 92325953-92620529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 21.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 63.3;Excitatory neurons: 73.4;Inhibitory neurons: 70.5;Microglial cells: 94.6;Oligodendrocytes: 74.5;Suprabasal keratinocytes: 100.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021787, HPA058945" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm Nucleoli "HPA021787: AB_1846524, HPA058945: AB_2683860" "unprognostic (5.48e-2)" "prognostic favorable (3.91e-4)" "unprognostic (1.20e-1)" "unprognostic (2.43e-3)" "unprognostic (2.64e-2)" "prognostic favorable (3.65e-4)" "unprognostic (4.88e-5)" "unprognostic (8.06e-2)" "unprognostic (3.51e-3)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (6.68e-3)" "unprognostic (9.20e-8)" "unprognostic (1.27e-2)" "unprognostic (5.12e-2)" "unprognostic (1.11e-1)" "unprognostic (2.04e-1)" 3.4 3.0 1.7 3.5 2.1 12.3 3.0 5.6 2.1 3.8 0.8 2.4 2.8 2.9 0.7 4.4 2.0 2.8 2.8 2.0 1.5 2.0 1.8 1.9 5.6 1.7 1.4 2.2 2.1 2.4 1.8 3.1 2.0 2.3 2.7 2.4 2.2 1.5 9.0 21.4 1.9 3.0 1.0 2.7 1.8 4.5 1.8 7.1 1.4 4.5 6.4 2.3 4.0 1.8 14.2 8.7 12.0 8.8 4.9 5.3 11.7 14.6 8.2 17.9 14.3 4.0 7.9 18.5 6.7 4.7 16.5 16.8 11.6 8.0 16.6 26.3 15.1 18.6 7.2 5.7 2.6 38.2 17.0 5.8 4.5 17.3 11.1 2.5 9.2 17.5 20.8 25.2 13.8 9.0 53.4 11.6 10.1 26.6 17.9 17.9 20.3 20.0 2.7 14.1 27.8 9.6 16.8 10.5 5.4 8.7 5.6 11.4 4.4 17.4 8.7 26.6 21.2 16.7 21.6 23.9 19.5 18.9 16.1 1.8 1.8 2.6 2.6 6.4 4.7 4.6 3.0 2.3 2.3 3.6 2.7 2.7 0.5 3.5 3.3 3.0 3.5 2.0 1.7 2.1 5.6 2.1 2.0 1.5 1.7 1.4 2.0 1.0 1.8 1.8 3.7 0.0 0.5 17.3 4.5 63.3 4.0 4.5 5.2 6.2 4.0 2.7 2.1 2.8 1.3 0.0 8.4 6.2 3.3 1.6 1.9 1.7 17.5 2.4 4.2 4.4 1.2 11.2 73.4 2.3 9.2 5.8 5.6 2.3 0.0 6.4 2.5 0.9 17.1 1.7 70.5 1.5 0.0 2.1 11.7 4.7 4.4 4.0 14.2 94.6 0.5 2.8 1.0 38.2 74.5 1.1 0.4 4.9 11.9 2.8 0.4 1.8 0.3 7.8 6.6 20.8 9.2 30.2 16.2 9.8 100.9 3.8 3.6 4.4 2.6 2.7 CENPW "C6orf173, CUG2" ENSG00000203760 "Centromere protein W" Q5EE01 6 126340115-126348875 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 50.6;testis: 39.5" "Cell type enhanced" "Detected in many" "Early spermatids: 329.7;Extravillous trophoblasts: 155.9;Spermatocytes: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA067285 Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA067285: AB_2685818" "unprognostic (3.51e-3)" "unprognostic (2.35e-1)" "unprognostic (3.26e-3)" "unprognostic (9.61e-3)" "unprognostic (3.78e-1)" "unprognostic (9.80e-3)" "prognostic unfavorable (1.21e-5)" "unprognostic (1.11e-2)" "unprognostic (2.82e-2)" "unprognostic (9.07e-2)" "unprognostic (5.86e-3)" "unprognostic (1.08e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.07e-1)" "unprognostic (1.85e-1)" "unprognostic (2.30e-1)" "unprognostic (1.22e-1)" 8.2 4.3 2.5 12.8 2.3 50.6 6.6 2.0 3.5 14.4 1.4 15.0 8.3 21.6 7.0 23.1 9.2 5.4 1.7 4.2 2.0 3.4 3.6 4.9 15.5 1.9 2.0 4.1 2.1 2.8 2.5 7.8 1.7 6.3 17.5 1.6 8.5 4.4 3.0 8.3 10.8 16.1 1.9 6.8 6.3 39.5 2.0 27.4 2.5 1.9 20.5 6.6 10.9 2.4 73.4 49.0 94.7 82.9 10.3 10.4 81.2 60.0 43.6 81.3 98.3 148.0 50.1 86.8 48.8 38.3 128.7 88.0 78.0 94.3 114.6 94.0 140.2 84.7 141.4 166.3 3.4 123.8 59.1 6.4 10.0 69.1 51.2 23.1 88.3 116.8 144.1 56.5 69.6 119.3 103.1 204.4 60.5 64.0 74.3 107.7 63.2 62.6 38.0 33.0 99.1 44.0 50.8 46.5 67.4 76.9 43.7 119.5 48.0 76.6 78.3 104.6 163.7 36.9 72.7 156.8 45.9 147.0 92.8 3.2 16.9 2.3 2.0 20.3 0.6 6.0 4.4 4.3 15.9 3.5 3.4 2.7 2.9 6.9 14.1 18.9 12.0 5.9 2.5 2.3 2.0 3.5 4.2 2.0 1.9 2.0 1.7 1.9 2.0 2.4 2.5 0.0 2.6 1.0 18.6 38.0 13.4 54.3 6.2 1.3 10.3 18.7 0.3 11.5 29.4 1.8 2.1 52.2 6.1 23.5 5.9 16.6 329.7 18.0 26.5 11.0 7.8 75.1 23.7 17.9 155.9 25.1 17.3 12.7 13.4 31.4 10.8 6.0 63.6 3.3 22.0 27.1 42.7 15.6 40.1 39.3 19.3 19.3 8.8 1.0 12.6 3.1 3.1 1.0 2.4 17.2 10.6 9.1 38.6 24.7 18.1 1.6 7.0 1.4 0.0 6.4 18.1 148.3 83.8 60.9 29.0 21.2 8.6 11.4 51.7 35.8 CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 49.0" "Group enriched" "Detected in many" 8 "Early spermatids: 1061.4;Late spermatids: 1606.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 32.0;RH-30: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (9.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.93e-1)" "unprognostic (6.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.11e-3)" "unprognostic (1.43e-2)" "unprognostic (7.99e-2)" "unprognostic (4.48e-3)" "unprognostic (3.37e-2)" "unprognostic (1.39e-3)" "unprognostic (3.50e-2)" "unprognostic (4.46e-3)" "unprognostic (1.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" 11.3 3.9 5.0 2.7 5.4 1.7 9.5 7.1 5.8 8.3 11.9 7.8 2.0 8.5 8.2 4.3 8.3 7.0 8.0 7.4 5.1 5.6 3.2 7.4 2.5 5.8 5.7 8.2 4.6 8.7 8.3 7.2 4.2 7.2 3.1 25.4 3.0 7.9 8.8 3.3 2.9 8.0 3.4 8.8 4.2 49.0 5.5 2.8 7.1 14.0 1.7 5.4 5.9 3.4 5.0 10.5 13.3 3.8 6.9 14.0 0.4 4.5 7.7 5.5 5.0 1.5 2.0 1.6 4.3 9.8 15.5 0.6 2.9 2.9 7.8 2.6 4.8 0.3 4.7 1.9 2.9 0.6 0.2 8.4 4.8 5.2 1.6 11.0 16.8 2.7 0.3 5.0 32.0 0.7 5.3 0.4 1.3 1.1 4.4 1.5 75.9 0.4 6.0 0.3 3.5 7.4 4.7 0.5 3.6 11.4 3.8 0.4 7.9 14.3 8.2 3.9 6.7 2.3 2.1 0.2 4.4 0.2 5.3 1.3 0.4 0.4 0.3 0.2 0.6 0.3 0.8 0.3 0.2 0.8 0.5 0.3 1.3 0.8 0.2 1.4 0.5 0.1 5.0 5.4 7.1 5.8 7.4 5.1 5.8 5.7 4.2 3.4 5.5 3.4 39.7 9.6 35.8 83.6 1.1 2.5 2.9 2.2 2.2 36.7 2.7 5.5 28.3 4.3 15.3 1.8 20.9 0.7 0.8 1.5 1.9 7.4 1061.4 15.3 15.8 25.4 1.8 0.4 117.4 4.7 1.5 12.4 1.5 3.3 2.5 11.2 19.2 0.2 1.8 1.7 103.8 0.3 0.0 0.8 11.3 1606.0 24.8 2.3 14.2 99.3 0.0 14.7 1.0 29.7 6.6 4.4 0.5 19.9 0.4 1.5 0.0 4.3 23.7 154.3 13.1 43.7 12.5 40.6 16.5 2.4 1.6 0.1 2.5 3.1 1.5 1.3 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4;testis: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Extravillous trophoblasts: 17.1;Granulosa cells: 19.8;Spermatocytes: 77.3;Spermatogonia: 17.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Approved "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 1.3 0.6 0.0 7.6 0.0 5.0 1.4 0.0 0.2 1.7 0.0 7.0 6.7 1.4 0.1 7.3 0.4 1.4 0.3 0.0 0.1 0.3 0.6 1.3 14.7 0.1 0.3 0.2 0.2 0.2 0.3 3.5 0.2 0.3 8.8 0.0 1.2 0.3 0.1 4.5 6.3 5.2 0.0 2.4 4.6 21.7 0.4 27.4 0.5 0.2 15.5 3.1 2.3 0.1 208.5 81.5 53.0 67.7 5.8 12.0 29.6 112.4 78.2 103.5 106.4 87.2 108.6 55.4 48.2 72.8 69.6 115.4 64.8 54.8 123.4 167.2 33.7 21.0 49.2 29.9 0.6 36.3 46.3 2.8 3.8 110.6 133.5 30.7 97.1 89.9 19.3 101.8 118.5 48.3 96.3 54.8 20.9 64.2 58.8 41.3 86.9 30.3 47.1 25.5 21.7 30.7 86.3 26.3 64.9 40.1 68.9 36.4 61.4 65.3 90.6 90.5 186.7 45.1 66.1 66.8 51.0 134.8 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.1 0.2 0.0 1.3 0.0 2.7 3.6 0.9 1.9 0.0 0.0 1.8 2.0 0.4 2.8 0.2 0.0 0.0 7.7 0.9 3.3 0.0 0.6 29.4 1.7 2.0 1.5 0.0 2.5 0.5 0.2 17.1 2.3 8.2 3.6 0.0 19.8 2.2 0.3 12.9 0.0 0.3 4.5 4.1 7.0 5.1 8.2 0.3 5.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.4 14.8 1.1 0.4 0.0 0.2 0.0 0.0 0.5 4.5 77.3 17.3 16.1 1.3 1.5 4.3 1.6 7.9 1.7 CEP85L "bA57K17.2, C6orf204, NY-BR-15" ENSG00000111860 "Centrosomal protein 85 like" Q5SZL2 6 118460772-118710075 "Disease related genes, Predicted intracellular proteins" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 29.9" "Cell type enhanced" "Detected in many" "Astrocytes: 266.1;Early spermatids: 445.2;Late spermatids: 742.5;Oligodendrocyte precursor cells: 251.9;Oligodendrocytes: 189.4" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029137, HPA029138, HPA029139" Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "HPA029137: AB_10600657, HPA029138: AB_10600874, HPA029139: AB_10601220" "unprognostic (3.25e-2)" "unprognostic (1.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.82e-1)" "unprognostic (2.19e-2)" "unprognostic (2.34e-1)" "unprognostic (7.24e-2)" "unprognostic (1.01e-2)" "unprognostic (8.37e-2)" "unprognostic (2.03e-1)" "unprognostic (1.39e-3)" "unprognostic (8.45e-2)" "unprognostic (2.87e-5)" "unprognostic (2.72e-3)" "unprognostic (2.44e-1)" "unprognostic (1.64e-1)" "unprognostic (1.85e-2)" 3.3 5.2 4.0 7.1 5.5 11.5 2.5 11.7 5.2 3.9 0.0 2.6 1.8 4.1 2.1 3.0 3.8 3.2 4.6 3.8 5.2 1.4 2.2 3.3 13.5 5.1 7.4 7.5 2.6 3.5 5.1 4.2 5.5 2.2 2.4 3.3 4.5 2.0 8.5 1.3 4.1 3.1 4.0 7.7 8.0 29.9 6.8 19.1 2.2 11.8 9.7 5.2 2.6 5.4 1.3 1.1 6.5 3.7 3.5 6.5 25.7 3.4 5.1 3.0 3.4 0.2 0.3 6.6 1.0 5.0 2.5 1.7 2.9 4.9 5.5 3.6 3.4 8.8 2.0 0.8 2.8 0.6 2.5 3.8 2.6 3.7 4.0 6.0 4.4 9.5 8.7 6.1 5.0 1.0 16.0 4.0 2.0 0.2 1.8 3.8 5.1 1.5 3.6 2.9 4.0 2.3 2.6 0.1 5.0 5.2 0.8 3.3 3.6 4.8 2.7 4.2 5.6 7.8 6.1 6.0 4.0 2.9 5.0 1.5 10.7 9.0 6.6 11.6 6.7 3.4 5.4 5.4 5.5 4.6 7.1 5.9 15.7 6.9 11.2 2.6 4.7 4.0 4.0 5.5 11.7 5.2 3.8 5.2 5.1 7.4 5.5 4.0 6.8 5.4 24.1 6.4 4.6 266.1 26.3 6.9 10.7 10.6 9.6 31.6 4.5 7.1 33.9 0.0 3.5 3.7 10.4 26.7 35.5 0.2 1.9 3.7 445.2 7.5 43.2 25.8 3.0 2.5 156.1 4.3 5.9 23.4 33.1 16.6 8.8 12.5 14.6 6.5 8.4 33.7 147.1 0.6 2.0 25.7 16.7 742.5 32.0 24.0 23.2 80.6 22.9 4.7 19.6 251.9 189.4 9.4 1.2 29.0 28.7 7.1 0.0 2.1 5.2 9.8 19.7 53.4 32.2 38.2 49.7 3.5 4.8 22.2 48.3 48.3 0.6 8.1 CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 2517.1" "Group enriched" "Detected in many" 7 "Cholangiocytes: 613.4;Hepatocytes: 2420.8" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 16 "classical monocyte: 109.6;myeloid DC: 114.5" "Group enriched" "Detected in many" 22 "dendritic cells: 114.5;monocytes: 109.6" "Group enriched" "Detected in some" 5 "Hep G2: 700.9;THP-1: 688.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" No NA 40000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.92e-4)" 94.9 14.1 0.9 3.2 1.2 27.0 43.6 0.8 1.8 26.6 3.7 82.3 24.0 60.4 7.5 41.1 54.6 272.9 66.1 1.0 1.4 6.7 2517.1 167.8 1.8 2.3 1.2 20.3 8.8 0.7 3.7 8.5 1.5 39.2 12.3 2.9 41.4 36.4 5.2 14.0 27.4 40.4 1.0 41.0 56.1 7.8 1.1 2.5 9.9 9.4 1.0 57.7 17.7 1.1 0.7 4.4 0.0 0.0 90.8 0.6 3.1 0.3 0.0 0.0 0.0 43.5 0.0 0.0 19.4 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.9 700.9 0.0 1.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 40.8 0.1 0.6 0.0 0.0 1.5 6.7 0.0 0.5 0.0 0.1 3.2 0.1 1.1 0.9 0.0 688.0 0.1 0.0 0.4 0.2 0.5 2.2 0.1 1.0 0.0 151.7 0.0 0.0 109.6 0.5 4.5 6.1 1.5 1.1 0.7 5.0 114.5 1.2 0.7 1.1 0.6 0.3 1.6 6.8 0.4 58.0 0.9 1.2 0.8 1.8 1.0 1.4 2.3 1.2 1.5 1.0 1.1 1.1 2.0 16.0 67.6 0.0 11.3 16.7 5.3 6.8 1.2 0.0 1.2 8.1 0.8 613.4 31.5 16.5 0.0 0.5 12.2 0.1 0.0 15.4 79.6 1.0 10.6 8.9 37.5 177.7 0.0 18.7 2.2 57.4 1.1 0.2 6.3 0.0 66.0 2420.8 18.1 0.0 0.0 12.2 4.1 107.3 26.7 197.8 18.6 58.7 39.2 1.0 39.6 10.4 7.2 0.0 0.0 0.9 1.3 98.9 1.8 1.5 0.6 0.9 169.0 0.9 0.0 9.8 9.8 1.0 2.3 20.6 11.6 0.8 16.9 0.9 0.7 2.6 CES4A "CES8, FLJ37464" ENSG00000172824 "Carboxylesterase 4A" Q5XG92 16 66988589-67009758 "Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 16.9;skin 1: 13.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 44.4;Excitatory neurons: 53.6;Oligodendrocytes: 37.6;Respiratory ciliated cells: 47.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.3" "Region enhanced" "Detected in many" "white matter: 10.2" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HDLM-2: 19.1;HMC-1: 5.2;PC-3: 4.5;SiHa: 7.8;SK-BR-3: 5.7;U-266/70: 5.9" "Not detected" "Not detected" HPA035701 Approved Approved Cytosol "Secreted - unknown location" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "HPA035701: AB_10696357" "unprognostic (6.34e-2)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (3.26e-2)" "unprognostic (1.99e-1)" "unprognostic (6.20e-2)" "unprognostic (2.12e-2)" "unprognostic (2.04e-2)" "unprognostic (5.78e-3)" "unprognostic (3.93e-2)" "unprognostic (2.02e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.35e-6)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-3)" 3.6 1.5 1.2 0.8 2.6 1.2 2.5 0.1 2.5 1.0 0.0 0.6 0.8 0.5 3.9 1.0 16.9 0.8 2.4 2.3 1.0 2.6 8.4 1.5 0.7 1.7 0.2 1.0 1.1 3.1 3.6 1.0 1.2 0.9 0.7 0.8 4.3 2.1 4.9 13.6 0.8 0.3 0.0 0.5 1.4 0.8 0.8 0.7 2.7 0.2 0.9 1.2 0.7 10.2 0.2 1.5 0.1 0.0 0.9 0.8 0.0 0.4 0.7 0.1 0.0 0.0 2.3 0.0 0.0 1.5 0.0 0.7 0.0 0.2 0.0 19.1 0.0 0.0 1.2 0.0 0.1 0.0 5.2 1.8 3.5 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 4.5 0.2 0.0 1.1 0.0 0.3 1.4 0.9 7.8 5.7 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 5.9 2.2 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.5 2.5 0.5 0.6 1.0 0.5 0.8 0.0 0.9 0.2 0.0 0.0 3.5 1.2 0.3 0.7 1.2 2.6 0.1 2.5 2.3 1.0 1.7 0.2 1.2 0.0 0.8 10.2 0.4 0.0 11.4 2.0 3.5 5.4 5.7 5.0 3.4 23.1 44.4 7.7 2.8 4.3 7.3 5.5 14.6 4.7 3.9 4.1 1.9 0.9 1.7 9.9 1.4 1.0 9.0 0.0 53.6 1.6 0.9 3.9 3.1 11.1 9.5 4.9 1.1 22.1 5.6 0.0 29.7 1.8 4.1 4.1 2.1 1.2 13.7 3.2 0.0 4.7 5.7 8.3 4.1 6.6 37.6 0.9 9.7 12.8 1.3 3.5 5.8 1.5 47.1 15.3 0.0 1.5 1.8 32.1 11.8 4.1 5.3 4.5 3.3 13.5 3.5 7.5 CFAP251 "CaM-IP4, MGC33630, WDR66" ENSG00000158023 "Cilia and flagella associated protein 251" Q8TBY9 12 121918592-122003927 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.3;testis: 19.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.7;Fibroblasts: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 31.8;hTCEpi: 30.8;hTERT-HME1: 19.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039902, HPA040005" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA039902: AB_10795236, HPA040005: AB_10795160" "unprognostic (4.92e-3)" "unprognostic (9.05e-2)" "unprognostic (7.99e-3)" "prognostic favorable (3.11e-4)" "unprognostic (5.58e-3)" "unprognostic (6.89e-3)" "unprognostic (1.44e-2)" "unprognostic (2.45e-1)" "unprognostic (2.89e-1)" "unprognostic (2.34e-1)" "unprognostic (7.72e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-2)" "unprognostic (4.29e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" 1.1 0.8 1.6 0.3 2.4 0.1 1.3 1.3 1.7 3.5 13.2 0.2 0.1 1.9 4.7 0.3 22.3 1.2 1.3 2.4 3.9 2.7 1.4 3.0 0.6 5.5 6.6 2.2 1.7 2.9 6.5 0.9 3.6 0.7 0.1 4.6 1.1 1.6 0.3 1.5 0.2 0.6 2.7 1.7 0.4 19.9 4.1 0.5 4.7 0.4 0.9 0.3 1.3 1.6 4.7 0.4 0.4 0.2 0.5 0.5 0.5 0.3 2.5 1.2 3.0 0.3 1.4 0.2 3.7 0.2 0.7 0.9 0.3 31.8 4.4 0.2 0.5 0.2 0.6 0.3 3.7 0.1 8.6 1.8 30.8 2.4 19.9 0.7 1.3 0.5 7.5 0.1 1.9 0.9 0.3 0.6 0.4 0.4 0.2 0.4 0.8 0.0 5.4 0.5 2.5 0.1 0.2 0.1 0.2 0.8 0.9 0.1 1.0 2.5 3.9 0.5 0.5 0.5 0.2 3.8 2.9 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.0 1.6 2.4 1.3 1.7 2.4 3.9 5.5 6.6 3.6 2.7 4.1 1.6 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 CFAP36 "BARTL1, CCDC104, MGC15407" ENSG00000163001 "Cilia and flagella associated protein 36" Q96G28 2 55519604-55545079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1342.4;Late spermatids: 262.5;Spermatocytes: 346.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008994, HPA017061" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli fibrillar center, Nuclear bodies" Cytosol "HPA008994: AB_2275429, HPA017061: AB_1846129" "unprognostic (8.11e-2)" "unprognostic (3.21e-3)" "unprognostic (1.24e-1)" "unprognostic (3.36e-2)" "unprognostic (7.98e-2)" "unprognostic (3.68e-1)" "unprognostic (4.65e-3)" "unprognostic (7.79e-2)" "unprognostic (1.51e-2)" "unprognostic (1.58e-2)" "unprognostic (3.66e-3)" "unprognostic (7.63e-2)" "unprognostic (8.57e-3)" "unprognostic (4.94e-2)" "unprognostic (3.35e-2)" "unprognostic (1.56e-3)" "unprognostic (2.96e-1)" 39.1 42.7 72.7 20.2 74.8 16.5 48.9 61.8 98.8 49.8 82.8 52.3 15.1 47.1 77.0 21.9 62.3 40.9 35.7 75.0 78.5 63.2 17.7 33.9 21.7 71.8 70.4 58.9 33.6 78.0 106.7 20.6 72.1 41.6 23.2 124.3 28.7 45.0 19.2 18.8 25.2 37.4 65.9 18.2 42.1 145.2 73.6 22.8 78.0 27.1 19.7 40.7 33.6 70.1 59.5 47.3 50.2 66.3 64.4 119.4 30.4 36.6 73.4 54.9 46.6 34.6 21.2 21.3 82.3 48.9 81.9 38.4 39.3 51.4 67.7 51.9 76.2 31.0 43.9 38.1 70.0 59.4 38.4 58.1 82.7 74.0 92.1 146.8 58.9 42.5 40.1 18.2 66.1 44.4 35.7 67.5 25.2 38.7 44.8 27.2 59.7 21.7 112.1 33.7 74.1 36.6 49.4 25.6 68.5 26.2 42.1 19.7 32.5 57.6 33.7 58.5 50.8 29.9 14.2 7.3 94.0 26.7 26.8 15.5 4.3 13.6 18.3 5.0 35.4 16.9 50.6 29.6 5.8 11.7 41.1 26.0 5.2 12.3 6.4 13.5 30.5 15.9 72.7 74.8 61.8 98.8 75.0 78.5 71.8 70.4 72.1 65.9 73.6 70.1 51.3 48.1 30.6 15.7 14.5 0.0 52.6 0.0 22.2 39.6 48.7 77.2 37.9 38.6 27.2 35.0 8.4 14.3 14.8 6.4 92.0 61.9 1342.4 184.4 51.8 42.9 17.0 21.0 51.6 60.7 27.0 44.7 21.9 36.3 39.1 27.1 42.1 10.7 23.6 23.5 41.1 12.2 0.0 8.7 0.0 262.5 75.2 12.8 0.0 14.0 16.9 145.0 16.5 21.6 13.3 37.0 11.5 67.7 11.4 41.3 7.6 146.9 99.1 92.4 59.2 43.0 43.4 346.0 29.8 16.1 0.0 7.8 24.7 36.0 9.9 35.6 CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859664-863641 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1496.7;breast: 993.2" "Group enriched" "Detected in many" 6 "Fibroblasts: 9365.5;Leydig cells: 5032.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 297.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 297.6" "Group enriched" "Detected in many" 5 "ASC diff: 197.4;THP-1: 342.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 732000000 4400000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" 1496.7 33.3 1.5 9.6 1.6 10.7 993.2 1.2 2.4 597.4 3.7 324.8 23.5 58.4 2.4 212.8 258.0 9.6 854.2 1.7 2.3 18.1 8.7 363.3 2.1 3.3 2.3 74.3 41.4 1.7 9.0 14.5 3.6 277.8 10.9 0.6 247.3 6.3 197.0 488.6 248.4 4.0 2.6 28.6 263.8 51.8 2.9 3.6 332.3 26.9 0.8 848.3 729.8 5.8 3.9 5.2 0.6 2.2 197.4 26.2 9.5 0.8 0.0 0.0 0.0 0.8 0.4 0.2 5.7 0.0 0.5 3.0 1.8 0.5 0.0 5.7 14.5 0.5 12.3 3.8 3.6 2.5 4.9 8.7 0.2 0.1 0.0 0.8 0.0 4.5 11.9 0.9 0.0 2.6 0.6 49.2 1.0 4.5 16.1 1.3 0.5 5.2 0.3 1.2 1.8 1.8 5.5 1.9 0.5 0.6 7.5 342.2 0.4 0.2 5.1 2.9 0.6 7.8 4.7 0.4 0.2 20.8 0.2 297.6 41.2 127.8 8.4 55.5 13.2 5.7 4.2 10.2 14.5 1.4 9.7 9.7 112.0 1.3 57.3 1.8 4.7 37.8 1.5 1.6 1.2 2.4 1.7 2.3 3.3 2.3 3.6 2.6 2.9 5.8 857.8 9.6 23.3 0.0 19.2 785.5 49.0 10.1 17.1 2.9 107.3 120.1 55.5 21.5 30.9 18.4 2.1 36.6 40.0 33.1 11.7 7.7 27.1 23.1 593.3 114.8 4.2 8.2 0.2 0.0 32.9 9365.5 113.6 15.9 17.1 0.9 30.4 2.6 272.4 1.7 0.4 8.7 0.0 424.7 1145.2 89.6 5032.4 442.5 642.1 4.7 303.6 1.3 21.6 0.0 0.1 2.9 64.8 283.2 41.0 19.7 4.3 3.4 28.4 6.5 0.0 414.3 530.2 11.4 21.3 28.6 735.9 34.3 82.8 1.2 21.0 233.2 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109801999 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1098.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 592.5;Muller glia cells: 147.8;Proximal tubular cells: 223.6" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 106.1;Hep G2: 179.8;HSkMC: 67.4;RPTEC TERT1: 190.6" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 12000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" 45.1 50.2 8.1 12.6 8.2 0.1 17.4 7.7 13.2 36.8 10.4 7.4 38.0 39.2 80.3 9.3 74.0 73.0 25.0 8.3 9.6 224.9 1098.8 50.7 8.9 15.6 10.2 32.1 26.0 3.1 8.4 24.1 10.7 8.3 6.4 53.0 15.0 26.7 3.9 2.7 22.3 24.3 10.5 33.1 14.4 8.8 9.2 2.3 14.5 4.6 7.5 34.1 8.3 10.6 0.0 0.6 0.0 0.3 0.0 0.2 0.1 1.5 1.4 0.1 0.2 0.0 106.1 0.0 32.9 0.0 0.5 0.0 0.0 0.0 0.0 34.8 0.7 0.0 0.4 179.8 6.2 0.3 0.0 67.4 0.0 0.1 0.0 3.6 4.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 190.6 0.5 0.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.0 0.1 18.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 8.2 7.7 13.2 8.3 9.6 15.6 10.2 10.7 10.5 9.2 10.6 48.1 12.8 50.9 3.6 4.0 1.0 12.2 15.2 0.6 3.4 2.1 5.6 2.3 108.7 36.2 64.4 2.1 0.1 0.3 1.7 31.3 69.3 0.2 34.1 46.4 57.7 0.0 2.7 0.3 30.9 0.2 34.3 8.2 33.6 3.8 72.1 55.0 592.5 0.7 1.7 0.2 1.9 0.0 16.7 1.5 0.8 16.8 2.0 0.0 4.7 1.6 147.8 0.0 0.0 0.3 30.8 2.4 0.0 0.0 3.8 17.0 223.6 8.4 7.3 0.0 1.3 9.4 1.6 0.5 1.9 1.1 0.3 3.4 18.5 4.1 12.6 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.6;intestine: 42.7;pancreas: 210.7" "Group enriched" "Detected in many" 4 "Ductal cells: 485.4;Ionocytes: 252.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "CACO-2: 29.5;MOLT-4: 98.9;U-266/70: 49.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.0 0.5 4.7 2.0 0.0 0.4 0.7 1.3 8.5 0.0 42.7 36.2 1.1 1.1 0.8 2.2 54.6 0.1 0.3 0.7 2.1 1.6 8.2 0.0 1.1 0.7 0.0 210.7 0.2 0.1 0.6 0.7 2.2 40.7 0.0 21.5 0.5 0.0 1.9 19.9 2.0 1.7 0.0 3.1 1.7 1.0 0.1 0.1 0.0 0.3 0.7 0.0 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 98.9 0.1 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 49.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.7 1.3 0.3 0.7 1.1 0.7 0.7 1.7 1.0 2.9 0.0 6.4 65.6 0.0 0.5 0.0 2.0 2.6 0.0 0.5 0.5 0.0 2.4 55.8 17.8 0.0 0.0 0.0 0.0 45.8 0.0 485.4 3.2 9.6 1.2 0.4 7.2 0.0 2.2 4.5 0.0 0.3 4.1 19.8 1.3 0.1 0.0 0.4 0.0 0.0 1.1 13.9 252.3 0.0 0.0 2.6 0.3 0.1 0.0 1.0 6.7 0.5 0.0 0.5 23.8 14.8 86.4 0.0 0.0 4.0 8.6 0.0 5.6 0.0 0.0 0.0 1.6 2.2 0.5 0.0 0.0 0.0 0.3 0.1 87.3 5.8 CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Distal enterocytes: 173.2;Paneth cells: 108.7;Proximal enterocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 91.4;CAPAN-2: 59.1;OE19: 58.6;RT4: 44.0" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: AB_10600208, HPA027587: AB_10601884, HPA027657: AB_10611527" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.74e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (4.61e-1)" "unprognostic (2.11e-2)" "unprognostic (2.96e-3)" "unprognostic (7.10e-2)" "prognostic favorable (5.84e-10)" "unprognostic (2.66e-1)" "unprognostic (3.00e-1)" "unprognostic (8.28e-2)" "unprognostic (2.10e-2)" 5.8 1.1 1.9 6.0 3.3 0.4 9.0 8.5 3.3 4.9 6.5 37.2 52.7 1.4 1.5 8.6 13.2 13.6 0.6 2.0 3.7 12.2 32.1 27.3 0.4 5.5 3.0 2.0 24.2 32.1 3.7 1.6 5.6 10.1 25.1 3.7 21.1 7.0 0.2 17.9 56.4 1.5 1.7 0.4 30.4 6.6 3.4 0.7 4.9 0.1 2.3 8.3 6.2 6.7 28.9 3.2 2.7 4.6 0.0 0.0 35.4 0.1 0.1 0.8 0.9 91.4 59.1 1.3 9.4 0.0 4.9 27.0 8.6 5.0 0.6 17.3 6.0 2.4 1.3 1.8 0.0 0.4 3.6 0.0 1.0 1.3 0.7 0.0 0.3 7.8 1.2 8.1 0.0 26.8 5.0 0.6 22.9 58.6 2.5 5.4 2.8 4.3 17.9 44.0 8.9 4.4 1.8 27.1 1.0 10.3 33.5 0.3 0.5 0.3 8.3 0.5 1.2 7.7 8.4 5.2 0.3 3.3 2.4 0.2 0.1 0.0 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 1.9 3.3 8.5 3.3 2.0 3.7 5.5 3.0 5.6 1.7 3.4 6.7 0.1 118.6 33.3 2.3 0.2 0.3 3.3 5.9 0.6 4.3 14.9 9.1 0.7 24.3 22.4 3.7 0.0 3.5 0.5 173.2 0.0 21.5 0.3 13.8 2.1 0.6 10.3 2.7 0.8 25.4 0.3 2.3 54.6 27.3 0.0 0.5 0.0 29.6 0.3 0.0 10.4 32.7 8.2 0.0 0.4 1.2 0.6 0.5 3.6 0.0 2.1 13.5 0.0 3.5 11.7 49.5 108.7 0.7 0.5 11.9 88.7 3.0 46.8 1.5 0.0 0.1 1.0 1.5 6.9 4.2 1.8 0.4 0.6 1.8 27.2 18.3 CHAC1 MGC4504 ENSG00000128965 "ChaC glutathione specific gamma-glutamylcyclotransferase 1" Q9BUX1 15 40952962-40956512 "Enzymes, Predicted intracellular proteins" "Apoptosis, Neurogenesis, Notch signaling pathway, Unfolded protein response" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 68.6;skeletal muscle: 68.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 35.2;Exocrine glandular cells: 27.8;Gastric mucus-secreting cells: 33.6;Pancreatic endocrine cells: 19.3;Plasma cells: 21.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 109.5;HHSteC: 80.7;hTCEpi: 130.8;SK-MEL-30: 95.0;U-266/70: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA042708, HPA043505" Approved Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" Mitochondria "HPA042708: AB_2678125, HPA043505: AB_2678518" "unprognostic (6.04e-3)" "unprognostic (2.81e-2)" "unprognostic (7.47e-2)" "unprognostic (2.84e-3)" "unprognostic (6.57e-3)" "unprognostic (2.00e-2)" "unprognostic (5.59e-2)" "unprognostic (2.43e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" "unprognostic (3.11e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.23e-7)" "unprognostic (1.37e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-2)" "unprognostic (3.91e-2)" 9.1 0.6 12.3 1.4 12.0 1.8 0.9 11.1 30.7 2.1 7.1 1.9 2.0 0.7 1.5 23.3 1.7 1.8 2.4 11.4 16.6 4.0 11.5 2.0 0.9 13.0 14.5 0.7 68.6 1.4 1.9 0.8 16.9 1.3 0.8 1.1 5.1 1.0 68.4 1.6 1.4 0.8 12.6 0.9 14.8 0.7 17.6 0.5 1.5 11.7 3.0 4.3 3.7 16.6 9.1 6.0 1.5 27.2 4.3 3.2 11.1 53.5 109.5 5.8 15.5 15.1 2.2 2.8 4.1 4.8 17.2 6.0 12.0 4.4 4.1 10.4 2.5 2.5 1.6 0.0 80.7 7.3 0.1 36.1 130.8 17.1 23.2 1.8 5.4 62.3 7.7 12.5 4.8 5.5 5.3 0.1 4.9 31.0 21.3 4.8 0.1 12.8 3.0 3.5 5.3 7.9 1.6 9.5 95.0 3.3 3.6 51.1 1.8 1.3 16.1 1.5 9.4 81.1 19.0 11.0 4.8 10.3 12.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 12.3 12.0 11.1 30.7 11.4 16.6 13.0 14.5 16.9 12.6 17.6 16.6 6.2 0.0 2.0 0.3 3.1 2.8 3.8 11.5 3.4 2.6 2.2 2.4 4.6 4.3 6.5 0.0 2.1 0.3 2.6 8.0 35.2 6.4 0.1 1.8 0.4 2.7 3.5 3.2 1.3 27.8 0.3 0.6 33.6 2.1 0.0 0.4 1.8 0.7 0.4 0.0 1.5 8.0 6.1 0.3 1.5 0.0 0.3 0.8 5.4 0.0 1.0 0.5 0.0 0.5 0.2 19.3 2.3 0.0 21.4 6.5 0.8 0.3 3.3 0.4 0.0 0.3 3.2 1.1 1.1 1.5 4.3 3.4 1.6 0.5 4.8 14.6 CHD5 ENSG00000116254 "Chromodomain helicase DNA binding protein 5" Q8TDI0 1 6101787-6180321 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 59.0;pituitary gland: 57.3;testis: 31.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 84.3;Early spermatids: 217.8;Excitatory neurons: 80.4;Horizontal cells: 225.4;Inhibitory neurons: 56.2;Late spermatids: 113.2;Rod photoreceptor cells: 49.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 12.9;U-2 OS: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015809 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear speckles" Cytosol "HPA015809: " "unprognostic (5.03e-4)" "unprognostic (1.89e-1)" "unprognostic (2.47e-3)" "unprognostic (9.40e-6)" "unprognostic (1.91e-2)" "unprognostic (2.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.95e-2)" "unprognostic (6.64e-4)" "unprognostic (1.34e-1)" "unprognostic (1.34e-4)" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" 0.2 4.1 31.8 0.2 40.1 0.0 0.1 0.0 59.0 0.4 0.0 1.1 0.2 0.4 0.0 0.3 0.4 0.1 0.4 34.3 13.6 2.4 0.1 0.3 0.0 3.9 11.1 0.5 0.4 0.9 57.3 0.0 4.4 0.9 0.2 7.9 0.2 2.2 0.2 0.3 0.4 0.1 0.9 0.1 1.0 31.8 10.2 0.3 0.1 0.0 0.0 0.7 0.6 31.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 1.2 0.0 0.1 0.2 1.1 0.0 0.0 0.0 0.0 12.9 0.2 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.8 40.1 0.0 59.0 34.3 13.6 3.9 11.1 4.4 0.9 10.2 31.1 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 0.0 84.3 0.1 0.3 2.1 0.0 0.0 3.7 12.5 0.0 0.1 0.2 0.0 0.0 217.8 0.0 0.2 0.6 0.0 0.0 80.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 225.4 56.2 0.0 0.0 0.0 0.3 113.2 0.9 0.1 0.0 2.8 0.0 2.0 0.0 4.5 3.7 0.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 49.9 0.0 0.2 0.5 4.5 17.8 0.0 0.4 0.0 0.1 0.1 0.0 0.0 CHD8 "DUPLIN, HELSNF1, KIAA1564" ENSG00000100888 "Chromodomain helicase DNA binding protein 8" Q9HCK8 14 21385194-21456126 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Chromatin regulator, DNA-binding, Helicase, Hydrolase, Repressor" "Autism, Autism spectrum disorder, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052186, HPA076133" Enhanced Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA052186: AB_2681754, HPA076133: " "unprognostic (3.45e-1)" "unprognostic (9.71e-2)" "unprognostic (3.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.14e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.31e-2)" "unprognostic (9.22e-2)" "prognostic favorable (8.35e-4)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (2.54e-3)" "unprognostic (2.88e-1)" "unprognostic (9.24e-2)" "unprognostic (2.51e-1)" "unprognostic (8.07e-3)" 12.5 11.9 11.2 13.5 12.5 35.3 14.8 16.3 13.2 12.4 10.5 14.0 9.4 14.8 11.1 14.9 12.9 10.1 12.0 11.1 12.2 11.7 9.6 13.7 18.0 11.4 11.6 17.1 13.6 22.3 13.1 11.7 11.1 13.2 12.3 14.8 13.6 12.1 15.7 22.3 14.7 14.8 11.5 15.8 14.2 12.9 12.5 25.4 14.8 12.7 17.5 12.8 12.9 13.6 31.2 39.6 43.6 20.7 27.7 23.6 24.9 24.4 28.4 36.5 35.4 35.0 26.3 51.4 14.8 33.1 28.4 37.2 54.9 35.1 46.0 39.3 24.2 46.3 27.6 43.5 25.7 64.6 40.4 32.8 27.2 40.9 29.7 28.6 33.4 40.2 32.4 26.7 28.0 33.9 46.1 26.0 33.4 30.9 34.3 42.0 32.9 17.4 27.3 57.9 30.9 30.7 37.5 29.8 21.8 39.7 20.7 30.5 36.4 29.2 23.0 17.8 29.1 30.3 38.4 50.3 12.1 23.2 29.6 9.1 3.8 9.8 5.5 3.8 6.4 4.2 4.9 5.6 2.7 11.2 5.0 4.4 7.9 7.8 6.7 6.1 4.7 2.7 11.2 12.5 16.3 13.2 11.1 12.2 11.4 11.6 11.1 11.5 12.5 13.6 27.6 38.5 56.3 27.4 32.2 12.6 11.3 15.9 23.3 33.3 21.9 22.6 19.6 24.3 32.6 33.1 27.1 14.7 40.0 16.8 1.9 21.8 3.4 32.5 37.9 25.5 27.1 27.8 41.0 23.6 12.3 24.0 27.5 39.5 28.4 41.7 13.9 14.9 17.5 23.5 40.2 16.0 8.2 20.1 9.3 4.1 16.1 25.3 10.6 20.6 27.1 18.9 32.0 29.7 33.1 26.5 13.9 17.7 32.4 16.1 12.0 7.4 28.8 24.3 0.0 32.1 26.2 29.2 25.1 24.6 16.6 12.3 31.4 34.1 16.8 12.7 CHDH ENSG00000016391 "Choline dehydrogenase" Q8NE62 3 53812335-53846419 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 37.6;liver: 35.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 52.9;Hepatocytes: 51.8;Proximal enterocytes: 70.1;Proximal tubular cells: 87.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "basophil: 3.1;T-reg: 1.3" "Group enriched" "Detected in many" 17 "granulocytes: 3.1;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 11.4;Hep G2: 35.8;OE19: 25.3;T-47d: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036633, HPA058130" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036633: AB_10670841, HPA058130: AB_2683615" "unprognostic (3.40e-3)" "unprognostic (1.17e-2)" "unprognostic (2.26e-3)" "unprognostic (7.17e-3)" "unprognostic (9.15e-2)" "unprognostic (1.17e-3)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (2.75e-1)" "unprognostic (4.35e-3)" "unprognostic (4.57e-2)" "unprognostic (5.12e-2)" "prognostic favorable (1.88e-8)" "unprognostic (3.37e-2)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (2.29e-2)" 0.6 2.8 13.6 1.8 14.3 0.6 7.3 12.5 11.4 3.7 16.5 8.9 8.4 2.7 1.4 0.9 2.6 2.7 2.4 11.3 10.9 37.6 35.8 2.4 1.0 14.5 13.9 1.3 16.4 8.3 7.8 0.4 10.1 5.8 9.2 1.5 15.0 1.0 3.9 2.4 14.7 0.9 10.3 0.5 8.0 6.9 15.9 0.2 2.6 1.2 1.2 0.4 0.9 12.0 0.4 4.6 1.2 0.1 0.0 0.0 5.2 0.3 0.5 0.0 0.0 11.4 0.8 0.4 0.8 0.8 0.1 0.0 7.4 0.0 0.0 0.0 4.0 0.0 1.7 35.8 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.6 0.0 0.0 5.7 0.7 0.0 6.9 0.0 0.1 7.2 25.3 0.8 0.0 1.8 8.2 5.1 4.0 3.0 4.0 1.8 0.1 0.0 0.9 11.2 0.1 0.0 0.0 0.8 0.2 1.0 1.0 1.6 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 13.6 14.3 12.5 11.4 11.3 10.9 14.5 13.9 10.1 10.3 15.9 12.0 0.6 3.2 6.8 19.6 1.3 6.6 5.6 1.1 1.2 23.8 23.5 19.8 11.3 52.9 5.9 11.0 14.6 3.7 0.4 16.6 7.9 19.4 28.9 3.2 11.0 1.4 47.9 0.0 2.4 13.8 2.3 2.3 21.4 9.4 7.0 2.2 1.4 51.8 0.3 1.7 3.5 38.9 0.0 1.9 2.5 46.2 5.9 2.6 3.6 1.0 0.1 18.8 0.0 27.2 5.2 8.0 15.1 15.4 5.3 19.8 70.1 87.8 3.8 13.4 0.0 1.0 3.4 15.1 2.3 0.7 5.3 0.8 2.4 2.0 45.4 2.2 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625665-125676255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;lymphoid tissue: 20.7;seminal vesicle: 29.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Erythroid cells: 34.5;Extravillous trophoblasts: 35.6;Spermatocytes: 48.9;Spermatogonia: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 1.7;T-cells: 6.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044364 Supported Nucleoplasm,Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA044364: AB_2678913" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favorable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavorable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 1.6 1.3 0.7 8.2 1.0 25.7 2.6 0.6 1.3 1.7 0.5 7.9 6.8 1.7 6.7 4.1 1.1 1.7 0.9 0.7 0.9 2.2 2.1 1.3 14.9 0.7 0.8 1.8 2.0 13.2 1.7 4.8 0.8 1.6 8.7 0.7 1.5 29.8 0.6 3.6 7.3 3.4 0.6 2.2 2.6 8.9 1.2 20.7 1.0 1.3 13.9 3.3 2.1 0.8 48.5 37.0 81.1 47.4 13.5 28.9 35.7 61.1 28.7 41.6 40.1 88.0 100.3 120.7 63.5 24.9 53.7 52.6 54.2 33.2 50.1 81.4 24.8 224.2 27.2 44.7 4.3 121.1 39.6 15.7 6.0 47.6 36.0 19.9 44.7 84.1 117.3 102.7 51.4 23.8 181.3 65.0 86.1 77.1 33.2 104.7 74.4 67.2 37.9 63.2 50.5 53.6 45.2 35.4 15.2 57.3 93.9 40.6 28.4 51.0 47.3 29.6 60.8 21.9 45.4 187.5 20.5 86.6 67.6 1.7 0.2 0.0 0.4 0.1 0.2 0.7 1.6 0.4 0.6 0.3 0.4 0.3 1.1 0.3 0.1 0.7 6.2 0.4 0.7 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.8 0.6 1.2 0.8 1.1 3.2 0.5 1.6 5.5 6.2 3.9 5.8 5.2 1.7 3.9 6.0 4.6 32.9 4.1 7.3 0.0 17.3 6.0 4.5 3.9 3.4 7.8 5.5 8.0 3.5 1.8 34.5 3.3 1.1 35.6 5.3 6.1 9.9 0.0 21.1 3.6 1.2 11.1 0.0 2.5 9.2 2.0 0.0 5.2 3.1 1.5 3.2 0.0 2.8 3.2 2.8 3.1 1.5 1.6 2.9 3.9 1.2 17.7 3.1 8.0 9.4 2.5 1.7 0.0 3.1 7.8 48.9 49.8 9.5 4.8 7.8 5.1 4.8 16.7 3.0 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatogonia: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 4.5 6.2 2.4 8.8 2.5 15.4 5.8 2.4 3.7 5.0 2.8 8.8 6.3 4.1 7.3 7.2 3.7 4.7 4.2 2.3 2.8 4.5 6.3 4.4 12.1 2.6 2.6 8.2 2.3 1.3 2.7 7.8 2.8 4.1 10.9 0.4 3.2 3.8 1.3 6.7 7.0 4.8 2.6 6.7 4.1 8.5 2.8 9.4 3.3 1.1 12.0 6.8 5.0 2.9 30.7 9.7 31.1 32.4 10.1 42.7 18.7 15.2 19.9 18.7 27.8 29.1 21.8 36.3 13.0 11.5 21.6 32.1 42.7 29.0 25.0 24.6 31.2 45.3 25.5 46.2 9.4 33.4 38.0 18.6 13.5 25.0 23.0 14.1 25.4 29.4 30.5 33.9 19.8 39.2 24.6 61.5 40.6 41.3 21.6 52.6 18.2 42.7 17.1 11.2 17.8 9.7 16.7 31.4 17.4 22.8 22.6 32.2 7.8 17.1 19.4 14.3 9.1 21.8 28.3 65.4 17.1 34.9 21.0 9.9 4.0 1.2 1.1 8.1 2.4 11.9 2.1 2.1 8.2 7.8 4.0 2.6 0.6 3.4 4.1 6.1 2.8 3.6 2.4 2.5 2.4 3.7 2.3 2.8 2.6 2.6 2.8 2.6 2.8 2.9 2.3 9.6 4.8 2.9 5.5 6.4 5.3 8.3 8.6 1.1 3.2 3.9 1.8 0.0 5.0 1.8 0.0 15.4 1.1 3.8 0.0 1.8 7.0 2.9 10.1 3.0 1.2 11.2 2.9 1.4 13.6 12.4 5.1 7.0 3.8 7.4 2.5 1.3 9.7 0.0 1.2 5.3 8.2 2.4 8.5 1.2 6.2 5.1 1.8 2.8 3.9 0.8 6.2 0.0 1.0 1.0 4.7 4.5 11.4 2.7 3.0 3.9 2.9 1.1 0.0 10.2 3.0 6.7 31.2 8.3 2.3 3.4 3.3 5.7 10.0 4.5 CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 232.4;brain: 239.4;liver: 447.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 88.7;Ductal cells: 88.9;Hepatocytes: 61.8;Hofbauer cells: 317.5" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 495 "neutrophil: 470.4" "Lineage enriched" "Detected in single" 495 "granulocytes: 470.4" "Cell line enhanced" "Detected in some" "ASC diff: 322.9;ASC TERT1: 712.9;HSkMC: 637.0;THP-1: 1068.4;U-138 MG: 303.5;U-87 MG: 303.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 10 "olfactory bulb: 16.0" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 180000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 79.8 2.0 58.9 138.9 75.9 232.4 62.8 55.3 94.7 30.5 56.8 6.5 0.4 19.5 1.0 14.4 23.4 3.0 9.8 47.4 129.6 60.9 447.8 38.4 32.4 239.4 112.8 6.6 13.8 0.2 134.5 10.1 135.6 13.7 2.0 50.9 99.4 0.9 21.0 75.6 16.8 6.8 70.0 13.9 9.7 1.0 156.4 12.4 15.0 1.0 36.9 97.8 9.1 70.8 0.8 0.0 0.0 0.3 322.9 712.9 0.0 0.0 0.2 0.0 0.0 75.3 0.2 0.1 1.2 0.4 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.3 0.3 0.3 637.0 0.0 1.9 0.3 30.8 0.0 0.0 0.0 1.0 0.2 0.3 0.0 5.8 2.7 0.0 0.0 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.2 0.0 1068.4 0.0 303.5 1.6 0.0 0.4 2.3 41.9 0.3 303.7 1.2 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.4 0.0 0.9 0.0 0.0 1.3 58.9 75.9 55.3 94.7 47.4 129.6 239.4 112.8 135.6 70.0 156.4 70.8 0.7 6.4 42.8 20.5 0.1 4.2 47.1 88.7 0.0 0.1 29.8 21.5 1.0 2.8 17.3 27.6 0.0 1.3 0.6 0.0 0.0 88.9 0.0 4.8 2.2 2.1 0.0 0.4 1.1 0.0 1.1 18.6 0.0 7.2 0.0 0.0 0.0 61.8 317.5 0.0 0.1 0.0 6.1 0.8 0.4 0.0 0.9 23.7 14.2 0.0 1.0 45.1 0.0 0.0 0.1 2.0 0.0 0.0 1.4 4.2 0.0 0.2 3.4 2.8 0.0 1.0 2.3 0.0 0.0 1.5 1.1 0.8 0.9 0.0 0.0 2.2 CHMP4A "C14orf123, HSPC134, VPS32A" ENSG00000254505 "Charged multivesicular body protein 4A" Q9BY43 14 24209615-24213830 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068473 Approved NA NA 1400000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA068473: AB_2685994" "unprognostic (4.33e-3)" "unprognostic (3.76e-2)" "unprognostic (4.29e-2)" "unprognostic (5.45e-2)" "unprognostic (4.29e-1)" "unprognostic (1.25e-1)" "unprognostic (1.74e-4)" "unprognostic (2.02e-3)" "unprognostic (9.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (3.91e-8)" "unprognostic (3.30e-1)" "unprognostic (3.42e-1)" "unprognostic (7.37e-2)" "unprognostic (6.90e-2)" 58.8 39.5 73.9 49.3 77.3 38.5 51.4 74.2 109.3 39.1 68.5 59.2 39.4 33.6 79.0 50.5 45.2 35.8 46.9 71.2 73.4 52.4 53.5 36.1 72.6 76.6 75.6 30.8 42.5 72.9 23.0 33.9 76.5 51.0 64.5 15.5 31.5 60.6 20.1 51.6 43.6 51.6 76.8 51.5 45.8 16.5 78.1 70.4 43.4 27.4 84.9 47.7 32.0 77.7 48.7 100.5 43.8 49.1 75.4 67.9 59.7 52.9 62.6 53.0 60.7 46.6 114.9 79.0 48.5 80.6 49.8 56.4 47.5 84.7 58.8 142.6 25.6 64.7 91.6 207.4 131.8 101.1 69.9 69.1 121.6 43.9 168.4 60.8 72.3 84.6 68.2 119.7 107.1 136.1 98.0 93.5 29.0 123.3 83.0 71.9 37.5 86.7 99.3 128.4 28.4 34.3 112.7 101.8 73.8 49.8 65.7 90.2 49.4 33.0 40.0 42.7 47.2 117.1 133.2 86.4 31.2 71.7 71.3 144.3 152.2 103.4 123.4 195.6 132.9 182.8 131.8 138.5 179.9 169.3 101.6 109.9 42.6 138.4 193.6 190.0 185.2 171.6 73.9 77.3 74.2 109.3 71.2 73.4 76.6 75.6 76.5 76.8 78.1 77.7 74.2 16.0 33.3 13.4 78.6 52.6 76.0 154.8 18.8 31.8 66.7 65.7 2.1 92.9 86.3 62.5 64.6 93.4 111.4 50.0 97.8 116.0 11.0 49.1 52.5 58.8 39.2 53.7 14.3 82.3 84.0 39.3 25.5 53.2 76.5 41.1 67.5 73.1 162.5 25.2 12.6 69.9 99.7 94.8 90.3 19.1 66.8 80.1 69.4 11.2 202.6 64.7 178.2 12.1 15.5 76.0 66.7 48.5 44.8 76.1 144.9 159.3 72.2 24.2 98.6 40.6 58.1 20.4 18.3 32.3 78.8 120.7 102.8 43.8 79.7 70.4 CHP2 ENSG00000166869 "Calcineurin like EF-hand protein 2" O43745 16 23755026-23758935 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 305.0;skin 1: 149.7" "Group enriched" "Detected in some" 5 "Distal enterocytes: 345.0;Paneth cells: 274.0;Proximal enterocytes: 654.2;Undifferentiated cells: 205.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 7.3;hTERT-RPE1: 10.2;NB-4: 8.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055198, CAB072806" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nucleoli, Cytosol" "CAB072806: , HPA055198: " "unprognostic (4.82e-1)" "unprognostic (3.40e-1)" "unprognostic (4.93e-2)" "unprognostic (1.01e-2)" "unprognostic (8.85e-2)" "unprognostic (3.54e-1)" "unprognostic (4.54e-2)" "unprognostic (1.47e-1)" "unprognostic (1.38e-1)" "unprognostic (5.31e-2)" "unprognostic (4.70e-2)" "unprognostic (1.44e-5)" "unprognostic (2.21e-1)" "unprognostic (5.97e-2)" "unprognostic (7.84e-2)" "unprognostic (9.01e-2)" 0.4 0.2 1.1 3.8 1.1 2.2 4.3 3.6 1.3 14.0 0.0 146.7 305.0 0.9 1.1 0.6 0.9 0.4 0.4 0.7 1.6 4.1 0.7 0.6 0.8 0.5 0.1 0.4 0.5 0.1 0.0 1.4 0.9 3.8 147.4 1.3 0.8 4.5 1.2 149.7 250.5 6.5 0.1 0.3 1.1 7.3 0.9 0.5 0.6 0.2 0.4 9.0 4.2 2.9 1.0 2.2 0.5 0.6 1.2 1.3 1.2 2.9 1.1 0.3 1.0 0.5 2.3 0.4 0.9 2.5 1.2 1.4 0.4 2.9 0.6 0.7 0.2 0.5 4.1 1.6 1.7 0.3 0.7 0.9 0.8 2.5 7.3 10.2 1.1 0.3 1.2 1.0 1.2 0.1 0.1 8.7 0.3 0.5 2.1 0.2 0.1 1.4 1.1 0.7 0.6 0.7 0.8 0.2 0.0 0.6 0.2 0.2 1.3 0.5 0.6 0.7 0.1 0.4 0.1 0.2 0.0 0.5 0.5 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.1 0.1 0.0 0.0 1.1 1.1 3.6 1.3 0.7 1.6 0.5 0.1 0.9 0.1 0.9 2.9 0.0 0.0 0.0 0.0 0.0 10.3 8.7 6.1 0.0 0.0 0.0 0.1 0.1 0.0 24.4 1.8 0.0 0.9 0.0 345.0 0.0 0.0 0.6 1.3 0.5 0.2 9.1 0.0 0.0 0.0 4.1 0.2 0.0 3.6 4.5 0.7 0.0 0.0 0.1 0.0 0.0 70.0 12.2 0.0 1.6 0.5 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 274.0 0.0 0.0 2.5 654.2 12.9 4.4 0.0 0.0 0.0 0.3 0.0 0.2 0.0 67.5 0.7 0.2 0.2 205.4 29.9 CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 27.0;prostate: 29.6;salivary gland: 28.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Breast myoepithelial cells: 3.6;Excitatory neurons: 8.7;Inhibitory neurons: 7.8;Intestinal goblet cells: 3.2;Melanocytes: 3.6;Oligodendrocyte precursor cells: 3.0;Prostatic glandular cells: 4.4" "Cancer enriched" "Detected in some" 16 "prostate cancer: 27.9" "Group enriched" "Detected in many" 178 "amygdala: 12.4;basal ganglia: 18.7;cerebral cortex: 27.0;hippocampal formation: 22.6;white matter: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "MCF7: 3.7;OE19: 12.3" "Low region specificity" "Detected in many" HPA014101 Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA014101: AB_1854210" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-1)" "unprognostic (8.57e-4)" "unprognostic (4.88e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" 0.0 3.3 12.4 0.3 18.7 0.0 2.7 0.0 27.0 0.0 0.0 0.8 0.4 0.1 0.0 0.3 0.2 0.1 0.1 22.6 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.2 0.0 29.6 0.7 0.1 28.8 0.0 0.0 2.8 0.7 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 12.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.4 0.1 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 18.7 0.0 27.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 2.9 0.0 0.1 0.2 0.0 0.0 0.0 1.8 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.8 3.2 0.0 0.0 0.3 0.0 0.0 0.0 3.6 1.0 0.0 0.0 0.0 3.0 1.0 0.0 0.1 0.0 0.0 4.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.1 CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;salivary gland: 17.5" "Group enriched" "Detected in many" 28 "Excitatory neurons: 802.9;Inhibitory neurons: 624.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 17.2;SH-SY5Y: 53.5;U-266/70: 21.7;U-266/84: 16.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024106, HPA048036" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA024106: AB_1854211, HPA048036: AB_2680238" "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "unprognostic (1.05e-1)" "unprognostic (4.11e-3)" "unprognostic (3.48e-3)" "unprognostic (5.81e-2)" "unprognostic (2.30e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (6.44e-2)" "unprognostic (5.34e-4)" "unprognostic (3.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" 0.3 0.4 4.6 0.8 7.3 0.2 0.8 0.0 11.8 0.4 0.0 7.0 1.4 1.9 0.4 7.5 0.8 0.7 0.4 7.5 0.0 1.1 0.4 1.1 0.1 0.0 0.0 4.8 10.6 0.5 0.5 0.8 0.0 1.1 2.8 1.7 17.5 3.0 0.0 1.3 1.5 4.1 0.0 0.7 5.0 2.5 4.1 0.1 2.0 0.1 0.1 7.0 0.4 2.9 0.0 0.1 0.4 0.4 0.0 0.0 0.9 0.6 0.1 0.3 0.1 0.0 0.0 0.0 2.1 0.0 0.0 5.8 0.6 3.8 2.7 0.0 3.7 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 1.1 9.1 0.9 1.4 0.0 0.0 4.6 4.6 9.1 0.0 1.1 17.2 0.7 0.8 0.1 53.5 0.0 0.1 0.1 4.0 1.8 0.0 0.3 2.3 0.8 0.1 0.5 21.7 16.3 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 7.3 0.0 11.8 7.5 0.0 0.0 0.0 0.0 0.0 4.1 2.9 6.1 0.0 3.7 6.2 0.0 0.0 2.1 0.0 0.6 19.0 4.6 3.2 1.2 0.0 0.8 0.0 0.0 3.2 0.3 11.0 1.9 0.4 19.6 0.1 0.1 3.0 3.5 4.6 802.9 17.3 0.7 3.9 11.7 0.2 1.3 7.5 4.2 0.3 0.5 0.0 624.0 6.0 0.0 0.0 0.0 3.9 0.0 0.2 7.2 22.5 0.0 0.3 0.0 8.5 11.2 2.6 25.3 0.4 0.2 2.5 2.2 1.4 1.6 0.6 0.0 0.2 1.1 12.9 3.0 0.2 0.0 0.5 0.1 0.8 15.5 0.2 CHRM4 ENSG00000180720 "Cholinergic receptor muscarinic 4" P08173 11 46385098-46386608 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 18.5;intestine: 6.8;lymphoid tissue: 15.9;testis: 5.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in many" 6 "basal ganglia: 18.5;cerebral cortex: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 3.4;SCLC-21H: 10.0;U-2 OS: 2.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 16.8" "CAB022444, HPA072083" Enhanced Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "CAB022444: , HPA072083: " "unprognostic (7.11e-2)" "unprognostic (3.79e-1)" "unprognostic (5.31e-2)" "unprognostic (7.38e-2)" "unprognostic (8.63e-3)" "unprognostic (1.38e-1)" "unprognostic (6.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (2.96e-3)" "unprognostic (4.08e-3)" "unprognostic (5.02e-2)" "unprognostic (3.83e-2)" "unprognostic (3.64e-1)" "unprognostic (1.71e-1)" "unprognostic (3.56e-1)" "unprognostic (5.08e-2)" 0.1 0.5 1.6 0.2 18.5 1.7 0.1 0.0 4.6 0.1 0.0 1.5 3.2 0.1 0.0 0.0 0.1 0.0 0.1 1.8 0.1 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.2 0.2 1.2 0.0 0.0 0.0 0.1 2.4 0.1 0.0 0.0 2.0 6.8 0.1 0.0 15.9 0.6 5.0 1.7 2.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.2 0.0 0.1 0.0 2.1 0.0 0.1 0.1 0.1 1.0 0.1 0.2 0.2 0.0 1.8 0.1 1.3 0.1 0.0 1.6 0.2 0.4 0.1 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.1 0.0 0.7 0.2 0.1 0.4 0.1 0.1 0.0 3.4 0.0 0.0 0.1 10.0 0.2 0.2 0.0 0.1 0.2 0.1 1.7 0.0 0.3 2.8 0.0 0.0 0.5 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 18.5 0.0 4.6 1.8 0.1 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 72.1;prostate: 29.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.5;Inhibitory neurons: 14.8;Prostatic glandular cells: 2.4;Theca cells: 3.4" "Cancer enriched" "Detected in single" 421 "prostate cancer: 30.2" "Region enhanced" "Detected in many" "thalamus: 72.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (3.19e-1)" "unprognostic (6.19e-2)" "unprognostic (6.29e-3)" "unprognostic (1.19e-2)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (7.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" 0.0 0.5 15.8 0.2 5.5 0.9 1.4 38.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.0 0.0 0.0 0.2 0.1 15.7 21.5 0.0 0.2 0.0 0.3 0.0 3.5 29.0 0.0 3.7 0.0 0.0 0.1 0.2 0.2 0.0 2.3 0.1 0.0 0.0 72.1 2.9 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 15.8 5.5 38.1 2.9 0.7 8.0 15.7 21.5 3.5 2.3 72.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 CHRNE ACHRE ENSG00000108556 "Cholinergic receptor nicotinic epsilon subunit" Q04844 17 4897771-4934438 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 55.3;pituitary gland: 27.6" "Cell type enriched" "Detected in many" 5 "Late spermatids: 161.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 9 "HEL: 5.0;HMC-1: 11.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "basal ganglia: 6.3" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.00e-3)" "unprognostic (1.56e-1)" "unprognostic (3.94e-2)" "unprognostic (4.35e-3)" "unprognostic (6.55e-2)" "unprognostic (2.27e-3)" "unprognostic (7.80e-4)" "unprognostic (7.75e-2)" "unprognostic (3.24e-1)" "unprognostic (1.34e-1)" "unprognostic (3.69e-2)" "unprognostic (6.58e-2)" "unprognostic (8.42e-4)" "unprognostic (1.39e-3)" "unprognostic (1.26e-1)" "unprognostic (5.83e-2)" "unprognostic (5.70e-2)" 0.7 0.4 0.1 0.4 0.1 0.7 0.7 0.6 0.4 0.7 0.0 0.3 0.3 0.4 1.3 0.4 0.6 1.0 55.3 0.2 0.1 1.0 3.5 0.8 0.5 0.3 0.0 0.8 1.7 0.2 27.6 0.6 0.1 0.6 0.0 5.1 0.8 0.2 1.8 2.2 0.8 0.2 0.0 1.8 0.5 0.7 0.1 0.1 0.4 2.1 0.2 0.3 0.5 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 5.0 0.0 0.8 0.4 0.0 11.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 1.3 2.5 0.4 0.0 0.0 0.1 0.8 0.2 0.4 0.1 0.7 1.1 0.8 0.6 0.1 0.0 0.7 0.1 0.1 0.6 0.4 0.2 0.1 0.3 0.0 0.1 0.0 0.1 0.2 4.9 0.0 0.0 0.3 4.2 1.7 1.4 0.8 1.2 5.0 1.6 2.0 6.5 1.5 0.6 1.8 4.2 0.6 10.2 0.0 1.9 0.3 27.8 0.6 1.1 3.3 0.0 0.0 0.5 0.9 7.3 2.3 1.1 0.8 8.2 1.4 2.9 7.4 3.4 3.3 0.4 0.1 2.0 1.3 13.0 161.5 0.9 9.9 0.0 2.8 5.3 1.1 8.2 0.5 0.7 0.7 0.0 0.4 3.5 1.1 0.0 2.9 0.6 10.0 0.0 0.9 1.1 5.6 8.4 0.2 1.1 11.1 3.5 6.2 0.2 0.7 CHST2 C6ST ENSG00000175040 "Carbohydrate sulfotransferase 2" Q9Y4C5 3 143119771-143124014 "Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.4" "Cell type enhanced" "Detected in many" "Muller glia cells: 114.4;NK-cells: 233.8;Plasma cells: 79.3;Sertoli cells: 92.1;Theca cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.3;NK-cell: 4.9;non-classical monocyte: 11.4" "Group enriched" "Detected in many" 5 "monocytes: 11.4;NK-cells: 4.9" "Cell line enhanced" "Detected in many" "ASC diff: 57.7;ASC TERT1: 58.8;HEL: 48.2;HHSteC: 118.4;HMC-1: 55.4;HSkMC: 62.3;U-266/70: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013620 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA013620: AB_2668861" "unprognostic (1.55e-2)" "unprognostic (2.20e-1)" "unprognostic (7.64e-3)" "unprognostic (2.75e-1)" "unprognostic (8.97e-3)" "unprognostic (2.83e-1)" "unprognostic (2.70e-2)" "unprognostic (2.06e-1)" "unprognostic (2.76e-1)" "unprognostic (4.11e-2)" "unprognostic (8.96e-3)" "unprognostic (9.15e-2)" "unprognostic (1.31e-2)" "unprognostic (7.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.58e-3)" "unprognostic (1.34e-1)" 7.7 2.7 17.8 8.1 13.7 16.8 6.3 16.7 14.6 5.7 6.0 3.0 2.1 8.4 1.4 1.1 2.1 1.7 5.6 9.7 13.4 8.4 1.3 7.5 7.7 31.0 18.4 4.9 1.3 0.9 6.9 10.3 28.1 7.4 1.1 11.0 2.7 9.9 1.6 4.4 7.5 3.7 21.4 18.2 3.4 1.7 28.7 14.5 6.7 0.8 5.4 7.1 7.6 48.4 0.0 0.3 3.1 2.6 57.7 58.8 0.2 3.3 9.5 2.3 2.1 0.0 0.0 0.6 2.0 2.3 3.1 0.1 2.3 8.2 1.2 0.8 1.5 48.2 0.1 0.0 118.4 1.2 55.4 62.3 9.7 3.1 10.1 3.6 3.6 7.2 5.5 2.9 15.4 0.0 9.1 12.2 16.5 0.0 8.0 0.5 1.0 0.1 1.7 2.2 3.7 0.0 0.7 0.0 5.6 2.9 0.0 1.9 12.3 7.0 4.1 9.5 13.9 52.4 0.8 3.3 13.8 9.3 37.4 0.7 0.5 0.7 0.3 4.3 0.0 1.1 0.1 0.2 1.6 0.8 0.6 0.5 0.3 4.9 11.4 0.1 0.5 0.9 17.8 13.7 16.7 14.6 9.7 13.4 31.0 18.4 28.1 21.4 28.7 48.4 11.3 0.0 0.0 3.6 17.7 2.4 7.3 2.5 0.0 25.0 2.8 2.7 1.4 0.0 1.8 3.7 2.1 0.6 41.9 0.0 0.0 0.4 0.2 5.7 29.8 9.4 0.0 39.1 6.8 0.2 0.6 14.4 2.0 6.5 11.4 12.5 3.6 0.4 2.8 1.7 8.1 0.0 0.0 10.3 32.2 1.3 12.8 20.2 17.8 1.0 13.6 114.4 233.8 2.5 6.1 5.9 0.0 2.2 79.3 13.1 0.0 0.0 0.1 23.8 92.1 0.8 20.2 0.0 2.2 0.1 0.6 1.0 9.8 58.1 1.3 14.8 CHST9 "GALNAC-4-ST2, GALNAC4ST-2" ENSG00000154080 "Carbohydrate sulfotransferase 9" Q7L1S5 18 26906481-27185308 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 13.8" "Cell type enhanced" "Detected in many" "Club cells: 115.2;Muller glia cells: 69.2;Oligodendrocyte precursor cells: 167.4;Respiratory ciliated cells: 311.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.3;Hep G2: 13.8;RPTEC TERT1: 41.8;SCLC-21H: 9.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA011393 Uncertain "Intracellular and membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA011393: AB_1846733" "unprognostic (9.24e-3)" "unprognostic (1.13e-2)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (4.53e-3)" "unprognostic (9.98e-3)" "unprognostic (9.21e-3)" "unprognostic (7.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.04e-2)" "unprognostic (3.54e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (3.93e-3)" 0.0 0.2 0.8 0.1 0.9 0.0 2.9 0.7 2.4 2.8 0.0 1.6 0.2 0.1 0.4 1.6 10.3 3.1 2.6 2.7 1.2 1.6 8.2 4.3 0.0 3.5 2.3 0.0 9.3 0.0 1.9 0.0 1.2 3.5 0.2 7.3 13.8 1.8 0.2 0.1 0.3 0.1 2.0 5.7 0.7 6.9 1.2 1.0 0.0 0.9 0.6 1.5 0.7 1.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 41.8 0.0 9.0 0.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.7 2.4 2.7 1.2 3.5 2.3 1.2 2.0 1.2 1.9 0.1 0.0 2.7 24.8 0.0 0.6 32.6 56.6 4.6 1.3 8.2 8.0 9.2 35.8 115.2 5.5 0.0 0.4 0.1 0.0 11.7 13.0 7.1 49.9 0.7 0.3 3.5 0.0 10.1 0.6 0.1 4.2 0.0 1.8 5.1 0.1 0.0 10.7 0.3 0.0 29.3 0.1 22.4 0.0 0.0 4.4 0.6 0.5 7.2 1.0 0.0 69.2 0.0 167.4 1.0 1.3 0.0 0.4 0.0 8.9 0.0 0.3 311.6 3.2 0.0 3.2 3.7 0.9 1.3 4.7 0.0 0.3 0.4 0.0 0.0 40.3 CHSY3 "CHSY-2, CSS3" ENSG00000198108 "Chondroitin sulfate synthase 3" Q70JA7 5 129904465-130186634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 509.1;Inhibitory neurons: 349.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 2.0;basal ganglia: 2.6;cerebral cortex: 2.9;hippocampal formation: 2.5;white matter: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.1;ASC TERT1: 11.5;HSkMC: 7.6;TIME: 7.4;U-138 MG: 14.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044612 Uncertain "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA044612: AB_10795883" "unprognostic (3.43e-2)" "unprognostic (6.28e-3)" "unprognostic (1.76e-2)" "unprognostic (5.83e-2)" "unprognostic (5.88e-2)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (9.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.08e-6)" "unprognostic (5.22e-3)" "unprognostic (9.93e-2)" "unprognostic (4.61e-3)" "unprognostic (1.74e-2)" 6.0 0.5 2.0 1.0 2.6 0.0 2.8 0.0 2.9 4.5 0.0 0.7 0.5 1.5 0.1 0.6 1.1 2.8 1.3 2.5 0.2 0.2 1.7 1.8 0.5 0.0 0.4 0.3 0.3 0.4 0.3 2.2 0.0 0.5 0.5 1.0 0.5 0.6 1.0 1.3 0.5 2.0 0.2 0.7 0.5 0.7 0.4 0.2 1.2 0.5 0.4 1.7 1.9 1.1 0.0 0.1 1.2 0.0 13.1 11.5 1.0 3.0 0.1 0.4 0.4 0.0 0.1 0.0 0.3 4.6 0.0 0.0 0.0 0.1 0.0 0.0 1.6 1.9 5.6 0.5 1.2 0.0 0.0 7.6 0.0 0.1 1.2 0.6 3.2 0.0 0.0 1.9 5.2 0.0 0.0 0.0 0.7 0.0 1.2 0.4 5.7 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.3 1.1 0.2 0.5 7.4 14.2 3.0 0.2 2.0 0.0 0.0 0.0 0.3 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.6 0.0 2.9 2.5 0.2 0.0 0.4 0.0 0.2 0.4 1.1 2.0 9.6 1.1 20.2 0.0 0.5 0.0 0.0 1.2 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.9 0.5 14.8 2.4 0.0 0.0 509.1 0.0 0.1 2.9 0.0 0.3 0.0 4.1 3.6 1.8 1.9 0.0 349.5 0.0 0.0 1.3 0.7 0.1 1.2 0.1 3.6 87.1 0.0 1.3 0.0 76.9 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.1 6.6 0.9 6.3 1.6 0.7 0.3 0.3 0.4 0.2 0.6 0.0 0.1 CIBAR1 "FAM92A, FAM92A1, FLJ38979" ENSG00000188343 "CBY1 interacting BAR domain containing 1" A1XBS5 8 93698561-93731527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 110.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 13.3;Extravillous trophoblasts: 14.1;Fibroblasts: 8.4;Hofbauer cells: 6.4;Syncytiotrophoblasts: 3.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034760, HPA058942" Enhanced Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA034760: AB_10599947, HPA058942: AB_2732628" "unprognostic (2.65e-3)" "unprognostic (6.81e-2)" "unprognostic (2.48e-3)" "unprognostic (2.44e-1)" "unprognostic (1.62e-2)" "unprognostic (2.93e-1)" "unprognostic (3.56e-1)" "unprognostic (3.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (2.28e-3)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "unprognostic (6.85e-3)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (3.07e-2)" 14.3 23.9 17.5 5.6 18.8 3.5 10.9 18.6 25.0 16.5 22.9 14.2 3.2 16.0 26.2 5.0 13.1 14.1 25.3 17.8 16.2 20.2 18.5 9.9 5.7 13.4 14.5 18.0 21.1 21.5 20.8 10.1 13.3 12.1 5.9 14.1 5.7 11.6 10.3 6.6 7.7 15.0 12.9 5.7 9.8 110.2 17.1 5.0 14.5 11.1 3.1 14.6 9.3 17.4 37.8 20.0 52.9 54.6 55.8 78.9 14.0 34.2 49.8 45.2 43.5 3.5 8.6 3.2 42.7 50.7 52.0 26.6 54.0 32.5 41.0 1.2 29.5 21.5 20.8 18.7 64.1 1.0 5.5 50.4 14.3 44.3 36.0 64.9 49.0 18.1 13.4 1.7 35.8 14.2 23.8 4.1 22.2 0.8 1.1 2.3 39.7 0.8 35.3 8.7 15.3 18.7 24.4 0.5 41.6 23.7 8.2 11.8 27.2 44.2 17.4 46.3 28.0 2.6 2.7 1.2 38.8 3.0 15.8 0.1 1.7 0.0 0.1 1.2 0.2 0.4 0.4 0.1 2.9 0.0 0.1 0.3 0.0 1.3 0.1 0.3 0.8 0.5 17.5 18.8 18.6 25.0 17.8 16.2 13.4 14.5 13.3 12.9 17.1 17.4 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 14.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 CIDEA CIDE-A ENSG00000176194 "Cell death inducing DFFA like effector a" O60543 18 12254361-12277595 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "adipose tissue: 221.3;breast: 108.0" "Cell type enriched" "Detected in some" 78 "Breast glandular cells: 330.6" "Cancer enhanced" "Detected in some" "breast cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "hTEC/SVTERT24-B: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "unprognostic (2.96e-2)" "unprognostic (2.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (8.93e-3)" "unprognostic (3.20e-2)" "unprognostic (7.00e-2)" "unprognostic (3.72e-2)" "unprognostic (1.91e-3)" "unprognostic (3.17e-2)" "unprognostic (7.67e-3)" "unprognostic (1.96e-1)" 221.3 3.7 2.3 0.2 3.2 0.0 108.0 2.8 5.2 3.5 1.7 1.5 0.0 0.0 0.0 4.8 0.0 1.2 1.9 2.7 1.8 0.2 0.2 0.0 0.3 2.4 2.2 0.0 0.9 0.0 0.0 0.0 2.7 0.1 0.9 0.1 4.3 0.0 1.0 9.3 2.1 0.2 2.2 0.0 1.0 0.1 2.0 0.2 0.5 4.6 0.2 1.1 5.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.2 2.8 5.2 2.7 1.8 2.4 2.2 2.7 2.2 2.0 3.0 1.9 0.0 0.0 0.7 0.5 0.1 0.1 0.3 0.0 0.2 330.6 3.8 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 1.0 0.0 0.2 0.3 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.2 0.6 0.6 1.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.4 0.3 0.7 1.0 0.0 0.3 0.5 0.0 0.8 CIDEC "CIDE-3, FLJ20871, Fsp27" ENSG00000187288 "Cell death inducing DFFA like effector c" Q96AQ7 3 9866711-9880255 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 740.3;breast: 492.9" "Cell type enriched" "Detected in some" 7 "Proximal enterocytes: 219.4" "Group enriched" "Detected in many" 5 "breast cancer: 4.5;colorectal cancer: 1.4;liver cancer: 2.4;pancreatic cancer: 4.6;stomach cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC diff: 1683.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018837, HPA020553" Uncertain NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "HPA018837: AB_1846767, HPA020553: AB_1846769" "unprognostic (1.83e-2)" "unprognostic (3.08e-2)" "unprognostic (2.32e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-1)" "unprognostic (7.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-5)" "unprognostic (9.03e-2)" "unprognostic (1.81e-1)" "unprognostic (5.48e-3)" "unprognostic (8.14e-2)" "unprognostic (5.37e-5)" "unprognostic (9.47e-3)" "unprognostic (2.02e-1)" "unprognostic (7.46e-3)" "unprognostic (2.94e-2)" 740.3 5.6 0.1 1.1 0.2 0.0 492.9 0.0 0.4 1.2 0.0 15.9 68.9 4.6 0.3 0.7 2.2 5.0 9.5 0.1 0.1 2.1 10.0 0.2 1.2 0.1 0.2 0.4 7.4 0.1 0.2 0.0 0.2 2.3 3.9 0.0 16.2 3.7 6.1 18.1 89.8 1.6 0.1 0.2 7.4 0.9 0.2 1.5 3.9 11.6 0.0 13.3 4.8 0.2 0.0 0.2 0.0 0.0 1683.2 376.0 1.2 0.1 0.0 0.0 0.0 7.5 9.1 0.0 0.2 0.6 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 19.1 2.8 0.0 0.0 228.9 0.4 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.3 0.0 0.6 1.6 0.0 0.0 1.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 2.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 2.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 30.0 1.9 0.0 0.5 0.2 0.1 0.1 3.5 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.1 8.4 0.0 0.0 0.4 1.0 2.5 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 14.5 0.4 0.0 0.4 219.4 1.1 0.0 0.0 0.0 0.5 0.6 0.6 0.4 0.0 0.0 0.0 0.2 0.1 3.8 0.3 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CIP2A KIAA1524 ENSG00000163507 "Cellular inhibitor of PP2A" Q8TCG1 3 108549864-108589644 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.5;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 8.0;Exocrine glandular cells: 7.3;Extravillous trophoblasts: 12.9;Granulosa cells: 25.3;Hofbauer cells: 8.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039570 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA039570: AB_10796329" "unprognostic (2.02e-1)" "unprognostic (1.54e-2)" "unprognostic (2.31e-3)" "prognostic unfavorable (6.24e-5)" "unprognostic (3.10e-2)" "unprognostic (1.07e-2)" "unprognostic (1.91e-7)" "unprognostic (2.80e-3)" "unprognostic (2.53e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.18e-4)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (9.11e-3)" "unprognostic (3.73e-1)" "unprognostic (2.11e-1)" "unprognostic (1.25e-1)" 1.1 1.1 0.3 3.4 0.6 7.5 1.4 0.9 0.8 0.9 0.1 1.9 1.2 1.8 0.6 1.7 0.9 1.2 0.7 0.6 0.5 1.0 0.7 1.4 6.7 0.2 0.9 1.9 0.4 0.6 0.7 2.1 0.2 1.8 2.7 2.6 0.6 0.8 0.6 1.2 1.7 1.5 0.0 2.3 1.2 5.7 0.1 6.9 1.2 0.7 5.2 2.0 0.9 0.4 42.2 12.2 33.9 21.8 1.4 3.2 13.8 31.1 14.7 36.2 41.9 15.0 18.5 27.6 10.4 11.4 27.7 20.9 11.7 11.0 65.8 8.8 11.3 33.9 17.4 11.3 0.5 21.8 23.2 1.4 2.3 28.4 11.5 5.9 16.3 12.7 21.1 44.5 36.1 8.7 26.7 19.2 35.0 15.8 20.8 30.1 31.2 15.3 11.0 11.5 16.4 21.6 22.9 9.0 12.7 19.7 15.3 15.6 12.2 37.0 41.7 11.3 38.3 10.2 12.1 46.1 16.4 23.2 38.6 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.6 0.9 0.8 0.6 0.5 0.2 0.9 0.2 0.0 0.1 0.4 1.2 9.6 1.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 1.9 1.3 0.0 0.0 2.5 3.7 0.0 8.0 1.8 0.0 1.9 2.8 0.0 2.5 2.8 2.6 0.0 0.0 0.0 7.3 12.9 3.0 0.0 2.7 3.8 25.3 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.4 0.0 0.0 2.4 1.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.4 1.7 5.4 0.0 0.0 CIT "CITK, CRIK, KIAA0949, STK21" ENSG00000122966 "Citron rho-interacting serine/threonine kinase" O14578 12 119685791-119877320 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 72.8;Excitatory neurons: 147.0;Inhibitory neurons: 139.8;Oligodendrocyte precursor cells: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019082, HPA048812, HPA075506" Uncertain Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA019082: AB_1846803, HPA048812: AB_2680528, HPA075506: AB_2686752" "unprognostic (5.64e-2)" "unprognostic (5.00e-2)" "unprognostic (8.16e-2)" "unprognostic (5.12e-3)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (3.61e-6)" "unprognostic (6.02e-2)" "unprognostic (7.78e-2)" "unprognostic (4.42e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-2)" "unprognostic (2.55e-3)" "unprognostic (8.56e-2)" "unprognostic (1.50e-1)" "unprognostic (1.70e-1)" "unprognostic (3.30e-1)" 0.7 2.2 13.5 1.6 26.2 6.3 0.6 0.0 19.9 0.9 0.0 2.1 1.2 0.4 0.0 2.5 0.5 0.5 0.6 15.2 5.4 2.5 0.3 1.8 1.5 0.2 5.0 0.3 0.2 0.1 1.6 1.4 0.4 0.5 2.5 3.4 0.8 0.2 0.5 1.6 1.9 0.9 0.9 3.0 2.2 4.8 14.2 6.8 0.6 0.3 2.3 0.5 1.3 6.6 26.2 20.6 21.7 15.3 2.4 6.3 10.4 22.0 19.1 21.8 16.6 14.5 10.3 18.4 10.0 14.2 9.3 14.6 14.4 9.5 32.1 13.6 7.5 25.7 13.2 7.1 0.3 12.7 20.6 0.9 1.2 23.7 14.8 7.3 15.5 19.9 14.5 15.2 19.5 12.2 22.4 14.0 10.4 8.7 12.5 19.3 39.8 6.3 5.0 11.1 15.5 8.4 31.9 6.5 16.0 9.6 23.2 10.6 11.5 21.9 21.4 17.2 22.7 9.9 12.6 14.2 16.8 12.5 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.5 26.2 0.0 19.9 15.2 5.4 0.2 5.0 0.4 0.9 14.2 6.6 4.1 6.4 13.0 8.5 1.2 3.3 0.7 1.0 0.6 8.2 1.8 1.5 1.8 0.0 5.6 9.2 87.6 3.5 0.6 1.1 0.0 0.2 72.8 2.4 2.1 2.7 1.8 12.8 147.0 0.8 4.8 2.2 3.1 3.6 1.3 10.5 1.1 0.7 3.6 0.0 139.8 4.4 6.1 3.7 0.8 44.1 1.2 2.0 3.6 7.5 0.0 15.4 1.0 82.4 18.7 0.2 0.1 1.2 4.1 0.4 0.8 7.5 1.7 15.2 0.0 0.6 3.3 33.2 4.2 7.7 1.3 1.0 2.2 4.3 4.4 1.0 CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 67.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 122.9;Granulosa cells: 88.6;Spermatocytes: 151.7;Spermatogonia: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA008410, HPA027821" Enhanced Enhanced "Microtubules,Mitotic spindle,Centrosome" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Centrosome "HPA008410: AB_1846832, HPA027821: AB_10602208" "unprognostic (1.85e-1)" "unprognostic (2.09e-3)" "unprognostic (2.44e-2)" "unprognostic (4.07e-3)" "unprognostic (1.39e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.30e-2)" "unprognostic (6.60e-3)" "prognostic unfavorable (1.90e-5)" "unprognostic (2.01e-2)" "unprognostic (5.20e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" 6.0 6.4 3.7 10.0 3.8 67.8 5.7 10.8 5.3 3.2 1.3 8.9 12.1 5.1 4.4 10.4 3.5 4.1 6.0 3.2 4.1 5.1 4.0 5.3 19.4 4.8 3.8 3.2 1.5 4.3 4.5 10.6 5.2 5.6 9.5 7.7 4.6 4.2 2.9 13.9 9.5 8.5 3.3 9.4 5.4 32.5 3.7 33.7 6.3 3.4 20.2 7.2 5.0 3.1 77.6 40.0 155.7 76.4 19.7 19.5 39.6 124.7 70.7 137.4 87.2 59.7 92.3 142.5 19.3 89.2 65.7 86.2 107.6 61.7 188.8 103.0 90.4 129.8 42.6 41.4 8.6 129.7 50.4 14.5 24.6 64.5 83.3 41.2 84.0 62.0 55.3 58.1 152.8 36.0 91.2 64.8 92.2 116.6 42.4 86.2 88.6 62.6 42.1 40.9 47.6 62.4 68.9 49.0 37.1 78.7 54.4 61.7 56.7 38.7 60.9 62.0 124.1 33.4 56.3 173.9 27.3 67.3 105.7 86.0 14.1 22.0 10.3 21.0 9.3 25.3 15.7 12.8 15.8 33.0 12.0 10.4 4.3 5.8 28.7 32.8 33.6 10.0 3.7 3.8 10.8 5.3 3.2 4.1 4.8 3.8 5.2 3.3 3.7 3.1 6.7 6.4 2.8 5.2 41.2 15.0 4.5 32.8 22.2 13.1 11.2 13.2 10.8 2.8 11.4 1.8 6.2 44.3 30.9 7.5 9.8 4.9 41.3 19.4 16.1 12.7 7.2 122.9 10.3 6.0 38.1 12.1 10.7 10.1 16.5 88.6 17.5 5.5 31.8 1.7 12.4 13.6 20.3 24.5 13.7 51.7 7.5 18.5 0.0 6.5 22.9 12.9 5.2 3.5 2.0 2.6 4.6 17.0 30.8 3.7 6.3 9.4 3.7 6.6 6.6 7.6 12.1 151.7 87.5 41.3 15.3 10.0 27.1 29.6 17.9 3.9 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 13.1;lymphoid tissue: 12.1;testis: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Granulosa cells: 12.5;Spermatocytes: 33.0;Spermatogonia: 35.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 0.4 0.1 0.2 2.6 0.2 13.1 0.4 0.4 0.3 0.4 0.0 1.6 1.5 0.3 0.1 2.3 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.2 0.2 0.3 0.0 0.0 1.5 1.1 1.1 0.0 0.9 1.0 4.5 0.2 12.1 0.2 0.0 5.2 0.8 0.6 0.2 47.9 9.6 35.4 16.2 2.0 3.3 7.2 38.5 32.2 37.9 36.1 8.7 13.3 32.0 15.5 15.1 48.3 18.0 20.4 19.6 64.1 44.8 8.9 53.6 12.7 7.7 0.1 25.2 30.9 0.9 1.9 47.4 27.2 10.1 17.5 22.8 14.3 44.9 31.2 6.9 31.0 10.6 15.4 20.0 29.5 22.3 37.0 8.4 6.9 18.7 19.7 12.7 15.2 12.8 13.3 13.2 12.4 11.8 12.9 42.7 33.7 34.5 28.5 9.9 20.1 26.6 18.5 18.1 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.2 0.6 0.0 1.2 3.3 2.1 2.7 0.6 0.0 0.5 0.8 0.5 1.5 0.4 0.0 0.0 11.1 1.3 1.3 0.0 0.4 2.4 1.1 1.6 1.1 0.0 25.2 0.3 0.4 10.6 2.0 1.5 2.1 0.0 12.5 2.9 0.1 6.6 0.0 0.2 3.1 2.0 1.9 1.4 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 5.6 1.1 0.1 0.1 0.4 0.0 0.0 0.4 2.8 33.0 35.7 9.5 1.7 1.0 2.5 0.7 3.8 1.1 CKAP5 "ch-TOG, KIAA0097, TOG, TOGp" ENSG00000175216 "Cytoskeleton associated protein 5" Q14008 11 46743048-46846308 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 119.7;Spermatocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039377, HPA040375" Supported Approved "Nucleoli,Nucleoli rim,Plasma membrane,Centrosome" NA Yes 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centrosome" "Nucleoli, Nucleoli rim" "HPA039377: AB_10805477, HPA040375: AB_10794739" "unprognostic (8.00e-2)" "unprognostic (7.35e-2)" "unprognostic (2.35e-1)" "unprognostic (4.12e-2)" "unprognostic (1.91e-1)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (6.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-2)" "unprognostic (4.30e-3)" "unprognostic (3.77e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (4.69e-2)" 12.8 30.7 15.9 15.1 19.5 25.9 14.9 30.8 24.3 11.7 5.2 18.5 12.6 15.7 12.2 13.0 11.5 12.2 21.3 21.4 18.0 11.5 45.5 10.4 18.4 21.0 17.4 27.8 9.0 21.2 12.5 17.3 22.9 15.9 17.2 57.0 9.1 13.2 37.8 13.7 12.3 19.3 17.5 11.9 16.1 33.0 20.2 36.4 9.6 28.8 18.5 13.5 10.8 24.6 104.7 95.8 212.6 90.8 48.7 73.0 48.3 117.1 69.4 107.8 114.6 76.8 33.3 104.5 41.0 76.0 117.0 116.2 144.0 62.7 134.3 102.0 107.6 176.6 80.2 78.4 35.0 139.6 76.7 37.0 34.0 60.3 125.6 56.1 79.3 97.9 129.5 103.8 89.2 71.2 127.9 39.2 114.7 78.8 73.0 131.2 210.0 98.3 34.7 63.3 96.8 83.9 149.8 56.9 57.3 88.9 103.9 39.1 64.0 106.2 92.9 180.8 176.2 59.2 137.3 158.6 66.5 64.9 105.9 4.6 4.2 4.6 6.1 6.2 5.9 6.5 4.5 6.9 6.1 6.2 5.4 5.8 0.7 8.6 6.2 3.9 5.6 3.1 15.9 19.5 30.8 24.3 21.4 18.0 21.0 17.4 22.9 17.5 20.2 24.6 13.4 25.6 23.6 32.3 17.4 8.5 11.0 17.9 16.5 19.3 11.6 12.3 65.2 12.8 18.8 9.2 37.5 19.4 11.2 13.3 9.8 12.2 119.7 19.7 21.0 16.5 12.1 32.6 61.9 7.8 15.0 27.8 29.0 18.8 37.9 55.5 11.7 8.1 18.7 13.5 63.1 16.9 16.2 17.6 5.6 50.7 19.6 19.6 7.2 30.9 16.5 16.2 16.5 32.6 51.7 13.7 15.2 29.0 26.4 14.2 9.1 9.3 30.7 25.6 19.7 18.0 21.4 107.4 59.3 24.3 11.6 11.5 16.1 83.3 19.8 9.7 CKMT2 SMTCK ENSG00000131730 "Creatine kinase, mitochondrial 2" P17540 5 81233320-81266398 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 49 "heart muscle: 1240.1;skeletal muscle: 1430.8;tongue: 2324.4" "Cell type enriched" "Detected in many" 20 "Cardiomyocytes: 814.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.1" "Cell line enhanced" "Detected in many" "BEWO: 3.5;T-47d: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051880 Enhanced NA NA 3000000 "Cluster 48: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA051880: AB_2681650" "unprognostic (3.64e-3)" "unprognostic (1.15e-1)" "unprognostic (2.82e-3)" "unprognostic (1.88e-2)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (3.57e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.75e-3)" 18.2 33.6 12.3 0.8 15.0 0.1 4.6 17.3 12.3 8.1 24.4 3.2 1.1 6.4 11.4 20.2 6.9 8.1 1240.1 11.2 15.0 14.7 1.0 2.5 1.3 16.3 16.8 10.2 7.7 15.7 4.5 0.7 14.9 13.1 0.7 1.6 26.3 13.1 1430.8 4.7 2.8 8.8 12.0 1.8 17.9 3.6 16.1 0.8 4.9 2324.4 0.4 4.1 4.1 17.7 0.3 0.7 0.8 1.3 1.9 0.4 3.5 0.1 0.0 0.0 0.0 2.4 0.2 1.4 0.4 0.0 1.0 0.0 0.0 0.0 0.0 1.5 2.4 0.1 1.0 3.2 2.6 0.6 0.2 0.8 0.0 0.0 0.0 0.3 0.0 2.1 0.3 0.5 0.0 2.2 1.2 0.2 1.0 0.0 0.7 0.6 1.0 0.1 0.0 0.0 1.4 1.0 1.2 0.3 1.4 1.5 6.3 0.3 0.7 0.4 1.2 0.7 0.2 0.2 0.1 1.3 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 12.3 15.0 17.3 12.3 11.2 15.0 16.3 16.8 14.9 12.0 16.1 17.7 1.8 0.0 0.5 40.1 0.0 0.1 0.4 0.0 1.2 0.9 0.9 0.8 814.1 7.2 0.6 12.9 0.0 0.1 0.0 0.1 37.2 1.7 25.1 13.6 3.5 9.8 0.0 0.0 11.4 0.6 0.4 16.2 6.6 27.8 0.0 0.8 0.0 0.0 0.1 0.0 18.1 0.3 0.0 0.0 0.0 2.2 7.2 0.3 3.6 23.4 0.0 1.4 0.0 4.5 9.1 0.4 0.0 15.1 0.0 0.3 0.3 0.6 0.7 1.0 0.0 11.6 15.0 1.0 0.4 0.1 0.1 0.3 0.8 23.7 2.5 0.2 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 117.5;skin 1: 88.7;vagina: 53.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 47.4;Basal respiratory cells: 57.5;Basal squamous epithelial cells: 39.9;Club cells: 37.1;Early spermatids: 30.2;Squamous epithelial cells: 167.1;Suprabasal keratinocytes: 54.8;Urothelial cells: 52.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 146.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "hTCEpi: 210.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 96000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: AB_2679977" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-3)" "unprognostic (6.99e-2)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (9.99e-3)" "unprognostic (1.97e-8)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" 0.8 0.1 0.2 0.1 0.6 0.0 4.6 0.4 0.5 22.8 0.1 0.6 0.2 0.0 0.5 117.5 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.7 0.4 2.4 0.7 0.0 13.2 0.2 0.2 88.7 0.8 0.0 0.4 0.0 0.1 0.6 0.3 1.0 0.0 0.0 26.0 21.2 53.1 1.0 0.0 0.0 0.0 0.0 0.6 3.0 38.9 1.7 2.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 0.0 33.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 210.8 1.0 10.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.9 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.4 0.5 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.7 0.0 47.4 13.1 57.5 39.9 0.0 7.7 2.8 0.4 0.0 37.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 5.3 4.1 0.0 3.1 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 2.5 2.1 0.3 0.0 8.0 0.0 0.0 0.0 0.6 0.2 0.0 167.1 54.8 0.1 0.5 0.0 0.1 52.9 CLCNKA hClC-Ka ENSG00000186510 "Chloride voltage-gated channel Ka" P51800 1 16018875-16034050 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 344.0" "Cell type enriched" "Detected in some" 4 "Late spermatids: 271.5" "Group enriched" "Detected in some" 7 "renal cancer: 4.4;thyroid cancer: 1.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-266/70: 7.4" HPA057717 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA057717: AB_2683509" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.37e-2)" "unprognostic (4.02e-1)" "unprognostic (2.76e-3)" "unprognostic (8.20e-2)" "unprognostic (6.16e-2)" "unprognostic (1.18e-2)" "unprognostic (6.92e-3)" "unprognostic (3.49e-2)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (8.13e-3)" "unprognostic (1.36e-1)" "unprognostic (9.13e-2)" "unprognostic (4.37e-3)" "unprognostic (1.28e-1)" 0.7 2.9 0.4 0.0 0.4 0.0 0.9 2.2 0.4 0.6 4.9 0.4 0.0 0.6 0.5 0.0 0.5 0.1 0.6 0.7 0.4 344.0 0.2 0.3 0.0 0.4 0.5 0.9 3.5 48.9 18.2 0.0 0.7 0.8 0.0 2.3 6.9 0.2 0.5 0.7 0.1 0.2 0.3 0.1 3.9 4.5 0.4 0.0 21.6 0.3 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 2.2 0.4 0.7 0.4 0.4 0.5 0.7 0.3 0.4 0.4 0.0 3.2 0.5 0.3 0.0 0.1 0.1 0.0 0.0 3.9 0.4 0.1 3.8 0.0 0.7 25.8 0.0 0.4 0.0 0.1 25.4 0.3 40.2 0.1 0.0 0.1 1.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 4.5 0.0 0.0 0.1 13.5 0.2 0.1 67.1 0.0 0.0 271.5 0.3 0.0 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.1 1.9 1.2 0.0 0.0 0.7 0.1 0.0 0.3 0.2 CLDN1 "ILVASC, SEMP1" ENSG00000163347 "Claudin 1" O95832 3 190305707-190322446 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" Ichthyosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 309.8;skin 1: 288.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 440.1;Basal prostatic cells: 291.1;Prostatic glandular cells: 501.6;Squamous epithelial cells: 298.2;Suprabasal keratinocytes: 836.1;Urothelial cells: 562.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "EFO-21: 658.6;HaCaT: 236.5;hTCEpi: 288.6;RPTEC TERT1: 414.9;RT4: 267.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 12 "spinal cord: 25.4" "CAB002602, HPA048319" Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "CAB002602: , HPA048319: AB_2680355" "unprognostic (5.89e-2)" "unprognostic (4.58e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (7.92e-3)" "unprognostic (2.43e-1)" "unprognostic (3.54e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (5.23e-4)" "unprognostic (3.06e-1)" "unprognostic (1.13e-1)" "unprognostic (4.43e-2)" "unprognostic (9.20e-2)" "unprognostic (1.09e-3)" "unprognostic (1.22e-1)" 40.8 47.9 1.5 1.2 1.1 0.2 22.7 0.8 1.3 17.7 20.7 1.7 1.1 64.2 31.9 40.9 56.6 15.5 2.5 1.5 1.2 10.5 309.8 9.1 0.5 1.2 2.8 6.3 34.3 0.4 2.4 5.3 1.7 13.6 1.6 0.9 34.0 46.0 1.1 288.2 0.7 126.6 0.7 1.5 1.0 4.3 1.1 9.4 36.2 4.9 44.2 40.4 35.9 1.0 34.0 29.7 0.2 0.1 0.0 0.1 0.0 2.5 52.7 1.1 2.1 17.7 69.1 0.0 658.6 0.3 58.5 236.5 1.5 77.7 6.2 0.9 1.4 0.1 9.3 41.5 49.6 0.4 0.2 0.5 288.6 6.0 87.0 2.4 0.6 0.0 0.1 0.1 0.1 6.5 0.1 0.1 1.5 2.3 5.5 0.0 0.6 0.2 414.9 267.0 0.2 0.0 31.0 5.7 18.4 3.5 53.5 0.5 12.9 0.6 9.9 0.2 1.4 0.7 0.6 1.2 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.8 1.3 1.5 1.2 1.2 2.8 1.7 0.7 1.1 1.0 0.4 12.8 34.7 0.0 0.5 440.1 291.1 217.3 84.2 0.0 35.6 2.0 1.0 170.1 143.2 31.3 0.0 2.4 0.6 0.6 0.0 203.3 0.1 44.4 10.0 7.0 1.8 0.0 0.7 56.3 0.3 29.2 2.0 100.0 1.3 0.4 1.4 188.2 1.0 0.0 1.6 0.3 54.9 3.8 66.5 1.7 15.5 8.5 32.0 0.0 5.7 0.0 0.0 24.6 0.0 139.9 0.0 35.3 0.0 501.6 0.1 4.1 144.6 0.0 0.0 0.3 11.2 0.3 0.8 298.2 836.1 33.8 2.6 5.0 1.0 562.9 CLDN10 "CPETRL3, OSP-L" ENSG00000134873 "Claudin 10" P78369 13 95433604-95579759 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 135.2;pancreas: 216.5;salivary gland: 91.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 182.4;Cholangiocytes: 328.8;Club cells: 251.6;Ductal cells: 394.1;Glandular and luminal cells: 220.2;Proximal tubular cells: 285.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 19.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 1.3;neutrophil: 4.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 4.1" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 14.9;NTERA-2: 12.7;RPTEC TERT1: 29.0;SuSa: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012969, HPA042348" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB012969: AB_2533386, HPA042348: AB_2677955" "unprognostic (6.45e-2)" "unprognostic (5.72e-2)" "unprognostic (3.35e-1)" "unprognostic (4.60e-2)" "unprognostic (4.73e-2)" "unprognostic (2.46e-3)" "unprognostic (6.91e-2)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "unprognostic (1.91e-3)" "unprognostic (2.59e-3)" "unprognostic (7.93e-2)" "prognostic favorable (7.46e-5)" "unprognostic (1.11e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.13e-4)" "unprognostic (4.75e-3)" 1.0 0.1 33.0 0.0 31.3 3.2 3.1 28.6 45.8 30.4 24.1 0.3 1.1 9.3 20.8 7.9 19.2 25.5 0.5 32.6 30.5 135.2 3.7 2.1 0.0 27.9 30.2 0.9 216.5 0.4 3.1 0.8 27.2 1.3 0.4 2.7 91.5 0.4 0.1 16.8 0.2 0.4 27.4 0.7 0.9 1.5 30.1 0.5 0.2 0.7 27.4 0.5 0.4 29.8 0.0 0.0 0.9 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 2.7 0.0 4.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.3 1.9 0.0 0.0 2.9 0.0 0.1 0.0 0.5 14.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 12.7 0.2 0.0 0.0 0.1 0.0 29.0 0.0 0.2 0.1 0.0 0.0 0.0 73.3 0.7 1.8 0.6 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.0 33.0 31.3 28.6 45.8 32.6 30.5 27.9 30.2 27.2 27.4 30.1 29.8 0.6 0.0 0.0 93.4 1.0 0.3 5.5 182.4 0.0 0.3 22.6 5.0 0.8 328.8 251.6 99.3 0.0 15.0 0.4 0.0 135.0 394.1 3.4 83.2 28.5 4.2 0.0 0.0 0.6 82.5 7.9 1.4 0.0 220.2 0.0 0.1 1.1 0.4 1.9 0.0 1.6 0.0 77.3 0.3 0.3 2.5 0.0 2.8 69.4 4.7 1.6 78.7 0.0 33.7 0.4 103.1 0.0 0.4 0.1 22.1 0.0 285.9 43.3 3.8 6.6 0.2 16.8 12.2 19.9 1.5 0.6 23.1 2.2 0.5 0.0 5.0 CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.4;stomach 1: 15.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 418.8;Paneth cells: 449.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 7.7;Daudi: 6.4;RT4: 6.7;SK-BR-3: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" 6.2 1.1 0.3 2.3 0.4 0.1 5.7 0.2 0.3 2.4 2.3 16.4 4.1 1.0 1.9 3.3 1.4 1.2 0.7 0.3 0.3 4.5 10.4 4.7 0.3 0.5 0.4 1.6 4.0 2.1 0.9 1.5 0.4 1.3 6.8 0.1 6.8 1.3 0.5 13.5 10.1 0.3 0.4 1.8 15.6 0.5 0.5 0.1 4.9 0.3 0.3 5.0 2.7 0.6 0.1 2.6 0.0 0.1 0.7 0.1 7.7 1.9 1.5 2.0 3.1 1.5 4.2 6.4 0.0 0.1 0.7 2.5 0.0 0.0 0.2 1.3 0.0 0.0 0.7 0.1 3.5 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.3 0.0 0.2 1.9 0.3 1.3 0.0 0.0 0.0 0.9 6.7 0.3 0.9 2.6 6.8 0.1 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.9 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.4 0.2 0.3 0.3 0.3 0.5 0.4 0.4 0.4 0.5 0.6 13.0 9.6 3.1 0.3 1.1 0.1 6.6 4.2 2.2 0.1 6.8 3.4 0.7 30.0 6.9 1.8 0.0 19.1 2.8 418.8 7.9 26.9 0.0 6.0 2.5 3.4 7.7 0.0 0.0 10.7 14.9 3.3 59.7 6.7 4.5 0.8 8.2 10.6 16.8 0.0 0.0 49.9 26.4 2.4 1.4 0.0 0.3 4.6 3.6 1.9 1.4 1.1 0.0 0.0 0.0 28.1 449.9 0.4 0.1 3.3 99.1 4.7 10.3 1.1 6.6 1.5 3.2 0.0 0.0 3.9 0.6 9.4 1.3 0.3 55.2 12.2 CLDN3 "C7orf1, CPE-R2, CPETR2, HRVP1, RVP1" ENSG00000165215 "Claudin 3" O15551 7 73768997-73770270 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 263.1;thyroid gland: 116.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1839.9;Endometrial ciliated cells: 1221.7;Glandular and luminal cells: 1555.7;Intestinal goblet cells: 1471.3;Paneth cells: 2326.0;Proximal enterocytes: 3162.1;Undifferentiated cells: 1266.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 529.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 230.7;PC-3: 47.6;RPMI-8226: 40.5;SCLC-21H: 58.0;T-47d: 105.4" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Region enhanced" "Detected in many" "midbrain: 9.7" HPA014361 Enhanced Supported "Cell Junctions" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA014361: AB_2668982" "unprognostic (1.84e-1)" "unprognostic (4.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.27e-2)" "unprognostic (2.61e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (8.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.28e-3)" "unprognostic (1.42e-1)" "prognostic favorable (3.39e-5)" "unprognostic (1.46e-2)" "unprognostic (1.87e-1)" "unprognostic (5.18e-2)" "unprognostic (6.72e-2)" 0.7 0.2 0.2 7.8 0.3 0.2 26.7 4.2 0.3 12.3 37.6 263.1 54.4 7.5 1.4 1.3 29.6 2.2 0.1 1.1 1.2 46.5 40.4 10.7 0.2 1.3 1.9 0.5 96.6 1.5 27.7 1.0 0.6 58.3 17.5 0.4 72.9 8.3 0.1 9.6 169.5 0.8 0.5 0.2 1.4 0.7 0.9 1.0 116.3 0.0 1.2 1.5 0.2 0.2 2.5 3.6 0.0 0.4 0.0 0.0 17.8 0.0 0.0 0.0 0.0 4.2 35.7 0.0 9.9 0.0 0.0 1.0 0.4 0.0 0.0 0.1 4.9 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 230.7 0.4 1.2 2.1 9.1 47.6 0.1 0.0 40.5 2.1 0.2 58.0 0.7 0.0 33.6 0.0 0.2 105.4 0.0 0.2 0.2 0.6 0.9 0.1 0.2 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 4.2 0.3 1.1 1.2 1.3 1.9 0.6 0.5 0.9 0.2 1.6 38.5 37.8 0.0 13.2 0.1 60.3 43.7 0.0 0.7 289.9 182.5 0.6 287.4 86.3 126.9 4.2 63.9 5.1 1839.9 9.8 297.5 0.0 1221.7 130.5 10.3 606.1 5.3 0.0 19.1 17.7 4.1 16.8 1555.7 28.0 1.5 0.4 40.5 5.1 0.0 0.0 1471.3 116.0 0.3 0.0 0.3 2.5 9.9 10.6 0.0 2.0 11.8 0.0 0.0 0.0 36.7 2326.0 0.0 4.4 433.2 3162.1 58.6 498.4 10.6 0.0 0.0 20.3 0.1 0.3 2.7 0.0 72.4 17.5 0.0 1266.0 607.3 CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 305.0;urinary bladder: 303.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 3149.1;Glandular and luminal cells: 2298.8;Paneth cells: 2081.0;Prostatic glandular cells: 2184.8;Urothelial cells: 8033.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 358.1;BEWO: 395.0;CAPAN-2: 761.4;MCF7: 400.2;OE19: 402.0;PC-3: 495.0;RT4: 340.2;SK-BR-3: 636.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" 2.6 0.4 0.1 23.0 0.0 0.2 69.0 0.8 0.3 61.2 4.8 256.3 126.9 26.7 24.4 305.0 75.8 48.9 0.4 0.2 0.0 116.2 4.8 64.0 1.0 0.4 1.5 1.2 116.2 51.9 13.1 36.3 0.3 82.2 123.3 0.3 204.6 39.1 0.5 180.8 190.6 7.3 0.0 0.7 13.3 0.6 0.2 10.7 111.7 0.3 37.5 303.5 105.7 0.0 358.1 4.4 0.0 1.5 0.0 0.4 395.0 3.3 0.2 0.3 0.4 184.9 761.4 0.6 28.0 0.1 2.6 193.3 0.0 0.5 0.4 0.7 0.4 0.2 20.3 127.0 0.1 0.1 0.9 0.0 1.9 0.1 0.4 0.3 0.0 0.2 0.3 0.7 0.0 400.2 0.7 1.9 0.7 402.0 495.0 0.5 6.9 7.6 92.4 340.2 79.5 1.7 0.4 636.8 0.8 21.6 250.9 0.9 0.5 0.9 13.7 3.1 3.5 0.9 0.7 0.7 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.3 0.2 0.0 0.4 1.5 0.3 0.0 0.2 0.0 5.1 275.7 230.2 0.0 12.2 16.2 3149.1 641.6 31.3 0.4 1255.2 548.4 0.8 287.4 954.3 218.8 0.0 771.7 18.7 1985.0 13.7 1026.1 0.0 1201.7 231.0 41.3 675.5 0.0 0.2 447.1 739.7 27.0 94.8 2298.8 27.3 0.2 0.4 0.5 76.3 0.0 0.1 1266.9 905.3 0.6 8.6 0.0 2.5 29.3 14.2 0.0 15.6 0.8 0.0 0.0 0.0 950.2 2081.0 0.0 2.5 2184.8 1906.1 21.6 635.6 0.0 0.0 0.1 68.2 0.0 0.2 1068.1 54.0 956.1 40.7 0.1 965.1 8033.4 CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 341.3;intestine: 341.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1391.1;Pancreatic endocrine cells: 822.1;Paneth cells: 1276.4;Proximal enterocytes: 1390.9;Urothelial cells: 975.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 84.1;CACO-2: 90.2;CAPAN-2: 173.2;HaCaT: 364.9;MCF7: 129.8;OE19: 139.6;SK-BR-3: 150.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" 6.7 8.0 0.4 17.6 0.4 0.2 31.2 0.5 0.6 47.3 0.4 341.0 146.7 4.8 43.9 341.3 41.3 27.4 2.7 0.4 0.4 123.8 40.2 61.8 0.8 0.6 0.5 1.5 108.5 49.0 31.1 14.2 0.6 44.5 128.6 1.1 169.2 30.0 1.5 13.1 248.9 6.2 0.5 5.7 5.2 1.9 0.6 2.4 76.7 0.0 21.2 40.5 96.3 0.9 10.8 1.1 0.2 0.3 0.0 0.6 84.1 0.3 0.3 0.0 0.0 90.2 173.2 0.1 3.2 0.4 0.4 364.9 0.1 11.2 0.0 0.1 1.9 0.1 2.4 0.0 6.5 0.1 0.8 1.5 17.3 0.0 0.6 0.0 8.1 0.1 1.0 0.3 0.1 129.8 0.1 1.2 0.6 139.6 3.4 0.2 0.0 2.5 0.1 0.0 20.4 0.4 1.1 150.2 0.0 6.6 55.0 1.3 16.8 0.2 0.6 0.7 0.2 0.1 0.3 0.1 1.2 0.0 0.3 0.0 0.3 0.0 0.5 0.8 1.3 0.1 0.3 0.8 0.4 0.9 0.9 1.7 0.0 0.7 0.0 0.0 0.3 0.5 0.4 0.4 0.5 0.6 0.4 0.4 0.6 0.5 0.6 0.5 0.6 0.9 4.4 112.2 55.6 0.0 7.4 2.0 295.4 316.3 66.6 0.7 200.4 102.4 0.6 240.2 550.3 321.8 8.4 281.3 3.1 1391.1 39.2 787.5 0.1 210.1 26.6 9.0 326.8 4.0 0.0 790.0 342.7 5.2 15.3 225.5 5.7 0.1 3.6 41.2 33.7 0.0 0.0 741.7 362.2 4.1 6.4 0.2 1.2 11.0 24.9 1.9 11.0 1.6 0.0 0.0 0.0 822.1 1276.4 0.0 0.5 406.5 1390.9 78.6 498.5 6.7 0.0 0.2 38.6 0.4 3.5 366.1 2.6 588.9 10.2 1.0 691.9 975.8 CLDN8 ENSG00000156284 "Claudin 8" P56748 21 30214006-30216097 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 68.9;intestine: 50.8;kidney: 69.3;salivary gland: 40.1" "Group enriched" "Detected in some" 5 "Collecting duct cells: 224.3;Distal enterocytes: 110.2" "Cancer enhanced" "Detected in many" "prostate cancer: 31.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "HaCaT: 33.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA060605 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA060605: AB_2684331" "unprognostic (3.74e-2)" "unprognostic (3.12e-2)" "unprognostic (1.33e-1)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (1.62e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 68.9 0.0 0.0 1.7 0.0 27.2 0.0 0.1 9.3 3.9 1.1 0.0 0.0 0.0 0.0 69.3 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.5 0.0 7.5 50.8 0.0 40.1 13.9 0.0 8.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 21.9 0.0 0.3 0.4 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 10.8 2.7 0.0 0.0 29.9 11.6 0.0 0.0 10.5 224.3 0.0 0.0 0.1 110.2 11.7 0.1 0.0 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.4 0.0 0.3 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 15.9 0.6 0.4 20.3 0.0 0.0 0.0 0.3 0.0 0.0 4.6 8.4 0.0 0.4 0.0 18.0 23.1 CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 363.0;HMC-1: 637.3;NB-4: 901.1;THP-1: 694.7;U-937: 358.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" 17.5 17.5 5.0 7.0 5.6 132.6 14.1 7.9 9.1 44.4 2.9 12.0 4.8 31.9 1.6 8.4 37.5 6.2 16.3 4.4 7.2 21.1 12.1 15.0 2.7 10.2 7.9 31.5 7.5 2.4 22.3 5.5 8.1 22.5 1.9 0.7 6.9 4.8 4.4 16.8 9.7 8.1 7.2 14.0 8.0 9.1 6.2 2.6 12.8 1.0 0.8 19.2 28.2 6.0 2.6 3.5 0.0 2.9 33.7 45.3 79.2 139.3 37.9 15.6 15.7 0.1 0.0 0.4 1.7 70.2 0.8 1.6 0.4 0.2 10.7 0.6 22.9 363.0 0.1 0.0 21.3 0.2 637.3 33.7 0.2 1.9 2.3 0.1 17.9 16.1 4.1 2.2 29.0 2.6 3.1 901.1 1.6 0.3 4.6 30.7 0.2 0.2 0.8 0.4 0.0 3.8 4.2 0.0 58.1 0.0 0.9 694.7 100.3 1.1 41.6 0.7 0.7 2.1 2.2 0.5 47.3 358.7 44.2 1.4 24.3 0.4 0.9 11.5 0.1 0.6 0.3 0.2 17.7 0.4 2.0 4.5 1.6 5.7 5.6 4.8 0.2 8.2 5.0 5.6 7.9 9.1 4.4 7.2 10.2 7.9 8.1 7.2 6.2 6.0 12.4 3.2 5.4 10.4 3.9 32.0 32.2 2.9 27.3 20.5 30.8 31.9 3.4 8.6 4.0 29.5 10.4 8.6 5.0 1.7 119.3 11.0 6.5 17.0 70.7 16.9 26.5 36.4 9.0 3.1 72.4 107.2 4.1 14.1 5.7 18.9 51.4 6.3 49.4 21.9 8.3 4.5 10.2 21.5 73.3 19.9 70.8 29.6 78.2 9.4 11.2 70.4 14.4 8.0 12.9 3.1 1.7 67.4 0.9 21.4 0.5 13.7 5.0 20.7 65.7 20.2 59.2 17.2 21.7 26.3 45.9 18.3 5.8 56.7 3.5 17.8 CLEC1A "CLEC1, MGC34328" ENSG00000150048 "C-type lectin domain family 1 member A" Q8NC01 12 10069554-10111627 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 50.2;placenta: 49.0" "Cell type enhanced" "Detected in some" "Adipocytes: 51.4;Cytotrophoblasts: 51.5;Endothelial cells: 38.1;Extravillous trophoblasts: 61.7;Syncytiotrophoblasts: 52.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 21.3;HUVEC TERT2: 18.3;SuSa: 5.6;U-266/70: 4.9;U-266/84: 11.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (5.96e-2)" "unprognostic (2.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (7.15e-2)" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.94e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" 16.2 3.2 4.4 4.1 4.2 0.4 14.8 6.6 5.6 11.4 4.1 4.3 1.5 6.8 2.7 3.8 9.2 5.7 9.0 3.9 3.8 5.8 2.9 29.8 5.9 4.8 4.5 5.4 2.3 1.6 3.7 49.0 4.7 6.3 2.0 0.6 2.9 2.4 3.9 4.1 4.4 8.7 4.3 8.0 3.7 2.1 5.1 50.2 7.6 4.4 3.5 6.1 8.6 4.1 0.0 0.0 0.3 0.3 0.2 0.2 21.3 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 1.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.9 0.0 0.0 0.0 0.4 3.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.4 0.0 0.3 0.3 0.0 5.6 0.0 0.0 1.4 0.0 0.2 0.2 0.0 4.9 11.5 0.0 0.2 0.1 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 4.4 4.2 6.6 5.6 3.9 3.8 4.8 4.5 4.7 4.3 5.1 4.1 51.4 0.0 0.5 0.0 0.5 2.2 0.1 0.0 1.2 0.0 0.3 0.1 1.3 0.0 0.0 0.0 0.0 51.5 0.2 0.0 0.0 0.0 0.4 0.0 0.1 38.1 0.0 0.0 0.0 0.0 61.7 1.2 0.0 0.0 0.0 0.0 16.8 0.2 5.0 0.0 0.0 0.0 0.0 4.7 14.1 0.6 7.5 4.0 3.6 11.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.9 4.0 2.9 0.3 1.6 52.1 0.6 0.3 0.0 0.5 CLEC2A "INPE5792, KACL, PILAR, UNQ5792" ENSG00000188393 "C-type lectin domain family 2 member A" Q6UVW9 12 9898673-9932370 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 57.6" "Group enriched" "Detected in some" 11 "Basal keratinocytes: 18.7;Suprabasal keratinocytes: 37.1" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 22.0;U-937: 54.6" "HPA048530, HPA072407" Approved Uncertain "Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA048530: AB_2680429, HPA072407: AB_2686518" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" 0.0 0.0 0.1 0.0 0.2 0.0 3.5 2.1 0.3 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 57.6 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 54.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.1 0.3 0.2 0.3 0.5 0.3 0.5 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 37.1 0.0 0.1 0.0 0.0 0.1 CLEC4E "CLECSF9, mincle" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.7;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 31.9;Kupffer cells: 158.0;Macrophages: 115.2;monocytes: 109.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "classical monocyte: 128.8;neutrophil: 448.8" "Group enriched" "Detected in many" 17 "granulocytes: 448.8;monocytes: 128.8" "Group enriched" "Detected in some" 4 "NB-4: 4.3;RPTEC TERT1: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain Uncertain Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" 13.3 5.4 2.3 37.5 2.1 75.7 4.5 1.8 4.4 5.8 2.2 2.2 0.4 2.3 0.4 3.2 5.5 11.8 2.5 2.3 2.9 3.6 6.6 22.4 7.6 1.3 1.3 1.7 6.2 1.7 1.9 2.1 1.2 2.3 1.0 1.3 1.4 1.2 0.7 0.9 3.1 5.7 0.7 52.3 2.5 1.1 2.0 2.2 10.5 5.0 2.3 9.6 1.7 2.9 0.1 0.4 0.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.1 0.1 2.0 0.0 0.1 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.5 0.1 0.0 1.5 0.0 0.5 0.2 0.2 0.2 0.2 0.0 0.1 0.0 4.3 0.3 0.0 0.0 0.0 0.2 0.1 12.4 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.4 1.0 0.5 0.1 1.0 0.1 0.2 0.1 0.1 1.3 0.4 0.1 0.2 128.8 0.5 0.1 18.1 0.3 0.1 0.1 0.1 16.9 0.1 0.0 0.1 448.8 0.0 0.7 0.7 0.0 30.3 2.3 2.1 1.8 4.4 2.3 2.9 1.3 1.3 1.2 0.7 2.0 2.9 6.2 0.0 4.7 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 5.7 1.8 1.8 0.0 0.0 0.3 0.0 0.0 9.0 0.3 2.1 4.4 3.5 0.0 0.0 0.0 0.0 0.1 1.4 0.0 31.9 0.0 0.0 7.1 2.1 5.6 0.0 0.0 0.0 0.0 158.0 9.0 2.9 0.9 115.2 0.0 0.0 109.5 0.0 4.1 0.0 0.0 0.4 0.0 0.4 1.3 0.0 0.0 0.2 0.7 0.0 13.1 0.2 0.4 0.2 0.5 0.1 0.0 0.1 1.1 0.0 0.0 0.1 CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 41.3" "Group enriched" "Detected in some" 6 "Hofbauer cells: 18.0;Langerhans cells: 67.5;Macrophages: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Group enriched" "Detected in some" 23 "HL-60: 40.9;U-937: 157.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" 1.1 1.8 1.1 7.3 1.2 41.3 0.6 1.3 2.6 0.7 2.1 0.2 0.1 0.3 0.0 1.2 0.5 1.8 0.5 1.0 3.3 0.5 1.8 4.0 0.1 2.2 3.3 0.3 1.3 1.2 0.5 0.9 2.2 0.4 0.3 1.0 1.2 0.5 0.0 2.6 0.0 1.3 1.6 1.1 0.2 0.5 4.9 0.6 0.7 0.0 0.1 2.3 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.3 0.0 0.0 9.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 1.8 1.1 1.2 1.3 2.6 1.0 3.3 2.2 3.3 2.2 1.6 4.9 2.4 0.1 0.0 4.8 0.7 0.6 1.9 0.0 0.0 0.0 0.2 0.1 0.1 0.3 1.5 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.5 0.0 0.0 0.1 0.0 0.2 0.8 0.0 0.0 2.5 0.0 0.0 0.0 18.0 0.0 0.2 0.0 0.0 4.7 67.5 0.7 0.0 58.1 1.8 7.5 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.9 0.4 0.0 0.0 0.2 0.0 0.1 0.0 1.4 0.3 0.4 0.0 0.0 0.0 CLEC7A "CD369, CLECSF12, dectin-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 84.0;lung: 30.9;lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.2;Kupffer cells: 415.2;Langerhans cells: 291.5;Macrophages: 255.5;monocytes: 186.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 249.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Karpas-707: 192.2;U-266/84: 168.1" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" 9.9 5.9 2.2 44.5 2.0 84.0 4.5 2.6 3.7 3.5 3.3 7.5 5.6 3.2 3.7 9.7 5.8 11.1 5.7 1.9 3.3 3.5 11.0 30.9 14.4 5.0 2.7 2.4 2.9 2.0 2.7 7.3 4.0 3.3 7.3 1.7 7.3 3.2 1.3 3.8 8.6 8.7 3.6 34.2 4.6 1.5 3.8 10.0 2.6 2.0 11.9 9.1 4.8 6.1 0.3 0.4 0.1 0.2 0.0 0.0 1.1 0.0 0.5 0.2 0.1 0.1 0.4 0.1 0.1 0.0 1.1 0.6 0.0 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.9 0.7 0.1 0.8 0.1 0.0 0.2 0.1 0.2 0.0 192.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 4.3 0.0 5.2 0.3 0.2 0.3 0.6 0.0 1.4 0.4 0.1 0.3 0.1 0.2 0.2 0.2 11.4 168.1 0.1 0.3 1.0 0.2 1.4 122.9 2.2 0.3 137.2 0.5 0.3 0.3 0.2 60.6 0.3 0.3 0.2 249.6 0.4 148.1 1.0 0.4 40.4 2.2 2.0 2.6 3.7 1.9 3.3 5.0 2.7 4.0 3.6 3.8 6.1 2.0 12.8 15.1 0.3 5.9 3.7 0.2 0.9 8.6 0.0 3.1 2.8 0.9 0.0 9.7 0.0 0.0 1.5 2.1 0.2 0.0 0.1 1.7 0.2 0.1 9.3 0.0 0.0 0.1 0.0 14.1 2.4 0.0 0.1 6.3 0.0 6.1 2.1 87.2 0.0 0.1 0.0 4.1 415.2 291.5 2.2 0.3 255.5 3.6 27.2 186.1 0.0 8.2 0.0 0.0 0.0 1.1 0.0 1.1 0.1 0.0 1.3 2.4 0.4 13.1 1.1 1.0 0.1 0.5 13.2 3.0 5.3 4.1 0.0 0.0 0.5 CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 59.5;testis: 113.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 313.3;Early spermatids: 162.4;Endometrial ciliated cells: 93.4;Muller glia cells: 176.4;Spermatocytes: 465.5" "Cancer enhanced" "Detected in many" "prostate cancer: 19.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 53.0;MOLT-4: 47.8;U-251 MG: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "CAB020709: , HPA048761: AB_2680514, HPA058627: AB_2683782" "unprognostic (6.74e-2)" "unprognostic (8.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" "unprognostic (3.73e-3)" "unprognostic (6.14e-2)" "unprognostic (4.80e-2)" "unprognostic (3.11e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.45e-3)" "unprognostic (3.00e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" 0.4 6.6 0.9 1.0 0.7 2.4 2.7 3.8 1.6 0.9 2.0 2.6 0.5 1.6 0.6 1.2 13.7 0.4 59.5 0.9 2.6 0.4 3.2 0.5 0.7 2.7 1.9 0.3 2.2 0.6 11.2 0.2 2.6 22.5 1.3 17.2 1.0 0.7 0.4 0.2 1.3 1.5 1.2 0.2 2.0 113.6 2.3 2.4 2.7 1.6 1.2 0.6 0.1 0.9 0.2 10.2 10.3 6.9 4.0 21.1 2.4 0.1 9.4 10.0 18.6 0.3 0.9 0.0 27.8 0.9 8.4 0.2 7.5 0.1 16.2 0.4 9.0 3.0 9.8 7.4 41.4 38.9 0.6 2.2 39.2 1.0 0.9 53.0 0.2 9.6 2.0 0.0 0.0 0.5 47.8 0.5 12.0 0.2 28.1 31.5 0.0 0.4 0.0 0.3 16.8 29.8 6.5 4.1 1.8 3.8 1.9 5.6 0.0 27.4 4.7 9.7 73.6 14.4 31.7 19.9 43.4 1.6 2.9 0.9 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 3.8 1.6 0.9 2.6 2.7 1.9 2.6 1.2 2.3 0.9 0.8 0.0 2.2 0.3 0.1 0.0 0.9 8.5 1.2 9.2 3.3 1.8 313.3 0.0 6.4 0.0 4.2 0.5 0.0 0.5 0.0 1.2 162.4 93.4 1.3 11.9 5.3 8.6 7.2 4.2 0.1 10.2 0.0 11.3 0.0 10.1 0.7 3.7 0.1 25.2 6.7 0.4 30.5 0.0 0.0 60.2 5.0 0.7 1.8 0.0 0.1 176.4 0.0 6.6 0.6 0.9 3.9 4.5 0.1 33.8 0.2 0.1 24.6 16.3 0.0 0.6 2.0 465.5 23.9 2.8 0.1 0.3 0.7 0.2 0.8 1.3 CLIC1 "CLCNL1, G6, NCC27, p64CLCP" ENSG00000213719 "Chloride intracellular channel 1" O00299 6 31730581-31739763 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020825, CAB040557" Enhanced Supported Cytosol NA NA 22000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "CAB020825: , CAB040557: " "unprognostic (7.26e-2)" "unprognostic (9.32e-2)" "unprognostic (2.78e-3)" "unprognostic (7.29e-2)" "unprognostic (6.93e-2)" "unprognostic (2.73e-2)" "prognostic unfavorable (8.90e-7)" "unprognostic (2.58e-2)" "unprognostic (8.51e-2)" "unprognostic (8.71e-3)" "unprognostic (1.19e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (8.11e-5)" "unprognostic (4.51e-2)" "unprognostic (2.89e-1)" "unprognostic (1.35e-2)" "unprognostic (7.31e-2)" 292.8 156.5 6.9 43.4 6.8 64.0 256.7 7.1 11.0 222.2 8.7 291.6 37.0 197.9 20.9 395.9 190.5 43.7 183.7 6.7 10.2 318.5 102.6 330.4 44.1 9.4 7.7 149.8 148.1 20.1 111.5 45.5 8.9 217.0 64.0 2.6 251.3 22.3 47.3 324.8 231.6 32.7 8.9 332.6 247.8 41.0 9.6 35.2 180.8 11.1 58.1 257.7 246.8 8.9 119.5 54.1 87.0 45.6 56.6 118.6 43.3 52.8 105.4 92.6 77.9 125.2 87.2 48.7 73.6 186.0 116.9 70.2 65.8 154.9 124.4 38.9 34.4 93.0 43.4 109.3 73.0 164.3 125.9 74.3 80.5 157.0 148.4 101.7 157.9 44.6 109.4 149.5 181.0 79.2 77.2 213.2 7.7 128.9 78.4 13.5 47.5 115.3 210.2 73.0 16.5 19.5 43.1 49.1 71.5 60.4 33.7 228.3 105.0 128.6 91.2 39.0 166.8 48.3 98.3 66.0 62.4 122.0 136.6 244.3 179.4 239.3 165.6 194.3 135.8 186.1 98.0 155.5 143.8 150.3 30.5 92.3 341.1 176.3 174.3 80.5 149.2 414.2 6.9 6.8 7.1 11.0 6.7 10.2 9.4 7.7 8.9 8.9 9.6 8.9 514.8 70.5 67.0 0.7 382.5 960.8 589.1 869.7 331.2 0.4 274.3 300.5 18.6 296.0 457.7 237.3 0.0 545.5 472.2 730.7 602.6 1096.2 31.8 271.1 212.7 490.1 381.4 208.6 0.0 1008.9 912.5 296.6 370.5 301.3 554.1 431.2 300.9 54.2 1047.6 0.0 0.0 665.6 516.8 533.7 1529.8 17.3 233.9 685.7 524.7 13.1 426.4 86.8 706.5 0.5 0.0 1470.4 997.1 188.1 420.2 851.1 707.7 572.1 473.6 6.9 203.8 136.1 554.0 28.7 16.2 464.1 928.0 572.7 522.2 283.3 675.0 1005.9 CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Alveolar cells type 1: 89.8;Alveolar cells type 2: 54.9;Endothelial cells: 60.4;Erythroid cells: 70.7;Kupffer cells: 73.5;Langerhans cells: 135.0;monocytes: 71.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Group enriched" "Detected in some" 5 "HDLM-2: 103.3;K-562: 60.4;Karpas-707: 53.4;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" 23.1 7.1 6.9 16.7 7.8 9.8 16.7 6.9 18.1 20.1 7.6 10.9 8.7 22.6 7.8 9.4 12.5 19.0 14.6 7.1 7.0 5.8 12.8 30.6 30.2 7.7 6.9 21.6 3.5 4.6 4.5 9.3 7.4 4.6 13.6 2.4 6.2 6.3 4.4 6.1 10.3 17.7 7.7 50.1 8.5 3.2 8.5 14.5 31.8 14.3 25.6 15.9 10.7 7.8 0.7 0.0 1.0 0.9 1.0 4.7 0.0 0.2 2.8 0.0 0.4 0.0 0.2 0.1 0.4 0.0 0.2 0.1 0.3 0.0 0.0 103.3 0.5 16.4 0.3 0.0 0.0 0.4 0.6 1.4 0.0 0.0 0.1 0.5 0.1 0.5 60.4 53.4 0.3 0.2 0.1 1.3 0.2 0.1 0.4 0.4 0.0 92.2 0.2 0.2 0.7 0.9 0.0 0.1 0.4 0.2 0.0 1.0 0.0 5.3 1.6 2.0 0.9 3.3 4.6 0.0 2.7 2.6 1.7 0.0 3.5 0.2 0.0 18.6 0.3 0.0 0.1 0.1 47.9 0.0 0.0 0.0 1.4 2.0 14.2 5.2 0.0 2.1 6.9 7.8 6.9 18.1 7.1 7.0 7.7 6.9 7.4 7.7 8.5 7.8 51.2 89.8 54.9 3.9 1.1 13.3 0.8 0.2 2.2 1.2 0.7 1.3 3.2 0.0 5.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.5 11.3 60.4 1.2 70.7 8.6 0.2 0.1 25.6 0.5 0.4 3.8 0.5 27.1 1.2 4.7 0.0 7.0 0.6 0.0 73.5 135.0 1.1 13.7 34.5 17.8 8.4 71.4 0.2 0.0 3.0 2.4 0.1 0.0 9.4 2.0 0.5 0.0 0.6 1.5 0.3 6.6 2.5 4.6 0.3 0.3 0.4 13.8 0.0 2.6 5.2 0.1 1.9 CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 346.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.4;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome" NA NA 5800000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Centrosome" "HPA008019: AB_1846946, HPA060804: AB_2684370" "unprognostic (7.35e-3)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.54e-2)" "unprognostic (7.60e-2)" "unprognostic (2.92e-2)" "unprognostic (9.48e-2)" "unprognostic (6.78e-3)" "unprognostic (1.63e-2)" "unprognostic (5.50e-2)" "unprognostic (4.03e-3)" "unprognostic (1.98e-2)" "unprognostic (7.01e-2)" "prognostic favorable (1.48e-5)" "unprognostic (2.75e-3)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (3.82e-3)" 154.0 58.6 51.8 97.7 70.2 32.3 88.1 61.8 82.7 165.4 39.4 136.3 32.4 201.5 84.6 119.3 103.0 106.5 197.2 50.8 66.5 256.8 72.3 114.6 51.0 73.6 68.0 46.0 49.7 29.3 14.1 120.6 67.0 112.8 66.8 53.1 49.4 152.8 30.7 33.6 54.2 280.4 62.4 43.1 80.0 34.2 88.9 59.6 47.6 53.2 56.4 156.1 73.4 91.4 219.3 25.3 222.7 176.8 299.1 645.6 116.7 561.0 571.4 253.9 304.2 48.3 114.1 129.8 320.1 799.2 77.0 76.8 155.0 151.5 635.7 33.3 64.9 50.0 60.8 88.3 417.3 17.5 6.3 299.3 256.8 363.0 365.1 417.3 427.0 76.0 40.4 138.2 739.0 38.4 34.8 28.5 212.6 50.4 101.8 83.5 247.3 51.5 260.0 58.4 38.9 101.3 144.7 68.4 453.7 228.3 60.0 116.1 601.0 452.2 168.8 199.4 230.1 75.4 111.7 108.6 333.8 151.1 140.5 0.8 5.4 2.5 0.4 4.4 0.0 13.4 0.3 0.2 5.6 11.9 0.1 0.2 1.2 0.0 4.0 1.7 0.0 3.5 51.8 70.2 61.8 82.7 50.8 66.5 73.6 68.0 67.0 62.4 88.9 91.4 178.7 16.0 30.5 24.8 50.8 61.6 50.4 79.8 37.0 3.7 49.9 33.0 172.5 21.5 35.2 14.7 10.4 71.5 2.2 18.1 41.1 39.2 44.9 20.9 103.0 177.1 9.6 40.8 1.5 43.1 211.4 120.5 21.4 53.6 40.0 10.2 88.5 34.4 39.3 1.7 4.2 22.6 20.3 28.2 100.2 27.3 28.6 52.6 129.9 75.9 50.8 13.0 4.1 41.7 196.9 54.7 10.6 87.6 171.2 114.5 0.1 346.1 16.7 26.5 46.0 87.9 162.5 44.0 29.1 29.3 52.0 177.0 8.1 46.5 2.6 49.1 CLN8 "C8orf61, EPMR, FLJ39417, TLCD6" ENSG00000182372 "CLN8 transmembrane ER and ERGIC protein" Q9UBY8 8 1755778-1801711 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 136.8;Syncytiotrophoblasts: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 76.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 76.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "unprognostic (5.86e-2)" "unprognostic (1.95e-2)" "unprognostic (6.40e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (4.05e-3)" "unprognostic (1.21e-1)" "unprognostic (3.45e-1)" "unprognostic (3.03e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-3)" "unprognostic (1.83e-1)" "prognostic favorable (4.36e-8)" "unprognostic (1.36e-1)" "unprognostic (1.70e-1)" "unprognostic (6.24e-2)" "unprognostic (8.38e-2)" 5.4 5.2 11.4 3.7 15.7 9.1 4.3 14.6 12.4 4.7 6.6 4.9 5.0 3.2 11.2 9.8 3.3 7.5 6.2 10.6 11.3 6.2 8.9 8.9 6.5 18.2 15.2 2.5 10.1 8.0 3.5 6.0 18.5 3.8 4.4 3.8 5.1 3.6 5.9 13.2 6.3 4.0 16.9 7.9 6.8 5.9 15.1 3.2 5.1 3.3 7.2 4.4 5.8 24.3 3.6 8.5 6.2 6.5 8.3 8.4 14.8 8.3 5.1 4.2 5.2 8.6 10.0 4.4 2.3 8.2 5.6 13.7 4.9 15.6 8.6 3.3 3.6 4.4 3.2 4.9 4.7 3.7 19.1 8.4 12.2 5.8 4.1 10.1 9.2 3.2 6.0 2.6 13.1 9.0 6.0 3.2 6.1 14.0 7.3 4.2 4.3 3.4 7.8 15.4 3.2 3.9 3.5 8.1 4.6 12.7 16.2 4.2 17.3 11.3 3.2 0.9 5.2 1.5 5.4 5.0 11.4 7.3 16.9 7.4 10.6 4.7 6.4 13.6 7.1 10.3 6.9 4.5 10.6 14.0 6.7 4.4 3.7 5.1 12.5 76.7 8.0 6.4 11.4 15.7 14.6 12.4 10.6 11.3 18.2 15.2 18.5 16.9 15.1 24.3 18.3 9.6 17.5 6.2 30.1 54.7 71.6 38.6 26.7 27.6 23.4 13.2 7.7 20.0 37.2 31.3 31.3 38.0 115.3 28.5 15.6 27.2 5.4 20.5 6.9 34.7 19.7 40.8 7.4 19.0 18.0 32.7 13.7 37.2 27.3 17.1 27.8 28.5 44.1 40.4 7.6 17.5 50.8 54.6 136.8 5.9 8.1 69.8 21.4 8.4 22.3 13.9 23.7 10.1 27.1 19.3 20.7 12.0 9.1 76.5 19.5 10.6 27.1 26.1 13.1 22.5 16.8 34.4 23.5 20.1 63.5 131.6 22.0 16.1 15.4 61.2 CLPSL2 "C6orf126, dJ510O8.5, UNQ3045" ENSG00000196748 "Colipase like 2" Q6UWE3 6 35776594-35779552 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "epididymis: 532.1" "Group enriched" "Detected in some" 4 "Breast glandular cells: 3.4;Breast myoepithelial cells: 2.2;Enteroendocrine cells: 1.8;Exocrine glandular cells: 4.0;Pancreatic endocrine cells: 2.1;Spermatogonia: 2.2" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "T-47d: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA051655 Approved "Secreted in male reproductive system" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 1: Pancreatic cells - Digestion" "HPA051655: " "unprognostic (2.38e-1)" "unprognostic (3.65e-1)" "unprognostic (6.39e-3)" "unprognostic (9.38e-2)" "unprognostic (4.03e-2)" "unprognostic (2.47e-1)" "unprognostic (4.85e-3)" "unprognostic (8.69e-2)" "unprognostic (3.17e-2)" "unprognostic (3.95e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-1)" "unprognostic (2.37e-1)" 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.2 0.8 0.0 0.2 0.0 0.0 0.0 532.1 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.4 0.0 5.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.7 0.7 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.2 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.7 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.3 0.0 0.1 6.3 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.4 0.2 0.8 0.6 0.4 0.2 0.4 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 2.2 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 1.8 0.0 0.2 4.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 CLSPN ENSG00000092853 Claspin Q9HAW4 1 35720218-35769978 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.3;lymphoid tissue: 7.9;retina: 6.8;testis: 5.7" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 101.0;Spermatocytes: 281.1;Spermatogonia: 263.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Region enriched" "Detected in some" 6 "basal ganglia: 7.8" "Low region specificity" "Detected in many" "HPA026305, HPA026312" Enhanced "Nucleoplasm,Golgi apparatus" Yes Yes "Cluster 17: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA026305: AB_2671833, HPA026312: AB_2671837" "unprognostic (4.75e-2)" "unprognostic (1.01e-1)" "unprognostic (9.64e-3)" "unprognostic (3.54e-2)" "unprognostic (6.82e-2)" "unprognostic (1.62e-2)" "unprognostic (1.18e-6)" "unprognostic (3.99e-3)" "unprognostic (2.08e-3)" "unprognostic (1.63e-2)" "unprognostic (8.71e-6)" "unprognostic (3.23e-2)" "unprognostic (7.61e-6)" "prognostic favorable (4.92e-4)" "unprognostic (5.12e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" 0.5 0.2 0.7 3.2 0.6 11.3 0.5 0.6 1.4 0.2 0.4 1.4 1.0 0.4 0.7 0.9 0.2 0.3 0.1 1.3 0.3 0.2 0.5 0.4 4.9 0.4 0.4 0.1 0.1 0.2 0.0 1.5 0.6 0.2 2.0 6.8 0.2 0.1 0.6 1.2 1.0 0.9 0.2 1.3 0.9 5.7 0.6 7.9 0.2 0.0 5.2 0.6 0.4 0.9 22.0 17.5 37.8 19.9 2.6 4.8 14.1 43.6 12.0 31.0 41.3 27.9 19.6 45.7 13.9 11.8 22.7 21.4 37.1 14.9 48.1 31.6 16.8 64.5 38.1 12.6 0.1 54.0 36.8 1.0 0.6 53.8 3.7 3.7 16.9 27.1 44.2 30.8 30.3 14.1 56.9 13.1 36.0 14.9 12.2 36.0 57.0 13.8 6.4 35.3 14.0 16.2 37.7 11.6 7.4 25.6 10.0 21.1 12.5 44.6 33.8 27.6 49.3 11.1 29.1 47.1 14.1 37.4 37.0 1.1 0.3 0.3 0.3 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.2 1.0 0.5 0.2 0.2 0.3 0.3 0.7 0.6 0.6 1.4 1.3 0.3 0.4 0.4 0.6 0.2 0.6 0.9 2.6 0.0 0.5 0.3 6.5 5.6 5.7 4.4 1.2 9.4 2.9 3.8 1.4 2.8 2.7 0.0 12.5 19.7 4.6 12.8 0.0 1.6 7.9 1.0 3.6 3.6 1.2 55.6 1.6 0.6 41.1 5.2 4.6 3.3 1.3 12.0 2.2 0.4 16.9 1.7 1.5 9.4 2.0 3.0 8.2 6.1 2.5 5.8 3.6 0.0 9.1 9.4 4.1 0.0 0.6 1.4 9.5 0.4 32.5 1.8 0.4 0.2 0.0 101.0 6.6 5.3 8.7 281.1 263.3 5.8 2.0 10.4 7.2 1.2 12.0 3.9 CLSTN1 "CDHR12, CSTN1, KIAA0911" ENSG00000171603 "Calsyntenin 1" O94985 1 9728926-9823984 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 437.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012412, HPA077705" Enhanced NA NA 86000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA012412: AB_1846981, HPA077705: " "unprognostic (4.63e-2)" "unprognostic (2.89e-1)" "unprognostic (9.76e-2)" "unprognostic (1.43e-1)" "unprognostic (9.79e-2)" "unprognostic (1.63e-1)" "unprognostic (2.44e-3)" "unprognostic (3.07e-2)" "unprognostic (2.54e-1)" "unprognostic (3.24e-2)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" "prognostic favorable (4.10e-7)" "unprognostic (1.12e-1)" "unprognostic (2.65e-1)" "unprognostic (4.05e-2)" "unprognostic (4.72e-2)" 28.1 27.4 49.7 23.1 65.8 10.8 31.7 29.5 137.5 61.2 80.6 59.5 29.2 85.4 21.4 51.4 69.8 48.1 35.9 79.6 15.5 41.3 6.1 29.6 33.5 24.7 18.4 60.2 65.7 36.2 48.4 35.7 32.8 61.8 38.2 110.8 79.0 45.7 23.1 83.5 41.1 49.4 7.0 28.3 31.0 15.0 23.5 35.0 40.0 28.9 27.1 38.0 59.9 45.9 120.9 55.4 52.5 64.8 71.1 50.1 35.0 80.5 71.4 82.0 70.2 32.1 235.0 90.5 203.1 95.2 52.6 157.7 41.2 245.6 32.1 114.2 74.6 27.3 53.0 39.6 116.1 46.3 41.4 58.0 156.5 105.9 50.0 78.6 113.9 52.7 13.1 52.6 35.8 47.2 53.2 26.6 37.9 53.1 59.7 80.6 21.4 42.9 73.1 20.9 91.4 53.7 94.8 160.1 79.1 22.1 34.7 73.9 155.0 89.3 80.5 56.6 109.9 75.6 75.4 124.3 72.2 79.6 95.7 6.2 0.6 2.3 3.0 0.8 1.5 0.8 1.9 2.3 1.4 1.0 1.3 1.2 0.2 0.4 0.9 0.8 1.6 1.5 49.7 65.8 29.5 137.5 79.6 15.5 24.7 18.4 32.8 7.0 23.5 45.9 40.2 28.9 15.7 63.6 23.7 43.8 61.0 73.7 84.2 205.1 53.3 47.0 14.7 55.8 44.6 51.5 437.9 34.1 35.0 221.1 1.9 29.2 4.5 44.6 47.0 36.0 30.7 17.9 150.9 38.8 14.3 40.6 29.6 52.2 11.4 54.0 35.3 2.2 28.8 180.0 138.1 96.5 14.2 24.2 13.3 5.6 46.3 21.3 32.0 46.9 21.0 160.9 28.8 90.0 56.0 59.7 66.9 50.4 31.2 42.4 54.9 27.9 68.3 165.6 85.5 39.5 31.4 24.6 37.5 44.5 26.1 19.2 33.8 47.2 59.6 42.7 CLSTN3 "CDHR14, CSTN3, KIAA0726" ENSG00000139182 "Calsyntenin 3" Q9BQT9 12 7129698-7158945 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 161.2;Cone photoreceptor cells: 62.6;Excitatory neurons: 79.4;Inhibitory neurons: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 6.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1700000 "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "prognostic favorable (5.08e-4)" "unprognostic (2.84e-2)" "unprognostic (1.06e-3)" "unprognostic (1.33e-2)" "unprognostic (6.73e-3)" "unprognostic (6.35e-2)" "unprognostic (9.52e-2)" "unprognostic (2.58e-1)" "unprognostic (2.94e-1)" "unprognostic (1.85e-1)" "prognostic favorable (1.19e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.49e-5)" "unprognostic (2.19e-2)" "unprognostic (6.14e-2)" "unprognostic (1.91e-1)" "prognostic favorable (8.07e-4)" 12.9 14.5 23.1 13.6 20.8 12.4 13.3 18.6 42.7 13.4 0.0 8.3 6.8 11.0 2.7 6.8 11.7 10.1 7.0 21.1 33.9 21.2 29.2 12.7 14.3 13.5 7.7 25.4 10.4 11.2 30.3 3.7 24.8 9.6 3.9 20.2 11.0 4.4 2.5 10.5 14.2 7.3 0.7 20.7 7.5 4.3 22.3 10.2 12.4 1.6 9.0 9.9 9.6 14.0 6.7 11.2 4.3 10.3 4.7 5.2 30.1 3.9 9.4 7.1 12.1 18.3 10.1 12.1 2.9 6.0 9.1 8.4 6.7 8.0 3.5 10.9 7.5 19.2 19.9 18.6 5.9 2.7 34.6 15.2 5.9 8.5 7.4 30.6 9.1 11.2 19.0 6.6 1.3 2.4 8.3 2.8 12.6 0.6 0.7 5.3 0.1 3.5 10.7 13.8 5.6 9.2 8.4 9.5 1.7 10.4 5.4 7.0 4.6 3.9 13.6 8.6 2.4 8.7 2.2 1.6 7.6 3.2 2.8 1.5 0.0 0.0 3.3 0.0 1.9 0.1 1.5 2.9 0.1 0.1 0.5 1.2 0.2 6.9 0.0 0.0 2.0 1.0 23.1 20.8 18.6 42.7 21.1 33.9 13.5 7.7 24.8 0.7 22.3 14.0 6.0 0.0 3.9 5.2 2.8 4.1 2.3 4.9 7.4 161.2 15.7 7.5 2.3 4.3 3.3 14.7 62.6 5.4 14.1 2.9 0.0 9.2 1.2 3.3 18.0 15.3 29.3 1.3 79.4 7.5 9.3 12.0 7.7 6.3 5.7 8.6 5.7 26.6 1.2 26.9 60.2 4.0 16.2 2.0 7.3 1.9 12.8 3.6 5.4 4.7 1.1 9.5 13.4 10.6 3.1 7.2 3.2 6.4 12.7 1.9 1.3 23.3 3.0 40.3 6.6 5.1 6.8 0.7 1.1 2.7 5.7 3.3 16.6 6.8 3.6 1.8 CLVS2 "bA160A10.4, C6orf212, C6orf213, RLBP1L2" ENSG00000146352 "Clavesin 2" Q5SYC1 6 122996235-123072925 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 41.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 137.8;Inhibitory neurons: 171.5;Muller glia cells: 60.8" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Region enriched" "Detected in many" 4 "cerebellum: 41.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HEL: 12.2;SCLC-21H: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043764 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043764: AB_10960281" "unprognostic (1.35e-1)" "unprognostic (3.28e-2)" "unprognostic (4.68e-2)" "unprognostic (3.60e-1)" "unprognostic (2.38e-1)" "unprognostic (7.04e-2)" "unprognostic (1.43e-2)" "unprognostic (5.72e-3)" "unprognostic (9.60e-2)" "unprognostic (8.71e-2)" 0.0 0.9 5.8 0.0 5.7 0.0 0.0 41.1 9.2 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 5.8 8.5 0.0 0.0 0.0 0.0 5.3 0.3 0.0 0.0 0.0 1.9 0.0 5.2 3.0 0.1 8.2 0.0 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 0.2 1.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.7 41.1 9.2 5.8 8.5 5.3 0.3 5.2 0.0 0.2 1.9 0.4 0.0 0.0 22.2 0.0 0.0 17.9 0.0 0.0 5.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.9 0.0 0.0 0.3 0.0 0.0 137.8 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 171.5 0.0 0.0 0.0 0.0 0.7 0.3 0.2 0.0 2.8 0.0 60.8 0.0 27.2 4.0 0.0 0.0 0.4 0.0 4.6 0.0 0.0 0.0 4.8 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.6 CMIP ENSG00000153815 "C-Maf inducing protein" Q8IY22 16 81444808-81711762 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.0;neutrophil: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HMC-1: 180.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054424, HPA066710" Approved Supported Nucleoplasm,Cytosol NA NA 83000 "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Cytosol" "HPA054424: AB_2682484, HPA066710: AB_2685708" "unprognostic (6.84e-2)" "unprognostic (1.99e-1)" "unprognostic (2.89e-2)" "unprognostic (3.76e-1)" "unprognostic (3.02e-2)" "unprognostic (9.83e-3)" "unprognostic (2.28e-2)" "prognostic unfavorable (9.47e-7)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (3.10e-2)" "unprognostic (6.04e-2)" "unprognostic (4.12e-2)" "unprognostic (3.42e-2)" "unprognostic (9.08e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.59e-1)" 27.9 22.1 45.2 32.1 46.2 26.1 23.2 12.6 50.1 30.7 0.0 26.5 40.4 18.8 6.1 35.8 23.0 25.6 13.0 48.8 51.1 20.7 13.5 26.3 22.2 29.9 34.8 22.8 19.3 7.8 55.6 28.4 46.1 17.7 23.1 10.8 20.1 15.0 4.7 34.3 49.9 22.5 19.9 22.5 33.3 17.2 52.7 20.1 15.6 5.3 18.2 31.2 32.8 34.4 40.9 133.5 25.9 13.3 13.4 10.7 52.7 28.9 19.5 17.9 7.9 45.5 81.5 18.2 24.2 24.1 23.9 40.6 16.9 96.2 17.0 11.6 12.3 87.4 24.4 80.0 13.3 27.2 180.8 10.5 39.9 33.1 42.5 27.1 50.0 31.7 77.6 15.3 11.1 40.9 47.7 33.8 20.6 39.5 28.1 84.9 8.5 17.8 22.6 39.7 135.0 27.1 67.4 24.7 8.6 25.9 19.1 35.7 34.6 28.5 30.6 27.7 26.8 19.2 15.9 78.0 33.6 31.5 11.7 3.0 0.7 1.0 0.4 0.5 0.2 0.0 0.1 0.1 0.2 0.3 0.0 0.2 2.4 0.2 0.1 0.2 0.1 0.4 45.2 46.2 12.6 50.1 48.8 51.1 29.9 34.8 46.1 19.9 52.7 34.4 81.5 12.8 16.6 59.4 31.7 107.3 66.6 43.8 48.9 15.6 21.5 21.1 7.8 47.1 27.7 14.7 0.0 46.5 71.2 58.0 7.9 22.3 70.0 51.1 9.2 77.3 72.1 17.9 119.1 23.8 106.6 25.7 35.7 45.4 45.1 29.8 70.6 31.6 32.0 25.2 95.2 128.0 40.7 69.4 115.9 100.8 47.5 95.5 12.4 100.2 68.2 8.0 37.0 69.9 52.9 65.5 30.9 143.3 35.2 69.6 47.3 49.6 57.6 3.4 13.1 8.0 24.1 5.0 15.4 51.8 143.5 88.7 42.8 6.4 39.1 111.7 CMTM5 "CKLFSF5, FLJ37521" ENSG00000166091 "CKLF like MARVEL transmembrane domain containing 5" Q96DZ9 14 23376773-23379772 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 182.4;choroid plexus: 49.5" "Cell type enhanced" "Detected in some" "Macrophages: 93.7;Muller glia cells: 32.0;Oligodendrocyte precursor cells: 20.6;Oligodendrocytes: 106.2" "Group enriched" "Detected in some" 37 "glioma: 8.4;melanoma: 3.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 20.8" "Lineage enriched" "Detected in many" 19 "granulocytes: 20.8" "Cell line enriched" "Detected in some" 7 "HEL: 91.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052338 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 540000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Vesicles" "HPA052338: AB_2681793" "unprognostic (2.73e-3)" "unprognostic (1.51e-1)" "unprognostic (5.24e-1)" "unprognostic (2.43e-3)" "unprognostic (2.63e-1)" "unprognostic (6.40e-2)" "unprognostic (8.34e-3)" "unprognostic (1.78e-1)" "unprognostic (2.27e-2)" "unprognostic (8.40e-2)" "unprognostic (6.24e-4)" "unprognostic (3.03e-3)" "unprognostic (1.97e-3)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.11e-2)" 1.1 1.0 75.6 0.5 119.1 8.2 0.9 123.8 101.7 2.8 49.5 5.8 0.5 0.8 1.1 1.2 1.2 2.1 22.7 73.9 85.2 0.5 0.3 1.5 0.2 150.9 106.2 0.8 0.2 0.1 0.6 0.7 135.2 2.1 0.8 2.3 2.2 3.2 3.1 0.7 1.7 0.8 113.4 2.8 1.4 0.1 110.2 0.1 0.5 0.9 0.0 1.2 2.6 182.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 91.8 0.0 0.0 0.2 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.2 20.8 0.7 0.9 0.1 0.4 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 4.2 0.0 0.0 1.0 0.4 30.0 75.6 119.1 123.8 101.7 73.9 85.2 150.9 106.2 135.2 113.4 110.2 182.4 0.5 0.0 0.0 6.5 0.4 1.0 0.1 0.0 1.2 0.2 1.3 5.5 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.4 0.0 0.0 93.7 5.4 0.0 1.5 32.0 0.0 20.6 106.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.6 3.4 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.1 CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534500-74587212 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 85.6" "Cell type enriched" "Detected in some" 10 "Oligodendrocytes: 361.7" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 38 "U-266/84: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008933, HPA073283" Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 70: Brain - Nervous system development" "Cluster 16: U-266 - Nucleosome" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008933: AB_1847033, HPA073283: " "unprognostic (7.43e-3)" "unprognostic (6.00e-2)" "unprognostic (8.55e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (6.90e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" 0.0 0.0 27.4 0.0 74.2 0.1 0.0 80.4 39.0 0.0 6.0 0.0 1.3 0.0 0.7 0.0 0.0 0.1 0.0 30.5 51.3 0.5 12.9 0.0 0.0 85.6 76.9 0.0 0.0 0.0 0.2 0.0 74.3 0.1 0.0 0.1 0.0 0.1 1.4 0.1 0.2 0.0 39.7 0.0 0.0 0.3 74.9 0.0 0.2 0.0 0.0 0.0 0.0 80.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 15.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 27.4 74.2 80.4 39.0 30.5 51.3 85.6 76.9 74.3 39.7 74.9 80.7 0.2 0.0 0.0 0.3 0.2 0.1 0.4 0.2 0.0 0.6 0.5 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 8.6 0.5 0.2 0.2 0.0 2.7 1.2 0.2 0.0 0.3 0.0 1.5 0.0 0.2 0.7 35.1 0.1 0.0 1.5 0.7 0.0 1.2 1.1 3.1 0.0 0.2 0.0 1.0 0.0 0.5 0.0 3.0 361.7 0.2 0.1 0.0 0.0 0.4 0.4 24.5 0.0 1.0 0.0 0.6 0.2 1.0 0.4 0.0 0.3 0.0 0.4 0.0 0.5 0.2 CNFN PLAC8L2 ENSG00000105427 Cornifelin Q9BYD5 19 42387019-42390297 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 952.0;esophagus: 3093.3;vagina: 1442.7" "Cell type enhanced" "Detected in many" "Breast glandular cells: 57.9;Breast myoepithelial cells: 51.6;Squamous epithelial cells: 71.8" "Cancer enhanced" "Detected in all" "head and neck cancer: 367.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "memory B-cell: 61.2;naive B-cell: 70.2" "Lineage enriched" "Detected in many" 12 "B-cells: 70.2" "Cell line enhanced" "Detected in many" "A549: 18.1;HEK 293: 25.7;MCF7: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA049073, HPA053997" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Microtubules "Cytokinetic bridge" "HPA049073: AB_2680620, HPA053997: AB_2682337" "unprognostic (5.08e-2)" "unprognostic (4.21e-3)" "unprognostic (2.52e-1)" "unprognostic (7.22e-2)" "unprognostic (3.15e-2)" "unprognostic (8.35e-3)" "unprognostic (6.04e-2)" "unprognostic (2.06e-3)" "unprognostic (3.52e-1)" "unprognostic (9.44e-2)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (8.42e-2)" "unprognostic (4.83e-2)" "unprognostic (7.77e-3)" "prognostic favorable (4.02e-5)" "unprognostic (2.45e-1)" 4.3 5.3 1.8 0.4 4.2 0.6 12.9 1.9 2.2 952.0 1.3 3.2 0.4 1.5 7.3 3093.3 1.6 0.1 1.9 1.9 2.8 2.3 1.4 0.9 0.7 2.1 1.9 1.0 3.3 1.6 2.2 0.1 1.7 8.6 1.3 0.1 661.6 1.1 1.7 555.6 3.5 0.5 1.7 3.3 3.3 2.4 2.9 2.8 1.8 0.0 276.8 2.4 1442.7 1.6 6.0 18.1 0.4 1.6 0.8 0.9 0.2 1.0 0.3 0.4 0.4 1.0 1.6 5.1 8.0 0.2 1.2 2.4 1.5 2.3 0.1 0.0 25.7 0.4 6.9 1.9 0.0 0.0 0.1 1.8 4.0 1.0 0.0 0.1 0.0 4.7 1.1 0.2 0.0 12.6 0.1 0.1 6.6 8.1 5.4 2.2 0.3 2.9 1.6 2.3 2.7 7.7 3.4 5.1 2.5 2.7 6.2 2.6 0.0 0.0 5.3 0.2 0.1 5.8 7.6 3.6 0.1 2.2 0.3 0.1 4.6 0.1 1.7 3.9 0.4 61.2 1.3 1.2 5.9 70.2 0.6 0.9 1.3 0.0 0.9 1.3 0.1 2.2 1.8 4.2 1.9 2.2 1.9 2.8 2.1 1.9 1.7 1.7 2.9 1.6 32.7 3.2 2.2 0.0 24.6 4.6 16.8 28.5 14.8 0.1 57.9 51.6 0.8 2.8 20.2 33.1 0.0 0.2 2.1 24.5 7.9 13.1 1.5 20.6 3.9 9.3 32.5 3.6 0.1 2.5 0.3 2.3 4.6 23.9 4.5 7.2 3.9 0.7 5.7 0.0 0.2 33.4 14.2 3.8 7.7 3.9 5.3 6.3 3.6 0.0 6.4 0.3 7.2 0.0 0.1 2.4 39.4 4.5 0.5 11.5 43.8 12.3 10.5 0.1 0.0 0.9 8.0 0.4 17.4 71.8 12.9 0.3 1.3 1.1 41.8 27.0 CNGB1 "CNCG2, CNCG3L, CNGB1B, GAR1, GARP, RCNC2, RCNCb, RP45" ENSG00000070729 "Cyclic nucleotide gated channel subunit beta 1" Q14028 16 57882340-57971128 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Olfaction, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "retina: 600.2" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 331.5;Rod photoreceptor cells: 1111.1" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.5;RPMI-8226: 1.8;SCLC-21H: 5.0;SiHa: 2.9;SK-BR-3: 1.4" "Region enhanced" "Detected in some" "hypothalamus: 4.5" "HPA039159, HPA060355" Approved Vesicles,Cytosol No NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Vesicles "HPA039159: AB_10795579, HPA060355: " "unprognostic (5.52e-3)" "unprognostic (4.51e-3)" "unprognostic (1.06e-1)" "unprognostic (2.73e-3)" "unprognostic (6.20e-2)" "unprognostic (1.76e-1)" "unprognostic (8.56e-4)" "unprognostic (3.08e-1)" "unprognostic (9.84e-2)" "unprognostic (2.83e-1)" "unprognostic (2.14e-4)" "unprognostic (5.42e-2)" "unprognostic (1.01e-3)" "unprognostic (5.20e-2)" "unprognostic (1.88e-1)" "unprognostic (4.57e-2)" "unprognostic (9.07e-2)" 0.1 2.5 15.5 1.1 13.2 0.2 0.0 0.0 20.4 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.1 0.3 0.0 24.5 24.8 0.0 0.1 0.1 0.2 2.8 3.2 0.0 0.5 0.0 0.2 0.4 4.4 0.0 0.4 600.2 0.0 0.1 0.0 0.2 0.6 0.1 2.4 0.1 0.0 0.4 36.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.5 0.0 0.5 0.0 0.0 1.3 0.0 0.1 0.0 0.3 0.9 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 1.8 0.0 0.6 5.0 0.0 2.9 1.4 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.2 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 15.5 13.2 0.0 20.4 24.5 24.8 2.8 3.2 4.4 2.4 36.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.4 0.0 61.6 0.3 0.0 1.1 0.0 0.1 0.0 331.5 6.9 0.0 0.0 0.0 0.4 1.6 0.9 0.1 4.2 0.0 0.0 3.2 0.4 0.9 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.4 25.2 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 89.5 0.0 1.0 0.1 0.2 1.1 0.0 0.0 0.2 0.0 0.3 0.0 1111.1 0.0 0.1 0.2 0.5 0.7 0.0 0.0 1.4 0.1 0.1 0.0 0.2 CNKSR2 "CNK2, KIAA0902, KSR2" ENSG00000149970 "Connector enhancer of kinase suppressor of Ras 2" Q8WXI2 X 21372801-21654695 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 22.6;retina: 17.9" "Cell type enhanced" "Detected in many" "Astrocytes: 111.7;Excitatory neurons: 497.7;Inhibitory neurons: 143.6;Oligodendrocyte precursor cells: 93.5;Rod photoreceptor cells: 86.1" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.9;AF22: 4.0;NTERA-2: 8.9;PC-3: 4.8;RH-30: 8.2;U-251 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001502 Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 58: Brain - Synaptic function" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" "HPA001502: AB_1078542" "unprognostic (1.33e-2)" "unprognostic (1.00e-3)" "unprognostic (5.35e-2)" "unprognostic (4.90e-4)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (4.35e-3)" "unprognostic (2.58e-2)" "unprognostic (3.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.35e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "unprognostic (2.72e-2)" "unprognostic (3.93e-2)" "unprognostic (2.27e-2)" "unprognostic (4.13e-2)" 1.5 2.6 8.4 0.3 12.2 0.2 1.4 22.6 16.4 1.0 0.0 0.7 0.1 0.3 0.5 0.0 1.3 0.1 0.8 20.3 0.0 0.1 0.7 1.2 0.9 0.0 0.0 0.6 2.5 0.0 1.6 0.1 0.0 0.7 0.0 17.9 0.5 0.1 4.7 0.8 0.6 0.1 0.0 0.5 1.2 0.6 0.0 0.9 0.9 1.3 1.0 0.6 0.9 5.3 0.0 5.9 4.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 2.0 0.0 8.9 0.0 4.8 0.0 8.2 0.0 0.0 0.0 3.9 1.6 0.0 0.1 0.3 2.1 0.0 0.6 0.0 0.1 1.9 0.0 5.3 3.1 0.0 3.4 0.8 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.9 0.8 0.2 0.0 0.0 0.0 0.0 0.2 0.1 8.4 12.2 22.6 16.4 20.3 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.3 16.0 1.3 111.7 9.0 1.3 0.5 0.0 1.2 17.8 0.3 0.6 5.7 1.5 5.6 0.0 20.9 0.1 2.1 0.4 0.0 0.3 0.3 1.0 13.6 0.3 0.0 0.8 497.7 2.3 0.0 6.7 0.0 1.3 1.3 1.0 0.0 2.1 0.1 23.5 143.6 0.5 0.0 0.0 2.6 0.0 0.6 0.2 0.0 15.9 0.2 12.7 0.0 93.5 10.6 0.6 0.1 1.5 3.1 2.0 1.3 0.3 0.0 86.1 0.0 0.6 0.9 6.0 7.7 0.1 1.8 0.0 2.9 1.5 0.4 0.0 CNKSR3 "FLJ31349, MAGI1" ENSG00000153721 "CNKSR family member 3" Q6P9H4 6 154387515-154510685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.6;Glandular and luminal cells: 155.4;Oligodendrocytes: 142.3;Skeletal myocytes: 211.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 21.1" "CAB037133, HPA049651" Approved Supported Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" Cytosol Mitochondria "CAB037133: AB_477217, HPA049651: AB_2680841" "unprognostic (3.07e-1)" "unprognostic (3.25e-2)" "unprognostic (1.57e-1)" "unprognostic (2.34e-1)" "unprognostic (5.62e-2)" "unprognostic (1.25e-2)" "unprognostic (1.37e-1)" "unprognostic (5.78e-2)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-3)" "unprognostic (4.90e-2)" "prognostic favorable (6.00e-4)" "unprognostic (4.23e-2)" "unprognostic (8.79e-2)" "unprognostic (1.57e-3)" "unprognostic (3.38e-1)" 3.7 1.1 6.4 1.9 7.6 0.9 3.2 4.8 5.5 4.0 15.0 6.5 5.8 7.6 1.9 13.3 4.1 4.9 6.4 3.6 4.2 7.7 9.7 3.7 1.4 7.8 8.3 6.1 18.9 0.7 2.3 5.6 7.2 3.3 3.4 2.6 5.7 4.8 1.1 3.9 6.4 6.6 5.3 4.5 4.0 4.4 12.7 2.1 2.1 1.4 2.5 4.3 5.3 13.3 0.4 4.9 3.3 6.8 5.8 4.1 0.4 6.0 3.5 10.2 8.3 21.1 0.5 0.1 6.4 6.6 3.4 2.1 9.5 0.7 5.3 0.0 6.3 15.4 1.0 12.1 2.5 0.0 2.7 6.1 3.2 3.9 4.1 1.6 3.2 1.3 2.2 0.1 2.8 1.2 0.1 0.2 2.3 4.1 6.2 4.6 5.9 8.0 11.7 3.1 2.0 12.6 2.8 1.5 1.3 1.4 0.0 1.3 3.7 0.9 3.0 7.7 4.0 0.1 0.0 0.2 0.2 0.3 4.4 0.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.1 0.1 0.2 0.0 0.0 6.4 7.6 4.8 5.5 3.6 4.2 7.8 8.3 7.2 5.3 12.7 13.3 24.7 12.8 38.4 9.4 0.9 26.5 15.4 7.8 12.5 2.0 11.0 8.3 33.8 30.0 20.2 25.8 0.0 9.2 0.4 31.0 9.8 20.3 42.5 109.6 14.7 66.8 43.2 15.6 23.8 12.3 1.1 12.9 9.2 155.4 5.7 10.8 61.8 65.9 1.7 0.0 1.5 18.4 10.2 7.1 22.5 23.6 5.9 3.5 32.0 24.4 0.8 22.8 0.0 54.8 142.3 7.3 18.5 10.5 0.5 18.7 43.6 31.8 11.7 2.5 0.0 211.8 8.0 1.2 6.3 29.4 23.9 21.5 2.6 14.8 14.1 10.0 CNN1 "Sm-Calp, SMCC" ENSG00000130176 "Calponin 1" P51911 19 11538767-11550323 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 1872.4;intestine: 2657.3;smooth muscle: 2207.8" "Group enriched" "Detected in many" 5 "Breast myoepithelial cells: 191.0;Early spermatids: 335.0;Late spermatids: 554.6;Peritubular cells: 221.2;Smooth muscle cells: 180.9" "Cancer enhanced" "Detected in all" "prostate cancer: 142.1;stomach cancer: 103.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 91.5;BJ hTERT+: 34.9;BJ hTERT+ SV40 Large T+: 48.0;BJ hTERT+ SV40 Large T+ RasG12V: 64.6;HBF TERT88: 71.2;K-562: 35.8;SuSa: 72.5;U-2 OS: 34.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000007, HPA014263" Enhanced Approved "Actin filaments" No No "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Actin filaments" "CAB000007: AB_2082148, HPA014263: AB_1847039" "unprognostic (4.98e-3)" "unprognostic (1.01e-1)" "unprognostic (3.04e-3)" "unprognostic (1.95e-1)" "unprognostic (2.47e-1)" "unprognostic (4.20e-1)" "unprognostic (5.10e-3)" "unprognostic (1.76e-1)" "unprognostic (1.35e-1)" "unprognostic (7.06e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (5.43e-6)" "unprognostic (1.70e-2)" "unprognostic (1.07e-1)" "unprognostic (2.78e-3)" "unprognostic (6.11e-3)" 115.6 58.4 6.4 160.6 8.3 0.0 89.7 5.7 14.2 366.9 7.5 2657.3 136.3 1872.4 177.0 677.5 655.6 234.3 274.1 6.8 8.5 42.9 10.6 98.7 7.3 6.1 6.8 114.1 24.2 3.0 9.0 28.4 6.3 676.0 326.4 0.7 61.6 1585.7 21.8 57.8 431.3 2207.8 6.1 22.1 673.7 91.4 7.5 2.6 38.5 11.7 0.9 1386.6 305.7 6.3 0.1 1.3 5.9 1.0 0.6 0.2 3.2 91.5 34.9 48.0 64.6 27.9 0.0 0.4 2.7 26.1 4.4 0.3 0.0 0.0 71.2 0.0 0.2 0.1 0.1 2.3 2.5 0.0 0.4 3.0 0.1 28.7 0.1 1.6 0.0 0.0 35.8 0.0 0.0 0.0 0.3 3.8 2.9 0.0 0.7 0.2 0.6 3.8 0.0 0.0 0.1 1.3 0.1 0.2 0.2 72.5 0.1 0.1 0.4 0.4 34.6 1.2 1.2 0.1 0.4 0.1 3.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.4 8.3 5.7 14.2 6.8 8.5 6.1 6.8 6.3 6.1 7.5 6.3 2.4 0.0 0.0 0.0 0.2 4.8 4.1 1.6 0.6 0.0 4.2 191.0 51.4 0.0 0.3 1.8 0.0 0.8 0.7 0.0 0.0 14.5 335.0 3.1 20.7 2.4 0.0 0.0 0.5 0.4 1.0 21.5 0.5 0.7 0.0 0.5 6.8 0.0 2.3 0.0 0.3 0.0 0.0 0.0 9.4 554.6 8.4 0.9 3.6 2.8 0.6 0.5 0.0 0.0 0.1 0.9 0.0 221.2 0.0 4.0 0.0 0.4 0.4 0.0 39.5 1.1 180.9 8.3 19.5 0.4 7.1 0.7 1.1 0.7 0.0 1.1 CNN3 ENSG00000117519 "Calponin 3" Q15417 1 94896949-94927223 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "glioma: 315.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 10.5;naive CD4 T-cell: 11.6" "Group enriched" "Detected in many" 12 "B-cells: 10.5;T-cells: 11.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009849, HPA051237" Enhanced Enhanced "Actin filaments,Cytosol" NA NA 660000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" Cytosol "CAB009849: AB_2276410, HPA051237: AB_2681399" "unprognostic (8.47e-2)" "unprognostic (5.19e-2)" "unprognostic (5.22e-2)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-2)" "unprognostic (8.87e-2)" "unprognostic (5.20e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.37e-1)" "unprognostic (3.77e-3)" "unprognostic (2.33e-2)" "unprognostic (8.71e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (1.99e-4)" 163.9 255.6 152.7 78.9 153.7 2.1 160.0 148.6 186.3 164.8 147.7 142.4 135.9 214.0 71.0 149.7 147.1 152.3 127.6 151.7 189.9 245.1 143.7 209.0 51.4 197.4 170.9 153.1 83.3 53.1 101.7 256.0 173.1 126.2 82.8 125.0 125.5 133.7 26.3 62.5 100.0 196.0 180.8 94.1 111.8 50.2 164.5 55.1 125.0 52.6 44.3 156.5 166.2 174.0 416.6 77.9 429.0 380.1 286.0 264.2 191.7 197.2 381.3 319.4 511.2 348.7 35.6 0.1 436.6 243.4 315.7 116.2 307.2 169.9 428.1 1.6 113.0 18.8 47.5 256.2 545.0 0.2 0.8 246.2 25.5 394.1 89.4 539.6 282.8 26.7 4.1 35.3 798.9 0.2 19.8 0.9 333.6 0.3 43.3 0.6 524.2 1.8 392.9 156.6 26.3 264.2 163.0 65.0 272.8 301.7 124.8 38.5 182.4 212.2 364.9 80.2 647.0 43.9 27.2 1.5 46.0 0.6 327.1 0.2 0.0 0.0 2.2 0.1 3.4 4.6 2.1 1.2 0.1 10.5 11.6 8.3 0.4 0.9 0.1 0.0 0.0 2.6 152.7 153.7 148.6 186.3 151.7 189.9 197.4 170.9 173.1 180.8 164.5 174.0 183.5 150.6 80.7 82.9 18.1 78.3 435.7 232.3 48.9 11.9 122.2 64.1 42.2 88.6 156.2 126.9 20.9 236.1 3.2 36.0 436.3 275.1 156.1 77.4 151.1 278.3 72.4 20.0 12.9 240.7 40.9 287.8 33.1 104.9 14.0 164.4 373.0 152.1 22.6 1.7 16.9 58.7 429.3 20.1 56.3 150.7 274.6 9.3 197.5 29.0 4.7 394.6 0.0 62.4 22.7 130.8 53.2 382.1 2.6 319.1 117.9 518.5 95.1 14.4 263.0 399.8 374.9 10.8 34.7 91.4 77.7 205.8 14.9 214.5 131.0 327.4 CNNM1 ACDP1 ENSG00000119946 "Cyclin and CBS domain divalent metal cation transport mediator 1" Q9NRU3 10 99329356-99394330 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;testis: 9.8" "Cell type enhanced" "Detected in many" "Early spermatids: 103.1;Excitatory neurons: 69.9;Horizontal cells: 50.5;Inhibitory neurons: 89.5;Late spermatids: 88.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.6;BJ hTERT+: 7.4;BJ hTERT+ SV40 Large T+ RasG12V: 11.3;HAP1: 8.7;OE19: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040408 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA040408: AB_10793963" "unprognostic (9.04e-4)" "unprognostic (2.93e-1)" "unprognostic (1.70e-1)" "unprognostic (7.60e-4)" "unprognostic (4.08e-3)" "unprognostic (9.51e-2)" "unprognostic (6.01e-2)" "unprognostic (2.27e-2)" "unprognostic (6.03e-2)" "unprognostic (1.94e-1)" "unprognostic (3.09e-2)" "unprognostic (2.45e-1)" "unprognostic (8.94e-2)" "unprognostic (1.50e-1)" "unprognostic (4.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.03e-1)" 0.2 1.1 9.9 0.2 9.9 0.0 0.5 5.4 16.7 1.8 0.0 0.7 0.4 0.9 1.7 0.8 1.0 0.3 0.1 7.3 7.3 1.7 0.2 0.1 0.0 3.6 2.9 2.6 1.1 0.6 3.6 0.0 3.5 1.7 0.4 5.2 0.8 0.8 0.0 1.2 0.6 0.4 2.0 0.1 0.6 9.8 4.7 0.1 0.1 0.1 0.1 1.7 1.4 10.1 0.0 19.6 0.0 0.0 0.0 0.0 0.0 2.8 7.4 6.7 11.3 0.0 4.4 0.0 0.0 1.4 0.1 1.7 8.7 0.0 4.8 0.0 0.9 1.9 2.8 3.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.4 2.7 0.3 0.0 0.9 7.7 0.8 0.0 0.0 0.0 0.9 0.0 2.2 6.1 2.0 0.4 1.0 0.5 0.0 0.0 0.0 0.6 0.1 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 9.9 5.4 16.7 7.3 7.3 3.6 2.9 3.5 2.0 4.7 10.1 0.6 0.0 0.0 4.6 0.0 2.3 3.3 0.1 5.2 25.3 0.7 2.8 1.4 0.0 0.2 1.8 14.6 0.0 0.0 0.0 0.0 0.6 103.1 0.5 1.0 0.4 0.0 0.8 69.9 1.5 0.0 1.0 0.0 0.3 0.0 0.2 1.8 0.0 0.0 50.5 89.5 0.1 0.0 0.0 0.8 88.0 2.1 0.3 1.8 4.7 0.1 1.3 0.0 10.6 2.2 2.0 0.3 2.6 0.0 5.9 0.1 0.7 0.6 3.4 0.0 2.0 0.5 1.9 1.6 1.5 1.0 0.0 0.2 1.2 0.1 2.4 CNOT2 "CDC36, NOT2, NOT2H" ENSG00000111596 "CCR4-NOT transcription complex subunit 2" Q9NZN8 12 70243002-70354993 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Developmental protein, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067711 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA067711: AB_2685893" "unprognostic (5.00e-2)" "unprognostic (2.12e-1)" "unprognostic (6.95e-2)" "unprognostic (3.60e-2)" "unprognostic (3.48e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (7.36e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (1.32e-1)" "unprognostic (9.70e-2)" "unprognostic (2.99e-2)" "prognostic unfavorable (8.63e-5)" "unprognostic (1.28e-1)" "unprognostic (5.58e-2)" "unprognostic (5.97e-2)" "unprognostic (6.23e-2)" 29.8 25.6 24.2 31.2 33.3 78.5 35.0 65.9 28.1 29.2 24.9 31.6 30.2 34.3 34.5 24.4 29.0 27.3 24.0 25.2 28.8 28.7 34.9 29.5 40.4 33.7 32.1 35.1 24.1 32.5 23.4 32.1 30.0 27.8 34.5 46.2 26.0 27.0 33.4 50.3 30.9 30.5 28.6 35.8 25.7 26.2 32.3 50.1 30.7 33.8 42.7 32.8 27.9 43.5 46.2 44.5 70.7 45.3 38.5 42.8 60.1 49.2 59.5 53.8 46.1 55.8 42.1 100.2 45.1 57.4 33.8 43.9 50.2 49.1 59.7 47.1 50.2 66.4 38.8 55.7 40.7 84.3 54.6 50.1 52.4 50.5 59.1 78.7 59.0 61.5 61.9 55.4 47.2 52.4 95.7 61.0 61.0 46.1 46.4 75.1 59.9 61.1 50.7 93.2 50.6 55.7 59.1 46.4 45.6 60.5 59.1 68.4 44.7 50.2 33.6 45.8 40.7 50.3 59.5 77.3 52.5 42.3 41.9 92.8 49.2 57.6 50.1 69.4 56.6 54.0 54.7 58.9 60.3 51.5 62.6 67.6 30.3 62.6 58.5 44.4 55.8 56.3 24.2 33.3 65.9 28.1 25.2 28.8 33.7 32.1 30.0 28.6 32.3 43.5 71.1 41.7 43.2 76.7 79.8 51.1 37.7 45.4 47.3 64.4 40.9 38.0 30.1 58.6 45.6 36.8 56.3 45.3 144.3 50.2 33.2 49.5 44.5 47.8 55.8 55.4 58.0 49.2 110.9 44.7 47.4 57.4 41.3 62.2 76.5 60.1 46.4 34.6 40.3 52.2 115.8 39.0 44.7 55.1 46.7 12.6 45.7 62.7 32.0 86.2 46.3 54.3 56.7 123.6 204.0 45.8 44.4 46.6 77.9 45.4 45.2 30.3 44.7 54.8 39.5 72.3 64.5 53.8 44.7 46.7 64.1 35.4 94.2 50.4 39.2 48.9 CNTLN "bA340N12.1, C9orf101, C9orf39, FLJ20276" ENSG00000044459 Centlein Q9NXG0 9 17134982-17503923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8;Spermatocytes: 84.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Cell line enhanced" "Detected in many" "HEL: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007201, HPA036728, HPA036729" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Centrosome "Nucleoplasm, Cytosol" "HPA007201: AB_2667775, HPA036728: AB_10670847, HPA036729: AB_10670240" "unprognostic (1.97e-2)" "unprognostic (2.81e-3)" "unprognostic (1.81e-1)" "unprognostic (2.48e-1)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (7.71e-2)" "unprognostic (1.68e-1)" "unprognostic (7.71e-3)" "unprognostic (5.07e-3)" "unprognostic (1.06e-1)" "unprognostic (6.65e-2)" "unprognostic (2.47e-1)" "unprognostic (5.38e-2)" "unprognostic (3.35e-2)" "unprognostic (1.37e-1)" "unprognostic (5.80e-2)" 4.4 2.4 2.3 2.1 2.4 7.3 3.5 7.7 2.2 5.0 3.3 4.5 1.2 7.1 2.4 2.7 4.3 4.2 2.3 1.7 2.6 2.4 10.5 2.8 2.7 2.7 3.1 8.8 1.7 4.4 2.2 3.6 3.0 2.7 2.2 2.1 1.6 3.2 1.6 1.9 2.2 4.5 2.6 3.9 1.9 5.2 2.5 2.8 3.1 2.5 1.6 3.5 3.5 2.8 8.3 5.6 12.1 6.8 5.8 13.6 0.4 9.5 6.3 7.0 9.5 0.4 2.7 6.0 1.5 6.6 7.5 0.3 14.1 3.9 10.9 0.3 4.9 35.5 11.7 2.0 6.4 4.9 7.4 8.6 2.0 5.8 5.7 6.5 10.0 2.2 1.3 1.1 11.3 0.6 4.0 7.8 9.4 1.4 10.3 5.8 11.2 3.0 4.1 2.0 7.6 7.9 11.6 0.2 3.0 4.8 2.3 12.3 7.5 9.5 3.7 10.4 8.3 4.7 6.1 0.1 4.4 6.1 4.4 0.2 1.3 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.1 0.5 3.9 0.7 0.1 0.2 2.3 2.4 7.7 2.2 1.7 2.6 2.7 3.1 3.0 2.6 2.5 2.8 32.0 6.4 17.6 59.7 1.6 8.8 13.7 6.1 13.1 12.3 3.6 5.8 13.4 7.2 3.4 9.2 0.0 2.5 1.1 2.4 5.9 10.1 16.3 23.4 30.7 24.9 2.4 17.1 20.3 12.0 5.2 29.2 4.1 17.0 7.6 42.4 20.0 38.8 18.4 20.2 37.2 5.9 4.1 40.3 11.6 8.8 45.7 24.0 8.8 91.8 31.0 21.4 1.0 70.4 29.6 4.0 0.8 30.9 1.8 3.8 5.3 8.5 6.7 8.1 13.1 34.2 21.3 84.3 48.9 5.3 5.5 1.0 1.7 31.6 5.5 6.3 CNTN4 BIG-2 ENSG00000144619 "Contactin 4" Q8IWV2 3 2098813-3057959 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 411.7;Excitatory neurons: 960.7;Inhibitory neurons: 1048.5;Oligodendrocyte precursor cells: 248.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 8.3;CACO-2: 9.0;HEK 293: 5.5;SH-SY5Y: 16.5;WM-115: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 170000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.64e-1)" "unprognostic (7.17e-3)" "unprognostic (9.85e-2)" "unprognostic (5.75e-2)" "unprognostic (9.94e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-1)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (2.60e-2)" "unprognostic (7.38e-3)" "unprognostic (2.41e-2)" "prognostic favorable (1.00e-4)" "unprognostic (1.22e-2)" "unprognostic (2.88e-2)" "unprognostic (2.10e-1)" "unprognostic (2.13e-1)" 3.4 0.5 2.2 1.1 6.4 0.0 2.5 13.5 12.3 8.7 0.0 4.6 1.8 8.3 1.9 3.1 4.2 5.1 2.5 1.8 2.7 4.2 2.9 2.4 1.1 0.5 5.4 1.0 1.6 22.6 1.9 7.9 1.2 4.3 3.3 19.8 0.9 5.6 0.7 0.7 4.1 4.5 4.2 1.0 3.6 13.4 7.7 2.2 10.3 4.0 2.6 3.6 1.7 4.0 0.0 0.0 1.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 16.5 0.0 0.0 0.1 1.2 0.1 0.2 0.0 0.0 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 6.4 13.5 12.3 1.8 2.7 0.5 5.4 1.2 4.2 7.7 4.0 0.4 9.6 3.6 26.8 0.1 0.8 1.3 0.0 1.8 96.5 2.0 1.8 1.4 7.2 5.6 0.0 0.0 0.1 0.0 1.8 0.0 4.4 411.7 0.3 9.1 1.9 7.8 0.0 960.7 0.0 0.1 18.1 0.0 0.3 0.0 6.9 0.7 0.4 0.3 101.0 1048.5 2.0 0.0 0.3 0.7 156.3 5.0 0.4 1.8 31.9 0.0 27.5 0.0 248.3 14.7 0.0 1.6 5.3 0.4 0.4 3.7 3.7 0.0 5.9 6.6 0.5 8.3 4.5 4.9 0.9 0.0 0.3 0.1 0.1 3.5 0.2 CNTNAP2 "Caspr2, KIAA0868, NRXN4" ENSG00000174469 "Contactin associated protein 2" Q9UHC6 7 146116002-148420998 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Autism, Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 20.7;retina: 14.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3383.0;Inhibitory neurons: 6845.7" "Cancer enhanced" "Detected in many" "prostate cancer: 10.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 25 "B-cells: 2.5" "Cell line enhanced" "Detected in some" "AF22: 8.0;CACO-2: 6.7;NTERA-2: 12.0;SCLC-21H: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002739 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002739: AB_1078545" "unprognostic (2.49e-2)" "unprognostic (1.49e-2)" "unprognostic (4.05e-1)" "unprognostic (3.08e-3)" "unprognostic (1.77e-1)" "unprognostic (2.29e-1)" "unprognostic (2.51e-2)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (3.67e-2)" "unprognostic (2.68e-1)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.00e-3)" 0.2 0.8 10.0 0.2 13.8 0.0 0.6 1.4 20.7 0.1 0.0 0.8 0.0 0.0 0.0 0.4 0.6 0.0 0.2 5.6 5.7 0.1 1.9 0.0 0.4 5.7 0.5 1.1 0.2 0.3 3.8 0.5 3.8 4.1 0.4 14.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.4 0.2 0.5 1.8 3.7 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 8.0 3.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.7 0.1 0.0 0.0 0.2 0.0 2.0 1.7 0.6 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.0 1.4 0.0 0.0 0.0 2.2 0.0 0.0 21.5 1.4 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.0 13.8 1.4 20.7 5.6 5.7 5.7 0.5 3.8 0.0 1.8 0.0 0.1 0.0 0.0 65.6 9.3 0.1 0.3 15.5 1.8 33.9 0.3 0.0 1.2 7.2 4.1 0.0 2.1 40.8 0.0 1.8 0.0 1.4 7.2 0.6 0.0 0.6 2.4 0.0 3383.0 0.7 6.8 1.1 0.5 0.7 0.0 0.2 0.0 8.9 3.3 1031.4 6845.7 3.9 0.0 0.6 2.0 2.7 1.2 0.4 0.0 180.8 0.2 8.2 1.0 429.3 914.7 4.1 2.1 0.0 0.3 7.4 4.7 0.5 0.9 16.7 0.0 0.0 0.9 2.4 12.0 9.1 0.0 6.3 0.0 1.2 6.8 0.2 CNTNAP3 "CASPR3, CNTNAP3A, FLJ14195, KIAA1714" ENSG00000106714 "Contactin associated protein family member 3" Q9BZ76 9 39072767-39288315 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 26.1;Excitatory neurons: 18.6;Hepatic stellate cells: 30.0;Inhibitory neurons: 103.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "neutrophil: 7.3" "Lineage enriched" "Detected in single" 74 "granulocytes: 7.3" "Cell line enhanced" "Detected in many" "A549: 18.9;AF22: 22.5;TIME: 14.5;WM-115: 37.9" HPA047731 Uncertain "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA047731: AB_2680137" "unprognostic (9.06e-3)" "unprognostic (3.07e-2)" "unprognostic (5.74e-2)" "unprognostic (7.89e-2)" "unprognostic (7.03e-2)" "unprognostic (2.33e-3)" "unprognostic (4.58e-2)" "unprognostic (1.34e-2)" "unprognostic (1.51e-1)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (3.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.15e-2)" "unprognostic (1.20e-1)" "unprognostic (1.95e-3)" "unprognostic (1.93e-3)" 2.7 0.4 4.8 0.5 7.6 1.2 3.2 0.4 2.7 1.3 2.7 4.0 0.8 0.6 0.5 7.2 2.2 1.2 4.0 5.0 3.3 1.8 0.8 1.1 0.3 0.9 5.4 0.3 0.4 0.1 1.1 1.6 0.9 1.5 1.3 2.7 3.4 1.4 0.4 7.2 1.8 2.3 0.1 2.6 0.6 1.8 1.7 2.5 1.2 0.7 0.6 1.0 2.5 2.8 1.1 18.9 22.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 0.0 1.4 4.7 1.9 4.4 0.0 0.0 1.6 0.0 5.2 0.5 0.2 0.3 0.0 0.5 4.1 0.0 1.7 9.4 8.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.9 0.2 5.7 0.0 0.6 5.4 0.4 0.8 2.1 0.7 6.7 0.0 3.7 2.4 0.0 3.2 14.5 0.0 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 37.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 4.8 7.6 0.4 2.7 5.0 3.3 0.9 5.4 0.9 0.1 1.7 2.8 8.0 3.2 1.7 26.1 0.0 6.2 4.0 1.8 18.2 1.3 0.9 3.0 3.5 4.3 1.5 1.8 2.1 0.8 0.0 0.1 0.0 0.4 1.9 1.4 0.7 7.5 3.5 0.0 18.6 0.2 2.5 1.2 0.0 0.2 0.0 0.1 30.0 1.3 0.1 0.0 103.1 0.3 0.0 1.6 0.8 0.9 0.3 0.2 0.0 13.1 0.0 10.5 0.0 3.0 13.3 0.7 0.0 0.0 1.2 1.4 0.0 1.9 4.1 0.7 0.0 0.5 0.9 1.7 8.8 10.4 7.7 0.7 0.4 0.0 0.1 2.7 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL15A1 ENSG00000204291 "Collagen type XV alpha 1 chain" P39059 9 98943179-99070792 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 229.2" "Cell type enhanced" "Detected in many" "Adipocytes: 307.0;Endothelial cells: 190.5;Fibroblasts: 202.3;Leydig cells: 326.8;Peritubular cells: 483.3;Theca cells: 333.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 26.4;BJ hTERT+: 55.6;HDLM-2: 24.5;K-562: 18.8;U-2197: 45.6;U-87 MG: 20.6;WM-115: 31.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "spinal cord: 44.3" "HPA017913, HPA017915" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 28000000 "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA017913: AB_1847099, HPA017915: AB_1847100" "unprognostic (4.30e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-2)" "unprognostic (2.09e-1)" "unprognostic (1.09e-2)" "prognostic favorable (5.47e-4)" "unprognostic (3.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-3)" "unprognostic (3.66e-3)" "unprognostic (8.98e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (3.08e-4)" 84.7 36.9 0.6 50.6 0.9 0.1 46.7 0.8 1.0 31.2 4.0 44.5 12.9 53.8 19.2 26.9 17.3 42.8 58.0 0.4 0.8 12.9 1.0 11.1 10.4 0.6 0.9 23.2 26.8 11.8 6.0 229.2 0.7 21.6 16.3 0.0 35.9 14.3 56.5 15.1 17.7 108.9 0.6 3.7 27.3 27.0 2.4 13.0 21.1 34.4 8.6 42.1 15.1 0.7 0.0 0.0 0.1 0.0 4.6 2.6 0.1 26.4 55.6 1.4 0.5 0.0 0.0 0.2 0.7 5.8 0.2 0.1 0.0 0.0 0.2 24.5 0.0 0.3 12.9 0.0 1.1 0.4 2.5 7.6 0.0 6.0 0.2 0.0 0.0 0.0 18.8 0.0 2.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 14.7 0.2 0.0 0.0 0.1 0.1 0.8 3.9 7.4 0.3 0.2 0.6 0.0 0.1 0.6 45.6 0.5 0.2 0.0 0.0 20.6 0.2 31.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.8 1.0 0.4 0.8 0.6 0.9 0.7 0.6 2.4 0.7 307.0 0.0 0.0 0.7 0.5 19.5 0.1 0.0 5.2 0.0 2.6 4.1 8.1 0.0 0.0 0.0 0.0 3.8 1.8 0.0 0.0 2.4 5.7 3.9 103.4 190.5 0.0 0.0 0.4 0.8 3.7 202.3 0.5 2.2 0.0 0.3 0.0 0.0 7.6 0.0 2.9 0.0 0.0 0.3 27.2 22.5 326.8 3.1 17.8 46.9 0.6 0.0 1.0 1.0 0.3 0.6 0.0 483.3 0.3 1.2 0.0 0.5 0.0 0.0 13.1 107.8 52.8 1.9 1.2 1.3 16.3 7.7 2.1 333.4 0.0 0.7 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 479.6;Sertoli cells: 223.5;Smooth muscle cells: 268.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 139.0;EFO-21: 309.4;NTERA-2: 170.6;RPTEC TERT1: 131.6;TIME: 186.0" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA 290000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" 136.4 87.6 14.5 33.9 22.3 15.9 97.1 26.4 21.8 229.4 34.4 91.2 30.4 135.6 35.4 50.1 118.3 28.9 122.2 15.7 18.1 218.2 561.9 83.2 19.8 43.7 28.6 257.3 102.3 7.9 106.5 40.7 39.1 91.0 5.5 5.4 35.8 46.8 26.5 77.8 65.7 28.5 26.6 86.8 44.5 30.0 27.0 9.0 101.1 7.4 7.2 109.8 112.2 45.4 10.5 84.0 20.6 18.0 38.6 31.9 3.3 82.0 139.0 39.1 10.5 48.8 28.9 1.5 309.4 82.8 21.6 37.9 4.6 5.0 7.4 0.7 20.0 47.9 1.4 69.6 37.3 0.7 4.4 37.6 3.3 3.8 4.5 8.5 121.3 0.5 49.6 0.3 14.4 16.7 0.8 3.2 170.6 3.2 30.7 0.7 12.6 4.0 131.6 1.3 22.8 16.3 7.6 7.8 26.6 73.0 7.5 9.9 186.0 0.5 11.4 0.4 17.7 0.4 0.8 1.5 0.1 1.7 32.7 0.8 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.2 3.2 0.0 0.0 0.1 0.0 0.1 14.5 22.3 26.4 21.8 15.7 18.1 43.7 28.6 39.1 26.6 27.0 45.4 156.9 0.0 4.1 6.5 3.9 67.7 15.5 19.0 67.7 13.5 9.3 32.1 15.7 61.5 5.0 112.2 4.2 1.9 3.4 0.1 9.8 117.5 1.5 58.3 99.5 91.2 0.0 33.0 4.9 5.8 1.1 101.1 3.6 144.2 57.8 6.6 75.0 479.6 2.4 0.0 15.8 0.1 4.1 12.1 32.5 6.7 79.9 6.5 49.8 82.4 3.2 141.9 7.2 4.0 28.0 9.9 0.0 126.0 4.6 14.0 0.0 72.9 0.7 6.3 223.5 138.2 268.6 4.1 6.0 7.9 28.6 2.5 15.3 47.5 0.4 2.6 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1831.7;gallbladder: 1378.0;smooth muscle: 1416.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 774.5;Fibroblasts: 2148.2;Glandular and luminal cells: 592.2;Leydig cells: 991.9;Peritubular cells: 501.0;Smooth muscle cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3899.2;ASC TERT1: 4637.0;BJ: 3995.6;BJ hTERT+: 2901.2;fHDF/TERT166: 13615.1;HSkMC: 4058.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 133.7" "CAB032650, HPA059738" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 27000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA059738: AB_2684116" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" 514.8 52.4 6.8 266.2 9.3 2.0 314.5 7.1 17.4 1831.7 18.1 175.7 61.1 411.2 61.6 263.2 206.6 1378.0 275.4 6.0 6.8 40.8 27.4 229.5 91.6 8.7 6.7 297.2 57.1 32.5 33.5 624.6 7.9 196.2 141.8 1.6 60.2 232.3 51.6 424.6 103.2 1416.9 8.8 69.3 89.1 136.6 15.6 32.8 86.4 102.1 60.1 805.6 295.2 8.2 0.1 0.0 22.8 1488.5 3899.2 4637.0 1.3 3995.6 2901.2 642.6 850.5 0.0 2.8 0.3 2.7 13615.1 0.0 0.6 2.2 1.5 160.9 0.1 0.2 0.1 0.0 0.0 1018.6 1.1 0.5 4058.4 0.1 507.9 2.4 0.3 0.5 0.0 0.3 0.3 551.0 0.0 0.6 1.5 2.5 0.0 6.3 0.5 0.8 0.8 0.1 0.0 12.9 1.4 0.3 1.0 0.1 296.0 2.1 0.1 15.9 1626.3 0.8 1022.7 115.5 1.2 0.1 0.4 408.6 0.5 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 9.3 7.1 17.4 6.0 6.8 8.7 6.7 7.9 8.8 15.6 8.2 112.9 3.2 12.9 1.0 0.8 223.1 0.7 9.3 4.6 0.2 7.2 8.6 21.7 0.0 3.3 1.8 0.0 31.5 2.5 0.0 0.0 3.0 8.4 183.2 774.5 57.2 0.0 0.0 0.0 0.2 31.7 2148.2 26.5 592.2 10.1 16.4 258.8 1.9 116.9 0.0 0.1 0.0 0.0 1.0 394.5 45.1 991.9 16.7 238.3 97.4 2.6 3.2 0.0 0.0 0.2 5.2 0.0 501.0 4.5 1.0 0.0 0.5 0.8 0.4 302.4 249.9 770.7 9.9 4.5 6.2 187.4 70.7 30.6 214.8 0.0 0.8 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 COL6A6 ENSG00000206384 "Collagen type VI alpha 6 chain" A6NMZ7 3 130560334-130678155 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "parathyroid gland: 97.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.6;Fibroblasts: 20.6;Inhibitory neurons: 5.3;Oligodendrocytes: 4.6;Skeletal myocytes: 3.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SuSa: 1.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "spinal cord: 10.0" HPA045239 Uncertain "Secreted to extracellular matrix" NA NA 700000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA045239: AB_2679268" "unprognostic (4.86e-3)" "unprognostic (2.16e-2)" "unprognostic (9.91e-2)" "unprognostic (2.08e-4)" "unprognostic (2.79e-1)" "unprognostic (1.11e-5)" "unprognostic (3.74e-3)" "unprognostic (5.59e-2)" "unprognostic (1.42e-1)" "unprognostic (3.50e-2)" "unprognostic (8.90e-2)" "unprognostic (2.70e-1)" "unprognostic (2.96e-4)" "unprognostic (5.82e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (1.07e-1)" 1.8 0.0 0.0 0.0 0.2 0.2 2.5 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.3 0.9 0.3 0.1 3.3 0.0 0.0 0.0 0.8 7.3 0.0 0.0 0.0 0.2 0.0 97.8 3.6 0.7 0.0 0.0 0.0 0.3 1.5 0.0 0.1 0.4 0.0 0.5 0.0 1.2 0.1 0.4 0.1 1.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 1.1 1.3 0.0 0.9 0.0 0.0 0.0 1.1 0.2 0.4 2.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 2.9 0.1 0.0 0.0 4.6 0.0 0.0 20.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.3 0.0 0.0 0.0 1.5 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 3.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 3.3 0.8 0.0 0.4 0.0 0.9 0.1 0.2 0.0 0.0 0.0 COL9A2 "EDM2, MED" ENSG00000049089 "Collagen type IX alpha 2 chain" Q14055 1 40300489-40317813 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.2;pituitary gland: 108.1" "Cell type enhanced" "Detected in many" "Muller glia cells: 295.4;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 128.1" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 3.2;myeloid DC: 1.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.2;granulocytes: 3.2" "Group enriched" "Detected in many" 4 "HDLM-2: 98.6;Hep G2: 27.6;HMC-1: 90.3;THP-1: 105.0" "Low region specificity" "Detected in all" "HPA056316, HPA075286" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 510000 "Cluster 52: Eosinophils - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles Nucleoplasm "HPA056316: AB_2683099, HPA075286: AB_2732288" "unprognostic (1.42e-2)" "unprognostic (3.54e-2)" "unprognostic (8.94e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.46e-2)" "unprognostic (1.83e-3)" "unprognostic (2.06e-2)" "unprognostic (9.00e-3)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (2.26e-1)" "unprognostic (1.16e-3)" "unprognostic (4.28e-2)" "unprognostic (2.56e-1)" "unprognostic (5.89e-2)" "unprognostic (1.71e-2)" 2.2 3.4 42.6 3.7 71.5 10.9 5.9 58.9 51.1 12.1 21.6 6.5 5.8 5.0 1.7 1.6 11.4 8.5 2.2 38.2 49.7 24.6 0.9 4.3 5.9 65.9 74.1 1.3 2.3 21.0 108.1 1.1 66.2 13.7 3.1 23.1 16.3 24.2 0.2 4.6 10.4 1.4 52.0 9.8 16.5 2.6 58.6 1.8 12.2 0.3 3.1 12.1 2.0 86.2 12.0 0.3 1.8 0.8 2.6 1.3 7.8 0.0 0.0 0.6 1.3 0.4 6.8 3.4 10.0 0.3 0.0 2.0 0.1 0.0 0.3 98.6 1.4 2.0 0.8 27.6 1.5 0.9 90.3 4.8 0.0 0.1 0.0 0.7 0.0 1.5 0.1 19.8 0.0 2.7 1.2 2.1 2.2 0.0 1.2 2.3 0.0 6.9 0.0 14.3 1.4 2.3 0.1 11.8 1.3 6.6 15.0 105.0 0.1 0.0 11.6 0.2 0.4 1.4 0.2 3.4 1.0 12.3 0.6 0.0 0.1 3.2 0.0 0.2 0.0 0.2 0.1 0.0 1.2 0.2 0.0 0.0 0.5 0.2 0.3 0.1 0.1 0.0 42.6 71.5 58.9 51.1 38.2 49.7 65.9 74.1 66.2 52.0 58.6 86.2 0.5 0.0 3.3 26.1 10.8 1.0 3.0 8.5 0.0 2.0 7.1 9.7 1.0 7.2 10.0 25.8 0.0 3.2 2.5 7.2 0.0 11.7 0.2 13.6 0.9 0.6 12.7 0.4 0.3 0.8 0.6 2.1 26.0 20.0 26.1 1.6 1.1 0.0 3.4 0.0 0.3 6.6 2.0 0.3 22.4 0.9 2.1 6.4 1.8 3.7 22.1 295.4 1.0 62.4 128.1 4.9 9.6 0.0 4.0 6.1 5.0 0.3 12.9 10.9 0.0 1.3 1.8 3.4 6.2 0.2 0.6 1.4 2.7 1.8 13.4 13.4 COL9A3 "DJ885L7.4.1, EDM3, FLJ90759, IDD, MED" ENSG00000092758 "Collagen type IX alpha 3 chain" Q14050 20 62816244-62841159 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.7;choroid plexus: 34.4;thyroid gland: 25.4" "Cell type enhanced" "Detected in many" "Early spermatids: 116.6;Late spermatids: 401.9;Muller glia cells: 95.8;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 68.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 143.4;Hep G2: 59.6;SK-MEL-30: 51.1;WM-115: 57.8" "Low region specificity" "Detected in all" "HPA040125, HPA058323" Supported Approved "Nucleoplasm,Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Intermediate filaments" "HPA040125: AB_10805604, HPA058323: AB_2683679" "unprognostic (1.14e-3)" "unprognostic (2.14e-2)" "unprognostic (3.93e-1)" "unprognostic (1.21e-3)" "unprognostic (4.25e-2)" "unprognostic (2.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.24e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.67e-1)" 1.6 1.5 17.5 0.7 35.7 0.0 2.8 22.4 21.6 3.3 34.4 12.1 0.7 1.2 0.2 1.3 1.7 0.1 6.3 13.0 16.5 2.9 0.6 0.4 0.2 37.4 31.0 1.7 7.6 0.1 14.0 0.5 24.2 3.2 0.1 1.6 23.6 1.2 0.5 1.9 3.1 0.1 20.5 0.3 2.7 20.7 31.6 0.1 25.4 0.0 0.0 2.8 3.8 39.7 0.2 0.3 0.3 0.2 0.0 0.8 143.4 0.1 0.0 0.1 0.0 1.6 0.2 0.0 13.1 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.9 0.0 8.2 59.6 0.3 0.0 0.5 2.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.3 0.0 0.0 1.0 0.7 6.4 8.2 0.0 2.5 0.0 1.8 0.0 0.1 0.0 1.5 0.2 0.1 51.1 4.6 0.2 5.4 0.0 0.0 0.7 0.1 1.0 0.2 0.1 0.0 0.2 0.0 57.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 35.7 22.4 21.6 13.0 16.5 37.4 31.0 24.2 20.5 31.6 39.7 1.6 3.2 0.0 1.0 26.1 3.2 2.2 1.2 1.8 0.9 2.1 2.5 1.6 0.0 0.2 5.5 10.4 5.1 0.4 0.7 1.9 3.6 116.6 2.7 0.4 3.7 4.2 1.3 2.5 0.0 46.4 15.3 6.1 0.7 0.0 0.6 2.5 6.8 2.2 0.0 2.0 3.3 0.0 2.2 0.9 401.9 4.1 1.7 3.6 0.0 0.5 95.8 0.0 84.9 68.9 0.1 7.3 1.5 44.0 1.2 2.3 23.7 2.5 3.7 0.0 0.8 1.0 2.9 7.8 0.9 7.0 4.0 1.4 3.7 2.0 1.0 COP1 "CFAP78, FAP78, FLJ10416, RFWD2, RNF200" ENSG00000143207 "COP1 E3 ubiquitin ligase" Q8NHY2 1 175944831-176207286 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.1;Extravillous trophoblasts: 33.5;Syncytiotrophoblasts: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.99e-1)" "unprognostic (3.76e-2)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (2.95e-2)" "unprognostic (4.33e-1)" "unprognostic (2.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.52e-2)" "unprognostic (9.24e-2)" "unprognostic (1.67e-1)" "unprognostic (1.33e-2)" "unprognostic (6.68e-2)" "unprognostic (7.01e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-1)" 14.2 9.5 5.9 12.0 7.1 16.8 12.7 11.4 9.1 12.1 8.4 18.1 13.8 11.8 9.8 14.2 9.4 9.5 9.8 8.5 5.9 12.4 16.6 12.5 15.7 4.6 5.0 8.7 13.2 10.5 8.0 11.2 5.0 10.1 16.7 8.6 13.1 8.5 13.6 17.5 13.9 11.0 5.7 16.7 13.7 15.6 6.1 14.9 10.6 7.4 16.8 14.7 11.9 8.8 35.3 17.5 22.1 13.8 23.0 22.6 56.1 21.7 22.0 17.7 18.6 30.0 28.1 59.4 25.8 20.9 18.9 32.3 16.9 27.0 17.7 23.7 17.0 22.6 19.4 28.0 18.9 49.2 33.0 16.8 28.9 17.6 19.8 17.9 26.6 21.7 43.9 24.9 24.8 42.5 27.0 28.2 47.4 55.8 2.0 26.1 20.4 40.2 26.8 93.7 22.6 41.6 27.8 44.9 35.9 37.4 32.1 69.1 40.4 19.4 16.1 28.3 23.4 35.3 62.7 49.8 19.1 26.7 26.9 8.5 3.0 12.0 1.9 3.7 1.4 1.7 2.0 1.4 2.1 1.5 2.7 2.0 14.1 0.6 3.4 1.1 1.7 1.0 5.9 7.1 11.4 9.1 8.5 5.9 4.6 5.0 5.0 5.7 6.1 8.8 15.8 22.4 14.5 0.0 4.4 0.0 0.0 0.0 0.0 0.0 15.4 10.9 0.0 0.0 3.1 9.2 0.0 28.1 12.2 0.0 21.5 14.8 0.0 17.9 14.6 7.2 0.0 0.0 0.0 22.7 33.5 7.4 0.0 20.1 7.6 18.1 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 21.8 0.0 0.0 3.1 0.0 0.0 22.1 4.4 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 31.3 6.7 13.8 0.0 0.0 COPZ2 MGC23008 ENSG00000005243 "COPI coat complex subunit zeta 2" Q9P299 17 48026167-48038030 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 49.8;Endometrial stromal cells: 63.8;Fibroblasts: 77.7;Leydig cells: 50.4;Smooth muscle cells: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 167.4;ASC TERT1: 185.6;BJ: 127.1;BJ hTERT+: 133.1;fHDF/TERT166: 271.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055999 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA055999: AB_2683003" "unprognostic (2.66e-1)" "unprognostic (9.32e-2)" "unprognostic (2.18e-2)" "unprognostic (1.46e-1)" "unprognostic (6.28e-2)" "unprognostic (1.12e-1)" "unprognostic (2.77e-2)" "unprognostic (1.59e-1)" "unprognostic (9.34e-2)" "unprognostic (2.49e-1)" "unprognostic (7.02e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (3.45e-9)" "unprognostic (7.42e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (2.89e-6)" "prognostic unfavorable (4.66e-4)" 71.7 28.6 11.8 11.7 12.6 1.0 46.4 13.0 19.1 41.8 22.8 57.0 6.2 38.3 21.4 15.9 32.6 22.9 57.1 12.4 16.4 19.2 33.2 22.1 5.8 15.3 12.5 13.6 19.7 24.3 14.8 22.5 15.1 34.2 14.7 5.1 23.4 36.8 90.8 35.3 18.2 45.6 14.0 11.7 27.1 11.6 13.1 4.9 32.1 48.6 6.9 37.3 33.1 15.7 38.7 7.5 4.1 0.0 167.4 185.6 0.0 127.1 133.1 35.0 38.6 0.0 4.4 0.0 28.3 271.6 0.0 39.5 0.0 0.5 34.9 1.7 0.1 13.6 21.3 0.1 68.4 0.0 0.8 111.7 16.0 26.2 3.5 41.1 5.3 0.3 0.1 0.8 86.9 18.1 0.4 0.0 0.2 2.6 2.5 0.0 0.0 6.1 2.4 0.0 0.2 5.7 24.6 0.0 28.3 1.0 6.0 4.2 34.4 91.5 14.5 72.9 0.5 91.6 11.1 1.3 99.3 0.0 13.1 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.1 11.8 12.6 13.0 19.1 12.4 16.4 15.3 12.5 15.1 14.0 13.1 15.7 31.6 9.6 2.2 8.1 2.6 49.8 16.7 9.4 9.1 1.2 7.3 30.1 37.1 0.0 1.4 7.3 0.0 1.0 7.5 0.4 11.7 1.0 7.0 2.1 63.8 15.6 0.0 0.0 1.4 5.1 1.2 77.7 0.0 1.5 1.3 2.7 16.4 39.0 6.9 0.0 1.7 2.3 2.0 4.4 28.4 21.1 50.4 3.4 28.4 7.5 0.8 34.8 4.1 2.5 7.6 2.5 0.0 41.8 3.5 6.0 0.1 19.1 0.6 1.3 6.6 21.6 49.2 14.1 3.7 3.1 26.0 2.3 3.7 8.5 0.4 11.7 COQ2 "CL640, FLJ26072" ENSG00000173085 "Coenzyme Q2, polyprenyltransferase" Q96H96 4 83261536-83284914 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Disease variant, Neurodegeneration, Parkinsonism, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 37.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 50.7;Kupffer cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056599, HPA068727" Approved Approved Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056599: AB_2683184, HPA068727: AB_2686022" "unprognostic (8.26e-2)" "unprognostic (7.40e-3)" "unprognostic (3.95e-3)" "unprognostic (1.55e-1)" "unprognostic (9.22e-2)" "unprognostic (5.59e-2)" "unprognostic (1.26e-2)" "unprognostic (1.52e-1)" "unprognostic (4.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.56e-2)" "unprognostic (3.73e-1)" "unprognostic (1.40e-1)" "unprognostic (7.82e-2)" "unprognostic (2.46e-1)" 6.0 17.0 2.8 8.0 3.2 11.8 5.8 3.5 3.3 7.9 3.6 14.2 9.5 6.3 7.5 10.4 4.4 4.3 15.0 3.0 3.5 5.6 13.6 7.9 6.4 3.6 3.5 6.5 6.5 6.0 4.0 8.4 3.8 6.6 14.2 4.0 7.8 5.0 29.1 10.8 9.1 6.9 4.1 10.1 5.5 3.5 3.9 3.6 5.7 37.5 7.1 7.9 6.5 4.9 26.1 14.7 14.1 27.4 10.5 11.9 9.7 16.1 27.0 29.7 34.4 10.5 38.7 17.2 11.7 28.4 24.6 18.6 23.9 26.0 38.7 17.2 14.8 15.3 22.3 15.4 11.7 31.3 73.5 15.9 16.3 14.2 24.8 8.9 30.7 9.7 10.0 21.4 29.3 27.4 8.6 21.7 10.9 30.6 19.9 14.1 11.4 22.1 45.4 13.8 10.3 6.3 19.0 24.5 9.2 6.7 15.4 18.8 21.0 14.6 14.6 11.1 23.4 5.7 5.2 10.2 29.5 36.8 20.2 2.1 28.8 4.0 2.7 26.8 1.9 6.2 3.0 2.5 21.1 6.9 2.1 3.2 9.8 6.7 33.5 11.2 4.1 13.6 2.8 3.2 3.5 3.3 3.0 3.5 3.6 3.5 3.8 4.1 3.9 4.9 5.4 0.0 4.2 15.7 11.5 6.6 12.4 9.8 4.6 5.9 6.3 5.6 19.5 2.8 10.7 9.2 0.0 25.4 7.1 14.0 31.3 6.7 0.8 7.6 19.5 6.1 4.8 14.1 12.8 10.8 30.0 9.0 6.6 9.2 0.0 17.2 9.3 15.0 50.7 1.7 20.1 15.3 8.2 53.2 7.9 0.8 3.7 25.2 7.2 33.7 21.8 12.6 6.2 25.6 15.6 5.4 15.4 4.9 4.3 12.6 11.0 9.9 6.2 4.8 0.0 7.3 9.7 18.1 19.7 16.7 12.6 12.4 9.6 35.5 26.7 12.9 CORO2A "IR10, WDR2" ENSG00000106789 "Coronin 2A" Q92828 9 98120975-98192637 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.2;Proximal enterocytes: 93.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 11.4;monocytes: 7.8;T-cells: 11.9" "Cell line enhanced" "Detected in many" "BEWO: 66.6;OE19: 56.4;SK-BR-3: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041161, HPA041302" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA041161: AB_10795537, HPA041302: AB_10794195" "unprognostic (4.49e-3)" "unprognostic (3.44e-2)" "unprognostic (3.14e-1)" "unprognostic (1.78e-1)" "unprognostic (3.39e-3)" "unprognostic (1.64e-1)" "unprognostic (3.73e-2)" "unprognostic (5.73e-2)" "unprognostic (2.79e-1)" "unprognostic (1.52e-1)" "unprognostic (4.50e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" "unprognostic (6.40e-3)" 1.9 1.7 1.9 4.9 1.5 14.8 4.7 4.9 3.2 6.1 0.0 17.5 34.3 1.6 0.7 15.2 4.7 18.2 0.3 1.2 2.9 1.1 3.3 7.4 2.9 3.7 3.4 0.3 0.4 2.5 4.0 2.1 4.9 14.3 12.9 1.2 6.1 1.4 0.3 9.3 35.1 2.2 0.8 3.0 11.1 9.2 4.5 5.7 1.2 0.3 5.9 12.8 7.7 1.8 8.4 2.9 0.6 2.0 1.2 1.3 66.6 0.6 0.7 2.1 3.2 19.1 1.4 0.1 9.4 1.2 3.2 23.1 7.7 12.7 1.3 6.9 1.8 0.2 11.6 17.1 2.7 7.9 0.7 0.4 15.4 1.0 18.6 0.7 0.7 10.0 6.8 3.8 0.3 6.3 1.5 7.8 8.6 56.4 2.2 6.1 0.1 0.2 1.3 23.5 1.7 2.4 4.4 45.3 1.6 15.0 5.3 12.8 0.6 0.2 9.7 0.2 2.4 0.7 4.0 0.7 0.5 2.5 2.8 11.2 1.4 11.4 2.4 2.9 5.2 0.6 3.9 3.7 0.5 0.5 2.5 3.3 1.0 1.7 7.8 0.7 11.9 1.5 1.9 1.5 4.9 3.2 1.2 2.9 3.7 3.4 4.9 0.8 4.5 1.8 2.8 12.8 27.8 0.7 3.1 6.6 18.9 47.2 14.8 2.1 8.5 4.3 1.9 28.6 46.4 0.0 4.2 10.5 2.1 76.2 0.0 4.5 2.6 15.6 11.6 6.0 7.2 0.8 11.6 5.1 42.2 2.2 36.2 19.9 0.0 38.1 0.7 3.8 6.0 1.7 10.5 15.7 20.3 12.0 2.6 3.9 0.0 10.6 0.0 1.0 1.8 0.7 2.1 0.5 0.8 22.6 19.7 0.4 1.4 15.7 93.0 1.7 35.8 1.7 0.0 1.5 3.7 0.5 3.3 29.4 9.9 15.9 10.7 0.2 36.3 30.4 CPLX1 CPX-I ENSG00000168993 "Complexin 1" O14810 4 784957-826129 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 273.5" "Cell type enhanced" "Detected in many" "Adipocytes: 45.5;Bipolar cells: 33.4;Endothelial cells: 29.6;Excitatory neurons: 44.2;Inhibitory neurons: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 84.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA071191: , HPA074390: " "unprognostic (9.21e-3)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.45e-2)" "unprognostic (4.68e-2)" "unprognostic (1.16e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" "unprognostic (2.26e-2)" "unprognostic (9.52e-3)" "unprognostic (2.01e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.10e-3)" "unprognostic (3.32e-1)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" "unprognostic (1.34e-1)" "unprognostic (7.77e-2)" 17.2 13.4 26.1 1.2 43.0 0.1 18.2 59.7 273.5 16.9 0.0 5.0 1.0 10.8 0.1 5.7 16.4 0.4 11.5 18.5 72.8 10.9 8.3 9.4 0.8 135.5 25.1 9.4 3.2 1.4 12.8 0.3 128.2 13.8 0.2 5.7 9.6 0.7 4.1 3.4 5.1 0.4 13.9 27.2 4.9 8.6 124.2 3.6 7.5 0.2 0.2 8.3 12.9 89.9 5.7 0.5 0.1 0.8 0.0 0.0 0.3 0.2 0.0 0.0 0.0 16.3 1.7 4.2 1.9 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.8 0.4 0.0 1.8 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.3 2.0 0.3 0.0 2.5 2.3 0.0 2.6 4.4 2.6 0.1 0.0 1.6 0.0 0.4 84.3 11.8 0.4 5.5 0.0 0.2 8.5 0.3 0.1 0.0 0.5 0.1 0.1 0.2 4.7 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 26.1 43.0 59.7 273.5 18.5 72.8 135.5 25.1 128.2 13.9 124.2 89.9 45.5 0.0 0.0 5.9 0.4 1.0 3.2 0.4 1.8 33.4 7.8 8.1 3.6 0.0 1.9 0.0 4.2 0.1 2.8 2.5 1.9 1.2 1.4 1.1 5.4 29.6 21.5 0.0 44.2 0.8 3.2 1.8 2.6 1.4 0.0 0.3 14.3 4.8 0.2 18.5 90.7 2.1 0.0 0.3 1.9 2.3 1.8 0.5 1.8 8.4 0.0 16.8 0.0 8.0 4.7 0.8 5.2 0.0 0.6 2.6 0.3 1.2 0.0 21.7 0.0 0.4 2.3 4.3 9.8 0.2 1.1 1.0 1.6 0.8 2.7 1.3 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 219.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 306.1;Kupffer cells: 290.3;Langerhans cells: 531.0;Macrophages: 266.2;monocytes: 176.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1136.9;intermediate monocyte: 953.5;myeloid DC: 1319.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1319.5;monocytes: 1136.9" "Cell line enhanced" "Detected in many" "BEWO: 190.8;RPTEC TERT1: 801.1;U-266/84: 205.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 760000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" 44.0 23.5 7.5 66.3 8.7 59.8 24.9 48.9 12.0 28.5 39.6 28.9 32.8 17.1 34.6 25.4 19.8 42.1 79.3 6.8 9.9 96.7 52.9 57.6 92.9 15.2 11.4 18.1 7.9 5.4 10.1 84.9 15.4 17.9 25.7 0.9 5.3 21.3 12.5 19.3 46.5 34.1 11.8 219.0 15.5 34.4 8.8 66.7 128.4 8.3 35.8 50.6 15.8 23.4 1.5 0.2 20.3 0.1 0.1 0.0 190.8 0.0 0.0 1.9 0.4 59.8 0.1 0.0 90.3 0.8 94.4 3.2 51.8 4.2 0.6 0.4 47.9 67.0 1.2 144.5 0.0 0.0 0.3 0.3 5.9 0.7 1.6 0.0 0.6 27.5 45.5 0.1 1.6 0.0 63.4 0.4 31.6 0.1 16.0 0.3 0.0 0.6 801.1 22.8 11.9 9.4 53.6 125.5 101.7 97.0 15.1 49.6 0.0 0.4 0.8 0.5 12.0 17.5 205.5 1.0 0.2 25.0 20.8 19.5 1136.9 5.7 2.6 953.5 3.4 1.8 1.3 1.9 1319.5 1.2 1.2 1.2 23.4 5.8 327.8 34.8 1.5 1142.7 7.5 8.7 48.9 12.0 6.8 9.9 15.2 11.4 15.4 11.8 8.8 23.4 12.3 6.4 16.0 3.3 7.2 12.5 1.3 0.7 5.7 0.0 2.6 3.4 69.1 10.0 2.5 71.7 0.0 138.0 2.1 0.2 35.2 0.5 24.7 3.7 0.3 21.1 1.8 34.1 3.7 15.6 118.3 29.4 1.1 0.6 5.1 2.3 6.8 1.1 306.1 0.0 1.7 1.2 0.0 290.3 531.0 7.6 9.3 266.2 10.6 45.9 176.8 0.2 2.1 2.0 1.3 0.8 0.4 3.0 2.9 0.5 0.4 30.6 1.5 0.4 0.0 31.0 3.0 27.1 92.8 27.2 8.8 118.5 3.3 3.6 1.2 0.9 CRACR2A "EFCAB4B, MGC4266" ENSG00000130038 "Calcium release activated channel regulator 2A" Q9BSW2 12 3606633-3764819 "Predicted intracellular proteins" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.0;intestine: 13.5;salivary gland: 38.6" "Cell type enhanced" "Detected in many" "dendritic cells: 14.9;Intestinal goblet cells: 46.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "basophil: 16.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 29.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA038686 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA038686: AB_10671748" "unprognostic (6.78e-2)" "unprognostic (3.82e-2)" "unprognostic (3.96e-2)" "unprognostic (9.15e-2)" "unprognostic (1.40e-3)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.71e-2)" "unprognostic (2.17e-2)" "unprognostic (5.47e-2)" "unprognostic (5.11e-2)" "prognostic favorable (2.85e-6)" "unprognostic (4.94e-3)" "unprognostic (2.01e-2)" "unprognostic (3.43e-2)" "unprognostic (1.21e-1)" "unprognostic (5.04e-2)" 1.4 0.2 0.2 3.6 1.0 17.0 5.0 0.1 0.3 2.1 0.7 9.1 4.5 0.7 0.1 0.5 0.5 1.7 1.9 0.2 0.1 0.2 1.0 1.3 4.0 0.6 0.3 1.1 3.3 0.1 0.2 0.2 0.4 4.2 13.5 0.1 38.6 0.7 0.3 1.8 8.4 1.1 0.3 2.9 3.5 1.1 0.6 6.1 0.6 0.4 3.6 2.8 0.3 0.4 13.2 4.4 0.9 0.2 1.7 5.1 10.1 1.4 1.2 3.7 5.1 8.9 2.6 19.5 0.5 5.1 0.2 0.0 14.7 0.0 5.2 29.4 3.3 17.1 0.0 0.0 2.9 23.9 0.4 3.9 1.5 11.4 0.1 0.0 10.7 18.4 12.0 8.4 4.8 10.7 22.0 11.6 5.3 24.6 0.0 11.7 11.9 3.8 0.0 16.6 9.5 2.2 3.0 3.1 0.1 0.9 0.6 13.4 15.6 0.0 15.3 12.6 0.0 0.1 0.0 24.9 0.0 11.1 0.0 16.9 1.0 2.5 5.0 1.0 5.0 2.6 2.5 4.0 0.8 0.9 1.4 2.5 1.1 3.5 0.2 0.3 1.0 1.7 0.2 1.0 0.1 0.3 0.2 0.1 0.6 0.3 0.4 0.3 0.6 0.4 0.9 0.0 0.6 1.0 6.1 0.0 1.3 0.0 0.6 1.1 12.8 9.4 3.8 0.0 3.1 0.0 2.1 0.1 14.9 4.3 0.0 1.6 1.5 0.4 5.5 1.2 0.0 3.0 3.4 2.9 0.6 3.1 6.1 0.3 0.0 13.2 2.2 0.5 2.0 0.0 5.5 46.0 0.0 2.5 0.0 2.9 1.8 3.1 0.0 4.7 3.2 0.1 8.2 0.0 0.6 1.9 5.3 4.5 8.6 4.7 3.2 0.2 2.9 0.2 0.0 4.2 2.0 1.2 2.9 0.2 0.0 0.0 12.1 2.6 8.1 1.8 CRACR2B "EFCAB4A, MGC45840" ENSG00000177685 "Calcium release activated channel regulator 2B" Q8N4Y2 11 826144-831991 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 208.7;salivary gland: 223.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 180.4;Breast myoepithelial cells: 116.3;Gastric mucus-secreting cells: 178.9;Hepatic stellate cells: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 3.4;eosinophil: 3.7;memory B-cell: 3.9;naive B-cell: 3.0;NK-cell: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.9;granulocytes: 3.7;NK-cells: 1.7" "Cell line enhanced" "Detected in many" "NB-4: 35.2;OE19: 29.6;SK-BR-3: 111.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046217 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA046217: AB_10960833" "unprognostic (8.87e-2)" "unprognostic (4.89e-2)" "prognostic unfavorable (1.81e-5)" "unprognostic (4.47e-3)" "unprognostic (8.20e-3)" "unprognostic (5.27e-3)" "unprognostic (7.31e-2)" "unprognostic (1.90e-2)" "unprognostic (1.63e-1)" "unprognostic (5.61e-3)" "unprognostic (3.49e-3)" "unprognostic (9.25e-3)" "unprognostic (5.28e-2)" "unprognostic (4.29e-3)" "unprognostic (3.03e-1)" "unprognostic (3.65e-1)" "unprognostic (5.15e-3)" 11.9 8.4 1.5 3.3 1.6 13.3 65.8 3.1 2.1 8.3 3.5 43.6 22.4 4.6 1.0 6.7 6.4 6.8 22.4 1.3 1.5 27.0 3.4 14.9 2.4 1.8 1.5 1.3 208.7 6.8 23.3 2.7 1.8 44.9 13.6 1.0 223.6 5.2 4.3 21.9 28.5 1.2 1.1 13.9 81.0 2.4 1.9 0.6 6.4 1.7 2.0 19.6 3.9 1.0 3.6 3.1 0.6 1.5 0.2 0.0 11.5 0.3 0.0 0.1 0.0 3.8 12.0 0.0 4.7 0.0 0.3 3.2 2.1 0.1 0.0 26.2 1.1 13.3 3.1 8.8 0.0 10.9 0.5 0.2 0.5 0.0 0.0 2.2 0.5 1.4 17.3 10.7 0.0 8.0 0.3 35.2 0.9 29.6 0.4 2.4 0.6 22.5 8.7 2.8 2.8 1.5 0.4 111.6 0.0 0.6 17.5 9.0 0.3 1.7 0.6 0.4 0.2 26.3 2.4 3.8 5.5 14.4 0.1 3.4 0.5 3.7 0.1 0.0 0.0 3.9 0.0 0.3 0.0 3.0 0.0 0.0 0.1 1.7 0.3 0.5 0.0 0.2 1.5 1.6 3.1 2.1 1.3 1.5 1.8 1.5 1.8 1.1 1.9 1.0 61.5 6.4 19.8 3.3 16.8 0.0 6.6 0.0 1.8 2.4 180.4 116.3 8.8 22.8 27.2 12.9 0.0 3.8 6.4 18.8 15.6 15.0 2.6 11.6 1.9 34.8 12.2 6.1 0.1 37.1 1.7 2.5 178.9 16.2 1.3 0.6 85.3 2.0 3.5 0.0 0.1 71.9 0.0 5.0 0.0 5.0 2.5 3.8 0.0 3.7 1.2 11.4 0.0 0.0 0.0 25.8 40.5 1.9 24.2 29.6 46.2 4.3 13.1 7.2 13.1 2.4 4.4 2.1 6.5 4.2 0.0 1.8 5.0 1.8 43.6 66.5 CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094142-129111189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.5;tongue: 201.3" "Cell type enhanced" "Detected in many" "Early spermatids: 181.2;Late spermatids: 521.8;Proximal enterocytes: 136.4;Spermatocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Nucleoplasm,Nuclear membrane" NA NA 8100 "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA019230: AB_1847212, HPA020260: AB_1847210, HPA022815: AB_2732427" "unprognostic (5.13e-2)" "unprognostic (9.79e-3)" "unprognostic (1.99e-2)" "prognostic favorable (2.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-2)" "unprognostic (3.13e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (1.26e-2)" "unprognostic (7.65e-2)" 36.1 51.3 26.4 5.4 26.6 9.0 29.2 27.0 33.8 31.7 27.5 36.1 33.0 24.8 4.0 37.3 23.1 6.6 68.2 25.1 27.8 46.9 151.2 15.2 3.2 28.8 28.2 23.0 107.1 26.3 12.3 6.6 30.6 42.2 4.2 1.7 32.8 8.9 227.5 29.6 37.2 6.8 26.7 15.2 34.0 146.4 30.2 3.1 21.5 201.3 1.6 31.3 27.5 24.4 0.1 39.3 10.7 21.3 13.4 25.9 17.0 15.0 16.6 18.9 12.0 7.8 14.0 1.5 9.2 25.9 23.2 6.7 2.2 4.9 7.2 23.6 0.3 7.3 19.1 30.4 34.1 0.0 26.1 26.3 0.0 15.7 0.9 15.8 26.2 7.2 3.6 5.7 20.0 9.1 0.5 15.9 2.8 32.0 18.0 16.8 21.8 12.2 18.0 0.6 4.2 12.1 0.0 7.1 4.8 3.4 49.7 5.5 22.6 23.0 1.6 32.1 15.4 25.5 22.6 0.1 28.8 4.2 16.8 1.6 8.4 3.5 3.2 5.5 6.7 1.5 4.4 4.3 8.6 1.3 2.6 3.1 1.1 4.4 5.6 3.9 4.5 6.1 26.4 26.6 27.0 33.8 25.1 27.8 28.8 28.2 30.6 26.7 30.2 24.4 10.5 6.4 3.7 5.5 4.9 3.2 4.7 10.8 0.6 1.5 9.7 8.1 57.8 21.5 8.2 3.7 2.1 45.9 6.0 64.5 17.6 22.6 181.2 3.5 15.7 12.9 15.5 17.4 5.3 22.4 55.6 19.3 16.8 9.9 7.0 12.9 14.6 65.7 20.7 1.7 6.1 23.6 14.2 13.9 10.5 521.8 22.1 12.4 5.4 6.5 8.3 15.5 6.2 3.5 4.0 11.6 47.6 24.5 9.6 9.3 136.4 52.0 2.8 1.3 6.6 10.5 15.7 123.5 8.6 57.4 4.5 50.3 7.6 20.1 29.3 13.8 CRCT1 "C1orf42, NICE-1" ENSG00000169509 "Cysteine rich C-terminal 1" Q9UGL9 1 152514482-152516008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 579.1;esophagus: 1822.3;vagina: 867.6" "Cell type enhanced" "Detected in some" "Ductal cells: 22.7;Pancreatic endocrine cells: 125.4;Squamous epithelial cells: 44.1;Suprabasal keratinocytes: 37.1" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 68.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "CAPAN-2: 5.0" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (3.01e-2)" "unprognostic (6.92e-2)" "unprognostic (2.86e-2)" "unprognostic (3.30e-1)" "prognostic unfavorable (7.03e-4)" "unprognostic (1.56e-2)" "unprognostic (1.46e-1)" 0.6 0.3 0.0 0.0 0.0 0.0 4.1 0.0 0.0 579.1 0.0 0.3 0.0 0.3 0.0 1822.3 0.2 0.0 0.3 0.0 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.4 1.2 0.0 0.7 0.2 0.0 0.3 0.0 0.0 312.0 0.0 1.0 292.2 0.4 0.0 0.0 0.3 1.2 0.2 0.0 0.0 0.2 0.0 18.4 0.4 867.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.0 0.0 0.0 1.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 125.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 44.1 37.1 0.0 0.0 0.0 0.0 2.0 CREB3L1 OASIS ENSG00000157613 "CAMP responsive element binding protein 3 like 1" Q96BA8 11 46277662-46321409 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.9;salivary gland: 83.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.2;Gastric mucus-secreting cells: 105.0;Glandular and luminal cells: 120.5;Intestinal goblet cells: 280.5" "Cancer enhanced" "Detected in all" "prostate cancer: 87.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 134.3;BJ hTERT+: 130.7;BJ hTERT+ SV40 Large T+: 120.6;fHDF/TERT166: 321.8;OE19: 129.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA024069, CAB026151" Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB026151: , HPA024069: AB_1854750" "unprognostic (2.46e-2)" "unprognostic (2.80e-1)" "unprognostic (1.34e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.66e-3)" "unprognostic (2.93e-1)" "unprognostic (5.41e-2)" "unprognostic (2.75e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.97e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (1.12e-2)" 8.6 15.1 4.3 8.0 3.3 0.1 10.7 0.9 4.2 43.2 2.1 41.2 27.7 20.4 2.4 3.2 5.2 25.0 15.6 7.2 3.4 2.8 1.1 14.8 0.7 1.9 5.1 9.3 133.9 2.3 10.7 26.7 4.1 42.3 43.3 0.1 83.0 26.8 4.4 5.6 30.6 13.3 1.1 3.2 68.0 3.9 8.4 1.0 4.5 4.2 4.7 21.4 15.3 2.4 0.9 0.8 1.3 26.1 81.9 77.9 0.6 134.3 130.7 120.6 83.3 13.7 0.3 0.0 0.7 321.8 8.3 0.0 1.6 0.4 66.6 0.1 1.5 2.0 0.8 0.0 113.5 0.0 1.9 75.2 0.0 68.6 2.5 109.0 1.0 0.5 11.2 0.0 102.5 0.0 0.1 0.4 17.0 129.0 13.7 0.1 18.0 0.2 0.2 0.0 0.0 0.2 0.9 3.4 0.2 23.3 0.1 4.9 0.0 62.7 18.3 48.6 83.4 0.1 0.1 0.0 75.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 3.3 0.9 4.2 7.2 3.4 1.9 5.1 4.1 1.1 8.4 2.4 10.3 0.0 46.4 0.3 0.6 1.5 44.4 2.6 0.0 0.0 52.0 5.1 15.9 25.8 10.0 29.5 0.0 1.2 0.1 56.8 3.9 42.0 2.1 37.2 24.1 9.0 9.1 0.0 2.1 89.2 2.3 49.4 105.0 120.5 4.5 1.9 3.3 0.0 1.9 0.0 1.0 280.5 6.1 0.0 3.5 6.6 83.6 1.0 10.6 2.8 2.0 0.0 0.0 19.6 0.1 49.2 59.8 44.4 0.2 40.4 9.5 0.7 3.6 0.0 0.0 0.7 29.3 1.0 1.5 0.6 2.3 3.4 1.8 10.7 57.7 51.3 CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Adipocytes: 165.7;Basal prostatic cells: 192.2;monocytes: 163.9;Oligodendrocyte precursor cells: 229.7;Oligodendrocytes: 734.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 198.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 198.8" "Cell line enhanced" "Detected in many" "HL-60: 62.5;Karpas-707: 25.0;U-2 OS: 25.7;U-2197: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Plasma membrane" "HPA050020: AB_2680993, HPA061622: AB_2684569" "unprognostic (3.59e-2)" "unprognostic (3.80e-1)" "unprognostic (1.06e-1)" "unprognostic (6.46e-2)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.01e-3)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-1)" "unprognostic (4.91e-3)" "unprognostic (6.61e-2)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" 10.5 1.3 6.3 7.9 20.5 6.1 5.0 6.8 12.7 1.7 0.0 3.5 0.9 8.4 2.8 3.5 2.2 11.4 5.3 9.6 19.9 3.0 1.8 6.1 0.9 19.7 14.6 0.7 3.2 0.2 1.1 3.7 15.8 1.2 1.7 1.3 3.5 1.0 3.2 2.9 2.2 4.7 2.9 7.4 1.4 0.7 23.0 0.7 1.8 4.0 0.8 4.4 2.2 35.0 0.1 0.6 7.3 0.4 0.4 10.3 0.3 0.7 1.6 4.4 6.6 4.2 2.7 18.9 1.3 1.8 4.5 0.7 0.2 6.4 13.8 0.0 5.0 20.4 4.2 0.4 0.4 62.5 0.7 1.3 1.2 18.9 20.1 0.9 3.0 0.1 2.4 25.0 1.5 0.1 0.1 0.0 9.1 0.1 7.4 0.5 6.8 0.5 9.0 2.0 0.7 5.2 0.3 0.4 2.2 10.0 0.2 1.5 0.8 8.6 25.7 28.7 8.5 1.5 4.5 0.2 9.4 0.3 14.8 0.1 29.9 0.0 0.0 9.7 0.0 1.9 0.0 0.0 18.2 0.1 0.0 0.0 198.8 0.0 3.9 0.3 0.0 7.0 6.3 20.5 6.8 12.7 9.6 19.9 19.7 14.6 15.8 2.9 23.0 35.0 165.7 6.4 7.2 10.7 3.2 21.9 192.2 8.2 13.1 1.3 10.7 8.9 16.8 17.2 6.3 12.9 0.0 4.0 0.8 0.0 1.9 74.2 0.4 41.0 56.3 31.3 0.0 0.4 17.0 27.4 13.4 108.0 3.1 69.7 14.0 0.6 14.3 0.5 8.3 5.0 22.2 0.0 6.1 47.4 118.2 1.6 5.9 75.8 30.2 22.5 163.9 14.3 4.1 229.7 734.9 22.5 0.0 0.4 3.2 44.9 0.0 25.6 4.7 0.9 19.7 143.5 31.8 12.6 7.3 12.0 13.2 24.8 3.1 2.6 0.0 35.1 CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355778-36551135 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 163.8" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Hepatic stellate cells: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 466.5;fHDF/TERT166: 462.5;TIME: 651.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA000556: AB_1078567" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (6.39e-2)" "unprognostic (3.17e-3)" "unprognostic (3.88e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (4.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.51e-4)" "unprognostic (1.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.67e-2)" 88.3 14.6 27.0 18.8 28.1 3.5 58.9 9.4 23.5 26.7 51.4 28.7 14.9 26.6 16.7 30.5 34.4 32.2 34.5 20.3 28.8 70.0 16.0 50.1 14.8 23.5 21.9 36.9 23.5 29.2 7.4 163.8 21.2 25.8 23.2 29.5 31.1 32.6 50.1 27.2 18.2 35.7 22.1 47.1 17.5 12.4 36.1 9.9 33.8 36.5 8.7 38.9 22.2 17.1 100.9 75.4 15.2 17.5 69.1 78.0 125.0 466.5 244.7 255.4 133.4 95.3 34.2 0.2 297.9 462.5 166.1 42.8 11.4 75.2 206.5 1.1 8.7 3.2 96.7 55.5 221.5 2.2 0.6 110.1 55.2 102.4 182.4 238.4 361.9 1.9 4.7 0.7 271.6 9.2 0.2 1.2 11.9 5.2 22.1 5.4 19.6 15.5 159.8 41.1 1.8 0.2 81.5 26.4 3.4 56.2 72.3 2.0 651.1 321.7 116.1 40.4 229.1 25.5 0.5 0.9 94.7 0.4 100.8 1.4 0.1 0.5 0.6 0.0 0.4 0.3 0.2 0.3 0.1 0.2 0.0 0.3 0.2 0.4 0.6 2.1 0.2 0.0 27.0 28.1 9.4 23.5 20.3 28.8 23.5 21.9 21.2 22.1 36.1 17.1 262.9 12.8 43.3 100.2 5.4 66.0 38.5 30.1 43.9 12.0 55.6 72.9 34.4 47.1 26.5 132.4 2.1 111.9 27.1 49.5 3.9 33.5 1.0 37.1 27.7 159.8 31.8 10.7 85.1 2.6 40.6 41.0 10.2 75.9 1.3 27.4 207.1 3.6 27.7 0.0 57.5 37.7 36.7 7.7 32.5 2.0 19.0 8.2 39.2 135.9 7.1 18.5 6.2 65.9 17.2 26.5 30.9 19.9 6.9 75.5 11.5 38.4 28.9 42.5 46.0 18.4 164.6 2.1 9.4 22.0 30.1 173.5 17.1 5.7 33.2 58.3 CRISP2 "CRISP-2, CT36, GAPDL5, TPX1" ENSG00000124490 "Cysteine rich secretory protein 2" P16562 6 49692358-49713590 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "testis: 505.0" "Group enriched" "Detected in some" 33 "Early spermatids: 5765.5;Late spermatids: 21517.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031248 Enhanced "Secreted in male reproductive system" NA NA 820000 "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA031248: AB_10602211" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (7.38e-2)" "unprognostic (2.35e-2)" "unprognostic (9.23e-3)" "unprognostic (4.05e-2)" 0.1 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 1.9 0.7 0.0 0.1 0.2 0.9 3.6 17.6 7.7 0.1 0.0 0.2 0.8 0.2 1.2 0.0 0.1 0.1 0.1 0.6 0.0 2.0 0.0 0.0 1.2 0.0 0.1 15.6 2.5 0.2 0.5 0.3 0.0 0.0 0.5 0.1 505.0 0.1 0.0 0.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 0.1 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5765.5 17.8 0.5 6.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 21517.6 133.9 6.1 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 83.8 0.0 2.8 0.2 0.1 24.1 0.0 65.7 0.0 0.0 409.8 65.1 0.0 0.0 0.0 0.0 0.0 0.3 2.3 CRISP3 "Aeg2, CRISP-3, CRS3, dJ442L6.3, SGP28" ENSG00000096006 "Cysteine rich secretory protein 3" P54108 6 49727376-49744437 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 1203.8;salivary gland: 2310.0" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 182.2;Glandular and luminal cells: 551.5" "Group enriched" "Detected in many" 7 "breast cancer: 31.9;pancreatic cancer: 59.8;prostate cancer: 85.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "neutrophil: 2.5;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 19 "granulocytes: 2.5;monocytes: 1.2" "Group enriched" "Detected in some" 20 "HEL: 12.3;RT4: 4.1;SK-BR-3: 9.3;T-47d: 4.4" "Not detected" "Not detected" HPA054392 Supported "Secreted in other tissues" NA NA 420000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" "HPA054392: AB_2682472" "unprognostic (1.28e-2)" "unprognostic (7.01e-2)" "unprognostic (8.93e-2)" "unprognostic (5.56e-2)" "unprognostic (1.02e-1)" "unprognostic (2.22e-4)" "unprognostic (5.30e-2)" "unprognostic (6.70e-2)" "unprognostic (9.16e-2)" "unprognostic (4.34e-3)" "unprognostic (1.91e-1)" "unprognostic (1.93e-1)" 0.3 0.6 0.0 0.0 0.0 381.8 3.9 0.0 0.0 61.0 0.0 0.1 0.4 1.7 0.1 266.8 1203.8 23.1 0.8 0.0 0.0 0.1 0.9 1.3 0.0 0.0 0.0 0.5 5.5 0.0 0.5 0.6 0.0 2.9 0.0 0.0 2310.0 111.9 0.3 3.9 0.2 0.0 0.0 2.5 0.3 0.2 0.0 0.3 0.2 0.0 4.0 4.7 140.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 9.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.0 2.1 5.6 0.0 21.5 13.1 3.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 182.2 47.2 0.8 0.0 0.4 0.0 3.7 0.0 0.2 0.0 551.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 26.8 CRISPLD1 "Cocoacrisp, DKFZp762F133, LCRISP1" ENSG00000121005 "Cysteine rich secretory protein LCCL domain containing 1" Q9H336 8 74984505-75034558 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 29.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 36.1;Endometrial ciliated cells: 62.2;Oligodendrocyte precursor cells: 81.4" "Cancer enhanced" "Detected in many" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 134.4;SH-SY5Y: 72.0;SuSa: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024725 Uncertain "Secreted - unknown location" NA NA 8200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA024725: AB_1847238" "unprognostic (2.16e-1)" "unprognostic (5.88e-2)" "unprognostic (4.01e-2)" "unprognostic (3.78e-2)" "unprognostic (3.85e-2)" "unprognostic (1.65e-1)" "unprognostic (2.09e-4)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (5.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (7.39e-3)" "unprognostic (2.38e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" 2.7 1.3 3.9 2.5 4.0 1.5 29.4 3.4 3.1 6.3 3.4 2.7 0.7 8.6 4.9 5.0 7.4 10.0 8.8 4.3 8.0 2.1 2.1 2.3 2.8 5.8 10.4 5.7 2.4 19.3 1.2 7.8 8.3 24.6 1.6 3.1 19.3 2.6 0.5 2.3 1.2 7.0 6.3 2.0 0.9 3.8 4.1 9.4 15.1 1.2 1.1 2.5 1.1 10.7 0.0 1.7 134.4 0.0 0.0 0.0 4.5 0.0 0.0 1.6 1.9 0.8 0.0 0.0 19.0 0.0 2.2 0.1 11.3 0.1 0.0 0.1 5.2 0.2 5.1 0.0 3.0 0.0 1.0 7.2 0.3 0.1 1.0 16.6 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.2 13.9 0.0 5.0 0.0 18.5 0.2 0.0 0.0 0.8 72.0 0.0 0.1 8.0 27.5 10.4 6.4 0.0 3.8 19.6 0.2 0.5 2.4 0.9 0.0 4.6 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.9 4.0 3.4 3.1 4.3 8.0 5.8 10.4 8.3 6.3 4.1 10.7 1.0 3.2 0.0 12.7 0.0 0.8 6.1 1.4 17.6 1.6 10.3 36.1 0.4 0.0 5.4 1.8 0.0 22.7 0.3 0.0 0.0 0.0 15.3 62.2 4.9 3.2 0.0 3.0 15.7 0.0 3.8 9.2 0.0 22.4 3.8 1.8 23.6 0.1 2.0 0.0 11.1 0.0 0.0 0.9 0.0 1.5 4.1 0.4 7.2 1.9 0.0 8.8 0.0 81.4 0.9 0.0 0.0 1.5 0.0 9.4 0.0 0.2 22.5 0.9 0.0 0.4 1.5 1.3 6.0 2.5 1.0 12.0 0.4 6.3 0.0 2.3 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CSGALNACT1 "ChGn, CSGalNAcT-1, FLJ11264" ENSG00000147408 "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" Q8TDX6 8 19404161-19758029 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 86.7" "Cell type enhanced" "Detected in many" "Astrocytes: 494.3;Excitatory neurons: 144.4;Granulosa cells: 214.1;Microglial cells: 224.9;Oligodendrocyte precursor cells: 355.9" "Cancer enhanced" "Detected in all" "prostate cancer: 22.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 62.6" "Group enriched" "Detected in all" 5 "B-cells: 44.5;granulocytes: 24.9;T-cells: 62.6" "Cell line enhanced" "Detected in many" "A549: 57.8;BJ hTERT+: 32.3;GAMG: 22.9;RPTEC TERT1: 39.6;U-2197: 36.8;U-87 MG: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068462 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Golgi apparatus" "HPA068462: " "unprognostic (8.90e-2)" "unprognostic (1.57e-2)" "unprognostic (4.66e-2)" "unprognostic (2.58e-1)" "unprognostic (6.03e-2)" "unprognostic (3.17e-3)" "unprognostic (9.78e-2)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (1.46e-3)" "unprognostic (1.02e-2)" 19.4 12.5 20.3 8.8 15.7 11.1 7.4 4.8 18.3 18.0 0.7 4.7 3.5 7.0 5.4 31.2 11.8 16.1 35.8 16.3 11.5 6.0 2.8 11.7 7.6 6.3 11.2 57.0 7.9 11.4 3.0 38.8 7.6 31.8 2.5 2.5 6.8 9.8 5.8 4.8 4.7 12.3 6.7 8.7 6.9 2.8 8.9 11.7 86.7 11.0 8.8 23.4 8.1 10.7 2.1 57.8 0.5 0.0 9.3 2.1 7.9 1.4 32.3 0.3 0.3 3.1 1.0 0.0 0.3 0.0 22.9 0.7 0.0 0.0 0.4 7.5 0.4 0.2 16.2 1.9 4.1 0.0 0.1 0.9 1.6 0.7 0.3 0.4 11.6 0.2 0.0 0.1 0.1 2.6 2.9 0.2 0.3 8.3 1.7 0.3 0.1 0.0 39.6 1.6 0.2 0.3 17.2 6.9 2.4 1.5 0.1 0.4 1.0 1.1 1.3 36.8 0.9 0.3 0.0 0.0 26.0 3.4 11.4 0.1 2.9 24.9 5.6 0.1 0.6 44.5 25.7 8.5 2.8 15.9 44.6 11.6 15.6 8.4 0.4 4.2 62.6 11.7 20.3 15.7 4.8 18.3 16.3 11.5 6.3 11.2 7.6 6.7 8.9 10.7 33.3 3.2 1.1 494.3 27.3 4.5 7.4 0.2 0.6 0.3 4.1 0.8 45.8 0.0 0.9 12.9 10.4 1.9 6.2 0.0 1.9 5.7 6.9 7.5 1.2 38.5 3.0 3.2 144.4 1.7 14.6 20.9 2.0 2.0 0.0 214.1 26.7 0.2 15.8 18.5 76.5 0.0 16.2 27.4 6.5 7.4 5.3 14.1 12.4 224.9 3.5 1.0 6.2 355.9 4.6 3.1 0.0 12.0 21.3 21.8 0.0 0.1 1.5 1.0 6.6 2.1 12.0 0.7 0.1 0.5 3.1 8.3 9.6 77.0 0.1 2.8 CSMD1 "KIAA1890, PPP1R24" ENSG00000183117 "CUB and Sushi multiple domains 1" Q96PZ7 8 2935353-4994972 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 10.7" "Group enriched" "Detected in some" 20 "Excitatory neurons: 4868.4;Inhibitory neurons: 3913.1;Oligodendrocyte precursor cells: 4521.8" "Cancer enhanced" "Detected in some" "testis cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.9;U-2 OS: 2.2;U-266/70: 2.2;U-266/84: 2.1;U-698: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074707 Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA074707: AB_2686707" "unprognostic (6.32e-2)" "unprognostic (4.23e-2)" "unprognostic (2.37e-1)" "unprognostic (1.67e-3)" "unprognostic (5.72e-2)" "unprognostic (4.26e-2)" "unprognostic (1.02e-2)" "unprognostic (4.66e-2)" "unprognostic (7.69e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-1)" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (2.74e-2)" "unprognostic (5.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.11e-1)" 0.1 0.0 3.5 0.0 5.8 0.0 0.2 0.0 10.7 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 5.8 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.0 1.6 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.6 0.0 2.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.2 0.0 0.0 2.2 2.1 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 0.0 10.7 5.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.6 0.0 0.5 108.4 0.0 0.3 0.0 0.0 2.2 15.0 1.0 0.9 2.2 0.0 0.6 1.8 0.0 3.4 0.0 0.1 0.0 0.0 52.5 1.5 0.3 2.2 0.0 0.0 4868.4 0.0 1.3 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 3913.1 0.1 0.0 0.0 0.7 15.0 0.3 0.2 0.0 220.2 0.7 0.5 0.0 4521.8 135.2 0.0 0.1 0.4 0.0 0.0 0.0 1.2 9.7 0.6 0.0 0.2 0.5 10.2 5.3 1.0 0.1 3.6 0.1 2.8 0.0 0.1 CSNK2A1 "Cka1, Cka2" ENSG00000101266 "Casein kinase 2 alpha 1" P68400 20 472498-543835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020680, HPA059206, HPA061698, CAB069395" Supported Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "CAB020680: , CAB069395: AB_1611912, HPA059206: AB_2683948, HPA061698: AB_2732667" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (5.44e-2)" "unprognostic (8.28e-3)" "unprognostic (3.62e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (4.11e-6)" "unprognostic (4.08e-2)" "unprognostic (3.89e-1)" "unprognostic (6.88e-2)" "unprognostic (1.94e-2)" "unprognostic (1.16e-1)" "unprognostic (8.58e-2)" "unprognostic (1.50e-1)" "unprognostic (4.47e-1)" "unprognostic (9.53e-2)" "unprognostic (7.37e-2)" 36.1 32.6 20.9 38.6 23.2 34.0 35.9 28.2 29.6 36.5 29.3 48.3 39.1 35.8 26.6 50.0 39.9 31.3 54.0 25.7 21.0 41.0 31.8 31.6 41.2 20.6 21.1 41.5 46.9 59.1 21.2 42.4 21.1 35.8 40.7 32.9 41.1 37.7 110.5 34.2 40.5 39.1 18.8 30.2 49.5 65.2 22.3 51.6 39.6 86.4 46.6 47.4 28.5 27.3 209.5 170.4 152.9 96.0 61.1 103.8 103.5 117.9 116.1 125.8 139.5 178.5 120.0 179.1 74.2 90.1 179.1 147.8 162.1 167.4 187.2 62.6 57.7 247.3 44.7 177.7 102.5 228.1 51.3 99.5 173.3 105.8 316.0 122.2 139.5 146.4 248.9 112.6 123.8 64.2 262.0 73.7 227.4 173.4 97.6 149.8 140.5 140.9 112.9 128.5 163.9 132.3 97.2 184.0 174.8 120.7 120.4 83.9 142.7 136.0 118.4 90.0 178.5 120.6 311.8 174.1 65.8 119.5 138.6 40.5 23.8 28.7 18.2 32.3 22.4 23.0 18.0 17.6 31.5 22.5 17.9 17.4 14.9 25.1 33.5 25.7 20.4 20.8 20.9 23.2 28.2 29.6 25.7 21.0 20.6 21.1 21.1 18.8 22.3 27.3 50.7 64.1 84.6 51.9 46.1 41.0 40.0 43.8 45.5 49.4 42.1 36.1 59.4 41.5 75.8 44.1 31.3 42.2 50.5 43.5 41.1 68.5 135.5 67.6 77.0 44.5 35.2 59.3 65.6 50.6 54.4 46.3 40.2 75.7 63.8 108.6 27.1 31.1 33.2 60.6 69.3 41.8 46.8 39.2 30.3 140.0 41.0 45.3 14.2 51.5 61.7 38.6 37.0 73.9 73.6 66.6 34.4 36.9 49.6 57.2 43.2 68.8 65.5 27.8 52.6 43.6 56.8 94.2 68.7 52.3 50.2 61.4 38.9 81.2 40.6 59.4 CSNK2A2 "CK2alpha', CSNK2A1" ENSG00000070770 "Casein kinase 2 alpha 2" P19784 16 58157907-58198106 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 112.7" "Group enriched" "Detected in all" 5 "Early spermatids: 227.4;Late spermatids: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 92000 "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" "unprognostic (9.49e-2)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.40e-5)" "prognostic unfavorable (1.80e-4)" "unprognostic (6.84e-3)" "unprognostic (2.93e-3)" "unprognostic (2.40e-1)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (2.06e-3)" "unprognostic (7.07e-2)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" 21.0 14.1 19.3 9.0 20.2 6.4 19.0 18.9 22.1 23.0 23.7 32.1 10.0 21.0 29.0 15.7 20.3 14.1 21.2 20.0 19.7 17.3 15.9 16.2 14.2 19.1 20.4 32.4 34.2 23.9 15.7 15.5 19.2 15.5 12.4 13.5 17.0 16.7 41.1 64.8 14.2 21.9 19.8 12.6 27.9 112.7 20.3 18.3 18.0 26.8 17.3 24.2 19.6 19.9 28.1 35.3 24.5 19.1 46.2 62.5 27.6 24.7 41.8 47.7 30.7 64.0 23.2 44.2 38.8 29.6 18.9 29.2 41.6 37.2 53.4 16.9 28.3 23.4 18.0 56.1 66.5 32.6 20.5 66.9 88.9 33.8 65.9 62.0 45.4 43.6 53.4 15.1 31.0 15.8 41.2 21.9 23.4 16.6 45.7 48.4 38.7 25.7 33.1 28.7 20.5 18.4 39.7 20.3 63.6 41.9 13.9 24.6 33.6 27.8 33.7 23.3 25.7 36.2 30.2 63.2 24.3 21.8 24.4 1.1 0.2 0.3 0.7 0.1 0.4 0.6 1.1 0.4 0.2 0.6 1.8 1.3 0.0 0.7 0.1 1.9 0.0 0.1 19.3 20.2 18.9 22.1 20.0 19.7 19.1 20.4 19.2 19.8 20.3 19.9 30.6 12.8 22.5 19.2 16.7 29.6 10.9 13.0 8.6 24.0 19.3 19.9 24.4 12.8 7.6 9.2 4.2 15.9 28.3 16.4 7.9 14.5 227.4 24.7 37.8 25.8 16.8 10.3 27.7 17.2 26.1 17.7 8.6 29.5 8.2 37.0 19.6 17.0 16.9 18.5 19.1 11.9 4.1 25.5 23.0 281.0 14.3 23.1 12.4 20.6 14.2 25.3 18.6 20.6 26.1 25.0 11.5 19.5 9.2 18.1 16.0 16.3 13.4 21.7 13.1 29.2 23.2 48.1 36.8 12.6 29.0 24.5 20.3 35.6 17.5 23.0 CSPG5 NGC ENSG00000114646 "Chondroitin sulfate proteoglycan 5" O95196 3 47562238-47580792 "Predicted membrane proteins" "Differentiation, Growth regulation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 83.2;choroid plexus: 65.2;retina: 28.3" "Group enriched" "Detected in some" 4 "Astrocytes: 67.6;Muller glia cells: 94.7;Oligodendrocyte precursor cells: 233.7" "Cancer enriched" "Detected in many" 19 "glioma: 48.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 32.6;HEK 293: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049529, HPA067818, HPA071779" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm Mitochondria "HPA049529: AB_2680805, HPA067818: AB_2685905, HPA071779: AB_2686446" "unprognostic (2.68e-1)" "unprognostic (2.11e-1)" "unprognostic (8.87e-2)" "unprognostic (3.12e-2)" "unprognostic (2.88e-1)" "unprognostic (7.66e-2)" "unprognostic (5.05e-4)" "unprognostic (1.40e-1)" "unprognostic (3.82e-1)" "prognostic favorable (2.14e-4)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (3.41e-4)" "unprognostic (8.08e-2)" "unprognostic (1.01e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" 0.9 0.8 58.3 0.2 62.4 0.1 0.6 33.6 83.2 0.3 65.2 1.1 0.0 0.3 0.1 0.3 0.3 0.1 0.5 62.5 49.7 0.2 0.2 3.2 0.2 41.2 45.6 0.2 0.3 0.3 1.7 0.8 45.8 0.4 0.2 28.3 0.3 0.0 0.5 1.1 0.3 0.4 37.0 0.0 0.4 1.9 48.0 0.1 0.4 0.0 0.1 0.1 0.2 46.1 0.3 1.7 32.6 5.7 0.6 0.0 0.9 0.6 0.1 1.2 0.3 0.3 2.0 0.1 2.5 0.1 2.4 0.5 2.7 0.3 0.3 0.0 8.8 0.5 1.4 0.0 0.0 0.4 1.4 0.0 1.1 0.1 0.0 0.9 0.1 1.1 6.6 0.3 0.1 1.5 0.2 0.4 3.1 2.4 3.3 0.5 0.2 0.7 1.4 1.1 3.4 1.5 2.1 4.1 0.1 0.9 1.6 3.1 0.3 0.1 6.5 0.1 1.9 0.8 0.8 0.0 0.5 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.3 62.4 33.6 83.2 62.5 49.7 41.2 45.6 45.8 37.0 48.0 46.1 0.7 3.2 2.0 67.6 0.1 0.8 0.1 0.0 0.0 28.6 2.2 1.8 1.3 0.0 0.0 0.0 6.2 0.2 0.0 0.5 0.0 0.2 2.0 0.6 0.6 0.3 1.8 0.0 18.6 0.0 0.2 0.5 0.0 2.0 0.0 6.1 0.0 0.5 0.2 6.7 25.0 0.3 0.0 0.0 0.2 0.6 0.3 0.2 0.0 7.5 0.0 94.7 0.0 233.7 9.9 0.4 0.1 0.0 0.0 0.2 0.0 0.1 0.0 22.7 0.0 0.8 0.8 13.5 3.3 0.0 0.6 0.1 0.2 0.2 0.4 0.1 CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 18746.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Cell line enhanced" "Detected in many" "ASC diff: 1733.4;ASC TERT1: 1179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" 1046.2 707.6 3041.2 262.3 3117.9 170.8 900.3 2823.3 4217.6 587.8 3094.8 788.7 389.6 708.3 875.9 557.1 802.7 583.0 1275.3 2976.3 2707.6 517.4 833.6 595.8 463.5 3258.4 3096.2 575.8 944.1 320.0 670.1 165.9 2939.3 773.9 416.9 46.9 2008.0 441.5 749.0 497.1 800.3 367.6 3028.1 723.7 979.9 761.3 3302.7 418.9 658.8 517.4 208.1 703.0 618.4 2883.1 155.2 328.2 75.4 175.8 1733.4 1179.8 145.3 261.4 350.7 170.3 137.7 625.1 219.7 0.8 241.0 345.2 221.3 496.2 69.6 499.9 51.9 0.9 253.5 157.6 61.1 1082.9 621.2 7.5 251.0 919.0 415.9 226.6 241.5 352.5 268.5 18.5 147.6 4.0 239.5 234.4 1.5 162.2 103.5 461.9 752.2 5.7 96.4 215.2 708.0 328.3 84.7 98.2 191.1 54.6 343.3 107.7 156.5 548.2 702.0 163.4 119.0 231.6 97.7 157.1 6.2 1.8 138.0 339.5 184.0 48.1 4967.5 33.2 66.9 6424.5 25.5 23.1 18.3 45.8 7959.0 13.6 16.9 31.1 809.3 191.4 4297.7 4427.4 13.6 4250.8 3041.2 3117.9 2823.3 4217.6 2976.3 2707.6 3258.4 3096.2 2939.3 3028.1 3302.7 2883.1 662.4 115.4 168.8 849.5 93.8 942.9 571.1 568.2 213.9 152.4 660.2 512.1 240.7 1361.2 514.5 641.9 29.2 476.8 603.3 1889.9 414.8 489.9 46.2 441.1 795.0 728.2 882.1 252.1 4.5 783.6 308.7 3026.2 981.7 631.0 359.9 687.0 491.9 2563.0 1816.7 48.8 11.2 1360.6 691.7 4301.1 18746.6 184.3 2132.6 4542.6 1563.5 87.1 2025.6 248.7 99.9 263.9 6.0 1458.5 2342.1 1790.4 67.9 786.0 4301.1 1098.6 364.4 36.3 2195.7 1417.0 846.2 125.5 400.6 461.5 822.0 469.0 117.4 208.1 1039.4 1079.7 CSTA "STF1, STFA" ENSG00000121552 "Cystatin A" P01040 3 122325248-122341969 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5912.9;vagina: 1853.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2493.8;Club cells: 768.0;Kupffer cells: 579.4;monocytes: 1298.6;Squamous epithelial cells: 3020.6" "Cancer enhanced" "Detected in all" "cervical cancer: 227.7;head and neck cancer: 405.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "classical monocyte: 514.7;intermediate monocyte: 269.1;myeloid DC: 382.9;neutrophil: 245.6;non-classical monocyte: 161.7" "Group enriched" "Detected in all" 193 "dendritic cells: 382.9;granulocytes: 245.6;monocytes: 514.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 282.0;hTCEpi: 1218.6;THP-1: 789.0;U-698: 504.5;U-937: 250.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000469, HPA001031, CAB047315" Enhanced Approved Nucleoplasm,Cytosol No No 28000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "CAB000469: , CAB047315: , HPA001031: AB_1078610" "unprognostic (5.22e-3)" "unprognostic (6.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.07e-2)" "unprognostic (7.79e-3)" "prognostic favorable (5.86e-4)" "unprognostic (4.46e-1)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (7.99e-2)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (8.89e-2)" "unprognostic (3.43e-2)" "unprognostic (9.24e-3)" "unprognostic (1.99e-1)" 30.7 4.7 0.8 27.1 0.9 297.8 56.3 1.0 3.7 961.0 1.4 3.8 1.1 2.2 10.3 5912.9 4.6 7.2 5.9 0.8 1.0 2.4 38.9 26.0 25.1 1.5 0.9 21.1 3.7 0.8 5.0 19.0 1.3 19.7 3.6 0.3 996.1 9.6 4.6 369.1 5.8 6.3 1.1 20.4 30.3 1.3 1.4 46.5 2.7 2.8 941.0 39.1 1853.3 1.6 14.6 1.3 0.2 3.2 31.5 58.0 2.9 0.6 0.8 0.0 0.0 0.0 0.0 3.2 7.6 5.9 0.5 86.9 0.0 282.0 0.0 0.3 0.2 0.7 0.0 6.8 6.8 117.6 1.9 30.5 1218.6 2.9 119.1 0.0 0.0 1.5 0.8 29.9 0.5 0.8 0.2 108.3 0.0 0.5 0.0 0.0 0.9 0.0 0.0 141.3 0.0 0.0 14.1 7.5 10.4 0.1 1.6 789.0 0.5 1.7 19.7 0.2 0.9 0.0 1.7 504.5 26.4 250.3 0.3 8.8 514.7 16.4 0.6 269.1 1.5 1.5 0.7 0.6 382.9 0.5 0.5 0.7 245.6 1.9 161.7 6.9 1.0 283.2 0.8 0.9 1.0 3.7 0.8 1.0 1.5 0.9 1.3 1.1 1.4 1.6 1.1 6.4 19.8 0.0 5.0 83.5 136.5 2493.8 117.8 0.0 7.1 119.8 0.2 2.8 768.0 0.0 0.0 230.6 7.4 3.9 0.0 2.1 0.4 0.3 0.4 3.0 0.0 3.8 0.1 22.1 17.8 13.6 12.8 0.3 13.9 0.1 6.1 96.0 134.5 0.0 0.1 0.5 179.0 579.4 90.6 2.4 10.2 243.7 8.8 0.0 1298.6 0.0 20.6 0.5 0.2 46.2 1.5 3.8 2.8 30.2 0.0 0.7 115.7 0.0 32.9 8.8 24.3 0.1 0.5 3020.6 205.0 334.2 4.9 26.1 2.0 134.1 CTBP2 ribeye ENSG00000175029 "C-terminal binding protein 2" P56545 10 124984317-125161170 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023559, HPA023564, CAB031916, HPA044971, CAB079018" Approved Approved Approved Nucleoplasm NA NA 10000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB031916: AB_2086774, CAB079018: , HPA023559: AB_1847309, HPA023564: AB_1847310, HPA044971: AB_2679161" "unprognostic (8.69e-2)" "unprognostic (1.27e-2)" "unprognostic (4.14e-2)" "unprognostic (1.41e-2)" "unprognostic (6.84e-3)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (5.60e-3)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (3.24e-2)" "unprognostic (3.99e-3)" "prognostic favorable (1.70e-4)" "unprognostic (4.34e-2)" "unprognostic (1.48e-1)" "unprognostic (2.19e-2)" "unprognostic (1.62e-1)" 27.1 25.4 21.4 17.1 23.7 17.2 30.6 32.9 20.1 47.9 47.8 36.7 33.3 46.8 21.0 30.4 37.3 22.1 19.9 22.8 25.5 31.7 5.7 33.1 9.4 24.3 24.1 41.8 40.7 21.9 23.6 24.7 22.0 38.6 29.2 55.4 36.7 24.0 22.8 16.7 33.4 30.0 22.1 21.6 36.9 19.7 28.8 9.0 53.9 19.8 9.1 29.9 30.9 23.7 87.3 96.5 83.6 70.2 43.9 43.0 46.1 66.4 77.0 61.2 69.3 60.4 99.7 0.1 33.6 66.9 38.6 67.2 83.8 106.5 45.8 0.3 63.8 63.8 61.6 1.3 91.7 27.2 48.9 37.1 82.7 63.5 125.5 80.9 79.1 4.9 2.6 0.5 38.7 96.5 3.0 27.8 63.0 90.3 61.3 77.4 35.0 0.8 72.5 38.8 25.5 73.1 64.7 56.0 86.5 64.7 39.7 43.9 64.4 36.8 46.2 53.0 57.9 1.4 5.3 0.3 46.1 0.3 37.1 30.8 8.5 16.4 8.5 9.0 1.1 0.5 0.4 2.3 11.2 0.3 0.5 3.6 14.3 34.6 22.4 9.4 0.3 4.7 21.4 23.7 32.9 20.1 22.8 25.5 24.3 24.1 22.0 22.1 28.8 23.7 64.7 32.1 27.2 72.1 4.0 47.2 83.4 41.5 33.6 182.5 75.8 59.8 32.7 55.8 53.2 38.6 158.4 22.3 50.7 81.7 68.4 69.3 29.9 125.0 65.1 63.0 55.0 42.3 41.8 60.8 70.5 42.3 40.2 163.0 17.7 43.1 61.4 1.2 29.6 107.7 35.0 93.9 50.8 49.3 46.9 38.1 60.3 47.0 58.7 127.4 60.6 63.2 124.6 44.2 87.1 83.8 61.6 77.8 6.9 89.3 45.1 31.6 94.1 107.5 59.2 59.6 67.0 12.7 45.5 42.1 39.8 19.3 15.3 81.3 106.1 102.7 CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in many" "Muller glia cells: 185.7;Suprabasal keratinocytes: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Vesicles" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" 34.4 11.1 29.7 11.2 28.2 22.4 35.2 37.3 31.2 59.2 13.1 15.0 18.8 11.8 77.4 177.7 12.5 10.3 43.8 29.5 30.0 17.6 15.7 26.4 8.7 33.8 29.0 14.6 35.9 10.9 19.7 28.2 36.4 24.5 10.2 27.5 53.1 14.1 39.0 434.9 14.9 10.9 27.1 9.3 22.8 27.0 37.5 19.6 21.0 22.3 25.1 13.3 85.1 27.3 74.8 10.9 65.9 50.4 9.8 16.2 21.1 14.4 25.2 20.9 13.3 5.4 92.6 22.9 41.0 18.7 21.6 37.3 7.7 85.9 9.6 58.0 11.9 14.9 3.4 69.3 20.3 11.3 8.4 18.2 83.5 26.7 27.0 17.7 57.2 42.4 26.8 10.5 13.0 45.6 25.3 41.6 35.0 60.0 18.7 28.4 19.3 14.7 10.7 25.2 72.1 45.4 32.9 29.4 44.4 22.3 36.3 27.2 37.7 13.4 16.4 20.4 32.2 22.9 32.5 27.0 5.0 56.6 54.5 2.6 5.2 13.8 2.6 1.8 1.6 1.7 1.3 2.1 6.4 1.5 1.3 1.2 3.7 8.6 1.2 2.0 1.3 2.6 29.7 28.2 37.3 31.2 29.5 30.0 33.8 29.0 36.4 27.1 37.5 27.3 150.6 28.9 13.9 30.0 9.6 103.1 42.3 16.1 40.5 9.0 39.9 33.3 14.0 24.3 17.0 18.4 8.4 71.3 23.5 20.5 33.2 20.9 116.3 20.0 17.9 42.7 49.1 20.0 18.0 18.7 43.2 15.7 30.1 38.5 0.0 27.2 20.0 25.6 58.0 16.8 14.1 37.5 12.2 43.0 97.4 34.8 14.9 38.3 48.0 12.2 33.6 185.7 71.1 17.1 24.1 37.6 28.3 23.0 13.3 53.5 28.6 30.5 5.2 12.8 46.0 15.0 24.5 72.1 43.6 154.0 291.5 48.4 17.2 14.3 28.6 60.5 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 72.6 48.8 29.6 34.8 28.1 5.9 83.3 28.2 33.0 86.0 50.0 107.9 97.8 70.8 49.3 209.7 58.4 56.3 49.0 26.6 26.8 77.9 82.6 83.9 19.0 34.8 30.6 49.3 120.0 76.1 57.7 106.0 32.5 78.9 102.0 23.5 121.8 57.1 26.8 129.4 104.9 54.8 32.3 51.5 105.4 44.3 38.0 24.4 98.6 19.9 48.4 83.5 111.9 33.5 156.6 106.4 70.2 63.3 46.1 71.6 141.7 65.1 78.8 58.5 55.6 88.5 163.9 1.0 113.2 72.5 50.9 201.7 58.8 97.4 71.1 1.0 21.9 32.0 35.8 109.9 52.6 5.0 52.7 70.0 133.5 67.1 73.5 103.8 197.2 1.7 55.1 0.4 55.1 48.0 1.7 13.9 54.7 101.2 56.5 0.7 67.4 1.3 90.2 171.0 4.9 40.1 91.5 133.6 113.1 176.3 138.9 6.1 166.0 59.6 50.3 53.2 34.6 1.2 0.9 2.3 53.2 3.4 111.5 0.0 4.9 0.1 0.0 9.5 0.2 0.2 0.0 0.1 6.3 0.3 0.0 0.0 0.2 0.4 5.6 1.4 0.1 1.1 29.6 28.1 28.2 33.0 26.6 26.8 34.8 30.6 32.5 32.3 38.0 33.5 116.2 147.4 84.0 0.0 8.8 117.1 96.9 82.9 126.9 21.0 101.5 70.5 17.5 125.8 96.6 141.6 39.6 94.0 2.3 305.5 13.7 106.7 14.1 91.1 58.5 98.6 86.2 21.3 0.0 97.2 85.6 34.5 165.1 139.4 32.4 61.1 91.8 127.6 44.4 15.2 0.0 160.7 52.9 64.3 55.5 10.5 28.3 46.4 48.0 0.0 28.5 30.2 2.1 0.0 0.0 141.8 169.3 38.4 5.0 116.9 179.6 57.6 88.2 26.4 26.3 32.3 38.1 37.0 21.1 285.1 200.5 90.8 6.2 39.9 127.0 194.6 CTNND2 "GT24, NPRAP" ENSG00000169862 "Catenin delta 2" Q9UQB3 5 10971836-11904446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 93.8" "Cell type enhanced" "Detected in many" "Astrocytes: 2382.9;Excitatory neurons: 1253.9;Inhibitory neurons: 1124.0;Oligodendrocyte precursor cells: 1418.0;Oligodendrocytes: 433.8" "Cancer enriched" "Detected in many" 16 "glioma: 44.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.1;MCF7: 9.0;SK-BR-3: 5.3;U-266/84: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015077, CAB037339, HPA071124" Enhanced Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cell Junctions" Cytosol "CAB037339: , HPA015077: AB_2669150, HPA071124: " "unprognostic (7.32e-2)" "unprognostic (1.51e-3)" "unprognostic (2.23e-1)" "unprognostic (5.16e-2)" "unprognostic (5.66e-2)" "unprognostic (2.06e-2)" "unprognostic (1.81e-1)" "unprognostic (2.74e-2)" "unprognostic (9.13e-2)" "unprognostic (9.86e-2)" "unprognostic (8.95e-3)" "unprognostic (2.66e-1)" "unprognostic (9.55e-4)" "unprognostic (5.87e-2)" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (4.76e-2)" 0.2 0.7 79.2 0.2 79.3 0.0 0.9 49.7 75.7 0.1 15.2 1.1 0.1 0.1 0.3 0.1 0.2 2.6 3.8 84.6 56.7 0.0 0.5 0.7 0.1 93.8 72.6 0.5 15.8 0.0 9.0 0.3 71.5 0.9 0.3 7.0 0.8 0.2 0.1 0.7 0.5 0.1 77.7 3.9 0.6 2.6 83.7 0.2 0.2 0.1 0.0 0.1 0.2 76.1 0.0 0.2 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 9.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 5.3 0.0 0.6 0.0 0.0 0.0 0.0 1.0 0.0 3.4 0.0 17.5 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.2 79.3 49.7 75.7 84.6 56.7 93.8 72.6 71.5 77.7 83.7 76.1 0.1 0.0 0.0 2382.9 0.1 0.0 0.1 0.0 0.0 24.0 7.9 4.1 12.7 28.6 0.0 1.8 0.0 0.0 0.0 0.1 3.9 6.5 25.6 0.8 0.1 0.8 4.9 0.0 1253.9 6.1 0.2 0.5 0.0 0.9 0.0 0.0 0.0 0.2 0.1 8.4 1124.0 0.1 0.0 0.0 0.7 31.1 1.5 0.2 0.0 69.3 0.0 33.0 0.0 1418.0 433.8 2.2 0.0 0.0 0.0 2.8 0.0 0.4 0.0 3.6 0.0 3.3 0.3 4.6 5.9 0.0 0.0 0.0 0.1 0.5 0.3 0.1 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1569.9;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 306.4;HaCaT: 228.2;HDLM-2: 183.0;OE19: 197.4;RT4: 362.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 34.3 36.4 29.4 100.6 30.2 36.9 48.8 29.9 47.1 112.8 31.4 32.5 77.8 46.7 26.8 37.9 57.6 104.6 51.3 29.6 32.9 238.2 89.5 349.6 191.8 30.8 31.4 30.0 75.5 77.6 10.1 25.7 31.5 59.7 27.3 4.7 63.0 70.7 16.3 48.4 56.7 43.1 30.7 51.8 93.9 10.1 32.7 51.8 27.7 37.7 131.3 202.2 30.6 32.4 122.0 10.0 1.2 30.5 5.4 0.5 20.3 8.6 3.0 13.9 7.0 17.6 306.4 34.6 12.6 0.0 13.5 228.2 5.2 52.6 10.1 183.0 0.4 3.0 1.3 38.4 12.1 0.4 7.1 5.6 10.7 0.2 0.0 59.4 1.0 5.9 76.0 0.0 17.9 2.8 32.6 87.8 8.9 197.4 4.9 0.3 0.4 5.9 49.9 362.1 2.6 5.2 41.5 27.8 75.4 10.1 12.5 48.0 16.4 0.2 6.2 0.0 5.3 0.8 92.4 19.5 0.1 89.2 12.3 0.0 208.5 2.0 7.6 137.7 29.7 83.3 20.5 7.4 183.6 56.0 1.8 3.8 8.7 3.2 94.8 22.9 18.3 147.5 29.4 30.2 29.9 47.1 29.6 32.9 30.8 31.4 31.5 30.7 32.7 32.4 169.8 237.2 1569.9 59.1 127.4 24.2 280.7 363.9 30.1 1.3 45.5 41.7 26.2 358.9 258.7 367.8 4.2 19.8 8.1 9.1 84.1 225.0 25.3 67.0 86.0 124.5 9.1 3.0 2.2 142.0 39.6 53.8 106.0 42.8 32.8 2.7 14.3 115.5 256.7 0.0 2.9 18.6 101.7 177.8 259.6 22.6 73.0 350.4 80.0 15.9 360.9 22.6 5.2 1.5 1.1 84.6 16.0 6.0 155.8 112.0 153.0 523.2 261.6 6.6 19.7 4.5 22.3 12.3 56.4 41.6 18.6 23.4 29.4 17.8 40.1 340.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1078.9;Langerhans cells: 983.5;Macrophages: 652.3;monocytes: 723.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 542.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 178.1 117.8 18.9 208.8 21.8 99.8 137.0 20.5 32.0 92.1 59.6 173.8 215.4 87.3 13.4 53.1 88.9 89.4 152.6 15.3 33.9 125.6 356.4 233.3 271.5 31.6 23.5 71.0 89.4 91.8 112.5 118.7 27.9 87.8 77.1 4.1 181.0 66.3 58.7 58.5 226.0 97.9 26.2 234.4 88.2 24.6 47.2 57.1 122.3 54.6 91.3 146.3 69.0 45.4 205.4 139.8 1.1 1.1 114.2 124.2 106.5 291.0 225.4 187.4 152.3 231.6 324.6 96.5 213.9 542.1 0.5 160.1 51.4 257.5 30.2 362.1 13.6 80.3 169.0 0.8 137.3 9.0 331.0 130.9 127.8 83.1 62.4 34.8 281.3 1.1 74.0 48.7 90.0 1.1 1.3 70.6 11.5 43.5 158.2 2.9 0.4 135.7 86.3 25.5 2.7 1.7 222.4 258.4 0.8 19.5 131.9 148.4 420.5 1.4 161.8 209.0 2.0 253.7 172.0 18.2 2.8 207.9 0.4 1.2 1.5 1.6 0.6 1.4 0.4 1.1 0.6 0.4 1.1 1.4 0.7 0.8 1.6 0.5 2.9 1.8 0.3 0.7 18.9 21.8 20.5 32.0 15.3 33.9 31.6 23.5 27.9 26.2 47.2 45.4 132.1 16.0 5.3 5.9 119.8 50.3 64.5 33.8 24.5 6.7 67.4 99.6 21.7 62.9 14.1 71.7 0.0 38.2 104.8 303.6 23.5 176.0 3.5 52.9 47.7 82.2 27.1 63.3 5.3 42.4 104.8 71.5 19.4 71.3 10.8 68.4 62.8 363.0 1078.9 11.8 3.0 56.6 26.4 334.0 983.5 6.0 13.1 652.3 101.4 23.4 723.6 58.6 21.6 2.5 2.5 82.6 217.5 13.9 96.3 50.6 339.8 90.0 18.8 5.0 46.0 67.5 74.5 3.7 4.8 14.5 41.5 41.3 33.4 3.3 99.7 52.7 CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center, Cytosol" "HPA007301: AB_1847693" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.14e-4)" "unprognostic (4.21e-3)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (1.05e-1)" "prognostic favorable (8.08e-4)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (9.99e-2)" "unprognostic (5.12e-2)" 14.5 4.8 5.6 10.3 4.6 0.5 11.3 4.4 6.1 11.8 3.1 15.5 7.5 15.2 4.7 19.5 8.4 16.5 6.3 4.4 7.6 9.1 5.6 13.0 6.2 7.3 6.6 9.4 4.6 7.4 3.5 20.2 7.1 8.9 14.8 8.2 7.0 9.2 3.0 15.4 10.5 13.5 5.7 10.6 8.6 5.8 5.9 4.3 8.3 6.9 8.2 15.6 11.8 7.6 21.8 7.9 25.7 12.2 17.0 22.3 8.6 33.6 31.4 21.4 21.1 6.1 10.7 3.4 13.2 25.4 10.5 17.4 16.9 23.2 24.9 7.1 8.1 4.6 13.1 4.9 19.7 1.6 7.8 26.4 14.0 26.5 23.0 24.5 52.7 5.7 4.2 3.0 29.9 6.4 3.0 0.6 16.6 6.1 12.3 5.3 24.0 0.0 32.6 15.9 12.6 13.2 26.0 5.3 13.3 24.5 4.3 1.8 68.5 21.3 24.9 22.0 15.8 0.4 3.1 0.1 22.1 2.0 57.0 0.0 2.6 0.0 0.0 2.1 0.0 0.1 0.0 0.0 8.6 0.3 0.0 0.0 0.1 0.0 0.4 3.7 2.0 0.4 5.6 4.6 4.4 6.1 4.4 7.6 7.3 6.6 7.1 5.7 5.9 7.6 100.4 57.7 22.4 17.6 4.4 38.7 30.2 32.0 24.5 10.2 12.3 9.5 9.7 7.2 41.4 22.0 6.2 17.6 4.6 64.0 3.9 39.1 3.3 29.1 30.7 71.6 8.3 3.6 44.1 21.6 12.8 24.2 14.8 58.5 19.0 17.8 41.7 1.6 13.5 5.0 31.2 27.4 30.5 29.7 131.7 4.0 10.5 40.8 16.0 81.5 30.5 11.0 0.0 30.2 25.1 47.7 52.7 11.3 0.7 25.4 21.7 22.6 17.5 7.9 19.7 20.1 29.2 16.8 16.7 25.0 60.7 25.4 2.7 9.1 24.4 69.3 CUX2 "CDP2, CUTL2, KIAA0293" ENSG00000111249 "Cut like homeobox 2" O14529 12 111034165-111350554 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 20.6;choroid plexus: 25.7;liver: 20.4;prostate: 11.4" "Cell type enhanced" "Detected in some" "dendritic cells: 28.1;Excitatory neurons: 175.4;Hepatocytes: 50.9;Horizontal cells: 26.9;Inhibitory neurons: 72.5" "Group enriched" "Detected in some" 4 "liver cancer: 5.2;prostate cancer: 11.2" "Region enhanced" "Detected in many" "cerebral cortex: 20.6" "Immune cell enriched" "Detected in single" 70 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 70 "dendritic cells: 6.9" "Cell line enhanced" "Detected in some" "HBEC3-KT: 6.6;HDLM-2: 2.9;hTERT-HME1: 3.5;SCLC-21H: 6.5;SH-SY5Y: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (3.87e-2)" "unprognostic (6.98e-3)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (2.78e-2)" "unprognostic (1.22e-2)" "unprognostic (9.44e-2)" "unprognostic (2.33e-1)" "unprognostic (3.30e-2)" "unprognostic (7.83e-5)" "unprognostic (2.67e-1)" "unprognostic (3.54e-3)" "unprognostic (4.31e-2)" "unprognostic (9.03e-2)" "unprognostic (4.64e-2)" "unprognostic (1.90e-2)" 0.0 0.0 2.3 0.2 1.4 0.2 1.8 0.0 20.6 0.8 25.7 0.3 0.1 0.1 0.3 0.1 0.0 0.0 0.0 3.5 0.0 0.2 20.4 0.0 0.5 0.0 1.5 0.0 0.1 0.0 2.1 0.0 0.0 11.4 0.0 2.3 0.0 2.9 0.1 0.2 0.2 0.0 0.0 0.2 1.5 0.5 5.2 0.2 4.2 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 6.6 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 6.5 14.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 2.3 1.4 0.0 20.6 3.5 0.0 0.0 1.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 7.2 0.5 0.0 3.5 0.7 0.0 6.4 2.6 3.0 1.0 2.8 0.1 0.0 0.0 0.0 28.1 0.1 0.0 0.0 1.2 3.7 0.1 0.1 0.0 2.7 175.4 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 50.9 0.7 26.9 72.5 0.0 0.0 0.6 0.0 0.6 0.0 0.5 0.0 1.9 0.0 0.1 0.0 20.1 1.8 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.9 0.0 0.3 0.1 0.8 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.6 CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 323.4;Proximal enterocytes: 263.0;Suprabasal keratinocytes: 343.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 93.4;Hep G2: 63.0;NTERA-2: 109.1;RT4: 104.4" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted - unknown location" NA NA 18000 "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" 3.6 2.9 7.0 2.8 8.7 2.6 9.8 6.6 10.8 7.7 22.8 22.5 42.3 5.3 15.2 14.5 10.6 18.3 9.3 8.9 7.1 8.3 49.3 13.6 0.7 10.4 6.8 0.4 15.8 6.8 4.7 0.3 9.3 15.1 25.6 4.9 15.4 14.2 0.4 53.4 42.6 3.3 9.7 2.4 30.9 12.5 7.3 1.5 22.1 0.0 4.1 25.6 10.9 17.7 16.8 9.0 44.6 0.1 0.0 0.0 26.7 0.2 0.2 0.7 2.7 93.4 14.6 6.2 19.7 0.0 13.3 28.1 22.8 6.2 1.0 9.3 19.0 0.1 24.1 63.0 2.9 1.8 0.1 0.0 24.6 1.3 0.4 10.8 9.0 5.5 0.3 0.4 0.0 1.1 3.7 0.1 109.1 15.2 0.0 0.1 15.2 12.5 38.7 104.4 18.5 12.3 10.9 12.6 6.7 45.8 25.4 0.3 0.5 0.2 25.8 0.4 6.6 4.5 7.7 0.4 3.6 0.1 0.6 1.0 0.1 0.1 0.1 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.6 0.2 0.3 0.2 0.0 0.0 0.1 0.2 7.0 8.7 6.6 10.8 8.9 7.1 10.4 6.8 9.3 9.7 7.3 17.7 0.2 141.1 79.0 2.6 1.0 323.4 172.7 110.6 132.6 16.9 58.6 28.2 29.8 161.5 106.6 103.0 27.1 0.8 0.3 238.4 5.9 130.0 5.3 118.9 8.3 4.8 80.8 9.9 60.4 93.7 0.2 8.6 94.3 128.9 5.7 1.1 47.8 127.7 0.6 0.0 43.0 107.5 81.4 22.9 13.1 7.7 2.1 3.3 23.2 40.3 0.7 13.4 0.0 78.9 161.4 93.4 155.3 0.0 1.6 125.1 263.0 4.0 85.6 11.2 6.6 0.2 5.3 6.4 24.5 117.0 343.8 0.7 4.3 0.5 107.0 202.7 CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3435.4;Basal squamous epithelial cells: 3284.9;Breast myoepithelial cells: 1544.3;Fibroblasts: 2220.8;Glandular and luminal cells: 1201.1;Proximal tubular cells: 3662.8;Suprabasal keratinocytes: 2115.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HAP1: 61.6;hTCEpi: 79.9;RPTEC TERT1: 222.2;SuSa: 115.2;U-2 OS: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 33: Fibroblasts - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" 366.1 5.2 77.6 76.2 84.5 0.6 229.1 70.6 102.7 166.3 74.8 152.4 214.0 6.9 66.6 92.9 32.9 19.8 14.0 83.7 73.8 345.6 58.5 7.4 90.7 72.4 91.0 5.5 11.6 1.9 122.0 170.7 72.4 10.1 181.3 17.5 293.5 17.6 81.1 780.3 247.0 6.3 68.7 87.5 107.3 3.7 90.2 26.6 55.2 36.5 128.5 76.6 96.3 77.9 0.0 0.0 2.7 0.0 0.2 0.2 0.7 2.9 0.8 0.2 0.0 0.0 9.1 0.0 2.7 0.1 3.8 0.2 61.6 1.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 79.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 4.0 0.0 0.0 0.2 0.0 1.1 222.2 0.0 1.1 0.7 0.2 0.2 0.0 115.2 0.1 0.0 0.0 0.1 84.9 0.4 0.1 0.3 0.0 0.0 1.4 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 77.6 84.5 70.6 102.7 83.7 73.8 72.4 91.0 72.4 68.7 90.2 77.9 123.8 0.0 1.1 32.7 13.1 3435.4 14.4 276.9 3284.9 245.7 47.5 1544.3 4.1 0.0 5.1 283.3 0.0 35.9 6.1 0.0 563.4 0.0 0.8 45.0 140.8 45.9 0.0 0.0 1.0 0.0 25.4 2220.8 0.5 1201.1 0.0 0.0 43.5 0.2 63.6 6.7 150.8 0.0 240.1 0.9 887.9 1.3 20.8 35.3 439.4 8.4 0.0 6.7 0.0 4.5 4.2 0.1 0.0 0.4 13.3 10.6 0.0 3662.8 2.1 19.0 0.0 889.8 99.2 0.4 5.2 69.3 2115.0 77.2 43.4 0.3 0.1 9.3 CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136118149 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.1;lymphoid tissue: 549.3" "Cell type enhanced" "Detected in many" "B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" 51.8 184.5 11.8 297.9 11.4 1175.1 39.6 14.6 23.8 36.1 20.1 33.2 12.6 35.2 5.5 34.9 64.9 84.5 21.8 10.6 19.7 29.0 52.4 95.5 383.8 24.3 12.8 12.9 10.0 12.3 32.6 57.5 18.2 34.1 48.6 7.8 30.2 11.8 5.2 9.8 246.5 28.1 16.7 346.5 64.0 4.0 15.2 491.2 36.7 12.0 549.3 99.3 26.9 32.3 0.8 0.3 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 580.8 1.8 0.0 0.4 0.7 1.7 0.0 0.0 29.6 6.9 35.1 84.3 0.0 0.0 81.5 60.7 0.0 0.0 0.0 0.0 0.0 54.5 323.6 1.0 302.1 0.0 1.5 538.9 72.8 9.3 45.4 2.9 281.0 62.6 102.5 4.5 0.0 30.9 26.1 0.6 2.0 0.3 2.9 0.7 156.7 8.1 0.0 2.0 0.5 0.4 648.5 116.7 677.4 0.1 131.8 0.1 87.0 28.5 117.8 83.8 15.6 67.3 115.6 76.5 79.6 25.7 166.2 113.1 109.5 143.3 17.2 9.1 63.7 76.1 51.9 11.8 11.4 14.6 23.8 10.6 19.7 24.3 12.8 18.2 16.7 15.2 32.3 32.0 16.0 42.2 8.5 1446.9 41.0 5.7 0.3 9.6 8.6 46.1 42.2 5.2 11.5 4.4 3.7 0.0 1.5 1015.1 1.1 13.7 5.1 1.2 20.0 8.9 67.6 1.8 67.5 0.0 0.9 4.2 28.9 52.0 71.0 12.6 9.0 29.6 9.1 159.9 0.0 0.2 2.0 10.2 270.0 486.2 2.9 1.5 513.6 113.8 3.7 189.2 1.0 153.5 0.0 2.0 2.3 1.1 2.6 534.2 3.2 0.0 3.2 2.4 0.8 46.0 99.1 23.1 0.5 7.8 8.5 35.7 6.3 1436.5 4.6 1.8 4.5 CXXC4 IDAX ENSG00000168772 "CXXC finger protein 4" 4 104468308-104494901 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 16.1;retina: 7.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 48.0;Cone photoreceptor cells: 31.3;Enteroendocrine cells: 102.1;Horizontal cells: 45.4;Oligodendrocyte precursor cells: 64.3;Oligodendrocytes: 30.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.0;AN3-CA: 9.7;Karpas-707: 9.0;RPMI-8226: 5.5;SCLC-21H: 12.0;U-266/70: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036600, HPA036925" Uncertain Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" Nucleoplasm "HPA036600: AB_10673659, HPA036925: " "unprognostic (1.37e-2)" "unprognostic (1.12e-1)" "unprognostic (5.75e-2)" "unprognostic (5.86e-2)" "unprognostic (9.07e-3)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (9.69e-3)" "unprognostic (2.75e-1)" "unprognostic (2.45e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.82e-1)" "unprognostic (4.52e-3)" "unprognostic (5.69e-2)" "unprognostic (1.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.42e-3)" 0.6 1.3 4.9 0.1 3.9 0.0 1.4 3.0 16.1 0.7 0.2 1.3 1.8 0.4 1.7 0.1 2.3 0.3 1.9 4.3 10.1 0.4 0.8 0.6 0.0 5.0 6.1 1.8 3.0 0.7 4.4 0.3 4.5 0.5 0.8 7.3 2.9 0.4 0.3 0.2 1.9 0.4 4.4 0.4 1.3 1.6 11.9 0.5 2.4 0.1 0.0 0.2 0.3 4.8 0.0 0.2 7.0 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.4 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 9.0 0.0 0.0 2.7 0.0 2.5 0.1 0.1 0.0 0.0 5.5 0.0 0.1 12.0 2.2 0.0 0.6 0.0 2.8 0.3 0.0 0.0 0.0 1.5 0.0 0.1 9.7 2.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.9 3.9 3.0 16.1 4.3 10.1 5.0 6.1 4.5 4.4 11.9 4.8 12.4 0.0 6.4 10.4 0.1 0.3 1.0 0.8 1.2 48.0 8.4 5.6 15.9 2.8 2.2 0.0 31.3 0.2 0.8 0.4 0.0 0.1 0.3 13.0 0.9 2.9 102.1 0.0 23.8 3.3 0.0 1.0 0.0 0.6 0.0 1.2 1.1 2.7 0.1 45.4 27.5 6.2 0.0 0.3 0.3 0.9 0.3 0.1 1.8 0.0 0.0 13.8 1.0 64.3 30.8 1.5 1.2 10.9 0.3 0.6 10.2 1.1 12.6 26.7 0.0 15.6 0.9 0.0 4.8 0.1 0.0 0.3 0.5 0.1 2.6 0.5 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 CYB5B CYB5-M ENSG00000103018 "Cytochrome b5 type B" O43169 16 69424619-69466264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 318.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007893 Approved Approved "Endoplasmic reticulum,Centriolar satellite,Cytosol" NA NA 99000 "Cluster 44: Non-specific - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "Centriolar satellite, Cytosol" "HPA007893: AB_1847369" "unprognostic (1.13e-1)" "unprognostic (4.47e-2)" "unprognostic (9.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (2.87e-3)" "unprognostic (4.35e-3)" "unprognostic (3.87e-1)" "unprognostic (1.44e-2)" "unprognostic (1.52e-2)" "unprognostic (3.10e-1)" "prognostic favorable (6.38e-5)" "unprognostic (9.69e-3)" "unprognostic (4.66e-2)" "unprognostic (3.78e-2)" "unprognostic (1.30e-2)" 60.2 318.0 52.3 51.4 53.9 20.9 50.4 46.0 69.9 45.8 43.6 92.6 69.5 49.3 72.8 59.3 58.2 45.4 58.0 56.9 51.2 71.9 83.8 54.1 68.8 50.7 48.1 44.0 40.1 77.7 28.6 73.8 50.6 47.6 116.0 49.4 36.3 48.3 65.8 45.8 67.8 61.6 44.7 49.6 49.3 38.6 52.3 74.3 54.1 78.2 76.9 80.4 38.2 48.4 186.2 576.4 232.9 144.9 105.1 139.3 99.5 162.3 224.1 266.0 249.2 406.1 221.3 168.0 159.3 157.9 216.0 214.5 224.4 235.0 300.0 90.2 85.5 81.2 97.1 479.1 154.7 169.1 172.4 120.9 116.3 315.9 149.6 111.8 254.7 190.5 133.6 78.4 165.2 241.2 278.9 204.1 173.5 171.4 78.4 260.0 128.7 184.3 359.3 208.7 135.7 69.7 431.6 82.0 142.2 119.0 159.0 133.2 115.9 152.2 124.5 102.2 145.5 94.7 227.0 516.6 157.0 138.0 180.0 121.1 57.6 71.5 103.8 80.0 85.0 68.8 76.9 81.8 69.8 63.1 62.8 75.5 17.1 96.4 59.7 124.2 134.6 105.6 52.3 53.9 46.0 69.9 56.9 51.2 50.7 48.1 50.6 44.7 52.3 48.4 36.2 44.8 46.8 44.7 47.2 49.8 49.2 84.0 66.0 22.8 28.6 26.0 25.0 30.0 51.4 62.5 6.2 159.8 66.7 112.7 78.2 66.2 18.8 56.4 33.3 61.7 23.4 38.7 40.9 70.4 94.1 38.4 27.5 87.7 60.2 36.6 43.9 54.9 64.8 30.3 30.4 76.6 83.4 30.1 57.5 22.7 44.4 33.4 62.2 24.4 55.8 63.0 96.8 23.6 39.4 70.5 78.8 44.4 28.1 34.9 75.9 62.9 49.5 31.6 46.0 22.2 36.5 48.1 46.6 44.9 42.3 59.8 54.1 84.8 61.6 50.4 CYB5R1 "humb5R2, NQO3A2" ENSG00000159348 "Cytochrome b5 reductase 1" Q9UHQ9 1 202961873-202967275 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 605.2" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 187.2;Extravillous trophoblasts: 196.5;Syncytiotrophoblasts: 293.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 187.3;hTCEpi: 188.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010641, HPA014147" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria Cytosol "HPA010641: AB_1078600, HPA014147: AB_1847370" "unprognostic (6.36e-2)" "unprognostic (8.51e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.86e-2)" "unprognostic (4.34e-2)" "unprognostic (8.46e-2)" "unprognostic (1.28e-1)" "unprognostic (4.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.73e-2)" "unprognostic (2.33e-1)" "unprognostic (6.14e-2)" "unprognostic (2.37e-3)" "unprognostic (1.69e-1)" 38.6 57.3 37.4 23.0 38.8 19.7 43.7 41.1 40.5 49.7 57.3 35.7 19.3 41.2 131.4 61.6 68.2 27.2 154.8 38.3 48.0 64.5 50.2 44.0 25.2 45.4 49.4 41.7 45.1 82.9 46.1 66.6 55.7 41.1 21.2 34.3 56.9 40.0 605.2 123.8 25.7 37.5 39.9 39.1 92.8 50.7 41.4 40.1 40.5 308.0 38.8 52.7 45.8 43.6 34.8 21.3 18.3 37.7 166.0 37.9 178.5 68.3 63.4 43.2 38.4 17.5 39.9 21.5 56.5 68.1 24.0 187.3 14.9 58.0 28.2 31.2 37.8 12.4 24.0 20.4 59.7 10.5 29.6 61.2 188.3 47.5 25.8 36.4 28.9 25.8 37.0 37.6 157.8 40.4 13.6 9.5 12.1 31.0 40.1 21.9 87.6 45.7 41.1 40.8 15.7 19.1 38.0 124.0 57.4 39.4 57.7 23.4 28.5 49.0 20.8 18.7 38.3 34.9 44.5 10.0 53.6 16.2 37.1 24.4 56.7 46.6 27.4 42.6 36.3 23.4 30.9 28.9 37.6 35.0 41.9 29.6 46.0 32.2 29.4 25.9 34.2 52.6 37.4 38.8 41.1 40.5 38.3 48.0 45.4 49.4 55.7 39.9 41.4 43.6 33.0 22.4 29.8 10.1 15.5 187.2 38.5 89.5 42.1 21.0 46.1 41.9 119.3 37.1 60.5 29.5 29.2 171.1 15.8 10.6 7.9 38.3 5.0 58.7 17.3 30.0 19.2 30.7 8.9 48.3 196.5 28.9 31.6 34.9 28.5 13.6 32.9 44.6 63.5 10.1 11.3 10.8 105.8 45.4 29.7 8.6 29.8 39.5 64.0 8.4 20.9 65.9 11.3 11.6 8.1 72.8 11.3 31.2 12.5 25.8 16.0 38.9 75.9 35.0 13.1 49.1 30.0 23.0 4.3 40.6 157.4 293.5 19.5 27.9 14.7 48.2 CYBA p22-PHOX ENSG00000051523 "Cytochrome b-245 alpha chain" P13498 16 88643289-88651054 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" Oxidoreductase "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 742.0;lymphoid tissue: 693.1" "Cell type enhanced" "Detected in many" "dendritic cells: 1632.1;Hofbauer cells: 2171.9;Kupffer cells: 1734.2;Macrophages: 1682.8;monocytes: 1688.5;NK-cells: 1805.4;Plasma cells: 1990.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 733.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 1058.3;RPMI-8226: 1631.2;THP-1: 1231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009492 Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009492: AB_2090309" "prognostic favorable (8.19e-4)" "unprognostic (1.05e-1)" "unprognostic (8.32e-2)" "prognostic favorable (4.75e-5)" "unprognostic (2.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.88e-2)" "unprognostic (9.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.91e-1)" "unprognostic (5.22e-2)" "unprognostic (2.57e-2)" "unprognostic (1.63e-2)" 149.9 68.0 40.3 344.4 41.8 742.0 93.3 46.0 58.0 81.9 62.4 200.9 196.6 60.8 38.5 80.9 95.4 122.5 93.2 38.6 55.0 187.7 71.5 234.6 333.8 73.8 49.3 40.0 108.6 13.4 40.6 54.9 64.1 75.2 79.9 1.8 116.7 26.6 41.8 39.4 245.3 51.3 65.4 693.1 236.0 10.4 62.4 87.1 136.5 19.9 192.8 144.6 74.1 92.2 2.5 663.0 2.6 1.5 1.3 0.4 329.5 155.7 77.3 39.3 24.1 447.2 819.6 510.5 420.7 56.4 0.0 250.5 21.4 0.9 5.8 146.1 564.1 99.0 217.7 694.9 75.7 156.3 397.6 80.7 0.0 1.6 0.3 1.9 23.9 103.6 278.5 567.5 3.2 1058.3 147.9 822.3 106.2 248.7 1.5 437.9 1.6 1631.2 324.9 490.9 84.2 76.5 482.7 78.8 138.5 60.8 1.4 1231.3 129.8 1.5 6.1 1.8 2.2 362.9 459.9 543.6 195.5 464.9 53.4 120.2 103.8 733.7 76.7 150.1 55.8 109.8 36.7 70.4 107.0 110.7 28.9 36.7 192.3 36.4 143.3 196.3 41.2 47.3 40.3 41.8 46.0 58.0 38.6 55.0 73.8 49.3 64.1 65.4 62.4 92.2 157.8 16.0 12.4 0.0 1290.9 119.4 233.4 420.8 53.5 0.4 131.7 133.2 12.8 368.9 487.1 285.1 2.1 45.3 1632.1 807.2 127.2 636.8 4.2 219.5 137.5 137.1 230.5 162.7 0.2 155.3 299.0 184.8 285.4 312.5 279.0 104.3 317.0 23.9 2171.9 0.0 0.2 540.3 233.9 1734.2 1370.8 14.0 50.1 1682.8 1152.6 32.8 1688.5 1.6 1805.4 1.0 0.2 682.8 1045.8 21.4 1990.6 191.8 390.4 1057.4 529.7 2.7 59.2 44.0 164.3 0.9 15.6 75.2 85.7 118.2 838.6 20.5 805.2 436.9 CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 89.7;intestine: 83.4;liver: 146.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 91.4;Cytotrophoblasts: 116.2;Hepatocytes: 58.3;Oligodendrocytes: 68.5;Proximal enterocytes: 134.6;Syncytiotrophoblasts: 240.9" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "OE19: 16.9;RT4: 62.3;SK-BR-3: 16.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" 1.2 0.4 18.3 1.2 22.1 0.1 9.3 23.6 19.1 2.3 8.4 19.0 34.1 1.0 0.8 13.1 0.9 2.0 89.7 14.7 19.4 3.0 146.2 1.4 0.2 20.7 20.7 0.0 2.2 0.0 0.9 22.3 18.9 3.3 21.3 3.5 14.5 0.7 25.3 8.9 83.4 1.8 20.2 0.1 4.7 0.6 28.0 0.5 0.1 6.4 0.7 5.8 3.6 21.8 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.7 0.1 1.2 0.3 2.8 0.0 0.8 0.0 3.5 0.9 0.0 0.9 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.1 0.5 0.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 3.2 0.0 0.0 1.5 16.9 2.6 0.0 6.3 0.0 3.4 62.3 0.9 3.8 0.1 16.4 0.6 0.1 4.1 0.0 0.0 2.2 2.5 0.0 0.9 1.9 0.1 0.0 0.5 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.8 0.3 0.2 0.0 0.4 2.9 2.6 0.0 0.4 0.0 0.6 0.0 0.4 18.3 22.1 23.6 19.1 14.7 19.4 20.7 20.7 18.9 20.2 28.0 21.8 0.0 3.2 4.1 35.6 0.7 0.4 1.7 5.5 7.4 0.0 5.1 3.0 91.4 11.5 28.9 0.0 0.0 116.2 0.1 26.4 0.0 9.5 22.7 3.1 1.7 1.3 9.0 0.0 0.1 0.9 9.3 2.3 4.1 7.7 0.0 1.5 0.0 58.3 7.0 0.0 0.4 18.7 6.1 0.8 0.3 23.3 0.0 0.2 0.0 1.9 0.6 12.5 0.0 29.7 68.5 2.0 18.1 0.0 0.3 1.5 134.6 2.5 20.1 0.9 0.0 0.7 1.0 0.3 0.2 7.3 2.3 240.9 0.2 0.4 24.1 2.1 CYP2W1 "FLJ20359, MGC34287" ENSG00000073067 "Cytochrome P450 family 2 subfamily W member 1" Q8TAV3 7 983181-989640 "Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 19.1;intestine: 6.1;skin 1: 10.5" "Cell type enriched" "Detected in some" 7 "Enteroendocrine cells: 98.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 25.3;stomach cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 13.5;Hep G2: 49.8" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.09e-3)" "unprognostic (1.94e-2)" "unprognostic (2.75e-2)" "unprognostic (1.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.22e-1)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (6.26e-2)" "unprognostic (2.72e-5)" "unprognostic (7.52e-2)" "unprognostic (1.34e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.85e-4)" 0.1 19.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.4 0.0 0.9 6.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.3 1.0 0.1 2.1 0.5 0.2 0.3 0.2 0.0 10.5 1.0 0.0 0.0 0.4 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.0 0.2 49.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 2.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.6 4.3 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 4.0 2.3 1.5 0.0 0.6 0.0 0.0 0.5 0.0 2.6 0.0 0.0 1.1 0.0 3.7 0.0 0.1 0.1 0.1 0.0 0.3 98.5 0.0 0.0 0.9 0.6 10.2 0.0 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 13.6 0.0 0.0 0.9 0.0 1.8 0.3 0.0 0.0 0.1 10.5 0.0 0.0 0.0 0.1 3.3 0.0 0.1 1.2 1.1 0.0 3.3 0.6 0.0 0.8 0.3 0.2 0.1 0.0 4.4 1.9 0.2 4.4 11.4 3.7 CYP39A1 ENSG00000146233 "Cytochrome P450 family 39 subfamily A member 1" Q9NYL5 6 46549580-46652830 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 99.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 62.9;Late spermatids: 20.1" "Cancer enhanced" "Detected in many" "prostate cancer: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 6.5;hTCEpi: 13.6;OE19: 6.1;SiHa: 8.4;U-698: 10.4" "Region enhanced" "Detected in all" "olfactory bulb: 22.9" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.33e-1)" "unprognostic (1.62e-2)" "unprognostic (8.46e-3)" "unprognostic (5.89e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (4.99e-2)" "unprognostic (7.33e-2)" "unprognostic (6.11e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.54e-1)" "unprognostic (5.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" 3.0 2.5 2.1 1.0 2.7 0.0 5.4 3.5 2.9 3.7 5.3 2.7 0.8 3.6 21.0 3.3 4.1 6.3 3.9 2.0 2.1 5.7 99.2 3.3 0.5 2.3 2.3 11.5 5.7 15.3 2.9 0.4 2.1 14.8 3.6 4.1 23.5 2.6 0.6 15.9 1.6 2.4 2.4 0.7 2.8 4.2 2.4 0.4 6.1 1.2 1.4 2.7 3.0 2.9 0.2 0.4 0.3 1.8 0.3 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.5 6.5 4.4 0.0 0.9 1.7 0.8 1.4 0.0 0.0 2.8 0.0 1.7 1.8 4.0 0.0 0.0 0.5 13.6 0.0 1.6 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 1.5 0.5 1.1 0.1 2.9 4.0 0.7 0.0 8.4 0.0 0.2 0.4 1.5 0.0 0.0 0.2 0.9 0.0 0.1 0.0 0.0 10.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.7 3.5 2.9 2.0 2.1 2.3 2.3 2.1 2.4 2.4 2.9 3.3 16.0 1.5 3.9 0.2 4.0 8.8 2.7 2.8 1.4 4.6 6.5 5.8 10.0 4.3 3.7 2.1 0.0 0.0 1.1 5.9 2.9 12.7 4.4 1.0 3.5 0.0 5.3 3.2 0.4 0.9 4.5 1.5 3.1 0.0 2.7 1.1 62.9 0.2 0.0 2.0 4.0 10.2 2.5 0.9 20.1 6.2 0.3 3.6 8.4 0.0 8.6 0.0 1.0 7.2 0.5 2.7 9.4 0.0 7.9 0.3 5.3 7.2 1.5 0.0 1.9 2.3 0.7 0.8 2.6 15.3 0.0 0.2 6.3 2.5 8.1 CYP4F2 ENSG00000186115 "Cytochrome P450 family 4 subfamily F member 2" P78329 19 15878023-15898077 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 80.2;kidney: 40.9;liver: 166.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 139.7;Proximal enterocytes: 204.6" "Cancer enriched" "Detected in some" 9 "liver cancer: 29.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 19 "basophil: 8.1" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.1" "Cell line enriched" "Detected in single" 4 "Hep G2: 3.8" "Low region specificity" "Detected in all" "HPA014048, HPA017265, HPA058960" Supported "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "HPA014048: AB_1847452, HPA017265: AB_1847451, HPA058960: AB_2683862" "unprognostic (7.46e-3)" "unprognostic (3.58e-1)" "unprognostic (3.01e-1)" "unprognostic (9.39e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-2)" "unprognostic (4.55e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (8.69e-4)" "unprognostic (3.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.79e-3)" 0.0 0.0 0.1 0.1 0.1 1.1 0.2 0.1 0.3 0.1 0.5 2.2 79.9 0.0 25.8 0.2 0.0 3.3 0.0 0.2 0.1 40.9 166.7 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.1 6.6 0.9 0.0 0.0 0.1 0.0 0.8 80.2 0.0 0.3 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.0 12.3 1.9 0.1 5.8 0.0 0.0 0.1 1.8 5.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 1.4 139.7 0.0 0.0 0.0 8.9 0.0 3.8 0.0 18.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.5 204.6 37.7 0.0 0.0 0.0 0.0 0.7 0.1 0.4 0.0 0.1 0.0 0.2 0.1 5.6 0.2 CYP4F22 FLJ39501 ENSG00000171954 "Cytochrome P450 family 4 subfamily F member 22" Q6NT55 19 15508525-15552317 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;skin 1: 58.6;vagina: 22.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.8;Breast myoepithelial cells: 5.5;granulocytes: 7.0;Prostatic glandular cells: 4.0;Suprabasal keratinocytes: 3.0" "Group enriched" "Detected in many" 7 "breast cancer: 4.5;head and neck cancer: 5.7;liver cancer: 8.5;melanoma: 4.5;urothelial cancer: 13.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "intermediate monocyte: 6.1;MAIT T-cell: 4.3;non-classical monocyte: 14.1" "Group enriched" "Detected in many" 8 "monocytes: 14.1;T-cells: 4.3" "Cell line enhanced" "Detected in some" "MCF7: 1.7;T-47d: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" "HPA058960: AB_2683862" "unprognostic (2.32e-3)" "unprognostic (1.17e-2)" "unprognostic (6.81e-2)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (7.02e-2)" "unprognostic (1.30e-1)" "unprognostic (2.43e-1)" "unprognostic (3.33e-1)" "unprognostic (1.89e-2)" "unprognostic (9.33e-2)" "unprognostic (3.00e-2)" "unprognostic (2.21e-5)" "unprognostic (8.10e-2)" "unprognostic (3.16e-1)" "unprognostic (7.25e-3)" "unprognostic (2.03e-2)" 1.3 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 10.5 0.0 0.0 0.2 0.3 0.0 18.8 0.1 0.1 0.0 0.0 0.0 0.0 7.0 0.3 0.3 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 3.2 6.4 0.2 58.6 0.1 0.0 0.0 0.3 1.4 1.0 0.0 0.1 0.0 0.0 1.7 6.3 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 6.1 4.3 0.0 0.5 1.5 0.2 0.0 0.0 0.4 0.0 1.1 14.1 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 8.8 5.5 0.4 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.1 0.0 0.0 7.0 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.4 0.0 0.3 0.0 0.0 0.5 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.8 0.0 3.0 0.0 1.8 0.0 0.0 0.3 CYP4F8 ENSG00000186526 "Cytochrome P450 family 4 subfamily F member 8" P98187 19 15615218-15630639 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "seminal vesicle: 215.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.2;Breast glandular cells: 1.7;granulocytes: 1.3;NK-cells: 1.0;Prostatic glandular cells: 1.3;Skeletal myocytes: 1.7;Urothelial cells: 2.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 10.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-BR-3: 1.1" "Low region specificity" "Detected in all" HPA058960 Approved NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA058960: AB_2683862" "unprognostic (1.70e-2)" "unprognostic (5.46e-3)" "unprognostic (3.21e-2)" "unprognostic (3.97e-6)" "unprognostic (3.51e-3)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (8.25e-2)" "unprognostic (1.15e-2)" "unprognostic (1.02e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.2 215.6 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.4 1.7 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.7 0.0 1.7 0.2 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.3 2.5 CYS1 ENSG00000205795 "Cystin 1" Q717R9 2 10056780-10080944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 124.6;pancreas: 33.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 32.9;Collecting duct cells: 51.5;Distal tubular cells: 70.5;Muller glia cells: 48.0;Proximal tubular cells: 54.1" "Cancer enhanced" "Detected in many" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "RPTEC TERT1: 111.5" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.48e-2)" "unprognostic (8.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.00e-2)" "unprognostic (2.80e-1)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (1.94e-2)" "unprognostic (9.53e-2)" "unprognostic (7.05e-2)" "unprognostic (7.03e-2)" "prognostic favorable (1.27e-5)" "unprognostic (2.19e-3)" "unprognostic (1.47e-1)" "unprognostic (8.93e-2)" "unprognostic (1.20e-2)" 3.1 1.6 6.0 1.2 5.7 0.0 1.9 5.3 7.8 8.4 15.5 11.7 2.5 7.8 3.6 3.9 6.3 9.1 6.1 5.5 5.5 124.6 1.0 6.1 1.1 6.9 6.0 12.4 33.6 1.7 7.2 0.1 5.6 4.9 1.8 2.2 2.9 7.2 1.0 1.5 3.4 5.9 6.4 2.9 3.9 1.0 5.2 0.5 5.6 2.1 2.1 3.5 6.6 5.9 0.0 0.3 0.0 0.0 0.5 2.6 0.1 0.4 1.6 0.2 0.1 0.2 0.0 0.0 0.4 4.4 0.9 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 111.5 0.0 0.0 0.5 0.4 0.3 0.0 1.3 2.0 0.2 0.0 6.0 3.2 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.7 5.3 7.8 5.5 5.5 6.9 6.0 5.6 6.4 5.2 5.9 0.9 6.4 1.1 1.0 1.0 0.5 0.1 0.6 0.0 10.3 0.5 5.5 7.3 32.9 0.0 51.5 0.0 0.0 0.2 0.0 70.5 7.0 0.1 0.3 0.9 0.6 0.0 0.0 2.9 1.1 0.6 8.8 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 0.0 3.4 1.0 0.0 2.8 0.0 48.0 0.0 3.0 0.6 0.4 0.0 4.5 0.1 0.3 0.0 54.1 0.0 1.9 0.0 0.5 3.9 0.0 1.4 0.0 0.1 0.0 0.3 0.1 0.0 0.1 CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Group enriched" "Detected in some" 10 "Pancreatic endocrine cells: 58.0;Squamous epithelial cells: 66.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 25.1;CAPAN-2: 28.9;HaCaT: 33.3;HeLa: 30.6;MCF7: 49.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 0.6 1.1 0.6 0.2 0.4 0.4 1.5 0.3 1.6 43.1 0.0 0.6 0.4 0.5 0.4 239.5 1.8 0.7 0.9 0.8 0.8 3.7 1.7 1.1 0.7 1.4 1.3 0.3 1.5 0.6 7.3 0.3 0.6 2.6 0.1 0.6 29.9 0.5 0.4 34.4 0.8 0.0 1.0 0.7 2.0 4.1 0.9 0.3 2.4 0.0 14.3 1.2 57.7 0.5 25.1 2.4 1.8 3.9 0.0 0.1 5.3 0.4 0.4 0.5 0.2 1.3 28.9 1.3 1.2 0.3 0.7 33.3 0.5 7.0 0.0 2.7 1.8 0.3 30.6 16.8 0.9 0.2 1.4 0.4 3.5 0.9 0.2 1.3 0.3 1.4 0.6 3.1 1.6 49.5 0.7 1.0 0.7 4.8 3.0 2.4 2.8 3.5 0.6 1.6 0.4 1.8 4.5 3.5 0.9 1.5 7.7 0.4 1.0 1.1 0.9 3.2 0.6 1.9 1.7 1.2 1.4 1.3 1.4 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.6 0.4 0.3 1.6 0.8 0.8 1.4 1.3 0.6 1.0 0.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.5 0.4 1.5 2.5 5.5 0.0 0.6 0.1 0.4 0.0 4.6 0.5 2.1 0.2 0.3 0.0 0.0 0.3 5.8 0.2 0.1 3.1 1.7 0.0 0.6 0.7 0.8 0.2 0.0 0.3 0.6 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 58.0 1.1 0.4 0.1 0.2 1.6 0.9 0.0 0.6 0.0 0.3 0.3 3.0 1.1 66.0 0.0 0.0 0.1 0.9 0.5 1.7 CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 200.0;Endothelial cells: 150.0;Hepatic stellate cells: 79.9;Microglial cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cell line enhanced" "Detected in some" "AF22: 14.1;NTERA-2: 39.2;PC-3: 11.0;RH-30: 16.6;SCLC-21H: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" 36.4 46.4 9.7 8.1 9.0 7.8 30.2 8.7 11.4 16.4 8.4 8.4 6.1 19.2 8.1 9.0 12.9 16.1 22.3 8.1 9.4 12.7 4.8 23.7 6.0 9.9 10.5 4.5 5.5 15.5 3.8 36.3 10.6 9.5 6.6 0.9 6.8 11.4 15.1 8.2 9.6 23.6 9.6 32.5 7.7 1.9 10.8 6.0 14.1 31.8 4.6 12.6 9.5 9.4 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.1 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.5 0.0 0.4 0.0 5.6 0.0 0.0 0.0 2.6 0.0 0.0 0.1 39.2 0.0 11.0 0.0 16.6 0.0 1.7 0.0 33.7 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 31.4 0.0 0.1 9.7 9.0 8.7 11.4 8.1 9.4 9.9 10.5 10.6 9.6 10.8 9.4 200.0 0.0 0.6 1.6 1.5 11.7 2.0 10.2 27.3 0.1 14.9 15.0 6.7 0.0 1.7 14.7 0.0 0.1 14.9 0.0 3.9 0.0 0.7 0.4 6.9 150.0 0.0 11.1 1.6 0.0 0.2 8.3 0.0 0.4 0.0 3.7 79.9 0.4 0.3 0.0 4.6 0.0 2.0 3.2 8.0 1.5 2.1 1.4 7.2 58.1 0.7 0.5 0.0 0.0 0.7 0.1 0.0 0.0 2.5 1.1 0.0 6.8 1.1 0.3 0.0 13.3 4.4 0.2 1.3 4.9 5.4 0.3 1.5 0.4 0.0 0.7 DAAM1 KIAA0666 ENSG00000100592 "Dishevelled associated activator of morphogenesis 1" Q9Y4D1 14 59188646-59371405 "Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 467.3;Suprabasal keratinocytes: 332.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026605, HPA064789" Uncertain Approved "Plasma membrane,Cytosol" NA NA 9700 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA026605: AB_1847464, HPA064789: AB_2685352" "unprognostic (2.81e-1)" "unprognostic (9.70e-2)" "unprognostic (3.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.32e-1)" "unprognostic (1.84e-1)" "unprognostic (1.76e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.01e-2)" "unprognostic (3.29e-1)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" 14.5 6.2 13.0 6.8 13.6 5.4 10.4 12.6 12.8 13.6 22.8 13.5 4.8 13.5 5.6 19.0 7.7 5.9 19.3 11.8 14.8 6.9 12.6 10.5 11.1 7.9 8.1 8.0 9.3 20.6 5.3 9.1 8.3 11.9 8.5 24.9 9.4 11.0 5.6 30.9 7.2 10.9 7.8 13.1 7.0 6.9 11.2 4.8 7.4 4.7 15.6 9.5 15.1 10.7 18.2 1.9 13.1 3.5 7.8 5.8 17.1 2.5 2.3 4.7 4.8 9.4 16.6 20.4 4.4 5.6 9.6 39.7 11.8 10.0 4.0 9.0 4.1 6.8 4.8 11.8 4.8 7.9 3.8 3.9 10.6 3.9 4.7 10.8 11.3 10.2 11.9 9.9 2.8 17.0 6.9 4.9 7.5 12.9 5.6 6.3 11.1 2.0 6.8 13.5 20.3 4.8 15.8 23.1 16.1 8.7 30.5 2.1 10.8 3.9 7.4 8.4 2.2 2.2 2.7 22.1 5.0 1.5 8.7 7.7 2.0 2.6 2.3 2.4 3.0 10.8 3.0 2.3 2.2 4.6 2.4 2.6 2.8 6.7 3.5 18.3 4.0 1.9 13.0 13.6 12.6 12.8 11.8 14.8 7.9 8.1 8.3 7.8 11.2 10.7 62.2 35.3 27.0 160.6 37.8 467.3 172.4 128.6 30.7 110.7 56.8 40.6 149.3 38.6 82.3 29.5 308.6 33.0 66.9 47.0 23.5 63.8 40.0 68.4 142.9 71.9 87.7 140.0 143.7 93.1 27.6 67.3 21.9 54.6 26.0 155.2 102.4 47.2 32.8 195.2 202.0 56.7 73.2 16.3 55.8 16.6 60.3 36.1 90.7 66.5 25.2 96.5 16.5 74.9 24.3 191.4 45.1 74.1 30.8 104.2 24.7 12.8 102.4 168.7 32.9 84.6 66.3 51.3 46.3 52.8 332.0 34.2 25.1 25.1 38.1 84.2 DAB1 ENSG00000173406 "DAB adaptor protein 1" O75553 1 56994778-58546734 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.8;intestine: 22.3;seminal vesicle: 10.0" "Group enriched" "Detected in some" 8 "Excitatory neurons: 460.3;Inhibitory neurons: 1170.3;Oligodendrocyte precursor cells: 814.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 2.1" "Lineage enhanced" "Detected in single" "T-cells: 2.1" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 54.0;HeLa: 18.6;NTERA-2: 23.4;RT4: 32.0;WM-115: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032329, HPA052033, HPA067495" Enhanced Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "CAB032329: AB_638973, HPA052033: AB_2681703, HPA067495: AB_2685852" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (8.54e-2)" "unprognostic (2.09e-4)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (7.30e-4)" "unprognostic (3.90e-1)" "unprognostic (3.07e-2)" "unprognostic (1.47e-2)" "unprognostic (2.06e-3)" "unprognostic (1.27e-1)" "unprognostic (2.00e-3)" "unprognostic (1.78e-1)" "unprognostic (2.01e-1)" "unprognostic (1.44e-2)" "unprognostic (5.67e-2)" 2.0 1.7 4.3 0.4 5.3 0.0 0.3 16.8 8.8 1.6 0.0 0.8 15.8 0.5 0.4 0.6 1.6 0.7 1.8 10.6 5.4 0.3 7.7 0.4 0.2 2.1 3.9 1.2 0.4 0.0 0.2 0.0 2.0 3.9 0.3 5.4 0.9 10.0 0.1 0.1 22.3 0.3 2.3 0.2 1.0 0.4 5.1 0.1 0.3 0.1 0.1 1.2 0.9 1.9 0.0 0.0 10.6 0.0 0.1 0.2 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 54.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.8 0.0 0.0 0.0 0.0 2.0 0.1 23.4 0.0 0.0 6.0 0.0 0.2 0.0 32.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.6 0.1 0.0 2.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 4.3 5.3 16.8 8.8 10.6 5.4 2.1 3.9 2.0 2.3 5.1 1.9 0.7 0.0 0.0 30.0 0.1 0.0 0.1 0.1 0.0 23.7 0.1 0.3 3.2 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 8.6 8.2 0.6 0.3 0.0 0.0 460.3 0.0 0.0 0.4 4.6 12.8 0.0 0.0 0.7 5.1 0.1 21.9 1170.3 1.9 6.1 0.3 0.0 4.7 3.4 0.1 0.0 22.5 0.0 1.0 1.0 814.8 26.5 0.0 0.0 2.6 0.0 0.1 101.1 0.2 0.0 0.8 0.0 0.1 0.9 0.2 0.5 0.0 0.0 0.7 0.6 0.0 2.1 0.0 DACH1 DACH ENSG00000276644 "Dachshund family transcription factor 1" Q9UI36 13 71437966-71867204 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Excitatory neurons: 77.0;Horizontal cells: 87.5;Late spermatids: 103.7;Microglial cells: 143.4;Muller glia cells: 143.8;Spermatocytes: 58.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 4.2;eosinophil: 8.4;NK-cell: 4.2;plasmacytoid DC: 6.4" "Group enriched" "Detected in many" 33 "dendritic cells: 6.4;granulocytes: 8.4;NK-cells: 4.2" "Cell line enhanced" "Detected in some" "AF22: 14.2;HAP1: 22.5;HEK 293: 16.8;HL-60: 37.9;NB-4: 16.7;SCLC-21H: 36.9;SH-SY5Y: 29.5;THP-1: 26.9" "Region enriched" "Detected in all" 5 "basal ganglia: 38.8" "Region enriched" "Detected in all" 5 "basal ganglia: 34.2" "HPA012672, HPA012938, HPA073222" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear speckles" "HPA012672: AB_1847466, HPA012938: , HPA073222: " "unprognostic (3.16e-1)" "unprognostic (5.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.36e-1)" "unprognostic (4.21e-2)" "unprognostic (5.63e-2)" "unprognostic (2.22e-2)" "unprognostic (8.08e-3)" "unprognostic (2.12e-2)" "unprognostic (2.50e-1)" "unprognostic (3.04e-3)" "unprognostic (4.37e-1)" "unprognostic (2.18e-2)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (5.17e-2)" 4.4 11.1 2.3 1.2 14.0 6.0 4.0 1.6 2.9 9.7 0.3 3.1 5.2 3.8 1.3 0.9 2.8 7.2 2.2 1.0 4.6 8.9 2.0 5.9 0.5 7.0 9.3 0.5 1.9 6.6 3.5 6.9 5.9 7.0 3.3 16.7 2.0 2.3 1.9 1.8 6.7 2.0 2.6 5.4 1.9 6.3 4.3 3.5 0.2 1.2 0.4 2.0 2.7 2.4 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 22.5 0.0 0.0 0.0 16.8 0.2 0.0 0.0 0.4 37.9 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.9 16.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 36.9 29.5 0.0 0.0 0.0 0.1 0.9 26.9 0.0 0.4 0.3 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.2 4.2 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 4.2 0.0 6.4 0.0 0.1 2.3 14.0 1.6 2.9 1.0 4.6 7.0 9.3 5.9 2.6 4.3 2.4 36.4 0.0 0.6 15.7 0.5 1.7 3.6 0.0 0.0 15.4 19.4 9.3 2.1 1.5 0.0 7.3 4.2 0.0 12.5 0.9 5.9 1.0 88.5 5.0 4.7 34.2 34.1 2.5 77.0 0.0 0.0 4.6 1.1 3.2 5.1 0.3 2.9 0.0 0.2 87.5 28.2 21.4 0.0 1.2 1.2 103.7 3.4 2.5 0.0 143.4 1.1 143.8 0.0 6.6 3.9 0.6 0.3 1.9 0.0 5.8 3.5 6.9 0.7 6.9 13.1 1.5 4.3 58.8 10.2 0.2 1.3 0.0 1.0 1.3 12.6 2.7 DACT2 "bA503C24.7, C6orf116, DAPPER2" ENSG00000164488 "Dishevelled binding antagonist of beta catenin 2" Q5SW24 6 168292830-168319777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.4;placenta: 12.9" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 58.2;Syncytiotrophoblasts: 216.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 14.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.2;CACO-2: 2.7;hTCEpi: 1.8;NTERA-2: 2.2;OE19: 11.2;SCLC-21H: 2.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "basal ganglia: 16.9;cerebral cortex: 21.4;hippocampal formation: 16.8" HPA030251 Enhanced Supported NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA030251: AB_10611108" "unprognostic (5.22e-6)" "unprognostic (3.13e-2)" "unprognostic (1.04e-2)" "prognostic favorable (1.07e-5)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (1.64e-2)" "unprognostic (1.08e-1)" "unprognostic (4.04e-1)" "unprognostic (1.31e-1)" "unprognostic (7.05e-3)" "unprognostic (2.48e-1)" "prognostic favorable (5.76e-5)" "unprognostic (1.51e-2)" "unprognostic (1.66e-2)" "unprognostic (2.03e-4)" "unprognostic (4.23e-2)" 2.3 3.3 3.7 0.4 19.4 0.0 0.6 2.9 6.2 1.7 1.4 1.0 0.8 2.7 0.1 1.5 1.7 0.4 5.2 2.7 2.7 3.6 5.8 1.6 0.4 4.1 3.5 0.1 2.9 0.0 0.6 12.9 4.6 7.3 0.3 5.8 6.5 0.4 0.2 5.7 0.6 0.2 2.8 0.0 0.7 1.0 4.1 1.9 0.3 0.0 0.6 1.1 1.2 3.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 11.2 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 19.4 2.9 6.2 2.7 2.7 4.1 3.5 4.6 2.8 4.1 3.0 0.0 0.0 2.0 0.0 0.0 3.1 1.9 0.8 0.0 10.7 0.1 3.0 0.6 1.5 1.3 1.8 0.0 58.2 0.0 0.1 0.0 1.3 0.0 11.8 0.5 0.7 5.3 0.0 0.1 0.2 6.1 3.4 0.0 11.0 0.0 3.3 0.0 0.3 5.3 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.1 3.6 6.5 0.0 26.3 0.0 0.0 0.1 0.3 1.2 0.0 0.0 1.1 0.0 5.7 0.0 0.9 0.0 0.5 0.1 0.0 0.3 0.0 1.4 216.3 0.2 0.0 1.9 0.1 DAPP1 BAM32 ENSG00000070190 "Dual adaptor of phosphotyrosine and 3-phosphoinositides 1" Q9UN19 4 99816827-99870190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.2;lymphoid tissue: 38.5" "Cell type enhanced" "Detected in many" "B-cells: 92.0;Langerhans cells: 188.5;monocytes: 235.5;Respiratory ciliated cells: 88.6;Urothelial cells: 221.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 61.2;RPMI-8226: 70.2;SK-BR-3: 30.6;U-698: 46.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB033822, HPA046074" Approved NA NA 56000 "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "CAB033822: AB_2245677, HPA046074: AB_2679525" "unprognostic (9.30e-2)" "unprognostic (1.36e-1)" "unprognostic (1.77e-2)" "unprognostic (9.96e-2)" "unprognostic (3.48e-1)" "unprognostic (1.14e-1)" "unprognostic (1.68e-1)" "unprognostic (9.09e-2)" "unprognostic (4.71e-1)" "unprognostic (5.13e-2)" "unprognostic (4.01e-3)" "unprognostic (2.24e-1)" "unprognostic (8.45e-5)" "unprognostic (2.88e-1)" "unprognostic (3.91e-2)" "unprognostic (9.32e-2)" "unprognostic (4.60e-2)" 1.6 1.0 0.5 22.6 0.9 15.5 3.7 0.4 0.5 6.9 0.6 3.1 2.1 8.4 1.0 29.2 5.2 11.9 0.5 0.5 0.6 0.7 1.5 6.3 34.6 1.0 1.0 0.4 0.4 0.2 0.2 6.8 1.1 2.8 3.2 0.1 8.6 0.8 0.9 13.7 6.3 13.5 0.8 16.6 6.5 0.4 0.7 10.2 0.6 1.3 38.5 14.9 12.9 1.5 22.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 22.5 23.8 0.3 0.0 0.1 12.8 0.0 25.3 0.0 61.2 0.0 24.3 0.0 0.0 0.0 9.4 1.0 0.0 11.3 0.0 7.5 0.0 0.0 1.0 1.2 21.7 0.0 0.2 0.1 6.7 0.0 0.0 0.4 0.1 0.1 70.2 4.6 16.3 0.1 0.0 0.0 30.6 0.0 0.2 0.4 10.1 0.0 0.0 0.4 0.0 0.1 8.3 3.2 46.4 0.1 6.5 0.0 25.0 70.2 71.0 2.3 62.6 2.5 90.9 11.4 4.0 75.9 98.7 12.5 4.5 138.1 17.8 57.3 32.4 25.2 65.3 0.5 0.9 0.4 0.5 0.5 0.6 1.0 1.0 1.1 0.8 0.7 1.5 0.3 3.2 3.0 0.0 92.0 61.8 30.2 51.4 16.5 0.1 10.1 5.0 0.8 2.8 43.2 9.2 0.0 2.6 13.3 8.4 0.0 6.2 0.3 37.1 0.8 1.2 1.2 9.4 0.4 3.1 14.1 1.4 14.8 9.0 8.2 0.2 0.7 0.7 25.1 0.0 0.1 1.8 22.4 32.0 188.5 0.9 0.0 86.0 12.4 5.6 235.5 0.0 7.2 0.0 0.1 18.9 17.6 0.0 60.2 24.3 0.2 0.1 88.6 0.2 0.0 0.9 4.2 0.2 0.5 40.4 70.3 3.4 17.2 0.1 2.2 221.2 DBP DABP ENSG00000105516 "D-box binding PAR bZIP transcription factor" Q10586 19 48630030-48637379 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 318.3;Horizontal cells: 215.4;Muller glia cells: 194.2;Rod photoreceptor cells: 108.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 61.7;NB-4: 235.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.49e-1)" "unprognostic (3.68e-3)" "unprognostic (2.16e-3)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "prognostic favorable (5.49e-4)" "unprognostic (2.00e-1)" "prognostic favorable (1.16e-5)" "unprognostic (3.32e-2)" "unprognostic (2.39e-1)" "unprognostic (4.24e-3)" "unprognostic (4.75e-2)" "prognostic favorable (2.41e-5)" "unprognostic (2.23e-1)" "unprognostic (2.52e-1)" "unprognostic (1.46e-2)" "unprognostic (3.61e-2)" 12.4 53.0 22.5 6.6 34.6 7.5 12.6 35.7 32.9 12.9 9.7 18.7 19.2 13.2 7.2 21.1 11.6 6.0 18.3 21.9 23.4 17.9 24.7 9.8 14.6 21.3 24.5 33.5 14.0 15.6 34.9 2.8 18.6 16.8 3.8 32.6 42.2 13.8 57.1 58.1 15.5 4.5 23.5 19.1 16.4 16.4 29.0 13.6 34.4 7.7 8.4 8.8 16.3 20.5 4.3 7.3 3.6 17.6 2.6 3.4 3.8 1.0 9.8 3.0 7.4 4.6 39.7 8.5 4.8 4.8 3.6 9.8 12.6 2.5 2.5 8.9 6.0 17.2 6.1 2.4 12.9 10.6 12.5 12.1 2.3 0.5 2.0 21.1 0.6 17.9 1.3 61.7 2.7 5.9 32.8 235.3 2.5 11.3 4.9 15.8 2.9 22.2 1.5 1.3 11.7 14.7 5.5 26.5 15.6 1.6 4.8 10.5 1.1 6.5 17.8 3.4 1.9 28.4 50.7 15.6 3.1 15.0 3.9 3.3 3.0 4.9 1.9 3.5 3.9 2.7 3.2 1.6 4.1 1.7 2.5 3.1 0.1 0.7 1.9 3.5 3.7 1.1 22.5 34.6 35.7 32.9 21.9 23.4 21.3 24.5 18.6 23.5 29.0 20.5 14.1 12.8 6.2 9.4 21.7 21.9 15.3 3.1 52.3 318.3 17.2 23.5 4.7 12.8 3.2 7.3 87.6 5.2 15.9 8.0 45.0 5.8 1.4 9.0 25.4 10.8 1.8 6.9 4.2 5.6 1.9 25.5 7.1 13.1 0.0 17.6 10.4 10.0 10.9 215.4 5.7 8.1 6.1 15.1 9.6 3.3 16.8 19.4 17.8 1.9 12.9 194.2 32.0 1.5 4.8 3.0 11.3 25.6 6.8 7.8 63.7 26.6 1.3 108.4 0.0 22.8 13.6 1.3 8.4 32.2 22.6 1.6 20.8 85.8 7.5 18.3 DCAF15 "C19orf72, MGC99481" ENSG00000132017 "DDB1 and CUL4 associated factor 15" Q66K64 19 13952492-13961449 "Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068351 Approved Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Mitochondria Vesicles "HPA068351: AB_2685977" "unprognostic (6.91e-2)" "unprognostic (6.55e-3)" "unprognostic (3.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.95e-1)" "unprognostic (1.89e-2)" "unprognostic (1.83e-3)" "unprognostic (9.72e-2)" "unprognostic (8.03e-2)" "unprognostic (1.21e-1)" "prognostic favorable (7.97e-4)" "unprognostic (1.98e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (7.97e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" 17.6 10.7 5.9 10.3 6.0 20.5 18.1 7.1 7.9 18.7 4.7 18.1 6.9 17.0 4.3 24.0 16.7 4.5 18.6 6.0 5.6 16.2 13.9 18.6 13.5 5.6 5.2 15.5 13.7 7.1 16.5 7.3 5.2 17.0 5.2 3.6 16.1 5.3 22.9 30.2 23.4 5.1 4.9 33.4 14.0 44.7 5.6 14.6 17.0 8.6 10.8 15.6 21.6 5.4 18.9 11.5 29.5 16.2 3.1 4.5 13.5 12.7 8.8 26.1 25.9 20.4 7.9 17.3 14.4 12.3 15.4 16.7 18.9 12.0 9.2 21.0 33.8 21.3 21.0 21.4 6.5 17.8 30.2 5.9 10.9 19.3 8.6 9.4 13.1 27.4 22.9 24.8 11.6 28.7 32.0 33.0 35.2 12.7 17.8 29.2 10.4 11.8 14.1 14.3 18.8 19.3 11.4 8.1 10.7 12.1 10.5 22.7 9.2 17.8 13.1 28.3 24.1 17.4 20.7 18.3 11.4 25.8 15.6 0.2 0.3 0.9 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.4 0.1 0.3 0.6 0.1 0.2 0.4 0.6 0.2 5.9 6.0 7.1 7.9 6.0 5.6 5.6 5.2 5.2 4.9 5.6 5.4 19.5 0.0 0.0 6.8 19.7 4.8 10.5 6.9 8.6 17.3 8.9 10.7 2.9 10.0 3.8 9.2 8.4 13.7 24.4 9.6 1.9 11.0 5.0 7.0 7.8 10.9 7.7 9.4 5.2 10.3 15.1 7.5 13.7 7.0 1.3 15.0 7.1 3.4 15.7 15.2 3.4 5.7 4.1 8.1 7.0 9.5 18.3 14.3 1.8 8.4 13.8 9.2 16.5 7.1 5.5 9.9 9.6 12.0 18.3 6.4 4.5 4.7 3.9 13.9 6.6 6.0 7.9 35.6 19.9 10.0 9.8 13.8 21.2 10.4 7.9 8.9 DCD "AIDD, DCD-1, DSEP, HCAP, PIF" ENSG00000161634 Dermcidin P81605 12 54644589-54648493 "Plasma proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 2476.8" "Cell type enriched" "Detected in some" 355 "Melanocytes: 8167.8" "Cancer enriched" "Detected in some" 9 "breast cancer: 91.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" HPA063967 Enhanced "Secreted in other tissues" NA NA 410000000 "Cluster 42: Non-specific - Transcription" "Cluster 61: Skin - Cornification" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA063967: AB_2685163" "unprognostic (3.55e-2)" "unprognostic (1.61e-1)" 100.2 0.4 3.5 0.3 3.3 1.1 354.3 3.4 5.4 0.3 3.8 0.7 0.2 0.7 0.9 0.5 0.2 0.8 1.3 3.5 3.3 0.2 0.9 0.6 0.2 3.3 3.6 0.4 1.0 0.0 0.5 0.1 3.5 0.4 0.2 0.5 0.5 0.1 14.0 2476.8 0.7 0.1 3.0 0.4 0.7 1.1 3.2 0.3 0.5 0.0 0.2 0.2 0.7 4.1 0.2 0.3 0.4 0.4 0.3 0.4 0.4 0.5 0.1 0.0 0.2 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.4 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.5 0.2 0.0 0.2 0.1 0.3 0.2 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 1.9 0.4 0.5 0.4 0.3 0.6 0.5 0.4 0.3 0.2 0.4 0.5 0.5 1.1 0.9 0.7 0.5 0.6 0.2 3.5 3.3 3.4 5.4 3.5 3.3 3.3 3.6 3.5 3.0 3.2 4.1 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.1 0.0 0.0 8167.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.4 0.2 0.0 23.0 0.0 1.0 0.0 0.0 0.0 DCDC2 "DCDC2A, DFNB66, KIAA1154, NPHP19, RU2" ENSG00000146038 "Doublecortin domain containing 2" Q9UHG0 6 24171755-24358059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Ciliopathy, Deafness, Disease variant, Nephronophthisis, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.1;kidney: 23.2;pancreas: 26.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 62.9;Collecting duct cells: 79.1;Distal tubular cells: 56.7;Ductal cells: 135.9;Endometrial ciliated cells: 160.3;Glandular and luminal cells: 102.4;Proximal tubular cells: 54.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 71.8;EFO-21: 48.3;Hep G2: 82.3;RPTEC TERT1: 254.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031582, HPA031583, HPA031584" Enhanced Supported "Microtubules,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Cytosol "Microtubules, Mitotic spindle, Centriolar satellite" "HPA031582: AB_10600901, HPA031583: AB_2673944, HPA031584: AB_2673945" "unprognostic (8.65e-2)" "unprognostic (2.07e-2)" "unprognostic (1.66e-1)" "unprognostic (6.70e-2)" "unprognostic (1.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.09e-1)" "unprognostic (2.67e-2)" "unprognostic (5.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.99e-2)" 0.0 1.3 0.8 0.0 1.2 0.1 4.4 0.3 0.8 1.6 15.1 0.7 0.6 4.4 5.3 0.0 7.6 3.9 0.0 0.8 1.0 23.2 2.2 3.4 0.0 2.2 2.7 0.2 26.2 8.2 1.2 0.6 1.7 1.2 0.6 1.4 0.4 2.3 0.3 0.1 0.1 0.1 2.0 0.1 1.8 3.7 1.1 0.1 8.2 0.2 0.0 0.4 0.0 1.6 0.0 8.8 0.5 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 71.8 0.2 0.0 48.3 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.2 0.0 0.0 82.3 0.0 0.0 0.0 0.0 0.0 9.7 0.0 1.4 0.0 0.2 0.1 0.0 0.3 10.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 254.5 0.3 5.2 0.5 0.0 1.3 0.0 0.2 12.3 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.2 0.3 0.8 0.8 1.0 2.2 2.7 1.7 2.0 1.1 1.6 0.2 19.2 14.4 3.9 1.4 0.1 0.6 0.3 0.0 0.0 20.3 11.7 0.3 62.9 6.1 79.1 0.0 0.4 0.0 1.2 56.7 135.9 40.1 160.3 5.3 0.4 3.6 0.0 11.3 8.4 0.0 1.3 3.6 102.4 0.0 4.1 0.0 1.0 0.5 0.0 8.3 2.9 0.0 0.0 0.0 14.6 0.3 1.0 0.0 1.0 2.0 2.3 0.0 1.0 0.5 27.9 4.1 0.4 0.0 1.3 0.0 54.3 37.1 0.1 0.0 0.0 2.4 32.3 2.6 0.0 0.1 0.1 1.1 5.6 2.7 0.9 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 107.4" "Cell type enriched" "Detected in some" 23 "Melanocytes: 3552.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 272 "SK-MEL-30: 257.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.4 0.4 0.6 0.0 1.0 0.1 3.0 0.4 0.7 0.2 0.2 0.3 0.0 0.3 0.9 0.0 0.9 0.1 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.6 0.6 0.4 0.4 0.0 1.6 0.0 0.5 0.3 0.0 0.9 1.5 0.3 0.4 107.4 0.1 0.1 0.6 0.1 0.1 0.6 0.6 0.5 0.2 0.1 0.0 0.2 0.3 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 257.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.7 0.6 0.6 0.6 0.6 0.5 0.6 0.6 0.5 0.0 0.0 0.0 23.5 0.0 152.3 0.1 0.0 0.0 1.0 0.3 0.5 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.5 0.1 1.2 0.0 0.0 16.1 0.2 0.0 1.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 25.5 23.8 0.9 0.0 3552.1 1.9 0.0 3.5 0.0 6.6 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 1.0 0.5 0.8 0.0 33.4 0.0 0.9 0.1 0.0 0.0 DCX "DBCN, DC, LISX, SCLH, XLIS" ENSG00000077279 Doublecortin O43602 X 111293779-111412429 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.7;endometrium 1: 1.4;retina: 2.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 39.1;Inhibitory neurons: 90.2;Oligodendrocyte precursor cells: 49.8;Rod photoreceptor cells: 21.8" "Cancer enriched" "Detected in some" 5 "glioma: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 52.5;SH-SY5Y: 22.1" "Region enriched" "Detected in many" 9 "olfactory bulb: 74.0" "Region enriched" "Detected in all" 4 "olfactory bulb: 68.6" HPA036121 Enhanced Supported Approved Cytosol NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA036121: AB_2674950" "unprognostic (1.36e-2)" "unprognostic (1.99e-1)" "unprognostic (7.36e-2)" "unprognostic (4.00e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.00e-2)" "unprognostic (7.18e-2)" "unprognostic (3.24e-2)" "unprognostic (2.33e-3)" "unprognostic (3.67e-1)" "unprognostic (4.90e-4)" "unprognostic (5.02e-3)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" 0.1 0.2 2.1 0.0 2.4 0.0 1.3 0.0 2.5 0.1 0.0 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.0 1.4 2.7 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.3 0.0 0.8 0.0 0.0 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 52.5 22.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 0.0 2.5 1.4 2.7 0.2 1.3 0.8 0.0 2.4 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.5 1.6 2.2 0.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 39.1 0.0 0.2 6.8 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 90.2 0.2 0.0 0.0 0.4 0.5 0.0 0.0 1.8 1.9 0.0 1.6 0.0 49.8 2.3 0.1 0.0 1.5 0.0 0.0 0.0 0.1 0.0 21.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.2 0.0 0.0 DDA1 "C19orf58, MGC2594, PCIA1" ENSG00000130311 "DET1 and DDB1 associated 1" Q9BW61 19 17309518-17323298 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 416.9;Syncytiotrophoblasts: 253.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042134, HPA055272" Approved Approved Nucleoplasm,Nucleoli No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA042134: AB_10794169, HPA055272: AB_2682767" "unprognostic (1.30e-1)" "unprognostic (6.35e-3)" "unprognostic (3.13e-2)" "unprognostic (1.49e-3)" "unprognostic (5.38e-2)" "unprognostic (1.26e-2)" "unprognostic (3.41e-2)" "unprognostic (4.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.55e-2)" "unprognostic (1.47e-1)" "unprognostic (8.55e-2)" "unprognostic (1.48e-1)" "unprognostic (4.38e-2)" "unprognostic (6.33e-2)" "unprognostic (1.45e-1)" "unprognostic (3.15e-3)" 7.9 11.5 15.8 5.1 14.4 7.1 7.8 12.2 19.9 7.8 10.4 11.5 5.7 8.6 3.4 10.9 8.4 4.0 12.0 14.7 15.3 9.8 10.9 9.6 6.2 14.0 15.0 7.3 6.8 6.1 8.0 8.0 14.4 10.0 4.8 3.8 8.7 5.4 9.5 13.0 11.2 4.2 13.1 9.9 10.1 10.1 15.2 7.3 7.9 5.0 4.7 9.3 8.0 13.2 15.6 13.5 10.1 8.2 10.5 7.5 15.6 10.1 13.0 15.4 14.1 12.0 13.8 6.0 13.7 10.6 7.3 13.2 7.5 15.0 7.8 9.9 19.4 7.2 11.1 11.5 12.5 8.3 14.2 11.5 17.5 9.3 8.7 9.5 9.1 13.9 8.9 10.7 8.4 7.8 17.5 12.7 11.7 16.0 22.3 11.0 7.8 10.3 12.6 11.5 10.4 15.2 7.3 17.8 9.5 6.1 9.0 11.6 13.7 10.6 8.7 26.9 14.6 12.8 18.2 8.6 23.3 14.4 10.6 3.0 3.8 6.4 4.2 4.3 3.6 3.7 3.5 4.2 3.2 3.2 3.9 3.9 4.0 3.4 3.8 6.8 4.8 3.4 15.8 14.4 12.2 19.9 14.7 15.3 14.0 15.0 14.4 13.1 15.2 13.2 24.4 28.9 14.1 13.4 26.3 54.6 38.6 84.0 30.1 18.4 41.8 30.5 17.1 11.5 54.2 27.6 12.5 140.5 38.5 70.4 39.2 77.2 416.9 48.6 32.8 26.4 20.3 29.9 10.4 46.4 152.8 26.8 34.7 53.7 38.7 25.2 20.3 26.3 65.0 13.5 9.8 43.4 54.9 22.4 36.8 130.3 22.4 34.2 30.2 7.5 57.2 34.1 58.7 4.5 10.8 139.6 79.9 27.1 31.8 41.4 47.4 55.1 43.7 19.0 19.7 19.5 36.0 107.7 40.0 36.8 61.8 253.5 34.2 31.5 28.6 89.5 DDB2 "DDBB, FLJ34321, UV-DDB2, XPE" ENSG00000134574 "Damage specific DNA binding protein 2" Q92466 11 47214465-47239217 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;monocytes: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025912, HPA058406" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cell Junctions" "CAB025912: , HPA058406: AB_2683708" "prognostic favorable (7.29e-4)" "prognostic favorable (1.58e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.20e-4)" "unprognostic (4.29e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-2)" "unprognostic (6.18e-2)" "unprognostic (2.25e-1)" "unprognostic (3.58e-3)" "unprognostic (3.53e-1)" "unprognostic (1.94e-1)" "unprognostic (4.57e-3)" "unprognostic (1.21e-2)" "unprognostic (4.25e-2)" "unprognostic (9.82e-3)" "unprognostic (1.07e-1)" 13.2 22.5 2.6 8.2 3.2 11.6 13.5 3.4 3.6 12.5 3.4 12.8 7.6 12.7 11.7 24.8 17.6 12.5 6.8 2.5 2.4 4.4 27.0 12.2 14.7 3.4 2.7 11.6 14.4 4.8 4.7 6.8 3.5 9.7 14.9 2.3 14.4 11.7 6.2 46.7 10.2 13.9 2.7 11.3 9.5 4.5 3.2 23.5 5.5 6.9 17.0 11.2 14.1 3.6 23.7 62.3 25.9 19.3 16.6 32.7 29.9 26.0 58.8 32.0 37.1 10.1 14.1 56.6 5.3 23.2 23.6 40.8 14.6 51.8 15.7 14.5 27.5 13.3 55.7 46.7 15.8 15.9 34.4 43.4 58.0 15.9 35.2 10.2 94.2 14.7 3.5 27.0 52.7 44.4 60.4 7.7 8.4 31.1 22.3 30.3 5.6 30.6 13.5 22.7 13.2 16.7 31.2 8.7 8.1 30.8 56.1 5.5 41.2 96.8 44.1 21.3 12.6 27.6 22.4 12.5 37.0 20.2 35.9 9.8 12.8 20.2 19.3 18.4 18.8 18.3 20.1 18.8 10.4 14.5 14.8 15.7 3.7 14.1 15.8 0.3 47.7 15.9 2.6 3.2 3.4 3.6 2.5 2.4 3.4 2.7 3.5 2.7 3.2 3.6 13.8 16.0 22.2 7.8 25.1 38.9 39.7 28.1 75.1 5.0 18.0 25.8 7.8 11.5 16.3 5.5 10.4 3.6 21.3 11.1 9.8 12.5 1.5 5.2 8.1 19.5 7.7 19.1 6.6 13.8 9.0 16.0 18.3 9.5 22.8 31.2 15.0 16.6 17.5 1.7 1.4 12.6 16.2 17.5 12.8 2.1 19.0 16.8 19.6 24.4 135.5 9.6 35.0 1.0 10.6 19.9 9.8 10.5 34.1 8.9 15.7 7.7 13.9 12.8 0.0 12.1 14.0 3.1 8.6 34.5 30.3 1.5 34.3 25.4 16.5 26.5 DDC AADC ENSG00000132437 "Dopa decarboxylase" P20711 7 50458436-50565405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 165.8;kidney: 314.9;retina: 175.6" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 410.3;Proximal enterocytes: 391.5;Proximal tubular cells: 429.5;Rod photoreceptor cells: 498.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.5;liver cancer: 13.4;pancreatic cancer: 6.4;renal cancer: 18.7;stomach cancer: 9.9" "Group enriched" "Detected in many" 9 "midbrain: 86.3;pons: 29.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "CACO-2: 54.5;Hep G2: 49.3;OE19: 83.6;SCLC-21H: 130.9;SH-SY5Y: 135.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "midbrain: 74.5;pons: 29.4" HPA017742 Enhanced Approved "Actin filaments" NA NA 120000 "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Actin filaments" "HPA017742: AB_1847832" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (2.57e-2)" "unprognostic (3.49e-5)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.15e-2)" "unprognostic (4.69e-2)" "unprognostic (5.44e-2)" "unprognostic (9.36e-3)" "unprognostic (5.24e-2)" "unprognostic (1.76e-3)" "unprognostic (1.60e-1)" "unprognostic (3.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.16e-1)" 0.5 48.9 0.1 2.3 0.7 0.0 1.0 0.0 0.6 0.0 0.2 36.5 154.8 0.0 9.1 0.1 0.0 0.1 0.0 0.2 2.2 314.9 54.6 2.0 0.1 6.1 86.3 0.8 15.8 0.0 0.0 0.0 29.4 0.6 37.5 175.6 0.0 0.0 0.0 0.1 165.8 1.7 0.0 0.1 18.1 1.5 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.3 0.0 0.0 11.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 83.6 0.0 0.0 0.0 0.7 1.3 0.0 130.9 135.9 0.0 4.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.6 0.2 2.2 6.1 86.3 29.4 0.0 1.9 0.2 0.0 0.0 12.2 0.0 2.5 0.0 0.0 0.0 0.0 89.3 0.1 0.1 0.4 2.8 0.6 3.7 41.7 0.0 0.0 34.4 25.4 0.1 6.6 0.1 0.0 1.8 410.3 0.0 0.3 0.9 0.1 0.1 0.0 0.4 0.0 0.0 1.1 67.2 0.1 3.3 0.4 67.8 0.0 1.3 0.0 5.4 0.0 2.5 0.0 0.0 0.0 45.1 0.0 0.0 0.1 0.2 31.8 0.0 0.0 0.3 391.5 429.5 0.0 498.9 0.0 0.0 0.0 4.0 0.4 0.0 0.0 0.1 1.3 0.1 88.7 0.2 DDO ENSG00000203797 "D-aspartate oxidase" Q99489 6 110391771-110415575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.4;Muller glia cells: 8.2;Oligodendrocytes: 13.3;Paneth cells: 8.5;Proximal enterocytes: 8.5;Proximal tubular cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.3;myeloid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 11.5;RPMI-8226: 15.9;U-937: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037525, HPA037526" Enhanced Enhanced Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA037525: AB_2675523, HPA037526: AB_10672352" "unprognostic (1.37e-1)" "unprognostic (1.54e-1)" "unprognostic (6.51e-2)" "unprognostic (1.30e-2)" "unprognostic (2.00e-1)" "unprognostic (3.28e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.91e-1)" "unprognostic (6.97e-2)" "unprognostic (1.43e-1)" "prognostic favorable (8.69e-5)" "unprognostic (3.51e-4)" "unprognostic (3.36e-3)" "unprognostic (1.27e-3)" "unprognostic (9.06e-2)" 1.9 8.2 4.5 0.8 7.0 1.4 2.5 5.0 4.8 1.9 4.3 2.3 7.4 2.1 2.7 0.8 4.9 2.9 18.4 4.4 4.5 10.6 11.1 3.2 1.0 5.4 4.9 0.3 2.6 5.3 1.2 1.6 5.3 2.0 3.2 2.4 4.2 2.3 10.9 0.4 7.0 2.2 4.8 2.1 1.1 0.1 4.7 0.4 1.3 7.4 0.2 1.6 0.9 5.9 0.2 0.0 0.0 0.1 0.0 0.2 1.1 0.1 5.4 1.3 0.9 0.0 0.1 0.0 0.7 0.7 11.5 0.0 0.0 0.0 2.3 5.0 0.0 5.1 0.1 4.3 1.6 0.0 0.0 0.1 0.0 2.7 0.1 2.3 0.0 0.0 0.0 1.9 4.5 0.0 0.0 0.2 0.0 0.0 0.1 0.1 3.0 15.9 0.0 4.9 0.1 0.2 0.0 0.5 0.6 0.0 0.7 1.1 0.9 1.0 0.1 0.0 2.6 0.1 0.4 0.0 2.0 17.4 0.0 0.0 2.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 1.1 1.0 0.0 0.0 1.1 4.5 7.0 5.0 4.8 4.4 4.5 5.4 4.9 5.3 4.8 4.7 5.9 1.1 0.0 0.0 4.9 0.0 0.0 0.7 0.7 0.6 0.0 1.4 1.1 17.4 0.0 0.4 0.0 2.1 0.2 0.1 1.8 3.9 4.5 0.3 3.6 0.5 0.7 4.2 0.0 0.0 2.2 0.2 0.6 0.0 0.9 0.0 0.1 2.5 4.9 1.7 0.0 0.1 6.0 0.0 3.1 0.4 0.0 0.3 1.6 0.0 0.0 2.0 8.2 0.0 3.5 13.3 0.8 8.5 0.0 0.0 0.4 8.5 12.9 2.2 0.2 0.0 2.1 1.2 0.0 0.0 0.2 0.0 0.0 0.2 0.3 5.0 0.5 DDX31 "FLJ13633, FLJ14578, FLJ23349, PPP1R25" ENSG00000125485 "DEAD-box helicase 31" Q9H8H2 9 132592997-132670401 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020891 Supported "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoli "Golgi apparatus, Vesicles" "HPA020891: " "unprognostic (5.71e-2)" "unprognostic (1.76e-2)" "unprognostic (2.56e-1)" "unprognostic (7.91e-2)" "unprognostic (5.79e-2)" "unprognostic (9.94e-2)" "prognostic unfavorable (1.68e-7)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.66e-1)" "unprognostic (3.90e-2)" "unprognostic (9.57e-3)" "unprognostic (4.57e-3)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" 3.9 3.8 3.3 5.3 3.9 4.2 6.3 8.8 3.2 4.8 4.0 3.9 3.1 4.5 5.0 5.7 5.2 3.6 3.3 2.8 3.7 6.0 5.5 4.5 6.6 5.1 3.8 9.9 5.8 5.4 4.2 3.5 5.7 5.4 4.7 3.2 8.2 4.3 6.1 8.4 4.2 4.2 2.9 4.8 4.0 6.0 3.6 5.5 13.8 4.2 7.2 5.2 4.9 4.7 12.4 22.2 10.8 14.4 12.4 11.1 20.4 12.9 12.2 19.2 14.5 24.9 24.1 29.9 11.2 11.7 20.8 33.5 32.8 14.6 15.4 18.4 12.3 16.4 19.5 13.1 14.9 29.7 12.8 9.9 19.5 19.7 27.5 7.5 12.7 22.1 30.6 11.4 16.1 26.3 20.6 15.9 26.2 35.4 22.2 21.4 19.3 34.6 17.5 11.4 18.8 13.5 23.4 20.2 18.0 12.2 42.8 8.4 11.1 32.5 15.0 18.7 19.8 5.5 18.8 23.5 12.0 18.2 25.2 0.0 1.1 1.2 3.1 1.6 2.4 2.1 2.9 2.4 2.5 2.7 3.6 2.7 0.2 2.0 1.1 1.6 2.0 1.7 3.3 3.9 8.8 3.2 2.8 3.7 5.1 3.8 5.7 2.9 3.6 4.7 3.3 6.4 6.0 16.6 7.2 5.6 4.5 3.0 9.1 4.3 5.9 8.1 4.4 0.0 10.2 7.3 4.2 5.7 4.7 3.6 1.9 6.2 4.1 3.9 6.6 3.6 24.6 1.7 9.7 5.4 6.8 4.4 4.1 4.6 1.3 6.1 2.9 4.1 5.2 1.7 13.9 5.8 6.1 2.9 1.8 3.0 18.0 2.9 1.8 5.6 4.5 1.7 8.2 26.7 17.1 5.9 1.2 13.2 5.7 5.8 0.7 7.1 5.7 3.7 0.0 4.1 3.4 14.0 13.7 8.8 6.3 3.0 5.0 5.7 6.1 3.5 DDX49 "Dbp8, FLJ10432" ENSG00000105671 "DEAD-box helicase 49" Q9Y6V7 19 18919705-18929189 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041870, HPA048093" Enhanced Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA041870: AB_2677717, HPA048093: AB_2680262" "unprognostic (3.51e-1)" "prognostic favorable (2.01e-6)" "unprognostic (2.28e-2)" "unprognostic (1.28e-1)" "unprognostic (8.56e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (4.12e-2)" "unprognostic (2.41e-3)" "unprognostic (8.67e-2)" "unprognostic (6.46e-3)" "unprognostic (5.13e-2)" "prognostic unfavorable (7.44e-5)" "unprognostic (3.93e-2)" "unprognostic (2.99e-2)" "unprognostic (4.97e-2)" "unprognostic (3.24e-1)" 16.5 17.7 17.1 13.9 17.3 23.3 15.5 17.9 22.1 16.0 14.0 17.4 15.7 15.9 5.9 25.9 13.9 7.9 18.2 18.2 16.5 15.6 24.9 13.7 16.1 17.1 16.0 14.6 20.1 12.6 11.3 13.4 16.7 16.4 7.4 4.8 18.0 10.8 33.6 27.1 14.8 9.9 17.7 16.1 15.7 19.2 17.3 14.1 13.6 13.6 10.3 17.5 17.5 19.3 46.5 47.4 19.0 61.3 28.1 21.1 71.0 29.2 19.8 50.9 40.1 54.6 45.8 60.6 86.7 29.1 16.1 39.4 42.9 39.8 14.8 18.9 110.5 29.9 49.9 48.6 63.5 77.5 40.1 44.4 35.9 40.7 41.9 14.4 23.3 46.9 58.2 43.1 18.2 104.4 56.6 37.9 62.7 50.3 112.8 62.8 31.5 65.9 27.4 28.2 67.2 69.7 38.2 36.6 48.2 9.8 39.2 37.6 29.5 24.3 27.9 92.0 48.7 55.5 73.0 57.1 31.1 88.8 39.3 17.1 21.9 16.7 14.8 26.2 12.0 9.1 11.0 11.1 31.1 9.8 10.9 12.1 8.6 19.5 18.1 13.7 18.0 12.7 17.1 17.3 17.9 22.1 18.2 16.5 17.1 16.0 16.7 17.7 17.3 19.3 15.6 3.2 10.0 4.9 20.5 22.6 18.7 28.0 14.8 19.5 25.2 29.1 13.8 27.1 20.5 18.4 4.2 46.5 27.0 48.0 37.2 35.0 37.2 18.8 26.5 15.3 25.8 18.3 7.4 52.2 50.3 19.0 19.4 24.7 18.4 25.1 7.5 14.8 33.5 10.1 7.6 31.5 30.5 21.0 22.0 103.0 21.5 18.8 26.6 4.7 28.5 18.3 29.9 6.0 8.2 29.8 30.7 19.9 29.5 21.5 48.0 25.0 12.5 24.1 19.7 21.1 26.9 33.4 31.8 29.5 28.3 42.1 20.8 38.1 39.4 21.5 DEF6 "IBP, SLAT, SWAP70L" ENSG00000023892 "DEF6 guanine nucleotide exchange factor" Q9H4E7 6 35297818-35321771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2;lymphoid tissue: 62.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 94.0;Late spermatids: 151.4;NK-cells: 88.6;T-cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 83.3;MOLT-4: 75.5;NB-4: 99.3;REH: 68.8;THP-1: 78.9;U-937: 117.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA038975, HPA038976" Enhanced Enhanced Nucleoplasm Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA038975: AB_10697544, HPA038976: AB_10673409" "prognostic favorable (3.02e-6)" "prognostic favorable (1.08e-4)" "prognostic unfavorable (1.71e-4)" "prognostic favorable (2.37e-4)" "unprognostic (1.93e-1)" "unprognostic (3.63e-3)" "unprognostic (2.24e-1)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "unprognostic (6.21e-3)" "prognostic unfavorable (1.02e-8)" "unprognostic (1.78e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (1.45e-3)" 5.8 3.6 5.9 33.5 5.9 63.2 6.0 6.3 7.2 8.0 7.3 9.8 10.2 2.8 8.5 28.2 4.4 7.2 2.6 5.9 6.6 4.7 5.2 14.7 48.6 8.7 7.0 3.1 21.6 1.3 8.3 7.7 8.0 21.0 7.4 2.2 15.8 4.8 1.7 28.5 30.7 3.5 7.7 62.9 16.3 26.7 8.1 50.2 8.3 1.1 38.1 10.2 16.5 8.8 24.0 0.0 0.8 0.6 0.1 0.3 29.0 2.6 3.6 0.6 0.7 1.5 10.0 28.1 8.3 1.3 0.1 15.5 0.0 19.6 0.4 1.0 1.1 31.7 0.4 12.6 0.7 57.5 40.0 4.5 24.6 0.3 22.0 0.1 0.0 83.3 14.3 65.7 0.1 12.3 75.5 99.3 1.3 3.0 2.8 68.8 0.6 38.4 2.5 17.8 0.4 0.2 2.1 5.8 5.5 1.1 15.9 78.9 3.8 0.3 0.6 0.1 0.3 37.2 37.1 23.3 0.0 117.7 0.2 49.2 39.5 119.7 78.6 29.7 62.4 34.2 63.3 76.8 55.2 31.3 65.1 65.2 69.3 72.9 27.8 36.6 73.1 64.3 5.9 5.9 6.3 7.2 5.9 6.6 8.7 7.0 8.0 7.7 8.1 8.8 1.7 6.4 8.0 1.3 49.2 11.9 16.9 15.0 20.5 2.5 5.4 7.2 0.8 2.8 8.2 5.5 0.0 25.0 52.3 4.2 0.0 0.9 56.3 2.2 0.8 3.1 4.2 6.7 2.0 10.0 17.2 2.2 26.0 3.0 17.7 1.5 2.9 0.9 94.0 3.3 1.0 9.9 2.0 28.0 26.4 151.4 2.8 31.7 7.2 17.8 30.0 0.8 88.6 0.5 0.5 8.0 8.9 1.9 57.9 6.0 3.1 0.3 5.8 1.7 0.0 0.6 1.2 40.0 0.9 20.0 11.8 12.6 78.3 1.0 9.1 13.0 DEGS1 "DEGS-1, Des-1, DES1, FADS7, MLD" ENSG00000143753 "Delta 4-desaturase, sphingolipid 1" O15121 1 224175756-224193441 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skin 1: 535.6" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 246.0;Cytotrophoblasts: 281.8;Suprabasal keratinocytes: 320.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076422 Supported Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA076422: AB_2686799" "unprognostic (2.34e-2)" "unprognostic (6.91e-2)" "unprognostic (2.48e-2)" "prognostic unfavorable (7.74e-5)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.29e-5)" "unprognostic (7.70e-2)" "unprognostic (2.31e-1)" "unprognostic (3.20e-1)" "unprognostic (3.63e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (2.87e-1)" "unprognostic (1.61e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (2.53e-4)" 60.3 31.0 30.3 44.9 33.1 69.5 61.9 35.0 36.2 53.4 42.5 50.8 47.0 44.5 29.5 48.6 34.4 40.5 43.8 31.3 35.6 38.1 35.7 49.1 48.0 36.6 35.2 27.1 22.5 31.5 34.8 128.7 35.9 83.2 27.2 20.8 38.7 58.6 20.9 535.6 33.4 70.9 37.9 38.7 38.6 22.7 34.0 34.2 52.3 23.3 50.9 48.4 72.7 44.5 72.8 50.7 65.2 49.5 275.7 181.1 51.2 201.1 223.8 137.5 164.2 47.1 55.2 58.0 252.4 181.0 82.4 76.3 76.5 67.9 153.0 84.2 141.5 41.7 51.1 29.2 167.9 84.2 86.1 177.4 153.6 125.5 69.9 143.0 140.4 31.4 62.8 61.8 181.2 27.5 43.2 46.9 83.3 40.0 76.1 38.8 92.4 37.5 181.1 19.8 42.3 69.8 106.6 169.4 110.4 118.8 57.1 123.4 125.7 133.4 41.4 153.1 197.5 44.5 55.3 52.8 141.9 41.7 154.2 104.6 61.4 120.3 30.9 67.8 59.8 58.2 52.7 43.3 104.4 74.3 40.7 37.0 67.7 43.9 48.7 34.9 59.0 52.8 30.3 33.1 35.0 36.2 31.3 35.6 36.6 35.2 35.9 37.9 34.0 44.5 71.7 83.3 29.3 13.4 69.9 246.0 44.0 33.6 89.4 31.2 40.7 38.4 20.8 10.0 19.8 11.0 14.6 281.8 40.5 4.0 13.7 34.9 27.9 54.0 90.2 66.7 14.9 18.7 17.4 43.3 48.3 77.7 21.4 146.1 106.5 21.3 55.6 20.8 93.0 18.5 20.4 6.2 34.6 57.8 90.5 13.6 63.0 72.8 69.4 20.6 57.1 26.0 10.3 25.6 32.1 29.5 5.9 79.4 50.1 44.2 20.1 29.7 20.1 18.4 105.2 42.7 89.1 84.3 44.0 50.4 320.4 198.9 58.9 43.7 6.6 13.7 DEPDC1 "DEP.8, DEPDC1A, FLJ20354, SDP35" ENSG00000024526 "DEP domain containing 1" Q5TB30 1 68474152-68497221 "Predicted intracellular proteins" "Transcription, Transcription regulation" "GTPase activation, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.1;testis: 8.1" "Cell type enhanced" "Detected in many" "Early spermatids: 44.9;Erythroid cells: 31.8;Extravillous trophoblasts: 35.2;Late spermatids: 73.0;Spermatocytes: 86.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017845 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB017845: " "unprognostic (2.73e-1)" "unprognostic (7.40e-2)" "prognostic favorable (8.70e-5)" "unprognostic (1.23e-3)" "unprognostic (3.06e-1)" "unprognostic (7.73e-3)" "unprognostic (4.37e-6)" "unprognostic (3.39e-3)" "unprognostic (1.57e-3)" "unprognostic (8.59e-2)" "unprognostic (9.04e-6)" "unprognostic (2.18e-1)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (2.27e-1)" "unprognostic (2.83e-2)" "unprognostic (1.11e-1)" 0.3 0.1 0.0 2.6 0.0 5.0 0.6 0.0 0.1 0.4 0.0 2.9 2.5 0.5 0.1 2.4 0.1 0.5 0.1 0.1 0.0 0.0 0.4 0.2 4.8 0.0 0.1 0.0 0.0 0.2 0.0 3.2 0.1 2.1 3.5 0.0 0.3 0.1 0.0 1.6 2.4 1.5 0.0 0.6 1.2 8.1 0.2 8.1 0.3 0.2 4.8 0.9 0.7 0.2 47.2 21.5 40.0 18.5 2.5 5.6 31.3 58.9 26.9 49.1 42.1 17.9 19.3 0.0 42.8 24.4 78.6 30.8 58.6 30.7 82.4 41.2 38.2 38.3 35.9 10.5 0.6 33.4 0.0 2.1 1.6 56.3 31.2 10.0 36.0 16.5 26.6 36.1 88.3 10.7 0.1 12.5 34.6 19.5 28.9 0.0 118.7 15.3 19.8 12.7 44.8 20.7 59.0 24.9 30.3 25.6 22.5 16.6 21.3 31.5 35.5 56.0 69.2 22.5 52.2 0.5 29.7 11.4 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.4 0.0 0.0 0.3 2.0 3.3 0.8 3.3 1.2 0.4 1.3 1.8 0.8 0.0 0.5 1.8 0.0 20.6 0.4 2.1 0.0 0.2 44.9 4.0 1.6 1.6 0.0 31.8 0.5 0.0 35.2 4.4 8.2 2.0 0.0 17.5 2.2 1.2 8.6 0.0 2.2 5.3 4.1 3.5 1.0 73.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 6.9 2.2 0.5 0.1 0.9 0.2 0.0 0.6 4.0 86.8 19.6 12.2 1.3 2.9 1.6 0.5 8.8 1.7 DEPDC1B "BRCC3, XTP1" ENSG00000035499 "DEP domain containing 1B" Q8WUY9 5 60596912-60700190 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.1;gallbladder: 21.0;lymphoid tissue: 20.7;testis: 12.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 18.6;Erythroid cells: 23.8;Extravillous trophoblasts: 21.6;Spermatocytes: 37.2;Syncytiotrophoblasts: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038255, HPA072558" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA038255: AB_10669521, HPA072558: AB_2686534" "unprognostic (1.38e-1)" "unprognostic (1.99e-2)" "prognostic favorable (2.42e-4)" "prognostic unfavorable (8.55e-4)" "unprognostic (2.23e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (3.08e-4)" "prognostic unfavorable (6.93e-5)" "unprognostic (2.13e-2)" "unprognostic (8.14e-2)" "unprognostic (1.47e-3)" "unprognostic (2.44e-2)" "unprognostic (1.11e-16)" "unprognostic (1.00e-1)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (8.62e-2)" 0.3 0.2 0.4 3.9 0.7 11.1 0.9 0.5 0.5 0.6 0.1 4.1 6.0 0.6 0.0 2.5 0.2 21.0 0.1 0.3 0.6 2.9 0.4 0.4 9.1 1.2 0.5 0.2 0.1 0.0 0.0 7.5 1.4 0.2 5.5 0.1 0.5 0.1 0.0 2.1 6.4 0.9 0.6 1.6 1.4 12.6 0.6 20.7 1.2 0.0 9.7 1.0 1.1 1.5 61.0 20.3 60.5 37.2 1.3 1.9 66.2 16.1 10.9 27.7 35.8 34.0 37.5 34.6 38.5 5.0 36.0 19.8 49.2 36.1 36.9 49.5 35.5 43.3 22.7 42.6 1.0 36.7 40.3 1.2 3.7 9.0 12.9 5.4 26.1 36.3 31.4 45.8 24.7 38.0 59.8 31.9 44.7 13.0 32.6 65.4 49.2 29.4 22.8 29.9 33.6 15.4 37.7 13.4 17.7 27.0 24.9 28.8 12.1 11.7 34.2 9.5 41.6 23.0 43.3 68.0 14.7 53.2 33.3 1.5 0.1 0.9 0.2 0.0 0.2 0.4 1.0 0.7 0.3 0.0 0.1 0.1 0.0 0.6 0.0 0.0 3.2 0.4 0.4 0.7 0.5 0.5 0.3 0.6 1.2 0.5 1.4 0.6 0.6 1.5 0.2 0.0 1.8 0.0 1.9 4.7 1.0 1.5 0.0 0.1 0.5 0.8 0.1 18.6 0.3 0.0 0.0 7.4 1.1 3.1 0.0 0.3 1.9 3.3 1.4 0.9 0.0 23.8 5.5 0.2 21.6 1.1 2.6 11.7 3.8 5.2 0.0 0.3 6.4 0.0 1.7 2.3 0.0 1.6 2.9 2.4 0.3 1.9 0.0 4.7 0.1 0.2 0.0 2.0 7.0 0.9 5.8 0.0 15.9 0.7 3.7 1.0 0.1 0.1 6.6 0.3 1.4 37.2 12.7 5.8 2.0 46.9 4.5 0.6 7.9 0.9 DES "CMD1I, CSM1, CSM2" ENSG00000175084 Desmin P17661 2 219418377-219426734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cancer-related genes, Cardiomyopathy, Desmin-related myopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13020.7;intestine: 8627.2;skeletal muscle: 16532.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2531.9" "Cancer enhanced" "Detected in all" "prostate cancer: 562.1;stomach cancer: 400.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 70.2;LHCN-M2: 145.3;NB-4: 39.5;RH-30: 333.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "midbrain: 29.5" "CAB000034, HPA018803" Enhanced Supported "Intermediate filaments" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB000034: , HPA018803: AB_1847616" "unprognostic (1.75e-1)" "unprognostic (1.95e-3)" "unprognostic (3.43e-2)" "unprognostic (8.76e-2)" "unprognostic (7.75e-3)" "unprognostic (6.61e-3)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (4.67e-1)" "unprognostic (3.84e-2)" "unprognostic (2.57e-1)" "unprognostic (7.43e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (3.49e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (9.25e-3)" 235.3 57.1 2.1 436.2 4.9 1.1 51.2 2.1 9.6 504.3 5.0 8627.2 291.3 3015.2 86.0 1481.2 1085.0 452.1 13020.7 2.4 2.5 37.6 15.5 173.9 7.2 3.4 2.5 171.8 14.6 0.5 8.4 52.7 2.4 2218.8 245.6 0.0 255.3 2253.1 16532.0 152.4 1343.5 2557.5 2.1 25.2 1965.6 16.1 2.6 3.2 66.2 5753.8 1.2 4761.8 669.4 2.4 0.0 0.0 0.1 0.0 0.0 2.2 5.3 0.2 0.0 0.1 0.1 0.5 0.0 0.0 9.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 17.0 0.1 1.3 70.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 145.3 0.0 0.0 39.5 0.5 0.0 0.0 0.0 333.1 2.1 0.0 0.0 0.2 1.2 0.0 0.0 0.0 9.2 0.0 5.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.1 4.9 2.1 9.6 2.4 2.5 3.4 2.5 2.4 2.1 2.6 2.4 0.4 0.0 0.0 0.0 0.0 4.1 2.7 0.0 0.0 0.0 0.1 0.0 2531.9 1.5 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 90.6 0.5 6.7 22.7 0.0 0.0 0.1 0.0 5.2 104.6 0.0 0.1 0.0 0.0 1.8 0.0 5.6 0.0 0.0 0.9 0.0 0.0 10.7 71.6 28.9 2.8 12.4 0.0 0.6 0.0 0.0 0.5 0.0 0.5 0.0 50.4 0.0 8.7 0.0 0.1 0.0 0.0 46.0 497.8 210.5 5.0 5.1 0.1 9.8 8.5 2.4 0.0 0.2 2.9 DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 476.0;breast: 133.6;liver: 331.8;skin 1: 151.5" "Cell type enhanced" "Detected in many" "Early spermatids: 259.3;Hepatocytes: 116.4;Late spermatids: 64.1;Spermatocytes: 53.9;Spermatogonia: 53.5" "Cancer enhanced" "Detected in many" "liver cancer: 19.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 137.7;neutrophil: 348.6" "Lineage enriched" "Detected in many" 16 "granulocytes: 348.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.4;HDLM-2: 62.5;Hep G2: 64.9;OE19: 124.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 22.0" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA013351: AB_1847630" "unprognostic (2.28e-1)" "unprognostic (3.69e-1)" "unprognostic (9.38e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.63e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "unprognostic (7.59e-2)" "unprognostic (4.46e-1)" "unprognostic (4.12e-3)" "unprognostic (2.87e-1)" "unprognostic (2.99e-1)" "unprognostic (1.49e-7)" "unprognostic (2.03e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (5.60e-2)" 476.0 5.1 5.8 19.4 11.7 7.2 133.6 2.9 6.1 2.6 5.3 9.0 14.5 1.2 1.8 24.1 2.1 5.8 11.7 5.7 6.4 3.4 331.8 5.6 4.0 3.7 3.9 1.8 4.6 2.1 1.6 1.5 5.5 2.2 4.9 0.6 10.5 1.6 4.1 151.5 16.5 2.8 3.4 15.0 12.8 38.1 6.9 4.3 8.8 5.6 18.2 21.3 12.6 5.1 13.3 6.4 0.4 11.2 80.4 6.4 1.0 1.3 1.7 1.6 1.0 46.6 13.5 21.1 16.8 0.3 11.9 0.5 1.8 6.5 4.4 62.5 1.2 1.5 4.0 64.9 0.9 7.4 7.2 26.8 33.6 7.3 10.6 4.4 1.2 20.9 1.2 27.6 0.7 8.5 5.1 16.7 3.6 124.0 31.5 0.0 0.1 24.8 1.2 35.8 22.6 1.4 12.3 1.9 2.9 2.7 4.4 26.6 1.6 14.1 7.0 0.3 9.1 16.3 40.0 28.8 10.2 23.7 25.3 19.4 22.1 137.7 0.0 4.4 0.4 7.4 0.4 0.0 6.1 7.6 0.1 0.2 348.6 0.0 5.0 1.8 0.0 5.7 5.8 11.7 2.9 6.1 5.7 6.4 3.7 3.9 5.5 3.4 6.9 5.1 3.2 6.4 5.4 0.3 5.0 1.1 0.9 3.0 0.6 0.9 5.2 7.0 3.5 0.0 2.7 0.0 2.1 0.5 0.3 0.6 0.0 1.7 259.3 3.3 0.2 0.5 1.2 2.7 2.9 0.5 0.1 0.7 10.7 0.2 0.0 2.1 2.9 116.4 2.2 1.7 1.3 4.8 0.0 4.1 13.1 64.1 2.1 4.2 1.8 0.0 4.0 0.4 0.0 0.0 1.0 3.7 2.2 0.7 0.9 2.8 1.2 2.2 3.4 0.0 6.6 0.6 1.0 53.9 53.5 0.3 8.0 0.8 0.5 0.2 3.0 15.7 DGAT2L6 "DC3, FLJ25989" ENSG00000184210 "Diacylglycerol O-acyltransferase 2 like 6" Q6ZPD8 X 70177483-70205704 "Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "breast: 2.1;skin 1: 5.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "unprognostic (1.90e-2)" "unprognostic (3.08e-1)" "unprognostic (1.43e-3)" "unprognostic (3.47e-3)" "unprognostic (8.60e-2)" "unprognostic (5.82e-2)" "unprognostic (1.63e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DGKA "DAGK, DAGK1, DGK-alpha" ENSG00000065357 "Diacylglycerol kinase alpha" P23743 12 55927319-55954027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 101.5;lymphoid tissue: 198.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 49.0;Squamous epithelial cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "T-cells: 86.9" "Cell line enhanced" "Detected in many" "HBEC3-KT: 130.4;hTERT-HME1: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041645, HPA045462" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 58: T-cells - T-cell receptor" Vesicles "Nucleoplasm, Mitochondria" "HPA041645: AB_2677595, HPA045462: AB_2679335" "unprognostic (1.12e-3)" "unprognostic (1.43e-2)" "unprognostic (1.62e-2)" "unprognostic (2.63e-2)" "unprognostic (5.23e-2)" "unprognostic (2.04e-1)" "unprognostic (3.62e-1)" "unprognostic (3.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.66e-5)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (1.47e-1)" "unprognostic (7.02e-2)" 12.7 12.8 7.6 50.0 9.8 31.9 11.0 6.6 9.2 22.9 7.0 25.6 51.2 13.1 9.9 101.5 11.4 15.8 8.5 7.2 5.2 7.9 3.7 18.6 95.5 5.2 5.0 10.9 14.6 12.0 6.9 14.9 5.3 24.8 26.9 2.8 35.5 9.6 2.3 84.7 64.8 14.1 4.8 53.8 12.4 12.3 5.0 198.1 10.5 4.2 101.8 28.4 39.0 6.8 22.2 13.2 9.3 12.4 22.4 29.0 2.8 47.2 47.8 18.2 13.5 6.9 35.2 13.5 11.1 31.5 6.2 38.7 10.3 130.4 21.4 14.4 2.5 21.1 26.8 3.6 19.1 6.7 20.9 25.1 68.4 25.2 133.9 60.6 37.9 78.8 2.4 18.7 49.4 2.3 54.3 8.6 2.0 18.1 15.5 23.8 2.9 2.0 43.7 60.9 1.6 5.6 15.5 0.9 1.7 23.8 9.3 6.4 34.0 12.0 8.4 2.8 1.7 2.9 1.2 32.4 13.8 17.5 3.4 17.0 7.4 15.3 18.5 5.2 35.5 20.4 70.6 33.0 10.5 16.2 86.9 51.5 13.3 14.1 3.5 10.5 86.7 36.2 7.6 9.8 6.6 9.2 7.2 5.2 5.2 5.0 5.3 4.8 5.0 6.8 4.5 3.2 6.5 1.6 25.7 15.0 9.7 21.1 26.7 1.2 4.0 4.6 2.9 4.3 19.1 5.5 0.0 16.3 12.2 35.4 0.0 5.1 9.4 1.9 6.5 5.3 2.4 11.2 11.2 9.4 4.3 8.2 15.3 3.0 7.0 2.4 4.2 0.2 4.2 0.0 5.2 7.7 2.0 6.9 21.6 7.0 3.7 14.0 0.0 5.6 15.7 2.6 10.3 9.0 0.8 25.3 14.4 3.0 14.8 8.2 49.0 0.3 5.2 0.5 6.6 1.5 4.2 6.6 4.2 40.4 13.9 26.4 37.4 1.6 9.7 20.1 DGKE "DAGK6, DGK" ENSG00000153933 "Diacylglycerol kinase epsilon" P52429 17 56834107-56869567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 34.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 181.1;Cone photoreceptor cells: 189.7;Inhibitory neurons: 90.0;Rod photoreceptor cells: 165.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 84.8;MOLT-4: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017167 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA017167: AB_1847638" "unprognostic (1.19e-2)" "unprognostic (2.11e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.92e-5)" "unprognostic (4.20e-2)" "unprognostic (4.87e-2)" "unprognostic (3.37e-1)" "unprognostic (4.27e-2)" "unprognostic (1.19e-3)" "unprognostic (4.75e-2)" "unprognostic (6.07e-3)" "unprognostic (2.68e-1)" "unprognostic (2.55e-2)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.26e-1)" "unprognostic (3.69e-3)" 4.1 2.2 5.4 4.5 6.9 3.1 3.0 9.4 7.4 4.9 7.7 4.9 2.6 6.5 4.2 2.6 4.8 4.6 2.9 5.8 8.1 2.6 2.8 5.2 5.0 3.3 4.7 3.5 3.9 4.1 6.2 2.7 3.4 4.1 3.3 34.5 2.5 3.3 1.2 1.9 4.4 4.3 2.7 6.9 3.7 6.5 6.9 9.8 4.0 2.2 4.3 3.8 4.2 5.8 3.5 3.3 3.0 0.3 0.6 1.0 1.4 5.8 4.7 3.9 4.5 7.7 4.2 5.1 7.0 3.1 1.9 4.2 7.2 3.2 7.8 16.5 9.5 6.6 8.9 5.1 3.3 12.7 8.9 1.9 4.0 4.1 8.0 3.6 5.4 14.7 5.5 84.8 4.8 5.1 30.3 7.1 2.3 4.6 10.0 9.4 12.4 12.2 3.9 7.6 4.7 3.2 4.7 2.5 0.2 1.9 5.3 6.0 5.0 1.1 5.4 1.7 0.9 11.3 25.3 3.4 3.3 7.3 0.3 0.1 0.2 0.0 1.0 0.1 0.7 0.9 0.6 0.7 0.2 0.3 0.7 0.9 0.3 0.7 0.2 0.8 1.7 0.3 5.4 6.9 9.4 7.4 5.8 8.1 3.3 4.7 3.4 2.7 6.9 5.8 51.2 3.2 6.0 10.4 11.3 8.9 13.5 3.1 21.6 181.1 5.0 6.3 6.3 10.0 4.0 16.5 189.7 6.6 16.3 5.6 0.0 7.4 18.3 9.0 9.9 30.6 11.3 2.1 66.0 4.7 3.0 6.9 9.7 19.3 0.0 13.1 29.3 4.0 2.2 8.4 90.0 7.7 8.2 5.0 9.3 9.2 4.4 7.4 3.6 32.8 6.3 18.6 14.4 32.6 14.4 6.0 6.4 5.3 15.1 21.3 1.9 0.1 2.8 165.4 6.6 11.8 10.7 28.5 20.7 9.7 6.7 3.4 18.9 5.7 5.8 13.4 DHCR7 SLOS ENSG00000172893 "7-dehydrocholesterol reductase" Q9UBM7 11 71428193-71452868 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 77.9;Granulosa cells: 81.3;Hepatocytes: 156.1;Theca cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044280 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA044280: AB_10794893" "unprognostic (1.76e-1)" "unprognostic (1.50e-3)" "unprognostic (1.32e-2)" "unprognostic (7.16e-3)" "unprognostic (2.69e-1)" "unprognostic (2.18e-3)" "unprognostic (8.57e-3)" "unprognostic (3.02e-2)" "unprognostic (4.91e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-2)" "unprognostic (5.45e-2)" "prognostic favorable (6.93e-7)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "prognostic unfavorable (5.67e-4)" 23.7 97.2 28.1 13.0 35.4 46.7 36.3 42.4 37.0 16.2 15.6 21.1 48.1 10.6 59.2 42.2 12.5 8.9 28.8 28.8 35.8 16.3 161.1 21.8 6.0 55.3 38.8 54.4 16.6 24.4 18.4 8.3 55.8 21.6 14.4 8.7 27.8 7.1 13.6 68.2 19.3 9.9 34.4 9.6 19.1 31.0 38.0 4.7 11.9 13.2 9.4 7.9 22.7 58.9 126.4 112.3 106.7 118.9 49.0 75.8 33.7 50.9 134.1 43.1 114.5 419.8 401.5 87.1 79.0 48.6 376.2 235.9 128.8 276.7 44.5 33.5 98.7 33.4 89.3 183.1 127.8 63.7 15.6 89.2 122.1 159.3 108.4 34.6 63.8 112.7 159.6 180.7 43.2 341.1 52.4 72.6 154.1 124.9 67.4 46.9 150.6 377.3 162.3 187.3 144.7 53.9 48.4 157.6 113.9 51.4 153.2 34.5 60.4 11.5 62.4 3.7 61.5 59.3 78.7 95.8 33.8 110.9 48.9 5.6 2.1 1.9 10.5 1.4 12.6 6.5 8.9 9.8 2.8 5.4 11.0 13.0 1.1 5.8 1.5 7.1 6.0 6.9 28.1 35.4 42.4 37.0 28.8 35.8 55.3 38.8 55.8 34.4 38.0 58.9 7.1 3.2 19.1 7.2 7.1 0.8 10.1 77.9 3.4 8.4 21.8 14.9 13.1 15.7 39.2 22.0 12.5 15.5 11.9 9.9 7.9 36.9 0.1 3.9 1.5 11.8 9.5 5.2 3.2 49.9 27.6 12.8 11.7 9.3 0.0 81.3 7.9 156.1 11.9 0.0 4.5 12.3 54.9 3.8 3.3 1.7 8.4 5.6 5.4 1.0 5.8 21.2 4.1 5.0 14.7 26.7 11.5 4.9 10.0 16.5 8.9 3.8 7.6 8.7 13.1 3.9 9.0 0.5 7.0 11.9 1.1 54.2 13.8 103.6 15.0 9.5 DHRS2 "HEP27, SDR25C1" ENSG00000100867 "Dehydrogenase/reductase 2" Q13268 14 23630115-23645639 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 336.3;urinary bladder: 392.6" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 15.1;Syncytiotrophoblasts: 24.8;Theca cells: 12.6;Urothelial cells: 30.6" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 141.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 719.8;RT4: 828.1;SK-BR-3: 4047.2;U-2 OS: 1286.3" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "HPA053915, HPA069551" Enhanced Supported Nucleoplasm,Mitochondria No NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria Nucleoplasm "HPA053915: AB_2682307, HPA069551: AB_2686150" "unprognostic (3.07e-1)" "unprognostic (4.91e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (9.97e-2)" "unprognostic (5.03e-3)" "unprognostic (5.62e-2)" "unprognostic (1.86e-1)" "unprognostic (4.08e-1)" "unprognostic (6.91e-2)" "unprognostic (6.66e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (3.75e-5)" "unprognostic (1.83e-1)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "prognostic favorable (6.45e-4)" 1.2 1.6 0.3 0.1 0.2 0.0 336.3 0.2 0.4 1.9 0.2 0.2 0.0 0.2 0.4 0.1 0.3 0.0 0.0 0.4 1.2 1.6 23.6 0.2 0.0 0.4 1.2 25.5 10.3 2.1 2.5 3.2 1.7 3.3 0.4 0.4 97.7 3.1 0.0 3.4 0.1 0.2 0.3 19.0 4.7 3.4 1.1 0.0 0.1 0.0 0.0 392.6 13.6 0.3 1.2 2.2 0.2 199.9 0.3 0.3 3.1 0.3 0.2 6.4 0.1 14.4 1.1 0.8 1.9 0.3 10.4 2.0 0.7 1.2 1.4 289.5 21.6 2.8 1.0 719.8 0.0 4.3 25.1 1.7 0.2 2.5 1.7 0.0 0.1 0.4 1.8 0.7 1.4 8.0 2.5 0.3 1.1 6.9 31.7 2.6 6.3 2.7 0.0 828.1 3.5 5.0 5.9 4047.2 4.9 0.7 3.9 1.0 0.0 2.4 1286.3 7.7 4.3 2.0 0.6 11.3 1.7 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.4 0.4 1.2 0.4 1.2 1.7 0.3 1.1 0.3 0.1 0.0 0.0 0.0 0.4 0.0 2.1 0.2 0.0 0.8 7.4 1.3 0.4 0.0 0.0 0.0 0.0 7.9 0.1 0.1 7.9 0.1 5.0 0.1 0.0 0.2 3.5 0.0 0.1 0.2 15.1 3.5 0.0 0.0 0.0 1.4 0.0 4.9 1.7 0.0 0.1 0.2 0.0 0.3 0.8 3.7 0.0 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 4.8 0.2 1.2 0.0 0.3 0.0 0.2 0.0 1.2 6.6 0.0 0.7 0.3 7.4 0.0 0.1 24.8 0.2 12.6 0.7 30.6 DHRS9 "3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4" ENSG00000073737 "Dehydrogenase/reductase 9" Q9BPW9 2 169064789-169096167 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.9;intestine: 70.4" "Cell type enhanced" "Detected in many" "Club cells: 229.3;Distal enterocytes: 261.2;Early spermatids: 153.2;Paneth cells: 299.9;Respiratory ciliated cells: 155.9;Syncytiotrophoblasts: 267.5;Urothelial cells: 249.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 258.3;eosinophil: 99.2;neutrophil: 77.3" "Lineage enriched" "Detected in many" 10 "granulocytes: 258.3" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 22.8;HUVEC TERT2: 21.5;NB-4: 33.7;THP-1: 98.0;TIME: 49.9;U-2197: 31.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036491, HPA036667" Approved "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036491: AB_10673498, HPA036667: AB_10670237" "unprognostic (1.15e-1)" "unprognostic (3.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (4.80e-2)" "unprognostic (2.35e-1)" "unprognostic (3.24e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (3.62e-4)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.72e-1)" "unprognostic (3.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-1)" 10.0 0.2 2.2 12.5 2.4 8.5 5.1 3.0 2.6 8.6 1.6 70.4 1.9 1.2 0.9 28.2 1.0 5.7 53.9 2.5 2.3 0.3 3.1 7.1 20.2 4.2 3.2 0.7 0.4 0.2 0.4 2.8 4.3 0.8 46.2 1.2 6.1 0.5 0.3 3.3 5.7 4.2 3.8 7.6 10.8 11.3 3.2 2.2 0.3 0.8 26.8 17.5 10.1 4.5 0.0 0.7 0.0 0.0 2.5 10.2 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.0 6.5 1.7 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 8.9 1.0 0.4 0.5 1.3 6.1 22.8 21.5 0.0 1.0 0.0 0.0 0.0 0.1 33.7 0.0 0.3 8.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 98.0 49.9 0.1 0.2 31.4 0.2 0.1 0.0 0.0 0.8 18.9 0.0 258.3 21.0 99.2 0.0 25.0 0.6 6.5 0.0 0.0 21.6 5.0 0.1 0.0 77.3 0.4 5.1 1.6 0.0 5.9 2.2 2.4 3.0 2.6 2.5 2.3 4.2 3.2 4.3 3.8 3.2 4.5 0.3 0.0 1.3 0.0 1.4 1.7 19.3 72.4 0.0 0.0 0.1 0.4 24.4 0.0 229.3 0.0 0.0 2.5 0.0 261.2 0.0 4.6 153.2 0.5 0.0 0.6 1.8 0.8 0.2 25.3 1.3 1.5 7.7 0.1 91.0 0.0 0.0 0.6 25.0 0.0 0.2 51.6 36.7 10.2 38.8 45.5 1.2 16.6 0.0 19.7 3.5 3.9 0.0 0.0 0.2 68.6 299.9 0.4 6.4 6.5 1.5 0.1 155.9 0.1 6.6 0.2 10.9 1.1 0.6 0.3 1.4 267.5 3.8 0.0 8.2 249.2 DIAPH3 "AN, AUNA1, DRF3, FLJ34705, NSDAN" ENSG00000139734 "Diaphanous related formin 3" Q9NSV4 13 59665583-60163928 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;testis: 18.9" "Cell type enriched" "Detected in many" 5 "Early spermatids: 414.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032151 Supported "Plasma membrane,Microtubules" NA Yes "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Microtubules" "HPA032151: AB_2674181" "unprognostic (3.78e-2)" "unprognostic (1.28e-2)" "prognostic favorable (9.04e-4)" "prognostic unfavorable (4.18e-4)" "unprognostic (2.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.27e-4)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.74e-2)" "unprognostic (2.19e-1)" "unprognostic (5.22e-5)" "unprognostic (3.59e-3)" "unprognostic (5.31e-5)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-3)" 0.4 0.1 0.1 1.7 0.2 7.1 0.8 0.3 0.3 0.3 0.2 1.9 1.9 0.6 0.0 2.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 1.2 2.4 0.2 0.3 0.1 0.2 0.1 0.0 3.5 0.2 0.1 2.1 0.0 0.5 0.0 0.0 1.3 1.6 2.6 0.1 0.5 1.6 18.9 0.3 5.4 0.1 0.0 2.4 0.6 0.7 0.2 47.7 15.6 15.8 9.1 2.7 7.1 26.9 65.0 28.7 64.2 55.6 41.7 31.4 15.9 5.2 33.4 16.7 31.7 26.0 25.5 96.9 18.0 17.9 22.7 37.6 9.5 4.1 31.2 17.4 2.8 0.6 39.2 26.3 16.3 29.2 14.0 17.8 21.9 61.8 6.9 28.0 10.2 14.7 22.5 8.9 18.8 38.9 12.9 19.9 9.6 8.3 14.3 33.2 22.8 9.5 33.8 16.7 16.8 29.3 40.5 25.9 13.7 54.5 14.7 17.1 24.4 10.9 15.2 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.2 0.6 54.5 3.4 39.8 1.9 3.7 0.8 2.1 2.8 0.0 3.9 1.5 1.0 2.8 1.8 0.0 0.0 21.1 1.1 3.8 5.9 1.3 414.4 2.5 3.5 2.1 0.0 26.7 5.6 4.0 30.7 5.8 9.7 9.3 0.0 78.8 1.8 0.4 6.1 0.0 3.3 2.6 2.0 1.0 1.2 56.0 0.6 1.5 0.0 5.6 0.1 3.5 2.1 19.1 1.8 1.5 0.2 0.0 18.9 0.4 1.1 5.4 0.2 0.0 0.0 0.0 7.9 39.2 17.8 11.6 1.1 7.3 2.2 2.8 5.6 1.5 DIP2B "FLJ34278, KIAA1463" ENSG00000066084 "Disco interacting protein 2 homolog B" Q9P265 12 50504985-50748657 "Human disease related genes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 61.4" "Cell type enhanced" "Detected in many" "Microglial cells: 188.3;Oligodendrocyte precursor cells: 144.8;Oligodendrocytes: 634.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038472, HPA046133, HPA056045" Enhanced Approved "Endoplasmic reticulum" No No "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Endoplasmic reticulum" "HPA038472: AB_2676033, HPA046133: AB_2679551, HPA056045: AB_2683019" "prognostic unfavorable (2.60e-4)" "unprognostic (2.85e-2)" "unprognostic (3.67e-3)" "unprognostic (2.86e-2)" "unprognostic (9.56e-2)" "unprognostic (2.45e-1)" "unprognostic (1.69e-2)" "unprognostic (3.90e-2)" "unprognostic (1.94e-2)" "unprognostic (2.67e-2)" "unprognostic (9.57e-3)" "unprognostic (3.90e-2)" "unprognostic (4.29e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.60e-2)" "unprognostic (1.70e-3)" 6.6 8.7 22.8 8.9 46.0 12.1 10.5 35.0 28.2 7.1 6.9 9.5 6.2 6.2 3.4 14.6 4.3 7.0 5.7 22.5 31.0 6.0 11.3 6.7 9.9 36.1 40.0 9.3 7.6 11.0 6.1 10.3 38.0 6.5 10.7 16.4 8.5 4.1 5.1 17.3 6.5 7.1 26.4 14.9 6.9 7.6 37.0 12.9 8.2 6.3 11.7 7.3 8.8 61.4 20.0 12.0 17.9 12.6 10.0 9.7 25.0 11.3 13.1 10.6 8.0 21.8 11.0 13.4 13.4 12.4 10.9 20.5 28.8 21.1 12.6 15.9 10.7 21.3 10.1 27.6 15.7 25.7 12.4 11.0 18.1 11.8 17.1 18.6 20.4 12.0 30.3 12.5 9.4 15.7 19.9 12.9 10.2 11.4 22.0 23.4 17.6 6.4 12.0 15.5 16.9 11.8 28.3 16.4 17.3 20.6 23.0 17.7 21.6 8.6 10.1 7.9 9.3 9.0 16.0 15.4 11.9 11.7 12.0 1.0 1.2 2.7 0.4 1.4 0.6 1.4 0.9 0.3 1.4 2.2 1.6 1.3 4.9 0.5 3.9 0.4 1.0 0.7 22.8 46.0 35.0 28.2 22.5 31.0 36.1 40.0 38.0 26.4 37.0 61.4 15.4 6.4 10.5 74.1 26.3 54.9 30.2 14.7 12.5 31.5 15.0 11.4 9.0 17.2 10.5 9.2 64.6 13.3 9.2 25.2 0.0 10.9 1.4 14.3 12.9 15.5 31.3 13.7 121.1 17.4 17.6 11.2 20.4 15.1 10.8 25.0 15.0 18.2 20.4 11.8 125.3 18.3 10.2 37.4 15.7 3.3 10.2 24.5 16.0 188.3 18.7 14.4 11.3 144.8 634.8 22.0 14.0 10.1 15.4 28.1 8.4 6.7 8.8 31.9 0.0 8.0 10.0 12.4 17.7 34.6 66.9 38.0 13.3 34.3 12.4 24.4 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DKK1 "DKK-1, SK" ENSG00000107984 "Dickkopf WNT signaling pathway inhibitor 1" O94907 10 52314281-52318042 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.0;placenta: 48.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 486.2;Endometrial stromal cells: 337.6;Pancreatic endocrine cells: 194.6;Prostatic glandular cells: 992.9;Urothelial cells: 320.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1141.1;BJ hTERT+: 620.0;CACO-2: 1011.3;fHDF/TERT166: 1590.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.65e-2)" "unprognostic (4.21e-2)" "unprognostic (7.09e-2)" "unprognostic (7.99e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.35e-8)" "unprognostic (7.93e-2)" "prognostic unfavorable (7.80e-6)" "unprognostic (1.54e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.81e-1)" "unprognostic (1.68e-1)" "unprognostic (7.47e-3)" "unprognostic (4.05e-1)" "unprognostic (1.19e-1)" "unprognostic (2.06e-2)" 22.0 0.3 0.6 0.3 0.8 0.0 5.6 1.1 0.9 34.0 0.4 0.3 0.1 1.8 0.0 7.9 0.4 3.9 0.7 0.5 1.5 0.6 0.2 1.2 0.4 0.6 1.6 1.0 0.2 0.1 0.1 48.9 0.8 4.8 0.1 7.0 2.3 1.9 0.3 16.5 0.2 0.2 0.7 0.8 1.2 0.2 1.7 0.0 0.3 0.0 0.5 21.9 10.6 0.6 315.3 215.8 0.1 32.4 149.6 30.4 0.1 1141.1 620.0 383.8 202.5 1011.3 64.2 0.0 1.6 1590.5 93.5 245.1 0.3 130.7 361.3 0.1 0.7 0.0 4.4 26.2 31.8 0.0 0.1 30.3 16.0 83.0 488.3 19.8 35.8 0.0 0.0 0.1 255.8 135.7 0.0 0.1 0.2 13.7 543.9 0.2 34.8 0.0 148.6 25.6 0.2 342.4 102.8 1.1 17.7 0.4 1.1 0.9 78.9 0.2 0.2 338.5 211.9 0.1 0.3 0.1 4.6 0.1 37.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.1 0.9 0.5 1.5 0.6 1.6 0.8 0.7 1.7 0.6 1.9 25.6 0.0 0.0 1.0 5.4 486.2 28.5 0.0 0.2 0.8 6.9 1.1 0.0 15.2 0.0 0.0 4.6 0.0 0.9 0.0 10.7 1.2 11.0 337.6 8.5 0.0 0.0 1.2 4.1 4.0 91.5 2.6 8.1 4.5 0.0 1.1 0.0 9.3 0.0 2.2 2.4 6.1 0.0 1.6 0.6 0.0 4.9 0.0 1.0 0.0 6.1 0.0 1.5 0.2 194.6 5.0 0.0 1.3 992.9 0.4 0.0 9.8 0.4 0.0 0.0 10.6 0.4 2.2 1.4 3.1 8.3 2.8 0.0 1.0 320.0 DLG2 "chapsyn-110, PPP1R58, PSD-93, PSD93" ENSG00000150672 "Discs large MAGUK scaffold protein 2" Q15700 11 83455012-85627922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3292.3;Inhibitory neurons: 2602.7;Oligodendrocyte precursor cells: 2331.8;Oligodendrocytes: 4213.8" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 8.2;SH-SY5Y: 8.1;T-47d: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021307, HPA023896, CAB072341" Enhanced Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "CAB072341: , HPA021307: AB_1846625, HPA023896: AB_2671353" "unprognostic (2.61e-3)" "unprognostic (2.81e-2)" "unprognostic (4.05e-2)" "unprognostic (9.03e-2)" "unprognostic (3.25e-1)" "unprognostic (1.09e-1)" "unprognostic (9.44e-3)" "unprognostic (7.78e-2)" "unprognostic (4.32e-1)" "unprognostic (4.61e-2)" "unprognostic (9.28e-3)" "unprognostic (4.84e-1)" "unprognostic (7.66e-6)" "unprognostic (2.92e-2)" "unprognostic (2.41e-1)" "unprognostic (6.52e-2)" "unprognostic (8.89e-2)" 1.6 11.0 29.5 1.1 48.7 0.3 2.1 3.6 55.8 1.8 0.0 2.3 1.2 2.9 4.1 7.5 5.7 2.1 3.0 64.4 18.1 3.6 2.8 1.7 1.1 13.5 8.2 5.7 3.3 7.3 10.0 2.4 10.3 4.0 1.4 25.4 3.1 4.6 0.8 20.2 1.2 2.2 11.9 2.5 1.5 8.1 10.5 7.3 15.5 0.7 2.9 1.7 2.6 88.4 0.6 0.3 0.9 0.5 0.6 0.7 8.2 0.2 0.5 0.4 0.3 7.4 1.1 1.3 1.3 0.4 0.5 0.8 2.3 0.7 0.4 0.8 0.9 1.3 5.0 0.2 0.1 0.4 1.1 0.5 0.5 1.0 1.0 0.4 0.5 1.9 1.2 3.5 0.7 0.9 0.6 1.3 6.0 0.8 1.3 1.4 2.0 0.9 0.4 0.3 5.9 8.1 0.8 5.1 0.4 7.2 21.2 0.0 0.3 2.2 1.8 2.1 0.3 0.8 2.9 5.6 0.8 0.7 0.2 0.0 0.0 0.2 0.1 0.0 0.5 0.1 0.1 0.2 0.0 0.6 0.6 0.2 0.0 0.0 0.1 0.5 0.0 0.0 29.5 48.7 3.6 55.8 64.4 18.1 13.5 8.2 10.3 11.9 10.5 88.4 7.0 3.2 10.4 742.8 1.3 3.3 3.6 0.3 9.1 298.1 4.4 5.2 8.3 2.8 1.8 7.3 275.2 7.9 1.8 1.5 9.8 0.7 21.5 1.3 2.7 3.6 4.2 0.0 3292.3 0.4 0.5 7.4 1.1 2.4 0.0 1.6 2.2 4.6 4.0 23.5 2602.7 1.1 0.0 0.3 0.0 16.4 7.8 0.8 1.8 487.2 0.6 11.0 0.0 2331.8 4213.8 0.4 0.1 6.4 0.1 2.0 0.6 2.7 0.9 48.2 6.6 7.1 4.1 11.3 3.2 6.2 8.5 2.1 1.7 12.1 0.9 0.8 DLG4 "PSD-95, PSD95, SAP-90, SAP90" ENSG00000132535 "Discs large MAGUK scaffold protein 4" P78352 17 7187187-7219841 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 112.4;pituitary gland: 62.8;retina: 223.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.8;Cone photoreceptor cells: 102.2;Rod photoreceptor cells: 62.6" "Cancer enhanced" "Detected in all" "glioma: 13.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 40.0;hTERT-RPE1: 45.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001999, CAB002000, HPA010122, HPA071006" Enhanced "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB001999: , CAB002000: , HPA010122: AB_1855169, HPA071006: " "unprognostic (7.08e-2)" "unprognostic (1.06e-2)" "unprognostic (3.50e-3)" "unprognostic (2.48e-2)" "unprognostic (3.23e-2)" "unprognostic (1.80e-1)" "unprognostic (7.18e-3)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (2.72e-2)" "prognostic favorable (8.82e-6)" "unprognostic (3.45e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.12e-2)" "unprognostic (2.83e-2)" "unprognostic (3.68e-2)" "unprognostic (4.77e-3)" 13.1 19.1 41.9 9.3 49.6 3.6 10.0 32.1 112.4 23.5 0.0 18.5 4.9 23.1 6.9 6.3 20.7 10.8 19.6 86.3 17.5 10.3 7.1 14.7 4.4 7.2 0.4 30.3 6.3 7.2 62.8 8.9 5.6 16.6 3.5 223.2 7.2 12.8 6.1 4.7 8.4 11.1 0.0 13.9 10.3 18.9 7.7 8.7 11.0 2.8 2.9 13.3 16.4 36.2 0.5 15.2 29.4 9.1 8.4 14.6 1.5 14.1 12.5 10.8 11.3 0.7 4.0 2.4 6.4 12.1 1.6 1.8 1.1 6.7 3.3 17.6 6.0 9.4 35.1 1.4 8.0 0.3 40.0 17.5 0.9 7.7 11.0 45.5 11.5 10.1 3.1 10.1 15.2 1.0 9.3 5.1 3.8 0.8 1.6 10.5 1.6 1.0 6.6 0.3 12.4 10.5 0.4 0.8 2.6 7.0 6.5 7.2 16.4 30.6 12.6 7.4 7.8 1.5 0.9 2.1 19.3 6.9 8.5 0.4 0.2 0.1 0.2 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.4 0.0 0.1 41.9 49.6 32.1 112.4 86.3 17.5 7.2 0.4 5.6 0.0 7.7 36.2 3.4 0.0 1.5 14.0 1.5 2.7 2.2 1.8 6.2 41.8 4.8 3.7 3.2 1.5 2.2 3.7 102.2 0.6 3.3 0.4 0.0 0.9 1.8 2.4 9.5 7.0 15.0 0.8 22.8 0.2 0.4 5.5 2.0 3.2 7.0 3.4 10.0 2.2 3.9 20.2 17.5 0.8 4.1 11.0 10.3 1.3 7.2 7.8 3.6 8.4 5.5 11.1 0.0 4.5 4.2 0.2 0.1 10.1 0.2 1.7 1.3 0.3 3.0 62.6 0.0 1.4 4.5 6.5 2.9 3.2 1.8 0.5 1.1 6.8 0.5 1.1 DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191608 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 29.7;lymphoid tissue: 42.0;testis: 17.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 92.6;Extravillous trophoblasts: 23.1;Plasma cells: 22.1;Spermatocytes: 68.1;Spermatogonia: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 5.4" "Lineage enriched" "Detected in many" 5 "T-cells: 5.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA005546 Enhanced Supported "Centriolar satellite,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centriolar satellite, Cytosol" "HPA005546: AB_1078677" "unprognostic (2.24e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-3)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.42e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.52e-6)" "prognostic unfavorable (7.85e-4)" "unprognostic (6.15e-3)" "unprognostic (3.55e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.06e-2)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.93e-2)" 0.8 0.3 1.4 8.1 0.9 29.7 1.4 0.4 1.8 0.8 0.6 5.5 5.0 1.3 0.1 5.2 0.4 0.8 0.2 1.0 1.7 0.2 0.7 0.7 17.9 0.7 1.0 0.2 0.1 0.2 0.0 4.1 0.8 0.2 6.7 0.1 0.8 0.1 0.1 3.1 4.6 2.7 0.3 2.6 3.0 17.4 1.1 42.0 0.4 0.0 18.7 2.0 1.5 3.8 144.8 56.8 140.6 63.7 3.3 13.4 43.8 80.3 52.7 115.3 109.3 45.9 75.8 82.1 44.2 46.9 47.4 85.6 91.5 64.0 150.5 101.9 45.7 84.4 49.9 39.3 0.4 82.7 49.3 2.8 2.2 54.8 27.0 18.9 129.0 82.5 70.5 79.8 109.3 69.2 105.0 42.7 72.6 63.3 57.3 80.8 137.9 39.0 37.9 45.2 71.7 40.7 84.8 31.7 30.8 60.6 71.6 31.6 49.6 52.4 133.3 50.6 94.6 19.4 44.9 108.9 35.9 59.6 83.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.9 1.4 0.3 0.0 0.2 0.1 0.2 1.0 0.0 0.0 5.4 0.7 1.4 0.9 0.4 1.8 1.0 1.7 0.7 1.0 0.8 0.3 1.1 3.8 0.1 0.0 0.5 0.0 4.4 1.1 0.7 3.3 0.0 0.0 1.2 0.9 0.4 0.0 1.3 0.0 0.0 11.6 1.4 3.2 0.0 0.4 19.7 7.2 2.6 2.4 0.0 92.6 0.3 0.0 23.1 4.2 7.7 4.5 0.0 15.8 3.9 0.5 10.5 0.0 0.3 3.6 8.2 4.1 1.6 6.0 0.9 3.7 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.2 1.2 22.1 0.6 0.3 0.1 1.3 0.0 6.6 0.0 3.8 68.1 31.7 11.6 0.4 1.9 4.0 0.9 6.9 1.4 DLX2 TES-1 ENSG00000115844 "Distal-less homeobox 2" Q07687 2 172099438-172102900 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 3.0" "Cell type enhanced" "Detected in some" "dendritic cells: 6.5;Early spermatids: 6.9;Gastric mucus-secreting cells: 5.6;Inhibitory neurons: 10.0;Melanocytes: 5.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "hypothalamus: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "AN3-CA: 79.7;HEK 293: 50.8" "Region enhanced" "Detected in many" "olfactory bulb: 29.4" "Region enriched" "Detected in many" 5 "olfactory bulb: 23.2" HPA056965 Approved "Nuclear speckles" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA056965: AB_2683291" "unprognostic (8.12e-2)" "unprognostic (3.56e-1)" "unprognostic (2.48e-2)" "unprognostic (1.28e-2)" "unprognostic (4.07e-1)" "unprognostic (2.13e-1)" "unprognostic (8.60e-3)" "unprognostic (3.03e-2)" "unprognostic (2.41e-1)" "unprognostic (8.74e-2)" "unprognostic (3.53e-2)" "unprognostic (3.01e-1)" "unprognostic (6.69e-10)" "unprognostic (9.38e-2)" "unprognostic (2.47e-1)" "unprognostic (2.41e-1)" "unprognostic (7.95e-3)" 0.0 0.3 1.4 0.0 1.1 0.1 0.2 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 79.7 0.5 0.3 2.2 4.3 1.0 0.7 0.2 0.5 0.2 0.0 2.4 2.0 3.8 4.1 2.6 0.3 0.2 0.1 50.8 1.3 8.8 2.0 0.2 0.4 0.3 0.0 3.7 0.1 0.5 0.3 0.0 2.0 0.6 0.0 0.5 0.2 0.1 0.6 0.1 0.0 1.1 0.0 0.4 0.0 0.1 0.1 2.8 0.0 2.1 1.2 5.0 1.3 0.6 0.4 0.4 5.5 0.0 3.0 0.5 0.1 0.1 0.5 4.7 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.1 0.0 0.9 0.4 3.0 0.0 0.0 0.0 0.0 0.5 0.1 1.4 0.0 0.0 0.0 1.3 1.8 0.2 0.9 0.6 0.0 3.1 3.6 0.4 0.0 0.2 0.0 0.0 0.4 6.5 1.0 0.0 0.0 6.9 1.6 0.3 0.5 0.0 0.0 0.1 0.0 0.3 0.2 5.6 1.1 0.0 0.0 0.0 0.0 0.5 0.0 10.0 1.1 0.0 0.0 0.3 0.1 0.0 1.8 5.4 1.0 0.0 0.2 0.0 0.0 0.1 0.0 1.2 0.0 0.4 0.1 1.3 0.0 0.1 0.0 0.0 0.3 1.5 0.9 0.7 1.6 0.0 0.4 1.5 0.2 0.6 0.0 DLX5 ENSG00000105880 "Distal-less homeobox 5" P56178 7 97020396-97024950 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 14.1;placenta: 11.7;skin 1: 21.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 168.9;Endometrial ciliated cells: 217.8;Extravillous trophoblasts: 245.2;Glandular and luminal cells: 191.2;Syncytiotrophoblasts: 314.8" "Cancer enriched" "Detected in many" 11 "endometrial cancer: 81.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 53.7;HAP1: 27.2;SuSa: 13.4" "Group enriched" "Detected in many" 4 "basal ganglia: 13.5;olfactory bulb: 29.8" "Group enriched" "Detected in many" 4 "basal ganglia: 7.5;olfactory bulb: 18.0" HPA005670 Approved Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA005670: AB_1078681" "unprognostic (3.99e-1)" "unprognostic (1.05e-1)" "unprognostic (2.96e-2)" "unprognostic (1.31e-3)" "unprognostic (1.76e-1)" "unprognostic (2.86e-2)" "unprognostic (6.14e-2)" "unprognostic (2.46e-2)" "unprognostic (5.89e-2)" "unprognostic (6.20e-2)" "unprognostic (1.52e-1)" "unprognostic (1.01e-2)" "unprognostic (7.43e-8)" "unprognostic (1.39e-2)" "unprognostic (3.73e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" 1.5 0.3 2.1 0.2 3.9 0.0 0.9 0.2 3.4 7.6 0.4 0.6 0.3 14.1 1.0 1.9 1.3 0.4 0.5 1.5 4.5 0.5 0.0 0.2 1.7 0.2 0.3 1.6 0.0 0.2 0.8 11.7 0.3 1.7 0.0 0.0 3.3 2.8 0.3 21.2 0.1 0.9 0.3 0.1 0.1 0.9 1.5 1.8 1.5 0.0 2.1 0.7 3.0 1.3 0.0 0.0 0.0 8.2 0.0 0.0 53.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 6.2 27.2 0.0 0.0 0.0 4.6 0.0 0.6 0.4 0.0 0.0 0.0 0.1 8.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.0 3.6 1.5 2.1 0.2 0.0 0.0 13.4 0.0 0.0 0.0 1.7 0.3 0.4 0.0 0.0 0.0 0.0 3.2 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 3.9 0.2 3.4 1.5 4.5 0.2 0.3 0.3 0.3 1.5 1.3 1.4 0.0 0.0 0.0 0.0 9.8 1.1 1.7 0.6 0.0 0.3 0.6 0.2 0.0 0.1 0.0 0.0 168.9 0.0 0.0 0.0 0.0 0.2 217.8 13.3 2.9 0.0 0.0 0.1 0.0 245.2 1.5 0.0 191.2 0.0 1.6 0.0 0.0 16.9 0.0 12.8 0.0 0.0 0.0 1.1 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.1 59.2 0.2 8.0 4.2 11.6 7.9 20.6 314.8 1.6 0.1 0.0 1.6 DLX6 ENSG00000006377 "Distal-less homeobox 6" P56179 7 97005553-97011040 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.3;testis: 5.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 32.9;Early spermatids: 22.6;Endometrial ciliated cells: 37.3;Extravillous trophoblasts: 70.4;Glandular and luminal cells: 27.5;Syncytiotrophoblasts: 17.4" "Cancer enriched" "Detected in many" 8 "endometrial cancer: 12.5" "Region enhanced" "Detected in many" "basal ganglia: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 33.4;HAP1: 15.3;SH-SY5Y: 11.0;SuSa: 19.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory bulb: 27.0" "HPA030608, HPA061460" Uncertain Approved "Nuclear bodies" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nuclear bodies" "HPA030608: AB_10600867, HPA061460: AB_2684529" "unprognostic (7.50e-2)" "unprognostic (1.91e-1)" "unprognostic (5.19e-2)" "unprognostic (8.06e-2)" "unprognostic (8.16e-2)" "unprognostic (3.05e-1)" "unprognostic (4.32e-2)" "unprognostic (2.51e-1)" "unprognostic (2.86e-1)" "unprognostic (6.56e-2)" "unprognostic (8.09e-2)" "unprognostic (1.12e-7)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (5.58e-2)" "unprognostic (8.12e-2)" 0.4 0.0 2.1 0.0 7.3 0.3 0.1 0.0 4.3 2.0 0.0 0.2 0.0 2.5 0.8 0.0 0.4 0.0 0.1 0.8 4.7 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 3.0 0.0 0.3 0.0 0.0 1.1 0.9 0.1 1.5 0.0 0.2 0.0 0.1 0.0 5.5 1.2 0.3 0.4 0.1 0.2 0.3 0.2 0.4 0.0 0.0 0.0 10.1 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 6.1 0.0 0.0 1.9 15.3 0.0 0.0 0.0 3.9 0.0 5.9 7.1 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 2.6 1.6 0.0 0.0 0.0 0.0 2.2 7.3 11.0 1.0 0.0 0.3 19.3 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.9 1.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 7.3 0.0 4.3 0.8 4.7 0.0 0.0 0.0 0.0 1.2 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 32.9 0.1 0.0 0.0 0.0 22.6 37.3 2.2 0.2 0.0 0.0 0.0 0.0 70.4 0.2 0.0 27.5 0.0 0.0 0.0 0.0 3.3 0.0 8.0 0.0 0.0 0.0 0.0 3.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.8 6.8 10.2 0.0 0.0 17.4 0.3 0.0 0.0 0.1 DMBX1 "OTX3, PAXB" ENSG00000197587 "Diencephalon/mesencephalon homeobox 1" Q8NFW5 1 46489836-46516216 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 7.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.3;Cone photoreceptor cells: 2.1;Spermatogonia: 2.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 12.1;CAPAN-2: 4.0;GAMG: 3.1;K-562: 4.0;SiHa: 4.1;T-47d: 3.1" "Group enriched" "Detected in some" 7 "midbrain: 1.5;pons and medulla: 1.0" "Region enhanced" "Detected in some" "thalamus: 4.0" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.14e-2)" "unprognostic (2.33e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (7.13e-5)" "unprognostic (2.33e-2)" "unprognostic (8.92e-3)" "unprognostic (1.07e-1)" "unprognostic (5.90e-2)" "unprognostic (2.63e-2)" "unprognostic (1.89e-1)" "unprognostic (2.00e-4)" "unprognostic (1.19e-2)" "unprognostic (2.12e-12)" "unprognostic (7.91e-2)" "unprognostic (1.38e-1)" "unprognostic (1.98e-1)" "unprognostic (3.35e-2)" 0.0 0.0 1.7 0.0 0.0 0.1 0.1 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.9 2.8 0.0 0.0 0.1 0.7 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 7.2 0.0 0.2 0.0 0.0 0.2 0.0 0.2 1.8 1.0 0.0 12.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 4.0 0.0 0.6 0.0 3.1 1.0 2.3 0.0 0.0 0.8 1.3 0.0 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 1.2 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 4.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.0 2.7 0.1 0.0 0.8 0.9 2.8 0.6 0.0 7.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.3 0.0 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.6 2.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 DMTN "DMT, EPB49" ENSG00000158856 "Dematin actin binding protein" Q08495 8 22048995-22082527 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 192.5" "Cell type enriched" "Detected in many" 5 "Erythroid cells: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 3.8;memory CD8 T-cell: 1.6;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.5;neutrophil: 1.2;T-reg: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;T-cells: 3.8" "Cell line enhanced" "Detected in many" "A549: 68.9;HEL: 225.9;Hep G2: 63.9;HMC-1: 65.6;OE19: 67.3;RPTEC TERT1: 87.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024290, HPA058487" Uncertain NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA024290: AB_1847601, HPA058487: " "unprognostic (6.74e-2)" "unprognostic (1.51e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-3)" "prognostic unfavorable (7.92e-5)" "unprognostic (2.88e-1)" "unprognostic (3.85e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-2)" "unprognostic (2.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.97e-1)" "prognostic favorable (3.85e-9)" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (1.86e-1)" "unprognostic (8.07e-2)" 35.7 29.8 104.2 6.1 134.6 136.6 21.8 0.0 192.5 13.5 0.0 33.1 9.2 15.3 14.4 18.9 30.4 13.5 71.5 142.1 36.9 67.5 28.2 20.1 3.4 27.0 14.0 3.4 29.6 54.9 109.6 7.4 27.1 25.0 15.2 23.0 22.9 20.4 66.4 24.3 14.0 14.0 0.0 19.3 23.8 11.7 32.4 3.0 39.1 41.4 3.7 12.9 12.4 90.5 44.1 68.9 0.5 1.4 1.1 0.3 5.4 4.6 4.3 14.5 4.3 29.9 26.7 0.4 43.8 0.8 0.9 14.8 2.1 2.7 6.5 0.4 13.0 225.9 5.3 63.9 1.3 0.1 65.6 0.7 29.3 0.2 0.3 8.5 14.7 2.0 21.7 2.2 0.1 18.9 5.7 0.5 1.8 67.3 6.1 0.0 0.6 3.1 87.2 12.3 15.6 21.8 7.3 0.9 3.2 3.5 11.2 2.2 26.1 0.0 22.0 0.3 24.0 0.1 0.2 0.7 0.3 0.2 15.4 0.0 0.1 0.2 1.7 0.0 1.7 0.0 3.8 1.6 0.1 0.0 1.5 1.5 1.2 0.0 0.0 0.3 3.3 9.3 104.2 134.6 0.0 192.5 142.1 36.9 27.0 14.0 27.1 0.0 32.4 90.5 9.3 3.2 10.7 10.7 1.5 2.3 4.0 3.9 1.2 34.6 9.9 5.7 37.8 0.0 5.1 7.3 12.5 0.1 2.7 15.3 19.6 11.4 12.7 11.2 1.7 10.2 20.5 248.6 45.7 11.4 1.7 2.4 7.7 12.7 0.0 4.1 3.9 15.8 0.5 28.6 29.7 8.7 0.0 1.0 1.6 7.7 0.3 44.5 14.2 5.6 1.3 2.6 0.0 1.5 4.3 18.2 10.0 2.6 1.4 3.7 1.8 29.6 9.3 7.3 0.0 1.4 5.7 1.4 2.4 3.8 5.7 0.1 6.4 0.3 13.3 4.8 DNAAF3 "C19orf51, CILD2, FLJ36139, FLJ40069, PCD, PF22" ENSG00000167646 "Dynein axonemal assembly factor 3" Q8N9W5 19 55158661-55166722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 40.8;testis: 65.4" "Group enriched" "Detected in many" 5 "Early spermatids: 395.2;Late spermatids: 722.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 26.2;HEL: 31.6;K-562: 25.3;U-937: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056220 Approved "Nuclear bodies,Mitochondria" No No "Cluster 49: Ciliated cells - Cilium organization" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Nuclear bodies" "HPA056220: AB_2683071" "unprognostic (1.71e-2)" "unprognostic (2.67e-2)" "unprognostic (6.10e-2)" "unprognostic (9.93e-3)" "unprognostic (1.77e-1)" "unprognostic (1.87e-1)" "unprognostic (2.22e-2)" "unprognostic (1.82e-1)" "unprognostic (5.36e-2)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (1.83e-5)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (2.35e-2)" "unprognostic (8.03e-2)" 0.4 1.8 1.5 0.0 1.2 0.0 0.6 0.9 0.7 2.5 6.1 0.3 0.1 0.9 3.4 0.6 40.8 0.6 5.0 1.5 2.3 2.7 0.6 4.3 0.1 4.0 8.2 0.2 1.6 3.5 0.7 0.1 4.7 0.3 0.1 0.4 0.4 0.9 0.1 0.9 0.3 0.2 3.1 0.3 0.3 65.4 1.5 0.5 2.3 0.0 0.1 0.1 0.4 2.1 8.8 6.6 0.6 6.7 0.1 0.0 0.6 0.1 0.2 1.0 0.7 0.3 4.0 10.5 2.5 0.3 1.9 10.1 1.5 3.0 0.4 0.0 26.2 31.6 0.5 0.5 0.2 13.6 3.1 0.2 4.0 1.7 2.2 0.9 0.5 4.7 25.3 13.9 0.4 5.9 0.4 0.3 0.5 9.5 15.0 16.5 1.0 3.2 5.4 0.2 0.8 2.6 1.1 1.1 1.6 0.2 8.3 0.4 1.0 0.8 3.9 4.0 0.2 0.4 2.5 0.6 4.9 18.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.2 0.9 0.7 1.5 2.3 4.0 8.2 4.7 3.1 1.5 2.1 0.2 0.0 0.5 0.0 0.0 3.2 0.0 4.7 4.6 0.0 1.1 0.6 3.0 1.5 7.5 7.3 0.0 0.0 0.0 0.3 7.9 2.7 395.2 55.8 0.5 0.6 0.0 0.0 0.5 1.0 0.1 1.2 0.0 1.3 0.0 1.9 0.7 0.4 0.2 0.0 0.5 0.5 12.2 0.0 0.4 722.0 4.4 4.2 0.0 0.0 0.0 2.1 0.0 0.5 0.1 0.2 0.1 3.0 0.0 0.1 0.0 5.1 75.2 0.0 0.0 0.0 2.3 104.8 18.6 0.3 1.3 0.0 0.1 1.1 0.4 0.2 DNAH2 "DNHD3, FLJ46675, KIAA1503" ENSG00000183914 "Dynein axonemal heavy chain 2" Q9P225 17 7717354-7833744 "Predicted intracellular proteins, Predicted membrane proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 13.1;parathyroid gland: 10.5;retina: 21.1" "Group enriched" "Detected in many" 4 "Respiratory ciliated cells: 43.0;Rod photoreceptor cells: 123.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.6;CACO-2: 4.0;CAPAN-2: 2.4;OE19: 1.8;SCLC-21H: 2.3;SiHa: 2.3" "Low region specificity" "Detected in some" HPA067103 Enhanced Approved Microtubules NA NA "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Microtubules "HPA067103: AB_2685778" "unprognostic (2.03e-2)" "unprognostic (1.79e-2)" "unprognostic (2.23e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" "unprognostic (2.51e-1)" "unprognostic (1.35e-1)" "unprognostic (7.50e-3)" "unprognostic (1.29e-2)" "unprognostic (8.28e-2)" "unprognostic (2.51e-3)" "unprognostic (1.74e-1)" "unprognostic (2.06e-2)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (8.74e-3)" "unprognostic (4.60e-2)" 0.4 0.1 1.5 0.1 2.4 0.5 0.5 1.0 1.1 1.2 7.1 0.2 0.2 0.5 1.6 0.1 13.1 0.4 0.1 1.8 1.1 0.1 0.4 1.9 0.1 5.6 6.8 2.5 0.5 10.5 0.4 1.7 2.8 0.3 0.2 21.1 0.1 0.0 0.1 0.2 0.1 0.2 3.5 0.2 0.2 6.5 1.1 0.3 0.3 0.0 0.1 0.2 0.1 1.8 2.6 0.1 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 4.0 2.4 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.1 0.0 0.3 0.1 0.6 0.1 0.1 0.2 0.0 0.4 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.5 0.1 0.2 0.2 1.8 0.8 0.1 0.2 0.0 0.0 0.7 2.3 0.1 2.3 0.0 1.2 0.2 0.2 0.1 0.1 0.2 0.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.6 0.1 0.0 0.1 0.0 0.0 1.5 2.4 1.0 1.1 1.8 1.1 5.6 6.8 2.8 3.5 1.1 1.8 1.1 0.0 1.1 1.3 0.7 0.3 1.0 1.7 0.0 2.7 0.6 1.0 1.9 0.0 3.6 0.0 2.1 0.0 0.0 0.0 0.0 0.4 6.2 20.2 0.6 1.2 6.7 0.0 6.1 0.0 0.0 0.8 0.0 0.8 0.0 2.3 0.4 0.1 0.1 1.7 4.9 0.5 8.2 0.3 0.7 2.3 0.3 0.2 0.0 1.0 0.0 4.6 0.0 3.0 2.1 0.1 1.1 0.0 0.0 0.7 0.0 0.4 43.0 123.9 0.0 1.0 1.0 9.6 2.6 0.0 0.1 0.0 0.2 0.5 0.2 0.9 DNAH3 "DKFZp434N074, DLP3, Dnahc3b, Hsadhc3" ENSG00000158486 "Dynein axonemal heavy chain 3" Q8TD57 16 20933111-21159441 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;fallopian tube: 5.1;testis: 4.3" "Cell type enhanced" "Detected in some" "Early spermatids: 42.7;Endometrial ciliated cells: 31.0;Late spermatids: 17.1;Respiratory ciliated cells: 77.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062493 Approved "Nuclear membrane,Intermediate filaments" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear membrane" "Intermediate filaments" "HPA062493: " "unprognostic (1.68e-1)" "unprognostic (9.84e-2)" "unprognostic (1.32e-1)" "unprognostic (2.11e-3)" "unprognostic (1.25e-2)" "unprognostic (5.23e-2)" "unprognostic (1.40e-3)" "unprognostic (1.79e-1)" "unprognostic (7.50e-2)" "unprognostic (1.75e-1)" "unprognostic (2.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.57e-5)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (1.92e-1)" "unprognostic (1.15e-1)" 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.4 0.1 0.0 0.1 0.0 0.0 5.1 0.0 0.0 0.4 0.5 0.0 0.0 1.2 0.0 2.2 2.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 4.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.4 0.5 2.2 2.1 1.4 1.5 0.5 0.5 0.0 0.0 1.1 0.7 0.0 0.3 0.7 2.0 0.0 0.0 0.1 0.1 1.7 0.0 6.3 0.0 0.0 0.3 0.0 2.0 0.0 0.0 42.7 31.0 0.2 0.3 0.0 0.0 2.9 0.0 0.1 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 3.6 1.3 0.0 0.0 0.0 17.1 0.0 0.1 0.0 0.0 1.0 0.0 0.0 2.5 1.7 0.0 0.8 0.0 0.0 0.5 1.3 0.0 77.8 0.0 0.0 0.2 1.0 0.9 8.8 0.5 0.6 0.0 0.1 0.0 1.9 0.3 DNAH5 "CILD3, Dnahc5, HL1, KTGNR, PCD" ENSG00000039139 "Dynein axonemal heavy chain 5" Q8TE73 5 13690328-14011818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;choroid plexus: 14.0" "Cell type enhanced" "Detected in many" "Club cells: 61.7;Endometrial ciliated cells: 190.3;Respiratory ciliated cells: 258.7" "Cancer enhanced" "Detected in many" "prostate cancer: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;LHCN-M2: 1.1;PC-3: 2.7;RPTEC TERT1: 1.3;TIME: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA037469, HPA037470" Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA037469: AB_10672791, HPA037470: AB_10672348" "unprognostic (3.85e-1)" "unprognostic (8.17e-2)" "unprognostic (5.94e-2)" "unprognostic (1.12e-1)" "unprognostic (4.58e-3)" "unprognostic (6.23e-2)" "unprognostic (3.33e-3)" "unprognostic (2.86e-2)" "unprognostic (9.94e-2)" "unprognostic (4.39e-2)" "unprognostic (1.59e-1)" "unprognostic (9.99e-2)" "unprognostic (9.97e-3)" "unprognostic (8.87e-2)" "unprognostic (8.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.65e-1)" 0.0 0.1 0.9 0.0 1.1 0.0 1.5 0.5 0.3 0.3 14.0 0.1 0.0 0.1 0.1 0.0 3.8 0.1 0.0 1.0 1.7 0.8 1.0 1.7 0.0 4.2 6.7 0.0 0.9 0.0 2.0 0.0 4.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 0.3 1.8 0.0 1.1 0.0 0.0 0.8 0.0 1.4 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.1 0.0 0.5 0.0 0.5 0.2 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.3 0.4 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.5 0.3 1.0 1.7 4.2 6.7 4.0 2.1 1.8 1.4 0.3 3.2 24.4 7.2 0.2 0.0 1.7 5.6 0.0 0.0 11.7 7.0 1.5 14.3 61.7 5.5 0.0 0.0 0.1 0.0 0.0 6.7 7.3 190.3 1.9 1.2 1.8 0.0 12.9 3.6 0.2 1.8 0.0 12.4 2.5 0.0 0.0 10.9 0.0 0.0 7.8 0.0 6.1 0.0 0.0 5.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 4.0 0.4 2.6 0.0 0.0 0.1 14.8 0.0 4.3 258.7 0.0 0.0 1.6 2.6 2.6 3.6 0.0 0.0 0.0 0.4 0.1 0.0 3.8 DNAJA4 PRO1472 ENSG00000140403 "DnaJ heat shock protein family (Hsp40) member A4" Q8WW22 15 78264086-78282196 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 138.4;tongue: 144.6" "Group enriched" "Detected in many" 5 "Early spermatids: 673.9;Late spermatids: 1608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 33.6;CAPAN-2: 43.3;HeLa: 47.3;MCF7: 33.6;RT4: 85.2;SCLC-21H: 53.3;SiHa: 42.7;THP-1: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004646, HPA041790" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "CAB004646: AB_426011, HPA041790: AB_2677674" "unprognostic (8.41e-2)" "unprognostic (2.48e-1)" "unprognostic (3.00e-2)" "unprognostic (8.20e-3)" "unprognostic (1.14e-3)" "unprognostic (1.99e-1)" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.86e-2)" "unprognostic (7.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.08e-7)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (9.01e-2)" "unprognostic (2.93e-2)" 16.5 20.0 60.6 14.0 67.7 63.7 12.6 62.6 138.4 14.1 45.6 18.0 13.8 8.3 20.2 15.8 38.9 11.2 123.3 68.6 93.1 26.7 3.3 19.7 11.3 65.7 73.3 12.1 6.6 7.4 30.9 9.5 89.8 26.7 18.5 33.0 15.6 15.6 123.2 28.6 16.3 19.6 59.8 13.5 24.2 78.3 73.5 9.4 9.6 144.6 12.4 29.6 13.6 71.3 33.6 0.2 0.0 0.0 0.0 0.0 0.1 4.1 0.0 1.1 0.5 0.0 43.3 0.0 0.3 3.2 0.0 31.3 0.0 0.0 0.1 0.1 0.0 19.9 47.3 0.0 9.4 0.0 20.6 3.6 4.1 2.6 0.0 0.0 6.6 0.0 0.0 0.0 0.4 33.6 0.0 0.0 0.0 14.4 0.3 0.0 0.0 0.0 0.1 85.2 53.3 0.0 42.7 8.6 3.6 2.3 32.4 39.8 0.5 0.0 8.7 4.0 0.4 0.6 2.4 0.0 0.1 4.2 0.0 0.0 0.3 1.1 0.6 0.3 1.0 0.7 0.9 0.9 0.4 0.1 1.7 1.4 0.0 0.1 0.4 0.2 0.5 0.6 60.6 67.7 62.6 138.4 68.6 93.1 65.7 73.3 89.8 59.8 73.5 71.3 41.9 6.4 4.8 12.7 10.0 28.8 209.9 14.0 2.2 19.6 44.6 29.2 43.6 2.8 33.5 7.3 81.3 1.9 6.7 55.5 1.9 1.3 673.9 124.0 11.4 18.9 100.3 92.8 16.6 2.4 3.8 18.3 21.4 41.8 36.9 7.5 6.8 0.2 16.5 6.7 24.0 34.9 10.2 9.5 81.7 1608.0 10.2 51.7 51.6 6.5 3.5 10.3 6.2 15.1 19.0 5.1 55.3 11.3 3.7 115.8 15.8 7.2 138.9 22.6 6.6 17.4 20.2 33.8 27.7 16.9 46.7 6.8 37.1 6.9 42.1 190.1 DNAJB2 "CMT2T, HSJ1, HSPF3" ENSG00000135924 "DnaJ heat shock protein family (Hsp40) member B2" P25686 2 219279342-219286898 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 366.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036268 Approved Enhanced "Nuclear membrane" NA NA 9900 "Cluster 52: Eosinophils - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear membrane" "HPA036268: AB_10670793" "unprognostic (2.02e-2)" "unprognostic (3.69e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (2.53e-2)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.45e-3)" "unprognostic (5.11e-2)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.16e-3)" "unprognostic (7.03e-2)" "unprognostic (4.09e-2)" "unprognostic (4.64e-2)" "unprognostic (1.96e-2)" "unprognostic (5.98e-2)" "unprognostic (5.62e-3)" 41.9 106.9 264.5 17.7 290.6 26.6 45.7 276.0 323.5 63.8 232.0 48.9 23.2 46.2 45.2 54.1 48.2 26.6 85.4 266.6 270.7 81.0 72.1 45.8 26.0 281.8 281.8 65.0 84.8 54.3 112.1 27.1 279.7 73.9 15.8 63.9 62.3 35.5 135.6 108.1 36.0 15.8 269.7 46.7 54.8 86.0 280.5 28.4 71.0 56.5 20.5 52.8 59.0 366.0 34.9 14.2 21.9 20.7 45.6 22.1 29.3 32.8 27.2 29.0 24.2 66.2 21.3 21.4 39.7 31.6 66.3 49.1 27.9 36.3 16.3 45.3 12.2 41.7 28.0 32.0 30.8 7.1 36.5 21.3 103.3 31.8 38.4 51.3 12.9 23.5 7.4 23.7 21.4 18.0 13.0 8.4 12.9 30.2 26.4 13.4 17.9 13.5 31.7 24.5 20.6 26.0 38.0 38.4 64.9 57.5 28.6 14.9 17.5 41.6 82.3 12.0 28.6 26.2 8.4 35.0 42.8 6.5 31.1 0.0 0.4 2.1 0.7 0.4 0.6 0.5 0.7 0.6 0.2 1.7 1.0 0.9 0.4 1.3 1.2 0.6 1.0 0.4 264.5 290.6 276.0 323.5 266.6 270.7 281.8 281.8 279.7 269.7 280.5 366.0 24.6 19.2 31.4 35.6 30.9 28.6 40.9 17.1 9.1 97.9 61.9 33.9 77.4 25.8 18.0 38.6 56.3 36.1 24.0 41.5 78.2 60.0 43.8 43.5 16.2 22.3 53.7 69.9 17.9 33.5 34.7 27.5 22.4 27.9 24.8 22.1 20.7 20.5 28.2 80.8 26.5 47.5 10.2 19.7 28.2 70.9 36.4 28.0 32.0 11.2 21.6 84.8 15.5 16.6 144.2 68.9 23.6 39.1 28.5 39.8 31.7 56.5 39.0 87.3 19.7 27.3 28.3 56.5 20.6 18.9 50.4 69.0 30.2 23.1 25.5 25.8 DNER "bet, UNQ26" ENSG00000187957 "Delta/notch like EGF repeat containing" Q8NFT8 2 229357629-229714555 "Cancer-related genes, Predicted membrane proteins" "Notch signaling pathway" "Activator, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 73.0;brain: 147.5;choroid plexus: 143.8" "Group enriched" "Detected in many" 4 "Bipolar cells: 123.3;Inhibitory neurons: 333.0;Oligodendrocyte precursor cells: 435.8;Oligodendrocytes: 247.7" "Cancer enriched" "Detected in many" 32 "glioma: 73.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "GAMG: 368.0;hTERT-HME1: 149.7;hTERT-RPE1: 409.5;U-138 MG: 252.2;U-87 MG: 149.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017320 Enhanced NA NA 7900000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA017320: AB_1847808" "unprognostic (4.39e-2)" "unprognostic (1.83e-1)" "unprognostic (3.25e-1)" "unprognostic (1.00e-3)" "unprognostic (8.73e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.23e-3)" "unprognostic (2.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.60e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.42e-4)" "unprognostic (2.59e-2)" "unprognostic (7.32e-2)" "unprognostic (5.63e-2)" "unprognostic (5.13e-3)" 2.0 73.0 88.3 1.3 121.0 0.0 2.3 139.7 82.9 2.0 143.8 5.2 0.4 2.8 5.7 0.3 4.1 0.2 11.8 72.3 130.9 11.2 0.1 1.0 0.3 121.3 121.0 0.6 0.9 8.9 30.3 0.4 117.8 1.9 1.1 60.5 43.4 0.4 0.8 10.3 1.6 1.2 124.7 0.1 10.7 1.0 147.5 0.5 0.1 0.5 1.2 0.8 1.1 137.2 0.4 1.9 3.9 0.3 0.6 0.5 0.0 0.2 1.4 8.6 2.6 0.0 1.1 0.0 0.4 0.1 368.0 0.1 0.3 1.2 4.3 0.0 0.1 0.0 12.4 0.0 1.4 0.0 0.1 2.6 9.3 6.5 149.7 409.5 0.0 0.0 0.0 0.3 2.3 0.1 0.0 0.0 2.5 0.2 14.0 0.1 1.6 0.0 14.6 0.0 30.3 2.5 0.8 0.1 0.8 0.4 0.1 0.0 0.0 252.2 0.0 8.5 39.7 0.0 0.0 0.0 149.6 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 88.3 121.0 139.7 82.9 72.3 130.9 121.3 121.0 117.8 124.7 147.5 137.2 0.1 0.0 0.0 68.9 0.0 0.4 5.9 1.9 1.8 123.3 1.6 0.6 12.2 0.0 1.4 3.7 14.6 0.0 0.0 0.0 1.9 0.2 7.3 4.1 1.5 0.6 28.7 0.0 24.1 1.3 0.2 4.3 0.0 6.7 0.0 1.6 0.0 0.0 0.1 11.8 333.0 0.0 6.1 0.0 0.8 1.9 5.9 0.9 19.6 8.4 0.1 52.0 0.0 435.8 247.7 0.3 0.0 6.0 0.0 4.5 0.0 1.2 34.1 55.0 0.0 0.1 0.8 1.2 1.1 0.5 0.0 0.1 0.2 0.6 0.1 0.5 DNMBP "ARHGEF36, KIAA1010, Tuba" ENSG00000107554 "Dynamin binding protein" Q6XZF7 10 99875577-100009947 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037878, HPA058216" Uncertain Approved "Nucleoli,Nuclear bodies,Golgi apparatus,Cytosol" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoli, Golgi apparatus, Cytosol" "Nuclear bodies" "HPA037878: AB_10675622, HPA058216: AB_2683640" "unprognostic (3.25e-1)" "unprognostic (8.19e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.95e-6)" "unprognostic (3.92e-2)" "unprognostic (4.13e-1)" "unprognostic (9.79e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.02e-1)" "unprognostic (8.67e-3)" "unprognostic (4.03e-2)" "unprognostic (5.07e-3)" "unprognostic (6.52e-2)" "unprognostic (4.95e-2)" "unprognostic (1.28e-1)" "prognostic favorable (6.15e-4)" 13.6 6.0 3.6 5.5 3.7 10.3 10.2 6.2 5.3 15.8 8.6 17.7 22.5 9.6 12.5 10.2 11.3 11.0 7.5 4.7 4.2 20.6 13.1 8.4 4.6 3.7 3.6 11.5 17.6 31.7 3.9 10.5 3.8 8.9 20.7 15.8 8.4 12.8 13.4 27.4 27.2 8.8 3.0 7.7 23.8 6.9 5.2 20.1 8.1 11.1 5.2 19.8 17.7 3.1 25.7 20.7 18.4 29.2 32.9 27.4 4.4 45.2 43.6 21.5 20.7 14.2 38.0 26.6 18.9 34.9 11.8 19.9 21.6 26.1 29.9 1.4 6.7 3.8 23.7 10.0 17.1 2.6 1.8 13.0 5.7 26.6 23.4 75.5 52.1 8.5 3.6 0.0 44.1 3.2 4.5 5.1 17.7 18.0 12.3 5.5 18.7 1.4 36.6 21.9 3.1 4.2 7.4 1.9 5.7 25.3 1.5 2.4 63.4 16.0 15.3 13.1 29.8 2.1 1.7 36.3 15.2 8.4 12.2 0.0 0.8 0.2 0.7 1.2 0.7 1.2 0.1 0.4 0.3 1.9 0.1 0.3 0.7 2.1 1.2 0.3 0.0 0.6 3.6 3.7 6.2 5.3 4.7 4.2 3.7 3.6 3.8 3.0 5.2 3.1 6.8 9.6 11.0 11.1 14.8 35.1 7.2 5.0 5.2 6.3 9.3 6.3 6.1 12.8 11.2 12.9 35.5 7.7 4.4 36.7 3.9 7.5 1.0 27.0 11.0 12.6 3.6 0.0 15.9 14.3 1.4 17.6 26.0 43.9 2.5 4.1 11.4 12.8 4.7 13.5 24.8 25.0 6.1 10.7 9.6 3.2 13.7 20.5 3.6 23.4 3.3 4.3 0.0 10.6 2.6 19.3 23.6 9.1 6.1 4.0 36.5 3.7 19.9 26.6 0.0 4.3 6.9 4.2 9.3 9.0 45.6 3.7 4.3 15.0 28.4 21.8 DOK5 "C20orf180, dJ805C22.1" ENSG00000101134 "Docking protein 5" Q9P104 20 54475593-54651169 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 46.0;tongue: 24.3" "Cell type enhanced" "Detected in many" "Astrocytes: 110.7;Distal tubular cells: 39.2;Excitatory neurons: 49.7;Horizontal cells: 38.7;Inhibitory neurons: 79.6;Muller glia cells: 63.9;Oligodendrocyte precursor cells: 58.3" "Group enriched" "Detected in many" 6 "glioma: 18.0;ovarian cancer: 29.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 32.9;ASC diff: 13.1;ASC TERT1: 11.0;hTEC/SVTERT24-B: 13.7;U-138 MG: 51.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054460, HPA065235" Uncertain Approved "Focal adhesion sites" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "HPA054460: AB_2682495, HPA065235: AB_2685441" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (8.90e-2)" "prognostic unfavorable (8.99e-7)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-4)" "unprognostic (5.12e-2)" "unprognostic (4.51e-3)" "unprognostic (2.97e-1)" "unprognostic (2.69e-2)" "unprognostic (1.49e-1)" "unprognostic (6.49e-2)" "unprognostic (4.23e-3)" "unprognostic (3.08e-1)" "unprognostic (4.56e-2)" "unprognostic (1.99e-2)" 2.9 1.9 14.6 1.7 14.2 0.0 1.9 13.4 15.6 1.1 13.0 1.4 0.3 1.7 0.3 1.7 12.2 9.8 18.4 15.4 16.9 5.2 2.3 1.0 0.6 15.9 14.7 0.9 1.2 0.2 1.1 1.8 18.6 0.9 0.7 11.7 1.4 0.8 46.0 0.5 0.7 2.8 13.9 0.3 0.8 1.7 15.3 0.4 5.1 24.3 0.4 4.7 0.9 13.3 0.0 0.0 32.9 0.0 13.1 11.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 5.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 4.3 0.0 13.7 0.0 0.6 1.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 3.6 7.0 0.0 8.6 0.0 0.0 0.1 0.4 1.9 0.0 0.0 0.0 51.3 3.2 1.4 0.0 0.0 0.0 0.1 2.3 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 14.2 13.4 15.6 15.4 16.9 15.9 14.7 18.6 13.9 15.3 13.3 4.8 0.0 0.0 110.7 0.3 0.3 2.3 0.0 0.0 12.3 6.7 6.2 7.3 12.8 0.0 11.0 6.2 0.3 0.1 0.0 39.2 17.7 2.3 0.4 1.5 3.3 0.0 0.0 49.7 1.2 0.6 14.4 0.0 10.6 0.0 28.6 17.5 0.0 29.0 38.7 79.6 0.0 0.0 0.6 2.5 4.5 2.5 0.6 0.0 9.4 14.5 63.9 0.0 58.3 2.1 2.2 0.0 1.2 0.1 2.0 0.0 0.2 0.0 8.1 0.0 2.8 5.3 3.7 1.5 0.0 0.4 0.8 0.2 1.6 0.0 0.9 DPCD "DKFZP566F084, RP11-529I10.4" ENSG00000166171 "Deleted in primary ciliary dyskinesia homolog (mouse)" Q9BVM2 10 101570560-101609662 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 132.4" "Group enriched" "Detected in many" 4 "Early spermatids: 579.4;Late spermatids: 1068.7;Respiratory ciliated cells: 329.7;Spermatocytes: 313.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 20.2;intermediate monocyte: 22.2;myeloid DC: 29.6;non-classical monocyte: 9.5" "Group enriched" "Detected in all" 14 "dendritic cells: 29.6;monocytes: 22.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036603, HPA036604" Enhanced Approved "Nuclear speckles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA036603: AB_2675212, HPA036604: AB_10673503" "unprognostic (1.22e-2)" "unprognostic (1.73e-3)" "unprognostic (4.66e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.90e-1)" "unprognostic (9.13e-2)" "unprognostic (4.00e-3)" "unprognostic (1.71e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (5.04e-2)" "unprognostic (3.83e-2)" "unprognostic (7.54e-2)" 10.5 18.7 35.1 8.7 37.2 11.8 19.4 31.5 42.0 21.8 55.1 17.3 6.8 16.7 41.3 20.4 73.3 15.5 29.6 37.4 39.1 30.9 10.4 14.0 6.2 36.2 37.1 23.5 14.7 49.3 49.5 10.6 36.5 16.1 13.5 55.8 21.2 15.7 19.2 13.2 7.1 18.0 33.3 4.5 14.4 132.4 39.7 6.6 33.0 18.3 8.2 14.4 14.9 33.4 97.1 53.4 37.9 77.2 35.2 61.7 15.6 44.5 53.6 59.4 55.1 38.8 51.4 9.0 74.6 42.7 25.2 54.0 55.4 65.3 61.2 23.0 57.5 11.3 49.8 56.7 20.3 58.8 8.1 42.3 54.8 72.0 56.1 153.7 50.8 14.0 32.4 12.6 45.1 122.9 0.0 48.1 28.7 26.9 41.6 0.0 51.8 20.5 92.6 25.3 37.1 63.3 36.5 23.4 31.3 34.1 71.2 23.9 35.5 27.3 24.9 55.7 62.3 37.9 45.9 16.9 94.7 13.7 11.7 0.0 20.2 1.0 1.8 22.2 1.7 1.3 1.4 1.4 29.6 0.7 1.5 1.8 0.9 1.6 9.5 4.1 0.6 8.1 35.1 37.2 31.5 42.0 37.4 39.1 36.2 37.1 36.5 33.3 39.7 33.4 6.9 35.3 12.4 4.9 2.1 9.7 29.5 89.2 9.6 16.4 25.4 29.5 33.7 30.0 56.6 49.7 18.8 24.6 0.9 10.5 95.9 63.3 579.4 136.5 23.5 11.1 23.9 14.1 7.7 27.5 16.7 21.2 10.2 20.2 1.3 19.2 11.4 10.9 24.0 11.8 6.2 12.5 52.9 4.4 14.6 1068.7 23.6 8.7 16.0 3.7 6.9 27.8 2.1 4.0 1.4 33.9 12.4 27.8 5.6 18.6 3.5 117.3 329.7 49.1 0.0 12.4 29.0 313.8 77.4 8.7 14.2 10.7 2.9 25.3 22.1 23.9 DPP10 "DPL2, DPPY, DPRP3" ENSG00000175497 "Dipeptidyl peptidase like 10" Q8N608 2 114442299-115845780 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 10.7;brain: 20.2;pancreas: 17.3" "Cell type enhanced" "Detected in many" "Astrocytes: 4634.9;Excitatory neurons: 3067.4;Inhibitory neurons: 3258.7;Oligodendrocyte precursor cells: 990.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.1;HAP1: 6.2;HMC-1: 4.3;JURKAT: 3.4;NTERA-2: 3.7;RT4: 6.7;SCLC-21H: 9.7;SH-SY5Y: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048767 Uncertain NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA048767: AB_2680515" "unprognostic (1.19e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (6.59e-2)" "unprognostic (2.92e-1)" "unprognostic (5.35e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (8.33e-2)" "unprognostic (7.61e-2)" "unprognostic (4.22e-2)" 0.2 10.7 12.4 0.3 20.2 0.1 0.0 0.0 16.6 0.3 0.0 2.2 1.2 0.4 0.0 0.0 0.1 0.8 0.1 19.3 0.5 0.2 0.1 0.2 0.0 1.9 3.1 0.0 17.3 0.0 0.8 0.8 2.0 0.0 2.8 4.1 0.2 0.0 0.0 0.1 1.2 0.8 4.5 0.0 1.0 1.0 6.0 0.0 0.6 0.0 0.0 0.3 0.0 11.7 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 6.7 9.7 3.9 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 20.2 0.0 16.6 19.3 0.5 1.9 3.1 2.0 4.5 6.0 11.7 0.0 0.0 0.0 4634.9 0.0 0.0 0.0 0.0 0.6 21.7 0.0 0.0 1.5 4.3 0.6 0.0 0.0 1.5 0.0 2.3 0.0 0.0 12.4 0.1 0.1 0.1 4.2 2.1 3067.4 2.7 10.2 0.5 0.0 0.3 0.0 5.8 0.7 0.0 0.3 5.0 3258.7 1.4 0.0 0.0 0.0 5.7 0.3 0.0 1.8 58.1 0.0 1.4 0.0 990.7 48.3 0.8 1.9 0.0 0.0 0.0 0.2 0.2 0.0 0.7 0.0 0.0 0.1 1.6 2.6 0.3 0.0 4.4 0.0 0.4 3.2 0.0 DPY19L2 "FLJ32949, SPATA34" ENSG00000177990 "Dpy-19 like 2" Q6NUT2 12 63558913-63668939 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.6" "Group enriched" "Detected in many" 4 "Early spermatids: 329.9;Excitatory neurons: 124.1;Inhibitory neurons: 137.2;Late spermatids: 363.0;Oligodendrocyte precursor cells: 124.1;Spermatocytes: 143.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 9.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA071264, HPA078305" Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 16: MAIT-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Mitochondria Nucleoplasm "HPA071264: AB_2686375, HPA078305: " "unprognostic (1.97e-1)" "unprognostic (4.08e-1)" "unprognostic (4.46e-3)" "unprognostic (2.50e-2)" "unprognostic (1.64e-1)" "unprognostic (1.17e-4)" "unprognostic (2.28e-2)" "unprognostic (2.14e-3)" "unprognostic (1.53e-1)" "unprognostic (3.64e-1)" "unprognostic (3.99e-3)" "unprognostic (1.97e-1)" "unprognostic (6.31e-3)" "unprognostic (4.22e-3)" "unprognostic (5.88e-2)" "unprognostic (8.90e-3)" "unprognostic (1.79e-1)" 6.7 5.3 4.0 0.5 3.9 3.0 4.7 7.0 6.9 11.4 6.6 5.2 0.6 7.8 4.1 1.4 6.4 2.8 19.2 3.0 4.3 12.7 0.2 1.3 0.9 2.4 3.0 11.0 2.7 9.0 10.5 1.2 1.5 9.3 1.3 14.4 1.6 4.7 0.5 1.6 1.7 3.5 0.8 1.7 2.9 65.6 3.3 0.7 13.1 0.6 0.6 6.3 5.1 4.2 1.0 2.6 2.2 5.4 0.6 0.0 0.2 1.8 1.8 2.4 3.1 0.4 0.8 2.8 1.8 0.7 2.9 0.4 2.7 0.3 3.6 1.5 1.7 4.6 1.4 1.7 0.5 3.4 1.4 1.5 0.1 1.1 0.0 6.1 0.8 2.2 1.9 2.9 3.9 1.7 0.2 1.4 2.1 0.4 2.4 0.0 1.8 0.0 4.6 0.5 7.0 0.7 0.6 0.2 1.0 0.9 1.9 0.9 0.5 3.2 4.2 0.5 4.6 7.5 9.3 0.0 3.4 1.6 3.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 4.0 3.9 7.0 6.9 3.0 4.3 2.4 3.0 1.5 0.8 3.3 4.2 6.7 3.2 0.0 23.2 0.2 0.5 2.9 0.1 2.2 49.6 1.9 1.8 32.3 1.5 3.8 12.9 14.6 2.0 0.3 0.1 5.9 0.4 329.9 5.6 7.1 1.7 0.0 7.2 124.1 0.0 1.3 2.2 0.5 2.1 2.5 1.2 1.4 0.1 0.3 3.3 137.2 0.1 6.1 0.0 0.4 363.0 7.2 0.4 7.2 11.2 0.1 9.2 0.0 124.1 5.0 0.2 0.0 8.6 0.5 2.9 0.0 6.4 11.6 6.7 26.3 3.8 19.9 143.3 4.9 0.2 0.4 1.4 0.8 3.6 0.1 1.1 DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1712.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" 22.2 13.2 7.2 22.6 12.8 10.3 16.7 5.7 10.4 18.8 2.4 11.9 21.9 14.9 8.4 17.1 14.3 25.7 8.9 7.4 12.9 12.6 68.5 29.6 16.6 12.4 9.4 24.0 11.8 9.2 6.2 4.5 12.1 9.9 10.1 3.3 15.0 13.4 5.8 7.1 19.4 18.2 6.9 24.7 8.4 3.7 12.9 17.0 10.3 10.1 12.0 18.2 14.2 24.4 22.2 6.2 7.8 0.2 42.4 72.5 0.1 35.2 31.9 32.1 23.6 0.0 9.2 11.7 50.6 32.9 5.1 5.2 0.0 8.3 58.7 11.6 7.3 10.0 11.1 0.2 18.8 4.5 0.6 57.5 3.0 25.7 29.3 67.7 26.8 6.8 0.4 36.4 17.0 0.0 23.6 6.4 0.9 0.2 7.5 0.1 37.1 18.6 39.4 0.1 11.1 8.8 30.1 2.5 0.3 0.8 0.0 10.2 30.9 69.2 5.0 56.4 70.6 3.0 0.1 0.2 10.2 12.6 56.2 18.2 61.1 4.1 11.6 29.5 14.8 2.2 13.3 11.0 32.7 4.9 12.5 11.1 59.8 13.3 27.1 0.9 15.8 21.9 7.2 12.8 5.7 10.4 7.4 12.9 12.4 9.4 12.1 6.9 12.9 24.4 25.5 16.0 39.1 23.8 15.4 7.6 8.8 9.4 18.8 2.5 8.4 8.3 5.3 40.0 11.5 7.3 0.0 0.2 19.2 3.3 5.9 2.5 7.0 1.5 15.2 14.7 3.0 13.3 258.6 6.4 0.2 30.0 10.7 1.7 9.5 4.5 17.2 54.2 17.1 0.0 30.5 5.5 6.1 130.4 27.0 4.0 33.5 73.7 3.6 105.9 98.1 4.8 27.8 34.2 1712.3 5.3 2.1 18.8 17.0 4.9 21.0 6.6 8.6 0.1 13.1 16.0 17.7 1.2 3.1 19.7 5.5 0.1 31.4 5.1 6.8 9.3 DQX1 FLJ23757 ENSG00000144045 "DEAQ-box RNA dependent ATPase 1" Q8TE96 2 74518131-74526281 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 16.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 17.3;Gastric mucus-secreting cells: 13.7;Intestinal goblet cells: 17.3;Paneth cells: 13.9;Proximal enterocytes: 44.2;Undifferentiated cells: 12.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HBEC3-KT: 5.8;Hep G2: 18.4;hTCEpi: 6.1;OE19: 15.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039158, HPA046763" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoli fibrillar center" "HPA039158: AB_10960125, HPA046763: " "unprognostic (2.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (9.95e-2)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-1)" "unprognostic (4.54e-2)" "unprognostic (1.68e-1)" "unprognostic (7.67e-2)" "unprognostic (2.21e-2)" "unprognostic (0.00e+0)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-3)" 0.0 0.0 0.1 0.6 0.1 0.0 0.1 0.0 0.2 0.4 0.0 6.3 16.4 0.0 0.0 1.6 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.0 5.6 0.0 0.4 0.0 0.0 1.1 13.9 0.5 0.0 0.1 3.2 0.0 0.1 0.0 0.0 0.0 1.0 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.6 0.1 5.8 0.1 0.0 0.0 0.5 0.2 18.4 0.0 0.2 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 15.5 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 0.0 2.4 0.0 0.9 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.5 0.5 0.1 4.5 4.6 0.4 0.1 0.0 0.3 1.5 3.5 0.0 2.1 1.6 0.0 17.3 0.0 0.0 0.0 0.2 0.1 0.0 2.4 0.0 0.6 0.0 0.8 0.6 13.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 17.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 13.9 0.0 0.4 0.0 44.2 0.0 5.0 0.9 0.0 0.1 0.1 0.6 0.3 3.1 0.0 1.1 0.1 0.0 12.5 0.2 DR1 "NC2-BETA, NC2B, NCB2" ENSG00000117505 "Down-regulator of transcription 1" Q01658 1 93345907-93369493 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050785, HPA055308" Enhanced Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA050785: AB_2681237, HPA055308: AB_2682779" "unprognostic (1.46e-1)" "unprognostic (9.62e-2)" "prognostic favorable (4.79e-4)" "unprognostic (1.03e-2)" "unprognostic (2.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.95e-7)" "unprognostic (8.70e-2)" "unprognostic (6.71e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.07e-1)" "unprognostic (2.29e-1)" "unprognostic (4.97e-1)" "unprognostic (1.60e-1)" 21.8 18.9 9.8 28.8 9.6 59.1 16.8 12.5 9.3 17.7 23.7 18.2 27.2 21.0 11.1 30.0 14.2 23.1 27.0 8.7 10.8 21.8 20.4 19.6 43.3 9.9 9.8 15.9 18.8 16.9 12.1 32.0 9.5 17.1 16.3 14.1 19.5 14.0 50.4 29.4 22.4 19.2 10.3 27.0 30.2 55.7 10.5 47.7 18.7 42.9 30.8 27.3 22.6 10.5 97.1 29.8 46.8 60.6 42.3 47.9 57.5 76.5 46.6 50.9 54.0 34.9 34.1 101.9 86.4 56.7 69.3 50.1 56.7 53.0 74.6 86.4 53.0 85.8 58.7 38.4 67.3 102.1 60.6 33.7 62.4 71.2 102.2 53.1 45.9 60.0 90.0 95.7 61.0 29.8 97.6 32.1 78.1 33.4 72.1 83.5 103.2 104.0 36.3 58.0 45.3 57.6 65.1 59.7 80.6 42.2 42.2 79.4 72.1 91.5 73.0 90.7 116.0 54.9 65.6 105.5 26.3 80.3 38.2 95.2 46.2 82.1 35.3 52.7 39.2 36.9 38.8 40.4 55.9 31.5 38.6 37.8 62.8 35.5 47.4 45.4 57.1 41.3 9.8 9.6 12.5 9.3 8.7 10.8 9.9 9.8 9.5 10.3 10.5 10.5 36.2 28.9 22.1 10.1 43.5 171.3 38.0 38.7 47.3 32.0 29.1 24.1 33.9 22.8 27.9 36.8 25.0 74.5 84.6 42.8 45.0 31.4 183.1 18.4 33.7 37.5 20.8 59.3 8.4 27.7 73.6 34.3 38.2 24.2 48.9 19.7 29.3 27.6 53.0 50.5 8.7 42.6 10.2 50.8 82.8 106.2 28.3 55.2 44.4 15.0 68.0 16.0 69.0 7.5 10.8 52.9 25.9 26.4 31.9 51.6 29.8 40.7 17.6 25.3 32.9 27.7 42.0 163.2 41.2 69.4 160.5 109.9 59.8 26.2 26.9 79.2 DSC1 CDHF1 ENSG00000134765 "Desmocollin 1" Q08554 18 31129236-31162856 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 228.8" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 166.5" "Group enriched" "Detected in some" 17 "head and neck cancer: 7.3;melanoma: 4.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 2.7;naive CD8 T-cell: 2.6" "Lineage enriched" "Detected in single" 8 "T-cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA075379 Enhanced NA NA 27000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA075379: AB_2732290" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.48e-2)" "unprognostic (3.71e-2)" "unprognostic (8.19e-3)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.27e-1)" "unprognostic (1.78e-1)" "unprognostic (5.65e-6)" "unprognostic (5.08e-2)" "unprognostic (2.91e-1)" "unprognostic (6.99e-2)" "unprognostic (4.74e-5)" 0.2 0.0 0.0 0.1 0.0 0.2 9.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 228.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 2.7 2.6 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 14.1 0.3 0.0 2.2 0.9 0.1 0.4 29.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.4 0.0 0.0 3.6 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.5 166.5 0.4 0.6 0.0 0.0 0.3 DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 164.0;vagina: 97.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 384.0;Paneth cells: 324.8;Squamous epithelial cells: 705.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 28.9;neutrophil: 8.1" "Lineage enriched" "Detected in many" 14 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "BEWO: 37.6;CAPAN-2: 48.3;HaCaT: 71.1;hTCEpi: 76.0;OE19: 60.7;SK-BR-3: 44.4;SuSa: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Plasma membrane,Cytosol" NA NA 24000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" 5.5 1.8 1.3 12.7 1.4 0.7 22.2 1.3 1.6 59.2 1.9 50.5 41.6 1.5 5.9 164.0 6.1 3.7 10.6 1.2 2.0 5.9 7.3 7.9 3.7 2.6 1.5 0.6 10.5 27.0 0.5 21.3 2.2 15.8 44.5 1.0 46.8 1.0 0.3 11.9 42.9 4.0 1.8 3.0 43.2 0.8 1.6 6.6 4.0 3.1 62.2 3.6 97.4 2.3 18.1 1.9 2.9 0.0 0.0 0.0 37.6 0.0 0.0 0.0 0.0 9.8 48.3 0.0 0.7 0.0 0.9 71.1 11.8 4.9 0.0 0.0 6.9 27.1 8.4 16.9 0.3 0.2 0.5 0.4 76.0 0.0 7.3 6.1 0.0 0.0 13.4 0.0 0.0 14.7 0.0 1.1 11.3 60.7 17.4 13.2 0.0 0.2 0.1 0.7 0.0 0.1 0.0 44.4 0.0 43.4 12.2 18.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 28.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.4 1.3 1.4 1.3 1.6 1.2 2.0 2.6 1.5 2.2 1.8 1.6 2.3 25.1 28.9 5.6 3.3 1.0 83.7 44.5 16.4 67.7 0.8 75.3 65.7 33.8 32.9 11.1 7.3 0.0 100.8 1.0 384.0 0.0 83.5 0.1 19.1 4.0 6.7 69.4 0.4 3.3 33.2 186.6 5.9 47.4 43.8 0.0 2.7 8.2 16.0 24.8 0.0 1.5 83.1 20.3 48.8 29.3 0.2 0.3 35.3 14.2 4.7 25.2 11.2 0.0 2.0 0.2 155.7 324.8 0.7 0.3 140.6 118.2 9.7 3.8 0.7 0.0 1.2 3.0 0.1 1.3 705.6 55.0 83.9 2.0 0.3 114.0 76.1 DSC3 "CDHF3, DSC, DSC1, DSC2, DSC4" ENSG00000134762 "Desmocollin 3" Q14574 18 30989365-31042815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 99.2;skin 1: 372.6" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 500.7;Basal squamous epithelial cells: 214.5;Squamous epithelial cells: 419.6;Suprabasal keratinocytes: 688.8" "Cancer enhanced" "Detected in many" "cervical cancer: 78.6;head and neck cancer: 107.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 246.2;HBEC3-KT: 54.6;hTCEpi: 156.7;hTERT-HME1: 103.6;REH: 44.8" "Region enhanced" "Detected in some" "hippocampal formation: 3.3" "CAB037328, HPA049265, HPA073937" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 6000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" "CAB037328: , HPA049265: AB_2680695, HPA073937: AB_2686645" "unprognostic (4.44e-3)" "unprognostic (6.28e-2)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (2.38e-1)" "unprognostic (1.32e-2)" "unprognostic (6.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-2)" "unprognostic (3.92e-3)" "unprognostic (3.13e-1)" "unprognostic (4.13e-4)" "unprognostic (1.22e-2)" "unprognostic (7.85e-2)" "unprognostic (3.47e-1)" "prognostic unfavorable (1.04e-5)" 4.8 0.1 0.1 0.5 0.0 0.2 12.5 0.1 0.0 23.8 0.0 0.3 0.4 0.1 1.2 99.2 1.3 0.0 0.4 0.1 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.4 0.2 3.4 0.2 12.5 0.0 6.0 0.1 0.1 19.6 1.3 1.0 372.6 0.3 0.5 0.0 0.0 0.1 0.1 0.0 7.7 0.1 0.0 24.7 3.5 48.5 0.0 17.2 1.8 0.2 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 246.2 0.0 54.6 0.0 0.1 14.6 0.9 4.7 0.4 9.7 0.1 0.2 10.2 156.7 0.0 103.6 19.6 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.9 0.1 21.8 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.1 0.3 0.0 500.7 62.0 49.5 214.5 0.0 3.1 8.0 1.3 0.0 30.3 0.0 0.0 73.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.3 2.4 0.0 0.3 0.0 14.2 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.3 0.0 0.3 0.2 12.2 0.0 34.8 0.0 0.0 0.6 39.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.2 32.1 0.0 0.1 10.2 0.0 0.0 0.0 3.4 0.1 0.1 419.6 688.8 25.0 2.3 0.0 0.1 89.1 DSCAM "CHD2-42, CHD2-52" ENSG00000171587 "DS cell adhesion molecule" O60469 21 40010999-40847158 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.6;pituitary gland: 4.2;retina: 1.9" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 4376.6" "Cancer enriched" "Detected in single" 14 "glioma: 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 3.6;MCF7: 8.3;NTERA-2: 2.2;SCLC-21H: 3.3;T-47d: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019324, HPA057493" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA019324: AB_2670118, HPA057493: " "unprognostic (1.47e-2)" "unprognostic (1.04e-1)" "unprognostic (7.59e-2)" "unprognostic (1.99e-2)" "unprognostic (9.98e-2)" "unprognostic (5.49e-4)" "unprognostic (1.78e-1)" "unprognostic (9.58e-2)" "unprognostic (7.95e-2)" "unprognostic (1.53e-1)" "unprognostic (8.85e-3)" "unprognostic (2.12e-2)" "unprognostic (2.00e-3)" "unprognostic (2.17e-2)" "unprognostic (2.29e-1)" "unprognostic (8.75e-2)" "unprognostic (5.46e-3)" 0.0 0.0 5.4 0.0 5.8 0.0 0.1 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 5.6 4.2 0.0 0.1 0.0 0.0 2.3 2.8 0.0 0.1 0.0 4.2 0.7 3.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.8 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.8 0.1 6.6 5.6 4.2 2.3 2.8 3.5 2.9 4.1 4.1 0.0 0.0 0.0 19.9 0.0 0.0 0.1 0.0 0.0 19.6 0.0 0.4 1.1 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.4 0.0 0.0 1083.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 16.8 649.1 0.0 0.0 2.4 0.0 4.2 0.0 0.0 0.0 200.5 0.0 0.7 0.0 4376.6 21.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 2.0 0.1 1.7 1.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 DSG1 "CDHF4, DSG" ENSG00000134760 "Desmoglein 1" Q02413 18 31318160-31359246 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 564.4" "Group enriched" "Detected in some" 25 "Basal keratinocytes: 117.4;Suprabasal keratinocytes: 315.7" "Group enriched" "Detected in many" 10 "head and neck cancer: 57.0;melanoma: 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 23 "hTCEpi: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022128, HPA074188" Enhanced NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "HPA022128: AB_1847620, HPA074188: " "unprognostic (2.55e-2)" "unprognostic (8.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (5.22e-1)" "unprognostic (1.81e-2)" "unprognostic (1.57e-2)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.99e-4)" 0.4 0.0 0.0 0.0 0.0 0.2 24.7 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.1 1.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.6 0.0 2.0 564.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 2.1 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.0 0.0 0.6 0.0 3.3 0.9 1.7 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.1 0.1 0.0 0.0 8.6 3.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.2 6.5 315.7 0.0 0.2 0.0 0.1 0.0 DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 460.7;skin 1: 854.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 902.0;Cardiomyocytes: 729.7;Squamous epithelial cells: 1657.5;Suprabasal keratinocytes: 2018.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 314.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 278.0;HaCaT: 302.6;HBEC3-KT: 217.5;hTCEpi: 666.3;SuSa: 204.1" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 9.5" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 100000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "CAB037324: , HPA045840: AB_2679468, HPA054950: AB_2682645" "unprognostic (1.65e-1)" "unprognostic (3.09e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.82e-2)" "unprognostic (7.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (5.02e-2)" "unprognostic (2.94e-2)" "prognostic favorable (1.53e-9)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.82e-4)" 5.2 11.6 4.2 7.0 1.8 0.6 65.8 2.5 3.5 151.0 19.3 46.0 52.0 5.4 27.5 460.7 16.3 7.8 84.9 3.4 0.9 22.4 41.9 6.1 3.7 1.6 2.0 2.0 111.5 54.9 9.0 63.3 1.5 29.9 43.5 21.2 125.1 11.7 3.4 854.8 42.3 2.9 2.4 3.2 48.1 1.5 2.2 37.1 41.5 0.6 78.7 13.1 286.1 0.9 132.2 38.9 0.0 0.1 5.6 8.2 278.0 25.5 21.8 12.4 12.0 110.8 33.5 0.1 35.8 40.9 10.0 302.6 46.1 217.5 2.2 0.1 54.1 0.0 21.5 149.5 0.0 0.6 0.9 1.9 666.3 11.0 121.7 30.0 0.0 0.6 0.2 0.2 22.0 61.4 0.1 1.0 5.6 62.6 19.6 0.1 0.1 32.9 45.3 34.8 12.6 0.3 28.5 59.9 0.2 204.1 71.0 0.3 0.0 4.8 1.2 0.3 0.3 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 1.8 2.5 3.5 3.4 0.9 1.6 2.0 1.5 2.4 2.2 0.9 7.6 51.3 17.0 0.0 7.5 902.0 164.5 157.3 278.3 4.4 184.5 126.4 729.7 97.2 197.5 60.7 14.6 273.0 1.2 357.1 1.9 160.6 1.8 306.5 42.4 46.9 174.6 0.0 0.1 111.9 273.1 51.2 237.0 560.1 3.8 532.2 4.6 186.6 27.5 0.0 0.9 204.7 111.9 1.9 77.8 1.3 0.9 5.9 101.4 3.7 2.6 14.7 0.0 0.0 0.1 167.4 284.2 0.0 5.7 204.0 180.7 12.0 176.6 28.6 0.0 0.4 67.4 1.3 2.7 1657.5 2018.0 385.7 8.1 0.3 247.8 269.9 DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 14.6;intestine: 4.7;lymphoid tissue: 14.2;placenta: 3.9;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 25.3;Erythroid cells: 36.2;Extravillous trophoblasts: 16.2;Spermatocytes: 53.2;Spermatogonia: 20.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028016, HPA032023, HPA032031" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA028016: AB_10611958, HPA032023: AB_2674114, HPA032031: AB_2674119" "unprognostic (7.61e-2)" "unprognostic (1.01e-3)" "unprognostic (2.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (8.96e-3)" "unprognostic (2.45e-3)" "unprognostic (8.83e-3)" "unprognostic (2.52e-3)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.71e-9)" "unprognostic (5.93e-2)" "unprognostic (2.01e-1)" "unprognostic (1.96e-2)" "unprognostic (2.82e-1)" 0.6 0.2 0.0 4.1 0.0 14.6 1.9 0.0 0.1 0.6 0.0 3.3 2.3 1.1 0.1 1.9 0.4 0.4 0.1 0.0 0.0 0.1 1.2 1.4 5.6 0.0 0.1 0.1 0.1 0.5 0.2 3.9 0.0 0.4 4.7 0.0 0.4 0.1 0.1 2.1 3.0 1.9 0.0 2.5 1.3 13.7 0.1 14.2 0.5 0.0 6.4 1.2 0.7 0.0 34.1 28.1 48.0 23.6 2.9 5.8 23.3 41.3 25.5 38.1 56.1 17.6 29.0 25.2 15.4 16.1 25.0 25.8 62.5 34.9 54.7 31.4 30.9 40.7 33.6 21.5 0.1 54.1 25.3 2.5 1.2 62.2 32.4 6.8 17.7 44.7 49.1 51.1 44.4 13.5 75.3 24.3 56.6 25.2 32.9 57.2 84.0 49.2 11.6 22.9 29.6 46.0 39.2 37.5 17.6 47.7 32.0 24.1 9.7 38.2 28.6 40.5 47.8 18.4 30.5 57.7 19.1 35.5 37.8 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.5 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.3 2.3 0.4 1.7 0.0 0.0 1.3 1.3 7.0 1.5 0.9 0.0 0.0 12.8 1.4 1.5 0.0 0.4 25.3 0.4 1.3 5.2 0.0 36.2 0.2 0.0 16.2 2.4 3.1 1.0 0.0 11.4 0.7 0.4 4.7 0.0 0.3 3.3 0.0 0.3 0.8 12.4 1.2 2.2 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.6 0.4 0.0 12.8 0.2 0.6 0.0 0.1 0.0 0.0 0.2 2.7 53.2 20.8 5.6 1.7 1.5 2.6 1.6 5.2 0.7 DTNB ENSG00000138101 "Dystrobrevin beta" O60941 2 25377198-25673647 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 36.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.8;Inhibitory neurons: 214.1;Oligodendrocyte precursor cells: 137.7;Oligodendrocytes: 343.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA061357 Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA061357: AB_2684489" "unprognostic (1.14e-1)" "unprognostic (1.39e-2)" "unprognostic (3.17e-2)" "unprognostic (7.40e-2)" "unprognostic (1.17e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.78e-2)" "unprognostic (3.67e-3)" "unprognostic (3.98e-2)" "unprognostic (9.45e-2)" "unprognostic (4.67e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.16e-2)" "unprognostic (6.49e-2)" 2.1 2.1 7.8 1.6 6.7 2.9 9.7 3.4 12.1 4.2 0.0 1.7 1.2 2.8 10.1 4.5 4.6 3.3 2.0 12.4 3.6 4.2 3.4 4.3 2.5 4.9 1.7 4.4 7.7 9.9 5.8 1.9 4.5 8.4 1.0 5.0 36.0 5.1 2.7 4.5 1.6 1.2 0.1 2.7 5.6 6.7 2.9 4.0 11.1 1.5 1.9 3.5 4.0 5.6 10.7 9.1 6.6 7.5 4.0 5.2 0.2 3.2 4.2 4.0 5.3 3.5 2.6 5.5 1.3 2.5 5.0 3.7 4.6 13.1 2.2 8.2 11.1 4.5 2.9 10.0 2.9 5.4 4.1 3.6 10.9 4.2 7.2 4.9 5.5 10.5 0.4 8.0 3.0 10.9 8.5 4.6 7.3 2.9 5.4 7.0 11.5 9.7 4.9 9.7 8.9 13.7 10.3 16.2 12.9 3.6 8.7 3.3 2.3 1.6 7.3 2.4 5.7 14.6 6.8 10.0 4.6 9.5 5.7 0.4 1.6 5.7 4.1 0.9 4.4 4.4 5.0 3.7 0.5 5.8 5.0 3.3 3.2 4.1 0.4 0.9 5.2 2.0 7.8 6.7 3.4 12.1 12.4 3.6 4.9 1.7 4.5 0.1 2.9 5.6 3.9 9.6 12.8 53.2 12.6 8.0 26.6 16.4 44.3 9.4 20.3 18.9 2.3 7.2 9.3 14.7 6.2 3.7 4.2 0.9 11.7 4.0 3.1 7.2 4.2 4.7 3.0 4.4 176.8 11.6 1.5 3.2 15.8 12.1 1.3 4.6 5.0 5.6 33.6 21.9 214.1 2.8 14.2 7.8 1.7 6.9 1.5 4.9 12.4 83.4 3.2 18.5 7.2 137.7 343.3 9.5 1.4 2.6 8.7 17.9 0.3 9.3 2.2 9.9 6.6 1.9 3.2 12.6 27.9 15.7 2.0 2.1 10.8 2.3 1.3 17.7 DTWD1 "MDS009, MGC111207" ENSG00000104047 "DTW domain containing 1" Q8N5C7 15 49621037-49656232 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042214 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Vesicles" Yes No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Vesicles" "HPA042214: AB_2677903" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (3.00e-1)" "unprognostic (3.70e-4)" "unprognostic (8.12e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-1)" "unprognostic (9.87e-2)" "unprognostic (4.44e-3)" "unprognostic (4.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (1.02e-1)" "unprognostic (7.85e-2)" "unprognostic (2.80e-2)" "unprognostic (2.35e-1)" 19.6 11.8 7.7 13.0 10.1 5.4 18.2 8.2 9.1 27.4 6.5 21.1 7.4 22.6 16.8 13.3 21.1 23.0 11.0 9.0 8.9 11.0 11.5 10.9 12.9 5.7 6.9 22.7 33.3 11.5 9.2 12.8 6.0 15.7 11.9 8.8 21.5 14.7 10.3 12.2 9.1 20.5 6.4 9.0 14.9 9.5 9.9 11.7 17.6 21.1 10.0 20.4 15.9 9.8 10.0 11.9 21.2 11.5 41.3 84.1 16.6 29.3 28.6 36.8 27.5 4.2 8.3 16.7 20.3 38.7 16.8 17.8 15.6 15.8 37.7 10.8 11.2 13.8 23.5 14.5 29.1 18.0 11.1 38.8 20.4 24.3 29.7 32.9 15.5 19.3 26.3 17.3 41.7 23.3 12.3 15.1 12.4 22.6 15.7 17.4 44.7 64.9 12.3 7.1 18.6 14.4 34.7 11.5 27.3 22.1 12.1 25.4 10.7 43.6 17.3 25.6 32.3 13.2 22.2 10.0 37.5 53.9 28.3 8.7 9.7 5.2 6.8 11.7 9.8 9.7 10.3 11.6 12.8 10.1 12.0 11.5 2.6 13.9 15.3 25.3 8.9 6.0 7.7 10.1 8.2 9.1 9.0 8.9 5.7 6.9 6.0 6.4 9.9 9.8 39.9 19.2 15.0 36.6 16.6 19.2 15.4 31.9 18.2 41.8 23.0 34.0 18.8 12.8 22.1 35.0 31.3 23.4 27.1 4.7 31.3 20.1 21.0 27.8 88.1 23.6 15.5 20.8 57.2 21.0 27.7 49.9 20.4 14.1 7.0 29.3 25.4 14.9 19.5 18.5 55.2 19.2 40.7 16.4 14.9 11.2 37.9 16.7 16.0 18.7 10.4 20.3 18.6 33.7 66.1 20.8 10.3 28.2 27.0 21.5 9.5 22.0 37.9 40.0 6.6 35.5 46.7 51.2 44.3 19.6 19.0 9.7 16.2 35.4 17.1 12.7 DTX2 "KIAA1528, RNF58" ENSG00000091073 "Deltex E3 ubiquitin ligase 2" Q86UW9 7 76461676-76505995 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 54.0" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 67.7;CAPAN-2: 110.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042931 Approved Supported "Nucleoplasm,Nuclear membrane" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nuclear membrane" "HPA042931: AB_2678227" "unprognostic (1.72e-1)" "unprognostic (1.73e-1)" "unprognostic (1.62e-2)" "unprognostic (1.58e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (2.85e-2)" "unprognostic (1.28e-3)" "unprognostic (7.54e-2)" "unprognostic (4.76e-2)" "unprognostic (2.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (1.13e-8)" "unprognostic (2.87e-2)" "unprognostic (1.53e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-2)" 10.0 5.0 5.6 12.3 6.3 5.1 10.3 3.3 10.1 17.4 13.8 15.8 10.2 9.3 1.1 54.0 10.5 9.3 6.8 4.3 5.9 5.4 8.7 10.3 10.9 11.1 8.1 8.1 10.5 8.4 6.7 5.3 8.1 13.7 8.1 4.4 30.4 3.9 12.5 31.0 13.3 4.3 3.8 13.3 14.2 28.1 13.5 9.0 7.9 2.7 10.1 12.1 27.2 12.8 31.8 67.7 9.9 14.7 5.5 5.4 21.2 6.8 5.7 7.2 9.9 19.1 110.9 9.8 4.7 6.8 38.1 23.2 5.3 32.1 4.5 22.1 11.3 5.6 14.4 16.9 7.4 8.2 13.7 9.6 19.1 18.7 10.0 5.6 5.5 17.2 17.3 14.3 8.8 15.3 12.6 28.6 14.4 23.8 10.2 13.8 9.1 17.7 3.4 24.4 3.9 8.2 10.9 18.4 9.3 8.6 18.5 21.6 5.8 40.5 19.0 13.8 27.1 10.7 13.7 11.2 8.8 8.8 21.3 17.7 11.6 17.2 8.6 13.3 6.2 6.6 7.1 8.5 10.1 7.3 7.1 7.9 22.8 4.2 18.8 17.8 11.0 8.4 5.6 6.3 3.3 10.1 4.3 5.9 11.1 8.1 8.1 3.8 13.5 12.8 7.3 6.4 5.0 5.2 13.1 33.9 19.5 87.2 23.3 2.6 7.1 4.8 2.3 4.3 59.2 7.3 8.4 18.5 12.0 39.1 3.9 19.4 33.0 8.1 3.1 5.9 9.1 3.8 5.7 10.8 13.5 6.5 61.2 10.7 3.8 3.2 7.1 4.3 21.6 3.3 5.2 25.6 22.4 11.0 7.7 10.4 5.6 14.5 7.2 19.7 10.0 5.7 8.2 18.1 10.0 23.1 37.9 4.9 13.9 20.0 21.0 3.2 62.8 9.2 6.6 3.0 7.3 11.0 11.0 27.0 35.4 37.6 9.7 1.9 26.1 62.5 DTX4 "KIAA0937, RNF155" ENSG00000110042 "Deltex E3 ubiquitin ligase 4" Q9Y2E6 11 59171430-59208588 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 33.6;Oligodendrocytes: 33.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 63.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 62.8;CACO-2: 34.5;CAPAN-2: 37.7;OE19: 35.4;RT4: 95.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056760, HPA059294" Approved Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA056760: AB_2683228, HPA059294: AB_2683969" "unprognostic (3.23e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (4.97e-2)" "unprognostic (5.03e-1)" "unprognostic (2.92e-1)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (3.04e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (5.51e-2)" "unprognostic (2.51e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.57e-3)" 10.4 1.9 13.9 5.5 21.2 9.3 9.5 21.4 20.0 8.0 8.2 17.5 16.4 3.8 1.9 4.7 5.8 4.9 3.2 13.2 21.2 8.5 32.5 18.1 5.3 30.2 22.4 15.0 7.9 1.0 4.1 14.8 27.0 7.5 17.2 10.4 21.7 3.1 1.4 3.9 14.4 2.5 33.5 6.7 11.6 1.7 25.6 1.5 10.2 1.7 6.5 15.0 3.9 50.5 4.8 5.7 30.5 0.6 8.5 0.5 62.8 0.4 2.7 0.3 0.4 34.5 37.7 11.6 2.1 0.7 1.2 16.5 9.5 11.8 0.1 0.8 0.5 0.1 6.6 11.2 2.4 0.9 2.3 1.4 19.3 0.1 0.5 2.1 0.0 2.1 0.1 1.1 1.4 2.7 0.5 0.1 16.1 35.4 1.5 4.1 27.1 1.3 2.6 95.2 0.0 0.1 24.3 6.4 0.8 7.7 4.9 0.5 0.3 0.1 4.9 0.1 0.0 0.4 0.1 1.1 0.2 2.8 2.6 0.7 0.4 0.4 0.0 0.4 0.0 1.0 0.0 0.0 0.6 1.3 0.0 0.0 1.5 0.0 0.2 2.8 0.0 0.1 13.9 21.2 21.4 20.0 13.2 21.2 30.2 22.4 27.0 33.5 25.6 50.5 8.9 19.2 16.8 9.4 3.1 1.7 3.2 7.9 2.2 2.0 2.9 3.9 1.4 28.6 21.8 7.3 0.0 15.0 6.9 33.6 0.0 10.2 0.4 1.5 8.1 3.6 4.9 0.0 12.0 4.9 19.2 7.2 12.2 3.0 1.3 4.9 5.7 23.1 3.7 0.0 8.4 10.5 2.0 2.5 2.5 0.4 4.1 2.7 5.4 3.7 0.9 30.3 0.0 7.5 33.9 10.8 16.3 3.4 0.0 3.1 19.8 9.1 14.9 2.0 0.0 22.1 3.6 0.4 1.7 1.8 1.3 5.5 1.2 5.9 18.5 22.5 DUOX1 "LNOX1, NOXEF1, THOX1" ENSG00000137857 "Dual oxidase 1" Q9NRD9 15 45129933-45165576 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 108.5;skin 1: 81.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 83.3;Alveolar cells type 2: 168.6;Endometrial ciliated cells: 67.1;Glandular and luminal cells: 88.5;Respiratory ciliated cells: 64.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.4" "Group enriched" "Detected in many" 6 "cerebellum: 12.4;white matter: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 64.4;hTCEpi: 30.5;RT4: 36.3" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "cerebellum: 9.6" HPA023544 Approved NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA023544: AB_1847878" "unprognostic (2.85e-2)" "prognostic favorable (4.31e-6)" "unprognostic (2.49e-2)" "unprognostic (8.84e-3)" "unprognostic (1.44e-2)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (2.57e-2)" "unprognostic (5.87e-2)" "unprognostic (6.02e-3)" "unprognostic (5.13e-2)" "unprognostic (1.19e-1)" "unprognostic (8.91e-3)" "unprognostic (2.23e-1)" "unprognostic (3.06e-2)" "unprognostic (1.14e-2)" "unprognostic (3.03e-1)" 1.5 14.1 0.7 1.0 1.0 0.2 4.5 12.4 1.2 44.5 0.0 1.0 0.6 3.0 50.0 108.5 14.0 3.3 3.3 1.0 0.3 0.7 0.4 70.1 0.3 0.3 0.3 1.8 0.5 5.2 1.3 1.5 0.6 13.8 0.3 0.6 18.7 13.0 0.4 81.7 0.7 0.4 0.1 0.3 64.3 1.6 0.4 1.1 70.4 0.0 14.7 11.1 42.0 3.2 8.3 0.1 0.5 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 64.4 0.0 6.1 0.0 0.8 0.4 0.0 0.9 0.1 0.0 0.0 0.3 0.0 30.5 0.0 1.9 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.2 0.1 0.0 0.0 36.3 0.8 1.5 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 1.0 12.4 1.2 1.0 0.3 0.3 0.3 0.6 0.1 0.4 3.2 0.9 83.3 168.6 4.2 4.5 11.1 14.3 22.8 11.4 21.3 4.7 2.8 2.4 8.6 32.5 3.7 8.4 5.3 7.6 2.5 0.0 3.8 0.7 67.1 9.4 3.8 21.7 2.7 5.1 5.4 0.6 5.1 17.9 88.5 8.2 7.9 7.9 1.5 1.2 6.7 3.9 4.0 16.2 3.1 43.5 0.3 3.4 3.3 16.0 1.0 3.2 3.5 33.0 9.5 10.6 4.7 4.0 3.8 0.1 9.5 6.8 0.5 64.9 4.4 0.0 8.5 4.7 11.5 7.5 36.4 18.0 3.7 4.5 0.4 5.6 30.0 DUS2 "DUS2L, FLJ20399, SMM1" ENSG00000167264 "Dihydrouridine synthase 2" Q9NX74 16 67987746-68079320 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 118.1;Late spermatids: 94.1;Spermatocytes: 53.1;Syncytiotrophoblasts: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042560, HPA043528" Enhanced Enhanced Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA042560: AB_10965170, HPA043528: AB_10959753" "unprognostic (2.21e-1)" "unprognostic (5.06e-2)" "unprognostic (1.91e-1)" "unprognostic (1.23e-2)" "unprognostic (8.12e-2)" "unprognostic (1.63e-2)" "unprognostic (1.23e-2)" "unprognostic (9.84e-2)" "unprognostic (2.36e-1)" "unprognostic (2.34e-1)" "unprognostic (1.53e-1)" "unprognostic (3.18e-1)" "prognostic favorable (3.50e-5)" "unprognostic (1.44e-2)" "unprognostic (8.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.81e-1)" 5.8 6.8 5.2 12.6 5.8 9.6 5.8 6.8 7.5 6.1 4.6 8.6 5.7 5.3 4.9 12.2 5.1 5.5 6.1 5.3 6.1 5.9 9.2 6.8 18.8 6.8 5.8 4.8 4.4 7.5 4.9 9.9 6.6 5.4 8.4 5.3 5.9 5.0 9.6 10.8 10.4 7.9 5.0 15.9 6.4 27.5 6.4 7.6 5.4 8.9 20.2 7.0 7.4 7.8 17.1 25.5 11.0 17.1 8.8 14.8 20.4 16.1 15.6 33.4 23.7 27.5 29.9 39.7 14.3 17.0 9.8 22.8 26.6 28.5 25.5 6.1 16.0 13.4 15.6 20.6 14.9 15.1 18.4 14.5 21.9 27.5 26.8 12.8 21.3 29.9 16.1 6.5 16.0 24.9 16.0 22.5 12.2 16.9 13.5 26.8 12.5 28.3 18.4 11.8 13.0 11.3 31.8 12.3 7.1 14.1 25.1 8.4 11.7 14.8 13.3 12.9 13.6 18.4 24.5 36.6 10.6 19.7 8.8 12.1 29.2 89.9 9.5 25.8 9.2 56.9 6.5 10.3 21.9 48.4 9.4 8.5 27.8 21.3 37.7 8.6 13.5 17.2 5.2 5.8 6.8 7.5 5.3 6.1 6.8 5.8 6.6 5.0 6.4 7.8 2.5 9.6 4.6 6.8 17.1 2.7 2.0 12.8 4.6 3.9 2.4 2.2 2.6 4.3 6.2 7.3 8.4 29.2 6.0 5.7 5.9 10.4 118.1 1.7 3.5 5.3 4.2 3.0 7.2 5.4 17.3 3.8 4.6 2.6 7.0 7.2 9.3 7.9 13.4 15.2 8.0 5.5 6.1 11.9 2.3 94.1 3.7 6.2 3.6 2.8 13.5 4.5 9.2 5.5 7.3 9.5 3.6 7.9 7.7 3.4 4.2 10.8 4.1 2.9 6.6 3.4 4.7 53.1 15.0 5.2 2.6 61.4 4.2 10.0 6.0 2.1 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: AB_2670577" "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavorable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 16.0 13.3 7.9 17.1 7.7 35.2 20.4 13.4 11.2 22.4 7.6 16.0 17.3 21.2 19.3 30.5 39.0 15.9 14.2 8.1 6.9 20.2 17.9 14.3 25.3 6.1 5.7 23.5 11.0 14.7 14.0 20.5 6.1 16.5 17.4 8.3 16.0 14.4 14.3 27.6 15.3 19.6 4.8 19.0 16.3 16.8 6.5 24.8 16.5 17.8 26.1 25.2 22.4 8.3 39.4 16.7 17.6 18.6 31.2 38.7 31.2 28.2 36.7 35.8 36.4 24.2 29.1 50.6 17.7 30.6 32.1 26.7 22.0 56.8 34.3 35.2 22.9 31.2 12.0 37.3 32.7 35.5 28.0 31.6 67.3 32.1 44.1 31.1 40.4 24.2 33.6 28.6 40.2 21.3 34.3 37.6 28.4 36.7 22.7 13.6 47.3 46.0 29.3 32.1 25.9 14.1 26.1 30.6 35.7 21.0 16.4 18.6 23.1 25.4 31.4 29.5 33.7 30.7 26.2 68.1 23.5 35.5 25.3 72.5 42.2 99.5 56.3 39.3 73.5 68.3 65.8 67.4 47.3 65.9 69.4 65.5 65.2 69.8 40.6 35.7 88.6 71.7 7.9 7.7 13.4 11.2 8.1 6.9 6.1 5.7 6.1 4.8 6.5 8.3 26.5 9.6 12.0 7.5 39.5 83.2 55.1 93.0 39.3 11.0 12.9 15.1 8.6 27.1 45.7 12.9 4.2 32.8 34.8 15.5 50.9 29.6 9.1 18.0 15.7 34.6 12.0 21.0 14.9 27.3 42.0 26.5 16.3 13.6 40.7 20.5 52.1 15.3 30.7 5.0 12.7 18.0 36.7 20.2 27.1 7.0 28.9 17.0 23.2 10.3 34.8 9.8 41.2 13.0 13.8 28.2 17.8 25.6 31.8 30.0 22.8 50.4 38.2 16.6 6.6 18.2 23.1 23.8 34.6 42.8 83.0 38.6 39.8 20.7 18.8 60.9 DYNC1LI1 DNCLI1 ENSG00000144635 "Dynein cytoplasmic 1 light intermediate chain 1" Q9Y6G9 3 32525974-32570858 "Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 192.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035013 Approved Supported Centrosome,Cytosol NA NA 23000 "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Centrosome, Cytosol" "HPA035013: AB_10600807" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.78e-2)" "unprognostic (2.25e-2)" "unprognostic (1.55e-1)" "unprognostic (5.38e-2)" "prognostic unfavorable (9.19e-9)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (7.26e-3)" "unprognostic (5.02e-2)" "unprognostic (1.05e-2)" "unprognostic (2.21e-2)" "unprognostic (2.14e-2)" "unprognostic (5.51e-2)" "unprognostic (4.58e-2)" "unprognostic (2.27e-2)" 17.9 11.3 16.3 17.8 17.3 37.4 21.3 23.9 23.2 15.3 12.9 15.6 13.6 18.6 12.4 15.7 16.3 16.1 48.6 17.0 20.7 21.2 18.7 19.2 20.4 19.2 17.0 16.6 17.8 21.4 13.6 13.0 22.7 20.6 15.7 39.7 11.8 13.8 46.6 35.0 15.0 22.4 14.8 19.5 14.3 40.8 18.2 22.7 14.5 35.2 20.6 19.9 14.1 17.5 40.1 42.2 64.5 40.7 36.2 42.4 177.7 60.4 82.8 106.4 86.9 45.2 33.7 49.7 39.9 61.5 50.6 20.1 65.4 47.3 100.8 47.7 45.5 66.2 28.9 40.7 44.4 75.6 36.9 34.5 37.1 75.3 58.4 38.8 69.8 55.9 75.8 44.6 57.9 32.0 58.2 33.7 66.8 38.1 56.1 50.7 34.4 51.8 44.2 36.0 27.6 41.1 42.4 52.1 47.0 51.2 43.7 43.9 52.3 58.2 48.9 51.2 61.6 32.0 87.1 80.7 32.7 64.5 46.6 33.1 29.5 26.6 10.3 35.4 11.0 13.0 11.1 11.7 33.0 13.4 7.8 10.3 62.7 16.4 59.0 18.0 13.7 28.9 16.3 17.3 23.9 23.2 17.0 20.7 19.2 17.0 22.7 14.8 18.2 17.5 48.6 25.6 28.3 20.5 49.4 43.0 30.9 40.7 40.5 48.0 30.9 28.8 95.7 11.5 40.2 14.7 18.8 34.9 53.8 14.2 46.9 50.5 102.6 65.8 54.9 39.3 30.9 48.8 43.6 46.5 36.6 37.6 25.0 66.8 17.1 29.2 23.6 28.8 39.4 65.6 55.0 23.0 26.4 35.9 54.2 39.9 26.1 50.7 28.4 28.1 80.0 37.2 34.0 25.6 33.5 56.1 20.0 28.6 28.7 23.4 18.9 61.9 44.3 81.9 46.0 36.7 44.9 192.0 169.5 23.7 50.2 11.1 40.8 39.9 16.8 15.0 DYNLL1 "DLC1, DLC8, DNCL1, hdlc1, LC8, PIN" ENSG00000088986 "Dynein light chain LC8-type 1" P63167 12 120469850-120498493 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Transcription, Transcription regulation, Transport" "Activator, Motor protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 4098.6;Respiratory ciliated cells: 2679.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA Yes 890000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039954: AB_2676771" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (2.88e-2)" "unprognostic (5.63e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (4.41e-3)" "unprognostic (4.64e-2)" "unprognostic (6.17e-3)" "unprognostic (1.61e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (7.97e-7)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (7.91e-2)" "unprognostic (1.62e-1)" 268.6 261.9 912.5 186.7 967.7 126.8 268.0 895.2 1292.9 354.2 894.7 325.8 162.8 319.4 322.3 719.9 544.2 242.7 257.5 975.4 944.7 352.6 238.4 222.6 241.6 896.1 898.5 247.0 225.1 228.2 309.7 259.2 914.2 225.9 327.4 181.3 245.4 264.6 85.6 626.7 206.3 390.1 935.1 185.2 244.5 360.3 909.7 306.5 176.1 163.9 357.8 389.8 474.4 1001.2 721.6 811.4 779.2 600.8 677.1 713.6 250.8 968.0 451.6 785.6 466.7 770.8 472.3 400.6 510.3 945.1 753.0 629.6 949.3 818.3 781.0 528.3 617.9 390.4 532.9 1062.5 676.2 412.8 620.5 436.2 863.0 584.6 477.5 855.7 831.8 421.5 502.0 446.1 1056.8 960.1 541.4 894.8 642.2 917.7 935.7 543.0 403.0 499.2 1143.1 659.8 535.2 392.0 789.3 677.7 926.6 812.6 673.6 595.3 635.2 592.3 502.1 525.6 852.2 264.0 562.8 404.6 656.8 645.1 776.6 516.6 291.9 384.2 200.6 303.3 155.3 310.4 207.2 211.7 281.8 219.0 132.0 165.7 50.1 282.9 334.8 461.6 373.5 353.0 912.5 967.7 895.2 1292.9 975.4 944.7 896.1 898.5 914.2 935.1 909.7 1001.2 810.1 195.5 101.9 79.3 341.4 922.2 359.1 1275.0 356.8 138.4 800.0 949.4 170.8 303.1 764.6 399.1 83.4 524.6 484.1 689.9 1113.2 691.2 1407.2 1842.5 528.5 541.9 480.8 332.9 111.2 538.9 897.4 538.5 240.5 488.1 316.7 611.9 521.9 499.0 732.1 85.8 62.8 801.6 1121.0 329.4 706.1 4098.6 516.6 466.3 595.9 42.2 701.6 164.0 248.2 47.3 156.4 754.9 798.6 701.8 234.9 304.7 533.4 1125.0 2679.6 193.5 368.1 440.7 1016.3 961.5 721.4 1005.4 1610.1 1006.6 396.6 586.3 498.2 389.6 DYNLRB1 "DNCL2A, DNLC2A, ROBLD1" ENSG00000125971 "Dynein light chain roadblock-type 1" Q9NP97 20 34516414-34540958 "Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 781.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009845 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "CAB009845: AB_2093671" "unprognostic (2.23e-1)" "unprognostic (7.60e-3)" "unprognostic (5.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (6.44e-4)" "unprognostic (9.10e-2)" "unprognostic (3.41e-2)" "unprognostic (7.79e-2)" "unprognostic (1.71e-1)" "unprognostic (2.11e-1)" "unprognostic (7.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.00e-1)" 168.7 208.4 430.4 96.9 440.2 113.7 163.7 416.5 552.8 163.7 400.8 228.4 113.8 193.0 204.9 155.4 198.5 117.1 275.7 448.5 454.1 265.8 122.0 169.4 123.9 444.7 443.3 153.9 115.0 222.9 204.3 154.6 436.7 180.9 128.2 171.7 142.1 170.7 222.8 222.1 156.4 158.7 416.1 143.0 166.7 66.6 422.8 154.3 174.4 224.5 135.1 191.4 158.8 458.8 244.4 317.6 259.4 207.3 307.5 294.9 175.4 264.1 393.5 399.2 340.7 853.3 231.1 135.6 327.4 402.0 385.5 215.3 282.2 391.6 265.9 164.5 198.8 463.2 286.8 679.1 345.7 217.5 249.6 251.4 250.4 320.2 245.7 306.2 282.2 255.8 195.1 249.0 415.5 313.4 314.7 427.4 148.6 284.7 345.2 158.6 359.6 220.2 618.7 160.8 264.2 273.9 382.9 631.9 359.4 249.2 362.5 240.7 251.9 500.8 122.4 351.2 295.8 208.8 310.3 157.3 430.1 186.7 225.0 225.4 112.5 221.2 88.0 123.1 88.8 144.2 145.6 117.2 128.8 127.3 101.4 102.1 111.4 132.4 144.3 161.2 238.7 135.0 430.4 440.2 416.5 552.8 448.5 454.1 444.7 443.3 436.7 416.1 422.8 458.8 188.4 169.9 106.5 26.1 107.9 146.8 176.8 215.9 100.2 105.4 136.0 200.3 125.5 170.1 157.4 292.4 58.4 297.8 112.9 283.9 481.3 264.4 34.0 266.4 139.5 170.9 226.7 98.2 34.7 223.4 211.4 149.1 85.1 208.5 159.0 149.8 162.4 104.1 287.9 80.8 30.0 284.6 256.3 127.8 131.5 51.0 234.9 139.1 193.9 19.7 236.2 435.8 148.3 20.1 61.4 317.5 379.3 240.3 117.0 240.4 388.9 781.8 253.1 127.6 203.8 101.8 210.8 65.6 77.2 106.3 150.0 342.3 124.9 90.9 160.5 184.3 DYRK3 "hYAK3-2, RED, REDK" ENSG00000143479 "Dual specificity tyrosine phosphorylation regulated kinase 3" O43781 1 206635536-206684419 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 48.0" "Cell type enhanced" "Detected in many" "Early spermatids: 235.3;Late spermatids: 48.1;Spermatocytes: 108.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-HME1: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075041 Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA075041: AB_2686730" "unprognostic (6.51e-2)" "unprognostic (1.24e-2)" "unprognostic (3.36e-2)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-4)" "unprognostic (2.69e-1)" "unprognostic (3.91e-1)" "unprognostic (2.71e-1)" "unprognostic (2.79e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (9.41e-7)" "unprognostic (2.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (7.62e-3)" 7.6 2.4 3.7 4.2 3.8 8.8 5.7 1.7 3.7 5.6 5.6 2.3 1.0 5.3 3.1 2.8 5.7 13.5 8.3 5.1 3.8 3.3 4.1 5.5 1.6 3.8 5.1 4.9 3.9 3.0 6.5 1.2 3.4 2.9 1.4 6.4 4.3 3.0 0.8 1.5 1.7 8.1 2.6 1.3 3.1 48.0 3.8 5.9 8.3 1.9 1.8 7.5 2.8 3.5 5.0 6.7 1.6 9.8 16.7 15.9 0.4 15.4 36.7 15.0 19.6 0.4 2.7 7.6 2.2 20.1 25.8 1.5 8.6 14.1 15.8 0.1 4.8 10.5 8.9 1.7 26.9 7.5 6.8 10.9 8.9 25.6 73.6 15.1 11.8 11.6 20.1 1.4 23.2 2.0 16.9 4.4 13.2 0.5 10.8 41.1 4.9 0.1 4.8 0.4 9.3 6.9 13.6 0.6 20.3 2.0 2.0 1.9 8.1 31.1 11.2 14.8 13.2 5.6 2.2 9.1 17.7 8.3 2.9 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.5 0.0 0.0 2.7 0.0 0.0 3.7 3.8 1.7 3.7 5.1 3.8 3.8 5.1 3.4 2.6 3.8 3.5 13.9 3.2 8.2 4.2 1.0 6.5 10.7 9.6 3.4 0.2 4.7 3.3 10.8 1.5 4.2 1.8 10.4 0.0 1.5 0.3 0.0 5.1 235.3 12.6 8.0 8.5 2.4 23.6 3.6 2.2 0.1 12.7 1.1 5.9 0.0 3.4 3.9 1.1 1.0 0.0 1.5 0.4 2.0 1.0 4.6 48.1 4.1 2.9 8.8 1.0 1.0 3.4 0.0 2.5 0.3 1.2 1.2 1.9 2.1 3.8 0.2 1.7 10.5 8.2 6.6 10.2 10.4 108.7 6.4 1.3 3.7 0.4 2.4 3.0 0.6 5.3 E2F7 ENSG00000165891 "E2F transcription factor 7" Q96AV8 12 77021248-77065569 "Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.3" "Cell type enhanced" "Detected in many" "Early spermatids: 46.9;Endometrial ciliated cells: 17.2;Late spermatids: 70.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "midbrain: 5.8;pons: 6.4;thalamus: 11.3" HPA064866 Supported "Nuclear speckles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "HPA064866: AB_2685374" "unprognostic (1.21e-1)" "unprognostic (8.92e-2)" "unprognostic (7.39e-2)" "unprognostic (7.27e-2)" "unprognostic (1.54e-1)" "unprognostic (3.80e-2)" "unprognostic (6.14e-5)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (3.57e-2)" "unprognostic (5.67e-5)" "unprognostic (1.42e-1)" "unprognostic (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.00e-1)" "unprognostic (2.51e-1)" 0.2 0.1 0.2 1.1 0.2 5.0 0.2 0.0 0.3 0.3 0.3 0.9 0.7 0.2 0.0 1.4 0.6 0.7 0.2 0.2 0.2 0.1 0.2 0.3 1.5 0.7 0.8 0.1 0.2 0.1 0.5 1.0 0.4 0.2 1.5 0.2 0.2 0.1 0.0 1.1 0.8 0.3 0.6 0.3 0.6 2.9 0.2 8.3 0.1 0.1 1.6 0.6 0.5 0.2 20.1 9.4 25.7 10.1 0.8 2.5 31.1 27.6 29.8 14.2 17.0 12.8 6.6 11.2 5.4 5.5 29.5 15.1 15.5 29.8 27.1 4.4 10.4 9.8 27.3 7.3 5.9 8.5 8.8 0.8 7.7 37.4 22.9 8.3 14.2 19.0 10.4 8.9 29.5 10.1 31.9 0.1 18.1 6.7 21.9 23.0 22.2 6.2 3.5 16.8 16.3 10.7 22.9 7.9 6.5 10.9 12.6 8.7 39.3 53.5 26.8 23.0 36.7 9.5 5.8 7.1 19.3 3.8 34.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.4 0.0 0.2 0.2 0.0 0.3 0.2 0.2 0.7 0.8 0.4 0.6 0.2 0.2 0.1 0.0 0.5 2.3 0.5 0.3 1.0 1.4 4.6 0.0 0.6 0.9 2.1 0.0 2.2 0.0 0.0 1.8 0.4 1.5 0.0 0.3 46.9 17.2 0.8 1.5 0.0 7.4 0.4 1.1 3.1 0.8 6.1 3.1 4.5 6.3 0.0 0.0 0.9 0.0 0.2 1.2 2.0 0.3 1.2 70.2 0.3 1.3 0.0 3.7 0.0 1.6 0.0 0.5 0.0 12.0 0.1 0.7 6.9 1.7 0.0 0.0 3.1 0.1 0.0 0.0 1.2 1.2 2.1 6.3 0.6 0.3 0.8 0.4 2.1 4.3 E2F8 FLJ23311 ENSG00000129173 "E2F transcription factor 8" A0AVK6 11 19224063-19241620 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.2;lymphoid tissue: 11.8;skeletal muscle: 12.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 34.1;Gastric mucus-secreting cells: 10.2;Plasma cells: 9.7;Squamous epithelial cells: 10.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA064882, HPA076614" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli "Nucleoplasm, Cytosol" "HPA064882: AB_2685381, HPA076614: " "unprognostic (5.62e-2)" "unprognostic (5.24e-2)" "unprognostic (3.17e-2)" "unprognostic (6.99e-3)" "unprognostic (2.86e-2)" "unprognostic (1.66e-2)" "unprognostic (1.29e-5)" "unprognostic (1.94e-2)" "unprognostic (3.90e-3)" "unprognostic (2.41e-1)" "unprognostic (7.29e-4)" "unprognostic (1.16e-2)" "unprognostic (9.13e-8)" "unprognostic (1.02e-3)" "unprognostic (1.37e-1)" "unprognostic (3.81e-1)" "unprognostic (4.28e-3)" 0.3 0.1 0.0 2.8 0.0 14.2 0.5 0.1 0.1 1.0 0.0 4.0 3.8 0.4 0.0 4.9 0.9 0.4 2.1 0.0 0.0 0.1 0.3 0.3 7.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.4 5.1 0.0 0.9 0.2 12.6 3.0 3.0 0.6 0.0 1.3 5.6 1.7 0.0 11.8 0.1 0.4 7.3 1.8 1.3 0.1 23.3 7.2 7.1 9.8 0.4 1.1 31.7 13.0 3.7 15.3 16.4 25.4 7.8 23.5 5.5 4.3 9.0 20.2 17.2 1.6 13.5 15.9 14.9 8.0 4.1 7.1 0.0 12.7 19.2 0.3 0.1 3.1 1.0 0.9 21.0 17.2 17.6 22.1 6.3 11.6 25.8 16.6 6.9 26.3 10.1 26.9 12.8 16.0 6.6 16.8 6.0 7.0 5.5 11.3 1.3 4.0 7.7 13.7 4.2 7.3 9.0 18.3 11.8 7.7 16.2 30.6 9.0 24.4 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 1.1 0.1 1.3 0.0 0.0 0.3 0.1 3.8 0.0 0.5 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.4 3.3 0.8 0.8 1.2 34.1 0.1 0.0 1.7 1.0 10.2 3.3 0.0 3.1 0.0 0.0 2.4 0.0 0.0 3.9 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 1.2 0.0 9.7 0.1 0.4 0.2 5.6 0.0 0.0 1.5 0.9 4.0 3.1 10.0 0.3 0.3 2.2 0.5 6.3 0.9 EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9;brain: 16.9" "Group enriched" "Detected in some" 5 "Adipocytes: 29.6;Endothelial cells: 13.1;Fibroblasts: 14.9;Skeletal myocytes: 33.5;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 12.5;HAP1: 13.6;LHCN-M2: 25.4;NB-4: 35.7;RH-30: 13.2;SCLC-21H: 28.7;THP-1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (2.96e-1)" "unprognostic (3.78e-2)" "unprognostic (8.63e-3)" "unprognostic (2.60e-2)" "unprognostic (7.68e-2)" "unprognostic (4.50e-3)" "unprognostic (8.53e-6)" "unprognostic (2.93e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.63e-1)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (9.49e-2)" "unprognostic (4.58e-2)" 23.9 0.6 0.3 1.0 0.1 0.1 13.7 1.4 0.2 4.1 0.4 2.7 0.2 2.3 0.8 1.4 4.8 2.4 9.4 0.1 2.7 0.5 0.5 0.2 6.9 6.5 8.5 1.0 1.3 2.1 0.9 2.5 3.8 2.4 0.5 1.9 3.0 1.1 7.9 3.3 1.0 1.5 16.9 0.2 1.6 1.6 3.2 1.3 7.3 7.7 1.0 3.3 5.5 1.1 0.0 0.0 0.6 0.1 12.5 10.3 0.1 0.8 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 25.4 0.0 0.0 35.7 0.0 0.0 0.0 0.3 13.2 0.0 0.0 0.1 28.7 0.4 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 1.3 8.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.4 0.2 0.1 2.7 6.5 8.5 3.8 16.9 3.2 1.1 29.6 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 1.8 0.3 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 13.1 0.0 0.0 0.9 0.0 0.0 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.5 0.4 0.3 0.4 0.0 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.7 0.0 33.5 11.7 0.0 3.4 0.1 0.9 0.0 0.2 0.1 0.0 0.1 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 328.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 674.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" 10.2 73.3 16.7 17.1 17.2 48.3 17.4 18.5 17.8 19.4 22.0 50.6 85.5 11.0 17.3 41.3 14.3 10.5 32.5 16.8 18.7 44.0 328.5 24.4 18.8 24.4 16.6 12.7 26.0 44.0 7.2 8.2 24.2 40.6 57.5 10.7 25.0 11.7 9.5 27.8 54.2 14.9 15.8 16.9 31.6 14.2 15.9 28.2 14.4 10.6 32.7 14.1 23.3 16.0 224.5 96.4 107.4 77.0 74.5 39.2 50.5 48.2 43.6 64.3 93.9 169.9 382.7 115.9 35.2 41.3 83.5 230.3 217.5 293.8 49.8 85.8 149.7 50.1 115.2 139.3 57.8 179.2 138.2 51.3 108.6 112.9 86.4 22.5 46.5 98.1 77.6 119.5 50.7 163.7 119.1 199.9 118.2 88.3 199.1 93.8 10.3 363.7 175.6 68.8 110.0 59.6 175.4 122.6 31.2 91.5 122.9 71.1 46.6 33.1 56.2 132.9 63.1 47.5 72.1 107.7 78.7 239.7 40.6 96.1 37.7 97.1 129.4 53.4 104.5 71.5 90.5 116.7 53.5 57.2 76.5 99.7 7.3 63.9 57.2 105.4 103.1 93.6 16.7 17.2 18.5 17.8 16.8 18.7 24.4 16.6 24.2 15.8 15.9 16.0 15.2 32.1 49.8 2.9 38.9 37.1 58.2 245.6 23.3 23.8 57.8 26.2 49.9 77.2 116.6 53.3 8.4 55.9 74.5 140.3 39.2 91.7 10.5 30.5 14.7 26.1 30.0 48.8 7.4 239.1 113.0 21.4 36.2 56.5 40.6 41.2 27.1 674.6 65.0 8.4 10.3 96.8 93.6 30.2 36.0 11.8 13.4 31.9 37.4 4.7 34.8 19.3 101.0 5.0 5.1 156.7 137.3 14.7 54.4 46.4 171.9 99.7 34.8 23.3 13.1 12.5 23.6 8.7 22.7 47.6 45.5 37.5 57.1 128.7 149.1 71.1 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 ECT2 ARHGEF31 ENSG00000114346 "Epithelial cell transforming 2" Q9H8V3 3 172750682-172821474 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Guanine-nucleotide releasing factor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Spermatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA036363, HPA053261" Enhanced Nucleoplasm,Cytosol No Yes "Cluster 1: Neutrophils - Mixed function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA036363: AB_2732472, HPA053261: AB_2682094" "unprognostic (3.83e-2)" "unprognostic (4.34e-1)" "unprognostic (1.27e-2)" "unprognostic (4.22e-3)" "unprognostic (4.49e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (6.82e-6)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.82e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (2.44e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.08e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" 3.6 3.3 2.1 8.2 1.9 19.8 7.5 3.4 3.4 8.1 1.4 11.5 9.3 4.4 1.8 8.9 3.3 5.3 3.2 2.4 1.4 4.3 2.6 5.2 10.5 2.1 1.7 1.3 2.9 3.6 1.2 8.8 2.7 3.2 15.8 12.5 5.6 2.6 2.1 7.1 7.6 7.5 0.7 4.3 9.4 15.9 2.3 23.3 3.9 2.7 11.4 6.9 4.2 3.5 192.0 133.6 103.2 54.0 10.6 21.8 51.6 81.5 67.5 121.4 116.9 74.7 196.9 47.2 122.1 48.8 116.0 81.8 84.2 53.1 164.3 67.8 46.6 29.6 70.0 38.5 4.6 46.2 32.8 7.1 9.0 72.2 73.2 34.0 53.0 68.6 31.3 67.2 97.2 67.6 47.5 34.6 84.4 156.7 72.0 33.7 101.1 60.7 92.2 43.7 68.6 44.1 104.5 117.4 42.2 51.5 195.4 34.1 46.5 58.5 55.7 79.6 174.9 32.8 47.2 88.2 51.6 39.7 78.0 6.0 2.0 0.7 1.0 1.7 1.1 1.4 1.4 0.9 1.6 1.3 0.6 0.9 6.3 0.7 0.7 1.6 2.5 0.7 2.1 1.9 3.4 3.4 2.4 1.4 2.1 1.7 2.7 0.7 2.3 3.5 6.7 6.4 3.2 4.2 3.8 19.5 4.9 6.2 9.1 3.4 10.1 6.5 3.6 5.7 5.7 3.7 64.6 12.0 2.9 10.7 0.0 9.5 3.3 20.1 6.6 7.7 4.8 25.2 6.5 9.2 14.9 6.0 17.9 20.5 0.0 17.9 5.3 2.9 7.3 0.0 2.5 13.5 10.2 4.7 6.3 2.8 0.9 5.1 7.2 15.0 2.8 3.1 2.1 3.0 4.9 20.7 3.8 1.5 9.6 12.8 1.5 3.7 11.0 16.3 0.0 2.9 5.2 42.6 30.4 16.9 12.8 3.8 4.1 3.3 13.5 8.8 EDAR "DL, ED1R, ED3, ED5, EDA1R, EDA3" ENSG00000135960 "Ectodysplasin A receptor" Q9UNE0 2 108894471-108989372 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 3.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.4;Macrophages: 1.1;Squamous epithelial cells: 5.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "naive CD4 T-cell: 7.5;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 75 "T-cells: 7.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.7;HaCaT: 10.2;OE19: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA042292 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA042292: AB_10794648" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (2.22e-2)" "unprognostic (1.24e-2)" "unprognostic (4.68e-2)" "unprognostic (1.21e-2)" "unprognostic (2.30e-1)" "unprognostic (2.53e-2)" "unprognostic (3.70e-1)" "unprognostic (1.31e-1)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (8.83e-7)" "unprognostic (9.21e-2)" "unprognostic (5.61e-2)" "unprognostic (2.29e-1)" "unprognostic (5.03e-3)" 0.0 0.0 0.0 0.9 0.0 0.3 0.2 0.0 0.2 0.6 0.0 1.3 1.1 0.5 0.2 3.6 0.2 0.9 0.0 0.1 0.0 0.6 0.9 0.2 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.7 1.9 0.0 0.6 0.1 0.0 1.4 1.0 0.0 0.0 0.2 0.9 0.1 0.1 1.2 0.0 0.0 1.2 1.5 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.7 0.0 0.4 0.0 0.0 10.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 7.5 3.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.4 0.0 0.1 0.6 0.5 0.0 0.8 0.0 0.0 0.2 0.1 0.1 0.0 0.7 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.8 0.0 0.3 0.8 EEF1G EF1G ENSG00000254772 "Eukaryotic translation elongation factor 1 gamma" P26641 11 62559596-62574086 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1021.0;Plasma cells: 770.5;Squamous epithelial cells: 1166.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040688, HPA055316" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 2500000 "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Cytosol "Golgi apparatus" "HPA040688: AB_10961632, HPA055316: AB_2732593" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (2.44e-1)" "unprognostic (1.37e-2)" "unprognostic (2.28e-1)" "unprognostic (1.60e-1)" "unprognostic (9.22e-4)" "unprognostic (1.14e-1)" "unprognostic (5.14e-2)" "unprognostic (5.07e-3)" "unprognostic (1.86e-1)" "unprognostic (8.59e-2)" "unprognostic (8.99e-2)" "unprognostic (1.00e-1)" "unprognostic (1.08e-1)" "unprognostic (1.16e-1)" "unprognostic (6.04e-2)" 1237.6 883.6 646.7 951.1 663.7 1897.3 1890.9 640.9 722.0 1595.1 659.8 1229.0 1094.9 1078.6 1079.3 1634.9 1555.9 749.8 1089.3 616.4 690.9 1162.4 885.3 818.1 1532.7 678.1 661.0 2604.5 2191.5 835.7 708.1 780.5 675.9 1219.1 1272.4 416.0 1588.0 875.6 4810.2 2215.7 1098.5 991.5 690.1 1073.0 1090.2 441.9 677.4 1281.7 1050.2 3030.5 1951.7 1173.7 1440.6 676.7 1773.6 1824.3 1859.1 2656.2 2742.6 3529.1 1866.2 1505.0 2692.9 1830.1 1392.3 2045.9 2161.9 5161.2 2365.4 2392.2 1048.0 2018.3 2229.8 2200.1 1663.3 1693.2 2071.2 1348.7 2061.8 2120.7 2974.2 2810.2 1523.6 4060.8 3913.9 1812.1 4419.8 3014.9 2562.7 1777.2 2755.8 2451.2 2190.6 3611.0 3035.5 4895.3 2304.9 1546.3 1575.0 2545.1 2390.9 4978.7 2454.9 2276.4 1608.2 2002.3 901.7 3010.3 4214.5 1179.1 3496.3 3012.0 1759.8 1057.1 1476.4 2070.0 1338.6 1680.0 1783.1 2609.2 1210.8 2005.2 1517.1 883.9 2365.5 589.6 2182.3 2151.6 4333.1 5399.6 4153.2 2825.0 3623.0 5080.7 6117.7 4188.5 320.6 3285.2 1837.0 2869.7 3307.5 11090.3 646.7 663.7 640.9 722.0 616.4 690.9 678.1 661.0 675.9 690.1 677.4 676.7 2.8 150.6 366.9 14.4 403.6 7.9 2.5 8.8 1021.0 0.5 21.9 10.3 0.0 14.3 300.8 1.8 2.1 17.7 9.6 63.7 3.9 124.8 4.3 2.2 7.2 70.2 148.5 405.0 8.4 188.5 26.8 149.5 252.8 3.5 375.6 1.8 11.0 4.9 12.5 0.0 13.8 152.0 4.1 8.8 4.9 18.8 3.1 134.7 1.8 24.4 126.4 0.8 16.5 6.0 13.0 114.9 121.0 2.2 770.5 3.0 132.1 12.1 152.0 0.5 0.0 1.6 43.9 1.4 0.8 1166.7 6.1 21.1 235.3 1.1 223.8 2.3 EEF2K "CaMKIII, eEF-2K" ENSG00000103319 "Eukaryotic elongation factor 2 kinase" O00418 16 22206278-22288738 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 49.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 69.1;Late spermatids: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.5;HL-60: 1.6;HMC-1: 1.8;NB-4: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007818, HPA056061" Approved Approved Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "CAB007818: AB_598150, HPA056061: AB_2683021" "unprognostic (4.79e-2)" "unprognostic (6.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-1)" "unprognostic (1.94e-2)" "unprognostic (5.09e-3)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.74e-1)" "unprognostic (8.50e-2)" "unprognostic (2.01e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (2.38e-4)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" 19.8 7.1 1.0 0.4 0.9 0.7 15.9 1.5 2.2 17.2 0.7 20.1 0.3 14.3 0.7 9.1 13.1 0.3 9.2 0.9 1.2 3.6 7.8 9.0 0.5 1.1 0.9 8.2 12.9 0.0 5.2 0.4 1.2 19.6 0.2 0.3 15.0 0.2 24.9 49.0 8.1 0.3 0.9 8.0 9.8 2.3 1.4 0.0 6.3 0.0 0.2 18.8 15.4 1.1 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 1.5 0.2 0.0 0.0 0.1 0.0 0.6 0.2 1.0 0.0 1.6 1.8 0.0 0.4 0.1 0.1 0.3 0.1 0.1 0.2 1.3 0.0 0.0 0.1 1.6 0.1 0.4 0.0 0.4 1.0 0.2 0.4 0.0 0.3 0.6 0.0 0.0 0.2 0.1 0.2 0.5 0.5 0.7 0.3 1.4 0.0 0.3 0.1 0.3 1.0 1.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.4 0.1 0.0 1.0 0.9 1.5 2.2 0.9 1.2 1.1 0.9 1.2 0.9 1.4 1.1 43.7 22.4 13.3 22.5 7.3 12.6 9.6 3.9 31.3 69.1 15.4 9.3 17.3 12.8 9.8 9.2 14.6 16.3 12.7 24.2 0.0 4.9 42.9 42.4 12.6 18.4 3.0 7.6 21.2 13.4 11.7 19.2 26.0 34.9 29.2 12.0 22.5 17.7 18.7 1.7 37.4 12.3 4.1 15.3 16.2 76.6 14.3 8.7 8.8 15.9 7.9 6.1 6.2 31.7 8.6 10.2 26.3 15.8 19.6 6.6 12.5 4.0 14.9 21.6 6.6 43.5 10.0 1.3 4.2 16.9 23.0 7.8 7.8 5.7 8.1 6.7 EFNA3 "Ehk1-L, EPLG3, LERK3" ENSG00000143590 "Ephrin A3" P52797 1 155078837-155087538 "Predicted membrane proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 30.9;skin 1: 102.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 63.2;Basal squamous epithelial cells: 44.3;Extravillous trophoblasts: 30.0;Squamous epithelial cells: 32.6;Suprabasal keratinocytes: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 46.3;SCLC-21H: 26.8;T-47d: 25.3" "Low region specificity" "Detected in all" CAB010494 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "CAB010494: AB_2097783" "unprognostic (3.75e-2)" "unprognostic (1.53e-2)" "unprognostic (1.56e-2)" "unprognostic (1.51e-2)" "unprognostic (3.88e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.86e-2)" "unprognostic (3.56e-1)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.66e-10)" "unprognostic (2.83e-3)" "unprognostic (6.38e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-3)" 1.3 2.1 14.0 0.7 15.1 0.2 5.2 7.4 23.3 13.1 5.0 3.5 1.0 1.3 3.8 30.9 0.8 0.6 1.0 17.9 12.3 1.6 3.4 0.7 0.6 13.9 10.6 1.6 1.1 5.6 14.5 0.8 13.3 2.3 3.6 3.2 5.5 0.5 0.8 102.4 1.5 0.7 8.7 1.2 1.1 3.6 12.5 1.1 1.0 0.6 2.4 0.9 28.0 15.4 6.1 1.5 2.6 16.6 2.9 1.5 1.9 0.3 0.5 0.7 1.0 1.0 2.6 4.7 2.7 0.6 1.5 10.0 18.4 3.7 0.6 2.8 4.0 0.6 0.6 1.3 0.3 0.7 3.3 0.8 4.5 0.3 1.1 7.7 1.4 3.0 3.0 2.9 0.6 8.3 0.9 2.5 1.8 46.3 4.8 6.0 1.5 15.6 2.0 0.2 26.8 8.2 1.0 17.7 0.5 2.3 25.3 0.9 0.5 1.8 5.1 0.8 0.5 5.6 2.6 1.1 3.1 2.4 0.2 0.0 0.6 0.8 0.8 0.8 0.8 1.0 0.6 0.4 1.4 1.2 0.9 0.5 0.0 2.7 0.3 1.1 1.6 0.4 14.0 15.1 7.4 23.3 17.9 12.3 13.9 10.6 13.3 8.7 12.5 15.4 3.8 0.0 0.6 2.0 2.1 63.2 3.8 13.6 44.3 1.5 16.9 12.2 0.2 0.0 4.4 0.0 0.0 1.1 3.5 8.6 1.9 3.9 0.6 1.6 0.7 4.2 1.2 0.0 6.5 2.9 30.0 1.5 0.0 1.6 0.0 1.6 1.1 1.1 2.1 3.3 7.9 9.1 2.0 1.2 6.8 1.1 1.2 1.3 8.8 1.0 0.8 9.6 3.1 0.0 1.3 3.2 7.4 0.4 0.4 9.9 6.1 1.3 1.1 1.3 0.0 1.1 8.8 6.5 9.3 32.6 108.8 2.9 2.2 10.1 7.4 3.8 EGF ENSG00000138798 "Epidermal growth factor" P01133 4 109912883-110013766 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 110.2;pancreas: 89.5;skeletal muscle: 29.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 12.9;Breast myoepithelial cells: 8.1;Cardiomyocytes: 8.2;Distal tubular cells: 7.9;Excitatory neurons: 8.5;Inhibitory neurons: 11.2;Muller glia cells: 26.2;Skeletal myocytes: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.4;SK-BR-3: 11.6;U-251 MG: 3.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 209000 680000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (2.83e-2)" "unprognostic (1.02e-2)" "unprognostic (8.50e-3)" "unprognostic (1.88e-3)" "unprognostic (4.24e-2)" "unprognostic (1.64e-3)" "unprognostic (5.06e-4)" "unprognostic (8.30e-2)" "unprognostic (2.21e-3)" "unprognostic (4.25e-2)" "unprognostic (1.80e-2)" "unprognostic (2.95e-1)" "unprognostic (7.72e-3)" "unprognostic (4.64e-5)" "unprognostic (2.63e-1)" "unprognostic (9.80e-5)" "unprognostic (3.92e-3)" 0.0 0.0 1.0 0.1 1.0 0.2 14.7 0.2 0.8 0.0 0.2 0.8 0.0 0.4 2.4 0.7 0.3 1.0 2.8 0.9 2.0 110.2 0.0 0.5 0.0 1.4 0.9 0.0 89.5 0.2 0.4 0.0 1.5 1.4 1.1 13.6 15.7 0.4 29.6 0.7 0.2 0.5 1.2 0.1 0.0 0.1 0.7 0.0 3.0 17.4 0.0 0.4 0.1 1.8 0.2 0.2 1.9 0.0 0.0 0.1 0.0 0.4 1.1 0.5 0.4 0.1 0.0 0.0 6.4 0.6 1.6 0.0 0.3 0.0 0.4 0.0 0.3 0.1 0.6 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 1.3 0.1 0.6 0.1 0.0 0.0 2.3 0.0 0.4 0.1 0.1 0.5 0.4 0.2 0.0 0.0 0.0 11.6 0.4 1.2 2.8 0.0 0.0 0.9 1.3 0.0 3.6 0.0 0.0 0.0 1.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.0 1.0 0.2 0.8 0.9 2.0 1.4 0.9 1.5 1.2 0.7 1.8 0.1 0.0 0.0 3.3 0.0 1.0 0.2 0.1 0.0 1.0 12.9 8.1 8.2 0.0 0.5 0.0 0.0 0.0 0.2 2.0 7.9 0.2 5.6 0.2 0.1 0.6 0.0 0.0 8.5 5.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.7 11.2 0.1 0.0 0.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 26.2 0.0 1.5 0.3 1.0 0.4 0.0 0.0 1.1 0.1 1.2 1.0 1.2 0.0 8.2 0.2 0.5 0.4 0.0 1.4 0.0 0.1 0.1 1.6 0.3 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 EGLN2 "HIFPH1, PHD1" ENSG00000269858 "Egl-9 family hypoxia inducible factor 2" Q96KS0 19 40798996-40808434 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 269.1;Late spermatids: 740.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056649 Supported Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA056649: AB_2683203" "unprognostic (1.11e-2)" "prognostic favorable (2.88e-4)" "unprognostic (9.40e-3)" "unprognostic (6.01e-2)" "unprognostic (6.03e-2)" "unprognostic (6.47e-3)" "unprognostic (1.51e-2)" "unprognostic (4.74e-2)" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.81e-4)" "unprognostic (7.10e-2)" "unprognostic (7.48e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (9.99e-2)" "unprognostic (1.38e-3)" 57.6 58.5 99.3 50.0 99.8 52.1 47.6 95.1 140.9 70.0 79.6 65.4 34.3 53.9 31.5 40.2 45.5 39.1 67.8 103.4 96.2 54.2 57.7 74.3 62.4 97.3 99.3 59.0 36.6 27.7 44.5 48.3 97.7 59.9 28.5 16.6 39.2 45.1 40.0 27.4 46.7 40.9 90.5 116.8 47.6 232.1 99.9 41.9 55.8 40.8 44.1 57.9 57.9 98.1 46.5 123.4 55.9 54.4 71.1 51.5 36.5 49.4 41.1 68.9 75.4 102.8 45.7 41.1 41.1 59.3 62.5 29.3 70.8 56.3 36.4 51.7 40.5 54.8 76.4 39.4 76.1 42.7 71.6 63.9 58.5 65.8 37.4 43.3 86.0 44.3 79.3 37.3 73.4 32.9 78.9 70.2 48.7 72.4 42.6 72.7 27.7 27.8 74.0 70.2 51.4 46.9 80.9 62.9 67.2 47.2 83.4 114.0 80.5 85.9 61.7 35.7 59.5 18.7 29.6 75.6 63.0 61.4 65.5 93.2 72.5 190.5 85.8 83.4 91.1 85.2 101.7 90.3 62.6 90.0 105.2 89.6 261.6 61.4 82.3 45.5 100.2 110.5 99.3 99.8 95.1 140.9 103.4 96.2 97.3 99.3 97.7 90.5 99.9 98.1 2.8 22.4 16.8 0.0 43.9 48.8 55.2 33.8 17.6 40.5 3.3 0.8 22.2 31.5 30.7 3.7 14.6 58.1 19.0 83.0 0.0 15.8 269.1 0.9 1.5 49.9 44.9 30.7 0.0 10.1 26.5 27.6 23.9 1.2 17.2 0.8 72.8 33.7 66.7 21.9 0.0 33.9 48.8 39.8 62.4 740.8 63.0 26.3 40.9 0.0 38.5 24.4 60.8 0.0 0.0 14.0 71.0 52.3 8.7 67.6 54.9 1.4 23.0 17.8 39.5 14.6 17.2 159.4 52.5 14.2 38.4 132.6 33.2 2.1 43.7 69.8 EGLN3 "HIFPH3, PHD3" ENSG00000129521 "Egl-9 family hypoxia inducible factor 3" Q9H6Z9 14 33924227-34462774 "Enzymes, Predicted intracellular proteins" "Apoptosis, DNA damage" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 110.3;skin 1: 118.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 213.7;Cardiomyocytes: 105.8;Distal enterocytes: 135.5;Extravillous trophoblasts: 115.9;Suprabasal keratinocytes: 231.6" "Cancer enhanced" "Detected in all" "renal cancer: 50.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 25.5" "Lineage enriched" "Detected in many" 14 "dendritic cells: 25.5" "Cell line enhanced" "Detected in many" "RH-30: 44.6;RPTEC TERT1: 38.2;RT4: 122.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064895 Supported Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "HPA064895: AB_2685384" "unprognostic (3.58e-2)" "unprognostic (4.76e-3)" "unprognostic (1.75e-1)" "unprognostic (8.87e-2)" "unprognostic (6.88e-2)" "unprognostic (1.38e-2)" "prognostic unfavorable (2.14e-5)" "unprognostic (1.39e-3)" "unprognostic (3.44e-2)" "unprognostic (1.79e-1)" "unprognostic (2.93e-2)" "unprognostic (2.90e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.37e-1)" "unprognostic (5.21e-2)" "unprognostic (4.71e-2)" "unprognostic (6.30e-2)" 14.6 0.8 32.9 9.4 40.9 0.3 10.0 38.2 37.5 12.3 15.4 25.9 35.7 10.0 4.4 27.0 9.4 13.8 110.3 29.7 38.9 16.3 4.9 8.3 5.7 34.3 37.5 2.1 4.3 0.3 3.4 25.4 32.2 9.1 20.0 15.2 11.2 12.0 20.8 118.2 40.9 11.7 31.9 4.9 37.7 1.1 42.9 4.9 2.8 6.4 9.8 51.3 20.8 36.1 31.1 8.0 0.9 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 8.2 0.0 10.0 0.1 0.9 0.9 15.0 29.4 0.0 3.1 8.0 8.3 20.5 1.0 0.0 0.0 0.4 4.0 14.5 0.0 0.1 0.0 0.0 2.3 16.9 0.0 0.4 2.7 0.7 0.1 24.3 26.7 2.8 0.0 44.6 11.1 38.2 122.9 6.2 7.0 2.0 11.8 3.2 18.2 12.0 0.1 0.0 0.2 3.2 0.0 1.8 0.4 6.7 0.1 7.2 0.0 0.5 0.0 0.0 1.8 0.1 0.0 0.0 0.0 1.2 0.9 2.6 0.0 0.1 0.1 0.1 1.1 0.0 25.5 0.0 0.9 32.9 40.9 38.2 37.5 29.7 38.9 34.3 37.5 32.2 31.9 42.9 36.1 6.0 0.0 0.6 36.2 1.6 213.7 49.0 56.6 3.4 11.6 16.0 17.0 105.8 4.3 24.8 9.2 2.1 11.4 16.0 135.5 9.8 15.6 1.8 42.3 8.5 25.1 16.2 0.4 1.0 6.9 115.9 16.8 74.9 17.2 1.3 0.1 12.5 0.3 3.1 1.7 4.3 31.6 12.2 1.9 62.8 4.9 2.5 10.8 40.9 0.0 0.9 11.6 0.0 6.6 54.2 46.6 41.9 0.7 0.4 17.4 59.7 20.5 37.2 2.4 0.0 17.7 9.4 1.7 0.3 4.1 231.6 103.0 4.5 1.2 14.1 25.7 EIF4A3 "DDX48, EIF4AIII, Fal1, KIAA0111" ENSG00000141543 "Eukaryotic translation initiation factor 4A3" P38919 17 80134369-80147151 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, rRNA processing, Translation regulation, Transport" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021878 Supported Supported Nucleoplasm NA NA 280000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA021878: AB_1848090" "unprognostic (7.24e-2)" "unprognostic (7.33e-3)" "prognostic favorable (3.57e-5)" "unprognostic (1.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.68e-5)" "prognostic unfavorable (1.87e-4)" "unprognostic (3.71e-1)" "unprognostic (5.06e-2)" "unprognostic (4.64e-2)" "unprognostic (2.64e-2)" "unprognostic (9.78e-3)" "unprognostic (5.81e-2)" "unprognostic (9.20e-2)" "unprognostic (1.38e-2)" "unprognostic (2.91e-3)" 65.8 81.4 19.0 49.1 21.1 185.8 44.2 21.5 27.2 51.2 22.8 44.3 38.6 46.6 38.8 81.9 54.7 40.1 38.0 22.3 21.0 45.1 42.6 44.0 67.0 19.9 19.5 66.5 37.0 58.5 41.1 52.9 20.3 38.7 47.5 32.3 42.4 32.6 37.3 64.8 38.9 42.6 22.7 47.6 41.4 42.8 20.0 78.2 37.0 34.9 74.7 83.4 55.1 24.7 237.2 208.9 140.5 103.8 105.5 63.2 114.4 119.3 91.0 177.7 141.4 223.7 110.3 221.4 67.9 112.9 126.4 152.2 194.9 136.2 195.0 71.5 192.3 142.5 159.3 244.3 103.1 253.8 133.4 98.7 68.7 149.5 119.4 71.8 147.2 128.7 189.8 140.2 105.3 178.9 224.8 132.8 145.0 223.8 190.0 168.5 282.7 172.2 85.8 196.5 186.1 100.1 170.9 334.2 151.9 130.1 219.3 166.7 100.5 108.7 138.6 159.9 200.3 104.4 86.2 403.2 88.0 158.7 113.3 126.1 167.0 137.4 101.1 174.6 131.2 142.4 128.2 119.4 200.0 119.8 116.9 115.2 98.7 132.9 143.4 326.0 158.2 232.6 19.0 21.1 21.5 27.2 22.3 21.0 19.9 19.5 20.3 22.7 20.0 24.7 117.9 41.7 48.0 6.8 135.1 283.1 273.4 212.9 107.0 23.3 77.0 109.2 61.5 38.6 107.8 29.5 16.7 140.1 165.7 75.4 64.6 85.6 33.2 132.9 109.2 70.5 60.3 24.4 4.1 115.2 225.1 144.3 149.4 248.2 92.6 42.6 32.2 27.0 108.5 6.7 4.3 83.2 89.5 63.4 255.0 12.1 67.1 199.6 103.2 10.3 67.9 48.6 23.7 5.5 7.6 86.6 83.1 49.7 118.6 96.0 47.9 65.0 61.4 32.5 85.5 109.7 207.8 99.4 123.2 77.6 299.1 261.9 138.4 98.0 77.7 252.5 EIF4ENIF1 "2610509L04Rik, 4E-T, Clast4, FLJ21601" ENSG00000184708 "Eukaryotic translation initiation factor 4E nuclear import factor 1" Q9NRA8 22 31436977-31496108 "Plasma proteins, Predicted intracellular proteins" "Protein transport, RNA-mediated gene silencing, Translation regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 54.6;Late spermatids: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001619, HPA002078" Enhanced Enhanced Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA001619: AB_1078727, HPA002078: AB_1078728" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" "unprognostic (3.01e-2)" "unprognostic (1.53e-1)" "unprognostic (6.72e-2)" "unprognostic (2.28e-3)" "unprognostic (1.30e-2)" "unprognostic (4.95e-2)" "unprognostic (9.92e-2)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "prognostic favorable (1.57e-4)" "unprognostic (2.30e-1)" "unprognostic (1.92e-1)" "unprognostic (7.32e-2)" "unprognostic (2.45e-2)" 12.5 11.9 14.3 10.4 14.8 14.3 11.9 19.7 17.3 15.9 11.4 19.4 11.4 15.0 13.0 14.0 13.8 7.8 13.2 15.3 15.0 12.3 8.4 12.1 12.6 13.6 14.7 15.0 10.5 16.7 10.8 13.6 14.3 13.5 11.5 18.0 12.1 13.2 20.2 15.7 11.8 12.1 11.6 12.3 12.3 34.7 13.8 12.9 13.5 14.5 14.9 15.6 14.3 17.3 19.8 11.6 29.4 16.0 16.1 14.2 11.7 13.7 16.8 21.4 19.8 13.4 7.0 25.3 7.9 20.7 14.3 19.1 26.9 12.5 19.7 20.2 27.0 10.3 20.0 15.4 16.7 41.0 17.9 16.6 16.9 15.8 17.8 19.5 18.4 14.8 25.4 27.0 20.3 22.4 27.8 20.3 13.5 18.3 9.5 31.1 24.5 26.0 21.7 14.7 22.6 20.9 18.9 15.4 14.5 19.4 16.4 16.1 20.5 14.3 18.6 14.4 15.5 19.3 20.4 25.1 13.7 14.8 17.1 1.3 2.4 1.2 3.4 3.0 3.5 4.8 1.8 3.3 2.2 2.0 1.8 3.2 2.0 1.0 8.1 4.4 1.4 1.9 14.3 14.8 19.7 17.3 15.3 15.0 13.6 14.7 14.3 11.6 13.8 17.3 8.4 12.8 15.2 23.2 10.6 7.4 7.3 6.2 15.4 18.0 9.6 8.9 22.7 10.0 8.5 12.9 12.5 9.8 13.8 8.6 9.8 8.9 54.6 8.0 12.8 10.2 12.0 12.4 21.0 6.4 5.5 8.1 12.2 13.0 6.3 23.1 11.0 8.9 8.0 18.5 20.5 10.8 8.2 9.5 6.2 98.9 14.6 7.5 7.2 13.1 14.5 8.1 14.4 20.1 20.2 10.2 3.6 15.4 10.3 10.7 5.7 9.4 6.3 13.7 6.6 11.8 11.0 38.7 13.3 10.7 10.5 6.7 8.2 9.0 8.1 8.0 EIF4G1 "EIF4F, EIF4G, p220, PARK18" ENSG00000114867 "Eukaryotic translation initiation factor 4 gamma 1" Q04637 3 184314495-184335358 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding, Translational shunt" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 348.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014774, HPA028487, HPA043866" Approved Enhanced Cytosol NA NA 330000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB014774: , HPA028487: AB_10602219, HPA043866: AB_2678705" "unprognostic (4.14e-3)" "unprognostic (2.10e-2)" "unprognostic (6.01e-2)" "unprognostic (3.01e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (4.27e-3)" "unprognostic (2.35e-1)" "unprognostic (1.54e-1)" "unprognostic (1.55e-3)" "unprognostic (7.06e-3)" "unprognostic (2.42e-1)" "unprognostic (7.15e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-1)" "unprognostic (2.33e-3)" 86.2 91.8 24.8 75.7 22.2 84.0 69.0 17.9 22.2 66.6 34.1 81.8 62.0 71.3 32.7 126.8 59.6 50.9 90.8 23.3 29.8 53.9 113.0 74.2 55.7 38.5 36.1 57.5 96.2 99.3 57.4 59.4 32.4 62.2 56.5 22.3 93.1 59.2 348.3 116.7 67.2 74.7 24.4 58.2 79.9 64.8 37.4 49.1 71.3 177.0 63.2 76.0 85.3 16.6 559.0 232.3 173.1 205.7 196.9 192.5 322.5 298.6 204.1 315.4 238.8 486.5 173.7 348.4 381.9 367.6 358.5 292.7 322.6 365.8 230.5 375.1 345.8 321.3 226.1 206.4 173.4 321.4 212.2 199.6 206.8 292.4 268.8 152.8 278.3 128.8 239.6 267.2 205.7 403.4 219.7 105.3 368.9 241.3 180.8 221.7 183.4 281.9 156.8 331.8 197.7 174.6 258.1 415.6 187.6 144.6 445.2 206.5 364.1 227.2 228.9 297.3 567.9 203.8 263.2 629.0 260.5 271.4 258.3 8.3 16.0 6.7 11.7 14.4 10.8 7.7 7.8 9.6 12.8 9.2 6.9 7.6 5.6 8.7 21.0 18.1 6.0 12.7 24.8 22.2 17.9 22.2 23.3 29.8 38.5 36.1 32.4 24.4 37.4 16.6 63.9 76.9 72.6 23.8 41.7 59.1 78.2 58.0 70.6 24.2 69.3 46.2 109.4 50.1 72.3 62.5 14.6 64.0 37.6 135.5 13.7 98.8 151.6 53.0 67.1 69.3 55.7 82.7 10.8 135.3 74.8 64.5 75.4 85.6 48.0 163.8 43.5 152.8 66.8 21.9 12.9 97.2 50.8 40.8 39.9 202.7 73.0 48.9 33.8 14.0 53.0 23.2 30.9 4.0 10.1 149.0 69.0 56.1 112.9 96.8 77.0 45.4 51.4 23.2 78.9 81.6 78.9 24.8 41.4 120.7 91.8 79.6 46.0 94.8 108.4 95.6 EIF4H "KIAA0038, WBSCR1, WSCR1" ENSG00000106682 "Eukaryotic translation initiation factor 4H" Q15056 7 74174231-74197122 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 990.0;Late spermatids: 2765.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030542 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 750000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Nuclear bodies" "HPA030542: AB_10601368" "unprognostic (2.83e-1)" "unprognostic (9.50e-2)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (3.89e-4)" "prognostic unfavorable (2.15e-4)" "unprognostic (1.61e-2)" "unprognostic (2.72e-3)" "unprognostic (1.79e-1)" "unprognostic (2.99e-2)" "unprognostic (1.72e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-2)" "unprognostic (3.04e-1)" "unprognostic (2.23e-1)" "unprognostic (5.68e-2)" "unprognostic (1.27e-2)" 186.9 174.9 151.0 117.8 159.3 283.3 168.3 163.8 157.3 179.8 129.6 208.4 130.2 186.4 76.6 249.3 163.6 100.0 171.0 149.9 151.9 156.6 197.0 158.4 130.3 161.9 156.9 181.2 226.4 160.7 119.9 162.8 162.2 150.3 100.2 149.8 170.1 125.1 399.8 230.9 148.9 119.2 165.2 137.4 192.9 79.9 164.6 150.2 141.2 173.4 137.2 175.3 179.7 187.1 526.3 341.4 251.3 303.1 220.8 231.8 283.4 359.8 276.3 300.3 289.5 423.3 388.6 444.3 96.6 338.8 424.2 266.6 280.5 481.5 286.3 298.0 329.2 247.5 305.2 345.9 253.1 429.0 236.9 273.2 300.8 326.2 460.7 341.5 326.8 260.1 445.8 186.4 305.2 448.2 342.0 516.8 337.6 430.3 328.9 386.9 342.7 401.5 250.9 324.7 252.7 325.4 340.9 420.3 296.0 331.3 476.8 272.4 340.2 411.6 284.6 345.1 474.4 218.8 299.8 771.4 326.3 435.1 441.4 213.7 229.7 245.6 156.9 255.6 164.5 146.4 161.4 158.3 224.2 132.9 183.9 151.7 150.1 193.5 270.2 95.1 194.7 388.0 151.0 159.3 163.8 157.3 149.9 151.9 161.9 156.9 162.2 165.2 164.6 187.1 105.8 83.3 81.2 15.7 97.1 119.2 153.8 101.5 78.0 93.1 103.0 95.5 43.3 68.6 68.7 44.1 25.0 198.8 91.9 98.7 107.6 148.1 990.0 104.8 98.3 103.0 90.4 79.5 25.3 157.7 381.4 101.6 61.2 112.5 122.4 112.1 79.6 95.7 124.2 97.6 24.6 87.2 91.6 101.2 102.7 2765.8 103.8 86.8 72.9 15.9 157.4 134.7 119.4 16.6 44.2 147.0 82.8 110.6 82.7 140.7 84.6 69.0 57.8 72.3 85.5 107.3 117.7 61.2 64.6 90.1 116.1 395.3 92.4 116.9 109.5 140.4 ELAPOR1 "EIG121, KIAA1324, maba1" ENSG00000116299 "Endosome-lysosome associated apoptosis and autophagy regulator 1" Q6UXG2 1 109113679-109206781 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 156.7;salivary gland: 166.1;stomach 1: 88.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;dendritic cells: 1.2;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 65.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "MCF7: 20.8;SCLC-21H: 16.8;SK-BR-3: 17.6;T-47d: 59.1;U-87 MG: 12.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029869, HPA070749" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA029869: AB_10794320, HPA070749: AB_2686304" "unprognostic (2.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.99e-2)" "prognostic favorable (2.14e-7)" "unprognostic (4.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-3)" "prognostic favorable (5.69e-5)" "unprognostic (2.79e-2)" "prognostic favorable (2.16e-4)" "unprognostic (3.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.22e-16)" "unprognostic (2.46e-1)" "unprognostic (1.75e-1)" "unprognostic (5.64e-2)" "unprognostic (8.02e-2)" 0.8 3.2 3.6 4.1 4.4 0.5 56.7 0.0 4.9 70.1 0.0 28.3 45.5 12.8 9.7 1.6 23.9 5.6 0.2 4.4 13.2 0.1 0.2 5.1 2.5 0.2 0.1 0.1 156.7 9.2 32.9 0.2 0.7 48.6 27.8 0.4 166.1 0.3 0.0 3.9 35.3 1.1 0.0 0.8 88.2 18.3 10.0 0.8 9.0 0.1 1.9 0.4 0.1 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.0 0.5 0.6 0.7 1.3 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 1.0 0.0 0.0 0.5 20.8 0.2 0.3 0.5 0.0 0.1 0.1 0.3 1.1 0.1 0.0 16.8 0.4 0.1 17.6 0.0 0.1 59.1 0.0 0.4 0.0 2.1 0.2 0.2 1.3 3.6 0.0 12.4 0.0 0.1 0.0 0.1 0.0 4.6 0.0 7.6 0.4 7.5 3.2 0.0 0.1 3.3 1.5 65.2 0.5 0.0 0.0 9.8 2.2 3.6 4.4 0.0 4.9 4.4 13.2 0.2 0.1 0.7 0.0 10.0 1.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 ELAVL2 "HEL-N1, HuB" ENSG00000107105 "ELAV like RNA binding protein 2" Q12926 9 23690104-23826337 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 31.8;testis: 43.1" "Cell type enhanced" "Detected in many" "Early spermatids: 62.2;Excitatory neurons: 135.5;Inhibitory neurons: 390.6;Spermatogonia: 159.2" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 25.4;AF22: 37.2;SCLC-21H: 119.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022222, HPA063001" Enhanced Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "CAB022222: , HPA063001: AB_2684918" "unprognostic (3.51e-1)" "unprognostic (4.18e-2)" "unprognostic (2.05e-1)" "unprognostic (1.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-1)" "unprognostic (4.26e-2)" "unprognostic (8.94e-2)" "unprognostic (3.23e-1)" "unprognostic (1.01e-1)" "unprognostic (9.74e-4)" "unprognostic (3.98e-1)" "unprognostic (9.08e-4)" "unprognostic (8.30e-2)" "unprognostic (1.91e-2)" "unprognostic (2.12e-1)" "unprognostic (2.65e-1)" 0.1 1.3 12.4 0.1 15.8 0.5 0.2 1.5 31.8 0.1 0.0 0.4 0.1 0.5 0.5 0.2 0.1 0.2 0.1 10.9 23.2 0.5 0.0 0.2 0.2 15.7 13.0 1.1 0.0 0.1 1.0 0.1 15.3 0.3 0.5 5.0 0.1 0.1 0.1 0.5 0.2 0.2 0.1 0.1 0.1 43.1 15.0 0.0 0.3 0.0 0.1 0.4 0.2 9.4 25.4 0.3 37.2 0.2 0.1 0.3 0.1 0.3 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 7.8 9.9 15.9 0.2 0.0 7.1 0.0 0.1 0.3 0.0 0.2 0.6 0.5 9.6 0.0 11.0 0.0 0.3 0.1 0.9 1.2 5.3 0.0 0.1 0.1 9.8 0.0 11.8 0.1 13.3 0.2 0.0 0.0 119.6 11.5 0.3 0.3 0.3 9.4 0.6 1.9 0.0 0.2 7.9 0.2 0.2 0.1 0.1 0.1 1.3 0.1 1.4 1.1 0.3 0.5 0.1 0.2 0.2 0.3 0.1 0.1 0.1 0.5 0.3 0.4 1.5 0.4 0.2 0.3 0.2 0.0 12.4 15.8 1.5 31.8 10.9 23.2 15.7 13.0 15.3 0.1 15.0 9.4 0.9 0.0 0.0 7.8 0.0 1.0 0.4 0.4 0.6 8.8 0.9 0.6 0.9 0.0 0.1 0.0 0.0 0.0 0.0 1.4 1.9 0.1 62.2 0.5 0.2 1.8 4.2 0.0 135.5 0.0 0.0 0.8 0.0 0.2 0.0 10.6 0.0 0.0 0.1 16.8 390.6 1.2 0.0 0.0 0.7 39.5 3.1 0.2 0.0 7.5 0.0 2.8 0.0 5.5 5.5 0.0 0.2 1.5 0.0 0.4 0.0 0.1 0.0 10.6 0.0 1.4 1.0 13.9 159.2 0.5 0.9 0.0 0.1 0.7 1.3 0.6 ELF5 ENSG00000135374 "E74 like ETS transcription factor 5" Q9UKW6 11 34478791-34525193 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 151.2;salivary gland: 147.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 40.3;Breast glandular cells: 143.2;Breast myoepithelial cells: 57.1;Collecting duct cells: 101.2;Cytotrophoblasts: 26.9" "Cancer enhanced" "Detected in many" "breast cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "RT4: 30.2;T-47d: 56.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062706 Approved Nucleoplasm NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "HPA062706: AB_2684841" "unprognostic (1.13e-1)" "unprognostic (1.48e-1)" "unprognostic (7.55e-2)" "unprognostic (3.31e-2)" "unprognostic (2.41e-4)" "unprognostic (6.90e-2)" "unprognostic (3.93e-1)" "prognostic favorable (3.64e-4)" "unprognostic (1.12e-1)" "unprognostic (3.40e-2)" "unprognostic (8.15e-2)" "unprognostic (3.15e-2)" "unprognostic (1.78e-3)" "unprognostic (3.09e-1)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (2.86e-1)" 0.2 0.0 0.1 0.0 0.1 0.2 151.2 0.2 0.2 0.9 0.4 0.0 2.1 0.0 0.0 1.3 0.1 0.2 0.0 0.1 0.0 17.0 0.2 7.5 0.0 0.0 0.1 0.0 0.5 0.0 0.0 1.4 0.0 2.5 0.0 0.0 147.6 30.4 0.0 6.2 0.0 0.0 0.0 1.1 0.6 0.2 0.1 0.5 0.0 0.0 2.5 5.7 2.3 0.2 0.1 0.0 0.0 0.1 0.0 0.5 3.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 30.2 0.0 0.0 0.0 5.1 0.0 0.1 56.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 1.0 3.2 40.3 0.0 1.1 0.3 1.9 0.9 0.0 0.0 143.2 57.1 0.4 0.0 9.7 101.2 0.0 26.9 1.4 0.0 0.0 0.0 0.2 0.1 0.1 0.8 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 2.0 1.9 0.4 0.1 0.0 0.5 17.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.4 4.8 0.0 0.0 0.2 0.9 2.5 0.2 0.0 0.1 11.5 0.6 0.0 0.0 6.5 ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.7;skin 1: 25.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.2;Gastric mucus-secreting cells: 4.6;Proximal enterocytes: 6.5;Squamous epithelial cells: 21.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 10.5;naive B-cell: 15.9" "Lineage enriched" "Detected in many" 7 "B-cells: 15.9" "Cell line enhanced" "Detected in many" "Daudi: 73.8;OE19: 28.5;T-47d: 39.0;U-698: 149.9" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: AB_10795352, HPA073494: " "unprognostic (2.59e-2)" "unprognostic (4.41e-1)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-3)" "unprognostic (1.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.87e-1)" "unprognostic (3.67e-2)" "unprognostic (8.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-2)" 0.5 0.9 1.0 9.7 1.0 0.2 5.2 1.0 1.1 1.6 4.7 8.0 14.1 0.6 1.1 4.5 3.9 0.7 0.5 1.0 1.1 1.4 0.7 1.5 49.7 1.0 1.1 1.7 0.4 1.6 0.5 3.7 1.1 2.0 12.3 0.1 2.2 1.0 0.4 25.0 12.9 1.0 1.0 1.0 1.8 16.2 1.4 1.5 0.7 1.9 57.7 0.7 0.8 1.1 2.1 0.2 0.6 1.1 4.9 1.2 0.4 0.2 1.3 2.8 3.1 0.0 1.3 73.8 0.1 1.2 0.1 13.7 1.3 0.7 1.4 1.6 7.3 0.4 2.6 4.6 1.0 0.1 0.0 1.4 12.3 0.7 0.2 0.2 1.1 0.4 0.2 0.0 0.7 4.0 1.5 1.4 0.1 28.5 2.4 0.8 0.0 0.0 1.8 0.0 9.5 0.0 1.7 21.5 0.0 0.3 39.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 149.9 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 10.5 0.6 0.1 0.0 15.9 1.1 0.2 0.0 0.1 0.0 2.2 0.6 0.6 1.0 1.0 1.0 1.1 1.0 1.1 1.0 1.1 1.1 1.0 1.4 1.1 0.1 0.0 0.0 0.0 2.2 0.4 0.1 0.2 5.2 0.0 0.7 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.3 1.2 0.0 0.1 1.8 0.4 0.1 0.2 0.0 0.4 0.1 0.7 0.0 0.5 4.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.5 0.0 0.0 0.5 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.1 6.5 0.1 3.1 0.0 0.0 0.2 0.4 0.2 0.2 21.0 1.0 0.3 0.1 0.1 2.3 0.2 ELMO3 "CED-12, CED12, ELMO-3, FLJ13824" ENSG00000102890 "Engulfment and cell motility 3" Q96BJ8 16 67199111-67204029 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Paneth cells: 50.3;Proximal enterocytes: 100.3;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 33.1;CAPAN-2: 49.3;HaCaT: 46.9;T-47d: 45.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021484 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "HPA021484: AB_1848129" "unprognostic (4.49e-3)" "unprognostic (2.04e-1)" "unprognostic (1.10e-2)" "unprognostic (8.08e-2)" "unprognostic (1.39e-1)" "unprognostic (6.16e-3)" "unprognostic (3.14e-1)" "unprognostic (8.17e-3)" "unprognostic (1.73e-1)" "unprognostic (8.06e-2)" "unprognostic (3.40e-2)" "unprognostic (6.95e-3)" "prognostic favorable (2.77e-5)" "unprognostic (3.47e-1)" "unprognostic (2.66e-1)" "unprognostic (1.84e-1)" "unprognostic (1.97e-2)" 2.8 1.8 1.5 4.3 1.4 5.6 8.8 2.4 2.6 6.4 0.3 24.3 33.1 2.0 4.1 25.8 8.5 8.6 1.9 1.1 1.7 21.4 8.1 8.3 2.9 2.1 1.0 1.8 41.0 8.5 29.8 7.1 2.8 19.3 9.1 0.7 20.3 9.6 1.2 33.5 26.3 0.8 0.4 5.6 26.0 13.0 1.3 2.1 19.3 0.3 2.6 8.5 13.2 1.5 22.1 2.5 2.4 3.0 0.4 0.6 33.1 1.3 0.7 1.6 1.4 14.2 49.3 3.0 1.5 0.7 0.7 46.9 2.2 21.6 0.3 1.4 2.9 3.2 4.8 4.7 1.0 1.9 7.5 0.5 15.6 1.2 1.1 1.6 1.7 2.6 3.1 1.5 0.9 18.4 2.0 9.3 3.2 20.7 1.9 4.6 2.3 4.9 2.0 2.9 16.2 3.6 3.2 14.4 1.5 1.3 45.8 3.4 2.8 3.7 4.5 2.3 2.3 4.9 1.7 5.8 1.9 4.4 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 1.5 1.4 2.4 2.6 1.1 1.7 2.1 1.0 2.8 0.4 1.3 1.5 1.8 0.0 13.1 0.0 2.0 8.8 11.9 21.9 13.1 0.9 20.6 16.3 1.2 15.7 12.6 20.2 0.0 33.8 1.0 63.9 17.6 20.1 22.9 8.8 1.7 1.6 13.1 6.9 0.4 24.0 15.0 1.7 47.4 12.2 4.5 1.3 1.4 3.6 3.6 0.0 0.3 33.8 22.4 1.6 3.1 36.3 0.9 2.6 3.6 1.9 2.8 0.4 0.0 0.0 1.0 24.8 50.3 0.7 1.4 7.9 100.3 28.6 12.3 1.5 0.0 0.4 1.6 14.5 5.9 14.4 13.5 16.8 2.3 5.0 52.3 13.0 ELMOD1 DKFZp547C176 ENSG00000110675 "ELMO domain containing 1" Q8N336 11 107591091-107666779 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 32.8;pituitary gland: 21.7;retina: 32.6;skin 1: 28.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 33.5;Excitatory neurons: 126.1;Horizontal cells: 37.0;Inhibitory neurons: 103.9;Oligodendrocyte precursor cells: 80.9" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 14.9;RH-30: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038435, HPA066479" Uncertain Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA038435: AB_10795575, HPA066479: " "unprognostic (2.74e-1)" "unprognostic (1.72e-4)" "unprognostic (2.58e-2)" "unprognostic (9.13e-2)" "unprognostic (3.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.34e-1)" "unprognostic (6.59e-3)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (6.29e-2)" "unprognostic (9.44e-2)" "unprognostic (1.34e-4)" "unprognostic (1.91e-2)" "unprognostic (3.15e-1)" "unprognostic (4.21e-2)" "unprognostic (1.39e-1)" 0.4 2.6 17.2 0.3 27.1 0.1 2.4 13.2 32.8 0.5 0.0 0.5 0.2 0.4 0.1 0.1 2.1 0.1 4.8 24.6 23.5 3.1 0.3 0.4 0.1 15.1 24.8 0.1 0.1 0.9 21.7 0.0 11.8 0.8 0.2 32.6 0.1 0.1 2.6 28.9 0.2 0.3 14.3 0.1 0.1 1.6 18.8 0.4 0.1 1.8 0.0 0.0 0.1 10.7 0.0 0.0 5.6 0.1 0.0 0.1 0.2 0.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.2 4.4 0.5 2.8 0.4 0.5 0.0 2.3 0.1 0.0 0.1 1.5 0.1 0.0 0.5 0.1 0.0 0.0 0.1 14.9 1.9 0.0 0.1 1.1 0.1 0.0 0.1 0.6 0.0 2.2 0.1 33.9 0.0 0.0 0.0 0.3 1.7 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.4 1.6 0.0 0.9 0.2 0.0 0.0 4.5 0.0 2.7 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 17.2 27.1 13.2 32.8 24.6 23.5 15.1 24.8 11.8 14.3 18.8 10.7 0.0 0.0 3.9 24.2 0.2 0.0 0.4 0.1 0.0 33.5 0.0 0.1 12.8 0.0 1.3 0.0 16.7 0.1 0.0 0.0 0.0 0.0 11.4 2.2 1.0 1.6 0.0 0.0 126.1 0.0 0.1 0.5 0.0 0.2 0.0 0.1 0.4 1.1 0.1 37.0 103.9 0.0 0.0 0.3 2.2 13.6 0.3 0.4 0.0 7.5 0.0 10.0 0.0 80.9 5.9 0.0 0.0 0.4 0.0 0.3 0.0 4.2 4.8 18.3 0.0 0.7 0.8 5.0 1.5 0.0 3.1 0.0 0.2 0.0 0.0 0.2 ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 70.4;Fibroblasts: 115.9;Leydig cells: 110.6;Peritubular cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 97.6;BJ: 143.7;fHDF/TERT166: 205.6;U-2197: 817.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" 147.2 21.6 11.6 40.8 14.3 0.1 94.2 19.9 17.6 100.2 24.3 57.6 8.8 73.6 18.4 53.0 70.7 76.7 184.1 13.1 15.3 12.8 13.4 214.1 14.5 15.4 20.1 37.0 90.9 2.8 24.9 58.9 13.8 106.4 11.3 2.8 66.9 35.1 17.9 91.3 40.6 90.0 14.9 40.9 63.2 13.1 14.0 5.1 48.4 16.9 4.5 85.3 84.3 17.9 0.0 2.0 0.8 0.0 97.6 0.6 0.6 143.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 205.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.6 0.6 8.3 0.8 0.8 0.4 58.0 1.0 0.0 0.0 28.0 68.9 0.0 1.2 0.1 10.0 0.6 0.0 0.0 0.2 0.3 817.9 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 14.3 19.9 17.6 13.1 15.3 15.4 20.1 13.8 14.9 14.0 17.9 34.6 0.0 6.4 34.9 0.1 11.0 13.5 33.9 4.0 2.8 0.9 1.1 9.7 2.8 4.3 7.3 2.1 0.1 0.3 0.2 0.0 0.3 3.5 3.5 70.4 28.4 1.8 0.0 4.6 3.9 0.3 115.9 7.1 2.3 0.0 0.2 47.2 4.2 0.5 6.7 8.1 1.3 0.0 0.6 20.4 7.5 110.6 1.2 14.2 23.4 0.0 15.9 0.0 14.1 18.5 1.1 0.2 148.2 0.4 1.4 0.0 0.1 3.0 0.8 0.0 12.2 34.1 1.1 1.2 2.1 10.9 0.1 1.2 0.6 0.2 1.1 ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: AB_2683173" "unprognostic (5.23e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" 78.5 54.7 77.2 39.8 115.6 52.9 66.6 121.1 116.9 57.1 61.4 63.9 51.6 46.5 30.6 176.6 38.9 42.4 47.2 76.8 93.2 59.7 45.8 59.6 40.1 152.0 110.1 28.9 55.4 46.2 27.2 51.0 140.7 58.7 48.6 8.4 72.7 48.8 24.1 201.9 55.4 50.8 114.8 57.1 70.6 18.6 107.7 22.2 66.8 28.0 55.7 68.5 86.8 165.7 108.0 119.5 22.6 44.8 148.4 138.2 70.2 125.2 154.5 153.5 122.4 105.9 182.5 73.9 94.3 193.6 130.3 119.4 79.7 152.2 93.2 94.6 53.9 96.6 77.3 77.1 128.2 84.2 98.0 106.2 168.2 180.9 198.4 114.8 155.0 27.7 68.1 54.8 178.5 79.5 19.9 69.5 33.5 136.9 120.2 43.6 59.9 89.7 195.5 128.7 27.4 28.8 73.7 258.4 105.8 66.8 121.2 82.4 132.2 129.7 82.5 161.2 161.3 26.6 31.2 35.4 127.8 85.2 120.1 134.9 189.6 172.7 105.1 180.0 93.4 109.0 98.4 103.2 212.8 94.2 63.5 88.0 133.0 114.7 179.6 148.8 113.8 203.1 77.2 115.6 121.1 116.9 76.8 93.2 152.0 110.1 140.7 114.8 107.7 165.7 44.0 19.2 12.5 7.5 28.1 15.6 25.9 61.1 29.6 5.7 60.3 37.5 4.7 34.3 40.2 40.5 10.4 93.4 36.0 114.0 7.9 91.5 3.4 22.9 26.3 43.6 19.2 67.8 3.8 100.1 127.4 26.1 48.4 45.2 21.0 52.6 24.7 16.7 74.9 3.3 3.4 33.8 46.8 46.3 37.5 4.6 20.2 41.5 12.4 7.5 92.5 13.7 32.0 3.0 66.1 133.3 63.9 25.6 19.0 44.7 66.0 23.3 14.5 9.5 19.7 10.0 39.7 8.4 11.2 70.1 31.0 95.9 31.5 50.8 47.2 49.2 ELOVL3 CIG-30 ENSG00000119915 "ELOVL fatty acid elongase 3" Q9HB03 10 102226299-102229589 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 30.5" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Breast myoepithelial cells: 3.2;Skeletal myocytes: 5.0;Spermatogonia: 3.4;Theca cells: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "classical monocyte: 7.1;intermediate monocyte: 2.4;myeloid DC: 2.0;non-classical monocyte: 5.9" "Group enriched" "Detected in many" 10 "dendritic cells: 2.0;monocytes: 7.1" "Cell line enhanced" "Detected in many" "ASC diff: 9.5;ASC TERT1: 9.4;HSkMC: 13.9;NB-4: 11.6;SiHa: 22.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA036236 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" "HPA036236: AB_10601550" "unprognostic (1.52e-2)" "unprognostic (6.76e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (6.25e-5)" "unprognostic (8.23e-3)" "unprognostic (9.82e-2)" "unprognostic (2.17e-4)" "unprognostic (4.27e-2)" "unprognostic (2.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (5.36e-3)" "unprognostic (2.66e-9)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" 3.2 0.7 1.0 0.3 0.8 1.8 3.5 0.5 1.3 0.1 0.3 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.2 1.0 0.4 0.8 0.0 1.0 0.1 0.4 0.9 0.1 0.0 0.1 0.0 0.9 0.4 0.2 0.1 0.1 0.3 0.1 0.2 30.5 0.2 0.0 0.4 0.8 0.1 1.2 0.4 0.0 0.0 0.3 0.0 0.2 0.3 0.5 3.2 0.2 0.2 7.8 9.5 9.4 2.8 0.1 0.3 0.4 0.5 0.5 3.0 0.0 0.3 0.0 0.0 0.1 5.9 0.1 0.5 0.0 0.0 0.2 0.4 0.8 0.3 0.0 0.1 13.9 1.6 3.6 0.0 0.0 0.0 0.9 0.1 3.5 0.8 0.0 0.0 11.6 0.1 1.1 1.0 0.0 5.1 0.0 2.0 0.1 0.0 0.4 22.6 0.9 0.7 0.6 8.1 2.7 0.0 1.5 0.0 0.3 0.3 0.5 7.2 0.0 3.4 6.5 0.0 0.0 7.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.4 0.0 5.9 0.0 0.0 1.7 1.0 0.8 0.5 1.3 1.0 0.4 0.4 0.9 0.4 0.4 0.4 0.5 2.5 0.0 1.1 0.0 0.2 0.4 0.5 0.6 0.6 0.0 1.1 3.2 0.3 0.0 0.5 0.0 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 1.3 1.9 0.0 0.0 0.3 0.0 0.7 1.3 0.0 0.2 0.0 0.0 1.4 0.4 0.2 0.0 0.0 0.2 0.0 1.5 0.8 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 5.0 1.2 0.1 3.4 0.6 0.1 0.3 0.3 2.2 0.2 0.1 ELOVL5 "dJ483K16.1, HELO1, SCA38" ENSG00000012660 "ELOVL fatty acid elongase 5" Q9NYP7 6 53267398-53349179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017042, HPA047752, HPA054197" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" "Endoplasmic reticulum" "CAB017042: , HPA047752: AB_2680147, HPA054197: AB_2682413" "unprognostic (7.33e-2)" "unprognostic (5.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (3.06e-1)" "unprognostic (2.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.43e-2)" "unprognostic (3.23e-1)" "unprognostic (6.40e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (2.76e-2)" 242.4 134.7 51.3 74.9 67.0 114.6 199.2 74.6 79.2 48.9 49.4 40.0 28.3 39.8 49.7 28.4 46.0 51.3 37.8 50.8 65.3 38.9 108.9 68.4 106.7 80.7 69.0 32.3 15.4 24.3 28.5 40.2 74.5 128.0 18.3 36.5 24.8 103.0 9.9 32.9 47.5 52.4 67.7 56.1 22.8 82.5 65.8 107.3 45.1 19.5 102.4 67.1 27.0 98.9 137.2 98.1 168.0 309.0 436.0 250.8 71.3 155.8 174.2 123.2 171.5 87.4 154.5 154.4 110.3 163.3 193.1 78.9 168.0 142.6 183.7 131.2 117.5 153.1 85.0 122.9 239.0 122.2 107.2 233.6 109.8 123.6 153.9 124.5 139.1 301.4 194.2 87.3 90.3 14.9 364.4 107.9 91.2 5.2 73.6 139.9 115.3 54.3 232.7 80.6 155.7 107.1 129.3 66.9 135.2 108.7 152.3 112.9 133.0 134.7 118.5 242.2 208.8 72.8 72.1 116.2 70.2 173.6 97.8 47.6 49.2 183.7 34.9 34.9 56.5 88.4 58.1 42.7 77.9 101.5 27.8 26.3 261.5 36.7 45.0 20.4 110.0 50.6 51.3 67.0 74.6 79.2 50.8 65.3 80.7 69.0 74.5 67.7 65.8 98.9 48.6 80.1 50.7 75.4 118.3 52.4 108.2 36.8 44.3 11.6 177.3 70.9 23.3 21.5 40.2 12.9 2.1 25.3 55.5 2.1 15.6 34.9 94.2 37.4 53.2 54.4 25.0 77.0 25.8 36.1 58.2 54.8 3.1 66.4 99.0 28.4 39.3 88.7 35.5 8.4 29.8 1.6 16.2 57.3 114.6 181.0 20.8 55.5 48.0 39.4 53.5 83.2 39.1 49.3 111.2 27.8 1.4 32.0 45.2 169.2 21.9 48.4 58.5 6.0 65.7 27.3 77.5 27.0 18.9 35.7 60.9 31.2 97.2 60.0 4.4 73.4 ELOVL7 FLJ23563 ENSG00000164181 "ELOVL fatty acid elongase 7" A1L3X0 5 60751791-60844274 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 190.2;Oligodendrocytes: 90.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.9;neutrophil: 1.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "GAMG: 41.9;HDLM-2: 29.3;HEL: 37.3" "Low region specificity" "Detected in all" HPA036337 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "HPA036337: AB_10670797" "unprognostic (6.34e-2)" "unprognostic (1.96e-2)" "unprognostic (1.51e-2)" "prognostic unfavorable (3.87e-5)" "unprognostic (3.84e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.54e-9)" "unprognostic (6.95e-2)" "unprognostic (1.01e-3)" "unprognostic (2.94e-1)" "unprognostic (6.30e-3)" 10.5 5.5 23.1 2.2 24.9 1.0 22.1 29.5 26.5 3.6 36.2 8.8 11.8 2.2 0.9 5.0 2.8 19.3 0.9 18.3 30.0 16.2 1.0 3.8 2.5 31.8 26.3 0.5 8.5 21.0 2.7 0.8 32.9 22.0 11.5 10.5 4.7 1.2 0.5 26.2 21.3 3.7 30.1 0.5 3.3 0.8 32.9 1.8 16.8 1.0 4.0 7.6 6.7 32.2 20.7 7.6 0.1 0.5 0.0 0.0 18.6 0.0 4.3 2.5 8.4 9.6 21.4 0.0 9.1 0.0 41.9 1.2 11.9 8.3 3.8 29.3 6.9 37.3 0.9 3.2 0.2 3.0 15.2 0.1 14.6 0.3 12.3 0.9 0.0 6.5 5.9 7.2 0.0 17.8 0.1 0.3 2.4 1.9 0.1 1.6 1.9 1.2 19.4 18.5 7.8 1.2 10.9 8.8 5.0 2.0 14.2 0.6 0.2 1.5 9.0 0.2 7.2 18.5 19.7 0.3 13.2 0.8 0.4 1.9 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 2.5 23.1 24.9 29.5 26.5 18.3 30.0 31.8 26.3 32.9 30.1 32.9 32.2 14.5 12.8 3.1 4.9 0.5 31.1 13.1 1.4 4.6 2.3 3.1 1.4 0.7 20.0 4.8 12.9 0.0 0.2 0.3 8.8 5.9 6.8 0.1 6.5 1.6 21.1 4.8 1.3 29.5 3.1 0.0 2.0 5.6 20.4 12.7 0.4 0.4 0.0 0.1 0.0 26.0 17.0 0.0 0.0 16.6 0.0 0.0 4.9 10.6 190.2 2.0 3.5 0.0 6.0 90.8 7.1 13.3 0.0 0.1 23.4 29.7 8.9 1.7 6.7 0.0 1.0 0.8 0.2 1.1 2.9 38.2 2.9 0.9 0.2 15.9 8.6 EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Adipocytes: 409.0;Endothelial cells: 261.7;Hepatic stellate cells: 175.3;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" NA NA 470000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" 46.3 20.2 6.7 9.6 7.1 0.2 38.2 7.1 11.2 37.1 7.8 10.3 6.8 27.9 9.9 12.7 19.2 31.4 38.5 6.3 7.5 79.7 7.5 48.4 6.6 8.1 7.0 6.9 6.2 19.2 9.6 0.8 9.0 12.7 8.1 1.5 9.2 25.6 18.5 9.0 8.3 38.8 7.0 3.5 8.2 2.3 9.4 8.7 43.6 40.2 4.9 24.9 13.9 7.4 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.0 30.6 0.0 0.0 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 7.1 7.1 11.2 6.3 7.5 8.1 7.0 9.0 7.0 9.4 7.4 409.0 6.4 6.0 0.3 14.0 16.6 0.5 0.1 6.2 0.1 2.1 3.0 14.1 0.0 0.7 0.0 0.0 0.1 1.7 0.0 0.0 0.1 0.7 0.6 0.6 261.7 0.0 8.0 1.3 0.0 0.0 16.2 0.0 0.3 0.0 0.1 175.3 1.1 0.2 0.0 0.2 0.0 0.0 5.5 21.4 1.3 1.2 1.7 16.0 111.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 2.6 1.0 0.0 0.2 0.0 0.4 0.0 5.8 21.4 0.2 0.5 1.1 14.6 0.3 2.4 0.7 0.0 1.0 EME1 "FLJ31364, MMS4L, SLX2A" ENSG00000154920 "Essential meiotic structure-specific endonuclease 1" Q96AY2 17 50373220-50381483 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.4;epididymis: 6.3;testis: 5.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.6;Extravillous trophoblasts: 4.8;Granulosa cells: 4.5;Spermatocytes: 13.2;Spermatogonia: 9.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "basophil: 18.6" "Lineage enriched" "Detected in single" 33 "granulocytes: 18.6" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016127, HPA052188" Supported Approved "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Cytosol" "CAB016127: AB_2278026, HPA052188: " "unprognostic (3.81e-1)" "unprognostic (7.72e-2)" "unprognostic (6.49e-2)" "unprognostic (2.45e-3)" "unprognostic (2.74e-1)" "unprognostic (1.94e-2)" "unprognostic (9.94e-5)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.02e-2)" "unprognostic (4.37e-3)" "unprognostic (2.83e-3)" "unprognostic (0.00e+0)" "unprognostic (9.82e-2)" "unprognostic (1.26e-1)" "unprognostic (3.71e-1)" "unprognostic (3.41e-1)" 0.5 0.3 0.2 1.7 0.3 4.4 0.6 0.1 0.4 0.5 0.0 0.9 0.8 0.4 6.3 1.1 0.3 0.3 0.2 0.1 0.1 0.2 0.4 0.4 2.3 0.3 0.2 0.5 0.2 0.1 0.1 1.4 0.3 0.2 1.3 0.4 0.5 0.1 0.2 1.1 0.7 0.6 0.1 0.9 0.5 5.7 0.3 3.3 0.2 0.0 2.6 0.4 0.5 0.4 13.9 20.0 26.2 13.7 1.2 2.6 18.8 14.2 5.4 19.3 17.7 31.7 11.0 11.0 18.3 5.7 12.0 10.7 24.5 11.3 27.3 21.7 19.3 26.3 23.3 14.8 0.1 10.9 8.4 0.5 0.8 22.3 9.2 2.6 4.5 31.2 16.3 25.6 11.6 15.2 25.0 13.9 15.1 14.2 13.6 25.5 50.7 15.4 4.3 5.6 10.1 20.2 8.7 4.8 8.1 20.9 16.8 12.3 3.1 24.8 14.9 16.6 19.7 16.0 17.4 10.5 7.8 12.2 15.6 18.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.3 0.1 0.4 0.1 0.1 0.3 0.2 0.3 0.1 0.3 0.4 0.1 0.0 1.1 0.3 0.8 0.1 0.3 0.5 0.6 1.5 0.5 0.3 0.4 0.0 0.7 0.0 0.0 4.6 0.5 0.6 0.0 0.3 0.5 0.8 0.7 0.4 0.0 3.8 0.1 0.0 4.8 0.8 2.0 0.5 0.0 4.5 0.0 0.3 2.2 0.0 0.1 0.9 0.0 0.0 1.4 0.6 0.6 0.8 0.0 0.0 1.0 0.5 1.0 0.0 0.3 0.1 0.0 0.0 2.5 0.1 0.1 0.0 0.9 0.3 0.0 0.6 1.0 13.2 9.1 1.5 0.1 1.1 0.5 0.6 1.3 0.2 EMID1 "EMI5, EMU1, hEmu1" ENSG00000186998 "EMI domain containing 1" Q96A84 22 29205896-29259597 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.5;lymphoid tissue: 54.8" "Cell type enhanced" "Detected in many" "Astrocytes: 92.1;Granulosa cells: 32.7;Oligodendrocyte precursor cells: 51.8;Theca cells: 151.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 23.1;glioma: 7.8;ovarian cancer: 10.9;thyroid cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HEL: 28.8;NB-4: 102.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000592 Uncertain "Secreted in other tissues" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "HPA000592: AB_1078737" "unprognostic (2.20e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-2)" "unprognostic (7.80e-3)" "unprognostic (2.40e-2)" "unprognostic (1.42e-1)" "unprognostic (3.46e-1)" "unprognostic (6.25e-3)" "unprognostic (3.75e-2)" "unprognostic (2.33e-1)" "unprognostic (5.24e-3)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "unprognostic (3.09e-2)" "unprognostic (1.08e-1)" 2.6 29.0 34.5 4.2 35.0 14.8 2.5 27.7 49.5 6.5 24.4 5.7 5.1 10.0 1.7 1.3 10.4 4.8 2.3 36.8 29.4 15.0 3.3 13.0 7.5 30.1 30.4 7.0 14.0 12.4 2.0 4.9 28.3 6.1 3.4 0.3 3.6 3.9 0.8 6.3 8.3 2.3 27.0 54.8 7.7 2.3 27.8 4.8 13.2 0.3 2.3 4.9 2.2 32.4 0.0 0.2 4.9 10.5 0.0 0.0 0.7 0.0 0.0 0.4 0.3 5.7 0.7 0.0 4.7 0.1 0.0 0.0 2.5 0.1 0.0 11.5 8.6 28.8 0.1 1.1 0.7 4.1 2.2 0.3 0.2 0.2 0.0 0.0 0.0 6.4 2.5 0.0 0.0 8.0 0.2 102.0 1.1 0.1 0.4 0.0 0.2 11.3 0.0 0.1 13.2 6.3 0.4 0.1 0.2 0.8 4.2 5.4 0.0 0.0 8.0 0.0 0.1 0.5 0.0 0.0 0.0 14.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 34.5 35.0 27.7 49.5 36.8 29.4 30.1 30.4 28.3 27.0 27.8 32.4 0.4 0.0 2.5 92.1 0.1 2.8 1.0 0.1 0.0 1.7 5.3 3.9 0.7 4.3 0.6 0.0 0.0 0.1 0.2 0.0 0.0 1.2 0.2 10.8 22.6 6.2 0.0 18.5 5.6 1.3 0.1 11.8 0.5 20.0 11.4 32.7 11.4 2.1 0.3 0.0 6.2 0.4 0.0 0.3 5.2 0.5 3.1 0.6 0.0 10.3 0.6 1.1 0.0 51.8 1.0 0.4 0.0 1.9 1.0 1.9 0.1 1.9 0.0 0.4 0.0 17.5 4.0 0.1 1.5 0.0 2.0 0.3 1.1 151.0 0.3 0.4 EMILIN2 "FLJ33200, FOAP-10" ENSG00000132205 "Elastin microfibril interfacer 2" Q9BXX0 18 2847006-2916003 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 76.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 98.0;Hofbauer cells: 61.1;Kupffer cells: 52.9;Langerhans cells: 99.7;Macrophages: 97.5;monocytes: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 5.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.2;BEWO: 37.8;HL-60: 37.8;HMC-1: 60.6;HSkMC: 26.1;SuSa: 25.7;THP-1: 36.7;U-2197: 46.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 25.7" HPA064576 Supported "Secreted to extracellular matrix" NA NA 840000 "Cluster 41: Basophils - Cellular respiration" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA064576: AB_2732717" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (7.91e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-3)" "unprognostic (9.91e-3)" "prognostic unfavorable (6.30e-4)" "unprognostic (2.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.49e-1)" "unprognostic (3.15e-3)" "unprognostic (3.72e-2)" "unprognostic (2.96e-1)" 13.0 1.3 1.2 17.2 2.2 11.3 5.1 4.8 1.7 5.3 2.2 2.8 1.6 6.4 0.8 2.4 4.7 5.9 6.8 0.7 1.2 1.1 1.5 11.9 2.4 8.1 4.4 5.9 1.4 76.0 0.4 21.9 5.8 1.0 3.3 0.1 2.3 1.2 0.8 2.7 2.2 8.4 6.6 3.9 1.6 1.8 7.4 2.9 1.6 2.4 2.0 8.0 4.0 10.6 0.2 0.4 2.9 0.0 48.2 19.9 37.8 7.9 0.0 1.4 2.4 5.6 0.1 0.0 0.6 19.3 0.5 0.1 1.0 0.0 2.6 0.0 2.6 0.5 0.2 0.4 1.6 37.8 60.6 26.1 0.0 1.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.1 10.4 4.9 0.4 0.1 0.1 2.5 0.0 0.1 0.2 0.4 0.2 0.2 0.3 1.4 25.7 0.0 36.7 0.4 0.0 5.2 46.7 0.4 0.0 0.0 0.0 3.1 9.1 1.0 5.5 1.1 0.3 0.4 0.8 0.3 0.2 0.4 0.3 1.1 0.3 0.2 0.4 1.1 1.5 0.7 0.7 0.3 0.4 1.2 2.2 4.8 1.7 0.7 1.2 8.1 4.4 5.8 6.6 7.4 10.6 6.8 3.2 6.7 0.0 13.7 5.7 3.3 0.5 0.6 0.1 2.8 3.0 15.7 1.5 5.3 3.7 0.0 4.7 14.5 2.8 1.9 2.7 2.3 19.3 98.0 8.8 3.0 6.7 0.5 1.1 11.9 31.4 5.6 46.0 46.3 5.7 2.9 0.5 61.1 0.0 1.2 4.9 0.0 52.9 99.7 2.3 15.2 97.5 5.4 2.8 51.0 0.0 7.2 11.1 9.1 2.4 7.9 1.2 2.7 3.5 1.5 1.7 4.0 0.2 0.0 2.3 8.7 4.9 5.5 0.4 4.0 2.9 9.6 14.7 5.1 2.8 EMILIN3 "C20orf130, dJ620E11.4, EMILIN5" ENSG00000183798 "Elastin microfibril interfacer 3" Q9NT22 20 41359962-41366818 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 53.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 17.7;Granulosa cells: 7.6;Microglial cells: 4.7;Oligodendrocyte precursor cells: 3.5;Peritubular cells: 4.9;Skeletal myocytes: 3.2" "Group enriched" "Detected in many" 5 "glioma: 10.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.3;HAP1: 11.1;NTERA-2: 7.0;SCLC-21H: 13.0" "Region enriched" "Detected in single" 30 "cerebellum: 3.3" "Region enriched" "Detected in single" 4 "spinal cord: 4.1" "HPA044034, HPA059912, HPA078559" Enhanced Approved "Golgi apparatus,Microtubules,Cytokinetic bridge" "Secreted to extracellular matrix" Yes NA 1200000 "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" "Microtubules, Cytokinetic bridge" "HPA044034: AB_2678783, HPA059912: AB_2684158, HPA078559: " "unprognostic (1.66e-4)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.14e-1)" "unprognostic (2.65e-1)" "unprognostic (2.15e-2)" "unprognostic (1.71e-1)" "unprognostic (7.66e-2)" "unprognostic (2.18e-3)" "unprognostic (2.57e-1)" "unprognostic (6.54e-2)" "unprognostic (7.66e-2)" "unprognostic (3.13e-7)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.97e-1)" "unprognostic (9.62e-2)" 0.6 1.4 2.5 0.1 2.4 0.0 3.5 2.3 3.8 8.6 1.8 4.9 0.6 2.3 53.6 0.8 4.2 0.3 7.8 2.1 2.2 1.0 0.6 0.3 0.1 3.7 2.7 8.9 0.2 0.1 1.8 0.0 3.0 6.7 0.3 0.0 1.0 9.9 0.9 3.9 1.7 0.9 2.5 0.1 2.0 1.7 2.6 0.5 0.3 2.6 0.2 2.3 4.7 3.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 11.1 0.0 0.2 0.0 1.3 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.0 1.3 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.4 2.3 3.8 2.1 2.2 3.7 2.7 3.0 2.5 2.6 3.0 0.6 0.0 0.0 0.7 0.0 0.9 0.2 0.0 0.0 0.3 1.2 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 17.7 0.4 0.0 0.0 1.1 0.0 0.0 0.8 0.0 0.7 0.0 7.6 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 1.8 0.1 0.0 4.7 0.0 0.1 0.0 3.5 0.1 0.0 1.2 4.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 3.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 EML2 "ELP70, EMAP-2, EMAP2" ENSG00000125746 "EMAP like 2" O95834 19 45606994-45645602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 153.1;Syncytiotrophoblasts: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012757 Approved Approved Vesicles NA NA 180000 "Cluster 27: Non-specific - Gene expression" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA012757: AB_1848145" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.81e-3)" "unprognostic (1.13e-1)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.85e-1)" "unprognostic (3.05e-3)" "unprognostic (3.72e-1)" "unprognostic (2.75e-3)" "unprognostic (1.77e-1)" "unprognostic (2.85e-2)" "unprognostic (9.44e-2)" "unprognostic (7.48e-2)" "unprognostic (7.03e-2)" 11.2 32.7 23.2 13.6 41.7 14.1 12.9 43.2 37.6 16.4 9.7 21.3 11.5 9.1 6.8 40.2 12.0 10.9 20.4 19.5 36.1 17.5 7.9 13.6 13.4 57.6 35.4 5.2 21.1 55.1 14.3 19.8 52.8 15.8 14.4 49.0 29.0 18.3 5.7 38.6 11.9 7.1 27.9 12.9 18.9 3.5 40.3 16.5 20.9 4.9 12.5 19.5 24.9 57.9 47.6 16.2 3.2 1.1 25.0 13.6 17.4 29.2 37.0 12.6 14.8 6.2 39.5 14.6 17.0 15.4 4.0 39.7 6.0 57.4 4.0 56.7 15.0 5.7 19.5 12.4 47.1 18.5 13.4 21.1 74.5 15.1 74.1 10.5 9.4 28.0 18.3 38.5 10.0 49.9 10.3 4.2 1.9 75.7 14.3 2.3 5.6 18.9 33.3 61.2 17.8 3.3 16.4 32.0 22.1 17.0 18.7 18.9 15.1 0.0 5.4 4.8 0.3 66.2 43.9 7.9 20.4 20.9 38.7 7.8 3.7 5.7 6.5 4.8 5.1 5.5 4.4 6.7 4.4 2.2 2.9 3.9 1.0 2.6 5.2 6.4 5.8 3.9 23.2 41.7 43.2 37.6 19.5 36.1 57.6 35.4 52.8 27.9 40.3 57.9 10.6 3.2 13.1 8.5 15.7 18.6 42.9 40.3 27.3 32.2 13.2 14.2 9.0 14.3 25.5 35.0 14.6 66.4 24.5 34.1 37.2 16.8 72.1 28.6 9.0 13.8 17.5 5.5 29.7 20.8 20.4 7.6 38.7 20.1 19.1 6.7 20.3 6.4 15.8 28.6 46.0 32.6 26.4 8.8 9.6 27.0 4.1 8.7 19.6 5.6 13.1 16.4 12.3 15.1 68.0 17.9 29.1 7.2 25.0 23.7 11.0 7.5 40.7 153.1 0.0 6.8 16.4 3.5 6.1 29.6 14.3 101.0 23.2 39.1 31.9 41.9 EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 230.6" "Group enriched" "Detected in many" 7 "Alveolar cells type 1: 4163.5;Suprabasal keratinocytes: 1174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 268.1;RT4: 182.0;SK-BR-3: 256.2;T-47d: 156.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 42: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA014711: AB_1848147, HPA070816: " "unprognostic (1.75e-1)" "unprognostic (4.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (9.27e-2)" "unprognostic (8.90e-2)" "unprognostic (2.41e-2)" "unprognostic (4.40e-1)" "unprognostic (1.86e-1)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (2.85e-8)" "unprognostic (9.54e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (9.52e-2)" 56.8 9.7 15.5 12.4 15.5 0.7 49.5 14.8 17.1 51.0 18.6 48.0 15.5 25.9 45.5 152.1 35.5 17.7 64.1 13.6 15.6 20.3 83.2 230.6 5.7 16.1 16.8 54.9 13.7 32.8 13.3 23.0 16.0 38.8 34.1 2.0 39.2 17.3 22.5 140.6 28.3 22.3 15.2 16.0 39.1 7.2 18.8 5.3 27.7 25.4 32.8 39.6 72.9 15.7 28.7 39.1 15.9 18.9 35.0 30.0 31.3 40.0 36.8 23.9 35.7 128.5 98.2 0.2 12.6 48.4 17.2 123.9 41.1 49.8 31.3 0.1 26.1 0.1 76.6 72.1 6.1 0.2 0.4 18.4 13.1 31.9 3.2 5.4 10.1 0.1 9.6 2.6 66.9 268.1 0.4 0.6 18.3 46.4 9.5 7.5 18.2 61.7 5.5 182.0 22.0 25.0 49.6 256.2 15.2 45.2 156.6 6.2 5.7 75.5 32.2 25.6 22.7 0.8 1.0 0.2 33.2 0.5 75.7 1.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 1.1 0.3 0.3 0.3 0.2 0.1 15.5 15.5 14.8 17.1 13.6 15.6 16.1 16.8 16.0 15.2 18.8 15.7 239.7 4163.5 368.4 13.1 3.1 356.9 137.9 172.2 111.0 2.3 105.0 94.0 53.1 100.1 255.8 42.3 0.0 74.2 3.1 119.5 0.0 3.8 8.0 78.8 30.9 183.9 104.9 0.0 0.7 67.0 17.8 152.7 46.4 51.9 36.7 68.7 161.0 235.1 10.1 0.0 0.6 207.8 81.4 19.6 136.5 9.3 190.7 17.0 87.2 41.2 33.6 5.7 0.0 22.6 0.6 32.9 158.4 276.1 1.6 86.0 21.0 0.2 142.8 2.2 52.6 256.3 129.3 5.7 12.9 319.5 1174.3 48.0 9.3 73.3 178.5 221.4 EN1 ENSG00000163064 "Engrailed homeobox 1" Q05925 2 118842171-118847648 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.2;skeletal muscle: 13.9;skin 1: 10.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 5.6;Fibroblasts: 4.8;Melanocytes: 12.4;Skeletal myocytes: 12.0;Smooth muscle cells: 5.4" "Cancer enhanced" "Detected in many" "breast cancer: 5.6" "Region enriched" "Detected in many" 6 "midbrain: 18.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.1;ASC TERT1: 7.2;fHDF/TERT166: 13.3;HSkMC: 13.5;PC-3: 7.8;U-138 MG: 9.9;U-2197: 11.2" "Region enriched" "Detected in single" 5 "midbrain: 4.9" "Region enriched" "Detected in some" 6 "midbrain: 23.6" "CAB014884, HPA073141" Enhanced Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli rim" Nucleoplasm "CAB014884: , HPA073141: AB_2686573" "unprognostic (5.20e-2)" "unprognostic (1.61e-1)" "unprognostic (5.78e-2)" "unprognostic (4.84e-7)" "unprognostic (1.87e-3)" "unprognostic (1.90e-1)" "unprognostic (1.95e-3)" "unprognostic (1.16e-1)" "unprognostic (2.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.46e-1)" "unprognostic (3.38e-9)" "unprognostic (2.15e-2)" "unprognostic (1.88e-1)" "unprognostic (1.70e-1)" "unprognostic (9.30e-3)" 3.5 0.2 0.1 0.0 0.1 0.0 1.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.8 0.7 18.2 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 13.9 10.4 0.0 0.0 0.5 0.0 0.0 0.1 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.5 4.0 0.2 0.6 0.2 16.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 4.7 0.5 0.6 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.1 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.3 0.0 0.0 0.0 9.9 1.0 11.2 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.5 0.7 18.2 3.2 0.5 1.4 0.5 1.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 5.6 2.8 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 12.4 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 5.4 0.1 0.4 0.0 2.6 0.0 0.2 0.0 0.0 0.0 ENPP5 ENSG00000112796 "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5" Q9UJA9 6 46159185-46170980 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 243.6" "Cell type enhanced" "Detected in many" "Muller glia cells: 100.1;Respiratory ciliated cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.9" "Lineage enriched" "Detected in many" 5 "T-cells: 14.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 11.1;HSkMC: 7.1;SuSa: 6.2;T-47d: 8.7;U-266/84: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016902 Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 620000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" Cytosol Nucleoplasm "HPA016902: AB_1848172" "unprognostic (1.12e-1)" "unprognostic (5.19e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-1)" "unprognostic (7.61e-2)" "unprognostic (1.63e-1)" "unprognostic (5.01e-2)" "prognostic favorable (4.57e-4)" "unprognostic (1.96e-1)" "unprognostic (9.89e-2)" "prognostic favorable (4.04e-4)" "unprognostic (7.00e-2)" "prognostic favorable (4.44e-13)" "unprognostic (4.40e-2)" "unprognostic (2.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.60e-1)" 1.8 8.6 6.2 1.1 7.6 0.2 13.4 6.9 12.6 12.8 4.0 2.6 1.5 1.8 243.6 1.8 15.4 7.0 4.4 7.0 9.7 24.3 0.5 8.8 1.2 5.8 13.0 9.7 9.7 46.3 19.8 1.7 6.2 29.4 3.2 30.6 14.4 31.0 10.7 1.6 1.9 0.9 4.5 5.7 6.7 35.5 14.0 8.2 51.0 10.3 1.4 5.6 1.8 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.5 0.1 0.3 11.1 1.8 3.6 0.2 3.7 0.0 0.6 1.5 0.1 0.0 2.4 0.7 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.4 1.9 0.0 0.5 2.3 5.4 0.0 0.0 0.2 0.2 4.5 0.6 4.7 0.2 0.0 4.6 0.0 6.2 8.7 0.0 0.0 0.0 1.2 0.0 0.1 5.3 7.9 0.0 2.8 0.0 0.1 0.0 0.0 0.0 14.9 0.1 8.0 0.5 3.0 9.7 0.0 0.8 0.9 8.7 1.1 2.8 0.0 0.0 0.0 3.2 6.2 7.6 6.9 12.6 7.0 9.7 5.8 13.0 6.2 4.5 14.0 6.3 0.4 12.8 12.2 16.3 1.6 0.9 4.8 0.5 1.2 10.6 18.1 10.8 7.5 8.6 6.1 23.9 4.2 4.9 4.2 1.9 1.9 11.6 0.7 15.3 0.8 0.4 8.3 0.0 24.6 7.5 2.9 4.2 2.0 5.4 4.5 4.0 0.4 0.1 0.4 10.1 14.5 2.8 2.0 0.0 0.4 3.8 2.8 0.5 0.0 1.9 0.6 100.1 23.7 9.0 10.5 2.2 2.3 12.0 0.1 12.0 1.7 16.3 47.3 3.4 6.6 25.7 1.8 0.5 2.4 1.1 0.6 0.3 3.2 21.2 2.9 3.3 ENSA "ARPP-19e, MGC4319, MGC78563, MGC8394" ENSG00000143420 "Endosulfine alpha" O43768 1 150600851-150629612 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 11 "U-698: 8664.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051294 Uncertain Approved Nucleoplasm,Nucleoli,Microtubules,Cytosol NA NA 700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nucleoli" "Microtubules, Cytosol" "HPA051294: AB_2681425" "unprognostic (6.27e-2)" "prognostic favorable (8.24e-4)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (2.58e-1)" "unprognostic (8.24e-2)" "unprognostic (1.94e-3)" "unprognostic (1.82e-1)" "unprognostic (2.02e-1)" "unprognostic (1.44e-3)" "unprognostic (1.21e-1)" "unprognostic (5.40e-2)" "unprognostic (2.21e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-1)" "unprognostic (7.64e-2)" "unprognostic (8.07e-3)" 140.5 106.6 151.2 115.1 156.7 219.8 154.9 133.6 188.2 145.2 132.6 135.9 133.6 117.8 183.3 288.0 100.5 94.9 120.2 161.6 144.1 118.8 148.8 124.0 128.4 137.2 135.6 102.4 108.5 173.0 92.0 103.7 134.2 97.7 123.9 121.8 122.9 94.6 301.0 241.3 132.7 105.8 136.9 99.7 124.1 45.2 147.4 157.8 134.4 212.3 146.7 147.0 165.6 157.0 287.1 170.8 236.9 206.9 149.7 126.8 220.7 141.0 148.4 199.9 171.7 207.3 216.6 288.9 196.8 122.1 125.1 238.3 198.5 325.4 160.1 415.1 277.4 434.3 239.6 158.2 108.3 372.1 462.6 100.5 202.0 214.1 293.6 118.8 206.2 224.8 321.7 551.8 140.9 775.5 302.3 272.6 431.2 386.2 211.1 298.6 199.9 328.0 299.2 306.0 303.8 193.3 201.6 385.6 222.1 200.8 533.9 442.9 208.2 143.9 261.9 171.8 340.3 309.4 441.4 8664.2 197.1 357.6 191.8 67.3 54.4 94.3 55.6 62.9 52.2 64.3 46.3 57.5 70.7 55.3 37.7 56.0 53.0 68.8 64.3 58.3 58.2 75.1 151.2 156.7 133.6 188.2 161.6 144.1 137.2 135.6 134.2 136.9 147.4 157.0 103.1 41.7 166.1 20.9 132.9 190.3 225.1 303.9 124.7 59.7 152.7 117.1 102.6 98.7 172.9 82.8 45.9 286.5 148.9 170.7 254.3 160.3 9.7 109.1 68.5 114.2 130.8 178.2 44.7 152.4 184.2 85.9 71.9 93.7 224.3 51.1 80.3 86.9 203.3 67.3 29.3 169.1 211.6 101.1 171.4 17.7 86.0 123.3 103.2 19.7 409.7 83.6 184.4 21.6 19.3 91.5 146.8 104.2 135.6 128.0 187.2 186.0 128.8 50.0 72.3 85.5 94.4 27.6 25.0 269.7 286.8 382.8 140.4 87.9 163.9 253.7 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 EPB41 "4.1R, EL1" ENSG00000159023 "Erythrocyte membrane protein band 4.1" P11171 1 28887091-29120046 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Actin-binding, Calmodulin-binding" "Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 80.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.6;Cone photoreceptor cells: 137.6;Erythroid cells: 187.1;Rod photoreceptor cells: 171.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 42.2" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 136.3;K-562: 136.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebellum: 105.6" "HPA028076, HPA028096, HPA028412, HPA028414" Supported Supported "Nuclear bodies,Plasma membrane,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No 1100000 "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cell Junctions" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA028076: AB_2672476, HPA028096: , HPA028412: AB_2672592, HPA028414: AB_10601366" "unprognostic (2.16e-1)" "unprognostic (1.96e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (4.58e-4)" "unprognostic (5.00e-2)" "prognostic favorable (5.87e-4)" "unprognostic (5.01e-3)" "unprognostic (5.40e-3)" "unprognostic (2.52e-2)" "unprognostic (6.65e-2)" "unprognostic (7.81e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 11.0 10.2 1.8 21.9 18.3 63.3 14.1 42.2 6.0 14.5 4.9 23.6 17.7 10.2 5.3 16.6 6.3 15.0 9.7 1.2 4.7 12.7 21.7 15.1 37.4 8.2 5.6 16.3 18.8 15.5 4.7 7.2 8.5 15.0 23.1 80.0 19.1 9.1 15.9 15.3 23.3 9.9 3.5 22.9 27.0 10.4 4.7 69.0 15.2 13.8 37.0 15.5 1.9 3.0 27.0 6.9 62.3 29.4 5.2 0.8 19.5 6.9 10.1 8.4 10.5 16.8 31.2 49.1 17.2 9.2 13.5 11.9 78.7 6.6 8.6 86.4 23.8 136.3 19.7 28.6 10.1 45.8 88.2 1.7 18.4 8.2 13.8 19.9 14.1 73.5 136.5 36.2 0.1 8.8 72.3 30.4 62.0 44.1 10.0 110.9 28.2 68.3 7.7 33.3 78.0 60.5 19.7 19.2 43.3 21.7 14.7 18.2 1.2 0.3 13.3 12.9 13.4 52.5 72.4 85.2 12.1 47.8 6.8 33.3 3.2 21.4 12.9 1.1 15.4 17.2 18.3 14.1 4.4 13.6 22.1 12.7 44.2 10.9 1.5 4.4 28.9 15.3 1.8 18.3 42.2 6.0 1.2 4.7 8.2 5.6 8.5 3.5 4.7 3.0 25.3 19.2 71.7 20.2 58.2 10.5 8.6 7.8 15.4 151.6 20.0 12.2 21.5 20.0 16.8 16.5 137.6 2.4 75.3 26.5 17.6 17.1 16.4 11.3 4.1 15.1 41.6 187.1 76.3 18.7 4.2 7.9 29.6 29.1 24.1 24.9 17.5 30.0 7.1 21.9 61.7 29.0 16.2 23.7 9.0 22.7 2.1 32.4 0.0 78.7 29.3 15.7 85.5 7.5 4.8 28.6 20.3 2.2 46.7 12.2 32.8 13.4 15.2 171.4 13.1 2.8 8.5 39.3 55.7 14.9 16.8 4.1 71.6 4.2 33.0 12.6 EPB41L4A NBL4 ENSG00000129595 "Erythrocyte membrane protein band 4.1 like 4A" Q9HCS5 5 112142441-112419313 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 64.3;Oligodendrocyte precursor cells: 164.4;Oligodendrocytes: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 30.1;HeLa: 36.5;RT4: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036580 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Nucleoplasm "HPA036580: AB_10669908" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (1.92e-3)" "unprognostic (3.64e-2)" "unprognostic (4.73e-2)" "unprognostic (5.59e-3)" "unprognostic (4.40e-2)" "unprognostic (8.38e-2)" "unprognostic (1.90e-1)" "unprognostic (3.97e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.65e-5)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (2.73e-1)" "unprognostic (1.92e-1)" 8.7 4.5 4.8 3.2 5.7 3.6 5.3 4.1 4.8 4.1 9.0 4.0 2.6 4.3 12.7 10.1 7.4 13.8 9.2 6.0 5.1 11.7 3.3 7.7 3.3 5.7 4.6 5.7 4.9 8.0 0.5 9.3 4.8 5.8 4.8 16.0 7.2 5.4 4.2 8.8 3.4 2.7 4.9 4.7 5.6 6.1 4.8 3.6 13.5 4.2 3.6 5.1 2.3 4.8 0.8 5.5 14.3 1.5 0.0 0.0 2.9 2.1 0.0 0.0 0.0 3.0 12.3 6.2 30.1 0.0 0.8 7.4 1.1 6.9 0.0 1.0 5.0 9.8 36.5 2.0 0.1 2.6 3.1 0.0 3.0 0.0 0.0 1.6 9.2 1.7 1.9 5.6 0.0 1.8 4.6 3.5 2.7 1.2 1.1 2.3 10.7 1.3 8.4 21.6 11.8 6.1 10.7 5.2 4.5 9.8 15.9 1.4 15.7 0.7 2.4 1.9 4.4 5.6 1.3 4.6 1.4 5.2 0.8 0.5 0.2 0.1 2.0 0.3 1.1 1.4 0.6 0.6 0.2 1.6 0.9 1.8 0.2 0.1 0.5 0.1 0.6 0.5 4.8 5.7 4.1 4.8 6.0 5.1 5.7 4.6 4.8 4.9 4.8 4.8 55.9 28.9 7.7 17.3 4.7 6.0 16.8 11.2 13.6 5.0 11.2 4.7 8.3 64.3 24.2 14.7 4.2 7.4 4.5 8.5 11.7 15.0 20.8 19.7 3.1 35.2 1.2 2.1 28.6 7.5 0.7 8.4 7.1 17.1 8.8 11.9 34.6 1.7 2.7 1.7 31.8 6.3 16.2 4.6 2.1 23.0 1.8 1.8 3.6 56.2 3.2 8.2 14.4 164.4 65.4 14.1 10.9 1.9 6.5 13.7 1.9 30.4 39.5 32.1 0.0 8.7 6.0 1.8 9.1 16.0 8.1 2.5 3.7 2.2 7.5 19.1 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.6;parathyroid gland: 69.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 138.6;Inhibitory neurons: 172.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 12.0;HEK 293: 35.1;RH-30: 31.7;THP-1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010496 Approved "Intracellular and membrane" NA NA 660000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" 0.3 0.0 1.2 0.4 3.4 0.0 1.2 3.4 5.1 1.4 0.0 24.6 1.5 0.9 0.2 0.2 0.5 2.2 3.6 4.9 2.6 5.9 0.0 0.2 0.0 1.2 2.2 1.9 0.1 69.9 1.2 0.4 1.5 9.7 2.5 1.8 5.4 0.9 0.1 0.2 4.4 2.1 0.4 3.9 10.3 0.9 0.6 0.0 0.1 0.1 0.0 8.2 1.8 1.2 0.0 0.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 35.1 0.0 3.0 0.0 0.0 0.0 0.0 0.5 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.6 0.0 1.0 5.4 31.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.4 3.4 5.1 4.9 2.6 1.2 2.2 1.5 0.4 0.6 1.2 0.2 0.0 0.0 4.2 0.0 0.4 0.4 0.0 0.6 18.5 3.1 1.8 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 13.1 1.3 1.4 1.8 0.0 0.0 138.6 0.0 0.0 5.9 0.0 3.8 0.0 3.7 0.0 0.0 0.1 11.8 172.0 0.0 0.0 0.0 0.4 3.3 0.9 0.1 0.0 11.2 0.0 0.4 0.0 4.5 8.3 0.1 0.0 0.0 0.0 0.4 0.0 11.8 0.0 1.0 0.0 0.2 0.5 0.2 1.1 0.2 1.0 0.0 0.2 0.9 0.0 0.1 EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6" "Cell type enhanced" "Detected in many" "Astrocytes: 198.8;dendritic cells: 53.7;Early spermatids: 42.2;Excitatory neurons: 47.9;Inhibitory neurons: 44.3;Late spermatids: 41.2;Oligodendrocyte precursor cells: 77.9" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 33 "neutrophil: 24.0;plasmacytoid DC: 23.3" "Group enriched" "Detected in many" 33 "dendritic cells: 23.3;granulocytes: 24.0" "Group enriched" "Detected in some" 5 "HDLM-2: 63.9;HMC-1: 35.5;RPTEC TERT1: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: AB_2685895" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" 1.0 0.6 4.7 0.8 18.7 0.7 3.2 40.6 12.8 1.8 0.0 3.2 1.4 2.2 0.9 1.9 1.3 1.7 0.3 7.0 5.1 1.3 1.6 0.3 1.9 5.0 14.4 0.7 0.3 0.2 1.0 0.2 5.5 1.7 0.5 4.2 2.2 2.7 4.9 4.8 0.7 0.7 0.9 1.9 0.6 10.8 12.0 0.7 7.0 10.3 1.7 1.5 1.0 4.2 0.0 0.0 8.4 0.1 0.2 0.0 0.0 6.6 0.1 0.3 0.1 0.1 0.0 1.1 1.6 3.4 0.6 0.1 5.5 0.0 1.2 63.9 0.8 4.8 0.0 0.0 0.0 0.0 35.5 0.1 0.0 0.1 0.0 0.3 0.2 0.5 0.0 0.3 4.7 0.2 0.0 0.3 2.4 1.2 0.1 0.0 0.9 0.2 16.5 0.0 1.1 0.2 0.0 0.1 0.0 1.1 0.1 0.7 0.5 1.1 3.4 0.7 7.9 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 23.3 0.0 0.2 4.7 18.7 40.6 12.8 7.0 5.1 5.0 14.4 5.5 0.9 12.0 4.2 1.9 0.0 0.0 198.8 1.0 3.7 0.0 0.0 0.0 1.9 0.8 12.3 1.6 0.0 0.0 0.0 10.4 0.0 53.7 0.0 0.0 0.8 42.2 0.1 0.5 2.8 0.0 0.0 47.9 0.4 0.1 0.4 0.0 0.1 0.0 3.3 0.4 7.0 0.4 0.0 44.3 0.0 0.0 0.0 0.8 41.2 0.6 0.8 1.8 8.4 0.1 16.9 0.0 77.9 5.6 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.0 3.3 0.8 0.5 1.6 0.0 5.8 0.0 0.2 3.0 0.3 0.2 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPHX2 ABHD20 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490781-27545564 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 333.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 180.0;Hepatocytes: 131.5;Proximal enterocytes: 399.0;Proximal tubular cells: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 35.0;naive CD4 T-cell: 106.7;naive CD8 T-cell: 50.4;T-reg: 29.6" "Lineage enriched" "Detected in many" 23 "T-cells: 106.7" "Cell line enhanced" "Detected in many" "JURKAT: 139.4;K-562: 51.6;OE19: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favorable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favorable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 19.3 74.0 14.5 9.1 15.0 1.9 30.1 14.4 14.1 21.0 42.2 61.4 112.8 17.7 27.2 38.6 41.6 9.4 29.1 13.2 15.3 166.3 333.2 11.2 17.2 16.1 17.3 38.0 64.5 54.8 35.8 8.5 15.9 64.6 57.6 21.5 36.5 27.2 16.2 43.4 128.4 15.4 15.8 10.8 23.4 9.0 15.8 65.9 22.6 13.8 20.8 19.7 23.4 15.7 15.3 10.1 6.3 8.1 0.4 0.0 4.8 1.3 0.9 0.7 0.2 8.0 10.1 0.1 5.9 4.1 3.2 10.7 1.1 2.6 0.5 0.0 4.7 22.5 1.1 24.8 3.4 0.1 4.5 8.6 10.7 0.1 1.1 2.5 0.5 139.4 51.6 0.2 0.0 4.7 14.9 0.5 10.1 102.4 17.2 0.1 0.1 0.4 8.7 2.2 5.1 16.0 12.1 14.2 15.0 4.6 21.8 4.2 0.2 0.0 3.8 1.8 0.1 12.5 10.1 0.2 0.4 0.1 0.1 0.1 0.1 0.0 7.8 0.0 11.3 4.5 35.0 12.7 0.1 2.5 106.7 50.4 0.2 4.6 0.1 0.2 29.6 20.0 14.5 15.0 14.4 14.1 13.2 15.3 16.1 17.3 15.9 15.8 15.8 15.7 6.3 6.4 17.0 16.3 6.1 11.9 18.6 10.1 29.6 34.1 17.2 18.4 23.7 20.0 9.7 27.6 79.2 22.8 1.0 82.7 180.0 8.8 7.5 6.9 4.8 9.4 23.4 3.8 3.0 6.4 2.5 12.1 15.8 1.5 5.7 17.4 17.5 131.5 2.2 33.7 7.2 63.4 2.0 4.6 1.2 4.8 29.8 3.6 5.4 2.8 2.6 91.5 3.1 7.5 5.1 3.1 83.7 18.8 4.5 20.5 399.0 259.3 24.1 52.4 0.0 11.5 10.2 1.3 13.9 39.2 18.3 8.2 11.9 78.5 101.3 10.8 EPHX4 "ABHD7, EH4, EPHXRP, FLJ90341" ENSG00000172031 "Epoxide hydrolase 4" Q8IUS5 1 92029985-92063538 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.9;choroid plexus: 5.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 55.3;Inhibitory neurons: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 12.1" "Lineage enriched" "Detected in single" 21 "T-cells: 12.1" "Cell line enhanced" "Detected in some" "A-431: 15.4;CAPAN-2: 13.0;EFO-21: 25.9;RPTEC TERT1: 36.1;U-251 MG: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035067 Uncertain Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035067: AB_10601465" "unprognostic (1.27e-1)" "unprognostic (4.17e-2)" "unprognostic (6.76e-3)" "unprognostic (6.10e-8)" "prognostic unfavorable (9.43e-4)" "unprognostic (5.36e-3)" "unprognostic (2.72e-4)" "unprognostic (4.85e-2)" "unprognostic (9.44e-3)" "unprognostic (7.93e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (2.53e-1)" "unprognostic (6.36e-6)" "unprognostic (6.93e-3)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" 0.5 0.5 4.0 0.5 9.2 0.0 1.4 1.9 10.9 0.9 5.7 0.6 0.6 0.6 0.5 0.8 0.4 0.4 0.5 6.9 2.3 0.4 0.0 0.6 0.2 3.1 2.3 0.1 0.0 0.4 1.1 0.8 3.1 0.9 0.5 2.1 0.2 1.8 0.1 0.5 0.4 1.1 1.8 0.0 0.3 1.2 2.8 0.0 1.8 0.1 0.2 0.7 0.2 5.5 15.4 0.5 2.9 0.0 0.0 0.0 0.7 0.3 5.5 0.5 0.3 0.0 13.0 0.0 25.9 0.0 3.9 0.2 0.5 1.2 0.5 0.0 8.0 0.0 0.1 0.0 0.2 1.1 0.0 0.9 0.7 0.0 0.0 9.4 4.5 0.0 0.1 0.0 0.4 0.9 2.2 0.6 2.8 0.0 5.2 0.5 0.3 0.0 36.1 3.0 1.8 2.2 9.1 0.0 2.9 0.2 0.0 2.2 0.2 0.0 0.1 0.0 10.9 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.1 0.0 2.0 0.1 1.4 3.0 0.0 0.0 0.3 2.8 0.0 0.5 0.0 0.0 0.0 1.5 4.0 9.2 1.9 10.9 6.9 2.3 3.1 2.3 3.1 1.8 2.8 5.5 2.0 0.0 0.0 4.9 0.0 0.1 0.1 2.0 0.0 2.0 6.7 4.6 1.0 0.0 1.5 0.0 2.1 0.4 3.2 0.1 0.0 0.4 1.7 1.0 0.1 6.2 0.0 0.0 55.3 0.9 0.7 0.3 0.0 1.3 0.0 0.3 0.4 0.0 0.2 1.7 32.5 0.0 0.0 0.0 0.4 0.1 0.0 0.2 3.6 4.7 0.1 8.6 0.0 5.5 2.7 5.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.6 0.0 0.1 0.8 6.0 0.7 0.1 0.4 0.0 1.1 0.2 0.3 0.3 EPN2 "EHB21, KIAA1065" ENSG00000072134 "Epsin 2" O95208 17 19215615-19336715 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Oligodendrocyte precursor cells: 868.6;Oligodendrocytes: 258.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.9;eosinophil: 29.0;neutrophil: 9.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 29.0" "Cell line enhanced" "Detected in many" "SuSa: 127.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049809, HPA053360" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA049809: AB_2680893, HPA053360: AB_2682126" "unprognostic (1.38e-2)" "unprognostic (2.54e-2)" "unprognostic (2.58e-2)" "unprognostic (2.09e-1)" "unprognostic (1.94e-1)" "unprognostic (8.12e-3)" "unprognostic (6.73e-3)" "unprognostic (1.43e-1)" "unprognostic (8.89e-2)" "unprognostic (4.58e-3)" "unprognostic (3.42e-2)" "unprognostic (1.57e-1)" "prognostic favorable (9.13e-5)" "unprognostic (1.32e-1)" "unprognostic (9.40e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (8.15e-5)" 20.5 13.9 62.1 9.7 64.9 11.5 16.7 50.4 62.8 36.3 32.7 28.3 9.6 29.5 11.5 40.3 26.6 14.6 32.5 62.6 56.2 21.3 9.3 18.6 6.5 61.6 63.6 22.5 14.6 15.3 18.1 21.6 57.5 23.6 9.5 19.1 17.9 23.4 22.4 50.1 13.3 22.5 46.6 14.3 15.9 19.7 63.6 4.7 17.8 17.0 8.4 27.0 33.8 91.6 31.3 30.4 43.9 19.2 22.8 36.3 34.5 29.4 18.9 17.9 15.3 20.2 9.2 4.9 28.2 29.5 16.8 29.0 19.8 22.1 21.9 23.6 21.2 3.2 20.3 9.2 23.7 1.4 13.1 20.5 19.5 28.3 22.7 23.2 38.8 6.6 8.6 3.9 15.8 22.5 1.3 2.1 11.1 41.3 19.8 7.1 18.8 8.1 21.0 8.6 13.0 28.8 20.9 13.9 14.7 127.9 21.0 4.0 35.6 19.7 22.3 30.9 12.9 6.7 4.3 3.9 54.0 0.5 31.1 10.9 1.3 29.0 1.6 0.8 1.2 3.0 1.1 1.3 0.5 3.4 1.3 1.2 9.0 0.7 1.0 0.6 1.0 0.7 62.1 64.9 50.4 62.8 62.6 56.2 61.6 63.6 57.5 46.6 63.6 91.6 60.0 54.5 29.3 74.4 13.7 24.1 36.6 21.2 43.9 68.3 32.8 33.4 44.5 25.8 25.0 38.6 47.9 27.6 3.3 7.2 27.4 22.5 36.8 69.2 35.0 42.5 6.0 13.5 51.3 8.4 39.8 36.1 15.8 40.6 14.0 37.3 15.0 10.4 8.4 35.3 45.0 16.8 10.2 5.1 6.2 72.7 46.6 5.9 5.4 54.4 1.6 38.3 2.1 868.6 258.3 23.3 14.9 39.5 14.4 32.0 7.0 14.2 43.2 82.3 26.3 50.5 63.7 45.8 38.3 63.9 48.9 21.9 7.4 35.0 7.8 40.1 EPN3 "FLJ20778, MGC129899" ENSG00000049283 "Epsin 3" Q9H201 17 50532682-50543750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;stomach 1: 37.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.9;Distal enterocytes: 27.6;Gastric mucus-secreting cells: 44.9;Intestinal goblet cells: 24.9;Squamous epithelial cells: 30.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 28.6;HBEC3-KT: 40.3;MCF7: 66.4;OE19: 62.8;RT4: 50.2;SK-BR-3: 25.8;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055546, HPA063224" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Nucleoplasm "HPA055546: AB_2682844, HPA063224: AB_2684964" "unprognostic (1.91e-2)" "unprognostic (1.99e-2)" "unprognostic (2.41e-1)" "unprognostic (2.91e-2)" "unprognostic (1.25e-3)" "unprognostic (2.06e-1)" "unprognostic (5.70e-3)" "unprognostic (7.62e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (6.66e-3)" "unprognostic (1.00e-2)" "prognostic favorable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (4.90e-1)" "unprognostic (3.52e-3)" 0.2 8.9 2.3 0.8 1.3 0.6 2.3 6.4 6.0 6.5 1.2 7.1 6.8 0.4 3.2 35.9 7.5 5.9 7.1 0.7 2.1 6.0 0.1 0.3 0.0 11.5 5.4 13.5 23.0 21.2 0.8 4.2 13.6 9.9 4.4 0.2 11.1 5.6 0.1 30.5 3.2 0.1 0.5 0.0 37.3 2.8 13.4 3.2 1.1 0.0 3.7 5.5 12.9 1.8 20.5 0.3 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 0.0 14.7 12.1 0.0 0.2 0.0 0.1 28.6 0.0 40.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.2 0.1 21.8 0.1 3.0 0.0 0.0 0.1 0.0 0.0 0.0 66.4 0.3 0.0 0.0 62.8 0.4 0.0 0.0 0.1 0.2 50.2 0.4 0.0 0.0 25.8 0.0 0.4 57.4 0.2 1.5 0.3 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.3 6.4 6.0 0.7 2.1 11.5 5.4 13.6 0.5 13.4 1.8 0.2 0.0 0.0 0.0 0.4 2.3 4.4 4.1 10.8 2.9 6.5 3.4 5.4 8.6 8.3 18.4 0.0 77.9 0.0 27.6 5.9 9.2 1.0 3.8 0.6 0.4 3.6 0.0 1.0 11.5 7.4 0.8 44.9 5.5 0.0 3.1 0.0 0.0 5.9 0.0 1.7 24.9 2.0 0.0 0.0 2.1 2.8 0.5 0.0 1.0 0.6 0.6 0.0 0.0 0.0 3.4 10.3 0.0 1.3 4.9 2.1 0.3 4.3 0.9 0.0 0.0 0.8 0.0 0.5 30.0 5.5 10.7 0.2 12.4 19.3 7.8 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 EPPK1 EPIPL1 ENSG00000261150 "Epiplakin 1" P58107 8 143857324-143878467 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 16.1" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 137.1;Suprabasal keratinocytes: 274.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.3;EFO-21: 13.3;HaCaT: 13.8;HeLa: 26.8;MCF7: 20.2;SK-BR-3: 9.3" "Not detected" "Not detected" "HPA066808, HPA067357, HPA069333" Approved Enhanced "Intermediate filaments" NA NA 1200000 "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "HPA066808: AB_2685726, HPA067357: AB_2685826, HPA069333: AB_2686123" "unprognostic (1.42e-1)" "unprognostic (9.30e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (5.52e-5)" "unprognostic (2.85e-2)" "unprognostic (5.86e-3)" "unprognostic (4.90e-2)" "unprognostic (8.73e-2)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.35e-1)" "unprognostic (1.97e-3)" "unprognostic (5.94e-3)" "unprognostic (4.35e-1)" "unprognostic (3.68e-3)" "unprognostic (5.08e-3)" 0.2 0.0 0.4 0.3 0.4 0.1 0.9 3.9 0.5 0.5 1.3 3.3 2.1 2.4 0.3 1.7 2.0 0.2 0.1 0.8 0.6 1.2 0.3 0.9 0.1 2.5 2.7 0.0 0.7 0.2 0.2 0.2 1.7 1.4 0.6 0.0 2.2 1.4 0.2 16.1 2.7 0.9 1.6 1.2 2.1 1.8 0.7 0.1 0.2 0.0 0.2 1.8 0.9 0.4 7.9 0.1 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 7.4 0.5 0.0 13.3 0.0 0.0 13.8 1.4 0.1 0.0 0.0 3.4 0.0 26.8 4.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 20.2 0.0 0.0 1.4 1.8 0.0 0.0 0.1 0.0 0.0 4.9 2.3 0.0 2.2 9.3 0.0 1.2 7.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 3.9 0.5 0.8 0.6 2.5 2.7 1.7 1.6 0.7 0.4 0.7 19.2 9.2 1.0 1.1 137.1 20.3 8.2 8.0 0.6 32.7 25.0 27.9 11.5 4.4 14.7 0.0 2.5 0.0 48.1 0.0 11.3 0.5 12.6 0.5 3.2 6.0 0.0 0.3 14.7 0.3 2.4 12.2 10.1 0.0 0.6 0.7 4.4 0.3 0.0 0.0 14.5 12.2 0.0 8.2 0.3 0.0 0.4 16.0 0.0 0.0 0.6 0.0 0.0 0.1 31.9 21.7 0.0 0.2 8.6 28.2 7.0 24.2 0.2 0.0 0.0 5.2 1.5 1.0 10.6 274.3 6.2 1.2 0.1 28.4 31.5 EPS15L1 eps15R ENSG00000127527 "Epidermal growth factor receptor pathway substrate 15 like 1" Q9UBC2 19 16355239-16472085 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019237, HPA055309" Approved Approved Vesicles NA NA 110000 "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA019237: AB_1848223, HPA055309: AB_2682780" "unprognostic (3.06e-2)" "unprognostic (3.33e-3)" "unprognostic (2.19e-1)" "unprognostic (6.45e-3)" "unprognostic (1.35e-1)" "unprognostic (8.64e-2)" "unprognostic (2.58e-3)" "unprognostic (5.12e-2)" "unprognostic (1.07e-3)" "unprognostic (7.54e-2)" "unprognostic (5.21e-2)" "unprognostic (1.81e-2)" "prognostic favorable (8.10e-5)" "unprognostic (2.47e-1)" "unprognostic (9.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.32e-1)" 15.3 17.6 33.4 11.8 32.4 23.6 14.2 39.6 40.5 22.4 21.5 17.0 8.3 18.1 5.9 25.2 18.7 9.6 42.4 35.6 29.1 20.5 17.9 14.6 13.9 29.3 33.4 19.1 15.5 18.2 22.6 13.9 30.8 19.5 9.2 14.0 14.9 12.9 67.6 23.3 14.3 14.1 23.5 19.8 16.8 22.9 41.0 11.8 17.5 25.7 13.0 17.6 19.7 27.6 27.3 12.8 25.8 20.4 27.4 21.1 40.3 17.8 14.9 28.8 25.1 15.3 18.2 29.2 30.4 26.1 22.8 26.6 36.3 20.8 25.1 15.8 36.8 24.7 17.4 29.8 27.7 22.8 26.7 17.6 21.1 31.9 22.3 28.6 23.6 24.5 20.1 31.2 24.5 53.9 25.4 32.5 17.7 36.4 41.7 32.2 12.5 24.3 19.8 27.9 23.3 15.3 18.6 17.5 17.7 19.2 58.3 21.3 24.5 18.2 12.2 57.3 31.4 8.8 19.4 27.7 20.2 31.9 24.5 53.5 11.9 35.9 11.1 12.0 10.5 20.8 9.8 12.0 9.2 19.3 10.1 7.8 56.2 19.1 14.4 8.6 10.7 9.0 33.4 32.4 39.6 40.5 35.6 29.1 29.3 33.4 30.8 23.5 41.0 27.6 10.8 9.6 9.8 62.3 22.1 16.6 14.0 12.0 12.0 30.7 9.5 8.1 20.4 7.2 10.9 9.2 50.1 21.7 30.8 11.7 9.8 11.0 74.9 10.7 13.0 11.8 11.3 13.9 49.7 5.7 19.7 16.0 16.3 12.1 12.0 22.3 11.0 8.2 20.0 11.8 63.4 10.7 24.4 10.6 14.8 15.1 18.6 13.8 3.6 30.9 13.0 9.9 34.0 36.2 35.6 9.3 9.1 20.3 18.7 15.0 9.0 12.9 14.7 25.9 19.7 20.3 13.9 18.5 16.7 22.3 24.4 10.9 15.8 18.7 9.8 22.2 EPS8 ENSG00000151491 "Epidermal growth factor receptor pathway substrate 8" Q12929 12 15620134-15882329 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 317.0;Sertoli cells: 401.0;Smooth muscle cells: 313.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 22.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 253.0;HHSteC: 218.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003897 Approved Approved "Golgi apparatus" NA NA 17000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA003897: AB_1848224" "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-2)" "unprognostic (5.43e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "unprognostic (5.81e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (3.33e-7)" "unprognostic (2.68e-1)" "prognostic favorable (1.45e-7)" "unprognostic (7.47e-3)" "unprognostic (7.20e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.79e-2)" 62.3 13.0 12.9 16.1 17.4 0.6 33.7 15.3 14.0 53.9 14.1 49.7 37.6 46.2 47.1 20.5 20.1 56.0 26.4 11.1 17.2 55.8 37.8 29.0 9.4 18.5 20.1 49.2 15.1 21.6 3.5 53.1 19.7 16.4 53.7 39.8 13.4 39.8 13.8 11.9 42.7 53.7 15.5 11.9 32.0 15.6 16.1 4.8 22.8 24.3 5.2 51.7 21.4 20.8 65.0 38.8 37.7 1.4 253.0 177.6 53.1 73.6 59.8 34.5 46.1 33.3 97.3 0.0 2.4 140.4 114.4 16.4 11.3 9.5 52.4 0.2 12.6 5.7 11.2 34.7 218.1 4.4 0.2 159.8 42.8 91.7 115.7 44.6 17.7 0.2 0.1 0.2 169.0 17.5 0.2 2.8 5.2 50.3 30.8 0.0 109.5 0.8 97.7 92.5 3.1 4.9 21.4 12.4 91.5 6.2 34.2 4.3 28.7 54.7 14.3 32.4 30.7 3.6 0.4 0.1 32.1 10.7 160.0 0.0 2.7 0.2 0.2 10.8 0.1 1.3 0.9 0.4 5.5 0.3 1.1 0.5 4.4 1.0 22.2 0.4 0.1 1.7 12.9 17.4 15.3 14.0 11.1 17.2 18.5 20.1 19.7 15.5 16.1 20.8 121.4 12.8 175.9 91.1 11.6 17.0 39.6 32.0 13.6 9.7 28.7 42.8 27.6 87.2 58.3 23.9 66.7 33.0 15.2 317.0 60.7 69.4 67.6 87.4 72.0 61.4 38.3 0.4 2.2 68.9 7.3 73.4 81.1 152.2 6.3 139.4 36.0 36.0 65.8 6.7 31.1 54.5 67.1 54.1 35.6 49.4 134.8 46.2 35.6 148.0 8.6 15.4 0.0 121.2 96.9 97.0 217.8 43.6 5.2 26.9 69.0 114.6 104.8 153.7 401.0 18.1 313.1 10.9 4.2 22.8 13.1 21.1 11.8 40.0 80.0 97.6 EPS8L1 "DRC3, FLJ20258, MGC23164, MGC4642" ENSG00000131037 "EPS8 like 1" Q8TE68 19 55072020-55087923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 124.3;skin 1: 59.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 104.1;Gastric mucus-secreting cells: 108.1;Paneth cells: 110.2;Syncytiotrophoblasts: 428.0;Urothelial cells: 189.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 17.6;BEWO: 58.8;SK-BR-3: 19.6;T-47d: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041851, HPA043545" Uncertain Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "HPA041851: AB_2677706, HPA043545: AB_2678544" "unprognostic (1.91e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (7.18e-2)" "unprognostic (9.33e-2)" "unprognostic (2.54e-2)" "unprognostic (4.61e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.43e-2)" "unprognostic (5.84e-3)" "unprognostic (2.65e-2)" "unprognostic (3.85e-3)" "unprognostic (5.04e-3)" "unprognostic (3.02e-1)" "unprognostic (5.41e-3)" "unprognostic (2.63e-1)" 4.5 0.2 0.0 0.9 0.1 0.1 4.0 0.0 0.1 24.0 0.0 3.5 2.3 1.5 0.0 124.3 14.8 0.9 0.6 0.1 0.0 25.1 0.7 3.9 0.0 0.1 0.1 0.5 5.6 2.1 2.1 5.4 0.1 9.2 0.6 0.0 20.4 2.5 0.5 59.7 2.0 0.0 0.0 0.6 27.0 0.6 0.2 0.1 17.4 0.0 1.6 2.7 37.1 0.2 17.6 0.7 0.6 0.4 0.0 0.0 58.8 1.5 0.1 0.0 0.1 7.6 13.7 0.3 3.4 0.0 0.1 9.7 0.4 2.1 0.0 0.3 1.6 1.3 0.6 0.5 0.2 2.6 10.8 0.0 3.6 0.0 0.0 0.0 0.0 1.2 6.2 0.1 0.0 8.0 0.9 2.6 0.8 12.7 0.0 0.1 0.0 5.4 2.7 3.6 0.2 3.8 1.0 19.6 0.8 0.6 28.9 3.2 1.3 0.0 0.7 0.0 0.0 2.4 3.1 1.6 3.3 0.9 2.0 1.1 0.2 2.3 0.3 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.4 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 4.0 9.6 6.1 0.3 0.8 2.0 28.4 39.5 8.6 0.0 16.3 15.1 2.6 8.6 92.2 31.3 0.0 55.1 4.0 104.1 13.7 20.4 1.6 29.1 6.3 10.7 3.0 0.0 0.1 10.2 26.8 4.7 108.1 41.7 10.2 5.4 10.0 0.1 8.9 0.0 0.1 39.0 24.4 1.9 3.4 4.5 1.2 2.6 21.4 0.0 5.2 0.2 6.2 0.0 0.1 94.5 110.2 0.7 1.0 48.7 12.7 1.1 53.6 0.6 26.3 0.5 21.6 1.6 3.6 6.6 4.0 428.0 2.8 0.3 22.1 189.4 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;fallopian tube: 11.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2020.2;Inhibitory neurons: 6091.7;Oligodendrocyte precursor cells: 2369.0;Oligodendrocytes: 1049.9" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.9;EFO-21: 5.1;HEK 293: 3.8;RPTEC TERT1: 5.6;SCLC-21H: 3.1;T-47d: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 220000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 0.3 0.4 10.0 0.0 13.3 0.0 5.6 10.5 11.5 2.9 0.0 0.1 0.0 0.2 0.0 0.1 11.2 0.0 3.0 9.9 12.7 5.1 0.0 0.8 0.0 4.9 16.9 0.1 0.6 3.1 2.4 0.1 7.6 0.3 0.0 2.0 4.7 1.2 1.5 0.3 0.0 0.0 4.3 0.0 0.4 3.3 8.0 0.0 1.6 1.7 0.0 0.1 0.1 6.1 0.0 0.0 6.9 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 5.1 0.7 0.0 0.3 0.2 0.0 0.0 0.1 3.8 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 5.6 0.3 3.1 0.2 0.0 0.1 0.1 0.1 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.3 10.5 11.5 9.9 12.7 4.9 16.9 7.6 4.3 8.0 6.1 0.4 0.0 12.6 2020.2 0.0 0.6 0.9 1.1 0.6 15.9 45.6 17.0 27.2 0.0 10.2 12.9 0.0 0.0 0.2 0.0 5.9 0.5 6.7 25.4 1.0 1.0 0.0 0.0 62.0 0.5 0.2 1.8 0.0 25.8 0.0 5.4 0.0 0.0 0.1 0.0 6091.7 0.0 2.0 0.0 0.3 2.2 1.8 0.3 3.6 96.5 0.0 9.1 0.0 2369.0 1049.9 0.0 0.0 0.4 0.0 1.6 0.0 0.2 28.1 1.9 6.6 4.1 3.0 1.8 2.6 0.2 1.3 0.0 0.2 0.0 0.0 1.2 ERCC6L "FLJ20105, PICH, RAD26L" ENSG00000186871 "ERCC excision repair 6 like, spindle assembly checkpoint helicase" Q2NKX8 X 72204657-72239027 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.2;lymphoid tissue: 3.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.4;Granulosa cells: 2.5;Spermatocytes: 2.1;Spermatogonia: 2.4;Squamous epithelial cells: 2.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.7" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.7" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA050492 Approved Uncertain Nucleoplasm,Centrosome,Cytosol No Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Nucleoplasm, Cytosol" "HPA050492: AB_2681145" "prognostic unfavorable (1.80e-4)" "unprognostic (2.93e-1)" "unprognostic (1.95e-2)" "unprognostic (5.76e-3)" "unprognostic (2.43e-1)" "unprognostic (2.36e-1)" "unprognostic (9.23e-6)" "unprognostic (8.63e-3)" "unprognostic (1.57e-2)" "unprognostic (1.99e-2)" "unprognostic (3.68e-5)" "unprognostic (4.61e-2)" "unprognostic (0.00e+0)" "unprognostic (2.97e-3)" "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (6.41e-2)" 0.1 0.1 0.1 1.3 0.2 3.2 0.4 0.8 0.2 0.4 0.1 0.9 0.7 0.2 0.2 1.1 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.1 2.3 0.1 0.0 0.3 0.1 0.0 0.1 0.5 0.1 0.1 1.1 0.5 0.3 0.0 0.1 0.6 0.6 0.3 0.0 0.5 0.7 0.8 0.2 3.6 0.1 0.0 2.7 0.2 0.4 0.6 19.0 16.3 14.6 9.3 1.0 1.7 8.0 19.8 9.1 17.0 17.7 13.3 11.6 30.5 7.3 7.2 23.0 15.2 27.8 14.8 30.1 17.5 20.2 10.5 5.5 7.9 0.0 20.7 14.2 0.2 0.9 23.7 4.4 2.8 9.6 15.1 14.1 7.3 17.6 14.8 19.8 12.1 26.6 18.3 24.8 16.4 26.2 5.4 4.4 11.5 12.0 8.6 14.7 9.8 3.6 11.8 7.5 4.6 6.0 11.4 18.3 21.8 13.1 5.7 9.4 25.9 8.1 14.1 11.7 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.4 0.1 1.7 0.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.9 0.3 0.2 0.5 0.0 0.0 0.3 0.6 0.5 1.5 0.2 0.0 0.0 1.1 0.9 0.6 0.0 0.0 0.3 0.9 0.8 0.3 0.0 3.4 0.9 0.0 1.7 0.5 0.0 0.5 0.0 2.5 0.0 0.0 1.0 0.0 0.7 0.4 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.4 2.1 2.4 2.4 0.1 0.4 0.3 0.2 0.9 0.1 EREG ER ENSG00000124882 Epiregulin O14944 4 74365145-74388749 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 129.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 179.1;Kupffer cells: 133.9;Langerhans cells: 171.1;Macrophages: 570.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 270.0;CAPAN-2: 76.7;hTEC/SVTERT24-B: 83.7;U-2197: 181.4;U-87 MG: 307.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054373 Approved Vesicles "Secreted to blood" NA NA 46000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" Vesicles "HPA054373: " "unprognostic (1.26e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (4.56e-3)" "unprognostic (3.94e-2)" "unprognostic (2.24e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (6.57e-5)" "unprognostic (2.94e-1)" "unprognostic (1.70e-6)" "unprognostic (2.42e-2)" "unprognostic (1.13e-2)" "unprognostic (6.59e-3)" "unprognostic (3.16e-3)" 4.5 0.0 0.3 10.3 0.3 129.0 2.5 0.2 0.5 1.9 0.2 2.0 0.2 0.2 0.2 12.6 0.8 5.7 0.7 0.3 0.1 0.1 0.2 2.7 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.6 0.4 0.1 3.4 0.1 1.3 0.0 0.2 9.3 1.6 3.0 0.0 0.5 0.2 0.1 0.6 0.1 0.1 0.0 1.0 4.9 4.0 0.3 1.4 41.1 0.0 0.0 3.8 6.6 0.1 9.2 270.0 2.6 1.6 32.5 76.7 0.0 44.1 0.0 20.1 2.4 0.0 59.3 2.7 0.0 0.0 1.2 1.6 1.2 1.1 0.1 0.1 3.9 20.2 83.7 43.5 0.0 0.0 0.0 0.1 0.5 0.2 0.4 0.1 0.1 0.1 0.2 0.6 0.1 0.0 0.1 0.6 1.6 0.0 0.0 27.0 0.2 0.0 0.0 0.1 0.0 0.0 1.6 0.6 181.4 0.0 0.0 0.0 0.2 307.0 0.0 0.2 0.4 0.2 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.5 0.3 0.1 0.2 0.1 0.4 0.0 0.6 0.3 4.9 6.4 7.2 0.0 5.7 5.4 5.6 179.1 4.0 0.0 24.4 2.3 18.2 5.7 82.4 0.0 0.0 0.4 2.2 56.3 0.0 1.8 3.7 2.4 0.7 2.5 3.6 17.0 0.1 0.2 0.7 4.4 0.5 3.9 7.0 0.1 0.4 1.9 26.8 0.0 1.8 38.2 16.2 133.9 171.1 1.0 0.3 570.7 7.2 0.0 23.2 0.0 0.0 0.0 0.0 0.8 27.1 0.0 11.7 2.5 32.4 0.2 41.9 0.0 0.0 2.5 3.1 0.5 0.3 3.8 9.2 0.7 3.3 0.2 33.1 7.4 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ERG28 "C14orf1, NET51" ENSG00000133935 "Ergosterol biosynthesis 28 homolog" Q9UKR5 14 75649791-75660876 "Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 152.0;Ductal cells: 95.4;Exocrine glandular cells: 110.3;Extravillous trophoblasts: 154.2;Syncytiotrophoblasts: 116.3;Theca cells: 121.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043172 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" "HPA043172: AB_10793942" "unprognostic (2.68e-3)" "unprognostic (2.11e-2)" "unprognostic (4.55e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-1)" "unprognostic (1.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.66e-2)" "unprognostic (4.64e-1)" "unprognostic (2.66e-2)" "unprognostic (2.47e-1)" "unprognostic (3.01e-2)" "prognostic favorable (4.30e-5)" "unprognostic (1.28e-1)" "unprognostic (2.77e-1)" "unprognostic (9.58e-3)" "unprognostic (2.20e-1)" 9.8 27.7 24.0 9.1 23.3 13.2 17.3 24.6 26.2 16.9 25.1 16.5 21.6 14.9 40.6 34.6 16.9 11.9 13.6 24.6 25.0 18.5 70.2 22.6 11.5 26.2 25.2 20.0 16.1 29.7 17.4 14.9 25.4 21.2 15.5 19.4 19.9 13.8 10.3 24.8 14.5 14.6 25.4 8.3 13.6 47.1 25.8 10.2 21.5 11.3 14.6 12.5 20.1 27.5 39.2 21.6 42.7 33.5 28.6 53.1 26.6 15.6 48.2 29.9 51.0 33.8 91.4 16.6 22.3 19.6 59.7 42.4 38.5 67.0 34.0 31.2 25.4 17.8 20.5 48.4 41.4 19.7 25.5 66.5 56.7 42.9 23.8 24.0 35.3 44.7 16.0 39.3 20.9 77.7 30.2 21.8 41.8 62.5 34.7 23.9 28.7 33.0 99.8 50.5 36.6 20.1 39.2 33.5 24.1 37.8 56.1 28.3 25.1 16.1 32.0 15.8 15.8 25.3 32.5 36.1 25.7 28.5 27.7 33.5 12.3 20.0 40.0 12.7 39.5 39.4 43.1 41.8 29.8 34.5 39.1 38.5 6.6 31.8 13.2 38.4 42.7 31.9 24.0 23.3 24.6 26.2 24.6 25.0 26.2 25.2 25.4 25.4 25.8 27.5 18.8 22.4 57.5 0.0 9.3 0.0 0.0 0.0 0.0 0.0 74.7 57.7 0.0 0.0 11.2 60.7 0.0 152.0 23.6 0.0 49.0 95.4 0.0 43.4 11.5 18.0 0.0 0.0 0.0 110.3 154.2 21.4 0.0 30.3 5.1 63.2 0.0 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 37.7 0.0 0.0 0.0 0.0 76.9 0.0 0.0 3.5 0.0 0.0 47.1 18.2 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 116.3 12.4 121.2 0.0 0.0 ERMP1 "FLJ23309, FXNA, KIAA1815" ENSG00000099219 "Endoplasmic reticulum metallopeptidase 1" Q7Z2K6 9 5765076-5833117 "Enzymes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 50.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 73.5;Granulosa cells: 53.4;Oligodendrocytes: 88.8;Urothelial cells: 66.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 76.8;RT4: 154.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055582 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA055582: " "unprognostic (1.93e-2)" "unprognostic (3.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.93e-2)" "unprognostic (2.97e-1)" "unprognostic (8.59e-2)" "unprognostic (4.30e-3)" "unprognostic (2.81e-1)" "unprognostic (5.46e-2)" "unprognostic (4.83e-3)" "unprognostic (3.14e-2)" "unprognostic (2.88e-2)" "prognostic favorable (5.83e-10)" "unprognostic (1.41e-1)" "unprognostic (4.00e-1)" "unprognostic (5.77e-2)" "unprognostic (1.36e-1)" 3.9 7.9 4.2 3.7 10.4 2.0 6.3 10.9 3.7 10.8 14.4 11.3 4.4 5.6 2.6 14.9 6.4 11.3 10.0 2.9 6.1 24.9 4.6 6.3 3.5 10.1 10.3 4.5 3.9 50.1 1.5 7.8 8.8 6.0 11.4 2.2 19.1 4.1 7.6 9.3 6.5 3.8 6.5 3.1 13.3 4.7 8.9 4.6 26.6 9.9 6.4 17.1 4.8 13.1 45.1 43.1 1.8 5.2 22.6 20.7 22.6 5.1 11.1 2.3 1.9 10.4 27.2 10.7 19.2 8.4 25.9 32.2 9.6 29.4 3.3 55.6 7.6 56.2 20.0 20.4 4.8 16.0 21.3 10.5 12.9 2.1 13.3 28.6 30.1 4.6 6.9 9.9 2.8 20.7 0.6 6.2 6.6 28.0 8.4 1.7 5.3 14.1 76.8 154.6 9.9 3.3 7.1 52.2 8.1 24.5 33.7 20.5 18.0 1.5 5.0 3.4 16.1 8.9 13.6 5.5 6.7 13.0 4.1 0.2 0.1 0.3 0.4 0.1 0.6 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.0 0.1 0.1 0.1 4.2 10.4 10.9 3.7 2.9 6.1 10.1 10.3 8.8 6.5 8.9 13.1 3.4 6.4 1.1 24.8 2.2 2.9 18.3 13.3 2.8 4.0 11.1 5.8 13.7 12.8 22.8 73.5 10.4 6.8 5.2 32.1 0.0 4.6 22.3 11.4 10.9 6.3 11.4 6.3 21.0 3.0 7.1 4.6 13.7 13.8 8.9 53.4 2.9 6.1 5.7 3.3 32.8 8.9 10.2 1.6 2.2 41.8 3.1 4.5 1.8 24.4 2.1 3.0 8.2 22.1 88.8 3.5 22.5 4.9 4.1 7.0 9.2 3.3 16.6 2.9 6.6 5.8 4.3 8.8 4.6 17.5 4.5 4.1 5.9 39.8 15.7 66.9 ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690310-23713226 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 19.5;gallbladder: 17.0;intestine: 28.9;salivary gland: 22.9;stomach 1: 51.9" "Cell type enhanced" "Detected in some" "Club cells: 38.4;Distal enterocytes: 80.2;Gastric mucus-secreting cells: 193.7;Intestinal goblet cells: 143.9;Paneth cells: 37.2;Undifferentiated cells: 70.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.0;pancreatic cancer: 19.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 43.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA076875 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum, Cytosol" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" 0.1 0.4 0.1 3.0 0.1 0.0 0.1 0.6 0.4 19.5 0.2 28.9 12.9 0.0 0.0 0.9 0.4 17.0 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 0.2 3.5 23.0 0.0 22.9 0.1 0.0 0.2 12.4 0.9 0.0 0.0 51.9 0.1 0.1 0.0 0.0 0.0 0.0 4.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.4 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.4 0.0 0.0 1.1 0.0 0.8 0.0 1.5 6.8 0.0 0.0 0.0 0.0 0.5 20.0 38.4 0.0 0.0 0.5 0.0 80.2 0.0 2.3 0.1 0.5 0.2 0.1 10.8 0.0 0.2 1.9 0.0 0.1 193.7 1.6 4.5 0.1 0.0 0.0 0.1 0.0 0.1 143.9 6.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 33.1 37.2 0.0 0.5 1.3 6.1 0.1 16.9 0.0 0.0 1.7 1.6 0.0 0.2 0.0 0.0 0.1 0.4 0.0 70.9 11.1 ERP29 "C12orf8, ERp28, ERp31, PDI-DB, PDIA9" ENSG00000089248 "Endoplasmic reticulum protein 29" P30040 12 112013348-112023449 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039363, HPA039456" Enhanced Uncertain Nucleoplasm,Microtubules "Intracellular and membrane" NA NA 900000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Microtubules Nucleoplasm "HPA039363: AB_10673422, HPA039456: AB_10672963" "unprognostic (2.70e-2)" "unprognostic (1.16e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.43e-5)" "unprognostic (1.13e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" "unprognostic (5.10e-3)" "unprognostic (2.58e-1)" "unprognostic (3.21e-1)" "unprognostic (2.74e-3)" "unprognostic (3.34e-1)" "unprognostic (1.76e-1)" "unprognostic (6.26e-2)" 62.7 100.9 56.9 77.9 58.0 202.3 84.0 65.1 62.0 78.4 91.1 94.5 100.7 60.5 109.8 91.5 74.8 64.1 59.0 56.0 68.7 93.0 179.9 78.8 123.8 61.1 62.6 78.9 174.6 123.6 99.1 73.0 64.2 93.4 91.3 68.3 122.7 87.4 34.3 113.3 96.1 47.1 57.8 118.3 131.4 57.6 60.8 107.6 90.4 34.3 111.2 75.9 71.0 61.6 145.4 137.2 98.8 194.2 367.4 143.7 211.3 139.2 163.7 108.5 139.3 215.2 164.4 152.7 106.4 244.5 117.8 175.4 187.8 181.2 89.3 133.7 104.2 174.3 150.1 239.2 246.8 432.1 164.0 207.5 227.6 178.4 201.6 287.4 156.1 157.9 203.2 277.3 84.7 166.6 140.9 765.7 161.5 513.1 102.5 114.2 120.9 501.2 229.8 213.5 88.6 119.8 173.6 140.1 426.1 187.4 177.1 575.7 116.5 92.6 142.7 88.8 103.3 303.4 379.8 128.0 157.8 268.5 73.2 96.2 241.4 346.2 131.6 178.8 140.4 259.1 170.7 164.1 229.7 264.1 186.5 154.9 47.5 86.5 170.9 455.8 179.6 307.4 56.9 58.0 65.1 62.0 56.0 68.7 61.1 62.6 64.2 57.8 60.8 61.6 102.6 83.3 183.4 13.7 324.8 141.4 205.5 249.3 132.6 125.3 207.8 199.9 91.6 198.8 178.0 185.8 110.5 497.7 396.6 210.1 93.9 239.5 7.7 142.1 84.9 114.9 197.9 134.4 14.4 211.8 405.3 118.3 131.5 149.9 88.8 164.4 146.3 346.6 373.1 80.8 20.6 280.6 343.8 306.9 192.6 16.6 128.9 230.4 168.9 12.2 269.0 152.8 160.6 11.6 22.8 128.7 288.0 106.8 350.1 195.4 355.5 274.6 187.0 164.9 52.6 79.2 112.2 100.3 195.3 143.1 161.0 441.6 221.7 252.4 285.2 219.8 ERV3-1 "envR, ERV-R, ERV3, H-PLK, HERV-R" ENSG00000213462 "Endogenous retrovirus group 3 member 1, envelope" Q14264 7 64990356-65006743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.7" "HPA017209, HPA046508" Enhanced Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017209: AB_2732419, HPA046508: AB_2732525" "unprognostic (2.74e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-1)" "unprognostic (1.27e-2)" "unprognostic (4.48e-1)" "unprognostic (2.03e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" "unprognostic (4.05e-3)" "unprognostic (3.55e-1)" "unprognostic (1.57e-2)" "unprognostic (4.45e-2)" "unprognostic (4.27e-3)" "unprognostic (2.11e-1)" "unprognostic (2.19e-1)" "unprognostic (9.39e-2)" "unprognostic (1.88e-2)" 22.8 33.0 4.8 8.5 4.5 9.3 15.0 4.1 6.4 10.0 5.1 5.7 3.5 10.0 32.5 15.2 8.0 16.4 6.2 4.7 6.2 4.8 3.2 9.7 5.7 6.2 7.9 7.3 5.3 15.3 8.2 13.4 5.4 7.3 5.7 13.5 12.1 7.5 3.6 12.3 4.5 7.6 4.8 6.9 6.3 8.7 5.9 6.6 7.6 1.8 7.4 6.2 11.5 5.1 3.3 1.0 17.4 27.7 11.3 4.7 12.4 5.7 6.3 2.0 4.6 1.2 20.5 5.5 5.3 2.2 4.0 3.9 2.6 1.5 3.2 4.1 1.5 2.8 1.6 11.5 1.0 6.7 3.7 5.1 1.6 1.8 0.6 10.4 11.6 6.0 12.7 10.3 8.1 8.1 4.9 5.0 5.1 10.8 1.2 11.4 0.7 3.7 3.5 6.8 3.6 16.8 6.2 1.9 0.7 18.9 4.7 16.4 9.2 6.7 1.0 5.1 2.8 3.2 7.8 1.6 5.7 20.8 4.1 0.0 1.0 2.4 0.6 1.8 0.5 0.4 0.1 0.4 0.8 0.5 0.3 0.4 7.0 1.1 0.5 0.4 1.2 0.6 4.8 4.5 4.1 6.4 4.7 6.2 6.2 7.9 5.4 4.8 5.9 5.1 7.1 3.2 13.1 17.9 32.5 4.2 15.6 17.0 7.4 24.8 13.7 10.4 2.1 24.3 25.5 16.5 29.2 16.5 21.6 4.4 9.8 14.4 7.3 6.2 8.6 10.9 13.8 19.4 12.2 17.9 12.7 8.3 12.8 5.9 8.2 20.4 13.6 3.6 9.7 18.5 13.0 9.1 16.2 21.8 16.5 4.8 11.5 19.8 10.6 14.0 16.7 11.3 36.0 24.1 14.0 17.6 7.8 9.8 10.0 12.5 15.4 4.9 14.0 21.4 6.6 7.6 8.7 12.2 11.8 8.6 5.7 40.2 20.5 10.7 6.7 31.1 ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 405.9;Endothelial cells: 301.0;Hepatic stellate cells: 138.1;Sertoli cells: 151.2;Smooth muscle cells: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Group enriched" "Detected in many" 10 "HEL: 218.8;HUVEC TERT2: 277.9;TIME: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" 97.5 17.7 38.4 9.0 37.7 1.9 79.4 38.8 46.9 33.3 30.1 20.0 7.0 36.2 7.8 21.8 34.2 20.0 83.0 35.2 38.7 63.6 11.5 112.5 8.7 40.9 38.9 14.4 13.6 13.2 14.8 106.9 44.0 19.8 7.8 2.5 15.6 15.6 27.1 18.2 20.9 29.4 37.3 17.3 23.4 4.3 45.4 5.4 95.9 49.8 8.3 30.8 30.2 37.8 1.2 1.6 0.4 1.2 0.0 0.3 5.1 0.1 0.1 0.0 0.1 2.7 14.1 1.2 3.2 0.0 0.2 0.0 3.7 0.0 0.0 1.8 1.3 218.8 0.1 8.0 0.6 0.4 3.6 0.0 0.0 0.0 0.0 0.2 277.9 0.1 0.2 5.9 0.5 1.8 0.0 0.0 0.6 20.8 2.1 0.0 1.0 0.9 0.0 2.4 0.2 0.8 0.1 16.1 0.0 7.5 3.3 0.8 142.0 0.4 0.4 0.5 0.0 0.2 0.2 0.2 0.1 0.5 0.4 8.2 0.6 0.0 0.1 0.3 0.0 2.1 1.5 0.1 0.4 7.5 2.2 0.8 6.5 0.0 0.0 0.4 0.4 24.8 38.4 37.7 38.8 46.9 35.2 38.7 40.9 38.9 44.0 37.3 45.4 37.8 405.9 38.5 56.0 2.0 4.5 15.2 0.5 0.2 2.8 18.5 2.5 3.2 11.2 0.0 3.0 14.7 4.2 1.8 2.5 3.5 5.9 7.6 5.0 1.1 1.5 301.0 0.0 5.3 1.5 2.4 18.7 13.8 3.6 1.4 3.8 0.1 138.1 1.7 1.1 0.0 0.4 0.4 0.0 5.3 22.1 26.3 0.9 25.7 12.4 20.6 1.2 0.7 0.0 0.5 0.4 46.5 2.1 0.4 2.8 1.8 0.1 0.1 1.9 1.3 151.2 4.6 89.4 0.1 0.9 0.8 10.9 37.1 2.0 2.4 1.6 2.3 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 ESPN DFNB36 ENSG00000187017 Espin B1AK53 1 6424776-6461367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing Actin-binding "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 129.1;retina: 117.8;testis: 145.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.5;Early spermatids: 137.5;Late spermatids: 461.6;Muller glia cells: 272.5;Paneth cells: 186.3;Proximal enterocytes: 512.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 13.4;thalamus: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 48.9;Hep G2: 81.5;SK-BR-3: 160.1;T-47d: 53.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 2.6" "HPA028674, HPA060220" Enhanced Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA028674: AB_10601316, HPA060220: AB_2684224" "unprognostic (5.06e-2)" "unprognostic (1.18e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-1)" "unprognostic (2.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (2.28e-1)" "unprognostic (1.16e-1)" "unprognostic (5.71e-2)" "unprognostic (7.48e-3)" "unprognostic (5.53e-2)" "unprognostic (6.26e-3)" "unprognostic (5.51e-2)" "unprognostic (1.16e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-2)" 0.6 5.7 0.4 2.6 1.0 28.0 9.2 13.4 1.0 30.3 0.2 28.2 90.4 2.4 39.9 34.3 18.6 0.3 0.9 0.4 1.7 63.4 129.1 3.2 0.3 0.6 1.3 0.4 0.9 26.8 42.1 0.9 1.1 10.0 6.8 117.8 9.4 6.2 0.8 91.7 89.5 0.8 0.3 0.9 2.7 145.3 6.1 1.6 0.4 0.0 1.7 1.3 22.3 0.5 14.1 0.7 0.6 0.1 0.0 0.0 48.9 0.0 0.0 0.2 0.0 29.9 1.5 0.5 6.5 0.0 0.1 32.6 2.3 0.1 0.0 2.0 0.7 0.4 0.7 81.5 0.0 0.6 2.7 0.1 0.6 0.0 0.0 0.0 0.0 1.0 17.6 0.0 0.0 28.2 0.2 1.0 0.6 3.8 12.2 0.0 0.4 10.9 0.2 0.1 21.0 0.7 3.7 160.1 5.0 0.3 53.6 7.4 15.6 0.1 0.8 0.6 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 1.0 13.4 1.0 0.4 1.7 0.6 1.3 1.1 0.3 6.1 0.5 0.2 0.0 0.6 0.0 0.8 7.8 2.4 4.5 12.5 5.6 10.7 3.9 1.4 11.5 3.8 9.2 68.8 3.0 0.2 175.5 13.7 0.2 137.5 19.1 0.9 0.8 6.0 8.2 0.2 3.1 0.5 0.3 5.6 12.4 0.0 0.0 3.9 109.4 0.2 0.0 0.2 36.3 8.2 3.2 0.9 461.6 3.7 1.5 0.0 0.0 0.0 272.5 0.0 0.0 0.1 0.1 186.3 2.2 0.0 1.6 512.1 102.2 9.0 72.5 0.0 0.0 0.2 12.3 3.9 17.6 22.7 6.6 1.5 0.0 35.3 2.9 ESRP1 "FLJ20171, RBM35A" ENSG00000104413 "Epithelial splicing regulatory protein 1" Q6NXG1 8 94641074-94707466 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 107.2;Suprabasal keratinocytes: 79.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 138.3;BEWO: 101.1;CAPAN-2: 140.8;hTCEpi: 226.5;OE19: 142.6;RT4: 99.1;T-47d: 108.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023719, HPA023720, HPA067104" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" Nucleoplasm "HPA023719: AB_1856124, HPA023720: AB_1856125, HPA067104: AB_2685779" "prognostic unfavorable (9.28e-4)" "unprognostic (7.12e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.12e-1)" "unprognostic (6.99e-3)" "unprognostic (2.70e-1)" "unprognostic (2.61e-2)" "unprognostic (5.19e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (4.48e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.96e-2)" "unprognostic (1.29e-1)" 0.2 0.0 0.0 5.2 0.0 0.0 24.2 0.0 0.0 15.5 0.0 57.1 25.2 3.4 29.6 64.2 21.3 8.5 0.1 0.0 0.0 8.5 0.4 15.8 0.0 0.0 0.1 0.1 42.6 28.4 7.2 12.2 0.0 19.9 62.8 0.0 25.9 10.0 0.1 60.6 22.0 2.5 0.0 0.0 38.6 0.6 0.4 5.2 36.6 0.0 15.3 22.5 28.8 0.0 138.3 0.0 0.0 0.2 0.0 0.0 101.1 0.0 0.0 0.0 0.0 44.6 140.8 0.0 3.8 0.0 0.1 81.6 3.8 70.9 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 226.5 0.0 1.4 0.0 0.0 10.7 0.0 0.0 0.0 67.3 1.9 0.4 12.4 142.6 3.4 0.0 0.0 18.3 17.4 99.1 35.1 0.3 0.0 21.0 14.0 21.4 108.0 0.9 0.0 0.1 0.2 0.1 0.3 12.0 13.8 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 38.5 36.7 0.0 0.6 44.6 18.9 30.4 35.9 0.0 29.4 18.0 1.0 21.5 32.4 27.6 0.0 55.1 0.5 76.2 13.7 19.6 12.9 47.1 3.7 0.9 33.1 0.0 2.6 27.5 69.1 0.9 58.1 46.5 1.3 0.0 0.4 0.1 6.0 0.0 0.4 107.2 16.2 0.0 3.2 10.3 0.0 0.5 24.9 0.0 0.6 0.0 0.0 0.5 0.4 21.7 48.1 0.7 1.8 25.1 25.5 0.3 35.0 0.0 0.0 0.0 1.2 0.6 0.9 71.3 79.1 62.1 0.8 0.0 73.9 40.1 ESRRG "ERR-gamma, ERRg, NR3B3" ENSG00000196482 "Estrogen related receptor gamma" P62508 1 216503246-217137755 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.6;parathyroid gland: 46.3;retina: 36.1;stomach 1: 35.1" "Group enriched" "Detected in many" 4 "Astrocytes: 330.7;Excitatory neurons: 415.2;Inhibitory neurons: 495.5;Oligodendrocyte precursor cells: 391.6;Oligodendrocytes: 218.7;Syncytiotrophoblasts: 214.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 23.0;SH-SY5Y: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044678 Uncertain Approved Nucleoplasm No NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA044678: AB_10963215" "unprognostic (6.48e-2)" "unprognostic (1.11e-1)" "unprognostic (7.06e-2)" "unprognostic (7.32e-2)" "unprognostic (2.34e-1)" "unprognostic (5.48e-2)" "unprognostic (1.66e-1)" "unprognostic (1.13e-1)" "unprognostic (4.55e-2)" "unprognostic (2.88e-1)" "unprognostic (2.35e-1)" "unprognostic (1.79e-2)" "prognostic favorable (1.13e-11)" "unprognostic (3.04e-1)" "unprognostic (2.55e-1)" "unprognostic (3.65e-4)" "unprognostic (2.05e-1)" 0.4 6.4 1.1 0.2 3.1 0.0 3.6 16.9 12.3 1.5 7.4 0.5 5.3 0.4 0.9 1.6 2.5 0.7 10.6 4.4 2.3 29.0 0.7 0.5 0.2 45.4 4.9 0.7 5.7 46.3 1.5 10.6 49.6 3.1 0.3 36.1 16.0 0.7 5.8 0.8 5.0 0.2 1.6 1.1 35.1 1.1 3.5 0.6 5.9 10.2 0.3 0.7 0.2 6.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 0.0 0.2 0.0 0.0 23.0 3.4 2.5 8.1 42.4 0.0 0.4 0.0 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 3.1 16.9 12.3 4.4 2.3 45.4 4.9 49.6 1.6 3.5 6.1 0.2 0.0 1.8 330.7 0.2 0.3 3.8 0.6 0.6 29.5 9.5 5.2 51.2 10.0 1.8 23.9 58.4 35.4 0.0 0.0 54.8 5.0 5.1 15.9 2.0 1.3 8.3 0.0 415.2 2.4 4.7 3.0 70.3 3.5 0.0 0.5 1.1 0.6 4.8 48.8 495.5 1.7 14.2 0.3 0.4 8.1 0.3 0.5 8.8 36.5 0.0 13.3 0.0 391.6 218.7 0.4 1.3 0.7 0.1 4.9 16.3 29.0 16.0 41.3 0.0 10.3 0.4 1.6 0.3 0.8 0.3 214.9 0.3 1.1 2.6 1.7 ESYT3 "CHR3SYT, FAM62C" ENSG00000158220 "Extended synaptotagmin 3" A0FGR9 3 138434586-138481686 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;skin 1: 7.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Alveolar cells type 2: 37.7;Excitatory neurons: 9.4;Inhibitory neurons: 9.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.4;NTERA-2: 3.3;SCLC-21H: 3.5;SK-MEL-30: 1.7;SuSa: 1.4" "Region enhanced" "Detected in many" "hypothalamus: 7.3" "Low region specificity" "Detected in all" HPA039200 Approved NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" "HPA039200: AB_10805356" "unprognostic (4.48e-2)" "unprognostic (3.07e-2)" "unprognostic (1.21e-2)" "unprognostic (1.38e-4)" "unprognostic (2.23e-1)" "unprognostic (8.22e-2)" "unprognostic (3.55e-3)" "prognostic favorable (8.30e-4)" "unprognostic (3.38e-1)" "unprognostic (5.57e-2)" "unprognostic (6.19e-3)" "unprognostic (4.88e-3)" "unprognostic (3.16e-5)" "unprognostic (3.46e-1)" "unprognostic (1.12e-1)" "unprognostic (2.13e-1)" "unprognostic (6.43e-2)" 0.1 0.1 2.5 0.0 2.0 0.0 0.7 5.1 2.2 0.8 0.2 3.8 0.0 2.2 0.0 0.4 0.2 0.3 0.5 2.1 2.3 0.9 0.0 4.7 0.0 2.2 2.1 0.5 1.0 0.8 1.9 0.3 2.5 0.2 0.2 0.1 0.3 0.0 0.4 7.7 0.3 1.5 1.3 0.0 1.7 0.5 2.4 0.0 4.7 0.0 0.4 1.0 0.7 1.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.8 0.8 0.1 0.2 1.3 0.0 0.0 0.2 0.0 0.1 0.4 0.5 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.2 3.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 3.5 0.0 1.2 0.1 1.7 1.4 0.3 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.0 5.1 2.2 2.1 2.3 2.2 2.1 2.5 1.3 2.4 1.5 0.1 38.5 37.7 4.2 0.1 0.8 0.8 0.5 1.2 1.9 0.9 1.3 2.5 1.5 4.5 1.8 4.2 0.8 0.0 0.1 0.0 1.0 0.2 1.5 0.8 0.7 0.0 0.0 9.4 0.9 0.4 0.9 3.6 2.2 0.0 0.5 0.4 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.4 0.2 0.3 0.2 1.8 1.0 0.0 0.3 0.0 2.0 0.5 0.7 0.1 0.0 0.0 1.1 0.0 0.3 0.8 3.9 0.0 1.4 0.3 1.5 1.7 0.5 1.6 0.7 0.1 0.7 0.2 0.1 ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 263.1;dendritic cells: 378.9;Endothelial cells: 190.4;Hepatic stellate cells: 213.8;NK-cells: 399.6;T-cells: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 352.9;JURKAT: 362.3;U-698: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" 101.2 19.2 11.7 145.7 10.4 35.3 65.4 9.8 14.1 35.9 8.9 31.2 26.9 36.5 9.3 21.8 20.2 62.5 43.0 8.9 11.3 30.4 47.6 76.2 277.1 13.1 14.7 27.0 20.1 28.4 7.8 56.3 13.4 17.1 31.4 1.8 16.5 20.7 25.6 18.1 49.3 38.1 11.6 185.8 46.1 8.0 15.2 328.8 39.8 42.3 250.2 67.9 19.2 11.3 87.7 15.7 72.8 0.3 30.7 49.3 0.2 65.7 140.2 80.9 77.3 5.1 91.7 312.1 65.7 109.5 184.7 29.8 7.0 190.0 169.0 66.6 1.1 352.9 6.4 0.3 82.2 36.7 4.0 97.2 15.0 69.6 252.2 46.1 67.9 362.3 0.6 63.3 98.1 0.0 185.7 27.4 27.0 7.9 55.0 50.4 118.7 24.5 64.2 95.6 0.9 5.0 34.5 0.7 73.6 48.5 0.3 17.7 126.1 180.5 57.1 35.5 109.1 46.7 8.9 462.5 32.2 68.0 162.1 51.2 0.1 6.6 20.4 0.3 28.9 12.3 27.0 25.0 0.2 9.2 32.5 26.1 1.1 27.8 1.0 6.2 33.3 9.5 11.7 10.4 9.8 14.1 8.9 11.3 13.1 14.7 13.4 11.6 15.2 11.3 263.1 25.6 26.5 2.9 125.6 114.8 41.0 12.4 1.8 0.0 8.2 7.2 9.0 4.3 24.3 11.0 0.0 0.2 378.9 13.1 0.0 31.9 6.2 26.3 51.0 190.4 15.5 13.7 2.0 22.6 0.5 45.5 17.3 66.2 19.6 1.3 213.8 5.4 7.3 0.0 25.6 15.0 10.2 18.3 48.2 1.5 14.0 12.5 69.4 65.6 16.8 0.2 399.6 55.3 9.5 99.3 6.6 15.4 129.6 26.8 2.2 4.6 5.9 0.2 105.2 55.5 76.6 0.7 1.8 1.5 63.2 0.4 323.2 40.4 5.8 32.6 ETV1 ER81 ENSG00000006468 "ETS variant transcription factor 1" P50549 7 13891229-13991425 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 119.9;salivary gland: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 137.7;Astrocytes: 67.3;Cardiomyocytes: 87.7;Enteroendocrine cells: 198.1;Excitatory neurons: 66.9;Oligodendrocyte precursor cells: 135.7" "Cancer enhanced" "Detected in all" "glioma: 22.5" "Group enriched" "Detected in all" 5 "cerebellum: 119.9;thalamus: 32.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 67.8;hTERT-RPE1: 76.2;SCLC-21H: 79.3;U-87 MG: 157.2;WM-115: 78.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 200.7" "HPA068389, HPA077249" Supported Approved Nucleoplasm No No "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA068389: , HPA077249: AB_2686829" "unprognostic (2.45e-1)" "unprognostic (1.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-2)" "unprognostic (2.13e-2)" "unprognostic (1.64e-7)" "unprognostic (7.08e-3)" "unprognostic (7.21e-2)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-3)" "unprognostic (2.21e-2)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" 4.9 23.0 13.6 1.9 10.9 0.2 8.2 119.9 12.1 2.3 0.1 4.1 2.2 4.4 2.3 2.7 1.5 17.3 35.6 14.6 5.6 3.2 3.9 28.7 1.4 4.6 14.0 1.4 3.1 11.5 7.4 3.5 9.0 5.5 4.3 4.5 91.6 12.6 0.8 1.9 3.5 3.5 3.1 9.1 2.6 8.9 32.8 4.7 12.2 2.5 1.9 2.7 1.5 8.1 0.1 4.9 35.5 67.8 12.1 35.4 0.1 3.2 12.1 2.0 8.0 0.0 16.6 0.0 3.6 5.6 9.8 0.4 1.5 3.8 4.3 0.9 1.6 2.1 3.1 0.0 7.1 12.3 4.5 10.7 0.0 23.3 1.9 76.2 15.3 1.1 11.0 0.6 14.6 0.0 0.1 0.0 53.2 2.1 36.5 0.0 21.5 2.9 23.7 0.4 79.3 15.6 0.0 1.2 19.6 12.2 1.2 0.5 8.6 7.0 2.2 13.8 13.4 12.2 4.1 0.0 157.2 0.8 78.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 10.9 119.9 12.1 14.6 5.6 4.6 14.0 9.0 3.1 32.8 8.1 16.0 19.2 137.7 67.3 0.0 1.0 2.8 0.9 13.6 4.9 5.8 23.6 87.7 28.6 0.7 3.7 0.0 0.6 0.1 0.8 5.9 3.6 25.4 1.3 3.9 11.1 198.1 0.8 66.9 0.9 0.4 17.7 1.1 2.0 2.5 0.2 2.9 13.1 3.4 5.0 45.3 2.4 0.0 7.2 1.6 8.7 1.5 0.7 12.4 28.1 0.0 12.6 0.0 135.7 4.3 0.9 0.1 34.6 1.2 0.6 0.0 3.0 1.4 0.6 19.7 17.4 12.6 1.2 2.1 3.1 1.3 0.3 2.2 9.7 1.2 0.3 ETV2 ER71 ENSG00000105672 "ETS variant transcription factor 2" O00321 19 35641745-35644871 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "testis: 19.0" "Group enriched" "Detected in many" 10 "Early spermatids: 146.6;Late spermatids: 443.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 24.4" "Lineage enriched" "Detected in all" 6 "dendritic cells: 24.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.14e-1)" "unprognostic (3.24e-2)" "unprognostic (1.73e-1)" "unprognostic (5.44e-2)" "unprognostic (1.30e-1)" "unprognostic (2.53e-3)" "unprognostic (1.42e-1)" "unprognostic (2.77e-1)" "unprognostic (2.83e-1)" "unprognostic (2.69e-3)" "unprognostic (8.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.12e-1)" "unprognostic (4.20e-4)" "unprognostic (2.48e-1)" "unprognostic (1.41e-1)" "unprognostic (2.74e-1)" 1.5 2.1 0.6 0.7 0.6 0.5 1.2 2.2 1.0 1.8 0.6 1.5 2.0 0.9 0.1 3.6 1.0 0.3 0.7 0.6 0.8 1.8 2.7 1.1 0.6 0.9 0.7 1.4 3.6 1.2 1.3 0.3 0.9 1.5 0.4 0.4 2.3 0.6 0.2 3.4 1.5 0.3 0.7 1.0 1.7 19.0 0.6 0.4 1.1 0.0 0.2 1.0 2.1 0.6 1.4 1.9 1.2 1.5 1.4 2.7 0.2 0.5 0.8 1.4 2.2 0.7 0.7 0.2 2.0 1.0 0.3 0.5 0.1 1.0 0.1 2.3 2.3 2.6 1.1 1.3 2.4 0.8 3.4 2.4 2.0 0.7 1.1 0.8 0.4 0.8 0.8 1.0 0.8 1.7 1.2 0.8 0.1 2.3 0.6 1.7 3.1 2.0 2.1 1.3 1.6 1.1 1.7 0.3 3.0 0.3 1.2 3.0 0.4 4.2 2.1 2.3 1.7 1.1 2.5 0.4 2.0 0.9 4.1 0.0 2.2 1.1 3.1 3.3 3.4 2.3 3.8 3.9 2.6 1.2 2.1 2.7 0.8 1.0 3.8 24.4 3.3 1.8 0.6 0.6 2.2 1.0 0.6 0.8 0.9 0.7 0.9 0.7 0.6 0.6 2.4 0.0 1.1 0.0 2.8 5.7 3.5 8.4 12.0 5.1 9.0 12.2 1.4 4.3 2.6 5.5 0.0 1.9 7.0 12.1 7.9 1.9 146.6 1.7 2.7 2.4 7.7 1.7 0.0 5.3 2.8 3.3 2.6 3.4 1.3 1.0 4.6 19.9 2.2 0.0 0.1 9.7 2.0 2.0 5.1 443.3 9.0 2.8 1.8 0.0 2.0 3.1 1.0 0.0 0.1 1.7 4.8 2.6 8.4 3.3 28.6 20.9 1.1 2.8 0.0 6.7 2.3 6.7 2.8 11.3 12.9 1.9 3.6 3.5 7.1 6.1 ETV3 PE-1 ENSG00000117036 "ETS variant transcription factor 3" P41162 1 157121191-157138474 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 361.2;monocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004794, HPA073211" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA004794: AB_1078761, HPA073211: " "unprognostic (1.65e-1)" "unprognostic (2.37e-1)" "unprognostic (3.78e-2)" "unprognostic (4.39e-2)" "unprognostic (7.59e-2)" "unprognostic (5.23e-2)" "unprognostic (1.38e-2)" "unprognostic (3.30e-1)" "unprognostic (2.36e-2)" "unprognostic (5.37e-2)" "unprognostic (1.34e-2)" "unprognostic (8.02e-2)" "unprognostic (7.26e-3)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" "unprognostic (8.97e-2)" "unprognostic (6.65e-2)" 13.7 7.7 6.6 11.1 6.6 24.0 12.1 7.9 20.1 8.3 5.3 8.7 15.1 9.3 7.5 15.6 7.8 12.7 7.4 8.3 8.1 6.6 6.6 12.6 10.1 7.7 6.5 11.5 6.4 23.9 5.0 12.8 7.0 10.2 9.5 5.7 9.2 8.5 9.4 31.5 14.6 10.1 7.1 10.0 10.0 9.4 7.4 10.8 7.9 8.8 12.5 17.6 11.4 7.1 11.9 11.4 11.6 10.1 17.3 11.3 9.9 10.9 11.4 10.5 9.7 12.2 11.6 14.2 13.4 13.4 5.6 18.0 12.8 16.7 13.8 31.0 8.1 11.9 12.2 6.7 10.3 19.0 18.1 12.5 19.2 15.7 13.3 8.5 11.1 8.8 13.9 10.2 12.0 15.7 5.8 10.7 38.6 16.9 8.7 8.7 13.8 16.3 8.1 43.9 9.8 19.0 11.9 28.1 29.5 20.7 14.4 20.7 18.8 13.5 11.9 13.2 13.7 24.6 13.5 16.7 15.5 10.9 45.2 6.3 4.6 3.3 4.5 4.2 6.2 2.1 3.9 4.5 4.5 2.4 3.9 3.5 5.4 4.2 4.2 1.2 3.3 2.6 6.6 6.6 7.9 20.1 8.3 8.1 7.7 6.5 7.0 7.1 7.4 7.1 22.9 35.3 16.2 3.6 20.4 70.4 18.4 20.2 71.7 2.3 18.2 14.4 9.4 5.7 24.3 12.9 10.4 7.5 37.2 22.1 0.0 6.4 9.4 18.1 18.0 19.4 10.7 5.9 8.1 6.3 9.0 16.3 15.3 29.5 22.2 6.4 15.4 8.3 8.7 1.7 6.9 12.5 10.2 13.2 361.2 7.3 4.1 69.0 16.0 5.6 97.0 3.9 10.3 6.0 4.4 10.4 13.4 4.5 25.3 16.5 16.0 3.2 29.7 6.3 13.1 16.4 15.4 10.2 9.4 64.2 78.7 14.9 40.4 6.0 14.4 51.4 EVPL EVPK ENSG00000167880 Envoplakin Q92817 17 76004502-76027306 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 281.2;skin 1: 147.4;vagina: 101.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 26.7;Squamous epithelial cells: 94.1;Suprabasal keratinocytes: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 59.8;MCF7: 40.4;RT4: 87.8;SK-BR-3: 43.2;T-47d: 54.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002220, HPA053969" Enhanced Supported "Intermediate filaments,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" Cytosol "CAB002220: AB_563701, HPA053969: AB_2682326" "unprognostic (2.10e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (4.21e-1)" "unprognostic (1.05e-2)" "unprognostic (1.87e-2)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (1.44e-1)" "unprognostic (7.40e-3)" "unprognostic (2.64e-1)" "unprognostic (2.40e-2)" "unprognostic (2.31e-1)" "unprognostic (3.47e-1)" "unprognostic (7.93e-2)" "unprognostic (3.09e-2)" 1.3 0.3 0.6 1.0 0.6 2.5 2.6 1.1 1.0 47.5 0.8 8.9 11.0 1.5 1.7 281.2 2.1 1.7 0.2 0.6 0.3 17.0 0.3 9.4 0.6 2.8 1.3 0.3 4.0 3.4 1.5 0.3 2.8 8.0 1.5 0.6 42.3 1.8 1.4 147.4 9.1 1.0 0.5 0.3 5.2 0.8 0.6 0.4 10.7 0.1 7.9 12.7 101.9 1.5 28.1 23.4 0.0 0.3 0.2 0.0 9.6 0.2 0.0 0.0 0.0 2.6 16.7 0.0 0.1 0.0 0.0 59.8 0.1 7.8 0.1 0.1 0.2 0.7 19.4 17.4 0.0 0.2 4.2 0.2 12.3 0.2 0.0 0.0 0.0 3.7 0.1 1.1 0.0 40.4 1.0 3.6 0.1 11.9 10.5 11.5 0.1 0.4 16.7 87.8 1.1 0.0 11.4 43.2 0.0 0.2 54.1 0.8 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.2 0.1 0.0 0.6 0.6 1.1 1.0 0.6 0.3 2.8 1.3 2.8 0.5 0.6 1.5 0.2 19.2 19.5 0.0 0.0 11.7 4.7 10.5 26.7 0.3 5.1 2.9 3.7 4.3 16.5 5.5 0.0 0.2 0.2 10.8 1.9 4.4 0.0 4.3 0.6 0.3 20.4 1.3 0.3 0.5 0.2 0.5 12.8 8.9 12.6 0.2 0.0 0.0 0.0 0.0 0.1 5.7 2.0 0.6 2.1 0.1 0.9 0.2 1.8 0.0 0.1 0.0 0.0 0.0 0.1 8.4 7.4 1.9 1.2 4.6 19.3 3.4 13.1 0.1 0.0 0.7 0.7 0.1 1.2 94.1 25.9 0.0 0.4 0.4 15.5 12.9 EXO1 "HEX1, hExoI" ENSG00000174371 "Exonuclease 1" Q9UQ84 1 241847967-241895148 "Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, Immunity, Meiosis" "DNA-binding, Endonuclease, Excision nuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 17.3;lymphoid tissue: 11.1" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Erythroid cells: 7.4;Extravillous trophoblasts: 16.7;Plasma cells: 11.8;Spermatocytes: 9.3;Spermatogonia: 9.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053079, HPA069738" Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA053079: AB_2682037, HPA069738: AB_2732140" "unprognostic (6.33e-3)" "unprognostic (8.54e-3)" "unprognostic (9.47e-3)" "prognostic unfavorable (8.21e-4)" "unprognostic (2.43e-1)" "unprognostic (6.34e-2)" "prognostic unfavorable (6.94e-7)" "unprognostic (1.84e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.40e-2)" "unprognostic (4.81e-3)" "unprognostic (9.40e-2)" "unprognostic (0.00e+0)" "unprognostic (6.72e-2)" "unprognostic (2.29e-1)" "unprognostic (1.75e-1)" "unprognostic (3.57e-1)" 0.5 0.3 0.2 3.3 0.2 17.3 1.2 0.1 0.7 0.5 0.1 3.2 2.9 0.8 0.0 2.5 0.3 0.4 0.2 0.3 0.1 0.3 0.5 0.6 5.8 0.1 0.2 0.2 0.3 0.7 0.1 3.3 0.2 0.2 3.7 0.0 0.5 0.2 0.1 1.8 2.5 1.2 0.2 1.5 1.6 5.7 0.3 11.1 0.4 0.0 6.4 1.2 0.8 0.4 41.3 26.8 43.4 28.6 2.7 6.7 36.5 53.4 17.7 46.7 50.5 33.9 22.5 44.3 25.3 12.6 25.1 40.0 55.5 22.5 54.8 69.5 48.4 41.5 28.8 17.3 1.0 59.8 29.4 1.7 1.1 46.8 12.5 5.7 14.7 43.4 84.6 57.0 37.8 19.0 65.9 33.6 60.4 49.7 26.0 46.2 40.5 47.5 9.6 25.6 48.1 60.9 34.8 27.9 19.5 20.2 25.8 36.6 5.5 44.9 39.5 42.7 72.9 41.5 59.0 71.3 15.6 48.1 54.9 0.8 0.2 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.3 0.2 0.2 0.1 0.7 0.3 0.1 0.1 0.2 0.2 0.2 0.3 0.4 0.2 0.0 0.0 0.3 0.7 0.8 0.1 0.7 0.0 0.0 0.3 0.5 2.3 0.0 0.1 0.0 0.0 5.3 0.2 1.2 0.0 0.1 9.3 0.3 0.4 0.7 0.0 7.4 1.0 0.0 16.7 0.9 1.1 0.5 0.0 4.6 0.4 0.0 3.3 0.0 2.9 0.5 0.0 0.3 0.8 2.1 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 11.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 9.3 9.8 2.7 0.1 4.0 0.8 0.8 1.9 0.3 EXOC1L ENSG00000250821 "Exocyst complex component 1 like" A0A1B0GW35 4 55819790-55837489 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 8 "Theca cells: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 20 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 20 "NK-cells: 1.9" "Cell line enhanced" "Detected in single" "HEK 293: 1.5" "Region enriched" "Detected in single" 4 "pons and medulla: 2.8" "Not detected" "Not detected" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 EXOC2 "FLJ11026, SEC5L1, Sec5p" ENSG00000112685 "Exocyst complex component 2" Q96KP1 6 485154-693139 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.8;Inhibitory neurons: 80.1;Microglial cells: 68.4;Oligodendrocytes: 73.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032093 Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA032093: AB_10611964" "unprognostic (1.61e-1)" "unprognostic (4.69e-1)" "unprognostic (1.52e-1)" "unprognostic (9.32e-2)" "unprognostic (1.91e-2)" "unprognostic (2.48e-1)" "unprognostic (1.82e-3)" "unprognostic (1.34e-1)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (5.32e-2)" "unprognostic (2.02e-1)" "unprognostic (8.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (2.20e-1)" 10.2 8.3 11.0 11.5 11.7 6.6 10.9 11.4 11.2 10.1 11.6 9.1 8.6 8.7 5.2 12.2 6.5 8.9 11.6 11.2 11.5 9.3 10.3 11.3 13.4 11.6 11.6 7.8 6.6 11.6 8.2 18.0 12.5 7.9 10.0 13.4 8.0 7.9 10.1 11.8 9.3 9.2 11.0 13.1 8.9 16.1 11.3 18.6 14.2 10.4 14.1 10.8 9.1 14.4 21.0 15.2 26.0 28.5 23.2 20.8 15.7 18.5 21.5 21.7 25.8 20.4 11.0 15.5 44.0 22.3 32.7 17.7 29.2 32.2 25.7 48.4 30.9 19.8 18.5 20.4 29.1 21.2 18.8 18.1 25.9 15.5 18.0 21.4 36.9 30.0 39.4 11.1 27.3 18.1 28.6 20.6 26.4 18.6 15.1 26.6 22.5 31.3 19.5 22.4 25.4 14.9 14.8 9.0 29.1 48.4 23.2 12.9 54.1 19.6 14.1 24.6 17.4 27.2 56.8 16.4 19.8 17.4 61.0 11.6 9.0 10.2 17.1 11.0 20.9 13.5 17.2 18.3 14.1 14.5 16.2 15.7 2.8 14.8 17.7 11.1 21.1 14.4 11.0 11.7 11.4 11.2 11.2 11.5 11.6 11.6 12.5 11.0 11.3 14.4 12.6 3.2 14.5 35.6 15.9 4.8 3.8 6.2 6.2 9.0 10.1 9.3 8.6 2.8 6.5 5.5 8.4 16.0 18.5 6.1 7.9 6.2 11.0 7.3 7.0 11.1 2.4 8.2 75.8 5.1 7.1 7.6 6.1 8.2 5.1 11.8 8.6 8.2 10.0 8.4 80.1 6.8 12.2 9.0 5.8 3.8 6.8 8.7 5.4 68.4 10.8 4.6 13.4 49.3 73.4 6.9 5.1 9.1 11.3 6.4 4.1 8.2 9.0 9.3 0.0 7.3 8.9 21.8 17.5 9.9 7.7 12.9 18.3 7.4 5.9 6.0 EXOC4 "KIAA1699, MGC27170, SEC8, SEC8L1, Sec8p" ENSG00000131558 "Exocyst complex component 4" Q96A65 7 133253073-134066589 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 238.6;Excitatory neurons: 334.2;Inhibitory neurons: 306.8;Microglial cells: 341.0;Oligodendrocyte precursor cells: 395.6;Oligodendrocytes: 345.9;Rod photoreceptor cells: 231.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031443, HPA031444" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA 10000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA031443: AB_10602496, HPA031444: AB_2673886" "unprognostic (1.70e-1)" "unprognostic (1.62e-2)" "unprognostic (2.05e-1)" "unprognostic (5.09e-2)" "unprognostic (1.03e-1)" "unprognostic (4.06e-3)" "unprognostic (8.63e-2)" "unprognostic (2.33e-1)" "unprognostic (4.40e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (9.78e-3)" "prognostic favorable (6.85e-5)" "unprognostic (5.91e-2)" "unprognostic (2.18e-1)" "unprognostic (3.37e-1)" "unprognostic (3.35e-2)" 20.7 21.1 18.7 13.8 20.2 13.8 21.4 19.3 20.3 22.6 24.3 19.7 13.1 21.5 13.6 24.4 27.3 17.8 15.3 20.9 19.4 17.7 17.8 17.7 16.4 18.4 20.3 30.6 27.3 27.3 16.9 19.6 19.9 18.3 21.5 53.1 16.3 20.5 68.4 25.4 13.5 23.9 18.8 21.0 17.3 18.7 19.1 28.1 26.4 38.5 20.3 21.1 18.6 20.8 40.1 32.2 43.3 43.3 49.7 51.6 15.0 28.6 47.2 25.4 33.2 18.8 54.7 29.8 20.1 54.1 36.9 24.7 23.7 38.8 41.8 45.6 28.2 24.0 31.5 19.9 54.7 32.0 25.1 50.4 47.6 36.3 66.5 55.7 43.5 38.6 35.1 28.8 47.7 26.1 58.5 35.2 32.8 47.5 29.8 25.7 38.7 54.2 40.7 35.2 33.9 53.2 43.0 39.1 46.3 48.9 25.8 29.3 47.9 28.1 14.6 30.0 31.5 45.0 29.4 28.1 82.9 36.4 43.8 10.3 12.0 7.2 11.2 12.9 10.0 8.3 11.6 11.9 16.3 8.1 9.4 9.6 4.0 19.6 11.4 7.2 12.9 11.2 18.7 20.2 19.3 20.3 20.9 19.4 18.4 20.3 19.9 18.8 19.1 20.8 22.9 22.4 22.3 238.6 27.3 18.9 16.3 16.6 25.6 39.9 16.8 15.4 30.9 11.5 18.0 14.7 93.8 17.5 26.7 21.5 3.9 15.0 29.6 27.0 21.2 23.0 17.4 18.7 334.2 18.2 16.6 21.2 34.1 21.0 8.2 32.4 23.2 15.9 18.1 50.5 306.8 21.0 26.4 27.3 14.5 27.6 17.4 20.4 14.2 341.0 23.9 20.4 23.7 395.6 345.9 15.4 17.4 18.8 27.7 13.2 16.3 16.9 29.8 231.5 13.1 26.0 15.3 20.5 13.1 28.2 17.0 11.2 26.2 26.4 21.9 20.1 EXOC6B "KIAA0919, SEC15B, SEC15L2" ENSG00000144036 "Exocyst complex component 6B" Q9Y2D4 2 72175984-72826041 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 50.7" "Cell type enhanced" "Detected in many" "Astrocytes: 210.3;Excitatory neurons: 351.1;Inhibitory neurons: 393.6;Microglial cells: 286.7;Oligodendrocyte precursor cells: 288.5;Oligodendrocytes: 863.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034546, HPA063991" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear bodies" Cytosol "HPA034546: AB_2674218, HPA063991: AB_2685168" "unprognostic (5.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.18e-3)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "unprognostic (1.06e-2)" "unprognostic (9.34e-2)" "unprognostic (1.32e-1)" "unprognostic (2.16e-3)" "unprognostic (3.38e-2)" "unprognostic (2.61e-1)" "unprognostic (4.35e-3)" "unprognostic (4.38e-3)" "unprognostic (1.55e-1)" "unprognostic (1.18e-1)" "unprognostic (5.29e-2)" 11.3 13.4 22.3 4.2 32.7 1.2 8.6 18.8 23.9 12.6 3.2 8.6 7.3 10.1 6.0 15.1 7.8 6.5 50.7 20.7 25.7 7.2 3.8 7.2 3.1 23.9 25.7 15.0 5.0 13.2 6.1 13.0 23.3 8.0 5.7 14.1 7.7 8.9 11.1 26.5 9.1 10.0 16.4 5.2 6.9 6.9 22.2 4.4 10.2 11.5 6.4 9.7 13.0 40.9 21.7 16.3 14.7 17.8 41.2 16.9 25.3 15.6 21.9 13.2 8.6 22.3 3.3 5.6 9.5 26.2 19.6 35.4 12.4 25.7 18.9 4.2 10.1 16.7 11.0 12.8 22.2 2.4 5.5 14.6 36.6 14.9 23.1 20.6 21.8 8.7 1.8 0.0 17.6 7.5 6.4 2.9 15.3 14.9 9.0 3.4 26.4 2.3 12.7 50.1 7.3 6.3 26.7 8.2 10.9 16.1 5.7 2.3 24.3 15.2 12.8 13.1 9.6 5.5 5.9 0.0 17.7 1.2 12.4 1.3 0.5 0.0 0.7 0.4 0.5 0.7 0.5 0.4 0.4 0.7 0.6 0.9 0.0 0.5 0.6 0.1 0.8 0.4 22.3 32.7 18.8 23.9 20.7 25.7 23.9 25.7 23.3 16.4 22.2 40.9 17.8 0.0 4.1 210.3 4.1 26.1 10.2 9.8 14.8 17.4 5.2 5.2 87.1 12.8 5.1 9.2 25.0 15.1 5.0 10.2 5.9 9.3 62.9 5.6 14.5 14.1 3.0 2.1 351.1 11.5 13.2 12.4 30.5 9.2 8.2 11.6 11.4 5.6 4.6 16.8 393.6 6.0 4.1 12.0 7.1 8.2 8.4 5.0 5.4 286.7 2.0 9.9 1.0 288.5 863.3 11.0 8.6 7.5 3.7 8.1 28.2 5.5 8.4 11.1 0.0 13.5 14.7 12.0 4.9 13.1 37.4 24.6 4.7 5.5 4.5 10.7 EXOSC5 "hRrp46p, MGC12901, p12B, RRP41B, RRP46, Rrp46p" ENSG00000077348 "Exosome component 5" Q9NQT4 19 41386374-41397359 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053150, HPA055677" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "HPA053150: AB_2682058, HPA055677: AB_2682882" "unprognostic (1.24e-1)" "unprognostic (5.68e-2)" "unprognostic (2.99e-1)" "unprognostic (2.53e-3)" "unprognostic (7.50e-3)" "unprognostic (5.74e-2)" "unprognostic (3.83e-3)" "unprognostic (9.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.54e-1)" "unprognostic (9.39e-2)" "unprognostic (2.35e-2)" "prognostic unfavorable (3.45e-7)" "unprognostic (6.84e-2)" "unprognostic (2.27e-1)" "unprognostic (7.79e-2)" "unprognostic (7.82e-2)" 12.9 19.4 18.6 14.1 20.2 17.4 14.0 18.9 26.1 12.5 15.1 13.3 11.4 11.3 4.2 21.4 15.1 6.6 16.8 18.8 17.8 9.9 21.7 7.3 22.0 20.8 18.4 14.3 28.6 5.9 7.2 7.4 19.2 11.0 7.2 2.3 16.4 8.4 41.7 23.0 10.8 7.2 19.0 14.3 13.6 11.4 18.3 14.8 11.6 23.1 11.8 14.7 13.9 22.1 58.2 123.5 15.1 48.8 10.7 13.5 39.4 24.5 13.1 44.6 37.0 72.5 47.5 92.9 64.8 12.9 22.8 25.1 33.1 31.3 12.2 66.7 117.3 42.7 45.5 55.7 32.1 76.7 41.8 16.3 69.0 35.6 33.8 12.1 21.1 57.7 57.5 70.2 14.2 88.1 70.2 58.6 56.6 85.2 59.9 66.9 40.9 94.8 17.6 43.1 64.4 47.8 34.6 62.4 68.2 10.5 31.1 95.6 16.2 45.9 37.4 30.1 76.9 109.6 138.5 106.3 34.9 116.0 39.0 15.2 68.2 1.9 41.3 77.7 47.9 66.0 43.3 40.9 110.1 74.0 63.2 55.4 5.0 62.1 48.6 118.7 37.0 48.6 18.6 20.2 18.9 26.1 18.8 17.8 20.8 18.4 19.2 19.0 18.3 22.1 16.1 3.2 4.8 2.3 21.3 30.5 29.0 29.6 44.9 5.5 30.1 44.2 8.4 22.8 16.9 18.4 4.2 28.4 23.5 12.7 37.2 21.7 9.1 5.5 16.7 11.1 8.5 28.0 5.0 21.4 124.0 13.1 16.3 9.1 5.1 24.7 7.1 20.3 28.8 6.7 4.8 18.4 20.3 11.8 13.3 8.5 16.8 18.9 14.2 2.8 18.9 7.0 18.6 4.0 4.3 17.2 15.3 12.4 21.3 28.0 6.6 34.9 12.7 4.1 6.6 17.8 16.0 17.0 33.1 47.4 33.2 21.2 17.0 31.5 34.2 23.8 EXOSC7 "EAP1, hRrp42p, KIAA0116, p8, RRP42, Rrp42p" ENSG00000075914 "Exosome component 7" Q15024 3 44975241-45036066 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036182, HPA057980" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA036182: AB_10673346, HPA057980: AB_2683571" "unprognostic (1.69e-2)" "unprognostic (3.92e-3)" "unprognostic (1.84e-3)" "unprognostic (4.97e-2)" "unprognostic (3.00e-3)" "unprognostic (2.16e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-2)" "unprognostic (2.96e-1)" "unprognostic (7.85e-2)" "unprognostic (1.20e-1)" "unprognostic (7.67e-3)" "prognostic favorable (2.69e-4)" "unprognostic (4.33e-1)" "unprognostic (7.30e-2)" "unprognostic (2.94e-1)" "unprognostic (1.20e-1)" 17.5 44.1 9.5 12.5 9.5 17.2 18.4 10.0 10.4 23.5 10.7 15.3 11.6 20.4 7.0 27.2 17.0 9.1 27.0 9.5 10.9 22.2 18.1 15.0 19.6 10.4 9.8 19.0 18.6 20.1 17.3 15.4 10.1 15.9 10.8 5.9 17.5 15.9 43.8 44.6 13.2 11.2 9.7 15.3 20.0 23.2 10.5 20.2 19.9 36.4 16.8 22.7 22.2 9.8 61.5 55.7 44.9 37.3 45.9 50.0 40.5 26.2 42.2 56.0 57.7 93.3 47.8 77.4 40.3 45.6 42.6 33.9 55.9 72.2 46.0 52.3 49.2 67.5 64.5 91.5 88.7 95.3 26.5 44.1 45.6 61.2 123.6 36.5 54.8 84.9 107.4 37.8 40.3 63.2 68.6 167.9 54.3 55.2 78.4 33.8 41.7 117.7 51.0 85.5 20.9 31.4 37.0 31.6 39.7 38.4 46.7 77.9 39.3 28.8 43.0 48.3 71.7 47.1 47.5 92.6 42.4 131.6 26.2 6.8 41.3 7.6 38.8 41.5 43.6 71.3 44.6 40.2 66.0 59.7 51.8 41.4 2.1 58.3 31.5 40.2 47.7 45.4 9.5 9.5 10.0 10.4 9.5 10.9 10.4 9.8 10.1 9.7 10.5 9.8 25.0 35.3 30.1 16.0 23.2 61.8 68.8 97.2 47.3 29.5 23.9 43.2 39.0 21.5 46.5 35.0 18.8 67.8 22.1 8.6 135.0 51.7 3.9 23.7 34.8 24.0 13.1 19.6 19.9 46.7 62.4 32.7 23.0 21.7 15.2 33.0 18.2 28.6 46.5 20.2 22.5 19.3 79.3 14.2 22.6 8.3 47.8 17.4 26.6 8.4 20.6 37.6 33.0 10.6 14.0 41.7 10.3 41.0 19.4 74.8 17.7 47.4 34.3 23.4 13.1 25.7 53.9 53.7 66.3 35.5 74.2 63.1 26.2 52.2 24.3 56.3 EXPH5 SLAC2-B ENSG00000110723 "Exophilin 5" Q8NEV8 11 108505435-108593768 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skin 1: 25.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Basal keratinocytes: 107.7;Glandular and luminal cells: 89.5;Respiratory ciliated cells: 98.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 15 "cerebellum: 67.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 7.9;hTERT-HME1: 11.2;RT4: 20.5;SK-BR-3: 9.7" "Group enriched" "Detected in many" 4 "cerebellum: 20.9;cerebral cortex: 6.7" "Region enriched" "Detected in many" 8 "cerebellum: 30.9" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "unprognostic (1.34e-3)" "unprognostic (8.36e-2)" "unprognostic (1.18e-1)" "prognostic favorable (3.42e-6)" "unprognostic (2.91e-1)" "prognostic favorable (1.46e-4)" "unprognostic (4.57e-3)" "prognostic favorable (5.12e-4)" "unprognostic (1.26e-1)" "unprognostic (3.03e-1)" "unprognostic (5.56e-3)" "unprognostic (1.33e-1)" "prognostic favorable (2.43e-4)" "unprognostic (1.18e-2)" "unprognostic (2.57e-1)" "unprognostic (3.36e-1)" "unprognostic (4.51e-1)" 0.4 0.1 1.3 0.5 2.5 0.2 2.9 67.7 2.3 2.2 12.8 3.9 0.7 0.7 2.7 7.4 1.7 0.3 0.2 2.1 1.9 2.4 7.7 3.9 0.1 1.5 3.6 0.3 1.0 4.7 0.5 2.8 4.6 1.5 4.4 0.3 4.4 0.3 0.1 25.8 0.8 0.4 1.1 0.2 3.2 0.7 1.7 0.8 1.0 0.2 1.4 0.7 3.8 3.4 3.9 0.4 0.2 0.1 0.0 0.1 3.2 0.2 0.1 0.0 0.6 1.0 5.9 0.0 0.2 0.2 0.9 7.9 5.7 2.1 0.2 0.1 1.7 1.6 0.8 0.0 0.5 0.8 0.1 0.1 3.3 0.0 11.2 0.5 0.0 1.3 3.0 0.0 3.1 0.6 1.0 0.0 0.2 6.4 2.4 0.0 0.1 0.0 0.6 20.5 1.4 0.8 1.0 9.7 0.2 1.1 6.4 0.1 0.1 0.0 2.3 0.0 1.1 0.1 0.0 0.0 0.1 0.4 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.5 0.5 0.8 0.9 0.1 0.2 0.0 0.1 1.3 2.5 67.7 2.3 2.1 1.9 1.5 3.6 4.6 1.1 1.7 3.4 0.6 147.4 60.0 18.6 0.9 107.7 12.9 16.6 58.6 0.6 14.1 8.6 5.7 4.3 65.3 20.2 14.6 44.5 2.4 47.9 3.9 5.4 10.3 74.8 7.8 2.5 4.9 3.2 9.0 4.9 4.9 5.6 20.9 89.5 1.3 0.9 0.7 24.2 3.8 0.0 4.9 38.6 14.2 0.6 15.2 2.3 0.6 1.8 5.4 16.9 1.3 0.5 1.0 3.0 0.6 3.6 17.5 0.0 1.5 30.4 1.9 3.7 98.5 1.4 0.0 0.3 2.1 1.1 0.5 46.9 72.2 54.6 2.8 0.4 29.1 19.3 EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111826 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 229.6;Inhibitory neurons: 421.4;Microglial cells: 144.3;Oligodendrocyte precursor cells: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 95.5;fHDF/TERT166: 82.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain NA Yes 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.85e-1)" 5.1 4.2 2.0 5.2 2.5 1.1 4.3 2.3 2.3 7.6 3.9 7.7 14.1 4.9 2.9 5.5 3.8 5.8 7.0 3.4 1.3 3.8 13.3 7.9 3.0 1.1 2.1 5.0 5.5 3.3 1.8 11.1 1.0 5.0 8.2 2.7 3.2 7.7 1.5 7.8 11.7 6.1 1.4 5.1 5.3 2.4 1.2 3.0 5.2 2.4 3.8 11.8 4.2 1.9 29.3 8.5 13.5 5.5 22.8 23.0 5.9 51.5 95.5 40.9 39.4 10.0 3.1 0.5 24.8 82.1 24.0 19.8 5.0 31.4 55.7 12.5 9.9 1.5 5.9 6.5 10.0 0.0 1.6 10.8 10.8 38.8 38.5 47.7 28.1 2.9 0.9 7.4 18.7 3.2 1.8 0.2 4.6 13.7 10.1 0.0 4.1 1.3 23.1 7.6 4.5 4.0 8.0 3.9 9.2 32.6 5.3 0.5 32.0 35.2 28.7 32.0 15.8 5.5 5.1 2.4 36.5 0.0 9.2 0.1 0.4 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.3 0.1 2.0 2.5 2.3 2.3 3.4 1.3 1.1 2.1 1.0 1.4 1.2 1.9 21.1 19.2 6.0 127.3 3.0 54.8 23.0 27.7 10.2 23.6 7.8 10.8 6.5 24.3 13.7 7.3 14.6 6.5 5.1 49.2 0.0 37.3 1.8 17.7 37.1 25.9 4.8 1.7 229.6 20.1 3.9 32.6 11.7 18.2 7.0 108.3 16.8 32.9 2.5 10.1 421.4 25.5 4.1 37.9 13.9 2.7 17.4 9.6 19.6 144.3 8.1 5.9 4.1 162.8 101.8 27.4 16.1 36.1 5.3 19.3 44.9 4.9 14.2 22.4 0.0 17.1 36.4 0.6 5.1 12.6 47.3 12.2 4.2 35.0 26.3 26.8 EXTL1 "EXTL, MGC70794" ENSG00000158008 "Exostosin like glycosyltransferase 1" Q92935 1 26019884-26036464 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.2;skeletal muscle: 12.7;tongue: 29.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.3;Breast glandular cells: 8.8;Excitatory neurons: 22.7;Horizontal cells: 10.1;Melanocytes: 7.2;Oligodendrocyte precursor cells: 10.6" "Cancer enriched" "Detected in some" 13 "melanoma: 21.7" "Group enriched" "Detected in many" 11 "amygdala: 10.3;basal ganglia: 9.8;cerebral cortex: 14.2;hippocampal formation: 11.5;white matter: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010726, HPA037749" Uncertain Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 79000 "Cluster 47: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" Centrosome Vesicles "HPA010726: , HPA037749: AB_10805350" "unprognostic (2.00e-1)" "unprognostic (1.10e-2)" "unprognostic (8.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.47e-2)" "unprognostic (6.14e-3)" "unprognostic (3.78e-2)" "unprognostic (1.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.44e-2)" "unprognostic (3.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-3)" "unprognostic (2.27e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-2)" 0.2 1.0 10.3 0.0 9.8 0.0 0.8 0.0 14.2 0.4 0.0 1.0 0.1 3.6 0.1 0.5 0.7 0.3 3.5 11.5 0.0 0.4 0.0 0.2 0.2 0.1 0.6 1.1 1.5 0.0 0.9 0.3 0.4 0.4 0.0 0.8 0.5 0.2 12.7 2.3 0.3 1.3 0.0 3.5 0.3 0.6 0.9 0.0 0.2 29.8 0.0 0.3 0.4 6.9 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.7 0.0 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.2 0.6 0.0 0.2 2.4 0.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 150.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 9.8 0.0 14.2 11.5 0.0 0.1 0.6 0.4 0.0 0.9 6.9 0.1 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 15.3 8.8 1.8 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 22.7 0.0 0.0 0.4 0.0 0.2 0.0 0.4 0.0 0.0 0.1 10.1 5.1 0.0 0.0 0.0 0.3 0.6 1.5 0.0 7.2 2.8 0.0 0.4 0.0 10.6 1.9 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.4 0.4 0.2 0.2 0.0 0.0 1.0 0.0 1.1 0.1 0.1 EYA2 EAB1 ENSG00000064655 "EYA transcriptional coactivator and phosphatase 2" O00167 20 46894624-47188844 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 55.6" "Cell type enhanced" "Detected in many" "Astrocytes: 153.8;Basal prostatic cells: 47.5;Basal respiratory cells: 50.4;Endometrial ciliated cells: 43.7;Glandular and luminal cells: 53.8;Oligodendrocyte precursor cells: 48.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 69.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 40.1;SCLC-21H: 58.3;U-266/70: 110.9;U-266/84: 139.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027024, HPA059291" Uncertain Supported Cytosol NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA027024: AB_1848334, HPA059291: AB_2683967" "unprognostic (1.08e-1)" "unprognostic (5.71e-3)" "unprognostic (4.03e-1)" "prognostic favorable (4.30e-5)" "unprognostic (3.32e-2)" "unprognostic (1.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.65e-1)" "unprognostic (7.06e-2)" "unprognostic (2.15e-1)" "unprognostic (2.78e-1)" "unprognostic (4.17e-3)" "unprognostic (1.56e-1)" 12.0 1.5 12.3 2.4 14.1 0.0 11.0 15.6 12.3 55.6 11.2 9.3 0.3 17.2 3.7 34.2 34.0 1.8 5.0 10.7 11.8 4.7 2.1 2.2 0.8 14.6 14.4 0.7 1.9 9.4 5.3 6.3 13.7 23.6 3.1 1.2 31.2 9.3 2.5 5.3 1.1 1.8 11.8 0.6 8.9 5.6 13.4 18.8 14.6 3.4 6.6 4.9 16.5 11.0 0.2 4.4 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.7 2.5 1.9 0.3 40.1 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.1 0.3 2.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 7.7 0.1 0.0 0.6 0.1 0.0 0.1 0.8 0.5 0.0 0.0 58.3 0.0 0.0 24.8 0.0 3.0 5.3 0.2 0.0 0.0 4.5 0.3 8.8 110.9 139.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 14.1 15.6 12.3 10.7 11.8 14.6 14.4 13.7 11.8 13.4 11.0 0.4 0.0 0.0 153.8 0.9 0.6 47.5 50.4 14.8 0.4 7.8 7.6 0.5 2.8 33.0 0.0 6.2 27.7 0.0 2.5 0.0 0.9 0.2 43.7 3.9 0.6 1.2 0.0 1.5 0.0 3.0 4.8 9.2 53.8 1.3 9.8 0.4 3.3 7.4 0.0 5.1 0.6 34.6 0.0 0.4 0.3 0.0 1.1 3.6 13.1 2.6 0.0 0.0 48.7 1.0 1.1 1.7 0.7 3.4 10.9 0.0 6.3 22.2 0.4 0.0 0.3 2.8 0.2 7.4 16.0 0.3 10.8 0.6 4.2 3.6 34.6 EZR VIL2 ENSG00000092820 Ezrin P15311 6 158765741-158819368 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004035, HPA021616, CAB047324, CAB075739" Enhanced Enhanced "Plasma membrane" NA NA 42000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB004035: AB_2100309, CAB047324: , CAB075739: AB_2665745, HPA021616: AB_1848342" "unprognostic (4.79e-3)" "unprognostic (1.48e-1)" "unprognostic (1.97e-2)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (5.59e-2)" "prognostic favorable (9.56e-8)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-2)" "unprognostic (9.00e-2)" 88.2 186.6 100.7 98.4 99.5 135.2 59.8 86.0 96.8 77.1 224.4 133.5 158.8 35.6 78.4 260.3 114.6 116.1 116.3 96.2 95.6 159.1 57.9 173.2 185.6 97.6 105.3 44.7 112.6 447.4 42.8 233.0 91.7 81.4 103.6 10.7 89.9 72.2 46.9 187.8 257.1 36.6 99.3 75.6 273.7 55.9 98.9 108.8 126.1 25.5 216.3 219.0 98.6 91.1 668.3 355.4 86.5 125.0 9.3 10.3 502.7 204.7 67.1 225.7 189.2 420.9 357.7 667.1 197.2 235.2 108.5 497.7 172.2 228.0 259.5 235.3 111.2 14.0 204.9 187.5 223.2 167.7 98.9 16.6 172.9 212.9 205.1 191.4 150.2 90.8 134.9 316.7 132.3 175.9 239.3 199.6 144.5 180.6 117.6 176.9 40.7 152.5 462.1 198.6 156.3 127.2 358.5 507.7 37.9 391.5 124.1 218.5 195.3 72.6 233.4 101.1 319.9 216.5 212.8 566.9 45.4 84.9 88.5 177.2 83.4 103.7 195.9 190.8 233.2 466.5 205.6 245.1 181.9 389.7 108.6 146.3 36.2 133.6 202.9 84.5 385.7 298.2 100.7 99.5 86.0 96.8 96.2 95.6 97.6 105.3 91.7 99.3 98.9 91.1 47.4 951.9 547.8 111.3 799.6 614.7 809.5 202.4 247.0 11.2 240.4 144.4 311.0 154.4 726.2 156.3 0.0 406.1 372.4 806.8 97.8 302.3 10.2 782.9 75.4 71.0 159.9 46.5 0.4 256.1 560.3 213.1 500.5 844.5 119.0 40.8 25.4 37.5 113.3 0.0 0.5 415.3 179.0 79.1 820.5 32.8 135.5 297.5 321.9 12.2 110.5 35.7 62.8 2.0 0.7 618.3 631.2 294.2 564.9 416.7 694.2 238.1 1248.4 5.1 249.8 205.5 136.3 52.5 61.7 430.4 726.5 1243.4 483.8 102.3 312.9 1142.8 F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.4;stomach 1: 44.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 109.9;Distal enterocytes: 124.7;Gastric mucus-secreting cells: 74.5;Glandular and luminal cells: 74.7;Paneth cells: 86.1;Suprabasal keratinocytes: 168.4;Urothelial cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 42.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.0" "Cell line enhanced" "Detected in many" "PC-3: 126.0;RPTEC TERT1: 205.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" 1.0 1.3 0.8 6.2 0.9 1.7 8.0 0.5 0.8 3.6 8.9 59.4 45.8 2.9 4.8 8.2 8.2 29.9 4.6 0.5 0.8 31.8 7.1 4.1 1.4 1.7 2.2 0.5 23.6 5.2 1.5 3.9 1.4 5.0 53.0 2.6 8.9 11.5 0.3 37.5 41.0 2.7 1.0 3.8 44.0 0.6 0.9 1.1 8.3 0.2 1.6 27.5 5.8 0.8 32.7 52.1 4.3 0.2 1.5 4.0 33.1 1.6 17.1 0.9 2.7 45.0 81.8 0.0 69.5 3.7 78.1 54.4 27.1 24.0 1.5 0.1 26.8 0.8 1.0 32.8 10.6 0.0 0.3 5.5 67.3 8.0 49.8 8.0 84.9 7.8 0.4 0.0 0.1 17.6 3.8 0.1 5.7 17.9 126.0 0.1 0.0 0.8 205.9 58.5 2.1 0.4 12.3 12.6 0.3 48.5 5.3 0.3 57.1 0.1 31.8 0.1 0.3 4.8 1.0 0.1 18.7 0.0 1.4 11.9 10.0 1.8 0.4 3.2 2.1 0.5 3.8 1.9 4.7 0.1 3.4 2.1 42.0 0.7 0.5 0.5 1.0 4.0 0.8 0.9 0.5 0.8 0.5 0.8 1.7 2.2 1.4 1.0 0.9 0.8 0.3 9.6 3.7 0.0 0.9 109.9 17.8 4.5 10.8 0.5 10.5 6.3 0.3 32.9 12.7 31.3 0.0 5.4 0.2 124.7 1.9 28.0 0.0 40.9 5.1 1.2 13.1 2.5 0.2 15.0 7.9 2.9 74.5 74.7 2.5 1.0 1.1 9.6 0.9 0.0 1.4 50.8 4.1 1.9 3.8 0.0 0.0 2.1 1.8 1.0 2.6 0.0 0.0 0.0 0.0 44.7 86.1 0.0 0.1 34.1 62.9 19.3 25.0 2.0 0.0 0.4 2.8 0.9 1.3 37.0 168.4 2.1 2.1 0.1 50.7 116.0 F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Cytotrophoblasts: 82.7;Hepatocytes: 253.4;Syncytiotrophoblasts: 59.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Group enriched" "Detected in some" 23 "Hep G2: 32.8;OE19: 125.5" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" 1.1 0.0 0.3 3.2 1.4 3.7 0.6 4.4 1.3 0.1 142.8 0.3 0.9 0.1 0.2 0.2 3.5 17.6 2.7 4.4 1.6 1.5 176.2 0.9 2.2 1.9 2.2 0.0 0.8 0.0 1.6 46.9 2.4 1.3 0.6 1.0 6.2 0.0 0.2 1.3 0.3 1.1 0.8 1.8 4.9 0.5 2.2 0.5 0.4 0.2 2.3 3.8 0.1 4.2 0.0 0.6 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 32.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 125.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.1 8.1 0.0 0.2 0.0 0.0 1.4 0.2 0.4 0.0 0.3 0.0 7.0 0.0 0.0 0.0 6.2 1.1 0.3 1.4 4.4 1.3 4.4 1.6 1.9 2.2 2.4 0.8 2.2 4.2 0.0 3.2 0.6 1.6 0.7 0.1 6.1 0.0 0.0 0.3 0.7 0.3 9.4 74.4 1.9 0.0 2.1 82.7 0.1 0.3 0.0 2.4 2.4 0.9 0.0 2.4 25.2 0.0 5.4 0.2 2.3 5.3 4.1 0.2 0.0 2.8 3.6 253.4 5.3 0.0 2.6 0.1 0.0 12.3 0.4 0.3 0.0 7.1 3.6 0.0 18.2 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.1 1.8 0.0 0.2 3.1 0.1 0.0 2.4 0.2 0.5 0.5 0.0 0.0 59.5 2.5 0.0 0.0 11.8 FA2H "FAAH, FAXDC1, FLJ25287, SPG35" ENSG00000103089 "Fatty acid 2-hydroxylase" Q7L5A8 16 74712955-74774831 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 183.9;stomach 1: 61.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 85.1;Oligodendrocyte precursor cells: 61.3;Oligodendrocytes: 307.9;Paneth cells: 75.2;Urothelial cells: 192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 38.1;HAP1: 48.6;JURKAT: 89.8;OE19: 61.5;SK-BR-3: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056614, HPA077840" Approved Uncertain "Nuclear membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear membrane" "HPA056614: AB_2683191, HPA077840: AB_2686858" "unprognostic (1.33e-1)" "unprognostic (4.97e-2)" "unprognostic (9.19e-2)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (5.85e-2)" "unprognostic (1.48e-2)" "unprognostic (2.47e-2)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (6.01e-2)" "prognostic favorable (5.01e-6)" "unprognostic (1.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-2)" "unprognostic (2.11e-3)" 0.3 0.3 41.7 4.3 89.1 0.3 2.8 77.9 63.0 1.9 11.7 21.2 10.3 0.2 2.2 7.9 1.8 17.8 0.3 46.1 56.1 8.2 0.2 1.4 0.7 129.2 79.6 0.0 8.4 10.1 0.6 0.7 106.0 1.9 19.4 0.4 11.0 0.7 0.0 8.5 14.4 1.1 65.2 0.5 61.1 2.9 75.2 4.7 2.0 0.1 5.9 26.3 2.2 183.9 9.2 38.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.5 0.0 20.8 21.0 0.0 0.2 0.0 2.0 3.6 48.6 0.6 0.1 0.0 1.6 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 89.8 0.0 0.0 0.0 15.2 0.8 0.0 0.9 61.5 2.1 0.0 0.0 1.6 23.4 15.6 6.5 0.0 0.0 28.8 0.0 1.3 8.6 0.0 0.0 0.0 0.1 0.0 0.2 1.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.7 89.1 77.9 63.0 46.1 56.1 129.2 79.6 106.0 65.2 75.2 183.9 0.0 0.0 1.3 1.0 2.6 0.5 11.1 8.5 1.8 0.0 5.0 3.3 0.2 8.6 14.6 0.0 0.0 0.5 0.2 43.0 7.9 13.5 10.8 2.4 0.5 0.2 6.7 0.0 0.7 14.2 0.2 1.1 85.1 4.5 0.0 0.1 0.0 0.0 0.1 0.0 0.9 34.8 4.1 0.0 0.0 4.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 61.3 307.9 38.4 75.2 0.4 6.2 22.9 17.6 0.2 10.5 0.0 0.0 0.0 0.6 2.4 3.3 12.4 0.9 0.1 0.2 0.0 15.3 192.8 FAAH2 "AMDD, FAAH-2, FLJ31204, RP11-479E16.1" ENSG00000165591 "Fatty acid amide hydrolase 2" Q6GMR7 X 57286706-57489193 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 75.7;Excitatory neurons: 110.2;Inhibitory neurons: 131.2;Oligodendrocyte precursor cells: 110.6;Oligodendrocytes: 105.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 16.7" "Lineage enriched" "Detected in many" 9 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.0;HDLM-2: 13.0;RPMI-8226: 26.6;U-266/70: 20.9;U-266/84: 11.4" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.37e-1)" "unprognostic (1.78e-2)" "unprognostic (7.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.02e-1)" "unprognostic (4.51e-2)" "unprognostic (7.93e-3)" "unprognostic (4.47e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.99e-4)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.47e-13)" "unprognostic (9.16e-3)" "unprognostic (2.27e-1)" "prognostic favorable (2.66e-4)" "prognostic favorable (6.83e-5)" 0.8 1.6 1.1 1.6 0.8 0.4 6.8 3.3 1.0 3.6 0.9 3.2 3.0 1.3 4.4 4.9 6.1 1.7 0.3 0.7 2.6 7.2 10.5 3.2 2.6 1.2 1.3 0.4 15.1 13.4 6.7 0.8 1.2 7.3 4.0 7.0 7.1 4.1 0.1 9.6 3.0 0.3 0.5 0.7 4.6 0.1 2.2 7.3 4.8 0.2 7.0 3.4 3.4 0.9 3.4 0.3 0.1 0.2 0.1 0.1 3.1 0.0 0.1 0.0 0.0 2.4 14.0 0.1 4.0 0.0 0.0 0.6 1.1 2.5 0.0 13.0 6.9 0.4 3.1 1.0 0.0 1.5 0.0 0.0 4.2 0.0 0.0 0.1 0.0 1.4 1.6 6.3 0.0 1.4 0.8 0.0 2.4 2.9 0.0 0.0 2.4 26.6 8.1 4.5 2.4 0.1 0.2 3.9 0.0 5.7 3.9 0.1 0.0 0.0 0.3 0.0 0.2 20.9 11.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 5.0 1.8 8.0 3.4 0.0 0.5 7.7 0.9 0.3 0.9 0.0 1.2 16.7 1.6 1.1 0.8 3.3 1.0 0.7 2.6 1.2 1.3 1.2 0.5 2.2 0.9 0.2 3.2 7.8 75.7 4.0 2.7 12.1 19.0 15.4 4.4 6.0 4.2 0.3 4.3 14.9 5.5 18.8 5.5 0.2 4.2 9.8 11.9 0.0 12.6 1.1 0.4 13.2 0.0 110.2 14.1 2.5 1.1 15.8 12.2 0.0 0.9 1.1 11.3 0.7 1.7 131.2 5.4 26.4 0.0 0.3 0.0 0.6 0.6 3.6 45.0 0.6 1.2 0.0 110.6 105.3 11.9 3.8 0.4 14.4 7.4 4.8 5.6 25.1 11.8 0.0 0.5 1.0 0.0 0.0 7.1 6.7 5.6 16.7 0.3 4.0 9.2 FABP9 "PERF, PERF15, T-FABP" ENSG00000205186 "Fatty acid binding protein 9" Q0Z7S8 8 81458253-81461579 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "skin 1: 40.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073619 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA073619: AB_2732229" "unprognostic (2.99e-1)" 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 40.9 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.4 0.0 0.2 0.2 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FADS1 "D5D, FADS6, FADSD5, LLCDL1, TU12" ENSG00000149485 "Fatty acid desaturase 1" O60427 11 61799627-61829318 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 521.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042705 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA042705: AB_10795709" "unprognostic (8.28e-2)" "unprognostic (3.54e-1)" "unprognostic (1.29e-1)" "unprognostic (1.99e-1)" "unprognostic (8.17e-3)" "unprognostic (1.40e-1)" "unprognostic (1.99e-2)" "unprognostic (3.23e-3)" "unprognostic (7.88e-2)" "unprognostic (1.94e-2)" "unprognostic (4.10e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.95e-9)" "unprognostic (2.29e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.79e-4)" "prognostic unfavorable (1.33e-4)" 26.2 67.7 43.1 19.8 39.2 9.7 13.6 38.4 40.7 19.6 70.7 9.5 5.5 21.3 6.6 5.2 17.4 14.5 22.6 39.3 58.5 9.7 52.8 20.3 9.8 57.9 62.1 27.5 10.0 27.2 21.3 21.1 52.2 19.6 4.9 35.1 6.4 15.8 17.5 15.5 6.7 20.5 46.4 8.0 9.4 11.9 68.7 8.1 6.0 7.8 9.2 12.7 10.2 56.0 66.3 170.1 159.1 41.1 313.2 521.2 46.4 42.0 204.5 69.9 118.9 53.3 143.2 2.3 43.4 60.5 177.2 84.7 130.8 114.1 51.7 12.2 18.4 107.9 191.2 98.9 169.1 23.4 10.4 238.1 38.3 154.7 74.7 73.8 64.1 104.7 59.9 118.6 70.1 18.6 78.6 23.6 94.2 5.5 63.0 85.4 162.5 231.2 81.5 29.0 80.7 89.6 106.7 1.7 90.0 58.4 38.6 98.6 62.1 71.8 70.8 74.2 50.6 112.9 111.3 55.4 42.6 108.9 61.4 7.5 33.2 6.2 12.1 40.4 2.6 2.5 4.0 4.9 28.0 8.7 2.3 5.4 2.6 6.9 17.4 23.6 2.9 15.7 43.1 39.2 38.4 40.7 39.3 58.5 57.9 62.1 52.2 46.4 68.7 56.0 10.3 6.4 77.9 28.7 3.2 2.7 2.5 48.5 1.2 78.9 2.6 3.7 30.4 8.6 25.3 12.9 27.1 9.5 12.4 0.9 0.0 15.2 8.7 4.9 30.7 16.6 9.7 46.3 9.4 33.4 50.0 34.9 6.1 7.8 37.9 65.3 9.3 74.5 37.2 69.0 14.7 0.6 16.2 21.7 21.0 16.4 29.8 27.6 32.0 12.2 32.0 70.5 6.2 13.6 27.4 7.6 0.0 21.4 2.1 6.4 0.1 1.1 8.0 91.9 0.0 40.3 31.9 6.5 17.5 2.3 1.4 9.3 5.5 75.2 1.4 1.6 FADS2 "D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13" ENSG00000134824 "Fatty acid desaturase 2" O95864 11 61792980-61867354 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 364.1" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Endometrial stromal cells: 57.7;Hepatocytes: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 1141.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006741 Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA006741: AB_1078796" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (8.34e-2)" "unprognostic (4.33e-3)" "unprognostic (4.63e-2)" "unprognostic (2.42e-2)" "unprognostic (4.51e-2)" "unprognostic (4.35e-3)" "unprognostic (2.01e-1)" "unprognostic (4.21e-2)" "unprognostic (8.95e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.00e-7)" "unprognostic (6.19e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "prognostic unfavorable (3.42e-4)" 23.7 364.1 140.2 34.7 126.7 28.0 59.6 128.5 135.0 68.0 157.0 24.2 31.9 86.3 27.7 10.6 34.6 20.2 27.7 131.8 164.8 20.3 126.7 33.4 16.5 175.1 186.2 29.1 9.8 80.0 50.8 40.6 155.1 97.7 13.2 41.5 24.3 188.7 12.3 131.6 15.9 125.3 152.0 11.5 14.1 27.8 222.9 34.1 10.4 8.8 31.2 24.6 27.9 134.2 14.6 492.6 655.8 345.0 551.3 1141.8 167.2 86.3 658.3 109.0 288.2 31.4 149.6 3.8 11.4 172.3 167.8 15.7 436.4 709.5 52.7 6.9 11.8 297.9 106.5 72.0 421.9 18.9 15.9 430.9 25.8 383.4 39.1 170.3 324.4 254.4 17.9 212.1 52.0 13.5 166.4 104.7 291.5 0.7 150.1 206.1 13.9 663.1 392.1 4.4 197.4 260.8 49.9 1.4 23.5 164.0 21.5 197.7 139.2 14.0 120.5 9.8 13.1 115.7 110.3 39.7 13.0 96.3 131.2 4.4 6.0 6.9 8.5 8.7 2.0 1.4 3.1 4.6 10.1 3.7 1.8 3.8 2.8 6.6 7.4 13.0 2.9 4.9 140.2 126.7 128.5 135.0 131.8 164.8 175.1 186.2 155.1 152.0 222.9 134.2 3.2 9.6 18.8 69.9 2.0 1.7 1.3 26.9 0.0 9.1 4.7 3.0 4.2 1.5 15.1 3.7 4.2 1.7 5.2 0.5 0.0 6.9 2.2 4.7 57.7 12.2 5.4 26.7 7.4 17.8 22.0 21.0 5.1 9.5 5.1 28.3 2.5 55.8 20.5 5.0 7.7 0.2 22.4 7.2 3.1 5.3 25.7 7.0 8.8 15.0 20.7 32.1 8.2 38.7 11.9 5.1 0.0 23.7 1.4 16.9 0.1 0.7 5.4 13.2 0.0 23.8 29.5 1.3 0.5 1.2 0.6 3.1 2.5 28.3 2.0 0.9 FAF1 "CGI-03, hFAF1, HFAF1s, UBXD12, UBXN3A" ENSG00000185104 "Fas associated factor 1" Q9UNN5 1 50437028-50960267 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 202.4;Excitatory neurons: 296.7;Inhibitory neurons: 278.9;Microglial cells: 177.1;Oligodendrocyte precursor cells: 269.9;Oligodendrocytes: 424.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018253, CAB072814" Approved Supported Nucleoplasm NA NA 12000 "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB072814: , HPA018253: AB_1848351" "unprognostic (1.52e-1)" "unprognostic (1.25e-2)" "unprognostic (6.49e-3)" "unprognostic (4.69e-2)" "unprognostic (6.35e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (1.82e-1)" "unprognostic (9.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.01e-3)" "unprognostic (6.42e-3)" 18.2 16.8 21.0 9.2 22.0 21.0 18.5 21.8 27.5 18.9 18.7 23.7 12.4 18.2 11.7 23.1 15.7 8.7 34.9 22.3 22.1 21.5 23.6 14.9 13.1 21.5 21.5 19.9 26.2 23.2 20.6 10.6 22.0 18.5 12.7 19.6 18.1 16.3 67.9 28.1 16.4 13.4 21.8 14.0 18.2 47.8 21.2 22.2 18.3 37.6 14.1 21.4 18.7 25.9 37.4 27.1 23.1 39.3 22.4 21.1 33.9 35.5 32.1 53.9 48.8 30.4 26.0 59.9 25.7 30.5 47.5 27.2 37.3 33.1 45.9 40.1 33.5 49.9 33.5 31.6 36.4 54.3 28.5 19.8 29.4 57.0 69.4 27.8 29.5 44.5 58.9 0.2 28.1 15.0 56.6 43.0 30.6 49.3 19.2 52.1 50.7 0.0 54.9 33.1 0.3 28.6 32.3 64.9 56.4 32.0 20.4 64.1 18.2 30.4 37.3 37.8 0.2 45.1 50.6 69.3 0.0 77.6 35.7 1.1 2.1 4.9 4.0 2.7 5.5 2.5 3.6 4.0 3.6 4.2 4.3 2.8 0.7 4.3 3.5 2.9 6.1 1.6 21.0 22.0 21.8 27.5 22.3 22.1 21.5 21.5 22.0 21.8 21.2 25.9 17.9 6.4 18.2 202.4 26.9 21.4 38.5 27.8 33.6 19.9 16.9 16.9 43.9 11.5 27.2 16.5 27.1 14.2 18.0 13.1 29.4 8.8 75.1 15.1 15.6 14.2 11.4 44.6 296.7 11.6 28.2 16.0 29.0 16.9 5.7 19.2 10.4 18.2 11.4 16.8 278.9 17.8 6.1 13.6 18.0 117.2 11.1 15.4 16.0 177.1 8.9 20.0 15.5 269.9 424.4 8.5 9.7 10.9 35.4 18.3 20.0 28.3 32.7 33.0 6.6 26.2 20.3 36.9 15.6 37.9 28.1 15.3 27.9 19.6 21.6 34.1 FAM104A FLJ14775 ENSG00000133193 "Family with sequence similarity 104 member A" Q969W3 17 73207353-73236753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 44.8;testis: 153.0" "Group enriched" "Detected in all" 4 "Early spermatids: 1305.1;Late spermatids: 1771.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021459, HPA079514" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "HPA021459: AB_1848361, HPA079514: " "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (5.02e-3)" "unprognostic (3.23e-2)" "unprognostic (2.28e-2)" "unprognostic (3.05e-2)" "prognostic unfavorable (2.12e-7)" "unprognostic (5.19e-2)" "unprognostic (2.31e-2)" "unprognostic (4.88e-2)" "unprognostic (4.20e-2)" "unprognostic (1.20e-2)" "prognostic unfavorable (1.26e-10)" "unprognostic (6.70e-2)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" 16.6 11.7 13.1 14.1 13.0 44.8 15.3 16.9 14.0 14.4 11.1 14.7 12.6 11.7 12.5 17.8 11.1 10.4 12.4 12.9 11.3 10.8 13.9 12.8 17.8 12.0 11.5 12.2 15.0 12.2 16.0 17.8 11.5 14.1 12.4 14.0 12.3 11.1 17.1 21.6 12.8 11.2 11.4 17.0 21.7 153.0 12.6 20.9 11.8 12.0 16.9 13.4 14.8 13.7 41.8 33.5 16.7 31.0 24.7 23.1 54.1 33.4 34.7 35.9 36.9 28.3 26.3 24.3 26.7 32.2 35.0 26.0 21.4 24.3 38.7 28.6 28.7 35.4 29.1 43.5 32.9 31.1 58.1 24.6 31.6 31.9 23.2 23.7 42.6 28.8 28.0 39.6 43.6 28.5 55.7 21.5 22.9 30.7 42.5 30.1 46.3 23.5 27.6 33.7 27.3 36.1 19.6 28.2 36.7 31.0 39.4 31.8 29.8 42.3 49.1 29.1 39.4 38.5 41.5 29.8 37.9 33.7 31.9 72.4 49.4 87.7 57.1 44.6 55.5 53.5 69.6 65.7 48.8 55.8 50.1 60.9 81.9 68.9 49.8 31.7 128.5 82.5 13.1 13.0 16.9 14.0 12.9 11.3 12.0 11.5 11.5 11.4 12.6 13.7 37.1 9.6 10.2 7.5 24.2 57.0 20.7 42.3 17.6 17.7 22.5 21.1 5.6 22.8 26.9 22.0 6.2 122.3 23.0 20.8 31.3 32.7 1305.1 21.9 16.0 23.9 19.8 103.6 14.2 25.3 70.1 19.4 28.5 24.6 29.2 20.4 18.2 18.5 35.6 26.9 14.1 22.9 26.4 21.8 34.2 1771.9 35.1 25.5 24.9 10.3 32.2 20.2 33.0 10.6 11.3 32.1 20.1 24.0 30.4 32.8 26.4 18.9 27.4 19.7 6.6 14.8 43.7 277.3 60.7 29.9 65.8 324.9 32.7 21.3 20.7 51.8 FAM107A "DRR1, TU3A" ENSG00000168309 "Family with sequence similarity 107 member A" O95990 3 58564117-58627610 "Predicted intracellular proteins" "Cell cycle, Growth regulation, Stress response" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 1923.8;choroid plexus: 1389.1" "Cell type enhanced" "Detected in many" "Adipocytes: 196.3;Astrocytes: 81.9;Endothelial cells: 121.3;Hepatic stellate cells: 150.6;Muller glia cells: 125.0" "Cancer enriched" "Detected in many" 6 "glioma: 110.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 20.7;HUVEC TERT2: 64.9" "Low region specificity" "Detected in all" HPA055888 Enhanced Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA055888: AB_2682957" "unprognostic (1.20e-2)" "unprognostic (1.19e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.11e-1)" "unprognostic (7.80e-3)" "prognostic favorable (3.38e-4)" "unprognostic (1.92e-1)" "unprognostic (1.64e-1)" "unprognostic (5.73e-2)" "unprognostic (7.82e-3)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (1.33e-2)" "unprognostic (2.82e-1)" "unprognostic (1.92e-1)" "unprognostic (7.95e-3)" 73.2 7.5 1824.7 8.3 1801.2 0.3 58.6 1490.8 1923.8 34.5 1389.1 36.9 5.4 36.3 53.3 29.2 87.0 16.0 140.4 1745.7 1736.7 45.0 5.5 93.2 3.1 1611.9 1644.5 11.8 23.3 5.9 109.6 29.4 1613.0 80.5 16.0 85.1 40.6 38.0 26.3 23.3 45.2 42.5 1564.5 25.7 37.7 5.7 1698.7 43.9 51.4 32.8 8.6 68.9 41.6 1770.4 0.0 0.0 0.9 0.0 20.7 1.3 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.1 5.8 0.0 0.2 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1.4 0.0 0.1 0.1 0.3 64.9 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.0 3.6 0.3 0.2 0.2 0.1 0.1 0.0 0.1 1.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1824.7 1801.2 1490.8 1923.8 1745.7 1736.7 1611.9 1644.5 1613.0 1564.5 1698.7 1770.4 196.3 6.4 5.5 81.9 0.5 2.2 50.8 0.3 2.2 5.2 2.3 1.3 26.5 4.3 3.2 38.6 52.1 0.1 0.4 0.0 9.8 1.1 14.5 23.2 2.4 121.3 3.6 2.7 1.4 0.2 0.0 18.4 0.0 39.3 1.3 5.9 150.6 1.6 0.0 3.3 5.3 0.0 0.0 2.2 3.7 32.4 32.9 1.9 5.4 14.0 0.0 125.0 0.0 2.0 0.6 0.3 0.0 11.7 1.3 7.3 0.2 4.5 2.3 50.2 6.6 6.6 10.4 0.7 0.4 0.4 2.7 0.0 1.0 0.5 0.0 2.2 FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 71.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 71.7;Extravillous trophoblasts: 138.2;Langerhans cells: 74.2;Macrophages: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 543.5;eosinophil: 163.4;intermediate monocyte: 160.6;non-classical monocyte: 248.6" "Group enriched" "Detected in all" 9 "granulocytes: 543.5;monocytes: 248.6" "Cell line enhanced" "Detected in all" "SK-BR-3: 84.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "CAB034110: AB_1562838, HPA069240: AB_2686103" "unprognostic (6.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "unprognostic (4.90e-3)" "unprognostic (5.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (9.64e-3)" "unprognostic (1.17e-2)" "unprognostic (6.42e-3)" "unprognostic (4.21e-3)" 4.2 5.5 4.2 5.9 5.2 8.8 9.0 3.1 3.6 10.1 3.9 5.5 10.0 2.5 4.7 39.3 2.5 2.3 4.0 2.8 3.4 8.8 3.6 12.3 6.7 5.5 5.3 2.8 5.5 11.0 7.9 6.6 5.6 19.3 3.2 1.2 18.4 3.6 4.0 71.2 9.7 1.1 3.3 23.4 6.1 3.7 6.6 6.9 7.6 0.6 7.8 9.2 18.4 3.6 27.7 7.3 4.1 7.6 4.4 1.9 27.8 8.5 4.7 5.3 4.7 16.0 16.9 8.9 3.7 5.3 7.6 43.7 3.3 22.2 4.4 7.3 2.3 18.6 4.9 4.2 2.0 5.1 6.3 1.2 27.1 7.3 7.1 1.6 3.6 8.1 10.2 21.5 4.9 16.4 14.3 13.8 5.3 17.7 12.3 14.1 7.0 11.7 4.1 19.6 7.7 9.1 7.4 84.0 3.8 1.7 34.9 7.5 4.8 12.6 9.1 11.5 9.6 7.8 7.3 3.8 2.0 13.2 9.2 543.5 28.3 163.4 13.2 160.6 11.7 7.0 23.7 27.2 36.2 11.7 28.1 27.9 15.3 6.9 248.6 3.9 43.0 24.2 4.2 5.2 3.1 3.6 2.8 3.4 5.5 5.3 5.6 3.3 6.6 3.6 3.5 0.0 7.0 0.0 18.5 32.6 17.0 31.6 71.7 0.3 26.7 20.1 2.9 7.2 15.7 11.0 0.0 41.5 24.3 5.1 1.9 10.1 9.9 3.0 1.7 8.0 10.8 16.2 0.5 6.0 138.2 3.6 5.1 5.2 51.5 1.4 17.2 0.7 20.0 5.0 0.4 8.8 16.2 36.7 74.2 24.3 3.4 70.0 7.2 1.9 29.9 0.3 25.7 0.5 0.1 13.4 7.8 1.9 3.5 20.9 16.1 2.4 7.4 2.6 6.6 1.1 4.3 3.4 4.9 57.7 36.8 31.3 26.1 14.2 10.4 24.6 FAM111B CANP ENSG00000189057 "Family with sequence similarity 111 member B" Q6SJ93 11 59107185-59127412 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "B-cells: 12.8;Erythroid cells: 9.1;Plasma cells: 8.8;Squamous epithelial cells: 7.1;Undifferentiated cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3;naive B-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038637 Uncertain Approved Nucleoplasm,Cytosol No Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA038637: AB_10672522" "unprognostic (2.31e-1)" "unprognostic (2.68e-2)" "unprognostic (1.80e-3)" "unprognostic (6.94e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.49e-3)" "unprognostic (1.40e-2)" "unprognostic (4.85e-2)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.01e-2)" "unprognostic (1.24e-5)" "unprognostic (2.94e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-3)" "unprognostic (1.24e-1)" 0.9 0.5 0.5 5.9 0.6 4.8 2.7 2.8 1.8 1.0 0.1 5.6 3.4 1.0 0.5 3.4 0.5 0.8 0.3 0.6 1.1 0.4 2.5 1.1 12.3 0.5 1.0 0.2 0.6 0.9 0.0 1.7 0.7 1.0 5.8 1.3 0.8 0.4 0.4 4.4 4.0 2.0 0.1 1.8 3.2 0.8 0.6 18.0 0.9 0.1 13.3 1.7 1.0 2.1 72.6 18.5 26.6 0.4 2.7 4.9 0.3 53.5 26.7 31.2 46.1 38.7 28.0 89.8 35.4 15.7 26.3 54.7 39.5 36.2 55.2 46.8 9.5 9.8 32.3 16.9 0.1 0.3 11.1 1.2 1.2 30.3 2.4 6.0 16.9 24.1 2.8 81.9 37.2 27.3 57.7 0.6 0.3 43.2 21.0 60.1 39.7 34.7 16.8 61.2 5.2 16.9 44.4 50.8 8.7 9.7 56.2 5.0 9.4 24.1 52.4 73.5 49.6 62.6 48.4 0.6 35.0 0.4 35.4 0.2 0.1 0.1 0.1 0.0 0.1 3.3 0.2 0.3 0.1 2.6 0.1 0.1 1.6 0.0 0.1 0.1 0.7 0.1 0.5 0.6 2.8 1.8 0.6 1.1 0.5 1.0 0.7 0.1 0.6 2.1 0.7 0.0 0.0 0.0 12.8 4.2 2.2 4.2 1.8 0.0 2.5 4.2 0.3 0.0 1.4 0.0 0.0 1.1 1.4 4.0 0.0 0.8 0.0 0.9 1.6 1.2 0.0 9.1 0.0 0.0 0.4 1.5 3.6 1.9 0.0 6.3 0.0 0.2 3.9 0.0 0.0 4.4 2.0 0.3 1.6 0.0 0.0 2.4 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 1.3 0.0 8.8 0.7 0.5 0.1 1.6 0.0 0.0 1.3 1.8 0.1 1.0 7.1 2.7 0.1 3.2 1.1 10.4 1.6 FAM117B "ALS2CR13, FLJ38771" ENSG00000138439 "Family with sequence similarity 117 member B" Q6P1L5 2 202634969-202769757 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.8;Inhibitory neurons: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003229, HPA028746" Uncertain Approved Nucleoplasm,Centrosome Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Centrosome "HPA003229: AB_2246696, HPA028746: AB_2672760" "unprognostic (1.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-2)" "unprognostic (4.59e-2)" "unprognostic (1.07e-2)" "unprognostic (4.07e-3)" "unprognostic (1.55e-2)" "unprognostic (4.84e-2)" "unprognostic (6.21e-2)" "unprognostic (2.55e-2)" "unprognostic (8.40e-3)" "unprognostic (5.75e-1)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (3.18e-1)" "unprognostic (8.59e-2)" "unprognostic (1.37e-3)" 3.1 7.5 5.1 4.5 5.4 2.9 3.3 7.0 7.1 2.7 0.7 4.9 4.3 2.9 2.9 5.4 3.8 3.0 1.8 5.0 6.3 4.9 1.9 2.9 7.2 3.1 3.8 5.1 4.6 7.3 3.5 6.9 3.6 5.1 4.7 2.6 3.3 3.0 1.5 5.0 3.7 2.0 3.3 5.4 4.1 5.8 6.4 9.6 2.8 1.8 7.4 3.8 3.2 4.1 2.0 2.4 10.5 7.2 3.5 1.9 10.2 0.6 0.9 0.6 1.1 3.1 4.2 8.2 6.5 1.2 1.6 1.9 9.0 4.6 1.7 0.2 7.2 6.9 4.3 11.6 2.8 5.9 3.0 2.6 6.3 1.3 1.9 4.7 2.8 10.8 10.1 1.6 0.6 3.9 16.1 12.1 10.7 5.8 4.5 12.5 2.1 9.8 5.5 5.2 17.7 15.4 8.0 5.3 3.9 8.7 2.2 8.1 1.7 1.2 2.4 1.9 1.1 5.9 3.6 10.8 2.4 4.5 1.3 0.4 3.9 1.5 1.3 8.2 3.4 8.1 3.0 2.7 4.5 7.7 8.2 5.7 2.2 4.4 9.1 1.5 1.2 3.1 5.1 5.4 7.0 7.1 5.0 6.3 3.1 3.8 3.6 3.3 6.4 4.1 9.7 3.2 7.5 13.1 21.5 17.2 2.9 3.0 12.0 4.9 8.1 4.3 4.9 12.8 2.6 18.4 4.2 8.4 8.8 11.7 0.0 10.2 2.2 8.6 6.5 4.9 25.8 3.0 45.8 6.4 6.3 6.1 7.1 10.1 5.7 15.3 8.2 2.2 2.8 6.7 49.7 11.8 2.0 27.4 13.9 1.4 13.1 17.1 3.6 23.4 17.1 1.7 3.1 29.1 29.4 5.8 9.7 23.7 5.2 6.7 4.9 5.9 3.0 2.7 6.6 2.0 4.1 5.0 16.3 29.2 19.9 2.7 10.1 11.1 13.8 6.0 FAM126A "DRCTNNB1A, HCC, HYCC1, hyccin" ENSG00000122591 "Family with sequence similarity 126 member A" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 133.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042873: AB_2678207" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-4)" "unprognostic (1.35e-1)" "unprognostic (9.76e-3)" "unprognostic (1.30e-2)" "unprognostic (7.23e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (6.04e-7)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (9.03e-4)" 14.9 4.7 5.0 8.5 6.9 4.2 12.2 4.4 6.5 9.7 7.9 9.7 9.4 8.7 1.4 12.2 6.7 11.4 10.5 12.1 4.5 4.7 8.5 13.7 11.5 5.0 5.9 6.6 6.2 2.3 5.0 14.8 5.4 5.9 4.4 4.9 6.8 4.8 25.0 4.9 6.9 11.5 4.5 11.8 4.6 12.0 6.3 4.2 6.6 15.3 9.2 9.4 11.2 7.8 22.4 12.4 63.6 22.3 61.3 100.9 10.6 103.0 101.8 41.6 63.9 19.8 10.6 13.3 15.9 82.6 87.2 7.7 44.3 14.7 72.6 6.6 22.4 14.7 18.1 13.0 48.0 19.3 15.7 41.1 9.2 85.0 61.3 83.4 42.5 7.5 30.4 58.6 77.5 7.9 10.8 24.2 63.0 0.1 22.9 15.7 63.5 9.5 13.1 11.2 10.4 0.1 38.1 0.4 19.2 52.5 8.2 20.4 51.0 150.0 18.3 71.8 37.4 67.2 30.6 60.9 91.1 12.5 112.6 4.7 2.9 13.7 1.4 7.8 1.3 6.4 2.6 1.3 3.9 7.4 0.9 1.5 0.3 2.1 9.8 1.6 4.0 2.5 5.0 6.9 4.4 6.5 12.1 4.5 5.0 5.9 5.4 4.5 6.3 7.8 27.8 3.2 15.1 19.6 29.1 25.5 5.1 8.3 15.9 60.3 5.4 32.4 21.9 2.8 4.2 3.7 2.1 11.8 28.8 0.5 0.0 6.8 49.0 12.5 22.4 31.4 7.7 19.8 13.6 4.8 15.5 42.9 2.6 11.3 8.2 8.6 26.0 17.7 15.2 16.8 13.6 3.0 2.0 25.1 55.2 22.4 20.2 31.5 35.6 47.8 24.0 6.8 11.3 23.6 133.2 3.6 1.4 19.5 26.4 4.7 8.3 5.7 2.4 4.6 19.7 24.0 31.7 72.2 11.1 35.0 24.0 6.0 20.6 12.2 4.7 6.5 FAM160A1 FLJ43373 ENSG00000164142 "Family with sequence similarity 160 member A1" Q05DH4 4 151409176-151670503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 32.3;skeletal muscle: 34.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 11.9;Excitatory neurons: 15.8;Oligodendrocyte precursor cells: 19.1;Suprabasal keratinocytes: 14.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 11 "cerebellum: 13.8" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 2.5" "Lineage enriched" "Detected in single" 14 "dendritic cells: 2.5" "Cell line enhanced" "Detected in many" "A-431: 8.6;HeLa: 10.0;hTERT-HME1: 9.2;SiHa: 8.9;SK-BR-3: 7.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA046348 Enhanced Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA046348: AB_10966145" "unprognostic (1.96e-1)" "unprognostic (3.40e-1)" "unprognostic (1.21e-3)" "unprognostic (2.37e-2)" "unprognostic (2.54e-2)" "unprognostic (1.38e-1)" "unprognostic (5.33e-2)" "unprognostic (4.55e-2)" "unprognostic (1.52e-1)" "unprognostic (7.21e-3)" "unprognostic (1.30e-3)" "unprognostic (2.39e-1)" "unprognostic (1.51e-12)" "unprognostic (2.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (1.28e-1)" 0.6 1.3 0.8 0.3 0.7 1.8 4.4 13.8 1.2 3.2 32.3 3.3 1.9 1.6 4.0 7.8 2.7 0.9 3.4 1.2 0.0 3.4 0.7 1.9 0.2 0.6 0.6 2.4 10.2 8.3 1.3 0.5 0.8 2.2 3.4 6.7 4.7 1.5 34.5 13.4 2.0 1.1 0.3 0.5 2.5 3.4 0.4 1.5 6.8 16.5 2.3 2.2 3.4 0.2 8.6 0.7 0.0 0.2 0.0 0.1 2.9 0.3 1.4 0.8 0.2 3.6 3.0 0.0 0.8 0.3 2.6 7.4 2.1 6.1 0.9 0.0 3.3 0.0 10.0 0.9 0.0 0.0 0.2 0.2 7.0 0.0 9.2 2.4 0.2 0.7 0.0 0.0 0.5 1.2 0.0 0.0 2.8 2.8 0.8 0.0 2.0 0.2 5.1 5.5 1.2 0.4 8.9 7.8 0.2 2.2 3.3 0.0 0.0 0.4 3.7 0.2 1.4 0.0 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 13.8 1.2 1.2 0.0 0.6 0.6 0.8 0.3 0.4 0.2 0.1 3.2 2.0 1.3 0.0 11.9 6.6 2.9 10.8 0.1 2.7 1.9 1.8 0.0 5.2 0.0 0.0 0.3 0.5 5.9 0.0 1.6 3.3 5.9 0.6 0.4 0.0 0.0 15.8 1.8 0.6 0.6 6.1 10.8 1.3 0.3 0.0 0.5 0.3 8.4 2.4 2.3 0.0 0.0 2.1 1.5 0.0 0.6 0.0 1.0 0.0 2.5 0.0 19.1 1.3 1.9 0.3 0.0 1.4 7.9 2.2 0.7 1.3 4.7 0.0 1.0 0.4 6.1 5.8 11.6 14.5 1.6 0.2 0.3 1.8 8.6 FAM162A "C3orf28, E2IG5" ENSG00000114023 "Family with sequence similarity 162 member A" Q96A26 3 122384176-122412334 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 625.3;Distal tubular cells: 540.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035856, HPA075611" Approved Supported Mitochondria NA NA 19000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA035856: AB_10611965, HPA075611: " "unprognostic (1.17e-2)" "unprognostic (1.42e-1)" "unprognostic (5.64e-2)" "unprognostic (1.10e-1)" "unprognostic (3.99e-1)" "unprognostic (7.84e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (5.91e-3)" "unprognostic (8.74e-2)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.06e-1)" "unprognostic (4.10e-2)" "prognostic favorable (3.93e-4)" 49.0 105.7 54.8 31.3 60.2 39.9 43.9 57.3 82.2 84.5 57.1 145.9 56.1 49.5 59.4 207.6 49.7 46.2 174.2 57.1 58.5 107.6 200.3 32.0 32.9 55.9 57.2 84.3 133.9 116.6 51.0 17.6 55.6 74.6 149.0 83.5 59.8 49.2 141.0 89.8 56.3 44.6 56.6 31.7 93.2 43.6 58.8 34.7 44.1 142.6 42.7 76.9 131.5 55.6 132.0 27.7 40.4 75.6 72.1 66.4 20.7 52.9 46.8 49.0 123.9 69.4 58.7 142.1 89.2 18.2 40.3 89.8 73.5 128.1 130.0 74.0 55.1 115.6 44.0 125.8 47.4 114.0 39.6 77.3 65.5 46.7 97.9 164.3 66.0 137.7 79.2 55.6 71.1 52.0 116.9 137.9 59.5 294.9 144.4 69.5 57.8 186.9 144.3 314.9 60.1 48.1 39.4 92.4 114.3 59.9 57.9 55.7 47.0 48.4 34.6 28.7 55.6 108.8 39.9 144.8 143.3 109.7 22.8 9.9 25.8 75.7 58.3 68.2 86.9 75.3 79.5 74.0 84.6 68.1 85.1 88.6 8.5 50.6 75.9 70.4 80.4 38.8 54.8 60.2 57.3 82.2 57.1 58.5 55.9 57.2 55.6 56.6 58.8 55.6 55.7 28.9 46.0 41.1 68.2 128.1 155.3 625.3 82.0 31.5 80.6 109.5 338.4 84.4 188.6 130.6 47.9 51.4 47.9 477.5 540.0 148.2 102.5 82.0 30.1 49.8 106.9 47.7 33.0 177.6 47.8 78.7 84.6 79.2 85.7 59.3 44.6 280.4 92.7 38.7 30.4 374.3 240.1 66.7 108.9 33.1 134.5 61.2 104.9 7.5 108.9 79.7 45.3 22.1 21.6 141.6 313.2 148.6 61.2 121.4 186.2 466.2 95.5 29.9 105.2 83.2 315.3 146.4 68.3 315.1 132.8 47.2 66.0 121.1 358.4 210.9 FAM162B "bA86F4.2, C6orf189" ENSG00000183807 "Family with sequence similarity 162 member B" Q5T6X4 6 116752197-116765719 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 65.2" "Group enriched" "Detected in some" 4 "Adipocytes: 34.6;Sertoli cells: 65.7;Smooth muscle cells: 105.1" "Cancer enriched" "Detected in many" 18 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 8.7;BJ hTERT+: 23.5;BJ hTERT+ SV40 Large T+ RasG12V: 22.1;HHSteC: 6.3;HSkMC: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036112, HPA060342" Enhanced NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA036112: AB_10696649, HPA060342: AB_2684258" "unprognostic (1.81e-1)" "unprognostic (5.65e-3)" "unprognostic (1.54e-1)" "unprognostic (3.38e-1)" "unprognostic (5.45e-2)" "unprognostic (1.86e-5)" "unprognostic (8.29e-2)" "unprognostic (1.24e-1)" "unprognostic (4.19e-2)" "unprognostic (2.44e-2)" "unprognostic (7.32e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.22e-2)" "unprognostic (1.72e-1)" "unprognostic (2.73e-3)" "unprognostic (4.34e-2)" 14.7 14.9 3.3 0.8 4.4 0.0 10.9 1.9 7.0 13.2 2.5 3.3 0.9 5.8 7.5 4.4 10.1 5.2 9.1 4.6 2.7 4.5 0.9 17.9 1.5 3.0 2.5 5.7 1.7 3.7 6.6 65.2 2.7 6.2 2.1 0.2 8.2 13.4 5.4 3.0 2.3 3.7 2.7 0.1 3.5 2.5 2.8 1.8 9.7 10.6 1.2 7.9 9.9 4.7 0.0 0.0 0.0 0.0 2.3 0.1 0.0 8.7 23.5 3.7 22.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.4 1.9 7.0 4.6 2.7 3.0 2.5 2.7 2.7 2.8 4.7 34.6 0.0 0.0 1.3 0.0 1.3 0.1 0.0 1.2 0.0 0.9 0.8 0.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 16.9 0.7 15.7 13.7 0.0 0.0 14.8 0.0 0.2 14.1 0.0 0.4 0.0 0.1 3.6 0.0 0.5 0.0 6.9 0.0 0.0 0.0 2.1 2.2 2.1 0.7 1.8 3.7 0.0 0.0 0.0 6.6 0.5 0.2 0.0 5.3 0.0 0.2 0.0 0.1 0.0 0.1 65.7 2.2 105.1 10.3 5.9 0.6 0.9 0.5 2.3 0.1 0.0 0.0 FAM174A "NS5ATP6, TMEM157, UNQ1912" ENSG00000174132 "Family with sequence similarity 174 member A" Q8TBP5 5 100535374-100586741 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 154.5;Respiratory ciliated cells: 222.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 55.8" "Lineage enriched" "Detected in all" 10 "granulocytes: 55.8" "Cell line enhanced" "Detected in all" "U-266/84: 61.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019539 Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" Cytosol "HPA019539: AB_2293743" "unprognostic (2.34e-1)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (9.02e-3)" "prognostic unfavorable (2.57e-6)" "unprognostic (5.55e-3)" "unprognostic (3.06e-1)" "unprognostic (2.60e-1)" "unprognostic (3.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.73e-2)" "unprognostic (7.69e-2)" "prognostic favorable (5.48e-4)" "unprognostic (1.74e-1)" "unprognostic (2.65e-1)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" 16.1 23.1 13.0 8.1 14.4 2.8 15.3 13.4 16.5 11.4 23.3 12.6 11.2 12.1 12.1 24.3 34.8 7.5 19.5 13.8 18.6 17.3 15.7 17.2 5.6 13.9 14.0 10.1 22.6 29.3 27.4 15.1 14.9 18.2 8.5 16.8 17.4 11.8 42.8 30.3 10.3 8.0 13.9 10.2 15.5 22.0 14.6 5.3 13.6 24.7 5.4 13.0 16.9 14.6 10.3 10.7 4.3 13.6 10.3 8.4 15.1 23.1 12.9 9.3 12.7 2.2 13.1 1.8 46.2 10.1 16.2 8.6 3.6 15.1 7.0 12.8 10.9 1.3 18.6 6.4 13.9 5.3 12.4 10.7 35.4 7.2 5.5 21.3 14.3 5.3 3.8 13.7 15.9 20.7 1.6 11.1 2.4 1.2 29.1 3.6 16.2 18.2 17.0 12.3 8.6 23.4 16.2 14.5 13.7 5.0 13.9 11.5 16.1 11.7 7.4 19.0 18.5 44.3 61.5 2.4 14.5 7.1 10.4 7.9 4.9 7.1 3.3 5.5 5.1 2.8 3.3 4.0 4.4 3.3 2.9 3.8 55.8 5.5 5.7 4.4 4.4 3.3 13.0 14.4 13.4 16.5 13.8 18.6 13.9 14.0 14.9 13.9 14.6 14.6 40.8 32.1 31.8 13.1 13.8 88.1 31.4 80.3 43.3 29.7 57.3 31.2 17.4 34.3 54.7 29.5 4.2 44.5 10.0 17.8 43.0 30.6 33.2 154.5 13.8 27.1 34.8 20.6 26.0 30.0 40.3 26.9 18.8 25.3 13.3 8.1 35.0 30.6 23.5 30.3 38.3 32.3 85.5 16.8 22.1 10.1 18.0 14.1 49.8 15.9 17.1 75.4 6.2 19.1 25.1 30.2 23.3 24.5 60.7 28.1 23.2 40.0 222.5 42.3 13.1 48.7 24.3 91.5 20.7 59.6 115.1 50.3 13.8 18.4 18.9 43.1 FAM189A2 "C9orf61, X123" ENSG00000135063 "Family with sequence similarity 189 member A2" Q15884 9 69324567-69392558 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 48.3;thyroid gland: 58.2" "Group enriched" "Detected in many" 5 "Alveolar cells type 1: 157.0;Astrocytes: 256.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;NTERA-2: 5.1;RPTEC TERT1: 1.8;RT4: 2.3;SK-MEL-30: 5.0;SuSa: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029411, HPA057207" Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA029411: AB_10602338, HPA057207: AB_2683369" "unprognostic (2.04e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.16e-6)" "unprognostic (2.24e-1)" "unprognostic (3.93e-2)" "unprognostic (3.47e-2)" "unprognostic (2.89e-2)" "unprognostic (2.09e-1)" "unprognostic (2.71e-3)" "unprognostic (7.84e-2)" "unprognostic (1.07e-2)" "prognostic favorable (1.75e-5)" "unprognostic (3.42e-1)" "unprognostic (2.41e-1)" "unprognostic (4.82e-2)" "unprognostic (1.14e-1)" 6.0 4.7 12.8 0.4 15.0 0.0 13.7 15.8 11.2 26.0 9.2 7.1 1.2 6.8 1.7 5.2 6.8 1.6 13.3 12.2 15.7 4.7 0.2 22.3 0.6 20.1 16.7 24.6 7.3 6.0 7.6 1.5 17.1 11.1 1.1 4.4 6.2 3.4 48.3 12.4 4.0 4.9 16.3 0.4 13.7 1.3 19.8 5.6 58.2 9.0 0.9 7.9 4.6 15.1 0.0 0.0 0.2 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.7 0.7 0.0 0.0 0.6 1.6 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 5.1 0.3 0.0 0.0 0.1 0.0 1.8 2.3 0.0 0.0 0.0 0.0 5.0 1.9 0.1 0.0 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 15.0 15.8 11.2 12.2 15.7 20.1 16.7 17.1 16.3 19.8 15.1 12.1 157.0 23.3 256.3 0.4 3.3 4.9 1.9 7.4 2.1 18.4 39.6 14.6 0.0 26.9 1.8 0.0 1.2 0.4 1.5 0.0 0.9 0.1 19.9 2.8 8.0 0.0 0.0 0.7 0.6 0.1 1.7 11.7 33.0 0.0 2.0 2.2 0.0 0.3 0.0 3.9 0.4 0.0 0.3 1.3 0.0 0.0 0.4 19.6 20.6 0.0 35.1 0.0 7.1 2.1 3.5 1.2 0.0 0.2 3.7 0.2 0.2 2.3 1.0 0.0 3.8 3.8 0.1 0.6 1.9 2.4 0.3 1.0 0.7 0.7 1.8 FAM210B "C20orf108, dJ1167H4.1, DKFZP434A1114" ENSG00000124098 "Family with sequence similarity 210 member B" Q96KR6 20 56358974-56368663 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 449.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 299.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042652 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA042652: AB_2678098" "unprognostic (3.29e-1)" "prognostic favorable (5.44e-4)" "unprognostic (3.24e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-1)" "unprognostic (3.34e-2)" "unprognostic (9.45e-2)" "prognostic favorable (4.26e-4)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" "prognostic favorable (1.44e-10)" "unprognostic (1.08e-1)" "unprognostic (3.27e-2)" "unprognostic (1.84e-1)" "unprognostic (3.00e-1)" 38.2 87.6 32.1 13.9 34.1 85.2 62.0 30.0 33.6 43.7 37.7 39.8 24.7 36.5 45.7 31.1 40.1 40.6 43.9 33.9 32.6 34.6 100.3 28.2 13.9 29.6 33.8 108.9 41.5 32.7 28.1 36.7 29.9 66.8 30.6 30.0 54.9 58.7 75.2 36.5 23.3 34.2 29.6 19.6 34.2 14.1 35.9 20.6 28.4 102.2 20.0 32.5 32.7 29.1 19.9 7.5 29.3 71.6 83.2 93.4 57.1 23.8 53.4 42.6 48.7 13.9 9.6 1.6 12.1 40.9 24.6 56.2 15.9 68.7 71.0 2.9 24.9 12.2 16.9 132.0 54.4 1.3 7.4 80.2 75.2 24.1 34.0 49.3 69.4 10.2 93.6 12.7 52.7 20.6 10.4 5.4 24.9 29.0 46.7 0.1 60.4 15.9 21.9 22.9 40.4 72.9 57.9 124.6 299.1 62.3 55.0 11.1 48.4 37.8 25.2 61.0 14.7 9.9 10.9 0.4 30.0 7.7 25.2 2.3 2.3 6.9 1.7 3.3 1.3 1.1 1.9 2.3 1.7 1.3 2.0 1.9 1.0 1.4 1.5 1.5 2.3 1.0 32.1 34.1 30.0 33.6 33.9 32.6 29.6 33.8 29.9 29.6 35.9 29.1 30.3 16.0 29.3 4.2 7.4 24.9 85.4 28.2 70.6 10.3 57.5 98.8 56.8 54.3 19.3 16.5 39.6 77.7 13.5 23.8 64.6 27.9 1.0 41.4 49.0 28.8 50.9 449.3 5.7 19.5 26.3 46.1 44.9 37.4 19.1 47.5 46.1 154.5 28.0 1.7 6.6 28.6 20.3 44.1 21.2 4.7 66.8 26.2 37.4 5.6 36.6 27.8 14.4 4.0 8.4 35.7 15.3 155.7 9.4 48.7 34.1 46.1 15.6 19.2 19.7 28.1 37.1 1.1 9.4 68.6 32.5 41.9 14.6 123.4 33.4 56.3 FAM220A "ACPIN1, C7orf70, MGC12966, SIPAR" ENSG00000178397 "Family with sequence similarity 220 member A" Q7Z4H9 7 6329411-6348981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 89.7;testis: 55.9" "Group enriched" "Detected in many" 13 "Early spermatids: 280.0;Late spermatids: 363.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055050 Approved Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA055050: AB_2682684" "unprognostic (3.49e-2)" "unprognostic (3.53e-1)" "unprognostic (2.69e-2)" "unprognostic (9.79e-2)" "unprognostic (3.26e-2)" "unprognostic (4.02e-2)" "prognostic unfavorable (5.17e-6)" "unprognostic (2.78e-1)" "unprognostic (1.43e-2)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (8.84e-3)" "unprognostic (1.14e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (3.71e-2)" 7.1 8.6 13.6 6.9 14.7 2.6 8.3 17.5 17.0 9.1 9.3 6.2 5.4 10.3 7.4 11.5 7.6 7.6 13.8 15.3 13.6 8.2 6.4 6.2 9.9 11.7 12.7 10.7 9.8 19.2 0.6 7.9 12.4 8.0 5.3 11.5 8.4 8.3 89.7 10.1 4.9 9.3 12.5 7.9 6.1 55.9 13.7 12.0 11.7 39.1 10.4 9.6 0.5 13.4 26.9 16.6 11.9 28.0 27.0 22.7 13.1 13.4 16.6 15.9 18.5 10.5 14.6 22.2 15.1 15.9 31.8 19.2 18.2 11.3 20.6 15.5 11.7 7.3 10.0 12.6 29.2 13.5 10.8 12.7 37.5 11.9 28.5 15.3 15.0 16.4 14.6 20.7 13.9 20.9 8.4 24.7 27.8 14.0 21.4 21.6 17.9 18.7 14.7 9.6 12.1 21.0 18.8 23.0 28.6 23.9 22.1 34.9 11.4 12.5 28.5 20.6 17.5 19.7 37.2 23.2 14.6 24.1 39.3 6.6 4.2 8.0 4.7 3.5 4.4 9.1 5.4 6.5 7.7 7.7 8.4 6.8 2.0 12.9 3.8 6.8 6.6 3.7 13.6 14.7 17.5 17.0 15.3 13.6 11.7 12.7 12.4 12.5 13.7 13.4 4.1 3.2 1.1 1.3 8.1 7.8 4.9 6.2 12.0 2.9 6.0 6.9 9.2 0.0 8.2 1.8 6.2 6.3 5.4 3.8 1.9 4.9 280.0 6.0 5.5 4.6 6.1 7.8 4.7 4.8 7.5 6.8 7.7 4.8 1.3 4.4 6.4 3.5 6.2 0.0 4.7 4.2 4.1 6.8 10.5 363.4 8.4 7.4 3.6 2.8 7.1 5.2 6.2 4.0 3.9 4.8 2.1 13.2 3.9 5.5 3.3 2.8 3.4 2.3 0.0 6.3 5.4 23.7 11.4 10.3 10.1 8.2 5.2 3.9 3.4 6.7 FAM221B C9orf128 ENSG00000204930 "Family with sequence similarity 221 member B" A6H8Z2 9 35816391-35828747 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 2.9;testis: 9.8" "Group enriched" "Detected in some" 12 "Early spermatids: 266.3;Late spermatids: 122.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA026577 Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA026577: AB_1845810" "unprognostic (1.23e-1)" "unprognostic (5.32e-2)" "unprognostic (9.40e-2)" "unprognostic (3.59e-2)" "unprognostic (1.25e-1)" "unprognostic (9.81e-3)" "unprognostic (6.94e-2)" "unprognostic (2.44e-2)" "unprognostic (4.03e-1)" "unprognostic (2.67e-2)" "unprognostic (3.13e-3)" "unprognostic (4.22e-1)" "unprognostic (9.20e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-1)" "unprognostic (3.15e-2)" "unprognostic (1.25e-3)" 0.1 0.1 0.2 0.4 0.3 2.9 0.4 1.2 0.4 0.2 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.3 0.2 0.2 0.1 0.0 0.1 0.2 0.5 0.5 0.2 0.1 0.1 0.1 0.1 0.0 0.5 0.7 0.5 0.6 0.5 0.0 0.3 0.2 0.0 0.1 0.3 0.3 0.4 9.8 0.3 0.2 0.1 0.0 0.5 0.2 0.0 0.6 0.0 0.2 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.2 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.9 0.0 0.0 2.9 0.1 0.0 0.2 0.3 1.2 0.4 0.2 0.1 0.5 0.2 0.5 0.3 0.3 0.6 0.0 0.0 3.1 0.3 0.4 0.0 0.4 1.0 0.0 4.1 0.8 0.4 0.4 0.0 1.8 0.0 0.0 0.1 16.1 0.3 0.0 0.1 266.3 0.5 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 1.0 0.0 0.0 0.4 1.2 2.0 0.3 0.0 122.0 2.1 0.4 0.0 0.0 0.2 1.9 0.0 1.0 0.7 0.2 1.6 0.7 0.3 1.3 0.0 0.1 2.7 5.5 0.0 0.1 0.2 6.0 1.4 0.0 0.0 0.0 0.0 0.1 0.2 1.3 FAM234B KIAA1467 ENSG00000084444 "Family with sequence similarity 234 member B" A2RU67 12 13044381-13142521 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 22.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.8;Breast glandular cells: 16.8;Collecting duct cells: 18.4;Erythroid cells: 13.2;Spermatogonia: 13.7" "Cancer enhanced" "Detected in all" "breast cancer: 16.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010803, HPA010850" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "HPA010803: AB_1079200, HPA010850: AB_2732402" "unprognostic (1.85e-3)" "unprognostic (1.99e-1)" "unprognostic (1.93e-3)" "unprognostic (2.92e-2)" "unprognostic (1.29e-1)" "unprognostic (8.03e-3)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (9.55e-2)" "unprognostic (3.40e-2)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "unprognostic (1.85e-3)" "unprognostic (5.22e-2)" "unprognostic (1.06e-1)" "unprognostic (4.06e-3)" "unprognostic (7.62e-2)" 3.3 2.5 14.1 1.6 14.7 3.0 16.4 9.2 22.9 2.3 4.5 1.5 1.8 2.5 3.1 2.0 2.9 1.6 1.8 15.5 16.1 5.4 2.2 2.7 1.6 10.5 10.7 2.5 2.6 3.3 5.1 5.7 11.5 6.2 1.1 17.6 2.7 2.4 2.2 12.7 1.8 2.3 8.1 2.2 1.6 5.6 11.7 2.3 8.6 1.7 1.5 2.5 2.6 13.4 3.6 3.6 10.9 7.7 8.3 8.0 8.4 2.4 2.8 5.3 10.4 3.8 5.3 14.7 2.9 2.9 9.4 5.4 13.9 2.6 11.0 1.7 7.7 8.7 4.1 3.0 4.4 7.6 4.7 6.3 5.5 7.8 5.9 8.0 7.2 10.2 2.2 5.1 5.8 12.2 6.5 4.8 14.3 2.8 2.0 8.5 14.0 1.6 3.3 8.9 15.0 4.9 5.3 3.5 4.3 18.5 4.4 4.2 3.5 3.5 5.8 6.5 2.6 2.8 3.9 9.4 11.1 3.4 4.4 0.2 1.4 1.1 1.3 2.6 1.8 2.4 1.5 1.3 1.2 3.4 2.1 2.3 0.3 1.5 4.2 2.3 1.2 0.7 14.1 14.7 9.2 22.9 15.5 16.1 10.5 10.7 11.5 8.1 11.7 13.4 5.4 3.2 3.3 0.0 2.2 0.0 2.1 0.0 1.2 29.8 16.8 3.6 0.0 2.8 0.0 18.4 2.1 9.6 1.0 0.0 1.9 2.0 9.3 1.1 1.0 3.2 12.2 13.2 0.0 1.3 3.4 1.9 0.5 1.5 0.0 2.0 5.0 2.3 3.6 3.3 0.0 0.8 0.0 1.6 0.0 3.6 5.6 1.5 0.0 0.0 2.3 4.2 1.0 0.0 0.0 1.1 1.2 5.3 1.9 3.3 2.6 1.2 0.0 3.3 0.0 1.6 1.3 9.2 13.7 2.2 0.0 3.6 1.3 1.2 0.9 1.5 FAM25A bA96C23.5 ENSG00000188100 "Family with sequence similarity 25 member A" B3EWG3 10 87020294-87024730 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 143.3;esophagus: 519.5;salivary gland: 140.0;skin 1: 175.0;vagina: 193.1" "Group enriched" "Detected in some" 4 "Suprabasal keratinocytes: 49.6;Syncytiotrophoblasts: 16.1" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 53.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A-431: 30.3;SK-BR-3: 70.0" "Low region specificity" "Detected in single" HPA044808 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA044808: AB_2679096" "unprognostic (9.94e-2)" "unprognostic (2.57e-1)" "unprognostic (7.62e-2)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (1.05e-5)" "unprognostic (1.21e-1)" 0.3 2.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 143.3 0.0 0.1 0.0 0.1 0.0 519.5 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.1 1.5 0.0 0.1 0.0 0.0 140.0 0.0 1.2 175.0 0.0 0.0 0.0 0.1 0.5 0.1 0.1 1.4 0.0 0.0 63.6 0.1 193.1 0.1 30.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.3 0.0 0.0 0.2 0.0 0.0 9.0 0.1 0.0 0.0 0.2 2.0 0.0 0.3 0.0 1.6 1.2 0.0 0.0 0.0 70.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.9 0.1 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.8 2.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 49.6 16.1 0.0 0.0 0.0 1.9 FAM81A MGC26690 ENSG00000157470 "Family with sequence similarity 81 member A" Q8TBF8 15 59372693-59523555 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.0" "Group enriched" "Detected in many" 5 "Collecting duct cells: 31.3;Excitatory neurons: 83.0;Inhibitory neurons: 67.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.1;plasmacytoid DC: 11.7" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.7" "Cell line enriched" "Detected in many" 4 "Daudi: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001847, HPA065797" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA001847: AB_2666462, HPA065797: AB_2685560" "unprognostic (3.43e-3)" "unprognostic (4.47e-3)" "unprognostic (1.93e-1)" "unprognostic (1.32e-3)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (1.43e-1)" "unprognostic (2.39e-1)" "unprognostic (8.90e-2)" "unprognostic (4.68e-2)" "unprognostic (2.13e-1)" "unprognostic (9.95e-3)" "unprognostic (1.08e-2)" "unprognostic (6.53e-2)" "unprognostic (3.76e-1)" "unprognostic (7.80e-2)" 0.4 0.1 7.0 2.4 10.5 0.2 1.4 0.0 17.0 6.7 0.5 4.3 2.4 2.4 4.4 0.4 6.1 1.6 1.5 11.0 3.2 6.8 0.4 0.7 4.9 0.0 0.1 0.6 1.9 1.1 2.6 0.8 0.1 2.3 5.2 1.3 2.6 1.5 0.5 0.9 1.4 1.2 0.0 1.4 2.4 1.8 6.0 0.4 2.1 2.8 5.5 0.4 0.4 8.3 10.5 15.0 1.1 0.2 0.4 0.2 6.0 0.6 0.0 1.0 2.8 1.8 1.7 66.5 0.3 0.2 14.1 7.8 8.3 2.5 1.9 0.7 4.3 0.0 10.6 0.8 0.0 5.7 1.3 0.0 1.5 0.4 0.8 0.8 0.1 2.7 0.1 0.0 1.0 3.5 0.1 0.1 0.9 2.7 5.4 1.5 14.8 1.7 3.3 3.8 3.0 0.8 6.0 0.3 9.9 0.6 2.5 3.4 0.3 2.4 7.4 2.9 11.4 0.1 0.0 0.8 2.5 2.2 6.7 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 5.1 2.3 0.0 0.0 0.3 0.1 0.0 11.7 0.0 0.3 7.0 10.5 0.0 17.0 11.0 3.2 0.0 0.1 0.1 0.0 6.0 8.3 0.2 0.0 1.3 11.4 2.5 0.5 1.4 0.2 0.6 0.0 2.4 2.4 6.9 0.0 1.0 31.3 0.0 0.1 0.0 1.7 5.9 0.5 0.5 11.2 0.9 0.7 1.2 1.3 83.0 0.2 1.6 0.6 1.1 1.5 1.3 0.2 0.4 0.2 1.3 10.1 67.0 1.9 2.0 0.6 1.5 1.4 0.3 0.7 8.8 4.7 0.7 1.1 0.0 2.5 8.1 0.4 1.9 0.0 1.2 1.4 0.8 0.3 8.4 0.2 0.0 1.1 3.1 0.2 1.6 1.5 0.4 0.0 0.4 0.2 4.0 1.0 FAM83B "C6orf143, FLJ30642" ENSG00000168143 "Family with sequence similarity 83 member B" Q5T0W9 6 54846771-54945099 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 14.5;skin 1: 25.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.8;Basal prostatic cells: 32.5;Basal squamous epithelial cells: 43.3;Squamous epithelial cells: 31.9;Suprabasal keratinocytes: 41.1;Urothelial cells: 25.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 15.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.3;HaCaT: 18.1;HBEC3-KT: 9.8;hTCEpi: 19.7;hTERT-HME1: 23.8;RT4: 19.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031464, HPA031465" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "HPA031464: AB_10599973, HPA031465: AB_10601566" "unprognostic (2.29e-1)" "unprognostic (3.93e-2)" "unprognostic (3.71e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (7.27e-2)" "unprognostic (5.77e-3)" "prognostic unfavorable (7.60e-4)" "unprognostic (1.62e-1)" "unprognostic (3.19e-2)" "unprognostic (1.85e-1)" "unprognostic (4.35e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.86e-5)" 0.0 0.0 0.1 1.0 0.1 0.1 2.2 0.1 0.1 3.8 0.0 8.0 7.4 0.3 1.2 14.5 1.6 2.1 1.1 0.0 0.0 2.5 0.1 0.1 0.0 0.0 0.7 0.0 1.5 0.0 0.0 4.3 0.1 1.8 8.2 0.1 4.7 1.1 0.7 25.9 7.4 0.2 0.0 0.0 3.9 0.6 0.0 2.3 3.6 0.1 3.6 4.3 9.8 0.2 13.3 0.2 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 6.5 3.6 0.0 0.0 0.0 0.1 18.1 0.0 9.8 0.1 0.0 2.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 19.7 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.6 4.1 0.0 0.0 0.0 0.0 9.1 19.2 0.2 0.0 2.9 0.6 0.0 3.3 4.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 33.8 32.5 6.6 43.3 0.0 1.5 3.0 3.1 5.7 6.5 7.3 0.0 11.2 0.1 9.0 0.0 6.1 6.3 8.8 0.8 0.3 1.2 0.0 0.2 3.5 11.9 0.4 9.2 8.1 0.0 0.0 0.4 0.0 0.6 0.0 0.1 5.4 6.1 0.0 1.5 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 17.4 0.0 0.1 9.1 12.6 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.6 31.9 41.1 18.7 0.1 0.0 8.8 25.4 FAM83C "C20orf128, dJ614O4.7" ENSG00000125998 "Family with sequence similarity 83 member C" Q9BQN1 20 35285731-35292425 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 33.3;skin 1: 42.3;vagina: 15.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 27.9;Basal squamous epithelial cells: 17.6;Early spermatids: 11.8;Squamous epithelial cells: 26.1;Suprabasal keratinocytes: 64.2" "Cancer enhanced" "Detected in some" "cervical cancer: 9.9;head and neck cancer: 18.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034227, HPA049978" Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB034227: AB_1562876, HPA049978: AB_2680979" "unprognostic (3.76e-2)" "unprognostic (2.88e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (3.61e-1)" "unprognostic (1.57e-1)" "unprognostic (4.38e-2)" "unprognostic (3.11e-1)" "unprognostic (9.17e-5)" "unprognostic (9.89e-3)" "unprognostic (1.71e-1)" "unprognostic (5.01e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.9 0.0 0.2 5.3 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 4.2 0.0 0.1 42.3 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 2.1 0.6 15.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 27.9 1.1 0.0 17.6 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 11.8 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.2 6.5 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.3 1.3 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 26.1 64.2 0.0 0.0 0.0 0.1 1.9 FAM83E FLJ20200 ENSG00000105523 "Family with sequence similarity 83 member E" Q2M2I3 19 48599961-48615076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;salivary gland: 28.5;stomach 1: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 22.8;Early spermatids: 26.0;Gastric mucus-secreting cells: 74.9;Intestinal goblet cells: 26.9;Paneth cells: 16.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "CAPAN-2: 2.9;OE19: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049305, HPA075968" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol Vesicles "HPA049305: AB_2680705, HPA075968: " "unprognostic (1.36e-1)" "unprognostic (9.81e-3)" "unprognostic (3.83e-2)" "unprognostic (7.39e-2)" "unprognostic (4.77e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (2.26e-2)" "unprognostic (3.18e-1)" "unprognostic (2.71e-1)" "unprognostic (8.00e-2)" "unprognostic (9.31e-2)" "unprognostic (7.05e-8)" "unprognostic (5.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.70e-1)" "unprognostic (8.90e-3)" 0.1 0.1 0.2 3.7 0.3 0.4 1.4 0.8 0.5 10.6 0.2 32.7 30.0 1.1 0.1 7.0 3.9 6.4 0.2 0.3 0.2 0.8 0.3 8.0 0.2 0.1 0.1 0.0 1.2 0.0 0.2 0.6 0.2 3.2 16.6 0.2 28.5 0.4 2.7 1.9 30.0 1.0 0.0 0.2 37.4 2.2 0.2 0.1 0.1 0.0 1.3 1.2 4.1 0.5 0.4 0.4 0.0 0.7 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 2.9 0.5 0.2 0.1 0.0 0.5 0.1 0.0 0.0 0.4 0.1 0.1 0.3 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.8 1.1 9.4 0.9 0.2 0.1 0.3 0.0 0.2 0.5 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.2 0.5 0.1 0.1 0.2 0.1 1.0 0.1 0.2 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.2 0.6 0.1 0.1 0.1 0.0 0.0 0.2 0.3 0.8 0.5 0.3 0.2 0.1 0.1 0.2 0.0 0.2 0.5 0.0 9.6 13.4 1.3 0.4 0.0 1.4 0.8 0.6 0.0 1.8 0.8 2.1 8.6 6.5 1.8 0.0 0.1 0.3 22.8 0.0 0.1 26.0 4.8 0.5 0.2 5.4 0.0 0.3 1.1 0.1 0.2 74.9 5.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 26.9 2.0 0.0 0.0 9.3 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 1.6 16.5 0.0 0.4 3.3 12.7 0.0 5.1 0.0 0.0 0.2 0.2 0.8 0.5 2.3 0.0 0.1 0.3 0.1 12.8 6.9 FAM83F ENSG00000133477 "Family with sequence similarity 83 member F" Q8NEG4 22 39994954-40043534 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.3;testis: 40.8" "Cell type enhanced" "Detected in many" "Late spermatids: 68.1;Proximal enterocytes: 39.9;Suprabasal keratinocytes: 34.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 12.1;HaCaT: 12.8;HBEC3-KT: 15.5;hTCEpi: 37.9;hTERT-HME1: 11.8;OE19: 17.6;RT4: 18.6;SCLC-21H: 39.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051207, HPA064657" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA051207: AB_2681388, HPA064657: AB_2685313" "unprognostic (2.78e-2)" "unprognostic (3.91e-2)" "prognostic favorable (1.73e-4)" "unprognostic (5.36e-2)" "unprognostic (1.48e-5)" "unprognostic (1.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (4.79e-1)" "unprognostic (2.48e-1)" "prognostic favorable (9.40e-4)" "unprognostic (3.25e-1)" "unprognostic (1.10e-7)" "unprognostic (2.93e-1)" "unprognostic (2.37e-1)" "unprognostic (2.98e-2)" "unprognostic (8.32e-2)" 1.2 0.1 0.2 0.5 0.1 1.2 4.7 0.3 0.2 2.6 0.1 5.3 3.2 0.2 2.5 20.3 1.2 0.5 2.0 0.2 0.1 4.0 2.9 0.2 0.0 0.1 0.1 0.3 13.5 5.4 1.2 0.1 0.1 9.0 3.2 0.4 8.2 6.6 0.1 18.8 7.6 0.1 0.0 0.0 6.8 40.8 0.3 0.9 5.9 0.2 1.1 2.6 7.0 0.3 8.3 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 12.1 2.3 0.0 0.0 0.0 0.0 12.8 0.0 15.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 37.9 0.0 11.8 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.1 2.1 17.6 0.0 0.0 0.0 0.1 0.3 18.6 39.8 0.0 0.3 3.4 0.0 1.3 2.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.3 1.1 0.0 0.0 0.0 0.5 28.7 14.5 18.0 23.9 1.2 19.1 10.4 5.2 12.8 7.4 23.9 0.0 0.2 0.0 33.1 3.9 9.6 28.4 6.2 0.5 1.0 13.1 0.4 0.2 15.1 0.2 1.0 10.7 6.5 1.3 0.2 0.0 2.2 0.2 0.0 0.2 21.0 14.2 0.6 2.9 68.1 1.8 0.5 1.8 0.0 0.0 0.9 0.0 0.5 0.1 12.5 21.6 2.2 0.2 16.3 39.9 5.9 6.4 0.6 0.0 1.1 1.3 12.4 1.8 30.6 34.5 1.4 0.8 0.4 15.6 17.8 FAM83G "FLJ41564, PAWS1" ENSG00000188522 "Family with sequence similarity 83 member G" A6ND36 17 18968789-19004764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.3;skin 1: 67.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 77.8;Basal squamous epithelial cells: 39.3;Distal enterocytes: 46.5;Squamous epithelial cells: 55.3;Suprabasal keratinocytes: 68.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA023369, HPA023940" Enhanced Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA023369: AB_1848415, HPA023940: AB_1848416" "unprognostic (2.12e-2)" "unprognostic (5.90e-2)" "unprognostic (1.17e-1)" "unprognostic (9.48e-2)" "unprognostic (1.42e-3)" "unprognostic (2.04e-2)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.07e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-2)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (5.65e-2)" "prognostic favorable (7.58e-6)" "unprognostic (9.68e-2)" "unprognostic (5.13e-2)" "unprognostic (3.74e-2)" 2.3 2.2 0.8 2.9 0.8 1.4 2.8 0.8 1.2 10.8 2.1 8.2 10.8 2.5 0.9 51.3 1.6 6.4 17.2 0.8 1.9 7.1 21.7 3.2 3.0 1.6 1.4 1.4 9.5 6.4 4.3 0.7 2.7 3.5 5.3 0.2 10.9 2.2 6.9 67.3 11.3 1.5 0.9 2.0 9.8 1.0 1.4 3.7 5.6 0.8 5.7 2.5 17.0 0.7 24.7 22.4 0.2 0.0 0.7 2.0 35.9 25.2 11.0 21.0 15.7 28.7 8.8 16.1 15.1 16.7 17.1 28.6 3.6 21.1 9.6 13.2 8.1 0.4 11.2 15.9 15.3 2.9 7.9 2.8 38.9 13.6 22.3 7.9 7.6 2.5 7.7 0.5 6.0 15.0 0.7 6.0 11.0 34.1 0.1 0.1 0.0 7.8 10.1 6.2 11.2 0.0 8.7 5.3 1.5 29.1 9.2 3.6 14.2 12.9 21.6 6.1 29.8 2.2 4.0 4.1 10.1 0.1 8.6 1.1 0.0 0.0 0.7 0.0 0.3 0.3 0.4 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.8 0.8 0.8 1.2 0.8 1.9 1.6 1.4 2.7 0.9 1.4 0.7 0.6 3.2 2.2 0.0 2.5 77.8 12.2 9.9 39.3 0.2 7.1 2.9 5.1 11.5 6.3 7.3 0.0 0.4 0.7 46.5 0.0 15.8 0.1 2.4 1.0 1.9 7.1 2.7 0.1 10.0 9.7 2.6 17.3 5.0 8.9 3.5 1.1 20.9 1.2 0.0 0.1 17.7 8.2 0.3 7.8 1.9 0.0 1.0 5.4 0.0 1.0 0.2 3.1 0.5 0.0 24.3 22.8 0.0 3.0 13.2 15.3 4.4 2.5 0.4 0.0 1.3 2.0 0.1 1.0 55.3 68.5 1.9 2.6 0.0 17.1 9.1 FAM98C FLJ44669 ENSG00000130244 "Family with sequence similarity 98 member C" Q17RN3 19 38403135-38409088 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 100.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040930, HPA041730" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 26: Non-specific - Mitochondria" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli" Cytosol "HPA040930: AB_10795484, HPA041730: AB_10804114" "unprognostic (3.01e-2)" "unprognostic (6.44e-3)" "unprognostic (5.15e-2)" "unprognostic (1.94e-1)" "unprognostic (3.18e-1)" "unprognostic (8.10e-3)" "unprognostic (3.06e-1)" "unprognostic (2.15e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (8.51e-5)" "unprognostic (2.82e-2)" "unprognostic (8.91e-3)" "unprognostic (1.01e-1)" "unprognostic (2.37e-3)" "unprognostic (2.43e-1)" "unprognostic (2.96e-1)" "prognostic favorable (5.53e-4)" 10.6 9.6 14.5 5.5 13.9 8.7 12.3 12.3 17.6 14.8 7.2 14.6 13.8 10.7 2.6 17.7 12.3 5.3 11.6 13.8 11.7 12.2 13.3 9.1 6.2 18.9 11.6 12.5 18.6 8.4 11.6 2.3 13.5 13.4 4.7 1.7 13.9 5.8 3.3 25.2 15.4 3.3 12.7 11.8 14.4 9.0 14.4 4.7 11.4 2.5 3.8 12.7 14.6 14.3 15.6 16.3 1.9 9.4 2.0 6.8 8.2 8.8 7.3 8.5 8.9 2.8 11.0 13.9 9.7 5.2 3.0 7.5 3.7 6.3 1.4 22.6 7.6 4.6 2.9 6.5 9.0 3.9 8.1 6.6 13.0 4.3 7.8 4.7 5.0 22.5 12.9 15.0 5.1 17.2 5.9 3.1 1.4 25.5 17.5 11.6 3.9 8.4 10.4 8.0 3.3 9.6 8.8 15.6 5.6 0.9 11.8 12.3 6.7 3.8 10.4 11.9 10.7 16.1 8.8 6.1 9.9 9.2 6.2 0.0 1.9 10.8 2.4 2.7 3.2 2.0 4.2 3.4 2.6 6.5 3.3 2.6 1.7 3.0 2.7 1.0 3.9 1.4 14.5 13.9 12.3 17.6 13.8 11.7 18.9 11.6 13.5 12.7 14.4 14.3 19.8 9.6 8.9 3.6 17.5 21.5 22.3 23.7 14.8 15.1 21.1 26.3 5.4 10.0 21.2 23.9 12.5 11.8 22.1 41.4 21.5 22.2 6.4 18.2 9.1 12.0 25.7 9.7 11.7 32.9 10.9 13.9 17.9 18.0 15.2 8.6 11.4 12.5 11.0 11.8 9.5 32.4 22.4 13.2 18.2 2.4 18.6 14.3 23.2 2.8 14.4 14.6 34.0 5.5 8.5 23.8 42.8 18.4 12.7 12.2 100.4 22.6 22.4 12.5 13.1 13.5 13.8 37.4 37.4 22.3 29.8 6.2 21.8 12.9 34.8 23.4 FANCA "FA-H, FAA, FACA, FAH, FANCH" ENSG00000187741 "FA complementation group A" O15360 16 89737549-89816657 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.2;testis: 21.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 44.1;Spermatogonia: 38.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063236 Supported Nucleoplasm NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA063236: AB_2684966" "unprognostic (5.99e-2)" "unprognostic (5.68e-2)" "unprognostic (2.36e-1)" "unprognostic (5.12e-2)" "unprognostic (1.87e-1)" "unprognostic (7.11e-2)" "unprognostic (1.45e-4)" "unprognostic (9.21e-2)" "unprognostic (1.58e-2)" "unprognostic (2.05e-1)" "unprognostic (4.82e-3)" "unprognostic (8.48e-4)" "unprognostic (7.82e-10)" "unprognostic (3.67e-2)" "unprognostic (2.05e-1)" "unprognostic (2.94e-1)" "unprognostic (1.62e-1)" 1.4 1.9 1.7 6.7 1.9 20.2 1.9 2.4 3.3 2.1 1.5 5.5 5.2 1.2 0.8 6.6 2.0 1.2 1.6 1.8 1.2 2.9 6.1 3.4 12.5 1.4 1.1 1.4 1.9 1.4 1.9 4.1 1.5 1.7 6.2 1.0 2.1 0.6 0.7 5.2 5.6 2.1 1.1 6.7 3.6 21.6 1.5 8.1 1.7 0.6 13.5 2.2 2.7 1.9 23.2 34.8 40.8 35.7 2.6 5.2 31.2 28.2 15.3 46.5 19.5 30.6 37.3 56.2 12.9 9.8 15.5 34.7 27.7 21.1 48.8 13.4 46.5 16.6 49.1 63.4 1.7 17.1 17.5 1.7 2.2 37.8 12.0 6.6 14.9 28.0 40.9 16.9 24.6 53.6 34.6 73.7 26.5 31.5 21.3 61.4 32.8 10.3 11.8 21.5 36.3 19.7 41.9 12.3 5.4 23.3 22.4 30.4 11.1 37.0 38.9 20.9 30.0 15.1 19.0 56.3 17.5 37.8 36.1 2.5 7.4 9.9 4.2 8.5 3.0 7.0 2.4 3.7 6.2 4.6 0.6 2.6 9.4 8.2 9.2 0.4 9.2 4.2 1.7 1.9 2.4 3.3 1.8 1.2 1.4 1.1 1.5 1.1 1.5 1.9 1.5 0.0 1.1 0.7 9.6 3.4 1.6 2.6 0.0 8.1 3.0 2.0 2.9 0.0 3.5 16.5 10.4 16.0 12.3 5.1 1.9 2.0 5.9 2.8 3.5 2.1 1.8 20.8 10.0 1.6 9.9 3.3 9.2 3.4 2.5 19.0 5.3 4.7 8.8 3.3 5.7 8.1 2.0 4.1 3.1 4.1 1.5 6.8 0.0 1.0 3.0 1.1 21.6 3.0 1.7 1.9 1.7 0.0 21.1 1.3 6.6 10.4 6.4 7.7 0.0 2.7 3.5 44.1 38.5 3.8 1.8 25.3 9.3 6.8 11.4 2.6 FANCB "FAAP95, FAB, FLJ34064" ENSG00000181544 "FA complementation group B" Q8NB91 X 14835961-14873069 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.4;brain: 3.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 12.4;Oligodendrocytes: 33.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003124 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA003124: AB_1078813" "unprognostic (3.49e-2)" "unprognostic (1.92e-3)" "unprognostic (1.16e-2)" "unprognostic (8.42e-3)" "unprognostic (7.99e-2)" "unprognostic (2.42e-2)" "unprognostic (4.05e-5)" "unprognostic (6.93e-3)" "unprognostic (1.77e-3)" "unprognostic (7.70e-3)" "unprognostic (2.76e-4)" "unprognostic (1.03e-1)" "unprognostic (1.25e-11)" "unprognostic (4.46e-2)" "unprognostic (1.92e-1)" "unprognostic (6.88e-2)" "unprognostic (5.96e-2)" 0.2 0.1 2.1 0.7 3.3 3.4 0.5 1.2 1.6 0.3 0.0 0.3 0.2 0.3 0.1 0.4 0.2 0.1 0.1 0.8 1.0 0.1 0.1 0.2 1.2 1.7 2.2 0.4 0.1 0.1 0.0 0.8 1.8 0.2 0.5 0.0 0.2 0.1 0.1 0.3 0.2 0.3 1.5 0.4 0.2 0.2 3.1 1.4 0.2 0.1 1.3 0.3 0.3 3.8 7.3 5.0 4.8 3.9 0.3 1.1 1.7 11.2 3.0 8.8 9.9 3.5 5.3 10.6 1.9 4.4 6.6 7.0 11.3 4.1 15.0 5.1 5.9 4.1 7.9 1.7 0.1 5.8 3.3 0.1 0.4 9.0 2.0 0.9 4.4 3.5 7.3 7.2 5.2 3.5 5.7 3.2 6.1 3.0 7.1 5.1 11.4 5.2 0.8 2.6 3.1 3.5 5.7 2.4 3.2 11.2 3.6 2.0 1.8 6.7 3.7 14.5 6.8 1.8 3.9 7.2 3.0 4.1 14.3 0.3 0.2 0.2 0.2 0.1 0.1 0.7 0.1 0.3 0.2 0.5 0.1 0.1 0.4 0.4 0.1 0.2 0.4 0.2 2.1 3.3 1.2 1.6 0.8 1.0 1.7 2.2 1.8 1.5 3.1 3.8 1.9 3.2 0.5 1.0 5.2 1.7 1.1 1.5 0.6 3.0 1.6 3.3 0.4 0.0 1.8 0.0 0.0 7.0 6.2 0.9 0.0 1.2 0.4 2.1 2.7 1.9 0.0 5.0 6.3 1.5 12.4 2.0 1.5 2.3 3.8 6.6 1.4 0.3 3.6 3.3 4.8 0.8 4.1 0.3 1.8 0.6 1.2 2.7 0.0 2.8 1.0 0.4 3.1 3.0 33.1 0.7 0.1 1.2 6.5 0.7 0.2 0.4 1.2 0.5 0.0 2.4 2.3 5.2 4.2 3.8 1.0 3.8 4.1 0.7 1.8 1.5 FANCE "FACE, FAE" ENSG00000112039 "FA complementation group E" Q9HB96 6 35452338-35467102 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 22.1;Extravillous trophoblasts: 104.8;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB014893 Enhanced Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 32: U-937 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB014893: " "unprognostic (2.66e-1)" "unprognostic (8.01e-3)" "unprognostic (7.73e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.80e-3)" "prognostic unfavorable (2.08e-9)" "unprognostic (8.90e-2)" "unprognostic (5.70e-3)" "unprognostic (8.41e-2)" "unprognostic (1.52e-1)" "unprognostic (2.91e-2)" "unprognostic (1.28e-1)" "unprognostic (1.70e-1)" "unprognostic (3.05e-1)" "unprognostic (2.44e-2)" "unprognostic (5.14e-2)" 4.6 1.5 2.6 3.2 2.5 5.8 5.0 2.8 3.1 7.1 2.0 3.1 2.1 3.7 3.4 8.6 4.8 1.5 3.3 2.3 2.9 2.1 1.3 4.1 4.5 2.7 2.6 7.8 3.5 4.0 3.1 9.3 2.6 3.8 3.0 1.8 4.3 2.7 11.0 13.8 3.5 3.1 2.4 3.8 3.4 8.7 2.7 2.6 3.0 3.1 5.7 4.0 7.7 2.7 9.9 4.2 12.8 27.6 9.2 15.9 34.6 11.4 9.6 14.8 12.1 11.1 5.3 33.0 7.5 6.7 11.2 7.2 13.7 9.8 13.9 11.0 11.9 23.8 11.7 6.8 4.8 12.6 8.2 10.1 28.6 17.7 27.7 3.9 8.7 12.6 21.3 11.6 12.2 11.4 5.8 16.6 4.7 10.6 7.0 18.8 12.3 12.1 3.1 10.0 12.1 11.4 6.4 9.1 10.0 11.9 8.8 43.7 5.6 16.7 14.5 10.9 18.1 7.4 29.3 11.6 3.9 24.3 16.8 0.0 0.2 0.2 0.4 0.1 0.7 0.1 0.6 0.9 0.1 0.5 0.3 0.3 0.0 0.5 0.1 0.4 0.3 0.2 2.6 2.5 2.8 3.1 2.3 2.9 2.7 2.6 2.6 2.4 2.7 2.7 7.0 6.4 0.0 1.0 2.4 8.8 4.1 4.7 1.8 1.1 2.0 2.8 2.7 0.0 1.6 0.0 0.0 22.1 2.0 1.6 0.0 1.7 0.3 1.9 2.4 3.7 1.2 2.5 0.4 0.8 104.8 2.8 1.1 3.4 0.0 5.2 1.4 0.7 6.0 0.0 0.9 3.6 0.0 0.8 1.3 0.6 1.5 1.4 1.8 2.8 0.5 1.9 1.0 0.5 1.0 1.1 0.4 0.7 3.1 5.8 1.1 0.3 0.1 2.0 0.0 4.0 3.4 8.2 13.2 4.6 7.1 46.7 2.2 3.4 4.4 3.5 FANCI "FLJ10719, KIAA1794" ENSG00000140525 "FA complementation group I" Q9NVI1 15 89243945-89317261 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.4;lymphoid tissue: 44.2;testis: 32.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.6;Spermatocytes: 69.5;Spermatogonia: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 23.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039972, HPA040379" Approved Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039972: AB_10673265, HPA040379: AB_2676951" "unprognostic (6.88e-2)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (2.99e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.82e-3)" "unprognostic (1.15e-2)" "unprognostic (4.59e-3)" "prognostic unfavorable (3.59e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.71e-13)" "unprognostic (2.40e-2)" "unprognostic (2.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-1)" 3.2 2.1 1.6 13.0 1.3 31.4 6.0 3.8 2.5 3.3 0.0 10.5 6.0 4.7 1.1 8.1 3.4 3.0 1.7 1.7 0.7 1.7 2.9 3.4 23.9 1.2 0.9 3.8 3.0 3.0 0.6 11.3 1.7 3.6 12.4 5.4 2.8 2.0 0.8 8.0 7.3 6.9 0.6 6.0 6.7 32.6 1.3 44.2 2.0 0.8 26.6 5.4 3.7 1.7 108.2 122.4 127.8 86.1 10.8 16.0 78.5 101.4 58.3 123.6 150.5 96.8 95.4 198.8 53.4 33.8 79.3 143.9 196.8 69.0 116.2 127.8 123.5 197.2 176.7 45.8 1.7 146.0 96.3 8.6 6.8 87.1 44.4 17.6 51.7 120.2 139.2 142.3 83.5 61.5 150.9 49.6 101.1 70.3 44.5 130.6 187.1 84.6 28.5 196.8 93.9 80.8 105.2 73.3 46.7 85.7 81.2 64.8 35.4 103.2 103.8 94.9 155.8 93.3 209.5 151.9 38.5 125.7 104.7 23.4 2.3 3.0 4.7 3.0 2.8 3.5 4.7 6.5 2.2 3.6 3.3 5.6 3.1 5.1 4.3 4.1 11.8 3.1 1.6 1.3 3.8 2.5 1.7 0.7 1.2 0.9 1.7 0.6 1.3 1.7 2.6 3.2 1.5 3.6 3.8 4.2 2.6 4.0 0.6 2.4 2.9 2.7 3.9 0.0 3.3 1.8 0.0 17.0 3.9 4.2 0.0 2.0 7.9 5.0 3.7 3.0 1.2 48.6 7.0 2.9 18.3 3.9 5.6 4.5 2.5 14.9 6.8 0.8 8.1 1.7 5.8 5.9 0.0 3.0 3.8 7.9 3.4 4.8 1.8 1.9 3.3 11.6 1.0 9.0 6.9 2.5 1.2 1.5 13.9 2.0 1.3 1.0 6.3 1.9 6.6 3.6 4.0 69.5 60.2 9.2 2.4 12.4 8.1 2.5 9.1 2.8 FAR1 "FLJ22728, MLSTD2, SDR10E1" ENSG00000197601 "Fatty acyl-CoA reductase 1" Q8WVX9 11 13668668-13732346 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Cataract, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 437.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017322 Approved Supported Peroxisomes NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 15: RT4 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Peroxisomes "HPA017322: AB_1848424" "unprognostic (3.96e-2)" "unprognostic (1.92e-1)" "prognostic favorable (2.27e-4)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (4.62e-2)" "unprognostic (3.66e-1)" "unprognostic (3.30e-1)" "unprognostic (2.79e-1)" "unprognostic (3.60e-2)" "unprognostic (2.59e-2)" "unprognostic (1.84e-2)" "unprognostic (2.97e-2)" "unprognostic (2.52e-1)" "unprognostic (2.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-3)" 21.1 16.2 19.3 23.0 36.0 74.9 20.6 34.3 31.5 23.8 24.5 32.9 38.7 24.7 24.9 50.9 17.7 13.7 20.0 22.6 29.7 14.0 5.0 20.2 20.5 48.4 29.9 19.9 21.3 29.1 15.6 24.6 44.1 20.5 37.6 32.6 18.2 15.4 15.2 12.2 21.1 30.7 37.3 20.5 62.0 20.8 32.1 16.5 19.8 18.6 23.9 28.4 30.0 94.8 79.5 50.6 49.1 38.4 45.9 52.6 26.7 69.2 27.6 50.0 52.7 53.5 66.4 100.9 30.2 55.5 74.3 84.3 73.2 69.9 76.1 30.0 59.4 43.4 44.8 0.2 44.1 87.9 33.7 40.2 70.3 36.2 107.7 36.9 49.6 50.2 68.9 29.3 41.5 39.9 65.5 26.3 25.8 100.1 72.6 56.9 62.6 28.4 48.4 126.4 37.7 27.3 65.5 61.6 34.4 56.2 37.8 54.1 62.1 68.5 58.2 63.7 58.4 16.4 59.6 84.7 43.4 26.4 42.4 10.4 24.9 28.0 7.7 21.3 5.4 3.5 3.7 6.6 28.5 5.5 3.3 5.5 38.9 9.1 18.2 4.4 5.3 7.7 19.3 36.0 34.3 31.5 22.6 29.7 48.4 29.9 44.1 37.3 32.1 94.8 38.6 35.3 21.1 80.0 24.2 32.2 24.2 21.5 41.5 46.0 27.6 20.3 24.1 5.7 26.2 22.0 41.7 25.7 40.2 59.8 5.9 12.8 100.8 21.1 36.5 31.4 36.0 38.5 146.0 25.9 18.5 26.8 114.7 26.2 38.7 23.3 29.6 2.5 33.9 47.1 113.5 28.8 26.4 53.5 57.0 181.3 26.8 48.8 35.6 71.2 54.8 20.6 20.6 93.5 437.2 29.3 43.4 25.6 36.1 30.8 23.3 8.7 18.7 50.4 26.3 29.3 29.3 41.6 32.3 116.9 19.9 9.9 25.8 17.0 47.7 42.0 FAR2 "FLJ10462, MLSTD1, SDR10E2" ENSG00000064763 "Fatty acyl-CoA reductase 2" Q96K12 12 29149103-29340980 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.2;intestine: 34.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 114.3;Inhibitory neurons: 172.1;Microglial cells: 63.7;Syncytiotrophoblasts: 193.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 50.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 76.2;HUVEC TERT2: 84.0;NB-4: 74.2;SK-BR-3: 89.6;TIME: 68.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015884 Approved Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoli "HPA015884: AB_1853998" "unprognostic (6.32e-2)" "unprognostic (2.40e-2)" "unprognostic (1.50e-3)" "unprognostic (3.33e-3)" "unprognostic (2.41e-1)" "unprognostic (4.13e-3)" "unprognostic (4.30e-2)" "unprognostic (1.18e-1)" "unprognostic (3.11e-2)" "unprognostic (6.37e-2)" "unprognostic (5.70e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.33e-1)" "unprognostic (5.22e-3)" 8.3 9.0 4.1 9.3 8.3 17.1 9.3 1.2 8.5 4.3 0.0 34.5 17.6 5.6 36.2 7.4 3.6 5.2 6.6 6.2 9.2 5.0 3.8 11.3 7.9 1.2 2.9 2.3 3.2 1.3 2.4 18.1 1.3 2.6 28.2 9.4 4.4 1.9 6.3 9.0 19.2 7.6 1.4 12.2 4.9 9.2 5.2 7.0 4.4 2.6 3.0 6.5 3.7 4.9 2.5 4.9 4.9 1.2 6.8 26.9 2.1 21.3 24.7 5.8 5.4 8.2 28.0 3.7 5.4 3.4 4.3 1.5 13.4 0.2 1.4 1.8 32.2 76.2 10.7 2.7 14.7 30.0 24.0 7.5 0.2 8.7 11.0 14.3 84.0 2.9 6.6 2.7 0.9 0.8 19.9 74.2 19.3 1.6 54.5 16.1 7.9 3.1 25.7 7.2 8.6 7.9 4.8 89.6 37.8 9.7 4.1 28.2 68.2 15.6 4.6 5.6 9.3 4.4 4.9 1.8 24.5 38.5 13.7 3.8 22.8 50.0 5.0 13.9 3.4 2.0 8.3 6.2 8.1 1.8 2.9 3.2 41.0 4.0 8.0 3.1 16.1 9.6 4.1 8.3 1.2 8.5 6.2 9.2 1.2 2.9 1.3 1.4 5.2 4.9 9.1 0.0 3.3 7.8 0.6 1.3 0.1 0.2 0.6 2.0 1.4 0.8 12.1 0.0 1.4 0.0 0.0 16.0 1.1 35.7 0.0 0.1 31.5 0.4 2.9 11.9 7.2 4.6 114.3 0.2 19.6 4.8 5.6 0.4 10.8 0.0 9.7 0.0 19.3 5.0 172.1 21.8 0.0 22.2 3.7 6.4 1.2 12.2 16.0 63.7 6.9 0.5 1.0 24.6 6.9 3.3 36.8 0.4 8.0 0.4 15.1 0.4 3.2 1.2 0.0 4.2 3.6 16.6 1.0 0.3 0.3 193.9 4.2 0.9 23.7 0.3 FARP1 "CDEP, MGC87400, PLEKHC2, PPP1R75" ENSG00000152767 "FERM, ARH/RhoGEF and pleckstrin domain protein 1" Q9Y4F1 13 98142562-98455176 "Predicted intracellular proteins" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 191.3;Early spermatids: 207.8;Inhibitory neurons: 176.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 125.3;Hep G2: 130.5;SuSa: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000760 Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "HPA000760: AB_1078816" "unprognostic (4.78e-3)" "unprognostic (1.65e-1)" "unprognostic (3.07e-1)" "unprognostic (2.01e-1)" "unprognostic (1.10e-2)" "unprognostic (2.30e-1)" "unprognostic (7.73e-2)" "unprognostic (6.91e-2)" "unprognostic (1.03e-1)" "unprognostic (6.09e-2)" "unprognostic (3.13e-1)" "unprognostic (1.08e-1)" "prognostic favorable (1.39e-5)" "unprognostic (4.89e-2)" "unprognostic (2.27e-1)" "unprognostic (2.18e-2)" "unprognostic (4.18e-2)" 17.9 35.3 40.7 10.1 43.9 1.5 24.4 24.9 40.8 26.4 18.7 41.8 8.0 19.8 23.7 8.9 18.4 18.5 13.7 42.5 37.9 68.7 67.8 32.8 6.9 35.5 35.3 16.2 45.0 14.2 23.1 28.2 30.2 41.2 12.6 8.9 37.2 25.7 19.7 14.0 13.6 23.4 35.6 13.0 32.9 14.0 38.9 3.3 43.9 15.1 3.7 27.0 16.1 28.6 0.7 10.7 47.1 66.7 13.3 26.0 22.7 72.0 46.9 39.8 34.8 83.9 31.9 0.2 27.0 125.3 9.8 1.5 20.1 19.9 66.4 1.3 20.5 0.4 38.9 130.5 35.3 0.3 0.6 30.6 8.9 11.6 2.6 23.0 26.5 1.0 0.1 0.7 27.8 18.6 2.8 0.4 22.5 40.7 12.5 25.4 18.3 1.4 88.0 46.8 20.0 43.5 8.8 18.9 51.0 110.8 26.9 0.1 25.6 42.8 16.1 29.2 37.0 0.7 0.7 0.5 19.9 1.4 30.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.7 43.9 24.9 40.8 42.5 37.9 35.5 35.3 30.2 35.6 38.9 28.6 37.3 44.8 24.8 191.3 2.6 6.9 60.2 8.8 15.4 13.9 73.3 40.8 8.4 123.0 27.5 57.0 45.9 6.7 4.0 10.9 80.3 47.5 207.8 70.3 90.5 23.9 31.1 2.7 75.3 35.1 6.4 29.9 23.4 100.7 13.3 44.5 23.2 58.4 53.5 30.3 176.4 10.1 24.4 22.7 9.3 125.9 19.0 14.0 28.4 44.0 17.5 29.6 2.1 104.5 3.7 47.0 4.4 29.3 3.1 56.8 0.3 139.6 38.6 15.7 19.7 18.7 55.4 9.2 15.9 3.2 2.8 4.5 6.4 60.4 12.6 47.2 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 372.8;breast: 271.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.0;Breast glandular cells: 442.9;Breast myoepithelial cells: 165.4;Hepatocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 1109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3400000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 372.8 30.9 25.0 14.9 44.2 18.7 271.6 67.3 49.9 31.7 0.0 25.5 11.5 18.0 6.2 63.6 15.2 6.6 21.9 39.9 15.0 11.8 191.4 54.1 7.2 84.4 75.7 16.3 18.6 8.5 72.4 12.1 101.7 69.0 3.0 4.3 38.3 14.3 27.9 89.4 28.8 5.3 12.5 8.8 63.6 11.9 33.7 9.6 21.2 2.3 3.0 27.0 31.8 60.8 179.1 182.0 81.7 56.7 130.1 87.2 176.9 34.3 43.3 35.5 64.6 190.6 116.7 58.8 29.2 26.3 99.5 144.0 79.2 157.8 6.5 30.0 358.0 123.9 140.0 257.2 36.8 67.5 19.2 84.2 40.4 90.8 21.0 12.1 40.1 54.8 193.2 50.7 12.6 304.1 78.9 105.5 161.1 28.1 107.1 64.1 47.8 116.5 40.3 220.7 205.0 117.0 50.6 1109.2 93.6 29.5 199.4 123.4 71.1 52.3 107.0 45.2 88.4 68.5 17.1 60.6 31.2 71.1 79.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 25.0 44.2 67.3 49.9 39.9 15.0 84.4 75.7 101.7 12.5 33.7 60.8 9.6 25.6 126.0 28.4 7.4 7.8 12.7 33.2 8.0 28.7 442.9 165.4 5.9 21.5 28.4 11.0 6.2 32.0 12.8 35.7 3.9 19.2 1.5 19.6 19.8 10.8 18.1 20.6 11.9 29.2 77.7 13.4 33.6 17.1 12.7 29.9 10.8 244.1 13.9 30.3 12.5 22.3 22.4 9.8 6.2 3.4 16.4 7.0 17.8 4.7 6.2 14.1 8.2 11.6 17.6 19.1 23.6 11.3 9.7 60.4 6.5 5.9 23.7 13.1 0.0 9.0 14.9 1.8 11.7 34.1 13.8 29.6 10.6 27.9 27.4 19.6 FAXC "C6orf168, dJ273F20, MGC2817" ENSG00000146267 "Failed axon connections homolog, metaxin like GST domain containing" Q5TGI0 6 99271168-99350062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Excitatory neurons: 57.1;Inhibitory neurons: 60.1;Oligodendrocyte precursor cells: 43.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 26.0;HAP1: 23.8;SCLC-21H: 34.2;SH-SY5Y: 23.7;SK-MEL-30: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039106 Uncertain Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA039106: AB_10697546" "unprognostic (8.03e-2)" "unprognostic (4.91e-2)" "unprognostic (5.04e-3)" "unprognostic (6.44e-2)" "unprognostic (3.80e-1)" "unprognostic (5.00e-3)" "unprognostic (7.56e-2)" "unprognostic (7.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.34e-2)" "unprognostic (2.79e-3)" "unprognostic (2.47e-3)" "unprognostic (6.70e-4)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.86e-2)" "unprognostic (3.49e-3)" 0.7 2.2 11.0 1.5 12.7 0.0 3.2 9.3 19.0 2.5 2.0 22.7 1.5 6.5 11.0 6.2 3.7 2.4 0.8 14.1 7.6 2.7 0.0 1.7 0.1 7.2 5.6 2.2 2.5 6.5 15.9 0.8 6.3 8.2 2.9 10.4 7.4 10.6 0.5 0.9 3.3 7.8 4.4 0.4 7.1 2.1 8.5 2.2 1.7 0.6 0.1 14.3 2.9 11.4 4.0 3.2 10.3 14.3 0.0 0.0 3.8 5.0 3.2 8.1 7.0 1.9 1.3 0.0 0.6 1.0 26.0 0.1 23.8 4.7 7.0 0.0 11.8 0.1 1.9 0.7 0.6 0.0 0.0 0.5 7.5 0.2 3.8 5.9 0.0 2.0 0.5 0.0 2.7 7.0 0.0 0.0 12.2 0.0 4.8 0.0 1.0 0.0 4.3 0.3 34.2 23.7 4.5 3.2 22.6 4.2 10.0 0.0 1.0 2.5 4.7 0.0 15.5 0.0 0.0 0.0 0.1 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 12.7 9.3 19.0 14.1 7.6 7.2 5.6 6.3 4.4 8.5 11.4 0.2 25.6 15.2 5.5 0.5 0.4 4.2 4.2 5.7 14.4 5.3 9.0 1.1 0.0 8.1 1.8 10.4 1.2 0.4 0.2 9.8 2.3 2.6 0.6 1.0 1.7 0.0 0.0 57.1 0.7 0.2 1.4 0.0 0.4 3.8 0.4 1.4 0.1 0.2 3.3 60.1 0.2 4.1 0.6 1.1 5.0 0.0 1.2 1.8 2.8 0.1 3.6 2.1 43.7 4.4 1.0 0.1 1.9 0.1 4.8 0.0 1.0 2.1 13.6 0.0 0.2 1.3 1.3 8.9 1.2 0.3 0.3 1.2 0.2 0.4 1.2 FBLIM1 "CAL, FBLP-1, migfilin" ENSG00000162458 "Filamin binding LIM protein 1" Q8WUP2 1 15756607-15786594 "Predicted intracellular proteins" "Cell adhesion, Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.3;Paneth cells: 153.6;Peritubular cells: 191.5;Proximal enterocytes: 145.9;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 255.9;TIME: 420.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025287, HPA072750" Approved Enhanced "Nucleoli fibrillar center,Cell Junctions,Focal adhesion sites" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions, Focal adhesion sites" "Nucleoli fibrillar center" "HPA025287: AB_1848443, HPA072750: AB_2686554" "unprognostic (4.10e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (2.26e-1)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.33e-2)" "unprognostic (8.77e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (2.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.33e-2)" "unprognostic (3.01e-1)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 32.4 17.9 2.7 21.5 3.3 0.8 28.1 3.2 4.8 43.2 5.2 75.6 82.2 75.7 15.6 24.1 43.5 69.8 45.6 2.5 2.4 26.7 7.1 39.3 9.6 2.6 3.2 39.1 27.5 36.2 11.0 29.4 2.9 47.0 53.2 1.8 31.7 63.1 5.4 16.8 86.1 47.1 2.5 27.6 64.0 12.8 3.8 2.8 17.6 5.6 6.8 44.6 29.3 2.6 34.2 17.2 15.9 0.6 3.7 8.1 21.6 55.2 84.3 38.4 30.4 6.0 48.8 0.3 114.5 87.8 67.3 62.5 11.3 121.0 19.2 0.3 6.6 0.2 4.7 31.7 98.5 0.2 0.6 39.7 81.7 31.9 75.1 82.7 255.9 2.0 1.2 7.6 13.2 0.8 0.6 1.1 16.5 50.9 25.0 0.1 0.4 1.0 51.4 22.1 0.2 38.9 29.0 3.4 6.0 33.9 6.8 0.6 420.4 50.7 7.1 0.8 25.7 0.4 1.0 0.5 8.0 0.2 0.5 1.7 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.5 0.3 0.3 0.8 0.4 0.2 0.4 0.1 0.1 2.7 3.3 3.2 4.8 2.5 2.4 2.6 3.2 2.9 2.5 3.8 2.6 10.8 12.8 18.1 0.0 3.1 86.3 82.7 41.4 20.5 3.7 28.6 23.9 37.1 47.1 30.6 16.5 6.2 8.9 4.8 207.3 0.0 99.1 3.4 13.6 75.9 19.2 46.0 0.0 0.7 53.5 114.2 29.3 133.5 20.5 18.9 9.4 55.0 2.5 5.6 1.7 5.5 54.8 26.4 1.9 23.5 4.0 80.2 5.8 14.2 2.8 2.7 9.1 1.0 1.0 1.2 113.0 153.6 191.5 1.2 29.8 145.9 2.5 11.6 6.4 144.7 11.9 64.8 2.8 1.9 17.4 62.8 19.4 6.0 6.6 53.8 62.6 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.9;placenta: 76.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 132.4;Fibroblasts: 388.5;Leydig cells: 236.1;Oligodendrocytes: 218.7;Peritubular cells: 227.2;Skeletal myocytes: 139.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 215.1;ASC TERT1: 460.7;fHDF/TERT166: 420.8;HSkMC: 251.3;hTERT-RPE1: 211.1;U-138 MG: 206.9;U-2197: 305.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188" Enhanced Approved Cytosol "Secreted to blood" NA NA 520000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" 60.9 4.4 1.4 14.5 5.4 3.4 13.7 2.8 2.8 36.0 9.5 8.3 3.8 15.2 6.3 12.6 12.2 27.3 23.5 0.8 2.0 2.7 2.9 10.0 3.7 5.2 6.0 28.4 3.3 3.0 2.5 76.7 3.7 8.0 11.7 1.3 4.6 13.2 4.5 5.7 6.6 35.7 2.3 6.4 6.0 7.1 4.7 2.9 18.6 21.2 3.5 18.8 9.9 5.0 0.1 5.2 19.8 22.4 215.1 460.7 0.2 175.8 62.9 51.1 32.4 0.1 0.3 0.1 7.9 420.8 0.4 0.7 3.9 0.6 45.9 20.7 1.2 2.0 88.5 0.2 120.7 0.8 0.3 251.3 0.1 135.9 15.6 211.1 55.5 1.6 0.0 0.4 55.6 0.0 1.5 0.2 4.0 0.2 7.1 0.1 17.0 0.2 5.9 0.5 0.2 12.9 0.0 2.2 0.1 15.3 0.2 1.4 106.8 206.9 6.2 305.8 37.6 1.2 1.0 0.0 138.9 0.3 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 5.4 2.8 2.8 0.8 2.0 5.2 6.0 3.7 2.3 4.7 5.0 50.0 0.0 1.3 34.9 0.4 25.6 0.8 1.5 0.6 6.1 1.3 3.4 14.2 0.0 5.8 12.9 0.0 132.4 0.4 0.0 0.0 0.2 8.7 4.2 105.2 36.1 0.0 5.5 82.3 0.6 40.8 388.5 3.1 2.0 1.3 22.5 34.6 0.6 15.3 0.0 123.5 0.0 0.0 0.8 39.0 22.8 236.1 5.7 42.7 30.0 2.3 0.8 0.0 76.9 218.7 1.7 0.0 227.2 1.7 0.7 0.1 0.6 3.3 0.2 26.3 139.5 55.8 3.3 3.4 0.8 20.6 65.8 4.3 51.3 0.0 0.2 FBP2 ENSG00000130957 "Fructose-bisphosphatase 2" O00757 9 94558720-94593824 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 753.6;tongue: 385.3" "Group enriched" "Detected in some" 7 "Gastric mucus-secreting cells: 11.2;Skeletal myocytes: 8.7;Spermatogonia: 8.5" "Cancer enhanced" "Detected in some" "stomach cancer: 1.2" "Region enriched" "Detected in some" 4 "hippocampal formation: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.9;CACO-2: 2.1;HMC-1: 2.2;MCF7: 3.0;OE19: 2.9;PC-3: 2.0;SiHa: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012513, HPA077371" Enhanced Approved "Plasma membrane,Cytosol" NA NA 960000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA012513: AB_1848446, HPA077371: " "unprognostic (3.88e-2)" "unprognostic (3.54e-4)" "unprognostic (2.38e-1)" "unprognostic (6.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-2)" "unprognostic (9.40e-4)" "unprognostic (3.95e-3)" "unprognostic (5.11e-2)" "unprognostic (2.39e-2)" "unprognostic (4.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.48e-4)" 0.1 0.9 0.1 0.1 0.0 0.0 0.2 1.2 0.1 0.0 69.2 0.3 5.3 0.0 0.0 8.1 0.0 0.1 0.2 6.1 0.0 0.2 0.2 0.4 0.4 0.7 0.3 0.0 4.3 49.7 0.0 0.1 0.1 1.2 0.0 0.0 4.2 3.3 753.6 0.2 0.9 0.0 0.9 0.0 36.1 1.4 1.4 0.2 0.3 385.3 0.9 0.3 0.0 0.0 0.3 1.3 0.0 1.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.2 1.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 2.9 2.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 2.8 0.6 0.0 0.1 0.2 0.1 0.0 0.0 1.2 1.2 0.0 0.0 0.0 0.6 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.1 6.1 0.0 0.7 0.3 0.1 0.9 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.5 1.3 0.0 0.0 11.2 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.2 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 FBRS "FBS, FBS1, FLJ11618" ENSG00000156860 Fibrosin Q9HAH7 16 30658431-30670810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044117 Approved Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA044117: AB_10794394" "unprognostic (1.87e-1)" "unprognostic (8.48e-3)" "unprognostic (2.41e-2)" "unprognostic (9.52e-3)" "unprognostic (1.03e-1)" "unprognostic (4.80e-2)" "unprognostic (2.07e-3)" "unprognostic (7.01e-3)" "unprognostic (6.32e-2)" "unprognostic (7.65e-2)" "unprognostic (4.57e-3)" "unprognostic (1.01e-1)" "unprognostic (1.25e-2)" "unprognostic (2.13e-1)" "unprognostic (4.16e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" 25.6 34.3 23.0 24.4 22.2 55.9 25.8 21.5 24.6 34.2 14.9 39.1 21.2 35.6 5.5 57.2 36.0 9.4 28.7 22.9 19.7 33.3 29.9 29.2 21.8 24.7 20.9 33.8 29.8 16.6 57.6 12.6 19.4 37.3 6.5 6.5 30.2 15.6 38.4 53.5 40.0 9.7 16.8 53.4 33.8 117.3 22.9 21.3 36.6 11.4 15.9 34.7 33.2 23.0 28.8 30.2 15.6 12.9 15.3 15.5 39.5 20.9 16.9 17.7 13.3 17.8 25.9 26.8 34.0 17.0 16.0 23.6 16.6 19.9 8.3 72.7 41.5 36.0 29.3 33.0 37.4 26.5 52.3 23.1 26.4 34.3 16.6 19.8 22.0 24.4 32.0 50.2 13.1 59.1 33.7 51.7 4.4 12.9 19.0 48.5 11.8 29.4 18.8 21.2 21.8 24.5 16.4 31.2 22.9 6.7 70.5 34.6 34.3 40.0 24.2 25.0 27.8 58.6 30.5 25.4 38.4 25.6 24.1 0.0 1.0 0.8 0.8 0.4 0.8 0.6 0.7 0.8 0.5 0.7 0.2 0.9 2.1 0.5 0.6 1.0 0.0 0.9 23.0 22.2 21.5 24.6 22.9 19.7 24.7 20.9 19.4 16.8 22.9 23.0 21.2 16.0 21.8 9.8 30.0 18.7 15.9 13.2 38.7 22.3 26.8 19.3 9.3 11.5 11.0 7.3 33.3 10.2 38.1 36.3 5.9 11.0 82.2 33.4 25.1 18.2 16.8 4.6 9.5 14.7 9.3 15.8 29.0 32.2 19.0 21.5 19.2 9.4 14.0 43.7 8.7 21.5 10.2 15.8 22.0 109.9 17.1 25.8 10.6 7.5 20.1 14.7 15.5 7.5 14.5 21.1 26.3 16.1 13.3 22.2 33.5 8.9 24.4 25.7 0.0 19.0 17.7 69.1 23.9 37.8 24.3 33.0 28.8 22.2 19.3 27.9 FBXL22 "Fbl22, FLJ39626" ENSG00000197361 "F-box and leucine rich repeat protein 22" Q6P050 15 63597353-63602428 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 60.4;intestine: 60.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "MCF7: 4.9;SCLC-21H: 5.3;U-937: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA047624, HPA054627" Uncertain Uncertain Nucleoli,Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli, Cytosol" "HPA047624: AB_2680107, HPA054627: AB_2682548" "unprognostic (2.17e-1)" "unprognostic (3.19e-2)" "unprognostic (2.99e-3)" "unprognostic (5.28e-2)" "unprognostic (3.03e-2)" "unprognostic (1.29e-2)" "unprognostic (1.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.53e-1)" "unprognostic (1.65e-1)" "unprognostic (2.82e-2)" "unprognostic (1.34e-1)" "unprognostic (1.07e-3)" "unprognostic (1.90e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-2)" "unprognostic (1.02e-2)" 3.6 0.9 1.9 2.8 1.7 0.3 1.8 2.7 2.0 15.7 0.2 60.1 2.9 60.4 3.6 7.0 21.2 8.8 17.2 1.6 1.3 1.0 0.5 1.1 0.9 0.8 1.1 4.5 0.7 0.6 0.7 0.9 0.9 16.9 4.8 0.6 3.2 29.4 4.9 1.4 7.3 28.9 0.5 0.6 11.1 3.0 1.8 0.4 1.5 1.8 0.2 26.3 10.1 1.0 0.7 1.2 0.2 0.8 0.5 0.5 0.1 0.2 0.0 0.3 0.0 0.8 0.9 0.3 0.7 0.2 0.4 0.8 0.6 0.4 0.0 0.8 0.6 0.3 1.1 2.2 0.1 0.4 0.1 0.2 0.2 0.1 0.5 0.1 0.2 2.2 0.0 1.1 0.0 4.9 0.7 0.7 1.7 0.8 0.4 0.7 0.0 2.4 0.3 0.3 5.3 0.2 0.6 1.0 0.3 0.0 1.9 0.6 0.8 0.3 1.0 0.5 0.2 0.7 1.5 0.8 0.5 3.7 0.8 0.2 0.0 0.0 0.5 0.0 0.5 0.6 0.6 0.6 0.0 0.4 1.0 0.4 0.1 0.7 0.0 1.6 0.0 0.2 1.9 1.7 2.7 2.0 1.6 1.3 0.8 1.1 0.9 0.5 1.8 1.0 1.4 0.0 0.0 1.0 3.4 0.1 1.8 0.4 0.6 10.1 4.7 8.6 7.7 2.8 0.7 7.3 4.2 0.7 2.7 2.3 9.8 1.2 0.9 3.2 5.8 1.3 4.9 2.5 1.5 1.1 1.2 3.4 7.7 5.8 0.0 0.9 3.9 4.0 0.7 0.0 1.8 6.1 0.0 1.6 0.4 0.5 0.3 1.7 0.0 0.0 0.7 10.6 2.1 1.5 0.5 0.8 3.0 11.3 9.1 1.7 1.9 4.0 0.1 3.8 0.0 6.2 8.1 3.8 3.2 4.4 0.9 0.5 4.4 2.7 4.0 0.8 FBXO16 FBX16 ENSG00000214050 "F-box protein 16" Q8IX29 8 28348287-28490278 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 18.4;pituitary gland: 17.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Excitatory neurons: 44.4;Inhibitory neurons: 43.6;Rod photoreceptor cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 9.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 9.6" "Cell line enhanced" "Detected in many" "AF22: 20.3;Karpas-707: 22.4" "Low region specificity" "Detected in all" "HPA058676, HPA076472" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Plasma membrane, Cytosol" "HPA058676: AB_2683795, HPA076472: " "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (3.37e-3)" "unprognostic (5.56e-3)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (4.95e-3)" "unprognostic (6.49e-2)" "prognostic favorable (6.70e-5)" "unprognostic (3.41e-3)" "unprognostic (4.90e-2)" "unprognostic (7.15e-2)" "unprognostic (1.71e-2)" "unprognostic (4.85e-2)" "unprognostic (2.72e-2)" "unprognostic (2.07e-1)" 0.5 1.8 3.9 0.9 5.0 2.2 2.6 6.8 7.0 4.1 2.9 1.6 2.0 1.1 18.4 0.7 4.4 1.4 1.4 4.6 3.9 3.2 6.0 1.5 1.4 1.1 1.7 0.7 4.7 7.1 17.3 0.6 2.0 3.5 2.0 14.3 3.4 5.1 1.1 0.4 2.9 0.7 0.3 1.2 2.2 4.2 3.5 0.6 7.0 0.9 2.8 1.2 0.7 4.3 16.5 2.9 20.3 7.5 0.5 0.0 0.3 0.2 0.5 3.0 5.5 3.1 4.6 5.8 7.2 0.1 8.1 5.1 2.3 3.5 3.0 2.6 3.6 2.7 0.3 1.7 0.0 3.5 1.9 0.2 10.8 0.7 3.2 1.5 0.0 5.6 1.1 22.4 1.0 5.7 0.5 5.0 3.9 2.2 4.5 0.2 4.5 8.2 3.9 2.4 13.1 5.4 0.4 3.3 9.5 3.5 13.8 5.9 0.6 1.6 5.8 3.2 3.0 5.2 5.0 5.2 6.8 0.7 3.5 0.3 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.2 0.1 0.2 0.9 0.0 0.1 9.6 0.2 0.1 3.9 5.0 6.8 7.0 4.6 3.9 1.1 1.7 2.0 0.3 3.5 4.3 0.0 3.2 4.1 7.5 1.7 0.1 3.0 10.9 5.2 8.2 3.9 3.4 2.1 8.6 7.9 3.7 35.5 0.6 0.0 0.5 7.9 5.3 12.1 13.5 1.3 0.2 10.2 0.0 44.4 4.6 0.4 0.9 1.5 6.4 0.0 1.9 0.4 1.9 2.7 5.0 43.6 3.9 4.1 0.8 2.3 12.4 1.2 0.4 0.0 2.8 0.0 9.3 0.0 23.6 3.2 3.1 0.4 0.7 11.1 1.7 0.2 4.7 23.4 48.6 0.0 0.5 1.8 10.5 5.6 1.2 0.0 0.0 0.5 4.2 1.0 1.7 FBXO27 "Fbg5, Fbx27" ENSG00000161243 "F-box protein 27" Q8NI29 19 38990714-39032785 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 37.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.1;Suprabasal keratinocytes: 17.8;Syncytiotrophoblasts: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 35.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA046800, HPA062242" Approved Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA046800: AB_2679813, HPA062242: AB_2684723" "prognostic favorable (2.15e-4)" "unprognostic (7.32e-2)" "unprognostic (2.03e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (1.48e-3)" "unprognostic (4.38e-3)" "unprognostic (1.02e-1)" "unprognostic (8.95e-2)" "unprognostic (1.67e-1)" "unprognostic (7.31e-3)" "unprognostic (6.80e-2)" "unprognostic (9.31e-2)" "unprognostic (2.25e-2)" "unprognostic (8.72e-3)" "unprognostic (6.04e-2)" "unprognostic (7.51e-2)" "unprognostic (3.21e-2)" 13.3 3.7 17.5 2.1 15.9 2.7 6.2 23.8 18.7 6.3 6.4 6.8 2.2 4.7 2.4 15.4 5.3 5.5 19.6 15.4 8.9 6.4 7.5 3.2 3.7 10.7 6.7 10.2 4.8 2.5 4.1 3.8 9.1 8.9 8.7 4.9 7.4 7.8 1.6 37.5 4.9 7.4 4.9 3.1 3.8 4.7 11.1 4.0 4.6 2.4 4.0 7.7 9.7 13.1 9.1 11.4 0.3 7.2 15.3 0.8 3.3 1.2 6.7 5.2 4.9 3.8 3.4 0.9 17.5 10.3 9.0 15.5 0.6 6.6 3.4 0.8 0.4 0.3 3.0 0.6 2.7 0.9 2.5 5.5 10.2 5.4 0.4 8.2 3.3 0.4 5.4 1.2 7.2 8.1 0.6 1.4 8.1 3.0 20.4 0.2 0.1 1.1 3.4 35.3 0.4 10.8 17.7 2.2 0.1 4.8 9.2 1.7 4.0 0.5 0.4 0.3 0.9 3.5 8.9 1.9 9.0 0.2 0.3 1.1 0.3 0.2 0.3 0.3 0.2 0.4 0.2 0.2 0.2 0.6 0.4 0.3 1.7 1.7 0.2 0.5 0.3 0.2 17.5 15.9 23.8 18.7 15.4 8.9 10.7 6.7 9.1 4.9 11.1 13.1 0.2 3.2 15.0 2.3 0.1 5.9 4.1 1.4 9.1 7.5 3.8 4.2 9.5 7.2 6.4 1.8 0.0 36.1 0.5 0.2 1.9 1.5 3.7 1.9 3.6 3.2 0.0 0.0 4.8 0.8 4.8 2.7 6.1 1.6 7.6 2.3 1.4 3.2 4.9 8.4 4.6 0.2 8.2 0.3 4.9 2.5 2.8 2.1 0.0 1.0 1.1 5.6 0.0 3.0 4.1 0.3 0.0 4.1 1.9 2.3 6.9 7.3 4.7 3.0 0.0 1.8 1.5 6.4 2.0 13.5 17.8 27.0 1.3 0.4 0.2 5.3 FBXO28 "CENP-30, Fbx28, FLJ10766, KIAA0483" ENSG00000143756 "F-box protein 28" Q9NVF7 1 224114111-224162047 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003289 Approved Supported "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Focal adhesion sites" "HPA003289: AB_2666879" "unprognostic (4.91e-2)" "unprognostic (5.57e-2)" "unprognostic (1.78e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.12e-1)" "unprognostic (8.25e-2)" "unprognostic (2.03e-1)" "unprognostic (7.09e-2)" "unprognostic (5.09e-3)" "unprognostic (2.60e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-2)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (2.61e-1)" 10.9 7.5 6.5 8.3 7.3 8.9 12.3 8.8 10.5 10.9 7.4 10.3 8.5 10.0 7.9 12.4 8.2 9.5 8.1 7.6 9.1 13.6 17.4 8.9 10.5 8.5 7.4 11.3 7.6 13.7 4.4 9.0 8.8 10.0 10.6 8.3 7.9 8.5 12.5 21.1 7.7 9.8 8.0 8.9 8.5 7.8 7.8 10.9 9.8 14.2 10.6 11.5 9.0 8.9 24.6 10.6 16.2 17.4 16.6 19.0 26.7 24.3 19.7 16.0 15.2 14.9 18.7 11.8 24.4 22.3 10.3 20.9 24.2 23.4 27.4 17.0 27.0 15.0 12.8 10.7 20.7 28.3 18.8 18.6 27.7 23.2 41.9 18.8 27.1 15.0 24.8 16.4 29.1 8.1 14.9 14.4 38.6 32.3 22.8 15.7 23.1 22.3 30.2 16.1 26.2 28.1 25.1 38.0 27.4 16.9 20.2 28.2 31.2 19.8 15.0 25.0 46.1 17.8 22.3 18.0 24.5 13.7 39.3 7.4 6.5 11.8 5.8 6.0 7.2 8.9 5.9 6.8 7.8 9.0 5.9 6.6 4.2 8.6 6.9 3.5 8.8 4.6 6.5 7.3 8.8 10.5 7.6 9.1 8.5 7.4 8.8 8.0 7.8 8.9 15.0 6.4 10.6 22.5 16.8 34.3 25.5 11.3 9.6 20.5 14.7 11.7 11.4 7.2 13.5 11.0 22.9 14.2 12.3 17.2 9.8 13.2 30.3 15.9 13.0 16.4 18.5 17.4 48.8 11.5 13.1 12.7 7.1 22.9 14.0 12.6 14.3 23.4 13.9 18.5 43.8 12.7 14.2 17.7 16.3 14.8 13.1 16.8 28.4 34.7 16.4 12.6 7.2 45.8 43.7 17.7 12.2 13.2 15.4 21.5 12.0 22.8 11.5 18.6 13.1 14.9 12.7 24.7 26.8 17.2 39.1 23.0 18.9 10.9 14.6 30.7 FBXO30 "Fbx30, MGC21674" ENSG00000118496 "F-box protein 30" Q8TB52 6 145793502-145814795 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 9.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012583 Approved Approved Microtubules NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 40: Granulosa cells - Unknown function" Microtubules "HPA012583: AB_2668686" "unprognostic (8.69e-2)" "unprognostic (3.35e-3)" "unprognostic (2.92e-2)" "unprognostic (4.29e-2)" "unprognostic (5.47e-3)" "unprognostic (8.36e-2)" "unprognostic (7.61e-7)" "unprognostic (5.79e-2)" "unprognostic (1.63e-1)" "unprognostic (6.32e-2)" "unprognostic (1.18e-2)" "unprognostic (9.25e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (5.72e-2)" "unprognostic (1.68e-1)" "unprognostic (1.78e-1)" 4.5 4.0 3.8 4.2 5.0 7.2 4.0 4.6 3.9 4.1 2.7 9.7 4.1 6.7 3.1 9.6 3.2 5.6 7.2 3.1 6.0 4.1 3.4 3.2 4.3 4.5 5.5 5.9 3.8 4.0 1.6 4.8 4.7 6.0 4.7 5.3 4.4 6.8 11.5 2.6 3.5 8.0 4.2 3.7 3.7 6.5 5.1 2.9 8.0 9.1 4.1 5.7 2.9 5.3 3.7 6.9 9.7 13.2 9.9 8.8 9.9 10.3 9.6 6.9 6.8 8.7 3.3 17.0 7.8 11.8 12.6 5.7 8.4 7.5 10.4 10.0 5.8 10.8 9.1 8.8 17.8 14.1 10.8 14.6 8.3 8.6 11.4 9.0 10.1 4.1 12.6 11.9 13.6 2.9 6.4 7.5 11.2 2.4 5.1 8.2 21.7 5.9 7.2 3.8 4.3 6.9 12.6 6.5 6.1 9.6 3.0 13.8 13.4 7.1 6.0 9.1 10.4 8.8 7.2 6.8 11.4 6.0 7.7 9.3 1.3 1.6 0.4 1.1 0.3 0.6 0.4 0.8 1.6 1.3 0.6 0.6 1.2 0.5 0.9 0.5 0.3 0.6 3.8 5.0 4.6 3.9 3.1 6.0 4.5 5.5 4.7 4.2 5.1 5.3 11.1 3.2 5.9 7.2 5.4 14.3 5.3 4.2 12.5 8.8 10.5 8.3 22.9 10.0 4.7 3.7 4.2 5.8 5.7 4.9 11.7 4.7 10.9 4.1 13.7 13.8 6.0 36.7 5.3 3.2 3.4 15.4 7.1 6.2 12.0 37.1 11.4 9.7 7.5 26.9 6.4 5.0 2.0 11.9 20.8 4.4 11.1 10.2 7.2 7.5 7.5 12.0 0.0 5.0 7.6 5.1 3.2 10.1 11.1 7.1 4.3 8.2 2.8 8.7 0.0 26.5 18.4 19.7 10.5 12.4 17.3 5.6 6.2 7.2 5.0 5.0 FBXO42 "Fbx42, KIAA1332" ENSG00000037637 "F-box protein 42" Q6P3S6 1 16246840-16352480 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025071 Approved Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA025071: AB_1848461" "unprognostic (1.08e-1)" "unprognostic (2.38e-1)" "unprognostic (1.25e-1)" "unprognostic (3.09e-2)" "unprognostic (1.40e-1)" "unprognostic (1.11e-2)" "prognostic unfavorable (3.72e-4)" "unprognostic (3.22e-2)" "unprognostic (4.00e-2)" "unprognostic (4.22e-2)" "unprognostic (3.96e-2)" "unprognostic (4.61e-2)" "unprognostic (1.22e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-1)" "unprognostic (5.78e-3)" "unprognostic (3.91e-2)" 14.1 12.6 17.4 8.8 16.4 9.3 12.9 20.0 18.0 21.7 14.7 15.1 7.6 19.8 12.9 18.2 18.6 11.8 16.9 16.5 17.6 11.8 14.2 13.6 12.5 16.9 16.3 18.2 15.3 14.0 16.2 12.1 17.8 19.3 10.6 16.7 13.5 15.0 22.6 28.1 11.1 17.9 14.9 13.7 12.1 11.6 16.8 18.1 14.6 22.3 14.3 18.9 17.9 16.4 15.4 8.2 19.4 19.8 23.1 15.0 8.5 15.6 23.5 22.0 21.4 7.7 13.9 16.2 13.6 21.7 15.1 13.6 19.8 14.8 17.9 18.7 9.3 15.2 12.5 8.8 27.5 18.1 19.0 16.1 33.5 19.4 27.8 20.0 22.3 20.0 16.5 22.1 15.8 10.5 17.5 15.8 8.5 20.3 9.2 19.6 11.9 14.5 14.8 4.3 18.3 12.0 17.6 14.6 18.8 17.7 11.9 14.0 14.0 11.1 9.8 18.4 12.3 10.9 11.9 16.3 14.7 23.5 15.6 9.0 11.8 18.5 11.7 16.3 8.7 8.5 8.7 7.5 14.0 14.1 9.8 8.7 10.5 12.4 12.7 6.1 12.4 7.9 17.4 16.4 20.0 18.0 16.5 17.6 16.9 16.3 17.8 14.9 16.8 16.4 9.2 12.8 11.8 47.0 16.0 25.9 6.1 13.5 22.2 21.7 7.1 7.1 20.6 15.7 9.4 12.9 45.9 11.0 16.6 6.7 0.0 8.5 9.4 21.7 15.5 9.9 10.7 10.8 63.9 7.6 15.6 14.7 11.7 33.1 2.5 12.8 9.7 9.6 13.8 28.6 65.9 5.6 10.2 15.1 28.1 10.2 14.9 13.4 1.8 35.6 19.2 11.0 15.5 60.8 53.0 8.4 7.6 11.3 17.7 10.4 8.8 3.8 6.4 20.4 13.1 23.1 13.4 13.5 9.7 18.9 34.7 26.3 16.0 9.8 8.3 5.5 FBXO45 Fbx45 ENSG00000174013 "F-box protein 45" P0C2W1 3 196568611-196589059 "Predicted intracellular proteins" "Neurogenesis, Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040730 Uncertain Approved Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA040730: AB_10959311" "unprognostic (7.17e-3)" "unprognostic (1.14e-1)" "unprognostic (8.37e-2)" "unprognostic (1.01e-2)" "unprognostic (8.14e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.61e-5)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.13e-2)" "unprognostic (9.48e-3)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.16e-5)" "prognostic unfavorable (4.93e-5)" "unprognostic (5.18e-2)" "unprognostic (1.66e-1)" "unprognostic (6.93e-2)" "unprognostic (1.65e-1)" 5.1 4.2 10.7 6.1 11.5 13.9 7.3 11.8 14.8 4.5 6.8 6.9 5.3 4.7 3.0 8.9 3.6 4.4 3.6 11.0 10.9 3.7 6.9 4.5 6.7 10.7 10.9 5.0 4.6 7.2 3.1 5.4 10.4 5.1 7.0 8.2 4.0 4.3 13.8 12.7 5.1 5.0 11.6 5.1 5.5 12.2 11.5 8.8 3.7 11.5 10.0 6.8 5.0 11.7 45.5 8.5 17.6 22.4 11.6 11.4 20.9 19.7 9.0 15.3 15.6 23.9 15.1 19.1 33.1 12.8 22.8 19.0 33.9 22.5 28.1 27.7 15.3 34.8 15.5 15.1 11.1 46.9 17.1 5.8 24.9 17.3 31.8 8.0 16.9 30.5 42.4 39.2 17.2 45.3 27.5 21.9 27.4 40.3 32.5 23.1 23.0 46.2 12.9 18.3 35.6 24.4 21.4 36.8 23.5 15.4 63.3 31.1 16.8 17.7 19.1 25.7 53.8 38.3 68.5 52.6 15.4 59.6 17.3 1.3 0.9 1.1 0.8 0.9 1.4 0.5 0.8 0.5 1.2 0.8 0.8 0.9 0.4 0.6 1.1 1.4 1.6 0.4 10.7 11.5 11.8 14.8 11.0 10.9 10.7 10.9 10.4 11.6 11.5 11.7 10.2 12.8 4.1 6.5 6.6 9.8 10.2 5.6 4.6 20.1 10.5 7.7 10.8 4.3 4.2 3.7 14.6 2.6 11.5 7.9 0.0 4.4 15.5 8.0 12.9 8.0 17.4 6.1 13.8 7.7 4.6 7.8 10.7 8.8 1.3 6.9 7.9 9.9 5.8 13.5 15.0 8.2 4.1 9.1 11.0 18.9 5.6 7.6 5.4 8.4 8.3 9.3 4.1 6.6 12.4 8.3 4.8 6.4 8.0 14.8 4.0 3.4 6.8 10.7 0.0 10.5 7.5 32.4 24.4 9.4 13.5 1.9 8.2 7.1 9.8 14.5 FBXO48 ENSG00000204923 "F-box protein 48" Q5FWF7 2 68459422-68467294 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Alveolar cells type 2: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA049775, HPA054782" Uncertain Approved "Nuclear bodies" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 54: Non-specific - Microtubule organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear bodies" "HPA049775: AB_2680874, HPA054782: AB_2682599" "unprognostic (2.90e-1)" "unprognostic (2.62e-2)" "unprognostic (2.25e-1)" "unprognostic (2.75e-3)" "unprognostic (6.56e-3)" "unprognostic (2.90e-3)" "unprognostic (2.30e-1)" "unprognostic (4.74e-2)" "unprognostic (6.01e-3)" "unprognostic (3.92e-2)" "unprognostic (3.81e-2)" "unprognostic (2.33e-1)" "unprognostic (2.09e-2)" "unprognostic (6.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.39e-3)" "unprognostic (1.89e-2)" 1.1 1.2 1.3 1.4 1.8 0.7 1.3 1.5 1.5 1.1 1.2 1.1 1.8 0.8 1.1 1.1 0.7 0.8 0.7 1.3 1.2 1.4 2.0 1.0 1.7 1.5 1.4 1.7 0.8 1.3 0.5 1.2 1.7 0.8 1.2 3.0 1.3 0.7 3.1 2.5 1.5 0.6 1.2 1.8 1.3 1.0 1.7 1.2 1.1 1.8 1.8 0.7 0.9 2.7 2.1 0.7 1.3 0.9 1.6 1.8 0.9 1.5 1.8 1.4 1.6 1.0 0.9 2.6 1.0 0.7 1.9 1.1 1.2 1.2 2.7 3.5 1.3 1.3 0.7 0.5 0.7 0.6 1.5 0.8 2.1 2.0 1.7 0.7 0.6 4.3 0.6 4.9 1.1 0.4 1.5 1.9 0.7 1.4 1.0 1.3 2.3 1.7 1.1 0.6 1.3 0.9 0.7 0.3 1.7 1.1 0.4 0.6 0.6 1.6 1.5 2.0 1.6 3.9 2.5 1.1 1.0 1.1 1.2 2.6 0.7 0.9 1.0 0.7 1.0 0.9 1.7 1.0 0.4 1.0 1.2 1.2 1.4 1.0 1.3 0.9 2.1 0.6 1.3 1.8 1.5 1.5 1.3 1.2 1.5 1.4 1.7 1.2 1.7 2.7 9.1 32.1 52.0 1.3 6.4 7.1 5.0 3.1 9.1 3.9 7.7 10.4 11.7 7.2 16.3 5.5 2.1 4.2 4.5 7.1 11.7 3.2 1.7 4.0 3.1 8.2 3.0 4.0 0.8 3.3 3.5 6.8 3.1 4.1 12.6 2.1 5.3 7.1 4.1 3.3 0.8 6.2 0.0 5.1 6.6 1.0 4.1 8.7 1.8 0.0 2.5 2.2 2.1 1.5 1.7 3.1 2.7 1.5 5.8 3.4 7.4 9.2 12.9 5.7 0.0 5.5 3.9 18.0 11.1 6.7 8.0 1.6 8.1 2.8 3.5 3.9 FBXO5 "EMI1, FBX5, Fbxo31" ENSG00000112029 "F-box protein 5" Q9UKT4 6 152970519-152983579 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.1;lymphoid tissue: 27.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 36.0;Extravillous trophoblasts: 30.5;Spermatocytes: 32.3;Spermatogonia: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008106, HPA029048" Approved Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB008106: AB_828450, HPA029048: AB_10602132" "unprognostic (1.22e-2)" "unprognostic (7.21e-2)" "unprognostic (4.61e-3)" "unprognostic (1.24e-2)" "unprognostic (5.92e-2)" "unprognostic (2.94e-2)" "unprognostic (2.43e-8)" "unprognostic (2.46e-2)" "unprognostic (1.55e-2)" "unprognostic (7.32e-2)" "unprognostic (2.89e-1)" "unprognostic (5.86e-2)" "unprognostic (1.25e-9)" "prognostic favorable (8.65e-4)" "unprognostic (1.20e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-1)" 3.1 3.1 1.5 7.3 1.6 44.1 4.5 2.6 2.1 4.0 1.9 5.0 4.6 5.3 4.5 3.7 3.0 2.6 1.8 1.4 1.7 3.1 4.4 3.4 14.9 1.6 1.6 4.1 3.0 2.3 2.1 6.3 1.7 3.0 5.1 3.3 2.7 2.9 0.9 4.3 4.3 5.0 1.6 5.5 4.6 3.9 1.8 27.3 4.4 2.6 14.6 4.0 3.0 2.0 33.7 17.2 70.8 48.1 5.3 10.8 22.6 79.9 35.5 58.7 65.6 35.6 19.8 81.6 23.9 21.3 39.7 31.4 56.4 26.7 70.0 44.2 50.6 82.3 24.1 38.7 10.2 74.4 48.6 7.7 4.9 39.8 30.9 14.3 27.3 42.3 88.2 74.5 53.9 25.7 85.2 47.6 41.5 25.8 25.0 71.0 56.8 52.8 20.8 18.0 46.1 47.9 56.6 30.2 15.6 24.7 21.8 68.7 20.6 43.9 57.4 51.1 94.8 24.9 29.5 120.4 31.9 54.3 54.2 0.0 1.9 0.0 2.8 2.5 4.0 5.1 4.7 5.2 3.7 5.0 4.6 4.8 0.0 7.1 3.2 4.3 6.6 2.5 1.5 1.6 2.6 2.1 1.4 1.7 1.6 1.6 1.7 1.6 1.8 2.0 6.0 0.0 1.1 1.3 9.8 9.9 3.7 4.0 7.4 3.2 5.7 5.2 1.8 2.8 3.9 1.8 6.2 15.2 13.5 2.6 3.9 3.0 0.4 2.3 10.5 5.7 4.8 36.0 1.0 1.6 30.5 9.1 7.7 4.0 2.5 16.6 5.0 1.9 7.9 1.7 0.9 6.1 2.0 3.2 6.1 0.1 4.4 5.3 1.8 1.9 4.2 4.1 9.2 1.5 2.1 1.5 0.5 6.0 24.7 3.6 1.5 3.6 1.9 3.6 13.1 8.6 8.9 32.3 26.1 10.2 5.3 5.9 7.9 8.0 6.3 2.0 FBXO6 "FBG2, FBS2, FBX6, Fbx6b" ENSG00000116663 "F-box protein 6" Q9NRD1 1 11664200-11674354 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.6;Late spermatids: 117.8;NK-cells: 60.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051175 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA051175: AB_2681372" "unprognostic (3.23e-3)" "unprognostic (2.58e-2)" "unprognostic (8.27e-2)" "unprognostic (2.69e-3)" "unprognostic (1.11e-1)" "unprognostic (6.64e-2)" "unprognostic (9.46e-3)" "unprognostic (1.22e-1)" "unprognostic (1.18e-1)" "prognostic favorable (7.12e-4)" "unprognostic (1.47e-2)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.83e-6)" "unprognostic (2.65e-2)" "unprognostic (2.11e-1)" "unprognostic (5.23e-2)" "prognostic favorable (5.90e-4)" 6.5 10.7 9.9 11.8 10.1 20.3 6.7 10.3 12.4 7.6 8.2 7.6 13.5 5.0 6.0 10.3 14.1 8.7 10.0 9.8 11.5 7.8 18.5 11.4 18.3 9.9 10.5 5.9 13.8 13.5 6.1 2.6 9.7 8.7 6.8 3.6 13.0 8.4 18.7 9.5 8.2 7.4 10.0 13.0 9.8 10.8 12.6 7.1 6.7 14.5 11.1 9.5 7.0 9.8 10.0 7.3 0.8 0.4 2.1 6.8 4.5 4.2 6.6 20.1 9.2 7.6 8.3 0.3 18.7 7.0 5.5 0.2 6.8 7.5 1.5 26.3 1.0 0.2 1.0 7.7 15.4 9.4 0.1 7.9 15.8 2.5 6.3 4.3 2.6 10.3 22.7 18.7 1.8 19.1 3.4 7.8 0.8 10.2 9.7 2.3 0.1 0.7 6.9 1.4 1.6 2.0 9.3 10.9 14.3 1.8 10.5 10.2 2.0 1.0 0.8 2.7 0.3 10.0 7.5 3.9 1.2 21.6 1.8 17.1 49.5 65.0 47.0 75.0 25.4 15.3 12.0 31.3 66.5 15.0 7.1 23.7 41.4 41.4 91.0 27.3 13.1 36.6 9.9 10.1 10.3 12.4 9.8 11.5 9.9 10.5 9.7 10.0 12.6 9.8 6.0 6.4 6.9 3.3 8.4 7.0 6.6 14.6 4.0 4.3 8.3 7.4 6.8 2.8 15.0 9.2 2.1 1.1 19.5 10.7 0.0 14.5 60.6 15.7 4.5 4.0 4.9 1.7 1.8 38.5 9.2 7.8 8.6 5.3 3.8 2.2 8.2 19.9 26.2 5.0 2.6 8.3 8.2 15.4 34.7 117.8 8.1 18.3 7.2 1.0 37.8 9.0 60.8 0.0 1.3 13.0 10.8 11.3 12.2 11.3 14.3 15.6 36.5 7.8 0.0 3.3 4.0 4.0 11.9 7.3 9.8 1.8 16.0 1.8 9.2 11.2 FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536092 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 201.8;Excitatory neurons: 529.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB013793: AB_2533451, CAB029987: AB_2246842" "unprognostic (3.32e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (3.08e-2)" "unprognostic (3.87e-1)" "unprognostic (1.36e-3)" "unprognostic (4.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (3.29e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (3.38e-2)" "unprognostic (1.41e-1)" "unprognostic (5.49e-3)" "unprognostic (2.17e-3)" 14.2 9.5 37.9 15.0 43.1 19.8 14.2 54.3 66.9 8.7 6.7 9.5 7.8 8.6 24.3 14.3 15.6 9.2 24.7 48.2 23.0 6.7 11.2 11.4 16.1 17.1 20.9 9.1 12.8 7.8 9.2 9.4 18.1 7.8 10.3 18.0 11.8 7.5 26.0 63.1 10.4 9.1 11.8 16.2 13.0 22.8 29.4 14.7 10.3 19.7 20.3 11.9 10.7 47.4 9.8 8.0 19.1 14.2 12.2 9.4 16.2 13.4 12.9 8.5 8.1 15.7 12.0 24.7 3.9 13.7 6.5 5.2 16.9 30.9 12.1 16.2 8.0 11.9 10.7 10.9 12.7 29.2 10.6 14.8 45.7 15.2 24.4 8.4 15.2 20.5 19.2 25.7 10.8 13.7 34.9 10.6 9.7 8.0 6.1 32.2 8.0 5.3 9.8 17.0 12.7 10.2 8.5 11.3 7.5 21.6 6.4 12.6 15.6 11.3 12.6 5.4 8.2 79.0 47.5 24.4 9.4 9.2 8.3 23.5 2.7 1.6 4.0 3.0 2.7 2.8 3.1 2.7 1.6 1.8 3.4 2.5 4.8 7.1 2.2 2.1 2.9 1.3 37.9 43.1 54.3 66.9 48.2 23.0 17.1 20.9 18.1 11.8 29.4 47.4 29.5 9.6 22.9 80.0 48.1 201.8 36.5 29.9 120.1 74.9 32.1 30.9 61.8 12.8 15.1 9.2 31.3 10.9 54.7 22.2 3.9 14.3 17.4 37.7 37.3 36.1 14.5 30.1 529.6 13.5 39.9 27.2 21.4 61.6 15.8 19.1 17.9 18.3 10.5 11.8 186.5 16.4 32.6 18.8 47.0 10.2 15.2 33.7 28.4 172.4 28.0 37.0 35.0 102.5 99.8 18.7 18.2 11.3 174.5 36.3 8.9 7.5 11.9 41.4 13.1 33.2 25.5 74.1 87.2 57.0 174.9 31.2 46.2 18.7 14.9 70.5 FCER1A FCE1A ENSG00000179639 "Fc fragment of IgE receptor Ia" P12319 1 159289714-159308224 "FDA approved drug targets, Predicted membrane proteins" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 33.6" "Cell type enriched" "Detected in many" 7 "Langerhans cells: 1962.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 21557.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 21557.7" "Cell line enriched" "Detected in some" 99 "HEL: 447.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB022102, HPA036051, CAB055526" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "CAB022102: , CAB055526: , HPA036051: AB_2674919" "unprognostic (1.78e-2)" "unprognostic (2.26e-2)" "unprognostic (7.32e-2)" "unprognostic (7.51e-2)" "unprognostic (1.32e-2)" "unprognostic (1.44e-3)" "unprognostic (7.19e-2)" "unprognostic (1.97e-3)" "unprognostic (2.44e-1)" "unprognostic (7.20e-2)" "unprognostic (8.54e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.20e-4)" "unprognostic (1.68e-2)" "unprognostic (1.18e-1)" "unprognostic (2.70e-1)" "unprognostic (3.39e-2)" 3.9 1.7 0.4 5.7 0.4 14.2 17.3 0.5 0.8 10.6 0.5 7.0 7.1 7.1 5.4 23.0 2.9 14.9 3.2 0.4 0.6 4.7 4.4 14.5 2.5 0.6 0.5 0.7 1.2 2.6 0.8 0.2 0.7 5.9 10.7 0.1 4.0 9.1 2.8 33.6 8.8 7.4 0.4 8.0 3.5 2.3 0.6 4.8 1.2 3.9 10.9 11.9 2.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 447.9 0.0 0.0 0.0 0.5 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21557.7 14.4 36.4 0.4 4.1 4.4 2.8 4.4 1.5 2645.6 3.1 2.3 3.4 17.2 14.6 11.0 361.0 2.8 132.1 0.4 0.4 0.5 0.8 0.4 0.6 0.6 0.5 0.7 0.4 0.6 0.5 1.6 6.4 33.1 0.3 5.5 37.7 0.1 0.0 0.6 0.0 0.6 1.8 0.6 0.0 1.8 0.0 0.0 0.0 76.8 0.0 0.0 0.0 0.3 0.1 0.0 3.4 0.0 37.8 0.0 0.0 0.1 4.2 0.0 0.1 270.7 0.0 0.0 0.0 6.4 0.0 0.1 0.0 0.0 4.0 1962.9 1.1 0.0 169.1 46.2 0.0 46.8 0.0 3.1 0.0 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.0 1.5 0.0 13.1 0.1 2.6 0.1 0.3 0.2 34.1 0.0 6.8 0.0 0.0 0.0 FCGBP FC(GAMMA)BP ENSG00000275395 "Fc fragment of IgG binding protein" 19 39863323-39934626 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.9;salivary gland: 85.4;stomach 1: 85.5;thyroid gland: 99.9" "Cell type enriched" "Detected in many" 9 "Intestinal goblet cells: 6081.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;Daudi: 1.8;JURKAT: 1.7;MOLT-4: 1.8;RH-30: 7.1" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" 5.9 10.0 5.1 14.0 7.2 0.4 3.2 4.0 8.4 56.4 15.0 206.9 68.7 1.2 0.6 4.6 9.8 49.2 2.9 5.6 6.8 11.3 1.0 1.9 0.9 20.1 10.6 3.7 4.9 0.5 3.4 2.9 11.1 3.8 67.7 0.6 85.4 1.4 0.4 14.8 148.7 2.6 5.9 1.5 85.5 2.9 14.0 1.5 99.9 0.0 0.7 3.4 1.6 12.0 0.0 4.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.1 1.8 0.6 0.1 1.5 0.3 0.1 7.1 1.6 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.0 0.1 5.1 7.2 4.0 8.4 5.6 6.8 20.1 10.6 11.1 5.9 14.0 12.0 0.6 3.2 5.1 2.6 4.6 3.7 1.9 15.8 1.2 1.1 1.3 3.4 2.8 70.1 60.0 25.8 0.0 0.7 1.8 622.2 0.0 5.2 7.2 4.2 0.3 26.7 81.1 0.0 0.6 0.9 0.4 1.9 552.0 4.0 15.9 0.4 0.7 1.3 44.0 0.0 0.4 6081.9 2.0 30.2 12.6 9.2 0.9 21.6 8.8 15.9 0.9 0.4 1.0 0.5 0.2 3.9 253.6 0.0 2.1 13.8 413.5 1.2 11.0 2.0 59.2 0.5 1.1 0.5 2.4 0.4 6.8 0.4 5.6 0.9 191.4 164.1 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 FCHO1 KIAA0290 ENSG00000130475 "FCH and mu domain containing endocytic adaptor 1" O14526 19 17747718-17788568 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.5;lymphoid tissue: 24.3;skin 1: 22.2" "Cell type enhanced" "Detected in many" "B-cells: 16.8;dendritic cells: 19.1;Oligodendrocytes: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 62.4;RPMI-8226: 43.3;U-937: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041653, HPA062981" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA041653: AB_10795641, HPA062981: AB_2684915" "unprognostic (3.02e-1)" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (4.54e-3)" "unprognostic (3.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (5.48e-3)" "unprognostic (1.72e-9)" "unprognostic (3.76e-3)" "unprognostic (1.18e-1)" "unprognostic (2.21e-1)" "unprognostic (9.77e-3)" 2.2 1.8 24.9 14.7 33.7 20.2 1.5 21.7 32.6 1.0 8.6 2.5 3.2 1.3 1.4 1.1 1.5 4.2 0.8 24.1 25.6 1.4 2.2 3.7 24.3 27.5 28.6 1.7 0.7 1.1 3.9 1.1 29.7 1.0 2.2 3.4 1.3 0.8 0.6 22.2 8.1 1.7 19.9 15.5 3.4 4.4 29.2 17.6 1.0 0.8 17.4 3.0 1.0 59.5 0.9 11.9 7.5 5.2 0.2 0.2 7.5 1.1 0.3 0.3 0.5 1.5 1.4 62.4 17.1 0.5 1.4 2.3 3.7 2.3 0.2 27.6 2.1 4.9 1.4 6.4 0.6 15.7 10.2 0.1 0.3 0.0 0.4 0.4 1.6 30.2 24.9 28.9 0.0 17.4 36.2 27.8 3.6 14.7 28.7 30.2 0.2 43.3 0.2 1.2 1.3 2.5 0.3 5.9 0.9 0.9 6.0 15.4 1.3 0.1 4.1 0.9 0.4 18.2 9.0 33.4 0.9 38.5 0.5 13.2 9.6 10.1 7.0 14.3 6.0 12.4 7.9 6.3 14.5 12.3 7.4 6.1 37.8 6.4 11.5 15.3 7.6 7.4 24.9 33.7 21.7 32.6 24.1 25.6 27.5 28.6 29.7 19.9 29.2 59.5 0.4 0.0 1.5 0.7 16.8 0.0 0.4 0.2 0.6 7.8 2.0 4.3 0.9 2.8 0.4 1.8 0.0 2.9 19.1 2.0 0.0 0.5 1.5 0.8 0.2 2.4 1.2 2.5 15.0 0.0 4.6 2.5 1.5 1.0 9.5 2.9 2.5 0.0 6.8 0.0 13.0 1.7 0.0 8.7 14.3 0.7 2.5 11.0 1.8 6.5 12.3 0.1 13.4 3.0 46.9 2.1 0.5 8.6 4.5 0.3 0.1 0.1 0.7 0.8 0.0 0.2 0.6 0.9 5.5 0.2 0.6 0.8 9.8 12.2 1.8 0.3 FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 36.3" "Group enriched" "Detected in some" 5 "B-cells: 102.6;Early spermatids: 63.6;Plasma cells: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 5 "U-266/70: 3.4;U-698: 7.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 169000000 65000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.30e-3)" "unprognostic (3.51e-2)" "unprognostic (7.59e-3)" "unprognostic (1.57e-2)" "unprognostic (9.41e-3)" "unprognostic (4.32e-5)" "unprognostic (2.61e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-2)" "unprognostic (7.66e-3)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.51e-10)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.99e-2)" "unprognostic (2.78e-1)" 0.4 0.4 0.0 13.8 0.0 2.3 2.4 0.0 0.1 0.6 0.0 5.5 5.8 0.1 0.3 0.8 0.4 1.2 0.3 0.0 0.0 0.4 0.3 1.1 24.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 4.4 0.0 3.8 0.3 0.0 0.0 5.0 0.1 0.1 15.1 4.5 0.6 0.0 4.1 0.6 0.0 36.3 4.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.3 102.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 3.1 2.9 0.1 0.0 0.0 63.6 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.3 1.1 0.0 1.3 0.0 0.4 1.8 0.3 0.0 0.1 0.0 0.0 0.3 0.3 10.1 0.3 0.2 23.2 0.0 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.0 190.5 0.2 0.0 0.1 0.0 0.0 6.6 0.0 0.3 1.2 0.1 0.1 0.0 0.7 5.7 0.0 0.6 0.0 FCRLA "FCRL, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRLM1, FCRLX, FREB, MGC4595" ENSG00000132185 "Fc receptor like A" Q7L513 1 161706972-161714352 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 98.4" "Group enriched" "Detected in some" 6 "B-cells: 124.2;Melanocytes: 67.6" "Cancer enriched" "Detected in many" 21 "melanoma: 38.8" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 9 "memory B-cell: 368.0;naive B-cell: 341.5" "Lineage enriched" "Detected in many" 10 "B-cells: 368.0" "Group enriched" "Detected in some" 6 "Daudi: 484.1;SK-MEL-30: 197.8;U-698: 260.5" "Not detected" "Not detected" "Not detected" "Not detected" CAB016545 Enhanced "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "CAB016545: AB_2247037" "unprognostic (5.46e-4)" "unprognostic (7.19e-2)" "unprognostic (3.69e-3)" "unprognostic (4.75e-4)" "unprognostic (4.69e-2)" "unprognostic (1.48e-4)" "unprognostic (1.45e-2)" "unprognostic (4.15e-3)" "unprognostic (8.66e-2)" "unprognostic (3.58e-4)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (6.84e-5)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.56e-1)" "unprognostic (2.08e-2)" 0.8 0.2 0.5 23.5 0.3 4.1 0.5 1.1 0.7 0.3 0.3 2.6 0.9 0.4 0.6 0.5 0.1 1.1 0.6 0.4 0.2 0.3 0.4 0.6 68.5 0.3 0.3 0.2 0.0 0.0 0.0 0.3 0.3 0.8 2.8 0.3 2.3 0.1 0.3 1.2 19.1 0.4 0.1 38.5 4.1 0.2 0.5 7.7 0.5 0.3 98.4 3.4 0.1 0.4 0.7 0.0 0.0 0.0 0.4 0.4 0.0 2.7 7.4 0.2 0.5 0.0 0.0 484.1 0.2 7.0 0.0 0.1 0.0 0.7 0.8 1.8 0.0 0.5 0.0 0.0 0.0 0.2 2.0 0.4 0.5 2.4 0.4 0.1 0.0 0.0 0.9 26.7 0.1 0.0 0.1 0.3 0.1 0.0 0.1 4.0 8.3 52.4 0.0 0.1 0.0 0.0 0.3 0.1 197.8 0.0 0.0 0.2 0.5 0.6 0.7 0.5 0.5 0.7 0.3 260.5 2.9 0.3 44.3 0.4 0.3 0.2 0.8 0.0 0.1 368.0 0.2 0.4 0.4 341.5 0.2 0.1 0.6 0.2 0.2 38.4 0.2 17.0 0.5 0.3 1.1 0.7 0.4 0.2 0.3 0.3 0.3 0.1 0.5 0.4 0.0 0.0 0.6 0.0 124.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.7 67.6 0.0 0.4 0.0 1.0 0.5 0.1 0.3 0.1 0.0 14.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.4 0.0 1.6 0.0 0.1 0.0 FDPS ENSG00000160752 "Farnesyl diphosphate synthase" P14324 1 155308748-155320666 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Host-virus interaction, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 355.7" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 927.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 1187.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028200 Approved Approved Nucleoplasm,Cytosol NA NA 1500000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoplasm "HPA028200: AB_10612109" "unprognostic (1.23e-1)" "unprognostic (8.46e-3)" "unprognostic (2.47e-2)" "unprognostic (6.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.84e-2)" "prognostic unfavorable (7.35e-4)" "unprognostic (4.21e-2)" "unprognostic (6.78e-3)" "unprognostic (1.64e-3)" "unprognostic (7.19e-2)" "unprognostic (2.25e-2)" "unprognostic (1.11e-2)" "unprognostic (8.25e-2)" "unprognostic (2.07e-1)" "unprognostic (5.65e-2)" "unprognostic (8.44e-2)" 73.5 188.2 48.2 66.5 50.4 69.5 68.8 60.1 58.8 63.4 51.1 88.7 167.2 57.5 73.0 142.5 57.4 39.8 72.2 49.9 64.6 78.0 355.7 86.1 76.1 71.1 62.5 45.0 75.7 67.9 40.4 72.5 77.5 56.1 102.9 45.9 82.6 42.7 60.9 107.1 81.1 66.0 53.6 59.3 81.5 42.0 55.0 72.6 46.8 66.7 102.3 47.0 76.8 55.0 293.9 156.2 561.5 204.4 128.7 467.7 199.6 136.8 268.1 213.6 344.2 255.4 677.7 222.3 323.6 120.6 506.9 319.1 338.9 1187.5 198.9 122.4 242.5 129.4 260.1 311.5 210.8 212.1 142.0 335.5 184.6 339.6 168.8 96.4 377.6 322.3 235.1 579.9 225.3 315.1 273.6 205.0 338.9 216.4 225.5 231.6 243.2 620.0 567.7 193.0 217.4 185.6 140.7 253.0 243.0 317.3 182.6 567.6 277.1 118.4 144.3 74.3 254.9 244.3 202.3 401.1 115.3 221.7 191.1 90.6 85.5 124.1 89.2 92.9 79.7 102.8 77.8 91.1 95.6 95.1 69.9 87.1 38.9 115.2 70.0 76.2 113.7 134.7 48.2 50.4 60.1 58.8 49.9 64.6 71.1 62.5 77.5 53.6 55.0 55.0 154.2 73.7 181.6 38.5 68.4 36.8 83.3 927.7 42.1 69.4 84.6 56.9 1.8 97.2 431.5 53.3 62.6 207.8 74.9 343.0 137.0 180.9 216.6 56.7 38.2 161.9 71.4 133.4 30.8 329.9 198.7 59.8 52.0 77.8 62.8 116.6 168.1 361.9 112.0 55.5 28.1 135.7 299.1 54.8 44.4 67.9 60.9 52.8 96.0 15.0 144.7 81.1 87.6 22.6 39.7 256.7 324.3 70.3 91.3 206.1 194.1 145.0 129.6 90.8 72.3 47.0 177.5 42.0 14.2 49.7 59.8 143.5 68.3 230.6 165.4 148.2 FDXR "ADR, ADXR" ENSG00000161513 "Ferredoxin reductase" P22570 17 74862497-74873031 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "adrenal gland: 343.1" "Group enriched" "Detected in many" 7 "Granulosa cells: 329.3;Theca cells: 794.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 89.5;Hep G2: 173.5" "Low region specificity" "Detected in all" "CAB008597, CAB009818, HPA044393, HPA053673" Enhanced Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 52: Non-specific - Transcription" Mitochondria "CAB008597: AB_1615557, CAB009818: AB_2102601, HPA044393: AB_2678927, HPA053673: AB_2682225" "unprognostic (2.69e-2)" "unprognostic (1.17e-3)" "unprognostic (7.51e-2)" "prognostic favorable (2.38e-4)" "unprognostic (3.43e-2)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" "unprognostic (1.68e-2)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (6.30e-2)" "unprognostic (1.42e-2)" "unprognostic (1.19e-2)" "unprognostic (4.50e-2)" "unprognostic (4.03e-2)" "unprognostic (2.13e-1)" 3.9 343.1 6.9 2.4 8.4 2.2 3.8 7.8 8.1 7.8 8.6 9.7 4.6 6.7 5.1 26.0 12.9 4.1 6.0 6.6 6.7 6.5 14.9 5.3 2.9 7.6 7.9 20.5 12.9 5.9 4.1 3.0 7.5 6.7 3.2 0.5 7.1 4.4 7.7 16.4 5.6 2.3 7.4 33.9 7.6 45.6 7.0 4.7 6.0 1.7 2.5 6.2 10.5 7.5 12.5 65.6 9.6 10.8 6.8 9.1 89.5 14.8 15.9 8.6 17.1 18.3 10.8 29.6 2.6 6.2 4.8 24.9 6.9 18.4 2.5 27.9 15.2 22.6 10.6 173.5 19.0 5.0 75.1 29.2 20.3 9.1 3.1 7.0 43.9 10.9 36.1 4.8 13.4 53.4 19.7 10.6 5.5 11.8 14.5 10.6 16.4 16.2 7.1 21.0 5.2 12.1 10.0 21.7 11.2 10.9 47.4 4.7 20.5 5.9 51.9 9.4 7.4 12.7 2.3 6.5 16.1 7.7 20.6 1.7 6.0 5.0 5.6 4.5 5.0 4.8 5.1 6.8 7.3 2.4 4.4 5.4 2.0 10.3 3.4 1.4 15.4 5.2 6.9 8.4 7.8 8.1 6.6 6.7 7.6 7.9 7.5 7.4 7.0 7.5 4.0 3.2 3.9 7.5 8.2 9.7 17.8 42.6 17.1 4.9 6.6 8.4 3.8 5.7 23.3 9.2 4.2 53.2 2.8 18.6 5.9 11.1 6.5 28.2 4.3 4.6 7.1 4.0 1.4 7.9 18.9 12.9 13.7 3.5 5.7 329.3 12.5 13.9 23.1 3.3 2.2 13.1 36.7 6.2 2.7 14.9 5.9 4.6 5.4 1.0 3.9 11.4 8.2 3.0 1.3 9.0 16.9 4.5 7.1 5.2 24.9 21.7 73.6 5.1 0.0 6.2 18.3 6.3 6.1 33.7 18.2 46.1 8.6 794.1 20.3 17.4 FERMT1 "C20orf42, FLJ20116, KIND1, UNC112A, URP1" ENSG00000101311 "Fermitin family member 1" Q9BQL6 20 6074845-6123030 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 121.3;Oligodendrocyte precursor cells: 229.7;Pancreatic endocrine cells: 384.1;Undifferentiated cells: 95.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 84.3;HaCaT: 95.4;HBEC3-KT: 100.2;OE19: 75.1;RT4: 54.4" "Region enriched" "Detected in single" 5 "hippocampal formation: 2.0" "Not detected" "Not detected" "HPA039778, HPA041966" Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA039778: AB_10805593, HPA041966: AB_10795387" "unprognostic (1.08e-3)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "unprognostic (3.64e-3)" "unprognostic (1.75e-3)" "unprognostic (2.82e-1)" "unprognostic (9.49e-2)" "unprognostic (1.53e-3)" "unprognostic (2.13e-1)" "unprognostic (1.83e-1)" "prognostic unfavorable (6.60e-4)" "unprognostic (4.38e-2)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (2.04e-1)" "unprognostic (4.60e-2)" "unprognostic (5.33e-2)" 0.6 11.4 1.4 9.3 2.2 0.3 1.5 1.5 1.4 2.1 0.0 24.6 14.8 2.3 0.8 12.8 3.5 2.6 1.0 1.6 2.0 4.0 0.3 1.0 0.0 3.1 2.8 4.2 2.7 12.5 0.2 4.8 3.2 5.0 35.8 0.0 1.9 4.3 0.1 17.6 11.0 2.0 2.6 0.4 13.0 0.5 2.2 2.4 2.9 0.3 5.1 6.8 3.4 3.4 53.4 14.4 0.0 0.0 0.4 5.0 18.5 2.8 0.1 1.9 0.8 24.8 84.3 0.0 14.1 2.9 6.3 95.4 36.8 100.2 2.0 0.0 2.6 8.2 10.7 26.8 1.2 0.0 2.5 4.8 43.6 11.5 24.0 0.4 1.2 0.3 0.0 0.2 2.4 1.4 0.0 2.4 11.5 75.1 41.1 0.0 12.5 29.9 9.9 54.4 7.7 0.9 8.8 0.3 0.0 0.7 8.4 2.2 0.4 5.1 3.4 0.7 39.5 0.2 0.1 0.1 3.7 9.5 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 1.5 1.4 1.6 2.0 3.1 2.8 3.2 2.6 2.2 3.4 0.1 0.0 0.6 0.3 0.0 41.4 51.5 44.8 121.3 0.0 3.4 16.3 1.3 8.6 16.0 0.0 0.0 65.0 0.1 61.2 1.9 34.5 0.1 4.0 31.8 0.6 15.6 8.4 2.3 40.3 31.3 7.5 46.9 2.0 0.0 13.5 0.4 0.4 4.9 0.0 2.2 49.0 2.0 0.0 0.8 1.1 10.8 1.5 1.8 7.5 0.1 0.0 0.0 229.7 0.5 384.1 23.5 3.0 1.4 20.1 13.9 15.8 5.7 0.0 0.0 6.2 2.9 0.2 0.6 80.6 43.0 7.3 1.0 6.2 95.2 44.8 FEZ2 ENSG00000171055 "Fasciculation and elongation protein zeta 2" Q9UHY8 2 36531805-36646087 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035978 Uncertain Approved "Nucleoli,Nucleoli rim,Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" "Golgi apparatus, Cytosol" "HPA035978: AB_10672235" "unprognostic (1.42e-1)" "unprognostic (5.02e-3)" "unprognostic (2.89e-1)" "unprognostic (1.15e-2)" "unprognostic (2.91e-2)" "unprognostic (1.94e-3)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.09e-1)" "unprognostic (7.05e-2)" "unprognostic (2.42e-1)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (6.65e-2)" "unprognostic (7.82e-3)" "unprognostic (7.07e-2)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" 53.0 39.1 48.2 21.0 51.6 16.5 35.9 48.2 68.6 26.9 42.8 34.5 22.1 33.1 18.9 31.7 23.8 23.6 46.7 49.2 48.4 33.6 29.4 27.1 24.3 49.5 46.3 27.6 10.8 20.3 14.2 46.8 48.2 23.5 27.9 26.5 17.1 32.5 108.1 17.0 28.5 41.1 50.1 30.3 21.9 20.8 49.6 18.2 23.9 78.5 19.5 29.1 24.3 56.3 64.9 37.1 49.4 22.3 91.3 122.1 39.5 157.1 76.5 90.7 56.0 24.6 21.5 39.1 94.7 199.2 41.0 25.1 42.4 54.3 98.5 9.3 24.7 31.7 12.2 43.5 44.4 32.9 8.5 119.9 44.2 57.8 69.6 61.2 131.0 9.5 35.4 12.0 170.2 22.7 19.6 27.5 27.1 33.9 57.8 16.9 44.3 14.0 72.9 57.6 1.9 45.7 38.7 31.9 37.8 51.7 11.3 39.1 161.2 59.7 32.9 33.4 92.9 9.8 11.5 26.6 58.9 22.4 84.8 2.5 3.5 5.1 1.7 3.4 1.0 1.6 1.3 1.0 3.5 1.0 1.5 0.7 4.2 3.2 2.3 15.6 1.4 0.8 48.2 51.6 48.2 68.6 49.2 48.4 49.5 46.3 48.2 50.1 49.6 56.3 109.4 54.5 37.5 25.8 23.7 31.4 94.7 45.5 41.5 52.5 31.7 33.1 43.1 17.2 70.2 58.8 45.9 96.4 61.1 57.6 56.7 80.3 5.6 38.4 44.7 100.9 24.0 15.3 45.4 30.6 87.6 50.7 27.0 64.3 24.1 66.0 97.5 37.2 93.7 21.9 22.9 28.8 38.7 88.1 65.4 10.7 54.3 64.6 56.9 45.0 56.0 97.1 35.0 23.1 50.5 74.4 41.4 66.2 17.9 99.1 65.6 45.1 35.9 36.3 59.2 64.0 51.2 12.1 34.9 24.0 32.1 180.1 24.2 47.2 37.7 140.6 FGF1 "AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1" ENSG00000113578 "Fibroblast growth factor 1" P05230 5 142592178-142698070 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 295.2;choroid plexus: 125.8" "Cell type enhanced" "Detected in many" "Astrocytes: 75.1;Cardiomyocytes: 62.4;Muller glia cells: 69.4;Oligodendrocytes: 119.8" "Cancer enriched" "Detected in many" 12 "glioma: 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.6;BJ hTERT+: 33.0;BJ hTERT+ SV40 Large T+: 35.9;BJ hTERT+ SV40 Large T+ RasG12V: 45.0;HBF TERT88: 64.3;hTEC/SVTERT24-B: 45.4;LHCN-M2: 30.6;U-2 OS: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003265, CAB017519" Enhanced Supported Nucleoplasm "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB017519: AB_629473, HPA003265: AB_1848522" "unprognostic (1.25e-2)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (2.55e-2)" "unprognostic (3.52e-1)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.63e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.54e-1)" "prognostic favorable (2.59e-5)" "unprognostic (3.72e-4)" "unprognostic (2.49e-1)" "prognostic favorable (3.45e-5)" "unprognostic (3.01e-4)" 17.9 3.3 206.3 1.6 259.3 1.1 12.5 213.9 295.2 1.3 125.8 2.4 1.0 3.1 7.9 2.0 1.7 2.5 50.2 183.5 245.5 66.5 1.7 2.8 1.2 236.2 237.7 0.9 0.8 4.3 6.5 2.1 259.9 1.8 1.3 18.8 7.3 2.3 2.2 1.7 1.2 2.5 225.4 6.9 0.8 2.0 244.3 1.5 5.6 7.8 2.0 1.2 1.0 272.8 5.6 0.3 0.3 1.5 1.1 3.3 1.8 44.6 33.0 35.9 45.0 0.2 0.2 1.3 3.1 15.4 2.1 0.7 0.0 3.5 64.3 0.2 0.0 0.0 0.8 0.4 0.6 0.0 0.4 1.6 1.1 45.4 2.7 9.7 0.0 0.2 0.0 1.6 30.6 0.7 0.1 0.9 1.4 0.1 1.4 0.2 1.5 0.6 1.5 0.2 1.1 2.3 0.1 0.9 0.6 8.0 0.0 0.2 1.1 5.8 33.0 0.8 21.3 0.8 0.4 0.3 8.2 0.3 1.6 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.3 0.3 0.0 0.1 0.2 0.1 0.0 206.3 259.3 213.9 295.2 183.5 245.5 236.2 237.7 259.9 225.4 244.3 272.8 1.4 0.0 0.0 75.1 0.1 0.4 5.0 5.7 7.4 3.5 1.2 25.4 62.4 0.0 2.1 20.2 16.7 1.1 0.1 0.0 0.0 1.1 0.4 0.0 0.7 4.8 0.0 0.0 13.0 0.0 0.5 4.7 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 14.6 0.0 12.2 0.0 0.0 1.4 0.0 0.2 3.6 29.0 0.0 69.4 0.0 15.1 119.8 0.6 0.0 0.4 0.0 5.3 0.0 0.3 0.1 11.6 6.6 0.5 23.4 0.1 0.1 0.6 0.0 0.8 0.4 0.0 0.0 0.7 FGF22 ENSG00000070388 "Fibroblast growth factor 22" Q9HCT0 19 639879-644371 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;skin 1: 13.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.4;Horizontal cells: 13.5;Muller glia cells: 4.7;Rod photoreceptor cells: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (2.84e-3)" "unprognostic (1.04e-2)" "unprognostic (1.17e-1)" "unprognostic (5.25e-4)" "unprognostic (1.16e-1)" "unprognostic (3.66e-3)" "unprognostic (2.85e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-4)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (3.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.31e-1)" "unprognostic (8.36e-2)" 0.5 0.3 2.6 0.0 2.8 0.0 0.6 2.4 4.9 0.7 1.3 0.6 0.2 0.6 0.0 0.5 1.0 0.0 0.3 2.5 2.1 0.4 0.2 0.3 0.0 2.6 2.6 2.9 0.2 0.0 0.6 0.0 2.7 1.1 0.0 0.1 0.6 0.1 0.7 13.5 0.4 0.0 1.8 0.2 0.6 1.1 2.9 0.0 0.2 0.0 0.0 0.9 0.9 3.0 0.2 0.3 0.1 1.9 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.1 0.6 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.7 0.0 0.0 0.3 0.1 0.2 0.4 0.7 0.5 0.0 0.1 0.0 0.3 0.1 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.1 0.1 0.2 0.1 0.0 0.1 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.8 2.4 4.9 2.5 2.1 2.6 2.6 2.7 1.8 2.9 3.0 0.6 3.2 0.0 1.0 0.6 0.8 1.3 0.0 0.0 8.4 0.5 0.6 1.4 1.5 0.1 0.0 0.0 0.4 1.2 0.6 0.0 0.1 0.6 0.6 0.6 0.5 0.0 0.4 1.6 0.0 0.4 1.1 0.0 1.0 0.0 0.5 0.7 0.4 0.2 13.5 0.9 0.5 0.0 0.0 1.0 0.2 0.3 0.1 1.8 0.0 0.2 4.7 0.0 0.0 1.6 0.4 0.1 0.0 0.7 1.5 0.8 0.5 0.2 6.4 0.0 1.9 0.9 1.1 2.0 0.0 1.0 3.4 1.6 0.2 0.5 0.6 FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 63.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 216.6;Leydig cells: 83.3;Proximal tubular cells: 53.4;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 112.1;ASC TERT1: 66.1;BJ: 45.6;fHDF/TERT166: 50.3;HSkMC: 84.8;RH-30: 119.7;U-138 MG: 56.5" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" 43.8 4.5 3.4 31.5 3.9 0.1 8.5 4.2 5.2 29.4 2.1 11.1 3.7 29.2 4.3 9.5 15.4 46.0 10.5 3.3 4.8 4.5 1.4 12.9 8.3 4.6 4.6 13.4 2.2 3.6 2.2 23.5 5.1 16.2 9.6 8.4 5.1 12.0 2.2 2.6 3.6 26.9 4.1 1.8 5.5 2.3 4.5 3.0 7.4 23.8 4.8 63.3 10.3 4.5 0.2 0.0 0.2 0.3 112.1 66.1 0.1 45.6 25.7 0.0 0.1 0.0 0.3 0.2 0.2 50.3 0.4 0.9 0.0 0.3 0.0 0.1 0.2 0.0 0.5 0.0 10.6 0.3 0.1 84.8 0.8 9.4 0.0 0.3 0.0 0.0 0.1 0.3 5.4 0.1 0.0 0.1 0.2 0.1 0.3 0.1 119.7 0.1 0.1 0.1 1.8 0.6 0.4 0.0 0.4 0.2 0.2 0.2 0.2 56.5 0.5 1.1 0.2 0.5 0.4 0.0 13.3 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.9 4.2 5.2 3.3 4.8 4.6 4.6 5.1 4.1 4.5 4.5 16.1 12.8 19.3 2.0 2.2 14.4 16.8 1.3 1.2 7.9 11.1 9.5 46.8 7.2 0.5 9.2 2.1 6.2 3.2 0.2 119.3 2.0 3.3 8.8 46.2 5.2 0.0 2.7 1.9 0.6 3.3 216.6 2.0 29.2 1.3 0.6 1.8 2.7 2.0 3.3 3.3 0.0 2.0 1.6 15.9 4.0 83.3 1.9 7.2 1.0 0.2 9.8 2.1 1.5 2.9 0.6 0.0 4.9 0.7 9.4 0.0 53.4 0.3 6.1 6.6 43.6 71.6 0.6 0.7 1.8 12.6 2.9 2.9 2.9 0.1 8.4 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 207.8;lung: 86.5;lymphoid tissue: 141.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 182.2;Langerhans cells: 63.8;Macrophages: 155.9;monocytes: 159.7;NK-cells: 259.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Daudi: 86.0;U-266/70: 153.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" 25.0 6.8 12.8 62.2 11.9 207.8 16.0 11.9 19.1 7.6 11.5 6.0 3.9 8.1 1.7 5.2 15.6 12.7 8.7 11.4 12.3 7.5 10.8 86.5 27.5 13.6 12.7 2.9 5.8 1.6 2.7 7.9 14.5 7.2 4.0 0.7 6.6 2.4 3.2 4.5 10.1 16.3 12.5 141.1 5.9 2.5 17.2 8.4 7.4 6.5 20.0 17.8 7.3 12.6 0.0 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 86.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 1.7 29.3 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 3.8 5.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 153.1 2.1 6.5 0.0 19.5 0.0 30.8 381.4 229.4 189.5 469.1 11.3 54.0 15.8 89.1 196.1 84.0 8.0 78.4 272.9 264.5 405.2 9.0 1.2 494.1 12.8 11.9 11.9 19.1 11.4 12.3 13.6 12.7 14.5 12.5 17.2 12.6 8.6 6.4 20.0 0.0 24.9 2.8 0.6 0.2 0.0 0.0 0.4 0.6 1.6 1.5 5.7 1.8 0.0 0.5 55.2 0.0 0.0 0.0 0.3 0.1 0.2 14.9 0.0 7.4 0.2 0.2 0.7 2.7 1.5 0.1 13.3 0.1 6.8 1.9 56.8 0.0 0.1 0.0 0.0 182.2 63.8 0.7 0.3 155.9 1.8 6.5 159.7 0.1 259.5 1.0 0.4 0.0 1.2 0.0 4.2 0.4 0.0 0.7 1.5 0.0 0.0 0.7 0.6 0.2 0.5 0.5 1.1 1.0 28.0 0.0 0.0 2.5 FHL5 "ACT, dJ393D12.2, FLJ33049" ENSG00000112214 "Four and a half LIM domains 5" Q5TD97 6 96562548-96616636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.5" "Group enriched" "Detected in some" 20 "Early spermatids: 1160.3;Late spermatids: 1540.1" "Cancer enhanced" "Detected in many" "renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "ASC diff: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "prognostic favorable (4.81e-4)" "unprognostic (4.93e-2)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.84e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.22e-1)" "unprognostic (3.48e-3)" 35.7 10.3 5.4 4.4 8.5 0.0 16.0 5.8 7.5 27.8 6.2 5.8 2.5 15.0 17.6 9.6 21.5 12.9 5.6 4.9 5.3 6.4 0.4 14.0 1.8 6.3 5.8 11.4 4.6 3.3 1.2 0.6 7.1 4.9 5.0 0.4 2.1 11.1 8.9 5.5 5.1 9.6 5.4 3.5 4.0 65.5 7.2 1.2 8.9 14.6 0.8 6.8 10.3 5.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 8.5 5.8 7.5 4.9 5.3 6.3 5.8 7.1 5.4 7.2 5.5 5.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1160.3 0.0 0.1 3.8 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1540.1 52.5 1.1 5.4 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.2 0.0 0.0 0.0 0.0 52.6 1.9 67.4 13.2 4.4 0.0 0.3 0.0 0.6 0.1 0.0 0.2 FITM2 "C20orf142, dJ881L22.2, FIT2" ENSG00000197296 "Fat storage inducing transmembrane protein 2" Q8N6M3 20 44302840-44311202 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 67.4" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 153.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (2.92e-2)" "unprognostic (7.61e-2)" "unprognostic (2.27e-2)" "unprognostic (2.10e-3)" "unprognostic (1.02e-1)" "unprognostic (3.57e-3)" "unprognostic (1.63e-2)" "unprognostic (3.90e-2)" "unprognostic (8.43e-2)" "unprognostic (5.19e-2)" "unprognostic (6.56e-3)" "unprognostic (1.19e-1)" "prognostic favorable (8.98e-12)" "unprognostic (2.07e-1)" "unprognostic (2.54e-1)" "unprognostic (3.38e-3)" "unprognostic (2.49e-3)" 11.4 11.1 4.8 2.9 5.0 1.2 7.0 5.7 6.3 4.2 5.9 5.2 4.3 4.0 8.7 3.3 3.7 3.2 67.4 4.8 5.9 7.9 6.4 4.1 2.2 6.9 5.9 4.6 7.4 13.6 5.2 1.9 7.4 6.4 6.0 6.7 6.5 4.4 9.2 5.7 3.9 5.3 4.2 2.6 4.6 3.8 5.4 1.7 6.3 16.8 2.6 4.5 3.1 4.7 7.2 10.9 4.5 6.6 31.4 12.8 4.6 11.5 8.4 8.9 4.9 13.5 5.1 4.9 6.5 13.0 14.3 15.8 5.7 7.7 9.6 1.4 2.7 1.6 6.5 22.9 6.6 3.1 4.0 9.7 17.2 6.2 4.7 4.9 6.4 3.1 2.7 14.2 9.1 22.4 1.2 3.4 1.1 10.8 13.9 1.9 8.4 4.9 5.1 6.7 2.7 3.2 24.4 13.5 10.3 2.0 16.5 2.4 7.9 28.2 12.6 16.6 6.8 5.2 14.4 1.3 12.6 4.9 14.4 0.7 1.0 0.6 1.1 1.0 1.2 0.6 1.2 0.9 1.0 0.6 2.0 1.6 0.4 1.4 0.8 0.6 1.2 0.9 4.8 5.0 5.7 6.3 4.8 5.9 6.9 5.9 7.4 4.2 5.4 4.7 2.8 6.4 9.7 1.3 3.6 6.9 3.5 2.8 1.2 6.4 5.0 3.4 153.9 11.5 4.3 5.5 6.2 2.0 1.0 5.1 1.9 5.2 4.6 2.2 5.0 4.4 9.1 0.8 2.3 8.6 3.5 9.4 4.1 2.1 0.0 4.4 8.2 14.1 3.4 6.7 2.1 4.8 0.0 3.8 2.2 1.2 7.8 1.7 7.2 1.0 2.3 6.6 2.1 4.0 0.9 5.7 4.1 7.5 3.1 3.1 5.9 6.2 4.0 5.9 0.0 5.6 6.3 9.1 6.0 2.7 8.1 1.5 2.1 16.3 9.2 2.2 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FLG ENSG00000143631 Filaggrin P20930 1 152302165-152325239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 458.2" "Cell type enriched" "Detected in some" 13 "Suprabasal keratinocytes: 44.0" "Cancer enriched" "Detected in some" 7 "melanoma: 11.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.1;NTERA-2: 3.1;TIME: 2.1;U-2 OS: 2.4;U-2197: 2.6;WM-115: 2.0" "Not detected" "Not detected" "CAB002210, HPA027505, HPA030188, HPA030189" Enhanced Enhanced "Cytoplasmic bodies" NA NA 3800000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Cytoplasmic bodies" "CAB002210: AB_563731, HPA027505: AB_10600107, HPA030188: AB_10601749, HPA030189: AB_10601999" "unprognostic (3.37e-2)" "unprognostic (3.76e-1)" "unprognostic (8.83e-2)" "unprognostic (2.96e-3)" "unprognostic (9.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" "unprognostic (4.03e-2)" "unprognostic (1.12e-1)" "unprognostic (9.98e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" "unprognostic (1.45e-1)" "unprognostic (4.28e-2)" "unprognostic (4.15e-2)" "unprognostic (7.41e-3)" 0.3 0.4 0.7 0.1 0.3 0.1 15.7 0.3 0.4 6.5 0.0 0.2 0.0 0.5 0.0 12.0 0.4 0.1 0.4 0.3 1.4 0.4 0.2 0.2 0.0 1.6 0.9 0.9 0.4 0.0 0.2 0.0 1.2 0.2 0.0 0.2 2.7 0.0 1.8 458.2 0.1 0.0 0.8 0.1 0.2 0.3 0.8 0.5 0.3 0.0 0.5 0.1 4.9 0.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.0 10.1 0.0 0.0 0.0 1.1 0.0 0.8 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 2.1 0.8 2.4 2.6 1.9 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.3 0.4 0.3 1.4 1.6 0.9 1.2 0.8 0.8 0.6 0.0 0.0 0.0 0.0 0.0 3.2 0.0 1.0 0.0 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.0 44.0 0.0 0.1 0.1 0.0 0.0 FLG2 IFPS ENSG00000143520 "Filaggrin family member 2" Q5D862 1 152348735-152360006 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 483.9" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 24.2" "Cancer enriched" "Detected in some" 8 "melanoma: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA028699 Approved NA NA 21000000 "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA028699: AB_10601905" "unprognostic (2.58e-1)" "unprognostic (2.33e-1)" "unprognostic (3.08e-1)" "unprognostic (6.85e-2)" "unprognostic (6.59e-3)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" "unprognostic (2.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.96e-1)" 0.3 0.0 0.1 0.0 0.0 0.1 32.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 483.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.9 0.4 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.1 1.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 1.1 0.0 1.0 0.2 0.1 0.2 0.0 24.2 0.0 0.0 0.1 0.0 0.3 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 FLNC "ABP-280, ABPL, FLN2" ENSG00000128591 "Filamin C" Q14315 7 128830406-128859274 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 635.2;skeletal muscle: 1384.8;tongue: 442.6" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 1892.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 393.6;fHDF/TERT166: 180.2;hTEC/SVTERT24-B: 190.6;U-2 OS: 163.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006135, HPA071007" Enhanced Supported "Plasma membrane,Cytosol" NA NA 26000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA006135: AB_1848602, HPA071007: " "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" "unprognostic (4.47e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (1.64e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (2.17e-5)" "unprognostic (1.03e-3)" "unprognostic (2.35e-2)" "unprognostic (1.35e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (5.68e-3)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (3.73e-5)" 13.1 3.4 5.8 25.9 11.5 0.0 5.9 11.5 9.9 16.9 3.0 215.4 9.4 96.6 4.6 40.3 35.4 13.8 635.2 5.9 16.7 2.8 1.1 12.5 0.6 52.1 11.1 9.4 2.1 3.2 1.6 2.4 29.9 71.1 9.8 0.5 16.5 100.7 1384.8 8.9 40.3 114.4 51.7 0.7 65.6 2.2 19.1 0.3 4.3 442.6 0.2 162.7 21.3 49.8 0.1 0.8 4.2 0.1 34.4 41.2 4.1 393.6 73.6 109.2 52.3 124.0 1.0 0.1 64.7 180.2 44.9 0.1 23.7 0.9 64.4 0.2 13.1 0.1 20.2 0.1 43.2 0.0 0.2 78.0 0.1 190.6 0.1 44.2 69.0 0.3 49.0 0.2 75.8 0.0 0.0 1.5 64.5 0.1 22.6 0.1 127.5 1.0 0.1 0.0 2.1 7.0 0.7 0.1 0.3 88.0 0.4 1.6 144.6 38.2 163.5 10.1 0.2 0.1 0.0 0.3 129.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 11.5 11.5 9.9 5.9 16.7 52.1 11.1 29.9 51.7 19.1 49.8 3.6 3.2 0.5 0.7 0.0 3.7 0.3 0.1 1.2 0.6 0.3 1.3 1892.3 0.0 1.9 1.8 0.0 0.4 0.2 0.5 0.0 0.7 0.4 1.8 5.0 31.4 0.0 0.0 0.2 0.2 3.0 31.6 0.0 2.9 0.0 0.6 1.8 0.0 0.9 0.0 1.1 0.3 0.0 0.0 6.9 0.9 5.3 0.5 5.4 0.0 0.0 0.1 0.0 0.0 5.8 2.6 0.1 10.5 1.2 2.7 0.0 1.1 0.0 0.2 0.0 71.8 38.1 0.3 1.0 0.2 4.5 1.9 1.0 0.1 0.2 1.0 FLOT1 ENSG00000137312 "Flotillin 1" O75955 6 30727709-30742732 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 314.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 423.3;hTERT-RPE1: 242.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001393, CAB007766" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Vesicles, Plasma membrane" "CAB007766: AB_562116, HPA001393: AB_1078892" "unprognostic (2.68e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (3.41e-3)" "unprognostic (2.68e-3)" "unprognostic (1.86e-1)" "unprognostic (2.65e-1)" "prognostic favorable (3.06e-4)" "unprognostic (1.81e-2)" "unprognostic (9.36e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (6.43e-3)" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (2.46e-2)" 141.7 239.5 49.3 27.9 54.6 41.7 129.8 49.4 60.9 111.1 56.8 150.3 28.7 108.9 8.4 81.8 95.8 23.1 234.5 55.1 57.9 146.1 127.3 136.8 22.1 50.9 51.5 84.1 88.5 41.4 102.5 35.0 57.4 109.6 17.7 6.3 99.1 45.8 190.0 51.7 87.1 33.0 45.8 129.6 96.9 65.0 53.6 24.9 111.7 83.1 17.0 134.5 96.9 48.8 54.3 18.3 46.4 62.0 49.1 71.0 1.3 59.7 67.5 82.8 79.3 19.4 30.0 13.0 29.0 101.3 423.3 41.8 35.0 20.1 28.6 36.1 1.3 41.1 17.5 19.1 119.2 12.2 67.0 75.4 30.6 40.9 71.3 242.7 65.9 37.9 21.7 52.7 77.9 22.9 38.0 14.5 15.1 29.4 15.7 20.2 48.4 38.0 30.3 13.0 16.4 17.2 33.7 28.7 164.6 30.4 43.8 10.1 44.0 199.5 37.6 20.6 120.6 18.6 19.7 28.8 26.2 42.6 122.7 179.3 76.9 132.0 35.0 38.9 24.1 28.0 21.3 30.4 58.9 23.0 23.7 27.4 314.3 79.9 26.3 59.2 3.9 58.3 49.3 54.6 49.4 60.9 55.1 57.9 50.9 51.5 57.4 45.8 53.6 48.8 175.4 89.8 77.0 26.1 38.1 28.7 111.5 44.9 80.2 14.7 72.1 73.4 90.6 62.9 59.2 84.6 6.2 82.2 57.7 103.2 123.3 77.6 60.2 73.9 50.1 141.6 68.8 41.7 41.3 85.9 70.7 67.6 55.5 75.2 143.3 41.4 154.9 59.7 130.6 20.2 40.2 66.6 57.0 61.3 84.9 144.1 61.8 89.4 71.2 28.1 99.2 64.7 68.0 27.2 22.7 65.7 112.0 38.0 60.4 69.5 89.0 172.1 80.7 18.1 52.6 58.1 65.9 80.2 26.7 63.7 26.9 61.6 51.2 29.1 83.2 99.4 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FMNL2 "FHOD2, KIAA1902" ENSG00000157827 "Formin like 2" Q96PY5 2 152335174-152649826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 223.5" "Cell type enhanced" "Detected in many" "Astrocytes: 668.0;Excitatory neurons: 574.9;Inhibitory neurons: 321.9;Oligodendrocyte precursor cells: 371.0;Oligodendrocytes: 2442.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 5 "monocytes: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 191.4;hTERT-HME1: 123.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005464 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Golgi apparatus, Plasma membrane" "HPA005464: AB_1848965" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (8.75e-3)" "unprognostic (3.06e-2)" "unprognostic (7.40e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (2.54e-1)" "unprognostic (4.66e-2)" "unprognostic (5.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.58e-1)" "unprognostic (3.73e-2)" "unprognostic (1.58e-1)" 26.4 25.2 88.9 11.1 152.3 0.7 20.8 135.2 119.3 18.1 73.6 15.2 8.9 20.7 14.9 8.5 15.3 16.8 12.0 92.9 102.6 22.2 8.1 32.2 14.2 172.3 136.3 54.0 18.1 23.1 28.4 58.2 165.5 15.2 12.3 10.6 32.1 11.7 24.1 11.3 11.6 16.3 121.6 19.8 17.3 9.0 128.5 14.8 33.1 19.3 8.4 19.3 18.3 223.5 14.5 15.1 45.9 25.5 54.5 58.3 191.4 14.4 29.4 24.9 34.8 16.3 0.9 0.3 29.8 12.6 53.7 16.2 22.4 45.8 39.6 0.1 23.4 0.2 10.0 70.2 15.7 4.0 0.8 38.4 27.8 48.2 123.5 48.3 44.7 6.6 0.6 0.3 13.9 4.0 0.8 4.5 29.5 12.4 30.0 25.9 9.9 20.9 72.9 9.9 46.6 38.0 12.2 4.5 51.4 38.7 1.1 1.5 49.9 37.4 1.0 12.7 25.0 1.3 0.5 0.1 34.7 3.3 77.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 88.9 152.3 135.2 119.3 92.9 102.6 172.3 136.3 165.5 121.6 128.5 223.5 21.5 25.6 25.9 668.0 2.7 26.4 23.0 14.0 19.4 23.8 11.4 10.0 3.8 1.5 16.4 11.0 0.0 36.1 4.5 2.6 13.7 20.4 24.5 14.1 10.8 29.1 8.3 0.4 574.9 6.9 17.8 36.2 8.2 27.0 1.3 36.0 20.0 1.3 40.6 0.0 321.9 3.3 10.2 64.8 53.0 10.5 35.1 31.5 7.2 245.4 4.4 3.9 1.0 371.0 2442.0 10.0 2.1 41.3 5.6 33.5 0.7 8.9 8.5 2.0 6.6 18.7 13.2 6.7 8.0 6.3 16.9 27.0 2.1 13.0 6.1 13.2 FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 683.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 64.2;Cholangiocytes: 133.0;Hepatocytes: 265.4;Proximal enterocytes: 108.8;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "Hep G2: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" 3.1 5.7 2.0 5.1 2.9 2.0 46.1 3.9 2.8 7.8 0.5 41.3 71.3 2.8 6.9 1.2 3.6 15.8 3.1 2.1 2.4 51.5 683.3 27.1 4.0 4.2 2.9 4.1 48.1 68.3 6.7 2.4 4.8 9.7 46.6 0.9 32.7 4.0 0.8 11.6 73.9 3.5 3.2 4.0 120.1 5.2 3.1 1.1 2.0 1.4 2.5 3.9 1.5 5.6 0.1 1.1 0.6 0.1 2.8 0.8 0.9 0.7 0.5 0.3 0.8 0.7 2.4 0.4 0.8 0.8 0.2 0.4 0.0 0.0 0.0 1.4 0.2 1.6 0.1 41.7 0.9 1.4 9.0 1.3 0.2 0.4 0.0 0.4 0.6 0.2 0.1 0.1 1.5 1.4 0.2 0.7 2.8 5.3 0.8 0.4 0.5 0.4 3.4 0.6 0.5 0.3 0.9 2.8 1.3 1.3 2.1 10.4 1.1 0.0 0.3 0.9 0.0 0.3 0.0 0.3 1.1 0.5 0.3 7.0 12.9 4.1 2.0 5.9 0.3 4.7 0.5 0.6 5.4 8.5 0.3 1.3 1.3 1.2 1.8 2.5 1.6 3.9 2.0 2.9 3.9 2.8 2.1 2.4 4.2 2.9 4.8 3.2 3.1 5.6 2.8 9.6 64.2 11.1 6.4 1.7 3.9 0.9 1.8 2.0 17.5 6.7 1.9 133.0 10.4 14.7 0.0 1.5 1.7 60.8 7.9 7.5 7.7 2.5 1.8 2.7 6.7 4.8 8.2 5.9 1.1 2.9 24.5 6.1 5.7 9.8 5.0 265.4 4.0 3.3 6.4 34.4 4.1 10.0 2.3 4.5 2.8 4.6 28.4 10.3 5.3 0.2 4.1 10.1 17.5 7.0 29.0 1.5 0.4 5.6 108.8 69.2 18.1 1.3 0.0 2.2 1.0 5.9 0.9 1.3 1.6 1.4 2.6 6.6 20.7 6.4 FNDC1 "bA243O10.1, dJ322A24.1, FNDC2, KIAA1866" ENSG00000164694 "Fibronectin type III domain containing 1" Q4ZHG4 6 159169400-159272108 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 14.2;thyroid gland: 20.3" "Group enriched" "Detected in some" 4 "Fibroblasts: 28.7;Smooth muscle cells: 11.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.5" "Group enriched" "Detected in many" 6 "cerebral cortex: 5.4;hippocampal formation: 8.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.0;fHDF/TERT166: 2.9;SuSa: 3.1" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA030962, HPA030963" Approved Approved "Nuclear speckles" "Secreted to extracellular matrix" NA NA 14000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA030962: AB_10696212, HPA030963: AB_2673676" "unprognostic (4.59e-2)" "unprognostic (9.17e-3)" "unprognostic (7.62e-2)" "prognostic favorable (6.10e-5)" "unprognostic (4.57e-1)" "unprognostic (2.11e-1)" "unprognostic (5.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "unprognostic (4.18e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.93e-6)" "unprognostic (6.49e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.76e-3)" 5.4 0.5 0.5 1.9 0.3 0.0 2.1 0.1 5.4 6.5 0.2 12.9 2.5 2.2 0.0 1.1 0.6 14.2 3.9 8.7 0.3 0.6 0.7 1.6 2.8 0.1 1.0 1.2 1.1 0.3 0.2 0.9 0.0 0.4 1.8 0.1 0.9 0.8 2.1 0.9 4.2 11.7 0.3 0.5 0.4 0.4 0.4 0.1 20.3 9.6 2.4 1.0 1.6 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 5.4 8.7 0.3 0.1 1.0 0.0 0.3 0.4 1.2 2.6 0.0 0.6 0.0 0.0 3.2 0.0 0.0 0.0 0.3 0.1 0.5 2.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.3 0.4 4.7 0.7 0.0 0.0 0.2 0.0 0.2 28.7 0.0 0.3 0.0 0.1 1.4 0.0 0.2 0.0 1.7 0.0 0.0 0.0 3.1 0.0 0.3 0.2 1.8 2.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 3.0 11.5 1.1 1.4 0.0 1.4 0.1 0.5 0.1 0.0 0.0 FNDC3B "DKFZp762K137, FAD104, FLJ23399, PRO4979, YVTM2421" ENSG00000075420 "Fibronectin type III domain containing 3B" Q53EP0 3 172039578-172401669 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 283.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "cerebral cortex: 29.4;hypothalamus: 8.2;pons: 9.4;thalamus: 14.4" "Immune cell enhanced" "Detected in many" "neutrophil: 37.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 37.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007859 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA007859: AB_1078900" "unprognostic (7.18e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (6.03e-2)" "unprognostic (6.38e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (3.25e-2)" "prognostic unfavorable (9.85e-4)" "unprognostic (2.17e-3)" "unprognostic (1.98e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (9.06e-5)" "unprognostic (3.50e-2)" "prognostic unfavorable (5.65e-7)" "unprognostic (4.35e-2)" "unprognostic (1.19e-1)" "unprognostic (3.51e-2)" "unprognostic (3.00e-2)" 34.4 25.5 1.1 26.3 1.1 37.0 16.6 0.6 29.4 26.0 11.9 19.8 13.0 21.9 18.2 9.2 12.5 19.4 24.4 3.5 8.2 17.5 28.5 21.8 8.9 3.3 3.4 22.8 28.3 15.0 8.5 52.7 9.4 12.9 19.6 4.4 21.3 15.6 21.2 7.0 11.4 25.4 0.7 14.7 20.6 9.3 14.4 6.8 32.4 18.5 11.0 38.6 9.5 1.9 47.4 55.9 36.0 43.5 107.6 73.6 87.6 68.3 73.1 43.3 58.3 30.5 100.5 4.2 178.9 99.0 85.6 27.4 12.4 53.2 74.9 27.5 9.2 6.0 34.8 78.6 109.2 62.1 100.1 75.5 24.9 80.8 75.9 102.8 116.7 8.1 10.9 32.6 44.3 14.8 2.4 24.9 20.8 18.0 22.0 5.4 37.5 21.9 44.8 42.1 2.2 10.8 62.2 30.6 53.9 49.3 31.1 28.5 182.6 60.5 28.5 78.9 52.2 67.3 84.0 9.3 63.5 32.7 61.0 13.5 8.3 20.4 4.2 5.3 1.8 1.1 1.3 2.3 4.7 0.1 1.4 2.5 37.5 4.6 2.7 0.7 1.2 3.4 1.1 1.1 0.6 29.4 3.5 8.2 3.3 3.4 9.4 0.7 14.4 1.9 54.8 86.6 49.0 115.2 19.2 63.9 51.4 61.1 39.3 7.5 27.4 31.9 51.0 41.5 47.9 46.0 12.5 41.4 29.2 53.1 15.6 69.8 16.2 73.7 73.4 61.5 16.8 16.4 37.9 45.6 99.6 103.7 32.6 179.5 15.2 95.2 58.2 68.9 47.1 0.0 43.9 30.7 12.2 59.2 53.3 9.3 57.5 65.1 69.4 155.5 52.2 17.4 39.1 115.6 31.4 78.5 44.8 54.5 283.6 67.8 16.1 35.7 33.6 11.5 52.6 89.4 69.1 2.3 3.2 18.6 33.5 34.8 23.1 26.0 26.2 88.4 FNTB FPTB ENSG00000257365 "Farnesyltransferase, CAAX box, beta" P49356 14 64986895-65062652 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA062743 Uncertain Approved Centrosome NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Centrosome "HPA062743: AB_2684861" "unprognostic (2.79e-1)" "unprognostic (1.50e-2)" "unprognostic (1.54e-1)" "unprognostic (8.57e-3)" "unprognostic (1.88e-1)" "unprognostic (6.88e-2)" "prognostic unfavorable (6.03e-4)" "unprognostic (6.21e-2)" "unprognostic (3.11e-2)" "unprognostic (1.46e-2)" "unprognostic (1.70e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-3)" "unprognostic (2.36e-2)" "unprognostic (3.60e-1)" "unprognostic (5.56e-2)" "unprognostic (1.11e-3)" 8.7 8.7 15.9 5.1 30.2 2.9 7.8 40.7 20.1 7.7 13.5 6.5 5.9 6.6 8.4 13.3 9.5 5.9 12.9 14.5 20.7 8.2 5.8 6.7 5.7 55.0 34.2 7.3 5.6 13.0 7.0 8.7 46.5 9.1 7.7 6.1 9.2 9.3 18.1 11.8 5.2 11.6 36.7 4.7 5.5 9.5 30.7 6.5 5.8 19.7 8.3 7.6 8.9 70.0 37.1 31.9 20.4 12.5 13.9 11.9 14.6 20.2 14.7 22.4 23.0 15.9 14.6 6.0 12.0 21.1 13.2 24.1 47.5 15.1 18.3 9.0 15.9 23.2 8.0 28.1 9.0 8.3 32.2 9.7 14.3 9.4 5.7 22.4 19.1 10.9 13.7 8.4 13.1 30.9 13.3 22.6 8.4 23.1 29.9 12.2 17.6 7.6 16.2 15.7 12.0 13.5 11.9 24.4 30.2 15.9 22.7 14.0 15.2 16.2 34.7 8.4 14.2 5.7 5.6 6.6 18.3 10.3 39.4 21.9 12.8 11.5 3.8 9.9 9.6 2.5 6.2 5.1 7.4 1.7 4.7 3.7 3.4 4.0 5.1 5.8 6.2 7.4 15.9 30.2 40.7 20.1 14.5 20.7 55.0 34.2 46.5 36.7 30.7 70.0 3.9 12.8 2.2 0.0 1.6 2.4 3.5 4.3 2.8 4.6 6.2 6.6 8.3 2.8 5.6 3.7 2.1 15.9 2.4 4.3 0.0 6.6 9.2 3.9 3.0 4.5 7.7 7.8 0.0 4.8 15.3 4.9 4.1 4.8 0.0 12.7 5.0 8.0 8.1 5.0 0.0 5.9 6.1 8.1 2.5 6.0 5.6 15.7 5.4 0.0 7.5 7.6 2.1 0.0 0.0 4.2 1.9 8.6 2.1 4.7 4.0 6.0 4.0 4.1 19.7 5.1 5.5 2.7 4.7 6.7 3.7 8.2 2.5 7.3 5.3 3.3 FOLR1 "FOLR, FRα" ENSG00000110195 "Folate receptor alpha" P15328 11 72189558-72196323 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" Transport Receptor Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 480.2;fallopian tube: 187.2;lung: 193.5;salivary gland: 219.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 496.8;Alveolar cells type 2: 213.3;Breast glandular cells: 211.3;Club cells: 276.3;Collecting duct cells: 318.2;Cytotrophoblasts: 462.2;Proximal tubular cells: 366.0;Syncytiotrophoblasts: 259.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 259.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HeLa: 444.2;RPTEC TERT1: 476.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077030 Approved "Nuclear membrane" "Secreted to blood" NA NA 448000 140000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear membrane" "HPA077030: " "unprognostic (3.30e-1)" "unprognostic (2.19e-1)" "unprognostic (6.55e-2)" "unprognostic (3.49e-2)" "unprognostic (7.67e-3)" "unprognostic (1.98e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.18e-2)" "unprognostic (8.13e-2)" "unprognostic (2.47e-2)" "unprognostic (2.58e-2)" "unprognostic (2.87e-3)" "unprognostic (1.67e-1)" "unprognostic (2.52e-1)" "unprognostic (1.11e-1)" "unprognostic (2.20e-1)" "unprognostic (2.69e-1)" 0.1 1.7 2.7 0.2 1.8 0.1 28.3 11.8 1.8 123.5 480.2 0.5 0.3 1.9 7.6 3.4 187.2 2.4 0.6 14.1 4.1 153.0 0.2 193.5 0.0 5.7 7.8 0.7 7.1 17.5 8.1 36.2 3.8 1.5 0.4 0.5 219.5 15.2 0.1 2.5 0.4 0.2 3.2 0.2 33.0 0.2 7.7 0.2 45.9 0.0 0.4 0.1 0.1 2.7 0.2 0.2 0.0 0.2 0.0 0.0 64.7 0.1 0.1 0.1 0.1 44.5 46.0 0.0 45.5 0.8 0.0 0.9 2.4 2.1 0.2 0.1 1.4 1.0 444.2 1.3 0.0 0.0 0.1 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.5 0.1 0.1 2.2 0.7 0.0 0.5 15.1 0.0 476.5 0.0 0.1 3.0 1.4 7.1 0.1 38.5 65.7 0.5 0.0 0.0 8.4 0.3 0.0 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 1.8 11.8 1.8 14.1 4.1 5.7 7.8 3.8 3.2 7.7 2.7 1.0 496.8 213.3 0.0 1.3 0.9 7.9 80.3 0.0 0.0 211.3 62.9 0.2 34.3 276.3 318.2 0.0 462.2 1.1 0.0 133.1 14.3 0.1 33.6 2.3 3.4 1.8 0.0 0.0 1.4 110.9 4.3 9.7 33.7 5.1 0.0 0.0 0.0 29.5 0.0 0.0 0.1 87.5 0.0 0.4 0.0 0.6 3.8 0.0 0.0 0.0 2.2 0.0 0.0 0.0 6.7 0.0 0.0 0.0 6.3 0.0 366.0 149.1 0.1 0.0 0.1 6.3 0.0 0.5 3.2 0.1 259.0 2.2 0.3 0.3 10.4 FOXA1 HNF3A ENSG00000129514 "Forkhead box A1" P55317 14 37589552-37596059 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 74.7;stomach 1: 28.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 113.8;Basal squamous epithelial cells: 76.8;Breast glandular cells: 87.9;Enteroendocrine cells: 84.6;Prostatic glandular cells: 89.8;Respiratory ciliated cells: 66.7;Urothelial cells: 154.5" "Group enriched" "Detected in many" 5 "breast cancer: 80.0;prostate cancer: 127.0" "Region enriched" "Detected in single" 5 "midbrain: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 48.9;MCF7: 105.3;PC-3: 69.5;RT4: 96.7;SK-BR-3: 97.0;T-47d: 135.9" "Region enhanced" "Detected in some" "midbrain: 1.1" "Region enriched" "Detected in single" 6 "midbrain: 5.4" "CAB011595, HPA050505" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nucleoli fibrillar center" "CAB011595: AB_2104842, HPA050505: AB_2681148" "unprognostic (1.61e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.65e-1)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (1.71e-1)" "unprognostic (3.01e-1)" "unprognostic (1.54e-2)" "unprognostic (6.30e-2)" "unprognostic (0.00e+0)" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.69e-2)" "prognostic favorable (1.00e-4)" 0.2 0.1 0.0 1.6 0.0 0.0 22.3 0.0 0.0 1.5 0.0 12.4 8.4 0.1 0.6 11.9 2.4 2.3 0.0 0.0 0.3 0.1 26.9 7.5 0.0 0.1 3.5 0.0 0.5 0.0 0.7 0.0 0.2 74.7 10.4 0.0 19.3 0.3 0.0 1.3 4.8 0.2 0.2 0.0 28.0 0.4 0.7 0.0 0.0 0.0 2.3 20.5 4.4 0.0 4.9 4.4 0.0 2.8 0.0 0.0 0.5 0.0 0.4 0.0 0.0 21.3 2.7 0.0 1.4 0.0 0.1 23.4 13.2 3.3 0.1 0.0 23.4 0.0 4.1 48.9 0.0 0.0 0.2 0.0 0.7 0.0 0.4 1.9 0.0 0.4 0.9 0.0 0.0 105.3 0.1 0.3 0.0 32.0 69.5 0.0 1.1 0.4 9.9 96.7 11.8 0.0 4.8 97.0 0.0 0.0 135.9 0.4 0.0 0.9 0.1 0.4 3.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 3.5 0.2 0.2 0.7 0.0 0.3 28.9 43.5 0.0 0.1 1.0 113.8 47.8 76.8 0.0 87.9 34.8 1.3 30.0 52.3 3.7 0.0 0.0 0.5 27.5 0.0 1.5 0.4 2.7 0.2 1.2 84.6 0.0 0.0 2.4 0.0 1.0 35.7 4.4 2.5 0.0 1.1 31.7 0.0 0.0 0.0 34.9 42.7 0.9 0.3 0.9 0.0 0.7 3.6 0.0 1.0 0.0 0.0 0.0 0.0 4.3 27.2 0.0 1.2 89.8 4.9 0.0 66.7 0.0 0.0 0.0 2.3 0.9 1.2 62.9 0.1 0.0 1.4 0.1 27.9 154.5 FOXF2 "FKHL6, FREAC2" ENSG00000137273 "Forkhead box F2" Q12947 6 1389576-1395603 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.2" "Cell type enhanced" "Detected in some" "Endothelial cells: 5.2;Fibroblasts: 7.9;Microglial cells: 19.7;Smooth muscle cells: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 70.4;HEK 293: 24.3;U-2197: 28.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.14e-2)" "unprognostic (2.03e-1)" "unprognostic (8.33e-2)" "unprognostic (1.68e-1)" "unprognostic (5.39e-2)" "unprognostic (3.32e-2)" "unprognostic (8.12e-2)" "unprognostic (1.11e-1)" "unprognostic (9.89e-3)" "unprognostic (2.53e-1)" "unprognostic (4.50e-2)" "unprognostic (8.76e-2)" "unprognostic (8.75e-7)" "unprognostic (1.03e-1)" "unprognostic (4.74e-2)" "unprognostic (2.08e-2)" "unprognostic (8.29e-2)" 1.8 0.4 8.1 1.8 6.0 0.0 2.4 5.5 10.3 1.0 5.1 40.2 6.0 0.2 0.8 9.6 0.5 1.5 0.7 6.1 5.2 0.2 0.1 17.8 0.4 10.1 6.0 0.1 1.0 0.6 7.6 9.1 10.0 10.8 9.3 0.1 1.3 0.6 1.0 1.4 18.7 3.5 5.1 0.0 17.8 0.9 7.1 0.0 3.7 3.5 1.8 11.1 2.1 6.9 1.6 3.4 1.0 0.8 3.2 4.9 0.1 15.6 70.4 6.3 2.9 0.3 0.0 0.0 3.3 4.6 6.8 11.9 12.2 0.6 2.8 0.0 24.3 0.0 5.7 0.0 6.1 0.0 0.4 0.8 5.0 0.0 5.9 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.1 0.1 0.0 0.0 0.0 6.9 0.2 0.0 3.7 0.0 5.2 1.3 0.0 0.2 0.0 5.8 11.0 28.7 2.8 0.3 0.0 0.0 0.0 4.7 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 6.0 5.5 10.3 6.1 5.2 10.1 6.0 10.0 5.1 7.1 6.9 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.0 5.2 0.0 0.0 1.1 0.0 1.5 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.4 2.5 0.1 1.8 19.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 5.5 0.2 1.5 0.3 0.1 0.1 0.1 0.0 0.0 0.0 FOXI1 "FKHL10, FREAC6" ENSG00000168269 "Forkhead box I1" Q12951 5 170105897-170109734 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 44.0;salivary gland: 11.4" "Cell type enriched" "Detected in some" 4 "Ionocytes: 132.2" "Group enriched" "Detected in many" 7 "breast cancer: 5.8;renal cancer: 23.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.5" "Group enriched" "Detected in some" 5 "MCF7: 1.4;SuSa: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA071469 Enhanced Supported Nucleoli,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Vesicles "HPA071469: AB_2686403" "unprognostic (3.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.09e-1)" "unprognostic (2.48e-2)" "unprognostic (8.06e-2)" "unprognostic (7.47e-2)" "unprognostic (2.73e-1)" "unprognostic (1.52e-2)" "unprognostic (9.71e-3)" "unprognostic (4.88e-3)" "unprognostic (6.20e-2)" "unprognostic (1.34e-2)" "unprognostic (2.22e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 44.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.5 0.1 0.0 0.1 3.0 0.0 0.0 11.4 1.5 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.5 0.2 0.0 0.0 7.6 6.5 0.3 0.0 0.3 1.8 0.0 0.0 0.1 0.0 27.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 132.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 FOXJ1 "FKHL13, HFH-4, HFH4" ENSG00000129654 "Forkhead box J1" Q92949 17 76136333-76141245 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 43.4;choroid plexus: 80.1;fallopian tube: 53.2" "Group enriched" "Detected in many" 8 "Endometrial ciliated cells: 234.7;Respiratory ciliated cells: 124.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 73.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "BEWO: 29.9;CAPAN-2: 25.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "midbrain: 43.1" HPA005714 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA005714: AB_1078902" "prognostic favorable (9.39e-4)" "unprognostic (4.97e-3)" "unprognostic (1.22e-1)" "unprognostic (2.77e-3)" "unprognostic (1.19e-1)" "unprognostic (2.54e-3)" "unprognostic (1.71e-3)" "unprognostic (6.15e-2)" "unprognostic (1.00e-2)" "unprognostic (7.84e-3)" "unprognostic (1.43e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.03e-5)" "unprognostic (7.49e-2)" "unprognostic (1.94e-1)" "unprognostic (2.27e-1)" "unprognostic (1.91e-1)" 0.0 0.0 12.2 0.1 12.7 0.3 0.0 13.0 10.8 6.6 80.1 0.6 0.3 2.2 0.5 0.3 53.2 0.0 0.0 14.6 18.3 3.4 0.0 10.4 0.0 36.7 43.4 0.2 0.9 0.0 2.2 0.0 25.2 0.5 0.2 0.4 0.1 2.5 0.4 0.8 0.2 0.0 23.3 0.0 0.5 16.7 22.6 0.2 3.0 0.0 0.0 0.9 0.1 14.9 0.0 0.5 1.7 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 3.1 25.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 12.2 12.7 13.0 10.8 14.6 18.3 36.7 43.4 25.2 23.3 22.6 14.9 2.2 9.6 3.1 1.0 2.3 0.8 1.0 4.4 0.0 0.4 5.6 4.2 0.9 1.5 12.0 9.2 4.2 0.2 4.8 1.0 0.0 0.6 21.4 234.7 4.5 0.7 1.8 3.0 0.0 0.0 0.6 1.6 4.1 10.7 1.3 0.1 0.4 0.0 0.1 0.0 0.1 3.2 4.1 0.6 0.0 19.1 0.3 1.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.2 0.8 0.4 1.3 0.5 0.2 3.5 124.0 8.7 0.0 1.8 3.5 20.7 2.0 0.8 0.9 0.3 3.5 1.1 2.3 0.7 FOXJ2 FHX ENSG00000065970 "Forkhead box J2" Q9P0K8 12 8032716-8055517 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008723 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nucleoli fibrillar center" "HPA008723: AB_1078903" "unprognostic (1.68e-1)" "unprognostic (2.70e-1)" "unprognostic (1.22e-2)" "unprognostic (1.11e-1)" "unprognostic (1.37e-2)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (9.65e-2)" "unprognostic (3.08e-1)" "unprognostic (2.74e-3)" "unprognostic (3.40e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.63e-4)" "unprognostic (9.01e-2)" "unprognostic (2.48e-2)" "unprognostic (2.30e-2)" "unprognostic (2.02e-2)" 13.8 8.3 6.6 8.7 6.7 15.5 12.3 14.3 11.9 15.5 4.6 14.8 7.3 17.7 8.0 8.8 14.4 8.1 14.7 6.7 6.6 7.3 5.9 12.1 8.3 6.3 6.2 16.8 10.0 15.4 8.5 11.0 6.1 10.6 7.7 9.3 9.5 12.8 25.2 17.5 10.1 14.7 5.1 10.8 11.3 5.8 6.2 10.7 9.9 20.6 9.1 13.5 12.3 7.0 12.4 10.3 11.1 14.0 12.6 13.8 24.3 17.5 17.8 16.7 12.4 14.8 13.3 0.2 3.2 21.3 15.4 13.2 10.0 11.7 17.8 21.6 6.8 16.4 11.8 5.1 15.8 7.4 43.9 12.2 17.2 21.7 31.5 17.4 12.1 13.0 12.2 8.0 13.7 9.6 10.5 6.6 12.6 18.4 6.8 11.2 17.2 6.0 7.0 8.2 4.6 6.3 22.0 15.1 7.6 23.1 3.5 8.8 11.0 20.3 24.8 14.5 10.7 6.4 6.8 8.1 13.1 5.9 12.3 2.5 1.4 2.2 1.5 1.1 1.9 0.8 1.5 1.7 1.8 1.5 1.7 1.5 2.7 2.8 1.5 1.7 1.2 1.2 6.6 6.7 14.3 11.9 6.7 6.6 6.3 6.2 6.1 5.1 6.2 7.0 14.1 16.0 13.1 6.2 9.1 18.9 4.5 5.5 14.8 10.7 10.4 9.1 19.9 12.8 4.0 0.0 8.4 5.5 7.7 7.1 0.0 5.9 0.4 4.0 14.0 12.8 4.9 13.7 6.1 7.5 3.1 12.0 7.7 7.2 3.8 16.1 18.9 9.5 10.1 8.4 6.4 8.4 4.1 13.2 23.0 0.9 10.5 13.9 7.2 6.5 14.2 4.0 11.3 3.0 5.7 10.3 4.4 17.0 6.7 9.8 5.0 2.4 2.9 7.5 19.7 9.9 8.4 1.4 6.4 14.2 21.5 6.2 12.3 8.1 7.4 5.3 FOXK2 "ILF, ILF1" ENSG00000141568 "Forkhead box K2" Q01167 17 82519713-82644662 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027523, HPA073491" Approved Supported Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Mitochondria" "HPA027523: AB_10601013, HPA073491: " "unprognostic (2.39e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (9.52e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (3.35e-2)" "unprognostic (2.25e-1)" "unprognostic (5.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "unprognostic (3.80e-3)" "unprognostic (2.24e-2)" "unprognostic (4.89e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" 14.0 24.0 10.7 12.6 13.2 8.0 12.1 14.7 16.3 14.2 1.2 18.1 9.3 19.7 9.8 20.2 13.2 10.0 17.1 12.4 10.5 12.7 13.1 14.2 12.5 5.8 7.1 14.7 15.4 20.0 17.7 15.7 6.3 13.3 9.4 11.6 12.1 12.5 43.0 18.8 12.1 16.4 3.0 11.6 14.7 28.1 9.4 18.4 15.4 28.4 11.9 15.5 13.4 12.7 48.4 50.4 46.3 50.9 26.2 28.5 31.0 27.6 31.6 47.4 47.9 49.1 30.1 40.7 19.6 34.4 52.3 27.6 49.7 32.0 44.4 28.3 47.9 42.3 32.7 49.4 41.0 47.3 27.2 27.2 57.2 50.4 56.8 29.2 48.9 43.7 57.7 40.7 26.3 28.8 81.8 30.4 26.5 39.7 38.2 53.0 39.4 34.2 21.7 40.1 76.2 56.1 27.4 69.0 65.1 48.8 48.7 54.3 38.3 62.2 43.2 42.2 56.6 46.7 45.1 53.5 33.4 39.0 33.4 1.5 1.0 1.2 1.4 0.7 1.1 1.5 1.1 1.4 1.2 1.0 0.8 0.9 0.1 1.6 0.9 2.0 1.3 0.6 10.7 13.2 14.7 16.3 12.4 10.5 5.8 7.1 6.3 3.0 9.4 12.7 21.5 51.3 27.1 23.5 11.5 37.2 8.0 10.6 10.2 19.2 17.7 15.7 19.5 7.2 16.2 14.7 12.5 11.9 19.3 15.6 3.9 8.7 15.6 19.4 22.4 14.9 10.9 7.8 44.6 10.7 8.8 13.2 14.3 26.7 2.5 22.1 10.8 13.4 20.0 47.1 39.6 12.6 8.2 17.3 22.0 24.1 9.3 19.2 12.4 20.6 13.9 12.3 6.2 33.2 49.1 11.4 12.4 13.2 13.3 13.6 12.2 7.1 13.9 16.7 0.0 19.8 16.6 15.0 10.3 17.0 43.0 9.7 11.6 30.6 13.0 10.7 FOXM1 "FKHL16, HFH-11, HNF-3, INS-1, MPHOSPH2, MPP2, TGT3, trident" ENSG00000111206 "Forkhead box M1" Q08050 12 2857680-2877174 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.0;lymphoid tissue: 32.2;testis: 21.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.4;Erythroid cells: 18.7;Extravillous trophoblasts: 18.2;Late spermatids: 25.5;Plasma cells: 19.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" CAB017832 Uncertain Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Cytosol "CAB017832: " "unprognostic (3.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (4.30e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.95e-6)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.01e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (6.09e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (1.94e-1)" 1.9 1.1 0.4 9.4 0.5 25.0 1.8 0.8 0.8 1.7 0.2 10.5 9.7 1.7 0.2 11.1 0.8 1.5 0.5 0.8 0.3 0.7 1.2 1.8 11.3 0.4 0.9 0.3 0.4 0.4 0.1 6.1 0.6 0.7 12.5 1.1 1.9 0.8 0.6 6.4 8.8 7.5 0.1 3.1 5.2 21.4 1.0 32.2 0.9 0.3 15.2 3.0 3.2 0.6 133.0 129.5 101.3 92.2 14.2 19.0 129.2 84.0 80.4 165.2 147.2 166.9 114.8 84.5 17.7 119.8 188.5 100.2 153.1 76.1 160.0 159.8 80.3 94.7 121.6 71.6 2.0 79.2 75.0 9.9 8.3 154.4 106.1 39.1 117.8 96.8 55.6 184.9 130.5 122.6 108.3 36.8 225.6 136.1 95.4 77.3 149.8 44.1 38.1 82.7 56.3 89.1 106.7 90.4 46.6 189.4 87.1 87.8 48.0 134.3 200.5 160.4 300.4 24.7 44.3 122.1 63.1 74.3 147.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.5 0.8 0.8 0.8 0.3 0.4 0.9 0.6 0.1 1.0 0.6 0.1 0.0 1.3 0.7 2.4 2.9 1.3 1.0 1.2 2.0 1.7 1.3 0.5 1.5 0.8 1.8 4.2 7.1 0.8 6.6 1.9 0.2 22.4 1.2 2.1 2.5 0.0 18.7 1.1 0.0 18.2 3.2 10.2 2.4 0.0 15.4 3.6 0.8 9.1 5.0 0.6 7.5 2.0 4.2 1.2 25.5 0.9 2.4 0.0 0.0 1.1 0.6 1.0 0.5 1.0 0.3 0.3 0.7 19.9 1.0 1.4 0.4 0.2 4.0 0.0 1.2 3.0 15.0 9.9 10.2 1.4 1.9 3.3 0.9 12.9 1.9 FOXP1 "12CC4, hFKH1B, HSPC215, QRF1" ENSG00000114861 "Forkhead box P1" Q9H334 3 70954708-71583989 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 41.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTEC/SVTERT24-B: 95.0" "Low region specificity" "Detected in all" "HPA003876, CAB011501" Supported Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB011501: AB_732428, HPA003876: AB_1078907" "unprognostic (2.31e-1)" "unprognostic (4.35e-3)" "unprognostic (2.09e-2)" "unprognostic (3.54e-2)" "unprognostic (2.69e-1)" "unprognostic (2.81e-3)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (2.03e-1)" "unprognostic (4.38e-3)" "unprognostic (3.40e-1)" "unprognostic (6.14e-2)" "unprognostic (1.05e-1)" "unprognostic (8.65e-2)" "unprognostic (1.27e-1)" "unprognostic (6.05e-2)" 16.5 3.8 5.0 20.3 41.1 38.5 14.5 0.3 12.5 11.2 9.9 28.7 12.2 15.3 6.5 23.0 14.3 21.0 12.7 7.8 0.0 7.0 13.0 22.9 22.2 3.1 6.7 32.4 16.8 6.5 9.1 13.7 0.9 21.2 23.4 2.6 29.7 9.6 8.2 10.9 15.3 22.7 0.1 17.8 20.6 14.4 6.6 26.3 14.5 11.1 25.4 21.6 14.2 8.1 9.6 8.0 16.8 13.2 8.4 21.3 8.2 26.3 30.9 22.0 17.4 51.9 11.2 31.1 4.3 12.9 17.6 6.9 31.0 22.8 40.3 7.8 11.7 13.0 17.0 52.7 20.5 25.7 31.6 21.7 10.3 95.0 42.1 18.3 36.6 15.4 13.6 36.7 10.8 42.6 11.9 9.3 19.7 7.2 39.9 38.0 30.7 4.7 18.8 30.1 14.5 27.6 32.6 7.7 1.9 15.9 5.6 21.9 47.7 34.9 14.3 48.9 42.2 9.0 7.1 41.8 22.5 35.7 7.5 46.9 15.3 15.2 18.3 13.1 19.4 58.1 38.7 22.6 13.0 62.2 60.8 40.0 27.0 22.2 25.3 21.7 35.9 28.8 5.0 41.1 0.3 12.5 7.8 0.0 3.1 6.7 0.9 0.1 6.6 8.1 158.8 73.7 121.3 130.9 266.5 183.0 170.6 58.2 176.4 30.3 98.5 115.1 42.1 148.7 72.0 33.1 18.8 47.2 122.9 118.1 31.3 79.0 156.0 116.3 48.2 184.9 271.6 111.5 391.0 95.1 12.6 90.4 95.8 128.0 219.8 117.7 184.9 72.3 49.5 6.7 139.9 231.2 154.6 117.6 209.0 89.6 42.0 101.3 37.4 414.1 120.3 15.5 116.4 184.5 286.4 124.8 102.8 24.8 66.0 178.8 91.7 19.4 83.7 42.8 92.1 102.9 119.4 13.7 33.6 111.5 101.4 52.4 168.1 33.1 157.2 146.3 FOXP2 "CAGH44, SPCH1, TNRC10" ENSG00000128573 "Forkhead box P2" O15409 7 114086327-114693772 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.8" "Group enriched" "Detected in many" 4 "Excitatory neurons: 186.8;Microglial cells: 288.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 21.0;RH-30: 37.3;THP-1: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000382, HPA000383, HPA001679" Enhanced Enhanced Nucleoplasm NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA000382: AB_1078908, HPA000383: AB_1078909, HPA001679: AB_2666415" "unprognostic (1.21e-1)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (8.83e-3)" "unprognostic (4.66e-1)" "unprognostic (3.69e-4)" "unprognostic (2.04e-2)" "unprognostic (6.22e-2)" "unprognostic (2.17e-1)" "unprognostic (6.70e-3)" "unprognostic (1.22e-1)" "unprognostic (1.77e-1)" "unprognostic (8.04e-2)" "unprognostic (4.16e-3)" "unprognostic (2.84e-1)" "unprognostic (9.81e-2)" "unprognostic (4.19e-2)" 1.9 1.3 1.8 1.9 1.3 0.4 2.0 0.0 10.1 5.0 0.0 18.8 2.5 8.0 1.7 6.1 3.4 3.5 1.4 2.7 0.9 2.0 2.5 1.5 1.0 1.5 6.9 9.7 4.6 0.6 0.9 0.5 1.9 2.2 5.2 3.2 2.8 1.4 3.2 3.7 3.2 7.7 0.0 0.5 4.2 1.3 2.6 0.2 4.9 1.8 0.7 6.1 4.3 5.2 0.4 3.2 21.0 0.0 4.9 6.2 1.3 3.5 3.6 0.7 0.4 1.6 0.3 0.3 0.8 1.2 0.1 0.5 0.8 0.0 0.1 0.2 7.0 8.0 4.6 6.6 0.0 0.5 0.5 1.3 0.8 0.1 0.0 1.3 0.0 0.0 1.8 3.0 0.8 1.5 1.8 1.2 1.1 0.4 1.0 0.6 37.3 7.9 0.5 8.6 5.1 2.2 0.0 1.3 1.1 1.2 1.0 11.9 1.6 1.3 0.6 2.0 0.7 6.3 0.7 1.0 1.5 0.8 0.6 9.7 5.5 11.4 5.9 7.4 5.8 10.1 6.4 6.3 6.7 8.2 6.5 7.4 5.5 6.6 6.3 16.6 10.7 20.5 1.8 1.3 0.0 10.1 2.7 0.9 1.5 6.9 1.9 0.0 2.6 5.2 0.5 0.0 8.2 5.5 0.0 30.7 2.9 5.5 48.3 0.1 1.8 1.3 1.6 10.0 7.3 3.7 2.1 0.1 0.0 4.8 0.0 0.1 9.7 0.1 1.2 1.9 4.2 0.0 186.8 5.4 0.0 20.6 1.1 0.0 0.0 16.2 8.2 11.7 0.2 13.5 6.4 11.5 2.0 1.6 5.6 6.2 5.3 0.4 3.6 288.6 0.0 27.7 0.0 5.5 4.6 1.3 18.5 0.7 0.6 2.3 8.6 3.8 11.3 1.3 0.0 25.5 1.7 2.4 1.4 25.3 25.6 0.3 0.3 4.2 11.5 4.0 FOXQ1 HFH1 ENSG00000164379 "Forkhead box Q1" Q9C009 6 1312098-1314758 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 107.2;urinary bladder: 53.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.4;Basal respiratory cells: 24.9;Collecting duct cells: 40.5;Gastric mucus-secreting cells: 67.2;Suprabasal keratinocytes: 45.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 39.0;HaCaT: 44.7;Hep G2: 93.8;OE19: 117.1;RT4: 38.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059700 Supported Nucleoplasm Yes NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA059700: AB_2684107" "unprognostic (2.04e-3)" "unprognostic (3.44e-1)" "unprognostic (1.10e-1)" "unprognostic (7.18e-2)" "unprognostic (1.50e-3)" "unprognostic (2.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.68e-4)" "unprognostic (1.49e-2)" "unprognostic (3.16e-3)" "unprognostic (2.82e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" 0.3 0.0 6.9 0.2 5.2 0.0 1.4 7.1 7.1 6.7 3.8 0.8 10.4 0.9 0.3 11.3 3.9 5.4 0.0 4.7 5.1 9.8 6.4 4.0 0.0 5.6 6.0 0.0 6.5 0.1 2.5 1.1 6.0 8.9 0.4 0.1 30.4 1.1 0.2 25.7 0.6 0.0 5.3 0.0 107.2 0.2 7.5 0.6 3.6 0.6 8.0 53.5 16.9 4.7 16.0 1.4 0.0 0.0 0.0 0.0 0.0 0.7 13.5 0.1 0.1 39.0 22.6 0.0 0.7 0.0 0.1 44.7 0.0 1.7 0.0 0.0 1.1 0.0 8.2 93.8 0.0 0.0 2.4 0.0 16.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 117.1 0.8 0.0 0.0 0.0 0.4 38.2 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 5.2 7.1 7.1 4.7 5.1 5.6 6.0 6.0 5.3 7.5 4.7 0.3 16.0 10.6 0.0 0.0 60.4 3.2 24.9 6.8 0.0 5.3 5.1 0.8 0.0 16.8 40.5 0.0 0.0 0.0 0.0 1.9 3.0 0.0 5.2 3.0 0.4 0.0 0.0 1.2 13.4 0.0 1.4 67.2 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 2.9 0.0 0.0 0.7 1.8 15.9 0.0 0.0 0.0 0.0 0.5 11.8 0.0 0.0 0.2 0.6 0.0 6.2 5.0 0.0 0.0 0.0 1.6 0.0 0.0 22.2 45.5 0.0 0.3 0.0 0.0 3.9 FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 195.3;lymphoid tissue: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 119.6;Kupffer cells: 215.3;Macrophages: 178.5;monocytes: 89.7" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4199.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 4199.5" "Group enriched" "Detected in some" 5 "LHCN-M2: 17.2;U-87 MG: 67.1" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" 69.6 10.0 3.8 166.0 4.4 195.3 5.3 4.1 8.7 8.2 5.7 4.6 3.1 3.7 0.5 8.9 15.4 28.6 7.5 3.6 8.1 4.5 21.4 50.8 12.7 15.2 8.2 2.4 11.2 5.1 3.5 45.1 11.9 3.1 3.3 2.6 4.1 2.3 1.8 1.3 5.2 42.9 8.6 129.2 5.4 2.2 9.9 8.4 3.1 22.8 10.3 66.9 2.7 18.2 0.5 0.8 0.3 0.4 1.0 2.1 0.5 0.2 0.0 0.5 2.0 0.3 0.7 1.2 0.6 0.0 3.9 0.4 0.0 0.0 0.1 0.1 0.0 0.7 0.9 1.0 6.0 0.3 0.5 4.8 0.2 1.8 1.8 9.2 0.0 0.3 0.1 0.6 17.2 0.9 0.1 0.3 0.4 0.3 0.7 0.3 0.7 0.0 1.5 0.5 0.2 0.3 0.6 0.1 0.5 0.2 1.0 1.1 1.0 2.0 0.4 0.1 3.5 0.2 0.0 0.5 67.1 1.7 0.1 317.1 759.9 204.9 1.6 319.7 1.5 0.7 1.0 0.7 174.1 1.0 1.0 1.2 4199.5 0.4 201.8 8.1 1.3 420.3 3.8 4.4 4.1 8.7 3.6 8.1 15.2 8.2 11.9 8.6 9.9 18.2 0.1 16.0 25.7 0.0 1.8 0.6 0.3 0.0 0.0 1.0 0.1 0.3 0.2 0.0 15.5 0.0 0.0 1.1 0.3 0.0 0.0 0.0 1.8 0.0 0.1 6.3 0.0 2.5 0.2 0.0 1.6 4.7 0.5 0.1 26.5 0.0 2.5 2.1 119.6 0.0 0.1 0.0 0.0 215.3 4.7 2.0 0.3 178.5 0.0 3.7 89.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.4 8.8 0.3 6.6 0.6 0.8 0.6 0.8 0.2 0.0 3.0 2.5 0.0 0.0 0.1 FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 7 "Early spermatids: 73.7;Inhibitory neurons: 126.1;Late spermatids: 144.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HEL: 163.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" 5.3 2.5 0.9 0.8 1.1 0.2 4.8 4.2 1.3 5.0 2.0 6.4 2.1 19.7 36.4 1.0 4.1 3.7 6.4 1.1 1.3 17.0 0.9 2.4 0.0 2.0 1.3 1.4 6.6 5.0 1.0 5.5 1.2 1.1 1.7 1.3 0.8 3.4 0.9 3.3 5.4 14.2 3.0 0.4 1.0 4.2 1.2 1.2 0.7 0.8 0.5 2.1 2.3 3.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.8 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.4 3.7 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 4.2 1.3 1.1 1.3 2.0 1.3 1.2 3.0 1.2 3.8 0.4 0.0 0.6 13.1 0.3 1.3 0.2 0.0 0.6 2.0 0.1 0.1 2.9 2.8 0.0 1.8 0.0 0.5 0.0 0.2 0.0 0.3 73.7 1.5 7.7 0.4 0.0 3.0 16.2 0.0 0.3 11.2 0.5 1.3 5.1 0.2 3.9 0.0 0.5 0.0 126.1 2.4 0.0 0.6 1.2 144.7 0.6 0.1 0.0 6.5 0.6 4.0 0.0 7.1 4.3 0.2 0.0 1.5 0.0 0.1 13.0 1.3 0.0 0.1 0.0 0.6 2.8 0.8 0.9 0.0 1.1 0.3 0.1 6.1 4.7 0.1 FRMD1 "bA164L23.1, DKFZp434O0117, FLJ00181, FLJ22615, FLJ40260" ENSG00000153303 "FERM domain containing 1" Q8N878 6 168053166-168101511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;lymphoid tissue: 13.1;stomach 1: 5.7;testis: 5.1" "Group enriched" "Detected in some" 4 "Distal enterocytes: 68.9;Paneth cells: 167.2" "Cancer enriched" "Detected in single" 6 "colorectal cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 1.9;RPMI-8226: 3.0" "Low region specificity" "Detected in many" HPA030347 Enhanced Approved "Actin filaments" NA NA "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "HPA030347: AB_10600207" "unprognostic (2.43e-2)" "unprognostic (2.74e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.58e-4)" "unprognostic (8.63e-2)" "unprognostic (2.62e-1)" "unprognostic (7.51e-2)" "unprognostic (9.12e-2)" "unprognostic (8.23e-2)" "unprognostic (1.71e-2)" "unprognostic (1.01e-1)" "unprognostic (9.11e-3)" 3.6 0.0 0.0 0.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 6.8 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.2 0.0 3.1 0.1 0.0 2.1 5.7 5.1 0.0 13.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 1.8 0.0 0.0 0.0 68.9 0.0 0.0 15.3 0.0 0.0 0.2 7.8 0.0 0.0 1.8 0.0 0.4 4.6 0.1 0.0 0.3 0.4 0.6 0.0 0.0 0.0 16.0 0.0 0.0 0.0 20.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.2 1.5 0.0 0.0 19.6 23.8 0.0 0.0 0.0 0.3 0.7 13.4 8.2 0.0 0.0 0.1 0.1 15.2 12.6 0.2 FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.0;skeletal muscle: 81.2;tongue: 74.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.6;Cardiomyocytes: 73.7;Cone photoreceptor cells: 79.2;Early spermatids: 121.9;Horizontal cells: 101.0;Late spermatids: 122.8;Sertoli cells: 72.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Cell line enhanced" "Detected in many" "HEL: 24.0;OE19: 49.2;RPMI-8226: 79.6;SCLC-21H: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 38: Heart - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" 9.4 7.3 6.6 2.0 5.5 5.4 6.7 4.3 6.8 3.0 12.0 5.5 2.9 2.7 15.7 2.5 2.2 2.5 85.0 6.3 7.7 14.9 0.7 4.0 1.3 10.1 8.5 1.4 1.6 20.6 4.2 14.8 7.3 2.8 6.6 21.6 2.9 7.8 81.2 2.1 6.7 3.5 7.6 7.2 2.8 9.9 9.9 1.1 7.1 74.7 0.5 4.6 2.6 5.4 0.0 4.3 3.8 0.3 0.7 0.2 0.3 4.1 0.3 0.1 0.0 0.5 5.2 0.9 4.7 1.9 0.9 0.2 0.2 0.0 0.0 0.2 0.2 24.0 4.8 2.8 0.2 0.0 0.3 1.0 0.1 0.0 0.2 0.2 2.7 0.1 0.1 0.1 4.9 0.7 0.0 0.1 0.4 49.2 7.2 0.1 3.0 79.6 6.2 10.1 28.4 13.8 1.4 0.3 0.9 0.6 1.7 0.8 4.4 0.2 0.6 0.1 2.9 0.4 0.3 0.0 0.9 7.6 2.8 0.0 2.0 0.0 0.2 3.4 0.4 0.3 0.1 0.0 0.2 0.4 0.0 0.0 2.5 0.3 1.5 0.4 0.0 6.0 6.6 5.5 4.3 6.8 6.3 7.7 10.1 8.5 7.3 7.6 9.9 5.4 38.4 22.4 1.1 6.2 0.4 1.0 1.0 0.6 0.6 108.6 2.6 1.9 73.7 15.7 1.8 1.8 79.2 0.4 0.2 28.9 17.6 2.8 121.9 2.8 1.4 25.8 1.2 0.8 37.9 2.0 1.2 8.8 2.0 3.9 0.0 0.4 4.2 0.3 0.8 101.0 70.0 38.3 0.0 4.4 0.6 122.8 2.1 8.3 0.0 27.2 4.2 3.9 1.0 10.1 16.0 2.3 10.0 4.9 0.0 1.6 43.6 12.4 3.2 7.0 72.3 66.6 50.7 4.1 1.4 0.2 1.3 0.1 0.9 29.8 2.4 2.3 FRMD4A "bA295P9.4, FLJ10210, FRMD4, KIAA1294" ENSG00000151474 "FERM domain containing 4A" Q9P2Q2 10 13643706-14462142 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 60.8" "Group enriched" "Detected in many" 7 "Excitatory neurons: 1527.6;Inhibitory neurons: 1622.8;Microglial cells: 1329.4;Oligodendrocyte precursor cells: 442.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.3" "Lineage enriched" "Detected in single" 5 "B-cells: 2.3" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 134.0;HUVEC TERT2: 105.8;TIME: 191.6;WM-115: 163.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038449 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoplasm "HPA038449: AB_10669539" "unprognostic (6.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.51e-3)" "unprognostic (5.68e-2)" "unprognostic (1.55e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.21e-3)" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (9.20e-2)" "unprognostic (1.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" "unprognostic (8.16e-2)" "unprognostic (1.84e-1)" 60.8 5.2 38.9 11.7 28.1 5.4 18.7 0.0 29.2 8.6 0.0 13.1 5.7 5.7 4.0 9.4 8.8 9.6 16.7 24.1 8.5 19.5 12.2 14.2 9.1 15.6 10.9 6.8 15.5 2.4 8.7 22.5 6.2 10.3 6.4 14.1 13.6 10.2 8.1 32.0 7.4 6.5 10.0 32.8 7.9 8.8 14.4 15.6 8.1 7.3 8.4 10.4 8.9 18.9 7.0 7.1 90.1 0.5 12.3 22.0 16.9 40.8 36.5 35.2 48.7 12.1 4.2 0.1 28.3 21.5 48.6 13.5 0.3 3.3 30.7 0.3 9.9 1.4 0.9 0.2 11.0 0.5 1.1 12.8 3.2 134.0 16.4 98.9 105.8 3.1 13.6 0.4 64.7 8.5 4.6 0.8 24.6 0.3 9.6 0.4 30.8 0.2 16.6 5.8 4.3 15.9 0.2 32.7 64.4 16.1 18.5 3.3 191.6 48.8 17.4 47.6 49.3 0.3 0.4 0.3 41.7 1.0 163.4 0.1 0.1 0.0 0.0 0.1 0.1 0.8 0.3 0.1 0.0 2.3 0.3 0.0 0.3 0.2 0.0 0.4 0.4 0.0 38.9 28.1 0.0 29.2 24.1 8.5 15.6 10.9 6.2 10.0 14.4 18.9 48.6 32.1 2.6 168.1 1.7 35.1 13.1 3.0 9.1 54.2 17.1 14.4 11.4 45.8 4.1 33.1 18.8 69.6 0.4 1.1 11.7 15.8 42.5 13.1 5.5 44.0 4.8 81.7 1527.6 4.0 42.1 14.9 4.6 26.9 15.2 58.1 44.3 6.2 35.9 80.8 1622.8 3.4 6.1 95.6 19.9 98.8 2.1 25.5 16.0 1329.4 2.7 46.0 0.0 442.3 61.0 1.8 1.4 1.9 0.9 8.0 0.3 2.7 2.5 12.9 13.1 41.2 45.5 1.3 2.1 20.6 32.7 28.7 3.0 5.3 5.4 4.3 FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 336.9" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 3633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.2;ASC diff: 9.4;NTERA-2: 7.4;SH-SY5Y: 6.5" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 44000 "Cluster 19: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.64e-2)" "unprognostic (2.38e-2)" "unprognostic (4.67e-2)" "unprognostic (8.58e-2)" "unprognostic (5.41e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (3.53e-2)" "unprognostic (1.05e-2)" "unprognostic (6.04e-2)" "unprognostic (3.21e-1)" 10.4 5.7 10.4 6.1 12.8 0.7 12.6 11.0 18.6 20.3 52.2 16.2 14.4 17.2 11.4 12.4 7.1 39.0 19.9 10.3 11.2 16.3 3.3 9.1 18.7 14.1 10.9 13.5 7.1 6.7 18.6 30.5 15.4 12.9 19.9 336.9 4.7 16.6 26.6 10.4 14.5 31.1 11.9 88.9 21.9 14.2 11.3 4.9 10.8 116.2 11.9 10.3 12.3 10.3 0.0 0.0 19.2 0.2 9.4 0.2 0.2 0.0 0.9 3.2 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 7.4 0.0 0.0 0.6 0.8 0.0 0.0 0.0 1.0 6.5 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 12.8 11.0 18.6 10.3 11.2 14.1 10.9 15.4 11.9 11.3 10.3 13.8 0.0 0.5 1.0 0.8 8.2 0.4 0.2 0.6 39.8 7.8 18.7 2.9 0.0 1.4 0.0 33.3 5.3 0.5 2.1 0.0 0.1 0.3 0.5 1.4 18.5 1.2 0.0 2.7 8.2 3.8 97.8 9.7 0.9 0.0 0.5 3.6 1.0 7.8 26.9 7.7 137.4 0.0 0.8 3.7 2.8 3.7 0.5 245.5 25.3 0.0 3633.8 0.0 8.5 1.7 0.2 0.8 14.7 5.8 1.8 1.3 0.2 0.2 124.4 276.1 41.9 157.1 0.2 0.1 0.6 3.1 12.4 1.5 22.9 3.4 0.6 FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 352.1;Fibroblasts: 521.9;Leydig cells: 327.4;Peritubular cells: 270.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 1782.4;BJ: 2156.3;fHDF/TERT166: 2692.9;HBF TERT88: 1741.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 34000000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA035251: AB_10601906, HPA040815: AB_2732489" "unprognostic (2.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.84e-2)" "unprognostic (4.54e-3)" "unprognostic (4.10e-2)" "unprognostic (1.35e-1)" "unprognostic (9.88e-2)" "unprognostic (3.05e-2)" "unprognostic (1.19e-2)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (4.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.05e-2)" "unprognostic (4.47e-3)" 432.4 134.3 20.5 116.3 18.1 2.2 166.1 22.8 22.7 279.9 83.0 156.4 37.1 157.5 50.8 126.1 150.6 257.0 242.7 20.6 22.8 45.4 35.7 120.7 50.3 28.5 44.6 90.3 37.3 35.5 25.7 442.0 23.1 188.3 90.4 29.8 59.3 184.4 31.8 64.2 69.1 409.6 22.7 63.1 68.6 33.5 22.7 24.2 78.8 89.8 38.8 260.4 104.3 20.6 81.0 21.2 222.9 91.8 1304.4 1782.4 1.3 2156.3 1208.9 1374.5 1211.0 0.1 178.5 0.8 178.8 2692.9 112.8 20.5 68.6 270.0 1741.5 1.1 32.5 0.4 159.8 0.3 286.0 1.2 0.9 1362.7 8.5 884.5 192.7 612.1 811.6 11.2 0.5 0.3 227.6 0.5 22.6 2.0 181.3 0.4 181.9 0.7 92.7 1.0 150.4 1.7 39.2 93.5 764.6 13.6 76.5 462.6 23.5 6.2 986.8 507.4 479.8 268.0 323.8 1.0 1.1 2.3 177.4 0.9 67.0 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 2.6 20.5 18.1 22.8 22.7 20.6 22.8 28.5 44.6 23.1 22.7 22.7 20.6 76.9 64.1 9.4 56.5 1.1 64.1 31.9 36.4 10.2 2.3 25.6 24.6 127.5 8.6 42.5 23.9 0.0 114.4 2.5 0.9 0.0 62.6 2.3 44.4 176.7 111.4 3.0 3.6 9.6 5.8 352.1 521.9 3.1 23.0 1.3 66.5 142.5 17.4 20.6 1.7 16.2 0.2 8.2 10.8 91.6 9.8 327.4 11.5 110.3 30.0 9.9 116.1 0.0 9.5 0.9 117.8 0.7 270.8 0.9 108.4 0.0 5.5 74.9 4.3 59.2 62.5 129.3 1.5 4.4 2.2 48.2 54.7 7.1 47.5 0.9 65.3 FSTL4 KIAA1061 ENSG00000053108 "Follistatin like 4" Q6MZW2 5 133196455-133612541 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.4" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 390.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SCLC-21H: 57.2;U-266/70: 19.3;U-266/84: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045920 Uncertain Uncertain Mitochondria "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA045920: AB_10965844" "unprognostic (5.52e-2)" "unprognostic (2.54e-1)" "unprognostic (5.74e-2)" "unprognostic (8.14e-2)" "unprognostic (1.87e-1)" "unprognostic (3.97e-2)" "unprognostic (6.35e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (4.74e-2)" "unprognostic (8.66e-2)" "unprognostic (3.73e-4)" "unprognostic (2.02e-2)" "unprognostic (9.91e-3)" "unprognostic (1.03e-2)" "unprognostic (4.25e-2)" 0.1 1.3 5.5 0.6 5.5 1.9 0.6 8.5 11.2 0.3 0.0 1.1 0.7 0.2 1.5 1.9 0.9 0.5 0.3 3.1 3.2 2.8 0.1 1.2 0.3 0.0 6.2 0.4 1.9 3.1 2.3 3.8 0.0 1.6 1.1 3.9 0.7 0.0 0.9 3.4 0.8 0.2 0.0 0.4 1.4 1.7 21.4 1.3 0.8 0.5 1.1 6.0 0.9 7.8 7.5 13.1 1.4 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 12.5 1.7 0.7 10.5 0.0 1.3 0.2 1.7 0.5 0.0 0.9 0.6 0.6 13.9 1.1 0.0 0.0 0.7 0.3 1.8 0.0 0.1 0.3 0.0 0.5 5.9 7.0 0.0 12.7 1.5 0.6 14.4 14.2 1.6 0.6 1.3 14.1 0.0 15.0 57.2 1.6 2.9 2.4 0.3 12.2 4.6 0.5 0.3 0.6 2.4 0.8 0.4 19.3 20.7 0.5 0.2 0.1 0.4 1.1 0.2 0.1 0.2 0.0 0.5 0.6 0.4 0.3 0.1 0.5 0.4 0.2 0.5 0.2 0.2 0.3 0.3 0.3 5.5 5.5 8.5 11.2 3.1 3.2 0.0 6.2 0.0 0.0 21.4 7.8 0.0 0.0 3.1 21.5 1.0 1.7 2.5 0.2 4.0 10.1 0.6 0.3 9.6 0.0 4.4 0.0 14.6 0.4 0.1 0.0 0.0 0.2 35.9 1.2 0.2 0.6 9.0 0.0 390.3 0.0 0.0 0.4 0.0 0.1 0.0 1.4 0.0 0.0 0.1 1.7 57.9 0.4 0.0 0.0 0.0 20.4 0.3 1.2 10.6 8.4 0.0 3.0 0.0 21.1 4.5 0.6 0.0 0.7 0.0 0.4 0.2 2.5 3.7 2.6 6.6 0.0 1.1 0.5 0.7 3.3 1.6 0.0 0.4 0.9 0.1 2.9 FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494812-143511720 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 165.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" NA NA 56000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA031659: AB_10600661, HPA031661: AB_10601681" "unprognostic (1.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (2.70e-9)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (7.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-3)" "unprognostic (9.18e-2)" "unprognostic (2.69e-1)" "unprognostic (7.25e-2)" "unprognostic (5.07e-2)" 28.9 41.4 13.5 25.4 16.4 25.8 26.3 16.0 15.3 29.2 30.2 41.5 42.6 25.6 44.9 14.2 23.7 27.8 27.9 12.4 16.5 54.8 52.3 28.9 17.2 17.1 14.2 30.4 34.6 165.8 15.8 50.5 17.8 21.9 52.8 6.1 25.4 25.8 6.9 12.3 39.3 27.6 16.4 24.6 38.3 12.6 15.9 6.6 32.0 11.6 17.0 33.5 20.4 20.9 97.4 55.7 47.6 86.9 69.0 134.4 90.1 89.9 95.4 108.1 182.0 107.1 94.8 0.2 66.1 120.8 33.9 0.6 24.1 11.7 148.9 87.2 92.6 32.6 100.1 163.2 99.3 0.3 15.8 72.3 69.4 96.6 41.5 91.6 111.4 0.2 117.6 49.3 123.2 114.6 0.2 75.9 62.1 44.2 76.0 0.2 99.7 72.1 129.0 59.5 36.0 23.6 98.7 65.3 82.3 36.3 32.1 79.6 65.9 64.1 54.0 161.6 175.4 18.3 21.3 0.7 74.1 59.1 22.5 38.8 84.9 26.2 13.2 84.0 15.0 11.3 9.8 11.3 65.4 8.3 4.4 7.9 5.5 29.6 62.0 10.3 19.8 51.9 13.5 16.4 16.0 15.3 12.4 16.5 17.1 14.2 17.8 16.4 15.9 20.9 27.3 41.7 35.9 9.1 13.5 11.2 12.6 30.3 9.1 3.7 19.2 12.6 28.0 38.6 37.9 25.8 0.0 52.5 10.3 47.6 11.7 81.9 2.0 26.8 55.2 25.0 9.6 18.7 8.7 124.9 109.8 62.6 34.7 28.9 37.4 38.1 23.6 35.2 110.3 1.7 11.8 38.1 46.8 57.5 29.2 2.6 66.8 51.7 42.7 9.4 49.1 11.1 13.4 5.5 14.5 74.6 38.2 45.5 47.7 13.8 60.3 51.4 34.8 1.1 6.6 33.8 35.0 4.8 4.6 13.2 8.0 46.4 11.5 78.8 50.4 18.4 FUT10 ENSG00000172728 "Fucosyltransferase 10" Q6P4F1 8 33370824-33473146 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 140.0;Early spermatids: 248.8;Late spermatids: 334.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053970, HPA058655" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Endoplasmic reticulum, Golgi apparatus" "HPA053970: AB_2682327, HPA058655: AB_2683789" "unprognostic (6.02e-2)" "unprognostic (4.61e-2)" "unprognostic (2.85e-3)" "unprognostic (6.24e-2)" "unprognostic (1.01e-1)" "unprognostic (4.80e-2)" "unprognostic (5.40e-3)" "unprognostic (6.07e-2)" "unprognostic (2.84e-1)" "unprognostic (2.23e-1)" "unprognostic (9.10e-3)" "unprognostic (2.76e-4)" "unprognostic (3.06e-3)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-3)" "unprognostic (6.01e-3)" 1.9 2.2 4.3 1.0 4.7 0.8 3.4 4.2 4.2 4.0 2.0 2.5 2.5 3.1 1.2 1.9 3.3 1.8 1.7 3.0 3.3 3.1 2.0 2.4 1.8 4.3 5.5 5.2 2.6 5.1 1.3 3.5 3.3 2.2 2.7 5.2 2.7 2.1 0.6 3.2 2.6 2.9 2.7 1.5 2.3 1.5 4.8 2.9 2.8 1.2 2.2 2.2 2.2 2.5 2.4 4.5 6.8 8.3 10.8 10.8 3.4 4.3 7.1 4.2 5.4 6.3 3.6 2.7 5.1 5.8 3.5 5.9 10.4 4.1 4.1 5.8 3.8 8.6 3.6 7.0 4.9 1.9 2.9 8.0 7.0 1.1 5.4 8.8 8.6 4.4 8.0 3.2 3.9 1.4 6.6 2.8 9.1 6.4 3.0 4.8 5.1 1.4 6.1 5.4 2.4 2.3 2.5 3.7 5.1 7.0 3.8 1.9 6.6 3.2 1.4 8.1 3.6 1.3 2.2 1.8 2.0 5.4 3.4 0.4 0.6 0.7 1.3 0.2 1.4 1.0 0.7 1.2 1.3 0.3 0.8 0.8 0.4 1.6 0.2 0.7 1.7 0.6 4.3 4.7 4.2 4.2 3.0 3.3 4.3 5.5 3.3 2.7 4.8 2.5 4.5 3.2 2.0 140.0 2.5 2.7 2.7 3.4 4.0 2.9 3.7 3.8 2.5 2.8 3.2 3.7 10.4 12.0 3.0 1.5 1.9 4.5 248.8 2.8 5.7 3.8 3.6 3.8 16.3 4.0 7.0 5.8 6.1 3.0 5.7 10.1 5.3 3.6 3.4 3.3 20.2 3.2 4.1 2.2 1.8 334.2 6.8 2.2 1.8 29.0 3.0 29.9 5.2 44.2 16.4 4.0 1.0 4.9 5.0 1.4 5.3 3.0 2.0 11.0 0.0 5.7 4.6 7.0 2.7 5.5 1.7 6.0 2.6 6.5 3.6 1.3 FUT9 Fuc-TIX ENSG00000172461 "Fucosyltransferase 9" Q9Y231 6 96015974-96215612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 18.9;stomach 1: 23.2" "Cell type enhanced" "Detected in some" "Astrocytes: 776.4;Excitatory neurons: 333.5;Inhibitory neurons: 238.2;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 224.7" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.9;OE19: 2.8;RT4: 6.5;SCLC-21H: 6.3;SK-BR-3: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070923 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA070923: AB_2686323" "unprognostic (1.60e-1)" "unprognostic (2.48e-1)" "unprognostic (5.99e-3)" "unprognostic (1.33e-1)" "unprognostic (2.40e-1)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (6.43e-3)" "unprognostic (5.60e-2)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" 0.0 0.4 10.5 0.0 12.6 0.0 0.6 14.5 11.7 0.0 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 11.8 13.6 0.2 0.0 0.0 0.0 3.4 18.9 0.0 4.8 0.0 0.4 0.4 3.2 0.2 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.0 5.5 0.0 23.2 0.0 15.3 0.0 0.1 0.0 0.0 0.9 0.0 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 1.4 2.8 0.0 0.0 0.0 0.0 0.0 6.5 6.3 0.1 0.0 3.6 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 12.6 14.5 11.7 11.8 13.6 3.4 18.9 3.2 5.5 15.3 6.4 0.0 0.0 0.0 776.4 0.2 0.0 0.6 0.0 0.0 4.2 1.4 1.7 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.5 0.1 1.3 0.0 0.0 333.5 2.0 0.0 0.1 56.1 1.4 0.0 0.4 0.0 0.0 0.1 0.0 238.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.2 0.0 168.9 224.7 0.5 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.2 FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 163.9;Leydig cells: 237.9;Muller glia cells: 128.7;Peritubular cells: 363.8;Sertoli cells: 355.0;Theca cells: 141.8" "Cancer enriched" "Detected in all" 6 "glioma: 71.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cell line enhanced" "Detected in some" "AF22: 136.0;HAP1: 92.9;RH-30: 57.1;SCLC-21H: 204.5;SH-SY5Y: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA041334: AB_10970752, HPA042284: AB_2677931" "unprognostic (2.18e-3)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.31e-2)" "unprognostic (1.15e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "prognostic favorable (5.97e-4)" "unprognostic (3.44e-2)" "prognostic favorable (4.38e-5)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.60e-4)" 58.4 116.3 230.8 30.1 258.5 9.8 39.5 82.5 293.2 112.3 28.1 371.1 22.2 321.5 61.0 29.8 181.6 93.1 117.1 244.3 187.3 70.6 32.8 86.6 30.0 91.8 173.6 281.1 30.1 9.8 175.0 16.7 149.5 107.8 35.9 47.1 29.5 73.2 37.3 22.2 104.6 197.6 71.4 151.9 98.9 86.6 136.4 31.2 66.5 78.3 18.9 202.9 80.4 179.3 0.3 0.9 136.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.1 4.8 0.7 92.9 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.3 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.2 2.6 0.0 1.7 6.3 0.5 27.2 0.0 0.0 0.1 57.1 1.0 3.5 0.1 204.5 114.0 0.0 0.5 5.1 36.9 2.4 2.4 0.0 0.0 30.0 0.5 0.0 0.4 0.3 0.1 1.0 0.4 0.4 0.0 37.7 0.0 0.0 9.4 0.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.9 0.0 0.1 0.6 0.0 9.9 230.8 258.5 82.5 293.2 244.3 187.3 91.8 173.6 149.5 71.4 136.4 179.3 72.2 6.4 2.2 0.0 1.1 6.6 2.4 1.1 0.6 3.5 2.1 21.5 9.3 1.5 0.7 0.0 2.1 0.8 1.0 0.0 1.9 6.4 3.6 0.6 23.9 71.8 12.5 10.7 0.0 0.4 1.1 78.6 0.5 1.0 0.0 29.7 163.9 1.6 72.7 1.7 0.0 0.2 6.1 32.4 9.6 14.3 237.9 18.7 16.0 0.0 9.8 128.7 1.0 0.0 0.0 0.4 0.0 363.8 1.2 4.9 0.0 0.1 1.7 4.4 355.0 49.6 79.6 4.6 3.5 1.4 3.8 1.4 1.4 141.8 0.0 1.7 FYB1 "ADAP, FYB, FYB-120/130, SLAP-130" ENSG00000082074 "FYN binding protein 1" O15117 5 39105252-39274528 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.0;lymphoid tissue: 112.8" "Cell type enhanced" "Detected in many" "dendritic cells: 142.9;Extravillous trophoblasts: 88.7;Hofbauer cells: 157.0;Macrophages: 104.2;T-cells: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1670.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HEL: 61.5;JURKAT: 211.9;MOLT-4: 212.9;REH: 61.3;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025336, HPA026796, HPA067427" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 6200000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB025336: , HPA026796: AB_10964126, HPA067427: " "unprognostic (5.65e-2)" "unprognostic (2.92e-2)" "unprognostic (1.56e-2)" "unprognostic (6.26e-2)" "unprognostic (4.08e-1)" "unprognostic (3.29e-2)" "unprognostic (2.60e-1)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (5.63e-2)" "unprognostic (5.35e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (2.40e-1)" "unprognostic (4.14e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-1)" 10.2 5.8 5.7 82.5 5.5 53.0 5.1 6.3 9.3 6.6 7.4 10.0 9.1 3.8 10.5 5.7 3.6 16.8 2.4 5.4 7.9 5.0 13.6 17.6 85.8 16.7 19.1 2.7 1.8 2.1 1.5 17.9 15.8 4.2 11.0 0.5 7.4 3.0 1.2 2.0 15.0 11.6 9.3 73.0 12.2 3.3 13.3 112.8 2.6 2.7 63.0 17.1 1.8 13.9 0.2 4.2 0.0 0.0 0.5 0.0 21.1 0.1 1.2 0.3 0.4 0.4 0.3 0.3 0.0 0.0 8.0 16.4 0.0 0.3 0.1 0.3 0.0 61.5 0.0 0.1 0.0 23.3 18.6 0.3 0.4 0.0 0.4 0.1 0.0 211.9 0.0 0.0 0.0 0.0 212.9 13.5 0.2 0.1 0.1 61.3 0.0 0.3 1.0 3.5 0.1 0.0 0.1 0.5 6.5 1.4 0.0 5.2 0.0 0.0 0.2 0.2 0.2 0.4 0.0 4.5 0.0 81.4 0.2 151.3 359.0 354.6 76.3 406.5 52.9 1.8 216.7 134.5 127.6 1.3 271.7 169.8 1670.8 89.9 483.9 30.8 231.5 400.1 5.7 5.5 6.3 9.3 5.4 7.9 16.7 19.1 15.8 9.3 13.3 13.9 4.4 16.0 24.7 0.0 6.2 0.0 0.0 0.0 0.0 0.0 3.2 7.6 0.0 0.0 5.6 14.7 0.0 28.8 142.9 0.0 9.8 0.4 0.0 0.7 1.1 4.3 0.0 0.0 0.0 0.0 88.7 3.8 0.0 1.0 15.2 0.1 0.0 0.0 157.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 35.9 3.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 40.2 119.3 0.1 0.0 0.0 FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 44.9;Cholangiocytes: 45.8;Horizontal cells: 141.3;Peritubular cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Cell line enhanced" "Detected in many" "AF22: 24.8;HSkMC: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favorable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" 5.4 4.4 2.4 2.7 2.5 1.1 10.7 5.8 2.4 9.9 11.1 5.9 5.1 8.6 4.3 5.2 5.5 5.7 12.7 4.7 2.9 9.6 2.5 10.7 1.3 2.5 6.2 10.1 4.7 2.4 3.9 10.0 2.3 10.3 3.7 2.0 9.0 16.4 1.9 10.4 5.1 5.3 2.3 3.2 4.6 1.6 3.4 1.8 20.5 2.4 1.3 6.4 11.2 2.0 0.8 2.5 24.8 2.6 19.8 17.0 4.5 9.2 5.8 3.3 2.3 1.1 4.3 0.0 2.2 5.9 4.2 4.7 3.9 2.0 2.2 0.0 4.9 0.2 4.6 1.3 1.4 4.2 1.0 32.3 3.6 7.6 2.4 12.6 0.7 2.8 1.5 3.6 9.7 6.2 0.8 1.1 6.4 1.3 4.2 5.1 15.3 0.4 5.3 11.8 3.4 6.5 7.0 5.6 1.6 5.7 3.0 3.8 3.8 13.9 10.4 15.0 3.8 3.3 2.5 0.4 15.0 3.5 16.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.2 2.4 2.5 5.8 2.4 4.7 2.9 2.5 6.2 2.3 2.3 3.4 2.0 5.7 3.2 1.5 4.6 1.1 4.2 44.9 7.0 10.8 1.6 27.7 29.5 18.5 45.8 4.6 12.9 2.1 3.4 0.6 7.4 0.0 4.3 0.3 12.0 13.1 4.5 3.5 0.8 0.6 2.0 2.2 18.5 2.0 15.7 12.7 1.8 15.4 0.9 3.5 141.3 1.0 3.0 4.1 17.4 16.2 1.1 33.2 14.3 17.8 1.9 4.6 3.0 1.0 1.0 0.2 1.9 4.8 45.1 0.4 11.7 6.0 11.6 2.4 2.9 0.0 6.2 10.3 0.5 3.7 9.1 5.1 2.1 0.6 2.6 4.6 7.3 FZD3 ENSG00000104290 "Frizzled class receptor 3" Q9NPG1 8 28494205-28574267 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 14.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 98.0;Excitatory neurons: 155.9;Inhibitory neurons: 82.3;Rod photoreceptor cells: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.3" "Group enriched" "Detected in many" 5 "dendritic cells: 9.3;T-cells: 2.3" "Cell line enhanced" "Detected in many" "AF22: 53.2;Karpas-707: 27.9;SCLC-21H: 39.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024995, HPA042320" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "CAB024995: , HPA042320: AB_2677948" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "prognostic favorable (1.17e-4)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (2.57e-4)" "unprognostic (1.69e-2)" "unprognostic (4.26e-4)" "unprognostic (2.11e-1)" "prognostic favorable (3.71e-4)" "unprognostic (2.86e-2)" "unprognostic (1.68e-2)" "unprognostic (1.09e-2)" "unprognostic (1.38e-1)" "unprognostic (4.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.09e-3)" 1.0 2.9 5.2 1.5 6.7 1.5 2.3 5.7 9.9 2.4 13.8 2.2 1.3 3.4 6.9 1.9 3.5 1.3 1.1 6.8 4.0 2.6 0.6 1.0 2.1 1.8 5.4 7.0 3.5 4.2 3.8 1.3 4.2 4.3 1.2 14.7 3.3 5.5 1.2 1.5 1.0 2.4 0.9 0.6 2.5 5.0 3.2 1.8 3.4 1.3 1.4 1.9 1.6 2.6 14.8 3.1 53.2 10.2 0.0 0.8 7.9 0.5 1.1 3.0 1.3 3.1 3.1 6.9 2.6 0.3 6.6 5.2 8.0 8.8 2.1 9.1 5.8 4.8 1.0 2.0 0.0 2.7 7.9 0.6 4.1 0.2 2.3 0.6 0.6 7.3 3.5 27.9 0.1 3.7 0.2 5.8 13.3 6.4 4.6 3.3 8.0 6.8 4.0 4.4 39.6 10.7 2.9 7.5 8.7 7.0 7.4 4.0 0.0 0.0 14.3 2.0 3.7 5.1 6.1 6.7 4.2 0.0 2.7 0.7 0.2 0.0 1.6 0.2 2.1 1.1 1.2 2.3 0.9 0.6 1.6 1.6 0.1 0.9 0.0 9.3 0.0 0.7 5.2 6.7 5.7 9.9 6.8 4.0 1.8 5.4 4.2 0.9 3.2 2.6 1.7 9.6 12.0 65.6 5.6 6.6 7.9 17.0 10.8 28.1 21.6 11.7 6.0 4.3 17.7 9.2 98.0 10.5 15.7 1.4 1.9 12.1 25.7 24.2 18.7 4.3 28.7 5.0 155.9 14.9 9.7 8.8 8.2 27.7 5.7 29.3 8.6 3.0 4.2 21.9 82.3 6.3 8.2 1.0 7.4 11.9 48.1 2.1 33.8 14.0 0.7 17.0 2.1 52.8 14.3 11.8 3.4 51.1 17.2 14.1 0.8 11.4 17.5 87.1 26.3 8.6 15.0 58.4 45.6 5.6 4.7 4.8 5.0 15.0 5.4 7.7 FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 30.9;Breast myoepithelial cells: 37.0;Cardiomyocytes: 21.1;Fibroblasts: 23.5;Proximal enterocytes: 21.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 42.8;BJ hTERT+: 48.4;CAPAN-2: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" 10.2 3.0 4.9 5.6 4.7 0.4 15.5 30.2 4.3 13.2 6.3 36.7 6.9 18.4 14.1 9.4 16.8 6.3 14.4 8.8 5.0 8.2 1.2 5.3 3.9 5.2 4.9 25.0 1.7 1.1 9.3 5.7 5.5 19.2 5.5 1.3 21.7 23.5 26.7 10.9 10.8 11.1 4.9 1.9 5.9 2.1 4.5 1.1 5.1 9.5 3.8 27.1 15.3 5.6 10.3 5.2 33.2 10.8 10.6 7.9 14.8 42.8 48.4 11.9 13.9 32.2 62.7 0.1 25.1 26.2 7.9 10.6 6.0 1.3 13.7 5.4 8.6 1.1 2.1 2.7 7.2 2.1 2.1 7.6 1.0 6.4 3.7 9.5 0.0 0.7 2.9 2.6 9.8 4.2 0.0 5.7 36.6 2.0 3.5 4.2 6.4 1.1 1.9 6.1 5.5 12.6 5.4 0.4 6.8 26.7 3.8 2.5 0.1 23.8 8.8 15.0 5.4 2.7 2.2 0.1 4.9 0.5 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.7 30.2 4.3 8.8 5.0 5.2 4.9 5.5 4.9 4.5 5.6 3.5 0.0 8.1 3.6 2.0 10.3 8.3 1.9 14.8 0.0 30.9 37.0 21.1 1.5 0.3 1.8 0.0 0.5 2.0 4.7 1.9 1.6 0.1 1.5 2.0 1.7 1.2 0.0 1.5 0.2 1.1 23.5 2.6 3.6 1.3 7.5 0.7 0.7 1.5 0.0 0.2 9.9 0.0 0.8 5.7 0.5 5.3 2.0 3.6 0.0 0.1 7.5 0.0 0.0 0.1 0.6 2.1 4.9 1.7 6.9 21.3 0.1 0.9 0.6 6.6 13.5 16.3 1.6 2.9 11.4 9.8 0.8 2.5 0.5 7.6 1.8 G0S2 ENSG00000123689 "G0/G1 switch 2" P27469 1 209675412-209676390 "Metabolic proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 796.7;bone marrow: 1345.4" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 5188.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 44.5" "Immune cell enriched" "Detected in some" 60 "neutrophil: 549.5" "Lineage enriched" "Detected in many" 213 "granulocytes: 549.5" "Cell line enhanced" "Detected in many" "ASC diff: 460.8;HBEC3-KT: 726.2;PC-3: 180.6;RPMI-8226: 242.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "unprognostic (1.67e-3)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (3.82e-1)" "unprognostic (2.21e-1)" "unprognostic (5.04e-3)" "unprognostic (3.03e-1)" "unprognostic (1.38e-1)" "unprognostic (2.32e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (7.57e-3)" "unprognostic (1.53e-2)" "unprognostic (4.78e-2)" "unprognostic (2.64e-1)" 796.7 194.3 7.0 95.7 7.5 1345.4 519.5 7.4 44.5 9.2 8.2 20.9 7.6 34.3 11.7 8.6 26.8 15.7 175.9 8.8 6.8 262.6 664.6 318.4 7.6 7.4 8.6 47.5 31.0 0.8 9.5 13.8 9.1 38.3 4.0 0.6 59.8 14.8 651.4 24.3 31.7 10.9 7.9 49.3 63.8 30.1 7.8 5.9 23.7 303.4 5.4 136.2 17.3 9.7 0.0 4.3 0.0 0.0 460.8 16.1 0.3 0.7 1.4 1.9 1.8 19.3 14.8 0.0 4.1 3.4 2.5 0.0 0.0 726.2 4.4 0.7 1.2 0.0 1.5 0.6 37.5 0.2 0.1 47.8 1.6 32.4 0.0 15.8 0.0 0.0 0.2 0.0 0.2 0.0 0.2 15.7 1.3 0.0 180.6 0.0 0.0 242.8 1.7 0.3 0.9 1.4 16.3 0.0 4.0 0.0 0.2 56.7 73.6 0.0 4.9 0.2 0.1 0.0 1.1 0.1 13.1 0.1 0.0 0.0 1.0 9.1 0.0 1.1 0.4 0.1 2.5 0.1 0.3 0.3 0.0 0.0 549.5 0.0 0.2 0.0 0.0 0.4 7.0 7.5 7.4 44.5 8.8 6.8 7.4 8.6 9.1 7.9 7.8 9.7 52.3 9.6 59.5 5.9 16.1 232.4 654.8 760.7 124.1 0.6 295.2 43.3 359.1 14.3 111.6 11.0 0.0 1.8 5.0 16.6 299.3 52.3 25.3 42.7 12.0 264.5 29.3 6.9 0.9 148.2 3.6 730.2 11.7 112.0 39.1 34.7 12.1 179.4 174.2 0.0 3.1 32.6 22.4 78.2 5188.4 12.3 114.6 1060.3 327.3 2.8 30.7 23.1 1.0 11.1 0.9 736.5 42.9 71.5 10.3 416.7 41.1 304.9 42.3 0.3 32.9 56.4 60.1 52.1 1.1 35.2 161.4 4.2 33.3 7.5 52.5 513.7 GAB1 DFNB26 ENSG00000109458 "GRB2 associated binding protein 1" Q13480 4 143336762-143474568 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 114.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 162.7;Microglial cells: 192.0;Oligodendrocyte precursor cells: 288.0;Oligodendrocytes: 1013.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 74.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034333, HPA066404" Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli fibrillar center, Plasma membrane" Cytosol "CAB034333: AB_2107855, HPA066404: " "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "unprognostic (1.66e-1)" "unprognostic (4.71e-2)" "unprognostic (1.79e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-1)" "unprognostic (1.35e-2)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.20e-1)" "prognostic favorable (3.91e-5)" "unprognostic (4.99e-2)" "unprognostic (2.70e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" 7.9 8.6 23.3 6.7 69.9 11.5 9.9 35.5 30.0 10.6 2.5 19.7 12.1 18.1 14.2 20.4 9.2 12.5 30.5 20.4 34.6 13.9 9.1 17.9 6.1 57.3 45.4 19.5 8.1 11.3 4.3 21.0 47.9 8.5 22.8 6.9 8.9 14.7 13.4 10.7 12.3 17.7 26.4 7.5 11.3 9.2 45.7 5.4 7.5 16.5 8.7 7.1 9.7 114.8 6.7 1.4 16.7 12.1 8.3 7.9 22.0 4.6 15.2 5.4 9.4 12.8 11.2 0.2 1.4 6.5 3.7 3.8 16.2 5.3 6.2 1.0 3.9 12.2 3.7 6.1 5.7 1.6 2.3 9.7 9.5 6.6 4.3 11.5 7.2 0.2 4.1 21.7 3.8 9.7 0.9 0.0 4.8 3.5 5.3 74.6 8.2 8.8 8.4 8.0 3.9 11.8 3.1 13.3 5.6 11.2 8.5 1.6 5.5 6.9 5.4 3.4 3.5 34.6 18.2 26.3 4.7 4.8 5.7 4.1 0.4 0.5 0.0 0.5 0.2 0.9 0.0 0.0 0.5 1.8 0.0 0.0 2.6 5.0 1.7 2.2 0.0 0.3 23.3 69.9 35.5 30.0 20.4 34.6 57.3 45.4 47.9 26.4 45.7 114.8 13.4 28.9 19.0 89.5 13.1 20.3 8.8 3.3 12.0 2.1 11.6 8.9 34.0 8.6 5.3 12.9 0.0 23.5 10.9 26.2 0.0 6.6 0.9 8.8 9.3 16.3 22.2 40.8 162.7 2.6 10.6 14.4 11.2 21.6 2.5 9.6 13.9 7.0 6.1 3.3 62.2 27.8 4.1 11.6 10.2 3.8 20.8 8.8 16.0 192.0 5.6 15.4 1.0 288.0 1013.6 4.9 10.7 18.8 94.4 7.2 9.3 5.4 3.4 0.8 13.1 7.0 14.3 2.0 5.3 19.9 24.9 10.4 2.7 4.4 13.6 13.5 GABRA4 ENSG00000109158 "Gamma-aminobutyric acid type A receptor subunit alpha4" P48169 4 46918900-46993581 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 7.5;heart muscle: 2.5" "Group enriched" "Detected in some" 6 "Excitatory neurons: 124.9;Inhibitory neurons: 160.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 149 "REH: 14.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.78e-2)" "unprognostic (6.57e-3)" "unprognostic (2.46e-1)" "unprognostic (2.23e-1)" "unprognostic (3.17e-1)" "unprognostic (1.11e-1)" "unprognostic (6.91e-2)" 0.0 0.0 1.8 0.0 7.5 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 2.5 4.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 7.5 0.0 6.8 4.0 2.6 0.7 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 21.5 0.0 0.5 0.0 0.0 0.6 0.3 0.0 0.6 15.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.9 0.0 1.3 0.0 0.0 0.1 0.0 0.0 124.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 160.1 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 8.4 0.0 6.1 0.0 3.5 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.4 3.8 0.1 0.4 0.1 0.0 0.0 0.0 0.9 0.0 GABRG3 ENSG00000182256 "Gamma-aminobutyric acid type A receptor subunit gamma3" Q99928 15 26971181-27541984 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 17.6;retina: 27.1;testis: 9.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 444.7;Inhibitory neurons: 615.5;Late spermatids: 351.0;Muller glia cells: 179.9" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Region enhanced" "Detected in many" "hypothalamus: 17.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.5;PC-3: 5.5;SK-MEL-30: 3.5;U-2 OS: 2.5;U-266/70: 3.2;U-87 MG: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054010 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA054010: AB_2682342" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (3.50e-2)" "unprognostic (2.61e-1)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (5.15e-2)" "unprognostic (2.95e-1)" "unprognostic (4.41e-1)" "unprognostic (1.43e-5)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" 0.0 0.4 3.5 0.2 3.0 0.0 0.4 0.0 4.2 0.8 0.0 0.0 0.0 0.1 1.9 0.0 0.4 0.0 0.0 0.9 17.6 0.7 0.1 0.0 0.6 0.5 0.2 0.0 0.0 0.0 3.0 0.0 0.0 6.6 0.0 27.1 0.8 0.2 0.0 0.3 0.0 0.0 0.6 1.0 0.0 9.3 10.2 1.0 1.5 0.0 0.8 0.0 0.2 2.9 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.4 0.3 0.0 5.5 0.0 0.0 1.0 0.0 0.0 0.1 1.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 3.2 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.0 0.0 4.2 0.9 17.6 0.5 0.2 0.0 0.6 10.2 2.9 0.1 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.0 4.6 2.5 1.4 0.9 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 86.2 3.2 0.1 0.3 0.0 0.0 444.7 0.0 0.0 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.1 0.0 615.5 0.0 0.0 0.0 0.0 351.0 0.9 0.2 0.0 7.5 0.0 179.9 0.0 16.1 7.9 0.0 0.0 0.7 0.0 3.1 0.0 0.3 0.0 4.6 0.0 0.1 0.1 1.6 7.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 GABRP ENSG00000094755 "Gamma-aminobutyric acid type A receptor subunit pi" O00591 5 170763350-170814047 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 152.3;esophagus: 171.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 169.0;Breast myoepithelial cells: 113.2;Club cells: 83.1;Endometrial ciliated cells: 146.0;Glandular and luminal cells: 464.0;Urothelial cells: 146.6" "Group enriched" "Detected in many" 4 "breast cancer: 35.4;cervical cancer: 49.3;endometrial cancer: 16.8;pancreatic cancer: 41.9;stomach cancer: 25.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.8" "Group enriched" "Detected in many" 8 "granulocytes: 11.8;monocytes: 5.7" "Cell line enhanced" "Detected in many" "A-431: 215.1;EFO-21: 236.8;HeLa: 166.8;PC-3: 331.3;SuSa: 418.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB014883 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB014883: " "unprognostic (3.98e-3)" "prognostic favorable (3.37e-4)" "unprognostic (8.34e-2)" "unprognostic (1.57e-1)" "unprognostic (8.90e-2)" "unprognostic (1.27e-1)" "unprognostic (7.89e-2)" "unprognostic (4.97e-3)" "unprognostic (3.72e-1)" "unprognostic (4.93e-3)" "unprognostic (1.30e-3)" "unprognostic (2.30e-1)" "unprognostic (1.40e-2)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (5.92e-3)" "unprognostic (6.52e-3)" 4.5 3.6 10.4 7.3 10.5 9.9 152.3 15.8 16.2 13.1 5.4 4.2 15.4 48.6 19.0 171.5 12.9 27.3 5.4 7.6 23.0 6.1 7.1 14.7 5.7 12.5 6.1 3.9 23.8 2.0 2.0 9.1 10.6 12.7 4.9 42.1 35.8 16.6 13.7 19.0 16.2 2.6 2.7 7.4 27.4 8.3 10.4 4.7 6.1 2.7 42.2 5.4 29.4 17.9 215.1 9.9 10.1 7.0 0.7 4.3 23.8 3.8 1.5 0.5 0.6 38.1 23.6 3.3 236.8 1.1 2.3 75.7 6.4 0.5 0.6 3.5 7.6 14.1 166.8 5.7 0.8 5.1 11.2 1.6 3.0 2.8 1.8 8.0 1.4 13.4 57.6 26.5 0.4 6.7 9.5 4.7 84.5 3.7 331.3 13.7 6.6 8.2 13.8 11.6 8.2 4.0 76.5 3.9 2.2 418.8 4.2 2.4 8.8 19.1 69.3 15.7 15.7 10.0 6.7 6.3 2.6 13.9 2.9 11.8 1.9 6.1 0.4 1.5 1.1 0.3 0.4 0.3 0.6 0.7 0.5 0.5 4.5 0.2 5.7 0.9 0.6 2.3 10.4 10.5 15.8 16.2 7.6 23.0 12.5 6.1 10.6 2.7 10.4 17.9 1.1 3.2 0.6 0.0 0.9 0.0 14.9 44.4 0.0 0.0 169.0 113.2 0.7 51.5 83.1 1.8 0.0 5.2 2.3 0.0 0.0 10.4 0.0 146.0 48.8 3.8 0.0 0.0 0.3 13.8 0.6 2.4 2.0 464.0 0.0 0.0 0.0 0.1 2.3 0.0 0.2 0.3 12.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 56.6 0.1 0.0 0.0 24.2 0.1 0.1 34.0 0.0 0.0 0.2 5.9 0.0 0.0 4.5 0.0 5.7 2.7 0.0 0.6 146.6 GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "brain: 645.9;pituitary gland: 885.8" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 22.2;Ductal cells: 38.9;Endometrial ciliated cells: 64.2;Endometrial stromal cells: 50.8;Exocrine glandular cells: 52.1;Extravillous trophoblasts: 48.7;Glandular and luminal cells: 26.4;Pancreatic endocrine cells: 39.5;Prostatic glandular cells: 82.5;Urothelial cells: 24.3" "Cancer enhanced" "Detected in many" "testis cancer: 22.2" "Region enriched" "Detected in many" 13 "hypothalamus: 645.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 267.2;HEK 293: 119.3;K-562: 139.5;NB-4: 493.5;SH-SY5Y: 189.6" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in all" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 60000 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 24: NB-4 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Vesicles "CAB079779: , HPA049864: AB_2680922" "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" 3.2 0.9 2.8 14.9 2.1 0.7 4.4 1.1 5.2 1.0 0.8 17.6 1.8 0.2 0.0 0.8 1.0 0.2 1.0 2.2 645.9 1.5 0.3 0.5 0.1 48.5 5.1 0.2 2.1 0.1 885.8 0.3 13.8 4.4 4.0 0.0 0.9 0.2 0.4 33.3 4.1 9.9 0.6 0.3 9.7 1.0 19.5 0.7 0.4 0.0 0.0 0.7 2.9 2.6 0.0 11.0 1.1 0.3 0.0 0.0 24.0 36.7 0.0 0.7 0.0 267.2 9.9 0.0 12.7 1.3 0.4 0.1 0.0 0.2 0.0 0.0 119.3 6.4 74.6 0.0 1.3 3.7 0.0 1.7 4.0 0.0 0.1 0.0 6.3 0.0 139.5 0.0 0.2 77.2 0.0 493.5 60.3 2.9 23.7 0.0 0.1 51.1 0.6 0.0 49.8 189.6 25.8 1.5 0.0 26.8 1.5 57.6 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.1 1.1 5.2 2.2 645.9 48.5 5.1 13.8 0.6 19.5 2.6 0.6 0.0 0.0 0.0 0.2 2.0 22.2 0.1 0.0 0.0 3.2 5.8 1.4 0.0 0.0 0.0 0.0 0.6 0.1 0.7 0.0 38.9 0.1 64.2 50.8 3.4 1.8 4.2 2.1 52.1 48.7 6.6 2.0 26.4 4.5 0.4 0.0 0.0 2.0 0.0 0.2 1.1 4.1 0.0 1.2 0.2 0.0 0.7 1.8 0.0 0.6 0.0 0.0 0.0 0.3 39.5 0.1 0.0 1.0 82.5 0.0 0.4 0.0 0.0 0.0 1.6 6.7 2.2 10.9 1.1 3.4 1.9 0.8 0.0 1.3 24.3 GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.2;Microglial cells: 23.4;Oligodendrocyte precursor cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cell line enhanced" "Detected in many" "WM-115: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Cytosol "HPA038137: AB_10697239, HPA038138: AB_2675854" "unprognostic (4.22e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (8.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (4.14e-4)" "unprognostic (3.98e-2)" "unprognostic (9.67e-2)" "unprognostic (1.89e-2)" "unprognostic (5.36e-2)" 4.3 4.9 9.2 3.9 9.3 0.7 3.7 8.4 12.6 11.0 7.6 6.1 3.8 9.1 3.1 7.8 6.0 5.6 5.0 9.1 9.5 1.4 0.9 5.2 2.9 13.4 9.5 6.3 1.4 3.0 4.2 5.1 10.1 4.8 6.3 0.5 25.6 3.6 1.9 27.7 5.0 9.9 10.7 2.7 2.4 4.8 15.9 22.3 1.9 1.9 3.2 6.7 10.6 13.1 0.1 0.9 5.4 2.3 4.7 9.6 10.9 3.2 3.2 1.8 2.6 0.6 0.2 1.1 0.7 10.4 3.3 12.2 0.3 1.8 0.6 0.1 0.6 0.4 0.2 0.4 3.4 0.3 2.7 11.7 4.6 5.5 0.6 4.0 3.7 4.3 1.6 0.2 3.4 0.4 4.2 0.2 1.9 11.5 1.3 2.7 2.4 0.2 0.0 0.4 0.3 2.2 1.0 0.0 6.7 1.0 0.0 0.3 3.4 0.3 1.6 0.5 0.1 0.2 0.2 2.5 1.9 0.4 43.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 4.5 0.3 0.0 0.1 15.0 4.6 0.3 0.2 0.1 4.7 1.3 2.2 9.2 9.3 8.4 12.6 9.1 9.5 13.4 9.5 10.1 10.7 15.9 13.1 0.7 0.0 0.5 2.9 0.1 4.2 2.0 3.3 7.4 0.0 2.2 2.4 1.0 1.5 0.9 0.0 0.0 0.3 0.3 1.5 0.0 0.6 0.2 0.2 2.1 1.2 0.0 2.7 0.5 0.0 0.4 7.5 0.0 0.3 0.0 1.2 1.4 0.0 37.2 0.0 0.3 1.3 4.1 1.3 0.8 0.0 4.7 9.6 5.4 23.4 0.7 0.4 0.0 24.6 0.5 0.3 2.5 5.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 3.7 3.3 0.6 0.3 4.2 8.1 0.8 0.7 0.1 4.1 1.4 GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 331.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA012628: AB_1849439" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" "unprognostic (2.08e-1)" "unprognostic (2.83e-2)" "unprognostic (1.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" "unprognostic (3.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (4.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.07e-2)" "unprognostic (8.60e-2)" 28.9 20.6 11.9 27.4 12.1 26.0 37.2 12.3 14.2 26.5 15.1 42.8 42.9 19.4 19.7 57.6 15.9 28.9 23.8 10.9 14.4 17.4 45.9 23.3 33.5 13.1 13.2 16.9 24.6 12.2 13.5 52.0 13.5 25.4 41.1 17.1 46.8 18.0 29.0 52.4 49.3 22.7 13.1 25.4 27.1 16.9 13.1 18.6 30.0 37.3 40.8 70.5 27.0 13.9 32.5 34.9 40.5 37.6 78.5 74.0 53.4 33.2 35.4 30.3 27.4 21.0 61.9 38.3 34.9 36.0 28.7 24.4 20.2 63.8 48.1 45.0 18.5 48.7 62.8 48.8 39.2 106.6 62.1 50.7 59.7 47.6 52.1 90.1 331.4 30.8 14.8 49.3 118.9 26.1 31.6 40.5 41.6 33.5 16.4 38.9 53.0 18.5 124.8 148.9 21.8 42.9 59.4 43.0 36.2 77.1 32.9 82.8 116.3 55.7 22.5 37.0 37.1 70.1 35.7 72.5 39.1 72.1 29.5 7.2 3.4 7.6 3.2 4.5 3.6 4.1 2.2 2.9 4.0 2.4 2.0 3.0 4.3 4.6 6.6 4.4 2.5 1.4 11.9 12.1 12.3 14.2 10.9 14.4 13.1 13.2 13.5 13.1 13.1 13.9 85.6 80.1 44.1 35.9 33.4 29.8 28.4 28.8 22.2 31.3 77.2 43.8 43.3 48.6 39.9 16.5 12.5 31.0 44.8 109.1 7.9 42.6 1.4 77.6 44.7 41.7 38.9 30.9 57.5 39.9 92.7 49.8 26.0 73.0 20.3 51.7 35.7 71.3 77.9 85.8 56.3 59.0 16.2 58.8 37.1 2.9 19.0 56.7 19.6 57.1 41.3 105.9 28.8 54.3 56.8 58.5 51.4 18.0 36.7 54.4 76.8 22.0 33.5 28.5 13.1 55.2 28.7 6.5 12.2 26.3 82.1 33.2 33.7 50.3 85.3 52.8 GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 157.4;brain: 141.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.9;Astrocytes: 34.6;Early spermatids: 26.6;Endothelial cells: 26.9;Hepatic stellate cells: 41.7;Muller glia cells: 47.4;Oligodendrocytes: 69.3" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "ASC diff: 133.0;ASC TERT1: 128.8;HSkMC: 102.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 40000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" 157.4 4.9 45.1 1.7 55.8 2.7 87.2 62.5 49.3 12.3 14.4 21.7 3.0 11.4 11.9 12.4 24.9 5.6 18.1 47.9 90.8 11.8 4.0 9.4 4.1 137.6 60.4 22.3 3.6 2.4 3.5 32.3 130.8 6.0 3.9 13.4 25.5 4.7 36.3 41.7 21.2 7.0 102.4 12.3 15.3 9.1 62.8 4.0 18.3 35.3 1.3 33.0 22.8 141.7 0.4 1.3 0.9 1.0 133.0 128.8 0.3 3.4 2.5 0.4 1.3 0.0 0.5 0.5 1.9 7.8 2.3 0.8 0.5 1.4 2.0 0.6 1.4 1.1 1.9 0.0 7.4 1.5 0.4 102.8 0.0 1.2 1.8 2.4 2.8 0.7 0.2 3.0 1.1 1.9 0.0 2.1 0.5 0.8 1.1 0.3 1.1 24.1 0.5 0.5 0.4 0.3 0.4 1.0 0.6 0.6 0.7 1.8 3.9 0.6 4.3 26.8 0.6 1.4 5.1 1.4 2.5 0.4 0.4 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 45.1 55.8 62.5 49.3 47.9 90.8 137.6 60.4 130.8 102.4 62.8 141.7 103.9 0.0 1.7 34.6 0.1 0.5 0.4 0.0 0.0 3.8 1.1 0.9 2.8 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 26.6 0.5 3.3 26.9 0.0 0.0 4.9 0.0 0.1 24.7 0.0 1.0 1.3 0.1 41.7 1.8 0.1 0.0 3.9 0.0 0.0 0.8 2.1 16.7 1.8 0.5 0.0 22.5 0.1 47.4 0.0 5.0 69.3 0.2 0.0 0.7 1.8 2.1 0.0 0.1 0.0 3.2 0.0 7.3 2.1 25.5 0.5 0.1 0.9 0.0 0.2 0.3 0.0 0.3 GALNT7 GALNAC-T7 ENSG00000109586 "Polypeptide N-acetylgalactosaminyltransferase 7" Q86SF2 4 173168811-173323967 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 143.4;Inhibitory neurons: 172.0;Intestinal goblet cells: 126.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064243, HPA065317" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 6200000 "Cluster 5: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" Nucleoplasm "HPA064243: AB_2685223, HPA065317: AB_2685465" "unprognostic (1.81e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.53e-4)" "unprognostic (1.37e-3)" "unprognostic (1.48e-1)" "unprognostic (6.86e-3)" "unprognostic (2.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.85e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (7.65e-4)" "unprognostic (1.33e-1)" "unprognostic (4.66e-3)" "unprognostic (3.05e-1)" "unprognostic (3.19e-1)" "unprognostic (2.34e-3)" "unprognostic (5.97e-2)" 6.4 6.4 6.4 16.3 8.8 11.5 23.3 34.2 8.3 25.1 3.5 47.8 29.1 16.9 7.0 14.9 9.8 15.6 5.9 6.6 7.8 7.8 2.9 9.6 12.2 12.6 8.3 11.2 22.2 8.7 5.2 13.0 11.7 39.7 52.8 22.4 27.4 8.1 1.4 3.9 33.7 16.7 10.1 11.0 65.7 11.9 8.4 60.0 13.5 3.9 9.8 17.0 5.9 16.0 71.1 37.2 35.0 11.2 18.6 27.1 50.3 18.1 20.5 16.7 23.0 11.5 109.9 39.4 13.3 16.6 45.2 59.2 15.0 32.0 22.7 154.3 29.1 47.8 72.2 0.4 12.2 71.6 32.8 17.5 28.3 37.6 18.9 63.4 112.3 28.2 32.6 59.3 86.0 23.5 52.7 39.4 34.8 70.2 24.0 52.1 32.4 10.2 123.2 32.8 28.2 21.5 8.5 50.4 25.4 45.3 20.2 21.0 135.6 11.9 52.3 0.6 40.0 17.2 0.2 20.8 48.6 42.3 43.6 13.2 14.3 18.9 5.1 7.5 7.2 6.2 5.7 5.3 12.4 3.3 4.4 3.3 21.3 7.5 8.0 5.0 9.2 6.4 6.4 8.8 34.2 8.3 6.6 7.8 12.6 8.3 11.7 10.1 8.4 16.0 10.0 6.4 38.0 72.8 12.1 1.8 9.0 12.3 4.0 47.9 41.1 19.8 9.6 8.6 36.0 20.2 2.1 1.4 16.4 143.4 0.0 14.4 2.5 28.3 13.3 11.3 22.8 12.0 74.4 48.9 3.7 12.1 102.4 52.9 24.1 14.8 12.1 0.2 10.3 10.1 172.0 126.8 24.4 17.9 6.2 4.2 9.3 17.2 8.8 62.8 16.3 8.1 5.2 71.4 54.1 39.9 50.0 5.3 6.6 52.8 63.7 10.0 17.4 25.5 13.1 16.1 11.7 3.8 5.5 14.9 1.1 0.8 9.9 13.1 48.6 19.4 GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 31.3;testis: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 95.2;Intestinal goblet cells: 47.0;Late spermatids: 150.2" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.2;glioma: 1.8;pancreatic cancer: 0.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 23.4;U-266/84: 7.6" "Not detected" "Not detected" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA No "Cluster 22: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: AB_2686604" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" 0.4 0.6 3.2 1.8 3.3 0.0 0.6 2.7 5.1 0.5 2.0 14.0 5.7 0.3 0.1 0.1 0.6 0.0 2.5 3.2 2.8 0.4 0.2 0.3 0.2 3.4 3.2 0.7 0.2 0.0 2.8 0.1 3.3 0.4 31.3 0.2 0.4 0.3 0.1 0.2 12.6 0.8 2.9 0.5 0.5 13.5 3.3 0.0 0.2 0.0 0.0 0.4 0.3 4.1 0.0 0.0 0.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 23.4 0.0 0.0 0.0 0.1 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 3.2 3.3 2.7 5.1 3.2 2.8 3.4 3.2 3.3 2.9 3.3 4.1 0.1 6.4 0.5 1.3 0.5 0.0 0.0 0.1 0.6 2.1 0.1 2.3 4.5 0.0 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 95.2 0.5 0.1 0.5 6.6 0.0 1.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 47.0 0.0 0.0 0.0 150.2 1.5 0.1 0.0 3.7 0.2 0.5 0.0 15.1 7.4 0.2 0.6 2.6 0.0 0.1 1.0 1.0 0.0 0.6 6.6 0.7 0.1 12.3 8.3 0.0 0.0 0.0 0.8 0.3 2.2 0.0 GALNTL6 "GalNAc-T6L, GALNT17" ENSG00000174473 "Polypeptide N-acetylgalactosaminyltransferase like 6" Q49A17 4 171812254-173041559 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 7.8;lymphoid tissue: 2.5" "Group enriched" "Detected in some" 17 "Excitatory neurons: 424.4;Inhibitory neurons: 1567.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 8 "B-cells: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031019 Uncertain "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA031019: AB_10601653" "unprognostic (6.84e-2)" "unprognostic (1.28e-1)" "unprognostic (2.01e-2)" "unprognostic (5.73e-2)" "unprognostic (7.50e-2)" "unprognostic (8.32e-2)" "unprognostic (3.25e-1)" "unprognostic (9.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (2.80e-1)" "unprognostic (1.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-2)" "unprognostic (4.84e-3)" "unprognostic (1.73e-2)" 0.0 0.2 3.6 0.4 2.8 0.4 0.2 0.5 4.0 1.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.1 6.0 7.8 0.0 0.1 0.1 0.3 0.2 5.3 0.0 0.1 0.0 0.0 0.0 2.3 0.7 0.2 1.3 0.3 0.0 0.3 0.1 0.5 0.0 1.1 2.5 1.0 2.4 4.0 0.0 0.1 1.4 0.1 0.1 0.4 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.5 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 2.8 0.5 4.0 6.0 7.8 0.2 5.3 2.3 1.1 4.0 0.6 0.0 0.0 1.5 10.4 2.4 0.3 0.1 0.0 0.0 1.6 0.3 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 13.5 0.0 0.0 0.1 0.0 0.0 424.4 4.1 0.0 0.3 2.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 1567.9 2.6 0.0 1.6 0.0 21.1 0.3 0.9 5.4 13.1 0.0 0.1 0.0 57.3 9.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 1.2 0.2 1.6 1.6 0.0 0.3 0.0 0.0 0.1 0.4 0.1 GAMT "PIG2, TP53I2" ENSG00000130005 "Guanidinoacetate N-methyltransferase" Q14353 19 1397026-1401570 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 615.1;skeletal muscle: 1234.9;tongue: 466.4" "Group enriched" "Detected in many" 4 "Hepatocytes: 718.3;Proximal tubular cells: 417.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 173.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 176.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051806 Approved NA NA 420000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051806: AB_2681619" "unprognostic (3.25e-1)" "unprognostic (7.74e-3)" "unprognostic (3.22e-2)" "unprognostic (6.32e-2)" "unprognostic (4.35e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (3.41e-2)" "unprognostic (7.10e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (1.54e-2)" 14.0 26.6 69.4 4.5 74.5 8.8 15.6 68.6 79.1 16.5 53.4 10.9 3.2 10.0 141.9 23.0 14.7 9.9 98.1 67.3 67.1 72.0 615.1 8.1 7.7 71.8 68.3 22.8 229.8 37.8 37.4 4.9 70.4 36.5 2.2 15.0 42.6 17.5 1234.9 32.8 6.4 4.6 68.8 10.7 31.8 55.0 76.1 24.8 22.2 466.4 4.3 12.9 15.3 94.5 21.6 24.1 25.2 56.9 30.9 37.3 34.3 25.2 41.2 31.8 28.7 54.8 15.1 11.3 17.2 30.0 3.8 9.1 39.8 15.5 8.5 81.5 46.2 34.9 20.3 176.7 18.2 0.7 11.5 41.8 5.5 33.8 0.1 44.0 6.9 43.0 50.6 26.6 52.6 22.1 103.9 12.0 28.6 10.7 75.4 103.1 22.3 81.4 38.1 19.5 8.4 58.5 1.9 14.3 32.0 16.1 65.3 48.1 12.2 34.6 35.6 1.9 11.6 119.0 24.8 19.5 32.2 46.1 40.7 3.7 2.5 15.3 18.8 3.4 27.3 22.0 26.3 23.8 11.2 32.3 40.6 30.8 1.5 18.2 6.1 47.3 15.8 14.9 69.4 74.5 68.6 79.1 67.3 67.1 71.8 68.3 70.4 68.8 76.1 94.5 9.2 0.0 7.2 5.5 18.0 58.9 42.1 57.8 116.7 41.0 60.3 99.9 99.3 127.2 12.9 16.5 56.3 35.7 15.4 0.8 92.0 39.9 5.2 6.5 7.4 9.2 7.2 35.8 7.4 33.6 41.2 30.9 10.2 4.0 4.5 43.3 18.9 718.3 81.7 18.5 10.1 1.5 6.1 29.5 13.3 16.0 83.9 13.9 32.0 3.7 4.7 57.3 10.3 4.0 36.7 13.5 0.1 139.5 12.5 24.1 0.1 417.4 6.1 61.7 32.9 77.8 47.1 4.3 22.6 42.1 42.9 12.0 19.7 31.1 3.3 23.2 GAN "GAN1, GIG, KLHL16" ENSG00000261609 Gigaxonin Q9H2C0 16 81314944-81390809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 24.8" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 130.4;Urothelial cells: 188.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 10.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011825, HPA049473" Approved Supported Microtubules NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" Microtubules "CAB011825: AB_732515, HPA049473: AB_2680782" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (8.23e-2)" "unprognostic (2.51e-2)" "unprognostic (8.37e-2)" "unprognostic (1.43e-1)" "unprognostic (2.42e-4)" "unprognostic (1.90e-1)" "unprognostic (3.86e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-3)" "unprognostic (5.91e-3)" "unprognostic (3.12e-3)" "unprognostic (5.93e-2)" "unprognostic (9.98e-2)" "unprognostic (1.46e-2)" "unprognostic (5.86e-2)" 1.3 0.9 7.3 0.7 5.7 0.7 2.4 6.6 4.7 2.6 1.0 2.3 0.8 1.3 1.1 5.4 1.3 0.6 1.5 6.9 8.8 1.0 1.1 1.7 0.7 9.3 8.6 1.4 1.2 0.8 1.4 0.8 5.5 2.0 1.2 3.2 2.3 0.7 1.5 24.8 1.4 0.9 8.7 0.9 1.8 0.9 8.7 0.9 1.1 1.4 1.3 1.5 4.3 9.2 1.6 2.0 1.5 2.1 1.9 1.0 10.4 1.2 0.7 0.8 0.3 5.1 1.8 2.5 1.4 1.6 0.4 3.1 2.7 1.3 1.8 0.6 1.4 2.2 1.8 4.1 2.0 2.1 2.4 1.1 3.8 1.3 3.5 1.1 1.7 2.1 2.8 1.1 1.1 9.1 1.9 2.9 4.0 2.2 0.6 3.7 1.4 1.0 1.6 5.0 1.5 1.0 4.3 4.2 1.4 3.6 2.9 2.0 2.5 2.3 2.1 0.8 1.9 2.2 2.7 5.8 1.2 2.4 1.7 0.7 0.4 0.2 0.8 0.4 0.7 0.4 0.8 0.6 0.2 0.5 0.7 0.9 0.3 0.9 0.3 0.9 0.6 0.2 7.3 5.7 6.6 4.7 6.9 8.8 9.3 8.6 5.5 8.7 8.7 9.2 12.2 12.8 8.2 69.5 9.9 91.3 66.8 15.0 34.1 28.4 15.4 18.5 12.5 7.2 29.5 5.5 89.6 19.3 17.4 27.5 0.0 9.4 2.3 11.6 19.3 14.7 5.4 12.6 21.2 6.7 15.4 14.1 17.3 14.0 1.3 7.2 12.1 6.7 5.6 23.5 29.5 15.1 10.2 6.8 30.9 4.6 9.6 8.6 37.4 14.0 7.5 14.0 9.2 22.1 18.3 18.6 16.8 12.8 11.0 75.0 14.8 3.8 30.1 43.8 6.6 20.2 17.6 11.9 16.4 67.1 130.4 21.3 16.1 5.3 15.6 188.7 GAPT "C5orf29, FLJ33641" ENSG00000175857 "GRB2 binding adaptor protein, transmembrane" Q8N292 5 58491435-58497090 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 16.9;lymphoid tissue: 42.7" "Cell type enhanced" "Detected in some" "B-cells: 84.8;dendritic cells: 160.1;granulocytes: 55.0;Macrophages: 43.0;monocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 1000.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 1000.3" "Cell line enhanced" "Detected in some" "HEL: 71.5;HL-60: 41.8;NB-4: 43.3;THP-1: 33.7;U-937: 118.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011048, HPA011070" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA011048: , HPA011070: AB_1848887" "unprognostic (9.79e-2)" "unprognostic (5.67e-3)" "unprognostic (2.39e-2)" "unprognostic (3.26e-2)" "unprognostic (3.36e-2)" "unprognostic (8.09e-4)" "unprognostic (4.32e-1)" "unprognostic (1.23e-3)" "unprognostic (4.14e-2)" "unprognostic (9.47e-3)" "unprognostic (7.28e-2)" "unprognostic (2.93e-1)" "unprognostic (3.52e-3)" "unprognostic (3.74e-2)" "unprognostic (2.42e-2)" "unprognostic (2.33e-2)" "unprognostic (1.40e-2)" 1.7 0.8 0.7 28.5 0.7 16.9 2.3 0.7 1.1 2.7 1.3 2.7 3.7 1.3 1.1 2.1 1.6 5.7 0.7 0.7 1.0 0.8 2.0 4.2 25.3 1.3 1.1 0.4 1.1 1.1 0.6 1.0 1.3 1.8 3.8 0.5 1.9 1.2 0.2 0.8 6.6 4.7 1.0 18.2 3.7 0.7 1.1 6.9 0.6 0.7 42.7 6.0 0.5 1.8 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 71.5 0.2 0.0 0.0 41.8 12.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 43.3 0.0 0.0 0.0 17.7 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 33.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 118.4 0.0 125.5 66.7 1000.3 0.4 46.5 0.5 97.0 0.4 0.4 76.8 97.4 0.3 0.3 82.0 1.4 59.3 205.4 0.3 32.0 0.7 0.7 0.7 1.1 0.7 1.0 1.3 1.1 1.3 1.0 1.1 1.8 0.4 3.2 1.9 0.0 84.8 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.2 0.0 0.6 0.0 0.0 0.0 160.1 0.0 0.0 0.0 1.6 0.0 0.1 0.9 0.0 8.8 0.0 0.0 0.1 0.4 0.5 0.0 55.0 0.0 0.4 0.0 14.3 0.0 0.0 0.0 0.0 19.4 6.0 0.5 0.0 43.0 0.0 1.9 41.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 GAS2L3 ENSG00000139354 "Growth arrest specific 2 like 3" Q86XJ1 12 100573683-100628288 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 4 "spinal cord: 13.8" HPA048593 Approved NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA048593: AB_2680455" "unprognostic (1.03e-1)" "unprognostic (5.13e-2)" "unprognostic (5.10e-2)" "unprognostic (2.70e-2)" "unprognostic (2.32e-2)" "unprognostic (1.46e-1)" "unprognostic (1.04e-7)" "unprognostic (2.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (9.21e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.58e-7)" "unprognostic (1.34e-1)" "unprognostic (2.35e-1)" "unprognostic (3.60e-2)" "unprognostic (6.67e-2)" 1.8 0.8 0.1 1.6 1.4 5.6 0.8 0.1 0.7 1.2 0.5 3.3 2.7 0.7 0.4 1.6 0.3 4.8 1.5 0.5 0.1 1.3 1.0 2.5 1.3 0.5 0.5 1.1 0.5 0.2 0.2 3.5 0.5 0.3 3.8 0.4 0.5 1.1 0.8 3.4 2.7 1.6 0.3 1.4 1.4 4.0 1.4 0.9 0.6 1.2 1.2 1.6 0.5 1.1 35.4 14.0 18.6 14.8 5.7 7.3 6.2 16.2 15.3 21.3 23.8 10.4 9.5 0.6 4.8 12.8 20.8 11.8 12.0 5.9 31.0 10.0 9.1 0.0 12.2 7.0 1.9 0.0 8.0 2.9 0.6 12.8 36.1 10.1 20.2 0.0 2.2 0.0 17.7 10.4 0.0 0.2 5.9 6.5 16.7 2.4 32.5 0.8 9.2 9.6 8.4 8.1 17.0 11.7 22.2 6.5 21.3 1.9 13.6 13.6 14.3 12.2 17.8 7.4 9.3 0.0 5.3 5.6 39.3 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.1 0.1 1.4 0.1 0.7 0.5 0.1 0.5 0.5 0.5 0.3 1.4 1.1 3.6 0.0 0.0 1.0 0.2 3.4 0.4 0.5 2.8 0.2 2.0 2.2 2.0 11.5 0.2 0.0 0.0 9.9 0.4 9.8 0.0 2.7 4.5 3.6 5.5 5.6 3.6 6.9 2.5 0.7 4.5 2.2 11.2 7.4 1.3 7.2 2.5 1.4 13.9 0.0 5.9 14.2 0.0 8.0 11.1 0.5 0.6 14.7 7.2 4.7 1.5 2.2 0.0 2.5 0.3 0.3 8.2 0.7 0.3 0.6 2.6 3.4 1.0 0.1 0.0 4.8 2.7 16.0 2.3 4.7 3.7 33.9 1.0 6.8 8.3 0.6 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GATA3 HDR ENSG00000107485 "GATA binding protein 3" P23771 10 8045378-8075198 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 109.9;skin 1: 172.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 267.1;Cytotrophoblasts: 323.5;Extravillous trophoblasts: 746.6;Suprabasal keratinocytes: 198.9;Syncytiotrophoblasts: 1134.9" "Group enriched" "Detected in many" 24 "breast cancer: 190.0;urothelial cancer: 87.0" "Group enriched" "Detected in many" 5 "midbrain: 28.3;pons: 12.6" "Group enriched" "Detected in many" 41 "gdT-cell: 19.9;MAIT T-cell: 26.9;memory CD4 T-cell: 36.7;memory CD8 T-cell: 28.8;naive CD4 T-cell: 19.9;naive CD8 T-cell: 18.3;NK-cell: 36.1;T-reg: 43.6" "Group enriched" "Detected in many" 57 "NK-cells: 36.1;T-cells: 43.6" "Cell line enhanced" "Detected in many" "BEWO: 190.2;MCF7: 473.4;RT4: 194.3;SH-SY5Y: 161.2;T-47d: 605.2" "Region enriched" "Detected in single" 6 "midbrain: 6.1" "Group enriched" "Detected in some" 11 "medulla oblongata: 5.2;midbrain: 14.0;pons: 11.8;thalamus: 13.1" "CAB016217, HPA029730" Enhanced Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB016217: AB_2108591, HPA029730: AB_10601907" "unprognostic (1.70e-1)" "unprognostic (7.23e-2)" "unprognostic (3.58e-2)" "unprognostic (2.00e-1)" "unprognostic (7.03e-3)" "unprognostic (4.68e-3)" "unprognostic (4.23e-2)" "unprognostic (9.65e-2)" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (3.83e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (6.31e-2)" "unprognostic (1.82e-3)" 6.7 6.4 0.9 3.8 0.2 4.1 34.2 0.2 0.2 3.4 0.8 0.7 1.0 0.6 8.6 0.6 0.5 1.2 2.5 0.1 0.6 24.9 1.0 3.4 7.8 3.9 28.3 0.1 0.3 109.9 5.0 32.2 12.6 11.2 0.7 0.0 19.9 24.9 2.1 172.9 2.4 0.3 0.5 7.2 1.5 0.2 4.1 25.0 3.0 1.0 3.8 38.8 10.8 0.2 33.8 8.1 0.0 0.4 0.0 0.0 190.2 0.7 0.0 0.0 0.1 12.4 29.9 0.0 0.1 0.0 0.0 28.9 3.2 0.6 0.1 95.8 10.2 0.2 0.3 0.1 2.1 0.1 0.5 0.0 6.9 0.1 1.8 1.0 15.3 45.8 0.4 0.0 0.1 473.4 54.2 0.5 3.5 6.5 4.5 2.8 2.6 0.8 0.0 194.3 9.8 161.2 0.5 26.8 0.0 34.1 605.2 0.1 0.0 2.4 5.9 1.4 4.3 0.9 0.0 0.0 1.3 0.0 1.7 0.1 0.1 0.0 19.9 0.0 26.9 0.4 36.7 28.8 0.0 0.1 19.9 18.3 0.7 36.1 0.0 0.0 43.6 7.0 0.9 0.2 0.2 0.2 0.1 0.6 3.9 28.3 12.6 0.5 4.1 0.2 14.6 0.0 6.0 0.0 3.4 94.8 69.6 1.6 0.0 0.0 267.1 167.3 1.3 0.0 1.5 178.4 0.0 323.5 49.2 0.0 0.0 0.2 0.2 0.5 0.4 12.6 0.0 2.1 0.0 0.4 746.6 5.3 2.6 0.7 2.5 0.0 6.8 0.6 30.7 0.0 0.0 0.0 0.0 3.5 9.9 0.1 0.0 3.8 8.8 1.0 1.5 0.0 51.5 0.0 0.0 4.1 1.1 0.0 12.2 45.8 0.0 0.6 0.3 0.0 0.0 1.1 2.8 0.0 1.4 1.0 198.9 1134.9 93.4 0.5 0.0 106.1 GATAD2A p66alpha ENSG00000167491 "GATA zinc finger domain containing 2A" Q86YP4 19 19385826-19508931 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006759, HPA024373" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA006759: AB_1079549, HPA024373: AB_1849522" "unprognostic (1.07e-1)" "unprognostic (2.79e-2)" "unprognostic (1.40e-1)" "unprognostic (5.64e-3)" "unprognostic (3.41e-1)" "unprognostic (1.86e-1)" "unprognostic (9.04e-3)" "unprognostic (9.53e-2)" "unprognostic (2.12e-1)" "unprognostic (2.58e-2)" "unprognostic (6.62e-3)" "unprognostic (4.69e-2)" "unprognostic (3.06e-3)" "unprognostic (4.50e-2)" "unprognostic (2.43e-1)" "unprognostic (3.30e-2)" "unprognostic (9.84e-2)" 16.7 15.1 13.1 23.6 14.0 32.6 15.4 11.0 12.6 13.6 17.1 19.5 22.8 14.8 8.7 22.0 12.3 14.4 12.3 16.7 13.5 16.1 17.1 21.7 19.8 17.6 14.4 11.4 21.6 15.1 14.9 17.8 14.3 10.7 11.3 8.4 15.5 11.0 17.9 30.0 24.8 8.3 14.4 22.2 17.8 33.0 14.8 19.5 14.7 6.9 13.6 15.1 16.4 12.7 60.7 50.8 46.5 69.3 18.9 19.7 97.5 46.7 31.6 47.7 45.4 92.8 62.6 117.9 69.5 47.1 31.6 49.6 43.6 41.5 27.6 40.6 47.7 87.1 49.4 51.8 46.2 97.6 72.1 31.3 30.2 49.9 40.0 15.8 48.2 66.9 141.1 37.1 28.1 68.5 115.9 38.7 98.3 55.8 45.9 121.9 46.6 54.9 24.9 79.0 87.7 48.9 40.4 48.6 57.5 30.2 44.0 40.3 94.9 89.9 43.3 106.8 88.5 46.1 62.9 125.3 56.2 80.9 53.7 4.6 2.9 3.2 3.2 1.5 1.9 2.3 1.9 2.7 1.3 1.5 1.4 1.6 7.8 2.7 3.3 3.0 1.3 2.3 13.1 14.0 11.0 12.6 16.7 13.5 17.6 14.4 14.3 14.4 14.8 12.7 35.7 12.8 19.2 24.5 24.1 55.7 22.3 14.2 26.2 16.1 33.5 21.5 13.5 24.3 15.4 14.7 18.8 23.7 66.3 53.4 13.7 21.9 21.8 43.9 42.8 31.4 15.6 21.0 14.9 30.6 36.8 21.9 29.0 69.5 17.1 22.1 29.3 27.9 27.7 23.5 21.4 28.9 24.4 27.3 42.1 18.5 15.5 27.7 32.0 35.6 28.5 18.2 53.5 17.1 21.6 46.4 28.8 13.9 19.5 24.1 30.2 29.9 15.8 18.3 19.7 40.5 25.8 18.4 41.4 39.5 55.5 36.7 39.3 28.2 32.2 28.2 GATM AGAT ENSG00000171766 "Glycine amidinotransferase" P50440 15 45361124-45402327 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "kidney: 2099.3;liver: 2804.2;pancreas: 2935.3" "Group enriched" "Detected in many" 8 "Hepatocytes: 1495.2;Proximal tubular cells: 3703.0" "Cancer enhanced" "Detected in all" "liver cancer: 135.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 11.0;myeloid DC: 6.6;naive B-cell: 5.4;plasmacytoid DC: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 11.0;dendritic cells: 6.8" "Group enriched" "Detected in many" 4 "RH-30: 210.1;RT4: 55.8;U-266/70: 126.3;U-266/84: 165.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026077 Enhanced Supported Mitochondria NA NA 600000 "Cluster 43: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA026077: AB_1849528" "unprognostic (1.91e-1)" "unprognostic (1.33e-2)" "unprognostic (2.77e-2)" "unprognostic (6.57e-2)" "unprognostic (9.43e-2)" "unprognostic (1.67e-2)" "unprognostic (6.99e-3)" "unprognostic (1.04e-1)" "unprognostic (4.51e-2)" "unprognostic (3.36e-2)" "unprognostic (1.33e-1)" "unprognostic (5.67e-2)" "prognostic favorable (1.38e-4)" "unprognostic (1.09e-1)" "unprognostic (4.07e-2)" "unprognostic (3.60e-2)" "unprognostic (1.80e-1)" 14.4 21.4 133.9 12.4 138.4 1.8 25.4 152.5 216.5 9.9 94.3 19.6 175.5 8.4 10.5 25.1 11.6 47.7 57.2 131.1 140.9 2099.3 2804.2 7.3 18.4 148.0 135.4 165.2 2935.3 2.7 8.3 74.7 153.4 12.4 11.5 7.5 57.5 15.1 142.5 137.6 110.2 14.5 149.2 33.6 99.2 78.2 140.4 12.6 63.0 46.9 29.7 18.0 15.5 181.2 12.9 6.5 4.4 0.6 0.1 0.2 0.8 0.1 0.1 0.0 0.2 1.4 21.4 34.4 1.0 0.0 5.7 2.2 17.0 0.6 0.4 1.9 0.3 2.8 0.4 0.3 0.8 20.7 2.6 0.8 0.7 0.0 0.4 0.0 0.3 7.8 0.4 0.7 0.2 0.6 2.2 0.6 11.2 31.3 0.0 0.5 210.1 1.5 3.5 55.8 23.5 4.1 6.9 0.4 1.2 2.1 2.9 23.7 0.0 0.0 0.5 0.2 6.3 126.3 165.5 0.8 1.6 0.3 1.0 0.0 1.1 0.3 0.2 1.6 0.0 11.0 0.0 0.2 6.6 5.4 0.0 1.4 0.0 0.1 0.6 6.8 0.0 1.0 133.9 138.4 152.5 216.5 131.1 140.9 148.0 135.4 153.4 149.2 140.4 181.2 2.4 3.2 1.1 67.3 42.3 54.3 14.9 5.2 5.7 8.1 16.9 9.5 35.5 228.8 5.4 71.7 0.0 1.0 0.8 3.1 295.4 58.2 8.8 1.3 0.4 7.3 0.0 29.3 6.8 290.0 1.2 19.8 69.8 2.7 3.8 219.5 23.9 1495.2 89.6 8.4 3.3 3.1 2.0 80.3 80.3 18.3 4.4 50.6 23.2 20.6 3.1 19.1 2.1 57.3 196.3 97.3 3.9 3.4 7.2 6.4 98.4 3703.0 1.9 3.8 6.6 38.4 16.8 22.0 9.7 16.0 133.7 1.8 17.6 4.1 3.4 20.4 GBP2 ENSG00000162645 "Guanylate binding protein 2" P32456 1 89106132-89150456 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 152.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 19.1;EFO-21: 20.3;HDLM-2: 25.9;HUVEC TERT2: 18.1;RT4: 21.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042682, CAB045975" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "CAB045975: AB_10584474, HPA042682: AB_2678113" "prognostic favorable (7.57e-4)" "unprognostic (2.92e-2)" "unprognostic (3.65e-2)" "unprognostic (3.02e-2)" "unprognostic (1.34e-1)" "unprognostic (4.68e-2)" "unprognostic (2.70e-2)" "unprognostic (1.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.75e-3)" "prognostic unfavorable (5.73e-5)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.14e-10)" "unprognostic (7.75e-2)" "unprognostic (1.65e-1)" "unprognostic (1.29e-2)" "prognostic favorable (1.10e-5)" 66.6 89.2 3.1 31.8 3.2 8.0 64.6 2.8 4.7 80.4 2.5 100.4 15.0 63.4 11.7 41.2 64.4 22.7 21.4 2.5 4.6 27.3 27.7 89.7 26.2 8.8 5.1 60.5 7.5 27.9 13.8 8.1 5.7 54.6 18.4 0.5 34.6 20.6 53.8 55.4 62.0 31.8 3.7 51.1 46.0 9.0 6.4 9.3 21.1 16.5 15.9 83.8 65.4 4.0 5.4 0.1 0.0 0.0 19.1 12.5 1.9 2.1 17.0 2.1 6.8 0.0 5.0 0.0 20.3 14.0 14.8 0.7 0.0 0.1 1.3 25.9 0.0 0.1 3.1 1.3 2.6 0.5 0.9 14.1 0.0 5.1 0.0 9.3 18.1 0.0 0.3 0.4 7.4 0.0 0.0 4.3 0.0 4.6 0.1 0.0 7.5 0.0 3.7 21.6 0.0 0.2 7.4 1.5 0.1 0.5 0.1 1.0 13.9 2.7 0.1 3.1 1.5 14.0 0.0 0.0 6.9 0.1 0.1 19.1 31.4 10.9 34.4 42.8 43.3 4.7 32.4 32.9 11.6 3.4 24.3 25.4 139.4 26.7 77.8 0.6 79.1 32.5 3.1 3.2 2.8 4.7 2.5 4.6 8.8 5.1 5.7 3.7 6.4 4.0 35.4 25.6 34.3 0.7 21.5 46.5 123.5 24.9 18.2 0.2 56.1 30.4 4.1 27.1 27.1 18.4 0.0 40.2 47.7 41.9 0.0 113.9 35.7 59.6 39.7 60.5 10.2 8.2 0.6 73.2 51.2 41.2 18.3 152.4 47.4 2.5 28.2 30.5 33.2 0.0 1.1 15.7 8.2 84.5 29.4 33.3 4.7 81.1 8.8 14.0 60.6 0.5 110.2 1.5 0.1 73.2 25.9 8.6 17.3 80.3 128.3 12.2 27.5 0.2 19.7 81.9 45.2 1.8 4.6 24.9 61.8 57.7 81.8 33.3 15.3 87.0 GBP5 ENSG00000154451 "Guanylate binding protein 5" Q96PP8 1 89258950-89272804 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.9;lymphoid tissue: 73.9" "Cell type enhanced" "Detected in many" "dendritic cells: 39.2;NK-cells: 75.2;Plasma cells: 22.9;T-cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 243.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "EFO-21: 6.5;NB-4: 10.0;U-266/70: 20.7;U-937: 31.5" "Low region specificity" "Detected in many" HPA028656 Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA028656: AB_10601471" "unprognostic (2.72e-2)" "unprognostic (1.82e-2)" "prognostic favorable (9.54e-4)" "prognostic favorable (3.73e-6)" "unprognostic (8.33e-2)" "unprognostic (8.68e-3)" "unprognostic (3.71e-2)" "unprognostic (6.43e-3)" "unprognostic (2.37e-3)" "prognostic favorable (1.24e-4)" "unprognostic (3.47e-2)" "unprognostic (4.16e-1)" "prognostic unfavorable (5.53e-8)" "unprognostic (2.75e-2)" "unprognostic (3.68e-2)" "unprognostic (1.66e-1)" "unprognostic (4.11e-2)" 3.7 3.3 0.4 73.9 0.5 34.9 4.6 0.4 1.7 3.1 1.5 6.9 5.8 2.3 1.4 2.6 3.1 11.5 2.0 0.4 0.5 2.0 11.1 19.1 54.4 2.9 0.7 2.7 1.1 0.7 1.0 2.8 1.2 2.3 8.0 0.2 4.8 1.2 0.7 1.0 9.0 6.1 0.5 42.7 9.2 4.0 0.8 12.4 2.3 0.9 23.3 12.7 1.4 0.7 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.7 1.2 1.2 0.0 0.1 0.1 6.5 5.3 2.6 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.9 0.6 3.0 0.3 0.0 0.0 10.0 1.4 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.1 0.6 1.3 0.1 0.0 0.0 4.0 0.1 0.5 0.5 0.0 2.2 20.7 0.5 0.1 0.2 31.5 0.0 0.9 15.3 1.1 97.5 38.0 150.4 4.8 63.1 89.3 6.7 6.0 23.2 35.8 97.9 53.4 44.9 0.7 243.8 38.4 0.4 0.5 0.4 1.7 0.4 0.5 2.9 0.7 1.2 0.5 0.8 0.7 2.1 6.4 5.1 0.0 12.4 0.0 0.2 0.5 0.6 0.0 0.4 0.4 0.7 1.5 4.2 0.0 4.2 0.1 39.2 0.1 0.0 0.0 0.4 3.7 0.4 2.8 0.0 0.8 0.0 1.1 0.0 1.5 2.0 3.9 10.8 0.2 4.6 0.6 4.0 0.0 0.7 0.0 0.0 18.9 1.4 0.2 0.0 17.1 0.0 2.8 10.4 2.9 75.2 0.0 0.0 1.3 0.0 0.0 22.9 0.4 0.0 0.3 8.0 0.4 0.0 0.9 0.9 0.1 2.9 0.9 0.0 0.1 72.9 11.0 0.1 0.1 GCLM GLCLR ENSG00000023909 "Glutamate-cysteine ligase modifier subunit" P48507 1 93885199-93909456 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 48.5" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 207.9;Erythroid cells: 301.9;Prostatic glandular cells: 762.3;Urothelial cells: 374.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009568, HPA023696, CAB040554" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1100000 "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009568: AB_2107835, CAB040554: , HPA023696: AB_1849560" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (8.85e-3)" "unprognostic (1.56e-2)" "unprognostic (2.83e-2)" "unprognostic (4.64e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.37e-1)" "unprognostic (1.07e-1)" "unprognostic (3.53e-1)" "unprognostic (3.51e-2)" "unprognostic (3.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (2.34e-3)" 12.2 13.1 5.4 6.6 4.7 15.0 6.6 5.1 5.4 4.5 5.6 6.2 19.2 3.6 4.0 6.6 14.3 14.1 4.7 4.7 7.5 11.3 48.5 5.9 4.6 6.4 6.9 2.8 7.7 6.7 3.4 10.3 7.1 5.6 5.5 3.6 4.5 5.9 16.0 3.0 12.7 3.6 5.1 6.8 5.7 3.2 5.7 5.0 16.8 11.8 10.1 6.9 3.7 6.1 37.7 58.6 6.4 12.6 20.9 13.0 24.4 43.7 27.3 32.8 24.3 9.9 21.7 14.2 84.8 28.8 106.7 37.3 9.6 18.0 26.2 38.6 12.7 98.9 37.4 42.8 39.1 36.8 15.2 16.1 6.7 67.0 10.7 13.2 36.4 16.0 40.0 20.5 24.0 7.3 26.8 8.5 21.5 36.0 27.4 12.3 19.0 20.9 23.6 43.4 14.8 6.1 41.3 32.2 15.4 71.8 7.2 22.7 38.4 34.1 20.1 64.5 66.7 18.1 25.0 14.7 28.2 20.4 12.2 2.1 0.3 0.7 2.6 0.2 1.5 1.3 2.5 3.4 0.3 2.0 1.5 1.6 1.5 2.3 0.3 1.0 0.7 0.7 5.4 4.7 5.1 5.4 4.7 7.5 6.4 6.9 7.1 5.1 5.7 6.1 28.7 41.7 19.1 16.0 14.6 11.5 207.9 33.2 24.5 24.8 24.2 34.2 16.4 61.5 29.0 29.5 6.2 63.5 39.3 21.7 25.4 25.1 3.9 66.3 27.6 55.5 52.5 301.9 32.0 12.3 19.6 44.5 15.8 50.1 19.7 17.3 31.4 102.4 19.9 33.7 30.7 19.9 22.4 20.7 51.4 4.0 21.5 32.0 8.8 15.0 9.3 21.2 34.0 11.1 11.6 24.2 8.0 12.4 21.6 762.3 47.2 65.1 64.3 13.1 0.0 48.4 37.1 32.0 36.7 33.5 9.2 45.0 34.1 26.5 17.8 374.9 GCSAML "C1orf150, FLJ44728" ENSG00000169224 "Germinal center associated signaling and motility like" Q5JQS6 1 247507058-247577690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4;prostate: 5.5" "Cell type enriched" "Detected in some" 24 "granulocytes: 223.3" "Cancer enriched" "Detected in single" 13 "prostate cancer: 1.9" "Region enriched" "Detected in some" 5 "cerebellum: 6.4" "Immune cell enriched" "Detected in single" 661 "basophil: 227.7" "Lineage enriched" "Detected in single" 661 "granulocytes: 227.7" "Group enriched" "Detected in some" 71 "HEL: 151.8;HMC-1: 564.8" "Low region specificity" "Detected in all" "HPA027507, HPA027510" Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA027507: AB_10600756, HPA027510: AB_2672309" "unprognostic (5.68e-2)" "unprognostic (1.86e-1)" "unprognostic (4.07e-3)" "unprognostic (3.48e-2)" "unprognostic (1.72e-1)" "unprognostic (2.76e-4)" "unprognostic (3.21e-1)" "unprognostic (6.14e-2)" "unprognostic (5.42e-2)" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.81e-1)" "unprognostic (9.51e-3)" "unprognostic (3.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.24e-1)" "unprognostic (1.40e-2)" 0.5 0.2 0.4 0.8 0.4 1.8 1.0 6.4 0.7 0.7 0.4 1.2 1.5 0.8 0.5 1.1 0.3 1.4 0.2 0.3 0.4 0.1 0.2 2.1 0.3 0.4 0.3 0.1 0.4 0.1 0.0 0.3 1.2 5.5 1.5 1.2 0.3 0.4 0.2 0.7 1.4 0.6 0.1 0.4 0.9 3.4 0.4 0.7 0.3 0.7 0.2 0.7 0.3 1.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.8 0.8 0.2 0.1 0.0 0.1 151.8 0.2 0.0 0.0 0.3 564.8 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.0 0.1 0.3 0.3 5.0 0.2 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.4 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.4 0.0 0.0 0.3 0.2 0.0 2.3 0.1 0.4 227.7 0.1 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.3 0.3 0.2 0.2 0.2 0.2 0.1 0.2 0.5 0.4 0.4 6.4 0.7 0.3 0.4 0.4 0.3 1.2 0.1 0.4 1.2 0.0 0.0 4.4 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 1.9 0.0 9.1 0.0 0.1 0.6 0.0 5.0 0.4 0.0 0.0 0.3 0.0 0.0 223.3 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.7 7.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 8.3 1.7 0.0 0.6 0.0 1.4 0.1 0.0 0.2 GDF7 BMP12 ENSG00000143869 "Growth differentiation factor 7" Q7Z4P5 2 20667144-20679243 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 9.8;seminal vesicle: 22.4" "Group enriched" "Detected in some" 12 "Endometrial stromal cells: 137.0;Granulosa cells: 83.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.7;Hep G2: 4.4;RT4: 8.3;SH-SY5Y: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA069106 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA069106: " "unprognostic (1.35e-1)" "unprognostic (9.93e-3)" "unprognostic (5.10e-1)" "unprognostic (2.44e-3)" "unprognostic (1.35e-1)" "unprognostic (2.06e-3)" "unprognostic (8.63e-3)" "unprognostic (6.31e-3)" "unprognostic (8.00e-3)" "unprognostic (3.85e-1)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.28e-3)" "unprognostic (8.02e-3)" "unprognostic (2.05e-1)" "unprognostic (3.44e-2)" "unprognostic (1.89e-3)" 0.4 0.4 0.2 1.0 0.5 0.2 0.1 0.0 2.5 9.8 0.0 0.5 0.2 7.2 3.3 0.9 0.7 0.6 0.8 0.4 0.1 3.6 5.0 0.4 2.3 0.3 0.1 0.3 0.6 0.1 0.3 0.8 0.0 3.8 0.2 0.1 0.1 22.4 0.0 1.3 1.6 1.1 0.0 1.3 0.7 0.2 0.3 0.2 0.2 0.6 1.8 1.1 6.6 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 1.2 8.3 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.5 0.4 0.1 0.3 0.1 0.0 0.0 0.3 0.6 0.1 6.4 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.5 0.0 0.0 8.8 2.8 3.1 5.5 0.0 0.0 0.1 0.1 1.9 0.1 0.1 3.5 137.0 1.8 0.0 2.7 0.2 0.0 0.1 1.3 0.0 2.9 0.0 83.7 0.0 8.2 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 4.1 0.7 0.0 0.0 0.3 7.1 0.5 1.0 0.0 0.0 0.0 0.8 0.0 0.0 1.5 GDPD2 "FLJ20207, GDE3, OBDPF" ENSG00000130055 "Glycerophosphodiester phosphodiesterase domain containing 2" Q9HCC8 X 70423031-70433390 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 20.8;lymphoid tissue: 59.2;skin 1: 47.8" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 56.7;Distal enterocytes: 30.4;Muller glia cells: 29.9;Proximal enterocytes: 92.2" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 9.2;NTERA-2: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 45: Enterocytes - Digestion" "unprognostic (1.53e-3)" "unprognostic (5.79e-2)" "unprognostic (5.37e-2)" "unprognostic (5.00e-7)" "unprognostic (3.15e-3)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" "unprognostic (8.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.41e-2)" "unprognostic (5.52e-2)" "unprognostic (2.22e-1)" "unprognostic (8.91e-2)" 0.0 0.0 10.4 0.5 9.8 0.1 0.9 7.6 10.3 0.0 8.9 4.8 11.1 0.0 4.9 0.2 0.2 0.2 0.7 8.5 11.0 0.5 0.0 0.0 0.0 9.4 14.4 0.1 0.0 0.0 3.2 0.1 10.4 0.0 3.9 3.6 1.0 0.3 0.5 47.8 20.8 0.1 9.0 59.2 1.8 0.0 12.4 0.0 0.0 0.0 0.0 0.7 0.1 10.8 0.0 0.0 9.2 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 19.8 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 9.8 7.6 10.3 8.5 11.0 9.4 14.4 10.4 9.0 12.4 10.8 0.0 0.0 0.0 12.7 0.0 56.7 0.0 0.6 0.0 0.2 0.0 0.0 1.9 0.0 0.2 0.0 0.0 7.0 0.0 30.4 0.0 0.0 0.0 0.3 0.0 0.2 1.2 0.0 0.0 0.0 3.5 0.2 3.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 3.7 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.0 92.2 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 12.1 3.3 0.2 0.0 3.1 0.2 GFUS "FX, P35B, SDR4E1, TSTA3" ENSG00000104522 "GDP-L-fucose synthase" Q13630 8 143612618-143618048 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 32.1;Cytotrophoblasts: 82.1;Extravillous trophoblasts: 156.4;Hofbauer cells: 69.9;Syncytiotrophoblasts: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023361 Approved Approved Nucleoplasm,Cytosol Yes No 850000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA023361: AB_1858420" "unprognostic (1.37e-2)" "unprognostic (5.35e-2)" "unprognostic (8.62e-3)" "unprognostic (3.55e-2)" "unprognostic (2.90e-1)" "unprognostic (5.82e-2)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (8.62e-2)" "prognostic favorable (2.41e-4)" "unprognostic (6.62e-3)" "unprognostic (6.89e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (4.23e-2)" "unprognostic (2.78e-2)" "unprognostic (1.87e-2)" "unprognostic (3.27e-2)" 36.3 37.2 21.6 27.7 21.1 52.3 34.0 21.4 25.9 28.6 21.7 45.9 69.2 24.8 19.2 88.7 24.0 29.3 32.1 20.7 21.3 37.5 86.6 28.4 29.1 23.5 21.9 19.0 99.5 22.8 44.0 24.4 22.8 45.0 37.6 6.5 70.9 24.2 30.2 81.5 52.4 19.4 20.2 35.7 111.4 49.4 21.0 26.6 32.1 18.4 27.1 31.0 36.0 22.5 85.6 67.1 29.2 99.7 28.6 26.1 54.1 70.3 73.0 50.2 38.1 78.5 94.3 37.5 64.6 52.5 21.2 60.6 47.8 100.8 23.2 101.7 53.8 58.7 103.0 93.4 57.2 42.2 67.1 30.3 47.4 31.7 127.3 42.2 84.3 61.9 66.4 57.0 41.2 267.5 39.8 53.2 45.8 267.7 87.1 47.1 26.3 122.3 106.1 94.8 67.3 45.9 53.3 100.2 73.0 23.0 133.5 58.8 75.5 34.8 132.0 35.1 67.6 34.1 30.2 29.0 52.8 91.6 54.7 34.9 27.4 42.9 40.3 38.5 43.0 35.2 43.1 46.8 30.1 40.1 31.5 38.5 31.0 63.6 33.8 54.5 57.5 45.7 21.6 21.1 21.4 25.9 20.7 21.3 23.5 21.9 22.8 20.2 21.0 22.5 32.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 82.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 156.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 69.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 87.7 1.7 0.0 0.0 0.0 GGT2 GGT ENSG00000133475 "Gamma-glutamyltransferase 2" P36268 22 21207973-21227637 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 8.7;thyroid gland: 8.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 7.2;Early spermatids: 5.6;Late spermatids: 18.7;Proximal tubular cells: 3.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.6;HeLa: 3.5;Karpas-707: 1.3;U-2197: 8.9" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (4.27e-1)" "unprognostic (6.91e-2)" "unprognostic (7.03e-2)" "unprognostic (8.13e-2)" "unprognostic (1.01e-2)" "unprognostic (2.38e-5)" "unprognostic (1.05e-3)" "unprognostic (5.85e-4)" "unprognostic (7.97e-3)" "unprognostic (8.84e-2)" "unprognostic (1.16e-1)" "unprognostic (6.39e-2)" "unprognostic (2.39e-1)" "unprognostic (1.48e-2)" "unprognostic (3.46e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.7 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 1.5 0.0 0.0 0.5 0.4 0.0 0.1 0.0 0.2 1.0 0.1 0.0 8.5 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 1.6 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.3 0.3 8.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.0 3.2 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GID4 "C17orf39, VID24" ENSG00000141034 "GID complex subunit 4 homolog" Q8IVV7 17 18039408-18068405 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 69.1" "Group enriched" "Detected in many" 12 "Early spermatids: 665.5;Late spermatids: 1287.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 64.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044348 Uncertain Approved Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA044348: AB_10959602" "unprognostic (1.52e-1)" "unprognostic (4.19e-2)" "unprognostic (4.65e-1)" "unprognostic (4.67e-2)" "unprognostic (1.46e-1)" "unprognostic (1.38e-1)" "unprognostic (3.62e-1)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (8.99e-2)" "unprognostic (2.39e-2)" "unprognostic (1.28e-1)" "unprognostic (3.64e-3)" "unprognostic (2.11e-1)" "unprognostic (8.68e-2)" "unprognostic (3.58e-2)" "unprognostic (4.76e-3)" 7.6 5.1 8.3 4.7 7.7 5.8 6.0 9.6 8.6 6.7 5.0 10.0 4.2 7.3 6.5 11.6 6.1 5.1 10.1 7.5 6.6 5.9 5.5 5.3 5.5 7.7 7.6 7.8 7.6 10.5 3.0 6.5 7.7 6.7 4.6 5.7 7.9 7.9 27.7 12.4 4.6 8.5 7.0 5.7 5.8 69.1 7.8 7.2 6.7 14.4 6.0 8.8 7.3 7.7 11.8 12.1 6.7 10.9 17.2 16.8 11.4 9.6 15.6 10.5 11.8 10.2 4.5 14.9 8.1 11.3 9.6 13.1 9.8 10.6 13.7 8.1 19.6 6.6 9.5 7.5 14.9 3.9 11.1 12.5 18.6 10.5 16.3 13.9 11.8 20.9 6.0 4.1 8.6 3.0 12.8 8.4 5.9 14.4 8.8 10.8 23.9 14.8 7.2 4.6 5.0 7.6 6.5 5.7 7.2 64.9 3.6 5.0 10.0 6.7 3.8 15.7 4.9 7.3 6.7 3.2 9.6 6.7 8.8 4.3 1.1 3.6 1.2 0.6 1.3 2.6 1.1 1.2 0.9 2.0 1.3 1.4 2.9 2.0 0.8 1.6 1.9 0.6 8.3 7.7 9.6 8.6 7.5 6.6 7.7 7.6 7.7 7.0 7.8 7.7 8.7 0.0 1.1 5.2 6.0 11.1 7.5 4.5 4.6 5.8 6.4 7.0 12.4 5.7 3.1 1.8 4.2 8.3 6.1 4.1 9.8 5.3 665.5 5.4 9.5 8.4 1.2 17.2 8.2 5.7 15.2 8.0 1.1 5.5 5.7 10.7 8.2 6.8 7.3 16.8 8.1 4.9 0.0 9.5 7.7 1287.8 12.8 7.4 7.2 11.2 9.7 5.4 10.3 9.5 9.8 9.1 1.6 15.8 5.0 16.3 6.9 11.4 3.5 3.9 13.1 8.6 9.0 78.1 26.3 7.2 18.2 15.5 5.9 7.0 4.4 8.0 GIMAP1 "HIMAP1, IAN2, IMAP1, IMAP38" ENSG00000213203 "GTPase, IMAP family member 1" Q8WWP7 7 150716606-150724284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.7" "Cell type enhanced" "Detected in many" "Adipocytes: 189.8;Endothelial cells: 109.9;Hepatic stellate cells: 117.8;Kupffer cells: 109.1;monocytes: 74.9;NK-cells: 185.3;T-cells: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 14.7;MOLT-4: 9.2;TIME: 3.9" "Low region specificity" "Detected in many" "HPA044887, HPA053441" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA044887: AB_10960351, HPA053441: AB_2682152" "unprognostic (1.60e-2)" "unprognostic (6.58e-3)" "unprognostic (8.21e-3)" "unprognostic (2.54e-3)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "prognostic favorable (1.09e-4)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.44e-1)" "unprognostic (4.60e-3)" "unprognostic (7.89e-2)" "unprognostic (1.77e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-1)" 9.8 2.5 3.0 11.0 3.0 1.0 7.9 2.9 3.5 3.8 3.0 3.7 3.5 4.6 1.1 2.1 4.4 3.2 9.3 2.8 2.9 3.5 2.4 8.9 19.6 3.5 3.2 1.5 1.4 1.5 1.1 7.1 3.4 2.3 2.2 0.1 2.5 2.0 5.4 2.5 6.9 3.8 3.5 24.7 3.3 0.8 3.6 6.6 5.3 7.1 8.4 3.5 3.0 3.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.7 1.9 0.0 0.0 0.0 0.0 9.2 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 3.0 32.2 0.1 43.8 29.6 51.1 0.3 47.5 54.2 13.5 0.6 68.2 56.2 2.7 42.6 30.6 0.8 34.0 35.0 3.0 3.0 2.9 3.5 2.8 2.9 3.5 3.2 3.4 3.5 3.6 3.2 189.8 3.2 1.5 0.0 5.1 5.5 0.6 0.0 1.2 0.6 1.9 3.6 5.9 2.8 0.6 0.0 0.0 0.3 51.5 0.1 0.0 0.3 0.3 0.4 0.6 109.9 0.0 10.5 0.0 0.4 0.3 3.7 1.5 0.2 8.2 0.2 117.8 2.0 37.9 0.0 0.0 0.0 0.0 109.1 7.6 1.3 1.5 48.0 8.8 0.0 74.9 0.3 185.3 0.0 0.0 0.1 0.1 0.0 7.6 0.7 0.2 0.5 0.0 1.0 0.0 2.5 3.5 0.3 0.5 0.7 3.1 0.4 97.3 1.0 0.0 0.7 GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 195.2;Hepatic stellate cells: 222.0;Kupffer cells: 197.2;Macrophages: 110.0;monocytes: 176.0;NK-cells: 344.0;T-cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 26 "HUVEC TERT2: 326.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" 46.1 18.3 15.0 75.1 15.6 4.2 31.8 16.2 21.2 19.7 16.3 21.2 16.5 23.0 9.6 12.0 18.7 24.6 31.3 14.3 16.0 17.3 29.9 50.8 127.7 19.2 18.0 7.7 6.7 9.6 6.0 48.7 18.0 10.2 22.4 1.5 11.2 13.3 17.5 8.4 25.0 38.3 18.8 115.6 18.0 4.2 16.4 30.5 21.1 48.1 85.1 31.1 11.6 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 326.4 3.4 0.1 0.3 0.0 0.0 0.4 0.2 0.4 0.0 0.0 12.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 370.2 5.2 325.8 390.9 404.2 3.0 408.0 402.8 122.1 1.3 424.3 361.9 339.7 263.4 320.4 5.3 312.1 776.9 15.0 15.6 16.2 21.2 14.3 16.0 19.2 18.0 18.0 18.8 16.4 18.7 182.3 3.2 12.4 0.3 7.3 6.8 0.2 0.0 3.4 0.1 2.2 4.7 9.9 5.7 1.8 11.0 0.0 0.6 82.6 0.0 0.0 0.2 0.6 0.3 0.4 195.2 0.0 9.7 0.5 0.2 0.8 9.0 2.0 0.3 6.3 0.0 222.0 3.7 96.4 0.0 0.1 0.0 0.0 197.2 20.9 1.7 5.0 110.0 10.6 18.7 176.0 0.2 344.0 0.0 0.1 0.1 0.0 0.0 14.7 0.4 0.0 1.9 0.7 0.4 13.1 3.9 7.9 0.0 0.8 1.1 6.1 0.8 186.2 0.8 0.0 0.3 GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.1;Basal keratinocytes: 11.1;Endothelial cells: 29.7;Langerhans cells: 13.9;Suprabasal keratinocytes: 10.7;T-cells: 31.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "MOLT-4: 41.7" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.77e-2)" "unprognostic (8.83e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-3)" "unprognostic (6.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.13e-1)" "unprognostic (7.15e-3)" "unprognostic (1.86e-1)" "unprognostic (1.47e-2)" 34.4 13.6 13.3 44.8 14.2 5.2 25.5 13.7 16.8 15.9 12.7 16.6 10.6 17.1 8.8 12.4 18.9 17.9 24.2 12.8 13.2 12.7 23.3 39.7 106.2 15.2 14.1 5.9 8.7 9.1 4.1 26.4 14.8 6.6 16.5 0.8 7.2 9.0 12.4 7.2 22.1 30.5 14.2 64.2 15.6 3.5 14.7 25.1 18.3 43.9 66.4 26.7 6.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.3 0.0 1.4 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.4 0.0 3.6 70.5 1.1 260.4 106.3 337.2 1.1 436.3 334.0 8.0 0.6 521.5 280.6 8.3 188.3 43.6 1.6 176.9 510.2 13.3 14.2 13.7 16.8 12.8 13.2 15.2 14.1 14.8 14.2 14.7 13.8 22.1 0.0 1.7 0.0 1.4 11.1 0.3 0.0 1.2 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.1 5.8 0.2 0.0 0.0 0.1 0.0 0.1 29.7 0.0 0.4 0.0 0.0 0.4 2.6 0.5 0.1 2.5 0.0 8.9 0.6 3.1 0.0 0.0 0.2 0.0 5.3 13.9 0.1 0.0 7.1 3.6 0.0 2.2 0.0 9.2 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.1 0.1 0.0 0.1 0.0 0.7 3.2 0.2 0.1 0.1 10.7 0.3 31.5 0.1 0.1 0.1 GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 265.8;Endothelial cells: 263.3;Hepatic stellate cells: 267.4;Kupffer cells: 156.8;monocytes: 140.8;NK-cells: 632.4;T-cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 92.9;MOLT-4: 78.6" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" 49.8 15.0 16.3 73.6 17.4 6.6 37.4 17.1 21.3 19.2 16.0 20.3 21.1 27.8 19.8 12.6 21.5 22.1 40.1 15.5 17.2 20.9 20.4 61.0 170.1 19.0 17.8 7.4 7.6 10.5 5.6 31.5 19.1 10.9 23.3 1.2 13.7 12.0 27.8 9.3 40.1 33.6 17.6 124.3 22.0 4.5 18.0 52.5 28.2 56.1 99.2 29.6 13.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 92.9 9.4 0.0 0.0 0.0 0.0 78.6 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.7 656.5 9.6 1184.0 595.9 1164.2 6.5 1762.9 1440.6 286.3 6.5 2269.3 1597.2 52.5 1121.0 666.6 16.3 1076.9 2581.7 16.3 17.4 17.1 21.3 15.5 17.2 19.0 17.8 19.1 17.6 18.0 17.6 265.8 0.0 13.2 0.3 13.1 2.4 0.4 0.0 2.8 0.0 2.8 5.6 14.6 5.7 0.6 1.8 0.0 0.2 125.1 0.2 0.0 0.5 1.3 0.9 0.6 263.3 0.0 17.0 0.0 0.7 0.0 8.0 3.1 0.7 13.9 0.0 267.4 5.3 15.5 0.0 0.0 0.1 0.0 156.8 10.6 2.0 2.5 54.9 1.8 22.5 140.8 0.4 632.4 0.5 0.1 0.4 1.2 0.4 19.3 0.2 0.0 1.7 0.7 0.4 0.0 6.0 9.4 0.2 0.9 1.1 3.3 0.4 255.9 0.9 0.2 0.0 GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.6" "Cell type enhanced" "Detected in many" "Adipocytes: 67.4;Endothelial cells: 66.0;Hepatic stellate cells: 86.0;Kupffer cells: 75.1;Microglial cells: 32.8;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 59.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA014474: AB_1849685, HPA017765: AB_1849683" "unprognostic (7.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.04e-1)" "unprognostic (4.42e-3)" "unprognostic (2.11e-1)" "unprognostic (8.09e-3)" "unprognostic (1.07e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (6.26e-3)" "unprognostic (2.15e-1)" "unprognostic (1.04e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" 20.3 5.7 4.4 21.3 5.0 0.7 16.0 4.7 5.5 9.8 5.5 6.7 6.8 10.4 3.1 4.3 9.0 7.5 17.4 4.1 4.5 8.3 9.4 27.0 23.2 5.4 4.9 3.5 2.8 4.6 2.6 15.4 5.4 4.9 7.2 0.3 4.3 5.3 9.8 4.7 10.5 12.7 5.4 40.6 5.0 2.0 5.1 7.3 11.9 15.1 13.5 8.4 5.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 59.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.7 0.0 9.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.5 45.2 0.0 15.3 59.0 17.4 0.5 14.8 13.9 13.0 0.0 16.7 13.6 4.8 15.5 57.4 0.7 7.7 26.8 4.4 5.0 4.7 5.5 4.1 4.5 5.4 4.9 5.4 5.4 5.1 5.8 67.4 3.2 5.3 0.3 0.8 3.1 0.5 0.0 1.8 0.0 0.4 0.8 5.5 5.7 0.0 1.8 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.2 0.1 66.0 0.0 1.3 0.1 0.0 0.0 2.3 0.5 0.2 3.8 0.0 86.0 1.6 6.8 0.0 0.1 0.0 0.0 75.1 2.8 0.9 0.3 21.9 0.0 32.8 44.2 0.0 19.6 0.0 0.1 0.0 0.0 0.0 2.2 0.9 0.0 0.2 1.5 0.0 0.0 1.5 1.2 0.2 0.4 0.5 1.7 0.1 11.1 0.2 0.0 0.4 GINS1 "KIAA0186, PSF1" ENSG00000101003 "GINS complex subunit 1" Q14691 20 25407673-25452628 "Disease related genes, Predicted intracellular proteins" "DNA replication" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.3;testis: 9.0" "Cell type enhanced" "Detected in many" "Early spermatids: 60.2;Erythroid cells: 14.7;Extravillous trophoblasts: 17.9;Late spermatids: 21.9;Spermatocytes: 14.2;Spermatogonia: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051185 Uncertain Approved Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA051185: AB_2681378" "unprognostic (6.10e-3)" "unprognostic (2.58e-1)" "unprognostic (5.37e-3)" "unprognostic (1.74e-3)" "unprognostic (2.00e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.61e-7)" "unprognostic (5.86e-3)" "unprognostic (1.42e-2)" "unprognostic (1.32e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.44e-1)" "prognostic unfavorable (5.42e-11)" "unprognostic (5.24e-2)" "unprognostic (1.03e-1)" "unprognostic (4.60e-2)" "unprognostic (2.55e-1)" 0.7 0.6 0.9 3.2 0.8 3.4 1.6 1.8 1.0 1.0 0.4 3.2 3.0 1.4 0.7 4.3 0.8 0.8 0.5 0.8 0.5 1.1 1.2 0.5 5.3 0.4 0.5 0.9 0.5 0.6 0.2 2.9 0.6 0.8 3.9 0.8 0.8 0.4 0.5 3.7 2.9 2.0 0.3 1.5 2.0 9.0 0.6 7.3 0.6 0.0 5.9 1.3 1.5 0.9 43.6 38.8 46.5 30.4 2.6 3.5 46.7 18.9 9.1 35.5 37.2 33.7 42.1 53.3 21.0 7.9 26.4 49.0 40.9 34.4 40.7 14.3 14.2 36.7 13.8 41.3 0.9 48.5 16.2 1.7 2.0 33.8 6.9 4.7 19.1 30.1 36.1 33.9 21.2 47.0 75.1 36.0 31.8 30.0 20.0 53.1 53.6 35.7 13.6 28.8 19.4 20.3 19.3 45.3 16.7 26.0 42.9 24.2 8.7 27.7 29.9 18.2 35.1 13.6 41.1 42.0 7.4 46.8 32.0 0.2 0.2 0.1 0.3 0.2 0.1 0.5 0.2 0.1 0.5 0.3 0.1 0.3 0.2 0.4 0.2 0.5 0.8 0.2 0.9 0.8 1.8 1.0 0.8 0.5 0.4 0.5 0.6 0.3 0.6 0.9 0.2 0.0 0.6 1.3 1.5 3.2 1.0 1.5 1.8 1.8 1.1 1.3 0.4 0.0 1.6 1.8 0.0 8.2 0.2 1.9 0.0 1.1 60.2 0.5 1.3 1.1 1.2 14.7 6.4 0.7 17.9 2.0 3.6 1.3 1.3 6.8 0.7 0.7 5.9 0.0 3.7 2.5 0.0 1.6 0.8 21.9 0.6 1.2 0.0 1.0 0.0 1.3 0.0 4.0 1.6 0.4 0.6 1.2 8.9 0.6 0.4 2.1 1.7 0.2 0.0 0.5 1.4 14.2 19.7 5.4 1.4 2.5 0.8 2.0 5.5 0.8 GINS2 "Pfs2, PSF2" ENSG00000131153 "GINS complex subunit 2" Q9Y248 16 85676198-85690073 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 163.5;Spermatogonia: 148.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 271.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA057285 Uncertain Approved Nucleoplasm No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA057285: AB_2683398" "unprognostic (3.22e-2)" "unprognostic (1.13e-3)" "unprognostic (2.04e-3)" "unprognostic (2.09e-1)" "unprognostic (2.64e-1)" "unprognostic (1.30e-1)" "unprognostic (2.45e-3)" "unprognostic (2.58e-2)" "unprognostic (1.67e-2)" "unprognostic (2.52e-3)" "unprognostic (2.19e-2)" "unprognostic (5.82e-3)" "unprognostic (5.70e-3)" "unprognostic (4.54e-2)" "unprognostic (6.30e-2)" "unprognostic (5.44e-3)" "unprognostic (1.60e-1)" 1.0 0.9 3.0 5.4 2.8 14.7 3.7 3.0 3.7 1.7 2.2 6.4 4.6 1.6 1.3 4.7 1.1 0.4 0.6 4.5 2.2 0.7 3.0 0.8 9.0 2.3 2.4 1.4 0.9 2.6 0.8 3.0 2.3 1.5 7.0 11.1 1.3 0.8 2.7 3.2 5.3 1.6 2.3 3.0 2.2 9.6 2.3 10.2 1.8 1.0 11.0 1.4 2.1 2.6 50.7 36.2 69.0 28.9 2.0 6.7 18.3 33.8 13.7 49.8 30.5 48.2 32.9 60.0 18.1 12.0 26.0 38.0 73.7 28.1 47.9 20.8 63.9 29.2 25.7 54.6 0.3 20.6 15.6 1.8 3.4 30.0 11.5 6.1 21.6 47.5 82.4 13.8 28.9 107.1 72.7 77.8 38.8 45.0 27.3 100.7 41.5 33.1 16.4 20.9 94.2 30.0 49.4 10.0 10.0 27.3 100.0 28.2 12.8 32.1 42.5 30.6 39.5 25.6 48.3 271.9 18.7 43.4 37.2 0.7 0.2 1.1 1.0 1.0 0.1 1.0 3.3 2.3 1.3 0.7 1.6 1.1 0.9 3.2 2.8 0.8 8.5 1.7 3.0 2.8 3.0 3.7 4.5 2.2 2.3 2.4 2.3 2.3 2.3 2.6 0.6 3.2 0.0 0.7 8.5 9.2 7.4 9.5 4.0 20.3 13.1 18.5 1.0 0.0 3.8 3.7 2.1 35.3 3.1 11.9 3.9 8.2 9.8 1.5 3.3 2.4 3.0 43.3 0.5 1.5 31.8 7.2 5.6 2.7 1.3 21.6 0.0 2.1 23.8 8.4 0.4 14.9 4.1 1.3 6.6 29.4 1.2 3.3 0.0 0.0 1.1 5.6 0.0 1.0 0.6 2.0 4.5 1.9 43.1 2.6 2.4 0.7 1.7 7.5 19.7 4.2 7.9 163.5 148.4 13.8 3.8 12.7 4.2 2.2 33.6 7.4 GIPC1 "C19orf3, GIPC, GLUT1CBP, Hs.6454, NIP, RGS19IP1, SEMCAP, SYNECTIN, TIP-2" ENSG00000123159 "GIPC PDZ domain containing family member 1" O14908 19 14477760-14496149 "Human disease related genes, Predicted intracellular proteins" "Congenital muscular dystrophy, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 345.8" "Cell type enhanced" "Detected in all" "Distal enterocytes: 501.1;Pancreatic endocrine cells: 296.7;Paneth cells: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043958, HPA061786" Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 11000 "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA043958: AB_10963436, HPA061786: AB_2756319" "unprognostic (2.80e-1)" "unprognostic (1.16e-1)" "unprognostic (8.21e-2)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-1)" "unprognostic (1.18e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (4.82e-2)" "unprognostic (3.53e-2)" "unprognostic (7.72e-2)" "unprognostic (1.04e-2)" "unprognostic (7.17e-3)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" 51.0 54.8 80.0 22.4 91.5 3.3 54.3 88.7 94.4 99.8 64.7 120.2 24.7 53.7 17.6 345.8 48.9 23.4 66.1 74.5 82.1 104.1 58.4 76.3 15.9 89.4 91.4 34.4 43.5 20.8 56.0 28.7 88.1 63.6 41.1 17.9 100.9 31.0 65.1 150.2 45.5 17.5 82.0 37.7 78.7 24.9 91.1 18.6 55.8 23.3 21.0 74.1 140.1 92.3 328.1 148.6 44.7 70.6 40.6 40.7 35.2 119.7 59.8 96.7 87.3 80.3 120.6 4.7 220.3 85.2 64.6 183.8 38.7 100.6 32.6 33.8 69.0 63.9 100.7 79.7 123.7 6.9 75.3 46.7 98.5 58.8 51.3 57.4 66.0 47.2 30.1 54.4 49.9 243.8 21.3 13.3 48.6 182.1 147.8 21.7 37.4 43.7 121.6 281.6 41.8 46.2 67.1 163.2 157.0 23.1 102.5 35.1 115.4 135.7 74.6 191.7 130.1 50.5 70.5 17.3 113.9 51.9 146.2 3.0 0.7 0.1 5.1 1.1 4.7 1.9 5.1 5.1 1.1 0.8 4.2 3.3 0.3 1.5 0.5 3.6 12.0 1.7 80.0 91.5 88.7 94.4 74.5 82.1 89.4 91.4 88.1 82.0 91.1 92.3 30.6 28.9 15.2 22.9 8.3 113.9 77.4 52.1 35.9 69.8 73.6 31.6 14.8 37.1 62.8 82.8 35.5 36.3 19.3 501.1 52.8 167.9 1.1 92.2 30.5 32.4 43.1 1.7 28.8 164.3 77.1 32.6 69.3 76.8 10.2 37.3 23.2 18.0 55.9 75.7 32.2 87.8 42.7 10.8 29.8 2.4 20.5 16.1 58.7 10.3 23.4 73.3 18.6 17.1 71.6 296.7 285.4 25.2 6.8 120.4 36.0 52.7 38.0 46.0 19.7 18.1 44.5 6.4 20.4 107.0 169.8 25.7 22.9 47.7 138.1 199.7 GIPC2 "FLJ20075, SEMCAP-2" ENSG00000137960 "GIPC PDZ domain containing family member 2" Q8TF65 1 77979542-78138444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.0;kidney: 41.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 122.1;Proximal tubular cells: 267.7;Undifferentiated cells: 63.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.1;HaCaT: 6.0;Hep G2: 23.0;HUVEC TERT2: 23.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051212, HPA062684" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA051212: , HPA062684: AB_2684833" "unprognostic (1.72e-2)" "unprognostic (9.37e-2)" "prognostic favorable (5.49e-4)" "unprognostic (1.09e-2)" "unprognostic (1.43e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.35e-1)" "unprognostic (7.63e-2)" "unprognostic (2.22e-1)" "unprognostic (5.91e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.11e-6)" "unprognostic (6.55e-2)" "unprognostic (1.78e-1)" "unprognostic (4.18e-2)" "unprognostic (1.29e-1)" 3.9 23.8 0.5 1.7 0.4 0.3 3.0 0.4 0.5 1.8 0.5 15.6 38.0 2.1 0.9 2.1 3.1 5.5 1.5 0.5 0.4 41.4 18.4 2.7 0.8 0.4 0.4 2.4 18.1 2.3 0.9 3.5 0.4 1.7 14.9 0.1 4.2 0.9 1.1 4.7 38.0 2.8 0.4 27.9 6.0 1.0 0.5 0.4 1.0 1.6 0.8 2.0 1.9 0.4 0.0 0.0 0.0 0.1 2.4 6.1 0.0 1.0 0.0 0.5 1.1 5.1 3.3 1.5 0.1 0.5 0.0 6.0 0.0 0.0 3.2 0.2 0.0 0.8 0.0 23.0 1.2 0.0 0.0 1.0 0.1 3.5 0.1 0.0 23.5 0.0 0.0 0.1 2.9 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.5 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.4 33.6 0.0 1.3 2.0 2.0 12.9 2.4 0.9 4.0 0.4 5.2 1.5 3.2 27.1 2.5 9.2 2.1 6.7 0.0 43.7 33.2 11.8 2.5 13.3 0.9 21.6 3.0 0.4 14.7 33.0 3.1 2.9 8.6 7.2 0.0 5.9 22.9 43.3 13.2 0.0 15.2 34.4 0.0 0.8 1.9 1.2 1.2 2.1 0.0 14.0 1.0 0.0 0.0 4.5 8.9 16.5 39.3 0.0 0.0 0.8 122.1 267.7 11.7 0.5 0.0 1.3 1.3 0.6 2.5 7.9 21.7 1.6 1.3 32.4 63.8 6.0 GIPC3 "C19orf64, DFNB15, DFNB72, DFNB95" ENSG00000179855 "GIPC PDZ domain containing family member 3" Q8TF64 19 3585478-3593541 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 16.7" "Group enriched" "Detected in some" 4 "Adipocytes: 10.4;Endothelial cells: 6.2;Hepatic stellate cells: 12.8;Rod photoreceptor cells: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 19.0;HMC-1: 11.8;THP-1: 23.1;WM-115: 44.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA067765 Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA067765: " "unprognostic (1.77e-1)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (6.99e-2)" "unprognostic (1.22e-1)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (3.67e-3)" "unprognostic (4.76e-2)" "unprognostic (2.97e-1)" "unprognostic (5.06e-3)" "unprognostic (2.26e-2)" "unprognostic (1.51e-3)" "unprognostic (1.96e-2)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (9.06e-2)" 4.6 2.2 1.4 1.0 1.0 0.3 2.8 1.0 1.1 3.0 0.8 1.9 1.2 2.8 2.9 5.2 2.1 2.1 3.9 1.2 1.2 3.6 1.4 3.8 2.4 1.6 1.2 0.7 0.7 2.7 1.0 1.1 1.6 3.5 1.4 16.7 0.7 2.3 1.7 1.1 4.4 8.3 1.4 3.9 2.0 0.3 1.6 3.1 3.0 1.9 1.6 1.1 1.8 1.1 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.1 0.9 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.4 0.0 1.5 0.0 0.2 6.9 19.0 0.0 0.7 0.0 11.8 0.2 0.0 1.1 0.0 0.0 2.1 0.2 3.2 0.0 0.3 0.0 0.0 1.1 0.7 0.0 1.2 0.5 0.0 0.8 0.0 0.0 0.0 0.1 0.5 0.0 4.7 1.1 0.0 23.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 44.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 1.0 1.1 1.2 1.2 1.6 1.2 1.6 1.4 1.6 1.1 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.4 0.1 0.3 2.4 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 12.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.8 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.2 1.1 0.0 0.4 0.1 0.3 0.1 0.3 0.1 0.0 0.1 GJA9 "CX58, CX59, GJA10" ENSG00000131233 "Gap junction protein alpha 9" P57773 1 38874069-38881587 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "GAMG: 1.0" "Low region specificity" "Detected in all" HPA067850 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "HPA067850: AB_2685910" "unprognostic (2.00e-1)" "unprognostic (8.78e-2)" "unprognostic (4.55e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-2)" "unprognostic (1.20e-2)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (2.75e-2)" "unprognostic (1.90e-2)" "unprognostic (2.63e-1)" "unprognostic (4.11e-3)" "unprognostic (2.32e-2)" 0.1 0.1 0.3 0.0 0.4 0.0 0.0 0.2 0.5 0.1 0.0 0.3 0.2 0.0 0.0 0.4 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.0 0.1 1.4 1.7 0.1 0.1 0.0 0.2 0.0 0.7 0.1 0.2 0.4 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.2 0.8 0.5 0.0 0.2 0.0 0.0 0.2 0.3 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.4 0.2 0.5 0.1 0.1 1.4 1.7 0.7 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GJB5 CX31.1 ENSG00000189280 "Gap junction protein beta 5" O95377 1 34755047-34758512 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "esophagus: 101.0;skin 1: 95.1;vagina: 35.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 48.6;Basal prostatic cells: 38.0;Basal respiratory cells: 49.6;Squamous epithelial cells: 63.8;Suprabasal keratinocytes: 83.5;Urothelial cells: 66.2" "Cancer enhanced" "Detected in many" "cervical cancer: 36.7;head and neck cancer: 57.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 29.1;HaCaT: 90.8;HBEC3-KT: 40.7;hTCEpi: 147.4;RT4: 50.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038146 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038146: AB_10697242" "unprognostic (2.62e-1)" "unprognostic (1.63e-1)" "unprognostic (3.48e-1)" "unprognostic (5.71e-2)" "unprognostic (8.26e-2)" "unprognostic (3.12e-1)" "unprognostic (7.89e-2)" "unprognostic (2.76e-2)" "unprognostic (5.35e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.30e-2)" "unprognostic (1.09e-3)" "unprognostic (2.36e-1)" "unprognostic (2.41e-3)" "unprognostic (5.59e-2)" "unprognostic (5.67e-3)" 0.2 0.1 1.0 0.0 1.0 0.0 3.9 0.6 1.3 12.8 0.0 0.1 0.0 0.1 3.4 101.0 0.6 3.4 0.1 1.4 0.3 0.1 0.4 0.3 0.0 0.4 0.4 0.1 1.1 0.0 0.8 0.6 0.5 5.2 0.1 0.0 13.9 3.1 0.3 95.1 0.2 0.0 0.6 0.1 0.1 2.3 0.7 1.4 0.9 0.1 12.6 7.1 35.0 0.9 29.1 0.3 0.1 0.5 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 2.2 0.0 1.2 0.0 0.3 90.8 0.0 40.7 0.0 0.1 0.0 7.0 0.9 0.0 0.0 0.0 0.0 0.1 147.4 0.0 23.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 50.9 0.1 0.0 3.6 1.5 0.0 0.4 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.6 1.3 1.4 0.3 0.4 0.4 0.5 0.6 0.7 0.9 0.0 0.0 1.1 0.3 0.0 48.6 38.0 49.6 12.5 0.0 2.8 1.9 0.5 0.0 17.2 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.1 0.0 4.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 19.5 0.0 0.0 12.4 0.0 0.0 0.0 1.4 0.0 0.0 63.8 83.5 0.4 0.2 0.0 0.3 66.2 GJC3 "CX30.2, GJE1" ENSG00000176402 "Gap junction protein gamma 3" Q8NFK1 7 99923266-99929620 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 8.7;pancreas: 11.1;salivary gland: 11.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 36.3;Breast myoepithelial cells: 26.9;Exocrine glandular cells: 24.0;Pancreatic endocrine cells: 12.8;Prostatic glandular cells: 13.0" "Group enriched" "Detected in many" 5 "breast cancer: 3.8;melanoma: 3.0;prostate cancer: 3.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.3;SK-MEL-30: 2.3;U-2197: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015024 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" "HPA015024: AB_1847132" "unprognostic (9.31e-2)" "unprognostic (6.43e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-2)" "unprognostic (2.54e-1)" "unprognostic (2.88e-2)" "unprognostic (7.68e-2)" "unprognostic (9.14e-2)" "unprognostic (6.71e-2)" "unprognostic (4.78e-2)" "unprognostic (1.20e-1)" "unprognostic (3.88e-3)" "unprognostic (1.14e-1)" "unprognostic (4.17e-1)" "unprognostic (3.49e-1)" "unprognostic (5.81e-3)" 1.6 0.5 0.8 0.1 0.9 0.1 8.7 0.1 1.2 0.3 0.0 0.5 0.4 0.2 0.0 0.2 0.3 0.3 0.4 0.9 0.3 1.0 2.7 0.2 0.2 0.2 0.4 0.4 11.1 0.0 0.4 1.0 0.2 4.6 0.0 1.0 11.7 0.1 0.2 2.6 0.3 0.2 0.0 0.3 1.4 1.7 0.6 0.1 0.3 0.2 0.0 0.3 0.3 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.5 0.6 0.1 0.5 0.2 0.4 1.1 1.3 0.0 0.0 0.4 0.3 0.0 0.4 0.1 0.2 0.1 0.3 2.3 0.5 0.7 0.0 0.3 0.1 0.4 1.8 0.1 0.1 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.9 0.1 1.2 0.9 0.3 0.2 0.4 0.2 0.0 0.6 0.5 1.1 3.2 3.7 0.0 0.4 0.3 4.9 1.4 0.0 0.0 36.3 26.9 0.0 4.3 2.1 1.8 0.0 0.0 0.6 0.0 1.9 0.4 0.4 0.0 0.0 1.5 1.2 0.0 0.7 24.0 0.0 0.2 0.0 0.0 4.5 0.2 1.1 5.0 0.1 0.0 0.4 0.1 8.2 0.0 0.3 1.1 0.3 0.1 0.0 0.0 0.6 4.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 13.0 0.0 9.7 0.3 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 9.4 GK5 MGC40579 ENSG00000175066 "Glycerol kinase 5" Q6ZS86 3 142157527-142225592 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycerol metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 127.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042606, HPA057998" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA042606: AB_10795509, HPA057998: AB_2683573" "unprognostic (7.79e-2)" "unprognostic (5.15e-2)" "unprognostic (2.02e-2)" "unprognostic (1.33e-1)" "unprognostic (3.07e-2)" "unprognostic (3.60e-2)" "unprognostic (9.89e-3)" "unprognostic (3.13e-1)" "unprognostic (2.77e-2)" "unprognostic (1.76e-2)" "unprognostic (7.76e-2)" "unprognostic (2.03e-1)" "unprognostic (1.12e-2)" "unprognostic (2.10e-3)" "unprognostic (4.49e-2)" "unprognostic (1.32e-1)" "unprognostic (5.59e-3)" 4.6 7.0 2.3 3.8 2.4 7.8 6.8 4.8 2.7 5.0 7.0 6.8 9.4 5.4 9.0 4.3 6.0 3.2 2.4 2.3 2.4 3.6 2.1 3.8 2.2 4.4 3.1 8.6 4.0 3.1 5.8 1.7 4.0 8.4 7.3 4.7 11.0 4.0 2.5 5.9 8.0 3.3 2.9 2.2 5.2 3.2 3.0 2.1 4.6 1.5 2.4 4.2 4.4 4.6 11.2 2.7 3.9 2.6 8.0 15.2 6.7 3.6 2.5 3.9 2.5 4.2 6.0 7.9 3.2 3.5 4.3 4.6 4.5 3.5 5.2 2.9 4.3 5.2 7.1 3.1 4.3 6.1 6.7 6.2 3.0 2.6 3.4 2.5 2.3 9.1 4.6 4.7 7.2 7.2 5.3 5.0 2.5 7.5 3.1 4.9 4.2 2.9 4.1 6.8 3.8 2.8 10.1 10.5 3.3 2.3 14.8 4.0 2.5 3.1 2.6 6.9 4.1 4.9 5.1 8.1 5.6 3.8 5.3 2.0 0.4 0.3 1.5 0.3 0.7 0.2 0.5 0.5 0.3 0.4 0.3 0.6 1.1 1.5 2.6 0.4 0.2 0.2 2.3 2.4 4.8 2.7 2.3 2.4 4.4 3.1 4.0 2.9 3.0 4.6 13.7 38.5 30.7 31.6 6.8 4.0 12.3 3.7 15.9 30.6 26.6 13.6 10.5 17.2 17.3 27.6 29.2 13.1 80.5 37.4 7.9 14.9 2.8 32.7 22.5 9.7 27.9 8.8 37.6 20.4 7.3 15.2 25.0 39.2 8.8 23.2 5.0 11.8 5.6 15.2 44.1 42.0 0.0 10.0 3.9 5.2 33.8 20.2 3.6 15.9 9.3 10.2 127.7 27.6 75.6 19.3 31.6 46.6 34.6 21.5 69.5 6.1 14.1 33.0 26.3 16.0 9.0 4.0 5.9 19.4 4.0 6.8 21.0 21.1 34.5 17.3 GLDC "GCSP, NKH" ENSG00000178445 "Glycine decarboxylase" P23378 9 6532467-6645729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 173.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 31.3;Cytotrophoblasts: 79.0;Extravillous trophoblasts: 41.6;Hepatocytes: 120.5;Oligodendrocyte precursor cells: 52.3;Proximal tubular cells: 31.6;Syncytiotrophoblasts: 46.0" "Cancer enhanced" "Detected in many" "testis cancer: 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 235.7;CACO-2: 58.2;HMC-1: 45.6;RPTEC TERT1: 95.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002318, HPA052887" Enhanced Supported Nucleoplasm,Mitochondria NA NA 740000 "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Nucleoplasm "HPA002318: AB_1849700, HPA052887: AB_2681980" "unprognostic (6.73e-2)" "unprognostic (1.19e-1)" "unprognostic (6.50e-2)" "prognostic unfavorable (5.24e-5)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.74e-1)" "unprognostic (2.47e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.65e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-3)" "unprognostic (1.17e-2)" 0.3 0.3 15.3 1.4 15.5 0.5 0.8 14.7 23.7 0.4 12.9 1.0 0.8 0.4 5.2 3.2 0.7 0.8 0.1 14.8 14.4 38.2 173.5 1.0 1.6 14.0 13.6 0.3 0.1 0.0 4.9 15.2 13.4 0.5 0.4 1.6 1.1 1.0 1.3 4.5 0.8 0.0 13.1 1.2 1.0 3.5 15.8 0.0 5.1 0.1 1.2 1.1 0.1 15.3 0.6 4.9 2.1 25.6 0.2 0.4 235.7 0.1 0.0 0.0 0.1 58.2 0.5 0.3 5.6 0.1 0.7 0.4 0.0 0.7 0.2 1.2 13.4 0.2 0.3 38.3 0.0 0.1 45.6 0.0 0.1 1.8 0.3 1.0 9.0 4.3 0.0 0.5 1.2 1.5 0.9 0.2 27.5 4.6 3.8 1.3 0.0 0.5 95.4 1.0 22.6 11.7 0.0 21.4 0.3 13.9 5.3 0.1 3.0 0.6 0.6 2.6 1.3 1.1 34.4 0.1 0.8 2.4 5.1 0.4 0.1 0.1 0.1 0.0 0.1 0.8 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.1 0.1 0.0 0.3 15.3 15.5 14.7 23.7 14.8 14.4 14.0 13.6 13.4 13.1 15.8 15.3 0.2 0.0 0.0 17.6 1.9 0.0 0.0 0.2 1.2 0.4 1.5 0.6 0.7 11.5 0.1 31.3 0.0 79.0 0.2 0.0 5.9 0.0 12.6 5.4 0.5 0.6 0.0 0.0 21.6 0.2 41.6 0.3 0.0 10.7 0.0 1.1 2.2 120.5 7.0 0.0 15.9 0.0 0.0 2.8 0.3 10.8 0.3 0.4 0.0 1.9 0.0 9.6 0.0 52.3 1.8 0.1 0.0 0.0 15.1 0.0 0.0 31.6 0.0 0.4 0.0 1.7 0.8 4.5 5.1 0.4 0.0 46.0 0.8 0.0 0.0 0.1 GLE1 "GLE1L, hGLE1, LCCS1" ENSG00000119392 "GLE1 RNA export mediator" Q53GS7 9 128504719-128542288 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.0;Late spermatids: 58.1;Spermatocytes: 51.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041689, HPA043538, HPA061560" Supported Supported "Nuclear membrane,Nucleoli" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear membrane" Nucleoli "HPA041689: AB_2677617, HPA043538: AB_2678539, HPA061560: AB_2684560" "unprognostic (8.74e-3)" "unprognostic (2.18e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.49e-4)" "unprognostic (1.75e-1)" "unprognostic (5.58e-2)" "unprognostic (7.91e-2)" "unprognostic (1.90e-1)" "unprognostic (1.91e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.95e-2)" "unprognostic (4.00e-2)" "prognostic favorable (7.04e-4)" "unprognostic (2.62e-1)" "unprognostic (1.99e-3)" "unprognostic (5.64e-2)" 11.6 14.0 9.2 15.7 9.2 15.1 15.7 12.4 11.3 13.0 13.4 17.4 16.2 11.6 10.8 16.4 14.1 7.8 14.9 8.9 8.8 14.1 16.3 12.3 20.4 8.7 9.2 16.2 9.5 17.6 14.1 9.2 8.6 11.8 18.3 16.5 11.1 12.4 22.5 19.1 15.8 12.9 8.4 15.2 12.9 32.0 9.3 25.9 13.3 12.4 22.2 12.8 12.3 8.9 29.6 54.5 26.2 44.9 25.3 25.5 34.6 29.2 24.9 40.2 28.4 36.8 20.1 59.6 23.0 33.0 38.6 101.4 45.9 41.7 34.5 56.9 29.8 30.6 57.8 34.6 28.5 49.9 38.8 18.1 39.7 45.6 48.5 22.3 22.9 54.7 44.7 51.0 46.7 68.6 49.5 35.2 22.2 79.1 46.7 49.8 64.2 79.0 27.3 26.1 30.9 23.1 71.3 42.7 25.9 21.1 78.9 34.9 17.0 42.5 28.1 50.2 41.2 50.9 131.9 45.9 39.9 37.5 46.8 40.0 21.1 24.4 22.1 26.0 18.1 13.4 17.2 20.0 22.1 20.5 15.2 17.7 18.0 27.4 27.5 13.0 22.3 19.8 9.2 9.2 12.4 11.3 8.9 8.8 8.7 9.2 8.6 8.4 9.3 8.9 4.0 9.6 9.0 11.1 11.4 6.5 5.3 10.4 8.6 7.6 8.8 7.6 13.0 5.7 7.2 7.3 8.4 16.1 6.9 13.2 5.9 11.7 77.0 12.2 7.4 3.6 5.4 12.0 14.0 6.2 11.7 7.6 10.2 9.4 9.5 10.9 4.6 14.2 15.7 10.1 15.5 12.7 8.2 15.1 5.7 58.1 10.2 13.5 3.6 10.3 20.0 8.9 15.5 18.1 15.5 8.3 8.0 6.4 13.4 6.1 16.3 13.7 12.6 8.6 13.1 7.7 7.3 51.3 25.5 14.4 6.8 13.3 12.1 7.1 14.1 5.4 GLIPR2 "C9orf19, GAPR-1" ENSG00000122694 "GLI pathogenesis related 2" Q9H4G4 9 36136536-36163913 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 188.5;Langerhans cells: 203.6;Macrophages: 117.6;monocytes: 203.0;NK-cells: 180.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 71.6;HDLM-2: 72.9;TIME: 127.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029478 Approved Uncertain Vesicles,Microtubules NA NA 19000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Microtubules "HPA029478: AB_10670038" "unprognostic (1.57e-2)" "unprognostic (5.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.46e-2)" "unprognostic (1.33e-2)" "unprognostic (9.90e-2)" "unprognostic (2.50e-1)" "unprognostic (1.84e-2)" "unprognostic (4.26e-2)" "unprognostic (3.21e-1)" "unprognostic (5.87e-2)" "prognostic unfavorable (6.54e-7)" "unprognostic (6.57e-3)" "unprognostic (4.94e-1)" "unprognostic (1.02e-1)" "unprognostic (2.43e-2)" 38.5 20.9 17.6 52.7 22.8 73.8 32.4 21.0 22.6 45.9 14.1 73.7 14.7 77.8 15.1 18.6 36.9 24.1 24.2 17.2 19.3 8.8 6.9 62.6 29.9 24.8 22.1 13.3 5.6 2.5 4.9 8.8 22.3 38.3 33.1 2.7 15.3 39.3 7.7 12.2 32.2 63.8 22.8 41.3 25.3 3.4 26.7 18.7 15.8 11.1 19.2 38.8 27.4 27.6 3.7 2.9 20.9 22.3 71.6 33.3 2.4 32.9 20.0 7.8 14.1 1.3 0.3 0.2 10.2 30.9 19.7 0.2 7.9 1.1 4.7 72.9 6.4 8.8 6.2 0.4 27.9 5.7 28.3 23.4 1.0 44.5 7.8 14.0 62.5 22.6 0.4 5.0 17.4 7.9 27.9 15.2 20.1 0.3 10.7 18.9 44.1 1.0 1.6 1.8 5.6 11.3 4.4 2.2 3.6 42.2 2.3 24.0 127.3 10.7 24.8 9.6 28.0 7.8 2.2 12.7 11.0 35.0 2.5 268.6 360.9 540.3 168.4 162.5 89.1 24.4 114.3 108.2 208.3 24.5 47.0 74.7 657.0 125.5 124.9 18.5 132.2 414.0 17.6 22.8 21.0 22.6 17.2 19.3 24.8 22.1 22.3 22.8 26.7 27.6 11.9 3.2 25.4 4.6 22.3 13.4 2.5 14.7 1.8 0.3 46.9 19.0 2.6 2.8 30.9 5.5 0.0 3.8 66.9 14.7 0.0 21.2 0.7 1.8 33.9 13.3 8.4 58.7 1.1 1.3 3.3 54.3 11.7 2.1 52.6 1.9 16.1 0.9 188.5 0.0 0.8 42.4 14.2 83.2 203.6 2.3 18.0 117.6 62.2 2.8 203.0 21.4 180.2 3.0 28.6 5.2 16.1 25.9 22.8 16.0 4.0 1.1 64.3 0.5 46.0 44.7 43.2 0.9 6.4 0.9 10.2 3.4 75.5 10.9 45.3 3.3 GLIS3 "MGC33662, ZNF515" ENSG00000107249 "GLIS family zinc finger 3" Q8NEA6 9 3824127-4348392 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Congenital hypothyroidism, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.2;choroid plexus: 20.5" "Cell type enriched" "Detected in many" 7 "Astrocytes: 649.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 21.5;HSkMC: 29.5;RPTEC TERT1: 20.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056426 Approved Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA056426: AB_2683128" "unprognostic (6.24e-2)" "unprognostic (2.30e-2)" "unprognostic (1.54e-1)" "unprognostic (3.63e-3)" "unprognostic (4.10e-1)" "unprognostic (1.88e-1)" "unprognostic (1.81e-2)" "unprognostic (7.14e-2)" "unprognostic (4.66e-2)" "unprognostic (1.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.63e-1)" "unprognostic (1.91e-3)" "unprognostic (6.88e-3)" "unprognostic (8.54e-2)" "unprognostic (1.04e-1)" "unprognostic (6.35e-2)" 4.3 1.6 5.1 2.1 5.5 0.2 1.9 4.9 4.6 7.8 20.5 2.0 0.7 3.3 2.8 0.5 8.7 6.5 2.9 5.4 10.8 7.8 3.3 3.8 1.1 24.2 18.0 6.6 9.7 2.4 2.4 1.4 11.4 3.3 2.1 1.3 3.1 8.2 1.3 0.8 1.5 2.1 13.7 2.0 1.8 2.8 6.5 0.2 18.6 0.8 0.7 4.0 2.4 13.2 1.0 8.5 2.5 0.0 3.7 9.5 0.4 5.9 21.5 3.1 4.4 1.3 3.4 0.0 4.3 5.5 9.6 0.0 2.0 0.0 6.7 2.5 1.2 0.0 0.4 0.0 11.0 0.9 0.0 29.5 0.0 9.8 1.1 5.8 0.4 0.1 0.0 0.2 2.9 0.4 0.0 1.5 0.2 0.0 0.8 0.0 5.2 0.0 20.8 0.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 5.5 3.4 0.9 3.2 13.3 0.0 0.0 0.0 8.1 0.0 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 5.1 5.5 4.9 4.6 5.4 10.8 24.2 18.0 11.4 13.7 6.5 13.2 8.1 9.6 24.0 649.7 1.0 1.9 9.3 17.1 0.6 1.0 4.6 1.3 1.6 75.8 34.5 69.9 0.0 3.2 0.3 3.7 0.0 51.0 5.2 79.6 17.5 11.2 43.7 0.0 18.3 22.6 3.2 21.9 4.1 82.3 1.3 1.6 6.8 8.3 2.4 0.0 54.2 1.6 12.2 0.8 4.0 2.4 13.7 3.4 3.6 86.2 2.2 15.6 0.0 26.7 4.1 49.1 3.9 11.3 0.0 16.5 2.4 16.4 35.7 0.4 0.0 34.4 19.0 1.3 7.4 0.6 1.3 4.2 1.2 8.8 6.6 6.1 GLOD4 "C17orf25, CGI-150, HC71" ENSG00000167699 "Glyoxalase domain containing 4" Q9HC38 17 757097-783390 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021623, HPA023246, HPA023248" Enhanced Approved Cytosol NA NA 3500000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA021623: AB_1844365, HPA023246: AB_1844366, HPA023248: AB_1844367" "unprognostic (2.82e-1)" "unprognostic (1.80e-1)" "unprognostic (1.33e-1)" "unprognostic (1.45e-2)" "unprognostic (1.99e-1)" "unprognostic (2.11e-1)" "unprognostic (2.88e-1)" "unprognostic (3.35e-1)" "unprognostic (3.13e-2)" "unprognostic (6.27e-2)" "unprognostic (4.86e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.18e-6)" "unprognostic (6.21e-3)" "unprognostic (1.33e-1)" "unprognostic (2.46e-1)" "unprognostic (3.02e-1)" 42.5 46.8 27.4 33.5 31.0 22.5 34.5 25.4 33.3 28.4 33.4 71.3 80.5 31.6 33.6 42.9 44.9 32.6 37.3 30.6 36.4 75.7 67.7 31.5 46.9 27.8 27.9 39.9 40.5 37.6 23.2 36.7 28.8 37.8 48.3 25.6 39.5 27.3 39.8 44.3 72.7 31.9 28.3 36.8 85.3 19.4 35.3 35.2 47.4 23.0 40.0 41.5 22.4 27.5 121.1 106.8 120.9 67.1 52.0 51.5 73.8 94.4 57.6 75.0 56.7 87.4 84.0 142.9 100.2 42.8 69.7 85.5 106.6 60.1 78.0 105.4 91.2 69.0 55.7 115.5 51.6 72.1 87.5 36.2 81.9 75.5 66.0 47.7 70.4 116.9 115.1 90.4 80.2 73.9 124.1 55.3 88.7 118.8 36.3 122.7 49.0 65.9 74.5 81.2 54.8 91.8 74.8 53.6 124.6 75.3 66.6 75.2 92.2 71.0 56.8 99.9 120.4 50.3 100.0 89.1 83.6 79.5 75.9 26.1 51.8 48.7 68.1 64.1 73.2 70.0 81.0 82.2 45.9 75.4 68.9 75.7 7.1 64.0 70.4 47.2 99.1 75.9 27.4 31.0 25.4 33.3 30.6 36.4 27.8 27.9 28.8 28.3 35.3 27.5 52.2 57.7 35.2 11.4 48.5 47.9 40.4 91.1 40.5 39.6 39.2 36.3 30.9 54.3 70.4 101.2 29.2 104.5 43.2 39.3 178.1 77.3 34.0 44.0 34.3 43.8 28.9 54.7 12.7 57.4 85.9 41.5 71.4 40.8 40.4 42.1 31.1 58.8 82.3 13.5 13.6 52.0 97.6 30.1 26.5 63.3 38.8 40.8 67.6 7.5 61.7 39.8 44.3 10.1 13.2 58.7 52.0 46.6 27.5 39.4 110.5 186.1 66.8 38.7 46.0 30.3 45.8 23.5 32.9 53.6 54.8 69.1 53.3 57.2 63.7 39.3 GLP1R GLP-1R ENSG00000112164 "Glucagon like peptide 1 receptor" P43220 6 39048781-39091303 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7;heart muscle: 2.7;pancreas: 7.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.2;Early spermatids: 1.0;Inhibitory neurons: 1.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.1;SCLC-21H: 2.7" "Region enriched" "Detected in many" 4 "basal ganglia: 20.7" "Low region specificity" "Detected in some" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (4.06e-3)" "unprognostic (5.38e-6)" "unprognostic (1.80e-2)" "unprognostic (4.16e-2)" "unprognostic (4.98e-2)" "unprognostic (3.55e-1)" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (9.76e-2)" "unprognostic (3.29e-1)" "unprognostic (1.73e-1)" "unprognostic (8.60e-3)" "unprognostic (2.47e-1)" "unprognostic (1.15e-2)" "unprognostic (1.42e-2)" 0.1 0.0 0.4 0.0 0.9 0.0 0.6 0.3 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 2.7 0.6 3.7 0.1 0.0 0.3 0.1 1.1 0.5 0.0 7.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.9 0.2 1.6 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.5 0.6 3.7 1.1 0.5 1.2 1.1 1.6 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GLRX5 "C14orf87, GRX5, PR01238" ENSG00000182512 "Glutaredoxin 5" Q86SX6 14 95533503-95544724 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 518.5;Erythroid cells: 1134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042465, HPA063716" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA042465: AB_10794048, HPA063716: AB_2685102" "unprognostic (2.57e-1)" "unprognostic (6.76e-2)" "unprognostic (1.60e-2)" "unprognostic (2.69e-2)" "unprognostic (3.72e-2)" "unprognostic (2.43e-3)" "unprognostic (1.29e-1)" "unprognostic (5.41e-2)" "unprognostic (8.28e-2)" "prognostic favorable (1.08e-5)" "unprognostic (1.85e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.83e-10)" "unprognostic (1.44e-1)" "unprognostic (3.81e-2)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" 37.2 52.1 44.1 17.6 44.9 178.8 27.2 43.8 50.2 22.3 46.7 44.8 46.2 19.2 39.0 24.5 23.6 17.5 76.9 46.6 45.8 74.5 105.5 18.3 23.1 43.3 44.5 32.8 31.5 46.3 18.9 37.8 44.3 26.8 37.3 10.1 29.3 29.6 195.0 18.3 33.2 24.4 42.9 20.8 34.2 35.7 46.2 40.3 26.7 168.9 27.0 24.5 15.0 42.9 77.1 92.7 61.4 68.0 74.2 57.5 202.0 54.9 56.1 69.4 69.1 124.8 87.5 111.7 77.4 42.8 39.2 75.5 116.5 79.6 71.5 68.5 94.4 100.3 63.4 202.2 73.5 160.9 96.5 55.4 74.1 49.9 81.1 28.1 76.1 94.4 115.7 88.3 61.2 205.5 133.6 165.9 81.5 89.7 107.8 220.8 184.3 67.8 93.3 89.3 127.9 75.2 54.8 81.3 87.7 59.9 107.7 72.6 55.6 30.5 65.0 77.6 85.7 41.7 57.9 92.0 67.2 99.8 72.2 0.4 2.9 4.8 3.4 4.3 4.9 4.6 4.6 6.0 4.7 5.4 3.7 3.9 1.3 3.9 2.7 9.0 6.2 1.8 44.1 44.9 43.8 50.2 46.6 45.8 43.3 44.5 44.3 42.9 46.2 42.9 78.7 28.9 30.0 7.8 41.1 108.5 58.7 7.5 61.5 38.5 112.8 135.9 150.0 64.3 10.4 95.6 33.3 97.8 66.5 76.3 518.5 15.2 312.0 49.7 61.5 58.9 54.0 1134.9 15.0 15.6 164.9 66.2 46.4 48.3 14.7 110.3 47.2 147.2 58.7 50.5 16.4 72.1 4.1 41.7 58.7 90.2 54.3 50.7 87.2 7.5 21.3 128.1 52.5 12.5 15.2 15.2 39.5 73.7 75.2 108.2 51.8 281.4 9.1 43.0 59.2 61.1 92.7 115.4 79.0 102.2 124.9 53.8 48.8 169.0 88.0 76.6 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182378098-182392206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1443.6" "Group enriched" "Detected in all" 4 "Late spermatids: 8544.2;Muller glia cells: 6247.0" "Cancer enhanced" "Detected in all" "liver cancer: 365.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 656.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 656.8" "Cell line enhanced" "Detected in many" "ASC diff: 1150.8;ASC TERT1: 807.6;HSkMC: 702.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported "Plasma membrane,Mitochondria,Cytosol" NA NA 150000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "CAB008636: AB_1616669, HPA007316: AB_888438, HPA007571: AB_1078980" "prognostic favorable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 753.5 76.0 694.3 156.9 746.5 232.9 573.5 717.5 1237.1 161.4 583.2 157.8 24.4 116.7 115.7 218.7 224.3 105.4 129.7 676.6 764.7 65.3 280.7 221.7 75.2 891.0 783.7 303.0 204.7 32.3 70.5 176.6 767.0 103.4 92.5 891.1 233.5 96.0 1443.6 231.4 148.2 124.1 725.0 216.4 648.2 87.1 811.4 97.0 257.4 472.0 103.2 185.5 292.0 810.4 26.4 10.8 117.2 0.2 1150.8 807.6 86.0 44.1 141.7 25.9 23.4 64.1 26.7 22.4 46.3 85.5 23.8 59.3 51.8 309.4 21.5 61.2 143.3 296.5 47.6 124.8 61.1 132.6 227.2 702.1 363.3 32.9 384.6 39.1 52.8 71.7 254.3 13.3 92.6 15.0 208.2 126.5 87.3 36.8 55.0 74.3 31.3 38.6 45.8 114.0 79.7 52.5 12.4 157.3 17.4 93.3 153.1 165.9 39.7 0.9 1.9 0.8 10.1 4.8 3.4 0.4 22.3 73.9 5.0 396.5 153.4 409.4 42.3 145.8 17.6 11.5 29.9 35.5 80.0 17.8 15.3 25.3 656.8 27.2 130.5 43.7 13.0 172.0 694.3 746.5 717.5 1237.1 676.6 764.7 891.0 783.7 767.0 725.0 811.4 810.4 127.8 125.0 173.8 599.4 37.6 134.7 533.8 1190.7 260.0 105.6 166.6 99.1 216.2 171.6 855.3 82.8 52.1 161.7 113.4 118.3 74.3 124.2 1491.3 140.2 150.0 191.5 325.9 319.7 3.4 116.6 65.9 404.4 388.4 124.6 786.3 88.0 152.8 597.1 798.0 43.7 22.0 256.7 451.6 907.2 614.1 8544.2 487.4 687.4 136.9 74.9 112.7 6247.0 42.2 38.2 330.0 108.1 105.3 375.0 38.7 421.0 10.3 46.6 569.9 176.0 92.1 481.5 218.5 48.2 63.6 186.5 128.3 235.3 108.6 53.3 173.3 1420.5 GLYAT "ACGNAT, GAT" ENSG00000149124 Glycine-N-acyltransferase Q6IB77 11 58640426-58731974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Detoxification "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "kidney: 571.8;liver: 698.0" "Group enriched" "Detected in some" 6 "Hepatocytes: 346.7;Proximal tubular cells: 1261.0" "Group enriched" "Detected in some" 158 "liver cancer: 21.7;renal cancer: 25.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-937: 1.4" "Not detected" "Not detected" "HPA040251, HPA044094" Enhanced NA NA 21000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA040251: AB_2676902, HPA044094: AB_2678807" "unprognostic (2.15e-2)" "unprognostic (9.38e-4)" "unprognostic (4.60e-2)" "unprognostic (1.65e-3)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.69e-1)" 47.0 0.1 0.0 0.1 0.1 0.1 8.5 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 571.8 698.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 1.2 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 11.5 0.0 31.3 0.0 0.1 0.0 0.0 123.3 0.0 6.0 0.0 0.0 0.6 0.0 8.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 346.7 0.0 0.0 0.2 0.0 0.0 10.7 0.0 8.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1261.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 3.8 0.0 0.0 0.0 GLYATL1 "FLJ34646, MGC15397" ENSG00000166840 "Glycine-N-acyltransferase like 1" Q969I3 11 58905398-59043527 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 576.3" "Group enriched" "Detected in some" 4 "Hepatocytes: 234.3;Proximal tubular cells: 797.1" "Group enriched" "Detected in some" 8 "liver cancer: 14.1;prostate cancer: 13.3;renal cancer: 10.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.0;Daudi: 4.9;RPTEC TERT1: 1.5;U-2197: 1.2" HPA039501 Supported Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Cytosol "HPA039501: AB_2676545" "unprognostic (9.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.90e-5)" "unprognostic (3.93e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-1)" "prognostic favorable (3.69e-4)" "unprognostic (3.62e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.03e-5)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 1.3 0.3 0.4 0.1 0.4 0.3 1.6 0.1 0.7 0.1 1.3 0.9 0.0 0.1 0.3 141.4 576.3 0.0 0.1 0.9 0.2 0.0 1.7 2.6 0.0 0.0 1.1 11.1 0.3 0.2 1.9 0.0 0.0 0.6 0.2 0.0 0.3 0.1 2.7 0.1 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.1 0.5 0.4 2.0 0.0 4.9 0.0 0.3 0.4 0.0 0.0 0.0 0.8 0.0 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.0 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.3 0.9 0.2 1.1 0.3 0.3 0.3 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.3 12.8 0.0 14.7 0.0 0.0 0.0 0.1 107.6 0.1 0.0 2.5 0.1 0.5 0.0 8.0 0.7 0.6 0.0 0.1 0.0 0.1 0.0 0.1 5.0 234.3 0.0 0.0 0.8 0.1 0.0 8.1 0.0 0.0 0.0 3.1 1.8 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.0 1.3 0.0 797.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 1.9 0.1 0.9 0.2 GLYATL1B GLYATL1P3 ENSG00000255151 "Glycine-N-acyltransferase like 1B" A0A0U1RQE8 11 59086307-59094786 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 7 "breast: 7.3;lymphoid tissue: 2.8" "Cell type enriched" "Detected in single" 57 "Proximal tubular cells: 5.8" "Cancer enhanced" "Detected in single" "prostate cancer: 0.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Lineage enriched" "Detected in single" 15 "B-cells: 1.5" "Cell line enhanced" "Detected in some" "Daudi: 1.8;T-47d: 1.2;U-266/70: 1.8" HPA039501 Uncertain Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Cytosol "HPA039501: AB_2676545" "unprognostic (1.39e-1)" "unprognostic (3.46e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (5.20e-2)" "unprognostic (2.62e-1)" "unprognostic (2.11e-1)" "unprognostic (3.21e-4)" "unprognostic (3.45e-1)" 0.0 0.0 0.0 0.8 0.0 0.0 7.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.9 0.0 1.8 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GM2A SAP-3 ENSG00000196743 "GM2 ganglioside activator" P17900 5 151212150-151270440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Gangliosidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.7;Hofbauer cells: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 30.9;dendritic cells: 39.6;monocytes: 40.4" "Cell line enhanced" "Detected in all" "BEWO: 207.1;HBEC3-KT: 291.8;hTCEpi: 287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008063 Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 19000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" "HPA008063: AB_1849842" "unprognostic (4.33e-2)" "unprognostic (8.97e-3)" "unprognostic (2.27e-1)" "unprognostic (3.01e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.77e-5)" "unprognostic (1.22e-1)" "unprognostic (1.72e-2)" "unprognostic (1.31e-2)" "unprognostic (1.50e-2)" "unprognostic (5.33e-3)" "unprognostic (9.81e-2)" "unprognostic (4.24e-2)" "unprognostic (4.42e-2)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" 17.4 20.5 29.3 30.0 39.7 20.6 28.0 38.9 31.1 30.8 17.9 19.7 15.8 15.1 30.8 56.2 15.4 23.4 26.2 27.1 34.3 11.4 24.8 39.0 61.4 42.6 37.9 21.3 14.9 28.3 6.6 57.9 44.3 21.1 26.3 11.7 17.0 17.9 7.2 81.8 16.3 20.0 39.0 36.0 15.8 11.6 36.2 72.3 13.0 10.5 77.9 40.3 49.5 46.7 22.3 14.8 15.1 71.7 98.0 48.2 207.1 35.0 75.1 19.0 25.6 30.3 26.1 71.9 35.1 26.9 51.1 60.0 16.7 291.8 27.2 41.4 10.5 11.7 16.8 37.9 23.7 19.1 117.1 65.4 287.0 24.4 16.4 26.0 27.6 85.1 11.4 30.7 30.1 9.6 38.4 18.0 10.2 11.4 32.3 17.7 7.1 46.3 18.4 43.3 3.9 13.4 29.1 133.0 58.3 52.0 30.7 22.5 24.6 46.0 17.6 38.3 10.6 75.2 96.8 187.0 53.1 30.1 19.4 7.6 40.4 2.4 3.7 13.6 2.7 30.9 4.3 3.9 39.6 29.8 6.1 4.8 8.7 4.4 3.4 28.0 5.4 18.6 29.3 39.7 38.9 31.1 27.1 34.3 42.6 37.9 44.3 39.0 36.2 46.7 5.8 16.0 23.0 5.5 25.0 14.9 18.5 63.2 26.7 5.8 5.4 15.5 30.9 0.0 29.7 18.4 2.1 53.6 8.3 4.4 1.9 7.2 0.5 5.7 6.8 7.3 3.6 5.0 2.2 8.1 224.7 10.2 10.7 7.7 69.6 16.3 8.6 24.2 100.8 6.7 2.7 5.4 10.2 55.7 32.5 1.6 8.1 67.8 8.8 2.8 52.5 8.0 7.2 3.5 9.5 6.0 4.7 13.9 28.8 6.7 6.2 5.4 19.9 3.7 0.0 7.9 6.9 1.8 4.2 45.6 23.9 52.5 5.6 6.4 6.7 36.5 GNA14 ENSG00000156049 "G protein subunit alpha 14" O95837 9 77423079-77648322 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 219.1;Early spermatids: 50.2;Hepatic stellate cells: 61.4;Late spermatids: 38.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 95 "basophil: 27.3" "Lineage enriched" "Detected in single" 95 "granulocytes: 27.3" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.3;HUVEC TERT2: 1.6;PC-3: 3.2;THP-1: 1.6;U-2197: 2.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA048886: AB_2680544" "unprognostic (7.80e-3)" "unprognostic (1.10e-2)" "unprognostic (1.09e-2)" "unprognostic (1.18e-3)" "unprognostic (2.03e-1)" "unprognostic (1.53e-4)" "unprognostic (2.48e-6)" "unprognostic (6.35e-3)" "unprognostic (3.34e-1)" "unprognostic (9.04e-2)" "unprognostic (1.21e-1)" "unprognostic (2.43e-1)" "unprognostic (2.92e-2)" "unprognostic (1.04e-3)" "unprognostic (1.79e-1)" "unprognostic (1.75e-3)" "unprognostic (2.03e-1)" 3.4 2.2 7.3 4.0 6.5 0.0 2.4 2.7 8.4 3.6 11.8 5.8 1.7 15.6 5.2 4.8 3.6 4.9 4.1 9.2 4.5 11.7 6.0 8.8 3.3 9.7 5.0 6.0 1.4 1.4 3.1 7.0 7.0 6.8 6.1 0.1 8.0 13.7 0.6 0.9 3.0 13.8 8.1 7.3 3.3 2.1 5.6 0.7 17.6 0.6 2.1 7.6 4.8 13.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.3 1.0 0.3 0.0 0.6 0.0 0.9 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.4 3.2 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.8 0.4 0.0 1.2 0.3 1.6 0.4 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 27.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 7.3 6.5 2.7 8.4 9.2 4.5 9.7 5.0 7.0 8.1 5.6 13.9 2.3 0.0 1.1 219.1 0.2 0.6 2.0 0.2 0.0 0.0 1.0 0.4 0.8 0.0 6.5 0.0 0.0 0.1 0.0 2.6 0.0 0.7 50.2 1.7 4.9 12.8 3.0 2.7 15.8 1.0 0.1 4.2 0.0 1.8 4.5 0.1 61.4 1.2 0.3 0.0 4.4 13.7 2.0 2.5 1.1 38.8 3.7 0.2 1.8 15.9 0.0 0.0 0.0 7.1 12.4 0.1 2.7 1.9 0.0 1.0 0.5 7.1 20.8 0.0 0.0 19.4 0.9 0.4 0.7 0.3 0.6 0.1 0.2 0.5 2.9 4.9 GNA15 GNA16 ENSG00000060558 "G protein subunit alpha 15" P30679 19 3136033-3163749 "Plasma proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.6;esophagus: 108.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 141.5;Langerhans cells: 190.6;Macrophages: 78.3;Suprabasal keratinocytes: 95.8;Urothelial cells: 173.8" "Group enriched" "Detected in all" 4 "cervical cancer: 39.9;head and neck cancer: 46.4;lung cancer: 17.3;pancreatic cancer: 11.9;urothelial cancer: 31.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 67.1" "Group enriched" "Detected in many" 4 "dendritic cells: 67.1;granulocytes: 19.4;monocytes: 29.1" "Cell line enhanced" "Detected in some" "HBEC3-KT: 65.4;HMC-1: 152.1;MOLT-4: 162.4;NB-4: 59.8;REH: 119.3;THP-1: 62.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043113 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA043113: AB_10967343" "prognostic favorable (7.57e-5)" "unprognostic (6.06e-2)" "unprognostic (3.43e-1)" "prognostic favorable (2.01e-4)" "unprognostic (4.34e-2)" "unprognostic (2.09e-1)" "unprognostic (1.14e-2)" "unprognostic (5.38e-3)" "unprognostic (1.82e-1)" "unprognostic (3.22e-2)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (4.26e-6)" "unprognostic (1.04e-1)" "unprognostic (2.16e-3)" "unprognostic (2.36e-1)" "unprognostic (2.07e-1)" 6.8 3.1 4.0 12.4 3.8 75.6 4.6 4.0 7.3 13.3 4.7 2.5 1.7 1.3 0.4 108.8 2.4 4.6 1.9 4.1 4.1 2.0 1.4 13.1 4.2 5.4 4.5 0.8 1.2 0.4 1.4 7.6 5.1 11.6 1.8 0.1 19.5 2.5 0.6 50.8 2.5 3.1 4.9 8.8 4.3 1.4 6.6 32.0 1.2 0.9 12.1 28.1 41.6 6.4 44.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 18.7 0.1 0.1 0.0 0.1 36.2 0.0 65.4 0.0 0.1 0.0 19.1 0.1 0.0 0.0 27.2 152.1 0.0 40.0 0.2 26.2 0.0 0.0 16.6 0.1 0.3 0.0 0.0 162.4 59.8 0.1 2.9 0.0 119.3 0.0 0.2 0.0 23.6 0.2 0.0 4.6 0.2 0.2 0.0 0.0 62.1 0.1 0.0 0.2 0.2 0.3 0.2 0.0 0.1 0.3 29.8 0.1 19.4 29.1 14.3 0.0 21.8 1.1 0.0 2.0 0.3 28.8 0.0 0.0 0.0 6.9 4.4 15.5 67.1 8.7 13.3 4.0 3.8 4.0 7.3 4.1 4.1 5.4 4.5 5.1 4.9 6.6 6.4 1.0 9.6 8.8 0.0 2.2 67.2 141.5 65.5 9.1 0.2 7.4 3.7 0.5 0.0 39.0 3.7 0.0 0.5 27.6 0.5 0.0 0.7 0.5 1.4 0.5 3.1 6.6 21.0 1.3 0.0 0.8 2.5 3.6 3.9 34.3 0.0 0.7 0.0 66.5 0.0 0.4 2.2 57.0 36.2 190.6 0.8 0.0 78.3 21.4 7.5 32.0 0.0 0.0 0.0 0.2 13.2 0.3 0.0 3.6 69.3 0.0 0.1 21.7 0.1 19.7 0.3 3.3 4.0 2.0 38.0 95.8 0.4 19.6 0.1 1.4 173.8 GNAI1 ENSG00000127955 "G protein subunit alpha i1" P63096 7 79768028-80226181 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 220.0;Oligodendrocytes: 410.7;Suprabasal keratinocytes: 214.2;Syncytiotrophoblasts: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "NK-cell: 12.8" "Lineage enriched" "Detected in many" 6 "NK-cells: 12.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022449, HPA042141" Approved Supported Nucleoplasm,Nucleoli,Centrosome NA NA 1600000 "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Centrosome "Nucleoplasm, Nucleoli" "CAB022449: , HPA042141: AB_2677870" "unprognostic (2.29e-1)" "unprognostic (2.83e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-1)" "unprognostic (7.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.92e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (5.09e-4)" "unprognostic (9.78e-2)" "unprognostic (1.26e-1)" "unprognostic (4.48e-1)" "unprognostic (9.41e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.12e-1)" "unprognostic (1.94e-2)" "unprognostic (1.53e-1)" 47.5 26.2 8.9 2.6 18.8 0.4 34.9 14.9 17.7 18.5 4.4 25.4 4.7 14.8 0.7 19.7 10.9 3.2 9.4 10.8 13.3 36.6 15.2 15.2 2.0 18.8 15.0 17.1 4.5 1.3 10.9 13.6 18.4 8.8 2.6 1.5 10.4 3.0 6.2 47.9 9.9 4.1 15.5 5.9 17.7 13.0 14.2 1.3 14.2 2.9 1.5 24.7 19.9 36.6 2.2 18.6 10.5 0.0 14.5 7.9 9.1 14.3 7.2 5.5 8.7 0.0 3.4 0.0 4.5 9.3 5.1 2.6 7.0 9.5 5.4 0.0 11.9 10.4 12.9 1.2 14.8 1.8 0.0 12.0 19.9 4.1 9.5 4.4 3.5 0.0 0.0 0.1 7.7 0.6 0.0 0.1 6.1 0.2 11.0 8.6 5.2 7.8 15.7 7.0 12.5 9.2 13.5 0.0 10.3 5.4 2.0 0.3 13.0 21.8 15.6 5.1 4.4 0.0 0.0 0.2 6.1 1.2 10.2 1.3 0.4 0.4 0.1 0.4 0.0 0.0 0.1 0.1 1.9 0.1 1.1 0.5 0.3 12.8 1.0 0.2 0.1 0.4 8.9 18.8 14.9 17.7 10.8 13.3 18.8 15.0 18.4 15.5 14.2 36.6 121.1 19.2 13.8 11.4 0.9 220.0 20.6 81.6 35.3 3.9 7.0 7.7 6.7 21.5 42.3 29.5 0.0 83.6 1.3 11.1 88.0 7.2 1.7 23.2 58.5 31.5 19.9 4.2 71.4 3.8 84.6 35.9 4.6 40.3 30.3 43.9 17.5 20.0 10.0 26.9 77.4 7.8 36.7 1.0 28.6 7.0 33.5 3.9 103.2 4.7 2.9 49.1 0.0 53.3 410.7 9.4 6.3 74.4 1.2 17.4 0.9 18.4 36.8 5.0 111.7 10.6 70.8 9.7 45.7 31.9 214.2 183.5 2.9 2.9 10.7 19.2 GNAI3 87U6 ENSG00000065135 "G protein subunit alpha i3" P08754 1 109548615-109600195 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 350.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022099, HPA042141" Approved Approved Nucleoplasm,Nucleoli,Centrosome NA NA 1400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 41: Macrophages - Immune response" Centrosome "Nucleoplasm, Nucleoli" "CAB022099: , HPA042141: AB_2677870" "unprognostic (2.19e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.44e-2)" "unprognostic (2.59e-1)" "unprognostic (9.45e-3)" "prognostic unfavorable (5.30e-6)" "unprognostic (2.56e-3)" "unprognostic (2.18e-2)" "prognostic favorable (4.59e-4)" "unprognostic (1.83e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (7.27e-2)" "unprognostic (1.39e-1)" "unprognostic (1.25e-2)" "unprognostic (1.66e-2)" 12.7 8.2 5.8 14.2 6.1 27.7 11.9 7.3 7.5 10.9 8.6 11.8 10.4 12.1 8.0 21.8 8.0 11.3 4.2 6.0 6.5 11.2 15.3 9.7 14.1 6.7 5.9 8.8 9.3 8.9 1.8 14.8 6.8 10.3 11.8 17.8 7.7 9.0 3.8 18.4 10.6 13.6 6.3 11.4 9.0 8.7 6.2 14.2 8.0 5.5 15.9 15.5 4.0 7.3 48.3 16.4 31.0 17.3 28.4 35.0 25.7 35.3 28.6 36.0 35.5 24.4 16.1 25.3 22.4 37.6 21.6 24.5 30.0 35.3 49.4 29.2 18.0 22.1 26.3 21.9 25.1 34.9 18.8 25.2 30.4 41.3 27.8 24.2 42.8 19.1 29.8 24.2 35.5 32.9 27.3 28.4 31.3 23.0 19.1 19.2 73.6 16.6 37.4 35.4 19.5 34.9 24.7 27.6 39.4 22.8 21.1 30.5 36.7 29.4 40.7 44.9 39.2 25.6 30.2 29.2 47.6 34.4 47.1 32.4 29.7 57.8 21.1 44.3 22.4 20.1 20.4 20.6 31.9 17.1 16.8 19.4 53.8 19.9 44.6 14.2 23.8 36.3 5.8 6.1 7.3 7.5 6.0 6.5 6.7 5.9 6.8 6.3 6.2 7.3 104.0 44.8 31.5 17.0 76.6 151.2 104.3 92.2 63.2 29.9 67.7 45.3 14.3 37.1 61.0 58.8 350.3 80.3 98.8 63.9 64.6 97.9 14.7 65.5 71.5 82.6 84.3 43.8 37.5 101.7 153.7 69.2 55.5 110.9 46.3 50.1 56.7 57.2 107.9 25.2 36.4 72.3 59.0 115.0 106.9 9.4 48.7 127.4 74.7 31.9 102.4 47.9 45.3 35.7 31.3 101.6 58.9 47.4 66.3 72.5 48.9 53.5 51.7 26.2 52.6 59.0 77.6 68.6 54.7 82.1 188.4 106.9 94.3 51.7 63.5 143.0 GNAQ "G-ALPHA-q, GAQ" ENSG00000156052 "G protein subunit alpha q" P50148 9 77716097-78031811 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 556.6;Excitatory neurons: 405.6;Microglial cells: 394.4;Oligodendrocyte precursor cells: 338.3;Oligodendrocytes: 495.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 27.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 27.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010036, HPA048886" Uncertain Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA 800000 "Cluster 38: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB010036: AB_631536, HPA048886: AB_2680544" "unprognostic (2.10e-1)" "unprognostic (8.53e-2)" "unprognostic (1.45e-1)" "unprognostic (4.37e-2)" "unprognostic (1.87e-1)" "unprognostic (6.83e-3)" "unprognostic (1.05e-1)" "unprognostic (3.84e-2)" "unprognostic (2.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.11e-7)" "unprognostic (1.90e-1)" "unprognostic (3.13e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" 23.5 21.3 37.2 18.8 42.2 43.8 20.1 35.8 51.3 21.1 19.3 30.3 14.5 23.7 18.7 23.2 16.9 20.1 8.6 51.0 38.5 20.9 22.0 31.1 9.9 40.5 42.7 22.4 14.6 16.3 12.5 21.7 39.9 21.2 27.2 10.4 16.8 25.7 10.5 8.9 16.8 27.4 42.4 11.3 27.9 11.5 45.5 19.7 23.1 11.8 9.1 23.5 13.8 48.5 30.6 34.1 29.8 32.0 34.9 35.5 42.8 40.7 29.7 16.6 20.6 10.5 24.1 0.1 32.0 35.5 24.5 48.5 22.5 23.4 20.6 1.1 12.5 83.0 29.0 21.4 31.4 51.8 30.0 24.3 28.0 33.9 32.5 34.3 42.7 70.3 14.8 0.2 29.5 38.5 58.8 31.0 24.0 46.5 4.7 22.0 36.5 0.3 37.8 64.5 33.1 49.6 29.3 23.3 30.5 27.5 22.2 18.3 55.0 29.2 1.9 41.9 24.0 0.2 0.1 0.3 20.3 28.9 32.0 27.0 2.5 5.7 0.8 2.2 1.7 0.9 2.0 1.1 2.8 0.9 2.1 1.7 8.9 3.6 4.5 3.2 2.2 1.5 37.2 42.2 35.8 51.3 51.0 38.5 40.5 42.7 39.9 42.4 45.5 48.5 117.7 176.3 97.5 556.6 4.8 47.3 38.4 42.7 39.3 34.0 75.6 54.5 6.0 58.6 48.3 77.3 16.7 47.4 33.4 137.0 7.9 36.2 18.9 57.5 64.2 107.3 92.3 58.0 405.6 39.7 53.2 51.7 70.8 76.0 50.7 40.2 98.6 64.0 53.7 82.4 242.0 92.5 30.5 139.5 173.9 11.1 39.4 128.8 48.0 394.4 114.6 40.5 8.2 338.3 495.2 54.2 60.7 52.3 6.2 70.5 52.9 45.4 67.0 5.0 26.3 62.3 40.8 5.6 13.2 46.3 21.6 29.0 25.0 45.2 75.4 70.1 GNB2 ENSG00000172354 "G protein subunit beta 2" P62879 7 100673567-100679174 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010032, HPA040736" Approved Supported "Plasma membrane" NA NA 940000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010032: AB_2263466, HPA040736: AB_2677106" "unprognostic (1.55e-1)" "unprognostic (5.76e-2)" "unprognostic (1.01e-3)" "unprognostic (2.76e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (3.68e-3)" "unprognostic (3.52e-1)" "unprognostic (6.58e-2)" "unprognostic (2.54e-1)" "unprognostic (9.79e-3)" "unprognostic (1.70e-1)" "unprognostic (3.75e-2)" "unprognostic (1.24e-1)" "unprognostic (3.19e-1)" "unprognostic (5.29e-2)" "unprognostic (2.98e-1)" 198.4 211.0 131.4 128.3 137.3 207.5 188.0 112.3 179.6 209.4 103.8 168.0 103.2 182.4 63.7 328.4 179.8 105.5 175.9 130.2 138.1 186.1 185.8 210.1 107.9 140.3 130.1 175.3 184.8 98.9 203.3 107.4 123.6 183.0 83.6 20.1 190.8 113.6 175.9 295.5 143.5 113.5 126.3 225.9 172.4 92.9 137.6 90.2 144.8 90.2 105.7 165.2 217.7 120.7 358.6 268.6 222.7 272.5 169.8 199.9 194.3 208.4 288.4 294.3 241.7 205.3 333.7 157.7 216.0 311.3 332.2 243.0 177.7 312.6 103.0 216.9 152.1 120.8 198.7 171.3 282.4 157.7 254.5 259.5 291.1 304.2 244.6 237.6 343.6 132.5 228.6 303.3 270.4 980.0 249.5 450.3 173.5 225.1 290.1 234.3 136.3 253.8 235.4 291.3 241.0 380.1 278.0 449.2 201.3 125.3 192.4 192.1 325.8 313.8 346.8 619.2 266.6 88.8 111.9 240.9 237.1 349.7 443.6 27.6 28.6 70.9 17.5 42.7 16.2 13.6 17.9 15.4 28.1 18.1 11.8 12.4 117.2 15.4 35.9 23.8 23.5 12.5 131.4 137.3 112.3 179.6 130.2 138.1 140.3 130.1 123.6 126.3 137.6 120.7 138.1 57.7 97.0 16.0 104.1 151.8 159.3 72.9 148.0 10.4 105.4 106.0 35.0 100.1 55.5 84.6 4.2 172.4 89.4 285.4 162.4 163.7 32.6 133.5 106.8 136.5 180.4 127.7 12.7 218.7 312.1 117.6 135.1 127.2 44.4 97.6 126.0 69.9 264.4 72.3 10.8 211.2 75.3 198.6 198.8 20.1 144.8 193.5 140.5 15.9 160.8 128.2 96.8 5.0 6.9 257.1 285.6 130.1 122.5 226.5 162.3 107.0 68.3 8.5 65.7 62.0 162.2 34.3 69.6 240.7 194.8 293.9 117.8 88.1 192.2 259.5 GNB4 ENSG00000114450 "G protein subunit beta 4" Q9HAV0 3 179396088-179451476 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 81.1;Kupffer cells: 98.1;Macrophages: 66.8;Microglial cells: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 143.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018383, CAB018737, HPA040736" Supported Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB018383: AB_631542, CAB018737: AB_640712, HPA040736: AB_2677106" "unprognostic (2.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (5.97e-3)" "unprognostic (2.12e-1)" "unprognostic (1.44e-2)" "unprognostic (8.28e-2)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (1.90e-3)" "unprognostic (3.13e-2)" "unprognostic (8.90e-2)" "unprognostic (2.80e-3)" 14.9 6.3 8.7 21.9 19.2 33.7 12.4 7.3 11.2 11.5 2.9 9.5 5.9 9.2 3.7 21.9 7.0 15.2 13.9 9.6 8.7 5.9 7.8 16.0 17.7 15.5 8.5 5.8 2.8 2.7 3.0 21.8 14.5 4.5 8.6 2.0 4.7 4.0 3.1 34.1 6.4 23.5 14.5 18.1 7.4 4.3 10.9 7.9 6.3 5.7 11.5 13.2 6.8 19.7 33.4 15.4 37.7 0.8 23.8 41.5 44.1 46.7 33.1 54.1 61.3 0.8 3.7 61.6 9.9 54.3 49.7 0.6 36.4 43.1 56.7 143.6 29.2 71.3 54.9 0.7 23.4 62.3 16.2 32.9 6.6 42.4 21.6 12.0 59.3 13.7 18.7 0.8 42.8 1.3 32.8 24.3 18.9 0.2 19.3 61.4 49.2 25.3 34.9 1.9 7.0 20.5 37.5 33.0 61.1 23.0 67.5 26.1 45.3 45.1 27.4 13.6 61.6 0.3 0.9 0.8 24.7 52.8 35.4 5.6 21.3 11.0 0.2 27.8 0.1 6.7 0.4 0.3 24.9 13.6 0.4 0.3 14.5 3.4 23.5 12.8 0.6 8.8 8.7 19.2 7.3 11.2 9.6 8.7 15.5 8.5 14.5 14.5 10.9 19.7 40.0 25.6 12.8 17.9 20.1 18.7 1.8 2.5 13.6 1.7 14.3 12.3 15.6 0.0 12.3 3.7 6.2 13.8 11.5 0.1 3.9 1.1 1.2 15.6 22.9 42.9 0.0 22.9 18.6 1.6 18.7 26.6 3.6 10.8 10.8 16.2 53.2 0.9 81.1 1.7 18.4 0.0 2.0 98.1 17.4 1.4 10.2 66.8 14.2 91.8 59.9 0.8 2.1 11.6 7.7 2.8 0.0 15.8 8.1 2.6 0.2 0.2 11.3 4.0 26.3 9.9 41.8 2.3 16.8 23.4 25.4 4.1 2.9 14.7 0.0 1.3 GNG12 ENSG00000172380 "G protein subunit gamma 12" Q9UBI6 1 67701475-67833467 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057790, HPA062208" Enhanced Supported Approved Mitochondria NA NA 550000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA057790: AB_2683527, HPA062208: AB_2684711" "unprognostic (5.18e-2)" "unprognostic (1.76e-3)" "unprognostic (4.46e-3)" "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (4.71e-2)" "unprognostic (5.29e-2)" "unprognostic (5.84e-3)" "unprognostic (5.50e-2)" "unprognostic (3.41e-2)" "unprognostic (4.46e-3)" "unprognostic (8.13e-2)" "unprognostic (4.12e-3)" "unprognostic (2.33e-2)" "unprognostic (9.33e-2)" "unprognostic (7.78e-2)" "unprognostic (2.14e-3)" 63.4 57.0 14.4 28.5 12.3 0.3 50.1 10.4 14.0 59.3 13.5 68.4 122.0 59.7 27.7 82.0 43.4 59.3 34.5 13.7 19.5 79.2 44.8 34.3 12.0 21.9 29.1 47.9 25.2 54.7 13.1 60.2 16.9 38.3 65.7 6.6 26.6 47.6 12.9 80.4 110.8 73.9 18.6 56.2 42.7 17.7 16.4 15.9 59.8 19.7 22.7 56.5 46.5 18.7 60.5 55.5 58.0 31.5 241.2 207.9 59.5 182.9 237.2 157.9 141.0 26.5 58.2 0.1 75.9 258.0 98.8 44.2 36.6 150.0 275.7 0.5 28.1 1.0 46.0 0.1 96.0 0.1 3.0 125.7 87.8 168.7 221.8 221.1 251.9 0.0 3.6 0.3 175.6 10.2 0.1 0.5 44.1 65.7 68.3 0.3 119.6 0.9 151.8 53.5 13.2 26.8 126.8 52.1 248.4 48.8 26.9 1.1 326.7 182.5 118.8 332.0 114.5 3.0 0.3 0.5 115.3 7.1 252.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 12.3 10.4 14.0 13.7 19.5 21.9 29.1 16.9 18.6 16.4 18.7 49.7 54.5 32.2 54.5 2.1 201.3 78.8 53.3 78.6 2.1 52.4 37.1 26.7 35.8 42.8 58.8 6.2 61.8 0.9 243.1 74.3 96.2 14.6 51.8 20.6 67.0 34.7 5.3 0.5 138.5 105.6 82.6 45.3 49.3 3.8 21.3 76.1 45.6 27.9 3.3 15.3 56.3 30.5 18.2 32.4 16.6 71.4 6.2 78.2 21.5 3.6 3.0 0.0 63.3 1.3 143.7 99.9 75.6 0.2 119.9 227.3 177.9 79.2 18.9 52.6 54.8 71.7 1.8 18.8 83.1 216.8 175.9 4.5 107.1 61.8 109.1 GNG7 FLJ00058 ENSG00000176533 "G protein subunit gamma 7" O60262 19 2511219-2702694 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "brain: 360.9" "Cell type enhanced" "Detected in many" "B-cells: 145.4;Distal tubular cells: 123.3;Horizontal cells: 169.9;Oligodendrocyte precursor cells: 102.5;Oligodendrocytes: 206.1;Plasma cells: 169.7" "Cancer enhanced" "Detected in all" "glioma: 21.9;melanoma: 20.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 57.2;naive B-cell: 50.1;plasmacytoid DC: 48.0" "Group enriched" "Detected in many" 4 "B-cells: 57.2;dendritic cells: 48.0" "Cell line enhanced" "Detected in many" "Daudi: 22.3;REH: 66.5;SK-MEL-30: 31.2;U-266/70: 61.0;U-266/84: 30.0" "Region enriched" "Detected in all" 6 "basal ganglia: 1277.2" HPA057790 Supported Supported NA NA 72000 "Cluster 43: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA057790: AB_2683527" "unprognostic (3.97e-3)" "unprognostic (1.16e-4)" "unprognostic (4.92e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-1)" "unprognostic (8.42e-4)" "prognostic favorable (3.05e-4)" "prognostic favorable (1.35e-5)" "unprognostic (1.27e-2)" "unprognostic (4.95e-2)" "prognostic favorable (3.71e-4)" "unprognostic (1.27e-1)" "prognostic favorable (0.00e+0)" "unprognostic (6.96e-2)" "unprognostic (1.46e-1)" "unprognostic (6.36e-2)" "unprognostic (4.96e-2)" 3.5 5.7 70.8 5.3 360.9 6.6 4.4 83.9 127.9 5.5 14.0 6.7 5.2 7.2 5.1 12.0 8.2 3.5 26.4 70.1 66.0 10.5 4.2 4.0 9.9 97.2 87.9 12.2 8.0 6.2 17.4 1.4 76.8 9.5 3.1 15.1 26.0 5.7 3.4 2.6 14.2 3.5 76.0 19.4 6.8 8.9 154.1 2.7 5.8 8.1 9.4 7.9 3.3 81.4 0.2 0.0 3.2 7.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.7 22.3 1.0 0.3 0.3 0.2 3.5 0.0 0.1 0.0 3.1 0.6 0.1 2.7 1.6 0.0 12.9 0.4 0.5 0.0 0.2 0.2 0.0 2.7 0.3 14.2 0.0 2.2 0.6 1.4 2.6 0.4 1.4 66.5 0.0 6.2 0.3 0.0 0.1 9.2 0.1 0.1 31.2 2.1 0.4 5.6 0.1 0.1 3.0 0.2 0.2 61.0 30.0 4.7 0.2 7.0 16.5 3.5 1.5 8.0 0.4 0.5 1.1 57.2 0.5 0.4 6.0 50.1 1.2 0.7 11.8 0.2 0.1 48.0 0.0 3.0 70.8 360.9 83.9 127.9 70.1 66.0 97.2 87.9 76.8 76.0 154.1 81.4 14.5 6.4 4.2 40.8 145.4 2.5 13.0 0.3 5.2 10.5 22.9 30.1 55.1 15.7 3.3 9.2 8.4 0.6 56.1 0.9 123.3 17.0 5.4 2.1 2.3 11.7 6.1 8.6 26.5 4.8 1.1 6.6 5.6 3.5 12.7 8.6 19.2 11.4 63.2 169.9 38.8 2.0 0.0 8.5 15.0 11.4 2.5 12.3 51.6 45.9 11.2 84.7 3.1 102.5 206.1 2.7 1.8 2.6 169.7 7.5 0.7 22.6 2.9 11.1 6.6 7.1 5.4 2.7 2.6 1.5 2.0 3.4 6.9 2.1 2.2 7.2 GOLM2 "CASC4, DKFZp459F1927, H63" ENSG00000166734 "Golgi membrane protein 2" Q6P4E1 15 44288719-44415758 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 19.9;Cardiomyocytes: 24.0;Cytotrophoblasts: 16.3;dendritic cells: 16.1;Extravillous trophoblasts: 19.4;Fibroblasts: 18.2;Hofbauer cells: 27.3;Syncytiotrophoblasts: 12.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043015, HPA049488" Enhanced Enhanced "Golgi apparatus" NA NA 1200000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA043015: AB_2678271, HPA049488: AB_2680790" "unprognostic (2.64e-2)" "unprognostic (2.63e-1)" "unprognostic (3.38e-1)" "unprognostic (1.81e-2)" "unprognostic (8.08e-2)" "unprognostic (1.35e-1)" "unprognostic (1.20e-2)" "unprognostic (2.20e-1)" "unprognostic (2.40e-1)" "unprognostic (1.68e-2)" "unprognostic (4.99e-2)" "unprognostic (2.60e-2)" "prognostic favorable (1.45e-5)" "unprognostic (2.15e-1)" "unprognostic (3.56e-2)" "unprognostic (9.65e-2)" "unprognostic (1.12e-1)" 39.5 84.5 48.5 32.4 47.0 16.5 43.2 43.1 59.2 57.9 62.4 45.7 28.8 50.4 53.5 23.7 53.8 50.5 33.1 42.8 52.6 54.0 60.9 40.9 30.8 49.6 51.5 55.3 37.4 82.0 38.7 34.4 46.9 67.5 43.8 33.7 47.8 56.1 22.3 13.2 29.8 44.4 46.7 35.4 49.4 34.6 52.9 28.9 84.6 26.3 29.5 39.2 24.3 52.7 45.0 38.7 51.9 92.6 141.4 121.8 32.0 78.6 125.2 44.9 57.1 19.3 80.0 13.5 106.4 119.3 47.8 53.8 34.4 25.5 48.2 64.6 19.5 21.4 41.8 35.9 65.1 42.5 68.1 72.1 28.3 49.8 38.4 126.8 53.4 34.2 33.0 103.4 56.2 23.2 36.7 33.2 14.8 60.8 27.5 30.5 29.3 43.3 58.8 54.4 23.3 53.2 60.7 57.0 26.6 28.1 64.1 49.2 76.4 78.1 39.8 112.5 69.5 79.0 145.1 27.9 92.6 58.5 51.7 20.9 14.7 20.8 15.2 9.8 16.3 11.9 12.4 15.2 12.0 10.7 9.5 9.9 37.8 10.5 18.2 10.6 13.2 13.6 48.5 47.0 43.1 59.2 42.8 52.6 49.6 51.5 46.9 46.7 52.9 52.7 19.9 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 16.3 16.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 19.4 18.2 0.0 0.0 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 12.7 2.9 0.0 0.0 0.0 GOLT1A "CGI-141, FLJ42654, GOT1, MGC62027, YMR292W" ENSG00000174567 "Golgi transport 1A" Q6ZVE7 1 204198163-204213988 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 190.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 131.3;Proximal enterocytes: 206.8" "Cancer enriched" "Detected in many" 6 "liver cancer: 80.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 18.0;CAPAN-2: 20.0;Hep G2: 25.9;MCF7: 43.5;OE19: 16.1;RT4: 27.7;SK-BR-3: 27.2" "Region enhanced" "Detected in many" "cerebral cortex: 9.0" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.43e-1)" "unprognostic (1.13e-1)" "unprognostic (2.22e-3)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (6.20e-3)" "unprognostic (2.14e-1)" "unprognostic (8.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.26e-2)" "unprognostic (7.33e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.35e-5)" "unprognostic (1.37e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-3)" "prognostic favorable (1.51e-4)" 0.3 0.1 6.1 0.4 9.2 0.0 5.3 7.0 5.3 10.9 3.9 5.6 47.4 0.3 10.7 0.5 3.3 1.6 0.1 4.3 11.2 16.2 190.7 8.3 0.1 4.7 5.3 0.1 22.3 18.3 30.4 3.5 4.7 5.3 5.0 1.5 3.4 2.1 0.3 0.5 45.5 0.3 4.5 0.1 8.2 2.6 11.6 0.8 0.7 0.0 0.2 13.1 0.4 2.8 0.5 8.2 0.0 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 18.0 20.0 0.0 0.7 0.2 0.0 0.6 0.0 0.1 0.1 0.0 0.3 0.1 0.0 25.9 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 43.5 0.0 0.1 4.0 16.1 0.2 0.0 0.1 0.4 8.5 27.7 1.3 1.8 0.8 27.2 0.1 0.7 8.9 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 6.1 9.2 7.0 5.3 4.3 11.2 4.7 5.3 4.7 4.5 11.6 2.8 0.1 0.0 19.5 0.3 0.1 0.0 12.7 2.6 2.8 1.7 7.2 4.7 0.2 40.0 5.1 16.5 0.0 13.3 0.1 7.0 13.7 29.2 0.9 0.5 0.1 0.3 10.3 0.0 2.2 19.1 0.5 1.1 8.2 2.0 1.3 1.4 1.8 131.3 1.3 1.7 0.7 7.8 2.0 1.6 0.0 0.4 0.0 0.2 1.8 0.0 0.0 0.0 0.0 4.5 0.1 18.7 5.6 0.0 0.0 15.0 206.8 14.7 0.3 0.2 0.0 0.3 0.3 2.9 0.9 1.4 0.1 26.4 0.5 0.2 12.5 20.5 GOT1 AST1 ENSG00000120053 "Glutamic-oxaloacetic transaminase 1" P17174 10 99396870-99430624 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Amino-acid biosynthesis" "Aminotransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 511.1;liver: 369.5;skeletal muscle: 489.9;tongue: 1011.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 449.0;Distal tubular cells: 240.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064532, HPA072629" Enhanced Supported Nucleoplasm,Cytosol NA Yes 100000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA064532: AB_2685279, HPA072629: AB_2686540" "unprognostic (6.40e-2)" "prognostic favorable (6.23e-4)" "unprognostic (5.99e-2)" "unprognostic (2.84e-2)" "unprognostic (2.82e-1)" "unprognostic (2.96e-2)" "unprognostic (5.25e-2)" "unprognostic (1.08e-3)" "unprognostic (6.67e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (1.79e-1)" "prognostic favorable (3.72e-13)" "unprognostic (1.93e-2)" "unprognostic (4.23e-1)" "unprognostic (6.85e-2)" "unprognostic (1.00e-1)" 14.7 54.9 67.8 14.7 71.1 8.0 22.7 70.3 119.1 53.1 82.6 50.9 62.0 13.1 25.9 42.7 17.9 49.0 511.1 70.0 77.6 143.1 369.5 15.5 14.1 83.5 55.0 18.1 34.0 142.4 22.5 14.4 83.7 22.7 59.2 106.2 48.6 27.4 489.9 23.9 45.8 21.4 48.4 16.9 58.9 33.6 69.1 17.7 47.7 1011.6 30.3 22.3 21.0 70.1 73.7 40.3 46.0 114.4 35.1 30.7 127.1 58.9 108.7 101.8 109.8 89.9 56.4 71.9 20.4 50.2 89.2 88.6 107.1 78.9 105.8 25.7 46.7 28.1 46.7 114.3 184.9 77.9 44.0 47.3 82.5 86.9 228.4 69.5 49.5 48.6 71.1 106.2 65.4 64.9 42.5 56.5 29.2 118.7 56.1 45.5 44.4 72.8 173.7 37.5 19.6 28.7 44.8 59.3 222.6 66.8 115.7 27.1 23.3 25.4 56.3 28.0 68.7 76.8 99.7 74.3 65.4 40.8 34.1 4.0 8.7 6.8 19.7 25.8 18.4 17.6 21.5 20.7 21.9 21.2 15.6 22.7 0.8 20.5 31.5 36.4 27.6 15.6 67.8 71.1 70.3 119.1 70.0 77.6 83.5 55.0 83.7 48.4 69.1 70.1 10.3 16.0 16.2 26.1 38.8 11.9 41.8 82.7 24.5 95.6 18.8 21.2 449.0 72.9 34.4 73.5 62.6 35.9 10.7 62.1 240.7 51.9 166.7 17.8 9.3 16.7 19.7 39.5 47.4 30.8 18.1 23.5 76.9 21.5 31.8 20.2 17.2 191.8 31.6 75.7 63.3 45.3 54.9 12.4 6.9 24.1 11.1 13.0 49.8 13.1 10.5 36.6 6.2 21.1 37.2 27.6 34.4 14.3 22.4 13.1 97.0 163.3 27.9 76.5 13.1 15.2 20.5 116.7 10.4 40.9 10.4 55.1 14.6 47.0 66.4 42.3 GPAM "GPAT1, KIAA1560, MGC26846" ENSG00000119927 "Glycerol-3-phosphate acyltransferase, mitochondrial" Q9HCL2 10 112149865-112215377 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 305.7;liver: 144.1" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Hepatocytes: 184.5;Horizontal cells: 45.4" "Cancer enriched" "Detected in all" 5 "liver cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 250.3;Hep G2: 71.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046339, HPA060090" Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA046339: AB_2679627, HPA060090: AB_2684202" "unprognostic (1.82e-1)" "unprognostic (6.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.30e-1)" "unprognostic (6.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" "unprognostic (4.59e-1)" "unprognostic (4.80e-1)" "unprognostic (2.37e-2)" "unprognostic (5.44e-2)" "prognostic favorable (4.54e-6)" "unprognostic (2.84e-1)" "unprognostic (4.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.37e-1)" 305.7 33.9 14.9 4.8 17.1 3.4 67.7 12.2 14.0 3.0 6.9 6.4 4.0 4.2 75.1 2.9 3.1 6.0 12.3 12.4 13.0 4.4 144.1 4.1 4.6 12.9 16.0 5.3 5.0 4.3 2.1 3.0 12.1 3.9 4.7 5.1 17.2 5.3 8.3 3.2 6.1 4.9 11.5 2.9 4.9 5.6 15.7 3.6 12.4 8.8 4.3 4.8 2.6 10.5 9.9 7.4 9.7 12.9 250.3 9.1 12.7 9.2 10.5 6.6 5.1 17.3 5.7 6.9 5.0 6.5 6.1 12.3 15.5 7.9 12.3 5.0 8.4 6.4 7.9 71.8 7.7 11.2 3.4 43.8 13.1 11.7 23.6 49.7 5.8 9.7 8.5 6.1 7.7 5.6 9.6 8.8 8.1 5.6 10.1 9.7 25.4 5.1 4.3 6.8 4.1 12.1 12.8 6.1 14.5 8.9 6.3 4.0 4.4 7.5 4.6 9.4 14.8 6.1 7.3 14.3 8.8 9.8 5.8 0.0 0.3 0.1 0.7 0.4 0.9 0.5 0.5 0.5 0.4 1.1 0.5 0.9 0.0 0.3 0.3 0.6 0.6 0.3 14.9 17.1 12.2 14.0 12.4 13.0 12.9 16.0 12.1 11.5 15.7 10.5 9.1 9.6 27.1 90.8 5.2 0.4 0.8 1.6 4.6 5.3 8.1 8.4 18.9 20.0 4.3 5.5 10.4 5.2 4.3 1.7 1.9 2.7 0.5 5.1 10.0 5.0 1.2 12.2 8.2 3.3 2.9 5.1 3.6 4.2 2.5 12.7 6.4 184.5 3.1 45.4 9.4 3.0 0.0 9.3 1.0 0.9 5.3 1.9 1.8 10.3 1.4 6.1 3.1 10.1 10.1 3.4 2.7 12.0 6.4 1.1 3.7 3.3 4.7 9.1 6.6 4.3 6.6 4.0 3.2 5.4 0.1 1.9 3.3 8.6 5.0 0.6 GPBP1L1 SP192 ENSG00000159592 "GC-rich promoter binding protein 1 like 1" Q9HC44 1 45627304-45688113 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028593 Approved Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028593: AB_10602906" "unprognostic (1.39e-1)" "unprognostic (8.41e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (6.35e-2)" "unprognostic (1.97e-3)" "unprognostic (2.42e-3)" "unprognostic (9.79e-2)" "unprognostic (3.91e-2)" "unprognostic (1.94e-3)" "unprognostic (1.12e-2)" "unprognostic (4.11e-1)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (4.51e-1)" "unprognostic (7.56e-3)" "unprognostic (6.13e-2)" 28.7 26.7 25.2 31.0 29.4 49.3 40.9 27.3 28.0 35.0 26.1 57.3 54.0 35.6 37.6 45.0 36.2 30.3 41.7 23.6 27.1 47.0 66.3 39.2 39.9 27.7 28.3 30.6 39.3 41.7 25.5 34.1 28.2 35.8 61.2 27.4 42.4 36.1 46.2 47.2 56.7 36.3 26.8 36.9 42.6 57.9 27.4 54.7 48.7 54.9 49.5 35.6 36.7 32.8 41.1 24.7 42.1 44.9 48.4 47.1 57.5 31.9 52.2 44.8 56.1 25.2 44.8 56.3 40.5 43.7 46.9 42.0 46.6 47.8 56.3 64.4 33.4 73.7 28.9 39.2 66.7 74.2 65.1 34.6 102.0 35.3 99.4 60.2 57.7 71.0 63.7 48.7 51.6 22.0 66.2 65.8 60.4 54.8 27.7 43.0 55.1 41.9 51.5 40.2 51.9 34.7 52.6 76.6 83.5 81.6 35.1 86.2 49.8 32.0 33.6 35.2 48.9 47.2 46.9 41.3 34.0 60.6 34.5 24.0 21.6 40.3 21.6 27.3 22.9 16.5 20.9 21.1 23.0 14.1 22.6 22.4 22.6 26.6 30.6 13.1 26.4 21.1 25.2 29.4 27.3 28.0 23.6 27.1 27.7 28.3 28.2 26.8 27.4 32.8 43.3 60.9 24.4 54.5 45.1 64.9 41.2 28.3 59.2 23.5 51.3 33.5 46.9 41.5 34.3 60.7 35.5 26.2 47.5 96.8 50.9 33.0 23.4 38.1 32.2 38.6 38.3 62.1 48.5 38.9 33.7 25.4 44.9 47.5 59.6 24.3 37.5 81.3 25.0 37.0 49.0 67.2 32.6 49.9 51.6 17.6 20.5 46.1 23.2 70.3 41.3 18.2 45.3 50.8 93.8 51.2 57.0 21.4 36.6 62.8 75.5 58.7 33.0 32.9 19.7 22.4 42.0 78.9 75.3 71.7 67.8 45.4 47.1 27.7 68.6 78.2 GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 226.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 199.8;Syncytiotrophoblasts: 102.7;Urothelial cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 9500000 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" 36.8 78.5 42.8 9.0 37.0 0.4 30.7 25.3 64.4 44.5 3.1 36.7 5.8 37.1 9.3 88.4 30.8 8.5 145.2 41.7 28.5 47.6 35.7 21.9 1.4 29.2 30.4 45.1 25.8 9.8 55.7 29.0 26.3 67.8 3.5 5.0 35.2 22.5 134.2 226.0 17.4 16.4 11.3 15.6 23.0 48.7 46.0 9.1 15.7 35.3 6.6 35.1 62.3 24.8 69.0 92.9 21.6 56.7 64.3 61.5 87.3 161.5 78.8 18.3 21.2 33.3 74.9 1.8 21.8 172.0 100.1 186.0 11.7 114.7 3.8 33.3 9.8 0.1 80.7 41.7 92.2 1.6 6.2 54.3 73.4 41.2 21.3 38.1 9.7 3.4 0.4 3.3 47.5 36.0 1.3 0.6 33.7 7.7 20.5 12.3 98.2 16.1 15.0 109.6 21.5 14.4 105.7 91.9 10.1 19.3 29.1 7.0 45.6 97.3 162.3 46.9 67.8 0.7 0.4 0.8 69.4 1.7 111.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.8 37.0 25.3 64.4 41.7 28.5 29.2 30.4 26.3 11.3 46.0 24.8 1.2 16.0 6.1 45.7 0.7 45.9 69.6 62.2 56.3 22.4 8.3 18.2 53.2 21.5 34.0 25.8 2.1 73.7 0.3 3.7 7.9 27.8 0.9 6.2 24.7 2.8 0.0 0.0 53.0 10.8 199.8 21.0 1.5 8.9 4.5 49.4 11.0 26.3 9.1 25.2 45.0 7.0 16.2 0.6 7.7 3.8 19.0 1.2 35.6 5.6 1.6 24.9 1.0 18.6 8.9 17.6 0.9 7.5 0.9 67.0 0.5 2.3 30.2 6.4 26.3 33.9 38.2 2.2 9.9 44.8 46.2 102.7 1.9 14.5 3.6 110.5 GPC5 ENSG00000179399 "Glypican 5" P78333 13 91398621-92873682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.1;kidney: 7.3;testis: 6.1" "Cell type enriched" "Detected in some" 20 "Astrocytes: 3868.1" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "CACO-2: 49.9;HeLa: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040152, HPA044081" Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA040152: AB_2676863, HPA044081: AB_2678801" "unprognostic (4.99e-3)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (9.93e-5)" "prognostic unfavorable (4.37e-4)" "unprognostic (4.46e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-2)" "unprognostic (9.49e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-5)" "unprognostic (2.19e-2)" "unprognostic (1.82e-6)" "unprognostic (3.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.11e-1)" "unprognostic (6.69e-3)" 0.1 1.6 10.3 0.3 18.1 0.1 0.0 6.7 9.6 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.1 0.5 1.1 8.4 12.1 7.3 1.3 3.2 0.2 18.2 13.4 0.4 0.1 0.0 1.7 0.4 20.5 0.1 0.5 0.5 0.1 0.4 0.0 0.1 0.1 0.1 5.7 0.0 0.1 6.1 23.1 0.1 1.1 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.9 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 27.4 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.3 0.6 0.0 1.7 0.0 0.8 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 3.4 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.0 0.0 10.3 18.1 6.7 9.6 8.4 12.1 18.2 13.4 20.5 5.7 23.1 4.9 0.0 0.0 2.7 3868.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.1 0.0 0.1 64.6 0.0 1.6 0.0 0.0 0.1 0.0 0.0 116.6 0.0 0.0 0.4 0.0 0.1 0.0 7.9 0.0 0.0 0.1 0.0 190.6 0.1 0.0 0.0 0.4 1.0 0.3 0.1 0.0 118.0 0.6 0.0 0.0 127.2 20.9 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.7 0.8 0.3 0.1 0.0 0.0 0.1 0.1 0.5 0.0 0.1 GPKOW "GPATC5, GPATCH5, Mos2, Spp2, T54" ENSG00000068394 "G-patch domain and KOW motifs" Q92917 X 49113407-49123735 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000287, HPA001894" Enhanced Enhanced Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA000287: AB_1079015, HPA001894: AB_1079014" "unprognostic (3.34e-2)" "unprognostic (9.54e-3)" "unprognostic (8.95e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (2.03e-3)" "unprognostic (1.02e-1)" "unprognostic (9.29e-2)" "unprognostic (7.96e-2)" "unprognostic (4.32e-1)" "unprognostic (7.08e-2)" "unprognostic (1.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.73e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-2)" 17.6 15.9 21.5 11.7 22.6 16.1 16.4 22.7 21.8 14.7 14.0 17.0 14.3 16.9 11.8 14.7 15.1 10.3 18.6 19.8 21.2 15.5 14.5 13.8 14.9 24.2 23.6 13.6 12.1 19.0 17.2 13.8 23.9 12.7 12.6 11.9 13.8 16.5 34.8 20.4 14.1 13.8 22.4 15.4 15.5 7.2 25.2 17.7 13.4 25.4 14.4 16.2 14.2 24.4 36.5 38.1 24.9 20.9 21.6 18.6 27.0 23.1 25.9 36.0 38.0 27.9 35.5 15.2 17.4 28.6 36.8 25.2 27.9 27.3 23.4 32.2 29.8 15.8 31.4 19.9 25.8 18.9 32.1 20.4 34.3 28.8 29.2 21.1 27.4 30.0 19.8 23.1 23.8 59.5 26.0 31.5 17.6 19.5 30.0 32.2 27.4 41.5 18.5 45.8 20.8 24.1 26.9 25.2 25.4 26.1 48.5 24.5 30.7 20.7 31.2 30.4 22.1 35.4 26.1 20.7 26.7 31.1 32.7 26.2 22.3 28.9 37.2 31.4 30.3 20.5 28.6 27.8 22.6 34.8 24.3 22.4 17.3 25.0 35.9 20.8 31.1 20.2 21.5 22.6 22.7 21.8 19.8 21.2 24.2 23.6 23.9 22.4 25.2 24.4 10.9 19.2 11.0 7.2 10.5 8.0 14.1 21.8 4.6 14.8 6.4 5.5 13.1 21.5 19.1 7.3 4.2 28.4 16.3 16.2 15.6 26.2 1.1 15.6 10.0 13.4 7.8 22.5 2.8 25.2 20.5 11.7 14.3 10.6 11.4 10.4 11.7 14.5 16.7 5.0 2.8 12.1 18.3 10.9 9.3 1.7 15.5 8.7 5.4 2.8 13.2 20.9 28.8 2.0 3.9 25.6 23.2 15.1 9.4 9.4 19.5 20.5 12.7 13.4 39.5 12.9 13.0 9.9 18.4 6.1 9.9 43.8 16.7 10.6 11.0 12.8 GPR12 "GPCR21, PPP1R84" ENSG00000132975 "G protein-coupled receptor 12" P47775 13 26755200-26760786 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;retina: 8.4;skin 1: 5.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 9.7;Excitatory neurons: 9.5;Hofbauer cells: 17.6;Horizontal cells: 33.7;Inhibitory neurons: 15.7;Skeletal myocytes: 8.1" "Group enriched" "Detected in some" 7 "breast cancer: 0.5;glioma: 0.8;ovarian cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050972 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA050972: AB_2681295" "unprognostic (2.37e-2)" "unprognostic (9.64e-3)" "unprognostic (3.75e-1)" "unprognostic (3.30e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-2)" "unprognostic (1.42e-1)" "unprognostic (7.35e-2)" "unprognostic (5.53e-2)" "unprognostic (3.83e-2)" "unprognostic (2.40e-1)" 0.2 0.0 3.7 0.0 14.3 0.1 1.4 7.6 10.7 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.2 8.1 1.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.7 0.4 0.2 0.0 0.0 8.4 2.9 0.0 0.1 5.4 0.1 0.1 0.1 0.1 0.0 0.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 14.3 7.6 10.7 8.1 1.0 0.0 3.3 0.2 0.1 4.3 2.9 0.4 0.0 0.0 1.6 0.0 0.1 0.2 0.0 0.0 2.8 2.7 2.8 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.7 9.7 0.0 9.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 17.6 33.7 15.7 0.0 0.0 0.0 0.0 0.5 0.0 0.2 3.6 0.0 0.0 1.9 0.0 5.0 0.9 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 3.5 0.0 8.1 0.2 0.1 0.3 0.0 0.1 0.3 0.2 0.0 0.0 0.2 GPR143 OA1 ENSG00000101850 "G protein-coupled receptor 143" P51810 X 9725346-9786297 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.2;choroid plexus: 14.4" "Group enriched" "Detected in many" 8 "Cytotrophoblasts: 40.6;Melanocytes: 126.3" "Cancer enriched" "Detected in all" 9 "melanoma: 84.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.1" "Lineage enriched" "Detected in single" 19 "granulocytes: 3.1" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 159.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA003648 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA003648: AB_2667028" "unprognostic (4.60e-2)" "prognostic favorable (8.73e-4)" "unprognostic (7.43e-3)" "unprognostic (5.41e-2)" "unprognostic (4.62e-3)" "unprognostic (2.00e-2)" "unprognostic (3.05e-1)" "unprognostic (2.64e-3)" "unprognostic (3.78e-1)" "unprognostic (5.89e-2)" "unprognostic (8.18e-2)" "unprognostic (8.40e-2)" "prognostic favorable (2.45e-5)" "unprognostic (2.75e-1)" "unprognostic (2.07e-1)" "unprognostic (8.76e-2)" "unprognostic (1.59e-2)" 0.6 1.1 10.6 0.1 13.0 0.0 1.7 11.8 11.5 2.0 14.4 1.4 0.5 3.2 5.3 2.4 2.8 0.9 0.1 10.8 13.1 4.6 1.7 1.0 0.5 12.6 14.2 3.3 1.2 2.9 2.7 6.1 12.3 2.6 1.4 0.9 3.3 4.4 0.0 8.9 0.5 1.0 11.4 0.0 0.7 0.8 13.1 1.8 3.2 0.0 1.6 1.1 1.1 12.2 1.9 0.4 4.6 0.2 0.0 0.0 3.7 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.2 0.0 0.4 0.1 0.2 1.1 0.1 0.1 0.3 0.0 0.2 0.6 2.3 0.0 3.4 0.1 1.6 0.0 0.0 24.2 6.7 0.0 0.0 0.0 0.0 12.1 0.0 0.1 11.1 0.0 0.1 0.0 0.1 0.1 22.2 3.2 0.9 0.0 0.3 0.0 159.6 10.8 1.9 0.0 4.6 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.4 3.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 10.6 13.0 11.8 11.5 10.8 13.1 12.6 14.2 12.3 11.4 13.1 12.2 0.1 0.0 0.0 9.8 0.2 5.5 1.3 1.8 2.2 0.5 2.1 1.7 0.9 0.0 4.9 7.3 0.0 40.6 0.0 0.8 1.9 4.9 0.2 1.7 1.6 1.5 0.0 0.0 0.6 0.6 2.1 1.0 0.0 1.3 0.0 1.8 2.9 0.3 4.8 0.0 0.3 0.8 2.0 0.0 1.6 1.8 1.8 0.1 126.3 1.0 0.0 1.2 0.0 0.5 0.6 1.2 0.2 6.4 0.0 1.8 0.2 5.0 3.2 0.2 0.0 0.0 0.7 0.2 1.3 4.2 0.6 10.1 0.7 1.0 2.0 1.8 GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079543-168137667 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 41.5;smooth muscle: 27.6" "Cell type enriched" "Detected in many" 8 "Horizontal cells: 158.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 44.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Uncertain Nucleoplasm,Nucleoli Yes No "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Nucleoli "HPA015576: AB_1849283, HPA072047: AB_2686484" "unprognostic (1.45e-1)" "unprognostic (3.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (6.84e-2)" "unprognostic (3.24e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.04e-2)" "unprognostic (5.45e-2)" "unprognostic (1.31e-2)" "unprognostic (5.57e-6)" "unprognostic (3.93e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" 3.5 1.1 3.8 5.3 2.8 0.2 2.7 3.3 4.0 6.7 1.1 8.4 1.5 41.5 3.6 9.8 10.7 5.6 3.1 3.8 2.4 1.4 0.4 4.2 0.9 3.7 9.4 7.3 11.7 5.4 1.7 2.2 3.8 9.5 3.2 2.1 1.8 11.8 1.0 2.1 3.3 27.6 2.8 2.0 2.9 1.7 4.1 2.0 1.7 1.9 1.3 4.6 5.4 2.7 11.7 7.1 28.0 18.1 6.6 11.7 0.0 11.1 11.9 9.2 9.7 44.9 1.8 0.0 6.0 16.6 17.2 33.9 6.9 10.7 5.3 4.4 8.8 4.2 5.8 0.1 2.8 1.2 2.8 4.2 6.9 7.9 12.7 21.3 18.7 3.6 3.9 0.1 14.2 1.0 1.3 0.2 11.5 19.4 11.0 3.4 12.1 0.0 4.9 3.1 5.7 24.6 12.0 0.4 32.2 10.6 6.3 1.4 25.4 18.9 9.7 25.6 12.7 0.0 0.0 0.0 5.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 2.8 3.3 4.0 3.8 2.4 3.7 9.4 3.8 2.8 4.1 2.7 5.8 3.2 1.1 13.7 0.1 2.2 5.7 2.5 5.2 2.2 2.2 4.2 3.6 0.0 1.4 0.0 0.0 0.5 0.0 2.8 0.0 4.1 0.4 1.3 19.4 9.1 0.0 0.0 10.8 8.0 0.4 12.3 1.1 1.8 0.0 15.3 8.9 0.1 0.8 158.2 10.9 1.5 0.0 2.5 6.3 0.9 7.5 2.0 1.8 3.7 1.1 3.2 0.0 9.5 0.4 2.6 2.4 17.0 0.0 10.9 0.0 0.1 1.1 2.1 19.7 8.8 15.1 0.3 3.3 2.7 1.4 0.4 1.0 0.7 2.5 2.7 GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.6" "Cell type enhanced" "Detected in some" "Adipocytes: 26.7;Endothelial cells: 26.4;Hepatic stellate cells: 24.7;Sertoli cells: 6.6;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HUVEC TERT2: 18.7;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" 40.6 6.9 7.0 3.3 6.2 0.5 22.1 6.0 8.8 4.9 6.2 4.2 0.9 7.4 0.7 2.6 6.0 3.3 23.8 5.6 5.9 24.6 3.6 28.6 0.9 8.0 7.5 3.5 3.7 1.4 5.9 4.0 8.6 5.8 0.7 0.9 2.9 0.9 5.7 2.9 5.1 2.5 6.5 4.1 5.6 1.7 10.7 0.5 18.2 2.5 0.6 7.0 4.9 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.7 0.7 1.1 0.0 0.1 0.0 2.0 0.1 0.0 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.5 0.0 0.8 0.0 0.0 0.3 0.3 0.0 18.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 31.3 0.1 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 6.2 6.0 8.8 5.6 5.9 8.0 7.5 8.6 6.5 10.7 6.3 26.7 0.0 0.5 0.7 0.1 2.4 0.2 0.0 1.2 0.1 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.1 0.3 26.4 0.0 0.0 0.1 0.0 0.0 1.5 2.0 0.2 0.0 0.0 24.7 0.1 0.3 0.0 0.2 0.0 0.0 1.2 1.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 6.6 0.6 16.8 0.0 0.2 0.1 1.3 0.0 0.1 0.3 0.0 0.3 GPR55 ENSG00000135898 "G protein-coupled receptor 55" Q9Y2T6 2 230907318-230961066 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;lymphoid tissue: 4.4;testis: 4.7" "Cell type enhanced" "Detected in some" "B-cells: 2.1;Enteroendocrine cells: 1.8;Excitatory neurons: 2.3;Langerhans cells: 3.1;Plasma cells: 2.4;T-cells: 4.2" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 4 "basal ganglia: 4.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "Karpas-707: 32.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.88e-4)" "unprognostic (2.60e-2)" "unprognostic (2.27e-1)" "unprognostic (4.24e-3)" "unprognostic (5.93e-2)" "unprognostic (1.12e-4)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (4.37e-2)" "unprognostic (3.18e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-2)" "unprognostic (4.26e-1)" 0.2 0.0 0.3 1.8 4.6 0.2 0.5 0.0 0.5 0.1 0.0 0.8 1.3 0.1 0.0 0.5 0.1 0.5 0.1 0.3 0.4 0.0 0.2 0.5 2.9 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 1.0 0.2 0.0 0.4 2.2 0.1 0.0 4.1 0.7 4.7 1.0 1.9 0.1 0.0 4.4 0.9 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 2.1 0.0 0.6 0.0 0.0 0.0 0.0 6.5 0.0 0.2 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.8 32.0 0.0 0.0 0.2 0.9 0.7 0.0 1.0 0.1 0.0 3.1 0.0 0.0 1.2 0.0 0.0 0.0 6.0 0.0 0.0 2.3 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.1 1.9 0.1 0.9 0.2 0.9 0.1 0.7 1.3 1.7 0.3 4.6 0.0 0.5 0.3 0.4 0.1 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.3 2.1 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.8 0.0 0.0 0.1 1.8 0.0 2.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.4 0.0 0.1 0.0 0.1 1.4 0.0 0.3 3.1 0.9 0.0 1.2 0.0 1.0 0.9 0.0 1.0 0.5 0.1 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.2 0.1 0.2 0.1 GPRASP1 "GASP, GASP1" ENSG00000198932 "G protein-coupled receptor associated sorting protein 1" Q5JY77 X 102651092-102659083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 42.6;Cardiomyocytes: 28.6;Cone photoreceptor cells: 37.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 4.5;REH: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000161, HPA031061" Approved Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA000161: AB_2247872, HPA031061: AB_2673718" "unprognostic (3.92e-3)" "unprognostic (1.10e-1)" "unprognostic (2.07e-4)" "unprognostic (1.42e-1)" "unprognostic (3.32e-2)" "unprognostic (1.71e-3)" "unprognostic (3.57e-1)" "unprognostic (2.33e-2)" "unprognostic (1.58e-1)" "unprognostic (2.82e-1)" "prognostic favorable (1.77e-5)" "unprognostic (3.34e-1)" "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.23e-2)" 8.6 22.6 25.1 5.4 23.9 3.8 9.9 19.8 31.2 32.4 2.7 23.3 2.4 25.5 10.7 4.4 26.7 7.6 17.7 22.8 33.2 10.3 2.9 7.2 9.4 16.6 17.8 53.4 5.6 17.3 43.5 2.9 18.6 20.4 4.5 29.9 8.7 17.7 6.1 5.2 12.4 15.3 12.8 11.3 9.6 5.3 23.6 6.8 26.1 4.2 7.6 18.6 16.9 20.2 0.2 0.5 1.7 1.1 1.7 1.7 1.0 1.8 0.1 2.7 4.5 0.2 0.3 0.0 0.4 3.8 0.3 0.5 0.5 0.1 3.9 0.0 0.2 0.1 0.6 0.5 1.4 0.2 0.2 2.2 0.7 3.3 0.3 0.4 0.2 1.8 0.3 0.1 4.3 0.4 3.7 0.1 1.2 0.3 0.6 5.6 1.7 0.0 0.2 0.4 1.7 2.7 0.6 0.2 0.5 1.4 0.2 0.9 0.5 0.8 1.0 0.5 0.3 0.3 0.5 0.0 0.4 0.2 1.1 0.0 0.0 0.0 0.5 0.0 1.3 0.2 1.1 0.4 0.0 0.7 2.3 2.3 0.0 0.1 0.0 0.3 0.8 0.5 25.1 23.9 19.8 31.2 22.8 33.2 16.6 17.8 18.6 12.8 23.6 20.2 5.1 0.0 3.6 0.0 4.4 3.6 4.1 0.8 1.8 42.6 1.8 3.0 28.6 1.5 3.5 5.5 37.5 0.4 3.5 0.1 0.0 0.2 0.3 0.6 6.5 7.3 6.0 0.4 0.0 0.2 0.2 9.9 1.1 0.7 2.5 13.9 7.1 0.7 0.3 6.7 0.0 0.7 0.0 0.3 2.0 1.7 15.2 1.3 1.8 0.0 0.5 12.9 3.1 0.0 0.0 0.6 0.1 15.4 2.2 3.8 0.4 1.7 1.2 18.8 6.6 16.9 8.5 7.0 2.4 0.4 0.9 0.1 7.3 6.5 0.8 1.6 GPRIN2 "KIAA0514, MGC15171" ENSG00000204175 "G protein regulated inducer of neurite outgrowth 2" O60269 10 46549044-46555530 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.5;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Distal enterocytes: 30.4;Exocrine glandular cells: 20.2;Intestinal goblet cells: 30.8;Late spermatids: 20.6;Proximal enterocytes: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 10.2;A549: 13.1;SiHa: 3.7;SK-BR-3: 12.0" "Low region specificity" "Detected in many" "HPA038129, HPA070760" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA038129: AB_2675846, HPA070760: " "unprognostic (1.00e-2)" "unprognostic (1.91e-1)" "unprognostic (1.77e-2)" "prognostic unfavorable (8.60e-8)" "unprognostic (5.77e-2)" "prognostic favorable (3.47e-4)" "unprognostic (2.23e-1)" "unprognostic (2.67e-2)" "unprognostic (2.54e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "unprognostic (1.98e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.67e-3)" 0.1 0.0 1.7 0.6 1.6 0.0 0.9 5.9 2.1 0.9 0.4 6.2 3.6 0.0 0.0 4.4 0.3 0.2 0.0 0.6 6.7 5.7 0.3 10.5 0.0 5.5 4.9 0.1 5.7 2.1 4.2 0.0 5.7 1.9 3.4 0.1 2.8 1.1 0.1 17.4 8.0 0.1 1.8 0.0 5.1 3.0 9.7 0.0 3.4 0.0 0.5 0.6 2.0 1.0 10.2 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.2 0.0 0.7 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.0 1.7 0.3 0.3 0.1 3.7 12.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 5.9 2.1 0.6 6.7 5.5 4.9 5.7 1.8 9.7 1.0 0.0 19.2 3.7 0.0 0.0 1.7 2.8 1.9 2.8 0.3 1.4 1.0 0.2 7.2 2.1 3.7 0.0 0.0 0.0 30.4 0.0 11.3 9.3 0.0 0.0 0.1 6.6 0.0 0.7 20.2 0.0 0.1 3.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.9 30.8 0.0 0.0 0.3 20.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.6 13.1 0.4 0.0 2.1 21.7 4.0 1.8 0.1 0.0 0.0 0.2 2.9 0.8 2.4 6.1 0.0 0.1 0.0 7.3 1.3 GPSM3 "AGS4, C6orf9, G18, G18.1a, G18.1b, G18.2, NG1" ENSG00000213654 "G protein signaling modulator 3" Q9Y4H4 6 32190766-32195523 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 160.8;lymphoid tissue: 229.3" "Cell type enhanced" "Detected in many" "B-cells: 261.0;dendritic cells: 238.9;Hofbauer cells: 278.3;Kupffer cells: 397.2;Langerhans cells: 209.3;Macrophages: 268.2;monocytes: 375.1;NK-cells: 352.2;T-cells: 256.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 226.9;NB-4: 115.8;THP-1: 107.1;U-937: 76.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 73000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.93e-2)" "unprognostic (2.51e-2)" "unprognostic (2.02e-2)" "prognostic favorable (5.98e-4)" "unprognostic (3.55e-1)" "unprognostic (3.07e-2)" "unprognostic (3.66e-1)" "unprognostic (6.61e-2)" "unprognostic (4.48e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (6.92e-9)" "unprognostic (2.01e-2)" "unprognostic (1.69e-2)" "unprognostic (5.47e-2)" "unprognostic (5.87e-2)" 28.7 11.8 11.1 96.8 10.3 160.8 15.5 10.8 14.1 8.9 10.5 17.9 14.4 6.8 9.1 9.4 13.9 24.8 14.9 10.5 13.4 15.9 14.5 62.9 139.9 15.6 13.6 5.3 6.1 1.8 7.6 22.2 13.9 13.8 15.8 0.3 11.8 5.5 3.7 9.1 67.7 10.0 12.3 229.3 17.5 5.6 14.6 83.0 11.6 5.6 100.8 32.8 9.1 14.4 1.0 0.0 1.6 0.6 0.1 0.2 1.5 1.3 17.0 5.6 8.8 0.2 5.2 41.1 7.8 6.7 0.5 0.9 0.1 7.2 3.1 53.8 0.1 59.5 0.0 1.2 9.6 0.0 226.9 2.0 0.0 1.9 5.9 1.2 25.8 25.7 11.4 47.9 1.6 0.0 23.6 115.8 0.0 0.0 0.5 24.5 0.0 38.4 1.4 0.0 0.6 0.1 0.0 0.6 8.7 2.1 1.1 107.1 22.6 3.0 3.1 0.0 1.5 1.1 0.9 25.9 0.9 76.3 15.5 44.1 55.8 194.3 35.5 73.3 35.7 52.8 45.5 44.7 57.9 41.9 38.5 42.7 244.9 27.1 71.5 24.3 34.7 53.2 11.1 10.3 10.8 14.1 10.5 13.4 15.6 13.6 13.9 12.3 14.6 14.4 12.8 0.0 2.2 1.0 261.0 11.2 12.9 11.5 4.0 0.2 7.7 9.1 0.5 2.8 7.3 3.7 0.0 3.4 238.9 2.2 0.0 7.9 6.5 1.1 1.0 19.5 1.2 46.3 0.1 5.2 5.1 7.1 8.6 0.9 57.8 0.5 28.2 4.4 278.3 0.0 0.3 6.5 30.5 397.2 209.3 12.1 1.2 268.2 44.4 4.7 375.1 0.5 352.2 0.0 0.3 20.5 34.2 0.0 76.4 5.8 0.5 2.4 5.5 0.5 6.6 1.3 9.4 0.8 3.9 1.4 8.5 6.3 256.1 7.8 3.7 24.6 GPX7 "FLJ14777, GPX6, NPGPx" ENSG00000116157 "Glutathione peroxidase 7" Q96SL4 1 52602371-52609051 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 68.6;HEL: 63.9;REH: 76.4;RPMI-8226: 130.0;THP-1: 101.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 25: RPMI-8226 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (7.43e-3)" "unprognostic (3.18e-1)" "unprognostic (5.64e-2)" "unprognostic (6.12e-3)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (8.18e-2)" "unprognostic (4.17e-1)" "unprognostic (2.48e-3)" "prognostic unfavorable (2.26e-5)" "unprognostic (1.14e-2)" "unprognostic (9.24e-2)" "unprognostic (3.08e-2)" "unprognostic (5.44e-2)" 8.4 7.9 4.8 12.4 5.0 18.3 11.9 5.2 5.4 11.6 9.3 9.4 3.3 13.1 7.3 4.3 9.1 13.4 10.8 4.6 5.9 6.9 5.3 6.8 16.5 5.2 5.1 8.9 11.5 8.5 12.5 29.3 5.0 8.7 5.5 1.7 5.9 9.7 12.1 5.0 6.0 10.8 5.0 8.1 5.0 5.5 5.0 15.9 17.1 11.5 14.0 12.4 6.9 4.9 0.1 0.0 18.1 33.9 6.6 19.1 0.1 12.5 0.7 14.8 15.3 12.2 0.0 0.1 9.8 68.6 0.0 0.0 29.0 0.0 8.1 0.0 0.2 63.9 3.6 11.3 23.9 0.0 0.0 44.4 0.0 2.5 0.0 0.0 22.9 0.4 0.0 0.0 28.2 0.0 3.3 33.5 31.5 0.0 0.0 76.4 0.0 130.0 1.3 0.0 13.7 27.0 33.3 0.0 21.9 3.0 0.0 101.1 1.4 0.0 3.7 3.8 0.1 0.1 0.0 47.9 0.0 0.2 11.3 0.2 1.7 5.4 22.6 0.4 31.8 32.0 34.6 27.1 5.4 35.2 44.5 29.0 0.9 31.6 0.2 73.7 27.6 21.4 4.8 5.0 5.2 5.4 4.6 5.9 5.2 5.1 5.0 5.0 5.0 4.9 8.4 3.2 5.5 1.0 16.1 2.2 9.0 8.3 1.2 1.0 7.1 13.6 3.9 12.8 6.5 3.7 0.0 22.8 9.2 0.2 5.9 11.1 6.9 8.2 43.7 12.4 1.2 6.7 1.6 15.6 19.8 30.5 0.5 6.5 1.3 25.8 15.4 3.8 12.3 5.0 2.7 1.2 2.0 1.9 0.7 6.6 15.2 6.0 7.2 4.7 5.0 8.3 9.2 4.5 2.0 4.7 0.7 13.5 25.2 5.7 0.0 3.0 7.0 0.6 13.1 13.3 14.5 10.8 12.1 1.9 3.3 15.6 10.9 19.3 0.6 4.9 GRAMD1A "FLJ90346, KIAA1533" ENSG00000089351 "GRAM domain containing 1A" Q96CP6 19 34994784-35026471 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008852, HPA012570" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Cytosol "HPA008852: AB_1079203, HPA012570: AB_2112577" "unprognostic (3.09e-2)" "unprognostic (4.62e-2)" "unprognostic (8.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (3.42e-3)" "unprognostic (5.96e-2)" "unprognostic (4.54e-1)" "unprognostic (5.70e-2)" "unprognostic (1.07e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.95e-12)" "unprognostic (2.04e-1)" "unprognostic (4.40e-1)" "unprognostic (2.90e-2)" "unprognostic (4.36e-2)" 37.9 36.9 17.8 28.0 15.9 23.9 31.1 16.4 24.5 33.2 17.5 30.1 15.1 32.5 5.3 11.6 36.2 16.5 30.3 17.4 18.5 27.4 21.2 58.1 28.8 21.8 20.7 38.4 80.8 17.8 29.2 16.8 21.5 32.6 8.4 5.1 55.6 17.0 47.8 14.5 23.3 18.9 18.2 42.1 35.8 16.6 21.5 18.7 25.4 18.9 12.8 35.7 20.1 17.1 17.3 106.0 21.3 41.5 23.9 27.5 19.6 21.6 27.5 21.8 21.6 39.8 11.9 10.8 41.2 25.2 19.3 9.5 22.2 31.9 8.2 48.9 47.3 24.6 25.5 36.8 48.3 21.7 41.1 46.5 19.9 16.1 26.7 36.6 71.5 54.1 31.8 5.7 16.0 13.2 46.5 23.6 38.6 28.4 12.7 47.1 6.9 10.7 24.8 2.5 30.8 64.4 20.0 12.7 33.7 18.4 19.4 20.6 38.9 34.9 22.3 8.0 29.6 8.8 26.3 22.4 23.5 19.6 27.0 23.1 5.7 5.4 3.5 9.6 7.3 0.6 4.6 2.7 5.1 1.2 3.5 5.4 12.7 5.7 19.9 1.7 4.1 3.8 17.8 15.9 16.4 24.5 17.4 18.5 21.8 20.7 21.5 18.2 21.5 17.1 51.0 22.4 37.3 28.1 23.6 20.8 64.4 15.1 18.2 15.8 22.0 18.7 12.3 0.0 16.1 16.5 16.7 13.1 32.3 3.5 3.9 36.8 1.4 15.3 19.9 63.2 39.4 20.4 8.9 57.8 35.8 25.6 10.7 16.5 9.5 39.5 66.4 5.6 53.8 8.4 12.1 15.0 14.2 39.4 81.6 3.0 25.7 37.7 33.8 15.0 146.0 23.1 19.6 12.5 15.1 41.2 9.6 25.2 40.4 68.6 1.4 15.1 11.5 14.9 13.1 15.4 26.0 1.2 5.7 3.4 15.3 33.1 48.1 50.6 19.7 51.9 GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 143.0;Late spermatids: 212.6;Oligodendrocytes: 124.7;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.0;eosinophil: 3.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 10.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: AB_2674057" "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" 27.6 26.0 29.5 6.5 33.6 10.0 25.0 25.2 32.5 18.2 28.5 27.2 17.2 19.8 10.3 9.5 18.8 21.6 34.8 26.5 40.2 29.3 32.1 20.6 6.0 31.5 41.8 14.2 94.3 10.5 24.3 14.7 40.2 20.1 6.4 83.5 16.5 15.0 57.4 9.1 13.3 16.1 21.6 36.8 17.6 18.1 48.2 2.8 27.8 76.0 4.0 31.0 15.9 33.5 0.3 32.5 51.6 21.1 23.5 17.8 27.6 13.1 11.3 24.9 29.7 19.8 0.4 0.7 22.6 16.7 71.0 3.1 53.5 13.9 12.2 0.4 21.6 56.7 32.6 14.4 49.8 36.0 84.1 46.4 21.0 38.6 37.4 23.9 62.7 3.9 109.5 0.6 18.7 4.0 6.4 48.0 56.9 27.2 55.4 16.8 0.0 0.3 16.0 13.1 22.7 0.2 1.6 8.1 68.7 33.0 27.7 71.6 78.7 21.8 29.6 45.4 50.4 2.1 0.7 0.4 68.9 32.2 75.2 10.0 0.1 3.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 29.5 33.6 25.2 32.5 26.5 40.2 31.5 41.8 40.2 21.6 48.2 33.5 46.3 6.4 8.3 3.9 1.2 7.5 5.3 9.4 7.4 12.1 14.8 9.0 13.5 47.1 5.2 5.5 87.6 4.5 0.3 6.9 1.9 18.3 143.0 5.3 12.4 45.2 0.0 19.0 64.8 24.4 16.5 15.4 5.6 9.7 0.0 0.8 53.2 26.8 1.6 5.0 55.0 2.8 6.1 9.7 5.5 212.6 1.8 4.0 7.2 40.3 0.8 21.8 0.0 41.7 124.7 36.4 3.0 0.4 0.6 22.2 11.2 22.2 2.3 81.9 0.0 9.2 10.9 1.9 16.2 1.2 4.3 2.6 1.5 0.9 3.8 7.0 GRB14 ENSG00000115290 "Growth factor receptor bound protein 14" Q14449 2 164492417-164621482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 12.6;tongue: 20.3" "Group enriched" "Detected in many" 4 "Distal tubular cells: 92.0;Granulosa cells: 272.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.5" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.5;HUVEC TERT2: 9.6;RPTEC TERT1: 9.1;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022294, HPA035052, HPA035053" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022294: , HPA035052: , HPA035053: AB_2674432" "unprognostic (2.60e-1)" "unprognostic (6.34e-2)" "unprognostic (1.74e-2)" "unprognostic (6.75e-2)" "unprognostic (7.47e-2)" "unprognostic (8.33e-5)" "unprognostic (5.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (8.33e-3)" "unprognostic (2.71e-1)" "unprognostic (1.89e-3)" "unprognostic (7.10e-2)" "unprognostic (5.19e-2)" "unprognostic (9.27e-2)" 0.7 3.0 0.0 0.3 0.4 0.0 0.3 0.0 0.6 0.1 0.1 0.9 0.9 0.2 5.4 1.2 0.1 0.1 2.7 1.3 0.1 6.6 12.6 0.4 0.0 0.3 0.2 2.0 4.7 0.0 0.3 1.7 0.0 0.3 0.3 0.4 0.3 0.3 2.4 0.2 0.2 0.4 0.0 0.2 0.2 2.6 0.3 0.0 0.9 20.3 0.0 0.0 0.1 0.0 0.8 5.5 0.3 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 2.5 0.5 0.0 2.9 0.0 0.9 0.3 0.8 1.2 0.3 0.0 4.1 0.0 0.3 1.3 0.1 0.0 0.0 0.3 0.8 1.8 0.0 1.6 9.6 0.0 0.0 0.0 1.5 2.1 0.0 0.0 1.9 0.2 1.2 0.0 0.0 0.1 9.1 0.4 3.1 0.3 0.0 0.3 0.0 1.1 0.7 0.0 11.8 0.1 1.2 0.0 0.1 0.4 0.1 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.6 1.3 0.1 0.3 0.2 0.0 0.0 0.3 0.0 4.5 0.0 5.4 0.7 0.1 0.1 0.3 0.0 0.0 1.3 1.6 1.4 17.7 22.8 0.0 16.5 0.0 0.2 1.3 0.3 92.0 13.5 1.5 0.6 0.2 3.0 0.0 0.0 24.5 3.3 0.2 2.4 0.0 1.9 0.0 272.4 1.1 40.4 0.0 0.0 6.2 2.6 0.0 1.0 0.3 4.4 9.3 3.2 19.6 1.9 1.0 0.3 0.0 3.5 2.3 4.0 0.0 17.3 0.0 0.8 0.3 14.7 0.0 0.8 13.1 0.8 10.9 0.7 6.4 0.1 0.0 0.1 0.2 30.4 1.6 0.2 GRHL2 "BOM, DFNA28, FLJ13782, TFCP2L3" ENSG00000083307 "Grainyhead like transcription factor 2" Q6ISB3 8 101492439-101669726 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Respiratory ciliated cells: 28.8;Squamous epithelial cells: 27.1;Suprabasal keratinocytes: 26.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 39.3;CACO-2: 28.0;HaCaT: 46.3;hTCEpi: 35.5;MCF7: 32.7;OE19: 37.9;RT4: 68.9;T-47d: 79.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004820, HPA062839" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA004820: AB_1857928, HPA062839: AB_2684878" "prognostic unfavorable (6.43e-4)" "unprognostic (2.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.68e-1)" "unprognostic (4.79e-2)" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (2.61e-2)" "unprognostic (8.29e-4)" "unprognostic (4.54e-3)" "unprognostic (2.64e-1)" "unprognostic (1.08e-1)" "unprognostic (1.03e-2)" 0.1 0.0 0.0 1.0 0.0 0.0 12.3 0.0 0.3 6.9 0.0 8.0 4.0 1.7 16.1 20.4 8.5 3.3 0.0 0.0 0.0 6.3 0.4 5.6 0.0 0.0 0.0 0.0 11.1 9.3 0.8 6.7 0.0 23.2 9.2 0.0 14.8 7.2 0.0 28.6 4.3 0.4 0.0 0.1 9.8 0.3 0.0 2.9 10.2 0.0 4.6 7.7 10.4 0.0 39.3 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 28.0 18.9 0.0 0.0 0.1 0.0 46.3 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.3 0.2 37.9 0.0 0.0 0.0 0.1 0.0 68.9 1.9 0.0 0.0 15.0 0.0 4.4 79.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.1 13.0 0.3 0.0 24.3 10.5 7.6 20.5 0.0 14.4 6.1 0.7 17.2 20.8 11.0 0.0 14.0 0.2 10.3 5.9 7.5 2.4 20.0 1.5 0.8 1.2 0.0 0.8 5.5 7.1 0.8 15.3 20.7 0.0 0.0 0.0 0.0 1.4 0.0 1.3 9.8 2.0 0.0 1.1 9.3 0.0 0.3 1.8 0.0 0.6 0.0 0.0 2.0 0.5 8.8 8.5 0.0 1.3 9.3 5.7 0.1 28.8 0.0 0.0 0.5 1.0 0.1 0.0 27.1 26.0 19.8 0.3 0.1 11.0 6.3 GRIA2 "GluA2, GLUR2, GLURB" ENSG00000120251 "Glutamate ionotropic receptor AMPA type subunit 2" P42262 4 157204182-157366075 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;retina: 29.0" "Cell type enhanced" "Detected in some" "Astrocytes: 335.0;Bipolar cells: 252.7;Excitatory neurons: 1090.5;Inhibitory neurons: 725.5;Oligodendrocyte precursor cells: 1106.8;Oligodendrocytes: 324.7" "Group enriched" "Detected in some" 10 "breast cancer: 2.7;endometrial cancer: 2.6;glioma: 6.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 16.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008441 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA008441: AB_1078983" "unprognostic (1.36e-1)" "unprognostic (9.60e-3)" "unprognostic (4.15e-2)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (8.70e-2)" "unprognostic (3.87e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-3)" "unprognostic (7.40e-2)" "unprognostic (2.91e-5)" "unprognostic (2.42e-1)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (6.55e-2)" 0.3 6.9 32.8 0.2 60.2 0.0 1.1 11.4 77.4 9.2 0.0 0.2 0.1 17.0 11.5 0.1 11.0 0.0 0.1 78.4 11.3 0.4 0.0 0.2 0.0 0.0 7.4 0.6 1.4 0.0 21.7 0.1 0.0 0.8 0.1 29.0 4.1 2.3 0.2 1.6 0.1 6.2 1.4 0.2 1.2 1.4 37.3 0.1 0.0 0.6 0.0 0.1 0.4 43.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 2.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.9 0.1 0.0 0.0 0.5 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 60.2 11.4 77.4 78.4 11.3 0.0 7.4 0.0 1.4 37.3 43.2 0.0 0.0 0.0 335.0 0.0 0.0 0.0 0.0 0.0 252.7 2.1 1.0 2.3 0.0 0.0 0.0 43.8 0.0 0.1 0.0 0.0 0.0 0.1 1.7 1.1 0.3 0.0 0.0 1090.5 0.0 0.0 0.2 0.0 2.7 0.0 0.1 0.0 0.0 0.1 138.0 725.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 58.1 0.0 4.2 0.0 1106.8 324.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.5 3.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 GRID2IP ENSG00000215045 "Grid2 interacting protein" A4D2P6 7 6497462-6551436 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "brain: 31.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.8;Inhibitory neurons: 2.9;Oligodendrocyte precursor cells: 4.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "thalamus: 31.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "REH: 3.6" "Group enriched" "Detected in many" 5 "cerebellum: 22.4;thalamus: 7.2" "Low region specificity" "Detected in all" HPA045381 Approved "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA045381: AB_10962495" "unprognostic (1.77e-1)" "unprognostic (2.64e-1)" "unprognostic (3.39e-4)" "unprognostic (1.19e-3)" "unprognostic (5.52e-2)" "unprognostic (2.50e-2)" "unprognostic (2.82e-1)" "unprognostic (2.37e-2)" "unprognostic (1.92e-3)" "unprognostic (2.06e-3)" "unprognostic (1.64e-1)" "unprognostic (3.40e-2)" "unprognostic (3.38e-2)" "unprognostic (5.54e-2)" "unprognostic (8.08e-2)" "unprognostic (1.87e-1)" "unprognostic (3.17e-1)" 0.0 0.4 6.7 0.1 6.2 0.2 0.2 10.7 1.4 0.1 0.0 0.3 0.4 0.1 0.0 0.3 0.2 0.1 0.1 0.1 7.9 0.2 0.0 0.2 0.1 2.4 9.8 0.1 0.5 0.5 0.9 0.0 1.9 0.5 0.1 0.5 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.3 0.4 0.3 31.9 0.2 0.3 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.3 0.0 3.6 0.1 0.1 0.0 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 6.2 10.7 1.4 0.1 7.9 2.4 9.8 1.9 0.0 31.9 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.6 0.1 0.2 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.5 0.1 0.0 0.1 0.0 0.4 2.8 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 4.5 1.3 0.1 0.0 0.0 0.3 0.2 0.4 0.1 0.0 1.0 0.0 0.0 0.1 0.8 0.2 1.2 0.0 0.0 0.1 0.9 0.1 0.2 GRIN1 "GluN1, NMDAR1" ENSG00000176884 "Glutamate ionotropic receptor NMDA type subunit 1" Q05586 9 137139154-137168756 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "brain: 186.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 132.6;Inhibitory neurons: 134.4" "Cancer enhanced" "Detected in some" "glioma: 1.9;prostate cancer: 1.8" "Region enriched" "Detected in many" 4 "cerebral cortex: 186.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.4;REH: 1.9;RPMI-8226: 2.5;SCLC-21H: 5.2;SH-SY5Y: 3.1;T-47d: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067773 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA067773: " "unprognostic (3.58e-2)" "unprognostic (4.51e-1)" "unprognostic (2.68e-2)" "unprognostic (5.48e-4)" "unprognostic (5.20e-2)" "unprognostic (1.25e-1)" "unprognostic (2.34e-2)" "unprognostic (2.81e-2)" "unprognostic (6.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.21e-3)" "unprognostic (4.47e-2)" "unprognostic (1.44e-1)" "unprognostic (3.56e-3)" "unprognostic (4.72e-2)" 0.0 0.1 15.7 0.2 46.4 0.0 0.2 0.0 186.7 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.0 0.0 0.1 35.9 0.0 0.0 0.0 0.1 0.1 1.3 19.5 0.0 0.1 0.2 0.7 0.0 3.8 0.7 0.0 3.7 1.2 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.1 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 1.4 0.0 1.9 0.0 2.5 0.0 0.0 5.2 3.1 0.1 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 46.4 0.0 186.7 35.9 0.0 1.3 19.5 3.8 0.0 0.0 35.6 0.0 0.0 0.0 8.5 0.0 0.0 0.3 0.1 0.0 28.0 1.2 0.9 2.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 1.9 0.2 0.1 0.2 1.8 0.0 132.6 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 1.7 134.4 1.8 0.0 0.0 0.0 0.6 0.0 0.2 0.0 9.4 2.0 1.7 0.0 10.1 7.6 0.2 0.1 0.0 0.0 0.7 0.5 0.1 0.3 7.8 0.0 0.0 0.1 0.5 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 GRIP1 ENSG00000155974 "Glutamate receptor interacting protein 1" Q9Y3R0 12 66347431-67069162 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 16.4" "Cell type enriched" "Detected in many" 7 "Inhibitory neurons: 2829.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "myeloid DC: 4.9" "Lineage enriched" "Detected in many" 5 "dendritic cells: 4.9" "Cell line enhanced" "Detected in many" "BEWO: 44.4;HaCaT: 48.7;REH: 30.7;RT4: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038856 Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA038856: AB_10673297" "unprognostic (6.25e-3)" "unprognostic (6.41e-2)" "unprognostic (1.52e-2)" "unprognostic (8.25e-2)" "unprognostic (1.50e-1)" "unprognostic (5.12e-2)" "unprognostic (2.42e-1)" "unprognostic (4.21e-3)" "unprognostic (4.25e-1)" "unprognostic (1.60e-2)" "unprognostic (1.00e-2)" "unprognostic (4.14e-1)" "unprognostic (2.82e-3)" "unprognostic (7.44e-2)" "unprognostic (1.32e-1)" "unprognostic (7.27e-4)" "unprognostic (8.57e-3)" 0.5 4.3 8.5 2.7 6.6 0.5 3.0 0.0 14.2 1.2 0.0 3.1 1.1 3.5 4.7 7.3 4.2 1.6 2.7 3.9 12.4 3.3 0.3 0.8 0.7 0.7 7.6 1.2 2.0 16.4 3.3 8.2 2.2 4.6 1.7 4.8 6.0 9.3 1.0 9.8 1.9 2.8 0.0 2.6 0.8 6.2 3.0 0.7 5.0 0.6 1.3 2.6 2.0 3.7 11.1 10.1 17.7 2.1 0.0 0.0 44.4 3.2 0.0 5.4 2.5 0.3 3.3 1.4 4.2 0.0 9.5 48.7 4.9 3.3 2.4 0.0 12.0 0.0 0.1 0.3 0.0 1.2 0.1 0.0 8.0 0.0 0.8 8.3 0.0 8.0 0.0 0.1 0.0 4.0 0.4 0.4 16.1 1.4 3.6 30.7 0.1 0.6 5.6 31.0 10.8 1.4 14.8 7.1 1.4 11.3 8.7 1.8 0.0 0.0 12.7 0.1 9.0 1.5 0.3 1.0 12.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.9 0.1 0.1 0.2 0.0 1.0 0.0 0.3 0.0 0.1 8.5 6.6 0.0 14.2 3.9 12.4 0.7 7.6 2.2 0.0 3.0 3.7 0.1 0.0 1.1 74.7 0.1 13.3 2.3 2.9 2.2 5.5 4.1 2.4 3.4 1.5 1.7 7.3 0.0 7.8 0.7 0.3 0.0 2.2 38.5 8.1 2.2 0.4 1.8 0.0 390.2 1.5 4.3 1.1 0.0 13.7 0.0 2.3 0.0 0.0 1.0 47.1 2829.7 0.7 0.0 2.4 1.6 34.0 0.6 2.1 7.2 20.6 1.0 0.5 0.0 158.3 44.4 1.9 0.5 0.7 0.1 3.8 0.2 0.4 1.1 1.8 0.0 1.0 0.6 0.3 1.2 2.3 17.8 16.6 0.8 1.2 0.7 3.1 GRTP1 "FLJ22474, TBC1D6" ENSG00000139835 "Growth hormone regulated TBC protein 1" Q5TC63 13 113324163-113364148 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 83.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.3;Proximal enterocytes: 70.2;Rod photoreceptor cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 60.4;T-47d: 54.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046201 Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA046201: AB_2679584" "unprognostic (5.31e-2)" "unprognostic (2.27e-3)" "unprognostic (1.94e-1)" "unprognostic (1.89e-1)" "unprognostic (4.42e-2)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (6.05e-2)" "unprognostic (1.30e-2)" "unprognostic (3.07e-3)" "prognostic favorable (1.50e-5)" "unprognostic (4.41e-3)" "unprognostic (5.55e-2)" "unprognostic (8.56e-2)" "unprognostic (4.50e-3)" 4.4 14.2 2.6 3.2 2.6 2.9 7.9 3.5 5.3 14.3 5.8 24.8 46.0 8.6 3.5 21.6 10.5 6.1 2.6 2.7 2.0 19.3 83.9 4.5 1.6 2.8 2.8 12.8 9.8 8.3 2.8 2.9 2.5 18.3 13.3 20.9 14.5 4.9 10.0 25.9 38.8 3.0 2.8 7.8 13.2 9.5 2.7 1.6 4.0 1.3 2.5 10.6 17.0 3.2 10.1 3.8 7.5 12.9 1.2 1.9 23.6 1.9 0.0 0.5 0.2 21.9 23.2 0.6 1.5 0.6 4.7 15.5 6.6 1.9 0.0 0.5 8.7 13.5 11.2 21.9 2.1 1.1 4.8 0.6 2.9 1.6 0.2 1.0 0.0 1.3 8.2 0.7 0.0 20.5 0.2 1.9 21.2 60.4 2.9 1.1 0.3 0.4 1.7 12.3 0.6 6.6 0.4 11.3 2.7 8.9 54.6 1.3 1.0 0.4 2.8 1.8 0.7 3.8 4.3 1.5 8.1 3.0 4.4 0.6 0.4 0.3 0.2 0.2 0.2 0.2 0.3 0.2 0.1 0.3 0.5 0.2 2.2 0.3 0.5 0.3 0.1 0.7 2.6 2.6 3.5 5.3 2.7 2.0 2.8 2.8 2.5 2.8 2.7 3.2 1.1 0.0 6.0 11.1 0.8 21.7 24.0 23.4 14.2 5.8 12.7 8.6 1.2 30.0 15.9 3.7 81.3 28.8 0.7 51.8 23.5 10.0 0.4 6.2 4.8 3.0 3.6 3.8 0.5 9.2 9.2 4.0 14.3 8.8 0.0 18.3 5.7 30.1 1.7 3.3 0.5 28.2 16.2 0.8 1.9 0.8 8.1 2.3 1.8 1.0 2.6 13.7 0.0 1.0 1.0 9.6 43.3 8.6 0.1 11.0 70.2 45.8 9.6 69.6 0.0 5.9 5.3 0.2 8.8 18.2 23.7 25.3 1.2 2.7 40.1 23.8 GSC ENSG00000133937 "Goosecoid homeobox" P56915 14 94768223-94770113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.8;breast: 6.8" "Cell type enhanced" "Detected in some" "Adipocytes: 3.5;Breast myoepithelial cells: 2.2;Ductal cells: 3.0;Exocrine glandular cells: 2.4;Fibroblasts: 9.2;Langerhans cells: 2.3;Skeletal myocytes: 2.6;Smooth muscle cells: 4.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "hypothalamus: 1.4" "Immune cell enriched" "Detected in single" 8 "gdT-cell: 3.6" "Lineage enriched" "Detected in single" 18 "T-cells: 3.6" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HEK 293: 2.0;MCF7: 3.2;REH: 3.3;SH-SY5Y: 3.5;T-47d: 2.5;U-251 MG: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB079923, CAB079924" Supported "Nucleoplasm,Nuclear speckles,Actin filaments" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear speckles" "Actin filaments" "CAB079923: , CAB079924: " "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (3.15e-2)" "unprognostic (5.11e-2)" "unprognostic (2.49e-1)" "unprognostic (3.70e-3)" "unprognostic (1.82e-3)" "unprognostic (3.87e-2)" "unprognostic (3.41e-1)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (2.28e-1)" "unprognostic (5.18e-10)" "unprognostic (4.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" 3.8 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.4 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.5 0.0 1.4 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.0 0.0 0.7 0.0 0.0 0.9 0.5 1.2 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 1.6 2.2 0.1 0.3 0.2 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.6 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.0 0.1 0.3 0.1 0.4 0.0 0.0 0.0 2.4 0.0 9.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 2.6 4.6 0.0 1.2 0.0 0.9 0.0 0.4 0.0 0.0 0.1 GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 58.9" "Group enriched" "Detected in some" 5 "Collecting duct cells: 3.7;Hofbauer cells: 5.0;Kupffer cells: 5.6;Macrophages: 2.6;Suprabasal keratinocytes: 2.7;Theca cells: 2.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HBEC3-KT: 4.1;hTCEpi: 2.7;hTERT-HME1: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 44000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: AB_1850378, HPA064826: AB_2685361" "unprognostic (1.32e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" "unprognostic (2.90e-2)" "unprognostic (1.06e-2)" "unprognostic (9.86e-2)" "unprognostic (7.45e-2)" "unprognostic (3.63e-2)" "unprognostic (3.79e-2)" 3.4 0.7 0.2 0.9 0.2 0.4 3.5 0.4 0.4 0.8 0.2 0.7 0.6 0.4 6.6 3.2 0.3 0.8 0.3 0.3 0.2 0.3 0.3 0.4 0.7 0.4 0.0 0.1 0.3 1.3 0.1 1.6 0.4 0.1 1.2 0.0 0.8 0.0 0.4 58.9 0.5 0.6 0.0 0.2 0.3 0.3 0.4 0.5 0.1 0.1 3.4 1.1 1.5 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.5 0.4 0.2 0.0 0.1 0.8 0.0 2.7 0.5 5.4 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.9 0.1 0.1 2.2 0.0 2.6 0.0 1.3 0.8 0.1 0.1 0.6 0.9 0.7 0.1 0.1 0.2 0.5 0.5 0.2 0.2 0.4 0.4 0.3 0.2 0.4 0.0 0.4 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 3.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 5.0 0.0 0.1 0.7 0.0 5.6 0.6 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 0.2 2.8 0.0 0.0 GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 46.5;Basal squamous epithelial cells: 37.5;Squamous epithelial cells: 29.5;Suprabasal keratinocytes: 53.1" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 3.7;hTCEpi: 1.8;HUVEC TERT2: 2.0;TIME: 5.8" "Low region specificity" "Detected in many" "HPA023670, HPA024767, HPA026317" Supported Approved Mitochondria NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria "HPA023670: AB_1854006, HPA024767: AB_1854007, HPA026317: AB_1854008" "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.4 0.0 0.0 0.0 0.0 0.1 33.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 5.4 0.0 0.0 25.5 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.4 11.4 0.1 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.0 1.0 0.0 46.5 0.9 7.4 37.5 0.0 1.5 0.9 3.6 0.0 9.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.1 0.0 3.9 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.1 29.5 53.1 0.0 0.1 0.0 0.0 2.8 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GSTA3 ENSG00000174156 "Glutathione S-transferase alpha 3" Q16772 6 52896639-52909698 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 67.3;fallopian tube: 65.4;placenta: 22.7;skin 1: 26.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 194.9;Syncytiotrophoblasts: 515.3;Theca cells: 91.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.5;testis cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.4" "HPA004342, HPA048934, HPA053817" Approved Supported Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA004342: AB_1078987, HPA048934: AB_2680563, HPA053817: AB_2630367" "unprognostic (7.51e-2)" "unprognostic (7.06e-3)" "unprognostic (3.10e-1)" "unprognostic (5.53e-2)" "unprognostic (4.38e-3)" "unprognostic (2.86e-3)" "unprognostic (1.81e-1)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (9.35e-2)" 0.0 67.3 0.0 0.1 0.1 0.0 1.8 0.0 0.0 1.1 0.5 0.0 0.3 0.8 0.8 0.0 65.4 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.5 0.9 0.1 2.9 0.0 22.7 0.0 0.1 0.0 0.0 0.3 0.2 0.0 26.0 0.4 0.1 0.0 0.0 2.4 11.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.3 0.1 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 6.2 0.0 0.0 194.9 0.0 0.0 0.0 0.0 1.3 47.0 0.5 0.5 0.0 0.0 0.0 0.0 7.5 1.1 0.0 0.7 1.3 7.4 0.0 0.4 15.7 0.0 0.0 0.0 2.0 0.0 0.4 2.1 1.5 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 24.8 0.0 0.0 0.0 0.8 0.5 0.5 0.0 9.8 515.3 0.1 91.3 0.0 0.0 GSTO2 ENSG00000065621 "Glutathione S-transferase omega 2" Q9H4Y5 10 104268873-104304950 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 133.1;Early spermatids: 314.6;Late spermatids: 442.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 16.9;CAPAN-2: 17.1;hTCEpi: 16.2;hTERT-HME1: 18.3;OE19: 22.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA048141 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "HPA048141: AB_2680281" "unprognostic (5.77e-2)" "unprognostic (6.69e-2)" "unprognostic (7.15e-2)" "unprognostic (1.80e-1)" "unprognostic (2.48e-1)" "unprognostic (3.11e-2)" "unprognostic (3.12e-1)" "unprognostic (2.15e-1)" "unprognostic (7.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.10e-7)" "unprognostic (4.56e-2)" "unprognostic (3.92e-2)" "unprognostic (1.75e-2)" "unprognostic (3.47e-1)" 0.5 3.5 5.0 0.3 5.7 2.0 5.2 3.4 5.3 4.3 0.4 4.4 2.8 2.2 4.9 11.8 4.3 1.2 0.6 4.4 4.1 14.0 2.8 2.4 0.3 2.2 2.5 5.4 16.7 5.0 14.6 1.0 2.6 8.3 3.1 6.0 7.5 3.2 1.4 14.8 3.5 1.2 1.1 0.5 10.9 35.9 4.3 2.2 7.0 1.3 0.7 3.8 7.5 5.3 10.2 1.4 0.5 0.6 0.6 1.3 1.4 9.6 16.9 4.7 4.9 0.6 17.1 1.6 4.0 0.8 0.5 10.7 0.5 5.3 1.2 1.1 3.2 0.5 3.1 2.4 2.1 0.7 0.7 1.7 16.2 0.3 18.3 1.3 0.8 1.7 1.5 2.9 1.3 12.3 0.1 0.5 1.7 22.1 1.1 0.5 0.7 0.3 4.6 6.5 0.6 1.1 3.3 2.4 2.9 0.8 12.6 0.3 2.4 1.5 5.1 0.6 0.5 2.8 6.4 0.4 1.5 0.8 0.5 0.2 0.1 0.7 0.5 0.2 0.3 0.3 0.5 0.3 0.0 0.5 0.7 0.4 1.7 1.0 0.1 0.3 1.2 0.2 5.0 5.7 3.4 5.3 4.4 4.1 2.2 2.5 2.6 1.1 4.3 5.3 3.6 3.2 21.0 13.1 1.3 34.2 62.1 94.5 50.1 19.0 61.7 78.2 3.0 21.5 46.4 40.5 16.7 14.4 3.8 12.8 133.1 30.6 314.6 26.9 7.6 5.4 54.2 3.6 33.9 63.3 9.9 4.7 31.6 37.6 2.5 3.3 15.7 3.6 1.8 0.0 28.7 34.0 50.8 1.6 3.7 442.8 2.8 2.7 17.8 1.9 2.1 11.1 1.0 24.1 20.1 31.6 29.1 9.8 0.9 25.6 27.1 43.8 31.2 23.0 6.6 3.1 7.4 22.0 8.9 46.0 47.3 6.7 4.3 11.6 40.7 58.0 GSX2 Gsh2 ENSG00000180613 "GS homeobox 2" Q9BZM3 4 54099523-54102498 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "glioma: 2.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (4.48e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (1.89e-1)" 0.0 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.6 0.2 0.2 0.2 0.2 0.4 0.3 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GTF2F2 "BTF4, RAP30, TFIIF" ENSG00000188342 "General transcription factor IIF subunit 2" P13984 13 45120510-45284893 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006912 Supported Supported Nucleoplasm,Microtubules NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Microtubules "HPA006912: AB_1080256" "unprognostic (3.39e-1)" "unprognostic (2.65e-2)" "unprognostic (3.27e-1)" "unprognostic (1.29e-1)" "unprognostic (4.51e-2)" "prognostic unfavorable (1.65e-5)" "unprognostic (3.67e-2)" "unprognostic (3.17e-1)" "unprognostic (3.36e-2)" "unprognostic (2.53e-3)" "unprognostic (2.31e-2)" "unprognostic (4.76e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.53e-3)" "unprognostic (3.94e-2)" "unprognostic (6.44e-3)" 10.9 16.6 12.4 11.0 13.2 18.3 12.9 12.4 14.9 13.5 18.1 18.3 10.4 11.6 15.4 16.5 10.0 8.4 20.0 13.1 13.2 15.0 11.3 9.6 13.4 12.3 13.0 12.1 10.7 14.1 12.9 11.0 12.4 10.7 14.2 9.9 12.2 13.0 25.0 24.9 10.0 12.9 13.5 10.2 11.3 13.3 13.0 14.8 11.4 15.8 14.4 15.5 14.8 15.6 43.2 15.9 29.3 21.8 17.6 25.8 24.3 46.2 30.2 46.1 44.9 26.8 65.7 42.9 25.4 33.9 44.8 46.9 44.3 37.1 66.7 32.6 38.4 50.8 20.7 35.2 28.1 57.0 27.9 21.8 55.9 34.4 57.8 52.0 29.9 32.9 36.6 15.8 125.6 24.2 42.0 65.2 34.8 68.6 38.3 39.0 22.2 24.8 101.4 15.0 15.6 26.0 23.5 22.9 39.8 27.5 18.6 45.9 23.7 38.6 33.1 30.8 79.9 10.0 14.6 42.7 44.9 36.1 41.2 16.2 15.9 29.9 10.3 16.7 12.4 17.3 12.1 12.4 18.8 17.8 13.5 13.5 22.5 18.9 18.9 14.7 14.7 10.1 12.4 13.2 12.4 14.9 13.1 13.2 12.3 13.0 12.4 13.5 13.0 15.6 21.6 41.7 32.1 41.1 36.0 75.1 82.8 80.2 35.9 19.2 27.3 30.2 79.4 10.0 41.6 11.0 4.2 33.0 25.7 29.0 49.0 49.7 93.0 34.9 37.5 27.6 28.2 32.6 23.7 33.6 49.4 28.9 13.7 56.8 39.3 25.6 18.2 21.4 49.1 8.4 35.1 26.4 50.8 27.1 38.2 82.3 24.2 32.0 76.5 36.5 38.2 36.8 27.8 57.8 48.9 48.5 30.3 31.6 30.4 88.3 22.6 42.7 29.4 21.5 6.6 35.6 32.3 68.6 83.9 34.5 72.7 33.8 28.8 33.5 40.7 75.1 GTF3C1 TFIIIC220 ENSG00000077235 "General transcription factor IIIC subunit 1" Q12789 16 27459555-27549913 "Predicted intracellular proteins, Predicted membrane proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 93.8;dendritic cells: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 31.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051617, HPA075900" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Nucleoli" "HPA051617: AB_2681553, HPA075900: " "unprognostic (6.46e-2)" "unprognostic (6.86e-3)" "unprognostic (2.16e-1)" "unprognostic (5.59e-2)" "unprognostic (6.65e-2)" "unprognostic (2.90e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (8.23e-2)" "unprognostic (9.25e-3)" "unprognostic (5.32e-2)" "prognostic favorable (9.56e-4)" "unprognostic (2.10e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.06e-1)" "unprognostic (5.67e-2)" "unprognostic (5.56e-3)" "unprognostic (8.23e-3)" 18.1 28.8 24.2 9.9 24.4 16.6 16.7 21.5 32.6 31.2 40.5 21.2 8.8 26.7 7.8 65.2 24.6 11.5 38.5 24.6 21.8 25.4 21.7 20.3 12.2 20.4 20.8 24.4 35.3 18.6 47.8 11.0 19.6 40.4 9.7 18.3 24.9 12.6 50.2 51.0 18.5 15.5 17.0 21.3 24.7 26.6 22.2 18.6 34.6 20.8 11.2 19.7 35.1 21.7 27.8 60.1 43.3 50.7 37.8 30.4 24.6 29.5 33.0 40.2 34.0 45.0 25.6 30.5 42.3 36.4 30.6 30.3 55.4 37.6 32.9 13.7 53.1 25.2 49.8 63.8 21.3 29.1 32.2 37.5 28.0 49.5 21.8 26.9 40.2 34.6 31.7 24.2 32.0 67.6 32.5 34.8 58.4 15.1 28.3 59.7 53.4 31.4 25.2 28.7 54.4 36.5 29.8 24.9 18.6 34.4 44.8 21.8 43.2 40.2 24.0 25.6 30.7 25.6 24.8 30.2 16.6 31.7 30.2 2.6 3.4 3.5 31.9 3.2 23.0 3.1 3.6 15.8 4.3 2.2 3.7 10.0 2.5 12.2 3.3 6.6 4.0 6.9 24.2 24.4 21.5 32.6 24.6 21.8 20.4 20.8 19.6 17.0 22.2 21.7 16.9 19.2 23.9 29.7 10.8 18.4 7.3 14.3 23.3 45.5 10.6 11.9 27.4 10.0 17.2 12.9 93.8 7.8 86.2 18.4 5.9 11.8 2.8 40.4 37.3 18.0 30.0 7.2 30.2 11.5 4.3 22.5 19.9 22.3 19.0 26.1 13.9 13.7 10.9 26.9 33.9 17.6 18.3 10.3 7.7 4.5 19.3 12.9 3.6 14.0 10.0 15.0 52.5 17.1 23.4 15.8 9.3 15.8 29.6 13.9 10.2 9.0 30.8 35.1 13.1 16.4 15.1 17.2 18.2 34.8 20.6 4.2 32.7 25.7 12.2 6.7 GTF3C4 "KAT12, TFIIIC90" ENSG00000125484 "General transcription factor IIIC subunit 4" Q9UKN8 9 132670035-132694953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transcription "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069369 Supported Nucleoplasm,Mitochondria No No "Cluster 40: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Mitochondria "HPA069369: AB_2686130" "unprognostic (7.02e-2)" "unprognostic (9.01e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-2)" "unprognostic (1.58e-1)" "unprognostic (1.76e-1)" "unprognostic (4.77e-1)" "unprognostic (1.92e-2)" "prognostic favorable (2.99e-4)" "unprognostic (1.65e-1)" "unprognostic (1.23e-1)" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" 4.9 4.4 4.3 4.6 5.0 6.9 8.4 9.2 4.3 7.3 3.6 5.3 3.9 6.6 5.5 6.7 6.6 5.2 5.8 4.5 5.2 6.0 5.3 5.7 5.0 3.4 4.8 10.3 6.1 9.4 3.2 6.4 3.7 6.2 5.4 5.5 7.3 5.7 5.8 9.8 3.6 6.2 3.6 4.5 5.8 8.3 5.6 8.1 9.5 8.0 6.6 5.0 3.8 3.8 15.2 21.7 25.8 22.5 12.3 14.4 20.0 15.1 18.4 19.6 14.4 25.4 10.9 22.7 9.8 18.6 18.1 33.8 39.8 23.6 21.1 15.4 19.1 19.0 28.9 10.8 12.8 28.6 12.4 11.4 17.6 20.4 26.1 11.6 16.8 15.1 32.7 11.4 14.0 24.6 17.8 13.3 33.1 22.2 21.4 17.6 31.1 20.6 14.3 12.5 36.3 24.6 25.9 25.8 15.9 15.8 35.4 12.1 17.8 32.9 18.7 15.1 21.6 4.9 12.3 25.1 13.5 17.8 20.7 0.0 0.3 0.2 0.5 0.3 0.4 0.5 0.4 0.6 0.2 0.4 0.5 0.5 0.3 0.5 0.2 0.5 0.4 0.2 4.3 5.0 9.2 4.3 4.5 5.2 3.4 4.8 3.7 3.6 5.6 3.8 9.9 19.2 11.5 2.3 7.8 30.7 6.9 6.9 21.6 15.5 19.1 14.7 14.6 1.5 6.7 3.7 14.6 7.5 9.0 6.6 7.9 8.3 6.5 21.5 26.2 11.6 13.1 8.2 3.2 6.3 7.5 13.0 8.6 17.7 1.3 17.1 10.0 8.6 6.3 20.2 3.1 8.1 10.2 7.6 9.3 3.7 19.0 6.3 3.6 1.9 7.1 11.9 7.2 1.0 2.1 5.8 7.0 19.2 10.7 11.6 3.8 6.6 16.2 16.9 0.0 18.8 10.9 16.7 13.8 22.1 40.1 6.4 8.8 18.2 9.0 6.4 GTSE1 "B99, GTSE-1" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.2;Extravillous trophoblasts: 31.2;Granulosa cells: 27.1;Spermatocytes: 73.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029457 Approved "Plasma membrane,Centrosome" Yes Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Plasma membrane" "HPA029457: " "unprognostic (1.97e-1)" "unprognostic (3.07e-2)" "unprognostic (1.71e-3)" "unprognostic (2.59e-1)" "unprognostic (7.16e-2)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.90e-10)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.49e-3)" "unprognostic (0.00e+0)" "unprognostic (6.52e-3)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" 0.6 0.6 0.2 5.1 0.2 11.2 0.5 0.5 0.3 0.7 0.2 2.4 4.1 0.8 0.0 3.6 0.2 0.5 0.3 0.2 0.3 0.3 0.4 0.6 9.2 0.4 0.3 0.2 0.2 0.1 0.1 2.6 0.4 0.2 2.6 0.1 0.7 0.1 0.1 2.5 2.9 1.2 0.1 2.4 1.9 7.2 0.5 19.6 0.2 0.2 8.7 1.0 1.2 0.4 59.5 27.6 53.2 42.2 1.1 3.0 25.5 50.3 23.5 71.7 58.8 29.3 21.9 55.7 13.0 19.4 32.8 30.3 48.0 12.7 45.7 33.7 52.0 37.4 38.9 22.8 0.1 67.5 43.8 0.6 1.0 30.9 15.6 7.5 31.2 39.7 29.0 67.8 43.4 33.1 60.9 33.0 37.2 24.2 30.7 59.6 59.7 36.3 11.7 10.7 27.5 37.5 48.1 30.7 21.5 23.8 26.2 25.8 25.1 40.6 75.8 33.4 53.7 38.6 19.7 56.3 25.8 32.2 60.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.4 0.3 0.2 0.2 0.2 0.5 0.3 0.2 0.3 0.4 0.3 0.4 0.1 0.5 0.4 1.1 0.0 0.0 0.7 7.0 2.8 1.1 2.1 0.6 0.7 2.8 3.4 1.6 0.0 0.5 0.0 0.0 19.2 6.8 7.6 0.0 0.9 5.6 2.1 4.7 3.9 1.2 52.2 0.3 0.2 31.2 5.1 16.8 4.3 0.0 27.1 6.4 1.2 19.9 0.0 0.5 9.4 2.0 7.5 4.0 3.9 0.3 4.7 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.8 0.2 0.7 19.1 1.8 0.5 0.5 0.2 0.3 6.6 2.6 5.4 73.6 27.8 11.7 2.6 1.5 5.0 1.2 13.8 1.6 GUCA2B ENSG00000044012 "Guanylate cyclase activator 2B" Q16661 1 42153410-42155820 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 143.1" "Cell type enriched" "Detected in some" 7 "Paneth cells: 18841.5" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 1.4;CACO-2: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Secreted to blood" NA NA 77700 1200000 "Cluster 7: Monocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.59e-2)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (6.22e-2)" "unprognostic (1.86e-1)" 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 89.4 36.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 5.5 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 23.3 0.0 0.0 0.6 0.0 0.1 143.1 0.6 0.0 0.0 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 1098.8 0.0 0.9 1.0 0.0 0.0 0.0 22.8 0.0 0.0 47.9 0.3 0.0 0.0 0.0 22.3 0.0 0.4 3.1 0.1 0.0 0.0 107.2 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 18841.5 0.0 0.0 0.0 2568.9 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 1.3 0.0 55.3 0.9 GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828822-2882820 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 156.3" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Enteroendocrine cells: 20.4;Granulosa cells: 10.2;Hepatocytes: 20.2" "Cancer enhanced" "Detected in all" "melanoma: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 39.1;CACO-2: 30.4;Hep G2: 32.6;NTERA-2: 38.4;SK-MEL-30: 87.6;SuSa: 59.0" "Low region specificity" "Detected in all" "HPA005495, HPA064686" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA005495: AB_1079035, HPA064686: AB_2685323" "unprognostic (4.45e-2)" "unprognostic (4.21e-2)" "unprognostic (6.41e-3)" "unprognostic (8.50e-2)" "unprognostic (2.07e-3)" "unprognostic (5.16e-1)" "unprognostic (1.74e-2)" "unprognostic (1.18e-1)" "unprognostic (7.43e-3)" "unprognostic (6.74e-2)" "prognostic favorable (3.01e-5)" "unprognostic (9.76e-2)" "unprognostic (6.10e-5)" "unprognostic (1.78e-1)" "unprognostic (5.05e-3)" "unprognostic (5.41e-2)" "unprognostic (6.60e-2)" 156.3 2.2 10.3 1.9 10.8 0.2 38.9 18.4 8.8 3.0 8.5 3.9 1.5 6.6 1.0 0.9 5.1 2.2 1.4 11.2 18.9 2.0 18.5 0.5 0.6 29.4 24.5 2.5 5.4 1.0 0.8 2.1 27.3 4.0 2.8 1.4 4.7 6.6 0.3 1.9 2.1 3.7 36.0 0.3 4.5 0.9 13.7 0.4 1.7 0.5 0.3 3.7 2.0 35.4 0.1 11.5 39.1 0.2 20.5 0.0 28.5 2.0 6.3 6.1 8.2 30.4 0.6 0.0 3.1 5.2 6.6 0.0 22.5 0.5 6.8 0.2 6.3 0.1 0.7 32.6 6.7 0.0 8.9 8.1 0.4 1.0 0.0 0.2 0.0 0.0 0.3 0.1 6.6 1.9 0.0 1.0 38.4 0.4 0.2 6.1 13.0 0.0 0.0 0.1 0.0 0.7 0.1 0.3 87.6 59.0 4.1 25.4 0.0 0.0 6.7 3.8 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.3 10.8 18.4 8.8 11.2 18.9 29.4 24.5 27.3 36.0 13.7 35.4 0.3 0.0 0.0 10.7 0.2 0.4 1.1 0.5 0.0 1.2 2.1 0.8 1.2 4.3 0.2 0.0 4.2 6.0 0.0 1.2 5.9 1.0 0.4 3.8 1.0 0.3 20.4 0.0 5.9 4.0 7.9 1.6 4.6 0.7 0.0 10.2 0.0 20.2 1.1 0.0 4.9 1.7 0.0 1.0 0.0 0.5 0.6 0.1 3.6 0.0 0.0 1.6 0.0 0.5 0.1 2.1 0.6 3.0 0.0 1.0 0.4 2.4 1.1 0.1 0.0 0.3 1.2 0.3 1.5 0.0 0.3 2.3 0.0 3.2 3.5 0.7 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102646-55110252 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.1" "Group enriched" "Detected in many" 24 "dendritic cells: 739.3;NK-cells: 1543.8;T-cells: 709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 15 "gdT-cell: 941.4;MAIT T-cell: 926.2;memory CD4 T-cell: 250.0;memory CD8 T-cell: 922.7;naive CD8 T-cell: 494.1;NK-cell: 718.8" "Group enriched" "Detected in all" 42 "NK-cells: 718.8;T-cells: 941.4" "Cell line enhanced" "Detected in some" "HL-60: 4.0;JURKAT: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054134, HPA076751" Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054134: AB_2682395, HPA076751: " "prognostic favorable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favorable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" 5.6 6.0 0.9 16.7 0.9 35.3 7.2 0.9 2.5 7.6 1.2 14.7 29.2 14.7 8.8 4.8 4.6 14.0 4.0 0.8 1.0 3.2 15.2 21.9 68.1 1.6 0.9 4.5 1.0 1.3 1.0 3.1 1.1 3.1 17.8 0.0 7.1 3.0 1.7 1.6 27.6 7.2 1.1 51.1 11.7 2.0 1.1 12.4 2.9 1.3 19.2 13.5 2.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 2.5 3.8 941.4 2.3 926.2 3.4 250.0 922.7 3.1 1.3 48.5 494.1 19.9 718.8 4.0 3.2 33.1 712.7 0.9 0.9 0.9 2.5 0.8 1.0 1.6 0.9 1.1 1.1 1.1 1.1 5.1 3.2 18.1 0.0 12.3 0.4 0.1 0.0 2.8 0.0 2.7 2.4 1.6 5.7 3.1 0.0 0.0 0.4 739.3 1.4 0.0 1.6 0.0 1.7 2.7 2.8 0.0 36.2 0.0 0.0 0.2 7.8 20.4 2.1 7.6 0.0 17.9 2.8 0.3 0.0 0.1 1.5 0.0 25.8 2.6 0.0 0.0 12.3 3.6 0.0 12.6 0.0 1543.8 0.0 0.1 0.0 3.9 0.0 40.8 0.1 2.8 3.3 2.9 0.0 0.0 2.6 2.6 0.0 0.1 1.1 1.4 0.7 709.4 0.0 1.8 0.0 GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.2;lymphoid tissue: 37.1" "Group enriched" "Detected in many" 5 "dendritic cells: 2050.2;NK-cells: 1704.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 6765.2" "Lineage enriched" "Detected in all" 5 "dendritic cells: 6765.2" "Cell line enriched" "Detected in some" 6 "HMC-1: 22.0" "CAB000376, HPA003418" Enhanced "Secreted to blood" NA NA 2170 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favorable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" 8.2 1.7 1.2 17.8 1.3 68.2 2.1 1.2 3.9 1.2 1.4 2.5 2.3 7.1 1.6 3.8 1.5 6.5 1.8 1.2 7.9 1.5 4.1 15.3 37.1 1.5 1.5 0.3 1.0 0.7 0.7 3.3 1.6 1.4 2.2 0.0 2.3 1.4 2.0 0.4 4.4 4.3 1.4 28.9 3.5 0.5 1.8 9.7 1.9 1.5 34.6 18.5 1.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.7 2.8 9.9 3.0 5.3 1338.5 4.0 16.0 7.0 95.2 641.6 6.3 3.1 29.1 607.5 43.1 507.8 6.0 6765.2 2.7 1607.1 1.2 1.3 1.2 3.9 1.2 7.9 1.5 1.5 1.6 1.4 1.8 1.3 4.3 6.4 36.0 0.0 15.9 2.8 0.3 0.0 0.0 0.0 0.9 0.8 1.1 4.3 7.4 0.0 0.0 0.4 2050.2 0.6 0.0 1.6 0.0 0.4 0.5 2.7 0.0 11.8 0.0 0.0 0.1 5.1 9.2 0.5 17.7 0.0 4.2 1.2 0.2 0.0 0.0 0.6 0.0 4.8 9.0 0.2 0.0 27.1 42.7 1.0 11.6 0.0 1704.4 0.0 0.1 0.1 2.3 0.0 86.8 0.2 0.6 3.1 4.4 0.0 0.0 1.3 1.3 0.0 0.1 0.4 4.1 0.3 373.8 0.0 0.6 0.1 GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 99.6" "Group enriched" "Detected in many" 4 "dendritic cells: 136.3;T-cells: 301.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 741.6;NK-cell: 505.5" "Group enriched" "Detected in many" 199 "NK-cells: 505.5;T-cells: 741.6" "Cell line enriched" "Detected in single" 10 "JURKAT: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA063181, HPA065895" Enhanced "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA063181: AB_2684955, HPA065895: " "prognostic favorable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" 3.0 3.9 0.1 19.4 0.1 10.5 4.9 0.1 0.4 4.3 0.3 3.4 1.6 4.0 4.5 3.0 2.0 11.6 2.0 0.1 0.2 1.7 10.7 5.9 99.6 0.5 0.2 2.7 1.0 0.8 0.5 0.5 0.3 3.2 4.6 0.0 4.6 1.0 0.2 0.6 7.3 2.2 0.2 30.4 6.5 1.2 0.3 11.9 2.3 0.3 27.8 8.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.9 1.1 164.3 1.0 741.6 0.5 100.2 457.3 0.5 0.5 4.9 77.4 3.1 505.5 0.9 0.9 7.0 95.5 0.1 0.1 0.1 0.4 0.1 0.2 0.5 0.2 0.3 0.2 0.3 0.3 3.8 3.2 7.0 0.0 10.7 1.5 0.1 0.0 1.8 0.0 1.5 1.7 0.1 2.8 0.6 0.0 0.0 0.0 136.3 0.1 0.0 0.0 1.3 0.8 0.4 0.8 0.0 4.4 0.0 0.0 0.0 1.2 4.1 0.8 2.5 0.0 8.6 1.5 0.2 0.0 0.0 0.0 0.0 10.3 2.5 1.2 0.0 6.4 1.8 0.0 5.1 0.0 29.9 0.0 0.1 0.0 0.0 0.0 45.1 0.1 0.2 0.8 0.0 0.0 0.0 1.8 1.7 0.0 0.3 0.2 0.6 0.3 301.9 0.0 0.0 0.1 H2AX H2AFX ENSG00000188486 "H2A.X variant histone" P16104 11 119093854-119095467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 43.7;Cytotrophoblasts: 83.2;dendritic cells: 34.0;Extravillous trophoblasts: 106.6;Hofbauer cells: 45.8;Syncytiotrophoblasts: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012264, HPA041189, HPA051647" Supported Supported "Nucleoplasm,Nuclear speckles" Yes Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear speckles" "CAB012264: AB_297215, HPA041189: AB_2677357, HPA051647: AB_2681563" "unprognostic (1.44e-1)" "unprognostic (1.96e-1)" "unprognostic (6.46e-2)" "unprognostic (6.41e-2)" "unprognostic (3.07e-1)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (2.32e-3)" "unprognostic (1.93e-1)" "unprognostic (3.07e-3)" "unprognostic (6.78e-2)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.47e-9)" "unprognostic (1.21e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.99e-2)" 13.2 20.7 35.2 12.6 37.8 24.9 8.0 39.0 42.2 13.3 20.6 18.6 13.3 14.0 2.1 43.6 13.1 3.1 13.4 33.7 32.3 17.0 13.9 14.3 16.0 43.9 38.9 18.7 11.6 3.4 24.3 11.0 37.8 15.7 4.3 6.6 11.4 4.7 12.4 18.1 18.8 3.5 38.0 24.0 16.1 15.4 37.8 30.5 10.4 3.6 12.0 11.8 15.7 51.8 132.1 77.9 120.3 72.3 10.9 7.9 126.4 146.0 44.0 80.3 70.4 124.0 55.1 89.7 85.9 34.0 60.5 134.0 57.5 41.7 21.5 133.4 161.0 182.2 20.7 129.8 11.4 90.5 108.9 6.7 9.0 34.2 21.0 13.1 40.7 115.4 149.9 143.1 38.9 335.6 207.8 269.9 87.5 60.0 162.6 200.7 141.6 42.7 37.5 56.3 127.6 152.0 116.0 66.6 20.6 20.6 99.8 68.2 50.9 77.7 204.2 63.8 110.2 38.7 40.8 92.3 17.9 145.2 155.0 3.8 1.3 4.2 1.6 0.6 0.8 0.9 1.7 1.7 1.8 0.8 1.1 1.0 0.6 2.2 0.8 0.8 1.6 1.2 35.2 37.8 39.0 42.2 33.7 32.3 43.9 38.9 37.8 38.0 37.8 51.8 43.7 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 83.2 34.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 106.6 9.4 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 64.2 7.2 0.0 0.0 0.0 H2BC4 "H2B.1, H2B/l, H2BFL, HIST1H2BC" ENSG00000180596 "H2B clustered histone 4" P62807 6 26114873-26123926 "Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 18 "neutrophil: 923.6" "Lineage enriched" "Detected in all" 26 "granulocytes: 923.6" "Cell line enhanced" "Detected in all" "K-562: 39.8;SiHa: 75.8;U-2 OS: 51.9;U-266/70: 42.8;U-266/84: 57.1" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 16: U-266 - Nucleosome" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (8.30e-3)" "unprognostic (2.60e-2)" "unprognostic (2.37e-2)" "unprognostic (9.26e-2)" "unprognostic (3.20e-2)" "unprognostic (5.08e-2)" "unprognostic (4.72e-1)" "unprognostic (6.45e-2)" "unprognostic (9.22e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (9.01e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (5.41e-2)" "unprognostic (7.38e-2)" "unprognostic (2.49e-1)" "unprognostic (6.60e-3)" 4.3 3.4 9.5 6.0 17.4 25.0 6.7 11.4 8.8 9.1 9.9 3.1 3.2 1.2 3.6 14.7 7.1 4.6 3.6 10.5 15.0 5.3 13.1 8.0 2.9 20.3 10.9 2.6 2.6 0.9 5.8 7.2 16.3 21.8 2.3 1.5 7.5 0.9 14.5 6.7 3.0 1.2 21.5 5.1 7.0 6.4 9.4 14.9 3.6 8.0 2.3 3.5 10.2 27.6 7.0 4.0 2.1 2.0 1.9 1.1 2.6 6.8 2.5 4.5 3.7 5.6 4.1 2.7 12.5 2.3 3.3 5.2 2.8 2.8 2.2 6.3 2.3 2.2 6.1 9.6 2.6 3.4 8.4 27.3 1.7 1.9 1.1 2.2 1.8 2.1 39.8 21.1 8.6 8.0 7.5 7.2 2.2 7.4 12.4 3.3 3.0 16.3 7.8 1.7 9.4 3.0 75.8 5.8 2.6 5.5 31.8 3.1 5.6 5.5 51.9 3.4 2.8 42.8 57.1 13.2 2.3 8.6 3.8 52.5 9.3 49.9 9.2 10.5 12.4 19.1 13.3 13.0 6.6 35.1 10.3 7.7 923.6 10.5 10.4 22.0 9.3 19.2 9.5 17.4 11.4 8.8 10.5 15.0 20.3 10.9 16.3 21.5 9.4 27.6 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 5.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 7.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 42.8 0.4 0.0 0.0 0.0 HABP4 "IHABP4, SERBP1L" ENSG00000130956 "Hyaluronan binding protein 4" Q5JVS0 9 96450169-96491336 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.3" "Group enriched" "Detected in many" 10 "Early spermatids: 224.6;Late spermatids: 808.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.9;T-cells: 1.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055969, HPA062366" Enhanced Supported "Nuclear membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" Cytosol "HPA055969: AB_2682991, HPA062366: " "unprognostic (1.67e-1)" "unprognostic (7.99e-2)" "unprognostic (2.12e-3)" "unprognostic (2.40e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (1.36e-2)" "unprognostic (3.63e-2)" "unprognostic (3.49e-1)" "unprognostic (2.42e-2)" "unprognostic (1.75e-3)" "unprognostic (1.36e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.25e-1)" "unprognostic (1.40e-1)" "unprognostic (4.93e-2)" "unprognostic (3.62e-2)" 21.9 12.8 62.7 7.0 70.1 1.8 16.8 55.1 73.3 16.1 40.8 19.2 3.0 13.5 7.0 7.6 13.5 8.8 28.1 62.3 63.9 27.0 7.6 10.8 8.3 66.2 65.4 15.6 6.6 12.9 22.6 3.5 66.1 12.5 4.2 16.0 6.2 11.1 16.8 9.5 10.4 9.7 59.5 7.5 12.5 43.9 61.3 4.6 13.7 13.4 5.3 18.4 13.0 68.9 14.8 16.6 20.6 22.3 44.7 37.9 14.6 19.5 21.8 14.5 15.7 24.9 24.0 7.5 9.4 29.4 45.9 10.6 17.4 3.7 11.6 9.0 10.3 2.9 7.8 42.0 22.7 0.7 3.0 15.5 6.7 16.5 13.0 21.9 10.4 8.4 3.4 21.6 26.4 15.2 0.3 4.6 9.6 20.5 15.8 7.6 17.9 0.3 24.8 6.4 13.0 8.8 10.6 6.2 32.5 15.2 4.5 3.2 17.8 19.8 4.6 36.6 16.8 13.2 14.0 3.3 15.9 5.9 29.8 0.0 0.0 0.0 0.5 0.1 0.5 1.9 1.6 1.3 0.0 1.1 1.1 1.1 0.1 0.4 0.3 0.0 1.3 0.2 62.7 70.1 55.1 73.3 62.3 63.9 66.2 65.4 66.1 59.5 61.3 68.9 22.2 0.0 7.4 27.1 5.9 11.5 10.8 0.9 4.0 22.6 3.8 6.9 11.0 14.3 5.5 18.4 0.0 2.5 5.5 0.9 17.6 4.7 224.6 7.3 9.0 14.6 13.1 0.8 47.4 5.8 7.4 13.3 1.5 8.1 1.3 13.0 15.0 6.3 6.6 23.5 33.2 0.9 4.1 1.3 9.3 808.8 13.7 6.0 17.8 10.3 2.7 22.2 3.1 18.6 37.5 6.3 0.0 23.7 5.1 10.0 1.1 43.7 1.8 15.6 6.6 5.8 26.4 26.8 15.4 0.9 8.0 1.4 13.3 3.0 1.3 6.0 HACL1 "2-HPCL, HPCL, PHYH2" ENSG00000131373 "2-hydroxyacyl-CoA lyase 1" Q9UJ83 3 15560699-15601852 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 117.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 117.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035496, HPA035497, HPA073760" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles Nucleoplasm "HPA035496: AB_10601328, HPA035497: AB_2674653, HPA073760: AB_2686633" "unprognostic (6.64e-3)" "unprognostic (2.82e-2)" "unprognostic (2.24e-3)" "unprognostic (3.82e-1)" "unprognostic (4.08e-2)" "unprognostic (1.77e-1)" "unprognostic (2.96e-2)" "unprognostic (6.31e-2)" "unprognostic (8.27e-3)" "unprognostic (5.23e-2)" "unprognostic (3.30e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.62e-2)" "unprognostic (2.66e-1)" "unprognostic (3.23e-2)" "unprognostic (9.07e-2)" 14.4 12.0 7.5 8.2 7.8 11.6 14.6 10.4 10.5 9.1 7.9 10.0 56.6 8.3 16.6 7.5 10.8 8.8 11.0 7.6 7.0 26.0 51.8 9.7 14.1 7.4 7.2 7.5 15.2 20.0 7.8 7.8 7.0 10.8 12.0 12.2 9.1 9.1 17.6 10.6 27.7 9.5 7.4 11.4 13.2 26.7 6.8 13.9 20.4 10.6 14.5 10.3 6.4 10.0 15.1 28.6 8.2 30.7 13.4 12.4 82.3 14.2 22.0 26.6 26.3 27.3 14.3 14.6 9.7 18.7 10.5 10.4 18.7 25.3 23.8 13.6 36.4 25.4 17.7 24.7 20.3 30.5 23.1 13.7 16.2 37.9 16.6 8.3 31.4 18.3 24.0 21.2 22.9 28.7 14.0 12.6 19.7 19.7 29.7 14.4 21.5 19.6 26.4 20.2 9.6 12.3 22.4 19.0 25.2 12.8 8.5 25.4 22.5 14.1 14.6 17.4 24.7 27.2 50.9 28.5 27.1 26.4 17.2 117.3 16.0 18.3 14.4 20.1 21.2 15.4 15.5 18.0 16.0 21.2 14.8 16.1 3.4 24.1 24.2 10.2 19.8 13.0 7.5 7.8 10.4 10.5 7.6 7.0 7.4 7.2 7.0 7.4 6.8 10.0 12.4 9.6 17.3 34.9 22.1 10.3 12.0 13.5 20.5 19.3 9.1 10.2 6.4 14.3 15.6 11.0 29.2 27.2 15.7 6.1 13.7 16.0 66.6 12.6 6.0 12.3 9.1 8.2 67.4 25.2 18.0 12.0 11.2 5.4 13.3 12.7 8.9 24.3 13.2 13.5 55.8 7.5 10.2 9.3 8.1 56.8 23.3 8.8 12.4 25.3 19.3 24.8 8.2 40.7 38.8 14.5 11.2 15.4 21.4 9.0 41.9 39.7 29.8 38.3 6.6 9.0 11.2 51.1 24.4 8.6 7.1 18.9 19.4 15.1 10.6 7.9 HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035174 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 280.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.4;Proximal enterocytes: 383.0;Proximal tubular cells: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" 143.0 54.1 23.2 20.9 23.8 27.4 74.9 24.6 26.3 37.9 33.5 101.2 84.4 49.8 24.9 34.2 56.2 24.0 175.6 22.9 27.2 140.2 225.5 22.8 22.2 24.7 26.3 54.3 42.1 40.2 18.0 13.7 26.0 35.4 90.8 10.4 55.9 42.4 249.7 28.0 89.1 72.7 26.0 18.0 60.7 27.9 24.9 76.0 37.7 280.3 28.5 34.1 28.7 28.0 32.2 27.9 64.3 46.2 149.2 48.2 27.0 43.1 68.5 49.6 48.9 21.2 60.9 185.0 23.5 38.8 34.6 42.0 85.5 64.5 55.5 49.6 37.2 39.9 50.5 48.9 24.3 88.2 17.0 50.4 34.1 35.1 32.3 41.4 34.4 127.1 53.1 98.7 57.3 58.9 163.6 36.7 29.0 147.8 30.1 113.5 84.3 89.2 54.5 129.4 73.2 43.1 41.1 161.9 45.6 37.0 77.4 70.8 20.6 35.5 18.9 48.5 26.7 52.1 63.3 80.6 47.0 60.2 27.0 0.0 11.1 11.4 17.2 14.2 22.1 31.4 19.5 20.7 36.8 27.1 22.4 22.2 1.2 36.7 20.1 41.7 17.7 16.3 23.2 23.8 24.6 26.3 22.9 27.2 24.7 26.3 26.0 26.0 24.9 28.0 17.3 28.9 33.8 11.1 25.7 15.6 54.2 65.8 41.5 6.9 46.5 56.1 225.6 52.9 48.1 35.0 4.2 41.0 18.3 164.7 160.4 43.3 196.8 41.4 22.6 17.5 32.4 65.6 15.1 32.2 44.7 28.2 52.5 26.1 10.8 63.9 21.0 272.4 116.5 6.7 18.9 93.3 36.7 37.8 11.8 108.5 46.3 25.3 21.4 12.2 15.3 26.8 8.2 9.5 9.9 23.0 100.8 35.3 32.0 33.9 383.0 318.8 70.8 6.8 39.5 21.7 38.2 22.4 20.3 64.0 18.2 17.0 19.6 66.3 194.2 49.1 HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 198.2;skin 1: 61.1" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 129.6" "Cancer enriched" "Detected in some" 11 "liver cancer: 23.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basophil: 56.9;neutrophil: 73.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 73.3" "Cell line enhanced" "Detected in some" "BEWO: 2.2;NB-4: 2.8;THP-1: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038547, HPA038548" Enhanced Approved Cytosol NA NA 280000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA038547: AB_10669541, HPA038548: AB_10673175" "unprognostic (3.39e-1)" "unprognostic (4.46e-2)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (5.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-3)" "unprognostic (1.89e-2)" "unprognostic (3.74e-1)" "unprognostic (4.03e-2)" "unprognostic (2.87e-2)" 1.4 0.3 0.1 2.9 0.1 11.5 2.2 0.1 0.4 0.8 0.1 0.5 0.6 0.4 0.0 1.0 0.7 0.6 0.3 0.1 0.1 0.3 198.2 2.3 0.5 0.1 0.1 0.2 0.9 0.1 3.0 0.4 0.1 0.2 0.4 0.0 0.6 0.1 0.2 61.1 0.8 0.5 0.0 7.6 0.4 0.1 0.1 0.5 0.2 0.6 1.4 0.5 1.4 0.2 0.4 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.4 0.4 0.0 0.6 0.3 0.2 0.1 0.2 0.3 0.0 0.1 0.1 0.0 0.1 2.8 0.9 0.1 0.4 0.2 0.1 0.0 0.1 0.6 0.1 0.3 0.3 0.0 0.0 0.0 0.0 11.4 0.1 0.1 0.1 0.1 0.1 0.4 0.5 0.1 0.0 1.7 0.0 56.9 15.1 2.4 0.0 5.7 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 73.3 0.7 13.6 0.3 0.2 4.4 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.0 1.1 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.7 2.8 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 3.2 2.0 0.4 0.0 9.7 0.2 0.2 0.7 0.1 0.5 15.0 0.0 0.1 2.5 129.6 0.3 0.0 0.1 0.1 0.0 7.7 0.8 0.0 0.0 3.5 0.0 0.0 6.3 0.0 1.0 0.0 0.0 0.0 1.3 0.0 0.4 0.2 1.2 0.7 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 2.8 0.0 0.6 0.0 0.3 0.1 HAO2 "GIG16, HAOX2" ENSG00000116882 "Hydroxyacid oxidase 2" Q9NYQ3 1 119368779-119394130 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "kidney: 303.7;liver: 425.6" "Group enriched" "Detected in some" 7 "Hepatocytes: 256.8;Proximal tubular cells: 450.1" "Group enriched" "Detected in some" 26 "liver cancer: 25.6;renal cancer: 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050355 Uncertain Vesicles,Cytosol NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Vesicles "HPA050355: " "unprognostic (1.13e-1)" "unprognostic (1.68e-2)" "unprognostic (2.07e-1)" "unprognostic (1.00e-1)" "unprognostic (6.22e-2)" "unprognostic (5.33e-3)" "unprognostic (2.80e-2)" "unprognostic (3.27e-1)" "unprognostic (3.15e-1)" "unprognostic (3.17e-1)" "unprognostic (1.41e-1)" "unprognostic (1.73e-1)" "prognostic favorable (4.92e-4)" "unprognostic (9.66e-2)" "unprognostic (1.79e-1)" "unprognostic (2.89e-2)" "unprognostic (5.14e-4)" 0.0 0.6 0.2 0.1 0.6 0.0 0.6 0.1 0.6 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 303.7 425.6 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.1 0.4 0.2 0.1 0.3 23.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.6 0.2 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 11.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.6 0.0 13.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 4.2 256.8 0.1 0.0 0.1 0.0 0.0 6.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 450.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 HASPIN GSG2 ENSG00000177602 "Histone H3 associated protein kinase" Q8TF76 17 3723903-3726699 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 5.3;testis: 7.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;Extravillous trophoblasts: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA027422, HPA030698" Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA027422: AB_10601812, HPA030698: AB_2673575" "unprognostic (1.15e-2)" "unprognostic (2.78e-2)" "unprognostic (7.06e-2)" "unprognostic (2.14e-2)" "unprognostic (8.05e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-4)" "unprognostic (1.57e-2)" "unprognostic (6.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "unprognostic (3.82e-3)" "unprognostic (0.00e+0)" "unprognostic (5.65e-3)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" 0.2 0.1 0.0 1.8 0.2 6.0 0.4 0.0 0.1 0.2 0.2 1.1 1.5 0.2 0.1 1.3 0.3 0.2 0.1 0.0 0.0 0.1 0.1 1.4 4.2 0.1 0.1 0.1 0.2 0.0 0.0 0.6 0.1 0.3 1.0 0.0 0.4 0.0 0.6 0.7 1.8 0.4 0.0 1.7 0.9 7.3 0.2 5.3 0.3 0.1 5.1 0.3 0.5 0.2 11.3 12.2 11.1 12.5 0.7 1.4 9.3 10.2 7.8 19.7 19.3 9.6 4.6 27.7 5.7 5.7 7.9 18.0 20.1 9.9 18.7 0.1 16.7 13.8 9.9 5.8 0.5 8.1 13.7 0.9 0.8 14.9 9.2 2.4 9.1 21.6 12.4 23.7 10.1 5.9 16.4 4.8 9.8 8.7 8.3 16.8 13.9 7.4 3.0 7.8 4.4 6.5 8.9 6.1 3.5 9.6 6.1 7.5 4.7 8.7 9.9 9.8 18.1 4.5 5.4 13.4 5.1 11.5 10.7 0.1 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703357 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8;skin 1: 30.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 84.7;Basal respiratory cells: 52.0;Basal squamous epithelial cells: 120.1;Ionocytes: 87.5;Langerhans cells: 124.0;Suprabasal keratinocytes: 106.1" "Group enriched" "Detected in many" 8 "cervical cancer: 12.6;head and neck cancer: 16.1;lung cancer: 6.4;urothelial cancer: 9.2" "Region enriched" "Detected in some" 5 "cerebral cortex: 5.9" "Immune cell enriched" "Detected in many" 5 "neutrophil: 176.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 176.7" "Cell line enriched" "Detected in some" 6 "HaCaT: 118.4" HPA028660 Approved Supported "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.33e-1)" "unprognostic (3.33e-3)" "unprognostic (7.26e-2)" "unprognostic (2.17e-1)" "unprognostic (1.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.33e-2)" "unprognostic (4.83e-4)" "unprognostic (5.76e-2)" "unprognostic (5.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" 22.2 0.3 0.1 9.8 0.2 22.1 7.6 0.1 5.9 8.9 0.2 0.7 0.9 0.2 0.3 40.8 0.7 0.8 0.9 0.3 0.1 3.9 2.9 11.9 0.6 0.1 0.1 0.1 0.2 5.5 0.3 4.5 1.2 3.4 0.3 0.2 14.2 14.7 0.2 30.2 1.0 0.3 0.1 25.9 1.5 2.7 0.2 10.5 0.5 1.9 10.2 6.9 14.0 0.1 4.5 0.4 0.1 0.1 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 118.4 0.0 7.3 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.3 0.1 3.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 19.5 0.2 0.0 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 38.7 2.5 2.6 0.0 5.3 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 176.7 0.0 23.9 0.0 0.0 1.4 0.1 0.2 0.1 5.9 0.3 0.1 0.1 0.1 1.2 0.1 0.2 0.1 0.4 0.0 4.3 0.0 0.5 94.4 84.7 52.0 120.1 0.5 3.4 1.1 0.1 0.0 40.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 24.9 0.4 0.2 1.2 0.0 0.0 0.0 0.0 26.3 2.4 0.0 0.3 2.5 0.0 0.0 0.0 3.7 0.0 0.0 0.0 87.5 4.1 124.0 2.7 0.0 17.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 8.5 0.1 0.0 0.1 1.4 0.0 0.1 47.2 106.1 2.6 1.5 0.0 0.0 32.5 HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;esophagus: 16.8;lymphoid tissue: 19.6;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 81.1;Basal respiratory cells: 57.3;Basal squamous epithelial cells: 159.4;Langerhans cells: 57.4;Squamous epithelial cells: 66.9;Suprabasal keratinocytes: 106.3;Urothelial cells: 66.1" "Group enriched" "Detected in some" 4 "cervical cancer: 2.1;head and neck cancer: 2.5;lung cancer: 1.0;urothelial cancer: 1.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 4.7" "Group enriched" "Detected in many" 6 "basophil: 58.6;neutrophil: 177.2;non-classical monocyte: 84.4" "Group enriched" "Detected in many" 50 "granulocytes: 177.2;monocytes: 84.4" "Cell line enriched" "Detected in some" 4 "RT4: 37.1" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" 5.6 0.1 0.0 9.2 0.1 27.4 2.3 0.0 4.7 2.5 0.2 0.5 0.2 0.0 0.5 16.8 0.7 0.6 0.7 0.1 0.0 0.9 1.8 8.2 0.4 0.0 0.0 0.1 0.0 3.4 0.2 1.9 0.9 1.5 0.1 0.1 3.4 2.7 0.1 17.4 0.2 0.2 0.0 19.6 0.4 0.1 0.1 4.0 0.4 1.1 7.8 7.1 4.3 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 9.2 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 37.1 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.1 58.6 2.2 0.8 0.0 16.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 177.2 0.0 84.4 0.0 0.0 2.9 0.0 0.1 0.0 4.7 0.1 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 3.2 6.7 0.0 0.7 94.4 81.1 57.3 159.4 0.2 0.7 0.3 0.0 0.0 24.6 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 21.5 1.4 0.0 0.1 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 12.2 10.6 57.4 0.2 0.0 20.1 8.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 14.7 0.0 0.1 2.2 0.2 0.0 0.0 1.4 0.1 0.0 66.9 106.3 13.8 1.0 0.0 0.0 66.1 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 HCN2 "BCNG-2, BCNG2, HAC-1" ENSG00000099822 "Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2" Q9UL51 19 589881-617159 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 146.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 60.4;Horizontal cells: 40.4;Inhibitory neurons: 18.7;Oligodendrocytes: 62.1;Rod photoreceptor cells: 14.9" "Group enriched" "Detected in many" 6 "glioma: 8.7;melanoma: 5.7;renal cancer: 2.8;testis cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 29.9;HeLa: 15.8;MCF7: 28.4;U-138 MG: 20.2;U-87 MG: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (8.69e-2)" "unprognostic (3.97e-3)" "unprognostic (3.31e-4)" "unprognostic (1.44e-1)" "unprognostic (2.44e-1)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" "unprognostic (5.32e-2)" "unprognostic (1.19e-3)" "unprognostic (8.00e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.07e-1)" "unprognostic (1.41e-1)" "unprognostic (5.53e-4)" "unprognostic (9.72e-3)" 0.1 4.2 34.9 0.2 58.1 0.4 0.1 84.7 111.8 0.1 0.0 0.6 0.1 0.1 0.2 1.6 0.0 0.1 11.6 38.2 56.6 1.3 0.2 0.2 0.3 86.6 76.7 0.1 0.3 3.4 12.8 0.1 84.9 0.3 0.0 7.5 0.3 0.1 0.1 0.9 0.4 0.1 38.2 0.4 0.4 3.1 146.0 0.1 0.1 0.0 0.3 0.1 0.4 66.9 0.1 29.9 0.3 1.0 3.1 2.1 1.0 2.1 2.4 0.8 0.2 4.3 0.3 0.0 6.5 2.9 2.1 0.2 0.6 0.1 0.1 5.1 12.6 0.0 15.8 0.4 2.2 0.3 5.6 5.6 0.5 0.2 0.1 0.9 0.1 0.7 1.8 0.2 2.1 28.4 0.1 0.0 1.4 0.7 0.8 0.2 0.1 0.7 0.5 0.9 11.3 5.8 7.3 0.1 2.3 0.5 5.9 1.0 2.8 20.2 3.0 0.4 8.4 0.5 0.4 0.2 41.7 1.4 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 58.1 84.7 111.8 38.2 56.6 86.6 76.7 84.9 38.2 146.0 66.9 0.5 0.0 0.0 2.0 0.6 0.6 0.0 0.0 1.2 60.4 0.7 0.9 4.1 0.0 0.0 0.0 2.1 0.0 1.6 0.3 0.0 0.1 0.1 0.6 0.4 0.9 1.2 2.7 12.8 0.0 0.3 0.2 0.0 1.2 0.0 0.2 0.7 0.1 0.1 40.4 18.7 0.0 0.0 1.3 0.3 0.4 0.0 1.1 0.0 2.8 0.0 2.7 0.0 5.5 62.1 0.1 0.0 0.7 1.4 0.1 0.0 0.3 0.0 14.9 0.0 0.1 0.5 0.1 1.7 4.5 0.6 0.3 1.2 0.1 0.1 0.1 HDGFL3 "Hdgfrp3, HRP-3" ENSG00000166503 "HDGF like 3" Q9Y3E1 15 83112738-83207823 "Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 96.9;Breast glandular cells: 34.3;Endometrial ciliated cells: 34.2;Endometrial stromal cells: 48.4;Granulosa cells: 41.4;Theca cells: 48.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040719 Approved Supported Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA040719: AB_2677097" "unprognostic (1.28e-3)" "unprognostic (1.13e-1)" "unprognostic (3.52e-2)" "unprognostic (3.38e-2)" "unprognostic (1.53e-1)" "unprognostic (2.55e-2)" "unprognostic (1.91e-2)" "unprognostic (2.95e-2)" "unprognostic (2.99e-2)" "unprognostic (4.68e-2)" "unprognostic (1.93e-3)" "unprognostic (3.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.06e-2)" "unprognostic (3.55e-1)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" 6.3 5.9 11.1 2.9 12.0 2.4 5.6 11.6 14.9 5.0 7.2 7.0 1.2 6.0 8.3 3.6 4.7 4.0 5.7 11.8 11.5 4.8 0.8 5.1 2.9 10.5 10.5 5.0 1.7 17.7 6.8 3.0 10.5 4.9 2.6 8.5 2.4 4.6 2.5 2.0 2.9 5.3 11.1 3.4 2.9 9.7 11.8 4.3 6.5 2.5 2.2 5.6 3.8 10.7 7.2 6.2 17.9 9.3 7.4 10.1 5.9 6.7 11.9 7.0 7.3 0.5 13.2 0.1 8.0 1.8 7.5 2.9 19.9 10.3 10.1 33.5 10.2 11.6 3.0 0.1 10.3 0.4 1.8 6.0 8.4 8.0 13.9 10.8 17.0 12.4 9.0 0.3 13.2 7.4 7.1 0.7 13.3 0.0 3.5 0.1 17.4 0.1 10.5 14.6 22.5 17.1 10.1 2.4 8.9 12.9 2.8 1.3 14.7 14.5 10.8 3.0 20.9 2.1 0.8 8.6 6.7 5.5 10.0 0.7 0.3 1.0 0.5 0.1 0.0 0.1 0.1 0.1 0.2 0.2 0.2 0.2 0.8 1.8 0.1 0.2 0.0 0.1 11.1 12.0 11.6 14.9 11.8 11.5 10.5 10.5 10.5 11.1 11.8 10.7 96.9 12.8 17.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 34.3 27.3 0.0 0.0 10.5 20.2 0.0 0.3 14.1 0.0 15.6 21.1 0.0 34.2 48.4 25.8 0.0 0.0 0.0 22.9 0.6 15.4 0.0 25.6 5.1 41.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 23.6 0.0 0.0 3.1 0.0 0.0 0.3 9.5 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.3 3.5 48.1 0.0 0.0 HDX "CXorf43, FLJ30678" ENSG00000165259 "Highly divergent homeobox" Q7Z353 X 84317874-84502479 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.1;Inhibitory neurons: 56.7;Oligodendrocyte precursor cells: 45.8;Oligodendrocytes: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047189 Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA047189: AB_10965463" "unprognostic (7.26e-2)" "unprognostic (3.53e-2)" "unprognostic (1.64e-2)" "unprognostic (1.51e-5)" "unprognostic (3.23e-4)" "unprognostic (5.52e-2)" "unprognostic (1.44e-1)" "unprognostic (6.46e-2)" "unprognostic (1.13e-1)" "unprognostic (1.81e-1)" "unprognostic (6.40e-6)" "unprognostic (1.14e-1)" "unprognostic (7.20e-2)" "unprognostic (3.86e-3)" "unprognostic (2.34e-1)" "unprognostic (1.30e-2)" "unprognostic (3.66e-2)" 1.3 1.6 0.6 0.7 0.9 0.0 1.6 2.9 1.6 1.8 0.0 1.3 0.3 1.8 1.5 1.1 1.6 1.3 1.1 0.8 1.3 1.1 1.0 1.0 0.5 1.1 0.6 2.1 0.5 1.2 1.2 0.3 1.0 1.4 1.1 1.8 1.3 1.5 0.4 0.4 0.7 1.7 0.8 1.0 0.7 1.0 0.6 0.4 1.4 0.4 0.6 1.3 1.0 1.3 0.0 1.5 7.5 0.0 4.4 3.9 0.0 2.3 3.2 5.0 4.9 0.3 0.8 0.0 0.4 1.8 6.2 0.3 0.1 0.5 4.3 0.0 0.3 0.0 1.4 0.0 3.6 0.0 0.0 2.2 0.0 3.1 2.2 3.2 5.4 0.0 0.0 0.0 4.9 0.1 0.0 0.0 4.7 0.0 2.2 0.0 5.7 0.0 2.4 1.0 0.2 3.9 0.0 0.1 0.0 2.7 0.4 0.0 6.4 2.5 1.9 0.8 2.2 0.1 0.0 0.0 1.5 0.0 0.9 0.0 2.3 0.0 0.7 3.5 0.1 1.8 0.2 0.2 3.2 0.5 0.6 0.4 0.0 0.9 3.5 0.3 0.1 0.6 0.6 0.9 2.9 1.6 0.8 1.3 1.1 0.6 1.0 0.8 0.6 1.3 7.8 0.0 2.7 19.2 2.8 2.5 23.1 2.8 5.7 9.4 4.8 5.2 1.9 1.5 3.5 5.5 12.5 0.0 2.7 1.7 0.0 7.0 8.7 2.9 7.1 6.7 7.1 0.4 51.1 1.8 0.0 7.7 2.0 6.6 1.3 4.1 1.8 0.7 1.0 6.7 56.7 1.5 0.0 1.9 3.6 2.1 4.1 4.1 0.0 20.6 3.8 4.1 1.0 45.8 26.5 2.9 1.9 3.4 1.2 12.4 0.5 2.9 1.3 5.3 0.0 8.8 7.5 2.4 0.3 3.0 1.7 0.1 1.5 4.7 1.3 19.6 HEATR4 MGC48595 ENSG00000187105 "HEAT repeat containing 4" Q86WZ0 14 73478484-73558947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4;testis: 11.5" "Cell type enhanced" "Detected in some" "Astrocytes: 27.4;Early spermatids: 85.5;Excitatory neurons: 19.8;Inhibitory neurons: 16.9;Late spermatids: 29.3;Oligodendrocyte precursor cells: 13.0" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "cerebellum: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.2;SCLC-21H: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003642, HPA079348" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles Cytosol "HPA003642: AB_1079376, HPA079348: " "unprognostic (5.25e-2)" "unprognostic (2.45e-3)" "unprognostic (2.85e-2)" "unprognostic (1.36e-2)" "unprognostic (2.53e-2)" "unprognostic (2.60e-2)" "unprognostic (3.50e-1)" "unprognostic (8.09e-2)" "unprognostic (3.13e-1)" "unprognostic (1.51e-1)" "unprognostic (4.49e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (5.50e-2)" "unprognostic (1.96e-1)" "unprognostic (4.82e-3)" 0.5 0.5 0.2 0.8 0.2 0.9 0.4 6.4 1.0 0.7 0.0 0.4 1.9 1.0 0.3 0.6 0.6 0.8 0.6 0.8 0.0 0.4 0.8 0.5 1.6 0.0 0.0 1.0 0.9 0.2 0.5 0.3 0.1 0.4 0.1 2.9 0.8 0.1 1.9 3.6 0.8 0.1 0.0 1.0 0.7 11.5 0.1 0.0 1.0 0.0 0.0 0.3 0.5 0.8 0.7 0.8 0.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.2 0.2 0.8 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.5 0.0 0.8 0.2 0.2 0.0 2.2 0.2 0.9 0.3 0.2 0.7 0.4 0.4 0.3 0.0 1.1 2.4 0.3 0.8 1.1 1.2 0.5 1.3 0.1 0.4 0.1 0.9 0.7 0.1 0.6 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 0.4 0.1 0.2 0.5 0.5 0.3 0.0 0.6 0.5 0.5 0.3 0.3 0.0 0.2 0.2 0.1 0.2 0.2 6.4 1.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.2 0.0 1.5 27.4 0.2 0.3 0.5 0.1 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 85.5 0.3 0.3 0.4 0.0 0.0 19.8 0.0 0.2 0.5 0.0 0.9 0.0 0.4 0.0 0.6 0.1 0.0 16.9 0.2 0.0 0.0 1.0 29.3 0.6 0.3 0.0 3.7 0.0 0.6 0.0 13.0 6.8 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.0 0.9 0.7 11.1 1.6 0.0 0.9 0.1 0.4 0.1 0.0 0.1 HEPACAM "FLJ25530, GLIALCAM" ENSG00000165478 "Hepatic and glial cell adhesion molecule" Q14CZ8 11 124919205-124936412 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Cell cycle, Growth arrest, Growth regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 222.6;choroid plexus: 79.7" "Group enriched" "Detected in some" 9 "Astrocytes: 184.8;Oligodendrocyte precursor cells: 72.9;Oligodendrocytes: 163.2" "Cancer enriched" "Detected in some" 12 "glioma: 29.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "Hep G2: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017613, CAB025486" Enhanced Approved Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB025486: , HPA017613: AB_1850595" "unprognostic (3.22e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-1)" "unprognostic (6.41e-2)" "unprognostic (1.47e-1)" "unprognostic (9.16e-2)" "unprognostic (2.25e-1)" "unprognostic (7.58e-2)" "unprognostic (1.33e-2)" "unprognostic (1.06e-6)" "unprognostic (2.62e-1)" "unprognostic (3.21e-1)" 15.6 0.3 172.8 0.2 203.3 0.0 2.5 170.4 162.1 0.2 79.7 0.4 0.1 0.1 0.1 0.1 0.0 0.1 0.2 163.2 156.1 0.1 16.2 0.0 0.2 222.6 182.8 0.0 0.0 0.0 0.8 0.0 183.6 0.2 0.2 1.8 0.2 0.5 0.1 0.0 0.2 0.1 205.7 0.0 0.1 0.2 182.0 0.0 0.0 0.3 0.6 0.0 0.1 212.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.2 172.8 203.3 170.4 162.1 163.2 156.1 222.6 182.8 183.6 205.7 182.0 212.2 0.1 0.0 0.0 184.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 11.2 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.6 0.0 15.5 0.0 72.9 163.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.2;Endothelial cells: 47.6;Extravillous trophoblasts: 112.6;Skeletal myocytes: 74.5" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cell line enhanced" "Detected in many" "HEK 293: 125.7;PC-3: 28.8;SK-MEL-30: 93.3;WM-115: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" 21.1 2.2 17.4 2.1 23.0 0.6 19.0 19.4 19.1 7.2 9.6 6.7 1.7 3.5 0.9 2.8 3.9 4.2 23.9 18.4 20.3 2.8 2.8 15.2 2.2 18.1 21.0 2.0 3.4 3.3 18.4 17.8 19.3 6.0 2.6 5.3 10.1 1.7 19.5 4.2 5.8 3.2 19.1 2.4 4.8 3.1 22.8 3.4 6.5 16.2 2.5 9.3 5.2 15.4 1.7 0.1 1.1 9.1 0.8 0.7 22.0 2.1 2.1 0.3 0.3 0.1 0.1 3.3 2.3 1.0 1.0 4.6 4.9 0.1 0.2 0.5 125.7 0.0 4.1 2.1 1.4 0.0 0.7 1.3 3.7 0.1 16.2 0.4 3.4 0.0 9.0 3.6 1.3 0.1 0.0 0.5 0.1 0.3 28.8 0.0 4.6 3.3 0.4 3.9 5.2 14.6 0.1 2.4 93.3 19.6 0.1 0.1 2.0 0.7 2.4 0.0 1.8 3.3 0.7 0.2 3.4 0.0 31.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 1.3 0.0 0.0 0.0 17.4 23.0 19.4 19.1 18.4 20.3 18.1 21.0 19.3 19.1 22.8 15.4 105.2 0.0 1.8 15.0 0.8 3.2 3.4 27.6 2.8 6.8 8.6 12.2 4.3 0.0 19.5 0.0 0.0 6.8 1.8 5.3 15.6 2.6 4.6 12.6 4.1 47.6 36.8 0.0 7.7 1.2 112.6 5.3 1.5 33.5 10.8 1.9 41.0 0.9 1.8 21.9 8.0 2.0 26.4 0.6 5.7 3.2 0.0 2.3 33.8 20.6 0.0 10.9 0.0 18.6 1.0 0.7 7.5 0.4 0.8 1.7 0.2 0.4 7.7 12.2 0.0 74.5 12.1 0.6 15.4 3.4 3.0 23.4 1.1 1.5 2.5 2.6 HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628172-120682269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 200.3;liver: 752.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 103.7;Endometrial ciliated cells: 113.9;Glandular and luminal cells: 127.8;Hepatocytes: 534.7;Proximal tubular cells: 477.5" "Cancer enriched" "Detected in many" 4 "liver cancer: 119.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "CACO-2: 55.8;EFO-21: 82.7;Hep G2: 186.6;OE19: 328.0;RPTEC TERT1: 212.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.2" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" NA NA 700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA047374: AB_2680019, HPA052359: AB_2681798" "unprognostic (1.36e-1)" "unprognostic (9.89e-2)" "unprognostic (3.93e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (5.65e-3)" "unprognostic (7.20e-2)" "unprognostic (6.05e-2)" "unprognostic (2.41e-3)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (4.29e-3)" "unprognostic (8.57e-2)" "unprognostic (1.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" 0.4 0.3 0.4 2.5 1.9 0.5 12.5 0.6 0.8 27.4 1.5 16.7 31.6 3.1 13.0 0.4 4.2 61.7 0.3 0.5 0.4 200.3 752.6 0.8 0.4 0.4 0.4 0.2 31.2 7.0 0.2 0.2 0.4 44.5 20.3 0.7 4.2 4.2 0.1 0.9 25.6 0.5 0.4 0.6 25.5 0.1 0.5 0.7 55.1 0.2 0.1 0.2 0.1 0.6 0.0 12.3 4.6 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 55.8 10.7 0.1 82.7 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.2 186.6 0.0 0.4 1.0 0.0 0.2 0.1 0.0 0.1 0.1 0.4 0.0 0.3 0.5 0.0 0.0 0.2 0.3 328.0 0.0 0.1 0.3 0.1 212.2 0.0 0.2 0.2 0.2 0.9 0.0 0.0 0.2 1.0 0.6 0.1 0.9 0.2 0.1 0.0 0.3 0.5 0.2 0.8 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.4 1.9 0.6 0.8 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.6 0.1 0.0 2.0 0.3 5.9 0.0 0.4 0.6 0.0 0.3 7.5 1.7 0.3 81.5 4.9 27.6 2.1 0.0 0.3 18.5 103.7 7.2 0.2 113.9 17.1 1.2 43.8 24.0 3.2 17.8 0.0 0.4 19.4 127.8 1.3 0.0 16.4 534.7 0.2 0.0 0.6 16.0 2.0 16.1 0.0 0.0 0.0 21.3 0.0 1.9 2.0 4.2 0.0 0.0 0.5 12.1 35.6 0.0 0.0 12.9 54.6 477.5 4.1 0.2 0.0 0.2 1.1 0.1 0.0 0.0 0.0 0.0 3.8 0.4 9.1 0.4 HHAT "FLJ10724, GUP2, MART-2, MART2, rasp, sit, ski, Skn" ENSG00000054392 "Hedgehog acyltransferase" Q5VTY9 1 210328252-210676296 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 25.8;Excitatory neurons: 47.7;Microglial cells: 20.6;Oligodendrocytes: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Group enriched" "Detected in many" 5 "B-cells: 1.8;dendritic cells: 3.7;T-cells: 1.3" "Cell line enhanced" "Detected in many" "HMC-1: 13.6;LHCN-M2: 11.6;RH-30: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016462 Approved Approved "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA016462: AB_2669360" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" "unprognostic (1.86e-1)" "unprognostic (5.02e-3)" "unprognostic (8.89e-3)" "unprognostic (4.81e-2)" "unprognostic (3.32e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (1.67e-3)" "unprognostic (1.43e-1)" "unprognostic (4.13e-3)" "prognostic favorable (8.47e-7)" "unprognostic (2.55e-1)" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (5.67e-2)" 2.1 6.5 1.1 0.6 1.1 0.4 3.3 0.3 1.6 3.4 3.6 2.3 1.1 2.5 3.1 2.8 2.8 2.2 2.4 1.0 0.4 4.0 2.7 2.1 0.8 0.7 0.8 2.1 2.3 1.7 3.2 1.3 0.6 4.0 1.3 1.7 4.4 2.0 0.3 3.4 2.5 1.1 0.9 2.2 1.8 2.5 0.6 2.0 4.6 0.2 0.8 3.1 2.9 0.9 0.8 0.9 2.3 1.3 1.0 1.3 4.8 1.2 1.1 1.9 3.1 0.2 0.9 0.0 1.2 0.9 3.1 0.6 0.5 0.5 2.2 1.7 1.2 0.0 0.1 1.1 0.2 0.3 13.6 1.2 2.7 1.6 1.2 3.2 0.3 1.2 0.0 0.0 11.6 1.2 0.6 0.0 0.6 0.7 0.1 1.3 12.4 0.0 7.5 2.6 1.9 7.8 2.1 0.0 6.0 5.9 4.0 0.7 1.7 2.8 8.5 1.6 4.7 3.8 0.2 0.0 1.1 0.8 2.3 0.0 0.3 0.0 0.7 0.4 1.3 1.5 0.9 0.8 0.4 1.8 0.0 0.2 0.0 0.1 0.1 3.7 0.2 0.4 1.1 1.1 0.3 1.6 1.0 0.4 0.7 0.8 0.6 0.9 0.6 0.9 2.0 0.0 2.4 25.8 5.3 2.2 5.7 2.8 6.8 0.5 5.8 2.4 2.4 4.3 1.2 9.2 0.0 4.6 13.9 1.9 3.9 2.6 1.2 8.8 2.6 2.0 0.0 0.4 47.7 0.7 3.6 3.0 2.6 5.8 0.0 4.6 3.6 2.5 1.9 0.0 11.8 2.7 4.1 2.9 0.5 0.5 1.2 1.5 0.0 20.6 1.0 15.6 0.0 17.1 26.0 1.2 2.1 0.4 2.2 3.7 2.3 0.6 12.9 0.5 0.0 1.7 1.7 0.3 1.3 3.1 2.6 2.2 2.8 0.4 2.0 5.2 HIVEP1 "CIRIP, CRYBP1, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A" ENSG00000095951 "HIVEP zinc finger 1" P15822 6 12008762-12164999 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050724, HPA067457" Approved Supported "Nucleoplasm,Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies, Mitochondria, Cytosol" "HPA050724: AB_2616457, HPA067457: " "unprognostic (2.55e-1)" "unprognostic (5.85e-2)" "unprognostic (1.15e-1)" "unprognostic (6.03e-2)" "unprognostic (1.75e-2)" "unprognostic (5.65e-3)" "unprognostic (4.83e-2)" "unprognostic (1.38e-1)" "unprognostic (2.20e-1)" "unprognostic (1.85e-1)" "unprognostic (5.69e-2)" "unprognostic (1.98e-1)" "unprognostic (4.40e-2)" "unprognostic (3.01e-2)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (2.38e-1)" 7.2 2.3 0.8 8.0 3.0 16.7 5.5 0.7 3.0 7.4 6.5 6.4 5.0 5.9 4.5 7.4 6.1 7.3 3.8 2.2 0.8 4.5 11.7 6.3 8.0 1.3 2.8 6.5 6.7 10.5 3.3 4.9 0.5 6.9 6.6 5.8 4.8 5.8 2.8 5.7 5.2 6.2 0.0 6.0 4.9 4.8 1.2 9.1 4.9 6.2 8.3 9.3 3.3 1.6 8.1 5.9 7.5 4.2 5.8 7.3 7.2 6.4 5.5 5.2 5.7 3.8 4.2 6.7 13.6 7.8 12.4 7.6 7.4 9.2 7.1 14.6 4.3 3.1 5.6 3.7 4.7 3.7 2.5 5.1 9.0 10.6 16.3 11.0 15.5 4.6 32.9 7.5 11.5 6.0 5.9 3.3 6.4 2.8 2.7 3.2 9.8 10.7 3.1 8.7 7.1 5.2 15.9 12.8 4.3 16.6 7.6 4.7 25.2 13.0 5.8 12.3 7.4 30.0 27.3 12.0 4.0 4.8 5.5 2.4 1.8 2.1 1.2 2.0 0.9 3.1 2.0 0.8 1.2 4.8 3.4 2.1 11.7 3.3 5.2 9.0 4.4 0.7 0.8 3.0 0.7 3.0 2.2 0.8 1.3 2.8 0.5 0.0 1.2 1.6 40.2 28.9 16.9 74.7 35.6 32.2 25.4 7.4 30.7 20.4 12.3 10.9 10.4 17.2 17.6 7.3 12.5 3.4 18.7 17.5 3.9 5.6 2.5 37.7 16.4 20.3 10.8 6.5 94.6 7.2 1.8 25.2 22.4 51.0 7.6 7.0 6.4 12.3 5.9 21.9 68.3 14.4 4.1 9.6 47.9 1.8 3.7 23.1 19.6 44.0 29.6 13.1 5.2 59.3 25.0 11.5 10.3 4.5 33.6 25.2 6.7 2.5 16.7 9.7 0.0 21.0 17.1 3.9 3.5 18.7 33.4 5.2 18.8 6.6 8.6 23.7 HIVEP3 "FLJ16752, KBP-1, KBP1, KIAA1555, KRC, Schnurri-3, SHN3, ZAS3, ZNF40C" ENSG00000127124 "HIVEP zinc finger 3" Q5T1R4 1 41506365-42035925 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.6" "Group enriched" "Detected in many" 5 "Astrocytes: 83.9;Excitatory neurons: 219.6;Inhibitory neurons: 271.9;Microglial cells: 163.9;Oligodendrocyte precursor cells: 83.9;Oligodendrocytes: 196.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 18.8;hTEC/SVTERT24-B: 9.5;Karpas-707: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005728 Approved Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA005728: AB_10612117" "unprognostic (2.87e-3)" "unprognostic (2.38e-2)" "unprognostic (4.65e-2)" "unprognostic (2.56e-1)" "unprognostic (1.55e-2)" "unprognostic (6.50e-2)" "unprognostic (2.70e-3)" "unprognostic (3.73e-1)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "unprognostic (2.07e-8)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" 1.6 0.6 0.8 2.1 2.1 1.6 1.4 1.4 1.6 0.4 0.0 0.5 0.4 0.4 0.3 1.9 0.5 0.7 0.8 2.0 0.0 1.0 0.3 1.9 1.7 0.7 0.4 0.5 0.8 0.4 2.1 0.6 1.0 1.4 0.5 0.6 1.6 0.3 0.6 4.6 0.6 0.8 0.1 1.1 0.7 0.3 0.5 6.6 1.5 0.4 2.1 1.8 0.5 0.3 1.9 0.6 0.2 1.8 2.2 1.0 0.0 0.9 0.2 2.3 4.0 0.1 0.3 4.0 0.6 1.0 1.5 2.7 0.4 0.4 3.1 18.8 0.5 0.2 0.9 0.0 0.4 0.3 0.3 5.6 0.4 9.5 1.1 0.6 0.5 1.3 0.0 11.0 1.8 1.2 3.0 0.8 0.6 0.6 2.3 2.0 2.9 2.2 1.5 0.4 2.0 0.6 2.6 0.7 0.5 1.1 0.9 3.4 3.4 2.0 2.2 0.6 4.6 3.3 1.4 2.6 8.1 0.2 7.5 0.0 0.5 0.0 0.6 1.1 0.1 0.1 0.2 0.3 0.4 0.4 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.4 0.8 2.1 1.4 1.6 2.0 0.0 0.7 0.4 1.0 0.1 0.5 0.3 5.9 6.4 10.5 83.9 9.6 23.7 26.5 4.3 17.6 16.4 15.1 11.0 6.9 5.7 8.2 1.8 2.1 0.4 17.6 3.5 1.9 3.1 9.9 1.2 7.7 7.5 3.6 4.4 219.6 2.7 4.4 11.1 1.5 2.8 1.3 0.2 11.4 2.5 6.2 25.2 271.9 1.2 2.0 6.5 17.3 31.9 8.7 15.0 5.4 163.9 9.1 16.0 27.8 83.9 196.0 3.1 0.1 4.1 3.3 15.5 1.9 3.2 1.1 3.5 6.6 23.9 7.4 11.3 8.6 23.7 8.7 0.8 14.5 10.0 0.9 11.1 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Mental retardation, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 374.0;Horizontal cells: 304.5;Late spermatids: 1034.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Supported Mitochondria NA NA 560000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" 47.0 24.4 61.0 45.0 65.7 60.3 40.6 58.0 76.6 54.7 64.2 60.1 13.1 41.3 11.2 129.9 37.0 25.7 150.8 69.1 62.7 49.2 8.5 48.1 34.1 56.7 59.8 19.9 12.3 25.0 44.9 49.3 71.1 52.9 31.9 147.6 67.1 53.1 193.5 102.6 29.2 49.8 40.0 40.3 61.6 77.2 53.5 44.9 71.0 146.7 47.6 74.3 80.9 54.1 101.6 56.6 74.2 71.1 81.0 60.4 47.1 98.3 256.5 128.5 138.0 16.3 11.0 7.3 75.8 165.9 92.9 86.2 69.9 220.0 122.0 67.5 54.5 250.0 58.3 1.1 91.7 5.1 181.2 91.5 125.8 184.5 407.6 160.8 135.4 36.8 424.5 51.3 178.7 167.7 29.7 13.1 113.8 51.7 247.0 44.8 45.0 0.6 88.7 117.4 75.7 88.7 112.6 215.4 65.2 104.3 117.7 16.5 140.4 190.5 86.4 106.5 139.6 61.1 42.8 17.4 247.3 130.4 56.1 68.7 88.8 44.6 41.5 125.2 69.0 33.5 47.9 47.6 81.0 19.9 41.7 33.9 20.9 31.2 135.4 9.1 58.1 110.4 61.0 65.7 58.0 76.6 69.1 62.7 56.7 59.8 71.1 40.0 53.5 54.1 26.1 25.6 32.4 38.2 26.5 48.3 50.5 37.8 43.9 83.9 33.1 21.7 130.6 4.3 34.2 27.6 54.2 70.6 14.6 30.3 13.7 28.6 374.0 32.6 28.0 37.9 18.7 104.8 53.8 30.6 93.3 30.3 41.3 34.5 23.4 72.6 26.7 1.1 49.4 304.5 49.8 28.7 44.7 41.7 21.9 1034.1 15.2 51.3 37.4 29.0 35.3 32.9 20.6 14.1 3.5 54.6 11.1 18.4 19.1 29.1 0.7 1.1 30.7 95.5 19.7 22.2 43.1 5.3 6.2 86.0 51.7 118.9 30.5 28.3 19.3 43.5 HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 129.3;lymphoid tissue: 76.6" "Group enriched" "Detected in some" 13 "Early spermatids: 11.1;Hofbauer cells: 34.5;Kupffer cells: 43.9;Macrophages: 38.8;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4" "Immune cell enhanced" "Detected in many" "basophil: 569.7" "Group enriched" "Detected in many" 13 "granulocytes: 569.7;monocytes: 200.9" "Cell line enriched" "Detected in some" 5 "U-937: 20.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2000000 "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA056743: AB_2683222" "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavorable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" 8.4 4.5 0.0 19.0 0.2 129.3 2.6 1.4 1.6 0.8 0.2 2.5 2.0 1.0 0.1 0.9 5.1 2.1 4.0 0.2 0.0 1.8 5.2 25.1 4.2 0.0 0.0 1.0 1.5 0.1 0.7 2.8 0.0 1.1 1.4 0.1 1.5 0.3 0.9 0.5 3.1 7.9 0.0 76.6 2.1 1.3 2.4 1.4 1.3 0.5 0.7 4.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.5 0.1 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.6 0.0 569.7 92.5 204.8 0.3 179.4 0.2 0.4 0.2 0.1 30.2 0.2 0.1 0.1 32.2 0.2 200.9 1.4 0.2 43.6 0.0 0.2 1.4 1.6 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 11.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.4 1.3 0.0 0.4 0.2 34.5 0.0 0.4 0.0 0.0 43.9 0.9 1.8 0.0 38.8 0.0 1.0 14.6 0.0 2.1 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.0 HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29945884 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 3747.8;Proximal enterocytes: 5267.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 1363.9;fHDF/TERT166: 360.3;HBEC3-KT: 366.7;RPMI-8226: 372.1;U-266/70: 344.6" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" 635.4 714.2 15.0 34.8 15.5 137.7 566.7 14.7 36.5 504.9 18.0 737.5 278.3 476.1 181.1 366.8 390.3 239.9 473.4 14.6 17.0 687.0 392.0 1007.3 132.0 19.1 15.8 338.8 200.0 18.5 406.5 52.1 16.5 370.9 94.6 9.9 364.1 1.2 246.5 673.3 959.1 14.5 16.8 1413.1 442.2 132.6 18.0 138.9 531.9 14.5 178.3 412.3 466.8 18.3 1363.9 35.0 0.0 0.0 205.9 193.7 1.4 1.4 2.5 2.1 2.3 0.2 0.1 4.0 0.6 360.3 179.1 31.2 0.2 366.7 0.5 3.1 13.5 237.5 9.5 7.4 11.2 0.5 14.4 2.0 0.0 2.5 1.1 0.6 0.2 177.8 0.4 1.4 0.5 0.0 1.1 24.3 2.9 0.2 4.1 27.5 2.5 372.1 246.7 276.5 0.6 12.4 29.3 0.2 11.8 82.8 1.6 30.4 5.8 18.7 0.8 5.8 4.0 344.6 92.6 77.7 0.4 199.9 0.2 321.6 119.0 182.7 164.7 95.5 134.8 96.9 125.4 146.3 18.6 64.3 86.5 119.2 248.7 133.1 109.6 54.6 222.2 191.9 15.0 15.5 14.7 36.5 14.6 17.0 19.1 15.8 16.5 16.8 18.0 18.3 1622.4 371.8 478.6 22.9 1316.2 856.4 886.2 1417.5 228.8 30.8 289.6 188.5 147.4 936.5 952.5 503.9 6.2 18.3 1879.4 2631.8 88.0 3747.8 52.2 239.4 374.0 1717.8 955.2 499.4 3.6 1310.0 18.5 743.5 853.7 556.2 603.0 253.3 1266.2 276.4 1840.9 37.0 19.3 1755.3 1265.4 1575.0 1124.0 95.6 704.6 1419.1 635.0 67.5 3258.0 170.4 3201.9 49.3 16.1 1802.9 2452.4 484.1 1110.7 1026.6 5267.3 294.9 609.6 24.4 558.8 397.3 579.2 197.4 23.8 216.5 947.7 31.7 2234.9 1021.3 1225.4 1262.8 HLA-B AS ENSG00000234745 "Major histocompatibility complex, class I, B" P01889 6 31353872-31357188 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 2493.7" "Cell type enhanced" "Detected in all" "monocytes: 5683.6;NK-cells: 7881.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 638.3;EFO-21: 547.1;U-266/70: 1285.6;U-698: 377.2" CAB015418 Enhanced NA NA 190000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB015418: AB_831547" "unprognostic (2.87e-2)" "unprognostic (1.49e-1)" "unprognostic (4.90e-2)" "unprognostic (2.65e-2)" "unprognostic (1.86e-1)" "unprognostic (1.81e-1)" "unprognostic (5.16e-3)" "unprognostic (8.51e-2)" "prognostic favorable (2.90e-4)" "unprognostic (2.69e-3)" "unprognostic (3.05e-2)" "unprognostic (1.59e-1)" "unprognostic (9.28e-3)" "unprognostic (3.27e-1)" "unprognostic (7.83e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-2)" 944.9 581.6 5.5 429.4 8.1 53.5 850.0 5.5 14.4 552.0 6.0 912.0 4.7 567.1 222.1 434.4 488.6 461.2 563.1 4.6 6.7 731.7 488.9 1646.3 1061.9 9.6 10.4 296.9 268.7 24.2 288.3 106.6 7.5 439.2 238.5 8.1 485.9 3.8 237.9 936.4 1295.6 75.4 7.7 2493.7 540.1 132.6 6.7 4.4 593.2 3.8 414.9 476.2 582.0 7.9 638.3 0.0 0.0 0.1 13.5 98.9 3.8 0.5 1.2 0.5 1.1 0.0 1.9 22.7 547.1 111.0 203.2 231.9 116.4 112.4 0.0 2.3 29.9 8.3 0.8 0.0 79.8 0.2 2.4 200.2 0.5 0.0 13.9 183.3 0.4 39.8 1.3 30.2 0.0 0.3 1.5 161.4 0.6 0.0 0.1 19.7 3.4 4.7 163.5 0.6 0.9 3.7 5.5 1.4 1.4 0.2 32.6 6.2 134.7 21.4 4.8 4.9 2.3 1285.6 291.0 377.2 1.1 6.5 0.6 141.1 196.5 232.6 233.0 163.6 215.7 162.4 194.8 198.8 150.8 113.0 150.9 212.0 420.5 179.3 123.6 127.3 213.1 400.2 5.5 8.1 5.5 14.4 4.6 6.7 9.6 10.4 7.5 7.7 6.7 7.9 2836.3 913.5 1007.9 14.0 2936.9 1165.9 761.2 1139.6 396.1 27.7 533.2 550.2 168.5 1382.6 948.3 388.1 6.2 31.4 3876.2 3264.3 68.4 4206.8 63.9 311.6 349.2 2480.7 836.0 550.3 1.4 1771.3 182.3 777.7 1044.4 773.2 620.5 212.5 2189.2 701.5 2602.0 60.6 3.4 2121.8 1129.1 4229.7 2158.6 65.7 644.9 2674.7 891.2 126.5 5683.6 209.2 7881.6 25.1 3.9 2085.3 2327.5 306.9 2983.6 993.4 4541.4 183.9 829.4 27.3 1314.8 356.3 729.7 652.9 91.6 360.3 1004.3 50.9 3661.2 1219.5 1527.4 1161.2 HLA-DQA1 "CELIAC1, HLA-DQA" ENSG00000196735 "Major histocompatibility complex, class II, DQ alpha 1" P01909 6 32628179-32647062 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 333.9;lymphoid tissue: 335.8" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 4114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 666.6" "Group enriched" "Detected in all" 19 "B-cells: 287.6;dendritic cells: 666.6;monocytes: 257.6" "Cell line enriched" "Detected in some" 7 "HDLM-2: 1419.1" HPA012315 Enhanced NA NA 200000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA012315: AB_1853930" "unprognostic (4.24e-3)" "unprognostic (1.47e-2)" "unprognostic (1.43e-2)" "unprognostic (7.94e-3)" "unprognostic (1.72e-1)" "unprognostic (6.07e-2)" "unprognostic (3.26e-1)" "unprognostic (5.81e-3)" "unprognostic (2.84e-2)" "unprognostic (1.17e-1)" "unprognostic (4.65e-2)" "unprognostic (1.15e-1)" "unprognostic (5.36e-2)" "unprognostic (6.74e-2)" "unprognostic (2.27e-1)" "unprognostic (7.43e-2)" "unprognostic (1.57e-1)" 61.7 45.7 2.3 111.0 2.2 7.1 41.6 2.4 2.8 49.9 5.2 76.8 0.1 27.7 32.2 32.1 29.1 127.4 20.8 1.6 5.1 39.6 95.1 333.9 335.8 4.3 2.6 18.6 15.0 2.6 15.2 13.7 2.7 15.1 115.8 1.9 34.8 7.8 7.5 30.0 74.0 19.2 5.4 180.0 103.3 12.2 3.4 234.3 26.0 0.0 322.3 175.9 16.3 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 213.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1419.1 0.9 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 4.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 2.4 0.4 0.0 0.1 0.6 0.6 63.2 1.5 156.1 24.4 0.0 0.0 1.9 105.8 0.5 2.4 257.6 1.0 287.6 3.3 16.5 666.6 274.1 0.4 4.3 3.0 8.2 68.3 162.7 21.6 129.0 2.3 2.2 2.4 2.8 1.6 5.1 4.3 2.6 2.7 5.4 3.4 11.1 67.9 12.8 86.3 0.0 972.8 50.2 0.4 4.3 4.6 0.1 9.8 28.6 2.1 7.2 19.4 0.0 2.1 0.8 179.8 0.9 1.9 4.6 0.6 0.5 0.4 97.4 0.0 38.3 0.1 4.6 2.4 14.7 10.7 0.9 50.4 0.8 12.8 0.6 381.0 0.0 0.1 0.4 2.0 518.6 4114.3 1.3 3.1 874.3 71.2 12.2 957.1 1.0 4.1 0.0 0.2 2.1 0.1 0.0 96.1 1.5 1.8 6.5 27.3 2.5 6.6 1.2 5.3 0.0 0.7 2.5 41.6 2.1 56.0 1.2 2.7 7.6 HLA-DQA2 HLA-DXA ENSG00000237541 "Major histocompatibility complex, class II, DQ alpha 2" P01906 6 32741391-32747198 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.8;lymphoid tissue: 27.1" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 1196.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (4.06e-3)" "unprognostic (2.46e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-2)" "unprognostic (2.69e-1)" "unprognostic (5.44e-2)" "unprognostic (2.64e-1)" "unprognostic (2.57e-2)" "unprognostic (8.85e-2)" "unprognostic (4.40e-1)" "unprognostic (1.04e-1)" "unprognostic (7.67e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-2)" "unprognostic (3.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.48e-2)" 10.9 4.5 0.0 0.0 0.0 0.0 7.2 0.0 0.0 3.1 0.0 3.9 0.0 2.1 0.0 3.0 2.8 0.1 2.3 0.0 0.0 5.8 1.7 20.8 0.0 0.0 0.0 0.9 1.2 0.0 2.5 0.0 0.0 2.5 0.0 0.0 3.4 0.0 1.4 8.4 11.6 0.0 0.0 27.1 2.9 0.6 0.0 0.3 3.7 0.0 0.3 3.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.1 3.2 3.6 0.0 179.2 23.5 0.3 1.8 1.2 0.0 2.5 1.3 0.5 0.0 7.5 3.7 0.0 0.2 144.1 0.1 0.0 0.2 0.7 0.1 0.2 20.6 2.4 0.4 0.0 0.0 0.8 1.6 0.0 0.3 0.0 0.8 2.2 0.3 110.0 0.0 0.0 0.0 0.0 78.9 1196.5 2.0 1.2 243.1 24.9 0.0 125.3 0.0 8.2 0.0 0.0 0.2 0.0 0.0 9.5 0.0 0.0 11.2 12.4 0.0 6.6 0.7 1.2 0.1 0.3 0.1 23.3 0.4 13.8 0.0 0.0 0.7 HLCS HCS ENSG00000159267 "Holocarboxylase synthetase" P50747 21 36748626-36990236 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 99.7;Oligodendrocyte precursor cells: 79.9;Oligodendrocytes: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017379 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA017379: AB_1850768" "prognostic unfavorable (7.72e-4)" "unprognostic (2.41e-1)" "unprognostic (3.93e-2)" "unprognostic (2.05e-1)" "unprognostic (2.75e-1)" "unprognostic (1.44e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-1)" "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-1)" "unprognostic (7.44e-2)" "unprognostic (2.43e-1)" "unprognostic (2.55e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-3)" "unprognostic (3.02e-1)" 5.0 5.1 4.9 4.2 5.5 3.3 7.4 9.1 5.8 5.1 9.4 4.7 4.2 4.0 7.0 6.1 5.3 4.2 3.7 6.3 5.4 6.4 10.6 4.9 3.7 5.9 4.6 3.8 7.6 10.6 8.8 4.1 6.3 8.9 4.4 6.1 8.5 6.6 13.3 2.8 4.9 4.5 4.1 3.1 5.7 5.7 5.4 3.3 10.7 6.2 4.3 5.4 2.8 5.5 23.8 10.4 13.0 9.6 14.8 13.7 13.3 13.0 12.7 7.1 7.0 10.8 11.0 10.6 6.4 21.4 13.0 8.2 5.9 11.6 5.5 21.0 9.2 16.4 9.6 6.7 14.9 8.6 11.0 10.2 17.0 10.6 23.6 15.5 9.0 12.0 19.7 31.9 17.4 14.2 4.6 5.4 21.8 16.7 11.3 7.1 7.5 11.2 10.8 24.8 8.3 9.9 16.7 8.8 14.8 10.0 16.2 9.1 10.5 9.1 2.7 8.9 7.8 25.6 19.8 7.1 14.6 11.1 10.7 1.9 0.8 0.8 3.6 2.0 2.9 1.2 1.9 2.3 0.8 1.3 2.4 2.2 1.2 4.8 5.1 1.9 1.6 1.8 4.9 5.5 9.1 5.8 6.3 5.4 5.9 4.6 6.3 4.1 5.4 5.5 3.0 9.6 12.5 46.4 4.1 3.3 9.2 5.3 6.8 12.8 9.4 7.4 4.5 8.6 8.4 12.9 22.9 8.9 5.1 3.5 7.9 7.8 5.6 8.0 8.0 3.8 6.0 7.4 86.2 8.1 5.4 5.1 9.7 8.0 5.7 7.9 4.2 18.5 4.6 18.5 99.7 5.2 4.1 5.1 2.1 4.3 4.4 4.0 0.0 45.9 3.2 5.6 8.2 79.9 80.1 9.0 2.9 7.2 4.2 7.8 8.0 6.1 9.2 14.2 0.0 9.0 6.8 5.2 11.5 8.7 4.0 5.1 5.5 11.1 5.4 6.9 HLF MGC33822 ENSG00000108924 "HLF transcription factor, PAR bZIP family member" Q16534 17 55264960-55325187 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 122.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.7;Excitatory neurons: 77.5;Hepatocytes: 156.8;Horizontal cells: 92.5;Microglial cells: 74.0" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Region enhanced" "Detected in many" "cerebral cortex: 53.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 163.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068156, HPA071210" Enhanced Nucleoplasm Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA068156: AB_2685963, HPA071210: AB_2686361" "unprognostic (1.24e-1)" "unprognostic (1.19e-3)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "prognostic favorable (1.88e-4)" "unprognostic (5.30e-3)" "prognostic favorable (2.71e-7)" "unprognostic (1.42e-1)" "unprognostic (3.44e-2)" "unprognostic (1.24e-3)" "unprognostic (2.19e-1)" "prognostic favorable (3.55e-6)" "unprognostic (8.47e-2)" "unprognostic (1.64e-1)" "unprognostic (6.85e-2)" "unprognostic (1.60e-2)" 15.1 21.5 9.8 1.9 23.1 0.4 15.4 0.0 53.3 14.4 0.0 18.0 1.4 14.4 11.0 26.3 12.2 7.8 24.1 17.6 0.0 12.7 122.4 13.4 2.2 0.0 0.6 50.0 2.9 4.0 9.9 1.0 0.0 13.2 3.4 43.2 24.1 12.4 7.7 16.7 4.3 12.3 0.0 8.2 6.1 4.1 3.9 3.4 34.3 9.9 7.7 12.3 7.8 17.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.9 0.5 0.0 0.0 0.0 0.4 0.2 0.0 27.3 0.7 0.0 0.1 163.0 0.1 0.9 0.2 0.1 0.7 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.6 1.1 0.0 0.1 0.0 2.4 0.0 0.4 0.4 13.0 0.1 11.1 0.6 0.0 7.2 0.2 0.0 0.2 0.0 0.1 0.8 0.2 0.6 0.5 5.1 4.9 0.0 0.3 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 9.8 23.1 0.0 53.3 17.6 0.0 0.0 0.6 0.0 0.0 3.9 17.2 13.8 3.2 42.8 22.2 0.4 22.3 4.4 1.4 56.9 120.7 5.9 16.4 38.6 12.8 6.3 7.3 10.4 0.1 0.5 0.0 11.7 1.9 1.3 0.1 6.2 19.7 3.0 0.8 77.5 0.9 0.0 17.6 0.0 0.6 0.0 0.5 6.1 156.8 0.1 92.5 36.6 0.6 0.0 3.5 4.0 4.7 28.3 0.7 10.6 74.0 0.1 60.7 0.0 24.6 6.9 0.4 0.0 39.1 1.5 1.3 2.8 23.3 1.0 15.0 13.1 4.5 7.4 0.4 5.0 33.7 27.6 1.2 3.8 0.5 0.4 0.4 HLX "HB24, HLX1" ENSG00000136630 "H2.0 like homeobox" Q14774 1 220879431-220885059 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 86.5" "Cell type enhanced" "Detected in many" "Adipocytes: 35.7;Endothelial cells: 32.5;Hepatic stellate cells: 47.5;Hofbauer cells: 34.1;Kupffer cells: 24.8;Langerhans cells: 23.5;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 65.1;neutrophil: 55.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 65.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 32.4;THP-1: 100.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA005968 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "HPA005968: AB_1079066" "unprognostic (6.18e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.57e-2)" "unprognostic (9.19e-3)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (5.14e-3)" "unprognostic (1.06e-1)" "unprognostic (9.73e-2)" "unprognostic (3.19e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.28e-6)" "unprognostic (8.44e-3)" "unprognostic (3.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" 35.2 4.7 1.4 10.3 1.3 86.5 18.6 1.4 2.0 7.5 1.5 44.4 4.8 5.5 0.5 3.9 9.3 9.6 18.9 2.0 1.6 6.8 21.8 23.1 8.5 1.9 1.7 4.2 4.3 1.3 3.0 13.8 2.0 6.3 2.0 0.0 3.5 0.4 9.2 8.7 18.9 5.6 1.9 15.7 5.2 1.8 2.6 2.1 9.5 4.2 2.3 11.0 8.8 1.9 0.0 2.1 0.0 3.2 9.2 14.7 3.0 11.4 18.9 12.8 10.6 0.2 0.3 0.0 0.1 6.8 2.5 0.0 0.5 0.0 5.3 3.0 5.9 0.0 1.1 0.3 15.1 3.9 0.8 15.4 0.2 14.7 0.8 1.1 5.7 0.0 4.0 0.0 1.6 0.0 0.0 10.3 0.3 0.0 5.2 0.3 9.0 0.1 0.8 0.1 0.0 2.4 0.7 0.0 32.4 0.1 0.0 100.4 1.8 8.7 0.0 1.3 9.3 0.0 0.0 0.0 14.1 12.3 3.6 65.1 10.4 22.3 0.0 3.4 0.0 5.7 0.0 0.0 13.0 2.7 0.0 0.0 55.9 0.7 0.7 8.7 0.4 3.3 1.4 1.3 1.4 2.0 2.0 1.6 1.9 1.7 2.0 1.9 2.6 1.9 35.7 9.6 5.3 1.0 4.3 2.8 0.1 0.0 0.6 0.1 0.5 1.3 5.7 0.0 0.0 0.0 0.0 0.6 3.0 0.4 0.0 0.5 0.5 0.2 2.6 32.5 0.0 8.4 0.3 0.4 0.7 8.4 0.5 0.3 3.8 0.1 47.5 10.8 34.1 0.0 0.2 0.3 0.0 24.8 23.5 0.4 2.5 17.8 0.0 4.7 44.2 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.2 0.0 0.1 0.0 0.0 6.6 7.5 10.6 0.1 2.2 0.3 3.1 0.4 1.1 0.4 0.3 0.4 HMCES "C3orf37, DC12, SRAPD1" ENSG00000183624 "5-hydroxymethylcytosine binding, ES cell specific" Q96FZ2 3 129278828-129306186 "Predicted intracellular proteins" "DNA damage" "DNA-binding, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 124.9;Spermatocytes: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044968 Enhanced Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA044968: AB_2679160" "unprognostic (9.18e-3)" "unprognostic (1.11e-3)" "unprognostic (4.16e-2)" "unprognostic (2.80e-2)" "unprognostic (2.93e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.41e-4)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (3.00e-1)" "unprognostic (4.12e-3)" "unprognostic (6.32e-2)" "unprognostic (5.46e-2)" "unprognostic (1.71e-2)" "unprognostic (1.74e-1)" "unprognostic (1.25e-2)" "unprognostic (9.08e-3)" 35.8 22.0 27.6 37.3 32.5 37.8 32.9 26.6 32.4 25.8 22.4 36.1 29.4 24.0 23.0 41.7 27.0 21.1 40.3 29.8 30.1 27.4 53.7 27.1 99.7 27.3 27.6 28.3 15.3 68.9 22.2 20.9 27.6 24.6 30.9 27.7 26.8 26.2 57.7 35.5 28.8 23.2 26.4 29.8 26.4 39.9 32.5 57.1 22.4 48.5 131.0 28.5 28.8 27.1 149.4 66.2 74.4 85.9 90.6 37.8 66.8 51.2 41.5 73.1 56.6 105.0 67.9 286.0 53.9 46.9 57.2 106.3 94.8 110.8 83.7 58.0 51.2 59.7 52.7 76.0 38.8 52.1 41.9 36.7 56.6 61.1 60.2 35.6 45.5 63.5 61.2 244.2 40.9 197.3 74.8 45.1 48.4 108.5 42.8 66.6 63.8 50.5 77.0 88.8 74.0 45.6 114.4 70.8 70.6 45.6 121.0 52.1 36.8 36.3 63.7 87.3 66.5 135.8 87.2 289.3 43.4 41.9 41.1 35.5 25.5 65.0 30.4 27.4 31.6 37.5 36.7 36.3 26.3 62.1 36.1 40.0 52.5 27.2 40.9 28.1 48.0 31.2 27.6 32.5 26.6 32.4 29.8 30.1 27.3 27.6 27.6 26.4 32.5 27.1 26.1 32.1 25.6 11.4 23.5 58.2 71.2 72.4 54.7 21.5 18.8 16.1 35.6 30.0 30.4 22.0 10.4 49.2 32.0 30.8 37.2 39.6 8.6 16.0 10.2 27.8 21.0 28.2 13.6 47.0 37.6 23.3 17.9 15.7 22.2 11.0 20.7 26.1 19.7 26.9 14.7 17.3 32.6 8.1 39.4 8.6 24.5 15.7 58.7 10.3 16.4 38.6 25.7 7.1 10.6 33.8 16.9 31.2 124.9 37.3 19.9 21.1 25.2 12.5 13.1 21.0 27.1 127.8 83.6 30.7 43.9 35.0 47.3 23.9 30.7 61.0 HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.6;lymphoid tissue: 27.3;testis: 27.5" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Erythroid cells: 133.3;Extravillous trophoblasts: 55.1;Late spermatids: 60.9;Spermatocytes: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Centrosome, Cytosol" "CAB002433: AB_564080, HPA040025: AB_2676805, HPA043926: , HPA061524: AB_2684551" "unprognostic (3.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.38e-3)" "unprognostic (8.88e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (5.52e-4)" "prognostic unfavorable (1.93e-7)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.68e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.02e-1)" "unprognostic (0.00e+0)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-2)" 0.8 0.7 0.2 10.1 0.3 20.6 2.1 0.3 0.4 1.1 0.1 6.6 7.4 0.8 0.2 4.0 0.5 0.9 0.8 0.2 0.2 0.7 1.7 0.9 18.1 0.5 0.3 0.2 0.3 0.9 0.2 6.2 0.4 0.5 8.8 0.8 0.8 0.2 1.2 4.2 6.5 2.9 0.3 2.9 3.6 27.5 0.7 27.3 0.7 0.4 17.7 2.2 1.4 0.5 77.0 47.2 94.5 50.8 5.0 9.0 70.3 71.4 34.9 88.0 78.9 96.8 145.1 127.5 66.0 22.2 118.5 86.3 112.4 69.0 148.6 116.1 34.4 76.7 32.3 48.4 1.4 68.7 67.3 2.4 4.1 82.8 64.0 14.7 50.6 85.7 73.2 101.0 93.2 28.5 72.3 38.8 81.9 51.2 51.6 78.0 126.3 63.9 34.8 20.4 78.8 43.8 106.3 32.8 38.6 45.1 97.3 54.5 32.9 63.2 52.4 50.6 97.2 53.7 96.3 102.4 41.4 104.2 61.1 0.2 0.2 0.0 0.1 0.1 0.3 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.5 0.0 0.6 1.5 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.5 0.3 0.4 0.3 0.7 0.5 0.4 0.0 1.1 1.3 6.0 2.5 1.8 4.5 2.8 0.6 3.2 3.7 2.5 4.3 3.2 0.0 0.0 37.3 2.3 5.3 0.0 0.8 86.2 3.8 3.1 3.1 1.2 133.3 0.6 0.2 55.1 4.6 11.7 5.7 0.0 21.6 5.3 3.8 22.2 0.0 0.4 7.8 6.1 8.8 2.7 60.9 2.1 7.6 0.0 0.0 2.3 0.1 1.0 0.5 1.2 0.2 0.3 0.7 22.9 1.5 1.3 2.6 2.8 1.0 6.6 0.6 3.8 100.9 23.3 14.1 1.4 4.5 5.2 1.6 15.6 3.0 HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 612.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2" "Lineage enriched" "Detected in all" 7 "monocytes: 329.2" "Cell line enhanced" "Detected in many" "BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" 150.2 48.9 40.9 64.6 48.8 99.3 20.6 42.4 66.3 28.2 46.4 35.2 106.0 10.4 7.6 48.4 40.7 52.6 18.2 40.6 46.6 96.2 136.5 113.6 57.2 52.3 46.5 139.0 41.7 7.4 9.6 72.2 56.3 6.7 31.1 1.7 15.1 4.0 107.1 74.1 64.5 38.7 45.9 612.2 19.9 17.8 60.7 25.1 11.3 21.4 49.4 46.2 29.2 56.2 12.2 179.1 1.8 37.7 170.9 49.6 869.1 83.2 57.6 42.9 48.6 82.1 11.3 0.1 18.3 83.3 631.2 10.1 11.4 1.9 16.1 308.6 9.2 4.3 51.5 179.3 218.9 11.5 54.8 146.3 4.2 282.3 19.7 74.6 130.9 0.5 0.0 87.4 152.5 6.9 0.2 4.3 18.1 130.4 20.7 1.2 15.6 28.4 35.2 104.5 2.7 2.4 215.8 19.1 15.5 92.5 8.9 3.0 44.3 506.2 22.1 82.5 82.5 53.5 77.0 9.3 489.4 5.7 8.6 11.3 98.8 7.7 1.1 238.8 0.4 24.8 0.7 1.7 44.6 2.9 0.1 0.5 47.1 5.3 329.2 1.1 1.8 70.9 40.9 48.8 42.4 66.3 40.6 46.6 52.3 46.5 56.3 45.9 60.7 56.2 19.3 3.2 19.0 0.0 11.5 16.4 27.5 11.0 10.8 0.0 25.0 9.1 2.9 24.3 10.5 5.5 0.0 50.5 3.5 59.1 21.5 13.6 2.1 39.6 12.9 327.1 16.0 5.7 0.2 1.5 285.2 64.1 9.2 74.6 11.4 98.4 23.6 23.6 494.9 0.0 0.4 8.3 18.3 954.1 175.8 4.1 31.1 271.5 35.6 1.9 184.7 0.4 9.2 0.5 1.4 8.3 26.1 5.3 2.5 110.6 61.5 157.9 7.1 0.6 0.0 40.8 52.7 0.9 4.4 5.5 15.6 502.0 6.8 6.9 6.1 118.3 HNRNPAB "ABBP1, FLJ40338, HNRPAB" ENSG00000197451 "Heterogeneous nuclear ribonucleoprotein A/B" Q99729 5 178204533-178211163 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046688 Approved Enhanced Nucleoplasm NA NA 460000 "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA046688: AB_10964924" "unprognostic (2.23e-1)" "unprognostic (6.21e-2)" "unprognostic (2.61e-2)" "unprognostic (1.96e-2)" "unprognostic (8.69e-2)" "unprognostic (1.17e-1)" "unprognostic (1.22e-3)" "unprognostic (4.09e-2)" "unprognostic (6.17e-3)" "prognostic favorable (9.79e-4)" "unprognostic (9.12e-3)" "unprognostic (4.23e-2)" "prognostic unfavorable (1.35e-7)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" "unprognostic (3.53e-1)" "unprognostic (2.08e-1)" 86.7 103.2 33.2 92.5 34.9 139.7 63.9 35.6 37.0 66.0 37.3 144.7 98.2 75.5 43.8 122.0 64.4 51.1 83.1 32.4 39.1 91.9 88.3 69.1 95.7 36.9 35.4 56.7 55.4 76.2 46.2 64.0 36.9 59.8 119.0 27.1 68.1 54.0 119.0 115.4 88.9 74.4 35.5 79.9 85.5 38.2 36.9 117.0 52.0 58.7 102.7 122.3 72.7 38.5 347.4 282.5 424.1 414.7 153.8 134.6 613.2 378.5 174.3 296.9 317.2 525.4 251.8 555.2 340.3 204.7 361.1 223.2 373.1 516.7 363.8 865.9 439.5 349.8 223.7 325.1 153.7 446.1 285.6 134.0 239.2 267.3 266.8 122.3 270.3 218.4 290.1 245.7 302.0 934.2 542.6 429.7 389.5 354.0 401.7 436.3 255.6 329.8 254.2 364.8 389.5 302.4 295.2 407.9 278.8 264.0 244.7 270.7 244.0 359.7 305.2 256.2 527.8 285.4 360.2 649.3 145.2 488.2 298.8 3.2 4.4 15.7 5.1 7.0 5.7 5.9 4.1 6.0 4.4 5.2 3.9 4.7 0.8 5.8 7.5 10.9 4.8 2.2 33.2 34.9 35.6 37.0 32.4 39.1 36.9 35.4 36.9 35.5 36.9 38.5 124.7 32.1 41.0 4.6 115.4 281.6 212.1 42.7 243.0 26.5 129.6 141.3 45.9 41.5 42.7 49.7 18.8 106.3 148.5 251.2 50.9 118.9 9.3 112.4 225.6 107.1 119.2 273.2 3.5 151.7 208.9 110.1 167.7 124.7 44.5 102.0 53.6 101.2 101.0 16.8 4.3 219.0 48.8 67.0 129.9 11.1 74.0 109.9 67.6 8.4 56.2 34.7 76.2 3.5 6.1 204.2 138.2 88.0 179.6 275.0 90.5 116.8 25.8 28.3 78.9 149.7 173.6 81.6 122.4 362.5 339.8 114.4 129.7 238.1 247.9 235.5 HNRNPL HNRPL ENSG00000104824 "Heterogeneous nuclear ribonucleoprotein L" P14866 19 38836370-38852347 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016326, HPA051748, HPA052661" Supported Enhanced Nucleoplasm NA NA 420000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB016326: AB_627736, HPA051748: AB_2681588, HPA052661: AB_2681905" "unprognostic (5.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.27e-1)" "unprognostic (9.67e-3)" "unprognostic (8.99e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (3.25e-6)" "unprognostic (1.45e-1)" "unprognostic (8.85e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.57e-2)" "prognostic unfavorable (1.96e-11)" "unprognostic (2.17e-2)" "unprognostic (4.23e-2)" "unprognostic (1.58e-2)" "unprognostic (4.39e-2)" 112.5 108.5 43.8 69.7 46.1 195.1 110.3 49.4 47.4 114.0 42.9 115.2 72.7 119.9 48.0 134.4 97.6 37.4 100.2 41.8 44.5 96.6 98.8 117.7 84.2 47.0 42.9 103.8 87.5 67.7 70.6 57.6 47.5 81.5 76.4 53.2 99.8 45.7 125.7 142.3 113.4 79.9 47.2 113.5 104.3 83.7 46.9 128.8 101.7 57.3 114.5 101.9 111.6 59.4 293.6 214.8 256.4 157.9 94.8 108.7 257.7 233.3 138.9 187.1 177.4 229.9 189.7 436.8 196.2 130.5 152.1 167.0 299.6 228.9 270.7 354.4 231.0 349.9 128.3 205.9 101.2 334.0 228.2 122.7 106.9 187.1 182.1 108.8 209.4 186.7 353.7 200.0 197.6 216.0 347.7 202.9 307.6 186.6 185.6 440.8 296.4 271.7 212.1 203.8 218.6 226.0 225.1 157.7 90.0 172.2 213.4 176.7 207.1 194.9 238.1 184.2 349.4 224.0 312.5 473.1 128.4 293.1 220.0 1.2 1.9 1.2 2.6 3.0 2.0 1.7 2.0 1.7 2.6 2.2 2.0 1.7 1.9 1.8 2.5 5.1 2.6 1.1 43.8 46.1 49.4 47.4 41.8 44.5 47.0 42.9 47.5 47.2 46.9 59.4 62.2 22.4 53.8 40.1 105.1 35.4 52.1 18.0 135.5 76.7 63.6 47.6 22.9 31.5 29.1 22.0 64.6 42.9 100.0 59.0 7.9 37.4 15.9 61.2 64.8 48.7 62.9 83.3 38.0 44.1 35.3 57.0 91.7 88.4 39.3 33.8 43.5 63.0 27.4 33.7 39.0 70.4 12.2 63.7 35.1 11.7 28.3 60.3 26.6 31.9 42.4 39.0 48.4 31.2 56.3 44.1 45.6 22.6 123.0 55.6 55.4 23.9 25.5 78.7 19.7 64.1 59.0 25.5 22.1 117.6 47.5 52.3 95.0 42.4 70.2 41.9 HOMEZ KIAA1443 ENSG00000215271 "Homeobox and leucine zipper encoding" Q8IX15 14 23272422-23299447 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.4" "Group enriched" "Detected in all" 6 "Early spermatids: 309.7;Late spermatids: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036316, HPA036317" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nucleoli" "HPA036316: AB_2675056, HPA036317: AB_10669787" "unprognostic (3.70e-2)" "unprognostic (7.58e-2)" "unprognostic (6.36e-2)" "unprognostic (3.93e-2)" "unprognostic (9.11e-2)" "unprognostic (5.23e-2)" "unprognostic (1.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.37e-1)" "prognostic favorable (2.41e-5)" "unprognostic (2.23e-1)" "unprognostic (1.77e-1)" "prognostic favorable (1.17e-11)" "unprognostic (2.62e-1)" "unprognostic (2.00e-1)" "prognostic favorable (1.75e-4)" "unprognostic (3.23e-1)" 6.1 4.9 4.6 4.7 6.2 1.5 6.7 5.9 5.8 6.5 4.0 6.7 7.3 5.3 8.0 9.8 7.0 5.2 7.8 4.8 5.5 9.4 6.2 6.1 4.6 6.8 5.5 9.9 7.8 8.8 3.6 5.7 6.3 6.5 6.2 6.0 7.0 9.6 9.0 7.7 5.0 7.2 4.9 5.6 7.8 34.4 6.7 9.4 7.3 14.9 7.9 10.9 5.7 6.4 7.0 7.2 13.0 12.3 19.8 8.7 14.8 7.2 9.4 6.8 8.7 3.3 14.6 15.2 6.1 7.1 16.0 23.3 17.3 18.0 8.5 8.4 6.6 5.2 6.0 14.1 25.8 7.6 4.4 13.5 17.7 5.4 11.8 15.1 13.1 17.0 15.6 6.0 11.8 16.1 5.9 5.2 5.3 21.3 4.1 9.2 9.7 6.7 12.5 28.5 4.2 5.2 6.9 19.3 7.8 19.7 12.0 8.9 14.6 4.7 2.1 5.9 3.3 25.1 11.3 5.0 2.5 5.5 7.2 2.9 5.0 7.3 3.5 4.5 2.8 2.6 3.0 2.9 4.8 2.3 3.2 3.9 0.8 2.4 3.4 2.9 4.1 2.9 4.6 6.2 5.9 5.8 4.8 5.5 6.8 5.5 6.3 4.9 6.7 6.4 3.7 6.4 7.0 4.6 5.6 2.8 18.4 19.9 9.1 5.8 7.0 5.7 6.9 12.8 14.4 23.9 6.2 6.9 4.6 6.8 13.7 11.0 309.7 4.4 4.2 5.7 3.6 5.0 1.9 10.9 6.6 5.2 13.7 6.9 3.8 8.2 5.3 6.9 8.7 10.1 2.0 9.2 8.2 6.1 5.1 78.9 6.8 5.8 3.6 6.5 15.1 6.9 5.2 3.0 6.8 9.1 5.5 7.5 6.1 16.3 8.6 19.8 12.9 3.7 6.6 4.7 4.7 15.2 5.3 10.1 5.1 9.3 4.2 3.8 7.9 29.1 HOPX "HOP, LAGY, NECC1, OB1, SMAP31" ENSG00000171476 "HOP homeobox" Q9BPY8 4 56647988-56681899 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 716.7;skin 1: 1439.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 750.0;Alveolar cells type 2: 569.2;Basal keratinocytes: 414.6;dendritic cells: 345.3;NK-cells: 1150.4;Suprabasal keratinocytes: 377.2;Syncytiotrophoblasts: 321.8" "Cancer enhanced" "Detected in many" "glioma: 43.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 518.2;NK-cell: 781.6" "Group enriched" "Detected in all" 15 "NK-cells: 781.6;T-cells: 518.2" "Cell line enhanced" "Detected in many" "HDLM-2: 31.2;HUVEC TERT2: 66.9;RT4: 50.5;TIME: 76.2;U-266/70: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018632, HPA030180" Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear bodies" Cytosol "CAB018632: AB_2120833, HPA030180: AB_10603770" "unprognostic (2.32e-1)" "unprognostic (1.81e-2)" "unprognostic (8.03e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (1.78e-2)" "unprognostic (2.88e-1)" "unprognostic (7.79e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-5)" "unprognostic (3.40e-2)" "unprognostic (1.51e-1)" "unprognostic (7.10e-2)" "unprognostic (5.33e-2)" 9.5 33.7 212.8 27.7 235.6 12.1 112.2 215.4 322.0 250.1 239.2 30.5 17.2 19.1 541.4 716.7 10.5 35.1 48.8 237.4 212.0 24.0 2.9 372.8 18.4 237.6 211.6 9.4 5.3 13.3 11.7 59.6 218.5 26.9 7.0 22.1 172.0 64.7 19.2 1439.9 11.3 115.6 238.8 11.9 33.9 45.3 215.0 15.8 224.5 31.8 190.4 34.1 368.6 234.2 0.0 0.0 0.0 0.0 5.0 15.7 5.9 0.0 0.0 1.4 1.0 0.0 0.0 12.6 0.7 0.3 2.3 2.2 1.4 0.0 1.9 31.2 0.2 0.1 0.0 0.0 2.0 0.0 0.1 2.6 11.9 3.6 0.0 3.4 66.9 0.0 0.0 0.5 3.2 0.5 0.1 1.0 0.1 3.6 0.0 0.0 0.0 0.3 0.0 50.5 1.0 0.6 0.0 0.0 0.0 4.6 0.0 0.0 76.2 0.0 0.2 0.5 0.1 26.0 0.1 0.1 3.2 0.0 0.0 5.7 1.1 2.0 518.2 3.5 282.0 43.4 123.6 227.6 2.6 36.5 20.9 150.8 11.2 781.6 4.5 3.6 9.1 365.6 212.8 235.6 215.4 322.0 237.4 212.0 237.6 211.6 218.5 238.8 215.0 234.2 14.5 750.0 569.2 38.2 23.3 414.6 42.2 8.7 59.7 3.5 3.4 3.0 14.8 2.8 125.6 1.8 0.0 2.3 345.3 0.8 1.9 0.4 33.3 2.8 4.0 28.7 8.4 30.5 62.2 0.2 5.5 16.7 5.6 5.2 10.1 99.5 5.3 1.2 4.0 0.0 7.9 11.1 4.1 11.4 30.9 45.9 3.1 7.9 35.6 14.0 41.4 166.4 1150.4 7.1 6.7 1.7 0.0 3.0 9.6 31.3 1.2 0.6 12.5 5.6 32.9 3.7 104.8 3.3 15.3 31.6 377.2 321.8 219.9 0.1 1.4 28.8 HOXA9 "HOX1, HOX1G" ENSG00000078399 "Homeobox A9" P31269 7 27162438-27175180 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.4;skin 1: 25.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8;Endometrial stromal cells: 31.1;Enteroendocrine cells: 39.4;Proximal tubular cells: 75.1;Suprabasal keratinocytes: 27.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 6.7;myeloid DC: 5.6;NK-cell: 11.5" "Group enriched" "Detected in many" 6 "dendritic cells: 5.6;granulocytes: 6.7;NK-cells: 11.5" "Cell line enhanced" "Detected in many" "HEK 293: 124.4;PC-3: 43.9;RPTEC TERT1: 42.0;SCLC-21H: 113.4;U-937: 42.3" "Not detected" "Not detected" "HPA061982, HPA076200" Uncertain Enhanced Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA061982: AB_2684651, HPA076200: " "unprognostic (4.72e-1)" "unprognostic (1.23e-2)" "unprognostic (2.86e-1)" "unprognostic (5.24e-3)" "unprognostic (2.36e-1)" "unprognostic (2.02e-1)" "unprognostic (8.35e-2)" "unprognostic (8.44e-3)" "unprognostic (5.50e-2)" "unprognostic (5.71e-2)" "unprognostic (9.87e-3)" "unprognostic (4.42e-2)" "unprognostic (2.80e-3)" "unprognostic (6.45e-2)" "unprognostic (7.58e-2)" "unprognostic (1.92e-2)" "unprognostic (1.35e-1)" 4.7 5.9 0.0 2.8 0.0 2.5 6.9 0.0 0.2 12.7 0.0 22.0 0.0 17.0 5.6 1.0 19.6 0.0 0.0 0.0 0.0 28.4 0.0 0.4 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.8 0.1 14.1 3.9 0.0 0.0 4.5 16.1 25.7 14.8 1.9 0.2 0.9 0.2 0.0 0.0 1.9 0.1 0.0 0.0 16.8 13.8 0.2 37.7 0.0 0.0 18.4 6.0 4.4 0.0 14.6 11.7 1.2 1.2 2.4 1.4 0.3 1.4 7.9 0.0 34.7 23.5 0.0 1.2 0.0 124.4 0.3 1.1 0.0 0.6 0.0 0.5 6.0 0.0 0.0 0.0 0.0 30.6 0.0 0.0 0.0 1.2 0.0 0.0 1.2 0.0 0.0 43.9 8.1 0.0 0.0 42.0 0.7 113.4 0.0 15.6 0.0 0.3 0.6 0.0 31.3 1.4 0.0 11.4 14.0 0.2 0.0 0.0 0.0 0.0 42.3 0.0 6.7 0.8 0.0 1.3 0.2 0.2 0.1 0.0 0.1 5.6 0.9 0.2 0.0 0.8 11.5 0.3 1.8 0.2 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.2 6.2 0.0 0.0 0.0 2.0 25.1 14.9 0.0 3.4 0.0 12.2 14.7 0.5 0.0 0.0 18.4 0.0 0.2 2.9 10.5 54.8 0.0 0.0 1.0 31.1 4.3 39.4 16.6 0.0 0.0 0.3 4.8 0.0 0.6 0.0 0.0 0.7 0.0 0.3 0.0 0.0 21.7 0.0 3.4 4.2 0.0 0.0 1.9 5.4 0.0 0.8 0.0 2.1 0.0 0.0 0.0 20.2 0.0 0.9 19.4 13.3 75.1 0.0 0.0 0.0 3.0 4.6 0.0 1.0 2.6 27.6 0.3 2.2 0.3 21.4 14.2 HOXB4 "HOX2, HOX2F" ENSG00000182742 "Homeobox B4" P17483 17 48575507-48578350 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 19.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 28.5;Collecting duct cells: 64.4;Glandular and luminal cells: 25.1;Hepatic stellate cells: 24.3;NK-cells: 38.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 30 "medulla oblongata: 11.3;pons: 4.6;spinal cord: 9.1;white matter: 5.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 63.7;HMC-1: 37.5;K-562: 33.7" "Region enriched" "Detected in single" 36 "pons and medulla: 3.5" "Group enriched" "Detected in some" 13 "medulla oblongata: 3.7;spinal cord: 4.7" HPA057432 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Nucleoplasm Centrosome "HPA057432: AB_2683437" "unprognostic (2.71e-2)" "unprognostic (3.87e-2)" "unprognostic (8.97e-3)" "unprognostic (5.39e-3)" "unprognostic (1.14e-2)" "unprognostic (1.66e-1)" "unprognostic (2.65e-2)" "unprognostic (1.59e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (3.22e-2)" "unprognostic (1.14e-1)" "unprognostic (3.41e-1)" "unprognostic (2.10e-1)" "unprognostic (4.85e-2)" "unprognostic (9.25e-3)" "unprognostic (3.41e-3)" 6.9 3.1 0.1 3.7 0.0 0.7 3.5 0.0 0.1 6.8 0.1 9.8 2.6 3.4 19.6 3.4 12.8 3.3 1.0 0.0 0.0 8.7 1.1 4.6 2.3 11.3 0.2 0.3 1.2 4.4 0.0 2.6 4.6 1.0 2.4 0.0 0.3 7.6 2.6 2.5 5.1 4.3 9.1 4.4 4.3 1.2 0.2 1.9 1.0 3.9 1.4 2.9 2.2 5.8 0.3 0.5 0.0 0.2 12.2 9.2 5.2 0.0 0.0 0.8 0.4 6.2 3.1 9.2 63.7 3.3 0.7 0.3 11.8 0.0 0.2 23.3 21.5 21.9 1.6 0.0 12.5 0.0 37.5 10.0 0.0 14.9 0.0 1.2 18.4 14.6 33.7 0.6 15.1 0.0 5.5 0.2 0.0 5.8 0.0 0.0 12.3 4.5 12.5 5.4 0.0 0.0 1.7 0.0 8.7 4.2 0.5 4.3 6.0 0.4 0.5 2.2 0.4 5.0 11.9 2.1 4.3 0.0 5.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 11.3 0.2 4.6 9.1 0.2 5.8 19.9 0.0 0.0 0.0 3.0 3.8 1.3 0.0 28.5 0.0 2.7 1.7 0.9 0.0 0.0 64.4 0.0 23.5 18.4 1.0 11.7 0.2 0.2 18.5 2.7 19.0 0.0 5.0 0.0 0.0 13.1 8.2 0.5 25.1 3.8 0.0 24.3 0.2 4.0 0.0 0.0 2.3 0.0 2.8 4.4 0.2 0.3 2.1 5.4 0.0 1.3 0.0 38.1 0.0 0.0 0.0 1.9 0.0 6.6 0.5 1.0 2.0 0.7 0.0 0.0 5.9 6.4 6.0 23.2 15.5 1.8 6.0 9.9 0.1 1.8 3.1 HOXC12 "HOC3F, HOX3, HOX3F" ENSG00000123407 "Homeobox C12" P31275 12 53954903-53958956 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 14 "adipose tissue: 1.2;brain: 1.1;skin 1: 2.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.8;stomach cancer: 2.0" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 23.4;OE19: 35.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA055632 Uncertain NA NA "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "HPA055632: AB_2682867" "unprognostic (6.95e-2)" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.37e-2)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (1.17e-3)" "unprognostic (3.84e-2)" "unprognostic (2.55e-1)" 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 23.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.6 0.0 0.0 0.0 0.0 35.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 1.1 0.2 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HOXD3 "HOX1D, HOX4, HOX4A" ENSG00000128652 "Homeobox D3" P31249 2 176136612-176173102 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 42.1" "Cell type enhanced" "Detected in some" "Adipocytes: 6.6;Collecting duct cells: 9.2;Distal tubular cells: 15.6;Early spermatids: 14.4;Endothelial cells: 6.5;Theca cells: 4.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.2" "Group enriched" "Detected in many" 8 "medulla oblongata: 8.9;pons: 5.7;spinal cord: 5.7;white matter: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 9.7;HSkMC: 11.2;RPTEC TERT1: 12.0;SCLC-21H: 14.5;SH-SY5Y: 10.1" "Region enriched" "Detected in single" 35 "pons and medulla: 3.5" "Group enriched" "Detected in some" 6 "medulla oblongata: 4.1;pons: 1.1;spinal cord: 3.0" "HPA051831, HPA063671" Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA051831: , HPA063671: AB_2685083" "unprognostic (1.13e-1)" "unprognostic (3.28e-1)" "unprognostic (1.52e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-1)" "unprognostic (7.07e-2)" "unprognostic (1.97e-2)" "unprognostic (1.54e-2)" "unprognostic (9.56e-2)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (2.57e-4)" "unprognostic (1.47e-3)" "unprognostic (1.55e-1)" "unprognostic (3.44e-1)" "unprognostic (7.44e-2)" 3.2 2.3 0.2 0.8 0.4 0.0 2.8 0.4 0.3 3.2 0.1 1.0 0.3 6.9 42.1 0.7 6.8 0.6 0.2 0.2 0.4 7.9 0.0 0.2 0.8 8.9 0.8 5.5 0.2 0.1 0.0 0.1 5.7 1.7 0.6 0.0 0.5 7.1 0.7 0.9 0.8 4.1 5.7 0.7 0.3 1.7 0.4 0.2 0.4 0.0 0.2 1.0 2.0 4.9 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 1.7 0.2 0.0 0.4 0.0 0.0 0.1 3.6 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.9 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 12.0 0.9 14.5 10.1 0.2 0.1 4.6 0.2 0.0 0.0 1.0 0.2 0.2 1.5 0.8 0.0 0.2 0.0 0.5 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.3 0.2 0.4 8.9 0.8 5.7 5.7 0.4 4.9 6.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.3 15.6 0.0 14.4 0.1 2.1 6.5 1.2 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.8 3.5 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 0.3 4.5 0.0 0.1 0.3 2.9 0.0 0.0 0.0 1.3 1.1 0.8 0.5 0.0 1.3 0.0 0.1 4.7 0.6 0.1 HOXD4 "HOX4, HOX4B" ENSG00000170166 "Homeobox D4" P09016 2 176151550-176153226 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 24.4;epididymis: 28.0" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Collecting duct cells: 16.5;Early spermatids: 3.7;Endothelial cells: 3.6;Leydig cells: 4.7;Proximal tubular cells: 6.5;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 5.3" "Group enriched" "Detected in many" 21 "medulla oblongata: 10.6;pons: 5.6;spinal cord: 8.1;white matter: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 16.6;HEK 293: 39.7;RPTEC TERT1: 29.6;SK-MEL-30: 11.0" "Region enriched" "Detected in single" 46 "pons and medulla: 4.5" "Group enriched" "Detected in some" 4 "medulla oblongata: 6.0;spinal cord: 7.8" "HPA054383, HPA070349" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Cell Junctions" "HPA054383: AB_2682470, HPA070349: AB_2686258" "unprognostic (9.37e-2)" "unprognostic (1.54e-1)" "unprognostic (1.03e-3)" "unprognostic (1.10e-3)" "unprognostic (9.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.19e-2)" "unprognostic (6.69e-3)" "unprognostic (1.66e-1)" "unprognostic (3.47e-1)" "unprognostic (1.49e-1)" "unprognostic (2.50e-1)" "unprognostic (7.78e-2)" "unprognostic (1.12e-2)" "unprognostic (9.93e-2)" "unprognostic (5.81e-2)" "unprognostic (1.61e-1)" 6.9 8.3 0.0 1.6 0.0 0.0 7.4 0.0 0.1 7.1 0.0 7.3 1.0 24.4 28.0 1.1 14.3 1.5 0.6 0.0 0.0 18.5 0.0 0.4 1.7 10.6 0.3 15.1 0.6 0.1 0.0 0.4 5.6 2.9 2.0 0.0 0.7 11.1 2.8 2.4 6.2 9.7 8.1 7.2 1.0 3.0 0.0 0.2 1.2 0.5 0.4 2.7 4.0 7.3 0.5 0.3 0.0 0.0 2.0 3.0 0.0 0.2 0.9 0.1 1.1 0.9 0.0 0.0 16.6 3.4 0.7 0.2 2.6 0.0 0.4 0.0 39.7 0.5 0.0 0.0 0.5 0.0 0.1 9.3 2.6 0.0 0.5 0.2 6.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 29.6 4.1 2.5 4.2 0.6 0.0 11.0 0.6 0.0 0.0 5.0 0.5 0.2 2.9 2.1 0.0 0.1 0.0 2.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.3 5.6 8.1 0.0 7.3 5.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 3.7 0.1 1.1 3.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.7 2.6 4.7 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 3.0 0.0 0.1 0.3 6.5 0.0 0.0 6.6 0.6 0.9 0.3 0.4 0.0 0.6 0.0 0.1 3.0 1.3 0.0 HOXD8 "HOX4, HOX4E" ENSG00000175879 "Homeobox D8" P13378 2 176129694-176132695 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 99.6;kidney: 76.2" "Cell type enhanced" "Detected in many" "Adipocytes: 51.8;Collecting duct cells: 60.7;Distal tubular cells: 213.2;Early spermatids: 124.6;Leydig cells: 51.3;Peritubular cells: 53.8;Spermatocytes: 82.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "medulla oblongata: 1.5;spinal cord: 4.0;white matter: 5.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 45.4;RPTEC TERT1: 74.8;TIME: 32.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 70 "spinal cord: 34.6" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.22e-1)" "unprognostic (6.31e-2)" "unprognostic (2.19e-3)" "unprognostic (2.68e-2)" "unprognostic (3.35e-1)" "unprognostic (3.49e-1)" "unprognostic (2.56e-3)" "prognostic unfavorable (3.78e-4)" "unprognostic (2.79e-1)" "unprognostic (1.40e-2)" "unprognostic (3.93e-1)" "unprognostic (3.05e-1)" "unprognostic (3.63e-2)" "unprognostic (4.80e-2)" "unprognostic (5.21e-2)" "unprognostic (8.31e-2)" "unprognostic (2.80e-2)" 16.4 20.6 0.0 4.8 0.0 0.0 18.8 0.0 0.0 13.3 0.0 10.8 1.2 19.5 99.6 2.7 17.2 3.1 0.9 0.0 0.0 76.2 0.3 0.9 4.9 1.5 0.0 34.2 1.4 1.1 0.0 0.7 0.8 6.0 4.9 0.0 1.7 24.0 7.8 4.8 8.6 13.1 4.0 10.5 1.6 20.1 0.0 1.0 3.5 1.5 1.3 6.5 9.2 5.8 13.7 2.1 0.0 0.0 8.8 14.1 0.3 1.7 7.2 2.2 0.2 0.1 0.1 0.0 16.7 10.8 1.7 0.1 4.7 0.5 5.4 0.0 6.4 2.3 0.8 0.0 2.9 1.3 0.8 24.7 45.4 0.3 6.7 0.0 22.9 4.4 0.2 0.1 3.7 0.1 0.1 0.4 0.2 0.0 2.6 0.0 4.9 0.2 74.8 9.6 14.2 26.4 4.3 0.0 28.4 1.2 0.0 0.1 32.5 1.1 8.9 15.4 9.1 0.0 0.0 0.0 21.1 0.0 26.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 4.0 0.0 5.8 51.8 0.0 1.1 0.0 0.5 2.7 2.1 0.0 0.6 0.0 0.7 0.6 2.3 0.0 0.0 60.7 0.0 0.0 0.2 2.7 213.2 0.0 124.6 0.7 9.4 36.4 4.8 0.0 0.0 0.0 0.0 14.9 0.0 0.3 0.0 0.0 2.5 0.0 0.1 0.0 0.0 1.8 0.0 0.0 3.4 29.9 51.3 0.5 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 53.8 0.0 1.3 0.5 25.1 0.7 0.0 32.9 14.1 9.8 82.1 20.4 0.2 2.8 0.1 1.0 31.9 3.4 1.1 HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 235.0;urinary bladder: 376.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 457.8;Extravillous trophoblasts: 701.7;granulocytes: 864.5;Proximal enterocytes: 500.6;Urothelial cells: 922.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 123.7;T-reg: 45.0" "Group enriched" "Detected in many" 73 "granulocytes: 123.7;T-cells: 45.0" "Cell line enhanced" "Detected in many" "A549: 157.8;ASC diff: 110.6;HEL: 355.0;OE19: 102.1;RT4: 565.7;SuSa: 121.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 20000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favorable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" 9.2 16.5 1.0 11.4 0.7 2.7 159.9 0.5 1.2 32.2 8.7 60.9 152.2 45.5 36.5 81.6 13.4 24.9 1.6 1.2 2.8 60.2 210.8 91.0 5.5 1.4 2.0 1.1 2.6 85.3 2.1 99.1 1.0 10.2 57.4 1.0 7.7 4.0 2.5 39.8 117.3 63.7 0.8 10.3 235.0 1.6 2.2 12.2 1.7 3.0 26.6 376.0 83.0 0.7 0.0 157.8 0.0 0.0 110.6 5.4 0.4 0.0 0.0 0.0 0.4 45.1 0.2 0.1 0.0 0.0 0.2 14.2 16.0 0.0 0.0 0.3 2.9 355.0 10.8 0.3 0.0 2.1 0.9 5.6 2.6 0.0 0.1 0.1 0.0 22.6 0.2 0.0 0.0 0.3 1.2 0.3 1.4 102.1 7.4 16.3 0.3 1.3 36.2 565.7 0.9 0.4 0.0 1.3 3.5 121.3 0.1 0.0 0.3 0.0 0.2 0.1 0.0 28.4 0.0 0.1 0.3 0.2 0.0 123.7 0.3 16.6 9.9 0.0 15.6 0.4 5.2 4.5 0.7 0.2 1.6 4.0 1.3 1.1 0.0 0.0 45.0 3.0 1.0 0.7 0.5 1.2 1.2 2.8 1.4 2.0 1.0 0.8 2.2 0.7 3.4 16.0 33.0 0.0 4.3 17.3 80.8 6.9 45.5 3.3 14.5 6.7 0.8 35.8 23.6 22.0 0.0 48.5 38.5 457.8 21.5 7.4 1.4 5.7 5.4 18.2 8.4 17.2 0.8 94.5 701.7 25.3 196.7 36.4 864.5 1.5 13.9 245.7 21.4 0.0 9.7 60.7 0.0 14.8 19.5 0.5 19.9 29.2 76.5 5.6 2.9 0.0 10.3 0.0 4.1 42.4 254.7 0.0 50.2 76.8 500.6 131.1 4.4 0.8 0.0 2.4 3.7 0.5 1.0 53.4 22.4 56.6 42.7 65.0 58.9 922.8 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 200.5;liver: 866.2;pancreas: 272.1" "Group enriched" "Detected in many" 6 "Hepatocytes: 442.2;Proximal tubular cells: 201.0" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "EFO-21: 31.5;Hep G2: 47.8;T-47d: 22.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 1.8 0.9 5.6 0.2 8.8 0.0 11.6 7.0 7.2 1.6 4.2 1.1 1.4 4.0 3.9 0.3 7.4 4.0 5.1 5.7 6.5 200.5 866.2 11.8 0.4 7.5 8.1 1.3 272.1 24.2 14.8 0.5 7.5 20.1 0.3 0.3 15.6 4.7 22.1 0.9 1.1 0.2 6.5 2.6 58.2 1.3 7.6 0.2 19.9 5.4 0.1 0.6 0.4 11.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.5 0.0 0.1 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.3 0.1 0.0 0.0 3.2 0.2 0.1 0.0 0.2 0.5 22.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.8 7.0 7.2 5.7 6.5 7.5 8.1 7.5 6.5 7.6 11.7 0.5 9.6 32.4 8.8 3.0 0.1 5.1 0.0 0.0 7.2 12.0 8.9 3.4 51.5 1.3 33.1 0.0 0.1 0.0 0.1 52.8 7.5 8.9 4.9 1.0 1.1 2.4 10.7 2.3 26.5 0.3 1.9 18.3 12.5 2.5 0.1 8.6 442.2 1.1 0.0 1.7 2.4 0.0 9.7 0.3 26.0 0.0 1.8 0.0 2.8 0.6 1.6 0.0 0.0 41.6 14.4 0.0 0.4 0.0 7.5 0.0 201.0 0.0 0.6 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.8 1.8 0.1 0.1 0.5 HRH4 "AXOR35, GPCR105, GPRv53, H4R, HH4R" ENSG00000134489 "Histamine receptor H4" Q9H3N8 18 24460637-24479961 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Club cells: 1.3;Early spermatids: 1.2;granulocytes: 1.3;Late spermatids: 1.3;Melanocytes: 1.8;Spermatocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 123 "basophil: 212.9;eosinophil: 61.1" "Lineage enriched" "Detected in many" 191 "granulocytes: 212.9" "Cell line enhanced" "Detected in single" "HL-60: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035009 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA035009: AB_10671507" "unprognostic (1.88e-1)" "unprognostic (2.62e-1)" "unprognostic (4.68e-2)" "unprognostic (9.83e-6)" "unprognostic (1.31e-2)" "unprognostic (3.61e-2)" "unprognostic (1.22e-1)" "unprognostic (8.96e-2)" "unprognostic (2.20e-1)" "unprognostic (3.30e-1)" "unprognostic (7.25e-2)" "unprognostic (2.91e-1)" "unprognostic (6.65e-7)" "unprognostic (1.89e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-4)" "unprognostic (7.70e-2)" 0.1 0.1 0.2 0.4 0.1 0.8 0.0 0.3 0.3 0.1 0.3 0.1 0.5 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.3 0.6 0.5 0.1 0.0 0.3 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.2 0.0 1.3 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.1 212.9 0.1 61.1 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.2 0.5 0.5 0.2 0.1 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.3 0.2 0.0 0.6 0.3 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.3 0.4 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.3 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.7 1.3 0.0 0.1 1.8 1.0 0.0 0.3 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.0 0.8 0.3 1.3 0.3 0.0 0.6 0.0 0.5 0.2 0.0 0.4 HS3ST4 3OST4 ENSG00000182601 "Heparan sulfate-glucosamine 3-sulfotransferase 4" Q9Y661 16 25691959-26137685 "Enzymes, Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 38.1" "Group enriched" "Detected in some" 9 "Excitatory neurons: 431.4;Microglial cells: 536.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.09e-2)" "unprognostic (1.87e-1)" "unprognostic (2.95e-1)" "unprognostic (2.24e-1)" "unprognostic (1.43e-3)" "unprognostic (1.27e-1)" "unprognostic (3.84e-1)" "unprognostic (8.81e-3)" "unprognostic (6.71e-2)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.51e-2)" "unprognostic (3.67e-2)" 0.0 0.0 19.0 0.0 17.5 0.0 2.2 7.0 15.8 0.3 3.3 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 33.2 12.2 0.0 0.0 0.0 0.0 18.2 11.8 0.0 0.0 3.6 0.3 0.0 19.0 0.8 0.0 2.0 0.1 0.0 0.0 0.5 0.0 0.0 7.5 1.6 1.7 0.5 38.1 0.2 0.0 0.0 0.0 0.2 0.5 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 17.5 7.0 15.8 33.2 12.2 18.2 11.8 19.0 7.5 38.1 18.5 0.0 0.0 0.0 7.5 0.1 0.0 0.4 0.1 0.0 26.0 2.6 2.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 431.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 536.8 0.0 0.4 0.0 6.6 9.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 HS3ST6 HS3ST5 ENSG00000162040 "Heparan sulfate-glucosamine 3-sulfotransferase 6" Q96QI5 16 1911475-1918415 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 75.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 10.7;Horizontal cells: 21.9;Suprabasal keratinocytes: 9.1;Urothelial cells: 24.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "A549: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.72e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-1)" "unprognostic (4.99e-3)" "unprognostic (2.10e-2)" "unprognostic (6.55e-3)" "unprognostic (2.42e-1)" "unprognostic (3.61e-1)" "unprognostic (2.26e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.5 0.0 0.0 0.0 14.4 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 1.4 0.0 0.0 1.9 0.0 0.3 75.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.1 4.1 10.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 3.4 0.9 0.0 0.0 0.1 0.0 0.3 0.0 0.7 1.8 0.0 0.2 0.0 6.3 0.0 0.0 4.5 10.7 0.5 0.1 0.0 0.0 0.1 0.0 0.4 2.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 21.9 0.1 0.9 4.1 0.0 1.5 1.4 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.0 0.0 2.7 0.2 0.2 5.0 0.2 0.0 0.0 0.3 0.0 0.0 4.5 9.1 0.1 0.1 0.0 1.7 24.9 HSD17B6 "HSE, RODH, SDR9C6" ENSG00000025423 "Hydroxysteroid 17-beta dehydrogenase 6" O14756 12 56752161-56787790 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "liver: 1804.3" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1969.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 170.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 13.4;U-266/84: 18.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059141 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Vesicles" "HPA059141: AB_2683922" "unprognostic (7.70e-2)" "unprognostic (8.76e-2)" "unprognostic (5.08e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-2)" "prognostic favorable (6.32e-4)" "unprognostic (1.06e-2)" "unprognostic (3.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (2.50e-10)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" 8.5 2.5 13.1 6.9 16.2 0.5 0.7 13.4 18.9 28.0 9.4 24.7 3.2 20.9 1.6 9.9 6.5 9.1 0.8 12.3 12.6 2.5 1804.3 63.2 0.8 12.0 14.6 6.0 0.6 0.5 0.6 5.4 11.5 51.2 7.6 0.8 0.4 69.2 0.4 1.2 4.8 13.1 12.4 47.5 5.7 23.3 13.7 0.9 31.4 0.5 0.9 36.7 14.6 12.8 0.3 0.8 1.9 0.4 1.9 1.4 2.3 4.1 3.5 1.9 1.9 0.4 0.4 12.0 1.7 0.5 0.5 0.3 6.1 1.1 1.1 7.7 2.2 3.7 1.2 0.6 1.2 1.9 6.0 1.0 0.4 1.2 0.6 0.6 0.0 10.3 1.1 13.4 0.9 2.4 5.6 1.3 7.5 0.7 0.7 7.4 0.8 2.9 0.2 1.4 11.0 2.3 2.0 3.6 0.9 0.7 0.6 1.5 0.3 0.9 0.8 4.0 1.0 11.7 18.0 7.8 1.3 6.9 0.6 0.0 0.0 0.0 1.0 0.2 1.2 0.7 0.8 0.8 0.2 0.3 1.1 0.7 0.0 0.0 0.5 0.7 1.0 0.3 13.1 16.2 13.4 18.9 12.3 12.6 12.0 14.6 11.5 12.4 13.7 12.8 0.4 173.1 130.6 21.2 6.1 1.3 3.1 0.6 0.6 0.4 0.7 0.6 0.2 27.1 9.3 0.0 0.0 1.4 0.4 0.0 0.0 0.1 4.6 0.7 3.5 1.3 0.0 29.5 1.4 0.0 2.6 5.0 0.0 0.1 0.0 1.6 26.0 1969.3 0.4 0.0 2.1 0.4 0.0 40.2 0.3 4.5 12.5 0.5 0.0 1.0 1.0 1.3 0.0 3.0 5.5 0.1 0.0 1.5 0.8 16.1 0.0 0.3 1.5 0.6 13.1 0.6 3.5 16.4 11.4 1.2 1.6 0.4 2.2 36.0 0.7 1.1 HSD17B8 "D6S2245E, FABGL, H2-KE6, HKE6, KE6, RING2, SDR30C1" ENSG00000204228 "Hydroxysteroid 17-beta dehydrogenase 8" Q92506 6 33204655-33206831 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 125.2;Proximal tubular cells: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 79.5;T-47d: 62.0;U-266/70: 65.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042132 Enhanced NA NA 97000 "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA042132: AB_10793978" "prognostic favorable (9.99e-4)" "unprognostic (4.24e-1)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (2.10e-1)" "unprognostic (8.11e-2)" "prognostic favorable (1.90e-5)" "unprognostic (1.50e-3)" "unprognostic (3.12e-1)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (1.89e-1)" "prognostic favorable (2.18e-12)" "unprognostic (2.82e-2)" "unprognostic (5.57e-1)" "unprognostic (3.09e-1)" "unprognostic (3.23e-2)" 9.6 24.6 10.1 6.5 10.5 9.7 17.0 9.9 11.3 13.7 10.9 18.0 19.7 7.2 29.4 25.5 23.6 7.9 20.3 9.6 10.8 30.7 67.4 11.2 10.5 11.3 11.9 8.6 55.3 42.2 14.1 5.6 12.3 11.3 16.2 11.8 25.1 16.5 20.8 25.9 18.8 7.3 11.4 12.1 15.1 5.9 10.8 13.3 32.9 25.0 15.1 9.8 12.8 11.3 7.0 15.0 6.8 9.3 2.3 4.4 1.3 0.8 4.7 0.1 0.1 5.8 17.5 45.4 11.2 1.2 2.2 29.1 7.2 11.7 1.0 8.6 0.0 2.6 14.0 27.1 20.0 0.0 3.8 5.0 28.9 0.2 49.4 0.4 2.1 13.6 0.3 46.2 4.1 9.4 31.2 1.3 2.1 23.3 2.9 11.0 1.2 79.5 27.8 1.3 12.1 7.6 2.9 34.3 7.6 4.6 62.0 1.8 1.3 0.7 7.3 0.6 0.4 65.5 42.4 16.6 3.1 1.0 1.7 0.1 5.8 2.0 18.7 13.4 30.0 16.6 24.0 29.2 11.6 13.1 26.4 28.5 0.7 16.8 14.6 20.8 21.8 26.7 10.1 10.5 9.9 11.3 9.6 10.8 11.3 11.9 12.3 11.4 10.8 11.3 12.5 19.2 21.6 3.3 18.6 29.7 28.3 55.0 21.6 12.4 31.3 34.8 31.8 48.6 25.9 22.0 6.2 29.9 9.7 21.2 125.2 27.9 6.3 20.0 6.0 10.1 18.0 12.8 0.3 32.4 12.9 9.1 16.3 13.7 7.0 9.8 10.0 83.2 17.4 1.7 0.5 26.6 20.3 10.3 16.4 18.1 7.5 7.9 49.8 1.0 8.1 32.6 6.2 1.0 0.7 21.9 21.1 6.0 47.6 15.4 74.8 137.2 33.3 14.8 0.0 11.3 9.8 8.1 8.5 40.0 37.2 17.4 18.0 29.8 44.4 31.5 HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 77.7" "Group enriched" "Detected in some" 8 "Extravillous trophoblasts: 140.8;Syncytiotrophoblasts: 502.0" "Cancer enriched" "Detected in single" 4 "urothelial cancer: 1.6" "Region enhanced" "Detected in some" "basal ganglia: 1.0;cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 64.1;SuSa: 26.5" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Cytokinetic bridge" Yes NA "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoli, Endoplasmic reticulum" "Cytokinetic bridge" "HPA043261: AB_2630368, HPA043264: AB_2678398, HPA044028: AB_2678781" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.04e-1)" "prognostic favorable (4.59e-5)" 0.1 1.2 0.2 0.0 1.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 77.7 0.0 0.1 0.5 0.0 0.1 0.0 0.1 4.5 8.7 0.5 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.0 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 7.0 0.7 0.8 26.5 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 23.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 140.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 502.0 0.0 0.1 1.0 0.0 HSF2BP MEILB2 ENSG00000160207 "Heat shock transcription factor 2 binding protein" O75031 21 43529186-43659488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "testis: 24.1" "Group enriched" "Detected in many" 7 "Early spermatids: 125.5;Late spermatids: 49.0;Spermatocytes: 132.4;Spermatogonia: 63.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 12.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031724, HPA075775" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Cytosol "HPA031724: AB_10601022, HPA075775: " "unprognostic (1.91e-2)" "unprognostic (1.19e-1)" "unprognostic (7.27e-3)" "unprognostic (1.54e-4)" "unprognostic (2.62e-1)" "unprognostic (1.78e-2)" "unprognostic (9.36e-4)" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (4.55e-2)" "unprognostic (1.79e-1)" "unprognostic (3.11e-1)" "unprognostic (1.44e-2)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (8.77e-4)" "unprognostic (6.00e-2)" 0.3 0.3 0.4 0.1 0.5 0.1 0.5 0.3 0.9 0.5 0.3 0.3 0.2 0.6 0.5 0.3 0.6 0.2 0.4 1.3 0.7 0.5 0.2 0.2 0.3 0.5 0.5 0.7 0.2 0.8 0.8 0.9 0.6 0.4 0.2 0.9 0.4 0.4 0.2 0.4 0.2 0.2 0.3 0.2 0.2 24.1 0.7 0.1 0.5 0.1 0.2 0.3 0.4 0.7 4.6 0.9 1.2 0.5 0.2 1.1 1.1 1.6 0.9 1.6 1.4 6.1 4.5 3.5 2.4 0.9 5.7 1.8 0.6 12.8 0.5 0.9 1.1 0.6 1.9 0.3 1.4 1.5 0.4 0.7 8.2 0.7 3.8 7.5 0.4 2.0 1.3 1.1 3.9 0.8 2.0 1.4 3.9 1.1 1.9 2.9 1.2 0.5 2.0 0.8 1.3 1.0 3.3 1.6 1.7 0.5 1.7 1.7 2.6 0.9 3.0 0.2 2.4 1.2 0.9 2.8 0.8 3.0 2.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.3 0.0 0.3 0.7 0.7 0.0 0.4 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.9 1.3 0.7 0.5 0.5 0.6 0.3 0.7 0.7 0.2 0.0 0.0 2.6 0.1 0.9 1.5 4.7 2.8 1.0 1.3 1.7 0.7 0.0 2.0 0.0 0.0 1.8 0.2 0.2 0.0 1.1 125.5 0.5 1.4 0.5 0.0 0.0 3.0 0.2 2.8 2.1 0.0 0.4 0.0 2.4 0.4 0.3 0.7 0.0 1.7 0.1 0.0 0.0 0.7 49.0 1.8 0.5 0.0 0.0 0.0 2.1 0.0 3.0 4.4 2.7 0.3 1.5 0.0 0.8 0.0 1.1 2.8 2.5 13.1 0.5 0.9 132.4 63.1 0.6 0.4 0.8 0.2 3.8 0.3 1.0 HSPB1 "CMT2F, Hs.76067, Hsp25, HSP27, HSP28" ENSG00000106211 "Heat shock protein family B (small) member 1" P04792 7 76302673-76304295 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" Chaperone "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 5909.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 16589.4;Exocrine glandular cells: 6539.7;Squamous epithelial cells: 6300.1;Urothelial cells: 13091.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 2482.8;MCF7: 3979.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000497, CAB004439, CAB047330, CAB047331, CAB047332" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 19000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "CAB004439: AB_627755, CAB047330: , CAB047331: , CAB047332: , HPA000497: AB_1851172" "unprognostic (2.55e-1)" "unprognostic (7.25e-3)" "prognostic unfavorable (9.94e-5)" "unprognostic (7.07e-3)" "unprognostic (3.47e-3)" "unprognostic (6.61e-3)" "unprognostic (4.08e-3)" "unprognostic (4.50e-2)" "unprognostic (1.27e-1)" "unprognostic (9.78e-2)" "unprognostic (8.70e-2)" "unprognostic (2.21e-1)" "unprognostic (5.72e-2)" "unprognostic (5.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.56e-1)" "unprognostic (3.63e-1)" 964.4 856.4 810.6 329.6 835.1 52.3 560.5 821.6 1798.8 2123.4 864.3 2043.6 208.7 2824.2 131.7 5909.6 993.8 217.2 2981.9 776.6 944.5 986.4 554.9 790.9 99.0 894.1 838.7 731.6 751.7 221.1 303.3 324.3 870.8 979.0 73.8 10.2 1075.3 522.5 3669.8 2258.3 523.8 1066.9 808.2 224.5 770.3 99.8 840.0 218.7 627.1 628.1 279.3 1579.4 3398.4 869.5 1251.1 902.4 79.5 576.8 487.3 447.5 5.1 514.9 249.8 260.9 325.8 84.8 660.7 8.5 389.1 599.1 514.1 1094.2 359.0 279.6 76.5 690.9 106.4 41.5 611.4 345.5 267.9 69.9 466.5 542.8 2482.8 370.0 50.5 436.6 831.3 169.5 459.4 1079.7 276.5 3979.7 117.1 508.9 407.4 212.7 800.6 417.3 195.8 974.5 342.8 423.2 7.6 529.1 363.8 1323.3 456.0 224.5 1674.9 551.6 504.2 778.8 1200.3 221.7 1310.1 85.7 145.9 10.7 575.9 247.2 579.5 19.7 13.6 10.9 58.8 78.2 28.1 115.0 92.4 62.1 31.5 105.5 102.1 88.2 5.8 79.7 112.8 56.5 64.5 46.7 810.6 835.1 821.6 1798.8 776.6 944.5 894.1 838.7 870.8 808.2 840.0 869.5 708.2 272.4 186.4 78.4 145.4 1849.8 16589.4 3603.0 1728.4 243.4 312.5 174.4 822.3 264.5 1899.4 1144.0 323.2 161.7 62.0 824.2 1500.7 2021.4 11.9 1181.8 1060.9 1038.7 422.0 136.1 4.3 6539.7 399.4 998.5 219.2 1227.1 216.7 136.3 725.7 234.7 1199.8 70.7 2.2 433.0 1245.1 147.7 2828.9 30.8 299.5 1024.8 2056.2 35.6 188.0 171.4 50.4 8.0 2.7 2719.4 1417.1 534.5 296.9 3854.8 95.3 2324.4 1253.9 29.2 611.4 551.2 2129.1 20.3 105.5 6300.1 2241.7 2432.7 758.2 68.2 390.5 13091.2 HSPB8 "CMT2L, E2IG1, H11, HSP22" ENSG00000152137 "Heat shock protein family B (small) member 8" Q9UJY1 12 119171555-119224855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" Chaperone "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 897.3" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 599.1;Syncytiotrophoblasts: 1340.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 89.6;HeLa: 66.0;MCF7: 130.5;U-87 MG: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015876 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol Nucleoplasm "HPA015876: AB_1850458" "unprognostic (1.52e-2)" "unprognostic (6.97e-2)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.47e-1)" "unprognostic (4.03e-2)" "unprognostic (7.91e-2)" "unprognostic (6.48e-3)" "unprognostic (1.11e-1)" "unprognostic (1.30e-1)" "unprognostic (2.05e-3)" "unprognostic (2.05e-1)" "unprognostic (6.36e-2)" "unprognostic (2.17e-2)" 57.0 13.9 172.2 34.4 172.6 0.0 33.4 179.5 141.8 58.1 147.0 381.0 8.9 114.4 10.1 163.2 58.7 43.1 469.3 147.8 231.0 63.3 4.8 95.7 11.4 188.3 206.1 23.4 30.8 183.1 17.5 92.1 193.0 143.5 35.8 28.2 50.8 289.0 897.3 70.5 50.5 114.1 211.5 56.2 110.4 12.0 193.6 40.3 29.2 448.5 98.7 239.2 100.1 235.5 21.1 16.1 0.3 0.0 14.4 11.5 60.2 32.5 28.7 5.9 0.3 40.0 0.6 0.1 89.6 42.4 48.0 2.4 0.3 0.0 0.6 0.1 1.2 0.0 66.0 3.2 11.2 0.0 0.1 14.1 4.1 22.3 1.3 21.6 12.3 0.0 0.2 0.0 13.0 130.5 0.0 0.2 5.7 0.0 23.0 0.0 22.9 2.9 38.3 6.2 0.4 1.0 13.5 1.6 6.8 50.5 29.0 0.2 20.4 15.8 39.8 21.7 1.7 0.0 0.2 0.2 67.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 172.2 172.6 179.5 141.8 147.8 231.0 188.3 206.1 193.0 211.5 193.6 235.5 2.7 44.8 48.2 42.1 0.7 102.3 108.5 4.5 126.3 0.7 95.2 17.5 599.1 7.2 5.4 5.5 8.4 149.1 1.0 0.0 0.0 59.7 12.2 98.1 20.2 27.4 0.0 0.0 6.2 11.4 17.5 82.2 5.6 142.7 1.3 0.0 25.4 0.0 19.4 1.7 6.6 0.0 2.0 1.0 9.4 11.0 1.5 1.6 12.4 2.8 1.0 51.7 0.0 0.0 0.9 12.9 0.0 0.4 0.3 24.6 0.0 52.0 3.1 2.1 6.6 39.8 76.9 0.9 0.2 38.0 28.7 1340.0 3.5 0.1 0.2 72.7 HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 201.6;lymphoid tissue: 95.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Hepatic stellate cells: 33.2;Hepatocytes: 137.1;Proximal tubular cells: 58.2" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 100.9;SK-BR-3: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" NA NA 590000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" 11.4 21.5 5.0 2.8 4.5 0.3 9.2 6.4 6.3 10.8 18.3 6.8 3.4 8.2 0.8 5.5 7.3 13.2 68.2 4.5 4.0 49.4 201.6 30.7 1.8 5.4 4.8 3.0 9.4 19.9 3.3 2.4 5.6 4.6 2.9 3.1 7.3 2.9 15.0 21.1 6.0 5.9 3.5 95.1 19.4 1.7 5.8 0.8 8.3 19.0 1.2 4.8 12.3 4.7 2.9 1.8 0.4 0.9 0.6 0.7 0.5 0.1 0.3 0.1 0.4 11.4 3.1 0.0 0.8 0.6 0.6 6.6 0.2 0.4 0.0 0.1 0.0 0.3 8.6 100.9 4.4 0.7 0.7 3.9 13.8 0.1 0.4 0.8 2.9 0.3 0.3 0.5 0.4 0.6 0.1 0.3 0.6 7.1 0.6 0.0 0.2 0.3 5.9 0.4 0.2 2.1 0.2 28.0 0.3 2.4 2.0 0.3 1.9 0.6 0.6 0.6 0.3 0.2 0.3 0.4 0.4 0.6 0.3 1.3 0.4 1.5 0.3 0.1 0.8 0.4 0.3 0.4 0.2 0.5 0.6 0.4 3.1 0.3 0.3 0.5 0.4 0.1 5.0 4.5 6.4 6.3 4.5 4.0 5.4 4.8 5.6 3.5 5.8 4.7 18.1 19.2 18.5 1.6 0.3 2.9 0.4 3.3 0.0 1.0 0.3 0.1 20.8 30.0 2.0 11.0 4.2 0.1 0.0 2.5 23.5 16.5 8.2 0.2 0.9 25.8 1.8 2.7 3.1 14.4 0.1 3.3 19.4 0.2 0.0 0.6 33.2 137.1 0.1 0.0 3.1 1.4 0.0 4.4 0.9 7.7 2.1 0.9 0.0 7.5 0.0 0.4 0.0 1.5 1.6 12.1 0.3 1.2 0.0 0.2 0.4 58.2 0.9 0.5 6.6 1.2 4.3 0.4 1.1 0.9 3.1 0.7 0.9 7.4 0.9 1.7 HYAL4 ENSG00000106302 "Hyaluronidase 4" Q2M3T9 7 123828983-123877481 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 4.0;skeletal muscle: 3.9" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.8;Cytotrophoblasts: 4.3;Extravillous trophoblasts: 8.1;Spermatogonia: 4.4;Syncytiotrophoblasts: 2.2" "Cancer enriched" "Detected in single" 48 "testis cancer: 8.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;CAPAN-2: 5.9;RT4: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA029453 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA029453: AB_10601432" "unprognostic (5.19e-5)" "unprognostic (4.18e-2)" "unprognostic (4.82e-2)" "unprognostic (2.20e-1)" "unprognostic (4.14e-2)" "unprognostic (2.60e-1)" "unprognostic (8.24e-2)" "unprognostic (5.26e-2)" "unprognostic (8.15e-3)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (5.55e-3)" 0.1 0.1 0.6 0.0 0.7 0.5 0.1 1.0 1.0 0.1 0.5 0.2 0.0 0.1 0.4 0.4 0.0 0.1 0.2 0.7 0.4 0.4 0.1 0.4 0.2 0.5 0.3 0.2 0.5 0.0 0.0 4.0 0.7 0.2 0.1 1.0 0.5 0.2 3.9 0.9 0.2 0.0 0.1 0.8 0.2 2.1 0.5 0.0 0.4 0.0 1.0 0.2 0.0 1.3 0.2 0.4 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 5.9 0.2 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.1 0.0 13.9 0.2 0.0 0.0 0.8 0.0 1.1 0.2 0.0 2.0 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.6 0.2 0.1 0.1 0.0 0.0 0.6 0.7 1.0 1.0 0.7 0.4 0.5 0.3 0.7 0.1 0.5 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 8.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 1.3 4.4 0.0 0.0 2.2 0.0 0.0 0.0 0.2 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 12 "T-cells: 81.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Group enriched" "Detected in some" 8 "HEL: 4.6;MOLT-4: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" 0.5 0.1 0.0 7.7 0.0 16.5 0.3 0.0 0.0 0.2 0.0 0.7 0.7 0.2 0.1 0.5 0.3 1.4 0.2 0.0 0.0 0.2 0.4 2.6 14.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.2 2.3 0.4 0.0 3.3 1.3 0.2 0.0 20.2 0.4 0.0 16.2 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.2 0.0 15.1 6.8 0.0 0.0 15.7 7.2 0.1 0.5 0.0 0.0 29.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.3 0.0 3.1 2.9 0.0 0.0 0.0 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.2 6.3 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.8 4.7 0.1 0.0 3.1 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.0 1.8 0.1 81.2 0.0 0.0 0.1 IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574096 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Secreted in other tissues" NA NA 310000 "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA063478: AB_2685020" "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favorable (3.69e-4)" "prognostic favorable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" 6.7 10.1 3.4 2.8 3.6 3.5 6.1 3.7 4.2 8.1 5.9 8.6 3.3 7.4 9.7 9.8 6.5 2.9 11.7 3.4 3.7 5.9 11.4 5.9 3.4 3.8 3.7 5.4 12.3 9.5 4.7 2.7 3.9 9.1 3.8 10.3 7.8 4.2 28.8 36.4 6.8 3.7 3.6 6.3 8.2 25.8 3.6 2.4 6.7 9.7 4.1 8.9 7.9 3.8 12.1 22.9 6.2 15.1 10.5 5.8 8.5 10.4 13.3 6.1 5.2 19.4 9.5 12.5 16.4 14.3 7.2 16.3 14.6 10.0 3.9 14.7 8.8 5.1 13.7 25.9 11.5 14.9 6.5 5.4 6.6 9.1 14.0 7.8 8.6 3.3 10.0 8.1 5.4 18.0 6.6 8.8 10.2 10.4 5.2 10.2 10.8 9.0 10.9 19.3 2.2 5.6 14.3 6.4 6.7 6.8 12.6 6.3 15.3 4.4 8.2 5.0 10.4 11.2 12.2 14.5 6.9 10.9 4.4 0.3 3.5 1.4 2.0 4.2 2.2 2.9 2.6 2.9 4.6 2.1 1.9 2.0 0.0 3.7 5.9 1.3 3.9 2.3 3.4 3.6 3.7 4.2 3.4 3.7 3.8 3.7 3.9 3.6 3.6 3.8 12.9 9.6 14.1 20.9 11.1 5.2 6.1 10.5 5.2 15.0 8.7 4.3 45.7 7.2 10.6 7.3 47.9 11.2 10.0 14.0 1.9 14.0 46.4 14.9 19.3 10.8 10.8 19.6 43.3 20.2 5.7 9.1 22.4 16.5 1.3 9.9 11.7 24.1 11.9 6.7 42.6 12.7 18.3 16.6 5.4 12.0 6.5 12.5 8.8 23.4 7.8 7.8 4.1 20.6 24.0 16.5 5.7 10.1 24.2 12.2 9.0 10.7 23.3 26.9 6.6 7.6 13.2 51.5 11.0 19.6 16.3 3.8 8.5 9.8 9.8 9.6 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 768.1;RT4: 524.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 150.8 230.8 24.0 37.5 23.9 10.7 63.0 24.6 30.9 67.9 40.8 124.9 179.4 22.9 164.9 92.2 36.6 69.5 25.3 23.5 26.1 122.0 536.3 49.8 33.3 26.4 25.7 84.4 39.9 42.0 16.7 82.5 25.9 214.6 131.2 35.0 59.3 79.1 25.7 23.6 117.4 43.8 25.5 40.1 113.6 57.0 30.0 21.8 45.5 28.1 29.8 153.1 39.9 30.6 66.5 109.6 152.5 63.3 275.1 191.4 86.7 26.3 122.3 44.2 107.3 176.1 159.1 13.1 168.8 84.4 181.6 101.4 112.4 130.7 43.0 8.8 41.7 56.7 87.3 768.1 367.3 37.0 54.7 169.5 278.0 102.7 74.2 69.8 126.1 37.2 58.1 44.5 68.9 42.8 26.3 66.2 284.5 479.7 43.9 25.2 54.8 37.8 206.3 524.0 25.9 45.2 100.5 99.7 351.7 161.2 37.9 111.0 81.1 45.2 44.1 65.3 29.6 20.8 34.5 16.9 148.2 226.7 37.0 12.4 70.1 11.0 9.1 32.3 10.6 10.6 8.2 10.9 50.9 10.1 6.7 7.8 13.8 17.2 15.5 18.8 15.1 29.9 24.0 23.9 24.6 30.9 23.5 26.1 26.4 25.7 25.9 25.5 30.0 30.6 13.9 12.8 49.5 39.2 20.2 12.4 18.8 60.5 52.3 19.5 61.8 31.5 21.8 45.8 69.1 29.5 25.0 320.2 23.7 106.8 21.5 31.1 13.8 31.0 23.4 22.0 58.4 30.3 16.6 86.5 178.8 29.6 76.0 108.8 14.0 257.5 39.7 328.2 175.3 11.8 16.2 98.4 57.0 130.2 23.8 11.2 24.5 71.7 26.6 19.7 47.8 25.4 18.6 66.4 20.0 44.8 55.5 29.3 13.7 53.2 181.2 108.5 21.9 56.6 13.1 7.8 23.6 8.0 26.2 82.4 14.9 95.6 19.8 127.1 129.3 46.7 IFFO2 ENSG00000169991 "Intermediate filament family orphan 2" Q5TF58 1 18904280-18956676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 43.0;skin 1: 169.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.0;Basal prostatic cells: 83.0;Suprabasal keratinocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "basophil: 12.6" "Lineage enriched" "Detected in single" 18 "granulocytes: 12.6" "Cell line enhanced" "Detected in many" "HDLM-2: 139.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015987, HPA064603" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Plasma membrane" "HPA015987: AB_2121678, HPA064603: AB_2685296" "unprognostic (1.43e-1)" "unprognostic (1.06e-2)" "unprognostic (2.81e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (4.34e-2)" "unprognostic (2.27e-3)" "unprognostic (3.24e-3)" "unprognostic (7.42e-2)" "unprognostic (3.24e-2)" "unprognostic (5.24e-3)" "unprognostic (2.72e-1)" "unprognostic (4.71e-1)" "unprognostic (1.36e-1)" 5.3 9.2 7.4 8.2 6.6 10.4 12.6 19.6 10.6 12.3 0.6 9.0 2.0 7.4 2.4 43.0 5.2 7.0 4.2 6.4 7.9 6.8 5.8 7.5 8.6 11.2 9.3 3.3 19.1 10.7 6.5 7.2 9.7 9.4 2.8 4.3 14.4 9.1 7.9 169.9 3.9 7.1 6.8 6.3 4.4 1.8 9.6 6.2 6.4 4.2 14.0 8.5 21.6 8.8 23.3 37.2 9.9 27.4 6.2 4.9 16.0 17.2 11.4 9.2 6.4 51.5 26.6 0.3 21.6 13.1 10.6 57.6 7.6 36.6 7.4 139.3 6.7 0.4 7.1 20.4 4.5 4.0 21.3 3.2 36.3 12.4 15.7 15.2 19.9 1.2 1.4 4.6 6.1 4.9 3.9 3.7 4.2 23.9 8.8 13.1 6.1 9.8 5.4 14.9 31.6 1.7 13.1 18.2 12.6 10.1 4.9 2.1 54.6 12.4 17.2 7.3 50.5 9.7 11.3 0.8 8.3 5.7 14.8 12.6 0.2 0.0 0.4 0.3 0.5 0.5 0.3 0.4 0.1 0.2 0.3 0.6 0.0 0.2 0.0 0.4 0.3 0.1 7.4 6.6 19.6 10.6 6.4 7.9 11.2 9.3 9.7 6.8 9.6 8.8 4.1 3.2 5.4 5.5 6.0 121.0 83.0 24.1 40.5 6.8 11.5 13.5 6.8 12.8 9.7 1.8 0.0 5.1 20.9 4.9 1.9 17.3 1.3 23.3 5.9 7.7 2.4 3.2 8.5 17.6 5.4 4.7 3.1 10.2 3.8 0.8 4.6 3.4 2.4 25.2 9.6 1.3 2.0 1.6 17.1 4.5 1.2 6.8 14.2 1.0 3.5 4.4 8.2 11.6 8.8 14.6 3.3 3.0 15.5 15.0 0.8 9.3 23.1 1.8 0.0 3.5 7.5 0.8 0.4 32.4 100.3 4.0 13.9 0.4 1.3 44.2 IFNLR1 "CRF2/12, IFNLR, IL-28R1, IL28RA" ENSG00000185436 "Interferon lambda receptor 1" Q8IU57 1 24154168-24187959 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 17.4;Proximal enterocytes: 18.2;Urothelial cells: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "memory B-cell: 4.9;naive B-cell: 5.9;plasmacytoid DC: 11.3" "Group enriched" "Detected in many" 5 "B-cells: 5.9;dendritic cells: 11.3" "Cell line enhanced" "Detected in many" "U-266/70: 51.4;U-266/84: 19.4;U-698: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017319 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA017319: AB_1851708" "prognostic favorable (5.12e-4)" "unprognostic (7.16e-2)" "unprognostic (8.61e-3)" "unprognostic (8.48e-2)" "unprognostic (8.09e-2)" "unprognostic (1.22e-2)" "unprognostic (7.28e-3)" "unprognostic (2.33e-1)" "unprognostic (5.10e-2)" "unprognostic (1.93e-1)" "unprognostic (5.51e-2)" "unprognostic (4.50e-1)" "unprognostic (3.66e-3)" "unprognostic (5.15e-2)" "unprognostic (1.69e-1)" "unprognostic (2.69e-1)" "unprognostic (1.10e-1)" 0.4 2.2 1.1 2.8 1.2 0.6 2.6 6.2 1.1 1.7 2.2 3.8 5.8 0.9 1.9 3.6 1.8 2.1 3.1 0.8 2.6 3.0 8.4 2.9 7.8 2.5 2.2 1.3 5.0 5.2 5.9 0.3 2.5 3.4 4.0 1.8 4.5 2.1 3.6 7.3 9.2 0.4 1.9 2.8 2.9 1.0 2.7 1.4 4.4 1.3 9.7 2.1 2.3 2.7 6.7 1.3 0.0 0.0 0.0 0.0 1.6 0.0 0.6 1.2 1.0 11.3 1.9 14.3 15.1 0.0 5.4 5.0 6.6 11.6 0.9 3.0 3.5 0.0 2.3 3.4 0.0 0.0 0.0 0.0 3.8 0.3 3.5 2.5 0.0 2.9 0.3 0.0 0.0 1.6 0.2 0.4 14.0 0.5 4.1 0.1 0.0 1.2 2.6 2.8 2.0 1.3 3.5 2.0 1.4 2.4 2.7 0.1 0.0 0.0 2.7 0.0 0.1 51.4 19.4 40.8 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.3 4.9 0.3 1.4 0.0 5.9 0.5 1.4 0.0 0.0 0.0 11.3 0.3 0.5 1.1 1.2 6.2 1.1 0.8 2.6 2.5 2.2 2.5 1.9 2.7 2.7 0.5 0.0 4.8 2.3 5.9 11.1 10.0 4.1 12.5 3.4 1.4 3.2 3.5 2.8 2.3 1.8 0.0 0.6 5.3 17.4 3.9 2.9 2.2 3.4 0.2 0.5 0.0 0.0 2.2 2.3 1.0 0.8 3.1 2.7 0.0 1.5 0.0 8.4 2.3 0.0 2.8 4.1 0.0 0.8 1.9 4.3 0.3 3.0 0.0 2.8 5.5 2.9 0.0 0.5 0.1 2.4 6.1 0.0 12.5 4.3 18.2 2.3 5.1 2.3 0.0 0.0 0.6 0.0 0.7 8.3 12.6 0.3 2.2 0.1 3.3 17.2 IGDCC4 "LOC57722, NOPE" ENSG00000103742 "Immunoglobulin superfamily DCC subclass member 4" Q8TDY8 15 65381484-65422947 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.3;skeletal muscle: 10.6;tongue: 14.0" "Cell type enhanced" "Detected in many" "Astrocytes: 18.6;Cone photoreceptor cells: 31.3;Fibroblasts: 14.7;Leydig cells: 34.8;Microglial cells: 14.0;Oligodendrocyte precursor cells: 17.6;Skeletal myocytes: 29.8" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.4;AF22: 9.4;CAPAN-2: 8.1;EFO-21: 4.5;HSkMC: 5.2;NTERA-2: 7.2;SuSa: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008510, HPA008576" Approved Approved Approved Nucleoplasm,Cytosol NA NA 64000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA008510: , HPA008576: AB_1079496" "unprognostic (1.16e-1)" "unprognostic (9.38e-2)" "unprognostic (1.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.58e-1)" "unprognostic (1.77e-2)" "unprognostic (2.75e-3)" "unprognostic (9.94e-2)" "unprognostic (4.18e-2)" "unprognostic (3.65e-2)" "unprognostic (3.29e-2)" "unprognostic (6.36e-2)" "unprognostic (1.83e-8)" "unprognostic (3.30e-2)" "unprognostic (4.54e-2)" "unprognostic (2.33e-1)" "unprognostic (5.32e-3)" 0.9 2.5 5.6 2.4 6.9 0.0 0.5 5.8 2.5 3.4 0.0 0.8 0.5 1.4 4.2 1.6 1.7 4.2 0.9 2.9 7.2 0.1 0.0 0.2 0.6 11.2 9.4 8.5 0.1 0.3 0.9 5.6 6.8 0.4 0.6 0.8 0.5 0.4 10.6 0.8 0.8 1.0 6.9 0.2 1.1 0.6 11.3 0.7 1.9 14.0 0.6 2.1 2.0 4.5 0.0 4.4 9.4 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.3 0.5 8.1 0.0 4.5 0.3 0.0 0.0 2.3 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.3 0.0 0.0 5.2 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.8 7.2 0.0 0.0 0.0 2.3 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.4 5.4 0.0 0.0 0.0 3.7 2.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 6.9 5.8 2.5 2.9 7.2 11.2 9.4 6.8 6.9 11.3 4.5 0.2 0.0 0.0 18.6 0.0 2.3 0.0 0.0 0.0 7.7 0.2 0.5 2.2 0.0 0.0 3.7 31.3 0.4 0.1 0.0 0.0 0.4 0.4 0.0 2.1 0.3 0.0 0.0 0.9 0.0 0.6 14.7 1.1 0.0 0.0 8.8 0.0 0.0 0.7 0.0 6.3 0.0 0.0 0.0 2.5 1.4 34.8 0.3 5.4 14.0 0.0 1.0 1.0 17.6 1.0 0.3 0.0 4.1 0.1 0.1 0.0 0.7 0.0 12.2 6.6 29.8 1.0 0.8 2.6 0.1 1.1 0.8 0.3 7.0 0.0 0.0 IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1492.5;ovary: 1323.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 1104.1;Ionocytes: 980.6;Leydig cells: 1828.2;Peritubular cells: 981.7;Sertoli cells: 1275.3;Skeletal myocytes: 2750.9;Smooth muscle cells: 1376.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 831.3;BJ hTERT+: 2192.6;T-47d: 531.7;U-138 MG: 710.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059827, HPA070407" Supported Approved "Nuclear bodies,Golgi apparatus,Vesicles" "Secreted to blood" NA NA 110000000 380000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "Nuclear bodies" "HPA059827: AB_2732640, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" 375.1 221.8 35.6 178.2 35.1 0.7 354.6 21.9 30.9 1492.5 46.9 232.3 35.0 837.7 121.3 166.4 953.0 129.3 155.0 50.4 41.8 479.1 34.2 78.2 71.3 36.3 37.9 1323.4 30.7 30.7 272.8 290.7 31.5 241.4 66.2 105.4 111.0 121.8 470.9 129.0 139.3 621.2 28.1 38.7 323.5 28.8 43.8 95.0 326.2 292.9 45.9 259.2 382.9 62.4 0.0 0.0 210.6 0.9 237.1 7.5 0.8 831.3 2192.6 108.8 10.4 0.0 1.0 0.1 3.3 2.3 0.0 0.1 26.2 0.0 5.6 0.1 8.2 218.1 4.4 0.2 103.1 0.1 1.8 33.1 0.0 14.7 0.1 24.8 0.1 0.2 0.7 0.1 0.5 70.9 0.9 1.2 2.3 0.0 3.4 0.3 0.8 1.2 70.3 249.1 14.5 8.5 14.6 100.4 0.0 12.8 531.7 0.1 80.3 710.2 42.2 109.3 41.0 0.7 0.1 0.1 1.4 0.1 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 35.1 21.9 30.9 50.4 41.8 36.3 37.9 31.5 28.1 43.8 62.4 237.3 3.2 4.4 40.1 20.6 102.5 13.5 211.0 25.0 8.7 73.9 199.9 92.0 5.7 251.6 112.2 6.2 3.9 1.7 0.0 5.9 10.3 8.4 140.2 250.7 120.8 0.0 0.0 6.0 0.0 4.5 1104.1 30.5 128.5 2.5 11.4 49.6 1.4 8.7 3.3 13.7 0.0 980.6 0.6 189.7 39.9 1828.2 18.4 101.4 29.0 0.6 674.4 0.0 5.5 0.4 2.2 0.0 981.7 5.5 17.0 0.0 1.1 120.9 18.7 1275.3 2750.9 1376.0 2.2 3.0 17.7 67.9 5.6 18.4 124.7 0.1 16.8 IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 580.8;Fibroblasts: 1360.5;Leydig cells: 1030.8;Peritubular cells: 1495.9;Sertoli cells: 1170.1;Smooth muscle cells: 420.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.6;non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 1163.6;BJ: 476.9;BJ hTERT+: 683.3;fHDF/TERT166: 1045.9;hTERT-RPE1: 468.5;U-87 MG: 631.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 120.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" NA NA 199000000 300000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" 145.8 90.2 28.1 9.2 32.6 0.4 150.5 31.8 40.8 276.6 71.6 75.5 20.8 117.2 129.5 75.8 237.4 36.8 107.0 28.4 33.1 30.6 7.7 40.4 8.7 32.7 29.2 136.8 15.9 4.8 106.3 15.7 33.2 129.3 28.0 6.6 35.9 122.2 38.5 39.2 52.5 39.0 36.7 45.2 67.6 22.2 41.7 6.8 58.4 102.2 9.2 127.1 214.1 27.2 135.3 219.6 0.2 177.3 313.9 1163.6 0.8 476.9 683.3 126.9 69.0 23.2 294.7 0.0 68.5 1045.9 96.4 453.3 3.0 42.3 26.2 1.2 2.8 4.4 37.1 33.3 111.9 0.8 1.1 325.5 2.3 57.4 11.9 468.5 30.5 7.5 0.6 9.3 53.1 0.5 6.6 1.0 6.8 4.1 150.4 2.3 4.9 5.6 10.1 3.3 1.3 8.7 152.2 0.0 10.9 4.0 6.3 0.5 132.2 87.2 41.2 95.5 18.0 5.3 10.7 0.6 631.6 6.7 49.5 0.0 0.0 31.6 0.6 6.8 3.4 0.1 1.0 5.4 2.1 0.0 0.5 6.8 0.0 0.0 20.1 0.0 0.0 1.5 28.1 32.6 31.8 40.8 28.4 33.1 32.7 29.2 33.2 36.7 41.7 27.2 83.9 6.4 4.2 2.0 3.4 113.6 41.0 580.8 23.9 2.5 5.9 29.0 21.1 10.0 37.6 20.2 0.0 3.0 3.5 0.2 11.7 87.9 9.6 4.9 99.2 71.9 0.0 3.2 3.1 8.0 4.9 1360.5 30.5 2.5 0.0 2.3 116.4 0.8 7.6 0.0 3.6 0.3 50.8 6.8 122.8 32.6 1030.8 15.2 144.1 19.7 2.5 51.1 0.0 1.5 0.9 77.1 0.0 1495.9 9.6 94.9 0.0 15.2 13.9 2.8 1170.1 102.3 420.9 3.8 6.8 8.0 87.8 3.4 14.1 0.4 0.0 34.1 IGHA1 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 7411.2;lymphoid tissue: 6397.6;salivary gland: 8904.9;stomach 1: 6664.9" "Group enriched" "Detected in many" 10 "B-cells: 17763.5;Plasma cells: 34095.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2571.8;naive B-cell: 1114.6" "Lineage enriched" "Detected in many" 284 "B-cells: 2571.8" "Cell line enhanced" "Detected in many" "HDLM-2: 17.4;RPMI-8226: 34.7;SH-SY5Y: 22.3;U-266/70: 78.2;U-266/84: 24.0" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 130000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (8.87e-5)" "unprognostic (5.36e-3)" "unprognostic (2.10e-2)" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "prognostic favorable (3.81e-5)" "unprognostic (1.17e-1)" "unprognostic (3.86e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.83e-7)" "unprognostic (8.10e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" 200.6 41.7 1.4 1121.1 1.0 918.5 953.5 0.7 6.5 214.3 4.2 5973.6 7411.2 79.9 3.5 641.9 203.5 662.9 73.8 0.6 1.3 278.5 327.7 1305.3 1420.6 3.5 1.1 40.6 115.1 3.5 38.3 6.7 1.1 202.5 1338.5 0.0 8904.9 69.0 10.8 56.7 3788.8 69.5 1.4 6397.6 6664.9 23.2 1.0 131.0 447.3 0.4 1949.0 1616.2 302.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.8 0.0 0.0 3.6 0.0 0.0 0.0 17.4 0.0 3.7 0.0 0.0 0.0 5.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.1 0.0 0.0 4.1 14.4 5.5 0.0 0.0 3.8 4.3 34.7 0.0 0.0 9.7 22.3 2.6 0.0 0.0 0.0 0.0 1.6 5.1 0.0 3.9 4.2 3.2 78.2 24.0 2.2 0.0 2.4 0.0 3.8 3.0 0.6 1.3 0.3 1.0 2571.8 0.7 1.1 1.5 1114.6 0.4 1.0 9.0 0.9 0.9 1.7 1.0 508.3 1.4 1.0 0.7 6.5 0.6 1.3 3.5 1.1 1.1 1.4 1.0 1.9 11.8 131.4 783.5 0.0 17763.5 0.0 26.0 0.0 1.2 0.0 22.4 4.6 4.7 22.8 46.4 0.0 0.0 0.7 55.5 20.8 0.0 0.0 0.0 0.1 0.1 26.5 28.4 167.0 0.0 0.0 0.5 56.5 99.4 0.1 584.8 0.0 353.8 225.1 1.6 0.0 0.0 13.6 0.0 57.8 0.0 0.0 0.0 34.6 0.0 0.0 6.7 0.0 11.3 0.0 0.0 0.0 12.8 0.0 34095.8 33.2 0.0 1.4 16.0 0.0 0.0 2.0 13.6 0.0 0.0 0.8 0.0 6.0 2514.2 0.0 27.9 1.2 IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 5017.7;salivary gland: 3728.4" "Group enriched" "Detected in many" 22 "B-cells: 3713.4;Plasma cells: 10918.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 876 "memory B-cell: 279.6;naive B-cell: 123.8" "Lineage enriched" "Detected in single" 1214 "B-cells: 279.6" "Group enriched" "Detected in some" 42 "U-266/70: 181.9;U-266/84: 63.9" "Not detected" "Not detected" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 67000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (1.98e-9)" "unprognostic (3.20e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.40e-5)" "unprognostic (4.56e-2)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (3.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.50e-6)" "unprognostic (2.12e-1)" "unprognostic (3.28e-2)" "unprognostic (9.70e-2)" "unprognostic (4.47e-1)" 24.3 3.7 0.0 14.2 0.0 12.4 329.7 0.0 0.0 47.6 0.0 5017.7 15.3 8.9 0.0 219.7 35.0 0.9 4.8 0.0 0.0 49.7 35.1 134.2 6.8 0.0 0.0 5.3 30.3 0.0 4.9 0.3 0.0 37.7 8.8 0.0 3728.4 0.1 2.1 17.8 2261.3 1.0 0.0 700.9 670.1 1.1 0.0 22.4 59.8 0.0 13.0 93.4 67.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 2.8 2.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.9 181.9 63.9 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 279.6 0.0 0.1 0.1 123.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.2 12.4 0.0 3713.4 0.0 2.4 0.0 2.8 0.0 1.4 0.3 1.2 5.7 0.6 0.0 0.0 0.1 3.2 3.7 0.0 0.0 0.0 0.0 0.0 15.6 8.5 56.2 0.0 0.0 0.0 8.0 10.7 0.0 15.2 0.0 78.9 6.0 0.3 0.0 0.0 2.9 0.0 10.8 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 10918.5 0.3 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 12.3 0.0 0.4 325.4 0.0 4.8 0.2 IGHE ENSG00000211891 "Immunoglobulin heavy constant epsilon" P01854 14 105597691-105601728 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.9;lymphoid tissue: 4.6;thyroid gland: 2.6" "Cell type enriched" "Detected in some" 50 "Plasma cells: 462.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "U-266/70: 3818.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 77000000 "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.18e-2)" "unprognostic (1.28e-2)" "unprognostic (1.54e-3)" "unprognostic (4.99e-1)" "unprognostic (4.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (2.40e-2)" "unprognostic (8.04e-2)" "unprognostic (3.88e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-2)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.63e-1)" 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 1.9 0.0 0.0 4.6 1.4 0.0 0.0 0.2 2.6 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.6 0.0 0.0 0.6 0.0 0.6 3818.2 371.6 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 462.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11451.9;urinary bladder: 3998.0" "Group enriched" "Detected in many" 16 "B-cells: 3900.5;Plasma cells: 9883.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.7" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 766.8" "Lineage enriched" "Detected in many" 123 "B-cells: 766.8" "Group enriched" "Detected in many" 9 "Karpas-707: 157.8;U-698: 392.7" "HPA001245, CAB008642" Supported "Immunoglobulin genes" NA NA 230000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" 526.0 696.8 0.7 1661.1 0.6 681.1 203.2 0.5 4.5 518.2 2.8 302.1 103.7 210.6 18.4 334.4 661.5 312.9 143.2 0.4 2.2 491.7 356.1 962.4 3281.1 4.7 3.2 407.0 38.5 7.9 35.8 2.3 2.3 209.8 85.1 0.3 391.6 250.8 13.1 28.5 1008.8 27.6 12.7 11451.9 608.9 172.8 1.2 1773.7 1277.9 0.1 5826.8 3998.0 267.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.7 0.0 0.0 2.3 0.0 0.0 0.0 8.4 0.0 5.3 0.0 0.0 0.0 22.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 157.8 0.0 0.0 1.7 2.1 2.6 0.0 0.0 2.9 15.1 3.7 0.0 0.0 18.2 17.0 3.1 0.0 0.0 0.0 0.0 0.2 10.8 0.0 3.2 3.3 4.5 4.9 0.3 392.7 0.1 3.7 0.0 0.2 0.3 0.1 0.3 0.0 0.2 766.8 0.6 0.3 0.4 134.9 0.0 0.1 6.2 0.1 0.1 0.1 0.2 96.2 0.7 0.6 0.5 4.5 0.4 2.2 4.7 3.2 2.3 12.7 1.2 1.8 2.9 73.7 378.5 0.0 3900.5 0.0 8.1 0.0 0.0 0.0 0.5 0.0 2.8 22.8 9.3 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.5 0.0 0.1 8.5 13.9 83.4 0.0 0.0 0.0 13.6 8.2 0.0 209.4 0.0 46.1 52.9 0.1 0.0 0.0 5.0 0.0 62.8 0.0 0.9 0.0 9.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 5.4 0.0 9883.3 9.1 0.0 10.9 1.5 0.1 0.0 0.0 1.5 1.9 1.0 0.0 0.0 0.0 415.6 0.0 13.6 0.1 IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 4319.4" "Group enriched" "Detected in some" 8 "B-cells: 2050.1;Plasma cells: 2918.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 447 "memory B-cell: 339.0;naive B-cell: 119.3" "Lineage enriched" "Detected in single" 661 "B-cells: 339.0" "Group enriched" "Detected in some" 4 "RH-30: 9.6;RPMI-8226: 25.1" HPA001245 Approved "Immunoglobulin genes" NA NA 250000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "prognostic favorable (3.53e-4)" "unprognostic (6.88e-3)" "unprognostic (2.40e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "prognostic favorable (3.30e-6)" "unprognostic (1.06e-1)" "unprognostic (6.67e-2)" "unprognostic (1.74e-1)" "unprognostic (7.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (4.72e-2)" "unprognostic (3.32e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-2)" 109.5 11.0 1.3 170.0 1.4 34.8 56.0 0.2 4.1 59.9 0.8 202.8 7.5 55.8 0.8 90.2 51.5 20.7 15.2 0.2 1.1 157.5 98.2 171.0 65.4 0.9 0.2 16.3 8.0 0.1 8.2 0.0 0.5 64.2 9.4 0.0 201.2 1.2 3.5 13.3 330.7 1.0 1.5 4319.4 87.2 2.3 0.3 16.7 134.4 0.0 226.0 100.4 104.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 25.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 339.0 0.5 0.0 0.3 119.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 34.5 1.3 1.4 0.2 4.1 0.2 1.1 0.9 0.2 0.5 1.5 0.3 1.8 0.2 54.5 305.3 0.0 2050.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 2.8 13.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.2 4.1 0.0 32.5 0.0 0.0 0.0 3.1 0.0 0.0 126.1 0.0 8.2 5.1 0.1 0.0 0.0 0.9 0.0 12.4 0.0 0.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2918.6 0.7 0.0 3.5 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.1 305.5 0.0 0.7 0.0 IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1289.1" "Group enriched" "Detected in many" 7 "B-cells: 2548.4;Plasma cells: 4543.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 415 "memory B-cell: 211.0;naive B-cell: 64.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.0" "Group enriched" "Detected in some" 5 "HDLM-2: 23.8;Karpas-707: 18.7;U-698: 49.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" 63.6 17.6 0.1 90.8 0.3 65.4 23.8 0.1 1.5 37.9 1.0 30.0 11.6 22.8 0.3 32.2 104.4 8.4 6.7 0.1 0.6 72.8 42.4 194.9 346.3 2.8 0.1 13.4 6.3 0.1 6.8 0.1 0.4 41.4 8.8 0.0 69.9 12.7 1.9 2.3 100.9 1.6 1.2 1289.1 65.4 31.7 0.1 27.1 87.6 0.0 929.0 87.3 29.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 6.0 3.9 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 49.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 211.0 0.0 0.0 0.0 64.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.7 0.1 0.3 0.1 1.5 0.1 0.6 2.8 0.1 0.4 1.2 0.1 1.0 1.9 57.7 363.7 0.0 2548.4 0.0 9.7 0.0 0.0 0.0 0.5 0.1 1.9 18.6 11.2 0.0 0.0 0.0 2.0 7.0 0.0 0.0 6.5 0.1 0.2 5.3 13.2 24.5 0.0 0.0 0.0 9.1 2.6 0.0 195.5 0.0 22.9 64.2 0.1 0.0 0.0 7.4 0.0 62.8 0.0 16.4 0.0 7.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.0 4543.8 13.3 0.0 0.5 2.2 0.0 0.0 0.0 0.7 4.7 0.7 0.0 0.0 0.0 467.3 0.0 13.5 0.1 IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2478.2" "Group enriched" "Detected in some" 10 "B-cells: 964.5;Plasma cells: 2099.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 122.7;naive B-cell: 73.7" "Lineage enriched" "Detected in single" 571 "B-cells: 122.7" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 339.7" HPA001245 Approved "Immunoglobulin genes" NA NA 170000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" 80.0 2.1 0.4 2478.2 0.6 42.2 5.8 0.5 1.0 33.9 0.3 40.6 85.5 10.8 0.2 401.2 28.5 101.3 19.2 0.3 0.4 44.0 43.7 49.4 136.5 0.6 0.4 3.9 4.2 0.5 1.9 0.2 1.3 31.2 44.3 0.1 16.4 4.1 0.8 4.7 186.2 1.8 1.1 831.6 57.4 2.2 0.4 49.9 108.3 0.0 872.5 588.7 29.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 43.2 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.3 0.6 339.7 0.0 0.0 3.5 3.7 0.3 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.9 0.3 1.5 0.6 0.1 57.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 122.7 0.0 0.0 0.1 73.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 19.6 0.4 0.6 0.5 1.0 0.3 0.4 0.6 0.4 1.3 1.1 0.4 0.3 1.3 6.4 118.8 0.0 964.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.0 8.6 3.7 0.0 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.0 0.4 2.5 27.8 26.7 0.0 0.0 0.0 4.3 0.0 0.0 50.4 0.0 16.4 36.7 0.0 0.0 0.0 10.5 0.0 51.9 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.3 0.0 2099.3 0.2 0.0 10.6 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 152.3 0.0 12.8 0.1 IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 354.8;lymphoid tissue: 414.0;salivary gland: 120.1;stomach 1: 305.5" "Cell type enriched" "Detected in single" 18 "Plasma cells: 1.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.9" "Group enriched" "Detected in some" 72 "memory B-cell: 276.3;naive B-cell: 180.8;plasmacytoid DC: 99.0" "Group enriched" "Detected in many" 73 "B-cells: 276.3;dendritic cells: 99.0" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.7;U-698: 1.8" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.28e-3)" "unprognostic (2.05e-2)" "unprognostic (6.81e-2)" "unprognostic (9.53e-2)" "prognostic favorable (3.55e-4)" "unprognostic (2.51e-1)" "unprognostic (2.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" 8.6 5.3 0.1 196.9 0.1 35.6 72.8 0.0 1.9 18.6 0.2 260.2 354.8 3.3 0.0 15.7 5.2 12.6 1.4 0.1 0.1 2.3 6.1 28.5 46.8 1.3 0.0 8.2 3.1 0.4 0.0 0.7 0.5 4.3 182.6 0.0 120.1 0.5 0.0 0.0 171.1 12.0 0.3 100.2 305.5 1.0 0.2 14.6 2.9 0.0 414.0 61.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.2 276.3 0.6 2.5 0.2 180.8 0.3 0.3 0.0 0.1 0.1 99.0 0.2 29.1 0.1 0.1 0.0 1.9 0.1 0.1 1.3 0.0 0.5 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 36.4;intestine: 57.9;pancreas: 61.6" "Cell type enriched" "Detected in single" 48 "Plasma cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 9.0;naive B-cell: 29.1" "Group enriched" "Detected in many" 7 "B-cells: 29.1;granulocytes: 9.0" "Cell line enhanced" "Detected in some" "Daudi: 1.5;RPMI-8226: 6.1;TIME: 8.0;U-251 MG: 2.6" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.67e-4)" "unprognostic (8.67e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.86e-5)" "unprognostic (3.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (4.22e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (9.62e-2)" "unprognostic (1.30e-1)" 16.2 3.0 0.6 0.0 0.9 0.0 0.0 0.2 2.5 1.9 0.5 0.0 0.0 0.0 0.0 36.4 0.7 9.1 0.0 0.6 0.9 0.9 10.2 17.3 0.0 1.5 0.4 11.3 61.6 0.0 0.0 0.0 1.7 7.5 57.9 0.1 0.0 4.3 0.0 2.4 0.0 0.0 1.4 0.0 0.0 0.3 0.7 0.0 2.4 0.0 0.0 5.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.2 0.0 0.9 0.0 0.7 1.1 2.6 29.1 1.5 1.2 0.0 0.4 0.7 0.0 1.2 0.0 0.6 0.9 0.2 2.5 0.6 0.9 1.5 0.4 1.7 1.4 0.7 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGHJ4 ENSG00000240041 "Immunoglobulin heavy joining 4" 14 105864215-105864260 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 416.7;lymphoid tissue: 1568.0;urinary bladder: 551.2" "Cell type enriched" "Detected in single" 148 "Plasma cells: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 187 "memory B-cell: 6029.7;naive B-cell: 2618.0" "Lineage enriched" "Detected in all" 261 "B-cells: 6029.7" "Cell line enriched" "Detected in some" 87 "U-698: 3990.3" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 7.2 0.0 2.9 0.0 240.0 0.9 10.8 0.0 3.6 377.5 0.0 0.0 0.0 200.2 7.4 4.1 12.3 0.9 2.5 0.0 39.1 0.0 0.0 8.9 30.7 0.0 0.0 13.6 0.0 2.5 22.3 7.0 416.7 0.0 0.0 0.0 0.0 20.7 0.0 0.0 2.0 45.4 7.3 3.7 3.1 32.3 3.9 0.0 1568.0 551.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 14.0 17.5 0.0 0.0 0.0 0.0 6.8 3.6 0.0 0.0 0.0 0.0 0.0 8.9 0.0 45.8 0.0 0.0 6.2 0.0 3990.3 0.0 12.2 0.0 13.9 3.6 5.4 5.0 1.3 3.0 6029.7 13.2 4.0 23.1 2618.0 1.5 6.0 20.1 3.3 6.0 0.0 6.6 1048.2 7.2 2.9 0.9 10.8 0.9 2.5 8.9 30.7 22.3 2.0 3.1 1.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ5 ENSG00000242472 "Immunoglobulin heavy joining 5" 14 105863814-105863862 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.5;breast: 73.2;intestine: 72.3;prostate: 32.7" "Cell type enriched" "Detected in single" 397 "Plasma cells: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 263 "memory B-cell: 1081.0" "Lineage enriched" "Detected in many" 263 "B-cells: 1081.0" "Group enriched" "Detected in some" 11 "HL-60: 10.5;REH: 14.0;RH-30: 18.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" 33.5 0.0 0.7 0.0 3.7 0.0 73.2 0.7 2.0 0.0 2.0 72.3 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.9 4.2 4.5 29.4 17.1 0.0 3.1 1.0 0.0 4.7 0.0 0.0 0.0 1.9 32.7 0.2 0.2 0.0 0.0 0.0 7.9 0.0 0.0 1.6 0.0 0.0 0.4 1.3 0.0 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.6 2.1 1.2 0.7 1081.0 0.4 0.6 4.1 0.0 2.6 0.9 2.3 0.7 0.6 0.0 1.1 316.0 0.7 3.7 0.7 2.0 0.9 4.2 3.1 1.0 1.9 1.6 1.3 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ6 ENSG00000211900 "Immunoglobulin heavy joining 6" 14 105863198-105863258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 142.4;intestine: 38.6;lung: 47.0;testis: 151.4;urinary bladder: 113.5" "Cell type enriched" "Detected in single" 56 "Plasma cells: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory B-cell: 316.2;naive B-cell: 112.7" "Lineage enriched" "Detected in many" 21 "B-cells: 316.2" "Cell line enhanced" "Detected in some" "U-266/84: 1.3;U-937: 1.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.1 0.9 142.4 0.0 2.6 38.6 1.0 0.0 0.0 2.1 0.5 0.9 0.3 0.0 3.0 2.4 47.0 0.4 0.4 0.1 0.0 0.0 3.7 0.0 0.0 0.3 3.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 151.4 0.3 0.0 0.7 0.0 10.7 113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.2 0.0 3.5 3.5 0.8 0.3 0.0 0.2 316.2 0.5 0.6 0.5 112.7 0.6 0.3 14.8 0.2 1.0 0.0 0.1 89.2 0.0 0.0 0.1 0.9 0.3 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHM ENSG00000211899 "Immunoglobulin heavy constant mu" P01871 14 105851705-105856218 "Disease related genes, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 1315.0;lymphoid tissue: 4112.3" "Group enriched" "Detected in many" 14 "B-cells: 3757.1;Plasma cells: 9906.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 16 "memory B-cell: 4278.4;naive B-cell: 6731.2" "Lineage enriched" "Detected in all" 19 "B-cells: 6731.2" "Group enriched" "Detected in many" 9 "Daudi: 4983.6;U-698: 4905.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" CAB008643 Uncertain "Immunoglobulin genes" NA NA 110000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008643: AB_1617732" "unprognostic (2.91e-3)" "prognostic favorable (6.49e-4)" "unprognostic (9.30e-3)" "unprognostic (9.90e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.70e-6)" "unprognostic (9.61e-3)" "unprognostic (1.01e-1)" "unprognostic (1.52e-2)" "unprognostic (3.23e-3)" "unprognostic (2.46e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (3.01e-1)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (6.28e-3)" 52.0 9.0 0.4 373.7 0.4 395.3 56.6 0.2 1.7 67.9 1.8 446.8 1204.9 11.1 10.2 66.8 38.5 141.7 50.5 0.2 0.4 48.4 84.7 180.6 3192.1 1.9 0.3 9.7 44.5 0.6 8.7 3.6 0.7 15.1 201.4 0.0 325.1 6.1 2.7 1.7 1315.0 7.9 1.0 4112.3 528.9 70.9 0.7 117.3 37.0 0.7 497.1 128.0 10.5 0.5 4.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 4983.6 2.9 0.0 0.0 0.8 0.0 0.0 0.0 21.6 0.0 3.0 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 1.7 28.7 1.2 0.0 0.0 580.2 2.2 6.9 0.0 0.0 4.0 5.8 3.0 0.5 1.2 0.0 0.2 3.8 6.5 0.0 13.8 1.2 2.5 1.5 1.5 4905.9 0.0 2.4 0.0 10.8 5.4 5.6 3.1 1.2 2.3 4278.4 5.5 6.8 5.4 6731.2 4.5 3.8 25.4 11.4 4.5 346.1 11.4 815.2 0.4 0.4 0.2 1.7 0.2 0.4 1.9 0.3 0.7 1.0 0.7 0.5 1.0 38.5 254.5 0.0 3757.1 0.0 0.2 0.0 1.2 0.0 2.2 0.8 0.3 31.5 14.2 0.0 0.0 0.0 63.8 1.8 0.0 0.0 0.0 0.0 0.1 4.2 6.7 474.1 0.0 0.0 0.0 10.8 27.5 0.0 152.6 0.0 56.7 147.9 0.1 0.0 0.0 2.2 0.0 158.1 0.0 0.0 0.0 12.4 0.0 0.0 5.2 0.0 11.3 0.0 0.0 0.0 1.2 0.0 9906.5 0.3 0.0 2.2 1.5 0.0 0.0 0.4 16.8 0.0 0.0 0.2 0.0 0.0 415.0 0.3 4.1 0.1 IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HL-60: 3.0;RPMI-8226: 2.9;TIME: 1.6" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" 22.0 3.5 0.0 0.0 0.3 0.0 22.9 0.0 0.6 54.6 0.0 223.2 0.0 8.9 4.5 162.5 24.3 7.7 2.3 0.0 0.0 16.2 14.3 58.3 0.0 0.6 0.1 8.5 3.2 1.9 1.3 0.2 0.4 10.8 0.0 0.0 234.3 0.0 0.4 1.3 103.2 2.6 0.0 486.7 84.0 0.5 0.1 0.0 33.9 0.2 0.0 156.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.6 0.5 0.8 0.0 0.0 1.1 1.2 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 1.0 0.5 0.0 0.3 0.0 1.4 0.0 3.4 0.0 0.1 0.0 0.0 0.1 73.2 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.6 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 50.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 53.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 13773.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 3.2 0.0 0.1 0.0 IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 462.7;lymphoid tissue: 1157.3" "Cell type enriched" "Detected in some" 38 "Plasma cells: 609.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 52 "memory B-cell: 285.2;naive B-cell: 347.4" "Lineage enriched" "Detected in many" 57 "B-cells: 347.4" "Cell line enriched" "Detected in some" 8 "U-266/70: 14302.7" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.63e-3)" "unprognostic (1.09e-3)" "unprognostic (1.88e-1)" "unprognostic (9.46e-2)" "unprognostic (5.78e-2)" "prognostic favorable (1.67e-5)" "unprognostic (9.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.99e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.17e-2)" "unprognostic (8.59e-2)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" 16.7 43.1 0.3 364.1 0.2 76.0 84.1 0.0 1.2 41.5 0.5 462.7 223.7 13.1 1.3 34.5 58.5 54.4 26.2 0.0 0.1 13.7 18.9 60.7 404.9 0.4 0.0 36.5 3.0 0.6 1.3 0.6 0.2 23.2 283.8 0.0 222.4 52.5 0.4 4.5 121.9 7.5 0.2 393.2 216.1 35.0 0.1 72.1 33.7 0.0 1157.3 255.5 8.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.0 0.0 2.3 0.4 2.8 0.0 0.0 3.1 0.6 0.5 0.0 0.0 1.3 1.8 0.1 0.0 0.6 0.0 0.0 0.2 0.3 0.0 1.5 0.0 1.3 14302.7 1755.5 0.5 0.0 0.4 0.0 0.3 0.6 0.1 0.3 0.0 0.2 285.2 1.6 0.7 0.2 347.4 1.5 0.6 6.1 0.2 0.3 0.5 1.1 34.0 0.3 0.2 0.0 1.2 0.0 0.1 0.4 0.0 0.2 0.2 0.1 0.6 0.0 0.0 1.3 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 609.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 335 "Plasma cells: 13473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cell line enriched" "Detected in some" 11 "Karpas-707: 148.5" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" 10.6 59.3 0.0 207.8 0.0 36.4 46.7 0.0 0.5 41.6 0.3 193.3 218.5 4.8 15.3 45.5 6.5 85.4 3.2 0.0 0.1 8.2 8.9 40.9 171.8 0.2 0.0 8.4 7.0 0.3 0.6 0.1 0.1 6.0 223.2 0.0 120.6 23.5 0.6 0.9 140.9 11.2 0.0 246.6 189.1 0.4 0.1 57.8 24.2 0.0 629.4 92.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 14.1 1.0 148.5 0.0 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 10.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.0 2.8 1.4 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 52.8 0.6 0.2 0.0 27.8 1.6 0.5 0.0 0.0 0.0 5.8 1.7 6.1 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13473.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 201 "Plasma cells: 8432.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;RPMI-8226: 1.2;SH-SY5Y: 1.2;TIME: 2.3;U-266/70: 1.1;U-266/84: 1.2" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" 5.1 1.3 0.0 0.0 0.0 0.0 7.2 0.0 0.1 6.2 0.0 67.9 0.0 2.5 1.0 4.9 3.5 0.7 5.0 0.0 0.0 3.2 4.2 15.3 0.0 0.1 0.0 3.0 5.3 0.1 0.3 0.3 0.1 1.9 45.1 0.0 67.4 0.0 0.1 0.7 34.2 0.0 0.0 125.7 25.1 0.2 0.0 0.0 10.5 0.2 0.0 5.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 0.5 1.2 0.2 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.1 1.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 1.9 41.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8432.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2878.6;stomach 1: 989.1" "Group enriched" "Detected in some" 6 "Plasma cells: 5.8;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 225 "memory B-cell: 184.5;naive B-cell: 433.4" "Lineage enriched" "Detected in many" 316 "B-cells: 433.4" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HL-60: 2.3;MOLT-4: 4.2;RPMI-8226: 2.5;U-266/70: 3.3;U-698: 7.9" "Immunoglobulin genes" NA NA 1200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" 26.1 95.3 0.1 462.7 0.1 113.1 146.7 0.0 0.7 37.5 1.0 628.2 491.2 15.0 16.8 98.6 16.0 78.0 20.2 0.0 0.1 17.5 46.6 149.6 2878.6 1.1 0.0 35.9 3.3 0.6 1.1 0.4 0.1 16.5 406.2 0.0 385.0 100.0 0.5 5.2 121.3 43.8 0.2 452.7 989.1 6.8 0.0 135.7 38.3 0.0 2219.2 295.4 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.2 0.3 1.3 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.4 3.3 0.1 7.9 0.0 0.7 0.0 0.8 0.3 0.1 0.0 0.0 0.2 184.5 0.3 0.0 0.2 433.4 0.4 0.1 0.4 0.2 0.4 1.3 0.2 33.5 0.1 0.1 0.0 0.7 0.0 0.1 1.1 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 333 "Plasma cells: 9414.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.8" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" 16.9 5.0 0.0 183.0 0.2 112.8 106.0 0.0 0.5 45.0 0.2 465.8 266.6 7.5 2.5 27.9 10.7 65.0 5.8 0.0 0.1 20.9 16.4 83.9 188.0 0.5 0.2 13.8 9.3 1.0 1.1 0.3 0.7 9.4 296.3 0.0 201.4 8.8 0.4 2.9 177.0 17.4 0.3 351.0 707.9 2.3 0.0 121.5 27.6 0.0 1426.6 249.3 12.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.6 0.4 0.0 0.1 1.2 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.4 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 66.7 0.0 0.0 0.1 67.3 0.1 0.1 3.0 0.0 0.0 0.0 0.0 10.5 0.0 0.2 0.0 0.5 0.0 0.1 0.5 0.2 0.7 0.3 0.0 0.4 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 27.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9414.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1655.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cell line enhanced" "Detected in some" "Daudi: 1.1;SH-SY5Y: 1.2" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" 9.3 25.9 0.0 175.0 0.0 38.0 66.0 0.0 0.5 34.7 0.2 220.1 193.4 6.8 12.3 38.6 6.6 43.7 8.6 0.0 0.0 6.8 10.5 29.1 123.7 0.8 0.0 7.8 2.0 0.2 0.8 0.0 0.1 4.0 167.9 0.0 119.7 3.7 0.3 0.7 116.8 11.2 0.1 219.2 206.7 1.3 0.4 44.9 17.0 0.0 613.1 109.4 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1655.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 183.3;lymphoid tissue: 380.2;salivary gland: 177.7;stomach 1: 112.8;urinary bladder: 172.6" "Cell type enriched" "Detected in some" 112 "Plasma cells: 6281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.6;memory B-cell: 24.4" "Group enriched" "Detected in many" 9 "B-cells: 24.4;T-cells: 21.6" "Cell line enhanced" "Detected in some" "BEWO: 2.2;Daudi: 1.9;HL-60: 2.1;K-562: 2.0;NB-4: 2.4;RH-30: 1.9;RPMI-8226: 4.1;SH-SY5Y: 3.7" "Immunoglobulin genes" NA NA 20000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" 12.2 36.8 0.0 24.7 0.5 1.8 23.2 0.0 1.2 13.0 0.1 183.3 4.5 5.0 0.9 11.7 16.3 29.6 1.4 0.0 0.2 9.1 10.6 40.0 0.0 1.0 0.0 5.8 19.1 0.4 1.3 0.4 0.3 9.5 14.6 0.0 177.7 23.0 0.8 4.2 107.2 0.3 0.0 380.2 112.8 0.5 0.0 0.0 14.9 0.0 10.4 172.6 9.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.8 2.4 0.7 0.0 0.0 0.0 1.9 4.1 0.0 0.0 0.0 3.7 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 1.6 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.1 0.0 21.6 24.4 0.1 0.2 0.2 0.0 0.2 0.1 2.5 0.0 0.0 0.2 0.1 1.8 0.0 0.5 0.0 1.2 0.0 0.2 1.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.1 1.1 0.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6281.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 24 "Plasma cells: 142.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cell line enhanced" "Detected in single" "Daudi: 1.2" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" 2.8 2.1 0.0 36.3 0.2 22.6 23.7 0.0 0.1 17.4 0.2 64.8 99.2 1.8 0.0 10.1 2.2 20.7 3.1 0.0 0.0 1.5 4.7 10.5 58.0 0.1 0.0 2.7 0.4 0.1 0.2 0.0 0.0 1.2 62.5 0.0 43.1 1.4 0.0 0.3 37.7 2.0 0.0 59.6 122.5 1.1 0.0 16.6 2.8 0.0 216.6 81.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 142.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3885.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.1;NB-4: 2.1;NTERA-2: 1.2;RH-30: 2.3;TIME: 1.9" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" 18.1 2.7 0.3 0.0 0.3 0.0 24.8 0.2 1.1 16.8 0.3 209.7 0.0 7.1 0.9 17.4 30.9 0.0 2.0 0.2 0.3 15.4 10.7 55.3 0.0 0.4 0.3 2.9 16.2 2.3 1.3 0.6 0.4 7.2 0.0 0.0 213.2 0.3 0.4 4.3 111.3 0.8 0.4 398.1 83.0 0.4 0.3 0.0 25.6 0.0 0.0 27.7 10.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 2.1 1.2 0.0 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.2 1.1 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 1.0 21.4 0.0 0.0 0.1 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3885.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1683.1;lymphoid tissue: 2989.8" "Cell type enriched" "Detected in some" 139 "Plasma cells: 15979.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 406 "memory B-cell: 548.5;naive B-cell: 336.7" "Lineage enriched" "Detected in many" 503 "B-cells: 548.5" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HL-60: 3.3;NB-4: 4.1;RH-30: 3.0;RPMI-8226: 9.0;SH-SY5Y: 5.8" "Immunoglobulin genes" NA NA 42000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" 66.5 189.3 0.4 912.2 0.4 185.5 343.1 0.1 2.1 80.1 1.5 1683.1 1640.8 37.0 9.8 342.6 30.1 231.2 46.4 0.1 0.3 27.3 56.4 248.7 859.5 0.8 0.1 42.6 31.0 1.5 2.7 0.9 0.4 35.3 1087.1 0.1 697.8 53.4 0.9 15.0 886.8 40.0 0.8 802.7 1058.8 35.0 0.2 197.5 52.3 0.1 2989.8 993.6 27.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 4.1 0.7 0.0 0.0 0.6 3.0 9.0 0.0 0.0 2.7 5.8 0.8 0.1 0.0 0.0 0.0 0.0 1.8 0.0 1.3 1.3 1.1 1.5 0.0 0.3 0.0 0.9 0.0 0.4 0.4 0.1 0.2 0.0 0.1 548.5 0.2 0.3 0.3 336.7 0.1 0.2 1.0 0.2 0.2 0.2 0.8 62.4 0.4 0.4 0.1 2.1 0.1 0.3 0.8 0.1 0.4 0.8 0.2 1.4 0.1 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 12.0 0.0 0.0 0.0 1.6 19.4 0.0 1.3 0.0 1.8 2.0 0.2 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15979.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.1 0.0 IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 534.0;lymphoid tissue: 1294.8;salivary gland: 459.9;stomach 1: 572.6;urinary bladder: 378.9" "Cell type enriched" "Detected in some" 184 "Plasma cells: 14426.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 409 "memory B-cell: 164.0;naive B-cell: 136.6" "Lineage enriched" "Detected in single" 446 "B-cells: 164.0" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 1.7;NB-4: 2.3;RPMI-8226: 1.7;SCLC-21H: 1.7;SH-SY5Y: 3.0;U-266/70: 1.3" "Immunoglobulin genes" NA NA 8500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" 25.3 38.5 0.1 320.5 0.2 119.7 143.9 0.0 0.4 49.3 0.5 534.0 265.5 13.3 0.0 134.6 44.8 146.5 30.3 0.4 0.2 29.2 25.1 128.2 374.9 0.6 0.2 23.0 12.3 0.7 3.3 0.7 0.2 18.6 254.9 0.0 459.9 20.4 0.9 3.5 296.1 23.6 0.1 797.4 572.6 5.9 0.1 158.2 76.6 0.1 1294.8 378.9 34.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 1.0 1.7 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 164.0 0.2 0.0 0.1 136.6 0.3 0.1 0.3 0.0 0.0 0.2 0.0 24.4 0.1 0.2 0.0 0.4 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.4 16.3 0.0 1.3 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14426.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 26 "Plasma cells: 556.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.4;HL-60: 5.3;RPMI-8226: 7.7;SH-SY5Y: 3.8;U-266/70: 8.1" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" 27.9 67.4 1.0 513.8 0.8 117.8 289.5 0.2 4.0 53.6 2.4 1066.7 882.1 16.2 14.5 127.5 18.9 141.9 32.9 0.2 0.4 15.7 41.8 210.1 795.2 1.4 0.2 110.0 29.4 1.9 1.7 0.8 0.4 23.2 775.6 0.0 619.6 39.5 0.5 3.6 343.9 37.3 0.5 476.1 1778.8 29.4 0.7 296.8 42.2 0.1 2371.2 379.8 18.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 5.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.8 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.8 2.9 7.7 0.0 0.0 1.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.7 8.1 0.0 0.2 0.0 0.8 0.0 0.2 0.6 0.1 1.1 0.0 1.9 378.9 3.6 0.9 0.3 364.1 1.4 0.6 1.0 0.2 0.1 0.2 0.5 44.6 1.0 0.8 0.2 4.0 0.2 0.4 1.4 0.2 0.4 0.5 0.7 0.7 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.0 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 556.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 211.9;stomach 1: 312.2;urinary bladder: 153.0" "Cell type enriched" "Detected in some" 28 "Plasma cells: 557.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 321 "memory B-cell: 29.4;naive B-cell: 39.0" "Lineage enriched" "Detected in single" 366 "B-cells: 39.0" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.8;SH-SY5Y: 2.3" "Immunoglobulin genes" NA NA 4000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" 9.3 2.3 0.0 23.7 0.3 11.5 43.7 0.0 0.3 46.0 0.0 101.8 102.5 2.0 0.0 10.2 3.5 10.7 0.4 0.0 0.0 2.7 9.8 10.8 4.3 0.7 0.0 4.2 2.2 1.0 0.3 0.1 0.2 2.7 66.1 0.0 58.1 5.4 0.1 1.0 48.3 4.4 0.0 83.7 312.2 0.2 0.1 0.0 3.8 0.0 211.9 153.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 557.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 516.4;lymphoid tissue: 858.8;stomach 1: 404.9" "Cell type enriched" "Detected in some" 100 "Plasma cells: 5878.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 527 "memory B-cell: 187.1;naive B-cell: 97.5" "Lineage enriched" "Detected in single" 693 "B-cells: 187.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.6" "Immunoglobulin genes" NA NA 49000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" 8.7 22.9 0.0 232.6 0.0 81.2 56.4 0.0 1.3 25.9 0.2 434.1 516.4 8.1 0.1 33.4 12.1 38.6 6.9 0.0 0.0 10.8 18.6 32.3 125.3 0.3 0.0 12.2 8.8 0.9 0.9 0.1 0.7 6.8 253.2 0.0 164.6 16.0 0.6 1.6 134.4 17.7 0.1 271.1 404.9 27.9 0.0 36.3 16.0 0.0 858.8 248.6 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.9 0.4 0.0 0.0 0.0 0.8 0.9 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 187.1 0.0 0.0 0.1 97.5 0.0 0.1 0.1 0.0 0.0 0.0 0.2 22.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 58.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.7 17.9 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5878.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 46 "Plasma cells: 717.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" 20.8 7.1 0.0 112.3 0.0 45.7 42.5 0.0 0.5 11.5 0.3 210.7 184.4 4.6 3.9 20.0 5.1 10.9 9.4 0.0 0.2 5.0 12.8 43.2 108.6 0.7 0.0 26.5 1.7 0.2 0.4 0.0 0.3 3.0 139.3 0.0 88.5 12.1 0.2 0.4 88.2 11.5 0.1 183.1 182.3 1.8 0.1 21.4 9.7 0.0 373.5 100.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 42.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.5;lymphoid tissue: 129.5;stomach 1: 43.3" "Cell type enriched" "Detected in some" 22 "Plasma cells: 176.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 99 "memory B-cell: 54.7;naive B-cell: 52.7" "Lineage enriched" "Detected in single" 101 "B-cells: 54.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" 2.9 0.8 0.0 37.1 0.0 7.9 15.5 0.0 0.1 4.7 0.0 66.5 81.5 1.0 0.3 4.1 1.9 6.7 1.4 0.0 0.0 1.8 2.8 7.7 38.5 0.1 0.0 3.2 1.3 0.1 0.1 0.0 0.0 1.1 74.0 0.0 32.2 1.9 0.0 0.3 33.9 2.3 0.0 66.9 43.3 1.6 0.0 8.2 4.6 0.0 129.5 10.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 54.7 0.0 0.0 0.0 52.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.2;lymphoid tissue: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.3;naive B-cell: 18.7" "Lineage enriched" "Detected in single" 420 "B-cells: 43.3" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: Non-specific - Mitochondria" 8.3 0.5 0.2 140.3 0.1 10.9 84.2 0.0 0.8 12.9 0.3 130.9 20.4 3.3 1.4 35.4 7.8 46.3 4.8 0.5 0.0 1.5 4.2 36.7 48.8 0.1 0.0 5.1 8.1 0.1 0.1 0.1 0.0 4.1 145.2 0.0 28.9 11.5 0.0 3.8 68.8 3.6 0.1 67.4 74.8 0.5 0.0 16.5 2.9 0.0 272.7 40.5 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 0.2 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.3;intestine: 59.5;urinary bladder: 103.9" "Cell type enriched" "Detected in some" 107 "Plasma cells: 958.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "memory B-cell: 39.7" "Lineage enriched" "Detected in single" 137 "B-cells: 39.7" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;U-2 OS: 2.3" "Immunoglobulin genes" NA NA 7200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" 3.8 0.9 0.0 0.0 0.1 11.1 3.9 0.0 0.4 15.3 0.3 59.5 0.0 1.4 1.2 27.0 3.2 47.3 0.3 0.0 0.0 1.3 3.5 13.1 41.1 0.2 0.0 5.6 0.4 0.0 0.1 0.0 0.0 3.9 32.3 0.0 16.1 5.7 0.0 1.5 10.1 1.3 0.0 31.8 6.3 0.6 0.0 0.0 2.5 0.0 39.7 103.9 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 39.7 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 958.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 461.3;lymphoid tissue: 971.3" "Cell type enriched" "Detected in some" 255 "Plasma cells: 20463.1" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 147 "memory B-cell: 134.0;naive B-cell: 107.0" "Lineage enriched" "Detected in single" 163 "B-cells: 134.0" "Cell line enhanced" "Detected in some" "Daudi: 7.6;HL-60: 3.1;K-562: 3.0;NB-4: 3.0;RPMI-8226: 5.8;SH-SY5Y: 4.8;TIME: 2.9" "Immunoglobulin genes" NA NA 39000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" 47.8 10.1 0.7 50.1 1.0 71.1 202.7 0.3 0.8 87.4 0.6 461.3 154.1 37.7 8.2 17.8 13.4 37.0 2.2 0.2 0.4 17.6 20.3 56.4 102.5 1.6 2.8 24.7 4.8 2.9 1.8 0.3 2.3 9.2 303.5 0.0 265.5 22.9 1.3 9.6 206.0 3.6 3.9 610.4 230.4 13.2 0.4 0.0 21.1 0.1 971.3 42.9 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.0 0.0 0.0 3.0 0.5 0.0 0.0 0.4 2.6 5.8 0.0 0.0 2.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.7 0.0 1.2 1.6 0.0 0.1 0.0 0.6 0.0 0.4 0.8 0.2 0.1 0.0 0.2 134.0 0.2 0.2 0.3 107.0 0.1 0.1 0.1 0.1 0.2 0.6 0.2 12.6 0.7 1.0 0.3 0.8 0.2 0.4 1.6 2.8 2.3 3.9 0.4 1.3 0.0 0.0 0.0 0.0 80.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.5 0.0 5.3 0.0 0.0 0.0 4.4 31.1 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20463.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 7.4 0.0 0.5 0.0 IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 44.8;lymphoid tissue: 87.4;salivary gland: 39.9;stomach 1: 30.7;urinary bladder: 122.6" "Cell type enriched" "Detected in some" 230 "Plasma cells: 346.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "spinal cord: 1.3" "Group enriched" "Detected in some" 206 "memory B-cell: 28.7;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 288 "B-cells: 28.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" 1.8 11.3 0.0 40.9 0.0 6.0 12.9 0.0 0.2 3.3 0.1 44.8 44.8 1.0 0.0 12.5 1.9 7.7 1.2 0.0 0.0 1.8 2.4 8.9 10.0 0.0 0.0 3.5 0.4 0.0 0.2 0.0 0.0 0.8 44.1 0.0 39.9 1.7 0.0 0.5 30.2 2.0 1.3 42.3 30.7 0.5 0.0 5.8 4.3 0.0 87.4 122.6 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 467.7;urinary bladder: 190.8" "Cell type enriched" "Detected in some" 183 "Plasma cells: 1651.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "spinal cord: 1.6" "Group enriched" "Detected in some" 48 "memory B-cell: 43.6;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.6" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.4;SH-SY5Y: 1.0" "Immunoglobulin genes" NA NA 710000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.53e-3)" "unprognostic (9.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.74e-4)" "prognostic favorable (4.64e-5)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.72e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (2.00e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (1.09e-1)" 4.3 1.7 0.0 48.0 0.0 5.4 37.6 0.0 0.3 15.4 0.0 103.8 72.1 6.5 1.5 32.2 5.3 105.2 11.7 0.0 0.7 3.9 6.3 19.1 104.0 0.2 0.2 58.0 4.7 0.2 0.5 0.0 0.1 11.4 24.9 0.0 53.2 8.4 0.1 1.3 90.4 3.1 1.6 138.6 87.8 1.3 0.2 76.0 15.7 0.0 467.7 190.8 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.1 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.7 0.2 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1651.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 197 "Plasma cells: 15696.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 602 "U-698: 5353.4" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" 7.9 3.0 0.0 0.0 0.3 0.0 9.8 0.1 1.5 12.0 0.1 83.5 0.0 5.5 0.9 7.3 22.5 0.0 2.3 0.0 0.2 7.2 7.0 33.4 0.0 0.6 0.2 22.0 1.3 0.4 0.9 0.3 0.3 3.8 2.2 0.0 82.1 0.0 0.3 2.8 54.2 0.3 0.1 283.3 48.0 0.3 0.1 0.0 19.3 0.0 0.0 278.5 4.0 1.4 3.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 2.6 3.2 0.0 0.0 1.4 0.0 4.1 0.0 0.3 0.0 0.6 3.7 0.0 0.1 8.8 0.4 1.8 0.0 0.8 5353.4 0.0 3.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.5 0.0 0.8 0.0 0.3 0.1 1.5 0.0 0.2 0.6 0.2 0.3 0.1 0.1 1.4 0.0 0.0 0.0 0.0 79.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15696.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 251.6;lymphoid tissue: 474.9;salivary gland: 247.1;urinary bladder: 541.3" "Cell type enriched" "Detected in some" 432 "Plasma cells: 48104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Daudi: 1.8;HL-60: 2.4;NB-4: 2.2;RH-30: 2.1;RPMI-8226: 1.4;U-266/70: 2.1;U-698: 2.0" "Immunoglobulin genes" NA NA 5000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (5.95e-3)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (2.38e-3)" "unprognostic (4.48e-2)" "unprognostic (2.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.23e-2)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (2.04e-2)" "unprognostic (2.77e-1)" "unprognostic (7.68e-2)" "unprognostic (8.33e-2)" 17.8 6.5 0.5 378.0 0.5 14.5 33.2 0.1 0.8 24.0 1.5 251.6 4.4 12.5 2.5 19.1 17.7 0.0 11.4 0.1 0.2 13.8 13.8 54.9 0.0 0.8 1.2 17.6 3.7 1.2 1.4 0.0 0.6 7.1 5.0 0.0 247.1 9.5 0.5 12.1 143.6 2.0 0.1 474.9 108.1 1.3 0.4 2.8 37.2 0.0 5.3 541.3 13.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 1.1 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.2 0.2 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.2 1.6 0.1 0.1 0.1 1.7 0.5 0.1 1.1 0.1 0.1 0.2 0.1 0.0 0.5 0.5 0.1 0.8 0.1 0.2 0.8 1.2 0.6 0.1 0.4 0.3 0.0 0.0 0.0 0.0 89.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 111.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48104.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.3 0.0 IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 567.7;urinary bladder: 768.4" "Cell type enriched" "Detected in some" 285 "Plasma cells: 2624.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "midbrain: 4.8" "Group enriched" "Detected in some" 23 "memory B-cell: 56.6;naive B-cell: 31.2" "Lineage enriched" "Detected in many" 30 "B-cells: 56.6" "Cell line enriched" "Detected in some" 18 "Karpas-707: 34.5" "Immunoglobulin genes" NA NA 3800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.60e-6)" "unprognostic (2.24e-1)" "unprognostic (6.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (3.16e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" 9.4 2.5 0.0 131.4 0.0 17.8 63.6 0.0 0.2 37.5 0.1 205.2 159.9 3.8 0.8 59.8 53.4 104.9 0.9 0.0 0.1 5.5 6.6 36.9 173.2 0.3 4.8 10.0 6.0 0.4 0.4 0.0 0.1 4.0 140.2 0.0 78.2 15.0 0.3 3.8 78.6 13.4 0.4 186.4 175.0 1.6 0.1 31.8 16.7 0.0 567.7 768.4 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 34.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 56.6 0.2 0.2 0.0 31.2 0.6 0.0 0.0 0.0 0.0 1.9 0.6 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 4.8 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2624.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 525.9;lymphoid tissue: 911.2;urinary bladder: 702.5" "Cell type enriched" "Detected in some" 301 "Plasma cells: 12374.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.0" "Group enriched" "Detected in some" 37 "memory B-cell: 169.0;naive B-cell: 77.2" "Lineage enriched" "Detected in many" 51 "B-cells: 169.0" "Cell line enhanced" "Detected in some" "MOLT-4: 8.1;SCLC-21H: 2.0;SH-SY5Y: 4.2" "Immunoglobulin genes" NA NA 5500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" 23.9 3.2 0.0 260.5 0.3 95.5 89.3 0.0 1.1 40.4 0.8 525.9 301.0 12.1 2.7 89.6 17.9 168.0 27.9 0.0 0.6 13.8 20.6 89.9 148.0 0.3 0.1 23.5 10.3 1.7 1.5 0.3 0.2 12.6 456.0 0.0 225.7 8.8 0.5 3.6 222.6 19.5 2.0 465.3 260.5 15.0 0.2 86.4 44.1 0.0 911.2 702.5 10.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 8.1 1.0 0.3 0.3 0.0 0.8 1.0 0.7 0.0 0.0 2.0 4.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.4 0.4 0.1 1.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.2 1.4 77.2 0.1 0.0 0.0 0.0 0.1 3.3 0.1 11.9 0.0 0.3 0.0 1.1 0.0 0.6 0.3 0.1 0.2 2.0 0.2 0.3 0.0 0.0 0.6 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12374.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.6 0.0 0.5 0.0 IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 206.7;lymphoid tissue: 385.2;stomach 1: 143.1" "Cell type enriched" "Detected in some" 98 "Plasma cells: 2432.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 25.5" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Cell line enriched" "Detected in single" 11 "MOLT-4: 8.7" "Immunoglobulin genes" NA NA 4400000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" 6.4 44.4 0.0 97.5 0.1 30.8 56.0 0.0 0.2 10.1 0.1 206.7 185.7 5.8 0.0 15.5 5.0 22.4 3.1 0.0 0.1 5.5 10.5 28.2 54.4 0.3 0.1 10.4 1.3 0.2 0.7 0.0 0.3 4.1 121.8 0.0 104.3 7.0 0.2 0.7 86.5 8.0 0.3 181.3 143.1 0.9 0.0 30.1 23.0 0.0 385.2 43.9 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.0 0.0 8.7 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.1 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.6 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2432.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 316.6;lymphoid tissue: 568.1" "Cell type enriched" "Detected in single" 36 "B-cells: 3.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 74.8;naive B-cell: 66.7" "Lineage enriched" "Detected in many" 16 "B-cells: 74.8" "Group enriched" "Detected in some" 6 "Daudi: 9.4;U-698: 4.8" HPA006014 Approved "Immunoglobulin genes" NA NA 1200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA006014: " 4.5 28.4 0.0 229.8 0.0 38.7 102.0 0.0 0.9 68.9 0.1 274.0 0.9 10.8 0.0 111.5 20.0 92.5 6.2 0.0 0.0 5.5 7.3 128.3 121.2 0.1 0.0 54.0 5.7 0.4 0.3 0.2 0.2 6.9 316.6 0.0 75.5 19.0 0.1 1.6 51.6 10.9 0.0 203.8 148.3 0.1 0.0 39.3 7.3 0.0 568.1 196.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.0 4.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 0.0 0.0 0.0 66.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 245.7;lymphoid tissue: 547.1;salivary gland: 224.5;urinary bladder: 353.3" "Cell type enriched" "Detected in some" 87 "Plasma cells: 5993.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;Daudi: 3.7;K-562: 2.4;NB-4: 1.7;TIME: 3.3" HPA006014 Approved "Immunoglobulin genes" NA NA 2700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA006014: " "unprognostic (2.03e-3)" "unprognostic (1.00e-1)" "unprognostic (3.21e-2)" "unprognostic (7.65e-3)" "unprognostic (1.80e-2)" "prognostic favorable (5.47e-4)" "unprognostic (2.40e-2)" "unprognostic (1.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.70e-1)" "unprognostic (1.17e-1)" 20.0 4.8 0.3 0.0 0.0 0.0 25.9 0.1 1.7 17.8 0.7 245.7 0.0 8.6 6.3 19.1 15.2 27.1 2.1 0.1 0.7 15.4 15.0 56.2 0.0 0.9 0.0 8.8 17.1 1.0 2.2 0.6 0.2 11.2 0.0 0.0 224.5 0.0 0.7 3.2 144.8 1.7 0.6 547.1 99.9 4.8 0.1 0.0 25.6 0.0 0.0 353.3 14.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 1.3 1.2 0.8 0.0 0.1 0.0 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.7 0.1 0.7 0.9 0.0 0.2 0.6 0.1 1.3 0.0 0.0 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 44.9 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5993.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 175 "Plasma cells: 2295.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" 13.0 2.1 0.3 0.0 0.1 0.0 7.5 0.0 0.4 4.2 0.2 441.3 0.0 1.2 0.0 17.9 4.3 1.5 2.7 0.0 0.1 3.2 6.2 13.6 0.0 0.3 0.1 0.9 11.5 0.0 0.3 0.0 0.1 1.6 0.0 0.0 56.7 8.6 0.1 2.0 40.9 11.2 0.3 159.0 19.5 0.3 0.2 0.0 6.8 0.0 0.0 3.7 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.1 19.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.1 0.3 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2295.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 35196.7;lymphoid tissue: 63075.6" "Group enriched" "Detected in many" 12 "B-cells: 72318.1;Plasma cells: 96515.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39143.0;naive B-cell: 35081.5" "Lineage enriched" "Detected in all" 23 "B-cells: 39143.0" "Group enriched" "Detected in many" 6 "Daudi: 9909.1;U-266/70: 10337.6;U-266/84: 3927.9;U-698: 12154.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB015377 Uncertain "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB015377: AB_2251264" "prognostic favorable (6.59e-4)" "unprognostic (1.04e-2)" "unprognostic (3.54e-2)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "prognostic favorable (1.18e-4)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (3.19e-2)" "unprognostic (2.81e-3)" "unprognostic (2.82e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (2.17e-9)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" 1025.4 2379.8 13.1 20500.0 13.3 6315.2 11287.7 11.3 33.6 3649.2 26.7 35196.7 24515.5 877.3 474.1 5708.4 1137.6 5995.3 810.4 11.4 16.7 1176.6 1580.5 5824.2 21356.1 25.1 18.2 2214.9 462.9 72.6 101.8 22.2 15.3 843.6 30618.3 4.0 19606.1 2123.2 32.9 250.8 17061.1 1259.7 43.5 26904.1 22740.5 1083.9 13.4 8576.0 2151.1 8.1 63075.6 24817.5 705.0 20.2 17.1 0.0 0.0 0.0 0.0 0.0 103.7 0.0 0.0 0.1 0.0 0.0 0.0 9909.1 15.3 0.0 1.0 22.2 0.0 0.0 0.0 510.2 0.0 30.9 0.0 0.0 0.0 67.8 29.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.8 0.4 0.0 0.0 18.3 83.2 28.8 0.0 0.0 16.7 56.4 1509.5 0.6 0.0 79.6 146.1 19.6 1.5 6.0 0.5 0.5 17.2 66.7 0.0 56.9 24.3 44.0 10337.6 3927.9 12154.4 0.0 28.9 0.0 47.5 55.6 31.6 24.6 11.2 21.7 39143.0 28.3 18.3 46.6 35081.5 15.2 16.8 65.2 24.1 29.1 1735.4 23.7 8567.0 13.1 13.3 11.3 33.6 11.4 16.7 25.1 18.2 15.3 43.5 13.4 20.2 58.6 336.5 1863.8 0.0 72318.1 0.0 189.2 0.0 2.2 0.0 8.8 7.0 5.7 163.0 88.5 0.0 0.0 48.0 452.1 39.8 3.9 0.0 2.8 0.7 0.3 72.8 77.8 1658.9 0.0 0.2 37.3 186.5 64.7 0.4 849.0 15.5 340.2 334.8 8.9 0.0 0.0 35.1 0.0 496.3 0.0 11.0 0.0 64.4 0.0 0.0 26.4 0.0 59.8 0.0 0.0 0.0 25.9 0.4 96515.7 193.2 0.3 45.2 12.4 0.0 0.0 3.7 38.4 0.3 0.2 5.9 0.0 49.4 6505.3 0.1 50.2 1.9 IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 3082.3;lymphoid tissue: 3301.5;salivary gland: 1202.6;stomach 1: 2816.8;urinary bladder: 1106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38345.4;naive B-cell: 32121.1;plasmacytoid DC: 14778.6" "Group enriched" "Detected in all" 390 "B-cells: 38345.4;dendritic cells: 14778.6" "Cell line enriched" "Detected in many" 4 "U-266/70: 21925.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" 70.6 227.2 1.9 3301.5 1.5 424.8 363.1 1.3 9.2 71.7 5.0 1960.8 3082.3 41.6 0.0 278.0 18.1 157.4 31.0 3.2 2.2 31.7 92.0 382.5 839.3 3.4 2.4 127.7 50.3 2.0 0.0 6.3 2.9 50.4 1743.7 0.2 1202.6 16.4 6.9 8.8 2231.5 61.2 3.4 1516.0 2816.8 31.2 2.1 115.3 6.2 0.0 2770.1 1106.5 0.0 2.9 22.9 0.0 0.0 0.0 0.0 0.0 62.7 0.0 0.0 0.0 0.0 7.4 0.0 9.9 2.5 0.0 0.0 14.6 0.0 0.0 0.0 851.1 0.0 10.1 0.0 0.0 0.0 34.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 10.3 12.1 11.8 0.0 0.0 23.1 0.0 4365.8 0.0 0.0 10.3 18.7 0.0 0.0 4.9 0.0 0.0 31.0 0.0 0.0 9.7 2.4 34.6 21925.7 5461.9 93.7 0.0 6.3 0.0 48.3 44.8 22.7 19.1 17.9 25.4 38345.4 27.2 13.8 57.2 32121.1 20.1 20.9 68.0 38.9 26.9 14778.6 29.9 3897.0 1.9 1.5 1.3 9.2 3.2 2.2 3.4 2.4 2.9 3.4 2.1 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ2 J2 ENSG00000211596 "Immunoglobulin kappa joining 2" 2 88861525-88861563 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 2670.6;lymphoid tissue: 2226.1;salivary gland: 1187.7;stomach 1: 1719.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 22200.6;naive B-cell: 20663.6" "Lineage enriched" "Detected in all" 52 "B-cells: 22200.6" "Group enriched" "Detected in many" 7 "HDLM-2: 213.9;RPMI-8226: 179.1" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" 67.9 154.0 0.6 1862.6 0.9 296.5 312.9 0.1 4.0 158.7 0.7 1762.7 2670.6 37.5 0.0 308.3 14.3 114.1 19.6 0.6 0.6 27.0 61.7 236.7 693.3 4.3 1.4 71.6 72.5 1.9 0.0 1.1 1.2 46.0 1364.3 0.0 1187.7 20.2 2.9 5.2 1974.3 28.2 1.5 1097.1 1719.7 44.8 0.9 73.5 5.1 0.0 2226.1 494.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 3.5 0.0 0.0 0.0 213.9 0.0 9.7 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 8.0 3.6 0.0 0.0 7.4 2.5 179.1 0.0 0.0 3.2 17.5 4.8 0.0 0.0 0.0 0.0 29.6 10.7 0.0 3.4 3.7 7.6 5.3 0.0 29.0 0.0 1.8 0.0 19.7 33.6 12.8 10.3 7.7 12.8 22200.6 15.0 8.1 23.3 20663.6 9.5 9.6 42.6 10.8 18.6 430.3 17.4 2451.2 0.6 0.9 0.1 4.0 0.6 0.6 4.3 1.4 1.2 1.5 0.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKJ3 ENSG00000211595 "Immunoglobulin kappa joining 3" 2 88861221-88861258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 1010.8;lymphoid tissue: 997.2;stomach 1: 710.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 12 "spinal cord: 18.3" "Group enriched" "Detected in all" 26 "memory B-cell: 8663.4;naive B-cell: 7153.9" "Lineage enriched" "Detected in all" 28 "B-cells: 8663.4" "Group enriched" "Detected in some" 6 "HDLM-2: 105.2;RPMI-8226: 89.2;U-698: 41.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 15.1 19.6 0.8 886.7 0.7 115.0 111.2 0.3 1.3 19.2 0.5 587.3 1010.8 7.6 0.0 68.8 7.9 44.8 9.3 0.9 0.6 14.3 41.1 101.9 490.2 1.2 0.5 31.1 0.0 0.0 0.0 1.9 1.5 18.2 546.6 0.6 362.3 12.6 8.7 2.5 726.3 19.9 18.3 548.6 710.1 9.7 0.9 53.9 5.1 3.9 997.2 236.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 105.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 89.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 0.0 0.0 41.2 0.0 0.0 0.0 17.0 8.6 57.9 1.9 1.1 9.2 8663.4 3.0 3.3 5.9 7153.9 5.7 5.1 61.8 7.1 15.2 309.9 7.8 660.0 0.8 0.7 0.3 1.3 0.9 0.6 1.2 0.5 1.5 18.3 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ4 ENSG00000211594 "Immunoglobulin kappa joining 4" 2 88860886-88860922 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3282.9;lymphoid tissue: 2905.5;stomach 1: 2295.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 42 "memory B-cell: 36413.7;naive B-cell: 27723.7" "Lineage enriched" "Detected in all" 48 "B-cells: 36413.7" "Cell line enhanced" "Detected in some" "BEWO: 16.9;Daudi: 23.5;HDLM-2: 58.4;RPMI-8226: 43.3;SH-SY5Y: 27.6;U-698: 25.7" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 80.0 268.7 0.6 2905.5 0.7 407.6 414.6 0.3 4.1 110.0 0.5 1844.1 3282.9 29.5 62.5 433.0 33.3 138.1 34.8 0.6 1.1 48.2 104.6 481.3 932.6 2.9 0.7 117.5 29.3 1.7 0.0 1.3 1.3 56.4 1849.6 0.3 1142.3 54.8 3.9 17.3 2184.0 78.1 2.6 1246.0 2295.9 39.7 1.8 113.5 11.4 0.0 2661.5 645.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.0 9.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 2.0 10.4 0.0 0.0 0.0 0.0 9.1 43.3 0.0 0.0 6.7 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 7.3 8.5 3.3 0.0 25.7 0.0 0.0 0.0 114.4 64.9 20.3 24.9 9.5 16.8 36413.7 15.8 15.2 32.5 27723.7 22.7 16.1 60.0 21.5 25.4 759.9 22.8 3519.3 0.6 0.7 0.3 4.1 0.6 1.1 2.9 0.7 1.3 2.6 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ5 ENSG00000211593 "Immunoglobulin kappa joining 5" 2 88860568-88860605 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 1221.3;lymphoid tissue: 1365.8;salivary gland: 643.7;stomach 1: 1066.6;urinary bladder: 436.6" "Cell type enriched" "Detected in single" 13 "B-cells: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 24 "memory B-cell: 9254.1;naive B-cell: 8737.5" "Lineage enriched" "Detected in all" 25 "B-cells: 9254.1" "Cell line enriched" "Detected in some" 24 "U-698: 3392.4" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.92e-2)" "unprognostic (2.57e-2)" "unprognostic (3.68e-2)" "unprognostic (9.30e-3)" "prognostic favorable (1.83e-4)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.49e-6)" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (2.02e-1)" 25.2 42.2 0.5 1365.8 0.7 164.5 236.5 0.6 4.5 73.7 0.3 1194.4 1221.3 13.4 5.8 130.7 8.8 78.5 26.1 0.9 0.7 18.0 30.8 157.6 529.7 1.6 0.6 63.3 29.2 6.6 0.0 4.1 1.2 22.8 1171.9 0.0 643.7 17.1 0.0 5.8 1078.7 40.6 4.9 672.7 1066.6 12.4 0.7 61.5 4.3 0.0 1213.5 436.6 0.0 0.9 17.7 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 142.3 0.0 0.0 0.0 0.0 0.0 7.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 58.5 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.3 3.5 11.4 3.2 1.9 3392.4 0.0 8.1 0.0 3.3 10.1 10.2 3.8 1.3 2.2 9254.1 18.4 3.5 7.4 8737.5 9.5 3.4 9.4 7.6 3.4 373.6 8.8 1167.3 0.5 0.7 0.6 4.5 0.9 0.7 1.6 0.6 1.2 4.9 0.7 0.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 92 "Plasma cells: 12442.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cell line enhanced" "Detected in some" "BEWO: 1.5;Daudi: 2.1;RPMI-8226: 1.9;SH-SY5Y: 1.9" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" 13.6 144.8 0.0 201.7 0.2 73.1 116.8 0.0 0.4 50.8 0.2 395.8 240.6 7.3 0.0 57.1 16.2 69.6 9.9 0.1 0.1 13.7 17.8 65.3 238.6 0.6 0.0 18.1 7.2 0.2 1.4 0.0 1.1 7.2 278.6 0.0 219.0 5.4 0.4 2.8 231.2 11.2 1.2 360.5 254.9 6.7 0.0 69.5 32.7 0.0 788.8 243.3 9.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 259.8 0.0 0.1 0.1 164.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 24.3 0.0 0.2 0.0 0.4 0.1 0.1 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 1.8 1.6 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12442.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.3 5.0 0.0 0.0 0.0 IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 559 "Plasma cells: 18463.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" 11.8 4.7 0.1 159.1 0.1 40.0 75.9 0.0 0.8 76.0 0.6 279.7 199.4 6.3 0.5 34.3 6.6 99.0 11.4 0.0 0.1 9.2 14.9 40.5 155.0 0.2 0.0 17.7 2.0 0.1 3.6 0.1 0.1 5.6 235.6 0.0 126.9 30.9 0.8 0.7 143.6 11.8 0.1 315.4 158.9 2.0 0.1 45.7 18.4 0.0 597.8 260.3 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 164.7 0.0 0.0 0.1 112.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 16.9 0.1 0.1 0.0 0.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.6 21.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18463.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0;lymphoid tissue: 347.1;salivary gland: 177.6" "Cell type enriched" "Detected in some" 126 "Plasma cells: 4951.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 683 "memory B-cell: 152.7;naive B-cell: 185.3" "Lineage enriched" "Detected in single" 748 "B-cells: 185.3" "Cell line enhanced" "Detected in single" "BEWO: 1.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 8300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" 17.2 9.2 0.0 133.5 0.0 28.5 70.0 0.0 0.4 16.8 0.1 268.0 183.3 6.2 7.7 30.4 6.9 37.5 10.7 0.1 0.1 11.8 9.7 55.2 124.7 0.7 0.3 8.8 4.9 0.2 1.0 0.0 0.1 6.4 212.3 0.0 177.6 8.8 0.6 0.9 200.2 5.1 0.2 276.9 91.9 1.0 0.0 46.9 19.4 0.0 347.1 87.7 6.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 152.7 0.1 0.1 0.1 185.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 15.8 0.0 0.0 0.0 0.4 0.1 0.1 0.7 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 12.2 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4951.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 131 "Plasma cells: 2044.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.7;SCLC-21H: 9.1;SH-SY5Y: 8.8;U-251 MG: 3.5" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" 50.5 21.9 0.1 266.2 0.5 139.5 320.5 0.6 1.0 129.8 0.4 471.5 296.2 20.7 2.8 106.2 33.4 187.2 23.2 0.2 1.6 36.7 37.9 130.4 529.5 0.4 1.0 37.0 8.3 1.9 2.7 0.4 0.7 18.7 511.9 0.2 476.4 127.7 0.7 2.5 175.9 14.5 12.0 820.8 627.3 13.5 0.2 381.9 53.9 0.2 1727.5 623.3 26.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 1.9 2.7 0.0 0.0 9.1 8.8 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.4 3.5 0.7 0.0 0.2 0.0 0.6 0.0 0.4 0.3 0.4 0.1 0.0 0.1 369.6 0.2 0.1 0.3 441.5 0.2 0.1 1.0 0.2 0.3 0.3 0.2 39.5 0.1 0.5 0.6 1.0 0.2 1.6 0.4 1.0 0.7 12.0 0.2 1.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2044.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 151 "Plasma cells: 16225.1" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cell line enriched" "Detected in some" 21 "Daudi: 194.2" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" 10.9 9.1 0.0 54.7 0.1 14.2 17.7 0.0 0.1 21.8 0.0 108.5 70.5 5.7 0.0 11.6 12.5 14.3 1.5 0.2 0.0 10.9 6.8 27.2 36.5 0.0 0.0 1.8 3.2 0.0 0.5 0.0 0.2 4.2 13.3 0.0 151.2 0.9 0.2 1.3 74.4 1.2 0.0 254.9 83.2 0.3 0.0 5.9 31.0 0.0 42.5 17.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.8 0.0 9.0 0.0 0.0 0.0 0.9 1.0 0.7 0.3 0.3 0.3 1069.8 0.5 0.4 1.1 935.1 0.3 0.6 2.5 0.4 0.6 1.3 0.8 136.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 10.7 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16225.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 4.9 0.0 0.3 0.0 IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 777.1;lymphoid tissue: 1459.2;urinary bladder: 945.2" "Cell type enriched" "Detected in some" 240 "Plasma cells: 39194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 859.0;naive B-cell: 860.5" "Lineage enriched" "Detected in many" 364 "B-cells: 860.5" "Cell line enhanced" "Detected in some" "Daudi: 4.0;HL-60: 2.4;RPMI-8226: 5.0;SCLC-21H: 2.9;SH-SY5Y: 4.5" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" 35.8 82.0 0.2 639.7 0.2 115.4 233.9 0.1 1.6 115.8 0.6 777.1 528.7 17.1 2.0 146.2 86.9 124.8 18.7 0.1 0.5 36.2 32.0 125.3 387.2 1.0 0.2 60.8 10.8 0.5 3.0 0.4 0.3 16.7 745.0 0.0 392.2 34.8 0.9 3.2 429.7 24.4 1.3 915.4 456.3 11.5 0.2 155.3 58.4 0.0 1459.2 945.2 28.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 1.6 0.5 0.0 0.0 0.3 1.0 5.0 0.0 0.0 2.9 4.5 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.7 0.4 0.6 0.1 0.4 0.0 0.6 0.0 0.7 1.2 1.3 0.5 0.2 0.4 859.0 2.3 0.3 1.0 860.5 0.2 0.3 1.4 0.4 0.6 0.7 0.6 113.5 0.2 0.2 0.1 1.6 0.1 0.5 1.0 0.2 0.3 1.3 0.2 0.5 0.0 0.0 0.6 0.0 163.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 7.0 89.7 0.0 0.0 0.0 0.7 3.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39194.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 11.8 0.0 0.2 0.0 IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 877.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" 8.2 1.7 0.1 84.1 0.1 37.0 50.3 0.0 0.4 16.5 0.1 155.5 110.5 4.0 4.1 23.5 5.0 18.1 5.3 0.0 0.0 7.7 6.3 20.0 82.3 0.1 0.1 4.0 1.8 0.0 1.1 0.0 0.0 4.3 145.9 0.0 95.0 2.2 0.2 0.6 59.1 5.1 0.2 209.5 130.3 0.7 0.0 22.7 16.4 0.0 606.3 144.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 123.6 0.0 0.0 0.1 85.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.1 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 877.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 40 "Plasma cells: 622.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" 2.1 2.5 0.0 13.5 0.0 7.1 6.7 0.0 0.1 2.0 0.0 29.7 12.0 1.3 0.0 2.9 1.4 5.4 1.5 0.0 0.0 3.3 2.1 4.8 13.7 0.0 0.0 0.5 0.9 0.0 0.1 0.0 0.0 1.4 19.3 0.0 21.2 0.7 0.0 0.1 13.9 0.6 0.0 51.3 18.6 0.3 0.0 7.0 3.3 0.0 55.0 41.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 131.0 0.0 0.4 0.1 136.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 622.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 428.1;lymphoid tissue: 671.3;stomach 1: 283.7" "Cell type enriched" "Detected in some" 116 "Plasma cells: 7178.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 705 "memory B-cell: 300.5;naive B-cell: 296.8" "Lineage enriched" "Detected in single" 709 "B-cells: 300.5" "Cell line enhanced" "Detected in some" "HL-60: 1.2;NB-4: 1.0;RPMI-8226: 2.9;TIME: 1.2" HPA048721 Approved "Immunoglobulin genes" NA NA 4500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" 12.6 12.6 0.2 184.3 0.4 53.6 202.8 0.0 1.3 15.8 0.4 428.1 267.0 8.3 0.8 52.9 78.3 30.0 13.9 0.1 0.1 15.4 17.9 40.1 201.8 0.3 0.1 20.7 2.5 0.5 1.3 0.1 0.2 12.8 348.6 0.0 221.3 13.3 0.5 1.6 182.8 13.3 0.4 313.1 283.7 35.1 0.1 85.1 34.2 0.0 671.3 187.5 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 1.0 0.3 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.2 0.0 0.2 0.4 0.1 0.2 0.0 0.1 300.5 0.1 0.0 0.3 296.8 0.0 0.1 0.3 0.2 0.2 0.1 0.3 34.5 0.2 0.4 0.0 1.3 0.1 0.1 0.3 0.1 0.2 0.4 0.1 0.3 0.0 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7178.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.6;lymphoid tissue: 47.5;salivary gland: 34.6" "Cell type enriched" "Detected in some" 178 "Plasma cells: 232.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 13.0;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 35 "B-cells: 13.0" "Cell line enhanced" "Detected in single" "RH-30: 2.2" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" 1.7 0.3 0.0 9.6 0.0 0.9 7.6 0.0 0.2 3.0 0.0 26.6 1.6 1.3 0.0 2.2 1.8 0.0 0.3 0.0 0.0 1.7 1.0 11.6 12.5 0.1 0.0 0.2 0.4 0.0 0.2 0.1 0.1 1.1 9.1 0.0 34.6 0.3 0.1 0.2 22.7 5.5 0.0 47.5 9.5 0.2 0.0 1.3 4.0 0.0 9.4 2.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.1 12.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 298 "Plasma cells: 7890.2" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Group enriched" "Detected in some" 36 "Daudi: 731.4;U-698: 516.7" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" 147.3 181.1 0.6 1609.8 0.8 466.1 990.4 0.5 4.2 369.0 2.1 2922.1 2055.2 80.0 52.5 611.3 132.1 629.8 87.5 0.4 2.0 82.3 171.8 685.1 1968.9 2.6 0.8 214.9 26.5 3.5 5.5 1.3 3.6 80.9 2261.1 0.4 1229.7 148.4 2.3 33.2 1255.9 88.7 4.2 1712.0 2259.8 27.6 1.3 770.5 209.3 0.0 6491.8 1816.1 46.9 2.5 0.3 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 731.4 0.5 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 5.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.3 6.6 2.4 0.0 0.0 1.0 2.9 10.3 0.0 0.0 11.1 17.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 2.5 0.0 0.1 516.7 0.0 1.6 0.0 0.5 0.4 0.8 0.6 0.2 0.4 470.5 0.3 0.3 0.4 733.0 0.5 0.2 2.6 0.8 0.4 0.4 0.3 47.6 0.6 0.8 0.5 4.2 0.4 2.0 2.6 0.8 3.6 4.2 1.3 2.5 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7890.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 14.0 0.0 0.0 0.0 IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1044.6;lymphoid tissue: 1735.3" "Cell type enriched" "Detected in some" 92 "Plasma cells: 1868.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 11.1" "Lineage enriched" "Detected in single" 13 "B-cells: 11.1" "Cell line enhanced" "Detected in some" "BEWO: 2.4;Daudi: 2.8;HL-60: 3.6;K-562: 2.0;NB-4: 2.7;RPMI-8226: 4.5;SCLC-21H: 2.1;SH-SY5Y: 1.7" "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" 36.2 40.2 0.2 402.4 0.2 180.2 425.2 0.1 1.1 56.6 0.9 1044.6 756.7 38.2 4.9 662.7 29.0 130.8 22.3 0.1 0.3 46.2 40.2 157.6 584.6 0.6 0.9 87.9 19.5 3.8 3.3 0.5 0.3 21.1 709.6 0.1 732.4 95.0 1.8 7.1 425.6 23.9 0.8 1207.7 530.0 161.9 0.2 167.6 84.8 0.0 1735.3 494.1 30.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 1.1 4.5 0.0 0.4 2.1 1.7 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 11.1 0.2 0.1 0.8 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.1 1.1 0.1 0.3 0.6 0.9 0.3 0.8 0.2 0.9 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1868.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 20.3 0.0 0.0 0.0 IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 365 "Plasma cells: 25365.6" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cell line enriched" "Detected in some" 388 "U-698: 8426.0" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" 15.0 9.4 0.1 160.7 0.2 75.9 237.0 0.1 1.3 19.6 0.7 631.0 394.3 5.6 0.8 37.8 11.5 35.0 17.9 0.1 0.1 15.1 29.6 67.3 176.7 1.4 0.1 15.8 7.8 0.1 2.3 0.2 0.2 7.8 324.5 0.0 220.5 23.3 0.6 2.0 260.2 19.1 0.6 670.2 323.1 21.2 0.1 40.9 18.8 0.0 600.3 207.5 21.5 1.1 5.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.1 4.6 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.1 2.7 1.9 0.0 0.4 0.0 0.9 3.8 0.0 2.6 0.0 0.0 5.6 0.0 0.0 21.7 0.1 2.6 0.3 1.7 8426.0 0.0 2.7 0.0 0.5 0.4 0.2 0.2 0.0 0.2 561.0 0.1 0.2 0.4 325.4 0.0 0.2 1.4 0.2 0.3 0.7 0.3 53.3 0.1 0.2 0.1 1.3 0.1 0.1 1.4 0.1 0.2 0.6 0.1 1.1 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 30.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25365.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.2 0.0 0.3 0.0 IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948279 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.2;lymphoid tissue: 464.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 184.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 253 "memory B-cell: 360.5;naive B-cell: 489.4" "Lineage enriched" "Detected in many" 292 "B-cells: 489.4" "Cell line enhanced" "Detected in some" "Daudi: 8.5;HDLM-2: 1.2;TIME: 2.1;U-698: 2.2" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" 11.3 1.0 0.0 73.7 0.1 29.4 49.4 0.1 1.3 12.6 0.8 252.2 97.0 3.9 0.0 9.5 6.5 14.2 3.8 0.1 0.2 3.6 8.4 41.4 139.4 0.3 0.0 9.8 2.8 0.2 0.3 0.0 0.2 3.6 110.9 0.0 106.8 10.3 0.4 3.0 67.9 2.9 0.4 170.2 126.0 1.0 0.1 38.0 7.8 0.0 464.7 35.1 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.0 2.2 0.0 0.1 0.0 0.3 0.4 0.2 0.1 0.0 0.2 360.5 0.2 0.1 0.6 489.4 0.0 0.1 1.6 0.2 0.4 0.2 0.2 42.2 0.0 0.1 0.1 1.3 0.1 0.2 0.3 0.0 0.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1373.3;lymphoid tissue: 2812.9;urinary bladder: 1822.6" "Cell type enriched" "Detected in some" 129 "Plasma cells: 27475.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "spinal cord: 19.8" "Group enriched" "Detected in many" 292 "memory B-cell: 1729.8;naive B-cell: 1401.2" "Lineage enriched" "Detected in many" 323 "B-cells: 1729.8" "Cell line enhanced" "Detected in some" "BEWO: 3.0;Daudi: 2.0;SCLC-21H: 3.7;SH-SY5Y: 4.6" HPA047702 Approved "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" 45.8 60.5 0.4 733.2 0.3 189.1 385.3 0.2 2.1 136.2 0.6 1373.3 701.6 32.1 11.5 143.5 34.0 253.5 18.9 0.2 0.6 44.4 55.2 227.4 575.7 0.6 0.7 120.8 13.7 1.9 3.2 0.9 0.9 30.1 1090.9 0.1 496.0 60.9 1.2 14.2 536.0 59.5 19.8 1100.0 788.6 22.2 0.3 261.9 88.8 0.9 2812.9 1822.6 33.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.4 1.8 1.5 0.0 0.0 3.7 4.6 0.4 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.7 0.7 0.6 1.8 0.3 0.1 0.0 1.4 0.0 1.9 1.3 1.2 2.0 0.2 0.7 1729.8 0.8 0.6 1.6 1401.2 0.8 0.8 5.3 0.9 1.1 1.2 1.3 186.7 0.4 0.3 0.2 2.1 0.2 0.6 0.6 0.7 0.9 19.8 0.3 1.0 0.0 0.0 0.5 0.0 211.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 82.6 0.0 0.0 0.0 2.5 1.9 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.7 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27475.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 62.0 0.0 0.3 0.0 IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 785.8;lymphoid tissue: 1996.3;urinary bladder: 784.8" "Cell type enriched" "Detected in some" 85 "Plasma cells: 22923.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 561 "memory B-cell: 2243.8;naive B-cell: 1651.4" "Lineage enriched" "Detected in all" 646 "B-cells: 2243.8" "Cell line enhanced" "Detected in some" "Daudi: 1.7;K-562: 1.3;NB-4: 1.9;RH-30: 1.2;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.5" HPA047702 Approved "Immunoglobulin genes" NA NA 7200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" 47.9 114.5 0.0 603.8 0.1 131.0 174.3 0.0 1.5 141.8 0.3 785.8 431.4 19.4 34.7 120.0 30.0 144.4 14.8 0.1 0.3 35.2 36.7 184.8 500.9 0.7 0.3 55.4 9.3 2.5 3.0 0.5 0.3 18.3 649.4 0.0 399.3 114.2 1.0 2.7 335.8 29.5 1.5 1020.7 629.8 64.8 0.2 250.2 77.7 0.0 1996.3 784.8 28.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.4 1.9 0.6 0.0 0.0 0.0 1.2 2.2 0.0 0.0 1.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.7 0.5 0.0 0.0 0.0 1.0 0.0 1.8 3.4 0.8 1.0 0.4 0.8 2243.8 1.0 1.1 1.8 1651.4 1.0 1.1 1.9 1.0 1.3 1.7 1.5 193.1 0.0 0.1 0.0 1.5 0.1 0.3 0.7 0.3 0.3 1.5 0.2 1.0 0.0 0.0 0.0 0.0 269.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.6 73.4 0.0 0.0 0.0 1.4 1.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22923.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.5 0.0 0.0 0.2 0.0 0.0 28.2 0.0 0.0 0.0 IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3080.6;lymphoid tissue: 5246.5" "Cell type enriched" "Detected in some" 138 "Plasma cells: 52154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 329 "memory B-cell: 1602.7;naive B-cell: 1222.4" "Lineage enriched" "Detected in many" 373 "B-cells: 1602.7" "Group enriched" "Detected in many" 215 "U-266/70: 3769.9;U-266/84: 1732.3" HPA047702 Approved "Immunoglobulin genes" NA NA 20000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" 104.8 56.4 0.9 1791.2 0.9 380.3 736.4 0.5 4.2 326.9 2.6 3080.6 1714.2 59.0 7.8 302.1 105.2 637.2 55.7 0.5 1.6 106.2 113.5 454.0 2815.6 2.1 8.4 153.5 32.8 5.8 9.6 1.8 1.4 56.1 2731.8 0.2 1270.5 224.5 3.3 13.4 1355.8 82.8 10.4 2699.1 1412.9 24.7 1.2 671.5 224.3 1.8 5246.5 1644.0 70.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.5 0.0 2.1 0.0 0.0 0.0 6.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 2.0 5.9 2.8 0.0 0.0 3.0 6.0 10.4 0.0 0.0 7.7 12.8 1.4 0.0 0.1 0.0 0.0 0.8 4.4 0.0 2.0 1.5 4.3 3769.9 1732.3 1.8 0.0 2.3 0.0 4.0 1.2 0.7 0.7 0.4 0.8 1602.7 0.8 0.6 3.5 1222.4 0.4 0.7 4.2 0.8 1.0 0.9 0.8 196.9 0.9 0.9 0.5 4.2 0.5 1.6 2.1 8.4 1.4 10.4 1.2 1.5 0.1 3.2 1.3 0.0 376.9 0.0 0.0 0.0 5.2 0.0 0.1 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 9.4 0.0 0.0 0.0 55.3 124.4 0.0 1.3 0.0 3.6 5.0 0.1 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 52154.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 26.7 0.0 0.2 0.0 IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 22.2;salivary gland: 15.9;stomach 1: 10.2" "Group enriched" "Detected in some" 37 "B-cells: 1.5;Plasma cells: 5.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 27.8;naive B-cell: 24.3" "Lineage enriched" "Detected in single" 65 "B-cells: 27.8" "Not detected" "Not detected" HPA047702 Approved "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" 0.3 0.4 0.0 15.0 0.0 4.2 3.9 0.0 0.0 2.1 0.0 18.6 15.1 0.3 0.1 1.5 0.1 1.3 0.0 0.0 0.0 0.2 0.5 1.8 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 13.6 0.0 15.9 0.1 0.0 0.0 11.2 0.7 0.0 4.9 10.2 0.0 0.0 1.4 0.1 0.0 22.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 24.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 622 "Plasma cells: 3673.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HL-60: 2.6;SiHa: 1.7" HPA047702 Approved "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" 3.1 4.4 0.1 93.5 0.4 11.1 17.1 0.1 0.5 5.9 0.3 111.6 63.0 1.0 0.0 16.4 5.2 10.1 2.3 0.1 0.2 3.6 2.0 18.0 43.6 0.4 0.2 17.9 4.0 0.3 0.1 0.0 0.2 1.7 126.7 0.0 54.1 1.1 0.1 0.6 46.7 4.3 0.3 56.3 87.4 0.2 0.1 13.0 4.5 0.0 203.0 58.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.6 0.0 0.6 0.0 0.1 0.8 0.0 0.0 0.0 0.0 181.1 0.0 0.0 0.1 155.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 27.5 0.1 0.4 0.1 0.5 0.1 0.2 0.4 0.2 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3673.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 38 "Plasma cells: 289.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cell line enriched" "Detected in some" 4 "U-266/70: 19.5" HPA047702 Approved "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" 4.0 6.3 0.0 81.2 0.0 16.0 32.4 0.0 0.6 12.2 0.1 131.8 55.9 2.7 0.0 15.3 4.2 16.2 6.4 0.0 0.1 3.0 6.4 20.6 73.5 0.2 0.1 7.1 3.3 0.0 0.3 0.1 0.1 3.7 88.1 0.0 64.0 3.3 0.1 2.6 77.7 6.0 0.3 88.4 82.5 1.2 0.0 16.2 5.2 0.0 275.4 38.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.5 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 197.3 0.0 0.1 0.1 99.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 289.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 219 "Plasma cells: 46306.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cell line enhanced" "Detected in some" "Daudi: 14.9;RPMI-8226: 10.4;SH-SY5Y: 6.9;U-266/70: 7.5" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" 55.9 296.3 0.4 1054.1 0.9 342.1 665.2 0.4 3.4 145.2 2.4 1805.7 1769.7 46.8 19.4 195.7 41.3 188.2 51.9 0.4 1.2 35.0 76.1 302.3 816.8 1.9 0.8 86.5 28.3 2.5 2.8 1.0 3.5 43.9 1318.2 0.1 701.8 89.6 1.0 8.6 1023.0 66.4 3.6 972.3 1125.7 125.7 0.7 405.1 51.0 0.1 3169.0 758.2 19.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 3.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.6 3.6 0.3 0.0 0.0 1.4 2.2 10.4 0.0 0.0 4.0 6.9 2.3 0.0 0.0 0.0 0.0 0.7 2.6 0.0 0.8 1.1 1.0 7.5 0.2 0.8 0.0 1.2 0.0 3.9 3.2 5.1 1.6 0.9 1.7 3036.3 1.9 1.1 2.8 3070.9 2.1 1.3 2.4 1.6 2.4 2.3 1.7 344.9 0.4 0.9 0.4 3.4 0.4 1.2 1.9 0.8 3.5 3.6 0.7 1.5 0.0 0.0 0.0 0.0 210.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 17.0 40.2 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46306.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 15.7 0.0 0.1 0.0 IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3264.2;lymphoid tissue: 5586.9;stomach 1: 2335.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 37.3;granulocytes: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 743 "memory B-cell: 5729.2;naive B-cell: 5821.4" "Lineage enriched" "Detected in all" 749 "B-cells: 5821.4" "Cell line enriched" "Detected in many" 5 "U-266/70: 600.3" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" 132.3 163.1 2.2 1208.8 1.9 641.9 903.4 1.7 7.0 190.8 4.4 3038.0 3264.2 63.1 2.1 535.0 113.2 640.0 104.5 1.7 2.2 148.2 114.7 470.6 2372.4 3.9 1.7 135.6 69.8 8.0 13.2 1.9 2.2 71.5 2133.6 0.7 2047.0 124.0 4.9 28.8 1389.9 78.0 2.6 3332.0 2335.3 23.7 2.3 873.2 224.5 0.0 5586.9 1948.8 79.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.0 0.0 0.0 1.0 0.0 1.9 0.2 0.0 0.0 6.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 9.1 0.0 0.0 1.1 10.2 2.0 0.0 0.0 2.3 8.9 33.4 0.0 0.0 6.3 11.1 1.4 0.0 0.0 0.0 0.0 0.3 2.5 0.0 1.3 4.3 2.6 600.3 119.9 36.5 0.0 3.5 0.0 4.2 7.7 2.0 3.7 1.7 2.9 5729.2 3.8 2.5 6.0 5821.4 0.9 2.2 7.6 2.8 4.8 5.2 3.4 897.2 2.2 1.9 1.7 7.0 1.7 2.2 3.9 1.7 2.2 2.6 2.3 3.4 0.0 6.4 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9734.6;lymphoid tissue: 19988.7;stomach 1: 10849.9" "Group enriched" "Detected in many" 40 "B-cells: 24632.2;Plasma cells: 18795.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 36 "memory B-cell: 11361.1;naive B-cell: 10650.3" "Lineage enriched" "Detected in all" 37 "B-cells: 11361.1" "Group enriched" "Detected in many" 190 "RPMI-8226: 62032.1;U-266/70: 102644.1;U-266/84: 83511.6" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.76e-5)" "unprognostic (2.29e-2)" "unprognostic (4.54e-3)" "unprognostic (1.46e-2)" "unprognostic (4.02e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.96e-2)" "unprognostic (7.52e-2)" "unprognostic (7.15e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (4.47e-9)" "unprognostic (2.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" 386.6 782.7 7.7 3871.2 6.2 2741.4 2183.6 4.6 14.9 815.5 11.4 8217.0 9734.6 194.3 207.0 1690.0 231.5 2091.8 318.3 4.6 5.7 301.6 382.3 1442.8 5543.4 11.1 5.0 540.2 112.7 16.8 31.0 7.5 6.6 264.0 5055.4 0.7 5934.2 384.9 8.6 74.2 5290.6 306.2 6.6 7090.0 10849.9 256.0 5.4 2071.4 491.7 0.6 19988.7 6482.1 176.7 10.7 120.6 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 221.4 12.0 0.0 0.0 61.9 0.0 0.0 0.0 30.5 0.0 7.7 0.0 0.0 0.0 19.2 343.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 64.7 0.0 0.0 70.1 27.7 52.3 0.0 0.0 45.3 436.2 62032.1 0.0 0.0 46.7 45.7 5.6 43.0 17.3 0.0 17.7 57.2 11.7 0.0 38.9 23.4 78.2 102644.1 83511.6 298.8 0.7 21.9 0.7 9.9 18.6 5.6 5.8 3.0 5.7 11361.1 5.8 4.5 10.9 10650.3 3.5 4.7 118.0 5.8 8.7 303.3 6.5 2385.6 7.7 6.2 4.6 14.9 4.6 5.7 11.1 5.0 6.6 6.6 5.4 10.7 4.1 32.1 121.0 0.0 24632.2 0.0 0.3 0.0 1.2 0.0 16.1 3.0 3.9 44.3 8.1 0.0 0.0 0.3 8.0 28.0 0.0 0.0 0.0 0.0 0.1 86.3 62.5 222.4 0.0 0.0 0.3 42.5 14.8 0.0 65.6 0.0 222.8 539.9 2.1 0.0 0.0 21.5 0.0 134.5 0.0 0.0 0.0 8.5 0.0 0.0 11.4 0.0 15.5 0.0 0.0 0.0 20.6 0.0 18795.5 0.0 0.0 1.4 1.5 0.0 0.0 0.2 10.2 0.0 0.0 2.8 0.0 0.1 538.6 0.0 23.7 0.0 IGLC3 IGLC ENSG00000211679 "Immunoglobulin lambda constant 3 (Kern-Oz+ marker)" P0DOY3 22 22906342-22906803 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 4115.7;lymphoid tissue: 8175.8;stomach 1: 4130.0;urinary bladder: 3726.3" "Group enriched" "Detected in many" 35 "B-cells: 12202.8;Plasma cells: 5357.3;T-cells: 3582.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 34 "memory B-cell: 7254.6;naive B-cell: 6119.2" "Lineage enriched" "Detected in all" 37 "B-cells: 7254.6" "Cell line enriched" "Detected in many" 15 "RPMI-8226: 10741.3" "CAB000050, CAB016533" Supported "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB000050: , CAB016533: AB_629719" "prognostic favorable (2.32e-4)" "unprognostic (1.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.54e-2)" "unprognostic (8.41e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.45e-2)" "unprognostic (4.59e-2)" "unprognostic (8.77e-2)" "prognostic favorable (4.58e-4)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.04e-9)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" "unprognostic (5.97e-2)" 156.2 550.9 2.6 2377.2 2.7 840.6 1388.6 1.4 9.1 220.4 7.1 4115.7 4046.3 115.2 33.2 508.5 88.0 707.7 63.7 1.3 2.8 178.6 171.7 1081.6 2745.8 7.2 1.4 247.8 47.6 7.0 19.0 3.2 2.0 134.0 2268.4 0.3 2264.0 177.1 5.8 20.7 2373.2 113.9 3.4 4261.5 4130.0 55.4 2.1 426.9 232.0 0.9 8175.8 3726.3 111.5 6.4 0.6 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 60.1 0.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 18.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 338.0 0.0 0.0 10.8 15.0 2.8 0.0 0.0 700.2 9.3 10741.3 0.0 0.0 16.6 25.1 4.4 20.8 0.0 0.0 4.9 0.8 11.1 0.0 6.3 7.2 5.0 88.0 103.4 36.1 1.2 5.3 0.5 6.4 9.1 3.9 6.0 2.0 27.3 7254.6 5.1 3.6 6.9 6119.2 2.6 3.3 60.7 4.3 4.6 195.3 4.7 1415.5 2.6 2.7 1.4 9.1 1.3 2.8 7.2 1.4 2.0 3.4 2.1 6.4 2.0 22.4 97.3 0.0 12202.8 0.0 0.7 0.0 0.0 0.0 5.4 0.5 15.3 8.6 3.7 0.0 0.0 0.2 8.8 5.0 0.0 0.0 0.0 0.0 0.1 7.4 12.2 54.8 0.0 0.0 0.0 22.1 5.6 0.1 47.9 0.0 195.9 127.7 0.2 0.0 0.0 3.5 0.0 23.1 0.0 0.0 0.0 5.6 0.0 0.0 2.0 0.0 2.1 0.0 0.0 0.0 3.1 0.0 5357.3 0.2 0.0 1.1 2.2 0.0 0.0 0.0 4.2 0.0 0.0 0.8 0.0 0.1 3582.0 0.0 6.3 0.9 IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 88.1;lymphoid tissue: 107.7;salivary gland: 70.1;stomach 1: 113.1" "Cell type enriched" "Detected in some" 10 "B-cells: 109.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 341 "memory B-cell: 128.8;naive B-cell: 133.0" "Lineage enriched" "Detected in single" 346 "B-cells: 133.0" "Cell line enriched" "Detected in some" 913 "Karpas-707: 122629.0" "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.20e-3)" "unprognostic (5.94e-2)" "unprognostic (3.91e-1)" "unprognostic (2.16e-2)" "prognostic favorable (2.03e-4)" "unprognostic (2.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (2.74e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (1.61e-6)" "unprognostic (2.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" 5.6 4.7 0.0 27.9 0.0 19.9 15.6 0.0 0.4 5.1 0.0 54.1 88.1 4.4 0.5 8.4 4.3 10.7 1.4 0.0 0.5 2.3 3.5 8.3 40.8 0.3 0.0 2.5 1.7 0.1 0.2 0.0 0.2 4.4 23.1 0.0 70.1 0.6 0.1 0.2 23.1 0.9 0.0 107.7 113.1 0.8 0.1 20.0 5.7 0.0 104.2 19.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 112.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122629.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.7 3.0 0.6 111.2 0.0 47.3 0.3 0.1 0.0 0.0 0.1 0.0 128.8 0.0 0.0 0.1 133.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 25.5 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.5 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 95.1;lymphoid tissue: 50.0;salivary gland: 32.5;stomach 1: 40.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 19.6;naive B-cell: 11.0" "Lineage enriched" "Detected in single" 31 "B-cells: 19.6" "Group enriched" "Detected in some" 6 "Daudi: 274.6;U-266/70: 310.0;U-698: 88.7" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" 2.3 0.6 0.1 43.3 0.1 9.8 1.8 0.2 0.6 0.0 0.4 17.1 95.1 0.8 0.0 2.0 0.4 5.1 0.2 0.0 0.1 0.2 0.1 2.7 50.0 0.5 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.6 13.5 0.0 32.5 0.0 0.0 0.0 43.4 2.6 0.2 31.5 40.8 1.3 0.2 5.2 0.0 0.0 34.5 4.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 274.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 3.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 310.0 37.0 88.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 19.6 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.1 0.1 0.2 0.6 0.0 0.1 0.5 0.1 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ2 ENSG00000211676 "Immunoglobulin lambda joining 2" 22 22899481-22899655 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 260.8;lymphoid tissue: 189.8;stomach 1: 212.7" "Cell type enriched" "Detected in single" 5 "Plasma cells: 1.7" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.9;endometrial cancer: 21.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "memory B-cell: 876.1;naive B-cell: 864.5" "Lineage enriched" "Detected in many" 12 "B-cells: 876.1" "Cell line enhanced" "Detected in some" "Daudi: 10.8;HMC-1: 34.1;RH-30: 89.7;U-698: 19.8" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.99e-3)" "unprognostic (5.36e-2)" "unprognostic (5.54e-2)" "unprognostic (1.13e-2)" "unprognostic (5.94e-7)" "unprognostic (1.51e-2)" "unprognostic (3.63e-2)" "unprognostic (3.66e-2)" "unprognostic (5.17e-2)" "unprognostic (2.92e-1)" 8.4 54.9 0.2 173.0 0.0 25.4 11.2 0.1 0.8 6.1 0.1 134.5 260.8 2.9 4.2 13.5 1.0 12.5 2.9 0.1 0.2 2.1 6.9 21.5 94.5 0.3 0.0 4.7 5.9 0.1 0.0 0.0 0.9 4.0 31.1 0.0 75.6 4.2 0.0 0.2 206.0 1.9 0.1 128.3 212.7 2.3 0.0 15.5 0.3 0.0 189.8 60.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.7 89.7 1.3 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 0.0 0.6 19.8 0.0 0.5 0.0 1.4 1.9 0.6 0.4 0.2 0.7 876.1 0.3 0.3 0.9 864.5 0.2 0.4 9.3 0.7 0.8 71.8 0.5 136.5 0.2 0.0 0.1 0.8 0.1 0.2 0.3 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ3 ENSG00000211678 "Immunoglobulin lambda joining 3" 22 22904850-22905025 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 552.2;lymphoid tissue: 227.6;salivary gland: 149.1;stomach 1: 462.5;urinary bladder: 147.8" "Group enriched" "Detected in some" 44 "B-cells: 4.5;Plasma cells: 4.3" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.1;endometrial cancer: 10.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Group enriched" "Detected in many" 24 "memory B-cell: 1223.9;naive B-cell: 1139.6" "Lineage enriched" "Detected in many" 25 "B-cells: 1223.9" "Group enriched" "Detected in some" 7 "Daudi: 53.6;REH: 69.6;U-266/70: 42.8;U-266/84: 22.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.19e-1)" "unprognostic (2.06e-3)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (5.00e-1)" 5.7 29.4 0.4 212.4 0.3 37.4 32.5 0.1 1.5 9.7 0.4 130.1 552.2 3.2 0.0 40.0 4.0 32.7 3.1 0.1 0.1 2.9 9.9 41.7 132.1 0.4 0.2 31.1 1.9 0.0 0.0 0.1 0.1 9.6 71.4 0.0 149.1 1.6 0.0 1.5 205.9 6.1 0.0 207.6 462.5 6.1 0.1 23.2 0.8 0.0 227.6 147.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 69.6 2.5 6.7 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 1.0 42.8 22.5 4.3 0.0 0.0 0.0 0.8 1.6 0.7 0.9 0.3 4.3 1223.9 0.8 0.5 1.3 1139.6 0.4 0.5 8.5 0.6 1.2 49.2 0.8 193.9 0.4 0.3 0.1 1.5 0.1 0.1 0.4 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 268.7;stomach 1: 122.4;urinary bladder: 86.4" "Cell type enriched" "Detected in some" 13 "Plasma cells: 59.2" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 60.9;naive B-cell: 85.8" "Lineage enriched" "Detected in single" 731 "B-cells: 85.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 980000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" 1.8 0.3 0.0 19.6 0.0 14.4 23.7 0.0 0.1 6.0 0.0 28.2 21.6 0.7 0.6 10.5 9.1 7.3 6.0 0.0 0.0 3.3 3.3 8.7 16.6 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 1.6 44.7 0.0 37.3 3.0 0.0 0.6 12.3 0.8 0.0 108.1 122.4 0.3 0.0 30.5 2.8 0.0 268.7 86.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 358 "Plasma cells: 43406.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cell line enhanced" "Detected in some" "Daudi: 3.5;RPMI-8226: 2.2;SH-SY5Y: 3.4;TIME: 2.3" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" 43.4 13.0 0.8 203.5 0.5 114.3 138.5 0.1 3.0 68.1 1.1 553.8 551.6 14.8 0.6 125.4 21.5 236.0 15.2 0.2 0.2 28.8 28.3 115.4 282.5 0.3 0.2 56.6 10.0 1.1 3.4 0.6 0.6 46.1 336.7 4.2 413.8 19.7 1.2 3.1 287.2 14.3 0.2 1029.8 1287.4 7.2 0.3 179.2 61.2 0.0 1291.5 464.8 19.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 1.0 1.1 0.0 0.0 0.2 0.8 2.2 0.0 0.0 1.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.4 0.7 0.7 1.1 1.1 0.8 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.6 666.4 0.3 0.3 0.6 576.7 0.1 0.2 1.2 0.3 0.3 0.6 0.4 53.7 0.8 0.5 0.1 3.0 0.2 0.2 0.3 0.2 0.6 0.2 0.3 1.0 0.0 0.0 0.0 0.0 121.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.2 8.0 0.0 0.0 0.0 28.6 64.2 0.0 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 43406.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 7.4 0.0 0.1 0.0 IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 589.7;lymphoid tissue: 1918.7;stomach 1: 534.3" "Cell type enriched" "Detected in some" 108 "Plasma cells: 12023.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 840 "memory B-cell: 968.8;naive B-cell: 850.4" "Lineage enriched" "Detected in many" 894 "B-cells: 968.8" "Cell line enhanced" "Detected in some" "Daudi: 21.3;RPMI-8226: 5.5;SCLC-21H: 4.1;U-698: 15.2" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" 33.9 2.0 0.1 297.2 0.0 133.4 110.2 0.0 0.8 14.3 0.0 378.7 589.7 11.8 0.0 80.1 19.5 78.7 17.5 0.0 0.0 18.7 17.1 122.2 519.5 1.3 0.2 15.3 3.6 0.0 2.6 0.0 0.4 13.8 263.1 0.0 273.0 9.4 0.7 2.4 236.5 21.4 0.0 608.7 534.3 11.6 0.1 117.8 35.1 0.0 1918.7 240.5 16.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 968.8 0.0 0.0 0.7 850.4 0.0 0.0 0.0 0.0 0.1 1.0 0.1 100.0 0.1 0.0 0.0 0.8 0.0 0.0 1.3 0.2 0.4 0.0 0.1 0.8 0.0 0.0 0.6 0.0 111.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.0 3.5 48.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12023.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.3 0.0 IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 114 "Plasma cells: 10777.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RH-30: 2.1;RPMI-8226: 4.2;SCLC-21H: 2.7;SH-SY5Y: 2.4;U-698: 7.1" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" 36.0 216.0 0.6 323.0 0.4 162.3 200.5 0.4 2.3 82.1 0.7 706.6 704.7 23.8 3.0 163.7 21.3 112.7 27.2 0.2 0.5 23.2 31.8 126.7 689.2 2.6 0.4 43.5 8.9 4.9 2.1 0.5 1.2 22.5 531.5 0.2 526.6 70.2 0.7 4.7 332.8 34.7 0.5 813.7 625.5 9.8 0.4 260.1 34.1 0.0 1804.0 367.0 10.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.7 2.1 4.2 0.0 0.0 2.7 2.4 0.5 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.6 0.0 7.1 0.0 0.9 0.0 0.7 1.2 0.5 0.7 0.1 0.5 1518.1 0.7 0.6 1.0 819.6 0.3 0.6 0.6 0.5 0.5 1.8 0.6 159.6 0.6 0.4 0.4 2.3 0.2 0.5 2.6 0.4 1.2 0.5 0.4 2.4 0.0 0.0 0.0 0.0 94.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.7 29.0 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10777.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1318.8;lymphoid tissue: 3027.3;urinary bladder: 1584.8" "Cell type enriched" "Detected in some" 312 "Plasma cells: 34336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 275.9;naive B-cell: 178.3" "Lineage enriched" "Detected in many" 10 "B-cells: 275.9" "Cell line enhanced" "Detected in many" "HEK 293: 17.9" "Immunoglobulin genes" NA NA 1700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" 43.5 318.8 1.1 484.8 1.9 274.1 627.0 4.6 7.1 73.2 2.0 1318.8 1139.1 38.0 16.9 287.4 52.8 238.0 70.2 1.4 1.6 32.7 53.3 179.1 343.1 4.0 1.4 185.0 39.0 5.8 4.1 1.5 4.2 34.4 930.0 3.1 695.2 49.5 1.9 13.1 702.1 49.8 1.9 934.5 956.7 11.7 1.5 274.0 63.0 1.7 3027.3 1584.8 17.7 2.7 1.3 0.6 1.6 3.8 3.5 1.7 5.9 1.4 3.2 3.1 2.0 2.3 1.0 8.8 1.6 0.8 1.1 3.1 1.9 3.8 2.2 1.4 17.9 3.9 4.5 2.4 0.7 3.4 1.7 5.2 1.0 2.7 0.3 0.4 3.1 0.9 3.9 0.9 3.0 1.6 2.6 3.8 3.0 2.8 4.1 2.3 2.7 8.8 3.6 1.4 8.3 4.9 2.0 1.4 1.8 0.9 2.7 0.3 4.3 4.4 9.2 1.0 1.2 2.0 2.0 2.0 0.4 2.8 0.8 0.1 0.5 0.0 0.2 0.2 26.3 275.9 0.2 0.3 0.1 178.3 0.7 0.5 0.4 0.1 0.3 0.2 0.2 26.4 1.1 1.9 4.6 7.1 1.4 1.6 4.0 1.4 4.2 1.9 1.5 2.7 0.0 0.0 0.5 0.0 109.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 4.8 35.7 0.1 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34336.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 19.3 0.0 0.0 9.4 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 179 "Plasma cells: 58316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 22672.4" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" 83.9 192.1 0.8 754.9 1.7 357.8 749.8 0.5 6.4 119.7 3.8 2622.2 2470.7 47.8 20.7 245.2 49.0 442.1 45.2 0.6 1.0 54.3 102.1 399.3 3320.0 1.6 0.6 75.3 52.1 4.5 5.6 1.2 1.0 71.0 1074.1 0.1 797.3 119.4 2.7 21.3 1262.7 62.0 1.4 1580.6 2530.1 13.9 1.3 586.1 116.5 0.5 5374.9 1165.2 35.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.8 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4453.2 0.0 0.0 8.7 8.0 1.7 0.0 0.0 4.9 3.7 22672.4 0.0 0.0 11.8 11.1 0.4 17.3 0.0 0.0 7.1 0.0 5.1 0.0 4.1 5.7 1.1 20.4 37.7 1.4 12.1 1.7 5.0 3.9 5.3 1.7 47.1 1.0 28.8 3655.3 9.6 53.9 3.3 2657.4 1.4 12.7 11.6 62.5 2.4 2.2 2.1 451.3 0.8 1.7 0.5 6.4 0.6 1.0 1.6 0.6 1.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 324.1 0.0 0.0 0.0 1.2 0.0 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 14.7 0.0 0.0 0.0 9.9 121.8 0.0 0.0 0.0 1.4 1.7 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 58316.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 36.6 0.0 0.8 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 80 "Plasma cells: 5288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Group enriched" "Detected in many" 617 "U-266/70: 64161.5;U-266/84: 56786.5" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" 18.7 7.0 1.1 325.0 0.6 96.0 155.2 0.3 2.4 26.0 1.7 1141.8 977.0 9.4 3.5 91.4 7.9 132.4 30.5 0.3 0.3 15.4 24.3 59.2 228.2 0.8 0.3 57.2 30.3 1.4 1.4 0.2 0.7 9.0 250.6 0.0 255.5 60.3 0.6 1.9 451.5 20.1 0.8 437.7 433.9 3.4 0.3 90.6 23.7 0.0 1012.4 259.0 10.3 1.0 62.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 7.6 0.0 0.0 23.1 0.0 0.0 0.0 22.3 0.0 0.5 0.0 0.0 0.0 0.7 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 11.3 1.9 14.8 0.0 0.0 97.9 0.9 10.1 0.0 0.0 1.4 2.8 0.2 0.0 9.3 0.0 0.0 29.5 0.9 0.0 9.8 0.6 38.9 64161.5 56786.5 20.4 0.0 10.1 0.0 1.2 2.4 0.6 2.1 0.7 0.9 1439.0 1.3 1.5 1.9 2097.3 0.4 1.0 14.1 1.3 1.4 0.6 0.7 174.0 1.1 0.6 0.3 2.4 0.3 0.3 0.8 0.3 0.7 0.8 0.3 1.0 0.0 3.2 0.0 0.0 65.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.5 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5288.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.2 0.0 IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 321 "Plasma cells: 56277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cell line enhanced" "Detected in some" "Daudi: 14.4;RPMI-8226: 4.5;SCLC-21H: 9.1;SH-SY5Y: 9.9" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" 44.5 70.9 0.3 485.2 0.2 332.4 317.1 0.2 2.0 192.0 0.9 1234.9 643.4 39.2 0.0 217.7 19.2 310.4 28.1 0.1 0.4 26.3 70.1 176.2 1117.0 1.0 0.3 34.1 7.6 2.7 2.0 0.7 1.5 21.9 684.4 0.2 627.3 19.6 1.2 4.1 481.7 37.2 0.4 654.2 1460.4 56.0 0.3 335.5 35.9 0.0 3325.7 679.7 30.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.2 2.4 0.8 0.0 0.0 0.5 3.0 4.5 0.0 0.0 9.1 9.9 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.6 1.7 1.8 1.2 2.8 0.0 0.3 0.0 0.7 1.1 0.5 0.3 0.4 0.4 779.5 0.6 0.2 1.2 1038.5 0.2 0.3 0.6 0.4 0.8 0.5 0.5 52.3 0.3 0.2 0.2 2.0 0.1 0.4 1.0 0.3 1.5 0.4 0.3 0.9 0.0 3.2 0.0 0.0 111.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 10.7 174.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56277.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 11.7 0.0 0.2 0.0 IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 317.0;lymphoid tissue: 707.7;stomach 1: 288.7" "Cell type enriched" "Detected in some" 52 "Plasma cells: 1090.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.3;medulla oblongata: 1.8" "Group enriched" "Detected in some" 786 "memory B-cell: 548.7;naive B-cell: 315.0" "Lineage enriched" "Detected in single" 998 "B-cells: 548.7" "Cell line enhanced" "Detected in some" "Daudi: 4.9;HL-60: 1.0;RH-30: 1.6" HPA003285 Approved "Immunoglobulin genes" NA NA 2000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "unprognostic (6.00e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.27e-4)" "unprognostic (7.40e-3)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (9.55e-2)" "unprognostic (2.79e-1)" "unprognostic (3.55e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (9.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" 33.3 112.9 0.5 144.0 0.4 65.5 111.1 0.1 3.3 41.3 0.6 308.0 176.3 7.6 4.5 56.3 7.9 43.5 20.5 0.1 0.2 12.2 20.8 48.0 230.5 1.8 0.2 14.6 10.8 0.9 0.8 0.4 0.6 11.0 317.0 0.0 139.7 10.8 0.2 8.1 94.9 5.8 0.1 217.1 288.7 97.4 0.2 25.9 8.6 0.0 707.7 140.2 7.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.2 0.0 0.2 548.7 0.1 0.2 0.2 315.0 0.0 0.2 0.3 0.1 0.1 0.3 0.1 43.2 0.5 0.4 0.1 3.3 0.1 0.2 1.8 0.2 0.6 0.1 0.2 0.2 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 7.1 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1090.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.2 0.0 IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1026.7;lymphoid tissue: 1979.7;stomach 1: 1240.2" "Cell type enriched" "Detected in some" 61 "Plasma cells: 3121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 355 "memory B-cell: 618.3;naive B-cell: 503.7" "Lineage enriched" "Detected in many" 391 "B-cells: 618.3" "Cell line enhanced" "Detected in some" "RPMI-8226: 6.2;SCLC-21H: 9.4;SH-SY5Y: 10.7;U-251 MG: 4.2" "Immunoglobulin genes" NA NA 1200000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" 49.1 20.1 0.1 402.2 0.3 185.1 313.5 0.1 2.4 69.2 0.3 1026.7 713.6 19.0 263.4 154.0 65.8 182.4 36.9 0.1 0.3 26.0 57.5 192.2 464.9 1.5 0.4 44.9 11.5 1.3 2.7 0.4 0.4 17.2 912.2 0.0 304.9 62.4 0.9 4.8 385.2 34.9 0.6 714.2 1240.2 6.0 0.4 435.0 55.4 0.0 1979.7 642.5 13.6 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 2.7 0.3 0.0 0.0 0.1 0.9 6.2 0.0 0.0 9.4 10.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.4 0.0 4.2 0.8 0.5 0.7 0.0 0.5 0.0 0.4 0.4 1.0 0.5 0.3 0.7 618.3 0.2 0.3 0.5 503.7 0.4 0.3 1.5 0.3 0.4 0.6 0.4 36.2 0.1 0.3 0.1 2.4 0.1 0.3 1.5 0.4 0.4 0.6 0.4 1.1 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.4 15.8 0.0 1.3 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1812.1;urinary bladder: 773.9" "Cell type enriched" "Detected in some" 59 "Plasma cells: 5013.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 339 "memory B-cell: 432.0;naive B-cell: 224.7" "Lineage enriched" "Detected in single" 445 "B-cells: 432.0" "Cell line enriched" "Detected in some" 103 "REH: 282.7" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-3)" "unprognostic (6.04e-3)" "unprognostic (4.21e-2)" "unprognostic (2.59e-3)" "unprognostic (4.06e-3)" "prognostic favorable (3.26e-7)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (3.86e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (9.54e-8)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (7.52e-2)" 17.6 63.4 0.3 321.9 0.2 248.2 120.7 0.1 1.6 110.0 1.6 357.4 350.4 12.9 0.5 63.1 10.2 120.4 10.8 0.1 0.2 21.5 36.4 108.6 272.7 1.0 0.1 35.6 5.7 0.7 1.4 0.4 0.4 16.8 230.8 0.0 260.8 20.2 0.5 2.3 150.7 9.0 0.3 421.0 504.5 14.4 0.3 171.6 19.9 0.0 1812.1 773.9 17.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 282.7 1.8 2.0 0.0 0.0 1.6 1.8 0.1 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 0.5 0.5 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.1 432.0 0.1 0.1 0.3 224.7 0.1 0.1 0.9 0.1 0.1 0.2 0.1 36.6 0.3 0.2 0.1 1.6 0.1 0.2 1.0 0.1 0.4 0.3 0.3 1.3 0.0 0.0 0.0 0.0 84.4 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 3.3 2.5 0.1 0.0 0.0 0.0 0.0 1.3 0.0 4.7 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5013.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.0 1.8 0.0 0.2 0.0 IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2440.7;stomach 1: 1015.7" "Cell type enriched" "Detected in some" 41 "Plasma cells: 17441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 545.0;naive B-cell: 794.2" "Lineage enriched" "Detected in many" 53 "B-cells: 794.2" "Cell line enhanced" "Detected in some" "HL-60: 2.6;RPMI-8226: 2.7;SCLC-21H: 4.6;SH-SY5Y: 5.1" HPA003285 Approved "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" 56.8 163.2 0.2 293.2 0.2 243.2 430.9 0.1 1.7 151.9 1.3 847.4 338.9 20.8 2.1 161.5 49.8 177.1 29.8 0.2 0.3 17.1 45.7 870.5 1024.7 1.8 0.2 21.8 14.5 1.7 1.7 0.5 0.6 18.9 467.5 0.0 532.3 116.5 0.7 2.4 228.9 34.1 0.4 543.5 1015.7 59.8 0.5 155.9 23.1 0.0 2440.7 779.6 20.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.7 0.4 1.7 0.0 0.0 1.6 1.5 2.7 0.0 0.0 4.6 5.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 0.1 0.8 1.8 0.2 0.7 0.0 1.3 0.0 0.8 0.4 0.3 0.7 0.1 0.2 545.0 0.4 0.1 0.5 794.2 0.2 0.1 14.9 0.3 0.6 0.3 0.3 76.5 0.2 0.2 0.1 1.7 0.2 0.3 1.8 0.2 0.6 0.4 0.5 0.6 0.0 0.0 0.0 0.0 84.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 1.9 40.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17441.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 417.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 135 "Plasma cells: 1406.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" 8.8 1.8 0.1 16.4 0.0 29.4 29.7 0.0 0.5 23.7 0.1 56.7 19.3 2.2 0.0 10.3 5.1 10.5 3.1 0.0 0.0 3.7 3.7 29.3 64.3 0.4 0.0 2.9 0.3 0.2 0.4 0.0 0.1 2.4 26.9 0.0 40.6 0.8 0.0 0.5 24.4 0.6 0.0 103.9 59.8 24.2 0.0 47.6 2.8 0.0 401.6 27.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.1 194.0 0.2 0.0 0.3 367.8 0.0 0.0 0.2 0.0 0.1 0.1 0.1 11.8 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1406.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV3-9 ENSG00000211670 "Immunoglobulin lambda variable 3-9" A0A075B6K5 22 22819010-22819756 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 313.9;stomach 1: 117.3" "Cell type enriched" "Detected in some" 9 "Plasma cells: 13.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 51 "memory B-cell: 64.7;naive B-cell: 168.7" "Lineage enriched" "Detected in many" 74 "B-cells: 168.7" "Cell line enriched" "Detected in some" 5 "U-266/70: 41.3" HPA003285 Approved "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (2.59e-4)" "unprognostic (6.52e-3)" "unprognostic (1.95e-1)" "unprognostic (5.40e-2)" "prognostic favorable (9.80e-5)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.47e-2)" "unprognostic (4.58e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-1)" 1.8 23.5 0.1 84.6 0.0 27.8 14.9 0.0 0.1 7.3 0.1 87.1 58.7 2.0 0.0 20.8 1.8 18.6 7.6 0.0 0.0 3.2 6.2 17.1 139.8 0.7 0.0 3.9 2.4 0.2 0.1 0.0 0.1 1.4 64.0 0.0 46.2 3.1 0.1 1.5 60.3 5.2 0.0 64.6 117.3 1.6 0.1 35.0 3.8 0.0 313.9 72.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 2.1 0.1 0.3 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 0.3 0.0 41.3 5.8 0.7 0.0 3.9 0.0 0.0 0.1 0.0 1.2 0.0 2.2 64.7 1.3 1.4 0.0 168.7 0.4 1.8 0.1 0.5 0.1 0.0 0.1 6.5 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 140 "Plasma cells: 4593.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 1.0;REH: 1.3;RPMI-8226: 5.4;SH-SY5Y: 1.3" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" 15.6 9.7 0.0 172.4 0.1 43.2 64.1 0.1 0.2 27.9 0.1 325.8 430.3 5.7 0.2 52.2 5.5 44.1 15.1 0.0 0.0 6.2 14.5 72.1 450.4 1.1 0.0 10.6 8.5 0.3 1.1 0.1 0.2 6.3 209.5 0.0 116.6 6.3 0.2 0.7 219.6 3.4 0.0 305.9 285.6 1.4 0.2 82.1 9.8 0.1 461.2 204.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 1.3 0.0 5.4 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.6 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 331.7 0.2 0.1 0.2 224.0 0.0 0.1 0.9 0.1 0.1 0.1 0.2 32.3 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 11.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4593.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IGSF22 "FLJ37794, IGFN2" ENSG00000179057 "Immunoglobulin superfamily member 22" Q8N9C0 11 18704312-18726230 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Distal tubular cells: 21.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026459, HPA037851" Uncertain Approved Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB026459: , HPA037851: " "unprognostic (4.05e-2)" "unprognostic (3.65e-2)" "unprognostic (2.34e-2)" "unprognostic (1.84e-1)" "unprognostic (1.23e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (8.38e-2)" "unprognostic (8.70e-2)" "unprognostic (4.24e-2)" "unprognostic (1.99e-4)" "unprognostic (9.35e-2)" "unprognostic (3.72e-4)" "unprognostic (2.87e-1)" "unprognostic (2.18e-1)" "unprognostic (3.43e-1)" "unprognostic (7.94e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.3 0.2 0.3 0.1 0.1 0.1 0.0 0.3 0.2 0.6 0.0 0.5 0.3 2.9 2.4 4.7 1.4 0.6 1.3 7.5 5.3 1.7 0.0 3.1 23.9 0.0 0.0 1.0 1.5 21.5 3.3 1.4 5.3 1.2 0.9 3.6 0.0 3.2 4.3 0.0 0.7 2.0 5.8 2.5 0.7 0.4 0.4 1.5 1.7 1.7 5.8 8.2 0.3 1.0 4.6 1.5 0.6 0.0 0.0 0.7 0.5 2.1 1.5 0.3 9.5 2.6 0.7 0.3 4.0 0.3 2.2 6.1 0.9 0.0 0.5 1.0 0.0 0.4 0.7 1.7 0.0 2.9 3.1 2.8 8.4 IGSF5 JAM4 ENSG00000183067 "Immunoglobulin superfamily member 5" Q9NSI5 21 39745407-39802096 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 8 "Syncytiotrophoblasts: 114.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 5.8" HPA057282 Uncertain Approved "Focal adhesion sites" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Focal adhesion sites" "HPA057282: AB_2683395" "unprognostic (1.06e-1)" "unprognostic (2.53e-1)" "unprognostic (7.06e-2)" "unprognostic (9.73e-5)" "unprognostic (1.56e-2)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.18e-2)" "unprognostic (2.09e-1)" "unprognostic (8.35e-2)" "unprognostic (9.61e-2)" "unprognostic (4.01e-1)" "unprognostic (4.18e-1)" "unprognostic (3.75e-2)" "unprognostic (6.89e-2)" "unprognostic (1.07e-2)" 0.3 1.2 2.0 0.2 2.8 0.4 0.9 0.6 1.9 0.7 2.4 0.4 0.3 0.7 1.9 0.2 0.7 0.4 3.3 1.5 2.6 0.4 0.4 0.3 0.4 1.5 1.6 1.0 1.5 0.2 0.6 2.5 1.3 1.4 0.7 1.2 0.5 0.4 0.2 0.5 0.3 0.4 0.7 0.4 0.5 1.1 3.6 0.6 0.6 0.1 0.4 0.4 0.1 1.4 0.7 0.4 2.4 0.6 2.3 1.8 0.6 0.4 0.6 0.6 1.0 0.4 0.7 0.8 0.6 0.9 0.9 0.6 0.8 1.6 1.3 1.3 1.1 0.7 1.9 0.3 1.4 1.0 0.3 1.7 2.9 1.5 1.7 1.2 0.3 0.3 1.4 0.5 0.9 0.9 0.2 0.3 1.3 0.6 0.4 0.4 1.1 0.4 1.0 1.0 1.1 0.3 0.6 1.6 1.0 1.0 5.8 0.6 0.2 1.0 1.2 0.5 1.0 0.5 0.4 0.5 0.6 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.0 2.8 0.6 1.9 1.5 2.6 1.5 1.6 1.3 0.7 3.6 1.4 0.0 0.0 0.0 8.5 0.0 0.0 0.2 0.0 0.0 1.2 1.0 0.8 9.7 0.0 0.1 1.8 0.0 1.6 0.0 0.6 5.9 0.6 12.8 0.0 0.4 0.2 0.0 0.0 2.9 0.2 1.7 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 4.1 0.4 0.0 0.0 0.0 4.8 0.3 0.1 0.0 0.0 0.0 1.0 0.0 5.0 1.0 0.2 0.2 0.4 0.0 1.4 0.0 6.8 0.1 0.2 0.0 0.0 0.2 0.5 0.2 0.0 0.0 114.1 0.1 1.1 0.4 2.0 IGSF6 DORA ENSG00000140749 "Immunoglobulin superfamily member 6" O95976 16 21639550-21652608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.8" "Group enriched" "Detected in many" 13 "Hofbauer cells: 216.2;Kupffer cells: 246.9;Langerhans cells: 132.6;Macrophages: 327.1;monocytes: 179.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 1213.7" "Lineage enhanced" "Detected in all" "granulocytes: 1213.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041023, HPA041072" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA041023: AB_10794434, HPA041072: AB_10794262" "unprognostic (7.94e-2)" "prognostic favorable (4.92e-4)" "unprognostic (1.18e-2)" "prognostic favorable (1.54e-5)" "unprognostic (3.27e-1)" "unprognostic (4.03e-2)" "unprognostic (2.31e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-2)" "unprognostic (6.76e-2)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (8.12e-2)" "unprognostic (1.81e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-1)" "unprognostic (2.02e-1)" 2.6 2.3 0.5 13.4 0.6 1.7 1.2 0.8 1.0 1.0 0.7 5.1 1.7 0.4 0.2 0.6 1.1 0.3 0.7 0.6 0.5 0.8 5.5 7.4 3.9 1.0 0.7 0.4 0.9 0.7 0.5 3.3 0.9 0.9 1.5 0.2 2.0 1.6 0.2 0.5 2.7 0.5 0.5 29.8 1.3 0.2 0.6 2.2 0.6 0.9 1.2 2.3 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.5 303.9 46.2 0.7 357.2 0.8 3.8 0.5 0.9 233.9 0.5 0.9 1.2 1213.7 2.7 263.5 55.5 1.0 210.7 0.5 0.6 0.8 1.0 0.6 0.5 1.0 0.7 0.9 0.5 0.6 1.4 1.7 3.2 12.2 0.7 7.1 3.2 0.7 0.0 0.0 1.3 1.4 3.7 4.0 2.8 5.0 1.8 10.4 0.7 15.2 0.0 0.0 0.2 0.4 1.0 1.2 4.0 0.0 6.5 1.1 0.0 1.4 3.2 0.0 2.5 10.1 0.4 2.9 1.8 216.2 0.0 0.8 0.3 0.0 246.9 132.6 0.1 0.9 327.1 8.8 16.9 179.9 0.7 3.1 1.0 0.4 0.0 1.2 0.0 1.3 0.6 0.1 0.4 4.4 2.1 0.0 0.9 1.1 0.1 0.2 0.6 2.0 1.4 5.4 0.2 0.0 0.5 IGSF8 "CD316, CD81P3, EWI2, PGRL" ENSG00000162729 "Immunoglobulin superfamily member 8" Q969P0 1 160091340-160098943 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 155.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011917, HPA075970" Approved Supported Vesicles NA NA 280000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011917: AB_1851536, HPA075970: " "unprognostic (4.08e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.71e-1)" "unprognostic (1.01e-3)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.60e-2)" "unprognostic (2.35e-1)" "unprognostic (3.74e-3)" "unprognostic (1.75e-3)" 21.9 19.1 97.9 14.0 119.0 3.7 26.7 91.7 130.7 25.7 39.9 31.7 26.5 19.8 22.7 22.3 28.2 12.3 29.0 106.0 82.4 35.5 53.9 23.6 16.8 109.3 97.8 37.5 31.8 15.8 30.7 11.2 99.9 26.4 10.4 14.3 30.1 18.2 12.4 50.3 28.5 7.0 98.6 24.2 27.5 33.4 94.7 13.6 28.6 7.1 8.9 20.3 25.0 155.3 26.8 15.7 20.1 51.3 11.6 7.3 42.9 12.9 16.8 26.9 25.0 17.9 17.9 39.0 47.1 18.8 23.4 50.3 8.2 18.9 3.8 47.3 15.0 5.1 17.3 31.2 19.2 13.5 41.7 9.0 37.7 17.5 5.6 19.0 5.6 42.0 7.0 21.8 6.3 25.4 33.8 31.3 42.4 55.6 24.8 19.1 10.3 28.7 24.7 27.4 8.5 36.6 14.8 47.4 177.6 17.5 33.7 17.3 5.8 11.8 25.4 21.5 10.6 59.6 71.2 17.7 41.6 5.3 31.6 0.1 5.2 2.4 22.0 7.2 19.5 19.6 18.0 25.6 5.8 22.7 23.4 25.7 1.4 9.2 4.7 9.9 26.9 11.3 97.9 119.0 91.7 130.7 106.0 82.4 109.3 97.8 99.9 98.6 94.7 155.3 12.2 9.6 3.3 18.3 21.1 43.7 30.2 43.1 26.2 55.6 28.0 29.2 3.3 17.2 16.7 38.6 10.4 32.8 15.1 36.1 5.9 34.2 3.8 12.0 7.2 7.8 19.9 7.4 65.3 12.4 219.7 22.4 6.6 26.4 10.2 12.2 13.2 28.8 14.9 65.6 43.8 24.7 44.7 4.3 16.2 1.1 16.8 8.5 42.7 9.4 51.5 75.7 10.3 9.0 107.2 20.6 39.5 15.8 20.0 22.0 47.6 15.8 6.0 11.8 6.6 39.8 15.3 4.0 6.6 21.0 62.4 69.4 19.5 13.6 32.6 26.0 IKBKE "IKK-i, IKKE, KIAA0151" ENSG00000263528 "Inhibitor of nuclear factor kappa B kinase subunit epsilon" Q14164 1 206470476-206496889 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 47.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015788, CAB025983" Approved Supported Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "CAB025983: , HPA015788: AB_1851566" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.76e-2)" "unprognostic (7.78e-3)" "unprognostic (7.37e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (5.09e-3)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.34e-7)" "unprognostic (1.48e-2)" "unprognostic (5.77e-2)" "unprognostic (2.84e-3)" "unprognostic (2.84e-2)" 2.4 3.7 2.6 16.7 4.6 8.7 3.1 2.0 3.2 4.1 1.9 7.8 7.4 1.7 3.9 14.6 2.8 5.1 1.4 2.7 3.3 3.4 1.6 4.1 24.3 4.1 3.6 1.2 3.4 1.0 1.9 2.6 3.9 3.6 7.7 0.1 6.9 2.1 0.5 15.0 8.0 2.5 2.7 14.2 7.2 0.7 4.4 16.5 4.5 0.3 20.4 8.4 6.8 4.6 17.8 13.9 3.7 0.4 6.7 9.2 3.9 7.1 22.3 9.4 10.4 11.5 26.9 35.3 18.6 14.5 11.5 23.0 0.1 18.1 2.2 5.5 3.5 4.7 8.8 7.6 8.4 29.5 14.8 12.2 3.2 7.7 1.7 10.9 14.2 9.4 2.3 10.0 10.5 3.6 19.2 47.7 5.2 4.3 10.9 9.7 4.3 27.7 10.7 29.4 0.0 0.0 2.9 22.9 4.2 4.5 13.8 20.3 26.5 9.0 5.5 6.9 8.5 3.5 1.8 23.3 17.1 24.2 3.7 12.2 32.8 0.6 21.2 23.3 14.8 26.4 32.4 30.1 9.5 14.0 25.7 27.3 2.2 23.9 13.4 3.2 52.8 28.6 2.6 4.6 2.0 3.2 2.7 3.3 4.1 3.6 3.9 2.7 4.4 4.6 0.4 0.0 4.5 0.7 13.7 1.9 3.6 37.8 1.8 0.0 4.3 3.7 0.9 4.3 16.3 0.0 0.0 4.2 7.9 11.7 0.0 12.1 3.3 1.5 0.9 0.7 3.6 4.4 1.5 12.6 5.2 3.4 17.3 2.4 5.1 3.7 2.2 0.8 13.8 0.0 1.5 6.4 8.2 12.9 0.7 7.0 0.9 16.0 7.2 1.9 9.0 0.0 14.4 1.0 0.2 15.9 21.5 0.7 6.4 3.2 10.7 3.5 14.5 0.0 0.0 0.7 3.1 0.3 0.9 11.1 4.8 1.5 15.8 3.9 10.2 11.6 IKZF1 "hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1" ENSG00000185811 "IKAROS family zinc finger 1" Q13422 7 50304068-50405101 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "bone marrow: 173.0;lymphoid tissue: 112.5" "Cell type enhanced" "Detected in many" "B-cells: 120.5;dendritic cells: 221.4;Erythroid cells: 89.8;Microglial cells: 91.8;monocytes: 106.6;NK-cells: 150.4;Plasma cells: 128.9;T-cells: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 140.4;HDLM-2: 258.6;HMC-1: 220.4;JURKAT: 128.9;MOLT-4: 184.3;REH: 192.3;U-698: 342.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009247, HPA035221, HPA035222" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB009247: AB_2124699, HPA035221: AB_2674524, HPA035222: AB_2674525" "prognostic favorable (4.28e-4)" "prognostic favorable (2.02e-4)" "unprognostic (2.49e-3)" "unprognostic (2.41e-3)" "unprognostic (5.59e-1)" "prognostic favorable (8.63e-4)" "unprognostic (1.45e-2)" "unprognostic (1.37e-2)" "unprognostic (1.15e-2)" "unprognostic (2.43e-1)" "unprognostic (6.63e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-2)" "unprognostic (6.77e-2)" "unprognostic (4.67e-2)" 5.0 3.2 3.5 53.0 3.4 173.0 4.4 4.0 3.9 3.6 3.3 7.6 7.0 2.5 2.3 4.8 2.2 7.7 1.5 3.0 4.0 1.4 4.9 11.6 87.1 7.7 5.2 1.6 0.8 0.8 0.6 3.6 7.5 2.3 6.8 0.2 4.6 1.9 1.0 2.0 15.6 4.0 7.3 48.6 12.0 1.7 8.7 112.5 2.1 1.2 73.8 9.6 1.8 10.3 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.4 0.4 0.0 0.0 0.2 0.0 0.0 0.0 258.6 0.2 52.1 0.0 0.0 0.0 84.5 220.4 0.0 0.0 0.0 0.0 0.0 0.0 128.9 72.4 15.4 0.0 0.0 184.3 80.9 2.4 0.0 0.0 192.3 0.3 39.6 0.0 0.0 1.6 2.0 0.8 1.0 0.8 0.4 0.2 112.1 0.2 0.0 1.9 0.2 0.4 80.8 49.4 342.7 0.5 89.5 0.5 21.2 14.2 25.0 35.4 43.9 29.1 46.7 36.3 35.0 15.1 40.7 48.2 35.7 20.2 24.3 43.3 23.4 32.6 26.4 3.5 3.4 4.0 3.9 3.0 4.0 7.7 5.2 7.5 7.3 8.7 10.3 2.8 3.2 12.2 0.7 120.5 2.8 0.1 0.0 0.0 0.0 2.8 1.9 1.5 2.8 1.8 1.8 0.0 0.4 221.4 0.3 0.0 0.4 3.8 0.5 0.4 2.6 0.0 89.8 0.2 0.0 0.4 2.5 4.6 0.6 23.4 0.2 3.9 2.0 30.6 0.0 0.3 0.0 0.0 64.3 61.0 5.3 0.0 72.1 19.6 91.8 106.6 0.0 150.4 1.0 0.3 0.1 0.4 0.0 128.9 0.1 0.0 1.0 1.5 0.1 0.0 1.5 1.6 0.1 2.1 0.5 2.7 0.7 182.8 0.1 0.1 0.1 IKZF2 "Helios, ZNFN1A2" ENSG00000030419 "IKAROS family zinc finger 2" Q9UKS7 2 212999691-213152427 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.3" "Cell type enhanced" "Detected in many" "Astrocytes: 77.4;Oligodendrocyte precursor cells: 100.5;Oligodendrocytes: 78.3;Squamous epithelial cells: 47.8;Urothelial cells: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 4.8;NK-cells: 5.5;T-cells: 5.8" "Cell line enhanced" "Detected in many" "JURKAT: 70.5;MOLT-4: 31.1;RT4: 28.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059142 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA059142: AB_2683923" "unprognostic (2.29e-1)" "unprognostic (1.04e-1)" "unprognostic (7.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" "unprognostic (2.80e-3)" "unprognostic (2.98e-1)" "unprognostic (3.03e-1)" "unprognostic (5.12e-2)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.21e-1)" "unprognostic (3.56e-3)" "unprognostic (4.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.93e-3)" "unprognostic (7.09e-2)" 2.1 2.0 2.6 3.8 5.5 5.5 2.3 3.2 3.2 3.4 0.7 1.8 0.8 1.9 3.2 19.4 2.8 3.1 1.9 2.9 3.8 1.5 1.4 2.9 7.0 5.2 3.5 2.0 2.0 5.2 1.9 2.0 5.3 3.3 1.7 5.5 8.4 4.3 4.1 9.1 1.2 0.8 3.2 5.5 4.4 2.5 3.9 40.3 7.8 1.6 6.8 9.6 8.3 7.4 2.8 1.0 5.3 0.3 17.1 17.2 3.3 3.4 3.9 0.8 1.7 1.4 4.6 3.7 4.4 2.0 0.4 6.5 0.1 1.8 2.7 0.0 0.9 1.9 3.6 0.5 0.1 8.9 0.6 16.9 1.6 0.1 0.5 4.3 0.0 70.5 1.2 3.1 1.6 5.2 31.1 8.9 1.1 2.2 0.8 18.1 3.5 0.0 1.5 28.6 1.6 1.0 0.0 3.6 0.0 4.4 4.8 0.9 9.2 4.9 3.8 2.3 0.7 6.0 2.0 20.6 2.4 0.0 1.1 3.9 0.0 4.8 1.8 0.0 4.9 0.2 0.6 1.4 0.0 1.0 0.3 1.5 0.0 5.5 0.0 0.5 5.8 0.3 2.6 5.5 3.2 3.2 2.9 3.8 5.2 3.5 5.3 3.2 3.9 7.4 2.1 9.6 12.6 77.4 5.2 5.9 23.2 7.9 11.4 4.8 5.1 2.2 7.6 1.5 19.5 7.3 4.2 4.3 27.4 2.8 0.0 2.3 1.3 16.1 1.8 2.4 3.0 9.0 17.7 3.1 1.2 2.7 8.6 18.1 3.8 2.5 2.5 2.2 2.1 0.0 19.9 2.3 4.1 2.4 2.1 0.7 1.8 2.8 1.8 31.9 1.3 3.0 39.1 100.5 78.3 3.6 1.0 2.2 13.9 15.9 1.1 1.0 31.7 7.3 0.0 10.2 4.5 0.8 0.7 47.8 8.7 4.0 22.1 2.0 1.4 51.8 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.6;lymphoid tissue: 73.7" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Extravillous trophoblasts: 93.0;Kupffer cells: 190.7;Langerhans cells: 145.0;Macrophages: 128.6;monocytes: 175.7;NK-cells: 110.2;Plasma cells: 129.5;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.5;HDLM-2: 76.6;Karpas-707: 27.7;RPMI-8226: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 13.9 8.9 4.7 39.8 4.9 63.6 6.1 4.4 7.0 5.6 4.9 12.0 8.0 3.5 2.7 6.4 5.2 17.9 5.3 4.2 5.9 4.1 13.1 23.8 51.7 6.9 5.1 3.1 2.4 2.6 3.6 14.2 5.5 4.7 14.5 0.5 5.2 3.2 1.7 3.2 24.8 10.4 6.0 73.7 9.2 1.9 5.3 16.9 4.2 3.3 32.4 20.7 3.7 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 0.2 0.0 0.7 0.0 0.5 0.0 0.0 76.6 0.0 0.2 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.6 27.7 0.0 0.0 0.4 6.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 5.6 1.0 8.0 0.0 11.4 0.0 3.3 48.9 2.4 52.8 68.6 38.3 12.6 51.0 62.1 44.7 6.2 17.9 33.3 3.4 70.2 58.6 17.3 88.7 84.1 4.7 4.9 4.4 7.0 4.2 5.9 6.9 5.1 5.5 6.0 5.3 7.5 2.2 6.4 16.0 0.3 52.8 5.7 0.4 0.0 5.7 0.1 1.0 1.9 2.7 0.0 1.3 0.0 0.0 1.3 87.5 0.5 0.0 0.2 0.1 0.4 0.5 4.9 0.0 9.3 0.8 0.8 93.0 2.3 6.6 0.7 12.6 0.0 3.6 1.4 60.4 0.0 1.2 0.0 0.0 190.7 145.0 0.5 0.3 128.6 17.8 22.5 175.7 0.4 110.2 0.0 0.6 0.1 0.1 0.0 129.5 0.0 0.0 1.0 1.5 0.1 0.0 1.6 2.7 0.1 0.3 1.2 4.1 3.3 105.5 0.0 0.7 0.4 IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Kupffer cells: 13.9;NK-cells: 69.0;Plasma cells: 15.3;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 18.8;HDLM-2: 35.2;Karpas-707: 57.8;U-698: 15.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" 2.1 1.2 1.0 15.2 1.8 9.3 0.9 1.0 2.1 1.0 1.7 3.1 4.5 0.7 0.8 1.6 0.8 3.5 0.7 1.1 1.1 0.9 2.2 5.8 24.6 2.5 1.5 0.6 0.5 1.3 0.5 1.6 2.3 0.8 2.9 0.5 1.7 0.6 0.7 1.6 7.0 1.9 1.1 16.2 4.1 0.8 2.3 6.6 0.7 0.2 14.1 4.0 0.5 3.7 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.1 0.5 1.0 0.3 2.2 18.8 0.1 0.2 0.7 0.3 0.0 0.0 0.0 35.2 0.2 2.2 0.6 0.3 1.0 0.9 3.1 0.1 0.0 0.5 0.0 0.2 0.1 5.1 0.3 57.8 0.0 0.2 9.7 0.3 0.1 0.1 0.0 6.7 0.1 0.8 0.0 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.4 9.7 0.4 0.5 0.4 0.2 0.2 6.6 11.0 15.2 0.6 12.1 1.1 8.5 12.5 9.2 50.9 34.7 64.0 11.5 34.8 41.7 14.7 9.1 19.3 34.0 14.7 40.9 34.0 8.1 53.0 24.3 1.0 1.8 1.0 2.1 1.1 1.1 2.5 1.5 2.3 1.1 2.3 3.7 0.5 0.0 3.0 0.3 9.6 0.3 2.1 0.1 0.6 0.0 0.3 0.5 1.0 1.5 0.6 0.0 0.0 0.2 35.1 0.1 0.0 0.0 0.5 0.5 0.2 0.5 0.0 5.2 0.8 0.0 0.8 0.7 3.1 0.7 4.5 0.0 0.4 0.1 6.4 0.0 0.4 0.0 0.0 13.9 4.0 0.0 0.0 11.7 0.0 3.7 11.9 0.0 69.0 0.0 2.6 0.1 0.0 0.0 15.3 0.5 0.4 0.2 0.2 0.0 0.0 0.7 0.3 0.4 0.1 0.0 0.9 0.1 31.5 0.0 0.2 1.3 IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115694 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.9;Kupffer cells: 81.4;Macrophages: 61.4;monocytes: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HL-60: 59.9;NB-4: 52.5;THP-1: 74.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 62000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.92e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (9.83e-2)" "unprognostic (7.66e-2)" "unprognostic (5.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.96e-2)" "prognostic favorable (8.35e-4)" "unprognostic (2.16e-2)" "unprognostic (1.27e-1)" "unprognostic (6.51e-3)" 9.1 5.6 5.5 9.6 11.3 31.8 6.9 5.7 7.5 5.4 6.8 4.7 3.8 5.4 5.0 5.2 6.0 3.6 4.6 6.3 5.5 3.7 5.7 10.0 6.9 9.8 7.3 4.5 5.2 3.9 3.8 3.5 8.9 5.0 3.4 1.5 5.2 2.8 1.8 6.9 6.2 5.3 7.7 16.6 5.6 2.0 7.7 15.4 4.2 2.6 5.6 4.6 4.7 9.6 7.9 4.5 4.1 5.1 8.0 4.6 5.1 11.5 7.4 5.3 6.8 4.4 5.1 7.1 4.6 11.6 6.9 12.4 5.6 5.4 3.7 11.6 6.6 0.0 2.6 2.8 9.2 59.9 17.8 6.8 7.9 4.7 3.7 5.2 5.7 5.6 3.0 7.3 5.5 6.7 7.2 52.5 2.2 10.1 4.3 1.6 0.8 1.3 5.1 5.8 2.8 0.1 8.0 6.7 5.7 4.6 5.3 74.7 15.9 4.1 5.8 6.1 4.3 5.8 3.4 3.3 6.0 28.3 4.5 8.5 7.4 7.2 1.1 3.4 0.9 0.5 1.5 1.2 3.9 0.4 2.4 1.8 16.5 1.5 3.5 1.8 1.0 2.6 5.5 11.3 5.7 7.5 6.3 5.5 9.8 7.3 8.9 7.7 7.7 9.6 14.0 12.8 14.1 2.9 13.8 8.8 6.6 10.2 10.8 3.9 7.2 5.8 6.1 10.0 8.6 5.5 8.4 6.1 18.7 23.6 0.0 8.7 4.0 7.2 8.1 13.7 13.2 9.2 8.3 12.6 11.9 13.6 29.0 9.7 7.6 58.9 17.5 11.1 34.0 3.3 6.4 13.9 6.1 81.4 16.2 2.1 9.0 61.4 8.8 41.2 114.2 4.3 28.8 12.5 11.4 12.2 12.4 4.5 10.3 9.1 14.7 3.4 8.0 2.9 13.1 10.4 10.0 3.0 13.4 9.0 6.8 6.4 25.4 8.1 12.4 9.6 IL1RAP "C3orf13, IL-1RAcP, IL1R3" ENSG00000196083 "Interleukin 1 receptor accessory protein" Q9NPH3 3 190514051-190659750 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 225.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 109.2;Hepatocytes: 295.8;Oligodendrocyte precursor cells: 298.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "eosinophil: 23.8;neutrophil: 95.0" "Lineage enriched" "Detected in many" 15 "granulocytes: 95.0" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035293 Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 350000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "HPA035293: AB_10671511" "unprognostic (6.48e-2)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (8.84e-3)" "unprognostic (2.35e-2)" "unprognostic (6.60e-2)" "unprognostic (2.62e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.16e-7)" "unprognostic (4.02e-3)" "unprognostic (9.06e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.29e-4)" 6.2 2.9 4.0 11.4 1.1 20.3 4.3 0.0 8.7 4.4 0.5 2.2 1.8 4.0 2.6 13.1 5.4 12.1 3.9 4.6 3.1 3.3 225.8 8.2 2.7 2.4 3.7 3.0 3.9 1.5 1.2 37.0 3.3 3.9 2.2 2.4 5.2 3.4 1.3 11.9 2.2 6.4 1.5 5.4 4.5 1.3 5.5 4.6 4.0 2.1 4.8 9.4 5.5 3.3 13.3 3.0 5.5 0.8 9.5 7.7 10.0 5.8 11.9 13.4 13.2 5.8 29.3 2.2 59.2 16.4 31.1 34.1 3.0 57.6 18.7 2.5 3.6 2.9 5.3 14.5 19.6 20.2 9.5 10.3 23.1 19.7 59.2 27.8 6.0 5.9 0.4 0.2 6.4 6.5 1.7 9.4 8.5 6.0 6.0 9.5 8.2 4.8 5.3 14.8 1.0 0.0 26.3 15.0 247.1 5.2 9.6 14.6 7.9 10.3 10.4 32.1 26.6 5.0 0.2 0.5 17.2 18.0 60.9 11.7 3.8 23.8 1.8 4.3 3.3 2.1 2.1 2.3 3.8 2.1 2.0 1.3 95.0 0.3 6.3 0.6 2.1 1.4 4.0 1.1 0.0 8.7 4.6 3.1 2.4 3.7 3.3 1.5 5.5 3.3 3.5 0.0 14.7 6.5 6.8 44.7 16.5 45.8 68.9 6.5 2.5 4.7 5.5 40.0 22.8 3.7 8.4 8.5 3.6 1.8 0.0 7.7 4.4 8.6 3.8 8.0 5.4 4.4 44.3 7.5 109.2 7.3 7.1 12.3 7.6 0.7 7.5 295.8 7.8 0.0 63.3 1.4 4.1 33.7 17.7 0.6 4.4 28.8 8.8 53.4 5.0 1.0 6.2 298.6 1.5 19.7 0.8 2.6 5.3 11.5 0.7 1.1 8.7 0.6 0.0 18.0 5.1 0.1 0.6 30.9 37.2 24.2 5.2 1.4 1.1 14.3 IL1RL2 "IL1R-rp2, IL1RRP2" ENSG00000115598 "Interleukin 1 receptor like 2" Q9HB29 2 102187006-102240002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 12.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5.6;Excitatory neurons: 9.7;Glandular and luminal cells: 8.4;Langerhans cells: 7.1;Suprabasal keratinocytes: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.1;ASC TERT1: 5.1;HaCaT: 3.8;HSkMC: 4.4;hTCEpi: 2.3" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "unprognostic (6.70e-2)" "unprognostic (1.17e-1)" "unprognostic (6.57e-2)" "unprognostic (2.76e-4)" "unprognostic (3.42e-3)" "unprognostic (2.60e-1)" "unprognostic (3.13e-3)" "unprognostic (6.79e-2)" "unprognostic (9.10e-3)" "unprognostic (9.17e-2)" "unprognostic (4.61e-2)" "unprognostic (2.38e-1)" "unprognostic (1.05e-2)" "unprognostic (8.33e-3)" "unprognostic (3.80e-1)" "unprognostic (1.47e-1)" "unprognostic (7.65e-2)" 1.0 1.5 0.5 0.5 0.6 0.3 2.6 0.1 0.9 1.5 0.0 0.9 0.1 0.4 1.4 5.8 2.3 2.3 0.5 0.7 1.0 4.3 2.9 0.5 0.0 0.8 0.5 0.3 0.5 2.6 0.3 0.3 0.8 0.9 1.1 0.0 2.2 2.3 0.4 12.3 0.3 0.3 0.1 0.1 1.6 0.1 0.9 0.3 2.4 0.7 1.0 1.0 2.5 0.3 8.1 0.0 0.0 0.0 1.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 3.8 0.0 0.6 0.4 0.4 0.0 0.0 1.1 0.0 1.5 0.0 0.0 4.4 2.3 1.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.9 0.7 1.0 0.8 0.5 0.8 0.1 0.9 0.3 1.1 0.0 1.1 0.3 0.0 5.6 2.7 0.7 3.4 0.0 2.1 2.4 0.3 1.5 0.4 1.8 0.0 0.1 0.2 0.5 3.9 0.2 0.3 3.8 2.4 0.9 1.2 0.0 9.7 0.2 0.2 1.4 0.5 8.4 0.0 0.0 0.0 1.3 0.6 0.0 1.1 1.1 0.0 2.8 7.1 0.2 1.5 4.2 0.0 1.9 0.6 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 2.0 0.0 0.4 0.1 0.0 0.0 1.8 1.7 0.0 0.0 5.2 5.5 0.1 0.2 0.6 0.7 1.8 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 184.4;Hofbauer cells: 306.0;Langerhans cells: 292.6;Squamous epithelial cells: 469.7;Suprabasal keratinocytes: 336.6;Urothelial cells: 464.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cell line enhanced" "Detected in some" "A-431: 59.1;HaCaT: 112.3;RT4: 106.6;THP-1: 27.3" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 13.0 2.1 0.2 46.7 0.4 233.3 9.0 0.4 1.3 278.1 1.1 4.4 10.7 2.5 2.9 1969.7 2.1 17.0 2.5 0.3 0.3 1.6 248.5 20.1 1.4 0.4 0.5 0.9 1.8 2.0 2.3 21.1 0.8 2.4 4.0 0.0 287.1 7.5 0.8 128.6 8.8 3.9 0.8 14.7 45.5 6.4 1.3 5.2 6.4 3.0 311.7 185.7 465.0 0.6 59.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.2 0.0 0.6 0.2 0.2 0.0 1.1 112.3 0.0 3.3 0.0 0.1 0.0 0.3 0.0 17.3 0.0 0.3 20.3 0.0 14.3 0.7 0.0 2.0 0.0 0.0 0.3 0.3 0.0 0.5 0.1 14.7 0.0 13.2 0.0 0.0 0.1 0.1 0.0 106.6 0.0 0.0 0.1 0.8 0.1 0.0 0.0 27.3 0.3 1.4 0.0 0.7 0.1 0.6 0.1 0.2 10.3 10.5 0.3 0.0 63.8 1.9 0.0 27.7 0.0 0.1 0.0 0.0 61.7 0.1 0.1 0.1 240.2 0.0 13.7 0.8 0.1 19.8 0.2 0.4 0.4 1.3 0.3 0.3 0.4 0.5 0.8 0.8 1.3 0.6 1.7 6.4 7.7 0.0 4.1 184.4 81.3 151.8 56.9 0.0 4.9 3.4 0.4 11.5 60.6 3.7 0.0 1.8 0.2 6.5 0.0 27.5 34.8 7.8 1.4 4.8 0.0 3.2 0.3 28.0 2.9 11.0 44.4 23.6 10.1 0.0 3.3 53.0 306.0 0.0 0.2 1.1 6.1 39.8 292.6 93.3 0.6 111.1 24.9 0.0 22.6 0.0 2.1 0.5 0.2 149.9 0.1 0.4 2.8 58.4 9.3 0.2 20.2 0.0 0.0 0.3 3.8 0.8 0.2 469.7 336.6 4.5 3.3 0.0 3.2 464.9 IL20RB "DIRS1, FNDC6, IL-20R2, MGC34923" ENSG00000174564 "Interleukin 20 receptor subunit beta" Q6UXL0 3 136946230-137011085 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 110.7;skin 1: 163.3;vagina: 66.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 36.8;Basal respiratory cells: 115.8;Basal squamous epithelial cells: 60.9;Club cells: 43.0;Early spermatids: 57.0;Late spermatids: 28.8;Squamous epithelial cells: 56.5;Suprabasal keratinocytes: 38.1" "Group enriched" "Detected in many" 5 "cervical cancer: 54.5;head and neck cancer: 50.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 86.0;HBEC3-KT: 140.0;HHSteC: 91.8;hTCEpi: 555.6;hTERT-HME1: 102.6" "Not detected" "Not detected" HPA063914 Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Cytosol "HPA063914: AB_2732709" "unprognostic (1.35e-2)" "unprognostic (1.05e-1)" "unprognostic (7.43e-4)" "unprognostic (2.48e-4)" "unprognostic (2.74e-1)" "unprognostic (3.31e-1)" "unprognostic (7.43e-4)" "unprognostic (4.08e-3)" "unprognostic (7.64e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (3.57e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.55e-1)" "unprognostic (3.55e-2)" "unprognostic (1.33e-2)" "unprognostic (5.57e-2)" 2.3 0.2 0.1 0.0 0.2 0.0 10.3 0.1 0.6 24.3 0.1 0.6 0.0 0.2 0.0 110.7 0.4 0.0 0.6 0.1 0.1 0.2 5.4 0.5 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.4 0.2 2.2 0.5 0.0 13.6 0.2 1.0 163.3 0.4 0.0 0.1 0.3 0.5 3.7 0.2 2.0 0.5 0.9 9.5 1.3 66.2 0.2 27.2 0.0 0.1 0.4 15.4 64.9 2.6 0.6 1.8 0.3 1.2 2.7 3.4 0.2 14.9 9.7 1.0 86.0 0.0 140.0 0.7 0.4 0.0 0.3 19.5 0.0 91.8 0.2 0.2 11.5 555.6 4.5 102.6 0.7 0.1 0.1 0.3 0.1 0.0 0.0 0.6 0.0 0.4 2.4 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.0 54.6 0.0 2.8 4.7 0.5 0.9 0.0 0.2 1.8 0.5 0.5 0.1 0.2 0.2 8.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.7 0.0 0.0 0.7 0.0 36.8 1.7 115.8 60.9 0.0 0.3 0.5 0.4 0.0 43.0 0.0 0.0 1.7 0.8 0.8 0.0 0.9 57.0 0.7 0.4 0.9 0.0 0.0 1.0 0.2 1.4 3.9 0.0 0.8 0.0 0.2 0.0 2.2 0.4 0.0 1.2 0.7 10.2 0.3 6.6 28.8 0.3 0.6 3.6 1.0 1.7 0.0 1.0 1.0 0.2 1.0 0.1 0.7 0.4 1.3 0.2 0.3 5.5 0.0 0.0 0.6 3.6 1.7 1.9 56.5 38.1 1.6 0.6 0.2 0.5 5.3 IL31RA "CRL, CRL3, GLM-R, Glmr, IL-31RA" ENSG00000164509 "Interleukin 31 receptor A" Q8NI17 5 55851357-55922854 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.6;lymphoid tissue: 2.1;testis: 1.8" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Late spermatids: 1.2;Spermatocytes: 2.5;Syncytiotrophoblasts: 1.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 26.3;HBEC3-KT: 10.3;HHSteC: 9.5;hTERT-HME1: 11.5;U-2 OS: 16.8;U-87 MG: 20.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "HPA051532, HPA068114" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA051532: , HPA068114: AB_2732779" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.13e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-3)" "unprognostic (7.34e-2)" "unprognostic (3.54e-1)" "unprognostic (5.38e-2)" "unprognostic (2.95e-3)" "unprognostic (7.75e-5)" "unprognostic (5.55e-2)" "unprognostic (2.65e-6)" "unprognostic (7.73e-2)" "unprognostic (7.68e-2)" "unprognostic (4.02e-1)" "unprognostic (1.76e-2)" 0.0 0.0 0.1 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.1 1.8 0.0 2.1 0.0 0.6 0.1 0.1 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.4 0.5 0.2 0.5 0.3 0.1 0.0 0.2 0.0 0.0 0.4 26.3 0.0 0.0 10.3 2.2 0.0 0.1 0.0 0.0 0.0 9.5 0.0 0.0 7.3 2.9 4.8 11.5 0.6 4.1 0.1 0.0 0.4 1.4 0.0 0.0 1.2 0.0 0.0 6.8 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.5 2.0 0.5 16.8 0.0 0.8 0.0 0.0 0.0 20.8 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.3 0.3 0.0 0.0 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.1 2.5 0.6 0.0 0.1 1.1 0.0 0.7 0.0 0.0 IL34 "C16orf77, IL-34, MGC34647" ENSG00000157368 "Interleukin 34" Q6ZMJ4 16 70579895-70660682 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.3;skin 1: 62.0" "Cell type enhanced" "Detected in many" "Leydig cells: 18.3;Peritubular cells: 40.6;Sertoli cells: 19.7;Suprabasal keratinocytes: 20.5;Theca cells: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 13 "eosinophil: 18.5" "Lineage enriched" "Detected in single" 185 "granulocytes: 18.5" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.1;Hep G2: 2.7;HSkMC: 2.4;NTERA-2: 5.3;U-138 MG: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 57100 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (3.76e-3)" "prognostic favorable (7.41e-4)" "unprognostic (5.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.27e-2)" "prognostic favorable (9.69e-4)" "unprognostic (8.19e-2)" "unprognostic (1.59e-3)" "unprognostic (3.83e-2)" "unprognostic (6.11e-3)" "unprognostic (3.18e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.52e-8)" "unprognostic (6.47e-3)" "unprognostic (4.58e-2)" "unprognostic (5.83e-2)" "unprognostic (4.37e-2)" 4.4 22.9 17.1 3.9 18.1 0.1 8.6 8.5 23.3 9.6 23.1 4.0 5.1 2.9 1.0 25.5 3.2 6.7 4.4 22.5 14.5 5.7 2.5 5.0 9.1 13.0 11.7 1.6 1.9 1.0 12.5 0.5 14.1 6.2 2.2 1.2 16.0 3.8 9.6 62.0 6.4 2.5 10.1 106.3 2.4 3.5 19.0 3.9 5.1 2.5 5.0 4.8 13.4 11.6 0.0 0.6 0.1 0.1 0.2 2.1 0.2 0.1 1.8 0.2 0.2 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.9 0.0 1.6 2.4 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.3 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.3 0.0 0.0 0.0 3.6 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.7 0.1 1.4 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 18.1 8.5 23.3 22.5 14.5 13.0 11.7 14.1 10.1 19.0 11.6 2.8 0.0 1.8 2.9 0.1 8.3 1.6 3.4 2.2 1.2 15.7 14.7 0.4 1.5 4.9 0.0 4.2 0.1 0.5 0.0 0.0 7.4 0.2 0.5 0.3 6.1 0.0 0.0 12.7 2.0 0.9 9.0 0.0 0.1 0.0 0.0 3.6 0.1 3.8 5.0 11.4 0.1 2.0 0.0 4.2 0.3 18.3 0.4 12.4 5.6 0.0 15.2 0.0 1.5 1.0 0.8 0.1 40.6 0.1 2.4 0.2 0.3 1.2 0.8 19.7 2.0 8.1 0.1 0.4 7.8 20.5 0.8 0.3 18.8 0.5 1.9 IL36B "FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882" ENSG00000136696 "Interleukin 36 beta" Q9NZH7 2 113022089-113052867 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 2.2;lymphoid tissue: 3.8;skin 1: 8.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "GAMG: 71.8;U-87 MG: 73.3" "Not detected" "Not detected" HPA035664 Uncertain "Secreted to blood" NA NA 15300 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "HPA035664: AB_10669672" "unprognostic (8.45e-2)" "unprognostic (1.62e-1)" "unprognostic (3.56e-2)" "unprognostic (1.06e-1)" "unprognostic (3.77e-2)" "unprognostic (2.40e-3)" "unprognostic (2.05e-1)" "unprognostic (7.10e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 1.4 0.0 0.0 0.0 0.0 73.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL36G "IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1" ENSG00000136688 "Interleukin 36 gamma" Q9NZH8 2 112973203-112985658 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 14.3;lymphoid tissue: 39.4;skin 1: 31.3" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 136.0;Club cells: 36.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 36.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.1;HaCaT: 1.0" "Not detected" "Not detected" HPA068168 Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Nucleoplasm, Plasma membrane" "HPA068168: " "unprognostic (1.56e-2)" "unprognostic (2.88e-1)" "unprognostic (7.27e-2)" "unprognostic (3.15e-2)" "unprognostic (4.91e-2)" "unprognostic (1.92e-1)" "unprognostic (3.68e-1)" "unprognostic (3.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (5.79e-2)" "unprognostic (5.58e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 3.9 0.2 0.0 31.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 39.4 0.8 3.6 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 136.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.7 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 3.9 0.0 0.0 0.0 1.3 0.2 0.0 1.7 13.2 0.0 0.0 0.0 0.0 7.8 IL36RN "FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840" ENSG00000136695 "Interleukin 36 receptor antagonist" Q9UBH0 2 113058638-113065382 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 26.5;lymphoid tissue: 43.7;skin 1: 60.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.9;Extravillous trophoblasts: 2.0;Syncytiotrophoblasts: 3.8" "Cancer enriched" "Detected in some" 7 "head and neck cancer: 25.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BEWO: 26.6;GAMG: 11.1;U-87 MG: 19.9" "Not detected" "Not detected" "Secreted to blood" NA NA 107000 "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (3.88e-3)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (4.29e-1)" "unprognostic (8.68e-3)" "unprognostic (9.80e-2)" "unprognostic (2.48e-1)" "unprognostic (5.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" "unprognostic (5.37e-2)" "unprognostic (3.85e-3)" "unprognostic (4.23e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 3.4 0.0 0.0 0.0 0.0 4.6 0.0 0.1 60.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 43.7 0.0 9.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.1 1.1 0.3 0.0 0.0 11.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 3.8 0.0 0.0 0.0 0.7 IL37 "FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7" ENSG00000125571 "Interleukin 37" Q9NZH6 2 112912971-112918882 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 136.8" "Cell type enriched" "Detected in some" 26 "Ionocytes: 73.2" "Cancer enriched" "Detected in some" 6 "lung cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.7;PC-3: 5.9;RT4: 3.2" "HPA054371, HPA057950" Uncertain Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA 76700 "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "HPA054371: AB_2682465, HPA057950: AB_2683561" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.71e-5)" "unprognostic (1.11e-1)" "unprognostic (2.58e-2)" "unprognostic (1.09e-2)" "unprognostic (1.28e-2)" "unprognostic (9.54e-2)" "unprognostic (8.26e-3)" "unprognostic (3.95e-2)" "unprognostic (1.66e-1)" "unprognostic (8.92e-2)" "unprognostic (1.35e-2)" 0.1 0.0 0.0 0.2 0.0 0.2 16.7 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 0.4 136.8 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.1 0.2 2.7 0.2 0.2 0.2 0.3 0.0 0.2 0.1 0.2 0.1 0.1 0.4 0.8 0.1 0.0 1.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.2 0.2 5.9 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 73.2 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 2.8 0.0 0.1 0.0 0.0 0.0 IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.0;dendritic cells: 137.5;Endothelial cells: 83.2;Langerhans cells: 47.6;monocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cell line enhanced" "Detected in many" "HDLM-2: 128.8;NB-4: 24.9;RPMI-8226: 54.1" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" 25.2 2.9 7.1 15.8 13.6 25.0 20.6 16.1 11.7 6.4 0.2 8.1 5.5 8.7 1.6 5.4 8.0 11.3 13.0 5.9 8.1 9.2 1.8 25.0 25.1 11.7 10.6 8.8 5.4 3.4 2.8 6.2 11.1 7.0 6.6 22.0 9.5 3.2 12.1 12.7 9.2 12.3 7.5 11.1 6.9 3.5 10.1 4.4 10.3 8.6 13.0 12.4 6.3 20.5 0.2 9.4 3.6 1.3 0.1 0.0 1.1 1.2 0.3 0.0 0.1 0.9 1.5 1.2 7.2 0.2 0.6 9.6 0.0 0.0 0.0 128.8 3.9 0.6 2.1 0.4 0.0 0.8 15.6 0.0 0.0 0.0 0.0 4.1 8.2 0.9 0.3 6.1 0.0 1.4 0.7 24.9 3.1 0.8 0.5 1.4 4.2 54.1 0.0 1.4 0.6 0.4 0.6 0.3 2.8 1.8 1.2 17.8 0.4 0.5 1.5 0.5 0.3 12.5 3.9 1.1 9.8 2.8 0.1 2665.0 5.6 83.9 0.6 31.7 1.0 2.5 0.9 0.5 14.9 8.9 0.7 0.7 4.6 14.2 42.5 628.5 0.5 12.0 7.1 13.6 16.1 11.7 5.9 8.1 11.7 10.6 11.1 7.5 10.1 20.5 79.0 3.2 1.8 11.8 6.8 5.9 0.7 0.9 1.2 2.3 0.5 0.9 2.2 1.5 1.0 0.0 10.4 0.1 137.5 4.7 0.0 0.4 0.2 2.7 1.4 83.2 0.0 3.0 7.3 0.2 0.1 4.3 0.5 1.5 11.4 0.4 24.3 0.7 4.6 0.0 14.3 7.3 0.0 2.8 47.6 0.1 0.3 32.9 8.8 13.1 72.6 0.6 1.0 6.0 18.2 0.1 3.4 0.7 4.0 0.7 0.2 0.0 0.4 3.2 0.0 3.6 3.2 0.1 0.7 0.7 5.5 0.3 1.6 1.3 0.6 2.1 IL5RA "CD125, CDw125, IL5R" ENSG00000091181 "Interleukin 5 receptor subunit alpha" Q01344 3 3066324-3126613 "CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.0;fallopian tube: 10.7" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 28.0;granulocytes: 19.0;Plasma cells: 9.9;Respiratory ciliated cells: 13.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 192 "basophil: 178.4;eosinophil: 355.1" "Lineage enriched" "Detected in many" 255 "granulocytes: 355.1" "Cell line enriched" "Detected in some" 28 "HMC-1: 71.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 910000 "Cluster 2: Granulocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.38e-3)" "unprognostic (2.26e-2)" "unprognostic (2.66e-1)" "unprognostic (6.13e-3)" "unprognostic (2.66e-1)" "unprognostic (1.54e-3)" "unprognostic (7.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.83e-1)" "unprognostic (1.67e-1)" "unprognostic (9.84e-4)" "unprognostic (4.32e-3)" "unprognostic (3.08e-2)" "unprognostic (6.95e-2)" "unprognostic (2.20e-1)" "unprognostic (7.49e-2)" "unprognostic (4.93e-2)" 0.2 0.2 0.8 0.6 0.7 0.6 1.0 0.6 0.3 1.0 9.0 0.7 1.7 0.4 0.2 0.5 10.7 0.7 1.0 0.8 1.2 0.4 0.1 2.7 0.4 5.0 4.6 0.1 0.4 0.0 1.5 0.1 3.2 1.8 1.1 0.0 0.7 0.1 0.4 0.1 1.6 0.3 4.5 1.8 1.1 1.1 1.2 0.5 0.2 0.0 1.5 1.7 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 2.5 71.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 178.4 0.1 355.1 0.9 0.1 0.1 0.4 1.0 0.7 0.1 1.3 0.3 0.7 1.0 0.0 0.1 0.1 0.1 0.7 0.8 0.7 0.6 0.3 0.8 1.2 5.0 4.6 3.2 4.5 1.2 0.9 0.2 0.0 2.5 0.0 4.8 0.1 0.0 0.3 0.0 0.0 0.0 0.0 2.3 1.5 1.4 0.0 0.0 0.1 2.8 0.0 0.0 0.0 2.4 28.0 0.3 0.1 0.0 0.8 0.7 0.0 0.0 0.2 0.0 0.5 19.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.0 0.3 5.7 0.0 0.1 5.4 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 9.9 0.8 0.0 0.1 13.9 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.1 IL7R "CD127, IL7RA" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.7" "Group enriched" "Detected in many" 4 "monocytes: 271.8;T-cells: 973.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2" "Group enriched" "Detected in all" 33 "NK-cells: 113.2;T-cells: 369.5" "Cell line enhanced" "Detected in many" "BJ: 99.8;BJ hTERT+ SV40 Large T+: 87.7;fHDF/TERT166: 187.7;HBF TERT88: 168.3;REH: 406.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" NA NA 610000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" 11.2 14.4 1.5 137.6 1.8 14.0 20.4 7.4 2.7 12.0 1.0 17.3 15.0 3.9 1.6 11.0 5.7 32.4 2.2 2.0 2.5 4.5 12.5 63.9 139.4 1.8 0.5 2.2 5.3 0.8 1.7 2.9 1.6 8.7 20.4 0.9 3.3 3.1 4.1 3.8 56.8 5.6 0.6 70.1 34.1 4.7 4.4 183.7 7.6 1.7 123.0 48.0 7.1 6.2 0.6 0.4 0.7 0.4 0.7 0.6 0.6 99.8 50.6 87.7 51.3 0.5 0.6 9.6 0.3 187.7 15.9 16.0 0.2 6.0 168.3 8.6 1.1 3.2 10.3 0.0 1.5 0.6 7.2 1.6 0.0 18.7 4.3 2.4 2.6 0.7 0.7 0.9 71.3 0.2 2.3 1.0 0.3 0.3 4.6 406.2 5.2 0.6 0.0 5.3 0.4 0.2 15.9 1.7 0.2 0.3 0.6 0.4 7.0 34.5 58.4 14.8 13.4 0.6 0.2 10.4 17.4 9.2 27.8 4.3 1.6 1.0 102.1 1.2 369.5 1.5 213.8 151.1 0.7 2.1 179.5 124.6 7.3 113.2 1.5 1.8 39.7 87.7 1.5 1.8 7.4 2.7 2.0 2.5 1.8 0.5 1.6 0.6 4.4 6.2 8.9 16.0 16.0 0.0 47.4 11.6 2.7 0.0 5.2 0.0 8.6 6.1 4.9 0.0 2.5 0.0 0.0 0.2 136.0 0.6 0.0 1.0 0.1 1.1 0.4 13.2 0.0 16.4 0.0 2.0 0.2 11.6 53.5 1.2 19.6 0.2 13.2 4.4 10.6 0.0 0.0 0.5 0.0 10.6 98.5 0.8 0.0 58.8 21.4 2.8 271.8 0.0 11.3 0.0 0.0 0.1 1.4 0.0 93.5 1.4 0.0 0.8 5.8 0.0 0.0 5.5 7.9 0.2 0.1 1.5 10.4 0.3 973.8 0.4 0.4 3.5 IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030877 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 359.1;skeletal muscle: 257.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 440.3;Extravillous trophoblasts: 272.2;Proximal tubular cells: 498.6;Squamous epithelial cells: 202.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 26.0;neutrophil: 31.3" "Group enriched" "Detected in many" 11 "dendritic cells: 9.0;granulocytes: 31.3;monocytes: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 258.2;OE19: 299.8;SiHa: 155.1" "Low region specificity" "Detected in all" HPA029561 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Mitochondria "HPA029561: AB_10601932" "unprognostic (1.16e-1)" "unprognostic (1.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.50e-2)" "unprognostic (4.25e-2)" "unprognostic (3.25e-3)" "unprognostic (4.26e-3)" "unprognostic (4.08e-2)" "unprognostic (1.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.56e-2)" "unprognostic (4.24e-3)" "prognostic favorable (0.00e+0)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (3.35e-2)" 19.8 11.1 2.5 12.3 3.2 31.5 14.8 1.8 4.4 31.0 5.3 50.0 22.4 16.2 1.7 131.2 16.3 19.9 29.5 2.5 2.4 129.4 47.4 23.2 5.7 2.2 2.4 7.8 359.1 5.3 11.1 22.0 2.1 13.7 30.7 0.8 31.0 5.9 257.1 150.0 29.2 15.6 2.3 19.0 53.7 2.9 2.6 5.0 17.4 89.8 7.3 61.0 50.8 2.3 29.3 41.7 11.3 20.4 14.1 10.5 258.2 7.2 18.4 2.9 4.2 35.4 21.7 6.1 17.4 10.1 24.1 19.8 13.2 6.9 0.8 33.5 22.5 0.0 56.0 30.6 8.3 47.5 2.3 23.9 36.3 10.0 5.2 8.5 3.9 30.7 7.4 0.0 10.7 31.8 19.4 27.1 40.5 299.8 42.7 36.0 29.6 28.6 122.1 15.6 15.0 0.3 155.1 35.8 16.2 14.5 33.3 58.5 0.0 5.6 11.5 73.7 7.3 24.5 66.3 17.9 24.0 31.7 9.6 9.4 11.4 26.0 0.7 8.7 0.3 1.5 0.7 0.2 9.0 0.3 0.3 0.5 31.3 0.1 5.8 6.7 1.1 3.1 2.5 3.2 1.8 4.4 2.5 2.4 2.2 2.4 2.1 2.3 2.6 2.3 9.2 19.2 32.7 17.6 7.8 105.5 22.7 32.1 159.4 0.7 16.8 20.2 11.6 72.9 16.1 22.0 0.0 52.5 5.8 72.9 440.3 83.4 2.8 5.7 20.2 6.9 17.5 15.3 4.7 110.6 272.2 16.1 65.2 30.4 2.5 13.4 10.0 66.8 42.5 0.0 1.8 90.2 65.1 37.7 17.0 7.1 4.7 34.2 14.2 5.6 25.5 22.3 2.1 0.5 0.5 56.1 50.1 3.8 8.6 42.9 36.9 498.6 12.3 1.0 105.2 16.0 27.6 0.8 10.1 202.1 141.4 106.3 6.1 14.0 84.4 52.8 INAVA "C1orf106, FLJ10901" ENSG00000163362 "Innate immunity activator" Q3KP66 1 200891048-200915742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 44.2;intestine: 55.4;skin 1: 47.0" "Cell type enhanced" "Detected in some" "Ductal cells: 33.3;Endometrial ciliated cells: 26.8;Exocrine glandular cells: 45.5;Glandular and luminal cells: 25.1;Pancreatic endocrine cells: 118.6;Proximal tubular cells: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 60.3;CAPAN-2: 49.6;HaCaT: 66.0;OE19: 57.8;RPMI-8226: 54.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA027499, HPA027511, HPA079622" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Nuclear bodies" "HPA027499: AB_10599708, HPA027511: AB_10600334, HPA079622: " "unprognostic (3.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.78e-5)" "unprognostic (4.56e-2)" "unprognostic (2.18e-1)" "unprognostic (2.74e-2)" "unprognostic (6.62e-3)" "unprognostic (2.84e-2)" "unprognostic (9.38e-2)" "unprognostic (2.52e-2)" "unprognostic (2.81e-1)" "unprognostic (3.23e-3)" "unprognostic (1.67e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.73e-2)" 0.1 0.0 1.4 4.0 1.4 4.5 1.7 0.8 1.3 8.8 1.8 33.8 47.3 1.1 0.5 44.2 4.2 16.3 0.2 1.4 1.4 15.3 0.4 3.5 0.4 1.1 1.4 0.1 13.2 0.1 0.3 1.9 1.0 7.0 30.1 0.4 12.3 2.6 0.2 47.0 55.4 1.1 1.0 0.3 27.3 1.1 1.5 0.9 0.1 0.0 5.7 17.1 20.3 1.0 27.5 40.8 23.3 0.0 0.0 0.0 60.3 0.0 0.0 0.7 0.5 43.4 49.6 0.0 13.3 0.0 1.1 66.0 0.0 17.4 0.5 0.0 5.0 3.8 1.8 17.2 0.1 8.5 0.8 0.0 26.1 0.4 1.1 0.6 0.0 0.0 0.0 0.0 0.2 0.4 0.1 1.4 45.2 57.8 9.2 0.2 9.7 54.0 24.4 34.9 0.1 2.8 2.6 41.5 0.0 27.3 17.1 7.9 0.0 0.1 10.1 0.1 2.9 46.2 20.6 0.0 0.1 8.6 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.4 1.4 0.8 1.3 1.4 1.4 1.1 1.4 1.0 1.0 1.5 1.0 0.6 12.8 7.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.5 3.3 0.0 0.0 5.0 14.7 0.0 7.6 0.1 0.0 5.9 33.3 0.0 26.8 2.2 0.7 0.0 0.0 0.0 45.5 13.2 0.4 0.0 25.1 1.3 0.7 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 118.6 0.0 0.0 0.0 0.0 0.0 26.0 4.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.1 0.5 0.3 0.0 0.0 INKA1 "C3orf54, FAM212A" ENSG00000185614 "Inka box actin regulator 1" 3 49803261-49805030 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 24.1" "Cell type enhanced" "Detected in some" "Adipocytes: 19.9;Breast myoepithelial cells: 9.7;Endothelial cells: 8.4;Hofbauer cells: 54.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 59.6;memory B-cell: 65.9;naive B-cell: 64.4" "Group enriched" "Detected in many" 7 "B-cells: 65.9;granulocytes: 59.6" "Cell line enhanced" "Detected in many" "HEL: 68.5;HMC-1: 45.1;NB-4: 38.5;THP-1: 42.1;U-937: 34.9" "Low region specificity" "Detected in all" HPA041879 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Vesicles" "HPA041879: AB_10797269" "unprognostic (1.36e-1)" "unprognostic (2.99e-2)" "unprognostic (6.97e-2)" "unprognostic (7.95e-2)" "unprognostic (1.34e-1)" "prognostic favorable (1.96e-4)" "unprognostic (2.70e-2)" "unprognostic (4.35e-2)" "unprognostic (7.28e-2)" "unprognostic (2.94e-1)" "unprognostic (3.35e-3)" "unprognostic (4.61e-2)" "unprognostic (1.90e-3)" "unprognostic (4.95e-2)" "unprognostic (3.90e-2)" "unprognostic (1.45e-1)" "unprognostic (1.40e-2)" 5.1 2.3 4.8 2.0 5.0 3.5 4.1 5.2 7.6 6.2 2.8 3.2 0.8 4.7 1.4 19.7 2.8 1.5 5.2 5.3 5.5 5.8 1.1 5.4 4.1 6.2 5.3 2.2 1.3 0.5 2.1 3.1 5.7 6.4 0.5 0.2 4.9 2.1 11.7 24.1 4.3 1.8 5.8 6.7 2.4 2.9 6.5 1.6 2.1 2.3 3.9 5.5 10.3 7.0 1.3 1.1 1.5 1.1 1.8 4.1 0.0 3.0 1.9 1.4 1.7 0.1 0.0 14.9 0.4 2.2 1.5 8.7 0.5 10.4 0.1 2.6 0.0 68.5 0.7 0.2 2.6 10.4 45.1 5.4 14.5 2.9 2.6 0.9 6.1 1.0 4.7 1.2 1.2 0.6 0.9 38.5 1.1 0.0 5.8 13.9 0.8 3.3 0.1 16.9 0.8 5.3 2.7 0.5 1.5 0.4 0.3 42.1 3.8 7.3 0.9 3.4 1.3 1.7 1.7 1.2 3.2 34.9 1.8 59.6 2.4 11.6 1.3 5.9 0.3 65.9 1.5 1.8 0.7 64.4 2.2 3.6 1.3 0.0 8.5 9.3 1.6 6.4 4.8 5.0 5.2 7.6 5.3 5.5 6.2 5.3 5.7 5.8 6.5 7.0 19.9 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.0 9.7 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.7 0.0 0.5 1.6 8.4 0.0 0.0 0.0 1.2 0.7 3.0 0.0 0.1 0.0 0.1 0.0 0.0 54.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 3.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.1 0.4 0.5 0.0 0.0 INO80C "C18orf37, FLJ38183, hIes6, IES6" ENSG00000153391 "INO80 complex subunit C" Q6PI98 18 35452230-35497979 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 184.7;Pancreatic endocrine cells: 165.1;Spermatocytes: 209.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049060 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center" "HPA049060: AB_2680617" "unprognostic (3.40e-1)" "prognostic favorable (3.58e-4)" "unprognostic (2.29e-1)" "prognostic unfavorable (2.62e-5)" "unprognostic (5.56e-2)" "unprognostic (9.68e-2)" "unprognostic (1.72e-3)" "unprognostic (2.03e-1)" "unprognostic (3.32e-3)" "unprognostic (2.08e-3)" "unprognostic (2.61e-1)" "unprognostic (6.94e-3)" "unprognostic (1.18e-1)" "unprognostic (5.82e-2)" "unprognostic (1.44e-2)" "unprognostic (5.14e-3)" "unprognostic (5.38e-2)" 18.0 17.4 23.2 14.5 24.4 46.2 16.0 24.9 23.7 18.4 30.9 21.1 18.4 12.0 13.6 45.7 13.7 13.0 25.6 23.2 31.1 21.8 19.2 17.5 26.2 22.2 23.1 9.8 13.3 8.0 29.2 20.7 24.2 13.9 21.8 33.6 20.7 9.2 42.4 40.5 18.6 11.0 21.0 31.2 30.4 92.2 31.5 21.9 15.2 30.7 29.2 21.4 20.8 23.6 46.5 30.1 27.1 14.9 9.5 23.6 29.7 17.5 13.2 27.3 36.5 37.5 38.7 77.4 36.6 11.9 41.6 31.3 52.4 112.7 24.8 22.9 28.3 97.8 36.0 40.7 21.0 57.4 60.1 10.7 31.9 70.7 37.9 33.7 80.0 32.3 30.4 27.8 44.7 49.3 36.4 48.5 34.6 32.2 18.0 28.5 19.2 26.5 58.4 58.9 37.3 25.8 27.9 31.6 23.4 41.8 31.5 46.1 51.5 30.9 13.5 24.0 32.3 24.1 28.4 137.8 25.2 52.7 19.2 21.3 14.8 35.6 12.3 20.6 12.2 24.9 17.0 16.3 22.2 17.8 17.2 14.2 23.0 12.4 18.3 33.5 21.7 11.8 23.2 24.4 24.9 23.7 23.2 31.1 22.2 23.1 24.2 21.0 31.5 23.6 40.2 6.4 10.1 5.9 19.5 24.0 22.1 72.3 18.8 4.4 16.3 15.2 17.8 18.6 31.6 12.9 4.2 59.8 14.0 81.4 31.3 43.9 184.7 16.7 6.6 30.5 15.0 29.0 15.6 40.0 105.1 14.1 41.8 14.4 20.3 9.0 22.1 16.6 52.2 5.0 11.3 20.4 36.7 17.9 15.0 49.6 6.2 16.4 23.2 6.5 14.1 22.8 14.4 9.0 10.9 165.1 76.0 7.2 26.4 20.7 48.8 80.9 31.5 14.1 0.0 18.5 15.6 209.0 40.3 35.3 39.9 73.2 16.4 11.9 35.9 34.7 INPP4A INPP4 ENSG00000040933 "Inositol polyphosphate-4-phosphatase type I A" Q96PE3 2 98444854-98594392 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 150.5;Inhibitory neurons: 124.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001628 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Nuclear membrane" "HPA001628: AB_10961254" "unprognostic (3.45e-1)" "unprognostic (2.39e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.70e-6)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "unprognostic (1.15e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (9.65e-2)" "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (4.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" 8.7 8.2 15.9 13.2 19.5 12.7 6.1 18.8 22.0 7.0 1.0 11.3 7.3 7.5 5.2 7.7 6.6 9.9 10.5 15.9 9.9 5.2 4.1 9.6 17.2 9.2 3.5 7.0 6.6 8.9 7.7 8.1 9.2 6.0 7.9 10.7 5.6 6.3 8.4 4.1 8.8 9.8 4.7 16.7 7.3 5.9 5.9 20.3 5.9 11.6 12.5 10.8 5.5 10.1 12.7 11.0 18.2 14.8 10.4 11.1 19.2 10.0 9.4 10.9 11.3 14.6 11.5 7.8 13.3 15.4 14.0 12.6 12.6 11.1 8.5 27.7 10.9 9.5 9.7 6.5 8.8 17.3 34.3 9.9 9.9 10.6 9.0 9.5 15.1 44.9 8.5 67.4 8.3 16.2 26.3 16.8 17.6 7.4 11.3 12.0 12.5 51.9 5.6 41.6 12.8 15.7 12.1 10.1 9.5 18.7 4.8 13.8 14.3 12.7 17.9 10.1 7.5 50.2 31.1 5.8 10.5 16.2 11.5 1.1 1.0 2.3 2.8 2.2 3.3 0.4 1.6 1.8 1.1 0.1 2.2 2.5 1.1 3.2 3.4 3.3 0.9 1.0 15.9 19.5 18.8 22.0 15.9 9.9 9.2 3.5 9.2 4.7 5.9 10.1 14.6 6.4 13.1 50.9 11.2 8.0 6.4 2.8 9.1 49.7 5.3 4.2 12.6 2.8 7.8 5.5 8.4 10.2 64.6 4.1 3.9 4.0 13.5 6.2 9.1 14.2 5.4 7.2 150.5 1.5 8.7 9.9 6.6 6.3 0.0 22.4 14.3 3.4 10.5 33.7 124.4 5.6 4.1 36.4 18.4 10.9 9.3 25.3 10.6 73.1 26.8 8.4 71.1 55.8 26.1 3.8 2.5 12.0 48.6 5.9 1.2 3.3 5.1 14.1 6.6 9.9 12.4 8.6 14.0 5.2 6.1 9.4 48.3 9.4 3.6 6.8 INSC ENSG00000188487 "INSC spindle orientation adaptor protein" Q1MX18 11 15112424-15247208 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 25.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.9;Early spermatids: 4.6;Exocrine glandular cells: 3.1;Oligodendrocyte precursor cells: 8.0;Pancreatic endocrine cells: 10.9;Proximal tubular cells: 8.9" "Cancer enhanced" "Detected in some" "melanoma: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 11.7;hTERT-HME1: 6.0;Karpas-707: 3.3;LHCN-M2: 3.6;TIME: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA039769 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039769: AB_10697556" "unprognostic (1.64e-2)" "unprognostic (6.54e-2)" "unprognostic (1.45e-3)" "unprognostic (1.59e-1)" "unprognostic (6.00e-2)" "unprognostic (4.59e-3)" "unprognostic (6.88e-2)" "unprognostic (3.44e-3)" "unprognostic (3.69e-1)" "unprognostic (3.59e-2)" "unprognostic (2.63e-1)" "unprognostic (2.31e-1)" "unprognostic (3.30e-3)" "unprognostic (2.31e-1)" "unprognostic (1.35e-1)" "unprognostic (2.50e-2)" "unprognostic (5.00e-2)" 0.2 0.8 0.2 1.0 0.1 0.6 0.2 0.1 0.2 1.1 0.1 4.7 2.1 0.1 0.1 0.5 0.3 0.6 1.2 0.1 0.2 0.3 0.2 0.9 0.0 0.3 0.2 0.1 0.9 25.3 0.2 0.0 0.2 1.0 1.8 0.0 0.5 1.0 0.0 0.1 3.0 0.5 0.2 0.1 2.4 0.7 0.1 0.2 0.3 0.1 0.0 0.8 0.8 0.2 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.4 0.0 0.0 0.0 0.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.5 0.6 6.0 0.0 0.0 0.0 0.0 3.3 3.6 0.0 0.0 0.2 0.0 0.1 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 1.0 0.0 0.0 1.5 0.2 0.0 0.5 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.9 0.1 4.6 0.2 0.0 0.1 1.8 0.0 0.5 3.1 0.0 0.9 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.0 0.0 10.9 0.0 0.0 0.1 0.2 0.0 8.9 0.0 0.0 0.0 0.0 1.1 1.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 2.6 IPPK "C9orf12, FLJ13163, INSP5K2, IP5K, IPK1" ENSG00000127080 "Inositol-pentakisphosphate 2-kinase" Q9H8X2 9 92613183-92670131 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 31.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020603 Uncertain Approved Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA020603: AB_1851853" "unprognostic (3.51e-2)" "unprognostic (4.66e-2)" "unprognostic (6.26e-2)" "unprognostic (1.26e-1)" "unprognostic (3.63e-2)" "unprognostic (2.08e-1)" "unprognostic (4.88e-2)" "unprognostic (3.13e-2)" "unprognostic (4.40e-2)" "unprognostic (1.10e-1)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.26e-9)" "unprognostic (1.28e-2)" "unprognostic (4.23e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.28e-4)" 5.4 6.9 5.2 4.5 5.7 8.5 6.4 7.5 6.4 9.1 3.9 4.1 3.2 5.2 4.8 31.6 5.4 4.6 7.8 6.9 4.7 4.4 5.3 4.7 5.7 5.5 5.1 5.4 3.6 8.5 8.1 5.5 5.7 4.2 4.4 5.7 8.8 2.8 7.6 29.8 4.2 5.4 5.0 5.4 4.6 11.6 5.6 5.9 4.6 6.1 8.7 5.7 15.5 5.6 19.3 10.1 9.2 8.0 11.1 8.2 30.4 13.5 8.5 13.6 7.8 6.3 7.4 11.9 6.6 18.9 12.0 27.1 16.4 18.9 11.3 14.9 10.4 9.8 21.9 9.9 7.8 16.7 11.2 8.1 18.4 16.3 12.7 12.4 10.3 9.8 13.5 14.1 13.6 26.3 9.6 7.7 15.8 21.2 14.9 8.5 9.8 4.9 8.0 11.5 19.1 11.2 10.9 44.9 7.8 8.9 10.6 4.2 19.7 10.0 11.3 28.2 14.4 13.0 16.2 6.5 13.0 7.5 9.9 0.0 1.4 3.4 3.6 1.8 4.1 2.4 3.0 3.1 2.1 2.2 2.3 2.6 2.1 0.8 1.9 2.3 4.6 1.9 5.2 5.7 7.5 6.4 6.9 4.7 5.5 5.1 5.7 5.0 5.6 5.6 6.8 3.2 3.4 10.1 4.8 25.4 6.4 7.6 16.5 7.5 6.0 4.7 0.4 1.5 5.1 1.8 6.2 10.8 4.6 5.0 5.9 6.2 11.0 8.3 5.3 6.8 6.7 6.1 23.8 8.0 13.8 4.1 7.1 10.2 0.0 3.6 10.0 3.1 5.1 15.2 23.7 3.5 6.1 7.5 4.6 33.7 3.1 5.3 3.6 7.5 2.8 4.9 8.2 20.6 23.3 9.1 1.4 3.0 6.0 6.4 2.6 3.6 2.6 4.6 6.6 3.9 3.5 20.0 19.4 25.5 29.5 22.8 6.0 4.4 3.7 10.5 IQGAP2 ENSG00000145703 "IQ motif containing GTPase activating protein 2" Q13576 5 76403285-76708132 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 113.1" "Cell type enhanced" "Detected in many" "Early spermatids: 1011.9;Late spermatids: 351.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 21.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 74.2;Hep G2: 61.7;HMC-1: 211.8;RPMI-8226: 81.6;U-937: 57.0" "Region enhanced" "Detected in many" "hippocampal formation: 30.5" "Low region specificity" "Detected in all" "CAB004241, HPA037403, HPA037404" Uncertain Approved "Vesicles,Plasma membrane" NA NA 3700000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "CAB004241: AB_2125909, HPA037403: AB_2675459, HPA037404: AB_2675460" "unprognostic (9.46e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (9.03e-3)" "unprognostic (8.85e-2)" "prognostic favorable (5.65e-4)" "unprognostic (5.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.34e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "prognostic favorable (9.44e-12)" "unprognostic (3.29e-2)" "unprognostic (9.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.27e-2)" 7.9 12.2 0.8 11.7 0.6 25.0 27.1 0.5 0.7 19.6 2.4 25.7 56.5 3.3 9.5 2.8 3.4 18.6 2.9 0.4 0.9 35.2 113.1 9.9 14.4 2.2 2.5 8.9 25.7 44.3 1.1 30.7 1.9 15.2 23.0 23.9 34.6 15.4 0.3 2.7 31.4 4.3 1.4 13.2 39.1 51.1 2.4 7.3 28.6 1.3 8.2 6.5 1.5 2.4 0.0 9.6 31.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 74.2 0.1 0.7 2.7 0.0 2.7 0.2 12.1 0.0 0.1 8.6 12.0 27.6 6.8 61.7 0.2 15.7 211.8 0.0 0.0 0.0 0.0 0.0 1.2 14.9 24.6 21.4 0.0 0.0 13.5 42.4 14.8 25.4 0.3 4.9 0.1 81.6 0.0 0.1 0.6 3.2 17.3 0.9 0.1 31.4 0.0 9.3 0.4 0.0 0.5 0.0 0.3 19.8 0.0 18.7 0.1 57.0 3.0 21.3 3.1 1.9 4.5 2.5 3.7 0.5 4.7 3.9 2.9 0.2 1.8 3.3 6.0 4.3 3.4 7.7 6.2 1.4 0.8 0.6 0.5 0.7 0.4 0.9 2.2 2.5 1.9 1.4 2.4 2.4 9.1 12.8 12.2 0.7 27.3 4.7 21.5 2.4 0.0 6.7 68.9 34.5 3.5 107.2 9.1 35.0 108.4 14.2 230.3 96.2 7.9 44.5 1011.9 43.8 3.3 7.7 9.1 76.3 2.3 66.7 1.2 22.0 99.4 37.5 94.9 8.7 18.5 235.7 65.9 1.7 19.0 52.9 61.1 132.6 63.3 351.0 7.5 141.3 16.0 47.8 63.4 14.0 114.4 0.5 1.1 18.7 37.5 5.3 148.3 21.5 87.1 65.2 16.1 121.8 0.0 3.9 3.5 25.5 11.4 1.2 3.8 7.3 112.1 82.7 43.7 6.5 IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 11.2;Late spermatids: 26.6;Undifferentiated cells: 7.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA030142: AB_10600108, HPA030143: AB_10601104" "unprognostic (9.99e-3)" "unprognostic (5.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.55e-3)" "unprognostic (1.52e-1)" "unprognostic (4.69e-3)" "prognostic unfavorable (8.94e-6)" "unprognostic (1.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.30e-2)" "unprognostic (6.81e-2)" 0.7 0.7 0.2 2.2 0.4 15.5 0.6 0.0 0.6 1.1 0.2 4.1 6.6 0.5 1.1 5.2 0.2 0.7 0.4 0.5 0.1 0.6 0.6 1.6 1.6 0.9 0.4 0.1 0.2 0.1 0.1 2.8 0.9 0.4 5.0 0.0 1.0 0.1 0.3 3.7 5.7 2.9 0.0 0.8 4.6 3.8 0.6 3.4 0.2 0.0 2.2 0.9 2.1 0.4 59.2 28.4 25.6 18.1 1.6 4.0 12.4 43.1 28.3 41.0 36.6 32.4 52.5 5.2 15.6 25.2 21.6 54.6 17.5 22.1 36.3 0.1 15.7 7.8 62.6 16.1 0.2 9.7 0.1 1.2 2.5 34.3 50.0 10.0 24.1 12.5 16.1 8.1 30.2 31.2 5.7 13.7 18.6 57.7 28.0 18.9 28.8 6.1 10.4 20.3 16.3 25.2 38.7 44.9 14.9 29.8 35.8 25.6 16.8 36.8 43.7 30.4 51.4 4.0 2.1 2.4 12.4 15.1 42.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.2 0.4 0.0 0.6 0.5 0.1 0.9 0.4 0.9 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.4 1.3 0.1 0.4 0.6 0.0 1.4 1.3 1.0 2.8 0.1 0.0 0.0 2.2 0.1 3.9 0.0 0.3 6.5 0.5 0.7 0.6 1.2 6.5 0.7 0.0 3.6 0.9 11.2 1.4 0.0 4.4 2.5 0.4 3.9 0.0 0.2 3.7 0.0 1.3 6.1 26.6 0.3 1.9 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.5 0.4 0.8 0.4 0.0 0.0 0.0 0.0 1.4 6.4 2.6 3.6 1.0 0.8 0.2 0.3 7.4 0.4 IRF6 "LPS, OFC6, VWS, VWS1" ENSG00000117595 "Interferon regulatory factor 6" O14896 1 209785617-209806175 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 95.4;skin 1: 114.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 387.2;Basal prostatic cells: 253.9;Basal squamous epithelial cells: 217.9;Squamous epithelial cells: 251.9;Suprabasal keratinocytes: 552.4;Urothelial cells: 290.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 10.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 61.9;HaCaT: 210.7;HBEC3-KT: 80.5;hTCEpi: 170.1;hTERT-HME1: 82.2;RT4: 78.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063121, HPA076162" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA063121: AB_2684942, HPA076162: AB_2686780" "unprognostic (2.59e-1)" "unprognostic (1.79e-3)" "unprognostic (1.74e-1)" "unprognostic (7.80e-2)" "unprognostic (1.33e-2)" "unprognostic (4.94e-3)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (7.82e-2)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (2.70e-1)" "unprognostic (2.66e-2)" "unprognostic (2.14e-1)" "unprognostic (4.42e-2)" 1.6 11.4 1.6 3.2 1.5 2.8 35.9 10.9 1.8 21.6 5.2 27.1 26.9 5.9 49.3 95.4 21.7 10.8 29.7 1.7 1.4 17.0 33.3 8.8 0.9 1.9 2.9 1.9 19.7 26.4 6.5 20.4 1.9 32.4 31.5 2.4 39.0 26.4 0.5 114.0 25.0 2.0 2.1 2.1 24.8 2.9 2.3 20.3 17.1 2.7 23.0 40.5 46.8 1.2 61.9 0.0 0.0 0.0 0.4 0.0 20.9 0.1 0.5 0.1 0.3 13.6 20.7 0.0 0.1 0.1 0.0 210.7 0.0 80.5 0.0 0.0 1.3 0.1 0.2 0.0 0.2 0.0 0.2 0.1 170.1 0.1 82.2 0.0 3.7 0.0 0.1 0.2 0.0 8.3 0.0 0.3 1.2 17.0 0.2 0.0 0.0 0.3 7.7 78.8 18.7 6.1 1.4 34.1 1.9 3.8 24.1 0.3 0.0 0.0 0.1 0.0 0.3 0.8 15.8 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.6 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 1.6 1.5 10.9 1.8 1.7 1.4 1.9 2.9 1.9 2.1 2.3 1.2 1.9 16.0 10.4 0.3 1.0 387.2 253.9 154.0 217.9 0.1 47.2 33.3 26.0 32.9 70.4 35.0 0.0 94.2 1.3 95.5 27.4 36.7 1.1 120.2 9.5 6.0 59.9 0.4 0.0 19.2 25.4 4.5 53.0 121.7 2.5 0.0 1.1 35.9 8.3 0.0 0.1 74.9 38.7 1.0 30.1 0.7 0.6 2.3 35.6 1.9 1.0 6.5 0.0 0.0 0.0 49.2 43.8 0.0 2.5 153.9 49.5 11.9 82.1 0.6 0.0 0.4 7.4 8.2 3.7 251.9 552.4 161.6 2.5 0.7 44.5 290.3 IRX5 IRX-2a ENSG00000176842 "Iroquois homeobox 5" P78411 16 54930865-54934485 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Vision" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 14.0;skin 1: 16.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 40.3;Breast myoepithelial cells: 55.5;Granulosa cells: 43.8;Muller glia cells: 43.1;Squamous epithelial cells: 33.9" "Cancer enhanced" "Detected in many" "breast cancer: 20.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.1;T-47d: 36.6;THP-1: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA047130 Approved "Nuclear speckles,Microtubules,Cytosol" No NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "Microtubules, Cytosol" "HPA047130: AB_10962983" "unprognostic (2.63e-1)" "unprognostic (4.49e-2)" "unprognostic (8.03e-2)" "unprognostic (8.56e-2)" "unprognostic (1.42e-2)" "unprognostic (3.89e-2)" "unprognostic (5.38e-3)" "prognostic favorable (4.59e-4)" "unprognostic (8.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (1.17e-3)" "unprognostic (3.34e-2)" "unprognostic (8.90e-2)" "unprognostic (1.77e-3)" "unprognostic (4.28e-2)" 1.7 0.6 1.3 0.0 1.5 0.0 14.0 4.1 0.4 1.8 0.3 0.2 0.0 0.1 0.0 7.2 0.2 0.1 9.8 0.3 1.9 6.9 0.0 6.4 0.0 3.6 4.1 0.3 0.1 0.3 0.4 0.0 3.1 3.4 0.0 1.3 10.2 0.2 1.4 16.9 0.0 0.0 3.6 0.0 2.6 0.7 4.6 0.3 0.1 1.1 0.0 0.6 5.9 3.5 0.8 0.5 8.6 3.2 3.1 0.6 0.4 3.3 8.2 1.1 0.8 1.9 0.8 0.0 0.7 4.5 0.3 8.4 3.0 3.6 0.6 6.0 4.1 0.9 3.4 0.0 0.1 2.0 3.3 0.8 15.1 5.4 2.3 1.5 0.0 4.8 0.5 0.0 6.2 3.3 9.6 12.3 0.1 1.3 2.4 5.0 4.4 0.5 27.1 0.2 2.9 3.0 1.4 7.3 3.9 0.0 36.6 20.2 0.5 5.9 0.2 4.2 1.3 3.6 2.3 2.9 9.6 3.9 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 4.1 0.4 0.3 1.9 3.6 4.1 3.1 3.6 4.6 3.5 2.4 9.6 21.9 0.0 0.1 8.3 9.7 6.7 15.9 8.6 40.3 55.5 11.1 0.0 15.4 0.0 0.0 0.2 1.0 0.2 0.0 0.3 1.0 9.6 1.2 1.6 0.0 0.0 0.0 0.6 0.0 5.3 7.7 12.2 0.0 43.8 0.0 0.0 0.2 1.7 0.0 0.8 4.1 0.0 2.7 2.4 0.0 0.6 5.4 0.0 0.0 43.1 0.0 0.0 0.0 2.9 0.3 0.0 0.3 4.8 0.0 1.5 13.0 1.9 0.0 8.3 5.2 0.7 2.8 33.9 8.0 0.0 0.4 0.0 0.5 8.5 IRX6 "IRX-3, IRX7" ENSG00000159387 "Iroquois homeobox 6" P78412 16 55324203-55330756 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.8;heart muscle: 9.8;skin 1: 8.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.5;Collecting duct cells: 5.5;Hofbauer cells: 4.7;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HEK 293: 1.9;RPTEC TERT1: 7.1;SK-MEL-30: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018332 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" "HPA018332: AB_1851920" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (4.93e-4)" "unprognostic (2.48e-2)" "unprognostic (6.50e-2)" "unprognostic (3.46e-1)" "prognostic favorable (3.34e-4)" "unprognostic (3.63e-2)" "unprognostic (4.36e-2)" "unprognostic (2.93e-2)" "unprognostic (1.50e-2)" "unprognostic (2.83e-2)" "unprognostic (9.63e-3)" "unprognostic (7.12e-3)" "unprognostic (5.48e-2)" "unprognostic (5.23e-3)" 9.8 0.1 0.2 0.0 0.6 0.0 4.8 1.1 0.3 2.3 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.1 9.8 0.0 1.1 2.7 0.0 1.8 0.1 0.5 0.8 0.2 0.1 1.7 0.2 0.1 0.6 0.2 0.0 1.6 1.9 0.0 2.8 8.9 0.3 0.1 0.2 1.3 0.0 0.4 0.6 2.2 0.6 1.3 1.1 0.0 0.5 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.1 0.0 1.1 4.8 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 1.1 0.3 0.0 1.1 0.5 0.8 0.6 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.1 0.8 0.0 0.5 0.0 7.5 0.4 0.6 1.3 0.0 1.2 5.5 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.8 0.0 0.6 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.7 5.1 0.0 0.1 3.6 0.0 0.6 1.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.3 0.1 0.5 0.0 1.0 0.1 0.0 0.0 0.0 0.0 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.6" "Cell type enhanced" "Detected in many" "Adipocytes: 264.1;Endothelial cells: 120.5;Hepatocytes: 110.5;Sertoli cells: 98.6;Smooth muscle cells: 143.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.5;HHSteC: 4.5;SH-SY5Y: 1.7;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain NA NA 6300000 "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" 13.9 22.4 0.6 1.0 0.8 0.0 10.2 0.7 0.9 5.1 0.4 36.6 1.1 16.3 2.5 5.7 9.9 2.2 10.6 0.5 0.8 11.0 17.1 22.1 0.8 0.8 0.8 3.6 3.1 2.1 2.3 5.8 0.8 12.6 2.7 0.1 2.3 7.2 4.6 2.3 12.5 5.8 0.8 27.9 16.6 0.8 0.8 0.2 9.7 2.5 0.4 17.9 5.1 0.9 0.0 0.0 0.3 0.0 1.4 0.4 0.1 0.3 1.3 0.3 0.7 0.7 0.0 0.0 0.1 4.5 0.5 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.3 0.3 4.5 0.0 0.0 0.7 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 1.7 0.5 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.7 0.9 0.5 0.8 0.8 0.8 0.8 0.8 0.8 0.9 264.1 54.5 26.8 2.9 1.7 3.2 4.7 1.5 2.8 1.8 3.6 13.8 12.6 5.7 8.7 5.5 2.1 1.5 2.9 5.5 1.9 3.0 21.3 7.7 41.8 120.5 16.4 5.3 3.6 5.4 16.8 40.2 6.1 22.1 10.1 1.0 77.1 110.5 2.2 0.0 19.5 14.0 0.0 7.2 8.2 6.1 9.3 5.6 7.2 63.7 9.1 0.4 0.0 1.5 4.2 19.6 7.7 8.2 2.9 3.2 6.5 15.1 6.3 2.0 98.6 18.6 143.9 0.9 1.1 0.5 3.1 3.4 46.0 13.6 14.0 2.3 ITGA8 ENSG00000077943 "Integrin subunit alpha 8" P53708 10 15513954-15719922 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 37.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.8;Inhibitory neurons: 56.1;Microglial cells: 34.7;Oligodendrocyte precursor cells: 64.8;Plasma cells: 25.5;Sertoli cells: 52.6;Smooth muscle cells: 57.6" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;HMC-1: 19.8;HSkMC: 8.7;U-266/84: 9.7" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 14.1" HPA003432 Approved Approved "Plasma membrane" NA NA 200000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003432: AB_1851825" "unprognostic (2.15e-1)" "unprognostic (1.22e-3)" "unprognostic (1.05e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (8.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "unprognostic (6.82e-2)" "unprognostic (3.80e-1)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (4.10e-3)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (2.26e-1)" "unprognostic (6.03e-2)" 8.6 10.5 1.6 2.1 2.1 0.1 2.7 1.9 5.0 23.8 8.0 6.1 6.7 9.7 5.5 9.8 8.8 6.7 7.7 7.0 0.9 10.0 0.7 20.8 3.2 1.5 2.8 5.7 0.8 4.7 3.2 0.2 1.1 37.4 6.1 1.6 1.8 30.8 2.9 3.3 6.8 9.1 1.5 19.9 19.3 0.6 1.5 1.0 5.6 6.9 4.4 15.7 9.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 8.4 2.5 0.0 0.0 0.0 0.0 19.8 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.7 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.1 1.9 5.0 7.0 0.9 1.5 2.8 1.1 1.5 1.5 2.2 1.2 0.0 1.3 0.7 2.4 1.0 1.9 0.0 0.6 6.3 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 4.0 11.4 0.0 0.0 82.8 0.0 0.0 10.1 0.0 0.2 0.0 0.0 4.2 0.0 0.1 0.0 56.1 0.0 0.0 0.0 1.8 0.1 0.9 0.5 1.8 34.7 0.0 13.6 0.0 64.8 4.0 0.0 0.0 0.0 25.5 1.5 0.0 0.0 0.0 0.3 52.6 11.3 57.6 0.0 0.2 0.4 1.1 0.0 1.2 0.1 0.1 1.4 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Group enriched" "Detected in some" 6 "dendritic cells: 51.7;granulocytes: 31.8;NK-cells: 42.2;Plasma cells: 34.0;T-cells: 115.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 10 "JURKAT: 62.2;MOLT-4: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 1.0 0.3 0.0 15.9 0.0 3.7 0.9 0.0 0.0 1.0 0.0 1.4 0.7 0.4 0.0 1.4 0.4 4.2 0.2 0.0 0.0 0.3 1.6 3.1 29.3 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.4 1.5 0.0 0.3 0.1 0.0 0.2 4.0 0.5 0.0 10.5 3.1 0.5 0.0 57.9 0.5 0.0 24.6 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 3.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 62.2 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 39.6 0.0 26.4 0.0 55.6 54.9 0.1 0.0 78.2 65.0 1.3 29.3 2.3 0.1 73.2 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 4.0 2.7 0.6 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.6 1.8 0.0 0.1 51.7 0.1 0.0 0.1 8.5 0.2 0.3 0.8 0.0 1.7 0.2 0.0 0.0 1.1 7.7 0.4 31.8 0.1 1.8 1.0 0.0 0.0 0.2 0.0 0.0 1.6 5.1 6.7 0.0 2.9 1.8 1.0 2.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.2 3.4 0.1 115.7 0.0 0.1 0.6 ITPRID1 "CCDC129, FLJ38344" ENSG00000180347 "ITPR interacting domain containing 1" Q6ZRS4 7 31514071-31658720 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 15.9;salivary gland: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA024103 Uncertain Uncertain Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 9: U-2 OS - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "HPA024103: AB_1846132" "unprognostic (1.11e-2)" "unprognostic (1.39e-1)" "unprognostic (1.57e-1)" "unprognostic (1.78e-5)" "unprognostic (9.72e-3)" "unprognostic (1.78e-1)" "unprognostic (3.89e-2)" "unprognostic (6.42e-3)" "unprognostic (1.01e-1)" "unprognostic (5.77e-2)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.99e-1)" "unprognostic (1.53e-1)" 0.1 0.0 2.7 0.1 3.9 0.1 1.6 11.0 0.4 1.7 0.0 0.5 1.1 0.6 0.1 0.0 0.0 0.1 0.0 0.7 9.7 0.1 0.0 0.0 0.0 4.8 15.9 0.0 0.1 0.0 0.1 0.0 9.2 0.1 0.1 0.1 5.3 0.0 0.0 2.3 0.5 0.6 1.4 0.0 0.4 1.3 13.2 0.0 0.0 0.0 0.1 0.0 0.0 5.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 3.9 11.0 0.4 0.7 9.7 4.8 15.9 9.2 1.4 13.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 472.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 23.7;Hepatocytes: 25.1;Intestinal goblet cells: 21.8;Paneth cells: 22.5;Proximal enterocytes: 89.1;Proximal tubular cells: 35.4" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CACO-2: 1.3;OE19: 3.0;SK-BR-3: 3.2" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA059627: AB_2684086" "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" 0.1 0.0 0.4 0.6 0.3 0.3 0.5 0.6 0.6 0.1 0.2 6.4 18.1 0.2 0.6 0.0 0.0 8.9 0.5 0.3 0.1 26.6 33.6 0.7 0.5 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.2 6.5 0.2 0.1 0.0 0.0 0.2 19.6 0.2 0.0 0.1 2.0 0.2 0.5 0.0 472.7 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 3.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.5 0.3 0.2 0.4 0.2 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.9 0.7 0.2 0.3 0.2 1.3 0.4 0.3 0.6 0.6 0.3 0.1 0.5 0.4 0.6 0.0 0.5 0.5 0.7 3.2 7.8 0.0 0.0 0.1 0.6 0.2 0.0 0.1 0.3 0.4 0.8 14.3 8.9 0.0 0.0 0.1 0.0 23.7 1.9 0.3 0.0 0.9 0.3 0.4 3.6 2.7 0.1 0.2 0.0 0.7 0.0 2.2 1.3 0.1 1.1 25.1 0.1 0.0 0.1 21.8 0.0 0.0 1.2 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 22.5 0.0 0.0 1.0 89.1 35.4 3.6 1.3 0.0 1.7 0.3 0.1 0.1 0.0 0.4 0.3 0.9 0.4 11.5 0.7 JAM2 "C21orf43, CD322, JAM-B, JAMB, VE-JAM" ENSG00000154721 "Junctional adhesion molecule 2" P57087 21 25639258-25717562 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 63.5" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Astrocytes: 81.6;Endothelial cells: 148.7;Hepatic stellate cells: 112.8;Microglial cells: 82.4;Oligodendrocyte precursor cells: 76.9" "Cancer enriched" "Detected in all" 9 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.5;BJ hTERT+: 16.5;HDLM-2: 16.7;hTERT-RPE1: 22.5;U-138 MG: 18.1;U-87 MG: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028789, HPA077346" Supported "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA028789: AB_2732443, HPA077346: AB_2732341" "unprognostic (1.42e-1)" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.51e-4)" "unprognostic (2.61e-2)" "unprognostic (4.55e-1)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.81e-1)" "unprognostic (8.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.18e-1)" "unprognostic (2.20e-1)" "unprognostic (4.85e-3)" 20.5 15.8 16.6 3.7 21.5 0.3 16.8 24.0 21.8 16.8 12.8 17.8 6.1 18.5 11.2 7.1 16.1 12.9 19.2 19.2 22.0 9.2 2.2 15.5 3.6 25.9 23.1 16.1 2.8 4.3 8.1 63.5 21.3 9.4 7.9 7.1 6.1 15.4 7.8 5.5 10.7 19.6 26.8 1.6 10.2 17.6 25.2 2.6 10.3 13.2 5.0 11.6 13.2 23.0 0.0 0.0 25.5 0.1 1.0 0.2 0.5 0.8 16.5 2.0 7.6 0.0 0.0 0.1 0.0 0.2 9.7 0.1 2.2 0.0 4.6 16.7 0.7 0.1 0.1 0.1 0.0 0.1 0.1 1.4 0.0 1.8 0.1 22.5 0.0 0.6 0.0 0.2 8.0 0.0 0.4 0.1 8.1 0.2 0.0 3.2 5.3 0.1 0.0 0.0 0.4 3.7 0.2 0.3 0.0 0.3 0.9 0.2 0.0 18.1 1.7 0.1 2.5 1.8 0.1 0.0 13.4 0.1 0.7 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.4 0.6 0.1 0.4 0.0 0.1 16.6 21.5 24.0 21.8 19.2 22.0 25.9 23.1 21.3 26.8 25.2 23.0 173.8 0.0 2.3 81.6 0.9 7.5 1.4 0.0 2.2 1.4 1.4 9.1 33.2 0.0 0.0 3.7 14.6 0.3 0.5 0.0 0.0 0.2 16.5 1.0 4.7 148.7 0.0 0.0 15.2 0.2 5.3 28.5 0.5 2.1 0.0 4.5 112.8 0.5 1.3 0.0 45.0 0.0 0.0 1.8 10.7 15.6 9.9 2.8 16.0 82.4 0.0 1.8 0.0 76.9 4.1 0.1 0.0 24.5 1.2 1.5 0.0 0.0 0.7 5.2 0.0 5.7 7.0 6.7 4.4 0.8 6.7 0.8 1.6 2.1 0.0 1.2 JARID2 JMJ ENSG00000008083 "Jumonji and AT-rich interaction domain containing 2" Q92833 6 15246069-15522042 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.8" "Cell type enhanced" "Detected in all" "Langerhans cells: 195.0" "Cancer enhanced" "Detected in all" "testis cancer: 34.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 73.8;SuSa: 78.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063889, CAB069890" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Mitochondria" "CAB069890: AB_10000529, HPA063889: AB_2685143" "unprognostic (5.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (4.87e-3)" "unprognostic (6.35e-2)" "unprognostic (2.57e-2)" "unprognostic (1.30e-2)" "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (3.26e-3)" "unprognostic (7.04e-2)" "unprognostic (4.48e-2)" "unprognostic (2.78e-2)" "unprognostic (1.99e-1)" 7.3 4.7 6.7 9.2 7.1 57.8 6.0 23.6 8.7 5.3 3.7 5.0 5.7 5.0 6.7 13.7 3.9 4.4 6.4 7.5 6.2 4.1 3.6 7.2 9.0 7.1 6.8 5.7 3.5 3.6 4.4 7.1 7.8 4.5 4.6 20.0 6.4 3.3 11.8 13.4 6.8 4.1 5.2 10.6 7.0 16.0 8.0 20.0 3.8 4.3 9.8 5.8 6.8 8.2 12.4 8.5 34.0 19.6 4.1 4.0 33.5 3.5 8.3 4.5 5.5 8.8 9.4 6.5 12.3 7.1 6.8 6.3 8.0 20.1 4.1 13.0 12.4 23.3 10.6 11.6 4.6 23.9 26.3 5.7 12.3 6.6 26.2 13.4 4.7 73.8 30.5 10.8 2.7 12.6 47.6 44.6 36.4 6.1 3.8 20.9 10.4 18.6 4.2 13.0 26.2 15.0 7.3 24.9 32.1 78.1 8.7 25.0 8.5 20.6 11.4 11.5 12.3 6.9 17.8 11.7 7.0 21.9 26.6 10.1 3.8 3.2 3.4 2.4 2.9 2.5 1.6 2.1 3.1 3.4 2.1 2.9 13.2 4.9 2.7 4.4 1.4 2.1 6.7 7.1 23.6 8.7 7.5 6.2 7.1 6.8 7.8 5.2 8.0 8.2 30.1 6.4 12.8 175.3 40.7 80.4 10.7 23.0 31.9 74.2 28.3 23.1 10.5 15.7 17.1 5.5 87.6 27.0 62.9 10.0 1.9 8.2 89.2 30.7 18.0 27.1 26.8 50.9 125.9 4.4 25.0 17.6 19.9 77.5 25.3 14.8 15.7 13.8 24.0 154.8 124.4 16.4 16.2 61.3 195.0 40.8 8.7 89.5 26.6 97.4 49.1 134.0 54.6 136.7 136.6 15.6 9.3 8.6 34.9 6.8 16.6 3.8 8.7 89.7 6.6 18.1 23.6 9.4 71.1 43.4 151.6 25.2 43.2 17.4 14.7 15.4 JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 3028.0;intestine: 7979.6;stomach 1: 5916.2" "Cell type enriched" "Detected in many" 16 "Plasma cells: 101294.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 121 "memory B-cell: 4173.0;naive B-cell: 2555.1;plasmacytoid DC: 3578.1" "Group enriched" "Detected in all" 137 "B-cells: 4173.0;dendritic cells: 3578.1" "Cell line enhanced" "Detected in many" "Daudi: 3953.8;Karpas-707: 2117.6;RPMI-8226: 4469.2;U-266/70: 8794.0;U-266/84: 3519.2;U-698: 4949.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" 130.2 76.6 0.7 1089.0 0.8 76.3 3028.0 0.4 3.0 205.2 3.1 7979.6 6145.8 94.2 25.0 654.4 115.0 492.4 45.6 0.4 1.4 43.3 116.8 620.2 1033.5 1.9 1.0 183.5 78.3 2.1 2.0 2.4 0.8 90.2 6426.5 0.3 2420.5 258.4 4.2 13.2 4277.1 200.3 7.0 819.4 5916.2 40.0 0.8 155.3 19.4 0.8 1746.7 1059.4 11.6 2.8 8.9 0.0 0.0 0.0 0.0 0.0 15.5 8.2 1.5 0.1 0.1 0.0 0.0 3953.8 3.3 12.7 0.1 6.6 0.0 0.0 0.6 2.1 0.0 3.3 0.0 0.0 0.0 3.3 9.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.4 2117.6 0.1 0.0 6.1 14.9 4.9 0.0 0.0 4.8 2.6 4469.2 0.0 0.0 3.3 15.7 3.7 2.6 2.7 0.0 0.8 6.8 3.9 9.9 11.8 4.9 6.3 8794.0 3519.2 4949.0 2.1 5.2 1.2 25.1 7.5 2.6 4.0 1.5 19.1 4173.0 2.5 3.8 6.6 2555.1 2.1 2.1 28.3 4.5 2.5 3578.1 2.6 1310.4 0.7 0.8 0.4 3.0 0.4 1.4 1.9 1.0 0.8 7.0 0.8 2.8 3.0 22.4 101.3 0.0 6154.9 0.0 28.2 0.0 8.6 0.0 11.7 1.9 2.2 15.7 8.1 0.0 0.0 0.1 700.0 5.1 0.0 0.0 0.5 0.0 0.1 38.1 7.3 139.0 0.0 0.0 0.1 48.8 228.8 0.0 79.5 0.1 66.4 24.6 0.3 0.0 0.0 5.3 0.0 35.8 0.0 0.3 0.0 42.0 0.0 0.0 3.9 0.0 6.2 0.0 0.0 0.0 5.1 0.0 101294.9 32.7 0.0 5.4 3.6 0.0 0.0 0.6 88.4 1.4 0.3 24.3 0.0 0.3 1487.8 0.0 3.5 0.6 JPH2 JP-2 ENSG00000149596 "Junctophilin 2" Q9BR39 20 44106590-44187188 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.2;skeletal muscle: 120.4" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 64.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 15.3;EFO-21: 15.0;fHDF/TERT166: 19.1;HeLa: 12.6;SiHa: 12.9" "Low region specificity" "Detected in some" HPA052646 Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA052646: AB_2681899" "unprognostic (1.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.61e-4)" "unprognostic (4.71e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.06e-2)" "unprognostic (2.45e-3)" "unprognostic (6.87e-2)" "unprognostic (9.16e-2)" "unprognostic (2.57e-2)" "unprognostic (9.73e-2)" "unprognostic (4.76e-2)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-2)" 6.0 1.9 0.5 4.5 0.6 0.1 5.7 0.4 0.7 15.1 0.7 63.3 2.1 51.6 2.9 11.9 30.0 3.5 85.2 0.4 0.5 1.4 0.3 5.2 0.2 1.1 1.1 3.9 0.3 0.1 1.2 3.8 0.8 23.8 4.5 0.2 5.8 22.1 120.4 3.8 11.8 27.5 0.9 1.3 16.0 0.8 0.6 0.1 1.5 48.3 0.1 40.5 10.6 0.7 7.5 0.8 0.4 0.0 0.3 0.4 1.5 2.2 4.1 5.4 2.3 15.3 5.9 0.0 15.0 19.1 6.1 10.5 0.0 0.5 2.1 0.0 0.0 0.0 12.6 0.1 0.1 0.3 0.0 0.7 1.1 2.7 3.7 3.3 0.0 0.0 0.0 0.0 7.3 4.3 0.0 0.2 0.3 0.0 0.9 1.7 3.4 0.0 0.4 0.1 0.0 0.1 12.9 3.1 0.1 8.6 10.8 0.1 0.3 2.4 2.7 0.5 4.7 0.1 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 0.7 0.4 0.5 1.1 1.1 0.8 0.9 0.6 0.7 0.2 0.0 0.0 0.3 0.0 6.6 0.5 0.9 0.0 0.0 0.4 5.1 64.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.8 0.0 0.5 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.2 0.0 6.6 15.9 12.8 0.0 1.5 0.0 2.0 0.5 0.1 0.0 0.2 0.1 JPT1 "ARM2, HN1, HN1A" ENSG00000189159 "Jupiter microtubule associated homolog 1" Q9UK76 17 75135248-75168281 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 406.9" "Cell type enhanced" "Detected in many" "Ductal cells: 371.3;Exocrine glandular cells: 437.2;Extravillous trophoblasts: 1344.2;monocytes: 375.7;Pancreatic endocrine cells: 1434.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 767.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059729 Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA 40000 "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA059729: AB_2684114" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-3)" "unprognostic (3.57e-3)" "unprognostic (6.71e-2)" "unprognostic (2.51e-3)" "prognostic unfavorable (1.58e-7)" "unprognostic (3.58e-2)" "unprognostic (1.37e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.25e-3)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.77e-7)" "unprognostic (1.83e-1)" "unprognostic (8.99e-2)" "unprognostic (4.84e-2)" "unprognostic (1.51e-1)" 26.1 74.9 44.0 87.5 43.7 83.5 21.3 49.4 54.7 44.1 31.0 140.1 119.2 18.0 7.3 225.1 15.5 63.7 23.3 44.3 54.4 72.2 49.1 49.3 87.6 38.6 42.8 13.4 22.6 6.7 24.3 66.3 49.3 28.3 70.4 17.0 62.1 27.8 96.1 40.7 141.6 23.4 34.3 100.5 134.2 406.9 53.1 88.0 16.1 24.3 91.5 93.9 75.7 36.3 775.3 743.0 371.8 384.7 75.5 75.2 309.5 391.8 111.5 364.6 278.0 614.8 449.1 210.1 247.4 303.0 401.7 446.5 344.3 481.9 278.5 215.7 438.3 336.1 275.2 624.8 177.5 256.3 318.3 117.1 218.4 307.3 308.7 107.1 672.2 388.7 197.3 431.3 335.4 561.4 845.0 248.7 216.9 627.8 979.0 520.8 447.5 326.8 392.7 479.1 465.4 373.8 553.8 293.3 213.4 393.8 786.0 154.9 395.1 214.3 615.7 305.0 469.0 165.9 298.1 332.5 186.9 233.4 254.4 241.7 127.0 372.6 79.6 187.8 57.2 102.3 109.3 96.8 100.7 57.2 51.6 76.1 767.6 74.5 206.7 67.4 202.6 118.4 44.0 43.7 49.4 54.7 44.3 54.4 38.6 42.8 49.3 34.3 53.1 36.3 61.6 25.6 18.1 0.0 36.2 0.0 0.0 0.0 0.0 0.0 81.8 133.2 0.0 0.0 18.0 246.5 0.0 137.6 171.2 0.0 99.7 371.3 0.0 113.2 79.7 32.9 0.0 0.0 0.0 437.2 1344.2 40.4 0.0 194.0 7.6 179.6 0.0 0.0 319.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.5 0.0 0.0 375.7 0.0 0.0 0.0 0.0 1434.1 0.0 0.0 13.9 0.0 0.0 203.3 16.8 0.0 0.0 0.0 76.2 0.0 0.0 0.0 0.0 96.9 73.9 95.0 0.0 0.0 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Growth regulation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016953, HPA074328" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Vesicles, Cytosol" "HPA016953: AB_1851277, HPA074328: " "unprognostic (2.20e-1)" "unprognostic (3.58e-1)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (7.16e-2)" "unprognostic (1.29e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-1)" "unprognostic (2.74e-1)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "prognostic favorable (1.10e-13)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.54e-2)" 31.6 30.0 38.7 23.8 41.0 52.9 32.1 41.7 48.8 39.5 38.6 43.6 21.6 45.1 33.7 34.9 44.9 20.5 32.4 37.9 38.9 32.9 26.3 29.5 28.0 40.0 39.5 39.2 32.7 45.6 33.7 29.9 41.2 33.1 27.0 31.0 29.6 36.3 42.8 47.6 32.2 35.2 40.0 34.3 35.9 45.2 39.9 39.3 38.2 34.6 30.2 39.5 34.8 43.8 37.2 44.1 40.1 29.6 31.3 32.7 41.1 26.7 43.6 44.0 38.0 32.6 42.2 34.3 36.2 47.4 47.5 30.8 50.8 45.1 26.4 44.4 32.5 50.6 36.3 38.9 44.6 55.7 56.4 35.2 49.7 28.9 59.0 33.7 28.1 39.1 52.5 51.1 42.0 68.2 45.7 62.3 33.9 26.8 28.4 38.2 26.5 63.3 40.6 56.2 37.1 38.9 25.4 46.5 51.2 20.8 45.9 34.2 36.3 33.9 30.4 27.6 28.0 38.7 43.7 50.4 29.7 27.0 29.3 42.7 33.6 58.8 33.4 32.0 29.6 28.2 28.8 34.2 34.1 30.4 36.5 29.8 34.8 35.8 34.6 20.9 31.0 36.4 38.7 41.0 41.7 48.8 37.9 38.9 40.0 39.5 41.2 40.0 39.9 43.8 17.6 12.8 17.5 10.7 26.0 21.2 44.2 60.2 17.6 44.9 17.3 15.0 1.0 25.8 33.8 29.5 31.3 51.3 25.6 27.1 35.2 42.2 11.1 20.2 14.2 18.7 30.4 12.4 7.5 51.5 42.6 21.1 20.4 19.8 33.7 27.0 18.2 10.9 36.3 38.7 8.7 25.1 42.7 17.6 15.2 11.1 28.0 20.4 42.7 3.7 38.8 40.3 33.0 7.1 13.8 39.4 30.6 38.7 10.4 24.2 23.3 32.6 30.0 44.8 46.0 27.6 27.0 61.1 27.8 14.6 21.3 102.5 21.6 29.2 26.2 31.0 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 14.4 7.1 8.6 15.4 12.7 38.2 12.3 20.1 10.5 13.7 9.7 10.2 9.6 15.6 8.6 13.4 12.0 11.2 9.1 9.1 12.8 9.1 10.0 16.7 16.8 12.7 12.4 21.5 11.7 18.0 6.7 14.9 12.9 11.0 10.6 18.1 9.6 9.7 13.1 16.6 12.1 13.5 8.2 15.7 11.3 11.4 10.1 27.0 14.2 16.0 17.2 12.0 10.7 16.7 19.6 23.2 34.8 21.8 17.8 20.3 9.8 15.4 20.6 17.9 14.2 16.3 11.5 33.4 13.4 19.0 19.5 17.3 27.3 18.6 23.2 16.1 14.4 60.4 14.2 10.3 14.8 27.3 23.6 17.1 19.1 20.4 24.8 14.5 18.8 29.7 36.6 24.2 16.0 10.4 59.9 9.4 12.8 20.4 8.1 37.7 39.1 9.9 11.0 27.1 17.6 16.7 15.8 12.4 13.8 15.8 26.3 12.9 25.5 21.6 15.3 21.1 15.5 16.8 22.1 33.8 12.6 14.1 17.3 2.5 0.8 1.8 1.6 0.9 1.6 1.4 1.6 2.1 0.6 1.6 1.9 1.8 5.1 1.9 0.9 1.1 1.9 1.2 8.6 12.7 20.1 10.5 9.1 12.8 12.7 12.4 12.9 8.2 10.1 16.7 87.5 35.3 34.9 64.0 54.0 50.3 24.2 15.5 18.2 54.8 31.7 25.5 23.7 18.6 25.3 12.9 54.2 14.4 61.5 23.2 3.9 14.2 2.6 30.3 47.5 56.7 24.7 31.2 62.8 11.8 17.0 32.4 21.4 44.8 35.4 31.9 43.5 25.3 17.0 58.9 76.6 24.9 10.2 44.2 34.5 4.8 28.3 43.7 23.2 120.9 30.3 27.9 61.8 93.5 129.2 15.7 20.2 23.0 38.7 30.7 22.9 10.6 22.8 44.9 19.7 49.3 34.6 37.8 37.0 23.0 61.2 21.1 61.4 19.7 19.3 27.2 KAT7 "HBO1, HBOA, MYST2, ZC2HC7" ENSG00000136504 "Lysine acetyltransferase 7" O95251 17 49788648-49835026 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, DNA replication, Transcription, Transcription regulation" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044470, HPA071116" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA044470: AB_10965785, HPA071116: " "unprognostic (1.30e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-3)" "unprognostic (2.20e-2)" "unprognostic (7.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (1.36e-1)" "unprognostic (6.26e-2)" "unprognostic (1.44e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-3)" "unprognostic (2.75e-1)" "unprognostic (5.03e-2)" "unprognostic (6.23e-2)" "unprognostic (7.68e-2)" 17.6 14.2 16.1 8.1 16.9 40.9 16.6 24.2 21.5 20.1 15.1 20.9 7.2 22.6 12.2 20.4 20.3 6.6 22.8 16.5 14.8 17.7 11.7 14.5 10.4 13.6 12.3 20.9 12.4 23.5 17.1 10.0 15.5 17.5 10.0 19.2 17.8 14.0 37.7 25.5 16.0 12.4 10.3 15.9 16.0 38.6 14.9 17.4 21.1 20.1 13.5 22.5 19.0 18.7 17.1 22.6 22.5 17.3 10.1 14.3 27.2 11.2 16.5 24.7 18.7 35.9 11.5 17.8 21.8 13.7 24.7 16.7 23.0 12.8 32.5 18.6 20.3 20.7 14.8 17.8 15.0 21.6 17.2 13.3 16.6 21.1 25.3 14.4 22.7 16.0 23.6 18.9 27.4 28.8 26.4 23.2 79.0 38.4 20.2 20.6 34.7 18.2 12.8 17.6 25.7 15.7 7.6 9.2 14.9 40.5 38.6 22.9 8.8 24.5 13.3 16.0 19.4 21.4 32.7 23.3 17.3 13.6 23.3 17.1 6.8 9.5 8.3 5.4 10.6 5.8 7.8 8.5 7.0 6.1 9.3 8.5 10.1 11.7 7.1 4.3 8.5 7.9 16.1 16.9 24.2 21.5 16.5 14.8 13.6 12.3 15.5 10.3 14.9 18.7 16.0 25.6 21.3 9.4 23.6 16.8 11.7 10.1 25.0 32.6 18.5 16.6 28.5 20.0 15.6 27.6 31.3 22.7 27.6 11.7 9.8 11.9 23.1 22.4 21.0 18.7 25.1 25.4 14.8 7.5 14.5 15.3 15.3 29.9 24.1 18.2 15.4 10.4 13.3 45.4 16.7 13.4 12.2 22.6 13.2 16.5 16.8 15.9 14.2 10.3 19.1 16.5 25.7 13.0 18.3 10.0 8.9 18.4 18.6 15.4 12.8 10.2 18.6 25.1 39.5 21.2 24.2 73.7 31.6 17.9 20.0 33.8 28.4 15.2 12.1 10.2 KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061989-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 23.0;Gastric mucus-secreting cells: 44.4;Intestinal goblet cells: 53.5;Proximal enterocytes: 78.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 30.8;T-47d: 36.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011800 Uncertain "Secreted to extracellular matrix" NA NA 65000 "Cluster 64: Macrophages - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA011800: AB_1852082" "unprognostic (3.34e-1)" "unprognostic (8.86e-3)" "unprognostic (1.16e-2)" "unprognostic (4.43e-3)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (3.44e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.11e-1)" 2.9 0.6 0.3 0.6 0.2 0.3 2.8 0.3 0.4 7.1 0.1 1.9 2.8 2.0 1.3 0.6 2.1 0.6 8.1 0.5 0.2 2.0 0.5 1.2 0.7 0.4 0.3 0.5 0.9 0.8 3.6 0.8 0.4 5.2 1.6 0.4 6.9 2.2 4.1 1.7 3.2 1.5 0.2 18.0 6.6 1.9 0.4 1.0 2.5 3.1 0.3 3.6 2.9 0.2 3.3 1.6 1.8 30.8 1.8 7.4 2.0 5.2 5.6 1.0 1.0 6.2 2.0 0.2 2.8 4.6 0.5 0.7 1.9 0.1 0.3 3.1 0.8 0.4 6.5 6.7 0.5 0.4 2.3 1.1 0.4 0.1 0.9 0.4 0.0 0.9 0.7 3.2 0.9 5.3 0.1 1.9 0.5 7.2 11.7 12.4 9.1 0.4 0.6 1.6 0.3 1.2 0.5 0.8 1.7 0.7 36.7 0.5 0.1 0.7 2.1 0.5 1.2 0.9 2.6 2.5 1.3 3.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.4 0.5 0.2 0.4 0.3 0.4 0.2 0.4 0.2 8.3 0.0 1.5 0.7 0.3 2.0 0.9 1.6 0.6 1.5 2.5 3.0 3.4 1.5 1.6 0.0 2.1 0.3 0.3 23.0 1.9 0.5 0.1 4.1 1.3 5.1 2.4 2.7 0.1 2.1 0.6 16.9 44.4 7.2 0.0 0.2 3.6 0.3 0.8 0.0 0.1 53.5 4.1 4.8 1.9 0.1 9.9 0.9 1.8 0.0 0.0 0.8 0.0 0.0 0.1 1.5 12.8 0.4 0.2 5.0 78.1 0.4 0.7 2.2 0.0 10.4 6.1 3.9 1.4 0.7 2.8 0.5 0.6 0.2 8.1 0.4 KCNA3 "HLK3, HPCN3, Kv1.3, MK3" ENSG00000177272 "Potassium voltage-gated channel subfamily A member 3" P22001 1 110672465-110674940 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 25.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 13.1;Inhibitory neurons: 60.2;Plasma cells: 61.6;T-cells: 20.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 4.9;T-cells: 14.3" "Cell line enhanced" "Detected in some" "HDLM-2: 23.1;Karpas-707: 45.6;U-266/70: 32.6;U-266/84: 31.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016625 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "HPA016625: AB_2669407" "unprognostic (2.17e-2)" "unprognostic (5.07e-3)" "unprognostic (3.92e-3)" "unprognostic (1.20e-2)" "unprognostic (2.35e-1)" "unprognostic (1.76e-5)" "unprognostic (1.70e-4)" "unprognostic (8.48e-2)" "unprognostic (1.49e-2)" "unprognostic (5.92e-4)" "unprognostic (1.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.13e-2)" "unprognostic (2.99e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" 0.5 0.9 3.4 6.4 2.0 4.6 0.9 1.1 4.9 1.1 0.0 2.4 2.5 0.5 0.0 0.5 0.3 1.3 0.4 5.0 7.2 0.2 0.8 5.9 9.4 1.1 3.3 0.7 0.4 0.4 0.4 0.7 5.0 0.5 1.9 0.6 1.4 0.2 0.1 0.2 2.6 0.6 0.2 6.0 4.3 0.5 3.3 25.4 0.7 0.1 7.6 2.6 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 45.6 0.0 0.0 10.0 0.0 0.9 0.0 0.0 0.0 0.0 9.6 0.0 0.0 6.3 0.5 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.7 0.0 0.0 32.6 31.9 11.6 0.0 2.7 0.0 0.0 1.1 0.0 8.9 0.0 10.0 2.8 13.4 14.3 1.4 4.9 10.4 7.9 0.0 1.3 0.1 0.6 13.4 4.4 3.4 2.0 1.1 4.9 5.0 7.2 1.1 3.3 5.0 0.2 3.3 0.0 0.2 0.0 1.9 1.3 11.5 0.4 0.0 0.0 0.0 2.5 0.1 0.0 0.6 0.0 0.0 1.8 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.3 13.1 0.0 0.0 0.7 1.5 0.0 0.0 0.0 1.8 0.0 0.4 0.0 60.2 0.0 0.0 1.6 2.4 0.0 0.0 3.1 3.6 2.8 2.4 0.3 3.1 7.5 1.3 0.0 0.0 0.0 61.6 0.0 0.0 0.1 0.0 0.2 6.6 0.0 0.1 4.3 0.9 0.1 0.6 0.0 20.3 0.0 0.0 0.1 KCNH1 "eag, eag1, h-eag, hEAG, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134165 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 533.5;Inhibitory neurons: 261.0;Oligodendrocytes: 116.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 6.2;RH-30: 10.1;RPTEC TERT1: 6.0;SH-SY5Y: 12.9;SK-MEL-30: 12.9;T-47d: 9.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 34.0;cerebellum: 19.1;cerebral cortex: 23.9;hippocampal formation: 17.9;olfactory bulb: 8.9" "HPA014551, HPA019445, HPA076421" Enhanced Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA014551: AB_2669038, HPA019445: AB_1852118, HPA076421: " "unprognostic (9.12e-2)" "unprognostic (4.82e-3)" "unprognostic (2.63e-1)" "unprognostic (6.70e-2)" "unprognostic (3.56e-1)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (9.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.77e-2)" "unprognostic (1.42e-3)" "unprognostic (1.17e-1)" "unprognostic (8.89e-2)" "unprognostic (1.36e-1)" "unprognostic (9.70e-2)" 0.2 0.9 6.8 0.4 9.2 0.0 0.2 9.5 17.9 0.7 2.7 0.5 0.3 0.4 0.2 0.1 0.6 0.2 0.0 11.2 5.3 0.1 0.1 0.0 0.0 4.8 4.4 0.1 0.2 0.0 0.7 0.3 4.0 0.5 0.3 0.3 0.1 0.1 0.2 0.1 0.8 0.2 4.0 0.0 0.5 1.5 4.9 0.2 0.1 0.6 0.0 0.2 0.4 8.3 0.0 2.1 0.4 0.1 0.0 0.1 0.1 1.0 0.2 2.1 2.4 0.0 0.0 0.0 0.0 1.4 2.4 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 10.1 0.0 6.0 0.0 0.4 12.9 2.4 0.2 12.9 1.7 9.2 0.0 0.0 1.6 0.2 2.0 1.2 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 9.2 9.5 17.9 11.2 5.3 4.8 4.4 4.0 4.0 4.9 8.3 0.2 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 11.2 0.2 2.8 0.1 0.0 0.0 533.5 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 261.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 7.5 0.0 0.0 0.0 19.1 116.6 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNH2 "erg1, HERG, Kv11.1, LQT2" ENSG00000055118 "Potassium voltage-gated channel subfamily H member 2" Q12809 7 150944961-150978321 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.3;pituitary gland: 43.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 217.3;Cardiomyocytes: 83.2;Erythroid cells: 76.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "K-562: 197.7;NB-4: 97.8;SH-SY5Y: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (2.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (6.06e-5)" "unprognostic (9.79e-3)" "unprognostic (1.95e-2)" "unprognostic (3.40e-2)" "unprognostic (3.84e-2)" "unprognostic (3.53e-2)" "unprognostic (3.52e-1)" "prognostic favorable (5.61e-4)" "unprognostic (6.08e-2)" "unprognostic (2.26e-2)" "unprognostic (4.90e-2)" "unprognostic (2.83e-1)" "unprognostic (6.24e-2)" "unprognostic (3.02e-2)" 0.8 3.7 9.8 2.6 8.0 42.3 0.1 13.5 9.0 4.4 4.4 36.1 2.7 16.9 1.7 1.5 7.3 3.2 29.6 5.6 14.8 1.1 0.2 2.0 0.3 23.5 14.7 3.2 3.4 18.1 43.3 1.4 23.0 9.8 1.0 6.7 1.1 8.0 0.2 0.3 8.3 7.8 6.3 1.8 10.9 30.8 17.1 0.4 0.2 0.0 0.1 12.9 2.7 4.1 0.0 0.3 0.9 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 8.0 2.9 0.0 0.2 0.0 3.1 0.0 0.0 0.8 0.4 18.3 0.0 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 4.4 197.7 0.0 0.0 0.9 1.6 97.8 1.3 0.2 0.0 0.1 0.1 10.1 0.0 0.0 3.8 78.2 0.0 0.1 0.0 1.1 0.0 1.8 0.6 0.0 1.5 0.0 0.0 5.3 0.2 2.1 0.0 11.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 8.0 13.5 9.0 5.6 14.8 23.5 14.7 23.0 6.3 17.1 4.1 0.0 0.0 0.0 1.6 1.6 0.0 0.2 0.1 0.0 217.3 0.4 0.3 83.2 0.0 0.0 0.0 4.2 0.2 0.0 0.0 0.0 2.1 2.0 0.5 0.8 0.9 16.3 76.4 5.2 0.2 0.9 5.0 0.5 0.1 26.1 6.3 1.4 0.1 0.3 16.8 13.9 0.7 12.2 0.0 0.3 4.8 2.5 0.0 0.0 2.8 0.0 4.5 0.0 5.5 1.7 0.3 0.0 13.2 1.4 0.1 0.2 0.1 0.4 10.3 0.0 1.7 2.6 2.5 5.1 0.0 0.0 0.3 0.9 0.7 0.3 0.4 KCNH8 "elk3, Kv12.1" ENSG00000183960 "Potassium voltage-gated channel subfamily H member 8" Q96L42 3 19148510-19535642 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.0;pituitary gland: 10.7" "Group enriched" "Detected in some" 63 "Oligodendrocyte precursor cells: 331.7;Oligodendrocytes: 989.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.4" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cell line enhanced" "Detected in some" "HAP1: 1.0;OE19: 1.9;SH-SY5Y: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA016586, HPA077537, HPA077773" Approved Supported "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA016586: AB_1852127, HPA077537: , HPA077773: " "unprognostic (6.68e-3)" "unprognostic (1.68e-1)" "unprognostic (2.99e-2)" "unprognostic (8.56e-6)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.88e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (1.69e-1)" "unprognostic (5.04e-3)" "unprognostic (2.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (3.89e-2)" "unprognostic (8.71e-5)" "unprognostic (1.72e-1)" 0.0 1.8 7.3 0.3 11.9 0.2 0.5 6.5 16.0 0.3 2.8 0.6 0.4 0.1 0.1 0.1 0.2 0.4 0.2 6.4 8.8 0.1 0.1 0.0 0.8 8.4 8.8 0.0 1.5 0.1 10.7 0.0 8.2 0.7 0.5 3.4 1.1 0.2 0.0 0.4 1.1 0.1 5.8 1.1 1.4 1.7 9.7 0.4 0.2 0.0 0.7 0.1 0.3 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 7.3 11.9 6.5 16.0 6.4 8.8 8.4 8.8 8.2 5.8 9.7 15.4 0.0 0.0 0.0 2.0 9.7 0.5 1.6 0.0 0.0 4.2 1.1 2.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 3.2 0.1 0.1 0.1 3.6 0.0 9.3 0.6 0.0 0.1 2.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 10.4 1.5 0.0 0.0 0.0 1.9 0.0 0.1 3.6 1.0 0.0 3.4 0.0 331.7 989.4 0.5 0.2 0.0 0.1 1.5 0.0 0.0 0.0 1.0 0.0 0.2 0.5 1.2 3.4 0.0 0.0 0.1 0.3 0.1 0.6 0.4 KCNIP1 KCHIP1 ENSG00000182132 "Potassium voltage-gated channel interacting protein 1" Q9NZI2 5 170353487-170736632 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7;choroid plexus: 15.1;epididymis: 21.6" "Cell type enhanced" "Detected in some" "Astrocytes: 57.8;Horizontal cells: 50.5;Inhibitory neurons: 221.4;Microglial cells: 167.7;Oligodendrocyte precursor cells: 196.1" "Cancer enriched" "Detected in some" 18 "glioma: 22.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "RPTEC TERT1: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022864, HPA066717" Uncertain Approved Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA022864: AB_1858712, HPA066717: " "unprognostic (7.75e-5)" "unprognostic (2.66e-2)" "unprognostic (6.78e-2)" "unprognostic (3.22e-4)" "unprognostic (4.51e-2)" "unprognostic (3.49e-1)" "unprognostic (1.25e-2)" "unprognostic (2.69e-1)" "unprognostic (5.46e-2)" "unprognostic (6.62e-3)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.55e-1)" "unprognostic (2.58e-2)" "unprognostic (1.63e-1)" "unprognostic (2.39e-1)" "unprognostic (6.05e-2)" 0.5 4.2 23.5 0.5 26.5 0.0 1.0 19.4 28.3 2.7 15.1 0.7 0.2 1.6 21.6 0.3 1.7 1.8 0.4 21.8 32.6 3.8 0.1 1.0 0.5 24.3 26.6 0.3 1.4 1.3 1.0 1.2 24.7 1.5 0.5 5.8 0.4 5.6 0.1 0.4 0.3 1.1 28.7 1.5 0.4 2.7 32.7 0.1 0.7 0.2 0.4 0.5 0.6 19.6 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 58.7 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 26.5 19.4 28.3 21.8 32.6 24.3 26.6 24.7 28.7 32.7 19.6 0.0 0.0 0.0 57.8 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 2.0 1.2 0.0 0.0 18.6 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 50.5 221.4 0.0 0.0 0.0 0.6 0.7 5.0 0.1 0.0 167.7 0.0 0.2 0.0 196.1 2.8 0.0 0.0 11.7 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 KCNIP2 KCHIP2 ENSG00000120049 "Potassium voltage-gated channel interacting protein 2" Q9NS61 10 101825974-101843920 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 227.4;brain: 139.6;heart muscle: 307.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 54.3;Cardiomyocytes: 135.7;Cone photoreceptor cells: 25.0;Excitatory neurons: 23.3;Horizontal cells: 48.8;Inhibitory neurons: 41.9" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 21.3;HMC-1: 12.7" "Group enriched" "Detected in all" 4 "amygdala: 96.8;basal ganglia: 234.9;cerebral cortex: 106.9;hippocampal formation: 142.6;olfactory bulb: 144.0" "Low region specificity" "Detected in all" HPA066717 Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA066717: " "unprognostic (5.92e-2)" "unprognostic (2.16e-1)" "unprognostic (3.48e-3)" "unprognostic (5.77e-4)" "unprognostic (1.34e-1)" "unprognostic (1.31e-3)" "unprognostic (8.80e-2)" "unprognostic (9.11e-3)" "unprognostic (1.14e-1)" "unprognostic (5.34e-2)" "unprognostic (3.18e-2)" "unprognostic (7.20e-2)" "unprognostic (1.49e-9)" "unprognostic (9.85e-2)" "unprognostic (1.81e-1)" "unprognostic (3.27e-1)" "unprognostic (8.37e-4)" 227.4 6.8 74.5 3.5 139.6 0.9 67.1 48.8 84.5 7.4 40.5 5.0 1.8 4.1 4.1 2.5 4.9 3.1 307.5 98.8 50.6 2.8 2.3 2.5 8.1 47.5 51.6 11.5 2.4 1.7 19.7 2.9 48.1 5.2 4.7 52.6 9.9 3.5 8.0 5.9 5.3 2.6 50.3 5.7 2.7 8.5 57.1 2.3 3.5 5.4 8.3 4.8 4.4 60.8 1.7 2.6 2.5 3.2 1.0 1.1 0.6 1.2 1.0 0.6 0.9 3.6 3.4 1.6 0.9 0.8 0.7 1.7 0.9 0.4 0.6 2.4 2.0 21.3 3.0 1.9 0.9 1.4 12.7 2.6 1.7 1.0 1.4 3.7 1.0 4.7 6.3 1.8 1.0 1.2 0.8 4.0 0.8 0.7 0.6 1.0 0.2 1.4 1.0 1.1 7.4 1.2 0.8 0.6 2.4 1.5 2.2 0.9 2.3 1.3 2.0 0.6 1.2 1.7 1.9 1.7 1.4 5.3 0.2 0.0 0.0 0.7 0.0 0.5 0.1 0.9 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 74.5 139.6 48.8 84.5 98.8 50.6 47.5 51.6 48.1 50.3 57.1 60.8 0.4 0.0 0.0 8.5 2.3 0.4 0.1 0.3 0.0 54.3 0.3 0.5 135.7 0.0 0.1 1.8 25.0 0.2 0.0 0.8 0.0 0.2 6.6 0.0 0.2 1.6 0.0 0.0 23.3 0.0 0.2 5.8 0.0 0.0 0.0 0.8 0.4 0.1 2.2 48.8 41.9 0.4 0.0 0.6 0.8 5.2 1.8 0.3 0.0 1.0 0.5 8.3 0.0 5.5 3.7 0.3 0.2 0.7 0.3 0.1 0.5 0.1 0.2 4.7 0.0 0.1 1.3 2.5 5.5 0.5 0.0 0.3 0.1 0.5 0.3 0.1 KCNJ5 "CIR, GIRK4, KATP1, Kir3.4, LQT13" ENSG00000120457 "Potassium inwardly rectifying channel subfamily J member 5" P48544 11 128891356-128921163 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 64.3;pancreas: 20.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 48.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "HBEC3-KT: 13.3" "Group enriched" "Detected in many" 6 "basal ganglia: 2.9;hypothalamus: 6.8;midbrain: 1.9;thalamus: 3.6" "Low region specificity" "Detected in all" "HPA014722, HPA017353, CAB022569" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "CAB022569: , HPA014722: AB_1852133, HPA017353: AB_1852135" "unprognostic (2.01e-1)" "unprognostic (2.43e-3)" "unprognostic (2.56e-3)" "unprognostic (5.81e-2)" "unprognostic (4.24e-2)" "unprognostic (3.60e-2)" "unprognostic (2.90e-1)" "unprognostic (3.54e-2)" "unprognostic (6.83e-2)" "unprognostic (1.96e-1)" "unprognostic (3.17e-1)" "unprognostic (9.29e-2)" "unprognostic (1.81e-2)" "unprognostic (6.82e-2)" "unprognostic (9.49e-2)" "unprognostic (1.88e-2)" "unprognostic (2.23e-2)" 1.5 64.3 1.2 0.6 0.9 0.4 0.9 0.6 2.0 1.3 0.2 0.8 0.8 0.3 0.9 1.0 0.9 2.2 8.5 0.7 3.2 5.4 0.4 5.9 1.6 3.7 1.7 0.9 20.4 1.3 11.9 7.3 2.7 1.3 0.7 1.0 0.9 9.6 0.4 0.4 0.5 0.6 1.7 13.6 2.3 1.1 7.9 5.8 0.5 0.4 0.5 1.5 0.4 3.9 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.3 13.3 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 1.2 0.9 0.6 2.0 0.7 3.2 3.7 1.7 2.7 1.7 7.9 3.9 0.2 0.0 10.0 0.3 0.2 1.5 2.2 4.7 0.0 2.7 0.2 1.4 7.6 0.0 0.3 1.8 0.0 0.8 0.1 0.0 0.0 0.1 2.3 0.2 0.2 0.6 0.0 0.0 0.2 3.9 0.7 1.1 0.0 0.3 0.0 0.2 0.4 0.1 48.3 1.7 3.1 0.0 0.0 2.2 2.9 7.8 0.9 10.9 3.6 3.7 1.2 0.3 3.1 0.5 0.1 0.8 0.0 0.7 0.3 0.6 0.0 0.1 0.3 1.4 0.0 0.9 0.2 0.9 0.5 0.5 1.7 1.2 0.6 2.3 0.0 0.6 KCNJ8 Kir6.1 ENSG00000121361 "Potassium inwardly rectifying channel subfamily J member 8" Q15842 12 21764955-21775600 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 71.3" "Group enriched" "Detected in many" 4 "Sertoli cells: 197.2;Smooth muscle cells: 61.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Cell line enhanced" "Detected in some" "BJ: 11.1;CACO-2: 58.4;SH-SY5Y: 30.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031066 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA031066: AB_10602240" "unprognostic (8.12e-3)" "unprognostic (1.89e-1)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.81e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-2)" "unprognostic (3.90e-2)" "unprognostic (3.66e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (1.62e-6)" "unprognostic (4.70e-3)" "unprognostic (9.61e-2)" "unprognostic (1.73e-2)" "unprognostic (3.54e-3)" 28.6 17.3 4.9 3.2 5.4 0.0 22.1 4.8 5.7 17.0 11.6 15.6 1.2 18.8 0.7 3.6 14.8 1.8 71.3 4.7 5.0 13.9 41.9 13.8 2.5 5.2 5.3 16.8 42.4 1.8 7.8 3.0 5.1 13.0 0.3 0.8 6.4 8.4 17.1 5.8 5.9 5.5 5.2 8.0 12.7 1.0 7.2 0.6 16.1 4.5 0.4 15.1 11.5 4.7 0.0 0.1 0.9 0.0 1.4 3.2 0.0 11.1 4.4 6.5 1.9 58.4 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.1 0.0 4.3 2.9 0.0 0.0 0.0 0.0 0.0 4.5 0.0 3.2 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.0 5.0 0.0 0.0 0.0 6.6 2.7 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.4 4.8 5.7 4.7 5.0 5.2 5.3 5.1 5.2 7.2 4.7 18.7 3.2 29.5 2.9 0.0 1.3 0.4 0.0 0.6 0.0 9.2 3.0 28.3 0.0 0.6 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.7 10.8 12.8 1.2 0.0 3.6 1.3 0.0 9.8 0.0 0.9 0.0 1.0 2.9 23.0 0.3 0.0 0.2 0.0 0.0 0.8 1.5 0.1 0.3 0.3 1.8 0.0 0.0 13.2 0.0 0.5 0.4 1.2 0.0 0.7 0.1 0.4 0.0 0.0 0.0 2.0 197.2 3.3 61.6 0.0 1.0 0.1 0.9 0.3 0.3 0.5 0.2 0.6 KCNK1 "DPK, K2p1.1, TWIK-1" ENSG00000135750 "Potassium two pore domain channel subfamily K member 1" O00180 1 233614106-233672514 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 157.8;Horizontal cells: 200.2;Prostatic glandular cells: 222.9;Urothelial cells: 371.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 69 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 69 "dendritic cells: 6.9" "Cell line enhanced" "Detected in many" "HeLa: 64.7;SCLC-21H: 62.5;U-266/70: 137.3;U-266/84: 134.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 117.0" "HPA016049, CAB022588" Approved Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB022588: , HPA016049: AB_1855571" "unprognostic (7.06e-3)" "unprognostic (1.76e-1)" "unprognostic (4.64e-2)" "unprognostic (7.46e-2)" "unprognostic (9.15e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.84e-4)" "unprognostic (4.32e-2)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (7.29e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" 3.9 4.1 17.7 2.9 19.8 0.3 5.7 58.0 28.4 7.8 50.4 15.7 16.9 6.1 30.9 20.9 10.9 12.1 41.0 24.3 13.7 9.2 12.1 4.4 1.0 23.5 17.8 7.3 5.5 16.2 22.2 6.8 24.1 6.4 13.9 18.5 15.1 11.3 0.4 13.3 12.6 3.8 15.4 0.9 38.1 0.9 16.3 0.5 7.2 0.9 4.4 11.5 14.4 21.3 33.2 18.3 0.1 0.0 0.0 0.0 50.2 8.8 0.0 0.0 0.0 0.0 52.9 0.0 20.7 6.8 7.3 47.1 8.9 15.2 0.0 0.1 15.8 0.0 64.7 0.0 0.5 0.0 1.8 3.9 17.0 0.0 12.4 1.1 0.2 17.7 7.9 15.0 0.0 12.6 12.2 0.1 10.9 38.5 41.0 0.0 2.7 3.7 16.0 28.4 62.5 11.8 33.5 14.3 0.0 1.0 4.1 0.1 0.0 0.1 25.8 0.0 1.0 137.3 134.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 17.7 19.8 58.0 28.4 24.3 13.7 23.5 17.8 24.1 15.4 16.3 21.3 0.4 9.6 22.9 5.9 0.6 63.3 136.7 32.6 3.4 2.9 23.0 6.0 54.7 12.8 44.6 18.4 4.2 0.5 3.0 91.0 1.9 29.2 1.1 52.7 26.4 3.5 29.3 0.0 157.8 48.3 14.0 31.2 50.4 89.3 0.0 15.0 0.0 8.9 0.6 200.2 61.0 56.3 24.4 0.3 4.4 0.2 1.5 1.0 10.6 12.2 0.0 72.6 0.0 36.2 73.2 96.3 82.4 0.0 0.2 222.9 10.6 8.8 42.9 5.1 0.0 2.3 6.9 0.6 3.2 19.1 47.6 0.8 1.4 0.5 31.2 371.6 KCNK10 "K2p10.1, PPP1R97, TREK-2, TREK2" ENSG00000100433 "Potassium two pore domain channel subfamily K member 10" P57789 14 88180103-88326907 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;intestine: 5.1;stomach 1: 2.6" "Group enriched" "Detected in some" 4 "dendritic cells: 12.5;Excitatory neurons: 43.8;Inhibitory neurons: 17.0;Oligodendrocyte precursor cells: 37.7;Oligodendrocytes: 11.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 62 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in single" 100 "dendritic cells: 10.0" "Cell line enhanced" "Detected in some" "OE19: 1.5;REH: 1.7;SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030462 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA030462: AB_10601919" "unprognostic (9.52e-3)" "unprognostic (1.17e-1)" "unprognostic (1.94e-2)" "unprognostic (1.08e-1)" "unprognostic (8.20e-2)" "unprognostic (1.45e-1)" "unprognostic (1.18e-1)" "unprognostic (2.25e-1)" "unprognostic (4.58e-1)" "unprognostic (1.23e-2)" "unprognostic (2.70e-1)" "unprognostic (2.45e-1)" "unprognostic (6.97e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-1)" "unprognostic (4.26e-3)" 0.0 0.3 4.0 0.4 3.6 0.2 0.0 5.1 4.1 0.2 0.0 1.3 5.1 0.0 0.0 1.1 0.0 0.0 0.0 4.4 2.9 2.4 0.0 0.1 0.1 4.2 2.9 0.0 1.4 0.0 0.5 0.0 3.5 0.0 0.7 0.1 0.2 0.0 0.0 0.0 2.6 0.1 2.3 0.1 2.6 0.5 2.4 0.0 0.0 0.0 0.4 0.0 0.2 4.6 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.1 1.7 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.1 4.0 3.6 5.1 4.1 4.4 2.9 4.2 2.9 3.5 2.3 2.4 4.6 0.0 0.0 0.0 0.7 0.1 0.6 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 12.5 2.1 0.0 0.0 0.7 0.0 0.0 0.1 1.8 0.0 43.8 0.6 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.0 1.6 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 37.7 11.9 0.1 0.3 0.0 0.0 0.0 1.5 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 3.2 0.0 0.0 0.1 0.0 1.6 0.1 KCNK5 "K2p5.1, TASK-2, TASK2" ENSG00000164626 "Potassium two pore domain channel subfamily K member 5" O95279 6 39188971-39229475 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.4;kidney: 37.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 48.6;Distal enterocytes: 55.6;Gastric mucus-secreting cells: 31.6;Proximal enterocytes: 66.5;Proximal tubular cells: 45.4;Syncytiotrophoblasts: 45.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 34.9;HEL: 36.1;HMC-1: 31.8;K-562: 34.3;OE19: 27.4;T-47d: 25.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059148 Uncertain Approved Nucleoplasm NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA059148: AB_2683929" "unprognostic (1.46e-1)" "prognostic favorable (3.29e-4)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (8.09e-4)" "unprognostic (3.97e-2)" "unprognostic (2.33e-1)" "unprognostic (9.57e-3)" "unprognostic (7.14e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (2.98e-1)" "prognostic favorable (4.98e-7)" "unprognostic (2.34e-1)" "unprognostic (7.13e-2)" "unprognostic (1.03e-2)" "prognostic favorable (4.45e-4)" 4.0 3.7 0.1 2.2 0.1 9.6 5.3 0.0 0.1 4.4 0.1 14.2 28.4 2.1 0.2 6.1 2.3 18.8 1.7 0.0 0.2 37.2 23.5 6.1 2.7 0.2 0.2 6.4 20.4 1.9 1.2 8.6 0.1 3.5 8.5 0.1 27.1 2.4 0.2 29.4 35.4 1.3 0.1 2.2 16.7 0.7 0.3 1.8 10.0 0.1 1.9 3.2 6.7 0.0 6.6 5.9 7.7 2.9 0.0 0.0 6.6 0.0 0.0 0.0 0.0 34.9 14.3 0.0 10.2 0.0 0.8 13.2 6.0 0.2 0.0 0.0 4.5 36.1 3.1 0.2 0.0 7.5 31.8 0.0 0.1 0.2 0.0 0.0 0.0 7.8 34.3 0.1 0.0 11.4 16.7 8.1 14.4 27.4 0.0 0.0 1.4 13.6 5.3 5.4 1.9 1.5 5.7 7.3 0.0 2.9 25.9 12.1 0.2 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.1 0.3 0.0 2.3 0.0 19.2 0.0 0.1 3.7 2.5 1.5 5.7 0.0 4.2 3.2 0.6 48.6 7.7 1.8 0.0 28.8 0.8 55.6 5.9 14.5 0.1 2.6 0.3 6.9 0.0 6.1 0.0 11.8 5.3 3.2 31.6 5.3 0.0 2.2 0.0 27.5 2.1 0.0 0.0 15.3 8.2 0.6 3.5 0.7 0.6 0.8 1.8 0.0 0.6 0.0 0.0 0.0 0.0 12.1 25.1 0.0 0.4 2.6 66.5 45.4 1.0 0.0 0.0 2.4 0.6 0.0 1.1 8.2 2.7 45.6 3.5 1.4 11.1 10.4 KCNK7 K2p7.1 ENSG00000173338 "Potassium two pore domain channel subfamily K member 7" Q9Y2U2 11 65592836-65595996 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 90.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 103.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 2.1;naive B-cell: 2.2;neutrophil: 1.5" "Group enriched" "Detected in many" 16 "B-cells: 2.2;granulocytes: 2.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA077577 Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA077577: AB_2686845" "unprognostic (1.12e-2)" "unprognostic (1.21e-1)" "unprognostic (6.08e-2)" "unprognostic (5.71e-2)" "unprognostic (8.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "unprognostic (6.90e-2)" "unprognostic (4.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.65e-1)" "unprognostic (3.57e-1)" "unprognostic (1.16e-1)" "unprognostic (8.11e-2)" 2.0 0.7 2.7 0.2 2.9 5.4 2.9 3.4 5.7 4.6 1.7 2.1 0.4 1.4 0.1 18.0 2.3 0.3 1.6 2.7 2.4 0.7 0.9 1.7 0.3 2.8 2.8 1.8 0.4 0.0 1.3 0.4 3.0 1.4 0.0 0.7 2.5 0.3 2.6 90.0 1.2 0.2 2.7 2.0 1.2 1.1 2.7 0.4 0.6 0.5 1.0 1.7 9.5 3.4 0.3 1.6 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.1 1.0 0.4 0.4 0.1 0.2 2.2 0.0 0.0 0.0 0.5 1.1 0.5 0.9 0.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.6 1.3 0.4 1.0 0.5 0.4 0.6 0.6 0.6 0.9 0.0 0.2 0.6 0.1 6.8 1.5 0.3 0.4 0.7 0.0 0.4 1.1 0.0 0.3 1.1 1.0 0.1 0.9 0.7 0.2 0.5 0.6 0.6 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 2.7 2.9 3.4 5.7 2.7 2.4 2.8 2.8 3.0 2.7 2.7 3.4 1.1 0.0 0.5 0.3 0.8 19.1 0.4 0.7 0.6 2.1 0.7 1.8 0.2 0.0 0.7 0.0 0.0 0.1 1.6 1.0 0.0 0.1 0.7 0.7 0.3 1.2 1.2 0.0 0.9 0.0 0.1 0.4 0.0 1.7 0.0 0.2 0.7 0.3 0.5 0.0 0.9 0.4 0.0 1.3 4.0 1.8 0.6 0.7 3.6 0.0 0.4 0.1 0.0 1.0 1.8 0.1 4.8 0.0 0.0 0.3 0.3 0.1 1.1 1.1 6.6 0.4 0.8 0.1 1.3 16.3 103.7 0.0 0.6 0.1 0.8 1.3 KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43781257 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 130.8" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 231.1;Syncytiotrophoblasts: 763.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.7;WM-115: 258.6" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" 3.6 0.7 1.7 11.8 1.9 18.3 12.4 1.3 1.8 11.8 1.4 18.5 6.4 1.6 1.8 6.5 5.8 3.5 1.1 1.5 1.6 1.4 0.8 7.3 12.5 1.6 1.6 0.6 1.0 0.0 0.7 14.3 1.7 28.6 6.2 0.2 130.8 7.5 0.4 29.1 26.0 0.7 1.9 20.5 35.1 2.7 2.0 5.0 2.1 0.2 9.2 18.2 6.5 2.3 22.4 35.2 0.1 0.2 0.0 2.2 55.0 0.8 1.7 0.7 0.1 0.5 85.7 6.7 9.8 0.9 9.1 13.6 0.0 28.8 1.7 40.9 0.0 29.8 48.6 0.5 0.0 0.3 0.3 0.0 2.9 1.3 6.6 52.7 0.0 0.3 2.6 2.3 0.3 18.7 4.8 17.9 0.2 43.1 42.4 16.8 0.7 21.0 13.0 55.3 0.2 0.1 62.2 70.1 32.6 1.7 0.3 15.1 1.5 12.6 75.9 0.4 45.3 0.1 1.4 2.6 45.9 5.1 258.6 5.8 21.1 0.0 0.5 35.3 0.7 37.3 10.4 5.0 30.7 21.6 6.6 6.3 1.1 0.0 20.1 0.9 15.2 11.2 1.7 1.9 1.3 1.8 1.5 1.6 1.6 1.6 1.7 1.9 2.0 2.3 1.6 0.0 1.9 1.3 24.7 2.8 45.7 79.5 3.4 0.2 69.7 56.6 0.4 7.2 18.4 1.8 4.2 231.1 4.1 22.0 0.0 5.9 1.2 1.7 0.2 4.0 0.0 32.4 1.5 3.9 14.1 2.3 57.1 4.2 0.0 0.0 0.4 0.0 43.7 0.0 1.1 8.9 2.0 7.2 78.2 0.3 0.0 23.3 21.4 1.0 2.5 0.1 1.0 0.5 0.8 63.8 22.3 0.0 22.4 63.5 1.0 0.1 2.2 0.5 0.0 0.3 1.4 0.4 1.4 2.1 2.3 763.3 9.5 0.0 51.1 65.6 KCNS1 Kv9.1 ENSG00000124134 "Potassium voltage-gated channel modifier subfamily S member 1" Q96KK3 20 45091214-45101127 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 22.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.0;Cholangiocytes: 7.2;Collecting duct cells: 1.8;Excitatory neurons: 6.2" "Cancer enriched" "Detected in many" 5 "cervical cancer: 6.1" "Region enhanced" "Detected in many" "cerebral cortex: 22.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBF TERT88: 1.3;HHSteC: 2.1;hTEC/SVTERT24-B: 1.0;THP-1: 1.8;U-87 MG: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.46e-2)" "unprognostic (2.95e-3)" "unprognostic (2.03e-1)" "unprognostic (3.11e-4)" "unprognostic (8.91e-3)" "unprognostic (6.01e-3)" "unprognostic (7.47e-2)" "unprognostic (8.94e-2)" "unprognostic (4.37e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (6.74e-2)" "unprognostic (4.65e-2)" "unprognostic (6.35e-2)" "unprognostic (5.62e-2)" "unprognostic (3.06e-2)" "unprognostic (1.15e-1)" "unprognostic (1.39e-1)" 0.0 0.4 0.9 0.1 2.9 0.1 0.2 0.0 22.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.1 4.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.5 2.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 0.1 0.4 0.4 0.1 0.1 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.8 0.0 0.9 0.2 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 2.9 0.0 22.8 4.1 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 2.0 0.3 0.0 0.4 0.1 0.1 0.0 0.0 0.3 0.1 1.1 7.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 6.2 0.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.1 KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 220.2;Inhibitory neurons: 240.5;Oligodendrocyte precursor cells: 310.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 3.2;hTERT-RPE1: 9.0;SCLC-21H: 7.5;SH-SY5Y: 5.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA051218: AB_2681392" "unprognostic (5.06e-2)" "unprognostic (2.94e-2)" "unprognostic (8.01e-2)" "unprognostic (5.10e-6)" "unprognostic (1.22e-3)" "unprognostic (1.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "unprognostic (9.56e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.67e-5)" "unprognostic (3.30e-4)" "unprognostic (2.95e-2)" "unprognostic (4.75e-1)" "unprognostic (1.72e-3)" 1.0 0.6 0.9 0.1 2.0 0.0 0.4 0.0 2.0 0.4 0.3 0.5 0.2 0.3 0.4 1.0 0.5 1.4 1.8 2.5 3.3 0.3 2.8 1.8 0.1 0.0 0.2 3.8 0.1 0.0 0.9 0.2 0.0 1.0 0.5 0.1 0.5 0.6 0.1 0.3 0.4 0.5 0.6 0.2 0.5 1.1 1.0 0.1 1.1 0.8 0.1 0.8 0.4 0.5 0.0 0.1 1.8 0.0 0.2 0.2 0.0 0.0 1.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.9 0.0 3.2 0.0 0.0 1.2 0.0 0.4 0.1 9.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 2.4 0.0 0.1 0.0 0.1 0.0 0.0 0.5 7.5 5.6 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.0 0.0 2.0 2.5 3.3 0.0 0.2 0.0 0.6 1.0 0.5 0.8 41.7 1.1 6.8 0.0 0.4 0.2 0.0 0.6 0.0 0.0 0.1 1.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.2 0.8 0.0 0.0 220.2 0.0 0.0 9.3 0.0 0.0 0.0 6.1 2.5 6.2 0.0 0.0 240.5 0.0 0.0 0.0 0.7 3.3 6.5 0.0 1.8 58.1 0.0 0.0 0.0 310.7 6.1 0.0 0.0 4.9 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.4 4.0 0.6 0.2 0.0 0.0 0.0 0.0 3.9 0.0 0.2 KCTD14 MGC2376 ENSG00000151364 "Potassium channel tetramerization domain containing 14" Q9BQ13 11 78015715-78046191 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 13.7;Breast myoepithelial cells: 12.8;Exocrine glandular cells: 17.1;Gastric mucus-secreting cells: 14.3;Intestinal goblet cells: 20.8;Prostatic glandular cells: 14.3;Proximal tubular cells: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 26.1;Hep G2: 29.0;RPTEC TERT1: 45.9;U-2 OS: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041118, HPA042181" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Vesicles, Cytosol" "HPA041118: AB_10963117, HPA042181: AB_10968059" "unprognostic (7.37e-3)" "unprognostic (4.27e-2)" "unprognostic (7.03e-2)" "unprognostic (6.93e-2)" "unprognostic (1.59e-2)" "unprognostic (2.28e-2)" "unprognostic (2.04e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.96e-5)" "prognostic favorable (8.01e-4)" "prognostic unfavorable (1.05e-4)" "unprognostic (3.19e-1)" "prognostic favorable (6.92e-5)" "unprognostic (2.42e-2)" "unprognostic (2.05e-1)" "prognostic favorable (5.93e-4)" "unprognostic (1.63e-1)" 3.4 23.1 2.0 1.6 2.0 0.1 20.4 5.1 2.9 10.4 3.2 8.1 4.9 3.4 14.3 1.5 11.7 6.7 0.6 2.1 2.1 11.5 10.3 8.2 0.3 1.9 2.3 0.8 27.2 8.3 2.5 1.3 2.2 7.0 11.9 1.6 28.7 19.1 0.2 1.9 5.2 2.1 1.6 0.6 20.8 0.6 2.5 1.3 15.9 0.6 0.5 2.3 1.4 1.7 0.0 3.5 0.6 0.5 1.3 0.8 3.5 1.8 1.6 3.4 8.4 13.5 8.8 0.1 9.3 1.1 0.4 1.0 0.6 26.1 8.9 0.5 13.2 0.0 3.0 29.0 4.9 0.2 0.1 4.0 0.7 13.9 11.0 2.5 1.0 0.2 0.3 0.1 1.4 0.2 0.3 0.8 6.5 0.5 0.5 0.4 0.0 0.0 45.9 3.5 2.3 0.2 0.0 0.2 4.5 0.8 1.4 1.1 0.8 0.2 20.2 0.7 0.4 0.3 0.2 0.2 0.2 0.2 3.7 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.3 0.0 0.2 0.2 0.2 0.0 0.0 2.0 2.0 5.1 2.9 2.1 2.1 1.9 2.3 2.2 1.6 2.5 1.7 0.6 3.2 10.8 0.0 0.2 0.4 12.2 2.0 2.8 0.4 13.7 12.8 0.0 1.5 4.1 5.5 0.0 0.6 0.3 5.2 3.9 2.6 0.3 2.7 2.0 0.9 4.8 0.0 0.0 17.1 1.3 1.1 14.3 3.7 1.3 0.5 0.0 4.8 0.2 0.0 0.0 20.8 0.0 0.0 0.0 0.0 3.4 0.4 1.8 0.0 0.1 2.1 0.0 0.0 0.0 10.5 6.6 5.3 0.0 14.3 2.2 15.1 0.1 0.0 0.0 0.0 1.8 0.2 0.3 0.7 0.1 0.7 0.3 0.7 8.5 7.4 KCTD15 MGC25497 ENSG00000153885 "Potassium channel tetramerization domain containing 15" Q96SI1 19 33795933-33815763 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 44.4;Granulosa cells: 94.8;Hepatic stellate cells: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.8;eosinophil: 5.9;intermediate monocyte: 3.3;myeloid DC: 2.5;non-classical monocyte: 4.8" "Group enriched" "Detected in many" 6 "dendritic cells: 2.5;granulocytes: 5.9;monocytes: 4.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050822 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA050822: AB_2681250" "unprognostic (1.26e-2)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (6.62e-3)" "unprognostic (1.67e-2)" "unprognostic (2.66e-2)" "unprognostic (3.09e-2)" "unprognostic (5.60e-2)" "unprognostic (6.33e-2)" "unprognostic (5.58e-2)" "unprognostic (2.76e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.65e-8)" "unprognostic (1.40e-1)" "unprognostic (1.89e-3)" "unprognostic (6.13e-2)" "unprognostic (7.30e-2)" 19.2 6.3 29.4 11.3 28.0 6.1 14.2 24.9 34.9 38.8 15.0 41.3 7.0 43.1 3.2 34.8 36.1 10.8 19.1 28.7 29.6 24.7 12.9 24.7 3.0 26.0 30.2 22.7 32.5 4.5 10.3 11.0 24.2 25.0 6.0 15.2 11.6 19.0 6.0 73.2 15.7 20.7 25.8 17.4 23.3 10.5 30.2 1.3 23.0 6.4 4.1 32.0 31.3 23.3 16.7 37.5 33.2 50.8 10.8 5.7 26.2 21.6 4.0 11.7 6.1 21.2 11.1 0.1 47.6 30.3 5.5 19.3 24.3 16.9 4.4 18.1 42.7 68.5 25.3 20.7 29.8 13.3 12.0 11.2 69.4 4.5 26.5 0.0 23.2 9.8 17.3 0.4 2.0 42.0 0.5 37.8 30.4 27.9 62.8 32.0 17.9 6.3 13.3 7.5 25.7 88.0 42.0 59.0 80.0 14.1 43.7 34.7 38.3 54.7 48.9 1.1 3.8 40.9 2.3 27.2 0.1 23.0 68.4 0.6 1.8 5.9 0.0 3.3 0.1 0.0 0.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.5 0.7 29.4 28.0 24.9 34.9 28.7 29.6 26.0 30.2 24.2 25.8 30.2 23.3 17.8 0.0 1.7 44.4 0.3 15.8 3.3 4.1 10.8 3.5 5.4 5.0 3.2 1.5 2.9 0.0 10.4 0.2 0.4 0.9 3.9 0.7 0.7 3.4 15.1 15.3 1.2 4.2 1.9 8.4 0.4 5.5 1.5 2.5 8.8 94.8 27.8 2.0 1.2 1.7 5.3 3.6 0.0 3.7 5.4 1.9 4.4 3.7 5.4 4.7 3.1 5.0 0.0 11.1 0.3 2.1 1.0 9.1 0.1 3.9 0.3 0.2 0.7 11.7 0.0 3.1 8.7 0.0 1.9 14.3 19.5 0.3 0.7 2.4 1.9 3.1 KCTD17 FLJ12242 ENSG00000100379 "Potassium channel tetramerization domain containing 17" Q8N5Z5 22 37051736-37063390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Ubl conjugation pathway" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 113.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 90.8" HPA018459 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA018459: AB_1852169" "unprognostic (1.09e-2)" "unprognostic (2.33e-1)" "unprognostic (1.09e-1)" "unprognostic (1.61e-2)" "unprognostic (5.38e-2)" "unprognostic (3.09e-3)" "prognostic unfavorable (3.59e-5)" "unprognostic (1.89e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-1)" "prognostic favorable (4.22e-5)" "unprognostic (8.62e-2)" "prognostic unfavorable (5.13e-12)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (2.32e-1)" "unprognostic (6.94e-2)" 8.2 15.6 64.8 9.8 113.7 2.4 6.7 46.0 71.6 14.2 44.4 15.9 3.4 14.9 1.8 7.2 10.7 8.5 26.6 68.0 54.1 5.8 3.5 9.3 10.6 44.8 70.4 13.7 3.7 7.8 43.0 6.5 52.4 11.2 5.2 3.6 3.4 9.0 1.7 21.1 10.4 9.4 43.8 11.1 7.9 46.0 83.8 7.0 7.6 3.0 6.9 16.9 13.0 55.5 15.9 20.5 31.7 23.7 14.9 14.8 1.2 16.2 15.6 25.9 22.3 4.4 4.6 12.2 10.9 20.8 20.3 4.2 10.0 19.0 10.9 23.8 26.8 5.2 5.6 4.9 22.1 0.0 6.1 17.3 9.2 26.6 5.8 17.5 33.6 15.9 1.2 13.2 16.5 12.8 11.0 0.3 20.3 9.4 17.4 19.8 8.4 3.6 6.7 4.1 26.4 32.9 15.0 14.1 7.5 6.6 3.8 4.2 19.6 33.5 31.2 16.0 12.0 17.7 5.5 2.0 29.6 7.3 18.6 0.0 0.8 0.0 0.9 1.0 0.9 1.2 0.6 0.9 0.9 0.4 0.8 0.6 0.0 1.6 0.4 0.2 1.0 0.4 64.8 113.7 46.0 71.6 68.0 54.1 44.8 70.4 52.4 43.8 83.8 55.5 8.8 0.0 0.5 11.1 5.8 1.5 4.6 2.8 1.2 17.3 1.3 1.5 5.0 4.3 0.8 5.5 2.1 0.4 5.0 17.7 0.0 11.9 24.9 0.7 12.7 9.7 13.1 0.8 22.4 6.1 2.8 9.9 4.1 0.9 4.5 12.0 12.8 0.5 9.2 13.5 11.6 5.3 0.0 9.6 17.0 28.1 10.5 9.8 3.6 1.9 13.0 16.4 8.2 4.5 7.1 3.2 16.0 9.1 4.6 1.2 0.5 2.5 1.5 7.8 0.0 7.8 11.7 19.7 7.1 1.3 4.8 7.5 8.5 10.2 7.0 2.4 KCTD4 bA321C24.3 ENSG00000180332 "Potassium channel tetramerization domain containing 4" Q8WVF5 13 45192853-45194717 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 24.6;choroid plexus: 9.4" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 2.6;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 9.5" "Group enriched" "Detected in some" 5 "glioma: 1.2;renal cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 20.7;hTERT-RPE1: 12.5;RPTEC TERT1: 11.8;U-138 MG: 13.9;U-87 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040734 Uncertain Approved "Centriolar satellite" NA NA "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" "Centriolar satellite" "HPA040734: AB_10963227" "unprognostic (1.36e-1)" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.19e-2)" "unprognostic (1.70e-1)" "unprognostic (4.68e-2)" "unprognostic (1.74e-1)" "unprognostic (1.66e-3)" "unprognostic (1.63e-1)" "unprognostic (1.73e-1)" "unprognostic (2.15e-1)" "unprognostic (2.98e-2)" 0.1 0.0 20.2 0.0 24.6 0.1 0.5 8.3 17.6 0.1 9.4 1.2 0.2 0.0 0.0 0.0 0.0 0.7 0.2 16.6 11.3 0.2 0.0 0.0 0.0 10.9 10.7 0.0 0.2 0.0 1.8 0.2 9.7 0.0 0.2 0.0 0.5 0.1 0.0 3.1 0.5 0.7 12.4 0.0 0.0 0.0 13.2 0.0 0.0 0.2 0.0 0.0 0.1 13.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.5 0.0 0.2 0.0 0.0 0.0 0.5 0.6 20.7 0.0 0.0 2.9 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 5.7 12.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 13.9 0.0 0.0 3.1 0.0 0.0 0.0 27.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 24.6 8.3 17.6 16.6 11.3 10.9 10.7 9.7 12.4 13.2 13.8 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 1.0 0.0 0.0 0.0 10.1 9.5 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 KDF1 "C1orf172, FLJ34633, RP11-344H11.3" ENSG00000175707 "Keratinocyte differentiation factor 1" Q8NAX2 1 26949562-26960468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.6;Ductal cells: 29.4;Syncytiotrophoblasts: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 36 "B-cells: 3.4;T-cells: 6.2" "Cell line enhanced" "Detected in some" "A-431: 24.9;BEWO: 20.8;CAPAN-2: 22.7;HaCaT: 21.4;HBEC3-KT: 30.3;hTCEpi: 38.5;OE19: 39.3;SK-BR-3: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA028634, HPA028639" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Cytosol "HPA028634: , HPA028639: AB_10599191" "unprognostic (2.58e-1)" "unprognostic (1.23e-1)" "unprognostic (6.46e-2)" "unprognostic (1.50e-2)" "unprognostic (1.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (8.45e-2)" "unprognostic (9.09e-2)" "unprognostic (9.01e-2)" "unprognostic (2.73e-1)" "unprognostic (3.91e-1)" "prognostic favorable (3.04e-13)" "unprognostic (1.38e-3)" "unprognostic (7.83e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.40e-4)" 0.1 1.1 0.4 1.3 0.3 0.1 10.3 1.6 1.3 4.0 0.3 8.9 12.4 0.9 19.7 20.2 7.4 2.9 0.4 0.4 0.2 11.0 4.7 4.4 0.8 0.3 0.3 0.1 16.2 12.5 10.4 3.9 0.4 7.2 7.1 1.3 12.8 4.6 0.0 17.7 10.5 0.3 0.2 0.6 10.6 2.6 0.3 2.3 10.0 0.0 3.4 4.8 8.3 0.7 24.9 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 12.1 22.7 0.0 0.9 0.0 0.0 21.4 0.0 30.3 0.0 0.1 0.4 0.0 0.0 4.4 0.3 0.0 0.0 0.1 38.5 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.0 14.7 0.0 0.1 1.7 39.3 0.1 0.0 0.0 3.7 5.5 11.7 14.9 0.0 0.2 25.2 0.1 2.7 16.1 0.4 0.2 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.2 2.5 4.3 3.0 0.1 3.4 6.2 3.8 0.0 0.0 0.0 0.0 0.2 1.7 0.4 0.3 1.6 1.3 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.7 0.2 12.8 8.8 0.0 0.8 0.0 14.3 0.0 10.8 0.6 15.1 16.3 0.3 12.8 2.5 14.7 0.0 32.6 1.5 17.2 25.4 29.4 0.4 7.3 0.8 0.7 7.8 0.0 0.2 23.2 26.5 0.6 13.7 8.0 0.0 0.1 0.0 4.4 2.7 0.0 0.1 13.1 0.0 0.3 0.0 0.1 0.3 0.1 0.0 0.0 0.2 1.1 0.0 0.0 0.1 21.8 25.2 0.0 0.4 16.8 26.2 10.1 5.1 2.5 0.0 0.0 0.3 6.3 7.5 14.4 0.0 29.7 1.2 0.0 16.9 19.0 KDM1B "AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2" ENSG00000165097 "Lysine demethylase 1B" Q8NB78 6 18155329-18223854 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 7.2;monocytes: 8.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031269, HPA055597" Uncertain Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA031269: AB_10601587, HPA055597: " "unprognostic (1.93e-1)" "unprognostic (7.53e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.57e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (5.57e-3)" "unprognostic (1.32e-2)" "unprognostic (8.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.16e-1)" "unprognostic (3.17e-2)" "unprognostic (6.68e-2)" "unprognostic (3.02e-2)" "unprognostic (2.90e-1)" "unprognostic (7.36e-2)" "unprognostic (3.53e-1)" 5.9 7.6 5.6 11.4 7.6 27.2 6.3 5.3 7.8 7.6 7.6 14.1 8.0 5.7 3.7 9.1 13.4 6.0 6.8 6.6 5.9 7.8 7.4 8.8 10.4 6.9 6.7 6.7 5.9 3.2 5.8 4.6 6.1 5.2 12.2 12.0 5.7 4.7 17.3 11.2 8.9 6.9 6.2 10.5 5.6 15.7 5.6 10.8 27.2 9.1 9.4 7.7 8.1 9.4 15.1 9.7 11.2 23.0 13.8 20.5 24.5 11.7 12.6 7.5 10.2 16.3 7.4 34.1 31.6 19.2 22.8 15.5 17.8 20.8 16.0 31.6 14.6 17.2 8.6 15.0 6.7 25.5 17.5 10.3 23.4 21.5 17.7 12.1 7.7 15.9 38.3 5.2 12.7 12.6 14.1 10.5 3.8 31.6 12.8 26.8 20.3 24.4 10.7 19.8 34.2 10.6 9.7 23.5 22.9 11.7 22.3 20.3 6.5 16.9 9.5 11.9 15.5 5.2 15.9 20.0 6.4 18.9 37.8 1.2 4.6 7.2 0.5 8.6 0.3 1.2 0.5 0.5 3.7 1.3 0.5 0.2 4.9 0.3 6.9 1.6 0.7 1.3 5.6 7.6 5.3 7.8 6.6 5.9 6.9 6.7 6.1 6.2 5.6 9.4 4.9 0.0 8.2 14.7 8.7 12.7 5.7 3.8 7.4 5.0 7.6 6.6 10.4 11.5 10.4 1.8 10.4 2.7 3.0 23.0 1.9 6.6 0.7 36.2 10.0 4.2 6.7 3.8 19.0 4.3 5.1 5.8 8.2 15.5 2.5 3.3 4.2 7.7 7.5 5.0 10.8 9.6 10.2 36.7 11.7 0.7 3.7 20.6 7.2 22.5 27.7 6.6 8.2 16.1 23.8 7.2 21.2 6.8 3.7 5.4 6.2 11.2 21.0 15.5 0.0 6.9 6.2 0.7 18.2 9.7 15.9 1.4 5.6 3.1 10.6 6.6 KDM2A "CXXC8, DKFZP434M1735, FBL11, FBL7, FBXL11, FLJ00115, JHDM1A, KIAA1004, LILINA" ENSG00000173120 "Lysine demethylase 2A" Q9Y2K7 11 67119263-67258082 "Enzymes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012272, HPA044251" Supported Supported Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB012272: , HPA044251: " "unprognostic (7.43e-2)" "unprognostic (1.84e-1)" "unprognostic (4.09e-1)" "unprognostic (8.66e-2)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (6.05e-2)" "unprognostic (2.84e-1)" "unprognostic (4.46e-1)" "unprognostic (2.04e-3)" "unprognostic (3.27e-2)" "unprognostic (5.08e-2)" "unprognostic (2.67e-2)" "unprognostic (3.30e-1)" "unprognostic (1.05e-1)" "unprognostic (5.61e-2)" "unprognostic (9.45e-3)" 19.5 13.2 10.7 27.2 10.6 47.1 19.7 18.0 12.1 24.3 14.1 23.3 14.7 29.1 17.4 31.9 19.3 19.0 17.4 10.6 11.2 14.3 19.9 24.0 27.5 12.6 10.7 24.5 13.0 16.1 13.1 18.0 10.9 21.6 17.1 18.5 21.3 19.2 33.8 29.4 23.9 24.0 9.7 27.0 18.9 29.0 11.9 27.8 19.0 24.5 28.7 23.9 25.9 10.9 49.9 31.8 17.6 27.7 17.1 27.0 13.5 21.5 26.6 41.0 27.9 48.7 25.4 38.8 37.5 33.3 23.8 48.2 31.3 22.5 33.1 66.4 13.4 28.9 39.2 11.7 16.9 24.5 38.1 21.7 23.9 39.4 25.7 20.7 29.9 22.7 27.4 54.4 18.6 35.4 32.5 18.1 36.1 29.8 25.6 39.9 29.4 21.4 14.7 33.7 24.2 18.9 71.0 38.6 39.0 21.6 59.9 23.9 38.7 25.0 16.7 34.5 18.8 29.3 35.4 25.4 22.0 17.2 17.8 0.4 1.1 0.3 2.5 0.8 2.7 3.6 1.9 2.3 0.6 3.6 1.9 1.9 2.7 2.7 0.5 0.9 2.6 1.9 10.7 10.6 18.0 12.1 10.6 11.2 12.6 10.7 10.9 9.7 11.9 10.9 41.4 38.5 35.8 75.1 56.6 41.2 23.3 23.4 75.7 75.3 40.3 30.9 31.1 34.3 31.0 16.5 137.6 23.9 77.5 43.2 0.0 17.3 20.6 84.8 63.0 38.4 31.8 22.1 89.4 14.5 13.4 32.4 42.8 112.3 27.3 42.1 29.3 35.5 21.5 95.9 89.8 27.5 24.4 46.5 59.6 11.2 21.5 49.1 19.6 104.0 43.3 19.8 33.0 96.0 99.5 25.9 25.5 23.0 72.5 37.2 21.2 10.3 40.0 111.7 19.7 40.2 32.3 52.0 38.1 78.7 47.7 32.3 66.9 33.8 29.5 48.7 KDM2B "CXXC2, Fbl10, FBXL10, JHDM1B, PCCX2" ENSG00000089094 "Lysine demethylase 2B" Q8NHM5 12 121429096-121581023 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071257 Supported Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 5: NTERA-2 - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA071257: " "unprognostic (7.67e-2)" "unprognostic (3.72e-3)" "unprognostic (2.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.74e-6)" "unprognostic (1.16e-1)" "unprognostic (5.45e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-1)" "prognostic favorable (8.64e-4)" "unprognostic (1.77e-1)" "unprognostic (4.44e-3)" "unprognostic (1.44e-2)" "unprognostic (3.90e-2)" "unprognostic (7.07e-2)" "unprognostic (4.82e-2)" 9.7 8.4 7.1 18.9 8.7 16.9 10.0 12.9 10.7 15.6 7.4 12.2 8.2 11.5 5.5 20.2 12.4 7.0 8.7 7.3 5.6 11.1 15.6 13.1 22.9 8.3 6.3 15.2 11.6 10.8 9.4 7.3 9.2 9.5 7.6 9.7 12.6 6.1 15.2 28.0 18.9 8.3 5.4 21.4 10.9 14.0 7.8 23.1 11.2 6.1 21.6 12.3 16.9 9.0 15.2 19.1 31.3 9.8 8.7 7.6 34.8 12.4 19.1 17.8 14.9 24.0 7.7 69.3 20.6 11.2 9.9 13.1 34.3 13.7 14.4 29.3 24.0 38.0 15.9 19.4 10.3 44.0 29.5 6.9 7.4 16.9 12.3 19.1 12.7 33.6 31.4 8.8 8.5 20.4 54.5 51.8 55.8 11.0 15.1 61.0 16.4 34.1 9.8 24.5 37.1 21.4 23.8 14.0 14.4 29.5 25.0 49.2 17.3 19.0 15.4 19.2 13.9 23.9 21.3 64.5 17.6 35.2 12.3 4.5 2.8 2.4 6.3 2.3 4.9 9.5 4.9 3.5 3.9 9.3 4.3 5.8 0.4 2.0 1.7 3.5 4.6 3.4 7.1 8.7 12.9 10.7 7.3 5.6 8.3 6.3 9.2 5.4 7.8 9.0 6.8 0.0 10.6 28.1 36.8 17.0 7.1 4.0 13.6 20.1 10.3 6.7 14.6 14.3 5.4 11.0 12.5 6.7 43.3 3.8 11.7 7.5 57.0 13.0 7.0 8.8 5.4 22.5 36.2 5.8 11.2 8.3 9.2 12.0 14.0 16.5 9.7 15.4 24.4 15.2 41.6 6.1 6.1 21.1 61.0 60.1 7.8 25.5 16.0 26.2 48.0 4.1 24.7 31.2 44.1 5.8 4.7 7.2 34.1 11.2 6.5 4.2 5.7 16.1 19.7 6.5 8.1 11.4 18.3 13.9 15.2 6.6 24.8 6.2 7.4 6.3 KDM4C "GASC1, JMJD2C, KIAA0780, TDRD14C" ENSG00000107077 "Lysine demethylase 4C" Q9H3R0 9 6720863-7175648 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 206.9;Inhibitory neurons: 235.9;Microglial cells: 148.0;Oligodendrocyte precursor cells: 189.0;Oligodendrocytes: 347.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069357 Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA069357: AB_2686128" "unprognostic (1.56e-2)" "unprognostic (1.91e-2)" "unprognostic (4.38e-2)" "unprognostic (1.38e-1)" "unprognostic (3.52e-1)" "unprognostic (4.36e-2)" "unprognostic (2.50e-2)" "unprognostic (6.89e-3)" "unprognostic (2.37e-1)" "unprognostic (2.34e-2)" "unprognostic (3.65e-2)" "unprognostic (2.03e-2)" "unprognostic (1.92e-1)" "unprognostic (7.87e-3)" "unprognostic (1.21e-1)" "unprognostic (2.23e-2)" "unprognostic (1.64e-3)" 10.0 9.6 9.8 12.8 12.0 30.1 11.3 30.6 11.5 10.2 13.5 13.7 13.1 10.4 11.8 10.1 10.3 9.7 7.8 9.9 11.1 8.7 11.1 10.6 19.1 13.8 11.7 11.5 16.1 17.8 11.8 8.9 13.3 9.9 16.1 28.9 11.6 8.8 8.3 15.2 14.4 10.8 9.7 13.9 15.1 9.8 11.9 23.6 13.4 6.0 18.8 10.3 10.7 16.4 17.2 9.8 4.0 6.0 13.4 14.3 11.8 7.6 9.6 8.5 8.1 11.3 9.1 20.1 4.6 10.3 8.7 5.1 8.6 12.8 11.1 60.6 7.4 27.9 13.8 15.1 12.4 10.8 18.5 12.5 8.4 6.7 14.0 21.1 10.4 16.4 4.7 13.4 9.3 8.3 18.0 40.4 7.0 18.0 3.8 10.8 3.4 12.9 12.3 9.2 14.0 8.3 7.1 12.7 6.8 10.7 6.6 17.5 11.0 8.4 4.0 9.9 7.5 10.2 8.1 21.3 8.2 10.0 3.3 7.5 7.1 13.5 9.6 7.7 11.2 12.1 10.4 11.2 9.6 13.8 11.3 8.8 1.6 11.2 13.1 3.7 10.0 8.0 9.8 12.0 30.6 11.5 9.9 11.1 13.8 11.7 13.3 9.7 11.9 16.4 11.3 6.4 14.4 110.4 40.6 19.9 7.9 10.5 18.8 22.6 11.2 8.0 9.2 11.5 9.2 7.3 45.9 5.2 22.7 10.3 3.9 7.0 84.8 10.0 12.2 9.4 9.7 42.1 206.9 6.2 5.3 6.9 34.7 16.8 8.8 6.0 6.8 13.0 6.7 11.8 235.9 14.7 6.1 10.0 19.4 83.3 9.6 16.5 7.2 148.0 15.0 3.3 19.6 189.0 347.2 7.6 9.5 9.4 27.1 6.2 14.1 4.0 10.8 28.3 13.1 7.3 7.6 6.6 5.4 14.4 23.9 5.9 28.2 6.2 8.1 8.0 KDM5A "JARID1A, RBBP2" ENSG00000073614 "Lysine demethylase 5A" P29375 12 280057-389320 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 45.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006201 Supported "Nuclear bodies,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear bodies" Cytosol "HPA006201: AB_1079160" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (1.12e-1)" "unprognostic (4.46e-2)" "unprognostic (1.60e-1)" "unprognostic (3.53e-3)" "unprognostic (1.81e-2)" "unprognostic (5.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.77e-3)" "unprognostic (6.11e-2)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (2.60e-2)" "unprognostic (7.69e-2)" 8.1 8.7 5.8 11.4 8.3 45.5 11.1 11.6 8.5 8.6 10.0 8.2 7.2 9.7 7.1 8.9 7.6 8.0 5.2 6.2 6.5 7.8 9.9 8.8 15.3 6.8 5.7 11.0 9.4 10.1 4.2 11.8 6.5 8.6 9.9 9.6 6.7 7.3 5.5 12.5 7.3 9.4 6.0 13.5 8.8 21.1 6.7 21.6 9.1 7.6 14.4 8.7 7.2 15.0 14.4 25.3 18.3 14.2 16.1 15.2 20.3 12.5 16.5 18.4 19.8 15.2 17.0 24.0 3.9 21.0 16.0 13.3 19.2 14.2 21.9 37.9 15.9 29.3 26.5 9.0 13.0 38.6 22.1 16.6 13.1 22.6 29.9 18.8 18.8 21.0 17.9 32.7 15.7 9.7 27.9 11.0 28.4 12.3 7.9 25.7 47.5 11.4 8.8 32.6 7.0 20.5 24.5 11.0 13.0 25.0 11.9 24.0 26.0 12.0 17.0 13.6 21.1 11.5 13.6 53.7 15.5 16.5 18.0 64.5 21.8 44.4 31.4 25.0 32.3 27.1 24.6 25.9 22.8 32.0 26.3 22.8 63.0 35.8 28.9 32.0 20.9 22.5 5.8 8.3 11.6 8.5 6.2 6.5 6.8 5.7 6.5 6.0 6.7 15.0 53.1 64.1 61.6 61.7 80.6 33.0 22.2 30.1 48.9 69.0 35.3 27.9 38.2 31.5 39.0 35.0 116.7 48.8 103.3 51.3 3.9 37.4 96.8 60.2 72.8 51.6 69.7 51.3 71.7 31.6 34.7 47.2 39.8 99.8 54.4 106.9 42.8 30.9 30.2 87.5 59.1 40.0 40.7 52.5 37.5 32.5 48.4 63.9 26.6 57.1 82.9 48.3 105.0 68.3 85.9 38.7 37.0 55.7 73.1 32.4 33.6 11.8 40.2 71.9 59.2 64.0 59.9 137.1 104.8 50.1 47.6 71.1 80.1 67.5 40.1 42.0 KIAA0513 ENSG00000135709 KIAA0513 O60268 16 85027751-85094230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.3" "Cell type enhanced" "Detected in many" "Early spermatids: 50.2;Excitatory neurons: 53.5;Inhibitory neurons: 53.3;Late spermatids: 199.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "granulocytes: 25.8;monocytes: 23.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012866, HPA014431" Enhanced Uncertain Nucleoplasm,Cytosol NA NA 67000 "Cluster 18: Basophils - Vesicular transport" "Cluster 6: Brain - Smell perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Cytosol" "HPA012866: AB_1852321, HPA014431: AB_1852322" "unprognostic (1.98e-2)" "unprognostic (2.47e-2)" "unprognostic (2.35e-1)" "unprognostic (1.69e-2)" "unprognostic (1.49e-2)" "unprognostic (9.37e-3)" "unprognostic (2.90e-2)" "unprognostic (8.56e-2)" "unprognostic (1.38e-1)" "unprognostic (4.85e-2)" "prognostic favorable (1.72e-5)" "unprognostic (7.52e-2)" "unprognostic (1.94e-3)" "unprognostic (7.88e-2)" "unprognostic (4.00e-1)" "unprognostic (2.33e-2)" "unprognostic (2.34e-1)" 5.4 11.3 23.5 9.9 35.8 17.1 2.5 35.8 63.3 7.7 0.0 11.0 4.6 5.2 2.7 7.7 3.3 4.7 4.6 41.2 3.3 3.6 2.5 7.5 5.9 12.1 2.6 2.7 15.2 4.1 32.6 3.9 2.6 9.2 6.1 9.2 6.9 4.8 10.2 10.6 6.8 5.6 0.8 8.2 10.8 5.8 2.8 2.8 2.4 3.7 6.6 14.9 6.4 27.4 6.7 7.1 4.7 6.8 8.6 6.4 1.2 6.6 10.4 9.2 5.3 3.2 3.1 2.2 2.8 8.0 5.6 5.8 4.4 10.5 5.7 4.9 3.6 4.3 1.9 1.7 4.1 0.5 5.9 11.9 5.5 10.6 1.4 3.9 5.0 4.6 19.1 5.4 8.3 10.5 0.8 1.8 4.6 7.8 5.6 0.8 6.0 1.4 8.7 4.8 13.7 2.1 7.7 12.7 3.1 4.7 10.3 1.3 10.0 5.7 4.3 8.7 2.3 8.4 1.6 4.8 7.5 3.3 6.2 24.6 11.1 17.9 1.4 13.4 0.4 0.0 0.9 0.9 4.1 0.1 0.8 0.9 25.8 1.3 23.9 5.9 0.3 5.3 23.5 35.8 35.8 63.3 41.2 3.3 12.1 2.6 2.6 0.8 2.8 27.4 0.9 6.4 5.8 7.5 2.6 4.0 7.8 12.4 2.2 17.9 2.7 1.1 8.3 2.8 15.3 1.8 6.2 0.6 8.0 16.0 0.0 2.8 50.2 2.8 7.5 3.3 11.4 0.4 53.5 4.7 0.8 6.9 10.7 4.9 2.5 1.7 3.3 2.9 6.9 48.8 53.3 8.6 10.2 21.5 4.6 199.5 16.1 30.9 3.6 11.2 24.5 3.1 3.1 8.5 7.0 9.1 7.2 26.7 16.5 15.0 4.8 1.8 23.9 5.4 0.0 5.4 3.4 4.1 4.1 1.2 4.4 3.4 4.6 4.8 5.2 29.8 KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.7;hTCEpi: 103.0;RT4: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" 7.9 93.0 14.6 7.0 10.7 1.2 24.3 1.8 15.6 14.5 27.1 42.5 51.7 10.1 12.2 76.7 23.5 16.0 5.1 12.4 6.5 43.9 12.0 18.2 1.2 5.2 5.5 22.3 70.7 37.8 9.1 8.4 4.3 40.9 30.9 1.2 68.3 20.2 3.1 74.1 45.9 6.7 4.2 1.4 61.8 5.1 7.7 8.2 39.4 3.2 12.1 22.2 28.1 8.8 65.7 33.6 5.4 9.3 2.4 4.6 24.6 7.9 15.3 8.9 8.7 37.0 125.7 0.2 32.3 11.6 26.5 95.1 10.3 67.8 4.6 0.2 13.4 13.6 49.4 30.4 4.0 0.2 33.3 1.7 103.0 23.6 28.2 40.1 18.6 2.7 20.1 0.4 4.3 54.3 0.3 0.6 11.0 56.3 20.9 8.7 6.7 16.7 85.8 117.5 4.6 4.7 49.5 70.1 9.7 33.7 74.7 4.3 17.6 14.9 39.3 13.7 17.3 0.8 0.3 0.3 15.2 2.3 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 10.7 1.8 15.6 12.4 6.5 5.2 5.5 4.3 4.2 7.7 8.8 5.7 12.8 56.9 5.5 0.6 73.9 37.0 52.7 59.2 0.6 69.8 42.3 3.8 72.9 52.0 27.6 2.1 15.6 1.5 154.4 9.8 47.3 4.2 54.7 5.6 8.7 28.9 1.3 10.2 66.7 5.2 6.7 51.0 50.2 27.8 10.2 4.6 10.6 2.9 0.0 5.2 54.0 48.8 0.8 6.5 5.1 8.7 2.2 7.2 3.7 2.4 0.8 0.0 2.0 0.4 60.7 64.6 4.9 0.3 80.9 84.7 14.8 60.7 0.1 6.6 3.1 7.5 3.8 2.7 59.7 83.1 7.9 2.1 59.9 65.4 99.6 KIAA2012 ENSG00000182329 KIAA2012 2 202073255-202205188 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 6.9;choroid plexus: 3.1;fallopian tube: 9.2" "Group enriched" "Detected in some" 6 "Early spermatids: 38.9;Endometrial ciliated cells: 12.3;Excitatory neurons: 24.8;Late spermatids: 28.6;Respiratory ciliated cells: 43.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077834 Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 49: Ciliated cells - Cilium organization" "HPA077834: " "unprognostic (1.91e-2)" "unprognostic (3.17e-1)" "unprognostic (2.56e-1)" "unprognostic (5.35e-2)" "unprognostic (2.85e-2)" "unprognostic (3.22e-2)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "unprognostic (7.35e-2)" "unprognostic (6.31e-2)" "unprognostic (7.81e-2)" "unprognostic (6.94e-5)" "unprognostic (1.60e-1)" "unprognostic (9.44e-2)" "unprognostic (3.37e-1)" "unprognostic (9.95e-3)" 0.0 0.0 1.0 0.0 2.0 0.0 0.0 0.1 1.3 0.3 3.1 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 1.9 1.1 0.0 0.9 0.8 0.0 5.6 6.9 0.0 0.0 0.0 0.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.0 0.1 1.3 1.9 1.1 5.6 6.9 3.1 4.9 1.9 0.9 0.2 3.2 0.0 1.0 0.1 0.0 0.3 0.0 0.0 2.9 0.4 0.1 1.0 0.0 1.8 0.0 2.1 0.1 0.2 0.0 0.0 0.0 38.9 12.3 0.6 0.4 0.0 0.0 24.8 0.2 0.1 0.6 0.0 0.6 0.0 0.2 1.1 4.8 0.1 3.3 2.8 0.0 0.0 0.0 0.0 28.6 0.0 0.2 0.0 0.0 0.0 0.3 0.0 1.5 0.9 0.0 0.0 0.0 0.0 0.3 0.2 0.0 43.0 2.4 0.0 0.8 0.2 1.5 3.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 KIF11 "Eg5, HKSP, KNSL1, TRIP5" ENSG00000138160 "Kinesin family member 11" P52732 10 92574105-92655395 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 37.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 39.1;Granulosa cells: 20.7;Spermatocytes: 38.0;Spermatogonia: 23.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006916, HPA010093, HPA010568, CAB017617" Enhanced Supported "Mitotic spindle,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Mitotic spindle" "CAB017617: AB_2131098, HPA006916: AB_1848033, HPA010093: AB_2668281, HPA010568: AB_1848034" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.35e-2)" "unprognostic (2.12e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (8.19e-7)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (6.59e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.35e-3)" "unprognostic (7.23e-2)" "unprognostic (9.08e-2)" "unprognostic (2.01e-1)" 1.1 0.7 0.5 8.5 0.7 19.4 2.5 0.4 0.6 1.4 0.5 6.3 5.5 1.8 1.0 6.7 1.0 1.2 0.6 0.5 0.5 1.0 1.1 1.3 17.5 0.6 0.6 0.6 0.5 0.7 0.3 3.9 0.6 1.0 7.4 0.8 1.3 0.7 0.2 6.0 5.3 2.5 0.5 2.9 3.9 11.6 0.4 37.9 1.6 0.3 18.5 2.3 2.3 0.6 103.1 45.2 100.6 94.5 7.3 10.5 24.2 72.6 62.8 78.8 78.1 39.6 67.2 111.1 36.5 34.4 32.9 72.0 72.1 36.5 92.4 68.3 41.3 70.5 41.4 42.4 1.4 116.0 63.0 3.6 3.3 61.4 55.9 18.3 50.0 46.1 51.2 126.4 61.1 41.4 99.3 65.8 40.3 42.5 30.7 106.6 98.8 40.2 21.0 30.1 30.0 42.9 56.4 25.9 29.2 34.1 67.9 37.6 28.6 35.7 51.3 37.1 96.9 35.4 58.3 113.4 29.5 82.3 50.3 0.8 0.0 0.1 0.0 0.3 0.3 0.6 0.4 0.4 0.2 0.1 0.1 0.2 0.2 1.0 0.1 0.1 1.1 0.2 0.5 0.7 0.4 0.6 0.5 0.5 0.6 0.6 0.6 0.5 0.4 0.6 0.4 0.0 2.0 1.3 3.5 2.9 1.1 1.6 3.4 1.0 1.8 1.8 1.7 1.5 2.5 1.8 0.0 6.7 2.3 2.9 1.9 0.5 16.3 3.4 4.3 2.0 0.0 39.1 2.1 0.6 11.4 4.7 9.2 4.9 0.0 20.7 2.2 0.4 8.2 0.0 1.8 4.3 4.1 4.6 3.4 4.4 0.9 4.0 0.0 0.0 1.0 0.7 2.1 2.5 1.1 0.2 0.4 0.7 15.2 0.8 0.5 0.6 3.7 0.4 0.0 1.7 3.7 38.0 23.4 12.6 3.3 1.5 4.5 2.5 8.0 1.7 KIF13B "GAKIN, KIAA0639" ENSG00000197892 "Kinesin family member 13B" Q9NQT8 8 29067278-29263124 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 64.5;parathyroid gland: 161.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 140.2;Oligodendrocytes: 371.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025023, HPA049655" Enhanced NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA025023: AB_1852471, HPA049655: AB_2732555" "unprognostic (1.37e-1)" "unprognostic (4.31e-1)" "prognostic favorable (8.92e-4)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "prognostic favorable (6.26e-4)" "unprognostic (1.04e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-2)" "unprognostic (9.69e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (9.76e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" 7.4 11.7 25.9 6.8 47.6 5.1 9.2 34.9 30.6 8.7 16.6 18.3 16.1 6.7 9.4 8.4 7.1 8.4 5.3 20.0 29.4 18.5 10.2 8.5 4.3 47.3 43.7 7.2 10.9 161.5 10.0 3.8 42.1 10.9 13.8 7.9 15.6 8.5 4.7 20.0 15.7 5.5 29.3 8.9 19.2 6.6 40.1 5.1 9.0 3.0 4.6 9.5 6.1 64.5 12.4 13.2 4.6 3.8 7.5 4.3 6.7 0.7 2.9 3.9 6.2 8.3 6.9 2.6 6.9 0.8 7.1 8.2 3.7 2.1 5.1 3.9 3.6 6.6 1.8 8.4 7.2 1.8 19.2 5.0 3.9 8.9 3.6 8.3 17.1 4.9 8.6 9.5 12.9 3.8 9.7 3.1 2.3 17.4 2.2 5.5 10.6 4.9 17.0 13.2 1.3 9.1 2.4 8.0 11.7 4.8 5.9 3.7 22.8 2.8 7.6 0.8 5.6 6.9 11.1 4.4 16.4 3.4 13.2 0.1 1.5 1.7 1.5 1.1 0.7 1.4 0.6 0.9 0.5 0.8 0.5 0.6 0.7 0.9 0.6 2.2 0.6 0.5 25.9 47.6 34.9 30.6 20.0 29.4 47.3 43.7 42.1 29.3 40.1 64.5 22.2 44.8 24.8 30.0 16.5 4.5 13.8 17.2 5.2 13.3 23.5 11.2 5.3 20.0 36.8 35.0 60.5 6.4 35.8 95.8 11.7 25.7 8.0 55.3 12.7 14.2 25.2 7.4 26.7 25.0 0.9 10.0 55.0 140.2 41.0 10.6 13.9 18.6 8.9 16.8 35.3 44.1 36.7 25.7 6.3 3.5 8.1 24.4 7.2 41.2 12.1 9.5 12.3 47.3 371.1 39.7 58.0 20.3 42.5 28.1 34.7 17.8 34.9 26.2 6.6 36.4 7.4 6.3 7.7 9.8 6.8 5.1 31.8 5.9 36.0 32.5 KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.5;lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 27.1;Granulosa cells: 13.2;Spermatocytes: 22.8;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038061, HPA058220" Uncertain Supported "Midbody ring,Cytosol" Yes Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Midbody ring" "HPA038061: AB_10669515, HPA058220: AB_2683642" "unprognostic (1.84e-1)" "unprognostic (7.15e-2)" "unprognostic (2.00e-2)" "unprognostic (1.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.47e-3)" "unprognostic (1.02e-1)" "unprognostic (2.54e-5)" "unprognostic (2.31e-2)" "unprognostic (0.00e+0)" "unprognostic (6.28e-3)" "unprognostic (3.31e-1)" "unprognostic (8.14e-2)" "unprognostic (7.44e-2)" 0.2 0.2 0.1 2.0 0.0 6.5 0.3 0.2 0.3 0.2 0.1 0.9 1.2 0.3 0.0 1.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.2 3.2 0.1 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.0 1.2 0.1 0.1 0.0 0.0 1.0 1.1 0.6 0.0 0.6 0.6 2.5 0.1 10.9 0.1 0.0 3.2 0.4 0.3 0.1 29.7 17.3 26.8 15.0 0.8 3.0 14.8 20.0 11.7 18.7 16.8 10.5 15.1 18.0 7.0 9.6 11.6 23.0 21.6 13.3 26.7 22.1 11.3 28.8 24.8 10.3 0.1 45.5 15.7 0.6 0.6 20.9 17.8 4.0 13.5 26.3 44.0 22.6 23.5 12.1 26.9 14.2 22.6 8.7 15.0 24.3 35.4 22.8 6.3 8.3 12.7 14.0 28.3 9.5 11.0 19.8 12.9 11.6 11.1 14.7 17.3 16.2 35.3 8.2 8.9 25.8 8.6 24.0 30.5 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 1.0 0.0 0.0 0.0 1.9 2.4 1.0 1.1 0.6 2.3 1.5 1.9 0.8 0.0 0.9 0.0 2.1 4.2 0.6 2.5 0.0 0.2 4.1 3.7 2.2 1.6 0.0 27.1 1.1 0.0 7.7 3.3 10.2 5.0 2.5 13.2 2.5 0.9 5.4 0.0 0.9 5.2 0.0 2.9 1.9 2.5 0.6 2.3 0.0 0.0 0.4 0.5 0.0 0.5 0.8 0.3 0.0 0.7 11.3 1.2 0.2 0.1 1.4 0.8 6.6 1.4 2.1 22.8 16.3 8.3 0.9 1.4 2.3 0.7 4.3 1.9 KIF15 "HKLP2, KNSL7, NY-BR-62" ENSG00000163808 "Kinesin family member 15" Q9NS87 3 44761721-44873376 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 5.0;lymphoid tissue: 9.2;testis: 7.3" "Group enriched" "Detected in many" 4 "Early spermatids: 177.5;Late spermatids: 78.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA035516, HPA035517, HPA061469" Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA035516: AB_2674664, HPA035517: AB_10671935, HPA061469: " "unprognostic (2.26e-1)" "unprognostic (1.85e-1)" "prognostic favorable (3.12e-4)" "unprognostic (3.49e-2)" "unprognostic (2.69e-1)" "unprognostic (5.17e-3)" "unprognostic (6.68e-7)" "unprognostic (1.35e-2)" "unprognostic (1.51e-2)" "unprognostic (6.94e-2)" "unprognostic (3.14e-4)" "unprognostic (2.72e-2)" "unprognostic (0.00e+0)" "unprognostic (1.38e-2)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.58e-1)" 0.2 0.1 0.1 1.2 0.1 5.0 0.4 0.2 0.2 0.3 0.0 1.4 1.4 0.3 0.0 1.1 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.2 2.2 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.1 0.2 1.6 0.1 0.2 0.1 0.0 0.8 1.4 0.4 0.1 0.4 0.8 7.3 0.1 9.2 0.0 0.0 2.2 0.3 0.4 0.1 7.5 3.9 17.6 12.8 1.2 1.4 3.9 8.6 5.3 10.8 9.0 6.6 7.2 13.8 2.8 3.1 4.0 6.3 10.1 4.7 13.1 11.6 2.3 14.9 7.7 8.4 0.1 15.6 6.6 0.3 0.2 7.3 7.1 1.6 8.6 18.4 9.3 17.2 8.2 3.9 30.0 5.7 18.2 9.7 7.0 11.9 19.0 7.9 2.4 4.9 8.2 7.8 14.2 4.6 2.9 4.6 7.7 11.7 4.8 10.4 8.5 8.8 11.5 7.2 12.7 17.3 5.5 16.3 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 2.6 1.6 1.9 0.4 0.9 0.0 0.1 0.5 0.8 1.8 0.0 0.7 0.0 2.1 3.3 0.8 2.5 0.0 0.8 177.5 1.3 1.7 1.2 0.0 28.0 3.2 0.0 5.9 1.9 5.1 1.4 0.0 12.3 0.0 0.2 3.5 0.0 3.8 2.6 0.0 1.6 1.4 78.0 0.0 1.8 0.0 0.0 0.3 0.7 1.0 3.0 4.7 0.5 0.1 0.4 9.7 0.5 0.5 0.1 0.2 0.0 0.0 0.4 1.9 20.2 14.7 6.0 1.0 0.7 3.1 1.1 5.3 0.5 KIF18A "DKFZP434G2226, PPP1R99" ENSG00000121621 "Kinesin family member 18A" Q8NI77 11 28020619-28108156 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 8.2;lymphoid tissue: 9.6;testis: 13.7" "Cell type enhanced" "Detected in many" "Early spermatids: 43.1;Spermatocytes: 78.7;Spermatogonia: 28.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.1;memory B-cell: 1.0;NK-cell: 1.4;T-reg: 1.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA039312, HPA039484" Approved Supported "Microtubules,Cytokinetic bridge" Yes Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Cytokinetic bridge" "HPA039312: AB_10794087, HPA039484: AB_10795252" "unprognostic (3.79e-1)" "unprognostic (2.63e-1)" "unprognostic (7.09e-3)" "unprognostic (3.80e-2)" "unprognostic (6.56e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-7)" "unprognostic (2.43e-3)" "unprognostic (2.04e-3)" "unprognostic (1.23e-2)" "unprognostic (1.72e-4)" "unprognostic (4.41e-2)" "unprognostic (0.00e+0)" "unprognostic (7.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.43e-1)" "unprognostic (2.50e-1)" 0.2 0.1 0.0 1.9 0.1 8.2 0.7 0.0 0.1 0.7 0.1 1.6 1.5 0.5 0.3 1.4 0.3 0.5 0.0 0.1 0.1 0.3 0.3 1.0 4.7 0.1 0.1 0.1 0.1 0.1 0.1 1.5 0.1 0.3 2.0 0.6 0.3 0.4 0.2 1.2 1.4 0.8 0.1 0.7 0.6 13.7 0.2 9.6 1.1 0.1 4.6 0.7 0.5 0.1 27.9 27.4 27.2 19.0 0.9 3.7 9.1 28.3 13.2 44.2 46.0 9.2 11.0 23.3 10.0 14.7 24.1 27.2 23.4 11.1 61.4 23.4 14.2 15.2 17.8 11.8 2.1 22.6 13.4 6.8 1.4 15.5 18.1 7.8 17.2 19.0 24.6 20.0 25.2 14.8 23.1 16.7 13.4 18.0 11.1 17.8 65.0 11.6 12.5 8.0 16.3 12.6 23.7 11.1 7.8 16.5 23.8 6.9 10.1 35.0 27.2 33.2 37.4 7.9 19.8 23.4 21.0 16.5 25.2 4.1 0.0 0.3 0.1 0.2 0.3 1.0 0.4 0.2 0.3 0.4 0.3 0.1 0.0 1.4 0.0 0.3 1.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 1.2 3.2 0.0 0.0 4.7 2.3 1.3 1.4 1.2 0.3 1.3 2.9 0.5 0.0 2.2 0.0 6.2 4.6 2.8 1.9 0.0 0.6 43.1 3.4 2.5 1.1 1.8 15.4 0.2 0.9 7.1 5.4 1.5 3.4 4.5 9.7 1.4 0.0 2.2 0.0 0.1 1.9 0.0 1.6 1.4 8.7 0.6 1.4 0.0 1.0 1.1 0.7 1.0 0.5 0.9 0.5 0.1 0.4 5.1 0.2 0.2 0.6 1.7 1.9 0.0 2.5 1.9 78.7 28.3 4.3 1.0 1.6 3.9 2.7 3.6 0.5 KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947773 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 9.0;Extravillous trophoblasts: 3.8;Granulosa cells: 5.9;Oligodendrocyte precursor cells: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" HPA024205 Enhanced Supported "Nucleoplasm,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Microtubule ends" "Nuclear bodies, Cytosol" "HPA024205: AB_1852472" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (4.61e-2)" "unprognostic (1.13e-2)" "unprognostic (4.17e-1)" "unprognostic (7.27e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (3.34e-3)" "prognostic unfavorable (6.90e-4)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (8.18e-2)" "unprognostic (0.00e+0)" "unprognostic (4.69e-3)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (1.68e-2)" 0.4 0.4 0.3 3.8 0.4 12.7 0.2 0.7 0.3 0.9 0.3 2.0 2.7 0.4 0.0 5.1 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.8 5.7 0.5 1.1 0.1 0.1 0.0 0.1 1.9 0.6 0.2 1.7 0.1 0.7 0.0 0.4 3.0 2.5 1.1 0.3 2.9 1.5 2.9 0.6 14.4 0.2 0.0 4.7 0.6 1.6 0.5 31.5 41.7 35.3 32.8 0.8 3.0 28.1 25.8 10.3 34.6 26.9 34.0 27.4 28.3 10.9 10.8 21.5 34.0 25.1 11.3 17.9 56.6 36.4 35.4 51.7 22.1 0.0 30.0 30.2 0.7 0.6 29.7 12.2 4.7 17.9 29.2 28.1 48.0 18.2 25.9 60.0 31.1 25.4 30.4 28.9 43.5 51.8 19.2 5.8 16.7 26.2 24.7 18.0 16.1 9.8 17.0 30.2 21.6 11.2 49.9 48.0 28.8 56.8 15.1 15.7 34.4 16.3 22.9 33.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.4 0.7 0.3 0.3 0.4 0.5 1.1 0.6 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.9 0.4 0.1 0.2 0.0 0.5 0.5 0.4 2.6 0.0 0.0 0.0 0.0 2.4 0.4 1.9 0.0 0.0 0.0 0.3 0.8 0.6 0.0 9.0 0.3 0.0 3.8 1.4 1.5 0.5 0.0 5.9 0.4 0.3 2.3 0.0 0.3 1.6 0.0 2.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 7.1 0.1 0.1 0.0 0.0 2.1 0.2 0.3 0.0 0.0 0.3 0.0 0.2 0.8 1.1 2.9 2.5 0.4 0.8 1.3 0.3 3.2 0.3 KIF1C "SAX2, SPAX2, SPG58" ENSG00000129250 "Kinesin family member 1C" O43896 17 4997950-5028401 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 244.8;choroid plexus: 142.7;heart muscle: 185.0;skeletal muscle: 561.0;tongue: 389.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 315.4;Distal enterocytes: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024602, HPA045020" Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024602: AB_1852480, HPA045020: AB_2679187" "unprognostic (3.89e-2)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-1)" "unprognostic (8.97e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "unprognostic (6.69e-2)" "unprognostic (8.31e-2)" "unprognostic (1.45e-1)" "unprognostic (4.90e-3)" "prognostic favorable (2.26e-9)" "unprognostic (1.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.41e-1)" "unprognostic (7.10e-3)" 54.6 18.6 200.1 25.1 230.9 6.3 36.3 184.0 210.0 33.9 142.7 63.3 53.3 44.4 7.9 75.7 31.5 28.0 185.0 164.4 175.0 37.9 46.4 49.6 10.0 219.0 216.9 24.1 51.6 55.1 10.5 18.6 197.0 36.4 33.2 4.3 38.3 36.7 561.0 53.4 51.4 36.3 200.7 26.5 51.2 17.7 200.8 11.3 38.7 389.2 16.7 51.4 37.3 244.8 104.1 97.6 32.2 69.4 74.5 44.5 51.0 80.8 64.3 63.2 38.3 70.7 24.5 16.6 46.7 127.2 41.2 105.3 58.4 107.2 44.6 40.2 68.7 12.0 124.1 57.4 50.7 4.9 34.6 46.0 109.9 85.2 58.0 59.6 87.2 14.5 45.9 28.4 62.6 61.5 14.7 8.0 25.1 68.1 63.4 15.1 54.1 17.2 55.7 71.9 7.8 15.3 114.2 63.0 34.9 30.6 62.0 14.9 185.5 84.8 63.7 62.2 99.3 10.8 9.9 8.9 62.6 20.9 43.0 0.5 0.4 0.7 0.2 0.4 0.2 0.4 0.2 0.2 0.3 0.4 0.2 0.2 1.2 0.3 0.2 0.2 0.3 0.1 200.1 230.9 184.0 210.0 164.4 175.0 219.0 216.9 197.0 200.7 200.8 244.8 24.8 54.5 50.6 6.5 6.8 16.8 19.0 25.6 12.5 12.5 24.8 14.2 315.4 48.6 28.1 25.8 0.0 14.8 6.5 168.9 19.6 32.2 71.6 13.0 15.1 37.8 14.4 4.4 5.7 43.1 14.0 21.9 51.0 29.3 12.7 21.6 37.1 82.7 16.1 23.5 7.3 77.3 12.2 18.5 11.0 32.1 16.8 11.9 16.0 10.3 16.1 7.7 6.2 4.5 5.0 63.0 83.8 42.5 11.4 44.1 92.9 42.9 18.4 5.8 6.6 35.0 35.1 18.7 23.6 21.3 20.2 23.3 7.9 12.4 65.4 36.6 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 24.6;testis: 11.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.0;Erythroid cells: 24.6;Extravillous trophoblasts: 13.1;Granulosa cells: 11.1;Spermatocytes: 21.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 6.6;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.6;T-cells: 2.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036909, HPA036910" Approved Uncertain "Nucleoplasm,Cytokinetic bridge" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 0.7 0.8 0.0 4.5 0.1 14.1 1.3 0.1 0.1 1.0 0.1 3.3 3.5 1.4 0.0 6.6 0.4 0.8 0.5 0.0 0.1 0.4 0.9 0.9 8.6 0.1 0.2 0.2 0.2 0.1 0.0 5.4 0.1 0.2 5.1 0.0 1.0 0.1 0.1 4.4 2.8 5.8 0.0 1.9 2.1 11.7 0.5 24.6 0.5 0.1 13.1 1.6 2.0 0.1 87.8 59.5 127.8 84.4 6.7 12.3 53.9 75.0 68.9 162.3 121.4 111.9 80.5 38.8 39.2 96.5 60.6 85.9 121.7 142.5 160.9 56.4 57.4 57.2 101.1 70.7 0.3 28.2 25.1 4.8 2.3 86.2 49.5 27.1 106.7 53.9 24.4 70.4 113.9 81.5 47.6 26.7 80.6 51.8 63.7 51.2 128.5 39.5 43.9 42.3 37.8 37.5 144.1 47.9 30.9 161.6 60.8 28.5 51.1 41.6 60.5 38.0 126.4 36.0 37.5 42.0 26.7 81.1 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.5 0.1 0.3 0.0 1.7 0.0 0.8 0.4 0.4 2.9 0.0 0.0 1.1 1.3 0.3 0.0 0.7 0.0 0.0 11.0 0.1 2.8 0.0 0.1 1.0 1.0 1.9 1.7 0.0 24.6 0.0 0.0 13.1 3.1 2.6 1.3 4.5 11.1 3.3 0.4 6.1 0.0 0.0 1.6 6.1 2.2 0.4 2.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 3.0 0.3 1.2 0.0 0.9 0.0 0.0 0.5 4.4 21.7 7.5 5.3 0.4 1.0 0.7 0.8 3.4 0.6 KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701590-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.2;lymphoid tissue: 9.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 89.2;Spermatocytes: 165.4;Spermatogonia: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Cytosol" Yes Yes "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "Midbody, Cytosol" "HPA050214: AB_2681053" "unprognostic (2.13e-1)" "unprognostic (3.01e-2)" "unprognostic (1.72e-2)" "unprognostic (3.20e-2)" "unprognostic (2.65e-1)" "unprognostic (7.39e-2)" "unprognostic (8.95e-5)" "unprognostic (3.32e-3)" "unprognostic (2.01e-2)" "unprognostic (8.14e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.62e-2)" "prognostic unfavorable (3.06e-6)" "unprognostic (4.22e-3)" "unprognostic (2.70e-1)" "unprognostic (2.51e-2)" "unprognostic (6.43e-2)" 1.3 0.7 0.3 4.5 1.0 10.2 2.5 2.4 0.4 1.5 0.1 3.2 3.6 2.3 0.4 3.3 1.2 1.3 0.9 0.3 0.3 1.3 1.3 1.5 8.0 0.5 0.3 2.7 0.7 1.1 0.2 2.4 0.6 1.3 4.0 1.1 1.0 0.9 0.4 2.5 3.4 2.2 0.4 3.3 2.5 6.9 0.6 9.8 1.8 0.7 7.5 1.6 0.7 0.6 84.8 17.0 24.3 21.7 4.7 8.0 20.2 33.8 30.9 34.8 36.3 22.6 38.1 32.5 10.4 17.3 13.0 41.8 27.3 18.9 46.4 39.5 18.6 33.1 30.5 19.5 1.4 57.1 26.3 3.4 2.8 33.7 33.9 12.2 22.8 17.0 32.2 36.5 31.3 14.6 33.6 10.8 25.0 13.8 16.1 23.1 47.8 14.3 10.7 11.2 7.7 13.9 24.4 11.0 12.2 17.3 28.5 16.3 17.9 22.2 22.1 29.1 55.3 10.1 29.5 43.2 21.1 49.4 16.8 13.1 2.4 4.2 5.5 4.1 6.8 13.0 7.4 6.1 1.3 16.0 8.6 8.0 0.2 3.0 4.5 5.2 9.5 2.2 0.3 1.0 2.4 0.4 0.3 0.3 0.5 0.3 0.6 0.4 0.6 0.6 11.5 3.2 13.5 2.3 36.4 17.7 6.2 20.8 6.8 14.3 8.3 8.5 8.7 1.5 10.7 0.0 10.4 21.4 32.3 8.8 3.9 6.9 13.1 10.6 13.2 11.0 1.2 89.2 8.1 4.7 38.1 13.2 14.8 12.9 44.4 37.2 9.3 4.4 20.7 13.5 9.5 8.6 16.2 21.0 17.9 10.5 8.1 17.1 5.4 23.4 11.3 7.5 24.7 9.0 9.1 4.1 5.7 8.6 51.4 3.7 8.9 3.2 6.6 9.8 6.6 16.9 17.1 165.4 96.7 26.1 14.1 5.2 34.2 12.9 25.5 5.2 KIF23 "KNSL5, MKLP-1, MKLP1" ENSG00000137807 "Kinesin family member 23" Q02241 15 69414246-69448427 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 24.2;Erythroid cells: 42.3;Extravillous trophoblasts: 32.4;Granulosa cells: 22.4;Spermatocytes: 70.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 4.6" "Group enriched" "Detected in many" 13 "granulocytes: 4.6;monocytes: 1.2;T-cells: 1.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB010414, HPA045208, HPA068831" Uncertain Enhanced "Nucleoplasm,Midbody ring,Mitotic spindle" Yes Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Midbody ring, Mitotic spindle" "CAB010414: AB_631959, HPA045208: AB_2679254, HPA068831: AB_2686045" "unprognostic (1.29e-1)" "unprognostic (2.40e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.86e-1)" "unprognostic (7.99e-3)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.43e-3)" "unprognostic (4.25e-3)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.69e-5)" "unprognostic (5.85e-3)" "unprognostic (0.00e+0)" "unprognostic (1.15e-2)" "unprognostic (2.59e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" 1.0 1.5 0.3 5.7 0.2 21.6 1.4 0.2 0.3 1.5 1.4 4.1 3.9 2.0 0.1 5.3 0.9 1.3 0.6 0.3 0.2 4.6 0.5 1.5 7.9 0.2 0.3 0.7 0.5 0.4 0.1 6.4 0.3 0.9 5.0 0.2 1.1 1.2 0.1 3.7 3.8 4.2 0.2 2.2 2.0 10.6 0.3 15.9 0.3 0.2 9.8 1.8 2.1 0.2 100.7 81.5 64.2 59.0 3.7 7.3 36.3 105.3 57.0 154.8 120.6 50.2 72.4 56.8 31.4 53.1 78.6 110.5 121.6 39.5 158.7 52.9 60.2 55.3 78.8 30.7 2.1 55.6 48.3 3.3 4.2 71.8 60.5 19.4 52.0 46.9 36.0 70.2 95.4 44.1 31.2 28.2 71.6 35.5 33.2 37.0 133.8 31.2 39.3 49.7 32.5 25.3 120.4 51.9 44.9 74.5 50.6 25.3 34.5 90.0 120.8 62.0 157.6 26.3 74.3 48.4 31.5 72.2 78.0 0.0 1.2 4.6 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 1.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.3 0.2 0.3 0.2 0.4 0.0 0.5 0.0 2.3 1.9 3.7 4.2 0.0 0.2 1.8 2.8 0.8 5.7 4.7 7.3 2.1 24.2 1.4 3.3 3.9 1.8 13.3 13.1 3.6 2.2 1.8 42.3 1.8 0.0 32.4 5.8 3.6 8.7 2.5 22.4 3.9 0.3 8.1 0.0 1.0 3.1 0.0 2.8 3.4 4.8 0.9 3.2 0.0 1.0 8.1 0.2 0.0 0.0 0.2 0.4 0.4 1.9 6.8 1.6 0.8 0.9 3.6 0.1 6.6 0.4 8.2 70.8 20.9 11.3 1.0 2.5 4.2 3.6 8.6 3.3 KIF24 "bA571F15.4, C9orf48, FLJ10933, FLJ43884" ENSG00000186638 "Kinesin family member 24" Q5T7B8 9 34252381-34311371 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 11.1" "Cell type enhanced" "Detected in some" "Astrocytes: 32.3;Early spermatids: 28.9;Late spermatids: 41.6;Spermatocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 19 "basophil: 2.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 2.8" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA020643 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA020643: AB_2131749" "unprognostic (2.68e-1)" "prognostic favorable (1.33e-4)" "unprognostic (9.44e-2)" "unprognostic (3.82e-3)" "unprognostic (3.11e-1)" "unprognostic (2.11e-3)" "unprognostic (1.40e-2)" "unprognostic (8.38e-3)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (1.40e-2)" "unprognostic (8.68e-3)" "unprognostic (1.17e-1)" "unprognostic (1.30e-3)" "unprognostic (2.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.50e-1)" 0.2 0.6 0.7 0.9 1.0 2.1 0.7 0.6 0.7 0.6 4.4 0.9 0.6 0.6 1.4 0.9 3.2 0.4 0.5 0.8 0.8 0.9 0.3 0.6 1.3 1.9 2.3 0.4 0.5 1.5 1.0 0.6 1.3 0.4 1.0 0.4 0.3 0.5 0.7 0.9 0.6 0.7 1.5 0.3 0.6 11.1 0.8 3.9 1.2 0.6 1.6 0.3 0.4 0.8 9.8 6.4 7.5 6.2 0.6 1.0 2.8 5.3 3.4 7.0 8.4 3.1 3.0 7.6 1.6 2.5 4.5 4.5 7.6 4.6 7.2 4.9 3.3 3.5 10.7 1.9 0.2 7.2 5.3 0.4 0.9 9.1 3.8 1.3 3.2 5.3 3.6 6.0 3.9 4.0 8.7 6.7 3.0 4.5 3.8 8.0 4.6 2.1 2.9 2.5 3.5 3.4 6.5 3.3 0.9 2.9 3.6 3.5 2.6 6.5 7.1 5.1 6.5 1.7 2.9 4.1 4.4 3.5 8.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 1.0 0.6 0.7 0.8 0.8 1.9 2.3 1.3 1.5 0.8 0.8 0.3 0.0 1.1 32.3 0.7 0.4 0.2 0.7 0.6 0.3 0.7 1.1 0.9 1.5 1.6 1.8 0.0 0.6 0.3 0.7 0.0 0.4 28.9 8.2 0.8 0.4 0.0 3.0 7.2 0.2 1.0 0.7 2.0 0.8 0.0 1.5 0.0 0.0 0.7 0.0 3.5 0.8 2.0 0.3 0.3 41.6 0.9 0.4 0.0 3.7 0.1 0.2 0.0 10.1 9.2 0.2 0.0 1.9 2.1 0.1 0.3 0.4 11.0 0.4 0.0 0.5 0.4 14.5 6.9 1.0 0.9 0.3 0.3 0.8 0.7 0.1 KIF2C "CT139, KNSL6, MCAK" ENSG00000142945 "Kinesin family member 2C" Q99661 1 44739818-44767767 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 33.0;lymphoid tissue: 37.4;testis: 76.5" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1860.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in some" "white matter: 2.1" "Not detected" "Not detected" "HPA006219, HPA079172" Enhanced Supported Nucleoplasm,Midbody,Centrosome Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" Midbody "HPA006219: AB_2667540, HPA079172: " "unprognostic (3.29e-2)" "unprognostic (1.35e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.77e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (3.07e-7)" "unprognostic (7.49e-3)" "unprognostic (3.33e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (6.86e-4)" "unprognostic (4.27e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.33e-3)" "unprognostic (1.49e-1)" "unprognostic (1.86e-2)" "unprognostic (2.41e-1)" 0.7 0.8 0.7 7.0 0.7 33.0 1.6 2.3 0.7 1.8 1.1 6.2 5.5 1.8 0.7 7.3 0.9 1.3 1.3 0.6 1.1 0.8 0.7 1.3 16.4 1.1 0.9 0.6 0.5 1.3 0.4 5.4 1.4 0.8 7.6 0.8 1.3 0.7 0.9 6.0 5.1 3.2 0.9 3.7 3.5 76.5 0.8 37.4 1.1 0.7 19.2 2.1 2.7 0.8 119.7 45.8 99.6 79.8 5.3 11.6 66.6 86.9 62.1 175.0 151.3 77.6 84.2 136.2 41.3 43.2 121.7 55.2 102.8 59.6 158.2 89.1 44.4 162.1 83.3 65.5 0.6 121.5 71.8 2.7 5.8 125.0 60.3 16.5 57.6 95.4 130.4 113.1 112.4 46.5 127.5 72.9 97.1 58.4 56.5 101.1 149.3 86.4 29.6 42.8 68.3 48.5 116.1 81.6 71.5 71.9 47.2 90.7 34.7 62.9 124.2 69.0 155.6 59.4 65.0 195.3 40.3 115.4 123.9 0.0 0.0 0.0 0.9 0.0 0.0 0.6 1.7 1.2 0.1 0.1 0.3 0.2 0.0 2.0 0.1 0.8 2.9 0.5 0.7 0.7 2.3 0.7 0.6 1.1 1.1 0.9 1.4 0.9 0.8 0.8 0.1 0.0 0.5 1.6 1.3 1.8 0.5 2.4 0.0 1.0 0.9 0.9 1.6 0.0 1.7 1.8 2.1 12.2 1.9 2.9 1.9 0.3 461.1 1.2 1.4 1.6 0.0 34.5 0.8 0.4 23.4 3.2 3.1 2.1 0.0 13.0 2.9 0.2 9.2 0.0 1.0 3.5 0.0 1.9 1.5 1860.6 9.3 3.4 0.0 1.0 4.3 0.4 0.0 0.5 0.2 0.1 0.2 6.8 7.8 0.8 0.3 0.2 0.3 0.2 6.6 0.8 3.4 60.6 36.8 4.6 0.4 3.7 2.7 0.8 7.4 0.7 KIF4A "FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100" ENSG00000090889 "Kinesin family member 4A" O95239 X 70290104-70420886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA-binding, Motor protein" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 12.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.6;Erythroid cells: 29.5;Extravillous trophoblasts: 11.5;Granulosa cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034745, HPA034746, HPA061583" Approved Supported Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Midbody" "HPA034745: AB_10670978, HPA034746: AB_10670173, HPA061583: AB_2684564" "unprognostic (8.17e-3)" "unprognostic (2.78e-2)" "unprognostic (1.02e-2)" "unprognostic (3.46e-3)" "unprognostic (3.20e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.37e-6)" "unprognostic (2.18e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (3.79e-2)" "unprognostic (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" 0.3 0.3 0.3 3.2 0.2 11.2 0.7 0.1 0.3 0.6 0.3 3.7 3.1 0.8 0.0 3.6 1.5 0.5 0.2 0.2 0.5 0.2 0.5 0.5 5.5 0.9 0.7 0.1 0.1 0.1 0.5 2.3 0.6 0.1 4.5 0.6 0.5 0.1 0.1 2.2 3.3 1.3 0.7 2.4 1.7 1.5 0.6 12.6 0.2 0.0 6.6 0.9 1.1 0.2 60.2 41.1 61.0 30.1 2.9 5.1 24.0 44.7 23.8 59.7 51.6 46.7 34.3 36.7 27.4 22.1 46.2 35.1 66.6 24.2 66.8 42.5 33.4 41.7 50.1 33.4 0.7 46.7 27.8 1.7 1.5 49.6 28.2 7.3 37.0 27.7 53.8 79.1 57.0 38.7 43.0 23.1 61.7 63.8 43.2 47.1 82.2 34.6 14.5 23.4 40.1 33.5 72.9 30.5 18.6 30.6 24.5 18.1 26.0 39.3 50.6 42.6 54.1 22.6 41.7 52.0 20.8 50.4 60.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.2 0.1 0.3 0.2 0.5 0.9 0.7 0.6 0.7 0.6 0.2 0.1 0.0 0.5 1.3 1.3 1.8 0.3 1.4 0.6 0.2 1.1 0.8 0.4 1.5 0.2 0.0 0.0 7.0 0.9 2.2 0.0 0.0 0.4 18.6 1.5 1.3 1.2 29.5 1.9 0.0 11.5 2.1 3.1 1.6 0.0 12.2 1.1 0.1 5.3 0.0 1.9 4.6 2.0 1.3 0.7 0.8 0.0 1.4 0.0 0.0 0.2 3.1 0.0 2.0 0.7 0.1 0.1 0.0 8.2 0.4 0.3 0.1 0.4 0.0 0.0 0.2 2.9 8.7 5.4 7.2 0.3 1.8 1.8 1.3 6.6 0.5 KIFC1 "HSET, KNSL2" ENSG00000237649 "Kinesin family member C1" Q9BW19 6 33391823-33409896 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 47.5" "Cell type enhanced" "Detected in many" "Early spermatids: 32.0;Erythroid cells: 62.3;Extravillous trophoblasts: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 1.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055997, HPA062674" Enhanced Approved Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA055997: AB_2683001, HPA062674: AB_2684829" "unprognostic (7.33e-2)" "unprognostic (1.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.65e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (7.07e-8)" "unprognostic (6.34e-3)" "unprognostic (9.36e-3)" "unprognostic (8.58e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.83e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.17e-2)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (4.52e-1)" 1.1 1.1 0.2 10.6 0.3 39.7 2.2 0.3 1.2 2.5 0.4 8.0 8.8 1.8 0.2 11.7 0.8 1.5 0.6 0.7 0.3 0.8 1.0 2.3 24.6 0.4 0.7 2.0 0.7 0.3 0.6 5.5 0.5 0.9 8.2 0.4 2.1 0.2 0.2 9.8 8.1 4.1 0.2 5.3 4.7 12.3 0.6 47.5 0.7 0.4 24.9 2.7 3.9 0.5 133.5 47.9 120.6 124.2 5.2 8.1 64.0 82.5 48.4 122.6 104.6 80.6 53.3 120.2 38.3 41.5 102.0 88.1 87.1 60.7 79.7 114.3 60.3 93.9 71.6 73.5 0.5 96.0 75.7 2.5 4.7 73.2 38.8 13.8 64.2 87.5 76.0 112.3 81.0 86.2 125.7 103.2 47.5 67.6 48.4 129.7 110.7 61.4 38.4 42.8 100.1 57.2 54.3 91.9 44.1 51.3 78.7 105.4 32.2 74.6 104.6 56.2 128.9 58.2 132.4 126.1 18.8 94.8 101.0 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.6 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.0 1.6 0.5 0.2 0.3 0.3 1.2 0.7 0.3 0.4 0.7 0.5 0.2 0.6 0.5 0.4 0.0 2.5 1.0 4.1 5.6 1.5 4.6 2.2 0.4 2.8 2.2 0.5 0.0 1.9 0.0 0.0 18.7 3.7 8.8 0.0 0.7 32.0 2.7 1.9 2.4 0.0 62.3 0.3 0.0 39.6 4.2 4.1 6.1 1.3 15.0 1.8 0.3 14.3 0.0 0.3 8.0 2.0 2.4 9.8 12.0 0.3 4.7 3.6 1.0 3.1 0.3 0.0 1.0 0.6 0.3 2.1 0.7 12.0 0.9 2.1 0.7 0.8 0.5 0.0 2.5 7.5 13.9 9.6 14.4 3.7 6.7 5.7 0.6 12.1 3.1 KL ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;kidney: 128.7;parathyroid gland: 135.2" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 123.3" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 2.4;SK-BR-3: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.3;cerebral cortex: 6.7;hippocampal formation: 7.4;medulla oblongata: 4.2" "Secreted to blood" NA NA 510000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 3.3 1.4 0.9 0.8 3.1 0.1 2.5 0.8 1.5 1.8 47.1 2.1 2.7 1.2 8.8 1.1 0.8 1.3 1.1 4.2 1.1 128.7 0.4 3.5 1.0 0.5 0.5 0.1 1.2 135.2 0.3 30.4 0.5 8.0 0.9 0.0 0.8 2.5 0.7 0.6 2.6 1.2 0.6 2.4 2.0 0.5 0.8 0.5 1.3 1.5 0.5 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.1 0.8 1.5 4.2 1.1 0.5 0.5 0.5 0.6 0.8 0.5 15.8 0.0 0.5 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.7 12.9 0.0 0.2 0.0 0.4 5.9 0.0 1.8 0.1 2.5 10.2 16.3 0.4 1.2 0.0 0.1 1.6 0.0 0.1 0.0 0.1 1.1 0.2 2.8 0.0 0.5 1.1 0.0 0.9 1.0 0.8 0.3 1.9 0.0 6.5 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.6 1.8 123.3 0.7 0.0 0.0 1.1 2.3 1.4 0.5 0.0 0.1 0.1 1.1 0.1 1.9 0.1 KLC3 "KLC2L, KLCt, KNS2B" ENSG00000104892 "Kinesin light chain 3" Q6P597 19 45333434-45351520 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;skin 1: 104.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 142.0;Basal prostatic cells: 50.8;Ductal cells: 39.1;Prostatic glandular cells: 66.9;Suprabasal keratinocytes: 183.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 36.1;HaCaT: 16.2;HBEC3-KT: 10.5;hTCEpi: 12.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052797, HPA056508" Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" "Nucleoplasm, Cytosol" "HPA052797: AB_2681954, HPA056508: AB_2683159" "unprognostic (4.11e-2)" "unprognostic (3.71e-1)" "unprognostic (3.07e-4)" "prognostic unfavorable (1.46e-4)" "unprognostic (3.47e-3)" "unprognostic (1.13e-1)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.53e-1)" "unprognostic (1.75e-2)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (4.79e-3)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (4.14e-1)" "unprognostic (2.37e-1)" 0.3 0.2 0.5 0.3 1.1 3.0 3.3 1.3 0.8 10.0 0.0 0.1 0.1 0.2 2.1 26.1 0.3 0.2 0.2 0.4 0.2 5.9 0.2 0.9 0.3 0.5 0.0 0.2 4.0 4.0 2.7 0.2 0.2 2.6 0.2 1.0 11.6 1.0 0.9 104.1 0.3 0.0 0.0 0.3 0.5 3.7 0.2 1.0 0.7 0.0 1.8 0.2 20.5 0.7 36.1 0.2 0.2 0.4 0.1 0.1 2.8 0.2 0.0 0.0 0.1 3.5 6.5 0.3 2.8 0.0 3.7 16.2 2.2 10.5 0.2 0.8 5.3 0.1 1.1 0.7 0.0 0.3 2.2 0.0 12.9 0.1 2.5 0.4 0.0 0.5 0.6 0.4 0.1 4.7 0.1 0.4 0.8 0.6 1.1 5.6 0.0 0.3 0.3 1.3 4.5 0.7 0.3 7.3 1.0 0.4 6.5 0.1 0.0 0.4 3.6 0.3 0.4 0.7 0.8 0.3 0.2 0.2 0.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.0 0.5 1.1 1.3 0.8 0.4 0.2 0.5 0.0 0.2 0.0 0.2 0.7 0.2 0.0 2.4 0.3 0.0 142.0 50.8 17.5 14.8 0.8 10.3 25.3 0.4 2.8 7.3 1.8 0.0 0.2 0.2 0.2 9.8 39.1 3.0 0.9 0.3 1.7 0.0 2.7 0.3 3.1 0.7 1.4 0.0 2.4 0.0 6.7 0.4 0.0 0.3 1.7 0.4 0.5 6.1 0.0 10.9 12.0 1.8 0.4 14.2 0.0 0.8 0.7 0.0 0.0 0.0 11.8 0.0 0.4 0.0 66.9 0.0 1.4 3.8 2.0 0.0 1.1 2.5 0.6 11.3 25.6 183.3 0.7 1.0 0.0 0.1 22.0 KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "Kruppel like factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 242.0;skin 1: 234.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1105.5;Basal squamous epithelial cells: 757.5;Glandular and luminal cells: 678.2;Squamous epithelial cells: 1028.4;Suprabasal keratinocytes: 685.9;Urothelial cells: 1495.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 21 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 111.8;HaCaT: 128.8;HBEC3-KT: 112.2;hTCEpi: 156.1;OE19: 246.3;RT4: 136.3;SiHa: 114.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 23.2" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: AB_10673267" "unprognostic (7.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.03e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (3.97e-2)" "unprognostic (5.82e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (4.43e-2)" "unprognostic (1.42e-3)" "unprognostic (3.56e-3)" "unprognostic (3.98e-1)" "unprognostic (5.09e-2)" "unprognostic (1.54e-2)" 6.5 5.9 4.2 18.0 9.1 63.5 36.2 0.6 3.3 49.9 2.7 161.2 130.4 6.7 6.6 242.0 37.5 55.9 3.3 2.6 3.4 8.5 4.7 29.6 2.0 0.8 3.4 4.5 11.9 0.5 10.9 18.8 0.7 23.1 145.4 0.4 79.8 14.4 19.2 234.9 146.2 6.6 0.5 1.5 82.2 12.0 4.1 12.0 25.7 7.8 53.6 111.5 122.2 1.0 22.3 31.1 0.2 0.4 1.1 1.5 34.1 12.9 29.8 5.6 6.9 28.5 111.8 0.4 68.9 11.4 2.3 128.8 39.0 112.2 8.9 0.9 11.0 0.4 61.9 2.8 7.8 10.5 1.9 8.1 156.1 1.7 61.1 5.7 0.1 3.8 1.6 2.2 25.5 7.9 2.1 0.8 1.4 246.3 43.3 2.0 28.3 2.5 87.3 136.3 2.9 1.3 114.5 18.3 8.5 13.9 2.5 2.5 0.3 7.8 23.1 0.2 5.4 3.7 1.9 3.8 10.8 2.1 9.5 24.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 4.2 9.1 0.6 3.3 2.6 3.4 0.8 3.4 0.7 0.5 4.1 1.0 7.8 163.5 123.3 0.7 5.2 518.9 1105.5 185.6 757.5 0.4 79.9 57.0 6.0 91.5 218.5 36.8 2.1 77.8 4.6 420.7 21.5 31.8 448.3 302.1 44.1 12.5 203.2 0.4 1.6 46.1 98.5 33.4 425.1 678.2 3.8 0.9 2.2 4.7 6.1 10.1 11.6 387.4 46.8 0.9 34.6 241.4 6.5 12.4 58.7 1.9 4.3 0.0 1.0 1.0 0.6 88.6 374.9 1.5 15.7 632.1 260.0 3.5 159.3 0.2 0.0 38.4 32.4 8.8 26.3 1028.4 685.9 58.0 17.4 0.5 505.4 1495.5 KLF7 UKLF ENSG00000118263 "Kruppel like factor 7" O75840 2 207074137-207167267 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 95.2;Oligodendrocytes: 160.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003423, HPA030490" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA003423: , HPA030490: AB_10601922" "unprognostic (5.93e-2)" "unprognostic (2.49e-3)" "unprognostic (2.98e-1)" "unprognostic (3.99e-3)" "unprognostic (2.56e-1)" "unprognostic (2.85e-3)" "unprognostic (5.44e-2)" "unprognostic (1.24e-2)" "unprognostic (6.75e-2)" "unprognostic (8.78e-2)" "unprognostic (3.67e-2)" "unprognostic (1.47e-1)" "prognostic favorable (4.26e-4)" "unprognostic (3.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (3.47e-2)" 19.9 8.2 8.2 13.8 15.0 40.3 15.0 19.3 9.1 8.9 0.0 11.4 4.6 16.9 5.9 9.7 10.0 11.8 10.1 8.3 13.4 7.9 7.1 15.2 7.7 20.2 17.0 14.2 5.1 3.0 4.9 5.8 20.9 8.2 5.3 4.7 7.4 7.4 4.9 6.8 10.3 20.9 12.1 10.3 9.1 6.8 17.4 14.3 8.8 7.4 7.3 9.8 9.8 20.3 8.8 6.1 16.3 1.1 5.6 14.4 3.4 10.0 8.0 15.3 6.7 0.1 7.1 0.1 6.3 20.6 26.5 21.5 13.9 46.2 8.2 6.0 0.8 0.2 18.5 3.5 9.7 4.6 6.7 19.3 15.3 10.7 35.0 22.0 18.1 4.6 0.0 8.2 11.8 0.2 5.6 1.7 9.7 0.9 3.0 2.4 4.3 6.4 3.7 6.8 25.0 30.5 8.6 12.0 7.8 13.0 2.0 6.9 35.9 30.3 14.5 12.9 12.0 6.2 4.5 0.0 26.7 3.8 6.1 28.9 9.4 12.3 1.6 12.1 0.6 5.7 8.4 1.6 5.3 7.7 14.3 9.9 40.8 22.9 22.7 2.4 7.7 6.1 8.2 15.0 19.3 9.1 8.3 13.4 20.2 17.0 20.9 12.1 17.4 20.3 95.2 41.7 6.7 74.4 15.8 21.9 23.1 35.0 6.2 9.0 9.9 11.4 17.6 14.3 15.1 9.2 12.5 0.5 6.9 0.4 1.9 22.7 10.2 13.9 33.7 65.8 6.0 2.5 46.4 51.5 0.8 22.0 11.7 17.3 12.0 3.6 79.9 14.7 15.6 11.8 31.1 2.6 34.6 50.0 22.9 5.2 13.7 37.6 3.6 61.8 28.3 7.1 8.2 68.9 160.5 79.9 1.4 10.1 4.3 9.2 14.1 4.3 9.8 8.7 46.0 38.6 42.0 0.8 14.8 8.1 15.3 1.1 7.6 7.9 4.3 9.3 KLHL18 "FLJ13703, KIAA0795" ENSG00000114648 "Kelch like family member 18" O94889 3 47282917-47346816 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035027, HPA035028" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Nuclear bodies" "HPA035027: AB_10602340, HPA035028: AB_10669899" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (3.82e-2)" "unprognostic (2.26e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.22e-1)" "unprognostic (9.01e-2)" "unprognostic (3.05e-1)" "unprognostic (9.60e-2)" "unprognostic (3.23e-3)" "unprognostic (2.88e-3)" "unprognostic (3.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.07e-1)" "unprognostic (4.67e-1)" 5.9 6.2 6.5 6.2 6.9 15.9 4.6 5.9 7.7 5.7 3.9 5.8 4.4 5.3 5.1 8.7 4.6 5.4 6.2 6.8 6.3 6.1 3.7 6.2 6.9 4.9 6.0 3.9 5.5 7.2 6.0 5.5 5.1 5.1 4.6 20.2 4.4 6.2 6.7 13.8 5.6 6.6 5.5 8.8 4.9 6.3 6.7 5.1 7.0 5.6 7.5 6.7 6.7 6.3 11.6 14.6 11.1 16.5 12.0 8.6 7.9 15.6 8.1 15.5 12.6 15.6 7.0 22.6 8.6 13.1 14.2 7.0 33.7 16.5 15.9 18.0 11.3 33.3 20.9 14.3 12.3 17.9 14.7 10.0 12.5 22.4 20.8 8.7 17.5 12.1 41.0 9.2 12.6 9.6 13.7 10.3 20.4 9.4 29.2 9.4 7.3 13.2 14.6 21.6 7.6 10.1 10.9 13.2 7.9 11.3 7.8 9.7 18.4 14.3 14.8 16.6 19.9 10.3 21.9 19.5 9.2 20.5 15.4 6.1 12.1 3.7 2.0 10.7 2.9 3.8 1.6 3.9 7.8 2.4 1.3 2.0 4.9 1.3 18.6 2.0 1.7 5.7 6.5 6.9 5.9 7.7 6.8 6.3 4.9 6.0 5.1 5.5 6.7 6.3 19.6 12.8 13.7 13.1 24.4 11.3 10.6 8.1 12.0 65.2 17.4 13.0 62.1 4.3 7.5 3.7 20.9 10.6 26.1 15.2 21.5 15.5 3.0 15.5 24.8 16.1 9.5 21.7 24.2 14.8 11.9 9.3 12.2 27.5 36.1 11.0 14.3 19.7 29.6 13.5 23.0 11.1 4.1 28.8 14.9 3.5 5.9 26.7 0.0 18.7 22.4 13.9 8.2 15.1 17.4 17.7 10.6 8.2 12.0 9.3 9.8 28.2 6.3 54.2 6.6 19.5 13.5 13.9 14.8 14.8 21.0 14.1 20.8 15.4 10.3 13.0 KLHL25 "ENC-2, ENC2, FLJ12587" ENSG00000183655 "Kelch like family member 25" Q9H0H3 15 85759326-85794925 "Predicted intracellular proteins" "Translation regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 3.8" "Group enriched" "Detected in many" 4 "monocytes: 3.8;NK-cells: 2.5;T-cells: 1.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 29.1;hippocampal formation: 16.3" HPA023450 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA023450: AB_1852583" "unprognostic (1.18e-1)" "unprognostic (1.06e-2)" "unprognostic (2.78e-2)" "unprognostic (1.99e-2)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (2.94e-2)" "unprognostic (8.98e-2)" "unprognostic (6.60e-2)" "unprognostic (9.29e-3)" "unprognostic (4.25e-2)" "unprognostic (5.18e-2)" "unprognostic (2.22e-2)" "unprognostic (3.57e-2)" "unprognostic (1.80e-1)" "unprognostic (2.08e-1)" "unprognostic (2.66e-2)" 6.5 2.4 5.6 2.6 7.6 0.5 5.4 5.8 7.5 4.3 4.3 3.8 4.7 6.6 3.1 5.7 4.0 2.2 3.9 6.0 7.6 3.7 15.1 4.3 1.9 5.4 8.2 3.3 1.6 2.2 3.6 1.1 6.9 4.6 1.1 0.8 3.6 3.1 6.5 9.3 3.4 2.8 4.7 1.6 5.0 10.5 7.6 2.0 2.4 3.0 1.3 3.7 5.0 6.7 2.7 8.1 11.6 5.7 2.3 1.2 6.0 3.4 1.6 4.6 3.5 10.9 4.4 1.7 1.7 2.8 2.9 6.6 12.5 6.4 1.0 1.7 5.8 0.5 3.5 8.4 2.7 0.5 2.0 2.4 2.1 4.5 1.5 2.0 2.5 5.8 0.7 1.5 2.0 5.0 4.3 2.6 10.5 4.6 4.2 8.7 6.9 2.8 1.7 5.6 16.1 11.1 4.9 5.6 2.2 4.7 10.2 0.6 2.1 4.9 8.9 3.2 6.2 1.6 3.7 1.7 2.2 3.0 2.8 0.0 0.1 0.2 1.0 1.2 0.5 0.0 1.0 0.7 0.2 0.2 1.7 1.1 0.0 2.5 3.8 0.6 0.9 0.5 5.6 7.6 5.8 7.5 6.0 7.6 5.4 8.2 6.9 4.7 7.6 6.7 0.8 0.0 1.9 3.6 1.2 2.7 4.0 2.1 0.0 3.3 4.0 2.8 4.3 1.5 1.5 0.0 0.0 1.0 3.6 6.3 1.9 2.3 13.0 3.0 3.6 1.8 10.7 0.0 7.7 2.7 1.5 2.4 8.6 3.2 0.0 2.0 2.2 12.4 0.8 13.5 4.1 7.6 4.1 1.3 2.7 4.6 0.9 1.4 7.2 1.0 0.6 2.7 2.1 6.0 0.9 5.3 3.1 1.5 1.3 2.7 2.7 2.1 2.1 1.1 6.6 2.9 2.9 3.3 4.1 4.4 4.7 1.8 4.0 1.4 5.2 4.3 KLHL32 "BKLHD5, KIAA1900" ENSG00000186231 "Kelch like family member 32" Q96NJ5 6 96924620-97140754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 65.2" "Cell type enhanced" "Detected in many" "Astrocytes: 143.7;Excitatory neurons: 168.8;Inhibitory neurons: 143.9;Oligodendrocyte precursor cells: 197.5;Oligodendrocytes: 724.3" "Cancer enhanced" "Detected in some" "glioma: 2.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "B-cells: 1.0;T-cells: 2.6" "Cell line enhanced" "Detected in some" "Daudi: 3.3;HDLM-2: 4.5;RPMI-8226: 2.1;SCLC-21H: 1.8;U-266/70: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039150 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039150: AB_2676367" "unprognostic (1.75e-1)" "unprognostic (7.99e-2)" "unprognostic (6.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.67e-1)" "unprognostic (5.22e-2)" "unprognostic (5.00e-1)" "unprognostic (3.12e-3)" "unprognostic (5.88e-3)" "unprognostic (1.01e-1)" "unprognostic (1.51e-5)" "unprognostic (5.82e-2)" "unprognostic (6.04e-2)" "unprognostic (7.01e-2)" "unprognostic (1.86e-2)" "unprognostic (7.48e-2)" "unprognostic (4.49e-4)" 0.2 0.9 19.6 0.4 40.7 0.1 0.3 24.7 33.3 0.3 1.7 0.6 0.8 0.2 0.4 0.0 6.4 0.3 0.7 21.6 25.9 1.9 0.6 0.7 0.4 31.2 28.2 0.9 1.3 0.7 1.2 0.0 29.9 0.2 0.9 2.5 0.5 0.2 1.2 0.1 1.1 0.1 25.3 0.3 0.5 1.6 29.1 0.7 0.7 0.3 0.4 0.1 0.1 65.2 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 3.3 0.1 0.0 0.0 0.1 0.3 0.1 0.0 4.5 0.7 0.2 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 1.6 0.0 0.0 0.8 0.2 0.2 0.1 0.1 0.1 0.0 2.1 0.0 0.0 1.8 0.6 0.0 0.0 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.3 0.4 1.3 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.9 1.0 1.7 0.6 0.0 0.7 1.9 2.6 0.0 0.4 0.0 0.0 1.2 0.8 19.6 40.7 24.7 33.3 21.6 25.9 31.2 28.2 29.9 25.3 29.1 65.2 0.2 3.2 0.0 143.7 1.1 0.0 0.3 0.1 0.0 2.5 0.4 0.5 2.6 0.0 0.1 5.5 0.0 0.1 0.2 0.3 3.9 0.2 6.9 7.5 0.1 0.0 11.3 0.0 168.8 0.2 0.0 0.3 1.5 0.2 0.0 3.2 0.4 1.3 0.1 18.5 143.9 4.1 0.0 0.0 0.0 3.3 0.0 0.1 0.0 13.1 0.0 1.1 0.0 197.5 724.3 0.0 0.1 0.0 0.5 0.2 0.5 2.4 15.3 1.1 0.0 0.2 0.1 0.8 1.8 0.0 0.0 0.0 0.7 1.1 0.5 0.0 KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 324.2;skin 1: 239.8;vagina: 186.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 152.1;Club cells: 217.9;Late spermatids: 339.0;Prostatic glandular cells: 234.8;Squamous epithelial cells: 176.4;Suprabasal keratinocytes: 217.1;Urothelial cells: 186.1" "Cancer enhanced" "Detected in many" "prostate cancer: 53.3" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;HaCaT: 41.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026340 Approved "Secreted in other tissues" NA NA 1800000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" 28.4 0.2 0.0 0.4 0.0 0.0 17.1 0.9 0.1 109.8 44.5 1.9 0.7 7.2 2.6 324.2 34.2 59.3 2.0 1.7 0.0 0.3 0.8 18.9 0.0 0.2 0.1 1.6 89.1 0.0 8.8 0.0 0.3 64.9 0.6 0.7 169.5 4.2 1.9 239.8 1.4 0.3 0.0 0.1 113.3 14.4 0.6 2.5 0.4 0.3 27.2 1.4 186.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.4 0.1 13.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.7 0.0 0.2 0.1 0.3 0.0 0.6 0.0 0.2 86.6 10.4 0.0 0.4 106.9 152.1 131.6 13.1 0.2 33.4 35.3 0.8 88.6 217.9 0.0 0.0 0.0 0.0 0.1 0.0 9.2 111.6 4.7 1.1 3.8 20.3 0.0 0.0 130.2 0.0 9.1 91.3 15.6 1.3 0.0 0.0 0.0 0.3 0.0 0.0 10.7 118.0 0.0 11.4 339.0 2.8 1.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 79.4 0.0 0.4 0.5 234.8 0.1 0.0 26.9 1.3 0.0 0.2 7.9 2.1 2.5 176.4 217.1 0.0 1.7 0.0 0.4 186.1 KLK5 "KLK-L2, SCTE" ENSG00000167754 "Kallikrein related peptidase 5" Q9Y337 19 50943303-50953093 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 202.7" "Group enriched" "Detected in some" 4 "Early spermatids: 85.4;Late spermatids: 193.2" "Group enriched" "Detected in many" 5 "head and neck cancer: 73.1;melanoma: 32.1;ovarian cancer: 112.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 41 "A-431: 485.1;HaCaT: 455.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014343, CAB025503, CAB026341, HPA073512" Enhanced "Secreted in other tissues" NA NA 2500000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "CAB025503: , CAB026341: , HPA014343: AB_1852603, HPA073512: " "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.30e-4)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.04e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" "unprognostic (2.21e-1)" "unprognostic (2.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.16e-3)" "prognostic unfavorable (3.85e-6)" 4.6 0.0 1.1 0.0 1.1 0.0 30.2 0.4 2.6 15.6 0.6 0.0 0.1 0.1 0.0 23.0 0.5 0.0 0.2 1.1 0.8 0.5 0.1 6.1 0.0 1.0 1.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 23.6 0.0 1.1 202.7 0.0 0.0 0.5 0.3 0.0 14.2 1.6 0.1 0.1 0.0 0.6 0.0 13.5 0.7 485.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.1 455.4 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.3 0.0 0.0 1.1 0.0 1.5 0.1 0.4 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.4 2.6 1.1 0.8 1.0 1.0 1.0 0.5 1.6 0.7 0.2 16.0 0.0 0.0 0.0 26.8 1.8 2.4 12.0 0.0 33.0 27.2 0.3 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 85.4 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 193.2 1.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 1.6 0.8 2.8 10.9 0.0 0.3 0.0 0.0 0.1 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 118.0;skin 1: 87.1;vagina: 47.2" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 66.0;Suprabasal keratinocytes: 180.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 88.3;CAPAN-2: 112.2;HaCaT: 83.5" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 3200000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" 5.7 0.0 0.1 0.0 0.0 0.0 8.4 0.8 0.7 24.7 0.2 0.0 0.0 0.9 0.4 118.0 13.2 0.1 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.7 0.2 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 17.1 0.1 0.7 87.1 0.0 0.1 0.0 0.2 0.1 1.2 0.2 1.1 0.5 0.0 9.6 0.0 47.2 0.5 88.3 0.0 0.0 0.6 0.0 0.0 12.3 0.0 0.0 0.0 0.0 1.7 112.2 0.0 2.2 0.0 0.1 83.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 10.3 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.7 0.0 0.0 0.7 0.2 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.3 66.0 0.0 0.4 14.8 0.0 13.0 15.6 0.1 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.7 11.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 5.0 1.8 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 2.8 6.2 21.1 180.1 0.0 0.2 0.0 0.2 0.1 KLK9 KLK-L3 ENSG00000213022 "Kallikrein related peptidase 9" Q9UKQ9 19 51002508-51009634 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 11.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.0" CAB025049 Enhanced "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "CAB025049: " "unprognostic (3.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLRF2 NKp65 ENSG00000256797 "Killer cell lectin like receptor F2" D3W0D1 12 9881489-9895833 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "skin 1: 11.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "NK-cell: 3.1;plasmacytoid DC: 3.2" "Group enriched" "Detected in many" 32 "dendritic cells: 3.2;NK-cells: 3.1" "Cell line enriched" "Detected in single" 47 "U-937: 31.5" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (5.57e-2)" "unprognostic (3.40e-5)" "unprognostic (9.03e-2)" "unprognostic (3.16e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 11.9 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 KMT2E "HDCMC04P, MLL5" ENSG00000005483 "Lysine methyltransferase 2E (inactive)" Q8IZD2 7 105014190-105115019 "Disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Growth arrest, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042866, HPA056125" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies" "HPA042866: , HPA056125: AB_2683044" "unprognostic (1.05e-1)" "unprognostic (6.33e-2)" "unprognostic (6.49e-2)" "unprognostic (4.34e-1)" "unprognostic (1.94e-1)" "unprognostic (4.77e-2)" "unprognostic (2.20e-1)" "unprognostic (3.98e-3)" "unprognostic (2.03e-2)" "unprognostic (3.16e-2)" "unprognostic (3.53e-2)" "unprognostic (6.45e-2)" "prognostic unfavorable (3.80e-5)" "unprognostic (1.68e-1)" "unprognostic (1.53e-1)" "unprognostic (3.57e-2)" "unprognostic (1.06e-1)" 23.0 16.4 17.6 28.8 23.6 69.9 22.5 53.6 26.1 28.9 11.6 29.0 22.7 33.4 22.1 22.7 24.8 24.5 21.1 16.9 25.9 18.7 16.4 27.9 31.4 19.0 19.2 43.8 22.8 23.1 11.5 26.8 17.7 24.9 28.5 40.5 25.5 23.0 15.0 30.3 22.3 26.8 14.4 33.4 26.7 18.6 17.1 35.6 27.4 22.9 33.0 27.9 14.3 34.4 35.7 24.8 49.3 43.5 29.3 34.5 12.3 24.3 38.2 21.0 25.5 19.0 30.1 28.8 24.7 30.0 27.7 26.2 27.1 25.7 35.0 45.8 17.4 27.0 31.6 19.2 28.1 39.7 34.8 24.2 23.3 28.6 30.6 38.6 40.2 32.3 39.9 76.9 28.7 26.5 62.1 35.0 17.9 19.1 19.1 53.4 30.3 33.5 23.0 34.5 28.8 36.1 35.7 32.3 20.2 32.8 13.6 23.5 47.2 50.0 33.1 57.5 26.4 61.6 50.8 63.5 34.3 29.5 36.3 246.8 73.2 173.1 118.3 56.2 114.6 153.9 109.7 103.0 53.8 152.0 106.0 100.0 290.3 89.9 94.4 103.2 101.5 71.7 17.6 23.6 53.6 26.1 16.9 25.9 19.0 19.2 17.7 14.4 17.1 34.4 169.3 141.1 158.4 108.4 283.5 146.6 115.5 119.2 118.4 236.4 93.4 81.5 102.9 85.8 124.6 115.8 252.3 40.5 278.0 138.0 35.2 82.2 27.0 77.8 89.3 205.6 100.0 90.5 160.2 68.1 50.4 128.8 91.7 112.4 247.9 78.2 119.2 33.6 60.4 185.1 148.9 96.4 89.5 91.8 348.4 27.3 141.1 152.2 140.5 148.9 147.5 104.1 255.4 189.0 236.2 80.7 102.9 131.7 223.1 149.7 82.6 32.4 78.3 297.5 124.9 136.7 168.3 100.0 76.4 86.1 134.7 65.3 278.3 58.2 115.4 159.9 KMT5A "PR-Set7, SET07, SET8, SETD8" ENSG00000183955 "Lysine methyltransferase 5A" Q9NQR1 12 123383773-123409353 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064495 Supported Nucleoplasm,Cytosol NA Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA064495: AB_2685273" "unprognostic (5.62e-2)" "unprognostic (4.45e-2)" "unprognostic (3.90e-1)" "unprognostic (3.04e-1)" "unprognostic (2.20e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.21e-7)" "unprognostic (3.88e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-2)" "unprognostic (6.13e-2)" "unprognostic (3.44e-1)" "unprognostic (4.75e-3)" "unprognostic (4.27e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.06e-1)" 13.7 10.1 22.6 15.3 22.1 39.2 13.1 20.8 23.2 22.2 18.7 17.7 12.8 21.3 12.9 40.7 21.7 13.6 17.0 22.2 20.6 13.7 14.0 15.5 15.4 22.4 22.7 12.0 19.7 11.4 10.7 16.5 22.9 30.2 14.4 11.7 24.0 19.7 24.4 28.1 15.6 16.7 21.4 16.8 16.9 7.9 23.3 17.9 25.7 15.3 16.6 16.6 25.7 23.9 37.3 24.3 27.8 43.5 18.1 30.9 40.1 57.4 26.3 32.0 26.9 28.8 21.9 84.9 33.1 37.5 11.7 35.8 41.6 21.7 33.3 39.3 45.0 68.8 26.4 15.2 26.5 54.8 18.8 15.1 27.1 34.7 32.8 30.2 26.2 36.4 136.8 38.1 27.5 29.9 58.1 84.9 13.8 34.6 29.0 70.4 22.1 24.1 22.8 43.4 37.9 30.9 51.3 28.3 28.6 23.6 39.6 75.3 32.4 35.2 26.0 42.3 42.3 23.0 25.9 75.9 24.6 29.6 29.9 2.3 1.2 4.3 1.3 2.1 2.7 1.7 1.6 2.1 1.0 1.1 0.9 1.1 1.8 2.3 2.1 2.0 1.5 0.3 22.6 22.1 20.8 23.2 22.2 20.6 22.4 22.7 22.9 21.4 23.3 23.9 34.5 12.8 14.5 0.0 12.7 0.0 17.6 0.0 20.5 20.8 32.0 27.3 0.0 7.2 6.8 27.6 6.2 15.1 22.4 10.4 7.9 9.2 10.1 46.8 43.8 20.7 4.9 62.1 0.0 9.4 16.6 14.7 15.8 41.1 2.5 21.3 30.4 19.5 17.7 3.3 0.0 22.2 0.0 16.8 0.0 3.2 16.1 19.6 0.0 0.0 3.4 28.7 7.2 0.0 0.0 13.6 9.6 42.9 15.9 24.1 14.3 13.1 11.7 17.9 6.6 23.2 19.7 9.7 10.2 38.8 0.0 14.2 14.5 18.4 12.7 22.5 KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.3;lymphoid tissue: 7.4;testis: 16.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.5;Extravillous trophoblasts: 11.3;Granulosa cells: 22.8;Hofbauer cells: 7.1;Proximal tubular cells: 11.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA026624: AB_10601696, HPA049647: AB_2680840" "unprognostic (5.35e-2)" "unprognostic (1.01e-1)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.59e-2)" "unprognostic (5.66e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.06e-2)" "unprognostic (1.43e-1)" "unprognostic (3.20e-4)" "unprognostic (2.22e-2)" "unprognostic (1.93e-12)" "unprognostic (3.07e-2)" "unprognostic (3.08e-1)" "unprognostic (8.45e-2)" "unprognostic (7.36e-2)" 0.2 0.1 0.1 1.9 0.0 5.3 0.3 0.2 0.2 0.2 0.2 1.3 1.6 0.3 0.2 1.0 0.1 0.3 0.1 0.1 0.1 0.5 0.7 0.4 3.6 0.1 0.3 0.0 0.0 0.3 0.0 1.3 0.1 0.1 1.4 0.2 0.2 0.0 0.0 0.8 1.7 0.7 0.0 0.6 0.9 16.9 0.3 7.4 0.3 0.1 3.4 0.5 0.2 0.1 19.1 9.3 18.0 13.8 0.5 2.6 8.6 20.5 8.1 16.0 13.1 11.6 7.2 11.9 6.1 9.3 12.0 21.9 17.6 9.7 16.3 21.4 5.0 35.5 15.5 3.9 0.0 26.2 17.8 0.5 0.4 10.8 6.4 2.1 13.8 20.9 22.9 19.2 18.3 6.1 23.5 6.1 9.4 11.3 9.5 21.2 25.8 5.9 2.6 15.6 15.9 7.7 17.7 10.6 2.1 5.9 11.1 9.0 13.1 18.7 16.3 21.9 11.7 7.5 27.9 22.3 7.6 18.5 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.3 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.8 1.8 0.0 8.5 2.6 0.0 1.9 0.2 0.0 3.5 3.5 1.9 0.0 0.0 0.0 0.6 11.3 4.2 0.0 2.9 0.0 22.8 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.1 0.0 0.0 11.5 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 3.7 1.9 1.7 0.0 0.0 KNSTRN "C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1" ENSG00000128944 "Kinetochore localized astrin (SPAG5) binding protein" Q9Y448 15 40382721-40394246 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.6;thyroid gland: 53.1" "Cell type enhanced" "Detected in many" "Early spermatids: 328.2;Late spermatids: 600.1;Spermatocytes: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042027 Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Mitotic spindle, Centriolar satellite" "Plasma membrane" "HPA042027: AB_10797378" "unprognostic (2.35e-3)" "unprognostic (6.83e-2)" "unprognostic (3.01e-1)" "unprognostic (5.23e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-2)" "unprognostic (1.54e-3)" "unprognostic (2.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.88e-9)" "unprognostic (1.70e-1)" "unprognostic (1.58e-1)" "unprognostic (2.67e-1)" "unprognostic (1.52e-2)" 8.0 6.2 6.3 8.1 7.1 14.1 14.3 7.7 8.6 5.1 4.5 7.9 9.2 6.4 12.3 9.1 5.7 4.4 7.4 7.2 6.2 7.2 12.0 5.8 14.5 6.2 6.2 5.1 5.0 8.4 5.6 10.7 6.5 6.8 10.4 9.0 10.3 7.2 12.2 6.7 6.2 10.2 5.9 7.1 10.2 63.6 6.1 25.6 53.1 12.4 16.1 5.6 5.6 7.7 103.4 47.5 92.7 61.0 20.1 30.9 48.1 69.9 54.0 141.0 123.3 102.6 44.2 39.7 34.8 47.3 112.1 115.7 100.0 64.8 126.5 70.8 48.8 117.7 107.4 65.2 18.9 63.8 58.6 16.1 36.5 71.3 70.6 34.5 80.3 97.6 86.3 66.8 120.0 52.2 55.6 51.2 58.6 87.7 71.2 56.4 69.7 45.7 49.7 42.3 89.9 62.5 58.3 63.3 15.1 55.8 66.5 45.3 41.6 67.5 68.8 69.7 98.3 56.5 98.6 70.5 41.8 84.0 56.5 13.2 17.6 17.4 7.9 24.3 6.8 9.5 5.7 7.0 18.4 11.2 5.4 5.5 9.7 9.8 47.8 12.7 9.4 7.1 6.3 7.1 7.7 8.6 7.2 6.2 6.2 6.2 6.5 5.9 6.1 7.7 2.4 9.6 1.1 2.6 4.1 2.2 2.9 7.6 3.4 8.2 4.2 3.4 7.3 1.5 5.4 0.0 8.4 25.2 2.5 1.9 3.9 8.5 328.2 5.9 4.9 3.7 2.4 34.3 5.1 9.3 40.8 5.2 5.6 4.4 1.3 16.9 3.6 8.0 21.6 5.0 4.9 5.3 14.2 9.8 2.0 600.1 9.0 8.2 3.6 4.7 8.0 8.5 6.2 2.0 4.3 12.3 0.5 7.2 12.6 4.9 2.8 5.8 7.2 8.5 0.0 3.7 6.5 145.7 19.2 7.0 1.4 21.1 5.1 8.5 6.4 3.0 KPNA6 "FLJ11249, IPOA7, KPNA7, MGC17918" ENSG00000025800 "Karyopherin subunit alpha 6" O60684 1 32108056-32176563 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 294.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018863 Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA018863: AB_1852632" "unprognostic (8.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.95e-1)" "unprognostic (3.30e-2)" "unprognostic (8.35e-2)" "unprognostic (7.34e-2)" "prognostic unfavorable (9.28e-5)" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.51e-2)" "unprognostic (3.18e-1)" "unprognostic (5.32e-2)" "unprognostic (1.73e-2)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (1.80e-1)" "unprognostic (1.57e-2)" 14.2 15.4 12.8 11.0 13.9 20.5 13.1 12.4 15.1 15.4 12.7 17.7 8.8 17.1 12.8 18.8 14.2 8.8 22.0 13.8 17.2 13.8 15.8 15.1 11.1 15.7 16.3 13.4 13.4 24.6 14.3 16.6 18.2 13.9 13.0 17.1 13.4 14.3 39.3 18.5 12.5 17.8 12.0 12.0 14.8 20.2 14.6 12.8 13.5 23.7 14.8 15.6 15.6 14.5 32.0 24.8 21.6 28.0 32.5 28.4 25.3 25.2 29.5 36.0 34.5 27.8 33.9 26.5 29.1 45.6 21.6 26.7 33.5 38.5 45.6 27.0 18.4 27.4 36.4 22.6 28.7 30.4 21.5 28.9 35.8 44.6 42.3 30.3 38.1 20.5 27.0 23.7 34.4 17.5 24.6 17.3 50.5 20.6 18.3 24.5 31.0 21.7 31.4 28.9 20.7 17.4 45.8 27.1 25.0 52.6 19.2 15.9 44.5 33.1 22.7 43.8 36.6 16.9 20.7 20.3 36.3 27.8 32.4 3.2 7.4 7.2 7.7 9.1 7.5 5.3 6.5 6.0 6.0 6.1 7.4 7.2 4.2 3.8 9.9 6.7 7.3 5.3 12.8 13.9 12.4 15.1 13.8 17.2 15.7 16.3 18.2 12.0 14.6 14.5 27.9 41.7 41.5 33.0 36.1 63.6 36.9 37.6 22.2 48.6 44.7 26.7 32.7 37.1 32.4 29.5 58.4 45.4 42.4 29.5 17.6 36.2 294.2 41.0 44.6 40.4 46.1 52.8 62.5 31.6 41.6 35.7 25.5 49.3 13.9 31.3 36.0 77.3 30.4 52.2 58.4 36.0 24.4 36.8 44.8 65.2 34.2 29.3 24.9 30.0 41.4 29.0 47.4 40.7 54.3 46.1 26.4 40.6 24.1 56.7 25.3 33.2 48.2 44.7 32.9 53.1 36.7 78.7 56.2 31.2 85.1 135.7 31.7 31.8 35.6 59.0 KPRP C1orf45 ENSG00000203786 "Keratinocyte proline rich protein" Q5T749 1 152759561-152762052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 329.1" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 20.0" "Group enriched" "Detected in some" 22 "head and neck cancer: 6.9;melanoma: 13.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 1.9;U-2197: 1.1" "Not detected" "Not detected" "HPA031988, HPA031990" Enhanced NA NA 27000000 "Cluster 61: Skin - Cornification" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "HPA031988: AB_10671582, HPA031990: AB_2674102" "unprognostic (1.03e-1)" "unprognostic (2.67e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" 0.2 0.0 0.0 0.0 0.9 0.1 10.3 0.0 0.1 13.9 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 1.7 329.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 4.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 KREMEN2 "KRM2, MGC10791" ENSG00000131650 "Kringle containing transmembrane protein 2" Q8NCW0 16 2964216-2968383 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 4.1;skin 1: 7.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 14.1;Basal squamous epithelial cells: 23.3;Intestinal goblet cells: 14.0;Rod photoreceptor cells: 10.9;Spermatocytes: 9.7;Spermatogonia: 18.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.2;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cell line enhanced" "Detected in many" "HMC-1: 29.3;MCF7: 15.0;RPMI-8226: 28.8;T-47d: 14.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA003223 Uncertain Approved Nucleoli "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoli "HPA003223: AB_1079217" "unprognostic (8.36e-2)" "unprognostic (4.65e-1)" "unprognostic (6.24e-3)" "unprognostic (4.61e-2)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (4.02e-3)" "prognostic unfavorable (8.98e-4)" "unprognostic (3.34e-2)" "unprognostic (1.57e-2)" "unprognostic (8.03e-2)" "unprognostic (8.57e-2)" "unprognostic (7.79e-12)" "unprognostic (6.69e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-2)" "unprognostic (6.58e-3)" 0.1 0.1 0.7 0.3 0.7 0.7 0.1 0.0 0.6 1.5 0.0 0.3 0.1 0.1 0.1 2.0 0.3 0.1 0.0 1.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.0 4.1 0.4 0.0 0.3 7.7 0.6 0.0 0.0 0.2 0.2 1.7 0.0 2.1 0.0 0.0 0.8 0.0 0.5 0.1 1.8 1.1 0.4 10.2 0.0 0.0 1.5 0.6 0.0 0.0 0.0 4.2 1.5 7.8 2.1 0.0 1.1 8.6 1.3 0.7 0.0 1.1 1.2 0.5 2.9 2.6 0.0 0.6 29.3 0.2 0.0 0.0 0.1 0.9 0.0 0.8 3.3 2.9 0.0 15.0 1.8 3.5 2.9 3.0 2.2 4.7 11.8 28.8 0.1 0.3 2.9 1.8 2.0 4.7 5.2 0.4 14.9 2.8 0.2 0.9 12.2 1.0 0.7 5.3 1.3 4.7 0.4 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.7 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 1.4 14.1 0.9 0.3 23.3 0.4 1.0 0.9 0.9 0.0 0.0 0.0 6.2 0.2 0.0 1.1 0.0 0.1 0.7 0.4 0.1 0.1 0.0 0.0 0.4 2.7 1.8 0.1 0.0 0.9 4.5 0.0 0.0 0.0 0.1 0.0 0.1 14.0 0.0 0.0 0.6 0.6 0.0 0.2 3.6 0.0 0.1 0.5 0.0 0.0 0.0 0.2 1.3 0.0 0.1 2.1 0.5 0.0 0.0 10.9 0.0 0.0 0.3 9.7 18.0 1.2 5.5 0.1 0.6 0.0 0.5 0.4 KRT1 "EHK1, KRT1A" ENSG00000167768 "Keratin 1" P04264 12 52674736-52680407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skin 1: 13006.6" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 10030.4" "Group enriched" "Detected in many" 5 "head and neck cancer: 313.8;melanoma: 478.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 2.3" "Lineage enriched" "Detected in single" 23 "T-cells: 2.3" "Group enriched" "Detected in some" 14 "HaCaT: 94.9;hTCEpi: 39.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002153, HPA017917, HPA062908" Enhanced NA NA 35000000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB002153: AB_563790, HPA017917: AB_1852192, HPA062908: AB_2684901" "unprognostic (8.05e-2)" "unprognostic (8.49e-3)" "unprognostic (5.06e-3)" "unprognostic (6.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (3.24e-1)" "unprognostic (1.30e-1)" "unprognostic (2.16e-1)" "unprognostic (9.24e-2)" "unprognostic (6.63e-2)" "unprognostic (3.23e-4)" "unprognostic (1.58e-1)" "unprognostic (3.40e-2)" "unprognostic (1.36e-1)" "unprognostic (1.09e-2)" 10.3 1.4 0.0 0.1 0.0 7.7 464.1 0.0 0.1 473.6 0.0 2.6 0.2 1.3 0.4 30.8 0.4 0.3 4.5 0.0 0.0 1.2 3.5 2.6 0.0 0.0 0.0 1.4 3.7 0.0 1.4 1.6 0.0 1.5 0.1 0.0 270.2 0.1 47.8 13006.6 2.0 0.2 0.0 1.6 2.1 1.9 0.0 76.8 2.0 0.8 0.5 0.9 1257.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.7 0.0 39.3 0.0 0.0 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1681.6 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 22.3 0.0 0.0 0.0 17.4 0.0 0.0 234.7 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 267.0 0.0 0.0 0.3 265.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 10.5 0.0 0.0 1.1 10030.4 0.0 7.8 0.0 0.3 0.4 KRT10 "CK10, K10, KPP" ENSG00000186395 "Keratin 10" P13645 17 40818117-40822614 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "skin 1: 15851.5" "Cell type enriched" "Detected in all" 5 "Suprabasal keratinocytes: 12515.3" "Group enriched" "Detected in all" 4 "head and neck cancer: 310.0;melanoma: 562.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "hTCEpi: 718.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000132, HPA012014" Enhanced "Secreted in other tissues" NA NA 18000000000 "Cluster 37: B-cells - Transcription" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB000132: , HPA012014: AB_1852195" "unprognostic (3.07e-1)" "unprognostic (5.19e-2)" "unprognostic (1.71e-1)" "unprognostic (1.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.60e-1)" "unprognostic (3.02e-2)" "unprognostic (1.29e-2)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (1.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (9.32e-5)" "unprognostic (1.64e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-2)" "unprognostic (8.10e-2)" 66.1 47.9 9.4 7.6 9.8 13.4 432.0 9.9 14.9 548.0 10.4 45.2 7.9 55.0 5.5 78.6 45.5 2.2 95.7 9.9 9.8 67.2 64.5 39.7 6.2 9.8 9.7 52.3 69.1 8.2 77.2 3.8 9.8 60.0 3.4 6.9 163.9 5.5 123.1 15851.5 48.2 4.0 9.8 56.8 58.0 64.9 9.8 44.0 53.5 5.8 13.7 48.5 1106.2 10.4 30.3 31.2 11.0 12.2 14.4 11.5 10.4 29.9 16.5 11.4 10.6 11.2 11.7 8.7 42.0 13.1 16.2 158.5 5.4 11.3 13.4 20.1 27.0 9.2 44.7 19.4 16.4 17.1 24.9 10.1 718.0 9.0 17.3 15.0 7.4 12.3 102.1 16.0 12.2 17.3 25.5 16.2 14.6 23.1 19.1 17.8 16.7 17.7 12.3 26.3 8.9 11.1 19.9 46.0 39.0 17.3 35.5 24.3 9.3 17.6 29.5 22.5 34.4 0.4 19.8 22.4 24.5 10.4 23.4 12.8 2.6 11.1 4.8 2.3 5.4 11.2 5.4 6.8 4.1 5.6 5.8 5.9 0.8 6.9 3.2 8.1 5.5 1.9 9.4 9.8 9.9 14.9 9.9 9.8 9.8 9.7 9.8 9.8 9.8 10.4 197.8 35.3 40.0 19.2 187.5 2239.7 320.6 370.2 255.6 47.0 304.4 328.2 194.2 174.5 197.2 112.2 20.9 117.4 163.2 138.9 305.2 232.5 150.4 174.3 172.2 170.0 181.1 87.7 19.1 376.9 295.7 204.5 126.9 164.5 74.3 87.0 159.5 237.6 105.0 21.9 16.3 237.6 195.3 90.3 350.7 65.6 216.6 116.8 393.1 20.6 100.1 221.4 162.7 17.6 35.0 236.0 149.8 174.9 311.6 342.0 155.3 233.2 116.8 68.6 105.2 141.0 167.7 345.1 121.2 295.0 12515.3 160.1 164.3 131.4 173.1 515.6 KRT12 K12 ENSG00000187242 "Keratin 12" Q99456 17 40861303-40867223 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 1.0" "Group enriched" "Detected in some" 5 "Distal enterocytes: 3.9;Paneth cells: 12.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055217, HPA055835" Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055217: AB_2682742, HPA055835: AB_2682935" "unprognostic (1.89e-1)" "unprognostic (2.40e-2)" "unprognostic (1.01e-1)" "unprognostic (4.82e-1)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.74e-2)" "unprognostic (5.52e-2)" "unprognostic (9.41e-3)" "unprognostic (3.49e-1)" "unprognostic (1.73e-1)" "unprognostic (3.94e-3)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (2.60e-4)" "unprognostic (6.31e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 35588.3;Suprabasal keratinocytes: 11677.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4065.2;HBEC3-KT: 2003.9;hTCEpi: 2448.6;hTERT-HME1: 794.2;U-2197: 696.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" 15.8 1.2 0.0 0.0 0.0 2.7 332.7 0.0 0.0 412.0 0.0 1.7 0.0 0.9 0.0 1304.2 1.7 0.0 3.5 0.0 0.0 0.8 2.5 1.7 0.0 0.0 0.0 1.3 2.9 0.0 4.3 2.2 0.1 29.1 0.0 0.0 702.1 3.8 15.9 6940.5 2.1 0.1 0.0 0.9 1.7 1.5 0.0 186.7 2.3 0.0 262.3 0.7 846.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.0 4065.2 0.0 2003.9 0.2 0.0 0.0 0.1 1.6 0.0 0.1 0.2 2.5 0.1 2448.6 3.0 794.2 0.0 0.1 0.0 0.5 3.6 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.0 0.3 9.1 1.7 696.0 0.0 0.9 0.0 0.0 3.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.5 35588.3 1072.7 181.5 2407.4 0.0 103.5 740.9 0.3 0.0 6.0 0.0 0.0 17.9 3.2 7.3 0.0 0.1 0.0 0.1 0.0 129.0 0.0 0.0 0.0 0.0 127.0 116.5 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.4 0.0 0.0 1833.4 0.0 0.0 9.3 1990.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.5 0.0 9.9 702.0 96.8 0.0 2.3 0.0 0.0 0.0 96.3 0.0 0.1 83.2 11677.1 2.5 62.1 0.1 2.3 100.0 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KRT18 ENSG00000111057 "Keratin 18" P05783 12 52948871-52952906 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 3698.8;Ductal cells: 6583.8;Exocrine glandular cells: 4826.1;Extravillous trophoblasts: 5496.7;Pancreatic endocrine cells: 6071.5;Syncytiotrophoblasts: 7643.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 76.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 76.7" "Cell line enhanced" "Detected in many" "A549: 5639.4;BEWO: 3818.0;CACO-2: 6249.4;CAPAN-2: 4576.4;MCF7: 8470.0;SK-BR-3: 4583.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 12.1" "CAB000008, CAB000030, HPA001605" Enhanced Supported Cytosol NA NA 140000000 "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" Cytosol "CAB000008: , CAB000030: , HPA001605: AB_2666381" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.25e-1)" "unprognostic (7.26e-3)" "unprognostic (4.09e-3)" "prognostic unfavorable (5.06e-4)" "unprognostic (8.81e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (3.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.19e-1)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" 170.3 29.0 2.6 77.5 1.4 1.5 209.8 5.3 1.6 243.5 34.8 424.1 324.3 27.8 226.0 118.4 193.5 180.6 38.3 2.2 6.9 247.2 519.5 177.8 8.6 26.1 4.3 16.4 570.2 79.5 251.9 474.5 30.3 183.3 492.3 0.6 323.4 129.5 2.1 44.5 370.7 23.4 2.5 28.5 289.9 8.3 13.9 10.3 244.1 1.4 27.8 199.7 62.2 2.5 2065.1 5639.4 1.1 7.9 0.7 1.1 3818.0 313.3 349.5 368.4 104.6 6249.4 4576.4 1.4 839.8 318.4 196.5 487.2 79.1 2228.5 217.9 2.6 138.2 19.4 865.7 1743.9 942.1 0.6 1.3 13.6 202.9 323.8 437.1 1046.9 399.0 3.4 511.4 0.2 0.3 8470.0 3.8 37.3 471.0 2740.1 457.9 3.0 0.3 236.1 1803.3 1144.9 65.6 3.7 512.7 4583.8 18.8 2696.0 2446.8 6.6 137.9 5.0 441.8 6.9 68.3 1.1 7.3 4.3 0.9 1.2 36.4 76.7 0.3 2.4 0.6 0.2 2.2 4.6 4.5 1.2 2.2 7.4 11.1 4.1 3.2 2.5 0.0 0.1 0.4 2.9 2.6 1.4 5.3 1.6 2.2 6.9 26.1 4.3 30.3 2.5 13.9 2.5 14.4 862.2 286.4 0.3 29.8 14.8 1605.7 912.1 447.3 0.1 814.6 615.6 5.3 1252.5 877.3 623.5 0.0 3698.8 14.2 1942.9 275.9 6583.8 1.0 462.3 60.3 77.8 642.3 15.4 0.0 4826.1 5496.7 203.5 971.5 742.4 48.9 51.2 57.1 610.9 308.3 1.7 0.0 2492.6 1969.3 9.8 13.8 3.8 10.5 28.3 208.1 1.0 41.5 6.2 0.0 0.0 0.0 6071.5 2164.1 0.0 13.7 1205.1 1912.3 718.5 500.8 0.6 0.0 0.6 298.6 2.7 26.0 395.7 6.7 7643.5 38.1 45.0 1635.0 1512.1 KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 889.0;salivary gland: 810.7;urinary bladder: 781.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 7444.0;Club cells: 5055.9;Ductal cells: 4717.9;Extravillous trophoblasts: 6919.3;Pancreatic endocrine cells: 7374.9;Proximal enterocytes: 8623.3;Urothelial cells: 5959.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 1945.3;HBEC3-KT: 2945.0;MCF7: 2220.9;RT4: 3146.7;SK-BR-3: 5446.1;T-47d: 3674.2" "Not detected" "Not detected" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 300000000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Intermediate filaments" "CAB000031: AB_2234418, HPA002465: AB_1079179" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.82e-5)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (3.52e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.35e-2)" 89.3 18.7 2.0 61.7 2.4 0.3 403.3 7.9 2.5 250.0 1.6 525.7 348.3 57.9 72.0 889.0 176.1 298.6 13.5 1.5 1.7 141.8 7.7 204.1 0.4 1.6 2.9 74.4 48.8 14.3 15.6 175.1 2.2 208.3 359.2 0.1 810.7 194.2 1.3 141.9 776.1 46.5 1.4 1.2 631.5 3.4 1.8 127.8 28.3 1.6 98.3 781.4 317.0 1.8 2.6 343.4 0.0 6.3 0.7 1.8 1169.3 412.1 0.5 12.8 2.9 992.6 1945.3 0.4 393.3 199.0 1.5 1044.6 0.1 2945.0 2.5 0.8 10.4 0.2 213.4 692.3 30.3 0.0 82.0 0.7 524.9 9.0 0.4 0.2 26.2 0.0 148.4 2.5 0.1 2220.9 5.9 3.0 18.5 1323.5 492.7 2.9 0.1 5.8 1335.4 3146.7 40.0 1.7 3.3 5446.1 0.1 266.5 3674.2 0.3 1.7 3.6 6.1 7.7 0.7 1.1 0.8 2.0 1.5 0.3 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.0 2.4 7.9 2.5 1.5 1.7 1.6 2.9 2.2 1.4 1.8 1.8 10.5 673.1 185.5 0.0 17.8 5.2 4317.3 7444.0 1715.8 0.0 1393.0 867.5 2.9 662.0 5055.9 892.0 0.0 1160.8 20.5 3599.6 1.9 4717.9 0.1 737.2 102.8 41.9 362.5 0.0 0.1 2589.9 6919.3 171.8 1571.4 1010.7 94.6 1.0 1.1 0.7 179.0 0.0 0.1 1382.4 2720.0 2.6 2.5 2.6 37.9 25.5 190.3 1.0 30.0 0.8 0.0 0.0 0.0 7374.9 3399.6 88.8 19.9 2228.8 8623.3 26.7 1954.3 0.0 0.0 0.0 240.0 1.1 1.6 1302.6 1.1 2127.5 36.1 4.8 1619.0 5959.8 KRT2 "KRT2A, KRTE" ENSG00000172867 "Keratin 2" P35908 12 52644558-52652211 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "skin 1: 4660.3" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 265.4" "Cancer enriched" "Detected in some" 5 "melanoma: 23.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Lineage enriched" "Detected in single" 14 "T-cells: 1.4" "Cell line enhanced" "Detected in single" "HEL: 2.0" "Group enriched" "Detected in some" 6 "amygdala: 1.7;hippocampal formation: 2.7" "Not detected" "Not detected" "HPA006299, CAB037321" Enhanced Approved "Golgi apparatus,Intermediate filaments,Cytosol" NA NA 9700000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 3: HMC-1 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments, Cytosol" "Golgi apparatus" "CAB037321: , HPA006299: AB_1079180" "unprognostic (1.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.56e-1)" "unprognostic (8.47e-3)" "unprognostic (1.69e-2)" "unprognostic (1.84e-1)" "unprognostic (3.59e-1)" "unprognostic (2.12e-1)" "unprognostic (4.76e-2)" "unprognostic (3.56e-7)" "unprognostic (6.43e-2)" "unprognostic (5.98e-3)" "unprognostic (6.69e-2)" "unprognostic (3.46e-1)" 3.0 0.5 0.0 0.1 0.0 1.0 81.9 0.0 0.0 0.8 0.0 0.9 1.6 0.4 0.3 1.1 0.1 0.0 1.7 0.0 0.0 0.5 1.2 1.0 0.5 0.0 0.0 0.5 1.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 1.6 0.0 47.8 4660.3 0.8 0.0 0.0 0.5 0.7 1.0 0.0 6.8 0.8 0.0 6.1 0.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.1 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 9.5 0.0 0.0 0.1 8.8 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 265.4 0.1 1.0 0.0 0.6 0.1 KRT23 "CK23, DKFZP434G032, HAIK1, K23, MGC26158" ENSG00000108244 "Keratin 23" Q9C075 17 40922700-40937646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "salivary gland: 147.7;skin 1: 172.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1328.6;Cytotrophoblasts: 679.8;Prostatic glandular cells: 2203.0;Syncytiotrophoblasts: 3890.8;Urothelial cells: 1590.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 61.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "HBEC3-KT: 9.6;Hep G2: 11.0;SuSa: 7.1;T-47d: 16.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012050, HPA016959, CAB017091" Approved Approved "Intermediate filaments,Cytosol" NA NA 590000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" Cytosol "CAB017091: , HPA012050: AB_1852226, HPA016959: AB_1852228" "unprognostic (1.62e-1)" "unprognostic (5.29e-2)" "unprognostic (4.35e-2)" "unprognostic (6.18e-3)" "unprognostic (1.45e-2)" "unprognostic (2.83e-1)" "unprognostic (5.22e-2)" "unprognostic (6.84e-3)" "unprognostic (2.74e-1)" "unprognostic (2.15e-2)" "unprognostic (8.96e-2)" "unprognostic (1.56e-1)" "unprognostic (8.22e-2)" "unprognostic (6.78e-2)" "unprognostic (1.40e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (8.26e-4)" 0.4 0.0 0.0 0.3 0.0 1.1 15.7 0.0 0.0 6.8 0.0 0.1 0.2 1.1 2.1 6.5 3.0 1.5 0.2 0.0 0.0 0.6 1.0 1.4 0.0 0.0 0.0 0.1 3.6 0.1 2.8 15.6 0.0 20.7 0.0 0.6 147.7 0.4 0.3 172.3 0.2 0.0 0.0 3.0 0.2 21.7 0.0 0.4 0.1 0.4 2.5 4.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.0 9.6 0.0 0.0 0.0 0.0 0.1 11.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 7.1 16.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.3 0.3 4.6 1328.6 242.1 0.6 0.0 78.0 27.9 0.4 12.8 390.5 3.7 0.0 679.8 1.1 0.1 1.9 462.9 66.2 49.8 7.8 15.1 7.1 0.0 0.5 0.8 109.3 15.0 0.0 66.4 0.0 0.0 0.0 0.0 63.8 0.0 0.3 0.7 57.0 0.0 0.7 10.6 0.6 3.0 5.4 0.0 5.4 15.8 0.0 0.5 0.3 17.7 1.1 0.7 0.0 2203.0 0.0 0.4 275.0 0.2 0.0 0.0 48.4 62.1 0.7 7.9 8.1 3890.8 7.6 0.1 0.9 1590.3 KRT24 "FLJ20261, MGC138169, MGC138173" ENSG00000167916 "Keratin 24" Q2M2I5 17 40697991-40703752 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "esophagus: 178.0;lymphoid tissue: 76.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.0;Fibroblasts: 4.6;Leydig cells: 3.1;Syncytiotrophoblasts: 4.0" "Group enriched" "Detected in some" 4 "cervical cancer: 9.6;head and neck cancer: 15.0;urothelial cancer: 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "SK-BR-3: 7.0" "Region enriched" "Detected in single" 10 "cerebellum: 1.0" "Low region specificity" "Detected in some" HPA022978 Uncertain Approved "Intermediate filaments,Cytosol" No NA 300000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments, Cytosol" "HPA022978: AB_1852230" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (3.75e-1)" "unprognostic (2.74e-1)" "unprognostic (2.95e-1)" "unprognostic (3.37e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.3 0.0 8.0 0.0 0.1 16.7 178.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 5.8 0.2 2.2 1.6 0.0 0.0 0.3 0.5 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 76.3 2.6 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.2 4.6 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 4.0 0.0 0.0 0.0 0.0 KRT25 KRT25A ENSG00000204897 "Keratin 25" Q7Z3Z0 17 40748021-40755331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "skin 1: 112.3" "Cell type enhanced" "Detected in some" "Early spermatids: 7.8;Late spermatids: 9.2;Spermatogonia: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPTEC TERT1: 1.3" "Region enriched" "Detected in some" 7 "cerebellum: 8.6" "Group enriched" "Detected in some" 5 "cerebral cortex: 7.3;hippocampal formation: 4.8" "HPA053977, HPA058943" Enhanced Approved Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA053977: AB_2682329, HPA058943: AB_2683859" "unprognostic (8.19e-2)" "unprognostic (5.89e-8)" "unprognostic (1.79e-1)" 2.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.3 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRT27 KRT25C ENSG00000171446 "Keratin 27" Q7Z3Y8 17 40776808-40782550 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "skin 1: 71.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.0;Endothelial cells: 1.5;Hepatic stellate cells: 2.2;Melanocytes: 8.8;Muller glia cells: 3.0;Spermatogonia: 2.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.9;thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "EFO-21: 1.4" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "hippocampal formation: 80.6" HPA055114 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA055114: AB_2682700" "unprognostic (1.13e-1)" "unprognostic (1.87e-1)" "unprognostic (2.18e-1)" "unprognostic (5.75e-4)" "unprognostic (5.11e-2)" "unprognostic (3.08e-2)" "unprognostic (8.41e-2)" "unprognostic (4.16e-1)" "unprognostic (1.53e-1)" "unprognostic (4.90e-1)" "unprognostic (1.56e-1)" "unprognostic (5.64e-3)" 1.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.4 0.1 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 8.8 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 2.3 0.0 0.4 0.3 0.0 0.0 0.0 0.0 KRT28 KRT25D ENSG00000173908 "Keratin 28" Q7Z3Y7 17 40792196-40799959 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "skin 1: 11.7" "Cell type enhanced" "Detected in single" "Spermatogonia: 1.3" "Cancer enhanced" "Detected in some" "cervical cancer: 0.6;endometrial cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 3.2" "Not detected" "Not detected" HPA066890 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 25: Spermatids - Spermatogenesis" "HPA066890: AB_2685742" 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRT3 "CK3, K3" ENSG00000186442 "Keratin 3" P12035 12 52789685-52796117 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 3.0;salivary gland: 10.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 0.7;head and neck cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 9.4;HMC-1: 5.6" "Region enhanced" "Detected in single" "cerebral cortex: 1.7" NA NA 280000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.03e-1)" "unprognostic (2.68e-2)" "unprognostic (2.42e-2)" "unprognostic (2.75e-1)" "unprognostic (9.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (1.54e-2)" "unprognostic (3.89e-2)" "unprognostic (2.54e-1)" "unprognostic (3.08e-2)" "unprognostic (1.73e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.3 0.8 0.0 0.0 0.0 0.0 KRT32 "Ha-2, KRTHA2" ENSG00000108759 "Keratin 32" Q14532 17 41459513-41467386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "esophagus: 5.9;skin 1: 19.5" "Group enriched" "Detected in some" 6 "Basal squamous epithelial cells: 21.6;Squamous epithelial cells: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTERT-RPE1: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 210000000 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.39e-2)" "unprognostic (3.29e-1)" "unprognostic (1.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.13e-1)" "unprognostic (3.46e-1)" "unprognostic (2.32e-2)" "unprognostic (2.67e-3)" "unprognostic (2.72e-9)" "unprognostic (1.31e-2)" "unprognostic (1.77e-1)" 0.6 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.1 0.0 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.8 21.6 0.0 0.3 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.4 0.0 0.4 KRT33B "Ha-3II, KRTHA3B" ENSG00000131738 "Keratin 33B" Q14525 17 41363498-41369813 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "skin 1: 82.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 2.9;Ionocytes: 2.0" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "BJ: 4.3;BJ hTERT+ SV40 Large T+ RasG12V: 1.1" HPA055194 Supported NA NA 350000000 "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA055194: AB_2682733" "unprognostic (3.34e-2)" "unprognostic (5.19e-2)" "unprognostic (3.04e-1)" "unprognostic (1.55e-2)" "unprognostic (6.28e-2)" 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 82.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 KRT34 "Ha-4, KRTHA4" ENSG00000131737 "Keratin 34" O76011 17 41377650-41382403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skin 1: 66.6" "Group enriched" "Detected in some" 8 "Early spermatids: 5.4;Late spermatids: 15.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "BJ: 201.8" "Not detected" "Not detected" "HPA055194, HPA072208" Enhanced Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA055194: AB_2682733, HPA072208: AB_2686494" "unprognostic (2.52e-1)" "unprognostic (2.14e-1)" "unprognostic (9.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.86e-3)" "unprognostic (5.12e-7)" "unprognostic (3.84e-2)" 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 1.1 1.8 0.0 1.6 0.0 0.0 0.0 0.1 1.9 0.0 201.8 8.8 23.5 46.4 0.0 0.1 0.0 0.0 25.1 0.1 0.0 0.0 0.0 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 8.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.1 26.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.0 0.3 0.0 0.0 KRT35 "Ha-5, KRTHA5" ENSG00000197079 "Keratin 35" Q92764 17 41476689-41481140 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 59.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025750, HPA078713" Enhanced Approved "Intermediate filaments" NA NA 220000000 "Cluster 61: Skin - Cornification" "Intermediate filaments" "HPA025750: , HPA078713: " 2.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 59.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "esophagus: 19735.6" "Cell type enriched" "Detected in some" 18 "Squamous epithelial cells: 5828.7" "Group enriched" "Detected in many" 5 "cervical cancer: 94.3;head and neck cancer: 151.8;stomach cancer: 73.1;urothelial cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "HaCaT: 734.9;SK-BR-3: 361.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 600000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB002154: AB_563803, HPA034881: AB_2674370" "unprognostic (4.04e-1)" "unprognostic (3.22e-3)" "unprognostic (5.16e-3)" "unprognostic (8.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.64e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.85e-3)" "unprognostic (2.84e-2)" "unprognostic (2.58e-11)" "unprognostic (1.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.26e-4)" 1.5 1.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 513.5 0.0 1.1 0.0 1.2 0.0 19735.6 9.5 3.1 7.2 0.0 0.0 0.9 2.6 17.3 0.0 0.0 0.0 1.8 2.8 0.0 8.9 0.0 0.0 4.3 0.0 0.0 2124.1 0.0 2.6 3.9 1.7 0.9 0.0 1.5 8.6 0.8 0.0 2.0 1.0 0.1 1418.0 4.4 1040.2 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.8 0.0 0.1 0.0 734.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.5 1.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.0 1.4 0.0 0.2 0.0 15.5 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 1.0 361.6 0.0 0.0 2.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 1.0 0.9 0.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 3.3 0.0 0.0 0.0 6.5 36.9 23.3 0.0 0.5 2.9 0.5 0.0 308.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 0.2 2.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 28.5 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.9 6.9 0.0 0.1 53.7 0.0 0.0 0.0 5.3 0.0 0.1 5828.7 0.0 0.0 2.0 0.0 0.0 54.4 KRT5 "EBS2, KRT5A" ENSG00000186081 "Keratin 5" P13647 12 52514575-52520530 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 5865.0;skin 1: 5885.4;vagina: 2150.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5870.1;Basal prostatic cells: 1037.6;Basal squamous epithelial cells: 1571.3;Squamous epithelial cells: 4370.9;Suprabasal keratinocytes: 2020.2" "Group enriched" "Detected in many" 4 "cervical cancer: 1863.2;head and neck cancer: 3340.4" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 326 "plasmacytoid DC: 32.6" "Lineage enriched" "Detected in single" 326 "dendritic cells: 32.6" "Group enriched" "Detected in some" 7 "HaCaT: 3368.0;HBEC3-KT: 5990.5;hTCEpi: 13326.8" "Region enriched" "Detected in many" 8 "spinal cord: 36.4" "CAB000027, CAB000129, HPA059479" Enhanced Approved "Intermediate filaments" NA NA 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000027: AB_2281083, CAB000129: , HPA059479: AB_2684034" "prognostic favorable (1.27e-4)" "unprognostic (9.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.29e-2)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" "unprognostic (7.20e-2)" "unprognostic (2.82e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-2)" "unprognostic (1.73e-1)" "unprognostic (6.01e-7)" "unprognostic (3.46e-2)" "unprognostic (5.56e-2)" "unprognostic (7.96e-2)" "unprognostic (2.81e-3)" 10.0 1.7 0.2 1.8 0.8 4.6 252.5 0.7 0.5 826.2 58.9 1.9 0.0 2.0 97.2 5865.0 12.5 2.0 3.8 1.7 0.0 1.3 3.5 6.4 3.0 0.1 0.0 2.2 4.7 0.1 8.2 2.0 0.1 125.8 0.0 0.0 880.3 100.0 9.9 5885.4 1.8 0.6 0.1 1.7 5.0 2.1 0.6 527.1 3.0 0.3 648.6 93.2 2150.9 0.4 50.6 0.0 0.0 0.0 2.3 0.2 0.8 0.0 0.0 0.0 0.0 1.0 0.3 2.4 0.5 0.2 0.0 3368.0 0.2 5990.5 0.2 0.0 0.0 0.2 0.1 0.0 0.6 1.4 2.8 0.3 13326.8 0.6 1049.7 0.0 0.8 0.0 1.8 4.0 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.2 1.0 1.2 0.8 0.9 0.0 0.1 1.2 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.9 0.5 0.2 10.1 1.0 0.9 4.0 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.1 0.2 0.8 0.7 0.5 1.7 0.0 0.1 0.0 0.1 0.1 0.6 0.4 1.7 0.0 1.1 0.0 0.4 5870.1 1037.6 627.1 1571.3 0.0 43.6 226.2 0.5 0.0 180.7 0.0 0.0 0.0 39.8 0.0 0.0 0.5 0.8 31.3 1.2 26.4 0.0 0.0 0.5 0.0 0.0 29.0 0.0 21.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 273.6 0.1 0.6 7.3 286.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 22.2 789.7 0.0 0.1 34.8 0.0 0.0 0.2 33.4 0.0 0.0 4370.9 2020.2 0.0 17.8 0.0 0.1 459.8 KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 2523.3;esophagus: 7338.5;vagina: 4945.4" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 674.0;Club cells: 200.5;Squamous epithelial cells: 876.0;Suprabasal keratinocytes: 151.4;Urothelial cells: 306.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3892.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "hTCEpi: 9761.7" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 4500000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (8.10e-3)" "unprognostic (2.11e-1)" "unprognostic (2.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (2.43e-1)" "unprognostic (3.73e-2)" "unprognostic (1.31e-3)" "unprognostic (1.29e-1)" "unprognostic (2.89e-9)" "unprognostic (8.80e-2)" "unprognostic (7.20e-2)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" 3.1 1.5 0.0 1.9 0.0 0.1 6.9 0.0 0.0 2523.3 0.0 1.2 0.0 1.3 0.0 7338.5 9.1 0.9 1.8 0.0 0.0 1.1 2.6 3.4 0.0 0.0 0.0 2.3 3.3 0.0 3.1 8.8 0.0 5.0 0.0 0.0 1025.5 0.0 1.9 480.0 1.3 0.4 0.0 1.4 4.9 1.0 0.0 33.6 1.5 0.0 628.6 19.7 4945.4 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 3.9 0.0 0.0 1143.8 0.0 2414.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.5 0.6 0.3 9761.7 0.2 306.7 0.0 0.3 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 14.0 0.3 0.1 0.5 0.0 0.3 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.2 0.2 0.4 0.9 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.5 79.0 674.0 12.0 0.0 0.6 1.7 0.0 0.0 200.5 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 2.6 0.2 0.8 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 5.5 0.0 0.0 0.7 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 100.4 0.0 0.0 24.5 0.0 0.0 0.0 11.8 0.0 0.0 876.0 151.4 0.0 1.7 0.0 0.1 306.8 KRT6B KRTL1 ENSG00000185479 "Keratin 6B" P04259 12 52446651-52452146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 228.2;esophagus: 934.5;skin 1: 285.1;vagina: 229.6" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 217.5" "Group enriched" "Detected in many" 5 "head and neck cancer: 1424.3;melanoma: 472.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 148.7" "CAB000130, HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "CAB000130: , HPA045697: AB_2679422, HPA061168: AB_2684440" "prognostic favorable (9.44e-4)" "unprognostic (3.27e-2)" "unprognostic (1.93e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-2)" "unprognostic (2.07e-3)" "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (5.77e-2)" "unprognostic (9.63e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (9.52e-4)" 0.9 0.2 0.0 2.0 0.0 0.1 16.2 0.0 0.0 228.2 0.0 0.5 0.0 0.1 0.0 934.5 0.2 0.2 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 0.7 0.0 0.3 0.0 0.0 0.2 0.0 0.0 168.6 0.0 0.3 285.1 0.2 0.0 0.0 0.1 0.7 0.2 0.0 2.1 0.1 0.0 74.3 0.2 229.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 27.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.7 1.1 0.0 0.1 13.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 20.6 1.8 40.4 0.0 0.0 28.7 16.8 0.1 0.0 16.3 0.0 0.0 0.0 0.9 0.3 0.0 46.2 1.8 0.0 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.0 0.0 1.7 1.3 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.6 0.0 0.0 2.8 0.0 0.0 0.0 1.4 0.0 0.2 217.5 32.7 0.0 0.3 0.0 0.6 5.9 KRT6C KRT6E ENSG00000170465 "Keratin 6C" P48668 12 52468516-52473805 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 211.7;esophagus: 799.4;vagina: 333.5" "Cell type enriched" "Detected in some" 60 "Squamous epithelial cells: 234.3" "Group enriched" "Detected in many" 5 "head and neck cancer: 564.7;melanoma: 242.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 94.1" "HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA045697: AB_2679422, HPA061168: AB_2684440" "unprognostic (3.18e-2)" "unprognostic (6.26e-3)" "unprognostic (6.63e-2)" "unprognostic (1.54e-3)" "unprognostic (6.97e-2)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (3.25e-2)" "unprognostic (2.24e-1)" "unprognostic (2.84e-1)" "unprognostic (4.50e-2)" 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 211.7 0.0 0.1 0.0 0.1 0.0 799.4 0.2 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 144.3 0.0 0.1 24.7 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.0 0.1 0.0 9.5 0.1 333.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 94.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.2 1.3 2.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 234.3 2.4 0.0 0.0 0.0 0.2 3.9 KRT7 "CK7, K2C7, K7, SCL" ENSG00000135480 "Keratin 7" P08729 12 52232520-52252186 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 905.8;thyroid gland: 593.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1756.7;Ductal cells: 2931.3;Exocrine glandular cells: 2143.5;Extravillous trophoblasts: 4196.1;Pancreatic endocrine cells: 6163.7;Prostatic glandular cells: 2386.6;Urothelial cells: 1900.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 560.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "intermediate monocyte: 1.1" "Lineage enriched" "Detected in single" 4 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "A549: 2418.2;BEWO: 2737.9;HBEC3-KT: 6225.3;hTERT-HME1: 2433.8;RT4: 7463.2;SiHa: 5833.6;SK-BR-3: 3363.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000028, HPA007272, HPA007315, CAB079970" Enhanced Approved "Intermediate filaments,Cytosol" NA NA 1300000000 "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Intermediate filaments" Cytosol "CAB000028: AB_2134589, CAB079970: , HPA007272: AB_1079181, HPA007315: " "unprognostic (2.71e-3)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.22e-2)" "unprognostic (8.59e-2)" "unprognostic (1.27e-1)" "unprognostic (5.44e-3)" "unprognostic (2.74e-1)" "prognostic unfavorable (9.42e-5)" "prognostic unfavorable (7.78e-5)" "unprognostic (4.54e-2)" "prognostic favorable (2.77e-9)" "unprognostic (2.82e-1)" "unprognostic (1.43e-2)" "unprognostic (3.28e-1)" "unprognostic (3.98e-3)" 27.1 0.7 0.0 1.4 0.0 0.3 272.9 0.0 0.2 48.4 0.0 1.6 0.4 12.9 15.2 91.7 75.9 82.4 5.6 0.0 0.0 147.5 14.2 325.2 1.7 0.2 0.0 2.4 57.4 5.6 12.0 265.1 0.2 58.1 0.7 0.3 905.8 213.2 1.7 78.3 1.3 0.4 0.1 0.8 17.8 0.8 0.1 3.3 593.0 2.0 6.7 389.8 20.1 0.4 4.9 2418.2 0.6 1.7 2.8 0.0 2737.9 509.6 0.6 261.3 23.6 7.6 1683.1 0.3 1.4 176.3 0.8 1871.6 0.2 6225.3 13.3 3.0 0.0 2.2 1179.8 8.0 57.4 1.5 1.5 1.3 380.7 1.3 2433.8 1.0 267.4 0.0 0.7 2.2 0.1 13.7 1.8 3.7 7.6 1.1 2.6 2.0 4.8 38.6 1520.5 7463.2 3.5 2.4 5833.6 3363.4 0.0 27.5 130.3 0.0 2028.2 1.9 3.7 2.4 1.1 1.8 0.4 2.0 2.0 1.6 1.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.4 8.1 653.9 109.4 0.0 2.5 3.6 1172.6 173.6 8.0 0.0 451.3 426.3 0.8 724.9 684.8 360.5 0.0 1756.7 8.9 2.2 135.0 2931.3 16.1 106.2 20.4 30.6 6.6 0.0 0.1 2143.5 4196.1 29.9 14.3 253.2 3.8 0.1 4.2 2.9 189.9 0.0 0.0 3.5 954.2 3.4 4.6 140.0 3.7 11.0 131.6 0.0 35.6 0.0 0.0 0.0 0.0 6163.7 0.3 0.4 1.4 2386.6 0.2 8.5 249.2 0.0 0.0 7.6 72.1 0.6 1.3 35.3 2.3 1442.5 9.2 0.0 4.4 1900.8 KRT71 "K6IRS1, KRT6IRS, KRT6IRS1" ENSG00000139648 "Keratin 71" Q3SY84 12 52543909-52553145 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skin 1: 100.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "CACO-2: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA049404 Enhanced NA NA 110000000 "Cluster 61: Skin - Cornification" "Cluster 39: CACO-2 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA049404: AB_2680748" "unprognostic (9.12e-2)" "unprognostic (2.38e-1)" "unprognostic (1.21e-1)" "unprognostic (1.04e-1)" "unprognostic (1.51e-1)" "unprognostic (2.18e-1)" "unprognostic (1.47e-1)" "unprognostic (3.14e-1)" "unprognostic (1.69e-2)" 2.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 KRT73 "K6IRS3, KRT6IRS3" ENSG00000186049 "Keratin 73" Q86Y46 12 52607570-52618559 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 17.0" "Cell type enriched" "Detected in some" 5 "NK-cells: 7.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "naive CD4 T-cell: 8.8;naive CD8 T-cell: 3.1" "Lineage enriched" "Detected in single" 13 "T-cells: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA044031 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 63: NK-cells & T-cells - Immune response" "HPA044031: AB_10963434" "unprognostic (2.23e-3)" "unprognostic (6.54e-2)" "unprognostic (3.05e-1)" "unprognostic (2.12e-3)" "unprognostic (2.11e-3)" "unprognostic (4.94e-1)" 0.3 0.0 0.0 0.7 0.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 17.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.0 8.8 3.1 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 7.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 KRT74 "K6IRS4, KRT5C, KRT6IRS4" ENSG00000170484 "Keratin 74" Q7RTS7 12 52565782-52573843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "epididymis: 5.6;skin 1: 16.3" "Cell type enriched" "Detected in some" 5 "Late spermatids: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040655, HPA048596" Enhanced Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 31: Spermatids - Spermatogenesis" "Intermediate filaments" "Nucleoli, Cytosol" "HPA040655: , HPA048596: AB_2680457" "unprognostic (6.75e-3)" "unprognostic (3.93e-1)" "unprognostic (1.60e-1)" "unprognostic (2.49e-2)" "unprognostic (9.46e-2)" "unprognostic (2.29e-1)" "unprognostic (8.54e-2)" "unprognostic (1.02e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRT76 "HUMCYT2A, KRT2B, KRT2P" ENSG00000185069 "Keratin 76" Q01546 12 52768155-52777345 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "lymphoid tissue: 2.5;salivary gland: 2.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "head and neck cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019656, HPA019696" Approved NA NA 310000000 "Cluster 16: Immune cells - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA019656: AB_1852241, HPA019696: AB_1852243" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRT77 KRT1B ENSG00000189182 "Keratin 77" Q7Z794 12 52689626-52703524 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 273.0" "Cell type enriched" "Detected in some" 8 "Suprabasal keratinocytes: 20.2" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 36 "HaCaT: 3.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045934 Enhanced Approved "Nuclear membrane,Plasma membrane" NA NA 1200000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Nuclear membrane, Plasma membrane" "HPA045934: AB_10960065" "unprognostic (3.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-1)" "unprognostic (2.61e-1)" "unprognostic (2.11e-1)" "unprognostic (2.06e-1)" 0.6 0.0 0.0 0.0 0.0 0.1 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 273.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 20.2 0.0 0.0 0.0 0.0 0.0 KRT79 "K6L, KRT6L" ENSG00000185640 "Keratin 79" Q5XKE5 12 52821408-52834311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 68.3" "Cell type enhanced" "Detected in some" "granulocytes: 4.5;Late spermatids: 1.1;Melanocytes: 3.6" "Group enriched" "Detected in some" 5 "breast cancer: 1.4;cervical cancer: 2.6;head and neck cancer: 2.7;melanoma: 1.6;urothelial cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HMC-1: 425.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA059347 Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA 1900000000 "Cluster 61: Skin - Cornification" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Nuclear membrane, Cytosol" "HPA059347: AB_2683986" "unprognostic (5.19e-3)" "unprognostic (1.56e-3)" "unprognostic (5.24e-2)" "unprognostic (2.38e-2)" "unprognostic (6.85e-2)" "unprognostic (6.36e-2)" "unprognostic (3.17e-1)" "unprognostic (7.92e-2)" "unprognostic (1.88e-2)" "unprognostic (1.60e-2)" "unprognostic (1.32e-1)" "unprognostic (2.72e-1)" "unprognostic (3.99e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 425.5 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 KRT8 "CARD2, CK8, CYK8, K2C8, K8, KO" ENSG00000170421 "Keratin 8" P05787 12 52897187-52949954 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1335.5;stomach 1: 800.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4302.8;Ductal cells: 6037.3;Exocrine glandular cells: 5457.6;Extravillous trophoblasts: 5323.4;Pancreatic endocrine cells: 5278.1;Paneth cells: 4937.3;Proximal enterocytes: 6802.6;Syncytiotrophoblasts: 5268.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 6130.6;BEWO: 3998.7;CACO-2: 7686.4;CAPAN-2: 4774.8;MCF7: 10521.8;SK-BR-3: 5126.4;T-47d: 4325.7" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 10 "spinal cord: 44.0" "CAB000131, CAB001696, HPA049866" Enhanced Supported "Intermediate filaments" NA NA 1700000000 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Intermediate filaments" "CAB000131: AB_2281144, CAB001696: , HPA049866: AB_2680923" "unprognostic (5.72e-2)" "unprognostic (2.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "unprognostic (2.76e-2)" "unprognostic (4.86e-3)" "unprognostic (3.10e-2)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (8.99e-2)" "unprognostic (2.08e-2)" "unprognostic (2.83e-2)" "unprognostic (3.18e-1)" "unprognostic (3.68e-1)" "unprognostic (1.19e-2)" 135.0 43.6 2.2 158.6 1.3 1.0 113.8 2.0 1.6 183.4 21.3 1079.2 1112.0 34.7 66.4 48.2 134.3 217.5 147.8 1.9 1.9 240.2 463.9 172.5 7.9 8.3 4.5 10.3 654.1 59.9 278.7 368.7 8.8 151.6 564.2 0.4 318.0 73.6 1.5 49.3 1335.5 50.6 0.4 16.3 800.1 7.6 4.9 47.6 237.5 0.3 13.8 209.0 36.7 1.7 2787.7 6130.6 0.2 7.8 0.7 3.2 3998.7 11.1 47.9 6.1 6.3 7686.4 4774.8 1.1 1130.2 14.7 6.9 947.1 17.6 752.6 5.9 4.6 130.8 4.3 1184.4 2234.2 212.8 1.2 2.4 9.5 12.6 14.8 50.8 419.9 17.0 1.0 484.7 1.7 0.1 10521.8 6.5 10.6 418.5 2740.6 132.8 3.8 2.2 15.2 1198.1 1354.5 129.9 5.0 1063.2 5126.4 7.8 1263.8 4325.7 10.5 18.8 5.7 443.4 9.3 10.0 1.6 7.0 7.6 3.3 1.7 13.4 1.3 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.1 0.7 0.2 0.1 0.1 0.4 0.5 0.1 1.7 0.1 0.2 2.2 1.3 2.0 1.6 1.9 1.9 8.3 4.5 8.8 0.4 4.9 1.7 7.7 400.6 176.5 0.3 26.9 6.0 1948.0 684.7 303.3 2.3 521.6 342.8 30.2 1069.5 734.8 491.1 0.0 2208.2 8.5 4302.8 297.4 6037.3 13.9 419.2 41.0 42.3 942.5 8.6 0.5 5457.6 5323.4 94.7 1740.1 557.1 76.3 88.0 24.3 310.9 252.2 1.7 0.5 2876.3 1625.5 9.9 7.2 69.9 8.1 22.2 131.6 0.0 55.0 3.4 1.0 1.0 0.3 5278.1 4937.3 1.9 6.6 994.7 6802.6 569.1 594.8 4.3 0.0 2.2 167.4 2.0 11.4 258.9 1.7 5268.8 33.4 13.4 2337.3 1542.5 KRT82 "Hb-2, KRTHB2" ENSG00000161850 "Keratin 82" Q9NSB4 12 52393931-52406335 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "skin 1: 12.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058715, HPA067230" Enhanced NA NA 29000000 "Cluster 61: Skin - Cornification" "HPA058715: AB_2683798, HPA067230: AB_2685807" "unprognostic (3.04e-1)" "unprognostic (3.59e-3)" 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 KRT86 "Hb6, KRTHB6, MNX" ENSG00000170442 "Keratin 86" O43790 12 52249300-52309163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "skin 1: 150.5" "Group enriched" "Detected in many" 4 "dendritic cells: 33.1;Early spermatids: 35.5;Late spermatids: 24.3;NK-cells: 11.3;T-cells: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 9 "basophil: 87.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 87.5" "Cell line enhanced" "Detected in many" "A-431: 24.9;A549: 25.7;MCF7: 51.6;RPMI-8226: 32.5;U-251 MG: 14.5" "HPA039798, HPA049778" Supported Approved Cytosol NA NA 160000000 "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA039798: AB_10674986, HPA049778: AB_2680877" "unprognostic (4.52e-2)" "unprognostic (6.83e-2)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (2.61e-2)" "unprognostic (6.49e-2)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (7.22e-2)" 1.2 0.5 0.5 0.2 0.7 2.6 0.5 0.0 0.5 0.2 0.0 0.5 0.4 0.4 0.5 0.1 0.7 0.4 0.1 0.8 0.2 0.2 0.1 0.7 0.0 0.3 0.4 0.1 2.1 0.1 0.1 0.4 0.4 0.3 0.0 0.1 3.8 0.3 0.3 150.5 0.3 0.1 0.2 0.1 0.2 4.0 0.5 0.2 4.1 0.0 0.1 0.8 0.2 1.2 24.9 25.7 0.0 0.0 0.0 0.0 0.3 0.9 0.7 0.3 0.1 0.3 1.3 0.0 1.1 0.0 0.5 1.5 0.0 4.5 0.1 10.9 0.0 0.0 5.4 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.5 12.7 0.0 0.0 0.0 1.8 0.0 51.6 0.0 3.0 0.1 0.2 6.1 0.0 0.0 32.5 0.4 3.2 2.9 0.0 4.5 2.0 2.0 0.0 1.4 0.0 0.8 0.0 1.3 0.1 14.5 0.0 0.0 0.0 0.0 5.3 0.0 87.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.5 0.5 0.7 0.0 0.5 0.8 0.2 0.3 0.4 0.4 0.2 0.5 1.2 0.1 0.0 0.6 0.0 0.3 0.6 2.9 2.0 0.0 0.4 2.8 3.4 0.4 2.8 3.1 0.0 0.0 0.1 33.1 0.2 0.0 2.1 35.5 3.6 0.8 0.2 0.0 0.0 0.5 5.1 1.6 0.3 1.1 4.9 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 2.0 0.0 1.1 24.3 0.3 0.3 1.8 0.0 0.0 0.2 11.3 0.0 0.5 2.9 0.0 0.0 2.1 2.7 0.0 0.6 1.9 0.3 0.0 1.0 0.4 0.8 0.4 0.0 0.1 1.2 14.2 0.0 0.0 3.5 KRTAP1-1 "HB2A, KAP1.1, KAP1.1A, KAP1.1B" ENSG00000188581 "Keratin associated protein 1-1" Q07627 17 41040541-41041450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 329 "skin 1: 81.3" "Group enriched" "Detected in some" 6 "Basal prostatic cells: 7.5;Ductal cells: 6.0;Prostatic glandular cells: 2.3;Urothelial cells: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.90e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 81.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 KRTAP1-3 KAP1.3 ENSG00000221880 "Keratin associated protein 1-3" Q8IUG1 17 41033884-41034874 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 322 "skin 1: 95.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRTAP1-4 KAP1.4 ENSG00000204887 "Keratin associated protein 1-4" P0C5Y4 17 41029697-41030104 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "skin 1: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 67: Proximal tubular cells - Tubular reabsorption" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP1-5 KAP1.5 ENSG00000221852 "Keratin associated protein 1-5" Q9BYS1 17 41026026-41027208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "skin 1: 79.0" "Group enriched" "Detected in some" 8 "Basal prostatic cells: 4.1;Syncytiotrophoblasts: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 3.9;BJ: 17.1;fHDF/TERT166: 10.6;HDLM-2: 6.5;U-138 MG: 4.6;U-87 MG: 3.4" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (1.76e-1)" "unprognostic (2.96e-2)" "unprognostic (2.24e-2)" "unprognostic (2.55e-1)" "unprognostic (1.90e-1)" "unprognostic (9.98e-2)" "unprognostic (1.80e-2)" "unprognostic (5.60e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 79.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.7 0.0 0.1 0.0 0.2 KRTAP19-1 KAP19.1 ENSG00000184351 "Keratin associated protein 19-1" Q8IUB9 21 30479706-30480367 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 116 "skin 1: 16.5" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 19 "melanoma: 17.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HEK 293: 20.8" NA NA "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "unprognostic (2.36e-2)" "unprognostic (8.67e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 KRTAP19-3 KAP19.3 ENSG00000244025 "Keratin associated protein 19-3" Q7Z4W3 21 30491462-30492013 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 89 "skeletal muscle: 6.7;skin 1: 15.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP19-5 KAP19.5 ENSG00000186977 "Keratin associated protein 19-5" Q3LI72 21 30501657-30502141 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "skin 1: 31.6" "Cell type enriched" "Detected in single" 22 "Syncytiotrophoblasts: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HEK 293: 4.3" NA NA 1600000 "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 KRTAP19-6 KAP19.6 ENSG00000186925 "Keratin associated protein 19-6" Q3LI70 21 30541535-30541864 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP19-7 KAP19.7 ENSG00000244362 "Keratin associated protein 19-7" Q3SYF9 21 30560875-30561314 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP2-1 KAP2.1A ENSG00000212725 "Keratin associated protein 2-1" Q9BYU5 17 41046541-41047316 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 399 "skin 1: 68.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059203 Supported NA NA "Cluster 61: Skin - Cornification" "HPA059203: AB_2683947" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 KRTAP2-2 KAP2.2 ENSG00000214518 "Keratin associated protein 2-2" Q9BYT5 17 41054498-41055230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 337 "skin 1: 54.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059203 Supported NA NA "Cluster 61: Skin - Cornification" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA059203: AB_2683947" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP2-3 KAP2.3 ENSG00000212724 "Keratin associated protein 2-3" P0C7H8 17 41059240-41060114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 104 "skin 1: 20.6" "Cell type enhanced" "Detected in some" "Ductal cells: 104.8;Endometrial ciliated cells: 22.0;Glandular and luminal cells: 35.5;Pancreatic endocrine cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 36.8;fHDF/TERT166: 22.2;HBF TERT88: 31.9;LHCN-M2: 41.0;U-2 OS: 15.9" HPA059203 Supported NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "HPA059203: AB_2683947" "unprognostic (2.22e-1)" "unprognostic (2.58e-2)" "unprognostic (3.79e-3)" "unprognostic (3.25e-3)" "unprognostic (2.78e-2)" "unprognostic (6.91e-2)" "unprognostic (1.38e-1)" "unprognostic (6.41e-4)" "unprognostic (7.83e-6)" "unprognostic (1.71e-1)" "unprognostic (9.36e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.1 0.0 36.8 1.2 9.0 7.6 0.4 0.3 0.0 0.0 22.2 2.2 0.1 0.0 0.6 31.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.3 0.5 0.6 0.0 0.0 0.0 0.0 41.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.2 0.0 5.4 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 15.9 1.0 1.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 1.5 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 104.8 0.0 22.0 1.6 0.4 0.0 0.0 0.0 0.6 0.4 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 KRTAP2-4 KAP2.4 ENSG00000213417 "Keratin associated protein 2-4" Q9BYR9 17 41065116-41065879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 437 "skin 1: 43.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059203 Supported NA NA "Cluster 61: Skin - Cornification" "HPA059203: AB_2683947" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP20-1 KAP20.1 ENSG00000244624 "Keratin associated protein 20-1" Q3LI63 21 30616425-30616699 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP20-2 KAP20.2 ENSG00000184032 "Keratin associated protein 20-2" Q3LI61 21 30635206-30635619 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "skin 1: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 23: Spermatids - Flagellum & Golgi organization" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP3-1 KAP3.1 ENSG00000212901 "Keratin associated protein 3-1" Q9BYR8 17 41008521-41019324 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 327 "skin 1: 231.0" "Cell type enriched" "Detected in some" 4 "Basal prostatic cells: 581.4" "Cancer enhanced" "Detected in some" "stomach cancer: 2.8;urothelial cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.0;BJ: 4.9;CACO-2: 12.7;HaCaT: 2.4;T-47d: 2.0" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (4.24e-1)" "unprognostic (3.00e-2)" "unprognostic (7.37e-2)" 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 231.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 581.4 0.0 4.0 0.0 0.9 0.0 0.0 0.0 3.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.1 0.3 1.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.6 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 1.3 0.0 1.4 11.2 0.0 0.0 71.8 KRTAP3-2 KAP3.2 ENSG00000212900 "Keratin associated protein 3-2" Q9BYR7 17 40999193-40999906 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 107.6" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.2;Squamous epithelial cells: 4.8;Suprabasal keratinocytes: 1.1;Urothelial cells: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042992 Approved NA NA "Cluster 61: Skin - Cornification" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA042992: AB_2678258" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 107.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 1.1 0.0 0.0 0.0 0.0 2.6 KRTAP3-3 KAP3.3 ENSG00000212899 "Keratin associated protein 3-3" Q9BYR6 17 40993430-40994164 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 209 "skin 1: 129.3" "Cell type enriched" "Detected in single" 4 "Enteroendocrine cells: 1.8" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042992 Supported NA NA "Cluster 61: Skin - Cornification" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA042992: AB_2678258" 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 129.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-1 "KAP4.1, KAP4.10, KRTAP4-10" ENSG00000198443 "Keratin associated protein 4-1" Q9BYQ7 17 41184102-41185342 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 68 "skin 1: 26.6" "Cell type enhanced" "Detected in single" "Enteroendocrine cells: 1.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.1;A549: 1.7;CAPAN-2: 1.2;HDLM-2: 4.9;SCLC-21H: 1.2;SK-BR-3: 1.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.21e-1)" "unprognostic (3.57e-1)" "unprognostic (1.64e-2)" "unprognostic (2.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.49e-2)" "unprognostic (2.42e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 26.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 KRTAP4-11 "KAP4.11, KAP4.14, KRTAP4-14" ENSG00000212721 "Keratin associated protein 4-11" Q9BYQ6 17 41117181-41118373 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 96 "skin 1: 9.6" "Cell type enhanced" "Detected in single" "B-cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-12 KAP4.12 ENSG00000213416 "Keratin associated protein 4-12" Q9BQ66 17 41123091-41124182 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 269 "skin 1: 26.8" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.3;Urothelial cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enhanced" "Detected in single" "B-cells: 1.0" "Not detected" "Not detected" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 61: Skin - Cornification" "Cluster 22: Epithelial cell types - Mixed function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 KRTAP4-16 "KAP4A, KRTAP4-16P, KRTAP4P1" ENSG00000241241 "Keratin associated protein 4-16" 17 41101502-41102209 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.7 0.3 0.4 0.6 0.3 0.6 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-2 KAP4.2 ENSG00000244537 "Keratin associated protein 4-2" Q9BYR5 17 41177446-41178221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 228 "skin 1: 22.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-3 KAP4.3 ENSG00000196156 "Keratin associated protein 4-3" Q9BYR4 17 41167231-41168221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 179 "skin 1: 17.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "HDLM-2: 1.1" "Not detected" "Not detected" NA NA 1400000 "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 KRTAP4-4 "KAP4.13, KAP4.4, KRTAP4-13" ENSG00000171396 "Keratin associated protein 4-4" Q9BYR3 17 41159649-41160748 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 188 "skin 1: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 1500000 "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-5 KAP4.5 ENSG00000198271 "Keratin associated protein 4-5" Q9BYR2 17 41148924-41149825 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 124 "skin 1: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRTAP4-6 "KAP4.15, KAP4.6, KRTAP4-15" ENSG00000198090 "Keratin associated protein 4-6" Q9BYQ5 17 41139433-41140487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 341 "skin 1: 34.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 15000000 "Cluster 61: Skin - Cornification" "Cluster 44: Endometrium - Transcription" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-7 KAP4.7 ENSG00000240871 "Keratin associated protein 4-7" Q9BYR0 17 41084150-41085141 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 580 "skin 1: 58.0" "Cell type enhanced" "Detected in single" "Endometrial ciliated cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: Endometrium - Transcription" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-8 KAP4.8 ENSG00000204880 "Keratin associated protein 4-8" Q9BYQ9 17 41096981-41098142 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 247 "skin 1: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 6900000 "Cluster 61: Skin - Cornification" "Cluster 44: Endometrium - Transcription" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP4-9 KAP4.9 ENSG00000212722 "Keratin associated protein 4-9" Q9BYQ8 17 41105332-41106488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 488 "skin 1: 48.8" "Cell type enhanced" "Detected in single" "Glandular and luminal cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: Endometrium - Transcription" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRTAP5-6 KRTAP5.6 ENSG00000205864 "Keratin associated protein 5-6" Q6L8G9 11 1697195-1697755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.0;skin 1: 1.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "liver cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 85: Liver - Metabolism" "prognostic favorable (6.04e-5)" "unprognostic (3.70e-1)" "unprognostic (2.93e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP6-1 "C21orf103, KAP6.1" ENSG00000184724 "Keratin associated protein 6-1" Q3LI64 21 30613431-30613930 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "skin 1: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP7-1 KAP7.1 ENSG00000274749 "Keratin associated protein 7-1" Q8IUC3 21 30829039-30829759 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 104 "skin 1: 25.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "urothelial cancer: 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 61: Skin - Cornification" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP8-1 KAP8.1 ENSG00000183640 "Keratin associated protein 8-1" Q8IUC2 21 30812697-30813274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 86 "skin 1: 61.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "urothelial cancer: 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 34: Spermatids - Unknown function" 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 61.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-1 "KAP9.1, KRTAP9L3" ENSG00000240542 "Keratin associated protein 9-1" A8MXZ3 17 41189887-41190639 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 46 "HDLM-2: 4.5" NA NA "Cluster 44: HDLM-2 - Immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-2 KAP9.2 ENSG00000239886 "Keratin associated protein 9-2" Q9BYQ4 17 41226648-41227652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 225 "skin 1: 32.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-3 KAP9.3 ENSG00000204873 "Keratin associated protein 9-3" Q9BYQ3 17 41232449-41233454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 494 "skin 1: 49.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-4 KAP9.4 ENSG00000241595 "Keratin associated protein 9-4" Q9BYQ2 17 41249687-41250653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 400 "skin 1: 39.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 KRTAP9-6 "KAP9.6, KRTAP9L2" ENSG00000212659 "Keratin associated protein 9-6" A8MVA2 17 41265339-41266641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "skin 1: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 KRTAP9-7 "KAP9.7, KRTAP9L1" ENSG00000180386 "Keratin associated protein 9-7" A8MTY7 17 41275659-41276697 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 81 "skin 1: 8.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 2900000 "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-8 KAP9.8 ENSG00000187272 "Keratin associated protein 9-8" Q9BYQ0 17 41237999-41239004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 383 "skin 1: 38.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 31 "HDLM-2: 3.1" NA NA "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRTAP9-9 "KAP9.5, KAP9.9, KRTAP9-5" ENSG00000198083 "Keratin associated protein 9-9" Q9BYP9 17 41255384-41256364 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 248 "skin 1: 24.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KTI12 "MGC20419, SBBI81, TOT4" ENSG00000198841 "KTI12 chromatin associated homolog" Q96EK9 1 52032103-52033810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031203, HPA031204, HPA031205" Approved Approved "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Cytoplasmic bodies" "HPA031203: AB_2732464, HPA031204: AB_10600110, HPA031205: AB_10611380" "unprognostic (6.14e-2)" "unprognostic (9.45e-2)" "unprognostic (1.19e-3)" "unprognostic (3.36e-3)" "unprognostic (4.18e-1)" "unprognostic (1.83e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.74e-1)" "unprognostic (2.94e-1)" "unprognostic (3.72e-2)" "unprognostic (4.06e-2)" "unprognostic (8.08e-3)" "unprognostic (6.59e-2)" "unprognostic (3.36e-3)" "unprognostic (2.39e-1)" "unprognostic (3.59e-2)" "unprognostic (1.64e-2)" 7.5 10.2 4.2 6.9 4.0 16.7 5.9 4.5 4.4 4.5 4.9 6.5 4.9 7.3 4.7 5.8 6.9 3.8 5.1 4.0 5.0 4.9 6.8 4.2 8.7 4.5 4.1 9.2 6.8 3.9 6.4 4.2 4.1 4.0 4.0 2.5 4.0 4.7 4.6 5.5 7.6 4.7 4.1 8.5 7.1 7.2 4.9 6.6 4.0 3.5 7.6 5.5 3.8 4.4 14.0 13.4 5.3 12.5 17.8 14.8 16.6 13.9 17.0 20.1 17.1 15.2 6.7 16.0 15.3 14.5 29.8 15.6 18.7 16.4 13.9 16.5 20.9 16.6 14.6 14.9 12.3 23.8 15.7 13.9 12.5 16.0 8.6 8.7 13.8 14.0 25.2 7.7 17.1 11.1 17.5 26.7 10.3 12.2 14.9 16.3 14.6 21.5 19.4 10.0 9.3 13.5 13.4 23.3 25.8 12.0 4.5 37.2 10.4 16.2 10.1 19.4 26.3 28.6 25.8 25.4 17.9 25.2 12.1 17.0 21.6 16.4 22.1 24.5 24.9 29.8 24.7 27.0 29.4 22.7 29.0 20.7 4.5 24.2 19.3 44.6 26.9 18.8 4.2 4.0 4.5 4.4 4.0 5.0 4.5 4.1 4.1 4.1 4.9 4.4 10.8 3.2 5.1 0.0 14.3 7.1 13.2 14.1 5.7 6.1 5.3 6.1 3.1 8.6 6.3 3.7 0.0 12.1 17.5 1.8 5.9 11.3 2.3 4.4 10.6 8.4 2.4 8.6 0.0 10.9 17.0 8.6 3.1 3.9 6.3 26.3 9.3 5.9 10.0 10.1 0.0 3.9 6.1 6.6 6.4 1.2 11.5 6.0 5.4 0.0 13.6 9.7 10.3 0.0 0.0 10.5 3.4 10.1 9.5 7.8 3.1 11.6 4.7 4.9 19.7 8.1 10.7 20.3 9.3 6.7 7.4 18.3 10.6 28.1 4.7 11.5 L2HGDH "C14orf160, FLJ12618" ENSG00000087299 "L-2-hydroxyglutarate dehydrogenase" Q9H9P8 14 50237563-50312229 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Excitatory neurons: 60.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065409, HPA069708" Approved Enhanced Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA065409: AB_2685485, HPA069708: AB_2686179" "unprognostic (1.74e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (1.23e-3)" "unprognostic (1.04e-2)" "unprognostic (4.33e-2)" "unprognostic (8.84e-2)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (9.91e-2)" "unprognostic (2.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (9.75e-10)" "unprognostic (1.24e-2)" "unprognostic (5.88e-2)" "unprognostic (1.45e-1)" "unprognostic (1.02e-2)" 4.6 2.5 2.9 2.2 2.9 2.7 3.7 6.1 5.5 2.3 1.3 4.3 4.7 2.4 3.0 5.1 3.1 2.0 5.2 2.7 2.5 19.6 12.6 1.8 2.6 1.2 2.4 2.5 3.9 6.1 2.3 1.7 1.1 3.3 5.0 11.4 2.8 3.2 15.5 5.1 3.6 2.5 1.2 1.3 4.3 3.9 2.4 3.0 4.8 14.7 3.4 2.4 2.3 4.1 24.3 16.6 6.8 6.6 3.3 2.2 19.1 7.9 4.4 12.2 14.3 26.8 10.8 19.0 9.0 3.2 9.7 17.4 20.6 8.2 13.5 15.2 11.9 41.1 10.9 3.7 3.1 14.7 13.7 2.0 5.2 8.1 7.0 3.1 5.3 19.3 14.7 11.6 3.2 29.0 16.7 6.7 9.9 20.6 17.6 15.6 22.0 14.8 11.4 28.0 13.8 9.9 23.3 17.5 10.4 9.0 22.9 4.0 5.0 7.7 21.5 9.0 10.6 10.5 25.6 26.3 4.3 7.3 8.8 8.6 0.4 0.9 0.9 0.1 2.2 0.8 1.1 1.0 0.6 0.6 1.3 1.7 0.5 1.7 0.1 1.0 1.6 0.5 2.9 2.9 6.1 5.5 2.7 2.5 1.2 2.4 1.1 1.2 2.4 4.1 1.9 41.7 19.2 16.6 5.1 3.7 2.7 2.1 8.6 15.5 3.9 2.2 14.7 2.8 20.4 12.9 56.3 6.4 6.1 4.8 15.6 3.8 35.1 5.2 2.8 4.6 7.8 7.4 60.5 4.2 6.6 5.3 7.7 5.6 18.9 6.0 2.9 14.2 2.1 11.8 61.4 4.3 0.0 2.7 0.6 8.8 2.5 3.3 1.8 13.1 2.4 6.1 7.2 20.6 18.9 2.5 3.6 4.5 3.3 2.7 6.0 21.7 18.4 40.3 0.0 5.8 3.9 14.3 12.6 10.5 6.3 4.9 5.0 4.6 7.6 2.1 L3MBTL4 "FLJ35936, HsT1031" ENSG00000154655 "L3MBTL histone methyl-lysine binding protein 4" Q8NA19 18 5954706-6415237 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 160.4;Late spermatids: 85.8;Microglial cells: 78.7;Oligodendrocyte precursor cells: 191.5;Oligodendrocytes: 252.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 3.4;Karpas-707: 4.8;RPMI-8226: 11.6;SCLC-21H: 5.3;SH-SY5Y: 5.8;U-2 OS: 3.4" "Low region specificity" "Detected in some" "HPA064194, HPA069042" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "HPA064194: AB_2685208, HPA069042: AB_2686071" "unprognostic (1.33e-3)" "unprognostic (8.98e-2)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (3.56e-2)" "unprognostic (1.40e-1)" "unprognostic (1.70e-2)" "unprognostic (1.73e-1)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (1.92e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-2)" "unprognostic (5.08e-2)" "unprognostic (1.00e-1)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" 3.0 4.3 7.1 1.8 11.5 1.6 4.9 0.2 8.4 4.3 0.6 2.1 3.0 3.2 3.6 3.6 4.2 2.5 4.9 3.8 6.8 7.1 8.8 3.9 2.0 3.3 8.2 8.5 6.5 8.5 3.2 0.7 4.7 2.0 2.0 1.7 3.4 2.9 1.0 7.3 3.5 1.3 1.6 2.9 3.2 12.7 6.6 2.9 5.8 1.3 1.6 1.4 4.1 14.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 2.4 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.2 0.0 1.4 3.1 0.0 11.6 0.0 2.0 5.3 5.8 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 3.4 0.1 1.4 0.1 0.0 0.0 1.3 0.0 1.7 0.3 1.1 0.0 0.7 0.3 0.0 0.5 0.1 0.1 0.7 2.5 0.1 0.2 0.1 3.6 0.8 0.1 0.0 0.5 7.1 11.5 0.2 8.4 3.8 6.8 3.3 8.2 4.7 1.6 6.6 14.0 6.5 3.2 12.2 56.2 4.8 7.8 7.0 0.8 10.2 2.2 4.5 4.8 6.4 11.5 4.1 5.5 16.7 0.1 2.7 0.3 3.9 7.4 62.5 8.1 1.2 3.6 11.4 0.8 33.9 5.2 0.0 3.4 1.5 16.9 1.3 15.4 2.5 10.0 3.2 0.0 160.4 1.5 0.0 3.2 5.3 85.8 10.2 2.9 1.8 78.7 27.2 1.8 25.7 191.5 252.9 3.5 1.9 12.8 1.5 10.3 3.5 8.1 1.2 0.6 6.6 6.9 7.2 9.3 2.4 6.5 8.2 0.1 2.1 0.5 2.5 4.6 LACRT LACRITIN ENSG00000135413 Lacritin Q9GZZ8 12 54630811-54634895 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "salivary gland: 13.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 304 "breast cancer: 15.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA 230000 "Cluster 24: Salivary gland - Salivary secretion" 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 362.1;skin 1: 215.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 174.7;Ductal cells: 178.0;monocytes: 248.6;Pancreatic endocrine cells: 227.0;Proximal enterocytes: 214.7;Squamous epithelial cells: 265.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 159.9;CAPAN-2: 158.5;HaCaT: 220.4;HBEC3-KT: 190.3;hTCEpi: 181.5;MCF7: 218.3;OE19: 246.5;RT4: 164.7;SK-BR-3: 250.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Actin filaments" "HPA007256: AB_1852681, HPA028732: AB_10602916" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.82e-1)" "unprognostic (7.55e-3)" "unprognostic (4.66e-2)" "unprognostic (7.41e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (9.11e-2)" "unprognostic (2.31e-2)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" 0.5 0.1 0.0 15.9 0.1 0.1 15.8 0.0 0.2 65.4 0.0 67.6 75.6 5.0 11.0 362.1 14.7 50.2 8.4 0.2 0.6 38.6 21.6 10.6 2.9 0.0 0.0 0.4 50.7 2.4 0.7 4.1 0.0 15.7 51.0 0.0 51.9 22.6 5.1 215.4 74.5 2.9 0.0 1.4 66.9 0.3 0.0 6.2 3.5 0.2 47.7 71.4 135.2 0.0 159.9 1.3 0.0 0.3 0.0 0.0 57.0 0.0 0.0 0.1 0.1 127.3 158.5 0.0 8.9 0.0 0.0 220.4 0.0 190.3 0.1 0.2 0.0 0.0 0.1 79.3 0.0 0.1 0.2 0.1 181.5 0.1 36.8 0.0 0.1 0.0 0.1 0.7 0.1 218.3 0.2 0.4 3.7 246.5 2.6 0.2 7.4 2.3 126.0 164.7 9.1 0.2 0.1 250.6 3.1 5.4 37.6 0.4 0.0 0.1 0.5 0.5 0.6 0.1 0.4 0.2 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 35.4 0.0 0.9 88.5 112.1 47.2 46.7 0.0 15.4 14.1 2.1 110.1 31.3 31.3 0.0 3.8 0.5 174.7 45.0 178.0 1.1 26.2 2.6 1.6 18.1 0.0 0.0 121.9 5.9 2.6 85.1 34.5 0.0 0.0 0.4 9.0 0.5 0.0 0.0 53.8 18.3 0.6 16.0 3.6 0.0 2.6 10.6 0.0 248.6 0.0 0.0 0.0 0.0 227.0 109.6 0.4 2.9 77.1 214.7 71.8 4.8 0.0 0.0 0.0 3.2 0.0 0.3 265.6 152.7 10.4 1.5 0.0 136.2 150.2 LAMA1 LAMA ENSG00000101680 "Laminin subunit alpha 1" P25391 18 6941742-7117797 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.9" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Distal enterocytes: 173.6;Granulosa cells: 77.3;Intestinal goblet cells: 44.2;Paneth cells: 35.8;Proximal enterocytes: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 56.0;ASC diff: 41.0;BEWO: 199.6;hTEC/SVTERT24-B: 41.7;SK-MEL-30: 38.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB010179 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010179: AB_2133741" "unprognostic (2.75e-1)" "unprognostic (3.66e-4)" "unprognostic (2.08e-1)" "unprognostic (3.56e-1)" "unprognostic (4.97e-3)" "unprognostic (3.66e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (2.23e-2)" "unprognostic (3.43e-2)" "unprognostic (3.02e-1)" "unprognostic (6.80e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-2)" "unprognostic (4.85e-1)" "unprognostic (3.47e-2)" "unprognostic (7.34e-3)" 0.7 0.0 2.0 0.2 1.5 0.0 1.6 1.9 1.1 0.8 0.5 0.1 0.0 0.9 1.4 0.1 0.2 0.0 0.2 2.0 2.0 2.9 0.1 0.3 0.0 2.0 2.8 1.4 1.1 0.0 1.0 0.1 2.1 0.2 0.0 0.4 1.3 0.6 0.0 0.2 0.0 0.3 2.2 0.1 0.0 5.9 3.0 0.1 2.5 0.0 0.0 0.3 0.2 2.9 0.0 0.0 56.0 0.0 41.0 36.5 199.6 2.0 9.8 9.9 21.5 24.4 0.0 0.0 0.5 3.4 8.0 0.1 0.0 7.3 4.1 0.0 3.2 0.0 11.8 0.0 4.8 0.0 0.0 31.1 1.1 41.7 23.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 2.8 0.0 0.0 38.4 11.6 0.0 0.0 0.0 7.5 20.5 4.2 0.1 0.0 0.0 0.0 3.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 1.9 1.1 2.0 2.0 2.0 2.8 2.1 2.2 3.0 2.9 2.6 6.4 0.0 90.8 0.0 0.0 0.8 0.8 0.6 0.5 2.3 7.2 1.9 4.3 0.0 0.0 0.0 4.1 0.0 173.6 0.0 0.0 1.6 4.1 0.6 0.2 1.2 0.0 1.4 0.5 3.1 4.2 0.0 4.3 0.0 77.3 0.0 0.1 0.9 0.0 1.7 44.2 0.0 0.0 0.0 3.7 0.0 0.2 0.0 15.0 0.0 3.4 0.0 4.0 1.8 0.0 35.8 0.0 0.0 1.0 47.5 1.4 0.1 0.3 0.0 0.6 3.4 0.4 2.5 0.3 0.0 4.8 0.2 4.6 16.5 0.3 LARS2 "KIAA0028, LEURS, MGC26121, mtLeuRS" ENSG00000011376 "Leucyl-tRNA synthetase 2, mitochondrial" Q15031 3 45388561-45554726 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Excitatory neurons: 35.4;Inhibitory neurons: 37.8;Oligodendrocyte precursor cells: 22.6;Oligodendrocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035951, HPA045450, HPA066085" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Nucleoplasm "HPA035951: AB_10672997, HPA045450: AB_2679328, HPA066085: AB_2685612" "unprognostic (3.89e-1)" "unprognostic (3.89e-1)" "prognostic favorable (1.71e-4)" "unprognostic (3.02e-2)" "unprognostic (3.77e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-3)" "unprognostic (9.19e-2)" "unprognostic (6.13e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-1)" "unprognostic (4.37e-2)" "prognostic favorable (1.32e-11)" "unprognostic (2.81e-1)" "unprognostic (5.74e-2)" "unprognostic (9.90e-2)" "unprognostic (9.07e-2)" 3.3 4.7 9.5 3.4 10.3 2.4 3.9 10.1 11.7 3.7 9.2 6.9 3.9 4.6 4.3 4.2 4.5 3.0 5.5 9.3 10.5 7.5 8.1 2.9 4.3 9.5 10.2 3.8 2.4 12.3 3.7 4.2 9.5 4.3 6.9 4.2 3.6 4.2 6.2 3.6 2.9 4.4 9.2 3.2 3.6 2.2 11.5 6.9 4.5 6.4 4.8 5.0 3.7 8.5 6.3 11.2 10.7 9.3 11.8 13.0 11.1 11.6 15.7 24.7 16.2 20.3 8.8 13.8 8.9 18.0 18.2 5.8 49.0 30.4 16.0 9.5 12.7 12.9 13.6 18.4 12.1 20.9 4.4 19.0 16.8 26.0 12.5 13.1 14.9 19.5 25.1 5.5 19.0 9.7 21.1 11.6 28.4 15.0 21.9 8.9 9.8 16.9 23.6 18.8 7.6 9.7 17.3 7.9 11.8 13.5 14.6 14.7 9.1 12.1 8.3 8.5 12.3 5.3 12.3 15.4 14.0 16.9 9.5 0.0 0.6 0.6 1.2 0.9 1.5 1.0 0.7 1.1 1.2 0.5 0.8 1.0 0.3 1.9 0.8 1.0 0.6 0.7 9.5 10.3 10.1 11.7 9.3 10.5 9.5 10.2 9.5 9.2 11.5 8.5 3.9 0.0 2.0 28.7 4.8 1.1 1.5 1.8 3.4 5.5 3.2 2.8 9.0 1.5 1.8 5.5 4.2 5.0 3.5 4.4 5.9 2.9 0.6 7.6 5.7 4.2 4.8 5.2 35.4 2.7 5.2 3.2 6.6 4.9 1.3 9.8 2.2 7.7 5.4 1.7 37.8 4.5 0.0 2.9 1.3 1.2 1.2 2.6 1.8 19.7 2.3 4.0 2.1 22.6 25.2 3.2 7.0 2.2 5.0 1.9 2.6 2.4 2.9 4.7 0.0 3.1 2.9 0.7 2.4 4.8 1.3 2.9 3.2 8.3 6.8 1.7 LCE1A LEP1 ENSG00000186844 "Late cornified envelope 1A" Q5T7P2 1 152827473-152828097 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skin 1: 269.6" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 40.3" "Cancer enriched" "Detected in some" 6 "melanoma: 14.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 23.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 269.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 40.3 0.0 0.1 0.0 0.0 0.0 LCE1B "LEP2, SPRL2A" ENSG00000196734 "Late cornified envelope 1B" Q5T7P3 1 152811971-152813108 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "skin 1: 167.5" "Cell type enriched" "Detected in some" 18 "Suprabasal keratinocytes: 18.9" "Cancer enriched" "Detected in some" 10 "melanoma: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 2.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.79e-1)" "unprognostic (1.24e-2)" "unprognostic (6.43e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 167.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 LCE1C LEP3 ENSG00000197084 "Late cornified envelope 1C" Q5T751 1 152804835-152806628 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 596.1" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 83.0" "Cancer enriched" "Detected in some" 6 "melanoma: 17.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ hTERT+: 1.0;HBEC3-KT: 2.2;hTEC/SVTERT24-B: 1.1;hTERT-HME1: 2.8" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.35e-2)" "unprognostic (5.95e-2)" "unprognostic (3.46e-2)" "unprognostic (3.35e-2)" 0.3 0.1 0.0 0.0 0.0 0.3 34.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 4.1 596.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 3.5 2.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.2 83.0 0.0 0.2 0.0 0.0 0.0 LCE1D LEP4 ENSG00000172155 "Late cornified envelope 1D" Q5T752 1 152796721-152798181 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 93 "skin 1: 80.8" "Cell type enriched" "Detected in single" 42 "Suprabasal keratinocytes: 12.6" "Cancer enriched" "Detected in single" 8 "melanoma: 4.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (7.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 80.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 LCE1E LEP5 ENSG00000186226 "Late cornified envelope 1E" Q5T753 1 152786214-152788426 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "skin 1: 61.4" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 18.3" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HaCaT: 10.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (9.92e-2)" "unprognostic (9.50e-2)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 61.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 10.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 18.3 0.0 0.1 0.0 0.0 0.0 LCE1F LEP6 ENSG00000240386 "Late cornified envelope 1F" Q5T754 1 152776372-152776728 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skin 1: 209.8" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 18.3" "Group enriched" "Detected in some" 13 "head and neck cancer: 5.5;melanoma: 14.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ hTERT+: 6.5;hTERT-HME1: 3.0" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.21e-1)" "unprognostic (8.43e-2)" 0.0 0.0 0.0 0.0 0.0 0.2 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 209.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 LCE2A LEP9 ENSG00000187173 "Late cornified envelope 2A" Q5TA79 1 152698345-152699442 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 118.2" "Cell type enriched" "Detected in single" 4 "Melanocytes: 1.8" "Cancer enriched" "Detected in some" 5 "melanoma: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 5.6;SK-MEL-30: 2.0;U-2197: 1.4" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (3.45e-2)" "unprognostic (6.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 118.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.9 0.0 1.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 LCE2B "LEP10, SPRL1B, XP5" ENSG00000159455 "Late cornified envelope 2B" O14633 1 152686123-152687397 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 719.8" "Cell type enriched" "Detected in some" 17 "Suprabasal keratinocytes: 31.5" "Cancer enriched" "Detected in some" 5 "melanoma: 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.04e-2)" "unprognostic (1.36e-1)" 0.5 0.1 0.0 0.0 0.0 0.0 42.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 6.1 719.8 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.0 0.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 31.5 0.0 0.1 0.0 0.0 0.0 LCE2C LEP11 ENSG00000187180 "Late cornified envelope 2C" Q5TA81 1 152675295-152676574 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 321.2" "Cell type enriched" "Detected in single" 35 "Suprabasal keratinocytes: 14.2" "Cancer enriched" "Detected in some" 5 "melanoma: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (1.47e-2)" "unprognostic (7.00e-2)" 0.2 0.0 0.0 0.0 0.0 0.1 22.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 321.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 LCE2D "LEP12, SPRL1A" ENSG00000187223 "Late cornified envelope 2D" Q5TA82 1 152663380-152664659 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "skin 1: 152.1" "Group enriched" "Detected in some" 8 "Melanocytes: 1.8;Suprabasal keratinocytes: 4.7" "Group enriched" "Detected in some" 42 "head and neck cancer: 1.2;melanoma: 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (3.94e-2)" "unprognostic (5.63e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 152.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 LCE4A "LEP8, SPRL4A" ENSG00000187170 "Late cornified envelope 4A" Q5TA78 1 152708160-152709491 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "skin 1: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "unprognostic (1.61e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LCE5A "LEP18, SPRL5A" ENSG00000186207 "Late cornified envelope 5A" Q5TCM9 1 152510803-152512177 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 91.5" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 7.4" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.51e-1)" "unprognostic (7.27e-3)" "unprognostic (9.27e-2)" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 11.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 91.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 LCE6A C1orf44 ENSG00000235942 "Late cornified envelope 6A" A0A183 1 152842856-152843983 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 246.6" "Cell type enriched" "Detected in single" 8 "Suprabasal keratinocytes: 2.6" "Cancer enriched" "Detected in some" 5 "melanoma: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046376 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA046376: AB_10965998" "unprognostic (4.25e-2)" "unprognostic (8.73e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 246.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 343.0" "Group enriched" "Detected in many" 9 "dendritic cells: 143.9;NK-cells: 272.9;T-cells: 255.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 12 "gdT-cell: 1109.8;MAIT T-cell: 1034.8;memory CD4 T-cell: 1123.8;memory CD8 T-cell: 1201.7;naive CD4 T-cell: 1260.7;naive CD8 T-cell: 1168.7;NK-cell: 641.5;T-reg: 1682.7" "Group enriched" "Detected in all" 12 "NK-cells: 641.5;T-cells: 1682.7" "Group enriched" "Detected in some" 6 "JURKAT: 365.7;MOLT-4: 536.9;U-698: 302.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 3.4 2.2 0.4 50.6 0.5 13.7 2.3 0.4 0.5 2.2 0.7 6.9 7.6 1.7 13.0 3.9 2.1 9.4 1.9 0.5 0.4 3.8 3.8 11.4 111.0 0.8 0.5 1.6 0.9 0.5 0.8 1.1 0.6 2.8 6.5 0.0 4.8 1.4 1.3 1.9 23.1 2.3 0.6 39.9 12.1 1.1 0.5 343.0 3.7 1.4 79.6 13.2 2.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.7 64.1 3.5 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.6 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 365.7 0.2 0.0 0.0 0.0 536.9 0.2 5.9 4.6 0.3 20.6 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.3 0.3 0.4 0.6 0.4 0.0 0.0 1.7 0.1 0.1 0.7 0.3 302.7 0.0 0.1 0.0 12.8 5.2 6.0 1109.8 4.9 1034.8 62.0 1123.8 1201.7 5.2 98.9 1260.7 1168.7 33.6 641.5 6.0 7.7 1682.7 1836.9 0.4 0.5 0.4 0.5 0.5 0.4 0.8 0.5 0.6 0.6 0.5 0.6 4.9 0.0 9.3 0.0 23.4 4.6 1.2 0.4 0.0 0.0 3.5 5.2 1.8 4.3 1.6 3.7 0.0 0.3 143.9 0.9 0.0 0.6 0.1 1.0 0.5 3.4 2.4 10.1 0.2 0.5 0.2 3.1 7.7 0.7 5.1 0.0 4.6 1.5 0.3 0.0 0.2 0.3 0.0 7.8 7.3 0.0 0.0 8.1 3.6 0.0 8.7 0.0 272.9 0.5 0.1 4.7 0.0 0.4 15.7 1.0 0.0 1.4 1.8 0.0 0.0 1.5 2.4 4.5 2.0 0.5 3.1 0.4 255.5 2.9 1.3 1.1 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 438.4;granulocytes: 309.1;Hofbauer cells: 264.4;Kupffer cells: 401.2;Langerhans cells: 337.6;Late spermatids: 290.9;Macrophages: 466.1;monocytes: 535.7;NK-cells: 471.7;T-cells: 375.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 875.8;HDLM-2: 799.3;HL-60: 850.7;HMC-1: 861.7;JURKAT: 792.7;NB-4: 789.2;THP-1: 840.5;U-698: 1105.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 85.9 31.1 11.3 396.9 13.1 709.0 43.9 13.9 30.9 28.5 16.8 54.7 42.4 27.4 402.7 29.5 21.5 76.4 14.5 11.3 14.2 13.1 89.0 173.8 563.5 19.7 18.9 10.0 12.2 12.6 4.3 67.2 21.3 184.5 71.2 4.9 44.4 24.3 7.1 40.6 62.3 60.4 18.6 375.2 53.2 33.2 24.8 499.8 23.6 17.8 605.1 133.0 7.7 29.9 36.1 0.2 1.9 0.0 0.0 0.0 409.8 0.1 1.2 3.9 2.9 237.4 1.4 875.8 179.5 0.0 249.1 1.7 0.1 0.6 3.9 799.3 202.9 187.6 0.4 1.1 0.9 850.7 861.7 2.3 0.1 1.4 1.2 0.3 0.0 792.7 100.4 569.7 0.0 2.8 624.8 789.2 1.0 0.4 8.2 451.6 1.6 638.2 0.0 233.8 2.8 7.5 1.9 91.8 6.4 25.0 6.4 840.5 3.1 22.0 13.6 1.5 25.5 135.3 292.5 1105.7 17.0 530.9 3.6 1007.3 1559.5 810.8 915.7 1806.2 822.0 342.3 539.6 761.2 1134.5 251.6 330.2 560.5 1908.6 650.6 1826.1 297.5 598.1 3644.2 11.3 13.1 13.9 30.9 11.3 14.2 19.7 18.9 21.3 18.6 24.8 29.9 7.4 32.1 73.2 0.3 185.2 12.0 1.2 0.0 1.8 0.4 10.3 11.7 4.2 5.7 18.0 3.7 0.0 9.8 438.4 0.2 0.0 16.9 113.1 4.7 42.8 9.6 1.2 63.9 0.5 16.3 68.3 10.9 19.9 7.0 309.1 0.7 12.5 24.0 264.4 0.0 0.5 0.5 0.0 401.2 337.6 290.9 1.2 466.1 23.2 17.8 535.7 23.7 471.7 0.5 1.5 6.8 2.4 1.9 102.4 42.0 0.1 1.5 13.8 1.2 0.0 3.1 6.2 2.7 1.6 2.2 11.8 13.5 375.3 0.5 0.4 4.0 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116780 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.6;liver: 135.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.3;Distal enterocytes: 80.2;Distal tubular cells: 37.2;Hepatocytes: 88.6;Proximal tubular cells: 118.1" "Cancer enhanced" "Detected in all" "liver cancer: 32.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.1" "Group enriched" "Detected in many" 45 "granulocytes: 11.1;monocytes: 4.8" "Cell line enhanced" "Detected in many" "Hep G2: 11.4;HMC-1: 14.4;T-47d: 29.1;U-266/70: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041766, HPA048639, HPA066148" Enhanced Approved Cytosol No NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041766: AB_2677660, HPA048639: AB_2680473, HPA066148: AB_2685626" "unprognostic (8.75e-2)" "unprognostic (3.68e-3)" "unprognostic (1.27e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "prognostic favorable (5.61e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.74e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-14)" "unprognostic (4.10e-3)" "unprognostic (4.49e-2)" "unprognostic (7.00e-2)" "unprognostic (2.20e-1)" 24.9 14.4 17.7 2.1 19.7 0.7 11.7 20.5 22.6 5.4 34.1 27.2 8.8 3.5 1.1 10.8 5.5 3.0 85.6 16.1 18.9 36.1 135.5 4.9 0.8 20.8 20.2 16.4 18.7 17.0 11.8 0.7 22.4 8.1 9.7 1.3 21.3 3.2 68.7 5.8 5.7 1.2 17.0 1.1 23.1 1.7 19.3 0.5 10.6 52.7 0.6 2.6 3.7 17.5 0.7 2.1 0.0 0.2 1.6 1.4 6.1 0.2 0.1 0.2 0.2 2.8 2.6 0.1 2.1 0.9 1.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.8 11.4 2.6 0.0 14.4 2.0 0.3 0.0 0.0 0.6 0.1 0.4 0.7 2.5 0.0 5.3 0.1 0.8 1.4 2.7 1.3 0.0 0.0 7.8 1.4 0.1 0.0 0.0 0.2 5.2 0.3 0.7 29.1 3.3 0.0 0.0 0.2 0.0 0.0 11.5 0.6 0.0 1.9 0.1 0.0 11.1 2.2 0.6 0.0 3.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 17.7 19.7 20.5 22.6 16.1 18.9 20.8 20.2 22.4 17.0 19.3 17.5 1.6 0.0 6.7 7.8 1.0 0.6 1.8 2.2 0.6 0.5 6.5 2.4 37.3 11.5 2.3 11.0 0.0 2.1 0.1 80.2 37.2 2.3 0.4 2.2 0.3 1.7 3.0 2.7 1.0 6.2 1.2 2.3 32.6 3.8 10.2 2.1 4.2 88.6 7.2 1.7 1.4 11.0 0.0 6.0 1.0 0.6 0.0 3.0 5.4 1.9 2.0 12.0 0.0 1.0 3.2 3.0 28.3 0.0 0.8 2.1 2.4 118.1 2.0 1.4 0.0 4.1 1.3 0.0 0.7 3.6 0.3 3.1 1.0 1.8 15.7 1.5 LEF1 "TCF10, TCF1ALPHA, TCF7L3" ENSG00000138795 "Lymphoid enhancer binding factor 1" Q9UJU2 4 108047545-108168956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lymphoid tissue: 349.2" "Cell type enhanced" "Detected in many" "Melanocytes: 33.8;Microglial cells: 145.2;T-cells: 70.3" "Cancer enhanced" "Detected in all" "melanoma: 25.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 142.6" "Lineage enriched" "Detected in many" 4 "T-cells: 142.6" "Group enriched" "Detected in many" 5 "JURKAT: 579.6;MOLT-4: 569.0;REH: 454.8" "Region enhanced" "Detected in all" "thalamus: 22.6" "Low region specificity" "Detected in all" "HPA002087, CAB019405" Enhanced Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "CAB019405: AB_823558, HPA002087: AB_1079245" "unprognostic (1.03e-3)" "unprognostic (7.36e-3)" "unprognostic (2.97e-2)" "prognostic favorable (1.37e-5)" "unprognostic (9.08e-2)" "unprognostic (5.24e-2)" "unprognostic (3.81e-2)" "unprognostic (1.10e-2)" "unprognostic (1.77e-1)" "unprognostic (5.21e-2)" "unprognostic (9.99e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.47e-6)" "unprognostic (1.12e-1)" "unprognostic (5.22e-2)" "unprognostic (7.88e-2)" "unprognostic (8.91e-2)" 1.0 12.7 10.7 13.8 7.6 11.6 2.0 6.1 7.9 4.2 14.3 1.5 0.7 8.0 4.8 3.2 5.1 3.9 0.2 5.7 9.9 2.5 0.3 3.3 31.3 8.9 11.2 1.1 0.1 0.3 1.0 11.0 9.4 3.7 1.4 0.5 1.0 1.0 0.1 2.8 4.1 3.9 5.9 9.8 1.5 12.3 18.2 349.2 3.0 0.1 22.8 5.5 3.0 5.5 0.1 0.0 8.0 0.0 0.0 0.0 0.0 0.2 7.2 1.8 4.7 27.1 0.0 0.0 0.1 0.0 2.5 0.2 7.9 0.0 3.7 0.3 17.6 6.9 0.0 0.0 0.0 23.6 2.9 0.4 0.4 0.0 0.7 3.5 0.0 579.6 14.2 0.0 2.6 1.0 569.0 0.0 1.7 6.3 1.4 454.8 9.1 0.2 2.4 1.3 3.0 5.2 0.0 0.5 83.8 6.7 2.4 0.2 0.0 11.9 10.3 0.0 15.3 38.3 17.0 100.9 7.8 0.0 48.4 0.3 0.2 0.0 8.2 0.0 1.6 0.6 68.3 29.9 0.1 0.9 142.6 102.2 1.9 32.9 0.3 0.5 97.7 36.8 10.7 7.6 6.1 7.9 5.7 9.9 8.9 11.2 9.4 5.9 18.2 5.5 1.4 3.2 1.9 2.0 4.4 3.3 1.4 1.0 24.5 0.1 0.4 5.0 1.6 0.0 0.7 0.0 0.0 0.1 6.2 0.0 13.7 0.0 4.2 5.8 22.3 22.0 0.0 9.2 0.2 0.0 0.2 2.1 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.2 4.1 0.3 1.4 7.9 0.6 2.0 33.8 145.2 3.5 0.6 10.3 0.5 0.6 0.1 0.0 0.0 5.4 1.8 0.0 0.5 2.3 0.3 0.0 0.6 9.0 16.1 6.6 11.3 1.3 0.4 70.3 0.0 0.9 0.4 LEO1 ENSG00000166477 "LEO1 homolog, Paf1/RNA polymerase II complex component" Q8WVC0 15 51938025-51971778 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 7 "granulocytes: 272.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040741, HPA040941" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Centrosome" No No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Nucleoli fibrillar center" Centrosome "HPA040741: AB_10794859, HPA040941: AB_10805832" "unprognostic (2.76e-2)" "unprognostic (2.14e-2)" "unprognostic (2.44e-1)" "unprognostic (1.81e-3)" "unprognostic (2.85e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-2)" "unprognostic (1.04e-2)" "unprognostic (1.83e-2)" "unprognostic (2.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (8.48e-2)" "unprognostic (2.10e-2)" "unprognostic (1.08e-1)" 10.2 11.4 8.1 13.8 8.8 9.0 15.5 14.7 12.9 11.6 6.4 17.0 13.3 10.4 10.0 19.8 8.7 13.2 8.1 8.0 10.0 13.7 22.2 9.7 18.0 8.0 8.1 8.5 8.1 18.8 9.1 12.1 7.7 12.3 19.2 12.0 18.5 8.6 13.9 20.8 14.5 11.7 6.9 10.5 13.2 9.3 8.3 22.1 11.1 11.7 17.9 19.3 14.0 10.0 28.0 63.9 40.3 32.6 40.7 35.0 28.8 44.4 36.6 37.3 33.9 44.3 17.9 56.2 25.3 45.8 41.3 53.2 54.2 39.6 35.8 37.5 24.5 88.5 50.6 78.5 32.0 80.7 118.2 37.9 30.5 29.2 37.6 35.2 37.0 46.5 54.6 30.1 44.9 118.7 43.0 61.1 17.4 82.6 27.0 47.6 69.7 58.9 32.8 77.0 28.5 43.4 33.9 51.5 36.5 43.8 42.8 72.6 44.4 36.8 25.5 34.3 53.7 23.4 78.2 50.7 32.2 113.1 40.0 11.5 14.5 15.7 27.4 23.3 25.7 18.7 27.2 22.3 23.8 16.4 27.9 25.2 3.3 30.9 26.0 17.8 31.7 16.3 8.1 8.8 14.7 12.9 8.0 10.0 8.0 8.1 7.7 6.9 8.3 10.0 16.2 35.3 24.6 10.1 15.2 26.1 16.8 33.4 18.2 38.2 11.8 10.2 21.2 17.2 37.0 7.3 10.4 24.9 24.8 24.6 15.6 26.3 2.4 19.5 38.8 18.0 7.7 12.4 16.5 24.2 26.7 19.9 15.8 29.8 272.8 16.2 10.0 18.0 19.5 26.9 16.9 17.9 26.4 14.8 6.0 2.7 8.1 13.0 3.6 5.6 12.8 23.1 22.6 13.0 13.3 18.2 14.7 13.5 11.0 9.0 20.5 23.3 31.4 23.2 6.6 18.5 29.3 21.5 11.0 19.5 24.7 17.6 25.0 23.8 17.0 21.2 LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241278-128257629 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "adipose tissue: 307.5;breast: 90.1" "Group enriched" "Detected in some" 44 "Extravillous trophoblasts: 124.2;Syncytiotrophoblasts: 432.2" "Cancer enhanced" "Detected in some" "breast cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.1;SuSa: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" CAB010490 Approved "Secreted to blood" NA NA 17000000 19000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB010490: AB_2296951" "unprognostic (8.19e-3)" "unprognostic (5.33e-1)" "unprognostic (1.60e-4)" "unprognostic (1.19e-1)" "unprognostic (7.99e-3)" "unprognostic (1.83e-1)" "unprognostic (6.56e-3)" "unprognostic (1.98e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.23e-2)" "unprognostic (6.84e-2)" 307.5 0.8 0.1 5.0 0.1 0.1 90.1 0.5 0.3 0.1 0.1 2.0 0.1 0.0 0.0 0.2 0.1 1.2 1.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 2.4 0.0 0.0 4.6 0.1 0.0 0.4 0.0 1.1 0.0 0.7 3.9 1.2 0.1 0.0 0.2 0.5 0.2 0.1 0.3 0.2 1.2 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.8 0.1 0.6 0.3 0.0 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 124.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.0 0.1 432.2 0.1 0.1 0.0 0.1 LEXM "C1orf177, FLJ40201, LEM" ENSG00000162398 "Lymphocyte expansion molecule" Q3ZCV2 1 54806063-54842252 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 12.7;testis: 4.8;vagina: 4.0" "Group enriched" "Detected in some" 5 "Early spermatids: 37.7;Late spermatids: 46.0" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035889, HPA035890" Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "HPA035889: AB_2674844, HPA035890: AB_10669535" "unprognostic (1.61e-1)" "unprognostic (2.18e-2)" "unprognostic (5.01e-2)" "unprognostic (3.69e-2)" "unprognostic (1.50e-2)" "unprognostic (8.32e-2)" "unprognostic (7.28e-2)" "unprognostic (1.81e-1)" "unprognostic (1.41e-1)" "unprognostic (5.13e-3)" "unprognostic (1.29e-1)" "unprognostic (1.03e-4)" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (3.64e-1)" "unprognostic (1.81e-1)" 0.0 0.1 0.1 0.0 1.6 0.1 0.1 0.1 0.9 1.5 0.0 0.4 1.6 0.0 0.1 12.7 0.1 0.0 0.0 0.1 0.2 0.1 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.7 0.0 0.0 1.0 1.3 0.0 0.0 0.1 0.2 4.8 0.1 0.0 0.0 0.0 0.5 0.0 4.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 3.8 0.0 0.2 0.0 0.8 2.0 0.0 0.0 0.1 2.5 0.0 2.0 0.0 0.1 0.2 1.0 0.1 1.6 0.1 0.9 0.1 0.2 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 37.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 46.0 0.3 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.1 0.0 0.7 0.3 0.0 4.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.6 0.6 0.0 0.0 1.0 0.0 0.6 0.2 LFNG SCDO3 ENSG00000106003 "LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q8NES3 7 2512529-2529177 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 74.4" "Cell type enhanced" "Detected in many" "dendritic cells: 40.3;Enteroendocrine cells: 87.4;monocytes: 38.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 37.7;OE19: 46.4;RH-30: 46.0;U-2 OS: 49.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069130 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" NA NA 880000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "Nuclear membrane" "HPA069130: AB_2686091" "unprognostic (4.58e-2)" "unprognostic (1.17e-2)" "unprognostic (2.52e-2)" "prognostic favorable (6.36e-4)" "unprognostic (1.85e-2)" "unprognostic (8.34e-2)" "unprognostic (4.15e-1)" "unprognostic (7.86e-2)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.89e-1)" "unprognostic (5.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.09e-1)" "unprognostic (1.97e-2)" "unprognostic (2.28e-2)" 16.7 6.5 23.3 17.3 25.9 9.8 13.7 29.3 22.4 9.9 11.1 23.1 15.5 9.4 2.2 11.4 6.1 11.8 13.1 17.4 30.1 9.0 2.5 14.4 18.6 34.1 35.6 1.8 74.4 3.0 3.7 6.5 24.8 17.1 12.0 3.0 33.4 4.6 4.6 58.2 17.2 5.8 25.0 20.9 37.8 4.2 38.1 5.8 6.7 3.6 10.8 12.2 13.8 23.6 1.5 14.3 18.4 2.5 2.0 1.7 1.2 5.4 2.8 4.7 5.9 6.0 37.7 1.1 16.7 14.8 8.1 27.1 2.9 5.1 2.3 8.6 0.6 4.3 7.7 3.2 0.1 6.2 7.7 3.3 12.6 7.8 0.8 3.2 1.9 0.3 0.7 0.2 3.6 34.5 0.1 8.7 22.4 46.4 10.3 1.8 46.0 2.9 1.8 4.5 16.9 4.2 6.2 1.4 0.3 4.7 10.2 7.3 4.5 10.5 49.7 0.4 15.4 0.2 0.0 1.4 11.8 16.4 2.0 6.3 5.3 12.7 1.8 6.9 2.0 1.1 1.7 0.9 2.3 2.0 1.8 1.8 2.8 1.3 6.6 0.6 4.2 1.7 23.3 25.9 29.3 22.4 17.4 30.1 34.1 35.6 24.8 25.0 38.1 23.6 23.3 6.4 6.0 18.9 15.6 6.8 2.5 10.6 3.4 8.5 5.3 12.4 3.6 5.7 2.8 0.0 0.0 0.1 40.3 23.1 0.0 1.2 0.1 2.4 8.5 16.0 87.4 2.7 0.0 6.4 0.3 5.7 30.5 1.2 17.7 0.1 13.9 0.6 7.0 0.0 0.1 34.5 6.1 30.4 13.8 0.5 1.8 30.6 3.6 11.2 38.2 31.3 19.6 1.5 0.1 21.7 3.1 0.0 12.6 2.2 8.8 0.4 1.2 0.8 0.0 0.6 5.0 0.3 3.1 0.6 4.0 0.0 15.9 0.5 15.3 0.7 LGALS12 GRIP1 ENSG00000133317 "Galectin 12" Q96DT0 11 63506052-63516774 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 78.3;breast: 41.3" "Cell type enhanced" "Detected in some" "granulocytes: 17.8;Macrophages: 13.3;monocytes: 2.5;Muller glia cells: 3.9" "Cancer enhanced" "Detected in some" "renal cancer: 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 20 "eosinophil: 554.9" "Lineage enriched" "Detected in many" 20 "granulocytes: 554.9" "Group enriched" "Detected in some" 14 "ASC diff: 28.9;HL-60: 53.0;NB-4: 109.4;U-937: 112.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA021124 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA021124: " "unprognostic (3.89e-2)" "unprognostic (4.40e-2)" "unprognostic (5.17e-2)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "unprognostic (4.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.31e-2)" "unprognostic (1.01e-1)" "unprognostic (2.13e-3)" "unprognostic (4.69e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (4.60e-7)" "unprognostic (2.72e-3)" "unprognostic (1.19e-1)" "unprognostic (6.22e-2)" "unprognostic (8.60e-2)" 78.3 0.8 0.1 2.7 0.2 18.4 41.3 0.1 0.2 0.1 0.4 0.9 0.5 0.2 0.0 0.2 1.0 1.7 2.1 0.1 0.2 0.3 0.3 1.0 0.1 0.2 0.2 0.2 0.6 0.0 0.0 0.1 0.2 0.4 0.6 1.9 4.5 0.7 0.5 1.0 2.0 1.0 0.2 1.1 0.9 0.0 0.1 0.3 0.7 1.4 0.0 1.0 0.3 0.2 0.0 0.0 0.0 0.0 28.9 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.8 53.0 3.3 3.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 109.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 5.3 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 112.2 0.0 15.5 28.1 554.9 0.2 3.3 0.2 0.0 0.0 0.0 7.5 0.1 0.1 0.1 5.7 0.2 0.5 0.7 0.3 17.3 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 17.8 0.0 1.1 0.1 1.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 13.3 0.0 0.0 2.5 3.9 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 LGALS7B GAL7 ENSG00000178934 "Galectin 7B" P47929 19 38789200-38791754 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6695.7" "Group enriched" "Detected in many" 10 "Basal keratinocytes: 1529.6;Suprabasal keratinocytes: 5136.5" "Cancer enhanced" "Detected in many" "cervical cancer: 142.7;head and neck cancer: 185.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HaCaT: 3.9;OE19: 3.9" "HPA001549, CAB025100" Supported "Intracellular and membrane" NA NA 4000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "CAB025100: , HPA001549: AB_1078938" "unprognostic (4.20e-2)" "unprognostic (2.15e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.81e-1)" "unprognostic (3.54e-2)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (5.92e-2)" "unprognostic (3.66e-3)" "unprognostic (6.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.20e-2)" "unprognostic (1.29e-3)" 6.1 1.0 0.0 0.0 0.0 0.1 7.3 0.0 0.0 490.5 0.0 1.8 0.0 1.0 0.0 1463.3 0.9 0.0 2.6 0.0 0.0 2.1 3.0 2.6 0.0 0.0 0.0 1.4 2.7 0.0 2.2 0.0 0.0 5.0 0.0 0.0 167.2 0.1 10.2 6695.7 1.7 0.0 0.0 22.0 3.0 4.9 0.0 0.2 2.3 0.0 1.6 1.0 834.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1529.6 6.3 253.5 102.4 0.0 1.2 13.3 0.4 0.0 64.4 1.8 0.0 0.0 0.0 0.3 0.0 0.0 5.4 3.1 0.2 3.2 1.2 0.0 0.0 0.2 0.1 3.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 41.3 12.3 0.0 0.3 44.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 2.1 0.3 0.3 9.3 0.0 0.0 1.3 4.2 7.5 1.9 329.6 5136.5 0.0 1.6 0.4 0.1 14.0 LGI4 ENSG00000153902 "Leucine rich repeat LGI family member 4" Q8N135 19 35124513-35142451 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.7;Distal enterocytes: 33.1;Muller glia cells: 95.5;Sertoli cells: 78.9;Smooth muscle cells: 104.4" "Group enriched" "Detected in many" 6 "glioma: 4.5;melanoma: 11.5;renal cancer: 13.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 27 "WM-115: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042116, HPA043556" Approved Approved "Golgi apparatus" "Secreted in brain" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "HPA042116: AB_2677855, HPA043556: AB_2678550" "unprognostic (3.79e-1)" "unprognostic (6.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-2)" "unprognostic (3.71e-2)" "unprognostic (2.12e-2)" "unprognostic (4.26e-2)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.84e-7)" "unprognostic (1.71e-2)" "unprognostic (4.47e-1)" "unprognostic (7.73e-2)" "unprognostic (7.13e-2)" 77.6 5.4 71.2 4.1 72.3 0.2 36.1 70.3 98.4 99.9 52.1 100.5 3.6 35.5 2.3 15.0 43.7 5.0 39.4 67.8 61.3 4.7 8.0 14.3 2.1 86.5 68.4 13.3 6.4 1.4 4.4 3.6 70.1 37.2 3.7 7.2 12.2 13.3 39.1 21.2 35.1 4.8 72.8 1.9 27.0 2.7 72.0 0.5 19.1 5.4 0.5 33.5 79.3 81.4 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.1 30.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 71.2 72.3 70.3 98.4 67.8 61.3 86.5 68.4 70.1 72.8 72.0 81.4 13.3 0.0 0.0 74.7 0.2 2.5 0.6 0.3 3.4 0.8 1.5 1.5 17.1 0.0 0.8 1.8 2.1 0.0 0.2 33.1 0.0 0.0 0.1 0.2 2.8 5.4 1.8 0.0 21.9 0.0 0.3 12.7 0.0 0.2 0.0 0.0 7.9 2.0 0.1 0.0 2.2 0.9 0.0 0.0 4.6 0.3 14.6 0.7 10.6 5.6 0.1 95.5 0.0 2.0 9.2 0.1 21.8 7.2 0.3 1.2 1.1 0.1 0.9 3.1 78.9 7.9 104.4 2.8 2.8 0.8 2.4 0.0 0.7 0.0 0.7 1.1 LGR4 GPR48 ENSG00000205213 "Leucine rich repeat containing G protein-coupled receptor 4" Q9BXB1 11 27365961-27472790 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, Immunity, Innate immunity, Spermatogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 204.4;Distal enterocytes: 123.3;Glandular and luminal cells: 137.7;Syncytiotrophoblasts: 128.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 83.5;RPTEC TERT1: 100.4;U-2197: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030267, HPA054350" Uncertain Approved "Centriolar satellite" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" "HPA030267: AB_10610004, HPA054350: " "unprognostic (5.27e-3)" "unprognostic (5.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.59e-1)" "unprognostic (4.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "unprognostic (2.00e-2)" "unprognostic (4.63e-2)" "unprognostic (5.84e-3)" "unprognostic (2.10e-1)" "prognostic favorable (2.00e-7)" "unprognostic (5.01e-1)" "unprognostic (3.59e-1)" "unprognostic (3.54e-2)" "unprognostic (1.76e-1)" 16.4 16.8 10.2 8.1 10.2 2.4 16.1 13.0 9.2 7.5 10.2 36.8 22.6 10.2 13.3 13.7 10.2 9.0 19.4 7.8 10.5 51.5 55.7 3.2 1.5 14.1 10.4 22.9 59.7 6.4 6.8 34.4 12.8 15.4 36.8 44.4 18.1 16.1 14.4 18.3 24.7 13.2 13.4 11.7 31.0 13.9 10.1 4.4 15.2 8.2 3.0 10.1 11.7 18.0 28.3 50.7 49.5 5.7 4.5 3.1 56.0 15.7 14.8 13.8 11.8 7.6 0.5 0.1 10.1 21.2 23.2 45.8 83.5 31.1 23.5 0.2 37.0 15.3 28.4 36.1 1.4 1.6 0.1 4.1 19.5 9.5 21.0 57.0 7.0 0.0 4.5 0.1 5.7 9.0 0.1 2.7 47.9 76.3 20.4 0.2 33.8 3.3 100.4 12.1 0.7 6.0 7.7 45.7 4.6 37.6 15.1 23.4 22.6 10.2 8.2 82.6 14.6 18.9 15.2 0.0 17.3 0.0 6.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 10.2 13.0 9.2 7.8 10.5 14.1 10.4 12.8 13.4 10.1 18.0 1.7 3.2 0.5 204.4 1.4 30.3 13.5 33.1 38.7 18.6 17.2 14.1 26.6 24.3 15.4 44.1 25.0 55.1 0.4 123.3 3.9 21.4 7.1 75.4 11.5 3.9 16.8 3.4 35.6 50.7 29.2 14.5 43.3 137.7 0.0 78.6 3.6 60.7 8.1 25.2 51.6 47.1 20.3 5.3 5.7 2.2 5.0 1.6 7.2 15.0 2.1 109.8 0.0 36.7 62.1 31.4 48.8 17.0 0.6 11.7 37.9 19.4 14.5 14.8 6.6 6.9 13.0 1.3 1.4 36.8 21.9 128.6 1.8 6.3 55.5 19.7 LHPP HDHD2B ENSG00000107902 "Phospholysine phosphohistidine inorganic pyrophosphate phosphatase" Q9H008 10 124461823-124617888 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 198.8;choroid plexus: 104.0" "Cell type enhanced" "Detected in many" "Early spermatids: 114.9;Late spermatids: 163.3;Proximal tubular cells: 93.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009163, HPA009269" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 820000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Cytosol" "HPA009163: AB_1079250, HPA009269: AB_1079249" "unprognostic (3.46e-2)" "unprognostic (1.23e-2)" "unprognostic (4.78e-2)" "unprognostic (3.89e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-1)" "unprognostic (5.77e-3)" "unprognostic (2.02e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (6.42e-2)" "unprognostic (5.55e-2)" "unprognostic (1.79e-3)" "unprognostic (2.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" 12.9 32.0 135.1 8.2 173.7 10.5 13.0 159.3 190.6 18.5 104.0 27.1 23.4 20.2 13.4 24.1 10.0 10.2 17.5 129.7 156.5 28.4 60.2 9.2 11.8 179.2 165.8 9.0 15.9 9.2 14.5 8.6 170.7 14.0 8.5 7.5 18.3 12.5 10.2 15.3 21.1 10.2 151.1 14.0 20.1 24.2 156.3 9.7 29.4 4.8 15.2 14.7 16.1 198.8 24.7 12.0 4.7 12.1 18.2 14.7 12.8 8.2 18.0 5.5 10.0 2.1 22.4 24.4 19.7 13.5 6.1 26.1 1.4 4.7 5.7 5.4 16.3 17.6 4.1 11.4 18.5 3.6 27.6 11.0 20.0 5.4 13.0 16.0 8.8 21.4 8.9 9.5 6.9 24.5 12.0 11.3 8.5 10.4 6.8 12.4 5.3 31.8 12.1 3.2 2.7 14.2 6.3 22.6 8.2 6.5 17.2 0.6 4.2 8.5 12.2 7.2 2.3 7.9 2.5 7.8 7.7 6.8 2.0 8.1 28.8 25.3 16.1 24.5 20.8 41.0 18.7 17.2 35.6 43.3 22.4 16.0 4.8 7.9 29.0 13.4 32.1 24.4 135.1 173.7 159.3 190.6 129.7 156.5 179.2 165.8 170.7 151.1 156.3 198.8 5.0 3.2 14.8 22.9 29.1 7.4 9.4 22.1 13.1 6.0 19.8 19.8 15.8 12.8 19.4 7.3 0.0 54.2 6.2 17.9 33.2 5.3 114.9 17.7 12.7 4.6 9.5 19.8 29.4 2.3 24.7 11.2 19.9 8.2 10.8 23.3 6.1 61.1 26.5 11.8 27.8 21.3 24.4 16.0 8.1 163.3 5.9 12.9 17.8 8.4 15.6 9.8 8.2 15.6 76.4 3.3 30.2 10.5 19.7 6.7 80.5 93.8 24.9 6.4 13.1 5.2 9.5 33.1 11.3 30.7 5.4 24.2 12.1 12.4 23.0 16.3 LHX2 "hLhx2, LH-2" ENSG00000106689 "LIM homeobox 2" P50458 9 124001670-124033301 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 99.8;choroid plexus: 48.5;retina: 34.1" "Cell type enhanced" "Detected in some" "Astrocytes: 68.6;Early spermatids: 43.1;Muller glia cells: 254.6" "Group enriched" "Detected in many" 5 "cervical cancer: 3.2;glioma: 10.7;melanoma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 23.2;GAMG: 17.9;HAP1: 23.5;HeLa: 15.5;NTERA-2: 28.5;U-138 MG: 14.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000838 Supported Approved Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA000838: AB_2666109" "unprognostic (3.60e-3)" "prognostic favorable (9.52e-4)" "unprognostic (3.52e-1)" "unprognostic (9.97e-2)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (6.37e-3)" "unprognostic (1.07e-1)" "unprognostic (4.59e-2)" "unprognostic (3.24e-1)" "unprognostic (2.96e-1)" "unprognostic (1.32e-2)" "unprognostic (4.66e-15)" "unprognostic (1.72e-1)" "unprognostic (2.92e-1)" "unprognostic (2.46e-2)" "unprognostic (1.77e-1)" 0.1 0.1 77.8 0.2 78.1 0.0 0.2 48.5 99.8 0.0 48.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 88.1 51.2 0.3 6.7 0.0 0.3 49.5 52.7 0.2 0.0 0.0 9.8 3.4 50.2 0.0 0.1 34.1 0.1 0.0 0.0 6.1 0.2 0.0 48.3 0.1 0.0 3.0 54.9 0.1 0.0 0.0 0.2 0.1 0.0 73.9 0.0 7.2 0.2 23.2 0.0 0.3 2.6 0.7 0.3 1.8 0.2 7.8 0.0 0.2 3.0 1.4 17.9 0.2 23.5 0.0 0.9 0.0 5.0 0.0 15.5 0.4 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 12.1 0.0 0.2 28.5 0.0 7.0 6.5 0.1 0.0 0.0 0.1 9.2 0.1 5.7 0.0 0.0 0.2 8.0 3.1 0.0 14.6 0.6 4.2 1.1 0.4 5.0 0.0 0.8 3.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.8 78.1 48.5 99.8 88.1 51.2 49.5 52.7 50.2 48.3 54.9 73.9 0.1 0.0 0.0 68.6 0.2 0.0 0.0 0.0 0.0 3.2 0.1 0.3 0.6 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.0 0.0 43.1 0.1 0.0 0.3 0.0 0.0 20.6 0.0 8.9 0.1 0.0 0.0 0.0 0.1 3.9 0.0 4.0 8.4 2.5 0.0 0.0 0.0 0.3 21.7 0.0 0.1 0.0 1.9 0.0 254.6 0.0 5.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.4 0.2 4.2 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.0;lymphoid tissue: 49.9" "Group enriched" "Detected in many" 5 "Hofbauer cells: 63.4;Kupffer cells: 88.6;Macrophages: 88.8;monocytes: 71.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.8" "Group enriched" "Detected in many" 4 "granulocytes: 44.8;monocytes: 15.4" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" 9.9 3.4 0.4 8.3 0.4 14.6 2.9 0.4 2.1 1.2 0.9 2.7 0.3 1.2 0.3 1.3 5.4 0.1 3.4 0.4 0.4 2.3 4.1 27.0 0.3 1.2 0.8 1.0 1.9 0.0 1.3 1.2 1.3 1.7 0.0 0.2 2.4 0.0 1.1 0.8 2.6 0.1 0.6 49.9 2.3 0.5 1.8 0.6 1.6 0.0 0.2 3.2 1.6 1.4 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.4 0.6 0.1 14.3 0.2 0.1 0.3 0.0 7.2 0.1 0.0 0.1 44.8 0.0 5.6 0.5 0.0 11.6 0.4 0.4 0.4 2.1 0.4 0.4 1.2 0.8 1.3 0.6 1.8 1.4 1.5 9.6 13.0 0.3 2.2 2.4 1.2 6.5 0.0 0.7 1.6 2.2 0.4 4.3 8.3 1.8 0.0 1.5 2.1 0.6 0.0 0.3 1.3 0.8 1.9 3.0 0.0 0.8 0.2 0.6 6.7 2.9 0.0 2.2 7.6 0.5 1.8 3.2 63.4 0.0 0.1 1.9 0.0 88.6 8.4 4.1 0.3 88.8 1.8 1.9 71.2 0.9 3.1 0.0 0.1 0.2 1.3 0.7 2.1 1.6 0.4 0.4 5.2 2.9 6.6 4.3 1.3 0.8 1.5 0.1 3.0 1.2 3.8 2.6 2.0 0.4 LIN7A "LIN-7A, MALS-1, TIP-33, VELI1" ENSG00000111052 "Lin-7 homolog A, crumbs cell polarity complex component" O14910 12 80792520-80937934 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.9;retina: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 77.3;Early spermatids: 107.2;Excitatory neurons: 135.5;Inhibitory neurons: 93.1;Late spermatids: 76.9;Spermatocytes: 61.3" "Cancer enhanced" "Detected in many" "renal cancer: 8.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 18.8;eosinophil: 15.8;neutrophil: 29.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 29.8" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;ASC TERT1: 31.4;HAP1: 25.2;HDLM-2: 29.6;HL-60: 29.1;NB-4: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071562 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071562: AB_2732181" "unprognostic (7.11e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-3)" "unprognostic (3.04e-2)" "unprognostic (8.24e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-2)" "unprognostic (8.83e-2)" "unprognostic (2.27e-2)" "unprognostic (2.41e-1)" "prognostic favorable (1.63e-11)" "unprognostic (5.01e-5)" "unprognostic (7.79e-2)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" 5.0 3.1 5.5 2.4 6.5 27.9 5.4 22.2 8.0 7.9 1.0 1.9 0.5 8.5 0.5 0.9 3.7 4.0 6.3 6.4 6.0 8.7 17.7 5.1 2.6 1.9 6.9 3.7 0.5 0.9 6.0 5.3 3.1 1.8 0.6 26.6 0.8 0.7 1.0 0.7 2.1 4.6 2.3 4.6 1.1 7.1 6.9 0.7 4.2 2.5 1.2 3.9 4.6 3.6 0.0 0.6 5.0 0.0 21.3 31.4 0.0 12.8 5.9 5.1 1.1 9.9 0.0 0.0 0.0 4.9 0.1 0.0 25.2 0.0 1.5 29.6 7.8 0.0 0.2 15.6 2.6 29.1 0.2 7.8 0.0 0.5 0.5 1.2 4.1 0.0 0.0 0.0 2.3 0.3 0.0 27.0 4.7 0.3 0.1 0.0 18.7 0.0 2.9 4.1 10.2 0.0 0.0 0.0 0.1 0.3 1.1 15.5 0.0 4.0 1.5 2.1 0.1 4.4 0.0 0.0 0.4 0.0 0.2 18.8 5.2 15.8 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 29.8 0.0 0.2 0.0 0.1 1.2 5.5 6.5 22.2 8.0 6.4 6.0 1.9 6.9 3.1 2.3 6.9 3.6 4.8 22.4 5.8 18.6 0.0 0.8 4.8 0.0 0.0 77.3 10.8 3.4 22.8 8.6 0.6 25.8 2.1 0.4 0.2 0.3 9.8 1.3 107.2 1.9 8.9 1.9 1.8 0.4 135.5 0.2 0.1 4.9 0.0 3.5 0.0 0.1 1.8 21.5 2.5 30.3 93.1 0.5 0.0 5.2 0.7 76.9 4.7 4.2 0.0 9.4 6.5 42.6 0.0 23.1 2.7 0.0 1.2 1.5 0.4 2.0 20.1 26.5 0.7 11.2 13.1 5.0 19.2 61.3 1.3 0.0 0.4 0.7 0.6 3.5 1.1 1.8 LINS1 "LINS, MRT27, WINS1" ENSG00000140471 "Lines homolog 1" Q8NG48 15 100559369-100603230 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038578, HPA038579" Approved Approved Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA038578: AB_2676095, HPA038579: AB_10697393" "unprognostic (9.87e-2)" "unprognostic (3.32e-3)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (7.37e-2)" "unprognostic (6.16e-2)" "unprognostic (7.14e-2)" "unprognostic (1.06e-1)" "unprognostic (2.48e-2)" "unprognostic (3.36e-2)" "unprognostic (1.65e-1)" "unprognostic (1.71e-3)" "unprognostic (1.14e-2)" "unprognostic (2.93e-1)" "unprognostic (2.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.28e-2)" 4.2 4.1 2.5 8.3 2.2 5.7 7.7 3.1 3.3 7.2 2.8 5.8 4.1 6.6 9.4 7.0 5.4 4.4 3.1 2.4 1.7 6.0 5.5 6.2 11.5 1.6 1.4 6.4 5.4 6.1 3.5 6.4 1.8 6.1 7.0 6.6 5.1 4.6 4.3 6.9 4.5 6.2 1.1 8.4 6.3 7.6 2.3 9.1 8.4 5.1 10.0 5.8 4.9 2.8 4.4 6.6 8.2 8.2 5.9 8.0 7.5 6.8 7.6 7.6 8.1 6.2 8.4 11.6 3.9 6.2 5.7 18.5 7.8 8.6 7.9 4.0 11.1 10.4 10.7 4.9 4.9 8.9 6.3 7.7 7.4 5.9 9.4 7.6 9.0 6.4 17.3 9.1 4.7 5.7 5.3 7.6 9.6 16.7 8.1 7.8 13.1 10.8 6.6 11.8 4.2 5.5 6.3 6.1 10.2 10.4 10.3 6.7 6.5 9.5 8.5 6.8 8.9 9.7 13.4 10.5 6.1 11.4 7.7 12.4 7.9 11.7 16.3 7.5 23.9 12.7 25.7 18.1 8.4 11.9 35.0 25.1 10.4 15.0 6.7 6.8 17.6 10.5 2.5 2.2 3.1 3.3 2.4 1.7 1.6 1.4 1.8 1.1 2.3 2.8 7.7 19.2 5.9 0.0 16.6 0.0 9.7 0.0 11.4 16.1 11.3 8.3 0.0 5.7 2.5 12.9 18.8 8.8 20.4 4.9 5.9 5.9 10.8 6.6 11.4 5.7 4.9 11.6 0.0 5.1 5.5 7.2 15.3 6.3 1.3 10.3 7.1 7.6 15.3 16.8 0.0 5.8 0.0 6.0 0.0 1.7 12.2 6.9 0.0 0.0 7.9 9.3 26.8 0.0 0.0 5.4 3.2 7.2 12.5 9.0 10.5 4.7 7.3 16.0 13.1 8.5 5.8 20.7 12.9 9.9 0.0 12.4 29.8 18.9 4.8 7.5 LIPE HSL ENSG00000079435 "Lipase E, hormone sensitive type" Q05469 19 42401514-42427388 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid degradation, Lipid metabolism, Steroid metabolism, Sterol metabolism" Hydrolase "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 834.5;breast: 524.7" "Cell type enhanced" "Detected in many" "Adipocytes: 76.1;Early spermatids: 127.8;Late spermatids: 236.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "ASC diff: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006567, CAB017700" Enhanced Supported Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB017700: AB_2135504, HPA006567: AB_2667618" "unprognostic (4.24e-2)" "unprognostic (2.46e-2)" "unprognostic (8.99e-3)" "unprognostic (3.74e-2)" "unprognostic (1.77e-1)" "unprognostic (3.38e-3)" "unprognostic (5.68e-2)" "unprognostic (2.84e-1)" "unprognostic (3.11e-1)" "unprognostic (9.44e-2)" "prognostic favorable (1.15e-4)" "unprognostic (1.52e-1)" "unprognostic (3.63e-10)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.76e-2)" "unprognostic (2.34e-3)" 834.5 45.1 22.7 7.7 71.7 5.0 524.7 77.2 41.5 5.1 0.6 10.9 5.3 6.4 1.2 8.6 5.8 3.7 32.5 23.8 42.6 7.7 1.5 3.7 7.3 100.3 73.9 4.9 6.2 4.7 6.9 2.9 90.0 7.1 1.4 2.0 17.2 2.6 19.7 23.6 24.4 2.6 44.0 14.4 8.5 68.6 57.1 6.9 9.6 23.3 3.7 14.2 7.7 116.9 12.7 9.6 6.0 2.3 136.8 1.3 0.1 5.8 3.1 9.2 8.5 2.3 4.6 20.6 6.3 1.8 4.5 5.6 3.7 11.5 1.0 4.0 6.1 5.8 5.3 0.2 2.7 0.1 13.9 1.2 10.7 1.5 2.1 1.3 2.6 8.5 2.7 12.8 1.2 0.1 14.8 0.5 0.8 9.7 2.7 12.2 1.1 6.9 2.6 13.1 8.5 8.8 5.1 5.7 5.6 0.3 1.5 7.5 4.7 2.5 7.8 1.1 5.3 9.7 8.5 15.6 6.3 0.7 8.7 11.0 8.6 3.8 2.5 4.7 2.3 3.4 3.2 3.7 3.6 4.5 2.8 2.5 1.5 3.6 2.7 2.9 3.0 3.1 22.7 71.7 77.2 41.5 23.8 42.6 100.3 73.9 90.0 44.0 57.1 116.9 76.1 0.0 3.3 4.2 8.1 4.1 12.1 2.4 4.6 11.0 4.8 2.9 2.5 0.0 2.0 1.8 10.4 0.1 4.8 1.3 1.9 8.0 127.8 0.9 3.4 10.2 0.0 5.3 4.6 2.7 0.1 2.0 3.6 1.5 0.0 6.6 17.9 0.0 0.6 8.4 6.7 2.0 6.1 2.2 2.4 236.5 3.1 0.8 5.4 4.7 0.9 4.0 6.2 6.0 37.9 1.8 0.7 1.5 3.0 6.7 18.4 1.5 0.8 13.9 0.0 7.2 2.1 39.4 13.1 2.5 2.4 0.0 5.1 5.2 2.9 10.7 LIPK "bA186O14.2, LIPL2" ENSG00000204021 "Lipase family member K" Q5VXJ0 10 88724544-88752756 "Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 32.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SK-BR-3: 2.6" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 8: SK-BR-3 - Unknown function" "unprognostic (7.65e-2)" "unprognostic (8.64e-2)" "unprognostic (3.57e-2)" "unprognostic (3.19e-7)" "unprognostic (1.25e-1)" "unprognostic (1.60e-2)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 LIPN "bA186O14.3, LIPL4" ENSG00000204020 "Lipase family member N" Q5VXI9 10 88759982-88779626 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase Ichthyosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "skin 1: 26.7" "Group enriched" "Detected in some" 4 "Macrophages: 7.5;monocytes: 2.5" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 2.9;eosinophil: 10.3;intermediate monocyte: 7.5;neutrophil: 5.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 8 "granulocytes: 10.3;monocytes: 8.5" "Cell line enhanced" "Detected in single" "HL-60: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.27e-1)" "unprognostic (1.07e-1)" "unprognostic (2.03e-2)" "unprognostic (9.75e-2)" "unprognostic (2.54e-2)" "unprognostic (4.40e-2)" "unprognostic (5.77e-3)" "unprognostic (1.65e-1)" 1.3 0.3 0.0 2.8 0.0 2.8 1.7 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 26.7 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 2.9 10.3 0.0 7.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 5.4 0.0 8.5 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 7.5 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 LMNB1 ENSG00000113368 "Lamin B1" P20700 5 126776623-126837020 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.0;lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Early spermatids: 92.5;Erythroid cells: 67.3;Extravillous trophoblasts: 68.2;granulocytes: 93.6;Late spermatids: 72.1;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005269, HPA050524, CAB079757, CAB079954" Supported Supported "Nuclear membrane" NA NA 2100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "CAB005269: AB_648156, CAB079757: AB_2665863, CAB079954: , HPA050524: AB_2681156" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" "unprognostic (4.96e-3)" "unprognostic (3.70e-2)" "unprognostic (1.61e-1)" "unprognostic (8.65e-3)" "prognostic unfavorable (3.08e-6)" "unprognostic (2.06e-2)" "unprognostic (6.62e-3)" "unprognostic (5.28e-2)" "unprognostic (2.13e-3)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.33e-2)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "unprognostic (2.55e-1)" 4.2 1.6 1.9 26.6 1.8 34.0 2.9 9.8 2.1 3.7 0.5 14.9 11.2 2.8 0.5 14.2 1.8 3.4 1.5 1.6 3.3 3.5 4.9 6.0 34.8 2.9 2.3 2.2 2.4 0.7 2.0 6.7 2.4 1.6 13.0 6.4 3.4 1.6 1.0 8.6 14.2 3.5 2.1 13.3 7.9 2.2 2.3 49.2 1.6 1.4 29.2 6.8 4.8 1.8 132.7 43.4 131.6 126.6 3.3 9.3 170.6 60.6 17.8 66.1 71.3 113.4 107.2 229.4 103.2 21.4 31.5 72.4 90.9 42.1 72.2 162.9 112.1 147.5 49.1 67.2 1.4 176.6 95.6 3.0 0.9 35.2 16.0 12.8 54.9 92.0 87.1 86.3 46.6 109.7 322.8 347.5 99.0 54.1 60.0 152.6 259.4 93.1 36.6 59.6 151.4 80.3 98.4 41.7 36.6 45.2 76.2 202.0 46.9 48.7 132.0 36.6 131.3 56.8 46.4 197.3 25.0 247.1 73.8 1.4 14.4 4.8 2.1 5.6 1.6 4.2 4.3 2.8 15.3 2.9 3.1 2.8 9.3 2.4 1.5 4.6 12.4 6.4 1.9 1.8 9.8 2.1 1.6 3.3 2.9 2.3 2.4 2.1 2.3 1.8 3.4 0.0 4.3 0.3 20.1 5.0 1.9 2.0 8.0 6.4 4.3 5.1 1.6 4.3 3.3 0.0 8.4 39.4 56.0 7.7 1.9 1.8 92.5 3.9 4.8 8.8 6.1 67.3 6.8 0.8 68.2 8.1 11.7 7.6 93.6 23.9 3.6 3.1 21.8 5.0 9.1 19.3 0.0 13.1 17.9 72.1 2.1 27.9 1.8 1.9 59.5 3.8 13.4 5.5 1.1 1.1 8.4 0.4 50.6 1.1 3.8 2.1 1.9 17.5 0.0 2.5 7.3 3.4 8.9 27.3 5.4 4.7 34.2 3.0 35.8 1.4 LMX1B NPS1 ENSG00000136944 "LIM homeobox transcription factor 1 beta" O60663 9 126613928-126701032 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.2;salivary gland: 18.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.3;Breast myoepithelial cells: 7.2;Cardiomyocytes: 1.9;Early spermatids: 1.6;Spermatogonia: 2.1" "Cancer enriched" "Detected in some" 14 "breast cancer: 12.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.5;HEK 293: 3.6;MCF7: 11.9;OE19: 10.4;T-47d: 8.1" "Region enhanced" "Detected in some" "pons and medulla: 2.3" "Region enhanced" "Detected in many" "midbrain: 5.0" "HPA073716, HPA075656" Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA073716: AB_2686630, HPA075656: " "unprognostic (4.17e-1)" "unprognostic (4.72e-2)" "unprognostic (2.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.73e-1)" "unprognostic (1.50e-4)" "unprognostic (1.86e-1)" "unprognostic (2.20e-2)" "unprognostic (3.41e-1)" "unprognostic (2.26e-1)" "unprognostic (1.34e-2)" "unprognostic (3.51e-3)" "unprognostic (1.63e-5)" "unprognostic (1.69e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-6)" "unprognostic (1.13e-2)" 0.6 0.0 0.1 0.0 0.1 0.1 4.1 0.1 5.6 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.0 1.0 3.6 0.0 0.1 0.0 3.8 9.2 0.0 0.2 1.1 0.2 0.0 3.3 0.0 0.0 0.0 18.5 0.0 0.1 2.1 0.1 0.0 6.8 0.0 0.1 1.4 2.6 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.2 0.6 0.3 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.3 0.0 2.5 0.6 3.5 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.5 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 10.4 0.0 0.0 2.4 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.2 0.1 8.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 5.6 1.0 1.0 3.8 9.2 3.3 6.8 2.6 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 8.3 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 1.6 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 LORICRIN LOR ENSG00000203782 "Loricrin cornified envelope precursor protein" P23490 1 153259687-153262124 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Keratinization "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "skin 1: 1842.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "melanoma: 45.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 92 "HDLM-2: 35.2" "HPA076123, HPA077266" Enhanced NA NA 1800000 "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA076123: AB_2732302, HPA077266: AB_2732338" "unprognostic (1.97e-2)" "unprognostic (1.93e-2)" "unprognostic (4.16e-2)" "prognostic favorable (8.53e-4)" "unprognostic (1.65e-1)" "unprognostic (2.69e-1)" "unprognostic (1.61e-1)" "unprognostic (3.41e-1)" "unprognostic (1.47e-1)" "unprognostic (3.03e-1)" "unprognostic (1.02e-2)" 1.1 0.2 0.5 0.2 0.4 0.0 24.2 0.2 0.4 0.8 0.0 0.5 0.0 0.2 0.0 0.7 0.0 0.0 0.7 0.4 0.9 0.2 0.8 0.4 0.1 0.7 0.5 0.5 0.6 0.0 0.2 0.0 0.5 0.2 0.0 0.0 1.7 0.0 10.9 1842.9 0.4 0.0 0.5 0.4 0.3 0.5 1.0 0.6 0.3 0.0 1.8 0.1 21.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.2 0.4 0.4 0.9 0.7 0.5 0.5 0.5 1.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 27.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 67.1;Club cells: 38.4;Early spermatids: 41.9;Endometrial stromal cells: 34.0;Extravillous trophoblasts: 44.2;Fibroblasts: 79.1;Peritubular cells: 39.1;Smooth muscle cells: 32.7" "Cancer enhanced" "Detected in all" "renal cancer: 39.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 777.3;fHDF/TERT166: 1790.7;HSkMC: 356.3;U-138 MG: 475.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043930 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 550000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043930: AB_2678736" "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavorable (3.32e-4)" 27.9 2.4 0.4 6.8 0.4 0.2 17.6 0.5 0.9 10.8 0.8 4.2 3.8 6.2 1.7 5.6 8.9 18.8 23.9 0.3 0.4 4.5 2.1 13.6 3.3 1.3 1.4 5.4 3.3 0.9 1.2 8.1 0.8 4.1 4.5 1.1 3.2 2.6 1.9 12.4 3.7 10.0 1.2 2.6 4.4 1.4 0.5 0.9 6.9 2.1 1.4 14.1 4.8 1.0 0.8 0.2 2.0 0.9 168.7 185.2 0.1 777.3 205.3 73.2 246.4 0.5 0.3 0.1 16.5 1790.7 3.7 0.2 4.5 3.5 196.4 0.1 2.0 0.0 16.3 9.3 203.4 0.4 0.1 356.3 4.4 137.6 7.4 329.3 95.3 0.1 0.0 0.1 83.6 0.0 0.1 0.3 6.4 0.1 1.9 0.1 7.4 0.9 4.9 0.5 0.5 4.2 72.1 0.1 12.9 29.8 0.6 0.6 6.8 475.5 23.2 272.8 9.3 0.0 0.1 0.2 207.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.3 0.4 1.3 1.4 0.8 1.2 0.5 1.0 20.0 9.6 1.1 0.0 0.2 7.8 1.9 67.1 0.0 0.6 1.3 1.1 2.1 0.0 38.4 0.0 0.0 0.8 0.1 0.0 0.0 7.2 41.9 8.4 34.0 9.4 0.0 0.0 0.3 0.6 44.2 79.1 0.0 6.6 0.0 0.1 10.8 0.5 2.2 1.7 2.0 0.0 2.0 0.8 21.6 5.0 14.0 1.3 5.4 1.9 0.6 0.0 0.0 0.0 0.0 1.3 0.0 39.1 0.3 2.8 0.0 0.1 8.3 1.7 19.7 1.1 32.7 0.8 0.6 1.8 10.7 4.8 1.1 0.4 0.1 0.9 LPAR5 "GPR92, GPR93, KPG_010, LPA5" ENSG00000184574 "Lysophosphatidic acid receptor 5" Q9H1C0 12 6618835-6635960 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.9" "Cell type enhanced" "Detected in many" "B-cells: 26.5;Hofbauer cells: 38.0;Microglial cells: 33.7;Proximal enterocytes: 18.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 18.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 83.8;T-cells: 66.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 10.5;HEL: 19.6;HMC-1: 26.0;K-562: 14.8;OE19: 9.4;U-698: 13.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA013170 Approved NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "HPA013170: AB_1849314" "unprognostic (1.94e-1)" "unprognostic (6.43e-2)" "unprognostic (1.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (1.37e-1)" "unprognostic (5.95e-2)" "unprognostic (3.45e-1)" "unprognostic (1.41e-2)" "unprognostic (3.62e-3)" "unprognostic (2.07e-1)" "unprognostic (6.27e-2)" "unprognostic (7.99e-3)" "unprognostic (5.43e-1)" "prognostic favorable (6.56e-5)" "unprognostic (7.43e-2)" 1.9 2.5 6.0 5.3 6.1 1.0 1.3 6.1 5.9 5.8 3.4 8.9 9.7 0.5 2.7 20.9 1.6 1.7 4.1 5.4 6.8 0.7 1.3 1.9 8.9 10.3 8.9 0.7 0.5 0.8 1.0 5.4 9.4 1.0 8.3 0.2 5.5 1.3 0.2 6.9 8.9 1.0 10.2 9.3 7.2 1.6 11.8 2.6 1.6 0.1 12.4 2.1 9.6 14.4 5.8 0.7 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.3 10.5 4.3 1.3 0.0 0.1 7.0 0.0 3.2 0.0 0.0 0.0 19.6 0.6 0.4 0.0 0.0 26.0 0.0 3.5 0.1 1.5 0.0 0.0 4.0 14.8 0.0 0.0 0.5 0.6 6.1 0.1 9.4 1.0 4.8 0.0 0.0 0.0 3.3 0.1 0.1 3.0 0.0 0.0 1.1 0.0 2.2 0.1 0.0 3.9 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.0 10.4 0.3 0.1 66.8 3.4 51.2 83.8 11.2 40.2 17.3 82.7 10.8 24.6 0.8 4.6 6.1 1.1 18.0 20.1 6.0 6.1 6.1 5.9 5.4 6.8 10.3 8.9 9.4 10.2 11.8 14.4 0.2 0.0 0.0 0.0 26.5 1.5 0.4 3.9 1.8 0.0 0.6 0.5 2.8 1.5 4.4 1.8 0.0 0.3 2.8 16.9 0.0 0.3 4.9 0.4 0.1 1.5 1.2 0.8 0.2 0.9 0.2 0.6 3.6 0.7 16.5 0.0 1.1 0.2 38.0 0.0 0.3 11.1 2.0 15.6 7.0 14.5 0.0 13.9 0.0 33.7 4.6 0.1 17.5 0.5 0.1 9.4 16.8 0.0 2.7 0.7 18.4 0.1 0.6 0.1 0.0 0.1 0.2 0.6 1.4 10.3 1.3 0.5 6.9 0.0 13.0 2.2 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 LPO SPO ENSG00000167419 Lactoperoxidase P22079 17 58218548-58268518 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Antimicrobial, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 404 "salivary gland: 1026.8" "Group enriched" "Detected in some" 6 "Breast glandular cells: 25.2;Early spermatids: 8.3;Late spermatids: 14.1" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "midbrain: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "THP-1: 9.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028688 Enhanced Supported "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 43: THP-1 - Innate immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA028688: AB_10601909" "unprognostic (2.74e-1)" "unprognostic (5.12e-2)" "unprognostic (4.14e-3)" "unprognostic (1.56e-3)" "unprognostic (2.41e-2)" "unprognostic (9.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (2.40e-2)" "unprognostic (6.27e-3)" "unprognostic (6.32e-2)" "unprognostic (2.56e-1)" "unprognostic (0.00e+0)" "unprognostic (3.41e-2)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (1.22e-1)" 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.5 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1026.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 2.5 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.7 25.2 0.5 0.7 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 8.3 0.3 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 1.3 0.0 0.4 0.0 0.2 1.7 0.3 0.0 0.0 0.0 0.0 14.1 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.5 1.4 0.1 0.0 0.3 0.0 0.2 0.1 2.6 0.4 0.0 0.3 0.0 0.2 0.0 0.5 0.5 LPP ENSG00000145012 "LIM domain containing preferred translocation partner in lipoma" Q93052 3 188153284-188890671 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 566.5;Late spermatids: 1737.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 97.0;EFO-21: 115.2;U-698: 200.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011133, HPA017342" Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 2700000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Focal adhesion sites, Cytosol" "HPA011133: AB_1853247, HPA017342: AB_1853249" "unprognostic (1.50e-1)" "unprognostic (4.97e-3)" "unprognostic (1.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.86e-1)" "unprognostic (4.05e-1)" "unprognostic (2.43e-3)" "unprognostic (7.97e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (3.44e-3)" "unprognostic (2.10e-1)" "unprognostic (2.57e-3)" "unprognostic (2.25e-2)" "unprognostic (6.86e-2)" "unprognostic (2.82e-3)" "unprognostic (1.48e-1)" 29.3 10.8 6.7 28.4 8.9 9.9 18.8 9.1 9.7 27.5 27.3 73.3 13.8 61.9 11.8 49.4 32.2 21.3 16.7 6.1 11.2 11.5 12.1 19.1 17.2 15.6 7.9 14.7 8.8 9.9 2.9 11.5 12.6 39.0 31.7 2.4 12.0 53.1 12.4 12.0 23.0 81.3 6.6 10.8 32.7 18.6 13.8 8.0 8.8 9.1 21.4 57.0 22.1 7.8 25.6 23.3 16.7 11.3 35.3 36.0 17.9 16.0 20.9 11.8 7.8 42.2 12.1 97.0 115.2 37.3 14.7 10.7 5.2 11.0 29.5 10.7 5.7 4.6 18.4 11.1 15.0 2.0 5.5 25.7 15.3 26.4 22.5 16.9 20.1 5.2 0.2 2.0 21.0 8.1 5.1 2.1 6.6 16.3 7.6 6.2 12.3 0.5 13.1 26.8 1.1 0.3 35.3 11.4 19.2 27.3 9.0 8.8 43.7 27.1 20.8 19.6 41.1 0.2 4.0 200.0 13.6 4.3 24.9 0.8 4.9 2.2 5.1 4.5 3.3 3.3 4.5 3.8 2.6 5.6 2.4 2.9 18.9 4.8 4.6 5.3 1.8 1.9 6.7 8.9 9.1 9.7 6.1 11.2 15.6 7.9 12.6 6.6 13.8 7.8 104.7 89.8 69.8 357.5 48.5 78.0 84.9 65.0 70.0 9.5 141.8 111.5 143.0 100.1 86.2 69.9 14.6 44.7 65.7 207.1 29.4 139.7 566.5 49.3 134.4 91.8 77.5 12.0 132.8 90.9 24.1 124.9 97.9 93.6 18.3 136.6 126.4 94.8 42.5 5.0 191.2 91.7 44.7 65.1 121.0 1737.1 225.3 75.8 80.0 308.2 55.8 24.8 54.6 395.6 214.9 120.2 158.1 476.9 24.6 172.5 127.5 80.2 60.9 7.1 335.2 159.2 368.2 9.8 8.0 64.2 68.2 18.6 55.3 46.8 151.3 149.3 LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753120 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 104.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 11 "NTERA-2: 15.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA070726 Uncertain "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "Endoplasmic reticulum" "HPA070726: " "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (4.75e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.65e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-4)" "unprognostic (4.49e-6)" "unprognostic (6.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" 0.2 0.2 0.6 0.2 0.7 0.5 0.4 0.7 2.6 0.2 1.6 0.5 1.2 0.1 0.3 0.0 0.2 0.5 0.1 0.7 1.2 0.1 2.1 0.3 0.1 1.0 1.1 0.3 0.8 0.2 0.2 0.1 1.3 0.4 0.1 1.0 0.1 0.5 0.8 0.4 1.6 0.1 0.7 0.1 0.3 0.8 0.7 0.0 1.5 0.0 0.1 0.1 0.1 0.9 0.5 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.3 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 15.3 0.0 0.0 0.0 0.0 0.1 1.4 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.6 1.9 0.1 0.1 0.6 0.1 0.1 0.1 0.1 1.5 0.2 0.1 0.1 0.8 0.2 0.2 0.2 0.1 2.2 0.6 0.7 0.7 2.6 0.7 1.2 1.0 1.1 1.3 0.7 0.7 0.9 0.2 0.0 4.4 4.6 0.1 1.1 4.4 4.0 0.6 0.5 8.6 9.1 0.3 11.5 1.7 0.0 0.0 0.1 0.3 0.8 3.9 1.2 15.2 0.9 0.5 0.3 0.0 0.0 2.2 0.8 0.1 1.5 2.0 2.2 0.0 104.4 1.4 2.2 0.1 0.0 0.6 0.9 2.0 0.8 2.8 3.2 0.0 0.3 5.4 0.0 0.0 3.9 0.0 1.0 2.2 1.2 0.0 0.0 0.0 2.4 12.3 1.0 0.9 0.8 0.0 1.4 8.1 10.5 4.7 1.4 1.1 0.3 0.6 0.0 1.2 0.6 LRATD1 "FAM84A, FLJ35392, NSE1" ENSG00000162981 "LRAT domain containing 1" Q96KN4 2 14632700-14650814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 32.2;intestine: 41.0" "Group enriched" "Detected in some" 8 "Cytotrophoblasts: 162.2;Syncytiotrophoblasts: 207.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 35.0" "Group enriched" "Detected in many" 7 "amygdala: 19.7;basal ganglia: 10.8;cerebral cortex: 18.1;hippocampal formation: 13.0;white matter: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 9.4;hTCEpi: 18.0;RT4: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047703 Uncertain Approved Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA047703: AB_2680123" "unprognostic (1.05e-2)" "unprognostic (9.22e-2)" "unprognostic (2.24e-3)" "unprognostic (1.13e-1)" "unprognostic (4.28e-2)" "unprognostic (7.38e-2)" "unprognostic (2.62e-2)" "unprognostic (1.23e-1)" "unprognostic (1.48e-1)" "unprognostic (4.44e-2)" "unprognostic (1.20e-1)" "unprognostic (9.27e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-1)" "unprognostic (1.58e-1)" "unprognostic (5.57e-3)" "unprognostic (1.36e-1)" 0.5 1.4 19.7 4.9 10.8 0.0 2.4 0.0 18.1 10.6 0.0 41.0 26.3 2.7 32.2 28.6 2.9 3.4 2.1 13.0 2.0 4.0 1.4 3.0 0.2 0.0 0.2 8.2 3.2 5.2 3.3 5.3 0.0 13.6 36.2 0.9 13.9 2.0 0.9 18.5 25.3 2.8 0.0 0.2 3.0 12.3 1.4 1.3 2.2 0.1 1.4 14.8 16.6 6.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 2.5 0.6 0.5 0.0 0.3 0.0 0.0 0.3 0.0 9.4 1.0 4.2 1.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 18.0 0.0 5.9 0.2 0.0 0.0 0.0 0.0 1.3 7.8 0.0 0.2 0.8 0.0 4.0 0.0 0.0 0.1 6.9 49.3 4.3 2.0 0.0 1.8 0.0 0.3 0.0 0.0 2.9 8.2 0.7 0.0 3.2 0.0 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 10.8 0.0 18.1 13.0 2.0 0.0 0.2 0.0 0.0 1.4 6.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 162.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 22.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 207.8 0.0 0.0 0.0 0.0 LRBA "BGL, CDC4L, LAB300, LBA" ENSG00000198589 "LPS responsive beige-like anchor protein" P50851 4 150264435-151015727 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 213.7;Inhibitory neurons: 192.6;Microglial cells: 161.1;Oligodendrocyte precursor cells: 239.8;Oligodendrocytes: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019366, HPA023597" Approved Approved "Golgi apparatus,Cytosol" NA NA 340000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus" Cytosol "HPA019366: AB_2138441, HPA023597: AB_1853256" "unprognostic (2.60e-1)" "unprognostic (4.70e-2)" "unprognostic (1.64e-3)" "unprognostic (4.49e-3)" "unprognostic (4.38e-1)" "unprognostic (8.65e-2)" "unprognostic (5.88e-2)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (6.92e-2)" "unprognostic (2.29e-2)" "unprognostic (5.88e-2)" "prognostic favorable (2.22e-16)" "unprognostic (7.15e-2)" "unprognostic (2.36e-1)" "unprognostic (4.79e-1)" "unprognostic (3.00e-1)" 7.3 10.7 3.4 9.3 6.9 11.1 22.7 11.1 3.8 13.1 18.6 16.7 13.3 6.9 14.2 13.9 15.2 9.9 8.3 2.9 2.2 23.5 13.4 11.0 15.8 5.1 4.5 8.9 13.5 34.2 6.5 7.0 6.1 20.0 17.4 14.9 13.8 8.9 7.2 19.3 11.5 6.6 3.4 9.6 17.0 9.4 3.7 18.7 19.1 8.9 17.7 12.3 7.0 6.3 27.6 14.3 11.9 11.1 12.2 18.5 17.0 6.0 15.8 10.9 10.2 30.9 35.6 33.7 7.2 8.6 7.5 13.7 22.1 36.6 15.3 25.9 15.8 20.8 19.8 19.0 7.5 29.0 16.2 14.6 21.1 16.0 24.6 23.9 32.9 14.8 22.4 24.3 12.9 21.9 21.9 7.7 10.7 23.7 10.3 18.4 12.0 12.6 42.0 33.7 39.3 13.0 15.1 32.1 7.4 18.1 32.4 6.1 17.2 16.8 12.2 8.7 11.4 20.9 20.5 20.5 26.2 16.0 6.6 5.7 0.6 1.2 5.0 0.2 3.3 4.9 3.3 4.7 1.0 2.1 2.3 4.0 0.1 3.2 2.1 2.1 4.6 1.8 3.4 6.9 11.1 3.8 2.9 2.2 5.1 4.5 6.1 3.4 3.7 6.3 10.4 16.0 14.9 148.5 42.5 17.5 16.4 21.0 28.5 33.5 30.8 18.2 55.9 21.5 21.5 51.5 148.0 23.7 37.7 19.7 9.8 15.2 25.5 51.2 11.0 13.3 42.0 40.2 213.7 13.5 10.6 12.8 56.6 61.8 6.3 22.4 10.0 20.5 6.1 30.3 192.6 23.8 24.4 11.1 12.8 5.5 9.6 17.7 16.0 161.1 8.2 17.7 46.4 239.8 217.4 17.2 20.2 10.1 38.3 22.4 22.0 15.8 36.7 72.6 6.6 13.7 9.8 16.6 22.3 37.3 23.7 24.2 45.6 25.9 27.2 24.0 LRCH2 KIAA1495 ENSG00000130224 "Leucine rich repeats and calponin homology domain containing 2" Q5VUJ6 X 115110616-115234096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 23.8;Excitatory neurons: 24.4;Inhibitory neurons: 38.0;Oligodendrocyte precursor cells: 48.2;Oligodendrocytes: 32.0;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 21.4;U-266/70: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003233, HPA076892" Approved Approved "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003233: AB_2265929, HPA076892: " "unprognostic (9.74e-2)" "unprognostic (9.48e-2)" "unprognostic (1.14e-2)" "unprognostic (4.22e-5)" "unprognostic (2.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (9.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (1.01e-2)" "unprognostic (1.84e-1)" "unprognostic (4.29e-5)" "unprognostic (1.09e-3)" "unprognostic (1.34e-1)" "unprognostic (7.75e-2)" "unprognostic (1.16e-2)" 2.7 4.4 3.9 1.4 4.1 0.0 2.0 4.2 4.7 5.2 0.6 8.2 0.5 5.1 2.1 1.6 3.4 2.6 2.6 4.0 6.8 1.1 0.2 2.8 0.7 3.3 3.8 7.0 0.5 0.3 4.4 7.5 3.5 8.3 1.9 3.6 0.5 7.3 0.5 0.5 2.0 5.1 3.9 1.8 2.0 2.1 6.2 0.5 2.3 1.5 0.2 4.9 3.3 4.3 0.0 0.0 6.4 4.7 6.4 5.3 0.0 4.3 9.2 4.1 9.3 0.0 0.0 0.1 0.1 5.7 3.2 0.3 21.4 0.0 6.2 0.0 5.8 0.0 0.0 0.0 5.1 0.0 0.1 3.1 0.0 1.6 0.3 10.8 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 6.2 0.0 4.6 0.0 5.1 0.6 0.0 8.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 2.5 0.1 6.0 14.0 2.5 0.0 1.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.1 4.2 4.7 4.0 6.8 3.3 3.8 3.5 3.9 6.2 4.3 9.3 3.2 12.3 23.8 0.0 0.6 0.1 0.0 0.6 6.9 0.1 0.3 7.5 0.0 0.0 1.8 0.0 0.1 0.0 0.0 1.9 0.0 9.1 0.1 5.9 6.7 0.0 0.0 24.4 0.0 0.2 6.3 0.0 0.1 0.0 8.4 2.9 0.0 0.6 1.7 38.0 0.0 0.0 0.0 1.0 2.9 8.7 0.1 1.8 9.4 0.0 6.4 0.0 48.2 32.0 0.0 0.0 6.4 0.0 1.2 0.0 0.0 0.0 2.5 26.3 3.6 7.8 5.4 2.9 0.0 0.1 0.3 0.2 5.7 0.0 0.1 LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;cervix: 10.1;parathyroid gland: 11.1" "Group enriched" "Detected in some" 19 "Excitatory neurons: 873.9;Inhibitory neurons: 581.5;Oligodendrocyte precursor cells: 296.1" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 16.4;HSkMC: 3.1;RPTEC TERT1: 5.2;SCLC-21H: 8.8;U-138 MG: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" 1.4 2.2 5.3 1.0 7.5 0.0 1.4 0.0 16.5 10.1 0.0 2.0 0.2 2.5 0.6 0.5 3.3 1.0 0.6 7.9 5.9 0.2 0.3 0.7 0.0 0.8 1.4 1.6 0.3 11.1 0.8 1.1 4.9 2.4 1.0 2.6 0.3 6.4 0.2 0.6 0.4 1.5 0.8 0.6 0.7 0.9 2.0 0.3 0.5 0.5 0.2 6.1 5.2 4.3 0.0 0.0 1.7 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 8.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.5 0.0 16.5 7.9 5.9 0.8 1.4 4.9 0.8 2.0 4.3 0.5 0.0 0.0 29.7 0.0 0.3 0.0 0.0 0.0 8.2 0.1 0.6 1.0 2.8 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.2 0.3 7.8 0.9 0.0 0.0 873.9 0.0 0.1 7.9 0.0 0.6 0.0 0.2 0.0 0.5 0.1 0.0 581.5 0.0 0.0 0.0 0.8 1.7 8.4 0.1 1.8 24.4 0.0 0.4 0.0 296.1 11.8 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.4 1.5 0.0 2.1 0.0 0.3 0.1 0.2 2.1 0.0 0.1 LRIT2 "AC022389.4, LRRC22" ENSG00000204033 "Leucine rich repeat, Ig-like and transmembrane domains 2" A6NDA9 10 84220571-84225544 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "retina: 59.0" "Group enriched" "Detected in some" 4 "Bipolar cells: 7.5;Cone photoreceptor cells: 8.4;Rod photoreceptor cells: 24.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA037788 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA037788: AB_10672393" "unprognostic (3.12e-1)" "unprognostic (1.09e-3)" "unprognostic (3.99e-1)" "unprognostic (9.44e-2)" "unprognostic (2.36e-1)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.5 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 59.0 0.0 0.0 0.0 3.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.3 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LRP4 "CLSS, LRP-4, MEGF7, SOST2" ENSG00000134569 "LDL receptor related protein 4" O75096 11 46856717-46918642 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.7;skin 1: 31.6" "Cell type enhanced" "Detected in many" "Astrocytes: 123.1;Cone photoreceptor cells: 41.7;Distal enterocytes: 31.1;Oligodendrocyte precursor cells: 137.2;Oligodendrocytes: 31.3" "Group enriched" "Detected in all" 4 "colorectal cancer: 12.2;endometrial cancer: 8.6;glioma: 13.2;testis cancer: 15.6;thyroid cancer: 28.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 21.3;SuSa: 16.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011934, HPA012300" Approved Uncertain Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli, Mitochondria" "HPA011934: AB_1853286, HPA012300: AB_1853288" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.86e-1)" "unprognostic (1.33e-2)" "unprognostic (4.39e-2)" "unprognostic (9.73e-3)" "unprognostic (5.29e-4)" "unprognostic (8.61e-2)" "unprognostic (2.29e-2)" "unprognostic (2.77e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (7.59e-2)" "unprognostic (7.95e-2)" "unprognostic (2.76e-2)" "unprognostic (9.90e-3)" "unprognostic (6.79e-2)" 0.7 1.4 23.3 0.9 30.5 0.0 1.5 19.1 21.3 2.3 0.0 4.8 3.4 1.6 0.9 1.8 1.4 2.0 6.9 24.2 16.0 0.7 0.2 2.9 0.1 46.7 23.0 4.6 2.2 5.6 2.6 2.6 19.8 2.1 3.4 7.9 1.7 2.3 4.4 31.6 4.9 1.5 21.3 3.9 7.8 1.1 30.9 1.5 2.4 7.7 0.3 0.9 1.4 25.6 0.1 9.6 21.3 6.5 13.4 3.7 4.9 1.0 1.9 2.8 3.2 2.8 0.0 0.0 1.4 11.4 3.1 3.9 12.0 7.5 2.2 0.0 10.3 1.0 3.8 6.8 2.8 0.1 1.9 4.5 4.2 4.4 1.1 2.5 2.5 2.6 0.9 0.0 1.6 0.8 0.2 0.3 11.9 0.0 0.9 1.6 7.3 0.0 0.3 2.8 0.1 14.2 1.2 0.0 3.4 16.2 0.3 0.5 0.2 5.7 3.5 6.5 2.1 0.0 0.0 0.4 4.3 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 30.5 19.1 21.3 24.2 16.0 46.7 23.0 19.8 21.3 30.9 25.6 0.2 0.0 1.9 123.1 0.0 8.2 2.7 2.4 10.8 0.5 0.3 1.9 6.2 0.0 1.9 1.8 41.7 2.6 0.0 31.1 1.9 0.0 0.5 1.0 4.7 1.0 0.0 0.0 19.7 0.4 0.4 5.0 3.1 4.4 5.1 1.6 1.8 0.4 0.2 0.0 18.6 2.8 0.0 0.0 0.4 0.0 1.8 0.2 1.8 15.0 0.6 9.3 0.0 137.2 31.3 0.3 3.0 1.2 0.0 1.0 8.0 0.3 1.1 2.7 0.0 12.4 0.9 0.2 0.8 2.3 10.9 1.4 0.2 8.4 3.3 0.8 LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 31.3;Granulosa cells: 68.6;Leydig cells: 101.9;Peritubular cells: 31.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cell line enriched" "Detected in many" 5 "LHCN-M2: 1237.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" 8.1 2.4 1.6 1.1 1.7 0.2 12.9 1.6 2.4 22.5 1.7 2.7 1.6 15.7 12.1 6.0 17.3 27.4 13.2 1.7 1.6 2.8 3.5 3.2 2.1 1.6 1.7 76.2 2.3 2.0 2.4 0.6 1.5 5.6 3.3 1.8 2.7 3.2 2.1 3.0 2.3 6.0 1.6 3.3 6.9 5.0 2.3 6.2 3.8 2.8 1.0 4.4 5.8 1.6 0.0 0.0 58.8 0.5 6.0 29.4 0.1 1.6 18.2 0.6 2.8 0.0 0.2 0.0 3.4 1.5 7.3 0.1 0.0 0.0 4.3 0.0 1.4 0.1 0.0 0.1 8.3 0.5 0.2 28.1 0.7 21.5 0.0 141.1 140.9 0.6 0.0 0.1 1237.5 0.0 0.1 0.4 3.1 0.1 0.1 0.1 244.0 0.2 0.2 0.1 1.3 1.3 0.1 0.0 0.1 0.1 0.0 1.7 11.8 0.2 1.5 15.2 2.3 1.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 1.6 2.4 1.7 1.6 1.6 1.7 1.5 1.6 2.3 1.6 3.6 0.0 1.1 4.6 0.2 0.9 0.2 0.9 0.0 3.7 0.7 0.8 1.1 0.0 0.5 1.8 2.1 0.3 0.3 0.0 0.0 1.7 3.5 2.7 15.3 4.4 0.0 0.0 6.9 0.4 0.2 31.3 1.1 4.6 1.3 68.6 6.1 0.5 0.4 0.0 8.7 0.1 2.0 0.0 2.7 2.9 101.9 0.5 5.4 10.3 0.6 0.6 0.0 2.5 5.3 0.2 0.3 31.6 0.0 0.3 0.1 0.3 0.1 2.2 65.7 16.1 17.8 0.6 0.5 0.4 0.6 0.0 0.9 6.6 0.2 0.2 LRRC18 "MGC34773, UNQ933, UNQ9338, VKGE9338" ENSG00000165383 "Leucine rich repeat containing 18" Q8N456 10 48909483-48914232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 12.1;fallopian tube: 7.6;testis: 14.0" "Group enriched" "Detected in some" 8 "Early spermatids: 222.0;Late spermatids: 64.1" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039256, HPA076699" Enhanced Approved Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA039256: AB_10671873, HPA076699: " "unprognostic (1.31e-2)" "unprognostic (3.66e-2)" "unprognostic (9.83e-4)" "unprognostic (3.10e-1)" "unprognostic (4.82e-2)" "unprognostic (1.98e-1)" "unprognostic (2.00e-1)" "unprognostic (8.11e-2)" "unprognostic (1.11e-1)" "unprognostic (3.16e-2)" "unprognostic (8.57e-3)" "unprognostic (4.08e-1)" "unprognostic (1.13e-1)" 0.0 0.0 0.3 0.4 0.2 0.4 0.3 0.5 0.3 0.6 12.1 0.4 0.2 0.2 0.0 0.1 7.6 0.3 0.3 0.8 0.3 0.0 0.0 1.5 0.2 1.0 0.9 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.7 0.0 0.1 0.0 0.0 0.8 0.4 0.2 0.6 0.1 0.2 14.0 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.5 0.3 0.8 0.3 1.0 0.9 0.8 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 222.0 6.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 64.1 1.8 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.2 2.8 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LRRC26 bA350O14.10 ENSG00000184709 "Leucine rich repeat containing 26" Q2I0M4 9 137168758-137170051 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 290.0" "Cell type enriched" "Detected in many" 5 "Intestinal goblet cells: 598.0" "Cancer enriched" "Detected in many" 5 "prostate cancer: 47.6" "Region enriched" "Detected in single" 5 "cerebellum: 2.6" "Immune cell enriched" "Detected in single" 1177 "plasmacytoid DC: 117.6" "Lineage enriched" "Detected in single" 1177 "dendritic cells: 117.6" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 130.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA056312 Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoli fibrillar center" "HPA056312: AB_2683098" "unprognostic (1.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.04e-2)" "prognostic favorable (4.82e-6)" "unprognostic (3.39e-1)" "unprognostic (1.67e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "prognostic favorable (3.48e-4)" "unprognostic (3.27e-1)" "unprognostic (2.29e-1)" 0.1 0.0 0.2 0.3 0.4 0.0 7.3 2.6 0.5 0.4 0.0 11.2 1.7 1.1 0.0 2.8 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.1 53.1 0.5 0.0 290.0 0.5 0.0 5.1 7.2 0.0 0.2 0.1 5.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 5.4 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.9 0.1 0.3 0.7 20.8 0.1 130.9 0.0 0.0 1.0 0.2 0.5 6.0 0.0 0.0 2.7 0.5 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.6 0.0 0.5 0.2 0.4 2.6 0.5 0.1 0.5 0.0 0.1 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.3 1.2 1.0 1.7 0.5 0.0 0.0 101.2 64.4 0.4 4.3 1.0 0.0 0.0 0.1 81.8 15.2 1.9 0.1 0.5 13.0 1.6 1.0 9.0 0.0 0.1 0.4 0.0 0.4 9.2 21.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 598.0 4.1 0.0 0.9 1.1 0.0 1.4 56.9 0.0 0.6 0.0 0.0 0.0 0.1 0.2 11.8 0.0 0.6 28.4 28.8 0.1 0.4 0.0 0.0 0.0 0.4 0.2 2.8 3.5 0.3 0.0 0.6 0.0 24.3 3.7 LRRC36 FLJ11004 ENSG00000159708 "Leucine rich repeat containing 36" Q1X8D7 16 67326798-67385204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 35.3" "Group enriched" "Detected in some" 7 "Alveolar cells type 2: 94.7;Early spermatids: 192.8;Late spermatids: 118.0;Spermatocytes: 68.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "plasmacytoid DC: 9.7" "Lineage enriched" "Detected in many" 7 "dendritic cells: 9.7" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 1.4;JURKAT: 1.3;TIME: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA058479 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 83: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "HPA058479: AB_2683728" "unprognostic (4.59e-2)" "unprognostic (6.84e-2)" "unprognostic (2.17e-2)" "unprognostic (2.26e-5)" "unprognostic (5.27e-2)" "unprognostic (4.32e-2)" "unprognostic (5.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.99e-2)" "unprognostic (1.65e-1)" "unprognostic (3.32e-3)" "unprognostic (4.49e-2)" "unprognostic (1.36e-1)" "unprognostic (1.26e-1)" "unprognostic (3.70e-1)" "unprognostic (1.99e-1)" "unprognostic (3.88e-2)" 0.1 0.0 0.2 0.0 0.3 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 3.0 0.1 0.0 0.1 0.4 0.3 0.0 4.9 0.2 0.4 0.3 0.1 0.3 0.0 0.1 6.1 0.3 0.0 0.5 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 35.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.2 0.3 0.2 0.2 0.1 0.4 0.4 0.3 0.3 0.1 0.2 0.0 0.4 3.2 94.7 0.0 0.3 0.3 0.4 0.2 0.0 0.8 0.3 0.3 0.7 0.0 0.8 0.0 0.0 0.1 6.7 0.5 0.0 1.9 192.8 15.4 0.2 3.2 2.4 0.0 1.2 0.0 0.1 1.4 0.0 0.4 8.8 1.5 0.0 0.0 0.2 0.0 2.6 0.6 0.0 0.0 0.7 118.0 2.1 0.7 7.2 1.9 0.7 1.5 0.0 2.0 0.4 0.1 0.3 1.5 0.0 0.1 0.5 1.3 12.0 0.2 0.0 0.7 0.4 68.2 15.1 0.0 0.3 0.3 0.3 0.6 1.7 0.3 LRRC37B ENSG00000185158 "Leucine rich repeat containing 37B" Q96QE4 17 32007872-32053504 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1" "Cell type enhanced" "Detected in many" "Early spermatids: 101.9;Excitatory neurons: 45.4;Spermatocytes: 66.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Group enriched" "Detected in many" 4 "granulocytes: 1.5;NK-cells: 3.8;T-cells: 2.6" "Low cell line specificity" "Detected in all" HPA015135 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA015135: AB_1853309" "unprognostic (5.46e-3)" "unprognostic (2.56e-2)" "unprognostic (5.08e-2)" "unprognostic (5.30e-2)" "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (3.60e-2)" "unprognostic (9.65e-3)" "unprognostic (5.06e-2)" "unprognostic (3.19e-2)" "unprognostic (1.72e-4)" "unprognostic (6.99e-2)" "unprognostic (5.72e-3)" "unprognostic (6.94e-2)" "unprognostic (3.35e-2)" "unprognostic (4.97e-2)" "unprognostic (1.36e-3)" 4.7 3.7 7.5 3.7 6.6 25.1 5.2 13.7 10.3 6.9 0.9 4.9 3.4 6.2 4.7 4.2 6.8 3.6 2.6 8.0 4.2 3.6 2.1 5.6 4.6 4.8 3.4 9.1 3.2 5.7 8.3 3.5 5.2 4.7 4.6 6.9 4.7 2.8 3.5 10.5 5.0 5.2 2.2 6.2 5.0 17.9 5.1 10.9 4.1 1.4 4.5 4.6 5.9 7.1 2.7 5.0 15.6 8.9 3.9 4.7 4.8 2.4 9.0 6.9 8.7 6.8 2.6 7.1 5.0 5.5 8.5 3.6 9.3 1.9 5.4 2.2 7.6 3.4 8.1 2.6 5.8 13.3 5.8 5.1 5.9 6.3 15.9 6.6 5.9 12.1 8.2 6.8 2.6 2.5 23.4 20.5 4.8 2.5 3.3 16.2 3.7 5.9 3.9 6.6 2.9 5.0 6.1 3.8 8.8 5.2 10.4 20.9 5.0 4.8 3.2 10.8 6.1 6.8 10.4 7.5 3.4 13.2 3.4 0.0 0.2 1.5 0.5 0.2 1.0 0.1 1.0 1.4 0.4 0.4 1.4 0.4 0.5 3.8 0.1 0.6 2.6 0.3 7.5 6.6 13.7 10.3 8.0 4.2 4.8 3.4 5.2 2.2 5.1 7.1 7.4 6.4 9.1 39.2 5.1 4.1 6.9 3.8 2.8 10.0 7.3 5.6 4.7 7.2 7.1 1.8 0.0 2.3 10.0 2.9 9.8 8.9 101.9 7.9 6.3 6.0 1.8 7.4 45.4 10.5 2.3 6.0 1.5 4.7 3.8 7.0 8.2 2.9 9.7 3.3 33.4 5.7 4.1 8.7 6.9 22.9 6.8 7.9 8.8 14.0 9.3 14.5 20.6 39.7 28.3 9.2 1.8 7.2 3.8 9.1 6.8 8.3 7.8 9.7 0.0 8.9 7.8 66.7 13.0 1.6 5.1 2.2 9.0 4.6 4.8 7.7 LRRC61 "FLJ31392, HSPC295, MGC3036" ENSG00000127399 "Leucine rich repeat containing 61" Q9BV99 7 150323263-150338156 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 80.6;Hep G2: 53.3;NTERA-2: 67.0" "Low region specificity" "Detected in all" HPA019355 Approved Approved Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA019355: AB_1853339" "unprognostic (4.05e-2)" "unprognostic (9.50e-2)" "unprognostic (1.61e-3)" "unprognostic (5.91e-3)" "prognostic unfavorable (1.11e-5)" "unprognostic (1.46e-2)" "unprognostic (4.43e-3)" "unprognostic (1.82e-1)" "unprognostic (1.76e-2)" "unprognostic (4.22e-2)" "unprognostic (2.53e-2)" "unprognostic (1.56e-1)" "unprognostic (1.66e-2)" "prognostic favorable (2.85e-4)" "unprognostic (1.21e-1)" "unprognostic (3.27e-1)" "unprognostic (1.69e-3)" 4.0 18.3 9.5 4.5 8.4 1.6 4.5 6.9 8.7 7.5 9.8 5.7 4.3 6.5 2.0 8.8 14.5 4.0 4.1 7.7 13.1 12.1 23.4 4.4 7.3 9.7 10.1 15.2 11.2 11.4 13.5 3.8 10.4 6.6 1.9 2.8 5.3 4.3 2.2 6.8 5.8 2.0 8.2 6.1 6.1 9.1 13.4 11.5 8.7 2.3 3.9 4.7 6.5 6.7 20.0 0.5 0.6 0.1 0.0 0.0 9.0 0.2 0.0 2.4 7.8 37.9 19.4 6.2 8.2 0.3 0.0 17.6 0.0 0.0 1.3 80.6 24.4 7.4 23.5 53.3 13.8 0.0 3.7 1.6 7.9 0.0 0.0 0.6 0.1 40.2 25.9 11.5 0.0 36.5 37.5 3.2 67.0 13.8 0.0 0.0 0.1 16.5 5.7 13.2 34.6 33.4 33.6 7.2 13.7 5.6 5.6 4.5 0.1 0.0 0.1 0.0 0.1 12.5 4.4 0.0 0.0 0.0 0.0 2.8 2.9 8.5 10.8 1.1 8.3 8.7 7.3 8.2 3.0 10.7 7.0 8.4 13.1 8.7 1.3 17.9 12.7 5.7 9.5 8.4 6.9 8.7 7.7 13.1 9.7 10.1 10.4 8.2 13.4 6.7 0.3 6.4 1.5 2.3 7.1 1.1 4.7 16.5 8.6 7.8 8.0 8.9 2.2 11.5 6.8 16.5 0.0 25.2 11.1 9.4 19.6 27.3 5.7 20.9 1.6 1.7 19.3 3.8 1.7 28.4 24.5 4.7 7.1 5.8 1.3 22.9 1.8 22.6 6.0 13.5 3.6 6.7 18.3 1.3 0.0 16.3 10.2 3.3 3.6 0.0 16.5 13.7 11.3 4.5 0.3 27.9 11.2 5.7 3.5 4.0 11.7 48.7 20.1 4.5 0.0 5.3 3.2 20.8 23.7 8.1 2.7 27.0 7.4 9.0 10.6 3.0 LRRFIP2 HUFI-2 ENSG00000093167 "LRR binding FLII interacting protein 2" Q9Y608 3 37052626-37183689 "Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 516.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035956, HPA042023" Uncertain Approved "Plasma membrane,Actin filaments" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA035956: AB_10671238, HPA042023: AB_2677802" "unprognostic (2.03e-3)" "prognostic favorable (6.31e-4)" "unprognostic (1.16e-2)" "unprognostic (7.90e-2)" "unprognostic (2.48e-1)" "unprognostic (2.97e-1)" "unprognostic (5.41e-2)" "unprognostic (1.82e-1)" "unprognostic (3.09e-2)" "unprognostic (2.56e-2)" "unprognostic (4.99e-3)" "unprognostic (1.98e-1)" "unprognostic (4.13e-3)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (4.84e-3)" "unprognostic (3.76e-2)" 23.4 24.0 43.7 20.1 46.9 44.3 22.3 43.6 49.0 46.0 33.6 38.3 35.4 31.8 19.7 52.6 25.8 22.0 75.8 38.8 44.4 24.0 48.5 27.0 18.1 43.4 42.0 27.4 19.2 33.3 18.6 20.8 44.8 41.0 34.2 36.0 28.5 24.3 97.9 37.0 36.2 31.5 41.0 45.0 26.5 71.8 46.4 18.8 27.5 45.3 23.2 24.2 40.9 60.9 56.6 30.8 34.9 27.7 45.5 69.3 30.5 149.9 148.2 82.6 94.3 29.0 25.3 22.2 24.0 145.4 40.8 28.8 25.8 74.2 134.3 49.7 20.2 39.8 44.0 28.6 64.8 31.9 23.3 31.1 52.1 107.8 110.4 45.8 58.2 34.0 32.3 37.8 69.5 14.4 27.2 17.0 23.0 23.0 39.2 13.0 99.2 22.6 58.4 21.7 12.6 19.9 57.9 53.0 49.4 28.0 30.6 32.6 56.5 63.1 42.6 93.4 71.5 29.1 57.1 33.9 37.1 28.1 91.4 20.5 21.4 33.8 8.8 14.9 11.3 9.7 9.3 9.5 14.1 8.5 6.8 8.3 19.2 16.9 26.9 7.9 13.0 11.7 43.7 46.9 43.6 49.0 38.8 44.4 43.4 42.0 44.8 41.0 46.4 60.9 47.8 28.9 36.5 98.6 29.1 136.1 143.0 41.3 113.8 36.3 64.7 53.2 123.1 38.6 53.7 23.9 29.2 29.2 28.7 117.2 64.6 89.8 516.2 78.9 44.0 59.9 54.0 60.0 169.8 94.3 46.1 57.4 37.8 127.3 52.6 29.4 56.7 58.8 24.9 122.8 197.7 45.6 28.5 35.6 128.3 330.7 42.3 48.2 74.7 62.8 67.7 51.9 30.9 130.7 309.0 109.9 90.1 57.6 45.8 325.6 125.8 46.1 36.2 51.9 39.5 32.4 72.8 159.9 73.4 139.3 170.5 39.3 34.1 90.0 66.0 303.2 LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 62.1;Leydig cells: 27.1;Melanocytes: 33.8;Peritubular cells: 17.3;Skeletal myocytes: 33.0" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 7.7;ASC TERT1: 25.3;HHSteC: 19.8;HSkMC: 10.6;LHCN-M2: 13.4" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" 23.3 6.6 0.4 2.5 0.4 0.5 16.0 1.5 1.3 22.4 2.6 15.1 1.8 29.7 3.7 4.5 18.2 3.6 7.2 0.6 0.6 1.0 0.1 3.5 0.5 0.5 0.3 21.0 1.1 0.3 1.7 0.7 0.4 6.1 2.1 0.4 5.5 5.8 4.8 10.6 7.2 9.1 0.2 0.2 8.2 1.5 0.5 0.4 4.2 5.6 0.3 9.7 16.1 0.7 0.0 0.1 0.2 0.3 7.7 25.3 0.3 2.8 4.0 0.3 1.4 0.2 0.1 0.2 0.3 4.6 0.1 0.3 0.1 0.0 0.4 0.2 0.2 0.5 0.2 0.2 19.8 0.2 0.2 10.6 0.1 0.6 0.0 0.2 0.1 0.4 0.3 0.1 13.4 0.1 0.3 0.6 0.6 0.1 0.1 0.1 1.7 0.3 0.0 0.2 0.8 0.3 0.4 0.3 0.8 0.1 0.2 0.3 0.3 2.4 0.2 2.7 0.1 0.2 0.2 0.3 1.5 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.0 0.4 0.4 1.5 1.3 0.6 0.6 0.5 0.3 0.4 0.2 0.5 0.7 4.0 0.0 1.8 0.0 0.1 6.6 2.1 0.0 0.0 2.1 0.5 0.8 1.5 0.0 0.6 0.0 2.1 0.1 0.2 0.0 0.0 0.0 1.0 0.5 11.0 3.7 1.2 0.0 0.1 0.0 0.2 62.1 0.5 0.4 1.3 0.2 1.4 0.1 0.4 1.7 0.3 0.3 0.0 0.6 8.3 0.5 27.1 1.1 33.8 1.9 0.1 0.2 1.0 0.0 0.1 0.0 0.1 17.3 0.4 1.4 0.1 0.3 0.0 1.0 0.0 33.0 2.8 0.4 0.3 0.5 7.0 0.1 1.1 1.2 0.1 1.3 LRSAM1 "CMT2P, FLJ31641, RIFLE, TAL" ENSG00000148356 "Leucine rich repeat and sterile alpha motif containing 1" Q6UWE0 9 127451489-127503499 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 32.0;Excitatory neurons: 28.6;Inhibitory neurons: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021403, HPA021844, CAB037304" Supported Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB037304: AB_2138198, HPA021403: AB_1853366, HPA021844: AB_1853368" "unprognostic (8.83e-2)" "unprognostic (3.13e-1)" "unprognostic (7.48e-3)" "unprognostic (4.15e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (1.64e-1)" "unprognostic (5.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.72e-2)" "prognostic favorable (6.78e-6)" "unprognostic (1.27e-1)" "prognostic favorable (5.72e-4)" "unprognostic (1.94e-2)" "unprognostic (3.26e-1)" "unprognostic (9.07e-2)" "unprognostic (3.33e-2)" 7.2 9.8 8.6 3.4 8.6 2.0 7.3 7.3 12.5 10.7 5.2 16.5 3.4 9.0 5.9 8.7 7.8 3.9 17.3 8.8 8.8 9.0 8.8 7.4 4.5 11.1 7.6 10.7 5.7 6.9 9.0 3.4 11.4 9.1 2.6 2.3 7.5 5.6 13.5 21.2 9.1 5.0 7.0 9.5 9.5 4.3 7.9 3.4 8.8 7.2 3.2 12.3 10.2 9.0 5.7 10.8 4.8 10.7 9.8 9.1 8.3 5.3 8.1 10.0 7.6 8.9 5.9 9.8 5.9 9.9 3.6 18.7 7.8 13.3 3.8 11.5 5.3 5.2 9.0 10.2 9.4 6.2 7.3 6.1 7.9 6.1 12.2 10.7 11.2 7.6 4.8 7.6 4.5 17.6 3.9 4.5 4.7 17.4 9.3 7.1 5.6 18.4 11.5 5.1 9.8 9.2 4.1 12.6 8.8 4.3 26.5 3.2 10.2 4.6 5.6 4.2 2.5 6.2 7.9 1.1 9.1 4.5 2.6 18.5 4.8 21.3 3.7 6.5 4.7 3.7 2.8 3.5 6.1 2.7 1.1 1.4 4.0 1.3 6.8 3.6 2.3 3.8 8.6 8.6 7.3 12.5 8.8 8.8 11.1 7.6 11.4 7.0 7.9 9.0 5.3 9.6 3.9 32.0 5.1 1.1 3.1 2.9 4.6 6.7 5.2 5.0 20.4 4.3 7.3 0.0 6.2 5.0 5.3 6.0 5.9 7.1 0.6 3.6 4.7 4.8 1.2 2.5 28.6 1.4 2.1 4.9 12.2 4.6 9.5 6.6 3.3 7.1 6.3 11.8 26.9 5.8 14.2 5.6 3.7 1.2 2.8 7.4 3.6 10.3 7.4 4.7 3.1 18.1 21.0 4.7 5.0 5.3 3.9 5.0 6.6 5.8 6.0 5.2 0.0 5.1 6.0 5.7 3.6 5.8 2.7 7.0 5.6 3.9 4.8 3.3 LSM14B "bA11M20.3, C20orf40, FAM61B, FLJ25473, FT005, LSM13, RAP55B" ENSG00000149657 "LSM family member 14B" Q9BX40 20 62122461-62135374 "Predicted intracellular proteins" "Translation regulation" "Developmental protein, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 16 "Early spermatids: 215.2;Late spermatids: 560.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041274, HPA061189" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA041274: AB_2677388, HPA061189: AB_2684448" "unprognostic (2.24e-1)" "unprognostic (2.35e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-2)" "unprognostic (1.20e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.61e-5)" "unprognostic (4.99e-2)" "unprognostic (2.28e-1)" "unprognostic (5.43e-2)" "unprognostic (4.93e-3)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (6.61e-2)" "unprognostic (2.00e-1)" "unprognostic (4.53e-3)" "unprognostic (1.98e-1)" 19.7 23.9 29.3 21.0 30.1 26.7 19.8 39.5 34.5 27.5 21.6 27.4 23.4 31.2 14.2 31.6 25.7 14.5 37.7 32.3 24.1 19.0 24.4 19.3 23.5 24.2 26.6 37.4 30.4 21.3 24.9 14.9 25.9 22.0 14.3 31.2 23.7 17.4 71.6 34.6 22.8 17.6 23.2 21.7 23.3 51.9 27.1 28.8 20.9 45.3 17.8 26.5 27.3 27.2 44.4 41.6 65.0 62.5 29.0 30.3 55.3 46.0 34.1 93.7 40.9 123.4 30.1 46.5 51.7 31.9 67.9 62.9 31.5 39.6 46.4 19.2 22.9 112.3 57.8 74.3 40.0 48.6 65.1 26.1 70.4 39.1 36.1 36.7 24.3 53.8 61.4 32.7 33.0 58.7 81.2 72.7 40.2 70.8 61.0 104.3 128.5 36.9 25.5 51.7 88.8 77.0 83.9 73.5 61.3 37.5 91.6 60.9 31.8 132.9 90.0 69.1 47.3 40.8 52.1 56.8 58.5 31.7 43.4 0.0 0.4 2.2 0.3 0.3 0.1 0.5 0.2 0.4 0.3 0.5 0.2 0.3 0.6 0.0 0.2 0.4 0.2 0.1 29.3 30.1 39.5 34.5 32.3 24.1 24.2 26.6 25.9 23.2 27.1 27.2 8.6 9.6 6.8 9.1 7.3 9.7 3.5 4.7 5.2 15.1 8.4 7.1 22.8 7.2 7.9 1.8 8.4 6.4 15.3 13.5 1.9 5.0 215.2 13.3 14.1 8.0 13.9 9.5 6.2 5.3 6.0 7.5 8.2 10.3 5.1 14.8 5.0 11.6 8.6 8.4 6.8 12.0 6.1 13.2 6.8 560.0 13.4 8.8 3.6 7.5 8.2 17.2 7.2 5.0 8.4 7.1 8.2 15.8 4.7 9.2 9.7 6.7 12.1 20.3 0.0 9.5 6.4 11.2 23.1 7.6 10.1 5.2 6.9 13.4 12.4 3.0 LSP1 WP34 ENSG00000130592 "Lymphocyte specific protein 1" P33241 11 1850904-1892267 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 224.7;lymphoid tissue: 245.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 492.2;Langerhans cells: 553.6;monocytes: 1505.6;NK-cells: 352.2;Plasma cells: 338.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 278.5;HDLM-2: 978.9;Karpas-707: 215.4;RPMI-8226: 500.2;U-937: 173.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017781, HPA019693" Enhanced NA NA 1600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB017781: , HPA019693: AB_1853387" "unprognostic (7.53e-3)" "prognostic favorable (3.56e-4)" "unprognostic (4.35e-2)" "prognostic favorable (2.54e-4)" "prognostic unfavorable (5.35e-4)" "unprognostic (1.43e-3)" "unprognostic (3.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.72e-1)" "unprognostic (1.03e-3)" "unprognostic (3.29e-1)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.20e-2)" 75.6 224.7 2.1 148.8 2.6 167.3 51.2 2.4 6.4 63.8 5.3 39.2 33.6 36.8 3.8 42.5 41.7 32.6 48.2 3.8 3.4 6.4 12.1 49.8 154.8 6.0 2.6 5.3 10.7 3.8 7.4 21.8 4.5 13.4 22.3 1.0 52.8 8.1 28.4 98.0 76.6 12.5 4.3 245.0 52.1 8.1 6.0 65.5 24.7 29.4 85.0 83.7 51.4 11.6 0.3 1.2 0.0 0.0 41.0 125.2 0.4 0.0 0.0 0.0 0.0 0.1 0.2 278.5 1.5 0.2 0.3 0.4 0.0 0.0 0.0 978.9 0.0 0.5 0.2 0.4 7.9 1.0 0.9 32.0 0.5 0.1 1.3 0.4 0.1 2.2 0.9 215.4 24.7 0.1 19.6 28.2 0.5 0.0 0.0 1.1 13.6 500.2 0.0 0.0 0.4 3.3 0.2 0.0 0.3 0.0 0.3 0.9 0.5 0.7 4.6 0.3 0.8 1.0 0.7 38.4 0.4 173.0 0.3 365.1 803.6 785.5 384.3 863.3 222.6 452.1 249.1 346.8 896.6 298.8 161.3 260.8 1574.3 279.6 888.2 669.7 491.4 1293.0 2.1 2.6 2.4 6.4 3.8 3.4 6.0 2.6 4.5 4.3 6.0 11.6 18.3 16.0 7.9 0.0 312.8 118.3 14.0 43.0 76.8 0.8 3.9 4.3 2.7 8.6 37.6 3.7 0.0 3.6 295.4 0.4 1.9 1.3 3.4 1.2 13.3 11.4 1.2 40.6 0.2 8.9 4.4 160.4 15.3 1.4 12.6 0.9 11.0 2.3 492.2 1.7 0.2 0.8 16.2 118.4 553.6 7.8 89.8 310.9 65.8 0.0 1505.6 0.2 352.2 0.5 0.1 1.4 1.4 30.1 338.4 1.1 1.2 12.9 36.6 1.0 0.0 182.1 15.9 0.4 1.3 16.7 114.7 6.4 310.1 92.7 3.2 67.3 LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 335.6;Ductal cells: 260.5;Exocrine glandular cells: 278.9;Pancreatic endocrine cells: 336.0;Paneth cells: 273.6;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 500.5;CACO-2: 215.6;CAPAN-2: 225.3;HaCaT: 203.9;OE19: 300.4;RT4: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Supported "Plasma membrane" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" 15.7 31.3 15.7 17.8 13.6 3.6 25.4 13.2 14.7 20.4 39.0 96.9 85.0 14.4 13.9 60.0 29.7 36.4 7.7 12.5 13.2 28.9 144.8 30.0 14.4 17.1 14.8 6.4 114.2 16.8 27.3 46.9 15.5 25.6 43.7 8.6 69.4 18.5 4.4 51.9 75.0 5.3 12.9 17.9 133.1 27.2 17.7 6.6 32.9 2.7 14.1 29.9 29.3 14.8 500.5 8.1 0.7 1.0 1.4 0.5 86.8 1.2 1.9 2.2 1.6 215.6 225.3 19.6 73.0 1.3 7.2 203.9 44.3 75.0 0.3 30.1 82.6 0.2 6.5 96.1 1.7 0.3 0.9 1.0 81.2 2.0 24.2 1.0 0.8 0.6 80.2 17.2 1.1 177.4 0.9 1.1 69.0 300.4 3.2 3.8 0.8 54.6 46.2 198.2 37.7 1.4 40.9 130.5 35.8 21.7 112.5 2.6 0.4 3.9 44.7 3.1 2.2 27.2 52.5 45.7 3.4 0.8 12.4 6.4 0.2 0.1 2.5 0.0 2.6 4.3 5.8 5.4 0.1 3.0 4.2 4.9 0.0 5.6 0.0 0.2 4.1 2.9 15.7 13.6 13.2 14.7 12.5 13.2 17.1 14.8 15.5 12.9 17.7 14.8 38.2 16.0 21.7 0.3 26.3 51.7 123.4 90.7 50.1 2.1 60.9 49.7 5.6 78.6 71.2 36.8 16.7 210.3 4.7 335.6 11.7 260.5 9.4 41.7 27.4 44.6 56.4 3.2 0.8 278.9 93.0 11.9 214.1 61.5 31.1 30.3 20.3 89.7 21.7 0.0 0.9 145.5 73.2 2.2 14.3 2.9 6.5 4.6 14.2 22.5 7.2 11.5 3.1 1.5 0.8 336.0 273.6 3.4 41.1 113.6 117.8 24.6 43.8 12.3 0.0 4.1 24.4 7.9 19.1 57.2 51.7 248.0 24.3 3.4 124.2 206.3 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LTA4H ENSG00000111144 "Leukotriene A4 hydrolase" P09960 12 96000753-96043520 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Leukotriene biosynthesis, Lipid metabolism" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 207.2;Kupffer cells: 255.8;monocytes: 245.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008399, CAB015221, HPA017017" Supported Approved Nucleoplasm,Cytosol NA NA 86000000 "Cluster 7: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB015221: , HPA008399: AB_1852816, HPA017017: AB_1852818" "prognostic favorable (9.79e-4)" "unprognostic (6.62e-2)" "unprognostic (6.04e-2)" "unprognostic (1.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (4.25e-3)" "prognostic favorable (8.96e-4)" "unprognostic (1.72e-1)" "unprognostic (1.75e-2)" "unprognostic (3.38e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-1)" 40.2 66.9 24.6 64.5 25.5 180.4 53.6 29.4 30.6 55.6 33.8 48.2 78.1 51.1 38.4 110.1 61.7 40.3 35.5 25.0 27.8 58.1 43.9 190.8 64.1 26.3 25.4 110.5 54.9 53.3 37.4 27.4 26.0 41.1 49.6 36.9 41.2 40.9 45.0 67.8 60.5 58.3 25.7 57.8 46.6 19.9 28.1 49.2 49.4 45.0 96.4 51.9 52.7 33.0 85.2 90.4 123.5 73.4 104.2 115.1 53.8 33.7 101.8 67.5 78.1 66.6 72.0 190.0 42.0 51.9 52.8 108.3 103.4 140.1 92.3 63.3 97.0 68.5 54.3 81.8 61.8 35.7 39.4 110.1 118.4 91.9 114.5 305.3 134.9 101.1 42.9 32.5 98.7 59.2 96.7 115.0 145.8 100.7 115.5 88.9 90.5 109.7 125.7 107.7 63.9 75.5 64.2 80.4 78.3 95.1 98.7 44.7 49.0 28.3 47.6 40.2 38.2 42.8 79.4 85.4 19.1 66.2 22.3 4.4 662.9 17.7 33.4 699.2 63.4 126.1 46.6 43.4 282.3 157.5 65.0 50.5 46.0 120.4 638.8 70.4 51.2 591.5 24.6 25.5 29.4 30.6 25.0 27.8 26.3 25.4 26.0 25.7 28.1 33.0 32.8 38.5 135.0 15.3 82.8 51.9 64.8 96.6 52.3 21.4 41.8 41.1 25.3 25.8 110.2 38.6 33.3 29.3 47.9 17.6 74.3 42.9 74.3 18.4 20.8 38.2 21.6 50.5 21.3 28.0 28.2 29.7 38.2 27.3 7.6 31.5 57.8 21.7 207.2 11.8 18.5 40.4 40.7 255.8 76.6 16.4 36.7 183.3 21.4 10.3 245.5 35.5 26.8 19.6 17.5 20.8 27.1 41.0 40.1 35.4 73.2 69.3 45.0 55.6 6.6 26.7 35.4 46.9 11.6 108.0 74.9 20.8 39.1 32.9 70.4 49.7 LTB "p33, TNFC, TNFSF3" ENSG00000227507 "Lymphotoxin beta" Q06643 6 31580525-31582522 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 66.7;lymphoid tissue: 229.2" "Cell type enhanced" "Detected in many" "B-cells: 1087.8;dendritic cells: 183.5;Ductal cells: 280.4;Pancreatic endocrine cells: 296.2;T-cells: 554.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 35.6;Daudi: 127.4;HDLM-2: 82.2;HMC-1: 38.1;NB-4: 62.3;REH: 58.6;U-698: 90.8" "Not detected" "Not detected" HPA048884 Approved Approved Centrosome NA NA "Cluster 30: Non-specific - Translation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA048884: AB_2680543" "unprognostic (1.43e-2)" "unprognostic (3.89e-2)" "unprognostic (7.29e-2)" "prognostic favorable (2.36e-6)" "unprognostic (2.91e-3)" "prognostic favorable (1.74e-4)" "unprognostic (1.45e-1)" "unprognostic (9.49e-3)" "unprognostic (1.42e-3)" "unprognostic (4.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (8.91e-2)" "unprognostic (4.92e-2)" "unprognostic (6.56e-3)" "unprognostic (1.99e-1)" 3.5 0.7 0.2 82.6 0.3 19.1 1.3 0.1 0.5 1.3 0.2 6.7 8.2 1.2 0.0 4.3 1.2 4.8 1.1 0.1 0.2 10.3 4.8 8.7 103.9 0.4 0.2 0.4 2.5 0.2 0.7 0.9 0.3 2.4 2.7 0.0 4.2 0.3 1.0 2.2 66.7 1.9 0.2 229.2 13.9 0.2 0.3 83.3 3.8 1.4 47.6 8.7 1.4 0.2 18.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 35.6 127.4 1.8 0.0 0.2 0.0 0.0 0.0 0.0 82.2 0.0 1.4 0.0 0.0 0.0 0.4 38.1 0.0 0.0 0.0 0.3 0.0 0.6 0.8 0.0 0.0 0.0 0.0 18.5 62.3 0.0 0.0 0.0 58.6 0.0 11.4 32.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 6.7 0.0 0.0 0.5 0.0 0.0 0.0 0.8 90.8 0.0 0.0 0.0 79.2 9.2 542.5 95.7 55.9 646.7 1027.3 924.3 419.4 14.5 1021.9 713.6 317.0 327.8 142.5 94.5 412.0 672.0 308.9 0.2 0.3 0.1 0.5 0.1 0.2 0.4 0.2 0.3 0.2 0.3 0.2 3.0 0.0 9.0 1.3 1087.8 16.3 0.5 45.7 2.2 0.7 2.9 3.7 0.5 2.8 4.7 90.1 0.0 0.9 183.5 0.9 1.9 280.4 3.5 2.2 2.0 8.4 0.0 11.2 0.9 113.1 0.3 6.3 3.1 1.5 14.0 0.1 10.8 3.5 10.1 0.0 0.9 0.4 160.7 31.0 112.1 0.2 0.6 49.8 42.7 0.0 72.3 1.8 99.9 0.0 0.3 296.2 1.6 0.0 13.6 3.0 0.0 11.6 0.9 0.2 6.6 1.3 4.3 0.4 1.2 1.2 12.4 0.3 554.0 0.3 3.6 0.3 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 966.4;Fibroblasts: 2136.1;Leydig cells: 401.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 1991.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 161.5 133.5 0.6 68.1 0.7 0.3 153.2 0.6 5.6 199.8 4.2 85.0 56.1 301.0 88.3 75.7 59.2 739.0 183.8 0.7 0.9 85.0 34.6 211.4 41.3 0.9 0.8 92.9 72.9 26.3 5.3 535.9 0.8 115.2 133.0 5.7 14.3 67.4 9.6 20.0 90.6 354.5 0.7 4.8 47.1 17.5 1.3 13.4 30.8 73.0 80.3 486.0 39.2 0.8 0.0 0.3 6.9 0.0 237.4 115.9 0.7 400.8 1991.0 16.0 24.3 0.0 0.1 0.0 0.0 339.9 0.0 0.6 0.0 0.0 5.4 0.0 0.0 0.0 21.5 0.0 183.7 0.6 0.1 160.5 0.0 33.7 1.0 0.9 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 1.2 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.3 14.9 0.1 0.0 10.8 16.3 0.0 0.0 0.0 17.0 4.5 14.3 0.0 0.2 0.0 0.0 8.8 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.6 5.6 0.7 0.9 0.9 0.8 0.8 0.7 1.3 0.8 77.5 12.8 30.9 0.0 0.6 97.6 1.2 0.8 3.4 0.2 9.4 8.6 15.2 0.0 5.0 0.0 2.1 44.9 4.0 0.1 0.0 0.7 3.5 27.0 966.4 27.2 0.0 0.0 0.0 0.0 38.9 2136.1 8.6 15.2 18.3 0.0 55.0 0.3 63.6 0.0 0.2 0.3 0.0 0.3 143.5 8.7 401.7 9.5 117.4 16.9 1.0 86.9 0.0 0.0 0.0 2.1 0.0 44.8 6.3 4.9 0.4 0.3 0.8 3.0 0.0 39.1 165.5 0.2 0.9 5.9 100.2 84.0 14.5 27.4 0.0 4.1 LURAP1L "bA3L8.2, C9orf150, FLJ38505, LRAP35b, MGC46502" ENSG00000153714 "Leucine rich adaptor protein 1 like" Q8IV03 9 12775020-12823060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 90.2;Paneth cells: 88.8;Prostatic glandular cells: 104.3;Urothelial cells: 140.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 100.6;hTERT-HME1: 81.9;T-47d: 118.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024407 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Nucleoli Nucleoplasm "HPA024407: AB_10603780" "unprognostic (1.20e-1)" "unprognostic (2.15e-1)" "unprognostic (7.45e-2)" "unprognostic (1.73e-2)" "unprognostic (2.08e-2)" "unprognostic (5.61e-3)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" "unprognostic (2.92e-1)" "unprognostic (1.06e-2)" "unprognostic (1.56e-2)" "unprognostic (3.67e-2)" "unprognostic (5.68e-3)" "unprognostic (4.38e-1)" "unprognostic (5.67e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-2)" 14.6 9.3 3.4 5.5 4.6 0.1 10.6 11.8 6.1 10.9 2.5 19.9 4.1 6.2 3.3 4.6 6.6 11.8 4.4 3.5 4.2 5.4 32.2 25.0 3.9 5.2 4.6 4.2 19.6 0.8 5.5 21.0 5.0 6.9 9.4 4.7 27.7 6.7 2.5 12.2 9.2 8.3 5.7 10.4 12.5 0.5 4.7 1.2 8.7 3.4 2.0 12.1 12.4 5.8 2.2 7.1 0.0 2.3 11.0 15.1 0.0 3.9 20.2 5.1 5.4 0.0 2.6 0.0 1.5 20.6 24.3 3.0 0.0 0.4 3.9 0.0 0.8 1.1 6.7 4.0 100.6 0.0 0.0 6.0 9.7 17.4 81.9 8.6 3.3 0.0 0.0 25.8 3.1 1.8 0.0 0.0 0.1 9.6 7.8 0.0 1.3 0.1 20.7 1.2 15.5 1.5 4.7 2.9 3.8 1.7 118.5 0.4 1.3 4.5 0.7 11.7 2.8 0.1 0.0 0.0 7.2 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.4 4.6 11.8 6.1 3.5 4.2 5.2 4.6 5.0 5.7 4.7 5.8 9.6 9.6 18.4 1.3 0.7 90.2 34.4 19.3 5.2 10.2 60.1 26.2 7.1 20.0 40.2 1.8 2.1 1.0 0.5 58.7 7.9 66.6 5.0 11.5 3.2 7.8 26.7 0.0 18.4 11.8 2.7 19.7 10.2 29.2 10.8 12.9 1.8 30.2 0.6 18.5 41.6 12.8 24.4 0.0 8.4 0.8 9.3 2.3 26.6 6.5 0.0 4.3 0.0 8.0 44.1 27.5 88.8 3.0 0.0 104.3 20.7 5.5 16.1 10.2 39.5 8.0 47.4 0.1 0.6 2.9 64.4 1.1 1.9 1.3 49.5 140.4 LY6D E48 ENSG00000167656 "Lymphocyte antigen 6 family member D" Q14210 8 142784882-142786539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2074.3;skin 1: 850.4;vagina: 491.2" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 1171.6;Squamous epithelial cells: 1913.0;Suprabasal keratinocytes: 3866.1" "Group enriched" "Detected in many" 7 "cervical cancer: 409.8;head and neck cancer: 444.6;urothelial cancer: 242.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "A-431: 162.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024755, HPA064317" Enhanced NA NA 210000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA024755: AB_1853410, HPA064317: AB_2685244" "unprognostic (2.13e-2)" "unprognostic (7.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-2)" "unprognostic (8.97e-2)" "unprognostic (1.51e-2)" "unprognostic (3.84e-1)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (8.68e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.50e-1)" "unprognostic (3.97e-1)" "unprognostic (5.40e-4)" "unprognostic (1.06e-1)" 1.7 47.6 0.6 0.2 0.6 0.0 20.4 0.5 1.4 297.4 0.5 0.9 0.0 0.3 0.0 2074.3 1.0 1.4 0.8 0.6 0.5 0.3 0.8 0.5 0.0 0.5 0.5 0.5 1.0 0.0 1.0 2.5 0.5 15.3 0.2 0.0 235.4 0.3 2.6 850.4 0.5 0.0 0.5 0.5 12.4 0.4 0.5 4.6 0.4 0.0 75.6 65.2 491.2 0.7 162.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 6.0 0.0 1.3 0.0 0.2 0.0 0.0 4.0 11.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 1.2 4.0 0.2 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 1.4 0.6 0.5 0.5 0.5 0.5 0.5 0.5 0.7 0.1 3.2 0.0 0.0 0.0 1171.6 9.4 244.9 138.3 0.0 14.8 14.1 0.2 0.0 154.0 1.8 0.0 0.9 0.1 0.4 1.9 1.1 0.0 0.4 0.1 10.7 0.0 0.0 0.3 0.2 5.7 9.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 22.4 0.0 137.3 0.0 0.0 0.8 163.7 0.0 0.0 0.0 0.0 0.0 0.1 7.0 0.0 0.0 2.5 18.9 0.0 1.2 12.2 0.0 0.0 0.6 16.1 0.0 0.0 1913.0 3866.1 8.2 4.0 0.0 0.4 164.6 LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.5;intestine: 12.0;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in some" "B-cells: 244.0;dendritic cells: 36.2;Melanocytes: 71.2;Plasma cells: 102.5;T-cells: 44.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 112.9;MAIT T-cell: 113.5;memory B-cell: 56.1;memory CD4 T-cell: 97.6;memory CD8 T-cell: 109.8;naive B-cell: 52.8;naive CD4 T-cell: 109.6;naive CD8 T-cell: 112.3;plasmacytoid DC: 72.8;T-reg: 80.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 14.3;JURKAT: 14.1;Karpas-707: 28.0;U-266/70: 70.7;U-266/84: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" NA NA 43000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Centriolar satellite" "HPA050917: AB_2681272" "unprognostic (8.04e-4)" "unprognostic (2.31e-5)" "unprognostic (8.08e-3)" "unprognostic (1.20e-3)" "unprognostic (9.83e-3)" "unprognostic (1.87e-5)" "unprognostic (1.16e-2)" "unprognostic (3.84e-3)" "unprognostic (1.23e-2)" "unprognostic (2.89e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.69e-2)" "unprognostic (9.47e-2)" "unprognostic (3.49e-2)" "unprognostic (6.88e-2)" 2.4 0.9 0.1 13.7 0.2 11.5 2.0 0.1 0.2 0.8 0.2 3.9 4.0 0.6 0.4 0.9 0.9 2.5 0.5 0.1 0.2 1.1 2.3 3.8 30.2 0.3 0.2 0.6 0.2 0.0 0.2 0.3 0.2 1.1 3.8 0.0 7.1 0.4 0.3 0.8 12.0 0.5 0.3 26.7 6.0 0.2 0.2 25.5 1.4 0.2 31.1 3.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 28.0 0.0 0.0 2.3 0.5 0.1 0.8 0.0 1.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 70.7 29.3 0.3 0.0 4.0 0.0 1.2 0.8 0.4 112.9 1.1 113.5 56.1 97.6 109.8 5.2 52.8 109.6 112.3 2.4 22.2 0.8 72.8 80.3 53.5 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.3 0.2 0.2 0.4 0.0 1.8 0.3 244.0 1.0 0.5 0.1 0.0 0.0 0.4 0.8 0.9 0.0 0.0 0.0 0.0 0.1 36.2 0.1 0.0 0.0 0.1 0.1 0.1 0.7 1.2 28.0 0.1 0.2 0.0 1.4 0.5 0.1 0.0 0.0 1.8 0.4 1.9 0.0 0.1 0.0 0.0 3.2 31.9 0.0 0.0 6.3 71.2 1.9 2.1 0.0 22.6 0.0 0.1 0.1 0.0 0.0 102.5 0.2 0.0 0.3 0.0 0.0 0.0 0.5 0.6 0.0 0.1 0.5 1.0 0.1 44.8 0.0 0.3 0.3 LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 570.8;Kupffer cells: 544.6;Langerhans cells: 155.4;Macrophages: 198.5;monocytes: 136.0;Plasma cells: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 627.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 627.0" "Cell line enhanced" "Detected in many" "GAMG: 75.1;Karpas-707: 184.9;RPMI-8226: 94.0;U-87 MG: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" NA NA 250000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA053060: AB_2682029" "unprognostic (2.96e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.38e-11)" "unprognostic (2.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" 28.6 12.4 12.9 42.4 13.5 17.9 24.7 13.1 22.7 12.9 13.8 15.7 12.3 10.5 5.4 9.0 11.1 35.3 9.5 13.0 14.4 13.2 22.8 22.0 47.4 16.3 14.8 22.6 3.7 2.4 8.0 44.9 14.9 6.1 14.5 1.2 11.4 6.7 3.8 4.4 9.9 20.3 14.7 59.6 10.6 4.7 13.9 16.2 7.3 9.8 39.3 30.5 7.9 17.1 1.5 0.0 0.3 0.2 34.5 73.2 0.1 49.5 61.9 13.5 31.1 0.0 0.5 15.9 16.7 32.6 75.1 0.5 0.2 0.6 34.4 17.1 0.3 0.3 0.0 1.8 17.5 2.7 0.9 21.2 0.4 21.9 4.3 2.2 67.2 9.7 0.2 184.9 48.9 0.0 6.5 2.1 0.2 0.0 1.0 6.4 0.0 94.0 2.5 0.0 0.3 0.2 0.0 0.2 6.5 0.3 0.0 3.3 52.1 33.5 2.6 18.0 12.1 48.1 24.7 9.6 92.3 1.0 14.7 13.7 90.2 0.4 0.5 85.1 1.3 26.3 12.8 1.9 45.8 15.1 8.2 2.9 627.0 0.2 71.8 37.6 21.6 30.6 12.9 13.5 13.1 22.7 13.0 14.4 16.3 14.8 14.9 14.7 13.9 17.1 35.1 16.0 10.7 0.0 48.4 13.8 1.2 1.3 0.0 0.2 11.2 4.4 2.4 0.0 9.7 3.7 0.0 2.7 16.3 0.1 0.0 6.8 24.2 0.3 1.0 63.6 0.0 14.1 2.8 7.4 3.1 32.9 0.0 0.3 3.8 0.0 104.2 3.3 570.8 0.0 3.9 0.0 2.0 544.6 155.4 3.1 14.3 198.5 76.5 21.5 136.0 0.0 1.0 0.5 1.1 9.4 0.0 6.8 172.6 0.8 0.0 1.1 5.6 0.2 6.6 20.0 14.0 0.7 0.2 2.2 11.6 6.4 21.8 12.4 0.3 1.4 LYPD3 C4.4A ENSG00000124466 "LY6/PLAUR domain containing 3" O95274 19 43460787-43465608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1066.8;skin 1: 669.3;vagina: 487.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 504.7;Squamous epithelial cells: 811.7;Suprabasal keratinocytes: 2306.1;Syncytiotrophoblasts: 715.8;Urothelial cells: 642.9" "Cancer enhanced" "Detected in many" "cervical cancer: 158.5;head and neck cancer: 235.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 5.5" "Group enriched" "Detected in many" 9 "dendritic cells: 2.6;granulocytes: 2.1;T-cells: 5.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.5;HaCaT: 99.5;MCF7: 114.2;RT4: 108.2;SK-BR-3: 158.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041529, HPA041797, HPA077859" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA 7600000 "Cluster 32: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Vesicles" "HPA041529: AB_2677534, HPA041797: AB_2677679, HPA077859: " "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (2.80e-1)" "unprognostic (2.67e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.20e-1)" "unprognostic (6.99e-2)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (1.07e-3)" "unprognostic (5.13e-2)" "unprognostic (8.79e-2)" "unprognostic (1.11e-1)" "unprognostic (2.96e-3)" 1.7 3.5 0.7 1.7 0.8 6.6 32.1 0.6 1.0 259.1 1.4 1.1 0.5 7.6 1.8 1066.8 3.5 1.3 1.3 0.7 0.9 2.9 1.2 1.6 2.6 0.7 0.8 8.9 1.3 1.8 2.3 12.3 0.7 11.9 0.7 1.0 183.3 1.3 2.8 669.3 1.6 0.8 0.7 2.1 3.3 1.1 0.8 12.2 1.2 0.2 131.9 55.0 487.0 0.7 38.6 0.6 0.2 0.6 0.3 0.0 15.3 1.5 3.9 1.4 1.9 0.5 42.5 0.4 1.7 1.1 5.6 99.5 0.2 4.4 0.7 0.0 0.3 0.7 4.5 0.8 0.4 0.0 0.9 1.7 37.2 0.2 0.3 1.7 0.0 3.1 0.2 0.1 0.1 114.2 0.9 0.0 0.2 24.3 8.3 0.5 0.0 0.2 1.0 108.2 0.1 0.3 0.5 158.9 1.8 4.7 17.7 0.1 0.0 0.0 0.7 0.5 0.7 0.6 3.0 0.1 0.1 0.2 0.1 0.0 0.3 0.0 0.8 0.0 1.1 0.1 2.9 1.1 2.6 0.0 5.5 4.7 2.1 0.0 0.0 0.3 0.9 1.2 0.7 0.8 0.6 1.0 0.7 0.9 0.7 0.8 0.7 0.7 0.8 0.7 0.9 0.0 1.1 0.0 1.3 504.7 102.5 161.2 111.0 0.7 66.6 38.0 0.6 2.8 72.6 14.7 0.0 96.5 2.1 0.9 1.9 1.6 0.1 4.5 4.4 7.5 0.0 0.4 0.0 0.2 87.2 18.1 3.6 24.5 5.7 0.5 0.0 0.3 14.0 3.3 0.1 2.2 24.4 0.3 139.8 0.0 0.6 23.2 147.7 0.0 0.7 4.5 0.0 0.0 0.2 4.7 0.2 0.4 0.0 40.4 0.3 0.7 5.7 0.5 0.0 1.5 10.5 0.1 0.9 811.7 2306.1 715.8 9.6 0.5 1.1 642.9 LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 33.0;Late spermatids: 81.8;Melanocytes: 17.8;Syncytiotrophoblasts: 21.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.5;BEWO: 5.0;HaCaT: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA042511: AB_10794279, HPA054670: AB_2682567" "unprognostic (4.27e-3)" "prognostic favorable (5.84e-4)" "unprognostic (4.63e-2)" "unprognostic (8.42e-3)" "unprognostic (4.80e-2)" "unprognostic (2.91e-3)" "unprognostic (3.96e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.83e-3)" "unprognostic (8.30e-2)" "unprognostic (2.02e-1)" "unprognostic (7.53e-3)" "unprognostic (4.08e-2)" 1.1 0.6 2.6 1.4 2.5 0.1 2.9 1.8 6.0 9.3 0.0 2.3 0.1 0.9 1.4 11.4 0.8 1.1 1.5 3.0 2.9 3.0 0.4 4.0 0.7 6.8 3.2 0.4 0.3 0.6 1.6 1.0 6.6 1.3 0.8 2.0 3.1 0.8 0.2 50.6 1.2 1.1 1.7 4.8 1.0 3.8 4.1 0.9 1.4 0.4 1.7 1.9 9.0 4.1 3.5 0.0 0.2 0.0 0.0 0.0 5.0 0.0 0.0 0.5 0.6 0.4 1.2 0.2 0.7 0.4 1.4 5.2 0.0 0.7 0.3 0.6 0.0 0.1 0.4 0.0 1.5 0.1 0.0 1.7 1.5 0.2 0.7 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.3 1.9 1.2 0.0 0.0 0.0 0.3 0.6 0.2 0.1 0.7 0.7 0.0 1.1 0.4 0.1 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.1 2.6 2.5 1.8 6.0 3.0 2.9 6.8 3.2 6.6 1.7 4.1 4.1 0.5 0.0 0.0 4.6 0.0 3.6 2.6 1.6 4.0 1.4 1.8 1.5 0.7 0.0 0.4 0.0 0.0 1.6 0.1 3.7 3.9 0.6 33.0 0.2 0.1 3.1 0.0 0.0 7.7 0.9 8.4 1.2 0.0 0.2 0.0 0.5 0.7 0.0 2.4 0.0 8.8 1.9 0.0 0.6 0.8 81.8 0.3 0.5 17.8 1.0 0.0 0.9 0.0 9.5 7.8 0.3 2.3 1.2 0.0 1.4 0.2 0.0 1.4 0.9 0.0 1.0 0.2 9.9 2.6 3.7 2.8 21.6 0.1 0.1 0.8 6.2 LYPD6B "CT116, LYPD7" ENSG00000150556 "LY6/PLAUR domain containing 6B" Q8NI32 2 149038107-149215262 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 95.5" "Cell type enhanced" "Detected in many" "Early spermatids: 245.7;Gastric mucus-secreting cells: 87.7;Inhibitory neurons: 77.8;Late spermatids: 118.5;Suprabasal keratinocytes: 69.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 64.8;LHCN-M2: 102.3;NB-4: 34.7;RT4: 54.7;SK-BR-3: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049239 Uncertain "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "HPA049239: AB_2680688" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (3.12e-3)" "unprognostic (1.64e-1)" "unprognostic (3.37e-1)" "unprognostic (2.01e-2)" "unprognostic (6.27e-2)" "unprognostic (3.64e-2)" "unprognostic (7.95e-3)" "unprognostic (2.59e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-3)" 0.3 0.2 3.5 0.4 2.5 0.2 16.4 1.6 5.3 2.8 1.6 1.7 2.6 0.9 1.2 4.1 23.4 37.3 0.0 4.3 4.1 20.5 0.9 1.7 0.4 2.3 7.3 0.4 12.3 16.1 0.4 0.8 3.0 11.1 3.3 1.0 5.8 15.2 0.2 95.5 1.2 0.3 1.9 2.8 41.3 34.1 8.0 0.3 0.2 0.0 1.9 14.2 6.3 2.1 1.4 0.0 0.0 1.5 0.0 0.1 0.1 8.0 1.5 6.6 2.5 1.0 0.0 0.0 0.0 64.8 0.0 14.0 1.5 1.3 20.6 0.0 7.4 0.0 1.9 0.0 0.2 0.0 0.1 0.6 21.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 102.3 24.3 0.0 34.7 2.0 14.6 0.3 0.0 0.4 4.3 3.2 54.7 3.9 0.1 0.4 32.1 0.0 6.3 4.8 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.8 13.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 2.5 1.6 5.3 4.3 4.1 2.3 7.3 3.0 1.9 8.0 2.1 0.5 0.0 2.0 2.3 5.5 29.8 21.0 30.6 6.2 0.0 23.4 17.1 1.4 42.9 23.9 46.0 0.0 0.1 0.1 4.0 7.9 12.4 245.7 5.2 0.3 1.0 2.4 2.7 4.6 19.1 0.7 0.8 87.7 5.7 0.0 0.4 0.0 0.1 0.1 0.0 77.8 3.9 8.2 0.0 2.8 118.5 2.1 0.4 5.4 0.0 0.6 0.0 0.0 0.0 0.4 30.9 6.0 0.0 4.5 40.6 5.7 0.2 21.4 0.0 0.0 0.0 1.3 4.2 1.7 3.5 69.0 0.3 1.1 0.0 3.5 53.7 LYVE1 "LYVE-1, XLKD1" ENSG00000133800 "Lymphatic vessel endothelial hyaluronan receptor 1" Q9Y5Y7 11 10556966-10611689 "Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 126.4;placenta: 149.3" "Group enriched" "Detected in many" 4 "Hepatic stellate cells: 238.8;Hofbauer cells: 807.4;Kupffer cells: 338.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HUVEC TERT2: 81.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.8" "CAB025860, HPA042953" Supported NA NA 3300000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB025860: , HPA042953: AB_2678238" "unprognostic (9.83e-2)" "unprognostic (1.52e-1)" "unprognostic (1.87e-1)" "unprognostic (3.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.53e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.98e-5)" "unprognostic (1.67e-2)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.43e-3)" 126.4 68.9 2.7 19.3 3.5 0.9 37.3 2.0 5.1 17.6 8.9 19.9 13.3 8.1 5.7 26.2 23.0 20.2 13.5 2.9 2.4 8.1 44.2 23.8 8.4 3.0 2.2 11.8 4.9 2.3 2.7 149.3 3.1 4.0 20.0 0.3 5.4 11.2 5.0 7.1 17.6 67.1 2.1 61.6 10.5 4.3 3.3 1.7 13.5 27.4 3.0 35.1 6.8 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 81.6 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 3.5 2.0 5.1 2.9 2.4 3.0 2.2 3.1 2.1 3.3 3.2 5.7 0.0 2.8 8.1 2.1 3.7 0.1 0.0 0.0 0.0 0.5 0.3 4.6 8.6 0.0 0.0 0.0 5.3 0.3 0.0 0.0 0.0 1.0 0.0 0.2 102.7 0.0 5.3 0.8 0.0 5.7 3.4 0.0 0.0 1.3 0.0 238.8 4.5 807.4 0.0 0.4 0.0 0.0 338.1 10.7 2.3 3.7 86.0 7.2 12.2 0.1 0.0 0.0 0.5 0.6 0.0 0.0 0.4 2.7 0.2 0.0 0.0 1.5 0.0 13.1 3.4 6.8 0.0 0.0 1.4 3.3 11.1 1.4 0.7 0.0 0.2 MAB21L3 "C1orf161, FLJ38716" ENSG00000173212 "Mab-21 like 3" Q8N8X9 1 116111755-116135240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.3;esophagus: 7.0;skin 1: 6.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Alveolar cells type 2: 48.3;Club cells: 18.5;granulocytes: 17.7;Oligodendrocytes: 31.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 4.6;EFO-21: 13.4;RT4: 14.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "cerebellum: 6.2" HPA039551 Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "HPA039551: AB_2676565" "unprognostic (9.25e-3)" "unprognostic (3.47e-3)" "unprognostic (1.44e-3)" "unprognostic (5.23e-5)" "unprognostic (2.22e-1)" "unprognostic (2.06e-2)" "unprognostic (5.36e-2)" "unprognostic (3.75e-3)" "unprognostic (1.21e-1)" "unprognostic (7.01e-2)" "unprognostic (2.49e-1)" "unprognostic (4.84e-2)" "unprognostic (1.16e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-1)" "unprognostic (2.52e-1)" "unprognostic (4.61e-2)" 0.1 0.0 0.8 0.1 1.4 0.6 0.3 2.0 5.2 1.7 0.0 1.5 0.2 0.2 0.1 7.0 0.0 0.0 0.0 1.0 0.8 1.3 1.7 0.2 0.1 1.5 2.1 0.1 0.0 0.0 0.0 0.7 3.5 0.8 1.3 1.3 0.8 0.6 0.3 6.2 0.3 0.0 0.5 0.2 0.2 0.4 3.3 0.2 0.1 0.1 0.6 0.6 2.9 5.3 2.6 0.0 0.4 0.2 0.0 0.0 4.6 0.2 0.1 0.0 0.0 0.3 0.7 1.8 13.4 0.0 0.1 2.5 0.1 0.1 0.0 0.4 0.0 0.4 0.2 2.7 0.0 0.5 0.2 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.5 1.3 0.0 0.2 0.2 0.2 1.1 0.4 0.9 0.4 0.5 0.2 0.5 14.4 0.3 0.3 2.0 1.4 0.3 1.4 1.6 0.3 0.2 0.6 1.1 0.3 0.2 1.2 2.2 0.7 0.3 0.2 0.7 0.9 0.3 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.6 0.1 0.1 1.5 1.2 0.1 0.3 0.0 0.0 0.8 1.4 2.0 5.2 1.0 0.8 1.5 2.1 3.5 0.5 3.3 5.3 0.1 44.8 48.3 2.0 0.0 0.6 2.5 0.4 0.6 0.1 0.1 0.0 0.4 0.0 18.5 3.7 0.0 6.3 0.0 5.3 1.9 0.1 0.6 3.1 0.3 2.9 0.0 0.0 13.2 0.2 0.6 4.4 0.0 4.8 17.7 0.0 0.0 0.5 0.3 0.0 10.1 1.2 6.1 0.3 0.0 0.0 0.0 3.2 0.0 1.0 0.0 0.2 0.0 6.0 31.6 0.0 1.1 0.0 0.0 0.8 1.2 0.9 13.2 0.3 0.0 0.1 0.2 0.0 0.2 3.7 1.7 13.7 2.6 0.1 1.4 0.5 MAB21L4 "C2orf54, FLJ22671" ENSG00000172478 "Mab-21 like 4" Q08AI8 2 240886048-240896889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 262.6;vagina: 80.4" "Cell type enriched" "Detected in single" 7 "Cytotrophoblasts: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 45.9;HaCaT: 34.3;SK-BR-3: 117.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA052722 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA052722: " "unprognostic (5.86e-3)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.43e-2)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (1.70e-1)" "unprognostic (1.89e-2)" "unprognostic (2.83e-2)" "unprognostic (2.96e-1)" "unprognostic (2.08e-1)" "unprognostic (6.46e-2)" "unprognostic (1.55e-1)" "unprognostic (8.26e-2)" "unprognostic (2.05e-1)" 0.2 0.1 0.3 1.0 0.5 0.0 1.8 0.5 1.3 36.0 0.0 2.9 11.5 0.2 0.1 262.6 0.9 0.5 0.1 0.8 0.0 13.3 13.0 10.0 0.3 0.3 0.0 0.1 1.2 0.0 0.2 0.8 0.5 1.5 2.5 0.3 29.2 0.2 0.3 60.8 4.9 0.1 0.0 0.2 5.8 0.2 0.2 1.1 0.1 0.0 23.5 2.0 80.4 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 45.9 2.7 0.3 0.3 0.0 0.0 34.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 5.7 0.1 0.1 0.2 7.3 0.0 0.1 0.0 11.4 0.3 5.9 2.3 0.0 0.0 117.0 0.0 0.2 0.9 0.7 0.0 0.0 1.2 0.1 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.3 0.8 0.0 0.3 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 MACROH2A2 H2AFY2 ENSG00000099284 "MacroH2A.2 histone" Q9P0M6 10 70052544-70112282 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.1;Fibroblasts: 1.7;Hofbauer cells: 4.9;Syncytiotrophoblasts: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 12.6" "Group enriched" "Detected in many" 5 "dendritic cells: 12.6;monocytes: 5.4" "Cell line enhanced" "Detected in many" "AF22: 173.9;AN3-CA: 111.5;SCLC-21H: 137.0;SH-SY5Y: 132.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035865, HPA041189" Enhanced Supported Nucleoplasm No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA035865: AB_10672099, HPA041189: AB_2677357" "unprognostic (1.62e-2)" "unprognostic (9.62e-2)" "unprognostic (1.46e-2)" "unprognostic (1.46e-2)" "unprognostic (7.71e-3)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.17e-2)" "unprognostic (7.32e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (3.27e-2)" "unprognostic (4.58e-2)" "unprognostic (8.78e-2)" "unprognostic (4.66e-2)" 3.8 3.2 5.3 5.6 4.5 1.9 10.2 7.3 6.3 14.7 3.3 10.8 9.5 18.3 11.6 17.4 16.5 8.7 13.5 4.1 4.9 15.2 5.2 5.6 4.9 3.8 3.9 13.3 7.8 14.9 14.0 2.1 3.7 13.1 10.5 3.2 10.9 14.4 6.5 10.7 10.1 15.3 3.6 2.7 8.6 11.8 4.2 7.4 10.2 8.6 7.2 13.2 11.8 4.4 4.7 31.1 173.9 111.5 2.5 5.1 0.1 8.6 0.3 16.2 11.0 0.5 55.8 0.0 23.5 2.8 9.1 27.4 15.3 44.8 5.1 81.1 63.4 0.0 0.2 59.1 11.2 1.9 0.8 8.1 30.4 6.4 8.5 23.4 0.0 6.3 0.1 0.6 15.7 37.5 0.2 0.9 74.8 0.2 44.9 0.4 0.5 0.6 30.7 34.0 137.0 132.4 28.6 0.2 0.0 35.2 41.5 20.3 0.0 0.3 32.3 12.4 6.2 0.4 0.1 0.3 0.0 0.2 0.3 1.6 2.4 0.8 0.6 5.4 1.1 0.3 0.9 0.8 12.6 0.3 0.8 0.9 1.4 1.1 3.0 0.2 0.5 1.6 5.3 4.5 7.3 6.3 4.1 4.9 3.8 3.9 3.7 3.6 4.2 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 MAD2L1 "HSMAD2, MAD2" ENSG00000164109 "Mitotic arrest deficient 2 like 1" Q13257 4 120055623-120066858 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.9;lymphoid tissue: 5.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 81.8;Extravillous trophoblasts: 119.2;Spermatocytes: 127.8;Spermatogonia: 76.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003348 Uncertain Approved Nucleoplasm NA Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA003348: AB_10603014" "unprognostic (4.08e-3)" "unprognostic (7.31e-2)" "unprognostic (5.17e-3)" "unprognostic (1.10e-2)" "unprognostic (1.27e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (5.15e-5)" "prognostic unfavorable (2.17e-4)" "unprognostic (6.74e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "unprognostic (3.87e-3)" "prognostic unfavorable (3.07e-11)" "unprognostic (3.06e-2)" "unprognostic (4.05e-1)" "unprognostic (1.03e-1)" "unprognostic (9.70e-2)" 0.3 0.4 0.5 2.1 0.6 5.9 1.2 0.8 0.7 0.5 0.2 2.2 1.8 0.7 0.3 1.6 1.4 0.4 0.5 0.5 0.5 0.4 0.5 0.4 4.0 0.4 0.4 0.5 0.2 0.4 0.1 1.4 0.5 0.6 2.6 1.0 0.3 0.5 0.2 1.0 1.9 0.8 0.4 0.8 0.9 2.3 0.4 5.7 0.4 0.2 3.6 0.7 0.5 0.6 27.2 11.6 26.9 17.5 2.8 3.4 11.5 21.0 11.8 21.5 16.5 15.7 16.3 39.6 6.8 7.6 9.5 7.1 27.1 16.1 30.0 18.8 18.8 22.0 10.5 14.9 0.8 36.3 12.0 1.9 2.3 14.6 9.1 5.4 12.6 16.4 26.7 22.0 11.4 12.0 35.0 15.6 18.3 14.1 13.0 17.8 35.9 16.2 8.7 10.3 28.4 20.1 10.5 12.8 6.5 12.9 8.4 13.0 7.8 14.2 16.1 14.6 27.0 20.1 23.2 25.7 13.3 18.4 19.1 0.9 0.1 0.1 0.4 0.1 0.6 0.5 1.2 1.0 0.1 0.4 1.1 1.1 0.3 0.9 0.2 0.7 1.3 0.5 0.5 0.6 0.8 0.7 0.5 0.5 0.4 0.4 0.5 0.4 0.4 0.6 2.4 0.0 1.3 1.0 11.5 17.3 7.3 23.5 4.0 9.7 7.2 8.3 3.4 1.5 6.0 7.3 2.1 52.0 7.6 7.5 0.0 3.4 2.4 31.3 6.0 5.4 1.8 81.8 1.3 1.5 119.2 13.7 8.6 7.8 15.2 34.6 3.9 2.9 27.9 20.2 1.2 13.7 36.7 7.3 13.4 4.8 4.7 6.1 8.8 0.0 3.1 12.3 5.2 0.5 1.0 1.6 3.7 1.5 33.1 5.0 3.7 7.2 12.9 3.8 13.1 7.3 14.9 127.8 76.2 26.0 8.9 10.8 20.1 11.9 29.2 8.7 MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Mental retardation, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 407.6;Hofbauer cells: 273.6;Inhibitory neurons: 378.7;Kupffer cells: 394.7;Proximal enterocytes: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Group enriched" "Detected in some" 13 "Karpas-707: 207.0;RPMI-8226: 355.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB010296: AB_638562, HPA028289: AB_10602024" "unprognostic (6.76e-2)" "unprognostic (1.74e-2)" "unprognostic (6.45e-2)" "unprognostic (7.65e-2)" "unprognostic (7.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (2.33e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (4.54e-2)" "unprognostic (7.83e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" 27.8 15.4 14.6 20.7 14.5 4.0 17.3 10.3 13.5 35.0 14.2 11.4 70.3 23.5 6.0 22.6 20.1 16.7 6.8 13.7 13.0 48.2 25.7 18.8 30.9 19.0 22.6 39.2 3.2 50.8 5.3 36.1 17.6 18.4 10.7 4.7 11.8 15.4 49.6 57.8 83.0 17.8 18.7 26.0 13.0 10.0 28.7 17.9 23.1 19.8 23.9 17.7 30.5 29.8 0.0 0.0 22.4 0.0 0.8 0.0 0.5 2.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.0 0.8 0.7 0.4 0.0 7.2 8.3 0.0 0.0 0.2 1.0 0.1 14.3 0.1 6.4 0.0 0.2 0.0 0.0 0.3 2.4 207.0 1.5 0.1 0.2 0.4 13.5 0.0 0.0 0.1 6.2 355.1 0.0 1.9 0.5 0.3 0.9 0.2 0.6 8.7 0.2 0.0 4.5 0.0 6.9 0.5 0.9 0.0 0.0 0.0 0.9 0.0 1.4 38.1 0.3 0.0 1.1 1.1 8.6 0.0 3.2 2.7 0.1 0.0 0.2 0.5 0.0 0.9 0.3 0.0 4.7 0.6 14.6 14.5 10.3 13.5 13.7 13.0 19.0 22.6 17.6 18.7 28.7 29.8 40.2 9.6 14.6 24.8 10.4 88.3 3.7 30.1 51.2 9.7 8.5 33.1 8.2 57.2 7.7 3.7 0.0 1.7 71.5 18.2 11.7 1.7 1.1 8.1 114.1 42.7 3.0 8.4 5.1 0.8 3.0 73.0 12.8 6.6 22.1 73.0 407.6 63.7 273.6 0.0 378.7 8.9 16.2 394.7 57.9 9.0 149.8 127.2 44.4 122.7 2.7 78.1 40.2 67.3 20.0 4.0 9.9 115.1 48.1 33.9 288.9 146.6 3.0 2.7 13.1 42.7 40.0 1.1 2.0 107.4 141.2 4.2 122.2 28.0 10.1 5.4 MAGEA11 "CT1.11, MAGE-11, MAGE11, MAGEA-11, MGC10511" ENSG00000185247 "MAGE family member A11" P43364 X 149688228-149717268 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "epididymis: 21.0" "Group enriched" "Detected in some" 5 "Spermatocytes: 29.4;Spermatogonia: 30.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-2 OS: 23.8" HPA052687 Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "HPA052687: AB_2681915" "unprognostic (4.06e-3)" "unprognostic (2.05e-1)" "unprognostic (7.21e-2)" "unprognostic (1.09e-2)" "unprognostic (9.64e-2)" "unprognostic (1.32e-1)" "unprognostic (6.13e-2)" "unprognostic (1.16e-1)" "unprognostic (6.67e-4)" "unprognostic (1.14e-1)" "unprognostic (1.33e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 23.8 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 30.9 0.0 0.0 5.9 0.0 0.0 0.0 0.0 MAGED2 "11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386" ENSG00000102316 "MAGE family member D2" Q9UNF1 X 54807599-54816015 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Bartter syndrome, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Granulosa cells: 1684.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031572, HPA031573" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No 120000 "Cluster 44: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nucleoli, Cytosol" "HPA031572: AB_10599819, HPA031573: AB_10602181" "unprognostic (1.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.32e-1)" "unprognostic (1.69e-3)" "unprognostic (4.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.41e-3)" "unprognostic (1.39e-1)" "unprognostic (2.97e-1)" "prognostic favorable (2.88e-4)" "prognostic favorable (2.82e-4)" "unprognostic (6.34e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" "unprognostic (3.58e-1)" 81.6 125.1 102.3 52.8 97.8 31.8 162.6 104.9 112.2 174.5 111.7 106.8 54.3 134.3 101.9 67.4 149.0 94.3 142.2 95.5 121.9 141.0 57.5 85.9 48.0 125.4 118.4 255.9 75.5 148.0 195.3 177.1 128.8 208.8 53.5 74.4 103.3 169.9 88.9 60.5 62.5 140.6 108.5 60.8 77.6 63.1 110.1 68.8 149.2 91.4 46.2 111.7 95.7 108.9 34.0 61.4 373.7 111.0 171.6 229.5 66.8 137.9 243.7 106.4 187.5 62.3 84.4 47.1 361.2 279.0 88.5 45.2 106.5 104.2 76.1 84.5 87.0 100.0 68.6 122.1 145.5 25.4 71.8 310.4 43.0 109.3 55.5 223.6 209.9 55.2 24.5 55.7 207.6 94.0 57.0 41.9 134.7 59.1 72.4 37.4 132.9 68.2 148.5 25.3 56.6 149.5 54.7 62.4 330.6 437.5 263.1 42.9 185.0 90.4 141.3 135.9 39.5 35.7 32.7 34.5 132.0 66.7 477.6 178.5 31.9 132.1 119.1 80.0 91.7 59.2 98.1 112.1 41.1 63.9 97.3 112.0 11.8 108.6 140.8 25.8 108.9 127.4 102.3 97.8 104.9 112.2 95.5 121.9 125.4 118.4 128.8 108.5 110.1 108.9 77.9 44.8 42.8 17.6 37.4 42.4 96.4 198.6 43.3 69.8 123.3 97.8 60.5 44.3 175.4 77.3 29.2 231.5 36.9 11.9 246.5 107.4 3.4 42.4 96.8 116.4 58.3 10.3 12.9 53.7 133.7 151.7 20.9 57.1 102.1 1684.0 79.9 16.2 69.1 138.0 20.3 48.8 173.0 19.5 47.4 17.4 233.3 41.1 158.3 21.5 42.1 175.9 44.3 17.6 20.4 47.9 33.7 320.4 46.7 75.2 25.5 149.3 119.9 66.0 157.8 77.7 236.3 12.8 13.7 15.3 34.9 169.2 51.4 58.6 25.3 76.6 MAL "MVP17, VIP17" ENSG00000172005 "Mal, T cell differentiation protein" P21145 2 95025677-95053992 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2817.9;vagina: 863.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 373.3;Distal tubular cells: 236.7;Muller glia cells: 91.5;Oligodendrocytes: 168.1;Skeletal myocytes: 82.3;Squamous epithelial cells: 90.9" "Cancer enhanced" "Detected in many" "renal cancer: 101.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 217.6;naive CD4 T-cell: 293.3;naive CD8 T-cell: 138.1;T-reg: 233.6" "Lineage enriched" "Detected in many" 38 "T-cells: 293.3" "Cell line enhanced" "Detected in some" "HDLM-2: 516.4;MOLT-4: 722.0;RPMI-8226: 256.7;RPTEC TERT1: 2531.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065691 Approved "Golgi apparatus,Centrosome" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" Centrosome "HPA065691: AB_2685533" "unprognostic (1.57e-3)" "unprognostic (2.64e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (5.18e-6)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (5.13e-2)" "unprognostic (2.35e-2)" "unprognostic (1.06e-1)" "unprognostic (3.59e-1)" "unprognostic (4.61e-2)" "unprognostic (3.89e-2)" "prognostic favorable (3.96e-9)" "unprognostic (1.91e-1)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.57e-1)" 5.3 1.8 251.3 10.8 333.9 12.7 4.4 264.8 400.2 450.7 177.4 50.8 2.2 2.6 8.3 2817.9 8.9 2.9 17.9 260.8 256.7 400.4 1.7 25.3 25.1 281.3 282.1 3.2 3.0 0.4 3.9 3.4 272.9 21.8 6.3 10.1 544.0 11.1 2.8 12.6 17.0 2.4 264.0 9.4 52.7 1.1 303.2 261.2 21.3 4.3 352.8 15.0 863.2 449.3 51.3 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 12.0 0.0 0.3 2.4 0.2 0.0 0.5 516.4 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.4 2.4 0.4 0.1 0.1 0.0 722.0 0.2 0.2 0.0 0.0 0.7 0.0 256.7 2531.4 65.3 0.6 0.0 0.1 9.4 1.6 2.1 0.3 0.9 0.8 0.0 0.2 0.1 0.5 0.4 0.3 0.3 0.3 0.4 0.1 0.7 0.6 0.1 4.7 0.3 2.1 3.1 217.6 38.4 0.5 3.5 293.3 138.1 2.6 7.7 0.6 1.2 233.6 71.0 251.3 333.9 264.8 400.2 260.8 256.7 281.3 282.1 272.9 264.0 303.2 449.3 0.9 0.0 0.0 12.1 3.1 1.1 0.2 0.0 1.8 1.5 1.2 0.9 11.3 0.0 1.3 373.3 4.2 0.2 0.9 0.0 236.7 0.1 5.3 4.3 0.6 0.5 0.0 46.1 0.5 0.0 0.0 4.7 24.5 8.2 1.3 3.2 2.5 0.0 0.1 5.0 0.5 0.0 14.2 0.0 1.3 19.5 0.9 1.0 17.8 1.9 2.5 91.5 4.1 6.6 168.1 0.1 0.0 0.0 8.9 0.2 0.0 3.2 0.0 2.7 6.6 82.3 5.3 0.0 0.6 90.9 1.0 0.3 35.8 0.0 0.1 0.8 MAL2 ENSG00000147676 "Mal, T cell differentiation protein 2" Q969L2 8 119165034-119245673 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 259.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 389.9;Distal enterocytes: 433.3;Pancreatic endocrine cells: 329.8;Suprabasal keratinocytes: 455.8;Urothelial cells: 594.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1042.5;HaCaT: 451.8;OE19: 1132.4;RPTEC TERT1: 385.4;SK-BR-3: 1439.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043831 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA043831: " "prognostic unfavorable (4.57e-6)" "unprognostic (3.12e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (2.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.03e-2)" "unprognostic (7.20e-2)" "unprognostic (5.86e-2)" "unprognostic (2.00e-3)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.09e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.48e-2)" "unprognostic (1.34e-1)" "unprognostic (3.33e-1)" "unprognostic (9.27e-3)" 14.1 1.8 8.5 10.6 13.4 0.0 65.6 15.3 28.0 41.9 0.0 102.9 64.3 6.7 14.2 259.2 54.4 33.1 2.1 22.2 17.0 85.7 47.0 81.6 1.3 0.0 4.2 0.5 37.4 43.5 35.8 12.0 0.0 26.9 94.2 2.6 62.6 41.2 0.4 121.0 53.0 2.6 0.0 0.4 137.6 12.5 8.3 4.3 147.5 0.1 56.0 69.0 102.6 3.4 1042.5 0.0 1.0 0.3 0.2 0.0 92.9 0.1 2.3 1.2 1.6 87.7 329.0 0.3 56.2 0.0 0.4 451.8 0.8 32.9 0.5 0.9 2.6 0.0 13.8 86.1 0.3 0.6 0.3 0.0 225.5 0.0 34.3 1.7 0.3 0.0 0.2 0.5 0.0 244.9 0.8 0.3 8.2 1132.4 309.2 0.6 0.0 0.7 385.4 257.4 56.7 0.3 17.8 1439.4 2.7 6.8 191.4 3.0 0.0 0.6 3.1 1.3 1.9 5.5 0.8 1.0 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 13.4 15.3 28.0 22.2 17.0 0.0 4.2 0.0 0.0 8.3 3.4 0.5 112.2 130.8 4.2 2.7 114.7 79.9 59.3 19.9 1.5 118.9 50.7 1.6 90.1 119.7 389.9 0.0 25.0 0.4 433.3 109.5 206.0 0.5 71.8 10.3 3.7 41.9 0.0 62.4 178.6 23.5 4.7 149.9 139.4 14.7 0.0 3.6 44.9 2.9 5.0 9.8 145.9 71.2 0.3 14.3 2.2 0.6 2.3 16.0 3.7 3.6 1.0 0.0 3.5 3.6 329.8 252.9 0.0 1.2 285.4 70.2 19.9 107.5 1.0 0.0 0.0 7.0 1.9 9.7 268.8 455.8 9.3 2.8 0.0 122.5 594.5 MALL BENE ENSG00000144063 "Mal, T cell differentiation protein like" Q13021 2 110083870-110116022 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 368.5;intestine: 235.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 857.8;Ductal cells: 299.2;Pancreatic endocrine cells: 354.9;Paneth cells: 374.4;Proximal enterocytes: 742.2;Urothelial cells: 426.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 8.4;neutrophil: 2.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "A-431: 267.4;A549: 269.9;CAPAN-2: 347.7;fHDF/TERT166: 380.9;HaCaT: 276.4;PC-3: 158.3" "Not detected" "Not detected" HPA051410 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA051410: AB_2681474" "unprognostic (5.17e-1)" "unprognostic (4.15e-2)" "unprognostic (2.92e-1)" "unprognostic (3.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (4.46e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (2.37e-1)" "unprognostic (7.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.84e-1)" "unprognostic (2.80e-1)" "unprognostic (6.50e-3)" 17.2 2.9 3.9 17.2 3.7 2.4 13.4 3.6 3.8 58.2 4.7 114.1 235.4 6.3 5.7 368.5 8.4 20.3 18.6 3.6 4.9 7.0 3.1 79.9 6.1 4.1 4.2 2.0 4.4 97.8 2.6 9.3 4.6 18.9 95.1 0.4 40.8 4.2 6.3 43.7 218.8 14.4 4.9 5.0 9.2 9.7 6.9 3.1 28.6 10.8 55.0 98.6 148.1 4.2 267.4 269.9 0.2 0.9 0.1 0.1 0.8 48.5 2.1 0.2 0.2 44.3 347.7 0.6 127.6 380.9 0.1 276.4 0.0 12.6 0.1 0.7 0.2 1.8 7.3 0.1 1.9 0.1 0.6 4.8 13.9 1.2 0.0 0.0 111.9 0.0 0.1 0.4 0.0 10.0 0.0 1.0 0.2 117.8 158.3 0.1 0.1 1.2 30.4 15.3 0.7 0.2 0.2 9.3 0.7 0.4 0.3 1.4 130.9 0.4 0.9 0.7 0.8 0.3 0.4 31.7 0.4 0.4 0.2 8.4 0.4 0.6 0.2 0.2 0.2 0.5 0.5 0.4 0.2 0.5 0.3 0.5 2.5 1.2 0.1 0.4 0.3 0.3 3.9 3.7 3.6 3.8 3.6 4.9 4.1 4.2 4.6 4.9 6.9 4.2 45.1 41.7 185.9 0.3 2.0 16.4 107.2 38.6 3.4 0.0 10.9 6.1 3.2 2.8 64.6 1.8 0.0 0.3 0.4 857.8 0.0 299.2 26.3 3.2 1.8 50.6 17.5 0.0 0.8 66.1 0.1 8.2 2.6 7.6 7.0 0.4 33.9 0.5 8.2 0.0 0.1 51.2 30.5 0.9 3.8 9.7 2.5 2.9 14.2 2.8 1.0 0.1 0.0 0.0 0.0 354.9 374.4 1.2 0.0 187.4 742.2 14.6 19.4 0.1 0.0 1.1 5.6 27.2 1.3 57.9 13.2 0.5 2.4 0.6 97.4 426.0 MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: AB_2680389" "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" 7.1 2.5 2.9 11.2 2.8 10.5 6.3 4.8 3.6 7.7 4.2 5.1 3.6 5.4 4.2 12.5 5.1 5.8 5.4 3.1 4.1 6.7 6.9 7.3 21.1 3.2 2.6 5.3 4.0 5.3 4.7 4.0 3.0 11.5 5.5 8.7 5.8 3.8 8.3 9.4 7.7 4.2 3.0 11.5 4.6 8.2 4.1 15.6 5.3 2.8 23.1 7.1 9.6 3.6 11.4 16.0 16.8 5.2 3.1 6.7 9.2 19.7 12.1 15.7 12.6 13.8 13.5 27.0 10.3 24.0 11.1 12.0 10.8 7.6 20.8 17.0 6.8 9.7 9.0 21.8 4.0 20.1 11.4 4.0 12.2 11.8 10.4 6.6 3.4 7.7 15.3 42.3 9.6 3.3 4.7 9.7 6.3 4.1 7.1 14.8 11.5 19.7 88.9 2.8 2.5 4.5 11.7 6.0 9.3 12.0 5.1 12.2 5.7 22.6 9.1 7.1 20.8 38.5 54.4 16.3 10.6 15.6 9.9 0.3 0.5 0.2 0.7 0.7 0.6 1.1 1.4 0.8 0.7 2.1 1.0 0.8 0.3 0.5 0.5 1.3 0.8 0.4 2.9 2.8 4.8 3.6 3.1 4.1 3.2 2.6 3.0 3.0 4.1 3.6 35.0 22.4 19.2 24.2 67.8 33.0 32.3 4.8 26.2 14.7 13.6 11.0 14.4 10.0 7.0 11.0 85.5 6.2 53.2 11.1 3.9 16.6 12.7 10.4 17.5 31.1 6.7 0.8 61.3 8.5 6.0 15.7 13.7 24.7 31.7 28.1 10.4 11.1 11.8 55.5 42.9 8.6 8.2 21.0 96.5 8.0 10.2 55.9 12.4 34.7 79.5 26.2 20.6 52.3 11.9 16.2 21.9 7.2 42.2 46.6 8.0 30.7 5.8 18.1 19.7 16.1 12.9 40.1 35.6 25.4 24.7 9.0 55.2 5.7 10.7 38.1 MAML3 "CAGH3, GDN, KIAA1816, MAM2, TNRC3" ENSG00000196782 "Mastermind like transcriptional coactivator 3" Q96JK9 4 139716753-140154184 "Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 125.6;Microglial cells: 355.1;Oligodendrocytes: 150.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 16.8" "Immune cell enhanced" "Detected in many" "basophil: 12.2" "Group enriched" "Detected in many" 5 "granulocytes: 12.2;NK-cells: 3.4" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 15.0;SCLC-21H: 15.7;SH-SY5Y: 23.9;WM-115: 20.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037717 Approved Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA037717: AB_10794323" "unprognostic (1.83e-1)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (7.83e-3)" "unprognostic (4.73e-2)" "unprognostic (2.63e-1)" "unprognostic (3.36e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (3.89e-1)" "unprognostic (5.52e-3)" "unprognostic (1.73e-1)" "prognostic favorable (7.60e-5)" "unprognostic (3.38e-1)" "unprognostic (1.20e-1)" "unprognostic (7.22e-2)" "unprognostic (2.88e-1)" 3.3 3.4 1.5 2.4 0.9 3.2 3.4 16.8 2.1 5.0 0.1 3.8 4.8 6.7 5.3 5.9 5.5 4.1 2.0 2.2 2.8 2.0 2.6 3.8 2.6 3.4 2.3 8.6 6.8 3.3 4.5 5.0 3.4 4.9 3.9 1.7 5.9 4.5 1.7 7.8 4.5 6.0 2.4 3.3 3.4 3.0 2.2 6.0 4.3 2.1 2.3 3.6 5.1 2.2 0.5 8.1 5.4 2.7 2.1 4.4 4.9 1.0 4.4 0.5 0.3 3.2 2.2 1.8 0.4 0.8 0.3 0.1 2.1 1.8 0.3 0.0 1.2 5.9 1.9 0.3 0.4 2.8 8.7 4.3 1.5 0.1 0.9 3.3 15.0 0.1 1.6 0.0 0.3 0.9 0.5 1.2 1.4 3.6 3.5 3.5 0.5 3.6 2.5 11.2 15.7 23.9 0.0 4.2 5.5 4.2 2.3 0.8 13.1 0.6 1.3 0.1 1.7 2.9 3.5 0.1 0.8 9.2 20.2 12.2 1.5 2.9 0.0 1.1 0.1 0.0 0.0 0.0 1.5 0.4 0.4 0.4 3.6 3.4 0.9 1.2 0.0 1.2 1.5 0.9 16.8 2.1 2.2 2.8 3.4 2.3 3.4 2.4 2.2 2.2 21.2 3.2 11.5 39.5 3.1 8.0 8.1 4.2 7.4 4.6 12.6 9.3 3.0 11.5 8.7 5.5 18.8 5.8 3.9 13.6 5.9 5.1 3.6 12.6 9.4 11.7 14.9 9.4 60.2 5.1 7.3 5.3 8.6 19.9 19.6 34.4 13.2 17.5 7.5 11.8 125.6 12.1 2.0 22.6 13.3 9.0 4.1 19.6 3.6 355.1 18.3 3.1 1.0 7.5 150.8 3.0 14.0 3.8 2.1 5.7 8.2 6.1 7.2 3.7 0.0 2.9 13.7 0.5 2.2 19.0 13.5 8.2 5.3 8.5 11.0 8.9 MANEAL FLJ31434 ENSG00000185090 "Mannosidase endo-alpha like" Q5VSG8 1 37793847-37801137 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 16.5;Enteroendocrine cells: 30.5;Horizontal cells: 26.9;Inhibitory neurons: 12.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063423 Approved "Golgi apparatus" "Intracellular and membrane" NA NA 47000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" "HPA063423: AB_2685011" "unprognostic (8.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (7.92e-2)" "prognostic favorable (5.28e-4)" "prognostic unfavorable (3.32e-4)" "unprognostic (3.02e-1)" "unprognostic (1.03e-2)" "unprognostic (7.67e-2)" "unprognostic (6.27e-3)" "unprognostic (1.08e-1)" "unprognostic (1.17e-3)" "unprognostic (8.29e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (2.26e-1)" 1.1 7.1 16.3 2.1 16.7 0.2 5.0 12.3 18.2 2.9 4.6 6.1 3.5 1.9 6.5 4.7 2.8 1.3 1.3 16.6 21.4 3.6 9.1 3.0 1.2 16.1 17.0 1.2 10.1 5.9 19.3 0.9 20.0 4.2 6.3 13.3 3.6 2.7 4.0 4.1 3.5 2.3 11.9 1.9 4.6 2.7 20.1 1.3 5.6 2.6 1.9 2.3 2.4 13.6 24.0 30.1 5.4 57.1 7.3 2.7 51.7 4.4 26.0 22.1 9.6 50.3 55.0 40.0 18.8 3.1 26.1 5.4 11.1 5.9 7.9 47.5 23.7 29.4 25.5 41.0 0.5 42.3 23.4 0.9 30.6 1.2 1.1 30.7 0.6 7.1 17.5 30.4 3.5 47.8 11.9 0.1 18.1 57.0 31.8 18.2 39.0 46.2 13.1 62.8 139.8 42.4 63.0 2.0 23.6 1.0 27.3 4.4 3.5 31.0 19.0 30.2 41.0 43.6 45.0 13.1 5.1 13.7 23.2 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 16.3 16.7 12.3 18.2 16.6 21.4 16.1 17.0 20.0 11.9 20.1 13.6 1.1 3.2 2.7 0.3 1.0 0.5 1.1 0.3 2.2 16.5 4.3 4.3 1.1 1.5 0.6 3.7 4.2 0.2 1.1 2.3 0.0 1.6 0.2 1.1 0.7 0.8 30.5 0.0 9.0 6.0 2.0 1.0 1.1 2.5 0.0 1.8 0.0 5.0 0.9 26.9 12.1 3.7 0.0 0.8 0.4 0.0 0.3 0.5 3.6 3.7 0.0 5.0 0.0 9.5 2.7 2.4 2.3 0.0 2.4 1.7 1.1 0.4 0.2 9.5 0.0 0.7 0.4 0.0 1.5 1.5 0.0 0.1 0.7 0.5 4.1 1.3 MAP1A MAP1L ENSG00000166963 "Microtubule associated protein 1A" P78559 15 43510958-43531620 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 325.5" "Cell type enhanced" "Detected in many" "dendritic cells: 90.9;Horizontal cells: 299.5;Peritubular cells: 76.3" "Cancer enhanced" "Detected in many" "glioma: 18.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 61 "plasmacytoid DC: 10.5" "Lineage enriched" "Detected in single" 61 "dendritic cells: 10.5" "Cell line enhanced" "Detected in many" "ASC diff: 60.7;BJ hTERT+: 61.8;fHDF/TERT166: 94.0;hTEC/SVTERT24-B: 58.1;U-87 MG: 121.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039063, HPA039064, HPA066488" Enhanced Approved Cytosol No No 55000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA039063: AB_2676327, HPA039064: AB_10673302, HPA066488: AB_2685676" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (3.29e-2)" "unprognostic (1.86e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-2)" "unprognostic (5.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.65e-2)" "unprognostic (1.13e-3)" "unprognostic (8.36e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (6.59e-5)" "unprognostic (5.83e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (1.09e-5)" "prognostic unfavorable (1.66e-5)" 7.2 6.0 65.3 3.8 78.6 0.9 4.4 39.5 325.5 8.0 0.0 16.5 1.2 8.2 2.4 3.0 7.2 4.2 15.5 92.8 37.5 1.2 0.2 2.2 1.0 201.4 41.4 5.0 1.0 2.0 11.7 2.7 186.0 4.8 3.5 21.7 2.5 7.5 4.5 3.2 4.0 13.1 22.5 0.9 4.3 3.8 85.8 24.0 4.1 5.1 0.9 11.9 4.5 156.7 0.3 2.5 11.1 6.4 60.7 41.5 0.1 36.3 61.8 10.5 10.1 4.4 0.1 0.2 15.3 94.0 3.3 0.5 15.0 0.1 6.1 5.5 1.4 14.2 3.5 0.3 5.8 0.4 5.8 31.3 0.1 58.1 0.3 15.8 8.0 41.3 24.0 0.3 42.8 0.5 26.6 0.8 8.1 0.0 1.0 7.2 32.1 0.1 0.2 0.1 34.8 10.6 1.2 0.1 0.3 14.6 2.3 0.6 1.5 33.7 11.3 11.3 0.5 0.0 1.6 5.0 121.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.1 0.1 65.3 78.6 39.5 325.5 92.8 37.5 201.4 41.4 186.0 22.5 85.8 156.7 6.7 3.2 1.1 11.8 2.2 5.5 1.4 1.4 2.8 43.4 1.7 3.6 55.1 0.0 7.9 3.7 25.0 0.3 90.9 1.0 0.0 0.4 13.1 33.2 19.5 5.7 11.4 3.0 34.4 0.0 0.6 46.9 2.6 1.0 7.0 16.7 4.2 0.0 2.4 299.5 45.1 1.7 10.2 0.3 7.4 5.6 51.0 9.4 8.8 12.2 0.7 16.7 0.0 9.5 51.4 0.7 0.0 76.3 1.1 0.5 0.0 0.5 63.6 27.2 32.9 45.7 48.2 10.6 25.6 1.1 4.1 1.1 5.6 3.1 1.4 0.5 MAP1LC3A "ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3" ENSG00000101460 "Microtubule associated protein 1 light chain 3 alpha" Q9H492 20 34546854-34560345 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 674.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 85.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 85.4" "Cell line enhanced" "Detected in many" "HHSteC: 57.5;HSkMC: 71.2;SK-BR-3: 62.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007649, CAB037174, HPA042824, HPA052474, HPA052484" Enhanced Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB037174: AB_1079382, HPA007649: AB_1853943, HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846" "unprognostic (6.10e-3)" "unprognostic (8.03e-2)" "unprognostic (1.02e-1)" "unprognostic (1.99e-2)" "unprognostic (4.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.55e-1)" "unprognostic (1.79e-1)" "unprognostic (4.78e-2)" "unprognostic (1.98e-1)" "prognostic favorable (5.31e-5)" "unprognostic (2.82e-2)" "unprognostic (1.59e-3)" "unprognostic (3.84e-1)" "unprognostic (1.35e-1)" "unprognostic (7.90e-2)" "unprognostic (2.76e-1)" 53.0 26.6 120.8 13.7 122.1 16.4 40.6 114.4 177.2 49.6 69.7 56.3 30.6 44.9 17.8 22.6 41.7 23.9 81.7 123.7 148.4 54.2 53.2 39.4 28.1 137.1 135.6 38.3 24.8 23.7 84.8 12.4 155.9 46.6 19.7 31.6 31.0 20.3 54.7 64.8 44.9 19.1 101.2 22.0 36.6 52.8 116.2 6.9 52.9 34.1 30.4 39.1 43.5 123.3 0.0 7.0 4.2 0.0 28.4 37.3 0.2 26.1 21.9 16.3 14.9 0.1 0.5 0.0 0.3 21.3 39.5 4.8 0.1 8.1 3.2 6.2 2.0 0.1 17.2 0.0 57.5 0.0 14.0 71.2 1.4 11.4 4.9 0.1 13.5 0.0 0.0 0.1 17.4 0.0 0.2 0.5 1.6 5.3 5.2 0.0 0.0 0.0 0.0 0.0 41.4 31.9 29.6 62.2 0.0 16.3 0.3 22.7 20.5 45.2 0.4 9.8 11.2 0.0 6.5 0.0 29.4 0.0 16.1 4.0 3.2 11.0 5.1 4.8 3.7 9.4 5.5 5.4 1.0 6.0 1.7 3.4 85.4 3.3 1.7 4.5 12.1 2.9 120.8 122.1 114.4 177.2 123.7 148.4 137.1 135.6 155.9 101.2 116.2 123.3 107.4 0.0 6.6 19.2 18.3 57.7 123.0 50.5 12.5 127.2 41.9 57.8 25.4 41.5 27.1 46.0 85.5 25.7 26.1 67.3 113.5 42.0 137.3 98.4 78.4 64.4 165.1 3.6 48.4 23.5 15.8 75.4 34.1 90.6 18.4 90.8 75.7 44.6 37.9 70.7 58.8 70.5 136.3 16.1 47.1 674.0 95.1 17.5 62.2 14.0 21.0 98.7 7.2 12.5 54.6 44.7 82.5 108.7 10.1 146.3 149.4 120.0 40.7 127.7 138.1 77.7 119.3 53.0 21.6 5.8 51.4 211.8 26.4 79.8 76.7 98.1 MAP2K6 "MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3" ENSG00000108984 "Mitogen-activated protein kinase kinase 6" P52564 17 69414697-69553865 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 40.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 53.9;Glandular and luminal cells: 82.7;Oligodendrocytes: 52.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 8.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 22.0;neutrophil: 45.9;plasmacytoid DC: 78.3" "Group enriched" "Detected in all" 9 "dendritic cells: 78.3;granulocytes: 45.9;monocytes: 22.0" "Cell line enhanced" "Detected in many" "A549: 40.0;AN3-CA: 21.4;HUVEC TERT2: 28.4;MOLT-4: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007744, HPA031134" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "CAB007744: AB_562318, HPA031134: AB_10603016" "prognostic favorable (2.27e-6)" "unprognostic (2.24e-1)" "unprognostic (8.46e-2)" "unprognostic (4.10e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "unprognostic (7.61e-3)" "unprognostic (9.52e-2)" "unprognostic (3.67e-1)" "unprognostic (4.09e-3)" "prognostic favorable (7.52e-4)" "unprognostic (3.61e-2)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (9.43e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-2)" 5.2 1.3 4.2 8.4 4.0 15.9 20.4 11.6 4.0 27.0 7.6 30.7 10.3 6.1 3.2 3.1 4.5 7.2 1.4 2.7 6.2 5.5 12.2 1.8 8.0 5.4 3.8 3.1 8.3 0.3 1.6 1.6 3.9 3.3 31.7 5.8 2.5 3.1 40.5 2.0 10.8 3.3 4.4 4.0 7.4 1.3 5.7 11.5 3.3 21.1 5.9 3.3 1.2 7.7 0.1 40.0 17.6 21.4 7.4 4.0 2.5 0.3 5.8 1.6 2.4 1.2 1.7 1.1 14.2 0.8 1.3 1.9 6.1 0.8 0.5 1.3 3.2 0.1 10.3 11.4 7.4 1.7 1.3 19.0 0.5 0.3 0.0 1.4 28.4 5.3 0.1 2.5 0.0 0.3 21.6 0.7 12.5 0.9 7.3 7.7 1.8 0.5 7.8 5.4 7.8 11.8 1.7 1.3 3.9 9.3 5.4 2.3 5.1 1.9 2.3 1.6 0.5 1.7 2.2 0.5 1.6 2.5 1.5 2.5 22.0 4.0 2.8 2.6 5.0 4.1 3.1 3.5 7.1 5.2 3.6 3.4 45.9 4.7 1.1 78.3 5.0 6.2 4.2 4.0 11.6 4.0 2.7 6.2 5.4 3.8 3.9 4.4 5.7 7.7 11.2 3.2 6.7 27.7 7.7 2.7 4.1 0.8 8.6 5.2 14.3 29.1 1.3 5.7 3.6 0.0 2.1 9.7 29.2 42.3 23.5 1.9 10.2 53.9 11.5 7.9 45.6 5.0 26.0 4.1 6.6 5.0 9.2 82.7 1.3 13.4 4.2 2.5 6.2 3.3 22.4 22.9 0.0 6.8 7.4 2.9 4.4 6.9 3.6 24.4 9.6 31.8 10.3 32.6 52.5 1.1 16.7 3.8 10.7 1.3 14.5 1.5 4.2 4.2 0.0 3.9 5.7 0.1 1.8 4.8 4.3 0.8 13.3 1.4 30.6 2.8 MAP3K1 "MAPKKK1, MEKK, MEKK1" ENSG00000095015 "Mitogen-activated protein kinase kinase kinase 1" Q13233 5 56815549-56896152 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 210.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SH-SY5Y: 52.5;THP-1: 51.0" "Region enriched" "Detected in all" 6 "olfactory bulb: 18.2" "Low region specificity" "Detected in all" "CAB004500, HPA046509" Approved Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 57: B-cells - Immune response" Cytosol "CAB004500: AB_627926, HPA046509: AB_2679678" "unprognostic (1.77e-1)" "unprognostic (1.71e-2)" "unprognostic (4.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.48e-2)" "unprognostic (5.39e-3)" "unprognostic (5.20e-3)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.97e-3)" "unprognostic (2.18e-2)" "unprognostic (1.58e-1)" "unprognostic (9.92e-3)" "unprognostic (1.11e-1)" 5.5 3.8 3.0 13.3 2.6 24.0 20.1 4.0 2.1 7.0 6.2 5.4 6.3 7.5 6.6 10.0 9.7 5.7 3.7 2.1 2.7 9.9 6.0 7.5 18.1 3.9 3.2 7.2 9.8 7.1 1.3 11.4 3.7 5.4 6.3 26.9 18.5 8.3 1.7 19.7 6.5 5.7 3.8 20.5 8.1 8.3 3.5 9.9 16.2 4.4 24.0 6.7 6.4 3.9 13.3 7.9 12.1 8.1 1.9 1.5 20.3 2.5 3.3 7.6 10.6 37.1 9.7 11.9 0.9 3.0 6.5 6.7 10.1 4.6 10.5 4.0 4.4 6.6 3.4 17.5 4.7 10.6 17.6 1.9 4.8 2.4 3.8 2.1 3.3 4.0 5.8 20.7 2.0 5.8 7.4 14.2 5.6 6.8 1.0 11.5 8.6 41.1 13.2 13.6 5.1 52.5 7.6 9.5 21.5 10.7 26.0 51.0 9.8 0.7 6.4 2.9 4.7 15.0 8.2 22.1 1.2 6.1 13.2 6.3 3.1 0.7 0.8 4.5 0.7 4.0 2.4 1.1 1.8 3.3 1.5 0.5 1.7 1.7 4.9 1.0 3.8 1.7 3.0 2.6 4.0 2.1 2.1 2.7 3.9 3.2 3.7 3.8 3.5 3.9 20.8 6.4 9.8 17.9 102.5 52.4 15.1 17.1 43.9 14.9 73.2 30.6 3.5 48.6 15.9 36.8 47.9 15.1 31.9 7.3 7.9 18.9 2.0 25.0 20.6 24.0 10.2 14.5 11.7 14.8 8.6 10.7 14.3 43.7 7.6 20.0 21.8 15.0 32.3 28.6 31.8 11.4 6.1 76.0 48.4 3.6 5.3 66.5 37.4 69.3 99.1 11.6 9.2 210.1 12.5 12.9 7.7 1.9 41.5 14.8 10.6 20.7 11.0 38.5 6.6 9.3 11.9 8.6 17.9 69.1 54.7 6.7 31.6 15.4 9.7 12.0 MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7;retina: 9.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.6;Inhibitory neurons: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" 0.2 1.0 3.3 1.0 4.6 0.7 1.3 10.7 22.7 0.9 0.4 1.5 1.5 0.4 1.5 5.1 1.0 0.4 0.5 4.0 3.2 1.4 0.7 1.9 1.4 8.6 3.0 0.6 2.2 2.7 1.1 0.6 7.7 0.9 1.5 9.6 1.7 0.5 0.8 4.0 1.4 0.2 0.3 0.9 1.6 5.5 10.0 0.9 2.7 0.4 3.6 0.7 1.8 6.8 22.3 10.5 2.0 2.5 0.0 0.0 6.7 0.5 0.3 2.1 1.9 7.8 8.6 4.5 2.8 0.1 4.7 10.3 6.5 12.8 2.2 3.0 1.7 0.2 4.1 5.2 0.3 0.5 0.9 0.1 6.5 1.5 12.7 3.7 0.0 4.1 1.7 1.0 0.5 9.4 3.7 0.5 4.2 9.0 4.5 1.3 3.9 0.9 4.6 10.9 13.8 3.0 6.3 7.7 1.2 3.7 6.9 0.8 0.0 0.0 8.5 0.0 3.5 2.2 5.6 2.4 3.4 0.4 1.4 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.2 0.2 0.0 0.0 0.2 0.0 3.3 4.6 10.7 22.7 4.0 3.2 8.6 3.0 7.7 0.3 10.0 6.8 0.3 6.4 13.4 6.8 3.9 8.7 13.7 9.4 6.8 17.7 11.2 4.8 2.3 14.3 12.4 7.3 12.5 2.8 1.7 5.7 1.9 6.1 19.8 7.4 0.7 0.8 8.4 0.0 49.6 4.8 1.6 1.0 4.1 8.5 1.3 1.8 1.1 4.8 1.2 30.3 58.1 4.0 4.1 0.8 1.9 20.0 0.6 0.8 3.6 5.6 0.4 3.2 0.0 8.5 1.3 11.1 3.9 0.0 2.8 15.8 2.6 2.8 7.1 12.7 0.0 0.8 1.3 8.0 8.4 12.6 9.1 4.0 3.7 6.0 5.8 27.9 MAP6 "FLJ41346, KIAA1878, MAP6-N, STOP" ENSG00000171533 "Microtubule associated protein 6" Q96JE9 11 75586918-75669038 "Predicted intracellular proteins" Transport Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 76.8;retina: 96.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 81.2;Cone photoreceptor cells: 158.4;Excitatory neurons: 75.8;Horizontal cells: 50.5;Inhibitory neurons: 43.3;Late spermatids: 41.9" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 37.8;CACO-2: 38.1;HDLM-2: 21.5;SCLC-21H: 62.4;SH-SY5Y: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015442, CAB022600, HPA039061, HPA039062" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "CAB015442: AB_2140997, CAB022600: , HPA039061: AB_2676325, HPA039062: AB_2676326" "unprognostic (3.04e-2)" "unprognostic (6.18e-2)" "unprognostic (3.15e-2)" "unprognostic (9.07e-2)" "unprognostic (7.54e-2)" "unprognostic (4.49e-2)" "unprognostic (8.29e-2)" "unprognostic (2.51e-2)" "unprognostic (5.99e-2)" "unprognostic (7.99e-2)" "prognostic favorable (3.41e-4)" "prognostic favorable (9.15e-4)" "unprognostic (2.43e-2)" "unprognostic (3.96e-3)" "unprognostic (8.09e-3)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" 4.8 19.0 68.3 2.0 68.0 0.0 3.5 50.7 70.6 10.6 64.4 23.0 1.7 18.1 21.0 4.2 40.7 6.4 8.6 67.7 71.5 17.0 1.2 7.8 0.7 70.2 64.6 8.0 3.6 22.0 76.8 1.5 70.8 17.8 3.5 96.1 3.6 21.1 1.0 8.1 4.8 13.1 52.9 2.4 10.7 18.6 68.5 0.8 7.9 1.3 0.5 7.1 8.4 59.7 0.2 0.7 37.8 0.1 0.1 0.0 0.0 3.8 0.2 0.3 0.0 38.1 0.1 0.6 1.4 6.3 1.3 0.0 3.4 0.5 0.0 21.5 0.5 0.0 0.0 0.0 1.0 0.0 0.0 2.1 0.5 0.1 0.2 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 5.9 0.0 2.9 0.0 0.0 0.1 0.1 0.5 62.4 31.7 4.6 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.0 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.3 68.0 50.7 70.6 67.7 71.5 70.2 64.6 70.8 52.9 68.5 59.7 1.2 3.2 3.7 25.8 0.1 0.8 1.7 0.7 0.0 81.2 0.8 1.8 8.4 1.5 3.1 11.0 158.4 0.2 0.2 0.0 1.9 0.1 27.7 28.2 4.6 1.6 13.1 0.0 75.8 0.2 0.0 2.9 0.0 0.8 0.0 0.8 2.2 0.3 0.1 50.5 43.3 0.0 6.1 0.0 1.1 41.9 7.5 0.3 5.4 1.9 0.0 18.7 0.0 13.0 13.3 0.2 0.0 18.4 0.1 1.4 0.0 1.2 25.4 10.2 0.0 1.9 5.7 23.5 4.3 0.1 0.4 0.0 0.3 0.1 0.0 0.4 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21759657-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 341.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069, CAB079930, CAB079932, CAB079933" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nuclear speckles" "CAB004229: AB_627547, CAB079930: , CAB079932: , CAB079933: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 31.1 33.1 64.8 35.9 84.4 41.2 29.8 37.3 80.9 31.4 32.9 36.1 25.8 29.6 30.1 43.0 29.0 28.9 42.2 91.3 46.4 42.1 34.2 38.5 36.8 29.1 45.1 29.2 38.1 51.7 12.0 33.1 35.9 32.8 36.2 30.3 28.9 32.7 38.1 45.0 29.5 39.1 43.8 40.5 33.9 43.7 60.1 44.4 46.1 41.9 41.9 35.5 18.9 43.2 78.7 48.0 60.5 37.2 75.9 76.7 25.9 84.7 77.5 73.2 72.0 43.8 40.8 45.8 41.3 112.7 67.5 74.6 73.9 67.9 97.8 180.4 72.1 78.9 43.0 67.7 73.5 113.2 80.5 56.9 60.1 89.4 81.6 58.0 101.7 45.4 341.9 50.5 97.5 36.6 72.0 38.5 24.4 104.5 46.8 79.4 149.6 13.2 55.5 62.9 50.0 28.6 91.5 64.2 57.2 60.4 42.4 47.1 90.1 61.5 79.6 71.9 54.2 47.1 59.4 65.8 60.0 60.0 68.4 1.4 4.9 7.2 15.9 6.0 4.9 2.3 3.6 6.0 4.1 2.6 3.5 6.1 16.5 9.3 6.9 4.0 3.4 4.0 64.8 84.4 37.3 80.9 91.3 46.4 29.1 45.1 35.9 43.8 60.1 43.2 36.8 48.1 35.8 97.6 44.0 60.2 28.4 25.1 28.5 25.5 32.5 24.5 41.5 42.9 31.2 51.5 54.2 21.8 151.7 74.4 19.6 28.5 49.0 33.5 40.3 39.9 59.6 63.8 109.2 39.2 23.2 38.4 52.0 45.0 92.8 28.8 52.1 63.5 53.2 28.6 91.2 42.2 26.4 89.0 77.1 14.7 32.6 74.9 40.9 68.4 75.0 35.8 143.2 82.4 75.1 45.3 35.2 44.4 37.0 43.8 32.8 46.0 32.2 22.4 32.9 44.6 37.3 74.1 53.4 44.9 61.8 19.2 91.4 43.3 38.6 38.8 MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 146.2;Late spermatids: 282.5;Proximal enterocytes: 178.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 63.8;RPMI-8226: 40.2;RT4: 47.0" "Low region specificity" "Detected in single" "Region enriched" "Detected in all" 14 "cerebellum: 37.5" "HPA007667, CAB025854" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nucleoli, Nucleoli rim, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favorable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" 8.7 55.9 3.1 8.8 3.0 9.4 14.2 0.5 4.4 18.6 0.0 44.6 30.9 3.4 11.5 102.4 7.6 7.5 2.5 2.9 2.2 17.3 6.7 23.8 7.9 0.6 0.0 5.4 47.7 38.9 33.3 5.6 0.2 16.7 24.4 2.7 49.5 15.5 1.2 74.1 40.1 1.9 0.1 16.1 24.1 40.0 4.2 6.9 18.9 1.0 12.4 12.2 39.3 2.7 31.4 0.3 0.7 0.5 2.4 11.2 4.3 3.3 0.4 0.3 0.8 22.3 28.4 7.0 2.0 2.5 4.6 24.4 0.3 63.8 0.7 20.0 7.9 0.2 1.2 22.8 4.0 0.4 2.2 9.2 25.9 4.3 1.0 4.5 4.1 1.2 0.6 9.4 0.9 12.7 0.4 2.6 0.4 30.9 0.4 21.0 0.5 40.2 11.6 47.0 30.5 0.7 2.5 0.5 0.2 1.3 33.0 4.1 6.3 2.4 0.4 1.0 0.7 0.8 12.7 2.3 0.1 1.3 0.2 7.6 0.4 6.5 18.3 0.1 12.3 13.9 14.5 15.4 0.1 22.0 12.8 14.4 4.6 3.8 0.1 0.2 38.0 8.6 3.1 3.0 0.5 4.4 2.9 2.2 0.6 0.0 0.2 0.1 4.2 2.7 1.5 28.9 33.0 1.0 16.4 27.3 43.5 24.9 15.4 0.7 58.8 17.7 1.7 25.8 27.3 29.5 6.2 55.3 14.9 146.2 15.6 56.9 110.3 9.1 2.8 2.1 65.5 0.0 10.0 115.9 11.8 5.0 32.1 26.2 2.5 21.1 1.1 1.7 40.3 0.0 6.7 83.2 34.6 6.8 3.3 282.5 7.2 8.8 17.8 3.7 14.2 2.1 21.6 1.5 1.2 103.6 102.2 9.8 11.4 37.1 178.4 11.5 3.7 2.4 0.0 2.2 3.4 56.6 2.9 62.6 53.3 32.3 18.5 2.5 93.0 59.9 MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560087-50731826 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;parathyroid gland: 51.0" "Cell type enhanced" "Detected in some" "Astrocytes: 202.7;Excitatory neurons: 105.2;Inhibitory neurons: 58.5;Late spermatids: 66.4;Muller glia cells: 62.6" "Cancer enriched" "Detected in many" 4 "glioma: 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;HeLa: 3.3;NTERA-2: 2.2;SCLC-21H: 11.6;SH-SY5Y: 2.8;SK-MEL-30: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" 0.9 26.8 56.5 0.2 79.9 0.0 0.8 56.4 46.0 1.5 28.0 6.8 0.6 0.8 3.1 2.3 1.5 1.8 22.1 41.6 57.5 3.3 4.5 2.3 0.0 65.4 70.0 2.9 1.4 51.0 17.8 2.6 56.7 5.0 0.8 22.6 0.9 9.8 1.5 1.3 1.6 1.8 48.8 0.1 2.1 2.4 81.9 7.3 6.2 1.5 0.0 4.6 1.3 38.7 0.0 0.0 1.0 0.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 1.1 1.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.6 2.8 0.0 0.8 1.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.5 79.9 56.4 46.0 41.6 57.5 65.4 70.0 56.7 48.8 81.9 38.7 0.4 9.6 0.0 202.7 0.0 0.0 0.4 0.0 0.0 11.4 0.9 1.1 22.9 1.5 0.0 0.0 0.0 4.6 0.0 0.0 5.9 0.9 30.1 0.0 0.0 0.3 0.0 0.0 105.2 0.0 0.3 1.0 0.0 0.0 0.0 0.7 0.0 1.0 0.4 5.0 58.5 0.0 0.0 0.0 0.0 66.4 0.9 0.1 0.0 7.5 0.0 62.6 0.0 18.6 1.9 0.4 0.0 1.5 0.0 0.7 0.0 0.2 0.0 1.0 0.0 1.0 0.7 0.8 0.6 0.0 0.0 1.8 0.0 0.4 0.0 0.1 MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067375 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 218.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005184, HPA030262, HPA047825" Approved Supported Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "CAB005184: AB_2140298, HPA030262: AB_10601868, HPA047825: " "unprognostic (6.61e-2)" "unprognostic (1.75e-2)" "unprognostic (5.05e-2)" "unprognostic (3.40e-3)" "unprognostic (2.72e-1)" "unprognostic (5.52e-2)" "unprognostic (6.13e-2)" "unprognostic (2.32e-3)" "unprognostic (3.99e-2)" "unprognostic (8.54e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-2)" "unprognostic (3.27e-3)" "unprognostic (2.03e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-2)" "unprognostic (2.31e-2)" 10.9 7.0 8.6 12.1 11.1 32.4 13.9 14.5 13.3 15.3 7.6 20.3 17.5 16.4 10.9 28.0 8.2 17.5 7.7 10.5 10.5 15.2 35.3 8.8 10.8 10.5 10.8 6.2 8.3 11.0 8.0 12.6 10.6 10.1 18.7 17.9 15.3 8.7 27.7 23.1 24.5 13.7 9.7 8.3 16.9 29.3 10.6 14.5 13.9 32.9 13.6 27.3 21.3 12.0 27.1 36.0 69.1 26.7 21.1 34.3 50.5 38.0 38.0 34.2 40.1 43.3 15.9 38.9 26.0 48.9 50.0 37.5 53.8 72.4 46.5 24.0 16.8 58.0 20.3 68.9 50.4 43.9 118.6 36.8 130.0 41.5 106.8 36.4 32.7 26.1 76.5 64.3 44.2 61.3 30.8 34.4 24.7 33.6 17.2 26.8 44.5 62.3 32.8 112.3 33.8 31.9 30.7 24.6 56.5 94.9 22.6 64.3 32.9 40.7 43.9 26.8 51.4 33.2 104.4 47.5 50.4 62.9 51.2 1.7 2.5 0.7 1.9 2.3 2.3 2.5 2.8 2.2 2.3 1.3 2.6 1.9 0.3 3.6 1.5 1.0 4.3 1.9 8.6 11.1 14.5 13.3 10.5 10.5 10.5 10.8 10.6 9.7 10.6 12.0 31.3 28.9 31.5 24.5 24.2 111.9 123.8 50.6 24.5 55.6 39.3 19.3 21.9 25.8 43.1 16.5 16.7 16.9 15.9 110.2 17.6 35.2 147.5 61.3 75.7 28.8 31.0 17.1 29.1 50.1 39.5 39.2 35.7 126.4 137.9 19.3 17.9 59.6 28.0 33.7 31.0 42.9 42.7 41.8 66.6 218.1 22.7 50.5 30.2 17.8 15.7 32.3 11.3 28.6 63.7 69.1 46.5 23.7 35.3 89.0 110.6 60.3 42.9 23.8 19.7 24.7 33.9 72.7 81.0 49.6 110.7 33.1 23.0 13.9 28.6 174.0 MAPK8IP1 "IB1, JIP-1, JIP1, PRKM8IP" ENSG00000121653 "Mitogen-activated protein kinase 8 interacting protein 1" Q9UQF2 11 45885651-45906465 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 166.8;pituitary gland: 118.2" "Cell type enhanced" "Detected in many" "Early spermatids: 43.8;Enteroendocrine cells: 40.2;Horizontal cells: 67.3;Late spermatids: 39.2;Muller glia cells: 41.3;Oligodendrocytes: 48.7" "Cancer enhanced" "Detected in all" "glioma: 51.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058921, HPA070332, HPA079657" Approved Enhanced "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA058921: AB_2683854, HPA070332: AB_2686254, HPA079657: " "unprognostic (3.96e-2)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (6.88e-2)" "unprognostic (5.59e-2)" "unprognostic (2.82e-1)" "unprognostic (8.25e-3)" "unprognostic (3.42e-3)" "unprognostic (1.27e-2)" "unprognostic (9.54e-2)" "unprognostic (3.22e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.23e-11)" "unprognostic (7.19e-2)" "unprognostic (4.01e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-3)" 4.8 23.3 127.9 2.3 131.0 1.3 4.8 122.0 147.7 8.2 29.6 8.3 1.4 10.9 3.5 2.2 11.3 3.5 5.5 166.8 120.6 11.5 5.6 4.0 0.6 154.9 130.9 9.1 43.1 19.2 118.2 1.4 142.6 11.6 1.2 11.5 11.4 6.1 2.4 4.0 3.7 5.7 124.6 2.3 9.0 27.7 139.3 1.0 7.0 2.5 0.4 6.7 4.8 164.4 0.0 7.1 9.4 26.2 3.4 1.8 0.3 5.1 4.6 9.9 7.2 6.3 1.1 0.4 2.5 5.9 16.8 5.8 10.2 4.8 4.4 4.0 13.1 0.1 8.6 4.1 3.1 0.6 4.4 2.4 1.0 6.4 1.3 6.6 2.2 0.9 11.5 1.6 2.8 3.9 0.4 0.6 24.9 3.3 10.5 0.6 15.4 0.3 4.6 0.2 76.4 28.5 8.4 6.8 10.0 3.6 11.0 0.4 2.1 12.5 19.1 19.0 9.3 1.1 1.3 0.5 7.9 0.2 3.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 127.9 131.0 122.0 147.7 166.8 120.6 154.9 130.9 142.6 124.6 139.3 164.4 1.7 6.4 4.1 7.2 0.9 2.4 5.8 2.0 2.8 34.4 6.1 5.3 1.1 5.7 3.3 11.0 22.9 1.6 0.4 2.2 13.7 6.9 43.8 23.9 15.9 2.9 40.2 0.0 10.3 28.9 0.6 6.5 4.1 19.9 0.0 2.8 0.4 4.6 0.5 67.3 11.6 1.6 4.1 0.8 3.5 39.2 6.2 1.1 3.6 1.0 1.6 41.3 0.0 3.5 48.7 11.6 0.5 6.4 0.1 6.3 1.4 8.9 10.9 18.3 0.0 14.2 6.0 10.6 8.2 0.9 1.0 5.7 1.3 7.7 0.9 5.5 MAPK8IP2 "IB2, JIP2, PRKM8IPL" ENSG00000008735 "Mitogen-activated protein kinase 8 interacting protein 2" Q13387 22 50600793-50613981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 84.0;pituitary gland: 35.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.8;Enteroendocrine cells: 32.3;Horizontal cells: 99.3;Rod photoreceptor cells: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 19.3;HEK 293: 11.0;SCLC-21H: 15.7;SH-SY5Y: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034780 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA034780: AB_10670283" "unprognostic (7.82e-2)" "unprognostic (7.62e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (5.80e-2)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (2.90e-1)" "unprognostic (5.23e-2)" "unprognostic (9.19e-2)" "unprognostic (8.57e-3)" "unprognostic (8.78e-3)" "unprognostic (6.33e-3)" "unprognostic (6.77e-2)" "unprognostic (1.72e-1)" "unprognostic (5.29e-2)" "unprognostic (4.75e-2)" 1.4 9.2 54.7 0.3 50.2 0.0 1.4 27.5 67.8 1.4 0.0 2.1 0.2 2.1 0.3 1.2 1.5 0.0 0.4 53.7 35.1 0.7 0.5 0.5 0.0 78.0 27.0 7.0 1.8 2.0 35.2 0.3 84.0 1.9 0.1 9.6 2.8 0.2 0.3 1.5 1.0 0.2 18.6 0.8 1.5 7.1 39.4 0.2 1.0 0.1 0.0 0.3 1.0 49.2 0.3 1.1 4.7 4.1 0.4 0.0 3.7 0.0 0.0 1.0 0.6 2.4 0.8 0.6 1.0 0.0 19.3 0.0 6.6 0.0 0.0 0.3 11.0 0.0 0.4 1.2 0.5 0.0 0.8 0.3 5.5 0.0 0.1 0.0 0.0 0.1 1.1 1.8 0.0 0.0 0.0 0.0 3.4 0.8 1.8 1.1 0.7 0.0 0.0 0.1 15.7 19.8 3.7 4.6 0.2 0.9 0.9 0.0 0.0 0.1 0.1 0.6 0.0 1.1 3.1 0.5 0.5 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.2 27.5 67.8 53.7 35.1 78.0 27.0 84.0 18.6 39.4 49.2 0.6 3.2 2.0 6.5 0.1 0.4 1.6 0.5 0.6 57.8 2.3 3.9 2.3 2.8 2.7 0.0 16.7 0.2 0.0 0.5 0.0 3.0 0.6 0.7 1.7 0.7 32.3 0.0 15.6 2.5 1.1 0.7 0.0 1.5 0.0 0.5 0.0 0.3 0.1 99.3 13.1 0.5 4.1 0.0 0.4 1.8 5.9 0.3 7.2 3.7 0.2 11.2 0.0 6.0 3.2 0.7 0.1 0.7 0.1 1.2 0.3 0.7 0.3 26.7 0.0 1.3 1.0 3.4 2.7 0.6 0.6 1.1 0.3 0.5 0.6 0.5 MAPKAPK3 "3pK, MAPKAP3, MK-3, MK3" ENSG00000114738 "MAPK activated protein kinase 3" Q16644 3 50611520-50649291 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 106.5;heart muscle: 256.3;skeletal muscle: 224.2;tongue: 284.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 226.6;Hofbauer cells: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 142.8;granulocytes: 126.3;monocytes: 341.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA058275: AB_2683663" "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favorable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" 15.3 43.3 18.0 29.8 19.6 106.5 15.8 19.2 19.2 15.0 21.3 19.7 30.2 11.3 10.3 49.6 15.1 12.1 256.3 18.0 19.7 40.0 18.7 28.2 21.7 23.6 20.5 14.2 36.2 47.2 23.5 13.9 22.5 18.4 20.0 4.7 27.7 12.6 224.2 53.4 24.2 15.9 21.6 25.3 27.6 9.2 21.1 42.0 41.2 284.3 24.2 20.3 22.2 21.6 99.6 30.3 12.4 35.9 18.4 45.7 27.9 23.8 33.7 35.7 30.3 47.1 90.2 39.8 23.5 79.5 88.5 34.6 85.9 92.7 31.9 88.3 22.3 209.5 40.6 43.5 36.8 152.1 106.4 36.9 57.0 83.1 112.2 35.6 31.9 70.2 59.7 25.4 76.1 40.5 65.3 153.3 46.4 34.6 127.0 28.5 29.9 60.1 165.5 56.2 23.0 16.5 21.3 58.9 27.7 20.6 37.8 93.4 23.8 28.1 64.5 146.4 59.5 17.2 33.7 33.1 148.3 234.7 11.8 45.3 169.5 126.3 27.6 271.6 27.3 15.1 30.9 32.1 142.8 8.8 23.9 27.8 104.4 42.1 341.5 91.2 28.0 132.6 18.0 19.6 19.2 19.2 18.0 19.7 23.6 20.5 22.5 21.6 21.1 21.6 3.5 9.6 14.0 8.5 8.6 11.3 26.9 14.0 19.4 1.1 15.3 12.3 226.6 15.7 10.4 11.0 0.0 6.0 38.1 16.2 64.6 45.6 34.5 3.4 2.7 7.1 6.0 19.1 0.3 30.4 7.4 14.9 11.7 5.4 36.2 8.3 5.3 14.2 102.1 0.0 0.7 15.4 10.2 68.0 23.9 86.2 7.2 59.4 7.2 0.0 76.6 17.1 41.2 0.5 2.0 76.2 15.6 3.4 12.7 30.9 30.7 35.4 5.7 2.3 26.3 9.7 12.0 4.1 4.6 34.2 20.2 5.1 24.3 22.0 28.2 33.5 MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 43.8;Syncytiotrophoblasts: 98.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.5;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 40.4;HUVEC TERT2: 27.4;TIME: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 5.6 2.8 6.1 2.9 5.6 3.7 2.6 5.3 4.1 0.9 1.9 5.3 0.9 1.4 0.0 1.4 1.5 5.2 7.8 3.9 5.7 0.8 0.7 2.4 2.5 11.5 7.1 1.1 2.4 0.3 2.4 1.7 7.9 0.6 5.6 7.4 4.6 0.2 6.5 5.8 2.4 2.9 8.3 1.6 2.4 5.6 7.8 1.3 1.4 3.3 2.1 7.6 0.7 8.5 0.4 1.8 3.9 2.1 3.4 3.2 1.2 14.2 5.9 11.1 16.3 1.9 0.8 3.8 1.3 1.9 2.4 1.1 4.9 2.5 15.3 0.8 4.7 12.2 3.2 1.9 5.6 5.0 3.0 2.4 0.7 40.4 4.8 2.6 27.4 0.6 5.1 0.7 9.3 1.3 0.5 2.3 3.3 3.0 4.6 1.5 15.5 1.2 0.9 2.0 1.3 0.9 3.3 0.5 1.6 1.9 2.9 5.0 33.5 2.2 1.8 12.6 1.6 1.9 2.3 2.3 8.3 3.8 2.0 0.0 0.2 2.8 0.5 0.4 0.1 10.5 0.6 0.3 0.1 12.1 2.3 0.5 0.8 2.3 0.3 0.7 2.9 0.8 6.1 5.6 5.3 4.1 3.9 5.7 11.5 7.1 7.9 8.3 7.8 8.5 3.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 43.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 98.6 0.6 0.0 0.0 0.0 MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 94.9;lung: 199.6;lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 6 "Kupffer cells: 1269.8" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Group enriched" "Detected in many" 4 "cerebral cortex: 4.1;thalamus: 12.6" "Group enriched" "Detected in some" 4 "classical monocyte: 33.7;intermediate monocyte: 56.5" "Lineage enriched" "Detected in many" 5 "monocytes: 56.5" "Cell line enhanced" "Detected in some" "HaCaT: 1.7;THP-1: 2.5;U-2 OS: 2.6;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" 64.7 31.1 0.4 87.9 1.4 3.4 7.4 0.7 4.1 0.7 4.4 5.7 2.0 0.7 1.3 2.4 25.5 2.4 19.0 0.9 1.0 1.6 94.9 199.6 17.7 1.2 1.7 7.5 0.8 0.3 1.5 2.8 1.9 1.8 2.1 0.0 4.4 2.3 1.5 2.5 3.1 29.8 1.2 37.1 3.5 2.0 12.6 1.3 1.5 5.0 1.1 25.2 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.6 0.4 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 33.7 0.0 0.0 56.5 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.7 0.0 7.2 1.0 0.0 9.2 0.4 1.4 0.7 4.1 0.9 1.0 1.2 1.7 1.9 1.2 12.6 0.7 0.7 25.6 45.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 3.4 1.8 0.4 1.5 16.7 3.7 0.0 0.7 1.4 0.1 0.0 3.9 0.0 0.0 0.0 5.2 0.0 8.0 0.0 0.2 1.1 2.6 0.0 0.0 12.6 0.0 11.4 3.4 169.6 0.0 0.0 0.0 0.0 1269.8 46.4 0.1 0.0 199.3 0.0 2.8 23.2 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.5 0.1 0.0 0.2 13.1 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.9 1.9 4.1 0.0 0.0 0.1 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911020 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: AB_2686722" "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 11.3 13.8 12.6 21.1 16.1 24.0 16.8 8.1 16.3 18.5 10.8 25.9 26.1 14.6 7.7 51.8 16.6 14.1 20.9 14.9 9.3 13.9 13.1 17.0 21.5 11.8 9.3 12.0 22.4 19.4 19.8 14.9 11.5 20.5 22.4 8.8 27.0 13.1 20.8 40.9 25.1 16.3 7.3 24.1 20.9 10.6 9.5 23.2 19.5 13.7 24.0 19.3 25.0 17.9 52.0 34.1 26.6 28.6 14.6 18.6 35.2 20.8 20.0 29.5 22.3 34.1 49.5 37.8 35.6 20.8 32.0 57.5 26.9 28.7 24.6 26.7 20.9 40.7 23.9 20.3 17.0 45.9 51.4 10.9 36.8 27.0 21.4 13.5 24.7 33.6 35.7 36.5 19.5 64.4 49.3 29.9 31.7 36.0 24.2 39.9 20.4 39.7 19.1 39.8 37.9 25.4 34.7 90.2 24.3 28.9 65.1 26.4 22.7 30.3 19.1 39.6 23.4 24.5 28.8 36.7 20.1 23.2 25.3 1.4 0.7 2.1 1.3 0.7 2.1 0.9 1.0 1.3 1.0 1.6 0.8 0.9 3.6 1.6 1.1 0.9 0.6 0.7 12.6 16.1 8.1 16.3 14.9 9.3 11.8 9.3 11.5 7.3 9.5 17.9 17.3 6.4 6.8 29.7 18.5 25.2 21.1 9.1 19.4 26.8 30.0 18.2 12.8 27.1 11.9 20.2 8.4 26.0 33.4 90.3 1.9 20.2 0.6 29.5 15.8 14.7 29.9 14.7 43.6 21.4 20.6 11.7 27.0 41.0 17.2 21.1 13.6 13.0 17.9 20.2 30.3 39.9 10.2 26.7 18.5 0.9 12.8 25.0 3.6 29.0 17.0 18.8 36.0 31.7 51.8 27.3 39.4 10.9 15.6 30.4 33.4 8.1 14.5 18.1 19.7 19.6 13.1 9.1 18.4 39.9 34.4 65.0 23.6 16.0 33.6 44.3 MARVELD2 "DFNB49, FLJ30532, MRVLDC2, TRIC" ENSG00000152939 "MARVEL domain containing 2" Q8N4S9 5 69415065-69444330 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Urothelial cells: 46.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.5;CAPAN-2: 24.1;HaCaT: 18.9;RT4: 21.1;SCLC-21H: 26.7;T-47d: 18.3" "Region enriched" "Detected in some" 8 "cerebellum: 7.9" "Low region specificity" "Detected in all" "HPA018119, HPA061726" Uncertain Supported "Cell Junctions" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA018119: AB_2669771, HPA061726: AB_2684595" "unprognostic (4.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.44e-3)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" "unprognostic (8.84e-2)" "unprognostic (2.43e-1)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "prognostic favorable (2.84e-13)" "unprognostic (1.78e-1)" "unprognostic (1.19e-1)" "unprognostic (3.67e-2)" "unprognostic (1.82e-1)" 0.3 0.2 0.5 0.9 0.5 0.2 4.0 0.5 0.6 2.1 3.2 5.7 7.7 1.1 1.3 6.9 3.9 2.9 0.4 0.5 0.5 8.0 10.7 5.6 0.1 0.7 0.7 0.1 9.3 4.6 2.9 1.8 0.7 3.0 6.2 0.3 4.6 2.6 0.0 4.3 7.7 0.4 0.4 0.2 8.1 1.5 0.7 1.0 15.7 0.0 1.3 3.0 3.4 0.7 10.8 3.5 0.1 0.0 0.0 0.0 29.5 0.2 0.2 0.2 0.7 14.1 24.1 0.1 2.0 1.8 0.0 18.9 0.0 14.0 0.5 0.2 5.8 0.0 1.1 7.8 1.7 0.0 0.1 0.4 15.3 0.1 1.9 0.7 0.9 0.1 0.0 0.1 0.0 9.8 0.0 0.0 1.8 6.3 0.3 0.0 0.1 0.5 10.0 21.1 26.7 0.0 2.3 2.0 0.3 4.3 18.3 0.0 1.5 0.0 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.6 0.5 0.5 0.7 0.7 0.7 0.4 0.7 0.7 1.0 22.4 26.5 0.7 1.0 5.0 22.2 14.8 10.2 0.3 15.5 8.5 2.8 35.8 23.1 16.5 2.1 22.9 0.2 31.4 17.6 25.1 5.8 33.5 3.4 4.1 16.8 3.4 0.5 25.8 8.2 1.1 17.9 30.4 1.3 3.7 5.0 37.9 1.9 0.0 0.4 23.1 18.3 0.6 0.9 3.2 0.0 0.6 1.8 1.0 7.8 0.5 0.0 0.5 0.6 25.0 29.7 0.0 0.6 25.5 33.5 6.1 38.4 0.6 0.0 0.8 1.5 4.1 2.4 19.4 6.5 12.0 0.9 2.9 25.6 46.9 MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 150.1;Intestinal goblet cells: 68.2;Paneth cells: 102.9;Proximal enterocytes: 199.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 21.7;BEWO: 30.9;CACO-2: 23.6;CAPAN-2: 22.5;HaCaT: 21.4;MCF7: 40.8;RT4: 18.8;SK-BR-3: 18.5;T-47d: 26.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 17: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "Intermediate filaments" "HPA043514: AB_10959475, HPA045471: " "unprognostic (1.18e-1)" "unprognostic (3.92e-1)" "unprognostic (9.92e-2)" "unprognostic (5.56e-2)" "unprognostic (1.03e-1)" "unprognostic (6.16e-3)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (2.54e-1)" "unprognostic (8.75e-3)" "unprognostic (3.29e-1)" "unprognostic (5.16e-2)" "prognostic favorable (6.80e-10)" "unprognostic (2.63e-3)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "unprognostic (2.43e-1)" 0.2 0.3 0.5 3.1 0.6 0.6 6.2 1.8 0.9 4.0 6.5 23.6 31.1 1.8 7.3 4.2 4.2 4.8 0.3 1.1 0.5 12.9 5.3 2.4 0.5 0.4 0.5 0.5 17.1 12.5 1.0 5.7 0.5 6.0 18.7 2.1 11.6 2.5 0.8 3.3 33.1 0.6 0.1 0.4 2.8 0.9 0.5 0.9 3.9 0.0 1.7 3.8 2.5 0.9 21.7 0.7 0.5 0.9 0.0 0.1 30.9 0.0 0.0 0.0 0.0 23.6 22.5 0.2 2.3 0.0 0.1 21.4 1.9 10.3 0.1 0.0 12.1 0.0 0.4 6.2 0.0 0.1 0.2 0.9 12.5 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.0 40.8 0.2 0.3 3.5 13.4 0.2 0.0 0.1 8.8 0.3 18.8 3.7 0.2 0.4 18.5 0.0 2.4 26.3 0.3 0.0 0.0 0.4 0.4 0.2 0.2 0.3 0.1 0.2 0.2 0.2 1.8 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.4 0.2 0.2 1.2 0.4 0.1 0.3 0.2 0.1 0.5 0.6 1.8 0.9 1.1 0.5 0.4 0.5 0.5 0.1 0.5 0.9 0.3 9.6 8.4 0.3 0.8 7.9 28.7 9.6 22.8 7.0 25.4 10.7 0.6 40.0 17.9 9.2 0.0 36.5 1.5 150.1 1.9 29.8 4.4 14.2 1.5 1.0 61.5 0.0 0.6 33.7 2.5 1.5 6.1 19.4 0.0 3.8 0.4 9.1 3.1 0.0 0.6 68.2 14.2 1.0 1.0 3.3 0.3 1.2 0.0 0.0 0.8 1.0 0.0 0.0 0.6 26.3 102.9 0.7 0.0 38.4 199.3 27.6 17.4 19.6 0.0 4.1 1.6 9.6 5.0 19.6 3.7 4.8 1.4 0.0 61.3 44.3 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874952 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 37.7;pituitary gland: 23.3;retina: 15.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.7;Cone photoreceptor cells: 43.8;Excitatory neurons: 64.7;Inhibitory neurons: 70.3;Oligodendrocyte precursor cells: 22.1;Rod photoreceptor cells: 20.4" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Region enhanced" "Detected in many" "cerebral cortex: 37.7" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "AN3-CA: 23.3;SCLC-21H: 40.5;SH-SY5Y: 20.2;U-266/70: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "HPA028181: AB_10603872, HPA073106: AB_2732218" "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 0.0 2.2 6.5 0.3 12.1 0.3 0.1 7.3 37.7 0.2 0.0 1.2 0.3 0.0 0.0 0.2 0.1 0.2 0.2 8.3 2.4 0.1 0.6 0.1 0.1 11.2 1.1 0.3 0.6 0.5 23.3 0.0 9.5 0.2 0.1 15.4 0.2 0.0 0.0 3.7 0.4 0.0 0.0 0.1 0.6 5.0 1.2 0.8 0.1 0.0 0.0 0.2 0.3 3.0 3.6 1.6 1.5 23.3 0.0 0.0 1.9 0.2 0.1 0.3 0.9 0.8 1.5 5.8 2.6 0.0 3.9 0.1 6.8 0.1 0.1 4.1 4.5 0.5 5.8 2.6 0.0 1.3 1.2 0.5 0.1 0.8 0.7 1.3 0.0 15.2 5.2 3.0 0.0 0.8 2.4 0.6 6.9 0.6 7.2 15.9 4.6 8.3 0.3 0.2 40.5 20.2 0.8 1.4 4.3 1.2 3.8 2.1 0.0 2.8 4.2 3.1 0.8 16.7 14.5 3.7 5.1 3.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 6.5 12.1 7.3 37.7 8.3 2.4 11.2 1.1 9.5 0.0 1.2 3.0 0.5 0.0 2.4 7.8 0.2 0.9 1.6 0.6 0.6 24.7 0.8 2.5 1.0 0.0 0.3 0.0 43.8 0.6 0.4 0.6 0.0 0.4 14.0 0.2 0.2 1.3 0.0 0.0 64.7 0.5 0.6 1.3 0.0 0.3 1.3 0.5 1.1 0.5 0.2 15.2 70.3 0.1 0.0 1.0 1.2 8.2 0.6 0.7 5.4 6.5 0.1 3.7 0.0 22.1 3.0 0.3 2.5 1.2 0.0 1.0 0.9 0.2 1.0 20.4 0.0 2.0 0.5 8.0 5.2 0.7 1.4 0.3 1.0 0.4 0.7 1.2 MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 201.0;Peritubular cells: 258.8;Theca cells: 297.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Cell line enhanced" "Detected in many" "BJ: 72.5;BJ hTERT+ SV40 Large T+: 78.6;BJ hTERT+ SV40 Large T+ RasG12V: 106.7;HaCaT: 114.4;HBF TERT88: 100.6;SuSa: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" NA NA 1500000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" 54.4 51.0 24.3 30.2 22.5 1.8 43.6 17.6 23.2 194.4 19.3 67.5 58.5 147.0 101.6 32.8 46.9 40.1 110.2 20.0 23.4 39.3 24.6 15.2 18.0 24.1 30.5 116.4 11.3 28.0 9.9 177.9 26.3 104.9 57.8 45.7 42.6 171.9 4.0 62.8 80.6 98.1 18.3 5.9 23.7 31.2 23.4 4.9 271.4 28.5 15.4 103.0 139.2 30.8 24.1 10.8 23.3 2.5 60.7 3.6 15.0 72.5 17.6 78.6 106.7 13.0 8.4 0.1 7.0 29.2 3.5 114.4 2.3 4.4 100.6 0.0 2.9 0.8 6.1 0.9 14.0 0.0 0.0 13.6 9.5 16.1 0.8 22.1 0.5 1.3 0.1 0.2 4.1 11.2 0.0 0.7 7.1 0.3 3.7 0.0 2.4 11.4 5.7 5.3 16.0 1.5 11.5 0.2 19.8 67.3 10.9 1.4 0.6 5.2 31.5 16.1 11.0 0.9 0.2 0.2 18.8 0.4 5.9 0.0 0.1 0.1 0.2 0.4 5.2 0.0 0.7 0.9 0.8 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 24.3 22.5 17.6 23.2 20.0 23.4 24.1 30.5 26.3 18.3 23.4 30.8 27.8 3.2 1.3 11.1 0.3 37.3 10.1 6.2 80.2 6.3 3.8 45.8 29.1 18.6 3.0 16.5 54.2 1.2 0.2 20.6 0.0 9.9 86.0 4.2 22.6 32.4 23.4 3.2 6.4 0.0 1.1 113.1 5.1 5.0 0.0 43.5 201.0 11.0 1.6 0.0 11.5 25.4 0.0 5.0 7.7 108.6 103.5 0.9 28.4 19.7 2.0 8.1 0.0 86.0 59.8 3.2 18.2 258.8 0.0 6.5 118.7 3.4 1.6 52.9 13.1 97.2 17.1 2.5 2.6 7.3 8.5 2.5 2.0 297.5 27.4 1.8 MATN4 ENSG00000124159 "Matrilin 4" O95460 20 45293445-45308529 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "pancreas: 24.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Fibroblasts: 8.5;Langerhans cells: 6.3;Spermatogonia: 4.9;Suprabasal keratinocytes: 4.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 2.5;U-937: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 14000 "Cluster 25: Pancreas - Digestion" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.54e-1)" "unprognostic (2.39e-2)" "unprognostic (2.22e-2)" "unprognostic (3.60e-2)" "unprognostic (8.38e-2)" "unprognostic (9.67e-2)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (6.27e-2)" "unprognostic (6.74e-3)" "unprognostic (5.53e-1)" "unprognostic (6.19e-3)" "unprognostic (3.63e-6)" "unprognostic (2.38e-1)" "unprognostic (4.69e-2)" "unprognostic (4.27e-1)" "unprognostic (5.38e-2)" 0.7 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 24.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.4 0.0 3.2 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.1 0.1 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 6.4 0.7 1.0 0.0 0.0 1.6 1.9 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.1 0.7 0.2 0.4 0.0 0.0 1.0 2.5 0.0 8.5 1.1 0.8 0.0 0.3 0.4 0.2 0.1 0.0 0.4 0.1 0.0 0.0 6.3 0.5 0.0 0.1 1.8 1.0 0.0 0.0 0.0 3.0 0.4 0.9 0.1 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.4 0.4 1.6 4.9 0.3 4.3 0.3 0.3 0.1 0.2 1.0 MB PVALB ENSG00000198125 Myoglobin P02144 22 35606764-35637951 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Muscle protein" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 38 "heart muscle: 13154.5;skeletal muscle: 40709.4;tongue: 29085.2" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 5182.1" "Group enriched" "Detected in many" 7 "breast cancer: 13.6;head and neck cancer: 31.1;prostate cancer: 30.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 6 "NK-cells: 1.3" "Cell line enriched" "Detected in some" 4 "SK-BR-3: 175.6" "Low region specificity" "Detected in many" "CAB000060, HPA003123" Enhanced NA NA 13500000 140000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB000060: , HPA003123: AB_1079442" "unprognostic (7.51e-2)" "unprognostic (3.92e-3)" "unprognostic (1.07e-1)" "unprognostic (7.71e-2)" "unprognostic (2.35e-1)" "unprognostic (4.66e-3)" "unprognostic (5.78e-3)" "unprognostic (1.18e-1)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (2.74e-3)" "unprognostic (1.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.51e-2)" "unprognostic (2.35e-1)" "unprognostic (3.44e-3)" "unprognostic (1.19e-2)" 8.1 4.6 1.2 1.5 1.2 0.3 43.4 1.2 2.2 2.9 0.9 14.6 1.8 2.3 0.3 736.1 18.7 4.1 13154.5 1.0 1.9 2.8 5.8 14.9 5.3 1.4 1.4 5.3 26.9 16.1 10.6 3.1 1.2 214.2 12.9 0.2 367.1 0.5 40709.4 23.0 11.1 1.4 1.2 2.1 3.8 4.5 1.5 0.8 8.5 29085.2 1.8 1.3 4.5 1.0 1.9 7.6 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 4.6 0.7 0.1 0.3 1.0 0.8 0.2 0.0 0.0 5.4 0.3 0.1 0.5 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.5 0.5 0.0 19.2 0.1 0.6 0.0 1.9 2.3 0.9 0.5 8.0 0.0 6.4 1.5 0.2 19.0 175.6 0.0 0.3 39.4 0.1 0.4 0.5 1.2 2.2 0.2 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.2 1.0 1.9 1.4 1.4 1.2 1.2 1.5 1.0 0.3 0.0 0.0 0.3 0.1 0.3 4.3 12.5 0.0 0.0 30.7 23.9 5182.1 0.0 30.8 0.0 0.0 0.1 0.5 3.8 0.0 4.7 20.1 20.2 0.1 40.7 11.5 0.0 0.0 0.2 0.0 145.2 0.0 0.2 0.0 0.8 0.0 0.4 0.0 0.0 0.1 114.6 14.2 0.0 0.4 70.0 0.0 2.1 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.7 0.0 21.8 2.6 0.1 19.9 0.0 0.0 420.9 42.0 0.3 0.7 0.6 0.1 0.3 2.8 0.1 2.9 15.1 MB21D2 C3orf59 ENSG00000180611 "Mab-21 domain containing 2" Q8IYB1 3 192796815-192917856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.8;Inhibitory neurons: 53.0;Langerhans cells: 85.0;Oligodendrocyte precursor cells: 68.9;Syncytiotrophoblasts: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 4.2;T-reg: 3.9" "Lineage enriched" "Detected in single" 9 "T-cells: 4.2" "Cell line enhanced" "Detected in many" "HDLM-2: 114.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044026 Approved Approved Cytosol NA Yes "Cluster 13: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA044026: AB_10962840" "unprognostic (3.52e-2)" "unprognostic (1.02e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (3.74e-5)" "unprognostic (2.42e-2)" "prognostic unfavorable (9.94e-4)" "unprognostic (2.76e-2)" "unprognostic (3.50e-2)" "unprognostic (1.53e-1)" "unprognostic (2.46e-1)" "unprognostic (2.84e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-3)" "unprognostic (5.94e-3)" "unprognostic (1.95e-1)" "unprognostic (3.80e-2)" "unprognostic (3.28e-2)" 3.7 4.2 2.5 3.2 2.8 1.3 3.4 3.3 3.1 2.8 1.6 3.0 8.8 5.1 1.9 2.0 3.6 4.7 4.0 2.8 2.3 4.2 1.5 3.6 1.2 2.1 2.0 4.1 1.9 2.3 3.5 13.3 1.8 1.9 2.9 2.0 1.5 1.9 2.7 4.7 9.3 5.6 1.5 2.2 3.5 7.1 1.9 1.4 1.7 1.6 1.7 8.8 2.4 2.3 26.6 3.7 6.3 19.0 3.9 5.8 11.2 18.8 17.5 33.4 19.9 17.0 4.2 0.0 11.0 46.6 13.8 11.5 14.6 4.8 36.2 114.8 8.1 3.3 1.8 2.0 7.4 0.4 1.6 7.6 7.4 9.4 5.8 2.7 6.6 3.3 0.2 1.5 5.8 19.8 0.3 0.0 13.1 14.4 45.9 0.6 10.5 5.6 7.8 15.1 9.8 5.0 4.1 12.8 1.9 12.9 19.9 0.4 2.1 6.3 18.4 11.1 36.3 48.1 41.0 0.0 4.4 4.0 8.6 0.0 0.2 0.0 0.2 0.3 1.9 0.1 4.2 1.0 0.4 0.0 2.6 0.7 0.0 0.0 0.0 0.0 3.9 0.9 2.5 2.8 3.3 3.1 2.8 2.3 2.1 2.0 1.8 1.5 1.9 2.3 2.9 6.4 0.5 16.6 1.2 9.2 0.9 2.0 1.2 10.9 4.6 3.2 1.8 1.5 3.2 0.0 2.1 63.8 0.3 2.4 0.0 6.5 0.2 12.4 2.0 7.7 10.2 0.0 28.6 0.2 9.5 5.9 1.5 15.9 0.0 5.8 9.7 0.2 5.6 8.4 53.0 2.8 4.1 3.8 85.0 1.4 3.1 10.4 14.2 17.8 13.4 1.1 0.0 68.9 30.6 2.2 6.1 6.0 4.2 0.8 15.4 9.6 2.8 1.3 13.1 3.3 4.5 1.8 16.5 1.8 8.7 110.4 3.3 5.4 3.7 2.6 MBNL3 "CHCR, FLJ11316, MBLX39, MBXL" ENSG00000076770 "Muscleblind like splicing regulator 3" Q9NUK0 X 132369317-132489968 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 59.3;placenta: 170.8" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 328.3;Hepatocytes: 119.6;Syncytiotrophoblasts: 344.1" "Cancer enhanced" "Detected in all" "liver cancer: 13.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 123.8;Hep G2: 171.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001584 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Golgi apparatus" "HPA001584: AB_1079326" "unprognostic (3.38e-2)" "unprognostic (1.40e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.57e-4)" "unprognostic (1.87e-1)" "unprognostic (2.67e-3)" "unprognostic (8.74e-2)" "unprognostic (3.46e-2)" "unprognostic (2.19e-2)" "unprognostic (5.77e-3)" "unprognostic (4.36e-3)" "unprognostic (1.65e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" "unprognostic (2.43e-1)" "unprognostic (8.28e-2)" "unprognostic (2.37e-1)" 6.8 11.6 1.3 8.7 1.9 14.8 4.7 1.7 1.0 3.7 2.4 11.7 9.9 4.9 24.3 10.9 9.4 5.7 9.7 1.1 4.4 8.0 59.3 5.9 13.8 3.6 3.1 4.8 10.0 4.2 1.6 170.8 3.2 4.0 11.5 0.1 6.6 11.1 0.6 12.6 9.8 4.0 2.0 11.3 13.0 42.8 1.6 14.3 8.2 3.4 15.1 8.5 2.8 3.7 7.2 0.0 8.6 1.4 1.6 3.6 15.7 0.5 3.2 1.1 0.0 123.8 22.7 32.6 0.7 1.3 1.1 7.7 19.8 8.2 0.8 3.3 7.6 29.1 25.9 171.5 1.5 32.9 10.2 1.5 7.1 0.0 3.6 0.1 1.1 20.4 2.6 9.2 1.6 19.2 56.3 12.5 1.3 27.5 1.6 53.2 10.7 18.6 5.7 18.6 3.1 10.5 14.8 8.6 4.3 15.1 3.1 8.4 3.9 6.3 1.2 8.2 6.7 18.2 13.0 47.0 1.2 21.8 20.2 11.9 7.9 5.5 16.6 9.9 14.4 20.6 9.8 11.6 8.8 25.5 10.0 11.2 1.2 18.7 21.7 17.0 2.2 9.1 1.3 1.9 1.7 1.0 1.1 4.4 3.6 3.1 3.2 2.0 1.6 3.7 4.1 3.2 6.8 16.0 16.9 8.8 2.2 2.1 5.2 0.7 3.5 3.6 14.7 41.5 5.0 11.0 0.0 328.3 9.5 12.8 3.9 1.5 5.8 12.6 1.3 3.6 6.7 55.8 0.9 5.4 56.6 7.5 15.3 6.6 8.8 6.8 6.4 119.6 29.3 0.0 0.9 9.8 0.0 27.2 6.5 9.4 23.0 9.6 7.2 30.0 10.6 0.2 9.2 0.0 20.6 1.3 3.6 50.8 12.2 1.4 6.4 9.7 4.5 1.9 0.0 3.1 2.7 2.1 1.7 13.6 8.5 344.1 10.3 5.7 10.3 3.3 MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.4;lymphoid tissue: 1.0" "Cell type enriched" "Detected in single" 17 "Squamous epithelial cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-138 MG: 1.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA042365: AB_2677961, HPA058088: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 MCCC1 MCCA ENSG00000078070 "Methylcrotonoyl-CoA carboxylase 1" Q96RQ3 3 183015218-183116075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 153.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008310 Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA008310: AB_1853620" "unprognostic (4.01e-2)" "unprognostic (1.83e-3)" "unprognostic (2.05e-2)" "unprognostic (2.59e-3)" "unprognostic (3.46e-2)" "unprognostic (4.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-3)" "unprognostic (2.57e-3)" "unprognostic (9.82e-2)" "unprognostic (9.74e-2)" "unprognostic (7.65e-2)" "prognostic favorable (3.68e-4)" "unprognostic (4.73e-1)" "unprognostic (2.21e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" 37.9 22.6 9.5 9.5 10.9 13.9 33.2 9.9 13.4 12.3 13.8 17.4 16.1 10.1 14.6 17.6 12.2 11.9 34.2 9.2 9.3 58.8 59.3 17.9 11.7 9.5 9.1 17.2 31.2 18.7 8.4 6.3 10.6 15.1 18.6 10.8 18.0 13.4 21.9 12.2 13.8 10.6 9.3 11.8 21.7 9.1 11.1 16.0 18.9 26.3 15.5 26.5 9.4 13.3 43.1 16.5 10.3 10.6 42.6 19.1 20.4 19.5 26.4 21.1 23.5 22.9 17.1 47.6 31.0 17.2 35.8 22.0 15.4 12.9 26.4 16.6 17.0 40.0 18.3 23.9 28.7 27.5 22.0 21.6 14.5 10.0 23.3 14.0 28.6 40.7 22.7 24.7 23.6 35.4 27.1 15.9 11.2 66.3 17.9 22.4 22.6 60.1 32.2 67.2 22.0 16.4 75.3 100.1 21.1 10.7 153.9 37.8 14.0 15.8 12.5 12.8 28.6 24.3 48.8 48.2 16.8 38.4 15.2 14.4 13.3 25.0 10.7 15.6 12.3 17.9 14.1 11.8 26.6 15.4 14.7 13.1 2.1 25.4 16.8 17.3 9.6 10.7 9.5 10.9 9.9 13.4 9.2 9.3 9.5 9.1 10.6 9.3 11.1 13.3 6.2 9.6 53.9 44.7 14.6 7.0 20.1 17.9 15.9 13.0 10.6 9.5 32.8 31.5 20.2 27.6 10.4 35.4 6.3 7.2 33.2 25.3 5.4 11.0 10.2 6.6 6.0 10.9 66.6 17.2 5.4 10.3 21.4 21.9 7.6 19.0 6.1 36.5 16.5 8.4 56.9 13.6 16.2 11.1 8.6 5.5 8.7 10.5 7.2 44.0 10.5 12.0 4.1 47.7 61.6 13.4 15.8 10.5 12.5 10.4 13.5 40.6 21.4 11.2 6.6 11.6 9.6 8.1 4.4 22.3 5.8 28.3 10.1 24.3 20.5 21.7 MCF2 "ARHGEF21, DBL" ENSG00000101977 "MCF.2 cell line derived transforming sequence" P10911 X 139581770-139708227 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 29.5;seminal vesicle: 17.0;testis: 18.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 98.0;Excitatory neurons: 27.8;Inhibitory neurons: 36.2;Oligodendrocyte precursor cells: 20.6;Theca cells: 22.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "U-251 MG: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.42e-1)" "unprognostic (2.18e-2)" "unprognostic (1.46e-2)" "unprognostic (5.11e-4)" "unprognostic (8.95e-2)" "unprognostic (3.99e-2)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "unprognostic (1.80e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (2.33e-3)" "unprognostic (3.68e-2)" "unprognostic (2.92e-2)" "unprognostic (4.62e-4)" "unprognostic (4.02e-2)" 0.2 29.5 5.8 0.4 4.5 0.7 0.1 6.4 8.8 0.0 1.7 0.1 0.0 0.1 12.3 0.0 0.8 0.7 1.0 4.4 7.0 1.5 0.2 0.1 0.6 9.1 7.4 10.2 0.2 0.0 3.4 0.0 9.7 1.2 0.0 9.2 1.0 17.0 0.1 0.1 0.3 0.0 5.5 1.1 0.2 18.6 14.1 0.5 1.1 0.2 0.1 0.2 0.1 5.9 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.5 3.1 0.0 0.5 0.6 2.5 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.6 37.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 4.5 6.4 8.8 4.4 7.0 9.1 7.4 9.7 5.5 14.1 5.9 0.2 0.0 0.0 3.6 0.3 0.1 0.3 0.2 0.6 2.2 0.6 0.4 1.8 0.0 0.0 0.0 98.0 0.0 0.3 0.1 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.0 27.8 0.0 0.0 0.7 0.0 0.1 0.0 2.2 0.4 0.2 0.1 0.0 36.2 0.0 0.0 0.6 0.3 2.5 1.2 0.2 0.0 4.7 1.4 1.0 4.1 20.6 7.6 0.1 0.0 8.2 0.1 0.4 0.0 0.6 0.0 2.4 0.0 0.1 0.4 0.6 0.8 0.1 0.0 0.0 0.3 22.8 0.0 0.2 MCM10 "CNA43, DNA43, PRO2249" ENSG00000065328 "Minichromosome maintenance 10 replication initiation factor" Q7L590 10 13161558-13211110 "Predicted intracellular proteins" "DNA damage, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.2;lymphoid tissue: 8.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.8;Erythroid cells: 23.5;Extravillous trophoblasts: 20.9;Plasma cells: 15.3;Spermatocytes: 15.8;Spermatogonia: 12.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045899, HPA071952" Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli" "HPA045899: AB_10960529, HPA071952: AB_2686477" "unprognostic (9.76e-3)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-3)" "unprognostic (1.41e-1)" "unprognostic (6.58e-3)" "unprognostic (1.78e-8)" "unprognostic (2.42e-3)" "unprognostic (3.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.78e-4)" "unprognostic (7.81e-2)" "unprognostic (0.00e+0)" "unprognostic (8.87e-2)" "unprognostic (1.29e-1)" "unprognostic (9.73e-2)" "unprognostic (1.05e-1)" 1.2 0.1 0.0 3.3 0.1 9.2 0.8 0.1 0.2 0.4 0.1 1.7 1.5 0.4 0.1 1.9 0.2 0.2 0.1 0.0 0.0 0.1 0.7 0.3 4.8 0.0 0.1 0.2 0.1 0.2 0.1 2.1 0.1 0.1 2.2 0.1 0.3 0.0 0.5 1.1 1.2 0.8 0.0 1.0 0.8 1.5 0.2 8.1 0.3 0.1 4.5 0.6 0.6 0.1 38.0 42.0 48.6 36.9 1.6 2.9 21.2 38.7 5.9 42.7 44.0 41.3 26.4 56.7 17.1 9.9 15.7 43.3 69.0 22.8 39.2 29.7 32.9 70.9 17.6 27.7 0.0 36.6 30.8 0.6 0.8 43.3 4.0 3.5 14.0 45.0 85.2 37.6 23.4 34.0 87.7 15.7 28.9 36.3 10.3 68.3 43.0 34.6 9.8 13.7 9.7 36.6 31.3 22.0 5.9 25.2 27.7 24.9 8.6 27.0 50.3 41.0 42.4 11.7 49.0 74.3 17.2 39.6 21.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.9 0.3 0.1 0.1 0.7 0.4 0.1 0.1 0.0 0.4 0.4 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 1.7 0.0 0.0 0.0 1.8 1.7 0.4 0.8 0.0 0.0 0.8 0.5 2.4 0.0 0.8 0.0 0.0 11.8 0.8 2.4 0.0 0.4 1.0 0.3 1.2 1.4 0.0 23.5 0.4 0.2 20.9 1.8 1.1 1.0 0.0 7.2 0.0 0.2 5.3 0.0 0.4 1.2 2.0 0.6 0.4 1.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.1 0.4 15.3 0.2 0.2 0.0 0.0 0.0 0.0 0.4 6.4 15.8 12.9 3.6 0.4 3.4 1.2 0.8 3.1 0.4 MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.7;lymphoid tissue: 37.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 63.3;Erythroid cells: 65.6;Extravillous trophoblasts: 28.8;Spermatogonia: 25.9;Syncytiotrophoblasts: 33.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 120000 "Cluster 43: B-cells - Humoral immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" 3.1 3.4 2.0 16.4 1.9 67.7 6.2 2.5 1.9 5.3 0.6 9.2 8.1 5.0 2.4 11.0 7.6 2.5 6.4 1.9 1.8 3.4 6.3 3.4 26.8 2.3 1.9 6.4 3.0 3.7 2.4 17.0 2.6 5.0 10.2 3.5 4.7 2.8 9.4 10.6 8.6 5.3 2.0 9.6 5.7 12.3 2.0 37.6 4.8 5.8 26.0 4.2 5.4 2.4 133.6 110.3 122.4 102.1 7.0 14.4 110.5 65.2 42.3 129.9 146.9 177.7 84.7 136.0 65.2 32.3 113.6 105.6 204.8 76.1 79.1 127.2 127.1 227.4 134.8 131.1 4.4 214.3 102.4 8.2 8.4 86.1 13.1 15.3 40.6 160.7 116.0 123.7 47.4 169.0 229.0 156.2 172.5 108.3 90.7 242.4 165.1 203.3 26.9 97.9 143.0 106.8 175.8 48.9 16.7 45.7 111.9 165.3 20.3 104.2 87.9 128.4 91.7 127.1 163.5 362.6 73.2 159.7 41.0 0.0 0.6 0.3 4.4 1.4 5.5 9.7 3.9 5.4 2.9 8.1 3.6 4.7 0.9 6.5 0.4 3.7 11.2 3.5 2.0 1.9 2.5 1.9 1.9 1.8 2.3 1.9 2.6 2.0 2.0 2.4 1.2 3.2 2.0 0.7 8.5 4.6 2.6 4.6 2.2 2.5 4.1 5.3 8.3 0.0 3.9 0.0 0.0 63.3 1.8 4.8 0.0 5.3 0.9 5.2 3.5 2.9 3.6 65.6 0.3 1.9 28.8 4.2 6.6 4.8 1.3 18.8 1.4 1.7 18.2 0.0 0.4 8.2 0.0 1.6 3.2 0.7 1.8 2.7 1.8 0.0 9.2 2.1 0.0 0.0 0.7 2.1 1.7 1.5 20.5 0.8 1.1 0.8 7.4 2.1 0.0 2.6 4.1 8.1 25.9 7.1 3.0 33.5 6.3 3.8 13.8 2.3 MCRIP2 "C16orf14, FAM195A, MGC15416" ENSG00000172366 "MAPK regulated corepressor interacting protein 2" Q9BUT9 16 636817-648474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 48.1;liver: 56.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 189.2;Distal tubular cells: 183.9;Hofbauer cells: 133.9;Proximal tubular cells: 310.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/84: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060363 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA060363: AB_2684263" "unprognostic (7.14e-2)" "unprognostic (3.85e-2)" "unprognostic (8.25e-2)" "unprognostic (2.49e-2)" "unprognostic (2.72e-1)" "unprognostic (4.18e-2)" "unprognostic (1.60e-1)" "unprognostic (2.96e-3)" "unprognostic (7.82e-2)" "unprognostic (3.14e-1)" "unprognostic (2.19e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.06e-2)" "unprognostic (4.00e-2)" "unprognostic (2.10e-2)" "prognostic favorable (7.23e-4)" 9.0 31.4 5.1 2.1 4.8 1.7 5.2 7.0 8.6 4.0 17.3 21.0 6.8 4.0 0.0 8.6 4.3 0.5 48.1 4.8 4.3 25.5 56.1 5.7 0.8 4.6 4.4 4.3 12.5 2.6 12.7 2.2 5.0 8.1 0.9 0.1 8.8 1.5 39.2 2.9 10.7 0.3 3.8 9.5 14.6 5.6 6.3 0.3 7.3 3.3 0.6 9.4 4.3 3.6 14.7 3.4 0.4 6.0 1.3 3.7 7.1 7.8 2.4 3.8 2.1 3.9 6.8 23.9 18.8 0.7 2.2 15.0 2.4 6.0 0.1 19.0 30.4 10.6 3.5 3.1 6.8 18.2 14.4 2.2 5.4 1.7 2.0 1.4 1.3 6.3 23.6 3.0 0.7 4.4 1.7 30.0 9.2 7.5 37.1 25.9 0.1 34.5 3.1 1.1 15.3 7.7 13.9 9.9 26.0 0.3 8.8 14.4 6.1 0.3 7.8 8.6 10.9 37.6 47.0 35.9 1.4 15.8 0.9 0.0 11.3 3.1 1.2 12.9 3.1 10.5 3.3 3.7 10.0 6.8 4.2 2.8 0.2 2.5 14.5 0.3 3.9 3.5 5.1 4.8 7.0 8.6 4.8 4.3 4.6 4.4 5.0 3.8 6.3 3.6 11.3 3.2 12.4 0.0 10.0 0.0 0.0 0.0 0.0 0.0 55.5 53.8 0.0 0.0 1.8 64.4 0.0 189.2 7.9 0.0 183.9 62.7 0.0 17.3 13.1 4.6 0.0 0.0 0.0 70.8 27.6 7.5 0.0 16.9 5.1 51.1 0.0 0.0 133.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 40.3 0.0 0.0 0.0 0.0 67.4 0.0 0.0 1.7 0.0 0.0 310.2 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 79.6 6.3 50.3 0.0 0.0 MCTP1 FLJ22344 ENSG00000175471 "Multiple C2 and transmembrane domain containing 1" Q6DN14 5 94703741-95284575 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 45.3;brain: 37.1" "Cell type enhanced" "Detected in many" "Adipocytes: 113.3;Excitatory neurons: 510.6;Inhibitory neurons: 412.2;Oligodendrocyte precursor cells: 263.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 37.0;classical monocyte: 28.6;eosinophil: 13.2;intermediate monocyte: 41.4;myeloid DC: 22.3;neutrophil: 40.5;non-classical monocyte: 40.6;plasmacytoid DC: 11.4" "Group enriched" "Detected in many" 54 "dendritic cells: 22.3;granulocytes: 40.5;monocytes: 41.4" "Cell line enhanced" "Detected in many" "Karpas-707: 71.4;RPMI-8226: 73.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019018 Approved Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA019018: AB_1853665" "unprognostic (1.20e-2)" "unprognostic (6.70e-4)" "unprognostic (1.77e-2)" "unprognostic (1.03e-2)" "unprognostic (1.16e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (2.47e-2)" "unprognostic (1.86e-1)" "unprognostic (6.99e-2)" "unprognostic (5.31e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-6)" "unprognostic (5.38e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (4.43e-2)" 21.3 2.3 12.8 12.5 37.1 45.3 15.9 27.7 19.4 6.0 0.0 7.7 5.1 5.9 2.0 6.4 4.9 17.4 3.8 20.9 10.0 4.4 3.7 12.9 6.1 3.8 0.5 1.7 3.2 1.9 4.0 7.3 5.7 3.5 7.2 1.7 3.7 2.2 3.2 4.3 4.9 11.2 0.5 8.8 5.5 2.1 1.4 7.9 4.6 7.9 4.4 21.3 6.1 13.4 0.3 5.2 3.3 0.1 49.0 19.6 0.2 0.3 25.1 2.3 8.1 0.1 13.3 18.7 19.2 0.0 51.1 0.2 0.4 0.2 2.8 0.0 3.6 11.4 13.3 0.2 6.4 23.6 14.6 7.3 0.0 9.0 32.5 21.2 52.7 7.6 0.3 71.4 18.7 0.6 1.4 17.9 4.1 0.3 20.7 0.9 0.2 73.7 52.7 29.0 10.0 0.5 1.7 0.1 37.1 1.4 0.0 21.8 0.3 9.0 13.9 0.4 4.2 5.0 0.1 0.2 41.8 38.5 9.1 37.0 28.6 13.2 0.1 41.4 0.0 0.6 0.1 0.2 22.3 0.3 0.4 0.0 40.5 0.3 40.6 11.4 0.0 8.5 12.8 37.1 27.7 19.4 20.9 10.0 3.8 0.5 5.7 0.5 1.4 13.4 113.3 3.2 10.8 15.3 3.2 18.1 0.2 6.9 3.4 2.2 1.7 1.1 3.1 0.0 6.6 3.7 0.0 0.3 9.8 0.1 0.0 0.0 27.8 5.5 1.2 97.9 0.0 5.0 510.6 0.2 0.2 18.5 5.6 11.6 63.3 0.1 2.2 0.3 12.2 3.3 412.2 0.0 4.1 42.4 76.5 16.2 0.6 63.5 12.4 67.5 32.9 3.2 2.1 263.4 9.0 1.3 0.0 0.0 2.4 0.8 0.0 0.5 3.5 3.5 0.0 1.8 2.0 1.8 1.4 0.7 13.4 0.3 3.7 0.3 0.0 0.6 MCUR1 "C6orf79, CCDC90A, FLJ20958" ENSG00000050393 "Mitochondrial calcium uniporter regulator 1" Q96AQ8 6 13786557-13814568 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 81.6" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 238.5;Rod photoreceptor cells: 293.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078654 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA078654: " "unprognostic (1.82e-3)" "unprognostic (1.58e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-3)" "unprognostic (8.62e-2)" "unprognostic (2.25e-3)" "unprognostic (2.01e-3)" "unprognostic (2.16e-1)" "unprognostic (4.83e-2)" "prognostic favorable (5.51e-4)" "unprognostic (3.40e-1)" "unprognostic (5.77e-2)" "prognostic favorable (3.32e-4)" "unprognostic (5.86e-2)" "unprognostic (2.68e-1)" "unprognostic (4.05e-2)" "unprognostic (2.39e-1)" 9.7 5.4 20.2 7.2 21.0 7.1 10.0 19.6 32.6 7.8 18.5 10.8 19.1 7.0 13.1 10.0 4.6 5.5 12.2 20.9 21.3 22.6 9.2 8.6 6.6 21.0 20.8 3.9 12.6 9.0 5.9 8.7 22.0 6.4 9.7 81.6 9.1 7.6 19.3 18.3 16.5 5.1 20.0 7.6 6.4 4.8 22.5 8.1 16.0 15.8 9.4 6.2 7.7 19.7 23.4 6.9 34.4 34.6 19.8 17.0 21.8 21.0 19.9 22.4 23.4 24.0 11.3 31.6 41.0 15.1 35.2 10.2 21.5 17.7 25.4 21.2 13.1 32.3 12.2 24.0 19.4 32.4 12.6 11.9 16.9 29.1 20.9 16.7 8.1 38.7 24.4 16.3 15.8 9.7 40.1 49.0 22.2 59.9 9.0 29.2 30.3 45.2 27.4 14.2 22.0 24.9 14.0 35.4 58.1 53.1 13.2 14.6 11.5 33.5 18.8 24.2 29.3 20.0 71.9 45.4 15.6 19.0 46.4 4.2 1.3 0.3 1.5 1.2 1.8 1.9 2.1 2.2 3.2 1.7 1.6 1.5 0.8 1.7 1.7 2.0 1.3 2.9 20.2 21.0 19.6 32.6 20.9 21.3 21.0 20.8 22.0 20.0 22.5 19.7 40.5 16.0 25.0 13.1 33.2 44.7 24.2 16.9 39.3 48.0 62.8 54.1 43.6 28.6 15.1 57.0 120.9 45.3 27.2 75.0 138.9 27.4 48.9 29.3 83.5 38.7 15.6 62.9 16.7 31.7 66.9 30.5 7.1 31.3 7.0 16.7 28.2 72.4 91.6 26.9 11.5 49.6 24.4 34.7 80.2 6.8 22.1 60.1 51.6 10.3 36.6 50.4 25.7 7.5 13.4 29.2 91.3 27.1 80.7 60.2 161.6 238.5 11.2 293.7 19.7 20.7 34.5 13.1 52.4 47.3 57.4 86.2 21.0 31.0 37.5 31.1 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MECR "CGI-63, ETR1, FASN2B, NRBF1" ENSG00000116353 "Mitochondrial trans-2-enoyl-CoA reductase" Q9BV79 1 29192657-29230942 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.1" "Cell type enhanced" "Detected in all" "Late spermatids: 82.5;Rod photoreceptor cells: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022018, HPA022030, HPA028740" Enhanced Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA022018: AB_1853714, HPA022030: AB_1853716, HPA028740: AB_10601133" "unprognostic (2.53e-1)" "unprognostic (1.09e-2)" "unprognostic (1.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.07e-1)" "unprognostic (2.46e-1)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-1)" "unprognostic (3.06e-2)" "unprognostic (8.66e-2)" "prognostic favorable (5.81e-6)" "unprognostic (7.01e-3)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "prognostic unfavorable (5.29e-4)" 14.7 14.6 5.1 1.7 5.1 1.8 13.4 3.3 6.2 10.2 3.1 10.3 1.4 12.9 2.5 12.5 9.4 1.3 24.8 6.0 3.9 14.1 15.8 7.3 2.0 5.2 4.0 10.0 8.9 4.5 7.2 3.5 5.4 7.9 2.6 9.9 12.3 3.0 42.1 15.4 7.2 3.1 3.2 6.7 11.1 7.6 4.3 1.4 8.3 5.8 2.1 9.6 9.6 5.2 3.9 4.5 3.2 4.6 2.9 2.5 6.8 3.7 3.8 4.7 3.9 2.3 5.6 7.3 5.1 3.7 1.3 3.0 5.4 6.3 4.0 4.4 6.9 6.4 3.4 4.1 6.6 6.1 1.9 4.3 5.9 3.1 11.0 3.8 3.5 6.9 5.8 4.2 4.7 4.5 3.9 2.9 6.5 5.8 4.3 3.5 4.2 9.3 5.9 2.4 5.1 4.5 4.1 4.7 7.0 4.4 2.3 5.4 3.8 2.4 2.9 4.1 4.7 2.7 2.2 5.0 3.9 8.4 5.2 0.1 2.2 0.0 1.5 2.1 4.1 2.2 1.6 1.7 1.9 1.1 2.3 1.6 0.3 2.9 1.6 2.5 2.4 1.2 5.1 5.1 3.3 6.2 6.0 3.9 5.2 4.0 5.4 3.2 4.3 5.2 8.8 12.8 3.9 14.7 9.1 5.6 15.6 26.9 7.4 12.8 12.0 14.6 19.8 21.5 21.4 20.2 10.4 46.0 3.8 7.4 41.1 24.3 40.8 19.7 13.6 9.1 7.8 10.1 25.1 19.7 42.4 12.8 4.6 12.8 5.7 17.5 7.1 19.7 20.8 8.4 20.3 9.4 12.2 6.0 5.1 82.5 13.7 5.3 16.0 3.7 10.8 14.5 10.3 11.6 15.2 16.3 8.0 10.9 10.3 20.6 10.9 46.0 11.3 68.5 13.1 13.2 12.9 8.5 16.1 14.0 7.4 27.9 6.0 25.8 18.3 20.5 MED26 "CRSP7, CRSP70" ENSG00000105085 "Mediator complex subunit 26" O95402 19 16574907-16629062 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.9" "Cell type enhanced" "Detected in many" "Early spermatids: 65.4;Late spermatids: 67.4;Spermatocytes: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057997, HPA071835" Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA057997: AB_2732618, HPA071835: AB_2686455" "unprognostic (2.02e-2)" "prognostic favorable (2.46e-4)" "unprognostic (2.47e-2)" "unprognostic (2.57e-3)" "unprognostic (1.42e-1)" "unprognostic (3.60e-3)" "unprognostic (5.03e-2)" "unprognostic (3.77e-2)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.99e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (5.50e-5)" "unprognostic (9.43e-3)" "unprognostic (1.64e-1)" "unprognostic (5.14e-2)" "unprognostic (5.98e-3)" 4.5 3.8 4.4 3.8 4.0 11.0 4.1 5.1 4.7 4.0 4.0 4.1 2.4 4.3 1.8 5.2 3.2 2.3 3.2 5.0 5.1 2.8 3.7 4.0 4.9 5.2 4.7 4.7 3.9 3.5 3.6 3.2 4.7 4.2 1.9 2.0 4.5 2.4 6.9 6.4 3.6 2.5 3.6 4.7 3.6 35.9 4.5 4.4 3.1 3.2 4.6 3.9 4.6 4.2 11.1 4.2 3.8 8.3 4.8 3.8 11.1 6.3 4.4 6.7 6.0 6.3 6.5 17.6 6.5 4.0 2.1 8.2 5.9 6.3 4.6 13.0 12.2 6.9 4.2 5.1 4.7 7.9 6.3 4.6 6.1 5.7 5.9 4.0 3.6 9.1 11.5 20.7 4.2 11.1 8.4 7.4 9.0 5.2 13.4 8.7 5.8 19.3 4.0 4.3 10.0 5.4 5.5 5.3 6.4 2.7 3.9 10.3 4.5 8.5 6.8 10.4 8.5 14.3 12.6 14.4 6.0 10.4 5.0 0.7 0.1 0.1 0.5 0.3 0.1 0.4 0.0 0.2 0.2 0.7 0.3 0.0 0.3 0.4 0.1 1.4 0.7 0.1 4.4 4.0 5.1 4.7 5.0 5.1 5.2 4.7 4.7 3.6 4.5 4.2 13.7 3.2 12.7 11.4 11.8 14.1 5.0 3.8 11.4 4.2 14.3 12.2 1.1 2.8 3.0 5.5 10.4 6.2 15.8 5.9 3.9 4.4 65.4 12.9 7.7 6.1 2.4 5.0 8.6 4.0 11.1 7.0 5.6 16.6 1.3 5.8 4.2 5.6 5.0 5.0 7.6 4.7 2.0 8.5 10.7 67.4 6.5 9.9 1.8 1.9 4.9 6.0 4.1 7.1 8.5 6.0 3.0 3.8 15.9 6.7 3.6 2.0 3.5 6.4 0.0 17.7 8.0 54.1 19.4 11.5 10.7 16.8 11.0 6.1 5.1 8.7 MEF2A "RSRFC4, RSRFC9" ENSG00000068305 "Myocyte enhancer factor 2A" Q02078 15 99565417-99716466 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 262.8;Microglial cells: 708.3;Oligodendrocytes: 264.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004499, HPA046597" Approved Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004499: AB_627921, HPA046597: AB_2679714" "unprognostic (1.89e-1)" "unprognostic (8.82e-2)" "unprognostic (5.91e-2)" "unprognostic (8.04e-2)" "unprognostic (8.68e-2)" "unprognostic (2.05e-1)" "unprognostic (2.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.93e-2)" "unprognostic (1.91e-2)" "unprognostic (7.08e-3)" "unprognostic (1.46e-1)" "prognostic favorable (6.93e-4)" "prognostic unfavorable (7.96e-4)" "unprognostic (4.69e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-3)" 32.8 22.9 18.7 20.3 25.4 18.3 22.1 16.4 27.6 27.7 12.9 23.5 12.8 34.5 23.8 21.7 21.8 22.6 89.7 21.9 12.1 24.8 24.5 30.4 25.0 17.4 20.7 30.1 12.8 37.6 9.8 26.4 15.4 23.0 15.0 24.2 19.5 23.7 61.5 54.8 17.6 35.7 18.4 27.2 17.8 15.0 28.4 23.3 19.7 81.9 22.9 22.5 16.6 25.7 17.9 10.1 16.7 8.5 20.7 26.3 8.2 17.8 40.8 14.4 19.5 10.4 24.4 22.3 24.5 38.6 22.1 19.3 17.1 14.1 18.6 15.3 24.8 45.2 22.3 9.4 35.4 18.1 21.3 17.6 23.2 19.3 39.7 59.6 26.5 18.3 16.3 41.6 27.0 7.4 29.7 26.3 8.9 11.9 14.6 43.3 36.1 18.5 29.5 24.9 10.7 14.8 27.2 11.6 51.0 17.6 11.0 16.4 43.7 39.8 21.9 19.9 21.7 22.6 27.8 48.5 27.8 19.6 38.7 7.7 12.1 14.3 3.9 15.6 3.3 15.8 3.6 3.6 13.3 12.1 5.0 3.9 10.8 6.5 19.3 7.8 2.6 5.6 18.7 25.4 16.4 27.6 21.9 12.1 17.4 20.7 15.4 18.4 28.4 25.7 152.7 80.1 43.9 113.9 87.2 88.6 31.7 26.9 62.0 52.0 31.6 37.0 175.8 20.0 40.7 29.5 50.1 7.7 32.9 26.5 25.4 18.0 10.4 80.3 60.6 100.6 12.7 24.8 262.8 18.8 3.4 61.5 34.7 130.7 31.0 30.5 50.3 41.0 39.5 30.3 174.9 17.2 12.2 107.5 63.1 7.8 55.9 104.1 35.6 708.3 65.8 25.2 23.7 157.3 264.4 26.8 22.6 64.7 55.6 27.0 18.9 19.7 51.7 44.9 72.3 62.4 69.4 29.9 29.6 29.4 50.4 9.2 27.8 28.8 17.9 26.8 MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 471.5;Excitatory neurons: 735.7;Inhibitory neurons: 759.5;Microglial cells: 730.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Cell line enhanced" "Detected in many" "Daudi: 103.6;HEL: 229.3;Karpas-707: 121.6;REH: 261.8;WM-115: 145.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" 28.9 26.8 29.7 39.2 58.6 11.1 17.5 0.0 75.3 18.8 0.0 15.9 6.9 25.9 7.3 13.6 17.3 28.5 35.2 55.7 0.0 10.4 10.5 21.3 62.9 0.0 0.0 34.9 5.6 9.3 6.3 45.5 0.0 20.0 15.4 34.2 9.0 17.7 555.4 4.9 11.2 31.5 0.0 43.8 12.7 9.4 0.0 12.8 21.7 246.8 77.7 21.3 7.6 11.0 1.6 0.0 7.1 0.0 7.7 4.6 0.2 2.2 4.5 0.3 1.0 0.2 1.0 103.6 0.6 12.0 2.5 3.1 9.6 9.1 0.2 31.7 12.5 229.3 12.3 0.0 2.8 10.4 0.6 21.6 0.0 0.3 0.0 1.4 35.1 0.0 12.3 121.6 9.0 0.0 0.3 0.1 2.2 0.1 8.4 261.8 63.1 50.5 0.0 1.2 0.0 8.3 0.0 0.7 29.5 3.9 0.3 58.0 40.4 5.6 1.0 0.6 5.4 92.0 11.5 62.0 1.5 70.1 145.2 0.6 72.0 0.2 0.2 82.6 0.1 141.6 0.2 0.1 95.2 187.9 0.2 0.2 24.3 16.7 71.5 100.3 0.5 34.4 29.7 58.6 0.0 75.3 55.7 0.0 0.0 0.0 0.0 0.0 0.0 11.0 367.4 32.1 52.0 117.5 471.5 10.7 4.2 0.0 7.4 22.6 5.2 26.5 86.4 10.0 21.7 1.8 214.8 0.8 138.6 9.2 27.4 0.8 11.0 0.8 13.4 197.5 1.2 59.1 735.7 12.7 1.2 26.8 2.0 1.0 5.1 107.5 283.4 3.4 171.1 5.0 759.5 1.5 0.0 205.8 127.5 8.6 29.8 205.1 67.6 730.7 202.7 61.8 8.2 119.6 18.7 0.4 3.0 71.8 314.7 2.1 0.2 0.8 3.7 202.9 335.2 72.7 257.6 4.0 29.5 2.5 8.4 1.6 12.2 58.6 6.3 2.3 MEFV "FMF, MEF, TRIM20" ENSG00000103313 "MEFV innate immuity regulator, pyrin" O15553 16 3242027-3256633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" Actin-binding "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 7.6;Kupffer cells: 15.1;Macrophages: 15.5;monocytes: 26.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 8.3" "Group enriched" "Detected in many" 4 "granulocytes: 8.3;monocytes: 5.7" "Cell line enriched" "Detected in some" 6 "THP-1: 6.6" "Not detected" "Not detected" HPA077497 Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA077497: " "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (4.96e-2)" "unprognostic (2.01e-1)" "unprognostic (2.49e-2)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "unprognostic (3.35e-2)" "unprognostic (2.97e-2)" "unprognostic (1.09e-1)" "unprognostic (8.89e-2)" "unprognostic (3.27e-1)" "unprognostic (7.58e-7)" "unprognostic (1.08e-1)" "unprognostic (7.16e-4)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" 2.4 0.6 0.1 6.5 0.2 6.1 0.3 0.4 1.0 0.2 0.3 0.4 0.5 0.2 0.2 0.3 0.6 1.0 0.5 0.3 0.1 0.4 0.7 4.0 0.4 0.3 0.2 0.1 0.2 0.0 0.2 0.8 0.5 0.2 0.3 0.2 0.3 0.0 0.7 0.2 0.6 1.0 0.0 8.9 0.4 1.3 0.3 0.4 0.3 0.3 0.3 1.8 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 1.1 0.0 2.4 3.2 0.1 0.0 3.4 0.0 0.1 0.1 0.0 1.7 0.2 0.0 0.1 8.3 0.3 5.7 0.1 0.0 1.2 0.1 0.2 0.4 1.0 0.3 0.1 0.3 0.2 0.5 0.0 0.3 0.4 0.2 0.0 1.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 7.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.4 0.2 1.0 0.0 0.1 0.0 0.0 15.1 2.4 0.3 0.0 15.5 0.0 0.0 26.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.2 0.3 0.7 0.0 0.1 0.0 0.6 0.0 0.0 0.1 MEGF10 "KIAA1780, SR-F3" ENSG00000145794 "Multiple EGF like domains 10" Q96KG7 5 127290796-127465737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis, Phagocytosis" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 52.6" "Cell type enhanced" "Detected in some" "Astrocytes: 218.4;Oligodendrocyte precursor cells: 97.5;Oligodendrocytes: 381.7;Skeletal myocytes: 62.9" "Cancer enhanced" "Detected in some" "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 31.6;RH-30: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 73000000 "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (7.02e-2)" "unprognostic (4.50e-2)" "unprognostic (1.02e-1)" "unprognostic (2.26e-3)" "unprognostic (8.91e-3)" "unprognostic (1.59e-2)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.41e-1)" "unprognostic (1.76e-4)" "unprognostic (5.28e-3)" "unprognostic (2.59e-1)" "unprognostic (9.36e-4)" "unprognostic (1.17e-1)" 0.2 1.7 18.0 0.1 34.9 0.0 0.7 29.4 19.9 0.3 0.0 0.8 0.1 0.7 0.4 0.1 0.1 0.0 0.4 15.6 18.2 0.0 0.4 0.0 0.0 26.6 26.8 0.1 0.0 0.0 1.7 0.1 29.4 0.7 0.2 8.0 1.9 1.1 3.0 0.3 0.2 0.3 21.2 0.1 0.1 0.4 23.8 0.6 0.1 4.8 0.2 0.0 0.1 52.6 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 6.8 0.0 0.2 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.0 3.4 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.7 0.0 0.1 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 34.9 29.4 19.9 15.6 18.2 26.6 26.8 29.4 21.2 23.8 52.6 0.0 0.0 0.0 218.4 0.0 0.0 0.1 0.0 0.0 2.0 0.7 1.5 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 6.5 1.3 0.2 0.0 0.0 4.5 0.0 0.0 0.4 0.0 15.4 0.0 0.7 0.0 0.2 0.0 8.4 3.5 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 29.0 0.0 38.9 1.0 97.5 381.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 2.0 0.0 62.9 0.2 0.4 0.7 0.0 0.1 0.0 0.1 5.1 0.0 0.1 MEI4 ENSG00000269964 "Meiotic double-stranded break formation protein 4" A8MW99 6 77650274-77927028 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 4.0;testis: 3.7;thyroid gland: 2.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 86.1" "Cancer enhanced" "Detected in some" "renal cancer: 0.9;testis cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 43: Testis - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.47e-1)" "unprognostic (9.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (1.88e-1)" "unprognostic (4.62e-2)" "unprognostic (9.70e-4)" "unprognostic (3.16e-1)" "unprognostic (2.86e-4)" "unprognostic (3.35e-2)" "unprognostic (4.17e-2)" "unprognostic (4.85e-2)" 0.1 0.7 0.4 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.2 0.6 4.0 0.8 0.0 0.0 1.0 0.5 0.0 2.0 0.1 1.0 0.0 1.2 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 3.7 0.6 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.2 0.2 0.6 1.0 0.5 1.2 0.5 0.6 0.6 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 86.1 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 21.3 0.3 0.0 0.0 9.4 0.0 0.6 0.0 2.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 21.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.1;Erythroid cells: 15.2;Extravillous trophoblasts: 44.1;Spermatocytes: 23.2;Spermatogonia: 21.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "T-reg: 1.7" "Lineage enriched" "Detected in single" 4 "T-cells: 1.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017214 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.91e-7)" "prognostic unfavorable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 0.9 0.5 0.0 5.7 0.0 10.0 1.4 0.0 0.1 1.3 0.0 6.8 5.2 1.0 0.0 7.9 0.3 0.6 0.2 0.0 0.0 0.3 0.7 0.9 10.0 0.0 0.1 0.2 0.3 0.1 0.0 5.3 0.1 0.3 8.5 0.0 1.2 0.1 0.0 3.4 4.4 2.4 0.0 2.0 3.2 9.2 0.3 21.0 0.3 0.1 11.7 1.7 2.3 0.0 123.4 62.1 81.6 48.5 11.1 18.8 47.1 88.8 62.2 121.5 148.2 47.8 47.3 40.9 27.8 43.8 106.5 41.0 71.7 55.5 133.1 112.3 28.6 32.0 69.1 48.1 4.3 50.2 39.0 6.9 9.8 93.9 53.0 15.6 62.2 61.9 41.7 63.2 100.9 40.9 63.1 23.4 65.1 55.1 47.9 57.4 54.9 25.8 37.7 40.7 55.1 40.8 47.4 45.3 28.6 45.2 38.0 23.7 30.8 65.4 81.8 56.1 82.3 12.3 47.9 60.7 41.2 36.8 91.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 1.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.7 1.9 4.6 0.9 3.5 0.0 0.0 0.9 0.8 0.4 0.0 2.0 0.0 0.0 16.1 0.7 4.5 0.0 1.1 2.8 2.9 1.4 1.3 0.0 15.2 0.8 1.1 44.1 3.3 4.6 2.1 0.0 7.8 1.4 0.7 10.1 0.0 0.7 4.7 4.1 1.6 3.0 2.7 1.2 1.9 0.0 0.0 3.1 0.0 2.1 1.0 0.4 1.7 2.7 0.0 10.2 0.5 0.6 0.1 2.0 0.0 0.0 0.0 3.7 23.2 21.3 9.3 1.7 8.9 2.7 0.7 8.9 2.3 MELTF "CD228, FLJ38863, MAP97, MFI2, MGC4856, MTf, MTF1" ENSG00000163975 Melanotransferrin P08582 3 196988621-197029817 "CD markers, Plasma proteins, Predicted intracellular proteins" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 35.1;salivary gland: 68.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 21.1;Breast myoepithelial cells: 20.6;Collecting duct cells: 14.7;Ductal cells: 28.3;Hofbauer cells: 15.4;Pancreatic endocrine cells: 66.4" "Cancer enhanced" "Detected in all" "melanoma: 32.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 162.1;SK-MEL-30: 201.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004880 Approved "Intracellular and membrane" NA NA 41000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA004880: AB_1853844" "unprognostic (8.68e-3)" "unprognostic (3.68e-2)" "unprognostic (1.75e-2)" "unprognostic (7.68e-3)" "unprognostic (1.06e-2)" "unprognostic (1.08e-2)" "unprognostic (5.53e-2)" "unprognostic (1.64e-3)" "unprognostic (1.20e-2)" "unprognostic (1.23e-1)" "unprognostic (3.68e-3)" "unprognostic (8.14e-2)" "prognostic unfavorable (6.99e-11)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "unprognostic (5.75e-2)" "unprognostic (2.09e-2)" 10.0 1.7 2.3 3.8 1.7 2.3 7.4 2.1 3.8 8.1 27.2 4.0 2.4 6.8 0.7 2.9 8.6 1.6 7.5 2.5 1.9 35.1 1.6 1.9 1.9 0.6 2.8 1.2 4.6 10.3 2.9 1.5 0.4 4.1 2.1 0.3 68.7 5.5 1.1 16.4 9.9 1.2 0.5 1.1 1.7 3.4 6.5 2.9 3.1 1.0 1.6 3.2 7.3 2.0 162.1 34.6 0.4 1.2 4.8 6.0 4.0 2.8 1.5 5.2 6.3 9.8 23.6 4.5 33.3 5.6 4.5 49.6 1.8 0.1 2.3 7.4 10.8 5.6 7.9 4.1 30.5 0.8 30.8 33.0 4.3 4.3 0.4 0.2 0.8 8.9 4.3 30.5 3.1 9.8 9.3 0.0 3.6 6.9 22.5 13.4 5.3 2.0 0.8 1.5 3.1 11.3 32.5 2.8 201.4 3.8 9.5 4.8 1.2 1.2 26.8 5.5 19.9 5.3 46.0 4.5 3.9 9.5 0.2 0.0 0.1 0.0 0.2 0.2 0.8 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.2 2.3 1.7 2.1 3.8 2.5 1.9 0.6 2.8 0.4 0.5 6.5 2.0 0.8 0.0 1.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 21.1 20.6 0.0 0.0 1.8 14.7 0.0 0.2 1.0 0.0 0.0 28.3 0.0 3.2 6.1 0.6 0.0 0.0 0.0 5.7 0.3 3.7 0.0 4.4 0.0 3.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 2.6 0.0 0.0 0.0 0.0 66.4 0.0 0.0 1.7 0.0 0.0 0.5 1.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.0 METTL7B "ALDI, MGC17301" ENSG00000170439 "Methyltransferase like 7B" Q6UX53 12 55681678-55684611 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 133.1;heart muscle: 124.2;liver: 284.3" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.9;Hofbauer cells: 72.7;Proximal enterocytes: 192.4;Proximal tubular cells: 55.6" "Cancer enhanced" "Detected in many" "glioma: 97.9;liver cancer: 97.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 4.5;myeloid DC: 7.0;naive B-cell: 1.7;non-classical monocyte: 3.3" "Group enriched" "Detected in many" 45 "B-cells: 1.7;dendritic cells: 7.0;monocytes: 4.5" "Cell line enhanced" "Detected in many" "CACO-2: 28.4;CAPAN-2: 56.6;EFO-21: 41.3;Hep G2: 28.7;LHCN-M2: 47.0;OE19: 32.5;THP-1: 42.2;U-87 MG: 41.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038644 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Microtubules Vesicles "HPA038644: AB_2676130" "unprognostic (7.54e-2)" "unprognostic (7.15e-2)" "unprognostic (5.55e-2)" "unprognostic (3.07e-3)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-2)" "unprognostic (5.33e-2)" "unprognostic (2.64e-1)" "unprognostic (2.76e-2)" "unprognostic (7.10e-2)" "prognostic favorable (2.37e-4)" "unprognostic (2.43e-1)" 2.1 1.7 5.5 1.8 5.9 1.2 0.9 4.9 10.8 0.4 5.9 28.5 59.6 0.4 133.1 0.1 3.1 11.7 124.2 13.1 5.9 52.1 284.3 1.6 2.3 8.4 5.5 0.1 2.9 0.2 3.1 10.9 5.0 0.3 23.6 1.3 0.5 0.8 7.4 0.9 55.3 2.1 5.7 4.3 4.2 0.7 11.6 0.2 3.3 10.0 0.5 1.3 0.1 7.7 0.4 21.8 0.1 0.5 4.3 15.3 0.3 0.8 3.2 0.2 1.4 28.4 56.6 11.6 41.3 1.2 1.1 0.1 4.1 0.3 0.8 0.0 5.4 1.2 3.2 28.7 0.0 0.6 0.0 4.0 0.0 1.0 0.0 4.2 0.0 0.0 0.2 0.0 47.0 20.2 0.0 0.4 5.7 32.5 2.7 0.0 1.5 2.7 0.5 0.1 0.1 0.3 2.2 0.0 3.9 0.2 3.8 42.2 0.0 3.1 3.5 0.4 2.9 0.0 0.6 3.5 41.9 9.9 0.2 0.0 0.8 0.0 0.0 4.5 0.0 0.5 0.0 0.0 7.0 1.7 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.4 5.5 5.9 4.9 10.8 13.1 5.9 8.4 5.5 5.0 5.7 11.6 7.7 0.0 0.0 1.5 0.7 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.1 26.5 22.8 0.6 0.0 0.0 0.5 0.0 29.0 3.9 3.9 0.0 0.1 0.0 0.5 1.2 4.0 0.7 5.1 0.5 2.0 2.6 0.2 0.0 0.8 1.1 83.9 72.7 0.0 0.1 14.0 0.0 17.0 0.0 0.0 0.0 3.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 4.6 20.7 1.2 0.0 0.1 192.4 55.6 0.0 0.0 0.0 7.8 0.6 0.0 0.1 0.0 0.0 0.7 0.3 0.1 22.2 0.1 MFAP1 AMP ENSG00000140259 "Microfibril associated protein 1" P55081 15 43804492-43824690 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015583, HPA042370" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Centrosome "HPA015583: , HPA042370: AB_10796904" "unprognostic (1.05e-1)" "unprognostic (5.94e-2)" "unprognostic (2.56e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (5.28e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.08e-1)" "unprognostic (1.48e-1)" "unprognostic (1.66e-2)" "unprognostic (3.12e-1)" "unprognostic (7.02e-2)" "prognostic favorable (1.04e-9)" "unprognostic (1.66e-2)" "unprognostic (9.68e-2)" "unprognostic (3.82e-3)" "unprognostic (1.54e-2)" 15.9 24.0 17.5 17.6 18.0 12.9 21.4 21.3 23.2 16.6 19.7 17.1 14.5 18.8 23.4 22.2 18.4 14.9 22.1 17.7 19.3 23.7 18.1 15.2 26.6 18.3 19.3 24.8 15.3 33.2 14.5 23.2 18.7 22.8 18.1 25.0 17.0 17.7 26.3 20.5 15.0 19.1 17.7 17.1 16.8 19.3 18.5 24.4 24.7 23.2 32.4 20.6 17.5 19.1 40.1 41.0 69.4 46.0 57.9 36.3 42.7 63.1 43.8 50.3 58.2 64.1 25.6 42.8 58.7 39.4 50.9 70.8 62.5 51.7 58.9 72.9 37.6 103.7 71.6 48.5 45.4 62.3 53.2 34.1 55.3 48.0 43.3 48.0 49.8 48.3 95.8 35.7 60.9 30.0 51.1 47.0 49.2 74.2 35.4 73.9 69.6 27.6 52.0 59.0 43.8 43.0 55.6 47.0 27.0 55.2 70.7 39.5 47.4 50.6 35.8 56.3 51.7 43.5 112.2 91.8 42.5 58.4 37.9 42.5 25.5 56.9 35.3 34.8 34.7 35.0 35.1 33.6 32.6 28.3 35.7 35.0 22.6 50.5 29.1 26.8 44.1 26.3 17.5 18.0 21.3 23.2 17.7 19.3 18.3 19.3 18.7 17.7 18.5 19.1 30.4 35.3 30.2 5.2 32.8 30.3 59.6 50.1 35.9 41.8 22.4 28.8 31.0 25.8 43.2 51.5 6.2 94.6 33.2 27.4 56.7 44.2 6.2 43.1 39.9 35.6 11.3 32.0 9.0 29.4 55.0 29.8 21.4 39.4 46.3 37.6 20.7 18.8 35.4 32.0 8.6 24.4 38.7 20.7 20.5 6.3 28.0 25.5 26.6 5.6 30.6 51.5 33.0 2.0 8.2 26.8 27.1 35.7 20.6 39.3 22.1 42.9 60.0 35.2 19.7 35.9 41.7 49.7 84.8 28.1 27.7 147.4 33.6 39.4 21.3 50.6 MFAP5 "MAGP2, MP25" ENSG00000197614 "Microfibril associated protein 5" Q13361 12 8637346-8662888 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 242.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.5;Extravillous trophoblasts: 1015.1;Fibroblasts: 579.7;Syncytiotrophoblasts: 252.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 31.7" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 172.2;BJ: 63.7;EFO-21: 150.4;HeLa: 55.9;SuSa: 137.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 42.6" HPA010553 Enhanced "Secreted to extracellular matrix" NA NA 3200000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA010553: AB_1853843" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (4.25e-2)" "unprognostic (4.84e-2)" "unprognostic (1.44e-1)" "unprognostic (6.05e-2)" "unprognostic (2.15e-3)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (8.79e-2)" "unprognostic (8.63e-3)" "unprognostic (3.05e-1)" "unprognostic (4.41e-7)" "prognostic unfavorable (6.87e-4)" "unprognostic (8.81e-2)" "unprognostic (2.05e-2)" "prognostic unfavorable (5.81e-4)" 141.7 10.9 3.5 5.4 5.0 3.5 79.7 31.7 9.2 59.9 1.8 37.8 7.2 242.1 11.1 35.0 25.8 28.2 54.4 4.8 0.8 3.1 12.7 8.7 4.8 2.9 0.4 2.4 5.5 2.4 3.7 94.5 1.9 6.4 42.0 7.9 17.2 49.7 28.5 38.7 19.0 142.1 0.0 1.9 23.6 6.9 1.7 3.2 14.4 118.1 3.4 43.1 60.7 6.6 1.4 5.7 1.6 2.6 29.4 12.4 172.2 63.7 1.2 0.8 1.1 2.3 1.0 0.6 150.4 19.8 1.6 9.1 0.6 13.1 0.0 0.5 0.4 1.6 55.9 1.9 0.4 1.3 0.6 8.7 4.4 7.3 0.0 3.3 0.0 2.0 2.7 3.7 52.7 0.8 1.9 0.8 3.2 0.9 2.9 1.2 1.3 6.5 6.5 2.6 0.7 0.9 1.9 0.7 1.0 137.1 24.0 0.8 2.3 10.7 21.5 45.7 3.0 2.1 1.9 2.3 6.0 0.7 0.1 2.9 0.8 0.7 0.2 0.7 0.4 0.1 0.1 0.1 0.4 0.3 0.4 0.1 1.1 0.2 0.5 0.3 0.0 0.3 3.5 5.0 31.7 9.2 4.8 0.8 2.9 0.4 1.9 0.0 1.7 6.6 61.5 12.8 5.8 0.3 0.5 23.1 0.4 1.8 0.6 0.2 0.6 0.9 7.0 0.0 2.0 0.0 0.0 140.5 0.5 0.0 0.0 0.5 0.3 5.1 3.9 20.1 0.0 0.0 0.2 0.0 1015.1 579.7 3.6 28.0 0.0 0.2 4.2 0.0 27.7 0.0 0.1 0.0 0.0 9.5 36.3 0.5 61.2 8.8 12.4 0.0 0.1 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.6 0.1 0.0 0.2 1.6 0.9 0.0 40.2 35.2 0.1 0.2 0.6 18.0 252.3 5.3 0.1 0.0 0.3 MFSD2A "FLJ14490, MFSD2" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 96.9;liver: 162.0;skin 1: 87.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 136.2;Hepatocytes: 299.6;Proximal enterocytes: 235.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 12 "dendritic cells: 24.3;monocytes: 13.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 52.0;THP-1: 169.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" 6.3 1.4 34.0 3.4 31.7 8.4 13.4 34.8 36.0 4.8 22.2 7.2 14.6 8.5 96.9 12.5 3.5 2.3 1.4 30.9 33.4 5.8 162.0 36.1 2.3 38.5 33.8 2.2 0.6 0.7 8.0 17.1 38.6 2.4 5.0 2.6 4.0 79.2 0.5 87.8 32.0 3.5 32.8 1.5 1.9 33.9 37.2 1.6 7.5 0.1 3.6 20.2 14.1 33.1 6.2 2.7 12.5 18.9 8.7 1.6 0.0 5.9 11.2 12.8 15.1 0.8 3.4 38.0 3.4 3.0 8.8 15.0 12.4 21.8 9.8 4.9 6.0 4.6 0.1 0.1 28.8 6.8 21.8 9.7 13.3 52.0 21.5 2.3 3.1 11.5 0.0 9.5 5.7 0.8 10.6 10.4 10.1 21.4 4.7 7.4 18.5 8.7 2.1 17.9 4.4 6.7 4.5 31.7 3.0 1.1 1.5 169.8 2.0 2.7 5.3 9.5 24.9 1.8 3.5 8.5 28.9 26.0 9.2 0.0 13.2 1.4 0.1 6.6 0.2 1.5 0.1 0.2 14.7 0.2 0.0 0.1 0.7 0.2 1.2 24.3 0.0 3.6 34.0 31.7 34.8 36.0 30.9 33.4 38.5 33.8 38.6 32.8 37.2 33.1 0.5 19.2 136.2 3.3 6.3 52.8 21.2 40.0 51.2 2.0 6.3 2.3 0.6 12.8 30.8 16.5 0.0 0.5 5.7 62.2 0.0 3.4 1.0 25.8 5.5 22.9 1.2 5.7 1.5 24.8 7.6 9.7 24.5 61.8 17.2 0.1 7.1 299.6 6.7 0.0 1.3 34.5 12.2 9.8 43.3 2.7 0.6 16.1 0.0 38.4 5.5 38.8 0.0 0.0 1.6 27.2 39.3 0.4 5.0 13.9 235.1 6.1 33.9 2.7 0.0 5.0 3.3 1.0 1.3 49.3 54.8 52.5 3.3 0.1 20.7 26.6 MFSD4A "DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, UNQ3064" ENSG00000174514 "Major facilitator superfamily domain containing 4A" Q8N468 1 205568885-205602918 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 66.7;stomach 1: 132.6" "Cell type enhanced" "Detected in some" "Adipocytes: 11.3;Collecting duct cells: 9.2;Distal tubular cells: 13.7;Endometrial ciliated cells: 9.9;Glandular and luminal cells: 40.5;Proximal tubular cells: 7.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 17 "amygdala: 11.4;basal ganglia: 8.4;cerebral cortex: 18.4;hippocampal formation: 14.1;white matter: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.8" HPA055407 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA055407: " "unprognostic (7.15e-4)" "prognostic favorable (7.54e-4)" "unprognostic (5.60e-2)" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic favorable (4.59e-4)" "unprognostic (2.73e-2)" "unprognostic (1.65e-2)" "unprognostic (3.20e-2)" "unprognostic (6.97e-3)" "prognostic favorable (2.27e-13)" "unprognostic (1.58e-1)" "unprognostic (4.44e-2)" "unprognostic (5.75e-3)" "unprognostic (8.78e-2)" 2.2 0.4 11.4 1.1 8.4 0.0 2.7 0.6 18.4 8.5 0.0 13.8 1.9 1.0 9.2 1.4 2.5 16.8 0.9 14.1 0.0 66.7 0.2 6.8 0.4 0.0 0.0 0.6 1.4 0.4 1.5 6.2 0.0 1.4 18.2 14.0 17.1 0.6 0.3 5.1 1.4 0.8 0.0 0.6 132.6 0.5 0.0 0.6 0.4 0.7 1.3 0.7 0.8 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 8.4 0.6 18.4 14.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 11.3 6.4 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 3.8 2.9 0.0 0.0 6.2 9.2 0.0 0.5 0.7 0.0 13.7 1.4 0.0 9.9 6.0 2.5 0.0 0.0 0.0 6.2 0.1 0.5 0.0 40.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 7.7 2.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.8 0.2 0.0 0.0 MFSD6 FLJ20160 ENSG00000151690 "Major facilitator superfamily domain containing 6" Q6ZSS7 2 190408355-190509205 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 110.6;Respiratory ciliated cells: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 79.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022274 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA022274: AB_2142776" "unprognostic (9.47e-2)" "unprognostic (7.01e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-2)" "unprognostic (2.49e-1)" "unprognostic (4.13e-3)" "unprognostic (1.78e-2)" "unprognostic (3.08e-2)" "unprognostic (3.92e-1)" "unprognostic (3.77e-1)" "unprognostic (9.54e-2)" "unprognostic (2.08e-1)" "prognostic favorable (1.05e-4)" "unprognostic (3.46e-2)" "unprognostic (3.27e-1)" "unprognostic (9.14e-2)" "unprognostic (9.18e-2)" 20.8 40.3 29.1 12.7 31.7 7.6 21.3 37.0 40.3 21.8 0.0 31.8 19.8 10.5 32.8 40.6 19.5 15.8 17.9 35.5 27.6 10.8 2.3 26.4 14.8 45.8 48.3 4.1 16.8 64.5 35.4 8.6 52.4 23.0 28.9 14.9 30.8 32.3 6.4 29.8 24.6 14.4 28.6 20.9 32.1 7.9 38.3 19.9 38.9 14.2 20.6 22.9 21.5 51.2 25.1 15.2 0.5 5.2 10.6 13.6 20.4 12.7 25.3 8.4 10.5 5.6 31.1 39.1 5.8 26.4 15.6 41.5 7.4 22.1 9.5 79.7 11.6 20.9 14.2 2.9 4.2 8.3 6.4 2.1 39.3 12.5 8.1 27.1 3.0 30.5 5.4 42.2 2.2 9.7 38.8 1.8 3.4 27.1 16.1 8.6 1.2 34.1 15.9 45.1 47.5 12.2 17.9 41.7 24.9 1.7 13.6 9.5 12.6 1.4 2.9 16.6 19.7 19.3 8.6 13.8 13.5 16.9 6.9 4.6 1.1 0.4 1.4 0.3 1.5 1.6 1.8 2.0 1.5 0.7 0.9 1.9 0.1 2.1 0.5 0.7 3.5 0.8 29.1 31.7 37.0 40.3 35.5 27.6 45.8 48.3 52.4 28.6 38.3 51.2 48.6 32.1 20.0 7.2 7.6 6.4 11.5 11.7 10.8 9.7 16.8 9.8 21.4 5.7 30.3 23.9 8.4 0.2 14.9 25.1 0.0 13.2 46.8 27.9 5.9 26.7 35.4 7.8 55.7 20.5 0.2 8.9 31.1 22.5 24.0 8.7 16.1 0.8 4.0 28.6 47.9 42.7 12.2 4.0 8.0 13.7 5.6 12.3 8.8 11.2 9.7 6.8 3.1 41.7 110.6 24.9 20.8 5.3 14.9 13.5 13.6 1.0 88.5 7.9 0.0 16.7 7.2 1.0 1.4 28.8 18.3 0.0 17.0 18.6 21.1 22.7 MGAM2 ENSG00000257743 "Maltase-glucoamylase 2 (putative)" Q2M2H8 7 142111749-142222324 "Enzymes, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 11.8;pancreas: 4.0;salivary gland: 5.9" "Group enriched" "Detected in some" 4 "Early spermatids: 27.4;Late spermatids: 18.2" "Group enriched" "Detected in some" 11 "colorectal cancer: 3.5;pancreatic cancer: 2.5;stomach cancer: 9.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "OE19: 1.6;RH-30: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA055697 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" Vesicles Cytosol "HPA055697: AB_2682890" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-3)" "unprognostic (5.65e-2)" "unprognostic (2.19e-2)" "unprognostic (1.89e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-2)" "unprognostic (5.93e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-1)" "unprognostic (5.50e-4)" "unprognostic (7.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.71e-2)" "unprognostic (9.33e-2)" 0.1 0.0 0.0 0.4 0.0 0.2 1.1 0.0 0.4 0.0 0.2 1.5 11.8 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 5.9 0.0 0.0 0.0 9.6 0.0 0.0 0.9 0.5 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 27.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 MGAT1 "GLCNAC-TI, GLYT1, GNT-1, GnTI, MGAT" ENSG00000131446 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase" P26572 5 180784780-180815652 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 280.2;Syncytiotrophoblasts: 384.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017432 Approved NA NA 12000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA017432: AB_1853851" "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (3.38e-2)" "unprognostic (2.11e-1)" "unprognostic (3.91e-2)" "unprognostic (6.70e-2)" "unprognostic (4.39e-2)" "unprognostic (9.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.98e-1)" "unprognostic (3.70e-3)" "unprognostic (6.44e-2)" "prognostic unfavorable (8.65e-4)" "unprognostic (4.15e-2)" "unprognostic (3.52e-2)" "unprognostic (5.68e-2)" "unprognostic (5.00e-2)" 130.4 66.7 44.0 65.8 43.8 60.6 113.7 40.7 59.9 70.7 64.6 69.8 50.2 75.2 28.2 103.2 85.8 39.9 103.2 38.4 42.0 63.3 146.9 113.3 68.5 56.7 43.2 75.1 115.3 20.3 61.7 67.3 54.0 75.5 30.1 29.2 82.0 37.1 61.1 73.4 82.2 40.9 47.4 139.9 78.1 36.4 64.9 38.3 96.1 35.6 42.2 85.0 72.3 49.3 58.3 58.2 30.9 66.3 149.6 68.7 111.0 130.1 154.4 77.4 96.7 79.4 45.6 50.2 77.3 122.3 78.2 68.8 17.0 190.8 46.1 271.6 47.6 44.2 34.1 61.7 72.8 40.6 137.6 79.7 91.5 63.1 62.9 53.6 67.9 34.2 26.1 84.7 70.9 78.3 38.9 55.2 29.6 37.5 72.0 46.2 44.5 66.8 30.9 67.3 27.2 32.1 54.6 56.5 115.7 27.2 43.8 68.5 72.9 94.7 44.7 42.7 61.1 165.9 149.2 44.7 77.6 78.9 49.8 93.0 228.6 104.6 83.5 186.7 91.6 48.3 60.2 70.3 161.7 42.0 51.4 59.1 152.2 70.4 149.4 152.9 75.3 235.1 44.0 43.8 40.7 59.9 38.4 42.0 56.7 43.2 54.0 47.4 64.9 49.3 157.8 48.1 31.1 9.8 57.7 61.2 44.6 52.8 50.1 20.7 41.5 29.7 18.4 44.3 32.7 29.5 56.3 94.9 114.7 43.8 37.2 49.0 31.7 26.2 34.2 94.2 49.8 47.6 7.5 79.0 280.2 80.5 33.6 48.7 30.4 27.2 125.7 88.1 200.5 63.9 8.5 54.9 20.3 195.5 142.1 43.2 62.7 234.9 81.8 26.2 112.1 18.9 87.6 8.0 14.6 54.0 34.7 76.0 169.7 76.9 57.2 22.5 20.4 78.8 32.9 72.1 51.5 26.8 22.5 46.8 63.9 384.9 59.3 43.7 36.7 56.8 MGME1 "bA504H3.4, C20orf72, DDK1" ENSG00000125871 "Mitochondrial genome maintenance exonuclease 1" Q9BQP7 20 17969018-17991122 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040913 Approved Supported Mitochondria NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA040913: AB_10962835" "unprognostic (5.81e-3)" "unprognostic (5.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.29e-3)" "unprognostic (5.42e-2)" "unprognostic (1.44e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (5.31e-2)" "unprognostic (7.05e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (8.70e-2)" "unprognostic (6.89e-2)" 6.5 14.4 7.5 11.7 8.2 16.0 18.4 8.0 9.7 7.3 7.9 11.4 13.4 5.2 10.4 13.1 6.2 7.3 10.8 7.2 7.5 12.8 14.4 7.7 19.9 8.6 8.1 5.9 8.8 7.8 4.7 12.8 8.7 7.5 13.4 7.8 9.0 7.4 21.3 34.2 11.9 6.7 8.3 17.7 9.3 10.7 7.9 19.8 11.9 12.1 20.8 8.9 9.5 9.3 44.7 51.0 41.0 38.7 16.5 29.0 54.9 36.8 27.1 34.8 47.4 63.4 44.7 53.4 20.3 16.4 39.6 64.9 43.1 55.1 52.7 19.9 34.7 34.7 29.6 97.2 12.3 22.9 56.2 17.6 37.3 52.3 27.4 16.3 28.2 26.0 48.0 33.3 70.7 33.4 40.5 29.9 36.3 26.8 44.0 30.5 91.4 50.8 30.1 32.3 31.6 26.1 26.1 62.8 57.7 33.2 59.7 15.5 22.8 59.1 48.1 29.8 40.3 24.6 59.6 45.3 15.2 17.3 44.7 57.5 15.2 44.6 8.1 14.9 10.9 21.0 10.5 10.9 12.6 24.2 7.5 6.9 14.4 16.7 15.0 19.5 17.1 8.4 7.5 8.2 8.0 9.7 7.2 7.5 8.6 8.1 8.7 8.3 7.9 9.3 10.6 0.0 10.0 19.9 24.6 46.4 15.7 12.7 40.9 7.9 19.9 39.4 12.6 15.7 11.9 7.3 8.4 22.9 21.0 14.3 39.2 13.1 9.8 11.2 15.6 11.9 7.2 52.6 3.1 10.2 25.9 8.1 5.1 13.3 48.0 25.5 20.0 9.9 31.4 8.4 2.9 12.1 6.1 34.4 15.4 5.5 8.4 18.8 21.4 9.4 16.4 11.4 28.8 17.6 12.6 10.4 10.6 5.7 13.2 12.3 31.0 26.5 5.9 10.0 13.1 10.3 10.8 38.6 47.0 20.5 46.9 18.1 14.9 27.1 19.0 12.8 MGST1 "GST12, MGST-I" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1096.9;adrenal gland: 1137.3;liver: 3104.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1205.9;Club cells: 1308.7;Hepatocytes: 4345.6;Proximal tubular cells: 1265.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 170.2;myeloid DC: 123.5" "Group enriched" "Detected in many" 13 "dendritic cells: 123.5;monocytes: 170.2" "Cell line enhanced" "Detected in many" "ASC diff: 5391.4;ASC TERT1: 2078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 19000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Endoplasmic reticulum" "HPA044840: AB_10965550" "unprognostic (4.57e-2)" "unprognostic (4.80e-3)" "unprognostic (5.82e-2)" "unprognostic (2.92e-3)" "unprognostic (3.97e-3)" "unprognostic (1.03e-1)" "unprognostic (8.19e-2)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (3.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (9.90e-2)" "unprognostic (4.61e-1)" "prognostic favorable (1.97e-4)" "unprognostic (4.19e-1)" 1096.9 1137.3 139.2 76.1 143.9 79.3 574.8 131.4 200.7 69.7 111.9 315.5 128.9 32.7 43.9 195.3 78.4 200.8 135.1 133.9 165.4 392.9 3104.7 177.2 3.5 156.5 155.7 11.4 131.3 0.8 52.6 14.2 166.6 161.2 212.8 7.0 155.3 55.8 25.5 88.8 119.5 44.7 146.4 7.3 131.4 20.2 147.5 14.0 272.3 43.3 7.7 267.9 114.7 132.9 1.4 495.2 115.6 139.4 5391.4 2078.4 1.5 408.5 418.5 220.6 339.1 186.0 838.6 0.4 48.5 535.8 694.2 2.4 317.0 663.5 202.9 1.1 41.4 175.7 256.6 664.8 1252.0 350.4 1.2 1375.9 714.7 671.2 710.5 540.4 393.1 0.1 126.7 0.6 486.3 101.2 0.3 137.0 987.6 0.7 391.2 0.4 69.3 229.3 503.3 982.1 21.8 17.1 645.8 411.8 17.5 630.1 442.5 190.8 248.0 226.1 30.5 447.3 541.1 0.6 1.7 1.5 748.1 538.5 7.1 11.3 170.2 1.8 0.1 26.3 0.5 1.0 0.2 0.1 123.5 0.0 0.1 0.1 5.9 0.2 5.9 34.1 1.1 55.9 139.2 143.9 131.4 200.7 133.9 165.4 156.5 155.7 166.6 146.4 147.5 132.9 39.6 266.0 651.3 130.2 14.0 25.6 130.2 1205.9 91.0 0.0 383.8 262.6 5.1 574.7 1308.7 71.7 0.0 2.9 9.8 288.1 181.9 26.9 25.4 299.9 198.2 19.6 45.6 92.8 4.4 434.1 218.1 404.5 153.9 947.9 34.1 26.3 67.5 4345.6 160.2 0.0 0.5 280.5 740.6 176.4 52.0 17.9 33.2 75.7 39.2 6.5 224.4 1.0 5.2 1.0 0.8 322.7 175.0 113.2 6.0 467.2 209.5 1265.6 526.1 1.3 0.0 11.3 124.3 0.7 2.3 510.3 17.6 7.9 22.1 152.4 534.1 883.3 MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 441.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 194.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 276.3;OE19: 558.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010690, HPA010707" Enhanced Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Endoplasmic reticulum" "HPA010690: , HPA010707: AB_1853922" "unprognostic (9.35e-2)" "unprognostic (6.13e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (4.38e-2)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (6.41e-2)" "prognostic favorable (3.22e-9)" "unprognostic (4.10e-1)" "unprognostic (9.91e-2)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" 61.8 92.7 43.5 30.4 42.9 42.6 66.6 45.1 60.6 63.6 54.8 112.5 132.5 39.2 82.1 177.6 70.8 87.6 118.3 42.6 45.7 99.2 393.2 49.0 36.0 46.6 44.6 26.3 66.2 102.0 44.6 75.6 46.5 74.9 121.2 7.8 90.6 50.0 104.2 97.1 143.5 57.4 46.6 60.5 72.5 50.6 45.3 35.1 45.8 118.4 64.6 86.7 78.4 48.9 40.8 58.5 28.7 0.3 4.8 15.4 17.7 7.2 66.1 3.2 10.7 62.3 276.3 0.1 158.2 17.5 13.6 74.8 52.7 81.2 4.9 22.3 47.7 174.9 57.3 251.5 13.3 152.7 130.0 53.0 197.2 2.1 12.5 63.9 166.3 0.3 75.9 25.7 23.3 33.9 0.2 24.7 6.5 558.9 59.4 12.7 33.4 54.0 153.0 87.4 71.9 21.6 53.2 83.2 64.8 2.0 52.9 202.2 104.9 5.6 27.3 7.8 6.4 29.7 22.5 9.7 3.8 254.8 12.6 43.8 103.8 30.4 4.1 64.8 2.9 1.3 7.6 3.5 147.0 2.4 2.3 2.6 17.7 26.4 22.2 194.6 37.7 39.4 43.5 42.9 45.1 60.6 42.6 45.7 46.6 44.6 46.5 46.6 45.3 48.9 327.9 25.6 36.6 5.5 7.7 61.1 295.9 316.7 75.7 7.8 99.1 57.3 100.5 205.9 185.5 95.6 25.0 85.3 71.0 168.3 90.1 121.0 6.3 132.5 27.1 238.4 121.8 60.2 19.4 138.6 62.8 31.8 90.2 172.9 43.2 56.9 203.1 419.3 378.1 6.7 24.2 215.1 170.9 107.8 77.8 12.8 44.4 85.3 39.2 49.6 83.6 14.1 27.8 11.6 4.7 121.8 213.1 33.4 7.1 94.6 441.1 277.2 126.6 3.5 13.1 44.6 49.6 4.6 15.1 264.0 124.9 67.2 15.2 43.6 258.2 344.9 MIA CD-RAP ENSG00000261857 "MIA SH3 domain containing" Q16674 19 40771648-40777490 "Cancer-related genes, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 57.9;pituitary gland: 76.2;salivary gland: 43.3;stomach 1: 65.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 51.4;Breast myoepithelial cells: 171.7;Melanocytes: 103.2;monocytes: 30.0;Pancreatic endocrine cells: 66.8;Respiratory ciliated cells: 53.9" "Cancer enriched" "Detected in many" 5 "melanoma: 58.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Group enriched" "Detected in some" 29 "AN3-CA: 90.1;CAPAN-2: 80.6;SK-MEL-30: 271.9;WM-115: 247.7" HPA042369 Approved "Secreted to blood" NA NA 8270000 64000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 4: Stomach - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA042369: AB_10794420" "prognostic favorable (2.08e-4)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "unprognostic (9.02e-3)" "unprognostic (2.27e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-3)" "unprognostic (3.67e-2)" "unprognostic (1.61e-1)" "unprognostic (9.37e-2)" "unprognostic (1.17e-1)" "unprognostic (3.19e-1)" "unprognostic (3.29e-8)" "unprognostic (5.88e-2)" "unprognostic (2.44e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" 2.6 2.9 4.9 6.9 5.9 2.9 57.9 5.7 7.5 8.3 5.4 16.9 2.0 1.2 2.0 6.6 3.7 2.9 5.3 4.4 4.8 2.4 2.7 1.9 2.0 5.3 5.0 7.0 1.4 0.0 76.2 2.1 5.6 6.4 4.2 0.4 43.3 3.3 0.7 9.6 5.9 7.6 4.8 7.0 65.8 1.7 5.5 2.4 2.9 1.7 1.6 4.0 5.2 7.9 0.3 0.9 1.5 90.1 1.3 1.2 1.0 0.0 0.0 0.0 0.5 0.5 80.6 0.2 0.0 0.0 0.3 0.2 0.4 4.9 0.1 2.9 0.9 0.0 1.0 0.1 0.4 0.2 0.4 0.7 4.2 0.0 1.5 1.4 0.0 1.4 0.0 0.9 0.0 0.0 0.1 0.0 0.2 5.9 0.3 0.1 0.2 0.0 2.5 0.0 0.2 0.1 0.1 0.0 271.9 3.4 0.5 1.2 0.0 0.2 3.4 0.1 1.0 0.0 0.2 0.9 0.1 0.4 247.7 0.6 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 4.9 5.9 5.7 7.5 4.4 4.8 5.3 5.0 5.6 4.8 5.5 7.9 1.0 0.0 0.5 0.0 0.3 5.2 0.1 11.2 0.6 0.0 51.4 171.7 0.6 0.0 4.9 0.0 0.0 0.8 0.5 1.7 0.0 0.5 0.0 0.9 0.0 1.4 0.0 0.0 0.0 3.2 0.1 1.1 14.3 0.2 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.1 4.1 0.0 0.7 0.3 0.6 0.2 103.2 0.0 30.0 0.0 0.0 0.0 0.0 66.8 5.1 0.0 0.1 0.8 0.4 0.0 53.9 0.0 0.0 0.2 1.3 0.1 0.6 6.1 1.3 0.7 0.3 0.8 4.1 0.5 MID1IP1 "FLJ10386, G12-like, MIG12, STRAIT11499, THRSPL" ENSG00000165175 "MID1 interacting protein 1" Q9NPA3 X 38801432-38806537 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 150.2" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 217.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 15.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038816 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA038816: AB_10670908" "unprognostic (5.35e-2)" "unprognostic (1.75e-1)" "unprognostic (1.24e-1)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.62e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-2)" "unprognostic (2.88e-1)" "unprognostic (2.31e-3)" "prognostic favorable (1.15e-4)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (1.18e-2)" "prognostic favorable (8.06e-4)" 40.2 34.1 102.1 13.9 143.4 103.6 34.5 106.6 105.3 20.4 50.4 45.0 17.0 18.3 6.9 35.5 30.9 7.5 39.5 78.6 91.9 29.5 56.1 43.7 11.1 115.4 123.4 33.4 78.7 4.0 15.4 8.7 107.4 23.0 5.0 3.4 25.0 13.3 150.2 28.7 25.1 9.3 99.2 12.3 49.7 23.0 127.8 9.1 13.8 25.9 6.2 35.5 24.3 139.5 60.3 55.2 14.3 10.9 67.9 31.8 15.4 33.2 23.2 7.1 13.5 18.5 44.3 57.7 28.4 10.7 6.0 55.3 47.7 39.4 4.7 39.9 18.7 49.4 48.7 14.9 51.6 23.1 36.7 46.4 31.1 27.7 24.2 19.1 7.2 68.9 46.5 60.7 10.1 50.4 40.8 64.3 49.5 17.6 95.9 111.2 17.6 116.4 18.5 29.8 34.0 41.3 17.6 34.0 90.9 28.2 28.0 70.5 10.0 20.2 22.4 25.5 24.6 155.5 65.0 53.6 61.1 37.4 22.3 3.8 1.9 15.7 0.9 1.3 1.0 0.5 1.4 1.0 1.3 0.7 1.2 1.2 8.0 0.8 2.0 1.3 0.5 0.9 102.1 143.4 106.6 105.3 78.6 91.9 115.4 123.4 107.4 99.2 127.8 139.5 20.3 80.1 217.9 11.4 17.4 23.7 48.5 63.0 44.3 12.5 22.4 21.1 40.5 52.9 28.2 20.2 4.2 3.7 16.6 23.3 37.2 36.7 8.3 65.6 25.0 25.3 25.8 54.1 1.7 70.0 20.2 57.7 49.5 20.8 48.8 13.2 24.3 40.5 40.4 15.2 2.7 33.2 63.1 53.2 73.8 12.7 39.4 60.5 26.6 5.6 130.4 20.7 8.2 3.5 47.6 67.0 24.4 49.7 6.9 36.7 18.1 47.9 48.0 12.4 39.5 42.7 52.8 2.4 3.7 63.0 16.3 4.9 35.4 16.3 25.5 116.9 MID2 "FXY2, MRX101, RNF60, TRIM1" ENSG00000080561 "Midline 2" Q9UJV3 X 107825755-107931637 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.5;Inhibitory neurons: 21.5;Urothelial cells: 11.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 6 "T-cells: 1.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 41.5;Karpas-707: 35.5;MCF7: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (8.28e-2)" "unprognostic (8.51e-2)" "unprognostic (3.69e-4)" "unprognostic (6.40e-3)" "unprognostic (1.16e-1)" "unprognostic (7.50e-2)" "unprognostic (3.87e-1)" "unprognostic (7.20e-2)" "unprognostic (1.09e-2)" "unprognostic (4.87e-2)" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (3.19e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (3.77e-1)" "unprognostic (5.97e-3)" 11.2 9.2 5.2 3.9 6.1 0.4 7.2 4.4 4.2 8.3 4.2 6.0 1.8 9.4 8.0 13.6 8.8 7.7 3.1 3.5 12.1 6.0 5.4 6.4 4.4 7.4 7.1 9.3 9.6 12.9 3.2 4.4 9.1 10.3 3.6 14.8 11.1 9.6 12.9 9.6 2.6 15.8 6.3 3.8 4.4 2.1 9.0 2.3 13.2 18.5 5.2 10.6 7.5 4.8 8.4 7.1 0.2 11.2 8.8 12.3 0.1 5.9 15.0 5.0 3.6 0.6 1.5 0.0 7.5 11.7 8.3 5.2 4.1 12.1 1.1 0.0 5.5 0.0 4.2 0.0 13.5 0.0 0.0 8.0 13.3 0.1 14.5 9.1 41.5 0.5 0.0 35.5 5.6 26.8 0.1 0.0 1.2 0.3 13.0 0.0 3.2 0.0 6.3 7.5 0.6 0.0 12.6 0.5 18.6 3.9 4.6 0.5 8.2 0.0 2.1 9.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.8 1.4 0.0 0.2 1.6 1.1 0.0 0.0 0.0 0.0 0.1 0.4 5.2 6.1 4.4 4.2 3.5 12.1 7.4 7.1 9.1 6.3 9.0 4.8 3.1 3.2 0.0 8.1 0.4 3.1 3.3 0.9 4.0 1.9 2.3 1.8 0.6 1.5 1.1 0.0 0.0 0.0 0.3 0.3 1.9 1.8 1.1 1.0 1.7 2.6 0.0 0.0 14.5 1.5 0.0 1.5 1.1 1.5 0.0 0.3 2.2 1.8 0.1 0.0 21.5 0.2 0.0 0.0 0.0 1.4 0.0 0.2 3.6 7.5 0.0 0.8 0.0 8.0 7.4 1.1 0.0 0.7 1.1 4.2 0.5 0.8 2.3 3.9 0.0 1.9 2.1 0.2 0.4 3.9 3.7 0.0 1.7 0.8 0.4 11.4 MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 108.0;Oligodendrocytes: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 64.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA030676: AB_10598907, HPA031669: AB_10600986, HPA031670: AB_10602198" "unprognostic (2.05e-1)" "unprognostic (3.17e-2)" "unprognostic (3.75e-3)" "unprognostic (3.72e-2)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.12e-1)" "unprognostic (7.54e-2)" "unprognostic (4.76e-1)" "prognostic favorable (7.66e-12)" "unprognostic (1.62e-2)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (6.90e-3)" 6.3 9.6 3.7 6.2 4.3 5.3 11.1 3.2 5.0 7.5 13.4 12.9 8.8 7.2 12.4 11.5 17.3 7.7 18.4 14.4 4.0 25.4 12.0 7.1 5.1 4.0 5.0 5.4 8.2 14.6 5.4 4.7 4.6 10.9 13.1 6.1 9.7 8.7 13.9 21.4 7.6 7.8 4.0 4.3 8.6 9.8 3.7 6.0 11.1 16.9 7.8 7.7 6.4 4.9 14.6 16.1 7.8 18.4 17.4 23.4 16.6 10.3 16.0 15.1 12.7 21.7 28.1 17.0 10.2 8.4 13.3 35.8 18.1 21.6 18.8 9.9 11.5 7.4 7.0 18.8 14.3 17.5 3.9 11.6 26.4 15.7 13.9 12.7 19.2 12.7 14.5 2.7 24.0 10.8 12.6 9.8 10.8 64.8 16.1 13.8 21.0 14.8 33.7 9.6 18.2 6.1 11.0 17.8 21.8 9.8 18.3 9.7 10.7 9.2 7.6 15.3 11.2 2.6 4.0 9.1 15.9 8.8 11.7 0.0 3.0 1.3 7.4 3.7 9.3 8.7 7.1 6.8 6.5 7.2 6.7 6.7 0.0 10.3 12.0 5.5 5.2 4.0 3.7 4.3 3.2 5.0 14.4 4.0 4.0 5.0 4.6 4.0 3.7 4.9 2.5 16.0 8.6 18.9 5.9 39.9 7.7 13.8 6.2 3.6 6.2 5.8 108.0 11.5 12.6 9.2 6.2 9.8 2.4 8.2 29.4 23.4 8.2 26.0 8.5 5.4 6.0 4.6 43.8 10.6 9.3 8.0 7.1 8.5 2.5 4.2 3.6 5.9 9.7 15.2 47.5 7.1 14.2 3.5 5.0 7.4 6.8 4.3 5.4 12.2 3.4 5.5 5.2 18.1 62.8 8.6 7.0 8.6 4.9 7.5 6.6 25.6 46.3 11.4 0.0 7.3 5.7 9.7 19.0 10.1 42.3 5.1 4.0 8.9 13.6 5.6 MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 196.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 793.4;Intestinal goblet cells: 230.9;Paneth cells: 646.7;Proximal enterocytes: 1115.2;Undifferentiated cells: 220.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 121.4;HaCaT: 90.2;hTCEpi: 82.6;MCF7: 63.2;OE19: 76.9;SK-BR-3: 134.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" 1.3 0.0 0.3 12.1 0.3 0.0 0.9 0.5 0.4 4.4 0.1 95.5 171.0 0.7 0.0 0.3 9.8 11.3 0.0 0.4 0.3 8.8 0.1 9.3 0.1 0.5 0.5 0.3 1.7 0.0 8.1 1.2 0.5 5.6 48.4 0.0 1.0 0.5 0.0 0.6 196.6 3.3 0.2 0.0 22.9 0.5 0.3 0.3 0.1 0.0 0.0 9.0 0.6 0.2 30.4 121.4 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 42.1 44.2 10.8 11.5 0.0 0.1 90.2 0.0 37.7 0.0 0.0 0.1 0.0 47.0 13.3 0.0 0.0 1.9 0.0 82.6 0.3 4.5 0.0 0.0 0.0 0.0 0.4 0.2 63.2 0.1 0.7 0.1 76.9 24.6 0.2 0.4 1.0 30.1 33.7 1.4 0.4 42.9 134.3 0.1 0.1 29.3 0.0 0.0 0.0 14.8 1.8 0.2 0.6 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.4 0.4 0.3 0.5 0.5 0.5 0.2 0.3 0.2 0.1 38.5 8.0 0.3 2.9 0.1 4.5 22.5 0.0 0.0 4.7 2.3 0.5 10.0 39.7 11.0 0.0 0.6 0.0 793.4 1.9 39.9 0.6 40.5 1.5 0.8 58.0 0.0 0.2 46.0 6.0 2.4 56.6 14.3 8.9 0.0 0.0 0.0 0.1 0.0 0.3 230.9 28.5 0.0 0.0 0.9 0.0 0.6 0.0 1.0 0.6 0.0 0.0 0.0 0.2 157.7 646.7 0.0 0.1 41.6 1115.2 27.5 41.3 0.0 0.0 0.0 2.6 0.0 1.2 0.0 0.3 2.1 1.6 0.0 220.7 62.1 MISP3 ENSG00000141854 "MISP family member 3" Q96FF7 19 14072536-14075062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 17.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 19.3;Breast myoepithelial cells: 20.8;Collecting duct cells: 14.7;Distal tubular cells: 35.2;Endometrial ciliated cells: 12.4;Exocrine glandular cells: 11.5;Proximal tubular cells: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 5.3;OE19: 11.3;RPMI-8226: 6.3;U-266/84: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042225 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" "HPA042225: AB_10795396" "unprognostic (1.69e-1)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (7.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.01e-2)" "unprognostic (3.66e-2)" "unprognostic (1.76e-3)" "unprognostic (9.77e-2)" "unprognostic (1.31e-2)" "unprognostic (8.81e-2)" "unprognostic (1.46e-1)" "prognostic favorable (9.52e-4)" "prognostic favorable (3.11e-5)" "unprognostic (2.97e-1)" "unprognostic (1.01e-1)" "unprognostic (9.78e-2)" 1.4 2.1 7.2 0.3 7.3 0.5 2.0 7.6 10.3 2.0 6.3 7.6 3.9 1.0 0.4 3.0 3.0 0.3 6.3 7.6 8.1 17.7 5.6 2.9 0.0 7.4 7.4 0.5 12.1 2.8 2.6 0.5 7.6 3.6 1.4 1.1 7.8 1.0 2.5 7.9 5.2 0.1 7.7 1.3 11.1 0.9 7.5 0.2 3.0 1.0 0.1 1.7 2.8 7.8 1.7 0.9 0.3 0.7 0.6 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.3 0.1 1.1 0.1 0.0 0.6 0.8 0.0 0.0 2.1 1.5 0.2 0.3 0.8 0.1 0.1 0.3 0.1 0.0 0.0 0.1 0.7 0.2 1.0 0.2 5.3 0.0 3.0 0.3 0.7 0.0 11.3 0.7 0.5 0.1 6.3 1.1 0.0 1.5 0.4 0.0 0.5 0.6 0.0 0.9 0.0 0.1 0.0 0.4 0.5 0.0 3.6 4.3 0.4 0.8 1.3 0.1 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 7.2 7.3 7.6 10.3 7.6 8.1 7.4 7.4 7.6 7.7 7.5 7.8 3.2 9.6 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 19.3 20.8 0.0 0.0 1.8 14.7 0.0 0.2 3.7 0.0 35.2 2.5 0.0 12.4 0.8 0.7 0.0 0.0 0.0 11.5 0.1 1.0 0.0 5.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 1.3 0.0 0.0 22.8 2.9 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 3.0 1.5 0.3 0.0 0.0 MKI67 "MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 46.3;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 232.9;Extravillous trophoblasts: 86.1;Granulosa cells: 87.0;Plasma cells: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB000058, HPA000451, HPA001164, CAB068198" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "CAB000058: AB_2142367, CAB068198: AB_2665702, HPA000451: AB_1079186, HPA001164: AB_1079187" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (9.92e-3)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.61e-6)" "unprognostic (7.16e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (9.47e-5)" "unprognostic (2.45e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (4.61e-1)" 0.9 0.7 0.0 8.5 0.1 46.3 1.7 0.0 0.1 1.2 0.2 8.1 6.2 1.0 0.0 10.0 0.3 0.9 0.3 0.1 0.1 0.4 0.8 1.4 14.9 0.1 1.0 0.2 0.2 0.1 0.1 4.1 0.6 0.4 9.2 0.0 1.4 0.1 0.0 6.6 5.8 2.6 0.0 4.8 4.2 2.3 0.9 52.7 0.4 0.1 16.4 1.8 2.8 0.3 204.6 101.5 103.2 73.6 4.3 8.7 32.1 75.7 55.3 70.3 62.3 83.9 82.3 152.6 21.3 51.9 46.4 120.7 109.3 56.8 104.7 161.8 53.1 131.0 79.4 52.7 0.1 186.0 68.0 2.0 2.5 72.2 73.2 17.2 69.8 69.5 61.2 142.1 70.5 80.9 111.7 56.6 41.3 52.7 45.7 82.2 135.1 20.3 25.6 56.2 35.9 38.9 107.1 38.0 17.3 33.9 31.4 39.3 65.0 37.0 73.6 53.0 206.8 64.2 54.9 177.2 30.7 83.3 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.6 0.0 0.9 0.3 0.6 0.0 5.4 0.0 16.0 6.4 1.6 5.3 0.6 0.0 3.9 3.2 1.6 1.5 5.3 0.0 0.0 30.6 7.4 25.0 0.0 0.8 4.2 2.3 10.2 6.7 6.7 232.9 0.0 0.0 86.1 13.5 34.7 13.2 1.3 87.0 5.7 1.7 42.1 0.0 0.0 22.4 2.0 12.9 13.7 0.9 0.3 16.6 3.6 0.0 0.2 0.0 8.2 0.0 0.0 0.1 3.0 0.4 107.4 4.6 2.6 0.1 1.6 0.0 0.0 0.5 13.6 8.1 24.1 50.4 3.0 7.8 23.0 2.7 47.1 4.8 MLANA MART1 ENSG00000120215 Melan-A Q16655 9 5890889-5910606 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 42.9" "Cell type enriched" "Detected in some" 23 "Melanocytes: 1718.2" "Cancer enriched" "Detected in single" 556 "melanoma: 277.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 406 "SK-MEL-30: 703.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000057, HPA048662" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "CAB000057: AB_442107, HPA048662: AB_2680485" "unprognostic (2.52e-2)" "unprognostic (6.87e-2)" "unprognostic (5.20e-2)" "unprognostic (5.61e-2)" "unprognostic (2.58e-2)" "unprognostic (1.46e-1)" "unprognostic (4.53e-1)" "unprognostic (3.32e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-3)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (1.45e-2)" "unprognostic (1.60e-1)" "unprognostic (8.01e-2)" "unprognostic (5.78e-2)" "unprognostic (9.43e-2)" 0.1 0.2 0.3 0.4 0.5 0.7 1.4 2.0 0.6 0.1 5.9 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.3 0.4 0.1 0.4 0.5 0.3 0.1 0.1 0.0 0.1 0.1 0.5 0.1 0.0 0.3 1.1 0.0 0.3 42.9 0.1 0.0 0.1 0.2 0.2 0.3 0.6 0.1 0.2 0.0 0.0 0.2 0.3 0.8 0.8 0.6 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.2 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.2 1.7 1.3 1.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.9 0.0 0.3 0.1 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.1 0.4 0.1 703.0 0.1 0.1 0.3 0.6 0.2 0.4 0.1 0.7 0.2 0.7 0.3 0.2 0.4 0.1 0.8 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.1 0.0 0.3 0.1 0.2 0.4 0.2 0.1 0.2 0.1 0.0 0.3 0.5 2.0 0.6 0.2 0.1 0.5 0.3 0.5 0.1 0.6 0.8 0.0 0.0 0.0 0.3 0.0 73.7 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.2 0.9 0.0 0.0 1.3 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 15.5 0.9 0.0 0.2 1718.2 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.3 14.5 0.0 0.5 0.1 0.0 0.0 MLLT11 AF1Q ENSG00000213190 "MLLT11 transcription factor 7 cofactor" Q13015 1 151060397-151069544 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 54.1;Early spermatids: 76.9;Excitatory neurons: 57.9;Late spermatids: 215.6" "Cancer enriched" "Detected in all" 4 "glioma: 29.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 216.7;EFO-21: 164.9;SH-SY5Y: 238.6;U-698: 207.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000540 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA000540: AB_2666024" "unprognostic (2.96e-2)" "unprognostic (1.98e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.26e-5)" "unprognostic (1.69e-1)" "unprognostic (1.96e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.49e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (4.25e-12)" "unprognostic (5.66e-3)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (3.94e-3)" 5.3 19.0 59.4 4.7 61.8 2.0 2.5 41.1 109.3 4.5 8.8 7.2 1.6 10.7 1.3 4.0 6.2 6.0 38.1 66.2 80.6 3.8 2.0 3.8 2.1 63.1 50.5 8.2 3.1 16.2 10.4 1.0 66.1 4.3 3.6 35.6 3.8 1.5 11.3 2.6 4.9 13.8 29.9 4.6 5.1 2.8 49.7 20.6 3.8 10.8 2.1 4.0 3.9 57.1 6.3 31.0 216.7 34.4 3.5 5.8 1.4 11.6 15.2 13.2 24.0 3.0 12.6 10.0 164.9 10.6 35.9 4.5 54.3 13.0 7.6 65.8 14.5 28.9 17.7 0.9 6.9 0.8 1.0 9.9 1.6 73.5 2.9 42.2 100.1 43.3 30.8 2.3 43.6 1.4 106.4 19.0 95.7 0.6 4.4 99.8 28.1 0.6 25.5 1.7 132.8 238.6 0.8 1.3 6.9 142.5 5.3 2.7 65.9 27.0 29.0 9.2 24.7 2.4 3.2 207.1 70.0 0.6 51.7 1.1 0.3 1.4 5.9 0.6 2.7 2.5 3.9 6.2 0.7 1.9 5.3 9.1 1.6 4.0 0.9 1.4 4.1 3.2 59.4 61.8 41.1 109.3 66.2 80.6 63.1 50.5 66.1 29.9 49.7 57.1 1.4 0.0 1.1 11.8 4.2 3.6 5.0 14.6 4.6 54.1 2.5 4.8 10.2 1.5 2.2 3.7 8.4 2.9 15.3 0.1 17.6 3.9 76.9 0.8 11.3 5.2 10.7 6.3 57.9 1.2 2.5 17.5 2.0 0.9 4.5 4.3 4.2 0.4 6.0 37.0 40.6 0.1 16.2 6.6 14.5 215.6 2.1 12.3 5.4 10.3 33.3 20.6 19.6 16.1 14.4 3.0 0.2 3.8 4.8 1.3 0.2 2.4 0.6 26.3 0.0 3.4 30.0 8.6 12.3 2.8 3.4 7.4 9.9 3.0 0.2 4.3 MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 609.7" "Group enriched" "Detected in many" 4 "Cholangiocytes: 84.4;Enteroendocrine cells: 90.1;Hepatocytes: 286.6;Proximal enterocytes: 108.9" "Cancer enriched" "Detected in many" 6 "liver cancer: 60.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 46.5;K-562: 15.2;SCLC-21H: 25.5;T-47d: 11.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "HPA064640: AB_2685309" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.06e-3)" "unprognostic (3.46e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (6.13e-3)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (2.46e-2)" "unprognostic (7.72e-3)" 72.3 85.1 5.5 0.7 4.1 0.2 51.2 16.3 9.4 3.0 0.2 7.8 58.8 0.6 16.3 3.4 12.9 5.5 3.5 4.5 1.4 36.2 609.7 2.7 0.0 5.6 1.4 4.9 23.1 6.3 13.4 0.0 6.1 3.7 1.5 0.7 8.7 0.8 58.1 4.5 46.8 0.5 1.3 0.3 4.7 30.9 2.2 0.9 7.3 13.8 0.0 2.0 2.7 2.1 0.2 2.5 0.0 5.9 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.3 7.5 0.0 0.3 0.0 0.6 1.2 0.0 0.0 0.0 0.2 6.1 0.0 4.8 46.5 1.3 0.2 1.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.1 6.3 0.1 0.0 0.7 8.2 1.0 0.0 0.0 1.2 0.0 0.1 25.5 0.7 1.0 4.4 0.0 0.1 11.4 6.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 4.1 16.3 9.4 4.5 1.4 5.6 1.4 6.1 1.3 2.2 2.1 0.6 0.0 16.2 2.3 1.6 1.1 4.8 0.6 0.6 9.9 1.4 1.3 3.4 84.4 4.7 3.7 20.9 0.1 0.3 3.2 1.9 2.9 3.2 0.7 0.2 2.5 90.1 16.0 33.4 1.0 0.1 6.5 4.6 0.8 0.0 0.1 12.8 286.6 0.4 1.7 29.1 19.6 0.0 11.2 1.5 1.2 2.8 2.8 7.2 30.9 0.2 2.0 1.0 2.0 0.9 1.4 13.9 1.2 0.1 2.2 108.9 14.1 3.2 6.5 0.0 23.9 1.0 5.1 1.1 0.5 0.9 0.5 1.7 0.0 31.9 4.0 MMAA cblA ENSG00000151611 "Metabolism of cobalamin associated A" Q8IVH4 4 145599042-145660033 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 24.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037361, HPA058187" Supported Supported Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA037361: AB_10672107, HPA058187: " "unprognostic (1.20e-1)" "unprognostic (5.07e-2)" "prognostic favorable (3.38e-4)" "unprognostic (1.97e-3)" "unprognostic (1.44e-1)" "unprognostic (4.83e-3)" "unprognostic (1.31e-3)" "unprognostic (3.98e-1)" "unprognostic (7.03e-2)" "unprognostic (7.26e-2)" "unprognostic (3.19e-3)" "unprognostic (1.46e-1)" "prognostic favorable (2.23e-5)" "unprognostic (3.40e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "prognostic favorable (3.21e-4)" 4.1 3.2 1.4 3.0 1.9 1.7 4.2 2.7 2.3 3.0 1.3 5.8 7.4 2.4 4.0 4.1 2.7 3.8 3.3 1.5 1.4 7.3 24.5 3.7 3.1 1.3 1.5 2.3 2.0 4.2 0.7 2.8 1.3 2.3 5.3 1.9 3.5 2.8 4.7 3.8 6.2 2.6 1.2 3.5 3.6 4.5 1.3 5.2 3.1 6.0 3.7 4.7 0.8 1.6 2.5 1.4 4.0 2.1 8.4 9.8 1.1 7.1 4.0 2.3 1.4 1.7 4.3 12.1 2.1 4.4 1.1 2.2 2.0 4.4 1.7 7.5 0.8 4.0 1.3 1.5 6.5 5.6 3.3 5.5 6.1 2.6 5.8 3.7 7.2 8.1 1.1 4.6 5.1 3.4 7.2 1.4 1.5 6.2 2.7 3.7 2.2 1.4 13.3 1.3 1.9 1.4 3.5 6.0 3.3 2.4 3.9 1.5 7.0 2.8 1.4 5.0 1.6 2.2 2.0 3.3 4.4 5.5 2.8 3.9 3.1 3.0 4.5 6.1 4.0 3.1 5.3 4.6 3.2 2.6 4.0 5.3 0.5 4.8 7.4 3.3 5.2 2.3 1.4 1.9 2.7 2.3 1.5 1.4 1.3 1.5 1.3 1.2 1.3 1.6 3.6 12.8 5.6 5.5 3.6 2.9 10.4 7.7 5.7 3.4 3.0 2.4 7.6 14.3 13.0 11.0 2.1 7.9 6.5 7.7 15.6 11.1 10.5 5.0 4.5 4.1 2.4 1.7 5.7 12.5 2.8 4.8 7.1 5.7 8.2 3.4 7.9 31.8 4.9 0.0 5.7 6.5 8.2 4.1 1.6 6.3 4.7 3.6 1.8 3.7 5.6 2.3 9.2 8.0 7.4 8.4 7.3 3.0 2.8 6.5 10.9 21.1 6.8 1.6 0.0 4.2 3.8 8.7 5.2 4.4 1.1 7.7 4.5 5.7 6.7 12.2 MMAB "cblB, CFAP23" ENSG00000139428 "Metabolism of cobalamin associated B" Q96EY8 12 109553715-109573580 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 103.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 225.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039017 Supported Approved Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 15: Hepatocytes - Hemostasis" Mitochondria "HPA039017: AB_10673603" "unprognostic (1.16e-1)" "unprognostic (1.25e-2)" "unprognostic (1.90e-1)" "unprognostic (1.79e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (4.22e-1)" "unprognostic (2.04e-2)" "unprognostic (5.15e-2)" "unprognostic (1.47e-3)" "unprognostic (2.58e-1)" "prognostic favorable (1.55e-4)" "unprognostic (4.90e-2)" "unprognostic (1.51e-1)" "unprognostic (2.23e-1)" "unprognostic (9.65e-2)" 15.5 51.2 17.8 6.3 18.3 5.8 15.8 18.8 26.9 12.4 18.6 15.8 13.0 10.7 21.2 29.1 13.0 6.0 30.0 17.0 18.8 32.8 103.6 14.9 6.2 22.2 19.0 18.9 23.0 9.8 20.5 4.9 21.3 26.5 7.9 7.3 17.1 6.3 21.1 18.2 14.0 5.6 19.0 12.4 17.7 12.6 18.9 5.5 22.1 16.2 6.5 14.1 14.7 22.9 32.2 22.3 22.2 17.6 8.8 17.7 11.3 7.1 16.2 10.3 10.8 25.8 29.5 21.0 19.9 8.0 19.1 32.9 14.6 54.9 4.6 8.2 60.9 8.6 15.9 42.1 31.3 18.4 7.2 24.0 33.5 22.2 9.7 12.3 9.7 16.4 27.5 15.5 7.3 74.7 16.6 29.2 27.3 3.3 31.6 13.6 8.7 53.9 45.3 30.3 34.1 14.8 15.8 29.2 12.7 6.2 60.5 50.5 5.4 8.6 3.6 6.1 10.4 11.9 9.6 24.0 19.0 22.2 23.9 7.4 7.2 1.0 15.3 10.0 12.2 13.6 11.1 12.1 11.3 17.8 15.2 14.6 1.9 11.2 10.9 9.2 5.8 10.3 17.8 18.3 18.8 26.9 17.0 18.8 22.2 19.0 21.3 19.0 18.9 22.9 25.1 35.3 80.8 9.8 20.4 10.3 33.1 105.6 17.1 32.9 59.6 47.0 52.3 60.1 68.9 42.3 29.2 55.4 15.2 33.6 150.6 49.7 41.3 23.8 10.0 22.1 33.0 34.1 6.4 71.3 37.6 24.7 28.5 16.5 16.5 34.3 28.5 225.3 34.8 104.3 8.5 50.4 71.2 20.4 10.2 82.9 40.4 13.5 26.6 4.7 25.1 30.6 30.9 6.6 21.5 29.7 30.0 30.5 18.1 31.8 61.9 143.6 62.1 29.7 13.1 17.9 26.3 26.0 15.8 44.7 19.7 61.8 16.1 121.1 56.6 30.3 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 2402.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.4;HUVEC TERT2: 12.8;SH-SY5Y: 16.2;U-138 MG: 13.7;WM-115: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 0.7 0.3 4.6 0.3 5.8 0.0 1.8 2.2 5.4 1.7 0.0 0.8 0.1 1.6 0.6 0.4 0.6 2.6 0.8 5.1 3.9 0.1 0.1 0.2 0.2 1.0 1.5 1.0 0.6 0.2 0.5 1.0 1.3 0.9 0.4 0.4 0.3 0.7 0.1 0.2 0.3 1.3 1.4 0.4 0.3 0.4 3.0 0.4 1.0 0.5 0.2 0.9 0.5 3.3 0.0 0.2 7.9 29.4 1.0 2.0 0.0 10.9 1.6 3.0 1.8 0.0 0.1 0.0 0.0 4.9 1.8 0.0 5.8 0.0 3.7 0.0 3.4 0.0 0.0 0.0 2.4 0.0 0.5 1.4 0.0 4.4 1.3 5.4 12.8 0.1 0.0 1.1 1.7 0.0 0.0 0.0 1.7 0.0 3.0 0.3 0.6 0.0 0.6 0.1 0.2 16.2 0.0 0.0 0.2 2.2 1.1 0.0 7.1 13.7 7.7 0.2 4.2 0.0 0.0 0.0 5.7 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 2.2 5.4 5.1 3.9 1.0 1.5 1.3 1.4 3.0 3.3 2.2 0.0 0.0 20.5 0.1 1.1 0.0 0.0 0.6 4.4 0.8 1.4 1.0 0.0 0.0 0.0 2.1 0.1 0.1 0.0 1.9 0.0 6.5 0.5 15.9 5.2 0.0 0.0 443.4 0.0 0.1 16.0 0.0 0.4 0.0 1.9 1.4 0.0 0.4 1.7 300.3 0.0 0.0 0.0 1.6 6.5 0.9 0.4 1.8 10.3 0.0 3.0 0.0 2402.1 13.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.7 2.9 0.0 1.1 0.2 0.1 0.0 0.2 3.4 0.0 0.1 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 90.5;Leydig cells: 98.2;NK-cells: 64.9;Peritubular cells: 177.9" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.3" "Cell line enhanced" "Detected in some" "HHSteC: 4.4;NTERA-2: 2.7;PC-3: 1.9;U-266/70: 3.9" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.19e-2)" "unprognostic (6.31e-2)" "unprognostic (6.70e-3)" "unprognostic (1.29e-1)" "unprognostic (3.99e-2)" "unprognostic (9.31e-2)" "unprognostic (6.94e-2)" "unprognostic (1.20e-1)" "unprognostic (8.06e-2)" "unprognostic (8.37e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.26e-11)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-2)" "unprognostic (6.66e-2)" 7.1 2.8 0.4 0.3 0.5 1.3 4.1 0.1 1.0 16.7 0.0 5.0 1.9 15.4 0.0 2.8 11.0 2.9 15.0 0.3 0.0 3.2 3.3 14.3 1.1 0.4 0.0 29.9 1.6 0.0 5.7 2.8 0.1 11.8 0.1 0.1 1.0 1.1 0.5 3.1 3.4 1.2 0.0 3.0 4.3 5.2 0.1 0.0 2.4 0.0 0.1 11.9 10.9 0.2 0.6 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.4 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.5 0.2 1.2 4.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.4 0.0 0.2 2.7 0.0 1.9 0.9 0.0 1.1 0.0 0.0 0.4 0.2 0.3 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.3 0.0 3.9 0.2 1.1 0.0 0.2 0.1 0.0 0.2 0.0 1.5 0.0 0.9 0.0 0.3 1.0 0.0 0.1 0.0 0.7 0.1 2.2 0.1 11.3 0.3 1.7 0.4 0.5 0.1 1.0 0.3 0.0 0.4 0.0 0.1 0.0 0.1 0.2 2.2 0.0 0.5 1.0 1.1 13.4 0.8 0.7 0.6 1.3 1.7 1.5 9.6 1.5 0.4 1.8 0.0 4.0 27.4 3.0 0.0 1.2 1.0 4.0 3.5 2.2 3.0 2.7 0.3 0.5 2.2 90.5 4.6 1.0 0.0 1.4 12.1 1.0 5.7 3.3 0.6 1.9 4.1 1.0 18.5 6.2 98.2 1.3 19.6 0.0 1.2 0.5 64.9 0.0 0.2 4.3 0.9 177.9 4.3 0.5 2.7 1.0 0.5 7.7 0.0 0.7 5.3 2.1 10.5 0.7 15.8 10.3 8.1 2.1 1.7 0.9 MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Basal respiratory cells: 56.8;Distal enterocytes: 82.0;Paneth cells: 46.2;Proximal enterocytes: 47.2;Urothelial cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 86.9;hTCEpi: 38.3;OE19: 41.7;RT4: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057288, HPA057890" Approved "Nucleoplasm,Focal adhesion sites" "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA057288: , HPA057890: " "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" 14.7 2.0 18.7 0.5 18.1 0.2 8.3 12.1 18.8 4.1 11.9 17.5 1.8 5.2 2.1 13.5 6.1 1.4 3.8 16.2 15.6 1.9 0.3 14.1 0.2 15.2 17.8 1.1 0.8 0.1 1.3 2.0 12.9 5.0 10.5 3.0 2.5 3.5 1.8 23.7 10.2 4.1 14.4 1.1 8.8 22.3 19.3 0.3 5.9 2.4 3.2 16.3 7.6 13.9 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.1 1.5 0.0 0.1 86.9 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.0 4.3 0.0 0.0 1.2 38.3 0.0 3.1 0.7 0.3 0.3 0.0 0.2 0.0 0.3 0.1 0.3 0.0 41.7 0.1 0.8 0.0 0.0 0.0 15.7 0.2 0.7 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.6 0.2 1.0 0.0 0.4 6.3 3.7 0.0 0.9 0.2 0.9 0.0 0.4 18.7 18.1 12.1 18.8 16.2 15.6 15.2 17.8 12.9 14.4 19.3 13.9 31.5 28.9 26.5 47.7 0.4 38.5 5.3 56.8 21.1 2.7 1.0 1.5 1.3 7.2 15.2 7.3 0.0 0.0 0.2 82.0 0.0 1.2 6.7 0.1 0.0 16.8 3.6 0.4 2.8 0.4 0.0 4.4 12.2 0.1 0.0 0.0 17.9 0.0 0.1 1.7 4.8 32.9 2.0 0.0 1.8 13.4 1.2 0.5 3.6 10.3 0.4 9.4 1.0 1.0 0.6 16.7 46.2 3.0 0.1 8.6 47.2 0.8 4.5 0.5 6.6 0.7 5.5 1.1 3.7 34.9 33.1 0.0 1.0 0.1 21.5 43.9 MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 509.9;salivary gland: 267.9;urinary bladder: 211.2" "Cell type enriched" "Detected in many" 8 "Ductal cells: 8176.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 145.9;CAPAN-2: 815.9;EFO-21: 189.8;RPTEC TERT1: 350.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 2810000 35000 "Cluster 5: Breast - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" 3.8 0.1 0.0 2.0 0.0 0.3 168.7 0.0 0.3 13.3 0.0 1.6 0.6 97.4 27.9 21.3 91.2 509.9 0.2 0.0 0.0 140.2 3.4 31.6 1.9 0.0 0.0 0.7 85.2 0.0 0.3 0.8 0.0 54.0 1.0 0.0 267.9 34.9 0.1 32.4 0.6 4.8 0.0 0.2 7.3 0.6 0.4 3.3 0.4 0.0 29.3 211.2 1.7 0.0 0.2 145.9 0.0 0.4 0.0 0.0 0.2 0.0 2.1 0.1 0.1 1.9 815.9 0.0 189.8 0.0 0.0 1.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.6 1.0 0.1 0.2 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.5 11.8 0.0 0.0 0.0 0.0 350.1 1.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.1 0.0 0.7 3.0 0.0 1.6 0.1 0.6 0.4 1.0 5.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 86.6 43.3 0.0 1.5 1.0 382.2 135.4 1.2 0.0 124.2 93.7 0.7 100.1 401.2 1017.0 0.0 0.7 2.9 1.2 0.0 8176.2 6.1 62.1 3.3 8.8 0.0 0.0 0.0 209.4 0.3 3.4 0.0 124.6 2.5 0.0 0.0 0.0 98.0 0.0 0.0 0.0 38.7 0.6 0.3 10.3 11.8 12.6 0.0 0.0 65.2 0.0 0.0 0.0 0.0 850.9 0.0 0.0 0.1 603.3 0.0 33.9 72.6 0.0 0.0 0.0 31.4 0.1 0.2 17.0 2.4 0.8 3.6 0.0 2.3 840.8 MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Endothelial cells: 158.0;Hepatic stellate cells: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cell line enriched" "Detected in some" 13 "HUVEC TERT2: 1242.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" 22.6 3.8 0.8 10.9 0.8 1.8 27.3 0.8 1.1 28.5 1.4 9.9 5.4 15.0 2.8 14.5 23.1 21.1 3.6 0.6 0.9 1.1 8.7 16.1 14.0 1.4 1.4 4.9 3.4 0.5 0.7 40.1 1.2 3.8 14.9 0.5 2.7 4.6 1.1 8.2 13.5 16.8 1.1 0.6 5.2 12.7 1.5 3.7 23.1 6.6 7.6 19.6 9.8 1.1 0.0 0.0 94.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1242.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 43.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 6.3 0.0 2.2 0.2 1.2 0.8 0.8 0.8 1.1 0.6 0.9 1.4 1.4 1.2 1.1 1.5 1.1 15.4 0.0 12.0 0.3 2.3 4.2 0.1 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.6 0.0 0.0 0.0 3.9 0.0 1.9 0.0 17.7 0.3 0.7 158.0 0.0 25.9 0.2 0.0 0.0 1.9 0.0 0.4 2.5 0.1 146.3 2.4 0.6 0.0 0.1 0.0 0.0 5.7 5.9 7.7 0.3 9.1 1.8 21.5 0.7 0.8 2.1 0.0 0.4 0.0 0.0 0.0 5.0 0.4 0.0 0.0 1.5 0.4 0.0 0.3 0.9 15.4 0.0 0.8 4.5 0.0 1.6 0.0 0.0 0.1 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MMS22L "C6orf167, dJ39B17.2" ENSG00000146263 "MMS22 like, DNA repair protein" Q6ZRQ5 6 97142161-97283217 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 67.8;Oligodendrocytes: 52.3;Spermatocytes: 56.9;Spermatogonia: 45.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA067042 Supported Nucleoplasm NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA067042: AB_2685768" "unprognostic (3.61e-2)" "unprognostic (2.80e-1)" "unprognostic (2.26e-2)" "unprognostic (1.97e-3)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.00e-5)" "unprognostic (9.63e-2)" "unprognostic (5.81e-3)" "unprognostic (8.21e-3)" "unprognostic (9.39e-2)" "unprognostic (6.58e-2)" "unprognostic (1.34e-6)" "unprognostic (3.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" 1.1 1.1 0.7 2.0 1.8 7.0 2.3 1.3 1.2 1.6 0.7 1.6 1.2 1.5 0.5 1.7 1.4 1.0 0.7 0.7 1.0 0.8 0.9 1.1 3.4 2.1 1.4 1.4 1.3 1.4 0.5 2.0 1.8 1.3 2.3 2.4 1.0 0.8 0.6 2.9 1.6 1.5 1.2 1.4 1.1 6.8 1.5 5.2 1.1 0.5 3.4 1.3 1.1 2.4 7.5 8.2 13.5 14.8 2.2 4.0 10.6 15.0 6.9 13.8 20.1 11.4 8.6 16.4 9.0 5.7 16.0 13.4 17.1 8.3 27.4 14.1 12.7 16.7 11.3 7.2 1.3 25.8 11.3 2.2 4.3 19.5 9.0 2.8 6.0 15.2 23.1 25.6 13.1 8.9 9.5 10.4 5.2 12.1 6.1 15.8 12.8 5.8 5.9 9.7 7.7 6.6 9.8 4.9 4.0 7.6 7.6 15.7 4.5 14.0 13.3 11.8 20.8 3.2 10.3 18.3 8.0 16.0 15.7 0.5 0.4 0.9 0.6 0.7 1.0 0.5 0.9 1.0 1.1 0.7 0.8 1.1 0.4 0.6 1.6 1.2 0.9 0.4 0.7 1.8 1.3 1.2 0.7 1.0 2.1 1.4 1.8 1.2 1.5 2.4 5.9 3.2 8.6 16.6 9.7 9.2 5.8 4.0 4.0 11.6 6.1 6.2 4.2 5.7 6.9 3.7 41.7 12.5 14.6 3.3 1.9 2.9 67.8 4.4 6.1 6.5 1.2 26.3 11.3 4.1 11.2 6.1 7.7 2.8 7.6 24.0 10.8 3.1 6.4 3.3 7.7 8.4 8.2 7.5 6.0 17.2 9.9 6.8 7.2 36.5 6.4 6.1 6.2 22.6 52.3 3.0 2.0 5.7 13.1 2.9 5.4 0.8 6.1 31.9 6.6 7.9 5.1 56.9 45.8 7.1 8.2 3.6 9.6 5.2 10.3 3.0 MND1 GAJ ENSG00000121211 "Meiotic nuclear divisions 1" Q9BWT6 4 153344649-153415118 "Predicted intracellular proteins" "DNA recombination, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.3;lymphoid tissue: 26.7;testis: 15.9" "Cell type enhanced" "Detected in many" "Early spermatids: 25.9;Erythroid cells: 30.9;Spermatocytes: 55.5;Spermatogonia: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;T-reg: 1.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043499 Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA043499: AB_2732506" "unprognostic (2.21e-2)" "unprognostic (6.46e-3)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (2.97e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (6.21e-3)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.28e-2)" "unprognostic (1.28e-2)" "unprognostic (9.43e-2)" "unprognostic (2.71e-8)" "unprognostic (7.65e-2)" "unprognostic (5.70e-2)" "unprognostic (9.84e-2)" "unprognostic (7.64e-2)" 0.5 0.5 1.1 4.7 1.2 13.3 2.5 1.0 2.0 0.7 0.7 4.4 3.0 0.7 1.2 3.3 0.5 1.0 0.4 1.1 1.3 0.6 1.3 0.8 12.0 1.4 1.1 0.3 0.3 0.0 0.3 2.4 1.2 0.5 5.1 0.0 0.9 0.9 1.3 2.1 2.6 1.5 1.1 1.8 1.6 15.9 1.3 26.7 0.4 0.5 14.0 1.3 1.3 1.7 38.6 17.7 52.7 30.6 0.7 7.2 20.9 35.1 15.4 31.4 25.6 32.8 26.1 74.4 5.8 8.5 29.5 15.7 52.3 15.8 39.9 47.7 19.9 39.1 17.3 42.9 1.1 88.2 17.9 1.9 3.3 24.4 21.1 7.8 10.7 86.0 71.0 91.9 26.8 21.5 124.1 116.0 39.1 17.9 17.8 74.1 18.2 35.8 19.3 9.7 26.5 23.3 15.7 17.7 30.0 26.5 14.7 72.1 2.6 24.1 34.8 28.1 32.6 79.0 96.0 58.8 24.1 69.6 28.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 1.3 0.0 0.3 0.0 0.0 0.4 0.0 0.1 1.7 0.1 1.1 1.2 1.0 2.0 1.1 1.3 1.4 1.1 1.2 1.1 1.3 1.7 0.2 0.0 0.5 2.6 1.9 2.8 1.8 5.1 0.0 0.0 2.2 4.6 0.6 2.8 0.7 0.0 0.0 14.5 1.0 4.1 1.9 0.3 25.9 3.5 1.6 1.3 0.0 30.9 1.6 0.5 20.6 3.6 2.0 5.7 0.0 11.8 1.4 1.0 12.5 0.0 2.6 4.3 4.1 2.5 5.0 20.5 0.9 2.4 3.6 1.9 0.1 0.0 1.0 2.0 23.3 0.6 1.6 2.2 7.7 1.2 0.7 0.1 1.0 0.0 6.6 0.9 8.6 55.5 96.3 10.2 1.4 2.5 2.5 1.5 10.3 2.7 MOB2 HCCA2 ENSG00000182208 "MOB kinase activator 2" Q70IA6 11 1469457-1501247 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046313 Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoli "Nucleoplasm, Cytosol" "HPA046313: AB_10959882" "unprognostic (5.02e-1)" "unprognostic (5.71e-2)" "unprognostic (6.24e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (4.64e-4)" "unprognostic (8.30e-2)" "unprognostic (1.06e-3)" "unprognostic (3.06e-2)" "unprognostic (1.77e-1)" "unprognostic (2.80e-2)" "unprognostic (5.30e-2)" "unprognostic (2.87e-1)" "prognostic favorable (2.02e-4)" "unprognostic (2.67e-1)" "unprognostic (8.56e-2)" "unprognostic (9.78e-2)" "unprognostic (1.15e-1)" 32.3 19.6 34.7 19.2 36.3 24.2 28.3 37.8 39.7 27.4 36.2 61.1 18.0 30.7 36.5 51.9 34.4 27.8 43.5 35.3 36.5 18.6 20.0 24.7 26.8 36.1 36.8 28.1 32.8 34.9 11.2 25.7 36.5 32.5 34.8 14.6 35.2 42.3 50.9 50.0 28.6 49.0 36.1 25.1 27.9 14.2 37.1 34.1 24.2 70.4 27.0 39.9 31.6 37.8 29.3 31.2 18.3 15.7 44.2 30.8 17.1 22.5 30.9 40.4 31.8 20.1 39.0 20.9 16.7 50.6 26.0 34.8 28.1 48.6 24.3 28.8 44.3 16.0 11.7 26.2 30.2 21.2 24.2 25.1 57.9 21.9 25.3 32.7 43.6 27.0 26.3 21.2 20.7 20.6 27.4 37.7 23.0 54.3 29.4 19.9 19.0 22.2 34.4 26.9 34.6 37.3 27.3 34.0 27.9 23.0 15.9 21.3 37.7 25.6 13.1 8.3 14.5 21.6 22.3 21.8 17.9 20.3 19.8 9.7 8.7 11.9 16.2 9.2 13.6 8.1 14.1 13.7 10.6 11.0 11.6 10.2 7.1 12.1 13.4 7.5 15.3 10.6 34.7 36.3 37.8 39.7 35.3 36.5 36.1 36.8 36.5 36.1 37.1 37.8 84.8 6.4 10.0 6.5 20.2 82.2 30.1 39.4 12.0 18.4 27.8 33.3 14.8 12.8 18.4 7.3 12.5 31.1 64.5 58.6 27.4 33.5 24.3 18.9 17.7 58.2 20.9 36.2 15.2 38.5 31.0 23.3 16.8 29.2 24.8 20.3 33.9 9.0 26.4 43.7 10.9 32.8 32.6 18.2 39.3 12.1 23.9 28.1 56.9 11.2 29.4 21.5 81.4 6.6 14.8 39.6 63.2 51.1 17.0 48.6 54.3 23.9 12.9 21.4 85.5 20.8 68.3 29.8 41.1 13.7 82.0 59.4 36.4 20.2 27.7 37.6 MOGAT1 "DGAT2L, DGAT2L1, MGAT1" ENSG00000124003 "Monoacylglycerol O-acyltransferase 1" Q96PD6 2 222671658-222709930 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "gallbladder: 16.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Breast glandular cells: 7.2;Cholangiocytes: 7.2;Endometrial ciliated cells: 3.9;Exocrine glandular cells: 5.1;Glandular and luminal cells: 4.9;Hepatocytes: 3.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049944, HPA076308" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "Endoplasmic reticulum" "HPA049944: AB_2680964, HPA076308: " "unprognostic (6.32e-2)" "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (4.28e-3)" "unprognostic (4.39e-2)" "unprognostic (4.32e-2)" "unprognostic (9.44e-2)" "unprognostic (1.91e-1)" "unprognostic (8.59e-2)" "unprognostic (3.07e-3)" "unprognostic (4.99e-2)" "unprognostic (3.89e-1)" "unprognostic (9.03e-3)" 0.9 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.0 16.8 0.4 0.1 0.1 0.8 3.1 0.4 0.0 0.1 0.6 0.0 0.2 0.6 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.1 0.4 0.6 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.3 0.7 7.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.9 3.9 0.6 0.1 0.0 0.0 2.5 5.1 0.0 0.1 0.0 4.9 0.0 0.2 0.0 3.2 0.9 0.0 1.9 0.0 0.0 0.3 0.3 0.1 0.0 1.3 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.9 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 MOGAT2 "DGAT2L5, FLJ22644, MGAT2" ENSG00000166391 "Monoacylglycerol O-acyltransferase 2" Q3SYC2 11 75717838-75732958 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "intestine: 48.2;liver: 25.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 73.8;Hepatocytes: 79.6;Intestinal goblet cells: 36.2;Proximal enterocytes: 159.6;Undifferentiated cells: 32.4" "Cancer enhanced" "Detected in many" "liver cancer: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Hep G2: 4.5;RPMI-8226: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028834 Uncertain NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA028834: AB_10601865" "unprognostic (5.63e-2)" "unprognostic (2.71e-2)" "unprognostic (6.37e-2)" "unprognostic (6.88e-3)" "unprognostic (1.15e-4)" "unprognostic (2.66e-3)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (4.21e-2)" "unprognostic (3.02e-1)" "unprognostic (1.24e-5)" "unprognostic (2.13e-3)" "unprognostic (1.84e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-3)" 0.0 0.0 0.0 1.9 0.2 0.0 1.4 0.0 0.1 0.1 0.0 13.9 44.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 25.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 12.6 0.0 0.2 0.2 0.0 0.6 48.2 0.7 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.6 0.3 1.5 0.2 0.0 0.0 0.0 0.0 73.8 0.0 0.0 0.0 0.1 0.0 0.0 2.4 2.7 0.0 0.5 0.0 0.0 2.6 0.1 0.0 0.0 0.4 79.6 0.0 0.0 0.0 36.2 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 21.3 0.0 0.0 0.6 159.6 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.4 0.1 MORC4 "FLJ11565, ZCW4, ZCWCC2" ENSG00000133131 "MORC family CW-type zinc finger 4" Q8TE76 X 106813871-107000212 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 79.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 131.4;Alveolar cells type 2: 130.4;Cytotrophoblasts: 329.8;Syncytiotrophoblasts: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000395, HPA015547, HPA050250" Enhanced Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA000395: AB_1079405, HPA015547: AB_2669216, HPA050250: AB_2681063" "prognostic unfavorable (3.56e-5)" "unprognostic (3.30e-3)" "unprognostic (1.09e-1)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (6.29e-3)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (5.56e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-1)" "unprognostic (1.60e-2)" "unprognostic (6.57e-2)" "unprognostic (4.89e-2)" "unprognostic (8.69e-2)" 13.4 30.9 24.8 7.8 35.5 11.8 12.2 47.8 51.0 12.1 17.8 8.5 10.4 11.5 16.3 9.6 10.4 10.1 7.0 32.4 22.4 10.8 21.1 8.8 5.6 11.1 11.4 17.4 15.1 11.7 6.2 79.9 16.6 12.4 10.8 22.3 10.9 11.5 20.2 18.7 10.0 11.4 3.9 6.0 8.4 20.2 16.6 5.6 10.2 10.3 7.0 7.5 11.1 55.7 29.8 121.0 11.4 26.4 35.0 40.3 60.5 28.7 30.8 14.6 18.3 64.6 13.1 3.7 14.2 30.5 23.9 22.5 39.8 25.5 17.1 4.6 23.0 6.4 40.7 27.1 25.6 4.7 13.9 20.8 24.3 19.6 28.6 85.7 13.1 4.1 3.9 41.4 32.7 26.7 10.7 6.4 8.9 82.0 45.2 4.2 22.9 4.3 47.0 23.3 9.2 11.5 35.4 33.9 23.0 15.9 19.7 5.0 12.6 22.5 21.4 44.7 15.7 11.1 16.2 11.5 24.0 3.8 16.2 8.3 1.5 1.8 1.9 1.3 1.7 1.7 1.9 1.5 0.7 2.7 2.1 1.7 3.7 1.5 1.7 2.5 1.5 0.4 24.8 35.5 47.8 51.0 32.4 22.4 11.1 11.4 16.6 3.9 16.6 55.7 8.6 131.4 130.4 6.2 5.1 17.5 19.1 4.9 21.1 5.4 11.5 9.5 3.0 10.0 61.8 5.5 4.2 329.8 10.4 3.6 21.5 9.9 0.9 6.2 11.5 13.6 1.8 0.4 4.2 7.4 28.2 33.4 10.2 15.5 66.3 10.3 7.5 24.0 23.4 1.7 6.5 10.5 6.1 2.1 5.0 1.8 11.1 8.2 12.4 3.7 0.3 6.7 3.1 15.1 8.7 7.5 6.7 11.7 5.8 16.4 4.4 12.7 62.2 7.2 26.3 16.9 12.0 9.9 26.6 19.7 16.1 257.8 11.9 10.1 10.1 11.8 MORN3 ENSG00000139714 "MORN repeat containing 3" Q6PF18 12 121648742-121672631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.1;fallopian tube: 3.9;testis: 4.5" "Cell type enriched" "Detected in many" 6 "Late spermatids: 2271.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 9 "BEWO: 13.6;CACO-2: 8.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA038709, HPA038710" Uncertain Approved Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA038709: AB_2676164, HPA038710: AB_2676165" "prognostic favorable (1.16e-4)" "unprognostic (2.70e-3)" "unprognostic (5.56e-2)" "unprognostic (5.13e-2)" "unprognostic (7.38e-3)" "unprognostic (3.46e-3)" "unprognostic (7.44e-2)" "unprognostic (3.70e-2)" "unprognostic (4.31e-2)" "unprognostic (3.09e-2)" "unprognostic (3.65e-3)" "unprognostic (3.11e-2)" "unprognostic (1.39e-2)" "unprognostic (3.06e-1)" "unprognostic (2.21e-1)" "unprognostic (8.85e-2)" "unprognostic (1.18e-1)" 0.2 0.3 1.4 0.5 1.6 0.9 0.4 1.3 1.6 0.4 4.1 0.2 0.2 0.3 0.5 0.1 3.9 0.4 0.2 1.5 1.5 0.7 0.1 1.0 1.2 1.7 2.2 0.3 0.3 2.3 1.3 0.8 1.1 0.2 0.2 0.6 0.4 0.3 0.2 2.0 0.4 0.2 1.3 0.7 0.6 4.5 1.6 0.9 0.6 0.0 0.6 0.2 0.2 1.4 0.2 0.1 0.4 0.2 0.0 0.3 13.6 0.2 0.1 0.0 0.1 8.3 0.4 0.2 0.2 0.1 0.2 0.5 0.1 0.2 0.1 0.1 0.1 0.6 0.5 0.5 0.2 0.5 0.9 0.1 0.3 0.4 0.0 0.1 0.3 1.0 0.2 0.3 0.1 0.3 0.9 0.7 0.3 0.0 0.1 0.4 0.0 0.1 0.5 0.2 1.2 1.1 0.1 0.2 0.0 0.6 1.1 0.1 0.2 0.2 0.2 0.4 0.2 0.2 0.1 0.4 1.0 0.4 0.2 1.3 0.3 0.1 0.7 0.1 0.8 0.3 0.8 0.4 0.1 0.5 0.7 0.5 1.2 0.9 0.3 0.5 0.8 0.2 1.4 1.6 1.3 1.6 1.5 1.5 1.7 2.2 1.1 1.3 1.6 1.4 1.1 3.2 1.3 0.0 1.6 3.2 1.2 3.3 0.0 1.3 2.5 1.8 1.4 4.3 8.2 1.8 0.0 0.5 6.6 0.0 7.9 4.4 352.0 34.1 1.2 2.1 0.0 0.0 2.7 1.4 0.7 1.4 0.0 3.0 2.5 2.5 0.7 0.0 0.9 0.0 2.3 0.0 4.1 0.0 0.3 2271.5 9.3 1.7 0.0 0.0 1.8 5.4 5.2 0.0 0.1 2.2 0.0 9.4 3.5 0.7 0.1 1.1 51.7 2.2 0.0 1.5 1.4 8.7 6.7 0.0 4.0 7.3 6.7 3.4 0.2 1.1 MOV10 "fSAP113, gb110, MGC2948" ENSG00000155363 "Mov10 RISC complex RNA helicase" Q9HCE1 1 112673141-112700746 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031627 Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA031627: AB_2673966" "unprognostic (1.44e-2)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" "unprognostic (6.82e-3)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.44e-4)" "unprognostic (9.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.58e-3)" "unprognostic (2.85e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.48e-11)" "unprognostic (4.01e-2)" "unprognostic (3.61e-1)" "unprognostic (1.46e-3)" "unprognostic (1.21e-3)" 7.6 13.2 3.4 9.7 3.7 4.7 7.6 2.9 3.4 10.2 4.7 10.9 22.1 10.2 9.5 13.2 13.5 9.4 5.2 3.1 6.2 10.3 19.4 9.1 8.5 4.7 4.1 9.7 8.2 12.8 11.2 23.6 4.0 11.5 10.7 3.0 14.3 11.2 3.1 27.2 20.2 10.8 4.1 12.1 10.7 16.6 5.4 16.2 9.8 4.2 7.0 9.3 10.8 3.4 29.5 17.9 10.4 40.2 8.3 23.5 39.1 19.8 46.5 56.9 80.7 33.2 31.7 0.0 13.2 27.4 21.1 30.5 39.7 47.4 19.6 32.4 24.2 20.2 26.7 37.8 35.3 8.5 19.3 39.9 14.2 34.6 10.9 37.4 49.2 40.7 27.2 9.8 17.8 54.7 32.7 6.6 23.4 12.2 18.1 57.9 26.2 1.3 26.4 31.9 4.4 15.0 40.9 27.5 31.5 20.2 21.4 19.4 29.7 17.6 31.0 12.4 17.8 11.3 3.3 0.1 34.9 17.4 51.4 0.9 3.5 0.7 12.5 10.3 12.4 2.1 10.8 11.1 6.8 1.5 10.3 8.0 1.1 12.7 12.2 1.0 10.2 7.6 3.4 3.7 2.9 3.4 3.1 6.2 4.7 4.1 4.0 4.1 5.4 3.4 13.0 9.6 10.5 26.4 6.3 8.8 10.4 15.5 8.0 2.4 7.8 7.0 4.1 8.6 17.4 16.5 0.0 54.7 5.6 29.2 3.9 15.5 5.9 5.8 7.3 16.9 15.0 3.8 4.1 15.5 18.4 9.4 23.9 7.0 1.3 36.5 16.8 18.3 15.8 5.0 2.3 18.0 12.2 7.5 6.0 6.2 9.3 10.3 3.6 12.2 14.4 15.1 10.3 18.1 3.3 12.4 26.9 7.5 3.6 11.1 46.2 13.9 18.4 1.1 13.1 4.0 7.4 2.7 3.4 11.7 7.0 38.2 9.2 22.4 15.5 12.1 MPDZ MUPP1 ENSG00000107186 "Multiple PDZ domain crumbs cell polarity complex component" O75970 9 13105706-13279692 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 85.7" "Cell type enhanced" "Detected in many" "Astrocytes: 121.5;Excitatory neurons: 213.6;Inhibitory neurons: 271.3;Oligodendrocyte precursor cells: 158.8;Oligodendrocytes: 279.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 58.1;HUVEC TERT2: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013512, HPA020255, HPA026686" Enhanced NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB013512: AB_2533517, HPA020255: AB_1854073, HPA026686: AB_1854074" "unprognostic (1.55e-1)" "unprognostic (4.21e-3)" "unprognostic (4.09e-3)" "unprognostic (1.68e-1)" "unprognostic (4.28e-2)" "unprognostic (1.03e-1)" "prognostic favorable (8.68e-4)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.50e-1)" "prognostic favorable (7.40e-4)" "unprognostic (1.54e-1)" "unprognostic (2.59e-3)" "unprognostic (1.32e-3)" "unprognostic (2.50e-1)" "unprognostic (1.58e-1)" "unprognostic (9.74e-2)" 22.7 9.9 18.0 5.3 23.2 0.2 13.2 20.3 20.6 14.3 21.7 16.1 2.8 17.8 15.3 7.6 17.5 11.7 29.8 18.0 20.4 18.8 85.7 11.1 3.9 19.8 22.4 25.6 4.6 11.3 10.7 24.7 20.3 19.2 5.3 33.0 6.3 23.2 19.9 3.8 6.4 18.6 21.4 11.1 7.6 11.5 17.7 4.3 11.7 31.3 1.8 12.6 9.9 35.3 16.1 21.2 58.1 26.0 39.2 35.4 11.8 15.9 16.4 13.8 13.1 0.0 0.0 0.0 4.5 39.6 14.2 0.3 17.3 8.8 22.3 0.0 10.2 10.5 21.9 3.9 20.8 0.1 5.4 26.5 3.6 9.7 6.6 35.3 53.5 0.0 0.3 0.1 12.5 4.2 0.0 0.2 24.9 0.0 9.0 0.0 14.2 0.0 13.7 8.5 7.2 26.9 12.6 2.8 15.5 39.7 8.1 0.1 42.8 14.1 2.7 4.7 12.4 0.0 0.0 0.0 6.8 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 23.2 20.3 20.6 18.0 20.4 19.8 22.4 20.3 21.4 17.7 35.3 70.9 32.1 7.9 121.5 0.2 5.1 10.1 4.8 3.4 30.9 8.6 15.6 109.7 1.5 14.7 7.3 39.6 16.1 0.4 0.1 1.9 4.2 4.2 27.0 12.4 44.6 1.8 2.1 213.6 2.0 22.9 27.4 1.5 6.3 1.3 39.5 42.5 74.4 5.8 26.9 271.3 0.2 6.1 0.6 6.8 3.7 24.2 0.9 17.8 60.9 0.6 40.2 0.0 158.8 279.6 1.8 0.0 33.8 0.1 12.9 0.0 16.4 36.6 25.4 39.5 35.1 40.8 6.7 13.9 0.1 4.0 10.8 0.8 7.6 0.0 4.7 MPP7 FLJ32798 ENSG00000150054 "Membrane palmitoylated protein 7" Q5T2T1 10 28050993-28334486 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.1" "Cell type enhanced" "Detected in many" "Early spermatids: 82.3;Excitatory neurons: 76.7;Suprabasal keratinocytes: 61.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 23.3;CACO-2: 45.2;CAPAN-2: 27.9;T-47d: 89.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037597, HPA037598" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" Nucleoplasm "HPA037597: AB_2675569, HPA037598: AB_10696941" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "unprognostic (6.64e-2)" "unprognostic (7.78e-2)" "unprognostic (9.31e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.79e-14)" "unprognostic (2.46e-1)" "unprognostic (1.88e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" 3.8 2.7 0.1 5.7 1.0 8.8 9.7 4.7 2.2 6.4 0.1 10.7 6.0 5.1 1.9 37.1 11.8 6.4 6.6 0.4 0.0 12.2 1.9 10.1 2.6 0.0 0.0 3.4 12.1 11.8 2.2 11.7 0.1 8.0 9.3 9.7 7.6 4.8 13.8 24.8 7.2 8.7 0.0 2.4 8.8 9.0 0.0 3.2 14.4 14.3 6.9 9.7 9.6 1.1 5.9 0.1 0.6 0.0 0.1 0.1 23.3 1.2 0.9 4.7 7.4 45.2 27.9 0.0 0.3 3.4 3.4 10.4 3.9 7.5 10.9 0.0 7.5 0.0 1.3 2.8 0.0 0.0 0.0 0.3 11.6 0.7 0.4 0.0 0.0 2.2 1.1 0.0 6.2 10.9 2.3 0.0 1.4 8.9 2.1 1.2 13.3 0.0 0.4 19.0 1.1 0.0 2.3 11.3 0.0 3.6 89.3 1.1 0.0 1.8 12.5 0.0 1.0 0.2 0.0 0.1 0.1 10.7 0.0 0.0 7.7 9.0 3.8 2.5 5.6 0.6 4.2 2.6 7.8 0.5 7.9 5.7 3.1 5.0 1.5 0.1 1.1 5.1 0.1 1.0 4.7 2.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.1 1.6 44.8 48.3 10.4 5.5 23.1 10.9 9.5 7.4 1.1 14.7 8.6 12.1 10.0 24.3 14.7 16.7 50.0 9.8 15.3 9.8 5.5 82.3 9.3 0.6 11.7 6.7 4.2 76.7 12.9 3.5 2.6 11.2 6.6 1.3 0.7 2.9 3.2 5.4 3.3 30.3 10.4 8.2 4.7 5.3 20.3 0.9 8.1 7.2 12.2 16.2 24.0 4.1 4.5 2.5 6.6 7.8 0.4 5.1 7.5 12.1 9.5 19.3 8.5 0.0 1.5 7.6 5.4 9.5 48.0 61.1 46.5 16.3 0.1 11.3 17.4 MPV17L "FLJ39599, MLPH1, MLPH2, MPV17L1" ENSG00000156968 "MPV17 mitochondrial inner membrane protein like" Q2QL34 16 15395754-15413271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 14.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 29.5;SK-BR-3: 8.2" "Low region specificity" "Detected in all" HPA041180 Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041180: AB_10794266" "unprognostic (9.65e-2)" "unprognostic (8.74e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (2.73e-1)" "unprognostic (4.38e-3)" "unprognostic (8.41e-2)" "unprognostic (8.99e-3)" "unprognostic (8.70e-2)" "unprognostic (6.36e-3)" "prognostic favorable (1.48e-11)" "unprognostic (2.84e-1)" "unprognostic (7.60e-2)" "unprognostic (6.61e-3)" "unprognostic (3.87e-2)" 1.8 2.5 1.2 1.8 0.1 4.4 6.4 1.9 2.2 2.8 0.0 2.3 3.4 2.0 0.3 1.0 1.8 2.4 1.6 0.1 0.0 3.3 9.1 0.9 2.3 0.1 0.0 2.1 14.1 2.4 3.2 0.6 0.3 2.0 1.0 4.4 7.1 1.8 8.0 4.5 2.3 0.8 0.0 1.8 1.8 1.0 0.5 0.2 2.2 2.4 0.6 1.9 1.3 0.4 1.0 1.9 0.8 0.8 0.2 0.1 1.2 0.5 0.0 0.0 0.0 1.9 3.4 1.5 1.3 0.6 0.5 1.5 3.0 0.0 0.0 1.2 0.8 5.9 4.6 3.9 0.3 3.6 29.5 0.3 0.4 0.1 0.2 0.5 0.0 1.6 2.3 3.3 0.1 1.9 1.4 2.3 1.7 0.3 0.1 2.0 0.6 1.6 0.5 0.8 4.8 1.6 2.7 8.2 0.2 0.9 1.8 2.6 2.6 1.3 0.8 1.1 1.1 1.4 0.6 1.7 0.7 1.7 0.5 1.7 1.2 0.2 0.8 0.9 0.6 0.8 0.5 0.8 0.4 1.2 0.4 0.8 1.8 1.1 0.4 0.7 0.4 0.6 1.2 0.1 1.9 2.2 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.4 2.5 6.4 8.8 3.9 2.0 7.9 14.4 8.2 0.0 12.8 11.4 6.0 6.0 14.3 13.1 0.0 10.4 0.5 4.1 2.7 15.6 7.5 4.6 5.4 9.2 6.6 1.2 2.1 5.6 12.9 0.5 8.1 2.0 10.7 6.3 7.6 4.2 29.1 1.0 8.4 5.9 8.7 2.0 13.6 20.6 0.8 7.2 6.0 21.4 2.8 0.7 6.2 0.0 7.5 3.2 5.9 15.3 14.3 1.4 9.6 9.3 19.9 21.0 16.6 0.0 23.5 6.7 9.0 2.0 0.6 11.5 0.5 9.9 4.4 12.1 10.1 MPZL3 ENSG00000160588 "Myelin protein zero like 3" Q6UWV2 11 118226690-118252365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.3;skin 1: 30.4" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 43.8;Suprabasal keratinocytes: 63.9;T-cells: 44.3;Urothelial cells: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 6 "basophil: 44.3;eosinophil: 99.4;MAIT T-cell: 28.9;neutrophil: 87.8" "Group enriched" "Detected in all" 8 "granulocytes: 99.4;T-cells: 28.9" "Cell line enhanced" "Detected in many" "CAPAN-2: 26.3;HMC-1: 29.0;MCF7: 17.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA029116 Approved "Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA029116: AB_10610142" "unprognostic (2.54e-2)" "unprognostic (1.24e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (3.13e-3)" "unprognostic (1.52e-1)" "unprognostic (8.74e-3)" "unprognostic (2.86e-2)" "unprognostic (9.82e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (4.98e-4)" "unprognostic (4.86e-2)" "unprognostic (1.58e-2)" "unprognostic (1.89e-1)" "unprognostic (3.90e-1)" "prognostic favorable (3.64e-4)" "unprognostic (1.20e-1)" 3.3 0.5 0.7 4.7 1.0 7.3 8.2 2.8 0.7 11.5 1.7 5.6 5.4 1.5 4.9 33.3 5.4 7.6 1.6 0.7 0.8 3.1 7.5 7.9 4.8 1.0 0.7 0.5 7.2 6.7 3.8 0.8 0.9 5.6 6.1 1.3 11.7 2.7 1.7 30.4 5.3 1.5 0.7 6.0 6.8 1.1 0.8 2.8 6.1 0.9 12.6 4.4 16.8 0.7 5.0 0.6 0.0 0.7 0.0 0.0 0.7 0.6 0.1 0.1 0.1 16.7 26.3 4.9 12.5 0.0 1.9 6.8 1.2 5.6 0.1 0.3 2.0 3.0 1.4 8.1 0.2 4.1 29.0 0.3 13.6 0.0 5.4 0.0 8.8 3.3 3.8 2.7 0.1 17.1 1.9 2.2 2.4 16.5 1.2 0.0 0.0 7.4 10.0 6.2 3.4 0.3 6.6 8.6 0.5 1.3 15.4 2.2 4.3 0.1 1.3 0.1 0.1 0.4 5.1 3.1 0.1 0.1 0.3 44.3 6.0 99.4 7.0 3.7 28.9 1.7 11.3 9.6 8.1 1.9 8.4 6.9 87.8 8.2 2.6 1.1 8.4 5.3 0.7 1.0 2.8 0.7 0.7 0.8 1.0 0.7 0.9 0.7 0.8 0.7 2.4 16.0 26.9 0.0 4.9 35.6 21.7 11.8 9.6 0.3 28.2 14.7 1.7 5.7 15.9 9.2 2.1 0.6 9.6 19.6 0.0 10.5 7.4 32.7 4.1 4.9 12.0 0.4 2.2 8.8 0.7 1.6 18.3 34.0 1.3 0.1 2.2 8.2 1.3 0.0 2.3 5.1 14.2 5.1 18.7 7.7 0.0 5.5 10.6 1.9 3.8 0.3 4.1 0.5 0.3 16.7 9.1 0.4 6.6 30.6 9.3 1.1 43.8 1.7 0.0 0.4 2.3 1.7 0.8 14.3 63.9 1.6 44.3 0.2 8.1 46.4 MRAS "M-RAs, R-RAS3, RRAS3" ENSG00000158186 "Muscle RAS oncogene homolog" O14807 3 138347648-138405534 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 202.3;heart muscle: 132.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 121.7;Distal tubular cells: 58.7;Theca cells: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "non-classical monocyte: 25.0" "Lineage enriched" "Detected in many" 9 "monocytes: 25.0" "Cell line enhanced" "Detected in many" "BJ: 92.9;EFO-21: 113.7;fHDF/TERT166: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042728 Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol Vesicles "HPA042728: AB_10796582" "unprognostic (1.96e-1)" "unprognostic (2.95e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.69e-1)" "unprognostic (5.32e-2)" "unprognostic (8.96e-2)" "unprognostic (3.85e-3)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (3.18e-3)" "unprognostic (1.78e-2)" "unprognostic (6.25e-2)" "unprognostic (2.21e-1)" "unprognostic (4.23e-2)" 91.9 67.7 112.7 10.8 130.6 1.7 46.7 118.2 105.5 17.3 48.9 24.2 3.3 28.7 7.1 7.9 26.4 12.0 132.9 105.6 132.8 22.9 5.5 18.4 5.2 126.1 135.9 48.6 5.7 8.2 17.7 10.6 112.9 15.3 4.1 15.9 13.4 15.0 80.4 12.2 8.7 23.2 110.3 12.2 12.0 9.6 202.3 4.9 26.4 48.0 3.3 29.1 12.1 97.8 0.8 7.9 15.8 24.5 59.6 29.2 40.0 92.9 16.0 7.3 8.2 3.3 3.1 0.3 113.7 70.4 18.6 0.1 9.0 1.8 6.1 7.7 3.1 0.5 4.8 20.1 15.9 0.0 1.9 41.5 5.9 0.7 1.4 13.6 1.3 0.0 10.7 0.8 31.4 3.7 0.0 20.4 19.1 0.0 2.7 1.1 33.8 0.2 30.4 2.0 18.6 42.0 62.8 0.7 45.9 10.9 16.1 37.7 0.6 23.7 25.3 24.3 2.4 0.1 1.0 1.2 21.4 0.1 11.4 0.2 2.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.3 0.8 25.0 0.1 0.0 0.8 112.7 130.6 118.2 105.5 105.6 132.8 126.1 135.9 112.9 110.3 202.3 97.8 8.9 9.6 1.5 54.2 0.8 2.2 3.0 3.4 1.2 5.6 28.8 34.8 121.7 2.8 3.5 9.2 10.4 20.1 0.2 0.0 58.7 8.6 11.6 1.0 21.4 14.5 1.8 0.0 25.5 3.2 3.2 23.0 2.0 1.5 6.3 35.2 12.8 1.6 26.3 28.6 20.6 0.0 2.0 15.1 18.4 40.0 23.3 18.2 28.4 20.6 12.2 24.3 0.0 28.6 11.0 3.8 0.0 34.3 0.1 3.3 0.0 27.5 1.3 9.6 6.6 20.8 18.9 7.3 18.6 0.4 1.0 14.4 0.8 59.1 0.0 0.6 MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 122.3" "Group enriched" "Detected in many" 4 "Breast glandular cells: 128.9;Hepatic stellate cells: 397.7;Hofbauer cells: 176.1;Kupffer cells: 361.4;Macrophages: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Group enriched" "Detected in some" 19 "MOLT-4: 19.3;TIME: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" 54.4 28.7 0.8 24.0 1.7 0.7 16.3 0.3 3.5 17.2 9.2 16.1 9.9 7.2 1.7 13.1 11.9 27.7 10.2 1.1 0.7 7.6 40.9 122.3 15.2 1.4 0.9 6.2 8.1 4.6 1.5 54.3 1.1 2.2 18.5 0.1 4.9 8.0 1.8 2.8 17.5 30.3 0.7 50.6 9.7 7.5 2.8 8.0 5.5 8.7 3.0 29.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 19.3 0.0 0.2 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 1.7 0.3 3.5 1.1 0.7 1.4 0.9 1.1 0.7 2.8 1.3 4.0 32.1 43.5 1.3 3.5 0.4 0.0 0.0 0.0 0.0 128.9 1.7 3.6 11.5 7.4 0.0 0.0 0.9 1.0 1.4 0.0 0.1 27.3 0.0 0.1 39.0 0.0 3.2 0.8 0.4 1.4 2.5 0.0 0.1 13.9 0.1 397.7 13.1 176.1 0.0 1.3 0.9 0.0 361.4 46.8 19.4 1.5 316.5 0.0 60.9 0.5 0.0 0.0 0.5 0.5 0.1 1.5 0.0 1.0 0.0 2.2 0.1 5.8 0.0 32.9 3.0 2.2 0.4 2.3 1.2 0.4 2.1 4.7 1.7 0.8 0.1 MRGPRX2 MRGX2 ENSG00000183695 "MAS related GPR family member X2" Q96LB1 11 19054455-19060717 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Cell type enhanced" "Detected in single" "Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055220 Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA055220: AB_2682743" "unprognostic (1.56e-2)" "unprognostic (1.79e-1)" 0.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MRM3 "FLJ10581, HC90, RMTL1, RNMTL1" ENSG00000171861 "Mitochondrial rRNA methyltransferase 3" Q9HC36 17 782353-792509 "Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 27.1;Distal tubular cells: 19.6;Ductal cells: 18.9;Exocrine glandular cells: 18.4;Extravillous trophoblasts: 24.6;Proximal tubular cells: 20.0;Syncytiotrophoblasts: 19.6;Theca cells: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022534, HPA023031, HPA023292" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA022534: AB_1856386, HPA023031: AB_1856387, HPA023292: AB_1856388" "unprognostic (1.66e-1)" "unprognostic (5.83e-3)" "unprognostic (6.72e-2)" "prognostic favorable (2.81e-4)" "unprognostic (2.67e-1)" "unprognostic (1.83e-1)" "unprognostic (2.48e-1)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (8.20e-2)" "unprognostic (3.72e-3)" "unprognostic (8.47e-2)" "prognostic favorable (3.00e-4)" "unprognostic (3.82e-2)" "unprognostic (9.98e-2)" "unprognostic (1.05e-2)" "unprognostic (1.42e-2)" 9.3 12.9 7.9 6.8 8.4 17.6 8.7 9.9 9.2 6.7 9.7 9.7 7.8 7.6 5.2 11.6 8.0 4.8 17.3 8.2 7.9 9.7 20.5 6.0 10.4 8.2 8.7 8.7 19.6 9.1 6.2 6.9 8.6 7.5 7.5 4.3 9.5 6.0 29.4 14.7 8.2 6.6 7.7 9.9 13.0 18.6 8.6 8.3 7.0 18.7 9.3 8.6 7.2 8.3 26.4 53.9 11.3 19.8 16.2 13.8 22.5 13.6 12.8 27.3 22.8 31.8 12.0 47.3 14.1 10.6 13.1 21.7 33.0 12.0 24.8 16.2 55.9 18.3 30.6 27.9 16.7 15.8 16.0 16.7 16.2 29.0 23.9 13.6 20.7 28.3 31.3 20.1 14.5 28.5 27.5 20.8 16.9 19.3 28.2 33.1 7.9 25.3 18.2 14.2 15.1 17.6 19.8 16.6 26.5 9.0 20.6 14.2 16.6 14.6 11.2 21.0 38.3 8.0 11.8 18.9 18.3 22.1 20.0 12.5 24.6 14.7 25.0 20.6 27.0 38.2 27.1 30.8 25.8 38.4 32.8 28.4 1.8 32.7 21.1 20.8 31.9 26.8 7.9 8.4 9.9 9.2 8.2 7.9 8.2 8.7 8.6 7.7 8.6 8.3 11.3 6.4 1.1 0.0 4.2 0.0 0.0 0.0 0.0 0.0 9.8 10.4 0.0 0.0 1.3 5.5 0.0 27.1 7.6 0.0 19.6 18.9 0.0 8.3 8.0 5.1 0.0 0.0 0.0 18.4 24.6 4.1 0.0 8.8 3.8 15.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.5 0.0 0.0 20.0 0.7 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 19.6 4.4 28.9 0.0 0.0 MRPL19 "KIAA0104, MRP-L15, RLX1, RPML15" ENSG00000115364 "Mitochondrial ribosomal protein L19" P49406 2 75646783-75690851 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 167.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046805, HPA056622" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046805: AB_2679816, HPA056622: AB_2683195" "unprognostic (9.24e-2)" "unprognostic (3.84e-2)" "prognostic favorable (7.39e-4)" "unprognostic (8.40e-2)" "unprognostic (1.59e-2)" "unprognostic (7.52e-3)" "unprognostic (5.75e-2)" "unprognostic (9.86e-2)" "unprognostic (6.21e-3)" "unprognostic (9.71e-3)" "prognostic unfavorable (1.97e-5)" "unprognostic (2.42e-1)" "unprognostic (3.67e-2)" "unprognostic (1.55e-1)" "unprognostic (3.30e-1)" "unprognostic (1.12e-1)" "unprognostic (1.20e-1)" 31.3 30.1 21.8 18.9 27.4 13.9 28.6 26.5 23.5 29.1 14.8 27.8 23.7 21.7 25.2 25.0 18.1 20.7 35.0 18.8 26.7 56.0 63.7 17.8 20.3 23.4 24.4 17.4 23.6 45.2 12.2 25.7 25.4 21.6 30.9 19.3 24.1 25.1 66.4 23.9 19.9 29.0 26.8 16.9 18.4 16.5 24.9 24.3 36.9 44.8 25.1 24.5 15.1 32.5 100.7 57.5 53.3 48.3 57.0 68.1 75.6 63.4 57.0 78.5 62.2 88.5 40.6 56.5 62.1 69.2 73.8 69.5 83.7 95.8 117.8 63.2 72.4 77.4 44.4 114.3 61.0 82.9 44.5 45.6 72.4 79.7 72.3 49.6 84.1 60.8 86.4 32.3 78.5 61.9 76.1 64.9 69.9 102.9 65.2 94.5 116.5 74.5 134.1 61.9 58.8 50.2 62.2 71.2 72.4 53.3 61.1 32.8 57.0 68.3 75.4 61.2 94.6 33.3 53.8 47.1 53.9 81.0 61.1 17.7 20.2 14.2 22.1 26.8 25.1 26.8 22.7 23.8 29.7 22.7 19.9 24.6 1.4 24.4 24.9 35.0 26.5 17.2 21.8 27.4 26.5 23.5 18.8 26.7 23.4 24.4 25.4 26.8 24.9 32.5 31.8 19.2 29.6 10.7 27.4 29.1 28.6 77.8 21.1 38.3 32.4 29.5 40.2 25.8 49.4 49.7 52.1 90.3 26.3 24.0 125.2 88.7 27.6 42.7 48.4 27.7 27.6 32.8 13.9 61.1 87.3 33.7 36.7 50.3 19.0 35.8 27.1 67.6 47.3 48.8 14.3 36.5 44.7 14.6 17.0 11.2 35.4 23.7 33.8 12.2 35.0 39.6 34.0 15.1 20.0 53.6 27.7 36.5 36.5 36.1 36.5 167.7 32.8 50.9 19.7 31.4 38.1 55.5 17.6 44.3 28.3 57.7 25.3 62.2 50.7 35.6 MRPS30 "PAP, PDCD9" ENSG00000112996 "Mitochondrial ribosomal protein S30" Q9NP92 5 44808947-44820428 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018686, HPA021149" Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA018686: AB_1854127, HPA021149: AB_1854128" "unprognostic (1.56e-1)" "unprognostic (1.23e-1)" "unprognostic (4.48e-1)" "unprognostic (2.94e-2)" "unprognostic (5.47e-2)" "unprognostic (3.54e-2)" "prognostic unfavorable (5.91e-4)" "unprognostic (1.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.15e-1)" "unprognostic (1.05e-1)" "unprognostic (2.45e-2)" "prognostic favorable (2.87e-9)" "unprognostic (2.20e-2)" "unprognostic (5.04e-1)" "unprognostic (7.01e-2)" "unprognostic (8.70e-3)" 13.1 13.4 4.0 8.5 6.3 25.3 14.1 7.3 9.0 9.5 2.6 13.8 13.4 10.3 5.9 16.6 10.5 5.8 24.5 6.2 2.1 15.1 21.4 8.5 11.7 0.5 1.9 9.4 12.9 12.7 6.4 7.5 1.1 8.7 10.8 6.4 11.6 6.4 35.6 20.5 12.0 7.3 1.9 11.3 12.0 11.5 3.5 10.1 12.0 26.7 9.6 11.4 10.9 7.6 33.2 32.5 19.2 36.9 14.0 16.3 61.9 16.2 17.4 22.8 16.1 51.9 40.5 50.4 55.1 10.7 52.6 30.6 37.7 24.2 20.3 32.7 64.5 37.5 67.8 40.8 31.1 51.5 29.8 16.2 24.4 23.9 29.4 17.2 21.7 27.4 58.5 45.6 21.4 28.3 33.3 67.7 32.4 26.0 57.6 31.3 32.1 67.6 34.6 24.1 29.3 22.9 75.1 40.1 52.2 14.5 36.2 38.0 21.4 26.8 39.6 22.3 51.0 24.4 31.0 41.0 22.6 68.4 27.7 26.0 24.0 18.7 30.9 27.2 32.3 37.8 34.2 34.2 25.6 31.7 40.0 33.9 4.4 35.2 33.3 19.4 46.1 33.6 4.0 6.3 7.3 9.0 6.2 2.1 0.5 1.9 1.1 1.9 3.5 7.6 22.1 25.6 16.5 4.6 31.7 48.8 38.8 63.3 26.7 31.3 23.6 21.1 60.2 17.2 31.5 5.5 18.8 40.0 37.6 21.4 33.2 36.5 105.1 21.3 29.4 23.9 28.7 18.7 14.4 33.1 38.0 24.1 21.4 22.5 19.0 24.1 17.9 26.9 32.5 32.0 8.0 24.5 30.5 16.6 15.7 14.3 20.8 18.9 17.8 3.7 26.3 20.4 26.8 3.5 6.9 29.6 22.8 18.0 20.1 27.6 25.6 35.4 21.9 26.3 13.1 24.9 28.7 43.4 26.4 28.6 75.0 18.6 32.6 32.6 37.0 42.3 MS4A2 "APY, FCER1B, IGER, MS4A1" ENSG00000149534 "Membrane spanning 4-domains A2" Q01362 11 60088261-60098467 "FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.6" "Cell type enriched" "Detected in some" 20 "granulocytes: 967.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 908 "basophil: 275.5" "Lineage enriched" "Detected in single" 1467 "granulocytes: 275.5" "Cell line enhanced" "Detected in some" "HEL: 2.7;THP-1: 1.3" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 15.3" HPA059967 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "HPA059967: AB_2684183" "unprognostic (7.28e-2)" "unprognostic (9.21e-2)" "unprognostic (2.50e-4)" "unprognostic (4.97e-2)" "unprognostic (4.47e-1)" "unprognostic (2.40e-6)" "unprognostic (1.88e-2)" "unprognostic (6.21e-3)" "unprognostic (3.96e-1)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (6.63e-3)" "unprognostic (6.49e-3)" "unprognostic (9.95e-2)" "unprognostic (4.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.74e-1)" 2.6 0.2 0.3 2.4 0.3 0.9 2.7 0.5 0.5 6.3 0.6 4.9 5.5 4.2 3.7 4.8 0.9 8.2 0.6 0.3 0.3 0.5 0.4 12.6 1.1 0.4 0.3 0.1 0.5 0.3 0.1 0.3 0.4 3.0 5.4 0.0 1.8 2.4 2.9 2.5 6.7 4.1 0.3 0.2 5.3 1.0 0.3 1.2 0.1 1.2 1.8 3.8 2.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 275.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.4 0.3 0.3 0.5 0.5 0.3 0.3 0.4 0.3 0.4 0.3 0.3 0.5 0.1 0.0 30.9 0.0 0.3 0.0 0.9 0.0 0.0 0.3 0.1 0.1 0.5 0.0 6.8 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.4 0.1 0.1 0.3 0.0 46.7 0.1 0.0 0.1 1.1 0.0 0.1 967.4 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.0 0.7 0.4 0.0 0.7 0.2 0.1 0.1 0.0 0.0 0.0 12.2 0.0 0.0 0.2 MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 63.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 376.8;Kupffer cells: 445.0;Macrophages: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 82.9;plasmacytoid DC: 27.7" "Group enriched" "Detected in many" 30 "dendritic cells: 27.7;monocytes: 82.9" "Cell line enhanced" "Detected in some" "HEL: 35.6;HMC-1: 45.8;K-562: 154.9" HPA029323 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" 42.8 24.7 3.5 16.5 3.6 6.1 12.3 3.7 8.6 14.1 4.4 14.0 5.2 4.9 3.4 8.9 11.6 25.8 8.4 3.5 3.9 4.8 15.4 28.0 31.3 4.2 3.4 4.1 4.0 3.3 3.3 63.1 3.6 3.4 16.1 2.0 7.6 4.9 2.3 2.9 13.5 20.0 2.5 33.3 6.6 3.0 5.5 11.5 3.7 10.4 7.5 28.0 3.3 4.3 0.3 0.1 0.1 0.6 0.0 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.9 0.8 0.4 0.0 0.4 0.3 0.5 0.1 0.6 1.6 0.0 35.6 0.7 0.6 0.1 1.2 45.8 0.4 0.3 0.2 0.8 0.2 0.0 0.4 154.9 4.2 0.6 0.7 0.6 0.9 0.7 0.3 0.1 0.7 0.0 2.5 0.1 1.5 0.5 0.5 0.3 0.3 0.1 0.7 0.7 8.9 0.8 1.5 0.6 0.4 0.2 6.0 0.7 0.5 0.2 0.8 0.2 0.1 9.9 0.0 0.1 61.2 0.2 1.0 0.1 0.1 27.6 0.3 0.2 0.1 0.9 1.8 82.9 27.7 0.1 6.0 3.5 3.6 3.7 8.6 3.5 3.9 4.2 3.4 3.6 2.5 5.5 4.3 2.3 0.0 7.9 0.0 3.0 1.8 0.1 0.0 0.6 0.0 0.3 2.2 3.4 2.8 2.5 0.0 0.0 1.8 7.5 0.0 0.0 0.0 0.7 0.0 0.0 5.7 0.0 13.0 0.1 0.0 2.0 1.6 0.0 0.0 7.6 0.0 47.5 4.6 376.8 0.0 0.1 0.0 0.0 445.0 24.9 1.0 0.9 264.6 3.6 10.3 8.3 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 13.1 1.2 1.1 0.1 0.2 0.7 1.8 3.6 1.5 0.1 0.0 0.1 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 MSH3 "DUP, MRP1" ENSG00000113318 "MutS homolog 3" P20585 5 80654652-80876815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 95.1;Inhibitory neurons: 98.9;Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036081 Approved "Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear bodies" "HPA036081: AB_10673229" "unprognostic (1.91e-1)" "unprognostic (7.61e-2)" "prognostic favorable (5.90e-5)" "unprognostic (2.95e-2)" "unprognostic (1.89e-1)" "unprognostic (6.41e-2)" "unprognostic (1.81e-1)" "unprognostic (8.70e-2)" "unprognostic (3.17e-2)" "unprognostic (2.62e-2)" "unprognostic (2.63e-1)" "unprognostic (3.91e-1)" "prognostic favorable (1.77e-4)" "unprognostic (5.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" 9.4 4.6 1.8 4.3 2.4 5.0 5.5 1.6 2.0 6.6 1.5 6.0 6.0 5.2 5.3 5.0 7.0 5.7 4.9 1.7 2.0 12.5 11.4 4.2 4.9 1.7 2.0 5.3 5.2 8.8 3.3 4.3 1.7 5.2 6.2 3.7 4.5 5.2 5.1 5.1 5.6 5.1 2.2 4.1 5.0 3.9 2.5 7.1 10.8 4.7 6.1 6.3 3.9 2.0 12.4 15.0 11.7 13.1 6.6 12.3 16.6 12.2 11.8 13.6 16.7 10.0 15.6 22.2 14.0 15.3 12.8 10.4 15.6 20.5 17.3 14.2 13.9 8.4 13.4 9.9 6.8 9.9 8.5 10.9 9.5 15.8 16.6 13.8 12.9 7.9 12.1 12.9 16.1 11.9 19.0 4.7 9.0 4.8 7.7 13.2 24.2 16.4 15.2 13.0 11.6 13.9 10.4 11.5 13.0 14.4 15.2 9.4 12.4 7.8 9.5 6.2 23.0 8.7 15.6 21.6 12.2 16.8 10.2 0.7 2.9 1.9 3.3 3.4 3.8 3.4 3.5 3.6 3.3 2.2 2.6 2.6 1.7 3.1 4.6 2.8 4.8 2.4 1.8 2.4 1.6 2.0 1.7 2.0 1.7 2.0 1.7 2.2 2.5 2.0 16.7 35.3 9.3 66.9 18.1 10.5 12.3 12.4 12.5 25.8 19.4 12.8 17.6 8.6 14.3 14.7 14.6 18.9 18.7 18.2 15.6 12.4 14.6 28.4 20.2 12.0 14.5 17.0 95.1 10.3 12.9 15.9 31.6 18.9 8.2 19.9 10.0 20.1 11.5 21.9 98.9 13.2 8.2 13.0 7.0 17.2 13.7 16.3 3.6 72.1 19.9 22.5 19.6 71.9 92.3 10.6 9.6 25.9 22.0 6.5 16.8 43.6 65.4 28.3 19.7 20.2 14.7 24.7 25.5 22.3 10.1 13.1 25.4 14.7 17.4 10.7 MSL2 "FLJ10546, KIAA1585, msl-2, MSL2L1, RNF184" ENSG00000174579 "MSL complex subunit 2" Q9HCI7 3 136148917-136197241 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003413 Uncertain Approved Nucleoplasm,Cytosol NA No "Cluster 32: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "HPA003413: AB_1848659" "unprognostic (9.86e-2)" "prognostic favorable (4.80e-4)" "unprognostic (1.30e-1)" "unprognostic (2.32e-1)" "unprognostic (4.41e-2)" "unprognostic (8.11e-3)" "unprognostic (1.37e-2)" "unprognostic (4.62e-2)" "unprognostic (7.01e-2)" "unprognostic (1.36e-1)" "unprognostic (1.71e-1)" "unprognostic (2.54e-2)" "unprognostic (2.23e-1)" "unprognostic (5.79e-3)" "unprognostic (4.54e-2)" "unprognostic (3.52e-2)" "unprognostic (1.76e-3)" 11.9 9.4 6.0 21.3 8.7 57.9 13.8 18.8 8.6 14.7 5.0 12.9 13.3 15.2 9.2 12.7 15.5 12.8 9.5 6.3 7.3 11.3 14.1 14.5 33.1 6.5 7.2 20.9 11.5 15.3 8.0 13.1 9.2 12.0 12.7 14.8 13.0 11.5 12.6 11.4 14.8 12.1 6.0 25.8 14.7 17.4 7.2 60.3 17.0 17.2 31.7 13.3 10.1 12.1 26.5 7.5 20.8 23.2 14.4 15.6 33.1 16.1 16.0 14.9 14.9 19.4 15.0 52.1 21.2 14.3 17.0 20.4 24.6 16.2 23.5 25.3 11.9 59.6 19.8 11.0 14.8 51.7 26.1 12.6 17.7 11.7 34.0 14.2 15.1 48.1 22.0 47.7 12.5 15.8 93.8 26.7 25.3 14.7 13.1 40.5 33.5 35.3 7.1 21.2 25.2 16.8 37.7 16.1 26.5 16.2 14.7 28.5 20.6 19.0 15.0 17.4 15.1 47.5 28.0 78.7 15.9 20.2 13.2 5.1 2.5 4.1 5.1 2.9 6.2 3.1 4.7 6.0 2.7 5.4 9.6 6.4 5.9 5.1 2.2 1.5 3.9 4.2 6.0 8.7 18.8 8.6 6.3 7.3 6.5 7.2 9.2 6.0 7.2 12.1 15.0 19.2 11.2 18.9 30.4 28.0 15.6 5.6 23.3 12.9 15.8 9.5 15.2 8.6 7.0 12.9 4.2 8.9 47.1 9.3 3.9 5.1 4.1 9.6 15.3 13.9 18.0 23.1 28.0 5.6 6.3 14.7 9.2 12.9 7.0 12.6 16.8 23.4 8.5 16.8 31.6 14.1 2.0 24.2 25.4 3.7 9.3 18.9 21.4 37.5 21.4 8.0 30.9 39.2 55.1 6.4 5.6 8.6 27.8 14.5 7.7 7.4 5.7 9.7 6.6 18.6 12.3 16.0 12.5 22.8 26.7 4.8 36.2 8.5 12.2 14.0 MSLN "CAK1, MPF" ENSG00000102854 Mesothelin Q13421 16 760734-768865 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 93.4;fallopian tube: 278.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Alveolar cells type 2: 85.6;Club cells: 121.9;Glandular and luminal cells: 57.1;Paneth cells: 214.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 343.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.9" "Group enriched" "Detected in many" 39 "dendritic cells: 5.9;monocytes: 1.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 513.4;EFO-21: 77.4;HeLa: 173.4;hTCEpi: 111.5;OE19: 96.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "spinal cord: 1.7" "CAB002216, HPA017172" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "CAB002216: AB_563874, HPA017172: AB_1853819" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (3.95e-2)" "unprognostic (2.46e-1)" "unprognostic (9.47e-2)" "unprognostic (8.57e-2)" "unprognostic (4.69e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.63e-1)" "prognostic favorable (5.91e-4)" "unprognostic (2.00e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-2)" "unprognostic (3.35e-2)" 93.4 0.2 0.7 1.1 1.0 3.2 0.5 0.6 1.5 15.9 0.3 8.9 7.1 6.2 24.1 7.1 278.2 16.4 8.4 0.7 0.8 6.5 0.2 71.8 0.2 1.9 1.2 3.7 0.9 0.1 0.7 2.7 1.3 3.8 4.0 0.7 39.3 9.9 0.0 1.4 2.9 3.4 1.0 0.4 13.0 1.1 1.2 0.8 0.2 0.0 27.2 2.9 2.9 1.0 0.4 2.1 0.0 1.0 0.0 0.0 2.3 0.3 7.7 8.7 2.0 7.4 513.4 0.0 77.4 0.7 0.1 1.3 0.0 0.7 0.7 0.2 0.3 0.0 173.4 5.9 4.4 0.2 0.1 0.0 111.5 0.0 2.0 7.8 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.1 0.6 96.4 0.8 0.2 0.2 0.6 2.4 0.1 0.1 0.0 29.7 0.1 0.0 0.1 0.7 0.0 0.0 0.4 12.1 0.1 0.0 0.3 0.3 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.3 0.7 1.0 0.6 1.5 0.7 0.8 1.9 1.2 1.3 1.0 1.2 1.0 0.0 189.1 85.6 0.0 0.0 0.3 3.0 49.0 0.0 1.4 0.3 0.3 1.6 52.9 121.9 25.8 0.0 0.2 0.0 4.1 0.0 9.3 1.6 35.8 3.3 0.7 3.0 0.0 0.0 0.9 0.0 4.6 0.0 57.1 0.0 0.0 0.4 0.1 2.9 0.0 0.0 1.6 22.4 1.0 1.9 7.4 4.7 3.7 1.8 1.0 4.4 0.0 0.0 0.0 0.0 33.0 214.4 0.0 1.4 3.3 1.7 0.1 54.2 0.6 0.0 0.0 2.8 0.6 0.7 0.5 0.1 0.1 1.3 0.0 3.1 50.8 MSMO1 "DESP4, ERG25, SC4MOL" ENSG00000052802 "Methylsterol monooxygenase 1" Q15800 4 165327667-165343164 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 575.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 532.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 416.2;Karpas-707: 412.3;RPTEC TERT1: 399.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055073, HPA056127" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA055073: , HPA056127: AB_2683045" "unprognostic (5.76e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.35e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (7.14e-2)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (9.21e-4)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.54e-1)" "unprognostic (1.40e-1)" 18.3 95.2 36.7 20.9 48.2 10.4 66.2 45.1 47.5 57.1 37.4 39.2 75.7 19.1 97.0 145.7 20.9 21.7 18.5 43.9 59.2 52.6 575.6 70.3 20.7 90.5 58.4 25.7 22.6 42.9 18.4 22.9 78.6 58.9 32.9 26.1 34.7 12.1 5.5 82.5 38.1 16.5 45.0 11.0 31.5 52.8 48.4 13.4 22.4 6.5 27.0 20.2 67.0 61.1 89.1 21.7 198.8 36.4 97.7 312.0 37.5 35.3 159.0 44.7 123.4 41.5 372.9 43.4 20.6 43.1 416.2 71.7 101.6 366.3 49.4 37.7 63.0 20.0 20.0 127.6 194.9 35.8 26.8 192.6 237.6 163.6 100.6 61.1 58.8 55.7 35.3 412.3 74.6 45.7 32.6 58.2 115.6 46.9 21.0 16.8 21.8 132.3 399.5 102.5 39.7 30.0 54.5 77.9 33.9 121.7 36.1 44.7 67.6 20.6 36.1 18.5 24.7 75.9 86.5 58.6 43.9 36.0 28.5 13.7 8.6 8.8 34.0 11.6 25.4 40.6 31.8 31.4 15.0 37.6 34.3 35.6 6.1 24.9 20.5 19.3 31.0 29.2 36.7 48.2 45.1 47.5 43.9 59.2 90.5 58.4 78.6 45.0 48.4 61.1 16.9 51.3 168.0 70.5 28.9 36.1 70.1 189.2 21.6 33.8 81.9 23.0 10.7 40.0 160.0 69.9 27.1 55.6 20.7 130.8 35.2 67.9 6.4 27.6 12.2 30.4 60.7 53.9 33.6 71.7 87.0 24.1 35.2 44.4 47.7 83.0 27.8 532.0 28.3 35.3 22.8 72.8 170.9 28.0 11.5 7.0 24.8 18.3 32.0 10.3 23.6 27.2 17.5 42.7 49.6 86.8 85.7 18.8 10.9 138.3 46.0 38.4 103.2 50.4 19.7 5.6 35.1 8.7 15.4 84.6 115.1 123.0 22.3 136.1 36.9 129.0 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.3;stomach 1: 42.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Distal enterocytes: 53.9;Gastric mucus-secreting cells: 108.6;Intestinal goblet cells: 25.7;Pancreatic endocrine cells: 31.2;Paneth cells: 30.3;Proximal enterocytes: 27.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 39.3;CAPAN-2: 98.8;HaCaT: 56.3;HBEC3-KT: 59.4;hTCEpi: 83.4;RT4: 67.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" 5.1 0.3 1.1 5.1 1.1 0.2 3.8 1.1 1.7 5.7 1.3 26.5 25.2 1.3 1.2 17.5 1.7 11.4 3.2 1.1 0.9 3.4 1.1 9.5 2.5 0.9 0.8 1.0 5.8 0.1 2.7 0.8 0.9 4.7 20.1 0.2 5.4 1.0 1.3 62.3 23.9 2.0 0.8 1.6 42.6 8.4 0.9 8.8 3.4 0.7 5.6 9.2 11.5 1.0 39.3 14.4 0.1 0.6 0.0 0.0 2.2 0.5 0.1 0.0 0.0 4.1 98.8 1.7 8.8 0.5 0.1 56.3 0.0 59.4 0.0 0.9 1.0 0.1 25.9 0.9 0.9 0.0 1.2 0.3 83.4 0.2 11.7 0.2 0.1 0.2 0.8 0.3 0.0 5.1 0.1 0.1 0.3 33.1 34.6 2.9 0.0 1.1 35.8 67.9 1.0 0.1 11.5 22.6 0.2 0.1 17.7 0.9 0.3 0.0 0.3 0.3 0.1 0.5 0.2 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 1.1 1.1 1.7 1.1 0.9 0.9 0.8 0.9 0.8 0.9 1.0 1.6 25.6 10.3 0.7 1.0 8.8 2.2 14.2 6.8 0.0 2.8 2.5 1.0 0.0 10.6 0.0 0.0 0.1 0.2 53.9 0.0 6.4 15.4 2.9 0.8 0.6 4.2 0.0 1.1 10.0 0.4 0.8 108.6 5.3 0.0 0.1 0.0 0.0 0.1 0.0 1.1 25.7 2.0 0.0 1.4 10.5 0.3 0.5 0.0 1.0 0.6 0.0 1.0 2.0 0.1 31.2 30.3 0.0 0.5 2.2 27.6 0.1 7.6 0.0 0.0 0.5 0.9 1.3 1.5 3.2 4.7 0.0 0.5 0.0 20.1 6.2 MT1M "MT1, MT1K" ENSG00000205364 "Metallothionein 1M" Q8N339 16 56632659-56633981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 398.9;liver: 562.4" "Cell type enhanced" "Detected in many" "Adipocytes: 1333.5;Distal enterocytes: 906.4;Glandular and luminal cells: 1180.5;Hepatocytes: 1549.5;Paneth cells: 1204.8;Proximal enterocytes: 933.2;Smooth muscle cells: 680.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RPTEC TERT1: 181.8" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.83e-2)" "unprognostic (2.49e-1)" "unprognostic (2.10e-2)" "unprognostic (3.10e-2)" "unprognostic (4.19e-3)" "unprognostic (7.73e-2)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.13e-4)" "unprognostic (4.67e-2)" "unprognostic (3.10e-1)" "unprognostic (3.55e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-2)" "unprognostic (4.71e-2)" 398.9 27.7 214.3 32.8 233.5 0.1 145.6 240.4 316.0 31.2 183.0 134.0 21.2 14.8 4.1 83.4 95.4 42.6 36.6 207.3 219.5 47.6 562.4 116.5 4.5 225.3 226.8 16.1 145.8 2.6 10.4 2.7 232.6 57.5 140.9 24.7 31.5 6.7 48.2 44.6 113.6 37.3 217.6 7.7 98.5 3.9 246.4 5.2 64.3 4.0 2.5 33.4 26.1 213.6 0.0 0.0 0.0 0.0 39.1 27.3 0.5 1.2 9.9 1.2 2.4 0.4 0.6 0.0 7.9 6.3 0.0 0.0 31.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.2 0.1 3.1 0.0 14.8 0.0 23.7 0.0 0.0 0.0 0.0 19.6 0.0 0.1 0.2 13.4 0.0 1.3 0.0 0.1 0.2 181.8 0.0 0.2 0.5 0.0 0.0 0.0 1.7 0.0 2.7 5.5 0.1 0.0 1.8 0.0 0.1 0.0 0.2 4.7 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 214.3 233.5 240.4 316.0 207.3 219.5 225.3 226.8 232.6 217.6 246.4 213.6 1333.5 12.8 7.2 49.6 9.3 27.5 19.0 3.1 27.9 0.0 13.7 52.7 7.9 121.5 6.0 14.7 0.0 0.3 4.9 906.4 37.2 58.9 0.1 413.6 114.7 141.3 32.7 131.0 0.1 117.0 70.5 308.1 25.5 1180.5 15.9 11.9 82.8 1549.5 1.7 0.0 0.1 397.5 0.0 65.9 39.9 1.5 47.8 35.2 88.9 5.6 24.3 0.0 0.0 6.0 0.3 64.1 1204.8 12.0 29.4 152.4 933.2 258.6 5.2 0.0 78.9 587.1 680.1 0.0 0.5 4.7 20.2 1.0 15.5 1.2 559.6 7.9 MTA2 "MTA1-L1, MTA1L1" ENSG00000149480 "Metastasis associated 1 family member 2" O94776 11 62593214-62601865 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 34.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005315, HPA006214, CAB017522, HPA072727" Supported Enhanced Nucleoplasm NA NA 10000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "CAB005315: AB_2146965, CAB017522: AB_831564, HPA006214: AB_1079421, HPA072727: " "unprognostic (5.97e-3)" "unprognostic (1.63e-2)" "unprognostic (1.23e-1)" "unprognostic (3.04e-2)" "unprognostic (3.48e-1)" "unprognostic (3.66e-2)" "prognostic unfavorable (4.82e-5)" "unprognostic (3.32e-3)" "unprognostic (1.95e-1)" "unprognostic (5.38e-3)" "unprognostic (3.09e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-3)" "unprognostic (3.16e-3)" "unprognostic (9.84e-2)" "unprognostic (2.23e-1)" "unprognostic (2.50e-2)" 41.6 34.4 44.4 46.2 46.7 60.7 35.7 45.7 45.3 40.2 38.2 40.0 31.0 37.2 28.7 79.3 33.4 32.6 29.7 44.3 44.1 31.9 30.3 37.8 70.1 49.0 46.1 37.8 23.0 30.2 31.8 39.1 49.4 37.0 47.4 119.8 37.3 36.7 21.2 74.7 40.1 43.8 46.1 60.7 33.9 30.4 45.8 90.2 26.8 24.1 91.8 51.7 47.2 52.7 97.1 83.4 129.8 171.1 57.0 53.2 88.8 80.0 112.3 157.5 114.7 79.7 82.7 137.0 84.0 106.3 84.3 127.2 177.2 222.1 132.8 136.4 87.9 146.4 91.2 81.0 88.3 167.2 180.0 59.6 122.6 111.3 164.1 74.8 148.3 140.4 164.2 106.1 114.6 189.0 213.9 212.1 112.3 91.7 95.1 201.5 92.4 160.6 112.1 143.4 102.9 94.2 83.5 118.2 67.6 102.4 138.9 113.2 104.5 87.9 80.4 100.4 94.0 78.3 109.4 191.8 64.4 120.4 86.9 7.3 7.2 9.9 18.6 12.6 15.6 13.9 15.2 13.5 11.8 10.0 14.0 14.3 3.1 12.1 16.4 13.8 13.5 6.7 44.4 46.7 45.7 45.3 44.3 44.1 49.0 46.1 49.4 46.1 45.8 52.7 22.9 3.2 3.9 2.3 16.9 13.4 4.2 4.2 34.1 0.0 11.3 7.9 3.7 1.5 4.9 1.8 0.0 15.3 16.5 12.1 5.9 5.1 0.8 5.2 10.0 12.0 12.0 20.8 1.5 9.5 8.3 8.6 15.3 9.5 10.8 7.5 13.2 8.2 8.9 0.0 1.6 11.9 4.1 12.8 7.6 0.7 5.0 8.9 1.8 2.8 8.9 0.0 9.2 2.0 2.7 9.7 8.2 4.1 24.1 4.2 6.6 2.7 0.9 0.0 0.0 8.2 11.7 5.9 5.2 32.5 11.2 18.9 18.1 13.6 12.2 4.5 MTA3 KIAA1266 ENSG00000057935 "Metastasis associated 1 family member 3" Q9BTC8 2 42494569-42756947 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 137.0;Oligodendrocyte precursor cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039433 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Vesicles "HPA039433: AB_10794747" "unprognostic (5.40e-2)" "unprognostic (4.89e-2)" "unprognostic (5.28e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (4.13e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (7.55e-2)" "unprognostic (2.04e-1)" "unprognostic (5.43e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-1)" "unprognostic (2.64e-2)" "unprognostic (9.03e-2)" "unprognostic (2.05e-1)" "unprognostic (3.47e-1)" "unprognostic (1.28e-2)" 11.8 41.8 16.4 5.6 18.9 1.6 14.9 9.1 19.4 18.5 7.1 16.6 7.8 16.8 27.5 21.8 16.1 10.0 12.4 21.9 14.9 13.6 7.9 8.8 10.7 12.3 13.9 29.2 18.8 17.3 15.1 15.3 18.8 14.4 13.2 9.3 13.6 16.8 9.1 19.1 11.4 12.0 11.7 7.8 16.8 21.0 16.1 70.4 12.6 9.9 14.5 15.3 17.8 14.8 13.0 16.6 20.1 14.3 17.4 28.0 46.6 7.4 18.6 21.7 19.2 22.2 26.2 45.4 12.6 22.1 15.9 8.2 51.6 25.2 34.2 14.1 21.0 6.7 8.8 36.4 21.9 5.0 29.0 29.5 29.1 13.4 16.6 28.1 30.4 23.9 16.5 6.1 25.7 27.8 30.3 22.0 84.4 20.8 9.7 18.4 18.9 0.0 25.7 12.1 12.3 37.1 13.5 45.5 17.8 61.6 23.2 7.0 14.2 8.9 12.1 7.2 8.1 11.5 4.7 63.5 12.6 5.7 11.1 2.5 0.9 0.0 1.7 0.6 2.6 1.2 2.0 2.9 1.5 1.3 4.4 3.0 0.2 1.8 0.9 0.4 1.1 1.5 16.4 18.9 9.1 19.4 21.9 14.9 12.3 13.9 18.8 11.7 16.1 14.8 12.7 12.8 12.5 60.4 10.8 15.3 21.1 33.0 15.4 0.0 24.6 19.6 12.5 15.7 25.7 22.0 0.0 58.5 5.1 19.1 17.6 22.9 10.7 44.5 23.1 13.1 9.6 2.5 137.0 28.0 42.0 21.7 31.1 32.3 12.0 72.3 20.7 13.3 12.4 0.0 81.8 20.0 50.8 6.6 7.1 26.0 33.8 5.2 17.8 53.4 6.9 0.0 9.2 106.1 65.9 20.2 21.8 39.9 10.9 17.7 25.2 33.1 18.4 0.0 13.1 15.8 35.9 25.5 41.1 24.5 18.3 59.9 12.6 44.5 21.5 17.3 MTARC1 "FLJ22390, MARC1, MOSC1" ENSG00000186205 "Mitochondrial amidoxime reducing component 1" Q5VT66 1 220786913-220819659 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 192.3;breast: 86.2;liver: 84.5" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 109.8;Extravillous trophoblasts: 47.9;Syncytiotrophoblasts: 75.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 30.2;classical monocyte: 33.6;eosinophil: 12.3;neutrophil: 42.8" "Group enriched" "Detected in many" 31 "granulocytes: 42.8;monocytes: 33.6" "Cell line enhanced" "Detected in many" "BEWO: 126.5;HeLa: 56.2;Hep G2: 67.6;NTERA-2: 57.8;OE19: 49.4" HPA028702 Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA028702: AB_10601135" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (2.16e-2)" "unprognostic (5.04e-2)" "unprognostic (2.90e-1)" "unprognostic (2.31e-1)" "unprognostic (3.71e-3)" "unprognostic (1.39e-1)" "unprognostic (7.51e-2)" "unprognostic (7.71e-3)" "unprognostic (3.71e-1)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.85e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" 192.3 7.4 9.4 6.8 10.5 17.9 86.2 9.8 13.2 7.9 7.9 18.9 7.6 2.8 14.0 7.6 6.2 4.1 8.4 10.0 11.7 10.2 84.5 9.3 2.8 10.1 11.8 5.5 9.6 5.4 7.0 16.0 9.6 36.2 17.3 5.7 27.2 13.5 11.0 3.6 9.7 4.0 9.1 10.2 9.3 1.4 14.3 1.6 53.5 9.2 2.1 8.8 5.0 8.5 15.0 7.8 5.9 0.2 1.3 0.3 126.5 1.4 1.2 0.8 1.5 45.4 1.0 0.1 5.3 1.6 0.1 0.1 28.3 2.9 2.1 0.2 25.7 0.1 56.2 67.6 2.7 0.3 0.5 4.5 1.3 0.2 0.0 0.2 1.1 0.1 4.3 0.3 1.1 14.7 0.1 31.9 57.8 49.4 23.8 0.1 0.0 0.3 7.1 17.4 16.4 36.1 8.1 11.4 0.2 16.4 38.5 34.7 0.4 0.1 12.6 0.1 0.1 0.2 0.1 0.1 0.2 0.0 1.1 30.2 33.6 12.3 0.1 2.5 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.0 42.8 0.0 1.3 0.3 0.0 9.2 9.4 10.5 9.8 13.2 10.0 11.7 10.1 11.8 9.6 9.1 14.3 8.5 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 47.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 MTCL1 "CCDC165, KIAA0802, SOGA2" ENSG00000168502 "Microtubule crosslinking factor 1" Q9Y4B5 18 8705661-8832778 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 90.1;intestine: 28.1;retina: 34.0" "Cell type enhanced" "Detected in many" "Early spermatids: 26.0;Excitatory neurons: 86.4;Granulosa cells: 28.9;Inhibitory neurons: 80.4;Oligodendrocyte precursor cells: 24.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "cerebellum: 90.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 32.0" HPA046245 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046245: AB_10962580" "unprognostic (2.64e-1)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.35e-1)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-1)" "unprognostic (4.41e-4)" "unprognostic (1.30e-2)" "unprognostic (7.19e-2)" "unprognostic (9.95e-2)" "unprognostic (2.51e-1)" "unprognostic (1.79e-2)" "prognostic unfavorable (5.19e-4)" "unprognostic (2.82e-1)" "unprognostic (3.67e-1)" "unprognostic (7.17e-3)" "unprognostic (1.08e-2)" 1.6 0.9 0.0 2.5 0.6 0.5 1.4 90.1 10.1 4.7 0.0 28.1 1.8 2.3 0.7 2.7 1.0 8.1 2.9 0.7 0.5 2.5 1.3 1.2 0.8 4.9 2.6 1.1 3.7 2.8 5.6 2.3 7.3 1.7 1.7 34.0 1.4 3.0 2.1 2.5 4.3 5.2 0.9 0.6 8.9 8.0 0.0 3.7 0.4 1.1 0.5 9.4 4.6 6.3 16.8 35.3 17.4 10.2 7.6 14.1 0.7 22.9 16.9 18.6 13.4 10.4 5.8 10.5 12.8 16.1 13.9 2.5 5.5 9.4 8.5 2.1 4.5 5.1 10.1 9.4 10.9 0.1 7.3 8.3 6.8 10.5 7.2 12.1 14.8 8.8 1.1 17.8 8.7 5.0 0.7 2.5 7.9 40.2 15.2 14.0 12.5 3.8 26.9 29.9 39.3 8.8 10.5 3.0 2.7 14.3 1.0 0.6 28.2 33.8 17.6 27.4 23.8 3.4 2.8 5.1 8.4 0.6 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 90.1 10.1 0.7 0.5 4.9 2.6 7.3 0.9 0.0 6.3 0.4 0.0 1.1 9.4 1.3 0.0 2.8 0.0 4.6 0.0 1.5 1.9 6.5 8.6 0.6 1.8 0.0 5.0 1.8 1.8 1.9 5.6 26.0 2.8 2.3 2.1 1.2 4.6 86.4 3.5 0.4 1.5 5.6 7.8 2.5 28.9 4.6 1.0 0.6 0.0 80.4 1.5 0.0 0.6 0.0 8.8 1.2 0.3 0.0 8.4 0.1 0.0 0.0 24.1 18.3 8.6 0.2 0.4 1.9 4.6 0.2 1.9 0.0 0.0 0.0 0.8 1.9 0.9 5.2 3.0 0.0 1.0 0.4 1.3 1.2 1.3 MTMR1 ENSG00000063601 "Myotubularin related protein 1" Q13613 X 150692971-150765108 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 79.3;Excitatory neurons: 61.2;Inhibitory neurons: 58.1;Oligodendrocyte precursor cells: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 104.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018502, HPA075953" Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA018502: AB_1854185, HPA075953: " "unprognostic (2.37e-2)" "unprognostic (1.64e-3)" "unprognostic (2.07e-1)" "unprognostic (1.05e-2)" "unprognostic (4.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (4.35e-2)" "unprognostic (3.16e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-2)" "unprognostic (1.67e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.19e-1)" "unprognostic (8.40e-2)" 6.7 7.2 11.3 11.1 13.0 11.9 12.5 11.7 13.0 9.3 7.1 10.2 9.0 7.9 7.1 20.6 9.7 7.2 12.2 17.3 10.8 8.3 9.0 9.5 21.8 7.5 10.0 8.5 10.0 17.9 9.2 14.2 7.6 10.9 9.4 22.1 12.4 10.9 22.9 21.4 10.4 7.3 9.2 14.3 10.7 8.0 11.9 31.3 10.0 16.0 25.5 12.6 13.5 8.7 32.3 20.3 21.5 17.7 4.9 5.7 28.8 28.1 36.0 28.0 39.4 19.8 24.9 70.2 40.1 22.9 27.1 28.4 43.9 40.8 43.2 28.4 26.3 4.4 31.6 8.5 14.5 20.7 14.6 15.6 27.7 30.8 0.4 26.8 17.1 22.9 13.8 17.5 20.3 27.7 30.6 5.3 9.9 35.9 30.3 16.0 34.1 31.2 22.0 36.4 31.9 19.9 10.7 23.7 8.8 17.0 30.3 11.8 21.7 18.3 14.6 2.3 42.1 22.2 24.6 104.8 3.7 13.3 14.4 0.0 0.5 5.0 2.1 0.9 1.5 1.7 2.3 1.9 1.4 1.9 2.0 2.8 1.5 3.9 0.9 5.0 3.2 1.2 11.3 13.0 11.7 13.0 17.3 10.8 7.5 10.0 7.6 9.2 11.9 8.7 3.7 16.0 6.5 79.3 11.4 11.2 11.0 8.0 6.8 0.0 7.8 5.5 8.2 2.8 7.5 5.5 0.0 10.1 19.3 4.6 0.0 5.9 0.0 10.0 3.7 3.6 9.6 6.5 61.2 6.6 7.3 4.5 7.7 9.2 1.3 4.8 2.9 8.0 4.6 0.0 58.1 5.5 8.2 9.4 8.8 1.7 5.6 4.8 3.6 30.0 6.2 0.0 8.2 54.8 22.6 10.6 8.6 5.3 7.9 11.0 3.8 3.1 8.4 0.0 6.6 6.7 3.9 2.5 3.0 10.3 16.8 10.4 8.8 5.9 5.9 12.5 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "salivary gland: 2621.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 443.2;Distal enterocytes: 158.4;Intestinal goblet cells: 210.1;Undifferentiated cells: 183.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "OE19: 113.9;PC-3: 120.0" "Not detected" "Not detected" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" NA NA 1300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB009396: AB_2282256, HPA008246: AB_1854203" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (2.76e-3)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.89e-2)" "unprognostic (7.80e-3)" "unprognostic (3.75e-1)" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (8.95e-2)" "unprognostic (2.57e-7)" "unprognostic (2.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" 0.1 0.7 0.2 2.0 0.1 0.0 1.3 0.0 0.4 229.4 0.0 58.0 0.1 0.3 0.0 101.0 1.1 221.3 0.1 0.0 0.0 0.1 2.4 7.5 0.0 0.1 0.0 0.1 9.8 0.0 0.4 0.0 0.0 0.6 17.1 0.0 2621.9 0.0 0.3 0.4 2.6 0.6 0.0 0.0 6.9 0.3 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.2 0.0 113.9 120.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 2.3 0.0 0.0 6.7 0.6 0.0 6.4 4.3 12.4 443.2 64.0 0.0 0.0 0.1 0.0 158.4 0.0 0.9 0.0 1.4 0.8 0.9 24.5 0.0 0.1 0.0 0.1 1.1 12.8 7.2 4.5 0.0 0.0 1.2 0.2 0.0 0.0 210.1 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 53.4 0.0 1.4 1.3 0.1 0.2 24.5 0.0 0.0 0.0 3.0 0.0 0.5 1.6 0.0 0.1 0.7 0.1 183.1 1.1 MUC7 "FLJ27047, MG2" ENSG00000171195 "Mucin 7, secreted" Q8TAX7 4 70430492-70482997 "Disease related genes, Predicted secreted proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 875 "salivary gland: 26019.1" "Cell type enriched" "Detected in some" 12 "Melanocytes: 12.4" "Group enriched" "Detected in some" 12 "head and neck cancer: 8.1;melanoma: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA006411 Enhanced "Secreted to digestive system" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 48: Smooth muscle cells - ECM organization" "HPA006411: AB_1854204" "unprognostic (5.49e-2)" "unprognostic (3.20e-1)" "unprognostic (1.06e-1)" 1.2 5.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.7 0.0 1.0 0.0 0.1 0.0 2.1 0.0 0.0 6.6 0.0 0.0 1.0 3.7 0.6 0.0 0.0 0.7 6.5 29.7 0.0 1.9 3.2 0.0 0.8 0.0 0.0 26019.1 0.0 2.6 3.6 1.5 0.0 0.0 1.0 1.1 1.5 0.2 0.0 1.3 0.1 0.4 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 12.4 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MVD MPD ENSG00000167508 "Mevalonate diphosphate decarboxylase" P53602 16 88651935-88663161 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041404, HPA048250" Uncertain Approved "Cell Junctions,Cytosol" NA NA 170000 "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Cell Junctions" "HPA041404: AB_2677457, HPA048250: AB_2680329" "unprognostic (1.67e-1)" "unprognostic (3.05e-1)" "unprognostic (2.42e-1)" "prognostic favorable (2.17e-4)" "unprognostic (1.89e-1)" "unprognostic (9.56e-2)" "unprognostic (9.26e-3)" "unprognostic (8.33e-2)" "unprognostic (6.68e-2)" "unprognostic (5.47e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-2)" "unprognostic (1.19e-3)" "unprognostic (4.12e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (5.00e-2)" 20.3 51.1 24.2 15.7 27.5 7.0 16.4 26.2 37.5 30.5 19.3 32.3 35.1 20.3 2.2 77.8 13.5 4.9 22.8 24.7 27.8 28.8 78.8 31.0 12.3 32.4 27.8 19.6 25.3 8.3 18.9 6.3 39.3 23.5 4.2 3.4 25.1 6.5 27.2 52.3 26.6 5.7 24.0 24.6 31.5 42.3 24.7 7.0 21.1 8.3 6.8 17.6 36.9 25.6 50.6 34.2 52.4 33.1 18.1 38.7 29.5 25.1 26.0 17.7 14.6 86.1 119.7 24.4 39.8 15.7 63.7 72.8 25.0 133.1 4.9 15.7 38.3 17.8 18.2 127.0 35.9 11.6 11.8 30.9 24.6 46.6 13.5 8.7 18.0 58.0 51.7 13.1 10.2 115.9 39.3 56.6 61.5 17.7 31.3 40.2 15.0 62.3 49.8 33.0 52.2 17.9 62.0 13.3 18.5 11.4 67.8 51.3 39.0 14.7 29.8 27.2 14.2 34.9 17.6 83.2 17.9 55.7 25.7 5.6 12.6 2.4 26.8 13.7 20.4 16.1 18.0 17.9 15.0 22.6 13.2 16.6 1.8 28.3 15.4 28.0 20.4 15.4 24.2 27.5 26.2 37.5 24.7 27.8 32.4 27.8 39.3 24.0 24.7 25.6 17.2 25.6 48.2 22.2 21.5 15.2 12.9 106.3 4.0 27.2 26.5 14.1 16.7 21.5 56.9 20.2 6.2 20.2 79.6 117.5 25.4 30.8 61.6 17.7 10.0 15.8 32.9 26.5 23.4 62.3 29.2 15.5 41.8 26.5 16.5 27.4 20.7 147.2 38.6 23.5 17.0 75.3 32.6 25.5 21.6 96.2 8.1 20.3 21.4 6.5 32.2 16.5 55.6 11.1 14.5 30.0 79.4 9.1 46.3 20.1 47.1 22.6 21.5 18.1 6.6 7.0 20.7 50.8 13.0 13.8 21.6 48.8 36.3 35.5 65.2 20.6 MVK "LRBP, MK" ENSG00000110921 "Mevalonate kinase" Q03426 12 109573255-109598125 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.1" "Cell type enhanced" "Detected in all" "Early spermatids: 60.5;Horizontal cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016961, HPA044110" Approved Supported Vesicles,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Cytosol" "HPA016961: AB_1854220, HPA044110: " "unprognostic (3.10e-1)" "unprognostic (2.27e-2)" "unprognostic (1.85e-1)" "unprognostic (4.43e-2)" "unprognostic (3.66e-2)" "unprognostic (2.08e-2)" "unprognostic (4.30e-2)" "unprognostic (8.98e-2)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (8.23e-2)" "unprognostic (1.30e-1)" "unprognostic (6.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (3.88e-1)" "unprognostic (3.28e-1)" 7.9 29.8 12.7 6.1 13.7 8.3 14.7 16.7 15.0 14.5 9.6 11.2 13.9 7.3 10.2 45.5 6.3 5.3 9.4 11.1 13.2 32.1 69.1 11.4 6.9 36.1 15.5 10.7 10.0 11.5 11.6 5.4 38.6 12.3 8.6 7.3 13.7 7.0 12.1 33.3 9.8 5.0 15.3 6.7 11.8 28.5 15.3 4.2 15.1 8.8 9.1 9.5 20.1 24.4 30.1 25.0 29.9 13.7 11.2 27.3 14.4 9.5 21.7 30.0 32.8 31.4 33.8 17.7 7.8 11.7 48.1 36.0 31.6 50.0 13.2 19.0 18.1 9.9 15.7 53.7 31.5 11.1 13.0 27.2 42.1 48.8 13.6 12.6 20.9 19.0 18.7 17.4 13.6 34.5 12.0 34.6 22.6 14.9 32.3 10.5 22.1 37.0 67.4 40.9 25.1 18.7 19.8 58.7 14.0 11.0 59.7 21.1 14.1 13.2 14.5 12.0 12.8 13.3 20.6 28.2 16.1 29.2 16.6 1.0 6.9 4.0 12.6 6.5 11.3 9.4 7.4 12.4 8.6 14.1 10.9 8.3 1.6 11.0 4.6 7.0 7.6 6.4 12.7 13.7 16.7 15.0 11.1 13.2 36.1 15.5 38.6 15.3 15.3 24.4 6.1 12.8 12.4 6.8 8.3 4.7 5.2 39.7 4.6 12.4 13.1 11.0 5.7 11.5 25.8 14.7 18.8 33.0 7.3 10.4 21.5 15.6 60.5 5.8 2.3 7.1 9.0 4.8 5.1 18.1 15.3 6.8 9.7 5.1 1.3 14.7 6.4 32.7 15.6 62.2 5.2 7.8 10.2 3.4 2.2 42.5 8.1 4.8 7.2 3.7 10.3 10.6 10.3 4.0 15.3 13.2 3.2 7.2 4.1 5.5 16.4 52.4 13.5 12.2 6.6 4.0 8.2 33.9 16.8 12.0 8.5 47.9 6.1 44.8 11.1 4.6 MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 35.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.5;Collecting duct cells: 31.3;Exocrine glandular cells: 60.7;Fibroblasts: 56.0;Pancreatic endocrine cells: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 31.4;BJ hTERT+: 125.8;fHDF/TERT166: 59.8;HaCaT: 52.4;HSkMC: 24.7" "Low region specificity" "Detected in all" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" NA NA 2600000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" 12.0 10.3 0.2 9.4 0.3 0.0 13.5 0.0 0.4 35.0 0.0 7.5 4.4 6.8 2.7 9.4 3.0 8.0 11.1 0.2 0.1 5.3 4.5 5.3 1.6 0.3 0.3 2.9 16.1 1.7 0.9 5.8 0.2 7.3 10.4 0.0 6.1 10.4 1.5 29.6 4.6 15.9 0.5 3.6 10.3 0.1 1.2 5.7 9.8 5.1 3.7 19.9 7.2 0.1 0.0 0.0 0.8 0.0 0.2 31.4 0.0 19.6 125.8 0.2 0.2 0.0 0.6 0.0 1.7 59.8 0.2 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.7 5.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.1 0.3 0.3 0.2 0.5 1.2 0.1 10.3 0.0 0.0 0.0 0.0 38.5 7.1 10.5 20.5 0.0 2.0 4.6 1.9 0.0 3.7 31.3 0.0 0.1 0.3 0.9 0.0 2.2 0.0 1.0 8.4 4.6 0.0 0.0 0.7 60.7 0.7 56.0 0.0 1.6 0.0 0.0 10.8 0.1 0.3 0.0 1.1 0.0 0.0 0.3 16.9 0.0 0.0 0.3 17.8 4.7 0.6 0.0 0.0 0.5 0.2 42.8 0.0 1.5 0.1 0.2 0.1 0.1 1.0 0.2 0.0 7.3 9.8 0.0 0.0 5.5 21.7 0.3 1.1 0.9 0.4 2.0 MYBL2 "B-MYB, BMYB" ENSG00000101057 "MYB proto-oncogene like 2" P10244 20 43667019-43716495 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 91.8;lymphoid tissue: 55.5" "Cell type enhanced" "Detected in many" "B-cells: 33.0;dendritic cells: 32.6;Erythroid cells: 82.3;Extravillous trophoblasts: 32.3;Plasma cells: 139.6;Spermatogonia: 33.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 295.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 91.5" "Lineage enriched" "Detected in many" 34 "dendritic cells: 91.5" "Cell line enhanced" "Detected in many" "MCF7: 763.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017114, HPA030530, HPA055416" Uncertain Supported Nucleoplasm,Cytosol Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB017114: , HPA030530: AB_2673515, HPA055416: AB_2682811" "unprognostic (9.75e-3)" "unprognostic (1.29e-2)" "unprognostic (3.20e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (2.35e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.66e-3)" "unprognostic (9.23e-3)" "unprognostic (1.78e-1)" "unprognostic (2.38e-3)" "unprognostic (1.32e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-1)" "unprognostic (2.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" 1.6 0.6 0.1 24.2 0.1 91.8 1.6 0.1 0.2 1.1 0.2 8.6 7.0 1.4 0.1 10.1 0.4 1.0 0.4 0.1 0.1 0.6 1.1 1.8 55.5 0.1 0.1 0.3 11.2 0.1 0.2 5.7 0.1 0.5 6.9 0.0 1.6 0.2 0.1 4.2 7.8 2.1 0.1 27.8 6.1 15.6 0.4 33.3 0.5 0.0 53.5 3.5 2.5 0.1 195.8 121.8 105.4 109.6 1.0 3.5 136.2 87.0 29.0 265.6 194.6 600.2 118.8 393.6 49.2 37.8 55.8 116.1 192.1 59.6 98.8 74.2 124.1 183.2 118.7 164.2 0.2 168.6 121.7 2.4 5.1 101.6 22.9 5.9 72.2 189.6 188.1 470.3 23.8 763.7 346.0 236.3 121.8 155.4 105.4 237.3 216.3 222.1 49.6 39.7 96.7 140.6 255.6 253.3 26.1 110.4 167.2 183.1 34.0 16.3 264.3 118.3 151.5 162.1 363.8 606.5 34.2 142.3 103.9 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.2 0.0 91.5 1.3 0.8 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.2 0.0 0.0 0.0 33.0 4.2 0.8 0.8 0.0 0.0 2.5 3.4 2.0 1.5 0.1 0.0 0.0 14.4 32.6 3.4 0.0 0.4 5.9 0.9 1.3 1.8 0.0 82.3 0.4 0.9 32.3 4.8 10.2 2.9 0.0 18.9 0.7 1.4 13.5 0.0 0.3 5.1 0.0 2.4 2.6 14.1 0.0 3.2 1.8 0.0 0.0 0.0 1.0 0.0 0.5 0.7 1.1 0.0 139.6 0.3 0.5 0.0 0.0 0.0 0.0 0.1 3.9 7.0 33.6 8.2 2.4 3.7 3.0 1.2 8.6 2.4 MYBPC1 ssMyBP-C ENSG00000196091 "Myosin binding protein C1" Q00872 12 101568353-101686028 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 87 "skeletal muscle: 11290.5;tongue: 5207.7" "Cell type enhanced" "Detected in some" "Astrocytes: 34.6;Breast glandular cells: 102.4;Breast myoepithelial cells: 81.4;Cardiomyocytes: 64.7;Skeletal myocytes: 184.6" "Cancer enhanced" "Detected in many" "prostate cancer: 33.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "HAP1: 6.8" "Group enriched" "Detected in many" 9 "cerebellum: 39.6;olfactory bulb: 10.6" "Region enhanced" "Detected in many" "thalamus: 6.9" "HPA021004, HPA027614" Enhanced NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 37: Myocytes - Muscle contraction" "HPA021004: AB_1854232, HPA027614: AB_10602711" "prognostic favorable (4.76e-5)" "unprognostic (7.72e-2)" "unprognostic (1.09e-1)" "unprognostic (1.81e-2)" "unprognostic (3.33e-2)" "unprognostic (4.63e-2)" "unprognostic (8.67e-2)" "unprognostic (2.93e-1)" "unprognostic (9.98e-3)" "unprognostic (2.56e-1)" "unprognostic (2.55e-1)" "unprognostic (1.19e-2)" "unprognostic (4.10e-2)" "unprognostic (7.96e-2)" "unprognostic (6.13e-2)" "unprognostic (5.55e-3)" 1.5 0.3 55.5 0.1 66.5 0.0 63.7 60.4 71.6 1.9 36.3 4.5 0.1 0.2 1.1 94.7 0.8 0.3 1.8 50.1 59.5 0.3 0.7 0.7 0.0 52.3 64.5 0.5 1.1 0.0 0.3 0.0 55.0 83.5 0.8 0.0 48.4 0.3 11290.5 6.1 7.4 0.0 49.4 0.4 1.3 3.4 68.4 2.6 1.2 5207.7 4.0 0.3 0.7 49.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 66.5 60.4 71.6 50.1 59.5 52.3 64.5 55.0 49.4 68.4 49.9 1.3 0.0 0.0 34.6 0.3 0.0 2.2 0.0 0.0 0.0 102.4 81.4 64.7 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.0 16.5 0.1 0.1 1.2 0.0 0.0 5.3 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.2 0.0 0.8 0.3 23.7 0.6 1.2 1.8 1.0 0.0 0.0 0.0 0.5 0.5 0.1 1.6 0.4 0.0 16.3 0.3 0.1 0.0 0.0 0.0 184.6 2.7 1.4 1.4 0.0 0.0 0.0 0.7 0.0 0.3 2.9 MYCN "bHLHe37, MYCNOT, N-myc, NMYC" ENSG00000134323 "MYCN proto-oncogene, bHLH transcription factor" P04198 2 15940550-15947007 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 9.5" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 84.2;Granulosa cells: 26.4" "Cancer enriched" "Detected in many" 5 "testis cancer: 45.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 44.1;BEWO: 239.1;HMC-1: 57.3;NTERA-2: 91.3;RH-30: 63.3;SuSa: 40.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057420 Approved Nucleoplasm,Nucleoli NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "HPA057420: AB_2683434" "unprognostic (8.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.07e-2)" "unprognostic (4.11e-1)" "unprognostic (2.46e-2)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.09e-2)" "unprognostic (2.09e-1)" "unprognostic (1.12e-3)" "unprognostic (8.89e-2)" "unprognostic (2.47e-1)" "unprognostic (4.90e-2)" "unprognostic (1.23e-1)" 0.4 0.8 3.5 0.6 3.5 0.9 0.4 3.1 3.9 1.5 0.8 0.6 1.6 0.9 0.1 0.7 0.5 0.3 1.2 3.4 3.0 3.3 0.8 0.7 1.6 4.4 3.9 5.1 0.2 0.1 0.3 9.5 3.7 0.1 0.5 1.0 4.7 0.2 0.4 1.4 0.9 0.3 3.3 0.3 4.6 3.6 3.5 2.9 2.9 0.7 1.2 0.5 0.4 5.9 0.0 0.0 44.1 0.0 0.0 0.0 239.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 4.2 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 16.8 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.8 0.4 0.2 91.3 2.1 0.0 0.0 63.3 12.8 0.0 3.1 1.0 16.0 0.0 0.1 0.0 40.9 0.1 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.5 3.1 3.9 3.4 3.0 4.4 3.9 3.7 3.3 3.5 5.9 0.8 0.0 0.0 0.7 0.0 0.5 0.1 0.0 0.0 2.6 0.1 0.9 0.7 0.0 0.0 0.0 0.0 5.6 0.0 0.2 0.0 0.0 1.2 0.5 0.1 2.7 0.0 4.2 2.0 0.0 84.2 1.0 2.6 0.8 0.0 26.4 0.0 0.6 2.4 0.0 4.2 0.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.1 1.0 0.0 10.1 7.5 0.3 1.1 0.4 0.0 0.0 0.4 3.2 0.0 0.2 0.0 4.2 0.7 1.3 3.7 0.3 0.0 11.5 0.0 9.4 0.3 0.0 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 MYH14 "DFNA4, FLJ13881, KIAA2034, MHC16, MYH17" ENSG00000105357 "Myosin heavy chain 14" Q7Z406 19 50188186-50310542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 191.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 487.2;Paneth cells: 306.4;Proximal enterocytes: 376.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 48.6;CAPAN-2: 59.4;HaCaT: 119.0;MCF7: 59.0;OE19: 61.7;RT4: 147.8;SK-BR-3: 51.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062391, HPA067889, HPA070260" Enhanced Approved Nucleoplasm NA NA 9600000 "Cluster 80: Striated muscle - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA062391: AB_2684748, HPA067889: AB_2685917, HPA070260: AB_2686243" "unprognostic (2.52e-1)" "unprognostic (5.81e-2)" "unprognostic (9.63e-2)" "unprognostic (3.73e-3)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.71e-1)" "unprognostic (3.48e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "prognostic favorable (3.97e-8)" "prognostic favorable (7.83e-4)" "unprognostic (8.50e-2)" "unprognostic (3.12e-1)" "unprognostic (2.77e-1)" 12.6 1.0 24.1 7.0 35.0 0.0 8.8 38.2 23.3 13.3 22.0 64.5 83.8 1.5 0.2 63.7 15.4 3.6 41.3 20.0 30.9 10.2 25.4 24.4 0.1 38.7 35.6 0.4 17.3 16.7 18.5 0.4 35.7 8.8 19.5 5.1 44.0 5.7 191.3 87.7 76.7 1.3 29.5 0.1 45.5 2.6 34.4 1.5 33.2 35.1 6.1 11.0 31.8 37.4 48.6 5.0 0.0 25.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 33.1 59.4 0.2 30.1 0.0 3.7 119.0 0.1 0.0 0.0 0.1 8.7 0.0 0.0 25.7 0.0 0.0 17.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 59.0 0.0 0.3 0.8 61.7 0.7 0.1 29.4 0.7 0.0 147.8 0.1 0.2 2.9 51.8 0.0 0.2 9.7 1.9 0.0 0.1 11.7 0.2 0.1 0.9 11.2 0.3 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 35.0 38.2 23.3 20.0 30.9 38.7 35.6 35.7 29.5 34.4 37.4 0.1 80.1 36.5 23.5 2.8 3.3 18.7 29.3 0.0 3.7 17.9 9.3 21.8 44.3 50.9 57.0 2.1 0.1 0.3 487.2 0.0 53.2 0.9 58.1 6.0 1.2 51.6 0.0 10.9 27.2 0.1 1.1 85.1 70.7 14.7 0.0 2.9 45.8 0.1 16.8 21.7 109.4 22.4 0.8 1.6 0.8 0.3 1.3 5.4 2.8 0.0 19.7 0.0 23.6 27.5 67.5 306.4 0.0 0.3 30.8 376.1 7.6 80.6 11.5 0.0 17.7 3.5 0.5 4.6 30.8 21.0 0.0 2.0 0.0 122.8 86.2 MYL9 "LC20, MLC2, MRLC1, MYRL2" ENSG00000101335 "Myosin light chain 9" P24844 20 36541497-36551447 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 8015.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 860.2;Cardiomyocytes: 1856.1;Peritubular cells: 1891.9;Sertoli cells: 2143.1;Smooth muscle cells: 2525.7;Theca cells: 881.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 783.3;BJ: 1047.3;fHDF/TERT166: 844.3;hTERT-RPE1: 645.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 76.1" "HPA039262, HPA045244, HPA059197" Supported NA NA 34000000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (1.15e-1)" "unprognostic (5.05e-2)" "unprognostic (2.67e-3)" "unprognostic (5.38e-2)" "unprognostic (7.17e-2)" "unprognostic (5.06e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (9.06e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (7.92e-7)" "unprognostic (1.90e-2)" "unprognostic (8.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.92e-2)" 944.6 948.6 61.6 347.0 76.7 5.2 649.5 63.3 132.2 1083.0 104.6 8015.9 270.5 2897.3 238.2 999.8 1643.3 364.3 2294.5 61.4 63.1 352.2 116.6 617.9 56.4 66.3 66.3 717.2 82.0 45.4 91.2 160.3 66.1 2347.4 345.8 22.8 200.7 2248.7 164.3 289.2 1287.7 2107.8 62.0 274.3 1946.4 260.7 66.5 27.4 431.7 111.4 23.2 4176.1 943.6 63.3 79.4 1.3 60.3 1.2 783.3 298.6 264.5 1047.3 450.9 541.3 349.9 612.3 9.1 0.2 535.6 844.3 120.6 29.4 0.2 2.4 125.7 0.9 0.2 16.7 114.4 57.3 500.4 0.4 17.7 420.8 54.4 359.9 1.6 645.9 19.2 0.0 2.4 28.0 461.7 0.2 0.3 7.8 24.0 16.1 5.6 0.4 0.0 5.8 4.6 5.8 0.6 4.1 11.1 26.6 0.6 257.5 232.9 15.6 137.0 510.9 220.1 75.5 1.0 0.8 4.0 2.3 194.3 0.8 0.6 0.0 0.1 2.2 0.0 0.0 0.0 0.9 0.0 0.1 0.3 0.2 0.0 0.0 1.9 0.2 0.0 0.4 0.0 7.2 61.6 76.7 63.3 132.2 61.4 63.1 66.3 66.3 66.1 62.0 66.5 63.3 325.3 394.2 52.3 0.0 6.6 60.7 320.2 167.1 21.6 1.4 36.8 860.2 1856.1 24.3 50.8 90.1 0.0 37.0 6.3 0.1 27.4 310.3 9.3 13.1 419.9 179.7 0.0 5.7 0.2 116.0 78.3 410.4 10.2 9.3 15.2 234.3 169.9 2.7 32.0 1.7 0.1 1.2 14.2 5.0 76.6 55.4 331.8 111.7 72.9 30.9 19.4 230.4 6.2 0.0 0.5 47.9 2.5 1891.9 6.4 156.9 105.5 42.1 31.8 6.1 2143.1 65.9 2525.7 16.3 9.5 6.5 53.4 26.8 14.7 881.1 2.0 61.9 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1700.3;smooth muscle: 2137.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 728.5;Hepatocytes: 208.7;Peritubular cells: 690.5;Sertoli cells: 276.1;Smooth muscle cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 200.0;BJ hTERT+: 298.2;fHDF/TERT166: 260.2;hTERT-RPE1: 202.7;RPTEC TERT1: 291.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 143.6 57.4 37.6 188.7 64.8 3.3 163.4 72.1 42.4 281.3 14.1 551.5 110.9 669.2 232.9 420.6 289.8 250.4 33.6 33.6 46.7 64.4 67.2 85.2 33.6 104.6 64.8 95.9 15.3 11.6 2.6 70.2 99.3 907.6 299.1 13.6 140.1 1700.3 10.0 20.1 125.1 2137.7 55.6 89.5 122.7 50.5 52.2 8.0 22.2 14.9 19.1 505.7 84.8 112.1 14.4 38.4 10.8 7.8 10.8 1.9 4.7 200.0 298.2 137.3 92.1 8.1 7.4 0.6 42.5 260.2 67.0 4.8 5.2 1.8 149.0 0.2 0.7 102.4 0.9 28.9 56.1 0.6 9.8 36.9 3.5 24.4 34.4 202.7 8.9 1.3 1.2 0.5 90.9 1.7 0.2 2.5 12.0 0.5 5.1 13.5 6.8 36.7 291.9 8.5 1.4 6.4 21.8 1.9 3.1 25.0 1.0 0.3 33.4 39.5 13.9 10.3 30.7 3.4 4.2 0.3 104.0 1.0 9.6 7.4 1.6 0.4 0.1 0.2 0.0 0.2 0.0 0.0 3.5 0.1 0.2 0.1 5.0 0.0 0.0 3.3 0.2 20.9 37.6 64.8 72.1 42.4 33.6 46.7 104.6 64.8 99.3 55.6 52.2 112.1 45.9 16.0 38.3 43.4 2.5 20.5 27.2 24.8 1.2 2.9 19.9 728.5 25.2 37.1 5.7 27.6 125.1 0.8 3.5 88.1 3.9 6.0 40.7 45.9 46.6 56.9 11.4 3.2 25.2 3.9 0.8 40.1 3.1 54.4 2.5 3.2 45.3 208.7 4.9 3.3 3.4 3.9 8.2 7.9 37.0 33.8 104.7 20.8 19.6 8.4 1.2 4.7 0.0 5.5 37.0 4.0 18.7 690.5 3.3 8.6 14.2 17.2 17.6 19.9 276.1 5.6 448.7 4.7 4.6 1.3 20.2 2.5 3.2 4.5 4.2 3.7 MYO15B MYO15BP ENSG00000266714 "Myosin XVB" Q96JP2 17 75588058-75626849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 179.2" "Group enriched" "Detected in many" 4 "Distal enterocytes: 275.4;Paneth cells: 294.2;Proximal enterocytes: 127.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A549: 46.4;HEL: 17.7;HMC-1: 24.9;THP-1: 37.7" "Not detected" "Not detected" "HPA022857, HPA023105" Approved Cytosol No No "Cluster 34: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA022857: AB_1848813, HPA023105: AB_1859526" "prognostic favorable (9.34e-4)" "unprognostic (7.55e-2)" "unprognostic (6.99e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (5.59e-4)" "unprognostic (7.29e-3)" "unprognostic (1.48e-1)" "unprognostic (4.97e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-3)" "unprognostic (1.04e-2)" "unprognostic (1.49e-1)" "unprognostic (6.39e-2)" "unprognostic (1.68e-1)" "unprognostic (3.35e-1)" "prognostic favorable (6.90e-5)" 40.0 17.3 34.7 17.3 39.2 57.0 38.1 33.7 45.1 74.7 29.6 53.6 179.2 46.1 7.5 18.6 65.6 25.8 44.4 32.0 34.0 76.0 29.8 55.1 19.2 39.9 36.8 87.1 20.5 4.7 28.9 15.0 40.1 56.5 21.5 9.9 23.6 14.0 13.2 15.9 149.0 9.8 35.5 108.2 25.7 20.9 36.7 17.7 65.8 8.0 7.2 29.0 44.0 46.1 0.6 46.4 0.3 1.2 0.3 0.1 0.7 0.0 0.0 0.0 0.0 5.8 13.6 0.1 1.5 0.0 0.6 0.5 0.0 0.0 0.0 0.6 2.8 17.7 9.5 11.6 1.3 0.0 24.9 0.8 0.8 0.0 0.1 0.8 0.3 7.3 1.2 5.1 0.0 5.0 0.4 7.8 0.7 12.3 11.2 12.7 0.3 2.1 0.3 1.0 1.3 3.2 0.3 0.5 1.5 1.4 3.5 37.7 0.1 0.3 1.2 0.2 0.0 1.7 0.2 0.2 0.7 8.9 0.6 1.3 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.3 0.0 0.4 0.2 0.0 0.1 34.7 39.2 33.7 45.1 32.0 34.0 39.9 36.8 40.1 35.5 36.7 46.1 13.7 0.0 3.3 44.7 8.4 2.4 2.4 2.0 8.0 4.5 4.0 2.7 7.5 11.5 2.4 9.2 16.7 0.1 11.9 275.4 1.9 1.6 0.7 11.6 8.9 14.6 31.7 9.2 1.1 1.5 0.1 7.1 52.0 8.1 14.0 13.6 21.0 2.1 5.5 1.7 1.4 40.3 12.2 10.0 12.6 2.7 5.6 17.5 3.6 42.2 6.9 4.9 12.3 32.6 46.6 8.8 294.2 4.9 1.4 1.9 127.5 14.4 8.0 13.5 6.6 7.1 8.4 3.3 6.8 2.2 3.0 0.1 6.2 4.7 20.1 1.8 MYO18B BK125H2.1 ENSG00000133454 "Myosin XVIIIB" Q8IUG5 22 25742144-26031045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 120.8;skeletal muscle: 262.7;tongue: 55.6" "Group enriched" "Detected in some" 21 "Cardiomyocytes: 95.5;Early spermatids: 61.4;Late spermatids: 37.3;Skeletal myocytes: 32.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.8" "Region enhanced" "Detected in single" "thalamus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 10.6;REH: 15.0;RH-30: 30.5;U-2 OS: 13.2;U-266/70: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA000953 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Centrosome" "HPA000953: AB_1079440" "unprognostic (3.28e-2)" "unprognostic (1.79e-1)" "unprognostic (1.86e-2)" "unprognostic (1.23e-1)" "unprognostic (1.66e-2)" "unprognostic (1.01e-2)" "unprognostic (5.93e-4)" "unprognostic (2.46e-1)" "unprognostic (1.22e-1)" "unprognostic (7.14e-2)" "unprognostic (4.36e-3)" "unprognostic (2.96e-3)" "unprognostic (3.93e-7)" "unprognostic (1.14e-1)" "unprognostic (3.12e-1)" "unprognostic (5.06e-2)" "unprognostic (1.65e-1)" 0.2 0.1 0.3 0.1 0.1 1.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 120.8 0.1 0.3 0.1 0.0 0.1 0.1 0.3 0.8 0.0 0.1 0.0 0.2 0.0 0.3 1.0 0.0 0.0 2.7 0.0 262.7 0.5 0.0 0.0 0.2 0.0 1.5 10.2 2.3 1.9 0.1 55.6 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 5.3 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.0 4.0 0.0 0.4 1.6 0.0 0.0 0.0 15.0 30.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 13.2 0.0 0.0 9.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.1 0.3 0.3 0.8 0.3 0.2 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.4 0.0 0.2 1.2 0.0 0.0 1.8 0.0 0.0 1.7 2.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 37.3 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 14.1;kidney: 5.3;parathyroid gland: 8.8;retina: 5.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 85.5;Early spermatids: 34.2;Inhibitory neurons: 18.3;Late spermatids: 29.6;Rod photoreceptor cells: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HDLM-2: 11.2;HEL: 8.8;RT4: 11.7" "Region enriched" "Detected in some" 5 "basal ganglia: 5.2" "Not detected" "Not detected" HPA045483 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA045483: AB_2679344" "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (7.15e-3)" "unprognostic (5.07e-2)" "unprognostic (2.61e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-1)" "unprognostic (7.99e-3)" "unprognostic (2.59e-1)" "unprognostic (4.25e-5)" "unprognostic (2.34e-1)" "unprognostic (8.12e-3)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 14.1 0.4 0.6 0.1 0.0 0.0 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 8.8 0.3 0.0 0.0 0.0 0.0 5.8 0.1 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.4 1.3 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 11.2 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 1.1 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.3 0.6 0.5 0.3 0.0 3.1 0.2 0.3 0.7 0.0 0.5 3.7 85.5 0.0 0.6 0.1 13.7 0.3 34.2 5.3 0.4 0.3 1.8 0.0 1.8 0.0 0.0 0.8 0.0 1.7 0.0 0.1 0.0 0.2 0.0 0.0 18.3 0.6 0.0 0.3 1.1 29.6 0.3 0.2 0.0 1.9 0.0 3.0 0.0 5.5 2.9 0.1 0.0 0.4 0.0 0.2 0.0 0.2 0.2 51.0 0.0 1.7 0.5 1.5 0.8 0.3 0.4 0.1 0.3 0.3 0.0 0.1 MYO7B ENSG00000169994 "Myosin VIIB" Q6PIF6 2 127535802-127637729 "Predicted intracellular proteins" Differentiation "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 113.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 127.7;Intestinal goblet cells: 48.3;Paneth cells: 74.9;Proximal enterocytes: 151.4;Undifferentiated cells: 45.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7;naive B-cell: 5.9" "Group enriched" "Detected in many" 22 "B-cells: 5.9;dendritic cells: 2.6;monocytes: 5.7" "Cell line enriched" "Detected in some" 10 "MOLT-4: 286.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039131 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA039131: AB_10672771" "unprognostic (4.10e-3)" "unprognostic (3.81e-2)" "unprognostic (3.80e-2)" "unprognostic (2.23e-4)" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (2.07e-1)" "unprognostic (8.51e-2)" "unprognostic (3.76e-1)" "unprognostic (3.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.80e-2)" "unprognostic (8.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" 0.1 0.0 0.2 4.9 0.2 6.5 0.1 0.2 0.3 0.0 0.0 35.9 113.2 0.0 6.7 0.3 0.4 13.0 0.2 0.7 1.8 8.5 0.3 1.0 4.0 0.5 1.1 0.0 0.2 0.0 0.0 1.7 1.1 0.1 25.3 0.0 0.1 0.2 0.8 0.3 84.4 1.2 0.5 11.3 0.4 1.4 0.3 9.0 0.2 0.0 1.6 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 14.5 5.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.2 0.0 28.1 0.0 0.0 0.2 0.0 286.1 0.8 0.0 0.5 1.7 0.5 1.9 0.3 0.5 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.1 0.5 0.1 0.6 8.6 0.4 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.7 0.1 0.0 2.2 0.0 0.8 0.0 0.0 2.6 5.9 0.0 0.2 0.1 0.0 1.4 0.7 0.0 2.4 0.2 0.2 0.2 0.3 0.7 1.8 0.5 1.1 1.1 0.5 0.3 0.8 2.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 12.8 0.0 5.5 0.0 0.1 1.5 127.7 1.9 0.2 0.1 0.0 0.0 1.0 25.8 0.0 0.2 0.2 2.0 0.1 1.5 0.0 0.0 0.1 2.9 0.2 0.1 0.0 0.4 48.3 0.0 0.0 0.3 0.4 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.5 0.1 1.6 74.9 0.0 0.0 0.0 151.4 9.9 0.0 0.0 0.0 2.8 0.1 0.6 1.1 0.0 0.1 0.3 0.6 0.0 45.7 0.1 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.8;lymphoid tissue: 272.2" "Cell type enriched" "Detected in many" 6 "Plasma cells: 4000.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 160.4;plasmacytoid DC: 569.3" "Group enriched" "Detected in many" 116 "B-cells: 160.4;dendritic cells: 569.3" "Group enriched" "Detected in some" 5 "Karpas-707: 581.5;RPMI-8226: 2193.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 350000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" 4.4 9.1 0.0 87.4 0.1 33.0 21.0 0.0 0.7 18.3 0.2 70.1 89.8 1.8 0.4 10.1 5.7 14.3 2.3 0.0 0.0 5.9 5.8 15.9 123.2 0.1 0.0 4.9 1.3 0.0 0.7 0.0 0.1 5.1 39.9 0.0 56.7 4.9 0.1 0.4 47.8 2.1 0.4 272.2 66.6 2.4 0.1 147.3 9.1 0.0 117.8 58.7 3.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 256.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 144.6 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 128.5 0.5 581.5 0.0 0.0 227.8 2.2 0.0 0.0 0.0 90.1 0.3 2193.9 0.0 0.0 0.3 0.8 0.0 11.4 0.0 0.0 3.1 0.1 0.6 0.0 1.8 0.1 0.0 262.0 16.7 223.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.1 3.0 160.4 0.6 1.1 0.5 75.6 0.1 0.2 3.1 2.7 0.0 569.3 0.2 26.1 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.4 6.4 10.1 0.0 665.7 2.5 1.3 0.1 0.0 0.0 3.7 3.2 1.1 4.3 2.0 0.0 0.0 0.1 235.0 0.9 0.0 0.1 0.1 1.8 0.4 2.0 1.2 49.3 0.0 0.0 0.1 2.0 6.1 0.4 2.5 0.1 11.4 14.0 0.1 0.0 0.0 1.1 0.0 7.1 3.4 1.1 0.0 4.7 540.7 0.0 1.0 0.0 4.1 0.0 0.0 0.1 0.4 0.0 4000.1 3.0 1.2 1.9 1.2 0.0 0.0 1.7 2.1 0.1 0.1 0.4 2.4 2.2 100.7 0.5 9.7 0.4 N4BP3 LZTS4 ENSG00000145911 "NEDD4 binding protein 3" O15049 5 178113532-178126081 "Predicted intracellular proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 35.7;Extravillous trophoblasts: 130.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 1.7;naive B-cell: 1.6;naive CD8 T-cell: 1.2;plasmacytoid DC: 2.1" "Group enriched" "Detected in many" 16 "B-cells: 1.7;dendritic cells: 2.1;T-cells: 1.2" "Cell line enhanced" "Detected in many" "BEWO: 14.9;MCF7: 21.2;RH-30: 20.3;SK-BR-3: 72.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030972, HPA030973, HPA061387" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm Centrosome "HPA030972: AB_2673680, HPA030973: AB_10603574, HPA061387: " "unprognostic (1.84e-1)" "unprognostic (1.70e-2)" "unprognostic (4.96e-3)" "unprognostic (6.64e-3)" "unprognostic (2.06e-1)" "unprognostic (3.18e-3)" "unprognostic (1.88e-6)" "unprognostic (1.45e-1)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (3.28e-3)" "unprognostic (9.55e-2)" "prognostic favorable (2.38e-4)" "unprognostic (2.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" 1.9 0.8 1.6 1.0 1.0 2.9 2.5 3.0 3.7 2.6 0.6 1.4 0.5 0.8 0.3 15.7 1.0 0.7 2.3 1.0 2.1 3.1 0.1 3.9 1.8 2.6 1.8 0.5 0.7 4.1 2.2 8.3 2.7 1.0 0.4 4.7 6.8 0.8 4.4 7.8 1.8 0.5 0.2 1.8 2.2 0.9 4.1 0.9 1.4 3.0 2.9 1.4 4.0 2.1 0.1 0.1 2.3 1.7 0.2 0.0 14.9 0.0 0.0 0.0 0.0 3.3 1.1 1.4 2.0 0.0 0.1 4.7 0.4 0.1 0.0 2.5 0.8 4.1 1.8 0.1 0.1 0.2 0.0 0.3 0.5 0.0 0.1 0.0 12.0 1.3 2.6 0.9 0.0 21.2 0.2 0.3 11.2 3.6 0.1 11.6 20.3 5.4 1.2 2.4 1.7 0.8 0.6 72.2 4.9 2.8 2.8 0.1 2.4 0.0 1.7 0.0 0.0 3.2 2.3 13.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.1 1.7 0.1 0.1 0.0 1.6 0.4 1.2 0.0 0.1 0.0 2.1 0.0 0.2 1.6 1.0 3.0 3.7 1.0 2.1 2.6 1.8 2.7 0.2 4.1 2.1 7.8 3.2 0.6 0.0 12.7 9.4 13.1 6.7 4.0 35.7 7.3 3.6 1.7 2.8 3.4 1.8 12.5 3.0 10.4 9.4 13.7 3.4 0.4 1.9 1.1 15.7 4.2 0.0 2.9 0.8 130.4 1.6 6.6 5.8 4.5 0.5 0.4 0.2 2.3 1.7 4.9 3.7 6.1 0.0 1.7 0.8 0.6 1.0 12.4 3.7 1.1 2.0 0.0 0.5 0.2 7.3 8.7 1.9 6.1 10.3 0.1 0.8 0.3 9.2 0.0 2.5 0.7 0.2 8.1 14.1 6.8 23.1 3.0 0.7 3.5 12.1 NAB1 ENSG00000138386 "NGFI-A binding protein 1" Q13506 2 190646746-190692766 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 102.0;Suprabasal keratinocytes: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002738 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "HPA002738: AB_1079447" "unprognostic (1.44e-1)" "unprognostic (2.65e-2)" "unprognostic (6.02e-3)" "unprognostic (4.04e-3)" "unprognostic (9.05e-2)" "unprognostic (9.45e-2)" "unprognostic (7.12e-3)" "unprognostic (6.41e-2)" "unprognostic (2.13e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.52e-1)" "unprognostic (7.23e-3)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (3.85e-2)" 29.3 20.3 19.4 23.5 16.7 18.6 34.8 50.4 23.5 28.1 7.4 22.8 15.8 32.3 50.1 36.3 27.5 28.0 28.5 18.7 9.7 19.9 37.8 22.8 26.8 13.4 13.2 26.0 17.9 23.5 21.1 26.4 14.9 18.5 25.6 41.4 20.7 20.9 8.0 66.7 17.1 25.2 14.9 19.8 37.9 26.0 13.8 21.2 37.9 17.2 26.3 31.2 24.2 25.9 35.5 25.8 65.0 22.6 24.5 42.7 111.0 35.5 55.7 26.4 29.8 62.8 38.4 39.6 40.6 28.3 48.9 88.4 37.4 45.9 51.8 126.1 31.0 46.7 96.3 30.2 15.8 19.8 22.4 24.6 70.4 55.9 17.1 37.4 41.5 23.9 46.3 33.2 40.6 17.4 28.7 20.0 22.8 38.4 35.2 35.0 46.7 15.9 19.3 34.5 57.9 46.9 41.8 13.9 37.3 82.8 11.4 30.6 29.0 54.5 43.0 31.0 21.6 25.7 30.3 29.5 57.3 17.6 43.7 0.0 1.3 0.6 1.3 1.1 1.9 0.7 1.3 1.7 0.9 0.4 1.4 1.5 2.9 2.6 3.7 0.8 3.3 0.8 19.4 16.7 50.4 23.5 18.7 9.7 13.4 13.2 14.9 14.9 13.8 25.9 24.1 6.4 21.2 14.0 5.9 102.0 23.1 24.6 31.3 26.1 19.7 19.7 18.2 11.5 29.8 12.9 12.5 4.3 9.2 11.4 3.9 10.3 1.4 17.5 10.8 30.1 14.4 12.0 37.2 8.0 11.1 25.2 21.4 23.4 20.3 14.2 44.6 25.7 6.7 6.7 21.2 17.5 14.2 17.3 77.4 3.2 13.4 20.7 39.2 24.4 10.6 12.4 11.3 29.1 28.3 10.2 26.3 14.7 14.9 30.5 4.8 5.1 22.3 15.5 46.0 24.6 39.2 1.7 27.3 55.7 138.9 1.2 16.7 7.3 16.0 29.9 NAGLU NAG ENSG00000108784 N-acetyl-alpha-glucosaminidase P54802 17 42536241-42544449 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Charcot-Marie-Tooth disease, Disease variant, Mucopolysaccharidosis, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038815 Supported "Intracellular and membrane" NA NA 270000000 "Cluster 37: B-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA038815: AB_10697398" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (6.48e-2)" "prognostic favorable (4.17e-4)" "prognostic unfavorable (6.59e-4)" "unprognostic (1.46e-1)" "unprognostic (1.75e-3)" "unprognostic (3.09e-2)" "unprognostic (2.20e-1)" "unprognostic (6.68e-2)" "prognostic favorable (6.90e-4)" "unprognostic (8.07e-2)" "prognostic favorable (2.58e-6)" "unprognostic (2.25e-1)" "unprognostic (8.74e-3)" "unprognostic (2.15e-2)" "unprognostic (1.62e-1)" 41.6 37.9 12.5 14.8 21.6 20.3 35.3 16.6 16.7 31.1 28.7 25.1 24.3 34.7 12.8 19.5 27.6 27.4 20.1 12.0 15.0 39.3 59.3 30.8 24.0 18.0 19.2 35.2 63.8 21.3 22.5 26.1 20.1 28.3 16.4 3.1 37.7 18.4 16.0 25.1 30.9 13.8 14.2 40.7 35.1 8.7 19.5 17.1 37.6 9.7 13.4 28.9 23.9 30.0 16.0 55.3 10.8 24.6 106.6 34.5 36.4 24.0 56.9 24.9 31.7 14.9 40.4 20.3 23.7 37.4 54.7 38.3 9.7 11.7 5.5 15.8 20.2 11.2 31.3 31.8 35.3 13.3 27.7 41.4 17.8 13.6 16.9 27.3 32.8 3.6 16.6 39.3 27.9 38.9 2.2 23.0 12.6 34.6 7.0 8.7 23.6 47.2 33.1 36.1 16.2 24.4 12.9 17.6 20.4 15.6 82.1 14.1 25.8 59.3 9.7 23.8 15.7 52.6 25.8 17.6 35.9 14.4 43.1 1.1 2.4 1.9 2.5 1.8 2.4 2.4 1.0 1.3 2.1 1.8 1.8 1.4 1.1 2.1 2.9 2.8 0.2 1.1 12.5 21.6 16.6 16.7 12.0 15.0 18.0 19.2 20.1 14.2 19.5 30.0 14.1 12.8 7.8 17.3 9.0 2.8 6.1 3.9 2.2 15.5 14.2 8.9 3.8 18.6 4.9 18.4 4.2 23.8 11.4 21.1 3.9 18.4 0.3 5.8 14.5 12.2 6.7 4.4 2.3 33.2 14.5 26.4 27.0 12.1 2.5 40.1 24.3 43.7 37.6 15.2 3.1 17.6 0.0 26.0 3.5 2.4 19.9 19.0 16.0 10.3 5.9 13.2 8.2 6.0 19.2 15.8 5.4 12.8 12.9 10.7 23.0 31.8 3.7 6.7 6.6 18.0 12.8 0.4 6.0 6.1 3.4 18.5 6.0 74.6 15.0 6.0 NALCN "bA430M15.1, CanIon, VGCNL1" ENSG00000102452 "Sodium leak channel, non-selective" Q8IZF0 13 101053776-101416508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.1" "Group enriched" "Detected in some" 10 "Astrocytes: 125.4;Excitatory neurons: 265.8;Inhibitory neurons: 277.4;Oligodendrocyte precursor cells: 324.7;Oligodendrocytes: 477.4" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.6" "Cell line enhanced" "Detected in many" "HaCaT: 14.2;HHSteC: 14.4;hTERT-RPE1: 11.0;TIME: 19.8;U-87 MG: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031889, HPA031890, HPA031958" Approved NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031889: AB_10669638, HPA031890: AB_10696056, HPA031958: AB_10601039" "unprognostic (4.66e-1)" "unprognostic (6.55e-3)" "unprognostic (1.86e-3)" "unprognostic (6.78e-3)" "unprognostic (1.16e-1)" "unprognostic (1.37e-3)" "unprognostic (8.11e-2)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (5.92e-2)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (1.58e-5)" "unprognostic (1.77e-3)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" 0.5 4.3 7.5 0.4 9.8 0.6 2.7 6.4 10.3 1.5 0.0 0.4 0.6 0.5 1.5 0.2 1.0 2.3 3.3 8.6 10.2 0.3 1.2 1.1 0.3 8.2 5.8 2.8 1.3 2.9 6.8 3.0 7.0 0.3 0.6 6.1 0.8 1.0 0.3 0.5 0.5 0.5 6.8 0.4 0.7 0.6 8.3 0.0 2.4 0.2 0.1 0.5 0.2 13.1 0.1 7.8 1.4 0.2 0.7 0.3 0.1 0.8 0.8 1.8 0.4 0.2 8.9 0.0 0.3 3.6 0.8 14.2 0.0 2.2 5.5 0.0 1.2 0.4 3.8 0.1 14.4 0.2 0.3 0.4 0.5 1.7 4.6 11.0 8.2 0.1 0.1 0.4 5.9 0.0 0.1 0.0 0.4 1.3 1.8 0.0 0.0 0.0 4.6 1.9 1.2 0.6 0.1 0.0 0.8 0.9 0.2 0.1 19.8 0.4 0.1 0.3 1.8 0.1 0.1 0.1 11.4 0.1 0.3 2.6 0.1 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 7.5 9.8 6.4 10.3 8.6 10.2 8.2 5.8 7.0 6.8 8.3 13.1 0.1 0.0 0.0 125.4 0.0 0.3 0.0 0.3 0.6 15.4 3.5 4.6 6.2 0.0 0.1 0.0 6.2 1.0 0.0 0.0 0.0 0.8 4.5 0.1 0.2 0.6 0.0 0.0 265.8 0.2 0.2 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 26.9 277.4 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 23.4 0.0 2.0 0.0 324.7 477.4 0.3 0.0 1.9 0.0 0.0 0.0 0.1 0.0 2.6 0.0 3.6 0.5 0.2 0.8 0.0 0.1 0.5 0.0 0.1 0.0 0.0 NAT8L "FLJ37478, Hcml3, Shati" ENSG00000185818 "N-acetyltransferase 8 like" Q8N9F0 4 2059327-2069089 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adipose tissue: 43.5;brain: 99.0" "Cell type enhanced" "Detected in some" "Astrocytes: 126.7;Excitatory neurons: 46.0;Horizontal cells: 80.8;Inhibitory neurons: 37.6;Muller glia cells: 25.0" "Group enriched" "Detected in many" 6 "endometrial cancer: 6.2;glioma: 17.2;melanoma: 14.6;ovarian cancer: 8.0;thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 20.8;SCLC-21H: 25.8;SK-MEL-30: 21.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040677 Approved Mitochondria NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "HPA040677: AB_2732486" "unprognostic (1.32e-2)" "unprognostic (8.62e-2)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.01e-5)" "unprognostic (2.56e-1)" "unprognostic (2.63e-4)" "unprognostic (6.58e-2)" "unprognostic (1.79e-1)" "unprognostic (2.90e-2)" "unprognostic (4.54e-1)" "unprognostic (3.70e-2)" "unprognostic (7.06e-2)" "unprognostic (1.78e-3)" "unprognostic (7.24e-3)" "unprognostic (1.14e-2)" "unprognostic (2.10e-2)" "unprognostic (1.35e-2)" 43.5 0.7 56.1 0.1 46.4 0.0 1.6 42.9 99.0 0.0 0.6 0.2 0.1 0.3 1.3 0.1 0.9 0.1 0.8 45.8 29.0 5.3 0.0 0.0 0.2 52.3 46.4 0.2 2.3 0.9 1.8 0.1 57.5 1.0 0.1 3.7 2.3 1.6 5.7 1.0 0.2 0.2 33.0 0.3 0.4 9.0 88.8 0.2 0.3 2.5 0.0 0.0 0.0 38.9 0.1 9.2 4.9 10.0 0.9 0.0 5.7 0.2 0.0 0.2 0.0 4.1 0.3 0.0 1.9 0.0 1.5 0.1 11.1 0.0 0.1 0.0 13.2 0.1 2.1 6.6 1.5 14.5 6.9 0.0 0.2 0.0 0.0 1.8 0.0 3.4 11.5 0.0 0.4 6.2 0.2 20.8 14.1 0.0 4.1 0.7 2.3 0.4 0.2 0.5 25.8 8.6 6.6 0.0 21.4 0.8 0.7 8.3 0.0 0.0 3.3 0.1 5.6 0.0 0.0 0.2 0.0 6.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 56.1 46.4 42.9 99.0 45.8 29.0 52.3 46.4 57.5 33.0 88.8 38.9 0.5 0.0 0.0 126.7 0.0 0.3 0.0 0.0 0.0 14.5 1.4 2.2 2.6 0.0 0.0 1.8 6.2 0.0 5.4 0.0 0.0 4.6 1.1 1.7 0.1 0.4 1.8 0.0 46.0 0.6 0.1 0.2 0.0 1.0 0.0 21.9 0.0 0.0 0.8 80.8 37.6 0.0 0.0 0.0 0.3 3.8 0.0 0.7 10.6 17.8 0.0 25.0 0.0 23.1 15.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.0 0.0 0.8 0.5 1.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 NCALD ENSG00000104490 "Neurocalcin delta" P61601 8 101686542-102124907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 100.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 251.6;Inhibitory neurons: 460.2;Oligodendrocyte precursor cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 87.3" "Group enriched" "Detected in many" 13 "NK-cells: 87.3;T-cells: 42.2" "Cell line enhanced" "Detected in many" "AF22: 136.4;HDLM-2: 159.9;U-266/70: 39.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043245 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043245: AB_2678385" "unprognostic (3.49e-1)" "unprognostic (1.55e-1)" "unprognostic (4.85e-2)" "unprognostic (4.97e-2)" "unprognostic (5.48e-3)" "unprognostic (2.60e-3)" "unprognostic (1.25e-1)" "unprognostic (5.63e-3)" "unprognostic (1.54e-1)" "unprognostic (2.48e-1)" "prognostic favorable (5.30e-4)" "unprognostic (2.79e-1)" "unprognostic (6.24e-2)" "unprognostic (9.16e-3)" "unprognostic (1.55e-1)" "unprognostic (7.87e-2)" "unprognostic (1.00e-2)" 21.4 7.3 30.3 9.4 43.4 1.8 44.0 0.0 62.5 13.5 0.0 22.3 6.0 7.6 4.4 12.6 39.6 12.6 12.1 52.4 11.3 14.9 15.1 19.7 13.6 3.6 13.3 37.5 10.0 1.9 13.7 10.0 15.3 12.3 8.8 15.9 100.6 14.9 15.4 18.0 10.2 11.0 1.2 8.3 11.2 7.3 29.4 5.5 5.2 11.6 11.1 11.1 4.0 21.6 6.9 9.8 136.4 0.5 1.1 22.3 0.0 2.3 0.3 0.1 0.0 0.1 0.1 9.0 3.0 10.4 0.6 0.0 1.0 0.0 0.0 159.9 1.0 0.7 0.0 0.0 0.0 6.1 0.9 4.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 19.3 0.8 0.2 1.2 2.4 1.5 0.0 0.0 3.7 0.0 0.4 22.0 0.3 0.6 13.4 0.0 3.1 5.7 22.5 0.9 4.8 0.2 1.6 0.3 0.2 0.4 39.3 5.6 0.1 0.3 0.1 2.2 0.4 0.3 0.3 42.2 0.2 37.1 0.9 16.0 24.8 5.0 0.6 3.9 20.6 1.3 87.3 0.3 0.4 17.5 13.6 30.3 43.4 0.0 62.5 52.4 11.3 3.6 13.3 15.3 1.2 29.4 21.6 17.3 0.0 2.6 11.8 0.5 4.2 0.5 1.0 0.0 14.6 88.6 74.4 7.5 14.3 3.2 0.0 25.0 3.2 28.9 1.7 7.9 9.6 12.8 32.2 5.0 11.3 21.0 4.0 251.6 1.2 13.0 39.8 4.1 23.8 2.5 20.5 14.6 15.0 1.9 13.5 460.2 4.3 61.1 2.6 6.9 6.6 2.8 2.8 103.2 75.9 0.8 46.6 64.9 281.0 26.5 3.5 0.5 1.5 7.1 1.3 0.0 19.5 26.0 4.7 26.3 91.0 24.5 1.5 1.8 3.0 3.1 3.0 17.4 19.4 0.4 1.1 NCAPD2 "CAP-D2, CNAP1, hCAP-D2, KIAA0159" ENSG00000010292 "Non-SMC condensin I complex subunit D2" Q15021 12 6493356-6531955 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 76.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 48.0;Late spermatids: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012423, HPA036947, HPA037363" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA Yes 34000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Nucleoplasm, Nucleoli" "CAB012423: , HPA036947: AB_10671367, HPA037363: AB_10672483" "unprognostic (1.51e-1)" "unprognostic (1.88e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-2)" "unprognostic (1.03e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (1.79e-8)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (5.00e-2)" "unprognostic (5.41e-3)" "unprognostic (4.53e-1)" "prognostic unfavorable (1.13e-7)" "unprognostic (4.80e-3)" "unprognostic (1.18e-1)" "unprognostic (4.53e-1)" "unprognostic (8.75e-2)" 8.3 7.4 7.3 21.5 11.4 35.5 10.9 9.9 8.3 10.2 7.4 17.9 17.0 10.7 10.6 15.9 11.2 9.8 7.6 7.2 8.0 7.4 4.8 10.6 38.1 11.0 10.0 8.0 7.7 11.3 5.5 17.5 11.7 9.4 20.4 11.1 11.8 10.2 7.9 21.9 16.0 13.4 8.4 16.1 12.1 18.2 10.2 76.8 11.3 10.2 44.8 10.1 9.3 13.9 125.3 99.3 134.6 97.9 29.9 28.4 159.2 76.1 69.8 138.3 109.1 123.5 150.8 135.8 24.2 63.2 126.7 128.6 188.0 105.4 194.1 214.1 92.8 112.2 113.8 79.4 12.5 145.0 96.5 20.5 31.6 112.4 107.8 61.9 89.9 94.0 71.0 63.4 104.7 79.6 162.2 73.8 207.5 129.9 78.2 153.7 260.6 77.7 39.5 64.1 54.0 61.9 121.5 64.9 44.3 189.1 27.0 101.7 51.0 94.1 149.6 60.8 168.4 45.3 51.7 181.0 55.7 92.2 126.1 11.0 1.7 3.7 7.1 2.8 5.3 5.1 6.4 7.3 3.4 3.5 7.3 7.3 1.4 8.1 2.2 4.1 8.3 3.9 7.3 11.4 9.9 8.3 7.2 8.0 11.0 10.0 11.7 8.4 10.2 13.9 4.3 6.4 7.4 4.9 11.0 3.6 3.8 4.4 17.1 3.7 4.7 6.9 4.1 5.7 3.4 1.8 8.4 13.5 8.9 7.3 0.0 4.5 18.3 5.3 6.3 5.4 1.2 48.0 5.6 3.7 17.8 6.4 7.1 5.8 3.8 20.0 8.9 3.3 10.1 5.0 5.0 9.9 6.1 16.4 4.4 34.3 5.9 10.8 0.0 2.8 9.5 11.8 15.5 2.5 17.8 5.3 4.6 6.0 22.6 4.1 6.0 2.4 4.2 8.4 0.0 4.2 5.2 21.3 13.7 19.3 3.4 6.3 12.0 6.1 14.7 4.1 NCAPG "CAP-G, FLJ12450, hCAP-G, YCG1" ENSG00000109805 "Non-SMC condensin I complex subunit G" Q9BPX3 4 17810979-17844865 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.9;lymphoid tissue: 15.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Extravillous trophoblasts: 26.6;Plasma cells: 20.4;Spermatocytes: 63.7;Spermatogonia: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.6" "Low region specificity" "Detected in all" HPA039613 Uncertain NA Yes 9500 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA039613: AB_10805481" "unprognostic (5.23e-2)" "unprognostic (3.37e-1)" "unprognostic (1.59e-3)" "prognostic unfavorable (8.28e-4)" "unprognostic (4.22e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (1.18e-3)" "unprognostic (1.63e-2)" "unprognostic (6.70e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.44e-2)" "unprognostic (0.00e+0)" "unprognostic (1.94e-2)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" 0.7 0.5 0.1 4.1 0.1 13.9 0.9 0.5 0.1 0.7 0.2 3.0 3.8 0.6 0.0 3.5 0.2 0.9 0.3 0.0 0.2 0.2 0.7 0.6 8.7 0.6 1.2 0.2 0.2 0.1 0.1 3.0 0.7 0.3 2.4 0.3 0.7 0.0 0.2 3.5 3.2 1.0 1.2 2.1 1.9 5.6 0.3 15.8 0.3 0.1 8.7 1.2 1.0 0.2 45.1 28.3 63.8 42.2 4.0 7.8 23.1 56.8 22.2 55.0 55.8 36.3 26.8 66.8 11.3 16.0 47.6 19.9 54.5 22.1 74.8 30.5 27.0 53.6 37.3 29.8 0.2 38.4 20.3 1.5 1.5 40.7 18.6 8.8 27.9 28.9 53.1 74.1 55.0 13.4 44.1 36.9 32.8 26.1 27.9 42.8 57.4 28.0 16.6 13.9 50.0 29.7 51.2 10.9 15.7 27.2 25.6 21.3 23.2 52.5 23.6 30.0 78.9 23.2 23.3 56.1 21.7 39.1 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.4 0.1 0.1 0.5 0.1 0.0 0.2 0.6 1.2 0.7 1.2 0.3 0.2 0.3 0.0 1.1 0.0 3.3 2.4 0.6 1.9 1.2 0.2 0.6 0.6 0.2 0.0 0.8 0.0 0.0 11.7 1.6 2.9 0.0 0.1 15.8 0.9 1.9 1.7 1.8 59.3 0.2 0.0 26.6 3.8 7.1 2.3 1.3 14.2 2.2 0.5 9.5 0.0 0.4 3.1 2.0 2.6 2.9 9.5 0.6 3.7 1.8 1.0 0.7 0.3 3.1 0.5 0.5 0.2 0.1 0.0 20.4 0.4 0.2 0.0 0.0 0.2 0.0 0.2 4.3 63.7 24.3 11.0 1.1 2.2 3.7 0.7 5.6 1.3 NCAPG2 "CAP-G2, FLJ20311, hCAP-G2, LUZP5, MTB" ENSG00000146918 "Non-SMC condensin II complex subunit G2" Q86XI2 7 158631169-158704804 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 24.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026631, HPA049637" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear speckles" "HPA026631: AB_1845983, HPA049637: " "unprognostic (2.73e-2)" "unprognostic (1.77e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (7.94e-4)" "unprognostic (1.66e-1)" "prognostic favorable (1.91e-4)" "prognostic unfavorable (3.00e-5)" "unprognostic (5.33e-3)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.79e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.19e-2)" "prognostic unfavorable (4.06e-5)" "unprognostic (2.58e-3)" "unprognostic (1.28e-1)" "unprognostic (8.21e-2)" "unprognostic (7.37e-2)" 3.7 2.5 2.0 8.8 2.2 24.4 5.4 2.5 2.1 4.0 1.3 6.9 4.4 4.3 2.1 6.9 3.0 2.9 2.9 2.2 2.1 2.6 4.1 3.1 12.4 2.0 1.7 3.1 2.2 4.6 3.5 5.9 2.1 2.8 7.6 2.8 3.5 2.8 3.4 6.8 5.8 4.8 1.6 4.6 5.6 14.8 1.8 27.9 3.2 4.1 13.8 4.0 3.9 2.4 103.9 53.7 64.1 41.8 9.5 15.4 25.3 74.3 47.4 89.0 99.0 48.5 52.0 64.0 45.0 30.3 95.1 51.7 53.7 33.8 117.2 68.4 40.4 57.2 64.8 38.8 4.2 72.2 62.3 6.8 3.7 73.1 21.0 16.2 50.4 72.9 71.9 91.6 82.8 111.4 119.2 48.8 63.7 58.8 43.3 69.7 67.8 60.6 22.6 45.9 69.6 54.5 91.6 35.0 20.2 40.4 31.4 46.5 25.9 60.6 45.9 166.2 120.6 61.3 48.2 77.2 64.6 89.6 118.5 5.9 0.9 1.1 5.2 1.2 7.5 1.6 5.2 3.6 2.3 1.0 1.6 1.8 0.7 5.2 5.1 1.1 7.2 2.2 2.0 2.2 2.5 2.1 2.2 2.1 2.0 1.7 2.1 1.6 1.8 2.4 3.6 6.4 1.5 3.9 4.1 4.0 2.1 2.8 1.8 3.9 3.7 3.3 4.8 2.8 4.6 1.8 0.0 6.7 5.1 3.4 0.0 2.3 15.1 4.0 4.6 4.3 0.0 19.6 10.7 3.3 10.4 4.5 4.1 5.9 1.3 12.6 2.9 2.6 7.3 8.4 7.2 2.9 2.0 3.8 5.2 7.2 2.8 4.4 1.8 3.7 2.7 2.1 2.1 10.1 10.7 2.3 0.4 4.1 11.0 1.1 0.3 1.3 6.0 2.8 6.6 4.3 5.7 48.2 18.5 6.1 2.0 2.6 4.9 5.0 5.7 3.0 NCAPH "BRRN1, CAP-H, hCAP-H" ENSG00000121152 "Non-SMC condensin I complex subunit H" Q15003 2 96335766-96377091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.2;lymphoid tissue: 37.4;testis: 35.4" "Cell type enhanced" "Detected in many" "Plasma cells: 26.3;Spermatocytes: 89.3;Spermatogonia: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 3.8;T-cells: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA002647, HPA003008" Enhanced Supported Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoplasm "HPA002647: AB_1078300, HPA003008: AB_1078301" "unprognostic (5.52e-2)" "unprognostic (7.37e-2)" "unprognostic (2.93e-2)" "unprognostic (2.85e-3)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "prognostic unfavorable (9.53e-6)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.50e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-2)" "unprognostic (0.00e+0)" "unprognostic (3.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (2.30e-2)" 1.2 0.7 0.3 9.9 0.4 35.2 1.8 0.9 0.9 1.3 0.1 7.7 5.6 0.9 0.2 6.3 0.5 1.6 0.4 0.3 0.2 0.4 1.0 1.1 20.3 0.1 0.0 0.3 0.3 0.5 0.2 5.2 0.3 0.4 9.3 1.8 1.5 0.2 0.3 4.7 6.2 2.8 0.0 3.7 3.6 35.4 0.1 37.4 0.4 0.1 22.0 2.6 2.0 0.3 134.1 52.0 115.1 60.6 3.9 6.1 80.8 58.7 40.3 115.1 118.4 93.5 71.5 121.0 41.8 26.6 106.2 57.2 100.2 39.6 117.2 110.0 63.4 123.7 49.3 74.5 0.7 112.2 101.3 1.8 4.2 89.1 35.9 10.2 46.6 89.7 89.5 88.8 53.0 59.5 183.8 104.2 85.9 57.6 56.6 133.4 106.7 95.5 23.6 49.6 71.2 52.3 34.8 46.5 19.9 42.4 36.6 80.0 24.1 83.5 126.3 76.9 101.9 44.4 70.1 134.0 33.7 111.5 95.3 3.8 0.0 0.2 0.8 0.9 0.1 0.9 1.2 1.0 0.4 0.9 0.0 0.4 0.3 0.1 0.0 0.0 6.2 0.5 0.3 0.4 0.9 0.9 0.3 0.2 0.1 0.0 0.3 0.0 0.1 0.3 4.9 0.0 0.0 0.0 3.5 0.6 0.7 1.9 1.2 0.4 1.0 0.8 0.5 0.0 1.6 0.0 8.4 9.4 2.0 2.1 0.0 0.5 5.9 1.7 0.9 1.8 0.0 16.4 0.4 0.0 16.3 1.8 4.1 1.2 1.3 5.5 1.4 0.4 8.5 0.0 0.3 2.8 0.0 3.8 3.7 4.9 0.9 2.2 1.8 0.0 0.2 8.5 0.0 0.5 1.0 0.2 0.1 0.4 26.3 0.7 0.4 0.0 1.6 2.3 0.0 0.2 3.5 89.3 29.4 8.8 0.9 1.9 5.1 0.6 5.7 1.1 NCCRP1 "FBXO50, LOC342897, NCCRP-1" ENSG00000188505 "NCCRP1, F-box associated domain containing" Q6ZVX7 19 39196964-39201884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 453.4;skin 1: 273.2;vagina: 181.7" "Cell type enriched" "Detected in some" 12 "monocytes: 563.9" "Group enriched" "Detected in many" 4 "cervical cancer: 42.8;head and neck cancer: 48.5;melanoma: 28.3;urothelial cancer: 33.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cell line enriched" "Detected in some" 10 "SK-BR-3: 30.8" "Region enhanced" "Detected in single" "olfactory bulb: 1.6" "Low region specificity" "Detected in some" HPA052812 Approved NA NA 400000 "Cluster 17: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "HPA052812: AB_2681960" "unprognostic (3.56e-3)" "unprognostic (3.69e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.59e-3)" "unprognostic (3.73e-3)" "unprognostic (2.78e-1)" "unprognostic (3.37e-3)" "unprognostic (1.00e-1)" "unprognostic (3.53e-3)" "unprognostic (2.04e-2)" "unprognostic (1.90e-1)" "unprognostic (6.37e-6)" "unprognostic (2.12e-1)" "unprognostic (3.00e-1)" "unprognostic (2.13e-1)" "unprognostic (1.57e-1)" 0.3 0.2 1.3 2.1 0.9 1.0 6.3 1.9 1.8 97.0 0.0 0.4 2.0 0.6 0.8 453.4 1.1 0.8 0.4 1.0 0.8 2.8 0.2 0.4 2.7 1.0 0.9 0.4 8.8 1.4 0.4 1.1 1.3 1.4 1.9 1.7 54.0 1.2 0.9 273.2 0.7 0.5 0.9 1.4 0.5 0.5 1.0 4.1 0.6 0.0 124.9 5.2 181.7 1.4 0.2 0.2 1.1 0.2 0.1 0.7 2.4 0.1 0.0 0.1 0.2 0.5 0.5 0.7 2.3 0.4 0.2 1.0 1.7 0.7 0.5 0.0 0.4 0.2 0.9 0.1 0.2 0.5 0.3 0.5 0.5 0.1 0.3 0.3 0.3 0.5 0.4 0.2 0.3 0.1 0.2 0.2 0.7 0.2 0.2 0.2 0.4 0.4 0.1 0.6 0.6 1.0 2.9 30.8 0.2 0.9 0.4 0.9 0.2 0.2 0.2 0.2 0.5 0.2 0.2 0.6 0.6 0.2 0.5 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 1.3 0.9 1.9 1.8 1.0 0.8 1.0 0.9 1.3 0.9 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.6 1.6 8.5 0.0 0.3 4.7 2.4 0.3 0.0 30.8 3.7 0.0 0.4 0.2 0.1 0.0 2.7 0.0 0.7 0.4 0.2 0.0 0.0 0.0 2.3 3.1 1.0 0.0 2.5 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 6.1 0.0 4.7 0.2 0.0 0.7 1.8 0.0 563.9 0.3 0.0 0.0 0.0 4.2 0.7 0.0 1.2 1.1 0.0 0.1 1.6 0.0 0.0 0.1 2.0 0.1 0.5 7.3 7.1 11.1 0.2 0.1 0.0 46.4 NCOA6 "AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP" ENSG00000198646 "Nuclear receptor coactivator 6" Q14686 20 34689097-34825651 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 130.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004198, HPA050211" Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004198: AB_1078228, HPA050211: AB_2681052" "unprognostic (2.48e-1)" "unprognostic (4.81e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.65e-4)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.87e-2)" "unprognostic (1.51e-1)" "prognostic favorable (8.78e-5)" "unprognostic (9.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.42e-2)" 10.2 9.0 5.2 9.1 6.7 14.0 9.2 12.7 12.4 10.8 4.8 12.9 13.2 10.7 12.2 11.7 11.3 8.8 9.2 6.1 8.2 9.9 8.4 10.4 8.9 6.3 4.6 11.6 12.6 22.0 10.0 13.5 4.6 9.8 14.5 26.7 12.9 11.3 12.7 13.5 12.0 13.2 2.3 9.4 11.4 18.8 7.4 18.1 13.8 13.1 10.3 10.4 10.5 9.6 25.2 14.7 32.6 19.7 17.5 19.4 21.3 12.0 15.3 21.1 16.9 37.9 17.2 17.7 12.9 21.5 25.8 30.0 29.3 20.2 23.9 9.0 13.2 41.6 16.7 22.4 19.3 23.5 29.4 14.8 36.5 19.8 24.5 14.6 20.2 20.1 21.5 23.7 17.7 16.3 37.5 14.8 6.7 21.0 21.1 24.9 39.3 15.9 15.6 16.6 27.2 18.5 22.0 52.5 20.5 15.0 22.2 18.5 20.0 34.1 20.7 25.6 20.2 26.9 24.3 20.0 22.5 13.5 15.5 1.1 0.6 2.5 0.9 0.5 0.8 1.0 0.8 0.8 1.1 0.8 0.7 0.5 1.5 0.7 0.7 1.0 0.5 0.5 5.2 6.7 12.7 12.4 6.1 8.2 6.3 4.6 4.6 2.3 7.4 9.6 17.3 25.6 16.0 54.9 11.0 17.0 9.1 10.6 13.6 28.8 14.3 10.9 20.1 18.6 11.6 16.5 29.2 13.0 12.2 31.9 5.9 12.5 23.5 16.4 21.3 14.0 10.8 13.3 50.9 12.4 12.1 14.5 15.8 23.3 6.3 18.5 13.9 12.1 10.8 33.7 58.8 17.4 20.3 12.2 10.3 17.3 18.0 13.0 10.6 45.9 17.6 11.5 13.4 54.3 130.4 15.4 12.4 13.5 14.2 16.9 20.3 9.3 17.5 29.8 26.3 16.6 16.9 25.6 27.1 19.2 20.9 15.9 13.1 13.6 17.6 14.6 NDC80 "HEC, HEC1, hsNDC80, KNTC2, TID3" ENSG00000080986 "NDC80 kinetochore complex component" O14777 18 2571557-2616635 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.2;lymphoid tissue: 29.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 63.4;Spermatocytes: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 7.2;granulocytes: 8.3;T-cells: 11.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA066330 Supported Nucleoplasm,Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Centrosome "HPA066330: AB_2685661" "unprognostic (1.96e-1)" "unprognostic (5.38e-2)" "unprognostic (2.96e-1)" "unprognostic (2.21e-3)" "unprognostic (1.87e-1)" "unprognostic (3.63e-2)" "prognostic unfavorable (2.53e-8)" "unprognostic (1.16e-2)" "unprognostic (2.58e-3)" "unprognostic (2.86e-2)" "unprognostic (3.19e-3)" "unprognostic (7.74e-2)" "unprognostic (0.00e+0)" "unprognostic (9.69e-3)" "unprognostic (1.69e-1)" "unprognostic (3.50e-2)" "unprognostic (1.71e-1)" 1.8 0.9 1.4 9.6 1.3 31.2 2.5 2.2 1.7 2.7 0.1 7.0 5.9 4.3 2.1 5.6 1.2 2.5 1.2 1.0 0.6 1.2 1.6 1.5 20.5 1.9 0.6 0.8 0.9 0.5 0.1 10.4 2.9 5.3 9.8 0.7 1.1 14.0 0.9 7.9 6.2 5.0 0.4 5.5 3.8 15.1 1.2 29.2 1.6 0.6 19.3 3.2 4.6 2.5 80.3 17.7 86.5 38.6 4.5 9.8 44.5 91.7 49.1 117.7 99.7 49.2 44.0 86.6 40.4 35.9 49.7 47.9 98.2 39.9 123.6 32.2 24.6 68.8 49.5 38.1 1.5 133.2 55.1 5.1 3.7 67.8 47.8 12.0 54.3 52.8 56.8 107.1 104.0 36.2 65.1 57.2 44.9 51.6 25.3 71.0 88.6 69.7 31.0 38.0 69.3 31.4 84.4 21.7 32.7 34.0 36.7 52.4 33.2 75.7 168.1 60.7 123.2 46.5 78.6 116.0 33.5 60.8 65.8 3.5 0.6 2.5 1.8 0.4 1.7 7.2 3.2 3.8 0.2 5.3 2.0 2.0 8.3 1.7 0.5 1.3 11.3 1.3 1.4 1.3 2.2 1.7 1.0 0.6 1.9 0.6 2.9 0.4 1.2 2.5 2.8 0.0 0.6 0.3 5.8 2.3 0.7 3.8 0.6 0.0 0.6 0.9 15.8 0.0 2.4 0.0 0.0 15.5 4.8 2.1 0.0 0.9 22.0 1.3 3.7 1.9 0.0 63.4 0.6 0.4 21.7 6.8 2.6 2.1 0.0 20.8 5.7 0.5 11.5 0.0 0.5 2.8 8.2 3.2 2.4 7.6 7.5 1.7 0.0 1.0 0.4 0.0 7.2 0.5 0.5 0.3 0.1 23.3 14.1 0.4 0.4 0.2 1.4 0.0 19.7 0.6 6.8 82.8 21.1 4.2 0.6 2.1 8.7 9.8 6.2 1.5 NDE1 "FLJ20101, NDE, nudE" ENSG00000072864 "NudE neurodevelopment protein 1" Q9NXR1 16 15643267-15734691 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein" Lissencephaly "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 21.8;monocytes: 11.7;NK-cells: 8.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024075 Approved NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA024075: AB_1854336" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (3.26e-1)" "unprognostic (1.47e-1)" "unprognostic (3.84e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.43e-2)" "unprognostic (1.59e-1)" "unprognostic (4.55e-2)" "unprognostic (3.70e-3)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.29e-1)" "unprognostic (3.28e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" 9.2 5.8 12.1 13.0 23.6 25.6 9.4 22.5 15.6 14.6 6.9 25.0 7.5 11.6 2.6 17.7 11.1 9.8 10.6 11.2 16.1 6.3 4.2 11.1 20.4 30.0 24.5 7.5 4.0 4.0 3.1 10.0 26.5 14.2 7.3 2.0 12.2 5.1 7.3 27.6 12.9 10.7 17.0 12.5 10.1 11.1 21.3 23.4 6.3 7.9 20.9 15.3 19.8 43.2 37.0 33.0 34.2 39.9 11.4 18.6 10.4 15.4 21.0 30.4 34.5 18.3 58.3 21.9 24.0 23.2 16.7 34.5 25.3 47.3 20.8 33.7 16.0 24.6 35.3 51.7 16.3 33.3 37.2 6.6 28.9 28.8 52.0 16.9 40.6 27.9 20.5 80.5 26.6 43.9 43.0 30.5 30.5 26.5 14.3 64.8 32.3 34.8 11.6 24.1 17.0 21.0 27.5 40.7 27.6 25.9 42.8 34.3 12.5 26.9 17.6 43.2 36.1 17.4 13.1 38.1 27.5 43.0 55.0 5.1 4.7 15.0 3.0 3.8 1.7 3.3 3.0 1.3 3.4 1.9 1.8 2.0 21.8 8.5 11.7 3.1 3.3 3.9 12.1 23.6 22.5 15.6 11.2 16.1 30.0 24.5 26.5 17.0 21.3 43.2 11.7 3.2 4.4 11.1 36.1 26.0 32.7 19.0 24.5 7.0 9.5 10.4 2.0 4.3 8.9 5.5 6.2 3.9 25.0 9.6 0.0 4.5 46.9 17.1 23.1 11.6 4.2 49.0 2.1 5.3 5.3 11.8 19.4 15.0 10.8 15.5 8.6 1.7 10.1 3.3 2.4 7.4 2.0 15.8 11.0 58.5 15.8 19.3 12.4 22.5 53.0 7.4 50.4 9.5 105.5 7.1 4.2 6.0 16.6 26.3 4.6 1.9 13.3 6.5 6.6 6.9 9.5 13.8 10.0 18.8 30.7 2.5 28.3 9.8 10.2 21.6 NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481124-79556075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 342.7;Late spermatids: 290.4;Suprabasal keratinocytes: 367.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.1;eosinophil: 22.7;naive CD4 T-cell: 5.6" "Group enriched" "Detected in many" 16 "granulocytes: 22.7;T-cells: 5.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA009160: AB_1079456" "unprognostic (2.56e-1)" "unprognostic (5.51e-3)" "unprognostic (1.95e-3)" "unprognostic (9.61e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (2.30e-1)" "unprognostic (3.12e-1)" "unprognostic (1.52e-2)" "unprognostic (2.63e-2)" "prognostic favorable (4.18e-5)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" 13.9 19.2 17.0 11.4 20.9 2.6 22.7 10.0 25.2 15.5 7.0 42.7 52.7 10.1 22.5 54.4 17.1 20.1 26.0 27.1 8.1 45.9 46.3 17.7 13.0 10.1 7.3 7.0 31.8 29.6 6.4 31.9 12.3 22.7 47.0 21.7 21.4 15.6 30.9 71.3 64.3 9.1 10.6 11.7 25.9 18.1 9.2 16.0 19.3 19.9 19.6 35.6 25.2 21.5 134.6 22.6 23.2 29.4 27.7 50.3 43.6 48.5 66.9 50.1 83.0 49.9 146.1 5.6 32.6 64.0 28.5 178.2 20.5 84.9 75.3 69.7 57.1 6.2 66.5 27.1 50.5 106.2 17.8 40.4 109.3 33.4 52.7 55.8 24.1 10.4 27.5 10.0 56.8 19.3 8.7 24.1 17.1 109.7 22.7 0.5 45.7 25.2 123.1 76.7 23.3 33.4 54.9 52.4 40.0 37.8 43.8 88.2 20.4 16.0 20.4 31.1 32.8 37.6 44.2 21.1 65.6 0.5 65.6 12.1 0.0 22.7 3.2 0.0 2.7 0.2 2.8 2.6 0.0 0.6 5.6 3.1 0.1 0.8 0.0 0.2 3.2 2.4 17.0 20.9 10.0 25.2 27.1 8.1 10.1 7.3 12.3 10.6 9.2 21.5 17.5 41.7 28.9 26.4 4.4 342.7 137.0 180.6 118.4 30.9 32.7 18.8 29.4 57.2 93.2 47.8 6.2 112.6 6.9 161.0 23.5 85.6 271.2 51.5 17.2 22.0 69.4 4.2 189.0 72.2 152.7 33.2 31.1 49.8 88.2 11.5 20.7 69.2 14.4 16.8 44.2 88.1 95.6 17.0 23.5 290.4 17.4 4.0 33.8 27.2 2.7 22.8 5.2 42.3 100.3 101.7 96.7 12.8 13.8 105.6 204.3 104.6 112.6 15.5 13.1 22.2 24.0 56.5 45.1 102.2 367.7 109.7 24.9 35.2 73.3 145.5 NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 236.4;Peritubular cells: 207.6;Theca cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 55.0;ASC diff: 52.9;HSkMC: 71.3;NTERA-2: 44.0;SuSa: 57.4;U-2 OS: 80.4;U-266/70: 51.7;U-266/84: 51.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA074457: AB_2686691" "unprognostic (3.49e-1)" "unprognostic (1.65e-1)" "unprognostic (4.20e-1)" "unprognostic (2.19e-2)" "unprognostic (2.71e-1)" "unprognostic (9.04e-2)" "unprognostic (6.79e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (1.89e-2)" "unprognostic (8.10e-2)" "unprognostic (1.96e-1)" "unprognostic (6.81e-2)" 46.8 49.4 43.3 11.1 40.5 1.2 35.1 26.0 39.7 70.5 30.4 35.9 11.1 63.7 24.0 16.8 47.2 23.8 34.6 36.7 89.6 13.0 4.5 19.6 10.9 36.0 41.3 69.8 11.8 8.7 56.3 32.6 46.2 27.3 10.7 20.8 12.7 39.3 14.7 11.9 20.8 33.5 36.7 19.1 20.3 18.5 69.6 6.8 17.4 22.4 6.6 31.4 40.4 32.3 0.1 0.0 55.0 0.0 52.9 20.1 0.1 35.4 0.0 0.8 9.6 0.0 0.0 0.0 0.1 10.6 8.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.3 0.0 31.8 71.3 0.0 10.2 0.0 0.0 0.0 21.7 1.2 0.0 18.0 0.0 27.6 0.1 44.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.1 0.4 0.0 0.4 0.0 57.4 9.4 0.0 0.0 2.6 80.4 0.0 0.1 51.7 51.7 0.0 5.5 0.0 0.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 1.5 0.0 0.0 43.3 40.5 26.0 39.7 36.7 89.6 36.0 41.3 46.2 36.7 69.6 32.3 24.1 25.6 11.0 6.8 0.3 13.0 13.8 0.3 27.9 66.0 2.3 19.8 36.8 15.7 1.4 12.9 20.9 1.9 2.9 18.5 23.5 17.9 2.5 1.4 60.8 18.7 6.7 4.2 7.8 10.7 1.4 103.1 4.1 1.1 0.0 83.9 38.9 0.2 7.3 50.5 21.8 4.3 0.0 7.6 13.3 8.6 236.4 2.8 39.2 9.4 0.7 88.7 0.0 9.5 16.4 4.5 2.6 207.6 0.0 6.9 8.1 1.1 4.1 51.0 98.6 91.4 94.0 28.5 21.8 13.4 8.2 2.5 1.4 121.8 7.1 4.1 NDRG2 "KIAA1248, SYLD" ENSG00000165795 "NDRG family member 2" Q9UN36 14 21016763-21070872 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1885.3;salivary gland: 2081.6;skeletal muscle: 1828.7" "Cell type enhanced" "Detected in many" "Astrocytes: 379.0;Distal tubular cells: 485.2;Muller glia cells: 548.0;Sertoli cells: 598.2" "Cancer enhanced" "Detected in all" "glioma: 78.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "myeloid DC: 204.4" "Lineage enriched" "Detected in all" 11 "dendritic cells: 204.4" "Cell line enhanced" "Detected in many" "Hep G2: 57.0;HMC-1: 39.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002896, HPA003590, CAB017491" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 460000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "Centriolar satellite" "Nucleoplasm, Cytosol" "CAB017491: AB_2298331, HPA002896: AB_1079459, HPA003590: AB_1079458" "unprognostic (9.27e-3)" "unprognostic (2.97e-3)" "unprognostic (1.26e-2)" "unprognostic (5.09e-3)" "unprognostic (2.00e-2)" "unprognostic (2.92e-2)" "prognostic favorable (6.71e-4)" "unprognostic (1.85e-3)" "unprognostic (5.57e-2)" "unprognostic (3.46e-2)" "unprognostic (1.69e-1)" "unprognostic (5.10e-2)" "prognostic favorable (1.43e-12)" "unprognostic (1.46e-1)" "unprognostic (5.56e-2)" "unprognostic (6.11e-2)" "unprognostic (4.19e-2)" 192.0 400.6 1613.1 27.4 1885.3 2.8 321.6 1623.2 1666.4 395.4 1189.8 198.3 72.1 229.7 260.3 229.5 305.0 130.7 327.2 1551.7 1590.0 150.1 544.4 115.5 48.6 1690.6 1686.1 476.1 93.7 278.5 88.5 45.3 1581.9 171.3 111.0 134.1 2081.6 208.0 1828.7 220.3 125.4 127.7 1584.5 152.0 130.9 33.3 1752.7 40.1 99.9 1591.4 100.4 158.0 265.8 1597.9 10.9 2.3 6.8 12.6 1.1 0.0 1.0 0.2 4.5 3.9 2.2 15.1 20.0 0.6 4.0 0.3 6.2 17.6 30.3 6.3 5.4 0.1 10.9 14.3 2.2 57.0 1.3 1.3 39.0 11.8 13.1 0.9 1.9 6.3 0.0 12.6 29.0 1.2 0.6 9.4 5.0 4.0 17.9 35.2 0.8 14.6 0.7 3.7 7.6 27.4 0.1 19.4 3.0 3.3 14.4 17.3 26.6 8.2 0.0 1.2 20.8 0.4 0.4 6.1 4.8 0.3 1.8 0.3 4.7 0.0 6.5 0.7 8.3 1.5 11.4 6.4 12.6 11.9 204.4 4.4 18.7 14.0 1.4 3.0 0.1 7.0 9.4 15.3 1613.1 1885.3 1623.2 1666.4 1551.7 1590.0 1690.6 1686.1 1581.9 1584.5 1752.7 1597.9 98.0 0.0 11.9 379.0 6.7 28.7 83.7 86.4 12.0 6.3 240.7 201.2 180.2 151.5 110.9 40.5 10.4 11.5 9.1 81.4 485.2 104.9 6.3 33.3 11.0 53.9 33.5 8.4 1.1 21.7 0.7 62.3 18.8 40.2 48.8 79.0 164.2 214.9 20.7 3.3 3.9 77.4 57.0 30.8 137.6 14.4 348.6 30.4 321.9 47.8 8.7 548.0 1.0 42.7 71.0 16.3 37.9 166.3 1.2 68.5 18.5 41.3 70.8 15.5 598.2 167.7 162.8 1.7 5.5 21.6 30.4 21.6 11.9 66.8 118.9 155.9 NDUFC2 "B14.5b, HLC-1" ENSG00000151366 "NADH:ubiquinone oxidoreductase subunit C2" O95298 11 78068297-78079862 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038873, HPA056195" Approved Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA038873: AB_10673480, HPA056195: AB_2683063" "unprognostic (7.32e-2)" "unprognostic (5.91e-3)" "unprognostic (4.00e-2)" "unprognostic (6.14e-2)" "unprognostic (1.94e-1)" "unprognostic (8.97e-2)" "unprognostic (1.60e-1)" "unprognostic (4.23e-3)" "unprognostic (4.75e-3)" "unprognostic (3.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "prognostic favorable (5.00e-5)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (4.18e-2)" "unprognostic (3.61e-3)" 202.3 278.0 118.8 84.5 126.1 126.1 143.0 128.7 150.7 103.0 125.6 143.6 218.4 125.3 68.4 142.6 120.2 108.6 240.7 129.0 145.8 151.1 286.8 100.0 109.1 121.6 117.1 96.2 168.8 186.1 133.5 74.8 124.2 88.7 66.1 59.8 275.1 83.2 487.6 121.9 194.3 63.6 136.8 96.2 130.0 103.0 126.1 73.5 207.0 254.0 62.8 97.1 100.1 136.3 287.6 342.2 183.3 118.8 168.3 105.6 227.2 335.7 190.9 252.4 179.9 910.4 311.8 166.3 583.3 155.8 210.2 293.1 136.1 190.9 99.5 318.8 386.7 183.8 337.4 727.9 270.9 409.7 164.2 147.9 177.8 195.6 75.2 156.0 172.9 158.8 365.3 278.4 137.9 478.7 254.5 722.4 212.4 670.4 415.6 224.5 352.5 570.5 196.4 420.7 261.2 229.0 235.0 499.5 182.3 158.8 391.4 328.2 241.0 256.4 314.9 611.8 297.9 251.5 541.9 400.4 146.4 236.6 251.0 374.5 337.6 354.0 150.1 293.0 138.3 230.8 172.4 163.4 363.5 212.1 144.5 159.8 102.2 225.4 243.0 290.4 202.7 410.9 118.8 126.1 128.7 150.7 129.0 145.8 121.6 117.1 124.2 136.8 126.1 136.3 256.6 166.7 194.7 0.0 106.4 95.5 166.1 443.7 40.5 145.8 346.2 414.0 240.9 243.1 288.2 391.8 66.7 408.8 166.4 206.3 305.2 395.6 311.8 413.8 129.3 183.7 167.9 106.5 0.0 431.5 392.8 165.7 43.3 241.7 153.2 158.1 184.9 856.9 346.2 90.9 0.0 317.9 429.3 174.5 110.7 84.7 215.6 129.4 245.5 0.0 246.7 310.0 175.1 0.0 0.0 456.5 329.1 201.6 102.5 239.0 461.8 454.6 300.0 131.6 236.7 154.5 222.7 384.4 162.1 67.5 114.4 387.1 109.9 226.3 373.2 215.6 NECAP2 FLJ10420 ENSG00000157191 "NECAP endocytosis associated 2" Q9NVZ3 1 16440721-16460078 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 314.8;monocytes: 202.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028077 Approved Approved "Endoplasmic reticulum" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Endoplasmic reticulum" "HPA028077: AB_10601273" "unprognostic (6.92e-2)" "unprognostic (4.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.73e-2)" "unprognostic (1.28e-1)" "unprognostic (4.35e-1)" "prognostic unfavorable (6.13e-4)" "unprognostic (5.48e-2)" "unprognostic (1.57e-1)" "unprognostic (3.38e-1)" "unprognostic (6.72e-2)" "unprognostic (1.70e-1)" "unprognostic (4.36e-2)" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" "unprognostic (5.58e-2)" "unprognostic (2.58e-2)" 38.1 37.9 28.4 51.7 31.0 29.0 34.3 30.7 32.8 31.6 29.5 30.9 23.4 22.8 19.2 43.5 32.8 30.5 22.2 27.0 30.4 33.2 31.7 51.7 77.6 34.6 29.5 36.8 22.1 23.7 19.8 59.9 31.5 25.4 29.5 14.2 26.6 21.0 8.6 45.7 32.0 30.2 32.0 73.3 30.5 33.7 32.5 55.9 25.7 12.8 63.3 44.4 31.1 32.7 54.1 29.2 30.5 36.0 60.6 65.0 17.9 59.6 83.3 76.8 67.9 32.1 87.1 47.8 70.4 111.2 35.4 35.8 43.1 60.3 63.9 100.0 44.3 46.7 33.4 44.6 78.9 59.8 41.7 73.0 61.6 54.7 44.9 66.2 129.1 54.4 67.0 153.7 69.1 35.3 55.8 63.3 26.6 41.1 41.9 61.2 27.0 79.6 76.9 30.5 19.1 48.6 46.4 27.1 61.9 45.1 30.9 66.1 148.0 49.2 26.8 57.4 41.1 72.5 74.5 47.9 41.6 85.7 49.0 90.2 173.1 112.3 96.1 241.2 95.6 108.8 165.8 114.5 120.1 98.8 168.2 106.6 68.2 121.6 274.7 71.0 214.7 269.9 28.4 31.0 30.7 32.8 27.0 30.4 34.6 29.5 31.5 32.0 32.5 32.7 53.6 22.4 25.0 10.1 47.6 52.3 34.1 60.4 27.3 25.7 37.9 35.1 7.0 22.8 32.2 20.2 314.8 49.0 42.5 34.6 23.5 71.3 61.1 27.0 29.5 67.8 18.7 40.8 7.0 54.2 62.0 33.3 23.9 27.6 27.8 33.0 96.4 11.0 125.7 15.2 7.7 31.8 36.7 94.5 81.8 34.3 29.8 60.5 24.9 7.5 202.0 23.8 55.6 11.6 11.4 121.9 45.8 33.8 24.3 46.6 30.8 22.8 37.4 54.3 39.5 14.7 27.2 26.8 27.4 33.3 56.0 49.4 59.4 72.7 24.0 58.8 NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.9;skin 1: 113.6;vagina: 57.3" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 384.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 56.5;HaCaT: 37.0;MCF7: 24.0;OE19: 24.6;SK-BR-3: 47.8;T-47d: 31.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" No No 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" 0.4 0.1 0.1 0.5 0.1 0.7 13.7 0.3 0.2 26.5 0.0 1.5 0.7 1.2 6.9 98.9 2.9 3.8 0.1 0.1 0.0 3.1 0.1 3.5 0.1 0.1 0.1 0.0 4.5 0.4 0.6 12.2 0.1 9.4 1.7 0.1 33.6 4.3 0.6 113.6 0.6 0.1 0.0 0.0 8.8 0.6 0.3 0.8 0.2 0.0 14.5 16.8 57.3 0.4 10.9 0.4 0.0 0.1 0.0 0.1 56.5 0.1 0.1 0.1 0.2 0.0 14.6 0.0 0.2 0.0 0.1 37.0 0.0 1.2 0.2 0.0 0.5 0.0 0.8 11.1 0.0 0.1 0.7 0.0 14.6 3.0 3.6 0.1 0.0 0.0 0.0 0.1 0.1 24.0 0.1 0.1 0.1 24.6 0.0 0.0 0.0 0.1 0.0 17.5 0.0 0.2 0.2 47.8 0.0 6.4 31.1 0.0 0.0 0.1 2.4 0.5 0.2 0.2 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.2 6.4 9.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.6 17.8 0.0 0.0 8.1 16.5 0.0 39.4 0.4 0.0 0.0 41.7 0.0 28.1 2.9 0.6 0.0 0.0 0.0 30.0 67.1 1.2 0.0 43.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 67.1 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 384.2 0.4 0.1 0.0 0.0 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "NEDD4 like E3 ubiquitin protein ligase" Q96PU5 18 58044226-58401540 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.2;Excitatory neurons: 280.9" "Cancer enhanced" "Detected in all" "prostate cancer: 29.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "T-reg: 5.1" "Lineage enriched" "Detected in many" 4 "T-cells: 5.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 146.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 11.2 16.8 20.9 6.7 34.4 27.0 25.8 25.1 31.3 7.6 0.7 38.8 18.7 5.3 10.0 12.0 9.1 9.5 26.9 32.3 16.2 53.4 36.5 47.9 4.1 10.9 18.4 6.4 60.5 13.6 28.4 12.0 10.4 64.2 42.8 20.5 27.5 20.4 34.0 11.2 33.8 6.2 8.6 7.9 51.5 7.8 16.7 4.5 17.4 13.1 7.9 19.4 5.9 16.3 70.7 24.5 14.6 20.9 5.1 2.1 49.8 19.2 88.2 48.6 74.6 28.6 37.1 15.1 57.7 7.4 51.3 50.3 19.5 86.1 100.8 34.9 15.5 10.6 14.3 111.3 2.4 0.5 6.0 13.0 54.6 66.4 78.8 39.1 4.0 13.2 18.7 6.3 20.0 16.2 1.0 1.0 12.2 26.7 33.3 14.3 20.1 17.6 47.0 88.7 17.5 5.0 16.1 5.1 146.1 28.3 29.4 5.6 28.8 131.5 38.5 7.5 83.4 8.3 15.3 9.5 27.6 10.8 10.8 0.7 0.3 1.2 0.2 0.3 0.5 0.8 0.6 0.1 0.1 0.3 0.3 0.2 0.2 0.3 0.1 0.1 5.1 0.3 20.9 34.4 25.1 31.3 32.3 16.2 10.9 18.4 10.4 8.6 16.7 16.3 6.0 253.2 144.8 110.4 5.1 112.8 161.2 34.0 86.6 18.1 99.5 65.9 47.8 64.3 112.8 62.5 173.0 13.0 3.6 144.5 49.0 35.7 22.6 64.0 7.3 14.7 45.2 57.9 280.9 49.2 4.7 9.5 114.7 75.0 3.8 4.7 17.5 41.3 7.3 62.2 173.3 201.5 101.7 8.4 8.2 6.6 3.4 13.3 14.2 88.1 7.3 45.2 2.1 11.1 105.0 49.9 145.3 17.7 12.7 126.9 127.3 91.6 72.7 10.0 0.0 34.3 6.0 1.1 12.5 62.3 53.0 80.0 6.6 8.2 72.9 155.5 NEDD9 "CAS-L, CASS2, HEF1" ENSG00000111859 "Neural precursor cell expressed, developmentally down-regulated 9" Q14511 6 11183298-11382348 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Growth regulation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 323.2;Alveolar cells type 1: 471.1;Glandular and luminal cells: 337.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 137.3;HSkMC: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009689, CAB009720, HPA038768, HPA039270, HPA072955" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009720: , HPA009689: , HPA038768: AB_2676196, HPA039270: AB_2676422, HPA072955: " "unprognostic (2.83e-3)" "unprognostic (2.33e-2)" "unprognostic (1.08e-2)" "unprognostic (6.93e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "unprognostic (3.05e-2)" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.64e-1)" "unprognostic (5.59e-3)" "unprognostic (2.25e-2)" "unprognostic (2.37e-1)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" 94.7 8.6 8.3 23.3 8.1 8.6 64.2 6.4 12.3 26.6 14.4 30.7 15.5 19.2 17.5 14.5 22.7 31.4 32.7 7.7 6.4 33.8 20.7 91.9 25.8 8.3 7.3 8.3 17.1 9.5 8.1 69.2 8.5 22.4 30.2 9.8 26.7 29.8 27.2 20.6 38.1 25.8 7.4 25.2 23.5 6.9 9.7 22.2 25.6 12.0 22.2 34.5 15.3 7.9 4.4 29.0 26.4 0.4 17.7 2.3 27.7 6.6 8.2 12.2 22.4 9.3 1.9 9.2 137.3 14.7 1.5 12.6 36.0 13.5 15.8 4.1 1.0 0.8 4.4 62.3 8.3 10.1 0.4 67.7 4.0 7.9 1.3 4.4 21.0 0.8 0.1 7.6 27.7 1.3 5.8 4.0 4.1 34.6 2.9 1.6 0.7 5.4 6.1 39.8 0.6 4.8 1.1 31.2 55.5 29.3 2.3 7.7 53.8 8.2 14.3 0.8 16.5 7.8 34.8 11.4 0.2 7.9 36.6 24.2 13.3 37.3 18.3 28.5 14.7 10.9 12.2 17.5 14.1 12.3 6.4 9.9 80.9 12.3 50.6 8.7 12.1 17.1 8.3 8.1 6.4 12.3 7.7 6.4 8.3 7.3 8.5 7.4 9.7 7.9 323.2 471.1 135.1 11.1 34.9 60.5 235.6 83.5 98.4 4.7 43.1 38.0 14.2 50.1 89.0 44.1 25.0 56.3 45.9 103.4 9.8 62.0 8.2 244.8 24.8 148.1 108.3 2.5 18.2 19.8 42.6 37.2 107.6 337.0 64.5 15.7 86.7 21.6 14.7 10.1 11.3 108.4 12.2 29.8 28.9 4.3 7.5 51.4 24.9 34.7 15.4 84.1 64.9 8.0 4.9 69.1 43.6 29.0 34.8 66.1 100.5 26.7 64.4 12.4 26.3 8.8 30.0 2.1 1.1 11.4 20.6 42.8 59.4 37.2 46.6 90.3 NEFM "NEF3, NF-M, NFM" ENSG00000104722 "Neurofilament medium" P07197 8 24913758-24919098 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 689.9" "Cell type enhanced" "Detected in many" "Early spermatids: 92.6;Excitatory neurons: 46.6;Late spermatids: 114.6;Rod photoreceptor cells: 69.1;Spermatocytes: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 25 "HEK 293: 3890.8" "CAB010900, CAB012976, HPA022845, HPA023138" Enhanced Enhanced "Intermediate filaments" Yes NA 220000 "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Intermediate filaments" "CAB010900: AB_477261, CAB012976: AB_2533154, HPA022845: AB_1854399, HPA023138: AB_1854398" "unprognostic (1.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.59e-2)" "unprognostic (9.38e-2)" "unprognostic (5.17e-2)" "unprognostic (6.32e-3)" "unprognostic (6.10e-3)" "unprognostic (2.57e-1)" "unprognostic (8.55e-3)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-2)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (4.76e-2)" "unprognostic (2.61e-2)" 0.3 19.5 61.1 0.9 27.9 0.0 0.1 150.0 689.9 9.6 0.0 2.8 0.1 4.0 0.0 4.0 5.3 0.2 0.2 57.7 54.0 1.9 0.1 0.2 0.1 610.3 89.1 1.7 2.0 0.0 17.9 0.2 487.1 1.5 0.7 90.8 0.3 27.6 1.7 0.6 1.3 2.5 86.8 0.1 0.9 18.9 430.5 1.7 0.1 0.7 0.5 0.4 6.5 203.6 0.0 0.0 154.3 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3890.8 0.0 0.0 0.0 79.4 0.0 0.1 2.4 0.1 0.6 0.0 0.0 0.0 0.7 0.0 0.2 5.9 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 3.7 32.6 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 27.9 150.0 689.9 57.7 54.0 610.3 89.1 487.1 86.8 430.5 203.6 3.1 0.0 0.0 12.4 0.0 1.3 0.2 0.1 9.1 30.9 1.1 21.2 2.4 0.0 0.6 0.0 6.2 0.0 3.2 0.1 0.0 0.1 92.6 0.7 19.5 2.9 3.5 0.0 46.6 0.2 0.0 2.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 20.2 17.5 0.0 0.0 0.0 0.7 114.6 0.9 0.7 1.8 13.1 0.0 22.8 0.0 9.5 13.6 0.0 0.0 4.5 0.4 0.3 0.0 0.4 0.0 69.1 0.0 3.3 5.7 43.8 1.0 14.0 0.3 0.0 4.1 0.0 0.1 0.4 NEIL2 "FLJ31644, MGC2832, MGC4505, NEH2" ENSG00000154328 "Nei like DNA glycosylase 2" Q969S2 8 11769639-11787345 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 68.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA073029, HPA073916" Supported Nucleoplasm,Vesicles NA NA "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA073029: AB_2732216, HPA073916: AB_2732245" "unprognostic (1.52e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (9.88e-2)" "unprognostic (2.18e-2)" "unprognostic (5.72e-2)" "unprognostic (2.70e-1)" "unprognostic (2.88e-2)" "unprognostic (5.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.99e-3)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (5.29e-2)" "unprognostic (1.91e-1)" "unprognostic (2.09e-1)" "unprognostic (4.05e-1)" 9.5 27.8 29.2 5.9 28.8 2.3 9.5 27.7 27.9 13.1 23.8 8.6 2.8 9.5 12.5 6.9 15.0 5.7 14.6 29.6 35.6 12.8 16.3 7.4 7.1 32.0 34.3 11.1 11.2 9.0 17.9 6.4 36.8 11.3 4.8 13.4 10.0 8.1 24.5 15.8 6.8 8.5 31.9 12.4 6.9 26.1 36.1 4.7 11.8 13.7 6.9 9.8 8.8 28.3 8.2 22.9 14.1 27.7 6.6 12.2 6.3 13.0 10.6 12.2 8.4 7.1 8.8 3.2 4.9 15.7 26.3 7.1 13.5 14.1 16.7 9.7 6.7 11.3 5.7 13.9 5.3 5.0 8.2 10.8 20.7 10.7 9.9 11.8 11.6 3.7 16.1 10.8 15.0 8.6 0.9 5.2 12.6 33.9 12.1 14.4 18.1 8.8 14.4 12.3 21.5 17.0 10.2 5.3 19.1 11.2 8.4 0.7 14.3 13.9 19.8 3.8 18.4 10.0 22.3 5.7 36.6 16.7 28.8 0.7 2.2 0.2 12.7 3.9 17.5 21.9 12.9 15.3 4.6 16.9 18.7 16.8 1.3 15.1 2.0 8.3 9.3 7.0 29.2 28.8 27.7 27.9 29.6 35.6 32.0 34.3 36.8 31.9 36.1 28.3 7.2 0.0 5.8 6.2 14.0 8.5 17.1 8.0 13.6 32.3 13.1 7.7 19.6 14.3 7.0 7.3 16.7 18.6 5.6 1.5 33.2 21.1 1.1 6.9 8.4 8.9 10.1 10.3 6.3 23.3 15.8 10.3 3.1 3.8 2.5 14.9 7.9 23.6 15.1 8.4 6.9 6.1 14.2 6.9 6.6 2.1 14.0 6.8 14.2 0.0 6.6 38.9 11.3 6.0 3.7 15.1 1.0 24.5 3.8 15.3 0.8 32.2 6.8 17.1 6.6 11.8 10.2 19.0 68.1 8.3 12.8 5.3 9.7 8.9 6.2 12.0 NEIL3 "FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3" ENSG00000109674 "Nei like DNA glycosylase 3" Q8TAT5 4 177309874-177362936 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.6;lymphoid tissue: 23.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 14.7;Granulosa cells: 4.8;Plasma cells: 6.1;Squamous epithelial cells: 4.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 72.1;HL-60: 79.1;Karpas-707: 99.1;MOLT-4: 80.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.3" HPA065761 Enhanced Nucleoplasm NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA065761: AB_2685555" "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.45e-4)" "unprognostic (4.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.64e-7)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (6.51e-4)" "unprognostic (2.82e-3)" "unprognostic (0.00e+0)" "unprognostic (3.25e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-2)" 0.1 0.0 0.0 1.7 0.0 6.6 0.3 0.0 0.1 0.2 0.0 1.1 1.1 0.1 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 2.3 1.3 0.5 0.0 0.4 0.6 1.5 0.1 23.6 0.0 0.0 3.5 0.4 0.4 0.0 19.3 15.8 16.4 8.2 1.8 3.3 8.0 23.4 8.6 25.3 14.9 5.8 16.5 21.2 3.4 6.2 25.1 8.8 17.4 9.3 36.6 72.1 11.4 14.7 11.9 15.2 0.5 79.1 9.7 0.3 0.5 26.2 5.6 5.2 9.9 53.9 15.3 99.1 16.7 8.4 80.7 30.2 7.5 5.7 11.5 16.2 11.2 6.8 6.8 2.6 12.8 8.9 11.7 13.4 6.3 7.2 10.9 20.4 4.7 15.2 11.8 7.8 24.0 6.8 4.8 33.5 10.1 27.8 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.1 0.4 1.2 0.0 0.2 0.1 0.4 0.0 1.3 0.0 0.0 2.6 1.6 0.5 0.0 0.0 0.1 0.1 0.6 0.3 0.0 14.7 0.1 0.2 3.3 0.9 0.0 0.5 0.0 4.8 0.4 0.0 1.5 0.0 0.1 1.0 0.0 1.3 0.4 0.2 0.0 1.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 6.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.5 2.7 2.4 4.5 1.3 0.3 1.0 0.5 1.2 0.2 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 17.9;lymphoid tissue: 19.2;testis: 67.1" "Group enriched" "Detected in many" 4 "Early spermatids: 76.1;Spermatocytes: 244.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.7" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: AB_2685393" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (9.47e-6)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 0.7 0.4 0.5 5.3 0.4 17.9 1.5 0.9 0.6 1.1 0.6 5.9 7.4 1.3 0.5 4.4 2.2 0.8 0.4 0.5 0.3 0.3 0.7 0.7 9.0 0.4 0.2 0.4 0.1 0.1 0.0 3.2 0.3 2.5 7.6 1.5 0.8 0.2 0.4 4.3 6.9 2.0 0.2 1.7 2.7 67.1 0.6 19.2 0.4 0.2 10.6 1.3 1.6 0.9 86.0 60.5 45.3 32.6 2.6 4.5 49.7 32.4 30.1 55.4 47.5 32.3 81.7 45.1 15.2 25.2 35.1 44.5 39.9 24.2 69.6 69.5 33.2 21.6 51.4 44.2 0.4 43.2 28.3 1.4 2.9 42.9 45.9 13.4 36.3 45.2 59.9 76.9 56.0 23.6 47.3 28.8 43.0 55.0 30.5 46.2 69.2 68.7 19.7 24.2 41.0 45.0 46.6 51.5 39.3 38.4 79.4 25.1 19.0 27.6 54.1 54.8 88.3 31.6 62.6 59.6 24.1 32.6 46.8 1.2 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.0 0.4 0.3 0.2 0.7 1.5 0.1 0.2 1.6 0.3 0.5 0.4 0.9 0.6 0.5 0.3 0.4 0.2 0.3 0.2 0.6 0.9 0.1 0.0 0.5 0.3 1.7 2.9 0.7 3.8 0.6 11.3 1.9 2.2 0.5 0.0 2.9 0.0 0.0 9.4 0.8 1.9 0.0 0.2 76.1 15.2 0.7 0.8 0.0 39.6 0.8 0.2 14.1 1.4 5.6 1.5 0.0 3.6 3.6 0.7 5.8 3.3 0.0 3.2 10.2 2.5 1.1 39.0 2.5 2.1 0.0 0.0 0.0 1.6 2.1 0.0 0.1 0.0 2.5 0.7 5.4 0.7 2.1 0.1 5.2 1.8 6.6 0.0 1.5 244.2 26.1 8.6 1.7 1.4 2.0 0.9 9.5 1.4 NEK6 SID6-1512 ENSG00000119408 "NIMA related kinase 6" Q9HC98 9 124257606-124353307 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 121.0;Hofbauer cells: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045993, HPA056828" Approved Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "Centriolar satellite" "CAB045993: AB_2150651, HPA056828: AB_2683250" "unprognostic (6.27e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (1.65e-2)" "unprognostic (5.22e-2)" "unprognostic (2.47e-2)" "unprognostic (3.13e-3)" "unprognostic (2.13e-2)" "unprognostic (2.38e-1)" "unprognostic (3.30e-2)" "unprognostic (1.38e-3)" "unprognostic (6.53e-2)" "unprognostic (5.03e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (5.27e-2)" "unprognostic (4.77e-3)" 18.0 6.1 33.5 32.6 34.3 19.6 14.7 28.1 32.4 26.1 26.5 22.3 17.5 12.2 3.4 8.5 11.2 25.4 7.4 31.8 37.0 17.2 68.2 24.3 27.4 49.8 41.2 9.0 16.7 1.9 6.1 30.2 33.9 19.6 22.5 11.3 20.6 16.7 8.2 5.4 25.8 18.7 34.4 16.6 27.1 7.8 44.2 10.2 7.3 3.1 31.7 24.3 6.4 30.4 31.8 50.0 47.8 18.8 88.3 113.9 59.3 38.8 61.1 58.4 48.4 47.7 57.0 38.2 61.0 74.6 133.2 5.9 24.7 111.7 39.4 43.7 21.8 104.4 42.1 85.4 105.2 19.4 250.0 152.8 17.8 55.4 56.9 152.3 64.3 17.6 19.5 1.7 105.6 32.6 0.9 20.8 12.2 163.7 45.5 40.6 35.6 19.6 62.6 11.4 21.4 7.5 12.6 23.6 54.5 48.3 51.4 76.4 127.5 42.2 42.8 29.5 26.7 8.4 11.4 21.6 53.5 42.3 57.5 28.1 47.6 76.4 9.2 32.1 5.9 52.5 5.5 7.8 29.0 30.2 0.9 3.8 58.8 23.3 41.4 26.9 7.6 21.6 33.5 34.3 28.1 32.4 31.8 37.0 49.8 41.2 33.9 34.4 44.2 30.4 8.4 9.6 4.7 37.9 24.5 2.4 13.8 18.9 4.6 1.0 9.4 6.5 3.3 18.6 8.8 3.7 0.0 47.1 11.3 8.5 1.9 41.3 18.2 9.4 17.7 8.4 6.0 4.0 8.3 23.3 121.0 11.1 19.4 22.2 22.2 1.1 5.0 43.5 112.0 0.0 5.3 18.2 18.3 10.4 22.5 20.0 5.0 31.2 7.2 12.2 57.7 34.6 8.2 15.1 2.4 30.6 11.9 3.8 5.5 17.1 17.2 38.0 3.3 2.1 0.0 4.9 6.4 1.3 17.1 2.4 1.1 36.1 4.5 2.1 18.7 10.2 NELFA "NELF-A, WHSC2" ENSG00000185049 "Negative elongation factor complex member A" Q9H3P2 4 1982717-2041903 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009960, HPA039858, HPA043931" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear bodies" "CAB009960: AB_2288566, HPA039858: AB_2676711, HPA043931: AB_2678737" "unprognostic (1.66e-1)" "unprognostic (2.23e-1)" "unprognostic (3.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.32e-1)" "unprognostic (1.73e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (2.40e-1)" "unprognostic (1.12e-1)" "unprognostic (9.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.88e-3)" "unprognostic (1.58e-1)" "unprognostic (3.76e-2)" "unprognostic (2.77e-1)" "unprognostic (2.43e-1)" "unprognostic (3.05e-2)" 9.3 7.8 7.5 10.8 8.6 14.2 6.0 8.0 11.5 7.1 6.1 9.4 13.4 11.3 6.3 9.5 12.4 5.7 6.3 8.0 6.9 6.8 5.8 6.6 10.8 8.7 8.9 15.5 16.7 10.1 3.0 10.3 6.8 8.9 4.7 7.0 18.2 8.4 12.0 12.8 13.4 5.7 8.1 12.1 12.7 16.5 7.4 9.4 7.4 4.6 7.4 6.8 1.8 9.5 27.2 24.6 21.0 38.8 8.5 8.9 41.6 14.3 10.1 16.9 13.4 41.1 45.7 47.8 20.1 9.3 21.0 25.2 21.3 17.9 8.2 24.5 33.2 31.5 18.0 39.4 12.4 33.1 30.9 7.6 15.6 11.3 12.0 12.5 13.0 26.6 60.5 22.3 7.4 31.7 63.8 94.4 60.8 23.2 36.5 57.6 18.3 30.2 12.1 22.5 57.1 35.7 16.4 19.3 24.4 13.0 37.1 24.5 14.7 17.0 19.2 19.8 31.9 47.2 52.7 53.6 19.4 34.5 21.4 7.0 14.4 14.9 15.4 16.9 18.5 16.3 17.9 13.9 13.9 24.0 15.0 12.0 5.3 15.4 14.0 17.3 22.1 13.1 7.5 8.6 8.0 11.5 8.0 6.9 8.7 8.9 6.8 8.1 7.4 9.5 11.1 12.8 17.9 30.7 18.5 32.6 18.6 20.3 17.6 19.2 17.6 19.3 4.6 14.3 19.1 12.9 39.6 27.9 16.2 14.6 9.8 18.7 24.0 25.2 17.7 13.2 16.2 17.2 55.9 13.6 28.1 14.7 13.3 28.5 9.5 23.3 11.4 8.3 16.4 37.0 40.9 17.8 14.2 10.1 12.1 7.4 15.5 11.3 14.2 13.1 19.6 18.1 19.6 31.7 30.2 16.2 18.7 13.2 14.0 23.6 17.5 8.9 17.3 21.9 0.0 15.4 15.2 32.9 39.4 29.8 38.2 28.5 18.8 15.8 20.1 27.0 NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.5;choroid plexus: 59.5;fallopian tube: 60.1;retina: 85.2" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 652.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 33.3" "Group enriched" "Detected in many" 15 "amygdala: 48.9;basal ganglia: 60.0;cerebral cortex: 105.5;hippocampal formation: 89.6;white matter: 42.0" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.4;naive CD8 T-cell: 111.1" "Lineage enriched" "Detected in many" 10 "T-cells: 111.1" "Cell line enhanced" "Detected in some" "AF22: 104.6;HEK 293: 27.5;NTERA-2: 41.2;SCLC-21H: 75.6;U-266/70: 27.5;U-266/84: 29.5;U-698: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" NA NA 6400000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035714: AB_2674746, HPA035715: AB_10669602" "unprognostic (4.25e-3)" "unprognostic (4.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (7.18e-2)" "unprognostic (5.85e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (1.71e-5)" "unprognostic (8.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.75e-2)" 4.6 16.9 48.9 10.9 60.0 7.3 1.9 1.3 105.5 23.1 59.5 2.0 26.3 2.2 0.4 1.2 60.1 1.9 0.4 89.6 4.5 1.2 1.0 5.0 20.7 0.0 0.0 0.8 0.9 0.2 34.6 0.3 0.0 27.2 2.1 85.2 1.4 2.0 0.3 13.4 15.3 2.8 0.0 6.2 2.9 3.0 0.8 8.7 6.5 0.6 15.7 4.1 4.2 42.0 0.3 0.1 104.6 3.5 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 8.3 12.4 0.0 0.0 0.2 25.3 0.2 0.0 0.0 27.5 0.4 8.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.1 1.6 0.2 0.4 0.0 0.4 0.2 0.4 41.2 0.0 14.0 0.2 12.7 0.2 0.0 0.0 75.6 1.8 0.0 0.4 0.0 1.3 0.1 0.7 0.0 0.4 3.8 0.1 2.1 27.5 29.5 40.3 0.2 0.2 0.4 0.2 0.2 0.0 5.0 0.1 24.9 0.2 30.3 52.9 0.1 0.1 70.4 111.1 0.5 11.0 0.1 0.1 0.4 26.7 48.9 60.0 1.3 105.5 89.6 4.5 0.0 0.0 0.0 0.0 0.8 42.0 0.3 0.0 1.3 48.0 1.0 1.1 0.0 0.0 5.7 35.4 0.4 0.6 0.5 2.8 6.2 0.0 33.3 0.1 2.5 5.8 0.0 0.0 0.4 0.7 0.8 0.7 0.0 0.0 652.4 0.2 0.3 3.7 0.0 0.3 0.0 49.4 0.0 0.0 0.1 1.7 108.4 0.9 0.0 0.0 1.5 1.0 0.0 0.4 0.0 18.7 1.3 7.9 1.0 74.4 16.5 0.4 0.4 0.4 0.5 0.3 18.5 0.2 21.9 58.3 0.0 4.1 4.6 1.9 4.2 0.2 1.1 0.1 23.4 0.1 2.9 0.1 NEURL3 "Lincr, LOC93082, RNF132" ENSG00000163121 "Neuralized E3 ubiquitin protein ligase 3" Q96EH8 2 96497646-96508109 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 16.2;pancreas: 25.1;salivary gland: 30.3" "Group enriched" "Detected in many" 4 "Ductal cells: 114.6;Exocrine glandular cells: 36.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.8;CAPAN-2: 15.6;GAMG: 5.5;RPMI-8226: 10.1;RT4: 4.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (4.97e-2)" "unprognostic (6.07e-2)" "unprognostic (7.22e-2)" "unprognostic (1.42e-2)" "unprognostic (2.49e-2)" "unprognostic (4.35e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (2.29e-1)" "unprognostic (9.55e-2)" "unprognostic (1.18e-2)" "unprognostic (1.06e-1)" "unprognostic (8.14e-3)" "unprognostic (1.23e-2)" "unprognostic (5.83e-2)" "unprognostic (6.57e-2)" "unprognostic (2.44e-1)" "unprognostic (6.57e-4)" 0.1 0.0 0.8 0.4 0.8 0.3 1.9 0.6 0.9 0.1 0.5 0.7 1.6 0.1 0.1 0.1 0.2 2.1 0.2 0.8 0.7 16.2 2.5 2.5 0.2 0.8 0.7 0.0 25.1 0.0 0.3 0.0 0.8 3.9 0.5 0.1 30.3 2.5 0.1 0.6 2.1 0.0 0.7 0.6 0.5 0.4 0.7 4.8 0.0 0.0 0.3 0.4 0.0 0.9 1.0 0.5 0.0 0.3 0.0 0.0 3.8 0.0 0.4 0.3 0.2 2.3 15.6 0.0 1.2 0.0 5.5 2.3 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 10.1 2.1 4.7 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.8 0.8 0.6 0.9 0.8 0.7 0.8 0.7 0.8 0.7 0.7 0.9 0.4 0.0 1.5 0.7 0.9 0.0 10.2 0.0 0.0 0.0 7.6 8.3 0.4 11.5 0.6 9.2 0.0 0.3 0.3 6.9 3.9 114.6 0.0 4.9 0.2 1.0 2.4 3.2 0.4 36.5 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.2 1.1 0.0 0.1 1.4 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 12.2 0.8 0.0 0.0 0.1 17.8 5.2 0.0 0.0 13.2 10.6 5.8 0.0 0.0 0.0 0.0 0.4 0.7 1.9 0.0 0.0 0.0 0.2 1.4 1.2 5.9 NFE2 NF-E2 ENSG00000123405 "Nuclear factor, erythroid 2" Q16621 12 54292111-54301015 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 112.5;lymphoid tissue: 45.3" "Cell type enriched" "Detected in some" 5 "Erythroid cells: 265.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 1489.2;neutrophil: 810.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 1489.2" "Group enriched" "Detected in some" 5 "HEL: 376.9;K-562: 168.1;NB-4: 118.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA001914 Enhanced Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Actin filaments" "HPA001914: AB_1079475" "unprognostic (2.68e-4)" "unprognostic (2.93e-2)" "unprognostic (2.20e-2)" "unprognostic (2.31e-2)" "unprognostic (2.33e-2)" "unprognostic (1.85e-1)" "unprognostic (1.20e-2)" "unprognostic (4.55e-2)" "unprognostic (4.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-3)" "unprognostic (9.90e-6)" "unprognostic (1.81e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-2)" "unprognostic (3.46e-2)" 3.8 0.3 0.5 6.2 0.7 112.5 0.6 0.5 1.0 1.4 1.4 0.4 0.5 0.3 0.1 0.8 2.4 1.2 1.9 0.5 0.5 1.4 2.6 13.0 0.3 0.7 0.6 0.2 0.7 1.1 0.9 4.0 0.7 0.5 0.2 0.0 0.5 0.1 1.3 4.8 0.6 1.9 0.5 45.3 0.8 1.2 0.6 1.4 1.4 3.7 0.1 2.3 0.5 0.6 0.3 0.3 0.0 0.0 0.0 0.5 1.4 1.1 6.9 0.7 0.9 5.5 10.0 0.1 0.9 0.9 0.4 0.3 0.0 0.0 0.3 0.0 0.1 376.9 0.9 9.1 0.0 5.8 48.5 0.5 0.1 0.3 0.2 4.4 0.0 0.1 168.1 0.1 0.0 0.1 15.3 118.8 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 2.6 0.2 0.6 1.8 1.0 18.9 0.3 0.2 0.4 1.1 0.1 0.0 0.0 0.1 0.4 23.4 0.0 1489.2 241.7 232.3 0.6 66.7 1.0 0.3 0.8 0.5 156.7 0.5 1.0 0.7 810.6 1.1 42.0 2.7 0.2 160.2 0.5 0.7 0.5 1.0 0.5 0.5 0.7 0.6 0.7 0.5 0.6 0.6 0.0 0.0 3.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 1.5 0.1 0.0 0.0 0.2 1.3 0.0 0.0 0.1 5.9 0.1 0.0 0.0 0.0 265.6 0.0 0.0 0.5 0.4 0.0 0.1 3.8 0.1 0.4 0.2 1.0 0.0 0.0 0.0 0.0 22.8 0.2 19.0 0.0 44.3 1.8 0.0 33.9 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.3 1.2 1.1 0.0 0.1 0.1 NFE2L2 NRF2 ENSG00000116044 "Nuclear factor, erythroid 2 like 2" Q16236 2 177227595-177392697 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002990, CAB020317, HPA043438" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB020317: , HPA002990: AB_1079476, HPA043438: AB_2678482" "unprognostic (2.11e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.41e-1)" "unprognostic (5.95e-2)" "unprognostic (3.90e-1)" "unprognostic (5.27e-2)" "unprognostic (9.58e-2)" "unprognostic (3.48e-2)" "unprognostic (9.86e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "prognostic favorable (2.26e-4)" "unprognostic (1.97e-2)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (9.77e-3)" 87.0 73.6 64.8 65.4 83.9 58.9 78.3 74.9 86.7 83.2 78.7 83.4 100.1 92.6 97.2 257.0 88.5 97.7 77.6 66.5 71.6 143.5 176.6 88.5 50.4 82.0 77.5 137.3 47.3 60.4 58.4 80.4 84.5 72.7 85.8 68.2 79.7 90.5 64.4 162.3 82.9 91.8 70.4 69.0 176.9 65.2 75.7 68.2 130.4 65.9 93.8 160.7 108.7 91.8 53.1 57.3 52.2 56.4 181.4 190.2 61.7 91.8 124.9 81.4 90.5 75.9 97.9 52.8 93.8 102.8 148.4 96.9 65.1 136.7 111.5 40.8 41.1 65.9 95.9 156.3 231.2 39.3 60.6 134.0 314.5 115.5 169.3 184.4 80.9 39.7 72.7 91.4 111.8 49.8 42.3 101.9 58.8 277.2 58.9 34.0 46.5 54.6 120.9 182.1 69.0 45.0 202.9 64.8 216.6 147.8 49.1 105.0 119.9 80.4 54.5 89.5 54.7 70.1 44.7 43.1 81.6 43.3 159.4 130.6 89.3 55.4 55.2 84.3 62.9 61.8 64.0 57.0 100.4 51.9 101.2 66.8 103.2 68.1 83.0 38.8 66.6 66.0 64.8 83.9 74.9 86.7 66.5 71.6 82.0 77.5 84.5 70.4 75.7 91.8 193.3 157.0 93.5 66.3 143.3 295.8 241.8 448.4 306.7 61.3 90.0 113.7 67.9 117.2 247.0 154.5 16.7 113.2 249.1 120.7 393.2 154.5 81.4 238.1 126.9 139.6 75.6 58.0 25.3 170.8 34.5 206.6 170.7 279.9 212.7 141.5 120.0 93.2 88.1 57.2 26.6 73.5 321.4 111.6 569.9 39.0 287.7 266.0 96.0 88.1 170.6 191.4 55.6 63.8 113.0 128.3 91.8 214.0 118.8 150.5 94.9 85.0 205.9 48.4 39.5 211.8 152.4 66.1 32.1 617.9 315.4 186.2 150.6 153.5 119.6 225.2 NFX1 "MGC20369, NFX2, TEG-42, Tex42" ENSG00000086102 "Nuclear transcription factor, X-box binding 1" Q12986 9 33290512-33371157 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056310, HPA061382, HPA073519" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA056310: AB_2683097, HPA061382: AB_2684496, HPA073519: AB_2686614" "unprognostic (3.90e-2)" "unprognostic (6.01e-2)" "unprognostic (1.19e-2)" "unprognostic (1.40e-1)" "unprognostic (3.07e-2)" "unprognostic (2.02e-2)" "unprognostic (9.11e-2)" "unprognostic (1.81e-2)" "unprognostic (8.71e-2)" "prognostic favorable (3.75e-4)" "unprognostic (3.40e-2)" "unprognostic (1.27e-1)" "unprognostic (1.13e-3)" "unprognostic (3.36e-2)" "unprognostic (1.14e-2)" "unprognostic (9.62e-2)" "unprognostic (3.20e-2)" 16.8 16.8 13.7 15.6 14.5 21.9 20.6 20.4 17.6 15.5 15.9 17.1 16.9 17.4 15.7 18.3 15.4 12.4 23.4 13.8 15.0 14.6 27.7 16.0 22.3 13.7 12.8 21.9 15.8 23.4 13.5 13.5 13.5 16.5 19.1 19.4 17.9 16.0 37.7 25.5 17.5 15.7 10.9 18.2 15.8 12.2 14.0 26.3 22.9 26.5 25.2 16.8 15.7 18.2 29.8 24.0 21.4 20.3 31.3 35.1 21.5 27.6 27.4 30.6 30.5 21.7 11.9 46.0 17.0 32.0 20.5 16.3 38.8 29.8 28.4 33.9 18.9 24.1 58.2 24.5 38.1 43.3 25.6 32.7 48.9 26.1 65.4 27.3 18.9 25.6 37.6 38.3 32.2 20.9 28.3 40.7 34.7 21.9 26.8 30.0 23.3 25.2 20.7 28.1 29.3 20.6 27.5 29.3 15.9 25.1 17.0 42.7 23.8 24.8 20.6 18.1 30.4 20.4 19.9 44.6 27.3 21.5 14.4 35.9 5.5 10.4 9.8 8.9 10.5 13.0 10.7 10.8 9.0 10.3 11.8 11.9 3.5 9.3 7.4 15.4 7.6 6.7 13.7 14.5 20.4 17.6 13.8 15.0 13.7 12.8 13.5 10.9 14.0 18.2 16.0 60.9 42.5 35.3 41.9 8.4 24.6 12.5 21.6 29.3 13.2 13.5 36.9 22.8 35.4 27.6 54.2 12.5 17.2 20.6 7.9 16.1 65.9 16.7 19.0 14.9 9.1 25.2 59.7 13.2 11.8 18.5 26.5 19.8 18.9 15.7 17.5 32.4 15.0 21.9 59.0 23.9 12.2 19.4 10.2 17.0 18.3 19.0 3.6 47.8 16.4 13.7 16.5 37.7 55.0 12.4 21.6 23.0 47.1 25.3 23.3 8.2 43.7 32.2 13.1 27.3 17.5 16.1 14.8 20.9 11.2 18.1 20.9 19.2 16.7 21.0 NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.2;brain: 129.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.0;Excitatory neurons: 105.9;Proximal enterocytes: 66.7" "Cancer enhanced" "Detected in many" "testis cancer: 22.5" "Region enhanced" "Detected in many" "basal ganglia: 129.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 53.9;HDLM-2: 45.3;HeLa: 21.6;PC-3: 57.0;T-47d: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 167.6;cerebral cortex: 133.8;hippocampal formation: 73.0" HPA008160 Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA008160: AB_1854450" "unprognostic (3.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-3)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-3)" "unprognostic (5.41e-3)" "unprognostic (2.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-1)" 1.1 56.2 16.3 2.2 129.6 0.1 1.9 0.0 59.4 4.1 0.0 14.2 42.7 5.0 4.1 10.3 4.8 3.1 2.2 19.8 0.0 7.0 35.5 0.7 0.2 0.0 0.0 2.0 6.0 11.9 2.7 0.3 0.0 1.8 10.5 1.4 2.0 0.7 0.9 30.3 31.3 6.7 0.0 0.4 10.7 3.7 0.2 0.0 0.9 0.7 0.3 1.8 5.2 29.4 53.9 15.4 0.6 0.2 0.2 8.2 0.9 0.9 0.1 0.4 0.0 0.7 5.2 0.0 15.2 10.9 5.5 6.9 11.6 3.0 0.4 45.3 3.8 0.1 21.6 16.7 0.2 0.0 0.3 0.0 0.2 3.5 0.6 0.2 1.9 0.2 0.2 0.2 0.5 4.0 0.0 0.1 1.3 0.2 57.0 0.0 0.0 0.1 1.0 1.4 1.9 0.4 6.6 3.3 0.1 2.0 32.2 0.4 0.0 0.5 4.5 0.3 1.0 0.5 0.2 0.0 3.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 129.6 0.0 59.4 19.8 0.0 0.0 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 10.4 0.0 9.9 1.2 1.2 2.8 0.3 2.1 1.4 2.4 4.3 0.5 0.0 0.0 0.1 0.0 38.0 0.0 3.9 0.7 9.1 0.9 0.4 4.9 0.0 105.9 10.5 0.3 0.7 17.3 2.0 0.0 0.3 0.4 20.4 0.1 1.7 12.8 14.6 0.0 0.3 0.6 2.0 0.0 0.3 1.8 6.5 0.0 5.5 0.0 4.5 6.0 12.1 23.5 1.2 0.1 0.5 66.7 9.8 2.5 0.2 0.0 0.2 0.3 1.1 0.8 3.8 7.5 0.0 0.2 0.5 20.2 1.1 NHLH2 "bHLHa34, HEN2, NSCL2" ENSG00000177551 "Nescient helix-loop-helix 2" Q02577 1 115836377-115843917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 7.4;esophagus: 2.3;retina: 2.1;skin 1: 3.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 14.8;Oligodendrocyte precursor cells: 4.5;Oligodendrocytes: 7.9;Spermatocytes: 5.1;Squamous epithelial cells: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 58.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055238 Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 37: Myocytes - Muscle contraction" "Nuclear bodies" Nucleoplasm "HPA055238: AB_2682752" "unprognostic (2.20e-2)" "unprognostic (2.28e-1)" "unprognostic (1.97e-1)" "unprognostic (1.82e-1)" "unprognostic (2.17e-1)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "unprognostic (1.11e-2)" "unprognostic (5.26e-2)" "unprognostic (9.55e-2)" "unprognostic (2.80e-3)" "unprognostic (1.53e-1)" "unprognostic (3.09e-1)" "unprognostic (2.25e-1)" 0.0 0.0 2.0 0.0 1.4 0.0 0.1 5.9 2.1 0.3 0.2 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 3.2 4.0 0.0 0.0 0.2 0.0 3.8 5.1 0.0 0.0 0.0 0.2 0.0 7.4 0.2 0.0 2.1 0.4 0.1 0.2 3.3 0.0 0.0 2.5 0.0 0.2 0.4 6.7 0.0 0.0 0.0 0.0 0.0 0.7 3.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.4 5.9 2.1 3.2 4.0 3.8 5.1 7.4 2.5 6.7 3.0 0.0 0.0 0.0 0.3 0.0 2.8 2.8 3.3 14.8 3.9 0.0 0.6 3.4 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 1.8 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 4.5 7.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.4 0.0 3.5 0.3 5.1 3.4 7.0 2.3 0.0 0.0 0.0 0.0 0.4 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122677 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 5.0;Exocrine glandular cells: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 6.8;K-562: 6.1;SCLC-21H: 6.1" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favorable (5.30e-4)" 1.2 1.4 2.0 0.8 2.3 1.1 2.0 1.5 2.6 0.8 0.8 1.5 1.4 0.8 2.6 1.1 1.4 0.6 1.8 2.4 1.9 0.8 4.1 1.2 0.6 2.5 1.8 1.4 1.8 1.2 1.2 0.5 2.7 1.2 1.3 2.0 2.3 1.0 2.6 3.8 1.9 0.8 1.6 1.1 1.3 0.7 2.0 1.0 1.6 1.5 0.8 0.9 0.8 3.6 2.6 1.5 0.6 0.0 1.3 1.2 0.0 2.6 0.8 0.9 0.5 0.1 2.1 0.0 6.8 1.9 0.2 3.0 0.0 1.7 0.7 0.1 0.9 0.4 1.0 0.1 2.0 0.0 1.7 2.1 2.5 1.0 0.9 0.6 2.1 0.0 6.1 0.1 2.1 2.8 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.1 1.4 2.8 6.1 0.1 5.3 4.3 1.6 0.6 3.1 1.7 0.4 0.2 1.3 1.8 0.1 0.1 0.0 0.1 0.1 0.0 2.6 0.5 4.4 0.4 0.6 4.9 0.8 2.3 1.1 0.5 4.7 1.3 1.5 1.0 0.3 1.6 2.3 0.6 1.3 1.8 2.0 2.3 1.5 2.6 2.4 1.9 2.5 1.8 2.7 1.6 2.0 3.6 0.8 0.0 2.2 0.3 0.2 1.9 1.4 1.4 1.8 0.4 1.5 2.0 0.9 1.5 2.3 0.0 0.0 0.4 0.0 0.2 0.0 2.9 0.0 0.6 1.3 0.3 3.5 5.0 1.0 3.7 0.0 0.8 1.5 0.5 1.3 0.8 0.4 1.1 1.2 0.0 0.7 0.3 0.0 0.8 0.6 0.0 0.6 1.5 1.8 1.0 0.5 1.1 0.0 1.5 1.2 2.0 0.3 0.0 0.0 0.2 0.6 1.2 0.8 1.0 0.0 0.3 0.8 0.2 0.2 1.3 1.8 0.4 0.1 1.1 0.5 0.5 NHSL1 "bA43P8.1, C6orf63, KIAA1357" ENSG00000135540 "NHS like 1" Q5SYE7 6 138422043-138692571 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.2" "Cell type enriched" "Detected in many" 4 "Astrocytes: 502.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.6;non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 46.2;TIME: 64.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029966, HPA029967" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear membrane" Nucleoplasm "HPA029966: AB_10601972, HPA029967: AB_2673271" "unprognostic (1.85e-1)" "unprognostic (9.71e-2)" "unprognostic (6.19e-2)" "unprognostic (1.81e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (3.27e-1)" "unprognostic (8.34e-2)" "unprognostic (5.21e-2)" "unprognostic (9.99e-2)" "unprognostic (1.10e-1)" "unprognostic (8.00e-2)" "unprognostic (4.19e-2)" "unprognostic (3.73e-2)" "unprognostic (1.52e-1)" "unprognostic (6.55e-2)" "unprognostic (4.06e-2)" 4.1 1.2 15.7 2.4 14.1 0.3 2.5 9.7 8.5 2.4 16.6 13.2 15.8 1.2 4.6 10.4 1.0 3.0 15.7 14.6 11.2 5.8 14.8 12.8 1.0 16.2 15.9 0.5 3.3 2.1 1.1 4.3 10.7 0.8 11.4 2.6 3.5 0.5 0.5 11.4 23.2 3.2 9.2 2.6 7.8 0.4 14.4 0.6 1.4 0.8 2.1 2.7 4.5 5.6 5.5 4.7 32.8 13.8 9.4 11.4 12.2 4.8 2.3 1.7 1.6 6.2 3.1 0.0 6.0 4.1 3.1 12.3 20.0 12.5 0.9 0.4 13.4 3.4 2.2 46.2 13.8 12.4 2.3 16.7 7.0 0.9 14.1 1.8 23.3 1.9 0.0 1.8 7.2 10.7 1.3 1.0 13.1 3.1 8.8 14.1 3.4 1.0 11.2 13.7 12.4 0.0 5.1 10.3 33.4 21.5 3.3 3.9 64.3 4.6 4.5 4.6 13.3 1.2 2.7 0.0 0.4 5.0 25.5 0.4 1.2 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.2 15.7 14.1 9.7 8.5 14.6 11.2 16.2 15.9 10.7 9.2 14.4 5.6 6.2 60.9 66.9 502.1 0.5 42.8 3.1 6.6 4.0 0.6 4.1 6.0 22.7 15.7 9.9 29.5 29.2 14.2 0.1 84.1 9.8 3.7 1.1 19.0 1.8 9.3 20.3 2.7 3.3 3.6 3.5 15.6 16.8 16.9 8.8 1.5 26.4 38.1 4.5 37.0 2.9 32.3 6.1 9.4 7.1 0.4 0.6 7.5 21.4 104.0 0.6 15.4 0.0 79.9 2.3 3.9 43.0 0.0 0.1 5.4 87.3 15.8 22.0 1.4 6.6 2.3 4.7 0.0 1.1 7.7 49.2 43.4 1.8 0.8 45.4 10.5 NINJ1 NIN1 ENSG00000131669 "Ninjurin 1" Q92982 9 93121496-93134251 "Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 286.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 539.9;Langerhans cells: 741.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1668.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 1668.9" "Cell line enhanced" "Detected in many" "Hep G2: 197.5;MCF7: 191.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045063 Uncertain "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" "HPA045063: AB_10964133" "unprognostic (1.23e-2)" "unprognostic (8.25e-3)" "unprognostic (3.64e-3)" "unprognostic (1.40e-2)" "unprognostic (8.18e-2)" "unprognostic (1.28e-2)" "unprognostic (4.29e-2)" "unprognostic (5.88e-2)" "unprognostic (6.82e-2)" "unprognostic (9.06e-2)" "unprognostic (1.93e-1)" "unprognostic (1.74e-2)" "unprognostic (9.45e-3)" "unprognostic (2.51e-1)" "unprognostic (2.69e-2)" "unprognostic (1.40e-3)" "unprognostic (7.46e-3)" 60.9 129.8 51.0 39.9 48.9 286.9 53.0 47.9 58.7 47.6 50.2 60.1 27.0 36.5 20.2 25.7 47.6 39.2 64.0 44.2 51.9 100.4 118.0 65.0 41.5 54.5 53.2 35.9 35.0 137.7 59.2 66.6 53.3 58.9 16.5 6.1 77.3 56.2 38.0 80.4 37.6 36.0 57.6 89.9 42.5 37.6 57.2 30.5 71.4 30.0 19.6 100.5 37.9 59.2 45.0 68.2 13.2 30.0 47.4 19.1 51.6 30.2 85.9 43.5 26.7 29.5 15.5 0.6 15.0 29.7 47.6 44.8 14.7 84.6 9.4 103.3 28.7 6.8 17.2 197.5 163.7 4.8 13.8 62.5 80.9 41.1 22.5 132.4 41.3 16.3 5.0 49.6 9.9 191.1 13.9 13.8 18.7 51.9 53.0 24.6 10.3 79.0 35.0 18.6 4.3 18.4 67.3 105.4 41.9 22.0 81.9 31.3 31.1 15.8 44.6 33.2 22.9 26.2 11.4 1.0 48.2 14.8 12.1 152.9 313.3 824.9 69.8 315.4 94.5 7.8 65.0 59.3 75.9 2.4 76.5 55.1 1668.9 44.7 355.8 10.7 73.8 219.1 51.0 48.9 47.9 58.7 44.2 51.9 54.5 53.2 53.3 57.6 57.2 59.2 15.7 28.9 41.6 6.5 24.3 114.6 75.8 273.0 130.3 1.8 117.8 96.6 31.6 62.9 80.7 40.5 0.0 128.3 45.8 19.4 129.1 95.2 3.9 22.9 20.9 46.9 18.0 3.0 3.4 101.7 78.3 64.9 20.9 24.5 47.0 13.8 23.6 48.5 539.9 1.7 3.9 21.3 111.9 176.9 741.7 21.1 42.0 278.1 147.7 18.7 214.9 76.1 33.0 3.0 1.7 68.7 23.7 72.6 32.5 60.3 75.5 240.6 18.8 3.8 13.1 45.7 53.3 0.9 11.4 36.3 135.7 73.3 54.7 4.5 19.7 76.9 NIPSNAP1 ENSG00000184117 "Nipsnap homolog 1" Q9BPW8 22 29554808-29581327 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 291.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 116.7;Proximal tubular cells: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059227 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA059227: AB_2683951" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (2.15e-2)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.20e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.78e-1)" "prognostic favorable (8.82e-6)" "unprognostic (2.81e-2)" "unprognostic (8.69e-2)" "unprognostic (9.03e-2)" "unprognostic (1.72e-1)" 10.7 43.9 35.4 17.5 37.8 15.5 31.5 31.8 38.5 21.5 33.4 37.4 67.0 19.4 24.9 25.8 26.8 19.8 21.8 37.6 41.7 117.8 291.8 17.8 23.3 37.1 36.5 32.3 24.4 68.0 36.5 17.3 39.3 23.9 38.5 46.2 26.0 27.2 4.4 20.6 49.2 17.8 30.7 19.1 29.3 11.9 36.7 36.7 32.9 5.4 28.3 20.1 18.3 31.7 69.1 81.1 165.3 206.9 29.2 59.4 30.7 39.5 70.7 53.2 68.7 55.5 90.6 48.8 76.8 56.9 56.0 68.2 87.7 100.7 65.1 98.8 90.5 16.8 37.0 173.5 44.1 36.5 23.0 59.5 50.8 44.1 55.0 129.0 73.4 105.3 31.8 78.9 49.2 156.4 59.3 50.1 140.0 106.2 67.5 115.9 51.7 142.6 128.3 59.1 203.9 179.5 46.1 83.2 92.1 79.5 137.1 57.7 34.7 23.2 79.6 28.6 31.9 106.4 56.5 45.6 62.1 57.3 39.4 10.8 9.4 15.9 34.2 17.4 41.2 29.0 34.4 36.2 21.6 27.3 32.6 39.5 13.8 39.5 10.7 11.0 44.9 22.1 35.4 37.8 31.8 38.5 37.6 41.7 37.1 36.5 39.3 30.7 36.7 31.7 7.4 25.6 15.7 6.8 16.3 4.8 12.6 15.8 18.8 22.6 25.5 18.5 22.9 28.6 18.6 42.3 10.4 44.4 9.2 14.4 68.4 45.8 2.1 6.2 13.7 10.1 41.9 24.6 16.9 18.5 14.6 14.2 25.5 12.0 26.0 33.5 11.7 116.7 14.4 10.1 19.9 31.5 26.4 8.7 4.3 6.1 11.1 8.1 5.4 3.7 21.3 38.7 28.8 6.6 10.3 17.8 20.2 14.3 7.3 6.8 35.2 134.7 9.8 24.4 13.1 7.2 12.3 1.4 8.3 20.5 8.1 14.8 20.5 48.1 47.4 8.8 NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Group enriched" "Detected in many" 4 "dendritic cells: 3163.4;NK-cells: 7721.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 5 "NB-4: 180.8;THP-1: 54.5;U-937: 46.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" 12.5 7.9 3.7 23.2 3.6 602.6 7.7 3.6 6.3 5.9 4.2 9.5 11.0 12.5 6.1 7.2 7.9 21.4 6.7 3.5 3.6 6.5 23.5 49.2 136.4 4.9 3.9 4.2 2.2 2.2 3.2 7.9 4.2 4.9 7.3 0.4 9.6 4.5 6.5 2.7 14.6 7.7 4.1 154.6 10.6 3.3 4.3 9.4 6.6 3.3 21.9 16.7 4.4 4.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.9 7.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.6 0.6 2.0 0.8 0.2 0.0 20.1 3.6 0.0 0.0 0.3 0.0 0.2 0.0 2.5 0.5 0.8 0.0 0.0 2.4 180.8 0.0 0.2 0.3 4.4 9.4 0.4 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.3 0.0 54.5 0.4 0.1 0.2 0.6 0.1 2.6 0.9 0.9 0.1 46.6 0.0 76.9 34.1 15.2 6827.0 131.7 2871.2 37.9 811.1 4295.0 87.1 15.4 261.0 3114.2 111.7 4796.8 104.8 67.1 17.5 4929.2 3.7 3.6 3.6 6.3 3.5 3.6 4.9 3.9 4.2 4.1 4.3 4.2 17.2 3.2 8.0 0.0 24.5 5.0 0.1 0.0 0.0 0.0 5.7 3.7 0.7 28.6 1.3 5.5 0.0 1.0 3163.4 1.9 3.9 1.0 0.2 2.7 3.6 7.1 0.0 186.5 0.0 0.0 0.8 5.2 17.3 4.2 24.1 0.2 55.3 9.9 15.0 0.0 0.0 0.5 0.0 132.9 10.2 0.3 0.0 55.5 17.8 1.0 49.4 0.0 7721.0 0.0 0.2 0.0 1.2 0.0 120.4 0.0 0.6 9.2 0.7 0.0 0.0 6.4 4.7 0.0 0.5 1.1 6.5 1.1 1321.5 0.0 1.1 0.1 NKPD1 FLJ33600 ENSG00000179846 "NTPase KAP family P-loop domain containing 1" Q17RQ9 19 45149750-45160815 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 15.9" "Cell type enhanced" "Detected in some" "Horizontal cells: 5.0;Spermatocytes: 2.4;Suprabasal keratinocytes: 1.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 1.4;SiHa: 1.2;U-266/70: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA043339 Uncertain NA NA "Cluster 61: Skin - Cornification" "Cluster 29: U-266 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA043339: AB_10962493" "unprognostic (3.98e-2)" "unprognostic (5.94e-2)" "unprognostic (2.14e-1)" "unprognostic (8.30e-4)" "unprognostic (2.23e-1)" "unprognostic (4.60e-2)" "unprognostic (2.41e-3)" "unprognostic (2.01e-2)" "unprognostic (2.60e-1)" "unprognostic (2.35e-2)" "unprognostic (7.73e-4)" "unprognostic (1.30e-1)" "unprognostic (2.77e-5)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" 0.1 0.1 0.4 0.0 0.1 0.2 0.5 0.2 0.4 1.3 0.0 0.0 0.0 0.1 0.2 1.0 0.3 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.5 0.0 0.5 0.8 0.0 0.3 0.5 0.5 0.1 15.9 0.1 0.0 0.0 0.2 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.2 3.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.3 0.2 0.1 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 1.2 0.7 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.4 0.1 0.2 0.4 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.4 0.0 0.6 0.9 0.2 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.1 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.7 0.0 0.2 0.0 0.0 0.1 5.0 0.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.2 0.5 1.3 0.1 0.0 0.2 0.0 0.1 NKRF "ITBA4, NRF" ENSG00000186416 "NFKB repressing factor" O15226 X 119588337-119606443 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001476 Supported Nucleoplasm,Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" Nucleoli Nucleoplasm "HPA001476: AB_1079488" "unprognostic (6.12e-3)" "unprognostic (7.58e-2)" "unprognostic (8.10e-2)" "unprognostic (2.39e-1)" "unprognostic (9.92e-2)" "unprognostic (4.74e-3)" "prognostic unfavorable (4.92e-5)" "unprognostic (2.47e-1)" "unprognostic (1.20e-1)" "unprognostic (2.65e-1)" "unprognostic (1.33e-2)" "unprognostic (9.56e-3)" "unprognostic (2.62e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-2)" "unprognostic (2.20e-3)" "unprognostic (3.08e-3)" 4.4 6.5 11.3 5.7 11.8 6.9 5.4 9.6 16.9 4.2 7.3 3.7 4.1 3.9 4.0 5.6 4.4 3.5 4.1 11.5 13.1 6.1 6.0 4.1 8.7 11.2 10.1 6.1 3.8 5.2 5.5 6.5 11.5 4.1 3.5 5.3 4.0 3.5 5.5 6.2 4.3 4.0 9.4 5.9 4.1 1.9 11.4 9.5 4.6 4.6 8.4 6.3 4.3 10.6 17.9 18.3 10.4 11.3 8.7 8.5 15.5 10.7 8.5 14.1 15.0 19.8 15.3 31.8 18.4 9.2 12.1 20.4 43.8 16.4 17.2 16.4 28.9 16.8 20.3 12.9 8.3 33.5 11.8 9.5 13.2 16.3 19.2 9.6 14.1 15.3 18.5 12.6 12.5 27.6 20.8 25.2 23.1 26.2 19.9 16.5 15.2 32.7 18.8 12.7 16.7 14.2 15.2 23.1 16.5 10.6 9.7 20.0 12.2 8.7 9.5 19.3 27.1 10.5 14.1 32.9 9.3 36.3 10.1 1.1 0.5 0.7 1.0 0.8 1.1 1.3 1.2 1.3 0.6 1.2 1.9 1.6 0.1 0.5 0.3 0.9 1.8 0.8 11.3 11.8 9.6 16.9 11.5 13.1 11.2 10.1 11.5 9.4 11.4 10.6 5.4 6.4 8.9 5.9 11.1 19.4 10.4 4.1 6.8 13.3 6.1 6.9 4.5 8.6 3.1 5.5 27.1 14.4 8.5 3.0 1.9 4.2 0.1 6.1 7.4 7.0 10.7 2.5 20.6 3.6 14.3 6.1 3.1 8.1 14.7 6.6 3.3 3.9 6.4 8.4 20.6 4.4 10.2 7.5 33.1 0.6 7.8 11.6 5.4 7.5 5.6 4.4 1.0 9.0 9.2 4.1 1.9 6.8 5.2 10.7 3.6 4.4 3.9 7.9 0.0 10.1 7.2 1.7 1.9 6.9 25.7 14.9 15.7 6.9 7.4 9.5 NLRP10 "CLR11.1, NALP10, NOD8, PAN5, Pynod" ENSG00000182261 "NLR family pyrin domain containing 10" Q86W26 11 7957537-7965426 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skin 1: 6.3" "Cell type enriched" "Detected in single" 5 "Microglial cells: 1.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 22.3;BJ: 5.9;HBF TERT88: 7.7;LHCN-M2: 3.7" "Region enhanced" "Detected in some" "olfactory bulb: 2.1" "HPA039498, HPA040101" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" Nucleoplasm "Nuclear membrane" "HPA039498: AB_10795679, HPA040101: AB_10795519" "unprognostic (4.06e-1)" "unprognostic (4.34e-1)" "unprognostic (9.78e-3)" "unprognostic (2.87e-2)" 0.0 0.0 0.1 0.0 0.0 0.1 1.4 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.3 0.0 0.0 0.1 0.0 0.3 0.1 5.9 2.8 1.3 2.8 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 1.0 7.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.9 2.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 NMNAT3 PNAT3 ENSG00000163864 "Nicotinamide nucleotide adenylyltransferase 3" Q96T66 3 139560180-139678017 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 567.3;Alveolar cells type 2: 566.9;Club cells: 217.6;granulocytes: 278.8;Late spermatids: 223.3;Respiratory ciliated cells: 250.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039077, HPA057402" Approved Supported Mitochondria NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA039077: AB_2676336, HPA057402: AB_2683427" "unprognostic (9.45e-3)" "prognostic favorable (9.67e-4)" "unprognostic (2.29e-1)" "unprognostic (1.56e-3)" "unprognostic (2.33e-2)" "unprognostic (2.33e-1)" "unprognostic (2.77e-3)" "unprognostic (6.22e-2)" "unprognostic (9.69e-2)" "unprognostic (1.92e-1)" "prognostic favorable (7.29e-5)" "unprognostic (4.57e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.13e-2)" "unprognostic (1.63e-1)" "unprognostic (1.44e-1)" "unprognostic (3.07e-1)" 7.5 7.4 17.7 4.9 26.7 19.3 8.3 46.5 45.4 6.7 8.2 6.9 9.2 9.4 8.1 5.4 13.6 5.4 11.6 21.5 10.9 9.2 6.6 4.3 4.8 8.6 5.3 20.1 12.0 8.9 5.5 2.2 15.1 6.5 7.5 30.6 9.3 5.5 29.6 19.0 7.8 5.6 2.5 5.4 5.6 11.3 14.6 3.0 7.6 20.3 5.3 5.5 6.8 50.1 9.2 3.6 4.0 4.6 0.9 0.9 5.0 3.7 0.4 0.6 0.5 5.1 6.4 5.9 10.8 0.7 4.3 4.5 3.0 1.2 0.7 5.8 5.3 31.4 9.1 6.9 2.4 5.6 5.5 1.4 7.8 1.0 1.7 9.3 0.5 3.6 5.0 13.1 0.6 6.2 5.3 4.6 9.0 16.5 3.7 4.4 4.5 4.3 1.2 6.3 9.2 5.4 9.2 4.8 3.3 7.3 12.6 15.6 5.6 5.7 12.6 7.2 5.5 23.1 11.0 4.2 3.8 9.0 5.4 11.4 3.6 2.2 2.8 3.4 1.9 2.7 2.4 2.4 2.8 4.5 3.4 3.6 7.0 4.0 3.4 2.9 1.6 1.7 17.7 26.7 46.5 45.4 21.5 10.9 8.6 5.3 15.1 2.5 14.6 50.1 5.5 567.3 566.9 34.9 1.9 4.1 6.3 6.6 6.2 2.7 8.2 7.1 9.7 8.6 217.6 9.2 4.2 0.4 0.8 2.3 11.7 3.3 128.2 2.1 2.4 38.8 6.7 27.1 37.2 3.1 0.2 38.3 3.1 1.7 278.8 9.7 2.5 2.7 2.0 1.7 26.0 6.5 8.2 4.1 2.9 223.3 7.8 31.8 7.2 12.2 1.8 12.3 0.0 46.8 16.9 0.8 2.9 6.4 0.7 6.1 3.5 16.1 250.6 18.5 6.6 13.2 3.8 67.1 3.5 4.4 9.7 0.1 21.5 5.9 10.6 4.8 NMU ENSG00000109255 "Neuromedin U" P48645 4 55595229-55636698 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.2;skin 1: 38.5;vagina: 30.7" "Group enriched" "Detected in many" 4 "Squamous epithelial cells: 212.4;Suprabasal keratinocytes: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "MAIT T-cell: 3.6;memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 37 "T-cells: 3.6" "Cell line enhanced" "Detected in many" "Daudi: 90.2;HaCaT: 382.6;K-562: 311.3;Karpas-707: 135.7" "Group enriched" "Detected in some" 8 "hypothalamus: 1.1;pons and medulla: 4.5" "Low region specificity" "Detected in some" HPA025926 Uncertain "Secreted in other tissues" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA025926: AB_1854539" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (5.83e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.19e-2)" "unprognostic (7.12e-2)" "unprognostic (7.29e-3)" "unprognostic (9.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.07e-10)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (2.54e-2)" "unprognostic (5.55e-2)" 0.1 0.3 0.4 0.7 0.5 9.7 1.5 0.6 1.1 12.3 0.0 1.4 0.8 0.1 0.0 100.2 0.2 0.0 0.2 0.3 2.8 0.2 0.0 0.8 0.5 1.1 2.6 0.1 0.1 0.0 2.3 0.8 0.8 0.2 0.8 0.1 14.3 0.2 0.1 38.5 1.4 0.2 3.0 0.1 4.0 2.2 6.8 1.7 2.5 0.0 7.7 0.1 30.7 0.4 41.3 0.3 22.1 5.6 0.0 0.0 0.0 0.0 0.0 2.9 7.8 0.3 61.5 90.2 8.6 0.0 8.5 382.6 46.1 3.3 2.3 5.6 25.1 0.6 36.0 0.0 0.0 0.0 0.3 0.0 4.2 0.0 3.0 10.0 0.4 6.4 311.3 135.7 0.3 9.9 1.2 0.2 11.7 7.5 11.4 0.2 0.0 0.5 1.9 0.4 19.5 49.0 30.9 0.8 0.1 4.2 20.9 0.1 2.7 0.2 27.5 0.3 54.5 39.1 0.3 0.0 18.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.6 1.1 0.3 2.8 1.1 2.6 0.8 3.0 6.8 0.4 0.0 0.0 2.3 0.0 0.6 16.3 0.6 16.2 4.0 0.2 0.9 1.3 0.1 0.0 8.0 0.0 0.0 2.0 0.0 0.6 0.0 0.1 0.4 3.9 0.3 0.7 0.0 14.5 0.2 0.2 0.1 4.4 29.6 5.8 1.3 0.9 0.0 0.1 0.3 0.0 17.2 0.8 20.3 0.0 1.6 0.3 0.0 0.2 3.6 0.0 0.1 2.0 0.0 1.0 0.2 2.4 0.2 0.0 1.2 0.4 0.0 0.0 7.0 0.0 0.0 0.0 1.2 5.8 10.0 212.4 73.6 0.1 0.7 0.2 2.6 12.0 NNMT ENSG00000166741 "Nicotinamide N-methyltransferase" P40261 11 114257787-114313536 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 388.9" "Group enriched" "Detected in many" 6 "Hepatocytes: 3913.2;Skeletal myocytes: 1639.1" "Cancer enhanced" "Detected in all" "renal cancer: 204.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 255.3;LHCN-M2: 144.1;RPTEC TERT1: 479.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA059180 Approved Approved "Golgi apparatus,Cytosol" NA NA 410000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" Cytosol "HPA059180: AB_2683940" "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" "unprognostic (1.61e-2)" "unprognostic (6.14e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (2.07e-4)" "unprognostic (1.76e-1)" "unprognostic (5.84e-2)" "unprognostic (2.71e-2)" "unprognostic (2.48e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-6)" "prognostic unfavorable (1.75e-4)" "unprognostic (1.11e-1)" "unprognostic (3.37e-3)" "unprognostic (2.77e-2)" 130.9 11.4 1.0 25.2 1.1 0.9 91.9 1.4 1.5 36.0 1.9 37.1 1.5 31.0 2.8 15.4 55.0 43.1 35.5 1.3 1.4 24.1 388.9 64.6 9.6 3.9 1.6 21.3 11.4 1.6 10.6 23.8 2.2 31.9 8.7 0.3 21.1 3.1 73.1 49.3 32.2 30.1 1.7 36.7 30.1 2.2 1.2 2.7 33.0 5.3 8.8 48.6 33.9 3.1 0.2 17.6 0.3 18.6 92.0 118.3 0.1 21.2 58.7 35.2 69.2 0.0 17.5 0.2 58.1 45.1 4.2 0.2 0.0 8.0 34.1 0.2 0.0 0.2 16.7 0.0 123.3 0.2 0.0 255.3 89.4 24.1 37.3 29.8 50.1 0.1 0.3 0.2 144.1 0.1 0.1 0.2 0.1 0.0 0.5 0.2 79.0 0.0 479.6 0.1 0.2 0.2 97.7 0.1 0.3 5.3 0.0 0.2 37.4 18.3 34.3 23.8 3.1 0.3 0.3 0.4 6.4 0.3 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 1.1 1.4 1.5 1.3 1.4 3.9 1.6 2.2 1.7 1.2 3.1 411.8 44.8 411.3 1.0 11.2 103.6 13.2 16.5 2.2 1.9 38.5 73.9 4.7 75.8 13.3 80.9 0.0 1.0 1.6 0.0 9.8 238.3 0.3 19.0 89.9 190.0 5.3 147.2 1.3 157.0 2.5 452.2 5.1 80.5 13.9 0.5 195.2 3913.2 28.4 0.0 1.6 0.0 0.0 126.8 142.1 1.6 74.3 9.2 96.0 1.9 5.7 0.0 0.0 0.0 0.2 323.1 0.0 13.2 1.5 10.8 0.0 99.2 11.9 0.2 0.0 1639.1 154.3 0.3 0.8 1.9 92.1 2.2 20.1 0.0 0.0 3.1 NOD2 "BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, PSORAS1" ENSG00000167207 "Nucleotide binding oligomerization domain containing 2" Q9HC29 16 50693588-50734041 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.6;esophagus: 11.7;skin 1: 14.4;vagina: 12.3" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 8.3;Kupffer cells: 9.0;Langerhans cells: 22.5;Macrophages: 15.2;monocytes: 15.6;Suprabasal keratinocytes: 15.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 23.0;eosinophil: 6.0;intermediate monocyte: 13.1;myeloid DC: 21.3;neutrophil: 10.5;non-classical monocyte: 9.0" "Group enriched" "Detected in many" 5 "dendritic cells: 21.3;granulocytes: 10.5;monocytes: 23.0" "Cell line enhanced" "Detected in some" "HMC-1: 11.6;T-47d: 5.8;THP-1: 7.3;U-266/70: 15.9;U-266/84: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041985, HPA054494" Enhanced Approved "Golgi apparatus,Cytosol" No NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Cytosol" "HPA041985: AB_2677780, HPA054494: AB_2682505" "unprognostic (1.01e-1)" "unprognostic (4.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-3)" "unprognostic (9.91e-3)" "unprognostic (5.84e-2)" "unprognostic (5.90e-3)" "unprognostic (1.23e-1)" "unprognostic (4.17e-1)" "unprognostic (3.88e-2)" "unprognostic (6.94e-3)" "unprognostic (1.48e-2)" "unprognostic (2.31e-9)" "unprognostic (4.38e-2)" "unprognostic (1.08e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-1)" 1.5 0.5 0.5 5.9 0.2 13.6 1.5 0.2 1.0 5.6 0.7 0.9 1.5 0.6 0.3 11.7 0.9 1.3 0.7 0.2 0.4 0.6 1.7 4.3 2.7 1.0 0.9 0.4 0.3 0.2 0.4 1.2 0.7 0.9 0.9 0.0 4.3 0.4 0.6 14.4 1.3 1.8 0.7 4.4 1.4 0.5 1.4 0.8 0.4 0.3 2.3 1.6 12.3 0.8 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 11.6 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.1 0.0 1.5 0.0 0.0 5.8 7.3 0.0 0.0 0.0 0.0 0.0 15.9 7.2 0.0 0.3 0.1 0.0 3.0 23.0 6.0 0.4 13.1 0.7 0.1 1.3 1.4 21.3 0.0 0.1 0.5 10.5 3.4 9.0 1.0 0.9 11.1 0.5 0.2 0.2 1.0 0.2 0.4 1.0 0.9 0.7 0.7 1.4 0.8 0.2 0.0 3.7 0.0 1.9 5.9 0.3 1.2 0.0 0.0 1.4 1.1 0.4 1.5 2.3 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 5.6 0.8 0.6 1.2 0.8 0.1 0.0 0.0 0.4 0.0 8.3 1.3 0.5 0.0 0.5 2.5 0.0 0.1 0.0 2.0 9.0 22.5 0.0 0.0 15.2 1.8 1.9 15.6 0.0 1.0 0.0 0.2 0.0 0.0 0.4 4.3 0.4 0.0 0.1 1.0 0.0 0.0 0.1 0.4 0.1 0.4 6.1 15.5 0.3 2.3 0.1 0.1 0.3 NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.2;breast: 19.8" "Group enriched" "Detected in many" 4 "Adipocytes: 263.8;Endothelial cells: 121.0;Hepatic stellate cells: 188.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 6400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.27e-1)" "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (9.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.88e-2)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.13e-1)" 24.2 4.0 0.0 0.5 0.0 0.0 19.8 0.0 0.0 5.8 0.0 3.6 0.5 7.2 3.2 2.7 5.8 0.0 15.8 0.0 0.0 8.5 2.5 18.5 0.4 0.0 0.1 2.8 2.6 0.0 3.0 1.4 0.0 6.0 0.1 0.0 2.6 0.0 5.6 2.8 3.9 0.0 0.0 2.6 3.9 0.9 0.0 0.0 9.6 0.0 0.1 5.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 263.8 0.0 6.1 0.0 6.0 5.2 32.1 9.9 13.6 2.7 2.6 6.6 8.7 0.0 4.2 5.5 4.2 0.4 11.9 0.6 0.0 2.6 46.0 2.6 3.1 121.0 6.0 12.0 0.2 1.1 0.3 4.7 0.0 1.0 0.0 1.8 188.8 2.3 1.7 6.7 0.2 0.8 4.1 9.3 5.2 35.6 7.2 6.8 3.6 10.3 1.6 21.0 0.0 0.0 0.5 0.4 0.3 5.3 0.7 18.0 1.0 0.9 3.1 3.6 0.0 7.8 9.3 5.5 1.9 1.9 1.6 0.3 3.6 3.7 0.9 5.6 NOX4 "KOX, KOX-1" ENSG00000086991 "NADPH oxidase 4" Q9NPH5 11 89324353-89498187 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 138.0" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 164.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 14.3;HUVEC TERT2: 27.7;TIME: 70.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.91e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-3)" "unprognostic (6.58e-3)" "unprognostic (1.92e-1)" "unprognostic (2.33e-1)" "unprognostic (8.83e-3)" "unprognostic (8.95e-3)" "unprognostic (3.80e-1)" "unprognostic (6.88e-2)" "unprognostic (1.56e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.14e-4)" "unprognostic (1.99e-4)" "unprognostic (9.71e-2)" "unprognostic (5.69e-2)" "unprognostic (3.03e-3)" 7.8 0.7 0.7 0.7 1.2 0.2 3.8 0.7 1.2 1.5 0.0 1.2 0.2 4.9 0.4 0.4 1.3 2.4 7.6 0.4 0.6 138.0 0.3 1.5 0.2 1.0 0.7 0.8 0.3 3.6 0.9 3.1 0.9 1.0 0.3 17.1 3.0 1.3 1.7 1.4 0.6 3.4 0.8 0.4 0.5 0.3 0.7 0.1 2.1 3.5 0.5 1.4 1.1 1.7 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.5 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.1 14.3 27.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 6.1 0.0 0.0 0.3 7.1 0.4 0.0 70.6 0.2 5.0 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 1.2 0.7 1.2 0.4 0.6 1.0 0.7 0.9 0.8 0.7 1.7 4.4 0.0 0.0 2.9 1.0 0.6 0.1 0.4 0.0 7.5 0.2 0.3 1.0 0.0 0.0 11.0 6.2 2.2 0.2 0.1 15.6 0.0 0.8 1.0 1.4 5.9 0.0 0.0 30.0 0.0 0.8 9.2 0.0 3.0 0.0 0.6 2.5 0.1 0.2 0.0 21.1 0.0 0.0 0.0 0.5 0.7 0.3 1.3 0.0 6.5 0.1 4.5 0.0 7.1 28.4 0.1 0.0 1.2 0.3 0.1 0.0 164.0 0.0 27.1 0.0 1.2 1.0 0.6 0.7 0.1 0.3 2.5 1.1 0.1 0.0 0.1 NPAS1 "bHLHe11, MOP5, PASD5" ENSG00000130751 "Neuronal PAS domain protein 1" Q99742 19 47019837-47045775 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;skin 1: 7.7" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 16.7;Gastric mucus-secreting cells: 27.0;Inhibitory neurons: 28.3" "Cancer enhanced" "Detected in many" "testis cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 9.9;Daudi: 10.2;HEK 293: 11.1;HMC-1: 9.0;NB-4: 18.1;U-266/84: 11.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA043364, HPA072259" Approved Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA043364: , HPA072259: AB_2686500" "unprognostic (2.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.32e-4)" "unprognostic (1.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-3)" "unprognostic (2.21e-2)" "unprognostic (1.09e-1)" "unprognostic (3.75e-1)" "unprognostic (5.91e-2)" "unprognostic (2.64e-1)" "unprognostic (2.14e-8)" "unprognostic (8.82e-2)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (4.20e-2)" 0.9 0.4 3.1 0.3 1.8 0.2 0.7 0.3 6.3 0.4 1.9 0.4 0.0 0.1 0.0 1.0 0.6 0.0 1.1 5.4 2.8 1.7 0.6 0.4 0.5 2.9 2.5 0.2 0.6 0.0 1.3 0.1 4.3 0.4 0.0 0.5 0.4 0.0 0.1 7.7 0.4 0.1 0.7 2.8 2.7 0.6 1.5 0.1 0.5 0.0 0.3 0.4 0.7 2.0 0.2 2.4 0.3 0.5 0.2 0.2 0.0 9.9 0.3 0.1 0.4 0.7 0.5 10.2 2.2 8.1 0.4 0.2 2.1 0.2 0.1 0.7 11.1 0.8 1.2 2.5 0.0 5.5 9.0 0.9 0.4 0.0 0.1 0.6 0.2 1.3 3.5 0.8 1.3 0.9 0.4 18.1 2.4 0.4 1.7 0.9 0.4 0.8 0.6 0.6 0.7 0.6 0.8 0.3 2.4 0.8 2.1 1.7 0.1 0.2 0.9 0.1 0.2 5.4 11.5 2.2 1.2 1.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 0.3 6.3 5.4 2.8 2.9 2.5 4.3 0.7 1.5 2.0 0.1 0.0 0.6 1.6 1.1 0.8 1.4 1.1 1.8 0.7 2.2 2.5 1.1 0.0 1.1 0.0 16.7 0.0 0.1 0.3 0.0 0.6 0.1 0.4 0.2 0.2 1.2 2.7 5.7 0.4 0.1 0.5 27.0 0.4 0.0 0.7 0.0 0.1 0.3 0.0 28.3 1.4 2.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 5.4 0.0 2.0 1.2 1.0 0.2 0.0 2.6 1.5 0.0 0.9 2.0 5.4 0.0 0.1 1.1 0.4 2.1 2.2 2.3 0.0 1.2 0.1 0.6 1.2 NPAS4 "bHLHe79, Le-PAS, NXF, PASD10" ENSG00000174576 "Neuronal PAS domain protein 4" Q8IUM7 11 66421004-66426707 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 170.4" "Group enriched" "Detected in some" 4 "Bipolar cells: 10.2;Horizontal cells: 11.8;Rod photoreceptor cells: 5.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 13 "cerebellum: 170.4;cerebral cortex: 55.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 4.9;cerebellum: 5.0;cerebral cortex: 7.5;hippocampal formation: 4.6;olfactory bulb: 3.8" HPA039255 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA039255: AB_10674282" "unprognostic (7.81e-2)" "unprognostic (9.93e-2)" "unprognostic (1.55e-2)" "unprognostic (1.24e-1)" "unprognostic (2.51e-1)" "unprognostic (1.78e-3)" "unprognostic (4.97e-1)" "unprognostic (7.84e-2)" "unprognostic (1.85e-2)" "unprognostic (3.29e-2)" "unprognostic (3.96e-2)" "unprognostic (1.12e-3)" "unprognostic (1.58e-1)" "unprognostic (1.37e-1)" "unprognostic (4.24e-1)" "unprognostic (3.21e-2)" 0.2 0.2 0.8 0.4 2.9 0.0 0.1 170.4 55.3 0.8 0.5 2.7 0.1 3.3 0.1 0.3 1.3 0.1 0.2 4.2 8.6 0.1 0.1 0.1 0.0 2.2 1.6 0.3 0.3 0.0 19.3 0.0 3.6 1.2 0.1 0.1 0.1 0.7 0.0 0.1 0.5 1.3 0.1 0.0 1.1 0.1 1.2 0.0 0.1 0.2 0.0 1.1 0.5 4.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.9 170.4 55.3 4.2 8.6 2.2 1.6 3.6 0.1 1.2 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.2 0.1 0.4 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.8 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NPDC1 "CAB-, CAB1, DKFZp586J0523" ENSG00000107281 "Neural proliferation, differentiation and control 1" Q9NQX5 9 137039463-137046179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 397.0;Endothelial cells: 307.2;Enteroendocrine cells: 281.6;Hepatic stellate cells: 406.2;Intestinal goblet cells: 589.1" "Cancer enhanced" "Detected in all" "prostate cancer: 146.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 12.3;MAIT T-cell: 14.7;memory CD4 T-cell: 19.0;memory CD8 T-cell: 18.9;T-reg: 15.9" "Lineage enriched" "Detected in many" 5 "T-cells: 19.0" "Cell line enhanced" "Detected in many" "MCF7: 138.4;RPMI-8226: 132.8;T-47d: 140.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008189 Approved Approved Nucleoplasm,Cytosol NA NA 240000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Cytosol "HPA008189: AB_1854584" "unprognostic (6.94e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.01e-5)" "prognostic favorable (6.19e-5)" "unprognostic (2.06e-1)" "unprognostic (4.83e-3)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (8.65e-2)" "unprognostic (1.53e-1)" "prognostic favorable (3.18e-4)" "unprognostic (2.40e-1)" "unprognostic (2.65e-2)" "unprognostic (1.23e-2)" "unprognostic (2.35e-1)" "unprognostic (4.20e-2)" "unprognostic (8.84e-2)" 129.5 45.7 140.8 12.2 128.1 3.4 133.0 110.6 181.3 130.5 55.0 93.1 23.4 121.6 4.3 53.7 148.6 24.9 149.1 143.3 143.1 75.9 23.7 115.4 13.0 138.9 142.3 68.2 81.2 23.0 266.0 21.1 131.3 260.5 13.4 9.2 137.4 35.1 34.0 56.4 72.1 16.9 120.7 145.2 126.2 35.3 142.9 2.9 68.4 12.4 3.9 97.9 90.5 114.7 33.6 41.9 10.1 67.1 23.7 23.8 2.8 68.7 23.0 16.9 6.7 17.1 18.5 30.3 50.7 28.6 4.6 122.4 8.6 20.5 1.6 25.0 40.4 13.6 123.7 12.9 33.3 11.9 0.3 16.5 31.9 8.7 17.9 43.1 43.6 13.2 0.7 0.8 3.5 138.4 1.0 1.1 21.1 111.0 68.1 19.9 0.0 132.8 28.6 22.7 77.2 50.0 18.4 65.3 46.5 3.6 140.1 17.9 73.9 12.4 21.6 84.1 21.0 0.1 0.4 1.4 17.7 1.2 10.5 0.0 0.6 0.9 12.3 0.1 14.7 0.1 19.0 18.9 1.1 0.0 0.5 3.1 0.0 0.2 0.1 3.4 15.9 3.3 140.8 128.1 110.6 181.3 143.3 143.1 138.9 142.3 131.3 120.7 142.9 114.7 397.0 0.0 7.7 64.3 3.4 23.6 77.6 15.0 31.3 97.5 174.0 139.7 18.3 71.4 19.8 29.5 16.7 1.1 5.5 122.2 0.0 52.5 1.8 39.0 27.7 307.2 281.6 19.3 71.7 66.0 1.3 61.2 153.9 101.3 0.0 9.2 406.2 1.9 22.2 62.2 64.7 589.1 18.3 21.0 20.0 6.9 161.2 6.6 30.2 37.5 3.0 38.5 1.0 38.2 39.0 33.0 106.0 145.6 1.4 234.9 37.5 0.7 7.5 62.0 39.5 23.9 38.9 2.8 19.0 15.9 23.7 1.8 12.3 9.1 98.1 103.1 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 NPM2 ENSG00000158806 "Nucleophosmin/nucleoplasmin 2" Q86SE8 8 22024125-22036897 "Predicted intracellular proteins" Fertilization "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.0;parathyroid gland: 39.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.4;Cone photoreceptor cells: 20.9;Excitatory neurons: 21.3;Inhibitory neurons: 21.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 10.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 17.7;HEL: 14.5;Hep G2: 32.4;JURKAT: 9.5;THP-1: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041070 Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nucleoli" "HPA041070: AB_2677285" "unprognostic (1.40e-2)" "unprognostic (3.30e-2)" "unprognostic (3.11e-2)" "unprognostic (2.49e-2)" "unprognostic (1.55e-1)" "unprognostic (2.06e-1)" "unprognostic (1.61e-1)" "unprognostic (3.03e-2)" "unprognostic (5.30e-3)" "unprognostic (1.01e-1)" "prognostic favorable (9.02e-4)" "unprognostic (2.23e-1)" "prognostic favorable (3.18e-6)" "unprognostic (8.05e-3)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" "unprognostic (1.30e-1)" 0.6 18.4 11.0 0.1 16.9 1.2 2.1 7.4 40.0 4.9 2.2 1.1 2.2 5.0 0.9 1.0 3.2 1.9 2.3 12.4 9.2 6.6 1.6 1.8 0.6 7.5 7.6 1.5 11.0 39.2 18.5 0.5 10.0 6.6 1.0 5.7 2.7 1.4 0.3 2.2 1.2 3.6 2.3 12.5 1.9 5.1 7.1 2.9 25.3 0.3 0.4 2.0 2.3 13.5 3.9 0.5 0.2 0.2 0.9 0.0 1.5 0.5 0.5 2.4 4.9 1.6 3.6 0.0 1.1 0.0 0.2 17.7 0.5 0.0 1.4 0.1 0.5 14.5 1.0 32.4 3.1 1.9 1.3 0.5 2.3 0.0 0.3 3.7 0.0 9.5 0.5 0.0 0.1 0.0 0.2 3.9 0.7 6.4 0.4 0.3 1.4 0.8 5.6 0.1 3.8 0.2 0.0 0.1 4.6 0.0 0.7 11.2 0.0 0.0 0.3 0.6 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.7 0.0 0.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 11.0 16.9 7.4 40.0 12.4 9.2 7.5 7.6 10.0 2.3 7.1 13.5 0.1 0.0 1.1 1.0 0.7 0.1 9.7 3.7 0.6 29.4 3.1 5.2 2.1 5.7 8.8 0.0 20.9 0.1 0.5 0.6 3.9 9.4 15.1 1.1 0.3 0.6 11.4 0.4 21.3 8.0 0.2 1.7 1.5 1.1 0.0 1.4 2.5 0.5 4.6 6.7 21.9 2.1 2.0 0.0 0.3 14.4 0.6 0.9 10.6 1.9 1.0 0.9 0.0 2.5 1.6 4.3 0.8 0.4 0.6 3.4 0.5 14.6 7.7 4.2 0.0 0.4 1.6 0.5 0.9 1.1 1.1 0.3 2.7 7.6 1.2 5.8 NPR2 "AMDM, ANPb, ANPRB, GUCY2B, NPRB" ENSG00000159899 "Natriuretic peptide receptor 2" P20594 9 35791591-35809732 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis, Osteogenesis" "Lyase, Receptor" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Excitatory neurons: 69.1;Inhibitory neurons: 68.9;Microglial cells: 34.7;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 30.9;ASC TERT1: 21.1;BJ hTERT+: 20.2;HHSteC: 20.1;HSkMC: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.93e-2)" "unprognostic (8.22e-3)" "unprognostic (9.25e-3)" "unprognostic (3.59e-2)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-1)" "unprognostic (2.40e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-1)" "unprognostic (3.99e-2)" "unprognostic (6.99e-3)" "unprognostic (7.10e-2)" "unprognostic (3.24e-1)" "unprognostic (7.86e-2)" 12.4 8.2 9.3 1.7 9.4 0.3 10.3 14.4 9.9 25.7 7.7 15.6 1.8 20.5 8.7 3.2 15.1 3.2 12.8 9.1 11.4 6.7 8.6 9.1 2.3 11.8 9.4 9.4 3.2 1.3 13.8 4.7 11.5 10.9 2.8 4.1 5.3 6.5 10.8 8.3 7.5 9.9 8.2 4.9 7.8 4.8 10.7 2.2 6.0 8.6 1.7 12.1 14.7 7.9 0.0 2.9 2.2 0.0 30.9 21.1 1.9 9.3 20.2 7.0 6.4 4.5 4.3 1.8 3.0 17.9 12.8 1.2 3.6 0.2 6.1 2.2 1.0 1.8 4.3 3.4 20.1 0.4 0.0 23.8 1.8 8.9 0.6 7.6 12.7 2.5 0.7 0.2 13.4 1.0 0.5 0.8 3.5 1.0 3.7 2.4 0.2 0.5 1.8 1.4 1.1 0.7 0.4 0.1 0.6 3.8 0.2 0.0 8.2 8.5 7.8 3.2 1.2 0.5 0.6 4.8 10.4 0.6 5.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 9.3 9.4 14.4 9.9 9.1 11.4 11.8 9.4 11.5 8.2 10.7 7.9 2.7 3.2 3.4 35.6 0.0 1.1 0.6 0.6 1.2 5.1 0.7 1.4 0.7 1.5 0.3 0.0 2.1 0.4 0.5 0.7 0.0 0.6 0.3 1.4 9.2 4.4 0.0 0.0 69.1 0.8 0.2 7.2 0.5 2.0 1.3 9.6 6.1 4.5 0.4 3.3 68.9 0.7 0.0 0.3 2.1 0.3 9.3 0.3 0.0 34.7 0.0 6.8 0.0 51.8 16.3 0.6 3.6 7.9 0.2 2.7 0.2 0.6 1.1 2.2 0.0 5.1 3.4 4.5 3.1 0.1 1.6 0.3 0.7 0.8 1.1 0.4 NPY1R NPYR ENSG00000164128 "Neuropeptide Y receptor Y1" P25929 4 163323962-163344832 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 119.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 32.8;Excitatory neurons: 39.8;Hepatic stellate cells: 160.6;Sertoli cells: 46.0;Smooth muscle cells: 34.1" "Cancer enriched" "Detected in many" 13 "breast cancer: 65.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "HEL: 128.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "prognostic favorable (7.68e-5)" "unprognostic (9.14e-3)" "unprognostic (1.55e-1)" "unprognostic (5.09e-2)" "unprognostic (2.60e-1)" "unprognostic (9.29e-2)" "unprognostic (5.28e-3)" "unprognostic (2.26e-1)" "unprognostic (4.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.89e-2)" "unprognostic (5.92e-2)" "unprognostic (7.39e-2)" "unprognostic (1.92e-3)" "unprognostic (5.48e-2)" "unprognostic (1.74e-1)" "unprognostic (2.21e-1)" 30.5 31.0 10.4 2.9 13.1 0.0 32.4 0.0 13.7 7.8 0.0 5.8 1.0 7.3 10.2 1.8 8.4 4.5 4.8 9.1 19.7 32.3 14.7 2.1 17.3 0.3 0.8 2.8 28.7 3.6 3.0 5.2 0.4 2.5 4.5 4.4 21.4 8.3 2.9 9.8 1.5 5.7 5.7 119.6 1.8 4.1 2.2 1.1 7.9 2.6 0.9 1.8 4.9 9.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.0 0.0 7.0 0.0 0.0 0.0 0.0 128.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 1.2 0.0 4.6 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.1 0.0 0.0 0.4 3.0 0.0 0.0 0.1 1.2 0.0 0.6 0.1 0.0 0.0 1.4 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 10.4 13.1 0.0 13.7 9.1 19.7 0.3 0.8 0.4 5.7 2.2 9.0 2.1 0.0 0.5 1.3 0.7 2.8 0.7 0.0 3.4 11.6 19.2 3.3 0.9 1.5 0.0 0.0 2.1 0.0 0.0 3.4 13.7 12.5 5.0 0.0 0.4 10.8 32.8 0.0 39.8 0.0 0.0 5.1 0.0 0.1 0.0 3.7 160.6 0.9 0.1 0.0 18.8 1.6 0.0 7.2 0.9 2.4 11.5 0.1 5.4 4.7 0.0 1.1 0.0 2.0 1.4 0.1 15.9 0.4 0.0 0.5 0.1 0.1 0.0 2.1 46.0 1.1 34.1 0.5 0.6 0.1 1.7 0.0 0.6 0.5 2.1 0.3 NPY5R NPYR5 ENSG00000164129 "Neuropeptide Y receptor Y5" Q15761 4 163343892-163351934 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 7.2;lymphoid tissue: 8.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.6;Granulosa cells: 1.4;Inhibitory neurons: 3.5;Smooth muscle cells: 3.1;Spermatocytes: 3.0" "Cancer enhanced" "Detected in single" "breast cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.63e-6)" "unprognostic (3.00e-1)" "unprognostic (2.79e-1)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "unprognostic (3.74e-2)" "unprognostic (3.94e-2)" "unprognostic (5.40e-2)" "unprognostic (4.30e-2)" "unprognostic (3.99e-2)" "unprognostic (1.76e-1)" "unprognostic (3.94e-1)" 7.2 3.3 0.9 0.3 2.2 0.0 1.7 0.0 1.5 0.7 0.0 0.3 0.0 0.7 1.0 0.2 0.8 0.5 0.7 1.1 2.8 4.6 1.0 0.3 2.4 0.2 0.4 0.2 1.0 0.7 0.3 2.9 0.2 0.2 0.3 0.2 3.7 0.9 0.1 0.8 0.1 0.7 1.1 8.8 0.2 5.1 0.8 0.1 0.7 0.4 0.1 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.2 0.0 1.5 1.1 2.8 0.2 0.4 0.2 1.1 0.8 0.6 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.0 0.0 0.5 0.0 0.0 4.6 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.1 3.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 NR1D1 "ear-1, hRev, Rev-ErbAalpha, REVERBA, REVERBalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092793-40100589 "Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 325.5" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 95.5;Suprabasal keratinocytes: 81.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.5" "Group enriched" "Detected in many" 6 "monocytes: 5.5;T-cells: 18.5" "Cell line enhanced" "Detected in all" "Karpas-707: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies" "HPA007935: AB_10601277" "unprognostic (1.38e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.53e-1)" "unprognostic (2.24e-2)" "unprognostic (1.05e-1)" "unprognostic (4.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.93e-3)" "unprognostic (9.93e-3)" "unprognostic (2.73e-1)" "unprognostic (9.15e-3)" "unprognostic (4.54e-3)" "unprognostic (2.49e-1)" "unprognostic (3.09e-1)" "unprognostic (1.34e-1)" 72.3 53.7 23.5 6.3 27.0 5.4 63.1 52.9 49.7 109.6 10.6 53.3 14.3 35.8 4.5 42.5 27.7 7.1 60.8 24.9 17.2 38.0 43.2 49.2 9.3 18.1 20.9 71.3 24.3 9.0 32.0 6.0 15.9 40.5 4.0 50.4 52.9 16.3 99.0 325.5 23.0 7.5 12.9 11.6 31.5 12.5 34.0 6.3 32.1 38.1 5.4 42.5 96.5 25.2 5.5 7.8 1.6 6.2 9.0 6.2 2.2 11.9 19.5 3.9 4.9 5.1 19.5 6.7 6.9 13.8 12.9 15.4 4.1 18.0 2.9 5.6 4.1 4.8 7.9 13.5 14.6 7.2 6.9 13.5 12.8 13.3 28.2 12.6 4.9 7.7 7.2 60.6 3.8 3.8 10.7 6.1 3.0 10.8 12.3 7.5 2.2 20.7 5.4 4.9 5.1 2.9 7.6 9.7 12.4 2.7 4.6 5.8 4.7 17.2 16.7 14.1 9.5 21.5 35.7 2.6 23.4 4.0 13.6 0.0 0.5 0.0 4.4 2.0 18.5 1.7 5.5 6.4 1.1 2.1 4.8 3.5 0.2 1.0 5.5 1.4 8.0 1.8 23.5 27.0 52.9 49.7 24.9 17.2 18.1 20.9 15.9 12.9 34.0 25.2 16.4 3.2 2.0 17.3 5.7 64.5 47.5 20.5 67.2 71.4 9.4 15.1 5.7 8.6 11.9 1.8 4.2 2.6 4.9 26.0 7.9 16.1 2.3 25.4 30.6 18.6 8.3 3.6 7.1 11.8 1.2 26.5 31.1 64.2 2.5 2.7 6.8 31.8 2.5 42.1 6.2 7.2 8.2 3.4 19.4 1.5 21.8 7.7 19.6 8.4 1.2 39.0 5.2 5.0 1.2 26.0 14.7 38.7 10.5 35.4 58.8 7.9 5.0 29.7 6.6 9.6 19.4 2.0 11.1 95.5 81.1 2.3 11.9 13.7 6.0 28.7 NR2F2 "ARP1, COUP-TFII, COUPTF2, COUPTFB, NF-E3, SVP40, TFCOUP2" ENSG00000185551 "Nuclear receptor subfamily 2 group F member 2" P24468 15 96325938-96340263 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 292.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 542.2;Hepatic stellate cells: 395.5;Leydig cells: 510.4;Peritubular cells: 610.5;Sertoli cells: 486.4;Smooth muscle cells: 385.7;Theca cells: 572.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058974 Approved Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA058974: AB_2732629" "unprognostic (9.28e-2)" "unprognostic (2.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.42e-2)" "unprognostic (8.96e-2)" "unprognostic (5.44e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (2.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.89e-1)" "unprognostic (9.19e-2)" "unprognostic (5.14e-2)" "unprognostic (5.96e-2)" "unprognostic (1.72e-2)" "unprognostic (7.47e-2)" "unprognostic (1.28e-2)" 95.5 43.1 32.7 18.8 19.2 0.1 59.7 15.0 19.6 128.6 23.5 52.6 21.5 120.9 61.8 22.1 101.5 65.7 44.4 20.0 24.8 79.8 32.1 56.8 42.4 16.2 21.9 292.4 20.0 30.7 20.3 74.7 18.2 60.6 26.7 2.5 22.9 126.4 33.1 24.1 32.1 81.8 12.5 106.2 82.3 26.7 49.3 7.8 46.2 31.5 15.1 46.3 74.5 10.7 154.7 39.1 125.6 78.5 249.1 85.5 41.9 109.1 83.2 111.1 94.3 134.8 153.4 0.1 86.8 55.2 44.1 90.4 22.3 78.3 138.8 0.5 86.5 49.9 48.7 24.6 69.5 38.7 18.0 61.3 26.5 92.5 19.8 130.5 207.3 0.1 135.3 0.4 71.2 105.5 0.1 27.6 1.2 59.6 52.7 0.1 30.9 0.2 244.7 165.7 15.8 0.2 12.3 3.7 17.5 55.0 61.1 2.8 215.3 119.9 39.7 28.3 38.8 0.1 0.4 0.4 67.0 18.9 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 19.2 15.0 19.6 20.0 24.8 16.2 21.9 18.2 12.5 49.3 10.7 133.4 28.9 18.1 0.7 1.1 14.4 24.9 71.7 39.3 7.5 51.9 50.8 46.4 203.0 34.6 62.5 25.0 126.2 2.0 35.7 46.9 22.0 3.2 70.9 542.2 166.1 26.4 5.3 0.1 10.9 50.3 125.8 80.0 68.9 0.0 41.5 395.5 51.6 10.3 3.3 24.8 35.5 32.6 12.2 20.1 22.9 510.4 5.0 26.6 36.5 0.6 30.2 0.0 0.0 0.5 15.6 23.9 610.5 2.8 22.3 14.3 65.5 37.3 13.8 486.4 27.8 385.7 6.4 7.9 20.5 10.4 35.3 5.8 572.5 27.1 21.3 NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 17.8;liver: 38.6;pancreas: 61.1" "Cell type enriched" "Detected in many" 5 "Granulosa cells: 276.2" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.2;neutrophil: 1.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "A549: 25.0;CACO-2: 6.2;HAP1: 14.9;HMC-1: 6.4;HUVEC TERT2: 20.4" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Not detected" "Not detected" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA005455: AB_1078140, HPA017067: AB_1844767" "unprognostic (7.47e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (1.19e-2)" "unprognostic (6.63e-3)" "unprognostic (4.46e-2)" "unprognostic (3.78e-2)" "unprognostic (3.34e-1)" "unprognostic (8.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.00e-7)" "unprognostic (5.48e-2)" "unprognostic (5.07e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-1)" 5.4 0.4 0.5 2.6 0.2 0.9 3.7 0.5 0.3 3.4 0.2 11.9 17.4 3.3 1.4 0.9 2.2 8.0 1.0 0.3 2.8 0.7 38.6 2.7 2.1 0.7 0.6 1.0 61.1 0.4 0.1 0.4 0.8 1.6 13.1 0.2 0.5 0.8 1.1 1.1 17.8 4.3 0.4 0.2 1.3 0.8 0.8 0.5 0.9 0.7 1.4 1.8 1.2 0.7 0.0 25.0 0.0 0.1 0.0 0.2 0.6 0.0 0.4 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.7 0.7 14.9 0.0 0.0 3.3 1.1 0.0 0.3 2.7 0.5 0.1 6.4 0.1 0.0 0.0 0.1 0.0 20.4 0.1 0.0 0.3 0.0 0.6 0.0 0.4 0.9 0.0 0.3 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 1.7 4.7 0.3 0.1 1.0 0.2 0.1 0.2 3.4 2.3 2.6 0.3 0.2 0.1 3.2 0.4 0.4 0.2 0.2 0.2 0.3 0.3 0.3 0.1 0.4 0.4 0.3 1.5 0.5 0.2 0.5 0.4 0.1 0.5 0.2 0.5 0.3 0.3 2.8 0.7 0.6 0.8 0.4 0.8 0.7 23.7 0.0 1.7 0.3 0.2 1.9 0.1 0.0 0.0 0.2 0.2 0.0 9.9 32.9 0.0 0.0 0.0 0.0 0.3 37.5 0.0 38.2 0.4 0.3 0.3 32.4 4.9 2.7 0.4 54.5 0.0 0.8 0.0 0.2 13.3 276.2 38.6 38.5 0.1 0.0 0.6 13.8 0.0 4.9 1.5 0.3 0.6 0.6 0.0 0.0 3.1 0.0 0.0 1.0 0.3 22.0 21.8 0.0 1.2 0.3 49.9 0.0 0.8 0.3 0.0 0.5 6.1 0.1 0.1 0.0 1.4 0.0 0.3 0.1 32.3 0.2 NREP "C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17" ENSG00000134986 "Neuronal regeneration related protein" Q16612 5 111662621-111997464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 118.3;Excitatory neurons: 116.1;Theca cells: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "myeloid DC: 24.6;NK-cell: 6.9;plasmacytoid DC: 25.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 425.3;SH-SY5Y: 461.8" "Region enriched" "Detected in all" 5 "cerebellum: 1766.0" "Region enhanced" "Detected in all" "cerebellum: 219.5" HPA000545 Approved Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA000545: AB_1845721" "unprognostic (2.85e-2)" "unprognostic (1.00e-2)" "unprognostic (2.30e-1)" "unprognostic (1.48e-3)" "unprognostic (4.37e-1)" "unprognostic (2.26e-1)" "unprognostic (8.16e-3)" "unprognostic (1.58e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (3.76e-2)" "unprognostic (2.02e-1)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (5.76e-3)" 18.9 56.5 50.1 19.4 52.6 36.7 29.3 141.8 71.6 32.3 56.9 28.6 16.9 84.8 17.9 23.0 18.2 65.4 70.9 52.5 44.0 49.5 50.7 27.7 17.3 47.8 52.1 41.8 9.8 8.4 13.3 119.8 50.8 52.7 25.2 107.4 36.1 72.2 179.9 22.1 16.7 54.6 44.6 36.9 25.7 12.7 46.4 168.1 18.6 118.2 18.4 27.5 16.8 54.7 0.6 7.1 425.3 91.5 20.2 46.6 20.3 140.9 83.9 135.7 221.0 0.8 2.8 73.1 44.6 71.3 18.9 0.3 91.0 5.2 69.4 29.5 13.0 57.5 35.2 77.6 28.1 77.0 0.8 45.6 22.5 129.5 44.5 318.6 154.2 81.4 0.6 7.4 143.4 1.6 308.3 53.7 244.1 0.2 33.3 326.3 173.4 19.9 52.2 1.6 96.9 461.8 31.6 2.2 2.9 224.2 17.7 210.6 31.1 163.7 54.1 80.8 15.8 34.6 29.3 92.3 35.6 159.8 32.8 0.0 4.0 0.0 0.0 2.2 0.0 1.6 0.1 0.2 24.6 1.1 1.2 1.6 0.1 6.9 1.0 25.1 0.0 2.2 50.1 52.6 141.8 71.6 52.5 44.0 47.8 52.1 50.8 44.6 46.4 54.7 20.8 6.4 30.8 43.1 3.6 18.1 1.6 4.5 14.2 66.9 12.4 22.6 33.4 8.6 5.7 12.9 87.6 118.3 12.9 2.5 33.2 14.4 2.5 5.4 69.1 38.9 21.6 52.2 116.1 5.5 18.6 31.7 31.1 7.4 5.1 69.9 27.5 10.1 35.5 20.2 51.4 9.3 42.7 10.0 19.0 1.0 8.4 14.9 14.2 17.8 11.5 14.9 5.2 37.2 4.6 8.2 2.0 23.3 0.9 0.7 1.2 61.0 0.5 29.0 13.1 25.4 51.8 0.8 12.6 11.9 12.6 31.5 3.2 150.8 11.3 0.2 NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3;retina: 5.2" "Group enriched" "Detected in some" 18 "Astrocytes: 2921.6;Excitatory neurons: 3761.0;Inhibitory neurons: 3088.3;Oligodendrocyte precursor cells: 1175.2" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SK-MEL-30: 2.7;U-2 OS: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" 0.1 0.4 16.4 0.3 11.4 0.0 1.3 0.0 17.3 0.1 0.0 0.4 0.1 0.0 0.0 0.1 4.7 2.8 0.4 16.1 2.6 0.7 0.5 0.7 0.1 1.2 6.3 0.0 0.1 0.1 2.0 0.3 0.4 0.1 0.1 5.2 2.6 0.2 0.0 0.6 0.1 0.1 2.5 0.1 0.3 1.8 9.9 0.0 0.2 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 11.4 0.0 17.3 16.1 2.6 1.2 6.3 0.4 2.5 9.9 3.5 0.1 0.0 0.0 2921.6 0.1 0.0 0.0 0.0 0.0 15.9 0.7 0.6 0.8 2.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.9 31.4 0.0 0.0 0.7 0.0 0.0 3761.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3088.3 0.0 0.0 0.0 0.0 12.8 0.6 0.1 0.0 148.0 0.0 6.7 0.0 1175.2 50.2 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 NSDHL "H105e3, SDR31E1, XAP104" ENSG00000147383 "NAD(P) dependent steroid dehydrogenase-like" Q15738 X 152830967-152869729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant, Ichthyosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 53.0;Hepatocytes: 55.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000248, HPA000571" Enhanced Enhanced "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "Lipid droplets" "HPA000248: AB_1079507, HPA000571: AB_1079506" "unprognostic (1.84e-1)" "prognostic favorable (5.65e-4)" "unprognostic (2.66e-1)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.03e-1)" "unprognostic (5.70e-2)" "unprognostic (4.32e-2)" "unprognostic (5.62e-2)" "unprognostic (2.63e-1)" "prognostic favorable (6.09e-5)" "unprognostic (3.53e-2)" "unprognostic (1.36e-1)" "unprognostic (3.91e-2)" "unprognostic (4.79e-2)" 24.0 38.8 13.2 10.2 12.6 8.9 20.2 14.2 13.3 20.3 13.7 13.9 17.6 13.6 44.5 51.7 14.9 7.9 22.4 13.7 14.3 14.9 50.4 12.9 9.1 16.8 15.4 10.3 10.6 12.9 8.8 10.3 18.5 14.8 13.5 10.4 16.7 21.3 10.1 22.6 24.2 12.5 13.4 9.5 13.8 8.9 15.2 9.9 13.3 10.9 18.1 12.1 24.1 15.1 135.6 48.9 65.5 33.8 54.9 41.5 36.2 26.3 35.2 46.9 59.3 68.5 71.7 67.0 86.0 35.9 174.2 67.6 85.5 122.1 41.3 22.0 49.5 27.9 44.7 70.3 39.8 27.6 21.1 51.1 46.3 92.2 23.0 20.2 44.2 28.7 46.4 29.1 36.1 60.1 27.3 35.8 26.0 67.4 58.1 19.9 47.4 54.6 98.9 55.7 23.4 26.5 23.4 34.6 28.4 44.9 23.1 35.0 38.7 21.6 35.4 52.3 51.0 40.9 29.4 114.9 40.0 42.4 20.8 21.0 19.6 18.7 16.3 18.7 16.4 19.1 16.1 14.1 19.4 15.1 11.6 12.7 2.2 19.7 14.2 17.4 20.4 15.2 13.2 12.6 14.2 13.3 13.7 14.3 16.8 15.4 18.5 13.4 15.2 15.1 7.1 12.8 16.7 5.9 6.3 10.8 12.8 53.0 10.8 4.3 11.7 6.1 25.0 15.7 29.0 12.9 0.0 21.5 6.1 9.6 9.8 20.1 13.3 15.5 6.6 9.2 6.0 13.0 2.2 20.3 22.0 9.0 8.2 15.5 8.2 14.0 7.5 55.0 18.6 1.7 2.2 10.2 26.4 8.7 9.6 8.0 8.4 7.9 5.4 1.0 11.0 10.6 7.2 2.5 5.7 21.4 11.9 9.1 11.3 10.4 25.2 16.5 25.4 6.2 0.0 5.9 12.5 3.7 7.8 19.4 12.1 18.6 5.3 25.1 11.2 16.4 NSFL1C "dJ776F14.1, p47, UBX1, UBXD10, UBXN2C" ENSG00000088833 "NSFL1 cofactor" Q9UNZ2 20 1442162-1473842 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047108, HPA050628" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 1900000 "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA047108: AB_2679935, HPA050628: AB_2681194" "unprognostic (7.55e-2)" "unprognostic (5.26e-2)" "unprognostic (2.51e-2)" "unprognostic (2.47e-1)" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.10e-2)" "unprognostic (1.59e-1)" "unprognostic (4.67e-2)" "unprognostic (2.58e-1)" "unprognostic (4.97e-2)" "unprognostic (6.90e-2)" "unprognostic (5.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.44e-2)" "unprognostic (7.50e-3)" 22.8 37.7 38.3 13.5 39.5 27.8 21.5 37.0 45.9 23.2 41.6 23.0 14.9 22.5 26.8 28.5 26.1 13.5 29.1 39.7 38.6 21.4 26.3 18.0 15.2 39.0 39.0 25.7 15.5 23.9 14.1 21.1 39.8 20.9 18.4 22.6 19.3 26.4 69.0 36.6 17.6 22.9 36.4 19.8 18.0 14.8 38.6 21.0 20.0 43.3 18.6 22.4 21.6 39.7 55.6 64.4 35.9 32.0 30.5 31.4 28.7 21.0 41.8 57.7 41.3 53.9 43.1 31.6 16.6 47.8 47.2 50.4 25.9 70.3 40.8 12.3 25.1 29.8 10.3 61.4 33.8 30.7 16.4 23.5 33.3 55.3 20.3 30.8 46.8 23.4 42.5 26.5 36.2 29.1 31.4 54.7 40.7 42.5 65.4 14.7 41.1 29.8 68.6 37.1 20.5 23.4 29.6 59.8 26.7 18.8 36.5 22.0 37.8 38.7 29.4 23.9 40.2 21.9 41.8 24.7 28.9 43.0 29.3 31.4 21.3 80.3 20.0 26.6 19.7 35.0 21.2 19.5 29.7 36.0 23.4 20.7 69.1 16.7 28.1 23.1 28.2 25.5 38.3 39.5 37.0 45.9 39.7 38.6 39.0 39.0 39.8 36.4 38.6 39.7 34.6 22.4 23.2 17.3 36.1 89.2 63.5 106.3 44.3 60.2 28.6 26.0 35.4 24.3 57.8 31.3 22.9 150.7 29.7 68.2 56.7 104.7 23.0 51.0 29.6 44.3 43.6 41.0 24.0 94.5 146.0 41.1 30.5 54.9 40.5 49.1 31.1 42.2 81.1 70.7 24.8 42.5 61.1 43.7 43.6 38.8 39.1 43.8 42.7 14.0 52.9 61.7 32.0 17.6 31.2 123.4 65.7 46.3 41.8 76.0 66.4 73.8 43.2 44.5 78.9 44.2 64.7 106.1 103.2 55.1 75.7 151.6 31.6 48.9 44.0 88.5 NSG1 "D4S234E, NEEP21, P21" ENSG00000168824 "Neuronal vesicle trafficking associated 1" P42857 4 4348140-4419058 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.7;pituitary gland: 135.1;skin 1: 120.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 222.4;Cytotrophoblasts: 120.2;Granulosa cells: 128.8;Melanocytes: 291.7;Suprabasal keratinocytes: 178.2" "Cancer enriched" "Detected in many" 4 "melanoma: 61.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 45.2;MAIT T-cell: 61.9;memory CD4 T-cell: 42.2;memory CD8 T-cell: 37.1;naive CD8 T-cell: 27.6" "Lineage enriched" "Detected in many" 57 "T-cells: 61.9" "Cell line enhanced" "Detected in many" "HAP1: 84.7;SCLC-21H: 168.6;SH-SY5Y: 82.5;SK-MEL-30: 80.9;TIME: 204.6;U-698: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "unprognostic (3.21e-3)" "unprognostic (2.33e-1)" "unprognostic (5.29e-3)" "unprognostic (7.60e-2)" "unprognostic (8.06e-2)" "unprognostic (1.49e-1)" "unprognostic (1.32e-3)" "unprognostic (3.47e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-3)" "prognostic favorable (9.49e-4)" "unprognostic (2.50e-1)" "unprognostic (6.85e-2)" "unprognostic (4.21e-2)" "unprognostic (7.33e-2)" "unprognostic (2.85e-1)" "unprognostic (7.41e-2)" 5.0 25.3 29.0 4.2 33.1 1.0 6.0 59.6 50.7 17.1 5.3 7.9 6.8 7.8 2.1 30.7 20.1 1.3 5.9 18.4 95.7 4.4 0.5 1.5 3.2 57.1 64.8 46.3 1.8 0.1 135.1 18.3 58.8 22.8 7.1 32.3 6.7 18.2 0.7 120.9 5.8 6.9 24.2 2.2 8.0 16.0 45.4 9.5 0.5 3.0 3.5 13.3 30.1 24.2 0.2 0.1 0.8 0.5 0.0 0.0 14.6 0.3 0.0 0.2 0.0 1.3 0.4 0.0 10.4 0.5 3.3 2.4 84.7 5.5 0.4 0.0 3.0 0.0 0.2 0.0 4.1 0.0 0.0 0.1 12.0 0.0 2.3 0.0 14.6 22.3 0.0 0.1 1.3 0.0 6.8 0.5 10.1 0.1 0.4 0.1 0.0 0.4 0.0 4.8 168.6 82.5 0.6 0.2 80.9 7.0 0.9 0.3 204.6 0.0 13.0 0.2 0.3 0.1 0.4 75.9 0.1 0.2 0.4 0.2 0.1 0.1 45.2 0.1 61.9 0.1 42.2 37.1 0.1 0.1 10.4 27.6 1.0 0.9 0.2 0.1 4.5 15.7 29.0 33.1 59.6 50.7 18.4 95.7 57.1 64.8 58.8 24.2 45.4 24.2 1.6 9.6 0.0 5.9 0.4 86.8 83.4 47.9 31.3 222.4 0.7 24.3 0.0 0.0 13.2 0.0 4.2 120.2 6.0 0.0 0.0 0.0 31.2 10.3 1.4 2.1 2.4 0.0 16.6 0.0 15.2 24.9 0.0 16.4 1.3 128.8 1.8 0.0 8.2 8.4 32.2 0.0 4.1 0.0 13.6 44.2 3.1 1.3 291.7 6.5 0.4 6.4 20.6 1.5 4.0 0.1 0.2 5.7 0.7 19.9 0.0 20.4 1.7 24.3 0.0 0.2 10.8 2.9 14.4 44.8 178.2 76.8 17.0 96.0 0.3 77.0 NSUN7 FLJ14001 ENSG00000179299 "NOP2/Sun RNA methyltransferase family member 7" Q8NE18 4 40749925-40811184 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.5" "Cell type enhanced" "Detected in many" "Early spermatids: 47.5;Late spermatids: 75.6;Respiratory ciliated cells: 36.4;Spermatocytes: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Cell line enhanced" "Detected in some" "A-431: 2.6;CAPAN-2: 5.5;Karpas-707: 4.0;MCF7: 2.6;SuSa: 3.0;T-47d: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA020653 Uncertain Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA020653: AB_1848710" "unprognostic (2.32e-1)" "unprognostic (4.22e-1)" "unprognostic (4.77e-2)" "unprognostic (1.50e-1)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.63e-1)" "unprognostic (4.01e-3)" "unprognostic (4.37e-2)" "unprognostic (3.06e-1)" "unprognostic (2.24e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.76e-8)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-2)" 0.6 0.9 0.6 1.0 0.6 0.6 3.8 0.4 0.4 2.5 7.2 2.8 1.7 2.2 2.7 1.8 6.8 1.2 2.1 0.5 1.5 4.7 0.4 3.3 0.3 1.8 2.4 2.3 7.2 3.3 3.6 1.3 1.5 4.5 2.4 0.7 4.8 1.5 0.0 1.5 2.1 1.2 1.2 2.7 3.2 16.5 2.0 0.3 4.7 0.2 0.3 1.3 1.2 0.8 2.6 0.1 1.2 0.0 0.0 0.0 1.7 0.0 0.2 0.1 0.1 1.0 5.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 2.6 0.1 0.0 1.4 0.0 0.3 0.1 0.0 0.0 2.4 0.7 0.6 1.5 0.3 1.7 0.0 3.0 3.9 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.4 0.4 0.5 1.5 1.8 2.4 1.5 1.2 2.0 0.8 0.1 9.6 7.8 3.6 4.3 1.1 3.1 1.5 2.2 0.1 8.6 7.1 3.5 0.0 10.5 9.2 0.0 9.2 0.1 2.7 9.8 5.8 47.5 20.7 0.9 0.6 8.3 0.4 0.7 5.4 3.6 1.2 4.6 5.4 0.0 8.5 0.7 0.2 3.8 0.0 0.9 7.1 4.1 0.8 0.4 75.6 1.5 2.2 0.0 8.4 1.0 2.1 0.0 18.1 1.3 4.7 2.7 0.0 0.3 4.5 2.2 5.5 36.4 0.1 0.0 0.4 0.8 38.9 11.4 8.2 1.0 4.5 0.7 3.4 7.7 5.7 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 NTNG2 "KIAA1857, Lmnt2, NTNG1" ENSG00000196358 "Netrin G2" Q96CW9 9 132161676-132244526 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Autism spectrum disorder, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 40.4;brain: 74.6;retina: 26.7" "Cell type enhanced" "Detected in many" "Astrocytes: 34.9;Bipolar cells: 69.6;Cone photoreceptor cells: 171.0;Rod photoreceptor cells: 108.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "basal ganglia: 74.6" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "HL-60: 6.8;HMC-1: 16.2;NB-4: 39.0;U-937: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071290 Approved "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA071290: AB_2686381" "unprognostic (5.01e-2)" "unprognostic (2.95e-2)" "unprognostic (4.12e-2)" "unprognostic (1.01e-1)" "unprognostic (3.59e-1)" "unprognostic (7.67e-2)" "unprognostic (2.73e-2)" "unprognostic (2.87e-1)" "unprognostic (4.86e-2)" "unprognostic (1.47e-1)" "unprognostic (2.62e-2)" "prognostic favorable (6.06e-4)" "unprognostic (9.30e-12)" "unprognostic (1.66e-1)" "unprognostic (3.23e-1)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" 0.6 1.9 18.6 1.1 74.6 40.4 0.2 13.3 25.6 0.8 0.0 0.5 1.2 0.5 0.3 0.3 0.5 0.8 5.5 17.6 6.5 0.7 0.3 2.9 1.4 11.5 5.4 0.2 1.0 4.4 1.7 0.5 14.7 6.2 0.2 26.7 0.8 1.1 0.4 0.4 0.8 0.3 5.0 3.9 0.6 2.1 11.4 0.5 0.4 1.4 0.4 0.8 0.6 11.5 0.0 0.5 0.2 0.6 0.6 0.1 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.2 0.0 0.0 1.1 0.2 0.1 0.1 0.0 0.9 6.8 16.2 0.1 0.0 0.2 0.1 1.4 0.0 1.3 0.0 0.0 0.5 0.2 0.3 39.0 1.4 0.0 0.2 0.4 0.4 0.2 0.0 0.0 4.6 4.2 0.2 0.0 0.1 0.0 0.0 0.6 0.1 0.9 2.8 3.6 0.1 0.1 0.0 0.0 1.3 10.0 1.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 18.6 74.6 13.3 25.6 17.6 6.5 11.5 5.4 14.7 5.0 11.4 11.5 0.8 0.0 0.6 34.9 0.5 0.3 0.6 0.0 0.6 69.6 0.1 1.0 3.0 0.0 0.6 0.0 171.0 0.1 5.0 0.0 0.0 0.3 1.4 0.6 2.4 1.3 0.0 0.4 8.1 0.0 0.0 1.9 0.0 1.1 1.3 0.9 0.7 0.1 0.7 1.7 3.6 0.2 0.0 0.3 0.3 1.3 0.6 1.2 1.8 8.4 0.9 20.3 3.1 11.1 21.5 0.1 0.0 1.2 2.0 2.3 0.0 0.1 0.0 108.3 6.6 2.4 1.8 0.5 0.2 0.2 0.3 0.1 1.2 4.3 0.1 0.3 NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302063-205321745 "Enzymes, Metabolic proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 56.7;vagina: 45.3" "Cell type enhanced" "Detected in many" "Ductal cells: 46.9;Endometrial ciliated cells: 45.3;Glandular and luminal cells: 52.4;Intestinal goblet cells: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 120.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 44.1;RPMI-8226: 36.1;RPTEC TERT1: 40.9;SuSa: 45.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "HPA008958: AB_1080040" "unprognostic (2.24e-2)" "unprognostic (6.33e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.01e-7)" "unprognostic (8.24e-3)" "unprognostic (1.58e-2)" "unprognostic (3.00e-2)" "unprognostic (1.08e-2)" "unprognostic (1.74e-1)" "unprognostic (9.19e-2)" "prognostic favorable (7.94e-6)" "unprognostic (3.71e-2)" "unprognostic (3.17e-2)" "unprognostic (4.90e-2)" "unprognostic (5.80e-2)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" 2.1 3.7 1.3 7.7 1.9 11.4 0.9 4.6 1.7 31.0 3.2 8.0 16.5 1.6 1.3 56.7 4.0 1.7 1.2 1.2 1.3 28.2 5.1 10.3 11.5 2.1 1.8 1.3 16.0 0.8 3.0 4.4 2.0 1.9 8.8 0.5 15.1 1.6 0.7 22.4 12.5 1.2 1.4 13.1 2.5 3.7 2.2 3.9 16.1 1.1 8.0 3.1 45.3 4.1 4.3 23.1 13.7 0.6 0.3 0.6 44.1 5.5 5.7 14.7 5.9 24.4 0.8 7.0 3.2 1.5 24.1 8.3 3.2 8.3 6.3 0.0 0.4 0.0 1.4 4.2 9.3 0.0 0.1 2.6 6.1 8.6 5.0 3.3 0.7 0.0 0.9 1.7 2.8 1.0 0.0 0.1 8.9 3.1 0.7 0.0 1.0 36.1 40.9 0.1 2.1 0.2 1.6 6.5 0.7 45.6 6.6 0.1 1.7 5.3 2.5 0.6 8.7 12.1 2.0 4.4 0.8 0.0 2.1 11.2 16.5 40.1 10.3 11.8 7.6 37.9 12.7 12.3 10.4 39.3 27.9 21.9 120.4 17.5 13.1 4.1 8.1 17.4 1.3 1.9 4.6 1.7 1.2 1.3 2.1 1.8 2.0 1.4 2.2 4.1 2.0 6.4 6.8 0.3 28.0 1.1 3.2 3.7 13.1 1.1 1.9 2.2 2.7 20.0 2.9 33.1 0.0 9.2 7.1 34.9 5.9 46.9 2.0 45.3 7.5 5.9 10.8 2.7 0.1 1.8 29.1 3.7 7.7 52.4 0.0 2.4 0.7 2.6 4.7 0.0 0.4 43.0 18.3 12.3 11.1 2.1 0.0 8.9 7.2 3.7 38.5 1.3 18.6 0.5 3.5 6.9 7.8 0.0 18.5 2.5 18.3 17.2 7.7 0.5 6.6 2.4 5.5 0.9 1.1 21.5 5.4 4.1 5.7 0.5 22.0 0.5 NUDT19 RP2 ENSG00000213965 "Nudix hydrolase 19" A8MXV4 19 32691961-32713796 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042761 Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 49: Eosinophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "HPA042761: " "unprognostic (1.20e-1)" "unprognostic (2.90e-1)" "unprognostic (2.35e-3)" "unprognostic (6.61e-3)" "unprognostic (2.62e-2)" "unprognostic (2.44e-1)" "unprognostic (6.18e-3)" "unprognostic (1.97e-1)" "unprognostic (3.14e-2)" "unprognostic (2.19e-1)" "unprognostic (2.99e-1)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (2.64e-2)" "unprognostic (2.81e-1)" "unprognostic (1.23e-1)" "prognostic favorable (1.35e-4)" 5.1 11.7 4.0 4.1 4.1 8.4 4.6 3.9 4.5 3.9 9.4 6.9 7.1 3.6 5.4 11.1 3.6 2.9 10.6 4.1 5.1 6.3 6.9 6.4 5.8 4.6 4.3 3.7 8.4 7.1 4.0 4.5 4.8 7.5 7.3 8.3 6.9 3.5 23.9 8.9 6.2 4.3 4.3 5.2 8.1 2.8 4.6 3.1 3.6 13.0 5.1 6.3 5.6 4.6 21.5 24.7 2.7 24.0 8.1 10.5 0.2 11.9 4.4 8.7 8.2 14.0 11.6 0.1 14.0 13.8 6.7 13.7 16.7 13.9 11.4 24.8 10.0 27.7 9.3 5.0 11.2 20.9 8.2 8.5 18.1 7.4 17.8 10.1 13.0 4.2 21.6 15.3 15.9 14.3 0.1 19.3 2.9 5.9 11.5 0.1 5.2 12.1 14.4 15.7 10.7 15.4 21.2 17.7 15.9 4.7 9.8 25.4 10.4 11.9 7.7 12.0 21.5 17.8 16.3 6.9 14.4 20.0 11.2 11.1 26.5 15.4 18.2 36.7 20.0 13.0 18.9 22.6 19.5 9.4 14.9 20.4 5.1 32.2 42.4 15.9 23.6 11.9 4.0 4.1 3.9 4.5 4.1 5.1 4.6 4.3 4.8 4.3 4.6 4.6 5.9 12.8 14.5 7.5 6.4 21.9 9.4 4.6 8.0 14.5 12.0 6.6 22.8 2.8 6.2 7.3 12.5 11.0 9.1 10.6 27.4 2.9 7.7 8.5 9.3 7.3 12.1 10.3 5.9 11.5 11.5 6.6 3.1 10.7 1.3 11.3 13.2 12.5 14.3 3.3 6.7 12.7 8.2 17.6 11.6 3.7 4.1 10.2 12.4 4.7 10.7 4.6 4.1 6.6 7.4 12.0 13.1 9.4 4.1 12.0 15.7 18.8 6.5 30.4 0.0 6.9 7.4 1.6 2.2 9.9 31.5 7.8 9.1 22.3 18.4 10.6 NUF2 "CDCA1, CT106, NUF2R" ENSG00000143228 "NUF2 component of NDC80 kinetochore complex" Q9BZD4 1 163266576-163355764 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 28.4;lymphoid tissue: 26.0;testis: 53.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 60.8;Spermatocytes: 208.2;Spermatogonia: 40.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA059692, HPA076604" Supported Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA059692: AB_2684103, HPA076604: " "unprognostic (9.41e-2)" "unprognostic (2.61e-1)" "unprognostic (2.56e-1)" "unprognostic (5.32e-3)" "unprognostic (6.20e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (1.04e-5)" "prognostic unfavorable (9.16e-4)" "prognostic unfavorable (4.83e-4)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.75e-4)" "unprognostic (3.70e-2)" "unprognostic (0.00e+0)" "unprognostic (9.79e-2)" "unprognostic (7.88e-2)" "unprognostic (2.69e-1)" "unprognostic (5.96e-2)" 0.8 0.6 0.5 6.9 0.8 28.4 1.2 0.5 0.8 1.0 0.4 4.2 4.3 1.1 0.3 5.8 0.4 1.0 0.3 0.6 0.6 0.3 0.7 0.9 18.2 0.9 0.8 0.4 0.2 0.6 0.2 4.7 0.9 0.4 5.3 1.5 0.9 0.3 0.1 4.1 4.3 2.3 0.7 3.6 2.6 53.5 0.8 26.0 0.5 0.2 16.7 1.8 1.8 1.0 90.8 30.8 80.5 33.9 2.5 8.1 43.6 55.9 39.3 88.9 77.3 23.7 77.7 77.4 45.5 22.6 37.0 51.6 49.6 21.0 111.5 81.4 35.6 30.3 34.8 34.4 0.3 53.0 60.2 1.0 2.0 45.0 31.6 16.8 41.1 74.5 58.1 103.9 85.0 17.6 97.3 70.6 43.9 66.1 47.0 65.0 70.3 68.4 25.3 12.4 59.9 68.9 29.9 32.2 30.6 49.7 49.3 109.5 29.4 65.9 73.8 50.1 115.1 73.9 111.5 148.9 22.0 42.9 74.7 1.4 0.1 1.3 1.2 0.0 0.5 0.6 1.8 1.2 0.2 0.7 1.2 1.0 0.4 1.8 0.1 0.3 4.3 0.4 0.5 0.8 0.5 0.8 0.6 0.6 0.9 0.8 0.9 0.7 0.8 1.0 0.5 0.0 0.5 1.3 5.3 5.9 1.9 4.2 1.2 1.2 1.3 2.7 0.9 0.0 3.3 0.0 0.0 21.7 3.6 2.6 0.0 0.8 17.7 2.5 2.5 1.8 0.0 60.8 1.1 0.2 29.7 3.4 5.6 3.0 4.5 18.3 3.3 0.4 14.0 0.0 1.4 3.3 0.0 5.2 3.6 21.4 2.5 3.1 0.0 1.0 0.9 2.0 6.2 0.5 3.6 0.2 0.1 2.2 17.8 0.8 0.9 0.2 0.7 2.3 6.6 0.9 4.2 208.2 40.3 10.6 2.4 4.0 5.0 1.7 9.0 3.8 NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 88.6;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 266.7;Extravillous trophoblasts: 121.2;Granulosa cells: 93.3;Spermatocytes: 99.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 10.7;T-reg: 7.7" "Group enriched" "Detected in many" 15 "granulocytes: 10.7;T-cells: 7.7" "Low cell line specificity" "Detected in many" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" 1.8 14.1 0.2 7.8 0.2 88.6 1.5 0.3 0.4 3.6 0.3 6.1 7.0 1.1 0.1 17.7 1.1 1.0 1.1 0.2 0.2 2.6 5.0 3.8 28.7 0.3 0.4 4.4 1.3 0.0 0.6 6.5 0.3 1.1 8.0 0.1 3.6 0.6 5.4 9.4 7.4 2.7 0.2 7.8 4.5 10.9 0.3 101.5 0.9 0.1 31.5 1.9 6.4 0.3 146.0 38.3 165.1 64.6 3.5 5.9 37.0 107.4 74.6 138.9 130.6 58.4 67.0 63.5 42.5 44.4 99.1 107.6 104.2 46.2 132.4 98.5 62.3 149.6 102.0 50.7 0.2 67.3 57.2 0.9 1.3 69.1 37.3 21.7 72.0 104.2 70.1 237.5 105.7 30.7 147.5 82.2 59.8 139.8 55.0 136.5 156.5 67.5 42.4 29.3 85.7 55.2 129.8 88.5 25.7 46.0 106.2 76.1 33.7 89.9 104.8 101.5 206.2 81.3 145.8 200.5 42.1 163.6 171.2 10.7 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.5 0.3 0.6 0.0 0.3 0.2 0.4 0.0 0.3 7.7 0.5 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.4 0.3 0.2 0.3 0.3 1.9 0.0 1.5 1.3 14.2 38.5 10.3 21.2 31.9 0.9 9.9 13.7 1.1 17.2 5.0 0.0 0.0 72.2 13.4 14.4 3.9 2.3 33.2 10.7 11.6 7.3 3.0 266.7 1.4 0.5 121.2 14.6 25.5 21.8 7.0 93.3 10.8 3.9 36.7 0.0 1.5 15.5 24.4 13.8 22.7 14.6 0.3 17.5 3.6 1.9 6.1 1.9 4.1 1.0 1.3 1.5 0.4 1.9 57.2 5.3 2.6 5.4 1.1 1.0 0.0 2.8 12.1 99.6 59.9 69.5 24.9 19.3 22.9 38.8 30.0 10.3 NVL NVL2 ENSG00000143748 "Nuclear VCP like" O15381 1 224227334-224330189 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028207, HPA028219, HPA028224, HPA028654" Supported Enhanced Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli "HPA028207: AB_10601382, HPA028219: AB_2672526, HPA028224: AB_2672529, HPA028654: AB_2672714" "unprognostic (1.50e-1)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (5.77e-5)" "prognostic favorable (2.95e-4)" "unprognostic (4.43e-2)" "unprognostic (7.14e-2)" "unprognostic (3.15e-1)" "unprognostic (2.42e-1)" "prognostic unfavorable (4.10e-11)" "unprognostic (1.67e-1)" "unprognostic (2.01e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" 7.0 7.7 5.5 8.7 5.7 9.8 10.7 7.8 7.5 9.5 6.5 9.1 6.3 9.0 7.7 7.2 8.8 5.6 5.9 5.3 6.4 8.7 6.1 8.0 12.5 5.4 5.3 10.6 8.8 9.5 10.3 13.0 5.6 9.0 10.6 12.8 7.4 7.9 6.5 15.7 8.2 8.1 4.7 10.4 7.2 6.6 5.6 13.0 10.2 5.2 12.1 8.8 8.9 7.5 28.8 15.8 31.2 25.2 11.5 16.6 31.6 22.0 16.5 30.6 27.0 23.4 23.4 39.6 22.5 14.7 11.7 26.1 37.3 22.2 31.5 30.5 47.0 16.4 25.5 11.3 20.3 39.1 28.8 13.5 16.9 26.8 28.5 14.3 19.2 23.0 48.9 23.8 19.1 21.3 30.6 18.3 47.5 20.0 26.1 34.2 37.3 24.8 17.8 19.2 27.5 22.9 34.2 53.1 31.9 25.6 24.3 32.1 19.8 23.2 14.9 27.1 42.9 15.6 33.3 39.3 15.1 30.2 24.8 13.9 7.8 8.4 11.5 11.8 11.7 13.5 11.8 9.1 8.7 9.0 9.9 10.0 0.8 11.9 16.4 9.0 9.3 7.8 5.5 5.7 7.8 7.5 5.3 6.4 5.4 5.3 5.6 4.7 5.6 7.5 10.2 22.4 23.1 21.2 14.3 5.2 4.6 7.8 4.0 14.5 7.9 8.3 10.5 7.2 12.2 1.8 10.4 21.5 12.6 26.9 13.7 9.5 10.1 10.0 11.6 9.3 4.2 7.2 32.1 8.4 14.0 9.3 5.6 7.3 16.4 13.4 4.6 4.5 10.7 10.1 31.0 12.6 10.2 6.5 5.7 3.1 9.6 8.1 5.4 26.2 8.7 9.7 15.5 24.6 43.0 7.0 23.4 10.9 12.3 3.7 7.0 8.1 16.7 20.4 0.0 8.5 10.1 17.5 11.3 7.3 4.5 18.3 12.9 11.4 14.7 3.7 NWD1 ENSG00000188039 "NACHT and WD repeat domain containing 1" Q149M9 19 16719847-16817963 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "choroid plexus: 192.4" "Group enriched" "Detected in some" 4 "Astrocytes: 41.4;Endometrial ciliated cells: 83.9;Respiratory ciliated cells: 92.0" "Cancer enriched" "Detected in many" 6 "prostate cancer: 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-937: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075476 Approved Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli, Cytosol" "HPA075476: " "unprognostic (5.29e-3)" "unprognostic (3.08e-2)" "unprognostic (3.05e-2)" "prognostic favorable (2.55e-4)" "unprognostic (2.49e-1)" "unprognostic (4.20e-4)" "unprognostic (6.54e-2)" "unprognostic (5.15e-2)" "unprognostic (2.95e-1)" "unprognostic (1.60e-1)" "unprognostic (7.94e-2)" "unprognostic (1.76e-1)" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (5.09e-2)" "unprognostic (3.53e-2)" "unprognostic (3.25e-1)" 0.0 0.0 5.4 0.0 6.2 0.1 0.2 7.6 4.9 1.3 192.4 0.5 0.0 0.2 0.4 0.2 12.6 0.2 0.0 12.2 5.2 0.2 0.0 1.3 0.0 6.2 8.8 0.0 1.5 0.0 0.7 0.0 6.1 6.8 0.1 1.1 1.3 1.8 0.0 0.2 0.0 0.0 3.2 0.0 0.8 0.2 10.1 0.2 0.7 0.0 0.0 0.1 0.0 3.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 2.4 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.4 6.2 7.6 4.9 12.2 5.2 6.2 8.8 6.1 3.2 10.1 3.7 0.0 0.0 1.5 41.4 0.3 0.3 1.7 3.5 0.0 0.2 0.5 0.3 0.9 0.0 4.5 0.0 0.0 0.1 0.0 0.4 0.0 0.1 17.9 83.9 0.8 0.3 1.2 0.0 2.4 0.0 0.2 0.3 0.0 3.7 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.6 2.0 0.0 0.4 3.3 0.6 0.3 0.0 0.0 0.0 8.9 0.0 1.5 1.2 0.2 0.4 0.0 0.0 4.0 0.0 0.1 92.0 0.6 0.0 1.1 1.4 0.0 0.2 0.0 0.1 1.1 0.4 0.0 0.4 1.4 NXN "FLJ12614, NRX" ENSG00000167693 Nucleoredoxin Q6DKJ4 17 799310-979776 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Oxidoreductase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 99.2" "Cell type enhanced" "Detected in many" "Late spermatids: 91.5;Microglial cells: 87.1;Urothelial cells: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 100.7;HHSteC: 106.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023566 Approved Approved Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA023566: AB_1854737" "unprognostic (1.68e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-2)" "unprognostic (3.48e-2)" "unprognostic (7.29e-2)" "unprognostic (1.00e-1)" "unprognostic (1.75e-2)" "unprognostic (6.98e-2)" "unprognostic (1.65e-3)" "unprognostic (2.27e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-1)" "unprognostic (5.76e-2)" "unprognostic (3.56e-2)" "unprognostic (2.34e-1)" "unprognostic (2.68e-2)" "unprognostic (2.05e-3)" 16.9 7.5 14.5 8.7 13.1 1.1 19.0 12.1 15.0 41.3 21.9 70.0 5.4 47.2 11.6 27.2 29.1 13.7 16.0 13.5 13.2 14.4 9.5 24.6 5.0 13.6 14.9 14.8 33.6 2.6 6.8 14.5 14.0 39.7 4.6 8.9 20.7 25.0 99.2 24.9 19.8 23.1 12.8 6.4 28.3 9.6 17.1 13.1 12.9 35.7 13.8 43.4 42.5 12.3 14.3 21.2 81.5 52.8 5.3 1.1 4.5 44.6 29.3 46.1 73.3 50.4 14.8 0.6 83.6 57.5 10.8 100.7 52.9 83.2 36.3 0.6 30.9 0.2 12.7 44.8 106.1 0.3 2.3 32.2 75.6 6.0 36.0 9.3 41.9 11.3 7.4 0.0 12.3 5.8 2.9 1.0 39.2 42.3 1.4 6.2 2.1 0.3 32.9 20.6 20.9 13.6 21.1 0.1 1.1 50.3 14.9 13.0 0.0 1.0 19.1 0.4 12.5 7.5 5.2 0.4 0.4 1.7 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.2 0.0 0.2 0.2 0.0 14.5 13.1 12.1 15.0 13.5 13.2 13.6 14.9 14.0 12.8 17.1 12.3 36.5 32.1 11.7 13.4 0.9 17.5 53.6 18.8 12.0 2.6 7.6 12.4 8.6 2.8 13.2 3.7 33.3 0.4 0.4 0.1 0.0 3.5 25.1 20.2 52.1 34.7 1.8 2.7 6.9 24.6 0.7 23.0 1.1 12.6 1.3 1.0 14.6 8.2 6.3 5.0 10.7 0.0 0.0 0.3 8.8 91.5 15.5 1.9 7.2 87.1 0.6 11.4 0.0 23.1 3.3 5.9 0.0 7.2 0.4 36.0 0.0 0.5 15.5 18.0 13.1 14.5 19.2 13.1 10.1 13.1 12.4 0.4 1.5 27.2 0.0 59.0 NYAP1 "C7orf51, FLJ37538, KIAA1486L" ENSG00000166924 "Neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1" Q6ZVC0 7 100483927-100494802 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;pituitary gland: 22.0" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Bipolar cells: 6.2;Excitatory neurons: 11.1;Granulosa cells: 5.6;Horizontal cells: 13.5;Inhibitory neurons: 10.3" "Cancer enhanced" "Detected in some" "glioma: 4.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 7.8;HUVEC TERT2: 3.9;SH-SY5Y: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022251 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Golgi apparatus" "HPA022251: AB_1848915" "unprognostic (6.59e-4)" "unprognostic (2.67e-2)" "unprognostic (1.82e-2)" "unprognostic (2.51e-4)" "unprognostic (2.89e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" "unprognostic (4.86e-2)" "unprognostic (2.54e-2)" "unprognostic (2.49e-3)" "unprognostic (1.81e-1)" "unprognostic (3.25e-1)" "unprognostic (1.20e-1)" "unprognostic (3.06e-2)" "unprognostic (4.31e-1)" "unprognostic (8.65e-2)" 2.1 2.5 6.4 0.3 8.4 0.1 1.6 0.0 22.5 2.9 0.0 1.3 0.2 4.6 0.0 1.1 2.2 0.2 0.7 11.4 2.9 1.9 0.4 0.3 0.1 6.6 0.6 5.3 0.9 0.0 22.0 0.3 6.8 2.0 0.1 1.9 0.9 0.9 0.1 1.4 0.8 0.5 0.0 0.8 0.8 9.1 2.0 0.1 0.7 0.1 0.0 0.6 2.0 8.2 0.0 1.1 3.0 1.4 2.0 1.2 0.2 0.1 1.0 0.1 0.4 0.4 0.2 0.0 1.0 0.3 7.8 0.1 0.6 0.1 0.0 1.4 0.2 0.1 0.3 0.2 1.4 0.0 0.8 1.3 0.0 0.4 0.5 0.3 3.9 0.2 0.5 0.1 0.0 0.3 0.0 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.9 9.4 0.3 0.2 1.0 1.1 0.1 0.0 1.4 0.0 1.9 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 8.4 0.0 22.5 11.4 2.9 6.6 0.6 6.8 0.0 2.0 8.2 3.2 0.0 0.0 9.4 0.0 0.1 0.2 0.1 0.6 6.2 0.3 1.9 1.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.2 0.4 1.4 0.0 0.8 11.1 0.0 0.0 0.9 0.0 0.4 0.0 5.6 0.7 0.0 0.1 13.5 10.3 0.1 0.0 0.0 0.7 0.7 2.5 0.1 0.0 2.8 0.0 3.3 0.0 2.5 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.1 0.2 1.0 0.0 0.5 0.7 1.3 2.6 0.2 0.1 0.0 0.1 0.8 0.0 0.0 OBP2A "hOBPIIa, LCN13, OBP" ENSG00000122136 "Odorant binding protein 2A" Q9NY56 9 135546126-135549969 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "fallopian tube: 24.9" "Cell type enhanced" "Detected in some" "Breast glandular cells: 2.4;Breast myoepithelial cells: 3.4;Late spermatids: 1.8;Leydig cells: 1.5;Melanocytes: 1.8" "Cancer enriched" "Detected in some" 6 "ovarian cancer: 18.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "U-266/70: 1.6;U-266/84: 6.4" HPA055955 Uncertain "Secreted in other tissues" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: U-266 - Nucleosome" "Cluster 44: Endometrium - Transcription" "HPA055955: AB_2682985" "unprognostic (2.30e-1)" "unprognostic (3.68e-1)" "unprognostic (4.63e-1)" "unprognostic (1.66e-2)" "unprognostic (2.17e-1)" "unprognostic (3.20e-1)" "unprognostic (2.75e-1)" "unprognostic (7.65e-2)" "unprognostic (2.23e-2)" "unprognostic (8.27e-2)" "unprognostic (1.91e-1)" "unprognostic (6.83e-11)" "unprognostic (5.17e-2)" "unprognostic (3.61e-1)" "unprognostic (1.26e-1)" "unprognostic (3.84e-1)" 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.9 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.5 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 OBP2B "hOBPIIb, LCN14" ENSG00000171102 "Odorant binding protein 2B" Q9NPH6 9 133205277-133209250 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 2.7;testis: 10.0" "Group enriched" "Detected in some" 9 "Breast glandular cells: 17.7;Breast myoepithelial cells: 29.1" "Group enriched" "Detected in many" 8 "breast cancer: 7.8;endometrial cancer: 16.2;ovarian cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: Glandular cells - Unknown function" "unprognostic (1.40e-1)" "unprognostic (5.70e-2)" "unprognostic (9.45e-3)" "unprognostic (6.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.30e-1)" "unprognostic (7.03e-2)" "unprognostic (6.82e-6)" "unprognostic (2.00e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.4 0.3 0.0 0.0 0.0 17.7 29.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 2.5 1.2 0.1 1.8 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.1 OC90 PLA2L ENSG00000253117 "Otoconin 90" Q02509 8 132024216-132059382 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.92e-1)" "unprognostic (2.93e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OCA2 "BEY, BEY1, BEY2, D15S12, EYCL, EYCL2, EYCL3, P" ENSG00000104044 "OCA2 melanosomal transmembrane protein" Q04671 15 27754875-28099315 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 28.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 30.9;Inhibitory neurons: 40.8;Melanocytes: 42.7;Peritubular cells: 14.7" "Cancer enriched" "Detected in many" 17 "melanoma: 19.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SK-MEL-30: 24.6" "Low region specificity" "Detected in some" HPA036402 Approved "Plasma membrane,Cytosol" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Cytosol "HPA036402: " "unprognostic (6.07e-3)" "unprognostic (1.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.82e-2)" "unprognostic (4.60e-4)" "unprognostic (7.11e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.47e-2)" "unprognostic (4.95e-2)" "unprognostic (1.96e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-6)" "unprognostic (2.61e-1)" "unprognostic (4.21e-1)" "unprognostic (3.28e-2)" "unprognostic (2.28e-2)" 0.3 0.0 1.8 0.1 1.8 0.0 0.3 0.1 1.8 1.2 28.1 0.1 0.0 0.2 0.3 2.2 1.1 0.0 0.3 1.4 1.8 0.3 0.1 0.6 1.8 0.5 0.9 0.3 0.0 0.0 0.8 1.5 0.6 0.6 0.0 0.0 0.8 1.0 0.2 6.4 0.2 0.0 0.0 1.1 0.1 1.9 2.4 0.4 4.2 0.0 0.7 0.2 2.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.1 5.6 0.0 0.0 24.6 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 0.1 1.8 1.4 1.8 0.5 0.9 0.6 0.0 2.4 1.0 0.0 0.0 0.0 0.7 0.0 2.0 0.1 0.1 0.6 0.0 0.0 0.4 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.4 5.6 0.2 0.1 0.0 0.0 30.9 0.0 0.1 1.4 0.0 2.8 0.0 2.3 0.0 0.0 0.1 0.0 40.8 0.1 0.0 0.0 0.9 3.0 9.3 0.1 42.7 0.0 0.0 0.0 0.0 2.5 0.8 0.0 1.2 14.7 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.8 4.2 4.9 6.1 0.9 0.1 0.1 0.4 0.1 0.2 ODF3L1 MGC48986 ENSG00000182950 "Outer dense fiber of sperm tails 3 like 1" Q8IXM7 15 75724041-75727688 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 22.6" "Cell type enriched" "Detected in some" 9 "Early spermatids: 111.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.0;HeLa: 1.2;U-87 MG: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (6.24e-2)" "unprognostic (1.97e-2)" "unprognostic (4.58e-2)" "unprognostic (8.42e-2)" "unprognostic (2.08e-2)" "unprognostic (1.41e-1)" "unprognostic (2.77e-1)" "unprognostic (1.56e-1)" "unprognostic (1.99e-1)" "unprognostic (2.74e-1)" "unprognostic (7.55e-4)" "unprognostic (9.65e-2)" "unprognostic (9.96e-3)" "unprognostic (6.40e-2)" "unprognostic (4.14e-2)" "unprognostic (8.94e-3)" "unprognostic (1.45e-2)" 1.4 0.1 0.3 0.3 0.2 0.3 1.1 1.3 0.4 0.6 0.4 1.4 0.5 1.2 0.1 1.2 1.0 2.6 1.1 0.4 0.1 0.2 1.1 1.6 0.1 0.1 0.5 0.2 0.4 0.1 1.1 0.2 0.1 0.4 0.4 0.0 0.1 0.1 0.1 1.7 0.8 0.9 0.0 0.3 1.7 22.6 0.2 0.6 1.4 0.0 0.1 0.9 0.2 0.1 0.0 1.0 0.3 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.2 0.9 0.0 0.0 0.1 0.0 0.9 0.0 0.6 0.0 0.7 0.4 0.0 1.2 0.2 0.2 0.0 0.0 0.6 0.0 0.2 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 1.3 0.4 0.4 0.1 0.1 0.5 0.1 0.0 0.2 0.1 0.1 0.0 1.1 0.0 0.4 6.1 9.7 0.9 0.0 0.0 0.6 0.3 0.0 0.0 2.5 0.0 0.0 1.6 0.1 0.7 0.0 0.3 111.2 2.7 0.5 0.3 0.0 0.0 0.1 0.0 0.9 2.1 1.5 1.8 0.0 0.2 1.1 0.3 0.4 0.0 0.0 1.2 0.0 0.0 2.7 11.9 0.0 1.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.7 0.8 0.9 1.6 0.7 0.3 0.0 6.6 2.7 1.0 8.0 0.4 0.0 6.5 1.9 0.4 0.1 0.5 4.1 OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;skeletal muscle: 10.3;testis: 20.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.9;Extravillous trophoblasts: 24.0;Spermatocytes: 110.6;Spermatogonia: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" Vesicles "HPA052271: AB_2681780, HPA059602: AB_2684079" "unprognostic (5.17e-2)" "unprognostic (7.26e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (6.94e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (9.34e-5)" "unprognostic (5.51e-2)" "unprognostic (0.00e+0)" "unprognostic (3.84e-2)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (2.86e-2)" 0.6 1.7 0.1 3.3 0.2 10.3 1.2 1.2 0.4 0.9 0.2 4.1 3.5 0.8 0.3 3.8 0.4 0.6 1.5 0.2 0.2 0.3 1.2 0.5 5.8 0.2 0.4 1.5 0.3 0.1 0.1 2.3 0.4 0.5 3.9 0.7 0.8 0.6 10.3 3.3 3.9 1.1 0.1 1.7 1.5 20.9 0.2 9.1 0.4 0.8 5.2 0.7 1.3 0.5 33.7 17.8 34.3 24.9 1.7 2.1 32.4 20.0 9.3 24.5 26.1 31.8 16.2 19.8 17.0 7.7 37.8 51.0 35.7 16.1 19.2 42.4 40.1 42.4 49.8 33.6 0.4 46.5 22.1 0.7 3.2 13.8 14.5 5.2 21.1 40.8 59.4 37.3 16.5 16.3 27.1 34.8 30.9 50.4 37.9 32.9 28.4 30.5 11.1 15.4 53.7 17.5 33.7 34.3 9.6 13.7 33.7 26.3 10.0 24.5 37.3 24.6 36.6 17.0 83.2 71.1 7.1 56.5 35.9 0.0 0.4 0.5 0.2 0.7 0.8 1.0 0.7 0.8 0.7 1.2 1.3 0.8 0.0 1.2 0.4 4.1 3.1 0.8 0.1 0.2 1.2 0.4 0.2 0.2 0.2 0.4 0.4 0.1 0.2 0.5 0.2 0.0 0.5 1.0 2.7 4.1 0.9 3.6 1.2 0.0 1.1 2.2 0.2 0.0 1.8 0.0 0.0 15.0 1.7 2.3 0.0 0.4 12.0 1.9 0.6 0.9 0.0 45.9 2.2 0.4 24.0 1.7 5.1 1.1 1.3 5.2 0.0 0.8 7.5 0.0 2.1 3.0 8.2 2.2 1.8 10.8 0.9 1.2 0.0 0.0 0.6 1.1 2.1 1.5 2.5 0.2 0.5 1.2 10.9 0.4 0.9 0.3 0.0 0.3 6.6 1.0 1.1 110.6 56.8 8.3 2.4 3.8 1.2 2.1 7.6 0.9 OLAH "FLJ11106, SAST, THEDC1" ENSG00000152463 "Oleoyl-ACP hydrolase" Q9NV23 10 15032227-15073853 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.0;testis: 27.0" "Cell type enriched" "Detected in some" 4 "Early spermatids: 537.8" "Cancer enriched" "Detected in some" 4 "testis cancer: 3.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 2.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.6" "Cell line enhanced" "Detected in some" "HSkMC: 3.6;hTCEpi: 4.8;LHCN-M2: 3.6;SK-BR-3: 5.3;SuSa: 2.6;U-266/70: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037947, HPA037948" Enhanced NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA037947: AB_10795028, HPA037948: AB_10805352" "unprognostic (2.01e-1)" "unprognostic (6.12e-2)" "unprognostic (8.20e-3)" "unprognostic (4.04e-3)" "unprognostic (1.92e-1)" "unprognostic (8.09e-2)" "unprognostic (7.12e-2)" "unprognostic (5.12e-2)" "unprognostic (4.55e-1)" "unprognostic (3.74e-2)" "unprognostic (4.70e-1)" "unprognostic (1.69e-1)" "unprognostic (5.22e-10)" "unprognostic (4.55e-2)" "unprognostic (2.09e-1)" "unprognostic (5.11e-2)" "unprognostic (9.78e-2)" 1.5 0.9 1.1 0.2 0.8 1.1 5.5 0.6 1.5 0.8 0.8 0.2 0.1 0.4 0.4 3.0 1.7 1.0 0.2 1.1 0.3 1.1 0.3 1.7 0.3 0.5 0.3 0.2 0.1 0.3 1.0 3.2 0.3 0.3 0.0 0.7 2.7 0.1 0.2 0.7 0.5 0.2 0.2 9.0 0.3 27.0 0.7 0.1 0.4 0.3 0.0 0.2 0.8 1.2 0.0 0.0 0.1 0.2 0.2 0.7 1.2 0.3 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.4 0.1 0.1 0.2 0.1 0.0 0.5 0.0 0.4 3.6 4.8 0.5 0.0 0.0 0.4 0.1 0.2 0.1 3.6 0.0 0.3 0.2 0.2 0.0 0.3 0.4 0.7 0.2 0.0 0.0 0.0 0.1 0.1 5.3 0.0 2.6 0.1 0.1 0.2 0.0 1.8 0.1 0.1 3.1 0.7 0.2 1.1 0.2 0.0 0.8 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 2.6 0.4 0.0 0.5 0.2 0.0 1.1 0.8 0.6 1.5 1.1 0.3 0.5 0.3 0.3 0.2 0.7 1.2 0.7 3.2 0.6 0.3 0.1 0.3 0.5 0.0 0.0 0.1 131.3 0.9 0.4 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 2.7 537.8 0.1 0.2 0.3 0.0 0.0 0.1 0.0 1.7 0.3 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 2.2 0.3 66.1 4.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 8.2 0.0 0.4 0.0 0.0 0.8 0.7 6.6 0.5 1.0 2.8 1.9 0.0 0.3 11.4 0.9 0.1 0.0 0.1 OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936552 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 202.6;skin 1: 94.8" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Basal keratinocytes: 125.0;Muller glia cells: 91.1;Oligodendrocyte precursor cells: 124.7;Suprabasal keratinocytes: 118.1" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.7" "Group enriched" "Detected in many" 26 "granulocytes: 49.7;T-cells: 17.0" "Cell line enhanced" "Detected in many" "AN3-CA: 25.6;ASC diff: 23.4;BJ hTERT+: 18.5;SH-SY5Y: 24.3;U-2 OS: 28.7;WM-115: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA 2700000 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" 36.8 30.7 130.8 3.4 134.5 0.2 25.0 118.5 202.6 17.2 80.7 4.8 2.1 16.7 4.5 5.6 11.1 6.7 10.1 134.0 127.3 9.2 41.9 10.1 7.9 152.5 168.8 9.7 11.2 9.6 19.1 7.1 162.0 10.1 1.1 24.6 10.0 13.4 1.8 94.8 3.8 6.7 130.0 2.5 2.2 10.7 123.2 16.5 13.2 1.0 4.8 3.0 14.1 120.7 0.0 3.7 3.0 25.6 23.4 14.3 1.7 5.6 18.5 1.2 1.5 0.3 2.4 0.1 2.3 4.2 2.1 1.5 9.8 1.7 0.1 0.1 2.1 0.0 0.2 0.3 0.1 0.0 4.3 7.5 1.5 0.1 0.2 0.7 0.1 4.8 0.3 0.3 0.0 8.2 0.3 0.2 15.8 2.5 0.0 0.1 0.0 0.0 0.0 0.9 0.1 24.3 0.9 0.1 5.2 9.7 0.9 0.0 0.3 10.5 28.7 0.1 0.1 0.0 0.0 0.0 0.3 0.0 25.6 21.2 0.0 49.7 6.2 0.0 6.6 0.0 7.0 5.5 0.0 0.0 13.5 8.9 0.5 1.2 0.0 0.1 17.0 2.9 130.8 134.5 118.5 202.6 134.0 127.3 152.5 168.8 162.0 130.0 123.2 120.7 12.9 0.0 0.0 108.4 0.3 125.0 4.7 5.9 8.6 4.9 6.9 13.8 0.8 7.2 0.4 7.3 0.0 0.1 1.0 0.1 1.9 0.9 8.6 0.9 2.2 4.3 1.2 0.4 27.3 2.4 0.0 17.2 0.0 1.0 4.5 6.5 1.4 24.7 0.3 1.7 51.0 0.2 2.0 0.3 32.6 52.8 13.7 0.6 17.8 15.0 0.4 91.1 7.2 124.7 3.5 4.1 0.0 9.8 0.5 7.9 0.0 0.2 0.2 3.7 0.0 7.4 24.3 3.0 10.4 1.4 118.1 0.1 7.7 0.6 0.1 2.9 OLFML2A FLJ00237 ENSG00000185585 "Olfactomedin like 2A" Q68BL7 9 124777133-124814885 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 40.1;Endothelial cells: 21.2;Fibroblasts: 29.0;Skeletal myocytes: 63.0;Smooth muscle cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 160.0;GAMG: 34.0;HeLa: 39.8;hTERT-RPE1: 38.0;WM-115: 64.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021180, HPA022254" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 240000 "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA021180: AB_1854790, HPA022254: AB_1854791" "unprognostic (1.12e-1)" "unprognostic (3.07e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-1)" "unprognostic (4.01e-2)" "unprognostic (1.27e-1)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (1.26e-3)" "unprognostic (7.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (3.73e-5)" "unprognostic (5.72e-3)" "unprognostic (3.30e-2)" "unprognostic (7.91e-2)" "unprognostic (1.05e-2)" 15.4 2.9 2.6 2.7 3.1 0.3 11.1 2.2 4.6 25.0 3.3 29.9 3.3 25.3 2.8 8.2 6.4 4.8 16.4 2.2 2.4 4.3 0.7 10.5 2.4 2.8 2.1 12.0 4.8 4.6 2.8 7.0 2.8 7.4 6.2 2.2 7.0 12.2 10.8 16.0 6.9 16.0 2.1 32.8 5.5 1.1 2.6 3.1 19.1 10.0 3.7 17.6 14.6 2.1 0.8 14.6 1.2 0.4 16.8 160.0 0.1 1.8 8.2 3.5 3.5 0.2 2.2 0.0 3.4 0.1 34.0 25.5 0.4 0.8 4.0 0.0 0.1 0.0 39.8 0.1 0.9 0.0 0.1 11.3 2.7 10.2 1.4 38.0 0.0 0.0 0.0 0.2 1.8 0.4 0.0 0.3 3.4 0.0 0.9 0.0 9.5 0.0 0.0 1.2 0.0 0.1 2.9 0.2 4.3 28.6 3.9 0.5 0.1 5.2 4.6 5.5 0.7 1.9 0.0 0.1 15.2 0.8 64.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.1 2.6 3.1 2.2 4.6 2.2 2.4 2.8 2.1 2.8 2.1 2.6 2.1 40.1 0.0 1.3 0.7 0.4 12.0 5.9 17.5 6.2 0.6 2.9 8.3 13.8 1.5 5.5 0.0 2.1 0.3 0.5 0.0 0.0 0.1 0.7 0.2 1.5 21.2 0.0 0.0 0.4 0.6 0.3 29.0 0.5 0.2 0.0 0.9 3.6 0.1 0.1 0.0 0.6 0.0 4.1 1.5 7.9 1.4 2.8 0.9 10.6 8.4 0.1 0.3 0.0 0.0 0.1 0.0 0.0 1.5 0.1 4.0 0.0 0.1 11.5 4.0 13.1 63.0 36.4 0.4 0.7 4.5 8.4 0.0 0.6 4.2 0.0 3.5 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OLIG1 "BHLHB6, bHLHe21" ENSG00000184221 "Oligodendrocyte transcription factor 1" Q8TAK6 21 33070141-33072413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 178.0" "Cell type enhanced" "Detected in some" "Distal tubular cells: 64.6;Oligodendrocyte precursor cells: 371.5;Oligodendrocytes: 134.7" "Cancer enriched" "Detected in some" 18 "glioma: 116.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 12.1;eosinophil: 37.6" "Lineage enriched" "Detected in many" 15 "granulocytes: 37.6" "Group enriched" "Detected in some" 6 "NB-4: 39.2;RPMI-8226: 20.8;THP-1: 25.5;U-937: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 24: NB-4 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (4.13e-2)" "unprognostic (6.46e-2)" "unprognostic (4.06e-1)" "unprognostic (3.58e-1)" "unprognostic (9.01e-3)" "unprognostic (2.40e-1)" "unprognostic (7.93e-2)" "unprognostic (1.50e-1)" "unprognostic (3.82e-3)" "unprognostic (5.19e-2)" "unprognostic (8.17e-2)" "unprognostic (2.51e-1)" "unprognostic (4.05e-2)" "unprognostic (5.96e-3)" "unprognostic (3.20e-2)" "unprognostic (1.17e-1)" 0.0 0.0 126.5 0.1 168.1 0.8 0.0 132.7 127.3 0.0 34.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 103.6 121.3 2.8 0.1 0.7 0.0 154.2 156.5 0.0 0.1 0.0 0.5 0.0 128.1 0.0 0.0 0.0 0.2 0.0 1.3 0.8 0.1 0.0 118.4 0.6 0.2 2.0 144.5 0.0 0.0 0.6 0.0 0.1 0.0 178.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 2.6 0.7 0.0 0.0 0.0 0.0 1.8 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 39.2 0.2 0.0 0.0 0.0 0.1 20.8 0.0 0.0 1.3 0.0 0.0 0.0 4.7 0.0 0.2 25.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 29.1 1.6 12.1 2.4 37.6 0.0 0.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 2.5 0.1 0.0 0.6 126.5 168.1 132.7 127.3 103.6 121.3 154.2 156.5 128.1 118.4 144.5 178.0 0.0 0.0 0.0 13.7 0.3 0.0 0.1 0.0 0.0 0.0 0.9 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.6 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 1.8 0.0 0.0 3.2 0.0 0.5 0.0 2.4 5.4 1.0 24.1 0.0 1.0 371.5 134.7 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.4 0.0 2.7 3.3 0.0 0.1 0.1 0.1 0.0 0.0 0.1 OLIG3 "Bhlhb7, bHLHe20" ENSG00000177468 "Oligodendrocyte transcription factor 3" Q7RTU3 6 137492199-137494394 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018303, CAB024865" Uncertain NA NA "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "CAB024865: , HPA018303: AB_1854796" "unprognostic (1.07e-3)" "unprognostic (1.44e-1)" "unprognostic (2.77e-1)" "unprognostic (2.03e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 OPRPN "BPLP, PRL1, PROL1" ENSG00000171199 "Opiorphin prepropeptide" Q99935 4 70397931-70410195 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 146.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 12.5;Breast myoepithelial cells: 3.3;Glandular and luminal cells: 2.1" "Group enriched" "Detected in some" 5 "breast cancer: 7.4;liver cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA065711 Approved "Secreted in other tissues" NA NA 63000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: Glandular cells - Unknown function" "HPA065711: AB_2685541" "unprognostic (3.11e-3)" "unprognostic (2.22e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 146.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 OR10V1 ENSG00000172289 "Olfactory receptor family 10 subfamily V member 1" Q8NGI7 11 59712916-59713845 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA060076 Uncertain NA NA "HPA060076: AB_2684198" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ORAI1 "CRACM1, FLJ14466, TMEM142A" ENSG00000276045 "ORAI calcium release-activated calcium modulator 1" Q96D31 12 121626550-121642677 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 60.1" "Cell type enhanced" "Detected in many" "dendritic cells: 92.3;NK-cells: 88.6;Theca cells: 86.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 81.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016583 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA016583: AB_1848720" "unprognostic (2.22e-2)" "unprognostic (3.78e-3)" "unprognostic (7.82e-3)" "unprognostic (8.83e-2)" "unprognostic (3.20e-1)" "unprognostic (1.99e-3)" "unprognostic (4.25e-3)" "unprognostic (1.92e-1)" "unprognostic (2.00e-2)" "prognostic favorable (4.30e-4)" "unprognostic (1.41e-1)" "unprognostic (2.59e-1)" "unprognostic (6.84e-2)" "unprognostic (1.95e-1)" "unprognostic (1.83e-1)" "unprognostic (2.04e-1)" "unprognostic (1.57e-2)" 10.8 5.4 4.4 9.6 4.6 8.8 10.9 5.2 6.8 7.3 22.1 10.6 20.8 7.6 0.0 8.7 7.7 3.3 9.3 3.8 4.9 11.2 12.3 15.5 12.0 5.5 4.9 6.7 8.1 8.7 2.6 4.5 5.5 6.4 0.3 0.0 15.6 2.6 60.1 46.6 13.8 2.2 5.4 23.1 12.5 11.5 5.1 6.1 10.4 14.0 2.8 11.1 7.8 5.1 18.3 42.0 3.4 16.9 4.0 4.9 18.4 20.5 2.9 8.8 4.7 33.1 16.2 13.3 31.4 3.1 11.8 30.2 3.4 13.7 0.0 41.9 7.8 23.9 6.8 16.6 10.1 18.5 43.7 2.0 5.1 14.4 0.9 4.9 12.9 30.0 16.8 6.9 2.3 41.4 46.1 81.7 19.6 10.3 35.7 16.8 7.9 20.5 5.0 13.4 16.4 3.3 10.7 11.7 17.5 0.2 29.3 11.6 23.5 21.0 8.4 28.6 15.9 9.4 8.7 5.6 15.7 25.9 19.1 9.4 6.3 8.2 18.6 5.4 13.9 6.3 15.4 18.8 7.5 9.0 14.3 12.5 6.9 7.5 5.2 1.9 13.7 7.6 4.4 4.6 5.2 6.8 3.8 4.9 5.5 4.9 5.5 5.4 5.1 5.1 32.0 28.9 16.4 1.0 41.0 22.6 10.1 3.4 6.8 2.1 48.4 22.9 4.2 18.6 10.3 1.8 4.2 3.7 92.3 8.4 1.9 13.3 3.4 14.1 11.1 40.6 2.4 23.8 0.3 19.5 15.2 9.5 8.6 17.4 7.0 24.0 43.2 17.9 38.6 0.0 0.5 9.3 2.0 28.2 65.0 11.8 13.4 42.8 21.4 4.7 27.2 5.8 88.6 3.0 1.5 29.5 6.3 9.4 30.5 14.8 17.2 12.1 6.3 6.9 0.0 6.3 10.8 1.7 6.0 6.9 37.4 7.8 70.3 86.0 20.1 10.7 ORC6 ORC6L ENSG00000091651 "Origin recognition complex subunit 6" Q9Y5N6 16 46689643-46698394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;lymphoid tissue: 7.4;testis: 9.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 56.7;Spermatocytes: 102.6;Spermatogonia: 108.9;Theca cells: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016330, HPA072587" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 24: B-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB016330: AB_670295, HPA072587: AB_2686537" "unprognostic (3.47e-2)" "unprognostic (8.99e-3)" "unprognostic (2.92e-1)" "unprognostic (4.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.19e-2)" "unprognostic (3.15e-6)" "unprognostic (1.36e-2)" "prognostic unfavorable (3.53e-4)" "prognostic favorable (1.48e-4)" "unprognostic (1.50e-4)" "unprognostic (3.97e-2)" "unprognostic (3.90e-14)" "unprognostic (2.08e-1)" "unprognostic (4.24e-1)" "unprognostic (2.79e-1)" "unprognostic (5.98e-2)" 0.3 0.7 2.0 2.2 1.6 10.3 0.6 1.5 1.9 0.7 1.0 1.7 1.5 0.8 1.1 4.1 0.4 0.6 1.5 1.9 1.8 0.4 0.9 0.6 7.4 1.5 1.9 0.4 0.3 0.7 0.6 3.3 1.7 0.3 1.9 0.3 0.7 0.2 0.1 1.1 1.5 1.0 1.6 2.4 0.8 9.6 1.8 6.2 0.5 0.3 7.3 1.2 1.3 1.8 28.6 27.4 43.7 33.9 5.4 6.8 31.6 54.2 20.2 59.3 30.9 39.3 18.0 35.6 27.1 10.5 29.1 29.9 57.9 15.1 50.4 17.2 46.4 27.9 13.2 40.1 6.6 46.5 23.7 1.8 2.6 32.4 17.1 9.3 20.0 30.1 36.0 17.4 35.9 26.9 65.6 60.7 48.1 20.7 76.0 78.6 80.6 35.8 14.9 9.8 52.2 30.4 24.5 29.8 18.1 34.9 15.6 37.9 11.6 53.7 34.6 33.6 51.8 12.5 18.9 123.2 22.2 29.5 40.1 0.0 0.3 0.3 0.9 0.7 0.4 0.7 0.5 0.5 0.6 1.4 0.8 0.3 0.0 0.8 0.8 1.0 1.2 0.7 2.0 1.6 1.5 1.9 1.9 1.8 1.5 1.9 1.7 1.6 1.8 1.8 1.6 3.2 14.5 1.0 8.8 6.6 2.2 3.6 8.6 6.6 4.1 5.8 3.7 1.5 6.3 5.5 4.2 39.3 6.0 9.5 1.9 2.5 13.2 6.5 7.5 4.3 1.8 45.4 6.3 0.7 40.9 8.0 7.1 9.4 1.3 56.7 0.7 9.9 15.7 11.8 2.7 12.4 6.1 3.8 11.9 8.9 2.8 7.7 33.8 2.8 1.2 2.5 2.1 0.0 2.0 2.1 1.4 3.4 18.5 2.6 2.3 1.0 10.7 10.2 0.0 5.1 7.3 102.6 108.9 16.9 6.0 10.9 7.5 47.5 14.4 2.7 OSBP OSBP1 ENSG00000110048 "Oxysterol binding protein" P22059 11 59574398-59615774 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039227, HPA043625" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 70000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039227: AB_2676401, HPA043625: AB_2678587" "unprognostic (3.09e-2)" "unprognostic (3.76e-2)" "prognostic favorable (2.08e-5)" "unprognostic (7.80e-3)" "unprognostic (7.32e-2)" "unprognostic (2.79e-2)" "unprognostic (2.13e-1)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (7.42e-2)" "unprognostic (1.42e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.08e-7)" "unprognostic (1.25e-1)" "unprognostic (9.00e-2)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" 19.6 41.7 14.1 15.5 15.2 27.2 27.4 15.3 18.9 24.7 18.4 26.8 29.4 20.0 31.6 19.6 22.4 19.5 25.5 15.0 15.6 42.8 57.6 18.5 17.8 15.4 16.7 22.4 37.3 44.9 16.1 22.9 16.7 25.9 28.3 15.9 30.1 27.0 57.7 26.6 25.5 21.2 14.0 15.6 27.8 18.0 15.7 24.0 32.3 43.8 23.7 19.6 17.1 15.1 40.9 33.6 24.7 33.2 56.5 52.4 26.8 32.9 42.3 38.4 34.4 38.1 40.2 41.1 42.7 37.9 47.2 41.4 45.4 43.5 43.0 40.0 20.9 28.1 25.1 25.8 60.2 36.2 52.9 40.4 52.8 36.2 94.4 40.0 41.7 38.3 48.6 37.3 34.5 19.0 34.0 26.2 28.0 59.5 32.7 32.5 39.8 28.6 45.6 47.0 28.5 20.3 38.6 47.7 46.0 33.6 66.9 22.7 45.8 32.7 22.8 49.5 22.3 51.9 45.2 41.4 37.0 25.6 26.8 1.7 1.6 1.5 2.8 1.4 2.6 2.2 2.9 2.3 1.6 1.6 2.6 2.1 1.5 2.2 1.3 4.0 1.3 1.1 14.1 15.2 15.3 18.9 15.0 15.6 15.4 16.7 16.7 14.0 15.7 15.1 29.2 25.6 9.0 14.7 18.9 39.6 16.4 13.7 29.6 23.8 38.0 27.1 34.1 32.9 19.0 27.6 22.9 14.2 31.1 34.0 7.9 14.0 8.8 37.9 52.7 21.8 30.0 10.5 25.6 18.6 14.7 21.1 22.4 43.8 27.9 21.8 15.4 67.1 16.0 26.9 22.9 40.0 8.2 12.9 16.9 14.5 15.8 17.9 14.2 12.2 9.6 15.7 18.6 18.1 23.3 20.2 20.5 19.9 32.2 31.2 34.6 21.0 27.8 21.7 6.6 28.4 19.3 25.1 14.5 27.0 47.3 30.8 20.0 43.5 28.4 26.4 OSBPL2 "DFNA67, KIAA0772, ORP-2" ENSG00000130703 "Oxysterol binding protein like 2" Q9H1P3 20 62231922-62296213 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid transport, Transport" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 94.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 94.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041127, HPA042659" Uncertain Approved Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA041127: AB_10962008, HPA042659: AB_10960683" "unprognostic (1.00e-3)" "unprognostic (7.20e-3)" "unprognostic (1.31e-1)" "unprognostic (6.00e-2)" "unprognostic (1.82e-1)" "unprognostic (1.73e-3)" "unprognostic (3.79e-2)" "unprognostic (9.60e-2)" "unprognostic (6.22e-2)" "unprognostic (1.50e-1)" "unprognostic (1.73e-1)" "unprognostic (6.82e-3)" "prognostic favorable (4.20e-5)" "unprognostic (3.86e-2)" "unprognostic (8.13e-2)" "unprognostic (4.00e-1)" "unprognostic (3.32e-2)" 14.6 15.2 21.1 13.4 21.2 32.9 18.9 38.9 21.4 21.9 20.0 24.3 22.8 14.0 15.8 40.7 15.6 20.0 25.4 16.6 20.3 20.8 18.0 16.2 14.3 23.7 24.0 15.8 39.7 26.4 26.4 13.7 22.3 19.8 22.7 14.5 24.9 18.8 18.0 43.5 21.6 17.4 19.4 24.9 27.9 14.9 29.8 17.2 21.9 11.9 20.4 23.1 29.8 19.4 23.9 17.0 19.6 18.3 19.4 19.1 18.5 14.2 27.9 46.6 32.1 61.0 24.1 11.5 37.1 28.4 41.8 40.7 18.9 42.4 25.7 13.7 17.7 30.6 21.5 31.2 19.0 11.8 26.6 17.7 61.0 20.8 23.3 22.1 19.1 29.4 20.3 21.2 13.5 19.4 17.2 19.8 6.4 43.5 15.0 15.9 23.5 15.3 23.6 48.2 25.6 16.7 25.7 48.2 24.3 25.9 32.1 21.0 13.2 23.2 17.0 24.7 17.3 24.5 37.4 17.5 25.7 8.4 14.9 16.1 9.2 34.5 13.0 11.7 11.4 13.7 10.5 13.7 9.9 10.9 9.5 11.4 94.6 16.8 9.9 7.1 17.5 10.9 21.1 21.2 38.9 21.4 16.6 20.3 23.7 24.0 22.3 19.4 29.8 19.4 27.1 16.0 18.3 17.3 16.5 20.1 24.8 24.4 14.2 18.9 24.7 16.6 61.2 15.7 28.2 11.0 6.2 13.4 21.6 44.5 31.3 22.7 33.0 22.6 12.0 18.1 16.3 24.2 13.9 20.1 14.8 17.8 42.8 34.2 10.8 19.2 12.8 14.1 12.3 18.5 21.7 29.6 22.4 11.1 8.0 17.4 17.4 14.3 8.8 10.3 16.8 18.2 27.8 9.0 15.5 39.8 37.0 13.2 21.9 38.8 30.2 14.1 34.3 15.9 13.1 14.8 13.1 22.8 11.1 25.2 27.8 37.1 18.5 12.0 25.7 58.7 OSBPL6 ORP6 ENSG00000079156 "Oxysterol binding protein like 6" Q9BZF3 2 178194481-178402893 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.8;tongue: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 281.4;Excitatory neurons: 314.2;Inhibitory neurons: 404.2;Oligodendrocyte precursor cells: 134.2" "Cancer enhanced" "Detected in many" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 48.8;hTERT-HME1: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032131 Enhanced Approved "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA032131: AB_10670963" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "unprognostic (2.47e-1)" "unprognostic (5.95e-3)" "unprognostic (5.26e-2)" "unprognostic (1.40e-2)" "unprognostic (7.55e-2)" "unprognostic (4.81e-2)" "unprognostic (3.32e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.49e-2)" "unprognostic (1.15e-5)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (3.73e-4)" "unprognostic (4.44e-6)" 1.3 1.5 4.1 1.0 6.1 0.2 1.7 3.7 16.3 1.1 0.0 1.0 0.7 0.8 0.7 2.4 1.0 1.1 3.8 6.1 8.0 2.7 5.6 4.0 1.1 5.7 6.9 1.4 1.2 0.8 6.7 0.6 5.3 3.1 1.0 8.4 2.2 1.5 33.8 8.7 3.5 1.4 1.7 1.0 0.8 1.3 7.5 1.6 2.3 20.3 0.8 1.0 1.5 8.3 0.0 1.1 8.3 16.9 6.8 7.5 6.3 13.9 7.2 12.0 14.6 1.4 0.2 0.0 0.5 12.9 6.6 0.3 19.6 11.4 20.2 0.2 10.2 48.8 2.9 0.0 4.4 8.0 0.3 5.0 17.6 26.4 50.8 4.3 5.8 6.2 0.9 5.8 15.9 7.0 0.1 0.0 10.0 0.0 10.2 0.0 16.9 3.2 0.9 0.0 6.3 3.8 6.2 1.8 13.7 9.2 2.4 0.1 11.4 13.7 8.5 9.3 16.3 31.8 13.4 0.0 16.3 0.0 6.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 4.1 6.1 3.7 16.3 6.1 8.0 5.7 6.9 5.3 1.7 7.5 8.3 0.7 0.0 7.2 281.4 0.0 13.3 2.1 1.3 7.4 59.4 2.1 1.7 15.2 4.3 6.5 0.0 25.0 0.2 0.0 0.1 1.9 0.6 1.0 4.4 1.0 1.7 1.8 0.0 314.2 0.8 4.9 4.3 0.0 0.4 7.0 2.0 0.0 6.2 3.9 1.7 404.2 6.0 4.1 3.5 1.0 1.1 0.0 0.7 5.4 62.8 0.0 10.6 0.0 134.2 10.3 0.2 0.0 1.5 1.5 2.2 9.5 6.2 78.2 6.9 0.0 25.4 5.8 0.1 2.1 6.4 20.9 0.1 0.9 14.5 1.4 0.5 OSR1 ODD ENSG00000143867 "Odd-skipped related transcription factor 1" Q8TAX0 2 19351485-19358623 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 81.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 35.8;Leydig cells: 133.6;Peritubular cells: 45.9;Smooth muscle cells: 21.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.9" "Region enhanced" "Detected in some" "thalamus: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 11 "U-2197: 101.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015525 Uncertain NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA015525: AB_1854822" "unprognostic (1.71e-3)" "unprognostic (1.23e-1)" "unprognostic (6.85e-4)" "unprognostic (1.42e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-2)" "unprognostic (8.47e-4)" "unprognostic (2.79e-1)" "unprognostic (1.91e-1)" "unprognostic (6.87e-2)" "unprognostic (3.56e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-3)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (1.62e-1)" 38.6 2.4 0.4 3.5 0.8 0.0 22.4 0.3 1.7 16.7 1.8 23.1 1.4 10.3 0.3 3.6 8.1 5.9 13.4 1.6 0.0 1.5 0.5 17.0 0.5 0.3 0.1 6.1 2.8 0.2 2.7 3.3 0.2 13.9 2.0 0.0 31.5 3.7 3.0 10.8 11.1 11.3 0.2 0.1 9.7 5.4 3.4 0.6 10.2 3.5 0.1 81.4 12.3 0.0 0.0 2.4 0.1 4.7 3.2 9.2 0.0 6.0 2.8 5.6 2.8 0.0 0.1 0.0 0.0 8.5 2.7 0.0 3.0 1.4 1.4 0.0 0.2 0.0 0.1 3.5 4.0 0.0 0.2 4.6 0.0 5.2 6.9 4.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.1 0.0 3.6 5.0 0.0 0.2 0.0 0.6 1.9 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 1.3 0.4 101.8 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.3 1.7 1.6 0.0 0.3 0.1 0.2 0.2 3.4 0.0 1.2 0.0 0.5 0.0 0.0 4.7 1.0 1.7 0.6 0.0 1.0 6.1 7.2 0.0 1.1 3.7 0.0 0.5 0.1 0.1 0.0 1.3 0.7 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.4 35.8 0.0 0.1 1.3 1.2 0.0 0.0 0.9 0.0 0.0 0.3 4.1 0.0 4.9 3.8 133.6 0.3 3.6 2.8 0.0 0.0 0.0 0.0 0.1 0.4 0.1 45.9 0.0 0.4 0.0 2.9 0.3 0.0 0.0 1.3 21.4 0.4 0.1 0.3 4.1 0.4 0.7 0.8 0.2 1.1 OSR2 FLJ90037 ENSG00000164920 "Odd-skipped related transciption factor 2" Q8N2R0 8 98944403-98952104 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 166.1;endometrium 1: 155.1;fallopian tube: 155.3" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 243.1;Leydig cells: 784.1;Peritubular cells: 758.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 16 "ASC diff: 542.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052425, HPA063486" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA052425: AB_2681826, HPA063486: AB_2685022" "unprognostic (1.72e-1)" "unprognostic (1.92e-3)" "unprognostic (1.03e-1)" "unprognostic (5.94e-2)" "unprognostic (1.57e-1)" "prognostic favorable (2.44e-5)" "unprognostic (1.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.89e-2)" "unprognostic (3.73e-3)" "unprognostic (3.01e-2)" "unprognostic (6.19e-2)" "unprognostic (1.57e-7)" "unprognostic (1.37e-2)" "unprognostic (2.39e-1)" "unprognostic (2.56e-4)" "unprognostic (8.54e-3)" 45.0 9.9 0.0 2.4 0.0 0.6 26.0 0.2 0.2 166.1 0.0 9.2 0.6 155.1 53.7 15.1 155.3 12.9 4.2 0.0 0.0 1.3 0.3 3.6 2.4 0.0 0.0 93.2 4.2 3.0 2.7 8.2 0.0 40.2 3.8 0.0 6.8 72.2 5.6 27.9 24.9 47.1 0.0 0.2 5.1 35.6 0.0 0.8 5.6 5.1 1.1 27.2 83.8 0.0 32.3 4.5 0.0 4.4 542.4 17.2 4.3 17.6 33.1 13.7 13.6 3.4 3.9 0.0 2.9 26.7 0.8 12.4 2.7 4.7 6.7 1.5 13.0 0.6 3.3 1.6 8.9 0.9 0.6 17.0 9.8 2.3 1.6 0.8 0.0 4.8 4.0 0.4 0.6 14.6 2.9 5.7 0.0 2.6 2.8 13.8 1.6 1.1 1.1 2.7 1.4 0.1 1.9 7.5 0.4 0.3 4.3 7.5 0.2 2.1 0.1 13.9 1.0 0.7 0.5 0.3 0.9 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.9 14.1 6.6 3.4 1.2 0.0 7.9 5.3 0.7 0.0 3.3 0.0 0.0 17.2 0.9 0.7 0.0 0.0 5.8 7.8 243.1 3.7 0.0 0.0 0.0 0.0 138.4 71.7 0.5 5.9 0.0 0.2 0.0 0.0 9.3 0.0 0.0 18.4 10.2 1.9 21.9 24.1 784.1 2.7 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 758.3 4.6 3.6 103.9 0.1 1.7 0.0 32.9 8.8 21.3 5.1 4.5 0.3 9.1 24.2 2.3 95.6 22.3 2.2 OSTF1 "bA235O14.1, OSF, SH3P2" ENSG00000134996 "Osteoclast stimulating factor 1" Q92882 9 75088514-75147265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 329.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 302.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020514 Approved Supported Cytosol NA NA 580000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA020514: AB_2670461" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (7.54e-2)" "prognostic favorable (3.67e-5)" "unprognostic (1.36e-1)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (1.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-3)" "unprognostic (3.76e-1)" "unprognostic (7.89e-2)" "unprognostic (6.36e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" 44.3 36.9 27.8 65.7 35.0 56.3 34.9 32.0 37.2 34.1 25.4 42.5 38.2 22.7 38.2 104.8 20.0 42.8 32.0 28.3 33.2 34.6 57.7 56.4 74.9 31.0 32.5 16.0 19.4 72.1 19.1 69.9 33.1 22.7 45.8 12.3 38.5 19.6 9.5 63.1 47.8 28.8 30.8 87.0 40.6 18.0 31.0 47.8 29.0 16.0 85.0 55.3 53.9 35.1 69.1 16.0 7.7 11.2 45.4 41.7 81.3 71.9 46.9 26.9 24.4 8.2 50.8 70.9 35.3 59.2 34.6 111.8 12.9 51.9 77.0 302.0 16.0 39.3 24.8 42.5 36.7 71.5 141.6 29.1 49.2 31.6 21.8 23.7 91.2 59.4 13.4 158.4 65.4 35.9 107.5 44.8 14.5 161.5 30.8 20.1 52.3 63.0 57.0 97.1 6.5 0.6 53.1 74.1 36.2 58.2 97.4 79.9 86.4 55.8 19.4 108.3 30.8 30.1 52.5 26.7 67.1 81.9 46.4 359.5 177.7 464.8 158.6 199.3 169.6 101.2 110.5 131.5 148.7 87.4 62.1 109.8 495.2 168.4 256.8 110.6 163.0 283.0 27.8 35.0 32.0 37.2 28.3 33.2 31.0 32.5 33.1 30.8 31.0 35.1 113.4 22.4 24.4 8.1 90.8 82.2 61.2 78.2 61.5 2.9 38.6 23.2 7.8 28.6 51.2 33.1 6.2 125.5 162.1 64.8 76.3 49.7 11.9 42.8 59.4 60.5 27.2 23.3 32.0 52.3 252.9 42.1 31.1 51.1 137.6 4.2 71.7 32.2 233.1 10.1 12.6 31.9 69.2 167.4 181.5 6.0 23.9 155.7 76.5 43.1 329.9 6.0 268.8 30.2 67.3 60.5 97.7 15.4 83.2 34.1 64.1 63.0 27.3 8.6 19.7 15.9 45.0 6.7 17.8 141.4 114.5 133.9 163.8 37.6 38.2 91.6 OTOGL "C12orf64, FLJ90579" ENSG00000165899 "Otogelin like" Q3ZCN5 12 80099537-80380880 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 1.9;kidney: 5.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 51.2;Oligodendrocyte precursor cells: 42.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.3;U-87 MG: 2.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "basal ganglia: 4.2" "HPA040364, HPA053392" Uncertain Approved Cytosol "Secreted in other tissues" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA040364: AB_10795365, HPA053392: AB_2682135" "unprognostic (2.43e-1)" "unprognostic (2.78e-2)" "unprognostic (2.55e-2)" "unprognostic (1.50e-1)" "unprognostic (5.99e-2)" "unprognostic (3.10e-1)" "unprognostic (3.34e-3)" "unprognostic (4.76e-2)" "unprognostic (2.72e-2)" "unprognostic (4.52e-2)" "unprognostic (2.79e-2)" "unprognostic (1.57e-1)" "unprognostic (1.95e-5)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.79e-2)" "unprognostic (2.04e-2)" 0.1 0.0 0.5 0.0 0.7 0.0 0.1 0.0 1.0 0.1 0.0 0.4 0.0 0.1 0.1 0.1 0.1 0.1 1.9 0.3 0.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.5 0.1 0.1 0.1 0.5 0.0 0.1 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.3 0.0 0.0 2.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 1.4 0.1 0.1 0.2 0.0 0.0 51.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.9 0.0 0.0 0.0 42.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 OTUD1 "DUBA7, OTDC1" ENSG00000165312 "OTU deubiquitinase 1" Q5VV17 10 23439075-23442377 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 149.0;Langerhans cells: 219.1;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 38.1;HaCaT: 36.5;SiHa: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038503, HPA038504" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA038503: AB_2676049, HPA038504: AB_10672712" "unprognostic (1.84e-1)" "unprognostic (2.80e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.56e-1)" "unprognostic (1.29e-2)" "unprognostic (3.18e-3)" "unprognostic (2.41e-1)" "unprognostic (7.77e-2)" "unprognostic (4.10e-2)" "unprognostic (1.80e-2)" "unprognostic (1.32e-1)" "prognostic favorable (6.61e-7)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (3.66e-1)" "unprognostic (1.43e-2)" 13.0 11.7 8.0 10.2 8.4 60.4 10.3 9.5 10.2 8.4 8.4 8.7 6.8 10.2 6.8 7.8 11.2 9.7 43.4 8.7 9.0 19.7 7.6 19.7 14.4 8.3 8.0 13.6 6.9 19.4 8.0 12.1 7.6 8.8 7.6 5.9 6.7 7.6 29.4 20.9 8.2 9.4 8.4 13.7 22.9 7.5 9.2 6.8 13.3 22.6 12.5 11.9 7.6 9.2 4.8 2.3 2.4 1.1 9.3 4.6 3.2 1.9 4.2 4.4 4.0 0.9 38.1 2.2 4.1 2.4 1.5 36.5 2.5 4.5 2.9 17.4 7.1 0.1 5.7 1.5 8.0 0.4 3.2 4.8 19.4 1.3 6.1 3.9 1.5 2.2 0.5 15.1 2.5 2.3 1.5 1.4 1.9 2.7 1.3 2.4 10.8 2.2 5.8 4.0 1.1 2.6 23.4 4.1 11.3 6.3 1.7 3.3 2.7 2.5 3.7 7.0 0.8 7.6 15.0 1.1 3.8 1.5 1.0 2.5 0.5 1.0 0.3 0.6 0.3 0.7 0.5 0.3 0.3 1.2 0.4 0.6 1.3 0.0 1.9 0.2 1.3 0.2 8.0 8.4 9.5 10.2 8.7 9.0 8.3 8.0 7.6 8.4 9.2 9.2 17.3 67.3 11.5 3.3 55.9 32.0 7.1 5.0 13.6 20.1 12.3 9.1 149.0 7.2 4.9 5.5 2.1 3.3 9.6 47.2 11.7 6.0 8.0 35.0 44.5 25.6 6.0 13.5 4.3 7.1 3.2 20.8 47.4 33.8 5.7 10.4 16.4 10.1 51.0 53.8 4.8 77.9 10.2 68.2 219.1 7.6 6.5 105.7 33.8 8.4 9.3 33.8 10.3 4.0 6.5 10.1 16.3 13.2 50.0 7.7 8.0 25.1 9.8 26.2 6.6 82.2 19.4 7.2 4.7 15.1 30.5 7.9 16.5 7.5 24.3 10.9 OTULIN "FAM105B, FLJ34884" ENSG00000154124 "OTU deubiquitinase with linear linkage specificity" Q96BN8 5 14664664-14699850 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.8" "Cell type enhanced" "Detected in many" "dendritic cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051074 Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Plasma membrane" "HPA051074: AB_2681334" "unprognostic (4.81e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (1.19e-2)" "unprognostic (7.48e-2)" "unprognostic (1.91e-2)" "unprognostic (7.94e-3)" "unprognostic (1.43e-1)" "unprognostic (2.48e-2)" "unprognostic (9.55e-2)" "unprognostic (1.02e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.59e-7)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (5.02e-2)" 5.0 3.9 4.8 9.6 6.3 26.8 4.6 5.9 4.9 5.5 6.2 4.7 7.6 3.6 2.6 8.0 3.5 4.7 6.7 4.9 5.0 4.4 12.3 6.4 12.5 6.6 5.6 4.8 6.8 3.8 3.6 6.5 6.4 6.3 4.6 4.6 5.7 3.3 5.2 11.8 5.8 4.8 5.6 7.1 4.3 7.1 5.8 11.2 4.1 5.5 13.5 5.7 6.9 7.1 10.0 11.5 11.2 12.8 10.0 10.3 12.3 9.8 6.9 13.8 10.2 15.4 7.2 18.0 18.9 6.4 19.9 11.1 14.1 12.9 9.2 31.1 11.6 12.9 36.3 8.3 8.8 12.4 21.2 6.0 15.2 11.3 9.4 7.6 11.8 14.9 13.0 27.8 10.0 6.1 12.4 10.6 6.9 10.5 12.0 18.8 10.0 7.1 8.9 10.1 5.1 8.3 35.1 7.8 7.6 13.5 8.5 14.1 11.1 17.8 20.0 13.4 13.2 12.4 20.6 20.3 10.1 23.2 9.3 0.2 0.6 1.1 0.3 0.7 1.0 0.3 0.8 1.1 1.0 1.6 0.5 1.3 0.7 0.3 1.1 0.8 1.7 0.3 4.8 6.3 5.9 4.9 4.9 5.0 6.6 5.6 6.4 5.6 5.8 7.1 20.3 3.2 11.5 23.5 24.6 0.0 23.2 0.0 26.2 11.9 12.8 11.7 15.0 10.0 4.3 5.5 14.6 15.1 70.6 21.1 7.9 5.5 9.4 20.6 28.1 13.3 9.5 13.7 18.5 5.8 10.3 10.1 16.8 24.0 10.2 14.0 6.4 36.9 13.9 8.4 19.5 15.7 0.0 18.9 0.0 4.2 10.5 25.0 0.0 38.4 17.1 10.4 26.8 16.6 31.7 8.0 13.3 6.4 38.5 25.9 14.1 15.1 5.1 31.4 0.0 11.5 10.2 29.7 28.8 23.7 0.0 14.2 35.8 7.6 15.6 23.1 OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "Extravillous trophoblasts: 49.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "myeloid DC: 1.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 7 "dendritic cells: 2.1" "Cell line enhanced" "Detected in some" "RT4: 3.3;SK-BR-3: 1.4;U-2 OS: 1.6" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" 1.3 0.0 1.0 1.3 0.8 0.1 4.2 0.5 1.5 1.0 0.5 2.0 0.2 0.5 2.5 2.1 1.6 0.1 0.2 0.8 2.1 4.0 0.0 0.4 0.1 1.2 1.3 0.1 0.5 0.3 0.3 0.9 1.0 0.5 1.6 0.0 3.0 0.4 0.2 2.6 0.4 0.5 0.7 0.4 0.2 0.1 2.6 0.3 0.5 0.3 0.8 1.7 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.1 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 1.0 0.8 0.5 1.5 0.8 2.1 1.2 1.3 1.0 0.7 2.6 1.3 0.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 1.7 1.4 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.2 1.9 0.0 0.2 0.7 0.1 0.8 1.2 0.0 0.6 0.0 49.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.6 0.5 0.0 0.0 0.4 0.1 0.0 0.3 3.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.9 0.0 0.0 2.2 0.0 3.7 0.0 0.0 1.2 0.0 P2RX1 P2X1 ENSG00000108405 "Purinergic receptor P2X 1" P51575 17 3896592-3916476 "Predicted membrane proteins" "Apoptosis, Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.0;pancreas: 65.1;urinary bladder: 75.5" "Cell type enriched" "Detected in some" 5 "granulocytes: 185.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 46.3" "Group enriched" "Detected in many" 30 "dendritic cells: 15.1;granulocytes: 23.5;monocytes: 46.3" "Cell line enhanced" "Detected in some" "HEL: 13.8;HMC-1: 8.4;Karpas-707: 16.8;THP-1: 14.7;U-937: 7.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.3" HPA057678 Approved "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Endoplasmic reticulum" "HPA057678: " "unprognostic (1.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.65e-1)" "unprognostic (3.54e-2)" "unprognostic (7.34e-3)" "unprognostic (9.89e-5)" "unprognostic (1.77e-2)" "unprognostic (6.15e-3)" "unprognostic (2.98e-1)" "unprognostic (2.52e-3)" "unprognostic (1.90e-1)" "unprognostic (2.20e-2)" "unprognostic (4.47e-3)" "unprognostic (2.60e-1)" "unprognostic (5.58e-2)" "unprognostic (4.29e-1)" "unprognostic (1.09e-2)" 9.8 2.0 0.5 4.4 0.8 42.0 1.5 0.8 0.7 7.7 0.4 13.4 9.3 7.3 1.8 23.0 3.9 2.0 2.0 0.5 0.7 1.0 0.7 4.8 2.9 0.8 0.9 2.1 65.1 0.1 0.3 3.8 0.8 10.7 9.2 0.1 1.6 34.1 0.5 5.9 9.0 6.0 0.7 13.0 2.8 2.6 0.6 2.0 0.4 0.3 3.2 75.5 8.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.2 0.1 1.1 1.8 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.1 3.3 0.0 0.4 0.0 2.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.1 7.4 0.0 0.0 10.8 11.9 0.0 20.4 0.0 0.4 0.0 0.0 5.9 0.9 0.0 0.0 23.5 0.0 46.3 15.1 0.0 8.2 0.5 0.8 0.8 0.7 0.5 0.7 0.8 0.9 0.8 0.7 0.6 1.0 0.1 3.2 4.2 0.7 15.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.0 0.1 8.9 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 18.5 0.3 2.0 0.1 0.9 0.5 0.0 185.4 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.0 5.1 2.4 0.2 0.0 22.5 0.0 1.0 7.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 36.0 0.0 0.0 0.1 0.7 0.0 0.0 0.4 3.4 0.0 0.1 0.1 0.9 0.0 1.8 0.5 0.3 0.0 P2RX7 "MGC20089, P2X7" ENSG00000089041 "Purinergic receptor P2X 7" Q99572 12 121132819-121188032 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.8;Oligodendrocyte precursor cells: 87.9;Oligodendrocytes: 156.7" "Group enriched" "Detected in all" 5 "glioma: 7.2;melanoma: 19.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 2.9;gdT-cell: 1.3;intermediate monocyte: 4.5;myeloid DC: 2.6;non-classical monocyte: 3.3;T-reg: 1.4" "Group enriched" "Detected in many" 5 "dendritic cells: 2.6;monocytes: 4.5;T-cells: 1.4" "Cell line enhanced" "Detected in many" "Karpas-707: 40.0;RPMI-8226: 24.8;SK-MEL-30: 41.0;U-266/70: 21.7;U-266/84: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034968, HPA042013, HPA044141" Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA034968: AB_10673105, HPA042013: AB_2677797, HPA044141: AB_2678830" "unprognostic (1.05e-1)" "unprognostic (4.90e-2)" "unprognostic (8.87e-2)" "unprognostic (6.54e-3)" "unprognostic (4.49e-2)" "unprognostic (1.55e-2)" "unprognostic (8.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.05e-2)" "unprognostic (1.08e-1)" "unprognostic (2.42e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.91e-1)" "unprognostic (3.59e-2)" "unprognostic (5.55e-2)" "unprognostic (1.65e-1)" 2.8 2.5 20.2 5.1 28.5 2.9 2.0 23.1 30.7 6.1 11.3 3.6 1.5 4.1 1.5 1.4 2.3 3.5 1.3 21.8 20.7 0.7 4.6 6.5 5.9 26.3 24.7 8.3 1.4 1.7 1.8 2.9 28.3 1.8 2.3 0.5 2.5 1.8 0.6 13.1 1.8 4.2 21.3 5.9 1.6 1.3 26.2 1.7 1.0 1.0 3.6 2.3 4.4 47.3 0.1 0.0 0.0 1.0 1.1 0.4 0.8 0.1 1.9 0.7 1.7 0.0 0.0 0.1 0.1 0.7 4.3 0.2 0.0 0.0 0.5 1.8 0.1 0.7 0.0 0.1 0.8 1.6 11.6 1.0 0.0 2.0 0.0 0.0 1.9 0.4 0.0 40.0 0.0 0.0 0.2 4.4 0.1 0.0 0.4 3.8 8.9 24.8 0.0 0.0 0.5 2.3 0.2 0.0 41.0 0.0 0.6 7.8 0.0 0.6 0.1 0.1 0.2 21.7 20.2 0.1 2.4 11.8 6.1 0.4 2.9 0.0 1.3 4.5 0.5 0.3 0.6 0.6 2.6 0.2 0.5 0.6 0.3 0.6 3.3 0.4 1.4 0.9 20.2 28.5 23.1 30.7 21.8 20.7 26.3 24.7 28.3 21.3 26.2 47.3 2.0 3.2 4.8 12.1 3.9 6.9 3.0 0.0 1.8 3.9 1.8 2.2 2.4 5.7 3.7 0.0 2.1 3.5 9.0 1.2 0.0 1.2 0.6 0.7 1.6 3.9 0.0 1.7 52.8 0.0 0.9 3.7 0.0 0.3 6.3 2.6 5.3 3.9 23.4 1.7 18.4 0.2 0.0 21.5 35.0 1.5 11.1 34.2 16.0 34.7 21.2 1.3 7.2 87.9 156.7 0.2 0.0 10.5 1.3 1.2 0.1 0.0 3.6 1.0 6.6 3.2 1.9 1.2 0.9 1.0 3.7 4.0 6.6 4.1 0.1 1.0 P2RY1 "P2Y1, SARCC" ENSG00000169860 "Purinergic receptor P2Y1" P47900 3 152835131-152841439 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 25.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.3;Cholangiocytes: 21.5;Distal enterocytes: 25.4;Kupffer cells: 21.1;Squamous epithelial cells: 45.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.0;non-classical monocyte: 2.6" "Group enriched" "Detected in many" 9 "granulocytes: 6.0;monocytes: 2.6" "Cell line enriched" "Detected in many" 5 "HEL: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015577 Enhanced NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "HPA015577: AB_1854882" "unprognostic (3.30e-1)" "unprognostic (4.52e-2)" "unprognostic (2.68e-2)" "unprognostic (4.76e-2)" "unprognostic (9.70e-2)" "unprognostic (1.40e-3)" "unprognostic (3.32e-2)" "unprognostic (2.53e-1)" "unprognostic (5.14e-1)" "unprognostic (2.58e-1)" "unprognostic (4.68e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (2.04e-7)" "unprognostic (1.36e-1)" "unprognostic (8.98e-2)" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" 1.6 1.4 6.2 2.3 14.2 5.7 1.4 3.1 6.4 4.5 1.0 9.1 3.2 6.5 0.5 19.2 2.1 2.0 2.9 5.9 6.7 0.8 1.5 7.0 0.8 3.3 4.2 8.8 3.3 0.3 1.6 25.4 8.4 7.7 6.7 9.0 3.2 2.2 7.7 8.9 6.1 4.5 4.9 2.2 0.9 1.1 8.2 1.6 1.3 3.4 2.7 2.4 8.0 4.1 0.0 0.7 7.0 0.0 1.1 0.1 0.0 0.0 0.1 0.2 0.6 9.0 0.1 0.0 0.7 0.0 1.1 1.5 3.9 1.3 0.3 0.0 3.4 45.9 0.1 0.0 0.0 5.4 4.0 0.5 8.7 0.0 0.4 3.5 0.0 1.5 1.4 0.0 0.0 0.1 0.8 0.1 6.4 0.0 5.5 0.0 0.2 1.3 0.0 3.1 1.1 0.0 0.0 0.0 0.9 1.6 0.0 2.4 0.0 0.7 1.8 0.0 3.9 0.0 0.0 0.0 4.5 0.0 5.2 6.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.1 6.2 14.2 3.1 6.4 5.9 6.7 3.3 4.2 8.4 4.9 8.2 4.1 1.0 0.0 0.5 12.7 0.8 1.9 6.7 3.3 15.9 23.3 0.5 0.1 7.1 21.5 1.0 0.0 0.0 0.2 1.6 25.4 0.0 1.3 0.2 1.9 12.0 7.1 0.0 10.8 0.0 0.0 0.3 5.6 0.0 2.7 10.1 0.1 11.7 0.3 7.4 0.0 0.2 8.9 0.0 21.1 0.3 0.8 14.9 15.9 0.0 1.0 1.8 19.1 0.0 0.0 0.6 0.9 12.3 6.0 0.0 6.3 13.4 0.2 0.2 1.5 0.0 1.2 1.0 0.4 2.2 45.4 2.0 0.1 0.5 3.5 8.3 4.9 PAAF1 "FLJ11848, Rpn14, WDR71" ENSG00000175575 "Proteasomal ATPase associated factor 1" Q9BRP4 11 73876699-73931114 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 130.1" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 112.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039952, HPA040020" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA039952: AB_10793925, HPA040020: AB_2676802" "unprognostic (3.13e-1)" "unprognostic (1.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-1)" "unprognostic (2.05e-1)" "unprognostic (2.13e-2)" "unprognostic (4.51e-2)" "unprognostic (1.33e-1)" "unprognostic (4.58e-3)" "unprognostic (1.74e-1)" "unprognostic (4.48e-1)" "unprognostic (2.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.23e-1)" "unprognostic (2.73e-1)" "unprognostic (4.42e-1)" 17.3 29.0 85.2 11.3 92.6 9.0 17.6 82.3 130.1 19.4 68.8 25.0 11.8 16.6 23.8 14.4 19.6 12.0 25.2 80.3 85.9 23.9 21.9 12.6 12.6 88.0 88.6 24.6 22.2 19.1 25.8 11.7 87.3 22.0 16.3 46.4 15.4 19.8 19.8 19.2 14.3 15.5 85.4 16.3 18.5 30.3 85.7 15.9 18.8 7.5 17.2 21.7 16.3 101.2 13.5 30.6 27.2 21.3 28.9 29.6 15.5 22.6 25.9 35.3 25.0 60.2 10.4 40.4 34.4 23.2 32.8 30.2 33.5 27.2 52.2 30.4 20.8 41.4 28.0 50.3 34.6 39.1 15.3 30.5 41.7 38.8 47.2 28.4 27.0 32.1 50.7 33.7 33.2 26.3 34.5 40.5 12.7 71.0 23.7 31.6 72.6 66.5 26.5 22.9 28.8 33.8 26.8 17.7 70.6 25.4 53.1 21.8 19.7 24.8 15.7 35.3 22.3 41.3 50.3 82.2 17.4 25.0 26.5 53.4 26.2 32.3 26.8 17.2 29.5 40.8 28.7 27.3 34.4 36.1 37.0 31.7 2.2 32.4 6.3 24.8 36.8 27.9 85.2 92.6 82.3 130.1 80.3 85.9 88.0 88.6 87.3 85.4 85.7 101.2 9.0 3.2 12.5 40.1 11.5 4.7 11.6 27.3 6.8 50.4 6.8 9.1 19.6 8.6 15.6 16.5 112.6 33.5 9.5 5.5 13.7 15.9 38.4 10.7 12.2 9.8 3.6 20.2 17.4 13.8 4.8 11.5 6.6 9.4 19.6 30.1 11.7 13.6 18.8 47.1 23.7 7.7 20.3 9.5 6.6 22.6 16.8 9.5 14.2 14.0 16.3 37.6 18.6 24.6 55.5 7.3 5.7 18.0 15.3 9.6 12.0 53.5 14.1 51.7 6.6 18.2 12.5 48.9 28.6 9.6 8.1 18.3 9.8 29.9 10.3 8.0 PABPC1L2B RBM32B ENSG00000184388 "Poly(A) binding protein cytoplasmic 1 like 2B" Q5JQF8 X 73002939-73006106 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.2;pituitary gland: 2.1;prostate: 2.7;salivary gland: 2.1;testis: 1.6" "Cell type enhanced" "Detected in some" "Early spermatids: 1.7;Excitatory neurons: 2.2;Inhibitory neurons: 2.7;Oligodendrocytes: 1.7" "Cancer enriched" "Detected in single" 23 "prostate cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.1" HPA041573 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA041573: AB_2677556" "unprognostic (1.73e-1)" "unprognostic (2.26e-1)" "unprognostic (3.31e-1)" 0.0 0.6 2.6 0.0 1.7 0.0 0.0 0.2 5.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.3 3.4 0.0 0.0 0.0 0.0 1.6 1.0 0.0 0.0 0.0 2.1 0.0 0.8 2.7 0.0 0.4 2.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 0.2 5.2 1.3 3.4 1.6 1.0 0.8 0.1 2.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PABPC4L ENSG00000254535 "Poly(A) binding protein cytoplasmic 4 like" P0CB38 4 134196333-134201789 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 10.3" "Cell type enhanced" "Detected in some" "Adipocytes: 5.3;Endometrial ciliated cells: 7.4;Endometrial stromal cells: 5.7;Fibroblasts: 5.5;Glandular and luminal cells: 12.2;Leydig cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 11.4;HeLa: 15.8;REH: 8.1;RH-30: 8.5;U-2 OS: 8.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 20: HeLa - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.00e-1)" "unprognostic (3.53e-2)" "unprognostic (1.96e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (2.55e-3)" "unprognostic (1.58e-1)" "unprognostic (3.63e-1)" "unprognostic (9.05e-3)" "unprognostic (2.97e-1)" "unprognostic (9.52e-2)" "unprognostic (6.44e-2)" "prognostic favorable (1.11e-5)" "unprognostic (4.41e-3)" "unprognostic (1.82e-1)" "unprognostic (1.22e-1)" "unprognostic (4.14e-3)" 1.5 0.4 0.6 0.5 0.7 0.0 0.8 0.5 0.8 2.4 0.5 0.4 0.3 3.7 1.4 0.7 2.0 1.1 1.7 0.4 0.5 1.0 0.1 0.5 0.2 0.5 0.5 2.2 0.3 5.3 0.3 10.3 0.6 2.9 0.3 0.0 2.1 4.2 0.2 0.3 0.3 2.4 0.5 0.1 0.3 0.5 1.1 0.9 2.0 0.9 0.5 0.7 0.8 0.6 0.0 0.1 2.8 0.0 0.0 0.0 0.0 3.4 2.3 1.6 1.9 0.0 0.0 0.0 3.5 0.0 0.0 0.3 11.4 0.1 2.3 0.0 2.6 4.5 15.8 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.6 0.0 2.3 0.0 1.3 0.0 0.1 0.0 0.0 0.0 1.4 8.1 8.5 0.0 0.5 0.0 3.4 0.9 0.0 0.7 0.2 2.9 0.0 1.5 0.2 2.9 8.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.8 0.4 0.5 0.5 0.5 0.6 0.5 1.1 0.6 5.3 3.2 1.1 0.0 0.0 0.3 0.4 0.0 1.2 0.0 0.2 0.9 1.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.3 7.4 5.7 4.3 0.0 0.0 0.0 0.0 0.4 5.5 0.0 12.2 0.0 3.8 1.8 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 2.3 5.6 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 1.4 3.1 1.3 0.8 0.1 0.8 0.3 4.5 0.0 0.1 PACSIN1 SDPI ENSG00000124507 "Protein kinase C and casein kinase substrate in neurons 1" Q9BY11 6 34466061-34535229 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 149.3;retina: 64.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 76.1;Cone photoreceptor cells: 81.3;dendritic cells: 24.9;Excitatory neurons: 49.9;Horizontal cells: 69.0;Inhibitory neurons: 47.6;Rod photoreceptor cells: 89.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.8" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.8" "Cell line enhanced" "Detected in some" "MCF7: 12.1;RPMI-8226: 14.0;T-47d: 21.5;U-266/84: 16.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009929, HPA028852, HPA055491" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" "CAB009929: AB_2268057, HPA028852: AB_10602812, HPA055491: AB_2682834" "unprognostic (3.33e-1)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.72e-2)" "unprognostic (2.47e-3)" "unprognostic (2.14e-2)" "unprognostic (2.65e-1)" "unprognostic (1.74e-1)" "unprognostic (6.63e-2)" "unprognostic (3.95e-4)" "unprognostic (9.12e-2)" "unprognostic (3.02e-2)" "unprognostic (4.18e-2)" "unprognostic (9.90e-2)" "unprognostic (5.50e-2)" "unprognostic (9.33e-2)" 0.2 0.7 40.9 1.2 72.9 0.8 0.2 0.0 149.3 0.3 0.0 0.8 0.5 0.5 0.1 0.1 0.6 0.3 5.4 64.4 0.0 1.4 0.2 0.2 3.6 58.8 10.0 0.6 5.1 1.7 6.3 0.0 55.4 0.7 0.2 64.3 1.0 0.4 0.2 0.3 1.4 0.1 0.0 1.3 1.3 0.8 3.9 1.3 0.2 0.1 2.2 0.4 0.3 59.5 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 4.5 0.8 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 1.1 0.1 0.0 12.1 0.7 0.0 2.8 0.1 0.1 0.1 0.0 14.0 0.0 0.4 4.2 0.3 0.0 2.2 0.0 0.4 21.5 2.4 0.0 0.0 0.3 0.0 0.0 3.5 16.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.6 0.0 15.8 0.0 0.1 40.9 72.9 0.0 149.3 64.4 0.0 58.8 10.0 55.4 0.0 3.9 59.5 0.2 0.0 0.0 2.3 0.3 0.0 0.1 0.0 0.0 76.1 0.2 0.1 4.5 0.0 0.0 0.0 81.3 0.1 24.9 0.1 0.0 0.3 0.2 1.3 0.2 0.6 0.0 0.0 49.9 0.7 0.0 0.1 0.5 2.0 0.0 0.2 0.0 0.0 0.0 69.0 47.6 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 6.5 0.0 12.7 1.0 1.0 2.0 0.1 0.0 0.0 0.2 0.1 0.0 2.3 0.0 89.4 0.0 0.2 0.2 0.4 1.7 0.0 0.0 0.0 0.6 0.1 0.1 0.1 PACSIN3 SDPIII ENSG00000165912 "Protein kinase C and casein kinase substrate in neurons 3" Q9UKS6 11 47177522-47186443 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 161.8;skeletal muscle: 480.9;tongue: 279.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 112.0;Extravillous trophoblasts: 60.6;Muller glia cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 127.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039480, HPA043904" Approved Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA039480: AB_2676531, HPA043904: AB_2678725" "unprognostic (1.75e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (6.89e-2)" "unprognostic (4.66e-2)" "unprognostic (8.17e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.09e-4)" "unprognostic (3.86e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-2)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" 14.4 66.5 19.6 4.5 28.2 0.4 18.4 24.5 20.9 33.3 18.8 50.2 4.7 33.5 11.4 52.6 29.1 7.2 161.8 18.0 19.4 14.8 43.6 15.9 2.0 33.8 27.5 23.2 33.1 11.0 6.2 16.1 32.1 35.2 2.7 4.5 40.8 20.6 480.9 41.4 11.3 21.2 25.0 4.5 33.5 4.5 25.4 2.0 24.5 279.4 5.2 21.5 31.8 39.0 56.4 27.1 12.5 51.5 10.3 10.2 59.8 19.4 24.6 33.9 19.1 40.8 7.3 0.3 5.9 9.2 23.0 90.0 23.7 40.2 13.0 8.7 44.8 8.4 105.5 91.7 19.9 2.0 8.4 28.2 52.3 17.9 28.3 27.2 15.3 15.2 18.4 0.7 13.9 106.7 0.7 40.8 15.5 43.7 58.7 33.1 48.0 9.0 14.3 49.3 0.3 42.6 28.2 17.9 24.6 24.6 127.3 6.9 6.9 57.6 62.5 7.5 47.1 10.1 4.4 5.3 18.6 19.2 30.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 19.6 28.2 24.5 20.9 18.0 19.4 33.8 27.5 32.1 25.0 25.4 39.0 6.1 0.0 8.1 4.9 0.3 35.9 29.1 25.1 30.7 0.7 32.2 24.3 112.0 38.6 18.1 5.5 0.0 31.0 0.6 0.2 9.8 37.7 0.0 3.1 8.4 7.8 0.0 2.7 0.8 15.5 60.6 12.6 9.7 6.2 0.0 3.0 8.6 33.1 6.0 0.0 1.1 0.2 14.2 1.6 4.6 0.4 16.1 1.0 17.8 2.8 0.0 63.6 0.0 0.0 9.5 41.0 0.0 12.4 2.6 56.8 1.5 24.3 5.0 3.2 32.9 18.5 25.4 0.2 7.5 39.7 29.8 18.3 0.7 4.8 1.4 29.8 PADI2 "KIAA0994, PDI2" ENSG00000117115 "Peptidyl arginine deiminase 2" Q9Y2J8 1 17066761-17119451 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 240.6;skeletal muscle: 311.8;tongue: 492.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 95.9;Distal enterocytes: 178.7;Intestinal goblet cells: 77.3;Oligodendrocytes: 117.1;Paneth cells: 72.3" "Cancer enhanced" "Detected in many" "glioma: 24.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 43.3;neutrophil: 100.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 100.6" "Cell line enhanced" "Detected in some" "A549: 11.6;RPTEC TERT1: 33.1;SK-BR-3: 50.7;T-47d: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047735 Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA047735: AB_2680139" "unprognostic (2.61e-2)" "unprognostic (3.60e-2)" "unprognostic (8.94e-3)" "unprognostic (1.57e-1)" "unprognostic (2.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.49e-1)" "unprognostic (3.74e-3)" "unprognostic (2.78e-3)" "unprognostic (3.28e-3)" "unprognostic (1.29e-1)" "unprognostic (3.07e-1)" "unprognostic (2.87e-1)" "unprognostic (3.64e-2)" "unprognostic (3.15e-1)" "unprognostic (2.27e-1)" "unprognostic (5.91e-3)" 2.1 0.9 85.9 9.3 161.5 23.7 41.1 164.3 103.9 3.3 33.5 89.8 1.4 0.8 0.6 6.1 2.7 1.6 0.6 82.2 165.1 12.7 0.7 4.4 1.0 205.8 167.0 0.2 1.5 2.1 3.7 1.4 212.0 2.6 92.3 50.5 44.4 1.6 311.8 9.6 8.4 5.8 189.3 13.4 2.2 0.8 144.3 2.1 0.6 492.3 1.3 2.5 1.0 240.6 0.0 11.6 0.1 0.0 0.0 0.0 0.7 0.3 0.0 0.1 0.1 0.1 4.9 0.2 1.5 0.5 0.1 1.6 0.4 0.1 0.3 0.0 0.8 0.5 0.0 0.0 0.0 0.7 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.9 3.8 0.6 1.4 1.6 3.9 0.0 0.0 0.0 0.4 33.1 0.0 2.1 0.2 0.0 50.7 0.0 2.7 13.9 2.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.9 0.0 1.3 16.2 43.3 0.0 0.9 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 100.6 0.0 0.2 0.4 0.0 6.4 85.9 161.5 164.3 103.9 82.2 165.1 205.8 167.0 212.0 189.3 144.3 240.6 0.2 0.0 1.3 28.4 1.0 0.3 0.4 0.6 0.0 2.2 31.2 32.5 0.4 0.0 3.3 1.8 95.9 0.2 0.7 178.7 11.7 0.6 6.1 0.0 0.0 8.2 3.6 0.0 1.5 0.0 0.5 0.6 0.0 0.1 17.1 0.5 0.7 0.0 7.2 0.0 1.4 77.3 2.0 4.8 25.8 10.3 0.3 9.2 28.4 15.9 33.8 33.6 0.0 13.6 117.1 0.0 72.3 0.7 0.4 0.5 15.0 0.3 0.2 29.6 0.0 5.6 1.3 0.2 0.4 0.0 0.4 0.1 0.4 0.0 51.8 0.2 PADI4 "PAD, PADI5, PDI4, PDI5" ENSG00000159339 "Peptidyl arginine deiminase 4" Q9UM07 1 17308195-17364004 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "bone marrow: 105.1;lymphoid tissue: 29.9" "Cell type enhanced" "Detected in some" "dendritic cells: 8.3;granulocytes: 12.6;Macrophages: 14.6;monocytes: 22.3;NK-cells: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "basophil: 79.9;classical monocyte: 71.3;eosinophil: 97.5;neutrophil: 183.0" "Group enriched" "Detected in all" 9 "granulocytes: 183.0;monocytes: 71.3" "Cell line enhanced" "Detected in some" "HEL: 1.2;RPMI-8226: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017007, HPA042825" Enhanced NA NA 29000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA017007: AB_1854921, HPA042825: AB_2678189" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (1.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-2)" "unprognostic (8.49e-2)" "unprognostic (5.22e-2)" "unprognostic (8.55e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" 1.8 0.1 0.2 0.7 0.4 105.1 0.3 0.2 0.8 0.1 0.2 0.1 0.1 0.1 0.0 0.4 1.0 0.4 1.1 0.3 0.2 0.5 1.7 7.9 0.3 0.3 0.1 0.1 0.3 0.0 0.2 0.5 0.3 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.4 0.0 29.9 0.4 0.1 0.1 1.6 0.3 0.3 0.2 0.7 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 79.9 71.3 97.5 0.4 5.7 0.2 1.1 0.5 0.7 13.9 1.8 2.6 4.5 183.0 4.5 1.8 6.2 0.4 35.8 0.2 0.4 0.2 0.8 0.3 0.2 0.3 0.1 0.3 0.0 0.1 0.4 0.0 0.0 3.7 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.6 0.6 0.0 0.0 12.6 0.1 0.0 0.4 0.2 0.0 0.4 0.0 0.0 3.3 0.4 0.2 0.0 14.6 0.0 0.0 22.3 0.0 20.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 4.0 0.0 0.0 0.1 2.3 0.1 0.0 0.0 PAEP "GD, GdA, GdF, GdS, MGC138509, MGC142288, PAEG, PEP, PP14" ENSG00000122133 "Progestagen associated endometrial protein" P09466 9 135561756-135566955 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 94.1;endometrium 1: 256.0" "Cell type enriched" "Detected in some" 10 "Glandular and luminal cells: 10785.5" "Cancer enriched" "Detected in many" 8 "melanoma: 275.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 3.1;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.1" "Cell line enriched" "Detected in some" 7 "SK-MEL-30: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016762, HPA020108, HPA029473" Enhanced "Secreted in female reproductive system" NA NA 120000 "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "CAB016762: , HPA020108: AB_1855595, HPA029473: AB_10610147" "unprognostic (3.39e-2)" "unprognostic (8.47e-3)" "unprognostic (6.84e-2)" "unprognostic (3.46e-2)" "unprognostic (3.20e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (1.27e-2)" "unprognostic (1.72e-1)" "unprognostic (3.95e-3)" "unprognostic (1.93e-3)" "prognostic unfavorable (0.00e+0)" "prognostic unfavorable (5.46e-4)" "unprognostic (4.24e-1)" "unprognostic (4.98e-2)" 0.1 0.2 0.2 1.1 0.4 1.6 0.5 0.7 0.7 94.1 2.0 0.1 1.0 256.0 0.9 0.2 4.8 0.3 0.1 0.4 0.4 0.1 0.1 0.5 0.6 0.3 0.2 0.7 0.0 0.0 0.0 27.2 0.2 2.7 0.1 0.4 0.4 44.8 0.6 2.1 0.8 0.1 0.1 0.3 6.0 0.7 0.4 0.0 0.3 0.0 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.0 0.9 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.6 1.6 2.2 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.2 2.9 0.2 0.0 0.3 0.0 0.7 0.5 0.0 0.0 0.2 0.2 0.3 0.0 0.2 0.4 0.2 0.1 0.2 21.0 0.6 0.3 0.2 0.0 0.0 1.0 0.2 0.1 0.8 2.2 0.1 0.2 0.2 0.2 3.1 0.3 0.2 0.2 0.2 0.1 0.2 0.3 0.2 0.1 0.4 0.3 0.3 1.4 0.3 0.3 0.5 0.1 0.1 0.2 0.4 0.7 0.7 0.4 0.4 0.3 0.2 0.2 0.1 0.4 1.0 0.0 0.0 0.5 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.9 0.6 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 613.5 1008.8 67.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 10785.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 144.0 0.0 0.0 0.0 0.0 0.0 86.5 0.0 0.0 0.0 PAIP2B KIAA1155 ENSG00000124374 "Poly(A) binding protein interacting protein 2B" Q9ULR5 2 71182738-71227103 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 181.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.0;Early spermatids: 95.1;Hepatocytes: 67.1;Proximal tubular cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 15.8;SCLC-21H: 23.1" "Low region specificity" "Detected in all" "HPA046784, HPA072371" Approved Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA046784: AB_2679804, HPA072371: AB_2686514" "unprognostic (8.70e-2)" "unprognostic (8.20e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.17e-5)" "unprognostic (4.56e-2)" "unprognostic (1.34e-1)" "unprognostic (9.67e-3)" "unprognostic (1.51e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.96e-12)" "unprognostic (1.63e-2)" "unprognostic (3.87e-1)" "unprognostic (1.21e-2)" "unprognostic (4.61e-2)" 2.4 1.6 131.5 1.8 159.1 1.3 4.5 108.3 176.8 3.1 66.3 3.8 3.7 2.9 1.8 6.1 7.2 1.1 23.0 94.7 116.5 10.3 18.1 2.7 2.1 134.9 136.6 11.5 54.2 6.0 2.2 0.6 143.0 4.8 3.7 27.7 37.9 3.5 48.5 16.4 2.7 1.7 132.8 2.2 10.5 2.2 130.3 2.4 11.6 26.7 4.6 2.8 4.0 181.5 2.5 0.6 1.0 3.6 0.4 0.5 4.4 0.3 0.1 0.3 0.2 0.9 1.0 3.2 0.6 0.0 2.4 2.0 6.1 3.7 1.2 1.7 5.0 3.1 0.4 0.1 1.6 0.8 0.2 0.6 3.3 0.2 3.6 0.9 0.6 7.2 5.5 3.0 0.2 3.2 1.0 1.7 2.6 5.8 2.3 0.0 10.5 15.8 1.9 1.7 23.1 1.3 2.6 1.7 1.1 5.5 7.5 0.2 0.1 0.3 1.9 1.9 1.0 6.1 5.5 3.9 0.2 1.1 0.5 0.5 0.3 0.5 1.0 0.4 1.2 2.5 1.3 1.0 0.4 2.6 2.1 1.9 0.2 0.8 0.4 2.3 0.6 0.6 131.5 159.1 108.3 176.8 94.7 116.5 134.9 136.6 143.0 132.8 130.3 181.5 3.3 3.2 4.5 5.2 9.9 7.8 7.0 4.0 5.7 11.3 14.8 8.8 86.0 12.8 2.7 7.3 6.2 3.2 13.2 2.7 21.5 4.9 95.1 18.4 3.9 3.9 41.5 15.6 4.2 41.3 9.2 4.7 11.2 17.5 1.3 7.5 7.1 67.1 1.9 6.7 4.6 6.3 14.2 3.2 1.6 30.0 5.3 2.6 14.2 2.8 2.4 12.3 4.1 2.5 31.9 10.4 4.0 5.3 29.9 9.4 1.3 56.9 15.5 43.3 0.0 9.3 4.0 32.9 7.7 17.3 20.0 6.3 4.7 4.3 8.1 6.0 PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40217428-40277487 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 25.6;skin 1: 28.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;NK-cells: 16.5;Suprabasal keratinocytes: 19.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 26.5;HaCaT: 32.2;hTCEpi: 19.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031124 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: AB_10601044" "unprognostic (1.85e-3)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (7.79e-3)" "unprognostic (7.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (1.34e-2)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (8.87e-3)" "unprognostic (1.72e-1)" "unprognostic (1.79e-1)" "unprognostic (7.37e-3)" "unprognostic (3.34e-2)" 0.2 8.2 11.6 0.4 15.9 0.9 2.1 8.5 16.6 4.5 0.0 1.3 1.5 0.9 1.0 25.6 4.3 1.1 8.3 17.6 3.0 4.7 0.3 2.5 0.9 1.4 1.1 0.6 8.0 8.0 12.1 7.6 1.9 4.4 1.1 0.8 6.1 3.8 4.5 28.2 1.5 0.3 1.8 0.9 3.9 17.7 3.0 0.5 7.5 1.3 1.9 3.5 9.4 5.4 3.9 0.0 0.2 0.0 0.0 0.0 6.0 0.0 0.2 0.7 0.7 26.5 2.9 0.1 3.6 0.0 1.3 32.2 4.5 6.9 0.3 0.2 1.0 0.0 3.0 0.2 0.0 0.1 0.3 0.0 19.4 0.3 4.5 0.2 0.0 5.5 1.8 0.3 0.0 4.5 0.0 0.5 0.5 3.9 2.9 0.2 0.2 2.9 1.5 8.4 7.3 2.0 2.6 10.9 0.3 1.7 1.7 10.3 0.0 0.3 0.6 0.0 0.3 0.1 0.3 0.1 0.7 0.6 0.2 1.2 0.1 1.2 2.3 0.1 0.8 0.6 0.1 1.9 0.3 0.1 0.1 0.4 0.5 0.9 0.1 0.1 0.0 0.6 11.6 15.9 8.5 16.6 17.6 3.0 1.4 1.1 1.9 1.8 3.0 5.4 0.0 0.0 4.2 0.7 0.3 9.8 9.6 4.8 8.6 3.5 2.8 2.9 0.0 4.3 5.4 5.5 0.0 52.7 2.1 0.3 13.7 4.4 8.6 3.3 0.4 0.3 4.9 0.0 8.9 4.3 3.0 0.7 0.5 5.1 0.0 0.7 0.0 0.0 4.1 0.0 7.3 1.1 2.0 0.6 0.9 5.8 1.8 0.3 1.8 1.0 0.0 1.3 16.5 0.5 0.3 2.5 1.0 1.9 0.1 5.2 0.2 0.2 3.9 0.2 0.0 0.3 0.4 1.9 3.3 13.9 19.0 9.0 1.0 0.8 2.0 11.3 PALLD "CGI-151, KIAA0992, SIH002" ENSG00000129116 "Palladin, cytoskeletal associated protein" Q8WX93 4 168497052-168928457 "Disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 527.9;Cardiomyocytes: 591.7;Peritubular cells: 399.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 304.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035905, CAB070159" Enhanced Supported "Plasma membrane,Actin filaments,Mitochondria,Cytosol" No No 27000 "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "Plasma membrane, Mitochondria, Cytosol" "CAB070159: AB_1726016, HPA035905: AB_2674854" "unprognostic (3.59e-2)" "unprognostic (3.99e-1)" "unprognostic (2.55e-2)" "unprognostic (5.03e-3)" "unprognostic (2.51e-1)" "unprognostic (7.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.40e-2)" "unprognostic (3.57e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (3.86e-1)" "unprognostic (8.54e-2)" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.28e-4)" 65.0 35.5 31.7 49.7 27.3 0.9 43.6 11.1 19.9 146.1 0.0 303.3 29.0 301.5 21.9 122.6 118.4 71.0 180.4 27.9 36.2 42.1 12.4 71.7 16.9 29.8 25.9 62.1 13.2 55.6 11.3 62.1 25.1 137.0 74.9 12.8 40.8 205.7 127.7 34.7 64.1 303.1 21.4 60.5 94.8 35.1 24.7 23.3 38.7 47.3 16.6 280.2 85.3 22.7 82.1 39.6 87.9 53.4 77.2 83.9 123.6 53.7 137.6 47.2 66.7 1.1 4.6 36.6 14.4 23.7 29.0 17.0 54.1 138.8 60.5 73.9 16.6 0.8 112.5 10.4 135.5 0.4 1.0 132.8 84.4 85.5 125.4 115.0 20.8 19.7 0.1 0.5 304.5 3.8 23.8 1.4 24.9 20.8 24.1 8.3 81.4 0.8 5.3 16.4 9.0 46.4 102.8 8.1 7.3 151.2 48.6 0.5 64.4 50.3 192.1 20.7 90.1 47.8 0.7 1.7 41.6 1.0 14.2 13.7 3.1 0.0 4.6 1.8 0.2 0.1 0.5 2.4 2.1 0.1 0.6 1.6 0.7 0.6 1.2 0.2 0.8 1.8 31.7 27.3 11.1 19.9 27.9 36.2 29.8 25.9 25.1 21.4 24.7 22.7 22.7 32.1 9.4 167.8 1.5 93.6 527.9 56.8 76.8 6.0 46.0 107.9 591.7 20.0 58.7 44.1 18.8 52.1 8.1 20.9 1.9 27.6 133.1 52.8 181.2 27.7 44.8 0.8 27.8 51.3 115.6 130.5 59.7 51.0 52.6 21.0 47.8 11.2 24.5 26.9 108.4 30.7 18.3 28.9 23.8 146.4 130.1 36.7 23.2 16.9 52.9 55.1 17.5 182.4 6.5 83.0 18.6 399.4 2.6 167.6 9.8 23.4 85.2 4.0 177.5 115.4 227.8 81.0 7.6 34.1 49.3 22.3 9.2 13.4 29.3 113.0 PAQR7 "MPRA, mSR" ENSG00000182749 "Progestin and adipoQ receptor family member 7" Q86WK9 1 25861484-25875708 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1939.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 75.5;HaCaT: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046936 Approved Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA046936: AB_2679869" "unprognostic (1.12e-1)" "unprognostic (2.08e-2)" "unprognostic (8.03e-2)" "unprognostic (4.54e-3)" "unprognostic (1.32e-1)" "unprognostic (3.41e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.47e-1)" "unprognostic (4.59e-3)" "unprognostic (7.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "prognostic favorable (1.05e-5)" "unprognostic (1.60e-2)" "unprognostic (2.98e-2)" "unprognostic (1.15e-2)" "unprognostic (1.54e-2)" 5.5 23.9 8.5 4.4 8.4 5.1 5.2 7.5 8.6 11.9 10.0 6.4 20.9 11.1 28.2 17.7 20.0 7.8 3.3 7.9 10.1 35.3 7.4 5.6 4.3 9.6 10.2 35.3 6.6 13.7 6.7 21.4 9.4 7.9 2.9 1.5 5.3 24.3 3.0 31.4 18.9 9.5 9.2 10.2 8.1 46.2 10.6 3.5 5.1 1.9 4.9 13.6 13.5 9.4 30.7 6.0 5.8 18.9 7.1 14.8 20.4 19.9 17.5 19.2 17.0 9.8 75.5 0.3 13.6 19.2 6.3 62.6 3.2 33.0 11.4 12.1 3.4 25.6 8.4 12.1 12.0 0.4 3.1 14.9 43.3 13.7 10.2 16.9 7.5 2.8 2.8 2.1 14.4 7.0 0.2 1.9 9.3 3.1 10.3 2.1 0.6 3.8 39.3 22.9 3.1 11.5 32.1 40.7 14.8 7.9 11.6 4.6 8.1 3.1 9.7 10.2 5.4 0.4 0.4 1.3 14.5 0.7 6.6 5.4 7.3 15.7 1.4 13.9 1.4 4.0 0.8 1.0 7.6 1.7 1.3 1.9 3.7 3.4 17.5 0.8 0.2 1.4 8.5 8.4 7.5 8.6 7.9 10.1 9.6 10.2 9.4 9.2 10.6 9.4 4.9 0.0 3.1 11.4 2.2 18.1 4.3 4.6 4.6 2.1 9.4 9.5 1.9 17.2 5.1 77.3 0.0 52.8 1.3 0.7 21.5 5.6 350.9 23.4 11.5 5.9 4.8 0.0 11.9 13.9 12.3 7.8 0.5 9.0 7.0 4.6 10.4 5.5 11.0 3.3 11.2 2.2 0.0 10.3 14.9 1939.3 19.9 7.8 21.4 7.5 7.6 1.6 0.0 8.5 4.0 6.4 3.0 15.1 0.7 3.1 27.9 70.2 8.6 0.6 13.1 4.3 4.7 11.6 10.0 4.7 13.1 35.7 1.6 5.8 3.7 3.1 PARD6G "PAR-6G, PAR6gamma" ENSG00000178184 "Par-6 family cell polarity regulator gamma" Q9BYG4 18 80157232-80247514 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.6;Oligodendrocyte precursor cells: 25.6;Squamous epithelial cells: 25.3;Suprabasal keratinocytes: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 36.4;hTCEpi: 34.0;RT4: 27.9;U-2 OS: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047017 Uncertain Approved "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA047017: AB_2679904" "unprognostic (1.11e-1)" "unprognostic (4.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.40e-2)" "unprognostic (2.97e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.80e-1)" "unprognostic (9.96e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.09e-2)" "unprognostic (6.86e-3)" "unprognostic (9.65e-2)" "unprognostic (1.01e-1)" "unprognostic (4.85e-1)" "unprognostic (2.72e-1)" 3.4 1.7 5.8 1.4 5.7 0.6 5.3 3.8 7.9 9.6 6.8 6.0 1.8 6.5 2.7 18.0 6.2 3.3 2.9 9.3 7.8 7.0 3.5 2.9 2.5 6.3 5.8 6.2 2.1 2.1 3.8 5.5 5.5 5.7 2.0 1.8 4.5 5.9 1.9 38.1 3.0 5.4 4.6 2.0 2.7 2.1 8.3 5.3 18.0 1.0 4.3 5.6 12.0 5.9 3.0 4.3 17.7 13.4 0.6 0.7 12.9 3.3 0.7 2.9 0.4 1.2 1.2 0.0 1.4 1.5 5.1 13.4 6.4 19.2 2.8 0.5 5.7 0.2 3.5 10.4 0.8 4.0 36.4 5.7 34.0 0.3 1.8 2.2 1.4 4.2 1.4 0.8 4.3 5.0 3.6 0.4 5.3 1.4 5.2 0.1 11.7 1.5 0.5 27.9 7.4 7.7 4.1 2.2 20.0 8.6 2.6 3.4 1.1 5.9 28.8 2.2 1.6 0.9 1.2 0.3 1.9 0.9 11.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 5.7 3.8 7.9 9.3 7.8 6.3 5.8 5.5 4.6 8.3 5.9 3.3 3.2 0.6 7.5 0.7 39.6 13.7 11.0 18.8 1.3 4.1 10.3 2.8 1.5 2.3 3.7 0.0 0.6 9.7 0.4 0.0 0.4 0.5 9.8 10.1 8.2 0.0 0.0 6.5 0.2 9.5 4.1 0.5 3.3 0.0 3.1 10.8 1.5 0.8 0.0 8.5 0.7 8.2 0.9 6.5 0.7 1.8 0.8 12.4 15.9 0.0 2.0 0.0 25.6 4.8 0.8 0.0 1.9 3.6 6.6 0.0 7.6 2.6 2.5 19.7 1.9 13.6 1.5 6.0 25.3 63.9 0.4 8.0 2.0 0.6 13.4 PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9;Distal enterocytes: 398.3;Intestinal goblet cells: 109.7;Paneth cells: 132.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 44.6;Karpas-707: 44.9;U-266/70: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" 45.1 51.8 4.1 27.7 5.4 0.4 29.3 0.0 19.3 43.3 2.1 91.3 7.0 34.7 14.0 13.5 23.3 28.6 103.6 10.4 26.0 55.9 1.3 33.7 18.2 1.3 3.9 19.6 34.1 73.1 41.0 40.7 21.2 83.8 113.4 6.0 39.4 64.5 21.0 11.1 15.7 48.2 0.0 15.3 13.4 12.0 4.1 17.3 123.7 18.1 20.9 44.9 25.0 0.0 1.1 1.9 1.7 0.0 44.6 0.3 0.2 0.0 0.2 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.1 0.1 15.1 0.0 0.0 0.2 3.3 0.0 0.0 0.0 7.4 0.0 1.3 1.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 44.9 0.8 0.5 5.2 0.2 4.3 0.0 2.7 0.0 4.1 11.8 0.2 9.5 2.8 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.0 2.7 2.9 0.3 4.2 49.8 5.1 12.9 4.7 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.0 8.1 0.0 0.0 4.0 5.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 4.1 5.4 0.0 19.3 10.4 26.0 1.3 3.9 21.2 0.0 4.1 0.0 44.8 16.0 84.1 2.9 11.6 3.2 27.2 6.5 4.0 7.0 4.0 3.4 181.9 31.5 10.4 0.0 0.0 0.3 0.1 398.3 3.9 0.5 10.1 3.0 73.5 6.4 19.9 2.7 51.3 49.2 0.7 13.2 2.0 2.8 1.3 61.9 2.9 0.0 1.5 0.0 77.8 109.7 14.2 0.3 34.7 28.6 36.7 4.9 8.8 1.0 0.7 0.1 0.0 6.0 3.6 23.5 132.1 74.4 42.9 32.6 2.5 27.7 7.2 1.7 46.0 5.4 61.5 1.6 3.2 0.3 1.8 0.8 1.9 14.9 81.6 9.1 PARPBP "C12orf48, FLJ20641, PARI" ENSG00000185480 "PARP1 binding protein" Q9NWS1 12 102120183-102197520 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.3;lymphoid tissue: 7.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 20.0;Spermatogonia: 17.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039677 Approved Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA039677: AB_10673426" "unprognostic (7.84e-3)" "unprognostic (1.34e-2)" "unprognostic (4.54e-3)" "unprognostic (3.03e-2)" "unprognostic (1.84e-1)" "unprognostic (3.03e-1)" "unprognostic (1.30e-5)" "unprognostic (2.52e-3)" "prognostic unfavorable (3.17e-4)" "unprognostic (2.38e-1)" "unprognostic (3.95e-3)" "unprognostic (2.83e-1)" "unprognostic (5.61e-8)" "unprognostic (3.50e-3)" "unprognostic (2.34e-1)" "unprognostic (9.16e-3)" "unprognostic (6.14e-2)" 0.8 0.6 0.2 3.1 0.2 9.3 1.8 0.3 0.4 1.2 0.1 3.0 2.3 1.2 0.5 3.6 0.6 1.1 0.4 0.3 0.4 0.8 0.6 0.6 4.2 0.3 0.4 0.7 0.2 0.3 0.2 2.3 0.3 1.0 3.8 0.2 0.9 0.9 0.4 1.9 2.7 1.7 0.3 1.2 1.8 3.9 0.3 7.5 0.5 0.3 5.1 1.9 1.1 0.3 13.5 27.2 23.6 13.7 3.8 3.4 16.7 19.9 11.0 32.0 27.9 14.8 10.4 25.4 11.4 7.8 16.2 14.5 38.5 11.7 34.2 25.7 22.6 31.9 15.7 13.9 1.1 33.5 9.1 3.3 2.8 22.3 14.4 8.3 21.6 18.9 31.0 15.3 21.1 10.7 30.5 31.1 31.7 17.8 26.6 20.4 38.9 16.7 10.3 21.1 15.9 14.7 13.8 16.6 11.8 24.0 27.1 12.1 8.5 16.5 15.7 20.2 25.3 11.3 24.8 22.8 11.4 33.7 22.4 2.6 0.4 1.0 0.5 0.6 0.1 1.1 0.9 0.8 0.7 0.7 0.5 0.6 0.0 0.5 0.4 0.7 1.8 0.7 0.2 0.2 0.3 0.4 0.3 0.4 0.3 0.4 0.3 0.3 0.3 0.3 1.1 0.0 0.0 2.9 4.3 3.7 1.5 3.6 0.6 1.9 2.4 2.4 0.7 1.5 2.5 1.8 0.0 11.3 2.3 1.5 5.9 1.6 2.5 3.0 11.6 2.5 1.8 20.0 4.1 1.3 13.9 4.8 6.1 3.0 5.7 15.0 2.2 0.1 6.5 3.3 5.3 3.1 10.2 5.7 4.3 2.6 1.2 3.1 0.0 3.7 1.7 0.2 2.1 3.5 4.1 1.2 0.8 0.4 14.2 0.7 1.3 1.8 1.4 0.9 0.0 1.1 2.8 16.0 17.7 9.8 1.6 3.6 4.1 9.3 7.8 1.6 PARS2 DKFZp727A071 ENSG00000162396 "Prolyl-tRNA synthetase 2, mitochondrial" Q7L3T8 1 54756898-54764523 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 9.8;Early spermatids: 11.0;Spermatocytes: 10.5;Spermatogonia: 11.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028308, HPA028314, HPA028518" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" No No "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center, Mitochondria" "HPA028308: AB_2672553, HPA028314: AB_10603981, HPA028518: AB_2672653" "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "prognostic favorable (1.26e-5)" "unprognostic (1.93e-2)" "unprognostic (1.19e-2)" "unprognostic (1.79e-3)" "prognostic unfavorable (2.34e-4)" "unprognostic (6.48e-2)" "unprognostic (2.72e-1)" "unprognostic (1.14e-1)" "unprognostic (9.42e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.24e-6)" "unprognostic (2.72e-2)" "unprognostic (9.77e-2)" "unprognostic (1.73e-2)" "unprognostic (9.64e-2)" 1.3 2.9 2.5 1.9 3.0 0.2 2.7 2.8 3.1 2.7 3.0 4.0 2.7 2.5 3.2 2.7 4.4 1.6 3.0 2.6 2.6 4.2 3.4 1.4 2.0 2.5 2.7 4.8 2.3 4.7 2.1 2.5 2.7 2.3 3.6 2.0 3.3 2.8 4.4 2.9 2.1 2.0 2.7 1.8 2.5 4.8 2.7 2.6 2.9 5.5 2.4 2.1 2.0 3.0 4.4 7.2 4.6 6.0 5.5 4.6 10.3 3.7 4.5 6.4 4.6 8.3 2.8 7.7 5.6 3.3 9.3 6.9 8.3 5.8 4.7 5.0 7.5 7.4 4.0 6.2 8.5 4.3 2.5 5.0 8.8 8.3 7.4 5.5 4.8 8.4 13.2 1.0 4.9 4.6 6.1 5.7 10.6 8.3 9.1 4.6 9.0 9.0 5.4 3.2 4.7 4.8 5.3 6.9 9.7 8.7 3.9 5.5 2.6 4.8 4.9 6.8 4.7 7.3 6.6 3.0 3.6 5.1 2.8 1.2 5.3 4.5 4.8 7.7 5.9 4.9 5.3 5.3 7.3 5.5 7.8 5.3 0.5 7.4 10.7 5.9 8.2 5.0 2.5 3.0 2.8 3.1 2.6 2.6 2.5 2.7 2.7 2.7 2.7 3.0 0.6 0.0 1.1 0.3 1.0 0.6 0.9 2.0 1.8 2.6 1.3 1.9 1.5 2.8 1.8 0.0 0.0 7.0 0.2 2.4 9.8 4.5 11.0 1.1 1.4 0.8 0.0 0.0 0.9 2.8 3.9 1.3 1.5 0.6 0.0 2.9 0.0 2.3 3.1 5.0 1.1 2.8 0.0 1.2 0.3 6.8 3.7 0.8 0.0 2.8 1.1 3.2 0.0 0.5 1.6 1.9 1.5 3.0 0.3 1.8 1.5 6.5 1.0 1.9 0.0 1.3 1.1 10.5 11.5 2.0 1.0 3.3 0.7 5.1 3.5 0.8 PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 29 "B-cells: 91.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 9 "Daudi: 66.6;REH: 194.1;U-698: 87.1" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394, HPA068498" Enhanced Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center, Vesicles, Cytosol" "CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" 0.3 0.1 0.4 14.9 0.3 9.4 0.1 0.5 0.5 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.8 0.2 0.3 0.6 0.1 0.2 0.3 39.7 1.1 6.5 0.0 0.0 0.0 0.2 0.1 4.1 0.3 0.8 0.5 1.0 0.0 3.1 0.0 6.6 0.0 0.8 18.7 1.6 0.6 1.9 2.8 0.2 0.0 36.2 1.1 0.0 0.3 0.1 0.3 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 66.6 0.1 0.0 0.1 0.2 0.1 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 0.1 0.3 1.9 0.3 0.4 194.1 0.4 0.3 0.0 0.0 13.2 2.9 0.1 0.7 0.0 0.0 0.0 7.5 0.2 0.0 0.2 0.1 0.0 0.2 0.1 87.1 0.0 1.5 0.1 0.7 0.0 0.1 0.0 0.1 0.1 39.0 0.0 0.0 0.1 26.0 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.7 0.4 0.3 0.5 0.5 0.3 0.6 1.1 6.5 4.1 0.8 1.9 0.3 0.0 0.0 0.0 0.7 91.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.3 0.0 3.1 0.0 0.9 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.0 0.1 0.0 2.7 0.4 0.0 0.1 0.0 0.1 0.0 0.8 0.1 0.6 0.2 0.2 0.0 0.0 2.0 0.0 0.0 0.3 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809624-27838082 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 22.8;testis: 70.3" "Group enriched" "Detected in many" 5 "Early spermatids: 364.9;Spermatocytes: 436.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 282.8" "Group enriched" "Detected in many" 4 "basal ganglia: 4.7;white matter: 13.9" "Not detected" "Not detected" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 1.1 0.6 0.1 6.6 0.1 9.1 2.3 0.0 0.1 1.1 0.0 8.9 8.4 1.2 0.0 6.6 0.6 0.7 0.2 0.1 0.1 0.4 1.1 0.7 12.8 0.1 0.3 0.2 0.4 0.2 0.0 5.1 0.2 0.4 10.1 0.0 0.9 0.0 0.2 4.8 8.1 2.7 0.1 1.5 3.6 70.3 0.3 22.8 0.5 0.1 12.4 1.6 2.1 0.1 282.8 94.2 94.4 57.9 8.3 15.7 36.9 129.5 63.0 133.2 112.3 33.7 51.2 156.4 43.3 51.7 150.2 76.4 87.6 44.7 145.7 35.8 48.0 35.0 64.6 49.2 0.6 25.7 54.1 4.4 36.0 62.6 32.8 24.3 68.5 75.9 54.3 100.6 160.4 34.5 87.7 29.1 15.6 80.1 80.0 54.4 126.9 41.2 51.2 44.9 36.1 53.2 48.2 56.0 75.0 26.2 58.0 37.3 40.6 85.6 207.3 111.5 141.5 15.4 39.4 70.1 54.0 43.4 188.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.3 0.1 0.2 0.0 0.0 0.0 4.2 8.9 2.8 10.8 0.0 0.0 2.9 2.4 0.5 2.8 2.6 0.0 0.0 29.8 1.3 5.5 0.0 0.6 364.9 2.5 2.2 2.4 0.0 61.7 0.1 0.0 49.3 6.7 6.6 3.5 0.0 13.5 5.7 1.7 5.0 0.0 0.1 9.4 6.1 1.9 1.6 76.8 8.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 3.0 14.0 2.0 1.5 0.3 0.1 0.0 6.6 0.1 5.8 436.4 38.1 9.4 2.4 6.7 1.9 2.4 18.7 3.8 PBX3 ENSG00000167081 "PBX homeobox 3" P40426 9 125747345-125967377 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 153.1" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8;Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 192.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 39.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 13.9" "Lineage enriched" "Detected in all" 4 "dendritic cells: 13.9" "Cell line enhanced" "Detected in many" "THP-1: 90.1" "Region enhanced" "Detected in all" "olfactory bulb: 167.4" "Group enriched" "Detected in all" 5 "basal ganglia: 46.3;olfactory bulb: 161.9" HPA003881 Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA003881: AB_1855020" "unprognostic (1.97e-2)" "unprognostic (3.78e-2)" "unprognostic (1.15e-1)" "unprognostic (1.93e-2)" "unprognostic (1.27e-1)" "unprognostic (2.35e-1)" "unprognostic (2.20e-1)" "unprognostic (3.38e-2)" "unprognostic (2.83e-1)" "unprognostic (2.88e-1)" "unprognostic (2.42e-3)" "unprognostic (7.02e-2)" "unprognostic (1.53e-1)" "unprognostic (2.74e-2)" "unprognostic (1.63e-1)" "unprognostic (8.03e-2)" "unprognostic (6.29e-2)" 10.9 56.0 10.4 12.9 14.6 6.9 10.0 17.4 13.2 27.2 7.0 47.9 6.8 9.8 20.0 11.8 14.2 22.5 38.0 7.2 15.0 7.1 18.1 13.0 8.0 19.7 21.0 58.2 18.8 153.1 12.6 6.7 19.4 30.9 13.7 28.0 11.8 28.0 8.5 19.4 14.3 22.6 18.8 12.8 21.5 8.2 15.3 16.7 35.1 5.7 6.9 20.7 21.9 21.7 11.6 11.0 50.0 43.1 13.1 19.1 8.5 29.9 16.8 19.2 14.5 14.3 21.1 11.3 3.6 22.1 20.8 8.5 28.3 12.3 38.3 12.4 20.5 9.7 7.9 5.8 17.2 9.6 15.5 9.5 13.7 14.5 10.0 45.3 23.1 7.2 0.4 10.3 43.5 5.9 10.0 4.9 35.8 14.2 7.4 18.9 73.3 1.5 15.6 6.4 25.9 45.1 20.2 3.8 9.4 18.8 15.7 90.1 26.6 40.0 10.2 23.8 57.1 7.2 12.8 11.5 19.7 15.2 20.6 2.3 1.7 2.2 0.8 1.4 0.9 1.0 0.9 0.7 1.9 1.5 1.7 0.7 1.4 3.2 1.3 13.9 0.8 1.0 10.4 14.6 17.4 13.2 7.2 15.0 19.7 21.0 19.4 18.8 15.3 21.7 7.3 9.6 16.7 17.9 10.0 22.7 10.3 3.0 6.8 7.5 11.5 8.3 60.3 2.8 8.6 12.9 37.5 0.6 20.7 1.3 7.9 13.5 15.2 1.1 14.0 11.9 11.5 6.3 44.3 2.5 0.9 23.4 5.6 1.5 16.5 9.4 9.7 12.6 15.3 42.1 19.3 5.7 6.1 29.0 23.7 11.4 19.9 22.9 7.2 91.8 13.6 11.5 6.2 136.2 192.2 3.1 12.1 11.3 3.8 13.0 0.9 2.8 8.5 43.1 0.0 5.3 13.0 33.7 16.0 10.4 26.3 0.4 10.5 8.7 3.4 8.7 PCCB ENSG00000114054 "Propionyl-CoA carboxylase subunit beta" P05166 3 136250340-136337896 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 202.1" "Cell type enhanced" "Detected in all" "Early spermatids: 316.7;Late spermatids: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036939, HPA036940" Enhanced "Intracellular and membrane" NA NA 120000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "HPA036939: AB_10671366, HPA036940: AB_10669779" "unprognostic (2.74e-1)" "unprognostic (7.88e-3)" "unprognostic (3.99e-2)" "unprognostic (2.89e-2)" "unprognostic (2.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.05e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-2)" "unprognostic (2.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.47e-7)" "unprognostic (2.43e-2)" "unprognostic (2.64e-1)" "unprognostic (3.50e-1)" "unprognostic (4.13e-1)" 34.4 75.1 23.3 15.2 33.6 37.9 27.5 31.4 29.3 17.5 35.5 43.6 38.1 13.8 13.9 26.3 19.2 17.0 94.6 23.6 28.5 88.9 202.1 14.8 16.2 31.1 29.4 12.1 32.0 57.0 15.6 19.6 30.4 23.7 41.9 17.2 23.6 21.7 83.8 15.1 27.5 22.6 27.1 12.7 26.1 38.8 29.8 21.1 37.9 91.4 20.7 20.5 11.4 47.8 64.8 45.8 42.4 64.4 30.2 34.5 75.4 33.0 35.5 49.1 69.6 67.9 44.7 80.3 89.4 46.6 44.0 35.1 50.3 44.0 69.4 47.8 43.0 140.8 49.5 101.4 66.4 107.3 60.2 40.8 41.4 31.0 69.4 30.5 56.1 131.6 104.5 41.0 38.0 123.1 109.3 63.1 36.0 96.8 40.9 29.3 34.6 116.6 89.9 69.4 84.0 62.9 84.4 48.9 77.5 35.2 98.3 62.9 42.0 24.5 26.0 69.2 29.6 78.3 70.0 66.9 34.9 41.7 29.9 7.3 29.5 7.5 22.6 30.8 25.4 21.7 14.7 23.2 44.6 19.8 15.1 18.7 2.7 25.9 28.7 38.5 14.8 22.6 23.3 33.6 31.4 29.3 23.6 28.5 31.1 29.4 30.4 27.1 29.8 47.8 5.6 9.6 14.0 16.0 9.2 4.1 9.4 37.9 3.4 16.0 12.5 5.3 51.1 8.6 28.4 20.2 10.4 57.1 8.0 15.1 39.2 24.6 316.7 14.1 9.5 8.1 9.1 53.2 16.5 14.0 27.1 13.6 14.8 14.1 29.2 18.1 9.3 76.3 35.1 11.8 22.7 15.1 24.4 11.7 5.2 159.0 13.7 11.4 19.6 16.9 16.5 11.8 10.3 22.1 50.9 14.4 16.7 10.9 22.6 10.4 19.2 97.3 23.6 13.2 13.1 13.6 13.1 11.3 29.0 16.2 3.3 50.9 9.9 52.8 25.1 12.2 PCDH11X "PCDH-X, PCDH11, PCDHX, PPP1R119" ENSG00000102290 "Protocadherin 11 X-linked" Q9BZA7 X 91779261-92623230 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 10.7;ovary: 7.4" "Group enriched" "Detected in many" 6 "Excitatory neurons: 120.4;Inhibitory neurons: 349.7;Oligodendrocyte precursor cells: 173.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.5;AN3-CA: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077495 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA077495: " "unprognostic (4.22e-3)" "unprognostic (1.16e-1)" "unprognostic (1.39e-4)" "unprognostic (1.18e-1)" "unprognostic (8.20e-3)" "unprognostic (6.32e-2)" "unprognostic (9.10e-2)" "unprognostic (6.19e-2)" "unprognostic (4.58e-1)" "unprognostic (1.58e-1)" "unprognostic (2.45e-2)" "unprognostic (3.86e-1)" 0.0 0.2 10.7 0.2 7.7 0.0 0.2 0.0 3.7 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.4 6.2 0.0 0.0 0.0 0.2 1.6 4.8 7.4 0.0 1.0 0.2 0.8 2.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 7.8 0.0 0.1 0.2 0.2 0.0 0.0 1.2 0.0 0.0 1.5 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 7.7 0.0 3.7 2.4 6.2 1.6 4.8 2.0 0.0 7.8 1.2 0.5 9.6 7.4 2.3 0.2 1.5 0.5 0.2 1.2 4.2 1.0 1.8 0.7 0.0 3.2 0.0 0.0 20.8 0.1 0.1 0.0 0.0 0.6 0.2 0.1 2.1 0.0 0.0 120.4 0.0 0.3 1.0 0.0 0.2 1.3 0.1 4.6 0.3 1.0 33.7 349.7 0.0 0.0 0.0 2.0 0.6 9.6 1.0 10.6 12.2 0.0 0.2 0.0 173.9 5.3 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.8 1.4 6.6 0.6 0.8 0.3 1.0 0.1 0.9 15.7 0.6 0.1 0.1 0.4 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;lymphoid tissue: 25.1" "Group enriched" "Detected in many" 4 "Adipocytes: 57.6;Astrocytes: 77.1;Early spermatids: 60.7;Endothelial cells: 126.7;Excitatory neurons: 125.2;Hepatic stellate cells: 79.6;Inhibitory neurons: 67.9;Oligodendrocyte precursor cells: 193.0;Oligodendrocytes: 101.1;Spermatocytes: 68.3" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;HEK 293: 9.3;U-87 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" 1.6 1.8 15.8 1.8 20.6 0.0 0.8 7.9 13.9 2.2 0.1 1.2 0.8 2.1 0.8 0.6 2.0 3.2 2.2 11.7 25.5 1.9 1.0 14.0 0.6 9.3 15.8 0.5 6.0 1.6 0.9 4.4 11.4 1.0 0.8 1.0 0.7 0.7 1.7 0.3 0.8 2.1 7.6 25.1 1.5 8.8 27.9 0.2 2.9 1.3 0.5 2.7 0.8 10.5 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 9.3 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 1.2 0.0 1.0 0.0 0.0 0.0 5.3 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 20.6 7.9 13.9 11.7 25.5 9.3 15.8 11.4 7.6 27.9 10.5 57.6 0.0 4.3 77.1 0.1 2.7 0.1 0.0 1.2 7.1 0.4 0.6 6.0 1.5 8.6 1.8 0.0 0.2 0.5 0.1 0.0 11.1 60.7 2.6 2.0 126.7 0.0 0.0 125.2 8.3 0.1 11.7 0.0 19.8 0.0 20.5 79.6 0.3 0.6 0.0 67.9 0.0 0.0 1.9 2.5 19.0 1.8 0.5 10.6 12.2 1.6 2.3 0.0 193.0 101.1 1.3 0.0 1.2 1.2 0.3 0.0 0.0 5.1 0.0 6.6 1.9 10.7 68.3 10.6 0.4 1.0 0.0 1.1 1.6 0.0 0.4 PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568121 "Citric acid cycle related proteins, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Kinase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 432.1;liver: 681.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 703.8;Distal tubular cells: 588.9;Hepatocytes: 1184.0;Proximal enterocytes: 2209.9;Proximal tubular cells: 3547.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "ASC diff: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006277, HPA006507, CAB017027" Approved NA NA 840000 "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" 59.2 1.1 0.8 1.7 0.8 0.0 29.8 0.7 1.6 0.0 0.6 57.8 110.4 1.2 0.2 0.4 0.9 5.0 1.0 0.7 1.4 432.1 681.4 0.2 0.3 0.7 0.9 1.6 0.4 0.0 21.1 0.3 0.8 0.2 79.8 0.5 1.1 0.2 0.4 0.9 143.9 2.9 0.6 0.3 0.9 0.0 1.3 0.1 0.8 6.5 0.0 0.8 0.1 0.8 0.0 0.0 0.0 0.0 20.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.6 0.7 1.4 0.7 0.9 0.8 0.6 1.3 0.8 0.7 0.0 0.0 0.0 21.3 0.1 0.0 0.0 15.9 0.3 0.7 0.6 1.0 61.5 0.6 90.1 0.0 0.1 0.1 703.8 588.9 0.6 0.1 1.3 1.5 2.7 53.9 40.2 0.0 0.0 0.0 2.3 19.9 8.5 8.9 0.1 29.6 1184.0 0.0 3.3 0.0 293.6 0.0 22.6 0.0 0.0 0.0 12.8 0.0 1.9 0.0 9.9 0.0 0.0 0.0 0.1 285.5 0.0 0.0 0.0 2209.9 3547.9 0.0 0.4 0.0 0.3 6.0 0.0 0.1 10.3 0.3 0.3 10.2 1.5 348.5 0.1 PCLAF "KIAA0101, NS5ATP9, OEATC-1, p15(PAF), PAF15" ENSG00000166803 "PCNA clamp associated factor" Q15004 15 64364304-64387687 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 128.6;lymphoid tissue: 73.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 82.2;Extravillous trophoblasts: 160.2;Granulosa cells: 48.8;Hofbauer cells: 110.2;Syncytiotrophoblasts: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 4 "T-reg: 23.6" "Lineage enriched" "Detected in many" 4 "T-cells: 23.6" "Low cell line specificity" "Detected in all" HPA047929 Supported Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA047929: AB_2680215" "unprognostic (5.34e-2)" "unprognostic (1.36e-3)" "unprognostic (9.39e-2)" "unprognostic (1.28e-1)" "unprognostic (4.16e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.26e-5)" "unprognostic (4.38e-3)" "unprognostic (1.91e-3)" "unprognostic (7.26e-2)" "unprognostic (2.56e-3)" "unprognostic (9.65e-2)" "prognostic unfavorable (9.77e-15)" "unprognostic (5.59e-2)" "unprognostic (2.05e-1)" "unprognostic (8.65e-2)" "unprognostic (3.22e-1)" 2.1 1.4 0.9 22.9 1.0 128.6 3.9 1.4 1.1 1.7 0.8 19.0 14.7 4.5 1.2 15.2 1.3 2.5 0.4 0.9 0.6 1.2 3.6 2.5 49.5 1.0 0.8 0.4 1.9 0.8 0.5 8.7 0.9 2.0 22.6 0.3 2.3 0.3 0.4 6.7 15.8 5.0 0.5 7.4 8.1 1.1 1.0 73.8 2.2 0.1 47.1 7.9 4.9 1.9 212.6 165.8 154.4 140.8 15.9 60.9 134.4 146.2 84.8 185.4 276.4 198.4 202.1 343.7 46.4 57.4 64.8 153.6 340.7 83.1 235.3 192.5 124.8 352.5 202.5 209.8 1.5 285.3 153.8 20.0 7.9 156.4 31.9 52.3 168.9 175.9 201.3 104.4 248.1 187.8 268.0 605.5 73.9 179.9 73.4 416.6 353.8 247.1 115.9 200.2 19.1 86.7 112.8 105.2 69.3 78.9 153.8 365.3 36.3 158.4 308.6 177.8 386.7 65.5 223.4 229.0 67.7 512.9 108.5 2.4 0.3 0.9 1.4 0.2 0.2 2.0 4.4 4.2 2.8 0.6 0.5 1.0 2.7 5.7 0.4 0.3 23.6 2.3 0.9 1.0 1.4 1.1 0.9 0.6 1.0 0.8 0.9 0.5 1.0 1.9 0.5 9.6 11.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 27.5 25.5 0.0 0.0 5.0 1.8 0.0 82.2 8.3 0.0 1.9 6.5 0.0 18.6 10.4 8.5 0.0 0.0 0.0 3.0 160.2 25.4 0.0 13.8 3.8 48.8 0.0 0.0 110.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 4.3 0.0 0.0 3.0 3.6 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.0 42.1 5.8 7.6 0.0 0.0 PCNA ENSG00000132646 "Proliferating cell nuclear antigen" P12004 20 5114953-5126626 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" DNA-binding "Cancer-related genes, Deafness, Disease variant, Dwarfism, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 383.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000148, HPA030521, HPA030522, HPA030523" Enhanced Enhanced Nucleoplasm No Yes 170000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000148: AB_628110, HPA030521: AB_10600218, HPA030522: AB_10602096, HPA030523: AB_10602199" "unprognostic (5.21e-2)" "prognostic favorable (1.86e-5)" "unprognostic (2.96e-2)" "unprognostic (2.43e-1)" "unprognostic (3.17e-1)" "unprognostic (5.60e-3)" "prognostic unfavorable (2.61e-4)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.89e-2)" "unprognostic (1.01e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (3.03e-6)" "unprognostic (2.12e-2)" "unprognostic (2.29e-1)" "unprognostic (7.11e-3)" "unprognostic (7.46e-2)" 31.2 47.2 23.2 85.2 26.0 383.2 51.0 26.8 29.7 41.5 26.8 89.0 70.7 38.1 30.9 81.2 39.1 34.8 30.6 23.0 24.4 43.7 55.3 37.5 168.8 25.1 24.0 37.7 32.8 42.4 25.1 69.8 26.0 32.2 93.7 94.1 40.3 38.3 27.9 62.8 72.9 47.9 26.8 54.0 53.9 62.3 23.3 219.9 42.0 26.8 137.3 51.0 42.3 30.0 769.1 591.4 585.0 253.7 136.1 126.6 409.5 491.6 288.3 453.7 640.0 465.3 594.2 773.4 155.7 177.5 395.2 558.8 350.7 594.4 413.2 231.7 386.8 543.7 207.8 1098.3 57.8 753.7 233.0 92.6 138.2 387.2 91.7 95.3 263.3 503.6 493.9 631.2 449.7 278.3 1450.6 829.3 439.9 592.0 322.9 787.9 514.1 622.5 208.5 441.1 500.8 339.4 345.1 524.6 351.9 213.9 371.2 378.0 177.2 324.3 373.3 461.5 572.0 317.2 981.6 1313.9 145.9 707.4 426.2 5.0 23.2 18.5 36.5 23.3 45.7 33.5 45.7 37.1 32.6 29.2 41.6 37.3 7.7 43.6 24.7 29.9 48.1 36.7 23.2 26.0 26.8 29.7 23.0 24.4 25.1 24.0 26.0 26.8 23.3 30.0 32.4 44.8 26.0 2.9 40.6 67.7 44.4 121.4 44.3 42.1 27.5 45.2 14.5 21.5 60.5 58.8 27.1 171.5 44.3 42.9 60.7 51.6 176.0 30.2 21.4 34.8 19.9 189.0 4.3 39.6 175.6 38.7 21.9 27.7 22.7 53.1 29.6 27.1 96.7 32.0 5.9 53.9 75.3 24.2 33.4 109.1 36.1 32.7 37.4 3.7 47.6 74.0 23.7 4.0 13.5 28.3 20.3 40.3 56.6 23.3 33.3 46.1 44.1 97.1 52.6 29.2 46.1 149.1 101.1 65.5 49.7 66.4 48.6 29.6 84.5 40.4 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;heart muscle: 123.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 138.0;Extravillous trophoblasts: 63.1;Fibroblasts: 225.8;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 65.5;RPMI-8226: 36.8;U-2197: 77.9;U-266/70: 68.6;U-266/84: 34.3" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 580000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" 87.6 2.8 0.8 4.0 0.9 14.9 29.1 0.4 1.0 21.5 0.8 6.9 0.1 4.2 2.2 7.8 3.9 1.5 123.2 1.3 1.9 17.9 18.3 16.4 2.3 0.7 1.1 3.9 1.4 0.7 23.7 48.1 0.6 21.5 5.1 0.7 3.1 8.9 2.4 5.3 2.8 8.7 0.5 3.0 3.4 2.4 1.5 0.7 6.4 22.1 1.9 25.7 26.0 0.8 1.4 11.0 3.4 0.0 65.5 18.1 0.0 1.0 0.2 2.9 3.6 0.7 1.2 0.0 3.3 4.9 14.8 0.1 13.7 0.0 3.4 0.0 21.0 2.5 6.8 0.0 0.0 1.5 0.0 6.9 0.0 6.9 1.7 14.5 0.2 2.2 0.5 0.0 1.4 2.0 4.5 1.2 5.5 0.2 21.9 0.0 8.1 36.8 3.2 0.1 7.6 4.6 17.8 0.0 6.5 4.7 0.0 4.5 0.0 5.8 12.8 77.9 6.0 68.6 34.3 0.0 16.6 1.9 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.4 1.0 1.3 1.9 0.7 1.1 0.6 0.5 1.5 0.8 17.3 0.0 3.2 0.7 0.2 7.4 0.7 0.9 0.6 18.0 0.5 0.6 37.3 0.0 0.9 12.9 25.0 138.0 0.2 0.2 0.0 0.0 0.6 2.1 2.2 4.5 0.0 0.0 1.6 0.0 63.1 225.8 0.5 3.7 1.3 29.0 0.4 11.8 15.3 6.7 2.2 0.2 0.0 0.6 12.4 1.0 0.6 6.7 3.6 1.9 0.0 13.8 0.0 29.7 1.6 0.5 0.4 0.0 0.0 2.1 0.0 0.0 0.0 12.6 0.0 6.1 16.9 25.8 47.7 1.0 7.4 241.6 1.1 19.1 0.0 0.4 PCP4 PEP-19 ENSG00000183036 "Purkinje cell protein 4" P48539 21 39867438-39929397 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 647.3;seminal vesicle: 1280.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 600.9;Distal tubular cells: 645.6;Horizontal cells: 1398.2;Proximal tubular cells: 941.2" "Cancer enhanced" "Detected in many" "prostate cancer: 41.7;thyroid cancer: 48.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 215.9;T-47d: 64.7" "Low region specificity" "Detected in all" HPA005792 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nucleoli fibrillar center" "HPA005792: AB_1855086" "unprognostic (6.82e-2)" "prognostic favorable (9.76e-4)" "unprognostic (5.26e-2)" "unprognostic (1.56e-1)" "unprognostic (4.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.87e-2)" "unprognostic (1.07e-1)" "unprognostic (1.04e-1)" "unprognostic (3.95e-3)" "unprognostic (2.63e-1)" "prognostic favorable (1.85e-7)" "unprognostic (9.00e-2)" "unprognostic (2.99e-3)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" 5.2 52.9 197.6 2.0 647.3 0.0 8.4 166.2 202.0 180.9 509.6 135.5 5.1 126.9 365.6 228.2 10.2 4.2 4.6 121.8 175.9 52.1 0.5 0.6 0.2 75.6 299.1 3.5 6.2 19.7 8.8 2.0 70.2 323.4 32.4 385.3 21.3 1280.1 0.6 14.8 6.0 54.6 64.1 2.6 7.1 0.9 491.1 7.9 227.7 0.0 1.0 468.0 128.6 85.5 0.0 0.0 3.1 0.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 2.3 1.9 0.0 0.0 0.0 0.0 215.9 0.5 0.0 0.3 0.3 0.0 34.8 0.0 0.2 64.7 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 197.6 647.3 166.2 202.0 121.8 175.9 75.6 299.1 70.2 64.1 491.1 85.5 0.0 0.0 1.5 15.3 2.9 3.1 0.4 0.0 0.0 600.9 0.4 0.4 8.8 2.8 0.0 77.3 62.6 0.3 0.0 0.1 645.6 0.4 1.3 0.0 0.2 5.0 1.2 0.0 71.3 0.2 0.3 1.5 0.0 0.0 0.0 0.4 0.0 0.1 0.2 1398.2 21.5 0.2 0.0 0.0 7.5 0.4 9.6 7.0 21.4 8.4 0.0 68.4 0.0 7.5 11.9 0.8 0.2 0.4 0.0 4.4 0.0 941.2 0.0 200.0 0.0 0.0 77.4 3.4 9.5 0.0 6.0 2.9 2.2 0.5 0.5 1.0 PCP4L1 IQM1 ENSG00000248485 "Purkinje cell protein 4 like 1" A6NKN8 1 161258745-161285450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.7;pituitary gland: 84.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 35.8;Bipolar cells: 82.8;Inhibitory neurons: 34.0;Sertoli cells: 19.7;Squamous epithelial cells: 23.5;Urothelial cells: 39.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "RT4: 13.8;T-47d: 8.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 206.6" HPA052833 Enhanced Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA052833: AB_2681968" "unprognostic (1.81e-2)" "unprognostic (9.39e-2)" "unprognostic (5.25e-2)" "unprognostic (2.07e-1)" "unprognostic (3.03e-2)" "unprognostic (1.87e-2)" "unprognostic (2.51e-1)" "prognostic favorable (8.10e-5)" "unprognostic (2.39e-1)" "unprognostic (1.92e-1)" "unprognostic (4.93e-2)" "unprognostic (7.37e-2)" "unprognostic (3.63e-5)" "unprognostic (4.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (6.15e-2)" 2.7 0.4 14.1 0.8 71.7 0.1 1.8 19.6 33.2 4.0 0.9 5.6 1.7 1.8 2.6 18.8 2.1 2.0 0.8 6.8 14.7 0.9 4.0 4.6 0.2 39.7 23.3 2.2 0.5 0.4 84.3 0.3 39.8 11.0 2.5 39.2 1.9 16.4 0.4 5.6 2.8 6.6 28.1 0.3 2.0 1.8 15.2 2.0 0.7 1.5 2.6 35.6 17.1 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 13.8 1.9 0.0 0.0 0.2 0.0 0.2 8.9 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 14.1 71.7 19.6 33.2 6.8 14.7 39.7 23.3 39.8 28.1 15.2 13.9 0.0 3.2 6.4 2.0 0.0 0.0 35.8 8.3 12.5 82.8 3.2 1.0 0.2 0.0 7.6 0.0 6.2 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.3 0.0 0.0 3.1 1.3 1.9 0.2 4.6 0.3 1.3 0.0 0.0 0.9 0.1 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.8 0.0 3.5 0.0 5.0 1.4 0.2 0.0 1.9 0.0 2.5 0.0 0.6 0.9 5.9 19.7 0.0 10.0 1.3 1.5 23.5 0.3 1.8 0.0 0.0 0.0 39.9 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 28.5;brain: 30.2;retina: 35.8;thyroid gland: 56.9" "Cell type enhanced" "Detected in many" "Early spermatids: 87.3;Excitatory neurons: 322.8;Horizontal cells: 132.9;Inhibitory neurons: 148.8;Melanocytes: 209.9;Muller glia cells: 452.7" "Cancer enriched" "Detected in many" 4 "thyroid cancer: 65.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 60.0;SCLC-21H: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" NA NA 18000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA049627: AB_2680835" "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 0.7 28.5 8.6 0.8 14.9 0.5 0.4 0.1 30.2 1.6 0.0 6.9 4.8 0.2 0.3 1.1 1.0 0.5 4.7 15.8 11.1 0.2 0.2 2.5 0.0 2.2 1.3 9.0 19.8 0.8 2.0 0.6 2.6 1.4 1.7 35.8 1.7 1.2 0.1 14.1 2.1 0.4 1.4 0.1 8.1 4.8 13.2 0.0 56.9 0.1 0.1 3.0 2.4 11.9 0.0 0.0 60.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 14.9 0.1 30.2 15.8 11.1 2.2 1.3 2.6 1.4 13.2 11.9 0.1 0.0 7.3 7.8 0.0 8.2 0.0 0.0 1.2 28.1 0.0 0.0 1.2 0.0 0.6 0.0 6.2 0.0 0.0 0.0 0.0 0.0 87.3 0.0 0.0 1.3 0.0 0.0 322.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 132.9 148.8 0.6 0.0 0.0 1.3 6.3 2.8 0.2 209.9 8.4 0.0 452.7 0.0 44.7 6.4 2.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.5 1.2 1.0 0.3 0.2 1.4 0.0 0.1 0.6 0.0 0.1 PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 153.6;liver: 160.0;lymphoid tissue: 81.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 231.6;Horizontal cells: 196.9;Oligodendrocytes: 561.9;Theca cells: 106.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 47.2;CACO-2: 35.7;HEK 293: 60.3;Hep G2: 53.8;OE19: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" NA NA 480000 "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA004774: AB_1079583" "prognostic favorable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" 5.3 2.2 17.5 3.0 67.3 1.1 11.2 57.8 37.0 2.2 4.2 16.5 6.8 2.0 3.3 9.0 2.8 3.1 20.0 19.3 34.1 3.2 160.0 3.6 2.5 113.0 64.5 6.1 2.6 0.6 5.1 32.0 95.6 3.1 14.8 7.6 2.8 0.6 11.4 10.1 10.1 3.6 42.9 81.4 9.8 13.0 54.0 20.9 2.2 16.3 1.8 3.7 2.6 153.6 19.7 14.6 2.6 0.9 0.2 0.4 47.2 0.7 2.5 0.0 0.1 35.7 8.3 0.4 2.4 0.6 1.1 11.4 12.5 1.5 0.0 2.8 60.3 33.5 8.4 53.8 1.6 4.5 0.4 0.3 7.5 0.2 0.2 0.2 0.1 4.3 24.5 0.2 0.0 8.8 0.1 4.7 9.3 65.9 6.5 0.2 0.4 4.4 4.4 25.4 7.3 8.6 26.2 1.5 9.1 6.6 2.2 21.9 0.2 0.3 1.2 0.3 0.2 0.5 0.6 0.7 0.2 0.6 7.3 0.8 0.2 0.9 0.2 0.4 0.3 0.5 0.4 0.2 0.1 1.0 0.6 0.5 0.4 3.3 1.3 0.4 0.1 1.2 17.5 67.3 57.8 37.0 19.3 34.1 113.0 64.5 95.6 42.9 54.0 153.6 1.7 3.2 0.6 2.9 1.3 0.4 0.3 0.9 0.6 1.7 15.4 6.6 2.0 8.6 1.4 1.8 20.9 6.7 0.6 22.6 0.0 0.6 1.6 4.7 21.6 4.9 0.0 3.2 19.4 0.8 24.3 15.5 1.5 6.9 0.0 4.2 12.5 231.6 1.4 196.9 30.8 3.7 0.0 5.2 1.1 2.4 10.5 1.7 0.0 5.6 1.0 1.7 3.1 25.6 561.9 7.3 8.2 0.0 0.0 1.7 2.3 0.1 1.2 1.6 0.0 2.0 1.0 4.7 2.4 0.9 0.1 3.3 1.0 106.5 8.5 0.2 PCYT1A "CT, CTPCT, PCYT1" ENSG00000161217 "Phosphate cytidylyltransferase 1, choline, alpha" P49585 3 196214222-196287957 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Cone-rod dystrophy, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035428 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA035428: AB_10602045" "unprognostic (8.58e-3)" "unprognostic (2.63e-1)" "unprognostic (8.45e-2)" "unprognostic (8.61e-3)" "unprognostic (2.87e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (8.52e-2)" "unprognostic (5.99e-2)" "unprognostic (1.65e-2)" "unprognostic (6.72e-3)" "unprognostic (1.74e-2)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.47e-2)" "unprognostic (7.16e-3)" "unprognostic (2.41e-2)" 31.4 24.4 15.2 30.0 16.0 45.3 21.0 16.6 15.8 16.7 17.8 25.7 60.3 19.1 13.9 31.0 15.6 20.7 46.4 15.5 21.1 18.3 20.7 22.5 22.9 18.8 18.0 15.8 16.8 22.7 12.9 20.1 18.5 16.6 22.9 14.4 19.3 18.6 73.8 43.0 49.1 23.0 17.5 25.9 24.2 22.4 18.1 18.1 17.2 42.1 26.8 21.0 19.8 17.1 92.6 36.6 25.8 37.2 52.2 53.9 37.0 68.2 47.1 59.2 51.8 92.3 32.8 23.9 215.2 78.1 60.2 71.4 40.5 52.1 50.4 42.1 28.6 68.6 40.6 39.5 45.2 34.3 56.7 47.4 40.0 55.9 39.6 35.4 63.0 21.0 38.3 53.3 58.1 79.6 19.9 17.3 21.4 55.7 53.0 34.5 31.0 37.5 35.7 53.6 25.4 18.3 44.5 79.5 44.2 32.8 114.1 37.2 88.5 45.5 25.2 61.8 92.7 45.8 101.1 44.1 69.6 43.8 56.9 9.6 9.2 10.4 8.8 9.3 7.5 7.2 6.5 9.7 9.1 6.3 4.2 6.3 21.0 9.4 11.0 5.9 14.9 5.2 15.2 16.0 16.6 15.8 15.5 21.1 18.8 18.0 18.5 17.5 18.1 17.1 24.7 16.0 25.7 15.3 19.9 14.5 9.4 19.7 14.2 15.9 14.1 9.4 70.1 20.0 17.5 14.7 25.0 11.9 27.3 36.4 13.7 24.8 76.3 17.8 22.9 23.2 22.1 12.2 20.4 22.9 17.7 17.0 23.4 15.6 20.8 16.1 26.7 35.6 37.4 8.4 22.7 24.2 6.1 34.6 27.1 67.6 19.9 33.9 19.6 20.6 39.4 13.1 39.1 16.1 17.6 24.6 21.1 28.2 27.2 12.0 67.2 23.2 33.9 12.8 26.3 15.0 19.0 46.0 13.2 30.0 21.5 18.6 25.6 25.5 23.8 12.2 PDCD1 "CD279, hSLE1, PD-1, PD1, SLEB2" ENSG00000188389 "Programmed cell death 1" Q15116 2 241849884-241858894 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Immunity" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.7;lymphoid tissue: 16.1" "Group enriched" "Detected in some" 4 "Plasma cells: 9.5;T-cells: 34.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.4" "Group enriched" "Detected in many" 5 "gdT-cell: 4.4;MAIT T-cell: 4.8;memory CD4 T-cell: 8.7;memory CD8 T-cell: 12.4;T-reg: 4.3" "Lineage enriched" "Detected in single" 55 "T-cells: 12.4" "Cell line enhanced" "Detected in some" "JURKAT: 1.5;MOLT-4: 2.4;RPMI-8226: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035981, CAB038418, CAB076386" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB038418: AB_1160824, CAB076386: AB_881954, HPA035981: AB_10669664" "unprognostic (2.90e-3)" "unprognostic (4.50e-3)" "unprognostic (7.78e-2)" "prognostic favorable (9.44e-5)" "unprognostic (7.18e-3)" "unprognostic (1.31e-3)" "unprognostic (3.83e-2)" "unprognostic (7.33e-2)" "unprognostic (5.82e-3)" "unprognostic (3.75e-2)" "unprognostic (6.57e-2)" "unprognostic (3.94e-1)" "prognostic unfavorable (3.48e-7)" "unprognostic (1.20e-2)" "unprognostic (3.10e-1)" "unprognostic (5.35e-2)" "unprognostic (5.06e-3)" 1.2 0.3 0.0 3.2 0.2 0.9 0.4 0.0 0.1 0.6 0.2 0.8 0.3 0.4 0.0 0.8 0.6 0.3 6.7 0.1 0.1 0.7 0.4 1.8 16.1 0.1 1.4 0.2 0.3 0.0 1.5 0.0 0.2 0.7 0.1 0.0 1.0 0.2 0.1 0.3 3.8 0.2 0.1 7.0 1.8 0.3 0.4 3.1 1.5 0.0 4.0 1.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.3 2.4 0.0 0.0 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 4.8 0.2 8.7 12.4 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 4.3 2.1 0.0 0.2 0.0 0.1 0.1 0.1 0.1 1.4 0.2 0.1 0.4 0.2 0.4 0.0 0.6 0.0 3.6 0.4 0.3 0.0 0.0 0.0 0.3 0.5 0.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.6 0.0 34.7 0.0 0.0 0.1 PDCL3 VIAF1 ENSG00000115539 "Phosducin like 3" Q9H2J4 2 100562993-100576739 "Predicted intracellular proteins" "Angiogenesis, Apoptosis" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018469, HPA027094" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA018469: AB_1855116, HPA027094: AB_10601387" "unprognostic (1.34e-1)" "unprognostic (8.30e-2)" "unprognostic (2.20e-1)" "unprognostic (3.32e-2)" "unprognostic (5.07e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.07e-5)" "unprognostic (1.44e-1)" "unprognostic (5.46e-2)" "unprognostic (1.66e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (8.22e-2)" "prognostic favorable (4.23e-4)" 20.8 22.0 19.1 27.1 21.6 22.9 23.0 21.6 24.3 18.9 16.6 27.3 17.0 24.1 37.2 36.8 22.5 21.3 30.6 18.4 21.3 28.4 18.5 18.4 25.3 21.8 24.7 21.1 11.4 23.4 10.5 23.4 21.7 27.0 28.9 21.1 16.9 23.2 58.8 36.8 17.3 38.6 20.8 17.0 17.6 22.8 22.1 22.4 21.4 34.3 34.0 33.1 17.5 22.2 41.8 58.7 59.9 52.2 19.3 27.4 67.5 51.3 32.5 92.9 58.1 74.2 25.5 68.6 74.0 62.3 122.3 34.2 76.0 50.2 74.0 110.6 65.8 72.0 31.8 89.7 50.8 77.3 73.2 29.8 92.0 82.0 52.3 24.2 58.9 52.8 61.1 43.8 70.7 74.6 75.8 117.7 77.9 45.6 86.6 72.5 63.2 48.0 58.2 98.7 55.9 49.6 41.0 54.7 59.0 48.6 42.3 53.0 45.8 56.4 60.1 44.8 72.2 26.4 54.1 68.3 34.4 90.5 45.7 82.3 64.8 80.2 63.1 124.4 72.8 92.5 95.0 70.4 114.9 78.1 97.7 75.4 7.0 93.9 161.7 64.0 113.6 87.3 19.1 21.6 21.6 24.3 18.4 21.3 21.8 24.7 21.7 20.8 22.1 22.2 37.4 19.2 25.2 1.6 39.5 65.6 36.6 79.2 52.9 13.0 24.8 36.2 40.9 18.6 46.1 14.7 6.2 70.8 61.5 16.0 60.7 50.6 37.0 38.9 26.6 30.2 19.8 21.7 2.3 39.1 51.2 22.6 19.4 34.6 92.9 25.4 12.5 17.0 59.7 11.8 2.0 24.0 89.5 17.8 80.7 14.3 14.6 54.4 35.6 3.7 104.3 19.7 40.2 2.0 4.5 31.8 18.6 33.4 27.7 33.2 19.7 77.9 28.1 16.5 52.6 23.8 54.1 5.5 66.9 63.2 57.5 52.4 91.8 24.5 31.3 32.4 PDE10A ENSG00000112541 "Phosphodiesterase 10A" Q9Y233 6 165327287-165988078 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 67.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 204.7;Inhibitory neurons: 209.6;Microglial cells: 89.0;Oligodendrocyte precursor cells: 48.7;Oligodendrocytes: 51.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 67.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 9.0;LHCN-M2: 12.5;RT4: 6.9;SH-SY5Y: 8.1;TIME: 11.3;U-2 OS: 7.0" "Region enriched" "Detected in all" 11 "basal ganglia: 350.1" "Region enriched" "Detected in all" 5 "basal ganglia: 194.1" "CAB045998, HPA047200" Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB045998: AB_2162589, HPA047200: AB_2679981" "unprognostic (1.02e-1)" "unprognostic (3.63e-2)" "unprognostic (3.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.20e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (6.03e-2)" "unprognostic (3.79e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (4.44e-7)" "unprognostic (3.59e-3)" "unprognostic (2.37e-2)" "unprognostic (3.44e-2)" "unprognostic (5.90e-3)" 2.6 1.3 3.1 0.8 67.2 0.0 2.3 5.5 10.7 1.3 0.0 1.0 0.2 2.0 2.4 0.4 2.4 1.5 3.6 2.1 2.5 3.8 0.3 1.0 0.5 1.6 2.3 2.3 0.5 0.5 2.7 2.5 0.9 1.7 0.2 1.9 0.4 1.7 0.4 0.3 0.7 2.1 0.5 1.4 1.1 3.4 9.6 0.3 6.0 0.5 0.4 3.2 0.9 0.1 0.0 2.4 5.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.3 0.8 0.0 0.0 0.0 3.8 0.1 2.2 0.0 0.0 0.1 3.9 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 5.5 0.0 0.0 0.0 12.5 0.3 0.9 0.0 1.1 0.0 4.7 1.5 5.8 0.0 5.9 6.9 1.8 8.1 0.0 0.0 0.4 0.7 0.0 0.0 11.3 0.1 7.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 67.2 5.5 10.7 2.1 2.5 1.6 2.3 0.9 0.5 9.6 0.1 13.8 0.0 0.0 10.4 0.1 0.4 3.3 0.4 0.0 7.2 0.3 0.3 7.3 0.0 1.2 5.5 2.1 7.8 0.0 0.0 3.9 2.0 14.3 0.2 1.7 13.4 0.0 0.0 204.7 0.0 6.1 6.6 1.1 0.4 1.3 0.1 7.9 0.0 0.8 16.8 209.6 0.0 0.0 0.0 0.0 14.9 0.0 0.2 1.8 89.0 0.0 12.6 0.0 48.7 51.8 0.1 0.0 0.4 0.0 17.9 0.0 7.2 0.9 1.1 0.0 12.4 5.0 8.8 2.1 0.1 0.3 2.9 0.1 1.6 0.1 6.9 PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623244-178072777 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 6.3;parathyroid gland: 9.8" "Cell type enhanced" "Detected in many" "Early spermatids: 37.0;Hepatocytes: 11.1;Late spermatids: 46.4;Oligodendrocytes: 14.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.6;fHDF/TERT166: 2.4;HAP1: 1.4;Hep G2: 2.8" HPA034560 Approved "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA034560: AB_10602140" "unprognostic (1.02e-1)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.61e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.91e-1)" "unprognostic (9.95e-2)" "unprognostic (2.80e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-4)" "unprognostic (1.64e-3)" 2.3 0.3 0.8 0.1 2.0 0.2 1.7 1.9 1.2 0.6 0.6 0.5 0.8 1.2 0.4 0.0 0.3 0.4 0.3 0.6 2.1 0.5 6.3 0.0 0.0 2.5 2.1 0.4 1.1 9.8 0.9 0.0 2.7 5.2 0.4 1.4 1.4 0.8 4.4 0.1 0.5 1.1 3.7 0.1 0.4 2.8 1.9 0.1 1.3 1.3 0.0 0.0 0.1 3.2 0.0 0.4 0.2 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.3 0.2 1.6 0.0 0.6 2.4 0.3 0.1 1.4 0.0 0.0 0.0 0.9 1.1 0.1 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.2 0.2 0.4 0.1 0.6 0.0 0.3 0.2 0.0 0.2 0.0 0.5 0.0 0.3 0.7 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.8 2.0 1.9 1.2 0.6 2.1 2.5 2.1 2.7 3.7 1.9 3.2 0.1 0.0 0.0 2.3 0.2 0.6 1.4 0.1 0.0 1.7 4.2 0.8 0.0 1.5 0.1 0.0 0.0 0.1 0.3 0.8 0.0 0.8 37.0 0.3 0.2 0.6 6.7 2.7 1.6 6.7 0.0 0.6 0.0 0.2 0.0 0.0 1.4 11.1 0.1 0.0 8.2 0.9 6.1 1.2 2.1 46.4 1.5 0.3 0.0 0.0 0.0 4.7 0.0 6.0 14.9 2.3 0.0 0.7 0.0 5.4 0.6 1.3 0.1 1.0 0.0 2.0 0.6 6.8 6.9 0.0 1.3 0.3 0.3 0.3 1.3 1.0 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Astrocytes: 98.2;Bipolar cells: 38.4;Cardiomyocytes: 131.3;Horizontal cells: 52.2;Inhibitory neurons: 78.8;Smooth muscle cells: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.6;HEL: 15.3;HeLa: 42.5;HUVEC TERT2: 7.4;SH-SY5Y: 17.9;U-138 MG: 11.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.8" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 6.5 1.0 1.6 3.1 1.3 0.2 3.8 3.1 1.3 6.7 1.8 15.0 1.9 4.2 1.4 2.2 4.1 4.7 43.4 1.3 1.5 3.3 1.3 3.9 1.0 1.9 2.3 3.4 6.2 0.6 2.1 11.3 1.2 5.4 7.6 5.7 2.7 3.5 2.2 1.3 9.6 5.2 1.6 2.2 5.1 0.4 2.5 0.6 2.8 1.8 0.5 2.5 3.1 1.4 0.0 0.2 8.6 0.0 1.9 1.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.3 42.5 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 1.1 0.0 0.0 0.0 2.7 0.0 0.1 17.9 0.0 0.0 0.1 3.3 0.0 0.0 0.3 11.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.3 1.3 1.5 1.9 2.3 1.2 1.6 2.5 1.4 2.7 0.0 0.0 98.2 0.0 0.3 0.2 0.0 0.6 38.4 0.2 0.3 131.3 4.3 0.6 0.0 0.0 0.0 0.0 28.4 0.0 5.8 0.7 0.5 1.6 3.9 4.2 0.0 4.1 0.5 0.0 11.3 0.0 1.4 17.1 0.0 2.2 0.0 0.7 52.2 78.8 7.0 0.0 0.0 0.7 0.6 1.5 3.1 1.8 27.2 0.5 4.4 0.0 27.6 3.9 0.4 26.9 0.7 0.0 0.5 33.4 3.1 0.0 2.8 6.6 3.6 49.9 0.3 0.9 0.9 0.3 0.0 0.6 0.5 16.4 0.2 PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469630 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 190.8;Late spermatids: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 36.5;NB-4: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB017632: AB_1127109, HPA043310: AB_2678419, HPA076091: AB_2686775" "unprognostic (1.29e-2)" "unprognostic (3.98e-2)" "unprognostic (8.91e-2)" "unprognostic (1.82e-1)" "unprognostic (7.00e-2)" "unprognostic (6.84e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-2)" "unprognostic (6.90e-2)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (1.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.15e-1)" 13.7 5.6 10.9 5.9 12.5 5.4 9.7 3.0 32.3 12.4 0.0 11.0 2.7 9.8 1.4 4.1 7.5 6.6 12.5 11.8 7.9 7.0 2.5 13.0 3.2 21.9 7.1 1.5 12.7 22.2 3.9 6.5 20.8 8.4 4.0 5.3 9.8 4.8 37.9 5.4 6.5 6.2 1.1 8.2 12.9 24.5 13.0 1.6 11.0 16.9 2.6 8.2 8.2 15.7 0.1 2.5 0.5 6.7 18.7 11.1 3.7 5.6 11.1 0.7 1.9 6.0 5.4 2.6 16.1 14.6 0.4 0.6 3.9 0.7 0.4 6.7 5.5 23.7 8.1 6.7 12.3 3.9 36.5 8.3 0.8 6.2 0.0 0.7 5.3 2.1 18.9 5.5 4.0 1.7 2.3 43.3 2.9 6.7 4.7 15.6 3.7 20.3 0.9 1.4 4.2 1.5 0.4 0.2 6.2 1.0 0.8 7.8 11.2 8.3 10.5 5.7 3.7 10.9 0.9 12.4 3.5 0.3 6.7 4.1 1.7 3.4 0.8 2.5 0.4 0.1 0.3 1.1 2.0 0.0 0.0 0.4 0.1 3.0 2.7 0.1 0.7 1.1 10.9 12.5 3.0 32.3 11.8 7.9 21.9 7.1 20.8 1.1 13.0 15.7 9.4 3.2 11.6 6.2 10.8 10.1 2.6 2.5 1.8 25.6 6.4 4.3 7.7 8.6 5.5 9.2 0.0 0.5 58.9 7.1 0.0 3.1 48.9 2.1 20.7 8.6 0.0 1.7 39.4 12.9 4.8 12.1 7.1 3.6 31.8 0.3 10.4 0.9 10.2 55.5 43.5 5.1 6.1 22.1 190.8 197.0 17.4 53.9 14.2 12.2 15.4 1.2 22.6 12.5 1.5 12.3 3.8 18.0 27.0 3.0 0.1 0.2 6.9 3.6 6.6 9.0 10.2 8.6 8.5 0.5 8.1 0.4 37.0 1.0 6.8 1.3 PDE6A "PDEA, RP43" ENSG00000132915 "Phosphodiesterase 6A" P16499 5 149857953-149944793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "retina: 1119.5" "Cell type enriched" "Detected in many" 11 "Rod photoreceptor cells: 2946.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 5 "CACO-2: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016970, HPA074677" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 39: CACO-2 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA016970: AB_1855125, HPA074677: AB_2732264" "unprognostic (6.85e-2)" "unprognostic (8.84e-2)" "unprognostic (1.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (4.39e-3)" "unprognostic (8.83e-2)" "unprognostic (6.54e-2)" "unprognostic (5.91e-3)" "unprognostic (1.77e-2)" "unprognostic (9.21e-2)" "unprognostic (7.57e-5)" "unprognostic (9.93e-2)" "unprognostic (3.08e-1)" "unprognostic (1.31e-1)" "unprognostic (2.26e-2)" 0.1 0.7 0.5 0.2 0.5 0.9 0.2 1.4 0.7 0.1 0.2 1.2 0.2 0.1 16.3 0.9 0.2 0.2 0.2 0.5 0.5 0.1 0.1 0.3 0.1 0.3 0.3 0.2 0.2 0.2 1.7 0.1 0.5 0.3 0.9 1119.5 0.4 0.2 0.3 0.6 0.1 0.1 0.2 0.2 0.2 1.5 0.6 0.0 0.4 0.0 0.2 0.0 0.1 1.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 2.5 0.2 0.3 0.4 0.0 0.4 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.2 0.2 0.0 0.0 0.1 0.4 0.4 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.0 0.2 0.0 0.1 0.3 0.1 0.4 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.1 1.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.6 0.2 0.1 0.2 0.1 0.0 0.5 0.5 1.4 0.7 0.5 0.5 0.3 0.3 0.5 0.2 0.6 1.2 0.9 0.0 5.8 0.0 0.4 1.1 0.6 0.8 0.0 150.5 0.5 0.4 6.7 0.0 2.8 0.0 244.0 1.1 1.6 14.3 0.0 0.1 18.4 1.5 0.5 11.6 0.0 0.0 1.2 0.2 2.2 1.2 0.0 2.5 3.8 1.9 2.2 0.6 0.3 75.7 0.6 0.4 2.0 1.9 0.4 5.5 1.2 1.5 0.0 0.0 1.4 263.1 5.2 0.5 0.2 0.1 2.8 0.4 0.3 0.4 0.4 0.1 3.2 2946.4 0.0 1.0 1.2 2.3 0.8 5.4 0.6 2.9 1.5 2.2 2.7 0.2 PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653621-42775509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 90.8;Paneth cells: 105.3;Proximal enterocytes: 233.5" "Cancer enriched" "Detected in all" 5 "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 29.7;EFO-21: 30.0;MCF7: 23.2;NB-4: 34.7;NTERA-2: 41.2;SCLC-21H: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011380, HPA011978" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoplasm, Plasma membrane" "HPA011380: AB_1855132, HPA011978: " "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" 9.4 11.1 12.3 3.9 15.1 0.5 10.8 14.0 12.9 7.2 8.6 74.7 2.9 5.1 19.4 3.7 10.6 6.8 4.3 10.6 12.6 29.8 4.2 4.9 4.8 12.4 14.4 3.5 4.1 6.5 9.9 10.3 12.7 38.5 16.4 10.7 12.7 15.8 2.4 7.0 47.3 8.8 11.0 18.3 13.4 1.9 15.0 7.8 6.5 4.8 3.1 18.9 6.2 12.0 0.0 2.8 29.7 3.7 0.0 0.8 0.5 0.0 0.0 0.0 0.0 3.2 18.2 0.0 30.0 0.0 2.2 0.0 2.7 9.8 0.0 0.0 10.4 0.0 0.0 6.4 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.0 0.0 23.2 1.5 34.7 41.2 14.6 0.0 0.0 0.0 1.2 20.4 7.6 22.5 13.5 5.2 0.0 0.5 7.0 0.2 19.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.1 0.2 3.1 0.6 0.4 0.9 0.0 0.4 1.0 0.3 12.3 15.1 14.0 12.9 10.6 12.6 12.4 14.4 12.7 11.0 15.0 12.0 18.6 3.2 5.0 43.4 1.6 1.0 10.9 4.2 6.2 26.4 13.4 12.6 1.6 5.7 2.4 18.4 0.0 0.0 1.0 90.8 29.4 7.3 0.6 18.1 8.5 11.9 13.1 3.2 5.6 2.4 0.1 5.9 1.5 26.8 1.3 6.1 5.7 0.9 7.5 35.3 10.8 25.8 8.2 1.3 0.8 2.2 11.8 1.6 28.4 31.9 1.1 11.0 0.0 29.1 16.6 5.3 105.3 6.0 0.2 28.1 233.5 8.9 1.3 2.8 13.1 0.5 6.4 0.4 2.3 0.5 0.6 0.4 3.8 16.9 24.4 15.0 PDHA1 PDHA ENSG00000131828 "Pyruvate dehydrogenase E1 subunit alpha 1" P08559 X 19343893-19361718 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 508.8;tongue: 770.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 479.9;Distal tubular cells: 354.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria "Intracellular and membrane" NA NA 100000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA047487: AB_2680066, HPA047864: AB_2680190, HPA063053: AB_2684931" "unprognostic (5.71e-3)" "unprognostic (2.46e-3)" "unprognostic (5.71e-2)" "unprognostic (3.36e-3)" "unprognostic (3.12e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-2)" "unprognostic (4.28e-1)" "unprognostic (1.01e-1)" "unprognostic (7.01e-3)" "unprognostic (6.90e-2)" "unprognostic (8.68e-2)" "prognostic favorable (1.13e-7)" "unprognostic (3.72e-2)" "unprognostic (3.03e-1)" "unprognostic (1.92e-2)" "unprognostic (9.06e-2)" 93.0 69.0 62.1 37.9 66.9 88.1 63.1 66.2 91.5 55.9 84.4 112.6 87.0 53.1 78.9 76.8 49.1 29.3 508.8 68.2 67.0 174.1 118.3 47.2 36.6 64.5 62.7 50.6 83.4 161.0 48.7 43.1 65.0 48.4 104.4 90.1 109.7 63.4 459.0 60.9 82.1 51.8 59.6 49.3 121.8 24.0 67.4 52.3 64.5 770.2 59.1 61.7 56.1 71.1 124.9 151.4 107.9 114.2 102.3 77.7 131.6 83.8 74.6 170.2 130.7 216.6 78.2 212.2 60.6 102.0 226.7 159.0 334.2 145.8 178.1 70.1 186.1 104.8 264.0 194.2 107.8 170.3 82.8 100.9 132.8 157.3 154.4 85.6 105.3 129.8 94.2 87.2 120.7 164.5 142.7 173.5 110.0 227.4 261.7 145.2 180.9 260.3 298.0 125.1 59.7 62.6 134.1 167.8 158.1 229.8 177.1 118.1 65.4 87.6 78.6 240.9 108.6 73.3 82.0 140.5 82.4 117.2 77.4 99.9 87.4 65.3 72.3 119.9 88.9 103.4 69.4 79.5 115.7 82.1 67.7 72.0 15.5 98.1 109.1 76.9 84.4 89.6 62.1 66.9 66.2 91.5 68.2 67.0 64.5 62.7 65.0 59.6 67.4 71.1 34.1 44.8 44.4 18.6 30.7 29.8 59.7 135.4 25.0 59.0 37.0 29.3 479.9 87.2 74.8 152.6 33.3 105.0 32.5 73.0 354.1 88.8 2.5 41.2 33.7 36.8 41.9 55.8 21.2 59.8 120.7 49.2 49.5 36.9 42.6 39.7 18.2 76.3 73.2 25.2 24.6 64.4 71.2 26.8 30.5 4.1 35.4 32.5 56.9 9.4 40.8 49.0 26.8 13.0 11.5 47.4 52.5 40.6 43.3 47.1 88.6 213.7 33.1 69.1 32.9 37.5 51.7 51.1 25.3 45.2 33.4 133.4 31.6 25.4 130.3 55.8 PDK3 ENSG00000067992 "Pyruvate dehydrogenase kinase 3" Q15120 X 24465270-24550466 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 71.6;Excitatory neurons: 92.8;Inhibitory neurons: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046583, HPA072492" Approved Supported Nucleoli,Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Nucleoli "HPA046583: AB_2679707, HPA072492: AB_2686526" "unprognostic (5.41e-3)" "unprognostic (5.43e-3)" "unprognostic (5.35e-3)" "unprognostic (3.40e-1)" "unprognostic (4.05e-3)" "unprognostic (5.38e-2)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.51e-1)" "unprognostic (5.57e-2)" "unprognostic (1.35e-1)" "unprognostic (1.39e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "unprognostic (1.02e-1)" "unprognostic (2.92e-1)" "unprognostic (2.28e-2)" "unprognostic (9.43e-3)" 4.4 2.0 4.4 5.6 6.2 8.9 8.8 1.4 7.5 3.5 2.5 6.1 8.2 2.8 10.9 3.9 5.9 3.2 7.4 13.2 4.7 8.8 4.7 5.0 7.9 2.6 4.2 4.8 2.9 6.7 5.8 4.1 2.4 4.6 5.3 6.0 11.1 2.9 1.4 6.8 8.3 4.5 0.9 7.7 6.9 11.6 9.1 6.3 2.3 1.8 8.0 4.2 4.1 4.2 11.5 5.2 4.2 8.0 0.2 0.0 5.0 3.4 2.4 4.1 6.9 0.5 13.9 10.4 2.3 0.8 11.6 2.1 12.3 8.4 10.4 9.7 6.0 5.3 6.1 3.3 1.4 4.6 5.8 0.9 3.6 1.1 1.2 0.5 6.8 10.9 0.9 16.5 0.5 20.9 9.4 6.0 8.1 12.2 5.6 5.0 8.0 17.3 4.1 21.4 2.6 4.0 17.9 8.0 5.5 7.3 9.6 1.9 0.1 3.3 3.6 5.8 4.2 11.0 8.9 12.9 8.7 7.7 6.4 13.3 15.4 37.9 11.8 19.6 16.5 7.5 9.1 10.3 12.2 7.3 7.6 8.6 57.6 13.3 18.8 3.5 8.3 12.4 4.4 6.2 1.4 7.5 13.2 4.7 2.6 4.2 2.4 0.9 9.1 4.2 3.9 3.2 2.0 19.6 15.2 4.6 9.5 13.5 30.1 3.5 11.1 8.1 6.6 1.5 5.2 1.8 0.0 5.5 16.6 4.2 3.9 4.3 71.6 2.1 2.9 3.8 4.2 14.3 92.8 5.1 32.1 4.9 5.6 2.8 5.7 4.9 5.3 5.3 15.0 8.4 78.0 2.9 10.2 19.8 7.4 35.9 3.7 17.4 16.0 35.6 10.3 3.7 25.7 19.6 14.0 2.1 0.3 5.7 19.0 5.9 13.3 14.2 2.4 3.5 0.0 2.0 10.6 10.2 8.3 6.8 4.4 17.8 18.2 9.7 4.1 8.4 PDLIM3 ALP ENSG00000154553 "PDZ and LIM domain 3" Q53GG5 4 185500660-185535507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "skeletal muscle: 4781.7;tongue: 1519.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 228.9;Ductal cells: 332.7;Melanocytes: 124.5;Peritubular cells: 196.0;Skeletal myocytes: 428.3;Smooth muscle cells: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 115.6;RH-30: 26.9;U-266/70: 111.2;U-266/84: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004749 Enhanced Supported Cytosol NA NA 240000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" Cytosol "HPA004749: AB_1855150" "unprognostic (2.75e-1)" "unprognostic (3.85e-2)" "unprognostic (3.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.08e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.15e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (9.46e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.97e-7)" "unprognostic (1.64e-3)" "unprognostic (7.77e-2)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.78e-3)" 36.3 11.5 12.7 25.7 13.3 0.0 34.5 16.8 14.8 22.7 10.9 201.2 20.8 235.3 59.1 216.2 97.5 40.1 314.0 12.0 15.7 13.9 7.7 55.2 10.7 19.9 14.2 38.1 18.7 0.8 20.7 18.8 13.8 87.0 32.5 11.2 56.3 148.1 4781.7 12.1 69.0 127.6 17.9 24.5 95.8 8.2 14.6 4.1 32.7 1519.6 26.2 141.1 40.8 14.2 0.0 0.0 0.9 0.0 0.3 0.0 0.8 0.0 0.0 0.3 1.0 1.2 0.4 0.0 0.0 0.0 6.0 0.0 0.0 0.2 0.0 0.0 15.1 0.0 0.8 4.7 13.5 0.0 0.0 8.7 0.0 2.6 0.0 12.3 9.1 0.0 0.0 0.0 115.6 0.0 0.0 0.1 2.4 0.0 1.0 0.0 26.9 0.3 0.0 0.0 17.6 13.3 0.0 0.0 7.3 2.8 0.6 0.0 7.9 0.0 7.6 0.1 7.1 111.2 34.8 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 13.3 16.8 14.8 12.0 15.7 19.9 14.2 13.8 17.9 14.6 14.2 22.4 9.6 6.0 37.2 2.6 8.9 11.4 0.7 12.5 12.1 72.8 105.7 228.9 5.7 2.2 0.0 12.5 2.5 0.6 0.2 0.0 332.7 0.4 1.4 0.8 39.0 3.5 0.0 2.5 16.7 2.7 82.9 1.1 1.1 0.0 1.3 67.5 0.9 1.6 5.0 0.5 0.5 2.0 1.8 11.7 2.6 19.6 2.3 124.5 1.0 3.2 36.4 0.0 6.6 2.6 31.2 0.0 196.0 7.3 12.2 0.0 0.2 3.2 44.3 105.2 428.3 131.4 4.0 12.6 2.4 7.1 12.2 2.5 2.4 0.3 3.9 PDZK1 "NHERF3, PDZD1" ENSG00000174827 "PDZ domain containing 1" Q5T2W1 1 145670852-145708148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 595.8" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 280.0;Proximal tubular cells: 1113.8" "Group enriched" "Detected in many" 4 "liver cancer: 27.6;renal cancer: 44.3" "Region enriched" "Detected in many" 7 "cerebellum: 14.7" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.2" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.2" "Group enriched" "Detected in many" 4 "RPTEC TERT1: 250.0;T-47d: 653.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005755, HPA006155, CAB008971" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" Cytosol "CAB008971: , HPA005755: AB_1855164, HPA006155: AB_1855163" "unprognostic (4.56e-3)" "unprognostic (3.07e-1)" "unprognostic (8.79e-2)" "unprognostic (4.41e-2)" "unprognostic (9.15e-2)" "unprognostic (2.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.42e-1)" "unprognostic (2.08e-1)" "unprognostic (3.27e-1)" "unprognostic (2.34e-2)" "unprognostic (9.87e-3)" "prognostic favorable (2.54e-7)" "unprognostic (9.90e-2)" "unprognostic (3.02e-1)" "unprognostic (1.00e-3)" "unprognostic (8.87e-2)" 0.6 3.5 0.7 0.5 0.9 0.6 19.6 14.7 2.0 2.4 1.9 4.7 74.8 0.7 15.8 0.2 1.0 22.0 0.4 1.0 0.5 595.8 128.1 0.3 0.7 1.4 0.8 0.3 16.6 0.0 0.6 0.5 1.8 0.3 8.2 3.0 0.4 0.8 0.3 2.6 124.9 0.8 0.4 0.7 2.8 0.6 0.8 0.3 0.3 0.1 0.2 0.2 0.3 1.5 7.6 1.2 0.8 0.8 0.3 0.4 3.0 1.2 0.3 0.2 1.0 106.6 1.0 0.7 1.3 5.9 0.5 3.4 0.2 0.6 0.6 10.3 2.0 0.9 2.8 45.7 0.0 1.1 0.9 0.3 0.7 0.4 0.2 0.8 0.0 0.4 0.8 1.6 0.8 6.0 0.7 1.4 1.2 1.5 3.6 0.4 7.3 1.6 250.0 0.3 0.6 6.7 1.7 1.8 0.2 6.4 653.8 0.9 0.5 1.3 1.3 0.9 1.1 8.8 1.2 0.6 1.0 0.6 0.5 0.1 0.1 0.0 0.7 0.1 0.2 0.6 0.2 0.8 0.0 0.4 0.2 0.3 0.1 4.2 0.0 0.5 0.0 0.3 0.7 0.9 14.7 2.0 1.0 0.5 1.4 0.8 1.8 0.4 0.8 1.5 0.2 0.0 0.0 2.0 4.1 0.1 0.0 0.1 0.0 0.4 20.2 3.3 0.5 72.9 0.0 57.0 0.0 0.0 0.9 27.4 138.9 1.2 8.6 1.1 0.5 0.4 6.6 0.0 2.8 2.0 0.1 0.5 0.5 4.9 0.0 0.2 1.1 47.9 0.2 0.0 1.9 7.8 0.0 0.9 0.3 9.0 0.0 4.9 0.0 1.9 0.0 0.3 2.1 3.0 0.7 1.5 7.4 0.0 0.0 0.1 280.0 1113.8 0.1 0.5 0.0 0.1 0.3 0.2 0.3 0.0 0.0 0.1 4.1 4.3 6.5 0.1 PDZK1IP1 "DD96, MAP17, SPAP" ENSG00000162366 "PDZK1 interacting protein 1" Q13113 1 47183582-47191044 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 1047.0" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 5516.6" "Cancer enhanced" "Detected in all" "renal cancer: 340.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "EFO-21: 148.8;RPTEC TERT1: 501.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA014907 Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nuclear speckles" "HPA014907: AB_1855166" "unprognostic (2.97e-1)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" "unprognostic (9.16e-2)" "prognostic unfavorable (6.92e-4)" "unprognostic (8.14e-3)" "unprognostic (2.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.65e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (2.64e-2)" "unprognostic (7.90e-3)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (1.75e-3)" "unprognostic (1.89e-1)" 20.9 8.2 0.6 24.6 0.8 43.2 36.4 0.4 1.2 29.9 0.7 44.4 21.6 10.7 2.9 205.9 25.7 197.6 1.4 0.5 0.7 1047.0 6.8 29.5 0.4 0.4 0.5 0.7 99.9 0.0 1.1 3.9 0.7 12.1 30.9 0.0 203.4 8.6 1.6 153.1 66.4 3.1 0.4 3.7 63.4 1.4 0.9 1.9 1.5 0.6 60.2 20.0 66.6 0.4 54.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 41.5 0.0 148.8 0.0 0.0 0.7 0.0 0.5 0.0 0.6 0.0 0.6 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 2.6 501.3 0.0 0.0 0.0 0.5 4.3 0.0 0.0 1.4 0.0 0.0 0.1 1.2 0.1 0.4 0.3 0.6 0.3 0.1 0.1 0.0 0.0 3.4 0.3 0.6 1.1 0.2 0.0 0.0 0.0 1.7 0.4 0.2 0.0 6.6 0.7 0.1 1.5 1.1 144.5 0.6 0.8 0.4 1.2 0.5 0.7 0.4 0.5 0.7 0.4 0.9 0.4 1.6 76.9 47.4 0.0 31.2 14.1 13.3 489.8 7.4 0.0 152.9 105.5 0.1 303.1 413.3 233.6 0.0 0.1 1.7 118.8 414.8 1175.8 0.0 6.1 3.3 4.5 39.6 148.4 0.0 760.0 0.0 6.6 36.7 38.1 10.8 0.2 5.0 1.7 0.3 0.0 0.0 143.3 52.9 0.3 2.1 0.0 3.4 59.3 8.8 0.0 13.6 0.6 2.1 0.0 0.0 1115.2 91.0 0.0 0.1 38.9 106.2 5516.6 147.6 0.0 0.0 0.1 28.7 0.0 0.1 30.7 54.0 0.8 22.0 0.0 150.5 68.5 PDZRN3 "KIAA1095, LNX3, SEMACAP3, SEMCAP3" ENSG00000121440 "PDZ domain containing ring finger 3" Q9UPQ7 3 73382431-73624941 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 256.0;Excitatory neurons: 183.1;Inhibitory neurons: 258.3;Microglial cells: 329.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Cell line enhanced" "Detected in many" "AF22: 32.1;ASC diff: 57.0;ASC TERT1: 29.6;BJ hTERT+: 42.0;HSkMC: 41.4;U-87 MG: 30.4" "Group enriched" "Detected in many" 4 "amygdala: 15.1;basal ganglia: 8.1;cerebral cortex: 19.5;hippocampal formation: 16.1;white matter: 7.2" "Low region specificity" "Detected in many" "HPA038822, HPA061420" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA038822: AB_10675952, HPA061420: AB_2684512" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-2)" "prognostic favorable (3.35e-5)" "unprognostic (1.09e-1)" "unprognostic (5.54e-2)" "unprognostic (8.47e-2)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "prognostic favorable (4.93e-4)" "unprognostic (8.38e-2)" "prognostic favorable (3.65e-7)" "unprognostic (8.63e-3)" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (2.86e-3)" 29.9 35.7 14.9 10.2 16.3 0.0 24.0 8.5 20.9 45.2 58.0 84.0 9.2 64.1 24.5 27.8 26.7 27.4 48.0 16.7 10.6 10.7 2.1 14.9 4.5 13.0 11.8 69.4 6.9 0.8 4.6 17.5 11.0 31.7 13.9 6.3 20.9 29.0 91.8 17.3 24.4 38.4 13.1 2.4 38.7 6.4 17.1 2.9 3.6 22.4 1.4 46.7 32.0 13.2 0.0 0.0 32.1 0.1 57.0 29.6 0.1 16.9 42.0 5.0 3.2 16.2 0.0 0.1 0.1 22.8 0.8 0.0 0.0 0.0 4.8 0.0 2.2 0.0 0.0 0.0 9.5 0.0 0.1 41.4 0.0 13.8 0.1 6.0 0.0 0.0 0.0 0.0 4.9 2.1 0.0 0.2 4.6 0.0 0.2 0.0 8.4 0.1 0.0 0.0 3.7 10.5 0.0 7.8 12.7 9.2 4.5 0.0 0.0 20.6 1.5 23.6 2.2 0.7 0.0 0.2 30.4 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 14.9 16.3 8.5 20.9 16.7 10.6 13.0 11.8 11.0 13.1 17.1 13.2 5.9 0.0 0.0 256.0 0.5 2.4 9.7 0.0 1.8 19.3 7.5 7.6 65.0 0.0 0.0 5.5 6.2 0.5 2.7 1.0 1.9 0.0 0.4 2.1 45.2 2.3 21.1 0.0 183.1 0.4 0.5 25.2 2.0 3.3 0.0 35.0 0.0 0.0 0.8 0.0 258.3 9.1 0.0 0.0 2.9 1.3 23.3 0.7 16.0 329.8 0.0 22.5 0.0 21.6 5.5 0.3 0.9 28.2 0.1 10.9 0.1 7.1 0.0 1.9 0.0 4.6 19.6 0.5 6.2 2.9 1.8 0.8 0.5 12.4 3.9 6.3 PEBP4 "CORK1, hPEBP4, MGC22776" ENSG00000134020 "Phosphatidylethanolamine binding protein 4" Q96S96 8 22713251-23000000 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 382.5;skeletal muscle: 670.8;tongue: 581.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 109.0;Alveolar cells type 2: 177.3;Cardiomyocytes: 144.7;Muller glia cells: 198.7" "Group enriched" "Detected in many" 13 "lung cancer: 11.4;prostate cancer: 23.7;thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-266/70: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025064 Uncertain "Secreted in other tissues" NA NA 190000000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "HPA025064: AB_1855174" "unprognostic (1.34e-2)" "unprognostic (2.97e-2)" "unprognostic (4.11e-2)" "unprognostic (3.66e-1)" "unprognostic (3.35e-1)" "unprognostic (4.78e-2)" "unprognostic (1.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "unprognostic (8.76e-3)" "unprognostic (9.70e-8)" "unprognostic (1.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.48e-1)" "unprognostic (4.59e-1)" 1.1 3.4 12.3 0.3 16.7 0.0 3.3 21.2 9.2 0.6 19.2 0.6 0.0 0.5 382.5 6.8 2.2 1.1 200.7 8.5 15.8 2.6 0.9 115.1 0.7 15.6 20.3 1.7 34.5 82.6 13.2 0.3 20.2 45.8 0.2 12.9 21.1 2.8 670.8 1.4 0.6 0.4 8.7 0.8 9.2 6.6 28.7 1.2 56.7 581.4 1.6 0.3 0.5 15.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 12.3 16.7 21.2 9.2 8.5 15.8 15.6 20.3 20.2 8.7 28.7 15.5 1.5 109.0 177.3 15.3 2.2 1.9 1.0 0.1 0.0 10.2 5.7 4.7 144.7 0.0 7.4 1.8 2.1 0.8 1.4 0.3 3.9 0.0 34.8 1.7 2.0 2.4 0.0 0.0 10.0 9.3 0.2 10.1 2.0 7.0 7.6 0.4 3.9 0.7 1.2 10.1 9.6 0.3 2.0 0.0 0.8 28.4 3.4 1.4 1.8 6.5 0.1 198.7 5.2 6.6 0.9 0.3 0.1 10.9 1.5 23.8 0.5 5.9 2.9 8.6 0.0 25.2 2.1 14.8 1.2 0.0 0.9 0.0 1.6 1.1 0.3 1.0 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PECR "HSA250303, SDR29C1, TERP" ENSG00000115425 "Peroxisomal trans-2-enoyl-CoA reductase" Q9BY49 2 215996329-216082955 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 160.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 91.0;Proximal enterocytes: 49.5;Proximal tubular cells: 79.1" "Cancer enhanced" "Detected in all" "liver cancer: 30.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 38.3;RPTEC TERT1: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021593, HPA022539" Enhanced Supported Peroxisomes NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA021593: AB_1855177, HPA022539: AB_1855178" "unprognostic (7.97e-2)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (2.90e-1)" "unprognostic (6.40e-2)" "unprognostic (1.16e-3)" "unprognostic (3.56e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-3)" "unprognostic (5.61e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.63e-2)" "unprognostic (1.84e-2)" "unprognostic (7.75e-2)" "unprognostic (6.64e-2)" 25.4 5.4 2.7 2.9 3.1 7.1 10.2 3.8 2.9 4.5 6.0 8.7 26.0 3.3 4.1 3.1 8.1 9.7 2.4 2.7 2.8 33.9 160.2 6.4 3.9 3.2 3.1 4.1 4.8 7.2 3.2 1.0 3.3 5.0 7.5 2.2 5.6 3.4 6.8 4.2 20.1 3.2 2.6 3.0 3.9 0.5 3.0 3.4 16.1 5.2 3.8 2.3 2.3 3.7 6.0 6.6 2.6 0.1 15.7 5.7 3.1 1.4 3.3 3.7 6.3 7.6 17.1 0.1 11.9 3.5 9.2 1.4 7.5 8.7 6.5 9.5 7.7 7.8 3.6 38.3 15.7 2.0 5.1 5.0 6.1 3.9 5.5 5.6 3.8 4.6 3.3 8.6 8.2 4.4 2.4 2.2 4.8 0.1 4.9 5.3 5.0 0.9 35.9 1.0 3.6 5.2 3.6 7.4 15.6 6.2 8.6 6.5 0.0 2.4 2.5 6.0 4.3 9.8 8.9 3.1 5.3 2.8 5.6 1.2 4.2 1.5 6.5 1.6 7.7 4.3 8.8 7.5 1.5 5.7 9.2 6.1 4.5 9.9 2.3 0.2 16.6 4.1 2.7 3.1 3.8 2.9 2.7 2.8 3.2 3.1 3.3 2.6 3.0 3.7 4.3 6.4 13.6 6.5 7.0 3.7 4.7 4.0 3.4 10.8 2.4 2.9 3.7 35.8 3.4 29.5 14.6 3.9 5.9 11.5 13.7 13.2 0.1 10.1 2.7 3.9 7.2 9.4 15.4 3.8 7.3 5.0 7.7 6.3 1.3 2.0 6.8 91.0 9.6 3.3 18.4 8.0 6.1 4.7 3.7 0.3 5.6 5.5 10.6 8.4 27.4 10.1 9.2 8.5 10.6 5.0 17.7 8.2 5.9 2.0 49.5 79.1 13.1 6.4 0.0 6.6 4.4 0.1 1.6 4.9 2.8 1.6 11.4 1.9 14.6 2.7 PEF1 PEF1A ENSG00000162517 "Penta-EF-hand domain containing 1" Q9UBV8 1 31629866-31644896 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061608 Supported Nucleoplasm,Vesicles,Cytosol NA NA 570000 "Cluster 2: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA061608: AB_2684567" "unprognostic (2.92e-2)" "prognostic favorable (3.95e-4)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-1)" "unprognostic (8.40e-2)" "prognostic unfavorable (2.88e-4)" "unprognostic (5.22e-3)" "unprognostic (1.04e-1)" "unprognostic (2.79e-2)" "unprognostic (1.60e-2)" "unprognostic (2.12e-1)" "unprognostic (1.35e-1)" "unprognostic (8.85e-3)" "unprognostic (2.38e-1)" "unprognostic (1.60e-1)" "unprognostic (2.89e-3)" 57.3 67.1 76.4 28.5 78.6 37.9 56.4 80.1 81.3 56.3 77.8 59.0 31.3 63.3 84.4 62.1 54.6 38.6 63.8 77.9 81.6 69.4 71.3 61.3 38.5 81.9 78.6 50.2 40.9 69.1 52.1 61.4 84.7 59.4 45.1 26.6 39.9 59.1 42.5 85.7 44.0 60.0 79.9 55.9 51.3 40.1 78.9 56.6 110.9 39.3 61.6 61.9 52.2 81.4 56.9 65.0 53.1 41.3 61.2 63.8 51.0 52.8 89.8 124.4 109.0 38.7 83.2 60.2 71.9 118.3 63.9 58.1 103.9 134.5 100.1 76.0 112.6 49.9 49.4 78.6 107.9 49.0 45.3 66.3 152.6 122.0 113.2 79.2 122.2 72.6 52.4 60.6 90.4 67.1 75.6 47.5 74.3 69.7 72.9 72.5 51.7 66.2 98.6 60.8 75.8 43.9 60.2 56.1 81.0 82.9 50.0 35.5 65.7 54.0 46.0 92.7 71.3 38.7 42.2 65.4 67.7 71.8 65.9 147.3 75.6 93.0 90.2 69.4 86.8 70.9 75.5 81.4 77.5 76.4 70.2 70.6 76.2 87.4 67.2 71.4 84.0 104.8 76.4 78.6 80.1 81.3 77.9 81.6 81.9 78.6 84.7 79.9 78.9 81.4 58.2 41.7 37.7 5.9 31.6 36.2 66.6 70.8 29.6 41.2 34.7 36.2 20.4 21.5 35.3 69.9 12.5 160.0 33.9 36.6 113.5 72.0 81.3 17.4 20.0 60.3 44.3 40.0 8.0 61.9 106.1 34.0 21.9 19.8 72.9 34.3 35.3 24.4 61.9 53.8 7.4 49.8 50.8 18.5 21.8 87.5 45.1 27.8 49.8 7.5 81.6 59.6 46.4 6.0 13.8 59.1 44.0 58.6 23.6 65.4 48.9 57.8 23.5 26.5 19.7 25.8 38.8 44.1 44.2 24.6 51.4 182.8 33.6 50.9 39.5 58.3 PELO ENSG00000152684 "Pelota mRNA surveillance and ribosome rescue factor" Q9BRX2 5 52787916-52804044 "Predicted intracellular proteins" "Cell cycle, Cell division, Translation regulation" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 90.7;Sertoli cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031458 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Nucleoli fibrillar center" "HPA031458: AB_10602141" "prognostic unfavorable (6.42e-4)" "unprognostic (2.44e-1)" "unprognostic (1.14e-1)" "unprognostic (2.71e-1)" "unprognostic (6.28e-3)" "unprognostic (1.71e-2)" "unprognostic (1.71e-2)" "unprognostic (6.13e-3)" "unprognostic (3.40e-1)" "unprognostic (3.72e-2)" "unprognostic (1.78e-1)" "unprognostic (4.18e-1)" "unprognostic (2.33e-2)" "unprognostic (4.56e-2)" "unprognostic (2.44e-1)" "unprognostic (1.99e-3)" "unprognostic (8.21e-2)" 9.4 17.6 5.3 5.2 5.9 8.2 7.3 5.7 5.2 6.9 4.9 11.3 4.6 9.8 7.5 6.7 7.9 6.3 10.3 5.7 6.1 9.9 10.7 11.7 6.3 5.4 6.3 5.1 5.3 7.4 6.0 11.6 5.7 6.7 3.7 4.4 4.9 6.7 12.2 8.4 6.2 9.9 5.9 12.6 7.5 4.4 6.7 4.8 7.2 8.8 3.6 8.4 6.7 5.2 18.1 18.3 8.1 14.5 14.0 10.3 7.1 20.4 22.4 19.6 23.9 18.4 13.8 5.9 36.0 22.1 29.4 14.8 11.9 17.3 16.9 6.3 16.8 6.6 15.2 15.5 42.6 12.5 7.6 13.0 17.5 22.7 18.6 16.9 11.8 8.8 8.4 18.5 17.3 14.1 13.1 7.7 6.1 3.3 19.3 4.5 10.4 17.6 14.3 8.5 13.3 10.3 10.8 13.3 11.9 13.7 12.2 4.5 11.7 11.8 11.4 12.5 26.0 7.9 10.4 7.8 22.5 11.6 10.4 22.3 5.9 7.6 4.8 3.9 5.9 4.8 6.2 5.4 6.1 3.6 5.0 4.7 19.0 4.7 2.2 2.3 4.8 4.4 5.3 5.9 5.7 5.2 5.7 6.1 5.4 6.3 5.7 5.9 6.7 5.2 49.9 9.6 7.4 0.0 9.8 46.9 53.0 24.4 14.2 16.5 12.7 18.7 12.7 17.2 20.2 9.2 2.1 35.9 10.5 8.7 35.2 31.5 65.1 18.7 23.1 50.5 10.2 8.0 0.0 25.5 90.7 36.7 9.2 27.6 1.3 11.4 40.4 18.7 20.1 8.4 0.1 16.0 14.2 6.6 23.3 9.2 17.7 15.8 7.2 0.0 7.7 15.5 6.2 0.0 0.0 24.5 6.0 12.0 14.3 36.5 12.3 29.0 16.9 11.0 85.5 13.7 56.5 22.1 13.9 14.9 35.8 53.9 23.0 18.8 11.5 38.3 PENK ENSG00000181195 Proenkephalin P01210 8 56436674-56446671 "Plasma proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 376.2;brain: 164.1;testis: 129.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 758.4;Leydig cells: 1137.9;Peritubular cells: 225.7;Spermatocytes: 274.1" "Cancer enhanced" "Detected in many" "lung cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 14.3;ASC TERT1: 8.6;BJ: 7.7;THP-1: 7.7" "Region enriched" "Detected in all" 7 "basal ganglia: 3626.9" "Region enriched" "Detected in all" 7 "basal ganglia: 923.2" "HPA013138, CAB016390" Enhanced "Secreted in other tissues" NA NA 220000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB016390: AB_2161515, HPA013138: AB_1855191" "unprognostic (6.89e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (1.17e-3)" "unprognostic (1.56e-2)" "unprognostic (3.58e-3)" "unprognostic (1.31e-2)" "unprognostic (3.60e-1)" "unprognostic (6.34e-2)" "unprognostic (5.73e-2)" "unprognostic (3.47e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.98e-3)" 8.6 376.2 29.9 4.4 164.1 0.0 4.9 45.2 45.6 9.2 0.5 23.1 1.1 8.1 0.0 1.4 7.6 12.5 25.6 2.7 74.0 0.2 0.2 3.7 0.1 81.4 15.9 29.7 1.1 0.0 17.1 2.9 51.3 22.4 2.0 0.6 2.7 23.4 3.0 0.8 4.2 4.6 54.0 0.1 10.0 129.0 38.0 0.2 1.0 5.3 0.1 0.6 6.2 10.1 0.0 0.0 0.1 0.0 14.3 8.6 0.0 7.7 2.5 1.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 29.9 164.1 45.2 45.6 2.7 74.0 81.4 15.9 51.3 54.0 38.0 10.1 0.2 0.0 1.5 0.3 0.5 0.1 0.2 758.4 0.0 0.3 0.1 0.6 0.8 0.0 8.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 85.7 0.1 3.1 0.9 0.0 0.0 0.4 0.0 0.1 16.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.4 0.0 2.0 0.0 0.7 60.8 1137.9 1.2 0.0 1.9 0.0 0.0 0.0 0.5 0.4 0.0 0.0 225.7 0.0 0.2 0.0 0.0 3.6 0.0 6.6 1.7 1.2 274.1 19.1 0.1 0.4 0.0 0.2 3.1 0.0 0.0 PERP "dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW" ENSG00000112378 "P53 apoptosis effector related to PMP22" Q96FX8 6 138088505-138107419 "Predicted membrane proteins" "Apoptosis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 782.9;skin 1: 1115.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3312.8;Squamous epithelial cells: 3451.4;Suprabasal keratinocytes: 5828.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 555.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 39.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 39.8" "Cell line enhanced" "Detected in many" "hTCEpi: 1024.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022269 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA022269: AB_1855219" "prognostic unfavorable (5.46e-4)" "unprognostic (2.90e-1)" "unprognostic (1.94e-1)" "unprognostic (5.18e-2)" "unprognostic (2.82e-2)" "unprognostic (1.27e-1)" "unprognostic (6.28e-3)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.92e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (4.02e-2)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (1.94e-1)" "unprognostic (1.51e-2)" 27.1 9.3 7.0 9.9 7.1 1.5 131.0 7.8 8.6 201.6 13.7 40.9 50.2 23.2 47.9 782.9 61.2 37.9 53.9 6.8 8.1 21.9 93.7 27.0 3.3 9.2 7.8 6.4 33.1 40.6 13.1 38.7 8.6 60.7 38.4 8.7 295.9 46.8 5.7 1115.1 52.0 19.8 7.8 1.4 65.1 3.1 9.3 23.3 24.6 16.3 149.4 60.2 426.4 6.3 81.5 80.3 3.7 11.3 60.0 63.1 172.7 115.5 129.8 17.6 12.9 64.8 143.1 1.5 45.5 37.5 144.0 268.4 15.6 207.6 4.5 126.9 64.6 1.5 70.7 69.8 42.6 1.7 1.0 44.3 1024.8 2.2 111.8 91.7 71.3 5.8 2.4 31.3 3.0 53.4 1.5 4.6 34.4 174.6 47.1 1.5 28.6 0.9 108.2 94.0 29.3 3.7 141.2 68.7 59.6 90.7 36.4 18.4 82.6 29.4 12.1 31.7 2.1 11.1 17.4 1.3 23.0 1.5 65.5 39.8 0.0 0.0 4.3 0.0 7.6 2.0 5.3 3.8 0.0 1.0 0.6 2.3 0.3 0.1 0.0 0.0 8.9 1.3 7.0 7.1 7.8 8.6 6.8 8.1 9.2 7.8 8.6 7.8 9.3 6.3 13.9 211.5 84.2 0.7 8.1 3312.8 1415.8 1383.2 1110.4 3.3 371.4 305.0 137.7 260.2 728.5 154.5 16.7 994.5 17.6 374.8 62.6 588.0 2.1 1013.4 78.1 71.8 147.2 13.9 1.2 305.1 990.1 83.8 197.2 777.1 10.8 0.5 21.4 171.3 82.0 3.3 2.1 185.0 736.5 3.8 259.2 2.7 10.5 12.8 350.4 12.2 10.3 29.1 3.1 2.0 0.5 655.0 316.7 2.6 43.2 789.2 355.0 10.6 743.5 28.3 6.6 15.4 82.6 2.4 1.4 3451.4 5828.3 824.0 67.2 73.5 218.6 1546.6 PEX11A "MGC119947, MGC138534, PEX11-ALPHA" ENSG00000166821 "Peroxisomal biogenesis factor 11 alpha" O75192 15 89677764-89690783 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 38.7;Late spermatids: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 54.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (2.57e-4)" "unprognostic (1.40e-1)" "unprognostic (6.17e-2)" "unprognostic (6.80e-3)" "unprognostic (2.82e-2)" "unprognostic (2.38e-1)" "unprognostic (3.24e-1)" "unprognostic (2.74e-2)" "unprognostic (1.10e-2)" "unprognostic (5.44e-2)" "unprognostic (4.82e-2)" "unprognostic (1.32e-2)" 25.6 10.4 7.9 3.4 8.3 0.8 20.0 6.9 8.5 7.2 12.8 14.5 16.3 6.0 10.5 6.5 9.6 5.4 8.1 7.9 8.7 11.7 39.1 6.1 2.5 7.1 7.8 13.1 11.8 10.0 5.5 3.6 7.2 18.3 12.0 12.7 11.3 10.1 17.9 5.4 12.2 5.5 7.2 4.1 11.3 11.4 9.0 2.3 10.9 12.0 3.7 9.2 6.1 7.9 10.2 6.1 4.6 0.3 23.4 8.4 3.7 5.0 8.5 7.4 12.0 4.3 11.9 4.7 5.5 5.8 10.6 13.3 0.0 7.6 8.5 7.5 16.8 7.1 7.2 6.0 16.8 4.7 2.4 10.4 9.2 4.3 7.1 5.8 5.2 4.6 0.1 1.8 5.6 10.2 0.0 0.6 2.6 20.6 11.1 0.0 0.0 4.2 6.1 6.8 3.4 8.7 16.0 54.4 15.5 8.3 14.4 4.4 4.7 4.9 4.8 13.2 4.0 5.3 9.5 0.2 11.9 0.7 4.3 1.2 0.7 2.3 3.6 1.0 2.0 1.6 1.8 2.0 1.8 0.9 2.2 2.5 0.8 3.1 0.7 0.4 1.7 1.5 7.9 8.3 6.9 8.5 7.9 8.7 7.1 7.8 7.2 7.2 9.0 7.9 1.5 6.4 8.4 12.4 2.0 1.8 9.3 5.2 7.4 8.6 15.3 10.9 8.7 10.0 11.4 5.5 2.1 10.8 1.3 22.1 5.9 7.6 24.8 7.1 5.5 3.1 3.6 0.8 3.0 4.6 7.1 4.6 3.1 5.2 1.3 6.2 4.6 38.7 4.0 18.5 3.5 8.9 6.1 3.5 0.8 39.0 5.3 1.6 3.6 2.8 1.9 14.5 1.0 3.5 3.5 5.5 11.6 2.6 0.6 11.5 20.7 12.6 16.2 9.7 0.0 6.4 4.6 22.6 8.7 5.0 2.0 2.7 1.5 11.0 11.8 11.9 PEX16 ENSG00000121680 "Peroxisomal biogenesis factor 16" Q9Y5Y5 11 45909663-45918812 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043286 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "HPA043286: AB_10794179" "unprognostic (2.48e-1)" "unprognostic (1.95e-2)" "unprognostic (8.14e-2)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (1.53e-1)" "unprognostic (9.06e-3)" "unprognostic (9.06e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-3)" "unprognostic (1.51e-1)" "unprognostic (6.75e-3)" "unprognostic (5.72e-3)" "unprognostic (2.71e-1)" "unprognostic (1.00e-1)" "prognostic favorable (9.06e-4)" 23.4 27.1 22.3 10.9 23.8 20.3 22.2 23.4 24.4 18.2 16.6 20.6 21.3 18.7 6.3 21.3 18.9 10.1 17.0 23.0 22.7 26.7 50.2 16.2 16.6 26.2 23.6 18.3 40.0 10.1 32.0 6.7 23.2 21.7 5.1 4.4 21.6 9.7 18.1 27.2 25.3 6.0 21.9 24.5 27.6 25.8 23.6 11.8 21.8 7.5 8.6 20.1 18.0 26.0 15.0 19.9 6.7 16.8 11.0 13.2 19.4 11.6 15.2 15.5 12.0 22.6 10.7 25.6 15.0 10.9 14.7 27.2 6.9 23.0 3.7 22.4 23.6 16.7 28.8 20.1 34.8 24.9 33.8 21.3 20.1 9.4 15.1 9.1 17.0 21.9 13.4 29.6 10.7 42.0 21.3 32.5 15.1 28.7 20.0 18.4 16.8 29.4 10.0 26.5 17.0 22.7 13.3 27.1 24.5 4.2 40.4 21.1 13.6 14.8 19.0 36.9 21.5 47.1 33.1 16.2 16.2 14.7 16.2 35.3 44.1 36.8 47.9 51.0 44.9 57.0 48.9 49.6 47.8 50.5 44.4 46.7 32.2 44.9 38.6 44.7 61.1 46.1 22.3 23.8 23.4 24.4 23.0 22.7 26.2 23.6 23.2 21.9 23.6 26.0 25.1 3.2 5.4 3.9 35.7 16.6 24.4 47.6 19.4 15.7 25.9 22.4 3.8 22.8 25.1 14.7 10.4 39.9 31.9 45.8 50.9 37.3 25.9 19.7 13.8 21.5 28.1 25.9 4.8 88.7 22.2 15.7 17.9 20.3 21.0 16.2 21.8 68.6 34.2 15.2 5.1 26.5 30.5 37.7 19.7 32.6 19.3 20.0 21.4 3.7 46.6 28.8 26.8 5.0 10.6 55.9 49.2 14.3 27.1 26.1 90.5 68.1 26.4 18.0 32.9 16.8 24.4 27.2 15.4 21.6 21.0 64.0 33.0 19.9 29.6 28.2 PFKFB3 ENSG00000170525 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3" Q16875 10 6144934-6254644 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 334.6;skeletal muscle: 621.3" "Cell type enhanced" "Detected in many" "Astrocytes: 153.8;Collecting duct cells: 195.0;Langerhans cells: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 26.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 296.2;RPTEC TERT1: 181.8;T-47d: 192.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008266, CAB020795, HPA043889" Uncertain Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB020795: , HPA008266: AB_1855239, HPA043889: AB_2678717" "unprognostic (1.61e-1)" "unprognostic (5.08e-3)" "unprognostic (2.89e-2)" "unprognostic (6.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (1.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (3.30e-2)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.87e-7)" "unprognostic (1.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.74e-1)" 334.6 22.7 66.1 72.2 81.2 246.0 153.8 75.4 66.6 30.2 22.1 22.2 19.4 24.0 11.1 51.3 37.7 59.9 21.9 62.8 105.8 243.9 32.8 67.7 24.5 145.7 100.9 24.2 21.0 10.1 39.6 20.0 100.9 20.2 8.9 31.5 40.4 49.5 621.3 53.6 22.9 16.9 90.1 50.2 26.1 13.9 91.8 15.1 10.9 30.4 28.2 63.9 40.3 105.6 22.0 296.2 23.1 18.8 85.2 10.5 12.2 31.6 22.5 22.9 35.5 14.1 78.0 37.2 20.2 13.8 18.0 69.0 24.9 50.2 26.3 44.6 17.3 22.1 16.2 5.2 7.2 21.6 32.2 7.6 16.4 39.5 9.5 58.3 44.9 25.6 16.6 13.6 18.6 35.7 15.3 20.3 22.5 31.1 20.5 34.3 11.3 14.7 181.8 11.1 21.9 8.9 22.9 24.7 45.8 39.5 192.0 25.2 57.0 23.9 22.0 3.1 38.7 27.8 10.4 33.7 65.8 25.0 37.4 2.9 7.5 7.7 2.2 9.2 5.7 1.8 4.2 2.9 4.7 1.6 3.0 3.0 26.4 1.2 5.5 2.9 4.3 4.3 66.1 81.2 75.4 66.6 62.8 105.8 145.7 100.9 100.9 90.1 91.8 105.6 37.1 76.9 55.1 153.8 27.2 102.6 16.7 21.5 37.5 6.4 37.1 36.8 19.5 22.8 32.1 195.0 52.1 0.4 37.0 14.9 0.0 54.7 5.0 41.1 18.9 32.9 8.5 1.3 42.8 25.7 6.9 30.8 33.1 64.3 44.2 72.5 8.9 15.8 20.6 6.7 19.4 6.6 18.3 88.0 132.3 9.5 2.8 122.2 46.2 41.2 19.6 0.3 4.1 14.1 31.9 59.6 5.2 7.2 25.3 4.2 5.4 2.4 19.2 1.9 0.0 58.5 24.4 0.6 2.5 20.9 63.9 1.0 61.7 12.4 8.1 14.7 PGAP1 "Bst1, FLJ12377, SPG67" ENSG00000197121 "Post-GPI attachment to proteins inositol deacylase 1" Q75T13 2 196833004-196927796 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 19.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 89.6;Inhibitory neurons: 104.5;Oligodendrocyte precursor cells: 130.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.21e-1)" "unprognostic (9.15e-2)" "unprognostic (5.89e-2)" "unprognostic (3.82e-2)" "unprognostic (1.81e-1)" "unprognostic (5.55e-3)" "unprognostic (2.50e-2)" "unprognostic (6.95e-2)" "unprognostic (6.51e-2)" "unprognostic (1.41e-2)" "unprognostic (2.59e-3)" "unprognostic (9.61e-2)" "unprognostic (7.16e-3)" "unprognostic (1.21e-1)" "unprognostic (7.88e-2)" "unprognostic (9.03e-3)" "unprognostic (1.91e-2)" 3.9 8.4 10.2 1.1 11.7 2.0 3.8 8.9 12.1 3.5 4.6 3.0 3.7 3.0 3.1 3.5 2.8 1.5 3.2 7.9 19.2 1.7 1.2 4.5 1.1 6.8 15.1 9.3 4.4 2.8 9.2 3.3 7.3 3.2 2.8 13.0 2.2 2.2 1.4 12.3 4.3 2.2 4.4 1.4 2.0 1.5 17.8 1.7 2.1 1.4 1.1 3.0 3.9 5.8 1.5 0.6 15.2 8.3 6.8 4.1 2.5 1.9 1.4 1.1 1.3 0.8 1.6 1.8 2.4 2.8 2.4 2.8 4.0 4.3 1.7 9.0 5.2 1.2 4.0 4.1 1.8 2.6 2.0 3.0 3.0 1.9 2.2 7.9 6.6 5.9 0.3 3.0 4.2 0.6 2.4 3.3 7.1 2.4 3.5 3.7 3.8 0.5 2.4 13.8 12.6 10.0 1.3 1.9 2.4 9.0 1.9 1.0 7.6 5.1 2.2 2.5 2.6 2.7 1.5 2.4 3.9 1.2 5.1 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.7 0.7 0.1 0.2 0.6 0.5 0.2 0.1 0.0 0.0 0.9 0.0 10.2 11.7 8.9 12.1 7.9 19.2 6.8 15.1 7.3 4.4 17.8 5.8 9.3 3.2 2.6 37.9 12.7 34.4 13.5 21.4 30.1 43.3 5.4 5.6 6.8 2.8 6.9 25.8 25.0 37.4 4.6 5.8 0.0 1.4 8.3 11.9 14.5 9.7 38.9 3.2 89.6 3.7 9.1 15.8 14.3 4.3 4.5 8.8 4.2 4.4 6.2 13.5 104.5 13.6 8.2 1.9 14.9 4.8 14.3 3.0 7.2 23.4 1.3 17.5 3.1 130.2 58.7 0.9 8.2 15.8 8.2 11.4 12.4 1.6 16.7 41.1 6.6 12.0 33.8 11.0 8.2 23.4 30.0 15.9 18.5 8.1 24.0 11.9 PGAP2 "CWH43-N, FRAG1, MRT17, MRT21" ENSG00000148985 "Post-GPI attachment to proteins 2" Q9UHJ9 11 3797724-3826371 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "GPI-anchor biosynthesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 216.2" "Group enriched" "Detected in all" 4 "Cytotrophoblasts: 74.9;Early spermatids: 147.6;Late spermatids: 296.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063099 Approved Approved Microtubules NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Microtubules "HPA063099: AB_2684940" "unprognostic (1.94e-1)" "unprognostic (1.14e-1)" "unprognostic (2.19e-1)" "unprognostic (3.18e-2)" "unprognostic (5.13e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (3.07e-1)" "unprognostic (1.11e-1)" "unprognostic (6.44e-2)" "unprognostic (3.85e-2)" "unprognostic (4.66e-3)" "unprognostic (4.13e-2)" "unprognostic (2.17e-2)" "unprognostic (2.67e-2)" 8.9 14.9 16.4 6.4 17.5 9.5 11.5 15.9 18.2 13.7 17.0 13.9 18.4 8.3 216.2 34.9 19.2 7.6 21.7 16.6 16.3 13.9 30.9 16.2 10.4 17.8 16.6 11.2 28.9 17.6 15.1 14.2 17.2 16.7 13.3 9.2 18.4 33.4 11.4 48.0 16.0 7.6 16.3 11.3 14.1 28.5 17.3 13.1 19.4 9.5 13.5 10.9 18.8 20.9 27.1 36.3 17.2 15.8 15.2 28.9 27.3 10.9 9.4 15.6 14.2 31.1 46.6 29.0 12.3 8.0 9.4 44.1 27.6 30.2 15.5 35.5 30.9 17.7 14.7 38.4 10.7 23.0 22.0 22.8 41.9 11.6 39.3 10.2 18.0 38.4 38.4 41.8 16.6 39.9 28.0 19.3 32.4 56.7 21.5 44.0 2.0 27.8 30.0 31.6 22.7 22.5 19.7 52.0 12.3 20.1 43.2 9.6 16.5 9.9 9.2 23.8 6.8 26.2 31.3 21.6 12.9 15.3 19.1 3.0 6.4 5.9 9.1 9.2 11.0 11.4 13.2 11.3 9.7 12.7 17.3 11.8 18.2 10.7 9.2 6.6 13.3 8.8 16.4 17.5 15.9 18.2 16.6 16.3 17.8 16.6 17.2 16.3 17.3 20.9 8.4 12.8 10.6 7.5 10.6 31.7 15.1 23.3 33.6 14.1 19.2 18.0 13.7 11.5 13.0 12.9 22.9 74.9 5.2 11.4 1.9 15.6 147.6 11.7 6.6 9.0 3.0 13.2 15.4 21.3 18.4 7.6 10.2 14.7 8.8 13.4 3.6 14.6 16.0 3.3 19.1 10.5 10.2 5.0 8.0 296.8 8.7 5.5 5.4 4.7 8.9 9.3 8.2 10.6 23.0 14.2 9.3 6.8 12.2 9.1 39.8 10.2 15.2 9.5 6.6 11.0 7.2 17.7 21.6 31.1 28.6 29.3 9.4 11.8 20.1 13.0 PGAP4 "C9orf125, MGC12992, TMEM246" ENSG00000165152 "Post-GPI attachment to proteins GalNAc transferase 4" Q9BRR3 9 101473170-101533537 "Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 16 "Cardiomyocytes: 52.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;hTERT-RPE1: 28.8;OE19: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011318, HPA054041" Uncertain Approved Mitochondria NA Yes "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA011318: AB_2668482, HPA054041: AB_2682353" "unprognostic (2.58e-2)" "unprognostic (4.76e-2)" "unprognostic (5.52e-1)" "unprognostic (2.81e-3)" "unprognostic (2.72e-2)" "unprognostic (9.15e-2)" "unprognostic (1.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (3.51e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.62e-1)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (9.16e-2)" 3.9 10.3 21.5 2.2 21.3 0.5 2.4 18.9 26.2 16.6 4.5 13.4 8.4 7.1 3.7 14.4 13.7 6.8 30.4 24.9 26.1 4.7 2.4 5.4 0.4 17.9 13.4 19.5 11.1 16.6 12.3 0.6 26.1 6.9 11.2 9.9 6.1 9.4 4.8 12.0 7.6 6.7 9.6 1.6 16.0 2.8 19.2 0.9 4.2 6.1 2.4 6.4 11.9 20.3 0.0 14.6 11.3 0.0 0.3 0.2 0.0 9.8 14.1 7.0 13.8 0.7 7.8 0.0 3.2 17.9 0.8 23.1 0.0 16.1 4.2 0.0 5.8 8.1 10.3 0.0 0.5 0.0 0.0 6.2 25.5 0.0 3.8 28.8 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 14.0 48.1 0.0 0.0 5.7 0.0 10.5 2.7 18.9 17.8 5.5 0.0 0.0 2.7 0.0 13.8 0.0 10.7 6.6 0.0 0.0 1.0 0.0 0.0 15.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 21.3 18.9 26.2 24.9 26.1 17.9 13.4 26.1 9.6 19.2 20.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PGBD5 "DKFZp761A0620, FLJ11413" ENSG00000177614 "PiggyBac transposable element derived 5" Q8N414 1 230314490-230426332 "Disease related genes, Predicted intracellular proteins" Transposition "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.8;pancreas: 20.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.6;Excitatory neurons: 83.3;Inhibitory neurons: 78.4;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 17.7;basal ganglia: 18.5;cerebral cortex: 35.9;hippocampal formation: 41.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 30.7;GAMG: 15.0;NTERA-2: 30.3;RH-30: 16.4;SCLC-21H: 41.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065010 Supported Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA065010: AB_2685402" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.61e-2)" "prognostic unfavorable (8.78e-5)" "unprognostic (1.44e-2)" "unprognostic (4.66e-2)" "unprognostic (4.91e-2)" "unprognostic (3.97e-1)" "unprognostic (1.15e-1)" "unprognostic (7.48e-3)" "unprognostic (2.57e-1)" "unprognostic (3.29e-2)" "unprognostic (6.69e-2)" "unprognostic (2.12e-1)" "unprognostic (3.13e-3)" "unprognostic (2.51e-1)" 0.4 9.4 17.7 0.4 18.5 0.1 0.4 1.1 35.9 18.1 0.0 1.0 0.5 4.6 0.0 1.2 4.9 1.7 13.1 41.8 0.0 1.0 3.1 1.3 0.5 0.9 0.0 0.3 20.3 1.3 5.8 2.1 1.4 0.8 0.7 6.9 5.2 0.7 2.6 0.7 0.5 2.4 0.0 2.2 1.1 5.2 0.1 3.0 5.2 5.1 4.6 0.9 2.6 6.6 0.0 0.0 7.6 0.1 0.1 0.0 0.6 0.5 0.0 0.2 0.0 6.8 0.0 30.7 2.8 0.1 15.0 5.7 2.4 0.0 0.0 0.1 2.6 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.2 1.5 0.3 6.2 30.3 0.0 0.2 0.0 16.4 4.9 3.5 0.0 41.4 7.7 1.0 0.1 0.4 0.6 0.4 10.5 0.0 0.0 2.5 0.0 2.5 12.7 10.3 0.0 0.1 2.6 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 17.7 18.5 1.1 35.9 41.8 0.0 0.9 0.0 1.4 0.0 0.1 6.6 0.3 0.0 1.9 18.9 0.3 0.1 0.7 0.1 0.0 26.6 1.3 0.6 9.0 4.3 0.4 0.0 20.9 0.1 0.3 0.4 0.0 10.3 0.9 1.4 3.0 0.3 9.1 0.0 83.3 5.8 0.2 0.8 0.0 2.9 10.8 1.9 0.4 4.1 11.5 21.9 78.4 0.4 0.0 3.8 0.3 0.9 0.0 0.9 1.8 4.7 0.1 2.8 0.0 16.1 48.0 5.5 0.3 0.0 0.0 2.1 0.0 0.8 0.9 10.8 0.0 6.4 0.8 0.7 1.8 0.0 0.0 0.3 0.5 2.8 0.6 1.9 PGD ENSG00000142657 "Phosphogluconate dehydrogenase" P52209 1 10398592-10420511 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Gluconate utilization, Pentose shunt" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 400.2;esophagus: 572.4" "Cell type enhanced" "Detected in all" "monocytes: 214.9;Squamous epithelial cells: 496.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1060.2;classical monocyte: 321.0;eosinophil: 1074.7;neutrophil: 332.6" "Group enriched" "Detected in all" 5 "granulocytes: 1074.7;monocytes: 321.0" "Cell line enhanced" "Detected in all" "A549: 1445.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031314, HPA031315" Enhanced Supported Approved "Intermediate filaments,Cytosol" No No 41000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments, Cytosol" "HPA031314: AB_10610278, HPA031315: AB_2673825" "unprognostic (4.65e-2)" "unprognostic (2.58e-1)" "unprognostic (8.65e-2)" "unprognostic (9.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.90e-2)" "unprognostic (2.83e-1)" "unprognostic (1.40e-2)" "unprognostic (4.92e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" 115.8 51.0 49.5 59.8 49.2 400.2 89.0 52.9 49.3 75.9 52.5 52.9 91.6 23.1 41.9 572.4 30.0 94.2 34.3 47.4 54.3 53.2 81.3 88.5 38.1 57.0 54.6 35.7 32.0 52.7 43.8 47.4 55.4 30.4 46.3 49.1 133.7 22.9 34.7 50.0 70.7 35.0 49.7 110.4 61.4 68.3 59.2 53.6 71.8 28.2 73.8 61.8 126.9 52.0 191.5 1445.2 319.3 340.6 445.4 274.0 71.8 124.8 185.9 144.4 195.3 219.2 190.4 163.5 151.0 109.2 202.4 148.0 225.6 192.1 96.4 127.5 199.9 227.8 264.3 452.1 136.3 390.9 249.7 196.5 92.2 229.4 55.5 186.9 344.0 223.0 305.3 145.7 183.5 202.5 321.4 179.4 194.7 221.0 109.1 252.7 298.1 312.2 199.6 105.5 178.0 154.1 99.1 153.5 137.5 196.7 173.3 308.5 369.3 81.1 149.6 98.3 134.5 111.6 256.0 323.5 175.1 393.9 73.6 1060.2 321.0 1074.7 23.2 137.7 26.5 33.1 21.4 20.8 144.6 23.3 21.1 22.3 332.6 19.7 105.6 98.7 23.1 225.0 49.5 49.2 52.9 49.3 47.4 54.3 57.0 54.6 55.4 49.7 59.2 52.0 7.4 19.2 35.0 11.8 24.9 13.0 30.8 78.0 70.6 7.8 30.4 18.5 11.0 50.1 73.2 20.2 18.8 134.6 29.8 24.3 52.8 52.1 10.9 17.8 18.6 22.6 23.4 55.7 8.6 40.3 40.7 37.5 41.8 24.5 25.9 53.9 16.1 66.2 134.6 1.7 12.6 30.2 59.0 163.8 30.9 13.4 17.1 150.9 17.8 4.7 214.9 16.5 10.3 13.6 9.0 38.7 26.7 10.5 41.9 43.5 66.6 55.1 46.2 20.2 19.7 23.4 21.5 41.5 38.4 496.0 16.6 81.3 19.4 27.3 51.7 76.1 PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297862-153310718 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 38.9;skin 1: 73.7;vagina: 21.4" "Cell type enriched" "Detected in single" 12 "Squamous epithelial cells: 4.9" "Cancer enhanced" "Detected in many" "cervical cancer: 8.9;head and neck cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "HaCaT: 3.8;HDLM-2: 1.6;hTCEpi: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA030369: AB_10603984" "unprognostic (6.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-2)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (3.88e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.1 73.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 7.6 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 PGM2 FLJ10983 ENSG00000169299 "Phosphoglucomutase 2" Q96G03 4 37826660-37862937 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Muller glia cells: 334.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040676 Uncertain Approved "Intermediate filaments" NA NA 1700000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" "Intermediate filaments" "HPA040676: AB_2677076" "unprognostic (3.11e-2)" "unprognostic (1.01e-2)" "prognostic favorable (2.14e-5)" "unprognostic (2.29e-1)" "unprognostic (3.94e-1)" "unprognostic (5.44e-2)" "unprognostic (1.70e-2)" "unprognostic (2.09e-3)" "unprognostic (5.32e-2)" "unprognostic (7.02e-2)" "unprognostic (5.37e-2)" "unprognostic (2.22e-2)" "unprognostic (6.72e-3)" "unprognostic (3.21e-2)" "unprognostic (1.88e-1)" "unprognostic (9.97e-2)" "unprognostic (1.02e-1)" 8.2 11.2 3.2 9.5 3.2 10.1 8.8 4.6 4.5 10.9 4.5 9.8 7.6 10.1 4.9 36.6 7.9 11.3 5.6 4.9 3.1 8.0 14.8 6.9 10.0 3.4 3.0 6.9 4.4 8.4 3.0 11.7 3.6 7.8 9.0 18.2 7.7 5.2 1.2 17.5 7.8 13.7 3.5 8.3 6.1 5.3 3.1 10.2 9.7 1.9 22.7 18.9 16.4 3.7 27.4 9.5 14.6 16.6 10.2 12.4 19.8 32.6 18.9 27.8 26.4 18.0 19.2 38.0 15.5 17.8 34.9 13.8 36.0 32.0 65.1 23.0 21.0 40.1 15.2 12.3 23.2 44.2 26.5 17.0 36.0 22.0 18.6 16.2 41.6 31.2 53.6 6.2 24.3 15.6 49.8 49.6 17.3 19.2 15.5 35.8 23.1 14.8 15.7 52.3 31.8 10.8 17.5 23.3 12.0 19.5 21.5 45.4 37.0 19.7 24.9 27.3 67.1 14.0 38.4 40.3 10.9 56.2 32.9 19.8 27.5 67.2 9.8 22.4 11.5 9.4 8.0 11.1 31.9 5.5 7.7 9.8 33.6 28.1 18.2 7.1 14.9 17.0 3.2 3.2 4.6 4.5 4.9 3.1 3.4 3.0 3.6 3.5 3.1 3.7 16.9 0.0 8.2 5.2 13.8 14.7 14.3 32.9 17.6 7.8 12.6 6.9 4.5 14.3 23.1 3.7 0.0 31.9 11.9 10.6 5.9 16.0 0.9 9.0 12.7 22.9 7.2 8.0 8.3 11.8 37.8 10.3 5.6 14.7 12.7 56.4 42.5 9.7 37.9 6.7 5.6 9.2 4.1 24.4 15.2 2.0 8.4 24.5 5.4 4.7 46.1 334.1 13.4 8.0 0.9 14.5 6.7 9.8 10.5 17.7 6.9 10.4 9.8 16.0 13.1 5.8 23.8 0.6 2.1 42.5 32.1 79.8 14.7 19.8 12.9 20.4 PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330316-74398433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 90.1;Exocrine glandular cells: 124.5;Pancreatic endocrine cells: 140.1;Respiratory ciliated cells: 95.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 16.6;LHCN-M2: 19.9;RH-30: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056995, HPA060948" Enhanced Approved Mitochondria No No 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 1: Pancreatic cells - Digestion" Mitochondria "HPA056995: AB_2683305, HPA060948: AB_2684394" "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" "unprognostic (7.28e-3)" "unprognostic (8.91e-2)" "unprognostic (6.16e-2)" "unprognostic (1.55e-1)" "unprognostic (7.16e-6)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (5.97e-3)" "unprognostic (1.70e-2)" "unprognostic (2.98e-1)" "unprognostic (9.33e-3)" "unprognostic (3.71e-1)" "unprognostic (1.97e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-2)" 1.9 2.6 17.6 3.7 22.1 3.2 1.9 0.0 21.5 4.9 0.0 3.2 1.3 4.4 0.8 1.0 3.2 3.3 1.1 23.1 16.2 1.6 1.0 1.8 3.0 1.9 4.5 0.9 3.1 0.7 3.9 1.1 2.2 2.9 3.5 2.6 2.6 1.3 5.9 0.7 1.5 4.0 0.3 1.5 2.1 1.3 5.7 8.1 2.7 11.1 2.7 6.4 1.9 7.8 2.7 3.8 14.5 2.7 4.3 1.9 0.4 3.5 2.6 3.0 3.3 1.4 6.8 0.3 8.5 2.3 5.3 1.3 2.9 0.7 2.8 1.1 1.5 2.1 2.0 1.1 0.5 2.4 3.2 1.0 0.7 6.8 1.2 3.2 16.6 5.0 2.8 1.8 19.9 0.3 9.9 2.1 2.9 2.0 3.3 3.1 18.9 0.1 7.8 0.5 0.7 2.9 5.7 1.3 2.6 3.9 0.2 0.4 14.0 6.6 6.0 2.7 3.7 2.4 3.8 0.3 0.6 3.4 1.6 1.2 0.3 0.5 0.9 0.3 1.3 1.1 1.6 1.1 0.2 0.8 1.5 0.8 0.3 1.4 0.2 0.8 3.9 0.5 17.6 22.1 0.0 21.5 23.1 16.2 1.9 4.5 2.2 0.3 5.7 7.8 19.6 6.4 6.4 8.5 20.9 7.6 41.2 14.3 10.8 23.9 26.5 19.4 7.3 17.2 30.2 9.2 16.7 0.6 17.6 13.8 5.9 37.4 14.1 28.1 23.5 32.1 11.9 47.5 90.1 124.5 5.3 21.0 7.1 25.5 8.2 16.1 29.3 1.0 5.4 8.4 64.8 16.2 18.3 23.0 21.6 3.6 2.5 9.9 16.0 20.6 4.6 4.4 12.3 14.6 7.1 140.1 9.3 3.8 13.4 50.4 4.2 5.3 95.4 11.0 26.3 21.3 16.7 34.2 21.2 9.0 5.3 0.1 25.0 8.8 20.9 55.6 PGM5 PGMRP ENSG00000154330 "Phosphoglucomutase 5" Q15124 9 68328308-68531061 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell adhesion, Glucose metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 269.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 107.2;Endothelial cells: 36.6;Hepatic stellate cells: 39.3;Microglial cells: 124.6;Sertoli cells: 52.6;Smooth muscle cells: 35.9" "Cancer enhanced" "Detected in many" "prostate cancer: 16.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "neutrophil: 4.8" "Lineage enriched" "Detected in single" 48 "granulocytes: 4.8" "Group enriched" "Detected in some" 5 "hTERT-RPE1: 28.7;PC-3: 56.5;RH-30: 38.8;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034397, HPA046329, HPA067102" Enhanced Uncertain Cytosol NA NA 450000 "Cluster 1: Neutrophils - Mixed function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB034397: AB_1118633, HPA046329: AB_2679625, HPA067102: AB_2732758" "unprognostic (3.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.98e-3)" "unprognostic (5.75e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-4)" "unprognostic (1.22e-3)" "unprognostic (2.79e-1)" "unprognostic (5.28e-3)" "unprognostic (4.78e-2)" "unprognostic (2.28e-2)" "prognostic favorable (1.83e-5)" "unprognostic (3.04e-2)" "unprognostic (2.91e-1)" "unprognostic (2.48e-1)" "unprognostic (4.73e-2)" 28.9 61.0 3.7 12.6 4.1 0.0 21.0 5.8 3.8 51.7 3.3 269.4 15.4 154.0 40.8 98.6 96.5 19.6 126.1 3.1 4.1 11.5 5.1 14.6 5.8 4.6 4.0 19.8 2.7 5.0 4.3 5.8 4.3 159.0 34.2 8.0 6.7 214.0 37.5 11.1 72.0 132.5 4.7 10.8 65.2 3.0 4.6 2.9 13.1 30.5 2.9 216.7 40.6 4.6 0.2 0.2 0.0 0.0 0.7 0.0 0.3 8.2 6.3 3.8 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 9.2 0.0 9.4 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 28.7 0.0 0.0 0.0 0.1 0.0 4.1 0.1 0.7 0.0 0.0 56.5 0.0 38.8 1.8 1.5 0.0 0.0 0.2 0.1 47.8 2.8 1.2 0.0 0.0 0.1 0.0 5.7 0.3 0.3 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 3.7 4.1 5.8 3.8 3.1 4.1 4.6 4.0 4.3 4.7 4.6 4.6 21.6 0.0 1.7 0.7 0.2 2.3 5.6 0.0 0.6 25.3 0.2 1.5 107.2 2.8 1.8 12.9 4.2 0.0 0.1 0.1 1.9 0.1 1.8 3.7 2.8 36.6 0.0 4.0 1.4 0.0 0.2 12.4 0.0 1.1 0.0 18.7 39.3 0.1 0.1 0.0 1.7 2.7 0.0 4.0 2.8 0.5 8.1 2.1 3.6 124.6 1.0 8.3 0.0 1.0 2.3 0.1 0.1 4.9 0.0 2.1 0.8 1.2 0.8 1.9 52.6 1.7 35.9 0.1 0.2 0.4 2.4 0.0 0.6 30.0 1.6 1.5 PGRMC1 HPR6.6 ENSG00000101856 "Progesterone receptor membrane component 1" O00264 X 119236245-119244466 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 677.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 520.4;Theca cells: 907.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002877, HPA064724" Enhanced Supported "Nucleoli,Endoplasmic reticulum" NA NA 1200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" Nucleoli "HPA002877: AB_1079602, HPA064724: " "unprognostic (6.97e-2)" "unprognostic (1.99e-1)" "unprognostic (1.72e-1)" "unprognostic (4.35e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.58e-3)" "unprognostic (9.28e-2)" "unprognostic (4.66e-2)" "unprognostic (6.20e-2)" "unprognostic (3.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-3)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 108.0 171.3 97.9 37.5 102.5 25.1 106.0 83.8 115.5 135.4 96.3 98.2 109.3 154.5 273.3 57.0 149.0 56.9 38.6 102.3 127.0 235.4 677.4 62.1 27.6 97.2 109.3 93.3 40.2 113.9 59.1 44.9 126.1 127.6 87.3 80.5 71.4 200.4 15.7 53.2 131.9 85.2 106.1 41.4 77.1 46.5 112.8 33.4 89.0 27.0 29.3 77.3 65.0 116.9 165.6 102.4 196.3 227.7 414.2 196.9 127.1 243.0 281.0 126.1 155.7 124.5 196.6 47.3 259.5 253.8 147.3 128.3 216.5 102.1 168.8 50.8 248.7 53.7 88.5 141.0 69.0 88.4 27.5 204.7 56.5 153.8 79.2 93.5 82.6 55.7 57.2 28.8 150.3 176.5 66.9 64.7 515.8 179.4 170.3 78.5 123.1 68.5 168.7 123.9 182.9 81.7 178.1 291.7 98.9 188.2 67.4 56.2 64.2 87.6 127.7 312.6 233.6 29.9 59.2 51.0 238.8 138.6 170.6 21.0 20.1 20.4 8.7 19.9 11.8 5.8 12.0 12.9 17.0 5.5 12.0 10.1 9.1 8.8 18.4 12.0 13.4 50.2 97.9 102.5 83.8 115.5 102.3 127.0 97.2 109.3 126.1 106.1 112.8 116.9 109.1 125.0 91.4 16.0 19.0 94.1 131.3 67.4 81.4 199.1 110.8 95.1 17.1 120.1 76.7 73.5 68.8 88.2 25.8 170.5 68.4 93.0 4.2 119.7 264.2 81.9 57.7 37.6 36.5 73.0 138.6 153.1 50.4 122.4 40.5 197.0 66.4 520.4 51.8 65.6 58.5 85.0 81.4 35.0 51.2 9.0 172.1 111.1 103.2 15.0 26.5 109.8 18.6 108.6 91.3 68.9 144.7 181.7 22.6 118.8 375.5 295.1 105.4 92.4 105.2 99.2 111.1 68.2 77.2 69.3 87.7 62.1 32.1 907.9 137.6 127.9 PHC1 "EDR1, HPH1, RAE28" ENSG00000111752 "Polyhomeotic homolog 1" P78364 12 8913896-8941467 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, DNA-binding" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 32.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "BEWO: 141.8;NTERA-2: 492.6;SuSa: 178.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006973 Approved Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA006973: AB_1855278" "unprognostic (4.00e-2)" "unprognostic (1.79e-1)" "unprognostic (2.57e-1)" "unprognostic (1.73e-1)" "unprognostic (4.21e-3)" "unprognostic (7.46e-2)" "unprognostic (1.33e-1)" "unprognostic (1.59e-1)" "unprognostic (2.52e-1)" "unprognostic (1.47e-1)" "unprognostic (4.79e-3)" "unprognostic (1.69e-1)" "unprognostic (1.34e-2)" "unprognostic (7.55e-2)" "unprognostic (2.47e-1)" "unprognostic (9.27e-2)" "unprognostic (3.63e-2)" 20.1 18.1 22.9 17.7 21.1 7.5 23.1 26.1 21.8 46.8 31.3 32.1 6.9 42.0 13.3 20.7 44.6 15.7 20.4 21.7 21.4 24.9 6.9 21.4 16.1 20.5 22.9 47.2 25.5 26.4 75.7 14.1 19.3 31.7 9.4 40.0 23.6 20.2 16.1 10.7 21.0 22.4 19.2 22.2 22.3 43.3 20.8 28.1 44.3 10.3 14.6 28.0 26.9 19.8 6.6 11.1 46.5 43.0 13.8 14.5 141.8 6.6 13.7 11.3 14.7 7.4 10.5 17.4 5.7 11.3 17.4 5.8 12.9 15.4 15.2 60.8 7.5 22.8 14.5 7.5 15.0 12.4 38.5 18.0 8.0 18.1 18.1 36.2 13.7 19.8 4.6 6.4 11.5 8.2 15.8 22.1 492.6 2.5 3.7 25.1 31.3 0.9 12.3 29.0 9.0 32.1 10.4 23.4 17.4 178.3 3.4 12.4 7.8 20.8 34.5 13.2 9.6 12.8 8.9 24.9 9.3 6.7 14.4 0.6 0.2 0.0 0.8 1.1 0.5 1.1 1.2 1.5 0.1 0.9 1.2 0.9 0.0 0.8 2.8 1.2 0.8 0.8 22.9 21.1 26.1 21.8 21.7 21.4 20.5 22.9 19.3 19.2 20.8 19.8 11.9 16.0 19.8 48.3 7.7 2.4 5.5 4.6 9.1 24.2 10.8 11.2 0.5 11.5 13.1 9.2 27.1 5.9 10.1 0.8 1.9 5.4 26.4 20.0 17.4 11.0 11.4 9.5 36.4 5.2 11.5 11.8 5.1 10.6 19.0 15.5 8.6 2.0 4.4 16.8 44.0 2.7 4.1 5.4 3.9 17.6 14.3 6.0 7.2 12.2 3.2 17.7 7.2 23.1 13.0 4.6 1.9 12.0 3.0 4.5 0.7 5.3 19.2 36.8 0.0 15.8 12.2 17.7 25.1 10.2 2.4 5.1 11.2 8.7 2.0 4.9 PHETA1 "FAM109A, FLJ32356, IPIP27A, SES1" ENSG00000198324 "PH domain containing endocytic trafficking adaptor 1" Q8N4B1 12 111360651-111369121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 32.6;Granulosa cells: 9.6;Hofbauer cells: 10.6;Pancreatic endocrine cells: 33.8;Theca cells: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.1" "Group enriched" "Detected in many" 4 "B-cells: 1.0;dendritic cells: 3.1;monocytes: 1.9" "Cell line enhanced" "Detected in many" "Hep G2: 43.5;OE19: 34.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (2.26e-1)" "unprognostic (6.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.05e-1)" "unprognostic (6.02e-2)" "unprognostic (1.15e-3)" "unprognostic (6.18e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (5.51e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.95e-1)" "unprognostic (1.31e-1)" "unprognostic (4.90e-2)" "unprognostic (2.80e-3)" 7.3 17.1 6.3 3.6 5.5 1.6 6.8 4.9 5.8 11.2 4.5 14.9 28.6 9.8 2.2 12.6 7.8 5.2 19.3 5.0 6.5 9.8 19.5 10.9 2.2 7.1 6.2 14.0 29.0 2.9 5.1 2.5 5.9 9.4 5.4 1.1 9.5 3.6 10.2 20.0 27.9 3.5 5.4 23.2 22.7 10.9 7.0 1.2 6.5 4.6 2.0 7.1 8.6 5.4 8.5 7.4 6.2 9.5 8.5 7.4 16.5 5.4 4.7 4.2 2.2 11.7 5.7 0.2 11.5 8.2 5.9 4.6 3.3 3.5 1.8 3.4 7.6 5.7 2.7 43.5 5.0 1.1 7.4 6.1 8.8 6.3 2.0 8.3 6.3 2.8 13.4 0.6 5.2 8.0 1.4 6.8 9.7 34.3 17.6 5.6 4.2 2.5 4.3 4.7 1.4 18.6 8.4 12.8 3.7 5.2 8.7 2.1 7.6 6.2 12.4 7.2 4.2 5.5 5.0 1.0 6.2 3.8 7.1 0.0 1.2 0.2 0.3 1.9 0.4 0.2 0.1 0.1 3.1 1.0 0.0 0.4 0.0 0.3 1.9 0.3 0.0 0.9 6.3 5.5 4.9 5.8 5.0 6.5 7.1 6.2 5.9 5.4 7.0 5.4 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 5.3 3.2 0.0 0.0 0.0 3.7 0.0 1.3 1.4 0.0 3.9 6.8 0.0 2.8 5.2 1.3 0.0 0.0 0.0 32.6 5.5 1.8 0.0 4.0 0.0 9.6 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.3 0.0 0.0 7.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 1.2 0.2 8.9 0.0 0.0 PHKA2 "PHK, PYK" ENSG00000044446 "Phosphorylase kinase regulatory subunit alpha 2" P46019 X 18892298-18984114 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 42.7;Hepatocytes: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002912 Approved Approved Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA002912: AB_10961321" "unprognostic (3.90e-2)" "unprognostic (2.06e-2)" "unprognostic (5.10e-2)" "unprognostic (1.43e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.07e-2)" "unprognostic (3.42e-1)" "unprognostic (1.82e-1)" "prognostic favorable (7.68e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (2.05e-1)" "unprognostic (1.58e-2)" "unprognostic (7.16e-2)" "prognostic favorable (2.96e-5)" 12.7 9.6 4.6 6.8 6.3 15.0 7.6 6.6 5.5 9.0 6.9 6.8 12.5 10.5 6.5 6.3 9.9 8.1 12.6 5.6 5.4 6.7 34.3 6.4 7.7 6.9 5.6 16.8 15.2 8.1 12.8 10.5 6.7 9.7 6.5 10.6 9.5 7.1 7.8 8.8 10.1 6.2 5.5 9.3 8.6 9.7 6.0 12.6 10.1 14.3 7.4 6.2 8.1 7.3 11.3 10.6 6.1 10.2 8.2 7.5 16.6 4.9 4.1 7.1 7.7 11.3 7.3 13.3 3.6 6.4 11.2 10.3 11.0 12.8 7.6 6.5 11.2 15.9 17.6 13.8 5.8 15.2 19.7 12.6 8.3 8.7 12.5 11.8 7.4 13.8 5.3 8.0 5.0 12.0 16.0 25.2 7.5 5.2 11.2 12.4 12.5 14.9 4.6 5.0 5.2 8.0 14.8 15.3 6.8 20.3 18.9 8.8 13.2 9.6 5.3 10.3 7.6 7.6 6.7 10.1 5.4 8.1 5.2 4.3 3.2 7.2 2.0 3.8 2.1 1.6 1.7 1.5 2.1 1.7 1.9 1.9 5.4 3.0 2.5 1.1 2.3 1.9 4.6 6.3 6.6 5.5 5.6 5.4 6.9 5.6 6.7 5.5 6.0 7.3 6.1 9.6 12.9 27.7 5.7 6.5 5.4 6.0 8.6 11.1 8.0 7.4 20.1 12.8 5.1 9.2 10.4 16.8 3.4 9.6 0.0 7.5 7.2 6.4 11.8 7.3 4.2 14.5 15.2 5.1 17.5 5.3 4.1 7.2 1.3 42.7 20.3 57.4 8.0 5.0 19.9 7.4 4.1 18.9 3.8 5.3 7.5 10.5 5.4 13.1 8.3 17.0 7.2 16.6 16.9 6.3 12.6 7.9 7.4 6.9 12.4 4.8 4.1 13.3 0.0 7.4 5.9 7.9 7.9 8.6 4.7 10.5 7.4 12.1 10.7 3.6 PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 204.8;Leydig cells: 205.9;Oligodendrocytes: 67.3;Peritubular cells: 149.7" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cell line enriched" "Detected in some" 6 "JURKAT: 29.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" 57.8 3.5 12.2 3.1 17.7 0.2 66.1 14.3 15.1 140.6 7.9 11.6 1.5 5.7 29.0 10.6 15.0 46.4 127.7 10.1 16.1 1.5 0.7 11.4 2.2 15.3 14.2 3.4 5.6 0.9 8.4 2.4 15.8 31.3 7.9 0.0 14.0 34.2 15.1 51.7 4.5 8.4 13.4 1.3 22.1 14.7 16.4 2.4 23.2 33.6 6.0 116.1 127.6 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.9 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 29.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.8 0.6 19.7 5.7 0.0 1.3 6.4 2.2 0.5 13.5 0.0 0.5 66.1 3.3 12.2 17.7 14.3 15.1 10.1 16.1 15.3 14.2 15.8 13.4 16.4 19.3 10.9 0.0 1.5 3.3 0.7 21.5 0.1 0.0 0.6 0.0 0.4 0.4 4.5 0.0 0.6 1.8 0.0 0.0 0.4 0.0 1.9 0.1 10.8 0.1 0.2 11.0 0.0 0.0 0.1 0.0 0.0 204.8 4.1 0.1 0.0 0.0 10.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 39.6 19.0 205.9 1.9 10.6 3.7 0.0 0.0 0.0 0.0 67.3 0.1 0.0 149.7 0.6 0.1 0.0 0.2 0.0 0.0 0.0 7.7 4.2 2.4 1.3 0.4 18.5 0.1 3.5 0.3 0.0 0.2 PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640686-97676434 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB030649: , HPA076857: AB_2686817" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" 12.0 25.7 15.5 10.0 15.1 24.1 9.3 15.1 18.9 12.6 13.4 10.7 9.8 12.7 13.0 20.7 9.6 14.0 14.2 15.5 17.8 12.6 15.0 14.2 11.2 20.2 18.8 10.0 8.4 16.6 15.8 18.0 22.0 10.9 8.7 12.9 10.5 10.4 12.7 17.4 10.8 13.0 15.8 14.6 9.4 10.8 17.3 9.8 9.5 13.0 10.6 14.5 12.7 15.2 28.7 21.3 17.2 30.7 36.0 25.8 13.8 28.0 61.5 43.3 45.7 19.4 27.7 10.4 16.2 35.8 31.8 27.1 19.3 55.9 35.8 12.6 16.4 9.3 14.6 17.7 34.5 8.4 12.7 27.3 46.9 45.4 80.1 47.4 22.4 19.9 14.7 16.5 30.4 14.6 18.4 6.4 11.1 14.7 19.8 8.6 17.8 10.3 29.7 26.6 5.8 18.9 23.9 5.9 35.5 24.0 16.4 13.2 25.0 20.6 15.2 24.6 22.1 14.6 18.4 16.9 38.1 5.0 6.8 0.0 1.2 0.0 1.3 0.8 1.0 1.4 0.5 1.1 1.3 0.6 0.4 0.9 0.4 0.7 0.6 0.6 1.2 0.6 15.5 15.1 15.1 18.9 15.5 17.8 20.2 18.8 22.0 15.8 17.3 15.2 4.9 3.2 5.4 9.8 12.0 13.4 4.5 6.5 8.0 14.7 10.7 8.9 10.4 10.0 4.3 5.5 12.5 14.0 12.5 8.6 3.9 4.9 2.4 6.8 15.4 6.9 3.0 8.2 10.9 4.9 6.4 12.0 7.1 7.6 1.3 5.7 3.6 9.9 38.1 11.8 10.9 4.0 6.1 15.0 24.7 2.2 4.4 19.0 10.6 12.2 15.0 8.0 18.6 5.5 6.0 7.2 0.8 9.1 9.4 5.8 9.0 7.3 4.8 15.1 6.6 11.9 8.0 11.0 6.1 6.3 14.3 27.1 9.7 12.4 3.6 7.8 PIF1 "C15orf20, FLJ22692" ENSG00000140451 "PIF1 5'-to-3' DNA helicase" Q9H611 15 64815632-64825668 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.8" "Cell type enhanced" "Detected in many" "Early spermatids: 21.3;Erythroid cells: 17.7;Granulosa cells: 15.1;NK-cells: 15.5;Theca cells: 18.3" "Cancer enhanced" "Detected in many" "testis cancer: 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB018701 Supported Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB018701: AB_2164654" "unprognostic (1.99e-1)" "unprognostic (6.11e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.62e-1)" "unprognostic (8.33e-3)" "unprognostic (8.66e-4)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (6.68e-2)" "unprognostic (2.38e-2)" "unprognostic (3.27e-2)" "unprognostic (0.00e+0)" "unprognostic (2.96e-3)" "unprognostic (1.78e-1)" "unprognostic (9.61e-2)" "unprognostic (5.95e-2)" 0.7 1.0 0.8 2.6 0.8 3.8 0.4 0.7 1.3 0.9 0.7 2.4 1.9 0.8 0.1 3.1 0.7 0.8 0.9 0.7 1.2 0.6 0.6 1.0 4.6 1.4 1.0 0.4 0.2 0.2 0.5 0.9 1.1 1.7 1.0 0.1 0.6 0.7 0.3 1.0 2.6 1.2 0.9 4.8 1.8 2.5 1.2 3.6 0.5 0.1 3.3 1.5 1.4 0.8 7.7 8.7 21.1 8.6 3.7 4.3 7.8 7.4 3.9 7.3 5.6 14.0 12.6 9.3 3.0 3.6 6.8 20.9 21.8 6.2 2.7 14.8 8.0 10.8 28.5 10.2 1.9 4.3 8.4 2.5 0.0 3.2 2.6 1.8 7.5 13.6 7.2 18.0 7.0 6.7 4.7 17.9 17.2 9.7 6.0 9.7 7.0 13.0 4.1 4.3 8.7 5.6 5.7 6.3 3.3 9.2 7.0 4.7 5.2 4.4 22.6 7.0 14.0 14.3 14.3 9.0 4.2 18.8 6.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.8 0.7 1.3 0.7 1.2 1.4 1.0 1.1 0.9 1.2 0.8 1.2 0.0 1.1 3.6 6.5 1.9 0.8 0.6 0.0 0.5 0.6 0.6 1.9 0.0 0.1 0.0 0.0 5.1 7.5 3.2 0.0 0.0 21.3 0.4 4.4 2.3 0.0 17.7 2.6 0.0 6.5 5.6 3.6 0.7 0.0 15.1 5.3 0.5 5.8 0.0 1.0 2.4 0.0 5.1 2.0 2.3 1.5 4.5 0.0 1.9 0.1 0.8 15.5 3.5 0.1 0.2 0.1 2.2 9.7 1.1 0.2 0.1 0.1 1.2 6.6 4.2 3.5 0.8 2.0 1.6 1.0 1.1 7.5 18.3 6.2 1.3 PIGN "MCD4, PIG-N" ENSG00000197563 "Phosphatidylinositol glycan anchor biosynthesis class N" O95427 18 61905255-62187118 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 323.7;Alveolar cells type 2: 372.2;Club cells: 138.4;granulocytes: 159.0;Oligodendrocytes: 123.2;Respiratory ciliated cells: 145.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039922, HPA040374" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cytosol" "HPA039922: AB_10805597, HPA040374: AB_10794738" "unprognostic (1.93e-2)" "unprognostic (1.71e-1)" "prognostic favorable (6.51e-4)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (3.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.99e-1)" "unprognostic (1.64e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.81e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-2)" "unprognostic (1.08e-1)" "unprognostic (5.75e-2)" "unprognostic (2.71e-1)" 10.0 10.3 9.8 10.9 14.3 16.9 15.9 49.4 47.1 11.8 3.2 16.2 14.0 11.1 11.9 22.7 8.9 12.6 13.5 13.1 9.6 11.9 18.1 9.9 10.5 4.1 0.1 12.1 15.8 16.0 4.3 17.5 9.6 17.3 18.4 38.9 14.8 7.5 13.4 20.1 13.3 8.9 0.0 10.0 21.1 19.8 11.4 12.3 16.9 10.8 12.8 14.9 7.7 49.7 31.6 19.0 18.4 23.0 23.1 31.4 24.3 32.3 25.7 21.2 24.9 24.4 31.9 36.0 44.0 25.0 18.3 44.6 26.0 27.8 32.9 30.3 16.9 21.6 29.6 19.7 16.8 46.0 24.6 18.5 18.1 21.0 24.5 22.3 27.0 25.3 26.1 50.8 23.3 28.2 22.8 13.5 29.9 25.3 17.3 24.1 35.1 35.7 25.5 48.5 20.8 21.4 42.5 29.0 13.6 50.9 46.1 28.6 29.8 41.0 28.2 15.4 23.5 54.3 53.8 17.4 22.5 25.7 40.9 10.1 7.5 6.1 6.9 6.6 7.2 7.9 7.1 6.9 8.9 8.8 8.0 8.4 9.6 12.1 7.8 10.2 6.5 3.7 9.8 14.3 49.4 47.1 13.1 9.6 4.1 0.1 9.6 0.0 11.4 49.7 8.9 323.7 372.2 52.5 9.7 8.0 8.9 8.4 10.2 7.2 16.3 9.4 10.4 12.8 138.4 11.0 4.2 9.6 14.1 11.6 1.9 11.0 6.4 9.1 16.2 24.7 6.7 16.6 54.5 9.5 11.5 26.6 10.2 11.5 159.0 19.3 10.0 12.0 10.1 6.7 41.3 11.6 10.2 9.2 4.0 6.5 7.2 26.9 3.6 44.0 7.9 7.3 3.1 57.8 123.2 10.9 9.4 3.8 8.2 11.7 5.6 5.0 145.5 6.6 6.6 6.8 6.7 20.7 7.3 17.4 17.0 10.4 18.5 10.5 12.3 12.1 PIGR ENSG00000162896 "Polymeric immunoglobulin receptor" P01833 1 206928522-206946466 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2641.0;salivary gland: 1645.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7090.1;Intestinal goblet cells: 2361.1;Paneth cells: 3208.3;Proximal enterocytes: 1558.6;Undifferentiated cells: 4954.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 731.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "EFO-21: 36.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006154, CAB009454, HPA012012" Enhanced "Secreted to digestive system" NA NA 1300000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 9: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB009454: AB_2164819, HPA006154: AB_1855370, HPA012012: AB_1855371" "prognostic favorable (1.22e-5)" "unprognostic (7.42e-2)" "unprognostic (4.78e-3)" "prognostic favorable (2.57e-4)" "unprognostic (2.31e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (2.13e-1)" "prognostic favorable (5.08e-5)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (6.92e-3)" "unprognostic (3.39e-2)" 2.4 0.5 0.4 187.3 0.2 0.3 131.0 0.5 0.4 547.0 0.2 1693.4 2641.0 20.5 0.2 12.4 3.6 455.0 0.5 0.4 0.2 108.9 34.5 101.6 1.7 0.2 0.2 0.6 13.3 0.1 1.3 0.3 0.4 13.6 1222.6 0.1 1645.1 5.3 0.3 0.6 809.8 39.1 0.1 0.8 414.6 0.3 0.6 0.4 0.2 0.0 0.6 80.3 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 36.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 1.9 0.3 0.0 0.0 0.2 0.0 6.9 0.2 1.7 0.8 2.5 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.3 0.6 0.3 0.4 1.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.3 0.8 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.0 0.4 0.2 0.5 0.4 0.4 0.2 0.2 0.2 0.4 0.1 0.6 0.6 2.1 93.0 604.3 0.0 22.1 0.3 4.0 106.6 0.0 0.0 392.4 192.0 1.4 876.4 638.4 108.5 0.0 0.1 2.5 7090.1 17.6 92.5 0.0 65.9 14.6 5.4 426.4 2.7 0.0 64.5 0.0 4.7 482.1 120.1 52.0 0.0 1.8 28.0 0.4 0.0 0.0 2361.1 59.0 2.2 1.1 0.0 0.0 5.7 1.8 0.0 0.6 0.0 0.0 0.0 0.0 221.5 3208.3 0.0 0.7 53.9 1558.6 328.4 415.4 0.0 0.0 0.0 21.0 0.0 0.0 6.9 0.0 0.0 15.6 0.1 4954.6 761.3 PIK3C2B "C2-PI3K, PI3K-C2beta" ENSG00000133056 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta" O00750 1 204422628-204494724 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 70.3;RT4: 75.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030515, HPA050360" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA030515: AB_10670043, HPA050360: AB_2681104" "unprognostic (5.77e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.18e-2)" "unprognostic (3.45e-1)" "unprognostic (2.19e-3)" "prognostic unfavorable (5.42e-4)" "unprognostic (3.35e-3)" "unprognostic (3.57e-3)" "unprognostic (2.72e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (5.36e-2)" "unprognostic (1.26e-1)" "unprognostic (1.75e-1)" "prognostic favorable (1.16e-4)" 12.0 3.6 10.4 15.2 23.6 5.0 9.7 8.5 23.3 7.4 0.0 15.8 14.4 8.4 4.8 12.9 6.5 8.0 10.6 11.2 18.8 10.2 4.9 17.2 23.4 19.2 20.4 3.0 5.2 3.2 3.3 12.8 17.1 6.2 12.9 2.9 7.2 5.4 20.9 21.2 14.9 9.9 7.3 13.6 18.9 1.9 28.0 22.3 8.1 10.8 22.1 10.9 10.7 44.2 7.5 14.8 12.9 11.9 7.4 0.6 70.3 0.9 2.9 2.8 2.1 8.8 19.2 12.7 2.7 1.7 2.5 18.3 7.7 5.2 1.1 7.7 2.1 0.3 30.1 3.3 0.4 4.5 9.3 0.9 5.4 0.7 0.4 1.1 19.1 12.6 4.7 8.3 0.2 16.7 15.4 12.8 11.8 29.3 9.3 16.6 3.3 2.4 3.5 75.6 14.1 7.8 26.0 35.9 8.4 4.7 16.1 2.4 0.7 0.4 4.5 1.3 0.2 8.9 2.6 16.4 0.5 6.7 1.9 0.0 0.1 0.0 0.5 0.0 0.5 1.5 0.6 0.4 0.1 3.2 0.3 0.3 0.2 0.8 0.0 0.0 1.2 0.2 10.4 23.6 8.5 23.3 11.2 18.8 19.2 20.4 17.1 7.3 28.0 44.2 26.7 0.0 12.2 16.0 15.3 3.8 2.1 7.9 1.2 16.6 5.3 4.4 6.9 5.7 6.9 3.7 0.0 4.4 3.3 29.2 0.0 1.8 0.6 2.0 2.5 26.1 9.6 0.0 14.3 3.4 4.4 4.5 28.5 2.4 32.4 8.5 31.1 5.5 4.2 15.2 22.8 23.8 2.0 1.6 5.1 0.7 1.2 2.9 3.6 27.2 2.3 2.7 4.1 23.6 111.5 4.7 14.5 7.5 4.9 2.4 14.6 2.1 9.1 1.0 0.0 7.7 3.3 0.1 1.5 8.1 8.0 2.2 5.0 9.4 15.5 13.8 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 115.2;HMC-1: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 11.6 7.4 4.3 12.4 5.0 23.7 11.9 8.6 8.6 12.4 14.4 17.8 17.8 8.2 7.0 18.0 12.1 10.3 15.8 5.4 4.4 26.4 11.0 11.2 12.3 5.1 3.3 9.2 22.3 19.3 2.7 18.6 6.1 15.0 18.1 23.0 19.8 12.0 19.5 23.7 17.9 9.1 3.5 10.8 13.0 8.0 4.0 17.0 43.2 13.2 13.2 9.9 5.4 7.9 64.1 21.9 11.7 9.4 10.6 13.0 79.2 14.2 14.5 15.1 16.7 26.0 25.2 25.0 38.0 13.7 29.1 27.5 15.1 24.1 27.3 31.8 12.5 115.2 14.8 17.3 11.8 30.1 185.1 12.4 17.6 10.2 21.9 26.4 21.5 12.3 43.0 19.0 18.1 28.6 17.8 20.7 16.6 49.2 19.5 11.5 12.2 19.6 24.5 35.5 9.8 7.4 37.6 18.0 56.2 34.7 44.8 73.0 20.3 8.4 11.7 21.2 21.1 30.3 22.1 23.7 22.8 27.7 14.0 4.4 5.1 6.9 2.4 2.8 1.6 2.8 2.8 1.8 5.9 2.6 3.5 2.4 6.4 0.8 2.8 1.0 1.5 2.0 4.3 5.0 8.6 8.6 5.4 4.4 5.1 3.3 6.1 3.5 4.0 7.9 19.7 9.6 21.3 40.1 12.1 19.1 18.7 12.5 14.2 16.2 13.1 7.7 37.3 12.8 18.3 18.4 25.0 35.5 6.9 30.3 5.9 11.1 1.1 18.3 4.0 13.9 16.3 8.0 96.5 19.4 61.1 7.3 21.4 18.8 14.5 6.7 9.7 19.1 14.4 21.9 92.4 17.1 4.1 33.3 23.1 1.7 3.7 28.1 7.2 37.5 29.5 8.9 11.3 48.2 88.2 20.0 25.9 6.8 10.2 25.8 21.9 23.4 17.4 19.5 6.6 8.6 5.9 16.0 19.9 22.1 23.3 47.9 11.6 4.2 15.1 17.5 PIMREG "CATS, FAM64A, FLJ10156, FLJ10491, RCS1" ENSG00000129195 "PICALM interacting mitotic regulator" Q9BSJ6 17 6444441-6451469 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.9" "Group enriched" "Detected in some" 6 "Fibroblasts: 5.5;Granulosa cells: 21.5;Hofbauer cells: 7.2;Smooth muscle cells: 14.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 161.8" "Region enhanced" "Detected in many" "white matter: 5.7" "Low region specificity" "Detected in single" "HPA043783, HPA049934" Uncertain Enhanced Nucleoplasm Yes Yes "Cluster 22: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA043783: AB_2678669, HPA049934: AB_2680959" "unprognostic (5.32e-3)" "unprognostic (1.14e-2)" "unprognostic (2.33e-1)" "unprognostic (4.37e-3)" "unprognostic (1.46e-1)" "unprognostic (1.24e-2)" "unprognostic (6.55e-3)" "unprognostic (1.23e-3)" "unprognostic (1.80e-1)" "unprognostic (5.88e-2)" "unprognostic (1.47e-3)" "unprognostic (1.50e-2)" "unprognostic (0.00e+0)" "unprognostic (8.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" 0.5 2.5 0.3 1.3 0.0 2.5 0.8 1.1 0.4 0.9 0.0 3.3 3.0 0.8 0.0 3.3 0.3 0.7 0.3 0.1 0.1 0.3 0.3 0.7 1.5 0.2 0.0 0.8 0.2 0.1 0.1 0.6 0.0 0.3 4.1 0.4 0.7 0.1 0.0 2.7 3.1 2.0 0.0 6.0 1.2 0.3 0.1 13.9 0.4 0.0 2.1 1.3 1.3 0.2 42.1 54.1 161.8 73.1 1.5 4.5 12.6 47.9 29.8 78.6 52.5 32.8 17.9 0.0 18.8 39.8 39.9 29.9 82.6 21.6 41.9 64.6 33.9 0.1 33.8 41.2 0.2 1.7 48.9 2.4 1.5 32.2 12.4 8.0 24.8 36.8 10.1 23.0 49.9 30.5 9.2 0.5 70.9 34.0 37.8 74.9 64.8 29.6 12.9 6.4 36.5 51.3 41.7 42.5 39.1 20.4 19.9 4.0 11.9 59.9 48.4 36.0 80.7 8.2 31.5 0.2 23.6 20.4 94.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.1 0.2 1.0 0.1 0.0 0.3 0.3 0.3 0.0 1.1 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.2 0.0 0.4 1.2 0.6 0.0 0.0 0.0 0.0 0.6 5.5 0.0 0.7 1.3 21.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 0.0 0.0 PIP "GCDFP-15, GCDFP15, GPIP4" ENSG00000159763 "Prolactin induced protein" P12273 7 143132077-143139739 "Plasma proteins, Predicted secreted proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 16791.8" "Group enriched" "Detected in many" 4 "Breast glandular cells: 1117.6;Breast myoepithelial cells: 324.2;Melanocytes: 403.8" "Cancer enriched" "Detected in many" 70 "breast cancer: 672.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 333 "T-47d: 703.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB002661, HPA009177" Enhanced "Secreted in other tissues" NA NA 66000000 "Cluster 37: B-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "CAB002661: , HPA009177: AB_1845459" "unprognostic (2.80e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-3)" "unprognostic (3.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.14e-1)" "unprognostic (3.49e-2)" "unprognostic (5.55e-1)" 9.1 3.6 0.7 0.2 4.8 0.1 3458.7 2.7 2.7 5.6 0.0 0.5 0.0 0.1 2.7 1.3 4.2 0.1 4.8 0.9 4.6 0.5 2.0 6.4 0.8 8.5 4.4 3.8 21.1 0.4 1.9 2.3 6.8 33.3 0.0 0.0 16791.8 3140.5 1.7 189.7 0.6 0.0 3.5 0.6 0.6 0.7 4.6 0.3 0.7 0.0 1.8 0.6 1.5 11.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 1.3 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 703.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.8 2.7 2.7 0.9 4.6 8.5 4.4 6.8 3.5 4.6 11.5 6.9 0.0 2.0 0.0 3.6 10.8 6.6 18.8 0.0 0.0 1117.6 324.2 0.1 0.0 48.2 1.8 0.0 0.0 7.0 0.0 0.0 9.3 0.0 0.0 0.0 3.9 0.0 0.0 0.0 2.5 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.4 0.0 1.6 0.0 0.0 1.5 403.8 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 0.0 0.0 13.1 0.0 0.1 147.1 0.0 0.0 0.0 9.2 0.0 0.0 0.0 1.7 0.0 2.5 0.0 0.0 13.7 PIP5K1B "MSS4, STM7" ENSG00000107242 "Phosphatidylinositol-4-phosphate 5-kinase type 1 beta" O14986 9 68705240-69009176 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 97.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.4;Early spermatids: 100.0;Inhibitory neurons: 270.1;Muller glia cells: 120.2" "Group enriched" "Detected in many" 4 "colorectal cancer: 10.1;pancreatic cancer: 3.4;stomach cancer: 9.4;testis cancer: 3.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "eosinophil: 34.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 34.5" "Cell line enhanced" "Detected in some" "AF22: 43.8;HEL: 17.0;Hep G2: 13.4;OE19: 73.1;U-266/70: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009687 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Vesicles "HPA009687: AB_1855391" "unprognostic (2.02e-3)" "unprognostic (1.84e-2)" "unprognostic (3.77e-2)" "unprognostic (2.72e-1)" "unprognostic (1.56e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-3)" "unprognostic (1.80e-2)" "unprognostic (1.38e-2)" "unprognostic (1.17e-1)" "unprognostic (2.98e-2)" "unprognostic (2.92e-2)" "prognostic favorable (1.03e-9)" "unprognostic (2.10e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" 4.2 11.9 5.6 6.0 5.3 16.1 4.9 18.4 8.1 6.3 97.3 31.2 34.8 7.5 1.7 1.2 6.0 4.0 32.2 12.3 10.7 7.8 0.3 12.9 2.6 7.9 11.2 1.0 8.6 13.7 6.6 6.5 6.3 3.1 29.1 38.0 16.4 9.6 2.9 2.3 30.8 2.9 4.0 2.6 26.1 24.7 11.4 1.0 1.2 5.1 3.6 3.3 2.5 3.7 0.0 0.0 43.8 0.0 0.1 0.0 8.5 0.0 0.0 0.0 0.0 4.6 0.0 3.6 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.8 17.0 0.3 13.4 0.0 0.9 4.4 0.0 2.0 0.0 0.0 0.0 0.1 0.5 0.9 9.3 0.3 1.1 0.1 0.2 2.3 73.1 1.4 1.4 0.1 0.3 0.3 3.4 0.9 0.1 0.0 0.1 0.5 1.0 0.2 0.1 0.1 0.0 0.4 0.1 0.0 17.0 3.5 2.3 0.0 3.1 0.0 5.6 0.5 34.5 0.0 0.0 0.0 4.7 0.3 0.1 0.1 5.4 0.7 0.1 1.7 0.0 0.2 1.4 1.6 0.3 5.6 5.3 18.4 8.1 12.3 10.7 7.9 11.2 6.3 4.0 11.4 3.7 3.6 35.3 34.4 28.7 19.2 0.6 3.2 0.5 0.6 5.1 4.7 3.3 61.6 2.8 2.8 5.5 2.1 21.3 0.0 127.4 27.4 1.6 100.0 12.8 13.6 3.3 37.0 53.6 84.7 14.0 1.3 3.1 40.2 27.5 5.7 3.8 1.4 0.0 3.9 0.0 270.1 32.6 14.2 1.0 1.3 47.6 2.5 5.6 5.4 60.0 2.6 120.2 0.0 80.9 6.4 5.2 46.6 1.5 43.2 2.5 39.2 1.4 6.5 3.3 26.3 2.5 32.2 39.0 4.5 0.7 0.3 8.8 2.1 0.9 29.7 9.8 PITPNA "PITPN, VIB1A" ENSG00000174238 "Phosphatidylinositol transfer protein alpha" Q00169 17 1517718-1562792 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000528 Uncertain Approved Vesicles,Cytosol NA NA 190000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" Cytosol Vesicles "HPA000528: AB_1079622" "unprognostic (1.54e-1)" "unprognostic (6.63e-2)" "unprognostic (2.43e-1)" "prognostic favorable (2.29e-4)" "unprognostic (7.88e-2)" "unprognostic (8.89e-3)" "unprognostic (2.37e-1)" "unprognostic (1.37e-1)" "unprognostic (7.33e-2)" "unprognostic (3.17e-2)" "prognostic favorable (1.80e-6)" "unprognostic (7.41e-2)" "prognostic favorable (9.35e-4)" "unprognostic (1.72e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-2)" "unprognostic (6.81e-3)" 42.5 36.8 41.7 61.0 45.4 93.6 41.7 46.6 56.2 50.7 51.0 47.2 56.7 55.3 58.8 76.6 65.9 45.4 39.1 43.8 50.5 40.0 39.0 46.9 40.4 62.4 45.4 32.1 33.9 60.8 33.1 50.2 58.4 54.2 55.6 47.6 84.1 61.7 24.7 93.2 88.9 54.3 41.9 42.4 40.5 44.8 52.2 33.2 64.7 22.7 57.1 51.9 41.8 43.0 64.9 70.5 70.5 61.0 72.1 78.8 110.7 68.9 75.8 70.6 50.9 78.7 25.7 81.8 62.4 94.0 45.4 79.5 64.2 68.4 97.0 68.3 69.2 44.7 61.4 37.0 70.6 31.1 51.6 58.9 90.6 70.5 73.1 74.4 118.4 67.1 63.3 44.9 74.8 36.5 80.1 28.5 49.3 103.4 34.1 63.8 27.2 46.9 70.5 73.5 25.2 55.2 83.2 59.1 51.4 70.5 52.2 24.7 113.8 44.8 39.5 126.4 95.5 27.2 49.8 28.8 77.4 47.9 58.4 3.7 2.4 3.2 2.1 2.7 4.0 4.3 3.1 2.8 3.5 3.1 2.9 2.6 8.0 3.7 1.9 2.7 5.2 1.7 41.7 45.4 46.6 56.2 43.8 50.5 62.4 45.4 58.4 41.9 52.2 43.0 29.3 35.3 35.0 28.7 14.1 31.0 17.5 12.0 12.0 36.4 30.0 30.2 23.9 17.2 17.1 25.8 8.4 43.4 26.9 41.2 13.7 16.0 12.0 50.5 48.4 31.4 22.1 15.6 42.4 18.5 47.3 19.1 13.3 36.5 19.0 16.8 34.6 30.2 40.5 40.4 46.3 27.7 10.2 29.9 49.7 16.8 12.5 36.4 19.6 36.5 36.6 40.2 13.4 12.1 16.0 26.0 22.9 21.8 15.7 33.0 78.0 16.3 21.7 18.4 6.6 18.8 45.1 35.8 34.7 37.8 41.8 120.0 14.9 24.7 25.3 27.0 PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697261 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1255.9;Inhibitory neurons: 330.9;Oligodendrocyte precursor cells: 281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol Nucleoplasm "HPA026563: AB_1855409, HPA031250: AB_2673808" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.14e-3)" "unprognostic (4.17e-2)" "prognostic favorable (4.85e-5)" "unprognostic (6.57e-2)" "unprognostic (6.32e-3)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "unprognostic (5.70e-2)" "unprognostic (2.31e-2)" "unprognostic (1.34e-2)" "unprognostic (9.83e-2)" "unprognostic (7.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.16e-2)" 25.7 8.9 27.2 5.6 30.1 3.8 18.6 23.5 26.9 8.7 13.2 7.6 1.5 7.8 3.8 9.8 10.9 3.8 13.3 22.7 31.2 21.8 9.8 15.1 8.8 38.4 41.0 15.2 23.1 1.8 13.7 6.0 28.2 11.9 2.2 15.0 14.1 4.4 5.4 4.9 8.7 3.5 28.7 9.4 12.6 2.5 42.7 8.4 9.0 5.0 7.4 12.0 9.2 20.1 4.2 1.0 4.5 6.8 2.8 5.1 3.9 6.0 2.9 0.8 0.4 0.0 6.4 4.6 1.4 3.6 1.7 2.0 6.7 6.0 1.1 9.3 3.0 0.7 7.6 3.4 0.7 1.4 9.8 3.6 2.2 0.9 2.5 0.5 3.2 6.5 0.3 16.9 2.3 7.0 10.9 2.8 6.6 1.8 7.7 15.2 0.9 4.2 9.7 5.4 4.7 13.0 1.7 3.3 4.1 4.8 3.0 4.7 3.7 1.8 1.0 2.4 2.9 13.2 6.2 3.7 14.4 4.6 1.6 0.7 1.4 10.3 11.1 2.6 5.7 0.5 6.9 9.2 0.9 1.3 8.2 8.3 1.7 5.2 4.1 0.1 2.8 4.1 27.2 30.1 23.5 26.9 22.7 31.2 38.4 41.0 28.2 28.7 42.7 20.1 102.6 9.6 1.1 1255.9 9.6 5.4 55.6 4.6 8.0 15.2 7.7 4.1 6.9 21.5 4.6 0.0 2.1 7.9 84.0 5.8 21.5 43.3 0.2 13.7 5.7 59.8 6.0 4.0 88.4 49.1 13.6 18.9 8.2 30.9 5.1 7.7 21.4 10.1 13.8 74.0 330.9 1.3 4.1 21.4 22.3 1.4 5.0 17.7 10.6 103.0 20.2 34.6 84.5 281.5 9.7 38.7 4.4 14.7 28.0 32.9 0.1 21.2 3.4 21.8 26.3 66.5 25.7 0.4 3.8 9.0 4.3 3.4 75.7 2.7 3.8 54.3 PKD2 "Pc-2, PC2, PKD4, TRPP2" ENSG00000118762 "Polycystin 2, transient receptor potential cation channel" Q13563 4 88007635-88077777 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Potassium transport, Transport, Wnt signaling pathway" "Calcium channel, Ion channel, Potassium channel, Voltage-gated channel" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.1;Inhibitory neurons: 148.6;Microglial cells: 95.5;Oligodendrocyte precursor cells: 178.9;Oligodendrocytes: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 137.2;BJ hTERT+: 207.1;fHDF/TERT166: 166.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004544, HPA015794, HPA055297" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" Cytosol "CAB004544: AB_672377, HPA015794: AB_1855437, HPA055297: " "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (1.22e-1)" "unprognostic (6.83e-2)" "unprognostic (9.71e-2)" "unprognostic (1.97e-1)" "unprognostic (3.17e-2)" "unprognostic (1.88e-1)" "unprognostic (8.64e-2)" "unprognostic (1.08e-1)" "unprognostic (6.59e-2)" "unprognostic (1.09e-1)" "unprognostic (1.17e-3)" "unprognostic (3.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.12e-2)" "unprognostic (2.51e-1)" 30.7 24.2 9.6 13.9 12.2 10.7 18.6 10.0 12.0 40.0 7.3 32.5 10.7 61.1 14.7 12.7 39.3 26.9 19.7 9.0 8.9 48.6 15.0 22.2 11.5 10.4 11.2 47.7 14.8 27.9 9.0 24.5 10.0 23.3 13.2 14.0 9.7 39.2 5.8 10.3 14.8 53.7 9.1 10.9 20.0 10.3 11.9 7.6 16.4 11.7 8.7 20.6 18.4 14.6 7.4 40.8 44.9 23.2 101.8 67.6 13.3 137.2 207.1 62.9 62.2 2.0 12.8 4.0 29.3 166.4 24.0 9.1 8.1 20.4 54.5 21.2 7.1 6.6 21.8 4.3 56.5 16.2 12.9 56.4 9.1 49.4 26.4 85.6 28.8 7.6 0.9 10.9 55.5 14.4 11.4 7.7 23.4 5.3 6.7 21.5 26.8 6.0 55.6 17.2 9.0 20.1 25.5 1.2 32.5 45.0 9.7 12.1 44.7 59.1 12.9 16.8 18.8 8.7 2.9 4.4 35.2 2.5 55.3 1.4 0.1 0.2 0.2 0.2 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.2 0.3 0.1 0.4 0.1 0.1 9.6 12.2 10.0 12.0 9.0 8.9 10.4 11.2 10.0 9.1 11.9 14.6 14.8 3.2 6.3 59.4 3.5 7.4 5.3 7.4 23.3 16.7 7.4 11.3 7.1 18.6 7.2 69.9 10.4 10.4 2.7 0.6 0.0 14.0 0.3 10.3 41.7 19.2 6.7 13.5 129.1 3.8 3.4 42.0 2.0 11.1 1.3 12.7 21.4 10.6 12.2 26.9 148.6 3.4 4.1 5.0 6.8 1.1 23.0 9.8 23.2 95.5 9.5 17.3 4.1 178.9 219.4 2.2 4.6 50.8 3.1 6.5 3.9 17.0 12.3 1.9 26.3 53.0 31.5 0.8 3.8 13.3 6.7 2.7 6.1 11.5 2.8 3.4 PKIA PRKACN1 ENSG00000171033 "CAMP-dependent protein kinase inhibitor alpha" P61925 8 78516340-78605267 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 1160.4;tongue: 953.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.8;Cardiomyocytes: 367.0;Excitatory neurons: 103.3;Inhibitory neurons: 78.2;Muller glia cells: 82.8;Oligodendrocyte precursor cells: 82.9" "Cancer enhanced" "Detected in many" "glioma: 15.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 21.4" "Lineage enriched" "Detected in many" 9 "T-cells: 21.4" "Cell line enhanced" "Detected in many" "HDLM-2: 63.9;HUVEC TERT2: 104.0;RT4: 100.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042791 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA042791: AB_10795761" "unprognostic (3.83e-3)" "unprognostic (1.89e-1)" "unprognostic (1.55e-2)" "unprognostic (5.59e-6)" "unprognostic (8.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.10e-3)" "unprognostic (1.65e-3)" "unprognostic (3.25e-2)" "unprognostic (2.58e-1)" "unprognostic (4.12e-1)" "unprognostic (1.00e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (5.41e-4)" "unprognostic (3.14e-1)" "unprognostic (1.38e-1)" "unprognostic (7.52e-3)" 2.5 9.5 44.4 5.6 49.3 2.7 4.1 41.4 49.2 2.2 11.9 3.5 1.2 3.1 3.0 21.5 5.3 8.2 185.9 49.8 44.0 4.7 0.2 8.6 7.6 25.4 34.3 5.8 1.4 108.1 8.0 1.6 36.0 20.3 2.8 33.7 6.2 5.3 1160.4 9.2 2.5 2.6 35.2 4.1 1.6 1.3 48.1 26.3 34.2 953.8 11.0 9.5 3.6 36.2 0.6 0.3 34.2 0.0 18.5 4.8 0.2 32.1 6.3 3.4 7.2 0.0 5.3 14.8 0.2 4.8 3.3 0.5 11.3 10.3 22.3 63.9 24.6 18.5 3.7 0.2 1.2 0.0 10.3 7.7 1.5 0.0 9.6 45.5 104.0 19.8 0.0 15.8 51.4 5.4 28.3 0.0 8.1 0.0 35.3 0.0 29.3 0.0 18.7 100.2 16.6 32.5 4.1 26.4 0.0 8.9 0.0 0.1 41.2 7.8 6.4 1.8 19.2 6.5 6.9 4.9 36.9 0.1 9.8 0.0 0.0 0.0 0.5 0.1 0.4 2.3 9.1 1.8 0.1 2.2 7.7 4.6 0.4 1.7 0.1 0.2 21.4 2.5 44.4 49.3 41.4 49.2 49.8 44.0 25.4 34.3 36.0 35.2 48.1 36.2 0.6 3.2 2.8 104.8 9.8 5.9 8.8 4.5 19.9 40.2 2.6 6.5 367.0 0.0 2.0 1.8 2.1 3.1 2.7 0.4 1.9 0.0 13.9 0.9 0.2 9.1 10.2 4.2 103.3 0.2 2.8 12.3 0.0 1.3 5.7 18.6 2.5 0.0 0.7 58.9 78.2 0.8 6.1 0.0 1.1 5.9 0.0 3.9 3.6 15.0 0.5 82.8 0.0 82.9 17.9 1.5 0.1 0.4 2.3 6.1 0.0 0.1 1.0 6.9 0.0 22.9 4.8 0.4 0.6 13.9 13.8 3.4 8.0 0.1 0.3 3.6 PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 19.6;kidney: 25.1;liver: 92.5" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Erythroid cells: 22.1;Hepatocytes: 16.3;Late spermatids: 23.0;Proximal enterocytes: 14.8;Proximal tubular cells: 48.9" "Cancer enriched" "Detected in some" 9 "liver cancer: 56.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "K-562: 107.8" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Not detected" "Not detected" "HPA006653, CAB034376, CAB034378" Enhanced Approved Cytosol No NA 5200000 "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB034376: AB_2163671, CAB034378: AB_2252321, HPA006653: AB_2667632" "unprognostic (9.16e-2)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.62e-1)" "unprognostic (7.86e-4)" "unprognostic (1.53e-2)" "unprognostic (1.08e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (4.07e-1)" "unprognostic (4.53e-2)" "unprognostic (1.96e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (6.21e-3)" 0.0 0.0 0.0 0.0 0.1 19.6 0.0 0.7 0.1 0.0 0.0 0.4 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 25.1 92.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.2 7.2 0.0 0.0 0.1 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.0 0.5 0.2 0.2 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.4 1.5 0.0 1.8 0.0 0.0 0.0 0.6 0.0 0.0 9.3 0.2 0.3 0.1 0.0 22.1 1.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.7 16.3 0.2 0.0 1.2 0.9 0.0 0.0 0.0 23.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 14.8 48.9 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980479 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.6;testis: 56.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.0;Extravillous trophoblasts: 52.0;Plasma cells: 22.9;Spermatocytes: 114.7;Spermatogonia: 46.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "T-reg: 1.3" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 1.1 1.0 0.4 6.8 0.5 27.6 0.6 1.6 1.4 2.2 0.2 3.9 2.8 0.6 0.3 11.5 0.4 0.6 0.9 0.5 0.2 0.9 1.6 2.0 8.0 0.7 0.6 0.3 1.8 0.1 1.0 3.1 0.8 1.0 1.3 17.4 1.9 0.1 2.4 4.4 4.0 1.0 0.5 5.6 3.3 56.9 0.7 9.6 0.5 0.0 4.5 0.7 3.3 0.8 84.2 57.0 22.0 31.2 0.3 0.9 64.0 65.5 15.1 40.0 38.4 45.0 49.3 54.2 29.2 7.9 24.2 106.7 15.7 20.7 7.2 71.7 56.7 27.9 52.7 40.0 0.0 31.2 73.6 0.7 1.8 24.0 6.5 5.0 8.4 57.6 80.6 87.0 13.5 127.5 83.6 88.0 37.9 39.3 34.4 93.7 51.2 100.7 7.8 17.7 42.6 46.7 31.9 77.7 23.9 12.1 44.7 56.9 7.7 53.2 69.7 77.3 68.0 67.6 54.2 94.0 19.4 40.0 61.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.3 0.4 0.5 1.6 1.4 0.5 0.2 0.7 0.6 0.8 0.5 0.7 0.8 0.0 0.0 1.1 0.0 1.9 2.5 1.3 2.1 0.6 0.4 1.5 1.3 0.6 1.5 1.6 1.8 6.2 16.0 1.3 5.0 0.0 0.8 20.0 0.6 0.8 0.8 1.8 29.0 0.4 0.6 52.0 2.5 3.1 1.9 0.0 4.5 0.0 0.4 11.8 0.0 0.2 3.6 6.1 2.1 1.8 8.6 0.3 1.9 0.0 0.0 0.7 0.2 0.0 0.0 0.3 0.6 0.3 0.4 22.9 0.7 0.3 0.1 0.2 7.1 0.0 0.1 2.6 114.7 46.1 11.2 0.6 7.4 4.2 0.5 8.6 2.0 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702503-128720916 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.1;Breast glandular cells: 15.3;Endothelial cells: 17.9;Microglial cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 78.0;REH: 42.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045390, HPA058305" Uncertain Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA045390: AB_2679308, HPA058305: AB_2683674" "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 12.6 2.7 6.1 2.6 5.8 2.6 13.2 7.3 6.8 6.3 4.7 5.1 4.7 7.6 0.6 5.2 7.0 2.3 15.9 5.0 5.2 9.0 4.1 11.1 2.1 6.1 5.9 2.8 5.3 2.2 1.8 3.3 6.0 5.4 0.9 0.1 11.5 2.0 3.6 5.4 6.2 2.8 5.4 9.5 7.0 2.6 7.2 2.8 6.9 3.4 1.1 6.9 6.3 5.3 2.9 14.1 11.3 17.2 0.1 0.3 27.7 8.7 2.7 12.6 13.0 0.1 10.1 0.1 8.4 4.7 2.6 19.0 13.8 2.1 2.9 9.0 26.0 17.1 78.0 20.5 2.1 2.1 3.0 0.6 0.7 6.8 1.9 2.7 25.1 5.0 39.6 1.9 2.3 26.9 2.6 9.2 10.5 13.1 4.1 42.4 21.3 3.8 5.3 1.7 1.9 8.5 6.6 3.5 6.5 6.1 12.3 13.6 21.9 0.1 10.3 20.0 6.7 6.2 2.9 5.7 1.6 2.2 8.0 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 6.1 5.8 7.3 6.8 5.0 5.2 6.1 5.9 6.0 5.4 7.2 5.3 27.1 0.0 2.0 0.3 1.2 1.0 1.7 1.7 3.4 0.2 15.3 3.6 1.8 4.3 2.1 0.0 0.0 2.2 2.0 1.5 0.0 1.9 0.2 2.2 1.1 17.9 0.0 5.0 0.3 2.6 6.1 1.8 5.1 4.9 0.0 5.0 9.3 0.4 1.9 0.0 0.2 1.7 0.0 0.8 2.3 0.9 1.5 0.8 0.0 13.1 1.2 0.3 4.1 0.0 0.1 3.3 1.5 0.7 1.6 1.1 2.6 0.6 0.5 0.2 0.0 0.7 1.3 2.8 6.6 2.8 1.0 1.4 1.9 1.4 2.5 1.7 PLA2G2E ENSG00000188784 "Phospholipase A2 group IIE" Q9NZK7 1 19920009-19923617 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "lymphoid tissue: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064085 Uncertain "Secreted - unknown location" NA NA "Cluster 16: Immune cells - Immune response" "HPA064085: AB_2685188" "unprognostic (9.56e-2)" "unprognostic (3.71e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134807-31140508 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid metabolism, Mast cell degranulation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 5.9;esophagus: 13.8;skin 1: 15.4;vagina: 7.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.6;Breast glandular cells: 7.5;Suprabasal keratinocytes: 17.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 15.1;AN3-CA: 15.3;NTERA-2: 7.8;SCLC-21H: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA021016 Uncertain Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Endoplasmic reticulum" "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.8 0.2 5.9 0.7 0.1 0.3 0.0 0.0 13.8 0.0 0.0 0.0 0.4 0.1 0.5 0.0 2.5 0.0 1.6 0.1 0.0 0.0 1.0 0.1 0.0 1.7 0.3 0.0 0.0 1.8 0.3 0.2 15.4 0.2 0.0 0.1 0.0 0.6 0.5 0.1 0.1 0.6 0.0 1.7 0.0 7.1 0.2 0.0 0.0 15.1 15.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.4 0.1 1.6 0.1 1.7 0.1 0.1 0.2 0.0 0.0 3.6 1.6 0.0 1.3 0.2 0.2 0.0 0.0 7.5 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 17.8 0.0 0.0 0.0 0.0 0.4 PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828949-186988981 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 87.2;seminal vesicle: 48.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.4;Glandular and luminal cells: 28.1;Microglial cells: 115.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 6.8;eosinophil: 7.8;intermediate monocyte: 8.4;myeloid DC: 7.7;non-classical monocyte: 4.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 7 "dendritic cells: 7.7;granulocytes: 7.8;monocytes: 8.4" "Cell line enhanced" "Detected in many" "HeLa: 52.4;OE19: 84.4;RPMI-8226: 73.4;U-2197: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 35000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Cytosol Vesicles "CAB010050: AB_631312, HPA050062: AB_2681002, HPA054206: AB_2682417" "prognostic favorable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" 9.9 12.7 2.4 6.3 3.4 4.8 6.5 2.8 3.7 14.5 3.2 11.9 11.1 10.2 11.7 7.5 24.9 6.2 6.3 2.4 3.3 10.8 2.1 5.9 5.3 4.4 3.5 6.4 7.6 87.2 2.0 5.8 4.0 8.8 8.1 0.8 6.3 48.3 0.5 9.5 8.2 10.5 4.1 6.6 5.3 2.8 3.1 1.5 2.6 2.1 2.9 29.1 8.4 3.9 0.0 39.7 0.2 0.0 23.8 9.5 0.0 1.5 15.1 1.8 3.2 0.3 15.5 0.0 0.0 0.0 6.8 2.8 24.6 7.4 0.8 12.5 0.6 7.6 52.4 0.0 14.7 11.1 3.8 5.4 5.0 19.5 4.0 2.4 16.5 3.4 16.7 5.9 0.0 0.0 0.0 0.0 2.1 84.4 5.1 0.0 0.0 73.4 0.1 5.4 0.2 0.0 5.9 2.0 7.3 0.7 0.8 15.0 3.3 14.3 1.9 66.3 3.2 2.3 0.0 0.0 5.3 32.4 20.7 0.2 6.8 7.8 0.0 8.4 0.2 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.6 1.1 4.0 3.1 0.0 1.7 2.4 3.4 2.8 3.7 2.4 3.3 4.4 3.5 4.0 4.1 3.1 3.9 0.6 0.0 1.1 0.3 0.2 21.4 4.3 4.6 10.2 0.2 2.9 2.9 2.3 0.0 4.9 0.0 0.0 0.1 3.2 1.6 1.9 2.1 0.9 33.4 1.7 6.6 1.2 3.0 8.1 0.0 0.1 11.2 7.1 28.1 10.8 3.3 1.1 0.2 6.6 0.0 5.8 2.6 2.0 7.9 8.3 1.3 10.5 11.5 5.4 115.2 3.7 0.0 1.0 2.0 0.4 1.7 7.3 14.7 0.0 2.3 2.0 0.3 2.3 0.5 0.0 1.2 5.0 0.6 0.3 5.2 8.9 0.0 1.0 1.2 4.8 13.4 PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981582-42051190 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 17.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 12.9;Basal keratinocytes: 18.1;Suprabasal keratinocytes: 44.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041105, HPA072562" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Cytosol" "HPA041105: AB_2677300, HPA072562: " "unprognostic (2.98e-1)" "unprognostic (5.52e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.22e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-7)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (4.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 18.1 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 5.1 0.5 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 5.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 44.9 0.0 0.1 0.0 0.2 0.7 PLA2G4F PLA2G4F/Z ENSG00000168907 "Phospholipase A2 group IVF" Q68DD2 15 42139034-42156636 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 78.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 74.5;Distal enterocytes: 21.7;Gastric mucus-secreting cells: 18.3;Glandular and luminal cells: 17.1;Suprabasal keratinocytes: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "OE19: 11.1;RT4: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042713, HPA056752" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" Vesicles Nucleoplasm "HPA042713: AB_10793982, HPA056752: AB_2683226" "unprognostic (1.99e-1)" "unprognostic (6.21e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.06e-2)" "unprognostic (2.32e-3)" "unprognostic (1.48e-2)" "unprognostic (5.85e-2)" "unprognostic (2.25e-1)" "unprognostic (4.79e-2)" "unprognostic (6.65e-2)" "unprognostic (1.21e-2)" "unprognostic (9.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" "unprognostic (1.63e-1)" 0.0 0.0 0.1 0.4 0.3 0.3 2.4 0.1 0.1 5.7 0.0 6.4 6.7 0.0 1.6 5.7 0.1 0.1 0.3 0.1 0.0 7.8 0.2 12.2 0.1 0.0 0.0 0.0 0.1 2.9 1.7 0.1 0.0 4.3 3.8 0.2 2.6 0.4 2.9 78.1 4.2 0.1 0.0 0.1 2.4 0.1 0.0 4.4 1.9 0.5 0.3 1.2 11.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 11.1 0.1 0.0 0.0 0.0 0.0 8.3 0.4 0.0 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 74.5 0.0 0.0 5.5 2.7 1.3 0.6 0.0 1.2 0.3 2.9 0.0 0.5 5.5 0.0 1.7 0.0 21.7 3.9 0.4 0.0 7.3 1.0 0.1 0.0 0.0 0.0 1.3 0.7 0.1 18.3 17.1 2.5 0.0 0.0 0.0 0.1 0.0 0.0 7.7 4.1 0.0 0.3 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.3 0.0 0.3 3.1 10.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 5.6 13.8 1.2 0.6 0.0 6.7 2.0 PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.2;placenta: 23.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 372.2;Macrophages: 140.9" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 43.4" "Group enriched" "Detected in many" 49 "dendritic cells: 14.1;monocytes: 43.4" "Cell line enhanced" "Detected in some" "NTERA-2: 1.7;PC-3: 3.4;RT4: 1.6;U-2 OS: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 7380000 290000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" 4.5 3.1 1.6 22.9 3.6 2.8 2.6 2.7 4.5 2.5 0.4 7.5 4.1 4.8 1.1 0.6 1.9 6.0 0.6 2.6 1.4 0.3 6.9 7.2 26.8 3.9 2.6 1.1 0.8 21.0 2.1 23.3 4.2 13.1 10.3 0.6 1.4 2.6 0.4 3.6 3.3 2.8 2.6 27.2 2.9 0.9 8.9 4.9 20.2 0.0 10.0 11.1 0.3 7.4 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.7 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 3.4 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.4 0.4 0.4 0.0 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.3 43.4 0.3 0.1 9.2 0.3 0.3 0.0 0.0 14.1 0.0 0.0 0.1 0.5 0.0 0.5 0.3 0.0 11.9 1.6 3.6 2.7 4.5 2.6 1.4 3.9 2.6 4.2 2.6 8.9 7.4 0.5 0.0 1.3 0.3 3.6 0.8 4.4 0.0 0.0 0.2 0.3 4.3 0.3 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.6 0.1 1.6 50.3 0.6 3.5 0.0 7.1 0.0 5.1 1.8 0.0 1.5 0.0 0.0 0.0 0.0 372.2 1.7 4.8 0.3 0.0 24.6 4.9 0.1 0.0 140.9 10.6 11.2 29.3 0.3 0.0 6.0 0.3 0.3 0.0 0.0 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.9 0.6 0.1 0.0 0.1 0.1 3.1 0.8 8.9 0.2 3.8 PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 39.1;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Excitatory neurons: 34.6;Inhibitory neurons: 43.5;Muller glia cells: 33.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 14.5;ASC TERT1: 19.5;BJ hTERT+: 16.2;hTERT-RPE1: 26.3;TIME: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" NA NA 960000 "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" 4.7 2.9 0.7 1.4 0.8 0.0 14.9 9.7 2.2 6.9 1.7 3.1 3.9 8.8 2.9 4.7 5.4 9.3 2.5 0.5 1.5 20.8 1.4 2.6 1.9 2.0 2.7 10.8 0.6 19.7 2.2 3.8 2.1 3.1 3.2 5.6 39.1 2.9 0.5 10.9 6.1 6.9 1.4 5.1 1.6 1.0 2.5 0.6 41.9 1.3 2.7 3.9 6.0 1.0 0.2 1.6 0.6 0.0 14.5 19.5 0.1 6.8 16.2 1.3 1.8 0.0 3.4 0.0 0.4 7.2 1.4 3.3 0.1 5.0 1.4 0.0 0.0 0.0 11.8 0.0 1.2 0.0 0.0 7.9 5.4 1.9 2.1 26.3 9.3 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 1.4 0.7 0.0 0.0 11.8 2.2 0.0 1.7 2.6 0.2 47.3 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.8 9.7 2.2 0.5 1.5 2.0 2.7 2.1 1.4 2.5 1.0 11.1 6.4 2.8 20.9 0.1 9.4 2.7 18.1 21.6 2.7 22.1 14.5 4.1 5.7 11.3 33.1 0.0 7.3 0.5 1.7 0.0 0.6 0.1 5.6 22.0 4.0 1.2 0.0 34.6 2.0 1.3 14.8 0.0 9.4 1.3 9.6 8.6 0.0 0.6 16.8 43.5 7.2 4.1 0.0 2.1 1.4 16.1 0.5 7.2 25.3 0.0 33.5 0.0 5.5 1.8 5.1 11.3 16.6 0.1 2.6 15.6 2.3 8.1 1.4 6.6 3.4 4.8 0.1 1.0 9.3 5.4 1.5 0.6 6.3 7.5 3.0 PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 187.7;Hofbauer cells: 105.6;Kupffer cells: 109.4;Macrophages: 116.3;monocytes: 192.8;Paneth cells: 105.9" "Cancer enhanced" "Detected in all" "testis cancer: 113.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 662.9;intermediate monocyte: 204.4;myeloid DC: 357.3;neutrophil: 443.8" "Group enriched" "Detected in all" 135 "dendritic cells: 357.3;granulocytes: 443.8;monocytes: 662.9" "Cell line enhanced" "Detected in many" "AN3-CA: 48.6;BEWO: 98.4;CAPAN-2: 245.6;MCF7: 46.3" "Not detected" "Not detected" HPA040303 Enhanced "Intracellular and membrane" NA NA 3400000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA040303: AB_2676922" "unprognostic (9.13e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-1)" "unprognostic (7.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (4.80e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.12e-1)" "unprognostic (3.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (4.99e-2)" "unprognostic (5.44e-2)" 29.4 5.6 2.1 33.7 2.5 285.9 27.8 2.4 3.7 22.4 25.9 58.8 28.2 13.5 10.6 56.3 16.6 33.1 32.6 2.1 2.4 26.3 10.6 64.0 9.2 3.5 3.2 4.4 30.0 3.2 3.4 35.9 3.2 10.2 79.2 0.8 11.9 15.3 9.9 24.8 42.6 28.1 3.1 25.2 36.6 10.0 2.8 7.8 6.1 17.2 32.7 58.5 29.6 4.8 7.1 5.0 0.5 48.6 0.3 0.0 98.4 0.2 0.0 3.0 2.4 14.1 245.6 0.0 1.4 1.0 0.4 9.4 0.0 0.0 0.5 0.0 0.1 0.0 6.4 0.0 3.8 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.1 46.3 0.1 0.2 16.5 0.7 0.3 0.1 0.1 0.5 0.7 28.9 0.0 0.4 30.2 14.8 1.9 26.5 9.0 9.6 0.0 0.5 0.4 0.0 0.6 8.7 23.7 0.2 0.0 0.1 0.4 0.4 662.9 5.8 1.0 204.4 0.6 3.6 0.5 0.4 357.3 0.8 0.7 0.7 443.8 1.7 73.5 4.1 0.9 423.2 2.1 2.5 2.4 3.7 2.1 2.4 3.5 3.2 3.2 3.1 2.8 4.8 15.5 9.6 8.6 0.3 2.9 6.8 8.8 4.9 6.8 0.0 11.9 6.6 16.5 30.0 20.4 33.1 0.0 94.5 1.5 67.8 11.7 13.1 51.8 2.5 9.1 7.2 9.1 1.7 1.6 46.5 187.7 59.6 13.3 0.9 5.1 5.9 4.6 2.9 105.6 0.0 0.9 31.3 6.1 109.4 68.6 5.8 26.1 116.3 5.4 7.5 192.8 1.6 1.0 1.5 0.2 28.6 105.9 27.8 3.6 3.8 52.8 15.7 19.0 0.2 0.0 12.0 10.4 17.4 12.0 17.8 19.9 70.3 1.6 6.1 75.2 30.1 PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108959-45133354 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 85.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 195.8;Paneth cells: 104.7;Urothelial cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA025711: AB_1855320, HPA053665: AB_2732580" "unprognostic (3.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" "unprognostic (4.14e-3)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.96e-1)" "unprognostic (9.53e-2)" "unprognostic (1.34e-3)" "unprognostic (6.21e-2)" "unprognostic (3.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "prognostic favorable (4.28e-4)" "unprognostic (3.34e-3)" 13.5 34.3 42.2 5.1 49.7 2.0 11.7 50.5 36.0 12.4 27.9 34.2 2.5 13.2 1.5 14.7 10.1 6.4 34.1 33.8 42.5 9.6 1.4 7.7 1.0 69.8 50.5 18.9 2.7 1.3 7.6 5.8 46.4 13.0 15.3 14.4 10.8 5.4 85.7 20.6 6.5 5.1 62.8 2.0 21.0 10.8 59.4 0.9 5.3 56.5 1.5 30.4 11.9 54.0 23.1 56.2 4.1 8.1 5.9 12.8 28.0 12.3 27.3 11.2 10.5 13.7 40.9 0.8 43.5 29.0 9.2 51.9 6.3 53.1 4.4 11.6 21.0 0.9 62.6 18.1 30.3 1.3 3.2 13.7 21.0 10.4 13.7 28.5 7.0 2.5 5.0 1.7 12.1 36.2 3.7 5.4 4.9 109.9 55.0 8.1 9.2 1.5 35.8 45.1 1.1 7.2 13.3 22.1 12.5 8.5 47.0 2.5 14.3 6.9 37.9 9.3 14.8 2.1 2.6 1.8 11.4 1.5 5.7 0.7 0.3 0.5 0.1 0.3 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.2 0.0 0.1 0.1 0.1 42.2 49.7 50.5 36.0 33.8 42.5 69.8 50.5 46.4 62.8 59.4 54.0 8.7 12.8 1.3 22.9 1.0 7.6 16.3 12.2 21.1 29.8 6.8 9.3 26.9 14.3 4.9 7.3 25.0 3.9 0.9 195.8 1.9 6.7 15.8 3.3 12.7 9.0 4.9 0.0 1.3 3.5 13.1 10.6 29.6 9.6 1.3 6.5 10.4 0.7 1.6 6.7 3.7 15.1 4.1 1.4 1.9 5.5 19.9 1.6 3.6 1.0 1.2 8.9 0.0 0.0 0.1 30.0 104.7 33.1 1.1 28.7 4.2 2.0 2.7 40.0 6.6 16.8 4.9 2.3 7.6 3.8 5.7 7.3 1.1 7.0 46.2 88.6 PLCE1 "KIAA1516, NPHS3, PLCE" ENSG00000138193 "Phospholipase C epsilon 1" Q9P212 10 93993931-94332823 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;Astrocytes: 69.5;Distal enterocytes: 79.6;Inhibitory neurons: 83.9;Muller glia cells: 82.7;Oligodendrocyte precursor cells: 123.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015597, HPA015598" Enhanced Supported Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA015597: AB_1855321, HPA015598: AB_1855322" "unprognostic (4.73e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.59e-3)" "unprognostic (3.01e-1)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (4.76e-3)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-3)" "unprognostic (3.56e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" "unprognostic (4.30e-2)" 3.8 2.6 4.5 2.8 4.1 0.2 2.7 3.1 5.6 8.0 7.0 12.6 4.0 9.0 5.3 1.7 4.4 2.5 12.4 3.9 4.7 8.4 0.7 7.3 0.7 3.9 4.8 3.9 14.7 0.8 4.4 2.9 4.0 3.8 7.5 7.3 2.3 5.4 4.1 1.1 5.2 4.2 3.2 6.2 8.3 2.0 5.4 0.5 9.8 6.3 0.6 5.6 5.6 4.2 4.0 6.7 1.8 1.1 0.7 3.2 1.9 2.8 0.6 0.3 0.4 5.3 1.3 0.8 1.3 2.3 1.3 2.6 2.2 0.4 0.6 0.4 2.3 0.5 4.0 0.5 0.0 0.9 0.3 1.8 0.0 1.1 0.0 6.8 0.0 0.4 0.5 0.3 4.2 0.3 0.8 0.9 0.7 7.9 5.0 0.1 3.9 0.2 0.2 10.3 0.9 1.5 3.3 3.6 0.7 4.1 3.5 0.6 0.6 3.0 5.9 2.0 4.4 0.6 0.3 0.4 3.5 1.1 2.2 0.1 0.1 0.0 0.3 0.2 0.2 0.5 0.3 0.2 0.1 0.7 0.5 0.4 0.1 0.2 0.2 0.2 0.1 0.1 4.5 4.1 3.1 5.6 3.9 4.7 3.9 4.8 4.0 3.2 5.4 4.2 8.2 70.5 5.4 69.5 7.0 8.2 9.7 6.8 2.2 12.2 3.6 3.6 34.7 4.3 12.3 0.0 0.0 3.7 2.9 79.6 1.9 1.1 20.7 26.7 18.4 9.7 1.8 0.0 3.1 6.4 2.5 15.3 29.6 10.6 0.0 7.2 4.2 1.6 0.7 6.7 83.9 9.7 4.1 2.4 5.2 5.3 12.2 1.3 7.2 5.6 1.2 82.7 4.1 123.1 2.4 4.2 54.8 23.3 0.9 7.5 11.0 2.5 10.6 18.7 6.6 30.8 37.7 3.7 8.0 1.7 7.4 1.9 4.3 3.7 41.1 10.5 PLCH1 "DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3" ENSG00000114805 "Phospholipase C eta 1" Q4KWH8 3 155375580-155745071 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.6;retina: 12.4" "Group enriched" "Detected in many" 4 "Astrocytes: 93.7;Early spermatids: 206.2;Excitatory neurons: 126.0;Inhibitory neurons: 131.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 12.3;AF22: 39.0;HEL: 10.1;NTERA-2: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036176, HPA057978" Uncertain Enhanced Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA036176: AB_10671837, HPA057978: AB_2683569" "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (2.17e-2)" "unprognostic (1.55e-2)" "unprognostic (3.50e-4)" "unprognostic (6.41e-2)" "unprognostic (2.94e-5)" "unprognostic (5.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.24e-3)" "unprognostic (4.84e-2)" "unprognostic (1.76e-2)" "prognostic favorable (3.03e-5)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-2)" 0.0 0.0 5.5 0.3 4.8 0.2 2.6 4.5 6.0 1.2 9.3 2.5 2.5 0.7 8.2 0.1 8.1 1.5 1.8 3.8 1.4 1.2 0.1 4.0 0.0 1.3 4.6 0.1 1.4 0.4 1.5 0.4 1.5 0.3 2.4 12.4 1.3 1.9 0.2 0.1 2.5 0.1 1.6 0.0 3.8 11.3 1.3 16.6 5.7 0.0 0.0 0.4 0.1 2.0 0.0 12.3 39.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.2 2.4 9.8 0.0 0.8 0.0 0.1 0.0 7.0 0.0 0.0 0.0 3.6 10.1 0.0 1.4 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.3 0.0 0.0 4.4 2.4 9.4 20.8 1.3 1.6 0.9 0.0 0.0 2.4 0.2 3.6 0.9 0.0 9.4 0.0 5.7 4.2 0.0 0.0 0.0 0.2 0.0 1.7 0.4 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 4.8 4.5 6.0 3.8 1.4 1.3 4.6 1.5 1.6 1.3 2.0 0.0 3.2 13.6 93.7 0.3 0.0 0.4 0.5 0.6 10.5 4.0 5.0 0.8 4.3 2.3 1.8 4.2 0.0 0.1 2.7 0.0 2.2 206.2 34.6 1.3 0.6 3.0 0.0 126.0 2.3 0.3 0.3 15.3 13.6 0.0 0.1 0.0 0.0 0.2 25.2 131.5 4.0 0.0 0.3 0.4 21.4 1.2 0.4 0.0 12.2 0.1 16.1 0.0 5.5 5.7 1.5 4.6 0.4 0.0 0.4 2.8 2.1 23.4 3.0 0.0 0.0 0.2 2.4 1.2 0.7 0.1 0.0 0.3 0.1 4.4 0.4 PLCH2 "KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1" ENSG00000149527 "Phospholipase C eta 2" O75038 1 2425980-2505532 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 44.8;skin 1: 59.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 102.5;Cone photoreceptor cells: 75.0;Oligodendrocytes: 37.4;Rod photoreceptor cells: 169.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HBEC3-KT: 130.9;hTCEpi: 58.9;hTERT-HME1: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072705 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA072705: AB_2732211" "unprognostic (2.06e-3)" "unprognostic (1.30e-2)" "unprognostic (1.09e-3)" "unprognostic (3.84e-3)" "unprognostic (1.99e-1)" "unprognostic (1.59e-2)" "unprognostic (7.39e-2)" "unprognostic (7.70e-2)" "unprognostic (7.58e-2)" "unprognostic (9.28e-2)" "unprognostic (2.26e-1)" "unprognostic (5.95e-2)" "unprognostic (6.61e-3)" "unprognostic (8.43e-2)" "unprognostic (1.07e-1)" "unprognostic (8.64e-2)" "unprognostic (5.80e-2)" 0.6 1.4 1.0 3.9 1.7 2.2 6.2 7.9 4.8 6.3 0.0 1.1 2.2 0.3 1.7 19.3 3.2 2.9 0.2 2.4 1.0 0.8 2.1 1.8 5.3 3.3 3.1 0.1 5.1 0.0 7.9 0.4 3.6 14.6 0.8 44.8 16.4 5.8 0.2 59.6 3.3 0.1 1.2 5.5 2.0 0.6 6.9 4.4 1.7 0.0 6.5 9.1 18.3 7.2 0.3 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.2 0.2 0.0 17.1 0.0 130.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 58.9 0.0 32.8 0.0 0.0 0.0 0.0 3.1 0.3 0.6 0.0 0.0 0.1 1.9 1.4 0.1 0.1 0.0 0.2 6.1 14.7 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 0.6 0.2 1.0 1.7 7.9 4.8 2.4 1.0 3.3 3.1 3.6 1.2 6.9 7.2 0.2 0.0 1.7 2.9 6.1 15.4 14.5 22.8 10.8 102.5 1.7 5.5 3.3 2.8 10.8 0.0 75.0 0.0 7.3 0.7 1.9 0.1 0.1 0.7 0.2 0.7 1.2 0.0 9.3 0.0 0.0 0.4 1.5 1.4 0.0 0.1 0.0 4.9 0.1 26.9 19.8 1.9 2.0 0.3 1.1 0.2 0.0 0.5 3.6 1.9 0.4 14.9 7.2 2.5 37.4 0.5 0.6 0.0 1.9 4.9 3.8 33.5 5.8 169.0 0.0 0.0 1.0 0.2 0.3 13.0 14.6 0.0 7.0 0.1 0.5 9.2 PLCXD1 FLJ11323 ENSG00000182378 "Phosphatidylinositol specific phospholipase C X domain containing 1" Q9NUJ7 X 276322-303356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 34.7;Distal enterocytes: 34.2;Gastric mucus-secreting cells: 33.1;Paneth cells: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A549: 110.4;HEL: 172.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007721 Approved Approved Cytosol NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007721: AB_1079630" "unprognostic (2.73e-2)" "unprognostic (5.67e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.80e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.92e-2)" "unprognostic (1.72e-2)" "unprognostic (4.80e-2)" "unprognostic (7.25e-2)" "unprognostic (1.11e-3)" "prognostic unfavorable (7.82e-14)" "unprognostic (6.01e-2)" "unprognostic (1.95e-1)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" 14.7 4.1 4.6 9.4 8.8 32.9 9.7 13.0 19.2 10.0 0.0 8.2 8.6 5.6 1.4 17.5 9.1 8.8 5.6 4.4 0.0 5.7 10.1 7.4 17.3 3.4 1.5 12.8 7.5 3.2 7.7 7.8 4.4 7.5 5.7 6.0 11.4 3.7 8.4 18.7 12.5 2.7 0.5 17.5 26.9 6.7 4.0 8.9 10.4 2.7 9.0 6.1 9.7 13.4 28.4 110.4 25.7 38.8 5.0 3.9 20.4 24.4 2.9 12.8 12.4 40.6 29.1 34.8 17.9 10.7 19.0 8.5 6.3 15.9 6.7 21.2 46.2 172.6 36.1 59.7 15.6 17.4 63.1 20.1 1.9 47.0 4.9 8.6 9.7 57.2 44.0 18.7 9.2 8.2 52.3 24.2 57.8 7.1 19.2 29.1 13.3 53.9 3.9 12.9 25.9 15.0 24.6 14.4 21.1 17.5 27.6 22.0 7.2 17.1 28.2 18.5 26.9 6.3 17.9 86.4 11.0 44.4 18.2 3.7 2.7 5.4 1.9 6.0 2.7 1.6 1.4 2.4 2.0 5.6 1.8 1.9 3.3 1.2 9.0 2.1 3.2 2.3 4.6 8.8 13.0 19.2 4.4 0.0 3.4 1.5 4.4 0.5 4.0 13.4 15.8 9.6 34.7 5.5 4.1 6.9 13.6 3.9 2.2 7.4 4.7 3.6 6.5 10.0 2.8 0.0 2.1 10.1 4.9 34.2 0.0 6.3 0.9 1.6 3.4 6.1 3.0 9.9 5.3 1.8 11.3 6.1 33.1 3.2 3.8 32.1 4.6 6.9 5.5 8.4 6.1 11.2 0.0 7.3 9.8 0.9 2.5 11.9 0.0 5.6 3.7 2.3 9.2 0.5 5.7 18.8 40.9 3.8 2.7 5.3 3.0 1.7 1.3 7.1 13.1 6.5 7.9 8.4 15.9 4.2 8.7 27.0 3.8 2.8 9.4 8.0 PLCXD3 ENSG00000182836 "Phosphatidylinositol specific phospholipase C X domain containing 3" Q63HM9 5 41306952-41510628 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;heart muscle: 33.2;ovary: 22.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 138.2;Endometrial stromal cells: 58.7;Enteroendocrine cells: 42.4;Inhibitory neurons: 163.5;Microglial cells: 52.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 8.5;PC-3: 7.5;SH-SY5Y: 34.3;TIME: 18.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046849 Uncertain Approved "Golgi apparatus" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA046849: AB_2679838" "unprognostic (1.71e-1)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (7.04e-3)" "unprognostic (1.43e-1)" "unprognostic (2.44e-1)" "unprognostic (4.90e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-2)" "unprognostic (3.12e-1)" "unprognostic (6.38e-3)" "unprognostic (2.57e-1)" "unprognostic (2.73e-2)" "unprognostic (2.15e-3)" "unprognostic (5.91e-5)" "unprognostic (5.11e-2)" "unprognostic (6.75e-2)" 3.9 12.7 4.5 0.5 4.1 0.0 2.4 17.8 4.2 2.9 1.1 0.9 0.5 1.1 0.9 0.6 3.4 2.4 33.2 3.4 9.5 5.9 1.6 1.8 1.6 8.2 10.4 22.5 3.6 0.3 5.3 0.1 16.0 1.0 0.6 0.7 0.4 1.0 0.5 0.7 1.2 1.2 7.7 0.2 5.0 0.4 12.1 0.5 1.5 0.7 0.2 1.4 4.0 6.3 0.0 3.7 0.0 0.0 0.0 0.0 0.0 1.8 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.4 34.3 0.0 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 4.1 17.8 4.2 3.4 9.5 8.2 10.4 16.0 7.7 12.1 6.3 8.7 0.0 0.0 7.5 0.1 0.1 0.1 0.0 0.0 0.7 0.1 0.0 138.2 5.7 0.0 0.0 0.0 0.1 0.0 0.1 3.9 0.3 0.9 1.7 58.7 13.6 42.4 5.3 27.8 0.0 2.0 10.3 0.0 1.1 0.0 33.4 33.2 0.4 0.1 1.7 163.5 2.2 0.0 0.6 0.3 4.4 7.8 0.2 0.0 52.5 0.0 0.4 0.0 7.5 1.3 0.9 0.0 0.4 0.0 0.3 0.1 10.4 0.0 0.2 6.6 0.2 2.9 0.2 0.0 0.2 0.0 0.1 0.3 9.7 0.1 0.1 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 519.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 57.5;SK-MEL-30: 31.1;TIME: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" 7.8 26.4 9.2 6.6 24.7 7.8 7.5 18.4 13.6 10.4 4.5 14.6 46.9 6.2 2.8 33.0 6.4 86.8 24.4 10.5 14.3 12.0 33.7 4.7 9.1 24.8 22.0 24.2 21.2 1.6 2.3 10.7 23.5 3.4 14.7 0.5 13.8 6.0 2.5 29.2 43.9 4.8 14.7 15.7 8.2 5.0 19.0 4.1 3.7 6.8 10.8 5.1 12.4 41.4 4.5 7.2 3.7 1.4 11.2 12.6 7.7 2.3 9.9 3.5 4.3 1.1 6.4 0.0 17.0 0.9 24.0 15.2 0.6 2.0 5.7 3.6 3.2 4.2 11.5 26.1 4.9 7.3 18.9 4.9 10.9 4.2 2.0 10.0 57.5 1.2 2.8 0.0 0.9 1.3 0.0 6.4 0.8 11.9 5.1 0.2 1.5 0.1 8.9 1.8 0.1 0.1 7.9 4.7 31.1 5.1 9.0 9.7 50.7 1.5 5.7 4.0 2.5 9.6 8.2 0.1 6.7 8.6 1.9 8.3 1.8 2.3 0.3 1.1 2.6 0.0 0.2 0.6 0.6 0.0 0.0 0.1 1.0 2.2 0.4 0.0 0.8 0.6 9.2 24.7 18.4 13.6 10.5 14.3 24.8 22.0 23.5 14.7 19.0 41.4 7.7 0.0 4.7 2.0 0.9 7.1 3.4 11.0 10.8 0.4 4.9 5.6 33.6 57.2 11.1 1.8 0.0 3.0 1.9 37.5 3.9 8.4 13.1 1.0 4.8 7.4 4.2 6.3 8.9 3.4 3.7 15.7 27.0 1.3 27.9 10.4 6.4 15.9 20.0 0.0 12.1 23.6 6.1 13.2 2.4 9.5 10.5 10.2 12.4 98.4 5.4 0.0 1.0 12.5 519.6 2.4 18.3 4.5 3.4 0.7 38.3 48.0 9.9 0.1 19.7 3.8 8.4 6.1 5.3 93.5 34.9 2.3 2.3 12.1 17.8 4.7 PLD4 C14orf175 ENSG00000166428 "Phospholipase D family member 4" Q96BZ4 14 104924713-104937761 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.4;brain: 16.7;lymphoid tissue: 11.3" "Cell type enriched" "Detected in many" 7 "dendritic cells: 284.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 3621.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 3621.6" "Group enriched" "Detected in some" 4 "HMC-1: 127.3;RPMI-8226: 85.5;THP-1: 191.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051512 Uncertain NA NA 2900000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA051512: AB_2681515" "unprognostic (4.50e-3)" "unprognostic (1.78e-4)" "unprognostic (7.12e-2)" "unprognostic (5.30e-3)" "unprognostic (5.54e-2)" "unprognostic (2.91e-3)" "unprognostic (2.56e-1)" "unprognostic (4.76e-3)" "unprognostic (1.45e-3)" "unprognostic (1.19e-3)" "unprognostic (3.45e-3)" "unprognostic (3.89e-1)" "unprognostic (6.90e-3)" "unprognostic (8.94e-2)" "unprognostic (2.83e-1)" "unprognostic (1.28e-2)" "unprognostic (2.41e-1)" 0.4 1.0 5.1 5.7 4.7 13.4 1.5 7.0 7.1 1.0 0.4 0.8 3.8 1.0 0.2 0.6 1.8 2.4 0.5 4.5 7.3 0.8 0.5 1.8 11.3 15.7 6.8 0.5 1.1 1.2 2.1 0.8 10.3 1.7 0.5 0.5 3.5 1.8 0.3 0.6 5.1 0.5 13.9 10.4 2.8 0.6 9.4 2.8 0.6 0.0 9.4 1.9 0.4 16.7 0.1 0.2 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 9.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 127.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 10.7 0.1 0.0 0.1 30.0 0.1 85.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 191.5 0.0 0.1 0.3 0.1 0.2 0.4 0.0 0.1 0.2 1.6 0.3 4.6 43.0 699.5 1.0 188.4 1.9 222.7 0.8 1.2 545.8 198.4 1.7 0.4 9.8 25.4 297.9 3621.6 1.0 72.9 5.1 4.7 7.0 7.1 4.5 7.3 15.7 6.8 10.3 13.9 9.4 16.7 0.8 0.0 0.0 0.3 34.7 0.4 0.1 0.0 0.0 2.7 0.6 2.8 1.4 0.0 0.0 0.0 0.0 0.2 284.8 0.0 0.0 0.0 0.7 0.1 0.3 2.7 0.0 5.5 0.1 0.0 0.4 1.1 1.1 0.4 3.8 0.0 0.0 0.0 30.6 1.7 0.1 0.0 0.0 1.3 32.0 4.7 0.0 38.0 5.4 22.5 11.3 0.1 2.1 0.5 0.1 0.0 0.0 0.0 2.3 0.1 0.0 0.1 0.0 1.1 6.6 1.6 0.3 1.6 1.6 0.0 0.4 0.3 2.2 0.0 0.1 0.0 PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 51.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 149.0;Pancreatic endocrine cells: 179.8;Suprabasal keratinocytes: 90.6;Theca cells: 107.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 91.0;CAPAN-2: 94.4;HBEC3-KT: 177.4;PC-3: 64.1;TIME: 69.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles Cytosol "HPA001208: AB_1079631" "unprognostic (4.41e-3)" "unprognostic (3.77e-1)" "unprognostic (1.15e-1)" "unprognostic (6.23e-2)" "unprognostic (6.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.97e-1)" "unprognostic (9.21e-3)" "prognostic unfavorable (8.26e-5)" "unprognostic (1.06e-1)" "unprognostic (3.09e-3)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (8.98e-2)" "unprognostic (4.59e-2)" 0.8 51.1 0.3 5.5 0.3 12.7 3.9 0.8 0.6 3.9 0.1 25.1 29.6 1.5 32.4 16.4 1.7 3.9 0.3 0.4 0.2 9.7 29.7 1.6 0.2 0.3 0.2 0.6 7.9 7.0 1.3 1.5 0.3 7.7 28.7 0.1 6.8 4.2 0.3 26.5 32.6 1.3 0.2 0.6 20.6 3.1 0.4 22.9 23.5 0.2 5.5 12.1 7.9 0.4 91.0 13.4 0.0 0.1 0.0 1.0 8.4 17.9 2.7 4.2 5.2 48.8 94.4 0.0 17.3 2.5 0.2 42.4 0.1 177.4 9.6 0.1 0.7 0.0 19.4 0.4 3.8 0.0 0.0 1.9 12.3 4.6 55.4 0.0 14.8 0.0 0.4 0.4 3.0 28.9 0.0 0.2 0.3 57.4 64.1 0.0 0.1 14.0 30.0 2.4 0.7 0.2 17.0 7.9 5.2 0.9 11.6 0.9 69.3 0.0 54.1 0.3 0.4 0.3 0.2 0.3 10.7 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.4 0.0 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.8 0.6 0.4 0.2 0.3 0.2 0.3 0.2 0.4 0.4 0.1 0.0 1.1 1.0 0.6 149.0 29.0 69.9 37.0 0.0 4.9 6.0 0.5 10.0 11.8 5.5 0.0 1.0 0.0 25.0 3.9 42.1 0.1 2.3 0.2 2.0 8.4 16.0 0.8 46.3 5.5 4.2 37.2 2.2 0.0 24.0 0.0 11.5 6.8 0.0 0.6 68.5 26.4 1.3 57.1 0.3 0.3 7.4 21.4 0.0 5.2 0.0 0.0 0.5 0.3 179.8 23.9 0.0 0.0 15.8 47.9 3.2 4.5 0.0 0.0 0.0 4.6 0.4 2.3 21.2 90.6 1.5 1.3 107.7 54.8 25.5 PLEKHA1 TAPP1 ENSG00000107679 "Pleckstrin homology domain containing A1" Q9HB21 10 122374696-122442602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 10.3;NK-cells: 21.3;T-cells: 27.1" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 203.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002043, HPA064795" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA002043: AB_1079632, HPA064795: AB_2685354" "unprognostic (1.79e-2)" "unprognostic (3.18e-2)" "unprognostic (2.70e-1)" "unprognostic (5.44e-3)" "unprognostic (7.41e-2)" "unprognostic (1.69e-1)" "unprognostic (5.50e-2)" "unprognostic (4.07e-2)" "unprognostic (3.88e-1)" "unprognostic (2.69e-1)" "unprognostic (7.98e-2)" "unprognostic (7.63e-2)" "unprognostic (1.11e-1)" "unprognostic (1.46e-1)" "unprognostic (7.42e-2)" "unprognostic (4.31e-2)" "unprognostic (5.23e-2)" 18.0 10.4 21.2 13.9 25.5 4.4 19.6 10.7 42.0 18.6 5.0 21.4 25.9 25.9 20.5 39.4 12.7 24.0 29.2 25.9 14.8 39.1 38.7 36.6 14.9 12.4 14.9 19.2 27.3 27.6 21.8 37.3 13.3 17.9 20.1 19.8 25.2 18.8 31.8 66.5 25.1 23.6 13.2 13.7 21.2 40.7 13.7 15.6 27.3 57.4 18.0 24.9 21.7 36.9 25.9 23.5 23.3 16.1 33.1 37.5 28.0 28.2 49.1 16.8 18.0 20.0 31.8 16.1 13.3 25.6 17.0 55.4 22.3 86.1 15.4 11.4 21.8 0.0 22.6 23.6 21.8 2.9 7.3 20.5 69.7 13.9 58.3 27.5 56.8 33.2 24.3 0.1 15.6 9.9 14.8 2.5 18.1 39.3 15.5 4.0 33.1 3.2 203.2 28.3 31.6 15.5 36.4 26.8 28.9 32.7 14.9 0.3 54.6 14.1 11.5 15.4 14.3 0.1 0.0 5.4 21.6 0.1 8.8 0.3 2.7 2.3 27.1 2.4 17.5 5.1 16.3 21.9 3.2 10.3 25.4 21.9 0.8 21.3 2.9 1.6 11.9 11.6 21.2 25.5 10.7 42.0 25.9 14.8 12.4 14.9 13.3 13.2 13.7 36.9 48.6 144.2 42.0 19.9 28.0 72.8 54.7 51.6 97.9 46.5 25.6 19.2 55.9 55.8 46.0 57.0 75.0 58.4 47.6 39.1 41.1 63.1 202.0 50.2 30.6 70.8 22.3 6.9 133.8 85.3 53.9 34.3 28.1 83.7 5.1 20.8 32.5 45.1 37.2 26.9 92.9 19.6 22.4 23.7 23.6 336.5 44.1 20.4 24.9 35.6 28.5 20.2 147.2 35.2 161.9 71.4 26.9 36.1 7.4 91.4 64.4 118.1 29.1 49.5 26.3 32.2 28.9 119.4 86.1 71.6 84.8 39.7 39.7 14.7 27.5 83.5 PLEKHA6 "KIAA0969, PEPP3" ENSG00000143850 "Pleckstrin homology domain containing A6" Q9Y2H5 1 204218853-204377665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 111.0;Distal enterocytes: 66.6;Excitatory neurons: 102.6;Inhibitory neurons: 62.5;Oligodendrocyte precursor cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 60.3;BEWO: 94.6;CAPAN-2: 79.2;OE19: 80.9;RT4: 66.4;SK-BR-3: 58.4;T-47d: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028152, HPA028157, HPA054311" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Vesicles "HPA028152: AB_10601048, HPA028157: , HPA054311: AB_2682446" "unprognostic (9.81e-3)" "unprognostic (3.05e-1)" "unprognostic (1.59e-2)" "unprognostic (3.14e-2)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (2.37e-2)" "unprognostic (1.38e-2)" "unprognostic (9.01e-2)" "unprognostic (3.32e-1)" "unprognostic (9.60e-3)" "unprognostic (1.53e-1)" "unprognostic (5.02e-3)" "unprognostic (1.23e-1)" "unprognostic (8.22e-2)" "unprognostic (5.17e-2)" "prognostic favorable (3.57e-4)" 5.1 6.6 20.4 6.0 21.6 0.4 13.7 20.9 34.4 4.1 9.1 32.2 25.5 4.8 12.9 17.2 9.3 13.2 20.8 19.6 18.7 27.4 27.5 3.2 0.6 23.1 24.3 4.6 10.2 5.7 31.1 8.8 23.3 13.8 29.3 11.4 9.0 13.9 6.0 4.0 29.5 3.8 17.9 3.1 39.7 5.4 34.6 1.0 4.0 2.4 2.4 12.7 7.5 24.1 60.3 36.8 23.7 0.1 0.3 0.6 94.6 2.1 6.6 0.2 0.3 17.8 79.2 0.3 17.3 1.4 0.3 6.7 0.3 6.5 0.3 0.2 3.8 0.2 15.2 25.7 3.5 0.0 0.1 1.0 19.6 0.0 5.0 7.2 10.4 0.8 0.1 0.2 23.9 26.7 0.1 0.1 7.4 80.9 44.6 0.0 0.2 0.1 23.0 66.4 4.8 48.4 26.6 58.4 0.4 4.9 55.3 0.3 0.7 0.0 1.0 0.3 0.5 0.2 0.0 0.1 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 21.6 20.9 34.4 19.6 18.7 23.1 24.3 23.3 17.9 34.6 24.1 0.2 0.0 10.9 111.0 0.3 0.1 4.2 1.9 0.6 41.6 15.7 8.1 16.6 37.1 4.5 9.2 20.9 6.6 0.5 66.6 3.9 8.4 10.4 4.0 1.3 1.2 16.8 2.7 102.6 5.1 2.4 9.0 40.8 6.2 0.0 0.3 5.0 21.4 0.8 18.5 62.5 32.7 4.1 0.6 0.7 4.0 5.3 0.7 0.0 15.0 0.1 1.2 0.0 85.5 41.8 13.3 33.2 3.8 0.1 6.9 15.2 11.7 7.2 7.1 0.0 26.4 1.1 0.6 0.2 1.4 0.6 21.6 0.6 0.1 34.5 13.7 PLEKHB1 "KPL1, PHR1, PHRET1" ENSG00000021300 "Pleckstrin homology domain containing B1" Q9UF11 11 73646178-73662819 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 1531.3;choroid plexus: 728.4;retina: 758.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 344.0;Early spermatids: 145.6;Late spermatids: 184.4;Muller glia cells: 496.6;Rod photoreceptor cells: 460.4" "Cancer enhanced" "Detected in all" "glioma: 59.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 83.7" "Lineage enriched" "Detected in many" 5 "T-cells: 83.7" "Cell line enhanced" "Detected in many" "Hep G2: 77.2;OE19: 53.3;U-266/84: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.20e-1)" "unprognostic (5.07e-1)" "unprognostic (2.91e-1)" "unprognostic (9.72e-2)" "unprognostic (2.16e-1)" "unprognostic (1.48e-1)" "unprognostic (2.46e-2)" "unprognostic (1.41e-3)" "unprognostic (3.01e-1)" "unprognostic (3.94e-2)" "prognostic favorable (6.02e-4)" "unprognostic (3.59e-1)" "prognostic favorable (1.99e-6)" "unprognostic (2.64e-1)" "unprognostic (7.23e-2)" "unprognostic (4.47e-1)" "unprognostic (7.44e-2)" 2.7 6.7 1011.3 7.7 1362.5 1.3 10.4 1275.8 1156.9 6.9 728.4 52.9 11.6 3.0 15.0 4.7 24.3 10.3 14.7 914.2 1059.3 12.3 2.1 15.2 8.9 1472.5 1259.8 3.0 22.9 88.1 135.2 0.9 1433.2 13.2 9.0 758.1 59.0 8.6 9.4 5.2 19.8 3.0 1263.6 4.2 20.5 20.2 1172.4 5.6 28.8 11.9 7.6 8.2 5.5 1531.3 0.7 2.0 4.8 3.8 2.0 0.6 0.2 0.2 0.1 0.3 0.3 8.5 16.2 0.1 20.0 0.5 0.6 0.4 2.6 0.4 0.4 11.0 12.5 0.0 1.0 77.2 1.2 0.0 0.2 0.7 0.0 0.3 0.0 4.1 0.1 19.4 0.3 10.5 0.3 6.3 5.3 0.3 3.1 53.3 1.0 3.8 0.1 2.6 0.7 1.4 11.8 2.8 0.0 0.3 1.7 3.5 5.6 1.0 0.0 0.0 2.2 0.1 1.6 17.5 30.4 11.3 2.8 0.0 0.8 0.2 0.5 1.1 17.1 0.0 41.5 18.3 41.4 30.6 0.5 7.9 83.7 47.3 0.9 4.3 0.1 0.9 26.9 27.4 1011.3 1362.5 1275.8 1156.9 914.2 1059.3 1472.5 1259.8 1433.2 1263.6 1172.4 1531.3 0.7 6.4 13.5 25.5 5.3 0.4 1.1 1.7 0.6 53.6 19.1 11.8 8.1 25.8 4.5 7.3 344.0 0.5 1.9 0.8 11.7 30.6 145.6 27.4 0.5 3.9 62.8 0.0 1.1 0.8 0.1 2.0 13.7 3.7 11.4 10.4 1.8 0.2 2.7 20.2 0.6 11.2 22.4 0.3 0.3 184.4 2.5 0.9 10.6 7.5 1.6 496.6 6.2 15.6 96.4 2.9 3.9 0.7 1.0 4.0 0.9 13.9 42.8 460.4 0.0 2.5 1.8 2.6 1.7 0.3 0.1 0.1 9.7 0.1 6.5 1.6 PLEKHD1 UPF0639 ENSG00000175985 "Pleckstrin homology and coiled-coil domain containing D1" A6NEE1 14 69484692-69531551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;parathyroid gland: 6.0;retina: 8.8" "Group enriched" "Detected in some" 13 "Bipolar cells: 60.9;Horizontal cells: 230.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 3.7" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.7" "Cell line enhanced" "Detected in some" "OE19: 1.1;SK-BR-3: 2.4;T-47d: 2.3;U-266/70: 1.0" "Region enhanced" "Detected in many" "cerebellum: 30.0" "Low region specificity" "Detected in many" HPA051875 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "HPA051875: AB_2681648" "unprognostic (8.73e-2)" "unprognostic (4.64e-3)" "unprognostic (3.73e-2)" "unprognostic (4.03e-2)" "unprognostic (7.58e-2)" "unprognostic (3.15e-3)" "unprognostic (1.44e-1)" "unprognostic (1.64e-3)" "unprognostic (3.28e-1)" "unprognostic (1.83e-1)" "unprognostic (4.56e-3)" "unprognostic (1.22e-1)" "unprognostic (5.49e-2)" "unprognostic (8.08e-2)" "unprognostic (2.28e-1)" "unprognostic (2.74e-2)" "unprognostic (1.42e-2)" 0.1 0.2 1.2 0.1 0.5 0.5 0.6 8.1 2.4 0.3 0.0 0.0 0.2 0.1 1.6 0.1 0.1 0.1 0.1 0.3 1.4 1.4 0.0 0.2 0.9 1.4 3.2 0.1 0.2 6.0 0.3 0.1 1.6 0.1 0.0 8.8 1.6 0.3 0.1 1.5 0.1 0.0 0.4 0.2 0.2 1.2 4.5 0.1 2.2 0.0 0.2 0.0 0.0 1.1 0.1 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.4 0.1 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.2 0.2 0.3 0.7 0.0 2.4 0.0 0.0 2.3 0.0 0.0 0.1 0.3 0.1 0.1 1.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.7 0.0 0.0 1.2 0.5 8.1 2.4 0.3 1.4 1.4 3.2 1.6 0.4 4.5 1.1 0.5 0.0 7.3 0.3 0.0 0.4 1.8 0.1 0.0 60.9 0.6 0.4 1.3 0.0 2.0 0.0 4.2 0.1 11.2 0.1 3.9 0.1 0.5 0.4 0.2 1.0 0.0 0.0 6.3 0.2 0.1 0.6 0.0 0.6 1.3 0.1 0.4 0.0 0.1 230.5 3.3 0.0 0.0 0.0 0.6 0.1 0.0 1.0 0.0 0.0 0.6 1.7 1.0 0.0 0.1 0.3 0.0 0.0 0.0 1.4 0.2 0.5 0.9 5.9 0.0 1.4 0.6 0.8 0.3 0.0 0.3 0.1 2.3 0.2 0.1 0.7 PLEKHF1 "APPD, MGC4090, PHAFIN1, ZFYVE15" ENSG00000166289 "Pleckstrin homology and FYVE domain containing 1" Q96S99 19 29665459-29675477 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 77.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 59.2;Leydig cells: 78.3;NK-cells: 166.9;Peritubular cells: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 13 "NK-cells: 82.3;T-cells: 183.9" "Cell line enhanced" "Detected in many" "BEWO: 39.0;SK-BR-3: 32.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA025925 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA025925: AB_1844958" "unprognostic (5.01e-2)" "unprognostic (6.39e-2)" "unprognostic (1.31e-2)" "unprognostic (3.04e-2)" "unprognostic (9.43e-3)" "unprognostic (2.57e-1)" "unprognostic (4.73e-2)" "unprognostic (1.93e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-3)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.54e-5)" "unprognostic (1.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-2)" "prognostic favorable (4.54e-4)" 18.0 3.6 9.4 4.6 12.4 6.7 17.0 10.8 9.7 18.1 5.9 9.9 4.0 18.8 1.9 15.3 15.5 4.6 24.8 7.8 10.1 4.9 16.4 10.5 9.0 14.2 12.5 8.4 4.9 5.9 2.5 4.9 11.3 16.5 1.1 0.2 18.6 6.1 77.3 8.5 10.0 2.7 10.8 14.4 7.2 3.4 13.9 7.4 6.3 38.5 5.1 16.9 14.9 14.0 14.3 5.2 0.1 3.3 10.5 9.0 39.0 3.6 4.9 4.4 7.1 3.3 6.4 0.1 12.7 4.7 8.1 12.6 1.1 3.3 0.7 9.7 7.1 7.1 2.6 6.5 17.9 0.4 19.0 15.8 1.3 4.7 8.7 2.8 3.8 7.1 8.2 0.0 2.5 1.9 1.0 5.9 0.7 2.3 2.5 0.1 4.7 4.0 3.0 22.5 0.1 2.3 2.0 32.9 18.4 3.2 12.0 2.1 3.5 5.7 5.9 7.2 6.7 2.5 27.3 1.2 6.3 7.5 2.0 10.4 0.8 0.2 183.9 0.5 128.1 5.5 74.0 147.2 1.4 10.2 43.9 82.4 2.1 82.3 0.9 0.6 76.4 67.1 9.4 12.4 10.8 9.7 7.8 10.1 14.2 12.5 11.3 10.8 13.9 14.0 5.2 0.0 0.5 1.3 9.5 55.2 29.0 15.8 17.1 0.8 12.7 9.0 8.7 18.6 9.6 9.2 0.0 59.2 53.6 0.9 5.9 22.1 0.5 4.4 10.1 11.2 0.0 2.7 0.2 8.3 7.4 17.6 2.0 7.8 0.0 0.8 12.5 10.0 11.1 0.0 0.4 1.2 16.2 3.0 12.6 1.9 78.3 3.0 17.8 9.4 0.5 5.5 166.9 0.0 5.6 3.8 2.5 72.6 10.1 34.0 0.5 6.0 4.2 0.5 0.0 24.7 7.6 0.4 1.8 8.9 35.8 38.4 40.9 0.9 1.2 25.4 PLEKHF2 "FLJ13187, PHAFIN2, ZFYVE18" ENSG00000175895 "Pleckstrin homology and FYVE domain containing 2" Q9H8W4 8 95133785-95156685 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 102.6;U-698: 109.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024829 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA024829: AB_10603127" "unprognostic (4.08e-2)" "unprognostic (2.98e-2)" "unprognostic (5.72e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.67e-2)" "unprognostic (4.83e-2)" "unprognostic (1.19e-1)" "unprognostic (2.67e-1)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (5.94e-2)" "prognostic favorable (1.49e-4)" "unprognostic (2.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (4.61e-3)" 12.4 6.1 5.5 21.3 5.5 84.8 21.6 6.1 6.7 9.2 6.9 16.0 12.6 7.4 14.6 15.4 8.9 11.2 8.9 5.2 5.7 22.2 14.7 17.5 53.1 6.3 5.8 7.3 11.8 6.9 3.6 15.1 6.2 9.3 13.9 14.8 11.8 7.4 10.7 19.5 13.7 7.1 6.6 22.6 21.9 12.3 5.4 23.8 9.7 9.3 56.1 12.7 7.5 8.3 27.5 4.5 7.0 4.2 10.0 11.1 37.6 14.9 20.0 12.7 13.6 11.3 29.7 102.6 12.6 10.5 6.6 33.1 10.9 18.1 18.3 19.2 7.4 49.4 10.0 8.8 9.9 9.9 68.7 7.1 25.0 10.0 18.8 14.9 14.1 32.9 32.6 13.0 13.6 16.8 29.0 12.8 4.2 50.1 20.6 11.5 7.1 14.0 10.4 24.2 9.3 5.4 11.3 13.5 27.8 9.7 36.2 16.0 9.0 9.8 6.7 8.6 8.7 17.2 14.9 109.4 7.5 22.8 14.1 107.2 21.6 43.0 9.0 18.6 10.8 69.7 11.2 13.9 24.3 78.6 12.9 12.7 29.8 12.4 16.0 10.1 13.7 19.4 5.5 5.5 6.1 6.7 5.2 5.7 6.3 5.8 6.2 6.6 5.4 8.3 29.3 12.8 14.1 7.2 88.8 61.4 73.4 29.7 56.3 17.0 49.0 22.7 7.0 31.5 26.1 5.5 14.6 51.6 17.8 46.7 29.4 13.6 59.5 47.1 12.0 18.5 33.6 34.5 5.0 22.0 36.1 11.9 31.1 59.5 60.4 14.4 25.0 11.0 29.6 6.7 2.4 14.6 57.0 22.6 54.0 19.8 8.7 34.7 21.4 14.0 31.9 19.1 13.4 10.6 4.7 14.6 39.0 3.8 21.3 42.4 20.7 95.9 26.2 31.7 13.1 10.8 14.5 55.2 16.0 47.2 57.7 50.9 27.4 6.0 17.7 75.4 PLEKHG5 "GEF720, KIAA0720, Syx, Tech" ENSG00000171680 "Pleckstrin homology and RhoGEF domain containing G5" O94827 1 6467122-6520074 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.4;skin 1: 102.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 57.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 32.1;TIME: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049570 Uncertain Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA049570: AB_2680818" "unprognostic (5.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.47e-1)" "unprognostic (2.81e-1)" "unprognostic (1.50e-3)" "unprognostic (5.10e-2)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.02e-2)" "unprognostic (4.85e-1)" "unprognostic (2.70e-2)" "unprognostic (1.28e-3)" "unprognostic (4.85e-1)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (4.85e-2)" 18.7 15.0 4.4 2.9 2.6 0.6 12.0 57.4 16.6 14.0 0.0 7.3 6.4 7.5 1.9 21.6 8.6 7.3 16.4 13.0 0.0 6.5 1.8 6.0 5.0 0.0 0.0 7.5 5.1 4.4 43.3 12.4 1.8 9.9 3.5 3.4 9.3 7.2 6.8 102.5 8.4 3.9 0.0 50.9 4.4 5.4 0.0 2.0 7.2 3.0 3.3 5.9 14.3 0.0 7.1 2.7 11.9 9.4 1.5 4.2 3.1 8.4 7.0 3.2 2.1 6.9 18.8 0.3 22.6 2.8 4.9 22.6 2.2 23.7 1.3 16.5 3.0 0.0 15.1 2.9 1.9 0.0 1.3 5.5 10.2 8.1 12.5 17.4 24.9 1.7 0.0 1.5 0.6 5.0 0.5 32.1 4.9 2.3 23.8 0.1 2.7 2.3 6.3 3.1 10.5 25.2 1.1 8.2 1.5 5.3 8.2 0.5 30.3 8.1 5.0 0.0 6.6 0.1 0.0 2.4 9.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.6 57.4 16.6 13.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 10.6 0.0 1.5 1.0 0.2 7.4 2.3 4.7 8.0 1.4 1.4 2.2 4.1 1.5 3.6 3.7 2.1 2.6 0.1 4.2 0.0 1.3 8.6 2.5 5.9 9.8 3.5 0.4 17.4 1.3 4.0 1.9 3.1 3.2 0.0 4.0 7.5 0.3 5.3 1.7 9.6 6.4 6.1 0.8 1.3 5.7 1.8 2.4 0.0 7.5 0.0 9.7 0.0 2.0 1.2 5.1 5.6 8.6 0.4 3.8 4.1 0.4 2.7 1.5 13.1 2.1 1.7 2.1 5.1 10.8 14.5 1.9 0.7 2.5 2.8 5.8 PLEKHM1 KIAA0356 ENSG00000225190 "Pleckstrin homology and RUN domain containing M1" Q9Y4G2 17 45435900-45490749 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.5" "Cell line enhanced" "Detected in many" "OE19: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025018, HPA039473" Approved Supported Nucleoli,Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoli "HPA025018: AB_1855465, HPA039473: AB_2676526" "unprognostic (1.52e-1)" "unprognostic (3.13e-2)" "unprognostic (4.29e-2)" "prognostic favorable (1.28e-6)" "unprognostic (8.71e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.20e-2)" "unprognostic (1.88e-1)" "unprognostic (2.93e-2)" "unprognostic (4.02e-1)" "unprognostic (3.93e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" 7.0 6.4 2.9 5.5 2.9 9.7 6.2 3.5 3.8 12.9 3.2 6.5 3.5 5.7 1.0 31.7 5.9 5.3 6.2 2.8 3.1 3.6 3.6 8.8 4.8 3.7 3.1 4.9 6.1 4.4 5.7 2.9 3.2 5.1 3.6 1.6 14.4 0.9 12.3 11.8 6.2 2.0 2.8 6.8 5.6 3.4 3.4 5.4 6.5 7.2 4.8 6.8 13.6 3.7 7.3 11.0 1.7 5.4 8.4 4.8 0.1 3.3 4.9 1.9 2.6 4.2 6.0 5.2 3.4 3.9 14.1 1.7 4.1 1.9 1.6 13.7 3.5 0.0 5.6 6.9 2.0 0.0 4.3 2.2 4.9 0.9 8.0 3.8 10.0 0.0 5.2 6.2 9.1 6.0 5.2 1.1 1.7 26.6 9.0 2.8 5.6 5.3 6.0 16.8 3.2 2.1 3.2 4.5 5.2 4.8 10.1 5.3 19.1 12.7 3.6 5.2 5.9 0.6 6.2 1.8 7.7 2.8 5.8 2.8 1.2 1.0 0.2 0.3 0.0 1.2 0.6 0.2 0.3 0.3 0.2 0.0 6.5 0.7 0.4 0.2 0.5 0.2 2.9 2.9 3.5 3.8 2.8 3.1 3.7 3.1 3.2 2.8 3.4 3.7 12.6 12.8 18.1 7.8 17.5 18.0 18.1 10.3 6.8 10.4 11.7 8.4 8.7 15.7 12.7 12.9 16.7 4.8 24.3 25.6 5.9 8.1 4.3 24.9 11.1 12.1 13.8 10.8 13.5 8.2 4.7 12.1 19.9 27.9 1.3 5.4 12.8 8.1 9.1 16.8 13.3 13.0 4.1 27.9 15.2 2.0 7.2 21.1 7.2 9.4 13.7 7.3 14.4 7.5 20.8 18.3 17.7 7.9 22.9 27.2 8.6 10.5 11.9 8.2 0.0 17.7 7.6 7.6 3.7 10.0 16.3 8.6 18.5 9.3 12.2 43.1 PLEKHN1 DKFZP434H2010 ENSG00000187583 "Pleckstrin homology domain containing N1" Q494U1 1 966482-975865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.9;skin 1: 46.0;vagina: 24.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 29.6;Pancreatic endocrine cells: 38.5;Prostatic glandular cells: 37.9;Squamous epithelial cells: 19.2;Urothelial cells: 52.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 15.1;HaCaT: 26.0;SK-BR-3: 16.6" "Not detected" "Not detected" HPA031742 Uncertain Approved "Nuclear speckles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "HPA031742: AB_10670704" "unprognostic (2.72e-3)" "unprognostic (8.05e-3)" "unprognostic (9.03e-2)" "unprognostic (4.47e-2)" "unprognostic (7.50e-4)" "unprognostic (2.93e-2)" "unprognostic (1.38e-2)" "unprognostic (1.78e-1)" "unprognostic (3.24e-1)" "unprognostic (1.01e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (9.98e-2)" "unprognostic (1.96e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" 0.4 1.6 0.0 0.7 0.1 0.4 1.7 0.0 0.1 11.5 0.0 0.6 0.9 0.4 0.3 54.9 0.9 0.7 0.2 0.0 0.0 2.1 0.9 1.1 0.3 0.0 0.0 0.1 1.1 0.5 0.3 0.4 0.0 3.6 0.1 0.0 10.2 1.2 2.1 46.0 0.8 0.1 0.0 1.2 2.0 0.4 0.1 0.1 0.7 0.0 1.6 7.5 24.2 0.0 15.1 1.4 0.0 1.0 0.1 0.7 2.5 6.8 1.7 4.1 1.1 2.0 11.3 0.0 3.2 3.0 5.7 26.0 0.2 4.5 0.7 5.0 1.0 0.0 5.6 3.3 0.6 0.3 0.2 0.2 3.8 2.9 1.6 3.7 0.5 0.0 0.3 4.0 0.2 8.3 0.0 0.3 0.5 2.4 11.0 0.1 0.0 5.6 4.3 4.2 0.1 0.1 7.5 16.6 1.0 0.4 3.2 0.0 3.2 5.3 2.3 0.5 4.6 3.2 0.1 0.1 6.8 2.5 3.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.2 1.1 0.0 1.9 4.6 29.6 5.0 1.8 0.5 3.8 1.8 0.9 0.0 6.4 0.0 0.0 7.1 1.0 1.9 0.0 13.8 0.0 3.0 1.1 0.7 0.0 0.0 0.0 14.0 2.0 0.9 3.1 8.2 0.0 0.0 0.7 0.3 1.1 3.3 0.0 0.0 8.2 0.3 1.4 0.0 0.0 0.9 1.8 0.0 1.9 0.2 0.0 0.0 0.0 38.5 3.3 0.0 2.5 37.9 0.0 0.1 5.2 0.2 0.0 0.2 1.0 0.0 0.7 19.2 17.3 9.9 2.8 0.0 0.1 52.9 PLEKHS1 "bA211N11.2, C10orf81, FLJ23537" ENSG00000148735 "Pleckstrin homology domain containing S1" Q5SXH7 10 113751262-113783429 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 30.5;cervix: 63.6;intestine: 43.9;pancreas: 36.9;salivary gland: 57.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 35.1;Club cells: 70.7;Endometrial ciliated cells: 33.8;Exocrine glandular cells: 31.1;Ionocytes: 38.7;Proximal enterocytes: 42.1;Respiratory ciliated cells: 157.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 10.1;OE19: 53.5;RT4: 22.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA037583 Approved Vesicles,Centrosome NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Centrosome Vesicles "HPA037583: AB_10671762" "unprognostic (2.64e-1)" "unprognostic (1.64e-2)" "unprognostic (2.74e-2)" "unprognostic (3.60e-2)" "unprognostic (1.07e-1)" "unprognostic (2.63e-2)" "unprognostic (1.74e-2)" "unprognostic (2.36e-2)" "unprognostic (8.43e-2)" "unprognostic (6.82e-2)" "unprognostic (2.57e-1)" "unprognostic (1.21e-2)" "unprognostic (0.00e+0)" "unprognostic (4.00e-3)" "unprognostic (2.19e-1)" "unprognostic (2.27e-1)" "prognostic favorable (1.03e-4)" 0.3 0.1 0.0 7.3 0.0 0.3 30.5 0.0 0.3 63.6 0.0 3.6 43.9 1.8 3.9 1.0 9.4 2.7 0.4 0.0 0.0 0.9 0.1 6.7 0.2 0.2 0.0 0.1 36.9 0.1 0.2 0.1 0.0 6.0 4.7 0.4 57.0 3.3 0.0 0.8 38.7 0.5 0.0 0.2 8.8 0.9 0.0 0.1 0.1 0.0 2.8 1.5 0.0 0.1 0.2 1.4 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.1 0.7 0.2 10.1 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.0 53.5 0.0 0.2 6.4 0.3 1.7 22.3 0.1 0.2 0.1 1.4 0.0 0.0 6.3 0.0 0.0 0.2 0.2 0.2 0.5 4.7 0.2 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 3.2 3.2 0.3 0.0 0.1 0.3 35.1 0.0 0.0 16.6 8.3 0.4 0.0 70.7 0.0 0.0 0.0 0.1 6.7 0.0 4.9 13.2 33.8 0.3 0.5 0.0 0.0 0.2 31.1 0.0 0.6 3.1 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 5.6 38.7 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 1.2 2.8 0.4 0.0 1.4 42.1 0.3 157.3 0.0 0.0 0.3 3.7 0.2 0.1 0.6 0.0 0.0 0.3 0.0 12.1 0.5 PLIN1 PLIN ENSG00000166819 "Perilipin 1" O60240 15 89664367-89679427 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 17 "adipose tissue: 956.3;breast: 463.0" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 59.0" "Group enriched" "Detected in many" 5 "breast cancer: 8.4;liver cancer: 2.3;pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 171 "ASC diff: 208.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024299, CAB033821, CAB037333" Enhanced Uncertain Peroxisomes NA NA 22000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Peroxisomes "CAB033821: AB_2252681, CAB037333: , HPA024299: AB_1855467" "unprognostic (4.62e-2)" "unprognostic (2.22e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-1)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (9.89e-3)" "unprognostic (3.54e-1)" "unprognostic (7.01e-2)" "unprognostic (2.13e-2)" "unprognostic (8.00e-3)" "unprognostic (2.28e-3)" "unprognostic (2.62e-6)" "unprognostic (5.56e-2)" "unprognostic (1.22e-1)" "unprognostic (1.63e-1)" "unprognostic (4.85e-2)" 956.3 11.3 12.0 3.5 14.8 0.3 463.0 7.4 10.6 1.4 5.3 9.3 0.5 0.7 0.4 1.3 1.4 6.6 10.4 10.0 10.3 2.7 40.8 0.7 1.7 6.9 11.5 2.1 6.1 0.2 1.3 0.2 7.8 2.6 3.7 0.6 20.8 0.6 9.5 16.0 13.9 1.5 6.6 1.0 5.5 13.2 10.6 2.3 5.3 17.3 0.1 7.9 3.1 8.2 0.0 0.2 0.2 0.0 208.2 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.7 0.5 0.1 0.7 0.2 0.0 0.2 0.6 0.7 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.1 0.3 0.2 0.1 0.3 1.2 0.1 0.5 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.4 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 14.8 7.4 10.6 10.0 10.3 6.9 11.5 7.8 6.6 10.6 8.2 2.6 0.0 0.0 4.2 0.2 0.1 0.3 0.1 0.0 0.3 0.7 3.0 1.1 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 7.5 0.1 0.2 0.2 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.2 0.0 0.1 1.1 59.0 0.0 0.0 0.3 0.3 0.0 1.0 0.3 7.5 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.2 1.3 0.0 0.0 0.6 0.3 0.1 0.1 0.1 0.0 1.3 1.3 4.8 0.2 0.0 0.4 0.0 0.1 0.1 0.5 0.9 PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502180-4518465 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 764.9;breast: 316.5;skeletal muscle: 249.9" "Cell type enhanced" "Detected in some" "Adipocytes: 12.3;Astrocytes: 12.1;Cardiomyocytes: 35.9;Hepatocytes: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "ASC diff: 249.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 55000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: AB_2679044, HPA054657: AB_2682559" "unprognostic (2.97e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (8.31e-4)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.65e-2)" "unprognostic (6.77e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (9.89e-3)" "unprognostic (1.05e-1)" "unprognostic (2.95e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (6.09e-3)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.94e-3)" 764.9 3.9 8.5 6.4 9.4 2.7 316.5 8.0 5.1 8.8 2.5 70.7 2.3 28.7 2.0 9.6 18.5 8.5 112.8 5.0 6.7 7.6 87.1 3.4 0.8 9.8 9.7 21.8 24.7 0.1 4.4 0.1 7.3 13.4 3.9 0.2 22.6 15.1 249.9 16.3 18.9 20.4 8.5 4.9 25.1 2.7 11.1 0.9 4.1 163.4 0.2 34.3 7.2 7.1 0.1 0.4 0.1 0.7 249.6 1.6 8.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.4 0.0 1.2 0.1 0.0 1.8 0.0 0.6 0.3 0.0 0.1 1.4 3.6 0.1 0.1 8.1 4.7 0.0 0.4 0.1 0.0 0.0 0.2 0.5 0.0 0.5 0.0 0.2 0.3 0.1 5.7 0.3 0.0 0.2 0.0 29.7 0.1 0.4 0.3 0.0 0.0 0.1 1.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 9.4 8.0 5.1 5.0 6.7 9.8 9.7 7.3 8.5 11.1 7.1 12.3 0.0 7.2 12.1 0.2 0.3 1.2 0.4 0.6 0.3 0.9 3.9 35.9 7.2 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.3 1.6 0.4 1.0 0.0 0.0 0.3 1.5 0.3 1.7 3.6 0.6 0.0 1.0 7.5 30.6 0.1 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.6 0.0 0.5 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.9 0.9 0.0 6.6 5.9 1.8 0.5 0.4 0.3 0.3 0.4 0.1 0.3 0.3 1.9 PLIN5 "LSDA5, LSDP5, MLDP, OXPAT" ENSG00000214456 "Perilipin 5" Q00G26 19 4522531-4535224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 202.0;skeletal muscle: 149.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 47.1;Astrocytes: 53.8;Cardiomyocytes: 39.8;Hepatic stellate cells: 42.1;Hepatocytes: 140.5" "Cancer enhanced" "Detected in many" "liver cancer: 9.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.9" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.9" "Cell line enhanced" "Detected in some" "AN3-CA: 2.3;BEWO: 3.2;RT4: 3.1;SH-SY5Y: 2.8;T-47d: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA077050 Supported "Vesicles,Lipid droplets" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Lipid droplets" "HPA077050: " "prognostic favorable (7.68e-4)" "unprognostic (1.01e-1)" "unprognostic (4.22e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (1.24e-2)" "unprognostic (6.06e-3)" "prognostic favorable (2.81e-4)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.63e-1)" "unprognostic (1.54e-1)" "prognostic favorable (1.97e-4)" "unprognostic (3.18e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "prognostic favorable (2.16e-4)" 41.9 6.4 10.8 3.5 11.2 5.2 29.3 6.9 9.6 7.5 12.8 5.4 1.5 2.7 3.9 3.4 12.6 2.0 62.7 8.5 8.1 30.1 202.0 9.3 0.5 8.4 9.2 90.8 112.2 1.5 18.9 0.2 6.9 17.6 0.6 0.9 61.0 3.9 149.2 8.0 5.3 0.5 6.8 8.2 58.9 3.3 9.4 0.4 9.8 24.7 1.0 11.2 2.7 6.4 0.2 0.1 0.5 2.3 1.7 0.1 3.2 0.1 0.1 0.1 0.0 0.2 0.5 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.8 1.1 0.4 0.3 0.4 0.4 0.0 0.0 0.0 0.2 0.2 0.1 0.7 0.2 0.1 0.6 0.1 0.4 0.4 0.3 0.3 0.1 0.1 2.1 0.2 3.1 0.3 2.8 0.2 0.4 0.0 0.2 6.3 0.4 0.3 0.3 0.3 0.2 0.2 0.3 0.1 0.1 0.2 0.6 0.1 1.9 0.4 0.8 0.3 0.3 0.2 0.3 0.2 0.2 0.1 0.4 0.3 0.3 13.9 0.6 0.3 0.3 0.1 0.1 10.8 11.2 6.9 9.6 8.5 8.1 8.4 9.2 6.9 6.8 9.4 6.4 6.0 9.6 47.1 53.8 1.6 0.5 18.4 2.3 4.0 1.2 9.2 1.9 39.8 35.8 11.5 1.8 0.0 0.4 0.1 11.9 9.8 8.7 1.5 20.8 1.4 7.4 0.0 2.7 1.1 12.3 0.5 1.3 16.3 5.1 3.8 18.7 42.1 140.5 0.5 0.0 1.8 6.9 4.1 6.9 0.5 0.3 0.3 2.5 0.0 5.6 0.1 8.1 0.0 11.1 2.0 4.8 1.3 2.6 0.5 6.6 0.5 11.1 10.4 1.2 13.1 25.8 1.8 6.2 6.6 0.5 1.0 1.4 1.1 20.5 8.8 11.5 PLK1 PLK ENSG00000166851 "Polo like kinase 1" P53350 16 23677656-23690367 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.0;lymphoid tissue: 43.9;testis: 33.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.3;Early spermatids: 123.7;Erythroid cells: 38.3;Extravillous trophoblasts: 55.9;Spermatocytes: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 5.6" "Lineage enriched" "Detected in many" 5 "T-cells: 5.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051638, HPA053229" Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA051638: AB_2681561, HPA053229: AB_2682084" "unprognostic (7.21e-3)" "unprognostic (1.77e-1)" "unprognostic (1.98e-3)" "unprognostic (4.97e-3)" "unprognostic (9.56e-2)" "unprognostic (5.12e-2)" "prognostic unfavorable (2.70e-7)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.55e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.33e-1)" "unprognostic (8.10e-2)" "unprognostic (1.19e-1)" "unprognostic (1.26e-2)" 1.4 1.5 2.3 13.4 2.3 32.0 1.5 2.5 3.2 2.3 2.0 9.6 10.4 1.2 0.4 13.9 1.0 1.4 1.0 2.3 2.1 1.4 1.9 1.9 27.8 2.3 2.3 1.3 1.1 0.2 1.2 6.4 2.2 1.2 10.1 1.2 2.4 0.3 1.0 5.7 9.2 4.0 2.0 9.1 6.2 33.1 2.5 43.9 0.9 0.4 30.0 2.8 4.0 2.8 199.9 207.5 166.2 90.9 5.2 11.7 92.8 111.0 74.5 172.5 127.0 184.3 131.0 99.1 56.3 76.5 90.1 112.8 229.5 93.5 206.1 139.5 128.0 125.2 163.4 257.1 1.7 147.5 133.7 4.8 5.2 124.7 125.2 21.6 127.9 127.5 200.7 133.9 134.8 187.8 139.8 151.4 189.5 82.1 103.5 217.2 111.7 160.0 49.3 43.9 94.3 65.3 126.8 88.9 55.8 94.4 114.4 92.1 65.1 82.7 102.7 79.9 194.1 93.2 156.8 173.6 69.3 127.7 137.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.3 0.3 0.0 0.0 0.0 0.4 0.9 0.0 0.0 5.6 1.4 2.3 2.3 2.5 3.2 2.3 2.1 2.3 2.3 2.2 2.0 2.5 2.8 0.6 3.2 0.0 3.3 7.6 1.3 1.2 6.5 0.0 1.4 1.7 2.3 0.6 0.0 1.4 0.0 4.2 32.3 0.4 5.5 0.0 0.8 123.7 3.4 1.3 2.5 0.0 38.3 3.1 0.8 55.9 4.7 10.2 1.8 1.3 19.9 3.3 1.1 20.8 0.0 2.3 7.3 4.1 6.9 3.2 13.9 1.2 7.2 0.0 2.8 0.4 1.1 0.0 1.5 2.3 1.2 0.3 0.7 23.0 2.0 1.5 0.1 1.3 1.3 0.0 2.3 6.1 79.5 13.5 12.2 1.8 3.8 2.5 1.2 17.9 2.0 PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880893-127899224 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 22.6;lymphoid tissue: 14.4;testis: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 65.9;Late spermatids: 87.5;Spermatocytes: 53.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centrosome, Cytosol" "HPA017327: AB_2669584, HPA035026: AB_10602080, HPA043198: AB_2732504" "unprognostic (2.44e-1)" "unprognostic (4.24e-2)" "prognostic favorable (7.46e-5)" "unprognostic (2.18e-1)" "unprognostic (3.79e-1)" "unprognostic (9.20e-2)" "unprognostic (1.06e-5)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.44e-3)" "unprognostic (5.66e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (1.27e-1)" "unprognostic (2.22e-11)" "unprognostic (2.29e-2)" "unprognostic (3.58e-1)" "unprognostic (4.75e-2)" "unprognostic (7.93e-2)" 1.0 1.1 0.4 4.9 0.5 22.6 2.0 0.2 0.7 0.9 0.1 3.5 2.8 1.5 0.6 3.2 1.3 1.1 0.5 0.5 0.6 0.6 0.8 0.9 7.4 0.5 0.5 1.0 0.4 0.6 0.2 3.6 0.4 0.9 4.3 2.1 0.9 0.9 0.1 2.3 2.9 1.8 0.4 1.6 2.0 22.6 0.6 14.4 0.9 0.7 7.3 1.3 1.4 0.4 26.1 12.1 44.3 22.9 1.5 4.2 20.1 24.9 17.6 32.4 33.3 17.0 26.1 34.9 9.0 13.9 26.3 16.7 31.6 19.9 49.6 27.4 13.1 31.6 20.0 16.0 0.5 45.2 35.9 1.4 2.0 29.7 13.6 5.9 25.3 26.3 37.5 45.2 27.6 18.2 69.9 20.1 20.7 26.3 13.6 36.0 30.9 12.1 10.8 16.4 24.4 20.0 15.8 14.2 7.6 18.7 11.5 19.3 11.0 25.3 24.4 17.4 31.4 23.1 27.4 49.0 13.0 33.7 28.7 0.0 0.1 0.4 0.4 0.2 0.3 0.1 0.5 0.5 0.2 0.2 0.1 0.6 0.0 0.4 0.1 0.1 1.2 0.2 0.4 0.5 0.2 0.7 0.5 0.6 0.5 0.5 0.4 0.4 0.6 0.4 1.6 0.0 0.6 0.0 1.6 1.7 0.9 1.7 1.2 1.8 1.0 0.9 0.9 0.0 0.6 1.8 0.0 6.0 1.9 2.0 0.0 0.6 65.9 4.7 1.0 1.0 2.4 19.6 0.8 0.4 12.9 1.6 4.1 2.0 1.3 7.5 0.4 0.5 3.7 0.0 0.8 3.3 6.1 1.3 0.6 87.5 2.8 1.5 0.0 1.0 1.2 1.1 1.0 1.0 1.2 0.1 0.5 0.4 8.7 0.7 0.5 0.6 3.7 0.8 0.0 0.4 3.6 53.5 13.4 6.8 0.9 3.8 2.1 0.8 4.5 1.7 PLP2 "A4, A4-LSB, MGC126187" ENSG00000102007 "Proteolipid protein 2" Q04941 X 49171898-49175235 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 496.5;Exocrine glandular cells: 496.6;Pancreatic endocrine cells: 550.1;Suprabasal keratinocytes: 504.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042415 Approved NA NA 250000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA042415: AB_10796907" "unprognostic (1.40e-1)" "unprognostic (6.67e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.32e-5)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (1.04e-3)" "unprognostic (4.14e-2)" "unprognostic (2.58e-2)" "unprognostic (9.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.55e-10)" "unprognostic (1.66e-1)" "unprognostic (1.25e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 105.1 195.8 17.3 87.6 17.6 358.6 99.8 19.8 21.3 173.6 27.0 164.1 71.0 162.0 42.7 381.7 124.4 53.2 121.0 17.3 24.4 61.3 36.6 118.6 59.9 22.7 21.9 110.3 250.8 37.5 97.4 60.8 20.4 97.8 130.5 6.2 119.3 104.7 99.0 390.6 96.2 156.6 20.2 79.1 114.6 23.3 21.7 77.9 46.8 53.3 148.0 182.8 264.3 19.7 539.1 312.8 0.4 1.0 131.6 388.9 1.6 278.2 223.5 339.9 255.4 115.2 248.4 193.5 68.1 209.2 340.7 444.1 260.5 517.4 214.5 490.2 104.2 71.4 421.1 3.1 210.0 136.0 304.2 174.7 505.6 443.5 516.5 317.6 260.9 63.0 55.1 239.6 249.2 346.0 14.9 346.2 3.3 263.6 456.2 48.9 300.1 563.8 464.6 355.1 69.4 120.6 394.4 155.6 244.4 2.6 340.6 77.0 293.7 194.4 185.4 344.6 472.4 102.2 100.6 50.9 461.3 359.7 464.4 486.8 287.7 148.7 59.9 99.8 100.7 226.4 214.3 112.8 298.5 144.8 107.8 93.4 320.0 70.5 63.7 694.2 265.8 235.8 17.3 17.6 19.8 21.3 17.3 24.4 22.7 21.9 20.4 20.2 21.7 19.7 49.3 73.7 38.2 1.0 160.8 439.7 306.0 496.5 167.9 0.4 67.8 115.4 33.3 57.2 101.9 80.9 0.0 2.7 232.0 134.6 21.5 379.6 16.4 71.8 27.8 63.7 111.7 43.1 0.6 496.6 27.2 110.4 71.9 51.1 88.7 15.4 55.3 12.8 157.5 0.0 0.7 254.9 138.4 130.3 210.5 20.3 169.9 133.3 224.1 4.7 146.4 18.9 35.0 0.0 0.6 550.1 200.3 60.9 148.5 219.5 141.8 9.4 92.9 1.1 124.9 76.1 128.7 4.2 1.4 401.0 504.9 6.4 162.7 29.6 285.2 334.1 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 204.5;Ductal cells: 352.1;Proximal enterocytes: 209.8;Rod photoreceptor cells: 234.9;Urothelial cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 41 "T-cells: 6.6" "Cell line enhanced" "Detected in many" "A549: 144.1;CAPAN-2: 154.6;OE19: 255.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 4.8 13.2 37.7 8.5 61.6 0.0 36.9 57.1 50.0 63.4 26.2 40.5 62.7 16.8 8.4 27.2 81.8 52.4 1.7 38.8 43.5 11.5 3.7 8.3 1.4 57.3 53.6 2.7 37.3 19.5 11.8 3.6 56.2 31.7 32.1 29.6 105.7 32.9 0.6 53.2 51.0 6.4 44.8 4.7 50.3 7.6 49.2 5.2 5.7 0.5 6.0 36.5 14.2 83.9 85.5 144.1 2.1 0.1 0.0 0.3 0.2 8.2 0.0 25.3 18.9 41.7 154.6 0.0 88.3 11.9 0.1 45.3 0.0 17.6 11.1 0.8 2.6 0.0 55.9 0.0 28.6 0.0 5.5 5.2 7.6 12.7 16.7 53.4 4.2 0.0 0.7 0.1 0.0 98.5 0.4 0.1 61.5 255.8 0.0 0.0 0.0 2.4 62.1 13.7 17.4 40.9 23.3 38.3 60.3 5.8 50.0 2.5 4.5 55.7 36.5 0.5 61.9 0.8 101.7 70.4 15.5 0.0 46.9 0.0 0.0 0.0 3.2 0.0 6.6 0.0 1.3 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 37.7 61.6 57.1 50.0 38.8 43.5 57.3 53.6 56.2 44.8 49.2 83.9 17.0 6.4 7.5 0.0 1.5 0.0 134.2 0.0 8.0 19.7 137.1 149.9 0.0 204.5 35.3 22.0 10.4 0.5 2.7 77.0 3.9 352.1 0.3 115.2 9.2 15.2 8.5 0.0 0.0 139.5 15.1 3.0 91.3 90.1 1.3 0.0 0.0 0.5 0.9 16.8 0.0 38.8 0.0 1.0 0.0 1.6 0.0 1.9 0.0 0.0 2.6 21.7 0.0 0.0 0.0 128.8 85.2 0.0 1.6 97.4 209.8 1.4 91.1 234.9 0.0 0.8 2.7 0.6 35.1 20.3 0.0 0.8 3.5 0.1 87.2 205.8 PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 392.7;Hepatic stellate cells: 779.6;Leydig cells: 1092.6;Peritubular cells: 398.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cell line enhanced" "Detected in many" "ASC diff: 710.0;ASC TERT1: 351.8;HSkMC: 438.1;U-2197: 660.4" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" 168.4 53.0 93.9 33.6 94.2 13.1 139.8 87.3 105.9 294.6 50.7 56.7 24.0 107.2 56.2 51.3 122.5 66.3 84.6 88.3 90.6 91.4 182.0 87.0 22.4 107.5 108.1 81.9 36.8 130.2 23.1 225.5 87.7 102.8 41.8 19.0 76.2 169.7 50.9 82.1 45.8 65.6 86.8 23.3 66.0 37.3 113.2 29.8 327.6 63.0 19.9 139.2 142.8 88.6 3.3 10.8 14.1 1.5 710.0 351.8 34.5 39.3 39.7 35.5 17.4 31.8 6.2 5.2 4.6 59.3 39.4 5.9 2.1 0.8 7.4 0.0 9.4 1.3 4.4 44.5 17.3 0.1 0.0 438.1 3.0 34.2 28.6 25.1 34.1 0.4 2.9 0.1 39.0 3.2 0.1 0.5 43.3 9.2 42.6 0.1 0.1 1.7 6.1 32.6 0.4 28.1 12.4 16.1 4.2 42.6 5.2 0.0 21.6 176.2 14.4 660.4 1.8 0.0 0.0 0.0 31.0 1.7 12.7 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 93.9 94.2 87.3 105.9 88.3 90.6 107.5 108.1 87.7 86.8 113.2 88.6 148.5 25.6 18.9 0.0 7.2 0.0 19.8 0.0 35.3 3.9 12.2 31.2 0.0 44.3 13.0 22.0 0.0 127.0 1.1 8.1 21.5 21.5 7.9 13.9 139.4 148.3 2.4 8.0 0.0 9.2 9.8 392.7 5.6 16.3 3.8 8.1 779.6 132.6 38.8 0.0 0.0 8.5 0.0 35.2 0.0 28.3 1092.6 14.9 0.0 0.0 0.9 136.0 0.0 0.0 0.0 7.9 5.9 398.7 7.1 20.8 15.5 21.3 4.4 4.1 138.1 179.7 107.2 4.5 3.4 16.4 0.0 214.9 5.0 22.4 7.2 20.1 PLPPR1 "FLJ20300, LPPR1, MGC26189, PRG-3" ENSG00000148123 "Phospholipid phosphatase related 1" Q8TBJ4 9 101028727-101325135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;kidney: 15.6" "Group enriched" "Detected in some" 4 "Distal tubular cells: 37.2;Early spermatids: 12.3;Proximal tubular cells: 39.0" "Group enriched" "Detected in some" 5 "glioma: 11.1;liver cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Hep G2: 3.7;SCLC-21H: 9.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014760, HPA014968, HPA014979" Supported Supported Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA014760: AB_2669084, HPA014968: AB_1855702, HPA014979: AB_2669130" "unprognostic (1.08e-2)" "unprognostic (2.79e-1)" "unprognostic (2.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (7.33e-2)" "unprognostic (3.41e-1)" "prognostic favorable (1.37e-4)" "unprognostic (2.09e-1)" "unprognostic (1.14e-1)" "unprognostic (9.86e-4)" "unprognostic (1.44e-1)" "unprognostic (1.65e-6)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (2.85e-1)" "unprognostic (4.83e-2)" 0.0 0.1 9.7 0.0 12.8 0.0 0.7 7.1 12.7 0.1 5.2 0.2 0.0 0.0 2.8 0.0 0.2 0.0 0.0 10.4 9.3 15.6 3.6 1.4 0.0 10.2 9.1 0.0 0.3 0.0 0.1 0.0 9.8 0.2 0.1 1.5 0.3 0.0 0.0 0.1 0.0 0.0 9.6 0.0 0.1 0.6 10.9 0.4 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 9.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 12.8 7.1 12.7 10.4 9.3 10.2 9.1 9.8 9.6 10.9 11.5 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.3 2.3 0.0 1.5 0.6 0.0 0.0 0.0 0.1 0.0 37.2 0.0 12.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.0 39.0 0.0 1.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 PLS3 T-plastin ENSG00000102024 "Plastin 3" P13797 X 115561174-115650861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 209.3;Alveolar cells type 1: 211.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "NK-cell: 3.7;plasmacytoid DC: 12.2" "Group enriched" "Detected in many" 6 "dendritic cells: 12.2;NK-cells: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020433, HPA076083" Approved Approved "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA020433: AB_2670440, HPA076083: AB_2686773" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "unprognostic (6.10e-2)" "unprognostic (4.37e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (6.07e-5)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (5.15e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.72e-4)" "prognostic unfavorable (7.04e-4)" 120.8 32.4 33.2 36.3 40.6 1.4 71.4 44.3 43.6 83.7 22.1 46.4 21.8 120.5 76.2 117.8 68.3 83.1 57.9 30.7 34.9 113.2 202.0 139.8 24.2 43.5 40.1 101.5 31.4 12.7 11.7 78.4 42.2 43.6 31.8 11.9 46.8 103.2 31.4 119.5 25.0 119.4 38.4 99.8 37.7 22.3 39.5 27.2 175.0 48.8 41.9 75.4 88.5 47.9 206.2 207.1 176.8 51.5 174.3 161.7 269.3 208.2 233.1 194.5 233.9 225.0 167.2 0.8 590.0 171.9 140.6 256.7 190.5 339.1 314.2 2.9 235.8 19.4 234.6 95.0 157.5 0.1 9.6 103.1 159.5 302.7 211.1 315.3 429.5 16.8 0.5 0.3 188.9 59.7 0.4 2.3 234.6 88.0 243.2 0.4 117.8 4.9 233.1 109.1 0.6 36.9 436.8 107.9 89.7 253.7 60.2 3.0 474.3 314.5 53.9 324.6 422.8 7.8 30.5 4.2 137.6 0.8 133.4 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.4 0.0 0.1 0.0 0.1 3.7 0.0 12.2 1.4 0.2 33.2 40.6 44.3 43.6 30.7 34.9 43.5 40.1 42.2 38.4 39.5 47.9 209.3 211.5 88.6 26.8 2.0 124.9 121.4 79.6 48.9 0.2 5.6 25.4 17.9 24.3 79.4 99.3 0.0 4.0 1.6 3.5 13.7 59.0 8.4 33.0 39.4 130.5 13.2 4.4 12.3 53.8 105.3 74.3 31.1 64.1 0.0 60.5 64.2 92.1 3.9 0.0 47.6 6.9 38.7 5.0 21.7 8.0 51.9 3.0 56.9 40.3 0.6 26.4 0.0 1.5 97.9 68.6 6.5 82.8 1.6 80.7 2.2 22.0 31.2 1.5 52.6 19.8 132.3 1.2 17.7 65.5 134.1 4.5 3.6 131.1 11.1 100.6 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PLSCR4 ENSG00000114698 "Phospholipid scramblase 4" Q9NRQ2 3 146192335-146251179 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 77.3;Astrocytes: 151.1;Endothelial cells: 63.4;Hepatic stellate cells: 110.3;Oligodendrocyte precursor cells: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.5;ASC TERT1: 48.2;hTERT-RPE1: 62.1;HUVEC TERT2: 50.8;TIME: 106.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002276 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA002276: AB_1855479" "unprognostic (3.73e-3)" "unprognostic (4.03e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.62e-1)" "unprognostic (6.77e-3)" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (7.33e-2)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-4)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" "unprognostic (8.13e-3)" "unprognostic (2.97e-3)" 60.2 43.8 30.2 9.4 28.2 2.3 41.9 30.9 32.5 28.9 11.6 27.4 6.8 30.1 15.7 23.2 41.2 45.6 28.0 28.7 38.5 25.3 69.0 37.4 10.5 39.3 44.0 36.4 20.5 4.3 11.2 56.4 32.6 13.8 25.2 13.7 23.6 25.8 7.4 16.1 13.6 33.7 36.9 30.1 14.4 21.6 41.8 6.6 31.2 18.8 6.7 19.8 25.5 32.2 0.0 9.9 1.7 0.0 60.5 48.2 0.3 11.5 15.7 5.0 10.9 1.0 12.6 0.0 12.3 21.0 5.0 1.4 2.4 1.1 2.8 0.1 0.1 5.0 7.9 1.3 28.1 0.1 1.3 29.6 1.6 10.4 3.0 62.1 50.8 0.0 0.2 0.9 7.4 0.3 0.0 0.1 2.1 5.1 3.4 0.0 0.8 0.0 0.1 0.0 0.6 0.0 20.1 0.1 3.9 2.5 0.7 0.6 106.4 10.4 2.6 23.6 2.1 0.3 0.0 0.0 2.6 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 28.2 30.9 32.5 28.7 38.5 39.3 44.0 32.6 36.9 41.8 32.2 77.3 3.2 10.3 151.1 1.0 10.8 5.6 0.8 12.0 0.6 10.2 8.6 4.1 25.8 6.0 3.7 0.0 0.7 0.3 27.4 0.0 8.2 1.1 3.6 11.6 63.4 10.3 15.6 1.7 11.6 0.5 57.1 2.0 1.5 1.3 7.0 110.3 44.1 0.8 0.0 0.6 11.7 0.0 7.1 11.8 3.8 42.9 1.1 3.6 40.3 0.1 51.4 0.0 61.3 0.6 4.7 13.3 32.4 2.8 2.6 6.4 28.3 6.4 1.5 0.0 18.9 23.6 1.2 0.9 4.8 8.7 0.8 1.8 20.0 8.1 2.7 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PLXNC1 "CD232, VESPR" ENSG00000136040 "Plexin C1" O60486 12 94148577-94307675 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 57.0;Macrophages: 62.5;Melanocytes: 96.0;monocytes: 53.8" "Cancer enhanced" "Detected in all" "melanoma: 24.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.4" "Group enriched" "Detected in all" 4 "granulocytes: 16.4;monocytes: 8.6" "Cell line enhanced" "Detected in many" "HAP1: 33.3;Karpas-707: 25.8;SK-MEL-30: 41.4;U-266/70: 64.3;U-266/84: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066899 Approved Mitochondria NA NA 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA066899: AB_2685743" "unprognostic (1.49e-1)" "unprognostic (4.01e-2)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" "unprognostic (3.24e-2)" "unprognostic (4.67e-3)" "unprognostic (2.80e-2)" "unprognostic (3.49e-1)" "unprognostic (4.64e-2)" "unprognostic (1.78e-2)" "unprognostic (2.38e-1)" "unprognostic (4.02e-2)" "unprognostic (5.33e-3)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (5.48e-2)" 6.1 8.8 6.4 20.5 7.1 17.4 4.7 8.9 7.5 8.5 1.9 5.7 4.1 7.0 2.7 3.8 4.8 10.2 1.9 7.1 15.9 4.0 2.5 11.4 16.2 5.3 12.7 14.8 2.4 0.9 4.1 9.4 4.7 2.3 6.5 2.2 2.3 4.5 4.0 8.3 5.5 6.9 4.2 19.8 4.5 15.2 18.6 5.7 3.4 4.1 13.0 9.5 3.8 8.7 1.1 0.4 2.7 0.5 1.5 1.2 0.4 1.3 1.8 1.7 5.1 9.1 0.1 21.8 0.1 2.0 1.6 0.1 33.3 1.4 1.2 15.3 0.7 1.2 0.6 6.1 17.7 4.5 7.2 17.7 0.0 1.9 0.8 2.3 0.0 2.0 0.6 25.8 0.5 0.3 1.0 2.4 5.5 0.2 1.2 3.6 1.0 12.1 0.1 1.7 2.2 1.6 0.3 0.2 41.4 6.3 0.1 3.7 0.7 0.6 2.3 0.2 0.8 64.3 73.3 1.4 0.4 11.7 1.4 0.0 3.6 15.1 1.6 6.1 1.7 2.6 1.7 1.9 2.9 1.7 1.6 1.6 16.4 1.1 8.6 1.1 1.3 2.0 6.4 7.1 8.9 7.5 7.1 15.9 5.3 12.7 4.7 4.2 18.6 8.7 4.9 3.2 2.4 9.8 17.9 6.1 0.3 0.3 1.2 3.6 3.2 2.5 8.1 1.5 0.2 0.0 0.0 0.2 5.6 1.2 1.9 0.2 9.4 3.2 14.9 4.3 19.8 26.1 36.1 0.5 0.2 16.0 1.1 1.6 16.5 29.8 6.1 1.6 18.8 0.0 57.0 1.8 0.0 39.4 13.8 6.2 1.5 62.5 96.0 40.3 53.8 0.3 3.1 34.2 12.6 0.3 1.8 3.4 24.4 0.2 0.1 3.4 2.3 0.5 6.6 2.8 2.5 3.0 1.1 0.7 1.6 0.1 9.4 4.8 1.9 0.3 PM20D1 "Cps1, FLJ32569" ENSG00000162877 "Peptidase M20 domain containing 1" Q6GTS8 1 205828025-205850132 "Enzymes, Predicted secreted proteins" "Hydrolase, Lyase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pancreas: 78.0;skin 1: 33.8" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 20.9;Gastric mucus-secreting cells: 7.1;Proximal tubular cells: 7.1" "Cancer enriched" "Detected in some" 32 "urothelial cancer: 30.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "Cell line enriched" "Detected in single" 9 "Karpas-707: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to digestive system" NA NA 3300000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (4.83e-1)" "unprognostic (4.08e-3)" "unprognostic (1.17e-3)" "unprognostic (3.11e-1)" "unprognostic (1.20e-1)" "unprognostic (5.50e-2)" "unprognostic (5.81e-2)" "unprognostic (4.57e-2)" "unprognostic (7.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (1.68e-2)" 0.8 0.0 0.2 0.1 0.2 0.0 1.2 0.0 0.3 0.1 1.2 0.1 0.1 0.1 0.5 0.0 0.4 0.0 0.3 0.2 0.3 6.3 0.2 0.2 1.1 0.3 0.3 0.3 78.0 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.0 0.0 0.0 33.8 0.1 0.0 0.2 1.0 2.9 0.0 0.3 0.1 0.1 0.0 0.4 2.2 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.3 0.0 0.5 0.1 0.4 1.3 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 2.2 0.3 0.2 0.2 0.0 0.3 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.3 0.8 0.0 0.0 1.6 1.1 0.0 0.0 0.0 0.6 0.5 0.0 0.0 1.5 0.0 0.0 0.0 2.1 0.0 0.9 0.1 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.4 3.2 20.9 0.3 0.5 7.1 0.0 0.0 0.0 0.7 0.3 0.1 0.0 3.5 0.2 0.0 1.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.0 1.5 1.5 0.6 0.0 0.0 1.8 0.2 0.0 7.1 0.0 0.8 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.9 2.4 0.0 0.1 PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 803.1;Endometrial ciliated cells: 463.6;Glandular and luminal cells: 529.8;Squamous epithelial cells: 474.5;Suprabasal keratinocytes: 691.2;Urothelial cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 169.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 169.8" "Cell line enhanced" "Detected in many" "GAMG: 207.5;U-138 MG: 202.1" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA051063: AB_2681330" "unprognostic (1.35e-3)" "unprognostic (5.02e-2)" "unprognostic (5.57e-2)" "unprognostic (4.88e-2)" "unprognostic (6.65e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.41e-2)" "unprognostic (6.12e-2)" "unprognostic (8.47e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.53e-1)" "unprognostic (7.68e-2)" "unprognostic (8.74e-2)" "unprognostic (1.09e-1)" 2.0 0.7 2.8 8.0 2.7 88.1 3.9 2.6 5.1 6.5 3.0 2.5 3.7 5.4 0.2 13.7 2.9 8.0 0.9 2.6 2.8 2.3 2.1 3.8 14.7 2.8 2.7 0.7 1.2 14.8 16.7 13.4 3.0 3.6 3.4 2.0 3.6 1.3 1.5 24.1 3.9 1.9 2.7 4.6 2.5 3.1 3.7 12.1 2.1 1.5 14.2 17.3 7.9 2.4 26.6 17.4 5.2 1.6 8.8 69.0 19.8 125.4 84.1 71.5 70.7 1.7 32.5 104.6 17.0 23.5 207.5 38.4 21.0 11.8 70.4 33.7 154.5 19.4 26.0 4.6 87.6 67.1 28.2 28.7 30.8 93.8 48.5 26.1 24.0 46.7 26.7 17.5 24.1 2.6 53.8 20.1 151.7 2.7 32.7 54.1 28.8 39.1 41.9 24.2 39.7 32.7 6.1 3.2 71.5 56.1 5.3 54.6 90.6 202.1 54.0 10.3 141.4 2.8 0.3 92.1 16.8 37.6 48.5 169.8 16.7 103.6 10.9 26.2 9.6 33.8 5.0 6.8 12.1 25.0 4.1 5.9 53.5 6.3 32.1 10.2 25.2 15.1 2.8 2.7 2.6 5.1 2.6 2.8 2.8 2.7 3.0 2.7 3.7 2.4 29.2 32.1 25.7 0.7 175.3 803.1 316.2 236.4 415.4 0.2 111.8 82.0 4.7 12.8 129.6 3.7 2.1 120.3 125.3 141.1 0.0 54.7 0.8 463.6 48.8 48.5 133.4 5.5 0.0 67.0 14.7 32.9 168.2 529.8 31.8 11.8 7.9 0.5 89.5 0.0 0.0 146.8 181.0 37.2 363.3 1.1 0.9 140.6 74.7 7.5 142.4 0.3 34.0 0.0 0.2 100.1 123.6 1.2 63.1 265.7 94.7 0.5 101.5 0.7 0.0 10.8 32.0 0.3 19.8 474.5 691.2 315.2 117.0 19.8 122.2 569.2 PMEL "D12S53E, gp100, Pmel17, SI, SIL, SILV" ENSG00000185664 "Premelanosome protein" P40967 12 55954105-55973317 "Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "cervix: 80.5;endometrium 1: 32.2;skin 1: 115.2" "Cell type enriched" "Detected in many" 32 "Melanocytes: 1472.7" "Cancer enriched" "Detected in many" 500 "melanoma: 2481.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 68 "SK-MEL-30: 8590.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031649 Enhanced Supported "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA 11000000 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "Golgi apparatus" "HPA031649: AB_2673976" "unprognostic (4.63e-1)" "unprognostic (8.93e-2)" "unprognostic (1.53e-1)" "unprognostic (1.60e-1)" "unprognostic (5.90e-2)" "unprognostic (6.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-3)" "unprognostic (6.44e-2)" "unprognostic (1.21e-1)" "unprognostic (5.12e-2)" "unprognostic (3.98e-1)" "prognostic favorable (3.70e-4)" "unprognostic (2.86e-2)" "unprognostic (1.54e-1)" "unprognostic (7.60e-2)" "unprognostic (1.04e-1)" 3.3 0.8 0.2 0.8 0.2 1.8 8.3 0.7 0.5 80.5 0.3 1.3 1.6 32.2 1.5 0.7 1.2 1.6 0.6 0.3 0.0 2.1 5.0 0.9 5.6 0.0 0.4 4.3 2.3 1.7 0.7 2.8 0.1 0.9 1.2 0.4 3.5 0.8 0.3 115.2 2.1 3.5 0.0 0.5 1.1 4.8 0.0 0.7 1.1 0.2 2.2 1.3 4.0 0.3 14.8 1.1 5.6 0.2 83.6 0.6 126.2 0.9 0.8 1.9 2.0 12.8 6.0 2.6 6.1 0.8 0.3 2.5 0.6 1.0 1.6 3.0 2.1 2.4 2.5 0.7 0.3 1.0 1.4 0.5 1.0 1.2 0.6 1.3 1.0 1.1 0.5 1.8 0.5 2.7 0.4 1.0 17.1 2.8 0.3 1.6 3.5 1.5 1.4 2.7 0.5 2.6 0.3 2.5 8590.9 4.6 4.4 8.8 1.4 0.9 6.5 0.7 7.9 2.1 10.4 3.2 1.0 2.7 0.3 0.0 0.3 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.4 0.0 0.1 0.2 0.2 0.7 0.5 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.8 0.0 0.5 0.0 0.1 45.9 0.8 1.1 2.8 0.0 1.0 0.9 0.4 1.5 2.2 0.0 0.0 12.1 0.0 1.5 0.0 2.1 8.0 0.7 0.2 1.2 0.0 0.8 0.1 2.3 12.4 1.6 1.1 0.5 0.0 11.1 0.0 2.9 1.7 0.0 0.1 1.6 0.0 0.3 14.6 5.3 12.2 0.6 1472.7 1.0 0.6 0.2 0.0 0.0 0.1 1.0 0.6 0.7 1.2 0.5 2.4 2.8 1.0 0.0 0.0 0.2 1.7 3.9 2.6 1.0 10.2 24.9 0.4 1.3 1.6 0.4 PMFBP1 ENSG00000118557 "Polyamine modulated factor 1 binding protein 1" Q8TBY8 16 72112157-72176878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 20.9" "Group enriched" "Detected in some" 6 "Early spermatids: 115.6;Late spermatids: 259.5" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "pons: 13.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 21.0;SH-SY5Y: 10.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA056716, HPA075825" Approved Uncertain "Endoplasmic reticulum" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA056716: AB_2683215, HPA075825: " "unprognostic (1.46e-1)" "unprognostic (3.62e-1)" "unprognostic (5.95e-2)" "unprognostic (1.04e-1)" "unprognostic (2.44e-2)" "unprognostic (7.03e-2)" "unprognostic (1.06e-4)" "unprognostic (1.60e-1)" "unprognostic (3.81e-1)" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (2.68e-5)" "unprognostic (9.85e-2)" "unprognostic (2.66e-1)" "unprognostic (9.85e-2)" "unprognostic (8.67e-2)" 1.7 2.2 0.4 1.3 0.9 4.5 1.5 2.5 0.8 1.8 0.5 3.2 2.9 1.7 13.5 2.9 2.0 0.9 3.3 0.8 1.9 3.0 3.1 1.6 2.0 3.5 3.9 2.6 6.5 1.2 2.7 0.6 13.3 3.6 3.3 3.5 1.7 0.3 0.6 4.4 3.9 0.3 1.9 4.7 2.6 20.9 1.0 2.4 2.1 0.0 0.5 1.8 1.9 1.4 0.2 0.4 2.8 2.8 0.0 0.6 1.9 0.6 0.2 0.6 2.1 1.1 2.8 1.9 0.4 0.1 0.1 1.8 1.0 0.1 1.4 0.2 4.3 1.9 3.7 3.1 0.0 4.2 3.2 0.0 0.9 0.1 2.1 0.6 0.8 2.3 0.4 1.7 0.1 2.4 1.1 6.8 0.8 0.1 1.2 2.9 0.2 1.5 0.3 0.8 21.0 10.7 0.0 0.0 0.2 2.0 0.5 2.7 1.8 1.3 2.2 0.6 1.4 3.9 1.5 1.2 0.6 2.8 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.4 0.9 2.5 0.8 0.8 1.9 3.5 3.9 13.3 1.9 1.0 1.4 0.0 0.0 0.6 1.0 0.3 0.4 0.1 0.1 1.2 0.9 0.1 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.1 0.3 0.0 0.2 115.6 0.3 0.2 0.3 5.4 0.8 0.7 0.2 0.1 0.6 0.0 0.1 3.8 0.3 0.0 0.1 4.7 30.3 0.7 0.7 0.0 1.9 5.5 259.5 1.2 2.4 0.0 1.0 0.0 1.1 0.0 1.0 1.6 0.1 0.1 1.5 0.0 0.1 0.2 0.6 1.6 0.2 0.0 0.0 0.1 2.9 0.9 0.3 0.0 0.1 1.0 0.0 0.9 0.2 PMS2 "H_DJ0042M02.9, HNPCC4, MLH4, PMSL2" ENSG00000122512 "PMS1 homolog 2, mismatch repair system component" P54278 7 5970925-6009106 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010235, HPA066490, HPA070310" Approved Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "CAB010235: AB_2167281, HPA066490: AB_2685677, HPA070310: AB_2686250" "unprognostic (5.13e-2)" "unprognostic (6.55e-3)" "unprognostic (1.54e-1)" "unprognostic (1.43e-3)" "unprognostic (5.14e-2)" "unprognostic (1.29e-1)" "unprognostic (7.36e-2)" "unprognostic (1.02e-1)" "unprognostic (7.43e-2)" "unprognostic (2.35e-1)" "unprognostic (1.86e-1)" "unprognostic (7.38e-2)" "prognostic favorable (1.23e-5)" "unprognostic (5.31e-2)" "unprognostic (2.01e-2)" "unprognostic (3.67e-2)" "unprognostic (2.81e-2)" 5.3 5.1 6.7 5.3 7.2 5.8 6.5 6.3 7.6 4.8 2.8 4.8 5.7 4.9 5.0 5.3 5.7 4.0 4.1 7.4 5.8 10.4 4.7 4.4 8.4 5.3 5.6 5.7 3.9 11.0 4.6 4.8 5.5 5.2 4.7 8.4 5.7 5.5 4.5 11.9 5.3 5.3 4.4 5.9 5.0 4.0 5.2 8.8 9.2 3.5 8.9 5.1 4.9 7.0 15.1 16.7 12.9 32.2 9.0 13.6 10.9 7.8 5.8 6.6 5.6 14.0 9.9 28.2 8.7 10.9 17.2 19.6 19.2 6.6 8.0 11.3 7.2 12.0 12.5 10.1 15.9 15.8 9.4 15.1 14.8 5.4 22.3 11.4 13.7 15.2 22.9 12.6 11.9 15.5 5.2 17.1 13.3 7.6 9.6 16.3 15.3 14.0 16.4 11.0 11.9 25.7 13.3 23.0 16.2 18.0 27.1 11.8 12.4 9.3 21.2 14.2 14.6 19.8 32.8 27.5 7.2 15.3 22.9 5.0 2.9 1.9 4.5 4.1 4.9 3.4 3.5 3.8 3.0 3.4 4.4 3.4 1.4 2.3 1.8 3.1 3.4 3.4 6.7 7.2 6.3 7.6 7.4 5.8 5.3 5.6 5.5 4.4 5.2 7.0 12.2 12.8 8.2 11.4 13.6 5.0 9.3 10.9 15.9 13.2 10.7 11.3 3.2 12.8 9.7 11.0 22.9 9.4 15.2 1.8 35.2 5.5 9.9 11.0 14.6 10.1 5.4 8.4 14.0 3.3 6.3 6.6 8.2 11.8 5.1 11.4 7.9 7.6 5.2 30.3 12.2 2.2 10.2 7.1 5.9 6.6 12.8 6.3 7.2 5.6 8.7 7.8 20.6 3.5 8.3 4.7 2.6 10.1 9.6 12.6 2.2 39.5 9.3 14.3 26.3 10.0 8.0 34.5 11.7 10.5 8.1 12.7 11.4 11.9 2.6 11.1 PMVK "HUMPMKI, PMK, PMKA" ENSG00000163344 "Phosphomevalonate kinase" Q15126 1 154924740-154936719 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 266.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029900 Approved NA NA 15000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA029900: AB_10601390" "unprognostic (2.52e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.31e-1)" "unprognostic (1.81e-2)" "unprognostic (8.13e-2)" "unprognostic (5.47e-2)" "unprognostic (8.22e-2)" "prognostic favorable (9.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "prognostic favorable (4.96e-4)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" 39.9 56.4 99.0 29.8 100.1 15.3 35.0 97.9 108.9 33.4 95.0 39.9 45.9 25.9 17.7 77.7 37.2 17.2 63.1 93.9 96.4 53.8 91.9 30.1 34.6 98.6 97.4 35.8 41.6 58.2 60.3 23.7 96.0 32.4 22.2 19.8 34.0 27.1 79.1 69.2 44.2 27.7 96.4 45.7 40.5 26.6 102.3 27.9 31.5 47.4 36.8 31.9 37.9 99.8 51.8 72.9 46.7 72.5 43.6 30.9 48.5 40.5 29.3 38.9 37.0 30.6 101.0 75.1 75.9 49.3 40.5 49.4 65.3 63.9 17.8 103.3 28.9 34.1 104.1 29.0 40.0 51.4 29.3 36.3 58.7 70.2 49.6 19.5 40.0 65.9 36.8 221.7 41.3 108.3 40.8 51.0 41.0 121.7 95.0 60.3 29.8 171.1 66.1 38.4 37.7 91.1 44.1 75.7 51.9 35.0 146.7 91.1 32.7 35.8 29.2 84.4 62.1 174.0 153.2 131.8 58.9 83.9 46.7 28.0 80.9 91.8 68.2 205.6 110.1 114.8 93.1 70.6 93.6 111.1 59.1 59.1 6.9 59.7 219.4 96.5 134.3 80.0 99.0 100.1 97.9 108.9 93.9 96.4 98.6 97.4 96.0 96.4 102.3 99.8 22.7 57.7 37.5 9.4 42.2 69.8 105.9 95.8 51.8 38.5 67.1 68.3 57.3 78.6 42.2 53.3 8.4 235.7 31.5 65.0 266.1 69.6 9.0 45.0 28.5 29.8 66.4 35.6 5.1 71.3 108.1 45.1 46.9 44.2 22.2 49.8 39.3 146.9 141.0 37.0 7.0 78.9 67.1 67.9 49.5 13.5 42.6 47.8 65.8 3.7 49.5 119.1 41.2 8.0 11.8 61.7 61.7 47.8 58.8 53.7 219.3 246.1 22.1 27.4 32.9 46.0 48.4 51.3 51.3 81.0 90.5 227.7 45.1 162.6 79.9 76.2 PNLDC1 "dJ195P10.2, FLJ40240" ENSG00000146453 "PARN like, ribonuclease domain containing 1" Q8NA58 6 159800249-159820704 "Enzymes, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.2;testis: 8.1" "Cell type enhanced" "Detected in some" "Early spermatids: 19.9;Late spermatids: 13.6;Spermatocytes: 14.3;Spermatogonia: 13.3" "Cancer enhanced" "Detected in many" "testis cancer: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052026 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA052026: AB_2681699" "unprognostic (1.58e-1)" "unprognostic (3.88e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-3)" "unprognostic (8.47e-3)" "unprognostic (3.55e-2)" "unprognostic (2.04e-1)" "unprognostic (4.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.37e-2)" "unprognostic (4.19e-1)" "unprognostic (9.98e-2)" "unprognostic (2.69e-9)" "unprognostic (1.14e-2)" "unprognostic (2.25e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-1)" 0.2 0.2 2.1 0.1 3.7 0.1 0.5 2.5 10.2 0.1 1.6 0.3 0.0 0.1 0.0 0.2 1.9 0.0 0.2 2.2 2.0 0.2 0.5 0.2 0.4 1.9 1.9 0.4 1.7 0.0 0.3 0.0 3.0 0.3 0.0 0.1 0.1 0.0 0.1 1.1 0.1 0.0 1.8 0.4 0.2 8.1 2.3 0.2 0.2 0.0 0.2 0.2 0.2 2.7 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.1 3.7 2.5 10.2 2.2 2.0 1.9 1.9 3.0 1.8 2.3 2.7 0.1 0.0 0.0 0.3 0.2 0.3 0.0 0.3 0.0 0.0 0.3 0.5 0.3 4.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 3.8 19.9 2.1 0.1 0.1 0.0 0.0 1.5 0.9 0.0 0.2 0.0 0.1 4.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.8 13.6 0.3 0.1 0.0 3.7 0.0 0.0 0.0 0.5 1.3 1.3 0.0 0.0 0.0 0.1 0.0 0.9 2.7 0.0 0.0 0.5 0.2 14.3 13.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 PNLIPRP3 ENSG00000203837 "Pancreatic lipase related protein 3" Q17RR3 10 116427847-116477957 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 9.0;skin 1: 14.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.1;Early spermatids: 1.5;Late spermatids: 1.9;Melanocytes: 1.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "hTCEpi: 320.3" "Not detected" "Not detected" "HPA046202, HPA052009" Uncertain "Secreted - unknown location" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA046202: AB_10959739, HPA052009: AB_2681692" "unprognostic (2.62e-4)" "unprognostic (1.60e-1)" "unprognostic (6.97e-2)" 2.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 320.3 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 PNPLA1 "dJ50J22.1, FLJ38755" ENSG00000180316 "Patatin like phospholipase domain containing 1" Q8N8W4 6 36243203-36313955 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 23.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;granulocytes: 4.5;Oligodendrocyte precursor cells: 1.5;Proximal enterocytes: 1.5;Proximal tubular cells: 3.8;Suprabasal keratinocytes: 3.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 69.8;eosinophil: 18.9" "Lineage enriched" "Detected in many" 17 "granulocytes: 69.8" "Cell line enriched" "Detected in some" 4 "U-937: 17.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.57e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-4)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (7.37e-2)" "unprognostic (2.49e-1)" "unprognostic (8.89e-2)" "unprognostic (1.13e-2)" "unprognostic (2.95e-1)" "unprognostic (2.76e-2)" "unprognostic (2.70e-2)" "unprognostic (9.85e-2)" "unprognostic (2.06e-1)" "unprognostic (2.04e-2)" "unprognostic (1.65e-2)" 0.1 0.2 0.1 0.6 0.2 4.3 0.6 0.3 0.4 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 4.7 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 23.9 0.9 0.2 0.1 0.7 1.7 1.0 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 17.6 0.0 69.8 4.0 18.9 0.0 2.2 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.2 6.2 0.1 1.1 0.0 0.0 1.1 0.1 0.2 0.3 0.4 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.3 0.0 0.0 0.0 1.0 0.0 0.9 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.2 4.5 0.7 0.0 0.0 0.2 0.0 1.2 0.4 0.0 0.0 0.3 1.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 1.5 0.7 0.1 0.0 0.0 0.0 0.1 1.5 3.8 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 3.7 0.1 0.0 0.4 0.2 0.2 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 31.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 35.9;Cone photoreceptor cells: 18.8;Hepatocytes: 42.3;Rod photoreceptor cells: 37.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 16.7;LHCN-M2: 19.3" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.6 0.2 0.6 0.5 0.8 0.1 1.6 0.1 1.2 0.6 5.9 0.1 0.8 0.3 0.1 0.2 0.9 0.4 0.2 1.2 0.7 4.5 31.0 0.8 0.3 1.7 1.8 0.3 0.0 0.2 0.0 0.3 2.0 0.0 0.1 6.4 0.7 0.0 1.7 5.8 0.5 0.0 0.2 0.4 0.2 0.4 1.3 0.1 0.1 0.1 0.2 0.0 0.3 0.6 5.1 1.6 16.7 6.8 4.6 5.2 0.5 3.1 1.8 4.1 8.8 5.0 9.0 0.0 2.5 5.2 2.4 4.3 10.6 5.0 3.4 0.0 0.9 0.3 4.5 9.4 7.5 0.0 0.3 6.0 3.8 13.2 0.6 7.0 0.5 0.2 0.0 0.0 19.3 0.7 0.3 0.0 11.5 0.6 0.0 0.1 8.9 0.2 1.7 0.2 1.5 0.1 3.4 1.4 4.8 2.9 5.3 5.8 0.6 1.6 4.9 0.1 0.1 0.1 0.0 0.0 14.3 0.1 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.8 0.1 1.2 1.2 0.7 1.7 1.8 2.0 0.2 1.3 0.6 0.4 0.0 0.0 4.2 0.2 0.4 0.5 2.4 0.0 35.9 0.5 0.1 1.3 10.0 1.4 0.0 18.8 0.0 0.2 0.2 0.0 0.4 0.0 1.5 0.5 0.4 1.8 0.0 1.9 0.0 0.1 0.5 0.0 3.6 0.0 1.9 0.7 42.3 0.7 0.0 1.2 0.8 0.0 2.8 0.3 0.3 0.3 0.9 1.8 0.0 0.0 1.1 0.0 0.0 0.8 2.6 0.0 0.7 0.0 0.7 0.4 5.0 0.1 37.3 0.0 1.0 0.8 0.6 0.6 0.0 0.1 0.0 0.2 1.6 0.4 0.4 PNPLA5 "dJ388M5.4, GS2L" ENSG00000100341 "Patatin like phospholipase domain containing 5" Q7Z6Z6 22 43879678-43892013 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;epididymis: 1.7;skin 1: 3.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.2;Inhibitory neurons: 2.1;Late spermatids: 2.1" "Cancer enriched" "Detected in single" 4 "thyroid cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.4;RPMI-8226: 2.7" "Not detected" "Not detected" "HPA050409, HPA054211" Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA050409: AB_2681118, HPA054211: AB_2682418" "unprognostic (6.69e-5)" "unprognostic (3.53e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-2)" "unprognostic (3.33e-3)" "unprognostic (1.05e-1)" "unprognostic (1.50e-1)" "unprognostic (4.31e-2)" 0.0 0.0 0.8 0.1 3.4 0.3 0.3 0.2 2.3 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.1 0.0 1.4 0.5 0.0 0.9 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.8 3.4 0.2 2.3 1.4 0.5 1.2 0.6 0.4 0.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 POC1A "DKFZP434C245, WDR51A" ENSG00000164087 "POC1 centriolar protein A" Q8NBT0 3 52075226-52154690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Dwarfism, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12.8;testis: 17.6" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Extravillous trophoblasts: 33.8;Late spermatids: 73.4;Spermatocytes: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040600 Approved NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA040600: AB_10672837" "unprognostic (2.68e-1)" "unprognostic (7.17e-2)" "prognostic favorable (1.78e-4)" "unprognostic (5.08e-2)" "unprognostic (3.61e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-3)" "unprognostic (2.41e-2)" "unprognostic (7.23e-3)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (9.43e-7)" "unprognostic (9.90e-3)" "unprognostic (1.96e-1)" "unprognostic (3.62e-2)" "unprognostic (2.32e-2)" 1.4 4.1 1.5 4.0 1.5 11.1 2.2 1.4 1.8 1.5 1.1 5.9 4.8 1.0 1.0 4.7 1.7 1.1 1.4 1.7 1.6 2.1 5.2 1.9 5.4 1.9 1.6 0.7 0.9 1.1 0.7 4.1 1.8 1.3 6.0 0.4 1.3 1.0 1.5 2.6 4.0 2.9 1.5 2.8 2.8 17.6 1.6 12.8 1.0 1.0 7.0 2.0 1.8 1.8 30.1 25.2 25.0 33.5 5.1 6.5 33.9 30.0 28.7 62.8 48.7 22.1 31.0 31.3 8.8 23.9 48.6 18.3 38.0 33.9 45.3 26.0 16.0 21.4 26.3 23.9 1.4 24.5 13.0 3.6 7.3 49.6 25.9 8.7 29.0 46.2 18.8 32.9 37.5 23.8 45.6 44.2 19.1 33.7 41.0 19.6 19.7 30.0 14.2 21.0 11.6 16.7 24.0 23.7 18.3 26.0 29.2 45.7 9.7 28.6 27.6 46.3 49.3 27.8 49.1 26.6 19.2 42.6 29.1 0.0 1.6 0.0 1.2 2.2 0.1 0.9 0.8 0.4 1.9 0.5 0.7 0.4 0.5 1.4 1.6 1.9 2.6 1.1 1.5 1.5 1.4 1.8 1.7 1.6 1.9 1.6 1.8 1.5 1.6 1.8 0.9 0.0 1.3 0.3 2.5 1.7 1.6 4.7 0.0 0.7 2.1 2.2 0.7 0.0 1.4 1.8 0.0 21.8 0.9 4.4 0.0 1.8 47.9 4.5 1.0 2.9 1.8 15.6 2.3 3.0 33.8 3.4 2.0 1.5 0.0 11.3 1.8 4.2 12.9 1.7 1.4 5.4 0.0 2.6 3.4 73.4 1.2 2.6 1.8 1.9 2.7 0.8 1.0 0.0 2.7 2.1 2.2 0.4 12.9 1.3 3.0 3.2 4.2 0.0 0.0 1.1 3.4 40.1 21.2 4.9 1.8 7.5 1.6 4.4 8.4 2.1 PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Fibroblasts: 123.5;Leydig cells: 268.7;Peritubular cells: 261.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "ASC diff: 23.0;BJ: 39.2;fHDF/TERT166: 23.9;HHSteC: 94.1;U-2197: 46.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 910000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" 191.0 14.3 9.1 13.3 8.2 0.2 116.3 6.4 8.7 106.1 7.1 76.1 11.6 105.1 19.7 36.1 127.5 103.8 87.1 6.8 8.1 5.2 12.5 66.3 3.8 7.3 10.3 178.0 20.8 2.9 19.5 18.1 8.2 69.8 8.2 0.6 48.8 34.4 20.2 45.4 26.1 44.7 6.7 3.3 75.5 26.9 10.3 10.8 71.5 30.5 2.7 101.3 87.9 6.7 0.0 0.0 0.0 0.0 23.0 3.1 0.1 39.2 5.3 0.4 0.3 0.0 0.0 0.0 0.6 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.1 0.0 0.0 14.9 0.0 0.9 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.3 1.4 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.8 9.1 8.2 6.4 8.7 6.8 8.1 7.3 10.3 8.2 6.7 10.3 6.7 8.5 0.0 3.3 0.0 0.0 6.4 0.4 0.0 0.6 0.5 0.8 0.9 1.7 1.5 0.6 0.0 0.0 0.4 1.3 0.0 0.0 0.0 1.6 0.3 11.2 3.8 0.0 0.0 0.0 0.0 0.4 123.5 2.6 0.3 0.0 0.7 4.2 0.1 0.6 0.0 1.9 0.0 0.0 0.3 8.8 9.2 268.7 1.3 5.4 6.5 0.0 0.3 3.1 5.5 0.2 0.0 0.0 261.1 1.6 0.5 0.1 0.0 0.0 0.5 0.0 4.4 16.0 0.7 0.6 0.7 6.0 0.5 1.6 0.0 0.0 0.2 POLA2 FLJ21662 ENSG00000014138 "DNA polymerase alpha 2, accessory subunit" Q14181 11 65261920-65305589 "Metabolic proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.2;Spermatocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA037570 Supported Supported Nucleoplasm,Cytosol NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA037570: AB_10672280" "unprognostic (2.28e-1)" "prognostic favorable (4.61e-4)" "unprognostic (1.67e-2)" "unprognostic (7.44e-2)" "unprognostic (5.20e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (1.14e-1)" "unprognostic (2.87e-2)" "unprognostic (1.15e-2)" "unprognostic (4.05e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (4.09e-8)" "unprognostic (1.60e-3)" "unprognostic (8.26e-2)" "unprognostic (8.16e-2)" "unprognostic (6.25e-3)" 3.3 2.6 1.9 5.3 2.9 6.9 3.5 4.8 3.3 4.5 1.7 5.3 3.6 5.0 3.3 4.5 3.8 1.8 2.9 1.9 1.5 3.5 3.7 3.5 10.0 4.5 2.8 5.1 3.3 3.2 1.9 2.1 3.7 3.0 4.9 3.6 4.2 3.1 3.1 5.1 4.2 4.1 3.1 5.7 3.8 5.2 2.6 15.9 3.3 3.4 13.2 3.2 3.2 7.0 32.6 21.9 47.3 20.4 3.7 3.6 19.5 25.6 15.9 64.4 43.3 6.9 24.0 48.1 20.4 11.0 35.5 18.9 38.8 25.1 61.1 21.3 14.7 32.4 39.4 10.4 0.9 33.5 25.6 3.7 2.9 47.4 8.5 10.3 14.6 20.2 30.2 25.3 44.4 34.9 62.6 13.2 38.6 16.1 16.2 33.4 29.9 40.7 14.1 21.8 32.5 18.1 14.9 15.9 7.9 29.7 28.6 14.1 3.9 25.4 18.7 19.8 16.0 12.0 14.7 45.0 14.9 18.8 33.7 10.0 5.2 2.3 3.8 3.2 4.5 3.9 4.2 4.2 7.4 3.9 3.5 3.1 1.4 3.8 1.7 5.9 4.6 5.3 1.9 2.9 4.8 3.3 1.9 1.5 4.5 2.8 3.7 3.1 2.6 7.0 2.6 0.0 3.4 1.0 5.1 1.7 4.2 5.7 2.2 2.2 3.0 2.3 2.9 7.2 3.7 5.5 2.1 15.6 4.3 3.0 3.9 5.3 2.7 1.8 2.9 3.7 3.0 23.2 4.3 3.4 19.0 7.7 5.6 2.5 0.0 11.0 5.3 2.1 9.7 3.3 3.6 3.5 2.0 2.8 3.7 4.0 7.5 5.3 0.0 12.2 8.0 2.2 5.2 1.5 8.7 4.9 2.2 7.5 10.4 3.4 1.7 2.0 3.2 5.4 6.6 19.6 5.0 23.7 17.7 4.3 1.4 7.3 5.5 4.0 6.3 3.7 POLQ POLH ENSG00000051341 "DNA polymerase theta" O75417 3 121431427-121546641 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Excitatory neurons: 9.5;Granulosa cells: 12.6;Inhibitory neurons: 7.8;Plasma cells: 12.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.5" HPA053359 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Cytosol" "HPA053359: " "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (2.70e-1)" "unprognostic (6.23e-3)" "unprognostic (3.09e-5)" "unprognostic (8.55e-3)" "unprognostic (1.09e-4)" "unprognostic (2.86e-1)" "unprognostic (5.59e-5)" "unprognostic (2.06e-3)" "unprognostic (0.00e+0)" "prognostic favorable (1.04e-4)" "unprognostic (1.76e-1)" "unprognostic (6.01e-2)" "unprognostic (5.76e-2)" 0.1 0.2 0.0 1.6 0.1 6.0 0.4 1.0 0.2 0.2 0.0 1.2 1.2 0.2 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 2.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 2.0 0.0 0.3 0.0 0.0 1.4 0.9 0.4 0.0 0.8 0.5 2.2 0.0 4.5 0.0 0.0 2.3 0.3 0.5 0.0 18.2 12.1 10.2 7.2 0.9 1.2 9.2 8.5 3.2 9.7 12.9 9.8 6.6 21.5 3.7 4.6 11.7 14.0 12.2 5.4 16.4 6.3 6.7 13.8 8.0 6.1 0.1 15.1 12.1 0.2 0.4 8.9 5.4 1.7 4.9 7.9 9.3 15.9 10.3 7.1 13.7 8.8 9.7 5.5 5.9 11.4 12.2 7.6 3.1 10.3 5.5 5.0 9.8 5.2 3.4 8.8 4.8 14.8 3.8 8.6 11.2 3.4 11.1 8.0 6.9 21.8 4.1 11.0 6.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 1.6 0.7 0.9 0.5 0.6 0.0 0.9 0.6 0.6 1.6 0.0 2.0 0.0 0.0 3.1 0.6 1.6 0.0 0.1 0.4 0.9 1.0 0.5 0.0 16.4 9.5 0.0 3.3 1.2 4.6 1.0 0.0 12.6 0.0 0.2 2.3 0.0 7.8 1.6 2.0 1.3 1.2 0.7 0.3 1.7 0.0 1.0 0.6 0.4 0.0 1.5 1.3 0.2 1.2 0.0 12.2 0.5 0.2 0.1 2.4 0.2 0.0 0.1 1.0 6.8 3.4 4.9 0.1 0.3 1.8 0.9 3.2 0.8 POLR1D "AC19, MGC9850, RPA16, RPA9, RPAC2, RPO1-3" ENSG00000186184 "RNA polymerase I and III subunit D" "P0DPB5, P0DPB6" 13 27620742-27744237 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 819.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039337 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Golgi apparatus" "HPA039337: AB_10672961" "unprognostic (1.33e-3)" "unprognostic (5.96e-2)" "unprognostic (4.35e-2)" "unprognostic (8.50e-3)" "unprognostic (1.98e-2)" "unprognostic (3.71e-3)" "unprognostic (5.33e-3)" "unprognostic (2.04e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-2)" "unprognostic (2.80e-1)" "unprognostic (5.18e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (2.56e-2)" "unprognostic (8.28e-2)" "unprognostic (6.45e-2)" 72.1 124.8 56.0 57.4 58.5 150.8 90.6 77.5 75.5 102.5 67.2 98.7 86.2 67.5 78.1 142.3 75.7 55.8 90.7 58.4 57.3 84.4 81.2 76.5 90.8 53.4 54.7 118.7 267.3 54.2 69.3 62.3 54.9 88.6 87.4 58.5 112.5 65.7 119.9 143.4 86.6 66.4 52.7 75.6 132.9 76.0 55.3 117.5 62.2 85.0 87.3 91.7 111.7 56.3 103.2 94.8 106.8 110.5 121.6 213.4 143.4 99.2 171.2 129.2 127.7 155.0 203.9 331.3 73.2 113.9 215.7 155.4 200.4 319.8 152.3 102.5 119.0 236.0 97.4 262.9 181.4 215.7 178.0 195.5 330.2 106.0 194.6 143.9 180.9 187.9 132.3 56.6 126.8 106.7 213.2 257.7 259.1 320.2 100.4 144.0 182.6 151.1 204.7 157.2 182.2 142.3 67.3 132.0 381.4 133.9 81.3 198.6 124.9 56.5 90.1 97.9 110.3 92.2 113.1 188.4 49.5 152.3 112.9 80.0 115.9 56.3 71.0 124.4 94.5 83.9 114.9 91.8 130.9 83.8 121.8 98.4 42.0 88.8 113.5 95.9 179.0 83.8 56.0 58.5 77.5 75.5 58.4 57.3 53.4 54.7 54.9 52.7 55.3 56.3 122.5 89.8 108.8 13.7 147.4 336.6 303.0 247.7 385.3 56.6 171.4 241.4 73.5 118.7 123.8 29.5 16.7 155.0 133.9 104.5 74.3 137.2 464.1 100.9 98.4 111.8 124.4 182.4 30.0 309.2 273.2 100.5 126.4 106.3 95.7 125.8 112.5 81.2 165.7 45.4 22.2 203.5 65.1 205.2 148.2 819.5 116.5 142.5 80.0 19.7 260.9 56.5 151.4 13.6 22.3 232.1 124.6 79.0 105.9 256.2 210.1 152.1 58.5 44.0 78.9 105.2 164.4 268.0 81.9 307.8 317.0 145.8 148.5 179.8 197.2 345.7 POLR2F "HRBP14.4, RPB6" ENSG00000100142 "RNA polymerase II, I and III subunit F" P61218 22 37952607-38041915 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 4 "melanoma: 1.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000827, CAB009882" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "CAB009882: AB_2299942, HPA000827: AB_1079834" "unprognostic (8.27e-2)" "unprognostic (7.50e-2)" "unprognostic (1.51e-3)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (2.73e-3)" "unprognostic (2.85e-1)" "unprognostic (5.87e-2)" "unprognostic (4.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.11e-4)" "unprognostic (9.08e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-1)" "unprognostic (7.86e-2)" 52.5 61.1 73.4 34.6 92.3 38.9 50.8 77.5 90.2 59.5 56.9 64.9 37.7 53.2 24.8 58.7 50.2 19.5 91.8 74.2 91.2 58.2 118.6 41.6 31.0 87.9 83.9 60.9 47.5 76.5 62.7 30.2 82.6 47.7 28.7 16.8 56.1 39.6 111.0 45.8 42.3 28.8 75.3 36.4 57.6 48.8 86.8 36.7 54.7 68.4 26.3 53.1 52.7 123.7 150.7 176.2 120.6 128.7 141.1 81.7 109.4 138.0 81.0 141.4 130.5 210.0 51.8 117.4 99.1 120.3 138.3 106.4 166.9 135.7 67.1 143.0 303.7 107.3 181.3 289.1 125.9 213.6 67.0 112.4 99.8 186.3 72.1 71.2 118.7 130.4 208.9 93.7 101.9 220.2 168.4 258.2 174.3 175.4 134.7 162.3 110.4 134.5 77.4 94.8 180.6 67.2 129.5 88.9 215.3 69.6 62.9 144.3 110.5 119.8 173.9 150.4 158.1 106.0 178.0 247.9 122.4 107.9 138.4 118.9 92.9 140.8 83.8 90.4 78.5 95.8 71.9 81.8 86.3 71.3 63.1 63.7 122.8 113.7 78.5 123.3 103.4 85.3 73.4 92.3 77.5 90.2 74.2 91.2 87.9 83.9 82.6 75.3 86.8 123.7 82.6 38.5 85.9 9.4 73.2 204.3 113.9 205.4 63.7 26.7 133.8 168.7 0.3 101.5 122.5 121.4 25.0 243.5 70.5 148.7 193.7 160.0 117.0 96.0 117.2 94.8 117.2 109.6 9.9 159.5 303.4 97.4 58.1 82.4 90.0 90.0 98.6 304.4 178.5 28.6 10.7 143.1 116.0 94.2 102.9 42.0 159.7 65.9 225.9 2.8 102.3 99.4 111.2 9.5 99.0 182.4 152.9 151.2 65.7 137.3 196.6 306.5 114.3 33.3 157.8 90.1 197.1 237.0 241.0 106.0 224.3 211.9 82.4 82.7 145.7 121.2 POLR3B "C128, FLJ10388, RPC2" ENSG00000013503 "RNA polymerase III subunit B" Q9NW08 12 106357748-106510198 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 24.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036466 Supported Approved "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA036466: AB_10671842" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (4.80e-2)" "unprognostic (1.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-1)" "unprognostic (4.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.33e-1)" "unprognostic (3.36e-2)" "unprognostic (6.11e-2)" "unprognostic (5.09e-2)" "prognostic favorable (1.21e-4)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (8.73e-2)" "unprognostic (9.24e-2)" 4.5 8.7 3.1 4.8 4.4 5.2 5.0 4.3 4.6 4.7 3.7 5.3 4.2 4.6 5.2 8.6 5.1 3.6 5.8 3.4 2.9 6.8 9.0 4.7 4.1 2.2 2.3 7.5 4.9 11.1 2.4 6.7 2.3 5.6 5.7 6.2 4.7 4.0 6.5 11.0 3.4 5.4 2.7 3.3 5.4 6.1 3.2 4.7 6.0 8.3 5.6 4.9 4.3 3.6 16.2 7.6 16.4 7.8 13.9 13.1 22.9 21.9 13.0 15.2 11.6 14.0 4.4 20.6 7.7 14.2 5.6 14.8 19.5 19.2 18.5 16.6 13.1 15.7 10.1 12.0 9.2 26.1 17.0 11.7 13.4 15.1 17.3 10.3 11.5 9.8 24.5 6.5 11.2 12.0 19.1 8.7 17.8 11.9 28.5 11.6 9.8 13.5 8.6 21.8 17.3 9.6 13.6 18.2 13.4 10.8 17.0 7.9 11.0 8.3 10.0 13.6 13.1 8.1 22.4 30.3 3.8 15.9 9.2 5.6 2.0 1.5 2.0 2.2 2.7 2.1 2.2 2.2 2.6 1.3 3.0 1.9 1.3 2.1 2.2 0.9 2.7 1.7 3.1 4.4 4.3 4.6 3.4 2.9 2.2 2.3 2.3 2.7 3.2 3.6 2.4 0.0 9.2 14.4 4.7 1.8 1.7 4.5 4.6 6.0 3.4 3.7 10.3 2.8 7.0 5.5 6.2 11.0 3.8 3.8 1.9 5.1 7.1 3.9 7.0 3.3 4.2 3.8 22.3 4.6 9.3 4.4 9.2 3.9 5.1 4.8 3.6 11.0 3.1 3.3 24.1 5.6 2.0 1.6 0.3 5.2 3.7 2.4 3.6 9.4 1.0 2.4 2.1 17.1 22.4 3.8 1.1 4.9 4.9 1.5 1.7 3.4 7.2 7.2 6.6 6.9 4.1 16.5 10.9 8.9 3.0 7.4 4.1 7.2 5.1 1.2 PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359872-95396375 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 616.7" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 509.6" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 28.9;CACO-2: 8.6;CAPAN-2: 6.5;Hep G2: 32.6;T-47d: 17.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA014848, CAB025250" Enhanced "Secreted to blood" NA NA 1760000000 380000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" 1.4 3.8 2.1 0.5 2.0 0.0 31.2 1.7 1.9 5.3 1.4 2.0 7.9 0.9 3.6 0.5 1.3 4.4 1.0 1.8 2.1 2.7 616.7 14.2 0.1 2.3 2.2 12.4 14.3 0.2 24.9 0.8 2.9 0.9 2.8 0.1 26.3 3.9 0.3 7.4 3.1 0.2 2.1 0.3 2.3 9.0 2.1 1.6 7.1 0.3 5.9 1.4 0.9 1.9 3.1 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 6.5 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.1 17.4 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 1.7 1.9 1.8 2.1 2.3 2.2 2.9 2.1 2.1 1.9 2.5 6.4 45.9 24.5 0.6 0.9 0.9 9.3 1.8 0.0 5.4 4.3 0.5 31.5 23.9 3.7 0.0 1.7 0.3 3.2 1.9 0.3 14.5 0.0 0.4 1.9 0.0 8.0 0.1 2.0 2.2 5.2 0.5 0.0 0.0 0.4 10.0 509.6 0.2 0.0 0.2 1.8 12.2 8.1 0.3 4.8 8.1 0.2 14.2 4.7 0.0 3.2 0.0 17.6 0.1 1.2 1.2 3.0 0.0 2.1 6.0 6.7 6.5 0.1 0.0 0.8 2.1 21.4 16.9 0.3 1.3 1.4 0.8 6.6 2.3 0.4 POP7 "RPP2, RPP20" ENSG00000172336 "POP7 homolog, ribonuclease P/MRP subunit" O75817 7 100706121-100707486 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021007 Uncertain Supported Nucleoli,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli, Vesicles" "HPA021007: AB_10963575" "unprognostic (3.19e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.98e-2)" "unprognostic (2.28e-1)" "unprognostic (3.12e-2)" "unprognostic (9.50e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (6.21e-2)" "unprognostic (6.73e-2)" 25.6 31.7 30.1 18.1 31.6 33.9 26.6 33.4 38.6 24.2 23.8 27.9 19.3 27.7 11.0 34.0 21.3 9.8 37.6 32.3 30.8 25.8 67.1 18.2 17.3 30.1 27.8 18.1 31.3 16.6 22.8 16.6 30.8 22.6 9.2 9.6 29.0 13.5 69.0 50.2 22.3 12.1 29.4 22.7 26.4 12.5 29.1 15.6 16.8 31.9 12.0 25.4 24.9 33.9 115.7 115.3 47.2 78.4 25.1 23.9 92.0 65.6 32.4 73.7 73.1 159.8 71.0 97.5 105.1 30.0 81.4 70.4 70.1 79.5 36.8 82.7 212.4 44.9 75.0 166.5 42.1 69.2 49.8 27.6 30.2 76.2 74.8 20.9 41.6 68.9 157.4 77.8 39.8 330.4 158.0 232.9 135.2 77.8 164.4 123.6 50.0 159.4 45.3 65.2 90.4 92.3 54.5 156.2 78.7 42.0 50.0 66.2 41.3 92.0 117.7 191.0 127.6 34.0 99.4 175.8 61.0 115.1 104.6 106.3 63.2 72.4 54.7 64.7 50.7 60.3 54.6 54.3 55.3 47.7 49.5 52.0 39.0 78.9 70.3 51.2 69.8 62.5 30.1 31.6 33.4 38.6 32.3 30.8 30.1 27.8 30.8 29.4 29.1 33.9 30.5 19.2 17.0 2.9 29.7 105.0 32.0 57.2 56.3 26.1 61.6 64.1 27.9 37.1 31.5 35.0 6.2 148.2 25.8 51.8 93.9 75.4 2.1 31.2 32.3 37.2 40.2 50.1 5.2 87.4 181.3 37.3 25.0 35.1 17.7 32.4 33.5 99.0 66.1 32.0 6.0 61.7 67.1 27.3 40.7 7.9 42.0 22.4 56.9 2.8 38.7 41.8 41.2 4.0 5.8 92.2 47.6 37.2 55.1 75.6 69.8 86.1 27.8 21.3 46.0 29.8 52.2 9.2 45.5 74.7 119.2 139.3 27.2 39.9 55.8 43.5 POPDC2 POP2 ENSG00000121577 "Popeye domain containing 2" Q9HBU9 3 119636457-119665324 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 405.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 272.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 10 "SH-SY5Y: 24.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA024255 Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024255: AB_1855545" "unprognostic (1.13e-1)" "unprognostic (1.17e-3)" "unprognostic (8.91e-3)" "unprognostic (9.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.64e-2)" "unprognostic (2.73e-2)" "unprognostic (2.43e-1)" "unprognostic (3.18e-2)" "unprognostic (1.72e-2)" "unprognostic (5.86e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-2)" "unprognostic (6.26e-3)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-2)" 3.6 2.1 0.6 3.8 0.5 0.3 3.3 0.8 0.9 7.9 1.3 95.3 2.8 12.5 2.6 2.0 9.6 10.9 405.4 0.5 0.5 2.4 1.0 2.5 6.7 0.6 0.6 2.0 1.3 8.4 1.3 1.4 0.6 16.3 6.2 0.9 3.3 49.2 77.7 2.8 12.2 24.0 0.5 2.8 10.7 1.0 0.6 1.5 2.4 96.9 2.5 35.3 6.0 0.5 0.1 0.2 0.5 0.0 0.2 0.2 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.0 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.2 0.0 0.3 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.2 24.8 0.0 0.0 0.6 2.5 0.0 0.3 0.0 0.2 0.1 0.2 0.1 1.0 0.0 0.2 0.2 0.3 0.5 0.5 0.0 0.7 0.3 0.0 0.4 0.1 0.5 0.4 0.0 0.4 0.8 0.2 0.0 0.2 1.3 0.2 0.7 0.1 0.6 0.5 0.8 0.9 0.5 0.5 0.6 0.6 0.6 0.5 0.6 0.5 4.7 0.0 0.5 1.0 0.6 0.4 0.3 0.5 0.0 3.1 0.9 3.0 272.7 0.0 0.9 0.0 0.0 0.5 2.3 0.4 0.0 0.5 0.3 0.6 0.5 6.4 3.0 0.0 0.8 0.2 0.1 8.0 0.5 0.3 1.3 1.6 1.4 0.2 1.6 1.7 1.2 0.8 0.0 1.0 2.3 0.8 1.2 1.6 0.0 2.8 1.8 1.2 0.0 1.0 1.9 0.5 0.2 1.9 0.0 0.8 0.7 0.3 1.9 2.4 59.2 5.9 11.1 1.0 0.3 0.1 0.6 1.2 1.6 0.6 0.3 0.2 POU2F3 "Epoc-1, OCT11, PLA-1, Skn-1a" ENSG00000137709 "POU class 2 homeobox 3" Q9UKI9 11 120236640-120319945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 48.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.9;Pancreatic endocrine cells: 20.8;Suprabasal keratinocytes: 37.6;Urothelial cells: 14.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.4;CAPAN-2: 3.6;EFO-21: 1.3;SK-BR-3: 2.5;T-47d: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019652, HPA073468" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Nucleoli, Nuclear bodies, Plasma membrane, Cytosol" "HPA019652: AB_1855585, HPA073468: " "unprognostic (1.75e-1)" "unprognostic (2.12e-2)" "unprognostic (6.37e-2)" "unprognostic (2.41e-4)" "unprognostic (2.60e-1)" "unprognostic (4.46e-3)" "unprognostic (8.56e-3)" "unprognostic (9.34e-2)" "unprognostic (3.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-3)" "unprognostic (2.08e-1)" "unprognostic (1.27e-2)" "unprognostic (9.69e-3)" "unprognostic (1.70e-1)" "prognostic favorable (8.14e-4)" "unprognostic (1.45e-1)" 0.1 0.1 0.2 0.1 0.1 0.2 2.0 0.3 0.4 0.8 0.0 0.6 0.9 0.0 1.7 1.3 0.5 0.7 0.1 0.1 0.1 0.3 0.1 1.0 0.2 0.1 0.1 0.1 0.2 6.3 0.4 0.3 0.1 0.6 0.2 0.1 1.1 2.0 0.2 48.0 0.7 0.3 0.0 0.2 0.7 0.1 0.1 0.2 0.7 0.0 0.5 0.4 2.1 0.3 1.4 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.3 0.0 0.0 0.0 3.6 0.1 1.3 0.0 0.0 0.6 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 2.5 0.0 0.3 3.9 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 8.2 0.3 0.0 20.9 10.6 5.0 1.8 0.0 3.0 1.5 0.8 0.0 3.9 11.0 0.0 1.5 0.1 0.9 0.0 5.3 2.2 1.3 0.7 0.3 3.0 0.0 0.4 1.3 0.4 0.6 10.2 4.8 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.2 8.2 0.0 2.2 5.5 0.0 0.1 5.4 0.0 0.0 0.4 0.0 0.0 0.5 20.8 1.1 0.0 0.0 5.0 0.4 0.1 1.8 0.0 0.0 0.0 0.4 0.0 0.1 7.0 37.6 7.9 0.5 0.2 0.6 14.2 POU3F1 "OCT6, OTF6, SCIP" ENSG00000185668 "POU class 3 homeobox 1" Q03052 1 38043829-38046793 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 10.3;skin 1: 32.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 27.3;Breast myoepithelial cells: 39.1;Cone photoreceptor cells: 22.9;Suprabasal keratinocytes: 55.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.8;head and neck cancer: 4.4;melanoma: 4.8;testis cancer: 1.3;urothelial cancer: 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 24.1;HDLM-2: 23.9;NTERA-2: 7.5;SCLC-21H: 5.7;SK-MEL-30: 28.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055980, HPA073824" Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA055980: AB_2682995, HPA073824: AB_2686635" "unprognostic (9.99e-2)" "unprognostic (1.63e-1)" "unprognostic (1.69e-1)" "unprognostic (1.43e-2)" "unprognostic (7.46e-3)" "unprognostic (1.96e-2)" "unprognostic (1.33e-2)" "unprognostic (2.56e-1)" "unprognostic (1.11e-1)" "unprognostic (3.07e-2)" "unprognostic (4.40e-2)" "unprognostic (1.40e-1)" "unprognostic (4.61e-4)" "unprognostic (2.79e-2)" "unprognostic (1.97e-1)" "unprognostic (3.61e-2)" "unprognostic (2.67e-3)" 0.2 1.5 2.3 0.2 7.0 0.0 0.3 0.9 10.3 0.2 0.1 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.1 9.7 1.9 0.0 0.0 0.0 1.0 1.4 2.6 0.1 0.1 0.2 0.0 0.0 1.3 0.2 0.0 0.3 0.3 0.1 0.9 32.6 0.0 0.0 0.6 0.1 0.1 0.8 2.0 0.3 0.0 0.5 1.0 0.8 0.3 2.5 0.0 0.0 24.1 0.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 23.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.0 1.4 5.7 0.0 0.1 0.0 28.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 7.0 0.9 10.3 9.7 1.9 1.4 2.6 1.3 0.6 2.0 2.5 12.2 0.0 0.0 2.3 8.3 27.3 2.9 1.4 20.5 7.8 9.9 39.1 5.2 0.0 0.2 0.0 22.9 0.2 13.4 13.8 0.0 0.0 0.2 0.5 2.3 1.9 1.8 2.7 6.4 0.0 0.1 5.2 7.1 1.4 0.0 0.5 0.0 0.0 0.3 1.7 1.1 11.0 0.0 0.0 1.3 0.0 0.3 4.3 7.2 1.0 0.0 14.0 0.0 0.5 0.2 0.0 0.1 0.0 2.7 0.7 0.3 0.1 0.0 21.1 0.0 8.5 7.2 0.2 4.1 20.2 55.8 0.1 5.2 8.3 5.7 3.2 PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243756 "FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 44.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 99.4;Hepatocytes: 144.5;Proximal enterocytes: 93.2;Rod photoreceptor cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 10.3;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 5 "dendritic cells: 3.1;granulocytes: 10.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058901, HPA067049, CAB075701" Supported Enhanced Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB075701: , HPA058901: AB_2683849, HPA067049: AB_2685770" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (3.94e-3)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (2.95e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" "unprognostic (1.01e-1)" "prognostic favorable (4.39e-9)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" 7.9 6.3 9.6 4.5 12.7 6.6 3.8 9.5 6.9 4.1 23.5 11.8 18.4 3.8 3.6 7.7 4.1 4.4 26.3 7.7 8.8 22.4 33.2 4.0 3.4 11.0 11.2 11.2 8.2 7.4 2.6 4.3 10.0 6.2 9.1 18.2 7.8 5.7 26.2 7.7 18.4 4.3 8.6 4.4 6.1 1.3 11.7 3.7 7.0 44.6 3.9 5.1 4.0 10.5 7.8 1.9 2.4 8.4 13.0 8.3 5.3 6.7 13.2 7.0 7.2 3.8 3.7 2.8 3.3 15.6 6.5 3.5 7.1 8.7 6.3 8.1 8.9 8.7 4.8 8.0 8.1 6.0 14.3 6.6 6.9 5.2 11.8 6.0 1.5 6.3 3.2 6.4 6.6 2.0 6.8 2.2 0.3 6.5 1.9 8.0 8.6 3.6 4.7 4.6 2.4 7.0 2.6 2.4 8.0 3.2 2.7 4.6 2.6 7.3 7.7 6.7 2.9 6.3 4.0 1.2 11.4 6.6 2.3 1.4 0.8 10.3 1.0 1.0 0.8 0.8 0.5 0.5 0.6 1.0 0.6 0.4 0.7 0.7 0.7 3.1 1.4 0.2 9.6 12.7 9.5 6.9 7.7 8.8 11.0 11.2 10.0 8.6 11.7 10.5 15.0 3.2 13.6 49.6 8.0 23.3 15.0 7.8 9.1 15.0 14.3 11.4 99.4 22.8 8.9 7.3 62.6 8.0 18.4 58.8 9.8 10.3 0.6 9.4 26.4 15.5 19.9 32.0 1.4 16.6 6.7 16.0 14.8 18.4 5.1 19.1 22.5 144.5 8.8 5.0 13.8 31.4 0.0 24.8 10.2 1.1 19.6 10.4 3.6 10.3 12.2 16.0 8.2 19.6 27.2 13.0 24.5 30.1 10.6 19.1 93.2 40.8 5.0 148.0 6.6 31.0 15.8 0.7 1.7 19.3 34.2 3.0 9.6 14.6 37.9 19.9 PPARGC1A "PGC-1alpha, PGC1, PGC1A, PPARGC1" ENSG00000109819 "PPARG coactivator 1 alpha" Q9UBK2 4 23755041-23904089 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Activator, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.6" "Group enriched" "Detected in many" 5 "Excitatory neurons: 1098.2;Inhibitory neurons: 1704.4;Oligodendrocyte precursor cells: 890.2" "Cancer enhanced" "Detected in many" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "A-431: 88.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063136 Supported Nucleoplasm NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA063136: AB_2684948" "unprognostic (1.08e-1)" "unprognostic (7.47e-2)" "unprognostic (6.85e-3)" "unprognostic (2.28e-6)" "unprognostic (5.00e-2)" "unprognostic (1.15e-1)" "prognostic favorable (3.35e-6)" "unprognostic (3.04e-1)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (6.77e-2)" "unprognostic (4.58e-2)" "prognostic favorable (1.49e-14)" "unprognostic (3.62e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.07e-3)" 2.3 2.9 4.2 0.6 3.2 0.0 1.6 7.6 13.0 3.3 33.9 7.4 7.6 0.9 1.5 3.3 1.5 2.6 36.3 3.1 10.7 29.0 44.6 3.1 0.2 4.1 4.1 1.2 3.8 38.5 4.8 0.1 2.6 3.3 9.1 4.2 29.3 3.0 29.5 8.2 6.6 1.9 2.4 0.8 4.3 4.5 7.2 2.3 17.7 37.2 0.4 1.1 1.0 4.1 88.6 0.0 1.6 0.0 2.6 0.0 0.0 0.0 1.9 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.8 0.0 4.5 10.7 0.0 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.4 7.6 0.0 0.0 0.7 0.0 12.3 0.1 4.0 0.2 2.8 0.0 3.5 4.2 0.5 1.4 0.0 0.7 0.7 0.0 1.6 8.1 0.1 0.1 1.6 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.2 7.6 13.0 3.1 10.7 4.1 4.1 2.6 2.4 7.2 4.1 2.5 19.2 2.6 240.6 0.9 0.9 4.1 7.4 1.2 7.0 2.7 1.5 90.9 47.1 6.3 36.8 39.6 0.0 0.0 36.0 52.8 12.0 78.3 7.2 1.3 0.8 26.7 0.0 1098.2 0.0 0.0 2.4 4.1 9.7 1.3 0.2 1.1 88.8 0.0 0.0 1704.4 17.0 38.7 2.5 0.3 69.7 0.9 0.6 7.2 24.4 0.1 6.4 0.0 890.2 28.8 0.6 7.3 2.2 1.8 1.4 32.0 26.8 4.8 1.9 0.0 37.1 5.1 0.8 0.6 2.6 1.1 0.0 1.0 1.9 21.9 1.5 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036725 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 251.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 229.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" NA NA 3700000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA039163: AB_2676374" "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 37.0 20.6 5.3 16.4 5.6 0.2 30.4 6.8 7.0 42.3 12.2 41.4 37.3 31.0 36.5 46.8 14.8 33.5 44.4 5.2 5.8 24.9 28.9 27.0 7.6 6.4 6.3 16.2 30.3 20.9 6.2 48.3 6.2 23.4 49.9 4.9 31.7 24.0 41.2 20.2 32.3 45.2 6.1 7.7 22.4 9.0 6.7 5.8 47.2 33.3 14.2 45.8 28.8 5.8 19.6 16.8 6.4 136.2 229.7 104.6 26.9 54.4 42.3 27.8 56.7 28.1 128.6 0.0 94.2 147.1 83.3 21.9 18.9 68.6 22.1 0.1 33.1 27.8 60.7 32.8 58.9 0.0 14.7 65.8 51.5 32.5 34.0 49.9 58.1 0.0 7.9 0.0 20.1 116.5 0.1 0.3 11.6 120.9 29.0 0.0 14.5 0.0 87.7 67.0 8.5 14.9 106.7 51.1 12.1 77.8 72.0 61.8 64.8 52.9 32.7 18.5 23.9 0.2 0.1 0.4 45.9 0.2 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.6 6.8 7.0 5.2 5.8 6.4 6.3 6.2 6.1 6.7 5.8 214.1 32.1 16.5 6.2 1.6 47.4 52.3 251.7 30.7 16.9 63.9 47.5 46.4 61.5 149.0 73.5 4.2 60.1 0.6 134.0 29.4 201.5 1.7 52.4 94.8 106.5 12.7 0.0 0.8 126.4 65.2 198.2 55.0 50.8 1.3 54.2 80.7 57.8 43.2 0.0 2.2 177.1 207.5 4.2 40.3 4.2 112.5 6.9 32.0 5.6 3.2 2.8 0.0 1.0 0.3 90.3 181.0 100.1 0.6 48.2 189.0 81.7 110.5 4.4 39.5 22.7 87.5 41.6 37.8 118.6 49.3 25.0 3.4 61.2 117.0 81.5 PPIF "Cyp-D, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355334 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Necrosis" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 370.9;Macrophages: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 75.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 320000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" 62.7 227.7 42.7 42.8 48.4 168.8 42.4 57.9 69.6 27.6 63.7 50.0 36.3 14.0 7.2 66.0 22.9 19.5 119.1 38.1 45.2 63.3 174.9 29.1 32.3 49.0 56.2 19.3 86.9 77.6 18.3 27.1 48.8 18.8 52.4 8.9 39.5 45.5 99.5 71.9 31.3 21.0 50.6 58.7 98.2 35.0 57.1 28.3 26.0 133.6 55.5 60.0 35.1 60.8 220.4 90.6 62.3 123.5 57.0 73.6 79.8 124.2 161.2 265.7 249.6 213.5 102.7 224.8 68.0 87.4 188.6 127.8 195.3 115.4 410.5 72.2 186.4 352.8 87.5 380.7 96.4 245.7 80.4 173.2 81.3 264.5 262.3 86.5 47.5 86.4 351.6 268.3 91.6 111.7 64.1 204.2 53.0 99.6 500.6 109.8 96.4 114.7 103.9 200.0 124.1 92.0 63.6 253.8 97.9 40.5 111.4 187.2 43.5 116.1 106.3 137.9 242.0 124.7 137.7 181.9 114.5 313.9 32.0 15.2 34.3 18.0 10.4 27.5 10.9 19.1 9.1 9.6 43.3 7.7 8.1 7.9 75.0 9.0 10.4 5.4 10.0 16.6 42.7 48.4 57.9 69.6 38.1 45.2 49.0 56.2 48.8 50.6 57.1 60.8 8.4 6.4 6.8 7.2 32.7 42.6 30.2 23.8 31.3 4.0 41.8 40.8 124.6 14.3 14.4 12.9 6.2 99.4 26.4 39.9 92.0 42.1 14.5 12.4 24.0 10.1 21.6 37.0 4.1 28.0 127.1 25.1 78.0 15.5 13.4 73.4 6.1 98.5 91.1 8.4 5.7 69.5 18.3 40.3 370.9 14.1 6.2 160.8 35.6 4.7 32.0 13.0 5.2 5.5 15.0 39.8 26.6 6.0 48.7 41.4 21.3 41.2 12.6 5.2 19.7 18.2 28.6 14.8 22.5 52.9 37.6 142.3 23.9 60.2 81.1 34.2 PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715477 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 18.8;skeletal muscle: 68.4;skin 1: 18.1;testis: 63.8;tongue: 25.6" "Group enriched" "Detected in many" 4 "Early spermatids: 123.6;Late spermatids: 281.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 67.9" "Lineage enriched" "Detected in many" 15 "dendritic cells: 67.9" "Cell line enhanced" "Detected in many" "T-47d: 19.5" "Region enriched" "Detected in many" 7 "olfactory bulb: 27.3" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA046045: AB_2679516" "unprognostic (8.68e-2)" "unprognostic (5.65e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.93e-3)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-2)" "unprognostic (2.55e-1)" "unprognostic (9.30e-3)" "unprognostic (3.36e-2)" "unprognostic (7.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.28e-2)" "unprognostic (9.96e-4)" 1.1 2.6 6.3 1.0 6.6 0.7 2.2 5.9 6.5 2.3 3.8 1.2 0.6 1.9 18.8 4.6 2.8 1.0 8.7 5.8 5.7 7.8 0.7 1.6 3.3 5.2 7.8 2.3 1.7 5.5 2.6 0.5 4.6 3.3 0.6 6.9 2.8 2.1 68.4 18.1 1.4 1.3 4.5 1.4 1.2 63.8 9.1 2.3 3.1 25.6 2.2 1.1 4.0 3.9 2.7 0.1 1.5 1.7 0.8 1.5 1.1 0.3 0.7 0.3 1.0 1.2 0.8 0.4 0.4 0.8 0.8 4.9 1.1 4.6 0.4 0.0 2.6 0.8 0.2 0.2 0.9 0.0 0.2 1.7 3.0 0.9 4.6 1.0 2.1 0.2 1.0 0.0 1.2 2.9 0.0 0.0 1.6 1.4 2.3 0.1 0.1 0.0 2.7 0.1 0.8 0.2 0.6 4.3 1.3 2.2 19.5 0.0 1.1 0.3 2.8 0.0 0.2 0.1 0.0 0.0 2.3 0.6 2.6 0.0 0.3 0.0 0.0 1.5 0.1 0.7 0.0 0.1 7.1 0.7 0.0 0.0 0.0 0.0 4.3 67.9 0.0 0.8 6.3 6.6 5.9 6.5 5.8 5.7 5.2 7.8 4.6 4.5 9.1 3.9 1.2 0.0 0.5 0.3 2.0 2.2 4.7 8.7 10.2 5.7 4.2 4.6 5.8 0.0 2.7 1.8 10.4 1.0 41.3 0.7 9.8 3.2 123.6 3.2 0.3 1.5 0.0 0.0 1.8 4.3 1.4 1.1 1.1 0.6 0.0 5.6 0.7 0.1 0.7 0.0 1.5 0.9 2.0 1.3 11.5 281.6 3.1 2.0 0.0 0.0 1.6 25.4 0.0 0.0 0.2 2.1 2.4 2.6 0.0 6.7 0.3 0.6 1.8 9.1 6.6 1.1 2.8 2.8 16.9 3.5 2.8 0.5 0.9 3.2 0.8 2.9 PPP1R11 "CFAP255, HCG-V, HCGV, TCTE5, Tctex5" ENSG00000204619 "Protein phosphatase 1 regulatory inhibitor subunit 11" O60927 6 30066709-30070333 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 696.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 8 "cerebral cortex: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 51.5;AN3-CA: 65.6;fHDF/TERT166: 48.6;GAMG: 47.4;HBEC3-KT: 53.6;JURKAT: 76.7;RPTEC TERT1: 47.4;U-266/84: 64.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043266, HPA060174" Approved Approved Vesicles NA NA 43000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA043266: AB_2678400, HPA060174: AB_2684216" "unprognostic (2.00e-2)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (4.24e-2)" "unprognostic (3.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (1.18e-1)" "unprognostic (2.81e-1)" "unprognostic (1.74e-3)" "unprognostic (3.33e-2)" "unprognostic (2.68e-1)" "unprognostic (8.36e-3)" "unprognostic (1.74e-1)" "unprognostic (3.31e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-3)" 44.5 41.1 0.7 0.0 0.7 1.9 41.4 0.6 8.8 44.4 0.6 55.5 11.6 49.6 33.1 52.1 37.3 11.8 51.0 0.7 0.7 62.3 47.5 43.7 5.4 0.9 0.7 41.8 45.1 2.2 29.2 5.8 0.8 46.3 0.7 7.9 42.8 0.0 50.4 42.9 50.7 0.0 0.6 39.8 59.5 41.5 0.7 9.7 42.3 0.0 11.8 51.6 42.7 1.1 51.5 0.0 0.0 65.6 29.4 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 48.6 47.4 0.0 0.0 53.6 0.0 1.0 34.5 42.6 0.0 0.0 0.0 3.0 3.9 0.0 0.0 0.0 0.7 0.0 0.0 76.7 0.5 2.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.4 47.4 29.0 0.0 0.0 0.7 35.5 4.8 26.8 0.0 0.0 0.0 0.0 0.3 4.1 1.5 30.7 64.9 26.7 0.7 0.0 0.0 11.5 4.1 12.4 4.7 9.3 4.5 6.8 5.3 6.5 2.2 7.2 4.9 7.0 2.8 3.9 7.9 3.2 8.4 6.8 0.7 0.7 0.6 8.8 0.7 0.7 0.9 0.7 0.8 0.6 0.7 1.1 38.2 19.2 20.2 2.6 57.8 52.8 80.0 77.2 29.0 29.3 47.7 32.8 18.8 52.9 49.7 40.5 6.2 56.0 39.2 111.5 95.9 142.2 242.1 19.8 24.2 44.3 53.7 32.4 10.1 136.3 119.9 27.0 53.5 31.8 78.6 21.4 45.7 28.0 65.7 13.5 9.0 83.8 77.3 49.7 53.8 696.0 32.3 43.5 62.2 3.7 75.4 58.4 92.7 6.0 7.6 136.5 114.1 40.3 42.2 66.6 139.6 93.3 38.7 33.1 39.5 27.2 89.4 61.9 23.2 39.0 66.5 75.2 52.4 16.5 51.8 94.9 PPP1R13L "IASPP, RAI" ENSG00000104881 "Protein phosphatase 1 regulatory subunit 13 like" Q8WUF5 19 45379638-45406349 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 179.4;heart muscle: 139.4;skin 1: 219.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.6;Granulosa cells: 118.3;Syncytiotrophoblasts: 128.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBEC3-KT: 130.1;hTCEpi: 189.0;hTERT-HME1: 131.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005016, HPA041231, HPA059883" Approved Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB005016: AB_2168576, HPA041231: AB_2677376, HPA059883: AB_2684151" "unprognostic (1.87e-1)" "unprognostic (1.78e-1)" "unprognostic (7.46e-2)" "unprognostic (2.92e-1)" "unprognostic (3.74e-1)" "unprognostic (2.06e-2)" "unprognostic (1.31e-3)" "prognostic unfavorable (3.39e-5)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.40e-4)" "unprognostic (2.52e-3)" "unprognostic (1.92e-2)" "unprognostic (1.55e-3)" "unprognostic (1.34e-1)" "unprognostic (7.69e-2)" "unprognostic (8.87e-2)" "unprognostic (1.02e-1)" 20.4 20.1 11.7 2.9 11.7 0.6 29.6 11.5 14.0 44.9 9.5 11.1 5.0 8.2 15.2 179.4 9.6 6.0 139.4 10.8 14.3 24.8 12.6 20.3 2.6 11.9 11.1 8.8 31.5 12.2 11.8 26.6 11.7 30.8 6.8 13.6 55.6 13.3 5.8 219.8 9.1 5.4 10.0 6.4 12.0 3.1 12.7 4.0 17.7 4.4 18.8 23.6 84.9 12.4 72.3 10.7 4.6 3.8 4.7 2.9 61.5 14.5 2.5 17.5 24.3 23.1 70.6 9.5 5.9 11.9 36.5 97.2 4.0 130.1 16.0 24.0 5.9 1.4 36.3 8.7 10.0 1.0 3.4 4.0 189.0 27.9 131.9 79.2 33.2 7.9 8.1 3.6 1.2 64.7 1.8 1.9 5.3 36.9 18.3 7.4 5.6 1.7 22.9 95.0 2.4 7.6 64.5 68.4 1.6 30.0 58.2 1.9 46.3 23.1 60.9 1.8 76.2 35.1 42.1 6.5 3.3 2.9 5.6 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.2 0.0 11.7 11.7 11.5 14.0 10.8 14.3 11.9 11.1 11.7 10.0 12.7 12.4 14.3 35.3 13.0 9.4 2.0 68.7 85.6 38.4 67.2 1.7 21.9 28.6 38.8 20.0 27.8 20.2 10.4 83.2 2.5 17.8 5.9 34.9 0.7 8.7 3.0 13.4 7.2 10.1 0.8 15.8 37.7 5.6 8.6 17.1 4.5 118.3 11.7 2.5 7.6 0.0 0.9 6.9 14.2 1.6 5.0 0.5 5.9 2.2 12.4 9.4 1.9 2.4 2.1 2.5 1.6 50.4 17.2 12.4 6.1 44.2 22.6 3.9 16.3 26.8 6.6 8.4 14.1 2.7 2.1 81.2 71.0 128.5 2.5 2.8 9.0 63.4 PPP1R14C "CPI17-like, KEPI, NY-BR-81" ENSG00000198729 "Protein phosphatase 1 regulatory inhibitor subunit 14C" Q8TAE6 6 150143044-150250392 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 75.5;skeletal muscle: 66.5;skin 1: 97.2;thyroid gland: 58.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 280.2;Cardiomyocytes: 79.5;Skeletal myocytes: 80.9;Suprabasal keratinocytes: 336.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 53.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 40.7;HBEC3-KT: 86.1;HEK 293: 36.2;hTCEpi: 103.0;hTERT-HME1: 41.1;RPTEC TERT1: 35.5;SK-BR-3: 37.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044667, HPA047907" Approved NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "CAB044667: , HPA047907: " "unprognostic (1.81e-3)" "unprognostic (7.65e-2)" "unprognostic (4.25e-3)" "unprognostic (6.92e-2)" "unprognostic (3.96e-3)" "unprognostic (2.20e-2)" "unprognostic (3.81e-3)" "unprognostic (1.55e-1)" "unprognostic (6.63e-2)" "unprognostic (5.13e-2)" "unprognostic (4.50e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.98e-1)" "unprognostic (7.49e-3)" "unprognostic (6.77e-2)" 0.4 0.2 5.1 1.4 6.6 0.2 6.0 5.9 8.0 10.2 6.0 12.5 10.4 1.4 0.9 18.4 16.0 0.1 75.5 7.8 5.0 9.5 0.0 12.3 0.3 5.6 5.4 0.1 0.7 5.1 1.7 3.4 5.6 1.3 8.6 0.6 3.2 0.2 66.5 97.2 2.7 0.9 4.4 0.1 0.8 6.7 5.0 0.5 58.7 8.5 5.8 0.5 22.0 5.0 27.9 0.1 11.7 0.1 0.1 0.6 0.0 3.7 0.0 0.0 0.1 1.3 3.8 0.7 8.0 5.3 1.8 40.7 6.1 86.1 0.0 0.0 36.2 0.3 0.0 0.0 0.0 0.0 1.1 0.0 103.0 0.2 41.1 0.0 0.0 0.5 23.6 0.0 0.0 3.8 0.0 0.0 0.4 0.0 0.2 0.7 0.0 0.0 35.5 1.5 6.2 0.0 0.6 37.7 2.2 0.7 0.2 1.9 0.0 0.1 20.4 32.5 9.5 0.0 0.0 0.0 14.2 16.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 6.6 5.9 8.0 7.8 5.0 5.6 5.4 5.6 4.4 5.0 5.0 0.3 19.2 41.1 1.3 0.5 280.2 17.9 19.6 12.0 1.1 6.5 4.3 79.5 0.0 17.1 14.7 0.0 0.1 0.4 24.5 1.9 3.8 0.2 37.9 0.6 3.0 28.2 0.0 28.0 0.2 0.1 6.7 0.0 5.1 1.3 4.1 0.0 0.0 3.0 1.7 13.3 3.1 14.2 0.0 19.7 1.6 0.0 0.6 30.2 2.8 1.1 0.0 0.0 37.2 2.5 12.8 41.5 0.4 0.0 16.6 5.0 38.6 61.5 0.5 0.0 80.9 4.3 0.5 1.8 14.7 336.6 1.9 1.4 0.5 8.7 1.9 PPP1R1A ENSG00000135447 "Protein phosphatase 1 regulatory inhibitor subunit 1A" Q13522 12 54575387-54588659 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 259.7;skeletal muscle: 831.6;tongue: 271.1" "Cell type enriched" "Detected in many" 4 "Distal tubular cells: 1348.0" "Cancer enhanced" "Detected in many" "liver cancer: 17.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 8.8;NTERA-2: 29.4;RPTEC TERT1: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007811, HPA041542" Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "CAB007811: AB_598171, HPA041542: AB_2677542" "unprognostic (6.39e-3)" "unprognostic (2.61e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (2.36e-5)" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.19e-3)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (7.04e-2)" "unprognostic (2.71e-3)" "unprognostic (1.76e-3)" "unprognostic (2.88e-3)" "unprognostic (7.68e-3)" "unprognostic (2.17e-1)" "unprognostic (8.49e-3)" "unprognostic (7.49e-2)" 241.3 2.6 37.1 1.1 73.6 0.3 169.8 26.1 45.7 1.6 20.4 29.6 3.0 2.2 0.7 10.3 3.8 1.5 110.9 38.9 36.9 259.7 138.1 1.0 0.5 29.0 32.0 7.7 14.2 20.8 1.8 0.0 26.0 7.9 1.8 14.6 9.7 3.2 831.6 7.6 13.2 3.3 25.5 0.5 27.8 2.2 31.6 0.2 2.6 271.1 0.5 5.4 1.5 34.1 0.0 0.0 3.9 0.0 8.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 5.4 0.0 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 0.0 0.2 32.6 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.3 0.0 0.0 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 73.6 26.1 45.7 38.9 36.9 29.0 32.0 26.0 25.5 31.6 34.1 7.9 0.0 0.0 3.3 3.4 0.1 0.0 0.0 0.0 2.2 23.7 40.6 300.7 5.7 0.0 18.4 0.0 0.0 0.5 0.0 1348.0 3.5 1.6 10.4 0.5 4.6 2.4 2.7 3.1 0.4 0.1 24.5 0.0 13.8 0.0 21.0 6.4 218.4 0.6 112.7 1.8 2.1 0.0 3.8 0.0 1.9 1.2 1.6 0.0 0.0 0.0 3.7 0.0 0.0 0.5 2.5 0.1 1.2 0.0 0.3 0.5 156.8 0.0 2.8 0.0 19.2 21.6 0.2 5.9 0.0 0.3 0.0 0.9 4.2 2.0 0.2 PPP1R1B "DARPP-32, FLJ20940" ENSG00000131771 "Protein phosphatase 1 regulatory inhibitor subunit 1B" Q9UD71 17 39626740-39636626 "Metabolic proteins, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 711.8;choroid plexus: 506.6;intestine: 211.4;salivary gland: 366.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 144.6;Distal tubular cells: 121.3;Intestinal goblet cells: 305.7;Melanocytes: 135.2;Paneth cells: 132.3;Undifferentiated cells: 423.7;Urothelial cells: 171.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 94.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "eosinophil: 1.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.0" "Cell line enhanced" "Detected in some" "ASC diff: 7.6;CAPAN-2: 12.6;HSkMC: 31.7;OE19: 15.6;SCLC-21H: 27.4" "Region enriched" "Detected in all" 8 "basal ganglia: 1243.8" "Region enriched" "Detected in all" 26 "basal ganglia: 1534.8" "CAB004026, HPA048630, HPA061142" Approved Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB004026: AB_2169007, HPA048630: AB_2680468, HPA061142: AB_2684438" "unprognostic (2.71e-1)" "unprognostic (4.09e-2)" "unprognostic (6.91e-3)" "unprognostic (2.42e-1)" "unprognostic (3.01e-1)" "unprognostic (7.69e-2)" "unprognostic (6.00e-3)" "unprognostic (2.76e-2)" "unprognostic (1.75e-2)" "unprognostic (6.13e-2)" "unprognostic (6.07e-2)" "unprognostic (2.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.52e-3)" "unprognostic (1.55e-1)" 93.8 30.2 280.9 19.8 711.8 0.4 74.0 262.7 312.7 20.0 506.6 211.4 83.4 4.4 5.5 4.8 28.4 2.0 3.5 251.7 244.0 29.1 0.5 15.3 0.1 319.6 275.5 11.3 75.7 0.5 15.0 0.0 232.4 62.7 203.4 6.2 366.9 89.7 0.9 56.3 68.7 10.8 243.3 0.1 39.9 15.8 317.9 0.2 0.6 0.0 0.3 18.9 11.4 249.6 0.0 0.0 0.0 0.0 7.6 4.4 0.2 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.9 15.6 0.9 0.0 0.0 0.6 0.0 0.0 27.4 0.6 0.0 1.5 0.0 2.4 0.6 1.1 0.0 0.0 1.8 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 280.9 711.8 262.7 312.7 251.7 244.0 319.6 275.5 232.4 243.3 317.9 249.6 1.0 0.0 34.7 33.3 1.3 1.3 117.1 0.4 0.6 0.6 93.5 84.3 1.1 0.0 0.2 1.8 0.0 0.0 2.4 144.6 121.3 28.7 0.8 46.6 0.9 1.6 96.7 0.0 5.3 3.3 0.0 2.8 13.3 3.2 4.5 0.0 4.2 0.0 0.2 0.0 1.6 305.7 2.0 0.0 0.8 3.2 34.5 1.2 135.2 0.0 0.0 29.8 0.0 1.0 0.5 0.8 132.3 5.7 0.0 84.3 40.4 0.7 0.1 1.3 0.0 1.2 1.7 0.9 3.7 1.2 0.4 0.0 1.9 0.0 423.7 171.5 PPP1R1C Inhibitor-1-like ENSG00000150722 "Protein phosphatase 1 regulatory inhibitor subunit 1C" Q8WVI7 2 181954241-182131398 "Predicted intracellular proteins" "Cell cycle, Cell division" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 21.1" "Group enriched" "Detected in many" 4 "Early spermatids: 168.5;Late spermatids: 219.8;Spermatocytes: 145.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA055043 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus" "HPA055043: AB_2797251" "unprognostic (1.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.54e-3)" "unprognostic (1.08e-2)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (2.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.57e-2)" "unprognostic (6.59e-3)" "unprognostic (1.13e-1)" "unprognostic (7.98e-2)" "unprognostic (3.70e-2)" "unprognostic (1.00e-3)" "unprognostic (7.68e-2)" "unprognostic (3.07e-2)" "unprognostic (9.75e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 21.1 0.3 1.0 0.0 0.8 0.1 0.0 0.7 0.8 0.0 0.3 0.0 0.4 0.0 1.4 1.0 0.0 1.8 0.0 0.0 3.7 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.1 0.7 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.4 0.4 0.3 1.0 0.7 0.8 1.4 0.1 0.1 0.3 0.1 12.8 8.7 6.2 0.0 0.3 0.6 1.2 2.8 1.1 0.3 0.3 40.6 17.2 8.1 3.7 0.0 3.1 0.0 0.5 1.9 2.5 168.5 1.7 0.1 0.6 6.1 0.0 1.1 11.0 6.6 2.4 4.6 0.8 0.0 0.0 0.0 18.5 0.6 0.0 19.4 0.4 10.2 0.8 0.0 219.8 5.9 0.3 3.6 1.9 3.6 12.0 0.0 3.5 0.7 23.1 0.1 0.7 0.0 0.3 0.0 0.7 1.6 1.7 0.0 0.4 0.8 145.1 2.6 1.3 0.3 2.5 0.0 0.8 0.6 1.0 PPP1R7 sds22 ENSG00000115685 "Protein phosphatase 1 regulatory subunit 7" Q15435 2 241149576-241183652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 968.8;Late spermatids: 1709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA034500, HPA034501" Supported Approved Nucleoli NA NA 960000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" Nucleoli "HPA034500: AB_2674192, HPA034501: AB_10670965" "unprognostic (1.63e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.16e-2)" "unprognostic (3.62e-2)" "unprognostic (4.38e-1)" "unprognostic (8.07e-3)" "unprognostic (5.01e-2)" "unprognostic (2.49e-1)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (1.15e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-1)" "unprognostic (4.51e-3)" "unprognostic (1.23e-1)" 59.0 55.9 71.3 54.4 94.7 68.1 50.2 65.5 82.4 46.4 68.3 66.0 58.8 48.5 61.4 80.3 81.3 40.2 100.5 77.5 69.4 64.6 76.0 53.9 78.7 67.2 67.2 37.5 60.0 55.8 42.6 44.5 65.7 94.5 64.2 58.0 63.1 54.0 100.4 64.3 61.0 55.0 66.5 48.7 58.9 158.2 67.2 66.8 65.1 64.4 80.8 58.9 52.9 75.1 117.6 69.5 77.4 98.3 149.7 149.0 106.4 126.3 114.7 85.2 119.8 38.1 145.6 60.0 37.1 108.9 128.0 112.1 127.9 119.6 130.2 156.4 126.1 105.1 112.4 151.4 96.3 147.0 105.9 116.0 92.7 101.1 74.2 115.7 128.5 121.0 108.0 86.2 202.0 155.8 132.0 112.6 106.3 185.7 64.5 90.4 200.9 121.9 159.6 116.7 104.6 82.8 67.6 157.4 120.3 86.4 93.8 156.7 127.7 76.8 72.5 146.1 103.4 90.8 59.6 162.8 215.2 154.1 103.7 107.9 84.9 108.9 64.6 87.6 68.3 71.6 76.5 77.1 81.3 66.5 58.5 67.6 66.5 75.8 96.2 48.4 121.5 89.9 71.3 94.7 65.5 82.4 77.5 69.4 67.2 67.2 65.7 66.5 67.2 75.1 50.5 57.7 54.5 17.6 47.9 27.8 48.6 126.2 25.6 41.5 44.6 36.8 98.4 45.8 105.5 44.1 16.7 89.6 46.9 53.4 121.3 90.6 968.8 83.6 39.3 45.9 25.7 48.0 33.8 145.9 92.4 47.5 34.7 53.4 59.5 48.9 32.9 49.9 100.5 32.0 19.4 68.7 109.9 40.7 46.3 1709.4 51.0 49.4 87.2 13.1 63.7 78.6 80.3 18.1 21.9 94.5 71.3 67.4 54.5 52.1 81.7 120.8 112.2 58.9 72.3 35.1 65.6 315.5 122.5 45.9 38.1 71.6 57.9 117.2 55.3 56.0 PPP1R9A "FLJ20068, KIAA1222, Neurabin-I" ENSG00000158528 "Protein phosphatase 1 regulatory subunit 9A" Q9ULJ8 7 94907202-95296415 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell type enhanced" "Detected in many" "Astrocytes: 294.1;Excitatory neurons: 262.8;Inhibitory neurons: 201.5;Oligodendrocyte precursor cells: 593.1;Oligodendrocytes: 308.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 6.8;NK-cell: 10.3" "Group enriched" "Detected in many" 9 "granulocytes: 6.8;NK-cells: 10.3" "Cell line enhanced" "Detected in many" "HAP1: 12.2;RH-30: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027726, HPA075591" Approved Approved "Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA027726: AB_1855653, HPA075591: AB_2732296" "unprognostic (1.05e-1)" "unprognostic (6.59e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (8.62e-2)" "unprognostic (6.19e-2)" "unprognostic (1.45e-1)" "prognostic favorable (7.17e-4)" "unprognostic (2.26e-2)" "unprognostic (1.89e-1)" "prognostic favorable (8.63e-6)" "unprognostic (2.74e-1)" "unprognostic (4.85e-2)" "unprognostic (8.47e-2)" "unprognostic (8.79e-3)" 1.7 7.0 13.0 0.9 20.1 0.2 4.9 6.0 14.5 2.7 0.3 8.2 1.7 3.0 4.9 1.6 5.7 2.4 5.2 14.4 7.5 4.7 0.4 3.7 0.3 5.9 6.9 3.3 8.8 6.7 4.6 2.5 8.0 2.3 3.8 18.5 9.6 2.8 4.9 0.5 2.2 2.2 6.6 1.8 4.9 6.7 10.2 0.5 6.6 4.9 0.3 2.6 0.5 13.9 0.0 11.0 6.6 7.6 0.0 0.0 5.3 0.5 0.1 1.0 0.8 6.1 3.7 0.0 9.0 0.5 0.6 0.0 12.2 0.0 1.2 0.0 4.5 11.4 4.5 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.8 4.8 0.1 0.0 5.5 4.9 1.8 0.0 11.8 0.0 10.7 9.2 7.3 7.4 0.0 0.9 1.4 4.0 2.1 0.0 0.0 0.1 4.4 0.1 4.0 7.3 11.5 0.0 0.2 0.0 0.9 6.8 0.0 0.4 0.0 0.0 0.2 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 10.3 0.1 0.3 0.0 0.1 13.0 20.1 6.0 14.5 14.4 7.5 5.9 6.9 8.0 6.6 10.2 13.9 4.5 41.7 66.6 294.1 2.4 0.4 0.9 0.0 0.6 58.2 24.4 12.2 127.7 18.6 16.5 47.8 56.3 21.6 3.3 15.7 3.9 25.1 17.9 40.3 4.5 6.8 38.9 2.5 262.8 7.0 3.1 9.4 21.4 57.1 5.7 39.5 7.9 1.5 1.7 1.7 201.5 15.0 4.1 0.6 0.3 15.3 2.5 0.8 7.2 41.2 0.0 46.9 3.1 593.1 308.4 6.6 14.4 0.7 2.7 4.8 1.8 9.6 20.6 88.9 0.0 118.4 9.2 25.1 12.6 0.5 0.9 33.1 1.7 22.9 15.7 2.6 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190048-52229518 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.76e-4)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 98.5 300.7 305.0 60.5 311.1 58.1 98.7 292.0 394.2 126.9 261.4 115.7 91.5 126.8 101.0 164.4 126.8 63.2 322.8 342.6 299.4 156.9 106.0 87.5 72.7 308.9 301.1 163.7 100.7 129.9 123.9 69.1 312.8 123.3 82.2 89.8 99.8 92.2 239.7 119.3 98.5 96.0 280.1 87.6 106.0 67.2 331.7 76.9 107.9 170.7 90.0 123.5 121.9 299.2 153.6 248.4 210.9 182.0 166.9 173.4 105.3 130.3 173.2 174.1 151.1 129.3 122.1 132.5 91.0 213.9 95.7 108.8 228.0 197.9 100.6 101.3 562.8 99.6 126.9 148.2 152.6 105.6 93.1 234.3 163.8 163.5 149.2 162.9 167.9 92.1 114.3 96.8 196.3 178.6 159.6 215.4 204.6 162.2 218.4 148.6 118.3 152.5 285.0 251.7 153.3 161.3 149.0 160.1 100.3 136.3 141.9 197.3 153.1 133.2 120.5 65.7 154.2 96.9 151.5 160.0 143.1 109.7 170.5 172.6 172.0 169.4 143.9 212.2 131.0 143.1 126.3 134.3 192.8 157.1 101.6 119.6 103.7 228.6 199.0 119.7 177.5 255.6 305.0 311.1 292.0 394.2 342.6 299.4 308.9 301.1 312.8 280.1 331.7 299.2 55.3 44.8 35.4 21.5 76.0 70.4 99.0 178.0 56.9 114.0 64.5 71.1 100.2 74.4 99.5 119.5 25.0 203.7 47.3 157.0 117.4 213.5 4.4 77.5 79.7 72.4 107.0 39.7 27.4 155.7 259.9 85.7 77.5 100.7 68.5 96.7 65.0 52.8 146.2 144.7 39.5 128.8 144.5 68.1 39.3 10.4 72.4 58.0 53.4 17.8 103.7 118.0 62.8 25.6 29.9 168.2 189.0 85.4 60.3 88.3 147.5 135.3 80.6 61.5 78.9 49.2 90.3 16.5 68.8 74.4 63.2 182.0 64.2 99.7 185.2 104.2 PPP2R2C "B55gamma, IMYPNO, MGC33570, PR52, PR55G" ENSG00000074211 "Protein phosphatase 2 regulatory subunit Bgamma" Q9Y2T4 4 6320578-6563600 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.2" "Group enriched" "Detected in many" 5 "Astrocytes: 61.0;Early spermatids: 67.4;Excitatory neurons: 203.3;Inhibitory neurons: 82.8;Late spermatids: 182.5;Oligodendrocytes: 94.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 31.4;A549: 46.1;CAPAN-2: 28.2;GAMG: 68.4;MCF7: 36.2;PC-3: 38.9;SCLC-21H: 39.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, HPA060473" Approved Approved Cytosol NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA042122: AB_2677859, HPA042770: AB_2678155, HPA060473: AB_2684291" "unprognostic (9.39e-2)" "unprognostic (7.10e-2)" "unprognostic (9.12e-2)" "unprognostic (1.14e-3)" "unprognostic (1.48e-1)" "unprognostic (5.91e-2)" "unprognostic (2.70e-4)" "prognostic unfavorable (4.94e-4)" "unprognostic (1.77e-1)" "unprognostic (3.90e-1)" "unprognostic (4.67e-2)" "unprognostic (2.77e-1)" "unprognostic (1.36e-13)" "unprognostic (2.52e-1)" "unprognostic (3.92e-2)" "unprognostic (2.66e-3)" "unprognostic (9.90e-3)" 0.8 6.2 72.9 0.6 86.7 0.0 1.4 42.1 106.2 18.0 0.0 1.1 0.8 27.0 7.4 35.9 9.9 0.4 2.5 85.7 44.5 0.3 0.1 0.1 0.3 52.5 52.7 0.6 0.7 1.5 22.6 0.1 55.1 5.0 0.3 10.9 5.3 14.5 0.8 34.0 1.2 11.9 62.3 0.3 0.8 7.3 66.9 2.7 0.1 0.9 3.1 0.9 11.5 91.2 31.4 46.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 28.2 0.0 19.0 0.0 68.4 13.7 20.0 0.7 0.0 0.0 2.4 0.0 3.2 3.7 0.7 0.0 0.1 6.6 11.4 0.0 0.0 0.0 0.1 4.2 0.0 0.1 6.6 36.2 0.0 0.1 2.2 0.6 38.9 0.0 0.0 1.2 0.0 0.1 39.1 7.5 1.5 0.1 0.0 1.1 18.9 0.1 0.0 0.2 22.7 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.9 86.7 42.1 106.2 85.7 44.5 52.5 52.7 55.1 62.3 66.9 91.2 0.2 0.0 0.0 61.0 0.0 14.7 0.4 0.8 4.6 11.0 1.9 0.4 4.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 67.4 0.8 5.7 0.6 0.0 0.0 203.3 0.2 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.1 3.3 82.8 0.0 0.0 0.0 1.1 182.5 6.8 0.0 0.0 4.7 0.0 6.5 0.0 14.1 94.6 2.4 0.0 4.5 0.0 1.3 0.0 0.2 0.0 3.1 0.0 0.0 2.5 2.3 1.6 6.5 22.0 0.0 0.2 0.1 0.0 0.2 PPP2R3A "PPP2R3, PR130, PR72" ENSG00000073711 "Protein phosphatase 2 regulatory subunit B''alpha" Q06190 3 135965728-136147894 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 51.2;skeletal muscle: 180.5;tongue: 117.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.3;Oligodendrocytes: 201.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 37.4;BJ hTERT+: 35.3;RPTEC TERT1: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035829, HPA035830, HPA065338" Uncertain Approved "Golgi apparatus" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" "HPA035829: AB_10696513, HPA035830: AB_10670121, HPA065338: AB_2685475" "unprognostic (3.35e-1)" "unprognostic (2.37e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.71e-1)" "unprognostic (4.04e-1)" "unprognostic (1.44e-4)" "unprognostic (9.43e-2)" "unprognostic (1.27e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (8.92e-2)" "prognostic favorable (1.15e-5)" "unprognostic (4.55e-2)" "unprognostic (3.06e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.91e-4)" 3.1 3.4 3.3 2.3 7.2 0.2 7.1 4.3 5.0 5.2 3.9 8.0 2.0 7.7 5.1 8.3 4.1 5.0 51.2 4.2 4.9 22.0 1.1 3.9 0.6 5.7 5.5 5.6 3.4 11.7 1.8 2.8 5.3 5.9 5.4 2.6 8.9 6.5 180.5 18.9 2.3 9.6 4.3 1.1 7.4 7.2 6.0 0.6 3.1 117.6 1.2 4.5 4.0 13.7 37.4 2.0 10.3 5.0 8.1 10.2 11.9 28.5 35.3 13.2 16.3 2.4 2.4 0.1 10.7 29.3 9.5 4.7 4.3 10.0 28.3 0.1 1.4 1.6 1.0 0.1 5.8 0.0 1.4 9.3 8.5 16.8 7.8 13.3 12.8 1.0 1.0 0.1 19.2 6.2 0.3 0.2 7.2 0.4 6.9 0.1 15.1 0.1 46.2 1.4 0.7 5.7 4.7 5.7 10.9 9.2 9.1 0.5 8.4 13.7 7.5 18.8 12.7 0.4 1.0 0.1 10.1 0.8 4.9 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.0 3.3 7.2 4.3 5.0 4.2 4.9 5.7 5.5 5.3 4.3 6.0 13.7 7.9 28.9 27.6 51.6 2.8 26.4 19.5 7.1 19.4 5.7 19.9 15.5 115.3 8.6 10.0 55.2 0.0 10.9 6.7 25.3 21.5 20.6 8.4 9.9 19.0 11.4 13.1 0.4 35.2 9.9 15.4 14.8 21.9 16.1 3.8 15.7 8.6 2.9 2.5 3.3 47.2 6.9 6.1 2.4 9.8 10.7 24.5 3.2 28.4 13.1 9.6 8.9 2.1 72.4 201.1 17.2 10.6 18.4 1.5 17.8 21.7 40.1 8.1 2.6 6.6 29.0 14.0 10.1 18.6 15.3 33.2 10.4 3.4 6.7 8.9 15.6 PPP2R3C "C14orf10, FLJ20644, G4-1, G5PR" ENSG00000092020 "Protein phosphatase 2 regulatory subunit B''gamma" Q969Q6 14 35085467-35122517 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 489.7;Late spermatids: 233.5;Spermatocytes: 239.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040835, HPA058834" Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Cytosol" "HPA040835: AB_10794152, HPA058834: AB_2683831" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (7.32e-3)" "unprognostic (5.33e-2)" "unprognostic (9.73e-2)" "unprognostic (1.10e-3)" "unprognostic (3.05e-1)" "unprognostic (7.85e-2)" "unprognostic (9.48e-3)" "unprognostic (1.17e-2)" "unprognostic (1.91e-1)" "unprognostic (2.18e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-3)" "unprognostic (8.55e-2)" "unprognostic (8.29e-2)" 19.9 15.5 23.5 23.9 25.0 42.8 17.1 24.4 41.6 18.1 23.3 18.6 21.0 16.2 16.4 12.5 14.0 18.6 22.9 23.8 25.6 14.4 16.1 17.7 31.0 25.3 24.4 15.9 10.2 17.0 17.6 18.8 25.6 17.1 20.3 15.4 13.5 14.1 24.9 7.1 22.5 21.0 24.9 24.4 16.2 71.6 24.4 26.4 12.4 25.7 25.9 22.3 10.4 27.5 41.2 21.8 41.7 33.9 32.4 54.5 29.6 33.0 32.0 41.0 48.0 18.1 32.2 47.2 13.4 33.9 15.5 17.6 20.0 13.8 60.5 47.8 19.3 26.2 11.9 65.2 43.3 51.2 51.7 41.9 14.4 29.0 19.7 24.0 55.7 26.2 25.7 46.3 57.4 28.4 46.4 43.1 37.1 27.4 24.3 50.2 27.1 32.8 15.8 24.1 39.9 37.5 41.7 27.6 57.8 19.9 17.9 57.0 47.9 41.3 17.3 36.0 34.9 44.8 52.4 92.8 22.8 47.9 48.1 66.5 41.6 86.9 23.4 52.5 27.0 31.0 24.8 29.5 36.1 33.1 22.0 26.9 76.9 33.1 42.7 16.3 40.8 34.0 23.5 25.0 24.4 41.6 23.8 25.6 25.3 24.4 25.6 24.9 24.4 27.5 35.5 16.0 24.7 32.7 40.2 11.5 23.3 31.7 9.6 15.9 18.8 14.7 26.3 17.2 25.8 20.2 4.2 19.4 48.1 29.1 33.2 31.2 489.7 23.1 28.1 33.8 31.2 69.7 28.3 36.1 26.2 26.5 19.9 21.7 33.7 31.3 34.6 22.8 61.3 8.4 30.4 26.8 32.6 49.7 36.3 233.5 28.3 42.6 28.4 24.4 71.5 28.7 46.4 36.2 58.8 49.2 22.3 30.5 37.4 24.8 37.8 43.2 25.1 21.5 32.9 24.0 43.1 239.2 58.6 19.6 13.5 34.8 45.2 36.2 24.6 30.5 PPP3R1 "CALNB1, CNB, CNB1" ENSG00000221823 "Protein phosphatase 3 regulatory subunit B, alpha" P63098 2 68178857-68256237 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 189.9" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005610, HPA047157" Approved Supported "Plasma membrane,Cytosol" NA NA 42000 "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Cytosol "CAB005610: AB_325975, HPA047157: AB_2679960" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (9.08e-6)" "unprognostic (5.90e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.59e-1)" "unprognostic (3.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (5.24e-3)" "unprognostic (5.35e-1)" "unprognostic (8.70e-2)" "unprognostic (1.24e-1)" 53.7 37.7 56.1 32.4 92.9 73.6 27.1 38.0 127.3 27.3 0.0 27.6 25.7 31.0 26.1 30.0 23.3 28.0 20.6 99.0 24.2 21.4 58.2 27.7 40.2 23.5 18.4 24.9 20.7 17.0 18.3 36.6 24.9 26.3 27.8 189.9 24.9 30.1 88.8 33.6 23.9 35.3 14.4 34.2 24.8 20.6 30.0 42.6 23.8 31.0 40.5 32.9 28.6 64.5 61.5 51.7 69.7 48.4 47.4 54.3 70.5 86.3 75.9 98.8 86.8 75.9 55.4 85.7 28.7 61.4 69.5 41.8 74.4 64.8 120.0 59.4 52.9 284.0 38.3 71.1 93.1 111.9 92.2 55.1 57.6 76.9 78.0 55.9 67.2 72.2 67.8 96.8 73.2 53.8 96.1 99.4 81.9 52.0 44.4 69.1 90.6 139.9 61.7 66.1 91.4 64.2 50.4 72.3 65.9 45.0 33.9 51.8 69.5 84.6 76.5 64.2 75.1 53.8 62.6 124.7 61.3 115.2 54.0 1.5 0.5 1.3 0.2 0.3 0.5 0.2 0.3 0.1 0.5 0.3 0.3 0.5 2.7 0.3 0.6 0.7 0.3 0.4 56.1 92.9 38.0 127.3 99.0 24.2 23.5 18.4 24.9 14.4 30.0 64.5 37.0 9.6 12.7 81.6 40.4 74.8 11.6 7.0 72.8 22.2 21.0 13.1 17.9 10.0 7.7 16.5 52.1 11.7 34.0 20.5 11.7 7.1 20.0 19.9 23.0 34.0 15.1 52.8 151.2 8.7 17.2 24.2 18.8 29.1 19.7 11.2 15.4 19.2 24.7 11.8 93.1 15.6 4.1 40.0 105.1 7.7 9.9 54.7 35.6 105.9 21.2 27.8 18.6 72.9 77.5 12.9 10.6 8.6 39.2 17.3 12.6 20.1 5.8 92.7 13.1 14.4 29.8 2.9 6.1 64.0 70.5 12.0 39.9 14.2 13.2 21.3 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRCC RCCP1 ENSG00000143294 "Proline rich mitotic checkpoint control factor" Q92733 1 156750610-156800815 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017151, HPA019463, HPA019481" Supported Enhanced "Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" "CAB017151: , HPA019463: AB_1855672, HPA019481: AB_1855673" "unprognostic (6.12e-2)" "unprognostic (2.68e-1)" "unprognostic (2.68e-3)" "prognostic unfavorable (5.55e-4)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (8.63e-4)" "unprognostic (3.03e-1)" "unprognostic (9.16e-2)" "unprognostic (3.27e-3)" "unprognostic (1.14e-1)" "unprognostic (6.80e-2)" "prognostic unfavorable (8.99e-15)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.02e-2)" 31.9 31.8 43.4 29.7 45.2 41.9 31.4 44.5 50.4 32.4 42.3 36.6 27.0 34.5 23.1 39.7 29.7 23.0 37.6 45.7 42.0 36.7 34.2 29.6 36.3 43.3 42.8 30.9 29.0 34.7 28.1 29.0 43.7 33.5 22.5 26.6 30.4 24.1 63.4 43.2 30.9 27.3 41.3 37.4 31.8 27.0 43.3 37.5 31.0 34.4 30.7 32.6 32.2 46.9 79.1 67.3 51.6 59.5 42.5 33.8 89.8 53.8 52.8 59.3 50.8 106.2 65.0 80.6 90.4 43.1 34.1 80.3 74.7 57.0 45.3 101.6 97.4 59.1 47.4 68.4 52.5 81.9 66.6 48.1 64.7 51.5 46.6 45.7 55.2 52.5 99.7 72.1 41.8 140.2 94.1 94.6 124.9 108.9 82.0 81.6 45.7 108.7 62.5 74.0 91.6 163.4 57.0 140.6 92.4 84.4 102.7 129.8 51.1 59.3 61.9 66.0 89.6 184.6 298.5 124.1 58.7 52.2 56.1 46.9 28.6 57.4 27.5 29.9 26.5 24.0 24.7 30.0 32.5 27.6 24.0 25.2 27.7 30.2 37.1 38.9 27.1 26.0 43.4 45.2 44.5 50.4 45.7 42.0 43.3 42.8 43.7 41.3 43.3 46.9 22.2 9.6 16.4 12.7 32.0 52.4 38.2 52.1 46.1 19.8 31.1 24.4 13.0 18.6 29.4 20.2 22.9 63.1 36.0 27.2 21.5 39.4 13.5 21.4 21.9 30.2 34.3 16.6 15.9 32.2 63.4 28.7 24.5 23.2 17.1 28.9 25.4 16.0 44.0 28.6 14.4 26.9 40.7 22.6 27.4 10.4 30.4 28.4 21.4 9.4 44.9 16.9 30.9 18.1 25.4 35.5 34.2 28.6 48.8 43.8 29.8 29.9 21.5 19.8 32.9 32.2 29.2 43.3 46.2 39.6 51.3 101.1 30.3 32.4 29.4 39.2 PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089241-123194266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9;urinary bladder: 9.0" "Cell type enhanced" "Detected in some" "Astrocytes: 15.0;Endometrial stromal cells: 6.5;Excitatory neurons: 7.9;Fibroblasts: 10.7;Late spermatids: 7.1;Oligodendrocytes: 11.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;HEK 293: 5.2;HEL: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.3" HPA030324 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA030324: AB_10670032" "unprognostic (2.33e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-7)" "unprognostic (9.30e-4)" "unprognostic (1.10e-1)" "unprognostic (3.43e-4)" "unprognostic (1.27e-1)" 0.7 0.1 0.2 0.3 0.2 0.0 0.6 0.2 0.3 0.9 0.6 4.9 0.2 0.7 0.1 0.6 0.4 3.3 0.5 0.1 0.2 0.3 0.1 2.9 0.0 0.3 0.4 1.9 0.3 0.1 0.3 4.2 0.4 1.3 1.0 0.2 0.1 0.1 0.1 0.2 0.6 0.7 0.3 0.0 0.6 0.3 0.2 0.0 0.8 0.2 0.2 9.0 0.6 0.3 0.0 0.0 0.0 0.3 0.3 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.1 5.2 1.1 0.5 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.4 0.4 0.3 0.2 0.3 0.5 0.0 0.0 15.0 0.0 1.9 0.1 0.0 0.0 1.0 0.6 0.3 1.4 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.1 3.3 0.6 6.5 0.5 0.0 0.0 7.9 0.2 0.3 10.7 0.0 0.5 0.0 2.4 0.0 0.5 0.8 0.0 6.4 0.1 0.0 0.8 3.5 7.1 2.1 0.4 3.6 4.7 0.8 0.2 0.0 3.0 11.0 0.1 0.0 1.2 0.1 0.2 0.0 0.8 0.2 1.0 0.0 0.7 2.2 2.3 4.4 0.2 1.3 0.4 0.4 6.1 0.0 0.1 PREP ENSG00000085377 "Prolyl endopeptidase" P48147 6 105273218-105454062 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.7;Syncytiotrophoblasts: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025414, HPA031388, HPA031389, HPA031390" Supported Supported Cytosol NA NA 1700000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB025414: , HPA031388: AB_2673855, HPA031389: AB_2673856, HPA031390: AB_2673857" "unprognostic (3.05e-2)" "unprognostic (9.09e-3)" "unprognostic (2.85e-2)" "unprognostic (5.46e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.33e-4)" "unprognostic (2.63e-3)" "unprognostic (2.39e-1)" "unprognostic (6.78e-2)" "unprognostic (5.81e-2)" "unprognostic (2.66e-2)" "unprognostic (1.15e-1)" "unprognostic (4.47e-3)" "unprognostic (2.74e-2)" "unprognostic (8.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" 17.3 17.4 7.2 14.6 8.1 14.3 17.7 7.4 12.0 15.2 7.8 32.1 23.6 15.8 12.1 21.1 13.0 8.7 22.5 8.8 7.3 11.3 19.0 16.2 13.6 6.7 7.7 16.0 19.2 20.5 13.0 17.8 6.8 11.6 37.5 15.4 18.6 9.0 84.8 33.4 25.6 15.3 6.6 14.3 18.7 21.4 8.8 16.4 12.3 46.9 16.2 21.4 17.5 8.5 22.3 26.9 27.9 32.1 63.1 37.1 27.7 28.6 27.0 37.2 39.0 35.9 14.2 28.5 26.8 33.9 35.0 33.3 41.8 86.5 42.7 41.8 37.4 38.1 21.7 40.0 25.3 40.5 26.2 35.8 53.4 27.6 71.7 28.0 35.4 50.1 67.4 49.8 45.5 38.8 25.8 41.4 27.9 44.2 25.0 41.1 48.4 18.3 28.2 53.8 36.0 51.8 25.3 42.0 21.7 35.3 17.9 61.9 36.1 17.3 23.9 21.6 36.2 14.2 9.7 38.5 30.4 42.6 56.6 5.5 15.2 8.4 16.3 16.8 16.8 9.3 14.2 17.1 16.5 6.9 12.9 15.5 0.8 19.9 22.7 7.0 13.6 13.5 7.2 8.1 7.4 12.0 8.8 7.3 6.7 7.7 6.8 6.6 8.8 8.5 6.3 3.2 6.7 22.9 10.1 10.8 6.8 12.0 5.7 5.1 6.0 5.5 14.8 7.2 13.6 7.3 14.6 28.2 14.5 19.3 5.9 10.4 1.4 6.6 15.1 10.1 19.3 11.2 79.7 11.7 35.9 10.6 24.5 11.6 13.4 11.2 7.5 15.1 15.0 13.5 48.3 29.4 10.2 14.2 10.8 3.2 10.8 13.3 5.4 27.2 19.1 3.3 5.2 28.6 18.7 18.0 29.1 9.1 11.0 5.3 18.5 8.8 4.8 10.4 0.0 8.3 10.3 3.9 18.8 12.9 8.5 67.9 16.1 14.4 38.2 8.5 PREX1 "KIAA1415, P-REX1" ENSG00000124126 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1" Q8TCU6 20 48624252-48827999 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.5;brain: 78.1" "Cell type enhanced" "Detected in many" "Astrocytes: 87.1;dendritic cells: 84.0;Kupffer cells: 104.7;Macrophages: 76.5;Microglial cells: 95.5;NK-cells: 90.6;Oligodendrocytes: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 157.9;SK-BR-3: 162.2;T-47d: 145.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001927 Supported Supported Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "HPA001927: AB_1079674" "unprognostic (8.07e-2)" "unprognostic (3.16e-2)" "unprognostic (2.15e-2)" "unprognostic (2.55e-1)" "unprognostic (7.47e-2)" "prognostic favorable (8.56e-4)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" "unprognostic (5.21e-2)" "unprognostic (1.13e-2)" "unprognostic (2.70e-2)" "unprognostic (5.86e-3)" "unprognostic (6.84e-2)" "unprognostic (2.31e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-2)" 14.8 10.6 32.8 37.4 56.4 52.5 15.0 43.2 47.2 12.3 1.2 7.0 6.3 4.0 1.4 6.4 4.7 13.0 6.7 32.1 42.0 4.8 5.2 26.8 36.6 52.1 52.0 2.5 5.3 6.9 7.6 11.7 53.8 4.8 6.0 3.9 5.3 3.4 6.6 3.5 12.7 7.7 43.5 42.9 8.8 6.0 45.3 9.8 9.4 8.6 21.8 12.3 3.2 78.1 2.3 6.1 78.4 0.0 1.3 5.7 27.2 2.7 3.5 11.2 2.8 0.4 0.3 16.4 49.5 7.2 21.4 1.0 4.1 0.2 7.5 3.7 2.0 2.4 8.8 0.0 4.6 9.0 51.1 6.3 0.0 25.7 0.0 7.6 68.4 7.2 0.2 0.6 14.8 157.9 0.2 24.7 3.1 8.1 6.4 24.1 22.8 9.8 0.5 0.0 16.5 2.4 14.7 162.2 17.8 4.4 145.0 67.4 77.2 4.5 15.6 0.2 4.6 0.9 3.5 20.1 72.4 17.8 24.3 4.5 1.9 2.2 3.7 2.2 2.2 1.5 2.0 3.2 1.6 1.4 0.3 1.1 9.2 1.8 2.0 1.3 7.3 2.0 32.8 56.4 43.2 47.2 32.1 42.0 52.1 52.0 53.8 43.5 45.3 78.1 43.2 3.2 6.6 87.1 35.4 2.5 0.3 0.4 1.2 0.3 40.0 21.5 3.7 2.8 2.6 1.8 8.4 0.7 84.0 0.9 0.0 0.2 3.5 3.5 4.7 24.5 1.2 14.1 13.3 1.2 4.4 10.3 4.1 6.2 1.3 0.7 20.7 1.9 32.1 0.0 4.6 1.8 0.0 104.7 28.2 2.9 0.9 76.5 8.8 95.5 47.1 19.4 90.6 49.3 190.2 0.1 1.0 0.4 23.3 0.7 0.3 0.2 4.5 0.7 0.0 18.1 3.3 2.2 11.6 0.4 2.4 9.3 63.9 41.2 4.5 0.7 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRICKLE1 "EPM1B, FLJ31937, RILP" ENSG00000139174 "Prickle planar cell polarity protein 1" Q96MT3 12 42456757-42590355 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 72.8;Excitatory neurons: 307.7;Inhibitory neurons: 122.2;Microglial cells: 64.6;Oligodendrocyte precursor cells: 114.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.6;naive B-cell: 11.5" "Lineage enriched" "Detected in many" 4 "B-cells: 11.5" "Cell line enriched" "Detected in many" 18 "HBEC3-KT: 1015.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001379, HPA050037" Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA001379: AB_1855703, HPA050037: " "unprognostic (2.44e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.22e-1)" "unprognostic (2.34e-4)" "unprognostic (3.53e-1)" "unprognostic (1.69e-2)" "unprognostic (5.89e-2)" "unprognostic (5.29e-2)" "unprognostic (7.77e-2)" "unprognostic (1.21e-3)" "unprognostic (2.29e-4)" "unprognostic (1.12e-1)" "unprognostic (8.95e-3)" "unprognostic (5.33e-4)" 6.3 3.0 3.7 5.2 5.0 1.7 5.0 0.0 7.2 12.5 0.0 4.2 2.6 12.1 1.6 2.4 6.4 10.0 13.8 4.2 0.0 5.0 1.7 9.5 4.6 0.1 1.3 12.5 2.0 1.4 2.0 5.3 0.0 5.1 2.2 4.2 7.8 5.6 3.9 4.7 2.4 12.7 0.0 14.8 2.9 6.0 3.9 1.6 7.9 4.6 3.4 5.5 6.3 1.0 7.7 4.4 17.0 0.5 12.4 13.1 0.5 11.0 5.2 3.0 5.1 0.5 16.0 0.5 31.4 1.6 0.0 2.9 12.5 1015.4 3.5 0.6 6.4 17.5 0.9 0.4 1.7 0.3 0.2 19.3 7.5 12.7 1.7 1.8 39.7 0.3 1.8 3.1 2.9 0.3 0.1 0.5 56.1 0.1 18.0 0.2 0.7 0.1 21.1 0.7 4.4 3.0 0.3 0.7 0.7 13.7 0.3 35.1 2.9 0.9 13.4 14.0 14.2 0.9 0.6 6.1 0.2 10.7 0.6 2.6 1.8 0.4 0.2 1.0 0.7 7.6 0.2 0.2 1.0 11.5 0.4 0.2 2.4 0.5 0.6 1.6 0.2 0.9 3.7 5.0 0.0 7.2 4.2 0.0 0.1 1.3 0.0 0.0 3.9 1.0 6.9 16.0 8.2 8.8 13.2 2.7 5.3 7.3 4.0 13.5 4.0 2.2 5.7 14.3 2.6 1.8 2.1 0.6 0.2 0.0 0.0 3.8 72.8 5.2 43.0 8.1 0.0 0.4 307.7 2.6 0.2 19.2 3.6 8.6 1.3 59.1 14.6 0.1 0.6 8.4 122.2 0.0 2.0 0.9 2.3 25.4 9.9 1.2 7.2 64.6 1.1 2.7 0.0 114.6 5.3 3.9 0.1 24.8 3.1 1.0 0.0 3.3 0.3 4.5 0.0 3.8 7.9 5.1 4.8 1.9 1.4 0.7 1.1 18.6 0.0 0.8 PRICKLE3 LMO6 ENSG00000012211 "Prickle planar cell polarity protein 3" O43900 X 49174802-49186528 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 60.8;Late spermatids: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA000998 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" "HPA000998: AB_1079258" "unprognostic (9.83e-3)" "unprognostic (7.02e-2)" "unprognostic (6.97e-3)" "unprognostic (2.54e-1)" "unprognostic (1.12e-2)" "unprognostic (5.61e-2)" "unprognostic (2.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.89e-1)" "unprognostic (2.41e-2)" "unprognostic (3.78e-2)" "unprognostic (1.14e-3)" "prognostic unfavorable (5.73e-6)" "unprognostic (2.28e-3)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "prognostic favorable (4.84e-5)" 4.3 3.8 2.3 3.5 2.5 2.1 4.0 2.5 2.9 4.8 4.2 3.7 3.0 4.0 1.7 10.2 4.7 2.9 5.7 2.1 2.4 2.5 3.1 4.0 3.3 2.7 2.7 2.6 5.1 4.0 2.1 3.8 2.7 4.6 3.0 0.6 4.5 5.8 11.6 12.0 3.5 3.3 2.9 3.8 4.0 1.1 2.7 3.4 3.9 10.5 4.5 5.1 6.6 3.0 17.7 20.3 0.5 1.7 8.4 9.1 19.0 6.8 10.2 5.1 7.9 6.2 10.9 0.0 6.1 8.4 1.6 24.8 15.6 25.1 2.3 21.9 8.4 7.4 12.2 4.7 12.2 5.0 24.3 8.3 19.3 6.4 15.7 3.3 5.3 4.5 12.4 6.6 8.6 27.8 6.0 7.4 3.0 10.6 21.7 8.3 5.3 9.8 6.7 24.7 3.4 0.0 9.4 8.6 6.7 6.0 17.4 5.6 6.2 0.1 8.0 7.2 2.6 11.6 8.3 4.1 8.0 6.6 0.1 2.4 8.3 9.2 2.3 9.1 3.2 7.0 3.1 3.8 7.5 4.1 2.5 2.6 4.7 3.0 12.1 3.5 4.2 5.1 2.3 2.5 2.5 2.9 2.1 2.4 2.7 2.7 2.7 2.9 2.7 3.0 2.7 0.0 1.5 1.0 4.2 15.2 5.5 13.7 10.8 0.3 1.4 2.2 1.5 0.0 6.6 1.8 2.1 3.2 1.0 1.9 1.9 3.4 60.8 2.7 2.0 3.2 1.2 2.5 0.2 2.7 6.8 2.8 6.6 2.4 0.0 1.7 1.4 1.4 2.5 0.0 0.1 3.3 8.2 1.3 8.1 100.8 1.5 2.8 8.8 0.0 2.9 0.9 1.0 2.0 1.0 2.2 2.7 0.7 3.2 4.8 1.7 2.0 3.3 0.2 0.0 1.5 2.6 0.4 0.5 15.9 19.0 3.3 2.2 2.2 2.5 4.6 PRIM1 ENSG00000198056 "DNA primase subunit 1" P49642 12 56731296-56752374 "Predicted intracellular proteins" "DNA replication, Transcription" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 28.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.4;Spermatocytes: 118.2;Spermatogonia: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040010 Uncertain NA Yes "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA040010: AB_10805599" "unprognostic (3.04e-3)" "unprognostic (1.67e-2)" "unprognostic (2.12e-2)" "unprognostic (1.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (2.40e-8)" "unprognostic (4.68e-2)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (1.56e-1)" "unprognostic (1.82e-1)" "unprognostic (1.98e-3)" "unprognostic (3.94e-1)" "unprognostic (2.16e-1)" "unprognostic (5.35e-2)" "unprognostic (6.53e-2)" 3.7 3.2 2.0 7.0 2.8 28.2 9.9 5.5 2.8 3.7 1.2 7.9 4.5 5.0 4.2 4.4 5.3 2.9 2.3 1.9 2.0 3.0 7.5 4.9 12.3 2.5 2.2 8.9 6.1 6.1 2.1 4.8 2.6 3.6 11.2 8.3 3.9 3.9 4.6 7.8 7.7 5.8 2.0 6.9 5.4 14.4 2.3 18.8 5.0 5.6 14.4 3.8 3.1 4.3 43.0 37.9 52.1 29.2 5.1 9.1 57.8 34.7 28.7 62.1 59.8 42.0 54.4 83.0 27.4 15.8 26.0 40.4 60.3 39.9 68.8 40.7 40.4 106.2 22.6 36.8 1.2 129.3 43.2 4.2 7.2 55.8 22.1 8.8 22.6 92.1 105.5 123.8 35.4 33.6 76.8 54.4 53.5 32.0 47.1 85.0 81.4 70.9 15.0 35.4 51.0 46.0 41.4 20.6 19.9 36.2 67.2 52.8 10.9 32.2 70.7 33.1 46.4 45.1 94.5 45.3 19.4 55.4 40.9 2.5 1.9 4.4 9.1 4.0 9.5 11.3 11.2 8.5 3.9 12.2 14.0 10.7 1.0 6.8 7.1 7.5 10.0 5.3 2.0 2.8 5.5 2.8 1.9 2.0 2.5 2.2 2.6 2.0 2.3 4.3 6.9 6.4 6.8 4.6 10.4 3.8 10.7 10.0 4.6 5.1 7.0 7.2 3.2 2.8 6.1 7.3 6.2 14.9 8.7 2.5 0.0 5.8 6.2 4.1 3.9 6.4 1.2 56.4 5.7 7.2 27.0 5.4 5.6 3.3 3.8 10.0 5.7 4.7 11.8 20.2 10.6 4.6 2.0 8.1 3.1 4.3 7.2 6.5 3.6 2.8 7.9 5.7 8.2 8.0 7.8 2.7 2.2 4.9 9.7 2.2 2.0 2.5 6.0 12.7 13.1 8.2 8.8 118.2 107.2 5.1 4.0 4.5 12.8 3.0 9.4 5.0 PRIM2 PRIM2A ENSG00000146143 "DNA primase subunit 2" P49643 6 57314805-57646850 "Plasma proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 30.6" "Cell type enhanced" "Detected in many" "Microglial cells: 70.3;Oligodendrocyte precursor cells: 56.8;Oligodendrocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046566 Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA046566: AB_2679701" "unprognostic (1.24e-1)" "unprognostic (1.55e-2)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.98e-4)" "unprognostic (3.08e-1)" "unprognostic (6.24e-2)" "prognostic unfavorable (3.44e-5)" "unprognostic (2.31e-1)" "unprognostic (1.00e-2)" "prognostic favorable (3.00e-5)" "prognostic unfavorable (5.25e-4)" "unprognostic (3.89e-1)" "prognostic unfavorable (7.34e-6)" "unprognostic (2.04e-2)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-1)" 4.3 3.3 3.9 6.6 4.6 15.0 6.9 6.0 4.3 5.6 6.9 6.9 6.0 7.2 6.9 4.3 6.2 4.3 3.3 3.9 5.6 3.9 5.0 4.8 10.6 4.2 4.7 7.2 4.0 3.9 1.9 7.5 4.4 30.6 8.4 4.0 4.2 5.6 2.3 5.8 5.2 8.0 2.8 5.5 4.8 6.5 4.5 15.3 4.4 2.4 11.8 5.8 4.1 7.1 44.8 17.7 34.1 37.6 16.8 29.5 27.3 53.1 48.8 57.0 74.7 26.6 21.1 39.4 27.7 66.6 39.6 27.9 30.2 29.2 71.6 35.1 24.2 47.6 22.7 43.0 7.3 43.5 27.4 12.1 12.0 61.0 20.3 14.2 26.9 44.1 46.2 38.9 48.3 28.2 49.8 37.6 22.0 37.1 17.2 34.7 46.9 31.2 21.0 20.7 24.5 19.2 31.5 15.9 21.3 38.9 33.3 47.4 17.9 54.7 55.5 106.2 44.2 14.4 29.3 47.2 26.6 50.5 30.4 0.7 1.9 1.8 4.1 3.7 4.3 3.5 3.5 5.4 3.0 4.0 2.8 5.7 1.4 5.2 4.2 5.1 4.7 2.1 3.9 4.6 6.0 4.3 3.9 5.6 4.2 4.7 4.4 2.8 4.5 7.1 5.9 0.0 2.7 30.0 11.2 4.0 6.7 4.1 11.4 5.6 6.2 4.2 1.1 2.8 4.6 3.7 12.5 17.0 15.1 4.3 3.9 5.1 10.3 4.9 7.1 5.0 1.2 26.5 38.0 5.2 22.0 6.9 4.1 6.0 12.0 13.7 4.2 3.5 9.3 6.7 32.6 6.5 10.2 6.6 6.4 3.7 6.5 7.0 0.0 70.3 7.3 4.8 17.5 56.8 54.5 4.9 5.3 6.8 12.7 7.1 4.4 1.8 4.1 5.6 19.7 4.9 6.8 10.1 11.2 8.7 3.0 5.7 13.6 8.0 8.6 5.3 PRKCB "PKCβ, PKCB, PRKCB1, PRKCB2" ENSG00000166501 "Protein kinase C beta" P05771 16 23835983-24220611 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Adaptive immunity, Apoptosis, Immunity, Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.0;lymphoid tissue: 47.2" "Cell type enhanced" "Detected in many" "B-cells: 185.1;Bipolar cells: 208.6;Excitatory neurons: 877.7;Inhibitory neurons: 320.2;Kupffer cells: 221.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 95 "amygdala: 28.9;basal ganglia: 53.9;cerebral cortex: 84.0;hippocampal formation: 35.3;white matter: 36.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 161.8;HMC-1: 154.8;K-562: 234.9;THP-1: 72.7;U-937: 64.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003843, HPA048321, HPA054203" Approved Supported Nucleoplasm,Cytosol NA NA 380000 "Cluster 6: Non-specific - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB003843: AB_562197, HPA048321: AB_2680357, HPA054203: AB_2682416" "unprognostic (1.53e-3)" "unprognostic (4.53e-4)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (1.72e-1)" "unprognostic (7.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-2)" "unprognostic (1.79e-1)" "unprognostic (7.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (2.12e-2)" "unprognostic (3.28e-1)" "unprognostic (4.95e-2)" 4.4 1.6 28.9 30.8 53.9 32.1 1.5 0.5 84.0 4.2 0.0 9.7 5.9 3.8 0.6 3.5 3.8 4.4 1.1 35.3 0.0 2.8 4.2 7.8 47.1 0.0 0.0 0.6 1.0 0.2 1.4 2.7 0.0 7.3 5.1 18.2 1.5 10.2 0.8 5.5 19.4 7.2 0.0 46.2 5.7 8.4 0.0 47.2 4.5 1.0 40.0 8.7 1.7 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 1.0 0.0 0.3 0.5 0.5 0.0 0.0 0.0 3.2 161.8 7.5 0.0 0.0 23.6 154.8 0.0 0.7 0.0 0.0 0.0 0.0 27.3 234.9 0.6 0.0 0.0 52.1 51.4 1.5 0.0 0.0 49.0 0.4 9.5 0.5 14.1 27.2 0.0 0.2 0.2 2.4 0.8 0.0 72.7 1.1 0.0 0.3 0.1 0.0 4.1 0.0 1.4 0.2 64.4 0.3 39.3 13.3 27.8 24.8 20.0 11.5 44.2 15.9 29.9 11.3 40.0 13.0 32.0 39.1 39.9 28.6 33.8 12.7 15.5 28.9 53.9 0.5 84.0 35.3 0.0 0.0 0.0 0.0 0.0 0.0 36.6 1.1 3.2 4.9 21.5 185.1 6.0 4.1 0.1 0.6 208.6 0.9 0.8 2.0 2.8 1.8 1.8 2.1 0.2 166.3 1.4 0.0 0.0 26.5 0.1 0.1 4.1 0.0 26.3 877.7 0.2 0.3 1.7 1.5 0.1 71.5 1.9 11.4 3.1 50.5 79.1 320.2 1.5 0.0 221.9 20.5 11.7 0.0 100.9 3.6 110.5 154.4 10.8 120.5 102.1 132.5 0.0 9.6 0.4 61.8 1.0 6.7 0.8 1.6 9.9 0.0 4.4 1.6 3.4 3.6 0.5 14.3 0.8 68.1 0.2 3.8 4.5 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 33.6;skeletal muscle: 124.5;tongue: 112.6" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;dendritic cells: 22.4;NK-cells: 32.0;Oligodendrocyte precursor cells: 24.6;Oligodendrocytes: 75.2;T-cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 23.0;MAIT T-cell: 18.0;memory CD4 T-cell: 24.5;memory CD8 T-cell: 24.5;naive CD4 T-cell: 19.1;naive CD8 T-cell: 17.9;NK-cell: 13.3;T-reg: 39.7" "Group enriched" "Detected in many" 11 "NK-cells: 13.3;T-cells: 39.7" "Cell line enhanced" "Detected in many" "HEL: 57.8;JURKAT: 40.0;MOLT-4: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Centriolar satellite" "HPA065279: AB_2685453, HPA073098: AB_2686571" "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (3.51e-2)" 0.8 0.7 5.3 5.2 8.5 5.7 0.9 6.1 6.3 1.6 12.1 1.4 1.5 2.5 8.3 2.2 3.9 1.5 0.3 5.5 8.2 10.9 1.0 5.3 12.3 6.5 8.6 1.3 3.4 0.7 0.8 0.2 6.4 1.8 1.7 1.5 1.4 1.1 124.5 0.3 3.3 0.7 5.5 5.0 2.1 1.1 7.2 33.6 14.9 112.6 9.4 2.2 0.6 9.8 0.1 5.3 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.2 0.4 3.4 0.3 0.0 0.0 0.0 0.0 3.3 6.0 0.0 0.0 3.9 57.8 0.0 0.4 0.7 2.8 0.6 0.3 3.5 0.1 0.2 0.0 0.5 40.0 12.8 0.1 0.0 0.0 43.9 8.0 5.8 0.5 0.0 8.5 1.3 0.0 11.6 2.9 0.4 2.1 0.0 0.0 0.0 3.4 0.0 5.8 0.0 0.0 5.6 0.0 0.0 0.1 0.0 0.0 0.0 7.1 0.0 2.4 0.1 0.3 23.0 0.4 18.0 0.1 24.5 24.5 0.2 0.0 19.1 17.9 1.6 13.3 0.0 0.0 39.7 10.5 5.3 8.5 6.1 6.3 5.5 8.2 6.5 8.6 6.4 5.5 7.2 9.8 0.2 3.2 7.0 22.9 0.8 0.0 0.3 0.3 0.6 1.6 0.3 0.3 0.4 0.0 0.7 1.8 0.0 0.0 22.4 0.0 7.9 0.3 2.1 0.5 1.2 0.2 1.8 8.0 13.7 0.8 0.1 0.7 1.5 3.0 1.3 8.2 1.1 0.0 0.5 0.0 14.7 0.5 0.0 1.3 0.5 5.6 0.0 1.7 0.0 7.5 0.8 1.2 32.0 24.6 75.2 0.1 0.1 0.0 10.2 0.2 0.0 0.3 0.9 0.4 0.0 4.2 0.4 1.0 2.2 0.5 0.0 0.0 31.7 0.3 0.4 0.1 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050411-2185395 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Group enriched" "Detected in many" 4 "Late spermatids: 708.3;Syncytiotrophoblasts: 1107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 16.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in many" "BEWO: 44.5;OE19: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favorable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.7 11.1 23.6 4.6 25.7 2.1 5.6 58.0 41.3 4.3 0.0 13.2 29.3 2.2 7.8 16.0 9.5 4.4 9.7 23.7 10.2 16.0 11.0 31.6 8.0 18.6 8.3 2.7 12.5 14.7 17.6 43.8 19.0 8.4 11.3 14.8 10.8 3.9 0.3 13.8 28.0 1.6 5.6 10.5 8.9 31.9 7.2 3.7 21.8 0.6 7.8 5.8 8.0 24.8 14.7 9.7 3.4 17.2 0.0 0.0 44.5 1.2 0.5 11.1 0.7 23.8 31.0 0.1 27.4 3.9 9.4 25.4 20.5 25.5 7.9 1.0 21.8 0.0 15.2 33.5 3.2 0.1 11.0 0.6 14.9 0.0 8.6 0.0 0.0 4.0 6.6 0.2 0.2 17.9 0.9 0.0 6.4 41.9 22.5 0.0 0.0 5.1 18.6 16.0 24.1 18.7 11.6 27.5 5.2 28.7 17.7 4.0 0.0 0.1 13.1 0.1 0.1 6.8 1.3 0.3 1.2 0.3 16.8 0.3 0.0 16.3 0.5 0.3 2.5 0.3 0.9 0.6 0.0 0.4 0.8 0.3 1.1 0.9 0.0 0.3 0.9 0.3 23.6 25.7 58.0 41.3 23.7 10.2 18.6 8.3 19.0 5.6 7.2 24.8 0.9 121.8 72.2 2.3 6.5 13.0 11.8 11.0 10.2 27.1 11.3 11.0 1.4 5.7 21.1 7.3 4.2 118.7 7.5 48.9 7.9 12.3 224.4 14.0 4.7 6.3 10.2 6.6 39.5 10.7 66.3 3.1 17.9 11.7 8.2 12.5 10.0 16.5 14.5 62.2 35.2 25.5 10.2 0.8 2.9 708.3 9.6 4.4 7.2 2.8 4.5 19.1 8.2 13.0 41.3 14.2 45.7 8.6 7.4 19.5 78.4 24.7 22.1 25.9 0.0 0.3 4.1 28.3 28.4 13.4 13.4 1107.9 9.8 2.6 31.3 14.3 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "liver: 598.5" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 432.9" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.7" "Cell line enriched" "Detected in some" 16 "Hep G2: 156.1" "Low region specificity" "Detected in all" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" NA NA 5200000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.2 0.0 0.6 0.1 1.1 1.1 0.1 0.6 1.0 0.4 0.0 1.0 0.8 0.1 0.1 0.1 0.2 0.6 0.1 0.6 1.0 14.8 598.5 0.2 0.6 1.6 0.8 0.2 0.3 0.0 0.3 0.1 1.5 0.2 0.6 0.2 0.2 0.1 0.2 0.6 0.8 0.0 0.4 0.4 2.6 0.1 0.8 0.6 0.2 0.0 0.3 0.4 0.2 1.1 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.1 0.0 0.9 0.1 0.4 9.5 0.0 0.3 0.0 0.0 0.2 0.1 7.8 156.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.6 0.4 2.3 0.7 0.0 0.1 0.0 0.0 0.9 0.4 0.0 1.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 59.7 0.0 0.3 0.6 1.1 0.6 1.0 0.6 1.0 1.6 0.8 1.5 0.4 0.8 1.1 0.0 0.0 0.0 0.3 4.1 0.8 0.4 11.2 0.0 0.0 0.1 0.0 0.4 47.1 1.2 0.0 0.0 0.0 24.0 3.9 5.9 0.5 0.1 3.4 0.1 0.6 10.3 18.7 0.1 0.2 0.0 0.7 2.0 0.2 0.0 0.0 12.1 432.9 3.7 0.0 0.5 9.3 0.0 9.3 4.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 8.1 0.0 0.0 0.0 3.8 84.8 3.4 0.0 0.0 0.2 0.3 0.1 0.2 0.0 0.1 0.1 1.1 0.0 1.8 0.3 PROM1 "AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4" ENSG00000007062 "Prominin 1" O43490 4 15963076-16084378 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 272.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 581.7;Respiratory ciliated cells: 144.8;Rod photoreceptor cells: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 37.2;CACO-2: 70.6;CAPAN-2: 28.9;EFO-21: 62.2;NTERA-2: 97.4;RPTEC TERT1: 91.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA004922, CAB011525, HPA031053" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB011525: AB_470302, HPA004922: AB_1846238, HPA031053: AB_2673713" "unprognostic (6.33e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-1)" "unprognostic (3.39e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-1)" "unprognostic (2.39e-1)" "unprognostic (6.64e-2)" "unprognostic (2.18e-2)" "unprognostic (2.17e-1)" "unprognostic (1.21e-2)" "unprognostic (9.06e-2)" "prognostic favorable (2.56e-5)" "unprognostic (2.16e-2)" "unprognostic (1.02e-1)" "unprognostic (9.38e-2)" "unprognostic (1.17e-1)" 0.3 0.3 4.1 6.2 3.0 4.0 27.7 2.7 3.5 44.9 2.0 30.7 12.4 6.0 4.3 5.1 5.4 30.9 6.7 3.3 2.8 20.9 1.8 3.1 0.0 3.8 4.3 0.1 14.4 0.0 0.1 30.1 3.6 2.8 16.7 272.9 57.9 7.1 1.0 0.9 22.9 3.5 2.8 0.2 24.8 8.0 5.0 0.1 4.8 0.0 0.1 4.2 0.2 3.1 0.0 0.0 37.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 70.6 28.9 0.6 62.2 0.0 0.0 0.1 7.3 0.0 0.1 0.3 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 97.4 0.0 0.0 1.4 0.1 0.0 91.1 0.1 12.0 3.6 0.0 2.4 1.9 3.5 0.6 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 3.0 2.7 3.5 3.3 2.8 3.8 4.3 3.6 2.8 5.0 3.1 0.2 3.2 4.8 1.3 0.3 0.0 0.1 7.2 0.0 14.8 38.2 30.0 8.6 31.5 29.9 82.8 581.7 0.6 1.0 39.3 0.0 64.1 31.4 71.1 1.7 5.1 44.4 2.1 0.9 15.5 0.1 4.4 31.6 14.8 0.0 3.8 0.7 0.1 0.1 10.1 5.4 15.0 34.6 0.0 0.0 44.3 3.1 0.7 0.0 27.2 0.6 47.5 0.0 45.8 1.2 38.2 28.3 6.4 0.4 1.5 18.8 3.6 144.8 311.3 0.0 0.8 3.1 2.1 1.0 0.7 0.0 0.1 0.7 0.3 26.0 4.1 PROSER1 "bA50D16.2, C13orf23, FLJ12661" ENSG00000120685 "Proline and serine rich 1" Q86XN7 13 39009865-39038089 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034225, HPA055687" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "CAB034225: AB_1564157, HPA055687: AB_2682886" "unprognostic (6.75e-3)" "unprognostic (9.56e-3)" "unprognostic (1.33e-1)" "unprognostic (3.81e-2)" "unprognostic (7.06e-2)" "unprognostic (2.92e-2)" "unprognostic (3.73e-3)" "unprognostic (5.98e-2)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" "unprognostic (3.60e-1)" "unprognostic (1.07e-1)" "unprognostic (2.93e-1)" "unprognostic (9.31e-3)" "unprognostic (2.33e-1)" "unprognostic (1.87e-1)" "unprognostic (1.95e-1)" 9.0 7.7 4.7 11.1 5.1 25.5 9.1 7.0 6.2 7.6 4.4 12.8 10.6 9.0 9.0 11.6 7.2 6.0 8.9 4.8 4.3 9.0 9.5 12.2 13.4 6.7 5.2 6.9 15.5 5.7 7.7 21.0 5.9 10.6 13.7 9.9 13.6 6.2 10.1 15.8 12.4 7.8 5.1 12.8 10.9 12.7 5.0 14.0 10.0 7.2 14.6 8.5 9.4 6.9 16.0 12.2 37.3 25.9 12.5 10.0 59.1 14.8 13.0 14.6 15.5 39.0 24.3 37.1 11.7 14.5 19.7 26.9 40.5 26.6 23.8 56.6 33.1 54.7 13.4 27.1 28.5 57.7 32.4 13.3 31.4 23.2 52.3 9.0 24.2 41.9 27.6 21.8 15.7 27.8 35.2 30.6 55.8 31.4 13.0 36.6 39.6 23.3 14.6 24.6 21.0 24.2 10.4 26.8 21.7 28.9 28.8 32.9 22.2 8.4 13.5 16.7 18.9 20.2 22.6 39.7 13.6 31.5 16.8 4.6 1.9 0.4 2.8 1.6 3.1 2.0 2.8 3.0 2.2 1.4 2.4 2.6 0.5 4.2 2.5 2.5 1.7 2.7 4.7 5.1 7.0 6.2 4.8 4.3 6.7 5.2 5.9 5.1 5.0 6.9 9.5 3.2 15.3 13.7 11.7 7.0 5.2 4.6 8.0 11.7 8.4 7.6 6.2 5.7 5.6 0.0 8.4 19.3 19.4 12.7 1.9 7.3 16.8 9.0 9.4 10.0 11.4 6.3 16.8 13.5 18.5 6.4 11.2 12.1 12.0 12.5 8.6 6.0 10.4 16.8 12.7 16.3 0.0 16.3 8.0 5.6 6.5 9.9 5.4 12.2 9.9 4.5 13.4 14.1 27.3 15.0 19.2 4.9 16.9 11.2 6.5 3.6 6.0 9.5 0.0 7.8 7.2 14.0 11.6 10.5 7.2 26.8 11.5 5.2 14.8 8.1 PRPF19 "hPSO4, NMP200, PRP19, PSO4, SNEV, UBOX4" ENSG00000110107 "Pre-mRNA processing factor 19" Q9UMS4 11 60890547-60906585 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012448, HPA038051, HPA059070" Supported Enhanced "Nuclear speckles" NA NA 71000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" "CAB012448: AB_2170868, HPA038051: AB_2675807, HPA059070: AB_2683896" "unprognostic (5.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (4.11e-8)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (9.37e-3)" "unprognostic (9.53e-2)" "unprognostic (1.54e-1)" "unprognostic (6.70e-2)" "unprognostic (9.62e-2)" "unprognostic (7.12e-2)" "unprognostic (9.04e-2)" "unprognostic (3.41e-3)" 46.1 70.6 89.8 49.8 87.9 67.0 48.8 73.7 100.2 57.4 60.2 54.5 42.9 55.4 34.2 81.7 57.3 29.4 47.9 91.3 94.1 50.4 77.2 34.6 64.1 92.0 80.7 66.6 69.4 79.8 79.3 42.9 92.9 62.1 51.8 46.1 56.5 48.2 75.2 80.3 49.5 47.9 75.6 54.3 54.3 30.5 81.1 78.5 43.4 38.9 73.7 58.7 55.9 84.5 197.5 147.0 161.8 116.2 92.7 80.8 155.6 102.4 137.5 200.2 149.0 162.7 141.1 280.5 145.2 98.2 120.2 179.0 229.2 184.6 153.4 207.0 153.4 232.4 111.3 184.9 134.2 308.6 161.1 86.3 137.0 154.4 171.9 58.7 158.7 167.4 248.2 155.3 99.5 270.6 328.9 249.5 292.6 150.5 197.7 285.8 165.5 227.5 101.7 127.5 142.3 172.9 126.6 208.3 178.0 73.1 225.8 170.2 101.9 89.6 147.2 161.8 171.2 147.2 223.3 287.9 111.6 208.6 138.6 4.2 7.8 2.0 2.4 3.8 1.7 0.9 1.8 1.7 3.6 2.4 2.2 2.0 0.5 1.8 2.3 3.9 1.7 1.0 89.8 87.9 73.7 100.2 91.3 94.1 92.0 80.7 92.9 75.6 81.1 84.5 15.8 19.2 23.7 10.1 26.7 42.1 35.2 40.2 33.0 32.0 24.6 19.4 17.6 20.0 28.6 27.6 10.4 94.7 16.2 20.4 27.4 48.5 21.6 21.4 19.7 27.3 39.0 45.2 19.8 51.6 90.2 24.9 23.4 28.4 22.8 25.4 20.0 46.1 46.3 62.2 22.2 40.0 32.6 23.0 21.6 3.6 37.0 19.3 26.6 11.2 41.2 25.4 21.6 10.1 11.8 33.4 27.7 38.7 31.9 40.4 27.8 27.9 17.8 25.3 46.0 22.4 22.6 25.2 38.0 37.4 41.6 40.6 24.8 24.8 55.1 26.3 PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155732-59206709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.1;lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 26.3;Extravillous trophoblasts: 22.3;Granulosa cells: 14.4;Kupffer cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA023923: AB_1855783, HPA052376: AB_2681803" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (1.90e-4)" "unprognostic (2.15e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (1.79e-4)" "unprognostic (7.22e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.80e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.84e-1)" "unprognostic (1.55e-3)" 1.3 0.7 1.8 6.5 2.0 18.1 1.8 4.3 2.7 1.2 1.1 4.6 6.5 1.7 0.5 3.8 1.4 1.4 1.0 2.0 1.3 0.6 1.4 2.3 10.3 2.3 1.5 1.4 0.5 0.3 0.0 4.3 2.2 0.8 5.6 1.7 0.6 0.7 1.2 3.1 5.0 3.6 1.1 3.3 2.4 1.8 2.3 20.6 1.3 0.4 12.0 2.0 0.6 3.7 105.3 56.9 84.5 24.8 2.4 16.0 31.7 66.7 41.9 69.1 54.2 68.4 78.7 80.2 65.9 52.7 56.2 40.7 67.0 73.9 145.0 99.3 39.1 86.4 58.8 50.3 0.6 88.7 32.5 4.0 5.3 81.9 109.0 17.1 77.2 57.9 48.6 76.7 72.8 95.2 80.7 26.1 31.9 52.0 82.5 67.3 135.7 45.9 20.0 32.4 34.5 45.4 61.7 18.4 29.2 38.0 54.4 34.1 57.8 146.4 157.3 73.5 117.8 48.8 108.2 73.6 34.5 47.4 150.1 1.7 2.1 2.3 0.6 4.0 0.2 1.1 0.5 0.7 2.6 0.6 0.3 0.5 2.1 0.5 9.5 1.1 1.4 0.8 1.8 2.0 4.3 2.7 2.0 1.3 2.3 1.5 2.2 1.1 2.3 3.7 4.5 0.0 1.7 3.3 3.1 1.9 2.0 1.5 0.0 2.0 0.8 1.5 2.0 1.5 1.6 0.0 0.0 6.2 1.4 2.0 0.0 0.4 0.9 1.4 1.9 3.6 4.9 26.3 1.6 0.5 22.3 2.9 2.6 2.2 2.5 14.4 4.2 0.3 7.8 1.7 1.8 5.0 0.0 18.6 6.3 0.4 0.9 7.8 1.8 2.8 8.4 0.9 4.1 2.0 3.4 0.9 0.7 2.2 9.7 1.1 0.5 0.5 0.6 3.2 0.0 2.9 3.3 2.6 5.1 5.5 1.3 2.1 3.3 1.3 8.4 1.7 PRR15L "ATAD4, MGC11242" ENSG00000167183 "Proline rich 15 like" Q9BU68 17 47951967-47957883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 178.4;pancreas: 103.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 203.0;Distal tubular cells: 170.2;Intestinal goblet cells: 127.8;Paneth cells: 226.4;Proximal enterocytes: 263.7;Undifferentiated cells: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 205.6" "Not detected" "Not detected" HPA022918 Approved Approved Cytosol No NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA022918: AB_2060743" "unprognostic (9.91e-2)" "unprognostic (4.77e-2)" "unprognostic (8.18e-2)" "unprognostic (5.75e-3)" "unprognostic (1.83e-1)" "unprognostic (2.31e-2)" "unprognostic (2.48e-1)" "unprognostic (5.22e-2)" "unprognostic (2.86e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (8.32e-2)" "prognostic favorable (6.29e-13)" "prognostic favorable (1.69e-5)" "unprognostic (1.36e-1)" "unprognostic (8.26e-2)" "unprognostic (3.34e-2)" 2.2 0.1 0.0 7.9 0.1 0.1 38.8 0.2 0.2 13.4 9.5 111.2 178.4 1.4 18.3 12.9 26.5 22.0 0.4 0.8 0.0 28.0 1.9 21.7 0.2 0.1 0.0 0.3 103.9 0.8 8.5 0.0 0.0 17.7 124.3 0.0 51.8 15.8 0.1 10.0 128.5 3.3 0.0 0.0 84.4 2.5 0.0 0.4 67.8 0.0 2.0 2.7 6.7 0.1 3.8 0.6 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 8.6 5.8 0.2 0.3 0.0 0.0 20.5 0.0 0.1 0.0 0.4 0.7 0.2 0.0 2.6 0.0 0.4 0.4 0.0 4.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 19.7 0.4 0.4 0.0 205.6 0.7 0.3 0.0 1.4 1.1 2.6 11.7 0.5 0.0 35.7 0.0 0.0 24.1 0.0 0.1 0.3 0.0 0.7 0.1 0.1 0.1 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 22.4 19.8 0.3 0.1 0.0 2.6 2.4 0.0 0.0 16.7 8.9 0.1 80.1 19.8 16.5 0.0 0.0 0.1 203.0 170.2 35.6 5.5 9.8 0.3 0.2 31.6 0.0 0.1 36.1 0.0 0.4 55.5 3.9 0.0 0.0 0.0 0.8 0.1 0.0 0.1 127.8 24.4 0.0 0.0 9.0 1.2 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 11.6 226.4 0.4 0.2 15.6 263.7 30.0 19.2 0.0 0.0 0.0 1.0 11.1 0.1 7.3 0.0 0.0 0.6 0.0 100.9 9.9 PRR4 "LPRP, PROL4" ENSG00000111215 "Proline rich 4" Q16378 12 10845849-10849475 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "salivary gland: 6616.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 92.8;Cone photoreceptor cells: 139.7;Horizontal cells: 85.8;Rod photoreceptor cells: 119.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "OE19: 2.8" HPA042133 Supported "Secreted to digestive system" NA NA 14000000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA042133: AB_10793979" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.35e-2)" "unprognostic (1.74e-2)" "unprognostic (1.99e-1)" "unprognostic (5.03e-2)" "unprognostic (3.01e-3)" "unprognostic (3.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.23e-1)" "unprognostic (3.19e-2)" "unprognostic (1.09e-2)" "unprognostic (3.57e-6)" "unprognostic (2.81e-2)" "unprognostic (9.15e-2)" "unprognostic (1.21e-1)" "unprognostic (2.15e-2)" 1.9 2.0 0.6 0.0 0.6 0.1 9.7 0.6 1.8 0.1 0.6 0.2 7.6 0.0 0.0 148.1 0.0 0.0 0.4 0.6 0.6 0.2 0.2 74.4 0.0 0.8 0.6 0.1 2.7 0.0 2.0 0.1 0.6 4.0 0.0 0.0 6616.8 0.1 0.8 73.4 0.2 0.0 0.6 0.1 66.0 0.5 0.6 0.0 0.1 0.0 0.5 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 2.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 1.8 0.6 0.6 0.8 0.6 0.6 0.6 0.6 0.6 0.3 3.2 0.0 0.0 22.0 3.1 6.8 19.9 9.6 92.8 7.5 2.8 1.8 7.2 8.2 1.8 139.7 16.4 20.1 6.3 1.9 0.1 10.2 0.1 0.2 9.6 16.2 14.1 0.0 0.4 2.5 9.3 10.7 0.1 8.9 0.4 14.6 5.9 7.7 85.8 0.0 6.4 24.4 8.7 6.0 13.9 21.8 6.1 28.4 0.0 7.9 18.2 56.7 0.0 0.0 3.4 14.4 24.5 17.1 9.3 7.9 0.2 6.8 119.2 13.1 23.0 7.1 13.5 5.7 8.1 2.3 4.0 20.1 0.5 9.6 4.0 PRRG1 PRGP1 ENSG00000130962 "Proline rich and Gla domain 1" O14668 X 37349309-37457292 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078129 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" Nucleoplasm "HPA078129: AB_2686878" "unprognostic (8.82e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (8.34e-2)" "unprognostic (2.08e-3)" "unprognostic (1.92e-1)" "unprognostic (5.11e-3)" "unprognostic (2.24e-2)" "unprognostic (7.23e-3)" "unprognostic (1.01e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (8.21e-2)" "prognostic favorable (2.05e-7)" "unprognostic (1.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" 8.6 3.7 12.3 2.1 24.9 0.2 5.2 21.6 19.7 4.4 4.7 4.0 2.9 4.3 1.5 4.1 2.6 8.8 6.4 12.9 15.9 10.5 7.9 5.5 1.7 26.7 21.3 4.2 1.6 1.2 1.4 8.1 25.3 3.4 4.1 1.5 2.9 7.8 15.9 2.2 3.0 5.4 18.4 2.9 2.4 1.5 18.4 1.5 8.3 7.8 1.0 5.6 3.8 39.4 32.3 7.2 5.6 5.6 18.7 15.4 2.4 14.1 17.6 4.7 8.2 17.1 20.2 0.0 21.8 10.4 8.9 10.7 15.6 10.0 8.3 0.1 5.2 5.2 7.7 5.7 22.6 0.0 7.2 23.2 8.1 9.1 7.7 9.4 24.8 0.0 2.6 0.1 16.5 2.4 0.1 0.1 6.8 5.1 13.4 0.0 13.1 0.0 79.2 1.7 0.0 0.1 9.7 15.6 6.1 15.3 0.1 3.5 17.6 7.5 4.2 14.2 4.1 0.0 0.1 0.0 7.3 0.0 7.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.3 24.9 21.6 19.7 12.9 15.9 26.7 21.3 25.3 18.4 18.4 39.4 29.7 6.4 4.2 15.7 0.0 11.3 4.8 7.6 5.2 2.2 5.3 5.3 8.1 15.7 2.7 33.1 0.0 7.0 0.2 7.6 7.9 6.8 0.7 3.3 12.9 18.4 3.0 0.0 23.3 3.1 14.9 9.6 4.6 9.2 1.3 3.9 17.9 16.3 4.8 18.5 10.8 5.7 14.2 4.1 5.3 0.4 4.7 1.4 3.6 31.9 0.8 2.2 0.0 12.5 229.8 18.7 7.5 2.6 0.0 9.1 4.3 9.4 2.9 0.5 6.6 8.3 8.4 2.5 4.2 5.2 6.3 10.4 0.4 3.5 4.8 8.1 PRSS16 TSSP ENSG00000112812 "Serine protease 16" Q9NQE7 6 27247701-27256624 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 58 "lymphoid tissue: 826.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 42.1;Extravillous trophoblasts: 25.4;Syncytiotrophoblasts: 31.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.1" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Cell line enhanced" "Detected in many" "hTCEpi: 20.4;RPMI-8226: 11.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.50e-1)" "unprognostic (6.95e-2)" "unprognostic (1.91e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.74e-2)" "unprognostic (9.21e-3)" "unprognostic (1.57e-1)" "unprognostic (7.89e-2)" "prognostic favorable (6.46e-5)" "unprognostic (1.57e-1)" "unprognostic (3.49e-2)" "unprognostic (5.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.62e-2)" 0.2 0.4 0.0 0.3 0.0 0.0 6.0 0.1 0.3 3.6 0.0 5.7 4.4 0.7 13.5 2.9 5.6 4.0 0.0 0.1 0.0 1.8 0.0 3.8 0.1 0.0 0.0 2.5 14.1 7.8 1.4 4.1 0.1 3.2 6.7 0.1 7.5 4.2 0.0 5.1 3.3 0.2 0.0 0.3 4.8 1.0 0.0 826.7 13.1 0.0 1.4 2.5 1.0 0.0 3.2 0.2 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.1 3.8 4.7 0.0 0.7 0.0 0.0 1.5 2.7 3.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 2.1 0.5 0.0 20.4 0.0 4.1 0.5 0.0 1.7 2.5 1.9 0.0 1.2 0.5 0.0 0.7 2.1 0.5 0.0 0.0 11.5 2.4 3.6 0.0 0.0 1.4 3.2 0.0 4.5 2.0 0.9 0.0 0.0 0.7 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.7 2.1 0.9 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 9.6 7.7 0.0 2.6 6.4 10.8 4.6 8.6 0.0 16.6 9.5 0.4 15.7 4.6 14.7 0.0 42.1 0.2 22.9 1.9 10.0 0.6 2.5 0.8 0.4 4.2 0.0 0.7 17.6 25.4 0.7 12.8 8.0 5.7 0.1 0.0 0.0 4.0 0.0 0.2 20.0 14.2 0.3 0.4 0.5 0.6 0.3 5.4 0.0 0.2 1.2 0.0 0.0 0.1 9.4 18.7 0.0 13.7 6.9 16.5 0.7 3.4 0.0 0.0 0.0 1.2 2.0 6.1 8.6 6.5 31.7 1.1 0.0 14.9 8.5 PRSS8 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 245.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 403.5;Extravillous trophoblasts: 648.4;Paneth cells: 262.6;Proximal enterocytes: 358.0;Syncytiotrophoblasts: 450.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 243.7;CACO-2: 165.9;CAPAN-2: 111.9;hTCEpi: 157.8;OE19: 79.6;SK-BR-3: 186.3" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in single" HPA030436 Uncertain "Secreted - unknown location" NA NA 4400000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" 0.8 0.4 0.3 15.0 0.4 0.2 25.5 2.1 0.6 31.1 6.7 129.4 155.7 9.9 113.0 136.2 15.4 47.7 0.4 0.6 0.2 90.6 28.0 54.1 0.3 0.3 0.2 0.6 139.4 56.0 8.4 51.0 0.4 49.0 72.6 0.0 245.4 8.5 0.3 115.3 151.8 3.5 0.1 0.2 156.2 0.5 0.2 15.4 50.8 0.0 11.8 4.9 56.0 0.2 63.4 0.2 0.1 0.2 0.0 0.0 243.7 0.0 0.0 0.0 0.0 165.9 111.9 0.0 1.3 0.0 0.0 73.5 0.1 69.7 0.0 0.3 0.4 0.1 0.3 6.5 0.0 0.0 0.3 0.0 157.8 0.0 2.4 0.0 0.0 0.1 1.9 0.1 0.0 68.1 0.6 1.4 20.5 79.6 0.1 0.5 0.0 1.2 7.5 13.1 0.9 0.7 0.0 186.3 0.1 18.8 42.8 0.8 0.0 0.1 1.9 0.6 0.4 0.3 0.5 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.1 0.6 0.6 0.2 0.3 0.2 0.4 0.1 0.2 0.2 0.4 99.3 60.1 0.0 1.0 37.9 82.7 108.9 76.2 0.5 74.4 39.2 0.3 62.9 107.4 42.3 0.0 168.8 0.8 403.5 29.4 192.4 0.0 35.2 11.4 2.6 9.6 2.7 0.1 224.4 648.4 3.5 82.6 109.5 7.0 0.0 0.0 18.2 22.8 0.0 0.2 132.1 87.5 0.3 2.7 0.0 0.6 1.9 3.6 0.0 4.2 0.3 0.0 0.0 0.0 240.7 262.6 0.0 0.1 66.0 358.0 28.6 21.2 0.1 0.0 0.1 4.7 0.0 0.2 81.9 54.0 450.7 2.2 0.0 150.8 91.0 PRXL2A "Adrx, C10orf58, FAM213A, MGC4248, PAMM" ENSG00000122378 "Peroxiredoxin like 2A" Q9BRX8 10 80407829-80437115 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Antioxidant "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 405.6" "Group enriched" "Detected in some" 7 "Adipocytes: 161.4;Cardiomyocytes: 161.5;Hofbauer cells: 75.1;Smooth muscle cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 166.0" "Lineage enriched" "Detected in all" 11 "dendritic cells: 166.0" "Cell line enhanced" "Detected in many" "ASC diff: 947.9;HaCaT: 276.4;HUVEC TERT2: 436.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009025, HPA024565" Enhanced "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA009025: AB_1078312, HPA024565: AB_1845519" "unprognostic (1.73e-2)" "unprognostic (2.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-2)" "unprognostic (3.14e-1)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (7.01e-2)" "unprognostic (3.54e-2)" "unprognostic (2.83e-3)" "unprognostic (3.32e-3)" "unprognostic (3.55e-1)" "unprognostic (6.78e-2)" "unprognostic (1.80e-1)" "prognostic favorable (6.11e-4)" 405.6 25.1 112.4 15.9 110.4 3.6 210.2 97.4 119.8 92.0 122.6 51.8 84.0 52.5 212.8 83.9 30.9 30.8 76.3 121.8 104.3 110.9 197.3 20.9 18.0 108.2 111.3 30.7 66.0 69.0 59.1 45.2 108.5 70.4 43.2 42.9 50.6 44.3 49.7 81.1 59.8 19.9 103.1 12.3 24.8 51.5 131.1 34.7 55.1 75.8 26.9 71.4 51.9 101.5 26.0 62.9 105.3 0.4 947.9 0.1 7.2 4.0 22.0 2.0 0.5 60.1 76.3 16.6 82.1 0.3 47.1 276.4 9.5 10.9 0.5 1.1 17.6 32.5 23.8 89.0 91.9 0.3 9.0 71.1 20.2 6.7 0.3 250.1 436.7 95.1 26.9 0.6 0.0 89.6 41.9 4.7 51.2 39.1 0.3 117.5 48.5 0.8 223.1 106.2 107.6 76.6 11.0 147.7 168.4 78.9 66.2 46.2 119.1 0.6 1.0 0.5 0.6 9.3 22.0 0.4 66.0 0.6 7.6 1.3 3.5 11.6 6.6 0.8 5.1 15.8 3.7 5.5 3.3 11.1 13.4 13.9 2.2 6.2 0.2 166.0 0.2 4.8 112.4 110.4 97.4 119.8 121.8 104.3 108.2 111.3 108.5 103.1 131.1 101.5 161.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.5 0.0 0.0 0.0 0.0 13.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 7.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.6 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 0.0 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PSAPL1 ENSG00000178597 "Prosaposin like 1" Q6NUJ1 4 7430285-7434930 "Predicted secreted proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 98.5;stomach 1: 38.6" "Cell type enriched" "Detected in some" 13 "Gastric mucus-secreting cells: 41.8" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.7;melanoma: 2.5;pancreatic cancer: 2.0;stomach cancer: 3.0;urothelial cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CACO-2: 16.6;OE19: 32.2;RPMI-8226: 24.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038013, HPA038482" Approved Enhanced Cytosol "Secreted - unknown location" NA NA 31000 "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA038013: AB_10673652, HPA038482: AB_2676037" "unprognostic (2.64e-2)" "unprognostic (2.40e-1)" "unprognostic (9.33e-2)" "unprognostic (2.40e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-3)" "unprognostic (2.52e-1)" "unprognostic (2.08e-2)" "unprognostic (2.75e-1)" "unprognostic (2.63e-3)" 0.3 0.0 0.0 0.0 0.3 0.0 4.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 98.5 0.0 0.0 0.0 0.0 38.6 3.4 0.1 0.2 0.0 0.0 3.1 0.0 0.2 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.0 0.0 0.0 24.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.2 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 PSAT1 PSA ENSG00000135069 "Phosphoserine aminotransferase 1" Q9Y617 9 78297125-78330093 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 175.0;liver: 267.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 115.5;Glandular and luminal cells: 145.9;Hepatocytes: 161.7;Proximal tubular cells: 304.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 15.1" "Lineage enriched" "Detected in many" 5 "T-cells: 15.1" "Cell line enhanced" "Detected in many" "hTCEpi: 1170.1;SK-MEL-30: 752.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014882, CAB040567, HPA042924" Enhanced Enhanced Cytosol NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "CAB014882: , CAB040567: , HPA042924: AB_2678223" "unprognostic (8.26e-3)" "unprognostic (4.69e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (5.62e-5)" "unprognostic (4.05e-3)" "unprognostic (1.41e-1)" "unprognostic (2.21e-3)" "unprognostic (1.86e-1)" "unprognostic (9.85e-2)" "unprognostic (2.25e-2)" "unprognostic (4.53e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.87e-3)" "unprognostic (1.21e-1)" "unprognostic (8.07e-3)" "unprognostic (1.71e-1)" 7.8 65.8 123.3 7.3 124.6 2.0 5.1 130.5 175.0 5.1 92.8 5.9 5.4 4.3 61.6 33.2 34.7 1.7 2.7 122.4 126.5 136.7 267.9 5.1 9.3 130.2 122.4 5.6 129.1 9.7 7.6 3.0 129.9 10.0 5.5 6.2 19.2 4.0 0.6 57.2 4.5 3.3 133.6 6.0 19.4 10.4 120.3 30.0 30.3 0.5 12.4 7.3 11.2 161.6 222.8 146.0 121.1 215.6 35.1 41.2 284.7 184.3 130.4 91.8 170.6 38.2 41.9 143.2 79.8 416.9 82.9 215.3 209.1 203.6 136.4 141.2 73.9 49.2 60.8 293.3 322.0 277.6 84.6 131.1 1170.1 122.0 322.9 22.6 85.0 548.3 53.8 358.2 77.1 83.2 95.8 44.3 278.2 415.1 158.4 46.5 78.6 173.4 126.6 50.9 54.9 127.0 51.1 87.7 752.3 75.9 42.0 344.1 19.9 23.2 73.5 85.9 151.5 242.0 242.7 0.8 268.9 215.6 112.1 0.0 0.0 0.0 5.2 0.0 5.9 3.1 5.0 7.0 0.3 1.3 8.1 7.5 0.3 0.0 0.1 0.0 15.1 3.3 123.3 124.6 130.5 175.0 122.4 126.5 130.2 122.4 129.9 133.6 120.3 161.6 0.4 0.0 0.0 70.2 11.0 41.9 8.8 18.9 115.5 0.9 1.8 3.9 0.6 1.5 4.7 11.0 0.0 32.0 2.2 2.0 62.6 11.5 1.7 77.7 10.3 3.7 3.6 29.9 7.3 48.4 13.7 4.2 6.6 145.9 0.0 0.5 3.6 161.7 5.3 5.0 6.0 4.8 18.3 4.4 2.9 3.8 5.0 3.4 19.6 5.6 3.8 26.7 0.0 48.2 78.8 22.7 0.1 1.9 29.1 16.0 0.3 304.1 3.8 1.1 0.0 33.5 14.3 1.6 3.7 35.5 50.7 9.3 8.6 68.2 4.2 11.8 PSCA ENSG00000167653 "Prostate stem cell antigen" O43653 8 142670308-142682725 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 3019.3" "Cell type enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 5332.3" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 785.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 22.4;HeLa: 45.7;OE19: 17.6;RT4: 61.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "spinal cord: 38.2" "HPA030783, HPA056418" Approved Supported "Plasma membrane" NA NA 18000 "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA030783: AB_2673611, HPA056418: AB_2683123" "unprognostic (1.21e-3)" "unprognostic (1.76e-3)" "unprognostic (3.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.77e-2)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.81e-3)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (6.82e-2)" "unprognostic (2.38e-3)" "unprognostic (4.93e-2)" "unprognostic (2.68e-1)" "unprognostic (3.07e-1)" "unprognostic (1.06e-3)" 4.8 0.4 0.5 0.5 0.6 0.2 1.9 0.3 0.9 67.8 0.2 7.8 4.0 0.4 0.6 334.0 7.9 10.0 0.4 0.6 0.2 5.8 0.7 6.3 0.1 0.5 0.3 0.6 3.2 0.0 0.6 2.4 0.4 230.6 4.8 0.0 23.5 1.9 0.3 11.1 2.5 0.1 0.2 0.4 3019.3 1.4 0.5 0.4 0.4 0.0 15.0 629.0 167.7 0.5 10.7 0.7 0.0 0.0 2.1 6.8 10.6 4.9 1.1 2.1 1.8 0.1 22.4 0.0 0.4 0.4 8.1 2.1 0.0 0.4 1.3 0.6 0.0 0.0 45.7 0.0 0.1 0.0 1.5 6.0 7.8 4.6 0.0 0.6 0.0 0.0 0.0 0.0 1.7 5.8 1.7 0.6 1.2 17.6 1.2 0.7 0.0 0.9 1.0 61.7 0.2 0.5 5.1 15.6 3.5 0.3 0.2 0.2 1.0 1.5 1.7 2.7 0.0 1.9 0.1 0.0 2.9 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.3 0.9 0.6 0.2 0.5 0.3 0.4 0.2 0.5 0.5 0.2 3.2 1.5 1.6 7.7 0.9 26.0 120.0 0.0 0.0 3.9 2.7 1.2 71.4 894.2 1.8 0.0 2.3 0.0 1.9 7.9 3.2 0.3 1.3 0.1 1.1 275.1 0.0 0.3 1.2 5.0 3.3 5332.3 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.2 12.9 179.0 0.6 1.0 0.4 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 57.1 0.2 0.0 13.4 238.7 0.3 0.4 994.9 0.0 0.0 0.0 48.9 0.0 0.5 13.1 1.3 28.5 4.6 0.0 0.9 1241.5 PSG7 ENSG00000221878 "Pregnancy specific beta-1-glycoprotein 7" Q13046 19 42924132-42937207 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "placenta: 4.1;skin 1: 1.2" "Cell type enriched" "Detected in some" 95 "Syncytiotrophoblasts: 162.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.6;fHDF/TERT166: 1.1;HBF TERT88: 2.3;U-2197: 1.8" HPA046327 Supported "Secreted in female reproductive system" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046327: AB_2679624" 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 162.0 0.0 0.0 0.0 0.0 PSRC1 DDA3 ENSG00000134222 "Proline and serine rich coiled-coil 1" Q6PGN9 1 109279556-109283186 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 101.5;choroid plexus: 47.9;retina: 41.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 30.1;Oligodendrocytes: 95.2;Peritubular cells: 44.8;Rod photoreceptor cells: 71.0" "Cancer enriched" "Detected in all" 4 "glioma: 50.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 12.0" "Group enriched" "Detected in many" 11 "dendritic cells: 5.4;granulocytes: 7.1;monocytes: 12.0" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 3.5;cerebral cortex: 7.7;hippocampal formation: 5.7;white matter: 3.4" "Low region specificity" "Detected in all" HPA056561 Supported Nucleoplasm,Cytosol NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Nucleoplasm "HPA056561: AB_2683175" "unprognostic (1.14e-1)" "unprognostic (1.65e-1)" "unprognostic (1.42e-3)" "unprognostic (6.78e-3)" "unprognostic (2.17e-1)" "unprognostic (4.76e-2)" "prognostic unfavorable (1.36e-9)" "unprognostic (3.51e-2)" "unprognostic (6.21e-2)" "unprognostic (4.88e-3)" "unprognostic (1.76e-2)" "unprognostic (1.92e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.43e-2)" "unprognostic (2.08e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" 2.0 1.9 64.7 3.8 84.0 7.9 2.4 76.5 84.1 5.1 47.9 3.9 4.3 3.1 2.6 7.6 3.5 3.0 3.0 69.7 71.2 2.7 4.5 5.3 3.6 78.0 79.9 3.3 1.5 3.2 4.2 4.0 83.0 5.5 2.7 41.6 2.4 4.5 0.9 5.2 4.5 3.9 67.9 3.9 3.4 13.3 74.1 14.2 2.3 0.9 4.3 3.2 5.8 101.5 56.0 28.2 112.9 55.1 4.4 8.7 31.0 43.1 34.7 57.6 55.1 43.7 22.7 28.2 15.4 21.4 27.1 38.9 61.4 35.4 48.1 11.0 29.6 17.7 40.5 36.2 5.0 19.0 19.3 10.0 3.3 22.8 16.2 21.5 28.7 32.9 40.9 12.5 46.8 50.5 29.2 12.9 46.9 25.4 31.8 44.4 108.7 9.5 19.6 14.4 47.2 27.3 24.3 36.8 43.6 40.8 22.3 18.0 14.9 35.4 57.9 25.1 72.5 9.7 6.9 9.8 28.6 44.9 100.9 0.0 12.0 1.9 0.6 4.8 0.4 0.0 0.7 0.2 5.4 0.0 0.4 0.3 7.1 0.3 2.7 0.0 0.7 3.4 64.7 84.0 76.5 84.1 69.7 71.2 78.0 79.9 83.0 67.9 74.1 101.5 0.7 0.0 3.9 9.8 0.5 2.0 1.8 2.3 0.6 6.7 2.1 5.6 1.3 1.5 0.5 1.8 25.0 17.6 1.0 2.0 0.0 0.9 1.1 0.5 3.2 2.3 0.0 0.8 19.3 0.9 30.1 4.4 0.5 1.1 1.3 12.9 2.9 1.2 10.9 3.3 3.8 3.9 4.1 4.4 1.8 2.6 5.9 4.9 1.8 2.8 2.2 10.0 0.0 18.1 95.2 0.5 0.6 44.8 0.6 1.0 0.6 2.9 0.9 71.0 0.0 5.5 4.7 5.0 1.5 6.5 1.1 2.9 1.5 1.1 5.4 1.3 PTGER3 "EP3, lnc003875" ENSG00000050628 "Prostaglandin E receptor 3" P43115 1 70852353-71047808 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 95.2;kidney: 81.2;smooth muscle: 68.0" "Group enriched" "Detected in many" 7 "Distal tubular cells: 225.0;Langerhans cells: 79.8" "Group enriched" "Detected in some" 7 "breast cancer: 4.1;renal cancer: 9.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 59 "basophil: 43.3" "Lineage enriched" "Detected in single" 59 "granulocytes: 43.3" "Cell line enhanced" "Detected in some" "ASC diff: 28.6;HAP1: 20.9;HDLM-2: 32.8;HEL: 15.6;T-47d: 72.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010689 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "HPA010689: AB_1855883" "unprognostic (1.53e-3)" "unprognostic (3.48e-1)" "unprognostic (1.11e-1)" "unprognostic (3.86e-3)" "unprognostic (1.47e-1)" "unprognostic (3.37e-2)" "unprognostic (4.80e-2)" "unprognostic (2.01e-2)" "unprognostic (1.24e-1)" "unprognostic (4.64e-3)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (8.83e-3)" "unprognostic (1.86e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-4)" 54.5 6.7 7.1 5.0 4.3 0.2 28.6 0.0 8.5 4.7 10.4 13.9 1.2 95.2 3.7 3.9 10.1 8.9 1.6 4.7 10.9 81.2 0.3 1.0 1.3 5.6 0.6 1.7 6.6 0.9 0.6 0.6 3.2 3.0 2.3 0.7 11.9 7.9 0.4 13.8 3.7 68.0 2.4 0.3 22.4 1.0 4.7 0.9 1.0 1.4 1.4 6.6 6.1 1.1 0.0 0.0 0.0 0.0 28.6 0.7 0.1 0.7 0.0 0.1 0.7 0.0 0.0 0.0 0.0 3.5 0.0 0.0 20.9 0.0 0.1 32.8 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.1 0.0 0.3 0.0 0.2 72.5 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.1 7.2 0.0 43.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 7.1 4.3 0.0 8.5 4.7 10.9 5.6 0.6 3.2 2.4 4.7 1.1 6.9 0.0 0.5 0.0 0.0 5.0 0.2 0.0 0.0 1.6 13.7 6.1 1.8 1.5 0.0 20.2 0.0 0.0 0.2 0.4 225.0 3.0 1.6 0.6 4.6 1.7 2.4 0.0 2.2 0.0 2.4 12.2 1.5 1.2 9.5 0.0 0.7 0.0 0.1 3.3 3.4 1.0 12.2 0.0 79.8 1.0 1.2 3.2 8.8 0.0 0.6 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.1 1.3 0.1 7.2 0.0 0.2 6.6 0.5 11.7 0.1 0.1 0.1 7.5 0.1 1.2 6.2 0.0 0.2 PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 108.3;skin 1: 152.5;urinary bladder: 175.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.9;Glandular and luminal cells: 191.9;granulocytes: 208.0;Hepatic stellate cells: 61.8;Macrophages: 55.3;Suprabasal keratinocytes: 58.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 28.9" "Group enriched" "Detected in many" 6 "dendritic cells: 20.0;granulocytes: 28.9;monocytes: 13.1" "Cell line enhanced" "Detected in many" "ASC diff: 113.7;ASC TERT1: 89.5;BJ: 115.2;BJ hTERT+: 156.0;HEL: 73.6;HMC-1: 298.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002834, CAB020315" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "CAB020315: , HPA002834: AB_1079711" "unprognostic (4.20e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (5.88e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-3)" "unprognostic (3.32e-1)" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (4.03e-2)" "unprognostic (1.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.35e-4)" 12.8 2.9 3.1 10.5 3.2 9.0 6.7 4.2 4.8 5.8 5.5 108.3 10.8 6.1 2.2 67.3 43.2 9.6 12.6 7.4 5.5 9.3 3.0 11.3 4.6 6.5 5.2 2.0 1.8 2.0 4.8 2.2 6.3 21.1 24.2 0.7 4.3 6.1 2.1 152.5 17.7 16.1 6.7 8.0 20.5 0.9 7.0 2.2 3.2 4.0 11.6 175.0 15.9 11.9 0.3 0.5 0.4 0.0 113.7 89.5 0.0 115.2 156.0 1.0 1.1 0.0 0.2 4.2 5.4 19.7 0.3 7.1 0.4 10.5 0.9 0.0 0.2 73.6 0.6 0.0 32.9 5.2 298.4 46.1 1.2 5.7 0.3 0.0 42.3 0.1 0.1 0.3 2.3 0.0 0.2 6.6 1.6 0.0 0.5 0.3 1.4 8.6 14.7 0.0 0.5 0.6 0.6 9.5 0.2 0.5 0.3 8.4 1.0 0.7 0.6 1.7 0.1 0.3 0.2 0.0 0.4 31.6 0.3 28.9 12.1 23.3 0.0 13.1 0.0 2.4 0.0 0.0 20.0 3.5 0.1 0.0 5.2 2.8 10.2 1.4 0.2 21.9 3.1 3.2 4.2 4.8 7.4 5.5 6.5 5.2 6.3 6.7 7.0 11.9 0.9 0.0 6.6 0.0 5.9 9.9 2.6 7.7 0.0 0.1 1.1 1.4 1.6 4.3 2.2 42.3 0.0 0.1 0.2 0.1 0.0 0.6 0.1 109.9 10.4 24.7 1.8 18.7 0.8 0.5 0.3 10.7 2.0 191.9 208.0 0.1 61.8 0.8 26.1 0.0 0.5 0.6 4.1 15.5 20.7 0.3 1.5 55.3 3.6 16.9 11.7 0.0 7.2 1.0 0.1 0.6 0.6 0.0 0.3 2.8 0.0 0.0 0.8 0.1 0.0 1.4 3.6 0.0 0.2 18.2 58.7 0.4 3.4 0.1 1.0 0.8 PTH2R PTHR2 ENSG00000144407 "Parathyroid hormone 2 receptor" P49190 2 208359714-208854503 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 16.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 12.5;Distal tubular cells: 7.9;Excitatory neurons: 15.9;Proximal tubular cells: 16.1;Rod photoreceptor cells: 26.5" "Cancer enhanced" "Detected in many" "renal cancer: 6.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "EFO-21: 10.7;HEL: 16.0;HL-60: 4.0;SH-SY5Y: 6.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA010655 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA010655: AB_2668333" "unprognostic (4.76e-3)" "unprognostic (1.39e-3)" "unprognostic (1.64e-1)" "unprognostic (5.78e-2)" "unprognostic (3.77e-1)" "unprognostic (8.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (3.45e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-1)" "unprognostic (1.09e-3)" "unprognostic (2.54e-3)" "unprognostic (6.87e-2)" "unprognostic (1.30e-2)" "unprognostic (1.37e-2)" 1.2 0.3 2.2 0.1 1.1 4.2 0.9 0.0 3.1 0.0 0.1 0.0 0.0 0.7 2.1 0.0 0.0 0.0 0.0 2.4 2.0 0.2 0.6 0.1 0.1 0.3 0.6 0.0 0.6 0.0 0.3 1.2 0.2 0.5 0.0 16.5 3.6 0.5 0.0 0.1 0.0 0.5 0.1 0.1 0.0 0.5 4.5 0.0 0.0 0.0 0.1 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 2.2 1.1 0.0 3.1 2.4 2.0 0.3 0.6 0.2 0.1 4.5 1.5 0.1 0.0 0.0 0.3 0.6 0.0 0.0 0.1 0.0 1.1 1.8 3.2 0.2 0.0 0.1 5.5 12.5 0.5 0.9 0.0 7.9 0.1 0.6 0.2 0.5 0.1 1.8 4.2 15.9 0.0 0.1 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 1.0 0.1 2.5 2.1 2.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 26.5 0.0 0.0 0.4 0.6 0.4 0.0 0.0 0.1 0.1 0.3 0.0 0.0 PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 254.0;Basal squamous epithelial cells: 93.9;Breast glandular cells: 105.4;Breast myoepithelial cells: 56.3;Club cells: 77.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HaCaT: 291.3;HBEC3-KT: 359.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" 3.1 0.8 1.8 1.2 2.3 0.0 20.1 0.6 3.2 13.6 10.2 3.3 2.3 10.7 1.1 16.2 1.5 7.5 4.2 4.1 3.2 0.4 0.2 1.2 1.1 4.0 8.1 1.8 1.7 22.8 2.9 3.0 0.4 5.2 1.6 0.2 8.5 2.4 0.7 2.0 1.6 3.0 0.2 3.6 1.8 1.3 8.6 0.4 1.8 1.7 1.0 9.2 15.2 0.8 1.7 9.9 0.0 0.0 2.9 2.8 0.1 0.3 1.0 0.5 1.3 0.3 7.9 0.0 0.5 2.6 9.1 291.3 1.3 359.8 0.1 7.4 1.7 0.5 1.8 0.1 0.8 0.1 0.4 0.2 19.7 9.1 34.4 0.9 11.2 0.1 0.0 0.4 0.2 0.1 0.1 0.0 1.4 0.4 16.7 0.1 1.5 0.6 34.3 0.3 0.2 0.1 16.4 0.1 2.1 11.5 0.5 0.1 5.6 1.6 8.9 5.1 77.8 4.7 0.1 12.1 7.5 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.8 2.3 0.6 3.2 4.1 3.2 4.0 8.1 0.4 0.2 8.6 0.8 1.4 0.0 0.0 0.7 0.4 4.6 1.9 254.0 93.9 0.3 105.4 56.3 0.4 0.0 77.5 0.0 0.0 0.0 0.5 0.0 0.0 3.5 5.9 0.9 4.7 4.5 0.0 0.0 0.6 8.9 0.0 13.6 0.0 0.8 0.0 2.6 0.4 0.2 0.0 0.0 11.2 0.0 4.1 0.3 1.3 2.7 0.9 0.6 23.2 1.0 0.6 1.8 0.0 0.0 0.2 8.6 0.0 0.0 6.2 0.5 0.0 0.3 14.8 0.5 6.6 8.0 6.7 3.6 0.2 7.9 1.4 0.0 0.5 0.2 0.0 0.2 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 295.2;Excitatory neurons: 584.9;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 791.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA Yes 25000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 51.0 40.4 83.8 19.5 115.1 6.7 42.1 62.4 99.9 40.3 51.0 37.2 25.8 37.3 49.7 25.6 34.0 32.1 36.9 84.5 77.3 42.6 30.1 39.4 25.3 79.1 87.6 33.7 32.1 53.1 21.3 74.2 81.0 34.0 35.3 35.5 39.9 41.6 38.7 29.6 29.5 37.6 67.6 22.8 32.8 38.9 86.7 11.9 38.7 39.4 25.8 43.9 34.0 154.5 52.6 81.9 111.0 40.3 45.8 48.8 71.6 50.8 70.0 46.3 45.3 35.9 42.1 31.7 111.7 65.3 65.0 60.3 66.1 116.0 69.6 0.3 30.8 70.1 44.3 50.0 62.5 0.1 31.8 33.4 55.8 58.0 81.0 121.5 139.0 44.0 72.0 0.8 62.9 91.0 0.9 0.7 43.2 113.2 90.3 46.8 60.9 1.5 97.7 117.3 43.9 54.8 79.0 25.0 52.0 97.2 59.2 1.2 84.9 45.2 85.5 54.0 58.1 0.0 0.6 3.4 58.7 0.6 62.9 1.6 3.3 0.0 0.2 1.4 0.0 5.3 0.6 0.0 4.5 6.3 4.4 1.6 1.3 4.7 0.8 6.1 0.2 3.9 83.8 115.1 62.4 99.9 84.5 77.3 79.1 87.6 81.0 67.6 86.7 154.5 71.3 32.1 33.1 295.2 20.6 33.3 70.1 36.3 64.9 55.2 29.3 23.5 29.6 32.9 32.1 55.2 60.5 37.0 8.0 23.1 23.5 27.2 68.4 29.3 43.3 54.3 25.8 8.4 584.9 23.3 53.7 37.2 37.8 46.5 9.5 84.7 37.5 15.7 8.1 67.3 263.6 23.0 30.5 15.2 15.9 38.8 23.9 19.4 24.9 159.3 3.9 40.9 0.0 353.9 791.4 43.1 23.5 21.8 1.7 82.4 29.3 25.6 33.7 55.0 98.6 32.7 128.4 88.9 65.5 42.8 25.9 33.2 3.4 67.0 24.1 87.3 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.5 0.1 0.6 3.6 1.7 0.8 3.8 2.9 1.7 19.8 0.0 26.5 28.9 0.4 0.1 109.4 0.4 3.5 0.2 0.6 0.9 0.8 5.2 2.6 0.6 1.6 1.0 0.3 3.6 0.0 0.2 0.3 1.7 3.1 15.7 0.8 19.1 0.6 0.6 53.9 22.2 0.8 0.6 0.8 26.2 0.3 1.1 0.3 0.2 0.0 6.4 9.8 43.2 5.4 22.1 2.6 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 41.4 0.1 7.2 0.0 0.1 33.9 0.0 0.1 0.0 5.4 0.4 0.0 10.2 0.1 0.1 0.0 6.7 0.0 45.0 0.0 0.2 0.2 0.0 0.1 0.2 2.5 0.2 12.5 0.0 0.2 0.2 57.0 15.5 0.1 1.2 0.5 0.0 26.4 0.3 2.2 2.6 8.1 0.0 0.1 25.2 1.6 0.2 0.3 0.4 0.8 0.3 0.5 0.1 0.1 0.4 0.5 1.1 0.4 0.7 0.1 0.1 0.5 0.5 0.3 0.1 0.0 1.3 0.3 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.3 0.6 1.7 2.9 1.7 0.6 0.9 1.6 1.0 1.7 0.6 1.1 5.4 0.3 12.8 25.6 0.3 1.4 5.9 2.6 7.7 5.2 2.2 7.0 4.3 0.4 12.8 14.9 0.0 2.1 0.2 0.2 132.1 0.0 1.4 0.2 0.4 0.5 3.2 5.4 0.0 0.1 1.6 0.2 1.4 59.1 1.3 9.5 0.2 0.4 1.7 0.6 0.0 0.1 42.5 2.0 2.2 2.0 0.0 0.3 2.6 0.0 0.0 1.0 1.6 1.0 0.0 0.8 17.6 97.6 0.0 0.1 1.5 80.2 0.2 8.9 3.7 0.0 2.3 1.1 0.2 0.3 48.0 15.5 0.1 2.0 0.2 32.1 15.9 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 124.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 223.1;Astrocytes: 165.2;Oligodendrocytes: 200.2;Rod photoreceptor cells: 179.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 117.6;RT4: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 14.0 6.7 9.9 3.0 16.6 0.3 11.7 8.1 10.8 18.8 22.4 5.2 0.8 13.1 25.5 22.2 13.0 7.7 6.1 14.2 10.6 26.6 1.4 22.9 5.2 16.7 13.1 28.7 4.9 17.5 16.8 3.3 10.5 11.0 2.4 124.3 6.6 10.6 1.0 55.9 2.6 7.9 8.2 4.0 4.1 15.8 13.8 7.6 20.8 5.0 11.5 20.7 22.7 20.4 13.8 6.8 117.6 11.5 48.2 41.9 0.0 25.0 51.0 9.4 11.7 0.1 6.8 0.0 5.3 28.0 3.3 44.4 20.6 37.9 18.0 0.3 15.1 11.4 14.6 0.0 5.9 20.5 0.1 27.2 11.8 6.8 22.4 19.7 0.0 0.0 0.0 19.2 0.0 6.2 1.8 7.4 26.5 0.0 5.1 4.1 0.0 0.0 35.6 57.2 6.8 9.8 7.4 16.4 13.3 18.8 9.6 0.7 0.0 9.1 6.9 0.2 3.3 19.8 0.0 0.0 9.5 0.0 4.0 0.0 0.1 0.0 0.1 1.3 0.9 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 9.9 16.6 8.1 10.8 14.2 10.6 16.7 13.1 10.5 8.2 13.8 20.4 5.3 48.1 223.1 165.2 0.6 109.4 25.6 26.3 79.1 11.6 11.2 8.9 1.8 11.5 52.0 47.8 91.8 0.2 0.3 0.1 3.9 5.0 23.2 16.9 49.4 3.7 4.8 0.8 67.0 3.7 0.1 28.8 4.1 7.7 5.1 7.5 3.6 0.1 0.3 1.7 39.3 1.1 8.2 1.4 10.6 20.8 45.7 4.5 19.6 51.5 0.5 20.3 0.0 75.4 200.2 6.2 2.7 32.7 3.0 16.0 0.1 10.9 27.3 179.0 13.1 10.1 20.8 25.4 20.5 97.8 99.4 0.3 6.6 14.0 0.7 52.5 PTPN3 PTPH1 ENSG00000070159 "Protein tyrosine phosphatase non-receptor type 3" P26045 9 109375466-109498313 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 63.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 48.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 26.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 29.4;RPTEC TERT1: 34.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038343, HPA046728" Approved NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "HPA038343: AB_10671741, HPA046728: AB_2679776" "prognostic unfavorable (6.71e-4)" "unprognostic (3.48e-1)" "unprognostic (3.64e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.27e-1)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (3.71e-2)" "unprognostic (5.38e-2)" "unprognostic (6.37e-2)" "unprognostic (3.57e-2)" "prognostic favorable (1.22e-15)" "unprognostic (1.64e-2)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (8.21e-2)" 4.0 2.2 7.1 1.7 1.0 0.1 7.5 0.0 2.6 6.6 8.5 9.5 12.4 2.2 17.7 13.2 10.1 2.7 21.1 3.2 5.2 23.0 29.5 5.7 1.1 0.3 14.7 0.6 14.8 10.7 2.9 7.3 1.6 5.9 10.1 2.5 8.5 5.1 63.5 30.1 12.9 1.4 0.4 0.3 9.7 3.2 26.7 3.6 10.1 46.9 4.4 4.2 7.2 0.4 11.1 13.5 0.5 3.5 0.0 0.0 21.1 2.3 0.0 2.9 3.2 7.2 17.7 0.0 2.4 0.1 7.3 25.8 3.7 15.2 2.9 6.2 8.2 0.0 6.2 7.5 0.1 0.0 0.1 0.2 16.0 3.6 7.7 1.2 0.0 4.5 0.0 0.1 0.2 14.0 19.3 3.3 1.6 29.4 10.0 0.1 4.4 0.3 34.0 21.1 8.6 1.8 5.9 21.8 0.0 7.1 12.5 1.8 0.1 1.0 8.2 1.4 0.0 10.4 18.2 0.0 11.2 0.0 7.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 7.1 1.0 0.0 2.6 3.2 5.2 0.3 14.7 1.6 0.4 26.7 0.4 0.4 16.0 28.4 0.7 0.5 11.9 25.9 19.3 4.0 13.4 7.8 8.6 48.6 24.3 24.7 31.3 0.0 23.6 0.1 30.0 17.6 14.5 21.5 27.6 3.1 3.3 13.1 0.0 16.1 19.2 23.7 1.8 15.8 38.4 1.3 0.9 4.6 36.3 2.6 0.0 5.2 18.7 8.2 0.0 1.8 18.5 1.2 0.8 3.6 1.0 0.7 0.3 1.0 0.5 0.6 29.1 24.0 1.9 0.2 26.1 27.9 19.2 28.4 2.2 6.6 3.2 6.0 1.6 10.4 7.0 20.6 10.8 0.8 0.4 18.4 29.0 PTPN6 "HCP, HCPH, PTP-1C, SHP-1, SHP1" ENSG00000111679 "Protein tyrosine phosphatase non-receptor type 6" P29350 12 6946468-6961316 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 131.8;lymphoid tissue: 153.5" "Cell type enhanced" "Detected in many" "B-cells: 214.6;granulocytes: 137.3;Hofbauer cells: 191.6;Kupffer cells: 146.5;Langerhans cells: 118.2;Macrophages: 152.1;NK-cells: 154.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 170.9;HL-60: 154.3;HMC-1: 648.7;THP-1: 259.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001466, CAB004572, CAB072845" Enhanced Supported Nucleoplasm,Nucleoli NA NA 6000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Nucleoli "CAB004572: AB_628251, CAB072845: , HPA001466: AB_1855930" "unprognostic (4.28e-3)" "prognostic favorable (1.87e-4)" "prognostic unfavorable (5.42e-4)" "prognostic favorable (6.65e-4)" "unprognostic (6.54e-2)" "unprognostic (7.92e-2)" "unprognostic (2.36e-1)" "unprognostic (1.44e-2)" "unprognostic (6.93e-3)" "unprognostic (3.57e-1)" "unprognostic (1.41e-2)" "unprognostic (2.61e-1)" "unprognostic (1.60e-3)" "unprognostic (1.98e-3)" "unprognostic (2.60e-2)" "unprognostic (5.91e-2)" "prognostic favorable (2.64e-8)" 14.4 15.6 3.7 102.5 3.9 131.8 11.0 4.3 4.2 11.1 6.0 21.9 30.4 6.2 10.2 12.8 13.9 20.3 4.9 3.6 5.2 12.2 19.3 49.7 153.5 7.0 4.6 2.9 11.9 13.7 10.0 19.8 6.3 11.7 21.3 0.7 17.0 9.0 2.0 18.8 42.0 12.3 5.9 128.0 28.0 3.1 6.3 71.3 12.6 4.5 127.3 27.0 7.5 10.6 16.4 30.8 0.2 0.1 0.1 0.0 28.5 0.0 0.0 0.0 0.0 16.5 36.0 11.9 8.4 0.0 0.0 18.3 0.3 21.6 0.0 7.3 6.5 170.9 3.4 13.9 0.0 154.3 648.7 0.1 15.4 0.0 6.5 0.0 0.0 60.0 0.3 1.3 0.0 34.5 55.4 92.2 8.3 38.0 5.1 50.4 0.2 86.5 16.7 30.2 2.7 0.0 5.2 24.9 0.2 20.9 7.7 259.8 0.4 0.0 0.2 0.1 0.2 0.4 0.2 5.5 0.4 66.3 0.5 676.7 368.3 1112.5 263.4 728.6 169.3 595.0 125.3 195.9 377.0 650.0 142.7 182.6 674.8 238.6 1117.7 98.7 146.8 789.3 3.7 3.9 4.3 4.2 3.6 5.2 7.0 4.6 6.3 5.9 6.3 10.6 10.5 6.4 13.8 0.7 214.6 9.1 8.2 18.8 29.6 0.0 8.6 10.0 2.1 11.5 15.3 5.5 0.0 25.6 77.7 16.0 15.6 15.8 50.4 12.1 1.5 7.5 24.7 22.9 0.9 15.4 18.3 3.0 25.0 11.8 137.3 10.9 8.9 11.6 191.6 0.0 0.9 13.2 18.3 146.5 118.2 10.5 0.9 152.1 14.2 3.7 99.7 0.5 154.5 2.0 0.1 12.6 16.9 0.0 53.5 3.9 22.8 14.3 17.2 0.5 6.6 1.6 4.0 0.3 1.3 14.6 8.7 18.5 86.2 24.5 15.6 7.8 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 208.6;lymphoid tissue: 329.9" "Cell type enhanced" "Detected in many" "B-cells: 525.2;dendritic cells: 1026.4;Macrophages: 534.1;monocytes: 554.9;NK-cells: 769.3;Plasma cells: 474.2;T-cells: 1049.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 209.9;HEL: 118.0;HL-60: 108.1;JURKAT: 266.4;MOLT-4: 161.1;THP-1: 87.0;U-266/70: 93.7;U-266/84: 91.2;U-698: 123.4;U-937: 94.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 24000000 "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" 32.8 11.6 3.8 248.5 3.3 208.6 13.9 4.4 4.3 14.9 6.9 26.4 27.4 11.3 5.6 15.1 8.4 45.7 7.3 3.5 5.6 7.0 29.6 68.6 329.9 12.9 8.6 5.7 5.6 4.0 2.9 23.5 11.5 11.6 30.5 2.0 13.8 6.6 4.6 5.7 42.9 25.3 7.9 202.5 37.9 5.5 6.9 306.9 7.0 7.6 251.2 62.1 5.2 14.7 0.4 0.0 0.2 0.2 0.0 0.0 0.8 0.3 0.3 0.1 0.0 0.0 0.1 209.9 0.3 0.7 0.2 0.3 0.0 0.2 0.4 0.6 0.0 118.0 0.2 0.1 0.0 108.1 0.7 0.0 0.0 0.3 0.0 0.4 0.5 266.4 2.4 3.3 0.3 0.1 161.1 65.0 0.5 0.2 0.2 4.6 0.4 0.3 0.1 0.1 1.2 1.8 0.1 0.4 0.5 0.2 0.3 87.0 1.3 0.0 0.8 0.8 0.4 93.7 91.2 123.4 0.1 94.5 0.4 226.1 480.0 521.4 634.4 885.8 541.8 249.0 437.0 618.1 385.8 245.8 489.8 494.1 844.3 506.9 1015.8 57.4 508.6 1340.6 3.8 3.3 4.4 4.3 3.5 5.6 12.9 8.6 11.5 7.9 6.9 14.7 12.6 44.8 62.3 0.7 525.2 15.8 0.9 0.0 4.0 0.3 6.0 9.3 4.6 5.7 14.2 1.8 0.0 0.6 1026.4 1.0 0.0 0.7 2.4 2.3 2.3 15.1 1.2 58.8 0.7 0.0 0.9 17.2 46.9 2.7 246.5 0.1 14.6 6.9 96.0 0.0 1.7 0.4 0.0 334.9 214.5 3.5 1.2 534.1 21.4 201.4 554.9 0.1 769.3 2.5 0.7 0.1 0.8 0.0 474.2 1.1 0.1 2.5 11.7 0.2 6.6 7.4 6.7 0.3 0.6 1.8 15.2 0.8 1049.1 5.4 0.9 0.8 PTPRQ DFNB84 ENSG00000139304 "Protein tyrosine phosphatase receptor type Q" 12 80402178-80680273 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 7.1;urinary bladder: 4.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Club cells: 4.4;Early spermatids: 10.9;Excitatory neurons: 11.2;Late spermatids: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.9;BJ: 3.9;HBF TERT88: 2.6;RH-30: 2.9;RT4: 3.4;SiHa: 1.9;U-2197: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA053245 Uncertain Approved Cytosol No NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053245: AB_2682087" "unprognostic (9.10e-2)" "unprognostic (1.63e-1)" "unprognostic (1.15e-1)" "unprognostic (3.30e-2)" "unprognostic (1.37e-1)" "unprognostic (1.93e-2)" "unprognostic (1.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-2)" "unprognostic (1.78e-1)" "unprognostic (4.47e-11)" "unprognostic (8.51e-3)" "unprognostic (1.47e-1)" "unprognostic (1.73e-2)" "unprognostic (2.66e-2)" 3.2 0.0 0.3 0.0 2.0 0.0 0.4 0.0 0.7 0.5 0.0 0.1 0.0 0.0 1.9 0.1 1.6 0.2 1.1 0.2 0.4 7.1 0.0 2.3 0.9 1.0 0.7 0.3 0.3 0.1 0.1 0.1 0.6 0.6 0.0 0.8 0.1 0.1 0.2 0.1 0.0 0.0 0.8 0.0 0.1 2.7 0.3 0.2 2.9 0.0 0.3 4.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 4.9 0.0 3.9 0.8 1.2 0.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.5 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 3.4 0.0 0.0 1.9 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.7 0.2 0.4 1.0 0.7 0.6 0.8 0.3 0.0 0.0 16.0 1.1 2.0 0.0 0.0 1.9 0.3 0.0 0.1 0.0 0.0 3.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.0 0.0 0.9 0.0 2.5 1.3 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4;skin 1: 31.9" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 2714.3" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 425.5;NTERA-2: 126.3;WM-115: 193.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" NA NA 3400000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavorable (9.36e-4)" 1.6 1.6 66.0 1.2 64.2 0.0 4.0 57.2 88.4 1.8 21.5 4.4 0.6 0.1 0.8 7.9 0.3 0.7 1.3 64.0 64.1 0.1 0.1 1.2 0.0 60.9 62.9 0.7 2.7 0.0 2.3 0.2 62.4 1.0 1.1 19.0 3.4 0.7 0.1 31.9 1.0 1.3 63.7 1.0 13.8 0.3 58.6 0.2 0.1 0.3 2.6 0.9 2.3 72.4 0.1 0.0 425.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 27.7 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 126.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 5.4 15.2 0.1 0.0 0.0 0.1 0.0 0.0 0.7 10.9 5.6 0.0 0.6 0.0 193.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 66.0 64.2 57.2 88.4 64.0 64.1 60.9 62.9 62.4 63.7 58.6 72.4 0.1 0.0 1.5 625.2 0.2 25.2 8.6 82.2 44.9 18.3 5.6 12.2 1.3 0.0 39.7 0.0 4.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.0 37.7 0.7 0.1 1.3 9.2 0.0 0.0 10.1 0.0 0.0 0.1 65.6 72.0 0.0 0.0 0.0 1.6 0.7 0.3 0.1 19.6 22.5 0.0 90.4 0.0 2714.3 3.6 0.9 0.3 0.0 1.2 1.8 0.0 0.1 16.9 6.6 0.0 1.2 1.7 0.1 1.6 14.8 21.5 0.3 0.2 0.5 0.0 7.8 PTTG1 "EAP1, HPTTG, PTTG, securin, TUTR1" ENSG00000164611 "PTTG1 regulator of sister chromatid separation, securin" O95997 5 160421855-160428739 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 160.1;lymphoid tissue: 144.9;testis: 175.6" "Cell type enhanced" "Detected in many" "Early spermatids: 770.5;Erythroid cells: 415.9;Langerhans cells: 412.3;Spermatocytes: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 218.0" "Lineage enriched" "Detected in all" 7 "T-cells: 218.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008373, HPA008890, HPA045034" Enhanced Supported Nucleoli,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoli "CAB008373: AB_592493, HPA008890: AB_1079717, HPA045034: AB_2679192" "unprognostic (6.48e-2)" "unprognostic (1.03e-2)" "unprognostic (1.40e-3)" "unprognostic (4.46e-3)" "unprognostic (5.81e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.62e-6)" "unprognostic (7.50e-3)" "unprognostic (5.24e-2)" "unprognostic (3.47e-2)" "unprognostic (2.13e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.23e-2)" "unprognostic (3.35e-2)" 3.7 3.5 4.2 25.2 5.3 160.1 10.9 4.1 11.5 9.6 4.0 33.9 24.6 4.8 9.6 59.7 5.0 6.1 3.5 8.1 6.6 3.0 5.3 8.7 81.5 3.9 4.8 1.8 1.5 2.3 4.3 21.2 4.2 3.1 44.1 2.4 10.3 2.7 2.5 36.0 24.1 19.2 4.0 18.6 11.8 175.6 5.3 127.0 79.3 1.3 144.9 12.5 19.9 4.7 345.4 178.2 385.8 279.5 64.4 63.3 120.8 177.5 406.1 463.4 503.5 341.1 294.9 373.3 154.7 204.2 527.5 176.1 243.5 496.1 661.2 428.3 220.3 196.7 241.8 208.6 13.0 181.5 165.6 29.6 81.5 315.4 189.5 139.9 333.4 243.3 160.7 282.3 485.4 162.3 220.7 446.1 197.5 279.3 251.4 199.4 452.4 320.7 239.6 82.6 241.0 151.3 258.6 156.3 535.6 309.3 319.9 195.7 144.8 208.3 275.9 164.9 531.3 239.2 235.6 432.3 225.9 310.4 379.6 9.7 3.2 10.3 25.5 8.7 9.6 30.9 52.3 60.6 23.9 23.5 12.7 31.4 3.0 14.6 5.8 22.6 218.0 19.8 4.2 5.3 4.1 11.5 8.1 6.6 3.9 4.8 4.2 4.0 5.3 4.7 11.8 6.4 21.5 0.0 40.0 247.9 64.5 163.6 142.3 3.4 15.8 40.5 4.0 4.3 31.1 5.5 0.0 125.4 38.3 17.7 3.9 5.8 770.5 22.7 9.3 20.6 6.0 415.9 1.3 5.3 196.2 35.6 28.1 16.7 37.5 66.2 18.5 7.1 87.5 0.0 1.6 39.2 126.1 36.3 412.3 105.1 11.1 39.1 87.2 0.0 24.7 3.5 6.2 0.0 0.6 3.0 10.7 7.9 91.4 54.1 9.0 2.0 17.1 1.0 6.6 18.6 43.2 708.0 57.3 232.0 156.1 31.9 73.7 16.8 70.3 50.3 PTX3 "TNFAIP5, TSG-14" ENSG00000163661 "Pentraxin 3" P26022 3 157436850-157443633 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 231.5;urinary bladder: 191.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 16.2;Fibroblasts: 44.7;Glandular and luminal cells: 24.0;Langerhans cells: 23.6;Macrophages: 27.0;Melanocytes: 14.2" "Cancer enhanced" "Detected in many" "glioma: 22.5" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.9;thalamus: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1219.3;ASC TERT1: 1751.7;BJ hTERT+: 1201.8;HHSteC: 2261.1;HSkMC: 2364.2;hTEC/SVTERT24-B: 1276.5;TIME: 1761.1;U-2197: 1605.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069320 Approved Approved "Plasma membrane" "Secreted to blood" NA NA 1090000 970000 "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA069320: AB_2686118" "unprognostic (1.93e-2)" "unprognostic (4.96e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (8.35e-9)" "unprognostic (5.79e-3)" "prognostic unfavorable (6.36e-4)" "unprognostic (6.03e-3)" "prognostic unfavorable (8.75e-6)" "unprognostic (2.45e-1)" "unprognostic (6.69e-2)" "unprognostic (7.60e-2)" "unprognostic (2.63e-1)" "unprognostic (2.76e-9)" "unprognostic (6.03e-3)" "unprognostic (5.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.92e-3)" 231.5 11.1 0.4 38.8 0.4 89.0 57.9 0.6 1.9 2.8 1.1 13.0 0.8 2.5 0.5 2.9 21.4 7.7 46.8 0.6 0.5 6.8 2.6 83.2 0.9 0.7 0.6 1.4 41.6 1.1 4.4 11.4 0.6 6.9 2.3 0.4 5.4 0.5 5.2 25.4 9.7 5.7 0.3 23.6 24.8 0.7 4.0 1.6 5.8 0.5 0.3 191.7 3.1 0.4 1.2 0.0 752.4 0.2 1219.3 1751.7 0.3 132.3 1201.8 56.2 60.9 0.7 7.9 0.2 460.6 157.4 87.6 0.0 0.3 1.1 110.5 0.8 0.3 2.0 0.1 0.0 2261.1 2.5 0.0 2364.2 0.8 1276.5 429.8 110.2 266.4 0.1 0.3 0.0 380.1 0.0 0.3 2.9 11.2 0.0 4.6 0.2 0.0 0.2 5.3 53.1 6.0 0.8 7.6 1.0 0.9 0.1 0.6 2.4 1761.1 252.2 12.2 1605.1 23.0 0.2 0.5 0.9 52.8 6.4 74.2 0.0 0.3 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 1.9 0.6 0.5 0.7 0.6 0.6 0.3 4.0 0.4 2.3 0.0 1.7 0.0 0.1 1.7 1.7 0.3 0.0 1.8 3.6 0.6 0.6 0.0 1.3 0.0 0.0 0.1 0.1 0.0 0.0 7.2 2.4 16.2 10.3 5.1 0.0 0.0 0.5 0.0 0.1 44.7 0.0 24.0 0.0 0.7 3.3 0.0 2.6 0.0 1.0 0.0 0.0 10.0 23.6 1.2 0.3 27.0 14.2 0.0 2.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.8 0.0 4.0 7.2 0.0 0.4 0.4 1.0 0.3 0.4 0.0 0.0 0.4 PUF60 "FIR, RoBPI, SIAHBP1" ENSG00000179950 "Poly(U) binding splicing factor 60" Q9UHX1 8 143816344-143829352 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 332.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045733, HPA052096, HPA059714" Enhanced Enhanced Nucleoplasm NA NA 70000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA045733: AB_10960503, HPA052096: AB_2681722, HPA059714: AB_2684110" "unprognostic (3.49e-2)" "unprognostic (8.78e-2)" "unprognostic (2.66e-1)" "unprognostic (4.05e-2)" "unprognostic (1.81e-2)" "unprognostic (3.47e-2)" "unprognostic (1.51e-2)" "unprognostic (4.34e-3)" "unprognostic (2.64e-2)" "unprognostic (1.07e-2)" "unprognostic (1.75e-1)" "unprognostic (5.45e-2)" "unprognostic (2.36e-2)" "unprognostic (2.64e-2)" "unprognostic (7.00e-2)" "unprognostic (2.28e-2)" "unprognostic (3.42e-2)" 71.6 73.5 7.9 11.0 7.6 39.6 75.5 8.1 22.9 71.4 5.3 84.8 22.3 84.9 5.9 84.9 76.3 7.3 88.5 7.8 15.4 82.8 124.3 64.0 17.7 12.2 11.6 57.2 62.9 11.7 71.0 19.2 14.1 67.2 5.8 1.3 63.3 17.8 125.5 108.7 69.5 10.5 7.3 72.3 73.2 70.8 14.5 15.9 59.8 9.0 9.7 74.5 68.6 12.4 95.7 211.5 36.7 31.3 16.6 15.6 62.7 74.4 27.4 70.3 75.1 95.4 103.9 89.4 71.2 58.9 52.8 83.0 86.5 91.4 3.6 91.4 147.7 110.2 117.0 106.3 60.4 38.5 70.0 45.4 61.8 89.8 26.9 21.1 69.0 92.1 88.7 37.4 20.5 332.5 156.1 26.4 77.8 63.3 191.6 84.2 42.9 91.8 19.5 91.8 71.5 80.3 101.6 40.4 77.7 9.1 116.7 21.4 79.0 72.9 176.2 85.7 98.6 66.7 103.9 109.7 70.7 73.3 71.9 90.8 112.6 99.8 129.0 133.7 139.3 116.8 103.1 128.6 127.1 135.9 98.6 113.1 58.8 132.6 137.6 76.8 139.0 193.9 7.9 7.6 8.1 22.9 7.8 15.4 12.2 11.6 14.1 7.3 14.5 12.4 70.2 38.5 46.4 21.5 64.7 107.7 102.1 197.4 65.4 62.8 51.3 67.9 63.7 51.5 103.0 29.5 29.2 146.6 56.4 98.0 92.0 110.7 20.5 65.6 55.3 67.3 66.9 65.0 8.2 89.8 134.3 68.4 74.9 60.3 55.8 75.0 41.7 76.8 101.1 43.7 8.3 75.9 118.0 44.0 62.3 47.8 64.0 52.3 90.7 6.5 105.2 182.6 81.4 9.5 23.7 98.2 91.4 59.0 52.7 83.0 91.9 118.1 85.4 64.8 65.7 57.1 122.9 104.2 128.5 63.1 107.1 173.3 74.2 99.3 97.7 81.2 PXMP2 "MPV17L3, PMP22" ENSG00000176894 "Peroxisomal membrane protein 2" Q9NR77 12 132687587-132704985 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 312.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.3;Hepatocytes: 577.4;Proximal enterocytes: 333.3;Proximal tubular cells: 303.7" "Cancer enhanced" "Detected in all" "liver cancer: 43.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 85: Liver - Metabolism" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.12e-2)" "unprognostic (7.96e-2)" "unprognostic (4.70e-3)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (7.39e-3)" "unprognostic (2.83e-1)" "unprognostic (2.44e-2)" "unprognostic (3.02e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.75e-4)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.71e-3)" "unprognostic (3.04e-1)" 24.8 14.7 23.7 7.5 24.3 23.4 18.7 24.5 29.8 14.3 37.7 49.5 52.1 14.9 22.3 16.2 18.7 15.4 62.9 28.5 24.1 58.2 312.0 12.9 11.5 24.1 24.2 23.0 42.5 14.5 9.3 8.1 22.9 19.8 39.2 7.5 18.6 9.7 42.3 16.8 55.1 9.5 23.0 13.1 98.2 9.1 24.9 25.9 14.7 30.5 10.7 15.9 12.8 23.5 60.5 24.8 36.6 34.1 21.5 16.6 21.4 21.0 19.4 44.7 39.6 30.3 22.4 37.2 24.9 30.0 15.7 42.0 49.1 26.6 24.3 21.3 77.8 33.2 43.9 33.8 41.7 24.8 14.4 21.7 21.8 18.6 14.7 31.2 12.1 56.2 58.2 28.4 23.8 54.2 78.9 39.2 35.7 70.0 33.9 80.1 39.2 30.6 32.9 25.2 69.0 22.5 45.6 23.6 29.6 28.1 63.2 56.0 14.3 21.9 51.1 19.1 35.6 25.7 26.7 60.6 24.6 34.9 17.7 0.0 1.2 2.9 2.3 0.6 2.1 2.5 1.8 2.4 2.1 2.7 1.8 1.5 0.7 1.5 0.6 6.3 3.1 1.2 23.7 24.3 24.5 29.8 28.5 24.1 24.1 24.2 22.9 23.0 24.9 23.5 10.9 3.2 7.2 8.1 8.2 8.4 20.0 10.6 15.4 6.1 50.3 51.1 35.8 138.7 6.0 25.8 4.2 60.1 7.3 187.3 166.3 16.5 18.7 11.8 16.9 14.1 18.7 55.9 5.9 10.3 36.6 17.0 65.7 17.4 4.5 32.4 46.8 577.4 34.9 0.0 7.1 85.1 2.0 19.2 9.4 38.8 31.1 8.1 12.4 5.6 2.7 45.5 13.4 4.5 1.0 10.2 143.4 35.0 20.9 28.1 333.3 303.7 2.1 7.3 19.7 7.5 14.8 44.9 30.2 31.2 10.7 28.5 8.1 12.4 158.6 23.2 PXMP4 PMP24 ENSG00000101417 "Peroxisomal membrane protein 4" Q9Y6I8 20 33702758-33720319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 73.6;Late spermatids: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 42.3;SK-BR-3: 75.8;T-47d: 64.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050077 Approved Approved "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Peroxisomes "Nucleoli fibrillar center" "HPA050077: AB_2681006" "unprognostic (3.41e-2)" "unprognostic (1.11e-1)" "unprognostic (2.59e-1)" "unprognostic (1.75e-1)" "unprognostic (5.08e-2)" "unprognostic (1.30e-2)" "unprognostic (1.17e-1)" "prognostic favorable (3.88e-4)" "unprognostic (3.53e-1)" "unprognostic (4.47e-2)" "unprognostic (4.32e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.03e-10)" "unprognostic (3.84e-2)" "unprognostic (2.20e-1)" "unprognostic (6.08e-2)" "unprognostic (2.20e-1)" 4.1 11.2 5.1 3.0 5.2 3.2 11.9 3.8 5.6 5.6 4.3 6.2 8.2 4.1 5.1 6.3 6.0 3.3 6.4 5.0 4.0 4.9 8.9 13.9 3.6 4.6 4.5 6.8 6.8 14.7 3.5 3.2 4.1 8.7 5.7 4.4 15.2 6.4 8.0 11.1 7.4 5.1 4.2 4.6 6.8 2.5 5.3 3.5 11.5 6.9 3.9 5.4 5.8 6.5 2.8 12.1 3.3 11.9 5.7 8.3 8.5 8.7 4.7 6.6 2.9 42.3 13.2 0.1 16.2 7.3 16.1 12.5 9.0 10.1 4.7 3.7 3.4 14.0 9.7 0.1 5.3 0.7 10.3 6.4 10.8 9.0 3.0 3.3 4.3 4.4 7.9 8.6 4.7 26.4 12.9 9.8 0.3 21.7 0.0 6.8 16.3 1.7 4.2 9.0 10.7 5.4 24.2 75.8 7.9 1.9 64.0 4.7 8.2 4.7 5.4 11.9 8.2 5.5 13.2 0.2 9.0 4.6 8.1 2.2 11.1 17.5 10.8 22.2 11.3 7.6 10.9 10.9 8.8 9.9 8.3 11.2 2.9 9.1 34.2 5.3 8.5 8.6 5.1 5.2 3.8 5.6 5.0 4.0 4.6 4.5 4.1 4.2 5.3 6.5 5.2 19.2 73.6 7.2 5.5 1.7 4.3 9.4 4.0 11.1 16.8 12.3 12.6 7.2 17.8 18.4 14.6 12.9 3.5 14.2 9.8 8.2 28.7 6.3 6.1 7.6 4.2 9.9 6.4 9.9 24.3 8.5 6.6 5.7 3.8 6.7 8.9 36.0 15.1 5.0 5.7 10.8 6.1 7.5 1.6 44.0 10.5 6.2 3.6 6.5 7.5 13.6 9.2 9.0 10.8 8.5 10.3 11.3 7.0 4.5 23.0 11.2 7.8 11.4 6.6 8.8 7.8 4.6 9.8 9.5 2.4 4.4 5.8 16.9 13.0 4.0 PYCARD "ASC, CARD5, TMS-1" ENSG00000103490 "PYD and CARD domain containing" Q9ULZ3 16 31201486-31203450 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 84.7;skin 1: 90.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 425.8;Kupffer cells: 555.8;Macrophages: 344.2;Paneth cells: 360.0;Proximal enterocytes: 504.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 585.7;classical monocyte: 1098.3;eosinophil: 948.1;intermediate monocyte: 1138.3;myeloid DC: 829.2;neutrophil: 1638.4;non-classical monocyte: 1152.8;plasmacytoid DC: 769.2" "Group enriched" "Detected in all" 6 "dendritic cells: 829.2;granulocytes: 1638.4;monocytes: 1152.8" "Cell line enhanced" "Detected in many" "MCF7: 148.9;NB-4: 237.0;THP-1: 186.9;U-937: 112.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006853, CAB015948, HPA049074, HPA054496" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA 640000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Nucleoli, Cytosol" "CAB006853: , CAB015948: , HPA049074: AB_2680621, HPA054496: AB_2682506" "unprognostic (1.00e-3)" "unprognostic (2.62e-2)" "unprognostic (2.40e-1)" "unprognostic (4.67e-3)" "unprognostic (3.34e-1)" "unprognostic (1.87e-1)" "unprognostic (5.29e-2)" "unprognostic (2.88e-2)" "unprognostic (3.12e-1)" "unprognostic (2.33e-1)" "unprognostic (6.52e-3)" "unprognostic (3.88e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (4.45e-3)" "unprognostic (2.51e-1)" "unprognostic (3.61e-2)" "unprognostic (6.97e-2)" 25.6 11.4 4.1 32.9 4.0 43.4 20.4 4.6 8.6 22.1 5.0 48.1 63.9 10.7 0.0 56.1 17.4 4.9 9.7 3.7 5.2 10.9 10.4 32.8 19.1 7.8 5.1 14.9 11.3 1.7 7.7 6.1 6.7 19.9 9.5 0.1 24.6 8.7 3.4 90.5 48.5 5.8 7.6 84.7 22.1 2.3 6.7 9.5 9.1 1.2 12.7 19.8 33.1 11.3 23.9 54.8 0.5 0.2 9.2 18.9 0.6 12.6 22.6 8.8 6.5 0.1 31.7 10.6 0.1 17.6 0.0 69.7 2.9 57.4 0.3 73.0 0.0 9.3 7.9 18.3 25.6 86.9 65.7 24.7 30.3 4.0 1.2 0.2 18.4 0.1 42.9 17.5 2.9 148.9 0.2 237.0 15.7 13.2 0.1 75.5 0.0 35.2 1.3 22.3 0.7 0.2 10.4 0.0 12.4 0.3 15.5 186.9 11.8 0.4 0.7 9.9 0.3 0.6 0.1 0.2 6.4 112.1 0.1 585.7 1098.3 948.1 178.4 1138.3 112.2 213.7 146.5 183.3 829.2 210.7 102.1 139.6 1638.4 219.2 1152.8 769.2 206.4 814.2 4.1 4.0 4.6 8.6 3.7 5.2 7.8 5.1 6.7 7.6 6.7 11.3 35.7 22.4 28.9 0.0 58.5 74.1 66.3 237.0 100.7 0.2 92.2 131.7 2.5 41.5 84.3 25.8 0.0 62.5 158.8 184.5 5.9 90.5 0.8 18.6 16.8 39.2 58.9 42.9 0.1 56.5 11.3 39.3 50.4 7.3 110.9 60.2 48.9 3.3 425.8 0.0 0.1 144.6 75.3 555.8 280.2 2.9 47.2 344.2 97.8 13.1 277.8 0.0 132.8 0.0 0.1 60.4 360.0 22.6 54.1 22.6 504.8 3.6 88.2 0.7 26.3 10.5 28.5 0.3 1.4 83.9 163.7 17.8 70.8 119.9 287.1 70.6 PYGO2 ENSG00000163348 "Pygopus family PHD finger 2" Q9BRQ0 1 154957026-154963853 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023689, HPA074813" Supported Supported "Nucleoplasm,Plasma membrane" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane" "HPA023689: AB_1855974, HPA074813: " "unprognostic (1.49e-2)" "unprognostic (1.33e-1)" "unprognostic (6.96e-3)" "unprognostic (2.58e-2)" "unprognostic (5.85e-2)" "unprognostic (4.32e-3)" "prognostic unfavorable (3.88e-6)" "unprognostic (2.45e-1)" "unprognostic (2.07e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (3.74e-1)" "unprognostic (7.40e-3)" "unprognostic (1.63e-2)" "unprognostic (2.81e-2)" "unprognostic (2.17e-1)" "prognostic favorable (1.76e-4)" 14.6 30.6 30.0 16.7 30.3 6.5 15.3 29.3 29.8 21.4 21.1 23.5 19.0 19.1 23.5 24.2 20.3 12.7 15.5 29.9 34.0 24.7 20.1 15.7 26.5 30.5 30.8 27.2 18.1 27.5 32.4 16.3 29.1 23.5 15.3 12.7 23.2 23.3 18.9 22.4 24.4 15.7 29.8 28.2 21.6 16.1 35.3 22.5 26.2 15.9 27.8 21.2 20.0 32.3 28.1 19.4 40.4 36.0 39.8 19.5 37.0 17.1 23.0 26.5 22.7 26.1 34.2 34.9 26.4 19.9 28.7 37.2 35.6 23.7 17.4 34.7 25.1 27.9 32.7 23.6 18.5 25.8 23.9 16.2 33.8 23.9 20.0 30.0 16.5 52.5 37.1 57.6 25.2 42.8 36.0 30.0 43.3 55.7 34.2 40.2 25.7 55.6 27.1 26.1 48.4 71.8 27.0 48.5 34.9 39.1 59.7 45.9 14.1 23.5 35.1 25.6 25.1 56.8 54.3 37.1 19.6 32.4 31.8 2.3 3.9 10.9 8.0 6.5 10.0 6.9 10.3 10.7 4.1 7.5 11.0 8.7 3.8 6.3 8.4 3.9 5.8 6.2 30.0 30.3 29.3 29.8 29.9 34.0 30.5 30.8 29.1 29.8 35.3 32.3 7.0 9.6 4.9 5.5 12.6 5.5 3.8 5.8 7.4 11.8 14.3 10.0 5.3 5.7 7.4 12.9 2.1 15.5 14.1 10.3 19.6 6.2 3.4 5.7 7.5 6.8 5.4 12.4 6.3 5.9 12.6 5.8 9.7 7.4 0.0 9.3 7.1 9.4 6.5 21.9 4.3 10.6 6.1 6.6 3.5 2.2 9.0 5.6 5.4 6.5 6.4 10.6 8.2 5.5 4.7 9.7 9.1 9.1 11.5 4.9 12.0 9.8 4.0 6.0 6.6 5.4 6.9 5.9 12.2 9.8 5.3 11.6 11.7 9.3 8.4 3.7 PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: AB_2269494, HPA039717: AB_2676644, HPA046200: AB_10965556" "unprognostic (3.03e-2)" "unprognostic (1.00e-1)" "unprognostic (5.65e-2)" "unprognostic (8.82e-2)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.44e-2)" "unprognostic (3.94e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-2)" "unprognostic (1.59e-2)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" 24.5 30.8 19.8 24.0 20.2 22.5 27.9 21.5 24.8 26.1 22.9 31.1 31.6 22.1 41.5 72.3 22.7 19.8 21.8 19.5 20.7 26.3 43.0 20.8 35.4 20.5 20.6 17.1 28.0 26.3 22.3 22.8 20.5 31.2 30.0 17.4 34.0 15.9 29.8 41.9 29.5 19.8 20.1 31.1 24.1 25.9 20.1 33.2 27.0 29.0 42.1 24.8 31.4 20.2 50.3 39.1 56.1 31.4 33.4 43.2 92.6 36.1 43.1 33.3 28.0 57.7 57.9 62.9 53.6 35.1 15.4 38.6 43.6 77.1 26.7 48.6 32.7 51.0 35.1 71.8 40.7 59.7 44.7 39.2 48.8 37.7 56.0 42.2 35.9 27.3 44.5 67.4 39.7 75.3 38.6 105.7 98.3 56.7 20.2 34.3 22.3 72.5 69.5 69.8 37.7 43.4 46.2 61.1 33.1 51.8 74.5 124.0 28.2 20.0 28.3 31.5 26.6 35.5 58.2 97.2 34.2 40.9 31.9 17.5 79.8 75.8 58.5 92.2 72.3 98.1 105.4 82.2 120.2 88.2 68.7 69.5 19.1 53.1 66.5 65.6 186.0 87.2 19.8 20.2 21.5 24.8 19.5 20.7 20.5 20.6 20.5 20.1 20.1 20.2 16.2 19.2 17.3 0.0 28.6 0.0 29.4 0.0 21.1 12.7 41.7 38.4 0.0 25.8 14.2 23.9 8.4 84.3 21.1 29.8 78.2 40.6 15.2 21.1 17.0 16.3 7.3 32.2 0.0 50.6 76.3 17.6 22.4 21.1 18.9 14.5 22.9 44.3 55.2 6.7 0.0 32.1 0.0 47.7 0.0 11.7 23.3 42.8 0.0 0.0 110.4 55.7 48.4 0.0 0.0 54.1 33.7 23.7 21.9 34.7 66.8 61.3 16.8 13.6 13.1 18.0 15.7 23.8 25.6 63.1 0.0 62.0 29.6 16.5 29.3 34.3 PZP CPAMD6 ENSG00000126838 "PZP alpha-2-macroglobulin like" P20742 12 9148840-9208395 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 81.6" "Group enriched" "Detected in some" 4 "Early spermatids: 26.2;Hepatocytes: 26.4;Late spermatids: 11.0;Oligodendrocyte precursor cells: 8.5;Respiratory ciliated cells: 24.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.0;liver cancer: 0.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Group enriched" "Detected in some" 9 "HeLa: 5.7;SiHa: 2.5" "HPA041403, HPA041471" Supported "Secreted to blood" NA NA 15000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA041403: AB_10804003, HPA041471: AB_10795636" "unprognostic (8.48e-3)" "unprognostic (1.12e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-4)" "unprognostic (4.79e-1)" "unprognostic (3.50e-2)" "unprognostic (2.04e-4)" "unprognostic (4.57e-2)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (9.71e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-5)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (9.81e-3)" 0.2 0.0 0.4 0.0 1.3 0.1 0.2 0.9 0.6 0.2 0.6 0.0 0.0 1.3 0.1 0.0 1.2 0.0 0.7 0.9 0.6 0.2 81.6 0.8 0.0 2.3 6.7 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 0.6 0.0 2.3 1.0 0.0 0.1 0.1 0.0 0.1 0.1 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 1.1 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.9 0.6 0.9 0.6 2.3 6.7 3.9 0.9 1.0 1.3 1.9 3.2 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.8 0.0 0.0 1.6 0.0 2.7 0.0 2.1 0.0 1.4 0.0 0.0 0.0 26.2 4.7 0.2 2.1 0.0 0.0 3.7 0.0 0.0 0.1 0.0 1.7 0.0 0.0 1.8 26.4 0.0 0.0 2.9 0.0 0.0 0.3 0.0 11.0 0.0 0.2 0.0 2.8 0.0 0.0 2.1 8.5 4.6 0.0 0.0 0.4 0.7 0.0 0.0 0.0 24.7 0.6 0.0 0.3 0.4 0.5 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 QDPR "DHPR, PKU2, SDR33C1" ENSG00000151552 "Quinoid dihydropteridine reductase" P09417 4 17460261-17512206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Oxidoreductase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 752.2;choroid plexus: 301.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 337.6;Muller glia cells: 387.2;Oligodendrocytes: 481.3;Proximal tubular cells: 527.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058951, HPA065649" Enhanced Approved Mitochondria NA NA 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA058951: AB_2683861, HPA065649: AB_2685526" "unprognostic (1.30e-2)" "unprognostic (4.29e-1)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (3.29e-3)" "unprognostic (3.80e-3)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (6.82e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.84e-6)" "unprognostic (1.58e-1)" "unprognostic (2.60e-1)" "unprognostic (9.01e-2)" "unprognostic (3.19e-1)" 66.6 74.3 515.1 10.2 720.1 15.1 26.4 696.9 571.9 15.8 301.8 21.2 25.6 16.5 40.1 15.6 17.3 17.7 43.4 457.6 578.5 110.1 197.2 23.3 11.9 663.0 752.2 18.3 28.8 49.9 32.7 11.8 688.6 28.7 17.0 40.1 36.3 19.5 108.6 16.2 23.9 17.9 524.9 14.3 23.7 12.4 602.6 13.6 22.1 61.2 13.3 14.5 15.1 663.7 33.1 62.5 30.2 35.8 66.1 32.3 41.5 43.2 22.3 47.5 41.6 52.2 46.4 12.2 28.0 30.3 50.8 18.4 40.3 58.4 33.7 35.3 7.3 34.8 33.4 128.3 37.3 46.2 2.9 40.8 35.6 31.6 40.3 25.9 24.5 33.2 37.0 29.0 50.6 19.2 65.0 77.8 44.8 36.7 45.4 27.0 21.0 52.2 48.2 17.5 47.1 64.3 31.9 6.7 156.6 35.0 15.7 19.0 37.7 23.6 41.1 26.5 38.2 43.1 67.7 85.3 52.0 43.1 41.7 0.3 38.9 3.0 31.3 61.3 29.8 18.6 33.1 32.3 48.3 18.3 37.4 32.6 1.1 29.8 48.4 115.1 20.3 34.4 515.1 720.1 696.9 571.9 457.6 578.5 663.0 752.2 688.6 524.9 602.6 663.7 20.3 28.9 31.5 10.7 14.8 20.0 21.3 32.2 18.8 36.2 37.6 28.3 74.4 50.1 19.5 38.6 8.4 69.6 22.8 13.7 109.5 41.1 1.0 11.8 19.1 17.2 174.3 30.1 23.1 23.4 34.2 27.1 27.5 17.8 25.4 42.3 20.7 337.6 80.3 82.4 21.9 31.1 34.6 38.1 23.9 4.8 22.7 32.2 152.9 12.2 23.4 387.2 16.5 15.1 481.3 16.9 11.6 38.0 23.6 23.2 41.4 527.2 6.2 31.4 26.3 27.5 25.4 3.3 58.9 29.7 16.1 18.3 18.5 90.0 35.7 17.3 QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29663279-29698699 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 119.4;liver: 183.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 404.7;Extravillous trophoblasts: 315.1;Hepatocytes: 367.4;Proximal tubular cells: 598.8;Syncytiotrophoblasts: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 4.2;intermediate monocyte: 5.3;myeloid DC: 5.8;non-classical monocyte: 9.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 5.8;monocytes: 9.0" "Cell line enhanced" "Detected in many" "EFO-21: 597.1;Hep G2: 258.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011887, HPA076010" Enhanced Approved Vesicles "Intracellular and membrane" NA NA 780000 "Cluster 7: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA011887: AB_2668555, HPA076010: " "prognostic unfavorable (5.10e-5)" "unprognostic (2.00e-1)" "unprognostic (9.48e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (9.31e-4)" "unprognostic (1.44e-2)" "unprognostic (8.75e-2)" "unprognostic (1.22e-1)" "unprognostic (8.16e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (6.81e-2)" "unprognostic (3.37e-2)" "unprognostic (1.33e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-2)" 8.4 89.4 20.6 4.3 20.2 4.8 6.7 25.8 19.8 50.6 19.4 19.2 61.6 26.1 95.2 4.0 43.6 10.2 26.8 18.5 22.2 119.4 183.5 9.2 6.8 28.6 26.6 31.0 34.5 16.2 5.8 27.3 32.4 7.0 15.2 7.5 13.4 26.1 5.1 5.1 30.3 13.7 23.6 17.2 7.1 4.1 22.8 8.2 6.5 1.2 5.2 10.5 11.5 23.3 0.6 1.4 51.8 56.4 8.8 21.6 167.8 6.0 5.2 8.6 11.0 145.9 91.9 2.3 597.1 10.8 10.0 1.0 18.5 0.6 4.5 0.8 16.7 27.1 2.2 258.0 52.5 4.1 10.4 69.8 1.4 4.8 0.2 12.8 0.2 28.2 75.1 2.9 0.4 154.6 17.6 100.3 162.1 1.9 0.2 89.3 16.3 58.5 47.9 4.2 48.6 103.5 0.0 142.1 118.8 85.1 106.5 112.8 0.6 2.5 24.9 0.9 0.5 1.8 4.9 18.8 4.4 10.4 8.1 0.0 4.2 0.3 0.8 5.3 0.9 0.1 0.6 0.7 5.8 0.0 0.1 0.4 0.8 0.4 9.0 3.1 0.9 1.9 20.6 20.2 25.8 19.8 18.5 22.2 28.6 26.6 32.4 23.6 22.8 23.3 3.1 9.6 24.8 5.2 10.1 3.6 11.7 0.5 1.8 3.3 5.0 2.0 43.2 8.6 3.0 64.4 0.0 404.7 5.8 84.5 50.9 1.2 0.0 93.8 49.5 5.5 28.3 10.5 1.3 55.2 315.1 35.8 0.5 81.0 5.1 6.7 9.7 367.4 147.5 6.7 5.6 47.3 0.0 21.2 18.3 0.5 29.2 19.8 42.7 12.2 4.4 20.8 3.1 11.1 0.5 11.5 78.5 27.1 8.7 4.2 161.0 598.8 1.5 5.0 6.6 3.3 16.2 0.5 3.0 0.2 2.0 215.6 5.7 36.5 104.7 8.3 RAB10 ENSG00000084733 "RAB10, member RAS oncogene family" P61026 2 26034084-26137454 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045611 Approved NA Yes 4300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA045611: AB_10961124" "unprognostic (7.73e-3)" "unprognostic (2.45e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (7.40e-4)" "unprognostic (8.22e-3)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (9.22e-3)" "unprognostic (6.14e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (7.37e-5)" "unprognostic (1.06e-2)" "unprognostic (8.69e-3)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-2)" 47.4 51.5 42.8 44.2 49.0 17.7 45.1 48.7 56.7 55.6 29.7 58.8 41.3 38.9 40.3 172.9 39.6 41.9 49.8 41.2 47.3 56.8 48.5 39.9 42.8 52.9 46.9 37.1 37.7 66.3 21.5 40.9 54.4 42.6 57.9 29.0 51.7 41.6 213.9 71.0 46.3 48.1 51.5 44.4 58.8 24.0 46.4 43.8 54.2 114.0 64.5 78.5 78.1 62.8 117.1 139.7 63.8 53.1 131.2 108.2 61.9 90.3 76.8 69.7 61.6 83.2 83.8 77.9 83.4 96.7 79.5 62.0 77.3 84.4 73.9 82.3 56.0 135.1 54.4 134.8 122.6 112.2 73.5 89.0 135.9 85.9 100.3 109.6 89.0 48.9 114.1 76.7 95.1 52.0 69.1 87.1 65.2 139.5 81.7 65.2 133.4 132.8 141.6 111.8 90.1 83.7 75.2 135.1 94.9 70.5 59.5 80.1 110.2 107.1 56.2 75.7 97.2 50.5 84.2 124.4 107.9 132.6 83.5 58.0 75.5 35.5 31.5 135.2 38.6 33.4 36.9 34.1 69.9 32.0 31.1 35.2 54.6 50.6 152.6 24.3 44.6 81.0 42.8 49.0 48.7 56.7 41.2 47.3 52.9 46.9 54.4 51.5 46.4 62.8 70.8 80.1 49.7 37.9 56.2 341.8 195.5 156.4 122.3 23.8 85.2 64.6 76.4 85.8 134.7 92.0 8.4 121.0 48.7 168.8 115.4 188.3 35.5 67.8 76.7 78.4 65.2 101.0 43.6 96.0 204.4 80.7 97.3 98.3 50.7 44.0 53.2 66.8 159.7 26.9 36.0 94.1 107.8 157.2 285.1 29.6 62.7 151.6 88.9 36.5 246.8 104.9 38.1 47.7 78.1 136.8 123.8 70.0 63.6 199.7 85.9 135.2 107.4 32.7 85.5 94.1 159.5 85.3 73.4 255.9 488.0 128.3 59.3 65.6 117.7 334.3 RAB11A YL8 ENSG00000103769 "RAB11A, member RAS oncogene family" P62491 15 65726054-65891989 "Predicted intracellular proteins" "Cell cycle, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 969.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013097, HPA051697, HPA060686" Approved Enhanced "Vesicles,Centriolar satellite" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Vesicles, Centriolar satellite" "CAB013097: AB_2533987, HPA051697: AB_2732569, HPA060686: AB_2684342" "unprognostic (4.15e-2)" "unprognostic (5.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.74e-3)" "unprognostic (6.85e-2)" "unprognostic (6.07e-2)" "unprognostic (3.17e-2)" "unprognostic (7.12e-2)" "unprognostic (8.60e-2)" "unprognostic (4.83e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (4.29e-2)" "prognostic favorable (1.46e-5)" "unprognostic (9.93e-2)" "unprognostic (1.83e-2)" "unprognostic (5.23e-3)" "unprognostic (1.21e-1)" 140.0 231.6 79.7 123.9 86.4 126.0 150.1 83.4 105.0 159.3 78.5 223.8 139.8 117.4 130.9 480.0 146.1 185.1 156.3 86.1 97.4 162.9 124.1 148.1 141.2 87.0 83.0 104.9 107.6 192.5 106.8 214.4 101.3 150.3 224.2 99.0 195.1 126.2 119.6 288.5 158.9 149.2 87.2 183.9 216.2 201.8 86.0 143.6 155.3 109.6 246.0 269.8 232.2 86.7 285.2 330.3 330.1 240.8 294.7 275.0 431.1 297.0 300.4 264.4 313.0 305.8 497.4 370.7 295.8 342.6 262.3 429.0 525.0 393.2 248.2 243.7 314.9 445.3 219.9 274.1 224.7 211.5 254.0 282.8 438.1 260.2 214.7 281.7 595.2 197.8 364.5 214.3 378.1 283.7 209.9 167.3 275.9 1057.4 185.9 176.3 250.5 346.3 716.1 734.7 237.4 251.9 214.0 335.6 286.5 387.8 445.0 243.0 453.7 208.4 296.4 203.1 267.8 112.2 289.5 288.8 193.7 353.5 228.8 183.5 154.8 235.2 56.7 133.9 58.8 78.8 85.3 68.6 137.1 64.1 78.9 63.6 232.8 71.3 154.6 87.6 109.5 340.2 79.7 86.4 83.4 105.0 86.1 97.4 87.0 83.0 101.3 87.2 86.0 86.7 155.7 57.7 57.8 15.3 90.2 192.2 180.2 375.2 134.3 42.3 107.5 69.6 89.5 105.8 245.4 187.6 33.3 326.4 76.0 313.4 346.3 360.6 413.1 119.3 72.7 260.7 206.2 91.1 31.3 337.0 340.4 96.9 149.9 194.5 74.9 75.9 235.2 88.4 239.2 57.2 27.7 227.4 244.1 114.8 214.2 80.9 97.3 148.1 186.7 42.2 217.8 137.9 65.9 25.6 21.9 391.1 277.0 86.5 72.1 187.6 205.8 271.5 240.0 36.1 46.0 45.2 161.5 407.5 95.3 225.5 284.4 969.3 96.6 97.6 209.2 360.8 RAB11FIP1 "FLJ22524, FLJ22622, Rab11-FIP1, RCP" ENSG00000156675 "RAB11 family interacting protein 1" Q6WKZ4 8 37858618-37899497 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 798.0;Endometrial ciliated cells: 622.9;Glandular and luminal cells: 969.7;Urothelial cells: 613.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 101.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 101.9" "Cell line enhanced" "Detected in many" "K-562: 73.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017037, HPA023904, HPA024010, HPA025960" Enhanced Enhanced Vesicles No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "CAB017037: , HPA023904: AB_1855990, HPA024010: AB_1855991, HPA025960: AB_1855992" "unprognostic (1.62e-2)" "unprognostic (3.47e-2)" "unprognostic (3.22e-3)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "prognostic favorable (6.61e-4)" "unprognostic (4.32e-1)" "unprognostic (4.50e-3)" "unprognostic (1.58e-1)" "unprognostic (4.72e-2)" "unprognostic (2.82e-3)" "unprognostic (2.73e-2)" "prognostic favorable (1.14e-6)" "unprognostic (4.94e-2)" "unprognostic (8.41e-2)" "unprognostic (9.99e-2)" "unprognostic (1.50e-1)" 7.5 5.7 3.8 17.7 2.7 58.5 21.8 3.8 3.8 14.5 39.3 40.7 41.3 5.9 14.8 47.1 16.9 21.7 12.0 4.4 4.3 13.7 7.2 74.0 17.2 3.4 2.7 4.6 42.5 12.0 8.6 25.8 2.1 8.7 47.0 6.1 23.8 13.5 4.6 18.9 53.5 7.1 2.3 12.0 45.5 6.4 4.0 15.4 13.0 2.7 31.1 23.6 14.9 2.2 41.8 18.1 1.9 8.0 0.4 0.1 54.1 4.2 6.6 7.5 9.6 40.6 23.2 17.0 12.7 5.1 0.4 31.6 14.5 9.4 11.3 44.2 13.5 3.3 9.0 11.9 20.9 7.3 36.3 4.8 12.2 2.8 7.9 11.1 0.1 22.2 73.1 8.2 3.8 9.9 12.4 10.7 12.0 40.9 5.3 3.9 9.7 13.2 39.4 42.2 7.4 8.5 10.6 52.3 13.0 36.8 35.2 14.0 0.6 0.2 23.1 0.6 0.7 16.5 20.7 4.5 0.3 9.8 5.7 24.0 20.5 38.1 4.4 9.4 9.9 6.0 3.2 3.1 18.3 3.8 2.0 2.2 101.9 10.9 20.2 11.0 7.7 10.7 3.8 2.7 3.8 3.8 4.4 4.3 3.4 2.7 2.1 2.3 4.0 2.2 7.6 798.0 112.9 1.0 128.5 15.9 113.5 49.5 24.5 5.4 113.6 58.5 15.8 84.4 228.0 64.4 16.7 44.9 123.6 385.5 15.6 170.2 0.9 622.9 71.4 25.3 243.7 3.8 7.9 248.9 8.1 28.7 272.7 969.7 30.4 2.8 32.2 15.3 32.1 6.7 8.6 312.3 95.6 59.1 174.7 1.8 1.8 121.1 16.0 2.8 95.2 18.6 120.5 0.0 1.0 364.6 299.1 1.5 48.2 192.7 331.9 16.5 348.8 21.0 6.6 9.0 23.3 2.4 5.2 124.2 30.5 96.0 83.8 2.8 256.6 613.9 RAB11FIP4 "FLJ00131, KIAA1821, MGC11316, RAB11-FIP4" ENSG00000131242 "RAB11 family interacting protein 4" Q86YS3 17 31391675-31538211 "Predicted intracellular proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;testis: 48.8" "Cell type enhanced" "Detected in many" "Early spermatids: 334.6;Horizontal cells: 212.0;Late spermatids: 1251.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 78.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 78.7" "Cell line enhanced" "Detected in many" "BEWO: 64.3;Daudi: 36.8;Hep G2: 40.6;HMC-1: 41.5;RT4: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063203 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA063203: AB_2684962" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "prognostic favorable (2.70e-4)" "unprognostic (6.03e-3)" "unprognostic (4.29e-2)" "unprognostic (4.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.20e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.74e-8)" "prognostic favorable (1.22e-4)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (4.13e-3)" 0.9 1.1 68.9 8.1 72.0 15.0 4.1 48.9 71.4 2.7 22.0 9.3 12.9 1.2 11.2 6.7 7.5 3.2 2.7 66.2 47.6 6.8 2.9 5.7 11.8 55.3 66.0 2.4 17.6 6.1 3.5 10.5 51.7 2.5 7.3 7.7 7.4 3.8 0.5 8.1 14.7 0.9 54.3 7.4 13.4 48.8 70.7 4.6 4.6 0.4 10.7 5.1 2.1 78.4 12.4 1.4 1.3 3.2 0.5 0.0 64.3 0.2 0.0 0.8 0.8 20.7 1.9 36.8 4.6 0.2 13.3 10.3 12.2 5.9 0.5 7.5 11.0 0.0 0.5 40.6 0.3 2.7 41.5 0.3 5.9 0.8 2.6 0.4 0.0 10.9 2.7 0.9 0.0 9.8 2.7 0.7 10.5 22.9 0.4 1.0 0.1 7.1 2.3 37.8 19.1 13.9 2.8 17.4 14.6 8.7 25.7 1.2 0.0 0.7 6.3 0.1 0.6 6.6 5.6 3.4 0.2 3.7 2.5 5.5 8.4 78.7 13.9 11.9 8.7 5.8 7.2 10.3 5.4 8.6 7.6 9.1 40.5 6.4 15.8 1.1 9.6 8.7 68.9 72.0 48.9 71.4 66.2 47.6 55.3 66.0 51.7 54.3 70.7 78.4 0.6 6.4 8.3 15.7 12.1 3.1 11.4 5.7 1.8 9.6 9.1 5.2 7.3 15.7 9.6 11.0 10.4 73.1 19.8 32.6 13.7 17.5 334.6 39.0 3.9 1.5 14.9 2.7 68.6 28.2 10.9 2.3 17.3 48.8 12.0 7.3 1.1 4.4 6.0 212.0 71.0 16.0 12.2 1.9 5.7 1251.4 5.3 6.3 10.6 1.9 11.1 53.7 26.8 13.6 72.3 24.8 20.2 4.9 7.0 11.1 25.9 12.4 18.1 7.4 0.0 3.1 2.7 8.3 9.7 4.4 3.0 50.3 15.2 0.2 21.1 15.4 RAB14 "FBP, RAB-14" ENSG00000119396 "RAB14, member RAS oncogene family" P61106 9 121178133-121223014 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026419, CAB037066" Approved Supported Vesicles NA NA 2700000 "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB037066: AB_1841128, HPA026419: AB_1855996" "unprognostic (1.30e-3)" "unprognostic (3.12e-2)" "unprognostic (9.01e-2)" "unprognostic (7.18e-2)" "unprognostic (6.53e-2)" "unprognostic (3.00e-1)" "unprognostic (1.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.52e-1)" "unprognostic (6.90e-2)" "unprognostic (3.05e-2)" "unprognostic (9.71e-3)" "prognostic favorable (1.79e-8)" "unprognostic (1.38e-1)" "unprognostic (3.17e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" 39.0 38.7 37.5 35.6 39.7 66.5 42.1 40.3 47.7 37.8 32.6 42.8 39.9 35.6 34.2 63.2 34.0 30.7 32.4 38.4 40.9 50.0 82.8 49.2 41.1 39.6 39.9 35.9 27.6 45.8 28.9 43.1 40.5 38.8 42.4 45.5 34.6 38.1 39.4 56.4 38.9 33.4 40.8 38.3 44.3 33.8 40.2 35.2 43.8 38.9 49.5 43.9 40.8 46.8 53.8 53.7 66.9 56.3 76.2 82.5 52.6 74.8 59.6 56.6 44.7 42.6 57.0 51.2 42.5 72.0 49.2 100.1 48.1 55.8 63.6 44.4 31.7 55.7 69.0 43.9 52.6 60.1 63.8 53.0 98.5 58.2 63.4 62.5 81.2 47.1 42.8 45.6 85.6 50.8 58.5 48.1 39.7 104.8 59.9 45.8 72.3 60.4 62.3 76.0 58.9 34.4 89.0 78.0 53.8 47.1 82.1 46.8 76.0 60.1 43.9 75.3 53.0 40.8 82.6 52.3 56.6 51.9 80.7 34.4 29.4 33.5 22.4 41.5 22.4 24.6 20.9 24.7 31.4 23.4 24.6 25.0 31.8 26.5 43.7 19.0 29.3 24.0 37.5 39.7 40.3 47.7 38.4 40.9 39.6 39.9 40.5 40.8 40.2 46.8 102.6 160.3 103.9 23.5 64.4 157.9 78.2 84.8 97.3 93.8 70.7 58.8 39.2 62.9 96.2 62.5 37.5 85.2 79.6 95.1 86.1 81.3 41.9 80.7 89.8 84.5 60.3 44.4 42.5 64.4 83.0 68.7 64.7 94.4 77.2 58.1 61.1 113.6 91.0 94.2 38.0 59.8 95.6 89.9 105.4 36.2 51.9 80.7 110.3 44.0 84.8 100.5 49.4 38.2 59.0 80.7 52.9 56.4 50.2 81.0 63.2 103.3 86.8 62.0 59.2 64.0 105.6 112.9 113.6 120.0 202.4 116.2 74.3 82.5 64.0 106.0 RAB17 ENSG00000124839 "RAB17, member RAS oncogene family" Q9H0T7 2 237574322-237601614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.7;liver: 107.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Distal tubular cells: 137.0;Hepatocytes: 121.7;Proximal enterocytes: 222.5;Proximal tubular cells: 170.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.4;Hep G2: 39.9;MCF7: 52.0;SK-BR-3: 48.1;SK-MEL-30: 86.7;T-47d: 34.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA035176 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035176: AB_10696368" "unprognostic (8.66e-2)" "unprognostic (1.13e-1)" "unprognostic (1.44e-3)" "unprognostic (9.14e-2)" "unprognostic (2.48e-3)" "unprognostic (1.26e-3)" "unprognostic (1.33e-1)" "unprognostic (5.36e-2)" "unprognostic (3.49e-2)" "unprognostic (2.68e-2)" "prognostic favorable (4.14e-4)" "unprognostic (5.87e-2)" "prognostic favorable (3.33e-13)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (3.44e-1)" "prognostic favorable (2.51e-4)" 0.8 1.0 0.9 1.6 0.6 0.4 15.0 0.6 1.3 6.7 25.8 16.4 76.7 2.3 19.4 2.1 11.1 14.7 1.5 2.2 0.7 49.8 107.6 23.1 0.4 0.8 0.7 0.6 38.7 36.9 3.0 13.8 0.7 7.0 15.6 4.2 34.8 15.3 1.4 0.9 73.7 1.0 0.6 0.5 33.5 0.7 0.9 1.0 33.4 0.0 0.8 3.8 0.3 0.7 9.5 0.3 0.0 17.7 0.1 0.2 42.4 0.2 0.1 0.0 0.1 28.7 26.6 0.0 5.6 0.2 0.1 0.4 0.0 12.5 0.2 0.0 0.0 0.0 0.1 39.9 0.0 0.2 0.0 0.0 7.8 0.0 0.9 0.7 0.0 0.1 0.0 0.0 1.0 52.0 0.0 0.6 0.5 28.6 0.1 1.1 0.0 3.4 13.7 25.1 10.5 0.1 0.0 48.1 86.7 9.4 34.8 0.7 0.0 0.2 0.6 0.1 0.1 0.1 1.2 0.0 0.1 2.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.6 1.3 2.2 0.7 0.8 0.7 0.7 0.6 0.9 0.7 1.2 60.9 34.3 0.3 0.5 1.8 3.4 3.3 22.8 1.7 32.2 18.3 1.0 65.8 11.9 46.0 106.3 16.0 0.1 49.6 137.0 40.0 0.0 18.2 1.6 1.8 30.3 0.0 0.8 28.0 3.8 0.7 29.0 22.1 0.0 0.4 2.5 121.7 1.9 0.0 1.5 23.9 24.4 2.2 0.6 0.7 8.7 1.3 5.4 0.0 0.6 0.2 0.0 1.0 0.1 27.9 50.1 3.8 0.1 5.3 222.5 170.2 13.7 0.6 0.0 0.3 0.7 0.0 0.2 6.6 0.6 12.3 1.3 0.7 21.9 6.5 RAB19 RAB19B ENSG00000146955 "RAB19, member RAS oncogene family" A4D1S5 7 140404058-140427974 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.9" "Cell type enhanced" "Detected in single" "Enteroendocrine cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.8;HDLM-2: 5.4;MCF7: 3.3;RT4: 4.8;SK-BR-3: 4.6;T-47d: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA051077 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" "HPA051077: AB_2681336" "unprognostic (3.40e-1)" "unprognostic (2.07e-2)" "unprognostic (2.26e-1)" "unprognostic (3.10e-2)" "unprognostic (1.54e-1)" "unprognostic (6.48e-2)" "unprognostic (1.65e-1)" "unprognostic (2.35e-2)" "unprognostic (3.17e-2)" "unprognostic (2.72e-2)" "unprognostic (7.91e-2)" "unprognostic (2.53e-1)" "prognostic favorable (2.36e-8)" "unprognostic (1.73e-3)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (6.09e-3)" 0.1 0.2 1.0 1.1 0.7 3.9 0.5 1.7 1.1 0.2 0.5 2.2 2.2 0.3 0.9 0.2 0.7 0.7 0.2 0.6 0.6 1.6 0.3 0.7 1.1 0.7 0.5 0.1 1.7 3.1 0.9 0.3 0.9 0.6 2.7 0.3 0.6 0.2 0.6 0.6 2.0 0.2 0.1 0.5 1.5 0.2 1.1 1.0 2.1 0.0 0.8 0.7 0.0 1.9 0.7 0.2 0.1 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.3 3.8 0.2 0.4 0.0 0.1 0.8 0.0 0.6 0.0 5.4 0.3 0.1 0.6 0.2 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.2 0.4 0.0 3.3 0.5 0.3 0.1 0.4 0.3 0.1 0.1 0.1 1.8 4.8 0.8 0.1 0.1 4.6 0.0 0.3 4.8 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.1 0.8 0.3 0.4 0.9 0.2 1.6 0.5 1.0 1.5 0.1 0.6 1.1 1.3 1.3 0.9 0.2 0.4 2.1 0.3 1.0 0.7 1.7 1.1 0.6 0.6 0.7 0.5 0.9 0.1 1.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.0 1.8 0.0 0.7 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 423.3;skin 1: 210.0" "Cell type enhanced" "Detected in many" "Paneth cells: 249.6;Squamous epithelial cells: 300.6;Undifferentiated cells: 244.6;Urothelial cells: 232.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "BEWO: 120.9;CAPAN-2: 119.9;MCF7: 171.5;OE19: 392.3;RT4: 153.4;SK-BR-3: 243.3;T-47d: 227.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010872, CAB033645" Enhanced Uncertain "Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions, Cytosol" "CAB033645: AB_1128883, HPA010872: AB_1079729" "unprognostic (2.43e-1)" "unprognostic (4.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (4.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (1.38e-6)" "unprognostic (2.31e-2)" "unprognostic (3.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.94e-2)" 0.6 0.1 0.1 10.2 0.1 0.1 52.0 0.3 0.3 76.2 0.0 86.2 72.9 7.3 37.5 423.3 47.5 26.4 0.1 0.0 0.0 41.6 1.7 39.2 0.4 0.1 0.1 0.4 57.1 68.9 27.5 12.4 0.1 36.3 78.1 0.0 105.3 28.4 0.9 210.0 65.6 3.7 0.2 0.2 80.9 0.3 0.1 10.1 50.6 0.0 44.0 69.9 148.2 0.3 93.3 0.0 0.0 0.0 0.0 0.0 120.9 0.0 0.0 0.0 0.0 90.4 119.9 0.0 0.1 0.0 0.0 109.5 0.0 51.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 105.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 171.5 0.0 0.4 4.8 392.3 0.0 0.1 0.0 0.3 0.0 153.4 13.3 0.0 0.0 243.3 0.3 21.1 227.9 0.4 0.0 0.2 0.2 0.0 0.2 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.0 0.2 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.3 0.3 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 1.2 28.9 41.0 0.0 1.5 55.1 102.9 113.9 74.0 0.0 121.4 137.7 0.1 94.4 98.7 86.5 0.0 102.1 2.3 197.8 166.3 170.4 0.0 58.6 6.4 2.6 85.4 0.0 0.1 150.3 30.0 2.3 96.4 66.2 5.7 0.0 0.0 0.4 7.3 0.0 0.1 208.5 89.5 0.0 5.8 0.0 0.3 2.1 21.4 0.0 3.6 0.0 0.0 0.0 0.1 197.3 249.6 0.0 0.3 114.0 195.9 35.5 66.3 0.0 0.0 0.0 6.8 0.2 1.1 300.6 154.7 80.3 2.7 0.0 244.6 232.3 RAB29 "RAB7L, RAB7L1" ENSG00000117280 "RAB29, member RAS oncogene family" O14966 1 205767986-205775482 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 73.1" "Cell type enhanced" "Detected in many" "dendritic cells: 82.3;monocytes: 76.4;NK-cells: 129.8;Proximal tubular cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020822, HPA026303" Approved Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB020822: , HPA026303: AB_1856016" "unprognostic (5.38e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.82e-5)" "unprognostic (9.50e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.60e-2)" "unprognostic (3.14e-1)" "unprognostic (5.50e-2)" "unprognostic (2.45e-1)" "unprognostic (3.05e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.53e-1)" "unprognostic (8.20e-3)" "unprognostic (1.42e-1)" 13.5 14.4 12.5 20.4 14.1 7.1 14.1 14.3 12.1 8.7 10.5 12.6 10.6 8.3 23.8 7.8 6.2 16.9 13.1 12.3 14.3 73.1 19.4 13.5 35.1 15.9 12.9 7.9 9.2 25.5 5.9 7.2 15.8 13.8 10.1 6.8 19.8 13.9 6.4 5.5 12.4 14.8 14.3 24.3 10.4 4.6 15.3 12.1 33.4 6.0 28.0 15.7 5.7 17.0 20.4 18.6 2.8 13.1 52.5 29.8 9.7 14.1 43.2 28.9 34.4 5.6 28.7 21.6 13.6 24.3 34.6 11.2 32.8 37.3 26.4 88.3 15.3 16.4 7.3 9.5 25.4 16.1 23.2 29.0 24.6 23.3 32.8 24.0 37.2 19.8 16.2 24.2 41.2 7.6 17.7 8.3 13.1 25.4 14.0 3.7 43.1 17.5 33.6 27.7 4.4 12.5 10.0 45.0 37.8 10.3 22.0 13.2 38.7 29.7 15.0 43.5 20.6 39.4 87.0 11.5 30.1 26.3 22.5 92.4 22.6 62.3 92.2 43.8 86.9 50.8 51.0 79.5 33.4 45.8 37.2 63.5 8.8 94.1 53.9 10.4 53.3 51.3 12.5 14.1 14.3 12.1 12.3 14.3 15.9 12.9 15.8 14.3 15.3 17.0 16.3 19.2 17.7 11.1 61.2 0.0 6.3 0.0 13.6 2.1 19.5 16.0 19.3 21.5 6.2 31.3 0.0 12.0 82.3 1.9 29.4 18.7 5.1 2.0 6.3 18.6 4.9 10.8 7.8 10.1 6.4 11.2 10.7 3.5 13.3 9.2 14.6 33.7 32.8 0.0 10.2 3.7 0.0 30.1 0.0 4.1 14.3 34.0 0.0 10.3 76.4 26.5 129.8 10.6 9.8 8.3 4.8 20.7 34.8 10.7 9.5 187.7 2.9 2.0 6.6 10.0 6.7 3.8 11.8 9.3 0.0 2.9 51.7 19.7 5.5 6.9 RAB38 NY-MEL-1 ENSG00000123892 "RAB38, member RAS oncogene family" P57729 11 88113251-88175443 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 48.6;skin 1: 44.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.4;Basal respiratory cells: 74.8;Cytotrophoblasts: 94.5;Melanocytes: 131.6;Suprabasal keratinocytes: 98.5;Syncytiotrophoblasts: 54.7" "Cancer enhanced" "Detected in all" "melanoma: 73.8" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "NK-cell: 18.0" "Lineage enriched" "Detected in many" 4 "NK-cells: 18.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 87.7;hTCEpi: 308.0;hTERT-HME1: 271.4;SK-MEL-30: 175.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "basal ganglia: 1.1" HPA071701 Uncertain "Nuclear bodies,Mitochondria" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear bodies, Mitochondria" "HPA071701: " "unprognostic (2.85e-1)" "unprognostic (1.30e-1)" "unprognostic (4.40e-2)" "unprognostic (2.66e-2)" "unprognostic (1.36e-2)" "unprognostic (7.95e-2)" "unprognostic (3.96e-4)" "unprognostic (2.36e-1)" "unprognostic (1.44e-1)" "unprognostic (9.34e-2)" "unprognostic (1.00e-2)" "unprognostic (8.23e-2)" "prognostic favorable (8.26e-4)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" 2.6 27.8 0.4 1.4 0.4 1.6 8.6 0.3 0.8 11.8 6.3 1.9 2.4 4.7 6.7 48.6 5.6 6.0 1.1 0.7 0.6 4.5 1.8 5.8 1.7 0.5 0.7 3.3 1.6 1.8 2.8 14.7 0.5 2.4 1.3 2.9 7.7 6.4 0.6 44.3 2.3 3.6 0.4 1.6 1.6 2.5 0.8 3.5 7.9 0.4 17.9 8.7 23.5 0.6 10.7 1.4 0.3 0.5 0.4 2.4 0.6 6.5 26.1 10.4 19.0 4.7 4.8 0.5 6.3 6.9 1.2 71.2 5.7 87.7 14.1 1.3 5.1 54.0 6.2 0.0 1.0 0.6 0.6 2.2 308.0 1.4 271.4 13.0 12.3 1.0 0.3 0.9 0.0 0.0 0.7 18.4 8.2 0.7 0.1 0.5 0.1 0.8 20.0 40.6 1.9 1.2 0.3 0.1 175.6 6.2 15.7 4.6 6.7 0.0 4.6 0.0 1.1 1.5 6.5 0.2 1.7 2.2 1.2 0.0 0.8 0.1 1.5 0.6 0.8 0.0 0.4 1.8 1.6 0.0 0.1 0.8 0.6 18.0 1.3 4.4 1.0 0.7 0.4 0.4 0.3 0.8 0.7 0.6 0.5 0.7 0.5 0.4 0.8 0.6 1.0 0.0 6.7 0.7 0.1 46.4 15.9 74.8 21.1 0.1 6.9 9.7 0.2 8.6 25.0 0.0 0.0 94.5 2.7 0.5 3.9 1.7 0.0 2.1 0.9 2.7 0.0 5.5 0.6 1.1 10.5 9.1 3.1 2.3 16.5 5.3 1.1 0.0 17.5 0.0 0.4 0.3 14.2 1.6 21.2 0.1 3.4 3.9 131.6 3.7 6.3 0.6 1.0 2.0 0.1 2.6 2.6 1.2 0.1 9.5 2.1 5.3 7.4 6.4 0.0 0.6 5.3 0.1 5.9 38.1 98.5 54.7 2.7 5.9 2.5 23.3 RAB40C "RARL, RASL8C" ENSG00000197562 "RAB40C, member RAS oncogene family" Q96S21 16 589357-629272 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 58.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 14.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076172 Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA076172: " "unprognostic (8.04e-2)" "unprognostic (3.63e-1)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (5.38e-3)" "unprognostic (1.07e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (5.78e-2)" "unprognostic (3.45e-2)" "unprognostic (2.90e-1)" "unprognostic (1.37e-3)" "unprognostic (3.89e-2)" "unprognostic (6.20e-2)" "unprognostic (7.48e-2)" "unprognostic (4.00e-3)" 10.5 8.0 7.4 4.5 10.0 5.8 11.6 7.1 17.7 13.2 0.0 20.3 13.3 13.0 5.1 20.4 12.2 4.5 12.5 10.9 2.0 13.9 12.8 13.3 4.1 3.4 2.6 12.1 38.5 5.1 21.4 6.6 3.2 17.5 4.4 1.9 14.3 5.9 18.8 58.0 13.6 4.4 1.5 7.9 19.3 13.8 4.0 10.2 10.6 6.2 2.6 18.3 16.1 8.8 7.7 16.3 9.4 13.2 5.3 6.6 12.6 10.1 4.7 8.0 6.5 14.7 13.7 8.8 10.5 6.0 7.1 17.1 5.8 8.3 1.6 9.3 9.8 4.9 11.3 10.5 9.4 9.9 8.9 5.6 17.9 6.4 6.7 5.6 6.6 10.3 11.2 8.8 3.5 22.7 9.6 18.0 10.9 13.5 9.4 15.4 6.7 14.1 4.7 10.9 12.8 10.3 11.1 24.1 9.4 4.3 17.8 19.6 8.2 8.4 11.8 11.3 6.1 8.4 8.6 11.0 5.5 13.4 8.9 1.1 2.8 14.0 0.4 1.8 1.9 1.1 1.4 1.5 1.6 0.7 1.0 0.7 4.8 0.8 0.8 0.7 0.6 1.3 7.4 10.0 7.1 17.7 10.9 2.0 3.4 2.6 3.2 1.5 4.0 8.8 7.1 9.6 15.7 20.5 4.3 17.5 9.9 11.3 18.2 11.4 9.8 7.9 6.3 8.6 10.4 11.0 8.4 26.6 7.7 33.2 7.9 6.2 4.0 12.1 7.1 5.4 10.8 5.2 44.5 12.5 15.3 4.7 23.4 12.7 7.0 11.2 7.5 16.2 9.4 16.8 18.6 16.5 24.4 6.1 4.1 6.6 5.0 4.5 7.2 10.3 7.5 8.4 7.2 10.6 14.8 10.4 21.3 6.4 2.5 10.8 38.2 9.7 11.2 3.3 0.0 5.6 5.8 17.1 13.9 24.8 31.1 56.8 4.6 7.2 18.7 8.6 RAB5B ENSG00000111540 "RAB5B, member RAS oncogene family" P61020 12 55973913-55996683 "Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010224, HPA068337" Approved Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB010224: AB_2175453, HPA068337: AB_2685974" "prognostic unfavorable (2.24e-5)" "unprognostic (1.86e-1)" "unprognostic (1.91e-1)" "unprognostic (7.66e-3)" "unprognostic (2.09e-1)" "unprognostic (8.42e-2)" "unprognostic (9.16e-3)" "unprognostic (3.09e-1)" "unprognostic (3.13e-1)" "unprognostic (8.31e-3)" "unprognostic (8.64e-2)" "unprognostic (2.26e-1)" "unprognostic (2.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.74e-1)" "unprognostic (2.85e-1)" "unprognostic (2.49e-1)" 50.9 54.4 95.4 39.4 102.3 35.0 68.2 106.2 96.8 76.8 76.5 72.2 52.4 73.8 92.4 99.8 75.7 55.8 87.2 93.1 99.5 70.1 68.8 72.9 44.5 103.5 105.6 85.4 47.9 112.1 31.4 63.4 106.0 74.6 80.6 72.9 61.7 94.6 100.6 92.4 50.4 79.9 103.6 48.1 67.0 57.1 99.9 64.0 64.6 127.6 76.0 65.6 69.6 112.9 62.3 39.1 80.2 59.4 128.5 115.9 72.1 56.1 102.3 68.3 57.5 67.5 76.7 34.7 65.5 107.6 50.3 44.8 51.4 77.8 63.3 44.1 39.5 39.3 53.1 38.6 94.5 33.2 61.6 94.9 142.7 64.2 54.2 153.0 87.0 42.2 36.2 99.3 87.3 42.3 42.6 51.9 35.8 51.5 35.2 36.5 49.9 45.1 128.2 100.7 40.0 35.6 73.1 72.4 89.0 88.3 104.6 102.5 72.3 44.5 32.5 32.8 22.2 56.4 46.9 21.8 71.5 30.7 38.4 18.5 10.1 32.6 11.1 9.3 10.3 8.9 9.0 9.9 8.0 6.9 10.2 8.0 27.4 7.6 10.6 8.0 7.6 8.9 95.4 102.3 106.2 96.8 93.1 99.5 103.5 105.6 106.0 103.6 99.9 112.9 24.4 57.7 37.1 13.1 26.7 51.7 26.5 34.0 35.3 33.3 54.4 38.2 53.2 55.8 34.0 42.3 52.1 44.0 29.1 88.1 35.2 49.4 11.1 24.1 22.8 30.8 38.9 29.8 21.4 37.1 42.8 33.1 37.2 33.9 19.7 34.1 42.1 86.0 31.1 16.8 23.4 51.1 16.2 46.4 52.3 27.7 53.4 25.4 35.6 11.2 64.7 41.6 32.0 11.1 26.3 71.3 44.4 59.5 27.1 57.0 44.7 35.9 23.9 31.6 59.2 31.9 33.2 36.8 25.6 64.7 89.2 88.0 25.0 23.4 42.7 65.8 RAB8A "MEL, RAB8" ENSG00000167461 "RAB8A, member RAS oncogene family" P61006 19 16111889-16134234 "Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041945 Approved "Nucleoplasm,Plasma membrane" No No 4800000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "HPA041945: " "unprognostic (1.10e-1)" "unprognostic (3.95e-3)" "unprognostic (1.98e-2)" "unprognostic (2.59e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (2.11e-1)" "unprognostic (2.57e-1)" "unprognostic (1.14e-2)" "unprognostic (2.52e-3)" "unprognostic (1.29e-2)" "prognostic unfavorable (6.56e-5)" "unprognostic (6.60e-2)" "unprognostic (7.25e-2)" "prognostic favorable (1.71e-4)" "unprognostic (9.99e-2)" 21.3 24.5 17.4 40.4 17.5 61.3 18.7 19.5 17.6 24.6 20.7 37.4 58.5 18.5 18.9 25.9 27.8 22.0 11.5 17.2 19.1 20.8 51.5 28.6 44.3 21.1 19.5 21.5 23.4 17.7 15.3 25.0 21.6 21.7 32.8 8.7 30.7 21.2 7.0 27.5 58.7 22.8 20.3 40.4 32.4 15.4 19.0 34.3 16.3 8.1 45.1 25.9 21.2 23.3 94.2 62.6 50.5 43.0 42.7 36.7 77.9 56.0 48.8 74.2 76.8 76.1 105.7 66.1 61.9 58.6 63.5 60.6 71.2 69.1 50.9 132.6 39.9 135.9 57.1 75.6 46.7 119.4 129.3 36.6 37.6 69.5 32.1 38.9 63.5 65.0 64.4 97.0 63.4 111.6 100.1 113.7 63.3 114.3 100.5 111.6 56.2 115.6 58.2 71.9 46.9 45.3 56.6 68.0 35.9 34.2 53.8 44.2 61.7 61.4 39.2 119.2 96.6 51.4 113.4 97.3 58.7 121.5 67.0 244.5 278.6 315.0 164.3 387.5 145.7 190.5 143.3 147.5 247.5 190.0 112.5 131.7 292.2 225.9 485.1 177.8 150.9 514.1 17.4 17.5 19.5 17.6 17.2 19.1 21.1 19.5 21.6 20.3 19.0 23.3 47.2 25.6 29.1 2.3 70.2 47.7 47.4 53.5 31.3 15.2 37.0 34.7 3.0 17.2 35.7 31.3 14.6 95.7 97.9 115.9 82.2 70.7 31.0 33.7 29.7 37.3 30.4 47.5 4.2 51.5 98.6 36.3 29.6 45.0 48.7 36.2 26.0 50.3 88.9 6.7 3.5 55.3 48.8 50.6 81.5 19.0 27.7 100.9 33.8 2.8 124.8 34.9 131.8 3.0 8.8 76.8 90.0 24.8 96.5 30.7 130.7 62.6 35.4 13.9 32.9 22.0 38.1 33.3 23.4 30.4 52.6 79.6 64.8 43.4 52.0 38.4 RAB8B ENSG00000166128 "RAB8B, member RAS oncogene family" Q92930 15 63189560-63267776 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 81.1" "Cell type enhanced" "Detected in all" "Early spermatids: 220.6;Langerhans cells: 195.6;Late spermatids: 399.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 125.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 4700000 "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (7.67e-2)" "unprognostic (3.33e-2)" "unprognostic (2.75e-1)" "unprognostic (1.32e-1)" "unprognostic (5.20e-2)" "unprognostic (4.01e-2)" "unprognostic (1.46e-2)" "unprognostic (5.94e-2)" "unprognostic (3.19e-1)" "unprognostic (2.75e-2)" "unprognostic (1.71e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.97e-2)" "unprognostic (3.14e-2)" "unprognostic (4.19e-2)" "unprognostic (7.47e-2)" 26.7 14.7 10.6 30.0 12.3 81.1 13.3 11.0 13.1 19.3 14.3 12.5 18.8 17.7 8.4 13.5 10.8 24.4 12.6 12.7 12.2 12.6 15.3 22.4 43.2 10.1 12.3 32.0 7.4 7.7 5.7 30.3 11.5 14.6 11.5 12.0 7.1 10.0 5.4 7.4 17.5 18.7 13.4 34.4 13.2 15.9 13.0 37.8 21.6 10.1 38.9 27.9 9.3 15.3 13.9 12.0 43.4 18.6 82.1 67.0 12.9 13.3 30.3 24.1 46.5 12.7 11.6 38.2 11.8 29.6 26.3 7.0 37.5 18.0 40.8 54.9 7.4 45.4 9.9 8.4 76.1 17.9 28.0 40.8 9.5 45.2 26.7 31.0 60.4 37.1 19.1 36.2 44.3 9.4 27.5 10.3 27.6 12.8 11.2 24.7 57.3 5.6 19.5 66.7 3.8 9.4 20.1 2.8 39.0 27.5 9.4 19.0 68.6 44.8 27.1 24.2 18.2 23.1 24.0 34.6 28.7 50.4 125.5 62.1 26.3 22.4 26.5 23.3 23.6 18.8 20.9 25.9 18.1 17.3 15.8 20.2 56.4 25.0 22.7 2.4 35.7 30.0 10.6 12.3 11.0 13.1 12.7 12.2 10.1 12.3 11.5 13.4 13.0 15.3 32.9 19.2 13.7 18.9 71.8 31.1 7.8 18.8 12.5 2.2 14.8 10.3 5.4 11.5 12.4 7.3 12.5 13.8 140.6 2.4 11.7 37.4 220.6 4.3 28.2 29.5 10.7 19.1 23.7 13.5 102.8 58.9 14.3 8.1 39.3 11.2 33.5 6.6 56.1 20.2 45.4 4.1 14.2 76.9 195.6 399.8 31.7 79.3 35.6 40.3 142.7 13.9 97.9 64.3 62.9 33.3 1.1 38.0 37.6 11.7 11.4 32.8 10.3 14.8 19.7 15.8 29.3 71.3 17.2 7.7 22.4 37.4 105.0 16.3 3.4 22.5 RAC1 "p21-Rac1, Rac-1, TC-25" ENSG00000136238 "Rac family small GTPase 1" P63000 7 6374527-6403967 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 1980.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB035994, HPA047820" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 3900000 "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" Nucleoli "CAB035994: , HPA047820: AB_2680167" "unprognostic (8.66e-3)" "unprognostic (2.47e-1)" "unprognostic (4.00e-1)" "unprognostic (2.40e-2)" "unprognostic (1.88e-3)" "unprognostic (4.06e-2)" "prognostic unfavorable (1.74e-5)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.63e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.95e-1)" "unprognostic (2.11e-2)" "unprognostic (4.13e-2)" "unprognostic (8.72e-3)" 157.4 108.0 237.0 96.8 250.4 94.5 146.4 242.4 290.7 154.8 206.5 190.5 167.4 150.7 149.9 316.9 145.1 125.9 129.4 240.2 240.6 150.5 136.2 147.5 96.4 249.4 244.8 135.8 92.2 151.1 77.5 180.2 249.2 122.8 199.6 52.2 137.9 145.0 179.5 189.2 161.9 179.3 260.2 96.6 160.6 51.6 241.1 115.3 127.2 141.1 169.6 205.3 188.6 262.9 519.9 230.9 233.0 255.1 270.1 341.8 138.6 284.9 348.0 371.6 375.8 227.3 474.8 145.5 179.7 400.9 384.2 359.4 251.5 345.9 471.9 68.3 207.8 146.6 171.7 166.5 323.7 134.0 114.6 229.7 302.8 268.4 297.6 281.7 333.4 141.3 266.2 111.7 406.4 377.3 74.0 312.4 419.1 261.9 272.3 129.2 236.9 214.6 481.7 322.7 175.8 295.9 201.7 726.1 241.4 264.7 409.6 396.3 341.8 242.4 364.3 300.7 334.5 84.1 99.5 135.4 223.9 250.9 470.6 31.0 117.3 63.0 23.8 83.0 15.1 46.8 26.8 30.9 112.8 49.9 33.0 21.8 168.6 26.1 83.5 64.5 46.1 47.0 237.0 250.4 242.4 290.7 240.2 240.6 249.4 244.8 249.2 260.2 241.1 262.9 755.4 147.4 123.6 28.7 155.9 934.1 981.6 232.1 429.2 90.4 485.3 593.8 200.6 484.7 164.8 356.8 25.0 802.8 224.1 920.9 536.1 183.5 77.6 388.7 362.9 641.2 336.7 313.3 43.3 174.2 1064.1 415.9 305.3 422.8 130.9 325.4 580.8 367.1 832.0 146.4 35.3 632.9 179.0 811.3 1066.7 58.8 476.3 705.7 458.9 66.5 607.2 341.1 191.6 23.1 56.7 299.1 754.4 472.8 212.2 1495.5 816.4 832.0 214.1 64.2 479.9 346.6 466.6 216.6 373.1 774.5 1148.6 845.4 180.0 353.6 573.7 1980.7 RACGAP1 MgcRacGAP ENSG00000161800 "Rac GTPase activating protein 1" Q9H0H5 12 49976923-50033136 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.9;lymphoid tissue: 43.0;testis: 45.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 55.7;Extravillous trophoblasts: 49.4;Spermatocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025859, HPA039427, HPA043912" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB025859: , HPA039427: AB_2676503, HPA043912: AB_2678728" "prognostic unfavorable (1.51e-4)" "unprognostic (1.91e-1)" "unprognostic (3.74e-3)" "unprognostic (1.53e-2)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.86e-6)" "unprognostic (1.15e-3)" "unprognostic (3.07e-3)" "unprognostic (5.31e-2)" "prognostic unfavorable (4.12e-6)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.98e-8)" "unprognostic (3.13e-2)" "unprognostic (4.94e-1)" "unprognostic (6.16e-2)" "unprognostic (2.15e-1)" 5.0 2.5 5.5 13.7 8.2 38.9 7.1 6.9 6.3 5.2 3.2 16.7 10.5 5.3 1.5 21.3 4.4 6.4 2.8 5.0 6.0 9.2 4.7 6.2 23.9 6.7 7.1 2.4 2.7 5.8 1.4 14.0 6.5 3.3 18.7 5.3 4.8 3.4 4.9 14.4 11.6 12.5 5.5 6.5 9.8 45.5 7.6 43.0 3.3 4.8 30.2 7.7 8.0 7.0 193.0 174.5 135.8 86.8 24.8 29.7 113.0 195.0 97.0 207.3 140.3 174.6 144.7 107.5 86.0 108.3 99.9 127.1 137.7 93.6 219.9 203.0 85.4 137.9 165.8 58.1 8.4 146.1 109.0 16.2 17.2 140.7 111.4 60.3 71.7 96.4 101.6 159.6 197.0 136.8 122.5 72.6 96.2 108.9 112.9 113.9 163.5 78.3 54.9 95.7 113.9 97.5 161.7 102.7 53.0 68.8 199.7 64.8 64.9 136.2 119.1 86.8 144.7 83.3 225.2 126.6 67.7 97.0 81.1 24.1 3.2 4.7 6.5 4.1 5.7 8.2 7.9 9.2 2.8 4.3 4.6 6.1 0.7 11.0 2.6 1.8 19.1 5.8 5.5 8.2 6.9 6.3 5.0 6.0 6.7 7.1 6.5 5.5 7.6 7.0 2.0 6.4 6.4 2.9 4.2 12.9 2.5 4.9 6.2 1.5 4.8 5.1 1.5 2.8 3.3 5.5 4.2 21.8 4.4 3.1 19.6 1.9 15.2 2.2 3.1 2.7 0.0 55.7 7.5 2.2 49.4 5.9 7.7 4.0 2.5 14.2 5.3 2.7 13.1 1.7 8.0 5.7 20.3 11.3 8.0 17.7 1.5 7.1 1.8 1.0 4.5 2.7 6.2 6.0 12.3 2.0 1.0 3.8 10.9 2.8 1.1 2.1 2.3 0.8 13.1 3.1 5.5 79.6 32.2 19.5 12.9 8.6 6.9 2.2 11.6 2.9 RAD23B "HHR23B, HR23B, P58" ENSG00000119318 "RAD23 homolog B, nucleotide excision repair protein" P54727 9 107283137-107332192 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 420.5;Late spermatids: 1201.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029718, HPA029720, CAB033868" Enhanced Supported Nucleoplasm,Cytosol No No 5900000 "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "CAB033868: AB_1128418, HPA029718: AB_10600116, HPA029720: AB_10601008" "unprognostic (3.95e-3)" "unprognostic (1.01e-2)" "unprognostic (2.28e-2)" "unprognostic (8.14e-2)" "unprognostic (4.71e-2)" "prognostic unfavorable (2.58e-4)" "unprognostic (2.94e-1)" "prognostic unfavorable (6.71e-4)" "unprognostic (1.34e-1)" "unprognostic (3.72e-1)" "unprognostic (3.31e-2)" "unprognostic (1.20e-1)" "unprognostic (2.94e-3)" "unprognostic (2.69e-2)" "unprognostic (2.43e-1)" "unprognostic (7.49e-3)" "unprognostic (1.04e-1)" 73.8 47.8 26.6 44.4 27.0 82.8 48.5 40.4 37.4 42.8 22.0 47.7 41.9 41.9 68.8 63.6 40.9 34.1 48.7 29.0 29.2 44.4 140.8 39.3 39.4 26.9 27.0 37.8 64.5 50.4 30.5 77.7 26.3 48.2 47.7 42.1 38.4 43.5 153.0 64.7 40.6 55.0 22.5 36.2 41.5 59.4 27.7 58.4 42.6 123.5 49.9 67.5 42.8 30.7 132.9 114.9 158.6 102.9 107.5 166.6 179.9 200.6 162.3 172.8 116.9 190.1 140.5 184.8 79.3 218.6 156.4 181.2 221.0 175.9 172.9 126.4 73.0 96.2 112.0 147.6 140.3 174.2 79.3 141.1 161.3 165.3 248.0 136.0 124.3 79.6 158.3 133.6 159.5 215.0 169.6 88.3 170.5 231.2 133.0 125.3 209.6 87.8 149.8 122.1 144.9 98.2 138.8 193.1 125.8 237.5 197.7 70.5 114.3 129.0 127.0 161.6 152.5 91.9 181.2 98.5 138.0 101.7 138.0 0.9 1.1 1.1 1.9 1.2 2.1 1.8 1.1 1.6 1.0 2.1 1.7 1.5 2.9 2.3 0.8 1.1 2.2 0.6 26.6 27.0 40.4 37.4 29.0 29.2 26.9 27.0 26.3 22.5 27.7 30.7 49.7 44.8 40.4 32.3 54.7 195.5 148.1 40.5 79.1 40.5 65.3 36.6 117.4 68.6 42.2 35.0 27.1 269.7 37.1 82.9 50.9 89.2 420.5 69.8 80.8 68.7 101.0 76.1 54.9 77.4 259.7 79.3 60.6 90.8 36.2 83.0 55.6 209.9 99.5 50.5 47.2 83.8 38.7 65.6 131.1 1201.4 75.5 70.7 74.7 38.4 83.7 40.4 39.1 50.3 54.1 81.0 50.5 87.3 89.3 146.0 51.2 95.9 47.6 43.9 78.9 71.6 88.5 45.3 74.7 126.9 240.9 291.8 50.5 91.1 74.9 141.2 RAD51 "BRCC5, FANCR, HsRad51, HsT16930, RAD51A, RECA" ENSG00000051180 "RAD51 recombinase" Q06609 15 40694774-40732340 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.7;testis: 24.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Extravillous trophoblasts: 67.2;Spermatocytes: 53.6;Spermatogonia: 24.8;Syncytiotrophoblasts: 25.3" "Cancer enhanced" "Detected in all" "testis cancer: 19.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010381, HPA039310" Enhanced Supported "Nucleoli rim,Cytosol" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoli rim" Cytosol "CAB010381: AB_2253533, HPA039310: AB_2676434" "prognostic unfavorable (7.94e-4)" "unprognostic (7.20e-3)" "unprognostic (1.22e-1)" "unprognostic (2.72e-2)" "unprognostic (8.23e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-3)" "unprognostic (2.53e-3)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (2.34e-1)" "unprognostic (9.59e-2)" "unprognostic (1.94e-2)" 0.9 0.6 0.4 5.5 0.5 10.5 1.9 1.7 0.7 1.0 0.6 8.3 3.2 1.2 0.4 4.2 0.7 1.3 0.6 0.4 0.5 0.5 1.3 1.1 11.0 0.4 0.3 0.6 1.4 0.5 0.2 6.8 0.5 0.8 9.1 0.3 1.0 0.3 1.0 3.1 4.1 2.4 0.1 2.4 1.8 24.3 0.3 15.7 0.6 0.5 13.3 1.7 1.5 0.5 33.8 16.1 33.4 16.3 4.4 7.8 31.1 54.9 16.5 43.3 43.8 35.4 22.1 20.4 26.8 20.9 18.9 67.7 56.6 22.1 42.3 39.0 22.2 47.7 28.2 30.4 0.4 37.9 28.5 1.7 2.9 30.0 13.5 6.4 22.5 48.5 59.6 55.8 36.6 28.5 54.4 43.6 35.2 69.2 19.0 61.0 49.0 30.7 15.4 45.3 15.4 27.0 23.6 41.4 8.5 39.2 27.0 39.4 9.9 32.8 22.2 48.7 27.2 12.0 65.1 59.8 16.3 78.0 33.5 1.3 0.6 1.7 2.4 1.3 0.6 1.7 2.5 3.2 1.0 1.1 0.6 1.2 1.2 1.8 1.4 0.9 5.9 1.2 0.4 0.5 1.7 0.7 0.4 0.5 0.4 0.3 0.5 0.1 0.3 0.5 0.0 0.0 0.0 0.3 1.9 3.6 1.5 2.0 0.0 0.8 0.1 0.0 0.9 0.0 1.0 0.0 0.0 35.3 1.4 3.0 0.0 0.0 5.7 0.2 0.2 1.0 0.0 16.0 1.6 0.0 67.2 1.3 2.0 0.2 0.0 0.6 2.2 0.2 12.7 0.0 1.2 5.3 2.0 1.6 1.7 5.3 0.6 0.5 0.0 1.0 0.3 0.3 2.1 0.5 0.6 0.1 5.0 0.7 8.2 0.9 1.0 0.0 0.1 0.0 0.0 0.5 0.9 53.6 24.8 3.9 1.6 25.3 1.2 0.1 8.0 2.1 RAD51AP1 PIR51 ENSG00000111247 "RAD51 associated protein 1" Q96B01 12 4538798-4560047 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Meiosis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.9;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in many" "Early spermatids: 33.4;Erythroid cells: 47.8;Extravillous trophoblasts: 34.1;Hofbauer cells: 40.8;Late spermatids: 68.1;Spermatocytes: 35.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051499 Approved Nucleoplasm Yes Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA051499: AB_2681508" "unprognostic (1.03e-1)" "unprognostic (5.44e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (6.30e-2)" "unprognostic (5.25e-3)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.15e-2)" "unprognostic (2.26e-2)" "unprognostic (6.29e-3)" "prognostic unfavorable (1.22e-5)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.44e-15)" "unprognostic (2.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.88e-2)" "unprognostic (3.75e-2)" 0.9 0.8 0.3 4.8 0.4 16.9 2.7 0.4 0.7 0.9 0.3 5.2 5.2 1.2 0.6 3.2 1.0 1.1 0.5 0.3 0.3 0.8 1.8 1.4 8.9 0.4 0.4 0.5 0.4 0.6 0.3 3.8 0.4 1.3 6.5 1.5 1.0 1.0 0.5 3.2 4.8 1.9 0.4 3.4 2.7 6.3 0.4 14.4 1.0 0.6 7.9 1.7 1.3 0.5 37.5 13.0 45.3 22.7 2.7 5.7 53.0 48.2 21.2 52.6 68.9 35.4 35.4 48.6 7.0 10.4 24.7 23.1 31.8 14.5 80.0 38.7 27.0 61.4 21.6 24.8 0.6 56.6 29.9 1.2 1.5 31.6 30.4 7.5 21.4 33.0 39.2 54.4 33.7 13.6 46.5 20.5 110.4 36.3 14.4 46.0 54.3 19.2 16.1 18.3 15.1 16.6 35.9 27.7 11.6 45.5 11.3 32.6 9.5 35.5 36.5 38.8 52.4 7.8 10.0 93.3 13.3 40.0 29.4 0.0 0.5 0.7 0.1 2.3 0.5 3.1 0.4 1.0 0.4 3.4 0.1 0.2 0.0 1.4 2.0 6.9 1.0 0.6 0.3 0.4 0.4 0.7 0.3 0.3 0.4 0.4 0.4 0.4 0.4 0.5 1.4 0.0 0.5 0.7 6.1 5.2 2.3 6.6 1.2 3.1 3.4 5.7 1.4 2.8 4.5 0.0 4.2 20.3 11.3 5.7 0.0 3.0 33.4 3.3 2.9 2.9 2.4 47.8 2.7 2.7 34.1 5.2 6.1 3.6 1.3 22.6 2.5 1.2 40.8 0.0 1.1 6.4 16.2 6.2 5.6 68.1 1.2 10.1 0.0 3.7 6.8 2.7 3.1 0.5 2.4 1.5 0.8 1.5 15.5 1.0 1.2 1.5 0.9 4.8 0.0 2.4 4.2 35.9 25.0 10.0 2.6 4.7 4.6 2.0 14.6 2.7 RAD54L "hHR54, hRAD54, RAD54A" ENSG00000085999 "RAD54 like" Q92698 1 46246461-46278480 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.4;testis: 15.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 7.2;Extravillous trophoblasts: 9.4;Glandular and luminal cells: 8.0;Spermatocytes: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028954, HPA051537" Approved Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA028954: AB_2672840, HPA051537: AB_2681525" "unprognostic (2.12e-2)" "prognostic favorable (6.67e-4)" "unprognostic (5.12e-2)" "unprognostic (5.36e-3)" "unprognostic (3.24e-1)" "unprognostic (1.08e-2)" "unprognostic (9.75e-6)" "unprognostic (3.91e-2)" "unprognostic (2.17e-3)" "unprognostic (2.95e-2)" "unprognostic (1.77e-4)" "unprognostic (5.58e-2)" "unprognostic (1.11e-16)" "unprognostic (6.76e-3)" "unprognostic (1.66e-1)" "unprognostic (2.67e-1)" "unprognostic (1.74e-1)" 0.5 0.7 3.0 4.1 3.8 8.7 1.0 4.3 3.9 1.3 2.1 3.2 2.0 0.7 0.1 5.4 0.4 0.5 0.7 2.9 2.5 1.4 0.5 1.2 5.5 3.2 3.0 0.5 0.5 0.3 0.4 3.4 3.8 1.0 4.6 0.4 0.9 0.4 1.2 2.3 2.8 1.7 2.8 2.8 1.5 15.6 3.1 15.4 1.8 0.0 8.3 0.8 1.8 3.7 22.2 16.1 46.8 29.1 3.3 2.4 43.9 25.8 11.3 42.8 43.3 33.3 14.2 42.5 19.1 11.0 38.5 22.2 44.6 14.5 36.8 23.7 43.0 53.0 49.7 32.1 0.1 54.0 29.3 1.6 1.2 42.1 12.5 6.9 13.5 49.7 38.2 41.7 23.1 20.4 68.9 60.0 42.5 19.4 25.2 52.8 26.8 19.0 9.4 17.5 22.4 16.3 18.4 25.2 5.7 38.0 9.1 37.7 5.7 43.9 26.1 23.6 43.7 17.6 10.6 46.9 11.5 35.1 18.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.2 3.0 3.8 4.3 3.9 2.9 2.5 3.2 3.0 3.8 2.8 3.1 3.7 0.0 0.0 0.0 1.0 0.7 0.3 0.7 0.5 1.8 0.0 0.5 0.5 0.8 0.0 0.1 0.0 0.0 4.3 0.4 1.8 0.0 0.3 2.7 2.3 0.8 0.5 0.0 7.2 2.8 0.0 9.4 1.1 0.5 8.0 4.5 5.6 0.4 0.0 2.6 0.0 1.1 1.3 0.0 0.3 0.3 0.7 0.0 0.4 0.0 0.0 0.0 0.0 1.0 1.0 2.9 0.3 0.1 0.0 4.7 0.4 0.4 0.0 0.1 0.0 0.0 0.4 4.0 12.4 5.6 3.1 0.3 1.6 1.1 0.2 2.9 1.0 RAE1 "Gle2, Mnrp41" ENSG00000101146 "Ribonucleic acid export 1" P78406 20 57351223-57379211 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 103.0" "Cell type enhanced" "Detected in all" "Early spermatids: 113.6;Spermatocytes: 256.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048795 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli fibrillar center" "HPA048795: AB_2680523" "unprognostic (1.20e-1)" "unprognostic (5.98e-2)" "unprognostic (4.55e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (3.23e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (2.12e-7)" "unprognostic (1.88e-1)" "unprognostic (8.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.50e-3)" "unprognostic (3.88e-2)" "unprognostic (7.48e-2)" "unprognostic (3.55e-1)" "unprognostic (9.49e-2)" "unprognostic (2.89e-1)" "unprognostic (2.01e-1)" 14.0 13.9 18.6 13.5 19.1 50.5 17.0 18.5 19.1 15.5 17.6 14.2 11.9 16.6 18.2 20.5 17.4 9.0 13.3 18.3 19.9 14.1 16.5 10.0 20.8 16.3 15.9 16.3 10.8 19.1 13.3 14.6 17.0 12.4 16.2 20.1 12.8 15.0 15.0 22.9 13.6 16.3 17.2 17.0 12.8 103.0 21.4 29.2 12.1 15.8 26.5 14.5 16.0 19.6 43.5 52.6 52.8 29.3 30.1 29.0 46.1 33.9 47.2 172.2 70.3 166.1 33.8 69.2 46.8 52.8 63.8 56.6 101.6 88.3 142.1 20.8 45.2 47.0 46.0 74.9 59.0 57.1 41.3 41.3 74.0 75.8 83.1 29.1 49.9 47.2 84.8 32.5 53.0 114.8 88.3 53.2 32.9 86.3 93.3 47.6 49.4 46.0 37.3 45.5 55.2 47.6 58.4 129.4 61.0 41.2 71.5 54.0 29.7 70.6 63.0 41.7 57.7 34.9 83.9 81.8 48.3 36.1 35.6 21.2 42.0 77.0 27.0 36.8 32.9 31.2 26.0 26.8 32.3 28.1 33.9 30.7 36.2 24.7 37.9 23.8 24.6 40.4 18.6 19.1 18.5 19.1 18.3 19.9 16.3 15.9 17.0 17.2 21.4 19.6 17.5 19.2 16.7 8.5 21.0 17.2 16.3 42.0 15.9 15.9 12.6 19.3 10.4 11.5 24.1 18.4 14.6 52.8 20.8 11.6 27.4 30.3 113.6 16.5 16.7 17.9 6.6 18.7 10.2 14.3 39.3 18.6 12.2 15.3 38.0 25.6 11.0 13.5 38.3 3.3 9.5 15.2 18.3 59.5 14.5 63.9 21.8 33.5 10.6 14.0 40.0 19.9 27.8 5.5 13.1 22.2 24.3 22.6 15.9 14.0 10.1 20.6 24.1 17.9 19.7 11.6 19.9 256.9 83.1 19.2 21.0 70.5 24.2 34.9 20.1 16.2 RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883375-149898102 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 21.9;esophagus: 62.8;skin 1: 21.6;vagina: 27.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 12.4;Early spermatids: 10.0;Late spermatids: 5.6;Respiratory ciliated cells: 14.6;Squamous epithelial cells: 17.2;Suprabasal keratinocytes: 6.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 19.6;HeLa: 24.4;hTCEpi: 19.1;SiHa: 9.9;U-87 MG: 7.7" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Focal adhesion sites" Cytosol "HPA054022: AB_2797250" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (1.36e-3)" "unprognostic (4.80e-4)" "unprognostic (1.11e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (7.47e-5)" "unprognostic (2.41e-2)" "unprognostic (3.18e-2)" "unprognostic (3.17e-2)" "unprognostic (1.06e-1)" 3.7 0.8 0.6 0.1 0.4 0.1 1.9 1.0 0.7 21.9 0.8 0.2 0.1 0.3 0.0 62.8 0.8 0.1 0.5 0.5 0.5 2.2 0.1 0.3 0.1 0.4 0.3 0.1 0.1 0.0 0.2 0.5 0.5 0.3 0.3 0.1 12.9 0.3 1.6 21.6 0.1 0.5 0.1 0.9 0.3 0.4 0.4 0.1 0.3 0.2 11.6 1.9 27.5 0.5 1.8 1.0 0.0 0.0 0.2 1.3 0.0 0.1 0.9 0.1 0.3 0.0 4.3 0.0 2.6 4.4 1.4 1.7 0.0 19.6 0.2 0.3 0.0 0.1 24.4 0.0 0.0 0.0 0.0 0.4 19.1 1.0 3.9 0.4 0.1 0.1 0.0 1.3 0.8 0.0 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.3 0.4 0.9 0.2 0.0 9.9 1.5 0.0 0.0 1.2 0.0 1.8 0.8 0.3 0.2 0.9 0.0 0.0 0.0 7.7 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 1.0 0.7 0.5 0.5 0.4 0.3 0.5 0.1 0.4 0.5 1.0 0.0 0.0 0.3 0.0 2.2 1.1 12.4 1.8 0.6 0.3 0.6 0.3 1.5 3.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 2.5 0.1 1.0 0.0 0.0 0.9 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 1.1 0.1 0.0 0.0 0.3 5.6 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.5 1.1 0.4 0.0 0.0 0.0 0.2 0.0 0.0 14.6 0.4 0.0 0.3 0.4 0.0 0.2 17.2 6.5 0.0 0.2 0.1 0.2 1.6 RAMP2 ENSG00000131477 "Receptor activity modifying protein 2" O60895 17 42758447-42763041 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 1066.8;Endothelial cells: 562.9;Hepatic stellate cells: 344.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 21 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "ASC diff: 120.4;EFO-21: 80.5;HUVEC TERT2: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052020 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA052020: AB_2681697" "unprognostic (8.64e-2)" "unprognostic (2.12e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (6.79e-2)" "unprognostic (1.28e-2)" "unprognostic (6.96e-3)" "unprognostic (4.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" 190.0 29.0 60.4 19.2 61.8 0.1 168.9 61.7 72.3 100.7 67.7 35.7 12.5 63.1 27.8 25.1 51.7 39.6 123.2 59.3 65.8 70.5 16.7 163.3 26.2 65.7 68.1 33.0 17.1 23.8 20.8 97.0 72.7 42.1 21.1 4.1 45.9 27.5 43.3 55.9 44.1 72.6 62.7 40.2 33.9 11.9 66.6 11.4 71.7 98.7 24.5 45.9 49.6 62.4 0.1 1.1 4.9 0.1 120.4 6.2 4.0 0.9 2.1 10.2 4.9 11.5 0.1 0.0 80.5 3.0 0.5 0.0 4.6 0.1 8.9 0.0 0.2 0.0 0.7 3.7 3.0 0.0 0.0 4.2 0.1 1.8 0.4 3.5 37.6 1.5 0.1 0.2 0.6 0.0 0.6 0.8 23.3 0.0 0.0 0.1 0.1 0.0 0.6 0.6 4.8 9.8 2.9 0.0 17.3 4.8 1.2 3.2 6.7 19.3 7.1 0.4 2.4 0.0 0.1 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 60.4 61.8 61.7 72.3 59.3 65.8 65.7 68.1 72.7 62.7 66.6 62.4 1066.8 0.0 5.7 1.6 6.2 34.4 5.4 0.9 9.6 0.6 24.0 24.8 2.2 0.0 1.0 3.7 0.0 1.1 3.7 0.1 3.9 0.6 1.6 22.2 52.8 562.9 4.2 0.0 0.2 0.7 1.7 126.9 3.1 38.5 0.0 1.4 344.8 1.3 3.4 0.0 1.0 0.2 20.3 8.4 40.5 3.6 38.8 4.1 23.2 45.0 2.6 15.5 0.0 1.5 0.3 0.0 0.0 21.8 5.2 4.8 0.0 1.0 0.1 1.8 6.6 10.5 26.3 26.6 59.1 2.6 27.6 1.5 4.0 14.0 0.1 4.3 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RAP1GAP "KIAA0474, RAP1GA1, RAP1GAP1, RAP1GAPII" ENSG00000076864 "RAP1 GTPase activating protein" P47736 1 21596215-21669363 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 152.4;thyroid gland: 162.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 64.1;Distal tubular cells: 72.4;Excitatory neurons: 82.0;Horizontal cells: 92.5;Intestinal goblet cells: 112.6;Oligodendrocyte precursor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 46.3;OE19: 162.8;SCLC-21H: 52.1" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 231.1" "HPA001922, CAB003851" Enhanced Supported Approved Cytosol NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "CAB003851: AB_562338, HPA001922: AB_1079743" "unprognostic (1.17e-2)" "unprognostic (4.33e-2)" "unprognostic (7.84e-2)" "unprognostic (2.45e-2)" "unprognostic (4.52e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (8.33e-2)" "unprognostic (1.52e-2)" "unprognostic (2.35e-1)" "unprognostic (3.43e-2)" "unprognostic (1.35e-2)" "prognostic favorable (1.12e-6)" "unprognostic (1.11e-1)" "unprognostic (9.85e-3)" "unprognostic (4.86e-3)" "unprognostic (3.64e-2)" 0.6 80.8 74.0 2.6 118.6 0.8 4.4 24.6 91.9 7.5 0.0 19.7 12.4 1.9 1.9 7.5 4.2 24.9 9.5 76.2 34.5 152.4 36.1 14.2 1.0 35.8 22.0 1.6 106.2 57.1 37.9 2.1 32.8 12.8 17.3 27.3 88.7 0.8 0.2 3.5 21.7 0.7 15.8 1.2 110.8 3.6 32.4 0.5 162.8 0.3 0.9 4.0 3.4 67.3 6.2 46.3 0.5 3.6 0.0 0.0 0.8 0.0 0.1 0.1 0.0 4.3 6.4 0.1 4.6 0.2 30.2 7.9 4.4 0.3 0.1 1.0 2.3 2.2 4.3 22.1 0.7 0.0 6.6 0.3 3.1 0.0 0.0 0.0 0.0 22.1 29.6 1.1 0.0 15.6 7.7 0.7 2.8 162.8 7.0 4.3 1.2 1.1 10.2 3.4 52.1 9.3 7.7 27.4 8.9 1.8 2.7 5.2 0.1 0.0 3.1 0.0 0.1 0.6 0.1 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.0 118.6 24.6 91.9 76.2 34.5 35.8 22.0 32.8 15.8 32.4 67.3 0.0 9.6 29.3 10.4 0.5 1.3 1.1 1.1 0.6 64.1 8.5 5.6 5.1 25.8 4.5 14.7 0.0 0.2 0.1 4.3 72.4 25.1 0.8 3.1 0.6 0.4 6.7 4.0 82.0 28.8 1.4 1.0 17.3 8.0 0.0 6.2 0.4 8.5 0.3 92.5 45.8 112.6 6.1 0.6 0.3 0.3 0.0 0.6 16.0 3.7 0.6 11.5 0.0 51.8 18.6 15.3 17.2 0.0 0.2 5.0 6.0 13.5 1.2 7.3 0.0 0.0 0.7 1.0 3.6 0.5 1.1 1.5 0.3 2.5 7.7 2.6 RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734363-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 130.6;Astrocytes: 143.0;Collecting duct cells: 69.9;Endothelial cells: 53.0;Oligodendrocytes: 45.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 26.9;HUVEC TERT2: 12.1;NB-4: 14.3;RPTEC TERT1: 13.3;TIME: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Endoplasmic reticulum" "CAB004386: AB_627521, HPA040365: AB_2676941, HPA043518: AB_2678524" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (2.99e-2)" "unprognostic (1.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-4)" "unprognostic (9.35e-2)" "unprognostic (1.25e-2)" "unprognostic (5.32e-3)" "unprognostic (4.67e-2)" "unprognostic (4.37e-2)" "prognostic favorable (6.67e-7)" "unprognostic (9.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.61e-3)" "unprognostic (3.38e-2)" 44.6 2.8 29.2 2.6 35.0 1.4 44.0 30.3 29.2 26.0 12.5 9.9 4.0 16.4 6.9 13.2 24.1 13.2 21.1 31.4 21.3 40.0 1.9 11.9 4.4 33.6 29.6 38.2 4.7 5.8 6.4 8.9 28.0 13.5 2.4 0.9 21.2 11.0 11.4 9.8 8.8 5.1 22.4 16.2 11.5 3.5 28.9 1.6 32.4 9.0 2.1 14.9 21.3 39.7 2.3 0.6 0.7 2.4 0.3 2.3 0.9 1.7 1.5 0.7 0.4 0.3 6.1 0.1 26.9 3.0 1.1 2.4 0.8 4.5 0.3 3.0 0.4 0.2 2.6 0.2 0.2 0.4 0.3 0.9 0.3 1.3 0.8 3.4 12.1 0.6 0.1 2.9 0.5 1.5 0.0 14.3 0.6 1.0 3.7 0.4 0.1 1.0 13.3 2.5 0.2 0.3 0.2 1.7 0.4 0.8 6.7 0.6 12.0 6.6 1.1 1.5 0.6 1.0 0.4 0.2 4.1 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 35.0 30.3 29.2 31.4 21.3 33.6 29.6 28.0 22.4 28.9 39.7 130.6 0.0 11.7 143.0 0.7 2.7 5.8 2.6 13.1 0.5 4.5 4.8 15.7 2.8 3.6 69.9 0.0 0.2 1.4 1.7 7.9 1.1 1.6 11.8 2.4 53.0 0.0 0.0 1.5 0.7 0.4 6.3 18.3 21.2 3.8 1.5 20.7 0.2 0.9 0.0 2.9 6.6 4.1 0.6 2.6 3.7 24.2 1.5 5.4 12.2 0.0 1.5 2.1 10.6 45.7 5.8 6.3 8.6 4.4 11.6 0.8 41.3 1.9 0.5 6.6 2.7 5.1 1.2 1.6 1.4 3.3 0.3 1.3 6.6 0.8 17.2 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 199.1;skin 1: 237.7;vagina: 113.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.7;Excitatory neurons: 47.8;Proximal enterocytes: 55.3;Squamous epithelial cells: 95.4;Suprabasal keratinocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HaCaT: 92.4;hTCEpi: 45.8;T-47d: 80.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: AB_1856071" "prognostic favorable (8.43e-4)" "prognostic favorable (3.28e-4)" "unprognostic (1.61e-1)" "unprognostic (1.13e-2)" "unprognostic (4.64e-3)" "unprognostic (3.48e-2)" "unprognostic (5.92e-2)" "unprognostic (1.80e-1)" "unprognostic (3.64e-2)" "unprognostic (2.67e-1)" "unprognostic (7.46e-3)" "unprognostic (8.84e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" 6.3 4.4 38.4 6.8 36.1 4.4 9.1 12.1 58.3 48.7 1.8 53.8 48.3 4.6 9.9 199.1 6.6 8.8 6.8 55.1 12.9 3.8 10.5 8.0 2.2 12.0 11.4 3.7 7.9 1.1 14.2 2.3 10.9 17.7 44.5 6.1 27.4 6.9 12.6 237.7 40.6 4.0 8.3 7.3 31.8 10.2 15.2 3.3 4.5 2.8 20.7 21.9 113.2 30.6 5.3 2.6 13.7 10.2 1.5 3.3 6.6 1.9 1.4 2.7 3.2 6.0 7.6 4.2 1.9 2.7 2.4 92.4 2.7 3.3 3.8 7.7 6.9 2.5 3.6 6.0 1.7 5.2 8.5 3.9 45.8 2.8 1.3 4.0 4.1 13.9 1.9 2.8 2.1 14.6 4.9 6.3 4.3 26.1 2.6 8.8 1.6 2.6 1.7 27.6 26.2 5.3 3.3 31.2 1.3 11.5 80.7 3.9 7.9 3.3 6.8 3.5 3.2 4.6 4.7 3.4 7.8 3.2 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 38.4 36.1 12.1 58.3 55.1 12.9 12.0 11.4 10.9 8.3 15.2 30.6 1.9 0.0 1.1 7.5 1.0 45.5 9.7 14.0 13.1 5.7 2.6 3.7 2.4 11.5 10.9 1.8 6.2 0.2 0.7 87.7 0.0 0.9 2.7 5.9 2.1 2.2 4.9 2.7 47.8 0.8 0.3 1.4 32.6 9.4 5.7 1.7 3.9 4.4 0.5 1.7 32.1 31.9 6.1 1.2 5.2 2.2 3.4 1.9 5.4 1.0 2.4 2.9 1.0 8.0 5.0 1.6 44.6 3.8 0.1 10.9 55.3 0.1 6.5 4.4 0.0 2.1 1.9 12.0 15.0 95.4 97.0 0.7 1.1 1.8 44.1 39.2 RARG "NR1B3, RARC" ENSG00000172819 "Retinoic acid receptor gamma" P13631 12 53210567-53232980 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 141.6;skin 1: 121.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 42.7;Squamous epithelial cells: 69.9;Suprabasal keratinocytes: 55.8;Urothelial cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.8" "Group enriched" "Detected in all" 4 "dendritic cells: 6.7;T-cells: 18.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 101.0;MCF7: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053883 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA053883: AB_2682292" "unprognostic (7.29e-2)" "unprognostic (1.95e-2)" "unprognostic (6.11e-2)" "prognostic unfavorable (3.68e-6)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" "unprognostic (2.28e-1)" "unprognostic (1.08e-2)" "unprognostic (3.54e-3)" "unprognostic (7.21e-3)" "unprognostic (3.78e-3)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (5.41e-3)" "unprognostic (1.98e-2)" "unprognostic (5.94e-3)" "unprognostic (7.41e-2)" 17.4 16.2 10.2 5.7 9.7 3.7 19.4 13.0 10.9 55.0 10.8 22.7 2.5 23.3 6.0 141.6 27.2 15.7 17.3 9.7 9.5 12.5 3.2 15.2 5.9 10.3 10.0 20.5 8.5 7.2 8.7 9.5 9.3 26.9 7.8 3.9 30.6 16.2 6.9 121.4 10.4 13.0 10.0 10.2 14.5 4.8 9.5 5.1 22.6 10.6 22.5 26.2 69.3 10.0 22.8 24.7 5.5 50.9 55.0 46.8 1.7 23.2 50.0 29.7 23.3 8.3 101.0 0.5 12.5 93.6 16.2 74.3 18.4 44.6 7.4 5.7 9.4 3.3 18.6 7.4 23.2 0.0 9.1 34.8 63.9 28.5 6.4 74.7 12.7 4.6 0.8 9.8 11.9 110.3 1.3 1.1 16.3 30.4 42.7 7.3 1.9 18.1 8.9 37.1 4.4 22.9 47.0 50.6 32.1 6.8 43.9 1.4 13.8 35.4 16.5 23.6 1.5 4.2 2.6 1.8 43.4 3.8 51.3 1.8 3.1 0.9 7.4 0.9 18.8 2.0 6.5 5.4 6.7 0.6 5.2 4.7 0.0 2.3 0.0 0.6 1.8 4.0 10.2 9.7 13.0 10.9 9.7 9.5 10.3 10.0 9.3 10.0 9.5 10.0 10.7 3.2 7.0 21.2 2.5 34.2 24.1 21.6 42.7 0.5 18.0 15.6 3.7 11.5 11.1 3.7 2.1 7.5 6.2 3.2 0.0 10.5 0.1 3.6 14.4 11.0 1.8 0.8 2.5 5.1 1.2 19.6 13.7 3.4 1.3 0.3 20.3 0.1 2.7 0.0 3.0 2.1 12.2 4.1 13.3 0.5 5.3 4.9 8.8 6.5 1.8 3.6 5.2 7.1 0.7 14.3 4.4 5.3 3.0 19.2 0.2 0.5 3.9 5.2 6.6 9.5 22.0 0.8 5.6 69.9 55.8 1.8 7.2 0.4 5.5 45.7 RARRES1 "LXNL, TIG1" ENSG00000118849 "Retinoic acid receptor responder 1" P49788 3 158696892-158732489 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 221.9;fallopian tube: 206.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 217.1;Club cells: 621.4;Prostatic glandular cells: 312.9;Urothelial cells: 737.7" "Cancer enhanced" "Detected in all" "urothelial cancer: 93.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 10 "CAPAN-2: 1319.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003892 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "Endoplasmic reticulum" "HPA003892: AB_1856079" "unprognostic (5.76e-3)" "unprognostic (2.13e-1)" "unprognostic (8.85e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.09e-2)" "unprognostic (8.93e-2)" "unprognostic (3.86e-1)" "unprognostic (7.16e-3)" "unprognostic (1.47e-2)" "unprognostic (6.42e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.88e-6)" "unprognostic (3.49e-1)" "unprognostic (1.33e-1)" "unprognostic (7.73e-2)" "unprognostic (1.15e-1)" 221.9 21.3 1.0 65.1 1.5 0.6 44.6 1.5 1.7 74.6 11.3 31.7 5.1 25.9 27.0 11.3 206.4 19.7 81.5 1.5 0.8 25.1 4.2 52.7 18.9 0.6 0.4 60.5 10.0 0.2 27.7 3.5 0.4 78.6 36.2 0.9 165.3 37.2 5.6 8.3 38.5 51.2 0.4 2.7 23.7 4.5 1.0 1.8 20.4 2.8 6.2 92.1 32.2 1.4 19.2 6.9 0.2 1.0 4.0 12.6 0.3 1.8 5.7 1.0 1.4 1.4 1319.3 0.0 1.2 0.9 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.0 0.1 12.0 0.0 0.0 131.3 0.0 0.5 0.0 8.9 2.8 0.0 0.0 0.0 0.4 0.0 0.0 0.2 1.7 5.8 0.0 0.0 0.0 0.1 0.3 22.9 0.5 1.7 16.7 1.3 0.3 0.0 1.9 2.3 1.3 1.1 0.0 4.6 0.0 0.0 0.0 0.0 1.5 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.0 1.5 1.5 1.7 1.5 0.8 0.6 0.4 0.4 0.4 1.0 1.4 5.2 0.0 0.6 2.3 0.9 0.5 217.1 92.7 11.4 0.4 99.7 35.6 0.9 11.5 621.4 14.7 0.0 2.9 1.6 59.0 0.0 10.5 29.5 14.4 98.4 18.1 37.5 3.6 14.2 4.7 0.8 101.3 1.1 16.9 29.9 0.3 31.8 6.0 10.8 0.0 10.6 102.3 40.7 1.6 1.7 33.1 10.8 11.0 5.4 1.9 0.0 4.2 0.0 4.5 7.6 2.3 106.1 1.2 1.2 312.9 140.7 19.7 149.3 0.7 0.0 7.7 46.7 3.8 0.7 7.8 0.4 11.4 3.3 0.1 88.3 737.7 RASEF "FLJ31614, RAB45" ENSG00000165105 "RAS and EF-hand domain containing" Q8IZ41 9 82979590-83063177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 41.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 101.7;Gastric mucus-secreting cells: 356.8;Prostatic glandular cells: 106.4;Respiratory ciliated cells: 100.6;Urothelial cells: 107.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 53.2;RT4: 38.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021431, HPA078596" Approved Uncertain Microtubules NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Microtubules "HPA021431: AB_1856087, HPA078596: " "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.26e-1)" "unprognostic (2.59e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-3)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (8.60e-2)" "unprognostic (1.66e-3)" "unprognostic (3.67e-1)" "unprognostic (1.41e-3)" "unprognostic (5.07e-2)" "unprognostic (6.05e-3)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" 1.1 1.6 16.2 2.8 15.4 3.6 17.6 21.2 21.9 2.9 18.0 15.2 6.3 2.7 10.2 7.1 6.3 12.6 1.1 13.9 9.2 5.3 2.4 8.2 1.5 10.0 6.3 1.5 23.1 5.3 3.9 3.4 9.8 15.2 15.2 5.1 15.3 3.8 1.9 3.8 8.6 1.1 1.0 1.5 41.0 4.0 9.8 3.4 25.9 0.0 3.5 13.8 2.3 24.7 14.0 15.5 1.8 1.5 0.3 0.5 5.6 1.0 0.2 1.6 3.9 8.7 16.9 2.3 13.7 0.4 11.0 16.3 0.3 0.4 1.9 1.4 17.3 1.9 11.9 2.2 0.2 1.7 1.6 0.3 6.7 7.6 0.2 2.1 0.1 2.4 2.5 16.8 0.2 27.2 2.3 1.8 10.5 53.2 6.1 2.5 4.8 6.0 18.0 38.5 5.6 8.3 2.8 26.8 1.1 6.7 22.9 2.0 2.6 2.6 14.6 2.1 1.7 11.3 10.1 1.4 5.8 1.0 3.0 6.5 2.0 1.9 3.7 1.4 3.5 3.9 3.5 2.9 1.1 5.3 3.8 3.3 9.8 3.6 1.6 3.8 2.9 0.7 16.2 15.4 21.2 21.9 13.9 9.2 10.0 6.3 9.8 1.0 9.8 24.7 0.7 76.9 101.7 0.3 1.1 0.8 5.4 7.9 4.0 1.1 61.3 21.1 0.6 42.9 59.7 9.2 4.2 5.5 0.5 61.8 7.9 35.4 0.6 39.7 7.9 4.5 3.6 0.8 1.0 37.4 10.3 5.7 356.8 88.2 22.1 0.4 0.7 1.7 0.8 0.0 0.6 85.7 48.8 0.0 0.4 2.1 0.3 4.2 1.8 4.7 1.6 0.1 0.0 0.0 0.2 46.2 40.0 0.0 1.5 106.4 10.4 8.3 100.6 1.3 0.0 0.7 2.8 0.5 4.8 28.2 0.9 7.5 3.1 1.2 35.7 107.7 RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 220.6;Inhibitory neurons: 407.6;Microglial cells: 89.0;Oligodendrocytes: 395.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cell line enhanced" "Detected in some" "BEWO: 37.8;CACO-2: 23.3;Hep G2: 31.8;HHSteC: 20.8;hTERT-RPE1: 15.3;SuSa: 16.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 24.5;cerebral cortex: 77.3;hippocampal formation: 46.6;olfactory bulb: 27.0" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" 11.2 0.9 10.5 3.4 9.4 1.0 7.3 1.2 14.9 3.4 16.1 2.9 1.8 2.4 0.8 1.3 2.2 5.2 5.4 11.6 4.8 4.8 0.5 3.3 3.5 3.4 2.2 17.6 1.0 2.3 4.1 10.2 2.5 3.6 1.4 22.9 1.5 1.5 2.7 1.1 2.4 2.6 5.1 2.2 1.8 2.0 13.8 1.5 4.7 6.8 2.8 3.4 2.4 10.0 0.0 2.1 0.5 0.3 0.0 0.0 37.8 0.7 9.3 0.4 0.4 23.3 0.0 0.4 11.9 0.0 0.2 0.6 0.0 0.0 1.2 0.6 4.0 0.2 0.3 31.8 20.8 0.0 0.0 1.0 0.1 8.8 0.1 15.3 0.2 0.5 0.0 0.1 0.0 0.3 0.3 0.2 4.5 0.0 0.1 0.2 4.5 0.1 1.4 0.0 0.4 0.5 0.1 0.0 0.3 16.2 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.4 0.0 0.0 0.0 1.9 0.0 5.2 0.0 2.6 1.5 0.0 0.0 4.2 3.0 0.0 0.0 0.0 0.0 0.7 1.0 10.5 9.4 1.2 14.9 11.6 4.8 3.4 2.2 2.5 5.1 13.8 10.0 45.3 0.0 1.1 10.1 0.6 1.7 0.3 0.1 0.0 15.9 0.2 0.3 5.2 0.0 0.6 9.2 58.4 1.1 2.2 0.2 0.0 0.4 10.2 1.3 0.3 23.7 0.0 0.0 220.6 0.0 26.9 2.5 0.5 1.1 0.0 0.2 5.3 0.1 1.1 1.7 407.6 0.5 0.0 0.3 0.8 3.0 0.9 0.5 1.8 89.0 0.2 3.7 6.2 8.5 395.6 0.7 1.2 9.1 0.9 0.3 1.0 2.1 0.0 42.1 0.0 1.5 0.9 6.7 1.6 0.3 0.6 0.8 7.5 4.1 1.3 0.5 RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "dendritic cells: 71.4;Excitatory neurons: 54.1;Muller glia cells: 86.9;Plasma cells: 43.0;T-cells: 84.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Group enriched" "Detected in many" 4 "HDLM-2: 54.5;JURKAT: 70.2;MOLT-4: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" 1.1 0.8 6.7 10.5 16.8 8.5 1.7 23.7 13.2 0.8 0.0 1.4 2.4 1.4 0.4 5.9 4.4 2.5 1.2 11.6 3.3 5.5 1.1 4.1 21.4 15.3 2.5 0.4 1.8 0.5 0.5 0.9 17.9 0.7 2.1 29.7 1.7 0.7 0.4 6.9 3.6 0.6 0.0 8.9 4.5 2.0 8.8 45.7 0.6 0.7 16.4 3.4 2.0 9.2 0.0 0.4 1.0 0.3 0.0 0.0 0.1 4.1 1.2 2.0 1.7 4.5 0.0 11.6 0.9 0.1 0.2 0.2 2.4 0.0 1.9 54.5 2.2 0.9 0.5 0.0 0.6 0.5 0.8 0.0 0.1 1.1 0.0 0.0 0.0 70.2 0.5 3.6 0.0 1.7 52.3 0.1 0.7 0.0 0.0 14.4 0.3 0.0 2.0 0.1 4.7 1.7 2.6 0.1 0.2 1.5 1.2 0.0 0.2 0.4 1.6 5.6 0.8 8.7 4.6 13.6 0.2 0.1 0.6 0.0 0.0 0.9 5.2 0.0 3.7 1.1 5.7 5.2 0.0 0.6 5.2 5.3 0.2 2.4 0.0 0.0 10.3 1.4 6.7 16.8 23.7 13.2 11.6 3.3 15.3 2.5 17.9 0.0 8.8 9.2 0.9 6.4 10.7 6.5 26.5 2.4 0.4 6.8 4.6 9.6 3.4 2.0 4.5 5.7 2.7 33.1 10.4 0.3 71.4 0.1 3.9 18.4 1.5 7.6 1.6 0.8 0.0 0.0 54.1 10.0 0.2 1.2 1.1 6.6 3.8 0.4 1.1 0.5 0.7 6.7 16.5 1.3 0.0 0.8 6.1 0.7 0.0 3.0 7.2 9.4 3.0 86.9 34.0 2.5 3.9 34.1 0.0 0.0 43.0 0.7 0.3 7.8 0.4 21.3 0.0 1.9 1.3 1.2 3.8 4.0 8.2 0.0 84.7 0.3 0.9 0.5 RASL12 RIS ENSG00000103710 "RAS like family 12" Q9NYN1 15 65053337-65076690 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 22.5;Peritubular cells: 57.9;Sertoli cells: 98.6;Smooth muscle cells: 55.7" "Cancer enhanced" "Detected in all" "glioma: 21.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.0;CACO-2: 14.5;EFO-21: 22.7;NTERA-2: 9.9;SuSa: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (6.13e-3)" "unprognostic (1.06e-1)" "unprognostic (2.47e-2)" "unprognostic (6.95e-2)" "unprognostic (1.39e-1)" "unprognostic (1.21e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-3)" "unprognostic (1.60e-1)" "unprognostic (4.45e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (1.76e-2)" "unprognostic (4.72e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.17e-4)" 27.9 3.9 32.9 5.1 36.8 0.0 15.7 30.8 24.4 49.8 8.5 35.6 3.6 61.6 27.9 19.2 54.7 13.2 53.4 26.0 38.4 6.9 1.1 38.4 3.3 39.4 57.4 16.5 2.4 1.8 7.0 17.0 38.0 52.5 6.7 3.3 8.0 76.4 37.1 12.1 9.4 33.0 38.8 9.6 7.7 15.6 66.1 0.9 8.4 20.6 1.7 40.2 33.5 32.6 0.1 0.1 0.2 0.0 0.6 5.0 0.2 0.0 0.5 0.0 0.0 14.5 0.1 0.0 22.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 9.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 17.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 36.8 30.8 24.4 26.0 38.4 39.4 57.4 38.0 38.8 66.1 32.6 7.4 0.0 0.0 22.5 0.0 1.5 3.9 0.0 0.0 0.3 2.0 5.6 16.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 4.7 0.3 12.6 3.6 0.0 0.0 0.1 0.0 0.1 15.2 0.5 0.5 0.0 12.3 1.4 0.1 0.3 0.0 0.1 0.0 2.0 0.0 1.3 3.9 13.1 0.2 0.0 2.8 0.0 17.9 0.0 0.0 0.0 0.1 0.0 57.9 0.0 0.4 0.5 0.0 0.0 0.8 98.6 0.9 55.7 0.7 1.1 0.4 0.1 0.3 0.2 0.4 0.2 0.1 RBBP5 "RBQ3, SWD1" ENSG00000117222 "RB binding protein 5, histone lysine methyltransferase complex subunit" Q15291 1 205086142-205122015 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049042, HPA058085" Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Nucleoli" "HPA049042: AB_2680610, HPA058085: AB_2683600" "unprognostic (8.72e-2)" "unprognostic (6.35e-2)" "unprognostic (2.14e-2)" "unprognostic (1.36e-2)" "unprognostic (1.60e-1)" "unprognostic (1.17e-1)" "unprognostic (4.61e-3)" "unprognostic (1.24e-1)" "unprognostic (3.07e-2)" "unprognostic (2.88e-1)" "unprognostic (2.75e-1)" "unprognostic (4.98e-2)" "unprognostic (6.90e-2)" "unprognostic (3.78e-3)" "unprognostic (4.95e-2)" "unprognostic (1.28e-1)" "unprognostic (4.88e-2)" 6.3 8.2 4.7 7.2 5.3 9.5 7.9 6.4 6.4 7.8 2.7 7.0 7.1 8.1 7.5 7.0 7.5 6.1 6.4 5.7 5.3 12.4 11.0 6.6 11.3 3.4 3.8 9.5 8.2 9.4 6.1 6.5 3.8 6.9 8.0 9.8 7.6 6.9 8.7 8.5 6.7 7.1 4.3 9.3 6.7 6.1 4.5 13.2 9.8 9.9 12.8 7.5 5.2 6.4 16.3 16.9 16.0 19.0 21.8 12.5 17.3 15.2 12.9 19.0 18.8 17.9 19.1 25.3 11.3 11.1 15.5 18.2 26.9 10.1 22.4 21.6 14.5 21.2 16.4 14.6 14.1 26.9 16.6 10.1 12.9 17.6 15.0 12.7 15.4 17.9 41.6 25.2 16.0 15.0 26.1 11.3 26.1 14.2 27.9 22.9 33.9 31.6 13.2 11.7 25.0 20.1 21.3 22.3 19.2 19.0 24.2 14.9 11.8 15.6 16.6 23.1 20.2 12.2 18.3 30.6 13.9 16.5 24.5 22.0 4.9 7.9 8.0 6.4 8.5 7.8 7.4 8.1 5.4 6.2 7.1 8.7 11.6 8.2 8.3 6.0 8.1 3.5 4.7 5.3 6.4 6.4 5.7 5.3 3.4 3.8 3.8 4.3 4.5 6.4 14.7 19.2 12.2 11.4 31.0 26.9 9.7 5.9 15.9 14.5 18.9 14.6 7.1 8.6 13.4 22.0 29.2 9.1 25.2 15.8 9.8 12.1 7.3 13.1 14.0 13.2 12.1 23.1 19.9 11.6 10.7 13.5 9.7 21.0 13.9 25.6 17.2 21.8 10.9 16.8 15.7 14.0 10.2 15.6 25.9 3.2 12.8 17.9 19.6 8.4 15.6 12.6 15.5 14.6 21.2 13.6 9.8 16.1 25.9 13.5 14.7 28.8 13.2 18.3 19.7 21.9 14.1 10.2 20.4 14.6 33.8 10.8 27.9 12.6 15.8 13.4 RBL1 "cp107, p107, PRB1" ENSG00000080839 "RB transcriptional corepressor like 1" P28749 20 36996349-37095997 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 23.3;Inhibitory neurons: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054962, HPA056525" Enhanced Enhanced Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA054962: AB_2682652, HPA056525: AB_2683165" "unprognostic (1.97e-1)" "unprognostic (2.47e-2)" "unprognostic (1.30e-2)" "unprognostic (3.70e-3)" "unprognostic (2.13e-1)" "unprognostic (1.51e-1)" "unprognostic (6.25e-5)" "unprognostic (6.91e-2)" "unprognostic (7.19e-3)" "unprognostic (1.20e-1)" "unprognostic (4.49e-3)" "unprognostic (3.23e-2)" "prognostic unfavorable (2.52e-6)" "unprognostic (3.15e-2)" "unprognostic (2.75e-1)" "unprognostic (1.47e-2)" "unprognostic (1.26e-1)" 2.0 1.6 1.2 4.8 2.6 14.5 2.8 8.3 1.8 2.3 0.7 2.8 2.4 2.8 1.3 2.9 1.9 2.0 1.8 1.0 1.9 1.6 1.4 2.2 7.3 2.0 1.9 4.4 2.4 2.6 1.1 3.4 2.2 2.0 3.5 4.0 1.5 1.4 6.9 3.1 2.5 2.8 1.4 3.4 2.7 3.1 2.0 8.8 2.7 7.9 6.7 2.0 2.2 3.4 24.8 15.8 19.4 13.1 4.9 6.4 12.4 28.2 12.6 23.9 24.6 16.8 13.5 27.5 7.9 11.8 14.0 23.8 17.5 18.2 39.7 9.7 9.4 27.2 18.1 14.3 3.0 35.3 18.2 3.0 2.5 31.6 11.1 4.0 13.6 17.9 20.1 25.8 13.7 10.5 33.1 11.7 5.7 12.5 15.3 21.3 57.7 20.9 5.5 12.2 4.6 11.5 30.8 17.6 8.2 6.2 11.3 25.3 9.1 42.0 15.9 38.9 24.8 8.6 16.4 27.7 30.2 24.4 21.1 0.9 0.7 1.4 2.7 0.8 2.3 3.0 3.0 2.5 1.3 2.1 3.2 2.7 0.3 2.2 1.2 3.0 4.5 0.9 1.2 2.6 8.3 1.8 1.0 1.9 2.0 1.9 2.2 1.4 2.0 3.4 3.5 6.4 11.0 10.4 8.7 2.4 1.5 1.7 4.0 5.9 2.5 1.7 2.9 1.5 6.1 0.0 2.1 5.9 6.5 1.8 0.0 1.8 1.5 2.2 4.3 3.3 1.2 23.3 14.7 1.1 5.1 4.6 2.6 2.9 8.8 9.0 2.2 1.4 4.5 3.3 22.8 1.9 0.0 3.0 3.2 0.6 2.1 6.8 1.8 6.5 4.7 3.1 7.2 19.6 18.5 0.9 3.6 3.0 14.1 0.8 1.0 0.7 0.9 12.2 6.6 8.5 4.1 17.5 8.7 5.3 1.3 3.8 11.7 6.4 3.5 0.9 RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 442.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 136.2" "Group enriched" "Detected in many" 12 "dendritic cells: 34.4;granulocytes: 136.2;monocytes: 45.5" "Cell line enhanced" "Detected in many" "BEWO: 134.0;CAPAN-2: 63.5;OE19: 56.7;SK-BR-3: 58.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA006347: AB_2181208" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.49e-3)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-2)" "unprognostic (7.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (9.42e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-16)" "unprognostic (1.62e-2)" "unprognostic (9.81e-2)" "unprognostic (1.72e-1)" "unprognostic (5.77e-2)" 9.3 49.7 2.2 20.3 1.9 9.6 24.7 1.8 3.0 15.3 44.9 61.0 68.4 3.5 23.1 42.2 17.7 17.9 1.3 2.8 2.3 67.6 34.5 21.0 8.2 6.0 3.2 2.2 25.9 27.8 3.2 20.1 4.9 33.2 50.5 0.4 59.4 13.4 0.5 9.0 64.1 4.7 4.1 14.7 64.6 6.7 5.7 4.4 49.5 1.1 11.4 22.6 15.5 6.8 31.9 47.8 0.0 1.8 0.2 0.0 134.0 0.8 1.6 0.1 0.6 28.3 63.5 0.2 23.0 1.2 3.8 14.2 0.9 11.8 0.3 0.2 7.6 0.0 3.1 7.9 0.6 0.3 0.3 0.8 6.0 0.1 0.1 1.8 0.0 0.0 1.8 7.0 0.1 18.1 0.2 1.1 13.5 56.7 2.4 0.2 0.0 34.7 46.8 41.6 1.6 0.3 17.3 58.4 0.3 14.8 23.9 9.0 0.0 0.5 1.9 0.3 1.0 23.5 37.7 4.1 5.0 3.9 0.2 0.5 45.5 0.5 0.2 33.1 0.3 5.9 0.2 0.1 34.4 5.4 0.4 0.1 136.2 0.5 26.2 14.1 0.2 16.9 2.2 1.9 1.8 3.0 2.8 2.3 6.0 3.2 4.9 4.1 5.7 6.8 1.1 80.1 116.6 0.7 21.2 58.9 75.2 42.9 95.0 0.1 145.7 63.5 1.9 75.8 92.2 112.2 0.0 99.6 16.3 442.8 64.6 90.6 1.3 132.6 9.5 6.0 121.9 2.5 2.5 115.4 84.3 7.7 174.8 143.7 7.0 8.7 23.6 140.4 92.6 1.7 1.9 234.2 59.0 138.8 92.8 2.6 2.5 119.9 37.4 82.4 80.6 0.3 1.0 2.5 0.8 108.0 228.1 1.2 40.1 164.7 218.1 143.6 118.3 0.1 0.0 1.4 5.1 2.6 10.4 178.1 75.4 262.6 4.8 16.9 203.8 295.4 RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 11920.3" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 12711.6" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 1117.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" NA NA 46100000000 210000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" 730.7 32.4 30.2 6.2 34.4 1.1 394.2 12.4 48.1 5.8 12.4 11.2 4.8 2.3 0.9 1.1 2.1 7.5 16.7 32.2 113.0 142.8 11920.3 24.5 0.6 21.5 19.3 4.1 82.4 0.1 519.9 12.4 21.3 8.6 6.7 3.0 13.7 4.6 6.2 16.4 19.2 0.8 14.9 5.5 11.9 4.7 46.2 1.5 7.9 5.3 0.1 19.0 8.8 18.0 0.0 14.7 0.0 0.0 2.9 0.0 0.1 0.3 0.1 2.5 0.4 264.9 0.5 1.5 2.7 0.3 0.2 0.8 0.0 0.0 0.3 0.2 0.2 2.2 1.1 1117.2 0.2 9.2 0.2 18.7 0.5 0.7 0.0 0.0 0.0 0.0 1.4 0.2 1.2 0.0 0.1 7.3 1.3 2.4 121.7 0.4 7.0 0.0 0.0 0.6 0.9 0.2 9.6 0.0 0.0 0.6 0.5 0.8 0.4 0.0 7.8 0.2 0.3 0.9 0.3 3.7 0.0 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 34.4 12.4 48.1 32.2 113.0 21.5 19.3 21.3 14.9 46.2 18.0 9.1 0.0 4.2 0.3 17.2 0.8 0.5 0.0 0.0 0.0 2.1 6.7 0.7 999.4 0.6 23.9 6.2 0.3 0.2 21.9 97.8 7.8 2.8 1.6 3.1 10.8 62.5 152.4 5.8 0.2 22.6 10.5 0.0 22.1 0.0 0.0 158.1 12711.6 17.8 0.0 7.2 40.7 0.0 210.4 3.0 2.4 3.1 7.8 1.8 1.0 0.0 0.8 0.0 1.0 1.1 29.2 28.0 5.7 0.3 2.1 0.8 785.3 0.7 0.5 0.0 7.3 3.8 3.1 13.9 0.0 0.9 1.4 12.3 0.0 1.7 1.4 RBP5 CRBPIII ENSG00000139194 "Retinol binding protein 5" P82980 12 7115736-7128889 "Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 443.5;liver: 324.2" "Cell type enriched" "Detected in many" 8 "Proximal tubular cells: 3197.2" "Group enriched" "Detected in all" 8 "liver cancer: 70.1;renal cancer: 126.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.0;Hep G2: 13.4;K-562: 26.3" HPA038723 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Vesicles "HPA038723: AB_2676175" "unprognostic (5.70e-3)" "unprognostic (7.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.53e-2)" "unprognostic (1.87e-2)" "unprognostic (1.39e-3)" "unprognostic (2.49e-2)" "prognostic favorable (8.37e-4)" "unprognostic (1.04e-1)" "unprognostic (2.65e-1)" "unprognostic (1.13e-2)" "unprognostic (1.13e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-2)" "unprognostic (3.33e-2)" "unprognostic (4.22e-1)" "prognostic favorable (3.68e-4)" 6.4 11.7 0.0 15.0 0.1 1.6 5.1 0.3 0.3 11.2 0.2 8.5 4.6 8.6 3.2 3.8 8.1 5.9 1.4 0.0 0.0 443.5 324.2 3.8 31.2 0.5 0.3 4.9 5.2 1.3 6.2 0.3 0.3 10.0 4.9 0.8 3.7 5.0 0.7 2.4 20.6 5.4 0.0 97.1 5.2 2.2 0.2 14.2 7.9 0.0 21.4 7.4 4.6 0.0 0.9 1.3 0.0 0.3 0.0 0.0 0.2 1.1 0.0 0.0 0.2 1.1 1.2 1.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 1.6 0.0 6.0 3.9 13.4 0.0 0.2 0.9 0.2 0.0 0.0 0.0 2.4 0.0 0.6 26.3 0.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.1 0.1 1.2 0.0 0.2 1.4 0.9 0.0 0.6 0.5 0.7 0.7 0.6 0.5 2.8 0.4 0.3 0.1 0.0 0.3 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.5 0.3 0.3 0.0 0.2 0.0 4.9 0.0 0.6 0.7 15.2 1.5 0.5 0.1 0.0 1.2 1.3 1.3 0.1 5.7 0.1 80.9 0.0 0.1 0.3 0.1 352.1 0.2 4.1 0.3 1.7 28.8 0.0 0.0 2.1 0.4 0.0 8.2 0.0 0.5 0.0 0.2 8.9 361.1 0.1 5.0 1.1 0.0 0.0 8.1 2.6 6.7 2.5 16.6 0.0 1.9 0.0 1.4 0.0 0.5 0.1 0.2 0.0 0.4 0.1 0.5 0.0 3197.2 0.9 1.7 0.0 0.1 4.3 0.7 0.4 0.2 2.3 0.0 7.3 2.4 0.1 0.3 RBPMS HERMES ENSG00000157110 "RNA binding protein, mRNA processing factor" Q93062 8 30384511-30572256 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 324.1;RPTEC TERT1: 232.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056999 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA056999: AB_2683306" "unprognostic (1.65e-1)" "unprognostic (7.81e-2)" "unprognostic (1.53e-1)" "unprognostic (2.23e-3)" "unprognostic (8.66e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-2)" "unprognostic (3.47e-3)" "unprognostic (4.63e-2)" "unprognostic (2.32e-1)" "unprognostic (4.67e-2)" "unprognostic (2.88e-2)" "unprognostic (1.76e-2)" "unprognostic (4.76e-2)" "unprognostic (2.52e-1)" "unprognostic (4.91e-2)" "unprognostic (2.16e-3)" 238.3 96.7 22.3 43.8 28.0 1.4 194.8 20.2 24.1 196.9 26.7 350.6 25.2 200.7 90.0 99.9 200.5 95.4 174.7 17.3 25.2 218.7 108.9 119.6 23.3 23.1 27.6 190.0 68.8 68.6 33.0 105.0 28.7 182.6 46.6 10.4 92.1 193.7 31.2 56.6 107.7 171.9 18.7 56.7 159.8 45.4 33.2 23.5 140.7 31.6 20.0 323.4 134.0 18.9 0.7 54.5 58.5 0.4 324.1 96.4 145.8 74.8 101.8 90.2 74.6 76.2 31.2 0.5 39.3 96.7 82.5 29.9 68.0 54.4 107.9 0.1 14.6 1.8 24.7 80.5 139.4 0.5 12.0 112.8 13.8 86.7 11.5 100.8 52.8 2.5 0.5 0.4 44.6 32.6 0.3 1.2 150.9 62.3 34.6 3.5 16.2 4.7 232.2 88.9 1.1 11.6 7.7 55.2 37.7 192.3 11.7 0.0 48.8 44.3 4.2 77.3 12.8 0.1 0.2 0.4 72.8 0.2 20.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 22.3 28.0 20.2 24.1 17.3 25.2 23.1 27.6 28.7 18.7 33.2 18.9 104.0 54.5 98.9 36.6 4.5 9.3 61.8 22.7 14.2 6.7 45.8 64.3 114.4 75.8 48.5 141.6 2.1 108.7 4.1 1.8 113.5 100.0 104.7 31.2 86.3 69.7 1.8 5.0 6.4 94.8 184.8 66.7 18.8 48.2 10.1 18.0 44.3 55.2 39.9 0.0 5.2 0.1 20.3 1.9 10.2 31.5 171.2 4.3 14.2 71.2 2.1 1.0 1.0 2.0 1.6 67.0 0.0 180.2 0.5 101.5 2.0 242.2 30.9 5.7 111.7 6.6 149.9 35.3 22.0 27.8 8.0 41.2 4.4 28.1 1.0 151.7 RCAN2 "DSCR1L1, ZAKI-4" ENSG00000172348 "Regulator of calcineurin 2" Q14206 6 46220736-46491972 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 199.5;tongue: 180.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 255.4;Excitatory neurons: 261.4;Inhibitory neurons: 254.4;Muller glia cells: 183.1;Oligodendrocytes: 294.6;Smooth muscle cells: 138.4" "Cancer enhanced" "Detected in all" "renal cancer: 25.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "gdT-cell: 1.8;memory CD4 T-cell: 1.1;memory CD8 T-cell: 2.2;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 23 "T-cells: 2.2" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 63.3;HDLM-2: 129.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053880 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Nucleoplasm "HPA053880: AB_2682290" "unprognostic (2.82e-1)" "unprognostic (7.76e-2)" "unprognostic (4.13e-2)" "unprognostic (1.14e-1)" "unprognostic (5.55e-3)" "unprognostic (4.52e-2)" "unprognostic (1.29e-3)" "unprognostic (1.86e-3)" "unprognostic (2.26e-1)" "unprognostic (4.33e-1)" "prognostic favorable (2.48e-4)" "unprognostic (1.37e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (2.11e-2)" 38.1 12.6 35.7 7.7 41.2 0.0 17.1 31.7 106.3 20.3 0.0 20.1 9.8 17.5 51.5 25.9 17.0 35.1 199.5 34.0 65.0 32.4 4.9 16.3 4.1 69.6 76.0 24.0 11.1 85.5 17.5 0.6 68.8 25.3 22.6 61.6 9.6 27.0 73.3 17.2 19.1 14.0 20.6 7.1 36.5 5.7 65.5 4.7 20.1 180.1 7.0 44.0 21.4 62.3 0.0 0.0 1.6 0.0 0.7 0.2 0.1 1.1 15.1 1.1 0.1 0.0 0.0 0.0 0.8 63.3 0.0 0.1 0.0 0.0 0.3 129.7 0.8 0.0 0.0 0.0 1.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.1 5.1 0.0 0.0 0.2 2.7 0.4 0.4 0.4 13.6 0.1 0.2 0.3 4.9 0.0 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.1 1.8 0.1 0.2 6.8 0.1 0.0 0.2 0.0 0.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.1 2.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 35.7 41.2 31.7 106.3 34.0 65.0 69.6 76.0 68.8 20.6 65.5 62.3 7.6 6.4 5.8 13.7 0.6 6.2 4.6 0.0 0.0 24.8 1.8 1.4 255.4 8.6 0.0 3.7 4.2 0.1 0.8 1.0 70.5 5.5 40.2 0.8 0.4 17.1 25.1 0.0 261.4 2.5 0.0 22.2 1.5 0.8 0.0 0.3 0.4 1.2 0.1 30.3 254.4 1.5 34.6 0.3 8.0 14.2 29.2 0.9 32.0 46.9 0.0 183.1 0.0 76.9 294.6 2.9 0.3 50.4 0.4 3.3 0.0 1.9 0.0 9.7 98.6 16.4 138.4 1.5 1.4 0.5 7.4 0.0 4.0 0.8 0.3 1.4 RCC2 TD-60 ENSG00000179051 "Regulator of chromosome condensation 2" Q9P258 1 17406760-17439677 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072281 Approved NA NA 110000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA072281: AB_2686505" "unprognostic (2.50e-2)" "prognostic favorable (3.31e-4)" "unprognostic (9.91e-2)" "unprognostic (1.72e-1)" "unprognostic (2.74e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (3.42e-8)" "unprognostic (3.05e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (1.73e-1)" "unprognostic (1.31e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (4.03e-8)" "unprognostic (6.81e-3)" "unprognostic (2.09e-1)" "unprognostic (9.44e-2)" "unprognostic (4.41e-2)" 19.4 18.4 12.3 18.9 12.2 33.3 22.2 12.8 13.2 24.8 11.0 24.0 11.4 18.7 9.9 65.2 16.3 11.8 13.4 12.1 12.5 22.8 15.9 24.2 27.7 14.2 13.6 22.1 21.3 9.4 11.4 16.1 13.1 22.3 17.6 3.1 36.0 7.8 8.4 56.3 27.6 10.2 13.9 39.2 18.3 20.6 15.8 34.2 19.0 4.1 35.2 19.7 31.3 15.3 62.2 34.3 68.4 57.9 25.3 25.4 56.6 24.3 20.9 49.2 40.4 37.0 83.4 133.8 80.4 25.3 14.5 67.4 121.0 70.0 34.1 64.3 61.1 117.6 50.5 36.0 31.8 142.7 79.7 40.5 51.8 55.1 48.7 30.7 53.3 88.7 82.4 188.4 22.0 62.9 117.4 115.9 94.7 76.0 26.0 155.7 68.6 86.5 37.3 29.0 102.9 72.6 61.4 59.5 93.6 56.7 53.2 91.3 41.9 44.8 56.0 18.1 51.1 81.7 72.9 165.8 19.3 158.6 90.9 0.9 1.9 0.7 1.4 2.6 1.2 1.6 1.1 1.4 3.1 1.7 0.8 1.4 0.1 1.7 2.1 2.5 1.0 1.1 12.3 12.2 12.8 13.2 12.1 12.5 14.2 13.6 13.1 13.9 15.8 15.3 22.6 25.6 15.3 16.6 26.4 46.5 14.7 25.3 27.9 6.6 36.5 34.3 0.9 18.6 26.6 22.0 10.4 25.0 32.2 27.5 3.9 24.4 6.8 28.0 38.3 24.9 24.1 28.8 11.0 22.7 48.9 17.4 14.8 37.5 17.7 55.9 17.5 7.3 32.6 6.7 4.9 25.9 24.4 31.4 70.0 21.0 9.3 43.0 16.0 20.6 27.9 15.3 22.6 20.6 15.3 28.8 20.6 6.0 25.9 32.2 7.5 7.0 17.9 5.4 0.0 20.7 16.7 17.6 21.2 42.9 64.5 16.3 19.7 25.6 36.4 19.4 RDH11 "ARSDR1, MDT1, SDR7C1" ENSG00000072042 "Retinol dehydrogenase 11" Q8TC12 14 67676800-67695793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cataract, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 582.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 241.8;Muller glia cells: 299.7;Prostatic glandular cells: 285.7" "Cancer enriched" "Detected in all" 13 "prostate cancer: 286.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046011 Enhanced "Intracellular and membrane" NA NA 340000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "CAB046011: AB_11129613" "unprognostic (1.38e-1)" "unprognostic (6.86e-3)" "unprognostic (1.77e-1)" "prognostic favorable (2.62e-4)" "unprognostic (6.06e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (9.29e-2)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.58e-2)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "prognostic favorable (1.30e-7)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (4.74e-2)" 23.6 59.5 39.3 24.5 43.2 13.9 28.7 50.2 54.4 32.6 35.9 29.2 34.1 33.2 86.0 34.6 23.5 42.7 17.6 40.4 47.2 106.0 153.1 34.9 20.4 49.2 47.7 28.9 42.6 79.8 23.4 21.9 49.3 582.0 31.4 73.9 44.2 34.4 8.3 31.4 23.9 43.6 49.8 22.2 31.9 28.4 46.1 30.7 61.7 13.5 26.2 34.3 30.3 58.4 183.7 81.9 71.3 82.0 111.5 100.4 59.3 68.0 134.2 83.7 150.9 68.6 216.7 31.7 51.2 64.6 104.8 142.5 104.0 150.8 113.7 63.0 42.6 65.1 40.7 69.0 106.9 24.3 46.0 94.4 98.0 109.3 92.0 63.9 97.4 87.0 52.1 101.1 77.2 97.5 72.2 38.8 40.4 49.7 92.8 53.6 87.4 45.8 194.1 93.0 73.8 62.0 71.2 89.7 99.1 58.2 100.7 38.3 74.2 89.5 101.1 38.9 49.5 47.5 40.0 40.7 115.8 66.0 74.3 282.4 71.1 104.0 62.3 57.7 68.2 39.0 67.7 61.5 51.3 45.5 67.3 64.8 11.0 56.3 65.4 59.1 65.1 115.8 39.3 43.2 50.2 54.4 40.4 47.2 49.2 47.7 49.3 49.8 46.1 58.4 27.0 25.6 66.0 38.2 29.2 11.5 40.0 77.9 16.5 53.5 45.4 24.5 20.4 68.6 59.9 47.8 50.1 24.9 32.4 26.8 7.9 92.5 2.5 21.9 50.9 39.3 43.3 29.2 33.3 84.0 38.1 37.5 19.9 38.2 29.2 46.3 47.8 241.8 35.8 79.1 37.6 28.9 89.5 42.4 15.4 6.1 43.2 35.9 35.6 17.8 39.8 299.7 37.0 70.4 43.4 61.2 36.7 56.1 27.3 285.7 17.5 56.0 23.9 97.0 46.0 29.7 38.7 25.8 24.0 20.2 19.2 63.5 29.8 66.7 25.3 46.1 RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 222.7;skin 1: 63.8" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 146.0;Rod photoreceptor cells: 453.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (4.25e-3)" "unprognostic (4.50e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (2.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.69e-2)" "unprognostic (2.72e-3)" "unprognostic (7.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.42e-2)" "unprognostic (6.47e-2)" "unprognostic (7.83e-2)" "unprognostic (3.58e-1)" "unprognostic (3.92e-1)" 0.1 4.1 1.3 0.1 1.0 0.1 2.2 1.0 1.4 11.0 0.4 0.0 0.3 0.0 8.7 22.1 0.5 17.6 0.0 0.9 1.2 13.6 3.8 0.1 0.0 1.2 2.3 0.0 3.2 0.0 0.9 0.1 1.2 0.5 0.0 222.7 1.7 0.1 0.1 63.8 0.1 0.0 0.6 0.0 12.4 0.1 4.6 0.4 1.2 0.0 1.6 0.0 23.6 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.0 1.0 1.4 0.9 1.2 1.2 2.3 1.2 0.6 4.6 1.1 0.0 0.0 0.0 0.7 0.0 4.7 0.3 0.0 0.6 39.8 0.1 0.1 0.0 20.0 0.3 1.8 146.0 0.0 0.0 0.1 0.0 0.7 0.2 1.8 1.1 2.2 0.0 0.0 1.2 1.7 0.0 0.4 14.3 1.7 0.0 0.0 0.0 5.7 0.2 20.2 0.9 0.0 0.0 0.6 0.9 0.0 0.3 0.2 1.8 1.0 0.0 53.0 0.0 1.5 0.2 1.5 2.6 0.0 0.0 0.3 0.1 12.5 0.2 453.2 0.0 0.0 0.2 0.0 0.1 4.7 38.6 0.0 0.1 0.1 0.1 0.3 REEP1 "C2orf23, FLJ13110, SPG31, Yip2a" ENSG00000068615 "Receptor accessory protein 1" Q9H902 2 86213993-86338083 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 95.5;Oligodendrocyte precursor cells: 39.2" "Cancer enhanced" "Detected in many" "glioma: 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 68.1;HAP1: 15.0;RPMI-8226: 16.0;SCLC-21H: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058061 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA058061: AB_2683591" "unprognostic (1.94e-2)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.29e-2)" "unprognostic (5.10e-2)" "unprognostic (6.63e-2)" "unprognostic (9.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (6.15e-2)" "unprognostic (2.35e-1)" "unprognostic (2.56e-2)" "unprognostic (6.77e-2)" "unprognostic (2.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.07e-3)" 4.7 6.2 17.0 1.8 15.8 0.0 4.9 4.1 30.4 3.9 11.5 42.4 4.4 18.9 3.7 6.2 13.6 3.8 16.6 15.4 44.0 2.0 1.1 3.6 0.5 24.6 38.1 1.9 9.9 7.9 13.9 2.2 50.0 7.3 5.0 12.9 1.6 12.9 19.8 2.0 9.3 20.7 4.4 2.0 8.8 44.5 18.7 0.3 2.0 14.3 0.6 21.7 5.8 14.3 0.0 0.0 2.2 2.9 0.1 0.0 68.1 0.0 0.0 4.5 0.5 2.5 0.0 0.0 3.2 0.0 3.4 4.9 15.0 0.1 3.9 0.0 8.1 0.0 5.0 0.4 0.0 0.3 0.4 0.7 0.1 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.1 2.7 0.1 0.0 2.6 0.1 0.0 0.1 6.5 16.0 0.3 0.3 32.0 3.1 3.5 1.6 0.2 1.3 5.1 0.9 0.0 0.0 2.3 1.3 6.3 7.2 5.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 15.8 4.1 30.4 15.4 44.0 24.6 38.1 50.0 4.4 18.7 14.3 1.7 9.6 0.5 14.7 0.2 2.0 0.3 0.3 0.0 10.0 3.6 1.1 23.0 2.8 2.8 0.0 2.1 2.4 0.0 0.4 1.9 3.5 18.0 17.1 0.3 5.7 4.8 0.0 86.2 6.2 26.6 2.4 0.0 0.7 0.0 0.8 12.5 0.2 0.9 3.3 95.5 0.2 8.2 0.8 1.6 14.4 2.5 0.4 1.8 6.5 0.6 13.4 0.0 39.2 6.0 6.5 0.0 3.4 0.0 1.6 0.0 5.1 16.6 15.8 19.7 4.2 13.5 4.0 2.7 0.5 1.1 6.6 0.2 0.0 0.5 0.4 REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 217.5;liver: 398.0;testis: 283.9" "Cell type enhanced" "Detected in many" "Early spermatids: 559.1;Late spermatids: 3135.0;Proximal enterocytes: 898.7" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 57.9;Hep G2: 56.2;K-562: 155.7;T-47d: 121.4" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" 8.4 86.5 11.1 1.3 12.4 1.2 17.5 10.1 18.0 5.6 7.7 3.0 217.5 3.5 14.6 14.3 4.6 7.0 3.9 12.7 8.8 22.1 398.0 1.6 1.3 9.7 10.1 7.7 28.5 2.0 9.8 1.6 9.9 20.1 1.7 94.0 17.9 6.8 2.0 9.3 199.6 0.9 8.4 1.7 4.2 283.9 12.1 0.7 6.0 0.7 1.0 9.2 7.0 10.9 7.3 9.2 2.6 34.3 5.6 2.0 39.5 1.8 0.7 1.9 1.9 57.9 22.5 3.9 12.2 1.1 2.3 7.3 9.8 0.6 1.0 1.9 4.1 21.3 1.3 56.2 4.2 1.6 6.6 4.7 4.1 0.4 1.4 3.2 1.1 4.9 155.7 5.0 0.3 29.6 1.8 4.7 12.8 21.1 19.5 4.9 1.1 10.0 10.9 2.7 0.7 17.2 9.8 14.2 6.3 1.9 121.4 5.7 3.4 2.8 5.4 8.7 1.2 16.4 5.3 0.8 11.2 9.4 8.2 0.0 1.1 0.0 5.5 1.2 2.8 0.1 1.4 1.2 1.9 0.6 2.0 2.2 0.0 4.9 4.3 3.3 1.6 1.6 11.1 12.4 10.1 18.0 12.7 8.8 9.7 10.1 9.9 8.4 12.1 10.9 1.5 3.2 3.2 2.6 2.7 6.8 7.9 6.8 10.8 30.4 47.4 20.3 1.8 91.5 10.5 5.5 33.3 69.4 2.5 7.8 7.9 34.5 559.1 4.5 7.1 4.2 6.0 10.1 1.5 69.2 12.8 4.7 2.6 3.0 10.2 132.9 5.0 267.4 9.6 23.5 1.2 51.9 4.1 6.3 4.3 3135.0 34.2 4.1 30.2 0.0 1.7 44.2 2.1 0.0 1.5 25.0 53.6 16.6 1.9 13.1 898.7 52.0 8.3 292.8 19.7 0.8 3.3 29.9 36.5 17.5 6.7 36.0 4.3 50.1 70.7 14.7 RELCH "FLJ33841, HsT3308, HsT885, KIAA1468" ENSG00000134444 "RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing" Q9P260 18 62187255-62310249 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Cardiomyocytes: 9.4;Cytotrophoblasts: 6.5;dendritic cells: 8.2;Extravillous trophoblasts: 4.4;Hofbauer cells: 7.2;Plasma cells: 5.2;Syncytiotrophoblasts: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039708, HPA040038" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Centriolar satellite, Cytosol" "HPA039708: AB_10794753, HPA040038: AB_10793860" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (4.03e-2)" "unprognostic (1.98e-3)" "unprognostic (2.44e-2)" "unprognostic (6.30e-2)" "unprognostic (3.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.36e-1)" "unprognostic (4.84e-3)" "unprognostic (2.47e-2)" "unprognostic (6.86e-2)" "unprognostic (3.54e-1)" "unprognostic (1.71e-2)" 8.3 8.8 8.7 9.6 10.8 14.2 11.9 11.1 10.0 11.8 7.2 11.5 9.5 8.5 11.8 25.4 7.7 7.9 7.5 9.7 9.3 9.6 7.9 8.0 11.8 7.9 7.6 8.2 8.3 10.3 11.0 8.1 8.2 12.1 14.4 16.3 12.5 8.8 6.8 20.6 10.8 6.2 7.6 11.2 12.7 5.3 8.8 10.8 9.5 5.9 13.2 10.0 16.2 9.4 9.7 8.7 10.4 10.0 10.8 12.7 11.1 17.0 14.1 15.0 16.5 4.5 8.8 6.6 8.6 15.1 9.8 19.7 14.9 10.2 18.3 6.0 9.3 5.6 9.7 10.4 9.6 10.8 7.4 9.4 12.3 12.8 7.8 12.3 10.3 6.2 4.2 6.5 15.9 5.7 6.7 9.3 6.0 6.5 7.3 8.2 13.0 7.9 17.1 19.1 14.7 7.8 10.2 14.9 8.9 13.4 7.7 11.6 12.9 15.9 5.0 6.9 8.6 19.0 3.7 6.4 11.2 11.4 13.0 1.4 1.0 1.2 1.1 0.8 0.8 0.8 1.0 1.0 1.0 0.9 1.1 1.3 1.7 1.1 0.7 0.7 1.3 0.6 8.7 10.8 11.1 10.0 9.7 9.3 7.9 7.6 8.2 7.6 8.8 9.4 7.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 6.5 8.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 4.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 6.6 1.1 0.0 0.0 0.0 REPS1 ENSG00000135597 "RALBP1 associated Eps domain containing 1" Q96D71 6 138903493-138988261 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 207.3;Excitatory neurons: 114.3;Inhibitory neurons: 138.1;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029961, HPA029962" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane, Cytosol" "HPA029961: AB_10603233, HPA029962: AB_2673269" "unprognostic (1.72e-3)" "unprognostic (9.61e-2)" "unprognostic (5.82e-3)" "unprognostic (2.77e-2)" "unprognostic (6.30e-3)" "unprognostic (1.90e-1)" "prognostic unfavorable (9.47e-4)" "unprognostic (3.79e-1)" "unprognostic (2.49e-1)" "unprognostic (9.71e-3)" "unprognostic (4.29e-3)" "unprognostic (4.42e-2)" "unprognostic (2.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.27e-1)" "unprognostic (3.83e-2)" "unprognostic (2.69e-2)" 13.5 11.9 24.7 14.9 25.4 23.2 23.6 27.7 36.8 19.2 14.8 17.4 15.4 21.9 40.2 28.0 18.4 14.0 23.9 27.4 24.0 17.4 31.3 15.2 19.4 25.2 23.9 21.1 18.8 41.0 31.7 17.2 21.3 15.9 17.3 38.8 26.1 16.2 17.5 30.0 16.4 19.5 21.5 22.1 18.1 35.6 25.9 36.0 17.8 12.6 22.2 19.5 20.1 25.3 29.3 22.6 42.3 53.1 23.4 41.6 46.2 27.8 30.7 31.9 38.2 54.1 24.8 35.2 22.9 38.9 38.0 33.6 48.7 42.0 42.1 37.6 41.9 29.6 12.9 32.9 35.3 94.6 45.9 34.1 33.7 58.6 70.3 30.2 33.5 51.2 40.2 35.1 41.4 49.4 53.9 51.3 40.4 37.4 21.3 62.4 26.0 20.0 26.5 43.6 37.7 37.2 25.7 38.7 38.0 62.0 18.6 64.4 32.9 17.8 29.6 48.5 38.8 34.4 33.7 49.2 21.1 38.3 26.4 5.9 1.3 1.9 2.2 4.0 3.8 3.0 2.9 3.2 1.9 1.6 2.9 3.6 0.7 2.9 4.5 3.5 3.3 1.2 24.7 25.4 27.7 36.8 27.4 24.0 25.2 23.9 21.3 21.5 25.9 25.3 11.8 19.2 7.4 207.3 18.0 13.4 11.7 7.9 22.2 12.6 13.7 9.5 28.4 10.0 12.2 5.5 16.7 25.6 18.9 11.9 7.9 7.8 13.7 17.5 9.7 10.3 6.0 5.0 114.3 7.1 28.3 11.5 16.3 23.3 15.9 14.4 15.7 43.8 13.3 13.5 138.1 12.8 6.1 24.0 10.3 7.7 7.2 17.2 5.4 47.8 10.5 36.8 15.5 99.5 71.2 8.9 14.7 8.6 23.9 11.2 13.5 8.6 16.5 14.4 19.7 16.8 10.9 41.7 33.8 26.4 14.9 28.6 18.7 7.6 15.2 18.1 RFC2 "A1, RFC40" ENSG00000049541 "Replication factor C subunit 2" P35250 7 74231499-74254458 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 68.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029493 Approved Supported "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "HPA029493: AB_10603991" "unprognostic (1.25e-1)" "prognostic favorable (9.91e-4)" "unprognostic (1.44e-1)" "unprognostic (7.66e-3)" "unprognostic (1.17e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (2.08e-2)" "unprognostic (5.74e-2)" "unprognostic (2.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.09e-7)" "unprognostic (2.22e-1)" "unprognostic (6.65e-2)" "unprognostic (3.61e-2)" "unprognostic (2.59e-1)" 12.2 9.5 10.6 13.4 10.9 27.4 15.5 11.4 11.5 12.6 11.1 13.4 9.0 9.6 8.4 18.6 10.1 8.6 10.1 10.5 10.9 14.7 21.2 11.3 23.5 11.7 11.3 11.3 13.3 11.8 7.9 18.4 11.4 11.5 15.0 8.8 12.2 7.6 18.8 20.3 11.2 12.6 11.5 14.2 13.6 10.0 10.7 20.2 9.2 12.2 30.8 11.5 12.6 11.8 74.3 55.6 65.2 64.6 13.1 15.2 29.4 42.5 46.7 85.2 101.4 62.6 67.3 69.2 11.5 30.7 78.7 49.7 53.3 69.2 87.5 49.6 91.5 42.9 76.4 46.7 10.1 64.6 25.3 15.4 15.9 79.8 55.0 18.5 46.0 63.9 89.4 41.9 66.4 87.2 65.1 124.7 74.1 116.3 47.4 95.0 72.0 85.8 45.7 58.1 52.4 65.5 50.7 94.8 34.7 79.2 68.7 58.0 17.4 83.4 54.9 64.6 96.3 25.1 35.1 120.6 42.4 98.4 89.3 33.4 36.7 27.3 18.0 42.3 18.1 31.6 15.5 16.5 31.9 36.8 19.5 14.3 46.4 42.9 40.1 17.1 23.9 29.1 10.6 10.9 11.4 11.5 10.5 10.9 11.7 11.3 11.4 11.5 10.7 11.8 15.4 12.8 11.1 2.6 19.0 23.8 24.3 24.3 19.9 13.2 12.6 17.4 6.1 5.7 16.5 5.5 2.1 68.6 17.5 12.4 5.9 21.0 2.8 8.1 13.3 13.5 4.8 38.3 3.0 19.0 65.0 17.4 10.7 11.5 23.4 25.1 13.6 14.0 37.7 3.3 2.6 13.1 20.3 14.4 28.2 2.5 8.7 18.2 21.4 1.9 26.3 16.1 23.7 1.5 2.2 13.8 6.9 10.9 17.5 11.0 13.2 13.8 8.8 9.5 6.6 14.6 17.5 33.8 44.6 20.1 17.0 46.1 16.9 12.9 19.1 15.3 RFC4 "A1, RFC37" ENSG00000163918 "Replication factor C subunit 4" P35249 3 186789880-186807058 "Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 55.7;Spermatocytes: 86.7;Spermatogonia: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004557, HPA049123, HPA058507" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004557: AB_2178593, HPA049123: AB_2680642, HPA058507: AB_2683736" "unprognostic (2.45e-1)" "prognostic favorable (7.41e-5)" "unprognostic (2.84e-1)" "unprognostic (1.81e-3)" "unprognostic (1.03e-1)" "unprognostic (6.69e-3)" "prognostic unfavorable (6.75e-7)" "unprognostic (5.29e-3)" "unprognostic (1.15e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (7.38e-4)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (1.80e-2)" "unprognostic (4.98e-1)" "unprognostic (6.15e-2)" "unprognostic (2.16e-1)" 7.0 6.0 7.3 19.3 7.6 41.5 13.8 8.9 11.9 8.8 7.4 15.4 10.9 14.1 6.6 11.8 10.8 7.7 9.1 7.5 7.5 7.3 10.7 7.2 31.5 7.3 7.4 15.0 11.0 8.0 5.7 14.5 7.6 7.7 20.4 11.2 8.6 7.0 8.3 11.7 11.7 17.6 7.5 14.3 10.4 22.7 8.1 35.7 7.3 6.7 34.5 7.8 8.2 8.3 167.3 56.2 130.8 83.6 18.8 20.1 103.0 78.9 49.9 123.6 135.8 84.8 77.9 119.5 177.4 38.0 118.0 86.1 116.5 77.5 151.1 180.5 102.5 123.3 86.3 86.3 14.6 131.8 79.5 17.3 27.5 84.9 66.1 27.6 42.0 183.8 97.9 165.4 85.3 79.7 167.2 122.8 116.0 148.1 76.0 129.9 112.5 164.3 44.9 60.7 126.3 63.3 97.3 107.6 90.3 97.6 183.0 123.7 19.6 74.4 93.3 125.8 239.9 91.9 216.9 398.9 65.3 142.8 100.0 0.0 2.8 9.7 11.5 4.2 11.1 13.1 11.4 12.0 5.0 15.1 11.2 10.2 0.6 9.8 14.7 9.6 21.8 7.7 7.3 7.6 8.9 11.9 7.5 7.5 7.3 7.4 7.6 7.5 8.1 8.3 5.1 0.0 2.2 3.3 14.0 6.0 15.3 18.1 5.2 16.1 4.1 8.1 7.5 5.7 9.3 11.0 0.0 43.0 9.7 4.4 5.9 15.3 27.3 5.6 7.0 6.1 1.2 46.3 5.2 16.6 55.7 8.3 6.6 6.0 8.2 25.3 6.1 3.0 23.9 8.4 4.4 7.1 10.2 2.6 4.9 10.0 10.5 6.2 1.8 4.7 12.2 14.9 9.2 2.5 4.3 9.2 4.1 7.9 23.8 3.8 2.8 7.9 7.9 14.4 6.6 10.2 13.1 86.7 50.5 7.9 3.0 11.2 9.6 8.8 13.9 4.7 RFC5 RFC36 ENSG00000111445 "Replication factor C subunit 5" P40937 12 118013588-118033130 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041037 Supported Approved Nucleoplasm NA NA 6500 "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA041037: AB_10805834" "unprognostic (9.63e-2)" "prognostic favorable (8.05e-5)" "unprognostic (5.12e-3)" "unprognostic (2.25e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-2)" "unprognostic (1.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.35e-3)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.44e-1)" "unprognostic (2.15e-1)" "unprognostic (2.70e-1)" "unprognostic (5.06e-1)" 5.9 5.8 3.7 10.5 4.4 33.8 10.7 5.9 4.9 8.6 4.2 10.3 9.8 11.1 5.4 9.3 9.5 6.7 5.4 6.0 2.9 8.7 13.0 6.8 16.4 3.3 3.2 15.6 7.6 7.1 4.7 7.3 3.2 7.9 12.6 11.5 5.8 8.0 5.6 12.9 9.1 7.7 3.8 8.0 7.2 8.3 3.7 23.4 10.3 4.7 16.1 6.3 7.1 4.3 52.8 49.3 49.1 28.1 12.2 14.7 58.3 38.4 24.0 66.6 49.9 50.2 21.4 56.4 25.9 18.1 42.0 47.2 66.9 34.0 63.2 42.1 58.1 43.9 40.7 36.5 7.6 70.7 38.1 7.8 12.2 50.0 16.8 30.4 28.6 70.3 62.6 21.6 33.3 50.3 93.2 59.2 40.5 29.8 46.1 68.1 61.2 55.3 30.7 47.7 67.5 30.7 62.2 18.2 24.1 30.4 64.4 30.0 13.7 36.9 42.5 50.4 69.5 36.2 51.7 76.9 36.4 51.7 66.1 16.6 5.0 3.6 8.6 8.4 7.6 10.7 10.3 7.4 7.2 9.1 8.0 6.9 5.6 7.9 4.9 6.0 11.4 6.5 3.7 4.4 5.9 4.9 6.0 2.9 3.3 3.2 3.2 3.8 3.7 4.3 4.0 0.0 3.3 4.6 5.6 8.4 6.9 7.1 4.0 4.2 5.2 4.7 3.1 4.3 4.6 9.2 2.1 21.0 4.7 3.6 9.8 8.9 3.0 6.0 6.3 4.3 4.2 45.7 11.8 6.3 25.2 6.4 4.1 6.5 5.7 14.0 3.3 6.0 9.1 1.7 7.3 6.9 4.1 3.2 3.1 2.7 4.1 4.9 0.0 3.7 3.8 9.5 2.1 2.5 5.5 4.1 4.0 8.2 16.4 2.3 3.2 6.6 11.0 6.0 0.0 5.3 8.4 13.4 9.1 9.5 5.4 8.9 7.9 18.7 10.6 4.2 RFESD ENSG00000175449 "Rieske Fe-S domain containing" Q8TAC1 5 95646754-95684773 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.9" "Cell type enriched" "Detected in many" 7 "Erythroid cells: 278.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 41.3;K-562: 78.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016546 Uncertain Approved Nucleoplasm NA NA 48000 "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB016546: AB_630417" "unprognostic (1.15e-1)" "unprognostic (5.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.37e-2)" "unprognostic (6.07e-3)" "unprognostic (2.72e-1)" "unprognostic (1.33e-3)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (9.91e-2)" "unprognostic (8.24e-3)" "unprognostic (4.89e-2)" "unprognostic (5.83e-3)" "unprognostic (6.78e-2)" "unprognostic (9.03e-2)" "unprognostic (9.35e-2)" "unprognostic (1.09e-1)" 1.7 2.3 1.3 1.1 1.7 26.9 2.8 2.1 3.4 2.2 1.8 1.8 1.2 2.0 4.4 2.4 2.0 1.2 3.5 1.4 1.6 2.5 2.5 1.5 3.1 1.8 1.6 2.9 3.6 3.9 2.8 1.6 1.7 3.1 1.4 3.6 4.7 1.4 5.8 7.6 1.4 1.4 1.6 2.4 2.5 12.2 1.7 4.9 3.3 3.5 3.2 2.3 1.9 2.2 3.6 5.5 1.0 3.5 3.4 6.2 0.0 1.9 2.9 3.1 3.1 4.4 3.8 5.8 3.8 1.6 7.3 5.2 3.8 3.0 3.3 8.7 3.3 41.3 5.2 1.6 4.3 3.8 4.2 2.8 5.5 4.0 3.6 2.8 3.1 17.1 78.3 4.5 4.9 2.4 12.4 16.4 4.4 1.6 5.2 6.0 0.7 2.6 1.1 2.1 5.3 3.8 5.4 2.4 0.0 0.3 2.8 2.0 1.6 3.9 3.1 2.9 3.4 3.9 10.1 4.7 3.4 4.5 2.1 0.0 0.7 0.4 3.6 0.9 9.6 3.9 8.7 6.2 1.6 3.3 12.7 7.5 0.0 6.1 0.9 1.9 5.4 2.7 1.3 1.7 2.1 3.4 1.4 1.6 1.8 1.6 1.7 1.6 1.7 2.2 2.0 12.8 3.3 1.6 2.8 3.2 4.5 6.0 3.4 2.1 2.3 3.4 7.8 0.0 5.5 1.8 0.0 3.5 4.2 0.5 1.9 2.4 18.2 2.3 2.4 1.4 0.0 278.7 1.6 1.8 12.1 3.2 2.0 1.8 3.8 2.0 2.9 2.1 3.8 1.7 1.9 1.1 14.2 1.6 0.8 8.5 1.8 1.2 0.0 2.8 2.3 3.8 3.1 0.0 1.7 1.7 0.3 1.2 1.0 2.5 0.9 2.9 5.3 1.9 6.6 2.8 2.7 37.2 14.3 4.5 6.8 2.1 4.6 2.5 1.2 2.5 RGL3 FLJ32585 ENSG00000205517 "Ral guanine nucleotide dissociation stimulator like 3" Q3MIN7 19 11384341-11419328 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.1;parathyroid gland: 45.9;thyroid gland: 64.9" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Collecting duct cells: 51.5;Gastric mucus-secreting cells: 48.4;Sertoli cells: 39.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;CACO-2: 10.4;RT4: 22.0;SK-BR-3: 9.7;T-47d: 15.9" "Region enriched" "Detected in many" 6 "cerebellum: 9.0" "Low region specificity" "Detected in many" "HPA042763, HPA043615, HPA064578" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA042763: AB_10968569, HPA043615: AB_10959470, HPA064578: " "prognostic favorable (7.35e-4)" "unprognostic (3.12e-2)" "unprognostic (2.92e-1)" "unprognostic (5.69e-2)" "unprognostic (2.08e-1)" "unprognostic (6.60e-2)" "unprognostic (3.82e-2)" "unprognostic (5.31e-2)" "unprognostic (1.24e-2)" "unprognostic (1.48e-2)" "unprognostic (3.19e-3)" "unprognostic (5.99e-2)" "prognostic favorable (6.61e-4)" "unprognostic (4.17e-2)" "unprognostic (3.37e-1)" "unprognostic (3.21e-2)" "unprognostic (7.12e-3)" 7.3 11.5 1.8 0.7 1.6 0.0 7.4 1.9 2.5 13.3 6.9 2.9 1.4 4.8 9.5 1.1 9.5 2.1 9.2 2.2 2.2 41.1 10.6 8.9 0.6 2.7 2.4 2.5 21.0 45.9 15.4 5.6 2.8 6.5 1.3 0.8 5.9 9.4 2.0 1.3 1.8 0.8 1.7 8.2 13.8 0.6 2.9 0.2 64.9 0.6 0.3 5.3 5.7 2.3 0.0 0.6 0.0 0.1 1.1 0.2 17.7 1.1 1.4 0.6 2.0 10.4 7.4 0.0 6.5 1.3 2.6 4.6 0.0 0.0 0.1 0.0 0.0 0.1 4.2 3.3 2.7 0.0 0.0 0.0 0.1 0.1 0.0 4.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.9 1.4 0.0 0.7 2.2 6.3 22.0 1.0 5.2 0.2 9.7 3.3 3.7 15.9 0.0 0.0 3.3 0.0 2.5 0.9 0.0 0.6 1.0 0.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 1.6 1.9 2.5 2.2 2.2 2.7 2.4 2.8 1.7 2.9 2.3 3.1 19.2 21.0 32.3 1.1 0.1 2.1 0.4 1.8 0.3 3.3 4.6 4.6 12.8 12.4 51.5 0.0 12.9 0.0 2.2 11.7 8.6 0.0 14.8 9.6 5.8 10.3 0.0 0.5 4.2 11.9 4.1 48.4 18.4 1.3 3.1 26.0 5.8 3.0 0.0 0.6 7.7 2.0 7.4 0.3 0.2 3.7 1.5 5.4 4.7 0.0 16.9 0.0 1.5 0.5 5.7 5.3 0.4 0.6 1.4 0.0 4.6 1.7 0.6 39.5 9.9 18.7 0.6 1.7 0.0 0.0 12.0 0.2 0.8 2.4 2.0 RGMA RGM ENSG00000182175 "Repulsive guidance molecule BMP co-receptor a" Q96B86 15 93035273-93089204 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3;skeletal muscle: 199.1" "Cell type enhanced" "Detected in many" "Astrocytes: 143.3;Leydig cells: 119.0;Peritubular cells: 116.9;Prostatic glandular cells: 61.3;Skeletal myocytes: 69.3;Squamous epithelial cells: 58.3" "Cancer enriched" "Detected in many" 6 "glioma: 26.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 50.0;BEWO: 14.6;MOLT-4: 15.5;NTERA-2: 22.2;REH: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012343, HPA039880, HPA044222" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" NA NA 2000000 "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "CAB012343: AB_777667, HPA039880: AB_2676723, HPA044222: AB_2678861" "unprognostic (3.21e-2)" "unprognostic (1.59e-1)" "unprognostic (8.85e-2)" "unprognostic (3.96e-3)" "unprognostic (5.73e-2)" "unprognostic (4.72e-3)" "unprognostic (2.53e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (6.25e-2)" "unprognostic (3.59e-4)" "unprognostic (8.11e-2)" "unprognostic (2.92e-2)" "unprognostic (1.73e-1)" "unprognostic (7.98e-5)" 30.2 3.2 62.1 22.5 73.8 0.4 30.3 72.5 59.1 55.9 7.7 79.4 9.9 50.9 2.9 57.4 39.9 7.7 29.4 60.4 68.0 3.6 0.6 4.6 2.4 126.3 113.9 38.5 11.4 0.8 6.9 1.3 70.4 12.8 6.2 1.0 24.2 6.4 199.1 17.1 42.9 60.6 91.5 1.3 73.6 33.5 120.6 2.6 10.0 45.0 3.4 10.0 29.2 62.8 2.1 0.3 50.0 0.8 10.3 5.7 14.6 0.3 0.0 0.0 0.0 0.6 0.6 0.1 0.2 0.4 0.0 3.4 8.4 0.2 0.0 0.0 9.2 0.1 0.3 0.0 0.0 0.1 0.2 6.1 0.2 0.0 0.0 0.3 0.0 0.9 0.0 0.1 0.0 1.0 15.5 0.2 22.2 0.1 0.0 13.1 11.4 0.1 0.0 0.5 5.1 3.0 0.5 0.2 0.0 2.6 4.0 2.7 0.0 0.1 10.4 0.3 0.1 0.1 0.0 0.2 0.2 0.2 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 62.1 73.8 72.5 59.1 60.4 68.0 126.3 113.9 70.4 91.5 120.6 62.8 4.2 0.0 1.5 143.3 0.5 5.5 20.4 10.2 40.5 1.9 7.5 4.4 4.4 0.0 3.9 0.0 2.1 4.4 0.5 0.3 0.0 6.5 1.2 0.6 10.9 2.7 0.0 0.4 16.8 0.7 1.2 40.5 1.5 2.3 0.0 0.6 1.8 0.3 2.1 0.0 2.8 0.0 12.2 2.5 2.3 6.4 119.0 1.6 3.6 9.4 0.6 4.5 0.0 11.1 1.6 0.4 0.0 116.9 0.1 61.3 0.0 0.1 1.3 1.2 13.1 69.3 20.3 0.9 43.8 58.3 2.8 2.5 1.4 0.1 0.1 29.2 RGMB "DRAGON, FLJ90406" ENSG00000174136 "Repulsive guidance molecule BMP co-receptor b" Q6NW40 5 98768650-98798643 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 63.9;Undifferentiated cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 3.3" "Group enriched" "Detected in many" 12 "B-cells: 1.6;T-cells: 3.3" "Cell line enhanced" "Detected in many" "BJ: 285.8;BJ hTERT+: 142.9;fHDF/TERT166: 178.0;HBF TERT88: 222.5;LHCN-M2: 167.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016993 Approved Nucleoplasm NA NA 560000 "Cluster 32: T-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA016993: AB_1856216" "unprognostic (1.50e-2)" "unprognostic (3.77e-2)" "unprognostic (9.03e-2)" "unprognostic (8.92e-2)" "unprognostic (2.88e-1)" "unprognostic (5.27e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (8.24e-2)" "unprognostic (2.19e-1)" "unprognostic (3.60e-3)" "unprognostic (9.00e-2)" "unprognostic (3.88e-2)" "unprognostic (3.90e-2)" "unprognostic (6.40e-2)" "unprognostic (4.20e-2)" "unprognostic (3.78e-3)" 8.8 7.7 14.8 7.2 18.4 0.3 9.1 11.4 17.4 9.3 5.7 20.5 21.4 9.2 6.0 11.8 11.1 7.5 10.2 17.4 15.1 4.7 6.0 8.1 3.7 12.9 16.0 21.8 11.2 9.3 11.4 5.5 27.1 20.7 33.3 3.8 21.8 13.9 24.8 33.8 26.2 10.9 12.2 6.0 41.7 10.5 22.3 2.6 11.5 16.1 4.5 10.8 9.5 14.9 7.3 5.2 87.8 8.1 26.2 44.5 9.1 285.8 142.9 138.5 97.6 4.4 3.5 4.2 10.2 178.0 9.7 7.5 10.4 26.0 222.5 12.5 10.2 0.0 7.1 4.9 12.6 0.9 0.1 37.1 9.4 71.1 28.2 37.6 26.3 13.6 0.0 3.5 167.1 8.1 0.1 0.1 6.0 3.3 14.0 11.4 50.7 7.9 5.4 8.4 35.6 18.0 3.9 9.4 14.1 4.4 7.5 0.4 57.4 86.7 14.2 54.1 133.5 6.0 9.1 5.8 31.9 0.1 19.1 0.0 0.0 0.2 0.1 0.0 0.7 1.1 1.5 0.6 0.0 1.6 3.3 1.5 0.1 0.1 0.0 0.0 2.4 0.8 14.8 18.4 11.4 17.4 17.4 15.1 12.9 16.0 27.1 12.2 22.3 14.9 8.6 16.0 4.1 7.5 12.7 31.0 15.3 6.0 44.3 5.7 17.8 12.4 14.3 7.2 5.3 9.2 16.7 4.5 0.4 12.8 1.9 5.0 63.9 10.2 12.7 10.3 21.8 0.0 20.8 5.3 6.2 19.1 18.8 18.0 0.0 4.0 9.3 8.2 2.1 0.0 23.6 44.6 4.1 1.0 7.2 16.9 9.0 2.4 12.4 5.6 0.7 1.7 0.0 35.2 6.6 8.4 16.3 7.2 1.7 16.1 11.9 1.6 6.1 4.0 0.0 20.3 13.1 7.4 17.5 27.0 24.4 1.8 2.9 5.4 88.9 17.4 RGS12 ENSG00000159788 "Regulator of G protein signaling 12" O14924 4 3293028-3439913 "Plasma proteins, Predicted intracellular proteins" Transcription "GTPase activation, Repressor, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 142.0;Inhibitory neurons: 170.1;Suprabasal keratinocytes: 110.0;Urothelial cells: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054646, HPA067421" Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" Cytosol "HPA054646: AB_2682555, HPA067421: AB_2685836" "unprognostic (2.08e-1)" "unprognostic (1.71e-3)" "unprognostic (7.50e-2)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "prognostic favorable (7.03e-4)" "unprognostic (3.43e-2)" "unprognostic (1.93e-1)" "unprognostic (1.76e-1)" "unprognostic (9.02e-2)" "unprognostic (1.70e-2)" "unprognostic (2.13e-1)" "prognostic favorable (8.43e-4)" "unprognostic (2.54e-1)" "unprognostic (2.60e-1)" "unprognostic (5.92e-2)" "unprognostic (1.11e-2)" 8.4 6.5 13.6 2.9 46.6 2.3 8.7 10.2 20.5 16.1 10.5 8.3 4.8 8.6 4.7 30.4 9.9 3.9 6.7 12.9 8.5 11.1 17.3 10.6 3.5 9.5 8.5 12.5 4.9 3.3 13.8 3.7 8.2 16.6 1.9 3.8 9.4 4.7 12.3 20.7 6.2 2.6 7.8 6.0 6.7 10.3 8.7 3.6 8.0 4.6 3.3 10.4 20.2 10.5 4.8 6.0 11.9 8.6 3.9 3.1 4.9 5.1 4.1 5.2 3.8 4.9 2.8 1.1 3.1 4.5 7.6 4.6 2.3 16.3 1.7 0.1 1.9 0.5 3.6 12.0 3.5 0.3 6.5 2.6 10.9 2.7 3.6 4.6 11.5 4.2 5.6 0.2 4.8 4.1 0.8 13.1 5.6 2.7 5.7 12.3 4.6 4.0 2.7 14.1 13.3 13.8 3.2 2.2 11.4 2.9 5.4 8.2 8.7 10.0 6.5 2.0 5.5 5.9 4.9 2.7 5.9 7.2 7.3 0.4 0.3 0.0 0.2 1.1 0.0 0.0 0.2 0.1 0.4 0.2 0.3 0.1 0.4 0.0 1.1 0.2 0.2 0.2 13.6 46.6 10.2 20.5 12.9 8.5 9.5 8.5 8.2 7.8 8.7 10.5 16.1 6.4 6.4 66.9 2.6 84.4 142.0 69.3 71.2 17.3 11.0 14.9 8.6 8.6 28.6 5.5 29.2 6.2 1.3 6.4 3.9 10.4 5.0 22.8 13.3 26.6 14.9 4.8 44.3 10.4 1.3 14.6 7.7 11.8 14.0 57.7 27.8 28.8 20.8 10.1 170.1 10.8 8.2 12.4 11.3 5.5 14.9 21.7 17.8 47.8 7.8 29.3 2.1 71.4 25.5 14.7 2.7 7.9 0.8 53.9 6.0 23.9 34.6 18.9 0.0 12.5 12.7 24.0 15.3 84.4 110.0 6.7 4.3 11.8 9.0 153.8 RGS13 ENSG00000127074 "Regulator of G protein signaling 13" O14921 1 192636138-192660311 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 48.0" "Cell type enriched" "Detected in some" 16 "granulocytes: 520.0" "Cancer enhanced" "Detected in single" "stomach cancer: 0.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 39 "basophil: 6.8" "Lineage enriched" "Detected in single" 39 "granulocytes: 6.8" "Cell line enriched" "Detected in some" 20 "Daudi: 47.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA076656 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 60: Granulocytes - Receptor signaling" "HPA076656: " "unprognostic (1.99e-2)" "unprognostic (6.08e-3)" "unprognostic (3.25e-4)" "unprognostic (1.86e-1)" "unprognostic (2.31e-1)" "unprognostic (4.37e-5)" "unprognostic (1.93e-1)" "unprognostic (2.08e-3)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (7.39e-2)" "unprognostic (1.28e-1)" "unprognostic (8.65e-2)" "unprognostic (3.42e-1)" "unprognostic (2.35e-1)" "unprognostic (6.86e-2)" "unprognostic (1.96e-1)" 0.5 0.0 0.0 9.5 0.0 0.7 2.3 0.0 0.0 1.6 0.0 2.3 3.1 1.0 0.7 1.7 0.3 3.7 0.1 0.0 0.0 0.0 0.0 3.9 48.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.2 1.6 0.0 0.3 0.6 0.0 0.3 5.7 1.2 0.0 0.3 2.0 0.1 0.1 1.3 0.0 0.2 35.1 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 30.8 0.0 4.8 1.9 2.1 0.0 0.0 0.0 0.1 0.3 0.3 0.0 1.3 0.0 0.0 0.0 2.9 0.1 0.0 0.1 0.0 0.0 0.0 0.3 7.1 0.0 0.2 0.0 0.0 0.9 12.2 0.0 520.0 0.0 0.0 0.0 0.3 0.0 0.6 0.6 0.0 0.6 7.1 0.0 0.0 3.8 7.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 3.9 1.7 0.2 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.3 0.0 7.9 0.5 1.6 0.1 RGS14 ENSG00000169220 "Regulator of G protein signaling 14" O43566 5 177357924-177372596 "Predicted intracellular proteins" "Cell cycle, Cell division" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 110.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 72.8;Proximal tubular cells: 113.7;Squamous epithelial cells: 95.8;Suprabasal keratinocytes: 115.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 110.4;cerebral cortex: 67.9;hippocampal formation: 56.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 112.5;HMC-1: 95.4;NB-4: 44.8;RPMI-8226: 57.9" "Group enriched" "Detected in many" 10 "amygdala: 66.0;basal ganglia: 57.9;cerebral cortex: 46.8;hippocampal formation: 93.6;white matter: 23.8" "Region enhanced" "Detected in many" "basal ganglia: 102.1" "HPA046847, HPA061819" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Intermediate filaments" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Vesicles, Plasma membrane, Intermediate filaments" "HPA046847: AB_2679836, HPA061819: " "unprognostic (6.05e-3)" "unprognostic (1.65e-2)" "unprognostic (8.57e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.97e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.95e-2)" "unprognostic (4.34e-2)" "unprognostic (2.04e-3)" "unprognostic (2.71e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.17e-2)" "unprognostic (2.78e-2)" 3.5 2.8 16.0 13.9 110.4 22.4 2.9 0.0 67.9 3.1 1.8 3.7 6.3 2.3 0.4 10.0 7.7 4.3 1.3 56.4 4.5 8.5 28.7 5.5 18.1 0.0 0.4 1.1 3.7 1.5 2.4 1.4 0.1 3.5 0.9 0.0 6.2 2.1 2.6 6.1 11.0 1.8 0.1 27.7 4.9 1.9 15.2 16.3 6.1 0.9 6.6 4.1 5.0 3.2 5.4 1.1 2.3 1.4 0.1 0.0 3.7 0.2 0.0 0.5 0.6 3.7 10.4 13.3 7.3 0.4 1.3 10.6 0.2 3.8 0.0 112.5 0.5 20.7 1.0 4.7 0.9 16.3 95.4 1.8 1.1 0.6 0.7 1.4 0.6 14.9 3.5 26.5 0.2 0.4 21.7 44.8 1.7 5.4 2.8 10.2 0.3 57.9 1.5 1.6 0.4 1.9 0.4 0.4 8.8 0.0 3.5 25.2 1.1 0.2 1.9 0.0 9.7 13.9 7.1 5.8 1.6 30.3 2.4 70.6 39.9 148.8 62.4 37.9 63.0 27.7 57.9 57.8 39.8 26.6 47.4 43.1 140.0 23.6 41.2 17.6 60.9 43.9 16.0 110.4 0.0 67.9 56.4 4.5 0.0 0.4 0.1 0.1 15.2 3.2 5.3 6.4 4.4 2.6 27.3 68.8 23.9 15.4 72.8 0.7 8.9 11.8 2.3 37.1 5.6 11.0 2.1 3.9 41.4 4.2 31.3 11.4 0.6 19.5 2.0 6.5 4.8 7.4 4.6 16.7 10.4 5.4 12.2 8.1 24.7 2.8 8.2 64.0 26.1 0.0 1.5 10.0 10.2 17.0 23.3 1.5 2.8 18.2 21.4 6.5 18.1 9.9 48.4 0.5 0.3 12.8 17.2 2.2 18.0 14.1 16.8 113.7 11.7 2.0 0.0 1.6 4.6 0.1 20.3 95.8 115.1 3.3 51.2 1.1 4.4 20.0 RGS9BP "FLJ45744, PERRS, R9AP" ENSG00000186326 "Regulator of G protein signaling 9 binding protein" Q6ZS82 19 32675848-32678300 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 28.9;retina: 17.4;skeletal muscle: 9.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 29.0;Cone photoreceptor cells: 56.3;Rod photoreceptor cells: 75.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.3;HMC-1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA049791 Enhanced Approved "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA049791: AB_2680884" "unprognostic (2.82e-2)" "unprognostic (6.99e-3)" "unprognostic (2.44e-3)" "unprognostic (1.20e-7)" "unprognostic (1.49e-1)" "unprognostic (1.21e-2)" "unprognostic (1.17e-2)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (6.71e-2)" "unprognostic (6.74e-2)" "unprognostic (3.89e-2)" "unprognostic (1.63e-3)" "unprognostic (2.29e-1)" "unprognostic (8.22e-2)" "unprognostic (5.23e-2)" "unprognostic (5.34e-2)" 0.0 0.1 0.8 0.0 0.7 0.0 0.0 0.8 0.8 0.0 28.9 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.3 3.3 0.9 0.3 0.0 0.3 0.0 1.1 1.4 0.0 0.0 0.2 0.2 0.0 0.9 0.2 0.0 17.4 0.1 0.1 9.0 0.1 0.0 0.0 0.5 0.0 0.1 0.4 1.5 0.1 0.0 3.2 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.5 0.3 0.1 0.3 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.3 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.1 6.3 0.1 0.0 0.1 0.1 1.6 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.4 0.8 0.1 0.2 0.0 1.0 0.0 0.0 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.6 0.3 0.0 0.2 0.3 0.1 0.1 0.3 0.4 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.8 0.8 3.3 0.9 1.1 1.4 0.9 0.5 1.5 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 29.0 0.4 0.4 4.6 0.0 0.0 1.8 56.3 0.3 0.6 0.5 0.0 0.0 5.1 0.2 0.1 0.7 0.0 0.8 0.0 0.0 0.2 0.2 0.0 0.4 0.0 1.8 0.7 0.0 0.2 1.7 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.4 0.9 0.0 75.4 0.0 0.4 0.2 0.5 0.4 0.0 0.0 0.0 0.1 1.1 0.4 0.0 RHBDF2 "FLJ22341, iRhom2, RHBDL5, RHBDL6, TOC, TOCG" ENSG00000129667 "Rhomboid 5 homolog 2" Q6PJF5 17 76470891-76501790 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 58.4;Kupffer cells: 57.3;NK-cells: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 75.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA018080 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 57: B-cells - Immune response" "HPA018080: AB_2178634" "unprognostic (1.19e-1)" "unprognostic (8.71e-2)" "unprognostic (1.59e-2)" "unprognostic (5.11e-3)" "unprognostic (4.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-3)" "unprognostic (9.79e-3)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.96e-11)" "unprognostic (5.24e-2)" "unprognostic (2.14e-2)" "unprognostic (1.61e-2)" "unprognostic (1.14e-1)" 18.3 10.1 9.4 31.2 8.6 29.7 13.6 11.7 11.0 8.8 11.6 9.0 6.5 7.4 1.6 23.9 10.1 10.3 10.3 9.7 12.1 10.9 6.3 24.8 27.6 26.6 17.2 8.0 19.5 3.1 5.3 9.7 22.4 9.1 4.4 2.9 11.6 2.6 13.5 29.1 26.6 6.4 20.9 42.2 10.5 3.0 30.0 6.5 12.3 3.1 21.3 11.0 15.7 28.8 38.3 43.3 1.3 10.7 0.4 1.1 30.1 8.6 26.9 6.7 9.1 13.3 45.0 41.5 28.6 10.9 39.0 29.9 7.3 40.8 6.2 7.1 13.6 2.8 3.5 21.8 25.6 1.8 5.9 4.5 20.2 18.1 20.7 15.4 20.3 5.9 4.3 18.3 4.6 30.7 4.3 4.7 6.7 25.7 26.1 10.3 0.4 75.3 17.8 14.0 9.2 12.6 9.9 28.7 38.7 8.5 24.7 11.4 32.4 0.6 14.4 0.7 11.0 44.3 22.6 33.7 24.3 11.2 27.1 6.3 13.4 4.3 8.0 13.1 5.5 12.7 2.1 5.8 6.5 7.4 1.5 3.6 10.2 4.9 12.2 10.0 1.1 8.8 9.4 8.6 11.7 11.0 9.7 12.1 26.6 17.2 22.4 20.9 30.0 28.8 22.3 6.4 6.9 2.3 58.4 17.6 15.3 35.0 8.0 4.2 4.7 5.5 3.3 18.6 19.2 3.7 2.1 1.0 47.1 2.0 0.0 21.3 0.5 4.2 0.8 15.3 1.8 1.3 0.6 9.8 2.2 4.7 7.7 6.6 0.0 15.4 7.9 3.4 37.6 0.0 0.5 4.1 6.1 57.3 42.7 0.7 0.9 48.8 10.6 38.4 40.1 1.1 64.9 1.0 0.1 14.2 4.8 0.4 36.5 20.4 1.9 1.8 16.2 1.4 6.6 3.6 3.2 0.7 7.1 9.9 29.3 1.6 22.3 2.8 7.8 20.4 RHBDL2 FLJ20435 ENSG00000158315 "Rhomboid like 2" Q9NX52 1 38885807-38941830 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 74.6;Club cells: 44.8;Distal enterocytes: 52.2;Ionocytes: 46.8;Oligodendrocytes: 53.9;Pancreatic endocrine cells: 53.0;Urothelial cells: 49.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 12.7;CAPAN-2: 41.7;HaCaT: 21.7;RT4: 40.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043807 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA043807: AB_10961118" "unprognostic (3.34e-2)" "unprognostic (2.96e-1)" "unprognostic (4.57e-2)" "unprognostic (2.56e-1)" "unprognostic (7.26e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-3)" "unprognostic (5.81e-2)" "unprognostic (2.36e-1)" "unprognostic (2.87e-1)" "unprognostic (4.07e-3)" "unprognostic (1.23e-1)" "unprognostic (7.47e-9)" "unprognostic (1.11e-2)" "unprognostic (2.46e-1)" "unprognostic (4.12e-2)" "unprognostic (4.20e-2)" 2.2 0.4 4.1 1.7 8.8 0.4 2.0 5.6 7.1 4.3 0.3 18.0 1.3 0.6 0.2 24.4 1.1 3.4 7.7 4.0 4.9 0.9 0.4 1.0 0.8 10.0 9.5 0.3 0.6 0.3 1.3 1.1 7.3 1.8 18.0 1.1 7.8 0.5 0.5 16.6 0.8 1.1 4.1 0.4 15.7 7.3 7.4 0.7 0.7 0.0 7.1 9.7 12.8 11.4 12.7 4.3 0.4 0.2 0.2 1.2 1.2 0.7 0.1 0.9 0.1 0.9 41.7 0.3 3.0 6.3 4.2 21.7 0.0 7.1 0.6 0.3 0.2 0.2 2.9 2.5 0.5 0.1 0.5 0.9 1.0 6.0 0.1 4.0 1.0 0.4 0.0 0.4 0.9 0.0 0.1 0.3 0.2 1.3 1.2 0.2 0.2 0.0 0.0 40.4 0.4 0.3 5.0 11.4 0.4 0.6 5.6 0.4 0.9 4.4 0.5 0.3 0.3 0.4 0.5 0.5 4.1 0.8 0.2 1.5 0.6 0.4 0.2 0.4 0.1 0.7 0.2 0.1 0.7 0.3 0.2 0.2 1.7 0.3 0.2 0.7 0.3 0.3 4.1 8.8 5.6 7.1 4.0 4.9 10.0 9.5 7.3 4.1 7.4 11.4 1.3 0.0 0.5 11.1 0.7 17.7 8.0 74.6 5.2 2.7 3.9 2.4 0.4 5.7 44.8 3.7 0.0 0.4 0.2 52.2 0.0 12.4 3.9 4.7 3.4 1.4 2.4 0.0 19.0 15.8 0.3 2.1 27.5 8.4 4.5 1.6 1.8 0.0 0.2 1.7 21.9 17.3 46.8 0.0 2.7 1.0 0.6 0.4 1.8 4.7 0.6 1.3 0.0 10.6 53.9 53.0 22.3 0.0 0.2 13.4 0.2 0.3 33.2 1.8 6.6 1.2 4.0 0.3 0.1 19.0 28.4 0.7 0.5 0.2 30.2 49.9 RHBDL3 "RHBDL4, VRHO" ENSG00000141314 "Rhomboid like 3" P58872 17 32265832-32324659 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 23.0;heart muscle: 13.8;retina: 26.1" "Cell type enhanced" "Detected in some" "Astrocytes: 41.8;Excitatory neurons: 46.8;Horizontal cells: 102.6;Oligodendrocyte precursor cells: 75.9;Rod photoreceptor cells: 34.2" "Cancer enriched" "Detected in some" 4 "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;AF22: 4.7;AN3-CA: 3.8;GAMG: 5.5;HDLM-2: 6.0;NTERA-2: 6.5;U-2 OS: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA059607 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA059607: AB_2684081" "unprognostic (7.70e-2)" "unprognostic (3.71e-2)" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.91e-1)" "unprognostic (2.83e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (1.75e-2)" "unprognostic (4.19e-2)" "unprognostic (2.18e-3)" "unprognostic (2.11e-1)" "unprognostic (1.23e-1)" "unprognostic (8.87e-2)" 0.4 5.1 9.4 0.4 10.6 0.1 0.4 14.1 23.0 2.2 3.4 0.8 0.2 1.6 0.7 0.5 2.3 0.2 13.8 13.6 9.6 0.6 0.0 0.3 0.1 14.2 19.0 2.2 0.5 0.8 2.9 0.2 15.9 1.6 0.5 26.1 0.3 3.0 0.1 0.3 0.4 0.7 12.1 0.1 0.7 2.0 11.6 0.2 0.3 0.1 0.2 2.3 1.8 14.8 0.0 4.6 4.7 3.8 0.7 0.0 0.1 0.2 0.5 1.4 1.7 0.0 0.0 0.0 0.2 0.5 5.5 0.0 1.2 0.0 0.3 6.0 1.5 0.8 3.1 0.2 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.2 0.0 0.3 0.5 0.0 0.3 0.1 0.1 0.0 6.5 0.0 0.0 0.8 0.0 0.0 0.0 2.6 0.1 1.3 0.6 0.1 0.1 1.5 0.3 0.0 0.0 0.0 4.4 0.2 2.2 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 10.6 14.1 23.0 13.6 9.6 14.2 19.0 15.9 12.1 11.6 14.8 0.6 0.0 0.0 41.8 0.0 0.4 0.5 0.0 0.0 12.1 0.8 0.6 7.4 0.0 0.0 0.0 6.2 1.5 0.1 0.0 0.0 0.1 3.2 0.3 0.2 0.7 0.0 0.0 46.8 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.4 0.0 0.4 102.6 15.2 0.4 0.0 0.3 0.3 2.4 0.9 0.1 0.0 4.7 0.0 7.4 0.0 75.9 4.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 34.2 0.0 0.1 0.5 0.1 1.2 0.0 0.1 0.5 0.1 0.0 0.0 0.6 RHBG SLC42A2 ENSG00000132677 "Rh family B glycoprotein" Q9H310 1 156369211-156385219 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 9.8" "Group enriched" "Detected in some" 4 "Granulosa cells: 89.9;Theca cells: 91.3" "Group enriched" "Detected in some" 5 "liver cancer: 14.2;renal cancer: 5.1;urothelial cancer: 4.1" "Region enriched" "Detected in single" 17 "cerebellum: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 2.9;Hep G2: 3.0;RT4: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042726, HPA048489" Enhanced Approved Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA042726: AB_2678131, HPA048489: AB_2680417" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" "unprognostic (4.55e-3)" "unprognostic (5.04e-2)" "unprognostic (2.95e-2)" "unprognostic (3.76e-3)" "unprognostic (2.00e-1)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.45e-1)" "unprognostic (3.72e-1)" "unprognostic (3.63e-2)" "unprognostic (4.91e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-3)" "prognostic favorable (8.06e-4)" 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.8 1.9 0.0 0.0 0.1 0.0 2.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 22.0 0.0 0.0 0.0 0.0 19.6 0.3 10.3 0.3 0.0 0.1 0.0 0.0 0.2 0.6 0.1 1.3 0.0 0.1 0.0 89.9 0.0 10.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.1 1.3 0.2 0.0 0.0 0.0 0.8 2.3 0.4 0.0 0.4 0.0 0.0 91.3 0.0 0.1 RHEBL1 "FLJ25797, MGC34869, RHEB2" ENSG00000167550 "RHEB like 1" Q8TAI7 12 49064676-49070025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Cell type enhanced" "Detected in many" "dendritic cells: 10.6;Granulosa cells: 12.2;NK-cells: 14.4;Plasma cells: 8.2;Respiratory ciliated cells: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 16.1" "Group enriched" "Detected in all" 5 "granulocytes: 16.1;T-cells: 10.4" "Cell line enhanced" "Detected in many" "HDLM-2: 30.8;U-266/84: 61.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA053111, HPA061001" Uncertain Uncertain Nucleoplasm,Centrosome NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Centrosome" "HPA053111: AB_2682047, HPA061001: AB_2684409" "unprognostic (2.94e-1)" "unprognostic (1.11e-3)" "unprognostic (2.36e-2)" "unprognostic (9.81e-3)" "unprognostic (8.76e-2)" "unprognostic (2.03e-2)" "unprognostic (3.03e-5)" "unprognostic (9.13e-2)" "unprognostic (9.02e-3)" "unprognostic (2.13e-1)" "unprognostic (3.98e-1)" "unprognostic (1.24e-1)" "unprognostic (1.13e-10)" "unprognostic (4.67e-2)" "unprognostic (1.11e-1)" "unprognostic (7.66e-2)" "unprognostic (2.07e-1)" 0.8 0.2 2.2 1.5 2.3 2.1 0.8 2.1 4.1 0.3 1.7 0.5 0.5 1.4 1.0 0.4 2.6 0.5 0.5 2.2 2.2 0.3 0.3 1.2 3.6 2.3 2.1 0.3 0.2 0.2 0.3 0.6 2.1 0.2 0.8 0.8 0.4 0.2 0.2 2.6 0.9 0.5 1.9 2.5 0.6 1.5 2.1 1.6 0.3 1.1 1.9 0.4 0.4 2.4 1.7 3.4 2.2 4.8 1.2 0.2 2.1 1.4 4.8 9.1 9.9 3.2 2.9 4.7 1.5 0.4 4.7 1.8 1.5 1.8 3.9 30.8 0.4 4.9 2.9 1.9 1.0 2.4 10.1 0.5 0.8 4.5 1.4 0.6 3.5 8.3 6.1 14.8 3.3 1.7 2.3 13.3 3.0 6.0 3.9 4.7 3.2 7.9 0.7 0.2 1.0 2.9 1.4 1.3 8.4 2.6 0.5 3.5 1.3 2.7 4.4 5.3 1.7 17.8 61.0 3.0 2.3 7.2 1.2 16.1 0.3 0.7 7.6 1.8 10.4 2.0 3.2 4.1 0.8 2.9 1.0 3.8 0.7 1.4 1.7 1.0 6.7 1.4 2.2 2.3 2.1 4.1 2.2 2.2 2.3 2.1 2.1 1.9 2.1 2.4 2.8 0.0 0.0 0.3 6.8 1.3 0.5 1.9 4.0 1.8 1.2 1.7 1.5 1.5 1.8 0.0 0.0 0.1 10.6 0.1 0.0 0.5 0.5 2.8 0.3 2.6 0.0 8.0 6.9 0.2 0.5 1.4 0.5 0.4 0.0 12.2 1.8 0.1 1.8 3.3 2.3 0.2 0.0 0.3 2.0 0.6 0.0 3.7 0.0 0.0 4.5 0.6 14.4 0.5 0.3 0.2 0.0 0.0 8.2 0.4 0.1 0.1 12.0 0.4 0.0 1.3 1.8 0.9 5.4 4.8 2.0 0.1 5.7 0.2 0.4 0.2 RHNO1 "C12orf32, HKMT1188, MGC13204, RHINO" ENSG00000171792 "RAD9-HUS1-RAD1 interacting nuclear orphan 1" Q9BSD3 12 2876258-2889524 "Predicted intracellular proteins" "Cell cycle, DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (3.90e-2)" "unprognostic (4.86e-2)" "unprognostic (6.48e-3)" "unprognostic (1.86e-1)" "unprognostic (5.15e-2)" "unprognostic (3.59e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (7.15e-2)" "unprognostic (1.19e-2)" "unprognostic (1.12e-3)" "unprognostic (4.83e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (5.74e-13)" "unprognostic (1.97e-1)" "unprognostic (1.64e-1)" "unprognostic (2.54e-2)" "unprognostic (4.53e-2)" 5.5 8.8 12.5 13.1 10.9 17.1 12.1 11.3 13.5 13.1 12.2 14.1 11.0 11.5 22.7 17.5 12.2 10.7 7.2 12.5 13.5 9.1 5.2 9.2 19.6 9.7 10.0 15.6 8.7 13.6 12.0 11.6 12.4 13.4 14.5 13.0 12.1 12.7 6.5 14.1 10.1 11.5 8.3 12.8 10.6 11.3 12.2 25.7 16.6 3.9 20.9 12.4 10.6 16.7 42.3 54.2 64.5 32.9 14.8 18.6 67.7 40.7 43.3 51.0 50.1 66.3 91.4 34.5 22.8 42.4 64.2 32.4 43.0 50.9 62.4 138.6 28.2 45.0 25.3 39.6 20.0 50.8 33.4 18.4 32.4 50.3 104.8 36.7 52.5 71.8 41.1 81.2 61.3 60.9 92.8 28.5 149.7 52.8 32.4 61.6 77.7 26.8 41.2 52.3 21.6 32.0 56.1 35.6 30.0 117.7 69.3 47.2 37.1 55.1 83.6 62.6 85.3 18.5 37.9 90.6 25.3 41.8 51.7 23.7 23.3 34.9 23.8 22.0 31.2 27.7 36.4 31.9 26.5 41.9 36.8 24.7 4.8 26.5 23.9 15.8 54.7 25.9 12.5 10.9 11.3 13.5 12.5 13.5 9.7 10.0 12.4 8.3 12.2 16.7 3.8 0.0 5.9 3.3 14.0 7.8 10.0 27.7 6.2 6.8 11.9 13.3 7.6 7.2 10.4 11.0 8.4 40.1 6.5 7.2 23.5 13.9 6.5 8.1 7.0 8.7 10.3 33.2 6.6 8.4 34.0 8.2 7.1 9.0 14.0 17.4 12.5 3.9 31.7 10.1 6.4 16.3 14.2 15.5 8.0 14.6 12.2 10.2 3.6 2.8 32.3 20.4 10.3 3.0 6.5 6.9 9.6 8.6 11.4 18.1 13.2 15.4 6.4 9.8 0.0 3.1 7.5 67.1 46.0 18.8 7.1 21.8 17.3 8.4 17.3 12.5 RHOD "ARHD, Rho, RhoHP1" ENSG00000173156 "Ras homolog family member D" O00212 11 67056847-67072017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 182.2;liver: 122.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 124.7;Ductal cells: 102.8;Exocrine glandular cells: 141.6;Pancreatic endocrine cells: 271.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 156.0;CAPAN-2: 109.2;HaCaT: 135.9;HBEC3-KT: 179.8;hTCEpi: 208.6;MCF7: 101.0;T-47d: 148.7" "Group enriched" "Detected in many" 4 "cerebellum: 14.9;pons and medulla: 5.1" "Low region specificity" "Detected in some" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (2.12e-2)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.89e-3)" "unprognostic (1.65e-1)" "unprognostic (3.61e-3)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (3.10e-4)" "unprognostic (5.85e-2)" "unprognostic (4.39e-2)" "unprognostic (1.38e-3)" "unprognostic (8.89e-2)" "unprognostic (2.56e-2)" "unprognostic (2.24e-1)" "unprognostic (5.89e-2)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" 13.0 2.5 3.3 2.5 3.0 0.0 13.9 4.0 4.7 36.7 18.1 9.1 9.1 12.5 1.1 182.2 11.4 6.6 53.4 3.5 2.7 24.0 122.9 8.9 1.1 3.5 2.9 11.8 36.2 24.8 15.6 7.3 3.1 18.0 1.2 0.8 34.9 7.1 28.2 58.6 7.3 3.3 2.8 2.6 15.6 4.9 2.7 1.4 23.0 5.0 6.0 7.8 60.1 2.5 156.0 12.2 0.8 15.8 2.3 1.7 23.1 13.7 22.5 8.2 8.1 11.4 109.2 0.0 24.6 16.1 0.0 135.9 1.6 179.8 1.5 0.0 0.5 0.0 62.6 1.3 21.7 0.1 0.2 21.4 208.6 2.5 54.2 10.1 8.3 0.0 0.0 10.6 2.5 101.0 0.2 0.1 17.8 16.6 62.6 0.0 0.0 0.3 76.3 11.2 1.0 0.0 70.9 4.0 6.1 2.9 148.7 0.5 5.1 0.1 0.4 2.2 0.8 0.0 3.5 0.2 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.0 4.0 4.7 3.5 2.7 3.5 2.9 3.1 2.8 2.7 2.5 6.6 16.0 4.4 0.7 1.3 32.9 34.6 124.7 56.9 0.2 38.8 57.7 28.2 28.6 29.0 16.5 0.0 29.9 0.6 67.7 45.0 102.8 16.7 6.5 8.1 7.2 4.2 3.6 0.4 141.6 34.1 14.8 24.5 9.7 0.0 8.0 5.7 46.3 3.6 0.0 0.3 4.5 10.2 1.0 4.0 9.4 11.8 1.0 8.8 1.0 0.6 13.6 0.0 0.5 0.2 271.3 66.1 22.2 1.7 61.0 90.8 24.7 19.3 0.6 0.0 2.1 9.1 0.9 4.7 55.4 57.7 36.0 2.8 1.5 6.6 71.8 RHOQ "ARHQ, RASL7A, TC10" ENSG00000119729 "Ras homolog family member Q" P17081 2 46541806-46584688 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 189.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.5;classical monocyte: 2.5;eosinophil: 4.2;intermediate monocyte: 2.7;memory B-cell: 1.7;myeloid DC: 1.6;naive B-cell: 2.4;neutrophil: 4.8;non-classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 164.0;ASC TERT1: 132.0;SK-MEL-30: 150.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044938 Approved Vesicles,Cytosol No No "Cluster 24: B-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "HPA044938: AB_2679149" "unprognostic (1.24e-1)" "unprognostic (1.30e-2)" "unprognostic (5.82e-2)" "unprognostic (2.07e-2)" "unprognostic (3.61e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.60e-5)" "unprognostic (2.01e-2)" "unprognostic (9.24e-2)" "unprognostic (2.11e-2)" "unprognostic (1.97e-1)" "unprognostic (5.43e-2)" "unprognostic (3.88e-3)" "unprognostic (1.39e-2)" "unprognostic (1.87e-1)" "unprognostic (7.68e-2)" "unprognostic (3.52e-2)" 96.9 35.7 34.8 30.1 40.1 12.4 64.8 38.9 41.4 59.6 43.9 67.0 11.0 53.2 67.7 18.9 59.3 26.7 196.8 34.3 44.7 44.3 22.6 56.0 23.8 40.9 44.2 40.8 28.6 50.4 29.5 28.6 38.9 50.6 13.5 27.7 32.7 36.5 162.4 28.1 35.3 38.4 39.2 42.7 32.8 10.1 36.8 9.9 39.1 181.3 19.1 62.8 44.7 43.5 12.3 12.4 21.0 28.6 164.0 132.0 3.7 32.8 84.1 16.2 24.4 6.2 4.1 28.7 34.0 58.5 52.4 5.8 20.6 9.8 29.3 10.2 15.3 8.2 9.8 20.9 81.8 8.8 10.7 118.1 17.3 20.1 22.5 39.0 19.3 3.1 12.1 44.0 35.2 8.1 6.9 17.9 20.8 8.9 14.4 5.3 34.5 10.1 23.1 22.4 15.3 50.3 11.6 16.4 150.8 32.9 9.0 20.7 13.2 50.1 44.8 49.3 14.1 48.5 17.7 28.4 73.6 22.1 18.4 1.5 2.5 4.2 0.4 2.7 0.3 1.7 0.2 0.4 1.6 2.4 0.0 0.3 4.8 0.3 1.9 0.6 0.3 0.7 34.8 40.1 38.9 41.4 34.3 44.7 40.9 44.2 38.9 39.2 36.8 43.5 27.9 57.7 22.4 65.3 38.1 22.4 31.0 18.1 11.4 21.1 30.4 22.4 189.2 14.3 22.1 20.2 10.4 14.6 32.2 1.0 17.6 21.4 30.8 22.1 90.2 23.4 6.0 2.1 12.8 32.0 3.6 82.8 4.1 24.6 12.0 12.1 17.5 12.2 44.5 121.1 27.7 5.5 8.2 90.9 77.8 11.4 35.4 90.7 42.7 68.4 55.1 52.9 15.5 52.3 41.5 22.4 0.3 42.5 42.0 41.2 0.2 30.1 18.8 24.2 46.0 54.2 82.3 2.3 4.5 6.8 19.7 25.9 17.0 10.9 1.9 31.9 RHOT1 "ARHT1, FLJ11040, MIRO-1, MIRO1" ENSG00000126858 "Ras homolog family member T1" Q8IXI2 17 32142454-32253374 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010687, CAB068223, CAB068224" Supported NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" "CAB068223: AB_2665691, CAB068224: AB_2665692, HPA010687: AB_1079813" "unprognostic (3.28e-2)" "unprognostic (4.02e-3)" "unprognostic (6.85e-2)" "unprognostic (3.53e-1)" "unprognostic (1.57e-2)" "unprognostic (5.49e-2)" "unprognostic (1.59e-3)" "unprognostic (1.59e-2)" "unprognostic (7.02e-3)" "unprognostic (1.29e-1)" "unprognostic (1.38e-1)" "unprognostic (5.05e-1)" "unprognostic (1.01e-2)" "unprognostic (2.97e-2)" "unprognostic (2.58e-1)" "unprognostic (3.90e-1)" "unprognostic (4.08e-2)" 19.1 26.9 19.9 9.6 20.8 19.7 19.5 20.5 29.4 16.6 12.5 19.8 11.4 16.3 15.0 14.9 14.4 11.4 24.8 22.0 18.5 17.6 16.8 17.3 10.9 18.1 17.5 17.7 15.5 38.1 14.2 18.6 19.8 17.1 11.3 50.9 17.3 19.1 28.4 28.5 12.2 16.0 18.7 12.2 17.3 12.3 19.9 19.4 25.0 34.5 11.2 16.6 15.5 24.8 14.1 26.2 21.9 22.8 25.8 28.9 13.2 22.7 18.2 24.2 26.0 13.8 9.0 18.2 22.3 18.7 26.5 24.9 34.3 13.8 29.1 14.4 25.9 21.4 15.8 21.0 35.4 28.1 15.3 15.3 40.7 20.7 23.8 40.5 21.1 36.7 48.1 14.9 21.5 10.6 52.1 23.0 18.0 16.7 12.6 28.6 32.4 32.2 17.5 8.4 20.0 18.1 22.8 14.1 38.4 26.1 31.9 38.1 16.3 17.0 17.5 19.6 16.2 22.0 22.9 19.9 20.5 26.7 28.9 3.0 5.8 5.4 2.1 4.9 2.3 2.1 2.3 2.1 5.3 4.0 1.8 2.3 3.6 3.4 5.2 1.8 1.3 2.8 19.9 20.8 20.5 29.4 22.0 18.5 18.1 17.5 19.8 18.7 19.9 24.8 16.5 28.9 38.8 88.8 17.8 25.9 13.5 14.4 27.9 61.5 21.4 18.0 38.1 14.3 18.7 16.5 70.9 28.4 14.1 12.3 33.2 17.0 19.6 14.5 15.5 17.9 16.9 31.5 97.3 13.1 20.3 19.3 15.3 13.9 27.3 24.8 18.9 18.3 33.7 57.2 89.9 9.3 22.4 46.4 29.1 20.6 30.1 33.2 16.0 76.8 45.1 128.9 29.9 68.3 65.9 13.5 14.4 24.0 11.6 13.7 22.8 21.3 15.1 58.7 26.3 24.8 21.9 63.0 40.3 24.3 53.0 22.7 18.9 24.5 13.9 11.4 RHOV "ARHV, Chp, WRCH2" ENSG00000104140 "Ras homolog family member V" Q96L33 15 40872214-40874234 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 211.8;skin 1: 129.8;vagina: 92.2" "Cell type enhanced" "Detected in many" "Paneth cells: 142.3;Squamous epithelial cells: 375.0;Suprabasal keratinocytes: 283.0;Urothelial cells: 275.1" "Cancer enhanced" "Detected in many" "cervical cancer: 91.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SK-BR-3: 328.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053343 Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA053343: AB_2682122" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (8.29e-3)" "unprognostic (4.34e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.19e-4)" "unprognostic (3.29e-3)" "unprognostic (1.05e-1)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (8.43e-3)" "unprognostic (5.63e-3)" 0.5 0.1 0.9 0.2 0.9 0.2 16.0 1.1 1.8 26.3 0.5 2.8 0.6 0.7 9.5 211.8 2.7 0.5 0.1 1.0 1.1 5.5 0.2 2.3 0.2 2.1 0.8 0.3 16.3 2.2 3.0 3.2 2.4 16.6 2.6 0.0 44.3 2.4 0.2 129.8 0.6 0.1 0.8 0.1 1.2 0.3 1.9 2.6 0.5 0.0 23.3 20.7 92.2 0.9 1.6 9.7 0.1 2.7 0.2 0.0 5.2 0.1 0.8 0.4 0.2 4.0 4.4 0.0 2.4 0.0 0.3 77.9 4.5 0.6 0.2 10.5 12.5 0.5 11.3 0.6 0.0 0.5 0.0 0.3 6.0 0.3 0.1 0.4 0.1 2.3 2.1 0.5 0.0 27.2 0.6 2.3 1.7 19.3 3.7 4.0 0.4 1.8 5.1 34.3 4.0 0.8 8.0 328.9 0.2 0.5 40.9 0.3 0.1 0.0 1.1 0.2 0.3 0.0 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.1 1.8 1.0 1.1 2.1 0.8 2.4 0.8 1.9 0.9 0.6 0.0 3.2 0.3 0.5 84.1 42.5 80.9 19.9 0.0 75.2 48.5 0.9 2.8 103.0 29.5 0.0 60.7 1.9 43.1 13.7 107.5 0.0 18.5 1.9 2.5 22.7 0.0 1.5 56.2 6.0 2.0 7.1 25.5 1.3 0.4 0.0 0.0 4.6 0.0 0.5 54.7 67.1 0.0 13.3 0.0 0.0 0.8 32.0 0.0 3.6 0.0 0.0 0.0 0.3 13.8 142.3 0.7 0.1 89.8 1.0 0.9 26.2 0.0 0.0 0.2 7.3 0.0 0.9 375.0 283.0 42.4 1.9 0.0 66.3 275.1 RHPN2 ENSG00000131941 "Rhophilin Rho GTPase binding protein 2" Q8IUC4 19 32978592-33064888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 61.0;Endometrial ciliated cells: 90.2;Gastric mucus-secreting cells: 94.8;Glandular and luminal cells: 108.8;Muller glia cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 52.4;OE19: 50.7;RPTEC TERT1: 52.9;SK-BR-3: 54.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051749 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "HPA051749: AB_2681589" "unprognostic (1.18e-1)" "unprognostic (1.33e-1)" "unprognostic (1.17e-2)" "unprognostic (3.65e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.08e-3)" "unprognostic (2.32e-1)" "unprognostic (5.07e-3)" "unprognostic (3.01e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.22e-8)" "unprognostic (3.74e-2)" "unprognostic (4.44e-2)" "unprognostic (5.81e-2)" "unprognostic (4.40e-2)" 3.0 0.8 5.5 4.4 5.9 0.0 12.7 5.8 6.6 8.4 7.8 23.6 21.7 5.4 2.4 1.2 15.0 13.6 1.5 5.2 5.8 14.5 19.6 4.1 1.3 6.3 6.9 1.7 12.4 16.9 4.8 8.2 6.1 27.1 19.0 20.2 19.4 2.2 0.3 10.5 17.8 1.8 5.1 0.9 35.2 0.7 7.2 1.9 5.4 0.9 2.6 11.5 1.1 6.4 28.6 52.4 4.9 8.6 1.0 0.1 24.5 6.6 5.0 10.0 10.5 45.9 28.6 0.0 41.1 3.7 8.8 13.5 15.9 5.8 12.4 13.2 9.7 3.2 5.9 17.9 6.6 0.0 4.1 1.2 11.5 8.4 4.7 7.6 1.3 1.2 7.2 0.0 3.0 24.4 0.1 2.9 10.5 50.7 8.4 0.0 6.0 5.6 52.9 14.0 11.0 5.8 11.2 54.5 13.4 13.9 15.2 1.4 0.7 0.1 12.7 3.6 11.2 6.3 4.6 2.1 1.6 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.9 5.8 6.6 5.2 5.8 6.3 6.9 6.1 5.1 7.2 6.4 0.3 22.4 1.1 20.2 3.9 1.3 6.3 6.2 7.4 1.9 30.4 15.4 0.9 17.2 14.7 12.9 12.5 18.2 2.1 61.0 3.9 31.0 0.4 90.2 11.1 1.1 4.8 0.0 1.3 13.1 6.8 6.4 94.8 108.8 1.3 0.2 3.3 13.0 1.9 0.0 1.4 22.2 18.3 3.0 0.0 0.3 2.1 1.6 1.8 4.7 0.0 76.8 0.0 9.5 1.6 33.8 52.6 1.2 6.1 23.5 11.7 19.8 51.9 10.1 0.0 0.6 3.7 0.0 1.4 3.8 1.8 3.4 1.1 0.0 23.3 36.1 RIMKLB "FAM80B, KIAA1238, NAAGS, NAAGS-I" ENSG00000166532 "Ribosomal modification protein rimK like family member B" Q9ULI2 12 8681600-8783095 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 184.2;Endometrial ciliated cells: 191.3;Glandular and luminal cells: 1012.9;Late spermatids: 300.3" "Cancer enhanced" "Detected in many" "testis cancer: 17.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 145.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059552 Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Centriolar satellite" "HPA059552: " "unprognostic (5.29e-3)" "unprognostic (2.26e-2)" "unprognostic (1.89e-5)" "unprognostic (2.40e-2)" "unprognostic (2.30e-1)" "unprognostic (3.35e-2)" "unprognostic (6.56e-2)" "unprognostic (8.52e-2)" "unprognostic (8.67e-3)" "unprognostic (1.76e-1)" "unprognostic (3.25e-1)" "unprognostic (2.15e-1)" "unprognostic (2.01e-1)" "unprognostic (2.16e-2)" "unprognostic (3.02e-1)" "unprognostic (3.74e-1)" "unprognostic (3.99e-1)" 27.6 10.9 20.1 8.0 23.0 21.0 24.1 23.9 18.6 29.5 19.9 30.5 5.4 40.1 15.9 11.1 29.4 14.9 14.4 20.9 23.7 11.8 3.1 19.4 9.1 27.5 24.8 30.1 8.1 22.2 12.8 24.5 22.3 14.1 7.0 19.1 11.8 14.1 13.7 13.0 12.8 27.6 26.7 13.5 11.0 32.4 24.9 13.7 20.0 9.4 7.0 15.4 21.7 21.0 3.7 18.1 43.5 44.9 5.7 5.4 63.0 19.6 8.8 16.1 10.5 1.5 20.6 27.9 16.2 11.7 17.9 6.3 21.5 23.9 17.1 0.5 13.9 13.3 52.4 0.2 6.6 4.1 13.3 11.7 10.4 14.4 24.2 10.1 21.0 22.9 18.0 0.0 9.4 11.8 27.0 2.0 53.2 0.0 1.0 42.0 60.5 0.1 22.8 10.2 1.4 28.2 17.5 24.9 19.4 70.9 6.0 13.4 41.2 15.7 51.0 8.6 6.4 0.2 0.0 145.9 13.3 2.9 10.9 2.1 1.2 0.3 0.8 0.3 1.0 0.7 0.8 1.3 0.5 1.3 1.4 0.5 0.1 1.2 0.5 0.4 0.0 1.0 20.1 23.0 23.9 18.6 20.9 23.7 27.5 24.8 22.3 26.7 24.9 21.0 69.8 28.9 42.9 99.6 13.3 15.2 23.3 16.6 27.9 25.5 10.9 11.4 15.6 7.2 25.7 12.9 0.0 61.0 4.2 1.0 15.6 12.8 184.2 191.3 99.5 38.5 9.0 30.9 33.0 3.0 18.6 27.3 4.1 1012.9 12.0 72.3 22.9 0.0 19.9 13.5 52.7 2.1 16.2 8.8 8.0 300.3 23.3 12.4 33.8 41.2 2.0 34.2 5.2 78.9 9.5 5.8 3.7 30.9 3.8 23.4 6.7 9.1 33.9 3.6 13.1 15.6 29.6 77.1 38.3 17.8 13.4 136.5 11.0 27.7 1.5 21.5 RIMS1 "CORD7, KIAA0340, RAB3IP2, RIM, RIM1" ENSG00000079841 "Regulating synaptic membrane exocytosis 1" Q86UR5 6 71886703-72403143 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "brain: 365.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 653.2;Inhibitory neurons: 572.7;Oligodendrocyte precursor cells: 323.2" "Cancer enhanced" "Detected in single" "prostate cancer: 0.7" "Region enriched" "Detected in many" 16 "cerebellum: 365.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 5.2;EFO-21: 8.8;LHCN-M2: 10.0;RPTEC TERT1: 15.0;SH-SY5Y: 10.7;TIME: 5.4;U-138 MG: 5.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 352.9" HPA076565 Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA076565: " "unprognostic (1.34e-3)" "unprognostic (3.47e-1)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (6.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.73e-2)" "unprognostic (8.57e-2)" "unprognostic (2.85e-1)" "unprognostic (7.76e-4)" "unprognostic (2.42e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-2)" "unprognostic (2.76e-1)" "unprognostic (5.74e-2)" "unprognostic (1.07e-2)" 0.2 1.2 5.5 0.8 14.1 0.0 0.5 365.0 22.5 0.3 0.0 0.3 0.7 0.2 0.0 2.1 0.0 3.9 0.1 16.3 8.4 0.0 0.0 0.2 0.0 0.3 9.0 0.0 0.4 1.6 2.4 0.0 20.8 3.0 0.1 7.4 1.1 0.3 0.2 0.2 0.4 0.7 0.0 0.0 1.4 4.1 5.4 0.0 0.0 0.9 0.0 0.1 0.0 13.2 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.2 1.4 0.0 0.2 0.0 0.0 5.2 8.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.4 1.6 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.5 15.0 0.0 0.4 10.7 0.0 0.0 0.0 0.3 0.7 0.0 5.4 5.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 14.1 365.0 22.5 16.3 8.4 0.3 9.0 20.8 0.0 5.4 13.2 0.2 0.0 0.5 120.2 0.0 0.0 0.2 2.1 0.0 69.1 3.0 3.2 1.4 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 15.2 0.0 0.9 2.5 0.0 0.0 653.2 0.8 0.0 1.8 0.0 0.0 1.3 0.3 3.6 0.0 0.0 62.2 572.7 0.0 2.0 0.0 0.0 10.2 0.3 0.3 3.6 16.9 0.0 109.7 0.0 323.2 76.5 0.5 0.0 1.5 0.0 1.0 0.0 0.4 3.6 9.9 0.0 1.3 2.7 21.3 13.6 0.0 0.1 0.0 0.1 0.3 0.0 0.5 RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500696-104256094 "Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 50.6;brain: 48.2;retina: 102.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 383.6;Cone photoreceptor cells: 706.8;Excitatory neurons: 1589.3;Inhibitory neurons: 1234.9;Oligodendrocyte precursor cells: 577.0;Rod photoreceptor cells: 1088.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 9.2;RT4: 7.3;SCLC-21H: 16.5;SuSa: 8.8;U-2 OS: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: AB_2685678" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (4.47e-2)" "unprognostic (5.51e-2)" "unprognostic (2.82e-1)" "unprognostic (7.09e-3)" "unprognostic (2.02e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (8.01e-3)" "unprognostic (1.40e-2)" "unprognostic (6.34e-2)" "unprognostic (1.67e-5)" "unprognostic (8.12e-4)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" 0.2 50.6 22.4 0.2 27.1 0.4 0.7 35.5 48.2 7.5 0.0 0.1 0.4 0.6 0.9 0.3 5.9 0.9 0.1 18.4 16.4 0.3 0.1 0.1 0.3 5.5 9.7 2.0 0.7 0.0 15.0 0.4 6.4 1.7 0.1 102.3 0.8 1.0 0.2 0.3 0.5 1.3 3.5 0.1 0.6 2.8 16.7 0.8 1.3 0.1 0.2 1.7 2.4 29.4 4.6 0.0 4.8 0.0 0.0 0.1 0.0 0.4 0.3 1.0 1.3 0.1 0.3 9.2 0.1 0.1 1.4 0.3 1.9 0.8 2.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 1.0 1.5 0.0 1.2 0.0 0.5 0.0 0.4 0.9 0.0 4.0 0.0 0.5 0.0 0.0 0.0 0.0 7.3 16.5 3.3 0.0 0.1 0.7 8.8 0.4 0.2 0.0 0.0 6.5 0.1 0.1 1.2 0.0 0.1 0.4 0.3 0.3 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 22.4 27.1 35.5 48.2 18.4 16.4 5.5 9.7 6.4 3.5 16.7 29.4 0.4 28.9 22.5 38.5 0.2 0.3 1.8 2.8 1.8 383.6 0.7 0.6 0.9 1.5 16.9 0.0 706.8 0.5 0.1 0.2 1.9 0.1 34.2 2.1 0.4 4.9 8.4 0.0 1589.3 0.0 0.3 3.7 0.0 3.7 16.4 18.0 0.7 0.3 0.3 67.3 1234.9 0.9 0.0 0.6 0.8 20.1 72.1 2.5 1.8 63.7 0.6 86.6 1.0 577.0 27.0 0.3 1.2 29.3 0.3 4.1 2.0 0.2 10.6 1088.7 0.0 0.8 1.0 34.8 15.7 0.8 0.4 0.1 2.1 0.1 1.5 1.1 RIN1 ENSG00000174791 "Ras and Rab interactor 1" Q13671 11 66330241-66336840 "Predicted intracellular proteins, RAS pathway related proteins" Endocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 25.7;Basal squamous epithelial cells: 23.3;Squamous epithelial cells: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 9.7" "Lineage enriched" "Detected in many" 6 "monocytes: 9.7" "Cell line enhanced" "Detected in many" "hTCEpi: 44.3;U-2197: 40.7" "Low region specificity" "Detected in many" HPA035491 Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear membrane" Nucleoplasm "HPA035491: AB_10601608" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (4.69e-2)" "prognostic favorable (2.21e-4)" "unprognostic (1.11e-2)" "unprognostic (2.57e-1)" "unprognostic (6.82e-3)" "unprognostic (3.84e-2)" "unprognostic (1.11e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (9.34e-7)" "unprognostic (2.42e-2)" "unprognostic (1.14e-1)" "unprognostic (7.82e-3)" "unprognostic (2.46e-1)" 4.8 4.3 3.7 2.3 4.9 1.1 4.4 3.3 5.7 8.3 1.5 5.2 2.7 4.4 0.2 20.4 5.6 1.4 3.4 6.3 1.6 4.3 1.3 4.9 0.5 1.0 1.2 3.7 5.2 0.4 7.2 1.4 1.1 7.1 1.0 0.2 5.1 0.8 7.5 26.6 4.3 0.6 0.8 6.1 6.8 3.7 2.0 0.5 2.4 0.5 0.4 5.4 11.3 2.6 2.3 5.7 2.3 5.3 2.8 14.5 1.2 13.7 18.0 14.4 6.8 3.3 9.3 0.5 5.0 13.6 5.2 12.9 0.0 24.3 1.8 1.1 0.0 0.8 4.4 4.1 5.5 0.1 4.2 15.9 44.3 12.4 8.0 17.1 2.8 0.6 0.3 0.1 6.1 0.5 0.3 11.0 0.6 3.9 12.6 0.1 5.4 0.1 3.9 3.0 10.9 2.3 3.2 2.5 20.5 0.6 1.8 1.3 6.5 18.7 7.9 40.7 3.3 0.3 0.9 0.0 26.9 3.5 6.3 0.1 2.7 0.0 0.2 4.7 0.6 0.1 0.4 0.2 1.7 0.0 0.5 0.2 0.0 0.1 9.7 0.0 0.1 1.8 3.7 4.9 3.3 5.7 6.3 1.6 1.0 1.2 1.1 0.8 2.0 2.6 3.9 0.0 0.5 1.3 0.8 13.4 9.3 25.7 23.3 3.8 3.5 4.3 0.8 4.3 4.8 0.0 0.0 0.8 0.5 9.6 0.0 4.1 0.5 2.4 5.1 5.3 3.0 0.0 6.0 6.9 4.8 5.6 5.6 1.8 4.5 0.1 7.9 0.2 4.7 0.0 2.3 4.5 2.0 8.7 6.5 2.0 4.4 6.4 1.8 1.0 8.1 0.7 1.0 0.5 0.5 8.9 7.8 1.9 1.4 4.0 9.1 0.1 3.4 1.2 0.0 4.2 3.4 1.2 0.9 18.6 15.2 0.3 2.2 1.6 9.2 5.8 RIN3 FLJ22439 ENSG00000100599 "Ras and Rab interactor 3" Q8TB24 14 92513781-92688994 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 46.3" "Cell type enhanced" "Detected in many" "Kupffer cells: 125.1;Macrophages: 78.7;Microglial cells: 100.2;monocytes: 109.8;NK-cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 35.7;classical monocyte: 43.4;eosinophil: 54.1;intermediate monocyte: 40.4;myeloid DC: 41.6;neutrophil: 40.2;NK-cell: 21.5;non-classical monocyte: 50.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "HMC-1: 108.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA079218 Approved NA NA 7400 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA079218: " "unprognostic (1.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.93e-1)" "unprognostic (1.87e-1)" "unprognostic (7.18e-2)" "unprognostic (6.40e-2)" "unprognostic (2.44e-1)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (3.07e-3)" "unprognostic (5.69e-3)" "unprognostic (5.13e-2)" "unprognostic (5.90e-3)" "unprognostic (2.88e-2)" "unprognostic (6.95e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" 10.5 13.6 4.3 9.6 3.6 46.3 8.1 4.1 5.3 7.3 2.8 19.1 6.6 15.4 1.6 6.7 8.7 8.1 8.6 4.4 6.6 4.5 12.4 16.3 6.1 9.6 5.9 6.7 2.2 5.4 2.7 6.4 7.0 7.0 4.8 0.2 5.1 5.1 3.2 5.3 9.7 10.2 7.5 22.8 6.4 5.2 9.1 10.9 5.0 2.9 5.3 10.6 8.6 8.6 10.3 19.8 4.4 1.7 1.7 14.3 15.0 12.9 14.0 12.0 8.0 7.5 17.5 0.0 12.1 19.1 8.2 22.0 3.1 0.1 5.5 10.6 3.9 21.4 1.5 8.1 8.7 6.9 108.1 8.1 7.7 11.5 4.8 4.7 7.1 2.6 3.1 0.5 5.0 6.5 3.3 16.3 2.7 1.1 6.0 2.7 2.1 0.2 4.9 6.9 1.0 0.0 6.2 2.1 9.5 4.3 0.1 2.5 12.5 13.8 10.8 20.1 10.9 3.1 0.0 0.2 13.5 0.3 18.1 35.7 43.4 54.1 10.1 40.4 3.4 7.8 4.7 4.9 41.6 8.5 6.8 7.7 40.2 21.5 50.8 1.8 3.0 24.5 4.3 3.6 4.1 5.3 4.4 6.6 9.6 5.9 7.0 7.5 9.1 8.6 19.2 0.0 8.9 18.3 28.2 3.8 2.0 3.4 0.6 2.2 3.7 5.5 4.7 1.5 2.2 0.0 0.0 5.1 44.0 9.2 0.0 1.6 10.2 2.2 3.5 15.4 0.0 12.6 6.9 1.4 3.1 4.2 1.1 2.6 51.4 5.4 8.2 14.9 49.3 0.0 5.2 7.3 4.1 125.1 50.8 6.6 5.3 78.7 12.4 100.2 109.8 0.0 114.4 20.6 0.9 10.1 3.8 18.8 9.7 3.8 9.5 6.2 2.5 0.3 13.1 10.1 4.6 19.1 4.0 1.1 2.7 12.7 32.5 1.9 8.9 3.6 RMI1 "BLAP75, C9orf76, FLJ12888" ENSG00000178966 "RecQ mediated genome instability 1" Q9H9A7 9 83980798-84004074 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 70.0;Late spermatids: 62.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021661 Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" "HPA021661: " "unprognostic (9.59e-2)" "unprognostic (7.96e-2)" "unprognostic (6.72e-3)" "unprognostic (3.03e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.65e-1)" "unprognostic (3.39e-3)" "unprognostic (1.32e-1)" "unprognostic (5.55e-2)" "unprognostic (2.26e-1)" "unprognostic (1.53e-1)" "unprognostic (3.68e-3)" "unprognostic (3.42e-1)" "unprognostic (2.42e-1)" "unprognostic (9.24e-2)" 2.5 8.3 2.9 6.0 3.2 3.9 4.5 4.6 3.4 3.2 6.0 6.6 6.2 3.5 5.6 4.9 5.8 2.8 3.4 2.4 5.8 4.4 5.8 3.3 10.2 3.3 3.3 4.4 5.8 7.7 3.7 3.6 3.5 4.8 7.4 7.0 6.0 3.1 3.7 5.1 6.8 3.3 3.2 6.4 6.2 8.9 3.8 10.2 6.0 3.9 9.6 3.6 2.4 3.8 25.2 14.9 33.6 12.4 5.5 7.7 33.9 24.1 13.6 20.7 19.4 7.5 17.0 55.4 8.5 12.4 21.7 36.9 22.0 12.3 25.3 29.2 6.1 23.0 12.1 11.8 7.7 42.6 23.1 7.4 7.8 17.6 12.6 6.7 11.1 28.2 16.7 26.3 23.2 18.1 54.4 17.4 31.3 31.6 15.7 47.8 33.9 21.0 10.8 10.4 30.4 19.3 21.3 18.6 9.8 15.4 19.4 20.8 6.6 22.9 14.7 23.2 20.1 11.6 25.6 20.2 14.6 19.7 26.4 14.2 4.5 8.8 1.8 5.5 2.2 2.8 2.1 1.9 7.2 2.6 2.2 2.5 7.8 2.8 6.5 2.2 3.0 2.6 2.9 3.2 4.6 3.4 2.4 5.8 3.3 3.3 3.5 3.2 3.8 3.8 5.4 9.6 5.1 10.1 5.9 2.7 3.2 4.3 4.0 4.1 4.3 3.3 8.5 2.8 9.0 1.8 4.2 7.9 2.1 6.1 5.9 5.5 70.0 13.9 6.5 3.8 6.7 24.4 7.1 3.0 16.2 3.3 8.2 10.2 4.5 9.0 5.0 13.3 8.1 10.1 11.2 9.8 0.0 10.7 4.3 62.1 2.1 7.4 12.4 8.4 8.5 7.7 5.2 26.2 12.6 2.7 5.6 2.2 7.8 4.2 8.9 4.9 11.1 5.2 0.0 3.3 3.4 34.0 22.6 6.9 4.8 4.2 4.4 7.7 10.1 2.4 RMND5B "FLJ22318, GID2, GID2B" ENSG00000145916 "Required for meiotic nuclear division 5 homolog B" Q96G75 5 178130996-178150568 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 186.6;Late spermatids: 415.4;Spermatocytes: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 130.3;MCF7: 185.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047778 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA047778: AB_2680153" "unprognostic (2.08e-1)" "unprognostic (6.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.35e-2)" "unprognostic (4.38e-2)" "unprognostic (9.81e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.48e-1)" "prognostic favorable (7.66e-4)" "unprognostic (1.60e-1)" "prognostic favorable (7.22e-8)" "unprognostic (1.77e-2)" "unprognostic (1.41e-1)" "unprognostic (6.43e-2)" "unprognostic (5.78e-2)" 18.9 23.4 19.8 11.2 19.7 13.2 18.8 19.2 20.3 24.0 19.4 24.5 13.2 22.7 12.2 69.8 19.2 9.6 28.1 19.7 18.7 22.4 27.2 17.4 18.0 22.3 19.4 17.1 25.4 23.5 20.7 16.4 19.1 19.0 11.4 10.5 24.2 15.9 45.6 29.6 17.3 15.9 19.6 19.2 23.2 81.6 21.2 23.7 20.5 32.4 23.0 22.1 28.2 20.9 21.3 37.5 21.4 53.5 27.4 2.8 71.3 16.9 18.2 25.1 29.2 42.1 30.2 44.6 32.9 11.9 27.6 27.6 21.5 36.7 8.8 130.3 28.7 46.8 39.1 22.8 29.0 21.9 16.3 5.9 27.1 17.3 27.3 14.0 25.5 14.7 40.1 28.8 8.1 185.2 15.5 12.5 29.5 25.9 20.4 19.7 15.8 31.6 21.1 32.4 22.5 32.2 22.8 73.0 40.3 17.3 56.9 29.5 17.7 13.9 21.9 12.8 21.3 42.4 43.4 37.0 18.2 21.2 19.6 21.8 16.5 42.5 6.5 20.1 2.8 18.3 13.0 7.3 8.8 24.9 20.4 11.3 11.4 4.2 27.2 13.7 22.4 12.4 19.8 19.7 19.2 20.3 19.7 18.7 22.3 19.4 19.1 19.6 21.2 20.9 13.5 12.8 6.9 7.8 20.5 9.6 20.6 15.3 14.2 48.6 19.3 16.1 22.2 27.1 12.2 31.3 52.1 31.7 8.0 17.6 23.5 21.0 186.6 7.8 10.2 13.3 9.0 28.0 15.4 19.1 29.8 16.7 23.0 10.5 5.1 16.4 15.0 14.0 21.7 48.8 16.6 15.0 28.5 15.0 9.6 415.4 28.9 10.5 7.2 10.3 22.7 30.9 14.4 8.5 14.1 19.1 13.3 25.2 14.8 20.6 26.1 21.6 7.3 61.4 13.1 17.5 16.3 133.0 35.7 28.9 13.4 44.5 10.9 18.5 17.9 20.0 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 RNASE7 RAE1 ENSG00000165799 "Ribonuclease A family member 7" Q9H1E1 14 21042316-21044234 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 74.9;lymphoid tissue: 24.1;skin 1: 27.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 30.2;Cholangiocytes: 8.6;Prostatic glandular cells: 7.3;Urothelial cells: 27.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 24.7;hTCEpi: 10.3;hTERT-HME1: 53.3" "HPA005690, CAB062560, CAB068225" Enhanced "Secreted in other tissues" NA NA 280000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "CAB062560: AB_2665595, CAB068225: AB_2665594, HPA005690: AB_1079819" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (8.27e-2)" "unprognostic (7.80e-2)" "unprognostic (8.73e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.17e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "unprognostic (3.24e-1)" "unprognostic (3.42e-1)" 0.1 0.1 0.0 0.0 0.0 0.0 3.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 74.9 0.0 6.6 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.3 0.5 0.0 4.7 0.5 0.3 27.9 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.0 0.0 0.0 24.1 0.2 9.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.1 53.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 30.2 1.5 0.0 0.0 0.1 2.4 0.5 8.6 0.4 0.0 0.0 1.5 0.0 0.1 0.0 4.5 0.9 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.0 0.0 0.3 5.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 7.3 0.0 0.0 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 5.3 0.3 0.0 0.2 27.2 RNASEH2A "AGS4, RNASEHI, RNHIA, RNHL" ENSG00000104889 "Ribonuclease H2 subunit A" O75792 19 12806584-12813640 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 62.3;Extravillous trophoblasts: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042692 Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA042692: AB_10793981" "unprognostic (6.74e-2)" "prognostic favorable (1.18e-4)" "prognostic favorable (6.18e-4)" "unprognostic (2.24e-1)" "unprognostic (2.62e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (8.48e-2)" "unprognostic (9.33e-2)" "prognostic favorable (1.22e-4)" "unprognostic (3.80e-3)" "unprognostic (8.71e-2)" "prognostic unfavorable (6.29e-6)" "unprognostic (3.40e-3)" "unprognostic (4.35e-2)" "unprognostic (5.35e-2)" "unprognostic (8.60e-2)" 8.9 6.8 7.0 11.8 7.2 28.0 9.0 10.4 9.1 10.8 6.2 10.5 10.3 8.5 4.9 18.3 10.6 4.9 7.6 7.2 6.1 7.4 6.9 7.3 17.1 7.3 6.5 8.9 9.2 5.3 5.4 10.4 7.4 6.0 10.7 8.4 8.6 5.0 8.9 13.9 10.0 8.2 6.0 14.5 9.4 19.8 6.8 24.4 7.5 6.6 18.7 8.2 10.8 9.5 130.0 103.8 94.8 75.7 12.3 23.4 76.2 68.4 40.0 126.3 136.0 76.2 58.7 126.9 106.2 36.6 59.6 79.4 82.6 89.2 83.5 82.7 118.1 67.7 112.9 89.9 7.1 70.6 60.5 10.4 19.7 110.7 43.9 21.4 47.3 114.8 91.2 46.8 82.0 251.4 132.8 83.0 56.4 79.1 167.4 146.1 102.0 113.7 39.6 63.8 119.8 76.7 67.0 39.8 46.7 39.8 76.1 78.4 29.3 129.2 55.7 197.0 126.1 97.6 130.3 108.5 77.4 129.4 105.5 9.4 19.1 17.2 23.9 27.6 23.3 36.8 19.6 22.5 19.0 36.3 15.9 19.6 4.4 44.8 27.7 21.0 25.8 19.1 7.0 7.2 10.4 9.1 7.2 6.1 7.3 6.5 7.4 6.0 6.8 9.5 5.3 0.0 2.6 1.3 15.3 14.0 15.7 22.9 6.8 16.2 2.8 11.7 2.7 12.8 7.6 0.0 4.2 62.3 9.1 11.3 0.0 5.4 16.1 0.8 1.6 9.0 8.4 38.7 2.2 6.0 117.4 10.3 10.7 1.1 3.8 2.5 11.7 4.4 48.9 8.4 3.0 13.9 22.4 9.1 13.2 18.8 8.4 9.3 12.4 1.9 8.5 10.4 14.4 1.0 2.4 2.1 6.8 4.9 33.0 5.3 6.2 1.0 9.5 13.9 6.6 15.6 9.8 51.2 44.9 23.8 13.2 22.7 10.2 0.8 24.8 16.1 RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30970984-30999911 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 63.3" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA021576: AB_1856331, HPA052404: AB_2681817" "unprognostic (1.13e-1)" "unprognostic (1.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-2)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (6.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (4.47e-1)" 20.9 12.9 11.1 13.5 12.5 11.6 18.6 11.2 14.2 16.0 15.1 17.5 13.6 13.3 16.5 22.4 15.7 9.6 8.5 10.4 11.3 21.6 8.6 15.5 13.9 13.9 13.2 12.6 13.5 16.8 5.6 18.1 12.4 14.0 18.0 2.3 15.2 15.2 7.4 26.2 13.9 13.7 12.8 25.8 11.9 5.1 16.4 7.9 15.8 10.1 12.6 14.8 17.3 13.8 12.7 25.6 1.5 25.4 34.0 28.5 22.7 9.7 14.9 9.4 8.4 0.0 9.4 11.5 14.8 19.0 17.0 17.0 13.2 12.1 7.8 10.0 5.6 4.8 8.1 0.0 24.3 12.8 10.7 27.7 63.3 10.1 33.5 16.1 15.8 0.0 0.0 34.9 15.6 17.0 0.1 13.5 10.5 25.7 14.4 27.9 0.0 39.2 13.6 18.2 9.8 0.5 14.9 5.9 14.9 16.6 39.4 20.2 13.3 0.0 3.5 15.6 11.5 0.4 1.3 7.3 16.5 22.1 13.3 25.3 61.6 31.3 12.8 57.3 7.2 28.4 6.8 6.8 46.4 28.4 3.7 6.2 54.0 13.9 70.2 17.1 10.1 29.2 11.1 12.5 11.2 14.2 10.4 11.3 13.9 13.2 12.4 12.8 16.4 13.8 14.1 3.2 5.9 7.8 14.1 9.3 13.4 16.8 22.2 0.1 13.1 15.0 4.0 7.2 7.8 11.0 0.0 47.5 10.5 23.4 29.4 9.9 0.4 14.5 12.8 13.2 4.9 11.2 0.8 18.6 37.1 13.2 5.6 12.4 1.3 14.1 25.4 2.7 51.1 0.0 1.0 12.0 8.2 73.9 8.4 1.6 16.8 35.5 16.0 26.2 45.3 3.9 19.6 9.0 0.7 11.9 13.1 15.4 9.0 22.2 27.5 49.3 10.4 0.6 26.3 8.2 14.2 0.7 4.0 24.1 14.6 43.6 7.5 10.6 14.6 11.2 RNF141 "ZFP26, ZNF230" ENSG00000110315 "Ring finger protein 141" Q8WVD5 11 10511673-10541230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 1045.8;Late spermatids: 666.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 176.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018133 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" Microtubules Nucleoplasm "HPA018133: AB_1859142" "unprognostic (7.41e-2)" "unprognostic (1.16e-1)" "unprognostic (7.88e-3)" "unprognostic (8.42e-2)" "unprognostic (2.12e-1)" "unprognostic (3.09e-2)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (1.44e-1)" "unprognostic (5.50e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (4.57e-2)" "prognostic favorable (2.60e-4)" "unprognostic (6.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.71e-2)" "unprognostic (1.61e-2)" 24.0 28.3 41.2 26.8 61.9 19.8 26.9 56.4 61.6 17.6 22.9 17.3 21.7 13.7 19.7 56.3 16.3 14.5 22.7 34.0 51.6 23.5 21.8 21.7 17.9 61.3 52.7 10.9 14.5 30.6 10.0 14.9 63.4 22.6 16.8 18.6 38.3 14.2 43.4 42.9 30.0 13.3 52.1 27.7 21.6 82.7 48.4 18.8 22.9 35.7 25.6 21.0 22.9 79.7 48.3 24.6 34.5 21.1 51.7 50.2 24.6 32.2 26.1 12.6 15.1 38.3 176.3 19.9 28.3 25.0 22.3 34.8 15.3 38.4 19.0 21.7 20.1 13.3 15.8 19.9 20.0 22.2 15.2 33.0 44.0 6.7 41.1 45.8 33.9 25.2 38.4 18.7 31.6 20.6 21.2 8.3 17.5 32.3 14.0 27.3 14.8 22.9 20.4 52.9 11.0 21.5 31.1 36.8 20.6 29.5 23.4 11.3 36.3 30.1 18.5 24.6 10.4 8.2 16.5 22.7 37.7 31.3 37.3 34.2 52.3 92.7 8.3 106.8 13.9 67.6 9.6 8.1 28.9 69.9 10.5 7.3 152.4 9.2 103.9 26.6 12.8 33.9 41.2 61.9 56.4 61.6 34.0 51.6 61.3 52.7 63.4 52.1 48.4 79.7 15.1 19.2 49.2 14.4 39.4 40.8 39.7 47.7 37.0 20.3 31.7 22.0 46.7 18.6 36.9 20.2 12.5 14.4 18.8 16.6 41.1 21.2 1045.8 18.5 14.0 18.4 21.0 15.4 10.7 24.7 15.1 15.9 16.8 23.0 13.3 18.8 21.0 28.0 41.6 37.0 11.8 28.2 16.2 107.4 10.5 666.5 19.6 52.6 19.6 4.7 41.7 27.8 4.1 12.1 67.9 41.6 11.2 19.5 15.2 53.3 58.8 33.5 48.0 11.0 6.6 19.1 18.6 83.4 39.4 49.1 40.1 17.9 11.7 23.3 21.1 74.8 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: AB_2680894" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favorable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favorable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 75.0 110.6 141.9 53.0 146.7 69.0 73.1 146.4 179.9 93.2 138.6 111.5 66.6 94.9 76.4 122.1 84.3 45.3 131.8 141.5 146.4 106.7 184.2 77.5 64.5 146.3 145.4 87.4 115.1 105.8 96.8 50.7 146.3 95.0 65.7 98.1 92.5 70.5 152.9 127.8 100.5 52.8 142.4 113.8 111.8 110.6 150.3 98.1 93.4 94.2 71.6 106.7 90.4 153.3 102.6 143.1 61.1 73.7 132.8 68.7 92.7 63.4 76.1 119.7 93.4 96.2 43.3 71.5 120.3 93.5 63.9 147.5 103.2 114.8 86.1 74.5 166.1 121.9 164.4 94.9 100.6 59.0 245.0 79.6 176.5 129.8 116.2 74.6 77.2 101.0 49.9 237.5 96.2 66.3 92.8 70.6 75.4 102.0 86.8 62.8 61.9 91.5 137.3 77.4 49.2 61.1 56.0 92.9 81.9 83.1 87.3 55.9 49.5 76.6 48.3 66.8 119.3 79.5 88.0 23.7 98.4 80.6 77.9 108.4 88.8 236.9 195.3 94.0 153.4 100.4 148.0 195.7 73.9 98.7 103.2 152.2 219.8 118.8 117.7 75.9 153.0 177.0 141.9 146.7 146.4 179.9 141.5 146.4 146.3 145.4 146.3 142.4 150.3 153.3 36.9 0.0 3.9 12.4 54.3 68.6 44.4 65.8 51.8 43.2 56.6 44.7 15.8 77.2 38.9 49.7 20.9 120.1 64.7 65.2 56.7 78.5 59.6 29.8 25.1 36.4 31.8 60.6 11.3 66.7 139.7 36.3 36.2 32.2 14.0 26.3 45.7 95.1 58.4 18.5 11.2 45.7 65.1 41.3 43.6 86.5 48.7 36.1 39.2 6.5 53.1 46.9 114.4 10.1 17.9 60.7 44.9 53.8 59.1 32.6 108.2 64.0 31.1 32.3 39.5 28.4 35.1 127.1 106.7 61.4 83.3 125.2 82.5 37.2 59.6 48.0 RNF185 FLJ38628 ENSG00000138942 "Ring finger protein 185" Q96GF1 22 31160182-31207019 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.33e-1)" "unprognostic (3.65e-3)" "unprognostic (4.76e-3)" "unprognostic (2.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.97e-1)" "unprognostic (2.56e-1)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "prognostic favorable (4.82e-5)" "unprognostic (3.04e-1)" "unprognostic (1.63e-1)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" 19.8 18.7 21.5 14.4 22.5 10.1 22.8 21.7 25.1 22.3 22.5 23.4 20.5 22.5 25.1 25.9 23.0 16.4 21.1 22.5 22.1 36.2 48.4 19.0 16.2 21.7 22.0 26.1 19.2 48.8 15.8 21.0 22.0 38.2 22.2 16.5 30.2 28.7 23.4 29.9 21.9 25.6 21.9 16.6 21.7 10.8 23.2 21.0 52.0 25.5 21.3 24.2 23.0 23.6 23.7 13.8 26.1 29.9 51.8 34.5 24.9 27.7 53.3 37.2 50.2 15.6 11.1 22.5 15.2 49.3 32.8 14.6 25.3 28.6 38.1 22.6 27.5 9.8 13.2 19.1 72.5 24.1 14.6 37.1 100.8 26.2 60.2 34.0 31.7 23.5 11.7 26.2 45.2 16.8 20.8 13.5 11.7 48.8 15.2 21.1 26.1 26.5 27.0 20.4 11.6 23.4 20.2 26.5 41.0 26.7 18.4 15.8 22.2 26.1 18.7 30.9 13.6 36.2 31.6 28.4 34.5 15.1 21.4 16.9 15.7 9.0 12.2 15.8 13.6 10.0 12.4 13.8 13.3 8.2 12.5 11.5 22.3 16.9 13.7 4.9 14.6 14.8 21.5 22.5 21.7 25.1 22.5 22.1 21.7 22.0 22.0 21.9 23.2 23.6 9.3 22.4 12.6 10.7 8.8 9.1 10.3 10.0 9.6 11.0 14.2 10.8 5.5 20.0 11.5 18.4 8.4 13.0 11.3 16.4 21.5 15.1 19.0 8.9 8.2 8.5 16.8 5.0 14.0 14.9 23.2 10.9 8.2 10.3 5.7 8.4 23.2 28.9 14.2 8.4 17.3 15.8 14.2 8.8 7.5 18.3 7.5 10.5 8.8 10.3 10.7 11.9 7.2 13.6 22.5 15.5 12.7 15.8 6.8 14.5 17.7 22.9 12.4 7.8 6.6 9.5 9.3 7.4 9.8 10.6 10.7 37.2 7.2 6.0 7.8 9.8 RNF187 "RACO-1, RACO1" ENSG00000168159 "Ring finger protein 187" Q5TA31 1 228487382-228496188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/70: 189.0" "Low region specificity" "Detected in all" HPA030098 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA030098: AB_10602923" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (2.83e-4)" "unprognostic (4.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.93e-2)" "unprognostic (3.46e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (5.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.92e-3)" "unprognostic (1.59e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" 26.8 66.6 16.2 7.5 16.2 11.3 25.8 14.8 24.3 40.5 3.4 28.1 8.6 31.8 4.3 59.1 28.7 5.6 35.4 15.9 16.9 40.7 52.0 23.6 7.3 19.4 15.2 39.3 34.5 22.5 47.7 5.5 18.4 33.5 3.7 9.0 39.7 8.2 64.2 45.0 22.5 5.6 15.6 37.0 27.6 20.8 18.5 8.5 36.1 19.8 6.1 29.9 41.2 19.8 26.7 23.1 14.8 28.9 16.8 12.5 26.6 21.5 17.3 15.6 12.7 12.8 19.2 65.9 43.1 28.9 11.4 20.9 19.1 22.1 5.8 25.9 28.5 20.8 13.2 12.6 46.1 22.1 34.4 20.4 44.7 11.6 15.8 18.3 14.0 52.6 35.6 115.2 12.4 17.7 35.2 20.8 30.7 19.1 24.0 27.8 12.5 61.5 11.4 17.2 29.9 30.0 21.9 44.1 62.3 4.3 34.6 50.2 27.8 18.3 16.9 19.6 19.3 189.0 56.7 36.4 46.7 22.7 28.7 0.0 0.5 3.6 0.6 1.0 0.7 0.5 0.7 1.0 0.6 1.0 0.6 0.7 0.1 0.4 1.4 0.7 0.6 0.3 16.2 16.2 14.8 24.3 15.9 16.9 19.4 15.2 18.4 15.6 18.5 19.8 54.0 25.6 15.5 8.1 47.2 36.2 42.9 10.6 38.7 85.2 59.5 58.5 70.8 65.8 14.2 40.5 18.8 19.7 52.2 39.8 113.5 15.2 0.8 35.5 47.2 32.1 40.0 118.4 16.6 24.5 27.1 54.4 34.7 32.0 44.5 45.0 41.7 67.4 27.4 55.5 17.2 36.6 2.0 40.1 30.5 4.2 24.5 35.8 39.2 12.2 29.7 145.3 62.8 7.1 12.6 21.4 23.4 25.9 35.4 44.0 32.9 126.4 10.3 47.7 19.7 52.2 38.4 4.2 21.5 57.0 55.3 17.6 54.6 217.5 38.6 31.7 RNF225 ENSG00000269855 "Ring finger protein 225" M0QZC1 19 58396090-58397079 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 2.9;esophagus: 6.6;skin 1: 4.6;vagina: 2.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "unprognostic (3.07e-1)" "unprognostic (6.94e-2)" "unprognostic (3.68e-3)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "unprognostic (1.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.75e-3)" "unprognostic (1.40e-1)" "unprognostic (3.42e-1)" "unprognostic (9.18e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 2.9 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.1 2.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 RNF227 LINC02581 ENSG00000179859 "Ring finger protein 227" A6NIN4 17 7913339-7916289 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 5 "skin 1: 64.3" "Cell type enhanced" "Detected in some" "Adipocytes: 3.9;Breast glandular cells: 3.9;Breast myoepithelial cells: 4.1;Endometrial ciliated cells: 5.0;Endometrial stromal cells: 8.9;Glandular and luminal cells: 5.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 17.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 17.5" "Cell line enhanced" "Detected in many" "SiHa: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "unprognostic (8.85e-3)" "prognostic favorable (8.89e-5)" "unprognostic (1.50e-2)" "unprognostic (4.88e-2)" "unprognostic (3.72e-3)" "unprognostic (1.44e-2)" "unprognostic (2.02e-5)" "unprognostic (9.48e-2)" "unprognostic (9.22e-3)" "unprognostic (2.94e-2)" "unprognostic (3.11e-2)" "unprognostic (3.31e-2)" "unprognostic (7.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.18e-1)" "unprognostic (3.30e-2)" "unprognostic (1.80e-2)" 5.8 3.2 5.3 1.9 5.5 1.7 4.8 7.0 6.4 3.4 4.1 2.9 3.5 6.2 4.6 4.5 5.0 1.9 1.8 5.5 5.5 2.6 1.1 3.5 2.5 4.9 5.0 5.1 3.5 4.7 3.9 2.2 4.7 2.9 2.0 11.9 3.1 2.1 1.4 64.3 2.9 2.6 4.7 3.0 2.5 3.3 5.4 2.3 1.7 1.6 2.7 2.2 4.1 5.2 7.0 1.4 2.6 2.6 2.0 1.8 2.2 6.5 2.6 1.8 2.0 4.1 2.0 1.3 3.8 2.6 1.6 5.0 1.5 3.3 3.2 0.8 1.7 1.8 5.1 0.3 3.8 3.8 3.3 2.3 9.4 2.9 3.1 0.9 0.4 6.9 2.1 1.3 4.1 0.8 5.1 4.8 1.8 2.1 1.0 2.4 6.4 1.5 2.6 0.9 1.1 3.6 14.1 0.6 2.8 0.8 1.7 2.8 0.4 0.1 3.6 3.1 1.3 1.8 0.6 1.9 3.8 4.2 4.9 17.5 1.3 0.4 1.7 0.9 2.2 1.9 1.9 2.2 2.0 1.3 3.5 2.4 0.8 2.7 0.8 1.3 1.5 1.5 5.3 5.5 7.0 6.4 5.5 5.5 4.9 5.0 4.7 4.7 5.4 5.2 3.9 3.2 2.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 3.9 4.1 0.0 0.0 0.0 0.0 0.0 1.3 2.7 0.0 1.9 1.0 0.0 5.0 8.9 1.1 0.0 0.0 0.0 0.2 0.5 1.9 0.0 5.5 0.0 2.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.8 2.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.7 0.7 2.2 0.0 0.0 RNF43 "DKFZp781H0392, FLJ20315, URCC" ENSG00000108375 "Ring finger protein 43" Q68DV7 17 58353676-58417595 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.7;Intestinal goblet cells: 41.6;Undifferentiated cells: 63.6" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 41.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 17.0;CACO-2: 24.7;Hep G2: 49.4;OE19: 54.7" HPA008079 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA008079: AB_1856371" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (7.46e-2)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.33e-2)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.69e-2)" "unprognostic (3.79e-1)" "prognostic favorable (6.04e-9)" "unprognostic (3.61e-3)" "unprognostic (2.56e-1)" "unprognostic (3.58e-1)" "unprognostic (1.04e-2)" 0.2 10.9 1.7 2.0 3.1 0.7 5.5 9.6 2.7 2.6 1.5 13.4 22.7 1.7 4.4 10.4 4.8 2.7 2.7 2.0 1.3 6.1 9.1 3.6 0.4 1.8 3.4 0.9 8.2 5.2 4.3 4.8 1.9 9.4 19.3 1.2 9.3 4.8 0.3 11.3 16.9 0.6 1.4 0.5 5.8 3.4 2.3 3.7 1.9 0.0 1.5 2.1 5.2 1.4 1.1 17.0 2.7 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 24.7 8.2 0.0 8.5 0.0 1.9 4.6 0.6 6.8 0.0 8.6 11.3 1.9 0.8 49.4 0.0 0.2 0.1 0.0 13.4 0.0 2.1 0.0 0.0 0.2 0.2 0.4 0.0 0.2 0.1 0.2 0.4 54.7 1.0 0.3 0.0 2.2 5.9 9.0 1.6 0.1 1.6 0.7 0.5 5.4 2.0 0.1 0.0 0.0 1.8 0.0 0.0 0.6 1.4 0.1 0.3 0.0 3.8 0.1 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.2 0.0 1.7 3.1 9.6 2.7 2.0 1.3 1.8 3.4 1.9 1.4 2.3 1.4 0.3 3.2 8.9 29.0 2.5 9.6 17.5 14.1 67.7 2.5 17.3 13.6 4.0 17.2 5.8 18.4 2.1 26.0 2.2 33.0 15.6 5.3 1.2 14.6 1.1 1.8 15.5 0.8 1.8 2.7 3.1 0.7 9.7 12.7 0.0 7.2 0.7 11.9 2.6 5.0 1.3 41.6 12.2 0.8 0.9 1.5 0.3 1.3 14.2 4.7 2.8 12.0 10.3 0.0 0.7 6.2 21.1 0.4 1.0 9.9 28.7 2.9 5.6 2.8 0.0 0.5 1.1 1.0 0.8 28.4 6.1 5.9 3.1 0.4 63.6 6.3 RNH1 "RAI, RNH" ENSG00000023191 "Ribonuclease/angiogenin inhibitor 1" P13489 11 494512-507300 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 262.3;monocytes: 299.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039223, HPA040781" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 22000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" "HPA039223: AB_10795581, HPA040781: AB_10796227" "unprognostic (1.87e-1)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (1.59e-3)" "unprognostic (2.48e-3)" "unprognostic (6.09e-2)" "unprognostic (4.82e-3)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.44e-1)" "prognostic favorable (2.14e-5)" "unprognostic (3.35e-1)" "unprognostic (1.66e-1)" "unprognostic (4.78e-2)" "unprognostic (4.35e-2)" 163.5 137.2 27.3 29.0 41.8 46.3 133.7 42.4 33.9 156.4 28.9 123.0 27.1 140.8 10.0 215.0 119.5 29.7 198.0 26.3 32.5 118.6 111.9 146.7 30.8 48.6 39.7 119.1 89.5 25.6 80.6 27.3 38.2 100.9 8.8 5.6 112.5 31.0 145.9 257.4 91.1 25.3 35.3 113.3 101.1 90.1 38.3 15.6 106.6 21.8 13.9 144.5 160.3 49.4 86.5 123.9 13.2 39.8 66.3 93.8 43.9 70.6 51.3 68.9 58.3 61.9 92.9 41.8 54.3 175.1 41.9 72.7 20.6 76.5 10.4 51.3 104.9 28.2 28.5 65.7 243.3 39.8 90.0 77.1 108.2 40.2 46.7 29.2 47.9 27.7 36.2 71.3 37.7 86.6 30.5 78.4 19.8 45.3 112.6 37.7 22.3 55.8 40.7 34.6 35.7 23.2 41.8 59.1 73.7 7.4 44.6 122.2 77.3 109.3 32.8 39.8 49.5 44.9 53.0 32.2 117.5 81.9 74.3 37.6 246.2 57.3 51.1 298.9 59.9 63.0 55.3 51.1 262.3 48.4 49.8 45.1 17.1 54.2 299.1 71.7 58.4 236.5 27.3 41.8 42.4 33.9 26.3 32.5 48.6 39.7 38.2 35.3 38.3 49.4 156.0 112.2 83.5 18.9 92.3 202.1 239.0 265.0 89.4 102.4 82.0 105.5 83.3 88.6 138.6 79.1 110.5 222.2 85.3 126.6 225.0 188.8 105.1 72.8 132.4 136.1 57.4 59.7 10.9 164.4 217.4 194.9 64.2 82.8 140.2 93.8 101.7 68.6 374.0 168.2 14.5 115.6 148.5 191.8 323.0 42.7 211.6 230.3 193.9 12.2 334.2 144.6 79.3 10.1 70.8 171.6 120.5 179.8 101.7 161.0 139.4 242.3 97.9 146.4 177.5 99.1 178.0 153.4 157.8 140.0 260.0 305.5 96.5 199.7 114.4 217.4 ROBO2 KIAA1568 ENSG00000185008 "Roundabout guidance receptor 2" Q9HCK4 3 75906695-77649964 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;retina: 15.4" "Group enriched" "Detected in many" 24 "Excitatory neurons: 3438.7;Inhibitory neurons: 4706.0" "Cancer enhanced" "Detected in many" "glioma: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 29.8;HEL: 83.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013371, HPA013975" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA 1900000 "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA013371: AB_1856391, HPA013975: " "unprognostic (1.14e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.82e-2)" "unprognostic (5.93e-3)" "unprognostic (3.87e-1)" "unprognostic (2.83e-3)" "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (2.90e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (9.65e-3)" 0.7 2.4 10.1 0.5 13.6 0.0 0.6 0.0 14.2 2.4 0.0 0.8 0.5 2.1 0.4 4.8 0.1 2.3 0.6 10.4 1.7 1.8 1.2 10.0 1.5 14.8 13.1 7.0 1.6 2.8 1.5 5.2 14.3 1.2 0.4 15.4 1.6 5.7 0.1 2.3 0.7 1.4 16.7 2.9 0.7 3.7 4.9 9.3 0.1 0.4 2.2 1.2 1.7 8.1 0.0 0.0 2.2 0.0 7.5 8.1 0.1 0.3 29.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 9.8 83.9 1.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 5.1 9.1 0.0 0.0 1.1 5.1 12.2 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 13.6 0.0 14.2 10.4 1.7 14.8 13.1 14.3 16.7 4.9 8.1 0.7 0.0 0.5 164.6 0.0 1.8 2.0 0.4 19.4 30.8 0.2 1.0 2.4 1.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.2 1.0 1.7 1.1 0.0 0.0 3438.7 0.0 0.1 10.6 0.0 3.2 0.0 2.3 3.3 0.7 0.1 52.2 4706.0 3.0 0.0 0.0 2.8 3.4 3.1 0.1 0.0 54.4 0.0 2.0 0.0 63.3 52.4 0.2 0.0 6.0 0.0 0.8 0.3 0.1 0.1 5.6 0.0 0.1 0.9 2.9 1.1 15.7 1.1 0.1 0.2 40.5 0.5 0.2 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179759-11348330 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 280.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 710000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 36.4 9.3 6.7 13.5 16.3 6.8 22.3 19.1 14.3 18.7 0.8 22.6 16.7 22.0 10.3 16.2 13.6 15.6 17.0 12.1 3.5 14.5 16.5 16.9 10.1 1.7 4.4 19.0 11.7 12.8 5.9 24.9 1.4 17.4 26.2 13.5 14.6 18.1 30.4 8.5 19.2 27.9 2.0 16.4 14.1 7.8 6.4 8.4 13.9 28.9 8.8 21.1 11.0 10.4 17.5 41.7 33.8 33.2 59.7 41.6 21.6 40.4 37.7 25.8 27.1 39.8 37.2 21.9 23.4 64.5 31.3 18.9 24.7 23.4 40.6 31.2 14.7 43.8 70.6 79.7 21.4 24.7 12.1 32.6 14.6 31.9 22.6 21.0 42.0 11.9 38.6 8.6 38.8 14.8 18.2 12.7 18.8 36.9 25.3 21.7 74.2 7.0 14.0 48.8 15.9 16.9 79.6 27.4 27.4 25.5 11.3 13.6 57.3 52.9 38.2 21.2 36.0 6.8 8.9 18.8 22.8 28.2 75.4 0.9 0.4 0.4 0.6 0.4 0.7 0.3 0.4 0.4 0.3 0.5 0.4 0.4 0.6 0.8 0.4 0.6 0.4 0.2 6.7 16.3 19.1 14.3 12.1 3.5 1.7 4.4 1.4 2.0 6.4 10.4 114.5 115.4 79.1 81.3 16.0 39.9 43.0 15.3 21.1 35.7 33.5 41.1 107.0 37.1 53.1 22.0 58.4 26.3 20.4 97.7 1.9 27.1 11.0 53.6 141.2 90.3 21.2 22.5 280.4 39.5 19.1 64.0 18.3 55.3 29.0 36.9 56.0 43.1 19.6 80.8 158.1 92.2 10.2 20.3 27.0 4.9 43.8 30.4 23.2 107.7 20.6 38.4 15.5 99.0 66.9 39.1 43.6 78.6 16.2 53.5 45.3 15.7 32.7 48.5 131.5 70.0 118.5 30.3 24.6 19.9 27.8 31.5 18.5 34.2 54.8 40.7 ROGDI FLJ22386 ENSG00000067836 "Rogdi atypical leucine zipper" Q9GZN7 16 4796968-4802880 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amelogenesis imperfecta, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 105.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 179.2;Rod photoreceptor cells: 149.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 74.6;intermediate monocyte: 62.7;myeloid DC: 61.5;non-classical monocyte: 61.8;plasmacytoid DC: 34.5" "Group enriched" "Detected in all" 6 "dendritic cells: 61.5;monocytes: 74.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041000 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" "HPA041000: AB_10794077" "unprognostic (1.74e-3)" "unprognostic (1.98e-3)" "unprognostic (1.25e-1)" "unprognostic (1.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.95e-1)" "unprognostic (3.13e-1)" "unprognostic (3.79e-3)" "unprognostic (3.22e-2)" "unprognostic (1.21e-1)" "prognostic favorable (9.71e-4)" "unprognostic (5.24e-2)" "prognostic favorable (2.67e-5)" "unprognostic (1.71e-1)" "unprognostic (7.16e-2)" "unprognostic (2.17e-1)" "unprognostic (3.08e-2)" 7.5 24.1 82.9 11.6 84.5 78.0 7.3 81.3 105.6 8.8 64.3 17.6 24.8 7.5 6.6 18.1 14.5 14.4 44.2 91.4 83.9 19.3 19.7 15.5 8.6 84.0 84.9 5.9 22.9 26.4 18.2 7.9 80.9 19.0 7.6 61.9 25.3 16.6 63.1 6.5 21.4 11.3 79.4 15.6 21.1 8.2 96.8 10.1 4.6 32.9 8.7 11.2 6.4 97.6 13.5 18.8 9.5 42.4 12.2 6.2 36.4 9.4 4.6 8.2 3.6 12.5 15.3 5.9 15.1 19.9 5.3 26.7 9.9 28.7 3.2 4.8 13.3 8.0 28.9 28.1 19.8 10.4 6.5 8.3 11.7 12.4 8.3 21.6 14.5 11.5 5.7 3.5 14.1 74.9 9.4 51.0 15.3 15.4 14.2 30.1 26.1 30.1 19.8 18.1 55.3 24.5 38.6 42.4 9.9 11.9 50.9 40.8 22.3 7.3 17.0 52.5 6.5 14.2 17.0 5.2 8.6 40.0 6.5 10.5 74.6 8.1 2.1 62.7 6.6 2.5 5.4 4.9 61.5 2.8 4.7 5.5 6.7 6.7 61.8 34.5 6.1 38.0 82.9 84.5 81.3 105.6 91.4 83.9 84.0 84.9 80.9 79.4 96.8 97.6 7.0 19.2 7.8 17.3 6.7 5.1 28.0 84.4 32.5 179.2 23.0 22.5 58.1 21.5 36.7 27.6 110.5 46.9 11.5 23.4 39.2 22.2 30.3 17.6 8.5 12.0 52.0 38.7 33.2 16.0 73.4 15.9 11.7 7.2 5.7 9.8 24.3 19.7 64.8 25.2 19.2 29.7 69.2 28.7 29.0 57.0 6.8 31.0 12.4 10.3 77.0 102.5 6.2 7.5 90.2 13.5 23.7 19.2 4.6 12.7 65.7 80.8 21.3 149.7 6.6 8.2 15.3 6.5 20.7 24.8 5.8 30.6 9.5 64.7 23.1 22.3 ROPN1B ENSG00000114547 "Rhophilin associated tail protein 1B" Q9BZX4 3 125969160-125983454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 214.2" "Group enriched" "Detected in many" 4 "Early spermatids: 2012.7;Late spermatids: 1967.9" "Group enriched" "Detected in some" 5 "breast cancer: 1.3;melanoma: 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SK-MEL-30: 54.6;WM-115: 18.5" HPA052530 Supported NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 34: Spermatids - Unknown function" "HPA052530: AB_2681861" "unprognostic (7.73e-3)" "unprognostic (1.35e-2)" "unprognostic (2.22e-3)" "unprognostic (2.76e-2)" "unprognostic (7.19e-2)" "unprognostic (3.39e-2)" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (8.15e-2)" "unprognostic (1.96e-2)" "unprognostic (1.09e-2)" "unprognostic (8.18e-2)" "unprognostic (5.91e-2)" "unprognostic (5.01e-2)" "unprognostic (1.74e-2)" "unprognostic (6.89e-3)" "unprognostic (3.78e-2)" 0.3 0.5 1.3 0.2 1.6 0.1 38.2 2.0 1.8 0.2 0.0 0.1 0.1 0.3 22.1 0.1 0.5 0.0 3.0 1.3 1.2 0.3 1.2 0.3 0.6 0.8 1.3 0.3 0.3 0.0 3.0 0.2 0.9 0.7 0.0 1.8 14.6 0.2 0.4 7.0 0.1 0.0 0.5 0.1 0.1 214.2 0.9 0.0 0.7 0.8 0.3 0.4 0.1 2.0 0.0 0.0 0.3 0.2 0.0 0.0 2.9 0.0 0.3 0.2 0.2 0.2 2.4 1.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 1.4 0.0 0.1 1.1 0.2 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.3 0.9 0.3 0.1 0.0 54.6 0.1 0.7 0.7 0.0 0.0 0.5 0.2 0.2 5.4 1.1 0.3 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.6 2.0 1.8 1.3 1.2 0.8 1.3 0.9 0.5 0.9 2.0 0.6 0.0 0.0 1.3 0.3 3.7 0.1 1.4 0.0 0.2 60.1 86.2 18.8 0.0 3.9 0.0 0.0 0.3 2.0 0.0 0.0 0.2 2012.7 3.1 0.1 1.6 0.0 0.0 0.5 0.2 2.5 1.3 0.0 0.1 0.0 0.2 0.0 0.5 0.1 3.3 0.4 0.0 2.0 0.0 2.0 1967.9 19.0 1.5 149.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 9.8 0.0 0.6 0.0 0.1 17.8 0.2 19.7 0.0 1.0 493.4 11.8 0.0 0.6 0.1 0.5 0.0 0.0 1.2 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117287353-117425942 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "epididymis: 58.6;lung: 31.7" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 2: 78.5" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "GAMG: 19.3;HSkMC: 10.1;hTCEpi: 21.7;LHCN-M2: 14.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049098: AB_2680628, HPA072424: AB_2686519" "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.4 0.0 0.0 58.6 0.0 0.1 0.0 0.0 0.6 0.0 0.3 0.1 31.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 2.2 0.4 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 10.1 21.7 0.2 1.9 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.0 0.0 3.1 1.7 0.2 2.1 0.0 0.0 0.0 1.9 3.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.0 78.5 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.8 0.0 3.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.3 1.8 0.2 0.0 0.0 0.0 17.8 0.0 0.0 0.2 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 RPA3 REPA3 ENSG00000106399 "Replication protein A3" P35244 7 7636518-7718607 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 428.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005708 Approved NA NA 17000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA005708: AB_1856411" "unprognostic (2.06e-2)" "unprognostic (2.27e-2)" "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (7.20e-3)" "unprognostic (3.75e-2)" "prognostic unfavorable (5.16e-5)" "unprognostic (5.31e-2)" "unprognostic (2.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (7.41e-2)" "unprognostic (1.08e-1)" "unprognostic (7.24e-2)" "unprognostic (2.61e-1)" "unprognostic (5.83e-2)" 16.4 25.7 12.4 22.9 14.4 46.2 24.4 14.3 19.7 12.5 19.9 25.2 15.8 10.5 37.1 19.6 25.5 10.6 20.5 12.3 15.7 35.7 40.5 14.6 37.9 13.9 13.1 12.7 15.4 46.4 27.2 16.4 15.3 11.5 19.9 34.1 14.5 13.6 18.7 13.3 18.4 9.6 14.7 23.4 20.8 22.5 13.8 51.8 19.3 12.5 35.6 16.3 12.5 15.7 174.1 95.9 94.8 102.3 35.2 31.9 67.2 47.6 44.3 73.0 116.2 92.3 153.1 88.4 45.2 36.0 235.9 129.2 64.5 85.9 106.4 41.1 112.0 48.1 111.9 189.2 15.3 102.5 38.9 23.4 29.9 85.0 59.6 36.0 41.9 168.6 119.5 132.6 70.8 257.0 83.9 198.1 149.9 104.9 125.1 98.3 154.9 141.6 52.3 84.0 70.5 86.8 88.2 91.6 51.0 137.9 122.0 107.4 19.3 60.5 169.1 99.8 113.7 102.7 199.9 167.7 89.7 119.3 118.5 17.9 25.3 27.2 34.1 40.8 40.9 75.4 55.7 44.0 31.9 76.9 45.6 46.3 22.2 29.7 49.0 61.6 68.5 35.7 12.4 14.4 14.3 19.7 12.3 15.7 13.9 13.1 15.3 14.7 13.8 15.7 35.6 38.5 39.5 2.9 93.2 40.5 65.0 160.8 41.5 24.1 54.7 73.9 39.0 60.1 89.5 71.7 10.4 152.2 53.2 61.9 273.9 84.8 96.9 144.8 34.9 35.7 25.3 218.2 5.2 105.4 257.5 43.3 39.8 61.8 53.9 43.2 36.0 154.5 131.4 16.8 5.6 75.1 83.4 48.7 54.2 24.4 39.1 49.9 56.9 1.9 68.2 63.7 56.7 6.0 5.8 64.1 70.4 24.5 75.8 25.9 74.3 428.6 269.9 44.7 6.6 34.7 46.9 112.7 65.9 59.6 34.4 66.2 68.7 46.1 90.5 66.2 RPLP1 LP1 ENSG00000137818 "Ribosomal protein lateral stalk subunit P1" P05386 15 69452814-69456205 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 28402.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003368 Supported "Endoplasmic reticulum,Cytosol" NA NA 2000000 "Cluster 30: Non-specific - Translation" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA003368: AB_1079845" "unprognostic (5.04e-3)" "unprognostic (2.26e-2)" "unprognostic (2.02e-2)" "unprognostic (4.29e-2)" "unprognostic (6.32e-2)" "unprognostic (1.35e-1)" "unprognostic (4.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.30e-1)" "unprognostic (2.36e-1)" "unprognostic (2.79e-1)" "unprognostic (9.55e-2)" "prognostic unfavorable (2.30e-9)" "unprognostic (7.75e-2)" "unprognostic (1.57e-1)" "unprognostic (2.59e-1)" "unprognostic (5.83e-2)" 1779.5 1664.6 852.0 893.4 872.7 2781.2 1895.2 821.7 1109.7 2465.3 920.5 2035.4 1200.3 1805.3 349.4 2773.4 1670.9 579.0 2121.7 813.6 844.4 1703.1 1566.2 1439.7 1583.3 871.6 857.5 3354.5 2003.6 264.6 924.6 565.5 866.0 1991.6 449.1 157.6 1705.8 417.0 4746.4 4498.6 1693.4 529.7 892.5 1992.0 2147.0 492.5 873.6 643.5 1140.9 761.4 1017.9 2099.9 2372.6 891.4 1890.5 1882.4 827.9 1919.4 1172.4 1394.2 1770.4 1615.7 960.9 892.0 711.8 1918.7 1861.9 2622.2 2346.4 869.5 811.2 2521.6 1296.6 1287.5 193.1 2639.9 3956.6 2208.5 2153.1 1914.5 2045.2 1976.4 1931.2 1782.1 2199.9 653.6 1219.6 1438.9 1092.7 2265.9 2127.7 2160.7 642.2 1757.0 2163.4 5781.3 3098.7 1172.2 1802.9 2192.5 2696.6 3893.7 876.0 2002.9 1319.3 2558.5 1620.5 1978.2 6979.8 742.8 1633.9 4449.5 1915.7 1273.2 2851.6 1535.0 2672.3 4382.2 7690.0 2245.6 1524.1 4968.6 1076.9 2903.3 5350.5 1819.3 3182.4 3677.4 5811.2 9096.0 6532.4 4349.4 6100.6 7551.7 6871.8 6057.1 733.9 5147.0 2138.6 6392.6 5921.8 13416.9 852.0 872.7 821.7 1109.7 813.6 844.4 871.6 857.5 866.0 892.5 873.6 891.4 3508.0 1891.0 3795.4 16.0 11229.3 24186.3 18565.6 9896.5 18630.1 626.6 14197.1 19613.8 1854.3 3877.6 5293.4 2265.9 350.3 9217.3 6668.2 2484.5 5141.7 5608.7 475.1 2702.4 5765.4 5131.7 2926.5 6423.8 19.7 7158.4 12076.7 5235.1 3541.4 4232.4 2605.7 4287.7 5261.2 6536.1 8166.9 373.5 22.5 7238.9 2396.6 8309.7 12226.0 1764.3 8447.2 6779.7 9051.8 28.1 11829.2 4015.4 6451.2 15.6 42.8 7495.3 5127.5 4732.9 10308.0 16198.4 5565.3 8039.9 2204.8 1167.3 2530.9 5356.8 5872.6 690.3 1864.1 18779.3 28402.5 9502.3 9179.6 6940.6 8549.1 17342.5 RPS18 "D6S218E, HKE3, KE-3, KE3, S18" ENSG00000231500 "Ribosomal protein S18" P62269 6 33272075-33276511 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast myoepithelial cells: 26385.3;Suprabasal keratinocytes: 31942.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050159, HPA055007" Approved Supported Cytosol NA NA 120000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA050159: AB_2681035, HPA055007: AB_2682668" "prognostic favorable (9.81e-4)" "unprognostic (1.76e-1)" "unprognostic (2.67e-1)" "unprognostic (7.74e-2)" "unprognostic (4.00e-2)" "unprognostic (3.95e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.67e-1)" "unprognostic (4.63e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.15e-10)" "unprognostic (7.00e-2)" "unprognostic (4.00e-2)" "unprognostic (2.85e-1)" "unprognostic (9.19e-2)" 3268.2 2353.2 1862.8 2097.6 1883.3 6071.7 6110.7 1827.2 2345.5 3989.9 1782.7 3060.6 2024.5 2386.7 2877.9 4570.6 3069.7 1608.3 1778.5 1806.3 1863.3 2052.0 2248.2 2034.3 4842.9 1889.4 1840.1 6497.6 5554.4 1294.1 1412.1 1956.1 1895.2 2780.5 2977.4 697.1 3045.6 1415.3 2861.9 6539.3 2565.0 1891.5 1948.2 3087.2 2634.1 789.9 1920.2 3097.1 2084.7 2140.2 4485.9 3011.2 3685.5 1926.5 4603.2 2645.2 3377.1 8930.5 5769.4 11474.6 5486.7 4471.1 6678.3 5939.4 4461.0 6787.2 2617.5 15106.6 4694.9 4890.5 2759.3 3293.1 5472.9 7251.7 4665.1 4722.4 8590.2 5617.0 2868.6 9108.9 11226.3 9771.0 2849.3 12386.6 14318.8 4498.5 13349.4 5436.5 5770.2 4373.8 7686.7 4590.7 5362.0 7880.9 4994.9 10924.1 4652.3 5367.0 3798.3 5853.7 5446.7 10293.5 5524.1 6007.1 3902.3 5714.2 1754.6 8884.0 14781.0 2429.4 6105.7 16713.0 4642.3 2714.4 3129.5 2894.4 5978.6 5376.3 12310.7 11828.5 1512.3 10665.4 3350.2 578.7 1878.9 236.8 2362.1 1653.6 4023.7 5634.6 4545.5 3382.7 3273.4 4515.8 4968.4 4374.8 184.7 3177.0 1265.3 2962.7 3727.6 9405.4 1862.8 1883.3 1827.2 2345.5 1806.3 1863.3 1889.4 1840.1 1895.2 1948.2 1920.2 1926.5 4065.5 1480.8 2569.4 9.4 8276.1 20537.2 16151.5 18150.8 5757.2 343.9 19342.8 26385.3 596.5 4185.0 6755.1 1841.0 231.4 8761.7 5535.7 2348.6 5106.4 4750.1 1164.5 1985.2 7580.0 5826.2 3089.9 3782.1 7.5 12662.2 14558.3 4617.6 2073.4 3457.9 3051.1 5393.6 6329.9 4513.1 6281.1 159.9 8.1 7793.0 4418.8 6115.9 12428.1 3197.4 9895.8 4296.2 8448.8 13.1 6356.1 1521.4 4753.9 5.0 11.5 8283.0 5985.7 4056.9 3499.7 14221.0 5563.4 5974.5 1936.4 683.4 2005.0 7010.5 6802.2 773.3 1827.1 8678.7 31942.8 8778.2 6742.0 7987.5 9896.2 16152.8 RPS6KA2 "HU-2, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 399.6;Excitatory neurons: 204.1;Horizontal cells: 287.7;Inhibitory neurons: 552.3;Oligodendrocyte precursor cells: 244.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 26.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "eosinophil: 22.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.4" "Cell line enhanced" "Detected in many" "ASC diff: 214.5;ASC TERT1: 156.1;HHSteC: 158.5;HSkMC: 141.4;hTERT-HME1: 173.0;hTERT-RPE1: 316.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: AB_2679203, HPA054237: AB_2682425" "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favorable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 34.2 9.0 40.3 8.0 41.0 10.5 27.8 35.0 35.2 18.1 8.6 16.6 6.1 26.0 7.1 20.1 18.7 18.2 61.8 37.8 42.1 13.6 6.6 45.1 7.5 48.3 41.7 29.2 19.4 49.6 27.2 17.9 42.0 14.9 10.3 28.9 14.7 14.2 24.1 16.4 16.5 22.7 35.3 26.0 21.4 7.7 47.3 5.9 36.3 30.5 7.3 24.5 14.9 49.3 9.1 0.0 17.9 26.0 214.5 156.1 0.4 19.3 37.4 10.6 14.6 0.0 5.8 1.1 6.2 68.2 8.4 8.2 9.4 41.8 9.4 4.2 2.3 0.1 40.2 0.4 158.5 0.6 7.2 141.4 29.4 56.6 173.0 316.2 58.0 19.2 0.2 0.2 43.6 1.9 0.8 2.1 4.5 9.1 10.5 3.0 9.2 27.3 11.1 10.1 9.8 68.8 6.7 17.9 24.8 4.4 0.5 14.3 21.7 37.3 3.7 103.8 5.6 5.2 8.4 2.6 24.8 1.2 36.0 0.2 0.6 22.4 0.6 0.8 0.3 0.3 0.6 0.3 0.8 0.5 0.7 0.3 0.5 4.4 2.2 4.7 0.5 0.4 40.3 41.0 35.0 35.2 37.8 42.1 48.3 41.7 42.0 35.3 47.3 49.3 60.9 22.4 46.2 399.6 2.7 4.7 5.4 4.6 3.4 37.1 7.1 5.0 60.0 15.7 11.6 36.8 8.4 0.2 8.0 1.9 11.7 15.2 14.8 20.6 4.6 58.2 5.4 0.0 204.1 24.0 0.3 16.3 16.8 20.3 2.5 10.5 45.3 11.9 7.2 287.7 552.3 5.3 2.0 6.0 6.7 69.3 5.3 8.0 19.6 144.3 3.5 10.1 1.0 244.8 97.7 26.8 1.7 4.5 2.4 9.9 0.3 7.0 9.4 17.1 13.1 10.0 14.5 3.5 2.3 1.2 3.4 0.3 2.0 9.5 1.4 6.6 RREB1 HNT ENSG00000124782 "Ras responsive element binding protein 1" Q92766 6 7107597-7251980 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001756, HPA034843" Approved Supported "Nucleoli fibrillar center,Nuclear speckles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear speckles" "Nucleoli fibrillar center" "HPA001756: AB_1856477, HPA034843: AB_2674357" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (2.93e-1)" "unprognostic (5.05e-2)" "unprognostic (7.38e-2)" "unprognostic (1.23e-3)" "unprognostic (2.53e-1)" "unprognostic (1.32e-2)" "unprognostic (2.45e-2)" "unprognostic (6.51e-2)" "unprognostic (3.31e-2)" "unprognostic (1.16e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "unprognostic (9.54e-2)" "unprognostic (2.92e-1)" 10.9 12.1 4.3 7.8 3.6 31.6 10.8 4.4 2.2 10.2 12.5 10.8 11.9 7.8 5.6 26.2 8.7 6.4 8.3 2.7 4.2 8.2 18.3 9.1 6.5 9.1 6.6 9.8 18.1 12.2 6.3 8.1 6.5 8.1 9.8 5.7 15.0 6.2 16.6 16.2 13.1 6.2 5.4 10.7 10.7 11.6 7.6 9.2 12.0 7.9 7.9 7.9 14.2 5.5 13.1 12.3 10.3 11.9 9.5 6.3 40.1 5.2 7.3 6.2 7.6 20.3 10.0 6.6 10.9 9.9 6.9 9.3 14.7 16.5 5.9 9.2 11.3 24.8 9.6 23.5 13.1 15.0 18.5 10.5 12.7 9.3 13.8 4.2 7.5 15.2 44.6 0.1 6.5 16.5 8.8 35.2 4.9 10.6 10.0 13.1 12.4 10.4 9.0 25.1 2.8 2.6 12.4 16.0 11.1 15.3 12.3 31.0 13.0 11.4 7.1 8.8 6.4 4.1 4.7 9.0 3.3 11.4 9.3 5.5 2.7 6.6 1.5 2.1 1.3 2.2 1.0 1.0 1.7 1.0 1.6 1.3 2.0 3.3 2.4 5.7 0.5 1.7 4.3 3.6 4.4 2.2 2.7 4.2 9.1 6.6 6.5 5.4 7.6 5.5 39.3 25.6 28.7 44.4 19.0 31.5 22.4 30.1 27.9 0.9 27.0 16.9 24.2 31.5 31.4 36.8 70.9 25.8 31.9 62.7 7.9 14.7 46.2 35.5 24.7 22.5 31.8 31.1 3.9 16.3 32.8 16.3 30.1 63.0 10.1 20.7 30.7 70.4 33.4 0.0 0.7 35.7 14.2 66.1 54.9 9.0 19.9 42.1 23.2 78.7 32.6 9.5 13.4 2.0 0.9 22.3 36.3 19.2 27.7 37.1 34.5 16.8 23.9 27.5 52.6 25.5 15.2 13.7 17.4 48.9 34.7 45.8 15.7 27.4 45.0 54.3 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 RSPH14 RTDR1 ENSG00000100218 "Radial spoke head 14 homolog" Q9UHP6 22 23059415-23145021 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 25.0" "Group enriched" "Detected in many" 6 "Early spermatids: 139.7;Late spermatids: 252.0" "Cancer enhanced" "Detected in some" "renal cancer: 2.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 7.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 7.7" "Cell line enhanced" "Detected in some" "GAMG: 3.2;RPTEC TERT1: 4.2;U-266/70: 4.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA018420, HPA050425" Approved Uncertain Nucleoli NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoli "HPA018420: AB_1856496, HPA050425: " "unprognostic (8.81e-2)" "unprognostic (1.57e-2)" "unprognostic (1.15e-3)" "unprognostic (3.80e-3)" "unprognostic (1.97e-1)" "unprognostic (1.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.41e-1)" "unprognostic (1.22e-2)" "unprognostic (8.31e-2)" "unprognostic (7.28e-2)" "prognostic favorable (4.04e-4)" "unprognostic (5.18e-2)" "unprognostic (4.40e-2)" "unprognostic (3.16e-1)" "unprognostic (7.73e-2)" 0.3 2.0 7.7 0.2 9.4 0.2 0.4 5.9 11.8 1.0 9.4 0.6 0.2 0.8 3.5 0.4 12.4 1.3 0.4 8.3 9.9 7.3 0.4 1.5 0.2 8.6 10.9 3.9 0.9 2.4 3.7 0.1 7.7 0.8 0.2 11.4 0.6 1.7 0.7 1.1 0.3 0.3 7.6 0.5 0.7 25.0 7.2 0.1 1.9 0.1 0.2 0.2 0.4 9.5 0.2 2.5 1.9 2.0 0.0 0.9 0.1 0.0 0.5 0.4 0.4 0.4 0.7 0.5 0.7 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.1 0.1 1.0 0.0 0.2 0.4 0.0 1.2 0.0 0.8 0.0 1.0 0.0 0.3 0.3 0.4 0.0 0.6 0.0 0.1 0.0 2.0 4.2 0.0 2.7 0.9 0.0 0.0 0.1 0.1 0.3 0.5 0.0 1.5 0.5 0.1 0.0 4.9 1.9 1.6 1.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 7.7 0.1 1.8 0.0 0.0 0.6 7.7 9.4 5.9 11.8 8.3 9.9 8.6 10.9 7.7 7.6 7.2 9.5 1.9 0.0 0.0 2.0 0.0 0.0 0.9 0.0 0.0 1.1 0.2 0.5 0.1 1.5 3.7 0.0 4.2 0.0 0.2 0.0 7.9 1.0 139.7 17.8 0.5 0.4 0.0 0.0 3.5 0.2 0.0 0.5 0.0 0.5 0.0 1.2 0.7 0.0 0.1 11.8 2.8 0.1 0.0 0.0 0.0 252.0 2.1 0.3 0.0 0.0 0.0 4.6 0.0 1.0 1.1 0.4 0.0 1.9 0.1 0.2 0.0 17.7 29.2 5.1 0.0 0.8 0.9 29.4 8.3 0.0 0.0 0.0 0.4 2.8 0.1 0.3 RTCB "C22orf28, FAAP, HSPC117" ENSG00000100220 "RNA 2',3'-cyclic phosphate and 5'-OH ligase" Q9Y3I0 22 32387582-32412248 "Enzymes, Predicted intracellular proteins" "tRNA processing" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000535, HPA001103" Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 73000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Cytosol" "HPA000535: AB_2666021, HPA001103: AB_1078351" "unprognostic (1.84e-1)" "unprognostic (6.48e-2)" "unprognostic (1.07e-2)" "unprognostic (2.71e-3)" "unprognostic (7.21e-3)" "unprognostic (1.43e-2)" "unprognostic (1.75e-3)" "unprognostic (1.49e-1)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (5.07e-2)" "prognostic favorable (4.25e-5)" "unprognostic (6.91e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" 43.5 44.5 33.3 39.0 36.0 31.4 51.2 37.5 40.8 37.7 35.6 56.1 93.9 43.9 43.7 49.4 46.5 32.6 45.8 33.5 38.1 75.9 75.2 36.3 45.6 36.7 37.0 45.6 45.8 73.0 39.8 45.5 39.1 45.9 73.8 44.1 47.2 47.4 71.1 76.9 79.1 56.0 38.3 43.7 48.4 32.0 36.3 72.9 41.5 63.6 87.9 53.9 39.2 40.2 116.1 101.9 125.0 94.3 106.8 79.1 99.3 98.8 118.5 154.6 145.9 133.2 45.9 28.5 64.6 116.1 95.2 76.7 144.7 143.5 198.6 144.3 144.8 81.4 83.0 122.1 73.4 192.4 71.2 78.3 93.7 153.3 147.8 85.1 141.3 78.5 98.2 78.7 114.3 96.4 82.5 66.4 71.7 133.4 91.7 126.0 134.7 147.1 106.0 99.0 128.3 71.1 107.2 68.5 129.2 130.6 75.5 73.8 107.3 84.8 124.8 74.7 96.5 54.4 46.6 102.1 87.8 85.6 113.4 112.5 135.3 89.2 93.0 151.3 104.4 143.5 96.6 97.4 161.4 150.4 114.8 99.1 13.2 125.7 118.7 90.4 131.7 156.3 33.3 36.0 37.5 40.8 33.5 38.1 36.7 37.0 39.1 38.3 36.3 40.2 32.0 32.1 33.4 15.3 40.3 60.5 54.9 84.9 47.8 51.6 35.4 27.6 35.8 47.1 60.6 35.0 20.9 112.6 43.0 74.8 66.5 108.4 4.8 46.3 28.6 45.4 46.7 36.4 22.4 95.6 87.9 35.8 45.9 53.8 42.6 50.5 41.0 58.3 85.4 52.2 19.6 62.2 116.0 47.4 45.9 10.8 35.1 43.2 30.2 25.3 80.0 66.9 34.0 28.6 35.1 106.5 62.1 47.8 36.0 64.3 178.2 146.9 48.2 56.9 26.3 35.4 43.0 67.0 65.1 52.7 76.0 97.8 34.1 59.3 61.3 73.8 RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;liver: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.1;Excitatory neurons: 14.1;Muller glia cells: 11.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 8.0;basal ganglia: 20.0;cerebellum: 20.9;cerebral cortex: 24.3;hippocampal formation: 12.7" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Cell line enhanced" "Detected in many" "NB-4: 38.2;REH: 53.9;SCLC-21H: 31.3;SK-MEL-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 1900000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (3.44e-1)" "unprognostic (8.90e-3)" "unprognostic (1.21e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (3.07e-1)" 1.6 2.6 8.0 0.5 20.0 0.6 1.0 20.9 24.3 3.6 0.0 1.6 2.2 5.1 0.0 3.5 1.9 0.1 2.7 12.7 0.0 2.1 12.8 2.2 0.4 0.5 0.0 2.4 3.7 0.4 4.9 0.4 0.3 1.5 0.1 0.6 2.0 0.4 0.6 7.9 2.1 0.2 0.0 8.5 1.8 1.9 0.4 0.8 3.5 0.2 0.2 0.5 2.8 1.8 7.9 3.8 2.3 5.5 0.0 0.0 1.2 0.8 0.0 0.6 0.3 6.0 2.2 0.4 2.5 0.1 3.7 12.8 1.4 3.2 0.0 0.2 13.4 0.1 3.2 0.9 1.3 0.3 0.4 0.0 4.1 0.0 0.3 0.0 0.0 3.7 0.4 0.3 0.0 11.0 4.1 38.2 8.7 2.3 6.7 53.9 0.0 0.4 0.5 3.3 31.3 5.0 3.7 2.7 25.9 0.5 3.1 1.1 0.0 0.5 14.2 0.1 0.2 0.1 1.0 0.9 0.4 7.8 0.1 0.0 0.0 0.0 4.6 0.0 10.8 0.0 4.0 4.6 0.2 0.1 2.4 5.1 0.0 0.8 0.0 1.2 3.0 1.7 8.0 20.0 20.9 24.3 12.7 0.0 0.5 0.0 0.3 0.0 0.4 1.8 1.4 3.2 0.0 7.5 0.2 5.1 4.0 1.6 1.8 12.1 2.9 2.4 2.2 0.0 0.6 0.0 4.2 0.2 1.9 3.0 0.0 2.9 2.0 1.2 4.8 2.0 0.0 0.4 14.1 4.3 7.6 1.6 0.0 1.6 0.0 0.4 1.1 3.0 1.3 6.7 2.6 2.6 0.0 0.0 0.7 0.5 0.3 1.7 1.8 2.8 0.7 11.3 2.1 2.5 2.4 3.4 0.4 0.0 0.1 3.9 0.6 0.0 0.0 4.9 0.0 0.2 1.0 0.1 1.2 2.0 5.5 0.0 2.5 0.1 2.1 3.5 RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.6;Cone photoreceptor cells: 37.5;Excitatory neurons: 43.5;Horizontal cells: 33.7;Inhibitory neurons: 18.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.9;HaCaT: 10.8;hTCEpi: 10.1;T-47d: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Yes NA 35000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: AB_10963229" "unprognostic (5.23e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (7.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "unprognostic (6.21e-2)" "unprognostic (2.55e-3)" "unprognostic (6.32e-3)" "prognostic unfavorable (7.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (3.15e-2)" 4.0 3.1 4.6 0.3 4.0 0.0 6.4 0.0 9.2 2.1 0.0 0.4 0.1 0.8 0.2 1.3 1.5 0.6 2.3 12.3 0.3 1.6 2.6 1.6 0.1 0.0 0.5 0.9 1.8 1.3 5.9 0.3 0.0 3.4 0.1 8.5 4.4 2.0 1.8 9.6 0.5 0.3 0.0 1.1 0.7 0.8 1.9 0.2 1.4 0.4 0.1 1.5 2.2 0.0 1.4 1.6 1.8 2.5 2.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.0 0.0 0.1 10.9 0.2 10.8 4.6 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.1 0.0 3.6 0.0 0.0 2.5 0.1 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.8 0.3 1.2 0.0 0.0 2.2 0.0 0.3 0.8 1.7 0.2 13.3 0.1 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.0 0.0 9.2 12.3 0.3 0.0 0.5 0.0 0.0 1.9 0.0 1.0 0.0 2.2 1.6 0.1 2.7 0.2 0.0 1.8 20.6 5.4 4.3 3.0 1.5 1.3 3.7 37.5 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.7 0.0 0.0 43.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.1 3.3 1.8 33.7 18.6 0.0 0.0 0.3 0.4 1.1 0.0 0.1 3.6 7.5 0.0 1.8 0.0 8.5 1.7 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.5 10.0 0.0 0.0 0.6 0.0 0.2 0.5 2.8 0.0 0.2 0.0 0.0 0.3 RTN4RL2 "NgR2, NGRH1" ENSG00000186907 "Reticulon 4 receptor like 2" Q86UN3 11 57460528-57477534 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 39.1;liver: 40.7;thyroid gland: 30.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.9;Cholangiocytes: 12.8;Excitatory neurons: 16.7;Hepatocytes: 14.0;Oligodendrocyte precursor cells: 9.5;Spermatocytes: 10.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 44.1;Karpas-707: 67.5;REH: 42.3;RPMI-8226: 134.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "amygdala: 13.5;cerebral cortex: 23.8;hippocampal formation: 21.0" "Intracellular and membrane" NA NA 27000000 "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (6.27e-3)" "unprognostic (2.02e-2)" "unprognostic (4.57e-2)" "unprognostic (8.40e-2)" "unprognostic (8.51e-2)" "unprognostic (7.64e-2)" "unprognostic (6.83e-2)" "unprognostic (3.72e-2)" "unprognostic (7.27e-2)" "unprognostic (2.41e-1)" "unprognostic (1.09e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (3.05e-7)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" "unprognostic (5.16e-3)" "unprognostic (2.18e-2)" 4.1 0.7 19.0 0.3 39.1 0.8 3.5 0.0 27.3 2.1 0.0 1.0 1.1 2.0 0.2 1.6 1.7 3.0 3.3 25.2 0.0 2.8 40.7 2.6 0.4 0.0 0.0 1.1 2.4 3.7 3.6 1.9 0.0 1.6 0.1 1.0 3.4 0.3 1.7 4.3 1.1 0.7 0.0 1.0 1.5 1.8 0.0 1.9 30.5 0.4 0.3 1.2 1.6 8.2 7.4 10.1 7.6 13.1 3.1 4.4 1.0 0.1 2.9 0.3 2.7 1.3 1.4 0.2 0.2 0.4 4.3 0.2 11.9 0.2 0.1 1.7 4.7 2.3 1.1 7.2 4.4 1.7 44.1 11.9 1.3 1.1 1.1 1.3 0.1 12.9 1.6 67.5 0.1 1.4 0.2 5.3 13.3 0.5 7.6 42.3 5.4 134.0 0.1 0.2 14.0 1.2 1.1 0.6 7.7 0.6 8.5 2.0 0.1 0.5 22.7 3.1 2.4 4.1 9.2 1.4 16.7 7.3 5.8 0.0 0.3 0.0 0.0 0.6 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 19.0 39.1 0.0 27.3 25.2 0.0 0.0 0.0 0.0 0.0 0.0 8.2 1.7 0.0 0.0 2.0 0.4 5.7 0.4 0.3 2.8 19.9 2.1 1.5 0.4 12.8 0.1 0.0 0.0 0.0 0.9 0.2 3.9 1.3 2.6 0.6 0.9 2.1 1.8 0.8 16.7 0.6 5.5 1.6 0.5 2.1 0.0 0.0 1.1 14.0 0.4 0.0 1.1 0.6 0.0 0.0 2.1 1.3 0.3 0.6 1.8 3.7 0.5 0.8 2.1 9.5 1.2 0.8 0.1 1.2 0.0 1.0 0.0 1.1 0.0 1.4 6.6 1.0 5.4 10.2 1.7 1.1 2.8 0.0 0.9 0.1 0.2 0.2 RUFY1 "FLJ22251, RABIP4, ZFYVE12" ENSG00000176783 "RUN and FYVE domain containing 1" Q96T51 5 179550554-179610012 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038804 Approved Supported "Nuclear speckles,Vesicles,Cytosol" NA NA 25000 "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Vesicles, Cytosol" "Nuclear speckles" "HPA038804: AB_10673290" "unprognostic (3.17e-2)" "unprognostic (2.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.50e-1)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (9.74e-2)" "unprognostic (1.31e-1)" "unprognostic (2.73e-2)" "unprognostic (3.60e-1)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" "unprognostic (5.85e-2)" 28.2 33.1 9.6 13.4 10.5 13.3 26.1 9.8 10.2 27.2 11.3 29.1 9.4 27.5 8.1 33.9 24.5 8.8 20.4 9.5 10.1 24.1 21.3 26.6 14.2 10.2 10.0 23.9 24.4 13.5 22.7 9.0 10.1 22.4 8.2 7.4 25.8 8.6 33.8 33.1 25.9 7.8 9.9 35.2 24.2 10.9 10.0 13.6 24.7 10.1 11.5 26.3 27.2 10.6 13.9 22.5 11.8 15.7 22.3 18.2 13.4 24.2 17.2 14.1 16.3 22.0 31.6 22.4 13.4 29.6 16.2 12.6 21.9 31.6 16.4 71.2 16.6 39.2 17.1 16.0 22.8 22.0 20.7 18.5 17.1 9.5 27.0 24.6 15.5 12.5 16.2 20.8 12.7 42.0 23.5 15.2 12.6 15.0 10.5 20.9 8.4 20.9 23.5 22.4 11.7 16.7 35.4 22.5 13.2 14.8 18.0 26.6 18.8 18.3 6.2 10.0 19.3 12.8 21.2 39.8 16.9 39.0 17.2 14.9 4.8 11.9 2.2 5.1 1.3 3.8 2.7 2.3 4.2 5.7 1.9 2.4 7.9 1.8 7.1 4.8 4.5 29.8 9.6 10.5 9.8 10.2 9.5 10.1 10.2 10.0 10.1 9.9 10.0 10.6 19.8 35.3 30.8 30.0 23.6 10.3 11.5 11.7 16.5 9.3 17.8 17.5 22.8 28.6 23.1 14.7 20.9 21.7 15.7 20.0 9.8 19.7 8.0 28.2 21.9 20.9 10.8 27.7 31.8 14.4 15.8 19.7 19.9 20.0 29.8 20.4 12.5 14.1 31.1 11.8 28.4 17.5 8.2 30.7 21.0 3.4 23.0 137.2 10.6 21.5 43.7 11.9 15.5 23.1 33.9 22.1 18.5 27.1 18.3 14.2 14.1 34.0 32.8 12.0 6.6 20.8 17.8 11.1 8.4 21.9 11.4 21.2 19.5 25.0 15.3 10.2 RUNDC3A "RAP2IP, RPIP8" ENSG00000108309 "RUN domain containing 3A" Q59EK9 17 44308413-44318670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 208.4;pituitary gland: 98.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.4;Early spermatids: 24.4;Enteroendocrine cells: 39.0;Excitatory neurons: 46.1;Horizontal cells: 32.0;Inhibitory neurons: 30.4;Late spermatids: 83.4" "Group enriched" "Detected in many" 5 "glioma: 8.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 62.5;SH-SY5Y: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023548, HPA070733" Enhanced Supported Enhanced Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA023548: AB_1856069, HPA070733: AB_2732162" "unprognostic (3.66e-2)" "unprognostic (3.77e-2)" "unprognostic (3.50e-3)" "unprognostic (1.58e-3)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (3.87e-3)" "unprognostic (2.29e-1)" "unprognostic (4.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.42e-3)" "unprognostic (1.34e-1)" "unprognostic (8.87e-3)" "unprognostic (1.07e-2)" "unprognostic (5.17e-2)" "unprognostic (9.39e-2)" "unprognostic (1.84e-1)" 0.3 14.3 149.2 0.4 159.5 2.3 0.3 93.0 208.4 0.2 45.6 3.4 1.2 0.5 0.2 0.8 0.2 0.3 1.8 169.4 105.3 1.8 0.2 0.4 0.2 108.0 106.4 0.8 3.8 3.1 98.3 1.5 108.5 0.8 0.6 31.2 0.3 0.3 0.1 7.9 1.3 0.5 79.2 1.6 2.3 15.2 109.4 0.4 1.4 0.3 0.1 0.2 0.7 135.7 0.0 0.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 4.3 0.0 1.4 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.9 0.2 0.0 0.5 0.3 0.3 0.1 0.1 1.1 0.3 0.1 62.5 40.3 0.3 0.0 0.3 0.1 0.5 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 149.2 159.5 93.0 208.4 169.4 105.3 108.0 106.4 108.5 79.2 109.4 135.7 0.1 0.0 0.6 17.3 0.0 0.3 0.3 0.0 0.0 55.4 0.2 0.3 1.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 3.9 1.3 24.4 0.2 0.3 0.2 39.0 18.7 46.1 3.1 0.0 1.0 0.0 0.2 0.0 0.5 0.4 0.0 0.2 32.0 30.4 0.5 4.1 0.3 0.5 83.4 1.5 0.3 0.0 4.7 0.1 6.5 1.0 16.1 12.5 1.0 1.2 3.4 0.0 0.4 0.0 0.8 0.0 16.8 0.0 0.8 0.5 1.4 1.3 0.0 0.4 0.1 0.1 3.0 0.1 0.3 RUNX2 "AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1" ENSG00000124813 "RUNX family transcription factor 2" Q13950 6 45328157-45664349 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 10.7" "Cell type enhanced" "Detected in many" "dendritic cells: 55.8;Early spermatids: 128.3;Inhibitory neurons: 95.2;Microglial cells: 128.4;Plasma cells: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 22.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 39.3;Karpas-707: 62.3;RH-30: 51.8;U-698: 55.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB008374, HPA022040, CAB062561, CAB068226, HPA070715" Enhanced Enhanced Nucleoplasm No No "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB008374: AB_590789, CAB062561: AB_2665599, CAB068226: AB_2665598, HPA022040: AB_1846086, HPA070715: " "unprognostic (1.49e-1)" "unprognostic (8.90e-3)" "unprognostic (3.99e-2)" "unprognostic (2.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-1)" "unprognostic (1.23e-1)" "unprognostic (3.70e-2)" "unprognostic (3.18e-1)" "prognostic unfavorable (3.97e-9)" "prognostic unfavorable (2.24e-4)" "unprognostic (5.52e-2)" "unprognostic (5.35e-2)" "prognostic unfavorable (6.66e-5)" 1.7 0.7 1.1 4.3 1.0 9.7 2.8 1.2 1.4 6.7 0.9 3.7 2.0 1.5 0.8 1.4 0.9 3.4 0.7 1.3 1.5 1.5 0.7 2.7 4.5 1.9 1.8 2.2 0.6 0.6 1.6 1.5 1.9 4.8 3.9 0.1 10.7 2.6 0.8 2.4 6.0 1.6 1.6 3.6 3.2 0.5 2.0 4.5 1.8 0.9 5.6 3.6 4.9 1.9 3.6 1.1 0.8 0.0 3.2 8.3 0.0 3.3 7.9 10.9 15.2 0.0 1.9 0.0 3.8 4.7 4.9 4.3 0.0 3.1 19.7 13.7 1.5 0.0 2.4 0.0 16.7 14.2 0.1 22.5 2.5 9.7 10.9 39.3 0.2 5.6 0.0 62.3 19.7 1.0 0.4 24.7 0.7 3.2 0.5 0.1 51.8 0.0 10.7 7.0 0.0 0.0 2.4 0.1 4.1 9.2 3.6 1.2 0.5 11.1 8.8 17.2 12.1 19.6 0.0 55.2 12.5 5.3 5.0 8.6 0.9 4.5 1.5 0.2 12.9 0.2 3.5 4.0 2.4 0.2 0.6 1.8 6.5 22.1 0.1 15.4 3.2 1.0 1.1 1.0 1.2 1.4 1.3 1.5 1.9 1.8 1.9 1.6 2.0 1.9 0.9 0.0 2.7 4.6 5.7 2.8 16.6 5.3 1.2 0.0 2.0 1.4 2.7 0.0 4.9 3.7 0.0 0.0 55.8 0.3 0.0 0.6 128.3 0.7 3.5 0.8 0.0 3.8 17.4 0.2 0.0 7.0 4.1 0.5 2.5 0.1 1.1 0.8 3.7 0.0 95.2 1.0 20.3 6.7 20.8 20.0 1.2 16.3 7.2 128.4 18.6 0.0 7.2 6.6 5.2 0.4 0.1 2.2 44.4 16.5 0.0 3.3 5.1 0.0 6.6 1.5 6.2 0.8 0.5 1.2 1.6 0.1 21.4 0.2 0.2 28.0 RUNX3 "AML2, CBFA3, PEBP2A3" ENSG00000020633 "RUNX family transcription factor 3" Q13761 1 24899511-24965121 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.8;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "dendritic cells: 336.4;Langerhans cells: 133.9;NK-cells: 251.3;Plasma cells: 87.1;T-cells: 215.4" "Cancer enhanced" "Detected in all" "melanoma: 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 124.9;Karpas-707: 155.6;SK-MEL-30: 92.4;U-266/70: 54.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004195, CAB025416, HPA059006" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" Cytosol "CAB025416: , HPA004195: , HPA059006: AB_2683877" "unprognostic (7.75e-3)" "unprognostic (6.51e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.42e-1)" "unprognostic (7.60e-2)" "unprognostic (1.81e-2)" "unprognostic (6.51e-2)" "unprognostic (6.95e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "prognostic unfavorable (5.59e-5)" "unprognostic (1.10e-1)" "unprognostic (4.42e-2)" "unprognostic (3.08e-1)" "unprognostic (1.62e-1)" 3.5 1.4 3.7 21.1 3.6 68.8 3.5 3.8 4.6 19.7 3.7 3.7 5.0 1.6 0.7 2.6 1.6 5.3 1.1 3.6 3.8 1.6 3.7 9.5 34.7 4.7 4.4 0.6 0.9 0.4 0.7 0.9 4.3 1.9 4.2 0.1 4.7 0.8 3.8 11.5 15.0 1.6 4.1 35.1 5.5 2.3 4.3 11.2 1.8 0.7 29.0 6.5 1.5 4.5 0.3 10.4 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.5 0.0 0.5 0.0 19.3 18.4 16.4 0.1 0.4 11.1 0.0 0.7 124.9 1.9 0.4 1.8 0.1 0.0 4.5 42.8 0.1 0.0 0.0 1.1 0.0 0.0 3.1 0.1 155.6 0.0 0.0 1.5 37.9 0.7 0.0 3.2 0.0 0.1 22.7 0.0 0.5 3.5 0.0 7.3 0.1 92.4 2.9 0.0 25.7 0.0 0.0 1.9 0.0 0.5 54.6 40.4 18.2 0.1 42.0 4.4 0.7 1.1 7.0 21.7 4.5 11.3 6.7 7.9 18.7 1.4 5.7 3.9 14.6 1.3 28.7 7.7 1.5 9.2 5.5 3.7 3.6 3.8 4.6 3.6 3.8 4.7 4.4 4.3 4.1 4.3 4.5 4.4 0.0 3.6 0.0 57.7 7.6 0.8 4.6 2.2 0.0 9.8 11.3 2.4 0.0 1.5 1.8 0.0 0.1 336.4 0.5 0.0 0.2 2.3 1.1 1.2 2.4 0.0 13.7 0.0 0.2 0.1 3.3 13.3 2.3 45.2 0.0 2.2 1.5 4.6 0.0 0.0 0.5 0.0 22.9 133.9 1.0 0.0 55.6 46.2 1.0 51.1 0.0 251.3 0.0 0.1 0.1 0.1 0.7 87.1 1.2 0.0 0.3 0.5 0.0 0.0 3.5 3.6 0.3 4.1 2.3 5.8 0.3 215.4 0.1 0.4 0.4 RXRA NR2B1 ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 218.9;Kupffer cells: 134.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.5" "Group enriched" "Detected in many" 5 "granulocytes: 19.5;monocytes: 12.9" "Cell line enhanced" "Detected in many" "HaCaT: 105.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favorable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" 40.5 22.7 33.5 14.5 36.4 18.9 11.2 25.5 29.4 12.2 16.9 16.6 25.8 13.5 8.7 28.5 16.5 13.6 19.4 27.1 30.2 16.0 32.9 18.8 8.2 32.9 31.3 21.7 25.4 45.1 3.5 14.5 30.8 15.6 10.0 5.4 21.7 17.1 106.5 88.1 28.0 11.1 30.4 25.1 14.7 7.9 42.7 6.0 17.6 51.9 7.6 16.2 8.2 22.6 19.6 36.4 14.7 21.9 42.8 19.1 66.7 14.1 16.1 9.6 6.5 20.7 28.0 0.0 25.8 22.5 15.1 105.5 7.7 32.8 2.9 26.3 7.2 0.1 47.5 30.0 20.4 18.8 4.8 29.0 52.1 11.5 10.6 12.9 12.8 1.6 26.0 1.1 8.7 61.8 1.1 59.5 17.5 63.4 16.9 7.4 30.3 36.7 12.2 64.3 17.2 10.5 37.3 46.9 10.6 7.1 44.9 78.8 16.5 16.2 23.4 17.4 9.7 1.7 0.2 0.4 11.6 33.9 12.7 1.3 8.1 6.6 1.4 12.9 0.2 0.3 0.9 1.0 3.2 0.1 0.2 1.2 19.5 2.2 11.2 0.7 1.2 3.2 33.5 36.4 25.5 29.4 27.1 30.2 32.9 31.3 30.8 30.4 42.7 22.6 32.1 32.1 22.9 36.2 4.6 34.5 16.5 21.1 12.5 6.0 16.7 14.4 38.8 72.9 26.2 9.2 25.0 30.1 11.0 72.3 1.9 13.9 4.3 19.8 16.6 28.9 9.6 30.9 9.1 14.1 29.5 23.7 17.9 17.4 1.3 21.3 71.0 218.9 31.9 33.7 17.6 21.2 10.2 134.2 30.0 18.8 32.3 50.4 12.4 10.3 80.4 36.5 14.4 29.1 6.0 15.9 32.4 21.1 7.4 17.7 55.6 19.9 34.4 19.9 19.7 34.6 30.6 0.9 9.4 34.4 46.9 23.9 12.6 15.5 27.5 32.8 S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3719.5;vagina: 1174.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2340.8;Paneth cells: 1098.9;Proximal enterocytes: 1549.1;Squamous epithelial cells: 3205.8;Suprabasal keratinocytes: 3612.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 798.6;HaCaT: 1072.9;HBEC3-KT: 1527.6;hTCEpi: 2232.0;OE19: 1675.1;SK-BR-3: 1579.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" 2.2 0.8 1.5 24.9 1.6 0.2 78.3 1.5 2.0 530.8 1.3 241.0 265.4 5.4 14.7 3719.5 20.4 18.5 4.2 1.5 1.5 70.1 16.3 82.7 0.6 1.5 1.5 1.4 17.7 125.2 5.1 1.1 1.5 19.6 240.0 0.0 550.3 39.0 2.2 608.0 209.0 13.1 1.4 1.3 119.2 0.7 1.7 149.0 98.6 0.0 449.7 32.9 1174.2 1.5 798.6 0.2 0.1 0.2 0.2 0.3 7.4 0.2 0.1 0.2 0.1 97.6 140.1 0.6 2.3 0.2 0.5 1072.9 0.0 1527.6 0.1 0.5 0.3 0.1 10.8 7.3 0.0 0.0 0.9 0.6 2232.0 0.5 20.7 0.3 0.3 0.1 0.6 1.1 0.2 140.0 0.7 1.1 0.4 1675.1 1.9 0.6 0.6 2.8 8.1 51.2 0.7 0.7 2.2 1579.1 2.1 36.5 3.9 1.7 0.0 0.7 0.8 1.1 2.0 0.4 0.8 0.9 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.6 1.5 2.0 1.5 1.5 1.5 1.5 1.5 1.4 1.7 1.5 2.7 60.9 162.6 2.3 4.2 2340.8 448.6 770.5 657.9 0.0 256.2 178.3 5.3 270.2 387.7 35.0 0.0 2.7 2.2 1058.2 49.0 197.5 0.0 37.3 6.4 21.5 153.4 0.0 0.0 65.8 1.5 22.8 85.6 80.3 28.0 0.2 1.1 9.5 0.3 0.0 0.0 660.1 126.1 0.3 213.7 0.0 0.0 3.0 241.9 0.0 2.0 0.0 0.0 0.0 0.1 343.0 1098.9 0.0 7.5 619.3 1549.1 4.9 56.2 0.0 0.0 1.3 27.1 0.0 0.0 3205.8 3612.0 0.3 8.7 13.6 580.9 824.9 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 S1PR5 "Edg-8, EDG8" ENSG00000180739 "Sphingosine-1-phosphate receptor 5" Q9H228 19 10512742-10517931 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;brain: 60.2" "Cell type enhanced" "Detected in some" "dendritic cells: 93.9;NK-cells: 164.8;Oligodendrocytes: 26.6;T-cells: 33.1" "Group enriched" "Detected in many" 5 "cervical cancer: 11.7;head and neck cancer: 8.0;lung cancer: 3.7;urothelial cancer: 6.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 299.4;MAIT T-cell: 184.9;memory CD8 T-cell: 144.9;naive CD8 T-cell: 109.3" "Lineage enriched" "Detected in many" 7 "T-cells: 299.4" "Cell line enhanced" "Detected in many" "HaCaT: 28.5;HBEC3-KT: 10.9;RT4: 18.7;T-47d: 11.6;U-2 OS: 10.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029683 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA029683: AB_10603237" "unprognostic (9.07e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (5.55e-4)" "unprognostic (4.21e-1)" "unprognostic (4.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.55e-1)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.71e-7)" "unprognostic (2.46e-2)" "unprognostic (2.90e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-1)" 0.8 0.4 21.1 0.8 35.7 19.7 0.6 32.4 44.7 5.4 8.6 0.3 0.2 0.3 4.4 12.8 0.2 0.2 0.6 19.7 23.2 0.8 1.6 3.0 1.0 39.0 34.0 0.2 1.4 0.1 0.4 1.7 35.8 2.5 0.1 0.0 2.4 0.5 0.6 18.7 0.3 0.2 26.0 11.1 0.3 0.7 30.1 0.9 0.5 0.2 2.1 2.2 10.9 60.2 1.9 2.8 0.6 0.0 0.0 0.1 0.2 0.6 0.5 0.9 0.5 0.3 0.1 0.0 7.6 0.3 1.2 28.5 1.8 10.9 2.0 0.0 1.8 0.2 2.3 0.0 0.1 0.0 0.1 0.0 5.0 3.0 0.6 0.2 0.0 0.0 0.2 0.0 0.0 3.7 1.1 0.0 4.5 0.6 0.5 0.0 2.1 0.0 0.0 18.7 0.0 0.0 4.7 0.0 0.5 1.9 11.6 3.3 0.0 1.5 10.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.5 0.5 1.2 299.4 0.2 184.9 0.6 36.3 144.9 0.6 0.5 10.8 109.3 3.9 44.5 1.1 0.8 0.6 64.2 21.1 35.7 32.4 44.7 19.7 23.2 39.0 34.0 35.8 26.0 30.1 60.2 1.0 3.2 1.9 0.0 0.6 3.6 2.2 10.9 7.4 0.0 0.1 0.9 0.9 1.5 0.9 0.0 0.0 0.1 93.9 0.0 0.0 0.0 6.2 0.1 0.2 0.6 0.0 0.8 0.1 0.2 0.3 1.7 0.5 0.0 2.5 0.0 1.8 0.3 0.2 0.0 0.1 0.0 0.0 0.8 0.3 2.3 0.0 0.6 0.0 2.8 1.2 0.0 164.8 0.0 26.6 0.2 0.0 0.0 14.7 0.2 0.0 0.1 0.4 0.0 0.0 0.1 1.9 0.0 0.2 4.8 5.1 0.1 33.1 0.0 0.0 0.4 SAMHD1 "AGS5, HDDC1, Mg11, MOP-5, SBBI88" ENSG00000101347 "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1" Q9Y3Z3 20 36890229-36951843 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, DNA replication, Host-virus interaction, Immunity, Innate immunity" "Allosteric enzyme, Hydrolase" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 214.2;Endometrial ciliated cells: 173.8;Kupffer cells: 280.2;Macrophages: 326.4;monocytes: 257.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 510.8;BJ hTERT+ SV40 Large T+: 165.8;BJ hTERT+ SV40 Large T+ RasG12V: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047072 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 91000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane" "HPA047072: AB_2679921" "unprognostic (1.09e-1)" "unprognostic (7.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (4.07e-2)" "unprognostic (2.03e-1)" "unprognostic (3.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.44e-1)" "unprognostic (9.06e-2)" "unprognostic (3.18e-2)" "unprognostic (2.72e-2)" 79.5 39.9 11.9 94.3 12.4 11.5 65.7 11.6 12.2 39.1 33.2 58.4 29.4 33.0 9.1 45.8 81.8 40.2 60.5 11.4 16.6 12.2 26.1 68.0 78.0 16.8 15.0 38.0 42.2 14.0 21.7 36.0 17.9 26.3 28.8 5.5 32.6 18.1 23.8 27.8 55.2 44.1 17.6 94.2 45.0 12.6 18.0 29.3 31.7 20.7 51.2 55.3 39.9 26.4 29.9 10.9 3.7 15.6 510.8 101.8 5.5 10.8 37.7 165.8 187.8 39.1 11.2 64.4 19.9 14.4 94.9 21.2 34.7 27.8 30.9 17.4 20.6 5.3 18.8 30.9 39.3 28.2 5.1 96.4 1.0 45.3 1.9 13.3 26.4 0.0 13.7 18.8 5.4 12.0 0.0 19.2 7.9 18.3 25.9 2.8 21.7 35.3 15.7 8.2 23.0 4.2 20.2 10.2 28.2 4.7 20.5 125.4 13.9 11.5 13.5 25.1 28.5 7.3 20.3 21.7 14.5 3.2 7.1 1.4 147.7 4.8 52.2 174.4 47.0 4.5 55.7 53.3 278.6 3.1 55.5 47.6 18.5 56.2 167.0 96.4 95.8 144.3 11.9 12.4 11.6 12.2 11.4 16.6 16.8 15.0 17.9 17.6 18.0 26.4 48.7 28.9 25.5 4.2 19.4 6.4 2.3 7.8 5.7 5.5 6.9 5.8 17.3 14.3 35.3 1.8 4.2 2.6 214.2 2.6 0.0 10.3 3.3 173.8 12.7 44.3 6.0 30.7 8.6 10.2 3.3 71.4 13.3 40.6 12.6 10.5 42.5 20.1 137.2 6.7 8.5 5.7 8.2 280.2 52.3 4.8 82.3 326.4 5.4 36.5 257.9 25.1 116.4 14.1 3.5 7.5 31.3 96.3 54.8 1.9 1.1 1.9 104.4 2.9 59.2 9.6 31.9 10.2 4.9 12.1 5.8 2.9 102.6 9.7 5.5 4.9 SAMM50 "CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W" ENSG00000100347 "SAMM50 sorting and assembly machinery component" Q9Y512 22 43955442-44010531 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034537 Enhanced Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034537: AB_10602794" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.95e-3)" "prognostic favorable (2.63e-7)" "unprognostic (2.43e-3)" "unprognostic (2.28e-1)" "unprognostic (5.28e-3)" "unprognostic (1.70e-3)" "unprognostic (3.37e-2)" "unprognostic (1.95e-1)" "unprognostic (2.42e-1)" "unprognostic (3.52e-1)" "prognostic favorable (4.43e-8)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (1.60e-1)" 41.7 50.6 26.1 27.0 27.0 32.5 35.8 29.8 30.6 43.4 31.1 35.6 50.8 27.0 29.3 31.7 41.9 29.3 65.5 27.1 29.2 48.8 37.2 22.2 34.6 29.8 28.5 40.0 33.3 114.4 24.4 20.1 30.4 26.5 35.5 25.5 35.2 25.1 240.4 35.9 38.3 27.7 27.0 24.4 43.8 26.1 28.5 34.4 28.1 177.0 37.0 27.9 24.0 28.0 64.6 59.8 57.1 69.5 72.2 75.9 79.8 61.7 65.7 89.1 76.4 86.1 46.0 105.9 44.3 70.8 51.4 75.6 85.4 82.6 79.7 29.4 105.3 57.5 73.9 102.6 50.4 184.0 83.1 88.3 64.7 77.0 35.5 62.3 93.1 49.9 49.9 34.0 80.9 91.7 72.6 72.0 56.0 77.4 70.9 83.8 61.8 85.9 74.4 81.0 34.1 55.4 68.3 72.2 104.1 60.4 67.7 59.8 57.7 57.3 68.8 53.6 51.2 50.1 74.4 82.1 72.0 66.3 58.7 47.5 39.2 46.9 39.8 39.0 55.4 55.1 36.6 40.5 67.7 51.0 37.8 36.0 6.1 39.1 31.8 26.7 45.7 40.2 26.1 27.0 29.8 30.6 27.1 29.2 29.8 28.5 30.4 27.0 28.5 28.0 52.9 35.3 18.9 10.4 31.6 20.6 27.0 72.0 30.7 20.1 32.1 40.9 68.6 18.6 39.5 9.2 8.4 41.6 31.7 36.1 60.7 47.2 40.3 47.3 24.9 35.1 18.6 51.4 12.0 55.5 54.1 24.6 42.3 32.7 27.3 43.9 30.0 41.8 51.1 32.0 12.7 35.2 46.8 28.6 20.5 50.1 26.1 25.0 16.0 12.2 41.4 32.8 33.0 9.5 9.1 43.7 34.5 30.5 31.0 16.2 82.4 116.8 39.9 30.1 19.7 23.2 33.4 45.8 31.2 34.3 22.6 20.5 28.5 69.9 59.8 19.3 SAP130 FLJ12761 ENSG00000136715 "Sin3A associated protein 130" Q9H0E3 2 127941217-128028120 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.3" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Late spermatids: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034664 Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA034664: AB_10603238" "unprognostic (2.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.33e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (2.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.43e-1)" "unprognostic (3.92e-2)" "unprognostic (6.77e-2)" "unprognostic (3.75e-2)" "unprognostic (5.26e-2)" "unprognostic (4.41e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" 9.1 8.6 8.8 8.7 8.5 21.7 8.2 8.5 10.2 10.5 5.1 10.3 8.3 10.4 9.2 10.4 9.6 7.2 8.5 8.1 10.8 7.2 8.3 8.0 10.0 6.4 7.9 11.2 8.7 12.4 14.5 9.0 7.1 8.7 9.7 8.6 9.1 7.9 11.9 12.9 9.8 10.2 6.1 8.5 9.7 47.3 8.0 14.8 8.8 13.0 12.6 9.5 10.3 8.8 35.3 18.9 35.3 28.6 22.9 15.7 38.5 22.0 21.4 33.4 26.2 45.1 14.4 29.4 19.3 25.0 17.4 24.0 39.3 22.7 34.5 16.3 25.2 29.2 16.7 35.9 27.5 25.5 22.2 14.8 16.7 44.1 27.5 17.6 27.0 24.4 35.9 21.1 28.2 39.3 35.6 20.0 36.6 20.7 21.1 24.3 29.0 19.6 17.9 30.7 18.5 22.3 23.2 21.7 13.6 22.1 16.4 17.3 23.2 32.1 34.5 30.1 23.6 29.3 31.2 34.3 26.4 17.0 21.0 2.3 4.2 4.6 5.3 2.7 4.0 2.0 3.8 3.5 3.4 5.0 2.7 3.1 14.0 3.6 8.6 6.2 2.7 3.8 8.8 8.5 8.5 10.2 8.1 10.8 6.4 7.9 7.1 6.1 8.0 8.8 5.4 0.0 10.9 29.0 7.9 7.9 2.3 3.2 5.7 5.2 6.5 5.3 15.2 2.8 3.1 1.8 8.4 11.9 9.4 13.1 0.0 4.9 71.5 4.6 8.6 6.2 6.7 11.6 25.4 4.7 12.8 5.2 8.6 8.7 1.3 5.3 5.3 5.8 7.8 8.4 28.9 7.0 4.1 8.4 6.3 44.2 8.4 7.0 5.4 16.9 4.9 5.0 6.2 26.2 31.0 6.1 7.8 8.2 13.2 4.9 6.5 3.4 4.0 5.8 6.6 4.4 5.5 31.0 17.9 9.2 10.4 19.3 7.6 3.7 7.8 4.3 SAPCD1 "C6orf26, NG23" ENSG00000228727 "Suppressor APC domain containing 1" Q5SSQ6 6 31762996-31764851 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.3" "Cell type enriched" "Detected in single" 15 "Respiratory ciliated cells: 1.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.4;U-2 OS: 1.1;U-937: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071699 Approved "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Cell Junctions" "HPA071699: AB_2686433" "unprognostic (9.25e-4)" "unprognostic (1.32e-1)" "unprognostic (3.41e-2)" "unprognostic (3.28e-1)" "unprognostic (9.34e-2)" "unprognostic (8.02e-4)" "unprognostic (1.63e-2)" "unprognostic (3.80e-2)" "unprognostic (2.01e-1)" "unprognostic (8.16e-3)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "unprognostic (8.15e-10)" "unprognostic (2.65e-2)" "unprognostic (4.45e-1)" "unprognostic (3.57e-1)" "unprognostic (7.98e-5)" 2.7 1.1 0.4 0.0 0.4 0.2 2.5 0.5 0.9 2.4 0.4 3.7 0.0 2.5 0.1 2.5 3.9 0.0 1.2 0.4 0.3 7.4 3.1 2.0 0.6 0.4 0.5 3.8 2.1 0.0 6.1 0.1 0.4 6.0 0.2 1.2 2.3 0.1 1.0 28.3 3.9 0.1 0.4 4.8 2.6 3.6 0.4 0.2 2.2 0.0 0.1 2.5 2.2 0.4 0.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.0 0.5 0.0 0.3 0.2 0.0 0.1 0.5 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.7 0.4 0.2 0.2 0.2 0.5 0.0 0.1 0.7 1.4 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.2 0.2 0.1 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.7 0.1 0.4 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.4 0.3 0.4 0.5 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SART1 "Ara1, HAF, SNRNP110, Snu66" ENSG00000175467 "Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP" O43290 11 65961728-65980137 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Allergen, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031188, HPA031189, HPA031190" Supported Enhanced "Nuclear speckles,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Golgi apparatus" "HPA031188: AB_10600092, HPA031189: AB_10601854, HPA031190: AB_10602289" "unprognostic (2.93e-2)" "unprognostic (1.13e-2)" "unprognostic (1.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "unprognostic (6.99e-2)" "unprognostic (2.52e-3)" "unprognostic (8.15e-2)" "unprognostic (8.97e-2)" "unprognostic (2.10e-1)" "unprognostic (2.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (4.24e-2)" 24.6 18.3 15.5 18.3 16.8 41.6 23.1 15.4 17.4 29.2 14.7 26.0 15.6 29.1 8.0 22.7 25.6 8.6 23.2 14.9 16.1 20.4 21.8 22.9 20.3 16.6 16.2 29.2 25.8 11.7 21.4 14.0 15.9 21.7 7.7 8.0 22.2 14.4 38.1 32.0 24.3 10.9 14.6 32.7 24.8 23.5 15.7 20.9 23.5 13.0 13.3 26.2 24.6 17.9 50.4 60.8 27.2 36.8 26.1 20.7 40.8 37.5 27.2 43.8 28.6 44.2 34.3 56.9 42.4 33.8 52.9 48.7 34.6 35.6 22.0 45.8 33.5 65.6 43.6 41.4 39.0 57.4 52.7 26.2 26.4 40.8 36.3 17.4 27.6 42.3 42.2 39.8 25.6 92.6 74.0 83.5 45.7 27.3 55.9 80.8 39.0 60.7 18.4 33.7 30.5 43.0 35.6 37.2 45.5 12.6 41.7 47.0 40.6 54.5 53.0 53.9 54.1 59.6 49.4 48.3 45.0 28.8 47.0 1.4 2.8 8.1 4.3 3.5 3.6 3.9 4.8 4.4 3.6 3.5 3.5 3.9 4.1 2.8 2.0 3.2 5.4 1.8 15.5 16.8 15.4 17.4 14.9 16.1 16.6 16.2 15.9 14.6 15.7 17.9 17.5 6.4 9.1 7.8 27.8 22.7 24.0 12.2 17.6 19.2 12.2 9.1 9.4 21.5 11.3 16.5 10.4 34.1 27.2 30.5 5.9 23.7 9.0 14.2 16.3 19.8 12.5 32.8 5.1 29.3 31.9 17.6 21.9 16.8 32.4 21.8 21.0 15.6 29.4 16.8 4.8 26.5 16.2 22.5 23.6 8.7 37.0 22.9 17.8 6.5 35.7 23.8 34.0 7.1 7.8 26.3 20.1 33.1 31.2 20.5 28.3 18.5 17.5 26.0 32.9 27.6 34.9 26.7 29.7 18.3 21.7 45.3 28.4 15.5 27.5 18.2 SCAF4 "DKFZp434E098, KIAA1172, SFRS15, SRA4" ENSG00000156304 "SR-related CTD associated factor 4" O95104 21 31671000-31732118 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018319, HPA018668, HPA021504, HPA028807" Enhanced Enhanced Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA018319: AB_1856784, HPA018668: AB_1856783, HPA021504: AB_1856785, HPA028807: AB_10602927" "unprognostic (9.18e-2)" "unprognostic (1.17e-1)" "unprognostic (9.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.88e-1)" "unprognostic (1.85e-2)" "unprognostic (3.99e-3)" "unprognostic (4.31e-1)" "unprognostic (2.19e-1)" "unprognostic (2.66e-2)" "unprognostic (3.28e-1)" "unprognostic (6.11e-2)" "unprognostic (1.85e-3)" "unprognostic (2.87e-1)" "unprognostic (7.65e-3)" "unprognostic (1.10e-1)" "unprognostic (2.16e-3)" 14.1 10.6 6.8 12.7 7.3 13.7 13.2 9.3 9.0 14.9 5.5 14.1 12.3 14.6 9.1 16.1 12.8 8.5 11.3 7.1 9.7 9.6 17.1 14.2 18.4 7.8 7.4 16.1 11.8 11.4 11.2 12.7 7.1 12.5 10.1 10.6 13.0 9.0 17.9 18.5 16.3 9.5 5.4 16.3 13.4 17.5 7.3 18.9 11.4 10.8 17.2 13.3 15.1 8.6 31.4 20.5 40.3 29.4 21.4 16.1 27.4 22.6 23.8 23.7 22.0 39.5 22.2 63.9 13.4 22.3 25.9 18.9 44.3 22.1 25.8 28.6 25.8 50.9 16.8 33.4 24.5 54.8 20.5 18.2 24.6 31.6 27.1 15.1 20.9 25.0 68.4 32.4 19.9 41.7 58.4 39.7 51.7 30.5 17.3 57.1 44.8 21.1 16.5 24.3 27.5 29.7 34.9 26.8 19.7 22.1 20.7 36.7 24.4 24.5 23.6 23.5 23.5 20.6 20.7 72.0 17.6 43.4 23.3 6.6 7.9 10.9 9.7 10.6 9.6 10.9 5.6 9.3 9.7 9.7 6.5 7.2 4.0 7.6 9.6 6.8 5.2 8.1 6.8 7.3 9.3 9.0 7.1 9.7 7.8 7.4 7.1 5.4 7.3 8.6 16.5 6.4 14.5 25.8 46.5 46.7 35.5 15.2 53.5 22.8 23.0 13.8 9.4 18.6 13.8 11.0 25.0 16.6 31.2 39.4 3.9 16.4 9.9 14.9 26.7 19.9 19.8 48.4 34.9 14.0 17.8 21.6 19.4 22.9 11.4 21.9 18.9 24.4 15.7 21.9 34.5 18.7 22.4 23.1 37.8 3.8 22.1 22.7 33.8 36.5 24.5 12.5 32.0 34.7 45.5 17.9 23.4 14.3 23.9 31.2 31.6 6.7 18.2 24.6 13.1 29.9 18.3 25.6 23.9 41.7 41.1 18.9 33.1 12.5 22.2 33.5 SCARA5 "FLJ23907, MGC45780, NET33" ENSG00000168079 "Scavenger receptor class A member 5" Q6ZMJ2 8 27869883-27992673 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 90.0" "Group enriched" "Detected in some" 4 "Fibroblasts: 174.0;Leydig cells: 135.8;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 121 "plasmacytoid DC: 21.1" "Lineage enriched" "Detected in single" 211 "dendritic cells: 21.1" "Cell line enriched" "Detected in some" 20 "ASC diff: 229.1" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 5 "spinal cord: 19.5" HPA024661 Approved NA NA 1400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA024661: AB_1853902" "unprognostic (2.76e-2)" "unprognostic (7.20e-3)" "unprognostic (1.44e-2)" "unprognostic (3.53e-2)" "unprognostic (2.34e-2)" "unprognostic (4.62e-2)" "unprognostic (2.01e-1)" "unprognostic (2.15e-1)" "unprognostic (9.13e-2)" "unprognostic (2.40e-1)" "unprognostic (4.21e-2)" "unprognostic (1.10e-1)" "unprognostic (7.09e-6)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" 60.5 4.0 0.4 7.2 0.8 0.0 34.6 0.8 1.8 16.6 4.9 38.5 8.7 2.9 8.2 21.1 23.7 22.5 90.0 0.6 0.4 1.0 4.1 20.2 2.4 0.3 0.2 11.2 2.4 0.2 5.4 12.5 0.2 8.4 33.7 0.3 29.0 3.3 15.1 31.1 26.3 6.5 0.5 3.3 27.3 11.6 0.2 3.2 21.1 34.5 2.1 77.1 36.8 0.3 0.0 7.9 0.0 0.0 229.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 11.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.1 0.4 0.8 0.8 1.8 0.6 0.4 0.3 0.2 0.2 0.5 0.2 0.3 7.1 0.0 0.0 0.0 0.1 6.5 0.1 0.0 0.6 0.0 0.5 0.6 4.6 0.0 0.0 0.0 0.0 0.1 6.7 0.2 0.0 0.0 1.5 0.7 27.9 2.4 0.0 0.0 0.3 0.0 0.4 174.0 4.1 0.8 0.0 0.0 0.0 0.0 0.4 0.0 2.9 0.0 0.0 0.0 17.0 4.6 135.8 1.3 7.2 5.6 0.0 1.9 0.0 0.0 0.2 0.0 0.0 11.3 0.8 0.1 0.0 0.0 0.0 0.1 0.0 7.4 3.6 0.7 1.1 0.9 6.0 0.1 1.1 44.5 0.3 0.1 SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.6" "Cell type enhanced" "Detected in many" "Adipocytes: 65.9;Endothelial cells: 51.3;Hepatic stellate cells: 62.4;Langerhans cells: 37.7;Microglial cells: 26.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 12.1;REH: 11.5;TIME: 37.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" NA NA 2000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" 15.2 5.0 1.5 3.1 1.8 0.4 12.7 1.4 3.4 5.6 1.4 5.2 0.0 6.0 0.9 2.7 6.5 2.2 11.8 1.6 1.8 7.5 7.5 16.3 2.1 2.7 1.7 2.6 3.1 0.1 3.8 4.3 2.2 4.6 1.2 0.2 4.2 0.0 5.3 3.1 5.4 1.2 1.7 25.6 4.2 1.6 1.7 0.5 18.8 1.9 1.0 5.6 4.6 2.8 0.0 0.1 0.3 0.3 0.0 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.3 12.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 11.5 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 37.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 1.8 1.4 3.4 1.6 1.8 2.7 1.7 2.2 1.7 1.7 2.8 65.9 22.4 17.6 6.5 0.6 3.4 0.4 0.7 1.2 1.2 0.8 0.9 3.5 0.0 2.9 3.7 4.2 0.4 2.0 4.9 1.9 0.4 0.3 0.5 0.9 51.3 0.0 3.4 5.4 0.2 0.2 2.5 4.1 1.1 3.8 0.3 62.4 2.3 9.0 0.0 3.5 4.4 0.0 15.7 37.7 0.4 1.2 10.1 3.6 26.2 4.8 0.7 0.0 0.5 1.1 0.3 1.2 1.2 0.0 0.7 3.0 0.2 3.0 2.0 0.0 2.1 3.0 0.5 0.6 0.3 2.7 1.2 1.0 1.3 2.2 0.8 SCCPDH "CGI-49, NET11" ENSG00000143653 "Saccharopine dehydrogenase (putative)" Q8NBX0 1 246724409-246768137 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 159.5" "Group enriched" "Detected in all" 4 "Early spermatids: 1380.7;Spermatocytes: 822.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 20 "basophil: 872.9" "Lineage enriched" "Detected in all" 26 "granulocytes: 872.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050775, HPA076030" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA050775: AB_2681231, HPA076030: " "unprognostic (4.25e-1)" "unprognostic (3.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (2.83e-2)" "unprognostic (6.43e-2)" "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (5.51e-2)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (2.70e-2)" "unprognostic (9.63e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.93e-2)" 26.6 53.7 35.1 14.4 45.5 35.7 23.6 51.5 43.2 22.6 40.8 27.2 34.4 26.2 17.6 9.3 31.6 21.6 32.8 35.3 45.4 49.8 158.2 21.0 13.5 64.0 45.2 22.4 18.8 36.5 24.3 23.8 64.3 39.4 26.8 31.7 15.3 26.0 60.7 24.1 34.6 24.0 57.0 11.5 28.0 159.5 47.3 20.1 33.5 54.7 10.6 81.5 12.0 86.8 55.3 53.2 37.7 22.8 44.5 55.7 0.5 42.3 58.8 70.1 58.3 32.7 150.6 29.3 53.8 49.0 38.9 17.7 32.4 12.6 71.6 40.8 11.9 49.6 46.9 65.9 41.6 97.1 40.7 37.6 5.9 47.4 4.8 65.7 76.4 60.0 62.9 0.1 70.9 13.5 101.6 122.6 56.5 29.6 41.7 83.8 48.5 0.3 216.6 128.2 42.7 48.0 57.3 2.5 39.0 20.2 42.1 99.6 49.8 32.1 28.5 78.7 110.5 138.0 51.1 17.4 54.7 130.2 43.3 872.9 24.3 44.1 18.1 22.2 22.4 11.2 5.4 15.7 10.7 9.4 7.1 22.0 6.4 34.1 15.4 18.2 4.0 17.1 35.1 45.5 51.5 43.2 35.3 45.4 64.0 45.2 64.3 57.0 47.3 86.8 25.0 6.4 11.5 25.8 8.0 30.1 40.6 54.6 1.8 31.2 42.4 17.5 38.0 55.8 40.5 152.6 18.8 41.4 14.6 42.4 31.3 67.2 1380.7 72.7 39.4 23.6 44.9 54.7 23.7 69.0 17.4 35.7 32.6 111.9 57.2 49.2 22.5 187.8 89.4 6.7 20.5 27.4 52.9 45.7 13.7 245.6 47.5 29.7 48.0 10.3 20.3 67.4 18.6 27.2 37.3 75.2 27.8 47.4 8.3 49.2 138.4 69.7 79.4 39.2 19.7 36.7 39.4 822.3 76.2 5.6 68.5 84.6 17.0 42.8 55.0 201.9 SCGB1D2 "LIPB, LPHB" ENSG00000124935 "Secretoglobin family 1D member 2" O95969 11 62242239-62244812 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 1227.2;cervix: 4002.8" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 3242.1;Glandular and luminal cells: 3417.9" "Group enriched" "Detected in many" 6 "breast cancer: 625.1;endometrial cancer: 226.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 10.4" HPA035318 Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "HPA035318: AB_10610421" "unprognostic (8.76e-2)" "unprognostic (2.14e-1)" "prognostic favorable (3.46e-6)" "unprognostic (2.39e-2)" "unprognostic (5.89e-2)" "unprognostic (4.72e-2)" "unprognostic (1.99e-1)" "unprognostic (6.43e-2)" "prognostic favorable (8.03e-6)" "unprognostic (1.55e-1)" "unprognostic (1.15e-2)" 12.9 4.9 4.1 0.0 4.0 0.0 1227.2 3.2 5.4 4002.8 13.8 0.3 0.1 89.0 355.8 10.1 110.3 0.1 3.1 3.5 4.4 10.1 0.2 0.1 0.1 4.7 5.7 1.1 4.5 0.5 5.2 0.2 4.2 8.6 0.2 1.8 69.2 2.9 7.2 342.4 0.4 0.0 3.5 0.0 0.3 0.2 4.3 0.4 0.6 6.0 0.0 0.2 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.4 0.1 0.0 1.8 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.0 3.2 5.4 3.5 4.4 4.7 5.7 4.2 3.5 4.3 4.6 2.1 0.0 0.0 0.0 1.6 27.4 4.8 0.0 0.0 0.5 647.8 251.6 10.9 0.0 0.0 7.3 0.0 0.0 5.3 0.0 23.5 0.3 0.0 3242.1 409.9 12.0 0.0 0.0 0.0 0.2 0.0 3.6 0.0 3417.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 15.0 823.6 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 46.1 0.0 0.9 0.0 0.2 8.6 0.0 0.0 0.0 7.0 0.1 20.0 0.0 0.0 1.1 SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 2021.0;epididymis: 1372.0" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 2506.4;Glandular and luminal cells: 2597.0" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 971.9" "Region enhanced" "Detected in some" "medulla oblongata: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 8.6" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Vesicles "HPA034584: AB_10602221" "unprognostic (7.73e-2)" "unprognostic (3.77e-1)" "prognostic favorable (1.22e-4)" "prognostic favorable (1.54e-8)" "unprognostic (2.98e-2)" "unprognostic (1.86e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (6.87e-3)" "prognostic favorable (6.36e-4)" "unprognostic (5.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" "unprognostic (3.35e-1)" 0.2 0.0 0.0 0.2 0.0 0.0 57.8 0.0 0.0 2021.0 0.1 12.7 1.3 118.8 1372.0 4.2 238.4 13.4 0.2 0.1 0.4 1.9 0.1 2.4 0.0 3.5 1.4 0.7 17.2 1.1 5.1 0.1 0.8 6.8 16.3 0.0 29.6 15.6 0.0 8.6 1.0 2.2 0.5 0.0 45.9 0.0 1.1 2.7 5.8 0.0 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.1 0.0 0.7 0.1 0.0 1.6 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.5 1.4 0.8 0.5 1.1 0.2 0.6 0.0 4.8 0.0 0.4 0.1 3.8 4.8 0.0 0.0 123.6 71.0 0.0 48.6 10.1 16.5 0.0 0.2 1.6 9.7 3.9 6.6 0.0 2506.4 397.7 7.6 37.1 0.0 0.0 5.3 0.0 3.8 26.5 2597.0 0.0 0.3 0.0 0.1 4.9 0.0 0.0 59.9 10.2 0.3 0.0 0.0 0.0 14.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 15.3 10.8 0.0 0.0 27.0 0.7 0.1 109.3 0.0 0.0 0.0 8.5 0.0 0.0 1.7 0.4 0.0 13.7 0.1 7.0 16.6 SCGB2A2 "MGB1, MGC71974, PSBP1, UGB2" ENSG00000110484 "Secretoglobin family 2A member 2" Q13296 11 62270158-62273160 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "breast: 2805.9;skin 1: 708.1" "Group enriched" "Detected in some" 11 "Breast glandular cells: 2119.6;Breast myoepithelial cells: 1028.8;Melanocytes: 1762.7" "Cancer enriched" "Detected in many" 23 "breast cancer: 823.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 124 "SK-BR-3: 18.0" CAB026270 Enhanced "Secreted in female reproductive system" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "CAB026270: AB_912980" "unprognostic (2.38e-1)" "unprognostic (7.28e-2)" "prognostic favorable (9.57e-8)" "unprognostic (4.17e-1)" "unprognostic (3.75e-1)" 34.4 0.2 0.0 0.0 0.0 0.0 2805.9 0.0 0.0 309.2 0.0 0.4 0.0 4.1 0.0 76.6 0.1 0.0 4.0 0.0 0.0 0.5 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 1.6 1.3 0.0 0.2 0.0 0.0 159.3 0.1 1.8 708.1 0.2 0.0 0.0 0.2 0.3 1.1 0.0 2.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 6.6 49.6 0.3 0.0 0.0 0.0 2119.6 1028.8 0.1 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 1.4 41.9 21.6 11.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 141.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 3.2 1762.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 10.9 0.0 9.2 0.0 0.0 0.0 SCGB2B2 "SCGB4A2, SCGBL" ENSG00000205209 "Secretoglobin family 2B member 2" Q4G0G5 19 34593329-34675699 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 8.6" "Cell type enhanced" "Detected in some" "Astrocytes: 63.6;Excitatory neurons: 32.8;Inhibitory neurons: 45.3;Late spermatids: 31.0;Oligodendrocyte precursor cells: 52.8;Oligodendrocytes: 104.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.2;U-266/70: 1.0" HPA046806 Uncertain "Secreted in other tissues" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA046806: AB_10962373" "unprognostic (9.99e-2)" "unprognostic (3.62e-1)" "unprognostic (9.51e-2)" "unprognostic (1.38e-5)" "unprognostic (4.80e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-2)" "unprognostic (2.73e-2)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-3)" "unprognostic (3.67e-1)" "unprognostic (3.52e-2)" "unprognostic (2.90e-1)" "unprognostic (2.49e-1)" "unprognostic (3.40e-2)" "unprognostic (1.52e-1)" 0.3 0.4 0.7 0.0 1.0 0.1 0.9 0.4 0.9 0.1 0.1 0.2 0.1 0.3 2.6 0.9 0.3 0.2 0.3 0.6 0.7 0.3 0.5 0.5 0.3 1.0 1.0 0.2 8.6 0.3 0.3 0.2 0.9 0.3 0.2 0.6 0.3 0.5 0.7 2.9 0.2 0.1 0.5 0.4 0.3 2.0 1.0 0.1 0.5 1.1 0.3 0.4 0.1 0.9 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.2 0.4 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.4 0.2 0.4 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.4 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 1.0 0.4 0.4 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.4 0.9 0.6 0.7 1.0 1.0 0.9 0.5 1.0 0.9 0.0 0.0 0.0 63.6 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.1 0.0 0.2 0.0 0.0 32.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.3 0.0 0.0 0.0 0.0 31.0 0.0 0.0 3.6 17.8 0.0 0.0 0.0 52.8 104.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 SCGB3A1 "HIN-1, HIN1, LU105, PnSP-2, UGRP2" ENSG00000161055 "Secretoglobin family 3A member 1" Q96QR1 5 180590105-180591499 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 270.0;lung: 508.1;salivary gland: 746.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2883.9;Breast myoepithelial cells: 4199.8;Club cells: 13674.8;Respiratory ciliated cells: 3325.6;Urothelial cells: 3139.7" "Group enriched" "Detected in many" 7 "endometrial cancer: 114.2;lung cancer: 288.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 51.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "NB-4: 2.3;T-47d: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 10000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (7.70e-3)" "unprognostic (4.90e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.36e-2)" "unprognostic (7.87e-3)" "unprognostic (2.00e-2)" "unprognostic (3.20e-1)" "unprognostic (4.88e-2)" "unprognostic (3.55e-2)" "unprognostic (7.19e-2)" "unprognostic (8.74e-3)" "unprognostic (5.43e-2)" "unprognostic (4.62e-1)" "unprognostic (4.50e-1)" "unprognostic (1.50e-2)" 1.8 1.5 1.1 0.2 1.2 0.5 122.4 0.7 1.2 270.0 11.7 0.5 0.6 1.5 1.2 74.8 29.9 2.9 0.7 1.1 5.9 1.5 7.0 508.1 0.4 1.4 1.6 2.0 18.2 0.0 12.6 0.1 1.0 37.9 0.0 0.0 746.5 2.4 0.3 4.9 1.0 0.0 1.2 9.4 50.7 3.0 3.0 0.8 3.1 0.0 0.8 14.5 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 20.3 2.4 17.2 13.3 1.8 3.3 4.5 10.1 0.0 5.9 5.0 0.0 0.0 51.8 0.2 4.3 2.6 1.1 1.2 0.7 1.2 1.1 5.9 1.4 1.6 1.0 1.2 3.0 1.5 36.4 173.1 1441.5 0.0 5.9 0.5 51.2 2883.9 0.6 0.0 1831.7 4199.8 0.4 1554.2 13674.8 0.0 0.0 0.0 30.4 0.1 0.0 20.5 0.1 1.6 0.1 40.5 0.0 10.7 0.2 1.6 0.3 15.2 3.6 1.7 35.3 1.0 68.9 1.1 0.4 0.0 0.0 0.1 1566.5 1.2 0.6 0.2 0.6 14.8 5.4 0.0 0.6 0.0 0.0 0.0 0.1 146.1 0.5 0.0 0.0 214.9 0.0 0.0 3325.6 0.0 0.0 1.6 305.2 0.3 4.4 140.8 0.4 0.0 20.2 0.1 0.2 3139.7 SCMH1 Scml3 ENSG00000010803 "Scm polycomb group protein homolog 1" Q96GD3 1 41027200-41242154 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 125.4;Excitatory neurons: 161.3;Inhibitory neurons: 213.0;Microglial cells: 102.1;Oligodendrocyte precursor cells: 154.3;Oligodendrocytes: 77.9;Spermatocytes: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048898, HPA053292" Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA048898: , HPA053292: AB_2797246" "unprognostic (6.02e-2)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (1.98e-2)" "unprognostic (8.77e-2)" "unprognostic (8.93e-3)" "unprognostic (2.77e-2)" "unprognostic (1.40e-1)" "unprognostic (7.38e-2)" "unprognostic (9.47e-2)" "unprognostic (1.63e-1)" "unprognostic (8.08e-2)" "prognostic favorable (5.80e-4)" 22.0 24.0 15.2 11.3 15.9 17.8 23.2 16.5 18.1 32.0 18.6 54.6 12.7 35.4 20.5 14.0 33.1 15.8 39.3 16.1 16.9 29.8 19.7 20.6 10.4 13.6 14.7 36.3 40.1 34.7 27.6 11.0 13.1 40.4 17.0 21.0 27.5 30.7 44.9 13.3 23.4 24.6 12.2 15.5 32.5 32.8 16.7 16.6 24.1 34.2 10.5 38.9 21.3 14.1 19.5 12.8 29.9 27.5 13.4 25.4 0.1 15.4 26.7 25.2 26.0 12.3 24.6 35.4 11.4 28.1 21.1 4.8 23.3 20.6 21.6 24.7 17.8 16.6 17.7 31.2 58.2 35.7 26.2 27.7 20.5 16.7 40.2 30.5 25.7 43.3 15.7 26.8 25.0 10.6 36.0 30.8 27.7 16.4 13.5 39.3 31.3 21.0 20.4 24.1 21.0 22.5 26.7 21.1 22.1 20.2 18.8 90.7 19.0 26.3 20.4 16.4 28.5 27.1 16.2 38.6 16.5 31.5 24.4 0.6 0.6 1.2 1.6 1.1 2.0 2.4 1.9 1.5 1.9 1.1 1.3 1.1 0.0 1.6 0.2 3.9 1.4 0.9 15.2 15.9 16.5 18.1 16.1 16.9 13.6 14.7 13.1 12.2 16.7 14.1 7.1 9.6 10.8 125.4 9.4 6.6 25.8 11.5 26.7 17.0 16.4 17.0 14.9 18.6 7.4 12.9 16.7 7.3 10.8 7.2 1.9 11.4 9.4 7.2 13.8 9.6 8.4 16.0 161.3 21.3 3.3 11.4 15.3 13.1 5.1 11.9 8.9 7.3 6.2 8.4 213.0 7.4 8.2 3.3 6.5 12.4 16.4 3.2 8.8 102.1 2.7 6.9 2.1 154.3 77.9 12.4 6.2 18.0 20.2 23.3 10.4 18.1 5.8 14.2 19.7 11.9 10.3 54.3 26.1 6.1 3.7 4.8 7.4 3.5 12.4 14.5 SCML4 dJ47M23.1 ENSG00000146285 "Scm polycomb group protein like 4" Q8N228 6 107702154-107824317 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.1;lymphoid tissue: 12.1" "Cell type enhanced" "Detected in many" "dendritic cells: 31.7;Early spermatids: 72.1;Late spermatids: 168.4;NK-cells: 35.0;T-cells: 73.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 48.2;MAIT T-cell: 47.7;memory CD4 T-cell: 74.8;memory CD8 T-cell: 65.7;naive CD4 T-cell: 69.1;naive CD8 T-cell: 59.5;NK-cell: 53.2" "Group enriched" "Detected in many" 6 "NK-cells: 53.2;T-cells: 74.8" "Cell line enriched" "Detected in some" 5 "HDLM-2: 65.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA063326, HPA065958" Approved Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "HPA063326: AB_2684986, HPA065958: AB_2685587" "unprognostic (4.00e-5)" "unprognostic (2.10e-3)" "unprognostic (4.71e-2)" "unprognostic (4.24e-3)" "unprognostic (1.38e-3)" "unprognostic (4.75e-4)" "unprognostic (3.84e-3)" "unprognostic (6.65e-3)" "unprognostic (4.26e-1)" "unprognostic (1.53e-2)" "unprognostic (2.13e-4)" "unprognostic (3.68e-1)" "unprognostic (3.77e-4)" "unprognostic (8.65e-2)" "unprognostic (3.68e-2)" "unprognostic (2.52e-3)" "unprognostic (5.09e-3)" 0.6 0.8 0.8 7.2 0.6 3.3 1.0 1.2 0.7 0.5 0.2 2.3 10.1 0.5 4.6 0.9 0.7 1.4 0.6 0.6 0.9 0.6 1.6 1.7 12.1 0.5 0.5 0.6 0.7 0.2 1.9 0.3 0.3 0.6 2.0 0.9 1.0 0.4 0.4 0.9 8.2 0.5 0.1 7.4 2.8 2.2 1.3 9.3 0.8 0.2 9.8 1.1 0.7 0.6 0.1 0.1 0.1 0.1 0.1 0.3 0.8 0.1 0.0 0.0 0.0 1.4 0.2 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.1 65.1 0.0 0.1 0.4 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.7 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.2 0.1 0.3 0.1 0.1 13.8 0.2 0.1 0.1 0.0 0.1 0.2 0.3 0.1 0.3 0.2 0.7 0.1 0.1 0.1 4.2 0.3 3.5 48.2 0.1 47.7 10.1 74.8 65.7 0.2 5.8 69.1 59.5 6.6 53.2 0.4 1.2 5.8 26.6 0.8 0.6 1.2 0.7 0.6 0.9 0.5 0.5 0.3 0.1 1.3 0.6 0.5 0.0 0.0 0.7 18.0 1.5 0.0 0.0 0.6 0.6 0.4 0.4 1.1 0.0 0.0 0.0 0.0 1.3 31.7 0.4 0.0 1.2 72.1 0.0 0.1 0.7 0.0 1.3 2.7 0.0 0.2 1.0 4.6 0.1 1.3 0.0 1.1 1.8 0.2 1.7 2.5 1.4 0.0 0.8 1.4 168.4 0.9 1.2 3.6 1.9 2.0 0.0 35.0 0.5 0.1 0.1 2.6 0.7 11.6 0.0 5.5 0.4 0.7 0.0 0.0 0.3 0.6 1.1 0.5 0.3 0.1 0.1 73.3 0.0 4.7 0.1 SDCBP2 "SITAC18, ST-2" ENSG00000125775 "Syndecan binding protein 2" Q9H190 20 1309909-1329139 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 141.8;intestine: 136.9;stomach 1: 101.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 782.5;Pancreatic endocrine cells: 755.4;Paneth cells: 948.5;Proximal enterocytes: 470.3;Urothelial cells: 641.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 18.6;OE19: 57.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005804, HPA064490" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA005804: , HPA064490: AB_2732713" "unprognostic (1.96e-2)" "unprognostic (5.44e-2)" "unprognostic (2.37e-1)" "unprognostic (5.85e-2)" "unprognostic (2.54e-1)" "unprognostic (2.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (1.01e-1)" "unprognostic (3.78e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.17e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.37e-4)" 7.3 3.4 19.9 10.1 20.7 0.7 6.9 16.3 24.3 25.8 15.2 85.8 136.9 5.7 9.0 141.8 4.3 41.8 4.6 19.6 20.2 16.0 18.1 20.9 1.3 17.2 17.9 3.5 15.2 2.5 3.9 3.3 17.4 6.5 55.5 1.0 29.8 2.5 2.8 62.9 133.0 3.6 16.9 3.1 101.8 5.6 20.3 1.5 14.6 1.4 13.7 38.2 49.9 18.0 10.9 0.5 1.4 0.5 5.8 5.1 0.9 3.2 6.3 2.8 2.7 2.3 18.6 1.1 2.1 1.2 2.0 8.2 0.5 15.5 1.4 0.4 1.0 0.9 0.6 1.5 5.8 1.1 1.2 1.8 10.8 2.2 2.2 6.0 9.6 2.0 1.5 0.7 1.1 2.6 1.7 3.0 1.3 57.3 0.7 1.6 0.7 2.2 1.2 14.4 2.4 1.9 1.5 9.3 3.6 0.6 0.4 0.9 6.5 1.5 0.6 2.8 1.2 2.8 2.7 1.1 0.7 4.1 0.9 0.1 0.8 1.9 0.9 0.3 0.7 0.2 1.2 0.9 1.0 0.4 1.0 1.8 0.8 0.9 0.6 0.7 2.3 0.7 19.9 20.7 16.3 24.3 19.6 20.2 17.2 17.9 17.4 16.9 20.3 18.0 15.6 16.0 4.2 0.0 4.1 55.7 112.0 198.1 3.4 1.0 4.9 4.8 0.8 72.9 172.6 16.5 0.0 1.8 1.0 782.5 27.4 114.5 17.1 25.8 11.7 14.1 35.9 0.0 0.0 209.7 1.1 4.6 201.8 85.4 8.9 1.0 7.1 5.1 0.9 1.7 0.0 150.8 156.6 1.9 6.4 1.9 1.5 1.8 8.8 0.0 2.3 1.0 2.1 0.0 0.0 755.4 948.5 0.0 0.7 107.0 470.3 1.8 89.6 0.9 0.0 1.7 9.9 5.0 7.6 31.1 95.6 1.6 3.5 2.0 109.2 641.9 SDK1 FLJ31425 ENSG00000146555 "Sidekick cell adhesion molecule 1" Q7Z5N4 7 3301252-4269000 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 12.6" "Cell type enhanced" "Detected in many" "Early spermatids: 96.1;Excitatory neurons: 222.4;Inhibitory neurons: 551.0;Late spermatids: 190.0;Microglial cells: 201.4;Oligodendrocyte precursor cells: 112.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;BEWO: 10.5;RPTEC TERT1: 8.7;RT4: 11.2;SuSa: 10.3;U-2 OS: 13.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011392 Approved Approved Cytosol NA NA 9500000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA011392: AB_1856648" "unprognostic (2.39e-1)" "unprognostic (1.80e-2)" "unprognostic (1.44e-1)" "unprognostic (5.83e-2)" "unprognostic (2.15e-3)" "unprognostic (3.02e-2)" "unprognostic (1.23e-1)" "unprognostic (9.93e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-1)" "prognostic favorable (4.08e-4)" "unprognostic (2.16e-1)" "unprognostic (2.49e-2)" "unprognostic (7.84e-2)" "unprognostic (1.59e-1)" "unprognostic (8.44e-2)" "unprognostic (1.37e-1)" 3.6 0.4 0.4 4.0 1.0 0.8 2.1 0.0 1.6 9.4 4.8 4.0 1.0 3.2 2.6 1.6 2.6 1.4 1.1 3.4 1.0 1.7 0.1 4.0 1.5 1.6 2.1 2.2 12.6 0.8 2.2 1.7 2.5 1.6 1.3 1.5 0.8 4.1 0.9 1.4 2.4 2.7 0.8 5.3 2.0 3.5 1.6 2.5 0.5 1.6 1.9 5.2 2.2 0.5 2.2 1.8 8.5 0.0 0.0 0.0 10.5 0.0 0.0 0.4 0.0 0.0 0.0 0.2 2.4 0.0 3.4 0.2 0.9 0.0 0.2 0.0 5.0 0.0 0.4 0.3 4.1 0.0 0.0 1.7 0.0 0.4 0.5 0.0 0.7 0.1 0.0 0.0 4.2 2.2 0.0 0.0 2.9 0.1 0.0 6.3 5.9 0.0 8.7 11.2 5.3 7.7 0.0 0.0 0.0 10.3 0.0 2.8 0.2 0.0 13.2 0.0 3.8 0.0 0.0 0.0 0.0 1.8 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 1.6 3.4 1.0 1.6 2.1 2.5 0.8 1.6 0.5 1.2 0.0 3.0 31.3 0.1 1.3 0.5 2.3 0.6 22.3 0.6 1.8 20.2 1.5 5.5 5.5 0.0 3.6 1.3 0.0 0.0 1.5 96.1 16.9 57.1 1.9 4.9 0.0 222.4 5.4 0.7 11.6 0.5 9.9 0.0 23.4 1.1 0.0 0.5 1.7 551.0 0.5 0.0 0.3 2.1 190.0 1.8 0.7 5.4 201.4 0.0 0.2 0.0 112.1 14.3 2.2 0.0 5.7 0.0 0.7 0.0 1.5 6.7 1.2 6.6 1.7 7.8 9.8 5.5 0.3 0.4 1.9 0.7 1.4 0.1 0.4 SDR42E1 HSPC105 ENSG00000184860 "Short chain dehydrogenase/reductase family 42E, member 1" Q8WUS8 16 81988855-82011481 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 9.2" "Cell type enhanced" "Detected in many" "Ductal cells: 10.0;Ionocytes: 10.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.3;NK-cells: 2.0;T-cells: 2.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.5;hTCEpi: 12.1;MCF7: 8.3;RT4: 20.6;SCLC-21H: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014388 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA014388: AB_1851226" "unprognostic (2.09e-1)" "unprognostic (4.90e-1)" "unprognostic (9.52e-3)" "unprognostic (3.81e-1)" "unprognostic (3.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.51e-2)" "unprognostic (3.96e-2)" "unprognostic (4.93e-4)" "unprognostic (4.90e-7)" "unprognostic (2.18e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (8.27e-2)" 0.5 0.1 0.0 0.9 0.1 0.4 4.4 0.0 0.1 1.2 0.1 2.4 5.6 1.3 1.9 3.6 1.7 1.1 0.6 0.0 0.2 1.9 1.8 1.6 1.3 0.1 0.1 0.3 3.2 2.1 1.3 0.3 0.1 1.7 1.7 0.0 3.1 0.9 0.0 9.2 4.7 1.1 0.0 0.8 2.6 1.1 0.2 1.6 1.9 0.0 2.4 2.3 2.4 0.0 3.7 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.9 0.0 1.8 0.0 0.4 9.5 0.0 6.5 0.0 0.0 0.6 0.0 1.7 0.0 0.3 0.0 0.0 0.3 12.1 1.5 5.9 0.0 0.0 0.0 1.6 0.0 0.8 8.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 2.5 20.6 8.2 0.0 0.2 4.3 0.0 0.2 0.1 0.0 0.2 0.0 4.3 0.0 0.0 4.0 5.9 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 1.1 2.3 0.7 1.2 0.1 1.0 2.2 1.6 0.0 2.0 0.0 0.1 1.5 0.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.0 1.0 0.0 1.1 0.0 2.7 5.9 3.5 6.1 6.2 0.0 5.8 3.9 2.6 7.2 3.3 1.8 0.0 0.6 1.1 2.7 3.9 10.0 1.3 2.8 0.7 0.5 2.4 0.4 0.0 7.5 0.2 0.4 1.1 3.2 0.0 0.4 0.0 3.7 0.0 0.0 0.0 6.0 10.2 0.0 0.3 2.0 0.0 0.2 1.8 0.0 0.0 0.0 1.0 0.0 0.1 6.3 4.5 0.0 1.1 3.8 9.7 2.9 3.6 0.0 0.0 0.0 0.5 8.4 6.2 5.6 9.1 0.3 1.2 0.1 4.1 4.4 SEC14L1 "PRELID4A, SEC14L" ENSG00000129657 "SEC14 like lipid binding 1" Q92503 17 77088749-77217101 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 430.3;Hepatic stellate cells: 286.3;Late spermatids: 740.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 355.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 355.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 398.1;TIME: 251.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021463, HPA028703" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021463: AB_2670712, HPA028703: AB_10602300" "unprognostic (1.19e-1)" "unprognostic (8.61e-2)" "unprognostic (1.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (7.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-3)" "unprognostic (3.09e-1)" "unprognostic (4.30e-2)" 66.7 54.2 42.6 44.6 63.3 65.5 57.6 75.4 60.7 39.5 36.3 19.5 21.8 24.6 28.2 31.5 27.3 34.3 50.2 49.5 57.5 42.0 25.3 66.9 49.7 64.0 63.0 20.7 30.8 25.1 27.9 76.7 54.6 18.3 19.8 19.0 35.0 16.8 94.1 20.5 21.7 27.1 46.2 49.9 31.7 51.9 63.6 24.1 41.6 54.7 46.2 26.0 20.6 50.9 55.0 45.4 65.6 105.0 27.4 36.3 24.1 47.4 42.0 57.8 49.5 55.7 39.6 143.1 93.3 65.0 71.1 26.3 36.0 47.8 72.6 27.3 50.1 81.1 42.4 75.9 44.4 26.8 39.8 46.6 20.7 47.8 47.8 69.1 398.1 24.3 55.8 136.0 79.2 36.2 28.5 22.4 25.0 25.7 43.7 20.3 104.2 112.2 91.2 26.2 59.5 44.8 51.1 31.3 32.1 58.3 27.9 20.7 251.1 65.4 60.6 35.0 37.7 71.1 64.8 79.9 27.9 22.1 21.6 33.8 19.4 48.9 7.1 28.3 8.9 14.6 6.9 5.3 12.7 10.8 10.9 5.9 355.0 10.0 33.3 18.9 12.5 11.5 42.6 63.3 75.4 60.7 49.5 57.5 64.0 63.0 54.6 46.2 63.6 50.9 430.3 41.7 18.6 55.8 69.4 29.3 23.5 22.5 37.0 31.5 86.5 37.8 17.6 15.7 28.9 27.6 18.8 10.8 77.5 20.3 99.7 18.0 242.6 114.8 46.7 205.9 19.7 86.5 33.0 20.7 10.8 34.0 35.2 240.5 34.7 104.3 286.3 11.1 51.6 37.0 54.6 14.0 61.1 127.2 48.1 740.3 26.4 115.1 35.6 62.8 76.1 31.4 34.0 23.1 44.4 41.8 15.2 17.3 269.1 39.5 9.6 24.8 69.5 17.2 39.5 36.4 36.3 45.1 42.5 25.1 30.4 13.3 51.6 64.3 11.5 39.1 SEC14L2 "C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1" ENSG00000100003 "SEC14 like lipid binding 2" O76054 22 30396941-30425303 "Predicted intracellular proteins" "Transcription, Transcription regulation, Transport" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 86.0;liver: 243.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 146.3;Muller glia cells: 112.6;Pancreatic endocrine cells: 115.2;Proximal enterocytes: 52.8;Rod photoreceptor cells: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.7;naive CD8 T-cell: 2.7" "Lineage enriched" "Detected in single" 7 "T-cells: 3.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 93.9;hTCEpi: 47.3;hTERT-RPE1: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064466 Approved Supported Nucleoplasm,Cytosol NA NA 580000 "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "HPA064466: AB_2685270" "prognostic favorable (3.05e-4)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (5.59e-3)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.63e-6)" "unprognostic (1.25e-3)" "unprognostic (3.76e-3)" "unprognostic (2.23e-1)" "unprognostic (2.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.63e-3)" "unprognostic (1.17e-3)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-3)" "unprognostic (2.01e-1)" 2.8 1.4 33.1 2.6 43.3 4.1 44.4 35.8 37.1 6.0 35.4 3.4 21.6 3.4 86.0 20.6 3.1 7.4 2.4 34.3 39.7 8.0 243.8 2.7 3.1 45.4 39.5 2.6 2.6 11.0 11.1 1.5 33.2 52.3 1.3 64.2 9.3 13.7 0.7 7.0 24.3 3.4 30.4 1.1 5.9 1.3 41.4 4.2 9.0 0.5 4.5 3.2 7.7 32.2 24.8 5.5 5.0 6.4 6.5 16.8 0.4 18.0 15.5 12.0 13.1 1.6 15.9 0.5 5.6 22.7 20.5 20.0 3.0 93.9 13.8 2.2 4.1 0.4 5.4 8.0 9.2 0.0 7.1 11.5 47.3 11.5 20.8 55.5 29.7 4.2 0.1 0.5 22.2 4.0 3.0 0.5 0.1 13.9 7.6 1.2 8.0 0.6 20.7 7.8 2.8 3.1 13.3 3.2 11.2 0.6 14.7 0.5 41.2 15.8 10.4 6.8 12.7 0.3 0.2 0.8 32.4 0.1 12.6 0.0 0.1 0.2 0.5 0.1 0.2 0.4 1.4 0.3 0.0 0.3 3.7 2.7 0.3 0.0 0.0 0.5 0.7 0.8 33.1 43.3 35.8 37.1 34.3 39.7 45.4 39.5 33.2 30.4 41.4 32.2 1.1 3.2 5.8 33.6 1.1 4.1 18.0 25.2 6.8 9.2 36.5 21.7 1.2 12.8 10.3 0.0 16.7 4.2 3.2 0.6 5.9 22.9 8.3 2.9 2.3 2.4 1.2 17.2 9.8 18.7 0.3 5.1 5.6 5.8 5.7 0.7 7.1 146.3 0.5 13.5 6.7 2.0 4.1 4.4 0.4 10.7 1.2 2.6 7.2 1.9 0.2 112.6 0.0 21.6 13.2 115.2 0.0 0.7 2.5 15.3 52.8 8.7 3.9 56.0 0.0 2.8 4.0 0.6 1.2 5.6 2.0 3.0 7.4 0.1 2.1 7.8 SEC14L3 TAP2 ENSG00000100012 "SEC14 like lipid binding 3" Q9UDX4 22 30447959-30472017 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.8;liver: 2.9;retina: 9.0" "Group enriched" "Detected in some" 8 "Muller glia cells: 27.6;Respiratory ciliated cells: 22.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA059450 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: Muller glia cells - Visual perception" "HPA059450: AB_2684024" "unprognostic (2.42e-1)" "unprognostic (2.56e-1)" "unprognostic (1.42e-1)" "unprognostic (5.35e-2)" "unprognostic (2.00e-4)" "unprognostic (3.62e-3)" "unprognostic (6.68e-2)" "unprognostic (3.19e-1)" "unprognostic (2.41e-10)" "unprognostic (1.27e-1)" "unprognostic (2.09e-1)" "unprognostic (4.10e-1)" 0.0 0.1 0.2 0.1 0.1 3.8 0.0 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 2.9 1.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 1.7 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.3 0.2 0.0 0.2 0.0 0.2 0.0 0.1 0.4 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.7 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SEC14L4 "dJ130H16.5, TAP3" ENSG00000133488 "SEC14 like lipid binding 4" Q9UDX3 22 30488902-30505711 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.2;liver: 19.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 6.9;Cholangiocytes: 11.5;Erythroid cells: 26.5;Hepatocytes: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 4.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.0" "Cell line enriched" "Detected in some" 4 "BEWO: 37.7" "Region enhanced" "Detected in single" "thalamus: 1.2" HPA069748 Approved Centrosome NA NA 82000 "Cluster 6: Non-specific - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Centrosome "HPA069748: AB_2686187" "unprognostic (6.98e-4)" "unprognostic (2.72e-2)" "unprognostic (2.40e-2)" "unprognostic (1.03e-3)" "unprognostic (6.78e-2)" "unprognostic (2.07e-2)" "unprognostic (9.88e-2)" "unprognostic (4.93e-2)" "unprognostic (3.34e-2)" "unprognostic (1.56e-2)" "unprognostic (1.88e-2)" "unprognostic (8.87e-2)" "unprognostic (4.06e-8)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "unprognostic (5.98e-2)" 0.1 0.9 0.5 0.1 0.5 8.2 0.2 0.5 0.5 0.5 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.2 19.3 4.4 0.1 0.5 0.5 0.2 0.2 3.3 0.1 0.2 0.5 0.1 0.0 0.4 0.1 0.0 0.0 0.7 0.1 0.1 0.4 0.2 0.5 4.4 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.8 2.3 7.1 0.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.3 2.5 0.0 0.1 0.0 0.1 0.1 0.2 0.1 9.2 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.1 2.4 0.1 0.0 0.1 0.0 0.1 0.1 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.5 0.5 0.5 0.5 0.3 0.3 0.5 0.5 0.5 0.4 0.6 0.8 0.3 22.4 6.9 0.7 0.1 0.1 0.5 0.3 0.0 0.4 0.2 0.3 0.7 11.5 1.4 1.8 0.0 0.1 1.3 0.0 0.0 0.5 0.7 1.8 0.2 0.2 0.0 26.5 0.4 0.0 0.4 0.3 0.0 0.2 1.3 0.2 0.4 22.8 0.1 1.7 0.4 0.2 0.0 0.3 0.3 0.1 0.6 0.4 0.0 0.0 0.1 5.3 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 4.3 0.9 0.0 0.9 0.1 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 SEC14L6 ENSG00000214491 "SEC14 like lipid binding 6" B5MCN3 22 30522799-30546682 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 21.2;parathyroid gland: 30.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 10.5;Cholangiocytes: 11.5;Collecting duct cells: 12.9;Ductal cells: 6.6;Muller glia cells: 18.6" "Cancer enriched" "Detected in many" 7 "renal cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "K-562: 12.3;RPTEC TERT1: 21.8;SiHa: 6.6" HPA067695 Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA067695: AB_2685889" "unprognostic (3.49e-2)" "unprognostic (4.76e-2)" "unprognostic (4.79e-2)" "unprognostic (4.09e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (7.28e-3)" "unprognostic (3.88e-2)" "unprognostic (3.13e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.25e-2)" "unprognostic (8.69e-2)" "unprognostic (8.20e-2)" "unprognostic (2.12e-1)" "unprognostic (2.48e-2)" "unprognostic (6.02e-2)" 1.4 1.4 5.3 0.3 4.6 2.1 3.9 4.5 4.7 3.5 5.9 0.5 0.6 3.2 21.2 0.3 1.7 4.5 0.3 4.4 5.0 8.4 0.4 11.9 0.4 8.6 6.2 2.4 5.5 30.5 2.5 0.5 8.8 1.7 0.3 5.0 0.4 2.6 0.2 10.0 0.5 2.2 5.2 0.4 1.2 5.4 8.7 0.3 0.3 0.8 0.6 0.4 0.4 4.9 0.2 0.1 0.9 0.3 0.0 0.0 1.0 0.1 0.0 0.1 0.0 0.2 0.5 0.3 1.1 0.1 0.1 0.2 0.1 0.0 0.3 0.0 0.0 3.0 0.3 0.3 0.1 0.2 0.4 0.0 0.1 0.1 0.1 0.7 0.0 0.1 12.3 0.2 0.0 0.5 0.1 0.4 0.5 0.0 0.1 0.2 0.0 0.1 21.8 0.2 0.2 0.1 6.6 0.1 0.0 0.2 1.8 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.5 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.3 0.1 0.1 0.5 0.0 5.3 4.6 4.5 4.7 4.4 5.0 8.6 6.2 8.8 5.2 8.7 4.9 0.0 12.8 10.5 0.3 0.2 0.1 0.5 0.0 0.0 0.2 0.4 0.5 0.3 11.5 3.7 12.9 0.0 0.0 0.0 0.0 1.9 6.6 0.0 0.3 0.4 1.0 0.0 0.0 0.7 0.8 0.0 0.2 0.0 1.5 1.3 0.2 0.7 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.6 18.6 0.0 1.5 0.6 1.8 0.0 0.7 0.0 0.1 0.0 2.9 0.0 0.5 0.0 2.7 0.1 0.9 0.4 0.0 0.0 0.1 0.9 0.0 0.0 0.2 SELENOI "EPT1, KIAA1724, SELI, SEPI" ENSG00000138018 "Selenoprotein I" Q9C0D9 2 26308547-26395891 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 22.0;Endometrial ciliated cells: 16.3;Glandular and luminal cells: 15.3;Pancreatic endocrine cells: 13.6;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064125 Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "HPA064125: " "unprognostic (6.29e-2)" "unprognostic (7.46e-2)" "unprognostic (1.38e-3)" "unprognostic (3.05e-3)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "unprognostic (7.44e-3)" "unprognostic (5.00e-3)" "unprognostic (7.79e-2)" "unprognostic (2.55e-2)" "unprognostic (6.65e-2)" "unprognostic (9.40e-2)" "unprognostic (1.52e-2)" "unprognostic (2.95e-1)" "unprognostic (1.76e-1)" "unprognostic (9.87e-3)" "unprognostic (1.42e-2)" 3.6 6.4 7.9 5.5 8.4 12.1 8.1 11.2 10.6 5.4 5.0 8.6 12.3 4.1 5.4 11.1 3.5 4.0 3.9 10.3 9.3 7.9 23.2 4.4 5.7 6.8 7.3 3.5 9.0 17.2 4.5 4.7 8.6 6.2 8.7 9.3 6.2 4.2 7.0 18.3 18.4 3.7 9.7 4.3 7.1 4.4 7.2 6.3 7.1 6.6 6.1 7.5 7.1 10.0 42.7 25.7 20.9 21.0 12.8 10.2 32.0 20.3 9.2 10.0 10.2 54.5 26.6 49.5 24.2 9.5 21.4 34.1 32.4 17.9 14.4 13.7 15.4 31.3 17.5 32.3 12.2 41.9 9.7 8.1 15.6 22.3 21.9 6.1 9.4 17.6 35.9 16.6 13.5 18.4 25.1 20.7 26.8 21.6 17.4 22.6 49.2 25.0 19.3 32.4 45.7 19.4 17.3 36.2 16.4 17.3 17.4 12.4 15.1 17.1 22.0 22.7 31.7 22.6 60.8 65.8 17.5 25.4 15.6 0.0 0.7 0.0 0.9 1.0 0.9 2.5 0.9 1.2 0.7 1.0 1.2 2.0 0.2 0.9 0.9 1.3 1.8 0.4 7.9 8.4 11.2 10.6 10.3 9.3 6.8 7.3 8.6 9.7 7.2 10.0 9.1 12.8 8.7 0.0 3.0 0.0 0.0 0.0 0.0 0.0 12.2 7.1 0.0 0.0 3.1 22.0 0.0 6.1 11.7 0.0 0.0 10.4 0.0 16.3 12.8 3.7 0.0 0.0 0.0 10.4 6.2 2.9 0.0 15.3 1.3 8.6 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 13.6 0.0 0.0 3.9 0.0 0.0 5.6 2.2 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 16.6 4.7 11.5 0.0 0.0 SELP "CD62, CD62P, GMP140, GRMP, PADGEM, PSEL" ENSG00000174175 "Selectin P" P16109 1 169588849-169630193 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 14.7;Endothelial cells: 51.8;Hepatic stellate cells: 33.9;Macrophages: 10.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 8.3;T-reg: 8.8" "Group enriched" "Detected in many" 7 "granulocytes: 8.3;T-cells: 8.8" "Group enriched" "Detected in some" 38 "EFO-21: 36.0;HEL: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002145, HPA002655, HPA005990" Enhanced NA NA 520000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002145: AB_563984, HPA002655: AB_1078480, HPA005990: AB_1078479" "unprognostic (3.37e-2)" "unprognostic (2.98e-4)" "unprognostic (4.11e-1)" "unprognostic (1.46e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.12e-4)" "unprognostic (5.30e-4)" "unprognostic (4.14e-2)" "unprognostic (3.59e-1)" "unprognostic (1.74e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.19e-1)" "unprognostic (8.24e-3)" "unprognostic (1.74e-2)" "unprognostic (7.85e-3)" "unprognostic (1.66e-1)" 11.3 2.3 0.2 11.9 0.6 2.2 10.6 0.0 0.6 8.9 3.7 3.3 5.1 6.4 4.1 5.1 6.7 9.5 6.7 0.3 0.0 5.6 2.5 12.6 7.0 0.2 0.2 1.8 1.2 3.1 2.2 6.3 0.2 6.1 4.1 0.0 2.7 5.7 1.0 3.6 4.8 14.2 0.1 1.0 2.8 0.7 0.7 2.6 4.0 1.8 12.6 14.4 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.4 0.6 0.0 0.2 0.0 1.1 0.5 0.2 0.0 0.1 0.2 0.1 2.1 0.3 0.0 0.1 8.8 7.8 0.2 0.6 0.0 0.6 0.3 0.0 0.2 0.2 0.2 0.1 0.7 0.2 14.7 0.0 3.6 0.3 0.4 3.7 0.1 0.0 0.6 0.0 0.2 0.1 1.9 1.5 0.0 1.8 0.0 2.6 0.1 0.0 0.0 0.0 2.0 0.1 0.1 51.8 0.0 5.2 0.5 0.2 0.0 1.5 0.0 0.0 0.0 0.0 33.9 0.4 0.2 0.0 0.2 0.0 0.0 1.5 3.6 0.1 0.3 10.1 3.6 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.1 3.4 4.1 0.5 0.0 0.0 0.3 SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 100.8" "Cell type enhanced" "Detected in many" "Adipocytes: 40.2;Bipolar cells: 23.4;Endothelial cells: 24.4;Hepatic stellate cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 108.1;HUVEC TERT2: 187.0;RT4: 112.3;SK-BR-3: 170.2;TIME: 338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" NA NA 1700000 7900000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" 33.8 9.0 8.8 8.6 5.7 2.7 31.9 5.1 8.1 28.3 12.0 10.5 13.4 14.5 5.4 100.8 15.6 10.8 22.6 5.0 9.2 49.2 4.8 46.2 3.7 10.2 12.7 3.6 6.7 5.5 11.1 30.4 8.7 32.7 6.3 22.0 24.6 32.5 10.4 75.1 12.5 9.1 6.3 50.7 17.3 2.4 21.8 6.1 27.1 6.1 12.6 27.0 55.4 4.7 13.9 3.1 0.7 14.2 0.2 1.3 3.0 8.0 24.2 6.5 10.2 5.4 6.1 0.5 77.9 1.1 0.7 47.5 6.9 100.7 2.4 0.1 1.8 0.8 108.1 18.5 5.7 1.7 3.2 6.2 55.3 15.1 45.4 90.7 187.0 1.2 2.9 0.1 1.3 12.4 1.5 7.5 8.6 6.2 10.1 11.8 0.0 0.5 7.2 112.3 1.1 2.6 12.8 170.2 0.3 10.4 67.2 7.3 338.6 4.2 31.9 29.7 5.5 0.2 0.0 0.9 0.3 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 5.7 5.1 8.1 5.0 9.2 10.2 12.7 8.7 6.3 21.8 4.7 40.2 0.0 1.1 0.0 0.2 6.8 3.0 9.2 5.7 23.4 10.7 6.0 9.2 1.5 6.6 18.4 10.4 11.2 0.6 5.5 0.0 0.3 0.0 6.5 2.4 24.4 0.0 0.0 0.7 0.8 0.5 1.1 16.3 6.9 0.0 0.2 25.4 0.6 1.4 6.7 1.1 10.7 0.0 0.3 0.8 0.3 0.3 0.2 0.0 3.7 0.0 8.7 0.0 0.0 0.1 6.8 3.8 0.0 0.0 2.5 5.7 0.7 5.4 19.8 0.0 0.5 2.5 0.0 0.4 17.7 8.9 6.3 0.4 0.2 5.2 8.6 SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CAPAN-2: 182.4;RPTEC TERT1: 111.1;RT4: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" 11.9 37.6 20.3 18.0 21.9 9.8 22.5 18.8 21.6 35.1 12.8 50.2 30.2 17.1 8.2 124.4 22.6 17.1 24.9 17.3 21.0 47.7 43.2 20.5 12.0 23.5 24.0 21.6 38.5 18.1 18.6 18.3 21.4 31.4 12.1 27.1 41.2 17.6 7.8 50.9 34.7 13.3 21.0 30.3 32.2 10.7 22.9 13.2 34.2 7.9 13.0 42.2 59.8 26.8 21.2 56.3 4.2 13.2 3.8 2.6 30.4 6.4 13.9 7.8 8.3 7.0 182.4 14.9 69.2 4.7 45.0 97.8 3.7 91.2 6.4 85.4 11.7 19.7 13.5 9.4 15.1 2.6 8.7 10.8 39.1 8.5 17.5 32.5 8.8 4.4 9.6 23.0 4.3 15.6 5.4 8.4 18.7 46.8 51.1 6.4 3.1 33.1 111.1 124.0 13.3 13.5 22.3 35.4 8.5 9.3 24.7 6.0 20.0 6.3 11.4 13.1 14.5 33.0 43.2 7.5 58.8 16.1 6.3 0.0 2.4 0.3 0.9 1.4 0.6 16.9 0.5 0.5 1.2 14.9 0.5 0.6 5.1 0.4 2.8 0.2 0.2 1.5 20.3 21.9 18.8 21.6 17.3 21.0 23.5 24.0 21.4 21.0 22.9 26.8 1.8 16.0 22.5 67.3 29.2 65.0 40.0 51.4 23.9 5.7 29.1 18.9 7.8 8.6 44.6 16.5 25.0 13.9 2.4 47.8 3.9 27.3 0.9 15.6 19.6 4.4 4.2 4.0 23.5 35.5 74.5 6.4 34.1 28.3 0.0 8.6 4.6 16.8 13.3 16.8 28.2 17.5 18.3 6.9 7.5 1.2 13.1 5.5 5.4 2.8 5.3 25.1 1.0 8.0 8.3 44.7 26.1 12.0 8.0 46.9 19.6 4.5 22.6 48.3 19.7 5.7 15.3 0.7 3.2 65.3 57.1 12.4 4.3 5.2 20.2 52.0 SEMA4D "C9orf164, CD100, coll-4, FLJ39737, SEMAJ" ENSG00000187764 "Semaphorin 4D" Q92854 9 89360787-89498130 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 260.2" "Cell type enhanced" "Detected in many" "dendritic cells: 76.5;NK-cells: 92.7;Oligodendrocytes: 310.5;T-cells: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 133.2;HMC-1: 97.2;JURKAT: 89.1;MOLT-4: 120.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015662, HPA023277" Approved NA NA 7500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015662: AB_1856671, HPA023277: AB_1856672" "unprognostic (2.94e-2)" "prognostic favorable (4.17e-4)" "unprognostic (1.12e-2)" "unprognostic (8.22e-2)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (1.27e-1)" "unprognostic (1.58e-1)" "unprognostic (7.79e-2)" "unprognostic (2.74e-1)" "unprognostic (3.18e-3)" "unprognostic (1.50e-2)" "unprognostic (2.29e-3)" "unprognostic (3.05e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-1)" "prognostic favorable (4.06e-5)" 7.2 12.8 73.5 35.1 149.7 28.7 6.1 129.0 122.7 9.1 34.2 10.4 10.6 6.5 12.2 27.3 11.0 12.3 12.1 72.0 88.4 32.0 4.1 14.2 62.4 165.2 145.6 6.5 8.0 6.0 13.8 5.5 147.8 11.9 9.7 5.0 12.0 6.6 88.0 17.4 28.9 5.5 119.1 51.3 16.7 10.6 127.0 43.4 11.8 27.5 49.8 11.4 16.2 260.2 12.7 9.2 8.4 12.4 0.4 0.8 19.0 1.1 0.5 2.6 1.7 6.1 13.8 47.3 5.1 0.2 9.7 6.4 7.5 3.6 1.1 133.2 7.5 20.1 3.3 0.7 1.5 26.4 97.2 0.3 2.8 0.6 0.3 0.3 4.9 89.1 4.8 31.5 0.0 20.9 120.9 33.9 20.6 25.0 0.5 38.2 2.8 13.4 16.5 13.0 19.7 13.1 3.4 8.9 0.3 11.7 10.1 14.4 3.2 0.1 7.6 1.0 6.1 34.9 16.3 6.6 6.0 32.1 7.6 17.2 7.5 38.2 22.0 7.0 13.3 4.3 17.5 18.6 2.6 2.5 19.9 23.2 37.0 9.4 8.1 8.0 17.7 14.5 73.5 149.7 129.0 122.7 72.0 88.4 165.2 145.6 147.8 119.1 127.0 260.2 3.4 6.4 15.7 33.6 35.4 4.6 3.3 2.1 3.4 12.4 9.5 5.5 18.7 5.7 6.9 11.0 2.1 9.0 76.5 1.5 3.9 5.4 2.2 10.9 6.4 5.2 1.8 23.1 44.5 3.3 2.1 6.7 7.7 15.4 42.5 8.0 5.3 1.6 21.6 33.7 17.2 6.3 4.1 28.2 6.1 3.8 7.5 37.4 1.8 49.6 43.7 8.9 92.7 12.1 310.5 3.7 0.7 15.1 53.7 6.5 0.5 14.2 5.7 5.1 0.0 11.4 2.6 0.9 26.1 7.1 5.4 3.7 89.7 2.3 3.3 7.7 SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969518-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 84.6;liver: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.4;Gastric mucus-secreting cells: 27.0;Hepatocytes: 60.5;Intestinal goblet cells: 34.6;Paneth cells: 38.5;Proximal enterocytes: 47.6;Undifferentiated cells: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 31.7;CACO-2: 30.5;Hep G2: 113.8;OE19: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" NA NA 1300000 "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" 2.4 12.7 13.1 5.9 10.9 0.4 3.6 18.9 12.3 6.9 12.8 53.6 53.4 3.5 32.1 3.6 5.9 9.0 3.0 10.0 11.6 19.1 102.4 5.8 2.5 11.2 14.4 18.9 31.3 7.3 9.9 3.9 11.5 20.2 84.6 7.3 8.5 3.0 2.6 18.3 41.2 4.6 9.6 3.1 20.9 3.7 17.0 0.8 15.3 0.8 0.9 4.0 5.0 9.9 0.2 31.7 8.0 3.4 5.0 1.6 6.8 1.2 3.4 1.7 1.7 30.5 5.2 0.5 4.2 1.5 0.6 2.1 8.0 1.4 1.4 0.7 4.9 1.7 3.0 113.8 12.5 1.2 1.0 8.3 1.8 1.6 0.9 22.2 4.4 3.5 3.3 0.4 2.5 2.0 0.5 1.2 1.3 69.1 1.8 3.1 0.7 1.5 7.4 1.0 2.5 12.5 1.1 2.1 3.2 8.7 8.7 1.5 3.0 1.0 3.7 0.8 0.3 1.1 0.6 0.5 0.9 1.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 10.9 18.9 12.3 10.0 11.6 11.2 14.4 11.5 9.6 17.0 9.9 0.3 3.2 1.1 3.9 1.2 0.0 0.6 0.7 0.6 3.5 2.5 2.0 1.2 20.0 0.2 0.0 0.0 8.8 0.0 66.4 0.0 2.7 0.2 1.6 0.7 0.6 8.5 0.8 3.0 2.6 1.9 2.0 27.0 0.3 0.0 3.4 2.2 60.5 0.9 11.8 14.1 34.6 2.0 3.3 0.0 0.2 2.1 0.2 1.8 0.0 0.0 0.9 0.0 3.5 5.5 2.4 38.5 1.2 0.2 3.0 47.6 6.4 2.4 1.6 0.0 0.1 0.4 1.1 1.9 0.5 0.1 2.9 0.2 12.7 45.9 0.9 SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.1;retina: 34.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 68.8;Extravillous trophoblasts: 58.8;Granulosa cells: 65.1;Pancreatic endocrine cells: 91.0;Rod photoreceptor cells: 58.3;Syncytiotrophoblasts: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "HMC-1: 275.8;hTEC/SVTERT24-B: 108.7;U-251 MG: 166.3;U-87 MG: 92.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 38000000 "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA008210: , HPA042273: AB_10806234" "unprognostic (2.00e-1)" "unprognostic (2.72e-1)" "unprognostic (2.02e-2)" "unprognostic (5.81e-2)" "unprognostic (6.49e-2)" "unprognostic (8.61e-2)" "unprognostic (2.54e-2)" "unprognostic (4.18e-3)" "unprognostic (1.33e-1)" "unprognostic (1.39e-1)" "unprognostic (5.18e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.45e-11)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (6.25e-2)" "unprognostic (2.57e-2)" 2.0 2.5 4.6 7.0 11.0 9.9 1.9 19.1 14.4 2.2 0.9 2.4 1.5 2.9 0.9 4.8 1.4 1.8 2.3 5.1 8.2 2.8 1.6 8.1 13.2 19.9 11.6 7.8 0.9 1.9 2.7 16.3 22.9 1.8 0.9 34.6 2.2 1.2 2.0 8.5 10.8 1.1 10.6 60.1 3.5 29.5 17.2 9.4 1.3 0.3 12.9 8.2 2.5 20.2 16.7 0.2 4.8 1.4 6.0 20.1 39.7 75.2 30.1 15.5 23.8 6.5 26.6 0.1 4.3 34.2 12.6 4.9 1.5 4.8 16.0 1.3 0.9 30.0 0.1 8.3 1.3 0.9 275.8 14.3 0.2 108.7 6.0 39.0 0.2 2.0 17.5 10.1 51.2 1.4 4.3 9.9 5.2 0.4 11.3 0.6 3.3 4.4 6.5 7.1 0.3 0.5 0.5 13.4 6.1 4.1 1.0 6.0 3.0 28.8 19.2 14.1 166.3 1.8 1.3 0.3 92.4 3.4 1.5 1.8 0.0 3.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 4.6 11.0 19.1 14.4 5.1 8.2 19.9 11.6 22.9 10.6 17.2 20.2 1.8 3.2 0.0 1.0 22.6 0.4 1.6 3.1 0.6 13.7 1.2 1.3 1.4 0.0 4.0 1.8 68.8 25.6 5.2 0.6 0.0 19.8 0.5 4.6 1.5 5.3 0.0 21.7 12.4 13.9 58.8 1.8 1.5 10.6 8.2 65.1 0.7 0.7 7.2 1.7 5.9 0.0 0.0 0.3 12.0 2.5 3.7 4.8 8.8 0.0 28.6 6.8 1.0 4.0 16.3 91.0 0.1 1.9 6.4 3.3 0.1 0.1 2.0 58.3 0.0 0.2 9.0 0.9 0.8 0.2 1.4 166.4 5.7 22.0 0.0 24.4 SEPTIN4 "ARTS, C17orf47, CE5B3, FLJ40121, H5, hCDCREL-2, hucep-7, MART, PNUTL2, SEPT4" ENSG00000108387 "Septin 4" "O43236, Q8NEP4" 17 58520250-58544368 "Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 1288.2;choroid plexus: 593.0;retina: 404.5" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 52.0;Smooth muscle cells: 38.9" "Cancer enhanced" "Detected in all" "glioma: 8.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 14.0;hTERT-RPE1: 19.4;SK-MEL-30: 32.8" "CAB006855, HPA021587, HPA022905, HPA028424" Enhanced Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "CAB006855: , HPA021587: AB_1856686, HPA022905: AB_1856687, HPA028424: AB_10601690" "unprognostic (1.12e-1)" "unprognostic (5.54e-2)" "unprognostic (8.36e-3)" "unprognostic (8.01e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-2)" "unprognostic (6.88e-3)" "unprognostic (2.73e-2)" "unprognostic (2.76e-1)" "unprognostic (8.02e-2)" "unprognostic (1.97e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (6.40e-3)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (8.75e-3)" 46.6 165.0 832.1 5.0 1011.1 0.5 33.5 861.9 1288.2 13.9 593.0 15.3 4.9 12.4 6.9 5.9 14.2 17.1 56.3 774.4 799.2 31.8 56.6 39.6 14.4 864.7 904.6 15.8 8.7 9.4 23.1 20.9 859.8 8.6 5.3 404.5 9.2 6.5 10.8 11.1 12.1 11.7 798.0 49.5 11.5 25.7 925.2 4.4 23.2 13.7 7.3 12.2 12.1 1080.0 0.0 0.6 1.2 3.6 1.4 0.2 0.6 0.2 0.5 2.1 2.4 0.2 0.5 0.0 5.1 0.8 3.2 0.4 1.8 1.4 0.5 0.3 0.9 1.3 0.3 7.6 14.0 0.1 0.7 7.2 2.9 0.5 2.6 19.4 0.6 1.9 0.0 3.8 0.2 0.5 0.0 0.1 0.6 0.0 0.9 0.2 0.0 1.6 0.0 0.1 3.9 2.1 0.1 0.2 32.8 1.6 0.8 0.4 0.0 0.3 1.6 0.0 1.4 1.0 0.6 0.0 1.1 0.0 0.4 0.0 3.6 0.8 4.9 0.5 1.5 1.6 1.0 1.3 3.7 0.3 1.8 1.4 1.9 1.0 0.0 0.2 0.7 3.6 832.1 1011.1 861.9 1288.2 774.4 799.2 864.7 904.6 859.8 798.0 925.2 1080.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 0.0 0.0 0.0 0.0 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 SEPTIN8 "KIAA0202, SEP2, SEPT8" ENSG00000164402 "Septin 8" Q92599 5 132750819-132807241 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 393.6" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Cardiomyocytes: 14.1;Cytotrophoblasts: 31.0;Extravillous trophoblasts: 12.1;Fibroblasts: 9.5;Hofbauer cells: 12.1;Smooth muscle cells: 8.8;Syncytiotrophoblasts: 10.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005665, HPA036534" Enhanced Approved "Actin filaments,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Actin filaments" "HPA005665: AB_1079910, HPA036534: AB_2797226" "unprognostic (2.06e-2)" "unprognostic (1.13e-1)" "unprognostic (9.24e-2)" "unprognostic (7.10e-3)" "unprognostic (2.70e-1)" "unprognostic (2.15e-2)" "unprognostic (2.86e-2)" "unprognostic (1.41e-2)" "unprognostic (1.58e-2)" "unprognostic (2.97e-2)" "unprognostic (2.38e-2)" "unprognostic (3.12e-1)" "prognostic unfavorable (6.98e-5)" "unprognostic (2.86e-2)" "unprognostic (4.30e-1)" "unprognostic (8.04e-3)" "unprognostic (2.70e-1)" 26.9 19.5 192.8 18.0 273.3 8.3 22.2 279.1 238.2 28.2 111.6 26.3 26.2 18.8 18.5 34.0 21.4 25.2 33.0 188.3 218.5 34.8 13.0 26.2 14.9 319.9 262.0 25.2 23.3 23.9 22.3 44.3 304.7 20.5 26.9 74.6 33.4 20.6 10.9 49.7 25.8 21.3 238.1 14.8 26.8 6.9 250.4 18.0 32.3 12.4 18.6 36.1 31.1 393.6 55.8 26.4 37.3 76.7 50.8 49.5 122.0 58.9 56.2 54.7 66.5 46.6 39.2 0.3 51.1 57.3 32.4 42.3 70.5 96.4 59.9 71.3 50.8 54.4 35.5 40.5 37.2 19.4 76.0 35.9 30.6 25.3 35.8 53.5 77.4 47.7 84.6 10.6 29.7 53.0 63.3 18.2 19.8 33.7 17.0 57.4 43.5 4.7 32.0 141.1 50.0 31.0 50.0 11.5 32.9 107.4 100.6 25.4 80.9 60.6 39.2 15.1 42.5 14.3 14.3 2.0 38.7 28.6 46.5 0.5 1.0 0.0 2.0 0.6 2.0 0.4 1.6 2.5 1.2 0.1 0.4 1.0 0.0 0.2 0.3 0.0 1.9 1.0 192.8 273.3 279.1 238.2 188.3 218.5 319.9 262.0 304.7 238.1 250.4 393.6 7.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 31.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 12.1 9.5 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 10.1 0.6 0.0 0.0 0.0 SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 484.5;liver: 785.6;testis: 432.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 400.4;Endometrial ciliated cells: 175.2;Glandular and luminal cells: 345.3;Hepatocytes: 198.2;Late spermatids: 277.8;Peritubular cells: 144.4" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 261.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" 5.1 484.5 1.8 3.3 2.4 0.0 19.6 2.2 1.7 29.6 3.0 5.3 5.5 31.8 1.2 0.8 26.3 160.5 19.0 1.6 7.2 151.4 785.6 1.0 3.6 3.5 3.8 30.1 173.9 0.2 3.2 0.1 5.3 6.8 1.9 14.0 9.4 153.3 46.4 3.3 3.6 2.1 1.7 112.2 12.1 432.4 2.8 0.9 4.1 152.6 4.7 2.3 4.0 3.7 0.8 0.1 2.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 12.0 12.2 0.0 8.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 261.3 0.3 0.4 0.0 1.7 0.3 0.1 0.0 2.3 4.9 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.5 0.2 3.9 0.1 0.4 17.4 0.2 0.1 7.9 0.9 0.1 0.0 0.5 0.0 0.6 0.4 1.5 0.2 0.1 0.2 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.4 2.2 1.7 1.6 7.2 3.5 3.8 5.3 1.7 2.8 3.7 0.9 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.2 18.9 14.1 0.8 400.4 0.1 33.1 2.1 0.0 0.1 0.0 64.6 103.2 78.7 175.2 19.7 40.3 0.0 2.7 0.0 122.2 0.0 18.2 0.5 345.3 0.0 78.2 2.5 198.2 0.0 8.4 0.0 0.0 0.0 3.2 0.7 277.8 57.2 1.9 0.0 0.0 0.6 5.4 0.0 0.0 0.2 18.3 0.0 144.4 0.0 0.1 0.0 7.5 0.0 1.4 6.6 11.6 1.5 11.1 2.9 0.0 0.6 0.3 1.8 58.7 0.0 0.1 SERPINB10 "bomapin, PI10" ENSG00000242550 "Serpin family B member 10" P48595 18 63897174-63936111 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 60 "bone marrow: 74.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.4;Club cells: 2.7;Erythroid cells: 1.3;Kupffer cells: 1.2;monocytes: 4.7;Respiratory ciliated cells: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;eosinophil: 1.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "U-937: 104.1" "Not detected" "Not detected" "HPA015480, HPA059582" Uncertain Supported Nucleoplasm,Cytosol NA NA 59000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA015480: AB_1855456, HPA059582: AB_2684072" "unprognostic (4.66e-1)" "unprognostic (5.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (9.56e-2)" "unprognostic (2.56e-1)" "unprognostic (4.59e-1)" "unprognostic (1.10e-1)" "unprognostic (3.64e-1)" "unprognostic (1.25e-4)" 0.3 0.1 0.1 0.1 0.2 74.7 0.0 0.5 0.4 0.3 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.1 1.2 0.1 0.1 0.1 0.7 0.1 0.0 0.3 0.9 0.0 0.0 0.6 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.1 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.0 14.5 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.7 0.1 1.5 0.1 0.0 0.0 0.1 0.1 104.1 0.1 0.1 1.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.3 0.1 0.2 0.5 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 4.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.2 SERPINB2 "HsT1201, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 239.1;lymphoid tissue: 81.2;skin 1: 89.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2243.9;Suprabasal keratinocytes: 1053.6;Syncytiotrophoblasts: 439.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.5" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.3;thalamus: 1.1" "Immune cell enhanced" "Detected in some" "basophil: 22.0;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.0" "Cell line enhanced" "Detected in many" "GAMG: 282.7;HaCaT: 699.1;U-138 MG: 807.0;U-2197: 1243.9" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "HPA015480: AB_1855456, HPA076596: , HPA076608: " "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.46e-2)" "unprognostic (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-6)" "unprognostic (3.89e-2)" "unprognostic (3.94e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.55e-5)" 21.0 0.3 0.0 8.6 0.0 36.5 8.7 0.0 1.3 21.0 0.0 0.5 0.1 0.7 0.0 239.1 8.4 0.7 1.0 0.0 0.2 0.2 0.3 2.8 0.0 0.0 0.1 0.3 1.1 0.2 0.1 50.1 0.0 0.2 0.0 0.0 31.2 0.0 0.3 89.2 0.1 1.7 0.0 0.3 0.8 0.0 1.1 2.6 0.1 0.2 81.2 6.6 45.4 0.0 1.4 0.0 0.0 0.8 1.3 0.6 0.2 169.2 179.2 6.0 13.1 0.9 0.4 0.2 0.0 6.1 282.7 699.1 0.0 143.7 118.6 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.5 1.5 13.9 81.7 37.0 1.8 0.6 0.0 0.6 0.4 2.8 0.0 0.2 0.4 0.3 0.2 1.8 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 1.1 0.0 0.6 0.7 15.7 13.9 807.0 0.4 1243.9 0.0 0.2 0.1 0.0 21.6 1.8 96.7 22.0 4.9 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.5 0.0 0.2 2243.9 4.1 82.1 0.0 0.0 0.6 0.1 0.7 0.0 153.4 0.0 0.0 6.2 0.1 0.0 0.0 92.6 0.0 0.1 0.1 5.5 0.0 0.0 0.0 7.1 1.7 11.0 0.0 0.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 26.4 2.9 86.4 0.0 0.0 73.1 94.3 0.0 3.9 0.0 0.0 0.0 0.0 167.2 0.0 0.0 1.0 18.9 0.0 0.0 94.5 0.0 0.0 0.3 14.8 0.0 0.0 94.7 1053.6 439.3 2.5 0.0 0.0 52.0 SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.6;skin 1: 239.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 964.1;Basal prostatic cells: 358.7;Basal respiratory cells: 272.9;Squamous epithelial cells: 535.4;Suprabasal keratinocytes: 1215.3;Urothelial cells: 564.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1279.3;HBEC3-KT: 425.6;hTCEpi: 875.0;hTERT-HME1: 217.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 770000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" 0.6 0.0 0.0 4.3 0.0 0.2 37.1 0.1 0.1 38.5 0.1 4.8 16.7 0.1 0.1 216.6 1.4 2.7 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 9.9 4.5 0.0 37.6 1.7 1.4 239.7 22.1 0.2 0.0 0.0 9.7 2.8 0.0 13.9 0.1 0.0 39.9 90.9 78.7 0.1 80.8 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 73.4 0.1 3.8 0.0 0.1 1279.3 0.0 425.6 0.0 0.0 0.0 0.0 95.8 0.2 0.0 0.0 0.6 0.1 875.0 0.0 217.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 179.9 93.4 0.1 0.0 0.2 0.0 95.1 1.4 0.0 60.2 0.3 0.0 0.3 0.2 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.2 0.9 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 964.1 358.7 272.9 224.3 0.0 5.1 27.3 0.2 0.0 90.0 3.7 0.0 0.3 0.1 14.2 0.0 0.1 9.0 6.2 0.1 5.4 3.5 0.0 0.3 0.0 0.2 5.8 12.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.3 34.6 0.0 57.6 18.6 0.6 1.8 62.2 0.0 0.0 0.0 0.0 0.0 0.1 16.3 51.7 0.0 2.5 85.4 13.5 0.1 85.4 0.0 0.0 0.0 7.1 6.6 2.2 535.4 1215.3 0.1 4.0 0.1 30.6 564.9 SERPINB8 "CAP2, PI8" ENSG00000166401 "Serpin family B member 8" P50452 18 63970029-64019779 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 58.8" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 120.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB034300 Enhanced Approved Nucleoplasm,Cytosol NA NA 920000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB034300: AB_2186486" "unprognostic (8.49e-2)" "unprognostic (4.87e-2)" "unprognostic (4.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (7.71e-2)" "unprognostic (4.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.58e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (8.73e-2)" "unprognostic (3.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.90e-1)" 10.8 9.5 2.6 15.8 3.2 30.3 9.5 3.4 3.6 9.3 3.5 8.6 6.3 4.7 1.5 30.1 4.4 18.1 5.7 2.8 3.9 9.0 37.8 12.1 13.4 5.2 4.0 4.2 7.1 2.7 3.7 7.2 4.8 4.6 9.7 2.3 10.8 3.3 3.0 58.8 8.8 7.3 4.3 7.8 7.1 2.7 4.6 6.5 5.3 2.3 18.3 23.7 17.1 4.5 24.2 4.8 4.0 28.8 13.9 19.7 2.0 75.6 72.9 46.8 46.4 1.0 10.8 0.4 27.2 45.6 23.3 38.3 0.8 48.2 66.3 33.4 0.9 0.0 8.7 2.5 32.1 120.0 10.0 19.1 41.3 63.6 20.9 30.3 51.4 5.1 0.7 13.4 32.9 2.1 2.1 13.5 1.7 3.8 23.6 1.7 10.5 2.1 21.4 27.1 2.3 2.4 15.0 2.3 28.8 3.3 0.8 45.4 79.2 71.0 15.4 8.8 31.1 5.9 1.0 0.1 72.5 69.2 63.0 2.7 44.2 2.0 7.6 34.2 6.8 7.1 6.3 4.7 53.8 9.9 3.3 5.2 12.4 4.6 18.1 28.8 8.9 11.2 2.6 3.2 3.4 3.6 2.8 3.9 5.2 4.0 4.8 4.3 4.6 4.5 6.0 3.2 8.3 0.3 9.1 41.0 25.9 38.9 5.7 0.4 5.5 3.8 1.2 8.6 25.5 0.0 0.0 4.9 13.4 12.3 0.0 30.0 1.3 7.6 3.3 8.7 1.8 3.0 1.8 19.2 5.6 8.6 8.2 16.3 4.5 0.9 7.5 9.6 15.3 0.0 1.3 3.5 12.2 24.8 35.1 1.1 0.9 35.9 16.0 1.0 29.0 1.6 5.2 1.5 2.9 42.2 10.7 0.0 3.5 13.0 8.5 2.9 12.9 0.3 0.0 12.3 9.8 1.7 2.3 18.2 48.4 31.3 8.2 1.4 5.0 33.3 SERPINF2 "A2AP, AAP, ALPHA-2-PI, API, PLI" ENSG00000167711 "Serpin family F member 2" P08697 17 1742836-1755265 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 1578.5" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1007.7" "Cancer enriched" "Detected in all" 6 "liver cancer: 450.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 44.7" "Lineage enriched" "Detected in many" 23 "dendritic cells: 44.7" "Cell line enriched" "Detected in some" 24 "Hep G2: 145.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001885, CAB024863" Approved "Secreted to blood" NA NA 11900 61000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB024863: , HPA001885: AB_1079922" "unprognostic (2.17e-3)" "unprognostic (2.56e-3)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (3.69e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.09e-3)" "unprognostic (7.05e-2)" "unprognostic (2.81e-1)" "unprognostic (7.68e-3)" "unprognostic (2.93e-1)" 11.6 2.0 1.4 4.3 1.5 0.4 18.3 1.2 2.2 7.1 11.1 4.2 0.7 8.7 101.4 3.0 19.6 0.7 2.5 2.0 1.4 74.1 1578.5 12.9 3.0 1.6 1.6 7.7 9.2 0.1 1.9 0.8 1.7 21.4 0.5 0.5 6.1 32.6 4.3 5.5 11.6 1.8 1.3 7.1 3.7 12.5 1.8 2.6 7.9 0.4 3.5 7.3 5.8 2.2 1.8 6.1 0.0 0.0 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.0 3.8 0.3 0.9 0.0 0.3 0.9 0.0 3.3 0.0 0.0 0.0 0.1 0.9 145.9 1.1 0.8 0.1 1.6 1.2 0.0 0.7 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.7 0.1 0.3 0.3 0.1 0.9 1.3 0.0 0.3 0.0 0.2 0.6 0.0 1.1 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.9 1.4 0.0 0.8 0.0 0.5 0.0 0.0 10.7 0.5 0.0 0.0 0.0 1.2 0.0 44.7 0.0 1.2 1.4 1.5 1.2 2.2 2.0 1.4 1.6 1.6 1.7 1.3 1.8 2.2 1.6 3.2 19.6 0.3 5.3 1.5 4.9 10.3 8.0 0.2 20.5 8.8 0.7 27.1 7.0 1.8 6.2 0.2 32.1 0.7 9.8 0.0 0.6 0.1 2.7 3.4 4.2 23.6 1.6 4.9 0.3 2.7 0.0 0.3 1.3 0.3 14.6 1007.7 7.7 0.0 1.9 2.1 12.2 32.2 20.1 0.8 33.8 8.2 1.8 1.0 10.9 0.1 0.0 1.0 0.7 3.8 2.7 26.7 3.2 2.8 2.2 87.5 4.4 0.4 0.0 1.3 1.2 0.4 0.5 1.3 1.6 0.3 2.6 0.0 3.3 1.8 SESN3 "MGC29667, SEST3" ENSG00000149212 "Sestrin 3" P58005 11 95165513-95232541 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 680.7;Late spermatids: 529.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 46.7;ASC TERT1: 50.7;SuSa: 110.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037935 Approved Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA037935: AB_10670534" "unprognostic (2.72e-2)" "unprognostic (3.06e-1)" "unprognostic (2.67e-1)" "unprognostic (8.09e-3)" "unprognostic (5.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.18e-1)" "unprognostic (8.19e-3)" "unprognostic (1.38e-1)" "unprognostic (3.78e-1)" "unprognostic (2.34e-3)" "unprognostic (4.43e-2)" "unprognostic (1.67e-3)" "unprognostic (1.69e-1)" "unprognostic (1.96e-1)" "unprognostic (1.76e-2)" "unprognostic (9.42e-2)" 9.6 17.5 42.3 14.3 56.4 17.9 14.7 24.3 37.8 11.8 26.0 5.7 6.5 11.4 14.1 8.9 8.4 12.4 5.4 32.6 30.7 10.5 7.5 9.1 24.4 21.4 40.6 21.9 3.1 25.8 11.2 7.1 22.5 10.2 6.5 23.4 9.9 5.5 5.3 10.7 12.5 9.2 28.8 17.3 4.9 57.7 54.6 21.8 21.7 13.1 24.2 11.2 8.8 26.6 0.0 1.0 28.2 0.1 46.7 50.7 0.1 0.2 0.0 0.0 0.1 1.2 0.9 7.7 3.4 0.1 1.3 5.7 17.3 12.5 0.0 6.4 9.0 3.9 15.4 1.2 0.9 3.4 0.7 28.1 21.4 0.1 6.3 8.7 1.1 4.5 0.4 1.4 2.3 0.2 2.5 9.0 11.5 0.2 1.2 5.7 1.7 0.6 6.2 19.1 3.6 7.9 0.3 0.2 1.6 110.9 0.0 11.0 0.3 3.2 7.1 0.6 1.1 0.3 0.0 1.0 1.4 4.0 6.9 0.5 0.3 0.2 0.2 0.7 0.3 1.8 0.8 0.5 0.3 1.1 1.6 0.6 0.3 0.3 1.5 0.4 1.7 0.3 42.3 56.4 24.3 37.8 32.6 30.7 21.4 40.6 22.5 28.8 54.6 26.6 13.4 25.6 7.9 152.8 97.6 23.1 26.2 38.3 76.2 48.2 16.1 25.5 7.6 2.8 15.6 35.0 22.9 0.7 7.1 6.9 1.9 6.0 680.7 7.7 45.4 36.4 7.3 73.4 130.8 2.3 0.6 36.5 10.7 14.5 7.0 28.0 35.3 6.4 23.4 0.0 95.1 11.4 8.2 54.8 58.8 529.5 40.7 36.7 32.0 97.4 82.0 98.9 10.3 48.2 37.2 2.2 7.3 87.3 11.9 13.6 27.7 22.5 4.5 14.8 6.6 31.5 28.9 45.4 11.1 38.2 12.5 1.6 41.3 76.4 14.8 14.9 SEZ6L ENSG00000100095 "Seizure related 6 homolog like" Q9BYH1 22 26169462-26383597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 60.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 222.1;Inhibitory neurons: 137.7;Oligodendrocyte precursor cells: 586.1" "Group enriched" "Detected in some" 6 "glioma: 14.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 5.9;myeloid DC: 5.7;non-classical monocyte: 5.3" "Group enriched" "Detected in many" 58 "dendritic cells: 5.7;monocytes: 5.9" "Group enriched" "Detected in some" 6 "SCLC-21H: 39.9;SH-SY5Y: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045135 Approved Vesicles NA NA 6700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA045135: AB_2732518" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (4.49e-2)" "unprognostic (6.47e-2)" "unprognostic (4.19e-1)" "unprognostic (1.09e-2)" "unprognostic (5.02e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-3)" "unprognostic (7.80e-2)" "unprognostic (2.40e-6)" "unprognostic (4.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.39e-4)" "unprognostic (3.18e-1)" 0.1 10.0 25.0 0.5 37.5 0.2 0.0 8.9 50.6 1.1 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 1.3 60.8 52.0 0.0 0.0 0.2 0.0 24.5 23.6 0.0 1.5 0.0 5.8 0.0 19.0 0.2 0.2 4.5 0.2 0.1 0.1 0.3 0.4 0.3 4.0 0.2 1.4 0.3 49.0 0.9 0.1 0.0 0.0 0.1 0.1 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.9 10.7 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 5.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.5 25.0 37.5 8.9 50.6 60.8 52.0 24.5 23.6 19.0 4.0 49.0 24.9 0.0 0.0 0.0 21.9 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.1 0.2 0.0 0.4 222.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.9 137.7 0.0 0.0 0.0 2.1 2.0 0.6 1.5 0.0 10.3 3.5 0.7 0.0 586.1 5.5 0.6 0.0 0.4 0.0 0.1 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 SF3B3 "KIAA0017, RSE1, SAP130, SF3b130" ENSG00000189091 "Splicing factor 3b subunit 3" Q15393 16 70523791-70577670 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041134, HPA042986" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No 50000 "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA041134: AB_2677317, HPA042986: AB_10960386" "unprognostic (3.39e-2)" "unprognostic (1.53e-1)" "unprognostic (7.47e-2)" "unprognostic (1.87e-1)" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (1.06e-2)" "unprognostic (7.67e-2)" "unprognostic (2.07e-1)" "unprognostic (2.29e-1)" "unprognostic (6.97e-2)" "unprognostic (2.29e-1)" "unprognostic (3.28e-2)" "unprognostic (1.60e-1)" "unprognostic (8.76e-2)" "unprognostic (7.91e-2)" "unprognostic (1.73e-1)" 15.7 11.2 7.9 19.2 8.2 22.2 13.8 15.9 9.6 16.3 11.4 17.1 13.6 17.0 10.2 19.9 16.4 11.6 12.1 8.8 9.7 12.5 12.3 11.7 24.3 7.0 6.9 22.3 13.8 16.8 7.9 14.1 7.5 11.6 13.2 16.3 12.6 10.7 23.6 19.9 12.9 16.0 6.5 13.9 13.2 10.2 10.4 23.7 14.5 11.7 26.6 14.2 14.4 12.0 72.4 72.6 93.4 65.3 45.5 41.6 74.0 66.3 55.5 84.5 67.3 75.6 55.8 97.1 52.6 51.8 49.9 81.4 98.0 55.7 133.0 31.5 71.1 75.1 56.7 81.0 30.6 106.1 83.9 39.8 40.1 93.9 68.8 54.1 50.9 55.3 104.6 34.2 67.4 87.5 92.9 51.6 85.2 44.8 41.9 163.2 73.3 109.7 26.9 96.4 81.4 59.8 217.7 33.8 33.8 39.2 73.9 53.0 52.7 61.9 67.8 49.2 71.6 37.4 90.4 260.7 40.9 66.9 61.3 23.4 26.1 28.1 35.8 30.8 39.3 28.4 33.1 37.5 35.3 34.3 38.8 33.7 8.3 35.5 31.2 19.1 40.2 37.4 7.9 8.2 15.9 9.6 8.8 9.7 7.0 6.9 7.5 6.5 10.4 12.0 18.9 25.6 25.7 16.6 33.0 22.4 23.2 23.4 13.1 35.5 20.5 18.3 29.3 14.3 25.4 23.9 14.6 33.6 21.6 19.7 7.9 20.7 6.3 17.8 31.9 25.4 21.1 36.8 23.2 23.2 34.7 24.2 20.4 17.5 17.7 52.3 17.5 23.6 23.6 40.4 26.5 21.8 24.4 20.6 12.8 10.3 33.8 19.2 17.8 24.4 22.7 19.4 25.7 26.2 26.7 24.9 14.0 33.1 25.1 30.2 18.1 15.7 18.8 26.7 6.6 30.2 18.8 28.7 33.3 37.6 26.1 25.4 28.3 48.2 31.6 24.7 SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261962-41309473 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 299.3;choroid plexus: 509.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 710.9;Breast myoepithelial cells: 1158.6;Cardiomyocytes: 266.3;Leydig cells: 578.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 3203.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008116, HPA064870" Approved Approved Nucleoli,Cytosol "Secreted in other tissues" Yes No 1300000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 35: Glandular cells - Unknown function" Nucleoli Cytosol "CAB008116: AB_2187070, HPA064870: AB_2685376" "unprognostic (1.23e-3)" "unprognostic (7.01e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-1)" "unprognostic (7.13e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.79e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.67e-3)" "unprognostic (3.52e-3)" "unprognostic (4.74e-2)" "unprognostic (1.72e-2)" "unprognostic (1.75e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (3.12e-4)" 88.4 12.9 9.2 10.5 12.7 1.4 299.3 18.2 15.0 203.7 509.2 24.5 12.2 132.5 1.8 26.1 98.5 61.3 124.8 29.4 8.5 115.3 6.1 4.7 4.0 29.9 10.5 46.8 6.2 1.4 1.2 19.5 29.7 42.6 30.1 2.2 236.9 102.3 2.6 55.4 18.9 82.9 7.7 21.4 24.4 28.4 10.8 3.1 12.7 32.8 3.2 44.9 95.6 24.7 0.1 29.0 75.9 1.9 67.5 3.9 14.5 132.9 694.5 197.9 187.2 0.0 17.8 0.0 0.6 0.7 15.8 0.9 10.8 53.7 277.6 0.0 2.3 0.0 0.0 0.0 6.4 0.0 0.7 11.8 255.9 19.9 19.3 3203.5 6.2 0.2 0.0 0.0 3.7 0.0 0.0 0.2 205.8 0.1 0.3 0.0 15.7 0.0 422.6 0.0 4.1 18.5 5.5 0.0 41.5 264.7 0.1 2.1 1.9 0.1 19.6 0.2 18.3 0.0 0.0 0.0 0.2 0.0 279.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.7 18.2 15.0 29.4 8.5 29.9 10.5 29.7 7.7 10.8 24.7 8.4 0.0 0.0 2.0 1.2 11.2 134.0 1.4 147.4 1.8 710.9 1158.6 266.3 0.0 0.7 62.5 2.1 2.2 9.1 0.0 80.3 4.4 5.0 3.0 131.6 21.0 0.0 0.0 0.2 0.0 82.0 229.5 16.8 3.4 0.0 19.3 53.6 0.3 2.0 1.7 12.1 0.0 0.0 0.3 4.0 25.7 578.4 4.0 99.6 0.0 0.0 76.2 0.0 7.5 20.6 0.1 0.0 130.1 2.1 29.7 0.0 3.2 0.0 1.8 0.0 34.9 18.0 2.3 16.8 53.7 5.5 0.8 7.3 72.6 0.0 9.3 SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 4 "Fibroblasts: 806.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "AF22: 229.1;ASC diff: 85.2;HSkMC: 140.2;NTERA-2: 318.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" 188.2 16.0 4.9 84.6 4.0 0.3 154.9 3.6 6.3 23.2 11.2 72.2 18.4 12.0 22.2 212.7 62.1 318.8 6.2 12.3 13.8 4.5 0.3 62.5 11.8 4.5 3.7 8.3 45.1 7.0 72.5 0.4 4.6 56.5 44.3 2.3 83.4 70.5 6.5 80.5 57.3 89.5 3.8 0.7 34.4 1.5 2.2 9.6 92.3 38.7 3.6 306.7 63.0 12.3 0.0 0.0 229.1 0.2 85.2 15.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 140.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 318.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.1 0.1 0.0 8.1 0.2 0.0 0.0 0.4 0.1 0.0 12.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.0 3.6 6.3 12.3 13.8 4.5 3.7 4.6 3.8 2.2 12.3 15.5 3.2 0.6 9.4 0.5 115.5 0.8 0.0 5.7 0.0 3.7 7.9 0.3 0.0 1.9 0.0 0.0 0.1 2.0 0.0 0.0 0.2 0.0 0.1 0.1 11.8 0.0 0.0 0.7 0.0 0.2 806.1 38.7 0.3 1.3 0.0 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.0 175.0 0.5 4.1 5.0 119.2 0.0 0.6 0.0 0.0 0.5 0.1 0.1 0.0 7.2 4.1 0.7 0.0 0.1 2.9 0.0 0.0 6.7 59.4 0.0 0.1 6.9 106.0 0.1 8.6 0.0 0.0 0.9 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SFTPD "COLEC7, SFTP4, SP-D" ENSG00000133661 "Surfactant protein D" P35247 10 79937467-79982614 "Predicted secreted proteins" "Gaseous exchange, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "lung: 507.9" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 2: 1863.1" "Cancer enriched" "Detected in many" 16 "lung cancer: 106.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 10.0;non-classical monocyte: 36.3" "Lineage enriched" "Detected in many" 18 "monocytes: 36.3" "Cell line enhanced" "Detected in some" "BEWO: 1.1;HaCaT: 1.0;hTCEpi: 3.2;MCF7: 1.3;U-2197: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB004578, HPA044582, HPA056768" Enhanced "Secreted in other tissues" NA NA 8200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "CAB004578: AB_628276, HPA044582: AB_2679004, HPA056768: AB_2683232" "unprognostic (3.81e-5)" "unprognostic (7.00e-2)" "unprognostic (1.19e-2)" "unprognostic (1.41e-2)" "unprognostic (4.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.66e-3)" "unprognostic (6.83e-2)" "unprognostic (3.85e-1)" "unprognostic (2.23e-1)" "unprognostic (5.29e-2)" "unprognostic (2.57e-1)" "unprognostic (4.70e-2)" "unprognostic (2.57e-2)" "unprognostic (2.38e-1)" "unprognostic (1.45e-1)" "unprognostic (8.86e-2)" 1.1 1.8 2.2 0.4 2.4 19.7 0.9 1.7 2.5 1.3 2.3 1.0 0.1 0.5 1.3 1.8 1.8 0.9 1.1 2.2 2.4 1.6 1.0 507.9 0.0 1.7 2.0 1.1 4.2 2.0 3.4 0.7 1.8 1.4 0.1 0.3 1.0 1.2 0.2 5.0 0.4 0.4 1.4 0.6 1.1 1.3 2.6 0.5 5.8 0.2 0.2 0.3 2.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.8 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.1 0.3 0.3 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 10.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 36.3 0.0 0.0 0.9 2.2 2.4 1.7 2.5 2.2 2.4 1.7 2.0 1.8 1.4 2.6 1.7 0.3 439.1 1863.1 1.0 0.2 0.9 1.3 7.8 1.2 1.7 1.4 1.8 0.7 0.0 38.0 5.5 0.0 0.1 0.0 0.0 1.9 1.4 7.4 0.6 0.1 1.5 0.0 0.0 4.9 5.8 3.0 4.4 0.0 0.9 20.2 1.6 0.4 0.7 0.1 0.0 3.5 0.0 0.0 0.0 2.7 12.2 1.2 2.9 0.0 1.9 0.6 2.8 0.0 0.0 0.6 2.0 0.1 0.4 0.0 0.8 0.0 0.2 9.6 0.5 0.0 1.8 0.4 0.4 0.3 0.6 1.8 0.1 4.3 0.1 0.1 0.6 SGCA "A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1" ENSG00000108823 "Sarcoglycan alpha" Q16586 17 50164214-50175928 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 155.6;skeletal muscle: 522.4;tongue: 237.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 128.4;Early spermatids: 162.6;Late spermatids: 705.4;Skeletal myocytes: 195.2" "Cancer enhanced" "Detected in many" "prostate cancer: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 1.4;memory B-cell: 3.3;myeloid DC: 2.2;naive B-cell: 3.3;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 15 "B-cells: 3.3;dendritic cells: 2.2;monocytes: 1.8" "Cell line enriched" "Detected in some" 16 "LHCN-M2: 78.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007537 Uncertain "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA007537: AB_1079944" "unprognostic (1.34e-1)" "unprognostic (2.30e-2)" "unprognostic (1.89e-3)" "unprognostic (1.25e-1)" "unprognostic (9.87e-2)" "unprognostic (2.43e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-2)" "unprognostic (1.15e-1)" "unprognostic (1.91e-1)" "unprognostic (7.01e-2)" "unprognostic (2.57e-1)" "unprognostic (2.07e-3)" "unprognostic (4.96e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-1)" "unprognostic (1.15e-2)" 12.2 1.5 1.8 7.3 2.9 0.0 4.3 3.5 2.2 10.1 1.0 53.7 5.3 36.9 1.6 22.8 18.1 11.9 155.6 1.4 1.5 2.7 4.8 29.7 0.5 1.6 1.5 5.1 1.3 0.8 0.9 6.7 1.8 26.0 3.2 0.1 8.7 27.1 522.4 12.4 14.8 23.0 1.1 3.4 24.1 1.7 1.7 2.3 3.4 237.0 0.4 46.5 11.6 4.7 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.1 0.0 1.4 0.0 3.3 0.0 0.0 2.2 3.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.4 1.8 2.9 3.5 2.2 1.4 1.5 1.6 1.5 1.8 1.1 1.7 4.7 1.1 0.0 0.0 0.0 1.3 8.7 0.5 0.4 0.0 0.6 0.1 0.5 128.4 0.0 0.3 0.0 0.0 0.5 1.4 0.0 0.0 0.6 162.6 0.0 0.2 4.6 0.0 0.0 0.0 5.8 0.1 30.4 0.5 0.0 0.0 0.0 2.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 16.5 705.4 3.1 0.8 8.8 1.9 1.9 0.0 0.0 0.0 0.1 4.1 0.0 3.8 0.1 0.6 0.0 2.1 0.0 0.0 13.1 195.2 48.2 2.3 1.9 0.1 9.9 0.3 0.9 0.0 0.0 0.2 SGCD "CMD1L, DAGD, LGMD2F" ENSG00000170624 "Sarcoglycan delta" Q92629 5 155870344-156767788 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 39.1;skeletal muscle: 42.9;tongue: 33.3" "Group enriched" "Detected in many" 4 "Astrocytes: 365.7;Cardiomyocytes: 107.8;Excitatory neurons: 193.0;Inhibitory neurons: 161.2;Microglial cells: 124.6;Oligodendrocyte precursor cells: 417.2;Oligodendrocytes: 196.4" "Cancer enriched" "Detected in many" 5 "melanoma: 10.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 16.1;fHDF/TERT166: 25.7;LHCN-M2: 12.7;RH-30: 18.2;SK-MEL-30: 27.0;U-138 MG: 24.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (2.23e-1)" "unprognostic (3.82e-2)" "unprognostic (9.11e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (9.55e-2)" "unprognostic (2.63e-1)" "unprognostic (1.66e-1)" "unprognostic (6.53e-2)" "unprognostic (2.25e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-2)" "unprognostic (4.10e-2)" "unprognostic (9.65e-3)" "unprognostic (5.37e-2)" "unprognostic (5.60e-3)" "unprognostic (3.66e-3)" 5.4 4.2 3.2 2.1 2.0 0.0 3.3 1.6 3.6 6.8 0.0 7.9 2.0 8.2 2.5 6.2 2.9 9.3 39.1 2.9 2.7 1.3 2.0 5.0 0.4 4.2 3.8 8.8 1.0 9.9 1.5 0.6 4.3 6.0 3.6 1.6 1.9 5.2 42.9 1.6 2.7 13.4 3.9 1.4 2.9 1.3 2.0 0.7 17.8 33.3 0.5 6.6 3.1 6.6 0.0 6.4 0.0 0.0 5.8 9.2 0.0 16.1 5.5 0.0 0.2 0.0 0.0 0.0 0.0 25.7 0.0 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 8.5 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 3.0 0.1 0.0 0.0 27.0 0.0 0.0 0.0 0.0 24.1 0.0 4.3 0.0 0.1 0.1 0.0 4.1 0.0 9.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.0 1.6 3.6 2.9 2.7 4.2 3.8 4.3 3.9 2.0 6.6 0.7 0.0 0.5 365.7 0.0 3.6 0.0 0.0 0.0 3.5 4.0 2.2 107.8 0.0 0.0 0.0 54.2 0.0 1.6 0.1 0.0 0.1 6.9 6.1 1.5 1.7 1.8 0.0 193.0 0.0 0.0 27.4 0.0 16.3 0.0 11.3 3.3 1.6 0.2 21.9 161.2 0.0 0.0 0.0 2.5 13.3 19.0 0.8 24.9 124.6 0.0 0.3 0.0 417.2 196.4 0.0 0.0 15.4 0.7 0.8 0.0 0.3 0.0 1.2 0.0 38.5 5.9 0.0 0.4 0.5 3.1 0.1 1.0 9.4 0.0 0.2 SGIP1 DKFZp761D221 ENSG00000118473 "SH3GL interacting endocytic adaptor 1" Q9BQI5 1 66533383-66751139 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "retina: 131.4" "Group enriched" "Detected in many" 4 "Astrocytes: 390.1;Cone photoreceptor cells: 350.3;Excitatory neurons: 323.3;Inhibitory neurons: 401.5;Oligodendrocyte precursor cells: 482.0;Oligodendrocytes: 363.6;Rod photoreceptor cells: 344.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 29.9;BJ hTERT+: 38.0;fHDF/TERT166: 24.5;hTERT-RPE1: 15.8;RPTEC TERT1: 27.5;SH-SY5Y: 15.3;U-138 MG: 27.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017963 Approved Approved Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Mitochondria "HPA017963: AB_10964882" "unprognostic (1.74e-2)" "unprognostic (2.77e-1)" "unprognostic (2.86e-1)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" "unprognostic (9.04e-2)" "unprognostic (9.51e-2)" "unprognostic (7.64e-2)" "unprognostic (1.86e-1)" "unprognostic (1.61e-1)" "unprognostic (1.83e-1)" "unprognostic (1.95e-1)" "unprognostic (3.48e-7)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (4.25e-2)" "unprognostic (9.63e-2)" 7.4 4.3 12.2 1.9 15.5 0.2 2.7 6.3 17.4 10.4 0.0 3.1 1.6 10.6 4.6 2.7 3.8 4.6 5.0 15.3 5.8 18.0 0.7 8.3 0.7 5.1 5.7 1.6 0.5 0.2 7.7 1.9 5.3 5.8 1.5 131.4 1.7 5.0 2.5 1.6 2.0 3.8 1.6 0.3 3.3 4.4 5.5 0.7 8.9 1.2 0.4 2.7 5.4 10.1 0.0 0.0 0.0 0.0 0.9 5.5 0.0 29.9 38.0 2.3 3.4 0.0 0.0 0.0 0.1 24.5 0.2 0.0 0.0 0.1 4.3 0.0 0.0 1.1 0.4 0.0 6.5 0.0 0.0 4.1 0.0 2.3 0.0 15.8 11.3 0.2 0.0 0.0 13.8 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.1 27.5 0.0 0.7 15.3 0.0 0.0 0.0 0.6 0.0 1.1 1.9 27.3 0.0 0.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 15.5 6.3 17.4 15.3 5.8 5.1 5.7 5.3 1.6 5.5 10.1 5.0 0.0 0.0 390.1 0.1 1.0 0.3 0.4 0.0 89.8 0.2 4.7 2.5 2.8 0.0 9.2 350.3 0.1 0.0 0.1 7.9 0.5 0.6 2.9 7.8 13.8 0.0 0.0 323.3 0.0 0.0 15.8 0.5 5.7 10.1 0.0 0.4 0.2 0.2 74.0 401.5 0.0 0.0 0.0 1.1 1.2 2.1 0.4 10.6 48.7 0.0 49.4 0.0 482.0 363.6 0.0 0.0 11.3 0.8 0.8 0.0 0.2 0.0 344.1 13.1 3.2 32.2 0.2 0.4 0.1 1.0 0.3 0.5 0.0 0.1 0.3 SGK2 ENSG00000101049 "Serum/glucocorticoid regulated kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.5;kidney: 53.6;liver: 63.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.5;Distal tubular cells: 76.3;Hepatocytes: 32.8;Paneth cells: 21.7;Proximal enterocytes: 23.8;Proximal tubular cells: 25.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 20.5;CAPAN-2: 14.2;Hep G2: 18.7;OE19: 61.7;RPTEC TERT1: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA008859: AB_2668159, HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favorable (5.65e-4)" 23.5 1.4 4.9 1.5 14.8 0.5 6.1 12.6 10.5 3.5 0.7 37.7 31.6 1.8 33.8 1.0 3.7 10.0 1.2 6.0 7.7 53.6 63.2 1.0 0.2 18.1 13.3 6.6 16.2 0.5 3.0 0.8 14.3 2.6 40.5 5.6 1.8 2.9 0.4 6.2 20.1 1.6 11.8 1.1 22.8 1.8 13.3 0.3 1.7 0.4 0.3 4.2 3.0 24.5 0.0 20.5 0.3 0.1 0.3 0.0 0.1 0.2 0.0 0.2 0.0 0.6 14.2 0.1 8.7 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.4 0.0 18.7 0.4 0.0 0.1 0.0 0.5 0.0 0.0 0.7 0.0 0.4 0.2 0.1 0.0 0.1 0.1 0.5 0.1 61.7 0.0 0.1 0.1 0.0 25.4 4.2 0.2 1.0 0.0 1.2 0.1 0.4 0.0 0.1 0.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 14.8 12.6 10.5 6.0 7.7 18.1 13.3 14.3 11.8 13.3 24.5 0.3 0.0 0.0 4.9 0.2 0.1 0.1 0.2 0.0 0.8 0.3 0.8 4.9 8.6 0.0 11.0 0.0 5.1 0.0 76.5 76.3 6.8 0.3 0.9 0.5 0.6 1.8 0.0 0.7 6.3 1.3 0.4 11.2 2.4 0.0 0.7 0.7 32.8 0.7 6.7 1.3 4.1 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 3.5 20.7 2.5 21.7 0.4 0.0 0.1 23.8 25.5 0.2 0.8 0.0 0.2 0.4 0.1 0.1 0.0 0.1 17.1 0.2 0.0 7.7 0.3 SGMS1 "MGC17342, MOB, SMS1, TMEM23" ENSG00000198964 "Sphingomyelin synthase 1" Q86VZ5 10 50305586-50625163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.1;Microglial cells: 229.5;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 422.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045191 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA045191: AB_10959605" "unprognostic (1.13e-1)" "unprognostic (5.75e-2)" "unprognostic (1.87e-1)" "unprognostic (9.08e-2)" "unprognostic (8.69e-3)" "unprognostic (8.34e-2)" "unprognostic (7.98e-2)" "unprognostic (2.29e-1)" "unprognostic (1.30e-2)" "unprognostic (5.75e-2)" "unprognostic (9.20e-2)" "unprognostic (2.05e-1)" "prognostic favorable (1.95e-7)" "unprognostic (8.38e-2)" "unprognostic (1.95e-1)" "unprognostic (3.31e-1)" "unprognostic (3.05e-1)" 15.8 19.3 19.8 10.7 27.4 24.0 14.5 21.5 20.3 16.9 33.9 10.1 13.5 11.9 19.9 15.3 16.6 15.4 13.2 17.2 23.0 20.2 27.9 21.9 14.9 29.5 24.1 18.6 13.3 52.9 6.4 24.6 28.5 19.5 11.7 20.2 18.0 16.8 9.9 25.3 16.0 15.8 23.6 11.7 14.3 11.3 23.4 12.0 24.7 10.5 14.5 20.9 13.1 41.3 30.2 14.0 4.0 9.0 14.2 18.6 18.8 19.6 19.7 13.5 12.6 11.7 30.3 22.1 11.3 25.9 12.2 18.7 9.5 20.6 14.0 19.4 10.2 32.7 17.9 9.0 16.5 7.5 7.6 12.1 23.6 18.0 21.7 8.7 19.3 7.9 62.6 32.2 14.6 12.7 3.3 4.2 9.2 13.7 13.7 5.5 18.4 8.8 19.7 31.2 6.2 4.9 14.4 14.2 7.5 11.3 21.4 2.7 27.1 14.6 17.8 14.1 14.6 11.0 9.5 6.3 18.2 12.0 12.1 3.4 9.3 28.4 4.6 4.9 10.3 7.0 6.2 6.8 5.2 6.5 8.2 5.4 16.7 10.1 4.0 3.2 15.6 6.3 19.8 27.4 21.5 20.3 17.2 23.0 29.5 24.1 28.5 23.6 23.4 41.3 17.1 44.8 40.0 106.7 19.9 54.4 28.9 15.6 23.9 20.1 15.8 8.9 26.3 10.0 30.0 29.5 4.2 10.9 15.6 6.2 15.6 17.6 17.0 20.9 10.5 19.6 14.9 32.0 153.1 21.6 7.7 19.8 30.5 32.4 20.8 12.1 17.9 16.0 29.0 5.0 117.2 11.1 4.1 46.5 17.6 30.6 16.1 34.5 12.4 229.5 12.4 17.4 10.3 313.1 422.0 10.7 6.4 10.5 13.7 32.3 18.4 9.3 25.1 36.4 0.0 20.5 27.1 12.8 2.3 18.7 83.4 4.9 20.0 11.8 12.4 25.4 SGO1 "NY-BR-85, SGOL1" ENSG00000129810 "Shugoshin 1" Q5FBB7 3 20160593-20186206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;lymphoid tissue: 13.0;testis: 6.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 16.5;Extravillous trophoblasts: 42.6;Granulosa cells: 20.3;Hofbauer cells: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "basophil: 10.0;memory B-cell: 8.8;naive B-cell: 8.9;plasmacytoid DC: 4.1;T-reg: 2.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035501, HPA069302, HPA069857" Enhanced Enhanced Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Kinetochore, Cytosol" "HPA035501: AB_2732469, HPA069302: , HPA069857: AB_2686214" "unprognostic (6.87e-3)" "unprognostic (5.01e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-3)" "unprognostic (2.51e-2)" "unprognostic (4.10e-2)" "unprognostic (2.55e-6)" "unprognostic (9.49e-3)" "unprognostic (2.45e-2)" "unprognostic (3.69e-2)" "unprognostic (1.65e-4)" "unprognostic (1.52e-2)" "unprognostic (0.00e+0)" "unprognostic (2.29e-2)" "unprognostic (4.95e-2)" "unprognostic (4.14e-1)" "unprognostic (1.64e-1)" 0.3 0.1 0.3 3.3 0.7 8.7 0.5 0.9 0.5 0.4 0.0 2.1 2.3 0.4 0.0 1.9 0.1 0.4 0.1 0.3 0.4 0.3 0.6 0.3 6.2 0.8 0.6 0.2 0.1 0.2 0.0 1.7 0.6 0.2 2.8 0.1 0.4 0.1 0.1 1.1 2.5 1.0 0.3 1.4 1.5 6.7 0.6 13.0 0.2 0.0 6.6 0.9 0.7 1.2 20.3 23.9 29.9 18.5 1.4 2.6 20.2 21.3 10.1 31.2 33.6 16.5 24.0 30.7 10.6 8.6 21.2 11.4 28.7 11.3 37.6 40.9 19.6 34.6 15.6 12.8 0.2 32.0 28.8 0.3 0.9 33.3 13.1 4.0 18.5 34.9 31.3 52.2 24.6 19.4 52.4 15.4 30.0 20.3 17.0 31.8 38.4 17.7 7.5 14.9 14.2 15.4 23.6 27.2 13.1 22.7 18.2 21.3 4.7 22.5 27.3 20.5 43.3 22.8 57.4 35.2 12.5 31.1 35.0 10.0 0.1 1.4 0.2 0.2 0.1 8.8 0.6 0.7 0.3 8.9 0.2 0.3 1.4 0.3 0.2 4.1 2.6 0.6 0.3 0.7 0.9 0.5 0.3 0.4 0.8 0.6 0.6 0.3 0.6 1.2 0.1 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 2.0 3.4 0.0 0.0 0.0 1.8 0.0 16.5 1.5 0.0 0.0 1.1 0.0 2.3 1.6 1.2 0.0 0.0 0.0 1.8 42.6 3.3 0.0 2.9 1.3 20.3 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 4.9 1.0 4.3 0.0 0.0 SGO2 "FLJ25211, SGOL2, TRIPIN" ENSG00000163535 "Shugoshin 2" Q562F6 2 200510008-200584096 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.9;testis: 32.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.6;Endometrial ciliated cells: 12.1;Extravillous trophoblasts: 31.0;granulocytes: 11.4;Granulosa cells: 23.4;Hofbauer cells: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035163, HPA040817" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA035163: AB_10602397, HPA040817: AB_2677149" "unprognostic (3.43e-1)" "unprognostic (1.70e-1)" "unprognostic (7.06e-3)" "unprognostic (6.71e-3)" "unprognostic (1.90e-1)" "unprognostic (1.77e-1)" "unprognostic (7.55e-6)" "unprognostic (1.12e-2)" "unprognostic (1.98e-3)" "unprognostic (4.87e-2)" "unprognostic (1.37e-4)" "unprognostic (9.49e-2)" "unprognostic (8.07e-9)" "unprognostic (5.21e-2)" "unprognostic (5.43e-2)" "unprognostic (9.86e-2)" "unprognostic (2.02e-1)" 3.3 0.9 0.6 4.4 0.9 6.8 1.9 0.8 0.9 0.9 0.3 3.1 2.5 1.8 0.7 2.4 1.4 1.2 1.0 0.5 0.9 0.9 0.8 1.5 7.9 0.9 0.9 1.9 0.5 1.1 0.3 2.6 0.9 1.4 3.2 0.9 0.7 0.7 0.4 2.3 2.6 2.0 0.7 2.0 1.8 32.6 0.9 14.9 1.2 0.6 8.1 1.5 0.9 1.2 34.6 16.2 37.0 17.4 5.2 7.9 23.7 38.7 16.6 32.0 33.1 24.3 23.5 22.5 18.6 18.1 34.4 25.3 33.6 20.1 54.5 48.0 16.9 43.5 21.6 17.5 1.6 43.9 33.1 3.4 2.5 32.9 17.3 8.0 29.4 31.3 33.1 31.6 61.4 15.4 35.9 17.9 26.7 24.9 41.2 28.8 49.1 21.3 13.3 13.6 22.2 15.4 28.6 13.3 16.3 29.2 14.1 25.2 18.1 33.9 34.0 31.6 34.0 14.3 33.5 49.8 21.4 28.9 49.4 16.7 1.4 4.5 2.2 1.4 1.4 2.7 2.4 2.2 0.8 3.2 1.8 2.2 1.0 2.0 1.7 1.7 3.6 1.2 0.6 0.9 0.8 0.9 0.5 0.9 0.9 0.9 0.9 0.7 0.9 1.2 9.4 3.2 3.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 5.8 7.1 0.0 0.0 6.2 0.0 0.0 11.6 7.8 0.0 3.9 3.9 0.0 12.1 5.3 3.3 0.0 0.0 0.0 2.7 31.0 6.7 0.0 3.6 11.4 23.4 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.0 1.7 0.0 0.0 2.5 8.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 3.4 3.8 4.0 0.0 0.0 SGPL1 SPL ENSG00000166224 "Sphingosine-1-phosphate lyase 1" O95470 10 70815948-70881184 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 112.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021125, HPA023086" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "HPA021125: AB_1856803, HPA023086: AB_1856804" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (7.60e-2)" "unprognostic (2.98e-2)" "unprognostic (2.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (2.12e-1)" "unprognostic (9.52e-2)" "unprognostic (3.42e-1)" "unprognostic (2.14e-1)" "unprognostic (9.21e-2)" "unprognostic (4.68e-3)" 12.0 12.7 15.8 18.0 17.4 6.8 13.0 15.2 16.3 17.6 11.0 16.7 16.0 14.4 18.8 27.9 15.3 12.6 6.4 14.7 16.4 15.5 22.9 10.7 18.1 18.6 16.7 9.0 18.5 21.0 9.4 10.0 17.4 17.5 17.9 10.8 14.3 12.4 9.6 30.4 22.8 13.9 17.4 16.1 12.3 14.0 17.7 17.9 20.1 6.0 20.1 25.0 14.7 19.8 26.9 35.2 33.2 38.1 8.9 11.5 22.1 15.5 16.4 16.5 21.4 38.4 57.8 24.2 18.0 15.8 15.9 44.1 28.8 31.0 23.5 39.1 15.6 2.5 17.5 46.2 33.6 10.6 20.9 21.8 51.4 22.1 57.6 34.6 10.4 22.3 7.2 20.4 23.6 29.6 13.2 7.1 15.0 35.4 19.5 16.6 25.2 9.1 26.3 112.1 22.6 27.5 30.9 46.6 28.5 25.9 24.3 7.5 20.3 14.8 38.7 11.6 30.1 8.4 12.6 11.0 14.7 19.3 10.7 1.1 18.2 14.0 18.0 34.6 16.5 7.2 11.5 14.7 16.2 8.7 8.5 13.5 15.0 18.8 44.9 8.9 11.8 12.4 15.8 17.4 15.2 16.3 14.7 16.4 18.6 16.7 17.4 17.4 17.7 19.8 3.8 16.0 6.4 32.3 11.0 12.2 17.8 21.4 8.0 6.3 15.8 9.8 6.3 27.1 23.2 46.0 20.9 7.3 16.0 41.5 3.9 36.2 2.9 30.2 13.3 7.3 25.1 4.4 48.7 37.6 13.8 10.1 6.6 46.1 14.7 23.1 7.1 44.5 27.6 15.2 38.8 21.2 22.4 43.1 16.1 5.2 11.5 25.7 7.2 35.6 22.7 9.8 25.7 41.7 43.8 55.6 18.8 20.3 5.9 26.0 53.5 12.0 26.6 9.7 6.6 13.3 19.0 20.0 34.0 15.9 22.7 6.3 11.1 18.2 20.9 25.3 SGPP1 ENSG00000126821 "Sphingosine-1-phosphate phosphatase 1" Q9BX95 14 63684216-63728065 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 61.8;Oligodendrocytes: 60.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 43.8;U-698: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053149, HPA064908" Approved Supported Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA053149: AB_2682057, HPA064908: AB_2797270" "unprognostic (1.57e-2)" "unprognostic (1.04e-2)" "unprognostic (5.40e-3)" "unprognostic (7.82e-2)" "unprognostic (9.09e-2)" "unprognostic (4.30e-2)" "unprognostic (6.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.64e-1)" "unprognostic (7.41e-2)" "unprognostic (1.51e-1)" "unprognostic (3.27e-1)" "unprognostic (8.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-3)" 7.9 10.6 5.3 6.0 6.0 3.0 6.4 5.8 7.9 6.4 3.6 7.0 3.8 7.4 6.2 4.9 5.7 5.5 4.9 5.3 5.9 15.9 19.5 6.9 13.3 6.6 6.2 5.8 12.7 10.2 5.6 12.0 6.6 7.4 5.3 4.1 4.8 4.0 4.2 3.8 8.8 4.8 7.3 9.3 5.5 5.4 5.8 5.8 5.8 2.6 12.9 5.8 6.8 8.0 19.7 6.2 3.0 8.6 10.7 9.9 35.9 15.7 10.9 9.6 10.7 2.7 10.9 43.8 4.5 8.0 8.0 20.3 4.8 9.3 15.3 17.3 5.7 4.0 3.4 4.4 13.1 7.3 12.2 7.3 14.7 8.4 13.2 9.7 4.6 8.2 2.3 1.2 14.1 7.3 8.6 0.1 2.1 3.2 13.1 2.1 8.4 3.5 15.2 9.7 1.8 5.0 11.0 10.2 8.4 9.2 13.3 2.6 5.2 13.2 9.1 9.5 7.9 10.1 6.5 57.4 9.7 0.0 5.8 6.9 0.2 1.7 0.5 1.4 0.5 1.8 0.5 0.3 0.3 0.4 0.8 0.6 0.2 0.3 2.1 0.1 1.3 0.3 5.3 6.0 5.8 7.9 5.3 5.9 6.6 6.2 6.6 7.3 5.8 8.0 5.3 12.8 16.2 22.2 22.6 9.7 6.1 4.1 8.0 4.0 9.4 5.2 3.8 24.3 3.2 51.5 0.0 23.4 10.9 11.9 0.0 6.0 2.4 6.3 12.1 6.5 18.6 9.7 32.6 9.1 27.0 12.8 3.1 10.1 11.4 5.0 6.1 43.6 23.7 10.1 38.5 10.2 2.0 61.8 20.1 1.2 6.2 18.6 17.8 21.5 6.8 8.2 2.1 31.7 60.0 13.2 13.5 17.0 5.7 8.1 3.2 22.7 2.6 5.4 6.6 8.1 11.3 7.4 3.5 4.6 13.5 33.0 10.4 10.3 10.3 5.6 SH2D1A "DSHP, EBVS, IMD5, LYP, MTCP1, SAP, XLP, XLPD" ENSG00000183918 "SH2 domain containing 1A" O60880 X 124227868-124373197 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "lymphoid tissue: 262.5" "Group enriched" "Detected in some" 7 "dendritic cells: 77.6;NK-cells: 138.0;T-cells: 108.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 54 "gdT-cell: 120.2;MAIT T-cell: 162.9;memory CD4 T-cell: 90.4;memory CD8 T-cell: 175.8;naive CD4 T-cell: 91.2;naive CD8 T-cell: 108.3;NK-cell: 162.2;T-reg: 125.3" "Group enriched" "Detected in many" 70 "NK-cells: 162.2;T-cells: 175.8" "Group enriched" "Detected in some" 6 "HDLM-2: 101.1;JURKAT: 193.0;Karpas-707: 201.3;MOLT-4: 257.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072265 Approved Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA072265: " "prognostic favorable (2.03e-4)" "unprognostic (1.18e-3)" "unprognostic (4.35e-3)" "unprognostic (9.66e-5)" "unprognostic (1.60e-1)" "unprognostic (1.86e-3)" "unprognostic (9.25e-3)" "unprognostic (3.34e-2)" "unprognostic (1.88e-2)" "unprognostic (2.80e-3)" "unprognostic (9.33e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.94e-6)" "unprognostic (1.27e-1)" "unprognostic (9.00e-2)" "unprognostic (2.36e-1)" "unprognostic (3.14e-3)" 1.4 1.1 0.0 10.8 0.1 5.4 1.2 0.1 0.2 0.9 0.1 1.6 1.5 0.6 0.6 1.1 0.5 4.1 0.3 0.1 0.1 0.4 2.8 3.2 38.4 0.2 0.1 0.4 0.2 0.2 0.2 0.3 0.1 1.1 1.5 0.0 1.3 0.3 0.3 0.4 2.5 0.6 0.2 14.7 2.7 0.2 0.1 262.5 0.7 1.2 16.6 5.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 101.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 193.0 0.0 201.3 0.0 0.0 257.2 4.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 32.7 33.3 0.0 0.2 0.0 0.0 1.4 0.6 0.1 120.2 0.5 162.9 1.1 90.4 175.8 0.5 0.2 91.2 108.3 2.4 162.2 1.2 0.8 125.3 91.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 1.1 3.2 4.7 0.0 3.0 1.5 0.1 0.0 0.0 0.0 0.7 0.8 0.2 1.5 0.0 0.0 0.0 0.1 77.6 0.0 0.0 0.0 0.0 0.5 0.2 0.7 0.0 7.4 0.1 0.0 0.0 2.0 1.1 0.2 3.8 0.0 3.6 0.9 0.1 0.0 0.0 0.0 0.0 5.6 4.4 0.0 0.0 4.3 5.4 0.0 2.3 0.0 138.0 0.5 0.2 0.0 0.0 0.0 14.1 0.2 0.0 0.5 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.2 1.0 0.1 108.9 0.0 0.0 0.0 SH2D2A "F2771, TSAd" ENSG00000027869 "SH2 domain containing 2A" Q9NP31 1 156806243-156816848 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 33.9;dendritic cells: 139.5;NK-cells: 113.3;T-cells: 103.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 30 "NK-cells: 28.5;T-cells: 66.5" "Cell line enhanced" "Detected in many" "HDLM-2: 46.5;HMC-1: 33.3;Karpas-707: 81.0;RPMI-8226: 24.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.5;hippocampal formation: 1.6" HPA074482 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA074482: " "prognostic favorable (4.96e-4)" "unprognostic (2.76e-2)" "unprognostic (7.50e-2)" "unprognostic (3.03e-3)" "unprognostic (1.14e-3)" "unprognostic (2.73e-1)" "unprognostic (3.11e-1)" "unprognostic (9.80e-2)" "unprognostic (3.08e-1)" "unprognostic (1.64e-1)" "unprognostic (9.34e-3)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.26e-12)" "unprognostic (1.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.79e-1)" "prognostic favorable (1.31e-4)" 3.5 0.9 1.0 11.4 1.1 4.3 1.3 3.8 1.6 1.8 1.9 2.2 2.5 1.7 0.3 1.2 1.5 3.3 2.5 0.9 1.5 2.5 2.2 5.4 9.4 1.9 1.1 0.6 1.0 0.3 1.8 0.8 1.5 2.5 2.0 3.4 0.9 0.7 0.4 0.4 5.4 1.6 1.2 13.0 2.9 0.3 1.1 14.9 1.6 0.0 5.9 3.7 1.2 1.3 2.6 0.4 0.0 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 1.7 2.4 0.0 6.8 0.0 0.0 0.0 0.4 1.3 0.1 46.5 0.1 6.8 0.5 0.9 0.2 0.4 33.3 0.5 0.0 0.2 3.3 0.0 0.3 11.8 1.9 81.0 0.0 0.2 5.9 0.7 4.9 4.1 8.3 0.9 0.0 24.5 0.1 0.3 7.5 0.0 1.6 0.9 0.8 0.5 0.2 1.3 2.2 0.0 0.0 0.3 0.5 11.6 16.6 8.3 0.0 6.9 0.2 1.0 0.1 0.0 66.5 0.0 61.8 1.1 27.6 40.8 0.1 0.3 10.4 27.2 1.5 28.5 0.2 0.1 34.1 18.6 1.0 1.1 3.8 1.6 0.9 1.5 1.9 1.1 1.5 1.2 1.1 1.3 1.2 3.2 2.3 0.0 4.6 2.2 0.3 0.4 1.2 33.9 1.0 1.9 0.9 0.0 1.3 0.0 0.0 0.1 139.5 1.2 0.0 0.3 0.2 0.2 2.5 0.6 1.2 6.1 0.0 0.6 1.0 4.8 9.2 0.5 8.2 0.3 1.8 0.9 1.1 0.0 0.0 0.9 0.0 1.9 2.1 0.0 0.0 4.1 0.0 1.9 1.1 1.3 113.3 0.0 0.5 6.1 1.4 0.0 24.2 0.5 0.3 0.2 0.7 1.6 0.0 0.5 2.9 0.1 4.9 3.0 1.3 0.1 103.2 0.1 1.8 0.5 SH3BP1 ARHGAP43 ENSG00000100092 "SH3 domain binding protein 1" Q9Y3L3 22 37634654-37656117 "Metabolic proteins, Predicted intracellular proteins" Phagocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 43.5;HMC-1: 45.4;NB-4: 44.7" "Low region specificity" "Detected in all" HPA000757 Supported Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA000757: AB_1079951" "unprognostic (7.81e-3)" "unprognostic (7.91e-3)" "unprognostic (3.42e-1)" "unprognostic (2.62e-2)" "unprognostic (5.38e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.55e-4)" "unprognostic (1.39e-1)" "unprognostic (3.08e-1)" "unprognostic (1.89e-1)" "unprognostic (2.59e-2)" "unprognostic (4.78e-1)" "prognostic unfavorable (3.48e-7)" "prognostic favorable (3.39e-4)" "unprognostic (1.74e-1)" "unprognostic (5.37e-2)" "unprognostic (8.48e-3)" 4.2 3.6 3.4 14.2 3.4 14.4 3.4 3.7 6.2 12.2 2.7 19.4 18.1 3.2 0.7 37.7 4.0 2.1 2.0 4.1 4.5 3.2 2.6 8.8 12.1 6.0 3.9 3.4 2.8 2.2 2.1 5.1 4.7 7.6 4.5 0.2 9.3 2.0 0.7 27.0 20.9 2.0 4.8 27.0 4.3 5.7 4.7 8.2 2.5 0.5 7.7 10.5 21.1 5.7 20.1 1.0 3.9 3.4 0.9 3.9 28.6 3.8 6.4 6.3 7.0 5.9 2.3 12.6 2.7 2.4 2.0 43.5 2.0 26.0 2.6 36.9 13.7 18.5 0.6 8.6 3.3 25.9 45.4 4.9 6.3 7.9 0.9 5.2 1.0 6.3 6.4 4.8 0.6 12.7 3.0 44.7 7.6 13.7 3.8 15.7 3.2 11.0 0.8 22.2 3.8 10.1 1.0 5.3 17.9 3.9 6.7 22.1 1.3 2.3 10.8 0.5 0.2 29.9 10.2 9.0 3.2 26.4 13.0 1.8 1.4 4.6 1.0 1.8 1.0 0.3 1.1 1.1 0.7 0.1 0.6 1.4 0.9 0.8 3.7 1.2 1.1 0.6 3.4 3.4 3.7 6.2 4.1 4.5 6.0 3.9 4.7 4.8 4.7 5.7 1.2 0.0 7.2 0.7 23.7 19.1 22.2 42.5 23.3 0.3 3.3 4.1 1.2 4.3 8.0 0.0 2.1 47.5 36.1 55.0 0.0 3.0 0.4 0.6 4.3 1.7 4.2 7.8 5.6 4.7 43.9 6.0 11.2 1.3 14.0 3.4 4.2 0.5 48.3 8.4 0.8 29.9 12.2 33.3 19.0 0.1 5.0 45.6 5.4 2.8 36.0 3.0 53.5 5.0 0.9 2.0 46.8 1.9 20.9 29.6 41.9 0.3 11.4 0.5 0.0 0.9 3.6 3.4 6.0 23.6 15.3 37.5 52.7 5.0 23.6 42.0 SH3BP4 ENSG00000130147 "SH3 domain binding protein 4" Q9P0V3 2 234952017-235055714 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 83.5" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.0;plasmacytoid DC: 3.1" "Lineage enhanced" "Detected in single" "dendritic cells: 3.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037533, HPA037534" Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" "HPA037533: AB_10672903, HPA037534: AB_2675528" "unprognostic (2.16e-3)" "unprognostic (1.43e-1)" "unprognostic (2.83e-2)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (5.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (3.89e-2)" "unprognostic (1.61e-1)" "unprognostic (4.30e-1)" "prognostic favorable (2.07e-6)" "unprognostic (2.86e-2)" "unprognostic (5.08e-2)" "unprognostic (6.91e-2)" "unprognostic (1.17e-2)" 12.4 9.0 17.8 5.7 21.8 1.1 35.3 21.7 15.9 20.8 20.4 13.8 17.2 12.5 14.5 7.7 17.5 19.0 10.2 14.5 16.2 18.3 26.1 13.2 2.2 21.3 21.1 22.5 61.3 5.8 4.0 18.2 20.5 20.3 13.7 2.4 83.5 16.8 9.5 16.6 11.1 13.6 15.8 5.6 25.6 10.2 19.7 4.7 11.1 9.4 3.8 9.4 7.5 28.1 49.3 30.6 77.7 5.8 33.8 22.4 35.2 70.2 66.6 54.6 48.8 23.5 28.8 0.0 19.0 140.4 126.8 26.1 22.6 47.2 64.8 0.2 10.3 0.0 39.5 64.1 55.8 0.0 0.1 43.9 69.9 76.6 41.4 52.4 58.7 0.1 0.4 0.2 81.4 37.8 0.1 0.2 42.5 56.2 16.8 0.0 16.0 9.3 50.0 9.9 47.9 19.3 15.8 101.4 42.7 55.2 11.9 0.2 47.2 59.8 52.2 47.1 45.7 0.0 0.1 0.2 55.6 0.1 89.2 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.1 17.8 21.8 21.7 15.9 14.5 16.2 21.3 21.1 20.5 15.8 19.7 28.1 23.5 3.2 9.1 4.2 1.0 14.8 50.2 15.6 14.2 2.3 37.3 18.0 6.6 18.6 22.5 7.3 6.2 8.7 3.9 6.0 9.8 24.7 3.4 21.4 10.9 22.9 6.6 1.3 0.7 24.8 29.9 11.7 14.8 29.2 1.3 10.0 17.2 26.8 2.1 3.3 1.4 9.1 16.2 1.4 13.1 4.9 8.1 10.9 24.9 20.6 2.6 1.3 0.0 18.1 52.4 39.6 6.3 9.4 0.2 96.9 0.8 1.9 20.7 0.7 0.0 1.9 12.4 0.8 2.8 8.8 11.1 37.1 0.5 5.5 18.0 30.4 SH3D21 "C1orf113, FLJ22938" ENSG00000214193 "SH3 domain containing 21" A4FU49 1 36306368-36329340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.9;thyroid gland: 27.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 15.3;Late spermatids: 53.6;Proximal enterocytes: 14.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 14.4;HaCaT: 21.1;hTERT-RPE1: 21.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042212, HPA042456, HPA066168" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042212: AB_10961180, HPA042456: AB_10959746, HPA066168: AB_2685627" "prognostic favorable (2.60e-4)" "unprognostic (8.35e-3)" "unprognostic (3.86e-3)" "unprognostic (9.01e-2)" "unprognostic (2.07e-3)" "unprognostic (7.32e-3)" "unprognostic (2.04e-4)" "unprognostic (7.47e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.43e-2)" "unprognostic (7.38e-3)" "prognostic unfavorable (1.76e-6)" "unprognostic (8.88e-2)" "unprognostic (2.25e-1)" "unprognostic (7.99e-2)" "unprognostic (8.59e-2)" 1.1 0.7 2.4 2.5 1.1 1.3 10.8 0.2 6.8 4.4 0.0 3.4 14.0 2.2 1.4 6.9 1.2 2.0 2.0 0.8 0.0 8.8 0.8 3.9 2.0 1.1 0.2 3.5 0.5 0.3 1.7 3.1 1.0 6.7 3.7 3.2 13.4 1.4 0.8 17.4 20.9 1.1 0.0 2.2 2.0 6.8 0.8 0.7 27.8 0.3 3.0 1.3 7.2 0.2 11.2 0.3 2.0 2.2 0.5 1.3 14.4 6.1 0.9 2.8 1.3 7.1 4.3 2.2 5.5 1.6 0.3 21.1 1.4 3.3 2.1 0.9 2.1 2.1 4.8 5.3 1.1 1.2 3.2 0.9 3.0 1.9 1.4 21.7 1.0 4.3 0.4 2.6 1.6 7.3 1.4 1.1 1.2 2.6 2.4 2.3 0.3 1.2 3.7 1.8 4.4 2.1 1.1 11.0 3.4 10.3 0.7 0.3 3.2 1.6 1.2 4.3 1.0 3.3 1.0 2.2 3.9 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 2.4 1.1 0.2 6.8 0.8 0.0 1.1 0.2 1.0 0.0 0.8 0.2 1.1 0.0 2.0 0.3 1.7 3.1 1.7 3.0 1.8 6.9 6.2 4.3 1.4 0.0 1.9 5.5 0.0 2.9 1.9 15.3 1.9 0.6 14.2 2.5 2.0 1.6 0.0 0.0 1.6 0.4 2.2 1.9 4.6 7.7 1.3 2.6 1.1 0.3 7.7 11.8 1.2 2.9 2.0 6.1 7.7 53.6 1.2 5.0 3.6 0.0 2.2 1.2 1.0 0.0 0.2 4.3 5.8 2.6 2.9 2.6 14.9 1.1 2.3 1.2 0.0 0.7 2.1 2.6 1.2 2.4 3.1 5.7 1.3 3.2 1.6 1.3 SH3RF2 "FLJ23654, Hepp1, POSHER, PPP1R39, RNF158" ENSG00000156463 "SH3 domain containing ring finger 2" Q8TEC5 5 145936578-146081791 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 58.1;skeletal muscle: 42.4;skin 1: 56.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 7869.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "basal ganglia: 6.1;cerebral cortex: 4.1;thalamus: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 70.3;GAMG: 29.8;hTERT-RPE1: 33.5" "Region enriched" "Detected in many" 14 "basal ganglia: 26.7" "Region enhanced" "Detected in many" "basal ganglia: 9.7" "HPA035903, HPA058119" Uncertain Enhanced Nucleoplasm NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA035903: AB_10696515, HPA058119: AB_2683611" "unprognostic (8.90e-3)" "unprognostic (2.00e-3)" "unprognostic (5.11e-3)" "unprognostic (1.66e-2)" "unprognostic (1.45e-3)" "unprognostic (1.47e-2)" "unprognostic (9.96e-3)" "unprognostic (8.22e-2)" "unprognostic (3.92e-1)" "unprognostic (7.37e-3)" "unprognostic (2.44e-3)" "unprognostic (1.66e-1)" "unprognostic (2.98e-2)" "unprognostic (5.21e-2)" "unprognostic (1.46e-1)" "unprognostic (2.64e-2)" "unprognostic (4.13e-3)" 1.9 0.9 0.6 2.5 6.1 0.0 4.7 0.0 4.1 7.6 0.2 14.3 16.0 1.1 3.6 34.1 6.1 11.9 58.1 0.9 0.5 0.9 7.0 2.7 0.2 0.0 0.3 0.4 15.4 0.0 1.6 0.1 0.0 2.7 14.3 0.5 12.1 0.6 42.4 56.8 13.7 1.1 0.0 0.0 20.5 6.8 1.7 1.0 6.3 8.8 7.7 1.2 20.6 0.4 21.0 5.7 0.2 1.1 0.0 0.0 0.0 0.2 1.7 4.1 1.7 70.3 19.0 0.0 10.5 0.9 29.8 18.9 0.0 22.4 4.0 0.3 0.3 0.0 8.5 9.5 1.2 0.0 0.0 0.2 11.9 6.4 14.8 33.5 0.2 0.5 0.0 0.0 1.8 0.1 0.0 0.0 1.6 17.3 1.5 0.0 0.2 0.0 8.7 2.0 0.0 0.0 1.2 0.4 0.5 1.0 6.6 0.1 9.8 0.8 17.3 1.5 6.7 0.0 0.0 0.0 10.6 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.6 6.1 0.0 4.1 0.9 0.5 0.0 0.3 0.0 0.0 1.7 0.4 4.1 16.0 2.3 1.6 0.0 55.1 5.4 14.5 38.7 0.4 3.9 3.3 510.0 8.6 6.7 1.8 0.0 0.2 0.2 38.9 0.0 5.7 1511.3 11.9 0.9 9.7 1.2 0.0 10.5 8.7 0.0 15.4 50.4 26.7 1.3 0.1 0.7 8.4 0.2 0.0 2.2 16.1 8.2 0.0 4.9 7869.1 25.7 2.6 8.8 10.3 0.6 1.6 0.0 1.5 0.7 21.4 22.9 34.6 0.6 2.2 26.6 0.9 4.4 0.1 13.1 1.6 6.3 31.4 20.7 70.9 50.0 0.0 0.7 2.9 33.2 6.6 SH3TC2 "CMT4C, KIAA1985" ENSG00000169247 "SH3 domain and tetratricopeptide repeats 2" Q8TF17 5 148923639-149063163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.6;retina: 3.9" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 270.4" "Cancer enhanced" "Detected in some" "melanoma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.6;HBEC3-KT: 2.2;RT4: 3.6;SK-MEL-30: 5.2;WM-115: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037683, HPA037684" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA037683: AB_2675608, HPA037684: AB_10672603" "unprognostic (6.30e-2)" "unprognostic (4.07e-2)" "unprognostic (4.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.70e-1)" "unprognostic (1.92e-2)" "unprognostic (2.49e-1)" "unprognostic (2.17e-4)" "unprognostic (2.18e-2)" "unprognostic (4.53e-1)" "unprognostic (6.21e-3)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" "unprognostic (6.48e-2)" "unprognostic (1.84e-1)" "unprognostic (6.62e-2)" "unprognostic (1.40e-1)" 0.1 0.0 4.7 0.0 8.0 0.1 0.1 5.1 5.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.3 3.6 5.1 0.0 0.0 0.0 0.0 7.1 6.9 0.0 0.0 0.0 0.0 0.4 7.3 0.0 0.0 3.9 0.1 0.1 0.2 0.1 0.0 0.0 5.8 0.0 0.0 1.5 7.1 0.0 0.0 0.1 0.0 0.1 0.0 12.6 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.3 0.1 2.6 1.5 0.0 1.8 0.1 0.6 1.9 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 1.1 1.6 0.0 1.3 0.0 0.7 3.6 0.0 0.0 0.0 0.0 5.2 0.1 0.0 0.0 0.2 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.0 5.1 5.0 3.6 5.1 7.1 6.9 7.3 5.8 7.1 12.6 1.9 3.2 3.7 0.3 0.1 0.9 0.8 1.0 0.0 1.4 0.7 0.4 1.7 1.5 3.8 0.0 4.2 0.8 0.0 0.6 0.0 0.6 6.4 0.3 0.1 2.8 0.0 0.0 0.4 0.2 0.4 0.5 0.0 0.5 2.5 0.1 1.4 0.3 0.4 0.0 0.4 0.0 2.0 1.8 0.7 2.3 0.3 2.2 0.0 4.7 0.1 2.3 0.0 0.0 270.4 1.6 0.0 0.0 0.1 1.2 0.0 0.1 4.1 25.4 0.0 0.3 0.4 2.3 0.9 1.0 0.9 11.9 0.3 0.1 0.2 8.8 SHANK2 "CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3" ENSG00000162105 "SH3 and multiple ankyrin repeat domains 2" Q9UPX8 11 70467854-71252577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.5;Horizontal cells: 136.3;Inhibitory neurons: 167.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 7.7;basal ganglia: 7.5;cerebral cortex: 9.3;hippocampal formation: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 11.5;Karpas-707: 17.5;RT4: 15.9;T-47d: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008174, HPA017220" Approved Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Nuclear speckles" "HPA008174: AB_1856822, HPA017220: " "unprognostic (3.08e-1)" "unprognostic (1.31e-3)" "unprognostic (1.79e-1)" "unprognostic (1.51e-2)" "unprognostic (1.51e-1)" "unprognostic (7.23e-5)" "unprognostic (1.24e-1)" "unprognostic (6.67e-2)" "unprognostic (1.83e-2)" "unprognostic (8.42e-2)" "unprognostic (4.87e-2)" "unprognostic (4.01e-1)" "prognostic favorable (1.94e-6)" "unprognostic (3.46e-2)" "unprognostic (2.34e-1)" "unprognostic (4.03e-2)" "unprognostic (4.80e-2)" 1.3 1.2 7.7 0.5 7.5 0.0 4.5 0.2 9.3 1.3 31.7 2.4 1.5 1.0 2.2 3.4 5.1 0.8 0.0 9.5 0.0 4.9 3.8 3.7 0.1 0.0 0.0 0.1 7.5 0.1 2.2 1.9 0.0 3.2 2.0 5.5 9.8 1.8 0.0 0.9 1.3 0.4 0.0 1.1 3.0 0.9 1.0 0.0 6.0 0.0 0.4 1.1 0.3 0.9 0.5 7.4 4.1 0.0 0.6 0.4 4.5 0.7 0.3 0.0 0.0 6.6 3.1 6.2 2.2 0.0 0.1 1.1 0.0 4.8 0.0 0.0 0.2 0.0 0.0 11.5 0.0 0.0 1.9 0.1 1.8 0.0 0.0 1.6 0.0 0.1 0.0 17.5 1.7 10.5 0.0 0.1 3.5 10.2 0.3 0.0 9.9 8.2 5.2 15.9 3.5 1.1 0.0 8.4 0.0 5.2 16.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 7.5 0.2 9.3 9.5 0.0 0.0 0.0 0.0 0.0 1.0 0.9 8.0 41.7 17.0 21.5 0.2 0.0 3.2 3.2 0.6 17.9 26.9 13.0 3.7 11.5 5.4 7.3 0.0 12.8 0.4 3.2 3.9 8.4 1.7 30.0 3.2 1.3 0.0 0.0 153.5 2.2 2.9 1.8 10.2 13.0 2.5 1.2 0.4 21.9 1.2 136.3 167.5 7.9 8.2 0.0 0.3 2.1 0.0 0.4 5.4 14.0 0.0 4.6 0.0 41.7 5.3 10.7 2.7 0.7 0.4 10.9 0.6 10.8 23.3 1.0 0.0 0.3 1.3 0.7 0.9 1.3 0.6 14.6 0.3 0.1 5.5 4.0 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHC4 "RaLP, SHCD" ENSG00000185634 "SHC adaptor protein 4" Q6S5L8 15 48823741-48963919 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.6;testis: 10.5" "Cell type enhanced" "Detected in some" "Astrocytes: 16.6;Oligodendrocyte precursor cells: 30.7;Oligodendrocytes: 81.8" "Cancer enhanced" "Detected in some" "melanoma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AN3-CA: 10.0;SK-MEL-30: 19.1;WM-115: 16.5" "Low region specificity" "Detected in all" HPA074146 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA074146: AB_2686667" "unprognostic (4.34e-3)" "unprognostic (1.01e-3)" "unprognostic (6.70e-2)" "unprognostic (1.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.05e-3)" "unprognostic (1.23e-2)" "unprognostic (3.47e-2)" "unprognostic (2.59e-1)" "unprognostic (2.21e-2)" "unprognostic (3.80e-2)" "unprognostic (3.71e-1)" "unprognostic (1.04e-5)" "unprognostic (9.84e-3)" "unprognostic (3.26e-2)" "unprognostic (3.49e-2)" "unprognostic (1.36e-2)" 0.5 0.9 12.7 1.0 21.0 0.1 1.6 15.8 18.9 1.0 6.7 2.8 0.3 0.4 0.9 0.5 1.0 1.4 3.3 14.0 14.3 0.3 0.1 0.3 0.3 18.3 16.9 0.5 0.2 0.1 1.0 0.4 19.0 0.7 0.5 0.9 2.1 1.3 0.9 0.6 0.8 0.7 13.6 0.2 0.7 10.5 17.8 0.3 0.3 1.2 0.1 0.4 0.9 36.6 0.0 0.4 1.0 10.0 0.4 1.3 0.0 1.5 2.9 0.6 1.2 0.0 0.3 0.1 2.6 0.6 0.1 0.0 0.2 0.4 0.8 2.2 0.1 0.6 0.0 0.0 1.1 0.0 0.2 1.9 0.0 1.3 0.1 1.3 0.1 1.0 0.0 0.2 1.4 1.9 0.4 0.2 0.1 0.0 3.7 0.2 2.7 0.3 2.1 0.4 0.5 0.8 0.2 0.1 19.1 0.9 0.0 0.1 0.0 0.9 0.5 0.6 1.0 0.9 0.1 0.1 0.8 0.5 16.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 21.0 15.8 18.9 14.0 14.3 18.3 16.9 19.0 13.6 17.8 36.6 0.2 0.0 0.0 16.6 0.0 0.3 0.0 2.3 0.0 0.6 1.6 6.7 2.5 0.0 2.8 0.0 0.0 0.7 0.0 0.0 0.0 6.4 2.5 0.4 0.4 0.2 0.0 0.0 9.3 0.0 0.2 1.8 0.0 0.3 0.0 0.0 0.7 0.0 0.1 1.7 6.1 0.0 0.0 0.0 0.4 4.5 1.2 0.1 7.2 1.0 0.0 2.7 0.0 30.7 81.8 0.2 0.0 3.4 0.0 0.0 0.0 0.1 2.6 1.0 0.0 0.5 0.3 6.0 6.3 0.1 0.3 0.8 0.3 0.5 0.0 0.0 SHF ENSG00000138606 "Src homology 2 domain containing F" Q7M4L6 15 45167214-45201175 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 143.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 50.6;Granulosa cells: 58.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 143.8" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 121.0;SH-SY5Y: 54.1" "Region enriched" "Detected in all" 5 "cerebellum: 240.6" "Region enriched" "Detected in all" 4 "cerebellum: 106.2" HPA057381 Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA057381: AB_2683423" "unprognostic (4.05e-2)" "unprognostic (2.02e-3)" "unprognostic (7.59e-2)" "unprognostic (1.54e-1)" "unprognostic (1.88e-2)" "unprognostic (2.18e-1)" "unprognostic (2.38e-1)" "unprognostic (7.61e-2)" "unprognostic (2.18e-1)" "unprognostic (3.50e-2)" "unprognostic (6.88e-2)" "unprognostic (5.12e-2)" "unprognostic (6.89e-2)" "unprognostic (2.83e-2)" "unprognostic (1.17e-1)" "unprognostic (5.09e-3)" "unprognostic (1.83e-2)" 6.1 22.7 21.9 4.3 20.5 1.0 6.3 143.8 27.8 14.4 0.2 13.4 13.1 11.9 4.7 5.0 10.5 6.6 9.0 21.5 19.5 4.4 38.6 5.6 2.7 12.8 16.9 23.7 3.1 4.4 8.3 1.9 15.9 10.1 5.3 7.1 6.7 5.9 3.8 12.7 8.4 7.5 9.4 4.3 6.7 8.4 21.4 2.4 7.5 4.7 1.9 10.2 11.7 13.4 0.1 1.4 24.0 0.7 1.8 0.9 11.2 3.0 2.1 6.7 9.5 3.6 11.6 1.3 9.5 4.2 6.6 2.1 9.2 0.7 3.2 2.2 4.2 0.8 2.2 24.8 1.0 0.1 8.0 2.2 0.6 0.9 0.2 5.0 5.2 12.0 5.0 0.5 9.5 4.1 5.5 0.9 9.6 4.5 0.6 15.0 19.1 0.5 2.3 0.5 121.0 54.1 0.7 0.8 0.4 7.4 1.2 2.4 0.3 0.8 10.0 0.7 0.4 1.1 0.9 1.1 0.3 0.6 3.8 0.1 0.6 0.5 1.3 0.6 1.4 0.8 0.5 0.8 0.6 1.5 0.7 0.5 0.8 2.0 0.6 0.9 0.1 0.5 21.9 20.5 143.8 27.8 21.5 19.5 12.8 16.9 15.9 9.4 21.4 13.4 4.1 0.0 0.6 3.3 4.2 3.6 5.8 1.7 0.0 50.6 3.6 5.5 2.8 0.0 1.3 0.0 0.0 1.1 2.6 2.1 0.0 0.8 7.9 1.1 3.5 5.7 13.1 0.0 5.9 1.3 0.5 5.8 1.5 2.2 2.5 58.8 5.3 11.7 0.6 10.1 6.9 10.9 2.0 1.0 15.0 15.3 4.4 2.9 8.8 5.6 0.1 5.9 2.1 9.0 1.8 0.7 5.6 4.1 0.7 3.5 18.0 1.1 0.8 5.0 6.6 6.7 9.6 5.4 2.9 1.4 2.6 0.7 2.8 1.8 4.6 9.7 SHH "HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS" ENSG00000164690 "Sonic hedgehog signaling molecule" Q15465 7 155799980-155812463 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Hydrolase, Protease" "Disease variant, Holoprosencephaly, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 13.6;stomach 1: 10.5;urinary bladder: 16.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 8.3;Cholangiocytes: 18.6;Collecting duct cells: 9.2;Gastric mucus-secreting cells: 9.7;Hepatocytes: 20.1;Intestinal goblet cells: 8.6;Pancreatic endocrine cells: 11.7;Urothelial cells: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.9;GAMG: 39.8;OE19: 10.2;RT4: 25.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 5500000 "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (7.17e-2)" "unprognostic (7.68e-3)" "unprognostic (6.70e-2)" "prognostic favorable (8.62e-5)" "unprognostic (1.59e-1)" "unprognostic (2.50e-2)" "unprognostic (2.39e-3)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.16e-2)" "unprognostic (3.47e-1)" "unprognostic (1.56e-1)" "unprognostic (1.77e-3)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (3.43e-2)" "unprognostic (2.66e-2)" 0.0 8.7 1.3 0.3 1.2 0.0 0.0 1.6 1.2 4.4 0.3 1.3 1.4 0.4 3.0 0.0 0.1 3.8 0.0 0.8 6.2 3.3 13.6 1.7 0.0 3.3 1.6 0.0 0.2 0.0 0.1 0.0 4.6 1.2 1.0 0.3 0.0 1.2 0.0 0.1 1.4 0.0 1.0 0.0 10.5 0.1 2.6 0.0 0.0 0.0 0.0 16.2 0.3 1.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.2 0.0 8.9 0.0 39.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 10.2 4.0 0.0 0.0 0.0 2.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.3 1.2 1.6 1.2 0.8 6.2 3.3 1.6 4.6 1.0 2.6 1.6 0.0 3.2 7.8 0.0 0.0 0.0 8.3 0.0 0.0 1.5 0.0 0.0 0.7 18.6 1.3 9.2 0.0 0.0 0.0 3.7 0.0 1.2 4.7 5.4 0.5 0.2 0.0 0.0 0.1 0.8 0.2 0.1 9.7 7.6 0.0 0.0 0.4 20.1 0.0 0.0 0.4 8.6 0.0 0.6 0.0 1.7 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.7 0.5 0.4 0.1 1.3 2.5 6.6 0.0 0.1 0.0 0.0 0.1 2.7 0.2 0.0 0.0 0.0 0.0 0.0 3.0 8.3 SHISA2 "bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166" ENSG00000180730 "Shisa family member 2" Q6UWI4 13 26044597-26052016 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 12.4;skeletal muscle: 14.2;thyroid gland: 21.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 13.1;Basal prostatic cells: 14.6;Breast glandular cells: 24.1;Oligodendrocytes: 10.9;Urothelial cells: 19.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 25.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 26.7;JURKAT: 20.8;LHCN-M2: 18.7;NTERA-2: 15.5;RH-30: 46.3;U-2197: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049752, HPA050172" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nuclear bodies, Vesicles" "HPA049752: , HPA050172: AB_2681041" "unprognostic (2.08e-2)" "unprognostic (3.00e-1)" "unprognostic (2.41e-1)" "unprognostic (9.71e-2)" "unprognostic (6.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.30e-4)" "unprognostic (4.03e-2)" "unprognostic (3.10e-1)" "unprognostic (7.45e-2)" "unprognostic (2.17e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.56e-3)" "unprognostic (2.09e-1)" "unprognostic (3.46e-1)" "unprognostic (1.51e-2)" 0.5 0.0 1.1 0.2 2.3 0.1 12.4 1.5 2.0 1.7 0.9 0.1 0.7 0.1 7.8 0.2 0.2 0.5 0.2 2.0 1.5 4.7 0.0 4.3 0.5 1.9 1.5 0.3 0.3 0.1 1.6 0.0 1.6 0.5 0.1 0.0 2.7 0.3 14.2 1.1 0.7 0.1 2.2 0.2 2.1 1.2 1.6 2.5 21.0 1.2 0.7 0.7 0.0 5.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.8 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.4 4.2 1.4 0.0 0.0 1.7 26.7 1.0 20.8 0.0 0.0 18.7 1.2 2.3 0.5 15.5 8.4 8.2 0.0 46.3 0.3 1.7 6.5 0.4 0.0 0.4 0.0 5.4 2.6 0.7 0.2 1.6 0.1 0.7 30.4 7.0 0.0 0.0 0.0 0.0 0.0 4.1 0.8 0.1 0.5 0.1 0.2 0.2 0.1 0.4 0.1 0.0 0.2 1.0 1.6 0.4 0.2 0.3 0.1 0.2 0.1 1.1 2.3 1.5 2.0 2.0 1.5 1.9 1.5 1.6 2.2 1.6 5.4 4.7 0.0 13.1 0.0 0.4 5.4 14.6 2.3 0.6 0.0 24.1 6.2 0.5 0.0 1.5 3.7 0.0 0.3 0.3 0.1 0.0 6.0 2.6 1.0 0.5 5.1 0.0 0.0 0.0 0.2 0.3 2.8 3.1 2.5 0.0 2.4 1.1 0.0 0.8 0.0 1.0 0.1 8.2 0.3 2.3 1.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.5 10.9 1.2 0.0 0.4 0.2 3.9 0.0 0.3 1.1 0.0 0.0 7.6 1.6 0.7 5.1 0.4 1.7 0.1 1.1 0.7 0.0 19.6 SHOX2 "OG12, OG12X, SHOT" ENSG00000168779 "Short stature homeobox 2" O60902 3 158095905-158106420 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 7.8;brain: 26.4" "Cell type enriched" "Detected in some" 6 "Early spermatids: 90.3" "Cancer enhanced" "Detected in many" "glioma: 3.4" "Region enhanced" "Detected in many" "thalamus: 26.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.2;THP-1: 38.7" "Group enriched" "Detected in many" 5 "midbrain: 36.0;thalamus: 54.8" "Group enriched" "Detected in some" 6 "midbrain: 10.6;pons: 16.3;thalamus: 32.1" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.62e-1)" "unprognostic (6.32e-2)" "unprognostic (3.32e-2)" "unprognostic (1.08e-3)" "unprognostic (1.51e-1)" "unprognostic (1.69e-3)" "unprognostic (2.28e-3)" "unprognostic (7.66e-2)" "unprognostic (7.35e-2)" "unprognostic (2.23e-1)" "unprognostic (6.31e-2)" "unprognostic (8.75e-3)" "unprognostic (0.00e+0)" "unprognostic (4.20e-3)" "unprognostic (2.12e-1)" "unprognostic (3.95e-2)" "unprognostic (2.76e-3)" 7.8 0.1 8.9 0.0 0.5 0.1 5.4 0.0 1.1 3.9 0.0 0.1 0.0 0.4 0.1 0.0 0.2 0.2 3.4 0.1 6.1 0.0 0.0 0.2 1.7 10.6 13.0 0.2 0.1 0.3 0.2 0.2 7.0 0.1 0.0 0.0 2.2 0.4 1.3 2.2 0.1 0.0 0.5 0.0 0.2 3.4 26.4 0.0 0.5 0.4 0.3 0.4 1.0 0.2 5.5 0.6 0.3 8.1 24.2 15.3 1.5 8.9 3.4 4.8 8.2 1.8 0.7 1.2 0.2 12.8 9.5 0.1 10.1 0.0 1.9 5.1 2.9 13.7 2.7 0.0 0.0 1.2 10.7 6.9 0.3 4.4 0.5 14.8 0.0 0.7 3.8 0.9 2.1 0.3 0.0 0.7 0.0 0.1 0.5 6.2 7.4 1.4 0.0 0.0 2.7 20.5 1.0 0.2 5.2 0.1 0.2 38.7 0.5 15.0 3.1 16.6 14.8 1.1 2.9 0.9 14.5 7.3 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 8.9 0.5 0.0 1.1 0.1 6.1 10.6 13.0 7.0 0.5 26.4 0.2 3.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.2 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 90.3 0.1 1.7 0.9 0.0 0.0 0.0 0.2 0.7 9.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 1.9 1.2 13.9 2.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 13.1 1.1 8.5 5.7 2.8 0.0 0.4 0.3 0.1 0.0 0.2 0.0 SHROOM1 "APXL2, KIAA1960" ENSG00000164403 "Shroom family member 1" Q2M3G4 5 132822141-132830659 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 116.9;prostate: 73.9;urinary bladder: 62.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.0;Hepatocytes: 79.2;Proximal enterocytes: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 24.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037690, HPA037691" Uncertain Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA037690: AB_2675613, HPA037691: AB_2675614" "unprognostic (2.50e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (2.66e-1)" "unprognostic (1.45e-2)" "unprognostic (3.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.33e-2)" "unprognostic (3.74e-1)" "unprognostic (3.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.22e-2)" "unprognostic (2.91e-2)" "unprognostic (2.88e-2)" "unprognostic (2.26e-3)" 9.3 2.4 25.2 2.6 32.0 0.2 8.2 28.9 26.9 12.6 10.4 20.5 6.1 11.3 2.1 5.1 8.4 6.7 7.6 20.2 23.6 10.7 116.9 10.5 0.6 42.1 30.9 5.6 16.2 4.9 6.8 11.8 33.3 73.9 11.1 3.4 7.0 15.2 1.7 1.5 16.6 3.9 26.1 2.3 10.9 1.7 31.2 0.6 6.9 1.3 0.5 62.4 9.3 55.7 8.6 5.1 0.9 0.8 1.4 4.0 9.0 9.1 7.7 7.0 7.8 11.2 5.7 1.5 12.5 4.9 3.8 0.8 3.1 5.7 4.3 9.5 11.0 0.3 8.7 10.5 4.1 0.7 3.1 1.7 3.0 4.9 3.0 4.8 4.8 0.1 7.3 8.1 6.1 4.8 0.2 4.0 1.4 6.7 8.1 0.5 0.0 0.8 1.2 24.4 5.7 1.5 8.8 0.7 4.9 4.5 5.2 2.9 4.5 8.1 11.7 1.1 11.5 9.2 6.8 0.1 7.9 0.0 2.5 0.2 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 25.2 32.0 28.9 26.9 20.2 23.6 42.1 30.9 33.3 26.1 31.2 55.7 18.3 25.6 22.3 18.9 1.8 1.3 15.4 2.3 3.4 3.7 9.3 5.5 2.2 30.0 11.3 9.2 10.4 6.8 1.0 135.0 1.9 6.0 0.9 7.1 17.3 18.1 22.8 2.7 3.0 10.7 4.8 6.1 33.6 15.1 8.2 9.0 25.0 79.2 6.6 16.8 1.0 28.6 0.0 8.7 5.5 1.1 4.7 4.6 0.0 23.4 8.1 19.9 3.1 6.6 37.5 7.1 53.6 4.9 3.6 31.6 65.5 3.5 9.1 13.3 26.3 2.8 5.1 7.6 5.1 1.8 2.0 2.9 2.5 1.4 35.5 17.3 SHROOM3 "APXL3, KIAA1481, SHRM, ShrmL" ENSG00000138771 "Shroom family member 3" Q8TF72 4 76435229-76783253 "Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 313.1;Distal enterocytes: 154.5;Endometrial ciliated cells: 182.9;Glandular and luminal cells: 350.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 40.8;AF22: 38.2;BJ hTERT+: 36.9;EFO-21: 39.9;OE19: 40.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047784 Enhanced NA NA "Cluster 37: Intestine - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA047784: AB_2680155" "unprognostic (1.96e-1)" "unprognostic (2.50e-1)" "unprognostic (1.57e-2)" "unprognostic (5.33e-2)" "unprognostic (1.61e-2)" "unprognostic (3.33e-2)" "unprognostic (7.96e-3)" "unprognostic (2.70e-2)" "unprognostic (1.92e-1)" "unprognostic (2.90e-1)" "unprognostic (1.45e-3)" "unprognostic (1.03e-1)" "prognostic favorable (1.64e-13)" "unprognostic (2.87e-2)" "unprognostic (2.25e-1)" "unprognostic (9.06e-2)" "unprognostic (1.87e-2)" 1.0 2.0 0.4 6.1 1.8 0.1 15.4 12.4 3.4 5.9 18.5 20.0 15.2 3.0 13.9 17.5 15.7 17.8 3.9 0.9 0.0 7.0 6.2 8.5 0.4 6.1 2.1 0.5 6.5 12.9 3.3 4.4 5.9 9.0 17.2 9.7 25.7 6.3 0.1 3.0 14.7 9.7 5.6 6.1 21.9 0.7 0.2 0.9 3.5 0.1 2.4 4.9 2.3 3.0 40.8 7.9 38.2 25.2 0.0 0.6 1.4 12.4 36.9 0.8 1.6 6.8 26.3 0.6 39.9 34.6 3.0 20.4 5.1 17.8 0.7 0.1 6.7 0.0 7.5 0.0 0.2 0.0 0.0 0.3 4.3 1.3 6.7 9.7 0.7 0.3 0.0 9.7 0.8 3.6 0.7 0.1 16.0 40.5 4.7 3.5 6.3 6.3 6.0 0.9 15.0 19.9 5.2 28.2 2.1 23.2 6.8 0.2 0.0 6.5 5.5 0.2 5.4 12.0 13.3 0.1 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.8 12.4 3.4 0.9 0.0 6.1 2.1 5.9 5.6 0.2 3.0 0.6 89.8 53.4 313.1 1.0 0.9 5.8 14.0 2.8 35.8 69.9 46.1 11.0 81.5 40.0 35.0 75.0 0.4 0.6 154.5 0.0 33.6 7.1 182.9 27.1 2.1 86.9 2.7 54.5 36.4 0.7 4.7 103.0 350.1 0.0 11.9 0.7 42.2 0.2 1.7 19.1 104.0 30.5 1.6 0.3 3.2 0.3 1.8 3.6 29.0 1.6 7.2 0.0 6.0 2.1 73.8 92.3 0.0 0.3 35.8 102.7 6.8 65.7 31.1 0.0 0.3 7.4 3.4 2.4 3.5 0.3 0.1 1.7 0.3 70.5 11.9 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SIGLEC6 "CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6" ENSG00000105492 "Sialic acid binding Ig like lectin 6" O43699 19 51517819-51531856 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "placenta: 106.7" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 76.0;granulocytes: 55.0;Syncytiotrophoblasts: 188.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.9;memory B-cell: 7.2;naive B-cell: 4.5;plasmacytoid DC: 11.0" "Group enriched" "Detected in many" 13 "B-cells: 7.2;dendritic cells: 11.0;granulocytes: 4.9" "Cell line enriched" "Detected in some" 7 "HMC-1: 500.7" "HPA008945, HPA009084, HPA018198" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA008945: , HPA009084: AB_1079967, HPA018198: AB_1856868" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (9.31e-3)" "unprognostic (8.46e-4)" "unprognostic (2.91e-1)" "unprognostic (2.02e-2)" "unprognostic (2.64e-1)" "unprognostic (8.96e-2)" "unprognostic (2.03e-1)" "unprognostic (6.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.15e-2)" "unprognostic (4.42e-2)" "unprognostic (3.28e-2)" "unprognostic (5.57e-3)" 0.6 0.1 0.2 3.0 0.3 0.5 0.7 0.4 0.3 1.6 0.1 2.2 2.2 1.5 1.0 2.5 0.3 2.5 0.4 0.2 0.0 0.1 0.1 4.3 3.8 0.1 0.1 0.1 0.3 0.1 0.0 106.7 0.2 1.0 3.1 0.4 0.5 0.7 0.5 0.5 3.3 1.3 0.0 1.7 2.6 0.3 0.2 0.7 0.0 0.6 4.2 1.8 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 15.8 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 1.2 500.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 19.1 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.9 0.2 4.9 0.1 0.0 0.0 0.0 0.0 7.2 0.0 0.0 1.6 4.5 0.0 0.0 0.2 0.6 0.0 11.0 0.0 0.4 0.2 0.3 0.4 0.3 0.2 0.0 0.1 0.1 0.2 0.0 0.2 0.5 0.0 0.0 1.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 5.2 0.7 0.0 0.0 55.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.7 0.5 0.0 0.0 0.0 SIGLEC8 "MGC59785, SAF2, SIGLEC-8, SIGLEC8L" ENSG00000105366 "Sialic acid binding Ig like lectin 8" Q9NYZ4 19 51450847-51458456 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.9;lymphoid tissue: 6.8" "Cell type enhanced" "Detected in some" "granulocytes: 44.9;Kupffer cells: 17.7;Microglial cells: 11.2" "Group enriched" "Detected in many" 4 "glioma: 7.2;renal cancer: 2.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 38 "eosinophil: 290.2" "Lineage enriched" "Detected in single" 719 "granulocytes: 290.2" "Cell line enriched" "Detected in some" 44 "HMC-1: 147.5" HPA012556 Uncertain Uncertain Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Cytosol "HPA012556: AB_1856869" "unprognostic (1.27e-1)" "unprognostic (1.88e-4)" "unprognostic (1.28e-1)" "unprognostic (6.70e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-2)" "unprognostic (7.84e-2)" "unprognostic (2.51e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-1)" "unprognostic (1.10e-1)" "unprognostic (4.19e-1)" "unprognostic (8.62e-3)" "unprognostic (7.18e-2)" "unprognostic (6.02e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" 0.3 4.0 4.9 1.6 5.2 0.5 1.4 5.3 6.1 0.9 1.7 1.8 1.8 0.6 0.7 0.7 0.7 1.4 0.2 4.5 6.2 0.1 0.8 2.5 6.8 13.3 6.6 0.2 0.5 1.0 0.4 0.1 10.1 0.6 1.6 0.7 0.6 0.5 0.1 0.5 2.8 0.9 7.3 6.3 1.4 0.3 11.6 2.1 0.4 0.2 2.5 1.0 0.3 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 2.3 0.1 0.1 0.0 0.0 147.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.3 0.0 0.0 0.2 3.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.2 1.1 0.1 7.6 0.4 290.2 0.2 0.3 0.1 0.2 0.2 0.1 0.1 0.3 0.1 0.2 2.5 0.3 0.4 0.2 0.1 0.2 4.9 5.2 5.3 6.1 4.5 6.2 13.3 6.6 10.1 7.3 11.6 14.9 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 44.9 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 2.5 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SIGMAR1 "OPRS1, SR-BP1" ENSG00000147955 "Sigma non-opioid intracellular receptor 1" Q99720 9 34634722-34637844 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Receptor "Amyotrophic lateral sclerosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 187.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 98.7;Hepatocytes: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013470, HPA018002, HPA024071" Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 33: Fibroblasts - ECM organization" "CAB013470: AB_2533521, HPA018002: AB_1854802, HPA024071: AB_1854803" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (1.56e-1)" "unprognostic (1.95e-1)" "unprognostic (8.06e-2)" "unprognostic (3.71e-2)" "unprognostic (4.89e-2)" "unprognostic (2.50e-2)" "unprognostic (2.58e-2)" "unprognostic (2.01e-3)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (2.78e-2)" "unprognostic (2.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.42e-4)" 42.0 52.4 25.2 19.4 25.3 20.5 38.1 26.2 27.1 53.0 27.4 42.0 46.0 50.7 45.0 54.1 46.9 22.1 34.0 25.8 30.2 25.5 187.6 27.5 16.9 28.3 28.7 46.1 45.7 39.0 22.0 27.6 29.4 35.5 31.2 7.2 35.0 38.5 17.6 53.9 40.0 34.8 26.2 24.2 42.1 20.2 33.3 19.1 29.7 13.5 22.2 46.3 43.5 27.1 184.3 162.6 59.8 175.3 205.7 138.7 66.5 127.1 91.2 115.8 105.9 97.6 76.8 87.8 71.9 151.7 69.8 108.8 94.5 151.3 57.8 144.7 175.6 78.0 225.0 112.7 131.7 145.0 67.6 142.9 163.0 131.2 197.7 59.4 90.2 114.5 30.1 156.2 139.7 1.8 88.2 215.2 68.8 101.5 184.4 101.4 59.6 258.3 111.0 36.5 57.6 65.5 123.3 89.5 70.0 32.0 106.9 98.7 68.5 90.0 69.9 96.4 19.2 43.2 71.6 2.5 97.2 123.9 191.8 24.3 39.5 24.2 43.0 39.3 46.2 26.5 62.5 51.3 48.9 21.1 51.7 43.6 10.7 28.7 42.5 35.1 65.5 43.5 25.2 25.3 26.2 27.1 25.8 30.2 28.3 28.7 29.4 26.2 33.3 27.1 11.0 3.2 13.6 6.8 12.3 18.4 16.8 24.6 14.2 10.1 26.8 18.9 9.2 15.7 12.1 7.3 0.0 44.8 10.7 33.0 0.0 33.0 0.9 7.0 23.7 14.4 10.3 23.5 5.6 33.5 98.7 29.2 18.3 10.1 7.0 19.4 13.9 97.5 38.8 5.0 6.4 28.2 12.2 10.5 7.8 1.8 27.4 10.8 19.6 5.6 9.5 13.8 14.4 5.0 4.4 32.1 31.5 25.6 22.4 25.9 58.4 13.7 6.8 7.7 19.7 12.1 23.9 6.0 10.3 40.0 21.5 36.5 13.6 26.2 47.3 16.1 SIMC1 "C5orf25, FLJ44216, OOMA1, PLEIAD" ENSG00000170085 "SUMO interacting motifs containing 1" Q8NDZ2 5 176238367-176345991 "Predicted intracellular proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 47.0" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.2;Inhibitory neurons: 57.4;Spermatocytes: 83.1;Theca cells: 102.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037889, HPA037890" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA037889: AB_2675720, HPA037890: AB_2675721" "unprognostic (1.15e-1)" "unprognostic (9.97e-2)" "unprognostic (3.81e-3)" "prognostic unfavorable (2.32e-6)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.20e-2)" "unprognostic (5.59e-2)" "unprognostic (2.75e-1)" "unprognostic (1.97e-3)" "unprognostic (1.60e-1)" "unprognostic (1.21e-2)" "unprognostic (1.74e-1)" "unprognostic (2.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.53e-1)" "unprognostic (3.59e-2)" "unprognostic (9.20e-2)" 5.3 28.0 6.8 4.0 6.2 3.8 4.3 7.0 6.8 12.0 7.5 7.1 5.8 12.2 9.9 4.3 13.4 4.0 4.1 6.0 7.3 3.9 8.7 5.0 5.3 4.7 5.0 47.0 6.5 6.0 14.1 5.1 5.3 9.6 6.9 4.6 3.7 6.5 12.1 5.4 7.5 8.5 3.9 10.2 10.2 33.5 8.2 6.8 4.0 4.4 5.5 8.4 6.4 5.9 2.8 6.9 21.6 17.2 11.1 11.3 11.2 9.6 8.7 9.8 11.2 25.7 7.3 0.1 11.5 10.7 20.0 2.5 24.2 18.1 11.9 4.8 17.9 12.7 4.7 3.3 24.5 13.7 9.3 7.4 7.1 6.4 12.1 6.9 9.3 4.6 32.6 11.5 11.5 12.5 13.2 12.3 8.2 3.3 7.5 19.2 15.2 16.6 6.8 5.1 14.3 15.0 11.0 1.7 10.6 8.3 6.1 26.4 6.6 11.6 6.2 10.6 8.4 3.1 3.5 18.9 4.3 9.2 6.9 7.2 3.7 7.0 3.3 3.5 4.0 4.4 4.0 2.6 5.2 4.1 3.3 2.7 0.4 7.3 2.8 2.6 2.9 2.7 6.8 6.2 7.0 6.8 6.0 7.3 4.7 5.0 5.3 3.9 8.2 5.9 4.9 9.6 5.6 24.2 12.6 2.9 5.9 3.2 8.6 18.1 2.1 3.0 4.0 2.8 3.4 1.8 4.2 0.4 15.0 8.9 1.9 3.8 46.5 2.9 15.6 3.6 13.2 2.5 49.1 3.6 2.9 9.2 19.9 4.9 0.0 58.2 5.3 7.2 2.2 18.5 57.4 9.9 0.0 5.7 2.0 14.4 29.8 4.2 5.4 30.9 5.7 6.1 11.3 30.7 7.7 4.7 7.8 34.6 5.7 7.1 12.0 1.9 3.0 5.3 32.9 5.6 6.3 83.1 33.8 5.9 2.6 0.8 7.7 102.8 8.9 3.1 SIPA1L3 "KIAA0545, SPAR3" ENSG00000105738 "Signal induced proliferation associated 1 like 3" O60292 19 37907208-38208369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 93.7;Inhibitory neurons: 87.3;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 59.6" "Low region specificity" "Detected in all" "HPA042072, HPA045480, HPA074988" Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA042072: AB_2677832, HPA045480: AB_2679342, HPA074988: " "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.86e-1)" "unprognostic (5.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-2)" "unprognostic (1.31e-2)" "unprognostic (5.48e-2)" "unprognostic (3.11e-1)" "unprognostic (6.05e-2)" "unprognostic (3.15e-1)" "unprognostic (5.43e-2)" "unprognostic (9.26e-3)" "unprognostic (6.45e-2)" "unprognostic (4.94e-2)" "unprognostic (5.36e-2)" "unprognostic (1.96e-2)" 2.2 3.0 6.0 6.6 3.0 2.9 5.1 10.4 16.2 4.8 2.6 10.6 18.4 3.3 1.3 4.9 4.8 3.9 6.2 28.9 2.0 6.4 3.4 5.7 6.8 4.2 4.1 2.9 9.7 3.3 3.2 1.4 3.5 5.3 7.0 5.0 8.4 3.5 6.5 11.1 18.1 1.8 1.6 7.3 9.1 4.3 5.6 3.8 10.0 7.3 5.5 4.3 3.6 5.5 34.4 59.6 7.3 9.3 4.3 4.3 4.9 14.5 12.2 9.4 8.8 20.6 19.5 19.5 12.2 12.4 7.9 7.6 6.7 27.1 10.4 6.7 3.3 5.3 5.5 6.5 8.3 3.7 5.5 3.3 14.1 17.5 37.3 13.9 10.8 5.6 3.9 4.1 16.6 10.6 5.0 5.1 6.0 27.2 15.8 10.8 5.9 2.9 20.7 29.1 17.3 9.3 16.0 27.1 2.2 3.9 18.0 3.5 23.2 15.6 5.5 48.4 22.6 5.4 10.0 6.6 20.1 4.9 20.6 0.1 0.1 0.4 0.1 0.2 0.0 1.1 0.1 0.2 0.1 1.5 0.1 0.5 0.1 0.3 1.5 0.3 0.1 0.1 6.0 3.0 10.4 16.2 28.9 2.0 4.2 4.1 3.5 1.6 5.6 5.5 4.8 6.4 10.1 41.4 24.5 12.0 5.2 10.4 6.2 21.9 22.6 12.1 5.2 22.8 10.8 23.9 14.6 2.1 9.3 93.7 3.9 7.2 4.5 19.8 4.8 5.4 25.2 10.8 61.1 15.3 1.4 3.7 40.2 16.5 2.5 4.8 6.4 23.5 3.5 33.7 87.3 46.3 20.3 5.1 13.9 9.2 2.1 8.3 5.4 50.6 7.1 3.0 5.2 99.5 58.7 13.4 38.7 1.9 12.8 6.6 50.0 21.1 19.1 5.7 6.6 4.5 3.6 1.7 5.1 8.9 16.1 0.8 5.1 1.7 30.4 5.6 SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 5.1;Kupffer cells: 20.0;Macrophages: 9.5;Microglial cells: 14.0;monocytes: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cell line enhanced" "Detected in some" "A-431: 4.7;HBEC3-KT: 4.0;HMC-1: 7.8;hTCEpi: 8.5;HUVEC TERT2: 4.3;THP-1: 7.7;TIME: 3.7;U-937: 8.3" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" 5.6 2.4 1.1 12.0 1.2 6.5 1.6 1.3 1.6 1.8 1.8 1.5 0.9 0.9 0.1 1.8 1.6 3.7 1.4 1.1 1.5 1.1 1.8 7.2 7.0 2.7 2.1 0.5 0.7 0.6 0.6 7.5 2.4 0.9 1.7 0.2 1.3 0.6 0.5 0.9 2.0 4.1 1.6 13.1 1.2 0.5 2.7 1.4 0.7 1.8 3.2 3.9 0.9 2.6 4.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.8 0.0 8.5 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 3.7 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 8.3 0.0 3.0 51.1 31.7 0.1 30.4 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 69.5 0.0 24.4 0.6 0.0 18.9 1.1 1.2 1.3 1.6 1.1 1.5 2.7 2.1 2.4 1.6 2.7 2.6 0.0 0.0 1.1 0.0 0.5 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.1 1.3 0.0 1.4 0.2 5.1 0.0 0.1 0.0 0.0 20.0 3.3 0.0 0.0 9.5 0.0 14.0 8.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.1 0.7 0.3 0.1 0.0 0.6 SIRT2 SIR2L ENSG00000068903 "Sirtuin 2" Q8IXJ6 19 38878555-38899862 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Meiosis, Mitosis, Neurogenesis, Transcription, Transcription regulation" Transferase "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 302.1;tongue: 218.2" "Cell type enhanced" "Detected in all" "Early spermatids: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004573, HPA011165" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli, Cytosol" Nucleoplasm "CAB004573: AB_2188600, HPA011165: AB_1856900" "unprognostic (2.15e-2)" "unprognostic (2.24e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (7.20e-7)" "unprognostic (3.75e-3)" "unprognostic (1.28e-2)" "unprognostic (2.85e-2)" "unprognostic (2.44e-3)" "unprognostic (2.73e-1)" "unprognostic (4.83e-2)" "unprognostic (2.97e-3)" "unprognostic (1.02e-1)" "unprognostic (1.90e-1)" "unprognostic (3.60e-2)" "unprognostic (1.19e-1)" "unprognostic (8.73e-2)" "unprognostic (1.70e-1)" 43.2 44.0 101.6 11.5 137.5 17.4 39.7 141.1 123.0 41.5 79.4 49.2 12.6 37.2 10.4 42.5 37.2 15.0 76.9 100.7 111.2 35.9 51.5 38.2 13.7 151.0 129.6 49.0 33.4 18.2 31.2 10.5 144.7 32.7 10.2 11.9 41.5 14.9 302.1 48.8 32.4 18.3 121.3 40.1 41.4 43.5 127.6 13.1 34.5 218.2 13.0 41.3 37.8 173.5 16.1 9.8 8.4 20.6 46.7 31.8 5.8 11.3 20.2 17.8 22.7 17.1 10.2 5.4 23.7 21.3 13.2 8.3 14.6 25.1 10.9 25.2 15.6 10.1 10.9 10.9 33.0 7.0 22.4 33.5 29.7 14.4 16.9 21.4 31.9 17.7 10.1 42.0 28.2 8.9 15.4 6.2 1.2 27.6 13.6 19.9 22.8 15.3 14.8 14.9 20.7 9.0 12.9 17.8 13.0 7.0 8.0 19.2 28.9 24.0 5.1 37.2 17.0 16.9 8.8 12.6 18.1 19.0 22.0 48.9 54.7 59.8 44.9 69.1 28.5 24.9 21.9 31.0 42.9 28.9 14.3 23.6 42.7 36.5 56.7 44.0 33.1 51.9 101.6 137.5 141.1 123.0 100.7 111.2 151.0 129.6 144.7 121.3 127.6 173.5 39.5 16.0 19.4 26.1 21.0 51.6 30.3 35.1 35.3 29.7 28.8 29.7 42.1 14.3 27.2 12.9 35.5 36.5 90.8 28.4 37.2 29.0 173.0 24.7 15.4 31.1 17.5 27.1 31.2 17.6 15.2 30.3 44.9 26.5 25.4 29.5 28.5 19.7 66.3 30.3 27.2 24.1 97.6 38.3 51.7 74.8 31.1 37.1 46.2 11.2 20.0 22.6 85.5 76.4 110.8 26.5 23.9 41.0 39.7 14.9 54.0 38.8 30.1 28.2 19.7 113.5 27.9 15.3 7.2 30.1 60.1 42.3 45.8 31.3 18.2 21.5 SIT1 SIT ENSG00000137078 "Signaling threshold regulating transmembrane adaptor 1" Q9Y3P8 9 35649295-35650950 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 95.4" "Cell type enhanced" "Detected in some" "B-cells: 78.9;dendritic cells: 31.2;Plasma cells: 19.8;T-cells: 86.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 46 "gdT-cell: 119.1;MAIT T-cell: 202.7;memory B-cell: 213.6;memory CD4 T-cell: 249.2;memory CD8 T-cell: 223.4;naive B-cell: 192.1;naive CD4 T-cell: 170.4;naive CD8 T-cell: 169.5;plasmacytoid DC: 203.1;T-reg: 352.4" "Group enriched" "Detected in many" 56 "B-cells: 213.6;dendritic cells: 203.1;T-cells: 352.4" "Group enriched" "Detected in some" 5 "Daudi: 113.1;HDLM-2: 70.6;JURKAT: 58.7;U-698: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA018506 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA018506: AB_2669896" "unprognostic (4.28e-3)" "prognostic favorable (6.56e-4)" "unprognostic (8.01e-3)" "prognostic favorable (1.94e-6)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-4)" "unprognostic (1.75e-2)" "unprognostic (9.34e-3)" "prognostic favorable (8.17e-4)" "unprognostic (2.00e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.23e-1)" "unprognostic (1.47e-1)" "unprognostic (8.87e-2)" "unprognostic (6.34e-2)" 0.9 0.7 0.1 19.1 0.1 1.9 0.9 0.0 0.2 0.5 0.1 2.4 2.9 0.5 1.1 0.8 0.5 1.7 0.5 0.1 0.1 0.7 0.7 2.8 50.6 0.3 0.1 0.5 0.2 0.1 0.1 0.2 0.3 0.6 2.2 0.0 2.6 0.3 0.3 0.7 13.2 0.6 0.1 23.6 4.7 0.2 0.6 95.4 0.8 0.1 32.5 3.7 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 113.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.7 0.1 0.0 0.0 0.0 19.1 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.4 0.0 0.1 0.0 0.0 104.4 0.0 0.0 0.0 1.4 1.3 0.7 119.1 0.8 202.7 213.6 249.2 223.4 1.8 192.1 170.4 169.5 4.5 0.8 0.8 203.1 352.4 123.9 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.3 0.1 0.6 0.2 0.9 0.0 0.0 0.0 78.9 5.6 0.0 0.0 1.2 0.0 1.0 1.0 0.2 1.5 0.0 0.0 0.0 0.0 31.2 0.7 0.0 0.0 0.0 0.1 0.1 0.6 0.0 2.7 0.0 0.0 1.9 0.9 2.0 0.0 0.0 0.0 1.4 0.2 5.3 0.0 0.0 0.0 0.0 2.7 7.4 0.0 0.0 3.4 5.4 0.0 2.5 0.0 4.1 0.0 0.0 0.1 0.1 0.0 19.8 0.0 0.0 0.3 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.5 3.7 0.3 86.8 0.0 0.3 0.0 SKA1 "C18orf24, MGC10200" ENSG00000154839 "Spindle and kinetochore associated complex subunit 1" Q96BD8 18 50375040-50394168 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.0;lymphoid tissue: 4.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3;Extravillous trophoblasts: 9.2;Plasma cells: 10.0;Spermatocytes: 16.7;Spermatogonia: 13.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "Karpas-707: 82.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA045495 Approved Approved Microtubules NA Yes "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "HPA045495: AB_10960405" "unprognostic (2.18e-2)" "unprognostic (7.85e-3)" "unprognostic (7.66e-3)" "unprognostic (5.93e-3)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (9.60e-8)" "unprognostic (1.03e-3)" "unprognostic (1.16e-2)" "unprognostic (1.20e-2)" "unprognostic (1.18e-4)" "unprognostic (3.91e-3)" "unprognostic (0.00e+0)" "unprognostic (4.50e-3)" "unprognostic (4.66e-2)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" 0.4 0.5 0.9 2.2 0.8 12.0 0.3 2.5 1.1 0.4 0.8 1.6 1.7 0.6 0.2 2.5 0.2 0.3 0.2 1.0 0.5 0.1 0.3 0.4 4.9 1.0 0.9 0.2 0.4 0.1 0.0 1.6 1.2 0.3 2.1 0.4 0.3 0.1 0.6 1.5 1.4 1.1 0.3 1.3 0.8 4.3 1.3 3.6 0.3 0.2 4.8 0.5 0.7 2.4 27.1 10.8 18.6 19.0 1.2 2.1 9.9 30.7 10.6 29.9 28.5 4.7 10.6 21.1 7.6 11.0 25.8 23.6 25.6 13.0 31.4 34.6 2.6 27.0 5.5 18.3 2.3 42.2 26.8 1.5 1.3 20.7 8.2 3.2 20.0 20.0 30.8 82.6 26.4 5.7 34.6 12.1 14.2 6.5 6.4 17.3 18.3 23.5 8.5 1.6 13.7 10.9 17.2 9.9 13.6 15.3 11.4 20.2 10.1 32.8 19.0 12.8 31.8 27.5 41.6 32.4 18.2 34.9 33.3 0.9 0.4 0.1 0.1 0.1 0.1 0.2 0.1 0.5 0.2 0.3 0.2 0.1 0.6 0.6 0.2 0.2 0.4 0.2 0.9 0.8 2.5 1.1 1.0 0.5 1.0 0.9 1.2 0.3 1.3 2.4 0.2 0.0 2.2 0.0 2.8 1.0 0.2 0.4 0.0 0.4 0.7 0.6 0.4 0.0 0.8 0.0 2.1 4.4 0.7 1.6 0.0 0.1 4.5 0.5 0.7 0.4 1.2 22.3 0.2 0.0 9.2 1.4 0.5 1.1 0.0 4.9 2.2 0.1 5.3 0.0 0.1 2.7 0.0 0.8 0.9 2.2 0.3 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 1.1 0.0 10.0 0.4 0.1 0.1 0.2 0.8 0.0 0.2 1.4 16.7 13.5 3.7 0.3 1.5 1.4 0.5 3.4 1.0 SKA2 "FAM33A, FLJ12758" ENSG00000182628 "Spindle and kinetochore associated complex subunit 2" Q8WVK7 17 59109857-59155260 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059235 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA059235: AB_2683953" "unprognostic (2.67e-1)" "unprognostic (6.42e-3)" "unprognostic (9.69e-3)" "unprognostic (5.93e-3)" "unprognostic (2.07e-1)" "unprognostic (4.44e-2)" "unprognostic (7.70e-3)" "unprognostic (9.81e-2)" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (3.96e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.59e-1)" "unprognostic (1.39e-1)" "unprognostic (4.75e-3)" "unprognostic (1.05e-1)" 19.9 12.6 30.8 20.1 33.4 24.2 11.8 43.3 39.5 18.4 29.1 22.1 18.8 20.3 12.5 24.4 18.1 13.0 34.5 27.8 36.3 21.9 22.4 16.1 33.6 34.3 37.6 16.7 11.5 26.1 14.9 22.9 34.3 16.3 20.0 44.4 10.9 19.9 12.6 13.9 16.8 24.6 37.2 15.8 18.3 12.5 34.4 53.7 25.5 20.4 28.5 20.3 18.1 38.3 217.6 78.6 249.4 85.6 32.4 24.5 76.8 107.1 102.8 163.1 182.5 120.2 122.6 114.1 118.8 87.0 124.3 90.9 162.9 149.3 231.0 197.8 127.4 179.4 142.2 75.1 36.8 142.3 112.5 35.6 63.1 104.8 84.5 64.4 77.2 127.3 114.3 164.5 117.1 297.7 215.4 71.9 66.6 238.3 145.1 114.0 281.3 81.0 121.4 93.2 112.3 96.2 119.1 53.8 66.9 165.4 179.2 112.0 68.0 160.5 153.4 130.5 244.8 111.7 255.6 135.9 85.4 105.3 117.6 26.7 13.1 17.2 18.7 23.5 14.4 18.4 25.6 24.1 15.4 13.7 19.8 22.4 2.4 22.9 38.3 18.3 48.3 12.8 30.8 33.4 43.3 39.5 27.8 36.3 34.3 37.6 34.3 37.2 34.4 38.3 24.8 25.6 18.2 23.2 24.6 21.4 21.6 49.2 25.6 36.1 10.8 17.1 46.3 12.8 26.7 9.2 25.0 62.6 25.8 16.1 39.2 38.3 20.8 22.4 30.2 26.9 10.3 96.8 10.9 25.2 61.7 26.9 30.5 21.0 18.3 26.6 25.4 33.0 46.3 50.5 20.1 23.0 14.2 37.0 22.6 9.4 27.1 28.2 23.2 15.0 42.9 49.3 39.1 15.1 26.3 31.9 24.7 25.6 52.0 8.9 12.8 32.1 26.8 39.4 0.0 13.8 41.5 38.8 30.7 34.1 13.5 30.9 35.0 33.8 35.2 18.9 SKA3 "C13orf3, MGC4832, RAMA1" ENSG00000165480 "Spindle and kinetochore associated complex subunit 3" Q8IX90 13 21153595-21176552 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.1;testis: 6.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Extravillous trophoblasts: 21.0;Spermatocytes: 21.7;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039272, HPA039356, HPA061534" Approved Supported "Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle" "Centrosome, Cytosol" "HPA039272: AB_10805359, HPA039356: AB_10805475, HPA061534: " "unprognostic (3.46e-2)" "unprognostic (7.21e-2)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (9.73e-6)" "unprognostic (2.03e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.39e-2)" "unprognostic (0.00e+0)" "unprognostic (2.24e-3)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.2 2.5 0.2 4.7 0.8 0.1 0.3 0.2 0.0 1.7 1.0 0.5 0.0 1.9 0.2 0.4 0.0 0.5 0.2 0.1 0.2 0.2 4.3 0.2 0.2 0.0 0.0 0.0 0.0 1.6 0.2 0.0 3.0 0.0 0.2 0.0 0.0 1.8 2.1 1.1 0.2 0.7 1.0 6.3 0.3 12.1 0.1 0.1 3.7 0.4 0.5 0.2 26.1 13.0 25.8 20.5 0.9 5.1 19.1 35.0 14.8 42.1 28.7 23.4 27.8 35.6 10.0 19.3 18.5 24.4 34.4 15.2 54.7 30.3 15.9 47.3 7.7 12.7 0.0 39.5 17.7 1.5 1.0 34.9 15.4 4.2 20.7 30.6 26.3 14.2 33.9 21.0 60.7 37.8 27.9 42.8 23.8 36.5 50.3 15.8 12.2 9.9 30.1 11.1 11.8 17.1 8.1 17.9 15.3 33.5 8.7 16.0 23.8 17.0 43.9 9.0 19.7 34.5 4.4 31.1 51.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.2 0.2 0.1 0.3 0.5 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.4 0.0 0.0 0.0 2.6 2.0 0.7 2.4 0.0 0.1 0.9 0.8 0.8 0.0 1.8 0.0 0.0 8.7 1.0 2.1 0.0 1.2 6.3 2.8 0.9 1.4 0.0 12.8 0.8 1.3 21.0 2.1 1.5 1.6 0.0 5.8 1.8 0.4 5.5 0.0 0.6 1.8 2.0 1.9 2.9 7.7 1.5 1.6 0.0 1.9 0.8 0.3 3.1 0.0 0.2 1.0 1.6 1.2 8.5 0.3 0.4 0.6 2.0 0.4 0.0 0.3 2.3 21.7 18.2 5.8 2.8 2.2 1.2 0.5 5.0 0.7 SKP2 "FBL1, FBXL1, p45" ENSG00000145604 "S-phase kinase associated protein 2" Q13309 5 36151989-36196849 "Cancer-related genes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 37.9" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 134.4;Extravillous trophoblasts: 227.3;Syncytiotrophoblasts: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 274.7;RH-30: 286.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013491, CAB013533, HPA051196, HPA054633" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Cytosol" "CAB013491: AB_2533074, CAB013533: , HPA051196: AB_2681383, HPA054633: AB_2682550" "unprognostic (2.32e-2)" "unprognostic (2.87e-1)" "unprognostic (1.26e-1)" "unprognostic (5.74e-2)" "unprognostic (9.56e-2)" "unprognostic (1.52e-2)" "unprognostic (1.21e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.72e-7)" "prognostic favorable (8.57e-4)" "unprognostic (5.06e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (4.77e-15)" "unprognostic (2.50e-2)" "unprognostic (3.73e-1)" "unprognostic (1.63e-1)" "unprognostic (2.19e-1)" 4.9 4.0 3.6 5.8 3.9 11.4 4.9 4.7 4.5 5.9 3.9 6.1 6.3 4.7 4.3 8.3 5.1 2.9 2.5 3.9 3.1 2.3 9.8 4.2 7.9 3.7 3.5 5.2 3.8 2.5 4.0 37.9 3.9 4.0 6.1 4.6 4.0 3.7 2.2 5.7 6.5 4.1 3.9 5.9 4.0 2.6 3.7 12.3 3.1 1.6 8.3 4.7 5.6 5.4 25.4 14.8 35.6 54.3 15.5 20.1 274.7 31.2 25.7 89.5 48.7 83.3 22.8 43.3 10.6 20.0 13.3 28.3 53.3 46.7 71.0 19.2 46.7 23.9 51.4 47.1 6.1 44.8 11.4 18.1 12.2 16.9 8.5 7.7 24.2 40.2 37.9 9.1 31.9 16.4 58.9 26.8 51.5 23.8 24.2 53.7 286.7 28.3 7.2 28.1 45.5 46.8 94.3 27.4 14.1 32.2 22.7 33.3 8.0 31.4 36.1 13.5 24.5 12.4 13.1 50.8 15.2 61.3 21.9 9.2 6.6 13.4 4.2 6.1 6.9 5.2 4.7 4.5 14.0 6.0 6.4 4.6 1.1 6.2 3.2 3.5 4.8 4.7 3.6 3.9 4.7 4.5 3.9 3.1 3.7 3.5 3.9 3.9 3.7 5.4 4.4 22.4 8.9 11.8 8.7 3.7 2.4 7.1 12.0 8.2 3.6 4.2 1.3 1.5 1.7 1.8 10.4 134.4 7.4 2.4 1.9 2.4 0.7 5.2 6.5 6.5 3.0 14.1 22.4 2.9 227.3 11.6 7.1 2.4 2.5 20.9 1.8 11.9 35.0 0.0 13.1 6.0 4.1 9.3 3.1 0.3 4.1 5.3 1.8 12.2 7.6 2.5 9.2 11.6 29.5 2.6 3.4 6.4 10.9 1.0 3.2 1.4 6.2 6.8 0.0 11.5 4.1 1.4 6.4 19.8 4.0 83.9 5.6 11.8 9.6 1.2 SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 97.4;lymphoid tissue: 156.6" "Cell type enhanced" "Detected in many" "dendritic cells: 224.2;Hofbauer cells: 67.4;Kupffer cells: 199.4;Macrophages: 154.2;NK-cells: 109.2;Plasma cells: 83.0;T-cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 47.9;JURKAT: 201.5;Karpas-707: 129.2;MOLT-4: 35.8;U-266/84: 76.1;U-937: 55.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane, Cytosol" "HPA012296: AB_1856946, HPA074192: AB_2686673" "unprognostic (1.19e-2)" "unprognostic (6.29e-3)" "unprognostic (2.73e-3)" "unprognostic (6.07e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (9.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.66e-1)" "unprognostic (3.05e-2)" "unprognostic (8.60e-2)" "unprognostic (1.65e-1)" 25.2 13.1 9.5 82.9 6.4 97.4 9.5 6.1 11.5 11.1 8.2 10.8 7.9 5.2 2.9 9.4 7.0 20.9 5.2 8.2 9.1 6.4 16.9 25.9 78.6 12.0 8.4 3.0 5.8 3.1 3.1 15.2 10.3 5.2 8.4 1.3 4.6 3.6 1.5 4.0 20.7 12.5 9.7 70.3 12.5 1.4 16.9 156.6 27.6 4.4 71.0 22.0 4.2 14.6 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 0.1 2.3 0.0 0.0 0.0 6.3 47.9 0.8 0.0 0.6 0.0 0.2 0.0 201.5 0.1 129.2 0.0 0.0 35.8 9.3 0.0 0.0 0.0 0.2 0.3 7.8 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.1 0.0 15.3 0.0 0.1 0.3 0.2 0.1 6.9 76.1 0.0 0.6 55.6 0.0 0.7 110.2 203.6 87.6 123.1 110.1 41.0 79.7 88.2 79.8 48.3 75.3 77.4 262.3 132.6 148.4 6.3 124.4 158.9 9.5 6.4 6.1 11.5 8.2 9.1 12.0 8.4 10.3 9.7 16.9 14.6 2.4 9.6 19.1 0.7 36.6 2.2 0.3 0.0 0.0 9.7 0.9 1.3 3.3 1.5 10.5 0.0 0.0 0.4 224.2 0.2 0.0 0.2 0.2 0.7 0.7 5.9 0.0 13.2 1.0 0.0 1.2 4.5 3.6 0.5 37.2 1.7 8.9 2.9 67.4 0.0 1.3 0.5 0.0 199.4 15.0 1.0 0.3 154.2 5.4 14.0 36.7 0.1 109.2 0.0 0.1 0.0 0.0 0.0 83.0 0.1 0.0 0.3 5.1 0.3 6.6 1.4 1.9 0.0 0.1 0.3 2.7 0.1 160.0 0.1 0.1 0.2 SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 18.3" "Cell type enhanced" "Detected in some" "dendritic cells: 97.0;Macrophages: 21.8;NK-cells: 44.3;Plasma cells: 25.8;T-cells: 59.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.5;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.5;NK-cells: 39.2;T-cells: 33.4" "Group enriched" "Detected in some" 7 "HEL: 91.2;JURKAT: 51.8" "Not detected" "Not detected" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 48: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: AB_2682246, HPA058217: AB_2683641" "unprognostic (4.16e-3)" "prognostic favorable (7.36e-4)" "unprognostic (4.52e-4)" "unprognostic (2.30e-6)" "unprognostic (3.37e-2)" "unprognostic (3.79e-3)" "unprognostic (2.15e-3)" "unprognostic (1.13e-2)" "unprognostic (1.32e-2)" "unprognostic (2.84e-2)" "unprognostic (3.22e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.77e-8)" "unprognostic (8.48e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-2)" "unprognostic (6.45e-3)" 1.3 0.6 0.4 5.7 0.6 12.5 0.8 1.6 0.7 0.8 0.3 1.7 2.7 1.0 0.5 0.7 0.9 2.4 0.7 0.4 0.2 0.5 1.5 4.1 10.4 0.7 0.4 0.4 0.4 0.1 0.4 0.6 0.8 0.7 1.7 0.5 1.4 0.5 0.6 0.7 3.1 0.5 0.3 8.0 2.6 0.5 0.6 18.3 0.7 0.2 9.0 2.2 0.6 1.1 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 91.2 0.6 3.4 0.0 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 51.8 0.1 0.2 0.0 0.2 10.9 7.6 0.1 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 2.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.1 7.6 0.1 3.0 0.4 3.8 28.8 0.7 24.1 0.4 23.8 27.1 0.4 0.3 21.8 30.5 4.8 39.2 0.1 48.5 33.4 26.5 0.4 0.6 1.6 0.7 0.4 0.2 0.7 0.4 0.8 0.3 0.6 1.1 0.6 0.0 3.9 0.0 1.6 0.4 0.1 0.0 0.0 0.3 0.5 0.3 0.3 0.0 0.7 0.0 0.0 0.1 97.0 0.6 0.0 0.2 1.1 0.4 0.4 0.4 0.0 8.2 2.2 0.0 0.2 0.5 4.1 0.6 1.3 0.0 0.7 0.1 0.2 0.0 1.7 0.0 0.0 1.6 0.4 0.0 0.3 21.8 0.0 1.9 1.2 0.4 44.3 1.5 1.4 0.3 0.1 0.0 25.8 0.1 0.0 0.1 0.0 0.9 0.0 0.3 0.4 0.0 0.2 0.2 0.1 0.1 59.2 0.0 0.2 0.3 SLAIN2 "FLJ21611, KIAA1458" ENSG00000109171 "SLAIN motif family member 2" Q9P270 4 48341529-48426201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 319.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035824, HPA063599" Approved Enhanced Centrosome,Cytosol NA NA 210000 "Cluster 26: Non-specific - Mitochondria" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Centrosome Cytosol "HPA035824: AB_10602399, HPA063599: AB_2685056" "unprognostic (6.20e-2)" "unprognostic (1.80e-1)" "prognostic favorable (5.77e-4)" "prognostic favorable (7.98e-4)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "unprognostic (1.33e-3)" "unprognostic (2.58e-1)" "unprognostic (1.59e-1)" "unprognostic (2.23e-2)" "prognostic unfavorable (6.71e-4)" "unprognostic (1.57e-1)" "prognostic favorable (1.50e-4)" "unprognostic (1.75e-1)" "unprognostic (5.72e-2)" "unprognostic (1.85e-1)" "unprognostic (8.00e-2)" 24.9 12.6 7.0 14.6 6.6 15.5 17.0 10.5 9.0 21.4 9.0 27.3 13.4 23.6 18.6 38.7 25.7 18.5 40.6 6.1 7.2 18.6 26.7 21.0 16.5 6.9 7.1 22.2 15.1 29.6 7.8 22.2 6.8 25.8 24.0 15.8 19.1 30.2 71.8 32.5 16.3 35.4 6.0 16.3 18.2 40.3 8.1 24.4 20.0 98.8 21.0 26.3 21.9 8.5 32.8 12.7 22.2 22.0 33.9 41.6 15.6 49.3 62.3 43.0 44.5 12.6 26.8 19.4 29.7 56.7 76.7 21.2 91.5 46.1 75.6 16.1 9.5 34.1 17.5 14.4 36.5 31.5 33.4 35.4 67.1 50.0 58.0 32.2 25.8 17.1 22.3 21.1 43.7 16.5 36.4 25.9 9.4 25.7 18.2 20.6 43.1 12.4 38.0 35.4 14.7 18.7 20.0 14.8 21.2 20.4 18.6 22.2 33.0 46.8 44.2 29.9 50.5 28.6 32.1 16.3 36.8 35.2 34.5 9.5 6.5 7.7 6.6 4.7 7.2 5.1 8.1 9.9 6.6 7.5 6.6 7.1 5.8 8.8 7.3 2.3 5.7 3.6 7.0 6.6 10.5 9.0 6.1 7.2 6.9 7.1 6.8 6.0 8.1 8.5 37.2 54.5 38.7 43.8 27.9 84.2 50.6 32.6 38.7 15.8 26.5 19.4 79.6 18.6 32.3 27.6 14.6 29.3 31.7 35.0 21.5 29.9 162.4 145.1 64.7 28.8 25.2 16.6 47.0 34.9 29.1 31.9 28.5 57.4 21.6 20.3 21.8 33.0 21.6 35.3 47.3 34.5 22.4 20.5 31.0 319.2 27.4 29.2 19.6 38.4 37.5 20.7 28.8 54.3 43.1 32.2 27.9 36.9 26.2 53.9 23.4 26.4 85.1 41.0 32.9 54.1 43.1 98.7 48.8 55.0 91.5 75.5 35.0 32.8 25.6 58.3 SLAMF1 "CD150, SLAM" ENSG00000117090 "Signaling lymphocytic activation molecule family member 1" Q13291 1 160608106-160647295 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 76.6" "Cell type enhanced" "Detected in some" "B-cells: 29.8;Melanocytes: 14.2;monocytes: 22.9;Plasma cells: 49.2;T-cells: 35.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 66.3" "Group enriched" "Detected in many" 10 "B-cells: 22.7;T-cells: 66.3" "Cell line enriched" "Detected in some" 104 "HDLM-2: 195.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002438, HPA069319" Enhanced "Secreted to blood" NA NA 350000 "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB002438: AB_564011, HPA069319: AB_2732129" "unprognostic (2.99e-3)" "unprognostic (3.33e-4)" "unprognostic (2.93e-4)" "unprognostic (1.38e-4)" "unprognostic (5.87e-2)" "unprognostic (6.06e-5)" "unprognostic (1.64e-2)" "unprognostic (1.70e-3)" "unprognostic (1.69e-2)" "unprognostic (2.74e-4)" "unprognostic (6.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.24e-7)" "unprognostic (2.46e-1)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.18e-2)" 1.1 0.5 0.0 13.6 0.0 6.6 1.6 0.0 0.1 1.1 0.3 2.6 3.7 0.4 0.1 1.4 0.4 2.3 1.1 0.0 0.0 0.9 0.9 2.1 21.6 0.3 0.0 0.4 0.3 0.1 0.1 3.0 0.1 0.6 3.0 0.0 1.7 0.3 0.3 0.7 3.9 0.9 0.1 6.7 3.9 0.2 0.1 76.6 0.6 0.0 19.1 8.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 195.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.4 0.0 1.8 0.0 0.1 0.2 0.0 10.7 0.0 66.3 16.5 46.3 33.0 0.3 22.7 17.5 4.4 0.6 0.0 0.1 4.4 61.7 9.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 1.4 0.0 5.2 0.0 29.8 2.0 0.1 0.0 0.0 0.0 0.7 0.3 0.3 0.0 0.6 1.8 0.0 0.0 4.8 0.0 0.0 0.0 4.1 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 1.2 0.5 0.0 1.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.8 10.7 8.5 0.0 5.2 14.2 1.0 22.9 0.0 0.0 0.5 0.1 0.0 0.0 0.0 49.2 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.8 0.1 0.1 0.0 1.7 0.1 35.6 0.0 0.1 0.1 SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692731-1712344 "Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 263.6;Spermatogonia: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli, Cytosol" "HPA019254: AB_1856951, HPA061670: AB_2684581" "unprognostic (1.81e-2)" "unprognostic (6.80e-3)" "unprognostic (2.05e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (2.29e-5)" "unprognostic (5.53e-2)" "unprognostic (1.94e-2)" "unprognostic (1.13e-2)" "unprognostic (9.81e-3)" "unprognostic (9.55e-3)" "unprognostic (4.58e-2)" "unprognostic (7.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.44e-1)" "unprognostic (7.07e-2)" 29.9 26.4 38.6 37.6 40.2 114.2 26.7 38.0 65.7 28.4 34.4 30.6 23.9 27.3 32.9 35.9 27.6 21.9 18.4 40.9 43.6 35.1 33.9 27.2 71.7 36.4 39.1 28.0 24.4 24.0 26.7 42.0 39.3 22.8 30.6 17.1 25.6 25.3 22.6 37.7 25.6 28.8 37.7 28.3 26.9 63.1 41.8 53.5 27.3 19.2 69.5 35.0 28.0 41.1 132.7 53.9 76.6 80.7 65.3 70.0 81.9 120.1 92.5 131.4 133.8 120.3 144.7 180.6 67.4 96.0 150.9 77.8 147.0 103.0 154.1 75.4 98.5 215.9 63.3 123.6 82.6 208.3 102.8 55.0 84.7 98.1 67.3 74.4 76.5 108.8 172.7 170.3 163.2 52.8 314.6 200.6 97.4 136.7 108.6 241.1 126.3 105.3 131.0 99.5 86.1 69.3 95.4 59.6 69.5 96.8 99.0 127.7 66.3 108.0 63.8 116.1 180.4 107.4 192.2 428.3 99.6 176.0 106.0 25.7 65.4 47.5 47.1 49.7 43.3 51.6 59.7 64.8 50.6 37.8 50.6 49.6 95.8 46.3 44.8 42.2 77.9 75.4 38.6 40.2 38.0 65.7 40.9 43.6 36.4 39.1 39.3 37.7 41.8 41.1 35.2 16.0 18.8 7.2 96.3 105.2 96.3 38.8 61.5 19.4 35.9 34.0 8.2 27.1 23.6 36.8 25.0 166.3 80.5 28.8 107.6 50.6 75.9 38.8 34.9 36.1 35.9 146.0 14.6 31.3 51.8 49.1 53.5 55.5 23.5 45.9 30.0 27.0 81.3 25.2 15.1 33.6 44.7 36.8 58.6 41.6 44.1 60.3 65.8 6.5 64.4 27.4 43.3 9.0 14.4 38.7 25.3 44.0 94.2 88.6 22.5 55.4 16.3 13.6 13.1 46.3 43.8 263.6 294.0 84.1 105.8 44.7 96.6 33.2 44.1 76.5 SLC10A3 "DXS253E, P3" ENSG00000126903 "Solute carrier family 10 member 3" P09131 X 154487306-154490690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 63.6;Syncytiotrophoblasts: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "basophil: 218.6" "Lineage enriched" "Detected in all" 17 "granulocytes: 218.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021656 Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" "Intermediate filaments" "HPA021656: AB_1856955" "unprognostic (1.60e-1)" "prognostic favorable (4.53e-4)" "prognostic unfavorable (4.15e-5)" "unprognostic (8.00e-3)" "prognostic unfavorable (9.97e-4)" "unprognostic (5.47e-2)" "unprognostic (2.28e-3)" "unprognostic (9.76e-2)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.42e-1)" "unprognostic (2.52e-3)" "unprognostic (6.23e-2)" "unprognostic (2.99e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-2)" 23.3 22.9 6.1 13.1 6.2 34.0 21.0 6.8 7.9 27.1 5.8 22.5 13.9 29.6 18.4 31.2 22.8 21.3 23.2 5.9 6.1 20.6 10.3 22.7 15.1 7.4 6.8 40.8 22.8 9.6 18.8 21.1 7.4 22.9 8.3 2.0 17.4 15.7 18.3 42.9 18.7 13.5 6.9 19.3 18.9 8.9 8.1 9.8 20.6 9.4 11.2 31.8 26.0 7.7 66.4 27.0 7.3 38.3 25.2 27.6 48.9 49.2 29.2 32.5 32.3 25.0 31.8 51.0 91.1 46.8 41.3 55.9 24.4 24.7 8.6 32.7 11.8 15.9 36.0 20.3 47.0 19.0 24.9 34.8 28.1 29.9 15.8 28.5 22.6 8.7 17.6 48.6 21.6 90.0 10.2 17.0 5.9 32.4 54.9 16.8 19.9 38.8 24.7 24.2 6.8 12.0 29.8 55.4 13.0 8.5 17.9 15.0 29.5 38.0 23.9 89.6 63.2 34.3 35.6 52.8 40.9 39.6 20.2 218.6 4.5 21.1 12.9 6.5 9.6 5.3 8.5 9.2 3.9 5.2 6.0 5.9 6.1 8.8 5.6 9.5 6.4 6.3 6.1 6.2 6.8 7.9 5.9 6.1 7.4 6.8 7.4 6.9 8.1 7.7 13.3 3.2 7.0 2.3 21.1 22.6 27.1 15.2 50.7 2.8 13.7 11.8 4.0 15.7 7.3 18.4 6.2 49.5 17.4 22.1 7.9 17.8 3.6 13.0 14.8 15.8 10.2 11.1 1.6 19.4 63.6 21.2 13.7 21.0 12.7 15.8 16.8 2.3 19.4 3.3 1.4 15.5 4.1 8.4 19.6 1.2 27.1 22.7 3.6 1.0 13.2 3.0 23.7 1.5 1.6 20.9 16.0 13.2 19.8 14.1 17.2 10.4 6.9 1.9 6.6 12.1 14.3 1.9 2.9 45.5 27.8 103.0 24.5 5.4 11.7 23.5 SLC10A6 SOAT ENSG00000145283 "Solute carrier family 10 member 6" Q3KNW5 4 86823468-86849384 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 9.1;skin 1: 13.4" "Group enriched" "Detected in some" 5 "Early spermatids: 59.5;Late spermatids: 191.7" "Group enriched" "Detected in many" 5 "cervical cancer: 3.5;head and neck cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;BJ hTERT+: 1.2;HaCaT: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA016662 Enhanced NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "HPA016662: AB_1669899" "unprognostic (2.79e-2)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (8.31e-3)" "unprognostic (5.88e-2)" "unprognostic (8.87e-3)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-1)" "unprognostic (3.84e-4)" "unprognostic (1.54e-1)" "unprognostic (2.06e-1)" "unprognostic (9.22e-2)" "unprognostic (5.89e-4)" 5.2 0.3 0.1 0.7 0.3 0.0 2.8 0.1 0.2 3.1 0.0 0.4 0.1 0.5 0.3 9.1 0.6 1.0 0.7 0.1 0.4 0.1 0.1 0.3 0.1 0.2 0.3 0.1 0.7 0.6 0.2 0.1 0.3 0.4 0.3 0.0 1.5 0.2 0.7 13.4 0.2 1.0 0.1 0.2 0.3 4.3 0.9 0.3 1.0 1.1 1.2 0.9 4.7 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.2 0.1 0.4 0.2 0.3 0.3 0.1 0.9 0.7 9.3 0.0 0.0 6.2 0.0 13.8 0.0 0.8 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.5 1.7 1.0 2.6 0.0 0.0 2.5 0.0 0.1 0.6 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.2 191.7 1.5 0.1 0.0 2.8 0.0 0.0 0.0 3.5 4.8 0.1 0.0 0.4 1.2 0.1 0.0 0.0 0.1 0.0 0.0 0.2 1.2 1.2 0.6 6.0 24.9 0.0 0.0 0.0 0.0 0.2 SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 78.6;lymphoid tissue: 46.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 108.0;Kupffer cells: 166.8;Macrophages: 209.4;monocytes: 101.2" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.1;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.1;monocytes: 6.1" "Cell line enhanced" "Detected in some" "HEL: 1.2;HMC-1: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" 14.1 8.5 3.5 7.1 4.3 6.7 4.9 3.9 11.1 2.7 4.7 3.5 0.2 2.2 0.1 1.6 7.4 1.0 8.0 3.3 5.0 3.4 5.1 78.6 0.2 7.4 5.2 1.7 3.2 0.3 3.1 2.7 6.9 3.2 0.0 0.6 3.2 0.1 1.7 1.5 2.2 1.9 5.2 46.6 3.0 0.9 17.3 0.3 2.7 1.3 0.0 7.2 2.4 7.4 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.2 0.2 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.0 0.4 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 6.1 0.6 0.3 4.5 0.2 0.1 0.2 0.1 1.9 0.2 0.3 0.2 4.1 0.2 6.0 0.2 0.2 2.0 3.5 4.3 3.9 11.1 3.3 5.0 7.4 5.2 6.9 5.2 17.3 7.4 1.5 22.4 38.5 1.6 4.1 0.9 4.3 1.9 1.2 3.1 4.5 4.6 8.6 2.8 13.8 9.2 0.0 1.8 3.1 1.8 9.8 1.3 1.8 6.1 2.3 17.0 1.2 1.7 1.3 2.1 7.8 5.8 2.0 2.8 25.3 0.9 6.8 7.3 108.0 1.7 0.9 4.0 6.1 166.8 6.3 0.5 2.1 209.4 1.8 4.7 101.2 12.9 10.3 0.5 1.4 0.4 1.6 0.7 5.6 3.9 2.5 11.7 11.0 3.3 19.7 2.9 4.2 0.8 1.8 2.1 1.0 8.1 6.7 3.3 2.9 3.3 SLC12A2 "BSC, BSC2, NKCC1, PPP1R141" ENSG00000064651 "Solute carrier family 12 member 2" P55011 5 128083766-128189677 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 75.6" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 480.6;Oligodendrocytes: 566.6;Undifferentiated cells: 370.0" "Cancer enhanced" "Detected in all" "colorectal cancer: 54.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "OE19: 153.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020130, HPA063697" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "Plasma membrane" "HPA020130: AB_1854502, HPA063697: AB_2685094" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (4.20e-3)" "prognostic favorable (8.60e-4)" "unprognostic (3.99e-1)" "unprognostic (5.65e-3)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (3.30e-1)" "unprognostic (2.95e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.79e-1)" "unprognostic (3.88e-3)" 8.4 17.5 15.0 10.8 48.4 4.4 43.9 46.3 23.2 7.2 40.4 48.5 41.7 8.4 2.4 4.6 6.0 39.4 6.1 13.5 31.1 6.6 4.2 10.3 5.6 40.8 43.1 5.4 6.1 14.7 5.5 4.9 38.6 23.5 58.9 16.8 75.6 2.6 15.4 28.4 49.1 10.2 27.1 4.5 61.8 8.0 32.4 4.1 8.6 8.3 6.0 7.3 3.5 64.8 13.5 65.3 65.8 25.6 16.1 10.4 13.6 12.2 9.1 8.6 8.9 26.4 20.9 19.9 16.1 10.6 7.8 39.5 12.7 14.0 13.2 20.0 15.8 5.7 11.4 3.8 4.9 7.3 9.5 11.1 5.0 19.1 11.2 6.4 14.2 8.5 9.4 13.2 13.4 14.2 13.0 6.1 7.7 153.6 21.1 7.1 18.5 8.2 10.0 45.0 11.5 7.3 24.6 10.6 9.9 7.0 5.9 3.7 24.1 21.2 14.2 16.3 15.7 11.0 10.7 21.6 11.2 4.2 17.6 0.3 0.4 0.2 1.1 0.7 1.9 1.7 1.0 1.4 0.6 2.1 1.1 1.6 0.2 2.4 0.5 6.4 1.1 0.3 15.0 48.4 46.3 23.2 13.5 31.1 40.8 43.1 38.6 27.1 32.4 64.8 38.3 16.0 46.2 23.8 20.5 22.9 20.1 44.9 10.8 76.6 186.9 86.7 18.0 137.2 52.1 33.1 127.2 1.4 34.4 48.2 1.9 68.6 55.8 33.1 43.1 44.2 74.4 2.5 160.6 48.2 2.7 21.3 199.3 38.4 18.4 28.8 12.8 8.8 4.2 80.8 73.2 480.6 57.0 8.6 12.0 95.3 85.4 11.4 204.5 105.9 2.5 22.6 11.3 55.3 566.6 50.1 60.6 29.0 20.2 131.6 38.8 10.6 19.6 86.4 72.3 33.9 64.3 29.1 27.1 14.9 30.0 1.4 21.1 14.1 370.0 21.5 SLC12A8 CCC9 ENSG00000221955 "Solute carrier family 12 member 8" A0AV02 3 125082636-125212864 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 22.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Excitatory neurons: 38.4;granulocytes: 17.8;Inhibitory neurons: 27.8;Intestinal goblet cells: 36.6;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 19.6;HHSteC: 33.6;OE19: 27.6;U-2197: 67.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031123 Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "HPA031123: AB_2301872" "unprognostic (4.74e-2)" "unprognostic (1.46e-3)" "unprognostic (1.39e-1)" "unprognostic (5.91e-3)" "unprognostic (7.35e-3)" "unprognostic (1.79e-1)" "unprognostic (2.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.01e-1)" "unprognostic (7.84e-2)" "unprognostic (3.13e-2)" "unprognostic (1.13e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (7.18e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-2)" "unprognostic (1.78e-2)" 1.5 1.1 2.9 1.2 3.2 0.0 2.3 1.0 3.1 1.4 11.7 3.5 5.6 0.6 3.6 4.1 2.0 8.3 0.6 3.4 2.4 3.2 6.8 2.2 0.6 1.6 2.0 0.3 10.0 4.3 2.2 2.7 1.9 2.8 4.2 0.1 11.9 0.6 0.1 1.3 3.6 0.7 1.0 0.3 4.1 2.3 2.0 0.5 22.9 0.0 0.9 2.1 2.2 2.0 14.7 0.0 2.7 0.0 3.3 4.6 6.7 0.8 2.0 0.9 1.7 19.6 6.8 0.0 1.9 5.6 2.8 8.5 0.0 0.0 0.5 0.0 0.0 0.0 7.2 0.0 33.6 0.0 1.0 8.7 8.3 1.9 0.9 16.3 0.0 0.0 0.0 0.6 1.3 3.9 0.0 0.0 9.3 27.6 0.7 0.0 0.2 0.0 6.8 1.3 4.2 0.0 7.0 8.4 0.1 0.9 15.6 0.4 0.2 0.2 1.3 67.9 0.0 0.1 1.9 5.0 3.3 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.2 1.0 3.1 3.4 2.4 1.6 2.0 1.9 1.0 2.0 2.0 0.2 0.0 0.5 7.2 0.1 1.0 1.3 3.3 3.4 0.0 5.6 4.3 1.1 2.8 2.5 23.9 0.0 0.5 0.1 1.6 0.0 3.9 0.3 0.8 1.4 0.3 5.4 0.0 38.4 3.5 6.5 2.1 7.7 2.7 17.8 1.8 0.0 9.4 0.9 0.0 27.8 36.6 0.0 0.0 0.7 0.5 0.0 0.5 0.0 7.5 2.1 0.0 1.0 31.7 2.0 2.9 3.4 0.0 0.2 6.2 2.6 1.5 0.4 0.0 0.0 0.2 0.7 0.6 0.4 4.3 0.3 3.0 0.8 0.1 5.6 1.0 SLC13A2 NaDC-1 ENSG00000007216 "Solute carrier family 13 member 2" Q13183 17 28473293-28497781 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 119.6;kidney: 38.2;salivary gland: 44.9" "Group enriched" "Detected in some" 6 "Proximal enterocytes: 290.2;Proximal tubular cells: 97.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014963 Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA014963: AB_1857096" "unprognostic (8.47e-2)" "unprognostic (7.63e-3)" "unprognostic (4.36e-3)" "unprognostic (2.06e-1)" "unprognostic (2.36e-3)" "unprognostic (3.06e-1)" "unprognostic (2.28e-4)" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (1.00e-2)" "prognostic favorable (9.00e-4)" "unprognostic (2.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.50e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.7 6.1 119.6 0.0 3.0 0.0 0.0 6.8 0.0 0.0 0.0 38.2 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.8 44.9 11.4 0.0 3.1 90.8 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.0 13.7 10.9 0.6 27.1 1.6 3.7 12.5 0.0 0.7 29.3 9.8 0.7 0.0 0.0 0.0 0.2 4.8 0.0 0.1 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 31.4 0.0 0.0 0.4 0.0 0.0 0.7 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 15.7 0.0 0.0 0.0 290.2 97.8 0.3 0.4 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.5 0.0 25.8 0.5 SLC14A1 "HsT1341, JK, RACH1, RACH2" ENSG00000141469 "Solute carrier family 14 member 1 (Kidd blood group)" Q13336 18 45687025-45752520 "Blood group antigen proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;prostate: 78.3;urinary bladder: 90.9" "Group enriched" "Detected in many" 7 "Adipocytes: 136.6;Astrocytes: 228.5;Basal prostatic cells: 313.4;Erythroid cells: 102.5;Prostatic glandular cells: 192.6;Urothelial cells: 249.9" "Group enriched" "Detected in many" 5 "glioma: 5.3;prostate cancer: 8.6;urothelial cancer: 16.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 4.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "GAMG: 273.4;RT4: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059570, HPA077233" Approved Supported "Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA059570: AB_2684066, HPA077233: " "unprognostic (2.04e-1)" "unprognostic (2.56e-3)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-2)" "unprognostic (1.84e-2)" "unprognostic (1.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.17e-2)" "unprognostic (9.99e-2)" "unprognostic (2.69e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (9.09e-2)" "unprognostic (6.93e-2)" 3.4 1.6 70.2 1.0 97.1 15.2 2.0 110.5 53.6 3.6 24.9 1.7 1.3 0.5 0.7 0.4 0.3 10.1 23.7 60.5 96.0 37.9 1.1 4.3 2.3 109.4 131.0 0.3 1.7 0.9 1.0 1.6 114.2 78.3 1.3 0.3 2.3 3.0 3.9 4.1 3.4 0.5 97.7 4.6 1.8 0.2 133.8 7.7 6.4 7.8 2.3 90.9 2.2 104.6 0.0 0.4 0.0 0.1 0.0 0.2 0.7 0.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 273.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 38.3 0.0 0.2 0.0 0.2 0.3 0.1 0.9 0.3 0.0 0.3 0.2 0.0 0.0 0.2 3.0 113.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.8 0.5 0.9 0.1 4.1 0.2 0.1 2.7 1.3 1.3 0.0 0.0 1.1 0.8 0.0 0.0 0.3 0.9 0.9 0.0 0.3 0.2 1.5 0.0 0.9 0.0 0.1 4.1 0.6 70.2 97.1 110.5 53.6 60.5 96.0 109.4 131.0 114.2 97.7 133.8 104.6 136.6 0.0 0.6 228.5 3.1 0.3 313.4 0.1 0.6 0.3 5.4 1.5 10.9 5.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.6 0.0 0.1 28.7 0.0 102.5 0.6 0.2 0.1 3.8 0.0 0.1 0.0 0.2 21.4 0.3 0.1 0.0 0.7 0.2 18.3 0.6 0.3 0.4 0.0 2.0 12.4 5.6 0.1 0.0 5.2 3.5 0.7 0.3 0.0 1.2 2.1 192.6 0.0 0.0 0.0 0.2 0.0 1.7 3.7 0.1 0.2 0.2 0.4 0.0 6.1 0.1 0.0 249.9 SLC16A14 "FLJ30794, MCT14" ENSG00000163053 "Solute carrier family 16 member 14" Q7RTX9 2 230034982-230068993 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.6" "Cell type enhanced" "Detected in many" "Adipocytes: 17.0;Excitatory neurons: 18.5;Inhibitory neurons: 21.1;Microglial cells: 45.0;Oligodendrocyte precursor cells: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "eosinophil: 11.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 11.3" "Cell line enhanced" "Detected in many" "HL-60: 24.2;Karpas-707: 15.2;REH: 19.5;RPMI-8226: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040518 Uncertain Approved "Endoplasmic reticulum" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA040518: AB_10794877" "unprognostic (2.99e-1)" "unprognostic (1.74e-1)" "unprognostic (2.63e-1)" "unprognostic (1.74e-3)" "unprognostic (2.20e-3)" "unprognostic (2.01e-1)" "unprognostic (4.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.15e-1)" "unprognostic (5.70e-3)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.03e-3)" "unprognostic (3.51e-1)" "unprognostic (2.39e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" 4.6 3.9 7.9 1.7 7.2 5.6 3.2 8.9 7.7 5.0 2.4 3.7 1.0 3.9 2.3 4.0 3.1 2.8 2.4 7.1 7.2 2.3 2.0 1.9 1.3 5.2 6.1 7.3 0.8 7.0 1.4 1.2 4.7 4.5 4.0 2.5 18.6 3.6 1.0 11.0 1.3 3.8 3.8 5.9 1.4 1.2 9.4 2.2 1.5 2.0 1.5 2.0 2.7 4.7 2.9 1.6 1.3 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.4 0.0 0.5 0.0 0.3 0.1 0.0 0.5 5.1 1.4 0.1 0.0 9.7 0.2 3.1 0.0 0.3 24.2 0.0 0.5 3.6 0.0 0.0 3.9 0.2 4.7 0.0 15.2 0.3 0.0 2.4 2.7 1.0 0.3 2.7 19.5 0.0 17.3 5.6 2.6 6.3 2.3 4.9 0.0 0.1 0.1 7.7 1.9 0.0 0.0 1.3 3.3 2.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 11.3 0.4 0.0 0.3 0.3 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.9 7.2 8.9 7.7 7.1 7.2 5.2 6.1 4.7 3.8 9.4 4.7 17.0 0.0 0.0 2.3 1.5 2.5 0.5 1.9 3.4 3.3 1.2 0.8 3.9 0.0 3.5 0.0 2.1 0.0 0.1 1.8 0.0 0.8 0.0 0.5 2.6 10.8 3.6 0.0 18.5 0.6 0.0 2.3 0.0 0.3 0.0 0.2 4.2 2.1 0.1 3.3 21.1 0.3 4.1 0.3 0.6 0.0 1.2 0.1 1.8 45.0 0.0 1.9 0.0 13.6 1.8 0.8 1.0 3.0 8.4 0.9 0.0 0.3 1.6 1.6 0.0 0.5 1.4 0.2 0.2 6.8 4.7 0.3 1.4 8.4 1.3 0.3 SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 124.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 71.7;Proximal tubular cells: 192.3" "Cancer enhanced" "Detected in all" "renal cancer: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 20.4;BJ hTERT+: 20.7;CAPAN-2: 30.8;HHSteC: 19.2;hTERT-RPE1: 42.6;SK-MEL-30: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: AB_2679892, HPA060163: " "unprognostic (2.04e-1)" "unprognostic (1.69e-1)" "unprognostic (2.56e-1)" "unprognostic (2.77e-3)" "unprognostic (1.53e-1)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.70e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.69e-4)" "unprognostic (3.68e-2)" "unprognostic (9.16e-2)" "unprognostic (1.71e-2)" "unprognostic (9.46e-2)" 4.9 2.9 2.7 4.6 3.1 1.0 6.9 5.8 4.4 4.2 15.4 3.6 9.5 3.0 22.4 2.7 4.0 13.7 4.6 3.5 4.1 124.1 16.3 9.2 3.4 4.1 3.1 21.4 0.9 0.4 3.8 28.6 3.9 3.8 1.6 2.3 3.6 5.8 1.3 1.3 11.4 3.4 4.1 2.7 2.7 5.2 3.0 0.6 8.5 3.9 1.1 7.9 3.5 4.2 0.4 9.8 2.3 2.7 6.3 12.9 20.4 5.3 20.7 1.8 5.3 3.1 30.8 0.6 5.7 17.1 0.1 0.5 0.1 1.9 1.9 0.5 2.5 0.5 2.7 3.3 19.2 0.9 0.5 10.0 0.3 3.0 0.2 42.6 4.1 0.8 0.5 1.2 3.3 1.0 0.4 0.6 0.9 0.0 0.3 0.2 1.3 0.1 3.7 0.4 1.2 0.9 0.6 9.8 30.6 9.0 0.7 0.1 0.4 1.4 0.7 0.3 1.5 0.5 0.1 1.6 1.1 0.4 6.1 0.0 0.2 0.1 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 2.7 3.1 5.8 4.4 3.5 4.1 4.1 3.1 3.9 4.1 3.0 4.2 1.9 12.8 20.8 2.3 5.8 3.1 6.1 11.2 1.2 11.5 14.7 6.5 1.1 11.5 6.8 71.7 6.2 39.5 5.8 0.9 3.9 2.7 0.5 3.3 6.8 4.6 3.5 2.7 8.2 0.9 34.6 18.2 1.5 3.3 5.1 5.2 4.2 5.0 4.2 3.3 7.1 0.9 4.1 1.6 3.0 2.2 18.0 1.8 10.6 15.0 1.8 2.4 9.2 2.5 4.7 1.9 1.2 11.7 1.2 3.1 38.4 192.3 3.5 20.1 0.0 4.5 5.4 3.4 1.9 0.5 3.7 35.2 3.9 7.0 1.4 7.2 SLC18A1 "CGAT, VAT1, VMAT1" ENSG00000036565 "Solute carrier family 18 member A1" P54219 8 20144855-20183206 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "adrenal gland: 25.1" "Cell type enriched" "Detected in some" 27 "Enteroendocrine cells: 139.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.8" "Region enriched" "Detected in single" 19 "midbrain: 3.9" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 19 "monocytes: 2.8" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 67.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA006877, HPA063797" Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA006877: AB_2667690, HPA063797: AB_2685125" "unprognostic (8.03e-4)" "unprognostic (1.02e-1)" "unprognostic (3.75e-3)" "unprognostic (3.50e-1)" "unprognostic (6.61e-2)" "unprognostic (3.09e-3)" "unprognostic (1.67e-1)" "unprognostic (2.16e-2)" "unprognostic (3.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.32e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-2)" "unprognostic (8.25e-2)" "unprognostic (4.41e-2)" "unprognostic (2.06e-1)" "unprognostic (1.05e-1)" 0.1 25.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 1.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 3.8 67.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 3.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 139.0 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 SLC18A2 "SVAT, SVMT, VMAT2" ENSG00000165646 "Solute carrier family 18 member A2" Q05940 10 117241093-117279430 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.1;cervix: 30.0" "Cell type enriched" "Detected in many" 5 "granulocytes: 636.0" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 11 "hypothalamus: 20.8;midbrain: 81.1;pons: 70.5" "Immune cell enriched" "Detected in some" 15 "basophil: 59.5" "Lineage enriched" "Detected in many" 15 "granulocytes: 59.5" "Cell line enriched" "Detected in some" 19 "HMC-1: 351.0" "Region enhanced" "Detected in many" "midbrain: 62.7" "Region enriched" "Detected in all" 4 "midbrain: 111.6" HPA073224 Enhanced Approved Vesicles,Centrosome NA NA "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Vesicles, Centrosome" "HPA073224: AB_2732222" "unprognostic (1.49e-1)" "unprognostic (2.48e-1)" "unprognostic (2.33e-3)" "unprognostic (9.00e-2)" "unprognostic (2.85e-1)" "unprognostic (5.33e-3)" "unprognostic (2.23e-1)" "unprognostic (1.71e-2)" "unprognostic (1.40e-1)" "unprognostic (4.55e-2)" "unprognostic (2.00e-1)" "unprognostic (6.06e-3)" "unprognostic (7.94e-5)" "unprognostic (2.95e-2)" "unprognostic (2.31e-1)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" 1.1 14.6 0.1 0.9 1.1 2.4 1.8 0.1 0.3 30.0 0.2 2.3 1.5 2.6 1.6 2.5 0.5 3.6 0.7 0.2 20.8 0.9 2.8 7.4 0.6 3.8 81.1 10.4 3.4 0.2 0.2 0.1 70.5 9.2 3.5 0.4 0.8 1.3 0.8 6.3 2.1 2.3 0.0 0.3 4.4 0.9 5.0 6.1 0.0 0.5 0.9 2.9 7.9 0.2 0.2 1.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.3 0.6 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.7 18.6 0.1 0.2 0.0 1.0 351.0 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 0.7 0.0 0.1 1.0 0.3 0.2 0.3 0.6 0.2 0.4 0.2 0.0 0.2 3.4 0.7 0.3 0.1 0.0 0.2 0.0 0.1 0.3 0.1 2.5 0.3 0.8 0.5 0.4 0.2 0.4 1.9 0.3 59.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.0 0.0 3.8 0.0 2.0 0.1 1.1 0.1 0.3 0.2 20.8 3.8 81.1 70.5 0.0 5.0 0.2 0.0 9.6 16.2 1.0 0.2 1.9 0.0 0.0 0.0 2.1 0.2 0.0 0.3 0.0 2.5 0.0 4.2 0.0 5.7 0.4 0.0 0.0 0.0 13.1 16.1 0.7 8.9 4.2 1.1 0.0 0.0 3.4 4.1 112.4 636.0 2.4 9.7 0.3 0.8 0.0 1.7 0.0 0.0 1.0 3.6 0.2 0.6 3.5 1.8 0.0 0.1 0.4 0.0 0.5 0.6 0.1 0.1 4.9 1.9 3.8 0.0 0.1 0.7 0.8 0.0 0.4 1.3 0.2 2.1 0.0 2.7 0.0 5.6 9.8 0.1 0.1 SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.7;breast: 28.4;placenta: 24.1" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 65.4;Syncytiotrophoblasts: 160.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 13.9;BEWO: 6.2;CACO-2: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" 46.7 0.6 5.0 1.9 3.3 1.2 28.4 4.7 4.3 0.5 1.0 2.6 9.1 0.5 0.1 0.7 0.5 5.7 0.7 3.4 4.4 2.2 13.8 4.1 0.8 5.2 4.2 0.9 1.7 0.1 0.1 24.1 5.4 0.3 1.8 2.2 1.1 0.1 0.9 1.6 5.6 0.4 4.4 0.5 0.5 0.5 5.7 0.2 0.4 0.8 0.4 1.0 0.4 4.0 0.3 0.9 0.2 0.8 13.9 0.3 6.2 0.1 0.2 0.2 0.6 20.2 0.4 0.2 0.1 0.1 4.6 0.4 0.6 0.5 0.8 0.0 1.0 0.1 1.1 0.8 1.8 0.2 0.1 3.4 0.4 0.1 0.8 0.3 0.0 0.3 0.1 0.6 0.0 1.6 0.1 0.5 3.0 0.7 0.1 0.3 0.1 0.2 0.2 0.2 0.9 0.1 0.3 1.9 0.5 2.6 0.2 0.2 0.6 0.4 0.4 4.1 0.4 0.1 0.1 0.6 1.4 0.2 0.5 6.8 0.8 1.0 0.4 0.6 0.3 0.8 0.4 0.4 0.2 1.3 0.5 0.5 3.3 2.2 0.7 1.0 0.2 0.3 5.0 3.3 4.7 4.3 3.4 4.4 5.2 4.2 5.4 4.4 5.7 4.0 0.2 9.6 5.1 2.3 0.0 0.0 0.5 0.0 0.6 5.3 0.2 0.1 0.4 5.7 0.0 1.8 0.0 65.4 0.1 5.7 1.9 4.4 0.3 0.1 0.0 2.6 1.2 0.0 0.4 0.0 7.4 3.2 0.0 0.1 0.0 0.3 0.0 13.1 5.1 0.0 0.9 1.6 0.0 0.6 0.0 0.7 0.3 0.9 0.0 25.3 0.0 0.8 0.0 4.5 0.3 0.4 1.0 0.0 0.1 0.4 9.3 3.0 0.0 0.2 0.0 1.7 1.6 0.0 0.3 0.0 0.0 160.6 0.2 0.1 6.5 0.4 SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 207.7;Cone photoreceptor cells: 70.9;Rod photoreceptor cells: 72.3" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Cell line enriched" "Detected in some" 8 "HHSteC: 21.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" 1.6 0.2 1.5 0.2 1.0 0.0 1.1 1.0 1.5 1.4 0.8 1.0 2.3 1.3 0.0 1.2 1.8 5.2 1.6 1.2 1.1 0.4 1.0 0.6 0.1 1.6 1.9 2.4 0.2 0.4 0.1 0.2 1.8 0.8 0.0 40.2 0.5 0.0 1.3 0.8 3.1 0.0 1.5 0.0 0.8 0.5 2.3 0.0 0.6 3.0 0.0 1.0 1.1 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.0 1.0 1.5 1.2 1.1 1.6 1.9 1.8 1.5 2.3 1.2 1.9 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.6 0.0 0.0 0.0 70.9 0.1 3.0 2.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.2 5.9 4.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 1.0 0.0 0.3 0.0 0.0 1.2 0.5 0.0 7.5 0.0 8.5 16.5 0.0 0.1 0.0 4.0 1.2 0.7 0.0 17.7 0.7 0.0 72.3 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 1.7 0.1 0.3 0.0 SLC22A15 FLIPT1 ENSG00000163393 "Solute carrier family 22 member 15" Q8IZD6 1 115976513-116070054 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.6;brain: 31.8" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 250.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.3;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 8 "granulocytes: 1.3;monocytes: 1.2" "Cell line enhanced" "Detected in many" "hTCEpi: 36.0;hTERT-HME1: 47.4;NB-4: 27.4;THP-1: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019785 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA019785: AB_1857011" "unprognostic (3.81e-1)" "unprognostic (1.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.01e-3)" "unprognostic (5.62e-2)" "unprognostic (5.22e-2)" "unprognostic (5.85e-5)" "unprognostic (8.91e-3)" "unprognostic (1.81e-1)" "unprognostic (4.97e-2)" "unprognostic (5.15e-2)" "unprognostic (9.06e-2)" "unprognostic (7.29e-3)" "unprognostic (8.78e-3)" "unprognostic (3.44e-1)" "unprognostic (9.97e-4)" "unprognostic (1.30e-1)" 3.2 3.1 7.8 2.3 16.5 30.6 1.7 12.3 12.0 3.1 0.9 1.3 1.0 1.1 1.3 5.2 1.5 1.9 4.7 8.6 11.6 3.4 1.1 4.9 0.9 13.3 11.6 1.1 3.1 4.2 2.7 2.0 14.3 1.9 1.7 6.7 4.5 1.6 0.6 9.4 1.9 1.0 11.6 3.4 3.5 1.1 13.1 0.5 2.8 1.0 1.1 1.7 5.0 31.8 3.0 0.2 2.1 0.0 3.7 4.4 1.5 4.7 6.9 2.8 5.0 0.0 0.5 3.3 5.0 2.3 2.4 4.5 3.6 9.7 2.7 0.0 2.3 3.2 3.7 0.5 12.3 4.9 4.3 4.5 36.0 0.1 47.4 0.2 0.0 0.0 0.1 0.0 4.7 2.7 0.0 27.4 3.0 2.8 2.3 0.0 0.0 0.1 3.9 1.6 2.2 1.9 8.1 1.7 13.8 3.1 0.4 29.4 0.0 5.0 2.7 1.0 1.2 4.8 4.8 0.4 5.3 8.0 8.1 0.3 0.8 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 1.2 0.0 0.0 0.1 7.8 16.5 12.3 12.0 8.6 11.6 13.3 11.6 14.3 11.6 13.1 31.8 0.2 0.0 13.7 46.7 2.3 2.8 3.1 3.6 5.2 3.0 0.3 0.4 7.8 0.0 3.2 5.5 10.4 0.6 0.8 0.5 1.9 1.1 1.3 2.5 0.7 0.2 8.4 0.4 44.2 0.4 0.4 4.6 4.6 1.4 1.3 0.6 1.1 0.0 2.8 8.4 33.9 0.3 0.0 9.4 0.5 0.1 0.9 6.9 1.8 9.4 8.7 1.0 1.0 53.3 250.2 1.6 1.2 0.4 0.7 1.1 0.1 0.3 5.2 2.1 0.0 0.4 1.4 0.3 0.7 5.7 3.0 0.0 1.0 1.2 0.5 1.3 SLC22A31 ENSG00000259803 "Solute carrier family 22 member 31" A6NKX4 16 89195761-89201651 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 24.5;lung: 40.6;pancreas: 33.0" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 130.7;Late spermatids: 33.6" "Cancer enhanced" "Detected in many" "lung cancer: 26.2;thyroid cancer: 20.4" "Region enriched" "Detected in many" 10 "cerebellum: 24.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 33.7;Hep G2: 28.7;NB-4: 14.7;RPMI-8226: 17.7;THP-1: 9.3" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 28: BEWO - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.71e-3)" "unprognostic (2.53e-1)" "unprognostic (5.02e-3)" "unprognostic (6.82e-2)" "unprognostic (8.20e-2)" "unprognostic (1.95e-1)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" "unprognostic (2.12e-1)" "unprognostic (2.67e-1)" "unprognostic (8.98e-2)" "unprognostic (1.09e-1)" "unprognostic (8.26e-4)" "unprognostic (2.74e-1)" "unprognostic (2.05e-1)" "unprognostic (2.72e-3)" "unprognostic (1.89e-1)" 0.2 0.8 0.0 0.2 0.4 0.9 0.1 24.5 1.0 1.1 0.0 0.5 0.4 0.2 0.0 0.1 0.9 0.0 0.3 0.0 0.1 0.8 1.2 40.6 0.1 0.5 1.1 3.1 33.0 0.1 0.5 0.0 2.5 0.6 0.0 0.0 0.4 0.1 0.0 1.8 0.6 0.0 0.3 3.6 3.3 5.2 0.3 0.0 0.4 0.0 0.0 0.2 0.5 0.5 0.0 0.1 0.0 1.6 0.0 0.0 33.7 0.1 0.0 0.0 0.0 1.3 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 28.7 3.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.5 0.0 14.7 0.8 0.3 3.4 0.0 3.7 17.7 0.0 0.0 1.4 1.0 0.0 0.0 0.0 0.1 0.3 9.3 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 24.5 1.0 0.0 0.1 0.5 1.1 2.5 0.3 0.3 0.5 0.0 6.4 130.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 19.2 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.2 0.1 1.1 0.0 8.2 0.0 0.4 0.3 0.7 0.0 0.4 0.0 0.0 0.3 0.0 33.6 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.9 3.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 SLC22A9 "FLJ23666, OAT4, OAT7, UST3" ENSG00000149742 "Solute carrier family 22 member 9" Q8IVM8 11 63369785-63410294 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "liver: 46.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 2.7;Excitatory neurons: 5.0;granulocytes: 4.5;Hepatocytes: 15.4" "Cancer enriched" "Detected in single" 166 "liver cancer: 19.3" "Region enhanced" "Detected in some" "cerebral cortex: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (2.45e-1)" "unprognostic (7.24e-2)" "unprognostic (8.86e-2)" "unprognostic (2.10e-2)" "unprognostic (1.08e-2)" "unprognostic (2.26e-1)" "unprognostic (2.17e-1)" "unprognostic (2.71e-1)" "unprognostic (3.09e-2)" 0.1 0.0 0.5 0.0 0.5 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 1.4 0.0 0.2 46.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.5 0.5 0.0 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 2.7 5.0 0.2 0.0 0.1 0.0 0.0 4.5 0.1 0.0 15.4 0.0 0.0 0.3 0.0 0.0 0.6 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 SLC24A3 ENSG00000185052 "Solute carrier family 24 member 3" Q9HC58 20 19212642-19722926 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.7" "Group enriched" "Detected in many" 9 "Astrocytes: 134.5;Inhibitory neurons: 327.0;Oligodendrocyte precursor cells: 375.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "basophil: 5.8;eosinophil: 1.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 5.8" "Cell line enriched" "Detected in some" 4 "HMC-1: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043400, HPA045497" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Cytosol "HPA043400: AB_2678462, HPA045497: AB_2679349" "unprognostic (8.74e-2)" "unprognostic (1.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.41e-1)" "unprognostic (7.40e-2)" "unprognostic (2.09e-1)" "unprognostic (2.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.04e-2)" "unprognostic (3.25e-2)" "unprognostic (1.05e-1)" "unprognostic (5.40e-2)" "unprognostic (1.21e-3)" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (6.08e-4)" "unprognostic (7.36e-3)" 10.4 3.1 16.2 4.0 11.7 1.4 4.9 13.3 56.1 17.8 2.7 10.8 3.8 28.3 24.3 20.6 20.0 13.0 1.1 81.7 18.6 1.1 0.7 5.5 1.0 13.6 19.2 14.6 0.7 7.5 1.2 3.0 9.1 10.9 5.4 7.3 4.7 17.5 40.9 7.0 5.0 29.1 10.3 2.4 3.8 1.5 34.8 1.9 3.0 16.9 2.7 8.6 8.9 5.4 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.8 13.3 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.0 18.2 0.0 0.0 0.7 0.0 75.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 9.0 0.0 0.6 17.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.2 11.7 13.3 56.1 81.7 18.6 13.6 19.2 9.1 10.3 34.8 5.4 0.2 3.2 1.1 134.5 0.1 1.1 1.1 0.4 0.0 19.1 5.0 2.3 0.4 0.0 1.3 1.8 0.0 8.5 0.1 0.3 0.0 0.1 17.0 1.2 29.8 0.4 7.7 3.4 11.8 0.0 0.3 1.9 0.0 1.6 26.6 0.1 0.4 0.0 0.6 1.7 327.0 4.1 0.0 0.0 0.7 18.3 3.7 1.1 0.0 12.2 0.0 3.1 0.0 375.5 2.4 0.2 2.8 4.1 0.4 0.8 0.4 0.0 0.0 2.2 0.0 2.7 3.0 0.5 0.8 2.9 4.1 3.4 0.4 0.1 0.7 3.8 SLC24A5 "JSX, OCA6" ENSG00000188467 "Solute carrier family 24 member 5" Q71RS6 15 48120990-48142672 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport" Albinism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 8.2" "Group enriched" "Detected in some" 7 "Early spermatids: 20.7;Melanocytes: 76.5" "Cancer enriched" "Detected in single" 162 "melanoma: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 800 "SK-MEL-30: 251.8" "Group enriched" "Detected in some" 5 "hippocampal formation: 3.0;pons and medulla: 4.1;thalamus: 1.5" "Low region specificity" "Detected in all" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (3.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.35e-1)" "unprognostic (1.92e-3)" 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.3 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.1 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 251.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.2 0.1 0.5 0.1 0.9 0.2 0.0 0.9 0.2 0.3 0.0 0.5 0.7 0.2 2.4 0.0 0.0 0.0 6.4 0.0 0.1 0.3 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 20.7 1.5 0.1 0.1 0.0 0.4 2.9 0.0 0.0 0.5 0.0 0.9 0.0 0.1 0.0 0.0 0.1 5.0 2.7 0.0 0.0 0.0 0.7 6.6 0.0 0.0 76.5 1.0 0.0 0.9 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 4.6 0.0 0.1 0.1 0.1 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 SLC25A17 PMP34 ENSG00000100372 "Solute carrier family 25 member 17" O43808 22 40769630-40819399 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052708, HPA060972" Approved Supported Peroxisomes NA NA "Cluster 6: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Peroxisomes "HPA052708: AB_2681924, HPA060972: AB_2684400" "unprognostic (2.75e-1)" "unprognostic (1.11e-3)" "unprognostic (1.91e-3)" "unprognostic (2.44e-2)" "unprognostic (2.61e-1)" "unprognostic (1.96e-2)" "unprognostic (2.85e-3)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" "unprognostic (1.63e-3)" "unprognostic (8.44e-2)" "unprognostic (2.72e-1)" "unprognostic (5.59e-2)" "unprognostic (8.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" 7.4 12.3 9.4 5.3 9.2 3.3 14.3 9.9 10.7 9.3 11.5 6.3 5.4 13.2 19.6 7.1 11.4 5.7 4.3 9.2 10.2 13.6 16.9 6.6 9.4 9.9 9.6 20.6 8.8 13.6 9.2 10.0 9.7 10.7 7.3 9.2 9.8 5.9 3.9 9.6 6.0 10.5 10.1 7.3 7.8 10.0 10.0 9.3 12.7 3.6 9.7 8.1 7.2 11.2 23.5 13.5 21.0 18.5 12.8 15.9 16.8 20.7 22.7 32.5 35.7 16.5 8.8 26.7 12.2 20.4 17.7 18.6 30.6 16.6 33.4 27.0 41.3 31.1 18.4 21.1 18.3 35.8 16.2 15.3 22.8 28.6 18.4 14.7 19.4 21.4 46.5 12.9 26.5 19.2 22.0 24.2 17.7 33.2 20.6 23.8 32.4 40.3 27.6 19.7 14.2 12.5 42.8 26.6 26.7 20.3 22.0 10.7 11.8 18.5 24.4 16.1 19.2 13.9 29.6 25.7 19.7 18.4 20.4 7.0 3.3 4.2 4.9 3.9 6.9 8.4 5.8 5.5 4.2 7.6 8.2 6.7 1.5 8.3 3.3 5.4 8.6 4.7 9.4 9.2 9.9 10.7 9.2 10.2 9.9 9.6 9.7 10.1 10.0 11.2 8.4 19.2 9.5 23.2 10.9 16.6 16.8 29.8 10.8 12.1 13.6 9.3 4.0 7.2 20.7 12.9 8.4 39.8 8.0 5.8 21.5 17.9 9.6 17.9 16.5 10.4 6.1 11.6 17.3 17.7 31.9 15.9 8.2 14.2 5.1 15.5 8.2 24.8 12.9 11.8 21.5 6.5 26.4 7.9 6.0 16.0 27.1 7.4 16.0 7.5 17.6 7.9 10.3 18.1 28.0 18.1 4.4 26.7 11.9 18.1 8.2 21.1 15.0 7.0 32.9 9.3 11.6 51.0 38.0 11.7 17.2 28.6 9.7 16.4 7.5 14.9 SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 143.8;choroid plexus: 90.7;liver: 111.5" "Group enriched" "Detected in many" 4 "Astrocytes: 195.2;Hepatocytes: 72.8" "Group enriched" "Detected in some" 5 "glioma: 10.6;liver cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.8;BEWO: 8.5" "Low region specificity" "Detected in all" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria Nucleoplasm "HPA068110: " "unprognostic (2.15e-1)" "unprognostic (6.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-2)" "unprognostic (2.72e-2)" "unprognostic (8.70e-4)" "unprognostic (1.44e-1)" "unprognostic (3.92e-2)" "unprognostic (1.67e-2)" "unprognostic (1.29e-1)" "unprognostic (5.24e-2)" "unprognostic (1.62e-1)" 14.4 1.0 130.1 0.3 132.1 0.1 7.2 116.5 141.1 2.5 90.7 2.9 0.3 2.9 0.2 0.3 3.8 0.9 2.8 119.4 123.3 1.9 111.5 1.2 0.3 121.7 129.2 1.2 1.1 0.2 1.5 0.1 112.5 7.8 0.1 1.9 0.5 0.4 6.2 1.2 1.9 0.5 106.5 4.8 1.5 4.2 143.8 0.3 0.6 4.0 0.1 0.8 1.4 110.7 0.3 0.6 2.2 0.4 3.8 0.0 8.5 0.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.5 0.7 0.0 0.0 0.0 0.3 1.0 0.3 0.3 0.5 1.5 0.3 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.3 0.0 0.4 0.1 0.5 2.0 0.9 1.4 2.9 0.8 0.0 0.1 0.4 0.8 0.3 0.2 0.4 0.7 1.6 2.5 1.0 0.1 0.1 0.3 0.2 0.3 0.9 1.2 0.0 1.8 0.2 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.1 132.1 116.5 141.1 119.4 123.3 121.7 129.2 112.5 106.5 143.8 110.7 1.0 28.9 10.3 195.2 0.3 0.0 0.3 0.1 0.6 0.6 0.3 0.0 1.5 5.7 7.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.6 0.4 0.9 1.7 0.0 10.7 2.0 0.0 0.3 4.7 0.0 0.7 6.3 8.5 3.6 72.8 0.3 0.0 3.0 0.3 0.0 4.1 0.3 0.6 0.9 3.9 0.0 10.3 0.1 2.2 1.0 13.0 11.5 0.0 0.0 2.6 0.1 4.3 0.1 0.8 15.8 3.4 0.0 2.7 2.5 4.8 5.9 0.0 0.1 1.8 2.6 2.6 0.0 0.2 SLC25A34 DKFZp781A10161 ENSG00000162461 "Solute carrier family 25 member 34" Q6PIV7 1 15736258-15741392 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "heart muscle: 14.4;intestine: 14.0;skeletal muscle: 37.8;tongue: 47.3" "Cell type enriched" "Detected in many" 5 "Proximal enterocytes: 44.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069806 Approved Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA069806: AB_2686202" "unprognostic (2.06e-1)" "unprognostic (4.72e-1)" "unprognostic (1.15e-1)" "unprognostic (2.43e-1)" "unprognostic (2.58e-1)" "unprognostic (8.08e-3)" "unprognostic (1.98e-2)" "unprognostic (9.92e-2)" "unprognostic (1.55e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-4)" "unprognostic (5.74e-2)" "unprognostic (6.10e-2)" "unprognostic (4.02e-1)" "unprognostic (1.82e-1)" "unprognostic (4.04e-2)" "unprognostic (2.40e-4)" 2.4 4.4 3.7 1.0 3.8 3.4 1.8 6.8 4.8 3.6 2.4 5.7 14.0 3.1 0.8 1.7 2.9 1.5 14.4 3.6 3.4 4.7 5.6 2.4 1.2 3.2 3.1 4.2 4.9 0.6 3.8 1.3 3.5 2.4 2.0 1.9 4.7 0.8 37.8 1.8 13.7 1.1 2.7 3.7 2.2 2.5 3.7 0.5 3.4 47.3 0.5 2.8 2.3 3.6 0.3 0.2 1.5 0.6 0.7 0.3 0.6 0.2 0.1 0.3 0.2 0.6 0.8 0.4 0.3 0.3 0.8 0.3 0.2 0.2 0.3 0.5 0.3 0.7 0.5 0.2 0.2 0.2 0.9 0.3 1.1 0.4 0.1 0.9 0.2 2.0 0.3 1.3 0.2 0.7 1.7 0.9 1.3 0.2 0.4 0.9 1.3 0.4 0.1 0.0 0.3 1.2 0.3 0.4 3.4 1.4 0.7 1.0 0.8 0.7 1.0 1.0 0.2 1.7 1.6 0.3 0.2 0.9 0.6 0.5 0.1 0.1 0.4 0.0 0.9 0.1 0.9 0.6 0.0 0.2 1.2 0.7 0.6 0.6 0.0 0.1 0.4 0.3 3.7 3.8 6.8 4.8 3.6 3.4 3.2 3.1 3.5 2.7 3.7 3.6 0.9 0.0 0.0 6.2 0.4 0.3 0.3 0.6 0.0 2.6 0.5 0.5 2.7 1.5 0.2 0.0 0.0 0.3 0.3 8.8 0.0 0.2 0.3 0.4 1.3 1.2 3.5 0.0 5.1 0.2 0.4 0.8 2.0 1.7 0.0 1.3 2.2 2.3 1.5 3.3 4.6 3.1 0.0 1.9 0.3 1.0 0.9 1.5 0.0 2.8 1.1 1.8 0.0 2.5 1.7 0.3 8.0 0.4 0.0 0.6 44.6 3.7 0.0 1.8 0.0 2.7 0.9 0.6 0.6 1.1 0.1 1.4 0.6 0.4 5.5 0.7 SLC25A35 FLJ40217 ENSG00000125434 "Solute carrier family 25 member 35" Q3KQZ1 17 8287763-8295400 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.9;Syncytiotrophoblasts: 17.4" "Cancer enhanced" "Detected in all" "endometrial cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051720 Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Mitochondria" "HPA051720: AB_2681584" "unprognostic (4.73e-2)" "unprognostic (1.36e-3)" "unprognostic (1.21e-2)" "prognostic favorable (3.37e-7)" "unprognostic (1.61e-2)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (5.27e-2)" "unprognostic (2.58e-1)" "unprognostic (8.30e-2)" "unprognostic (8.96e-3)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-6)" "unprognostic (5.31e-3)" "unprognostic (2.34e-1)" "unprognostic (1.00e-1)" "prognostic favorable (1.91e-5)" 5.7 8.3 2.9 4.9 3.9 6.1 8.6 3.5 4.4 10.0 4.6 7.7 6.1 13.4 7.6 5.4 7.1 5.2 4.8 2.9 3.2 15.0 4.6 6.8 5.0 3.9 4.0 2.9 12.2 6.1 12.8 4.1 4.1 8.7 5.3 4.5 6.4 5.2 2.2 4.5 7.7 4.1 3.3 8.9 12.5 24.5 4.4 5.2 9.1 1.5 3.5 6.0 5.0 4.2 5.0 13.5 2.4 10.0 7.5 2.9 5.5 3.2 2.8 3.4 3.7 1.6 12.4 5.8 3.3 3.7 7.1 11.0 2.8 3.8 1.9 3.2 3.6 4.8 11.1 1.9 2.7 0.7 12.8 5.9 2.1 6.5 1.2 2.5 5.4 6.8 1.4 2.0 2.9 2.7 5.3 2.7 0.8 3.4 4.4 5.8 1.6 2.6 2.6 12.6 1.2 3.0 9.2 5.4 4.1 2.4 12.2 3.6 7.6 2.3 1.7 5.6 2.7 4.3 2.9 2.1 5.9 8.6 6.1 4.1 5.6 7.6 4.0 8.8 3.3 1.9 3.7 4.3 5.7 3.6 1.3 2.5 1.1 2.8 6.5 3.0 4.1 2.5 2.9 3.9 3.5 4.4 2.9 3.2 3.9 4.0 4.1 3.3 4.4 4.2 3.1 0.0 5.4 5.2 3.6 0.8 1.5 1.4 2.8 4.3 6.3 4.1 1.0 5.7 1.8 11.0 8.4 9.2 2.1 3.8 11.7 2.8 3.8 10.2 1.9 2.8 9.0 4.6 0.5 7.1 2.3 3.0 5.1 10.6 5.1 1.3 1.8 2.8 6.7 1.7 0.7 3.0 2.0 6.4 1.5 5.5 1.5 4.2 0.0 4.7 5.8 7.9 3.1 1.0 2.5 3.2 6.0 1.2 3.7 1.9 2.4 7.3 2.0 9.0 0.0 1.1 1.2 20.9 0.8 1.9 0.3 17.4 3.2 9.1 3.1 1.9 SLC25A43 ENSG00000077713 "Solute carrier family 25 member 43" Q8WUT9 X 119399336-119454478 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 30.7;Oligodendrocyte precursor cells: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035188, HPA078530" Uncertain Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA035188: AB_10602400, HPA078530: " "unprognostic (6.05e-3)" "unprognostic (1.48e-1)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (4.99e-3)" "unprognostic (1.59e-2)" "unprognostic (3.26e-2)" "unprognostic (2.74e-2)" "unprognostic (7.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.80e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.06e-8)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "unprognostic (1.96e-2)" "unprognostic (4.92e-2)" 10.6 2.6 3.1 7.3 3.4 1.8 9.3 3.3 4.1 8.2 5.4 14.0 14.2 5.0 3.4 21.4 5.3 4.3 5.0 3.2 3.6 7.7 10.6 10.2 5.5 4.3 3.5 6.0 5.9 6.9 1.9 8.3 3.9 4.6 15.5 0.5 10.8 4.6 1.6 16.3 12.8 8.8 3.5 4.9 8.9 2.1 3.6 3.6 4.2 4.5 11.3 7.9 11.3 3.8 32.4 23.3 1.9 9.2 30.0 44.5 12.2 17.9 21.7 13.8 13.2 12.4 16.0 4.0 10.2 47.4 41.1 23.2 18.2 16.0 12.4 28.5 5.4 11.3 7.4 16.4 19.3 10.6 11.7 18.8 28.3 22.5 19.8 18.9 16.6 6.1 2.3 17.1 15.7 58.9 0.1 15.9 10.3 16.6 35.1 3.2 0.0 4.6 22.3 10.9 1.5 0.0 23.0 47.8 29.1 7.3 8.5 11.0 24.2 22.2 7.1 25.0 28.0 0.4 14.2 8.3 22.3 17.8 19.7 0.0 3.5 0.2 0.9 4.9 1.7 4.4 1.8 2.9 6.0 3.7 0.9 1.8 0.1 6.4 11.2 1.6 1.5 1.6 3.1 3.4 3.3 4.1 3.2 3.6 4.3 3.5 3.9 3.5 3.6 3.8 8.3 6.4 9.7 30.7 8.0 7.8 7.3 8.9 9.6 0.2 6.1 6.6 1.6 2.8 5.6 3.7 0.0 11.9 9.1 21.8 9.8 4.5 0.0 0.9 7.6 6.9 7.3 3.4 10.3 8.9 7.1 11.8 9.7 1.8 8.2 2.1 6.4 5.8 10.3 0.0 6.2 9.6 4.1 7.1 13.6 0.4 8.1 7.5 10.6 1.0 11.9 0.2 9.2 36.7 1.4 13.9 11.4 5.7 2.8 5.4 19.8 9.6 2.0 0.4 0.0 7.8 9.2 0.5 2.3 19.8 13.9 6.8 6.8 1.0 12.2 5.8 SLC26A2 "DTD, DTDST" ENSG00000155850 "Solute carrier family 26 member 2" P50443 5 149960758-149993455 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 212.0" "Group enriched" "Detected in many" 4 "Distal enterocytes: 2026.2;Glandular and luminal cells: 684.5;Syncytiotrophoblasts: 808.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "EFO-21: 66.1;RPTEC TERT1: 151.7;TIME: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041957, HPA058090" Enhanced Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041957: AB_10795646, HPA058090: AB_2683602" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "unprognostic (3.03e-2)" "prognostic favorable (7.29e-4)" "unprognostic (2.59e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.59e-1)" "unprognostic (5.64e-2)" "unprognostic (1.19e-1)" "unprognostic (7.43e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.70e-1)" "unprognostic (1.77e-1)" "unprognostic (8.12e-2)" "unprognostic (1.06e-1)" 5.2 30.7 2.2 7.8 2.3 2.5 9.2 9.5 3.8 6.3 4.0 212.0 12.9 9.3 22.8 10.7 5.0 5.5 2.8 2.2 3.5 4.9 1.7 7.3 4.0 3.8 3.4 4.8 3.4 37.7 7.1 34.0 3.5 12.2 189.6 20.8 35.8 18.4 3.9 7.8 16.1 9.3 3.8 3.7 3.3 4.2 3.9 4.2 4.5 3.7 5.9 4.7 3.0 3.4 9.5 8.6 10.5 17.3 12.6 8.8 2.5 8.9 8.0 7.0 8.5 44.7 5.1 7.4 66.1 9.5 16.8 6.8 10.0 20.5 12.4 6.0 6.4 9.3 6.7 5.2 9.4 17.3 15.2 9.8 11.8 11.7 15.2 17.3 16.8 9.0 2.4 7.1 29.6 3.0 6.6 9.1 3.2 3.2 13.5 9.5 16.3 3.9 151.7 41.6 3.2 8.1 15.6 3.6 27.2 8.1 7.3 10.0 80.4 16.0 11.8 14.2 10.7 5.2 7.3 4.3 14.7 20.6 23.5 4.9 0.5 0.3 0.9 0.3 1.1 0.5 0.5 0.8 0.7 0.5 0.8 0.9 0.3 1.1 1.6 0.7 1.1 0.5 2.2 2.3 9.5 3.8 2.2 3.5 3.8 3.4 3.5 3.8 3.9 3.4 47.4 44.8 11.3 3.3 8.5 4.6 13.2 22.9 7.4 17.1 23.8 14.6 7.8 7.2 24.2 33.1 16.7 219.2 11.5 2026.2 1.9 6.1 32.7 237.0 92.3 29.8 21.1 16.6 5.4 9.9 7.7 21.5 5.1 684.5 90.0 29.6 17.2 2.0 30.4 6.7 7.9 52.5 20.3 15.3 11.8 15.7 17.4 17.4 90.7 17.8 19.6 15.2 15.5 16.6 6.0 12.1 177.4 12.4 15.2 15.1 91.7 5.1 26.6 84.5 0.0 18.7 13.9 8.7 11.4 73.9 5.1 808.9 14.0 26.3 208.9 5.5 SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1120.4" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 2328.4" "Cancer enriched" "Detected in many" 14 "colorectal cancer: 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036055 Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036055: AB_10602401" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (4.02e-1)" "unprognostic (4.09e-2)" "unprognostic (3.05e-3)" "unprognostic (6.31e-2)" "unprognostic (1.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (8.85e-2)" "unprognostic (8.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.54e-2)" "unprognostic (3.58e-3)" 1.1 0.0 0.0 19.7 0.0 0.0 59.5 0.2 0.1 0.3 0.0 1120.4 576.9 0.9 15.3 0.5 0.8 17.8 0.0 0.0 0.0 0.8 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.1 878.8 0.1 0.0 129.9 0.0 0.1 118.5 15.0 0.0 0.0 1.3 0.9 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 165.9 4.2 0.0 0.3 0.0 0.0 0.0 51.4 41.7 0.3 34.3 0.0 0.0 0.0 0.0 0.0 2328.4 0.0 0.0 6.4 1.8 0.1 0.3 14.3 0.0 110.2 0.0 0.0 0.1 0.0 0.2 26.7 0.2 0.0 0.1 0.0 0.0 114.3 32.5 0.0 0.0 0.0 0.6 0.3 0.1 0.0 89.9 0.0 0.0 0.0 101.6 182.1 0.0 503.4 0.0 0.0 0.3 388.9 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 0.0 86.0 0.1 SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 157.7;liver: 288.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 265.5;Hepatocytes: 205.7;Proximal enterocytes: 81.0;Proximal tubular cells: 198.9;Respiratory ciliated cells: 70.2" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 30 "basophil: 63.5" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.5" "Cell line enhanced" "Detected in many" "A549: 50.0;HaCaT: 89.3;HL-60: 66.3;OE19: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026089 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" 4.8 16.0 1.7 2.9 2.0 6.5 13.3 1.7 3.2 1.6 9.2 18.2 11.1 0.3 65.9 2.6 10.9 2.3 0.0 2.7 2.4 157.7 288.0 1.7 1.5 0.8 1.1 0.1 7.2 4.1 12.4 17.3 0.8 5.4 16.2 3.4 0.9 1.0 0.0 1.2 21.3 0.8 0.8 0.4 1.8 0.9 2.5 0.5 4.6 0.0 1.7 3.6 1.2 0.7 0.0 50.0 0.0 0.0 0.0 0.0 0.1 0.9 0.4 0.9 1.3 26.2 6.9 0.0 0.6 1.2 0.6 89.3 22.8 0.7 2.3 36.0 27.9 37.5 43.0 23.6 0.5 66.3 25.8 0.0 2.1 0.2 0.1 0.0 0.0 16.9 11.6 0.0 0.0 8.3 1.8 44.5 1.7 101.8 1.8 0.0 0.0 1.8 4.7 45.7 40.4 2.6 8.7 1.1 0.0 1.1 4.7 22.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 21.2 0.0 63.5 0.0 0.9 0.8 0.0 0.7 0.3 0.7 0.8 0.0 0.2 0.1 0.2 0.3 2.0 0.0 0.0 0.9 0.5 1.7 2.0 1.7 3.2 2.7 2.4 0.8 1.1 0.8 0.8 2.5 0.7 0.3 0.0 1.1 0.7 2.2 1.0 1.3 8.7 1.2 1.1 1.1 0.3 0.3 0.0 13.6 9.2 0.0 265.5 1.6 17.2 11.7 0.6 0.7 9.8 0.1 0.8 4.2 8.0 4.9 2.0 7.6 0.9 1.5 0.7 6.3 0.1 3.9 205.7 16.4 1.7 6.6 18.9 10.2 3.2 0.3 0.9 0.3 1.2 0.0 1.0 0.0 0.6 1.0 0.0 0.4 1.4 26.6 0.0 0.8 3.3 81.0 198.9 70.2 1.9 0.0 0.0 1.0 4.4 4.2 5.1 0.3 54.9 4.6 0.2 25.9 4.9 SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925353-42958893 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease variant, Dystonia, Epilepsy, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 98.7;skin 1: 79.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 833.8;Erythroid cells: 520.4;Extravillous trophoblasts: 536.4;Syncytiotrophoblasts: 2482.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 241.0;CACO-2: 219.9;Hep G2: 157.4" "Low region specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane" No No 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "CAB002759: , HPA031345: AB_2673835, HPA058494: AB_2683734" "unprognostic (3.60e-2)" "unprognostic (5.85e-3)" "unprognostic (7.59e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-3)" "unprognostic (3.22e-2)" "prognostic unfavorable (3.65e-8)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.10e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (1.87e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (1.11e-1)" "unprognostic (9.49e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.05e-4)" 6.9 3.6 24.1 2.5 26.1 41.6 7.8 33.7 27.7 28.6 43.6 6.1 0.4 5.1 1.4 54.1 8.2 1.7 10.0 20.6 28.5 14.2 1.7 3.3 1.0 31.9 29.3 5.5 2.1 4.5 4.8 98.7 34.5 6.0 1.0 24.6 17.6 5.1 2.0 79.8 4.6 0.4 24.7 7.5 8.4 2.1 41.2 1.0 3.0 1.5 2.1 19.3 54.2 29.4 60.5 52.9 66.3 6.2 3.5 1.2 241.0 47.8 36.9 15.5 27.8 219.9 96.3 22.2 138.9 6.0 26.5 43.6 12.5 52.3 14.8 16.4 10.3 29.8 20.9 157.4 12.9 16.8 8.1 3.3 21.3 18.3 20.5 96.7 2.9 12.8 81.2 1.5 11.7 46.6 7.4 11.7 35.1 22.1 17.9 8.4 20.6 23.3 21.7 17.9 27.0 23.8 47.7 95.6 11.0 70.0 3.8 16.9 14.9 25.6 28.6 6.1 83.8 5.3 6.5 11.5 57.1 8.2 25.5 0.5 0.1 1.2 10.6 0.3 8.5 10.9 5.1 6.7 3.7 8.3 3.8 4.8 0.2 4.3 0.1 18.4 6.2 4.0 24.1 26.1 33.7 27.7 20.6 28.5 31.9 29.3 34.5 24.7 41.2 29.4 3.1 0.0 1.8 12.7 25.4 286.1 48.8 286.3 66.0 15.8 41.4 21.8 26.7 20.0 159.3 27.6 66.7 833.8 33.5 53.1 5.9 53.2 4.0 112.1 46.0 100.5 18.4 520.4 2.8 11.7 536.4 25.9 11.7 118.9 6.3 6.8 2.2 2.1 84.8 5.0 3.2 22.4 65.1 1.6 34.2 0.3 7.8 5.0 21.4 71.2 36.0 350.1 18.6 8.0 9.9 120.3 51.9 14.7 11.6 31.2 1.9 2.2 118.1 32.1 0.0 9.8 32.1 0.1 2.4 99.1 238.3 2482.5 20.8 5.5 11.8 105.8 SLC2A14 "GLUT14, SLC2A3P3" ENSG00000173262 "Solute carrier family 2 member 14" Q8TDB8 12 7812512-7891148 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis, Sugar transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 81.3" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 65.7" "Cancer enriched" "Detected in single" 35 "testis cancer: 7.1" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 18.4;CACO-2: 31.0;SuSa: 35.5" HPA006539 Supported Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA006539: AB_1078984" "unprognostic (2.52e-1)" "unprognostic (4.74e-3)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (1.82e-3)" "unprognostic (8.62e-2)" "unprognostic (7.15e-2)" "unprognostic (1.89e-1)" "unprognostic (9.91e-3)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "unprognostic (8.46e-4)" "unprognostic (3.92e-2)" "unprognostic (3.41e-1)" "unprognostic (3.26e-2)" "unprognostic (1.22e-2)" 0.8 5.7 0.7 0.3 0.9 6.2 0.9 4.7 1.0 0.2 1.8 0.9 0.2 0.2 0.2 1.5 0.4 0.9 0.7 1.5 0.9 0.6 3.0 0.5 0.5 0.2 0.1 2.7 6.6 0.0 0.4 1.1 0.5 1.2 0.5 1.4 0.1 0.1 0.5 0.7 0.5 0.5 0.0 0.3 0.2 81.3 1.3 0.2 0.2 0.1 0.2 1.0 0.3 0.5 0.4 1.5 0.7 0.4 0.3 0.8 18.4 0.2 0.0 0.0 0.5 31.0 0.2 0.1 0.8 0.0 0.3 0.2 0.1 0.0 0.0 0.7 0.2 3.3 1.2 8.1 0.1 2.0 4.5 0.0 0.2 0.2 0.0 0.1 0.0 1.1 3.6 0.8 0.0 0.7 0.4 1.6 3.6 0.1 0.0 0.2 0.1 1.1 0.0 0.5 0.6 0.2 0.5 0.7 0.1 35.5 0.1 2.7 0.5 0.1 3.0 0.5 0.5 3.0 1.3 0.6 0.9 0.1 0.6 3.7 0.4 1.0 0.6 0.1 0.6 0.3 0.5 0.4 0.2 0.3 0.3 0.4 3.4 0.6 0.1 0.2 1.0 0.2 0.7 0.9 4.7 1.0 1.5 0.9 0.2 0.1 0.5 0.0 1.3 0.5 2.1 0.0 1.1 0.0 0.9 0.6 0.0 0.0 0.0 0.1 0.1 0.3 2.4 0.0 0.0 0.0 4.2 0.4 0.5 0.1 0.0 0.0 8.9 0.1 1.3 3.2 0.0 6.9 1.9 1.5 1.5 1.9 0.0 0.2 9.5 6.4 5.3 0.5 0.2 0.0 2.2 0.0 0.0 2.5 12.2 5.4 0.3 1.4 1.8 1.9 0.0 0.1 0.0 0.5 0.4 0.3 5.7 2.6 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.2 2.7 65.7 3.1 0.0 0.1 0.4 3.6 4.2 0.1 0.0 SLC2A4 GLUT4 ENSG00000181856 "Solute carrier family 2 member 4" P14672 17 7281718-7288257 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 98.8;skeletal muscle: 223.6" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 135.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "Hep G2: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" CAB016544 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB016544: AB_629533" "unprognostic (2.53e-1)" "unprognostic (7.40e-3)" "unprognostic (2.27e-1)" "unprognostic (8.12e-4)" "unprognostic (2.40e-1)" "unprognostic (6.28e-2)" "unprognostic (1.70e-2)" "unprognostic (1.66e-2)" "unprognostic (1.35e-1)" "unprognostic (3.83e-2)" "unprognostic (9.66e-2)" "unprognostic (2.24e-2)" "unprognostic (1.34e-3)" "unprognostic (4.23e-2)" "unprognostic (3.10e-1)" "unprognostic (2.30e-2)" "unprognostic (2.07e-2)" 16.9 5.2 1.4 0.2 1.7 1.1 11.2 0.9 1.5 9.2 0.9 53.1 0.8 9.3 1.2 5.9 11.3 0.7 98.8 1.3 1.1 2.6 3.7 2.1 0.2 1.0 1.5 3.2 0.8 3.4 4.4 0.6 1.2 9.9 1.1 0.4 6.3 3.3 223.6 4.1 9.7 4.3 1.0 0.3 11.7 3.3 1.3 0.1 4.5 63.2 0.0 27.0 5.6 1.1 0.0 0.0 0.4 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 1.7 0.9 1.5 1.3 1.1 1.0 1.5 1.2 1.0 1.3 1.1 1.7 0.0 0.0 1.0 0.0 1.8 0.9 0.3 2.2 0.1 1.5 1.3 135.2 0.0 0.2 0.0 0.0 0.3 0.0 1.0 7.9 0.1 16.6 0.2 0.1 3.7 0.0 10.7 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.3 1.8 2.8 0.1 0.0 0.0 0.8 0.0 0.3 0.3 4.8 0.0 0.1 7.2 1.0 0.0 6.0 0.0 0.0 0.0 0.1 1.2 8.6 0.0 0.8 0.8 0.3 0.4 0.4 32.9 7.0 19.8 1.7 2.2 0.5 1.1 1.0 0.1 0.5 1.0 0.7 SLC2A9 "Glut9, GLUTX, URATv1" ENSG00000109667 "Solute carrier family 2 member 9" Q9NRM0 4 9771153-10054936 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 29.3;liver: 21.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 27.4;Proximal tubular cells: 72.6" "Cancer enhanced" "Detected in many" "renal cancer: 6.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 36.9;myeloid DC: 30.5" "Group enriched" "Detected in many" 30 "dendritic cells: 30.5;monocytes: 36.9" "Cell line enhanced" "Detected in some" "HBEC3-KT: 48.1;Hep G2: 23.6;hTCEpi: 19.9;THP-1: 20.5;U-937: 13.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA066229, HPA075669" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA066229: AB_2685639, HPA075669: " "unprognostic (3.21e-1)" "unprognostic (8.99e-3)" "unprognostic (1.25e-2)" "unprognostic (2.01e-1)" "unprognostic (2.14e-2)" "unprognostic (2.56e-2)" "unprognostic (8.94e-2)" "unprognostic (6.94e-2)" "unprognostic (2.86e-2)" "unprognostic (1.28e-2)" "unprognostic (3.16e-1)" "unprognostic (2.23e-1)" "prognostic favorable (1.32e-11)" "unprognostic (1.01e-1)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.20e-1)" 1.6 2.6 1.0 2.0 1.2 2.1 4.2 1.3 1.2 2.5 2.7 1.8 10.7 1.4 2.4 5.2 3.5 2.4 2.3 1.1 1.6 29.3 21.4 4.2 2.0 2.3 1.5 1.6 1.0 2.4 1.4 7.6 2.0 3.5 1.6 1.2 16.6 18.8 0.5 2.2 8.4 2.0 1.8 1.8 1.0 0.7 2.0 4.2 2.7 0.5 1.4 6.4 4.0 3.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.1 0.0 0.3 2.4 0.0 3.5 0.7 0.0 7.3 0.0 48.1 0.0 8.2 0.3 0.0 0.0 23.6 1.6 0.1 6.3 3.4 19.9 0.0 4.8 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.3 2.4 0.0 0.4 0.1 1.5 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.5 0.1 0.0 36.9 0.9 0.3 7.6 0.3 0.3 0.3 0.1 30.5 0.1 0.2 0.1 1.1 0.2 0.9 12.2 0.2 9.1 1.0 1.2 1.3 1.2 1.1 1.6 2.3 1.5 2.0 1.8 2.0 3.0 1.4 0.0 0.0 8.1 1.3 0.9 13.4 27.4 6.2 0.0 4.6 6.1 2.4 0.0 5.7 3.7 2.1 18.7 0.5 1.7 3.9 0.5 5.1 4.1 2.1 1.5 0.0 1.3 4.4 1.1 1.8 1.6 1.1 11.5 1.3 0.5 2.2 5.2 10.3 0.0 5.6 0.9 10.2 8.7 3.7 3.4 0.0 8.8 0.0 15.9 4.4 1.2 1.0 10.6 1.1 0.6 0.5 0.4 0.3 2.0 8.1 72.6 3.0 0.4 0.0 4.6 1.6 1.1 1.9 5.4 0.6 8.5 0.9 0.7 2.5 7.7 SLC30A10 "DKFZp547M236, ZnT-10, ZNT8, ZRC1" ENSG00000196660 "Solute carrier family 30 member 10" Q6XR72 1 219685427-219958647 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 23.9;liver: 33.5" "Cell type enhanced" "Detected in some" "Astrocytes: 20.2;Distal enterocytes: 44.3;Early spermatids: 38.3;Hepatocytes: 21.1;Late spermatids: 36.1;Paneth cells: 14.4;Proximal enterocytes: 13.6" "Cancer enriched" "Detected in some" 14 "liver cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.0;HEL: 1.5;K-562: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064547 Enhanced NA NA "Cluster 42: Non-specific - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA064547: AB_2732715" "unprognostic (7.88e-2)" "unprognostic (1.07e-2)" "unprognostic (1.02e-1)" "unprognostic (7.25e-2)" "unprognostic (1.75e-2)" "unprognostic (3.74e-3)" "unprognostic (6.96e-2)" "unprognostic (3.72e-2)" "unprognostic (1.41e-1)" "unprognostic (1.95e-2)" "unprognostic (5.10e-2)" "unprognostic (3.10e-3)" "unprognostic (4.47e-7)" "unprognostic (3.16e-1)" "unprognostic (6.11e-2)" "unprognostic (6.19e-3)" "unprognostic (5.72e-2)" 0.0 0.0 6.0 0.0 6.1 0.3 0.0 4.4 7.6 0.0 7.4 3.8 23.9 0.0 0.0 0.0 0.0 0.4 0.0 5.9 5.7 0.0 33.5 0.0 0.0 5.4 5.9 0.2 0.0 0.0 0.0 0.0 5.6 0.1 5.0 0.4 0.0 0.0 0.7 0.1 8.9 0.0 4.5 0.0 0.0 0.7 6.5 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.2 0.2 0.2 0.3 0.3 0.3 0.2 0.1 0.1 6.0 6.1 4.4 7.6 5.9 5.7 5.4 5.9 5.6 4.5 6.5 4.7 0.0 0.0 0.0 20.2 0.2 0.3 0.0 0.2 0.0 0.3 0.2 0.0 1.2 1.5 0.1 0.0 0.0 0.1 0.0 44.3 0.0 0.2 38.3 0.0 0.0 1.0 0.0 2.7 4.3 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.4 21.1 0.1 0.0 4.3 0.6 0.0 0.6 0.3 36.1 1.2 0.0 1.8 9.4 0.0 3.1 0.0 3.0 3.3 0.0 14.4 1.5 0.0 0.0 13.6 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.9 0.0 0.1 0.3 0.0 1.3 0.8 0.0 SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 753.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 477.5;Alveolar cells type 2: 1315.9;Club cells: 179.9;Glandular and luminal cells: 241.3;Respiratory ciliated cells: 217.0" "Group enriched" "Detected in many" 4 "lung cancer: 252.6;ovarian cancer: 191.7;thyroid cancer: 585.2" "Region enriched" "Detected in single" 6 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 82 "BEWO: 32.2;EFO-21: 121.0;RPTEC TERT1: 86.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Lung - Lung function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: AB_10670536, HPA066474: " "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (7.33e-2)" "unprognostic (9.83e-2)" "unprognostic (2.37e-2)" "unprognostic (6.60e-3)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" 0.4 0.8 0.0 0.3 0.0 0.0 19.1 2.1 0.2 66.6 6.9 0.1 16.4 34.6 0.1 1.5 69.8 9.0 0.2 0.1 0.0 16.7 1.2 753.0 0.1 0.0 0.0 1.3 7.3 0.0 2.1 4.8 0.1 1.0 0.0 0.5 90.2 16.8 0.1 2.6 4.3 0.2 0.0 0.7 2.5 2.7 0.3 2.1 33.6 0.0 7.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 32.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 121.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.1 0.0 0.2 0.1 0.1 86.8 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 477.5 1315.9 0.0 0.1 0.0 0.1 79.1 0.0 0.0 41.5 7.5 0.8 34.3 179.9 20.2 0.0 1.4 0.0 0.0 5.9 72.2 5.4 78.6 30.3 2.5 0.0 0.0 0.1 8.5 0.0 2.6 0.0 241.3 29.0 0.0 0.0 0.0 0.2 0.0 0.1 1.2 26.4 0.0 0.0 20.8 1.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 2.5 0.0 0.0 11.8 13.6 3.4 217.0 0.0 0.0 0.0 5.8 2.1 0.1 0.0 0.0 0.3 4.8 0.0 1.8 4.0 SLC35D2 "SQV7L, UGTrel8" ENSG00000130958 "Solute carrier family 35 member D2" Q76EJ3 9 96313444-96383711 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 117.2;Proximal enterocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 103.8;Hep G2: 132.3" HPA064047 Approved Supported "Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "HPA064047: AB_2685182" "unprognostic (3.67e-1)" "unprognostic (5.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.16e-2)" "unprognostic (3.17e-1)" "unprognostic (8.86e-3)" "unprognostic (4.25e-3)" "unprognostic (2.24e-2)" "unprognostic (4.12e-1)" "unprognostic (5.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-2)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (1.44e-1)" 14.7 8.8 13.5 14.4 20.6 11.4 16.4 17.8 20.6 16.5 12.3 49.1 65.1 14.9 12.1 13.7 14.6 20.6 12.2 14.3 16.0 32.1 56.4 19.2 12.4 25.5 19.7 17.3 31.4 16.4 7.2 25.5 22.1 14.2 46.4 4.3 13.0 11.0 3.9 9.4 65.8 13.9 16.6 10.0 43.1 7.2 20.1 7.5 29.5 6.9 11.7 17.2 13.1 27.8 33.2 27.6 15.8 30.2 20.3 37.3 27.9 14.7 30.2 21.6 17.5 60.4 103.8 0.6 24.5 13.5 49.9 47.6 22.2 21.8 18.7 16.4 16.8 11.3 9.8 132.3 32.5 0.1 0.0 32.2 27.6 16.3 48.7 51.0 46.7 0.0 22.3 0.4 23.7 27.2 0.3 0.1 13.2 67.5 28.5 0.1 0.0 0.0 54.4 21.3 5.5 35.9 11.9 24.8 68.5 53.3 16.4 24.7 41.3 14.5 16.2 21.2 13.8 0.0 0.9 0.1 30.2 0.1 20.4 1.2 0.9 0.6 1.3 1.1 1.6 0.7 2.1 2.9 1.2 0.9 0.7 1.4 0.1 1.8 2.1 0.2 3.9 0.5 13.5 20.6 17.8 20.6 14.3 16.0 25.5 19.7 22.1 16.6 20.1 27.8 14.5 9.6 11.0 12.1 4.3 5.2 8.9 2.1 1.8 1.1 15.1 13.1 7.2 27.1 4.6 12.9 2.1 28.1 12.9 61.7 11.7 8.1 0.2 21.0 14.0 12.6 9.6 1.3 0.8 24.5 45.1 9.5 20.4 31.6 4.5 20.0 13.2 43.2 20.5 1.7 1.1 42.0 4.1 23.0 9.7 0.6 10.8 17.7 17.8 20.6 8.9 10.2 7.2 11.1 117.2 25.4 43.5 6.0 6.3 15.5 67.0 23.6 6.7 3.6 13.1 6.8 11.2 1.4 4.4 8.6 5.4 26.5 14.6 7.0 34.9 17.9 SLC35F2 FLJ13018 ENSG00000110660 "Solute carrier family 35 member F2" Q8IXU6 11 107790991-107928293 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 37.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.0;Basal prostatic cells: 34.5;Suprabasal keratinocytes: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 188.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048185, HPA060150" Enhanced Approved "Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA048185: AB_2680304, HPA060150: " "unprognostic (7.73e-2)" "unprognostic (3.28e-3)" "unprognostic (8.37e-3)" "unprognostic (5.77e-2)" "unprognostic (1.38e-3)" "unprognostic (3.07e-2)" "unprognostic (7.26e-2)" "prognostic unfavorable (4.03e-4)" "unprognostic (6.22e-2)" "unprognostic (8.20e-2)" "prognostic unfavorable (5.92e-6)" "unprognostic (1.24e-1)" "unprognostic (4.10e-2)" "unprognostic (1.34e-1)" "unprognostic (7.33e-2)" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" 4.1 1.2 3.3 7.2 3.9 5.1 5.5 2.3 3.6 16.3 3.2 17.9 19.0 6.3 11.6 12.2 13.5 5.1 3.5 3.8 4.2 10.0 0.5 5.7 7.9 3.5 3.4 5.0 5.4 6.0 3.4 3.2 3.3 22.3 20.4 12.7 37.4 6.1 1.1 20.5 17.8 4.6 4.3 4.0 7.0 4.5 3.5 5.5 7.2 1.5 13.9 7.9 9.5 3.6 30.8 19.8 2.3 30.1 15.2 22.6 29.0 6.8 3.9 17.3 22.7 84.2 31.4 51.2 67.7 20.1 94.1 63.1 37.3 60.5 34.2 40.3 34.8 28.5 18.1 34.1 24.8 65.0 14.2 15.7 36.9 58.3 123.1 53.2 91.7 38.3 74.0 20.7 13.0 17.0 28.3 69.7 20.5 67.5 188.4 57.7 23.9 68.9 100.1 26.7 46.6 20.1 21.9 54.8 14.8 24.7 38.1 15.2 68.0 33.4 53.9 0.8 73.5 54.6 62.5 53.9 21.4 22.0 22.4 0.3 0.2 0.0 3.1 0.1 8.2 10.6 5.3 5.4 6.9 6.5 1.9 2.7 0.6 3.7 0.0 0.3 13.5 1.8 3.3 3.9 2.3 3.6 3.8 4.2 3.5 3.4 3.3 4.3 3.5 3.6 2.7 9.6 1.5 2.0 10.3 46.0 34.5 6.4 14.8 1.1 3.7 2.3 0.6 7.2 9.6 3.7 12.5 0.9 2.5 21.5 3.9 9.5 0.3 13.6 2.8 13.7 6.0 1.7 3.9 8.2 19.1 8.3 6.1 22.9 2.5 5.0 0.7 0.0 4.8 0.0 4.4 10.1 4.1 0.3 15.0 1.0 0.9 3.6 23.2 6.5 3.7 1.2 1.0 4.0 0.4 25.9 10.0 2.6 23.6 20.6 15.1 6.4 0.1 8.0 6.6 2.8 3.1 0.3 7.5 8.6 50.3 4.5 5.7 4.9 24.7 16.6 SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 129.9;Karpas-707: 117.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Cytosol" "HPA034655: AB_10696359" "unprognostic (2.26e-1)" "unprognostic (7.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.11e-4)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" 18.6 20.7 9.6 7.3 10.5 4.6 16.2 10.1 9.2 14.5 8.4 10.1 7.9 11.9 7.3 22.0 10.7 7.3 13.8 9.6 11.8 19.5 17.7 11.9 6.5 13.9 12.9 8.5 10.3 21.3 10.8 9.4 12.3 11.4 5.7 5.8 14.5 8.1 12.8 21.2 10.0 10.1 10.4 10.8 11.3 5.1 13.0 5.7 16.0 9.9 7.6 12.1 13.0 11.6 24.6 43.6 12.3 32.6 41.7 19.4 20.4 14.9 20.3 16.8 15.2 27.9 44.5 6.6 23.4 18.7 42.0 29.4 18.1 26.9 11.8 11.5 10.1 7.6 16.4 23.3 129.9 7.8 36.4 29.8 26.9 18.9 62.7 7.6 19.9 9.6 14.2 117.3 16.9 40.5 10.0 7.0 7.6 17.2 10.9 8.9 35.9 10.9 44.1 20.3 9.6 12.7 22.8 37.4 25.4 10.1 14.1 8.2 19.2 21.8 24.0 30.7 15.2 23.9 32.6 12.9 23.6 13.4 21.0 12.1 18.1 8.0 11.9 25.6 7.0 4.8 8.2 10.8 11.4 3.6 5.3 7.9 11.7 13.6 30.9 7.8 5.9 9.5 9.6 10.5 10.1 9.2 9.6 11.8 13.9 12.9 12.3 10.4 13.0 11.6 39.0 12.8 10.5 11.8 5.9 17.0 13.2 10.2 7.4 17.2 17.5 10.2 13.5 28.6 11.1 33.1 6.2 24.1 12.0 21.5 7.9 34.2 1.7 13.4 29.7 20.8 9.1 0.8 6.9 38.7 22.3 25.2 12.2 22.8 1.3 11.9 31.8 25.4 51.2 15.2 7.9 11.2 8.2 61.0 16.8 1.5 18.3 28.8 28.4 4.7 19.8 19.2 11.3 9.0 10.8 48.2 14.3 12.0 5.5 18.3 21.5 57.2 9.0 11.1 26.3 17.8 20.2 3.7 7.1 14.9 25.7 38.0 10.6 16.8 11.2 11.7 SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Early spermatids: 65.4;Inhibitory neurons: 42.4;Spermatocytes: 35.5" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 73.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" 14.9 15.4 20.9 2.1 21.2 0.5 11.1 23.1 26.4 5.1 16.5 3.8 1.0 4.3 4.6 2.6 5.7 5.3 8.1 20.0 24.4 3.9 4.4 7.0 1.9 21.4 25.0 5.5 7.6 6.7 19.3 7.4 26.9 4.1 2.0 5.3 3.1 2.6 2.4 3.7 2.9 5.1 22.1 3.2 2.9 14.4 22.6 2.8 8.5 5.4 1.2 6.5 5.0 21.0 3.9 10.7 10.6 4.8 20.8 17.1 0.0 16.9 73.1 24.7 37.0 10.1 5.7 0.0 12.7 17.5 39.3 1.3 12.7 0.7 22.8 0.1 3.5 3.2 12.0 6.3 26.6 0.1 0.0 24.2 1.8 21.5 5.9 18.0 18.8 6.8 1.8 0.1 32.1 0.0 4.7 3.3 2.3 0.0 7.9 4.2 7.1 0.2 21.1 0.9 17.5 11.7 13.7 0.0 24.0 3.6 0.0 1.8 13.1 18.4 4.7 8.2 18.6 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 20.9 21.2 23.1 26.4 20.0 24.4 21.4 25.0 26.9 22.1 22.6 21.0 22.4 12.8 7.0 54.2 2.5 3.3 4.9 12.0 7.4 4.7 0.7 0.8 2.5 1.5 7.1 1.8 12.5 1.3 2.7 0.8 1.9 3.3 65.4 1.0 1.6 30.6 4.2 4.4 34.0 10.7 1.3 12.4 0.5 1.3 2.5 3.6 27.8 2.3 0.7 6.7 42.4 1.0 0.0 2.2 7.3 30.3 9.9 2.1 3.6 17.8 3.7 7.8 15.5 15.6 6.1 10.0 0.1 3.0 3.7 4.7 0.6 0.7 1.4 4.6 6.6 4.7 4.8 35.5 16.1 1.2 3.0 2.2 3.8 3.1 0.6 2.0 SLC37A2 FLJ00171 ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 78.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.4;Hofbauer cells: 36.5;Kupffer cells: 22.0;Macrophages: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.2" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.2" "Cell line enhanced" "Detected in many" "A-431: 33.8;CAPAN-2: 70.3;hTCEpi: 34.9;hTERT-HME1: 64.8;U-138 MG: 47.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" 4.2 24.2 1.7 16.9 2.6 1.4 4.6 2.4 3.7 2.3 2.1 8.0 9.1 1.0 1.3 13.4 1.2 5.1 1.5 1.9 2.3 0.7 5.9 5.9 5.7 4.3 2.7 1.0 1.2 1.1 0.2 7.4 3.8 2.6 10.2 0.5 78.8 1.4 0.6 20.9 7.7 3.1 3.2 15.8 2.1 1.6 5.2 2.1 0.6 0.9 5.1 11.9 7.7 7.3 33.8 0.1 1.0 0.4 0.6 0.8 0.6 1.6 2.8 1.0 2.5 0.2 70.3 0.4 9.4 0.4 2.5 21.0 0.4 20.9 3.8 0.9 0.6 6.6 1.6 2.4 0.1 0.3 0.9 0.7 34.9 2.6 64.8 2.7 1.7 1.3 0.5 2.2 3.1 0.3 0.3 4.6 1.9 0.2 1.0 0.4 2.7 0.8 1.0 17.6 0.3 0.3 4.8 2.9 2.6 0.5 0.3 1.8 3.7 47.2 1.9 0.7 1.6 1.8 1.5 1.1 1.7 2.4 4.1 0.2 12.3 0.0 0.0 14.1 0.0 0.4 0.0 0.1 5.5 0.1 0.1 0.1 1.3 0.0 19.2 0.2 0.0 5.4 1.7 2.6 2.4 3.7 1.9 2.3 4.3 2.7 3.8 3.2 5.2 7.3 0.7 0.0 0.6 0.3 3.8 0.3 1.4 0.5 1.2 1.5 1.4 1.1 1.1 1.5 1.6 0.0 2.1 0.6 0.7 13.4 0.0 0.1 1.6 1.9 1.4 1.3 0.0 2.7 0.3 0.0 0.8 0.5 0.0 4.9 2.5 0.4 1.8 0.3 36.5 0.0 0.3 0.1 0.0 22.0 1.4 2.2 0.9 22.7 0.0 8.4 7.3 0.3 3.1 1.0 0.2 0.1 3.3 1.2 1.7 1.0 0.0 0.1 0.2 0.8 0.0 0.8 0.6 2.7 1.1 5.7 0.9 3.4 1.2 0.4 0.1 3.2 SLC39A2 ZIP2 ENSG00000165794 "Solute carrier family 39 member 2" Q9NP94 14 20999255-21001871 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;seminal vesicle: 33.2;skin 1: 37.5" "Cell type enhanced" "Detected in some" "Muller glia cells: 22.3;Squamous epithelial cells: 12.0;Suprabasal keratinocytes: 6.0;Urothelial cells: 4.4" "Group enriched" "Detected in many" 4 "cervical cancer: 5.1;colorectal cancer: 3.3;head and neck cancer: 6.1;melanoma: 1.9;urothelial cancer: 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 71 "HaCaT: 23.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA030489, HPA073231" Uncertain Approved "Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "Cytoplasmic bodies" "HPA030489: AB_10601488, HPA073231: " "unprognostic (2.76e-2)" "unprognostic (4.86e-2)" "unprognostic (9.72e-2)" "unprognostic (2.37e-1)" "unprognostic (2.46e-1)" "unprognostic (2.71e-1)" "unprognostic (3.42e-1)" "unprognostic (1.70e-1)" "unprognostic (4.43e-1)" "unprognostic (6.20e-3)" "unprognostic (3.31e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-2)" "unprognostic (1.91e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-1)" "unprognostic (2.30e-3)" 0.1 0.0 0.2 0.1 0.2 0.0 1.9 0.3 0.3 8.0 0.2 1.9 0.0 0.3 0.1 18.8 0.5 0.4 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.0 2.3 0.1 0.3 0.2 12.2 1.3 3.7 4.1 33.2 0.2 37.5 0.1 0.2 0.3 0.0 0.0 0.1 0.3 2.8 0.0 0.0 2.7 0.3 14.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 23.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 0.0 0.2 0.8 0.3 0.4 0.0 0.7 0.0 2.1 0.1 0.0 0.5 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 22.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.8 0.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 12.0 6.0 0.3 0.0 0.0 1.4 4.4 SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 132.0;prostate: 83.0;stomach 1: 83.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 546.0;Exocrine glandular cells: 213.4;Intestinal goblet cells: 327.8;Paneth cells: 299.3;Proximal enterocytes: 267.7;Respiratory ciliated cells: 406.7;Undifferentiated cells: 259.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" 0.8 8.2 0.0 2.5 0.0 1.0 5.3 0.0 0.0 22.4 0.0 132.0 100.8 5.9 2.5 2.0 46.9 18.8 0.0 0.0 0.0 32.1 0.4 14.9 0.1 0.3 0.1 1.6 8.9 0.0 16.1 3.5 0.1 83.0 30.3 0.0 42.6 3.9 0.0 1.1 86.8 2.9 0.0 1.6 83.4 0.7 0.0 0.2 1.9 0.0 0.7 11.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 3.7 22.4 36.0 0.0 3.8 0.5 23.0 71.4 0.6 0.3 14.6 6.1 0.4 38.6 180.2 66.2 0.0 0.3 0.5 546.0 3.9 111.2 2.3 127.4 8.9 6.2 46.7 0.0 0.1 213.4 0.5 2.4 208.5 67.5 2.5 1.1 0.4 0.0 0.5 0.0 0.1 327.8 91.6 0.0 0.0 3.2 1.5 2.5 0.0 0.0 1.6 0.7 0.0 0.0 0.0 184.0 299.3 0.4 0.3 142.0 267.7 61.5 406.7 0.6 0.0 0.8 11.9 0.2 0.2 0.5 0.4 0.7 2.3 5.5 259.6 139.4 SLC45A2 "AIM-1, MATP, OCA4" ENSG00000164175 "Solute carrier family 45 member 2" Q9UMX9 5 33944623-33984693 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Sensory transduction, Vision" "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 1.2;skin 1: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Early spermatids: 3.1;Excitatory neurons: 4.1;Inhibitory neurons: 5.4;Late spermatids: 5.1;Melanocytes: 12.4;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 4.7" "Cancer enriched" "Detected in some" 18 "melanoma: 47.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 28 "SK-MEL-30: 60.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.97e-1)" "unprognostic (3.99e-2)" "unprognostic (3.55e-1)" "unprognostic (2.39e-2)" "unprognostic (2.36e-2)" "unprognostic (1.09e-1)" "unprognostic (8.45e-2)" "unprognostic (5.34e-3)" "unprognostic (4.06e-2)" "unprognostic (8.45e-2)" "unprognostic (7.39e-4)" "unprognostic (1.40e-2)" "unprognostic (1.84e-3)" "unprognostic (1.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.48e-2)" "unprognostic (3.39e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.4 1.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.1 0.0 0.2 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 60.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.3 0.1 0.1 0.2 0.1 0.2 0.4 0.1 0.0 0.0 1.0 0.0 0.6 0.1 0.0 0.0 0.6 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.1 0.3 0.1 0.3 0.0 0.0 4.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.4 5.1 0.0 0.0 12.4 0.0 0.0 0.1 0.0 2.5 4.7 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.1 0.1 0.0 SLC46A2 "Ly110, TSCOT" ENSG00000119457 "Solute carrier family 46 member 2" Q9BY10 9 112878920-112890876 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 16.5;lung: 10.4;lymphoid tissue: 16.0;skin 1: 24.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 39.8;Endometrial ciliated cells: 15.8;Glandular and luminal cells: 6.9;Kupffer cells: 11.8;monocytes: 12.4" "Cancer enhanced" "Detected in some" "lung cancer: 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 24.6;intermediate monocyte: 12.1" "Lineage enriched" "Detected in many" 5 "monocytes: 24.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020098 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 11: Alveolar cells - Smell perception" "HPA020098: AB_2670363" "unprognostic (1.26e-1)" "unprognostic (5.15e-3)" "unprognostic (1.10e-2)" "unprognostic (1.53e-3)" "unprognostic (3.57e-3)" "unprognostic (2.10e-2)" "unprognostic (4.56e-1)" "unprognostic (2.18e-1)" "unprognostic (8.10e-2)" "unprognostic (1.50e-3)" "unprognostic (3.50e-1)" "unprognostic (1.38e-1)" "unprognostic (1.77e-2)" "unprognostic (2.37e-1)" "unprognostic (2.71e-2)" "unprognostic (1.83e-1)" "unprognostic (7.82e-2)" 0.1 0.0 0.1 0.6 0.1 0.1 0.9 0.5 0.2 16.5 0.0 0.0 0.0 3.0 4.7 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 10.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 1.5 0.0 24.1 0.0 0.4 0.0 0.9 0.0 0.6 0.5 16.0 0.0 0.0 0.1 3.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.1 12.1 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.0 10.1 0.2 0.0 6.6 0.1 0.1 0.5 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.5 0.3 0.0 0.0 39.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.7 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 15.8 0.8 0.3 0.0 0.0 0.9 0.0 0.0 0.2 0.0 6.9 0.0 0.0 0.4 0.1 2.1 0.0 0.4 0.0 0.0 11.8 1.8 4.4 0.0 4.1 0.0 0.0 12.4 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 SLC46A3 "DKFZp686A1775, FLJ42613" ENSG00000139508 "Solute carrier family 46 member 3" Q7Z3Q1 13 28700064-28718970 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 76.0;liver: 96.0" "Cell type enhanced" "Detected in many" "Granulosa cells: 53.2;Hepatocytes: 51.3;Proximal enterocytes: 125.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.0;T-47d: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039930 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Actin filaments" "HPA039930: AB_10673263" "unprognostic (5.16e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" "unprognostic (3.88e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "prognostic favorable (7.09e-4)" "unprognostic (3.13e-1)" "unprognostic (3.33e-1)" "unprognostic (1.26e-1)" "unprognostic (5.69e-2)" "unprognostic (7.35e-2)" "unprognostic (1.14e-1)" "unprognostic (5.60e-2)" "unprognostic (9.14e-3)" "unprognostic (6.47e-3)" 13.8 11.7 5.1 10.2 5.7 2.9 10.0 7.7 5.2 14.7 10.0 19.8 46.7 5.6 11.1 4.0 7.5 23.8 12.3 4.7 5.7 18.2 96.0 11.5 16.3 5.9 6.0 3.9 6.7 23.9 10.2 9.5 6.1 6.5 18.8 15.9 9.0 9.9 8.5 4.2 76.0 8.2 6.6 18.2 7.8 11.0 6.6 11.6 12.5 8.6 11.1 7.0 2.2 5.6 0.0 2.8 0.0 7.6 6.0 2.3 0.2 2.7 15.7 3.0 4.4 0.1 6.6 5.2 4.7 4.0 11.5 0.6 3.5 1.4 4.5 3.9 6.2 3.6 0.0 0.0 11.4 0.0 4.3 9.8 2.9 4.5 7.3 3.0 5.6 15.7 3.9 0.0 14.5 3.0 8.6 0.6 0.3 8.0 2.2 3.5 13.3 0.2 27.0 0.9 1.2 0.4 0.0 14.1 5.7 3.1 20.6 4.6 2.0 1.4 2.7 0.4 16.0 4.0 2.0 0.8 0.9 0.0 2.8 33.1 8.9 3.8 10.3 13.1 8.6 7.4 8.0 10.1 11.7 9.7 11.4 10.8 9.8 7.0 19.4 11.0 10.6 8.7 5.1 5.7 7.7 5.2 4.7 5.7 5.9 6.0 6.1 6.6 6.6 5.6 6.2 0.0 5.4 16.0 14.5 1.9 0.1 7.4 1.8 33.7 15.1 3.3 9.6 17.2 15.6 9.2 8.4 0.6 16.4 49.0 1.9 15.5 4.6 2.1 1.7 12.2 3.6 4.6 11.6 5.6 0.3 6.2 0.0 2.1 25.9 53.2 17.5 51.3 10.8 21.9 13.0 6.8 2.0 32.1 36.6 1.8 1.5 22.5 7.2 16.9 9.3 14.2 12.3 14.6 15.6 3.5 5.3 2.2 6.5 0.6 125.0 10.1 15.4 9.8 0.0 2.8 7.2 2.6 0.9 4.9 1.7 0.7 11.4 16.8 13.9 0.2 SLC47A1 "FLJ10847, MATE1" ENSG00000142494 "Solute carrier family 47 member 1" Q96FL8 17 19495385-19579034 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 127.3;kidney: 100.3;liver: 103.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 189.2;Hepatocytes: 43.3;Proximal tubular cells: 52.9;Skeletal myocytes: 67.8" "Cancer enhanced" "Detected in many" "renal cancer: 37.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 12.2;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 6 "dendritic cells: 6.6;granulocytes: 12.2" "Cell line enhanced" "Detected in many" "A549: 21.3;AN3-CA: 16.7;Hep G2: 41.5;U-266/70: 31.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021987 Enhanced NA NA 18000 "Cluster 49: Eosinophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "HPA021987: AB_1857185" "unprognostic (1.17e-2)" "unprognostic (1.94e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.54e-8)" "unprognostic (7.87e-2)" "unprognostic (8.34e-2)" "unprognostic (2.92e-2)" "prognostic favorable (1.88e-5)" "unprognostic (4.84e-2)" "unprognostic (6.89e-2)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.06e-5)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.91e-2)" "unprognostic (9.40e-2)" 1.9 127.3 2.1 0.8 2.6 2.7 1.3 3.5 15.8 29.4 9.3 2.0 1.3 16.2 2.5 1.9 7.4 3.8 5.4 15.7 1.6 100.3 103.9 7.0 1.6 3.0 2.5 7.7 0.3 1.4 16.5 0.4 3.1 6.3 1.0 1.2 2.6 12.3 34.1 25.0 1.3 7.7 2.5 3.7 1.2 14.5 4.3 1.5 6.2 37.7 1.3 1.0 10.6 3.3 0.1 21.3 0.6 16.7 0.5 0.1 0.1 0.6 0.5 2.5 2.3 0.0 0.6 0.2 3.9 3.1 8.3 0.1 7.4 0.6 0.6 0.1 9.8 0.2 10.6 41.5 0.2 0.2 0.5 0.4 3.7 1.9 0.3 2.8 5.9 0.0 0.0 0.0 0.0 3.0 0.1 0.4 2.2 0.3 0.8 0.2 0.2 0.2 0.0 1.3 3.9 3.4 7.0 0.1 1.9 5.6 7.1 1.9 0.0 0.1 0.8 0.3 2.0 31.0 13.1 0.1 0.8 0.1 3.6 0.3 1.4 12.2 0.3 0.9 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.6 0.2 0.0 0.1 6.6 0.0 0.5 2.1 2.6 3.5 15.8 15.7 1.6 3.0 2.5 3.1 2.5 4.3 3.3 0.5 6.4 3.7 0.7 1.3 4.7 2.3 0.4 6.2 0.9 0.1 0.8 4.1 4.3 0.1 1.8 0.0 0.0 1.7 0.0 3.9 0.1 15.5 3.0 1.3 1.2 0.0 0.0 3.5 0.0 0.0 4.4 0.0 9.2 5.7 189.2 0.0 43.3 1.5 0.0 14.4 0.0 0.0 2.9 1.2 4.8 3.7 2.5 1.8 3.7 0.4 1.4 0.0 2.5 0.3 0.0 0.0 1.5 3.9 2.3 0.0 52.9 0.8 0.9 6.6 67.8 3.3 0.6 1.1 1.1 6.7 0.0 1.7 0.3 0.0 1.5 SLC49A3 "FLJ22269, LP2561, MFSD7" ENSG00000169026 "Solute carrier family 49 member 3" Q6UXD7 4 681829-689271 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 12.8;Breast glandular cells: 14.6;Collecting duct cells: 14.7;Ductal cells: 19.2;Extravillous trophoblasts: 33.9;Hofbauer cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 8.7;CAPAN-2: 5.8;SK-BR-3: 8.2;T-47d: 25.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043593 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" "HPA043593: AB_10959611" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (8.77e-2)" "unprognostic (4.70e-2)" "unprognostic (9.40e-2)" "unprognostic (1.84e-3)" "unprognostic (2.22e-1)" "unprognostic (1.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.56e-1)" "unprognostic (9.22e-2)" "unprognostic (2.08e-1)" "prognostic favorable (2.66e-5)" "unprognostic (8.35e-2)" "unprognostic (4.92e-2)" "unprognostic (7.48e-2)" "unprognostic (1.11e-1)" 8.2 3.2 2.4 4.4 2.1 3.5 9.0 2.7 3.0 4.5 3.5 4.2 5.9 3.4 4.2 4.4 3.3 3.7 8.3 1.7 2.3 8.3 5.8 8.1 3.0 3.2 2.2 1.2 4.8 4.6 1.9 2.7 3.0 5.0 2.3 12.6 8.4 2.1 3.0 10.2 5.9 2.1 2.7 8.5 8.4 8.9 3.5 0.6 8.5 1.9 1.7 4.3 4.9 2.9 0.1 0.1 2.7 1.9 1.9 3.7 8.7 1.0 0.0 0.7 0.6 0.4 5.8 0.1 0.2 4.5 0.4 0.2 0.0 0.0 0.2 0.6 0.6 1.6 0.7 0.2 0.8 0.0 1.2 2.5 0.0 3.4 0.0 0.0 1.3 0.3 0.4 0.5 0.0 0.1 0.1 0.7 0.3 0.4 0.5 0.0 0.3 0.6 0.0 0.3 0.9 0.7 0.0 8.2 0.5 0.5 25.8 1.6 0.3 0.8 0.3 0.4 0.3 2.8 1.6 0.1 0.3 0.7 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.4 0.2 0.0 0.1 0.3 2.4 2.1 2.7 3.0 1.7 2.3 3.2 2.2 3.0 2.7 3.5 2.9 12.8 3.2 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.6 8.4 0.0 0.0 1.8 14.7 0.0 0.7 3.1 0.0 1.9 19.2 0.0 2.1 6.0 4.3 0.0 0.0 0.0 0.4 33.9 4.3 0.0 4.1 0.0 0.8 0.0 0.0 35.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 3.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.8 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 4.9 0.7 0.5 0.0 0.0 SLC4A11 "BTR1, CDPD1, CHED2, dJ794I6.2, FECD4, NaBC1" ENSG00000088836 "Solute carrier family 4 member 11" Q8NBS3 20 3227417-3239559 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Symport, Transport" "Corneal dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 51.3;salivary gland: 54.0;thyroid gland: 60.9" "Cell type enhanced" "Detected in many" "Club cells: 25.5;Collecting duct cells: 112.2;Ionocytes: 79.3;Respiratory ciliated cells: 48.1;Sertoli cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 70.6;Hep G2: 43.0;RT4: 30.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018120, HPA058377" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Vesicles "HPA018120: AB_1857186, HPA058377: " "unprognostic (2.33e-1)" "prognostic favorable (9.03e-4)" "unprognostic (1.18e-2)" "unprognostic (3.05e-2)" "unprognostic (1.00e-1)" "unprognostic (6.52e-2)" "unprognostic (9.66e-3)" "unprognostic (3.73e-2)" "unprognostic (3.10e-3)" "unprognostic (1.52e-3)" "unprognostic (2.94e-1)" "unprognostic (2.64e-1)" "prognostic favorable (6.21e-6)" "unprognostic (7.37e-2)" "unprognostic (4.30e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-3)" 2.4 6.9 4.5 0.7 3.5 0.4 3.4 2.3 3.1 10.9 5.6 0.4 0.1 0.5 2.6 16.5 1.7 1.1 0.8 2.9 1.4 51.3 0.2 2.0 1.4 2.0 2.3 0.2 0.5 0.6 4.3 0.2 2.6 5.4 0.3 0.4 54.0 7.0 5.2 12.8 0.6 0.3 0.8 0.7 2.5 5.9 4.3 1.0 60.9 0.1 1.8 3.4 5.8 1.9 11.0 15.5 1.8 7.9 5.1 1.3 21.1 5.4 3.4 2.8 1.6 1.1 14.1 0.0 6.1 1.9 6.6 70.6 8.3 16.8 0.5 0.1 3.2 0.7 7.5 43.0 3.2 4.0 13.6 0.7 6.8 3.4 3.2 2.3 7.0 9.8 1.6 9.7 2.9 7.2 0.5 0.4 12.1 13.6 20.7 2.6 10.3 3.5 16.9 30.7 0.9 4.9 2.7 17.5 0.3 5.4 6.7 7.0 12.1 2.1 7.0 0.5 2.7 0.4 0.6 0.1 0.1 2.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 4.5 3.5 2.3 3.1 2.9 1.4 2.0 2.3 2.6 0.8 4.3 1.9 0.8 0.0 0.0 1.6 0.0 0.8 2.2 16.3 8.0 0.2 4.9 4.4 1.1 0.0 25.5 112.2 0.0 0.1 0.6 0.8 0.0 0.7 5.8 2.3 0.6 0.7 0.0 0.0 0.3 0.5 0.1 0.3 5.1 4.2 0.0 0.2 1.1 0.0 0.4 0.0 0.1 0.2 79.3 0.3 0.0 2.2 0.0 0.5 0.0 0.0 0.6 0.1 0.0 0.0 0.3 3.0 1.3 0.4 0.0 3.7 0.0 0.5 48.1 0.2 26.3 0.6 5.8 3.0 4.7 3.3 0.4 0.0 0.2 0.1 0.2 5.7 SLC4A3 "AE3, SLC2C" ENSG00000114923 "Solute carrier family 4 member 3" P48751 2 219627394-219641980 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 283.1;ovary: 124.1" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 207.1;Horizontal cells: 558.6" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "myeloid DC: 1.4;plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 54 "dendritic cells: 5.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063498 Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA063498: AB_2685025" "unprognostic (9.49e-2)" "unprognostic (5.72e-3)" "unprognostic (8.92e-4)" "unprognostic (1.77e-2)" "unprognostic (6.61e-3)" "unprognostic (1.47e-1)" "unprognostic (2.60e-1)" "unprognostic (2.39e-2)" "unprognostic (4.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-1)" "unprognostic (8.15e-3)" "unprognostic (1.97e-1)" "unprognostic (3.27e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.12e-4)" 6.3 16.7 36.1 1.0 36.6 0.4 3.9 21.2 32.1 11.4 6.3 2.9 0.7 15.3 2.7 3.2 9.3 2.3 283.1 31.7 34.5 9.3 0.3 1.6 0.9 44.1 20.7 124.1 3.9 7.7 41.4 2.7 43.1 10.4 0.2 13.0 3.8 5.3 0.9 2.0 1.1 3.7 10.6 3.3 2.7 14.2 32.7 1.0 2.5 0.6 0.6 2.6 4.7 18.0 6.9 0.2 2.3 6.8 0.4 0.4 4.9 4.1 4.2 5.4 3.8 4.8 3.8 0.0 1.6 1.5 9.3 3.8 1.2 7.3 1.6 0.0 1.0 0.0 0.1 0.1 1.1 0.1 0.3 3.1 7.0 0.0 2.1 13.4 0.0 0.0 0.3 0.0 1.6 2.3 0.0 0.0 3.8 0.2 5.5 0.0 0.0 0.0 3.7 1.5 1.3 6.7 2.7 6.9 3.7 7.2 0.7 1.7 0.0 3.4 6.0 0.0 3.3 0.0 0.0 0.0 2.7 0.0 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 36.1 36.6 21.2 32.1 31.7 34.5 44.1 20.7 43.1 10.6 32.7 18.0 0.3 0.0 0.0 19.2 0.2 0.3 0.7 1.5 0.0 14.4 2.2 4.8 207.1 0.0 0.8 1.8 0.0 11.4 13.5 0.0 1.9 3.0 2.3 0.9 3.5 1.8 0.0 0.0 11.5 1.7 3.0 10.4 0.0 1.4 0.0 38.3 0.0 0.0 1.8 558.6 32.7 0.0 0.0 0.3 5.6 25.6 15.2 1.1 0.0 3.7 1.3 7.6 0.0 3.5 0.6 1.1 0.0 22.6 0.0 0.4 0.0 0.3 0.2 7.5 6.6 3.9 3.5 0.6 1.2 0.0 0.9 13.8 0.1 8.7 0.0 0.1 SLC5A9 SGLT4 ENSG00000117834 "Solute carrier family 5 member 9" Q2M3M2 1 48222685-48248644 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 43.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 22.4;Proximal enterocytes: 84.0" "Cancer enhanced" "Detected in many" "liver cancer: 4.1;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA050263 Approved "Actin filaments,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Actin filaments" Cytosol "HPA050263: " "unprognostic (3.09e-3)" "unprognostic (1.89e-1)" "unprognostic (6.75e-2)" "unprognostic (5.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.35e-3)" "unprognostic (3.64e-2)" "unprognostic (4.59e-2)" "unprognostic (3.60e-2)" "unprognostic (1.59e-1)" "unprognostic (7.42e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (4.56e-1)" "unprognostic (2.11e-1)" "unprognostic (4.30e-3)" "unprognostic (1.06e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.8 43.3 0.1 1.2 0.2 0.1 2.5 0.0 0.0 0.0 3.8 7.8 3.0 0.0 0.2 0.2 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.8 0.1 1.1 42.0 0.0 0.0 0.0 0.5 0.5 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.3 0.2 22.4 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 2.8 0.0 0.0 0.0 0.0 0.0 3.1 1.9 0.5 6.3 0.5 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.5 4.5 0.0 0.7 4.4 0.1 0.0 0.2 2.9 0.0 1.3 0.0 11.0 0.3 0.3 0.0 1.9 0.1 0.0 0.0 7.5 2.9 0.1 1.7 0.4 0.0 0.0 84.0 4.1 0.0 0.0 0.0 0.2 0.1 0.6 0.3 0.0 0.0 0.0 0.1 0.0 3.0 0.0 SLC6A11 GAT3 ENSG00000132164 "Solute carrier family 6 member 11" P48066 3 10816201-10940714 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 153.3" "Cell type enhanced" "Detected in some" "Astrocytes: 85.2;Excitatory neurons: 13.7;Inhibitory neurons: 25.8;Muller glia cells: 26.4;Oligodendrocyte precursor cells: 23.1" "Cancer enhanced" "Detected in many" "glioma: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 13.5;Hep G2: 16.0;hTCEpi: 11.9;NTERA-2: 6.7;T-47d: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037981 Supported Supported Uncertain Nucleoplasm,Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Vesicles "HPA037981: AB_10671383" "unprognostic (6.04e-2)" "unprognostic (8.01e-2)" "unprognostic (1.21e-7)" "unprognostic (8.60e-2)" "unprognostic (8.68e-2)" "unprognostic (9.72e-3)" "unprognostic (6.39e-3)" "unprognostic (9.77e-2)" "unprognostic (2.35e-1)" "unprognostic (3.92e-2)" "unprognostic (8.78e-2)" "unprognostic (1.51e-3)" "unprognostic (6.06e-2)" "unprognostic (4.44e-2)" "unprognostic (9.83e-2)" "unprognostic (2.31e-2)" 0.0 0.0 50.5 0.0 78.7 0.0 1.1 57.3 32.6 0.7 9.6 0.0 0.0 0.5 0.1 8.2 0.5 0.0 0.0 22.6 96.6 0.0 0.1 0.0 0.0 60.0 128.4 0.0 0.1 0.5 0.3 0.4 61.9 0.7 0.0 11.0 1.0 0.0 0.2 5.7 0.0 0.1 41.8 0.4 0.0 1.4 153.3 0.0 0.0 0.0 0.1 0.4 1.8 21.1 5.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.5 0.0 2.2 0.0 0.0 0.2 0.3 0.0 16.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.9 4.5 3.9 0.1 0.0 0.1 5.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.5 78.7 57.3 32.6 22.6 96.6 60.0 128.4 61.9 41.8 153.3 21.1 0.0 0.0 0.0 85.2 0.0 1.3 0.7 0.3 4.0 8.4 0.9 0.9 1.4 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 13.7 0.0 7.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 25.8 0.0 0.0 0.0 0.8 0.9 3.4 0.2 0.0 6.5 0.0 26.4 0.0 23.1 0.8 0.2 0.0 6.8 0.0 0.5 0.0 0.0 0.0 1.5 0.0 0.6 0.1 0.6 1.8 10.6 3.7 1.0 0.1 0.0 0.0 1.7 SLC6A17 ENSG00000197106 "Solute carrier family 6 member 17" Q9H1V8 1 110150494-110202202 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 52.9;pituitary gland: 25.3" "Group enriched" "Detected in some" 5 "Excitatory neurons: 60.6;Inhibitory neurons: 59.4" "Cancer enriched" "Detected in some" 9 "melanoma: 17.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-MEL-30: 36.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008043, HPA008044" Enhanced Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA008043: , HPA008044: AB_1857192" "unprognostic (1.13e-1)" "unprognostic (1.37e-3)" "unprognostic (5.52e-3)" "unprognostic (3.00e-2)" "unprognostic (1.17e-1)" "unprognostic (4.88e-2)" "unprognostic (6.11e-3)" "unprognostic (3.87e-3)" "unprognostic (1.70e-2)" "unprognostic (1.80e-1)" "unprognostic (1.68e-2)" "unprognostic (2.94e-1)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (9.76e-2)" "unprognostic (1.38e-3)" "unprognostic (1.68e-3)" 0.4 5.9 21.6 0.2 26.3 0.1 0.3 1.2 52.9 0.1 0.0 0.3 0.0 0.1 1.0 0.4 0.1 0.1 0.1 20.1 9.6 1.3 0.0 0.1 0.0 13.7 8.2 0.0 1.4 8.8 25.3 0.8 10.5 0.1 0.1 6.0 0.6 0.1 0.1 6.2 0.1 0.1 0.0 0.0 0.7 1.8 24.8 0.0 0.3 0.1 0.0 0.1 0.1 15.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 5.5 0.5 2.1 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 1.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.8 6.2 1.9 36.0 1.0 0.9 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 7.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 26.3 1.2 52.9 20.1 9.6 13.7 8.2 10.5 0.0 24.8 15.7 0.0 0.0 0.0 2.6 0.0 0.5 0.0 0.1 0.0 5.1 0.2 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 1.2 0.0 0.0 0.5 0.0 0.0 60.6 0.0 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 59.4 0.0 4.1 0.0 0.0 0.7 0.0 0.0 10.6 3.7 0.0 0.7 0.0 4.5 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.7 0.4 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 0.0 SLC6A9 GLYT1 ENSG00000196517 "Solute carrier family 6 member 9" P48067 1 43991500-44031467 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.4;skin 1: 46.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.7;Distal enterocytes: 17.8;Erythroid cells: 33.1;Ionocytes: 20.3" "Cancer enhanced" "Detected in all" "glioma: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.3;hTCEpi: 106.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013977 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA013977: AB_1849835" "unprognostic (2.73e-2)" "unprognostic (1.92e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (5.98e-2)" "unprognostic (6.83e-3)" "unprognostic (3.06e-2)" "unprognostic (9.72e-2)" "unprognostic (1.85e-2)" "unprognostic (3.52e-2)" "unprognostic (1.41e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (5.93e-4)" "unprognostic (5.36e-3)" "unprognostic (1.59e-1)" "unprognostic (2.53e-1)" "unprognostic (1.20e-2)" 3.9 31.0 21.7 4.9 45.5 10.8 4.6 53.2 24.2 12.1 6.3 11.0 2.3 7.4 1.1 23.1 9.5 4.8 2.1 16.1 31.3 4.3 2.3 11.6 1.1 66.3 43.5 2.9 8.2 2.8 1.7 1.4 63.6 3.9 6.3 17.2 11.5 5.5 1.1 46.6 6.0 9.1 45.6 1.9 7.4 1.1 45.9 1.4 5.3 0.6 4.3 12.3 25.1 72.4 19.7 13.7 7.1 18.0 11.2 3.7 15.6 14.7 41.0 24.3 30.1 4.8 7.5 0.3 1.6 42.9 0.0 62.3 11.0 12.5 5.0 0.1 1.8 17.1 33.9 5.8 50.3 3.8 0.7 11.3 106.6 11.9 28.5 15.3 0.6 12.3 13.0 48.5 1.0 10.4 2.9 0.1 5.4 7.4 19.1 2.2 0.0 22.9 2.3 2.2 4.4 4.2 7.4 35.3 7.0 1.7 9.1 10.3 0.2 2.8 11.0 2.4 8.0 53.1 39.2 4.4 9.2 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 45.5 53.2 24.2 16.1 31.3 66.3 43.5 63.6 45.6 45.9 72.4 1.5 0.0 2.0 5.9 1.1 7.5 0.9 3.2 8.0 30.7 2.2 0.9 0.7 4.3 2.2 1.8 16.7 0.5 0.5 17.8 0.0 3.7 5.9 4.8 0.4 0.7 0.0 33.1 2.2 8.9 1.0 0.9 1.5 2.7 0.0 0.0 0.0 0.3 0.3 1.7 1.5 2.7 20.3 0.0 1.0 0.8 1.5 0.1 3.6 0.0 1.0 1.2 0.0 3.0 16.4 4.2 3.0 1.5 1.3 2.0 9.1 1.1 12.5 11.1 6.6 0.1 10.0 0.1 0.4 8.9 12.9 0.5 0.3 1.2 2.6 3.2 SLC7A10 asc-1 ENSG00000130876 "Solute carrier family 7 member 10" Q9NS82 19 33208664-33225850 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adipose tissue: 31.8;brain: 12.7;breast: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 40.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 1.9;HHSteC: 1.1;HSkMC: 1.6;THP-1: 3.9;U-2 OS: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041884, HPA057036" Uncertain Uncertain Nucleoplasm,Nucleoli NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli" "HPA041884: AB_10794494, HPA057036: AB_2683317" "unprognostic (1.85e-2)" "unprognostic (1.69e-3)" "unprognostic (2.79e-2)" "unprognostic (1.79e-6)" "unprognostic (1.16e-1)" "unprognostic (2.08e-1)" "unprognostic (1.31e-1)" "unprognostic (4.98e-3)" "unprognostic (4.64e-2)" "unprognostic (1.96e-1)" "unprognostic (3.28e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-2)" "unprognostic (1.34e-3)" "unprognostic (8.91e-2)" "unprognostic (3.47e-1)" "unprognostic (2.18e-2)" 31.8 0.3 7.9 0.1 9.7 0.0 12.7 10.1 11.1 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.3 9.2 0.5 0.0 0.0 0.2 8.5 12.4 0.0 0.1 0.0 0.0 0.2 8.4 0.0 0.0 0.5 0.8 0.0 0.1 0.2 0.5 0.0 6.0 0.0 0.1 0.5 12.7 0.0 0.5 0.4 0.3 0.3 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 9.7 10.1 11.1 7.3 9.2 8.5 12.4 8.4 6.0 12.7 5.1 0.1 0.0 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.8 0.0 2.4 0.0 9.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 SLC9A4 NHE4 ENSG00000180251 "Solute carrier family 9 member A4" Q6AI14 2 102473226-102533972 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "stomach 1: 53.8" "Group enriched" "Detected in some" 12 "Collecting duct cells: 25.8;Gastric mucus-secreting cells: 54.0" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.3;OE19: 6.8;RT4: 4.1" "Group enriched" "Detected in some" 18 "hippocampal formation: 10.6;olfactory bulb: 6.8" "Low region specificity" "Detected in single" HPA036096 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Plasma membrane" "HPA036096: AB_2674939" "unprognostic (1.41e-1)" "unprognostic (3.76e-2)" "unprognostic (9.31e-2)" "unprognostic (3.09e-3)" "unprognostic (7.58e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (5.35e-1)" "unprognostic (9.44e-3)" "unprognostic (3.26e-2)" "unprognostic (1.30e-1)" "unprognostic (2.46e-2)" "unprognostic (3.12e-1)" "unprognostic (5.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.98e-2)" 0.0 0.0 0.4 0.1 0.5 0.8 0.2 0.7 0.7 0.3 0.0 0.0 2.0 0.1 0.1 1.5 0.1 1.2 0.6 0.4 0.4 8.6 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.4 1.3 0.5 1.4 0.4 0.0 0.0 0.0 0.2 53.8 0.3 0.2 0.1 0.1 0.0 0.5 0.4 0.1 0.6 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 1.3 0.0 0.1 0.1 0.0 0.0 0.0 2.3 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.5 6.8 0.2 0.0 0.2 0.1 0.0 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.7 0.7 0.4 0.4 0.1 0.1 0.2 0.0 0.2 0.6 0.0 3.2 3.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.4 0.0 0.9 25.8 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 54.0 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 2.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.6 0.8 0.0 0.0 0.1 0.4 0.0 0.3 0.3 SLC9A9 "FLJ35613, NHE9" ENSG00000181804 "Solute carrier family 9 member A9" Q8IVB4 3 143265222-143848485 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 149.8;Inhibitory neurons: 159.5;Microglial cells: 396.3;Oligodendrocyte precursor cells: 272.9;Oligodendrocytes: 431.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 19.3;ASC TERT1: 24.9;HSkMC: 17.6;Karpas-707: 62.8;RPMI-8226: 30.4;U-266/70: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058234 Approved NA NA 280000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA058234: AB_2683648" "unprognostic (8.22e-2)" "unprognostic (6.88e-2)" "unprognostic (7.23e-3)" "unprognostic (1.65e-1)" "unprognostic (3.65e-2)" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "prognostic favorable (8.18e-4)" "unprognostic (2.66e-1)" "unprognostic (1.35e-3)" "unprognostic (7.73e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (5.57e-7)" "unprognostic (5.01e-2)" "unprognostic (4.69e-2)" "unprognostic (1.56e-1)" "unprognostic (4.28e-2)" 12.8 5.1 9.7 8.8 14.4 2.0 5.3 12.5 11.3 6.9 6.9 7.3 3.0 4.2 3.7 12.8 6.8 9.6 5.4 9.9 16.3 2.3 7.1 5.9 14.7 20.4 13.5 7.9 1.0 3.0 3.4 15.9 19.5 8.8 5.8 1.3 4.5 8.5 2.1 7.7 7.0 8.0 14.4 13.1 5.0 1.8 13.8 15.5 3.5 5.0 13.5 11.4 7.7 18.2 0.5 0.5 0.8 1.0 19.3 24.9 0.3 1.0 6.6 0.5 3.1 0.0 0.2 3.0 0.2 2.9 1.5 0.7 0.9 1.9 0.8 12.8 0.2 1.6 0.4 0.0 2.2 0.8 1.3 17.6 5.2 0.7 0.9 1.1 0.3 2.3 0.0 62.8 4.2 0.0 1.5 0.0 0.2 0.0 0.5 2.6 0.1 30.4 0.0 0.5 0.4 0.0 1.5 0.0 0.0 0.4 0.2 0.6 0.0 2.4 0.6 2.8 1.4 29.1 0.1 0.1 4.3 0.4 1.2 0.2 6.2 0.7 4.7 10.6 4.0 3.3 4.9 7.5 8.4 3.7 2.7 4.0 0.5 4.2 9.0 0.6 9.3 4.8 9.7 14.4 12.5 11.3 9.9 16.3 20.4 13.5 19.5 14.4 13.8 18.2 4.5 0.0 1.1 149.8 13.2 3.7 10.4 8.7 22.8 0.2 0.6 1.3 1.5 0.0 3.4 3.7 2.1 0.5 10.4 0.0 0.0 1.0 4.8 0.8 10.1 4.4 0.0 9.9 25.6 0.2 0.5 26.5 7.1 0.8 0.0 0.7 21.8 0.0 55.4 0.0 159.5 0.0 6.1 30.5 9.9 4.4 9.3 31.0 7.2 396.3 24.3 2.8 13.4 272.9 431.8 0.8 0.1 7.2 10.9 11.1 0.0 0.4 1.6 0.1 0.0 18.0 7.0 0.3 0.4 23.9 5.1 1.1 19.7 3.7 0.1 3.9 SLCO3A1 "OATP-D, OATP3A1, SLC21A11" ENSG00000176463 "Solute carrier organic anion transporter family member 3A1" Q9UIG8 15 91853708-92172435 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 625.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 63.1;HaCaT: 95.5;HMC-1: 55.3;RPMI-8226: 44.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066327 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA066327: AB_2732743" "unprognostic (1.05e-3)" "prognostic favorable (8.61e-4)" "unprognostic (5.40e-2)" "prognostic unfavorable (6.57e-6)" "unprognostic (1.03e-1)" "unprognostic (7.39e-2)" "unprognostic (2.16e-1)" "unprognostic (1.57e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.42e-2)" "unprognostic (1.49e-2)" "unprognostic (2.64e-2)" "unprognostic (3.06e-2)" "unprognostic (1.86e-1)" "unprognostic (7.17e-2)" "unprognostic (1.62e-2)" 11.7 6.2 19.3 6.8 29.5 9.6 8.6 33.7 23.0 8.4 24.1 4.0 1.8 5.3 3.3 10.6 6.9 6.3 26.4 20.3 20.2 10.6 2.9 13.8 6.3 30.2 29.6 4.2 3.0 15.7 6.7 1.0 27.8 4.3 3.4 1.5 4.7 6.2 5.8 15.7 4.2 5.0 22.5 11.1 4.6 17.9 26.1 2.6 10.6 9.6 6.2 8.6 10.8 39.5 10.1 12.3 13.9 0.2 20.9 12.6 0.2 4.0 3.4 1.6 0.4 0.0 63.1 12.1 5.3 1.3 9.1 95.5 2.7 6.3 0.2 8.8 0.4 27.8 20.9 0.0 0.9 0.6 55.3 5.7 6.7 2.9 7.3 5.4 0.0 3.6 0.0 0.1 0.0 1.8 0.0 5.1 3.7 0.2 1.7 0.0 1.1 44.0 13.4 10.0 2.0 3.3 10.5 0.9 0.1 2.0 0.1 8.5 0.0 3.3 4.7 0.0 10.3 25.5 16.0 11.7 4.2 16.9 6.0 4.3 2.4 6.9 1.4 2.0 1.1 0.2 1.5 1.7 1.6 0.0 0.5 0.6 7.5 0.3 1.7 0.0 2.7 0.6 19.3 29.5 33.7 23.0 20.3 20.2 30.2 29.6 27.8 22.5 26.1 39.5 53.5 48.1 32.0 17.0 4.3 39.0 29.3 14.2 22.8 28.1 3.1 13.0 44.0 24.3 16.4 51.5 4.2 0.0 33.1 6.2 1.9 26.6 105.6 15.8 29.0 26.2 37.8 6.1 89.5 8.7 0.1 22.9 0.5 36.2 22.8 94.9 34.6 0.8 4.6 0.0 149.4 7.2 8.2 24.7 95.2 38.5 5.0 34.0 10.6 56.2 43.6 5.2 25.7 20.6 625.8 8.4 11.1 3.0 17.3 41.5 0.0 0.4 22.1 3.1 39.5 17.4 62.0 69.5 11.9 22.6 60.1 0.0 23.3 0.8 7.9 38.2 SLCO4C1 "OATP-H, OATP4C1, OATPX, SLC21A20" ENSG00000173930 "Solute carrier organic anion transporter family member 4C1" Q6ZQN7 5 102233986-102296284 "Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 41.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 49.7;Early spermatids: 21.6;NK-cells: 26.8;Proximal tubular cells: 32.8" "Cancer enriched" "Detected in many" 5 "renal cancer: 22.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 9.5;neutrophil: 9.8" "Group enriched" "Detected in many" 5 "granulocytes: 9.8;NK-cells: 2.6;T-cells: 3.8" "Cell line enhanced" "Detected in some" "Karpas-707: 17.5;RPTEC TERT1: 98.8;U-937: 25.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058249 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA058249: " "unprognostic (1.63e-2)" "unprognostic (2.47e-2)" "unprognostic (4.48e-4)" "unprognostic (5.70e-6)" "unprognostic (7.43e-2)" "unprognostic (7.71e-3)" "unprognostic (3.24e-3)" "unprognostic (2.05e-3)" "unprognostic (2.13e-1)" "unprognostic (7.12e-2)" "unprognostic (3.87e-3)" "unprognostic (5.83e-2)" "prognostic favorable (1.12e-4)" "unprognostic (3.29e-2)" "unprognostic (1.07e-1)" "unprognostic (5.91e-2)" "unprognostic (8.22e-2)" 0.4 0.8 0.2 0.6 0.3 8.6 0.5 0.0 0.4 0.3 0.0 1.0 2.2 0.1 0.2 0.1 0.2 2.3 0.3 0.2 0.0 41.6 7.6 7.8 0.5 0.2 0.0 0.1 0.4 0.1 0.2 0.1 0.2 0.0 0.8 0.1 2.0 3.6 0.1 0.3 1.5 0.1 0.0 1.3 0.6 0.8 0.3 1.0 1.6 0.1 0.2 0.2 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.7 1.1 0.0 1.0 0.2 1.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 17.5 0.0 1.3 0.1 0.3 0.8 0.0 0.0 0.0 0.0 1.2 98.8 0.1 0.7 0.5 0.0 0.3 0.0 2.3 0.0 2.4 0.0 0.0 0.7 0.0 0.0 1.6 0.0 0.0 0.0 25.8 0.1 9.5 1.0 7.3 3.8 0.0 0.3 0.0 0.6 2.1 0.4 0.1 0.2 1.3 9.8 2.6 0.0 0.2 0.0 1.0 0.2 0.3 0.0 0.4 0.2 0.0 0.2 0.0 0.2 0.0 0.3 0.3 0.1 6.4 49.7 0.3 0.6 0.0 0.1 1.2 0.0 0.0 1.8 0.3 0.3 1.5 6.4 5.5 0.0 0.0 9.6 1.4 1.9 0.2 21.6 0.0 0.1 0.3 0.0 5.7 9.1 0.8 0.0 0.3 0.0 1.6 5.7 0.0 0.4 11.0 0.2 0.0 6.6 0.1 2.0 0.6 0.3 2.6 0.3 2.4 0.0 1.0 3.2 0.0 26.8 1.5 0.3 0.3 0.1 0.0 1.4 0.0 1.8 32.8 3.1 0.0 0.0 0.1 0.1 2.5 2.4 0.0 0.0 0.0 3.4 0.1 1.1 0.4 SLFN11 FLJ34922 ENSG00000172716 "Schlafen family member 11" Q7Z7L1 17 35350305-35373701 "Predicted intracellular proteins" "Antiviral defense, DNA damage, Immunity" "Helicase, Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 70.6;dendritic cells: 39.9;Endothelial cells: 38.8;Langerhans cells: 53.0;Macrophages: 47.0;Smooth muscle cells: 38.8;T-cells: 37.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 118.2" "Low region specificity" "Detected in many" "HPA023030, HPA062062" Uncertain Supported Nucleoplasm,Cytosol No NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA023030: AB_1856613, HPA062062: AB_2684673" "unprognostic (1.93e-2)" "unprognostic (2.56e-1)" "unprognostic (3.04e-2)" "unprognostic (1.03e-2)" "unprognostic (3.48e-3)" "unprognostic (1.01e-1)" "unprognostic (5.19e-2)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (9.93e-10)" "unprognostic (1.65e-1)" "unprognostic (5.71e-3)" "unprognostic (6.33e-2)" "unprognostic (8.81e-3)" 31.7 8.2 5.6 20.0 6.1 12.8 17.1 6.4 5.2 21.1 8.2 10.2 6.2 12.1 42.2 8.4 20.6 18.3 20.0 6.0 8.0 6.4 6.8 37.7 21.2 9.5 6.3 23.1 5.4 6.1 6.5 10.5 9.7 9.1 11.1 1.4 11.8 12.3 7.3 5.2 13.9 19.1 7.6 23.3 9.0 2.7 11.0 22.9 24.1 19.0 20.9 17.9 12.6 9.4 29.3 25.6 0.1 0.0 25.4 72.0 0.4 35.3 25.2 59.9 103.9 0.0 0.0 0.2 0.6 46.4 18.8 13.9 78.8 0.0 72.1 16.6 94.2 63.0 0.3 0.0 33.0 82.4 0.1 29.5 0.9 66.5 0.2 0.0 99.4 46.8 0.1 0.3 10.1 0.0 118.2 66.4 0.6 0.0 0.1 98.9 73.3 0.2 0.7 13.8 0.2 0.1 0.0 13.0 0.1 0.0 20.7 58.6 52.1 16.3 0.4 61.9 53.7 2.3 1.0 0.2 12.2 70.3 36.0 0.5 18.2 2.1 6.1 27.6 8.4 4.6 3.8 5.5 14.0 1.5 2.8 4.1 1.4 3.1 18.2 19.4 6.3 8.7 5.6 6.1 6.4 5.2 6.0 8.0 9.5 6.3 9.7 7.6 11.0 9.4 70.6 0.0 5.2 0.3 19.5 7.5 1.1 1.1 5.7 0.4 6.7 2.8 9.2 1.5 2.7 1.8 0.0 1.4 39.9 0.1 0.0 0.0 1.4 5.9 16.0 38.8 0.0 9.9 0.3 0.6 0.5 29.2 6.6 2.2 3.8 0.3 15.0 0.4 32.8 0.0 2.6 0.1 0.0 36.5 53.0 1.7 10.2 47.0 12.4 17.8 17.2 0.3 3.1 0.0 0.1 0.1 1.2 3.0 24.7 1.3 0.1 0.2 13.3 0.1 6.6 7.9 38.8 0.0 0.2 1.9 8.5 0.8 37.3 7.7 0.1 0.7 SLITRK4 DKFZp547M2010 ENSG00000179542 "SLIT and NTRK like family member 4" Q8IW52 X 143622790-143636101 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.1;brain: 9.0;skeletal muscle: 8.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.3;Granulosa cells: 33.9;Inhibitory neurons: 48.8;Leydig cells: 49.7;Oligodendrocyte precursor cells: 29.7;Sertoli cells: 26.3" "Cancer enriched" "Detected in many" 4 "renal cancer: 3.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 11.6" "Group enriched" "Detected in many" 64 "dendritic cells: 3.2;granulocytes: 11.6;monocytes: 4.1" "Cell line enhanced" "Detected in some" "HeLa: 5.4;HHSteC: 2.7;LHCN-M2: 2.0;T-47d: 8.8;U-2 OS: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000431 Enhanced NA NA 420000 "Cluster 38: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000431: AB_2665991" "unprognostic (1.72e-1)" "unprognostic (2.11e-2)" "unprognostic (2.63e-2)" "unprognostic (1.15e-3)" "unprognostic (4.09e-1)" "unprognostic (1.75e-2)" "unprognostic (3.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.97e-2)" "unprognostic (1.86e-1)" "unprognostic (3.64e-2)" "unprognostic (9.61e-2)" "unprognostic (6.02e-2)" "unprognostic (1.02e-5)" "unprognostic (1.29e-2)" "unprognostic (7.75e-2)" "unprognostic (9.23e-3)" 4.2 11.1 4.9 0.3 6.5 1.3 2.0 9.0 8.1 5.1 0.0 0.2 0.1 1.2 2.8 0.6 0.4 0.3 2.2 6.9 1.3 3.0 0.0 0.4 0.3 0.0 1.4 3.6 1.0 0.4 0.0 0.4 0.0 1.6 0.3 0.4 1.0 1.3 8.3 1.7 0.2 0.9 0.0 0.1 0.1 1.1 2.8 0.6 0.3 4.7 0.0 0.3 0.3 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 2.7 0.4 0.5 1.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.9 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 4.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.0 0.9 4.9 6.5 9.0 8.1 6.9 1.3 0.0 1.4 0.0 0.0 2.8 1.4 0.6 0.0 0.0 3.3 0.0 12.0 0.6 0.0 0.0 3.3 3.2 2.2 1.3 2.8 0.0 3.7 0.0 0.0 0.0 0.1 1.9 0.0 0.5 0.4 2.1 1.1 0.0 0.0 52.3 1.5 0.0 11.0 0.0 1.6 0.0 33.9 0.0 0.0 4.1 0.0 48.8 0.0 0.0 4.3 18.5 2.1 49.7 4.7 21.4 1.0 6.6 0.0 1.0 29.7 2.6 0.7 0.0 16.1 0.0 1.4 0.0 0.9 0.0 0.4 26.3 4.1 4.5 0.4 1.1 0.0 11.6 0.0 1.1 6.4 0.0 0.6 SLN "MGC12301, MGC125854, MGC125855" ENSG00000170290 Sarcolipin O00631 11 107707378-107719693 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 8190.2;tongue: 3399.6" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 730.3;Muller glia cells: 462.5;Skeletal myocytes: 225.1" "Group enriched" "Detected in many" 5 "glioma: 21.6;head and neck cancer: 22.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.1;HSkMC: 2.5;Karpas-707: 1.2;PC-3: 1.1;SuSa: 2.5;U-2 OS: 1.1" CAB011628 Approved Microtubules NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Microtubules "CAB011628: AB_2195046" "unprognostic (6.85e-2)" "unprognostic (6.18e-8)" "unprognostic (2.60e-1)" "unprognostic (3.66e-2)" "unprognostic (2.40e-3)" "unprognostic (4.12e-3)" "unprognostic (5.28e-3)" "unprognostic (1.31e-2)" "unprognostic (2.76e-1)" "unprognostic (6.35e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.52e-9)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "unprognostic (5.09e-4)" "unprognostic (3.77e-2)" 5.1 8.3 2.8 0.0 3.4 0.0 2.1 3.9 7.8 0.2 1.3 4.7 0.3 0.2 0.8 149.2 0.7 0.3 975.1 2.4 1.4 2.6 0.7 6.4 0.2 1.5 2.3 0.6 1.8 0.2 0.7 1.3 2.3 37.0 0.1 60.7 59.4 0.3 8190.2 4.4 1.5 1.4 1.3 0.3 0.8 1.3 1.4 2.7 2.0 3399.6 0.9 0.4 1.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 3.4 3.9 7.8 2.4 1.4 1.5 2.3 2.3 1.3 1.4 2.0 0.0 0.0 0.0 0.0 0.0 1.0 1.2 0.0 0.0 2.4 0.0 0.0 730.3 0.0 0.0 0.0 2.1 1.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 10.5 0.0 0.0 0.3 0.4 1.9 42.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.3 0.0 0.0 0.0 0.0 1.1 8.8 0.0 1.0 0.0 0.0 0.0 462.5 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.2 0.0 0.4 0.0 19.9 0.0 225.1 40.5 0.1 0.0 0.0 1.4 5.7 1.0 0.0 0.0 0.1 SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1039.2;skin 1: 858.5" "Group enriched" "Detected in some" 16 "Squamous epithelial cells: 20.8;Suprabasal keratinocytes: 65.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 66.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.3;MCF7: 1.5;RT4: 1.1;T-47d: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" NA NA 7700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA050967: AB_2681293" "unprognostic (1.22e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (7.32e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-4)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" 0.9 0.6 0.1 0.0 0.0 0.0 11.3 0.7 0.5 105.0 0.0 0.3 0.0 0.2 0.0 1039.2 0.2 0.2 0.4 0.1 0.0 0.2 0.5 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 70.1 0.0 1.4 858.5 0.3 0.0 0.0 0.2 0.8 0.3 0.1 0.9 0.2 0.0 17.4 0.3 206.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.6 0.0 0.0 1.8 1.5 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.8 65.8 0.0 0.0 0.0 0.0 0.8 SMAD9 "MADH6, MADH9, SMAD8, SMAD8/9" ENSG00000120693 "SMAD family member 9" O15198 13 36844831-36920765 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 38.7" "Cell type enhanced" "Detected in many" "Astrocytes: 48.0;Enteroendocrine cells: 51.6;Glandular and luminal cells: 73.4;Hepatic stellate cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 12.9;HEK 293: 12.3;SH-SY5Y: 40.2" "Low region specificity" "Detected in all" "CAB009119, HPA031162" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "CAB009119: AB_2286517, HPA031162: AB_2673767" "unprognostic (2.88e-1)" "unprognostic (1.38e-1)" "unprognostic (9.68e-3)" "unprognostic (3.50e-3)" "prognostic favorable (5.99e-4)" "unprognostic (1.30e-1)" "unprognostic (1.34e-1)" "unprognostic (3.71e-3)" "unprognostic (4.23e-2)" "unprognostic (6.62e-2)" "unprognostic (4.07e-3)" "unprognostic (3.74e-2)" "unprognostic (9.70e-2)" "unprognostic (1.55e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.92e-4)" "unprognostic (2.47e-2)" 4.0 2.6 10.7 2.8 7.8 0.1 1.6 10.7 6.8 4.8 1.2 5.1 2.3 8.9 9.8 4.2 4.3 7.0 5.6 10.3 16.3 3.2 0.9 4.9 2.2 17.2 10.9 9.2 0.9 2.4 1.9 6.5 16.9 13.9 5.3 7.0 21.0 11.2 3.0 1.5 2.5 6.7 15.5 0.9 3.7 2.3 9.6 0.5 38.7 5.1 2.9 3.3 2.1 21.3 0.0 0.1 0.8 8.6 2.6 1.1 0.3 10.5 1.1 2.7 1.7 0.0 0.2 0.2 7.2 12.9 0.9 0.4 9.3 0.2 2.8 0.3 12.3 0.0 4.4 6.6 2.4 0.8 0.1 4.4 0.8 0.0 0.0 5.7 5.3 1.1 0.1 0.0 6.0 0.6 0.1 0.8 1.2 0.3 1.1 0.2 9.2 0.0 0.0 1.5 7.6 40.2 1.9 0.2 0.5 2.3 0.6 0.4 9.6 4.0 3.5 2.4 2.6 0.1 0.0 0.1 2.8 0.3 0.6 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 10.7 7.8 10.7 6.8 10.3 16.3 17.2 10.9 16.9 15.5 9.6 21.3 22.5 28.9 11.5 48.0 0.4 2.8 4.3 1.8 1.8 13.1 2.5 2.2 5.9 2.8 6.9 11.0 4.2 0.2 0.2 3.3 1.9 0.3 0.1 30.3 14.0 26.7 51.6 0.0 18.1 0.2 0.6 11.6 3.6 73.4 0.0 19.7 43.9 0.1 0.1 0.0 33.0 15.6 8.2 2.2 1.9 0.3 18.6 1.1 0.0 31.9 0.0 20.4 0.0 14.1 39.3 0.5 3.4 15.1 0.0 17.2 0.0 7.3 1.6 3.2 0.0 7.2 10.1 1.2 14.1 0.2 1.8 0.3 1.4 0.5 5.7 1.2 SMAP2 SMAP1L ENSG00000084070 "Small ArfGAP2" Q8WU79 1 40344850-40423326 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 216.3" "Cell type enhanced" "Detected in all" "B-cells: 338.4;dendritic cells: 258.0;Kupffer cells: 284.4;Macrophages: 256.8;monocytes: 291.7;Plasma cells: 224.4;T-cells: 199.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 177.1;THP-1: 302.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021466, HPA024424" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA021466: AB_2239737, HPA024424: AB_1857259" "unprognostic (1.65e-1)" "prognostic favorable (6.55e-4)" "unprognostic (7.17e-2)" "unprognostic (1.40e-3)" "unprognostic (4.32e-1)" "prognostic favorable (5.34e-5)" "prognostic unfavorable (2.53e-4)" "unprognostic (9.05e-2)" "unprognostic (2.27e-1)" "unprognostic (2.24e-1)" "unprognostic (4.00e-3)" "unprognostic (2.65e-1)" "unprognostic (1.02e-2)" "unprognostic (1.88e-2)" "unprognostic (5.45e-2)" "unprognostic (6.23e-2)" "unprognostic (1.24e-1)" 65.3 24.0 44.2 136.7 50.7 80.9 33.3 35.7 54.3 43.9 33.8 33.5 17.5 17.9 14.1 26.2 30.7 46.3 17.2 52.1 48.2 19.2 73.5 58.4 205.8 41.8 41.1 17.1 23.8 27.4 43.9 38.0 42.9 20.0 32.1 48.5 29.5 19.0 30.0 33.3 99.2 40.1 38.3 216.3 41.8 17.0 48.0 158.3 19.2 21.2 199.5 52.2 19.3 47.2 25.1 9.3 22.0 22.2 31.4 60.0 12.2 38.4 34.7 38.9 37.9 11.7 16.8 93.1 18.4 34.4 16.0 10.2 41.1 29.4 53.3 177.1 34.8 51.7 14.2 25.5 28.1 54.3 153.7 51.7 24.3 50.4 21.6 19.1 22.4 71.6 94.9 95.2 47.0 16.8 79.3 51.2 13.4 24.7 84.7 30.3 20.4 96.3 18.9 28.9 37.1 17.1 18.1 46.1 29.9 16.8 14.8 302.3 12.4 42.8 17.6 40.2 29.9 31.3 37.1 75.9 38.8 53.1 28.2 12.4 87.7 102.0 14.5 153.8 18.2 43.7 23.3 22.1 49.3 58.6 32.4 30.1 195.4 31.6 195.8 9.3 35.5 52.1 44.2 50.7 35.7 54.3 52.1 48.2 41.8 41.1 42.9 38.3 48.0 47.2 12.8 25.6 28.4 10.1 338.4 18.0 11.4 8.5 4.0 34.7 17.5 13.6 15.3 30.0 24.5 7.3 22.9 5.5 258.0 11.0 5.9 12.6 12.7 78.2 15.8 18.7 9.5 66.7 75.7 18.7 9.6 17.1 26.0 25.0 28.4 10.4 38.6 66.3 43.5 26.9 52.4 9.8 12.2 284.4 140.1 19.5 5.3 256.8 28.4 89.9 291.7 15.0 129.8 54.8 33.6 17.1 8.9 4.9 224.4 9.6 10.0 9.1 70.2 25.6 32.9 12.8 27.9 15.9 11.6 12.7 17.8 4.1 199.9 14.6 9.5 14.6 SMC2 "CAP-E, hCAP-E, SMC2L1" ENSG00000136824 "Structural maintenance of chromosomes 2" O95347 9 104094260-104141419 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 25.7" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071309 Approved Supported Nucleoplasm,Nucleoli Yes No 26000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA071309: AB_2686385" "unprognostic (1.51e-1)" "unprognostic (2.01e-3)" "unprognostic (2.26e-2)" "unprognostic (2.23e-2)" "unprognostic (3.04e-1)" "unprognostic (1.05e-1)" "unprognostic (5.57e-3)" "unprognostic (2.59e-3)" "unprognostic (1.47e-2)" "unprognostic (4.35e-1)" "unprognostic (1.24e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (8.02e-3)" "unprognostic (1.65e-1)" "unprognostic (1.12e-1)" "unprognostic (1.32e-2)" 5.2 4.1 2.8 11.3 4.0 18.4 6.6 4.4 3.3 7.5 1.3 8.2 7.5 6.0 2.6 7.3 4.7 4.0 7.9 2.2 4.0 6.3 4.7 4.5 16.0 4.9 3.7 4.7 3.5 5.7 1.5 6.9 4.1 4.2 8.8 5.6 3.1 4.7 2.2 7.4 7.6 5.4 3.5 7.2 6.1 12.0 3.5 25.7 7.6 5.4 15.9 4.9 3.2 5.0 59.3 45.0 49.4 45.9 10.3 14.9 46.2 53.5 25.4 46.9 39.4 39.3 44.9 112.6 25.2 27.7 40.5 97.6 72.3 34.8 63.2 71.6 30.3 67.9 68.8 25.5 2.7 41.5 65.6 9.8 7.0 63.7 25.7 15.9 33.7 71.2 55.8 89.8 43.0 28.9 109.1 21.3 42.9 47.6 34.8 72.0 141.3 42.2 20.1 21.1 46.5 35.9 63.8 29.6 15.5 20.5 59.5 28.0 27.1 56.8 59.1 79.3 67.9 32.6 118.2 64.6 36.8 59.8 70.3 15.0 2.2 2.5 4.8 5.9 5.4 7.3 4.4 4.8 2.6 7.9 5.0 5.8 0.3 7.0 7.4 4.4 6.0 2.4 2.8 4.0 4.4 3.3 2.2 4.0 4.9 3.7 4.1 3.5 3.5 5.0 19.6 25.6 11.9 6.5 19.9 27.3 16.4 27.6 11.4 39.7 16.6 19.3 45.1 7.2 17.8 16.5 8.4 54.3 15.2 13.7 35.2 18.9 40.0 114.6 21.6 21.4 4.9 95.3 10.2 20.4 93.8 20.2 13.3 16.0 22.2 40.4 21.0 7.6 44.3 28.6 15.5 14.6 26.4 19.8 19.8 24.7 18.6 22.9 7.2 7.5 19.8 15.6 22.6 5.5 18.4 15.6 6.3 12.4 40.9 7.3 10.3 15.0 12.0 19.1 13.1 25.1 37.7 84.5 93.5 27.4 23.2 25.9 18.1 28.1 35.0 14.2 SMC4 "CAP-C, hCAP-C, SMC4L1" ENSG00000113810 "Structural maintenance of chromosomes 4" Q9NTJ3 3 160399274-160434954 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 60.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 305.8;Spermatocytes: 339.8;Spermatogonia: 239.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 74.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029449, CAB055509" Approved Supported "Nuclear speckles,Cytosol" NA Yes 25000 "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles, Cytosol" "CAB055509: , HPA029449: AB_10603891" "unprognostic (2.63e-1)" "unprognostic (1.01e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.22e-1)" "unprognostic (1.28e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.54e-2)" "unprognostic (2.18e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (4.20e-5)" "prognostic unfavorable (9.00e-4)" "prognostic unfavorable (8.05e-7)" "unprognostic (3.03e-2)" "unprognostic (4.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.98e-2)" 6.8 6.5 1.0 21.2 2.0 36.3 6.8 1.2 1.7 6.3 1.5 13.2 14.0 7.4 2.3 23.5 4.5 7.6 7.3 0.9 1.9 5.9 7.8 11.8 37.1 1.7 1.4 5.9 7.8 3.8 2.0 16.2 1.6 5.8 14.9 7.7 4.6 5.0 3.6 11.0 15.4 10.1 1.3 14.7 11.8 32.5 1.9 60.6 9.0 6.8 31.6 9.6 4.3 3.2 386.3 72.8 155.0 73.0 31.5 30.9 72.1 181.2 88.8 206.0 176.8 94.4 209.7 236.6 101.9 81.1 140.0 212.5 183.0 95.0 332.4 297.9 113.8 234.7 123.3 33.6 17.3 158.3 182.6 14.6 13.3 114.4 96.5 78.5 94.8 103.2 130.3 272.2 133.9 78.3 183.2 44.4 91.8 106.7 149.3 180.1 238.8 177.3 43.4 54.8 93.7 94.0 141.4 135.1 65.5 76.6 156.9 128.6 84.8 132.2 105.2 119.9 349.8 181.1 192.2 412.0 96.7 166.9 151.9 74.4 6.0 23.6 11.5 8.9 11.4 17.2 18.2 14.3 6.6 15.0 11.4 10.2 10.8 15.3 15.9 11.7 30.3 9.5 1.0 2.0 1.2 1.7 0.9 1.9 1.7 1.4 1.6 1.3 1.9 3.2 24.6 105.8 174.0 3.9 43.7 40.8 18.2 33.1 30.7 14.9 21.5 21.0 41.3 25.8 35.0 35.0 8.4 74.6 54.4 41.4 3.9 20.9 48.6 35.2 27.0 44.8 30.1 305.8 3.5 14.7 138.1 50.7 32.6 36.1 79.1 77.3 38.2 20.4 61.3 0.0 2.9 44.5 24.4 29.7 43.5 28.3 25.1 36.4 17.8 17.8 39.3 9.3 46.4 3.5 30.1 13.5 26.5 48.2 95.9 14.1 25.9 8.6 25.4 25.8 131.5 21.7 73.2 339.8 239.4 58.1 35.7 34.1 58.4 34.6 69.7 19.1 SMCO4 "C11orf75, FN5" ENSG00000166002 "Single-pass membrane protein with coiled-coil domains 4" Q9NRQ5 11 93478472-93543391 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 195.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 211.3;Paneth cells: 165.3;Proximal enterocytes: 200.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 113.7" "Low region specificity" "Detected in all" HPA041120 Uncertain NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "HPA041120: AB_2677309" "unprognostic (7.45e-2)" "unprognostic (1.70e-3)" "unprognostic (2.54e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-1)" "unprognostic (6.47e-2)" "unprognostic (8.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.43e-1)" "unprognostic (5.51e-1)" "unprognostic (4.23e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (5.81e-7)" "unprognostic (1.61e-1)" "unprognostic (3.05e-1)" "unprognostic (1.55e-2)" "unprognostic (5.01e-2)" 21.0 70.4 8.9 30.6 8.2 7.3 23.0 8.2 12.6 17.0 17.3 35.3 45.9 18.9 13.9 23.1 27.9 16.8 53.5 10.2 22.9 66.3 135.1 35.8 31.4 11.9 14.7 25.3 60.0 5.8 48.0 11.4 11.2 55.2 25.7 3.4 195.8 11.5 17.0 24.3 37.6 15.2 11.1 61.8 50.1 43.4 32.4 17.5 71.7 5.9 22.9 12.4 22.8 12.8 8.3 15.3 23.9 5.5 8.0 10.6 15.4 25.2 7.5 10.8 19.9 26.6 33.0 24.6 29.0 22.1 16.8 5.0 24.1 3.5 7.3 68.6 22.2 5.9 32.4 58.0 7.4 24.4 26.1 15.0 13.2 5.0 3.8 13.6 16.7 81.5 13.8 113.7 3.3 13.9 24.4 50.2 25.0 62.6 23.9 42.8 12.0 11.2 21.5 19.8 4.2 18.5 19.6 26.3 2.1 30.2 10.4 33.7 10.9 9.7 40.6 33.4 20.8 4.6 0.7 19.7 7.6 40.9 4.9 40.2 263.5 6.9 4.1 316.4 18.4 25.0 26.9 8.0 150.3 26.9 3.7 3.2 61.4 32.0 296.3 155.5 11.7 91.5 8.9 8.2 8.2 12.6 10.2 22.9 11.9 14.7 11.2 11.1 32.4 12.8 26.0 25.6 18.4 0.3 11.5 32.8 33.4 17.4 6.2 2.1 62.0 50.5 36.7 70.1 17.2 49.7 0.0 6.6 27.7 105.1 211.3 43.2 123.5 14.3 2.9 24.9 44.9 6.1 4.8 70.2 9.0 19.0 27.5 16.1 2.5 21.3 15.7 103.9 140.4 3.3 10.6 116.4 6.1 91.3 80.3 146.8 12.8 87.7 30.2 13.1 123.3 6.4 11.3 0.5 4.4 31.1 165.3 10.5 15.0 92.8 200.0 64.8 9.6 1.3 6.6 4.2 14.1 11.2 46.6 16.6 21.3 4.8 15.0 6.4 58.7 47.3 SMIM1 Vel ENSG00000235169 "Small integral membrane protein 1 (Vel blood group)" B2RUZ4 1 3772749-3775982 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 40.3;testis: 42.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 84.1;Erythroid cells: 404.4;Granulosa cells: 81.5;Proximal tubular cells: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "eosinophil: 48.5" "Lineage enriched" "Detected in many" 12 "granulocytes: 48.5" "Group enriched" "Detected in many" 4 "HEL: 68.0;Hep G2: 32.5;K-562: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA069088 Enhanced NA NA 340000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA069088: AB_2686080" "unprognostic (9.50e-3)" "unprognostic (7.19e-4)" "unprognostic (5.40e-2)" "unprognostic (2.10e-2)" "unprognostic (2.50e-3)" "unprognostic (3.25e-1)" "unprognostic (2.63e-3)" "unprognostic (2.13e-2)" "unprognostic (2.31e-2)" "unprognostic (9.85e-2)" "unprognostic (2.90e-1)" "unprognostic (1.87e-1)" "unprognostic (2.25e-2)" "unprognostic (7.10e-2)" "unprognostic (2.91e-2)" "unprognostic (5.56e-2)" "unprognostic (1.32e-2)" 2.6 2.7 1.8 0.4 2.6 32.1 3.2 3.8 3.0 5.8 6.2 2.9 0.7 2.8 1.1 1.4 3.4 1.3 40.3 1.4 3.9 16.9 13.1 3.7 1.0 8.7 5.3 8.7 9.4 4.3 16.0 2.1 9.0 6.9 0.1 0.4 17.3 5.5 1.1 2.1 2.1 0.2 5.5 4.0 6.6 42.2 3.6 0.4 9.3 0.2 0.5 3.4 3.6 6.2 0.3 1.4 1.4 3.0 0.0 0.0 5.0 0.9 1.2 0.0 0.0 3.5 3.9 0.1 6.3 0.0 0.2 1.3 0.4 1.5 0.0 6.1 3.6 68.0 0.0 32.5 2.4 0.0 1.2 2.1 0.8 0.3 0.5 2.9 0.0 0.3 33.9 1.2 0.0 7.8 0.0 2.1 0.3 3.4 6.0 0.0 0.0 9.9 3.8 1.0 1.6 6.3 0.2 6.8 4.8 0.5 7.0 3.7 0.4 0.0 0.8 0.0 0.0 2.8 0.8 0.2 0.0 0.0 0.2 4.4 2.0 48.5 1.1 1.0 0.4 2.5 1.6 0.6 0.6 3.7 4.0 1.9 3.2 0.2 0.4 0.6 1.2 2.2 1.8 2.6 3.8 3.0 1.4 3.9 8.7 5.3 9.0 5.5 3.6 6.2 1.1 6.4 20.1 0.7 5.9 1.7 13.1 4.4 10.2 0.4 31.1 35.9 57.0 8.6 8.1 16.5 0.0 23.4 1.4 1.6 84.1 17.2 10.8 3.7 1.2 3.9 5.4 404.4 0.1 14.5 18.8 10.1 6.6 3.5 1.3 81.5 3.9 50.2 10.4 1.7 0.1 3.9 8.2 8.9 1.0 27.8 9.9 8.5 42.7 0.0 4.3 47.0 2.1 0.0 1.6 13.7 1.7 9.8 11.1 10.2 1.9 247.9 2.2 1.5 0.0 3.6 4.3 8.7 20.4 1.7 1.1 6.7 4.6 3.0 4.3 9.1 SMIM22 CASIMO1 ENSG00000267795 "Small integral membrane protein 22" K7EJ46 16 4788397-4796491 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.6;pancreas: 154.3;salivary gland: 147.2;stomach 1: 201.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2005.0;Intestinal goblet cells: 1223.5;Paneth cells: 1462.9;Proximal enterocytes: 1685.8;Respiratory ciliated cells: 686.7;Undifferentiated cells: 775.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CAPAN-2: 261.7;OE19: 247.3;RT4: 89.8;SCLC-21H: 70.7;SK-BR-3: 201.2" "Low region specificity" "Detected in many" HPA077331 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA077331: AB_2686834" "unprognostic (6.55e-2)" "unprognostic (4.12e-2)" "unprognostic (4.84e-2)" "unprognostic (3.69e-3)" "unprognostic (7.82e-2)" "unprognostic (3.84e-2)" "unprognostic (4.63e-2)" "unprognostic (2.67e-2)" "unprognostic (6.20e-2)" "unprognostic (3.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.60e-1)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (1.73e-3)" 1.2 0.3 0.1 14.6 1.2 3.5 48.2 4.6 2.0 45.4 0.0 193.6 129.6 8.9 50.4 10.3 77.3 33.3 0.5 0.5 0.4 42.0 1.4 24.1 0.6 2.6 0.9 0.5 154.3 0.1 48.9 2.0 2.1 42.6 122.7 1.5 147.2 36.3 0.2 10.4 128.4 6.3 0.8 0.2 201.7 33.8 2.6 0.2 1.1 0.0 2.7 46.1 6.5 3.1 0.2 0.0 0.1 0.6 0.0 0.0 1.9 0.3 0.1 0.1 0.1 0.6 261.7 0.3 7.3 0.0 0.3 1.3 0.1 0.0 0.1 0.4 1.9 0.1 5.8 0.9 0.1 0.7 0.3 0.2 1.4 0.0 0.0 0.2 0.1 0.4 0.0 0.6 0.0 1.9 0.1 0.6 0.8 247.3 0.0 0.8 0.3 23.6 1.5 89.8 70.7 0.8 0.5 201.2 0.0 0.5 15.2 0.0 0.0 0.6 0.8 1.1 0.1 0.2 0.6 0.9 0.0 0.7 0.6 1.2 0.3 0.4 0.3 0.1 0.1 0.1 0.3 0.1 0.0 0.4 0.3 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.1 1.2 4.6 2.0 0.5 0.4 2.6 0.9 2.1 0.8 2.6 3.1 1.4 48.1 117.7 0.0 5.8 2.2 22.7 92.7 0.0 4.2 363.3 267.5 0.5 183.0 154.9 250.1 0.0 3.9 3.0 2005.0 25.4 259.8 40.1 430.4 26.5 4.4 470.3 0.0 0.5 381.9 0.4 4.7 438.8 258.3 18.4 0.1 0.4 0.2 0.4 1.7 0.3 1223.5 152.5 0.0 0.8 107.3 0.6 4.2 23.2 0.0 5.3 0.6 0.0 0.0 1.3 539.9 1462.9 1.2 1.0 29.5 1685.8 99.4 686.7 4.2 0.0 0.0 15.9 38.6 0.6 2.3 2.3 3.7 6.6 0.2 775.6 148.6 SMIM29 "C6orf1, LBH, MGC57858" ENSG00000186577 "Small integral membrane protein 29" Q86T20 6 34246381-34249108 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 175.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 72.4;Ductal cells: 50.9;Hofbauer cells: 104.0;monocytes: 44.5;Proximal tubular cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 412.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA037659, HPA037660" Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "HPA037659: AB_2675591, HPA037660: AB_10671881" "unprognostic (2.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-2)" "unprognostic (2.10e-1)" "unprognostic (3.23e-1)" "unprognostic (1.93e-3)" "unprognostic (1.36e-2)" "unprognostic (2.62e-1)" "unprognostic (4.12e-2)" "prognostic favorable (7.98e-4)" "unprognostic (9.32e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (3.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.16e-2)" "unprognostic (3.66e-1)" 19.4 29.7 133.7 14.4 129.9 14.7 19.5 131.5 175.9 26.5 98.3 24.2 8.4 19.8 34.5 26.9 17.0 17.1 29.8 131.3 135.5 22.5 18.7 27.8 21.3 138.0 136.0 16.4 15.4 18.6 33.4 13.2 142.4 22.8 6.1 16.1 16.2 16.3 24.5 48.8 17.9 12.2 133.5 30.8 16.9 11.7 139.1 14.6 25.7 23.5 15.5 24.0 26.0 128.0 25.1 31.1 6.2 33.3 79.2 62.2 6.7 24.6 58.4 27.4 34.4 7.6 12.3 14.1 19.8 28.6 56.6 15.6 12.7 31.3 8.9 36.0 17.3 10.5 6.1 19.9 45.4 12.0 62.0 33.7 28.4 38.5 37.6 38.4 40.9 11.6 13.5 81.8 64.0 17.9 13.5 24.2 1.9 42.8 21.5 5.5 3.8 25.1 33.1 32.4 26.0 12.1 2.6 23.8 70.9 5.3 14.1 19.1 26.4 62.1 14.4 65.1 21.6 42.9 66.1 4.7 35.4 25.7 82.9 99.1 83.8 412.8 78.7 62.7 52.6 133.3 62.4 69.1 59.7 126.4 41.8 61.8 231.6 57.1 48.3 50.1 90.3 64.0 133.7 129.9 131.5 175.9 131.3 135.5 138.0 136.0 142.4 133.5 139.1 128.0 18.1 9.6 13.6 0.0 5.6 0.0 0.0 0.0 0.0 0.0 28.5 20.8 0.0 0.0 6.8 31.3 0.0 37.8 13.6 0.0 72.4 50.9 0.0 9.9 8.6 15.5 0.0 0.0 0.0 24.0 11.8 8.0 0.0 15.0 12.6 10.8 0.0 0.0 104.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 44.5 0.0 0.0 0.0 0.0 25.3 0.0 0.0 1.9 0.0 0.0 43.8 10.2 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 35.4 9.4 17.8 0.0 0.0 SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390440-6394998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 131.3;Late spermatids: 200.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 139.1;fHDF/TERT166: 144.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (6.99e-2)" "unprognostic (2.28e-3)" "prognostic unfavorable (7.72e-5)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (4.90e-2)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.47e-4)" "unprognostic (4.35e-2)" "prognostic favorable (4.57e-6)" "unprognostic (4.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" 21.8 36.5 38.8 13.9 44.7 7.3 20.1 45.1 43.0 21.2 33.9 25.3 16.8 20.9 14.4 20.6 14.6 21.5 55.8 39.1 43.0 73.7 95.3 31.3 14.6 42.7 42.6 17.9 32.8 34.2 41.9 21.6 43.3 29.4 14.9 8.5 29.0 20.0 37.9 37.9 23.8 17.6 40.9 21.1 25.4 14.0 47.5 17.8 34.0 29.4 11.0 23.6 21.0 46.8 16.4 13.1 10.1 26.5 139.1 72.2 17.1 60.4 95.0 27.7 33.0 22.0 11.9 4.7 27.4 144.0 59.3 7.4 8.4 12.7 13.0 21.0 9.6 5.1 19.5 6.0 62.3 3.7 37.4 96.0 23.4 25.9 17.7 100.9 61.6 1.7 9.1 30.5 58.9 17.0 0.1 6.5 3.9 23.2 22.3 1.2 5.5 7.0 23.9 6.2 17.0 9.7 27.6 19.5 38.5 12.9 7.3 7.0 53.9 103.0 10.9 59.1 15.4 37.6 44.0 3.5 93.7 10.8 47.1 1.9 2.5 3.4 6.4 2.1 5.0 1.5 5.5 5.0 1.3 3.1 10.0 10.1 2.5 6.6 0.6 1.7 4.7 3.2 38.8 44.7 45.1 43.0 39.1 43.0 42.7 42.6 43.3 40.9 47.5 46.8 14.1 25.6 14.4 10.7 12.2 7.9 22.8 15.3 6.8 12.6 13.7 9.0 37.7 24.3 12.8 25.8 25.0 38.8 11.5 131.3 11.7 53.4 50.0 6.2 13.0 18.6 23.8 9.9 5.8 38.2 14.4 31.4 15.8 21.0 10.8 9.4 26.7 88.5 34.1 20.2 5.5 20.3 24.4 15.5 6.2 200.7 11.5 15.8 55.2 4.7 7.8 16.4 36.0 6.6 15.5 24.7 83.1 13.5 23.1 26.0 51.7 75.1 2.4 5.2 0.0 8.9 17.1 1.4 3.1 7.5 8.0 34.3 23.3 10.2 18.0 15.4 SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 61.5;lymphoid tissue: 52.0" "Cell type enhanced" "Detected in many" "dendritic cells: 77.1;Gastric mucus-secreting cells: 70.8;Horizontal cells: 301.2;Proximal enterocytes: 115.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 8.0;basal ganglia: 29.7;cerebral cortex: 24.9;hippocampal formation: 25.4" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 138.9" "Lineage enriched" "Detected in many" 7 "dendritic cells: 138.9" "Cell line enhanced" "Detected in some" "HMC-1: 9.7;MOLT-4: 14.7;RPMI-8226: 12.4;SCLC-21H: 13.4" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 67.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" 6.8 2.1 8.0 3.6 29.7 1.8 2.8 1.8 24.9 2.7 0.1 13.8 61.5 1.4 0.1 2.1 3.8 9.0 1.5 25.4 0.5 4.0 7.4 2.5 4.2 0.0 0.2 4.8 2.6 0.1 16.5 0.2 0.6 4.6 6.9 6.5 3.0 0.3 2.4 13.6 57.7 0.7 0.5 3.4 23.2 8.6 5.1 52.0 2.7 0.0 1.9 1.7 2.5 2.3 0.3 0.8 0.4 0.1 0.0 0.0 5.5 0.4 0.0 0.4 0.1 3.1 1.0 0.4 0.6 0.3 0.2 1.2 0.0 0.0 0.1 0.3 0.7 0.1 2.7 0.3 0.0 0.0 9.7 0.0 0.0 0.0 0.2 0.5 0.0 0.9 0.9 0.3 0.3 0.2 14.7 2.8 0.6 4.9 0.1 0.7 0.2 12.4 0.0 0.1 13.4 2.7 0.4 1.6 0.7 0.2 1.1 0.9 0.0 0.4 0.8 1.4 0.1 2.3 1.2 0.3 0.2 0.9 0.2 4.4 0.0 20.7 2.3 0.1 0.3 1.7 0.2 0.6 0.1 0.9 0.6 0.3 0.1 0.1 0.0 138.9 1.9 1.2 8.0 29.7 1.8 24.9 25.4 0.5 0.0 0.2 0.6 0.5 5.1 2.3 0.3 3.2 1.1 1.0 2.6 0.1 1.5 0.6 0.0 50.8 1.8 0.6 2.9 15.7 1.5 0.0 0.0 0.0 77.1 44.7 0.0 1.3 8.5 3.0 0.3 0.6 25.8 0.4 33.8 0.9 0.1 5.2 70.8 0.5 0.0 0.2 0.7 9.4 0.3 301.2 20.4 34.7 2.0 1.0 0.5 18.6 15.2 2.9 0.0 1.9 0.6 0.9 1.0 10.6 1.7 1.6 39.9 45.9 2.5 3.6 115.1 0.0 14.6 3.9 0.0 0.2 0.3 10.0 2.1 0.1 1.0 0.0 6.2 0.2 21.6 5.4 SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.3;Distal enterocytes: 291.5;Paneth cells: 157.5;Proximal enterocytes: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 80.9" "Lineage enriched" "Detected in many" 11 "granulocytes: 80.9" "Cell line enhanced" "Detected in many" "ASC diff: 44.2;hTCEpi: 36.9;OE19: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" No No 26000000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 15.0 23.3 4.6 18.7 5.1 22.9 23.7 8.2 9.4 72.8 8.9 60.7 45.5 13.3 6.5 13.6 7.9 17.2 5.6 5.3 5.7 47.4 80.0 14.1 21.4 5.9 5.4 9.1 20.8 32.4 7.5 44.0 5.9 21.8 65.7 6.0 13.7 16.6 39.8 64.5 77.3 8.5 5.7 27.0 30.5 2.9 5.4 5.1 9.1 55.8 16.2 35.5 30.9 7.7 0.3 2.6 6.1 2.8 44.2 19.9 19.5 10.4 27.8 3.1 6.6 3.3 2.7 0.0 1.4 6.6 8.2 4.9 1.7 5.3 2.6 0.0 5.4 2.5 9.8 9.0 28.3 0.0 0.1 24.4 36.9 3.0 5.3 12.0 5.5 0.0 3.8 0.0 12.7 9.3 0.0 0.2 1.1 58.8 8.0 0.0 10.8 0.4 15.1 4.2 4.4 0.1 1.5 18.5 27.9 3.9 3.1 1.4 11.0 5.9 3.5 0.6 6.8 0.0 0.0 0.0 8.7 4.9 13.7 80.9 4.0 1.1 0.0 4.3 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 7.5 0.0 0.0 1.4 4.6 5.1 8.2 9.4 5.3 5.7 5.9 5.4 5.9 5.7 5.4 7.7 11.8 3.2 17.8 5.2 2.4 53.7 24.5 13.7 15.9 3.0 12.2 6.6 4.0 25.8 9.7 5.5 4.2 156.3 0.4 291.5 56.7 24.6 0.2 4.2 12.6 7.1 48.7 5.7 7.4 25.7 40.4 46.3 34.7 5.2 10.1 0.8 18.9 77.8 62.7 3.3 10.5 61.7 59.0 126.3 10.0 1.2 15.5 33.4 35.6 11.2 9.9 11.5 2.1 11.1 11.0 19.5 157.5 14.3 0.9 16.7 383.1 129.3 7.5 6.2 13.1 12.8 9.9 1.1 3.7 15.5 76.0 115.1 2.0 11.4 38.9 16.6 SMU1 "BWD, FLJ10805, fSAP57, SMU-1" ENSG00000122692 "SMU1 DNA replication regulator and spliceosomal factor" Q2TAY7 9 33041765-33076674 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019708 Supported Approved Vesicles NA NA 25000 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019708: AB_1857300" "unprognostic (2.20e-2)" "prognostic favorable (2.66e-4)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (1.80e-2)" "unprognostic (8.44e-2)" "unprognostic (2.59e-3)" "unprognostic (5.06e-2)" "unprognostic (3.04e-2)" "prognostic favorable (1.25e-4)" "unprognostic (4.98e-3)" "unprognostic (3.15e-1)" "prognostic favorable (1.67e-5)" "unprognostic (1.09e-2)" "unprognostic (7.04e-2)" "unprognostic (8.71e-2)" "unprognostic (5.96e-2)" 11.5 11.3 11.2 10.6 13.0 16.0 11.9 13.9 12.1 11.4 8.6 10.9 8.6 13.1 11.8 10.6 11.4 8.6 10.3 10.7 11.5 11.2 12.9 10.0 12.8 12.4 11.9 14.7 8.2 15.8 8.1 8.4 12.4 11.9 10.9 12.6 9.3 11.5 14.4 12.8 9.4 13.2 12.6 12.1 9.1 8.5 11.7 14.1 11.2 13.0 15.2 11.5 9.9 16.6 26.3 20.4 24.0 20.9 25.4 19.3 18.7 20.1 18.1 26.9 26.5 20.8 10.7 33.0 14.4 25.1 14.6 15.7 31.1 24.1 29.7 38.1 14.9 24.8 33.4 24.5 22.1 43.5 22.4 20.4 27.0 24.9 17.6 20.1 22.9 22.7 23.4 20.5 22.7 12.1 34.2 46.3 33.1 19.6 21.4 28.8 19.9 17.9 20.5 19.4 20.3 17.7 27.2 19.4 13.1 18.6 18.7 15.7 24.6 17.2 19.1 25.2 23.8 9.1 18.1 38.0 19.2 20.2 12.5 23.4 13.9 11.5 12.4 15.4 13.3 12.9 14.0 11.6 15.8 11.7 13.9 14.3 8.1 12.4 17.9 20.0 12.6 10.8 11.2 13.0 13.9 12.1 10.7 11.5 12.4 11.9 12.4 12.6 11.7 16.6 45.5 25.6 31.4 17.9 48.0 53.7 45.7 41.0 43.3 29.5 23.8 22.4 30.6 30.0 39.9 20.2 37.5 34.9 72.7 19.1 21.5 32.3 29.6 41.6 42.8 38.2 28.1 24.4 23.4 24.3 36.3 37.7 17.9 47.3 39.2 32.1 21.4 29.4 30.8 23.5 25.3 19.5 44.7 29.2 40.8 8.7 32.3 40.2 23.2 14.0 39.7 34.8 32.0 21.6 28.3 27.9 20.1 25.9 28.3 33.3 18.1 31.7 44.1 39.3 19.7 53.9 44.7 41.4 30.5 36.3 57.5 57.7 43.7 37.0 23.5 35.5 SNCA "NACP, PARK1, PARK4, PD1" ENSG00000145335 "Synuclein alpha" P37840 4 89700345-89838315 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Alzheimer disease, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 273.6;brain: 128.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 1225.0;Excitatory neurons: 251.5;Melanocytes: 352.2;Oligodendrocytes: 195.4" "Cancer enriched" "Detected in many" 8 "melanoma: 37.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 102.9" "Group enriched" "Detected in all" 4 "dendritic cells: 102.9;granulocytes: 51.5;monocytes: 66.9" "Cell line enhanced" "Detected in many" "HEL: 221.5;HUVEC TERT2: 269.8;RT4: 137.3;SK-MEL-30: 271.6;TIME: 311.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005459, CAB010877" Enhanced "Intracellular and membrane" NA NA 28000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010877: AB_261518, HPA005459: AB_2667324" "unprognostic (4.80e-2)" "unprognostic (1.52e-1)" "unprognostic (8.13e-2)" "unprognostic (1.05e-3)" "unprognostic (2.65e-2)" "unprognostic (1.54e-2)" "unprognostic (1.78e-2)" "unprognostic (3.44e-2)" "unprognostic (1.73e-2)" "unprognostic (3.85e-3)" "unprognostic (1.01e-3)" "unprognostic (2.09e-2)" "unprognostic (1.57e-1)" "unprognostic (2.51e-3)" "unprognostic (1.68e-1)" "unprognostic (3.93e-4)" "unprognostic (7.48e-3)" 16.0 9.9 91.5 10.0 112.2 273.6 7.8 47.2 128.2 26.1 16.1 28.5 3.3 34.3 3.4 8.5 11.2 5.4 20.9 115.2 69.1 12.4 2.9 16.6 2.2 97.5 88.3 29.3 2.2 1.1 28.7 28.3 89.9 17.3 6.9 20.3 15.9 9.7 1.2 16.4 8.6 33.3 36.0 15.2 6.4 3.2 76.2 5.3 10.2 8.5 4.8 9.3 23.2 107.0 0.5 1.0 40.1 0.0 0.7 0.0 0.6 0.4 44.5 1.6 3.0 0.0 0.0 0.2 12.0 0.0 0.0 9.3 53.6 97.7 1.5 0.0 22.6 221.5 115.4 0.5 84.2 0.0 1.4 2.1 38.2 0.0 109.5 117.3 269.8 2.2 2.0 0.6 0.2 0.0 2.1 0.3 10.6 0.2 4.8 0.0 15.8 0.0 0.3 137.3 23.2 15.6 0.2 0.3 271.6 29.0 0.0 0.4 311.4 1.3 8.0 0.1 0.8 0.2 0.2 0.1 8.8 0.2 87.4 51.5 66.9 0.1 0.3 27.7 0.1 4.2 1.9 0.3 84.6 1.7 1.0 0.5 11.1 17.3 8.2 102.9 0.0 63.7 91.5 112.2 47.2 128.2 115.2 69.1 97.5 88.3 89.9 36.0 76.2 107.0 1.8 0.0 0.6 40.1 2.6 76.6 16.3 173.4 101.3 10.4 0.9 14.4 13.4 0.0 21.5 11.0 0.0 10.1 10.1 0.1 1.9 0.0 0.6 0.3 1.1 19.4 1.8 1225.0 251.5 0.2 1.9 32.7 0.0 0.3 0.0 23.9 7.5 0.8 62.3 10.1 53.8 0.0 44.7 17.2 64.2 1.5 2.1 100.7 352.2 76.8 24.4 19.4 4.1 95.5 195.4 0.2 0.0 0.0 0.5 11.3 0.0 2.0 6.6 7.4 13.1 0.5 5.3 19.6 16.9 4.5 22.6 3.4 3.8 43.6 0.0 3.4 SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 55.0;breast: 14.2;skin 1: 32.2" "Group enriched" "Detected in some" 22 "Breast glandular cells: 367.0;Breast myoepithelial cells: 324.9" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "basophil: 2.8" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.8" "Cell line enriched" "Detected in some" 13 "Hep G2: 59.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA052824: AB_2681964" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-1)" "unprognostic (4.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (4.30e-7)" "unprognostic (1.83e-3)" "unprognostic (8.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.33e-2)" 1.3 0.9 6.7 0.2 14.1 0.5 14.2 21.2 8.5 0.7 0.2 3.3 0.9 0.7 0.5 1.0 1.2 0.0 0.8 11.9 23.5 1.3 7.4 0.8 0.6 37.8 14.8 0.7 1.7 0.3 1.6 0.2 28.3 1.5 0.3 0.6 4.7 0.1 1.0 32.2 1.7 0.1 38.2 1.1 0.8 8.1 14.2 0.1 0.6 0.0 0.0 0.9 0.8 55.0 0.9 0.0 0.3 1.4 1.0 1.6 2.4 0.3 0.0 0.3 0.7 0.0 0.2 0.0 0.7 0.1 0.5 0.5 0.0 0.0 0.0 0.6 2.1 0.5 0.4 59.6 0.8 0.1 1.7 0.0 1.3 0.4 0.8 0.7 1.6 0.6 0.1 0.2 0.2 0.2 0.2 0.5 0.0 0.0 2.2 0.4 0.6 0.4 0.1 0.9 0.2 0.8 0.4 0.0 2.2 1.0 0.1 2.6 0.9 0.2 0.8 0.8 0.8 3.8 4.7 0.2 0.1 1.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 14.1 21.2 8.5 11.9 23.5 37.8 14.8 28.3 38.2 14.2 55.0 3.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 367.0 324.9 0.0 0.0 0.0 1.8 0.0 0.1 10.1 0.0 5.9 0.5 0.0 3.8 0.4 6.3 0.0 0.0 0.0 0.8 0.1 2.9 0.0 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 2.3 0.9 0.0 0.0 SNW1 "Bx42, FUN20, NCoA-62, Prp45, PRPF45, SKIIP, SKIP, SKIP1" ENSG00000100603 "SNW domain containing 1" Q13573 14 77717599-77761207 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 300.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002457, CAB009931, HPA017370" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB009931: AB_2302187, HPA002457: AB_1080047, HPA017370: AB_1857339" "unprognostic (1.24e-3)" "unprognostic (2.02e-1)" "unprognostic (2.40e-1)" "unprognostic (6.43e-2)" "unprognostic (3.04e-1)" "unprognostic (4.27e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.07e-1)" "unprognostic (8.09e-3)" "unprognostic (2.88e-2)" "unprognostic (3.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.67e-1)" "unprognostic (2.47e-1)" "unprognostic (1.55e-1)" "unprognostic (4.45e-3)" "unprognostic (1.22e-2)" 47.1 33.3 27.6 33.6 29.5 91.2 42.7 30.6 35.9 39.2 29.1 38.4 32.6 39.0 28.4 38.4 38.3 26.7 39.5 27.0 29.0 38.7 33.6 37.1 46.2 29.5 28.6 41.4 38.6 31.3 30.3 33.0 29.8 32.2 32.1 43.3 34.0 21.9 64.8 50.7 38.5 30.9 28.6 44.6 36.6 48.5 28.4 49.0 33.9 35.9 41.9 38.8 38.0 32.9 91.0 66.6 67.0 70.8 54.5 60.6 76.5 61.3 54.6 66.8 61.2 66.0 81.0 88.3 54.5 46.1 50.8 88.2 81.8 58.9 90.3 71.1 63.5 71.8 59.1 66.7 77.7 50.5 81.0 46.8 76.1 60.0 82.8 71.5 65.8 83.7 103.9 64.7 51.9 93.1 90.7 85.4 74.2 103.1 87.8 97.3 85.5 61.7 61.4 82.6 71.2 76.5 84.7 73.6 87.3 68.1 106.6 95.5 69.9 71.6 81.7 64.9 73.9 62.9 95.5 98.7 65.5 79.8 80.9 94.5 71.0 95.6 57.5 76.9 65.5 59.2 64.5 65.9 72.6 67.0 67.6 63.9 67.8 94.5 92.1 43.2 94.5 76.1 27.6 29.5 30.6 35.9 27.0 29.0 29.5 28.6 29.8 28.6 28.4 32.9 86.5 93.0 49.3 13.1 64.2 56.5 80.4 89.1 33.6 56.0 40.1 50.0 49.9 47.1 77.9 53.3 35.5 79.4 75.4 38.0 76.3 79.0 43.5 97.2 81.3 69.9 43.6 85.0 17.9 70.1 100.1 64.9 26.5 80.5 92.3 61.5 55.6 33.7 76.4 38.7 18.6 50.8 54.9 53.6 52.0 24.0 77.9 70.7 39.2 30.0 95.6 66.7 65.9 15.6 31.9 71.3 43.8 74.1 46.3 48.9 48.8 57.3 88.1 72.2 65.7 60.9 89.5 300.5 140.7 39.7 54.3 109.0 76.8 54.4 47.9 70.9 SOAT1 "ACAT, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 165.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum" "CAB009533: AB_633499, HPA047171: AB_2679967" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.81e-3)" "unprognostic (7.81e-3)" "unprognostic (3.29e-1)" "unprognostic (9.00e-2)" "unprognostic (9.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.45e-3)" "unprognostic (7.02e-3)" "unprognostic (4.67e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-2)" "unprognostic (1.82e-1)" 14.6 165.3 4.2 18.1 5.7 17.5 8.2 5.5 6.6 13.7 9.0 13.0 12.2 11.7 6.6 4.8 17.9 20.5 5.4 3.3 6.8 12.7 14.1 20.9 15.1 10.1 6.1 10.7 27.0 13.4 6.3 19.1 8.0 27.7 14.8 10.3 39.4 9.3 4.0 5.7 12.7 16.5 8.0 15.1 16.3 11.0 6.7 8.1 9.2 3.7 13.1 11.7 4.5 12.8 74.6 34.1 27.7 41.0 104.7 56.6 147.3 35.1 61.7 76.2 88.3 35.2 82.6 42.0 53.9 64.4 92.6 26.8 88.6 20.9 81.8 48.0 18.2 19.5 26.7 36.9 42.9 33.5 7.5 45.4 13.3 89.2 75.8 32.1 33.3 50.5 42.7 21.0 120.0 15.9 35.9 10.8 13.4 11.8 11.2 44.4 35.8 24.4 66.1 45.9 8.4 21.5 54.3 22.9 20.1 32.3 24.0 22.8 31.9 89.8 43.1 99.5 78.2 29.4 115.3 35.5 35.7 17.9 170.6 55.4 53.4 1.6 26.4 34.2 25.0 12.9 24.0 24.8 48.9 10.4 23.0 23.3 39.3 37.9 23.7 8.8 33.2 32.5 4.2 5.7 5.5 6.6 3.3 6.8 10.1 6.1 8.0 8.0 6.7 12.8 14.9 22.4 33.4 11.4 16.0 9.9 10.1 11.3 8.0 7.3 7.2 4.6 8.5 30.0 14.5 20.2 14.6 17.6 21.2 16.0 1.9 42.5 29.5 34.9 32.8 16.0 59.9 9.0 12.1 25.0 51.6 21.3 18.3 34.5 14.0 9.2 15.4 24.2 70.3 6.7 15.0 25.5 22.4 77.4 41.9 14.5 32.6 74.9 23.2 29.0 55.4 7.6 19.6 10.6 7.3 20.3 13.3 25.9 17.7 26.7 8.7 14.9 46.2 14.5 26.3 9.2 13.5 6.8 9.7 5.0 5.3 8.8 24.8 44.3 15.5 8.5 SOCS2 "CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2" ENSG00000120833 "Suppressor of cytokine signaling 2" O14508 12 93569814-93583487 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 203.6;Hepatic stellate cells: 134.6" "Cancer enhanced" "Detected in all" "prostate cancer: 16.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 177.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 177.8" "Cell line enhanced" "Detected in many" "CACO-2: 192.0;K-562: 145.6;REH: 336.6;THP-1: 142.3" "Low region specificity" "Detected in all" CAB010356 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "CAB010356: AB_2239660" "unprognostic (4.16e-2)" "unprognostic (2.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" "prognostic favorable (1.09e-6)" "unprognostic (1.07e-1)" "unprognostic (1.49e-1)" "unprognostic (5.35e-3)" "prognostic favorable (8.17e-7)" "unprognostic (1.71e-1)" "unprognostic (1.67e-3)" "unprognostic (2.35e-2)" "unprognostic (1.51e-1)" "unprognostic (7.40e-2)" "unprognostic (9.09e-2)" 71.5 34.8 7.8 10.4 12.0 11.5 68.0 7.2 8.5 92.6 23.1 40.5 11.7 91.8 42.0 16.5 42.4 20.7 28.6 9.8 9.2 42.8 59.1 61.9 9.2 8.1 10.9 19.2 13.8 64.5 55.3 36.5 8.8 81.4 17.0 4.8 9.5 45.4 9.5 9.4 17.3 89.5 6.6 8.5 30.8 8.7 10.4 21.4 32.8 6.1 9.1 32.1 50.4 7.8 3.5 4.9 16.8 15.2 9.1 16.6 19.8 20.8 77.0 15.2 6.6 192.0 7.8 1.0 0.7 19.3 4.1 39.8 88.6 5.9 17.3 69.0 2.5 13.9 1.2 2.7 13.8 4.2 28.5 28.3 4.9 16.7 22.7 1.6 2.1 8.7 145.6 3.1 2.4 1.8 0.8 6.8 47.4 3.2 7.4 336.6 0.3 3.6 4.1 7.4 28.8 34.2 7.3 11.5 57.5 16.0 0.2 142.3 2.3 47.2 0.7 0.3 11.7 2.0 1.1 1.4 0.9 12.0 28.8 177.8 0.2 7.7 25.4 0.5 34.2 0.4 31.2 23.3 0.2 4.3 30.6 18.4 1.1 26.8 0.4 2.0 19.8 14.4 7.8 12.0 7.2 8.5 9.8 9.2 8.1 10.9 8.8 6.6 10.4 7.8 203.6 9.6 78.7 1.0 1.4 18.0 46.0 3.2 1.2 8.2 30.5 16.9 6.5 0.0 24.3 22.0 4.2 36.3 15.5 20.8 62.6 13.7 9.8 10.5 94.9 100.5 8.3 33.2 10.9 37.4 6.7 34.6 7.1 20.2 24.1 9.9 134.6 11.6 14.2 69.0 12.3 13.3 4.1 8.9 20.7 20.3 91.6 6.0 17.8 8.4 108.4 1.5 18.6 1.0 1.3 8.8 21.2 101.2 6.4 95.2 20.0 27.5 5.4 1.2 78.9 15.8 32.9 9.9 10.5 1.8 10.5 35.0 15.7 12.7 15.7 30.1 SOD3 EC-SOD ENSG00000109610 "Superoxide dismutase 3" P08294 4 24789912-24800842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Antioxidant, Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 436.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 498.5;Leydig cells: 424.1;Peritubular cells: 365.6;Smooth muscle cells: 428.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.2;BJ: 38.1;PC-3: 55.1;RPTEC TERT1: 231.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042110 Supported "Secreted to blood" NA NA 50400000 510000000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "HPA042110: AB_2677850" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (8.80e-2)" "unprognostic (3.32e-2)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (4.98e-2)" "unprognostic (3.68e-1)" "unprognostic (2.39e-1)" "unprognostic (3.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-2)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.45e-2)" 221.4 20.4 14.3 26.1 20.9 0.0 134.2 15.8 23.8 226.5 436.1 122.7 18.2 151.6 10.4 62.1 177.6 22.4 150.1 47.1 14.1 124.1 16.5 155.0 10.6 22.9 23.4 59.7 86.7 2.6 19.8 39.8 17.5 131.3 13.4 1.9 70.9 23.4 22.0 91.9 65.2 37.1 16.4 24.8 102.1 74.1 19.0 5.8 176.6 22.9 7.0 178.3 170.4 13.6 0.0 0.0 0.0 0.0 66.2 17.3 2.0 38.1 16.7 2.3 1.4 0.5 0.0 0.0 11.8 8.0 0.1 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.0 16.8 0.0 15.8 0.0 17.9 0.1 0.0 1.1 0.0 0.0 0.1 0.3 1.1 8.0 0.0 55.1 0.0 0.0 0.6 231.3 0.8 0.2 0.2 0.0 1.2 0.0 2.1 32.8 0.0 0.0 8.7 1.0 1.6 0.4 0.1 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 20.9 15.8 23.8 47.1 14.1 22.9 23.4 17.5 16.4 19.0 13.6 46.1 12.8 18.1 7.2 1.0 90.8 65.5 0.6 10.2 0.4 21.7 22.1 23.0 144.4 7.6 90.1 0.0 211.4 1.8 25.6 15.6 63.6 18.7 81.9 45.8 21.0 34.6 0.0 0.1 1.8 17.0 498.5 5.1 80.3 0.0 0.1 15.4 0.2 17.3 0.0 0.1 51.9 0.0 0.3 115.5 33.9 424.1 3.2 80.0 3.7 0.0 20.7 0.0 0.5 0.7 3.5 89.3 365.6 1.1 80.4 0.0 142.7 0.1 1.4 197.2 6.5 428.9 73.2 4.4 6.1 70.3 190.0 7.6 6.1 51.8 9.6 SORL1 "C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1" ENSG00000137642 "Sortilin related receptor 1" Q92673 11 121452314-121633763 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Transport" Receptor "Alzheimer disease, Amyloidosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 79.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 387.8;Excitatory neurons: 247.4;Microglial cells: 404.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 125.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 125.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 142.8;Daudi: 68.7;OE19: 93.5;RT4: 102.1;U-698: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011500, HPA031321" Uncertain "Secreted to blood" NA NA 79000 "Cluster 5: Granulocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB011500: AB_443414, HPA031321: AB_2673826" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.08e-2)" "unprognostic (9.53e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-3)" "unprognostic (1.74e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.80e-7)" "unprognostic (2.48e-1)" "unprognostic (1.87e-1)" "unprognostic (5.07e-2)" "unprognostic (1.21e-2)" 7.0 6.1 29.1 24.4 39.1 47.4 13.9 49.5 35.5 44.4 0.0 17.3 11.6 5.4 8.9 5.4 40.1 7.3 2.4 33.8 39.7 19.0 58.2 10.4 21.1 40.3 46.8 9.0 8.0 10.4 16.8 2.3 47.0 20.8 16.9 20.3 21.8 25.4 1.7 3.4 18.1 4.5 45.3 21.8 10.3 5.1 38.8 17.0 13.5 4.0 23.0 15.7 6.6 79.1 1.3 8.1 7.3 1.1 0.0 0.0 7.4 0.4 2.4 0.3 0.0 11.9 142.8 68.7 8.5 1.8 10.5 47.4 9.1 7.0 0.1 0.0 2.6 0.0 10.3 16.8 0.1 29.6 0.1 0.0 7.6 0.0 25.8 4.0 0.0 8.7 0.0 0.7 0.0 9.7 7.1 15.3 8.8 93.5 10.8 7.7 0.4 1.6 15.8 102.1 5.1 1.5 15.2 21.5 0.0 16.0 21.0 9.5 0.3 0.1 4.9 1.0 0.0 0.0 0.0 139.8 0.1 38.6 0.4 44.3 15.9 59.1 22.1 6.9 29.3 1.9 24.6 20.0 6.6 5.1 23.1 20.8 125.7 20.9 9.4 16.4 19.3 21.2 29.1 39.1 49.5 35.5 33.8 39.7 40.3 46.8 47.0 45.3 38.8 79.1 1.6 6.4 23.3 160.9 20.7 4.5 42.3 23.3 18.2 68.8 44.5 22.0 12.3 18.6 36.8 79.1 387.8 0.4 130.1 132.1 0.0 10.3 1.2 21.6 2.9 10.3 6.1 8.8 247.4 0.7 0.7 5.8 14.3 24.7 12.0 20.6 34.6 114.5 39.1 50.5 80.1 54.6 40.7 62.4 16.9 5.0 77.9 67.0 3.6 404.7 97.5 28.0 146.2 74.9 86.0 6.4 81.1 57.9 28.6 36.1 168.6 1.0 15.6 31.2 0.0 19.5 10.3 2.9 18.8 20.8 2.4 0.4 60.2 32.7 42.2 33.4 SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 111.3;stomach 1: 60.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 68.5;Distal tubular cells: 29.4;Gastric mucus-secreting cells: 76.5;Horizontal cells: 30.3;Ionocytes: 128.1;Melanocytes: 32.0" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;EFO-21: 12.7;HEL: 4.8;NTERA-2: 4.9;RPTEC TERT1: 23.5" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" 0.2 0.5 1.3 0.9 2.7 0.1 17.9 1.7 3.4 2.6 111.3 10.9 11.6 4.7 0.3 3.7 5.0 0.3 3.1 3.7 0.3 22.3 0.0 39.2 0.1 0.7 0.9 1.1 0.6 0.6 2.4 0.0 0.1 1.8 15.0 3.0 15.6 3.5 0.1 16.8 8.6 1.1 0.2 0.1 60.4 1.9 2.2 0.1 8.6 0.9 3.9 1.4 3.5 1.8 0.0 0.0 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 12.7 0.0 0.0 0.3 0.4 0.0 0.0 0.1 2.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.3 0.1 0.0 0.1 0.7 0.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.7 1.7 3.4 3.7 0.3 0.7 0.9 0.1 0.2 2.2 1.8 0.4 0.0 0.0 0.0 0.2 5.6 4.3 2.1 9.1 0.6 68.5 17.8 3.8 0.0 2.0 14.7 0.0 0.0 0.4 1.2 29.4 0.0 19.7 1.0 0.1 2.9 2.4 0.0 0.0 0.0 0.0 3.9 76.5 1.5 0.0 0.0 0.4 0.1 0.0 30.3 0.0 0.2 128.1 0.0 1.2 13.0 7.2 0.4 32.0 0.0 0.0 14.2 0.0 0.0 0.0 0.4 2.2 2.6 0.4 1.1 0.0 21.8 0.0 0.7 0.0 0.1 0.3 3.4 1.2 14.1 7.2 0.0 0.9 0.0 2.3 1.5 SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.4;skin 1: 48.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 209.2;Basal squamous epithelial cells: 447.3;Squamous epithelial cells: 388.1;Suprabasal keratinocytes: 169.9" "Cancer enhanced" "Detected in many" "testis cancer: 67.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Group enriched" "Detected in many" 8 "A-431: 130.6;HaCaT: 142.1;HBEC3-KT: 57.8;hTCEpi: 56.6" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Golgi apparatus, Vesicles" "HPA067196: AB_2685802, HPA074049: AB_2686656" "unprognostic (5.79e-3)" "unprognostic (6.65e-2)" "unprognostic (1.40e-2)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.60e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (5.00e-2)" "unprognostic (8.50e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.95e-2)" "unprognostic (2.97e-1)" 2.2 0.9 15.0 0.8 14.6 2.7 3.4 17.4 23.3 21.1 11.8 12.4 0.7 8.2 1.7 87.4 11.0 1.0 8.6 14.5 15.3 1.7 1.3 1.5 0.5 14.3 15.0 15.3 1.0 0.2 7.9 0.3 14.1 12.1 0.5 5.0 14.6 7.1 2.3 48.2 3.5 1.3 14.5 1.1 4.7 2.6 14.7 1.0 2.3 1.8 2.8 10.4 32.7 15.0 130.6 3.2 1.8 1.0 0.1 0.3 9.6 1.4 0.5 1.1 1.7 2.5 0.8 0.4 1.2 0.1 0.4 142.1 0.1 57.8 0.4 3.3 3.9 0.5 1.7 0.5 0.2 0.3 2.6 0.0 56.6 0.7 11.9 3.6 0.0 2.6 2.9 0.8 0.2 0.9 0.6 1.5 3.6 0.3 0.7 1.6 1.8 1.0 2.7 0.7 0.8 2.2 1.5 0.5 0.7 5.5 1.1 1.0 1.6 1.3 2.3 1.6 4.4 0.9 1.5 1.6 4.4 1.7 3.2 0.1 2.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.6 1.0 0.0 0.4 15.0 14.6 17.4 23.3 14.5 15.3 14.3 15.0 14.1 14.5 14.7 15.0 0.8 0.0 0.0 2.6 0.1 209.2 51.8 72.7 447.3 13.6 6.3 13.0 4.7 0.0 20.6 1.8 14.6 1.7 0.7 0.5 1.9 0.1 0.2 0.4 4.9 3.1 1.2 0.0 8.1 0.5 2.0 10.4 0.0 0.4 0.0 1.3 1.4 0.0 0.4 10.1 7.7 0.4 10.2 1.2 19.3 1.1 31.4 0.9 26.6 1.0 1.2 50.0 0.0 4.0 2.4 0.5 0.1 36.9 4.9 21.2 0.3 0.2 16.2 9.4 32.9 7.8 7.1 0.7 10.9 388.1 169.9 1.1 1.1 0.6 0.8 73.8 SOX5 "L-SOX5, MGC35153" ENSG00000134532 "SRY-box transcription factor 5" P35711 12 23529504-24562544 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 32.3" "Cell type enhanced" "Detected in many" "Astrocytes: 1531.5;Excitatory neurons: 615.9;Inhibitory neurons: 717.3;Oligodendrocyte precursor cells: 1437.1" "Cancer enhanced" "Detected in many" "melanoma: 3.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 1.5;naive B-cell: 1.3" "Lineage enriched" "Detected in single" 5 "B-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 17.3;Daudi: 18.3;HDLM-2: 38.3;K-562: 17.0;WM-115: 14.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060499 Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA060499: AB_2684294" "unprognostic (9.11e-4)" "unprognostic (4.64e-3)" "unprognostic (3.23e-1)" "unprognostic (6.83e-2)" "unprognostic (1.67e-1)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.03e-3)" "unprognostic (1.36e-1)" "unprognostic (8.40e-2)" "unprognostic (1.70e-4)" "unprognostic (6.95e-2)" "unprognostic (4.53e-4)" "unprognostic (3.12e-3)" "unprognostic (2.37e-1)" "unprognostic (9.59e-2)" "unprognostic (2.75e-2)" 5.8 1.1 6.3 1.7 9.6 0.4 1.5 0.4 10.3 6.9 0.0 1.3 0.7 5.0 1.2 1.2 3.6 3.0 2.4 6.4 7.6 1.8 11.1 2.7 3.7 2.9 5.8 7.7 1.1 0.4 0.4 8.8 5.6 2.1 1.2 3.7 3.2 3.1 0.6 6.3 1.1 2.7 3.1 1.3 1.1 32.3 6.8 0.6 2.0 1.7 3.1 1.3 0.6 5.0 0.2 0.2 17.3 0.0 9.6 5.1 0.0 0.2 0.0 0.2 0.5 3.1 0.1 18.3 0.8 0.0 0.0 0.2 9.9 0.0 0.3 38.3 2.4 3.9 0.1 8.4 6.6 0.1 0.2 2.7 0.0 0.9 0.0 2.2 0.0 0.6 17.0 0.8 0.3 0.0 7.1 0.1 5.5 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.8 0.8 0.0 0.0 6.7 4.3 0.3 3.6 0.0 0.3 2.1 0.0 1.7 0.4 0.0 1.1 4.0 0.1 14.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 6.3 9.6 0.4 10.3 6.4 7.6 2.9 5.8 5.6 3.1 6.8 5.0 4.5 6.4 11.0 1531.5 3.7 13.3 0.1 0.0 1.8 11.9 1.0 1.3 4.0 1.5 3.1 3.7 0.0 0.1 0.0 0.0 0.0 0.2 198.7 18.7 55.7 4.0 5.4 0.4 615.9 0.0 0.2 11.3 1.5 21.2 1.3 13.3 3.6 22.0 0.3 0.0 717.3 0.0 0.0 0.8 1.9 208.6 10.2 0.8 12.4 279.2 5.7 17.9 0.0 1437.1 24.4 0.0 0.0 6.8 1.2 0.1 0.4 0.6 13.8 2.6 19.7 2.8 24.7 97.0 1.4 0.5 12.1 0.3 0.7 0.2 0.2 0.2 SOX6 ENSG00000110693 "SRY-box transcription factor 6" P35712 11 15966449-16739591 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.9" "Cell type enhanced" "Detected in many" "Astrocytes: 308.9;Early spermatids: 256.8;Inhibitory neurons: 481.0;Oligodendrocyte precursor cells: 1687.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.0" "Cell line enhanced" "Detected in some" "CACO-2: 5.7;HAP1: 4.4;hTCEpi: 5.0;SK-MEL-30: 4.9;WM-115: 18.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001923, HPA003908" Enhanced Supported Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA001923: AB_1080065, HPA003908: AB_1080063" "unprognostic (3.40e-2)" "unprognostic (1.70e-1)" "unprognostic (1.20e-1)" "unprognostic (1.68e-1)" "unprognostic (4.17e-3)" "unprognostic (1.05e-2)" "unprognostic (6.47e-3)" "unprognostic (1.25e-2)" "unprognostic (1.31e-1)" "unprognostic (7.89e-4)" "unprognostic (9.08e-2)" "unprognostic (7.37e-3)" "prognostic favorable (6.47e-12)" "unprognostic (9.90e-2)" "unprognostic (5.02e-2)" "unprognostic (1.15e-1)" "unprognostic (3.04e-2)" 1.8 1.3 5.4 0.4 5.9 26.9 0.7 2.6 4.7 1.7 5.5 1.2 6.5 0.6 2.0 2.1 4.0 2.6 3.0 4.0 7.2 11.1 4.8 0.8 0.1 7.2 7.8 0.7 6.8 0.1 2.9 2.5 6.0 0.4 1.3 3.2 0.5 0.6 9.3 5.8 11.0 0.5 7.7 0.5 1.0 14.4 4.1 1.6 3.4 5.9 0.2 0.8 0.8 6.8 0.0 0.7 3.9 3.7 0.0 0.0 0.0 0.3 1.3 0.1 0.1 5.7 0.0 0.0 3.6 0.0 0.0 0.1 4.4 1.1 0.0 0.0 0.5 0.0 0.0 0.3 0.6 0.0 0.0 0.0 5.0 0.0 0.1 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.8 0.0 1.8 0.0 0.0 0.1 0.4 0.0 4.9 0.5 0.0 0.0 0.0 2.6 2.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 5.4 5.9 2.6 4.7 4.0 7.2 7.2 7.8 6.0 7.7 4.1 6.8 2.7 3.2 6.3 308.9 1.0 40.1 5.8 6.8 66.6 26.3 3.7 2.5 21.6 54.3 3.8 36.8 10.4 1.3 0.1 1.4 9.8 19.8 256.8 29.4 5.3 4.8 7.8 126.7 2.8 3.7 0.6 14.5 2.0 27.8 0.0 1.6 2.2 7.5 1.1 0.0 481.0 6.6 0.0 2.9 3.2 70.1 3.4 1.4 35.6 21.5 0.0 48.4 0.0 1687.9 8.9 5.5 20.3 2.2 0.1 3.2 99.8 27.1 8.3 4.3 0.0 26.2 14.6 22.1 4.5 32.7 16.1 0.5 1.1 3.0 11.8 3.7 SOX8 ENSG00000005513 "SRY-box transcription factor 8" P57073 16 981770-986979 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 127.4" "Group enriched" "Detected in some" 9 "Muller glia cells: 156.1;Oligodendrocyte precursor cells: 64.3;Oligodendrocytes: 66.0" "Cancer enriched" "Detected in many" 6 "glioma: 46.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RH-30: 114.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041640, HPA058665" Enhanced Nucleoplasm No NA "Cluster 70: Brain - Nervous system development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA041640: AB_10964357, HPA058665: AB_2683792" "unprognostic (1.40e-2)" "unprognostic (2.56e-3)" "unprognostic (1.59e-1)" "unprognostic (3.10e-2)" "unprognostic (4.58e-2)" "unprognostic (7.16e-3)" "unprognostic (6.05e-3)" "unprognostic (3.01e-2)" "unprognostic (2.53e-1)" "unprognostic (1.16e-1)" "unprognostic (4.53e-3)" "unprognostic (4.46e-2)" "unprognostic (1.20e-3)" "unprognostic (8.50e-2)" "unprognostic (6.18e-2)" "unprognostic (5.47e-1)" "unprognostic (9.09e-2)" 0.9 0.5 58.3 0.9 90.4 0.1 1.7 66.7 71.8 1.3 23.6 3.1 0.1 0.4 0.1 0.4 0.6 0.5 4.1 54.0 57.9 0.7 0.2 0.3 2.0 73.6 79.8 0.3 1.0 0.1 1.2 0.4 64.9 1.2 0.6 14.8 8.3 0.4 0.8 5.4 1.8 0.2 58.7 1.0 0.9 2.5 71.2 0.4 0.5 0.6 2.3 1.4 1.6 127.4 0.0 0.6 2.2 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.4 5.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.0 3.3 1.8 0.2 0.0 114.7 4.5 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.4 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 58.3 90.4 66.7 71.8 54.0 57.9 73.6 79.8 64.9 58.7 71.2 127.4 1.5 0.0 0.0 10.1 0.2 0.4 0.5 0.0 0.0 1.8 8.7 10.4 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.6 2.6 0.0 0.0 4.6 0.2 0.1 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.3 0.5 3.4 0.3 1.8 3.7 0.6 156.1 0.0 64.3 66.0 0.1 0.3 1.9 0.5 1.9 0.0 0.0 0.0 8.0 0.0 9.9 0.9 0.0 3.9 0.4 1.0 0.0 0.9 0.1 0.9 0.3 SPAAR "LINC00961, SPAR" ENSG00000235387 "Small regulatory polypeptide of amino acid response" A0A1B0GVQ0 9 35909490-35937153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.4;breast: 10.8" "Cell type enriched" "Detected in some" 7 "Adipocytes: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HUVEC TERT2: 34.0;TIME: 40.1" "Not detected" "Not detected" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.17e-1)" "unprognostic (2.19e-2)" "unprognostic (1.91e-2)" "unprognostic (7.00e-3)" "unprognostic (4.23e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.40e-3)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.72e-2)" "unprognostic (7.12e-3)" "unprognostic (1.67e-2)" "unprognostic (3.04e-1)" "unprognostic (1.27e-1)" "unprognostic (3.22e-1)" 12.4 1.2 2.9 0.6 2.5 0.0 10.8 2.2 3.3 0.7 1.1 1.2 0.3 1.2 0.1 0.5 1.2 0.6 8.9 2.3 2.2 4.2 0.8 3.2 0.4 3.0 2.6 0.7 0.5 0.5 0.6 4.7 3.1 1.0 0.4 1.4 0.7 0.5 3.1 0.9 0.9 0.6 2.3 0.7 0.9 7.5 3.3 0.2 1.9 1.8 0.0 1.5 0.8 2.4 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.6 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.4 0.1 0.2 0.0 0.0 34.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 40.1 0.0 0.8 2.7 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.5 2.2 3.3 2.3 2.2 3.0 2.6 3.1 2.3 3.3 2.4 42.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 5.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 SPAG1 "CILD28, CT140, FLJ32920, HSD-3.8, SP75, TPIS" ENSG00000104450 "Sperm associated antigen 1" Q07617 8 100157906-100259278 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Fertilization Hydrolase "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 96.0;Endometrial ciliated cells: 190.6;Respiratory ciliated cells: 198.6;Spermatocytes: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023748, HPA053682" Enhanced Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA023748: AB_2671304, HPA053682: AB_2682229" "unprognostic (9.95e-2)" "unprognostic (5.37e-2)" "unprognostic (1.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-1)" "unprognostic (2.57e-1)" "unprognostic (5.86e-2)" "unprognostic (9.19e-2)" "unprognostic (1.53e-1)" "unprognostic (5.62e-2)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.87e-4)" "unprognostic (9.11e-3)" "unprognostic (8.83e-3)" "unprognostic (1.54e-1)" "prognostic favorable (2.62e-4)" 1.8 1.3 3.0 3.6 3.2 10.1 3.0 4.2 3.0 5.4 14.0 12.9 2.9 2.4 1.5 7.8 10.0 3.7 1.5 3.0 4.6 3.2 4.7 5.0 2.7 7.2 9.0 1.0 2.5 9.0 5.7 1.8 6.2 3.1 18.3 1.9 4.6 3.5 0.4 7.9 2.7 1.8 6.0 2.0 6.3 19.4 4.8 2.1 3.4 0.6 4.4 5.3 3.0 5.4 31.3 8.3 0.5 1.8 1.8 1.5 4.6 5.7 3.4 6.8 7.1 8.3 13.5 1.2 20.0 1.8 10.1 16.1 5.9 11.1 6.3 18.1 6.1 5.2 9.0 3.1 2.4 1.4 4.5 1.3 5.8 8.4 6.6 5.3 5.8 5.7 0.2 16.1 1.0 11.2 3.1 1.4 0.5 15.6 9.1 0.5 1.3 4.7 26.1 14.8 4.8 3.5 7.8 6.4 7.0 2.2 9.2 5.9 5.3 6.8 9.8 3.6 14.9 10.9 8.9 0.9 6.5 5.0 3.4 0.0 0.1 0.6 0.1 0.0 0.0 0.8 0.1 0.1 0.1 0.3 0.0 0.1 0.7 1.0 0.2 0.2 0.0 0.0 3.0 3.2 4.2 3.0 3.0 4.6 7.2 9.0 6.2 6.0 4.8 5.4 7.7 48.1 22.8 18.9 7.7 5.6 9.6 18.1 2.2 2.0 13.3 7.7 5.6 22.8 37.2 18.4 0.0 1.3 19.0 32.9 5.9 19.7 96.0 190.6 7.1 6.9 22.1 0.4 30.1 8.6 8.7 5.0 22.4 39.5 10.1 7.3 4.2 8.0 2.8 8.4 21.6 14.9 6.1 2.2 5.3 32.3 5.0 3.9 1.8 6.5 4.5 11.5 5.2 4.5 4.1 14.9 17.7 3.8 15.9 10.3 2.4 10.0 198.6 2.3 0.0 4.8 6.4 91.9 4.7 2.9 5.4 2.3 12.0 1.3 20.1 23.3 SPAG16 "DKFZp666P1710, FLJ22724, PF20, WDR29" ENSG00000144451 "Sperm associated antigen 16" Q8N0X2 2 213284379-214410501 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 243.1;Inhibitory neurons: 273.7;Respiratory ciliated cells: 330.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037542 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA037542: AB_10672353" "unprognostic (4.20e-2)" "unprognostic (2.73e-1)" "unprognostic (2.67e-1)" "unprognostic (9.79e-2)" "unprognostic (1.83e-1)" "unprognostic (1.30e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (4.90e-4)" "prognostic favorable (3.82e-4)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-1)" "unprognostic (1.17e-1)" 16.3 16.8 36.6 6.4 37.4 2.4 20.8 35.1 45.9 21.0 39.0 16.5 18.8 18.2 31.6 26.1 46.5 22.0 22.2 34.2 37.8 30.4 18.8 10.8 11.5 38.8 39.6 25.8 15.5 24.4 29.7 9.8 37.8 22.1 17.2 21.5 15.7 20.5 10.3 24.9 10.9 12.1 40.9 8.0 26.1 46.3 38.4 13.0 26.4 10.8 13.8 18.9 19.4 40.6 26.8 9.9 29.4 0.0 19.3 35.0 0.2 14.3 17.1 18.3 19.3 20.8 28.8 11.1 16.7 16.0 29.3 18.5 13.4 17.4 38.6 0.0 10.5 5.8 28.0 24.6 21.9 6.3 0.1 30.1 23.5 16.3 9.5 25.0 7.6 11.6 18.8 12.3 18.4 0.0 21.4 0.1 16.3 0.0 8.7 22.6 30.9 0.5 29.4 25.8 21.4 25.1 16.3 15.1 21.3 24.2 70.3 2.7 7.8 17.2 9.2 9.3 15.1 20.0 9.7 0.4 28.6 0.0 8.0 2.0 0.3 0.9 8.1 1.3 11.7 9.3 9.1 10.4 3.1 8.5 12.0 10.4 0.5 15.4 0.9 5.1 9.4 3.4 36.6 37.4 35.1 45.9 34.2 37.8 38.8 39.6 37.8 40.9 38.4 40.6 17.7 16.0 19.5 89.5 10.7 42.3 46.6 82.8 22.8 47.6 38.0 45.6 67.5 74.4 73.6 40.5 95.9 50.6 7.5 17.1 76.3 44.0 243.1 207.0 31.3 18.5 38.2 9.0 205.9 24.9 20.8 30.8 32.1 30.3 10.1 34.0 12.8 16.9 11.7 40.4 273.7 37.8 101.7 4.6 9.6 86.2 41.3 5.9 23.2 42.2 29.2 82.7 8.2 92.0 74.9 27.3 18.8 44.8 9.4 25.4 9.4 94.9 330.0 69.0 13.1 30.8 36.1 167.9 31.0 64.6 56.4 23.5 12.9 55.3 39.8 53.8 SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;kidney: 37.8;testis: 74.0" "Cell type enhanced" "Detected in many" "Early spermatids: 126.0;Erythroid cells: 37.2;Spermatocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 11.7;T-reg: 4.9" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 4.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: AB_1853519, HPA022479: AB_1853521, HPA024418: " "unprognostic (4.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.31e-3)" "unprognostic (2.32e-3)" "unprognostic (3.50e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (5.43e-5)" "unprognostic (3.37e-3)" "unprognostic (4.84e-3)" "unprognostic (5.97e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (3.49e-2)" "prognostic unfavorable (5.43e-13)" "unprognostic (2.64e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-2)" "unprognostic (2.01e-1)" 2.2 3.3 7.8 7.8 7.6 37.9 2.4 5.8 9.1 2.6 3.4 8.3 7.9 1.9 2.4 8.3 1.7 1.8 1.4 7.6 7.7 37.8 14.8 3.4 14.5 6.7 6.8 2.7 1.5 1.1 4.3 5.7 6.7 2.2 10.7 10.8 2.4 0.8 1.0 5.5 9.1 3.4 5.0 7.4 3.6 74.0 7.7 22.4 8.7 0.7 17.3 2.6 3.6 7.5 84.7 87.7 103.3 78.4 5.2 8.6 42.4 65.9 42.4 98.1 78.3 69.2 25.5 59.8 34.2 46.8 91.7 70.2 114.5 42.7 103.8 108.6 72.9 62.9 87.9 80.2 0.6 83.1 76.1 2.9 3.8 78.6 40.4 14.5 52.1 90.6 69.7 101.5 80.7 52.6 109.4 92.9 54.2 68.3 44.5 72.1 144.4 70.9 29.0 43.0 78.6 45.8 96.4 114.9 31.6 84.9 82.2 70.6 25.7 56.4 91.3 46.6 114.6 46.7 72.9 87.3 37.8 60.6 91.8 11.7 0.0 0.0 0.4 0.4 0.7 0.6 1.2 0.9 0.1 1.4 1.1 0.9 0.2 0.8 0.3 0.3 4.9 0.9 7.8 7.6 5.8 9.1 7.6 7.7 6.7 6.8 6.7 5.0 7.7 7.5 0.5 3.2 1.7 0.7 3.3 2.0 0.9 1.3 1.2 5.0 1.1 1.0 0.7 0.0 1.9 0.0 0.0 9.0 1.3 4.7 1.9 0.5 126.0 6.0 1.1 1.5 13.1 37.2 5.2 0.4 12.2 2.6 5.1 1.8 1.3 12.6 3.3 6.3 6.5 3.3 6.0 4.6 4.1 2.7 4.0 25.2 0.9 6.1 0.0 1.9 0.9 0.7 0.0 2.0 1.7 0.4 4.7 0.0 13.1 0.8 8.1 12.5 7.7 3.9 6.6 2.0 2.2 72.6 21.0 5.2 1.0 3.8 2.8 0.9 5.1 1.1 SPAG6 "CFAP194, CT141, FAP194, PF16, Repro-SA-1" ENSG00000077327 "Sperm associated antigen 6" O75602 10 22345445-22454224 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 63.5;fallopian tube: 49.0;testis: 96.3" "Cell type enhanced" "Detected in some" "Early spermatids: 228.6;Endometrial ciliated cells: 73.2;Respiratory ciliated cells: 266.4;Spermatocytes: 372.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "U-937: 105.6" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "midbrain: 11.1" HPA038440 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA038440: AB_10671742" "unprognostic (5.02e-2)" "unprognostic (9.52e-2)" "unprognostic (8.94e-6)" "unprognostic (2.21e-1)" "unprognostic (2.51e-2)" "unprognostic (4.91e-3)" "unprognostic (1.68e-1)" "unprognostic (2.38e-1)" "unprognostic (8.68e-2)" "unprognostic (1.07e-2)" "unprognostic (2.52e-1)" "unprognostic (1.26e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-3)" "unprognostic (3.10e-2)" "unprognostic (2.78e-4)" 0.0 0.0 4.2 0.0 4.0 0.4 1.7 1.9 1.4 1.7 63.5 0.0 0.0 0.2 0.4 0.0 49.0 0.0 0.1 3.3 5.0 0.3 0.1 7.0 0.1 17.6 16.1 0.1 0.3 1.8 14.6 0.0 9.9 1.0 0.0 5.8 0.0 0.0 0.0 0.3 0.0 0.0 16.3 0.0 0.0 96.3 6.4 0.4 0.1 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.9 2.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.3 0.0 2.5 0.0 0.0 0.0 0.0 0.1 1.7 0.8 0.2 0.0 105.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 4.2 4.0 1.9 1.4 3.3 5.0 17.6 16.1 9.9 16.3 6.4 10.1 0.0 0.0 4.8 0.0 0.1 0.1 0.1 14.0 0.0 0.2 0.5 0.3 0.6 0.0 24.5 0.0 0.0 0.1 0.2 0.1 1.9 0.3 228.6 73.2 0.4 0.2 0.0 0.0 7.1 0.0 0.0 0.7 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 3.1 0.0 16.2 0.0 0.2 51.4 5.0 0.5 1.8 4.7 0.0 0.3 0.0 0.5 6.0 0.4 0.0 4.9 0.3 1.8 0.0 1.4 266.4 1.2 0.0 0.0 3.7 372.6 4.8 0.0 0.1 0.0 0.5 0.1 0.0 0.1 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPARCL1 MAST9 ENSG00000152583 "SPARC like 1" Q14515 4 87473335-87531061 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 4430.9;Endothelial cells: 2372.1;Peritubular cells: 2523.5;Sertoli cells: 4674.1;Skeletal myocytes: 2379.0;Smooth muscle cells: 2781.9" "Cancer enhanced" "Detected in all" "glioma: 528.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 24.9;SuSa: 31.4;U-266/70: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026225 Enhanced "Secreted in other tissues" NA NA 630000000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB026225: " "unprognostic (1.02e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.63e-3)" "unprognostic (1.73e-2)" "unprognostic (3.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (2.45e-3)" "unprognostic (1.76e-2)" "unprognostic (5.72e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (3.33e-4)" 755.6 129.5 664.6 124.5 810.9 0.5 532.1 612.4 1058.4 732.7 580.4 624.3 125.1 1244.5 443.8 308.1 754.5 487.9 600.2 744.6 723.5 72.5 25.0 481.1 99.1 655.7 730.9 286.8 91.8 128.0 197.8 315.4 663.4 584.2 187.5 95.2 228.3 999.2 244.8 130.2 280.1 1191.2 774.7 157.9 347.7 97.5 694.8 103.2 369.9 594.7 100.0 488.0 466.4 681.2 0.7 0.0 24.9 0.3 0.2 0.1 2.6 0.1 0.1 0.0 0.0 0.0 0.1 0.4 1.8 0.0 0.0 1.4 2.4 0.0 0.0 1.7 0.0 0.3 1.1 0.4 1.1 0.3 1.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.3 0.0 0.5 0.2 3.5 0.6 0.0 0.0 0.3 0.4 1.2 0.0 0.1 0.8 1.6 0.1 0.2 0.1 31.4 0.4 0.5 0.0 0.2 0.3 1.5 0.2 9.1 1.4 0.6 3.4 0.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 664.6 810.9 612.4 1058.4 744.6 723.5 655.7 730.9 663.4 774.7 694.8 681.2 4430.9 12.8 56.4 1155.7 6.2 46.3 187.2 0.6 59.7 10.7 24.4 251.6 334.2 4.3 43.3 7.3 2.1 2.2 8.6 0.0 13.7 0.8 11.8 34.9 935.8 2372.1 0.0 32.0 382.3 0.4 3.2 1413.1 6.1 46.7 7.6 1.4 899.5 9.1 9.2 3.3 450.1 0.0 0.0 5.3 55.2 47.0 659.5 31.6 56.9 261.4 0.0 179.4 0.0 210.6 53.8 0.1 0.0 2523.5 25.2 50.4 0.0 24.6 7.4 34.4 4674.1 2379.0 2781.9 5.7 7.9 56.8 39.9 2.5 26.9 38.8 0.0 124.2 SPATA18 FLJ32906 ENSG00000163071 "Spermatogenesis associated 18" Q8TC71 4 52051304-52097299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 68.3;testis: 28.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2341.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 31.5;BEWO: 24.4;BJ hTERT+: 15.9;HSkMC: 29.3;hTCEpi: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036854, HPA036855" Enhanced Supported Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA036854: AB_10670927, HPA036855: AB_2675352" "unprognostic (6.54e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.32e-5)" "unprognostic (1.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.27e-2)" "unprognostic (4.49e-2)" "unprognostic (1.76e-1)" "unprognostic (2.73e-1)" "unprognostic (3.13e-1)" "unprognostic (3.13e-2)" "prognostic favorable (3.73e-9)" "unprognostic (4.38e-1)" "unprognostic (1.39e-1)" "unprognostic (1.01e-2)" "unprognostic (4.00e-2)" 2.1 5.0 2.4 0.7 2.2 0.0 6.3 1.3 1.0 10.7 15.6 4.1 2.1 4.2 2.0 4.6 68.3 6.7 1.8 2.5 2.7 5.3 5.4 8.0 0.3 6.8 8.3 1.8 2.0 4.5 4.9 1.9 5.5 4.2 5.6 0.1 10.1 5.6 0.8 6.6 2.2 3.1 6.0 0.6 4.9 28.8 2.6 3.2 1.2 1.3 0.9 2.8 3.4 3.8 0.0 3.8 1.8 0.0 12.7 31.5 24.4 9.3 15.9 0.6 0.7 0.0 1.5 0.0 0.0 12.3 0.2 0.3 0.1 7.1 0.3 0.0 1.1 0.0 0.0 8.0 11.2 0.0 0.0 29.3 28.7 1.0 4.5 5.1 6.9 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.9 2.0 1.0 0.0 0.0 9.7 0.0 0.2 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.2 1.3 1.0 2.5 2.7 6.8 8.3 5.5 6.0 2.6 3.8 0.3 9.6 3.0 0.3 0.0 5.2 8.5 9.4 8.6 0.0 6.0 6.7 2.2 8.6 15.1 0.0 0.0 1.7 0.3 1.8 1.9 1.2 561.1 124.6 1.8 1.2 1.8 0.0 1.7 2.6 1.8 4.3 11.2 4.7 2.5 1.9 1.4 3.4 0.3 0.0 0.5 1.6 6.1 0.6 1.6 2341.5 10.8 1.1 0.0 2.8 0.1 0.0 0.0 0.5 0.1 2.0 2.7 10.9 0.0 5.1 1.9 7.4 141.4 0.0 0.0 1.8 3.9 13.9 7.1 7.1 7.5 0.8 0.2 2.5 4.3 6.8 SPATA3 TSARG1 ENSG00000173699 "Spermatogenesis associated 3" Q8NHX4 2 230990324-231025055 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 179 "testis: 176.7" "Cell type enriched" "Detected in some" 6 "Late spermatids: 5258.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA018254 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA018254: AB_1857419" "unprognostic (6.94e-3)" "unprognostic (6.98e-2)" "unprognostic (9.62e-2)" 0.0 0.0 0.4 0.0 0.5 0.1 0.1 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 176.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.4 0.5 0.5 0.5 0.6 0.4 0.2 0.9 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 783.7 0.0 0.0 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5258.5 22.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 23.9 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPATA31D1 "FAM75D1, FLJ46321" ENSG00000214929 "SPATA31 subfamily D member 1" Q6ZQQ2 9 81988772-81995253 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 112 "testis: 11.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 10.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047897 Uncertain NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA047897: AB_2680204" "unprognostic (1.25e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPATA5L1 "FLJ12286, MGC5347" ENSG00000171763 "Spermatogenesis associated 5 like 1" Q9BVQ7 15 45402336-45421415 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043679 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Nucleoli "HPA043679: AB_10964179" "unprognostic (6.22e-2)" "unprognostic (3.34e-2)" "unprognostic (7.03e-2)" "unprognostic (1.57e-2)" "unprognostic (9.67e-2)" "unprognostic (6.85e-2)" "unprognostic (2.46e-2)" "unprognostic (3.13e-2)" "unprognostic (3.69e-2)" "unprognostic (3.69e-1)" "unprognostic (4.97e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.40e-2)" "unprognostic (2.98e-2)" "unprognostic (2.55e-2)" "unprognostic (2.72e-2)" "unprognostic (4.80e-2)" 4.5 4.9 4.7 4.6 5.1 6.3 4.5 5.5 6.2 5.5 4.4 5.2 5.9 4.4 3.9 10.0 5.0 2.7 5.7 4.9 5.0 6.0 7.5 3.3 4.6 4.9 4.8 6.1 5.8 4.3 3.1 5.2 5.0 4.2 4.8 4.6 4.4 3.9 8.9 7.4 5.5 4.4 5.0 4.5 4.5 3.4 5.2 4.9 5.3 5.4 5.0 5.4 6.0 5.6 10.0 6.3 9.9 7.3 8.0 7.8 12.0 8.7 7.9 9.3 9.0 17.3 6.3 7.3 9.5 5.8 16.9 22.5 14.8 10.9 10.3 10.0 8.4 9.5 11.2 13.6 9.0 12.8 4.0 6.2 12.2 7.7 10.1 10.6 7.4 9.4 15.6 11.4 10.5 6.7 8.9 24.5 7.1 24.8 9.7 9.8 13.9 6.8 11.7 9.8 13.5 6.9 7.2 15.5 8.4 11.7 13.7 23.1 4.7 4.5 6.9 27.8 18.8 9.7 20.8 11.3 11.6 20.8 8.3 0.0 0.9 1.2 1.1 0.7 0.4 0.6 0.7 1.5 0.9 0.7 0.6 0.9 1.1 1.1 1.9 1.0 0.8 0.2 4.7 5.1 5.5 6.2 4.9 5.0 4.9 4.8 5.0 5.0 5.2 5.6 4.7 0.0 1.1 7.2 8.9 5.0 8.9 4.6 5.2 7.9 3.7 2.4 6.9 7.2 5.2 3.7 16.7 12.2 7.3 5.4 3.9 6.2 20.6 6.2 5.4 6.3 3.6 2.5 11.0 7.3 11.9 5.2 9.2 8.4 4.5 8.6 1.1 5.7 8.0 6.7 10.1 6.3 0.0 3.7 7.6 7.1 7.8 7.7 3.6 6.5 7.7 5.0 2.1 16.6 14.6 5.5 3.1 3.8 8.5 6.2 9.2 5.7 2.4 6.5 0.0 4.1 4.1 6.2 5.6 10.4 6.8 6.7 5.8 6.1 7.3 8.2 SPC24 "FLJ90806, SPBC24" ENSG00000161888 "SPC24 component of NDC80 kinetochore complex" Q8NBT2 19 11131520-11155808 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.0;lymphoid tissue: 14.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.0;Extravillous trophoblasts: 15.5;Hofbauer cells: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA051234 Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA051234: AB_2681397" "unprognostic (1.57e-1)" "prognostic favorable (3.59e-4)" "unprognostic (6.79e-2)" "unprognostic (1.07e-3)" "unprognostic (4.04e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.21e-2)" "unprognostic (1.69e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (6.12e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.62e-2)" "unprognostic (3.52e-2)" "unprognostic (2.25e-1)" "unprognostic (8.82e-2)" 1.9 1.7 1.3 4.8 1.5 26.0 1.2 3.9 2.1 2.1 1.7 4.7 4.5 2.7 0.8 5.0 1.3 2.3 2.7 1.6 1.5 0.8 1.6 1.6 6.3 1.1 0.8 1.3 1.1 0.4 0.4 3.2 1.3 1.6 4.3 1.2 1.3 2.0 4.0 3.9 4.1 8.1 0.5 3.1 2.9 4.3 1.4 14.7 0.9 1.1 6.5 2.5 2.0 2.4 73.6 26.9 36.9 30.1 5.0 9.7 16.6 42.3 15.7 38.6 43.6 28.4 24.6 58.2 46.0 18.5 22.8 38.8 29.0 30.3 28.7 30.9 24.9 78.5 68.9 43.2 1.1 55.5 33.7 1.9 1.1 27.8 12.8 10.0 34.7 62.3 42.8 118.3 27.6 48.7 76.4 32.9 25.5 19.8 43.9 59.8 56.7 18.6 11.2 23.8 38.4 27.2 37.0 22.4 9.6 17.5 22.0 19.8 33.2 36.8 38.3 49.6 51.2 70.5 39.8 55.6 26.9 53.9 30.5 1.9 0.4 0.4 0.5 0.5 0.4 0.8 0.9 1.5 0.2 0.7 0.9 0.6 2.2 2.0 0.5 0.5 1.7 0.3 1.3 1.5 3.9 2.1 1.6 1.5 1.1 0.8 1.3 0.5 1.4 2.4 0.2 0.0 0.5 0.3 1.5 1.1 1.2 1.3 0.0 0.0 1.0 0.4 9.0 1.5 0.8 5.5 6.2 10.0 0.9 2.8 0.0 0.2 0.3 1.0 2.2 2.2 2.4 35.0 0.3 0.0 15.5 3.5 3.6 1.8 5.7 6.5 4.6 0.7 14.0 0.0 0.3 2.6 0.0 3.0 2.5 3.0 0.6 1.0 0.0 1.0 0.0 2.1 2.1 0.5 0.3 0.3 0.0 0.4 6.3 0.3 0.7 0.6 0.2 0.6 0.0 1.3 2.4 6.9 10.8 2.1 0.3 2.1 2.2 0.5 6.6 1.2 SPC25 "AD024, MGC22228, SPBC25" ENSG00000152253 "SPC25 component of NDC80 kinetochore complex" Q9HBM1 2 168834132-168913371 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.5;Erythroid cells: 29.9;Extravillous trophoblasts: 37.9;Muller glia cells: 17.2;Spermatocytes: 26.2;Spermatogonia: 20.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047144, HPA050544" Enhanced Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA047144: AB_2679952, HPA050544: " "unprognostic (3.52e-2)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.15e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (4.74e-6)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.84e-3)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.30e-2)" "unprognostic (1.11e-16)" "unprognostic (9.91e-3)" "unprognostic (1.85e-1)" "unprognostic (3.43e-1)" "unprognostic (1.57e-1)" 0.6 0.8 0.6 0.7 0.6 4.2 1.0 0.3 1.5 0.7 0.5 2.1 3.7 0.5 0.0 4.4 0.3 0.5 0.4 1.6 0.7 1.1 0.8 0.9 3.9 0.6 0.7 0.5 1.3 0.1 0.1 1.1 0.8 0.4 1.6 1.7 1.0 0.0 0.6 1.1 2.1 1.0 0.1 2.1 1.6 3.4 0.6 8.5 0.2 0.1 3.7 0.5 1.5 1.8 1.0 16.8 40.6 22.8 1.8 1.9 14.5 22.9 9.3 23.5 18.1 5.6 16.2 15.7 9.0 3.4 31.9 20.9 15.9 0.0 20.7 10.0 21.5 30.2 7.2 2.2 0.1 20.3 8.9 0.3 1.0 14.3 0.0 4.7 10.3 28.2 0.8 15.7 6.4 9.8 16.1 26.3 0.9 11.2 21.0 28.8 38.1 5.6 9.6 13.7 30.4 0.5 16.8 14.4 3.9 13.5 0.4 16.4 2.5 3.6 42.1 13.4 18.2 31.4 56.0 12.5 4.1 0.5 14.3 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.6 0.6 0.3 1.5 1.6 0.7 0.6 0.7 0.8 0.1 0.6 1.8 0.4 0.0 1.1 0.7 4.2 5.4 1.5 7.1 1.2 0.0 1.5 2.4 0.6 0.0 2.6 0.0 0.0 23.5 1.5 3.7 0.0 0.2 2.0 0.5 1.8 1.6 0.0 29.9 0.3 0.0 37.9 4.6 2.0 1.8 0.0 10.1 2.9 1.2 15.1 0.0 0.5 5.2 2.0 1.9 2.4 1.6 0.6 2.0 0.0 0.0 0.0 17.2 0.0 5.0 0.2 0.5 0.1 1.2 15.3 1.0 1.0 0.2 0.1 0.6 0.0 1.3 4.4 26.2 20.1 7.3 1.4 5.7 2.7 1.7 9.9 2.5 SPDEF "bA375E1.3, PDEF" ENSG00000124664 "SAM pointed domain containing ETS transcription factor" O95238 6 34537802-34556333 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 140.7;salivary gland: 114.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 94.2;Breast myoepithelial cells: 61.1;Intestinal goblet cells: 315.1;Prostatic glandular cells: 72.7" "Cancer enhanced" "Detected in many" "prostate cancer: 388.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MCF7: 288.4;OE19: 118.0;SK-BR-3: 192.2;T-47d: 154.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 2.9" HPA055707 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli" Cytosol "HPA055707: AB_2682894" "unprognostic (2.98e-1)" "unprognostic (9.68e-2)" "unprognostic (2.84e-1)" "prognostic favorable (9.26e-9)" "unprognostic (1.57e-1)" "unprognostic (7.10e-3)" "unprognostic (2.56e-2)" "unprognostic (1.15e-1)" "unprognostic (1.63e-1)" "unprognostic (7.39e-3)" "unprognostic (3.48e-3)" "unprognostic (2.92e-1)" "unprognostic (6.16e-11)" "unprognostic (8.04e-2)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-2)" 0.4 0.1 0.5 1.4 0.5 0.1 36.6 0.8 1.1 28.0 0.0 18.4 11.6 9.0 0.5 2.2 6.3 2.4 0.4 0.5 0.2 0.1 0.1 1.1 0.0 0.3 0.4 0.1 0.6 0.0 0.2 0.0 0.2 140.7 10.2 0.0 114.8 0.1 0.3 9.3 14.3 0.6 0.1 0.1 35.4 0.3 0.5 0.0 0.1 0.0 0.0 1.0 0.3 0.5 0.0 30.9 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 288.4 0.3 0.4 0.0 118.0 38.6 0.1 0.0 0.3 0.3 0.3 2.1 0.2 0.0 192.2 0.0 0.0 154.0 0.0 0.0 0.0 0.5 0.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.8 1.1 0.5 0.2 0.3 0.4 0.2 0.1 0.5 0.5 0.8 0.0 2.2 0.7 0.3 0.1 13.3 20.7 0.0 0.0 94.2 61.1 0.3 5.7 31.7 0.0 0.0 0.0 1.4 27.1 0.0 2.6 1.1 6.2 0.7 0.6 5.4 0.0 0.8 1.2 0.0 0.4 28.1 18.7 0.0 0.2 0.4 0.0 0.0 0.0 0.6 315.1 12.2 0.0 0.2 5.5 0.0 0.9 3.6 0.0 0.0 0.0 0.0 0.0 0.2 20.2 12.3 0.0 0.1 72.7 5.7 0.0 2.9 0.0 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.3 0.8 0.0 30.0 11.5 SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "bone marrow: 335.1;lung: 101.0;lymphoid tissue: 172.7" "Group enriched" "Detected in many" 6 "Hofbauer cells: 432.9;Kupffer cells: 411.9;Langerhans cells: 537.6;Macrophages: 453.3;monocytes: 357.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 179.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 179.7" "Cell line enhanced" "Detected in some" "HEL: 90.1;HL-60: 159.7;HMC-1: 282.2;NB-4: 267.8;THP-1: 206.7;U-698: 85.3;U-937: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" 36.5 19.7 12.0 107.3 13.1 335.1 17.7 14.3 19.4 7.9 15.8 15.6 21.5 7.3 2.1 9.1 19.1 21.3 13.5 11.7 16.4 10.6 15.6 101.0 65.0 31.2 20.9 5.2 7.8 3.1 7.6 28.0 24.7 10.3 10.2 1.0 14.6 6.1 5.0 13.8 29.3 21.9 19.8 172.7 17.0 3.7 26.2 15.7 8.8 8.3 32.0 29.9 7.6 30.3 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.2 0.1 0.0 0.0 72.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 0.0 159.7 282.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.7 0.0 0.0 0.2 267.8 0.2 0.0 0.0 48.7 0.2 47.5 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 206.7 0.3 0.0 0.5 0.5 0.1 0.1 0.3 85.3 0.3 117.5 0.1 14.1 19.2 179.7 0.0 27.4 0.0 3.9 0.0 0.0 16.4 2.4 0.0 0.0 83.8 0.0 34.7 0.9 0.0 7.3 12.0 13.1 14.3 19.4 11.7 16.4 31.2 20.9 24.7 19.8 26.2 30.3 2.1 3.2 1.1 10.4 72.6 10.5 0.5 0.0 1.2 1.3 2.1 5.0 2.9 4.3 0.6 5.5 0.0 2.3 6.3 0.5 19.6 0.1 7.5 0.1 0.3 5.5 4.2 39.7 3.1 0.4 3.1 2.6 1.1 0.3 33.7 0.2 7.9 3.2 432.9 0.0 3.3 0.3 0.0 411.9 537.6 27.5 1.8 453.3 10.6 36.5 357.5 7.0 8.2 3.5 1.5 0.0 0.1 0.0 21.8 0.4 0.2 2.3 0.7 1.7 13.1 1.5 1.4 5.1 9.3 0.8 9.9 4.2 4.8 1.1 0.4 0.5 SPINK7 "ECG2, ECRG2" ENSG00000145879 "Serine peptidase inhibitor Kazal type 7" P58062 5 148312419-148315922 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 256.8;esophagus: 620.4;vagina: 614.0" "Cell type enriched" "Detected in some" 7 "Squamous epithelial cells: 49.2" "Group enriched" "Detected in many" 6 "cervical cancer: 4.5;head and neck cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036294 Enhanced "Secreted in other tissues" NA NA 230000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA036294: AB_10671243" "unprognostic (2.82e-1)" "unprognostic (8.99e-3)" "unprognostic (8.52e-3)" "unprognostic (1.81e-1)" "unprognostic (1.12e-2)" "unprognostic (3.37e-2)" "unprognostic (9.10e-2)" "unprognostic (1.49e-1)" "unprognostic (6.86e-2)" "unprognostic (7.24e-2)" "unprognostic (4.22e-2)" 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.3 256.8 0.1 0.1 0.0 0.1 0.1 620.4 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.7 0.0 0.3 0.1 0.0 0.0 140.1 0.0 0.2 9.3 0.1 0.1 0.1 0.1 4.2 0.1 0.2 4.7 0.1 0.1 115.9 0.6 614.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.3 0.1 0.2 0.1 0.2 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 0.0 0.0 0.0 0.0 0.0 4.5 SPINT2 "HAI-2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1371.3;Syncytiotrophoblasts: 1413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 852.5;CAPAN-2: 1219.1;OE19: 1500.4;RPTEC TERT1: 896.7;SK-BR-3: 789.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" 10.5 44.6 56.9 65.3 57.3 81.1 178.5 47.2 66.3 145.6 80.0 297.0 247.4 44.6 269.6 351.9 189.7 105.1 13.6 58.9 92.9 216.1 14.3 138.3 37.4 52.0 54.8 83.3 234.2 252.9 435.9 156.4 56.2 181.8 251.7 23.6 503.9 111.3 1.8 257.0 267.0 19.0 47.6 50.2 219.4 215.7 70.3 82.6 321.3 0.9 101.3 140.1 157.6 51.0 852.5 603.0 3.0 3.4 0.4 0.0 387.4 16.2 1.7 1.2 2.6 426.8 1219.1 6.7 65.8 4.6 1.2 274.6 42.7 587.0 1.4 7.9 51.7 159.4 15.3 0.9 0.9 1.5 0.8 0.1 662.5 0.7 278.6 71.5 2.0 144.2 4.0 0.4 1.0 652.8 25.6 2.8 60.4 1500.4 172.1 87.9 0.6 386.2 896.7 707.4 222.2 3.4 246.5 789.2 2.1 231.0 353.7 104.5 0.7 1.2 4.7 3.4 3.2 56.1 76.4 47.6 1.0 11.2 1.0 515.9 127.4 531.9 3.8 91.1 7.9 143.2 44.2 21.5 297.7 160.4 86.1 80.4 56.4 19.0 64.4 523.5 19.1 142.8 56.9 57.3 47.2 66.3 58.9 92.9 52.0 54.8 56.2 47.6 70.3 51.0 8.0 368.6 233.9 10.4 90.9 376.9 563.9 954.0 278.9 14.3 487.2 518.2 2.8 316.0 655.6 559.1 6.2 1371.3 79.5 1028.3 101.8 866.9 61.8 401.4 47.3 24.3 360.5 83.9 20.7 659.8 502.0 34.6 234.5 490.4 115.5 371.8 32.5 2.0 230.3 3.3 39.8 672.8 734.5 55.5 139.0 55.6 19.0 133.6 88.9 24.4 364.3 129.6 1.0 4.5 9.0 910.4 889.4 17.0 61.3 684.9 918.6 208.8 495.1 17.2 52.6 1.2 76.7 545.2 264.1 507.7 428.3 1413.2 42.6 3.4 582.2 989.6 SPN "CD43, GPL115, LSN" ENSG00000197471 Sialophorin P16150 16 29662979-29670876 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 71.8;lung: 28.3;lymphoid tissue: 51.1" "Cell type enhanced" "Detected in many" "dendritic cells: 131.6;Erythroid cells: 125.9;Macrophages: 65.8;monocytes: 66.4;NK-cells: 352.2;Plasma cells: 60.3;T-cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 218.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 278.8;HL-60: 281.5;HMC-1: 158.3;MOLT-4: 122.2;REH: 98.4;THP-1: 164.1;U-937: 205.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002666, HPA055244" Enhanced Approved "Plasma membrane" NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB002666: , HPA055244: AB_2682756" "prognostic favorable (1.40e-4)" "unprognostic (1.63e-3)" "unprognostic (3.14e-2)" "prognostic favorable (3.08e-5)" "unprognostic (2.68e-2)" "unprognostic (2.49e-3)" "unprognostic (4.02e-2)" "unprognostic (4.17e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.70e-1)" "unprognostic (4.67e-2)" "unprognostic (2.68e-1)" "unprognostic (2.61e-2)" "unprognostic (4.52e-2)" "unprognostic (4.14e-2)" "unprognostic (5.85e-2)" "unprognostic (4.72e-2)" 4.0 0.6 0.8 14.4 1.0 71.8 1.8 1.1 0.9 1.4 0.2 3.9 5.5 1.6 1.1 3.0 2.0 4.3 2.8 0.9 1.4 0.8 2.6 28.3 26.3 3.5 1.3 0.6 1.0 0.6 0.2 0.9 2.5 1.3 5.3 0.3 2.3 1.1 0.8 2.8 6.3 2.3 1.8 19.0 5.0 0.4 2.5 51.1 0.8 0.3 23.0 4.2 0.5 4.1 0.2 0.2 0.1 0.3 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.9 0.1 0.6 1.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 278.8 0.2 2.0 0.0 281.5 158.3 0.0 0.0 0.1 0.0 0.1 0.0 68.0 96.1 76.9 0.5 0.2 122.2 70.1 0.1 0.0 0.0 98.4 1.1 2.2 0.0 0.0 0.2 0.1 0.2 0.3 0.1 0.3 0.1 164.1 0.4 0.0 0.2 0.2 0.2 0.3 5.8 40.7 0.3 205.4 0.3 13.6 23.2 14.6 96.3 96.3 51.4 3.7 38.5 65.5 34.0 1.1 26.3 47.6 3.6 69.4 218.0 27.2 34.7 52.1 0.8 1.0 1.1 0.9 0.9 1.4 3.5 1.3 2.5 1.8 2.5 4.1 1.2 9.6 16.9 0.0 10.8 2.2 0.9 0.0 0.0 0.6 1.0 0.8 5.3 1.5 2.5 1.8 0.0 0.2 131.6 0.1 0.0 0.1 0.1 0.5 0.6 3.0 0.0 125.9 0.0 0.0 0.4 3.0 5.1 0.7 43.7 0.8 4.6 1.5 27.0 1.7 0.0 0.3 0.0 28.8 30.3 0.0 0.0 65.8 1.8 1.9 66.4 0.5 352.2 1.5 0.0 0.0 0.1 0.0 60.3 0.5 0.1 0.6 1.5 1.9 0.0 0.8 1.0 0.2 0.6 0.1 2.0 0.3 94.8 0.1 0.2 0.6 SPNS2 SLC62A2 ENSG00000183018 "Sphingolipid transporter 2" Q8IVW8 17 4498881-4539035 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.0" "Cell type enhanced" "Detected in many" "Adipocytes: 32.7;Endothelial cells: 34.5;Microglial cells: 37.5;Oligodendrocytes: 97.8;Urothelial cells: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 31.0;RPTEC TERT1: 161.7;SK-BR-3: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068717 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA068717: AB_2686021" "unprognostic (3.03e-2)" "unprognostic (4.76e-2)" "unprognostic (8.08e-2)" "unprognostic (3.53e-2)" "unprognostic (2.78e-1)" "unprognostic (6.30e-3)" "unprognostic (1.10e-3)" "unprognostic (2.33e-1)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.99e-2)" "unprognostic (2.98e-2)" "unprognostic (4.48e-2)" "unprognostic (2.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.19e-2)" "unprognostic (6.89e-2)" 17.3 2.6 13.1 5.2 14.0 7.9 14.7 13.1 18.2 14.6 0.1 6.5 12.2 8.6 0.6 51.0 7.8 12.1 10.7 14.1 12.1 28.6 3.8 28.3 4.9 26.4 16.2 1.8 10.0 1.1 2.1 7.9 28.9 5.3 2.1 0.6 16.5 2.0 4.4 24.8 10.8 4.8 13.9 11.4 21.0 1.3 15.5 1.7 8.5 3.9 13.3 6.6 22.6 25.1 9.7 1.2 0.0 0.2 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.5 8.1 0.5 11.8 0.0 0.1 0.5 0.0 0.7 0.0 0.1 0.2 0.6 0.2 0.0 0.1 3.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 4.7 0.0 0.0 0.0 3.8 0.2 17.0 0.1 17.6 0.3 0.8 0.0 0.3 161.7 0.5 5.4 0.2 0.0 76.7 0.0 5.1 2.7 7.5 0.2 0.2 0.7 0.3 0.1 0.3 0.3 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.1 14.0 13.1 18.2 14.1 12.1 26.4 16.2 28.9 13.9 15.5 25.1 32.7 6.4 10.6 1.6 0.2 1.8 0.4 2.1 0.0 1.2 4.3 3.6 1.2 22.8 16.2 22.0 0.0 1.3 0.2 2.8 1.9 16.7 0.2 0.5 1.0 34.5 0.0 3.2 23.4 3.0 30.5 1.7 26.0 2.8 0.0 0.0 12.5 6.7 1.1 6.7 26.2 12.7 2.0 0.3 1.6 0.2 0.6 1.9 1.8 37.5 0.0 0.4 0.0 3.5 97.8 18.6 0.0 0.4 1.2 11.7 1.9 24.3 16.9 1.1 0.0 1.4 3.1 0.6 0.5 0.6 2.4 1.9 1.6 0.1 1.1 39.8 SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" 20.9 14.9 25.3 11.9 28.1 20.9 24.2 29.0 27.5 30.0 13.1 26.7 18.2 26.3 15.7 44.3 28.6 18.7 18.1 25.4 30.6 22.8 19.3 20.4 15.9 25.0 26.0 31.4 21.3 49.6 13.9 28.4 26.1 20.6 27.2 15.5 20.2 27.0 15.7 56.5 18.8 29.6 24.1 24.3 15.2 39.0 26.4 32.7 31.2 19.6 27.8 28.6 34.2 31.4 30.0 29.2 43.4 27.4 56.2 37.7 30.5 22.5 66.6 47.4 37.9 30.5 29.9 27.4 0.1 39.4 42.0 35.6 44.8 48.4 48.9 21.9 27.5 23.6 16.2 23.4 59.2 27.4 29.3 38.1 75.9 40.7 38.1 56.0 47.1 41.5 26.5 13.4 41.2 26.3 36.7 22.0 29.2 27.8 20.6 21.6 36.6 19.7 36.8 83.8 29.7 31.9 42.8 19.6 34.7 46.1 58.9 18.7 35.4 21.9 29.5 13.6 17.1 30.9 60.3 26.4 32.5 22.3 36.9 4.8 1.2 1.1 1.3 1.2 1.8 1.3 1.6 1.7 2.1 1.6 1.5 1.7 2.2 1.3 1.1 2.7 1.4 0.7 25.3 28.1 29.0 27.5 25.4 30.6 25.0 26.0 26.1 24.1 26.4 31.4 35.2 19.2 20.8 79.3 25.3 55.1 32.3 29.4 43.3 37.8 35.2 24.1 21.2 20.0 19.8 40.5 27.1 42.0 21.2 47.2 1.9 19.3 8.6 20.9 26.9 33.0 27.1 14.5 97.2 24.7 29.0 33.2 25.0 29.7 4.5 68.7 37.5 33.1 38.3 37.0 112.6 33.7 22.4 38.1 39.3 8.0 28.6 34.5 26.6 79.6 26.6 23.0 16.5 141.3 192.3 22.8 34.9 35.0 22.0 33.4 34.0 18.1 18.1 22.4 13.1 32.3 27.4 55.6 41.1 76.9 84.7 64.6 22.4 35.0 35.4 37.6 SPRR5 ENSG00000283227 "Small proline rich protein 5" A0A1B0GTR4 1 152947154-152949258 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "skin 1: 115.2" "Cell type enhanced" "Detected in single" "Exocrine glandular cells: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HaCaT: 2.0;hTCEpi: 5.3" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 115.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPTBN2 SCA5 ENSG00000173898 "Spectrin beta, non-erythrocytic 2" O15020 11 66682497-66729226 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6;skin 1: 85.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;Cone photoreceptor cells: 104.3;Early spermatids: 30.9;Late spermatids: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 45.6;NTERA-2: 49.1;SCLC-21H: 49.9;SK-BR-3: 52.3;T-47d: 67.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009844, HPA039293, HPA043529" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Vesicles "CAB009844: AB_2194521, HPA039293: AB_2676430, HPA043529: AB_2678531" "unprognostic (9.34e-2)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (3.41e-3)" "unprognostic (4.91e-1)" "unprognostic (6.05e-3)" "unprognostic (4.45e-2)" "unprognostic (1.38e-2)" "unprognostic (7.25e-2)" "unprognostic (1.67e-2)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.64e-1)" "unprognostic (1.05e-3)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" "unprognostic (3.99e-2)" "unprognostic (1.00e-3)" 1.3 14.4 26.8 1.0 32.6 2.3 7.7 29.7 73.6 14.3 0.0 0.9 0.9 1.7 1.2 39.8 3.7 1.7 1.4 38.8 0.3 37.5 23.3 1.1 0.2 4.8 0.9 0.9 16.7 13.1 16.4 0.4 3.2 12.4 0.7 14.7 29.6 4.7 0.5 85.5 1.0 1.1 0.0 0.9 2.9 52.8 4.6 1.0 0.3 0.1 6.7 1.6 16.5 24.2 20.5 7.4 3.4 0.3 0.1 0.0 0.6 0.3 0.1 0.1 0.0 4.8 28.2 0.2 3.7 0.0 0.7 16.9 25.2 2.4 0.0 0.1 10.4 0.1 45.6 3.0 0.8 7.3 0.6 0.2 11.5 0.0 7.4 4.2 6.3 5.2 7.3 0.1 0.1 35.2 6.3 3.5 49.1 28.7 21.1 23.8 2.8 14.7 9.6 4.8 49.9 29.4 14.0 52.3 3.2 2.7 67.2 2.4 1.4 0.1 8.6 1.3 11.5 0.7 3.0 14.7 0.1 0.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 26.8 32.6 29.7 73.6 38.8 0.3 4.8 0.9 3.2 0.0 4.6 24.2 0.7 3.2 1.1 4.9 0.3 3.7 2.7 3.2 2.8 11.0 4.7 4.6 1.8 1.5 4.6 86.5 104.3 0.9 0.0 0.6 0.0 2.6 30.9 3.6 1.8 1.1 3.0 7.2 29.3 10.0 0.3 0.8 1.5 3.6 0.0 1.4 1.4 24.7 0.1 0.0 20.7 1.6 0.0 0.3 0.7 77.6 1.8 0.1 0.0 2.8 0.6 1.6 0.0 7.5 4.6 7.5 0.2 1.5 0.8 3.2 0.2 1.3 3.5 21.3 0.0 0.2 0.5 8.5 9.4 14.6 12.5 0.3 0.2 0.1 0.8 1.7 SPTBN5 "BSPECV, HUBSPECV, HUSPECV" ENSG00000137877 "Spectrin beta, non-erythrocytic 5" Q9NRC6 15 41848146-41894053 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 8.8;retina: 26.9" "Group enriched" "Detected in many" 22 "Cone photoreceptor cells: 210.6;Rod photoreceptor cells: 211.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.7;SCLC-21H: 5.1;TIME: 13.6;WM-115: 4.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "spinal cord: 3.6" HPA055283 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA055283: " "unprognostic (5.46e-2)" "unprognostic (2.49e-1)" "unprognostic (3.28e-2)" "unprognostic (2.01e-1)" "unprognostic (2.26e-2)" "unprognostic (5.84e-3)" "unprognostic (1.12e-1)" "unprognostic (6.84e-3)" "unprognostic (6.40e-3)" "unprognostic (2.25e-1)" "unprognostic (2.96e-2)" "unprognostic (6.92e-2)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.28e-1)" "unprognostic (1.37e-2)" "unprognostic (1.11e-2)" 1.0 0.3 0.4 0.7 1.3 0.4 1.1 8.8 1.4 0.6 0.1 0.5 0.3 0.4 0.8 1.7 0.5 0.9 2.0 0.6 0.1 1.7 1.6 1.2 0.6 0.8 0.3 0.6 1.1 0.5 1.9 0.2 1.0 1.6 0.2 26.9 2.7 0.3 0.4 1.7 0.5 0.2 0.1 0.5 1.0 0.8 0.1 0.0 2.1 0.4 0.1 2.6 0.7 0.8 0.2 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.6 0.0 0.8 0.0 1.5 0.4 0.0 0.2 0.0 0.8 0.1 0.0 1.6 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.3 0.0 0.3 1.4 5.1 0.1 0.2 0.4 0.1 0.4 0.8 0.0 13.6 0.0 1.3 0.3 1.7 1.5 2.3 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 8.8 1.4 0.6 0.1 0.8 0.3 1.0 0.1 0.1 0.8 1.9 0.0 2.4 2.9 0.2 0.8 0.9 0.4 1.2 7.9 1.8 2.0 4.0 0.0 1.5 0.0 210.6 0.1 0.8 0.7 0.0 0.5 1.1 1.1 0.3 3.7 0.0 0.0 2.3 0.2 0.3 0.6 2.0 3.8 1.3 1.0 0.4 0.5 2.0 3.3 0.5 0.5 0.0 0.0 0.6 0.9 0.0 1.0 1.8 0.0 0.8 9.6 1.0 6.0 0.5 1.0 1.4 0.0 0.9 0.2 0.2 0.6 0.8 211.8 0.0 0.2 0.3 0.5 0.5 3.9 1.3 0.0 0.5 0.2 0.6 1.0 SPTLC3 "C20orf38, FLJ11112, hLCB2b, LCB2B, SPTLC2L" ENSG00000172296 "Serine palmitoyltransferase long chain base subunit 3" Q9NUV7 20 13008972-13169103 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.4;Early spermatids: 27.9;Glandular and luminal cells: 47.4;Microglial cells: 35.6;Syncytiotrophoblasts: 46.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 33.3;RPTEC TERT1: 43.7;U-2197: 30.4;U-87 MG: 57.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA044247, HPA048079" Enhanced Approved Microtubules NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" Microtubules "HPA044247: AB_2678872, HPA048079: AB_2680252" "unprognostic (6.81e-2)" "unprognostic (7.76e-2)" "unprognostic (4.46e-2)" "unprognostic (1.25e-3)" "unprognostic (5.43e-2)" "unprognostic (2.12e-1)" "unprognostic (5.70e-2)" "unprognostic (7.99e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (5.08e-2)" "prognostic favorable (4.51e-7)" "unprognostic (2.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.18e-1)" 4.6 4.3 1.4 1.4 1.4 0.6 8.3 1.2 1.3 7.4 8.5 6.1 15.7 4.7 16.8 5.9 6.7 10.9 6.4 1.5 2.7 18.2 20.0 7.8 1.3 2.4 2.1 7.1 5.6 11.0 2.7 20.9 2.4 5.9 7.4 2.8 6.7 3.6 0.4 25.6 16.2 3.9 1.8 2.9 4.5 6.4 3.8 5.0 24.4 2.0 1.7 5.7 5.1 2.5 1.5 2.4 1.8 0.0 14.1 20.2 11.4 0.0 3.2 2.1 8.2 18.6 9.3 0.0 1.2 0.6 18.2 25.0 0.0 7.0 3.0 0.0 0.1 0.0 5.6 26.4 1.3 0.0 0.2 11.5 21.4 8.4 2.8 7.7 1.4 4.4 0.0 33.3 23.7 0.5 0.1 0.0 0.1 2.2 2.9 2.3 4.2 15.1 43.7 18.2 0.0 0.3 0.2 2.3 0.1 3.1 18.6 0.5 3.3 9.2 3.1 30.4 2.2 0.2 0.0 0.0 57.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.4 1.4 1.2 1.3 1.5 2.7 2.4 2.1 2.4 1.8 3.8 2.5 3.6 6.4 22.3 5.2 0.1 2.4 5.3 2.3 4.6 0.1 5.4 5.0 17.9 4.3 4.9 9.2 0.0 28.4 1.0 3.4 7.9 3.0 27.9 18.7 5.2 4.6 0.0 2.1 0.5 4.4 13.0 5.4 4.6 47.4 1.3 5.6 1.8 20.7 2.8 0.0 0.9 5.7 6.1 2.6 0.4 11.6 3.7 2.4 0.0 35.6 0.0 12.3 3.1 0.0 0.1 3.2 6.7 2.6 0.1 2.3 10.9 18.6 3.5 0.4 0.0 6.1 0.8 1.2 0.1 4.9 2.3 46.1 1.2 2.9 7.3 2.6 SPX "C12orf39, MGC10946, NPQ, spexin" ENSG00000134548 "Spexin hormone" Q9BT56 12 21526296-21541249 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 111.4" "Group enriched" "Detected in some" 4 "Distal tubular cells: 86.1;Proximal tubular cells: 202.2" "Cancer enriched" "Detected in many" 5 "renal cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 17.5;HBEC3-KT: 8.9;hTERT-HME1: 12.4;SuSa: 14.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 17.1;hippocampal formation: 17.9;olfactory bulb: 7.5;pons: 8.0" "Secreted to blood" NA NA 2650000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.78e-2)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (1.81e-2)" "unprognostic (2.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (5.89e-2)" "unprognostic (1.21e-2)" "unprognostic (1.95e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.37e-3)" "unprognostic (9.78e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" 111.4 0.1 8.7 0.1 9.2 0.4 4.1 8.6 24.2 0.0 7.2 0.1 0.0 1.3 0.6 0.2 0.2 0.1 2.8 8.1 11.5 26.4 2.3 0.6 0.2 8.6 13.9 0.0 20.7 0.4 0.0 17.7 26.6 0.0 0.0 1.7 6.9 0.5 2.0 0.0 0.3 0.1 8.0 0.4 0.5 0.2 9.6 3.0 20.2 8.8 0.1 0.0 0.0 9.9 0.0 0.5 0.8 0.0 3.0 1.2 0.0 0.0 0.1 0.1 1.2 17.5 0.0 0.7 0.3 0.0 0.3 0.0 0.0 8.9 1.6 0.0 0.0 4.7 0.0 0.1 1.8 0.0 0.0 5.7 0.9 0.3 12.4 0.2 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.0 1.1 0.0 0.7 0.0 2.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 1.7 14.6 0.0 0.2 0.3 0.0 5.3 0.0 0.4 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.7 9.2 8.6 24.2 8.1 11.5 8.6 13.9 26.6 8.0 9.6 9.9 1.4 0.0 0.0 1.3 1.3 0.0 0.1 0.0 0.0 3.0 0.7 0.9 28.9 0.0 0.0 25.8 0.0 0.0 0.1 0.0 86.1 0.4 0.0 0.5 0.3 0.6 0.0 0.0 0.0 19.1 0.0 1.7 0.0 2.5 0.0 0.0 0.7 0.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 13.7 0.0 0.0 1.2 4.9 4.1 0.0 0.1 2.5 0.0 0.0 0.0 0.1 0.0 202.2 0.0 0.5 0.0 2.4 0.9 0.0 1.8 0.0 0.0 0.4 1.0 0.1 0.0 0.1 SRD5A1 ENSG00000145545 "Steroid 5 alpha-reductase 1" P18405 5 6633427-6674386 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 29.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 67.2;Hepatocytes: 103.4;Ionocytes: 52.9;Squamous epithelial cells: 139.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051402 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA051402: AB_2681470" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (2.30e-3)" "prognostic unfavorable (8.73e-6)" "unprognostic (9.38e-3)" "unprognostic (8.90e-2)" "unprognostic (3.78e-2)" "unprognostic (5.90e-2)" "unprognostic (3.83e-1)" "unprognostic (1.42e-1)" "unprognostic (7.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.56e-3)" "unprognostic (3.01e-1)" "unprognostic (2.24e-1)" "unprognostic (1.59e-1)" "unprognostic (5.47e-2)" 1.5 2.0 4.7 1.9 5.3 2.2 11.0 7.4 8.8 3.9 0.1 2.4 4.1 1.7 3.0 11.0 1.7 1.7 1.0 5.5 3.2 4.6 29.0 1.9 2.3 6.0 3.3 2.5 2.3 1.4 1.1 1.0 6.3 1.5 2.3 3.8 2.7 1.1 1.3 13.6 4.1 1.6 1.8 1.4 2.5 1.5 6.9 1.6 1.3 0.7 4.1 1.1 6.6 8.3 5.2 6.1 8.0 6.7 7.6 7.3 3.5 5.7 4.5 5.7 3.5 6.0 5.3 7.1 8.1 8.7 9.1 9.8 6.6 4.0 6.0 4.3 2.6 2.2 15.3 3.7 3.4 3.3 1.8 5.4 11.3 4.1 3.2 4.2 2.9 2.7 3.7 6.2 7.5 7.1 1.4 3.6 4.5 4.1 4.7 5.1 5.8 2.0 7.6 5.4 14.0 6.4 18.2 7.6 5.8 6.1 2.6 0.9 5.8 8.6 3.4 14.2 7.6 2.3 3.6 2.6 7.2 3.6 8.0 3.5 1.3 0.5 0.3 1.0 0.2 0.5 0.3 0.5 1.6 0.6 0.2 0.3 0.7 0.5 1.1 0.7 0.4 0.5 4.7 5.3 7.4 8.8 5.5 3.2 6.0 3.3 6.3 1.8 6.9 8.3 3.7 3.2 2.7 7.8 11.9 18.5 6.7 19.0 67.2 5.0 14.5 9.1 2.6 11.5 12.8 5.5 4.2 0.9 5.0 8.3 7.9 9.8 8.1 2.6 4.3 3.2 2.4 4.4 15.5 4.7 7.4 4.7 16.3 3.2 1.3 6.0 4.6 103.4 13.0 6.7 14.9 7.2 52.9 19.4 11.6 2.6 3.4 11.6 7.2 6.5 50.7 5.1 10.3 9.0 7.6 6.7 10.4 7.9 7.2 9.4 24.9 23.4 10.4 3.8 0.0 3.7 6.1 3.4 4.4 139.2 30.4 0.8 5.9 5.2 12.0 10.2 SRGAP2B SRGAP2P2 ENSG00000196369 "SLIT-ROBO Rho GTPase activating protein 2B" P0DMP2 1 144887265-145095528 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.7" "Cell type enriched" "Detected in many" 4 "Microglial cells: 239.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 3.6;granulocytes: 3.9;monocytes: 7.9" "Low cell line specificity" "Detected in all" HPA078079 Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" Cytosol "HPA078079: " "unprognostic (1.13e-2)" "unprognostic (2.76e-1)" "unprognostic (1.48e-3)" "unprognostic (3.52e-3)" "unprognostic (1.66e-2)" "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (4.60e-2)" "unprognostic (3.13e-1)" "unprognostic (2.89e-2)" "unprognostic (7.27e-2)" "unprognostic (1.88e-1)" "unprognostic (2.16e-5)" "unprognostic (3.12e-1)" "unprognostic (5.43e-1)" "unprognostic (8.54e-2)" "unprognostic (2.38e-1)" 9.3 10.5 9.9 6.8 9.2 7.7 6.1 48.7 10.3 6.3 3.7 4.7 2.8 6.2 4.2 5.7 6.7 5.7 5.1 10.3 10.5 8.0 4.2 8.6 5.6 15.4 14.4 8.6 3.6 13.1 3.0 10.8 19.4 3.7 2.8 3.7 3.3 4.6 8.9 18.9 3.5 7.1 14.9 12.4 2.9 3.5 12.4 6.4 4.3 5.8 3.7 5.0 6.4 17.1 13.4 28.5 60.3 12.5 28.3 24.3 19.0 14.6 12.8 12.2 14.0 8.7 24.1 6.7 19.1 8.7 21.7 22.8 15.6 8.5 15.0 6.3 15.8 9.8 20.6 12.1 19.8 8.8 12.5 17.3 12.6 30.1 26.4 18.4 24.8 5.7 5.3 23.1 6.7 15.1 3.8 10.3 11.2 6.7 10.2 10.3 12.9 11.6 10.5 5.8 7.5 9.5 19.3 6.9 31.6 14.9 14.4 22.1 45.3 26.1 26.7 23.3 17.1 9.6 12.7 4.1 9.5 11.6 37.7 1.2 3.8 0.5 0.6 5.4 0.5 0.9 1.0 1.2 2.7 0.9 0.6 0.7 3.9 0.4 7.9 3.6 1.1 0.9 9.9 9.2 48.7 10.3 10.3 10.5 15.4 14.4 19.4 14.9 12.4 17.1 37.3 25.6 7.7 5.5 14.0 0.0 3.5 0.0 6.8 17.6 3.1 3.4 3.3 5.7 2.5 9.2 2.1 4.7 20.3 0.5 0.0 6.8 1.1 13.8 14.0 35.1 2.4 29.3 37.5 3.0 21.5 15.3 3.1 6.0 1.3 3.3 54.3 4.3 12.9 0.0 55.6 2.0 0.0 58.7 0.0 2.7 15.2 40.1 0.0 239.8 38.4 8.1 16.5 24.6 9.5 6.0 0.2 9.8 8.4 4.8 0.8 1.2 8.0 2.9 6.6 16.9 12.3 4.5 6.9 19.9 0.0 2.9 6.9 8.6 1.8 4.2 SRGAP2C SRGAP2P1 ENSG00000171943 "SLIT-ROBO Rho GTPase activating protein 2C" P0DJJ0 1 121184811-121392874 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.2" "Cell type enhanced" "Detected in many" "Microglial cells: 180.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "WM-115: 80.0" HPA078079 Approved Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Cytosol "HPA078079: " "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (7.65e-3)" "unprognostic (1.48e-6)" "unprognostic (2.40e-2)" "unprognostic (1.11e-1)" "unprognostic (7.18e-4)" "unprognostic (6.10e-2)" "unprognostic (7.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.36e-2)" "unprognostic (2.89e-1)" "unprognostic (3.71e-7)" "unprognostic (4.90e-2)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" "unprognostic (7.66e-2)" 8.3 6.5 11.1 3.7 13.2 7.2 5.7 31.2 12.5 5.8 3.9 6.5 2.1 5.4 2.2 4.3 5.0 4.6 5.8 11.7 11.8 7.1 4.7 7.3 4.6 16.1 12.3 6.8 2.2 13.7 3.3 8.0 17.6 3.6 2.8 3.5 3.0 4.6 2.8 15.5 3.6 6.0 16.6 10.7 3.2 1.5 12.4 4.2 3.9 10.7 3.4 4.6 5.5 21.9 11.1 14.1 30.7 6.8 23.1 20.1 16.8 12.3 9.8 10.2 13.2 0.2 11.0 7.0 10.8 16.8 7.3 5.9 11.0 8.9 13.4 9.2 11.2 10.0 24.5 11.1 13.3 6.8 11.4 15.2 8.9 13.1 16.6 11.6 24.5 4.3 9.3 12.8 7.6 6.6 4.3 8.6 9.7 3.5 6.7 6.2 35.9 6.2 9.7 6.5 5.9 3.8 21.2 7.5 38.6 15.8 9.5 19.8 21.9 19.1 18.7 28.9 18.1 7.3 5.6 4.2 16.7 13.7 80.0 0.3 3.4 0.6 1.1 2.8 0.7 0.9 1.3 1.2 2.5 0.9 0.6 0.8 3.2 0.6 5.3 2.4 1.3 0.9 11.1 13.2 31.2 12.5 11.7 11.8 16.1 12.3 17.6 16.6 12.4 21.9 39.9 54.5 11.5 5.2 14.4 0.0 5.6 0.0 6.2 14.2 5.8 6.7 4.3 15.7 5.0 11.0 2.1 5.5 15.5 1.2 1.9 10.9 1.0 11.7 15.4 34.6 2.4 29.7 42.0 5.0 24.8 15.9 5.1 6.4 6.3 7.8 55.3 8.7 19.9 0.0 62.6 2.7 0.0 64.2 0.0 2.1 19.6 41.6 0.0 180.8 39.6 8.4 18.6 35.2 27.4 7.2 1.4 25.6 10.7 5.0 0.5 1.0 8.7 4.3 32.9 20.2 14.5 10.1 10.8 12.5 0.0 2.5 12.6 7.0 2.0 4.5 SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63540810-63547504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 1.6" "Cell type enriched" "Detected in single" 4 "Gastric mucus-secreting cells: 3.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.3;MCF7: 3.0;OE19: 4.4;RT4: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: AB_10609403, CAB044669: AB_10608235, HPA073987: AB_2686650" "unprognostic (2.26e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-3)" "unprognostic (8.32e-2)" "unprognostic (2.62e-1)" "unprognostic (5.47e-3)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (9.63e-2)" "unprognostic (6.48e-3)" "unprognostic (7.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.73e-3)" "unprognostic (2.58e-3)" "unprognostic (4.75e-2)" "unprognostic (4.97e-2)" "unprognostic (2.54e-3)" 0.0 0.0 0.1 0.2 0.1 0.1 0.4 0.6 0.2 0.0 0.0 0.7 0.2 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.8 0.0 0.0 0.4 0.2 0.0 0.1 0.9 1.6 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 1.3 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.1 0.0 4.4 0.4 0.0 0.1 0.0 0.0 6.0 0.4 0.5 0.1 1.2 0.2 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SRP68 ENSG00000167881 "Signal recognition particle 68" Q9UHB9 17 76038775-76072517 "Plasma proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 314.6" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 162.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "medulla oblongata: 314.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023303, HPA055617" Approved Supported Cytosol NA NA 23000 "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA023303: AB_1857477, HPA055617: AB_2682863" "unprognostic (1.25e-1)" "unprognostic (8.97e-2)" "unprognostic (3.47e-2)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.18e-4)" "prognostic unfavorable (4.28e-5)" "unprognostic (3.31e-2)" "unprognostic (8.31e-2)" "unprognostic (1.62e-2)" "unprognostic (1.11e-1)" "unprognostic (4.10e-2)" "unprognostic (4.42e-2)" "unprognostic (8.73e-2)" "unprognostic (4.75e-2)" "prognostic favorable (2.65e-4)" "unprognostic (4.02e-3)" 37.5 34.6 23.7 24.8 25.2 21.9 36.3 25.5 76.6 39.4 24.6 47.2 21.3 39.7 35.1 49.8 37.4 17.3 42.8 34.8 27.7 31.6 37.0 34.0 29.0 314.6 25.1 39.8 65.7 37.7 37.7 33.1 49.6 30.6 27.4 28.0 38.5 26.1 103.1 43.7 32.2 34.5 30.5 31.5 41.5 22.2 25.9 30.8 32.8 47.0 36.7 41.9 37.9 26.4 98.0 89.8 51.0 54.9 71.5 57.2 94.3 72.4 50.7 80.7 62.9 75.5 45.5 81.6 36.8 70.5 69.2 66.2 98.2 74.2 119.2 34.3 118.1 72.6 63.4 102.8 86.3 83.9 54.7 48.5 81.3 70.7 61.1 60.0 95.1 47.4 109.0 70.9 67.2 60.1 84.6 43.5 50.3 81.2 91.0 70.1 137.1 79.9 59.2 80.6 63.2 64.9 61.9 103.8 81.8 85.2 91.5 76.4 62.3 89.2 70.7 42.7 99.4 70.5 34.7 87.1 64.0 62.2 66.4 7.6 28.6 37.3 24.5 26.3 26.4 30.5 34.8 37.9 34.3 25.3 39.2 29.4 4.3 45.4 27.1 27.1 34.6 19.4 23.7 25.2 25.5 76.6 34.8 27.7 314.6 25.1 49.6 30.5 25.9 26.4 20.9 28.9 22.9 12.1 27.9 31.4 49.3 30.2 22.2 24.2 18.2 19.2 27.2 28.6 25.9 12.9 37.5 86.9 21.2 18.3 37.2 43.6 15.0 24.3 26.1 28.1 14.4 41.3 11.1 41.4 63.2 26.8 16.8 28.5 17.1 25.6 21.8 23.2 37.9 37.0 10.8 22.8 20.3 18.5 17.4 20.0 24.2 17.8 24.9 11.2 31.8 36.8 29.9 7.1 11.5 39.0 15.8 28.2 37.9 46.5 20.7 30.4 23.7 26.7 0.0 28.5 31.7 47.2 24.4 26.6 31.7 162.3 25.2 30.2 24.1 48.9 SST SMST ENSG00000157005 Somatostatin P61278 3 187668912-187670394 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 449.5;intestine: 386.6;pancreas: 479.4;stomach 1: 418.0" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 1404.1;Intestinal goblet cells: 460.2" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 1039.3" "Region enhanced" "Detected in all" "hypothalamus: 449.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 22.4;U-2 OS: 44.7;U-251 MG: 7.6;U-698: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000075, HPA019472, CAB034105" Enhanced Supported "Secreted to blood" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB000075: AB_2688022, CAB034105: AB_2271061, HPA019472: AB_1857360" "unprognostic (2.44e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.12e-3)" "unprognostic (1.54e-2)" "unprognostic (4.69e-1)" "unprognostic (3.31e-2)" "unprognostic (8.16e-3)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (8.47e-2)" "unprognostic (4.19e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" 5.5 43.0 59.9 4.6 52.1 4.2 0.5 1.3 67.8 0.6 2.5 31.8 386.6 0.7 0.1 1.6 0.4 1.1 1.3 30.6 449.5 6.2 0.3 0.3 1.5 96.9 48.1 2.4 479.4 0.0 9.3 0.1 50.3 1.3 23.8 6.3 0.1 21.6 0.1 8.9 133.3 2.8 137.8 0.2 418.0 0.2 117.2 1.1 1.0 0.0 0.0 7.3 1.8 18.7 0.0 0.0 0.8 0.1 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.5 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 44.7 0.4 7.6 0.0 2.9 11.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.9 52.1 1.3 67.8 30.6 449.5 96.9 48.1 50.3 137.8 117.2 18.7 0.0 0.0 0.0 9.1 0.5 0.0 0.0 3.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 5.5 0.0 0.1 0.0 4.3 0.0 0.0 0.3 0.3 0.5 0.1 1404.1 0.0 1.7 0.0 0.2 0.7 0.0 4.2 0.0 0.0 0.0 0.0 0.3 0.0 146.2 460.2 215.7 0.0 0.0 0.1 0.0 0.0 0.0 9.4 3.6 0.0 0.0 3.0 9.1 0.0 0.6 0.0 0.0 0.0 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.9 13.8 0.2 ST6GAL1 SIAT1 ENSG00000073849 "ST6 beta-galactoside alpha-2,6-sialyltransferase 1" P15907 3 186930325-187078553 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 495.9;lymphoid tissue: 148.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 237.3;Hepatic stellate cells: 258.5;Hepatocytes: 608.7;Microglial cells: 602.4" "Cancer enhanced" "Detected in all" "liver cancer: 70.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 250.6;U-266/70: 628.0;U-266/84: 887.9;U-698: 334.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015018, CAB016122" Supported "Secreted to blood" NA NA 15000000 3300000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" "CAB015018: AB_629203, CAB016122: AB_627178" "unprognostic (5.85e-3)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (2.64e-1)" "unprognostic (2.44e-2)" "unprognostic (1.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (3.99e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" "unprognostic (7.30e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-2)" 24.5 12.5 27.0 50.2 26.2 15.2 32.5 29.8 24.8 61.4 33.3 38.1 13.9 16.1 5.9 13.5 27.0 17.8 36.0 25.8 33.9 60.0 495.9 30.1 101.7 44.0 37.5 10.1 8.1 45.5 9.8 18.5 50.3 48.8 45.4 2.6 39.3 14.6 12.8 8.3 29.1 18.9 44.1 67.5 28.8 3.5 39.2 66.6 64.8 20.2 148.1 28.0 8.9 48.3 4.3 5.0 20.6 17.1 1.1 0.0 36.3 1.6 3.0 1.4 2.0 1.9 2.0 250.6 19.5 0.1 8.8 10.1 132.7 15.4 1.6 11.3 7.4 10.1 0.8 119.0 1.3 22.8 75.0 1.7 28.3 0.0 11.5 19.9 77.5 24.2 52.2 20.3 5.2 8.7 17.0 14.7 49.9 11.3 7.6 38.2 0.4 8.1 9.9 0.5 36.4 4.1 1.5 26.6 64.6 29.1 38.9 16.8 32.6 0.2 3.3 0.6 2.1 628.0 887.9 334.0 0.5 45.4 84.7 22.6 8.9 3.6 46.9 16.2 42.9 87.9 51.3 39.7 14.2 83.3 80.4 58.4 4.2 26.9 29.3 11.9 43.8 58.7 27.0 26.2 29.8 24.8 25.8 33.9 44.0 37.5 50.3 44.1 39.2 48.3 34.6 44.8 27.4 13.4 110.0 4.0 13.8 68.0 4.6 0.3 5.1 4.1 26.2 75.8 55.9 237.3 0.0 0.3 26.3 20.7 0.0 17.1 0.5 8.9 5.0 56.0 94.1 24.8 47.2 0.9 3.5 3.7 7.7 16.1 10.8 7.3 258.5 608.7 20.3 0.0 31.5 10.9 34.6 61.3 16.4 1.1 0.3 18.2 7.2 602.4 17.2 0.1 26.8 145.3 2.8 6.0 17.8 0.7 124.3 103.6 0.6 0.5 39.8 1.1 0.0 2.2 6.8 0.0 0.5 0.8 1.6 0.7 28.4 0.3 37.3 39.0 ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 912.5;Oligodendrocytes: 698.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 35.8;HUVEC TERT2: 45.9;SK-MEL-30: 62.3;TIME: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" 8.8 1.4 5.8 1.8 13.3 3.1 6.4 14.3 8.4 1.9 10.4 2.0 0.7 5.9 0.5 1.9 2.7 2.5 4.4 6.9 9.0 8.7 2.0 5.2 2.0 15.2 10.6 2.3 0.9 4.4 2.1 3.1 17.2 1.1 2.4 3.9 1.1 1.6 1.6 0.8 1.4 4.5 13.3 1.4 1.5 0.3 11.3 0.9 13.3 6.5 0.7 2.6 1.6 21.0 0.2 0.0 35.8 0.0 0.6 0.0 0.0 0.0 4.2 0.6 0.4 11.9 0.1 0.6 2.4 0.3 2.3 0.1 0.0 0.4 0.3 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.0 0.0 1.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 2.9 0.0 1.8 1.7 0.0 0.0 0.0 2.7 8.8 0.0 0.0 62.3 8.3 0.0 0.2 20.6 0.3 2.8 0.1 3.3 0.0 0.0 0.0 0.0 8.4 5.5 0.0 6.3 2.8 0.0 2.2 0.0 2.6 0.3 0.5 2.3 3.8 1.3 1.4 3.9 0.3 4.3 0.0 0.0 1.9 5.8 13.3 14.3 8.4 6.9 9.0 15.2 10.6 17.2 13.3 11.3 21.0 59.8 3.2 1.5 174.3 5.6 0.3 0.2 0.0 0.6 3.2 0.6 1.0 1.2 0.0 0.0 3.7 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.1 4.5 23.2 0.0 0.4 107.0 0.0 0.1 2.5 3.6 0.1 0.0 0.8 66.0 0.8 1.1 0.0 101.4 0.5 0.0 9.8 0.7 0.8 0.0 3.7 5.4 912.5 3.0 12.3 1.0 23.1 698.3 0.2 3.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.3 0.2 0.7 0.1 0.4 0.1 2.0 6.9 0.3 0.1 ST7L "FAM4B, FLJ20284, ST7R, STLR" ENSG00000007341 "Suppression of tumorigenicity 7 like" Q8TDW4 1 112523514-112620825 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 36.0" "Cell type enhanced" "Detected in all" "Early spermatids: 189.7;Late spermatids: 301.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042324, HPA075418" Uncertain Approved Centrosome NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Centrosome "HPA042324: AB_10794273, HPA075418: AB_2686749" "unprognostic (2.99e-2)" "unprognostic (1.07e-2)" "prognostic favorable (8.34e-5)" "prognostic unfavorable (8.96e-4)" "unprognostic (3.30e-2)" "unprognostic (1.32e-1)" "unprognostic (3.84e-6)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.16e-4)" "prognostic favorable (3.04e-5)" "unprognostic (2.98e-2)" "unprognostic (6.91e-2)" "unprognostic (5.72e-2)" "unprognostic (4.12e-3)" "unprognostic (3.68e-2)" "unprognostic (3.26e-2)" "unprognostic (3.27e-2)" 4.6 5.2 2.4 2.2 3.1 5.5 4.8 3.7 3.2 4.6 2.5 3.1 2.9 5.2 4.9 3.5 3.7 3.4 5.4 2.2 2.4 3.6 4.2 2.8 2.9 1.9 2.5 5.6 3.9 4.7 2.2 3.9 2.1 4.3 4.7 6.8 2.9 4.2 4.8 6.1 2.6 4.1 2.3 2.1 2.3 36.0 2.3 3.4 7.6 4.6 3.3 3.7 3.1 3.6 5.2 1.5 8.8 6.1 11.7 11.6 2.0 5.9 4.8 2.6 3.9 2.8 4.8 2.0 2.4 2.6 7.9 3.3 10.2 8.3 4.0 3.2 6.0 6.2 8.0 2.1 6.7 4.9 6.3 2.3 2.0 3.0 6.3 6.2 8.9 7.4 3.4 6.5 11.1 1.4 2.7 1.9 4.0 2.3 5.3 4.4 4.0 0.8 5.7 6.2 6.2 3.7 3.4 4.8 4.4 1.5 3.6 3.0 8.8 6.0 5.9 7.9 6.0 1.7 1.3 2.1 5.5 8.2 13.5 0.1 0.9 0.1 1.2 1.1 1.9 2.4 1.8 0.9 0.9 1.3 2.5 1.4 0.2 3.7 0.9 1.8 1.4 1.0 2.4 3.1 3.7 3.2 2.2 2.4 1.9 2.5 2.1 2.3 2.3 3.6 14.4 22.4 9.6 46.0 8.0 17.0 16.7 14.9 23.9 19.7 13.7 15.9 6.7 12.8 12.8 9.2 6.2 13.0 10.8 4.9 9.8 8.5 189.7 8.5 13.8 12.1 5.4 9.9 48.1 8.6 6.7 12.2 8.6 9.5 8.2 15.1 5.0 8.0 8.5 25.2 55.0 9.8 18.3 10.9 8.6 301.2 18.0 12.5 21.4 37.5 6.0 21.8 3.1 68.3 67.9 7.4 5.1 16.1 13.9 12.4 6.8 6.9 10.4 25.2 19.7 15.7 13.3 65.4 14.5 17.6 18.3 6.2 11.3 17.2 9.7 10.6 STAC2 24b2 ENSG00000141750 "SH3 and cysteine rich domain 2" Q6ZMT1 17 39210541-39225945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.5;breast: 56.2;retina: 120.9;skin 1: 53.1" "Cell type enriched" "Detected in many" 9 "Muller glia cells: 496.8" "Cancer enhanced" "Detected in many" "breast cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "GAMG: 9.8;HeLa: 32.5;U-87 MG: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA076925 Approved Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA076925: " "unprognostic (1.70e-3)" "unprognostic (1.05e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (4.05e-5)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.42e-1)" "unprognostic (8.66e-2)" "unprognostic (2.94e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (1.12e-2)" "unprognostic (5.16e-2)" "unprognostic (2.35e-3)" "unprognostic (2.05e-2)" "unprognostic (1.94e-1)" "unprognostic (3.54e-2)" "unprognostic (3.17e-1)" 2.2 0.5 11.2 0.2 24.6 0.0 56.2 10.3 59.5 8.5 2.2 0.9 0.1 5.2 10.7 0.5 4.8 0.0 2.5 14.5 22.4 14.2 0.0 0.8 0.0 30.9 18.3 2.4 0.2 0.1 1.6 0.2 30.7 5.1 0.1 120.9 15.1 23.5 0.3 53.1 0.6 0.8 5.4 0.1 0.4 0.2 5.4 0.0 0.1 0.6 0.0 0.5 2.6 34.2 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 9.8 0.0 3.9 0.0 0.0 0.0 0.5 0.0 32.5 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.4 0.3 3.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.2 24.6 10.3 59.5 14.5 22.4 30.9 18.3 30.7 5.4 5.4 34.2 0.6 3.2 5.8 2.0 0.7 0.4 1.0 0.2 0.0 13.3 52.7 45.3 2.7 0.0 2.5 3.7 10.4 0.1 1.8 0.1 5.9 0.0 0.2 0.3 3.9 1.7 0.0 0.0 19.0 0.0 0.2 1.9 0.0 0.3 0.0 0.2 0.0 0.0 0.1 18.5 16.6 0.0 16.2 0.6 1.5 0.0 2.8 0.8 42.7 3.7 0.0 496.8 2.1 1.0 1.0 0.0 0.0 0.0 0.1 0.5 0.0 0.3 1.5 17.5 0.0 0.2 1.4 0.2 1.0 0.0 1.7 0.3 1.2 0.1 0.1 0.2 STAP2 "BKS, STAP-2" ENSG00000178078 "Signal transducing adaptor family member 2" Q9UGK3 19 4324043-4342786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 91.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 294.5;Paneth cells: 343.4;Proximal enterocytes: 415.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 7.9" "Group enriched" "Detected in many" 6 "dendritic cells: 2.2;NK-cells: 7.9;T-cells: 2.5" "Cell line enhanced" "Detected in many" "A-431: 87.3;HaCaT: 70.3;MCF7: 104.3;RT4: 138.1" "Region enriched" "Detected in many" 13 "cerebellum: 20.5" "Low region specificity" "Detected in some" "HPA002375, HPA027761" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA002375: AB_1078285, HPA027761: AB_1845364" "unprognostic (1.42e-1)" "prognostic favorable (2.76e-4)" "unprognostic (3.52e-1)" "prognostic favorable (3.03e-5)" "unprognostic (4.35e-2)" "unprognostic (9.35e-3)" "unprognostic (4.52e-1)" "unprognostic (7.81e-2)" "unprognostic (3.43e-1)" "unprognostic (2.00e-2)" "unprognostic (1.93e-2)" "unprognostic (9.05e-2)" "unprognostic (1.43e-3)" "unprognostic (1.38e-2)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "prognostic favorable (4.13e-4)" 5.6 18.1 2.6 7.5 2.7 0.4 16.6 3.6 4.2 18.1 3.5 72.8 77.5 5.7 10.6 91.0 15.1 7.1 4.9 2.7 2.4 28.5 55.3 8.2 3.2 2.4 2.2 11.5 30.6 21.3 4.4 3.4 2.7 37.9 59.7 0.5 45.4 9.8 1.2 73.9 72.0 4.0 2.0 1.5 24.2 2.0 2.5 7.9 15.3 0.7 13.0 16.5 41.0 2.6 87.3 0.4 6.2 5.8 0.4 4.7 35.7 1.6 8.8 2.8 2.2 52.0 34.8 0.1 13.3 2.8 17.9 70.3 1.1 50.3 1.6 14.9 0.7 0.3 0.4 35.1 10.9 0.1 0.7 3.5 41.7 4.8 12.2 7.0 8.9 2.1 3.4 18.6 1.3 104.3 1.3 0.7 4.8 55.3 20.4 3.6 0.8 2.2 29.4 138.1 2.1 3.5 0.1 25.9 14.6 2.2 60.7 0.3 12.5 0.2 1.2 0.7 1.8 0.1 1.4 1.3 0.3 0.4 5.7 0.4 0.1 0.0 0.6 0.0 2.3 0.6 0.8 0.1 0.7 0.1 2.3 1.4 0.1 7.9 0.0 2.2 2.5 0.8 2.6 2.7 3.6 4.2 2.7 2.4 2.4 2.2 2.7 2.0 2.5 2.6 6.7 9.6 14.4 0.3 2.4 40.5 59.8 171.4 42.7 0.6 33.8 30.1 6.9 38.6 87.2 29.5 0.0 16.9 2.3 294.5 25.4 137.5 1.2 9.0 3.6 10.1 85.8 4.4 1.5 101.0 3.0 4.5 55.5 13.4 8.9 5.2 7.5 29.6 1.8 0.0 1.2 147.5 91.6 4.1 9.4 0.9 4.7 1.8 19.6 0.0 12.5 1.0 1.0 0.5 1.8 139.4 343.4 1.9 1.4 92.6 415.7 125.0 44.9 0.8 0.0 1.7 7.9 0.6 2.6 86.0 61.8 12.4 3.3 5.7 173.2 117.0 STAR STARD1 ENSG00000147465 "Steroidogenic acute regulatory protein" P49675 8 38142700-38150992 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Steroidogenesis, Transport" "Congenital adrenal hyperplasia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "adrenal gland: 5073.8" "Cell type enriched" "Detected in some" 44 "Theca cells: 2243.4" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.0;lung cancer: 0.8;ovarian cancer: 1.4;testis cancer: 3.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 2.4" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.4" "Cell line enriched" "Detected in some" 5 "K-562: 436.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023644, HPA027318, CAB032598" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "CAB032598: AB_2115937, HPA023644: AB_10598916, HPA027318: AB_10601574" "unprognostic (1.60e-4)" "unprognostic (3.20e-2)" "unprognostic (9.17e-2)" "unprognostic (3.28e-2)" "unprognostic (9.22e-2)" "unprognostic (1.32e-3)" "unprognostic (1.96e-2)" "unprognostic (2.12e-5)" "unprognostic (3.30e-2)" "unprognostic (2.36e-1)" "unprognostic (1.77e-3)" "unprognostic (6.65e-2)" "unprognostic (4.75e-9)" "unprognostic (1.58e-1)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (6.16e-2)" 1.7 5073.8 2.3 3.1 1.6 2.1 0.4 1.6 3.3 1.0 0.7 0.5 0.2 0.5 0.6 2.1 6.3 0.2 0.9 1.5 4.5 0.4 1.2 0.5 0.9 3.8 3.3 497.1 0.9 0.0 2.2 0.5 4.1 0.5 0.1 0.6 1.8 0.3 0.4 5.0 0.6 0.4 1.4 1.0 0.7 88.2 3.0 3.0 0.4 0.0 1.9 0.5 3.2 1.5 0.1 0.0 0.8 0.2 0.3 3.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.1 0.0 88.9 0.8 5.3 1.3 3.8 0.1 12.4 0.3 0.1 0.1 0.8 0.0 0.3 436.1 0.2 0.0 0.0 0.4 43.7 9.6 0.1 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.2 0.2 0.0 0.2 0.0 0.1 43.0 1.5 0.1 0.0 0.2 0.1 0.2 0.2 0.0 0.3 9.3 0.2 2.4 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.2 0.0 2.3 1.6 1.6 3.3 1.5 4.5 3.8 3.3 4.1 1.4 3.0 1.5 0.0 0.0 0.0 0.7 0.1 9.4 0.7 0.8 4.0 1.1 0.1 1.1 0.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 1.9 10.7 0.6 0.0 0.0 1.4 0.0 0.0 25.7 0.0 0.3 0.0 1.4 0.0 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.7 10.2 50.1 0.2 3.6 0.0 0.0 0.6 0.0 0.5 0.3 0.1 0.0 4.1 0.0 0.2 0.0 0.0 0.4 0.6 0.0 0.2 3.0 4.8 0.8 1.7 11.2 0.1 0.1 2243.4 0.0 0.1 STARD13 "ARHGAP37, DLC2, GT650, LINC00464" ENSG00000133121 "StAR related lipid transfer domain containing 13" Q9Y3M8 13 33103137-33350630 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Astrocytes: 212.5;Excitatory neurons: 120.7;Inhibitory neurons: 135.6;Microglial cells: 167.7;Oligodendrocyte precursor cells: 212.6;Oligodendrocytes: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 50.2;TIME: 36.0;WM-115: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039535, HPA058867" Supported NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA039535: AB_10965929, HPA058867: AB_2683839" "unprognostic (7.42e-2)" "unprognostic (6.71e-2)" "unprognostic (1.99e-1)" "unprognostic (4.99e-2)" "unprognostic (1.17e-2)" "unprognostic (1.47e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" "unprognostic (1.48e-1)" "unprognostic (7.13e-3)" "unprognostic (3.42e-2)" "unprognostic (4.66e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (5.29e-2)" 16.0 10.9 10.0 5.6 13.2 0.3 11.1 8.7 10.9 16.6 13.4 28.0 4.8 14.8 5.3 7.2 10.4 10.8 12.5 12.6 8.1 8.4 6.1 12.5 2.5 11.1 11.9 7.2 10.8 16.9 4.3 24.6 9.6 9.0 6.8 1.8 6.4 8.1 5.4 5.3 7.0 15.7 8.4 7.4 11.2 2.8 11.7 1.4 20.4 6.3 1.4 14.0 9.6 13.6 11.4 1.6 3.4 2.4 6.8 16.0 0.6 21.2 26.2 17.4 10.8 0.9 4.0 0.1 2.8 10.2 10.7 10.4 1.5 7.5 22.0 10.0 3.6 5.2 3.9 5.2 5.7 0.0 4.6 13.3 4.3 19.7 24.0 9.7 17.1 0.1 0.0 1.7 50.2 3.3 0.0 0.0 2.2 1.2 5.7 0.2 16.6 0.1 10.6 3.2 0.1 5.5 3.2 8.0 2.6 3.0 18.5 4.7 36.0 8.7 9.3 22.0 11.0 2.9 0.0 0.1 7.0 0.1 40.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 10.0 13.2 8.7 10.9 12.6 8.1 11.1 11.9 9.6 8.4 11.7 13.6 30.5 28.9 15.1 212.5 0.1 2.4 2.8 1.1 4.0 5.3 8.6 5.1 19.8 7.2 2.0 9.2 0.0 9.4 4.2 11.8 0.0 7.7 1.2 5.5 26.6 18.4 6.7 0.0 120.7 2.2 3.7 18.8 10.7 6.4 5.1 6.2 17.9 10.7 16.7 5.0 135.6 4.4 0.0 8.8 6.8 1.4 7.2 10.8 14.2 167.7 0.8 1.1 0.0 212.6 470.9 5.5 4.3 7.5 4.7 4.4 3.4 2.1 6.3 0.4 13.1 15.6 33.1 0.1 0.3 1.0 2.3 7.5 0.6 31.1 5.4 1.5 STARD3NL "MENTHO, MGC3251" ENSG00000010270 "STARD3 N-terminal like" O95772 7 38178245-38230670 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019204 Enhanced Supported Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA019204: AB_2197800" "unprognostic (1.55e-3)" "unprognostic (2.80e-3)" "unprognostic (2.22e-1)" "unprognostic (2.58e-1)" "unprognostic (4.37e-2)" "prognostic unfavorable (2.20e-4)" "prognostic unfavorable (1.44e-5)" "unprognostic (9.64e-2)" "unprognostic (1.89e-1)" "unprognostic (5.37e-2)" "prognostic favorable (8.48e-4)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.41e-2)" "unprognostic (8.09e-3)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" 26.8 21.8 35.5 23.1 37.6 37.8 22.0 39.6 41.7 31.4 29.8 21.5 18.5 32.6 27.1 12.3 27.5 22.0 27.1 35.7 44.1 34.0 17.4 32.8 21.3 42.0 46.8 24.2 16.4 17.9 25.5 49.4 48.4 40.6 23.5 26.3 14.9 21.6 17.3 6.6 20.3 33.1 40.5 27.1 17.6 32.7 41.8 22.3 32.7 17.5 15.3 29.4 14.8 42.9 40.9 42.7 92.6 60.4 62.8 62.2 32.4 65.2 67.2 63.2 82.4 34.3 63.0 31.9 64.0 59.9 192.0 42.9 51.4 49.5 95.2 29.0 45.1 64.8 22.1 47.4 55.3 71.5 72.7 58.8 24.0 67.0 53.0 72.0 116.7 86.1 75.0 53.7 98.4 25.1 40.9 115.2 65.5 33.7 33.9 49.6 85.9 14.9 89.0 37.5 36.9 86.7 22.4 58.8 64.1 127.0 40.9 93.8 80.0 43.0 61.0 67.8 93.5 57.4 62.2 12.1 87.0 125.6 142.4 33.5 46.8 56.2 52.2 43.3 23.9 30.8 21.6 39.3 42.3 28.4 18.1 35.6 53.1 71.8 47.0 30.3 24.8 47.1 35.5 37.6 39.6 41.7 35.7 44.1 42.0 46.8 48.4 40.5 41.8 42.9 45.8 19.2 47.3 15.0 33.2 20.8 57.3 43.4 20.5 8.7 26.8 15.0 18.2 14.3 25.9 31.3 12.5 48.3 67.2 15.5 31.3 31.4 125.3 37.0 42.5 45.5 21.5 28.2 21.9 34.3 91.2 34.2 19.9 33.1 23.5 36.0 51.0 12.4 65.8 5.0 24.5 20.9 32.6 63.2 77.9 115.2 18.3 56.8 26.6 17.8 24.2 34.6 114.4 27.6 26.0 34.0 21.6 25.9 34.3 55.2 19.4 50.1 22.8 13.0 13.1 23.4 38.4 48.8 37.3 12.2 16.2 42.3 47.5 24.5 19.5 46.4 STARD4 ENSG00000164211 "StAR related lipid transfer domain containing 4" Q96DR4 5 111496033-111512590 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046177, HPA048081" Approved Approved "Plasma membrane" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "HPA046177: AB_2679570, HPA048081: AB_2680253" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (1.01e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (4.80e-5)" "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (4.26e-1)" "unprognostic (6.27e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (2.00e-1)" "unprognostic (3.82e-3)" "unprognostic (4.01e-3)" "prognostic unfavorable (2.84e-4)" 6.2 15.8 8.3 15.9 15.8 19.4 3.9 25.2 12.6 10.2 11.5 14.7 40.8 7.7 16.2 8.5 5.0 9.7 15.0 9.5 10.6 8.5 34.1 20.9 12.6 16.0 16.7 6.5 6.1 14.4 8.2 27.3 13.8 20.7 16.9 12.0 6.6 9.9 1.5 2.5 35.7 6.9 10.1 12.1 17.9 6.8 14.8 7.2 9.0 1.7 10.1 7.7 9.2 11.3 20.6 10.0 48.2 29.4 42.4 84.0 16.3 21.0 46.6 29.8 89.1 37.7 59.9 24.5 8.4 13.4 89.0 9.1 24.8 71.8 28.8 23.7 10.4 19.1 33.3 22.8 46.4 9.5 11.7 44.6 48.3 64.1 47.6 35.6 56.6 23.5 10.7 46.5 20.8 3.9 23.7 17.3 16.6 0.6 5.5 5.4 53.3 22.5 44.6 6.7 27.2 105.6 0.0 12.3 19.0 32.1 16.0 30.4 84.4 25.6 22.9 17.2 8.9 15.9 15.8 21.6 24.3 34.8 13.2 7.1 1.4 0.9 2.5 2.1 1.3 1.7 1.2 1.9 1.8 1.7 1.2 1.9 0.0 2.1 1.5 1.3 0.8 1.4 8.3 15.8 25.2 12.6 9.5 10.6 16.0 16.7 13.8 10.1 14.8 11.3 8.2 25.6 34.8 16.0 13.1 1.0 1.4 35.0 1.2 10.8 1.6 0.4 17.8 8.6 18.1 9.2 8.4 15.6 24.8 37.3 1.9 7.8 9.4 6.7 3.5 20.2 21.4 3.6 38.8 9.2 6.0 6.0 15.8 11.5 32.3 6.5 5.0 39.9 20.3 6.7 20.8 32.5 22.4 19.6 26.7 8.3 7.2 27.8 3.6 20.6 5.7 7.1 9.2 20.1 23.6 10.0 30.0 7.9 17.6 3.3 30.1 5.7 9.5 7.6 19.7 2.4 15.2 8.7 9.4 6.8 2.6 14.1 14.5 38.2 23.0 5.2 STC2 STC-2 ENSG00000113739 "Stanniocalcin 2" O76061 5 173314723-173328447 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 143.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 278.3;Breast myoepithelial cells: 119.6;Extravillous trophoblasts: 59.5" "Cancer enriched" "Detected in all" 6 "breast cancer: 91.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 1019.9;T-47d: 940.0;U-138 MG: 382.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA045372 Approved Approved "Endoplasmic reticulum" "Secreted in other tissues" NA NA 19000000 "Cluster 5: Breast - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "Endoplasmic reticulum" "HPA045372: AB_10961040" "prognostic favorable (7.40e-5)" "unprognostic (2.40e-2)" "unprognostic (9.03e-3)" "unprognostic (1.21e-1)" "unprognostic (1.89e-3)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (3.07e-5)" "unprognostic (5.28e-3)" "unprognostic (6.12e-3)" "unprognostic (1.53e-1)" "unprognostic (2.13e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.17e-8)" "prognostic unfavorable (7.57e-4)" "unprognostic (8.56e-2)" "unprognostic (5.06e-2)" "unprognostic (7.93e-3)" 7.4 1.7 0.7 2.4 0.9 0.0 143.6 2.2 3.1 13.2 1.9 4.8 0.6 3.0 0.3 2.0 2.0 6.4 9.9 3.0 1.8 3.6 0.8 11.3 1.1 5.0 6.4 0.7 32.6 3.3 1.7 28.0 3.7 4.8 0.6 7.7 1.0 6.7 4.4 12.8 2.7 21.2 1.3 11.5 3.4 0.7 2.9 0.2 9.1 4.9 0.3 4.7 3.0 3.0 52.5 15.3 2.7 13.0 47.9 20.5 133.8 234.5 239.4 59.1 115.0 74.4 36.7 0.0 33.4 139.8 298.2 21.5 33.8 72.0 102.5 0.1 18.9 0.0 26.7 50.2 311.3 15.8 4.3 43.6 117.9 133.3 7.9 274.4 16.7 42.4 2.4 0.1 1019.9 41.6 0.7 0.7 7.9 23.4 73.2 0.3 36.5 27.4 0.0 3.9 35.6 9.6 10.3 1.1 42.5 10.4 940.0 15.9 151.5 382.8 1.3 229.1 49.2 42.0 24.3 10.5 74.6 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 2.2 3.1 3.0 1.8 5.0 6.4 3.7 1.3 2.9 3.0 6.9 0.0 0.0 0.0 0.4 5.0 0.2 4.9 0.6 11.1 278.3 119.6 27.1 0.0 0.6 0.0 0.0 37.0 2.4 0.4 0.0 31.6 0.6 9.5 1.0 25.3 7.2 0.0 0.2 13.1 59.5 16.7 0.0 16.1 0.0 0.0 3.6 0.0 5.2 0.0 0.2 0.2 0.0 0.0 4.8 1.0 23.0 0.5 10.6 1.0 0.0 0.9 0.0 0.0 0.1 7.8 0.0 0.4 0.0 0.8 0.0 4.5 0.2 2.4 0.0 2.3 24.6 0.7 0.8 0.5 6.3 21.9 1.0 0.9 0.4 0.5 STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 402.5;Club cells: 152.8;Sertoli cells: 460.2;Smooth muscle cells: 255.3" "Cancer enhanced" "Detected in many" "prostate cancer: 45.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 12 "neutrophil: 163.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 163.6" "Group enriched" "Detected in some" 6 "HSkMC: 122.1;SiHa: 119.7;U-2197: 166.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "prognostic favorable (2.97e-4)" "unprognostic (7.40e-2)" "unprognostic (3.12e-1)" "unprognostic (4.66e-2)" "unprognostic (4.21e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (4.53e-2)" 113.7 46.3 1.0 31.7 0.9 7.1 68.6 2.8 1.5 21.3 17.0 13.3 3.8 17.9 7.8 15.4 36.1 22.7 24.1 1.4 1.0 11.8 24.3 67.5 7.2 1.2 0.9 4.4 10.6 16.0 13.0 15.3 0.8 60.0 9.2 1.9 26.8 10.6 13.4 19.3 10.6 29.3 0.4 5.4 10.6 13.4 1.1 7.8 53.1 16.6 5.1 34.3 22.7 1.1 4.9 0.0 0.1 0.1 0.1 1.9 0.3 0.0 0.3 0.0 0.1 0.1 23.6 0.1 0.1 0.0 0.4 18.7 0.1 0.0 0.1 0.0 0.1 0.1 7.9 0.1 0.1 0.1 0.2 122.1 0.1 0.4 0.9 0.0 0.0 0.1 0.3 0.4 0.0 3.0 0.1 0.5 0.1 1.0 0.0 0.2 0.1 0.3 0.0 0.3 0.2 0.2 119.7 9.9 0.0 0.1 0.8 0.0 0.1 0.4 0.3 166.4 0.1 0.1 0.1 0.1 0.2 0.9 0.2 0.4 13.5 1.4 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 163.6 0.2 0.1 0.3 0.0 3.2 1.0 0.9 2.8 1.5 1.4 1.0 1.2 0.9 0.8 0.4 1.1 1.1 77.2 54.5 402.5 0.0 0.8 9.4 5.8 8.6 1.8 1.8 21.6 8.3 9.1 0.0 152.8 0.0 2.1 0.4 1.1 0.4 0.0 14.6 23.8 14.6 20.5 14.7 0.0 0.0 0.5 9.6 10.6 39.8 1.1 51.2 16.4 0.0 15.4 0.7 2.8 0.0 0.8 0.2 16.2 7.2 7.4 10.9 114.9 12.2 5.4 6.5 19.0 2.7 0.0 1.0 0.1 18.6 0.0 9.1 0.2 49.3 0.1 0.1 72.8 0.3 460.2 9.6 255.3 0.9 0.3 1.5 18.8 10.9 3.1 57.7 0.2 16.6 STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Glandular and luminal cells: 12.4;Spermatocytes: 17.8;Spermatogonia: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046543 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA046543: AB_2679692" "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" 1.0 0.5 0.8 3.0 0.8 10.8 2.9 0.7 1.2 1.1 0.2 4.1 2.9 1.4 1.4 2.5 0.9 1.4 0.6 0.8 0.6 0.7 1.0 0.9 4.9 0.7 0.6 0.8 0.7 0.9 0.4 1.9 0.8 1.3 5.6 1.2 1.7 0.5 0.6 3.1 2.7 1.4 0.4 1.4 1.8 6.6 0.8 9.9 0.9 0.7 5.7 1.1 1.0 1.0 33.7 17.4 24.7 22.1 1.8 3.8 15.7 29.3 14.0 32.0 33.2 18.5 16.1 39.4 13.3 14.4 32.7 21.4 29.4 15.3 33.7 29.6 12.9 44.5 20.9 16.6 0.8 35.7 21.5 1.6 2.1 27.2 17.5 3.8 21.5 29.5 31.7 35.9 24.1 14.3 35.6 10.9 30.0 18.6 14.2 23.0 40.3 19.0 9.0 20.0 22.0 13.2 31.4 22.2 14.6 29.6 14.5 20.6 12.2 29.6 29.9 21.2 40.0 11.9 26.4 38.1 13.8 27.0 28.0 0.3 0.1 0.2 0.2 0.0 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.7 0.0 0.3 0.3 0.1 0.8 0.8 0.7 1.2 0.8 0.6 0.7 0.6 0.8 0.4 0.8 1.0 1.6 3.2 0.5 2.0 2.4 0.9 0.6 2.0 1.2 1.1 2.8 3.0 0.5 0.0 2.3 0.0 4.2 2.5 1.6 5.4 0.0 1.6 1.6 7.8 3.2 2.2 1.8 12.8 5.1 0.4 4.4 1.6 3.1 12.4 2.5 8.2 1.4 0.5 2.9 0.0 3.9 6.1 0.0 2.4 1.2 1.1 0.3 2.7 0.0 0.0 3.0 0.8 1.0 2.0 4.8 1.9 1.8 0.7 10.2 1.1 1.4 0.4 7.6 0.6 0.0 1.7 2.0 17.8 14.4 5.3 2.4 0.8 3.3 2.6 5.5 1.4 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042079-172188224 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 76.5;lymphoid tissue: 45.2" "Cell type enhanced" "Detected in all" "dendritic cells: 107.7;Kupffer cells: 91.4;NK-cells: 171.0;T-cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 143.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 16000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: AB_2669151" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favorable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 14.9 5.7 3.1 37.1 3.6 76.5 11.4 18.4 5.6 4.5 3.5 8.5 8.4 4.9 1.7 5.6 4.7 13.2 7.6 3.1 4.0 5.9 6.2 18.4 44.1 6.2 4.4 2.5 7.2 3.1 4.1 17.2 5.8 4.4 6.9 1.2 4.7 3.5 5.0 14.2 16.0 7.8 5.4 45.2 11.1 14.0 6.4 20.6 5.3 5.5 25.0 14.9 5.2 7.0 22.2 20.2 12.7 18.8 14.7 18.1 31.5 28.4 24.0 20.2 18.9 10.6 28.6 26.8 14.6 35.6 42.3 25.4 5.7 35.1 13.5 35.0 9.3 32.1 8.2 6.1 20.2 32.7 36.4 17.4 7.5 27.4 23.1 7.5 18.3 10.4 3.0 36.2 14.7 35.7 23.5 73.4 5.0 11.3 16.1 38.2 9.9 17.7 8.2 27.6 8.3 10.2 16.4 22.5 77.9 15.6 8.2 68.7 24.8 22.3 11.3 15.8 15.5 30.2 48.4 17.1 29.4 49.8 143.3 16.7 26.5 23.4 36.5 46.3 26.9 10.0 19.3 26.3 22.5 8.1 11.0 20.0 48.9 16.9 71.8 7.1 26.7 44.0 3.1 3.6 18.4 5.6 3.1 4.0 6.2 4.4 5.8 5.4 6.4 7.0 35.8 3.2 11.2 1.6 40.5 6.6 8.4 7.2 5.7 4.3 3.3 3.7 3.8 5.7 6.1 1.8 6.2 4.1 107.7 11.8 1.9 4.5 2.5 3.5 4.6 23.9 12.0 11.8 8.5 6.2 27.2 9.3 20.9 7.1 28.4 3.6 18.2 2.3 36.3 47.1 7.9 19.9 2.0 91.4 43.8 3.2 2.8 61.3 8.8 32.8 49.8 2.1 171.0 10.1 14.4 10.7 11.8 1.5 42.8 11.7 6.5 2.0 6.1 2.2 13.1 5.1 10.2 5.3 7.8 2.6 4.1 5.1 81.4 11.4 5.3 10.7 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387855 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.2;brain: 24.4" "Cell type enriched" "Detected in many" 19 "Oligodendrocyte precursor cells: 306.6" "Group enriched" "Detected in many" 5 "glioma: 4.3;melanoma: 11.9;thyroid cancer: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 13.6;SK-MEL-30: 48.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 1.3 11.2 5.9 0.6 9.5 0.0 1.2 13.2 3.1 1.0 1.0 2.3 0.5 0.5 2.6 0.3 0.8 1.5 1.0 3.5 14.4 3.4 0.1 1.2 0.0 11.7 24.4 2.5 2.6 0.1 8.1 0.1 17.0 1.0 0.3 2.6 0.9 0.8 0.2 3.7 0.7 0.4 10.4 0.3 1.2 1.0 14.0 0.1 8.7 0.5 0.0 1.7 1.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.2 4.4 13.6 1.2 0.5 0.0 0.0 48.6 0.2 0.0 0.0 0.1 0.0 0.5 0.7 0.4 1.0 0.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 9.5 13.2 3.1 3.5 14.4 11.7 24.4 17.0 10.4 14.0 10.1 0.2 0.0 2.6 8.5 0.0 1.5 0.2 1.4 0.0 1.8 1.3 0.5 0.5 0.0 1.0 1.8 0.0 0.0 0.0 0.1 1.9 1.8 6.9 0.2 0.5 0.1 0.0 0.0 4.6 2.7 0.0 2.7 0.0 0.7 0.0 4.2 0.0 0.0 0.1 0.0 5.2 0.0 2.0 0.0 1.0 10.5 0.9 0.2 16.0 0.0 0.0 4.0 0.0 306.6 0.7 5.5 0.0 4.1 0.0 0.3 0.0 4.1 0.2 1.0 0.0 5.4 0.5 0.0 0.1 0.0 0.3 0.1 0.1 1.4 0.0 0.6 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168247595 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 159.9;Inhibitory neurons: 142.9;Oligodendrocyte precursor cells: 153.3;Oligodendrocytes: 359.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 80000 "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: AB_2684616, HPA062802: AB_2684870" "prognostic favorable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 19.4 6.7 20.1 14.0 25.8 5.1 8.4 25.3 25.1 12.0 52.9 26.3 32.0 7.3 14.5 36.3 6.4 18.1 15.8 16.0 18.6 9.0 1.9 7.6 22.2 28.8 25.8 6.6 25.6 13.7 8.2 2.3 31.9 28.7 32.4 27.8 67.9 11.5 2.7 6.3 18.6 11.7 20.8 8.6 31.8 48.5 25.6 29.1 6.9 7.6 23.5 24.8 9.5 37.0 19.1 10.9 40.9 12.9 28.1 37.5 4.0 45.0 33.8 29.6 27.8 0.2 59.9 51.1 12.2 30.5 25.5 46.6 26.7 34.4 37.1 16.2 16.4 21.2 11.8 42.9 52.3 30.5 2.1 29.1 52.8 35.1 36.5 38.5 21.2 41.3 0.5 0.0 67.0 11.4 51.6 13.0 30.3 41.0 24.3 72.1 16.0 4.8 27.9 47.6 65.7 27.0 15.7 2.6 21.8 20.3 8.0 25.9 20.2 36.6 11.1 26.5 32.2 0.1 0.0 41.5 29.7 28.5 25.1 0.0 0.3 0.0 1.1 0.2 0.6 0.2 0.9 1.6 0.5 0.5 0.2 0.8 0.0 1.0 0.1 0.1 1.8 0.2 20.1 25.8 25.3 25.1 16.0 18.6 28.8 25.8 31.9 20.8 25.6 37.0 6.1 3.2 14.0 64.6 6.4 3.8 34.4 6.5 5.7 14.8 5.5 6.5 26.2 18.6 15.2 5.5 16.7 0.1 30.0 47.7 21.5 10.9 29.4 11.9 11.6 5.6 22.8 5.7 159.9 23.1 0.1 9.2 28.1 18.9 0.0 5.8 2.9 0.4 3.5 20.2 142.9 17.3 14.2 6.7 6.7 16.2 10.2 6.7 17.8 64.6 5.5 28.9 12.3 153.3 359.4 36.0 20.1 11.3 9.5 74.8 14.5 7.9 17.5 30.0 6.6 7.7 18.2 25.4 8.1 7.5 4.4 0.3 19.4 15.8 22.4 50.6 STK40 "MGC4796, SgK495" ENSG00000196182 "Serine/threonine kinase 40" Q8N2I9 1 36339624-36385924 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.7;Late spermatids: 236.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 25.2" "Group enriched" "Detected in all" 5 "granulocytes: 25.2;monocytes: 12.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008026 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 17: WM-115 - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA008026: AB_1857603" "unprognostic (3.32e-1)" "unprognostic (3.00e-1)" "unprognostic (6.47e-2)" "unprognostic (4.55e-1)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (2.69e-3)" "unprognostic (6.09e-2)" "unprognostic (2.09e-1)" "unprognostic (5.96e-2)" "prognostic favorable (5.59e-4)" "unprognostic (1.19e-1)" "unprognostic (2.75e-2)" "unprognostic (7.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" 33.3 15.5 17.4 23.1 17.0 15.2 24.6 16.6 19.9 24.3 14.1 44.8 13.5 23.6 8.1 43.8 24.7 20.4 42.7 17.5 17.6 33.5 45.3 36.4 24.3 24.8 19.0 40.3 45.7 21.8 30.1 13.5 20.6 28.5 12.7 7.5 32.0 23.1 125.2 38.8 23.7 20.0 19.9 35.4 35.5 52.5 20.1 15.6 25.3 39.6 21.4 41.7 26.7 19.8 17.4 7.4 36.6 38.3 25.3 14.7 20.5 17.2 23.1 20.3 21.8 41.3 24.2 73.0 13.8 16.1 21.5 17.1 33.5 7.4 14.9 32.0 26.4 47.7 7.5 53.3 25.1 28.1 60.9 13.3 27.7 15.6 8.2 10.9 12.9 55.2 59.7 25.7 12.9 27.0 29.3 37.1 23.5 31.2 10.2 33.3 24.9 49.1 12.7 19.2 44.6 22.7 13.2 20.5 58.5 23.1 13.9 32.7 21.6 12.7 26.5 37.7 38.3 26.6 16.2 61.3 66.3 24.3 42.8 1.2 3.8 6.8 3.1 8.6 3.6 2.8 2.1 2.2 3.5 2.9 1.2 1.8 25.2 2.1 12.0 3.3 1.3 3.5 17.4 17.0 16.6 19.9 17.5 17.6 24.8 19.0 20.6 19.9 20.1 19.8 10.7 12.8 15.3 11.8 22.0 61.3 54.0 9.4 16.5 11.8 28.3 15.4 25.3 8.6 11.1 11.0 4.2 6.5 15.8 34.8 17.6 21.2 116.7 23.9 11.2 15.2 23.4 7.8 24.8 31.6 10.7 19.2 33.1 36.5 13.3 4.9 14.3 23.7 24.7 10.1 17.3 15.5 12.2 23.3 69.5 236.8 23.0 32.2 30.2 21.5 19.2 4.9 18.6 7.5 12.3 28.5 16.3 33.4 17.0 57.1 6.2 14.9 25.6 10.5 26.3 20.6 18.6 14.9 11.1 28.7 75.4 57.2 17.3 17.6 15.1 51.3 STMN3 SCLIP ENSG00000197457 "Stathmin 3" Q9NZ72 20 63639705-63657682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 291.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.5;Granulosa cells: 254.2;Horizontal cells: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in many" 5 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "AN3-CA: 125.1;MOLT-4: 142.0;REH: 143.8;SCLC-21H: 192.5;SH-SY5Y: 146.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012947 Enhanced Supported "Golgi apparatus,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 14: REH - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" Cytosol "HPA012947: AB_1857606" "unprognostic (7.59e-2)" "unprognostic (4.36e-1)" "unprognostic (5.28e-2)" "unprognostic (2.33e-1)" "unprognostic (3.60e-2)" "unprognostic (6.30e-2)" "unprognostic (2.75e-1)" "unprognostic (1.10e-1)" "unprognostic (2.92e-2)" "unprognostic (4.35e-2)" "unprognostic (1.65e-3)" "unprognostic (7.52e-2)" "unprognostic (2.52e-3)" "unprognostic (2.73e-2)" "unprognostic (9.87e-2)" "unprognostic (4.08e-2)" "unprognostic (9.08e-3)" 23.4 49.7 188.4 21.3 197.6 11.4 20.0 112.5 291.7 29.2 16.6 26.5 5.5 30.0 5.0 11.6 27.9 10.9 17.1 215.0 162.0 24.8 3.7 23.6 25.8 259.6 158.1 50.5 16.4 17.5 102.2 10.0 266.1 24.3 5.2 38.8 11.7 12.7 4.3 20.2 24.8 14.7 100.8 48.2 15.1 9.0 159.3 43.5 63.9 3.7 12.4 21.9 19.0 179.9 10.4 11.6 74.4 125.1 1.9 7.3 5.1 12.0 0.4 35.8 16.8 73.6 13.7 0.5 36.3 4.6 2.0 68.6 52.2 1.3 11.1 5.2 14.0 5.1 17.0 27.6 9.9 3.9 42.0 15.3 0.3 11.5 2.9 1.5 1.3 34.4 98.8 2.2 9.6 11.7 142.0 17.7 76.5 2.4 81.7 143.8 12.1 58.0 60.9 2.0 192.5 146.6 5.7 3.4 14.9 5.9 2.1 25.9 1.9 0.8 20.4 0.8 2.6 4.9 10.4 3.6 2.1 14.3 48.8 1.1 0.0 1.1 2.5 0.1 2.7 0.2 5.2 4.5 0.1 0.6 6.2 5.3 0.1 0.0 0.1 1.1 0.9 2.0 188.4 197.6 112.5 291.7 215.0 162.0 259.6 158.1 266.1 100.8 159.3 179.9 5.8 6.4 2.5 16.3 17.1 8.2 6.9 11.9 8.6 108.5 4.7 14.7 2.3 4.3 3.2 3.7 52.1 11.7 13.4 1.1 13.7 4.0 10.0 1.6 17.9 7.8 37.2 4.6 56.9 2.5 4.0 25.4 2.0 2.7 4.5 254.2 6.8 0.0 2.3 109.4 67.1 0.6 4.1 2.2 7.6 18.8 30.1 3.5 7.2 7.5 4.6 37.2 16.5 21.1 11.3 2.2 0.1 35.7 5.3 4.5 0.1 5.0 0.8 44.5 13.1 3.0 20.9 3.3 6.7 1.6 4.3 8.8 28.6 51.0 0.6 2.7 STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.0;Muller glia cells: 33.4;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 23.7;ASC TERT1: 28.6;HSkMC: 36.1;hTERT-RPE1: 17.0;SuSa: 19.6" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA005715: AB_1080113" "unprognostic (1.61e-1)" "unprognostic (4.44e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-4)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (8.99e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.06e-2)" "unprognostic (2.50e-1)" "unprognostic (8.68e-2)" "unprognostic (2.49e-3)" 20.8 5.2 2.3 5.7 2.8 0.5 10.9 10.5 2.0 10.5 10.7 34.5 3.6 27.4 4.6 16.0 17.2 15.6 6.4 1.9 7.1 9.3 2.1 10.9 2.8 33.2 12.5 24.5 1.9 2.1 2.8 18.4 25.9 21.7 8.4 18.1 2.5 19.3 2.2 4.1 7.9 25.1 25.6 7.4 13.0 1.1 4.1 2.5 4.6 6.3 1.4 22.2 10.5 29.2 0.1 0.0 8.6 0.1 23.7 28.6 4.9 1.0 9.2 0.9 2.1 0.1 0.0 0.0 0.3 12.0 4.6 9.0 8.3 0.3 1.7 0.1 2.3 1.4 0.6 0.0 13.5 0.0 0.4 36.1 1.7 2.5 1.0 17.0 16.4 0.8 0.2 0.2 5.7 0.5 0.7 0.3 8.0 0.0 0.1 1.3 1.7 0.0 0.9 6.6 0.3 1.9 0.7 1.5 4.0 19.6 0.7 0.3 8.8 3.0 2.3 0.0 0.7 0.5 0.1 0.0 1.6 0.1 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.3 2.8 10.5 2.0 1.9 7.1 33.2 12.5 25.9 25.6 4.1 29.2 16.4 0.0 0.5 0.0 1.1 2.4 15.4 1.1 16.5 3.8 0.8 1.8 2.3 0.0 0.8 5.5 2.1 15.1 0.5 0.6 3.9 0.8 0.4 1.9 42.0 7.7 2.4 0.0 0.0 0.4 1.0 9.9 0.5 2.6 0.0 3.9 11.4 0.2 2.7 13.5 0.0 0.3 0.0 1.3 2.8 0.9 12.2 1.6 0.0 0.0 1.2 33.4 1.0 0.0 0.0 0.4 0.3 10.1 0.2 13.8 0.4 2.0 0.6 2.3 26.3 1.9 15.1 0.3 1.7 1.9 2.4 12.6 1.5 2.6 0.9 14.3 STRA6 FLJ12541 ENSG00000137868 "Signaling receptor and transporter of retinol STRA6" Q9BX79 15 74179466-74212267 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Receptor "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.5" "Cell type enhanced" "Detected in many" "Club cells: 17.6;Endometrial stromal cells: 43.1;Extravillous trophoblasts: 12.1;Fibroblasts: 16.1;Proximal tubular cells: 10.3;Syncytiotrophoblasts: 26.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 33.7;CAPAN-2: 94.5;SH-SY5Y: 59.2;WM-115: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040839 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA040839: AB_10794881" "unprognostic (1.20e-2)" "unprognostic (4.99e-2)" "unprognostic (3.71e-2)" "unprognostic (3.55e-3)" "unprognostic (1.37e-1)" "unprognostic (2.09e-2)" "unprognostic (4.38e-3)" "unprognostic (1.67e-2)" "unprognostic (9.16e-2)" "unprognostic (1.21e-1)" "unprognostic (5.35e-2)" "unprognostic (3.89e-1)" "unprognostic (7.91e-13)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-2)" "unprognostic (1.91e-1)" 0.1 1.0 0.1 0.3 0.0 0.0 0.9 0.0 0.4 24.5 0.4 0.1 0.0 4.3 0.5 1.1 3.6 0.3 0.1 0.1 0.1 4.3 0.0 0.2 0.8 0.1 0.0 0.6 0.1 0.0 5.5 7.6 0.0 5.2 0.0 0.0 0.7 1.4 0.0 0.3 0.2 0.2 0.1 0.1 0.0 3.1 0.3 0.2 0.1 0.1 0.5 1.3 2.4 0.0 0.5 33.7 1.9 0.1 0.0 0.0 6.0 1.0 0.2 0.0 0.0 11.7 94.5 0.0 22.1 0.1 0.7 3.4 1.8 0.0 0.0 0.0 0.2 3.0 1.3 2.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.4 6.1 0.6 2.9 0.1 0.0 0.4 0.0 0.0 0.0 2.9 17.4 59.2 0.0 3.6 0.0 3.6 0.2 0.1 0.0 0.2 7.3 0.6 1.6 0.1 0.2 0.0 0.6 0.0 142.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.4 1.0 9.7 0.0 0.0 0.2 0.3 1.0 0.0 17.6 0.0 0.0 4.2 0.0 0.0 1.9 0.3 1.7 2.1 43.1 1.3 0.0 0.0 0.1 0.0 12.1 16.1 0.0 1.8 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 2.0 0.0 0.8 0.8 6.8 0.4 1.8 1.9 0.1 0.0 0.0 0.0 0.0 4.7 0.0 4.1 0.0 0.4 0.0 10.3 6.6 0.0 0.0 1.3 4.7 0.5 0.5 0.0 0.0 26.4 0.3 0.1 0.0 1.3 STRA8 ENSG00000146857 "Stimulated by retinoic acid 8" Q7Z7C7 7 135231979-135258492 "Predicted intracellular proteins" "Differentiation, DNA replication, Meiosis, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "choroid plexus: 6.6" "Cell type enriched" "Detected in some" 6 "Spermatogonia: 10.8" "Cancer enhanced" "Detected in many" "renal cancer: 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.5;THP-1: 2.4;U-266/84: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA078044 Approved Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Cytosol "HPA078044: " "unprognostic (2.84e-1)" "unprognostic (4.86e-2)" "unprognostic (3.89e-2)" "unprognostic (9.67e-4)" "unprognostic (1.21e-1)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (1.26e-3)" "unprognostic (1.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.45e-1)" "unprognostic (2.69e-1)" 0.1 0.0 0.6 0.0 0.5 0.0 0.0 0.3 0.5 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.3 0.0 0.1 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 2.4 0.1 0.1 0.0 0.0 0.0 0.2 1.5 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.3 0.5 1.0 0.3 0.6 0.5 0.6 0.3 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 10.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 STX2 "EPIM, EPM, STX2A, STX2B, STX2C" ENSG00000111450 "Syntaxin 2" P32856 12 130789600-130839266 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 152.2;Endometrial ciliated cells: 86.4;Late spermatids: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079007" Uncertain Supported Approved "Nuclear membrane,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "Nuclear membrane" "CAB079007: , HPA069176: AB_2686098" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (8.29e-2)" "unprognostic (2.22e-1)" "unprognostic (3.38e-2)" "unprognostic (9.85e-2)" "unprognostic (2.11e-2)" "unprognostic (4.16e-2)" "unprognostic (2.83e-1)" "unprognostic (7.62e-2)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.15e-5)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.63e-2)" "unprognostic (3.41e-3)" 17.7 11.0 11.2 9.1 11.7 6.4 12.0 12.3 13.4 15.1 24.7 21.2 4.2 14.3 9.8 6.0 16.3 9.9 17.0 12.2 12.1 14.4 13.3 17.8 8.6 15.5 12.3 15.3 10.9 5.9 14.6 13.2 14.5 8.4 6.8 16.7 5.0 10.6 6.7 5.1 11.4 17.2 13.0 12.4 11.4 17.0 11.8 6.9 12.4 7.9 6.2 14.5 10.7 16.3 9.6 18.3 26.8 22.4 27.8 63.2 2.8 44.2 35.8 50.8 35.7 5.5 6.6 11.7 6.6 50.5 16.4 2.8 24.4 6.6 54.9 18.7 9.2 6.4 15.9 15.7 30.6 9.2 15.5 23.4 8.3 24.9 20.1 48.2 27.6 12.7 25.7 11.2 46.2 5.6 13.3 10.6 17.9 2.9 28.2 13.7 18.9 7.0 28.7 2.1 24.3 25.4 20.4 1.8 18.1 23.4 6.1 6.4 36.5 30.1 20.3 33.1 19.6 8.1 6.7 7.9 35.0 10.8 24.4 1.0 0.4 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.3 0.3 0.6 0.6 0.4 0.2 0.2 0.3 0.4 0.2 11.2 11.7 12.3 13.4 12.2 12.1 15.5 12.3 14.5 13.0 11.8 16.3 35.3 22.4 14.8 20.5 6.2 3.4 1.2 2.1 3.4 5.6 2.1 3.0 17.2 11.5 6.9 29.5 0.0 1.8 12.3 0.4 9.8 19.1 152.2 86.4 40.0 22.4 6.7 32.4 33.6 7.4 7.1 26.5 2.6 7.6 1.3 10.9 17.9 19.0 11.5 0.0 17.6 0.7 2.0 11.5 12.3 114.4 28.0 15.1 14.2 23.4 10.3 12.3 6.2 15.1 24.3 14.5 0.1 24.5 10.2 2.0 0.1 17.6 33.9 31.4 13.1 26.1 29.6 42.0 34.2 1.7 1.4 0.8 14.2 11.7 0.6 0.5 STXBP1 "hUNC18, MUNC18-1, rbSec1, UNC18" ENSG00000136854 "Syntaxin binding protein 1" P61764 9 127579370-127696027 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 174.5;pituitary gland: 66.4;retina: 214.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 131.0;Cone photoreceptor cells: 156.4;Excitatory neurons: 243.2;Inhibitory neurons: 157.5;Rod photoreceptor cells: 155.6" "Cancer enhanced" "Detected in all" "melanoma: 39.6" "Region enhanced" "Detected in many" "cerebral cortex: 174.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 144.1;SK-MEL-30: 131.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008209, HPA023483, CAB034434" Enhanced Approved Nucleoplasm,Cytosol NA NA 29000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "CAB034434: AB_2196699, HPA008209: AB_1857624, HPA023483: AB_1857625" "unprognostic (2.32e-2)" "unprognostic (7.33e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.47e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.87e-2)" "unprognostic (2.31e-1)" "unprognostic (3.08e-3)" "prognostic favorable (9.81e-4)" "unprognostic (1.30e-2)" "unprognostic (1.67e-1)" "unprognostic (2.68e-2)" "unprognostic (5.51e-2)" "unprognostic (7.66e-2)" "unprognostic (3.36e-3)" 27.5 28.8 22.8 7.8 33.2 1.1 21.0 38.6 174.5 21.8 0.0 15.9 5.5 24.1 7.1 10.4 32.3 11.4 24.0 48.3 12.2 14.1 3.1 32.1 6.0 48.7 0.0 25.2 24.8 15.0 66.4 14.1 33.1 10.5 8.4 214.2 15.6 10.4 9.0 11.4 9.3 21.0 0.0 10.4 13.3 9.1 6.8 5.8 20.1 9.2 7.0 15.4 16.4 27.2 13.2 27.1 25.5 28.8 56.6 48.3 23.2 45.0 22.9 26.6 23.3 1.5 15.4 13.1 24.2 29.7 74.2 4.7 22.6 28.1 32.7 29.8 15.4 17.1 69.7 4.9 28.5 1.8 14.6 36.6 15.4 70.0 33.7 42.6 32.2 43.4 17.8 19.6 45.5 24.5 12.5 5.2 21.5 21.4 35.9 7.5 12.1 31.3 22.0 0.6 144.1 69.9 72.9 37.2 131.9 22.5 5.8 5.6 47.5 30.0 15.1 59.9 17.4 40.2 73.2 17.4 59.2 18.9 28.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.9 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.2 22.8 33.2 38.6 174.5 48.3 12.2 48.7 0.0 33.1 0.0 6.8 27.2 24.3 25.6 70.7 34.0 1.2 11.6 10.1 8.4 12.5 131.0 10.5 8.0 15.2 1.5 9.2 3.7 156.4 2.7 1.1 0.5 7.9 13.1 2.2 8.3 14.7 28.9 45.6 4.0 243.2 8.4 5.9 18.7 3.1 7.0 5.1 5.0 26.7 1.4 4.4 84.1 157.5 10.2 8.2 2.5 5.6 2.2 20.5 3.0 10.6 45.0 0.6 27.0 0.0 61.3 39.0 5.3 0.0 44.4 1.6 10.8 0.1 8.9 15.9 155.6 13.1 9.5 11.2 40.6 16.9 2.9 7.5 24.5 2.3 17.7 0.9 7.1 STXBP2 "Hunc18b, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636881-7647873 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 194.2" "Cell type enhanced" "Detected in many" "Kupffer cells: 262.5;Macrophages: 249.1;monocytes: 368.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 248.6;classical monocyte: 471.0;eosinophil: 295.6;intermediate monocyte: 604.8;myeloid DC: 239.7;neutrophil: 356.2;non-classical monocyte: 893.3" "Group enriched" "Detected in all" 6 "dendritic cells: 239.7;granulocytes: 356.2;monocytes: 893.3" "Cell line enhanced" "Detected in many" "HMC-1: 244.8;U-937: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 870000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA015564: AB_1857626, HPA063868: AB_2685136" "unprognostic (1.20e-2)" "unprognostic (6.17e-3)" "unprognostic (2.85e-2)" "prognostic favorable (2.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (4.65e-4)" "unprognostic (4.22e-3)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (1.51e-1)" "unprognostic (4.62e-2)" "unprognostic (2.85e-1)" "prognostic favorable (7.68e-4)" "prognostic favorable (5.13e-6)" 24.2 22.8 5.2 65.9 6.3 194.2 24.3 4.8 10.9 22.2 9.3 52.5 67.4 8.4 33.2 73.1 27.7 28.4 7.5 5.1 6.2 62.4 49.0 89.6 51.0 8.3 6.6 5.3 86.7 36.1 29.4 36.3 7.9 52.1 37.0 4.2 79.4 22.8 2.9 52.3 63.9 14.6 6.7 162.2 71.9 74.9 8.8 85.3 52.0 3.0 34.6 34.6 34.8 9.3 113.0 39.1 0.9 0.5 0.0 0.9 75.6 14.2 1.5 2.7 7.4 92.5 69.6 29.6 55.4 11.3 49.5 75.5 4.1 67.5 2.7 124.1 46.9 127.8 49.7 55.8 63.6 83.2 244.8 4.4 67.4 13.4 38.0 0.3 58.5 74.7 81.4 98.5 0.0 70.9 41.2 193.2 28.7 72.7 68.0 41.8 0.3 114.7 55.0 128.1 11.5 0.6 34.0 49.6 2.2 35.6 61.9 212.7 61.7 0.4 21.8 1.5 0.8 108.4 58.6 38.8 1.2 224.8 2.7 248.6 471.0 295.6 69.9 604.8 56.7 47.3 52.7 63.8 239.7 52.2 36.6 44.3 356.2 74.7 893.3 91.5 78.9 306.9 5.2 6.3 4.8 10.9 5.1 6.2 8.3 6.6 7.9 6.7 8.8 9.3 2.1 0.0 7.7 0.7 44.1 23.6 48.2 105.1 18.8 6.0 38.0 22.9 0.9 31.5 68.5 35.0 2.1 97.7 56.2 181.4 33.2 100.3 99.9 32.5 5.4 6.7 59.8 38.3 0.6 118.8 123.2 5.7 150.3 47.6 71.8 34.6 16.4 19.6 168.4 0.0 0.4 108.2 105.8 262.5 46.6 233.5 1.8 249.1 14.2 1.0 368.2 0.9 72.1 0.0 0.0 132.8 152.6 1.9 54.7 49.1 171.7 75.9 42.5 4.0 6.6 1.0 8.6 45.7 20.2 35.3 21.3 153.0 47.7 6.0 79.3 68.7 SULT1C4 "SULT1C, SULT1C2" ENSG00000198075 "Sulfotransferase family 1C member 4" O75897 2 108377911-108388989 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 13.3;Cholangiocytes: 37.1;Endothelial cells: 13.2;Granulosa cells: 15.3;Hepatic stellate cells: 17.9;Muller glia cells: 12.3;Oligodendrocyte precursor cells: 17.6" "Group enriched" "Detected in many" 6 "glioma: 7.1;renal cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.5;HUVEC TERT2: 10.7;SH-SY5Y: 42.0;SuSa: 11.6" "Low region specificity" "Detected in many" HPA034530 Approved Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA034530: AB_10670170" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-1)" "unprognostic (2.89e-1)" "unprognostic (5.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-2)" "unprognostic (5.77e-2)" "unprognostic (1.56e-3)" "unprognostic (1.68e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-3)" "prognostic favorable (9.99e-7)" "unprognostic (1.79e-2)" "unprognostic (2.96e-2)" "unprognostic (1.85e-2)" "unprognostic (1.38e-1)" 6.2 2.0 15.5 1.1 16.1 0.5 5.2 16.9 17.2 21.9 12.9 3.4 1.5 11.1 8.0 2.3 9.3 27.1 10.9 13.6 18.9 18.2 3.7 10.3 1.8 18.8 27.3 27.9 2.9 1.0 5.2 13.0 20.4 6.6 2.2 8.6 1.6 8.9 3.1 0.7 3.2 5.5 18.1 1.4 2.0 1.4 19.0 5.0 4.5 6.2 1.3 3.8 5.3 15.8 0.0 0.1 9.5 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 4.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.0 1.2 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 42.0 0.0 0.0 0.0 11.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 15.5 16.1 16.9 17.2 13.6 18.9 18.8 27.3 20.4 18.1 19.0 15.8 13.3 0.0 0.5 10.4 0.0 0.3 0.7 0.0 0.0 2.0 0.4 0.3 0.7 37.1 0.0 9.2 0.0 0.3 0.0 0.0 0.0 0.3 5.9 10.9 3.1 13.2 0.0 2.7 0.6 0.2 0.1 4.9 0.0 3.8 0.0 15.3 17.9 0.0 0.9 1.7 0.5 0.0 0.0 1.3 1.0 1.1 1.5 0.4 0.0 7.5 0.1 12.3 0.0 17.6 0.4 0.1 0.0 4.5 1.4 0.7 0.0 7.7 0.0 1.0 0.0 1.4 1.8 0.6 0.7 0.0 0.4 0.3 0.2 7.2 0.0 0.2 SULT4A1 "hBR-STL-1, SULTX3" ENSG00000130540 "Sulfotransferase family 4A member 1" Q9BR01 22 43824509-43862513 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "brain: 90.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 23.0;Early spermatids: 23.7;Excitatory neurons: 53.1;Horizontal cells: 23.5;Inhibitory neurons: 55.2;Late spermatids: 29.4;Rod photoreceptor cells: 19.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.3" "Region enhanced" "Detected in many" "cerebral cortex: 90.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003129 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA003129: AB_1080130" "unprognostic (2.61e-3)" "unprognostic (1.05e-2)" "unprognostic (2.62e-1)" "unprognostic (6.30e-2)" "unprognostic (6.12e-3)" "unprognostic (1.32e-1)" "unprognostic (1.63e-1)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (2.48e-4)" "unprognostic (1.91e-2)" "unprognostic (6.10e-2)" "unprognostic (7.59e-4)" "unprognostic (7.89e-2)" "unprognostic (1.22e-1)" "unprognostic (8.20e-3)" "unprognostic (8.34e-3)" 0.0 2.7 22.3 0.3 23.2 0.0 0.0 1.6 90.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 22.2 21.7 0.1 0.0 0.0 0.0 9.6 0.0 0.0 0.2 0.0 2.5 0.0 8.0 0.0 0.2 2.2 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.3 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 23.2 1.6 90.2 22.2 21.7 9.6 0.0 8.0 0.0 5.9 25.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.3 0.0 23.0 0.2 0.5 1.4 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 23.7 1.1 1.3 0.4 0.0 0.0 53.1 0.0 0.0 0.4 0.0 3.7 0.0 1.9 0.0 0.0 0.1 23.5 55.2 0.0 0.0 0.0 0.0 29.4 0.0 0.1 0.0 10.3 0.0 4.0 0.0 8.0 6.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.2 19.5 0.0 0.0 0.2 3.0 5.7 0.0 0.0 0.0 0.0 3.2 0.0 0.0 SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 99.8" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 250.0;Alveolar cells type 2: 151.5;Proximal enterocytes: 154.9" "Cancer enhanced" "Detected in all" "testis cancer: 64.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 29 "SK-BR-3: 898.7" "Low region specificity" "Detected in all" HPA004117 Enhanced Approved "Plasma membrane" NA NA 6800000 "Cluster 19: Lung - Lung function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA004117: AB_1857674" "unprognostic (5.24e-3)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-2)" "unprognostic (5.87e-2)" "unprognostic (1.20e-2)" "unprognostic (9.74e-3)" "unprognostic (8.97e-2)" "prognostic unfavorable (3.29e-5)" "unprognostic (2.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.88e-2)" "unprognostic (3.33e-3)" 12.1 9.6 4.9 1.9 2.8 0.2 9.5 1.7 5.8 13.6 2.2 4.8 12.8 9.8 0.5 2.8 15.0 1.8 12.5 1.6 5.3 32.6 2.9 99.8 2.2 22.9 6.9 5.4 4.3 1.5 7.1 3.6 26.5 5.6 1.0 0.1 4.7 5.6 2.2 28.2 34.6 3.4 6.8 3.6 6.3 3.2 13.2 0.8 17.8 1.4 1.3 5.4 11.0 10.0 5.1 10.4 0.1 0.0 18.8 24.3 0.8 2.4 0.1 0.1 0.0 7.8 0.6 1.4 21.5 0.5 0.4 1.4 0.1 0.5 0.0 0.6 0.3 0.0 0.4 30.6 8.0 0.0 0.3 21.5 0.4 0.1 6.2 0.0 0.1 0.0 0.5 0.3 0.0 9.1 0.3 0.4 0.7 2.5 0.3 0.3 0.0 2.5 0.1 0.2 1.7 13.5 0.7 898.7 0.2 3.6 3.0 0.0 0.0 0.1 0.9 0.7 0.1 1.1 1.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 2.8 1.7 5.8 1.6 5.3 22.9 6.9 26.5 6.8 13.2 10.0 1.7 250.0 151.5 0.3 0.6 0.3 0.3 2.6 0.0 0.0 3.4 3.4 6.8 0.0 20.9 1.8 0.0 13.8 0.3 0.7 5.9 0.1 0.0 1.3 0.7 1.1 1.8 0.0 0.2 0.0 0.7 6.7 0.5 1.3 3.8 0.1 2.9 0.5 1.1 0.0 0.1 5.5 2.0 0.0 0.3 0.4 0.6 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.4 154.9 27.8 3.6 0.0 0.0 0.6 22.1 1.7 1.3 0.7 2.7 26.4 1.1 0.0 1.6 0.6 SUSD4 FLJ10052 ENSG00000143502 "Sushi domain containing 4" Q5VX71 1 223220819-223364233 "Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;esophagus: 51.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.7;Inhibitory neurons: 89.7;Oligodendrocyte precursor cells: 101.6;Squamous epithelial cells: 68.3;Theca cells: 65.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 6.8;naive CD4 T-cell: 10.2" "Lineage enriched" "Detected in single" 40 "T-cells: 10.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.7;RPTEC TERT1: 11.1;SCLC-21H: 36.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058296 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA058296: AB_2683672" "unprognostic (2.90e-1)" "unprognostic (2.90e-3)" "unprognostic (1.27e-3)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (7.53e-3)" "unprognostic (1.82e-3)" "unprognostic (7.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-3)" "unprognostic (1.36e-1)" "unprognostic (6.51e-6)" "unprognostic (3.64e-2)" "unprognostic (5.11e-2)" "unprognostic (3.03e-1)" "unprognostic (7.11e-2)" 0.4 6.0 28.4 0.8 21.7 0.4 8.7 5.4 63.7 9.5 0.0 1.3 1.0 0.3 25.1 51.1 3.5 0.7 23.0 69.0 26.8 19.5 3.8 2.8 1.6 9.4 10.4 45.3 10.7 14.9 26.0 0.5 15.9 6.0 0.2 12.2 17.0 4.3 3.5 7.8 0.6 0.4 5.0 0.4 11.0 6.6 21.4 3.4 1.0 2.2 15.0 3.6 25.3 16.2 5.9 0.5 0.2 0.0 0.0 0.0 0.1 0.8 0.4 1.0 0.5 5.8 1.8 0.0 1.8 0.2 0.0 9.7 0.2 1.5 0.9 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.6 0.2 0.0 6.6 0.5 0.0 0.5 3.9 3.8 0.0 0.2 3.0 1.3 0.0 0.2 0.1 11.1 2.8 36.3 0.4 0.0 3.2 0.0 0.8 2.1 0.2 0.0 1.7 6.2 0.0 2.9 0.7 0.1 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.3 0.1 5.5 0.0 6.8 1.7 0.0 0.0 10.2 1.9 0.0 0.2 0.0 0.0 0.9 1.4 28.4 21.7 5.4 63.7 69.0 26.8 9.4 10.4 15.9 5.0 21.4 16.2 0.2 0.0 4.8 6.2 0.0 0.6 8.6 8.4 10.2 17.9 9.7 5.0 9.5 5.7 14.8 16.5 10.4 0.1 0.3 0.1 31.3 0.6 3.1 4.0 0.4 0.6 1.2 0.0 83.7 6.9 0.0 3.8 2.6 6.1 0.0 9.1 0.4 1.8 2.8 21.9 89.7 0.1 2.0 0.6 0.3 3.4 20.5 0.3 5.4 8.4 0.0 1.6 0.0 101.6 2.5 2.6 0.0 12.4 0.1 4.6 0.0 0.3 5.4 6.2 0.0 1.4 2.8 1.3 10.7 68.3 1.7 0.0 1.7 65.5 0.3 25.7 SUSD5 KIAA0527 ENSG00000173705 "Sushi domain containing 5" O60279 3 33150043-33218810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Excitatory neurons: 15.4;Inhibitory neurons: 10.5;Oligodendrocyte precursor cells: 61.3;Sertoli cells: 32.9;Smooth muscle cells: 29.0" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.1;HUVEC TERT2: 78.5;LHCN-M2: 30.4;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052788 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA 17000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "HPA052788: AB_2681948" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-3)" "unprognostic (1.39e-3)" "unprognostic (4.05e-2)" "unprognostic (3.72e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-3)" "unprognostic (6.45e-2)" "unprognostic (8.46e-2)" "unprognostic (1.89e-2)" 4.6 1.4 2.9 0.9 3.0 0.1 1.9 2.2 4.6 6.3 4.4 1.7 0.8 4.6 2.2 1.3 5.2 5.5 1.5 3.1 4.4 1.5 0.5 1.7 2.3 3.4 3.4 3.8 0.6 1.0 0.8 0.2 3.4 1.3 1.2 0.6 0.7 6.3 1.6 1.9 1.9 4.8 3.8 2.5 1.8 2.1 4.7 0.1 3.2 3.3 5.3 1.5 2.4 3.5 0.0 1.1 1.2 0.7 1.7 0.2 0.1 9.6 3.4 31.1 10.5 0.1 0.0 0.0 8.8 2.5 9.5 0.1 13.7 4.5 12.9 0.3 15.3 0.0 2.0 0.0 0.2 0.1 0.1 1.3 2.4 19.9 3.9 15.2 78.5 0.0 0.0 0.1 30.4 0.0 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.0 1.0 0.1 0.1 2.5 0.7 1.8 1.9 31.3 0.0 14.4 1.2 4.7 0.0 0.7 0.0 0.3 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.9 3.0 2.2 4.6 3.1 4.4 3.4 3.4 3.4 3.8 4.7 3.5 0.1 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 2.2 0.5 0.0 0.0 15.4 0.0 0.1 1.4 0.0 0.9 0.0 0.2 0.4 0.0 0.0 3.3 10.5 0.0 0.0 2.1 2.0 0.3 0.0 0.1 1.8 0.0 0.0 0.5 0.0 61.3 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 32.9 3.6 29.0 0.1 2.6 0.1 1.0 0.0 0.2 0.1 0.0 0.1 SYCP2 SCP2 ENSG00000196074 "Synaptonemal complex protein 2" Q9BX26 20 59863564-59933655 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 43.2" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 468.5" "Group enriched" "Detected in many" 6 "breast cancer: 6.7;cervical cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 25.9;JURKAT: 47.2;MOLT-4: 54.4;SiHa: 92.2;T-47d: 82.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA062401, HPA065613" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA062401: AB_2684752, HPA065613: AB_2685519" "unprognostic (8.10e-3)" "unprognostic (8.28e-3)" "unprognostic (1.62e-1)" "unprognostic (2.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.19e-3)" "unprognostic (2.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.11e-2)" "unprognostic (1.44e-1)" "unprognostic (3.74e-1)" "unprognostic (7.02e-3)" "unprognostic (4.84e-3)" "unprognostic (8.48e-2)" "unprognostic (2.46e-1)" "unprognostic (7.87e-3)" "unprognostic (1.21e-1)" 3.2 0.8 2.2 1.4 2.8 2.4 13.9 9.7 4.9 2.4 0.0 1.3 1.6 1.6 1.2 0.9 1.3 2.4 2.5 2.2 1.1 4.3 1.1 2.2 2.6 1.8 1.8 0.7 6.6 0.7 1.9 3.9 2.2 3.8 1.1 1.5 4.4 1.0 1.3 2.7 2.4 0.7 1.4 3.1 6.1 43.2 2.5 1.3 2.4 1.0 1.7 1.8 1.5 4.1 0.3 1.3 0.2 1.4 0.6 0.8 1.4 4.1 1.1 1.8 0.2 25.9 2.6 0.1 4.0 1.8 0.8 0.6 0.5 0.1 1.0 8.5 0.6 0.2 6.1 0.4 0.2 0.4 19.0 0.4 0.4 0.4 0.0 0.9 0.0 47.2 0.2 0.0 0.9 12.5 54.4 2.9 0.4 1.5 0.3 0.0 0.1 0.2 2.1 6.1 0.2 4.5 92.2 13.3 3.3 1.6 82.6 4.7 0.5 0.1 2.8 11.2 0.0 0.0 0.0 0.0 0.0 1.7 5.2 0.7 0.1 0.7 0.8 0.0 0.8 0.2 0.4 0.5 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.0 0.3 0.2 2.2 2.8 9.7 4.9 2.2 1.1 1.8 1.8 2.2 1.4 2.5 4.1 11.5 0.0 1.1 24.5 1.4 1.0 1.1 1.0 0.0 1.9 12.7 9.4 3.6 2.8 6.3 1.8 2.1 0.8 3.0 0.1 1.9 0.9 82.3 0.4 5.0 6.5 0.0 0.0 27.5 3.6 0.4 2.1 2.6 0.5 2.5 1.2 2.9 0.0 0.5 0.0 14.6 0.1 0.0 1.2 0.8 21.8 4.7 1.6 5.4 13.1 1.4 2.3 5.2 28.6 11.1 1.2 1.2 1.9 0.4 1.8 0.3 5.4 8.6 1.1 52.6 1.7 3.8 468.5 92.4 0.6 0.0 0.4 4.1 0.2 0.3 1.2 SYNM "DMN, KIAA0353, SYN" ENSG00000182253 Synemin O15061 15 99098217-99135593 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 594.1;skeletal muscle: 624.7;urinary bladder: 406.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 103.5;Cardiomyocytes: 502.5;Muller glia cells: 127.8;Smooth muscle cells: 98.5" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.8;HeLa: 58.0;WM-115: 124.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017192, HPA040066, HPA044200, HPA077856" Enhanced Supported "Intermediate filaments" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB017192: , HPA040066: AB_2676830, HPA044200: AB_2678854, HPA077856: AB_2686861" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-2)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (1.00e-1)" "unprognostic (1.34e-2)" "unprognostic (6.75e-2)" "unprognostic (3.54e-3)" "unprognostic (2.80e-2)" "unprognostic (7.27e-2)" "unprognostic (5.92e-3)" "unprognostic (3.26e-3)" 37.2 20.3 51.4 26.5 66.0 0.4 56.7 70.1 58.2 11.8 52.5 594.1 27.1 50.8 12.7 169.6 36.5 19.2 144.2 44.4 75.4 6.9 4.8 23.1 4.2 81.7 66.6 14.1 6.3 8.2 23.2 14.0 81.6 150.6 52.0 40.3 25.6 291.3 624.7 17.0 105.7 160.9 71.6 2.9 158.4 5.2 69.3 3.7 11.2 277.1 4.0 406.3 41.0 79.8 6.6 36.8 8.1 21.9 15.9 0.9 0.5 3.7 5.3 2.1 1.3 5.4 4.9 0.0 5.3 5.3 17.7 4.2 5.5 0.1 1.6 0.5 9.0 0.1 58.0 5.4 9.0 0.0 1.0 0.9 0.3 3.7 0.8 6.0 4.3 0.0 0.2 7.4 5.5 3.7 0.7 0.8 7.2 0.7 11.4 0.0 7.5 5.5 2.1 3.6 3.6 4.2 21.9 3.4 13.5 12.7 0.2 3.6 4.8 4.1 0.4 2.9 8.9 0.1 1.0 0.0 0.4 0.0 124.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 51.4 66.0 70.1 58.2 44.4 75.4 81.7 66.6 81.6 71.6 69.3 79.8 14.8 0.0 1.7 15.3 0.9 2.3 0.7 0.9 2.8 12.6 32.7 103.5 502.5 0.0 1.2 0.0 16.7 1.5 6.6 2.1 0.0 0.5 9.5 1.3 1.0 24.2 3.0 0.0 15.6 1.3 0.7 20.3 5.1 4.2 0.0 1.1 3.6 1.3 0.3 42.1 9.8 0.9 0.0 0.0 5.1 4.5 1.2 2.0 5.4 12.2 0.6 127.8 1.0 2.5 14.0 0.2 2.3 4.1 5.4 2.0 0.6 0.3 3.1 10.2 32.9 19.6 98.5 7.9 11.5 2.1 3.7 0.4 5.9 0.2 0.7 0.9 SYPL2 Mg29 ENSG00000143028 "Synaptophysin like 2" Q5VXT5 1 109466546-109482134 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "skeletal muscle: 363.5;tongue: 175.3" "Cell type enhanced" "Detected in some" "Astrocytes: 5.5;Cardiomyocytes: 10.6;Collecting duct cells: 3.7;Hepatocytes: 4.8;Late spermatids: 11.1;Proximal tubular cells: 5.1;Skeletal myocytes: 4.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.2;BJ: 14.1;BJ hTERT+: 44.1;fHDF/TERT166: 23.1;HAP1: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076657 Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA076657: " "unprognostic (1.82e-2)" "unprognostic (1.81e-1)" "unprognostic (2.90e-4)" "unprognostic (6.63e-2)" "unprognostic (1.35e-1)" "unprognostic (9.36e-3)" "unprognostic (2.84e-2)" "unprognostic (2.57e-1)" "unprognostic (2.35e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "prognostic favorable (3.05e-4)" "unprognostic (2.54e-3)" "unprognostic (3.40e-1)" "unprognostic (9.46e-3)" "unprognostic (6.39e-4)" 2.8 11.7 1.5 0.6 1.5 0.0 1.5 1.3 2.4 4.0 4.0 6.2 0.5 6.6 4.5 4.6 1.4 0.9 19.9 1.6 1.3 9.6 9.5 1.3 0.5 1.4 1.3 3.0 5.1 5.8 1.1 3.2 1.2 3.1 1.0 0.4 4.2 6.0 363.5 0.7 1.6 6.0 1.0 1.1 3.2 9.3 1.6 0.1 8.0 175.3 0.3 4.1 2.4 1.3 0.0 0.1 0.1 1.8 31.6 13.2 0.0 14.1 44.1 4.3 1.6 0.0 0.1 0.0 0.0 23.1 0.5 0.0 11.8 0.0 0.9 0.0 5.1 0.0 0.4 0.2 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.1 0.1 0.0 1.4 3.3 2.3 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.5 1.3 2.4 1.6 1.3 1.4 1.3 1.2 1.0 1.6 1.3 0.2 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 10.6 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.2 2.8 0.0 0.1 0.4 0.0 0.0 0.3 1.3 0.0 1.0 0.0 0.0 0.0 0.9 0.0 4.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.1 0.0 5.1 0.0 0.0 0.0 4.8 2.6 0.4 1.4 0.0 0.0 0.1 0.2 0.4 0.0 0.0 SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 336.8" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.1;NTERA-2: 8.8;RPTEC TERT1: 56.8;SCLC-21H: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" 0.1 4.7 7.0 1.5 12.7 0.0 0.2 1.7 30.1 0.0 0.0 12.2 12.5 0.2 0.0 0.0 0.2 20.8 5.2 18.0 11.5 8.9 0.3 0.5 0.0 5.7 1.2 0.0 7.1 0.4 16.8 0.0 5.4 1.8 12.6 11.3 1.9 0.0 0.1 0.2 12.8 0.8 0.0 0.1 11.0 1.7 9.0 0.3 1.6 0.1 0.0 0.0 0.0 5.2 0.0 19.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 8.8 0.0 0.2 0.0 0.0 0.0 56.8 0.0 15.0 0.7 0.0 0.0 0.1 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 12.7 1.7 30.1 18.0 11.5 5.7 1.2 5.4 0.0 9.0 5.2 0.0 0.0 0.0 4.6 0.1 0.0 0.2 0.0 0.0 3.3 0.1 0.3 15.3 17.2 0.0 3.7 25.0 0.0 0.0 10.2 5.9 1.2 3.1 0.4 0.2 0.1 336.8 0.0 41.6 0.6 0.0 1.7 3.6 2.0 0.0 2.5 0.0 0.0 0.0 1.7 43.8 37.3 4.1 0.0 0.0 9.7 0.3 0.0 0.0 5.6 0.0 0.7 0.0 1.5 3.5 8.2 14.3 0.0 0.0 2.3 13.9 0.5 0.0 2.7 0.0 0.0 0.2 2.0 0.2 0.0 0.0 0.0 0.0 0.0 32.8 0.2 SYT8 DKFZp434K0322 ENSG00000149043 "Synaptotagmin 8" Q8NBV8 11 1828307-1837521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.2;skin 1: 65.5;urinary bladder: 40.5" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 184.7;Basal squamous epithelial cells: 520.2;Breast myoepithelial cells: 192.9;Cholangiocytes: 183.0;Extravillous trophoblasts: 201.8;Respiratory ciliated cells: 163.8;Squamous epithelial cells: 132.5" "Group enriched" "Detected in many" 5 "cervical cancer: 10.5;pancreatic cancer: 21.7;urothelial cancer: 33.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CAPAN-2: 32.2;hTCEpi: 50.2;T-47d: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047239, HPA052700" Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA047239: , HPA052700: AB_2681920" "unprognostic (1.66e-3)" "unprognostic (2.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.14e-1)" "unprognostic (6.31e-2)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (1.36e-2)" "unprognostic (1.02e-1)" "unprognostic (8.25e-2)" "unprognostic (7.09e-2)" "unprognostic (2.48e-1)" "unprognostic (2.33e-6)" "unprognostic (2.87e-2)" "unprognostic (1.75e-1)" "unprognostic (5.52e-2)" "unprognostic (2.77e-2)" 0.1 0.2 0.0 0.0 0.0 0.0 5.1 0.0 0.0 1.3 0.1 0.4 0.5 0.0 0.5 29.2 1.0 8.6 0.0 0.0 0.0 0.3 0.6 4.7 0.0 0.0 0.0 0.0 14.9 0.0 0.2 1.6 0.0 2.5 0.0 0.0 20.9 2.9 0.0 65.5 2.5 0.0 0.0 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.1 40.5 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 32.2 0.0 0.0 0.0 0.6 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 50.2 0.0 5.8 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 5.7 0.0 0.0 0.3 0.0 0.1 1.0 0.0 0.3 0.0 2.7 0.0 0.0 13.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 16.0 3.9 0.0 0.3 184.7 5.6 24.9 520.2 0.0 3.2 192.9 0.6 183.0 39.1 5.5 0.0 28.7 0.7 3.4 0.0 31.1 0.0 15.6 0.1 1.7 0.0 0.0 0.0 9.7 201.8 1.6 12.2 0.6 1.3 0.0 0.0 0.1 7.1 0.0 0.0 1.3 16.2 0.0 14.7 0.0 0.0 1.3 10.6 0.0 0.0 0.0 0.0 0.0 0.0 28.3 3.5 0.0 6.2 1.3 18.3 0.0 163.8 0.0 0.0 0.0 7.0 0.0 0.0 132.5 47.2 36.8 0.6 0.1 1.7 31.5 SYT9 ENSG00000170743 "Synaptotagmin 9" Q86SS6 11 7238778-7469043 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9;retina: 7.6" "Cell type enhanced" "Detected in some" "Astrocytes: 48.6;Late spermatids: 23.5;Oligodendrocyte precursor cells: 55.3;Oligodendrocytes: 139.2" "Cancer enhanced" "Detected in some" "breast cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEK 293: 10.3;RT4: 17.9;SH-SY5Y: 13.2;TIME: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.47e-1)" "unprognostic (9.41e-2)" "unprognostic (1.39e-5)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (5.50e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.67e-2)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (3.31e-3)" "unprognostic (4.35e-2)" "unprognostic (1.92e-4)" "unprognostic (1.22e-4)" 0.0 2.0 9.1 0.0 9.2 0.0 0.8 11.7 5.9 0.4 1.4 0.1 0.0 1.2 0.0 0.0 0.1 0.1 0.3 4.7 7.6 2.0 3.6 0.0 0.0 9.9 11.8 0.1 1.3 0.9 1.5 0.0 9.6 1.0 0.0 7.6 0.0 3.6 0.0 0.1 0.1 0.1 8.1 0.0 0.1 0.9 15.9 0.0 1.1 0.0 0.0 0.2 0.3 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.5 0.0 0.0 0.0 0.0 17.9 3.2 13.2 0.0 0.0 0.0 0.4 0.0 0.0 20.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 9.2 11.7 5.9 4.7 7.6 9.9 11.8 9.6 8.1 15.9 11.7 0.0 0.0 0.0 48.6 0.5 0.0 0.1 0.0 0.0 13.6 0.7 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 13.9 0.0 0.2 0.0 0.0 0.0 15.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.2 0.0 3.3 9.8 0.0 0.0 0.3 0.0 23.5 0.0 0.0 0.0 5.6 0.0 2.0 0.0 55.3 139.2 0.0 0.0 0.0 0.0 0.2 0.0 1.5 0.0 3.5 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SYTL1 "exophilin-7, FLJ14996, JFC1, SLP1" ENSG00000142765 "Synaptotagmin like 1" Q8IYJ3 1 27342020-27353937 "Plasma proteins, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 103.9;pancreas: 106.3;skin 1: 87.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 158.8;NK-cells: 208.1;Squamous epithelial cells: 179.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 4.3;cerebellum: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 47.8;CAPAN-2: 55.8;NB-4: 81.8;U-266/70: 44.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA037825 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA037825: AB_10671635" "unprognostic (4.23e-2)" "unprognostic (8.23e-2)" "unprognostic (2.40e-1)" "prognostic favorable (6.83e-7)" "unprognostic (7.81e-3)" "unprognostic (5.81e-2)" "unprognostic (1.05e-1)" "unprognostic (7.18e-3)" "unprognostic (4.41e-1)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (1.45e-1)" "unprognostic (3.02e-1)" "unprognostic (1.72e-2)" "unprognostic (5.88e-3)" 2.0 0.6 4.3 19.1 0.7 46.7 7.7 8.8 1.4 22.6 6.1 6.7 7.8 1.3 1.2 103.9 15.5 8.6 0.9 1.0 1.0 2.8 2.1 13.1 32.9 0.7 0.8 0.6 106.3 4.2 15.6 2.9 0.8 63.6 3.3 0.0 47.6 12.7 0.5 87.2 17.6 0.4 0.5 42.0 41.8 0.9 1.2 21.4 9.8 0.5 20.0 21.6 50.9 0.6 11.3 0.2 0.0 0.4 0.0 0.0 47.8 0.0 0.0 0.0 0.0 1.2 55.8 8.5 10.9 0.0 0.3 34.7 0.0 21.0 0.0 0.0 2.1 1.0 0.9 15.3 0.8 21.9 0.0 0.0 37.8 0.0 7.8 0.2 0.0 28.2 0.7 9.5 0.0 15.5 12.9 81.8 0.5 19.1 5.7 14.9 0.1 40.2 8.6 9.6 15.9 0.9 0.0 15.9 0.6 0.5 40.4 23.3 0.2 0.1 5.1 0.0 0.0 44.3 11.7 8.0 1.6 27.7 0.0 47.0 18.9 176.5 65.0 49.1 58.4 42.8 51.5 53.2 51.0 32.3 30.6 37.3 34.1 49.0 100.8 3.0 63.4 40.0 4.3 0.7 8.8 1.4 1.0 1.0 0.7 0.8 0.8 0.5 1.2 0.6 1.9 22.4 13.6 0.0 68.6 41.2 78.2 84.4 158.8 0.6 33.6 49.8 3.9 8.6 69.2 0.0 0.0 37.4 92.3 4.8 7.9 3.7 0.8 67.8 2.4 2.3 11.4 15.8 0.3 25.5 10.1 3.1 100.9 18.3 1.3 0.2 2.2 1.1 3.2 0.0 0.3 47.6 32.6 6.7 12.7 0.7 0.3 15.7 10.6 0.0 18.8 2.0 208.1 0.0 0.1 12.1 3.7 0.7 52.3 46.8 3.1 6.4 62.8 0.8 0.0 1.3 5.6 30.3 23.1 179.1 55.3 14.1 74.9 0.2 9.4 95.3 TACC2 "AZU-1, ECTACC" ENSG00000138162 "Transforming acidic coiled-coil containing protein 2" O95359 10 121989163-122254545 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 251.7;skeletal muscle: 387.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 210.1;Syncytiotrophoblasts: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031020, HPA031021, HPA061394" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 32000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA031020: AB_10669988, HPA031021: AB_2673701, HPA061394: AB_2684500" "unprognostic (3.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.75e-2)" "unprognostic (7.07e-2)" "unprognostic (2.26e-1)" "unprognostic (1.14e-1)" "unprognostic (9.15e-2)" "unprognostic (8.43e-3)" "unprognostic (1.14e-1)" "unprognostic (3.51e-1)" "unprognostic (2.13e-1)" "unprognostic (1.83e-2)" "prognostic favorable (2.50e-10)" "unprognostic (7.02e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (1.61e-1)" 22.1 15.3 18.2 5.3 18.6 0.2 20.9 23.6 22.7 32.3 28.6 91.5 15.3 26.1 9.2 64.2 32.9 12.9 251.7 19.1 18.8 33.9 18.8 68.7 1.0 16.0 16.9 8.8 25.3 36.4 58.7 21.6 14.8 67.7 20.7 7.2 60.7 13.5 387.1 103.3 35.7 22.0 11.8 4.2 49.1 5.8 16.9 5.7 50.7 159.0 5.7 62.4 49.1 17.7 17.8 55.1 26.5 15.2 7.4 7.4 31.7 7.7 20.7 10.5 7.3 22.7 28.9 0.0 7.0 12.3 12.1 58.1 8.5 20.9 10.9 3.0 4.4 0.0 7.7 43.8 11.5 0.0 0.3 3.4 86.0 5.6 36.6 8.6 22.2 0.1 4.5 0.6 10.4 23.5 0.2 9.9 15.7 27.6 24.8 0.3 15.2 8.5 28.9 26.9 17.6 14.2 12.7 52.0 29.5 7.6 10.2 0.4 20.6 4.7 3.5 11.8 14.5 2.4 11.7 0.3 8.7 0.1 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 18.6 23.6 22.7 19.1 18.8 16.0 16.9 14.8 11.8 16.9 17.7 15.5 83.3 94.1 16.3 0.7 33.6 49.7 54.3 33.0 21.6 23.4 14.1 210.1 8.6 70.7 36.8 0.0 53.3 0.4 75.2 1.9 8.2 2.4 88.4 11.0 21.3 30.0 0.0 32.8 14.2 4.4 21.2 38.7 62.8 7.0 0.1 6.1 18.9 6.5 43.7 48.2 38.8 57.0 0.3 4.3 2.6 6.8 1.9 7.2 7.5 0.1 1.1 0.0 80.9 7.6 19.4 47.1 7.5 0.2 49.6 36.5 13.5 84.9 2.7 13.1 27.2 23.7 0.5 8.2 79.5 54.0 228.5 2.6 2.8 41.9 80.5 TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712891-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.9;lymphoid tissue: 52.4;testis: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 43.9;Late spermatids: 69.9;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 5.3 3.9 4.2 24.9 4.3 58.9 3.5 5.2 5.3 3.6 5.2 10.3 6.6 3.3 4.8 14.9 2.8 4.2 3.3 4.5 4.4 2.7 3.5 6.5 43.2 4.8 5.3 2.2 1.4 2.3 2.6 8.7 4.8 2.4 10.6 1.9 3.9 2.5 2.0 6.4 12.9 6.4 4.2 22.1 6.4 50.6 5.1 52.4 2.8 3.4 39.3 5.0 5.4 4.7 106.7 88.7 129.5 72.2 6.7 15.2 72.9 114.6 62.1 135.4 87.6 93.5 122.8 133.8 48.0 65.4 149.9 71.4 142.5 86.8 131.1 59.8 77.0 113.8 67.2 85.8 5.9 146.6 85.5 5.2 5.7 85.6 46.0 26.0 102.2 110.3 106.3 90.8 123.8 87.1 207.5 204.0 139.3 89.2 111.6 139.1 90.5 55.0 73.8 125.5 99.8 62.8 70.1 42.3 33.1 95.2 83.3 90.5 56.4 75.4 90.0 65.4 176.7 69.5 102.5 207.1 43.2 141.1 109.1 45.5 30.0 37.9 8.5 12.5 11.1 7.8 16.5 11.5 15.3 10.8 28.3 13.1 91.8 12.2 9.6 8.3 42.5 32.5 4.2 4.3 5.2 5.3 4.5 4.4 4.8 5.3 4.8 4.2 5.1 4.7 6.0 0.0 6.7 2.0 16.5 2.2 1.2 3.2 1.2 1.7 2.4 3.0 2.6 2.8 3.4 9.2 8.4 19.5 6.4 11.2 0.0 2.2 70.4 4.2 2.8 5.2 1.2 37.2 2.3 0.7 20.4 6.0 12.8 4.3 5.1 24.5 8.9 5.1 43.9 5.0 3.2 9.5 4.1 23.2 10.8 69.9 2.8 34.1 0.0 4.7 24.4 1.4 6.2 0.5 0.8 2.9 4.2 2.6 18.0 1.3 2.6 2.8 0.9 2.7 6.6 2.0 4.8 94.3 37.7 12.8 1.4 4.0 23.2 2.2 16.1 2.7 TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 7 "Inhibitory neurons: 83.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA074573: AB_2686701" "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" 6.2 0.3 1.7 0.7 3.6 0.0 5.0 0.0 7.2 4.9 0.0 1.0 0.2 3.0 0.7 1.2 2.9 1.1 0.1 0.6 3.7 0.7 0.0 0.8 1.3 2.2 4.3 0.6 0.1 0.2 0.1 0.5 10.0 1.5 0.5 1.0 1.5 1.0 0.3 4.0 0.7 2.7 0.8 0.0 0.5 0.0 2.5 1.1 0.5 0.3 1.3 2.0 2.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.6 0.0 7.2 0.6 3.7 2.2 4.3 10.0 0.8 2.5 0.9 7.6 0.0 0.0 1.0 0.0 2.5 0.0 0.0 0.0 1.0 0.3 0.3 1.4 0.0 0.0 0.0 2.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 11.8 0.0 0.0 4.5 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 83.2 0.2 0.0 0.0 2.6 0.9 0.0 0.0 7.2 2.8 0.0 0.4 0.0 3.5 4.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 3.3 0.0 0.2 0.2 0.0 0.0 0.1 1.8 0.1 0.1 0.0 0.0 0.2 TAF4B "TAF2C2, TAFII105" ENSG00000141384 "TATA-box binding protein associated factor 4b" Q92750 18 26226445-26391685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 80.3;Plasma cells: 52.3;Suprabasal keratinocytes: 78.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 65.0;U-266/70: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028937 Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - Translation" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA028937: AB_10603034" "unprognostic (2.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-3)" "unprognostic (1.74e-1)" "unprognostic (2.13e-1)" "unprognostic (5.01e-2)" "unprognostic (2.67e-1)" "unprognostic (3.29e-2)" "unprognostic (2.21e-1)" "unprognostic (4.66e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (7.38e-2)" "unprognostic (9.56e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.72e-4)" 1.5 2.0 0.4 2.8 0.4 2.8 2.7 0.3 1.9 1.2 0.0 1.6 0.4 1.4 0.3 1.0 1.3 0.7 0.4 0.3 0.2 1.5 0.1 1.0 3.1 0.9 0.1 3.1 1.2 0.6 0.2 1.7 1.1 0.8 1.4 0.3 1.1 0.8 1.3 1.5 0.8 1.2 0.0 2.5 1.8 4.6 0.2 1.8 1.7 0.7 3.2 1.5 0.6 0.8 4.3 0.7 0.3 1.1 1.6 2.6 2.1 1.3 1.5 0.7 1.3 1.1 2.3 65.0 5.0 0.3 2.5 4.8 3.7 4.0 3.4 15.5 9.9 7.5 1.9 1.0 2.3 20.5 4.4 4.3 1.5 0.5 11.6 0.6 1.4 8.1 10.2 7.9 0.3 4.2 10.7 4.1 3.5 2.5 5.1 0.0 8.1 17.3 1.0 0.3 6.1 2.8 3.9 5.7 2.7 1.6 2.0 3.6 0.9 2.7 1.6 3.7 4.8 26.2 18.0 21.8 1.3 12.8 2.4 0.0 0.3 0.0 0.1 0.5 1.0 2.3 0.7 1.0 1.0 2.0 2.0 1.6 0.0 0.6 0.2 0.3 0.1 0.6 0.4 0.4 0.3 1.9 0.3 0.2 0.9 0.1 1.1 0.0 0.2 0.8 7.2 6.4 7.2 6.2 34.0 80.3 9.5 1.7 49.5 1.5 15.0 17.9 2.8 0.0 2.5 0.0 0.0 18.6 4.1 5.8 17.6 1.2 0.7 28.9 9.7 9.0 0.0 21.7 44.8 2.0 4.3 15.5 36.7 45.0 1.3 5.4 1.1 0.0 2.4 5.0 28.3 7.0 2.0 1.6 17.9 1.6 3.4 5.9 23.2 4.7 2.6 0.2 1.0 7.5 11.7 2.2 2.5 4.1 52.3 13.9 0.8 4.0 1.0 1.2 0.0 17.6 12.1 25.4 24.8 40.8 78.8 9.7 14.5 14.5 6.2 6.7 TAFA5 "FAM19A5, TAFA-5" ENSG00000219438 "TAFA chemokine like family member 5" Q7Z5A7 22 48489553-48850912 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 85.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Fibroblasts: 1.1" "Cancer enhanced" "Detected in all" "glioma: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 17.3;HEK 293: 13.6;Hep G2: 32.1;NTERA-2: 12.7;U-2 OS: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025629 Approved "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB025629: " "unprognostic (2.86e-1)" "unprognostic (2.98e-1)" "unprognostic (3.42e-2)" "unprognostic (2.19e-1)" "unprognostic (3.57e-1)" "unprognostic (1.80e-1)" "unprognostic (2.82e-3)" "unprognostic (2.41e-2)" "unprognostic (6.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-2)" "unprognostic (1.26e-1)" "unprognostic (9.31e-3)" "unprognostic (2.64e-2)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.94e-2)" 2.7 1.3 50.3 0.8 40.6 0.0 2.0 37.0 51.8 19.7 15.0 8.4 1.0 8.1 4.7 0.9 5.2 2.0 2.5 53.9 43.0 2.4 2.7 2.1 0.4 55.2 85.9 12.1 2.4 4.3 7.0 0.1 51.1 6.8 0.2 3.6 4.9 3.2 1.5 5.4 3.3 0.7 41.5 0.3 2.9 3.3 49.6 1.2 0.8 1.7 0.1 4.0 4.9 28.2 0.0 1.3 2.5 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 17.3 0.1 0.1 1.3 0.0 0.0 0.0 13.6 0.0 0.2 32.1 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.3 12.7 0.6 0.0 0.6 0.0 7.4 0.0 0.0 7.2 0.2 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 40.6 37.0 51.8 53.9 43.0 55.2 85.9 51.1 41.5 49.6 28.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TAP1 "ABCB2, D6S114E, PSF1, RING4" ENSG00000168394 "Transporter 1, ATP binding cassette subfamily B member" Q03518 6 32845209-32853816 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 126.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009516, HPA072354" Approved Approved "Endoplasmic reticulum,Centriolar satellite" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum, Centriolar satellite" "CAB009516: AB_2303048, HPA072354: AB_2686513" "unprognostic (3.59e-2)" "unprognostic (1.06e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.22e-2)" "unprognostic (4.92e-2)" "unprognostic (6.16e-3)" "unprognostic (2.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (3.02e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (6.58e-5)" "unprognostic (2.07e-2)" "unprognostic (4.69e-2)" "unprognostic (2.42e-2)" "unprognostic (2.21e-2)" 28.4 24.9 16.1 50.1 16.2 13.7 20.7 15.8 20.3 21.6 16.2 30.3 36.0 20.5 2.5 31.6 17.8 12.7 25.4 14.7 16.2 21.8 19.3 52.7 50.0 24.0 16.1 12.1 14.5 7.0 11.6 12.1 21.2 21.9 12.5 1.7 25.9 7.0 16.3 51.2 42.6 11.5 18.6 73.0 33.4 11.5 19.4 25.5 17.0 7.4 21.3 23.9 24.4 17.4 22.9 13.7 0.1 16.1 8.8 11.4 126.2 8.1 34.3 59.3 86.5 2.0 27.3 41.8 25.0 12.6 48.9 45.8 4.5 20.6 5.3 81.0 6.1 26.5 4.1 10.8 42.3 0.1 17.5 15.0 17.9 17.1 10.4 8.6 15.4 8.4 1.9 55.0 10.6 10.5 17.7 27.4 0.8 3.1 11.1 47.6 5.2 32.8 25.0 10.5 0.2 1.2 6.7 38.0 33.4 1.7 30.9 37.4 9.7 21.5 8.1 53.1 11.4 59.9 82.6 12.6 16.6 16.6 16.4 176.8 99.5 270.1 155.8 101.6 133.8 137.3 125.2 153.7 95.0 107.5 120.9 124.6 295.6 132.9 94.6 94.8 213.8 221.2 16.1 16.2 15.8 20.3 14.7 16.2 24.0 16.1 21.2 18.6 19.4 17.4 72.1 25.6 24.0 9.1 62.1 74.7 47.1 54.5 27.3 4.8 21.5 15.9 7.3 24.3 33.1 5.5 0.0 5.6 108.0 78.8 5.9 81.6 0.5 31.3 39.3 63.6 16.8 12.6 1.1 75.3 95.0 26.9 42.8 77.9 26.6 13.8 27.1 11.1 45.9 15.2 1.9 55.9 57.0 31.9 90.6 0.3 13.1 43.9 23.2 16.9 115.9 25.1 149.3 12.1 3.6 91.3 38.8 10.5 84.8 70.2 84.6 6.9 29.4 2.8 6.6 18.1 27.8 1.0 1.3 20.4 76.4 4.8 92.3 18.2 54.5 52.1 TBC1D2 "Armus, PARIS1, TBC1D2A" ENSG00000095383 "TBC1 domain family member 2" Q9BYX2 9 98199011-98255649 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 77.0;HaCaT: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030871, HPA076521" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA030871: AB_10670046, HPA076521: " "unprognostic (2.32e-2)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.86e-1)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (9.21e-3)" "unprognostic (6.40e-3)" "unprognostic (2.30e-1)" "unprognostic (6.07e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.30e-2)" "unprognostic (4.30e-1)" 8.8 5.3 11.1 5.7 16.0 13.1 7.8 12.3 26.0 10.8 8.5 8.6 12.6 4.4 1.5 37.4 5.5 4.0 3.7 10.6 12.9 6.4 19.8 32.0 3.8 14.9 14.9 2.9 3.0 3.5 4.4 7.2 16.4 12.0 4.4 3.4 14.7 6.1 4.3 24.3 10.1 2.8 11.4 9.4 7.0 3.4 23.3 3.0 8.1 1.4 4.9 11.7 17.3 23.9 77.0 10.8 0.5 2.5 8.2 15.9 24.3 33.2 18.4 23.8 19.6 6.9 32.8 1.3 24.7 19.6 5.2 98.1 0.7 36.8 8.3 2.6 1.4 0.7 38.0 5.4 37.6 1.7 2.9 21.7 59.8 23.6 58.7 41.5 8.6 2.1 2.4 1.0 19.0 9.9 0.4 4.6 1.6 7.4 6.2 1.2 4.8 0.2 36.0 46.7 0.9 1.4 11.3 24.4 3.4 1.7 8.1 2.6 51.7 28.8 8.6 4.8 13.6 1.6 1.5 0.6 29.0 2.9 3.2 2.1 27.5 8.4 2.5 15.3 1.8 1.2 3.8 2.2 10.0 0.8 1.6 1.9 11.9 1.2 12.3 1.3 5.5 10.8 11.1 16.0 12.3 26.0 10.6 12.9 14.9 14.9 16.4 11.4 23.3 23.9 2.9 57.7 12.5 5.2 2.4 8.3 18.5 30.4 21.6 3.3 2.7 5.6 0.7 4.3 23.3 3.7 0.0 21.5 0.9 16.2 3.9 3.3 1.8 4.6 3.7 5.0 7.7 0.4 4.6 3.2 10.9 2.4 6.1 10.3 0.0 0.6 1.1 6.1 32.0 1.7 5.4 12.6 18.3 16.2 1.8 1.2 1.8 18.3 3.6 4.7 7.5 4.4 3.1 12.1 64.9 14.4 10.7 0.7 1.7 9.2 16.4 3.2 10.8 2.4 0.0 1.8 3.4 2.1 3.0 29.8 10.9 17.4 2.4 0.7 5.7 17.1 TBC1D22B "C6orf197, dJ744I24.2, FLJ20337" ENSG00000065491 "TBC1 domain family member 22B" Q9NU19 6 37257772-37332970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 80.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027908, HPA027909, HPA027910" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA027908: AB_10602073, HPA027909: AB_10601857, HPA027910: AB_10602203" "unprognostic (9.83e-2)" "unprognostic (5.36e-2)" "unprognostic (2.17e-2)" "prognostic unfavorable (8.15e-5)" "unprognostic (2.70e-1)" "unprognostic (1.45e-1)" "unprognostic (2.29e-2)" "unprognostic (1.44e-1)" "unprognostic (9.48e-2)" "unprognostic (6.06e-3)" "unprognostic (3.10e-2)" "unprognostic (1.46e-1)" "unprognostic (3.53e-3)" "unprognostic (9.87e-2)" "unprognostic (2.71e-1)" "unprognostic (3.19e-1)" "unprognostic (9.73e-2)" 5.8 12.1 8.3 5.1 8.4 18.3 5.7 8.3 8.2 7.9 8.8 6.5 7.9 6.4 7.4 14.1 8.2 5.9 7.4 8.3 8.0 8.6 6.1 8.0 5.8 7.7 8.1 9.4 12.8 10.7 6.7 6.0 7.9 8.2 7.7 7.7 11.8 5.5 15.0 15.2 8.5 6.7 7.1 7.2 7.5 10.0 8.5 13.5 7.7 7.8 7.1 7.5 9.3 8.1 13.2 5.5 9.9 10.9 9.1 9.1 14.2 7.2 15.0 13.2 16.2 12.6 8.5 12.3 7.4 9.2 17.9 8.9 12.7 11.6 14.8 19.9 10.4 19.5 9.0 17.2 13.0 11.1 15.9 7.8 16.6 13.0 15.4 12.6 18.9 20.4 22.5 3.1 9.6 11.9 16.6 8.4 13.0 15.0 5.1 10.7 9.1 9.6 13.6 9.5 13.0 8.4 7.9 11.2 14.3 13.3 8.2 19.7 18.4 8.0 12.2 5.5 9.6 11.1 12.4 80.8 5.5 16.5 12.6 1.4 2.6 4.4 2.3 3.5 2.7 1.7 2.6 2.3 4.0 2.0 2.8 2.4 1.1 3.0 1.5 1.1 1.9 2.6 8.3 8.4 8.3 8.2 8.3 8.0 7.7 8.1 7.9 7.1 8.5 8.1 4.1 3.2 5.6 17.9 6.3 8.2 8.5 7.5 8.0 5.0 6.0 3.7 5.8 7.2 10.1 1.8 4.2 6.3 4.6 15.1 3.9 12.3 5.6 10.6 3.6 4.9 1.8 10.5 20.3 15.4 9.2 4.2 3.1 8.1 5.7 5.0 3.6 3.9 5.8 0.0 22.0 4.9 10.2 4.4 7.8 5.0 3.1 4.1 1.8 6.5 6.0 3.6 6.2 14.1 24.1 15.0 6.8 1.2 5.6 10.0 11.2 9.0 15.8 4.5 0.0 4.2 3.6 6.5 6.4 10.8 15.9 6.7 6.6 3.2 6.3 11.2 TBC1D31 "Gm85, MGC21654, WDR67" ENSG00000156787 "TBC1 domain family member 31" Q96DN5 8 123041968-123152153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.6" "Cell type enhanced" "Detected in many" "Astrocytes: 19.9;Excitatory neurons: 23.4;Inhibitory neurons: 32.0;NK-cells: 24.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 83.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023710 Approved Approved Centrosome NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA023710: AB_1858819" "unprognostic (1.39e-1)" "unprognostic (5.44e-3)" "unprognostic (7.21e-2)" "unprognostic (3.18e-5)" "unprognostic (2.42e-1)" "unprognostic (8.98e-2)" "unprognostic (2.63e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.53e-2)" "unprognostic (6.59e-2)" "unprognostic (8.88e-2)" "unprognostic (1.13e-1)" "unprognostic (1.18e-4)" "unprognostic (1.78e-3)" "unprognostic (1.57e-1)" "unprognostic (1.76e-2)" "unprognostic (2.33e-1)" 3.9 2.5 5.8 6.0 7.8 7.4 2.0 20.6 6.6 1.7 5.2 4.2 5.4 2.4 1.4 2.5 4.2 2.2 2.7 7.3 4.1 2.8 3.1 2.5 7.2 4.3 5.5 1.7 3.8 2.9 3.5 1.9 5.1 2.3 3.5 4.9 2.4 1.7 4.4 2.9 4.8 2.7 4.4 5.8 3.4 5.1 6.0 14.4 3.1 2.5 6.1 2.2 1.7 7.3 30.6 19.5 15.4 12.9 5.1 5.5 10.9 17.5 6.4 14.0 12.7 17.9 11.4 11.2 21.5 4.7 9.5 21.1 14.3 7.2 19.7 31.3 31.6 28.8 13.5 8.3 7.7 11.9 20.3 4.4 4.2 11.6 11.9 4.1 10.2 31.0 24.0 23.1 10.2 50.5 37.2 8.1 12.8 26.5 29.8 21.2 14.5 16.8 9.4 11.1 16.8 14.7 31.5 83.2 9.7 9.8 15.8 9.2 8.8 12.8 31.9 11.9 22.1 34.5 58.1 15.1 13.2 20.1 19.0 9.1 10.0 10.6 17.4 12.6 26.6 9.2 10.6 14.3 8.8 8.4 10.8 12.3 5.8 20.5 11.2 7.9 11.6 15.6 5.8 7.8 20.6 6.6 7.3 4.1 4.3 5.5 5.1 4.4 6.0 7.3 2.7 0.0 3.4 19.9 3.7 0.5 1.0 2.4 1.2 2.7 1.0 1.3 14.0 0.0 1.4 1.8 6.2 1.6 10.4 2.4 0.0 1.8 4.9 3.4 3.2 2.4 3.0 12.8 23.4 1.1 2.6 2.6 2.6 1.2 7.6 4.2 1.1 1.8 3.9 0.0 32.0 2.0 0.0 6.6 1.9 2.9 1.5 3.8 1.8 14.0 4.6 1.3 24.7 11.1 13.4 1.0 0.6 1.5 5.8 0.7 1.2 2.2 3.7 5.9 0.0 2.4 2.3 10.9 2.7 4.1 1.3 0.1 12.5 2.5 3.5 0.6 TBX21 "T-bet, TBLYM" ENSG00000073861 "T-box transcription factor 21" Q9UL17 17 47733236-47746122 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.1;lung: 3.3;lymphoid tissue: 11.7" "Cell type enhanced" "Detected in some" "dendritic cells: 92.8;NK-cells: 119.4;Plasma cells: 22.8;T-cells: 45.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 15.7;NK-cell: 14.3" "Group enriched" "Detected in many" 7 "NK-cells: 14.3;T-cells: 15.7" "Cell line enriched" "Detected in single" 113 "HDLM-2: 16.3" "Region enriched" "Detected in single" 27 "olfactory bulb: 22.1" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.2" "CAB009524, CAB030043" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB009524: AB_2200557, CAB030043: AB_1595503" "unprognostic (3.31e-3)" "unprognostic (3.17e-3)" "unprognostic (1.17e-2)" "unprognostic (5.35e-6)" "unprognostic (3.93e-1)" "unprognostic (2.56e-4)" "unprognostic (5.86e-4)" "unprognostic (6.90e-2)" "unprognostic (3.63e-3)" "unprognostic (6.26e-4)" "unprognostic (1.43e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-4)" "unprognostic (7.92e-2)" "unprognostic (2.67e-1)" "unprognostic (9.19e-3)" "unprognostic (4.43e-3)" 0.9 0.4 0.3 1.9 0.3 11.1 0.4 0.3 0.3 0.4 0.4 0.5 0.9 0.3 0.4 0.3 0.4 0.8 0.3 0.2 0.3 0.5 1.2 3.3 7.5 0.4 0.3 0.2 0.2 0.0 0.2 0.2 0.3 0.4 0.5 0.0 0.6 0.2 0.5 0.2 1.6 0.4 0.3 11.7 1.2 0.4 0.3 1.0 0.7 0.2 2.2 0.6 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 3.6 2.0 3.1 8.9 0.0 0.5 0.4 7.8 0.2 14.3 0.0 0.1 0.1 2.4 0.3 0.3 0.3 0.3 0.2 0.3 0.4 0.3 0.3 0.3 0.3 0.3 1.1 0.0 0.6 0.0 7.6 0.0 0.0 0.0 0.6 0.0 0.6 0.9 1.3 1.5 0.0 0.0 0.0 0.1 92.8 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 1.3 0.1 0.0 0.0 0.2 1.1 0.2 2.5 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 1.9 0.0 1.9 0.8 0.0 119.4 0.0 0.1 0.0 0.0 0.0 22.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.1 0.1 0.0 45.6 0.0 0.0 0.0 TBX22 "CLPA, CPX" ENSG00000122145 "T-box transcription factor 22" Q9Y458 X 80014753-80031774 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "testis: 11.1;thyroid gland: 4.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HDLM-2: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (6.58e-2)" "unprognostic (6.31e-2)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBX3 "TBX3-ISO, UMS, XHL" ENSG00000135111 "T-box transcription factor 3" O15119 12 114670255-114684175 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 178.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 613.9" "Cancer enhanced" "Detected in all" "prostate cancer: 49.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 103.0;BJ hTERT+: 97.3;RT4: 129.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005799, HPA075876" Supported Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA005799: AB_1857817, HPA075876: " "unprognostic (3.27e-1)" "unprognostic (2.64e-1)" "unprognostic (2.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.40e-2)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (2.99e-2)" "unprognostic (9.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (3.06e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "prognostic favorable (3.28e-4)" 13.3 178.4 5.1 2.5 4.7 0.0 34.1 3.9 5.7 37.5 2.9 7.4 37.6 32.8 44.6 2.8 24.0 4.5 13.2 3.8 14.9 12.9 31.3 32.8 1.4 4.6 4.4 44.2 2.9 1.0 12.9 41.3 4.8 80.4 3.7 1.8 18.9 53.2 10.4 14.9 30.3 10.0 3.8 7.0 6.0 1.3 6.6 1.3 50.0 16.5 1.7 53.9 34.2 3.7 2.4 18.2 0.0 0.0 26.1 35.6 40.1 103.0 97.3 39.0 38.3 16.3 4.4 0.0 1.6 18.0 2.4 4.7 8.4 3.6 47.7 0.0 12.3 0.0 4.8 48.1 8.4 0.0 0.0 16.0 2.4 13.1 26.8 0.0 0.5 0.0 3.8 0.0 3.4 1.6 0.0 0.5 0.2 53.0 5.4 0.0 0.0 2.6 0.0 129.3 6.6 19.4 14.6 6.6 3.6 44.6 5.1 0.2 0.0 11.9 7.7 6.8 33.9 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.7 3.9 5.7 3.8 14.9 4.6 4.4 4.8 3.8 6.6 3.7 48.9 0.0 1.9 0.3 1.8 9.8 85.2 5.8 7.4 14.3 110.3 80.5 12.5 0.0 1.1 35.0 4.2 60.7 0.7 12.0 0.0 0.6 1.5 3.3 144.7 38.6 4.9 0.0 0.0 0.0 7.0 41.3 5.1 3.8 0.0 3.9 1.1 40.2 6.1 1.7 0.0 23.9 4.1 0.9 4.6 2.8 5.3 2.9 3.6 14.0 0.0 1.9 0.0 0.0 0.0 0.3 22.4 6.0 0.0 72.4 37.9 0.1 0.4 2.0 39.5 27.2 58.2 0.1 3.8 3.2 9.8 613.9 2.0 112.0 12.1 69.1 TBX5 HOS ENSG00000089225 "T-box transcription factor 5" Q99593 12 114353911-114408442 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 88.1;lung: 20.8;placenta: 28.7" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 104.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 18.9;BJ hTERT+: 41.5;BJ hTERT+ SV40 Large T+: 9.2;BJ hTERT+ SV40 Large T+ RasG12V: 12.2;HAP1: 16.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008786, HPA064683" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA008786: AB_10601720, HPA064683: AB_2685320" "unprognostic (3.09e-2)" "unprognostic (1.53e-1)" "unprognostic (3.79e-2)" "unprognostic (2.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-7)" "unprognostic (2.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.34e-2)" "unprognostic (4.38e-3)" 3.4 0.0 0.1 0.0 0.0 0.0 4.4 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 88.1 0.9 0.0 0.0 0.0 20.8 0.6 0.3 0.1 0.0 0.0 1.3 0.0 28.7 0.3 3.4 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 5.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 18.9 41.5 9.2 12.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 16.3 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.9 0.0 0.3 0.1 0.3 0.0 0.0 0.2 2.9 0.0 0.6 1.6 0.0 0.1 0.0 0.0 0.0 4.5 0.1 0.1 104.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 7.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 TCEA3 TFIIS.H ENSG00000204219 "Transcription elongation factor A3" O75764 1 23380909-23424748 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 513.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 214.8;Hepatocytes: 205.9;Intestinal goblet cells: 376.2;Proximal tubular cells: 260.9;Undifferentiated cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 8.4;naive CD4 T-cell: 13.6" "Lineage enriched" "Detected in many" 5 "T-cells: 13.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 15.3;Hep G2: 55.1;OE19: 28.7;SiHa: 18.2;T-47d: 28.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044960, HPA055811" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA044960: AB_10964053, HPA055811: AB_2682932" "unprognostic (1.58e-1)" "unprognostic (1.75e-3)" "unprognostic (9.18e-2)" "unprognostic (3.82e-2)" "unprognostic (2.77e-3)" "prognostic favorable (2.56e-4)" "unprognostic (2.86e-2)" "unprognostic (4.70e-3)" "unprognostic (7.37e-3)" "unprognostic (2.85e-1)" "unprognostic (2.22e-2)" "unprognostic (3.27e-1)" "unprognostic (2.23e-1)" "unprognostic (4.01e-1)" "unprognostic (5.20e-2)" "unprognostic (3.15e-1)" "unprognostic (5.58e-2)" 17.5 95.6 4.7 4.6 4.3 0.6 19.6 4.1 4.7 35.7 7.8 87.1 15.8 17.0 7.3 40.5 28.3 11.6 71.6 4.0 4.4 64.9 160.7 20.4 2.4 6.0 4.9 81.9 229.4 16.3 14.9 3.9 5.4 59.9 39.8 3.2 100.3 14.5 513.3 53.4 35.2 9.2 5.2 10.6 75.9 4.7 4.1 1.8 41.2 173.1 4.5 36.2 38.7 5.1 0.0 0.1 0.5 0.5 2.5 15.3 9.0 6.4 4.1 3.2 1.9 4.1 0.5 0.2 0.7 7.9 1.0 9.1 0.5 0.1 2.8 0.0 0.1 0.0 6.9 55.1 1.9 0.8 0.0 10.1 2.8 2.9 0.0 7.1 0.4 0.1 0.0 0.0 1.1 1.5 0.4 6.1 0.0 28.7 1.8 0.1 0.0 0.2 0.0 0.1 0.5 0.1 18.2 0.8 0.8 1.5 28.4 2.8 0.4 0.0 0.2 0.7 0.0 0.5 5.3 0.0 0.5 0.5 0.6 0.0 0.2 0.0 0.4 0.7 0.4 0.0 8.4 1.1 2.9 0.0 13.6 6.1 0.0 0.2 0.2 0.9 0.8 2.3 4.7 4.3 4.1 4.7 4.0 4.4 6.0 4.9 5.4 5.2 4.1 5.1 10.5 125.0 109.5 4.2 1.9 27.4 53.4 30.9 30.7 2.3 46.3 42.4 109.8 100.1 57.2 42.3 2.1 3.3 1.9 158.0 199.6 37.7 6.1 7.7 6.6 13.4 55.9 5.7 2.8 97.9 33.9 45.2 69.3 20.8 9.5 214.8 8.2 205.9 1.5 25.2 4.5 376.2 6.1 7.6 65.4 17.9 17.1 8.4 24.9 3.7 3.2 6.8 3.1 2.0 1.3 25.5 143.0 15.4 0.5 38.8 154.3 260.9 29.4 1.4 19.7 90.1 24.0 0.7 2.6 61.1 54.8 2.2 8.4 52.0 223.5 73.9 TCEAL6 WEX2 ENSG00000204071 "Transcription elongation factor A like 6" Q6IPX3 X 102140476-102142970 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.4;pituitary gland: 73.4;testis: 26.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 40.4;Excitatory neurons: 9.1;Horizontal cells: 15.2;Inhibitory neurons: 10.4;Late spermatids: 6.7" "Cancer enriched" "Detected in single" 9 "glioma: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045564, HPA058982" Supported Uncertain Nucleoplasm NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA045564: AB_2679369, HPA058982: AB_2683870" "unprognostic (5.43e-2)" "unprognostic (6.54e-2)" "unprognostic (1.87e-3)" "unprognostic (6.69e-3)" "unprognostic (1.39e-1)" "unprognostic (2.69e-2)" "unprognostic (1.88e-2)" "unprognostic (3.89e-2)" "unprognostic (1.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.33e-2)" "unprognostic (1.18e-1)" 1.6 10.7 27.3 0.2 24.3 0.0 0.6 23.1 41.4 1.5 3.6 1.7 0.2 3.6 1.4 0.0 5.7 0.1 0.5 23.8 35.4 1.0 0.0 0.1 0.0 27.3 32.9 8.5 0.4 1.8 73.4 0.0 26.3 0.8 0.2 16.7 1.8 0.6 0.0 0.3 0.7 0.7 19.2 0.0 0.8 26.8 26.0 0.0 0.5 0.2 0.0 0.0 1.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 27.3 24.3 23.1 41.4 23.8 35.4 27.3 32.9 26.3 19.2 26.0 22.5 0.0 0.0 0.0 3.9 0.0 0.1 0.5 0.0 0.0 40.4 0.0 0.1 4.6 0.0 0.0 3.7 2.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.0 9.1 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.1 15.2 10.4 0.0 0.0 0.0 0.3 6.7 2.5 0.1 1.8 1.0 0.0 1.9 0.0 4.5 1.7 0.4 0.0 0.7 0.0 0.5 0.0 0.0 0.0 4.3 0.0 1.4 0.9 1.9 0.9 0.0 0.3 0.0 0.2 0.0 0.0 0.1 TCF19 SC1 ENSG00000137310 "Transcription factor 19" Q9Y242 6 31158547-31167159 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 37.0;Glandular and luminal cells: 17.6;Plasma cells: 21.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 82.8;GAMG: 47.0;HEK 293: 43.3;JURKAT: 40.9;Karpas-707: 39.2;SCLC-21H: 48.5;U-138 MG: 49.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA065994 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "HPA065994: " "unprognostic (1.41e-2)" "unprognostic (4.92e-2)" "unprognostic (4.00e-2)" "unprognostic (5.16e-3)" "unprognostic (1.99e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (5.66e-4)" "unprognostic (7.04e-2)" "unprognostic (1.35e-2)" "unprognostic (5.92e-2)" "unprognostic (1.74e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (3.54e-10)" "unprognostic (3.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.36e-2)" "unprognostic (1.21e-1)" 4.6 1.7 0.3 2.6 0.4 1.0 4.3 0.7 0.4 6.9 0.2 5.8 4.4 4.2 2.1 12.5 3.8 0.4 3.7 0.3 0.3 4.1 2.0 4.4 10.0 0.5 0.4 4.8 3.2 0.0 1.3 0.3 0.5 5.1 1.7 0.6 4.7 0.8 2.7 8.9 7.2 1.1 0.3 9.5 5.5 1.9 0.7 0.0 2.4 0.1 1.7 5.2 8.1 0.3 82.8 0.7 0.7 0.1 5.4 7.0 0.7 0.5 0.0 0.1 0.1 5.3 0.1 0.1 17.7 20.1 47.0 0.1 0.0 30.3 0.0 0.5 43.3 7.3 5.1 2.0 0.0 0.2 21.1 2.9 0.0 2.3 0.0 4.4 17.9 40.9 0.1 39.2 8.1 0.3 1.2 13.2 0.1 0.0 0.0 1.1 4.8 0.7 7.1 0.3 48.5 0.5 0.4 0.1 0.5 6.5 0.1 6.0 0.0 49.0 0.2 0.4 0.4 12.5 15.0 24.8 0.1 0.3 0.3 0.0 0.1 0.0 0.2 0.0 1.3 0.5 0.6 1.1 0.3 0.5 0.8 0.2 0.1 0.4 0.0 0.0 1.0 0.5 0.3 0.4 0.7 0.4 0.3 0.3 0.5 0.4 0.5 0.3 0.7 0.3 2.8 3.2 0.6 0.7 6.7 5.1 3.1 2.5 8.6 3.0 2.8 2.9 1.2 0.0 2.5 3.7 0.0 2.9 3.9 1.8 7.9 1.3 0.3 4.7 2.0 4.7 1.2 37.0 0.1 1.8 9.6 5.6 5.6 17.6 1.3 7.0 1.8 0.6 8.9 1.7 0.2 3.9 2.0 2.9 5.4 0.7 5.0 4.8 12.4 0.0 6.0 4.2 8.2 0.0 0.2 1.1 0.9 6.4 21.1 1.3 1.6 0.4 0.2 0.5 0.0 3.5 5.3 0.7 11.1 9.6 3.8 0.4 7.6 2.0 8.8 2.9 TCF20 "AR1, SPBP" ENSG00000100207 "Transcription factor 20" Q9UGU0 22 42160013-42343616 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 127.0;Inhibitory neurons: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017849, HPA036786" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "CAB017849: , HPA036786: AB_2675313" "unprognostic (2.17e-1)" "unprognostic (2.12e-2)" "prognostic favorable (1.88e-4)" "unprognostic (2.19e-2)" "unprognostic (1.19e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (4.89e-4)" "unprognostic (1.77e-1)" "unprognostic (2.36e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-3)" "unprognostic (7.30e-2)" "unprognostic (1.17e-3)" "unprognostic (3.07e-3)" "unprognostic (4.94e-1)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" 7.1 6.5 4.2 1.7 3.1 1.6 7.5 0.0 2.9 10.2 0.0 9.1 1.6 9.0 0.2 16.3 6.9 1.0 4.9 3.7 2.4 7.6 7.4 7.1 1.6 0.9 1.0 7.6 8.2 1.2 7.4 1.2 1.1 6.9 1.3 0.9 9.9 1.0 5.7 14.3 10.0 1.4 0.0 7.3 8.0 15.3 1.8 2.3 9.6 1.3 1.6 7.8 11.0 2.1 6.6 2.3 3.2 2.1 1.0 2.1 5.5 4.2 2.8 2.1 3.5 5.0 2.5 10.9 3.6 1.1 3.1 5.4 3.9 3.3 1.2 8.5 3.9 3.4 2.2 1.6 1.5 6.0 4.7 1.2 2.9 3.0 3.0 0.9 1.0 3.1 4.1 3.9 1.6 3.0 9.4 1.8 3.4 2.2 3.1 4.7 2.0 5.7 0.5 5.2 6.2 2.0 2.7 2.0 2.7 2.0 1.2 4.8 3.9 3.8 8.9 3.9 1.9 7.0 6.2 4.5 2.3 4.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.1 0.0 2.9 3.7 2.4 0.9 1.0 1.1 0.0 1.8 2.1 10.0 0.0 9.6 23.5 9.1 22.6 11.3 19.4 12.0 25.1 11.5 6.9 7.3 17.2 10.1 9.2 18.8 6.3 11.0 16.6 0.0 10.8 127.0 14.2 9.9 9.3 16.8 9.9 54.0 7.5 5.5 8.1 10.7 22.2 1.3 10.0 8.9 12.6 6.2 10.1 63.5 13.8 12.2 12.4 13.3 36.2 12.5 9.4 7.2 22.5 12.0 5.6 6.2 29.7 55.0 13.3 13.5 6.4 8.7 20.9 13.0 6.0 13.4 12.6 6.6 5.8 8.5 19.1 13.4 19.5 22.9 4.5 13.0 4.3 17.9 14.6 TCHH THH ENSG00000159450 Trichohyalin Q07283 1 152106317-152115454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 41.4" "Cell type enhanced" "Detected in some" "Kupffer cells: 26.2;Langerhans cells: 9.5;Macrophages: 21.8;Spermatocytes: 22.6;Spermatogonia: 29.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.6;SCLC-21H: 1.1;THP-1: 2.0" "Low region specificity" "Detected in many" HPA028375 Approved NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "HPA028375: AB_10601722" "unprognostic (7.70e-3)" "unprognostic (3.84e-2)" "unprognostic (1.14e-3)" "unprognostic (1.14e-1)" "unprognostic (2.07e-1)" "unprognostic (2.30e-2)" "unprognostic (4.97e-3)" "unprognostic (2.15e-2)" "unprognostic (1.84e-2)" "unprognostic (7.12e-5)" "unprognostic (2.03e-1)" "unprognostic (6.55e-2)" "unprognostic (5.90e-6)" "unprognostic (5.58e-2)" "unprognostic (1.12e-1)" "unprognostic (9.71e-2)" "unprognostic (9.28e-7)" 0.7 0.1 0.1 0.1 0.1 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.3 0.2 0.0 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 41.4 0.2 0.0 0.0 2.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.2 0.0 0.7 0.0 0.0 3.6 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.1 1.0 0.1 0.1 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.3 0.0 0.0 0.3 2.0 0.0 0.0 0.9 0.2 0.1 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.5 6.4 0.1 0.5 2.8 0.5 1.2 2.5 2.0 0.0 0.3 1.8 0.0 0.6 0.0 0.3 0.0 0.0 0.2 1.4 0.2 3.5 1.8 0.0 0.5 0.2 7.5 0.9 0.0 0.8 0.0 0.1 2.5 0.0 0.6 0.0 0.5 0.5 0.0 26.2 9.5 0.2 0.3 21.8 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 1.3 0.0 0.0 0.7 0.0 0.0 3.2 1.4 22.6 29.1 1.0 2.4 5.2 0.8 0.1 0.0 0.1 TCHP "MGC10854, TpMs" ENSG00000139437 "Trichoplein keratin filament binding" Q9BT92 12 109900264-109983841 "Predicted intracellular proteins" "Apoptosis, Cilium biogenesis/degradation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038638, HPA061543" Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Centrosome, Cytosol" "HPA038638: AB_10670785, HPA061543: AB_2684556" "unprognostic (2.21e-1)" "unprognostic (1.51e-2)" "unprognostic (2.58e-1)" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (4.82e-2)" "unprognostic (1.42e-2)" "unprognostic (7.94e-2)" "unprognostic (1.59e-2)" "unprognostic (9.75e-2)" "unprognostic (1.15e-3)" "unprognostic (4.63e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.52e-4)" "unprognostic (1.35e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" 6.5 7.3 9.7 8.9 10.6 6.8 6.6 10.9 11.3 10.1 8.1 10.4 7.3 9.1 7.5 15.4 7.6 5.9 8.1 9.4 10.5 7.8 5.6 7.3 11.7 10.4 10.5 8.9 10.9 7.4 6.4 7.6 10.5 8.6 6.8 9.2 10.5 7.9 9.1 27.4 8.2 7.6 9.2 11.8 8.2 9.3 10.7 10.4 8.6 7.0 11.6 9.3 13.8 11.0 27.6 24.0 12.7 15.3 11.0 11.9 17.3 25.6 13.4 21.8 12.1 15.2 9.4 38.2 7.2 14.9 11.8 22.5 14.0 16.0 19.5 20.7 13.8 27.6 15.3 15.0 13.3 38.0 20.4 9.8 19.1 22.9 17.1 13.7 19.7 23.8 30.5 7.5 18.2 18.9 35.0 38.4 15.3 6.6 24.2 31.7 24.9 32.4 9.9 24.2 18.8 19.8 18.5 19.8 18.2 9.0 17.9 27.2 21.8 22.2 15.5 14.3 32.7 21.8 29.5 27.0 23.5 31.0 23.7 0.0 2.7 2.3 3.6 1.7 2.6 2.0 3.2 4.5 2.1 1.3 3.2 2.5 2.7 5.9 3.7 1.5 4.7 3.1 9.7 10.6 10.9 11.3 9.4 10.5 10.4 10.5 10.5 9.2 10.7 11.0 11.7 19.2 21.4 18.9 10.4 9.8 7.7 9.5 8.0 28.9 11.3 11.4 13.2 17.2 12.0 7.3 18.8 11.2 14.3 12.8 9.8 20.7 32.5 23.0 19.1 15.2 14.8 15.4 8.3 15.1 8.4 11.4 10.2 13.2 13.3 15.7 7.9 7.4 11.6 25.2 12.3 10.7 10.2 13.0 7.8 47.6 11.1 11.4 7.2 1.9 14.3 13.9 35.0 10.1 19.4 18.8 14.4 27.8 15.0 9.1 14.2 6.6 33.6 24.0 13.1 19.6 12.6 25.1 33.2 14.8 24.7 7.0 15.9 30.9 12.2 30.7 TCIRG1 "a3, Atp6i, ATP6N1C, ATP6V0A3, OC-116, OC116, TIRC7" ENSG00000110719 "T cell immune regulator 1, ATPase H+ transporting V0 subunit a3" Q13488 11 68039025-68050895 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 289.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 135.5;Kupffer cells: 115.2;Macrophages: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 131.9;RPMI-8226: 138.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038742 Approved Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria "HPA038742: AB_10795138" "unprognostic (5.35e-2)" "unprognostic (5.01e-2)" "unprognostic (1.81e-2)" "unprognostic (1.50e-2)" "unprognostic (6.98e-3)" "unprognostic (1.25e-1)" "unprognostic (5.07e-2)" "unprognostic (6.43e-2)" "unprognostic (7.03e-2)" "unprognostic (2.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.50e-11)" "unprognostic (2.48e-3)" "unprognostic (7.88e-3)" "unprognostic (2.50e-1)" "prognostic favorable (9.45e-6)" 56.8 112.5 7.1 46.1 7.1 97.7 47.2 9.2 14.5 85.1 11.4 66.6 44.2 58.0 18.6 45.3 61.4 11.7 27.9 6.6 7.2 35.5 61.7 113.9 30.9 10.9 9.3 49.1 289.2 4.4 20.3 14.1 12.0 72.2 8.0 0.3 57.9 16.1 10.5 25.9 87.0 12.1 9.1 194.8 59.2 6.7 18.1 12.1 52.5 3.9 13.4 56.1 60.7 10.8 31.8 57.2 0.8 0.2 25.1 19.7 39.0 61.5 29.4 17.2 16.3 1.3 92.0 2.7 32.9 21.9 26.2 39.0 3.7 23.5 3.6 82.1 1.9 22.0 80.6 18.9 23.4 16.3 131.9 22.8 13.5 21.2 1.4 0.0 11.8 1.2 11.6 8.4 5.7 10.7 0.8 97.8 3.5 44.6 14.4 26.8 0.9 138.6 16.2 17.6 3.0 0.7 26.0 33.4 16.8 6.1 36.3 41.1 42.3 33.2 25.9 93.3 11.4 1.3 1.2 4.8 74.0 26.7 16.2 21.7 65.5 72.8 15.7 109.0 12.7 11.3 11.7 16.9 49.0 7.5 6.6 7.2 150.0 32.1 144.3 33.8 12.1 47.8 7.1 7.1 9.2 14.5 6.6 7.2 10.9 9.3 12.0 9.1 18.1 10.8 40.6 28.9 59.8 0.3 37.1 6.2 13.2 36.2 7.4 0.7 14.9 8.9 1.6 18.6 57.1 7.3 0.0 21.7 60.6 74.2 0.0 30.4 0.4 13.3 16.7 22.1 23.9 15.2 0.3 67.0 54.1 24.9 135.5 21.5 50.0 29.5 21.0 17.8 105.1 0.0 0.6 32.4 18.3 115.2 22.8 0.6 5.9 132.3 5.4 8.4 74.9 0.7 45.3 0.5 0.1 51.8 85.4 13.2 59.1 10.6 45.5 2.0 47.9 1.0 39.5 7.7 26.0 0.1 2.9 10.4 5.3 26.5 46.5 9.0 36.2 19.0 TCN2 "D22S676, D22S750, TC2" ENSG00000185339 "Transcobalamin 2" P20062 22 30607003-30627271 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Hepatic stellate cells: 137.4;Kupffer cells: 144.1;Proximal enterocytes: 563.6;Proximal tubular cells: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 43.8;intermediate monocyte: 66.5;non-classical monocyte: 24.4" "Lineage enriched" "Detected in many" 8 "monocytes: 66.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 117.6;HUVEC TERT2: 142.6;Karpas-707: 184.0;RPTEC TERT1: 70.7;TIME: 85.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000837 Approved Cytosol "Secreted to blood" NA NA 19000000 "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA000837: AB_1080235" "unprognostic (6.43e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.53e-3)" "unprognostic (3.17e-1)" "unprognostic (1.49e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.64e-4)" "unprognostic (1.52e-2)" "unprognostic (2.90e-1)" "unprognostic (1.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.59e-1)" "unprognostic (6.95e-3)" "unprognostic (4.94e-3)" "unprognostic (2.09e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" 49.6 30.6 24.6 16.0 24.1 5.5 37.9 25.5 30.6 25.9 27.1 23.4 23.6 28.7 20.3 8.6 21.5 50.1 28.7 22.7 25.3 115.8 17.3 37.7 35.3 27.1 26.1 14.8 12.1 8.6 15.1 18.6 27.7 16.0 27.8 11.1 13.2 45.4 6.0 9.0 59.5 36.8 25.5 46.7 17.4 21.9 29.7 6.4 26.4 13.7 10.0 22.0 14.7 25.3 0.2 9.5 41.8 0.2 24.6 117.6 1.4 3.1 30.9 8.0 13.1 4.6 21.2 0.6 45.7 6.2 0.7 1.5 3.7 2.2 2.5 0.0 2.3 0.2 1.2 2.0 58.5 0.6 33.7 19.8 2.5 6.1 5.1 8.8 142.6 0.0 0.8 184.0 12.7 0.1 0.1 3.3 16.4 11.7 1.0 4.9 6.0 64.2 70.7 1.1 14.4 1.9 0.3 0.6 12.0 2.8 0.4 2.0 85.3 26.4 3.5 3.3 1.3 5.1 1.4 0.2 9.5 1.7 0.6 0.0 43.8 0.0 0.1 66.5 0.7 0.0 0.8 0.4 7.9 0.0 0.3 0.6 1.4 0.0 24.4 1.5 0.2 18.8 24.6 24.1 25.5 30.6 22.7 25.3 27.1 26.1 27.7 25.5 29.7 25.3 105.0 3.2 3.9 3.9 3.7 5.2 2.2 4.7 0.6 8.0 7.1 5.1 6.5 27.1 13.7 12.9 20.9 0.4 0.5 70.9 7.9 7.8 1.1 3.5 5.4 64.6 6.7 0.8 0.2 6.0 0.8 19.5 5.1 6.2 4.5 23.4 137.4 5.6 45.9 1.7 1.9 28.6 4.1 144.1 9.4 1.4 10.5 53.8 23.2 8.4 8.8 7.4 0.0 5.5 1.7 5.1 50.2 9.8 13.5 2.0 563.6 125.8 2.8 29.1 13.1 0.9 5.5 1.0 12.6 0.5 5.3 0.4 2.2 5.6 21.0 2.7 TDRD10 DKFZp434M202 ENSG00000163239 "Tudor domain containing 10" Q5VZ19 1 154502219-154548147 "Cancer-related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 55.6" "Group enriched" "Detected in some" 5 "Early spermatids: 61.8;Late spermatids: 89.0;Spermatocytes: 103.7" "Cancer enhanced" "Detected in many" "testis cancer: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.0;TIME: 1.4" "Not detected" "Not detected" HPA054327 Approved Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA054327: AB_2682452" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.33e-3)" "unprognostic (9.69e-3)" "unprognostic (5.80e-3)" "unprognostic (2.99e-1)" "unprognostic (5.97e-3)" "unprognostic (2.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.00e-3)" "unprognostic (1.61e-1)" "unprognostic (1.34e-3)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "prognostic favorable (8.04e-5)" "unprognostic (1.62e-1)" 11.1 4.5 3.7 0.5 3.7 0.1 6.8 3.1 3.7 5.1 3.3 2.8 0.7 4.2 2.3 2.4 6.5 1.6 7.6 3.3 3.2 3.5 4.5 8.1 0.8 3.2 3.5 10.1 0.9 0.9 2.6 1.7 3.3 3.9 1.3 0.1 1.8 1.2 1.9 2.3 3.5 1.8 3.2 8.9 1.9 55.6 3.7 0.5 11.0 1.4 0.4 3.9 3.6 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.7 3.1 3.7 3.3 3.2 3.2 3.5 3.3 3.2 3.7 3.1 10.0 3.2 6.7 4.9 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.5 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.8 0.0 0.1 8.2 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 1.3 0.7 6.1 0.4 0.4 0.0 0.5 0.0 0.0 4.0 2.1 89.0 2.5 1.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 103.7 16.5 0.1 0.3 0.0 0.0 0.1 0.0 0.0 TEAD2 "ETF, TEF-4, TEF4" ENSG00000074219 "TEA domain transcription factor 2" Q15562 19 49340595-49362457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 51.1;Early spermatids: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 1.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 27 "B-cells: 2.7" "Cell line enhanced" "Detected in many" "AF22: 135.3;AN3-CA: 147.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066292, HPA069963" Supported Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA066292: AB_2685651, HPA069963: AB_2686222" "unprognostic (2.69e-2)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (1.03e-2)" "unprognostic (8.58e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (8.66e-4)" "unprognostic (2.91e-1)" "unprognostic (4.47e-3)" "unprognostic (1.11e-1)" "unprognostic (3.96e-3)" "unprognostic (1.24e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-1)" "unprognostic (6.78e-2)" 32.8 17.8 7.5 15.4 7.1 0.2 31.6 6.6 7.9 41.8 16.2 50.4 7.6 39.6 12.4 11.0 34.2 15.5 55.5 7.5 6.8 34.5 11.9 35.7 9.0 8.7 8.3 33.5 26.8 19.4 9.2 17.7 7.7 26.5 11.2 3.4 18.5 22.7 12.9 10.7 18.5 38.4 7.6 14.8 31.3 26.6 8.3 3.1 16.9 22.1 7.3 27.2 24.4 6.6 12.5 28.6 135.3 147.6 14.2 20.8 24.3 22.8 23.9 25.6 29.7 2.3 6.8 1.2 29.6 38.5 13.1 13.9 37.5 7.7 14.1 0.1 17.5 0.0 27.2 19.3 24.6 0.1 0.3 24.8 17.8 17.4 8.4 50.6 92.1 0.1 22.0 0.0 36.1 15.3 0.0 0.2 45.4 35.2 36.2 0.0 40.8 0.2 23.3 0.2 0.2 82.0 38.1 5.6 10.1 46.1 40.5 3.5 55.0 45.9 28.1 9.9 1.8 0.1 0.1 4.8 1.7 0.6 18.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 7.1 6.6 7.9 7.5 6.8 8.7 8.3 7.7 7.6 8.3 6.6 26.1 3.2 3.2 0.0 3.8 3.3 6.9 5.9 8.6 0.4 21.1 9.5 1.0 8.6 3.4 12.9 0.0 0.6 0.4 1.3 1.9 51.1 76.6 7.3 20.7 29.5 7.1 3.2 0.1 26.2 23.7 15.0 9.7 6.5 0.0 14.7 21.4 2.8 0.6 0.0 0.1 6.6 8.2 0.9 3.6 29.6 15.2 0.7 5.4 1.9 0.0 15.9 0.0 0.0 0.1 22.7 4.9 22.2 0.1 7.2 0.1 0.2 1.2 0.4 32.9 7.6 28.7 2.1 2.4 2.0 1.6 1.2 0.5 4.4 6.8 2.8 TEAD4 "EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1" ENSG00000197905 "TEA domain transcription factor 4" Q15561 12 2959330-3040676 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 127.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 50.3;Exocrine glandular cells: 38.3;Hepatic stellate cells: 32.2;Proximal enterocytes: 37.9;Syncytiotrophoblasts: 34.6" "Cancer enriched" "Detected in all" 5 "testis cancer: 78.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 364.1" "Region enriched" "Detected in single" 5 "cerebellum: 3.1" "Low region specificity" "Detected in all" HPA056896 Uncertain Supported Nucleoplasm NA NA "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA056896: AB_2683268" "unprognostic (3.68e-1)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.55e-3)" "unprognostic (1.33e-1)" "unprognostic (3.68e-1)" "unprognostic (9.20e-3)" "unprognostic (2.21e-3)" "unprognostic (3.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (9.78e-9)" "unprognostic (5.05e-3)" "unprognostic (8.43e-2)" "unprognostic (2.42e-2)" "unprognostic (1.23e-3)" 17.4 5.2 4.2 7.1 3.6 0.4 12.0 5.6 5.5 10.4 4.0 8.1 4.8 9.7 1.0 7.8 8.3 4.5 20.0 3.5 3.9 33.7 4.6 26.0 1.6 5.3 4.8 4.5 51.1 1.6 3.4 10.9 6.1 8.5 4.1 0.5 8.0 5.0 127.3 16.4 8.4 8.9 4.0 9.0 8.1 3.7 6.4 1.6 23.6 46.7 2.4 11.3 7.1 3.6 37.6 51.5 13.0 36.2 4.0 8.7 137.8 29.5 15.6 49.7 27.8 99.6 39.0 0.3 22.2 22.5 34.0 52.5 51.2 364.1 46.1 0.2 41.2 59.1 43.7 87.7 18.8 12.8 10.7 12.2 14.8 43.3 66.7 20.8 42.9 23.4 38.4 0.5 17.5 53.2 0.7 0.3 99.5 48.0 30.0 27.4 73.7 28.9 23.6 15.3 7.4 13.2 36.4 89.9 27.1 93.8 61.2 21.8 49.4 28.7 100.1 20.2 15.7 0.1 0.2 0.4 23.3 0.0 37.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.6 5.6 5.5 3.5 3.9 5.3 4.8 6.1 4.0 6.4 3.6 17.1 12.8 4.7 0.0 0.1 12.2 12.6 6.1 9.1 0.1 6.6 3.7 2.4 5.7 2.3 7.3 0.0 50.3 0.4 3.7 5.9 17.7 0.3 3.0 5.1 25.9 0.0 0.0 1.6 38.3 18.3 6.6 4.1 5.0 5.7 3.4 32.2 0.4 5.2 0.0 0.5 3.7 2.0 0.8 1.5 2.3 0.0 0.5 8.8 3.7 0.0 0.0 0.0 0.0 0.4 21.1 0.9 0.4 1.2 28.9 37.9 21.1 1.5 0.1 0.0 9.3 12.2 0.5 6.4 5.4 7.7 34.6 0.5 0.4 7.1 4.9 TECR "GPSN2, MRT14, SC2, TER" ENSG00000099797 "Trans-2,3-enoyl-CoA reductase" Q9NZ01 19 14517085-14565980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1013.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029780, HPA056488" Supported Supported "Endoplasmic reticulum" NA NA 10000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA029780: AB_10603348, HPA056488: AB_2683149" "unprognostic (9.73e-2)" "unprognostic (3.69e-3)" "unprognostic (1.55e-1)" "unprognostic (8.08e-3)" "unprognostic (1.20e-1)" "unprognostic (3.96e-2)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.36e-1)" "unprognostic (9.16e-2)" "unprognostic (1.29e-1)" "unprognostic (5.05e-2)" "unprognostic (3.65e-3)" "unprognostic (2.53e-3)" "unprognostic (2.34e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.60e-4)" 102.7 162.6 189.0 43.1 201.7 74.2 100.4 220.8 237.5 156.8 216.5 78.5 106.1 53.2 103.2 373.2 87.1 49.7 78.4 180.1 200.0 112.2 133.9 67.8 55.7 209.6 191.2 80.9 105.5 306.1 78.7 68.0 212.2 85.7 59.3 82.8 222.3 83.5 366.3 263.5 95.9 36.7 207.6 75.4 81.7 182.7 199.9 65.8 92.7 209.6 85.3 51.6 185.9 230.2 220.5 162.1 149.5 169.6 214.7 97.2 156.9 62.8 175.2 196.3 242.9 225.3 246.2 113.8 127.4 134.2 152.4 328.8 158.1 254.3 84.0 192.3 165.9 193.7 225.4 254.6 129.7 139.5 143.7 144.9 201.8 174.3 96.1 98.4 93.7 169.2 128.9 391.5 104.0 289.3 170.1 248.3 155.6 556.1 227.6 154.4 96.1 521.1 275.1 115.8 183.2 113.0 103.1 278.4 139.6 77.2 151.3 274.4 55.2 160.5 66.8 141.0 212.6 118.4 119.8 122.7 163.8 212.6 162.2 55.6 72.7 52.5 137.8 106.4 148.8 100.1 180.1 159.1 124.2 99.1 207.1 164.5 32.7 183.7 83.9 137.1 290.1 170.9 189.0 201.7 220.8 237.5 180.1 200.0 209.6 191.2 212.2 207.6 199.9 230.2 60.4 73.7 71.1 47.7 87.6 169.5 227.5 297.9 125.7 90.8 161.1 155.6 52.9 120.1 221.5 165.5 123.0 509.5 88.1 159.2 56.7 166.2 443.9 102.2 40.1 64.7 100.0 80.1 15.3 225.1 525.5 81.8 89.7 64.2 36.1 90.1 73.2 143.1 188.0 112.7 19.2 144.0 199.4 113.8 99.3 1013.1 72.7 77.8 163.7 18.7 61.6 577.9 103.0 12.5 46.5 104.8 128.2 60.2 206.1 110.2 343.2 202.9 213.1 177.5 65.7 68.4 286.7 215.0 134.2 255.3 239.7 486.2 117.7 116.0 216.2 196.5 TENM2 "KIAA1127, ODZ2, Ten-M2, TEN2" ENSG00000145934 "Teneurin transmembrane protein 2" Q9NT68 5 167284799-168264157 "Predicted membrane proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 9.8;heart muscle: 35.1" "Group enriched" "Detected in many" 5 "Astrocytes: 512.9;Excitatory neurons: 706.2;Inhibitory neurons: 965.9" "Cancer enriched" "Detected in many" 6 "head and neck cancer: 15.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 66.1;HBEC3-KT: 43.0;HDLM-2: 43.3;U-138 MG: 74.6;U-2 OS: 64.0;U-251 MG: 50.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038018, HPA038420, HPA068691" Uncertain Approved Nucleoli No No 11000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "HPA038018: , HPA038420: AB_10674682, HPA068691: AB_2686019" "unprognostic (6.00e-2)" "unprognostic (1.50e-1)" "unprognostic (2.94e-2)" "unprognostic (9.16e-3)" "unprognostic (3.88e-3)" "unprognostic (3.81e-3)" "unprognostic (5.81e-2)" "unprognostic (2.41e-1)" "unprognostic (4.62e-2)" "unprognostic (2.10e-2)" "unprognostic (3.68e-3)" "unprognostic (4.34e-2)" "unprognostic (4.69e-5)" "unprognostic (3.47e-2)" "unprognostic (1.03e-1)" "unprognostic (5.16e-4)" "prognostic unfavorable (7.52e-4)" 0.1 0.5 2.9 0.0 4.7 0.0 1.9 0.0 9.8 1.3 0.0 0.2 0.4 0.0 0.5 1.9 0.1 0.4 35.1 6.0 1.2 0.8 1.3 0.2 0.0 0.6 0.1 0.7 0.1 0.0 0.7 0.0 1.6 2.2 0.1 4.1 0.5 1.0 0.0 3.2 0.2 0.0 0.0 0.0 0.1 1.3 4.3 2.2 0.4 0.5 1.0 0.1 2.0 0.0 0.1 0.0 13.4 0.0 0.0 0.4 0.0 1.9 0.0 0.7 1.8 0.0 0.0 0.0 0.0 66.1 1.7 0.0 0.0 43.0 0.8 43.3 0.0 0.0 0.2 0.0 2.0 0.0 0.0 3.0 7.4 0.3 5.3 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.3 9.8 0.2 0.0 0.0 6.6 0.0 0.1 0.0 0.1 2.4 3.8 0.1 0.0 74.6 64.0 0.1 50.0 0.0 0.0 0.0 7.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 4.7 0.0 9.8 6.0 1.2 0.6 0.1 1.6 0.0 4.3 0.0 0.5 0.0 0.0 512.9 0.0 14.8 1.1 20.3 33.6 15.5 0.3 13.0 144.0 0.0 1.4 0.0 18.8 0.0 0.0 1.0 0.0 3.4 23.5 0.1 0.3 1.7 0.0 0.0 706.2 0.2 0.0 2.2 0.0 0.2 1.3 1.6 0.4 5.1 0.1 121.1 965.9 0.7 0.0 0.0 1.2 18.2 4.4 0.2 1.8 36.5 0.0 2.3 0.0 21.6 12.8 0.0 0.0 61.7 0.0 1.4 0.3 0.0 0.6 1.8 0.0 0.4 1.5 1.2 1.1 1.4 1.7 0.0 0.1 0.0 0.4 0.1 TERB2 "C15orf43, MGC33951" ENSG00000167014 "Telomere repeat binding bouquet formation protein 2" Q8NHR7 15 44956687-44979229 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 22.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041780 Uncertain Nucleoplasm,Nucleoli No NA "Cluster 83: Testis - Spermatogenesis" Nucleoli Nucleoplasm "HPA041780: AB_10796460" "unprognostic (1.42e-3)" "unprognostic (4.19e-2)" "unprognostic (1.29e-1)" "unprognostic (3.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TESC "CHP3, FLJ20607, TSC" ENSG00000088992 Tescalcin Q96BS2 12 117038923-117099479 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 329.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 183.0;Erythroid cells: 222.9;Exocrine glandular cells: 481.2;Gastric mucus-secreting cells: 316.0;Late spermatids: 319.3;Pancreatic endocrine cells: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 261.1" "Lineage enriched" "Detected in all" 5 "monocytes: 261.1" "Cell line enhanced" "Detected in many" "HMC-1: 398.5;NB-4: 675.1;OE19: 288.1;U-937: 221.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053200 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm Cytosol "HPA053200: AB_2682079" "unprognostic (4.53e-3)" "unprognostic (5.98e-2)" "unprognostic (6.50e-2)" "unprognostic (2.23e-3)" "unprognostic (6.31e-2)" "unprognostic (2.05e-3)" "unprognostic (4.98e-3)" "unprognostic (3.35e-1)" "unprognostic (4.35e-1)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.69e-2)" "unprognostic (8.65e-2)" "unprognostic (2.57e-1)" "unprognostic (1.56e-2)" "unprognostic (5.67e-3)" 8.1 46.5 17.4 10.3 36.8 118.8 8.9 16.4 25.4 4.3 15.7 3.8 7.2 3.9 121.9 3.3 4.0 36.1 71.5 26.5 15.0 26.5 4.9 10.2 8.0 17.8 15.0 5.3 102.4 9.4 26.7 10.2 18.2 9.8 2.8 0.5 329.9 19.7 5.1 9.7 7.3 2.8 14.8 11.9 138.4 31.1 15.5 7.4 10.7 8.1 10.3 29.3 5.3 18.9 0.2 97.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 4.3 13.8 4.7 0.0 0.2 0.6 8.1 0.0 0.0 37.5 19.2 115.5 9.8 78.1 0.0 49.2 398.5 0.1 0.0 0.0 0.0 0.0 0.0 18.5 54.0 0.9 0.0 2.2 95.5 675.1 9.0 288.1 0.0 0.4 0.0 52.4 56.5 15.0 17.0 6.1 0.1 0.1 3.6 0.9 0.0 53.9 0.0 0.0 1.7 0.2 0.4 17.0 38.2 0.0 0.1 221.8 0.5 0.0 51.0 51.5 7.0 67.9 0.4 5.5 2.4 9.1 35.8 13.1 0.3 3.8 12.6 11.6 261.1 2.6 3.5 19.0 17.4 36.8 16.4 25.4 26.5 15.0 17.8 15.0 18.2 14.8 15.5 18.9 35.6 0.0 0.0 5.9 16.2 2.7 0.3 0.4 1.8 0.8 5.5 67.1 58.3 183.0 0.9 12.9 0.0 0.4 21.1 0.2 74.3 159.5 106.5 1.3 0.7 43.6 1.8 222.9 26.1 481.2 0.6 7.9 316.0 3.2 71.1 1.2 1.8 0.5 48.0 0.0 2.0 1.5 0.0 17.9 6.1 319.3 3.1 30.6 72.9 8.4 41.0 0.2 25.7 2.5 1.5 215.6 0.9 3.4 25.8 3.5 0.2 6.1 0.0 1.5 144.7 1.9 68.4 63.0 20.3 0.5 2.0 1.2 28.3 66.7 2.3 1.3 TESK2 ENSG00000070759 "Testis associated actin remodelling kinase 2" Q96S53 1 45343883-45491163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 222.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 14.6;RT4: 14.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027257, HPA063869" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA027257: AB_10602477, HPA063869: AB_2685137" "unprognostic (2.95e-1)" "prognostic favorable (2.22e-4)" "unprognostic (3.90e-2)" "unprognostic (5.04e-3)" "unprognostic (6.03e-2)" "unprognostic (1.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.43e-2)" "unprognostic (5.15e-2)" "unprognostic (2.96e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (4.36e-2)" "unprognostic (2.49e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-2)" "unprognostic (2.01e-1)" 3.8 2.1 7.1 2.8 10.6 10.2 6.6 10.3 8.3 6.4 4.8 5.3 8.6 3.2 3.7 7.1 3.0 2.6 2.4 7.3 8.0 2.5 6.9 3.9 3.9 10.8 10.1 9.8 3.6 3.4 2.4 3.5 10.3 15.5 7.0 2.8 8.4 2.6 8.3 12.7 10.8 2.9 8.5 5.3 4.5 9.6 9.9 4.2 3.4 4.7 5.2 4.7 7.4 15.1 1.9 0.0 0.9 0.1 3.5 1.8 14.6 0.7 4.9 2.1 3.6 4.3 1.7 6.2 0.6 1.8 5.4 2.3 3.9 3.1 1.6 4.4 4.9 4.2 2.0 3.2 1.9 1.4 11.1 1.9 3.2 2.4 3.4 3.2 1.7 8.1 0.8 12.4 1.4 0.7 3.6 2.9 3.8 1.8 1.8 5.2 0.1 1.5 1.9 14.7 0.4 1.6 3.8 7.3 14.1 8.6 11.3 1.8 0.0 0.2 2.1 1.3 1.3 8.0 5.0 1.2 1.1 0.0 1.0 12.8 4.6 13.3 2.7 3.4 1.9 8.0 2.5 1.8 2.4 6.6 4.1 2.3 19.0 1.5 8.0 1.3 1.9 3.4 7.1 10.6 10.3 8.3 7.3 8.0 10.8 10.1 10.3 8.5 9.9 15.1 3.9 0.0 2.8 54.2 10.7 7.8 7.1 2.8 14.2 2.4 11.9 9.4 1.3 4.3 3.4 0.0 14.6 8.3 4.2 13.9 0.0 1.3 23.7 4.6 1.8 3.2 4.2 5.0 10.2 2.7 2.8 3.7 7.7 8.9 7.0 2.4 2.2 6.3 6.8 0.0 6.7 6.9 4.1 5.5 4.4 7.8 2.8 6.0 3.6 15.9 4.6 1.1 4.1 18.6 222.9 1.1 7.3 1.9 9.8 10.6 14.9 1.2 2.0 3.1 6.6 2.6 6.1 22.0 13.6 12.6 8.5 14.8 4.7 1.8 4.9 8.0 TEX264 "FLJ13935, ZSIG11" ENSG00000164081 "Testis expressed 264, ER-phagy receptor" Q9Y6I9 3 51662693-51704323 "Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 374.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005002, HPA017739" Enhanced Approved Nucleoli,Cytosol "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli, Cytosol" "CAB005002: AB_425976, HPA017739: AB_1857910" "unprognostic (2.80e-3)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (2.79e-3)" "unprognostic (8.11e-2)" "unprognostic (8.26e-3)" "unprognostic (2.05e-1)" "unprognostic (3.06e-3)" "unprognostic (2.30e-1)" "unprognostic (5.19e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.83e-1)" "prognostic favorable (7.95e-9)" "unprognostic (4.99e-2)" "unprognostic (3.65e-1)" "unprognostic (3.17e-1)" "unprognostic (4.67e-2)" 34.7 73.4 43.5 23.1 46.5 22.3 35.6 48.7 51.7 39.0 53.1 41.5 39.0 34.2 41.2 41.1 44.0 39.7 41.4 43.8 47.2 67.6 65.3 29.8 33.5 47.2 45.5 31.3 54.3 88.5 26.2 29.4 46.4 45.1 34.5 20.4 58.7 46.9 34.2 69.3 37.6 26.3 46.3 40.9 46.7 111.5 45.9 29.1 48.7 29.6 26.3 35.9 34.9 48.4 36.5 65.5 11.6 59.3 116.8 56.4 23.5 31.0 72.0 50.1 50.1 35.2 84.2 51.6 21.9 44.1 84.2 34.7 32.7 61.6 23.7 42.0 51.9 49.6 40.2 47.8 104.0 31.5 53.6 74.8 96.9 56.3 57.1 45.3 36.9 39.0 26.6 87.7 51.9 42.1 50.9 73.3 12.6 59.8 72.7 24.3 15.3 98.7 79.7 50.1 16.5 26.8 37.4 101.5 48.0 15.7 49.6 66.0 27.3 49.8 20.8 53.0 41.2 61.0 71.3 26.4 61.5 65.9 50.9 99.2 110.1 69.3 119.7 115.6 120.3 98.6 122.6 113.6 104.6 102.4 100.9 103.1 23.5 76.1 115.6 92.4 159.9 139.9 43.5 46.5 48.7 51.7 43.8 47.2 47.2 45.5 46.4 46.3 45.9 48.4 63.6 35.3 21.9 12.4 36.7 34.8 46.7 123.9 45.5 33.5 69.9 68.2 24.4 65.8 68.2 99.3 58.4 142.9 52.3 70.3 62.6 83.1 57.7 44.9 31.8 54.8 32.9 24.8 6.5 75.7 88.9 41.4 29.0 48.2 16.5 45.3 38.9 63.1 105.4 42.1 9.1 56.5 118.0 48.3 45.5 61.2 51.0 47.8 65.8 8.4 56.1 62.6 89.6 7.5 12.3 59.6 76.4 48.9 36.0 45.6 137.6 126.7 49.7 55.4 26.3 30.8 30.7 374.8 111.7 46.3 35.4 76.3 61.9 110.4 86.0 49.9 TF "PRO1557, PRO2086" ENSG00000091513 Transferrin P02787 3 133746040-133796641 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Ion transport, Iron transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "liver: 7525.8;retina: 2433.0" "Group enriched" "Detected in many" 9 "Hepatocytes: 7205.2;Muller glia cells: 12965.3" "Cancer enriched" "Detected in many" 42 "liver cancer: 783.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 48 "Hep G2: 780.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001527, HPA005692, CAB009538" Enhanced "Secreted to blood" NA NA 19800000000000 98000000000 "Cluster 17: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "CAB009538: AB_793365, HPA001527: AB_1080357, HPA005692: AB_1080354" "prognostic favorable (4.05e-4)" "unprognostic (2.45e-2)" "unprognostic (1.78e-1)" "unprognostic (1.50e-1)" "unprognostic (8.99e-2)" "unprognostic (5.18e-2)" "unprognostic (6.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.37e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (2.35e-13)" "unprognostic (2.17e-3)" "unprognostic (5.49e-2)" "unprognostic (3.47e-3)" "unprognostic (9.70e-2)" 80.9 1.2 186.3 1.0 412.5 2.4 13.3 591.8 274.2 2.0 58.9 2.3 0.9 1.7 1.4 11.0 1.4 1.9 12.1 173.7 287.7 3.4 7525.8 1.9 1.3 786.9 385.4 2.1 4.6 2.2 4.4 1.3 628.2 5.4 1.2 2433.0 55.8 1.8 2.1 4.2 1.6 1.5 484.9 2.9 1.9 14.3 398.1 1.2 2.2 2.7 3.0 1.2 2.8 862.1 1.9 1.4 1.8 1.2 5.5 3.4 0.9 1.9 2.0 1.0 0.8 3.4 1.5 1.7 1.6 1.8 1.2 2.1 1.3 1.8 1.5 1.1 0.7 16.3 2.7 780.9 1.3 4.6 2.7 2.4 3.8 1.0 1.7 1.8 2.2 0.9 6.4 2.1 2.6 1.3 1.1 1.2 1.2 1.2 1.8 1.5 2.9 1.2 1.1 3.1 1.9 1.4 2.4 2.6 7.0 1.3 1.9 1.3 2.9 2.4 1.5 1.6 1.1 1.7 3.0 1.4 2.0 1.5 1.6 0.6 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 186.3 412.5 591.8 274.2 173.7 287.7 786.9 385.4 628.2 484.9 398.1 862.1 0.7 16.0 32.4 36.2 11.4 1.0 5.6 0.6 0.0 101.3 5.3 4.3 2.7 117.2 22.9 0.0 91.8 0.2 0.2 0.1 1.9 0.7 5.4 0.8 1.0 16.7 0.0 56.2 34.2 1.1 0.3 3.9 0.0 0.6 17.7 1.3 87.4 7205.2 0.1 47.1 34.7 0.0 0.0 124.7 0.3 3.8 0.3 4.7 0.0 9.4 0.6 12965.3 0.0 45.2 1077.2 1.1 0.0 0.4 0.0 18.7 0.0 0.5 22.1 400.4 0.0 11.6 0.4 0.5 0.4 3.6 0.0 0.3 7.8 0.5 0.0 3.0 TFAP2A "AP-2, AP2TF, TFAP2" ENSG00000137203 "Transcription factor AP-2 alpha" P05549 6 10393186-10419659 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 32.8;skin 1: 66.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 167.9;Cytotrophoblasts: 285.8;Extravillous trophoblasts: 260.6;Squamous epithelial cells: 147.7;Syncytiotrophoblasts: 700.1" "Cancer enhanced" "Detected in many" "melanoma: 45.6" "Group enriched" "Detected in many" 4 "cerebellum: 4.1;medulla oblongata: 3.0;midbrain: 1.3;pons: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 104.7;hTCEpi: 97.3;SuSa: 97.3" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;pons and medulla: 1.0" "Low region specificity" "Detected in many" "CAB000326, HPA056871" Enhanced Enhanced Nucleoplasm NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "CAB000326: AB_667767, HPA056871: AB_2683262" "unprognostic (5.97e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (1.14e-1)" "unprognostic (3.87e-2)" "unprognostic (1.27e-1)" "unprognostic (7.62e-5)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.45e-1)" "unprognostic (2.76e-2)" "unprognostic (3.33e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-11)" "unprognostic (1.46e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-4)" "unprognostic (2.25e-2)" 0.5 0.4 0.4 0.1 0.3 0.1 32.8 4.1 0.4 7.5 0.2 1.1 0.5 0.3 21.8 29.9 0.4 0.2 0.9 0.3 0.1 7.4 0.1 0.5 0.4 3.0 1.3 0.4 0.2 0.6 0.4 29.6 2.1 9.8 0.5 8.1 23.5 9.3 0.5 66.7 0.8 0.1 0.5 0.1 1.4 2.2 0.5 0.2 0.5 0.1 5.1 3.5 16.6 0.6 51.8 17.8 0.1 87.9 0.4 0.0 19.7 40.2 30.3 31.7 31.4 2.1 19.3 3.2 4.9 12.0 17.5 53.2 4.3 66.1 30.9 104.7 45.2 0.4 44.5 0.0 0.0 1.7 1.5 0.0 97.3 0.1 66.6 18.3 0.0 0.9 3.3 0.1 0.3 12.2 0.0 17.2 0.5 3.3 24.7 5.9 5.0 2.2 18.8 21.8 12.5 0.3 44.1 82.7 82.3 97.3 56.0 1.7 0.0 9.9 2.7 7.1 25.3 0.1 5.1 0.8 5.1 1.7 59.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.1 0.4 0.3 0.1 3.0 1.3 2.1 0.5 0.5 0.6 0.5 0.0 0.0 0.0 0.4 130.6 45.5 50.3 167.9 25.9 98.2 65.7 2.7 0.0 30.5 31.3 2.1 285.8 0.5 1.0 7.9 2.2 5.3 1.2 0.7 2.1 1.2 0.0 0.0 0.4 260.6 4.2 0.0 1.5 0.0 0.1 0.0 0.0 20.4 80.8 0.0 0.5 46.8 0.0 6.1 3.8 0.6 0.5 124.5 0.0 0.0 4.3 0.0 0.0 0.1 3.7 0.5 0.0 1.2 58.2 0.1 0.3 21.5 4.6 0.0 0.3 4.1 6.5 16.8 147.7 138.4 700.1 0.3 0.3 0.5 46.7 TFAP2C "AP2-GAMMA, ERF1, hAP-2g, TFAP2G" ENSG00000087510 "Transcription factor AP-2 gamma" Q92754 20 56629306-56639283 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 29.1;skin 1: 53.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 132.4;Basal squamous epithelial cells: 120.1;Breast glandular cells: 66.1;Breast myoepithelial cells: 79.6;Cytotrophoblasts: 91.7;Extravillous trophoblasts: 59.7;Squamous epithelial cells: 81.0;Suprabasal keratinocytes: 149.3;Syncytiotrophoblasts: 105.6" "Cancer enhanced" "Detected in many" "testis cancer: 54.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "BEWO: 190.6;MCF7: 169.2;SK-BR-3: 308.9;T-47d: 86.8;WM-115: 114.7" "Region enriched" "Detected in single" 13 "olfactory bulb: 2.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "CAB016061, CAB016079, HPA055179, HPA057076" Enhanced Supported Nucleoplasm Yes NA "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "CAB016061: AB_667770, CAB016079: AB_2199447, HPA055179: AB_2682729, HPA057076: AB_2683329" "unprognostic (1.74e-2)" "prognostic favorable (6.90e-4)" "unprognostic (2.24e-2)" "unprognostic (2.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.75e-2)" "unprognostic (2.54e-2)" "unprognostic (8.26e-2)" "unprognostic (2.97e-1)" "unprognostic (1.61e-1)" "unprognostic (3.14e-3)" "unprognostic (2.63e-1)" "unprognostic (9.04e-5)" "unprognostic (2.31e-1)" "unprognostic (1.85e-1)" "unprognostic (6.71e-2)" "unprognostic (3.28e-2)" 1.8 0.3 1.3 0.2 0.6 0.1 26.1 0.5 1.5 18.3 0.5 4.0 0.2 6.2 5.2 29.1 2.6 1.0 0.3 1.7 0.7 2.0 0.0 2.6 0.1 0.9 0.8 0.3 1.0 2.6 0.8 17.0 1.2 7.1 1.2 2.7 20.7 4.4 2.1 53.3 0.3 1.1 0.5 0.1 0.7 1.0 0.6 0.7 2.3 0.1 3.0 3.9 19.2 1.0 12.8 15.8 0.1 0.2 0.0 0.0 190.6 20.1 36.4 25.0 4.5 3.2 0.3 0.0 1.3 13.3 13.3 42.7 27.3 5.5 17.0 0.1 2.8 0.0 1.7 0.0 0.0 0.0 1.7 0.3 21.4 7.4 7.2 0.0 0.0 8.1 0.2 3.2 0.0 169.2 20.8 1.2 9.5 9.9 20.7 0.1 0.0 7.0 0.0 10.1 5.1 0.1 13.6 308.9 21.8 28.3 86.8 4.6 0.2 16.2 0.4 8.6 15.4 0.1 0.0 0.1 4.0 0.1 114.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.5 1.5 1.7 0.7 0.9 0.8 1.2 0.5 0.6 1.0 0.7 0.0 9.5 3.9 0.3 132.4 29.9 2.4 120.1 4.1 66.1 79.6 1.0 0.0 5.6 9.2 0.0 91.7 1.5 1.7 0.0 0.3 0.3 7.8 18.7 2.0 3.0 0.0 0.0 0.0 59.7 7.4 1.5 16.0 0.0 0.0 0.7 0.0 7.8 0.0 0.0 1.7 10.2 0.3 8.2 0.0 0.0 1.6 21.4 3.7 0.0 0.3 0.0 0.0 0.0 1.0 0.6 0.0 3.8 18.6 0.0 0.0 5.2 0.0 0.0 0.5 2.1 0.0 1.8 81.0 149.3 105.6 1.3 0.0 1.0 18.5 TFAP2E AP2E ENSG00000116819 "Transcription factor AP-2 epsilon" Q6VUC0 1 35573314-35595328 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.8;Excitatory neurons: 9.0;Inhibitory neurons: 9.8;Oligodendrocytes: 11.3;Rod photoreceptor cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 4.6;SK-MEL-30: 1.7;U-937: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 24: NB-4 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (7.06e-4)" "unprognostic (1.96e-2)" "unprognostic (9.05e-2)" "unprognostic (2.29e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-2)" "unprognostic (1.05e-2)" "unprognostic (3.34e-2)" "unprognostic (3.27e-2)" "unprognostic (9.39e-2)" "unprognostic (4.02e-1)" "unprognostic (7.45e-2)" "unprognostic (1.67e-15)" "unprognostic (2.03e-1)" "unprognostic (4.83e-1)" "unprognostic (3.48e-2)" "unprognostic (7.40e-2)" 1.0 0.6 3.0 0.9 2.8 1.5 1.0 9.2 4.0 3.5 0.2 1.1 0.1 1.3 0.3 1.2 2.5 0.2 0.9 2.6 2.2 1.1 0.3 1.3 0.9 2.8 2.3 2.5 0.6 0.0 3.2 0.2 3.0 1.7 0.1 4.4 1.0 0.1 0.4 5.2 1.2 0.0 2.4 1.9 1.0 2.2 2.4 0.3 0.5 0.0 0.3 0.8 3.1 5.1 0.2 0.2 0.2 0.1 0.1 0.1 0.8 0.1 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.6 0.2 0.5 0.4 0.3 0.0 0.0 0.6 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.3 4.6 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.1 1.7 0.1 0.4 1.4 0.1 0.1 0.7 0.4 0.1 0.8 0.4 0.0 0.1 3.6 0.5 0.5 0.8 0.5 0.9 0.3 0.3 0.4 0.5 0.8 0.4 0.4 0.2 0.8 0.0 0.9 0.4 0.3 0.8 0.5 3.0 2.8 9.2 4.0 2.6 2.2 2.8 2.3 3.0 2.4 2.4 5.1 0.2 0.0 1.3 4.9 0.2 3.7 0.1 0.3 0.0 9.8 0.5 0.5 0.4 0.0 0.8 0.0 2.1 0.4 0.9 0.1 0.0 0.2 0.5 0.3 0.4 0.3 0.0 0.0 9.0 0.0 0.0 0.4 2.6 0.5 0.0 0.1 0.4 0.2 1.0 0.0 9.8 0.0 0.0 1.0 0.0 1.0 2.1 0.6 1.8 1.9 0.5 0.3 3.1 3.5 11.3 0.2 0.3 0.7 0.3 0.1 0.1 0.0 0.2 5.6 0.0 0.2 0.4 2.4 0.4 0.0 4.4 0.1 0.9 0.1 0.4 0.2 TFAP4 "AP-4, bHLHc41" ENSG00000090447 "Transcription factor AP-4" Q01664 16 4257186-4273075 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.1;Proximal enterocytes: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001912 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Mitochondria" "HPA001912: AB_1080251" "unprognostic (1.61e-2)" "unprognostic (1.36e-1)" "unprognostic (5.10e-2)" "unprognostic (4.42e-3)" "unprognostic (8.61e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (8.05e-2)" "unprognostic (8.97e-2)" "unprognostic (4.60e-1)" "unprognostic (5.75e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (4.31e-6)" "unprognostic (1.08e-2)" "unprognostic (3.25e-1)" "unprognostic (2.39e-2)" "unprognostic (1.30e-1)" 6.2 4.2 3.7 6.9 3.8 1.9 5.8 5.3 5.4 9.0 1.7 5.4 6.4 7.8 1.0 8.1 6.9 3.8 3.2 3.5 3.2 3.6 5.3 3.9 6.8 3.9 3.7 10.0 12.0 3.3 4.3 3.7 3.9 5.7 1.9 0.7 7.6 3.1 7.5 10.5 6.8 2.5 3.5 7.3 5.0 1.7 3.7 8.3 4.6 3.1 3.9 6.4 8.4 5.1 14.9 15.4 12.9 19.2 5.4 14.1 21.7 5.7 14.6 9.6 10.5 8.1 23.0 51.0 14.5 5.5 4.5 22.0 23.6 19.4 3.0 29.8 17.4 15.6 13.0 21.1 7.5 27.8 8.8 13.3 12.2 10.4 29.0 4.5 6.4 16.7 29.1 13.1 3.8 23.9 39.2 46.4 29.8 14.7 20.2 34.3 28.8 53.7 3.7 11.2 27.0 20.0 19.2 19.7 18.9 2.0 10.0 21.9 4.2 13.1 10.4 46.2 15.1 21.3 19.3 43.6 8.8 27.2 9.5 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.7 3.8 5.3 5.4 3.5 3.2 3.9 3.7 3.9 3.5 3.7 5.1 7.0 3.2 0.0 2.3 11.6 21.5 9.8 5.7 30.1 4.2 8.1 6.6 2.2 7.2 2.1 27.6 0.0 7.7 5.3 5.3 7.9 4.1 0.1 2.4 9.6 5.4 7.8 22.7 3.0 5.7 11.7 7.6 10.7 3.1 0.0 6.9 3.6 3.4 4.2 0.0 3.9 12.4 8.2 4.0 7.4 0.1 11.8 3.7 3.6 1.0 4.7 2.2 5.2 1.5 3.6 2.9 5.3 5.3 7.2 11.1 40.0 5.7 1.4 3.4 6.6 6.9 7.1 0.9 0.9 22.1 22.3 2.2 7.3 7.5 20.2 4.3 TFDP1 "DILC, Dp-1, DP1, DRTF1" ENSG00000198176 "Transcription factor Dp-1" Q14186 13 113584721-113641473 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 164.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 344.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 31.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 31.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033605, HPA044754, HPA068909, HPA077304" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "Nuclear membrane, Cytosol" "CAB033605: AB_783105, HPA044754: AB_2679074, HPA068909: AB_2686056, HPA077304: " "unprognostic (4.28e-2)" "unprognostic (9.50e-3)" "unprognostic (1.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.01e-2)" "unprognostic (2.10e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (5.50e-3)" "unprognostic (1.68e-2)" "unprognostic (3.96e-1)" "unprognostic (2.04e-2)" "unprognostic (2.43e-2)" "prognostic favorable (7.57e-4)" "prognostic favorable (6.17e-4)" "unprognostic (2.30e-1)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" 28.2 23.5 24.3 38.6 24.0 164.0 27.2 24.5 24.4 33.5 32.5 37.8 30.5 27.6 19.4 50.1 32.8 24.6 34.3 24.1 22.8 23.2 25.9 21.8 67.1 27.5 24.4 19.3 18.4 28.5 21.3 40.6 25.3 26.1 42.4 20.2 26.1 30.8 58.2 42.8 32.3 34.3 26.6 30.8 31.3 49.6 26.8 53.4 33.1 59.0 68.3 37.5 30.1 25.7 343.2 82.5 104.4 89.5 138.4 122.7 118.5 187.8 168.7 238.1 218.6 173.3 155.9 314.6 61.3 181.3 130.3 160.3 183.0 167.1 232.2 215.9 212.8 184.4 129.2 109.8 86.8 468.3 155.7 102.1 147.3 151.3 87.4 85.0 162.7 116.2 154.1 82.6 215.5 117.7 207.0 181.4 96.6 322.7 105.0 138.9 93.0 181.1 91.3 129.1 268.2 79.3 84.8 228.8 58.7 75.1 157.9 371.7 114.4 77.2 122.9 165.6 210.8 69.5 92.4 326.4 171.9 285.2 133.2 31.9 3.0 4.6 3.1 3.8 3.4 4.4 4.1 3.7 5.9 3.6 6.3 3.2 3.8 2.3 5.5 3.0 5.3 2.5 24.3 24.0 24.5 24.4 24.1 22.8 27.5 24.4 25.3 26.6 26.8 25.7 21.4 9.6 15.8 12.7 38.8 59.8 32.1 16.1 33.6 10.3 45.6 35.2 26.6 28.6 14.7 29.5 14.6 83.2 33.8 29.8 80.3 12.3 5.5 34.4 28.2 25.8 40.2 344.3 22.5 11.9 128.0 30.8 38.7 31.0 21.0 23.3 34.6 58.7 49.2 6.7 19.5 36.1 12.2 49.1 51.2 10.7 28.6 41.1 35.6 5.6 24.8 14.7 16.5 9.5 10.2 19.0 24.2 28.2 67.3 35.7 29.4 66.5 21.0 22.5 6.6 20.0 32.7 76.7 52.7 74.6 60.0 66.6 32.1 30.3 47.4 35.8 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 713.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Basal respiratory cells: 63.6;Club cells: 18.8;Distal tubular cells: 29.4;Squamous epithelial cells: 34.7" "Group enriched" "Detected in many" 4 "cervical cancer: 30.8;head and neck cancer: 78.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.5;HaCaT: 24.2;HeLa: 16.2;MCF7: 17.5;SK-BR-3: 21.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171, HPA070372" Enhanced Approved "Vesicles,Plasma membrane" NA NA 530000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB015159: AB_2202870, HPA040171: AB_2676869, HPA070372: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 25.7 1.3 0.6 0.9 0.8 0.7 2.2 3.7 2.0 78.7 0.8 1.4 0.8 1.0 1.6 713.5 4.4 0.6 5.1 0.5 0.6 2.5 1.7 5.3 1.5 1.5 0.9 3.0 3.2 0.2 3.3 1.2 1.4 4.1 0.9 1.7 89.7 4.4 1.1 73.2 1.9 0.5 0.4 2.6 1.8 2.9 0.9 1.3 2.7 0.3 40.4 1.3 144.2 0.9 1.1 2.0 1.1 1.0 0.0 0.8 17.5 0.4 0.2 1.0 1.6 1.2 1.7 1.0 2.3 1.3 0.3 24.2 2.8 2.0 0.6 2.0 3.3 1.4 16.2 5.7 0.8 0.9 1.5 1.5 9.3 0.5 2.0 0.5 0.7 3.4 1.0 1.0 0.7 17.5 0.7 1.9 0.3 1.1 2.2 1.1 0.1 1.1 0.6 2.1 1.2 1.6 0.2 21.7 0.1 1.4 1.5 1.1 0.8 1.1 4.8 2.0 0.9 1.5 1.8 0.3 0.4 2.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 3.7 2.0 0.5 0.6 1.5 0.9 1.4 0.4 0.9 0.9 0.2 12.8 1.1 2.0 0.0 0.3 4.6 63.6 4.0 0.9 1.1 0.8 0.8 5.7 18.8 0.0 0.0 1.4 0.3 0.2 29.4 2.0 0.1 0.3 0.2 0.2 0.0 0.0 1.5 0.9 0.8 3.9 0.0 0.6 4.5 0.7 0.0 0.2 0.4 0.0 1.7 0.1 6.1 0.6 0.3 0.0 0.6 0.4 0.0 1.0 0.4 0.2 0.0 1.0 1.0 2.6 0.0 0.4 0.1 7.4 0.1 0.2 2.1 0.6 0.0 0.1 1.0 0.0 0.6 34.7 1.8 1.2 0.6 1.2 0.3 6.2 TGM7 TGMZ ENSG00000159495 "Transglutaminase 7" Q96PF1 15 43276271-43302255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.6" "Group enriched" "Detected in some" 11 "Early spermatids: 62.0;Late spermatids: 16.7" "Cancer enriched" "Detected in single" 13 "endometrial cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 35 "EFO-21: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 16: Immune cells - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (2.45e-2)" "unprognostic (2.04e-1)" "unprognostic (2.82e-2)" "unprognostic (1.71e-2)" "unprognostic (1.07e-1)" "unprognostic (2.01e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 3.5 THAP11 "CTG-B43a, CTG-B45d, HRIHFB2206, RONIN" ENSG00000168286 "THAP domain containing 11" Q96EK4 16 67842320-67844195 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041434, HPA042189, HPA072537" Supported Supported Nucleoplasm,Cytosol NA No "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Nucleoplasm Cytosol "HPA041434: AB_10960385, HPA042189: AB_10964636, HPA072537: " "unprognostic (1.43e-1)" "unprognostic (2.51e-1)" "unprognostic (2.82e-1)" "unprognostic (1.54e-3)" "unprognostic (1.93e-3)" "unprognostic (1.40e-2)" "unprognostic (1.56e-3)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (2.34e-1)" "unprognostic (1.66e-1)" "unprognostic (9.51e-2)" "unprognostic (2.97e-1)" "unprognostic (2.11e-1)" "unprognostic (2.10e-2)" "unprognostic (4.59e-2)" "unprognostic (5.87e-2)" 16.6 14.4 20.5 14.9 21.1 10.2 16.3 21.4 21.3 21.9 19.2 26.7 12.3 24.5 13.0 19.5 22.4 10.1 25.1 20.7 21.7 16.1 14.9 15.4 20.8 22.1 20.8 20.9 19.3 16.9 16.4 12.3 20.6 16.1 11.1 10.9 15.7 19.6 48.1 26.1 22.1 17.2 22.5 24.8 20.8 12.6 21.1 23.5 14.9 26.4 19.0 23.9 18.4 23.1 31.3 40.2 27.4 25.9 37.5 25.7 28.7 15.5 27.0 37.1 31.9 51.9 23.6 68.0 31.7 15.9 22.3 35.6 48.6 29.0 21.1 25.4 55.3 27.1 22.5 64.1 34.2 34.9 29.4 23.6 28.4 25.6 22.4 26.8 27.7 45.9 39.5 15.4 22.9 49.1 37.7 62.6 55.1 36.9 34.7 73.6 32.7 61.4 19.0 20.2 38.2 43.1 45.4 16.4 33.2 19.6 40.1 35.2 22.3 23.4 28.4 21.3 19.2 60.9 65.9 67.5 18.3 38.2 25.8 7.6 13.6 14.7 26.3 18.4 20.7 13.8 23.6 24.2 14.3 18.8 29.9 24.0 4.1 21.3 17.5 11.3 31.5 17.9 20.5 21.1 21.4 21.3 20.7 21.7 22.1 20.8 20.6 22.5 21.1 23.1 20.4 22.4 13.1 3.3 24.4 29.2 25.0 6.6 22.8 25.6 27.4 23.6 15.1 12.8 5.3 11.0 4.2 19.6 32.8 12.5 52.8 7.6 1.2 18.6 18.0 21.3 13.2 23.8 4.6 9.5 25.9 17.4 7.1 14.3 7.6 20.3 24.3 14.0 22.4 8.4 4.6 16.2 6.1 19.6 20.0 2.2 23.6 19.1 10.6 4.7 24.5 29.8 43.3 7.1 6.1 6.5 5.9 31.2 18.9 25.0 13.5 19.8 6.1 16.9 19.7 24.2 22.2 16.1 27.4 20.9 39.1 13.5 32.5 28.6 16.5 20.2 THAP8 FLJ32891 ENSG00000161277 "THAP domain containing 8" Q8NA92 19 36034984-36054739 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 18.8;Spermatogonia: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA064056, HPA070139" Approved Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA064056: AB_2685184, HPA070139: AB_2686230" "unprognostic (1.33e-3)" "unprognostic (2.24e-1)" "unprognostic (8.03e-2)" "unprognostic (1.08e-2)" "unprognostic (3.10e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (9.01e-3)" "unprognostic (3.94e-1)" "unprognostic (1.27e-1)" "prognostic favorable (3.19e-4)" "unprognostic (2.50e-1)" "unprognostic (2.10e-2)" "unprognostic (9.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.48e-2)" "unprognostic (2.48e-1)" 3.3 3.2 9.1 2.5 9.8 0.9 2.7 9.4 9.6 5.0 6.3 9.5 3.7 4.7 3.4 3.7 3.8 3.5 3.5 8.3 9.7 4.1 4.6 2.8 3.1 10.1 9.8 3.5 2.8 3.7 3.4 2.8 10.2 3.6 2.4 4.6 3.0 4.3 10.2 5.2 3.5 4.4 8.9 3.4 3.6 9.7 9.7 4.0 3.1 3.3 2.2 6.6 4.0 11.2 3.3 8.2 4.4 3.7 11.6 8.0 2.8 2.7 4.8 5.5 7.8 3.6 2.3 4.5 9.7 4.5 5.7 1.5 2.5 3.3 2.1 3.2 1.6 2.8 3.0 4.3 12.7 1.6 2.7 6.2 5.0 3.8 2.6 6.2 2.6 8.2 2.4 5.3 5.8 5.5 4.1 3.4 3.9 5.6 3.1 3.9 1.4 4.2 4.5 2.9 8.1 6.1 4.6 3.9 3.3 5.7 4.1 2.2 2.3 7.3 4.5 4.5 2.2 5.2 4.5 3.3 8.0 2.6 4.7 7.1 6.5 7.9 5.2 7.6 5.9 4.1 5.5 5.4 4.7 3.0 4.1 6.1 2.7 6.2 6.6 4.5 5.8 4.1 9.1 9.8 9.4 9.6 8.3 9.7 10.1 9.8 10.2 8.9 9.7 11.2 1.4 3.2 3.7 3.6 3.4 1.1 1.2 3.2 2.8 2.2 3.0 2.4 3.7 5.7 2.9 7.3 2.1 10.2 3.5 2.1 1.9 5.7 3.0 1.5 3.9 2.5 6.6 1.3 2.7 0.5 5.5 3.8 4.1 2.7 5.7 8.8 3.9 3.5 15.8 3.3 3.3 1.3 12.2 4.4 0.8 6.1 1.8 3.2 1.8 1.9 4.4 5.2 8.2 4.5 5.5 2.6 2.7 4.1 2.5 1.2 5.3 11.7 1.2 3.0 0.0 1.7 2.9 18.8 21.5 2.3 2.3 10.5 2.5 5.8 2.2 1.0 THEM5 FLJ37964 ENSG00000196407 "Thioesterase superfamily member 5" Q8N1Q8 1 151847101-151853712 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "skin 1: 158.5" "Cell type enriched" "Detected in some" 18 "Suprabasal keratinocytes: 34.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.1;cerebral cortex: 4.0;hippocampal formation: 3.0;white matter: 1.0" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 1.7" "Cell line enriched" "Detected in some" 7 "HDLM-2: 57.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "basal ganglia: 13.8" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 28: Keratinocytes - Keratinization" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (3.41e-2)" "unprognostic (2.58e-3)" "unprognostic (9.55e-3)" "unprognostic (1.27e-1)" "unprognostic (1.93e-1)" "unprognostic (1.83e-1)" "unprognostic (7.86e-3)" "unprognostic (3.07e-3)" "unprognostic (9.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.34e-2)" "unprognostic (1.62e-2)" 0.3 1.9 2.1 2.0 0.3 0.5 4.2 0.0 4.0 1.6 0.5 0.4 1.4 0.5 0.0 6.5 0.7 3.1 1.9 3.0 0.0 1.1 0.6 1.3 6.3 0.3 0.0 0.2 1.3 0.0 0.5 0.5 0.2 0.4 0.0 0.7 3.1 0.0 1.3 158.5 0.8 0.0 0.0 1.0 1.9 1.2 0.6 0.1 1.0 0.0 0.3 1.2 3.2 1.0 6.6 0.0 0.1 0.2 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 2.3 0.0 0.0 0.0 57.6 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.3 0.0 1.7 0.2 0.0 7.1 1.2 0.6 0.0 0.2 0.7 0.0 0.0 0.4 0.1 8.6 2.1 1.1 1.4 1.4 2.4 0.0 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.7 0.1 1.7 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.9 1.7 2.1 0.3 0.0 4.0 3.0 0.0 0.3 0.0 0.2 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.8 34.7 1.1 0.0 0.0 0.0 0.0 THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 47.1;Microglial cells: 15.0;T-cells: 59.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 22 "gdT-cell: 26.7;MAIT T-cell: 34.0;memory CD4 T-cell: 33.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.0;naive CD8 T-cell: 58.3" "Lineage enriched" "Detected in single" 88 "T-cells: 58.3" "Group enriched" "Detected in some" 4 "HDLM-2: 32.6;JURKAT: 54.1;MOLT-4: 51.6;RPMI-8226: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Cytosol Nucleoplasm "HPA031422: AB_2673874, HPA031425: AB_10670129" "unprognostic (1.47e-4)" "unprognostic (2.50e-3)" "unprognostic (1.31e-2)" "unprognostic (1.41e-4)" "unprognostic (1.41e-1)" "unprognostic (5.20e-3)" "unprognostic (7.48e-3)" "unprognostic (9.01e-3)" "unprognostic (1.47e-1)" "unprognostic (7.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-4)" "unprognostic (2.04e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-2)" 0.4 0.5 0.5 3.3 3.2 1.7 0.6 0.1 2.3 0.4 0.3 0.7 1.6 0.2 0.4 0.6 0.2 1.4 0.1 0.9 0.1 0.2 0.7 1.4 7.5 0.6 0.3 0.1 0.3 0.0 0.0 0.1 0.4 0.4 0.9 0.0 0.9 0.1 0.1 0.2 2.3 0.3 0.3 3.2 1.5 0.1 0.3 32.9 0.4 0.1 4.0 1.1 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 26.7 0.1 34.0 0.1 33.5 48.9 0.2 0.2 30.0 58.3 0.6 0.1 0.2 0.2 1.7 20.3 0.5 3.2 0.1 2.3 0.9 0.1 0.6 0.3 0.4 0.3 0.3 1.9 0.5 0.0 3.0 2.9 2.0 0.5 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.9 0.1 0.2 0.4 0.0 1.7 47.1 0.0 0.0 0.7 5.1 0.1 1.3 0.0 1.1 0.1 0.1 0.0 0.9 0.0 0.0 0.8 0.8 0.2 0.0 1.5 7.2 15.0 1.4 0.0 0.0 0.0 9.7 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.1 1.4 0.0 59.9 0.0 0.0 0.1 THRSP "Lpgp, LPGP1, S14, SPOT14, THRP" ENSG00000151365 "Thyroid hormone responsive" Q92748 11 78063861-78068351 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 210.0;liver: 408.9" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 128.4" "Cancer enhanced" "Detected in many" "liver cancer: 44.1" "Region enriched" "Detected in single" 6 "cerebellum: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "ASC diff: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040642 Approved Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm "HPA040642: AB_10794878" "unprognostic (1.19e-1)" "unprognostic (2.88e-1)" "unprognostic (2.84e-1)" "unprognostic (2.73e-2)" "unprognostic (3.07e-1)" "unprognostic (9.91e-3)" "unprognostic (1.59e-2)" "unprognostic (9.60e-2)" "unprognostic (1.07e-2)" "unprognostic (8.23e-2)" "unprognostic (1.68e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (9.64e-2)" "unprognostic (1.57e-1)" "prognostic favorable (3.28e-4)" "unprognostic (1.69e-3)" 210.0 5.9 0.1 0.4 0.1 0.0 95.3 2.7 0.3 0.1 0.0 2.6 0.0 0.1 0.4 0.3 1.0 3.4 18.6 0.2 0.0 4.6 408.9 0.1 0.7 0.0 0.2 0.1 3.6 15.5 0.1 0.0 0.4 0.1 0.2 1.5 48.9 2.3 8.2 33.7 4.6 0.5 0.0 0.1 0.7 0.1 0.0 0.2 5.7 3.3 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.0 76.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 2.7 0.3 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.8 0.1 0.1 0.0 0.0 2.3 21.1 11.2 0.1 4.3 0.0 0.0 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.6 0.1 0.4 0.0 2.7 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.1 2.9 128.4 0.0 0.0 0.4 0.3 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.1 THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.5" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Bipolar cells: 183.8;Horizontal cells: 208.6;Inhibitory neurons: 494.3;Oligodendrocyte precursor cells: 262.4" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 54 "basophil: 5.3" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.3" "Cell line enhanced" "Detected in some" "A549: 10.3;HUVEC TERT2: 6.7;REH: 7.1;SH-SY5Y: 10.2;THP-1: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" NA NA 6100000 "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" 2.4 0.7 2.9 0.7 2.3 0.0 2.1 3.2 4.4 3.3 0.0 1.0 0.3 2.8 0.8 0.5 2.1 2.6 0.7 4.2 3.5 7.5 0.6 1.1 0.3 2.8 4.9 2.5 0.4 1.2 1.6 4.1 2.5 3.4 0.7 5.0 0.5 2.1 0.2 0.5 0.5 2.4 3.4 0.9 0.5 0.8 4.8 0.2 1.9 1.2 0.2 1.8 1.7 2.4 0.0 10.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 7.1 0.0 0.0 0.3 0.1 0.7 10.2 0.0 0.3 0.0 1.6 0.1 19.2 3.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 3.2 4.4 4.2 3.5 2.8 4.9 2.5 3.4 4.8 2.4 46.9 22.4 8.2 150.5 0.0 2.7 1.4 0.0 1.2 183.8 0.8 0.5 1.5 21.5 2.8 55.2 112.6 23.5 0.1 0.4 7.9 7.0 1.2 4.9 22.4 42.6 41.7 0.0 56.6 2.2 4.3 8.1 0.5 18.8 0.0 6.1 28.2 1.3 2.2 208.6 494.3 0.8 0.0 1.5 2.9 0.5 24.2 0.5 12.4 105.9 0.0 20.7 0.0 262.4 5.4 5.5 6.8 1.5 0.1 7.7 0.1 8.8 0.1 9.3 0.0 10.6 5.0 1.6 1.1 0.6 2.4 51.9 0.8 21.5 1.2 1.1 THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.6;Excitatory neurons: 116.0;Fibroblasts: 201.9;Inhibitory neurons: 104.1;Muller glia cells: 108.1;Proximal tubular cells: 199.9;Smooth muscle cells: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 461.3;BJ: 738.4;BJ hTERT+: 832.5;fHDF/TERT166: 1330.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" 90.6 16.4 97.9 78.6 114.8 0.2 25.6 12.9 286.8 78.9 0.0 35.4 10.2 58.6 27.8 29.4 23.1 101.0 12.9 135.4 73.3 142.2 7.4 21.6 40.4 83.6 37.0 9.2 14.8 39.4 18.1 62.0 60.8 15.5 41.8 25.3 8.5 47.0 3.4 13.9 14.5 304.7 35.4 21.9 17.4 11.4 43.6 73.2 37.9 8.3 35.6 216.7 21.7 108.7 0.7 3.9 108.5 0.1 461.3 331.5 0.3 738.4 832.5 263.6 289.3 0.2 0.2 0.4 0.1 1330.6 121.9 0.9 4.3 1.1 200.7 65.1 0.0 41.5 14.4 0.0 142.7 0.0 0.2 247.5 0.0 335.6 11.6 355.2 0.3 22.6 0.0 0.6 206.5 0.1 0.6 0.1 173.9 0.0 1.4 0.5 50.7 0.3 0.1 0.2 18.1 47.9 0.1 0.4 0.2 32.9 1.0 2.1 0.0 368.6 120.9 107.3 110.1 0.3 19.7 0.4 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.9 114.8 12.9 286.8 135.4 73.3 83.6 37.0 60.8 35.4 43.6 108.7 68.2 0.0 1.8 17.3 2.1 17.7 0.3 1.7 0.0 27.2 1.6 40.0 0.9 0.0 0.0 9.2 0.0 1.9 0.2 0.0 21.5 0.9 1.0 5.1 141.6 69.2 0.0 0.0 116.0 0.0 2.6 201.9 1.5 3.2 1.3 0.0 17.5 0.1 4.0 32.0 104.1 0.0 0.0 0.0 25.0 2.7 96.3 2.7 17.8 21.5 0.0 108.1 0.0 64.3 22.7 0.4 0.0 77.5 0.1 0.3 0.0 199.9 0.0 27.5 32.9 9.3 226.6 0.3 0.6 0.2 17.6 4.0 4.5 6.2 0.0 0.6 TICRR "C15orf42, FLJ41618, MGC45866, SLD3, Treslin" ENSG00000140534 "TOPBP1 interacting checkpoint and replication regulator" Q7Z2Z1 15 89575469-89631056 "Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.4;esophagus: 4.2;lymphoid tissue: 4.2" "Cell type enhanced" "Detected in some" "Erythroid cells: 6.5;Extravillous trophoblasts: 6.0;Granulosa cells: 5.1;Spermatocytes: 5.4;Spermatogonia: 5.3;Squamous epithelial cells: 8.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046746, HPA049454" Supported Nucleoplasm NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA046746: AB_2732533, HPA049454: AB_2680773" "unprognostic (3.52e-2)" "unprognostic (1.41e-1)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (3.41e-1)" "unprognostic (1.10e-1)" "unprognostic (6.22e-5)" "unprognostic (7.73e-3)" "prognostic unfavorable (2.87e-6)" "unprognostic (1.64e-1)" "unprognostic (1.31e-4)" "unprognostic (5.87e-2)" "unprognostic (0.00e+0)" "unprognostic (3.54e-2)" "unprognostic (7.38e-2)" "unprognostic (4.53e-2)" "unprognostic (3.59e-2)" 0.3 0.1 0.1 1.0 0.1 3.4 0.3 0.0 0.0 0.5 0.0 0.8 1.0 0.4 0.0 4.2 0.3 0.1 0.1 0.0 0.0 0.1 0.1 0.2 1.4 0.1 0.0 0.3 0.0 0.0 0.1 0.9 0.0 0.2 1.1 0.1 0.5 0.0 0.0 0.5 0.9 0.2 0.1 0.5 0.4 1.5 0.2 4.2 0.1 0.0 1.8 0.3 1.1 0.0 11.0 15.0 19.0 11.0 0.7 1.5 10.7 8.0 3.7 11.0 11.4 16.4 8.4 14.7 4.2 2.6 9.2 21.5 26.3 7.0 10.0 7.4 25.4 21.9 15.5 8.7 0.1 15.8 7.6 0.4 0.5 9.0 6.6 1.6 5.5 12.8 21.3 16.6 6.4 10.4 13.9 13.3 12.7 11.0 7.6 19.6 17.1 11.8 2.6 15.5 8.1 8.0 19.0 10.6 3.1 13.9 7.9 10.5 3.3 11.9 14.8 24.4 16.5 3.9 8.0 12.3 4.1 13.2 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.2 1.2 0.0 0.3 0.8 1.4 0.0 0.0 0.0 0.0 2.0 0.0 1.4 0.0 0.0 1.7 0.1 0.3 0.3 0.0 6.5 0.4 0.0 6.0 0.5 2.0 0.3 0.0 5.1 0.0 0.0 1.3 0.0 0.6 1.6 0.0 0.0 0.7 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.2 0.1 0.0 2.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 5.4 5.3 8.6 0.1 1.0 0.1 0.1 1.6 0.1 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 130.8;Endothelial cells: 108.8;Hepatic stellate cells: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in some" 4 "EFO-21: 106.3;HUVEC TERT2: 238.4;TIME: 210.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 47.0 10.1 16.6 8.1 14.8 0.9 37.8 14.6 16.9 14.0 10.1 11.2 5.2 20.4 5.3 6.5 16.0 13.3 34.2 13.1 14.2 19.8 6.7 35.3 10.1 16.4 16.5 7.5 4.2 3.2 8.0 48.6 16.8 10.8 3.1 0.4 7.4 6.5 14.0 7.9 11.0 14.1 13.9 19.9 8.8 3.0 21.1 2.1 24.2 20.7 2.9 15.1 11.8 14.8 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 106.3 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 41.9 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.7 238.4 0.0 0.0 0.0 0.0 0.0 0.0 20.4 1.3 0.0 0.1 8.1 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.1 210.0 1.2 0.4 0.0 0.2 0.0 0.2 0.4 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 16.6 14.8 14.6 16.9 13.1 14.2 16.4 16.5 16.8 13.9 21.1 14.8 130.8 0.0 4.2 0.0 0.4 2.2 0.6 0.0 1.2 0.3 1.0 0.9 4.9 1.5 1.8 0.0 0.0 0.3 0.7 0.9 0.0 0.0 2.0 0.1 0.4 108.8 0.0 2.5 0.4 0.2 0.1 3.1 0.0 0.4 20.3 0.1 128.8 1.3 0.5 0.0 0.2 0.1 0.0 5.6 3.1 2.5 2.1 1.1 1.8 29.0 0.1 0.1 1.0 1.0 1.1 0.0 0.0 0.7 0.1 0.7 0.1 0.9 3.6 0.9 0.0 2.2 2.2 0.9 0.7 0.5 1.4 0.3 2.3 0.5 0.2 0.7 TIGD5 FLJ14926 ENSG00000179886 "Tigger transposable element derived 5" Q53EQ6 8 143597831-143603224 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.9;Theca cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.90e-1)" "unprognostic (7.91e-2)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.22e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (2.79e-2)" "unprognostic (1.12e-1)" "unprognostic (6.72e-2)" "unprognostic (2.75e-3)" "unprognostic (3.16e-1)" "prognostic favorable (9.16e-5)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (2.32e-1)" "unprognostic (4.04e-1)" 2.1 2.9 1.8 0.2 1.6 0.1 2.1 4.0 2.0 3.0 0.5 3.1 0.4 3.2 0.1 3.5 3.0 0.2 3.6 1.5 1.6 3.0 2.3 1.7 0.3 2.1 2.0 4.0 5.9 0.7 3.8 0.1 1.7 3.0 0.1 0.1 2.7 0.3 4.4 3.7 2.7 0.1 1.5 3.6 3.0 1.5 1.7 0.2 3.0 0.4 0.2 3.2 2.5 2.0 0.9 1.5 0.4 1.2 0.6 0.6 0.6 0.5 0.4 0.5 0.4 0.5 0.6 1.7 2.7 0.4 0.5 1.2 0.4 0.4 0.0 5.9 1.8 1.0 1.7 0.2 1.1 0.4 1.4 0.6 1.1 0.3 0.5 0.7 0.4 0.4 1.2 0.2 0.2 1.6 2.9 1.7 0.6 1.0 2.9 1.1 0.3 0.8 0.5 0.6 1.4 1.8 1.1 0.9 1.2 0.1 2.6 1.2 0.7 1.0 0.8 1.0 3.5 0.9 0.4 0.2 0.6 0.7 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 1.6 4.0 2.0 1.5 1.6 2.1 2.0 1.7 1.5 1.7 2.0 5.0 3.2 1.3 0.7 3.8 1.7 5.4 0.9 1.2 16.0 6.3 4.6 5.9 4.3 1.3 5.5 20.9 1.4 4.9 5.1 0.0 2.3 1.0 4.0 8.1 4.4 0.0 4.0 0.8 1.8 1.3 4.2 2.0 5.5 1.3 15.4 4.6 2.6 3.4 16.8 1.1 3.6 0.0 3.2 0.8 0.7 7.8 3.0 0.0 1.0 3.2 10.0 6.2 0.5 0.4 3.6 1.7 4.5 1.0 4.9 3.3 2.2 1.1 15.1 0.0 10.6 4.2 0.8 1.2 2.4 1.0 1.8 3.5 29.3 5.1 3.8 TIGIT "DKFZp667A205, FLJ39873, VSIG9, VSTM3" ENSG00000181847 "T cell immunoreceptor with Ig and ITIM domains" Q495A1 3 114276913-114310288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 38.7" "Group enriched" "Detected in some" 10 "dendritic cells: 64.2;NK-cells: 69.0;T-cells: 78.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 195.5" "Lineage enriched" "Detected in many" 11 "T-cells: 195.5" "Cell line enhanced" "Detected in single" "HDLM-2: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.24e-2)" "prognostic favorable (5.43e-4)" "unprognostic (1.22e-3)" "unprognostic (2.22e-6)" "unprognostic (9.84e-2)" "prognostic favorable (3.96e-4)" "unprognostic (1.18e-1)" "unprognostic (2.57e-2)" "unprognostic (5.50e-4)" "unprognostic (3.51e-3)" "unprognostic (1.78e-1)" "unprognostic (3.15e-1)" "unprognostic (2.30e-8)" "unprognostic (3.54e-2)" "unprognostic (1.33e-1)" "unprognostic (7.62e-2)" "unprognostic (6.18e-3)" 0.7 0.3 0.3 12.1 0.5 2.1 0.7 0.6 0.5 0.8 0.2 2.1 1.7 0.9 0.7 2.1 0.5 3.6 0.7 0.4 0.4 0.4 2.9 2.9 38.7 0.8 0.5 0.5 0.2 0.1 0.2 0.3 0.7 1.4 2.4 0.3 1.8 0.2 0.1 1.0 5.2 0.9 0.4 15.0 3.7 0.8 0.7 9.0 0.9 0.0 20.4 5.1 0.5 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.5 0.0 0.2 0.1 0.0 0.4 0.2 0.1 29.8 0.2 3.5 1.4 48.5 90.3 0.2 0.9 5.2 39.8 0.7 17.3 0.2 1.0 195.5 22.0 0.3 0.5 0.6 0.5 0.4 0.4 0.8 0.5 0.7 0.4 0.7 0.9 0.9 0.0 3.3 0.0 3.7 3.1 0.1 0.0 0.6 0.4 0.4 0.6 0.6 0.0 1.3 0.0 2.1 0.1 64.2 0.0 0.0 0.0 0.0 0.2 1.0 0.6 0.0 0.4 0.0 0.0 0.0 0.9 2.6 0.4 1.3 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 1.8 4.2 0.3 0.0 2.3 3.6 0.0 0.9 0.1 69.0 0.0 0.1 0.0 0.0 0.0 6.9 0.2 0.0 0.1 0.0 0.6 0.0 1.0 0.5 0.7 3.0 0.2 3.3 0.0 78.4 0.0 0.2 0.0 TIMELESS "hTIM, TIM, TIM1" ENSG00000111602 "Timeless circadian regulator" Q9UNS1 12 56416363-56449426 "Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.5;Spermatogonia: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA060655 Enhanced Supported Nucleoplasm No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA060655: AB_2684338" "unprognostic (3.94e-2)" "unprognostic (1.10e-2)" "unprognostic (1.29e-2)" "unprognostic (2.18e-2)" "unprognostic (2.36e-1)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (1.43e-3)" "prognostic unfavorable (1.06e-5)" "unprognostic (7.03e-2)" "unprognostic (2.53e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (9.47e-3)" "unprognostic (1.72e-1)" "unprognostic (1.92e-2)" "unprognostic (5.01e-2)" 3.4 3.4 1.6 11.0 2.1 22.0 4.5 2.1 2.1 4.1 2.7 6.7 6.0 4.4 2.5 6.8 3.1 3.3 1.8 1.5 2.1 3.8 9.8 4.1 15.3 2.4 2.4 1.9 5.0 5.9 5.4 8.7 2.5 3.2 8.5 13.7 3.9 3.4 3.4 5.5 6.2 5.6 2.1 6.8 5.5 6.2 2.6 19.8 4.7 1.6 17.9 4.7 3.9 2.5 39.4 89.1 111.4 51.9 9.9 9.9 62.8 41.9 25.3 58.3 46.0 45.6 56.5 113.3 41.5 24.5 29.4 32.8 82.0 32.7 53.5 54.2 45.7 86.9 47.6 33.6 5.1 66.2 62.2 6.9 10.3 41.9 25.2 16.0 31.5 67.3 82.7 99.5 49.8 77.2 94.7 51.2 79.2 49.5 36.8 93.5 56.7 55.5 22.7 49.5 85.4 58.9 78.2 43.9 12.2 45.6 77.4 51.8 18.9 45.3 45.1 41.8 35.0 37.3 50.9 62.8 21.1 39.9 55.5 0.1 0.6 0.4 1.8 1.5 0.3 3.3 1.1 1.2 1.0 4.9 0.8 0.3 0.2 1.5 1.1 1.2 1.5 1.1 1.6 2.1 2.1 2.1 1.5 2.1 2.4 2.4 2.5 2.1 2.6 2.5 2.6 0.0 5.0 2.3 8.2 3.3 3.0 3.0 6.8 57.5 3.1 3.4 2.1 2.8 6.8 7.3 2.1 15.9 1.8 2.7 0.0 4.8 6.9 2.5 3.9 5.0 1.8 16.6 0.9 5.7 20.9 3.7 6.6 4.8 5.7 15.5 4.6 10.6 8.5 6.7 1.3 5.2 4.1 2.6 3.7 2.9 1.2 4.6 0.0 1.9 4.2 4.8 4.1 0.5 3.2 3.7 0.6 1.2 18.2 4.2 1.1 2.0 3.4 17.8 0.0 2.7 7.0 1.6 24.5 12.1 1.4 9.2 6.1 3.2 8.5 3.0 TIMM29 "C19orf52, TIM29" ENSG00000142444 "Translocase of inner mitochondrial membrane 29" Q9BSF4 19 10928811-10933535 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.0;Ductal cells: 21.6;Extravillous trophoblasts: 31.4;Hofbauer cells: 22.4;Proximal tubular cells: 22.1;Syncytiotrophoblasts: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041858 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "HPA041858: AB_10963429" "unprognostic (8.45e-2)" "prognostic favorable (9.93e-5)" "unprognostic (8.99e-2)" "unprognostic (5.21e-2)" "unprognostic (9.31e-2)" "unprognostic (8.10e-2)" "unprognostic (2.82e-3)" "unprognostic (1.42e-2)" "unprognostic (1.81e-1)" "unprognostic (5.92e-2)" "unprognostic (5.26e-3)" "unprognostic (1.80e-1)" "unprognostic (3.79e-3)" "prognostic favorable (7.03e-7)" "unprognostic (1.10e-1)" "unprognostic (2.35e-1)" "unprognostic (7.26e-3)" 8.4 11.7 4.6 5.4 4.5 10.1 8.4 3.7 6.1 10.4 3.5 11.0 8.0 11.0 1.1 14.9 9.0 3.1 13.5 4.9 3.8 11.5 12.2 8.1 6.0 5.8 4.3 7.9 9.9 3.3 10.7 4.6 4.2 10.1 2.0 1.1 10.1 3.8 23.5 13.9 9.7 2.1 3.8 10.7 11.0 13.0 4.2 5.3 7.5 5.9 2.8 10.5 11.4 4.7 21.3 8.0 6.2 10.4 5.3 5.1 16.7 14.3 7.6 10.7 9.9 14.7 7.0 18.0 24.7 7.0 5.8 20.1 3.3 8.9 1.8 21.3 25.0 20.7 8.4 10.0 8.4 15.8 15.5 4.5 8.6 7.5 3.2 4.3 6.5 15.7 23.1 15.4 4.1 19.0 17.4 29.1 21.8 6.6 34.0 23.4 8.7 22.3 4.7 8.6 15.6 15.8 16.9 9.1 18.3 2.3 13.1 16.7 10.7 17.1 10.0 21.6 23.1 49.7 52.8 19.8 10.6 19.3 14.8 3.7 8.7 9.8 5.3 9.3 8.9 17.9 10.6 11.7 5.8 15.0 10.1 8.3 1.7 11.3 7.4 11.0 12.8 3.8 4.6 4.5 3.7 6.1 4.9 3.8 5.8 4.3 4.2 3.8 4.2 4.7 6.9 3.2 5.8 0.0 3.5 0.0 0.0 0.0 0.0 0.0 9.6 8.4 0.0 0.0 1.3 16.5 0.0 36.0 13.8 0.0 19.6 21.6 0.0 9.6 10.9 4.9 0.0 0.0 0.0 10.5 31.4 5.2 0.0 9.2 1.3 10.5 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 2.4 0.0 0.0 22.1 0.7 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 35.7 5.5 14.7 0.0 0.0 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1235.1;Sertoli cells: 427.3;Syncytiotrophoblasts: 1946.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 322.7;CAPAN-2: 178.9;EFO-21: 403.6;HaCaT: 181.4;HBEC3-KT: 211.9;HUVEC TERT2: 173.4;TIME: 376.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" NA NA 370000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" 173.7 40.8 19.0 18.5 17.7 0.9 150.5 17.9 19.9 86.8 16.4 83.2 26.7 101.8 10.7 31.0 82.4 23.9 230.7 15.2 17.9 177.7 22.7 85.7 8.5 19.6 18.3 38.8 31.0 13.2 25.3 183.6 19.8 71.2 16.5 1.0 63.8 40.6 46.6 37.0 51.6 36.5 16.4 119.6 66.4 6.2 21.2 3.8 115.1 30.6 5.3 88.4 70.2 17.1 96.6 0.2 0.0 0.5 0.8 0.2 322.7 14.9 1.9 0.7 0.4 44.5 178.9 0.2 403.6 13.4 7.0 181.4 0.2 211.9 0.1 0.7 0.1 0.1 7.3 11.5 4.5 0.1 0.5 0.2 37.9 0.0 7.6 0.1 173.4 0.1 2.4 0.4 0.0 0.0 0.7 0.6 0.9 52.6 6.1 0.4 0.1 0.4 57.0 72.6 0.4 0.5 38.0 125.6 4.2 18.8 7.5 0.3 376.6 0.3 91.6 0.7 2.8 0.4 0.5 1.6 0.2 0.2 3.3 2.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.8 0.4 0.1 0.1 0.1 0.0 19.0 17.7 17.9 19.9 15.2 17.9 19.6 18.3 19.8 16.4 21.2 17.1 345.4 9.6 5.8 0.7 2.7 11.0 121.5 244.1 8.0 0.0 32.0 73.0 46.7 37.1 28.6 132.4 0.0 1235.1 2.6 158.9 1.9 378.7 1.4 8.4 3.2 161.4 11.4 13.5 0.1 92.2 223.5 35.0 50.0 14.4 14.7 49.7 306.6 4.4 89.3 0.0 1.1 35.5 14.2 8.8 10.3 0.7 7.5 4.2 23.2 13.1 2.0 0.2 0.0 0.5 0.0 344.6 115.3 4.1 0.2 131.4 45.2 80.9 9.1 0.4 427.3 9.5 357.4 0.3 0.8 4.9 6.5 1946.1 3.8 2.7 59.7 219.4 TINCR "FLJ90734, LINC00036, NCRNA00036, onco-lncRNA-16, PLAC2" ENSG00000223573 "TINCR ubiquitin domain containing" 19 5558167-5578349 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "skin 1: 119.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.4;Cytotrophoblasts: 61.0;Extravillous trophoblasts: 116.9;Squamous epithelial cells: 53.3;Suprabasal keratinocytes: 92.2;Syncytiotrophoblasts: 204.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 53.3;HaCaT: 35.9;MCF7: 14.9;SK-BR-3: 56.1" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (4.75e-2)" "unprognostic (2.99e-2)" "unprognostic (7.78e-2)" "unprognostic (1.78e-3)" "unprognostic (3.69e-1)" "unprognostic (2.54e-3)" "unprognostic (3.38e-2)" "unprognostic (3.95e-1)" "unprognostic (3.07e-1)" "unprognostic (1.66e-2)" "unprognostic (8.87e-2)" "unprognostic (1.24e-1)" "unprognostic (0.00e+0)" "unprognostic (4.22e-2)" "unprognostic (1.16e-1)" "unprognostic (3.63e-2)" "unprognostic (7.32e-2)" 0.9 1.9 6.6 0.7 6.6 2.9 3.6 4.7 8.0 5.7 1.0 2.0 0.5 0.6 1.5 21.2 0.7 0.5 0.5 4.9 4.8 1.1 0.1 2.9 0.9 4.1 7.3 0.6 0.3 0.3 2.9 17.8 7.2 4.7 2.5 2.8 4.3 0.8 0.9 119.1 0.8 0.4 0.6 0.9 0.3 1.7 11.7 0.2 0.5 0.0 4.9 1.4 13.7 4.4 2.0 1.6 0.2 0.6 0.5 1.0 53.3 0.2 0.1 0.1 0.2 0.9 6.3 0.3 0.5 0.2 0.5 35.9 0.6 0.1 0.4 0.6 1.2 0.4 1.9 0.5 0.1 0.7 0.5 0.0 11.5 0.3 0.3 0.3 0.0 2.9 0.3 0.8 0.1 14.9 0.2 0.8 1.0 1.4 2.5 1.2 0.4 1.3 0.0 3.8 0.7 0.1 3.9 56.1 5.6 5.0 6.7 0.5 0.0 0.6 0.5 1.0 0.1 1.4 0.4 1.0 0.3 0.7 1.1 3.2 0.4 0.5 0.4 0.3 0.3 0.9 0.3 0.3 0.1 0.9 0.3 0.4 2.3 0.6 0.4 1.3 0.4 0.2 6.6 6.6 4.7 8.0 4.9 4.8 4.1 7.3 7.2 0.6 11.7 4.4 2.1 12.8 1.7 0.3 0.6 46.4 5.2 2.9 21.1 4.2 6.1 3.2 1.3 4.3 2.6 1.8 0.0 61.0 1.4 3.3 11.7 0.0 0.4 1.2 1.8 2.4 1.8 0.0 0.8 0.5 116.9 1.7 0.0 2.6 0.0 0.5 2.9 0.3 6.6 0.0 1.2 3.0 4.1 1.4 4.6 0.2 0.6 1.2 7.2 0.0 0.5 3.5 1.0 0.0 0.2 0.1 7.5 0.7 0.1 5.9 0.1 0.4 1.9 2.1 0.0 3.6 1.3 1.0 3.1 53.3 92.2 204.5 1.1 0.2 0.9 10.1 TIPARP "ARTD14, DDF1, DKFZP434J214, DKFZp686N0351, PARP-1, PARP-7, PARP7, pART14, RM1" ENSG00000163659 "TCDD inducible poly(ADP-ribose) polymerase" Q7Z3E1 3 156673235-156706770 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 302.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 53.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 53.5" "Cell line enhanced" "Detected in all" "HBEC3-KT: 168.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036796 Approved Microtubules NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Microtubules "HPA036796: AB_10672268" "prognostic favorable (2.00e-5)" "unprognostic (3.50e-1)" "unprognostic (7.62e-2)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (4.56e-2)" "unprognostic (9.50e-2)" "unprognostic (3.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.43e-1)" "unprognostic (4.27e-3)" "unprognostic (2.01e-1)" "unprognostic (4.69e-2)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (4.90e-3)" 67.5 56.6 16.5 16.0 19.3 74.1 39.7 17.7 22.3 29.8 15.2 15.1 13.5 30.6 14.7 55.1 39.5 27.9 34.6 16.4 21.2 28.2 44.3 27.4 13.7 33.4 27.9 40.2 29.6 99.2 15.1 12.5 22.9 25.9 14.4 18.3 10.3 27.8 17.6 39.5 23.1 43.7 19.9 10.9 21.9 50.3 25.7 21.7 17.0 9.6 18.1 65.0 24.0 21.9 42.8 29.6 9.8 8.4 35.7 25.9 8.0 70.0 56.4 34.9 48.2 17.2 86.9 12.7 22.2 79.9 46.5 42.1 25.1 168.0 51.4 27.3 18.5 21.0 29.0 11.7 15.2 7.4 38.1 21.3 103.0 35.6 84.9 93.8 32.3 9.4 16.9 49.9 122.5 8.2 6.4 9.8 11.2 53.5 24.5 10.5 22.5 43.6 36.7 20.1 29.5 7.5 55.2 16.9 11.9 22.5 26.2 12.5 70.2 15.1 4.9 28.5 25.1 53.9 10.6 11.3 25.7 11.3 51.4 53.5 5.0 7.5 6.1 3.3 8.6 2.9 5.9 8.2 3.6 5.4 3.6 4.9 15.9 11.6 9.2 5.0 7.4 3.3 16.5 19.3 17.7 22.3 16.4 21.2 33.4 27.9 22.9 19.9 25.7 21.9 112.8 86.6 98.3 27.7 43.9 196.0 117.3 51.7 185.5 5.0 62.0 57.7 29.9 31.5 66.5 7.3 39.6 5.1 97.0 38.3 21.5 35.2 302.3 114.6 118.7 45.6 54.5 7.0 3.6 23.5 10.3 109.0 57.6 169.4 115.0 12.2 20.3 18.9 19.2 21.9 8.7 32.4 18.3 18.5 97.5 28.0 19.6 101.7 37.4 12.2 17.3 10.1 16.5 22.1 20.4 36.9 40.1 19.2 60.5 83.9 40.4 16.2 43.5 10.4 13.1 138.0 87.7 58.0 33.4 100.1 121.5 7.5 105.4 7.3 18.2 187.8 TK1 ENSG00000167900 "Thymidine kinase 1" P04183 17 78174091-78187233 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA synthesis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 92.8;Erythroid cells: 108.6;Extravillous trophoblasts: 210.4;Hofbauer cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 34.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enhanced" "Detected in some" "white matter: 3.6" "Low region specificity" "Detected in many" CAB004683 Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB004683: AB_437067" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.14e-3)" "unprognostic (3.22e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (6.87e-4)" "prognostic unfavorable (3.03e-5)" "unprognostic (4.05e-2)" "unprognostic (3.18e-3)" "unprognostic (6.64e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (6.50e-11)" "unprognostic (5.55e-3)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (4.94e-2)" 3.7 2.7 2.5 20.4 3.4 77.9 5.9 3.6 3.4 5.9 1.3 24.4 18.0 3.0 0.2 27.2 4.9 3.4 2.8 2.7 2.4 11.0 9.2 9.1 34.8 3.4 3.3 1.3 5.6 0.6 0.6 14.8 3.3 3.4 15.7 0.1 6.3 1.5 5.5 14.2 18.3 10.1 2.6 12.4 17.9 3.1 3.8 25.1 2.0 1.6 30.6 5.5 9.0 4.4 443.9 357.7 68.2 92.5 7.6 28.0 47.3 207.6 113.2 323.1 442.3 324.2 178.7 144.1 72.9 131.7 133.9 204.2 63.4 187.1 158.0 51.2 230.4 252.5 119.9 213.3 2.2 107.1 162.9 13.8 7.1 166.1 22.5 22.3 137.9 49.4 156.7 311.9 130.8 352.0 56.0 68.6 36.7 259.1 240.9 152.6 276.4 324.1 90.6 138.5 33.6 94.2 162.0 481.2 59.7 59.4 303.9 156.1 57.8 302.3 305.7 219.9 292.1 132.5 71.4 181.9 149.0 71.9 142.1 0.0 1.1 0.0 1.8 2.1 0.7 5.8 7.9 4.0 3.4 1.7 0.4 2.2 1.8 10.8 1.7 1.1 34.0 5.5 2.5 3.4 3.6 3.4 2.7 2.4 3.4 3.3 3.3 2.6 3.8 4.4 1.6 0.0 2.7 0.0 17.1 28.4 13.3 17.8 2.2 0.0 10.6 9.4 0.9 2.8 8.3 12.9 0.0 92.8 3.6 35.0 7.9 7.7 3.0 9.2 3.3 10.6 5.4 108.6 0.3 11.2 210.4 15.7 19.4 7.0 0.0 15.9 7.5 10.5 65.2 0.0 0.2 32.7 8.2 15.5 19.1 6.8 0.6 10.9 3.6 0.0 5.7 0.0 3.1 0.0 1.0 9.6 7.5 0.7 53.6 4.9 3.1 17.5 5.8 0.0 0.0 1.7 20.1 3.8 16.8 24.7 11.2 51.0 8.7 1.7 60.8 24.0 TKT ENSG00000163931 Transketolase P29401 3 53224712-53256052 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 667.0" "Cell type enhanced" "Detected in all" "Kupffer cells: 696.7;monocytes: 624.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 447.9;eosinophil: 274.4;intermediate monocyte: 199.0;myeloid DC: 203.8;neutrophil: 375.3;non-classical monocyte: 242.6" "Group enriched" "Detected in all" 9 "dendritic cells: 203.8;granulocytes: 375.3;monocytes: 447.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029480, HPA029481" Enhanced Enhanced Nucleoplasm NA NA 150000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA029480: AB_10599307, HPA029481: AB_10601895" "unprognostic (5.05e-2)" "unprognostic (3.34e-2)" "unprognostic (1.02e-2)" "unprognostic (1.77e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "prognostic unfavorable (7.21e-6)" "unprognostic (6.78e-2)" "unprognostic (1.70e-1)" "unprognostic (4.73e-2)" "unprognostic (3.06e-3)" "unprognostic (1.36e-2)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "unprognostic (1.07e-1)" "unprognostic (3.29e-1)" "unprognostic (9.90e-3)" 152.2 93.2 78.0 66.2 80.0 667.0 71.9 93.2 82.3 59.7 60.5 73.2 84.2 44.7 19.2 168.5 53.7 97.2 27.4 72.3 96.9 68.2 58.1 93.4 69.2 89.2 89.9 87.7 154.0 41.4 45.6 61.2 93.8 48.8 48.8 21.7 54.9 50.9 12.8 47.0 58.1 51.6 77.4 99.8 66.1 20.2 87.9 82.9 116.1 15.2 67.4 130.9 85.5 97.2 313.0 1542.9 216.0 241.5 470.8 570.8 439.5 206.2 353.8 348.8 330.8 430.1 779.3 388.5 96.8 302.9 673.3 438.3 377.9 775.8 102.4 131.0 210.3 259.6 1022.2 655.2 573.9 321.4 168.1 416.0 437.5 418.5 213.7 949.2 444.9 323.8 188.3 164.7 144.5 381.6 338.6 358.1 737.1 603.0 367.9 201.1 98.5 726.2 550.3 520.2 139.6 103.7 383.4 605.3 365.1 656.7 188.8 437.4 335.9 107.2 164.2 320.0 401.9 94.5 190.3 235.7 234.4 321.0 203.8 51.5 447.9 274.4 17.8 199.0 22.8 39.7 25.8 20.6 203.8 21.1 26.6 20.7 375.3 30.8 242.6 34.4 36.7 312.4 78.0 80.0 93.2 82.3 72.3 96.9 89.2 89.9 93.8 77.4 87.9 97.2 79.5 134.6 125.6 46.7 92.1 79.4 384.6 325.3 287.4 41.0 99.3 80.5 14.9 75.8 149.5 62.5 29.2 349.0 69.7 139.1 80.3 197.7 6.5 87.4 79.6 81.8 52.6 150.3 16.9 269.8 249.8 80.2 168.7 95.5 62.7 123.6 75.0 83.4 256.0 37.0 23.9 149.6 142.4 696.7 110.5 8.9 157.2 333.3 76.5 17.8 624.4 88.8 46.4 17.1 39.3 193.6 81.4 106.8 109.4 337.7 141.5 219.1 99.2 46.3 52.6 35.9 102.1 16.8 30.6 409.3 67.1 413.6 78.8 427.2 276.7 413.6 TLCD1 ENSG00000160606 "TLC domain containing 1" Q96CP7 17 28724348-28727935 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 36.4;Syncytiotrophoblasts: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "plasmacytoid DC: 21.7" "Lineage enriched" "Detected in many" 11 "dendritic cells: 21.7" "Cell line enhanced" "Detected in many" "SK-BR-3: 116.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042366 Enhanced NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA042366: AB_10794419" "unprognostic (1.23e-1)" "unprognostic (3.78e-2)" "unprognostic (8.52e-2)" "unprognostic (3.74e-2)" "unprognostic (1.42e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.82e-1)" "unprognostic (1.04e-1)" "unprognostic (4.47e-3)" "unprognostic (9.96e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (9.05e-5)" "unprognostic (1.56e-1)" "unprognostic (7.56e-2)" "unprognostic (1.86e-2)" "unprognostic (3.93e-2)" 2.6 5.4 14.5 3.2 14.9 1.4 5.2 16.6 21.5 4.4 13.1 8.1 8.1 1.8 13.8 13.1 14.5 2.3 2.3 14.7 14.9 25.9 15.0 7.4 3.2 14.7 15.7 1.1 11.9 3.4 3.9 4.5 14.1 6.5 8.2 1.6 12.9 3.7 0.8 20.6 4.0 1.0 14.7 1.3 8.8 13.1 15.1 4.5 5.3 0.1 9.8 13.8 5.7 13.9 12.4 55.8 14.9 12.7 10.2 18.5 34.6 10.1 17.8 4.7 6.7 31.1 21.3 3.9 15.3 12.1 21.4 19.4 16.6 31.6 7.2 3.1 15.8 6.6 33.4 38.2 10.9 14.0 1.0 12.5 25.4 17.1 30.0 7.3 4.1 1.2 24.3 0.6 8.1 43.5 1.6 5.9 17.0 42.4 10.0 4.6 6.3 23.7 38.9 22.2 28.1 5.6 20.6 116.2 11.3 22.1 57.1 4.9 4.2 4.8 16.2 8.9 16.4 4.0 4.9 9.0 9.1 8.0 16.2 1.9 0.9 0.2 0.2 1.1 0.5 1.4 0.5 0.3 0.9 0.6 0.2 0.3 0.6 0.4 0.7 21.7 0.4 0.4 14.5 14.9 16.6 21.5 14.7 14.9 14.7 15.7 14.1 14.7 15.1 13.9 2.1 0.0 8.4 4.2 2.5 2.4 11.8 23.9 2.2 0.2 19.0 17.1 0.9 7.2 16.6 12.9 0.0 18.3 1.0 7.8 0.0 9.0 17.0 24.1 4.6 1.7 4.8 1.3 0.0 8.3 36.4 4.2 7.1 23.6 0.0 0.9 1.1 18.6 3.5 1.7 0.0 8.8 14.2 0.8 3.7 15.6 1.2 1.5 3.6 0.0 2.1 5.3 0.0 1.0 0.0 10.5 4.5 0.4 1.8 23.7 8.5 6.9 31.0 0.7 0.0 2.0 8.8 20.2 7.2 8.4 2.0 32.3 2.2 3.0 8.0 23.1 TLCD2 ENSG00000185561 "TLC domain containing 2" A6NGC4 17 1702816-1710377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 112.4;Proximal enterocytes: 68.9;Skeletal myocytes: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 3.4;neutrophil: 1.6" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.0;HaCaT: 8.4;SiHa: 11.2;T-47d: 9.4" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 14.2" HPA046063 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA046063: AB_2679520" "unprognostic (1.78e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (4.04e-2)" "unprognostic (7.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.36e-5)" "unprognostic (3.77e-2)" "unprognostic (2.82e-1)" "unprognostic (7.79e-2)" "unprognostic (4.44e-2)" 10.3 9.4 0.6 1.8 0.7 2.1 4.7 1.6 0.9 3.0 2.3 7.3 6.0 1.8 1.2 4.7 2.7 1.8 2.1 0.6 0.5 1.8 7.0 3.9 0.7 1.0 0.7 2.5 1.2 1.0 1.1 1.5 1.0 1.9 5.3 10.5 2.9 0.9 1.7 2.4 6.9 1.2 0.7 1.3 4.7 0.6 1.0 0.1 1.6 0.8 0.8 3.1 3.5 1.6 1.0 1.1 1.1 3.5 8.1 9.0 0.3 1.9 1.8 1.0 0.7 6.9 3.1 0.1 1.9 3.1 1.0 8.4 1.5 0.9 0.7 0.2 0.7 0.9 2.4 0.3 2.3 0.1 2.4 7.6 3.2 1.2 2.2 2.9 0.7 0.1 0.8 0.4 0.9 1.9 0.1 0.4 0.1 3.4 0.6 0.1 5.3 0.2 0.7 2.7 0.2 0.4 11.2 1.0 1.6 1.5 9.4 0.8 2.6 0.5 2.3 2.1 0.5 0.1 0.1 0.1 0.6 0.3 1.0 3.4 0.2 0.4 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.4 0.2 0.2 1.6 0.3 0.1 0.2 0.1 0.1 0.6 0.7 1.6 0.9 0.6 0.5 1.0 0.7 1.0 0.7 1.0 1.6 19.0 51.3 55.5 0.3 1.6 0.0 8.2 0.0 4.0 7.9 5.8 9.5 2.7 17.2 18.0 11.0 129.3 4.9 2.0 112.4 0.0 7.3 1.1 12.9 10.4 14.1 9.0 11.2 0.5 9.6 2.6 14.9 20.9 13.3 15.8 3.9 18.9 24.2 5.5 0.0 0.4 24.6 0.0 6.5 0.0 1.8 13.4 10.7 0.0 3.7 1.4 11.7 0.0 0.0 0.1 13.5 40.1 5.7 3.3 6.3 68.9 1.1 19.9 57.8 6.6 124.2 17.8 0.6 0.8 9.1 0.3 4.0 5.1 5.4 35.7 13.0 TLCD3A "CT120, FAM57A, FLJ22282" ENSG00000167695 "TLC domain containing 3A" Q8TBR7 17 732412-742968 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 71.7" "Group enriched" "Detected in some" 5 "Extravillous trophoblasts: 20.1;Hofbauer cells: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.46e-1)" "unprognostic (6.16e-2)" "unprognostic (5.64e-2)" "prognostic favorable (3.53e-6)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (1.32e-3)" "unprognostic (2.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.59e-2)" "unprognostic (9.40e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (4.88e-2)" "unprognostic (1.60e-1)" "unprognostic (8.05e-2)" "unprognostic (1.39e-2)" 7.7 3.5 4.5 6.1 4.9 2.4 8.2 9.7 5.8 10.2 9.5 10.7 12.5 7.3 2.6 23.6 7.1 12.3 4.9 4.7 5.7 5.7 3.7 7.1 3.2 4.2 4.6 7.4 9.7 6.1 8.3 8.2 4.9 9.6 10.0 3.8 11.6 10.9 2.8 71.7 8.6 8.5 4.5 2.9 18.4 12.1 5.5 4.7 8.0 2.9 9.2 18.5 15.9 5.2 63.8 39.4 27.5 36.6 35.5 47.1 27.3 53.9 46.1 53.2 59.4 19.2 9.8 14.4 28.3 51.7 17.1 61.3 57.3 44.3 58.9 38.3 53.1 14.8 26.8 46.6 28.1 12.4 20.7 39.6 38.8 24.2 63.5 24.5 37.3 19.6 13.6 1.7 31.2 22.1 5.3 3.7 12.2 40.7 13.7 25.6 10.8 1.4 38.1 48.9 13.2 25.0 25.7 2.5 16.7 18.0 10.3 13.7 29.1 51.9 23.6 60.8 65.3 4.6 13.3 15.2 47.2 23.9 32.1 0.0 0.0 0.0 1.2 0.0 1.1 0.1 0.2 0.5 0.1 0.5 0.0 0.3 0.0 0.0 0.0 0.1 1.5 0.1 4.5 4.9 9.7 5.8 4.7 5.7 4.2 4.6 4.9 4.5 5.5 5.2 2.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 20.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 TLCD4 "FLJ31842, TMEM56" ENSG00000152078 "TLC domain containing 4" Q96MV1 1 95117355-95197607 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 130.0" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 77.9" "Cancer enhanced" "Detected in many" "liver cancer: 13.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 22.4;RH-30: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046762 Approved "Nuclear speckles" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA046762: AB_2679792" "unprognostic (1.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.98e-3)" "unprognostic (2.79e-1)" "unprognostic (3.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.82e-3)" "unprognostic (3.63e-2)" "unprognostic (4.42e-3)" "unprognostic (2.69e-2)" "unprognostic (4.99e-2)" "unprognostic (4.40e-2)" "unprognostic (1.16e-3)" "unprognostic (1.10e-1)" "unprognostic (9.46e-2)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" 5.3 9.9 9.4 2.1 10.6 20.5 2.6 19.5 15.1 2.4 0.0 13.6 5.5 3.4 2.5 2.3 2.4 4.2 25.7 10.6 6.3 5.7 130.0 3.7 0.4 4.9 5.7 1.7 7.4 6.4 3.4 4.4 4.2 5.3 10.2 3.1 8.3 2.9 13.0 1.6 8.5 3.6 6.9 0.7 5.0 4.8 9.9 0.3 7.3 9.7 0.5 4.7 1.3 12.6 22.4 12.6 1.7 2.6 0.8 0.0 2.9 0.8 0.5 2.8 6.5 9.1 10.4 0.0 10.7 0.4 20.0 0.2 7.4 1.1 4.8 15.5 4.1 0.5 9.2 2.0 0.8 0.4 0.6 1.2 0.4 2.1 0.0 4.4 0.0 1.2 19.8 1.2 0.6 1.9 1.3 0.1 1.7 0.7 6.9 0.0 35.7 0.6 12.0 14.4 4.5 3.6 15.6 10.8 6.7 1.8 11.7 0.4 0.2 0.3 9.0 1.1 7.9 3.8 8.0 0.0 1.5 0.1 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.4 10.6 19.5 15.1 10.6 6.3 4.9 5.7 4.2 6.9 9.9 12.6 5.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.9 0.0 0.0 0.0 0.0 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.5 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 TLR8 CD288 ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.7;lymphoid tissue: 16.8" "Group enriched" "Detected in some" 6 "Kupffer cells: 49.8;Macrophages: 21.1;monocytes: 39.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 74 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 78 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001608 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" 3.6 0.5 0.2 16.8 0.2 5.7 0.9 0.2 0.3 0.7 0.5 1.7 0.8 0.4 0.1 0.9 0.6 2.5 0.8 0.1 0.3 0.5 2.2 10.7 6.1 1.1 0.7 0.4 0.6 0.3 0.1 4.3 0.8 0.3 1.8 0.0 0.3 0.2 0.2 0.2 1.5 3.8 0.5 13.3 0.8 0.4 0.4 1.7 0.4 1.3 1.9 3.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 14.9 0.0 0.2 0.0 0.0 8.4 0.0 0.0 0.0 27.6 0.0 15.6 0.0 0.0 3.8 0.2 0.2 0.2 0.3 0.1 0.3 1.1 0.7 0.8 0.5 0.4 0.9 0.0 0.0 3.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.7 5.3 0.0 0.0 0.0 0.0 49.8 5.1 0.0 0.0 21.1 0.0 0.0 39.7 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TM4SF1 "L6, M3S1" ENSG00000169908 "Transmembrane 4 L six family member 1" P30408 3 149369022-149377692 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 5463.1;Endothelial cells: 1843.0;Pancreatic endocrine cells: 2557.3;Prostatic glandular cells: 2717.0;Urothelial cells: 4902.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 703.8;hTERT-RPE1: 925.5;HUVEC TERT2: 633.3;LHCN-M2: 687.7;OE19: 672.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002760, HPA002823" Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB002760: , HPA002823: AB_1079221" "unprognostic (1.94e-1)" "unprognostic (2.25e-2)" "unprognostic (5.20e-2)" "unprognostic (4.79e-2)" "unprognostic (2.89e-2)" "unprognostic (2.47e-3)" "unprognostic (3.85e-3)" "unprognostic (2.74e-2)" "unprognostic (5.09e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.06e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (4.67e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.43e-6)" 365.9 71.3 41.9 50.5 43.1 2.6 192.8 44.1 68.2 82.6 65.6 61.6 38.3 74.9 58.2 210.9 74.7 237.6 181.7 42.2 45.2 155.1 92.6 229.8 25.2 45.1 43.9 49.7 211.7 19.9 20.2 194.6 47.7 79.9 59.9 6.0 180.9 32.0 50.2 63.5 62.2 94.6 45.4 120.5 129.7 19.5 53.5 17.0 72.5 64.2 60.2 150.9 115.5 45.9 367.9 401.9 0.0 1.0 108.4 422.2 0.6 115.2 455.5 23.9 8.8 159.7 703.8 0.1 351.3 23.5 545.5 434.0 1.9 80.0 22.9 0.9 0.0 3.9 391.8 521.8 39.4 0.0 0.5 40.0 19.1 169.7 81.5 925.5 633.3 0.0 0.3 0.8 687.7 0.5 0.0 0.7 1.5 672.9 170.7 0.2 0.9 0.8 449.3 54.8 0.2 0.5 46.8 25.1 4.4 6.0 0.8 1.7 404.7 233.6 38.9 4.8 244.3 0.5 0.7 1.1 337.4 0.4 62.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.9 43.1 44.1 68.2 42.2 45.2 45.1 43.9 47.7 45.4 53.5 45.9 1131.0 576.9 342.3 0.3 7.5 278.0 5463.1 668.3 272.6 0.1 956.5 363.1 24.0 274.5 984.3 57.0 0.0 0.8 17.0 176.6 0.0 1383.5 5.2 514.1 168.0 1843.0 39.2 15.6 0.0 1600.9 0.9 297.2 147.8 1807.5 31.5 0.2 1263.6 21.8 1.9 0.0 0.0 15.9 382.5 27.8 222.1 11.3 255.7 35.6 300.6 30.9 26.4 0.0 0.0 0.0 0.3 2557.3 251.8 176.0 11.1 2717.0 0.3 1.2 238.5 0.0 322.1 37.7 311.0 6.6 1.4 925.8 253.7 1.4 44.1 44.2 46.6 4902.9 TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 246.0" "Cell type enhanced" "Detected in all" "Granulosa cells: 482.7;Hepatocytes: 220.6;Muller glia cells: 204.7;Theca cells: 204.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 38.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 69.2;RPTEC TERT1: 86.2;T-47d: 143.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA030691: AB_10602480, HPA072704: AB_2686551" "unprognostic (1.62e-1)" "unprognostic (5.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (6.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "unprognostic (1.69e-1)" "prognostic favorable (8.49e-8)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.44e-2)" 63.4 246.0 27.8 2.6 28.5 4.1 29.1 32.8 33.9 17.4 64.1 7.8 9.4 3.4 17.0 39.6 12.8 7.0 47.3 30.0 29.7 18.9 86.4 10.1 3.4 34.0 32.0 36.5 69.9 36.3 19.5 3.9 32.5 41.1 3.9 6.0 46.9 6.0 7.1 68.2 8.3 1.9 30.1 5.1 35.6 11.5 32.6 5.6 15.5 3.7 8.4 5.5 22.1 35.1 7.7 10.9 27.3 35.1 8.1 1.3 15.4 1.8 4.5 2.7 3.0 26.0 35.8 16.3 26.9 2.2 1.0 13.3 11.6 21.2 1.9 16.7 5.0 10.2 2.7 54.5 18.8 4.2 10.6 3.7 5.0 14.6 3.9 12.6 3.9 28.7 5.8 13.9 0.8 69.2 8.3 18.6 12.6 18.4 11.2 22.4 1.2 39.9 86.2 12.6 27.2 30.5 1.2 28.2 6.1 19.5 143.9 11.4 3.1 0.4 3.4 3.8 2.3 27.1 18.1 8.4 2.5 5.9 1.0 1.1 1.6 3.4 9.1 1.5 7.0 12.4 5.6 7.8 1.5 11.9 11.8 9.0 1.1 12.5 0.9 38.1 5.6 4.9 27.8 28.5 32.8 33.9 30.0 29.7 34.0 32.0 32.5 30.1 32.6 35.1 4.0 9.6 43.7 23.5 12.7 1.9 6.2 33.6 5.7 19.2 52.2 38.5 99.4 52.9 36.6 44.1 10.4 72.9 16.3 23.3 17.6 27.1 28.8 17.9 2.6 5.7 59.4 13.7 11.6 27.7 4.6 4.3 31.1 16.5 7.0 482.7 5.0 220.6 15.6 25.2 15.3 21.8 52.9 6.3 2.7 59.3 9.9 5.8 12.4 2.8 9.4 204.7 7.2 17.1 36.5 21.7 23.7 2.2 12.9 31.3 29.0 77.5 37.9 23.6 13.1 1.6 21.8 13.3 17.9 18.0 7.0 82.1 8.3 204.8 19.0 10.4 TM9SF4 "dJ836N17.2, KIAA0255" ENSG00000101337 "Transmembrane 9 superfamily member 4" Q92544 20 32109714-32167258 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064099 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA064099: AB_2685190" "unprognostic (3.10e-2)" "unprognostic (9.03e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.37e-6)" "unprognostic (3.85e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (1.37e-1)" "unprognostic (3.23e-3)" "unprognostic (1.91e-1)" "unprognostic (6.65e-2)" "unprognostic (7.68e-2)" "unprognostic (6.98e-3)" "unprognostic (7.66e-2)" "unprognostic (1.45e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" 23.4 21.1 16.7 23.4 16.9 16.3 22.6 14.8 19.5 26.5 20.7 32.1 29.6 25.0 30.4 30.3 34.8 22.1 24.4 17.6 17.9 26.6 33.7 24.4 18.9 15.3 15.8 28.7 30.5 52.6 17.0 39.6 16.3 28.0 37.2 17.7 30.7 26.8 23.3 32.0 29.0 31.8 14.0 23.6 29.8 18.0 18.9 21.0 24.7 24.3 24.2 27.9 22.9 16.2 59.0 41.1 46.1 53.2 88.7 71.9 59.1 47.8 71.9 65.6 63.7 122.2 71.1 41.0 88.2 78.2 102.4 94.8 52.4 101.9 56.4 23.5 29.4 94.4 34.6 93.1 78.3 45.9 52.0 76.2 76.3 49.7 79.6 80.3 59.1 48.3 60.4 74.5 51.8 62.5 46.5 36.4 41.2 71.2 50.0 43.9 65.1 51.4 57.2 41.3 39.0 45.7 88.6 57.7 51.4 61.0 72.4 52.0 48.5 119.2 36.7 63.7 59.1 74.9 65.9 38.2 94.4 149.6 54.6 24.0 48.4 9.9 20.0 50.5 24.8 16.5 17.7 22.9 41.8 13.1 19.4 16.4 11.7 18.8 67.8 13.7 19.1 34.6 16.7 16.9 14.8 19.5 17.6 17.9 15.3 15.8 16.3 14.0 18.9 16.2 16.4 25.6 25.2 33.0 16.2 7.0 17.4 27.1 17.6 12.2 15.7 16.1 16.0 14.3 36.5 9.2 16.7 29.4 11.9 25.2 1.9 19.0 53.5 18.0 25.2 18.4 13.9 12.4 31.2 18.5 21.7 20.4 23.4 24.9 8.2 19.3 16.8 26.2 24.0 8.4 37.1 31.7 20.3 19.1 10.5 57.5 16.8 22.5 7.2 24.4 25.2 14.0 10.3 28.6 34.8 19.8 25.7 10.9 23.1 22.1 29.8 14.0 32.8 12.3 6.6 19.9 25.8 26.5 9.7 21.8 11.4 37.6 16.8 23.4 27.5 21.9 TMC4 ENSG00000167608 "Transmembrane channel like 4" 19 54160108-54173250 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 45.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 160.1;Paneth cells: 119.7;Proximal enterocytes: 228.6;Respiratory ciliated cells: 155.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "OE19: 17.3;T-47d: 30.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA048635 Approved Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA048635: AB_2680470" "unprognostic (7.55e-2)" "unprognostic (1.66e-1)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.82e-2)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-3)" "unprognostic (7.59e-2)" "unprognostic (3.09e-1)" "prognostic favorable (1.54e-8)" "unprognostic (6.70e-2)" "unprognostic (2.48e-1)" "unprognostic (8.94e-2)" "unprognostic (1.79e-2)" 2.3 0.4 0.2 0.4 0.2 0.0 12.5 0.3 0.7 8.7 0.0 38.6 33.1 3.2 0.0 14.8 16.8 8.4 5.7 0.3 0.2 25.5 2.6 11.9 0.1 0.5 0.8 1.1 45.6 4.5 21.0 0.7 0.7 21.6 12.0 0.0 42.1 4.9 1.4 5.4 37.2 0.4 0.2 0.2 31.9 0.5 0.2 0.0 31.3 0.1 0.5 18.9 9.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 17.3 0.0 0.1 0.0 0.7 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.7 0.3 0.2 0.5 0.8 0.7 0.2 0.2 0.1 1.5 28.9 30.0 0.7 1.5 2.4 26.9 78.6 24.5 0.3 42.5 19.8 1.7 51.5 94.4 46.0 0.0 22.7 3.7 160.1 13.7 78.2 0.0 59.7 6.6 2.2 41.6 0.0 0.6 64.1 6.1 1.8 102.4 56.2 5.7 0.5 1.1 0.6 3.9 0.0 0.6 92.7 57.0 1.3 3.0 0.1 1.2 3.2 1.8 0.0 2.1 0.1 4.1 1.0 0.7 50.7 119.7 0.7 2.4 22.0 228.6 29.0 155.7 0.5 26.3 0.9 13.6 0.4 1.9 22.0 1.7 23.4 2.8 2.1 77.1 43.1 TMC6 "EVER1, EVIN1, LAK-4P, TNRC6C-AS1" ENSG00000141524 "Transmembrane channel like 6" Q7Z403 17 78107397-78132407 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 110.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 108.7;SK-BR-3: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051430 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA051430: AB_2681483" "unprognostic (6.34e-2)" "unprognostic (5.14e-2)" "unprognostic (5.55e-2)" "unprognostic (2.81e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" "unprognostic (5.36e-2)" "unprognostic (6.27e-2)" "unprognostic (1.47e-1)" "unprognostic (9.94e-2)" "unprognostic (1.74e-1)" "unprognostic (6.61e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.82e-4)" "unprognostic (2.70e-2)" "unprognostic (1.10e-2)" "prognostic favorable (3.20e-4)" 29.5 6.8 19.2 45.4 50.5 72.7 25.2 43.4 33.5 11.3 5.2 23.5 21.7 7.6 1.0 25.4 14.1 9.7 35.9 19.3 26.4 20.6 9.1 40.3 69.7 59.3 49.7 3.8 14.6 3.1 5.6 8.8 55.9 20.2 6.6 0.6 29.3 7.9 3.5 17.9 50.6 3.5 35.8 110.5 14.6 2.6 48.4 26.3 12.9 1.8 32.4 14.6 18.4 81.9 17.9 14.0 7.5 6.0 0.0 0.0 15.2 0.0 0.0 0.2 0.2 25.2 19.2 19.7 23.7 0.0 6.3 31.0 1.0 5.9 0.0 2.0 11.3 41.3 4.2 31.0 1.9 38.3 67.0 1.1 16.2 0.0 1.3 0.2 14.7 9.2 108.7 73.3 0.0 36.1 18.9 65.4 5.9 32.9 4.9 8.4 0.6 58.9 11.4 65.1 1.9 4.9 5.7 121.0 33.2 9.7 68.7 57.6 5.2 0.0 8.7 0.1 0.3 57.6 27.3 13.2 0.0 60.4 1.0 17.7 11.6 23.2 56.2 38.3 49.0 28.5 41.7 46.2 18.6 21.7 36.5 39.6 15.3 35.8 63.5 5.7 38.0 33.5 19.2 50.5 43.4 33.5 19.3 26.4 59.3 49.7 55.9 35.8 48.4 81.9 43.8 41.7 29.6 8.1 69.5 11.1 21.0 22.3 7.4 3.2 17.4 6.5 14.7 10.0 41.5 16.5 0.0 1.2 79.8 25.0 0.0 41.2 0.3 5.1 1.6 19.7 9.1 28.4 0.2 23.1 26.4 4.6 10.2 8.0 40.5 0.7 23.6 2.2 67.0 1.7 0.2 14.0 40.7 66.2 29.9 1.2 9.6 44.7 14.2 20.6 62.0 7.5 85.5 1.5 50.8 40.5 53.7 1.2 62.6 31.5 20.3 2.0 20.3 1.8 13.1 4.6 13.5 0.5 2.2 8.4 10.2 3.7 83.7 2.5 30.3 37.4 TMC7 FLJ21240 ENSG00000170537 "Transmembrane channel like 7" Q7Z402 16 18983934-19063942 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;testis: 9.6" "Group enriched" "Detected in many" 6 "Early spermatids: 172.0;Late spermatids: 44.6;Oligodendrocytes: 96.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029465 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA029465: AB_10600914" "unprognostic (1.80e-4)" "unprognostic (6.13e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.25e-1)" "unprognostic (1.19e-3)" "unprognostic (7.60e-5)" "prognostic unfavorable (3.20e-4)" "unprognostic (7.60e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.64e-4)" "unprognostic (3.39e-1)" "unprognostic (1.00e-1)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (5.66e-2)" "prognostic favorable (9.20e-4)" 2.1 0.2 6.0 1.0 15.8 0.3 1.7 12.4 10.6 0.5 0.4 3.8 2.5 0.7 0.6 0.4 0.4 1.4 1.4 7.0 9.0 0.6 0.3 2.9 0.3 13.8 13.2 0.2 0.4 0.4 0.3 4.3 12.6 1.5 4.5 1.1 0.4 0.9 0.9 1.1 2.7 1.1 7.5 0.6 3.1 9.6 15.0 0.2 0.8 0.9 0.2 8.1 0.8 23.9 1.9 3.5 1.0 1.9 0.2 1.6 4.8 0.6 1.0 0.7 1.5 1.2 8.5 0.2 7.9 0.7 1.8 6.8 2.9 2.8 0.9 0.1 2.0 0.1 3.6 5.5 0.2 0.2 0.1 0.3 4.1 6.5 7.2 2.2 2.6 3.8 2.2 0.2 2.8 3.9 0.3 0.3 3.1 11.1 5.1 0.2 3.1 0.2 1.3 8.7 0.6 1.9 2.1 5.4 0.6 4.9 1.7 0.6 2.3 1.1 1.8 1.3 3.3 0.4 0.9 0.2 5.4 0.3 1.0 0.7 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.0 6.0 15.8 12.4 10.6 7.0 9.0 13.8 13.2 12.6 7.5 15.0 23.9 12.6 3.2 6.2 3.9 0.1 0.4 4.4 3.2 0.0 0.6 1.3 0.4 0.7 1.5 2.0 0.0 0.0 0.2 0.0 13.4 0.0 4.1 172.0 1.4 0.4 4.9 1.2 2.7 7.5 11.0 2.3 0.6 9.2 2.4 0.0 1.2 4.6 0.2 0.2 0.0 12.1 6.0 4.1 0.0 1.2 44.6 1.2 0.6 0.0 6.5 0.2 0.3 2.1 6.6 96.5 14.0 8.0 0.4 0.1 2.3 3.6 0.3 0.9 2.7 0.0 1.6 2.2 6.9 12.1 1.9 1.0 0.3 0.4 0.1 7.6 17.3 TMEM100 "FLJ10970, FLJ37856" ENSG00000166292 "Transmembrane protein 100" Q9NV29 17 55719627-55732121 "Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 192.5" "Cell type enhanced" "Detected in some" "Adipocytes: 57.8;Endothelial cells: 25.5;Fibroblasts: 40.7;Leydig cells: 40.7;Peritubular cells: 52.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 28.9;ASC TERT1: 19.5;HHSteC: 44.8;HSkMC: 20.6;U-87 MG: 13.9;WM-115: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055936 Approved Uncertain Nucleoplasm NA NA "Cluster 19: Lung - Lung function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA055936: AB_2682975" "unprognostic (1.35e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (4.02e-2)" "unprognostic (6.78e-3)" "unprognostic (3.07e-1)" "prognostic favorable (2.67e-5)" "unprognostic (5.74e-2)" "unprognostic (1.87e-2)" "unprognostic (4.66e-1)" "unprognostic (1.89e-2)" "unprognostic (8.11e-3)" "prognostic unfavorable (1.32e-4)" "unprognostic (4.91e-3)" "unprognostic (1.12e-1)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" 40.8 5.0 5.4 3.2 5.5 0.0 27.6 4.3 9.0 15.8 6.0 14.5 6.7 3.6 36.6 6.5 8.0 7.3 18.7 5.1 7.0 1.9 7.0 192.5 1.2 5.5 7.0 26.5 2.3 0.8 11.2 54.1 6.0 10.3 11.6 0.4 8.0 24.7 9.7 4.6 13.2 5.5 4.6 6.9 30.2 2.7 8.1 1.1 7.5 14.1 0.6 11.1 8.2 4.7 0.0 0.0 5.9 0.0 28.9 19.5 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 44.8 0.0 0.0 20.6 0.0 1.4 0.1 0.2 0.0 0.3 1.0 0.1 0.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 8.7 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.3 1.9 3.9 0.0 0.8 0.0 0.1 13.9 0.1 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.5 4.3 9.0 5.1 7.0 5.5 7.0 6.0 4.6 8.1 4.7 57.8 0.0 3.6 2.3 0.1 2.5 0.3 0.0 1.2 0.7 0.4 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.1 4.0 25.5 0.0 0.0 0.1 0.0 0.0 40.7 1.5 0.2 1.3 0.1 7.1 15.2 0.1 0.0 1.6 0.0 0.0 0.0 4.9 0.5 40.7 0.2 7.2 1.9 0.0 0.0 0.0 17.1 0.0 0.1 0.0 52.6 0.0 0.1 0.0 3.4 0.0 0.1 32.9 10.3 15.1 0.1 0.2 0.7 2.6 0.1 0.5 0.3 0.0 0.3 TMEM11 "C17orf35, PM1, PMI" ENSG00000178307 "Transmembrane protein 11" P17152 17 21197954-21214176 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051795, HPA062854" Uncertain Supported Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA051795: AB_2681612, HPA062854: AB_2684882" "unprognostic (2.29e-1)" "unprognostic (1.09e-1)" "unprognostic (1.13e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (3.55e-1)" "unprognostic (3.36e-3)" "unprognostic (1.45e-2)" "unprognostic (4.34e-2)" "unprognostic (3.08e-2)" "unprognostic (1.16e-1)" "unprognostic (1.90e-2)" "unprognostic (1.40e-1)" "unprognostic (1.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.17e-2)" "unprognostic (4.61e-2)" 17.6 11.7 18.9 12.4 19.3 37.7 10.8 21.1 25.1 10.6 18.4 13.9 12.5 11.8 18.6 14.2 9.4 9.0 21.3 19.1 19.9 9.9 9.9 11.8 13.8 20.3 19.3 12.2 30.4 14.9 1.3 17.1 19.8 12.2 10.0 10.9 23.7 9.1 81.3 16.8 14.2 9.8 18.7 11.5 13.2 7.7 19.8 15.8 12.6 54.1 9.8 15.6 1.9 19.8 25.3 27.5 22.7 22.1 33.9 24.1 31.2 38.9 17.7 35.8 31.3 74.5 13.5 27.4 29.7 36.3 29.0 35.0 30.0 35.8 17.9 23.2 46.5 19.8 27.0 32.1 36.8 25.1 22.0 26.5 27.7 36.4 26.2 17.2 22.8 19.3 23.0 9.5 26.9 39.9 37.8 46.6 30.5 68.8 15.3 27.2 49.8 19.6 25.2 21.3 13.8 24.0 17.6 19.0 36.9 87.2 18.4 24.8 21.4 25.1 29.7 42.5 49.3 9.6 13.2 69.3 24.9 31.9 22.6 31.2 70.6 76.2 33.1 58.9 29.6 49.4 33.1 31.8 47.1 47.4 37.0 31.8 58.4 40.8 67.9 38.8 40.3 68.1 18.9 19.3 21.1 25.1 19.1 19.9 20.3 19.3 19.8 18.7 19.8 19.8 35.0 48.1 21.8 5.5 26.0 84.9 61.9 77.7 35.3 32.9 40.2 39.9 49.9 22.8 49.1 36.8 18.8 80.7 36.6 49.4 50.9 55.3 20.7 23.9 23.6 36.8 31.9 51.3 4.4 40.5 80.9 33.9 20.9 29.1 27.3 23.1 32.2 28.1 54.3 23.5 5.1 67.4 73.2 25.3 34.5 16.3 35.8 26.3 40.9 8.4 48.6 31.6 33.0 6.0 8.0 47.4 60.6 57.6 19.9 63.6 55.0 55.9 33.0 39.9 32.9 25.7 42.0 40.4 38.4 34.7 92.6 90.8 28.7 31.3 49.6 80.2 TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 8.3;Fibroblasts: 30.5;Late spermatids: 9.3;Melanocytes: 8.8;Microglial cells: 15.0;Peritubular cells: 24.0;Smooth muscle cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 559.2;ASC TERT1: 152.6;BJ hTERT+: 168.0;fHDF/TERT166: 81.9;HSkMC: 238.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" 29.6 8.0 7.6 16.2 8.9 3.0 27.1 8.5 9.2 61.0 5.3 12.6 15.1 18.9 14.1 6.9 11.9 35.8 9.4 7.7 9.3 6.0 0.9 37.6 47.8 17.2 12.1 1.4 7.5 5.6 6.1 6.6 14.9 12.7 15.1 0.9 6.8 26.0 1.6 13.9 23.1 11.2 13.4 11.4 10.5 5.9 16.4 5.1 21.7 1.7 27.2 32.2 18.4 21.9 0.1 0.3 1.3 0.7 559.2 152.6 0.8 11.8 168.0 0.4 3.0 0.2 0.6 0.3 0.4 81.9 0.3 0.2 0.1 0.2 0.1 0.5 0.0 0.3 0.6 1.0 7.2 0.3 1.2 238.4 0.3 7.0 0.1 0.7 0.1 0.2 0.5 0.5 0.5 0.7 0.3 1.6 0.1 0.0 0.9 0.6 0.9 0.8 0.1 0.7 0.2 39.5 0.0 0.3 0.3 4.5 0.2 1.8 1.2 13.1 0.4 11.2 0.5 2.6 3.1 0.6 6.8 0.5 0.1 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.4 0.2 0.1 0.4 0.3 0.3 1.4 0.2 0.4 0.2 0.1 0.1 7.6 8.9 8.5 9.2 7.7 9.3 17.2 12.1 14.9 13.4 16.4 21.9 1.3 0.0 0.0 0.0 0.2 3.8 0.1 0.0 0.6 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 8.3 0.2 5.8 1.3 0.0 0.0 0.0 0.0 0.2 30.5 0.0 0.2 0.0 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 1.9 4.4 9.3 4.1 1.1 8.8 15.0 1.6 0.0 0.0 0.0 0.0 0.1 1.1 24.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 9.7 0.1 0.1 0.0 3.7 0.3 0.7 0.5 0.0 0.1 TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 75.7;pancreas: 89.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 121.8;Alveolar cells type 2: 136.9;Distal enterocytes: 72.7;Proximal enterocytes: 164.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 26.8;BEWO: 21.8;CACO-2: 20.6;CAPAN-2: 48.3;OE19: 31.3;SK-BR-3: 41.2;T-47d: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Midbody, Cytosol" "HPA015796: AB_1858081" "unprognostic (2.53e-3)" "unprognostic (8.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (8.50e-2)" "unprognostic (8.37e-3)" "prognostic favorable (5.11e-5)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-1)" "unprognostic (5.16e-2)" 0.3 0.7 17.4 3.2 32.2 0.2 11.5 27.6 29.9 16.4 12.8 21.2 35.4 1.6 18.3 10.9 15.5 11.3 0.9 17.0 20.7 16.4 1.1 75.7 0.3 31.5 28.5 1.4 89.6 22.2 31.0 4.4 29.0 22.0 21.0 0.1 31.8 7.1 0.0 12.9 27.5 0.8 22.6 0.3 27.4 1.5 26.8 0.4 44.9 0.0 2.5 2.9 3.4 42.8 26.8 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 20.6 48.3 0.1 1.2 0.0 0.0 11.7 0.0 7.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 12.1 0.1 0.1 1.1 31.3 0.0 0.0 0.0 0.7 0.4 8.5 12.4 0.1 0.0 41.2 0.0 3.6 33.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 17.4 32.2 27.6 29.9 17.0 20.7 31.5 28.5 29.0 22.6 26.8 42.8 0.2 121.8 136.9 0.0 0.9 0.0 2.3 18.0 0.6 0.0 30.4 15.2 0.5 42.9 56.0 16.5 0.0 33.5 0.1 72.7 17.6 39.1 3.7 20.1 1.4 0.6 21.7 0.0 0.2 38.5 2.2 0.6 45.3 13.1 1.3 4.9 0.0 0.0 2.4 0.0 0.2 63.0 34.6 0.0 0.2 7.9 0.3 0.6 0.0 0.0 0.6 1.7 1.0 0.0 55.3 22.7 40.1 1.2 0.6 12.2 164.2 33.9 43.8 0.0 0.0 0.0 2.3 1.4 0.3 2.1 0.4 7.3 1.0 0.1 38.6 9.1 TMEM134 FLJ21749 ENSG00000172663 "Transmembrane protein 134" Q9H6X4 11 67461710-67469272 "Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043744 Approved Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA043744: AB_10794773" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (4.67e-2)" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (7.22e-2)" "unprognostic (3.85e-1)" "unprognostic (1.39e-2)" "unprognostic (4.30e-2)" "unprognostic (3.48e-1)" "unprognostic (1.75e-1)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-2)" "unprognostic (4.43e-3)" 12.6 24.3 22.5 8.6 23.2 4.7 14.8 21.2 29.9 15.6 19.9 14.0 8.3 9.6 11.0 55.5 10.2 6.5 46.8 21.6 22.2 25.2 33.9 11.2 11.9 22.8 22.6 8.6 42.9 7.9 8.7 5.3 22.4 25.7 4.5 2.8 20.6 7.3 57.4 57.5 14.5 4.4 22.7 16.2 22.4 26.5 22.9 6.6 13.5 26.0 8.8 15.9 25.4 22.5 12.3 4.6 6.5 14.0 4.3 7.3 7.2 2.5 4.6 2.9 1.2 5.8 14.3 11.7 27.2 6.2 9.2 10.0 2.9 10.7 1.8 11.3 4.9 2.2 4.5 5.9 6.6 2.3 3.2 7.3 13.4 2.3 7.7 12.7 3.0 7.9 3.0 6.6 6.3 29.0 13.3 8.6 11.0 20.4 16.3 6.5 3.8 38.5 11.3 12.5 6.0 13.3 9.1 14.2 28.6 4.4 34.5 2.3 5.8 10.4 9.0 12.5 3.3 27.8 19.4 8.2 15.6 3.0 8.5 58.2 54.3 98.5 71.4 132.7 78.8 203.7 84.2 80.6 66.6 195.7 85.6 80.6 25.7 90.2 176.0 87.3 123.9 73.3 22.5 23.2 21.2 29.9 21.6 22.2 22.8 22.6 22.4 22.7 22.9 22.5 43.3 16.0 41.5 11.8 83.0 90.0 87.7 177.7 99.0 29.3 139.9 173.4 53.4 60.1 93.5 68.0 10.4 69.5 46.5 64.7 133.1 95.0 50.2 53.0 35.3 36.6 71.4 22.3 9.4 126.0 147.9 31.3 120.3 73.4 23.4 52.5 29.3 69.6 84.0 11.8 8.2 100.3 97.6 43.6 49.3 46.2 20.8 49.0 110.3 2.8 61.2 39.5 63.8 9.5 14.1 189.9 81.7 24.8 47.2 142.6 150.8 148.9 75.0 29.5 6.6 24.4 45.9 105.8 80.1 185.1 180.1 72.8 53.3 37.6 73.5 152.2 TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 121.8;Excitatory neurons: 99.6;Inhibitory neurons: 93.7;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" 26.1 14.9 4.2 5.6 6.0 3.7 14.2 2.8 5.2 5.6 5.8 10.5 15.6 6.4 4.7 4.4 6.0 8.3 6.7 4.9 5.2 12.0 24.7 6.5 5.9 5.0 5.8 7.3 6.2 9.4 5.4 10.2 5.6 10.7 8.5 7.0 10.0 6.4 8.4 3.9 14.5 6.9 2.5 5.8 7.4 10.2 4.3 6.6 10.1 7.5 4.8 5.5 4.4 6.7 8.8 15.7 9.8 13.7 31.3 28.6 9.2 6.5 16.7 7.6 17.0 27.1 39.9 24.2 17.1 8.9 19.9 8.3 13.3 14.9 8.5 22.7 7.5 18.5 14.0 88.5 17.6 10.8 9.2 34.8 9.2 11.0 7.6 10.2 19.5 26.4 19.3 35.9 9.0 5.9 28.3 10.8 11.5 47.2 11.7 12.5 7.5 19.2 17.5 28.1 4.8 11.0 9.6 30.0 13.6 18.8 42.0 9.6 10.3 7.9 10.3 30.6 4.6 13.4 28.2 28.2 6.0 11.5 15.7 0.9 4.8 1.4 7.5 5.1 6.7 4.7 4.7 8.1 5.6 3.4 5.3 5.1 1.5 7.2 2.2 5.7 5.4 4.1 4.2 6.0 2.8 5.2 4.9 5.2 5.0 5.8 5.6 2.5 4.3 6.7 14.4 9.6 7.5 121.8 7.1 4.2 4.0 4.6 8.6 5.6 12.7 7.1 6.3 5.7 6.8 1.8 4.2 2.6 7.7 10.5 5.9 2.8 2.8 5.8 11.0 8.1 3.6 3.8 99.6 3.2 8.6 11.0 8.6 4.2 9.5 11.5 7.9 16.2 4.9 1.7 93.7 6.8 10.2 7.8 6.0 7.7 7.2 5.4 5.4 48.7 4.1 5.0 9.2 123.1 202.4 3.1 10.9 7.2 10.3 6.1 21.8 10.6 8.7 4.2 32.9 5.7 8.4 2.2 3.8 4.8 4.8 1.5 8.3 24.6 8.7 3.8 TMEM139 FLJ90586 ENSG00000178826 "Transmembrane protein 139" Q8IV31 7 143279957-143288048 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.8;kidney: 32.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 51.5;Ductal cells: 49.0;Proximal enterocytes: 90.7;Proximal tubular cells: 89.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 22.4;CAPAN-2: 40.8;EFO-21: 27.9;RPTEC TERT1: 70.5;SK-BR-3: 25.0;T-47d: 68.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036982, HPA036983" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Focal adhesion sites" "HPA036982: AB_2675413, HPA036983: AB_10672275" "unprognostic (2.58e-1)" "unprognostic (4.38e-1)" "unprognostic (6.62e-3)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (2.16e-3)" "unprognostic (2.83e-2)" "unprognostic (4.90e-2)" "unprognostic (1.60e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (2.89e-1)" "prognostic favorable (3.05e-5)" "unprognostic (1.73e-1)" "unprognostic (1.42e-2)" "unprognostic (2.83e-2)" "unprognostic (9.08e-3)" 1.1 2.7 1.9 2.2 6.4 0.0 3.2 6.6 3.2 8.9 2.9 5.7 33.8 1.2 1.3 0.4 6.8 7.2 3.3 1.6 4.1 32.2 9.2 5.1 0.2 10.5 6.9 0.4 8.7 6.8 1.8 5.2 8.9 0.9 4.5 0.8 4.8 3.1 0.1 1.2 19.3 0.4 5.9 0.9 2.5 3.8 5.7 0.0 7.2 0.0 0.1 1.8 0.3 13.9 22.4 1.6 0.3 0.1 0.0 0.0 14.3 0.2 0.0 0.0 0.0 5.2 40.8 0.3 27.9 0.0 1.8 18.5 0.0 9.3 0.0 0.3 0.0 0.0 2.4 3.1 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.9 0.0 1.3 0.0 0.5 0.0 1.5 1.6 1.0 0.0 0.5 1.6 0.4 0.3 0.0 70.5 5.6 0.4 0.1 1.1 25.0 0.2 0.5 68.5 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.1 0.3 0.3 0.3 0.3 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.8 0.0 0.6 0.1 1.9 6.4 6.6 3.2 1.6 4.1 10.5 6.9 8.9 5.9 5.7 13.9 0.6 16.0 5.9 0.7 0.2 0.1 2.1 2.8 0.0 0.2 8.2 15.5 2.3 27.1 5.4 51.5 0.0 30.5 0.2 28.9 35.2 49.0 14.8 16.2 1.6 0.7 3.6 0.0 0.0 4.7 5.2 0.4 3.1 17.9 0.0 2.2 1.4 16.2 1.9 0.0 0.2 6.7 0.0 0.6 0.3 13.6 0.0 0.7 5.4 0.0 1.1 7.7 0.0 0.0 5.2 30.6 23.3 0.0 0.0 1.2 90.7 89.1 3.8 0.1 0.0 0.0 0.9 0.1 0.2 0.6 0.0 6.4 0.8 0.7 12.9 1.4 TMEM154 FLJ32028 ENSG00000170006 "Transmembrane protein 154" Q6P9G4 4 152618628-152680012 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 58.3;skin 1: 58.5" "Cell type enhanced" "Detected in many" "B-cells: 108.6;Basal keratinocytes: 74.2;Glandular and luminal cells: 75.0;granulocytes: 101.2;monocytes: 82.1;Squamous epithelial cells: 119.2;Suprabasal keratinocytes: 194.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 6.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 403.7;eosinophil: 305.7;neutrophil: 477.5" "Lineage enriched" "Detected in many" 9 "granulocytes: 477.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 63.0;HMC-1: 71.1;Karpas-707: 55.6;U-266/70: 69.7;U-937: 56.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019184, HPA055411" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Nuclear membrane" Nucleoplasm "HPA019184: AB_2670088, HPA055411: " "unprognostic (1.09e-1)" "unprognostic (3.56e-1)" "unprognostic (5.17e-2)" "unprognostic (3.09e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-1)" "unprognostic (2.24e-1)" "unprognostic (2.96e-1)" "unprognostic (2.64e-1)" "unprognostic (1.65e-1)" "unprognostic (5.00e-3)" "unprognostic (7.67e-2)" "unprognostic (2.23e-3)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" 3.1 0.5 0.3 17.2 0.7 18.6 4.3 0.6 1.7 5.7 0.5 3.1 2.6 1.6 0.7 58.3 1.4 5.1 0.8 0.4 0.7 0.6 5.9 5.1 14.3 0.8 0.6 0.2 1.0 0.3 0.8 3.8 1.1 2.0 2.6 0.2 6.9 2.3 0.4 58.5 3.6 1.8 0.7 12.4 5.9 0.2 1.0 6.2 3.6 1.9 26.4 11.6 7.9 1.0 32.1 0.1 0.3 0.1 0.5 8.7 14.1 8.0 29.1 8.5 16.2 0.4 4.2 32.5 3.3 7.6 9.3 22.8 0.0 63.0 15.5 0.1 0.1 1.8 0.5 0.0 8.9 25.7 71.1 8.3 29.7 27.1 23.4 0.0 21.4 19.7 0.1 55.6 0.7 2.3 10.1 8.0 1.6 0.1 7.8 1.2 0.1 0.2 47.5 19.4 0.1 1.2 2.2 6.2 1.0 8.4 1.0 17.8 8.6 1.2 5.1 0.7 11.1 69.7 26.0 18.1 11.7 56.6 6.6 403.7 37.8 305.7 4.9 38.2 9.2 51.6 10.9 7.9 19.6 45.1 10.7 7.4 477.5 0.8 43.7 2.5 22.5 17.2 0.3 0.7 0.6 1.7 0.4 0.7 0.8 0.6 1.1 0.7 1.0 1.0 6.5 12.8 19.3 0.0 108.6 74.2 9.0 23.6 20.5 0.1 8.8 4.8 1.7 0.0 20.9 22.0 2.1 25.0 9.8 0.9 0.0 6.4 0.1 31.9 13.4 6.7 1.2 6.6 0.5 3.7 14.5 5.2 8.2 75.0 101.2 0.1 0.7 4.6 4.5 3.3 0.3 0.7 14.2 9.8 15.7 0.2 0.6 28.2 5.4 15.9 82.1 0.1 5.2 3.5 0.1 21.5 7.1 0.0 45.7 5.4 0.0 0.3 60.5 0.7 0.0 3.0 3.6 0.1 0.5 119.2 194.4 25.9 28.6 0.5 2.6 27.2 TMEM159 promethin ENSG00000011638 "Transmembrane protein 159" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 128.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal squamous epithelial cells: 176.4;Squamous epithelial cells: 127.5;Suprabasal keratinocytes: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 67.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" 40.2 33.0 3.8 5.4 8.0 3.2 27.0 6.0 4.0 47.4 2.3 42.6 4.3 28.6 7.9 61.9 26.3 20.1 91.6 3.4 3.3 16.5 2.5 19.9 11.7 2.7 3.3 40.8 12.4 14.1 3.2 4.0 3.9 22.1 12.0 5.7 36.8 10.4 128.5 96.0 17.9 17.8 2.4 7.1 21.1 10.5 5.4 5.0 15.4 100.6 16.7 47.9 57.3 2.8 14.3 7.1 7.6 28.7 67.9 44.1 3.4 7.4 27.6 2.9 4.9 5.6 21.4 20.2 7.9 21.6 12.9 23.1 11.7 13.0 3.4 7.7 4.5 9.1 1.9 11.1 15.4 7.2 24.2 17.3 58.8 15.4 48.1 12.2 15.0 10.8 6.9 6.1 5.8 25.2 5.6 6.7 7.0 14.1 3.5 28.9 4.2 7.3 38.1 41.1 1.2 1.1 18.2 25.8 9.8 13.5 46.0 6.5 10.6 5.4 5.4 25.6 1.9 0.5 1.7 7.2 22.2 6.4 5.3 19.5 8.8 7.0 9.7 6.9 9.8 12.2 12.7 8.2 5.4 9.6 9.9 9.6 3.9 7.3 10.3 14.3 14.8 6.6 3.8 8.0 6.0 4.0 3.4 3.3 2.7 3.3 3.9 2.4 5.4 2.8 17.3 9.6 20.9 0.0 12.9 121.2 38.5 31.9 176.4 1.0 53.3 55.2 59.4 15.7 31.8 22.0 0.0 4.8 9.1 34.5 7.9 19.7 0.8 11.4 12.8 13.7 14.5 11.8 1.9 21.3 2.1 44.3 19.4 19.3 15.8 14.0 17.5 0.2 10.2 1.7 0.8 30.6 12.2 15.7 39.0 2.2 67.4 13.8 30.2 4.7 22.7 44.7 7.2 1.0 0.1 24.7 41.8 37.2 3.8 45.3 23.1 21.1 11.2 1.5 32.9 26.5 35.7 2.0 9.9 127.5 150.2 1.9 14.8 5.1 29.9 66.6 TMEM163 "DKFZP566N034, SV31" ENSG00000152128 "Transmembrane protein 163" Q8TC26 2 134455759-134719000 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.3;pancreas: 27.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 36.9;Excitatory neurons: 62.2;Exocrine glandular cells: 30.8;Oligodendrocyte precursor cells: 219.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 20.3;RPTEC TERT1: 67.3;SCLC-21H: 30.2;U-937: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007224 Uncertain NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA007224: AB_2667780" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (7.25e-3)" "unprognostic (3.18e-1)" "unprognostic (1.47e-1)" "unprognostic (2.25e-1)" "unprognostic (6.08e-3)" "prognostic favorable (7.94e-4)" "unprognostic (9.05e-2)" "unprognostic (9.62e-2)" "unprognostic (6.02e-2)" "unprognostic (2.04e-1)" "unprognostic (2.60e-2)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" "unprognostic (6.75e-3)" "prognostic favorable (3.15e-4)" 3.4 8.5 13.5 5.1 13.4 0.3 1.4 18.8 13.3 0.2 5.4 1.0 0.6 0.4 0.3 0.1 2.8 9.3 6.7 12.9 15.2 1.6 0.4 14.5 10.4 18.3 20.7 0.9 27.8 0.8 13.9 3.7 15.4 0.2 0.5 4.0 3.0 0.2 0.3 0.1 1.0 0.4 16.5 1.6 7.3 6.5 28.3 2.0 0.9 0.5 16.4 12.2 0.1 23.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.2 20.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 3.5 6.7 0.1 0.1 0.3 0.0 0.6 0.1 0.0 5.2 1.1 2.3 0.0 0.1 0.1 67.3 10.0 30.2 1.1 0.0 0.0 1.6 0.1 0.0 0.0 7.0 0.0 0.4 0.0 1.5 1.6 0.0 0.0 0.0 12.6 1.3 0.0 0.0 0.0 0.3 0.0 0.4 0.4 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.2 13.5 13.4 18.8 13.3 12.9 15.2 18.3 20.7 15.4 16.5 28.3 23.0 19.3 3.2 36.9 2.6 6.7 0.0 0.0 0.0 0.0 2.7 0.2 5.1 5.4 7.2 0.0 0.0 0.0 0.1 0.9 0.1 0.0 8.5 4.8 0.3 0.2 3.5 0.0 0.4 62.2 30.8 0.4 0.7 20.9 1.0 0.0 0.6 0.4 0.3 5.0 1.7 23.5 0.4 0.0 1.3 0.0 3.8 0.0 2.7 0.0 14.0 2.6 1.0 5.2 219.7 13.0 12.6 0.1 0.4 0.3 0.0 0.0 0.3 0.0 5.7 0.0 0.5 0.4 2.1 1.6 0.0 0.4 0.1 0.7 1.9 0.1 2.5 TMEM164 "FLJ22679, RP13-360B22.2" ENSG00000157600 "Transmembrane protein 164" Q5U3C3 X 110002631-110182734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Distal enterocytes: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 59.7" "Lineage enriched" "Detected in many" 18 "granulocytes: 59.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038784 Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "Cell Junctions" "HPA038784: AB_10670790" "unprognostic (2.14e-3)" "unprognostic (3.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.65e-3)" "unprognostic (7.94e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (8.17e-6)" "unprognostic (9.85e-3)" "unprognostic (5.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-2)" "unprognostic (3.95e-1)" "unprognostic (7.66e-2)" "prognostic favorable (3.14e-4)" "unprognostic (1.76e-1)" "unprognostic (1.81e-2)" "unprognostic (4.19e-3)" 16.9 10.3 11.4 9.6 11.8 19.0 12.3 6.8 9.7 5.5 14.3 18.8 21.5 5.3 6.0 13.8 8.1 5.1 22.7 9.0 12.1 11.1 2.0 17.9 6.7 13.5 13.0 13.8 25.4 8.3 9.6 5.2 11.2 8.9 21.2 3.6 9.8 14.4 27.5 20.3 19.2 6.9 8.2 8.4 14.0 1.9 12.3 12.6 13.8 19.3 8.0 5.8 6.8 8.6 10.8 24.3 19.5 12.8 23.7 17.3 11.9 5.3 12.4 11.0 7.1 19.1 16.6 8.6 35.2 8.3 27.1 15.6 17.1 27.9 10.8 23.9 11.7 58.5 13.0 8.1 13.9 26.1 80.1 24.0 48.4 19.9 27.2 30.2 21.8 15.2 18.4 10.2 19.7 21.6 27.4 33.1 17.5 36.9 17.3 12.4 15.1 7.2 17.5 11.3 18.2 20.3 34.0 33.1 15.9 18.1 9.6 25.7 49.0 9.3 6.8 11.0 7.7 5.9 7.9 6.9 24.3 32.0 25.3 59.7 3.3 14.2 0.6 2.9 1.6 0.2 0.7 0.6 2.7 0.6 0.4 0.5 16.3 2.3 1.8 0.5 1.0 1.8 11.4 11.8 6.8 9.7 9.0 12.1 13.5 13.0 11.2 8.2 12.3 8.6 2.9 3.2 36.1 84.5 3.7 4.8 3.7 4.7 4.6 1.2 11.7 9.1 21.3 11.5 6.9 16.5 2.1 2.7 3.5 53.0 3.9 4.6 0.5 6.7 3.8 6.0 27.6 14.5 22.9 11.4 6.3 3.1 7.7 10.7 3.8 4.3 6.4 1.7 13.6 0.0 31.4 12.7 10.2 25.1 9.4 1.3 1.8 12.5 1.8 24.4 28.1 1.0 4.1 34.2 7.6 13.5 15.0 1.5 1.6 9.0 31.9 3.3 5.4 1.3 0.0 6.4 4.1 0.2 0.3 10.4 8.0 2.7 5.2 3.8 21.2 12.3 TMEM167B "AD-020, C1orf119, FLJ90710" ENSG00000215717 "Transmembrane protein 167B" Q9NRX6 1 109090764-109096934 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (7.89e-2)" "unprognostic (3.28e-1)" "unprognostic (4.96e-2)" "prognostic favorable (8.86e-4)" "unprognostic (3.76e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-3)" "unprognostic (2.37e-2)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (1.74e-1)" "unprognostic (3.01e-1)" "unprognostic (3.21e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.15e-2)" "unprognostic (2.25e-1)" 31.7 35.5 29.9 24.2 30.3 53.7 33.1 30.0 34.4 32.4 29.6 27.7 23.2 30.9 31.6 24.0 25.4 25.6 35.9 30.1 30.5 33.3 33.0 28.4 26.2 29.1 30.2 29.7 25.7 45.1 15.9 33.8 29.6 36.9 29.8 31.3 30.3 27.9 21.3 28.9 23.7 30.6 31.3 28.3 32.4 23.4 30.9 25.1 41.7 25.9 27.7 27.2 16.3 33.0 36.1 6.5 23.4 32.3 47.8 47.0 20.9 54.2 49.7 30.0 27.8 13.7 13.4 24.0 30.1 55.9 17.8 17.4 15.1 24.1 43.0 37.4 11.4 22.4 8.7 18.8 53.6 43.6 36.6 38.8 64.7 27.9 46.7 40.8 26.5 30.8 28.5 33.9 33.0 22.2 33.0 28.1 17.7 31.0 33.1 20.5 37.1 19.0 38.6 22.5 16.6 17.0 26.2 38.0 53.0 20.8 23.7 32.0 25.2 30.6 30.8 67.0 26.6 34.0 20.6 23.7 51.7 44.7 65.0 38.1 20.7 35.4 13.3 23.8 19.1 14.4 17.6 17.0 19.1 13.5 17.8 17.8 45.4 17.5 30.8 11.7 17.9 19.9 29.9 30.3 30.0 34.4 30.1 30.5 29.1 30.2 29.6 31.3 30.9 33.0 29.6 32.1 31.4 10.7 30.1 30.5 29.4 25.7 16.5 30.1 28.2 17.9 34.0 22.8 28.6 18.4 12.5 42.1 38.7 20.0 19.6 26.7 19.1 16.2 25.2 30.7 20.9 25.9 11.5 30.1 44.3 32.3 23.0 27.1 32.3 21.7 27.8 21.7 39.1 25.2 12.5 25.2 24.4 36.8 42.8 17.0 28.9 38.8 26.6 6.5 56.3 36.0 24.7 12.5 16.4 29.3 19.7 25.2 16.8 39.8 25.9 29.6 19.7 30.1 0.0 21.7 26.8 28.9 28.2 26.0 35.7 63.1 32.9 20.4 19.1 51.5 TMEM203 "HBEBP1, MGC14327" ENSG00000187713 "Transmembrane protein 203" Q969S6 9 137204082-137205648 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.31e-1)" "unprognostic (2.65e-2)" "unprognostic (4.53e-2)" "unprognostic (8.72e-2)" "unprognostic (1.10e-1)" "unprognostic (6.54e-2)" "unprognostic (2.72e-2)" "unprognostic (1.78e-1)" "unprognostic (1.43e-1)" "unprognostic (7.16e-2)" "prognostic favorable (4.78e-6)" "unprognostic (2.94e-1)" "prognostic favorable (1.50e-5)" "unprognostic (3.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.04e-2)" "unprognostic (1.19e-1)" 25.7 32.6 32.8 17.2 33.6 10.9 25.5 33.8 36.8 28.1 33.1 30.2 22.2 29.9 26.4 31.4 24.2 16.4 45.9 32.9 33.4 33.2 49.2 20.5 27.0 33.6 33.6 27.7 26.2 30.7 25.6 15.9 33.4 27.1 18.2 16.4 26.8 21.8 49.7 43.6 28.5 16.9 32.8 30.4 30.1 19.1 34.9 20.3 25.1 45.9 22.7 27.8 27.6 33.0 38.0 39.3 36.5 60.7 53.1 41.1 43.6 48.4 46.6 55.1 41.1 32.6 33.3 39.0 45.7 42.2 53.0 72.6 45.3 48.1 32.1 71.0 43.5 27.0 45.5 37.4 44.3 63.1 26.8 39.6 75.4 36.0 47.4 36.8 35.8 50.5 64.2 44.4 43.2 65.2 50.5 54.6 60.8 72.4 63.2 54.2 51.1 78.2 46.5 27.2 48.3 47.3 38.6 48.8 39.2 25.0 68.8 50.6 32.0 56.3 30.1 63.6 55.1 23.8 80.0 49.5 43.5 46.3 47.3 4.7 3.8 4.1 5.2 4.3 6.4 8.3 5.8 6.5 4.6 4.5 8.7 6.0 1.9 7.5 3.9 4.8 4.0 2.6 32.8 33.6 33.8 36.8 32.9 33.4 33.6 33.6 33.4 32.8 34.9 33.0 23.2 9.6 6.8 4.6 21.4 17.6 22.7 7.0 23.9 33.6 29.6 33.8 13.5 40.0 7.9 31.3 4.2 30.5 23.7 15.9 52.8 49.4 3.5 15.3 24.2 20.7 16.3 29.8 5.7 42.0 26.3 22.3 14.8 13.3 5.7 31.7 21.4 41.1 29.3 32.0 6.2 13.4 10.2 27.1 13.2 9.4 22.1 20.8 24.9 5.6 54.2 58.8 24.7 2.5 6.1 41.7 10.8 20.7 13.3 37.2 18.5 59.2 4.9 25.7 13.1 19.5 32.5 18.6 15.9 28.5 27.3 19.4 24.4 36.2 18.6 17.9 TMEM210 ENSG00000185863 "Transmembrane protein 210" A6NLX4 9 137170858-137172056 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 14.8" "Group enriched" "Detected in some" 68 "Early spermatids: 900.5;Late spermatids: 1815.1" "Cancer enhanced" "Detected in single" "prostate cancer: 1.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "plasmacytoid DC: 3.2" "Lineage enriched" "Detected in single" 33 "dendritic cells: 3.2" "Cell line enriched" "Detected in some" 8 "RPMI-8226: 13.5" "Not detected" "Not detected" HPA066907 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA066907: AB_2685747" "unprognostic (5.17e-2)" "unprognostic (5.04e-2)" "unprognostic (2.87e-5)" "unprognostic (4.18e-2)" "unprognostic (3.63e-2)" "unprognostic (3.14e-2)" "unprognostic (8.00e-2)" 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.3 0.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 900.5 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.7 1815.1 12.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 1.1 0.0 0.0 0.0 0.0 19.7 0.0 0.1 9.1 4.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 TMEM211 bA9F11.1 ENSG00000206069 "Transmembrane protein 211" Q6ICI0 22 24934954-24946695 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 2.6;salivary gland: 5.8;stomach 1: 3.2" "Cell type enriched" "Detected in some" 19 "Ionocytes: 36.7" "Group enriched" "Detected in some" 5 "colorectal cancer: 4.8;endometrial cancer: 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066784 Uncertain NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA066784: AB_2685722" "unprognostic (7.89e-3)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" "unprognostic (1.09e-2)" "unprognostic (5.97e-3)" "unprognostic (5.88e-2)" "unprognostic (1.31e-3)" "unprognostic (3.26e-2)" "unprognostic (2.06e-1)" "unprognostic (6.42e-2)" "unprognostic (2.65e-2)" "unprognostic (8.61e-3)" "unprognostic (3.59e-1)" "unprognostic (4.43e-2)" 0.0 0.0 0.1 0.3 0.3 0.0 0.4 0.3 0.2 2.6 0.0 0.3 0.0 0.6 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 5.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 1.3 1.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 36.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 TMEM213 ENSG00000214128 "Transmembrane protein 213" A2RRL7 7 138797952-138838101 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 76.0;salivary gland: 52.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 53.3;Distal tubular cells: 144.8;Melanocytes: 26.6" "Cancer enriched" "Detected in some" 22 "renal cancer: 21.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "basophil: 2.1;neutrophil: 1.1;NK-cell: 2.0" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.0" "Cell line enhanced" "Detected in single" "RPTEC TERT1: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA054059 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA054059: AB_2682361" "unprognostic (2.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.85e-2)" "unprognostic (1.19e-2)" "unprognostic (3.19e-2)" "unprognostic (6.84e-2)" "unprognostic (1.17e-2)" "unprognostic (2.10e-1)" "unprognostic (6.14e-2)" "unprognostic (6.08e-2)" "unprognostic (1.91e-2)" "prognostic favorable (5.54e-7)" "unprognostic (4.33e-1)" "unprognostic (9.99e-2)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" 0.1 0.1 0.5 0.2 0.5 1.1 4.7 0.6 0.7 2.8 0.4 0.1 1.3 0.2 0.6 0.3 0.1 0.2 0.0 0.6 0.1 76.0 0.1 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.1 0.1 0.4 0.4 0.1 0.3 52.3 1.2 0.1 5.3 0.3 0.1 0.0 0.2 0.4 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 2.1 0.2 0.2 0.3 0.2 0.4 0.2 0.1 0.2 0.1 0.3 0.2 0.1 1.1 2.0 0.2 0.2 0.1 0.1 0.5 0.5 0.6 0.7 0.6 0.1 0.2 0.1 0.4 0.0 0.5 1.0 0.1 3.2 9.9 0.0 0.1 0.0 0.9 3.0 0.0 0.4 14.1 7.9 0.4 0.0 4.4 53.3 0.0 0.0 0.2 0.0 144.8 0.0 0.0 0.9 0.4 0.5 0.0 0.0 0.6 0.2 0.1 0.2 0.0 1.3 1.3 0.1 0.0 0.0 0.1 1.7 0.4 0.0 2.0 0.0 0.8 0.0 0.0 0.1 26.6 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.9 3.5 1.3 0.0 0.5 0.2 0.0 0.2 0.0 0.4 0.0 0.6 0.0 0.2 0.6 TMEM236 "bA162I21.2, bA16O1.2, FAM23A, FAM23B" ENSG00000148483 "Transmembrane protein 236" Q5W0B7 10 17752201-17800868 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 33.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 81.1;Enteroendocrine cells: 23.4;Intestinal goblet cells: 28.8;Paneth cells: 48.1;Proximal enterocytes: 96.5;Undifferentiated cells: 19.0" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.7;pancreatic cancer: 0.5;stomach cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "MOLT-4: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045096 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA045096: AB_2732516" "unprognostic (4.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.88e-3)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (3.36e-2)" "unprognostic (2.52e-3)" "unprognostic (1.37e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (5.06e-3)" "unprognostic (1.75e-1)" "unprognostic (1.62e-2)" "unprognostic (1.72e-1)" "unprognostic (3.43e-2)" "unprognostic (3.16e-2)" "unprognostic (1.54e-2)" 0.7 0.6 0.3 1.7 0.3 0.5 0.4 0.8 0.5 0.5 0.4 14.1 21.8 0.3 0.2 0.3 0.2 0.4 0.3 0.3 0.1 0.2 0.1 0.7 0.3 0.1 0.0 0.3 0.5 0.1 0.0 1.5 0.2 0.1 14.0 0.3 0.1 0.2 0.3 0.3 33.5 1.0 0.0 0.3 0.4 0.2 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.7 0.2 0.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.3 0.3 0.2 0.0 0.2 0.9 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.1 0.2 0.1 0.2 10.3 0.1 0.1 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.0 0.4 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.3 0.8 0.5 0.3 0.1 0.1 0.0 0.2 0.0 0.1 0.7 0.2 0.0 0.5 0.0 0.2 0.1 0.5 0.0 0.0 0.3 7.3 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.1 81.1 0.0 0.1 1.1 0.1 0.1 0.2 23.4 0.4 0.4 0.9 0.2 0.2 0.0 0.5 1.3 0.1 1.1 0.0 7.2 0.0 0.4 28.8 0.0 4.8 0.8 1.1 0.0 5.9 0.0 3.7 0.0 0.1 0.0 0.0 0.6 0.7 48.1 0.0 0.0 0.4 96.5 0.0 0.0 0.9 0.0 0.7 0.3 0.4 0.1 0.2 0.0 0.3 0.4 0.2 19.0 0.6 TMEM254 "bA369J21.6, C10orf57, FLJ13263" ENSG00000133678 "Transmembrane protein 254" Q8TBM7 10 80078646-80092557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029105, HPA072613" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA029105: AB_2672909, HPA072613: AB_2732205" "unprognostic (9.40e-2)" "unprognostic (1.76e-1)" "unprognostic (9.52e-2)" "unprognostic (5.74e-3)" "unprognostic (5.39e-2)" "unprognostic (6.04e-2)" "unprognostic (3.66e-1)" "unprognostic (3.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.87e-3)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (7.65e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (3.45e-3)" "unprognostic (5.96e-2)" 15.2 11.9 7.9 11.1 8.3 9.4 26.5 7.3 8.3 16.0 7.0 22.6 16.3 10.7 62.1 39.5 28.0 14.0 5.7 8.0 7.0 14.8 52.8 9.4 10.4 8.0 8.7 13.0 19.0 16.5 4.4 15.6 8.5 43.1 22.3 11.2 16.6 14.2 4.4 72.3 15.4 10.4 8.3 7.8 15.0 15.5 7.5 15.4 14.8 2.9 14.6 12.4 22.7 9.3 14.4 13.8 20.0 17.2 27.1 29.7 33.4 13.5 9.3 9.0 9.7 10.6 43.5 11.0 22.1 16.9 9.3 15.2 8.9 11.5 10.0 17.5 16.5 3.0 3.8 14.3 11.2 12.8 13.0 20.3 48.6 8.9 7.3 20.6 7.7 9.1 7.9 22.9 9.4 29.8 10.7 9.9 11.0 12.6 43.2 13.2 2.8 9.7 13.5 11.9 8.0 12.1 12.6 31.4 13.3 14.8 45.1 9.1 12.1 7.8 12.8 12.0 8.0 15.8 24.7 0.8 17.8 13.6 6.6 57.3 25.0 13.0 18.1 28.6 22.3 21.3 20.2 18.8 20.7 14.3 33.8 22.6 2.8 17.5 31.5 23.1 27.2 20.5 7.9 8.3 7.3 8.3 8.0 7.0 8.0 8.7 8.5 8.3 7.5 9.3 4.6 9.6 9.6 17.6 7.3 8.2 5.9 9.7 5.2 7.9 22.6 17.5 4.4 12.8 13.7 9.2 16.7 40.9 3.8 9.0 21.5 15.7 10.5 37.6 10.0 5.4 8.4 5.9 17.2 8.7 37.2 7.6 11.2 10.5 5.7 12.9 5.7 33.4 19.4 16.8 16.4 23.7 8.2 10.3 5.8 7.5 9.3 8.5 3.6 4.7 15.2 15.7 12.3 8.5 14.8 10.3 15.3 11.7 5.2 15.6 19.6 23.1 40.2 13.3 13.1 2.6 7.1 36.8 8.7 20.9 24.0 22.7 6.9 11.2 18.1 8.4 TMEM255B "FAM70B, MGC20579" ENSG00000184497 "Transmembrane protein 255B" Q8WV15 13 113759226-113816995 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.0;Endothelial cells: 81.5;granulocytes: 39.3;Hepatic stellate cells: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 31.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 31.2" "Cell line enhanced" "Detected in many" "HMC-1: 28.6;HUVEC TERT2: 38.8;PC-3: 39.3;RPMI-8226: 25.1;TIME: 35.9;U-87 MG: 40.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA043334 Approved Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA043334: AB_10795982" "unprognostic (2.20e-1)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (4.90e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.49e-3)" "unprognostic (3.00e-2)" "unprognostic (9.39e-2)" "prognostic unfavorable (4.12e-5)" "unprognostic (4.65e-2)" "unprognostic (1.84e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" 14.2 6.1 1.3 3.7 1.3 0.7 10.6 1.1 2.2 10.1 2.1 4.0 1.6 8.4 0.3 3.9 8.1 3.6 6.6 1.6 3.7 10.1 3.4 13.2 2.4 2.1 1.3 4.3 3.1 1.6 3.5 1.0 1.7 7.0 1.4 0.4 4.2 2.2 2.9 4.2 4.8 5.0 1.4 8.2 4.3 3.3 1.9 0.8 11.2 3.9 1.8 7.5 7.1 1.5 10.3 0.0 0.6 0.0 2.8 0.0 0.1 4.8 10.7 5.5 3.5 0.4 0.2 0.2 0.1 7.7 12.5 1.5 1.1 0.7 2.3 0.1 0.9 0.3 0.4 0.0 1.4 2.9 28.6 1.8 2.3 11.7 4.6 15.7 38.8 0.6 0.1 0.2 12.0 0.2 1.5 0.9 1.0 1.6 39.3 1.8 0.8 25.1 5.4 0.5 2.2 5.1 0.2 1.5 0.1 1.0 0.6 8.2 35.9 1.6 10.3 0.6 1.7 0.0 0.0 1.9 40.6 2.7 0.3 31.2 5.4 0.7 0.0 5.5 0.0 0.9 0.0 0.0 1.5 2.8 0.0 0.0 2.7 0.0 4.0 0.0 0.0 1.4 1.3 1.3 1.1 2.2 1.6 3.7 2.1 1.3 1.7 1.4 1.9 1.5 65.0 6.4 4.8 2.3 1.9 5.9 1.2 0.9 1.2 0.9 1.1 1.7 9.1 0.0 0.2 1.8 0.0 0.1 0.3 0.0 1.9 8.2 0.8 0.3 0.8 81.5 1.2 3.2 2.7 1.7 0.1 4.7 0.0 0.2 39.3 2.3 105.0 0.7 12.9 0.0 0.1 0.2 0.0 17.4 14.6 1.1 7.8 16.3 8.8 7.5 3.4 0.5 0.0 0.0 0.6 1.3 0.1 3.0 1.4 1.7 0.0 0.1 0.5 0.8 6.6 0.9 3.6 5.1 19.1 0.2 4.7 0.0 1.8 2.1 0.3 1.0 TMEM271 ENSG00000273238 "Transmembrane protein 271" A0A286YF58 4 573880-576295 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 23.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "glioma: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.7;NB-4: 1.5;NTERA-2: 2.6;SCLC-21H: 5.7;U-2 OS: 1.4;U-251 MG: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: SCLC-21H - Neuronal signaling" "unprognostic (4.13e-3)" "unprognostic (6.97e-3)" "unprognostic (2.65e-2)" 0.0 0.9 13.2 0.0 12.4 0.0 0.0 0.2 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 11.2 0.0 0.0 0.0 0.0 4.0 5.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.0 0.0 3.7 0.0 0.0 2.4 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.7 1.5 2.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.4 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 12.4 0.2 23.3 18.0 11.2 4.0 5.1 2.7 2.4 6.2 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 219.8;skin 1: 64.7;vagina: 80.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 104.7;Cytotrophoblasts: 128.3;Macrophages: 121.3;Squamous epithelial cells: 116.5;Suprabasal keratinocytes: 201.9;Syncytiotrophoblasts: 656.6;Urothelial cells: 157.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.3;urothelial cancer: 12.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "HBEC3-KT: 244.9;hTCEpi: 56.1;hTERT-HME1: 68.0;RT4: 36.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044165, HPA073122" Enhanced Approved Cytosol NA NA 2500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA044165: AB_10961279, HPA073122: " "unprognostic (2.51e-3)" "unprognostic (1.96e-2)" "unprognostic (2.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.27e-1)" "unprognostic (1.92e-1)" "unprognostic (5.15e-4)" "unprognostic (5.96e-2)" "unprognostic (3.15e-1)" "unprognostic (2.60e-1)" "unprognostic (1.81e-3)" "unprognostic (2.47e-1)" "unprognostic (1.20e-3)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (1.46e-2)" "unprognostic (6.77e-2)" 0.1 0.1 0.4 0.0 0.4 3.3 3.2 0.5 0.6 42.1 0.3 0.0 0.1 0.1 1.3 219.8 3.1 0.1 4.2 0.5 0.3 0.2 0.3 2.1 0.1 0.4 0.3 0.1 0.1 3.2 0.2 15.9 0.3 3.7 0.0 0.1 27.3 2.5 1.3 64.7 0.0 0.1 0.1 1.8 0.2 0.8 0.4 1.5 0.1 0.6 25.9 15.2 80.1 0.3 26.6 0.1 0.0 0.1 0.0 0.0 22.4 0.2 1.1 1.3 1.4 1.0 4.1 0.1 0.2 0.0 0.6 7.6 0.0 244.9 5.1 0.2 0.0 1.9 0.2 0.8 0.0 0.0 0.0 0.0 56.1 0.0 68.0 0.4 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 0.0 0.2 4.3 0.0 1.6 0.0 1.6 36.0 0.2 0.2 0.1 31.3 0.0 4.6 2.8 0.7 0.0 0.0 1.6 0.0 2.1 0.3 0.1 0.4 0.1 0.0 0.0 1.6 0.9 1.1 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 6.0 0.0 0.0 0.8 0.0 32.9 0.4 0.4 0.5 0.6 0.5 0.3 0.4 0.3 0.3 0.1 0.4 0.3 0.1 0.0 0.0 0.3 0.3 64.2 104.7 71.7 17.6 0.0 1.5 5.6 4.7 0.0 39.4 1.8 0.0 128.3 0.0 0.1 0.0 0.5 0.8 2.9 0.0 1.8 0.0 0.0 0.3 0.0 14.7 1.8 0.0 0.1 0.0 0.0 2.2 0.7 10.8 0.0 0.3 0.0 12.2 4.8 7.3 2.0 0.3 121.3 10.6 0.0 2.6 0.0 2.1 0.0 0.2 2.2 0.0 0.0 0.0 53.5 0.0 0.0 55.0 0.0 0.0 0.1 3.6 0.7 6.8 116.5 201.9 656.6 1.0 0.2 0.0 157.9 TMEM41A MGC15397 ENSG00000163900 "Transmembrane protein 41A" Q96HV5 3 185476496-185499057 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 200.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059101, HPA059790" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059101: AB_2683905, HPA059790: AB_2684125" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (6.70e-6)" "unprognostic (2.67e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.84e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.63e-2)" "unprognostic (2.56e-2)" "unprognostic (3.73e-1)" "unprognostic (3.68e-1)" "unprognostic (1.46e-2)" "unprognostic (1.02e-2)" 9.0 27.2 9.6 5.4 9.3 11.0 10.2 9.7 11.0 10.0 8.9 7.9 26.4 8.7 11.2 23.6 9.2 7.6 9.9 9.0 9.4 14.7 20.5 10.6 7.4 9.4 11.6 14.1 9.7 8.7 5.7 8.4 9.2 10.2 8.9 7.5 12.0 8.3 9.8 19.9 24.1 7.4 9.8 12.5 10.3 9.3 12.1 7.8 7.0 16.4 12.6 10.8 14.6 10.9 43.6 15.4 10.1 12.5 15.6 16.8 29.6 16.3 14.3 20.2 14.6 40.5 16.7 13.4 30.5 15.3 28.5 29.4 28.1 17.5 20.4 22.6 25.8 23.3 8.6 41.2 17.5 25.3 12.5 15.7 25.6 18.3 20.9 12.7 15.6 16.8 42.1 32.4 13.0 16.8 15.6 14.5 16.8 34.1 24.1 15.5 15.6 24.6 17.4 31.4 10.1 13.1 14.1 35.8 25.7 14.4 42.8 19.6 11.4 11.9 15.0 25.2 34.5 47.2 78.0 26.5 18.2 15.1 14.6 14.0 8.2 7.2 16.3 9.4 21.0 17.5 16.7 18.1 9.3 15.6 18.2 19.8 2.8 12.2 12.2 21.7 15.3 9.2 9.6 9.3 9.7 11.0 9.0 9.4 9.4 11.6 9.2 9.8 12.1 10.9 12.1 9.6 30.5 7.2 16.7 53.0 42.8 29.5 50.7 22.4 38.2 20.6 12.6 24.3 24.9 20.2 18.8 27.5 18.3 23.3 7.9 33.4 0.7 17.7 14.5 19.8 18.6 16.4 8.1 56.0 23.5 18.0 36.2 38.0 8.8 50.2 17.2 40.9 19.6 16.8 9.8 28.3 16.2 14.2 17.3 2.8 14.3 12.5 8.8 2.8 65.9 11.4 11.3 20.1 7.6 50.3 17.0 13.5 20.9 64.2 200.8 23.2 9.6 28.6 19.7 16.8 16.5 22.1 14.3 113.0 84.7 46.0 18.5 82.6 45.6 93.4 TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.2;Hepatic stellate cells: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 3.7;NK-cell: 8.1" "Group enriched" "Detected in many" 10 "granulocytes: 3.7;NK-cells: 8.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043718 Uncertain Approved Cytosol "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA043718: AB_10794662" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (8.31e-3)" "unprognostic (4.53e-2)" "unprognostic (2.78e-3)" "unprognostic (9.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.70e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (6.55e-13)" "unprognostic (1.23e-2)" "unprognostic (3.36e-1)" "unprognostic (1.65e-3)" "unprognostic (5.66e-2)" 10.3 2.9 9.8 2.3 11.7 5.2 8.9 7.8 12.4 6.9 7.1 11.0 2.7 5.6 13.7 5.6 5.4 4.5 9.6 10.3 10.1 6.0 3.4 11.3 3.0 9.9 9.7 4.9 3.5 0.9 2.6 7.4 10.0 5.2 7.2 0.6 7.7 2.2 3.2 3.6 6.8 3.2 8.8 9.3 4.9 2.2 10.5 2.0 5.6 2.3 1.6 5.3 5.9 9.2 11.1 9.1 13.4 14.2 4.8 16.2 11.8 8.2 15.3 6.8 10.8 5.0 21.8 2.0 38.9 10.0 20.3 12.6 4.5 6.4 4.6 18.1 6.3 12.4 10.6 3.8 8.7 3.9 18.9 10.0 6.8 15.4 6.8 32.8 28.2 12.1 3.4 0.5 22.9 10.1 5.9 9.9 6.9 11.1 14.8 11.5 8.4 0.3 7.2 6.3 3.7 7.7 6.1 1.9 12.6 5.6 9.0 8.5 33.7 20.8 7.6 6.4 11.2 1.5 1.2 4.0 31.4 15.0 10.4 3.7 0.2 0.2 0.4 0.1 0.0 0.1 0.1 0.6 0.0 0.2 0.0 0.2 0.4 8.1 0.3 0.4 0.0 0.0 9.8 11.7 7.8 12.4 10.3 10.1 9.9 9.7 10.0 8.8 10.5 9.2 22.0 0.0 2.3 3.3 2.1 0.5 3.3 4.9 1.8 0.9 2.8 2.3 1.7 1.5 6.0 5.5 2.1 9.5 1.7 31.2 0.0 5.7 0.6 2.3 3.7 23.8 6.0 4.0 12.7 4.9 4.0 6.0 22.4 2.0 17.7 10.6 53.2 0.6 3.5 0.0 5.4 25.2 6.1 1.3 3.4 0.3 3.1 1.5 1.8 12.2 0.1 0.5 2.1 2.5 1.5 14.9 21.0 1.9 1.3 6.0 3.9 0.4 7.5 0.6 6.6 1.8 3.6 0.5 6.5 2.4 0.6 8.8 1.9 6.0 21.0 6.3 TMEM45A "DERP7, FLJ10134" ENSG00000181458 "Transmembrane protein 45A" Q9NWC5 3 100492619-100577444 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skin 1: 475.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 425.3;Club cells: 841.5;Early spermatids: 207.3;Suprabasal keratinocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 406.9;ASC TERT1: 118.3;HSkMC: 125.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA062101 Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "HPA062101: AB_2684682" "unprognostic (5.92e-3)" "unprognostic (5.44e-2)" "unprognostic (2.11e-1)" "unprognostic (1.43e-3)" "unprognostic (7.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.18e-11)" "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.02e-5)" "unprognostic (2.68e-2)" 19.4 18.1 1.4 11.7 3.3 2.0 42.8 1.7 2.5 38.4 2.3 10.3 3.6 18.3 3.2 16.5 20.9 18.9 21.9 1.5 1.8 3.7 99.0 13.1 2.6 1.9 1.9 11.9 23.3 2.7 22.9 40.9 1.8 9.1 6.6 1.7 26.9 6.3 3.2 475.1 6.4 25.4 1.7 5.0 7.0 13.3 1.9 1.6 9.1 2.5 50.7 19.5 79.5 2.1 28.6 2.0 2.7 9.6 406.9 118.3 0.3 66.9 62.0 9.4 84.8 2.5 0.6 0.0 32.6 44.1 24.6 31.9 2.4 13.0 23.4 7.2 8.4 23.9 9.3 8.0 25.7 0.4 1.5 125.4 7.4 17.1 25.4 39.0 3.5 0.0 0.6 3.2 22.6 0.3 0.1 0.7 3.2 0.0 16.8 0.0 23.3 0.4 0.6 1.0 2.9 19.4 16.4 8.5 7.3 18.2 0.8 13.6 9.3 62.9 44.3 0.5 15.2 53.8 32.9 0.1 49.7 1.9 42.6 0.0 0.9 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.6 1.4 3.3 1.7 2.5 1.5 1.8 1.9 1.9 1.8 1.7 1.9 2.1 1.6 60.9 61.4 0.7 3.0 94.6 5.4 425.3 9.6 3.2 19.1 8.9 2.5 1.5 841.5 0.0 0.0 2.6 0.4 0.2 0.0 7.5 207.3 3.0 79.1 8.9 1.2 1.3 0.8 14.9 46.3 56.3 2.0 2.0 65.0 10.7 15.0 137.1 5.8 8.4 2.4 2.0 63.1 6.5 25.4 25.4 16.1 6.6 23.2 13.1 1.1 3.5 0.0 16.1 11.8 6.5 2.6 27.8 26.8 3.1 0.3 0.2 121.0 0.9 6.6 22.8 56.6 1.5 3.3 5.4 254.9 7.5 6.4 26.7 0.1 4.4 TMEM54 CAC-1 ENSG00000121900 "Transmembrane protein 54" Q969K7 1 32894594-32901438 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1231.3;Intestinal goblet cells: 357.2;Paneth cells: 800.1;Proximal enterocytes: 418.6;Undifferentiated cells: 355.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 198.9;OE19: 242.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060864, HPA061992" Approved Approved Vesicles NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA060864: , HPA061992: AB_2684652" "unprognostic (2.67e-1)" "unprognostic (2.57e-2)" "unprognostic (2.55e-1)" "unprognostic (4.98e-2)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.42e-2)" "unprognostic (3.48e-2)" "unprognostic (9.43e-2)" "unprognostic (6.82e-3)" "unprognostic (2.13e-2)" "unprognostic (9.06e-2)" "unprognostic (3.12e-2)" "unprognostic (3.40e-2)" 19.2 15.6 68.2 39.9 64.2 0.0 24.6 61.3 98.4 59.0 52.8 268.0 116.0 40.4 26.6 145.3 25.5 62.0 18.7 64.1 70.0 44.3 14.9 26.8 4.6 70.5 68.8 20.3 31.8 49.5 22.6 18.4 64.8 58.2 113.2 4.2 54.0 22.9 6.9 116.0 123.1 21.3 67.8 13.2 108.0 11.9 65.5 2.4 47.8 4.9 13.0 51.1 78.6 66.4 133.3 33.9 0.0 32.0 59.1 35.4 119.9 20.0 29.2 43.1 55.2 84.7 198.9 0.0 57.1 24.8 55.2 80.0 28.6 107.4 12.8 158.3 6.4 0.2 11.3 4.5 42.9 0.4 2.0 30.5 96.2 66.1 18.1 29.1 19.3 13.0 18.7 0.1 22.7 135.6 0.1 2.6 10.3 242.7 60.8 17.7 52.2 0.6 16.2 159.8 1.8 17.1 14.4 82.1 44.0 19.3 89.3 24.2 39.9 42.3 47.5 95.9 40.8 5.2 12.4 15.8 30.1 3.3 61.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.2 64.2 61.3 98.4 64.1 70.0 70.5 68.8 64.8 67.8 65.5 66.4 6.4 19.2 27.6 3.9 6.6 20.4 92.3 36.9 20.5 8.2 82.0 61.0 4.7 97.2 36.9 47.8 4.2 42.8 1.3 1231.3 27.4 150.2 43.4 7.5 16.1 12.3 60.7 0.0 3.3 202.4 149.1 22.9 160.0 14.3 5.7 11.8 18.9 3.7 8.4 0.0 2.9 357.2 12.2 1.0 6.5 32.3 19.9 3.7 14.2 0.0 3.1 33.7 0.0 3.5 2.6 166.3 800.1 24.5 1.6 160.9 418.6 84.9 14.0 10.3 6.6 8.5 20.6 10.9 8.8 65.0 63.6 64.3 3.3 2.4 355.8 193.3 TMEM63B "C6orf110, dJ421H19.2, DKFZp434P0531" ENSG00000137216 "Transmembrane protein 63B" Q5T3F8 6 44126914-44155519 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 87.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 163.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029249, HPA029250, HPA029251" Uncertain Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Actin filaments" "HPA029249: AB_2672965, HPA029250: AB_2672966, HPA029251: AB_2672967" "unprognostic (8.83e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-3)" "unprognostic (3.61e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.97e-3)" "unprognostic (1.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-1)" "unprognostic (8.60e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.67e-2)" "unprognostic (6.12e-3)" "unprognostic (3.15e-1)" 12.4 19.6 18.1 9.5 18.9 17.9 12.6 18.9 24.7 17.8 15.1 24.6 17.1 11.4 12.1 34.6 10.7 12.8 26.5 25.1 21.0 17.1 39.2 38.3 5.8 19.9 17.5 12.1 12.6 20.2 15.6 13.6 20.4 17.4 19.4 31.6 20.9 8.6 51.6 41.4 18.5 9.9 15.7 9.8 25.4 31.0 19.8 8.6 16.2 21.2 8.6 18.8 23.2 18.3 41.7 23.1 21.1 34.6 32.3 18.6 34.6 17.0 22.8 18.7 17.7 16.1 15.7 7.2 25.5 25.3 30.1 37.8 25.6 62.6 12.3 20.6 19.5 20.8 17.2 49.1 22.2 4.6 19.2 24.8 55.5 26.2 16.7 37.8 18.9 15.3 67.7 11.2 22.0 42.7 4.6 10.3 11.4 163.7 11.2 5.8 14.0 13.2 52.2 44.5 24.3 18.8 15.2 35.5 35.8 26.0 40.1 11.6 21.8 23.8 27.0 17.9 20.7 14.0 11.1 8.8 35.9 6.6 30.7 0.2 0.4 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.2 0.2 0.4 0.2 18.1 18.9 18.9 24.7 25.1 21.0 19.9 17.5 20.4 15.7 19.8 18.3 7.2 16.0 19.7 17.6 3.3 13.6 14.9 41.3 21.1 18.4 11.2 9.3 3.8 10.0 25.1 11.0 16.7 14.1 4.2 75.1 1.9 17.0 72.9 10.6 8.9 6.9 18.6 28.4 26.3 15.2 16.6 11.0 45.9 25.1 0.0 11.0 11.7 43.4 26.4 16.8 28.4 32.4 30.5 11.7 11.4 87.6 11.8 9.1 7.2 15.0 8.5 9.4 5.2 21.6 12.1 32.5 45.7 9.1 6.4 21.9 32.7 10.8 15.7 27.6 6.6 10.4 12.0 2.1 14.7 19.4 18.3 20.0 5.5 7.1 24.3 29.4 TMEM79 "FLJ16057, FLJ32254, MATT, MGC13102" ENSG00000163472 "Transmembrane protein 79" Q9BSE2 1 156282935-156293185 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 132.4;skin 1: 89.9;vagina: 59.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 24.1;Squamous epithelial cells: 59.9;Suprabasal keratinocytes: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 30.2;SK-BR-3: 26.7;T-47d: 28.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA055214 Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center" "HPA055214: AB_2682741" "unprognostic (3.12e-1)" "unprognostic (2.96e-1)" "unprognostic (1.26e-1)" "unprognostic (8.17e-2)" "unprognostic (5.51e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.61e-5)" "unprognostic (6.37e-2)" "unprognostic (2.44e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (4.31e-7)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (3.98e-2)" "unprognostic (2.37e-1)" 2.1 2.8 5.5 1.5 6.3 2.9 4.5 6.2 7.5 34.5 5.1 2.4 2.6 2.4 2.6 132.4 2.5 1.8 1.8 5.2 5.7 2.4 3.6 1.9 2.9 6.2 6.2 2.4 2.1 6.0 3.7 1.6 6.0 28.4 1.3 1.7 23.5 2.6 2.9 89.9 2.7 1.2 5.8 3.8 2.9 2.0 6.1 3.6 2.2 0.7 10.9 6.9 59.4 7.8 12.5 7.2 2.4 4.7 1.8 1.8 5.9 3.5 1.4 6.2 2.4 8.5 3.4 2.2 7.6 0.9 2.2 10.8 2.8 5.1 2.7 8.3 3.9 2.3 3.3 2.5 3.3 2.6 3.3 1.7 30.2 4.6 4.7 4.4 1.4 8.2 10.5 14.8 2.9 14.1 7.3 4.0 3.6 9.0 5.7 8.5 2.3 5.0 1.3 3.0 4.3 4.7 4.3 26.7 7.0 2.9 28.3 7.4 3.4 11.5 3.8 4.2 9.5 11.3 13.0 5.2 8.0 6.0 8.8 0.0 2.0 3.0 1.7 0.7 1.8 1.7 1.5 1.8 1.6 2.2 2.0 2.4 3.7 1.7 1.3 2.0 2.1 1.7 5.5 6.3 6.2 7.5 5.2 5.7 6.2 6.2 6.0 5.8 6.1 7.8 1.8 3.2 1.5 8.8 3.9 13.3 1.4 24.1 9.1 3.0 10.0 6.5 1.2 2.8 14.3 1.8 2.1 7.7 3.6 2.4 1.9 2.5 0.1 3.7 2.4 2.0 3.0 0.8 1.8 3.3 1.8 2.1 1.5 6.7 0.0 3.1 2.2 2.4 3.4 8.4 2.2 2.9 10.2 2.5 1.8 0.3 1.5 1.4 5.4 3.7 4.4 1.5 1.0 2.5 5.8 4.5 2.1 0.7 1.6 10.7 4.3 1.6 4.2 2.2 0.0 1.0 1.9 1.3 2.1 59.9 33.1 7.4 3.2 2.9 3.1 6.4 TMEM86A FLJ90119 ENSG00000151117 "Transmembrane protein 86A" Q8N2M4 11 18693122-18704785 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.6;Theca cells: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057119 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA057119: AB_2683342" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (8.08e-3)" "unprognostic (1.89e-1)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (4.05e-2)" "unprognostic (2.94e-1)" "unprognostic (3.73e-1)" "unprognostic (1.74e-1)" "unprognostic (8.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "unprognostic (7.92e-2)" "unprognostic (4.20e-1)" "unprognostic (3.24e-1)" 2.8 2.7 2.6 2.2 2.2 0.3 3.2 2.1 2.8 2.3 3.8 1.5 1.4 2.2 1.0 2.3 2.6 4.0 2.9 2.1 2.6 9.5 2.6 3.5 4.7 3.1 2.7 7.1 3.4 5.4 2.2 4.3 2.5 1.6 1.8 5.7 2.7 1.4 2.9 17.6 2.0 1.9 2.7 4.9 2.1 2.3 4.0 1.6 2.1 2.5 2.5 2.3 3.6 4.5 0.0 0.2 0.6 3.1 2.7 0.0 0.1 0.6 0.5 0.5 0.5 0.0 0.4 0.0 1.2 0.6 3.0 0.3 0.2 0.1 0.3 0.2 1.9 0.2 0.1 0.0 2.1 0.0 2.8 3.8 1.2 0.1 0.2 0.7 1.7 1.8 0.6 0.0 1.3 1.7 0.0 0.0 0.2 0.5 1.6 0.0 5.1 0.0 17.5 3.8 1.0 1.3 1.0 3.2 1.4 1.1 3.9 0.4 1.9 0.5 0.2 0.1 0.1 3.2 2.7 0.0 1.1 0.0 1.1 0.0 1.9 0.1 0.2 1.4 0.5 0.0 0.2 0.4 3.4 0.1 0.4 0.8 0.0 0.1 0.5 2.0 0.5 0.8 2.6 2.2 2.1 2.8 2.1 2.6 3.1 2.7 2.5 2.7 4.0 4.5 1.9 0.0 0.0 0.3 0.0 0.1 0.8 0.4 0.0 5.2 3.5 1.8 2.2 0.0 0.7 11.0 8.4 0.5 1.4 0.6 7.9 7.8 12.2 1.1 1.9 2.1 3.5 0.0 0.5 8.0 0.3 1.7 1.1 1.0 0.0 3.0 3.9 1.6 40.6 0.0 0.8 0.8 0.0 12.7 0.8 12.1 2.1 8.3 0.0 3.7 2.3 2.6 0.0 2.0 0.1 7.4 0.1 1.9 0.4 0.6 0.0 8.3 0.4 4.8 6.6 0.4 1.2 7.8 2.6 0.2 0.3 2.3 0.7 17.4 0.2 0.4 TMEM91 "DSPC3, FLJ27310, IFITMD6" ENSG00000142046 "Transmembrane protein 91" Q6ZNR0 19 41350911-41384083 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 212.0;Late spermatids: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 193.3" "Group enriched" "Detected in all" 8 "granulocytes: 193.3;monocytes: 51.9" "Cell line enhanced" "Detected in many" "HEL: 20.1;HSkMC: 20.5;TIME: 19.8" "Low region specificity" "Detected in all" HPA053240 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "HPA053240: AB_2682085" "unprognostic (3.02e-3)" "unprognostic (1.92e-2)" "unprognostic (5.13e-3)" "unprognostic (2.97e-2)" "unprognostic (1.29e-1)" "unprognostic (9.90e-2)" "unprognostic (4.70e-2)" "unprognostic (2.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.69e-3)" "prognostic favorable (3.54e-5)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.52e-7)" "unprognostic (1.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.06e-2)" 24.0 12.8 32.3 6.9 43.1 36.2 19.7 19.5 35.2 39.1 27.7 26.6 3.5 18.6 10.2 22.6 30.2 8.2 16.4 29.3 49.0 20.3 9.6 23.3 6.5 29.2 33.3 20.1 17.7 4.1 26.2 9.4 28.4 23.0 3.9 9.2 11.4 8.6 5.4 66.3 14.3 8.7 23.3 37.5 12.3 37.8 52.7 5.7 20.5 7.3 7.6 29.8 31.3 24.2 3.3 7.0 5.4 2.7 6.4 13.6 5.0 2.6 3.4 1.3 2.1 0.5 2.9 1.5 2.4 3.0 2.1 0.9 1.3 2.4 3.0 2.3 3.6 20.1 5.7 11.1 12.3 3.4 5.2 20.5 12.6 4.0 9.8 14.8 9.2 3.7 3.8 6.2 2.1 6.3 2.5 6.6 2.3 0.9 4.2 4.2 1.2 1.4 3.4 1.6 1.4 3.3 5.0 1.0 4.1 3.8 1.3 9.9 19.8 3.1 3.0 2.9 2.7 3.8 0.6 1.1 6.5 4.6 1.2 36.8 51.9 4.0 5.9 12.3 7.4 0.7 3.4 3.1 9.5 1.4 8.0 3.9 193.3 1.5 9.1 14.6 4.7 41.2 32.3 43.1 19.5 35.2 29.3 49.0 29.2 33.3 28.4 23.3 52.7 24.2 20.2 3.2 22.4 23.8 3.5 17.8 22.9 59.8 7.4 8.3 10.7 15.9 5.3 2.8 25.0 7.3 6.2 2.7 10.6 0.7 1.9 5.3 212.0 12.0 12.1 13.7 14.4 4.8 11.7 3.2 84.3 21.7 1.1 4.8 34.2 13.0 20.0 3.8 15.7 8.4 18.9 1.6 10.2 67.6 8.4 451.5 14.0 51.6 8.8 7.5 30.7 4.1 20.6 5.0 5.8 3.8 18.5 7.2 1.7 6.5 2.3 2.5 13.5 6.4 6.6 4.8 8.6 4.9 9.0 9.7 21.3 8.6 7.8 3.7 1.7 10.4 TMEM97 MAC30 ENSG00000109084 "Transmembrane protein 97" Q5BJF2 17 28319200-28328685 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 113.4;pancreas: 322.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 121.5;Exocrine glandular cells: 196.4;Granulosa cells: 212.9;Hepatocytes: 226.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 341.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044795, HPA076689" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "HPA044795: AB_10959306, HPA076689: " "unprognostic (1.35e-2)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (1.81e-1)" "unprognostic (4.34e-2)" "unprognostic (3.20e-2)" "unprognostic (9.03e-2)" "unprognostic (1.04e-2)" "unprognostic (1.81e-1)" "unprognostic (1.11e-2)" "unprognostic (5.17e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.99e-1)" "unprognostic (4.01e-2)" 4.3 26.0 5.2 7.3 6.3 6.7 11.7 6.6 9.0 5.7 6.5 14.3 16.4 6.7 4.7 7.4 13.1 10.2 3.4 6.3 5.4 7.1 113.4 17.4 7.1 14.9 14.2 18.1 322.0 6.5 1.6 6.8 14.9 10.8 12.6 6.3 3.7 3.3 15.5 9.8 11.2 5.7 5.0 4.6 38.8 58.0 7.4 7.6 4.2 9.1 8.2 26.6 5.2 6.8 46.1 120.4 214.8 105.5 28.0 40.2 70.5 44.1 27.9 67.9 90.3 341.0 34.3 126.3 46.4 17.0 140.1 48.7 137.1 75.0 52.7 60.3 102.1 47.8 56.9 143.0 25.7 76.9 36.4 84.0 10.0 66.4 27.5 8.3 21.1 80.1 101.3 92.1 22.7 81.8 120.0 72.4 95.6 187.7 30.6 94.8 236.5 112.8 85.6 210.6 154.1 67.0 70.0 55.1 36.3 118.2 97.0 35.8 13.8 72.8 56.8 62.9 81.7 74.3 159.0 115.9 14.6 54.7 44.3 0.7 2.2 2.2 7.8 2.7 9.2 11.1 6.4 9.4 16.1 5.5 10.4 9.8 1.0 9.5 1.0 9.3 6.6 5.2 5.2 6.3 6.6 9.0 6.3 5.4 14.9 14.2 14.9 5.0 7.4 6.8 4.2 9.6 61.5 3.3 7.7 14.5 6.0 32.8 18.8 11.3 22.5 21.5 9.0 121.5 19.1 14.7 16.7 34.2 5.0 6.1 15.6 23.3 22.3 7.5 14.3 7.1 38.8 40.3 2.9 196.4 84.0 14.4 49.5 11.4 1.3 212.9 6.4 226.9 22.0 3.3 4.5 16.2 26.4 6.7 34.7 49.1 13.4 9.9 16.0 0.0 11.4 8.2 4.1 4.0 1.0 47.7 3.5 11.3 15.3 13.9 4.0 6.3 12.2 9.1 6.6 10.4 12.4 91.3 65.5 22.7 11.2 10.7 6.4 65.1 29.4 7.9 TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 55.1" "Cell type enhanced" "Detected in some" "Early spermatids: 272.5;Hofbauer cells: 236.3;Kupffer cells: 161.3;Late spermatids: 118.9;Spermatocytes: 198.3" "Cancer enriched" "Detected in all" 5 "glioma: 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 62.8" "Lineage enriched" "Detected in many" 44 "granulocytes: 62.8" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;HMC-1: 2.5;Karpas-707: 1.2;NB-4: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "prognostic unfavorable (3.58e-4)" "unprognostic (7.64e-3)" "unprognostic (7.47e-3)" "unprognostic (2.11e-2)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (9.48e-2)" "unprognostic (5.70e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (4.46e-2)" "unprognostic (9.50e-2)" "unprognostic (4.48e-2)" "unprognostic (5.69e-3)" "unprognostic (3.30e-1)" "unprognostic (1.44e-5)" "unprognostic (9.22e-2)" 0.8 3.3 1.7 1.3 3.0 2.0 0.8 2.2 3.2 0.6 1.2 0.8 0.3 0.2 0.0 0.7 0.4 0.7 0.4 2.3 2.6 0.2 2.6 0.7 0.9 4.4 4.5 0.2 0.2 0.4 0.2 4.6 4.8 0.3 0.5 0.3 0.3 1.3 0.1 0.1 1.5 0.8 3.0 1.4 0.6 55.1 3.9 0.6 0.2 0.5 0.4 0.4 0.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 62.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.3 0.3 0.6 0.0 0.6 1.7 3.0 2.2 3.2 2.3 2.6 4.4 4.5 4.8 3.0 3.9 6.1 1.0 0.0 2.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 272.5 0.0 0.0 5.1 0.0 2.7 0.7 0.2 1.9 0.3 0.0 0.0 0.0 0.0 5.3 1.2 236.3 0.0 0.7 0.0 0.0 161.3 0.0 118.9 3.7 59.5 0.0 29.0 1.3 0.5 0.0 0.5 4.4 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.0 0.3 13.1 0.0 0.1 198.3 2.6 0.1 0.0 2.9 0.7 0.2 0.0 0.1 TMLHE "BBOX2, FLJ10727, TMLH, XAP130" ENSG00000185973 "Trimethyllysine hydroxylase, epsilon" Q9NVH6 X 155489011-155719098 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 51.5;Oligodendrocyte precursor cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034589, HPA040331" Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA034589: AB_10670571, HPA040331: AB_2676929" "unprognostic (1.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.04e-1)" "unprognostic (5.41e-2)" "unprognostic (6.66e-3)" "unprognostic (1.10e-3)" "unprognostic (6.50e-2)" "unprognostic (1.00e-1)" "unprognostic (3.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.20e-3)" "unprognostic (6.97e-2)" "prognostic favorable (3.68e-6)" "unprognostic (1.69e-1)" "unprognostic (5.74e-2)" "unprognostic (2.73e-1)" "unprognostic (7.75e-2)" 11.7 10.2 7.1 6.6 7.4 8.4 11.3 9.0 8.0 11.3 8.1 11.6 11.8 9.4 10.4 10.3 9.9 8.0 25.3 6.7 7.7 16.7 18.8 5.6 7.0 8.5 8.2 12.0 9.5 18.9 5.4 8.4 8.5 6.6 12.5 10.9 12.7 9.7 32.0 5.9 11.2 12.3 8.3 8.7 9.1 2.9 7.3 8.9 10.5 33.4 7.6 8.2 6.6 9.8 25.0 11.9 9.8 28.6 11.8 18.1 0.0 9.9 14.6 12.3 32.4 8.7 13.9 0.0 38.9 17.6 28.2 13.4 21.2 9.7 13.9 10.3 14.3 11.3 19.5 10.2 16.4 10.5 7.6 19.5 20.0 13.6 20.8 18.2 19.5 15.5 15.8 9.0 20.5 9.3 12.8 11.8 3.0 21.6 0.1 12.7 15.5 9.4 15.0 8.5 9.2 13.7 9.3 0.5 11.2 10.5 10.6 11.9 16.5 10.3 9.7 20.4 12.4 11.0 12.6 9.6 12.4 16.4 9.6 3.4 12.6 14.7 4.6 14.9 3.5 8.1 5.0 3.9 13.1 10.6 6.5 5.7 18.2 6.2 21.5 6.1 5.5 5.8 7.1 7.4 9.0 8.0 6.7 7.7 8.5 8.2 8.5 8.3 7.3 9.8 6.7 0.0 2.3 27.1 10.1 5.2 12.1 14.4 9.6 4.0 5.2 7.5 7.2 7.2 9.7 9.2 0.0 8.8 6.5 7.9 23.5 10.7 0.0 6.8 7.4 6.2 6.1 14.3 22.2 7.6 6.8 10.2 9.2 7.3 10.1 8.1 4.2 12.0 12.4 0.0 29.5 7.3 4.1 16.1 10.4 0.5 8.4 12.1 12.4 51.5 13.1 7.6 10.3 47.7 25.5 8.5 7.3 5.7 5.6 4.3 17.4 17.0 9.5 5.4 0.0 5.9 9.5 0.3 2.5 7.6 4.1 6.7 8.0 10.5 6.5 11.0 TMPO "LAP2, LEMD4, TP" ENSG00000120802 Thymopoietin "P42166, P42167" 12 98515579-98550351 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" DNA-binding Cardiomyopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 139.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 172.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008150, CAB009847, HPA070805" Enhanced Enhanced "Nuclear membrane" NA Yes 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "CAB009847: AB_2205450, HPA008150: AB_1079235, HPA070805: " "unprognostic (2.36e-1)" "unprognostic (4.46e-3)" "unprognostic (5.90e-2)" "unprognostic (2.80e-2)" "unprognostic (1.35e-1)" "unprognostic (2.95e-2)" "unprognostic (1.07e-2)" "unprognostic (1.54e-1)" "unprognostic (1.74e-2)" "unprognostic (3.69e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-3)" "prognostic unfavorable (9.34e-4)" "unprognostic (6.01e-3)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (3.26e-2)" 17.1 13.9 8.4 44.0 9.4 93.2 24.3 19.1 15.1 23.2 10.1 34.5 34.1 30.8 34.4 27.0 22.8 17.7 11.0 9.1 9.6 21.7 37.2 21.9 78.7 9.7 8.9 56.2 25.3 17.8 8.4 29.4 9.6 17.2 36.4 20.7 16.5 19.1 12.2 22.7 39.6 22.3 8.8 39.1 35.7 23.1 9.6 139.9 15.2 12.2 78.1 20.7 20.7 14.2 180.5 117.5 283.3 145.5 23.1 30.7 166.2 145.0 77.1 193.9 139.5 129.5 88.9 314.4 86.2 85.6 70.7 113.0 240.8 110.1 177.1 217.7 148.5 269.1 103.3 86.5 21.2 315.4 170.8 17.6 35.4 115.0 61.2 66.9 112.8 192.0 231.8 118.1 122.0 114.7 514.9 248.6 170.1 167.2 108.6 421.3 187.2 218.6 69.3 167.7 221.9 132.2 248.9 155.2 79.3 110.6 174.3 149.2 60.4 111.1 96.5 76.8 150.8 125.9 231.9 344.0 32.0 179.5 151.0 48.6 30.4 13.4 18.9 54.1 20.5 22.4 21.9 21.6 23.4 27.2 30.0 23.5 2.4 20.7 75.9 12.9 28.5 30.5 8.4 9.4 19.1 15.1 9.1 9.6 9.7 8.9 9.6 8.8 9.6 14.2 45.4 32.1 27.9 3.6 70.1 27.8 23.7 18.7 28.5 21.1 21.2 28.6 9.0 25.8 33.5 31.3 12.5 36.0 48.5 63.0 31.3 19.5 42.7 29.5 29.8 38.0 28.7 172.1 20.3 31.5 89.7 32.2 56.1 42.7 29.1 70.1 34.2 50.0 38.2 10.1 15.3 63.4 16.2 63.1 34.9 32.1 28.6 73.4 17.8 23.4 63.5 20.3 54.6 14.6 19.1 26.7 28.5 40.6 81.9 21.1 33.7 33.1 25.6 52.6 19.7 27.3 32.0 54.0 59.4 62.8 23.3 11.8 60.8 32.4 62.4 21.8 TMPRSS11F "FLJ16046, HATL4" ENSG00000198092 "Transmembrane serine protease 11F" Q6ZWK6 4 68053198-68129869 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 15.2;skin 1: 9.3;vagina: 4.8" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 6.9" "Group enriched" "Detected in some" 7 "cervical cancer: 1.6;head and neck cancer: 2.1;lung cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "K-562: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA026911 Uncertain NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA026911: AB_2205589" "unprognostic (9.46e-2)" "unprognostic (5.30e-1)" "unprognostic (7.16e-2)" "unprognostic (8.79e-3)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.5 0.1 0.0 0.1 1.0 0.0 0.1 9.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 4.1 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.3 0.1 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 6.9 0.0 0.3 0.0 0.1 0.0 0.5 TMPRSS13 "MSPL, MSPS, TMPRSS11" ENSG00000137747 "Transmembrane serine protease 13" Q9BYE2 11 117900641-117929459 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.7;skin 1: 41.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.9;Extravillous trophoblasts: 21.2;Glandular and luminal cells: 10.9;Ionocytes: 16.2;Syncytiotrophoblasts: 19.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 13.8;BEWO: 29.9;MCF7: 27.0;SK-BR-3: 42.8;T-47d: 43.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.08e-3)" "unprognostic (5.18e-2)" "unprognostic (6.59e-2)" "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (5.61e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-1)" "unprognostic (3.16e-6)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.08e-1)" "unprognostic (3.44e-1)" 0.3 0.4 0.2 0.7 0.2 0.6 7.1 0.0 0.7 6.7 0.0 0.4 0.3 0.6 0.6 15.7 0.3 0.4 0.1 0.9 0.0 2.6 0.2 3.9 1.2 0.0 0.0 0.1 2.5 0.0 0.3 2.9 0.0 1.4 0.4 0.0 11.0 0.1 0.2 41.0 0.8 0.2 0.0 1.5 0.2 0.4 0.0 0.9 6.6 0.0 4.8 0.5 9.3 0.1 13.8 0.1 0.0 0.0 0.0 0.0 29.9 0.0 0.0 0.0 0.0 10.2 0.1 0.7 0.1 0.0 0.0 1.3 0.0 0.1 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.5 0.7 0.0 27.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 1.4 0.0 4.0 0.4 0.1 0.0 42.8 0.6 1.7 43.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.1 0.2 0.2 0.2 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.6 0.0 0.2 1.7 4.6 1.7 1.2 0.0 7.4 4.6 1.4 7.2 5.3 0.0 0.0 15.9 0.2 0.3 0.0 8.3 0.3 2.4 1.3 0.2 0.0 0.0 0.2 1.2 21.2 0.3 0.5 10.9 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.5 16.2 1.2 1.9 0.8 0.0 1.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 5.7 3.9 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 5.2 8.0 19.4 0.4 0.5 0.8 9.0 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.8;Gastric mucus-secreting cells: 155.4;Paneth cells: 368.3;Prostatic glandular cells: 203.4;Proximal enterocytes: 159.6;Urothelial cells: 166.6" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 22.8;MCF7: 10.5;OE19: 35.9;RT4: 57.8;SK-BR-3: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.6 0.2 0.4 13.9 0.4 0.1 20.1 0.2 0.4 5.0 3.1 104.0 78.5 1.0 2.8 36.1 10.7 24.1 0.2 0.3 0.3 47.7 33.5 39.9 0.2 0.4 0.3 0.2 111.4 4.0 1.5 0.2 0.3 280.4 78.0 0.2 76.2 7.7 0.1 7.3 89.6 3.3 0.1 0.2 146.2 1.5 0.3 0.8 19.2 0.1 10.2 35.7 7.6 0.5 0.1 0.0 0.1 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.1 22.8 3.3 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 3.7 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 10.5 0.3 1.0 2.3 35.9 0.2 0.1 0.0 2.6 1.3 57.8 0.2 0.7 0.3 11.7 0.3 0.4 8.8 0.0 0.0 0.1 0.6 0.6 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.1 51.3 109.8 0.0 1.7 0.3 30.9 6.8 0.0 0.0 34.0 25.8 0.6 32.9 42.1 47.8 0.0 0.7 1.1 404.8 23.5 39.2 21.3 7.4 0.5 1.3 18.0 2.7 0.2 60.4 0.1 1.0 155.4 5.8 7.0 0.0 0.4 32.0 0.1 0.0 0.1 84.1 44.7 0.3 0.3 4.8 0.0 2.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 65.1 368.3 0.0 0.0 203.4 159.6 3.8 36.6 0.0 0.0 1.6 2.0 0.4 1.4 2.1 0.1 0.3 1.1 0.0 105.7 166.6 TMPRSS3 "DFNB10, DFNB8" ENSG00000160183 "Transmembrane serine protease 3" P57727 21 42371887-42396091 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 23.7;stomach 1: 14.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 17.7;Cholangiocytes: 24.3;Ductal cells: 16.1;Endometrial ciliated cells: 17.1;Gastric mucus-secreting cells: 23.4;Ionocytes: 16.2;Muller glia cells: 20.4;Respiratory ciliated cells: 39.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 16.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.1" "Lineage enriched" "Detected in single" 6 "T-cells: 3.1" "Cell line enriched" "Detected in some" 4 "U-266/84: 274.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 16: U-266 - Nucleosome" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (8.47e-3)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.85e-1)" "unprognostic (2.45e-3)" "unprognostic (3.97e-2)" "unprognostic (1.43e-1)" "unprognostic (8.17e-2)" "unprognostic (9.62e-2)" "unprognostic (4.81e-2)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.66e-2)" "unprognostic (2.73e-1)" "unprognostic (8.00e-2)" "unprognostic (1.33e-1)" 0.5 0.3 3.8 0.2 4.0 0.1 8.7 4.0 3.7 6.3 2.0 0.2 1.3 0.7 0.0 0.2 23.7 8.6 0.0 3.4 4.1 2.4 0.5 3.4 0.5 4.9 4.7 0.0 3.0 0.0 1.5 0.2 3.7 0.4 0.1 3.9 9.2 0.4 0.1 0.1 1.1 0.0 3.5 0.4 14.5 0.0 4.7 0.9 2.9 0.0 0.4 1.0 0.0 2.7 4.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 32.9 0.0 66.2 26.5 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.6 0.0 14.0 0.0 1.5 3.5 0.0 0.0 1.0 0.4 0.0 0.0 0.0 2.8 1.5 0.0 0.0 33.9 1.6 0.0 0.0 3.2 0.3 0.1 0.0 1.7 0.0 0.2 0.7 274.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 3.1 0.0 1.7 1.8 0.0 0.0 0.3 0.9 0.3 0.0 0.5 0.0 0.8 0.5 3.8 4.0 4.0 3.7 3.4 4.1 4.9 4.7 3.7 3.5 4.7 2.7 0.1 12.8 3.7 2.3 0.4 0.3 2.3 8.1 0.0 0.2 17.7 9.9 0.6 24.3 10.8 7.3 0.0 0.0 0.1 1.4 5.9 16.1 1.4 17.1 0.4 0.2 0.0 2.7 0.0 13.8 0.1 1.3 23.4 5.2 0.0 0.2 0.4 0.0 0.1 0.0 0.0 2.0 16.2 0.0 0.5 0.6 0.3 0.3 0.0 0.0 0.0 20.4 0.0 0.0 0.1 11.8 1.4 0.0 0.4 2.4 2.9 0.0 39.8 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.1 2.5 5.0 TMPRSS5 "MGC141886, MGC148044" ENSG00000166682 "Transmembrane serine protease 5" Q9H3S3 11 113687547-113706373 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.6;choroid plexus: 20.8" "Cell type enhanced" "Detected in some" "Astrocytes: 26.4;Excitatory neurons: 5.4;Horizontal cells: 5.0;Oligodendrocytes: 15.5" "Cancer enhanced" "Detected in some" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.0;CAPAN-2: 3.2;OE19: 2.0;WM-115: 2.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010992 Approved Nucleoplasm NA NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA010992: AB_1858152" "unprognostic (1.53e-2)" "unprognostic (3.81e-2)" "unprognostic (2.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (2.99e-3)" "unprognostic (3.08e-1)" "unprognostic (5.19e-3)" "unprognostic (8.49e-2)" "unprognostic (8.13e-2)" "unprognostic (3.38e-2)" "unprognostic (1.96e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" "unprognostic (4.04e-3)" 1.3 0.5 28.1 0.2 34.7 1.4 2.0 24.9 39.0 0.8 20.8 0.7 0.1 0.5 0.2 0.5 0.7 0.7 1.0 28.2 27.0 1.0 1.0 0.7 0.2 34.0 29.8 0.6 0.5 0.0 1.6 0.2 33.1 0.8 0.3 1.1 9.6 0.3 2.6 2.1 0.7 0.3 28.5 0.8 0.8 2.1 32.1 0.3 0.6 0.5 0.3 0.7 1.0 50.6 0.2 0.3 2.0 1.1 0.2 0.1 0.3 0.5 0.2 0.3 0.4 1.1 3.2 0.1 1.4 0.2 0.3 0.4 0.1 0.2 0.1 0.2 0.6 0.4 0.3 0.0 0.1 0.5 0.4 0.2 0.2 0.2 0.5 0.2 0.3 0.7 0.4 0.2 0.4 0.0 0.4 0.6 0.2 2.0 0.1 0.4 0.2 0.0 0.3 0.2 0.3 0.4 0.2 0.0 1.6 0.2 0.2 0.2 0.2 0.4 0.7 0.3 0.3 0.2 0.1 0.0 0.1 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 34.7 24.9 39.0 28.2 27.0 34.0 29.8 33.1 28.5 32.1 50.6 0.2 0.0 0.0 26.4 0.2 0.3 0.2 0.0 0.0 0.5 1.0 0.9 0.5 0.0 0.1 1.8 2.1 0.0 0.2 0.2 0.0 0.3 0.1 0.3 0.2 0.3 0.0 1.3 5.4 0.9 0.0 0.3 0.0 0.4 0.0 0.4 0.4 0.2 0.1 5.0 2.8 0.0 0.0 0.0 0.3 0.3 0.3 0.1 0.0 2.8 0.1 3.2 0.0 3.5 15.5 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.1 1.3 0.0 0.5 0.1 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 TMTC1 "ARG99, FLJ31400, FLJ41625, OLF" ENSG00000133687 "Transmembrane O-mannosyltransferase targeting cadherins 1" Q8IUR5 12 29500840-29784759 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Astrocytes: 64.6;Excitatory neurons: 186.0;Inhibitory neurons: 200.5;Skeletal myocytes: 60.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 83.0;HSkMC: 56.9;hTERT-HME1: 103.8;LHCN-M2: 58.8;RH-30: 122.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016720 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA016720: AB_1858155" "unprognostic (1.67e-1)" "unprognostic (6.35e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.63e-3)" "unprognostic (4.53e-2)" "unprognostic (3.88e-2)" "unprognostic (8.36e-2)" "unprognostic (1.77e-1)" "unprognostic (8.90e-3)" "unprognostic (3.08e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (5.49e-4)" "unprognostic (5.89e-3)" "unprognostic (6.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.51e-3)" 36.7 14.1 14.5 5.2 21.0 0.2 16.8 6.7 13.5 11.9 13.3 11.9 3.1 9.0 3.0 6.8 14.3 7.1 16.5 20.0 25.0 14.7 2.4 8.7 2.7 11.4 24.0 9.3 2.6 28.0 10.7 2.8 15.8 6.9 5.9 2.6 4.5 8.8 18.5 4.0 6.4 13.2 7.9 42.4 8.3 2.4 25.1 6.9 4.7 31.2 2.1 12.1 8.2 6.3 0.0 0.0 15.3 0.0 47.7 31.6 0.1 14.7 33.1 4.3 3.4 0.0 0.2 0.1 7.4 10.0 17.6 0.0 0.5 0.2 0.2 0.3 4.6 0.0 41.5 0.7 83.0 2.1 0.0 56.9 5.6 40.3 103.8 12.2 2.2 0.0 0.0 2.2 58.8 0.0 0.0 0.0 11.1 0.2 20.8 0.0 122.4 2.1 0.0 0.3 1.2 1.2 1.7 0.0 4.1 5.4 0.0 0.8 6.2 3.7 2.4 2.3 12.5 19.6 0.0 0.0 27.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 14.5 21.0 6.7 13.5 20.0 25.0 11.4 24.0 15.8 7.9 25.1 6.3 105.0 3.2 0.6 64.6 0.9 3.3 1.0 6.1 11.4 12.1 1.3 10.4 32.3 0.0 2.4 3.7 0.0 0.1 0.0 0.0 0.0 0.1 29.6 7.7 16.2 57.9 0.0 0.0 186.0 0.0 0.0 17.5 2.0 7.0 0.0 4.3 54.7 5.4 0.5 0.0 200.5 0.2 0.0 17.7 4.2 7.5 8.1 4.9 10.6 30.9 0.5 0.5 0.0 9.5 5.7 0.0 0.0 18.4 0.3 4.0 0.1 0.7 6.0 1.3 46.0 60.3 24.9 2.4 1.7 1.3 2.0 1.9 1.0 21.9 0.0 0.4 TMTC3 "FLJ90492, SMILE" ENSG00000139324 "Transmembrane O-mannosyltransferase targeting cadherins 3" Q6ZXV5 12 88142296-88199887 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transferase "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038550 Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA038550: AB_10672715" "unprognostic (1.05e-1)" "unprognostic (6.16e-2)" "unprognostic (1.50e-2)" "unprognostic (1.18e-2)" "unprognostic (1.90e-1)" "unprognostic (5.28e-2)" "unprognostic (3.62e-3)" "unprognostic (1.71e-2)" "unprognostic (1.46e-1)" "unprognostic (4.44e-1)" "unprognostic (8.07e-3)" "unprognostic (2.56e-2)" "unprognostic (2.28e-1)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" 5.9 4.4 3.6 3.8 3.8 1.7 6.7 5.8 4.7 5.6 2.1 4.5 5.4 6.4 5.2 9.1 3.9 5.7 3.8 3.9 4.6 8.1 9.0 5.2 2.9 3.4 3.9 5.3 3.2 6.2 2.8 10.2 4.1 7.4 4.7 7.9 3.8 6.3 1.7 12.5 4.4 9.2 3.2 3.9 3.8 4.1 3.6 4.0 6.3 4.3 4.5 6.8 4.7 4.1 13.2 14.0 12.6 11.9 28.8 25.4 22.5 28.1 26.6 15.8 16.9 20.3 9.2 4.1 5.0 25.8 9.6 28.9 13.5 22.4 26.5 2.4 10.2 4.0 9.5 9.3 15.0 4.3 2.5 21.7 12.0 30.5 12.0 16.2 24.9 3.4 8.9 1.4 17.8 7.9 3.0 5.5 9.7 5.0 7.3 2.6 27.4 4.1 13.7 21.3 10.7 10.6 22.8 16.1 7.3 13.3 25.9 4.3 26.4 21.8 12.0 19.4 13.7 4.5 6.3 4.7 6.8 5.0 16.5 7.4 1.3 2.3 1.8 1.1 2.2 2.3 2.0 1.4 0.9 1.8 2.4 2.0 1.3 1.2 1.6 0.9 1.7 0.7 3.6 3.8 5.8 4.7 3.9 4.6 3.4 3.9 4.1 3.2 3.6 4.1 15.9 12.8 8.2 19.6 6.9 34.2 24.4 29.1 24.5 12.5 11.4 8.1 11.1 5.7 20.0 7.3 27.1 29.6 3.5 6.7 3.9 14.5 26.8 23.7 22.2 16.9 3.6 9.5 51.6 10.8 18.2 23.8 8.6 21.9 9.5 12.4 15.7 19.2 8.2 13.5 46.8 5.9 75.3 5.9 6.0 18.2 20.2 3.7 8.8 20.6 2.8 8.3 2.1 28.1 42.4 12.4 4.9 19.5 4.6 18.0 7.3 13.9 34.9 23.4 19.7 17.1 22.3 12.0 8.7 32.6 40.5 17.8 5.2 14.1 7.1 14.4 TNFAIP8L3 FLJ41287 ENSG00000183578 "TNF alpha induced protein 8 like 3" Q5GJ75 15 51056598-51105276 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 86.9;smooth muscle: 84.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 10.3;Inhibitory neurons: 14.4;Langerhans cells: 10.8;Smooth muscle cells: 9.3;Spermatocytes: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;ASC TERT1: 87.8;HUVEC TERT2: 78.7;LHCN-M2: 74.5;TIME: 105.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077484 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA077484: AB_2732347" "unprognostic (1.38e-1)" "unprognostic (6.22e-2)" "unprognostic (1.12e-3)" "unprognostic (6.63e-2)" "unprognostic (2.54e-1)" "unprognostic (1.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-2)" "unprognostic (4.21e-2)" "unprognostic (4.70e-3)" "unprognostic (6.54e-2)" "unprognostic (9.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (3.51e-4)" 9.4 3.8 9.2 7.1 8.3 0.8 5.7 3.5 8.2 13.7 4.3 8.6 1.6 86.9 6.0 20.4 45.6 6.2 6.3 15.3 6.6 2.7 2.4 15.5 3.9 5.5 8.5 15.9 2.4 0.8 3.0 2.0 4.8 6.8 8.6 0.3 3.9 5.4 4.7 23.1 7.9 84.8 4.3 19.9 5.8 4.4 6.6 0.9 5.4 3.5 3.2 18.6 15.1 5.6 0.1 0.4 0.1 0.2 35.0 87.8 0.4 0.3 0.1 1.0 1.6 0.1 1.0 0.1 1.5 5.0 11.2 0.1 1.2 0.8 0.4 0.1 0.7 0.0 2.4 5.9 9.1 0.3 1.9 32.5 7.1 6.7 26.8 5.8 78.7 0.1 0.1 0.1 74.5 0.9 0.0 0.6 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.1 0.1 0.1 0.9 0.5 0.6 105.5 8.0 0.5 26.5 2.3 0.4 0.0 0.1 16.7 0.1 0.1 0.9 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.6 0.3 0.2 0.2 0.0 0.0 9.2 8.3 3.5 8.2 15.3 6.6 5.5 8.5 4.8 4.3 6.6 5.6 1.2 0.0 0.5 4.6 0.0 3.3 1.1 0.4 0.0 0.1 0.2 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.3 2.3 1.7 3.9 10.3 0.0 4.5 0.4 0.0 5.8 0.0 0.1 0.0 7.1 1.8 0.3 2.9 0.0 14.4 3.3 2.0 2.9 10.8 0.7 9.0 3.5 1.8 1.0 0.6 0.1 0.0 1.0 2.6 0.1 1.5 5.3 0.1 0.4 0.0 0.1 1.3 0.2 6.6 1.6 9.3 23.7 0.8 0.3 8.4 0.0 0.1 0.1 1.5 0.5 TNFRSF18 "AITR, CD357, GITR" ENSG00000186891 "TNF receptor superfamily member 18" Q9Y5U5 1 1203508-1206592 "CD markers, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 189.0;dendritic cells: 72.2;Langerhans cells: 86.4;Melanocytes: 49.8;Plasma cells: 55.3;Suprabasal keratinocytes: 150.6;T-cells: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cell: 184.5;T-reg: 71.8" "Group enriched" "Detected in many" 11 "NK-cells: 184.5;T-cells: 71.8" "Group enriched" "Detected in some" 12 "RPMI-8226: 225.6;SCLC-21H: 152.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008025 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA008025: AB_1849696" "unprognostic (1.20e-3)" "unprognostic (4.61e-2)" "unprognostic (4.59e-2)" "prognostic favorable (7.72e-6)" "unprognostic (2.73e-4)" "prognostic favorable (4.12e-4)" "unprognostic (3.43e-2)" "unprognostic (2.31e-1)" "unprognostic (3.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.00e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.40e-11)" "unprognostic (1.02e-3)" "unprognostic (2.39e-1)" "unprognostic (3.74e-1)" "unprognostic (2.08e-1)" 1.9 0.6 1.1 7.3 1.3 2.9 2.4 2.5 3.1 11.1 0.7 6.0 7.2 1.4 0.0 6.3 1.4 0.9 0.5 1.0 0.6 2.8 0.9 4.6 5.5 1.3 0.6 0.3 0.3 9.4 4.9 0.3 1.3 2.8 1.5 0.0 5.6 0.6 0.8 38.5 7.1 0.3 0.6 9.0 5.2 0.9 0.9 1.9 1.4 0.0 3.8 2.0 3.3 1.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.3 1.2 0.1 0.5 16.1 0.1 0.1 225.6 0.3 0.0 152.8 0.2 0.0 0.6 0.0 0.0 8.2 0.1 0.0 0.0 0.3 0.2 0.0 0.9 0.3 0.2 0.6 0.1 0.0 0.2 0.2 0.0 6.8 0.1 12.6 4.6 28.9 4.4 0.1 11.5 0.9 1.5 0.8 184.5 0.1 0.3 71.8 6.7 1.1 1.3 2.5 3.1 1.0 0.6 1.3 0.6 1.3 0.6 0.9 1.2 11.2 0.0 1.3 0.3 23.5 189.0 12.5 15.5 16.5 0.0 5.0 3.0 2.9 0.0 3.2 0.0 0.0 0.0 72.2 0.3 0.0 0.8 0.0 1.2 1.2 4.1 3.5 0.0 2.0 0.6 1.3 4.7 1.1 2.9 45.7 0.0 0.7 0.0 0.8 0.0 0.3 0.2 20.3 0.3 86.4 0.0 0.0 5.4 49.8 0.0 12.7 0.0 21.6 0.5 0.3 0.4 0.0 0.0 55.3 10.1 0.1 0.1 0.8 0.0 0.0 6.2 2.2 0.0 0.0 0.3 150.6 0.0 75.7 0.0 0.8 7.0 TNFRSF19 "TAJ, TAJ-alpha, TRADE, TROY" ENSG00000127863 "TNF receptor superfamily member 19" Q9NS68 13 23570370-23676104 "Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 55.3;skin 1: 107.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 62.2;Microglial cells: 71.2;Respiratory ciliated cells: 62.4;Suprabasal keratinocytes: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.5;BJ hTERT+: 73.2;fHDF/TERT166: 55.9;Hep G2: 83.0;SK-MEL-30: 128.4;WM-115: 76.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010135 Approved Nucleoplasm,Mitochondria No No "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 28: Keratinocytes - Keratinization" Mitochondria Nucleoplasm "HPA010135: AB_1079797" "unprognostic (5.70e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.86e-3)" "unprognostic (2.01e-2)" "prognostic favorable (3.87e-4)" "unprognostic (3.74e-1)" "unprognostic (5.47e-2)" "unprognostic (4.41e-2)" "unprognostic (6.56e-2)" "prognostic favorable (9.13e-7)" "unprognostic (3.44e-2)" "unprognostic (6.05e-2)" "unprognostic (3.25e-3)" "unprognostic (5.38e-3)" 1.8 2.9 1.8 0.9 1.7 1.7 9.9 1.8 1.9 7.0 4.2 2.4 1.8 8.6 13.4 9.4 30.5 3.4 22.1 2.0 2.5 15.7 1.1 17.2 0.7 3.3 3.2 2.7 2.8 0.9 8.5 8.4 2.6 27.4 1.9 4.7 55.3 7.6 2.4 107.5 1.3 3.0 3.1 5.1 5.4 2.2 2.7 6.7 3.4 2.1 1.8 4.5 4.8 2.5 0.1 3.3 3.2 0.0 4.7 46.5 3.5 3.7 73.2 2.0 2.8 23.6 0.1 0.0 0.0 55.9 0.5 0.1 3.3 2.9 3.6 0.0 2.9 0.6 2.4 83.0 2.2 0.2 0.9 22.5 0.7 23.1 0.3 1.5 0.1 0.0 0.1 0.0 13.2 1.1 0.0 0.1 2.3 29.7 5.1 0.0 13.6 0.0 8.4 0.4 30.9 4.9 0.1 0.0 128.4 3.4 0.0 0.3 0.0 11.5 0.5 0.1 3.5 0.0 0.1 0.0 4.5 0.1 76.2 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 1.8 1.7 1.8 1.9 2.0 2.5 3.3 3.2 2.6 3.1 2.7 2.5 3.1 0.0 20.8 1.0 0.2 62.2 3.0 2.0 23.9 0.8 6.3 2.9 23.4 2.8 9.3 9.2 8.4 0.1 0.3 0.1 0.0 11.1 1.7 10.4 4.4 5.1 0.0 0.0 6.9 1.0 0.0 14.4 2.6 3.9 1.3 0.5 0.0 0.5 0.1 0.0 6.7 0.0 6.1 0.0 8.5 1.0 11.5 0.2 14.2 71.2 0.0 3.3 0.0 12.5 1.1 11.3 0.0 13.9 0.0 13.3 0.0 20.9 62.4 3.3 0.0 3.2 4.9 1.5 2.3 8.3 80.3 0.0 0.6 3.5 0.0 0.6 TNKS1BP1 "FLJ45975, KIAA1741, TAB182" ENSG00000149115 "Tankyrase 1 binding protein 1" Q9C0C2 11 57299638-57324952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037929, HPA037930" Enhanced Uncertain "Plasma membrane" NA NA 180000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA037929: AB_10672613, HPA037930: AB_2675745" "unprognostic (7.31e-2)" "unprognostic (1.66e-2)" "unprognostic (5.38e-2)" "unprognostic (2.25e-1)" "unprognostic (3.13e-1)" "unprognostic (9.17e-2)" "unprognostic (2.47e-2)" "unprognostic (7.90e-2)" "unprognostic (4.27e-1)" "unprognostic (2.67e-2)" "unprognostic (4.22e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (2.11e-8)" "unprognostic (2.46e-1)" "unprognostic (2.31e-2)" "unprognostic (2.41e-1)" "unprognostic (3.07e-1)" 62.7 27.3 11.8 17.3 10.2 3.3 41.9 4.6 9.4 43.3 18.0 23.6 28.8 40.3 30.3 55.4 35.3 28.1 23.3 11.3 9.2 14.7 31.6 40.3 6.6 9.6 8.8 32.2 30.9 18.9 17.1 29.5 7.2 33.6 16.2 3.3 44.2 40.2 67.2 83.0 26.6 29.4 4.9 18.1 52.8 10.1 11.0 22.3 25.0 29.9 14.3 38.5 45.6 6.7 89.5 58.7 41.2 33.6 127.8 97.1 31.0 61.5 113.8 46.3 42.5 26.1 59.5 2.0 38.5 101.2 49.6 151.7 31.4 105.3 30.1 34.2 10.4 11.5 38.2 12.2 86.6 14.4 4.3 96.8 123.5 70.9 54.6 57.5 60.0 12.4 13.2 9.3 65.3 45.4 11.0 14.7 45.8 46.5 45.9 16.9 57.2 25.9 53.5 116.6 14.6 22.6 81.5 121.5 44.3 29.0 182.2 11.9 115.1 47.3 45.8 56.6 35.2 15.0 4.1 11.3 107.0 4.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.8 10.2 4.6 9.4 11.3 9.2 9.6 8.8 7.2 4.9 11.0 6.7 38.1 12.8 35.4 12.7 1.9 83.6 28.0 61.9 40.9 4.8 24.8 23.9 7.9 38.6 39.0 44.1 2.1 16.8 1.3 27.3 0.0 31.8 1.8 18.5 25.4 25.9 18.0 7.4 7.2 22.3 3.2 31.2 49.5 38.4 2.5 3.7 19.6 46.0 3.9 8.4 4.8 25.8 18.3 1.5 25.4 2.9 48.1 3.8 17.8 1.9 0.7 4.0 0.0 4.5 2.4 38.8 14.3 49.2 0.6 41.2 18.2 2.4 15.4 1.3 32.9 41.2 26.9 1.5 3.0 68.9 88.2 24.5 2.3 23.4 14.5 36.8 TNN TNW ENSG00000120332 "Tenascin N" Q9UQP3 1 175067833-175148075 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 12.0;breast: 4.9" "Cell type enhanced" "Detected in some" "Adipocytes: 6.1;Fibroblasts: 7.5;Hepatic stellate cells: 2.5;Langerhans cells: 2.5;Smooth muscle cells: 10.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.6;NB-4: 3.6;THP-1: 11.1;U-266/70: 2.7;U-937: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB010907, HPA026726, HPA026764" Uncertain "Secreted to extracellular matrix" NA NA 34000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010907: AB_477565, HPA026726: AB_10601771, HPA026764: AB_10601859" "unprognostic (1.16e-3)" "unprognostic (2.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-2)" "unprognostic (1.34e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (3.55e-1)" "unprognostic (5.25e-3)" "unprognostic (1.01e-2)" "unprognostic (4.69e-1)" "unprognostic (5.07e-1)" "unprognostic (1.08e-3)" "unprognostic (1.76e-2)" "unprognostic (9.38e-3)" "unprognostic (1.89e-2)" "unprognostic (1.02e-2)" 12.0 0.2 0.0 0.1 0.1 0.0 4.9 0.0 0.1 0.1 0.1 0.3 0.8 0.0 0.0 0.1 0.0 1.7 0.3 0.2 0.0 0.4 1.3 0.4 0.1 0.0 0.1 0.0 0.3 0.8 2.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 3.1 0.4 0.4 0.1 0.4 0.4 0.1 0.1 0.1 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 11.1 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 6.1 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.0 0.7 0.0 0.1 7.5 0.0 0.1 0.0 0.0 2.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 10.4 0.4 1.4 0.0 1.8 0.1 0.1 0.0 0.0 0.1 TNNC1 TNNC ENSG00000114854 "Troponin C1, slow skeletal and cardiac type" P63316 3 52451100-52454041 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 36 "heart muscle: 8734.3;skeletal muscle: 21081.1;tongue: 12403.9" "Cell type enriched" "Detected in many" 10 "Cardiomyocytes: 3550.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 27.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 6 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "CACO-2: 68.2;CAPAN-2: 33.5;EFO-21: 65.2;HeLa: 49.1;Hep G2: 46.1;HSkMC: 67.2;U-2 OS: 97.7" "Region enriched" "Detected in all" 4 "cerebral cortex: 87.0" "Group enriched" "Detected in some" 6 "midbrain: 7.6;spinal cord: 7.1" "CAB002450, HPA044848, HPA056897" Enhanced Approved "Nucleoplasm,Actin filaments,Mitochondria" NA NA 990000 "Cluster 13: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Actin filaments, Mitochondria" "CAB002450: AB_564152, HPA044848: AB_2679110, HPA056897: AB_2683269" "unprognostic (2.18e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (3.43e-1)" "unprognostic (4.00e-2)" "unprognostic (1.88e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (2.15e-2)" "unprognostic (4.95e-2)" "unprognostic (2.31e-1)" "unprognostic (4.15e-2)" "unprognostic (4.86e-1)" 8.4 10.9 0.7 0.8 0.8 0.7 19.1 2.7 1.1 7.7 7.3 4.0 1.1 2.8 41.7 387.3 2.8 3.3 8734.3 1.2 0.7 19.2 4.0 78.5 3.9 0.8 0.9 2.4 6.8 1.6 17.6 5.2 1.0 170.1 4.1 0.4 120.8 2.2 21081.1 18.9 3.3 0.8 0.8 2.8 5.7 10.6 0.8 4.3 14.4 12403.9 1.6 5.3 5.4 0.7 0.7 5.2 3.6 0.6 0.2 0.5 8.0 0.4 0.3 0.3 0.4 68.2 33.5 0.5 65.2 9.9 0.1 0.4 0.1 0.3 0.0 1.2 1.6 0.5 49.1 46.1 0.3 0.3 0.1 67.2 1.2 0.0 0.7 0.6 0.0 2.0 0.2 5.1 2.0 0.1 0.2 0.8 0.5 15.1 0.7 0.1 2.9 2.3 3.3 13.0 0.2 0.0 0.5 6.7 0.1 3.9 26.7 0.5 0.0 0.1 97.7 0.8 0.2 2.8 1.3 0.9 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.8 0.1 0.7 0.8 2.7 1.1 1.2 0.7 0.8 0.9 1.0 0.8 0.8 0.7 0.2 125.0 12.6 0.0 0.3 1.5 1.7 4.0 0.6 0.2 0.5 0.3 3550.1 5.7 7.9 3.7 2.1 59.0 0.1 1.6 27.4 11.8 0.7 66.4 6.7 39.8 330.7 0.4 0.0 13.0 5.1 52.7 0.5 98.8 0.0 0.8 0.7 0.7 4.9 0.0 0.0 1.7 2.0 0.0 1.4 5.8 22.4 2.6 5.4 0.0 0.1 1.2 0.0 0.0 0.0 6.5 0.3 177.6 0.1 0.8 0.5 1.3 2.8 0.1 0.0 241.8 36.0 2.1 1.0 0.1 0.9 31.1 2.8 1.3 2.0 6.8 TNNT1 "ANM, FLJ98147, MGC104241, NEM5, STNT, TNT, TNTS" ENSG00000105048 "Troponin T1, slow skeletal type" P13805 19 55132698-55149206 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 29 "skeletal muscle: 21567.3;tongue: 13372.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 61.2;Basal squamous epithelial cells: 47.8;Cardiomyocytes: 51.5;Skeletal myocytes: 192.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "eosinophil: 211.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 211.5" "Cell line enhanced" "Detected in many" "HMC-1: 829.4;RH-30: 638.8" "Region enriched" "Detected in many" 5 "thalamus: 125.0" "Region enhanced" "Detected in all" "thalamus: 23.1" "CAB015168, HPA058448" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 79000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Golgi apparatus, Cytosol" "CAB015168: AB_2206426, HPA058448: AB_2683720" "unprognostic (1.88e-1)" "unprognostic (7.23e-2)" "prognostic unfavorable (4.66e-4)" "prognostic unfavorable (4.66e-4)" "unprognostic (3.47e-3)" "unprognostic (3.92e-3)" "unprognostic (1.35e-3)" "unprognostic (1.03e-3)" "unprognostic (2.46e-1)" "unprognostic (1.95e-1)" "prognostic unfavorable (2.53e-4)" "unprognostic (3.23e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.91e-2)" "unprognostic (4.01e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-2)" 5.7 1.2 42.1 0.4 45.7 3.3 5.0 44.3 55.4 1.9 36.4 2.7 1.0 1.1 1.0 593.5 8.4 1.0 256.7 43.9 38.9 1.3 2.5 8.3 0.4 36.7 41.4 1.5 2.5 2.3 8.5 6.0 38.5 200.4 0.6 0.6 171.2 0.4 21567.3 48.5 2.0 0.4 35.6 1.9 1.9 10.6 40.8 3.4 3.8 13372.6 2.0 1.7 5.8 40.8 178.4 102.3 1.0 22.4 0.0 1.7 33.3 8.0 30.1 11.1 32.7 37.9 115.8 2.6 66.5 3.2 88.8 88.5 24.0 76.0 9.4 11.8 192.2 33.6 11.8 6.7 3.7 2.7 829.4 36.6 121.3 3.4 127.0 125.7 0.5 35.1 171.7 158.6 10.3 168.0 3.4 0.3 21.4 45.0 202.1 113.9 638.8 21.2 26.5 5.8 6.6 49.3 10.7 1.3 57.9 8.5 106.3 102.7 2.9 163.6 238.9 6.5 12.4 1.2 7.0 8.8 171.8 26.4 50.9 2.4 39.4 211.5 0.3 21.7 0.3 0.2 0.3 0.3 37.4 0.4 0.3 0.4 1.9 0.6 10.2 0.9 0.1 12.2 42.1 45.7 44.3 55.4 43.9 38.9 36.7 41.4 38.5 35.6 40.8 40.8 0.0 0.0 0.0 0.7 0.3 61.2 0.6 25.1 47.8 4.5 0.5 5.3 51.5 0.0 2.8 0.0 0.0 2.2 0.0 0.5 0.0 2.1 2.1 9.7 0.3 2.6 2.4 2.7 0.4 0.0 18.0 18.8 0.0 3.4 0.0 22.1 1.4 0.0 12.9 0.0 0.7 0.3 0.0 13.2 3.8 10.7 0.3 8.9 3.6 0.0 25.8 0.7 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.7 0.0 192.0 3.5 4.3 34.1 2.5 30.4 3.6 1.6 1.2 0.8 0.2 TNXB "TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 274.8" "Cell type enhanced" "Detected in many" "Adipocytes: 54.7;Fibroblasts: 318.4;Granulosa cells: 94.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 12.4;ASC TERT1: 20.1;U-2197: 15.8;U-87 MG: 8.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" 68.0 274.8 2.0 0.9 3.1 3.4 40.0 4.4 1.8 45.1 3.5 35.9 3.0 66.7 3.2 18.1 37.4 4.7 73.8 0.7 0.8 13.0 17.6 51.1 0.8 1.5 1.1 67.0 3.7 0.4 6.8 3.8 1.5 15.6 1.7 0.3 19.5 1.0 14.2 27.4 29.0 3.1 2.2 30.7 18.8 11.4 3.0 0.7 27.7 7.2 0.4 34.5 35.2 0.4 0.1 0.3 0.3 0.2 12.4 20.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.4 1.2 0.0 0.1 0.0 0.0 0.1 1.3 1.1 0.2 0.6 0.0 2.8 0.0 0.3 0.2 0.2 0.5 0.0 0.5 0.0 0.5 0.7 0.4 0.0 0.2 0.0 0.1 0.3 0.0 3.5 0.3 0.1 0.2 0.0 0.1 0.1 0.2 1.3 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.4 15.8 0.0 0.4 0.4 0.2 8.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 3.1 4.4 1.8 0.7 0.8 1.5 1.1 1.5 2.2 3.0 0.4 54.7 3.2 2.4 2.6 0.5 32.9 0.2 0.3 0.6 1.3 1.3 1.8 2.5 4.3 0.2 0.0 0.0 0.5 1.0 0.0 0.0 0.2 3.0 1.3 39.7 38.8 0.0 25.0 7.1 0.0 2.6 318.4 6.1 1.1 0.0 94.8 12.8 0.9 0.7 0.0 4.2 0.1 0.0 0.6 39.1 2.8 27.1 4.7 32.0 17.8 0.0 1.2 0.0 1.0 1.2 0.0 0.1 4.5 2.5 0.5 0.0 0.3 0.9 0.6 0.0 21.7 20.8 4.1 2.1 1.6 26.6 1.0 4.8 5.6 0.2 0.4 TOLLIP IL-1RAcPIP ENSG00000078902 "Toll interacting protein" Q9H0E2 11 1274371-1309654 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 498.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038621, HPA038622" Enhanced Approved Cytosol NA NA 140000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA038621: AB_10673177, HPA038622: AB_10675946" "unprognostic (8.39e-2)" "unprognostic (1.89e-1)" "unprognostic (2.18e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (8.89e-2)" "unprognostic (2.51e-1)" "unprognostic (8.53e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.11e-16)" "unprognostic (2.72e-1)" "unprognostic (1.46e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-2)" 26.8 35.4 58.2 12.4 73.5 13.6 25.8 27.5 80.9 35.9 17.6 26.3 25.5 23.5 11.5 93.4 22.4 18.4 31.3 85.0 39.4 43.1 113.3 26.6 14.2 39.9 39.1 24.6 58.2 18.9 54.2 12.1 39.8 31.4 8.2 11.4 31.6 20.5 76.2 75.9 23.4 11.1 32.9 28.8 31.9 73.4 42.7 13.2 24.7 22.7 14.2 33.5 48.8 56.5 31.4 32.6 16.3 18.6 34.0 21.2 14.2 27.2 24.5 31.3 27.7 35.4 19.5 14.6 25.6 25.3 47.9 27.7 14.7 33.4 8.5 30.1 30.1 11.9 6.9 54.2 48.4 22.8 29.0 32.1 38.5 18.6 17.9 17.1 19.7 21.7 19.9 38.5 26.1 26.3 29.1 27.9 20.0 33.9 42.1 21.8 16.6 14.6 20.9 41.3 43.5 25.5 24.4 29.4 30.7 8.3 23.3 25.7 36.0 33.8 14.4 14.4 16.0 38.8 37.8 18.3 53.2 14.9 27.0 45.4 126.6 139.6 33.4 114.0 27.8 38.8 35.3 31.5 99.9 50.0 27.4 26.1 179.1 44.5 108.8 52.4 48.8 77.3 58.2 73.5 27.5 80.9 85.0 39.4 39.9 39.1 39.8 32.9 42.7 56.5 19.5 9.6 19.3 15.0 27.8 66.9 43.9 71.7 23.3 42.6 30.3 24.6 22.8 58.6 30.9 23.9 8.4 49.2 28.0 50.8 70.5 66.3 173.6 11.7 14.8 24.9 51.6 45.0 35.1 69.2 41.1 27.6 19.4 15.8 38.1 20.7 37.9 112.2 92.1 74.0 17.0 30.8 48.8 38.4 33.1 498.2 21.8 48.3 71.2 16.9 50.6 38.1 19.6 10.6 15.0 76.3 53.7 30.9 33.4 55.7 66.6 110.1 15.4 20.6 6.6 18.5 24.5 100.7 39.6 76.3 98.9 104.4 22.0 27.4 29.3 74.0 TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347992 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 213.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 170.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000818, HPA001749" Approved Approved "Plasma membrane,Centriolar satellite,Cytosol" NA NA 44000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane, Centriolar satellite" "HPA000818: AB_2666101, HPA001749: AB_1080323" "unprognostic (3.75e-1)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.11e-2)" "unprognostic (7.55e-2)" "unprognostic (4.07e-3)" "unprognostic (2.24e-1)" "unprognostic (9.92e-2)" "unprognostic (2.32e-1)" "unprognostic (3.71e-1)" "unprognostic (8.16e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" "unprognostic (7.54e-3)" "unprognostic (3.31e-2)" 34.7 47.8 20.8 17.0 19.4 60.8 32.1 19.9 25.8 43.6 23.6 22.7 29.1 26.6 12.7 76.5 26.8 24.9 43.2 19.8 26.6 32.7 49.0 37.1 15.3 30.2 24.5 21.5 20.2 48.5 37.4 27.7 32.9 23.2 9.8 5.9 60.6 11.7 213.8 74.9 28.4 10.8 19.6 23.9 20.8 25.9 24.8 13.1 26.5 68.6 12.7 19.5 45.0 22.1 15.8 15.3 8.8 14.3 58.3 34.9 42.3 15.5 43.8 28.4 31.1 21.5 14.3 6.2 28.0 45.4 18.3 7.3 8.6 15.6 9.9 18.7 21.3 5.3 17.1 43.8 58.6 10.8 23.6 49.8 19.2 39.6 13.3 18.5 19.8 11.6 10.3 15.3 14.1 13.8 8.2 27.5 7.0 18.9 8.6 14.9 12.3 13.2 10.9 11.3 14.9 12.1 34.1 34.8 34.5 7.3 18.0 16.7 22.0 34.0 29.4 27.3 7.7 18.0 12.4 16.7 45.7 10.5 11.4 18.6 100.9 44.5 19.3 60.7 15.6 13.6 29.5 18.4 48.0 11.0 22.6 15.7 129.1 15.1 66.2 25.9 48.2 63.3 20.8 19.4 19.9 25.8 19.8 26.6 30.2 24.5 32.9 19.6 24.8 22.1 10.1 22.4 36.9 8.8 12.7 12.7 10.3 29.5 7.4 11.1 19.1 11.0 23.2 15.7 33.0 12.9 12.5 64.6 13.8 41.6 27.4 40.9 29.9 32.0 17.8 14.2 16.2 9.7 9.3 38.9 57.1 22.6 15.3 48.0 22.8 10.4 16.1 34.0 60.8 11.8 15.2 18.1 50.8 33.5 35.2 21.4 11.5 45.2 19.6 7.5 34.0 19.5 9.2 6.6 13.2 34.2 21.5 12.8 5.7 11.9 55.3 34.9 24.2 8.2 6.6 16.6 15.4 23.5 5.6 17.3 21.9 170.2 18.2 13.4 15.2 10.7 TOM1L2 ENSG00000175662 "Target of myb1 like 2 membrane trafficking protein" Q6ZVM7 17 17843511-17972422 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 180.5;Cone photoreceptor cells: 158.4;Oligodendrocytes: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022541, HPA023304" Enhanced Approved "Golgi apparatus,Intermediate filaments" NA NA 73000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Intermediate filaments" "Golgi apparatus" "HPA022541: AB_1858182, HPA023304: AB_1858183" "unprognostic (2.32e-1)" "unprognostic (7.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.57e-2)" "unprognostic (3.25e-2)" "prognostic favorable (1.24e-4)" "unprognostic (2.22e-1)" "unprognostic (1.08e-1)" "unprognostic (6.29e-2)" "prognostic unfavorable (2.58e-4)" "prognostic favorable (1.92e-4)" "unprognostic (3.19e-2)" "prognostic favorable (6.21e-9)" "unprognostic (7.11e-2)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (4.51e-2)" 20.7 30.5 64.0 9.5 62.7 6.1 20.3 52.7 70.0 31.9 21.3 44.2 14.0 33.2 11.0 64.4 26.6 13.0 141.0 66.0 56.4 31.3 13.9 23.2 7.7 91.5 80.3 32.9 19.7 40.3 42.2 9.0 95.3 37.3 13.8 50.2 21.3 28.7 67.1 59.7 20.9 23.3 49.7 16.6 34.9 39.4 74.6 8.8 48.5 55.4 12.9 31.4 35.1 72.7 27.1 29.0 8.2 6.2 19.1 19.3 14.2 43.3 20.1 22.9 19.3 28.2 17.6 5.0 52.9 40.8 13.3 104.3 6.8 24.1 14.0 7.2 12.7 8.0 28.0 6.0 12.2 2.0 5.2 22.9 16.6 20.5 15.2 19.6 23.3 7.3 3.0 6.9 30.3 27.1 3.6 4.6 1.5 34.4 19.5 4.7 20.7 12.0 32.4 48.1 8.7 8.4 19.5 25.2 15.3 55.9 13.4 3.6 31.8 21.9 6.5 46.0 16.8 6.1 5.1 2.3 26.4 2.7 55.2 10.0 3.3 4.8 2.8 1.0 2.0 1.6 2.6 2.4 1.6 2.2 4.3 3.2 12.8 1.4 3.3 1.9 1.3 1.7 64.0 62.7 52.7 70.0 66.0 56.4 91.5 80.3 95.3 49.7 74.6 72.7 10.1 32.1 17.0 180.5 9.5 10.8 14.6 13.9 7.4 74.5 20.9 14.1 73.7 15.7 16.6 11.0 158.4 8.5 10.2 43.3 5.9 12.2 30.8 14.1 9.4 12.4 20.4 4.8 63.2 8.7 17.4 12.7 13.3 15.7 2.5 28.1 16.4 13.4 9.2 95.9 74.2 19.2 18.3 8.5 7.6 64.2 26.4 6.4 12.4 35.6 11.8 28.1 10.3 66.9 123.2 16.1 41.0 25.6 8.4 39.1 22.4 11.1 22.9 78.3 19.7 18.0 13.0 16.7 12.1 37.2 17.2 32.2 10.0 30.8 15.4 64.5 TONSL "IKBR, NFKBIL2" ENSG00000160949 "Tonsoku like, DNA repair protein" Q96HA7 8 144428775-144444440 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 76.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024679, HPA046494" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear bodies" "HPA024679: AB_1854441, HPA046494: AB_2679673" "unprognostic (6.68e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.88e-2)" "unprognostic (7.35e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.04e-3)" "unprognostic (7.81e-2)" "unprognostic (4.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.62e-7)" "unprognostic (3.24e-2)" "unprognostic (1.78e-1)" "unprognostic (9.11e-3)" "unprognostic (7.96e-2)" 1.0 2.1 0.4 2.5 0.4 8.5 1.3 0.4 1.3 1.7 0.0 3.4 3.5 1.6 0.2 3.9 1.4 0.6 1.4 0.3 0.3 1.4 1.7 1.3 2.3 1.3 0.6 1.7 1.5 0.4 0.9 1.5 1.1 1.6 0.8 0.1 1.5 0.8 0.5 3.3 4.4 0.6 0.1 3.9 2.2 3.8 0.8 2.3 2.4 0.1 1.4 2.3 2.1 0.3 21.2 18.6 13.7 21.7 1.0 1.7 33.0 17.6 3.4 10.4 8.1 15.0 17.9 19.6 17.5 2.7 4.9 14.2 13.4 10.7 2.3 20.2 26.6 46.5 26.1 15.9 0.6 14.3 28.1 1.7 1.5 10.9 2.1 2.6 5.0 26.5 53.0 14.3 4.2 43.4 35.5 24.5 19.4 20.4 26.7 42.6 8.9 20.3 5.9 22.6 22.9 13.0 18.4 12.3 7.8 5.2 17.6 13.2 5.9 12.7 52.3 14.5 21.7 5.0 9.9 12.0 12.3 30.2 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.4 1.3 0.3 0.3 1.3 0.6 1.1 0.1 0.8 0.3 2.5 6.4 22.4 1.6 2.9 8.9 5.2 1.0 1.2 3.1 3.5 2.9 2.3 8.6 3.7 1.8 2.1 4.1 1.3 20.2 0.0 0.9 0.4 4.3 2.7 4.3 2.4 7.2 2.4 1.0 5.3 3.8 11.7 6.1 2.5 8.5 2.9 11.4 4.5 1.7 1.0 14.6 0.0 0.9 16.7 0.7 0.3 3.0 14.2 1.9 1.2 1.1 1.0 0.5 0.8 1.2 7.1 1.2 4.0 3.9 76.5 7.7 4.1 3.0 6.6 6.4 2.8 4.6 7.8 3.4 11.2 1.2 3.1 3.3 15.9 3.9 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 127.8;testis: 65.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 216.8;Granulosa cells: 117.5;Spermatocytes: 621.2;Spermatogonia: 269.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in some" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.2 2.5 0.2 20.0 0.2 42.0 5.4 0.1 0.7 5.0 1.1 17.8 18.1 3.9 0.3 29.0 1.5 2.6 1.2 0.2 0.2 1.2 2.8 4.1 40.3 0.2 0.8 1.0 0.9 0.3 0.3 15.9 0.5 1.4 19.8 0.1 4.3 0.5 0.3 15.3 17.0 7.6 0.2 9.9 8.9 65.7 1.1 127.8 1.9 0.2 42.5 6.0 9.6 0.4 212.6 275.6 343.1 158.0 16.8 33.9 76.3 283.3 151.5 255.0 224.2 130.5 157.6 339.4 140.1 96.7 152.7 326.5 266.8 113.5 339.5 182.7 177.8 224.8 167.9 216.7 1.6 318.4 228.6 7.4 9.2 179.8 181.4 55.1 136.3 216.5 247.5 225.8 279.2 72.6 372.3 209.6 143.0 152.4 108.3 310.7 531.9 141.3 61.6 133.3 201.6 144.6 229.3 281.4 89.4 198.2 236.9 143.2 90.3 167.0 233.2 195.5 276.7 128.4 154.9 290.7 94.3 214.9 285.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.3 0.3 0.1 0.1 0.0 0.0 0.1 1.4 0.1 0.0 2.4 0.4 0.2 0.2 0.1 0.7 0.2 0.2 0.2 0.8 0.5 0.2 1.1 0.4 1.0 0.0 2.0 0.3 17.4 11.7 3.7 15.0 2.2 0.0 18.7 17.1 1.3 2.8 5.8 0.0 0.0 72.9 6.1 19.8 0.0 0.8 20.3 12.7 15.8 9.3 0.0 216.8 0.2 0.0 92.4 23.3 23.0 10.0 0.0 117.5 20.7 5.4 83.5 0.0 0.1 34.2 18.3 33.9 13.2 19.1 4.7 14.1 1.8 0.0 2.6 0.0 3.1 0.0 0.1 0.3 3.5 1.9 31.3 3.1 3.4 0.1 1.8 0.0 72.3 0.5 19.5 621.2 269.6 45.1 6.1 8.9 14.8 4.3 61.0 6.9 TOX3 "CAGF9, TNRC9" ENSG00000103460 "TOX high mobility group box family member 3" O15405 16 52436417-52547802 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.9;retina: 17.6;stomach 1: 20.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 52.9;Enteroendocrine cells: 61.7;Inhibitory neurons: 138.9;Muller glia cells: 162.1;Oligodendrocyte precursor cells: 51.8;Oligodendrocytes: 75.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 46.1;HAP1: 22.1;Hep G2: 20.8;OE19: 25.8;RT4: 97.1;SCLC-21H: 30.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040240, HPA040376" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm Cytosol "HPA040240: , HPA040376: AB_10795522" "unprognostic (1.14e-2)" "unprognostic (9.75e-3)" "unprognostic (9.08e-3)" "unprognostic (3.32e-2)" "unprognostic (3.50e-1)" "unprognostic (2.31e-1)" "unprognostic (4.74e-3)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.94e-2)" "unprognostic (2.59e-1)" "unprognostic (4.60e-3)" "prognostic favorable (3.08e-12)" "unprognostic (1.19e-1)" "unprognostic (1.31e-1)" "prognostic favorable (3.95e-4)" 0.4 3.0 4.7 1.4 5.6 0.0 3.8 1.2 6.0 7.6 0.3 15.6 9.3 1.3 4.4 0.6 3.1 6.9 0.0 5.3 4.4 9.5 5.2 1.4 0.1 4.6 3.5 0.9 2.6 0.0 2.3 0.2 3.0 1.8 17.9 17.6 8.9 0.5 4.0 0.7 9.3 1.0 5.1 0.0 20.3 0.6 8.4 1.3 0.0 0.5 0.2 5.7 1.0 6.8 0.0 5.8 46.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 3.5 0.0 0.3 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 25.8 0.0 0.0 8.0 0.2 10.7 97.1 30.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 5.6 1.2 6.0 5.3 4.4 4.6 3.5 3.0 5.1 8.4 6.8 0.2 6.4 8.2 1.3 0.0 1.0 0.5 2.8 0.6 4.1 20.0 12.6 0.7 52.9 7.7 35.0 0.0 0.0 0.0 47.6 3.9 1.6 3.2 1.6 0.4 0.3 61.7 0.0 3.9 5.1 0.0 1.5 29.6 6.1 0.0 0.1 0.7 4.6 0.1 40.4 138.9 31.7 2.0 0.0 0.3 1.8 0.6 0.2 0.0 8.4 0.0 162.1 0.0 51.8 75.0 15.3 15.2 0.0 0.2 11.8 16.6 14.0 12.3 3.8 0.0 3.3 0.8 0.1 0.8 0.3 0.3 0.0 0.4 9.7 32.6 6.5 TP63 "EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 69.6;skin 1: 137.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 275.4;Basal squamous epithelial cells: 335.2;Squamous epithelial cells: 173.4;Suprabasal keratinocytes: 283.1" "Group enriched" "Detected in many" 11 "cervical cancer: 37.9;head and neck cancer: 73.3;lung cancer: 37.3;urothelial cancer: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 87.1;HBEC3-KT: 167.3;hTCEpi: 124.0;hTERT-HME1: 117.3;RT4: 185.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000083: AB_2207187, HPA006288: AB_1080334, HPA006289: , HPA007009: , HPA007010: AB_1080336" "prognostic favorable (1.07e-4)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (3.02e-1)" "unprognostic (4.38e-2)" "unprognostic (3.50e-1)" "unprognostic (1.29e-1)" "unprognostic (5.17e-2)" "unprognostic (2.78e-1)" "unprognostic (5.37e-2)" "unprognostic (2.09e-3)" "unprognostic (1.54e-1)" "unprognostic (1.87e-5)" "unprognostic (1.86e-1)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (2.74e-3)" 0.5 0.3 0.3 0.6 0.3 0.4 18.0 0.9 0.5 23.5 0.3 0.3 0.1 0.3 10.5 69.6 1.0 0.3 0.6 0.5 0.5 0.3 0.4 1.9 1.0 0.4 0.6 0.1 0.3 0.0 0.5 10.8 0.7 17.4 0.2 0.0 20.8 18.0 42.4 137.3 0.2 0.3 0.2 0.2 0.4 3.4 0.4 23.1 0.3 12.4 17.7 18.6 54.4 0.4 2.3 4.6 0.0 0.1 0.2 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 16.6 0.6 0.1 0.2 87.1 0.0 167.3 0.0 1.4 0.0 1.9 1.3 0.4 0.0 0.0 0.3 0.2 124.0 0.2 117.3 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.3 0.2 0.0 1.0 0.3 0.0 0.2 185.1 0.2 0.1 0.2 0.0 0.0 2.5 0.9 0.2 0.3 0.2 0.1 0.2 0.0 25.3 0.3 1.1 0.5 0.1 0.8 0.6 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.1 0.0 0.3 0.1 0.1 0.4 0.2 0.0 0.2 0.1 0.0 0.3 0.3 0.9 0.5 0.5 0.5 0.4 0.6 0.7 0.2 0.4 0.4 0.2 0.0 5.3 1.0 0.9 275.4 26.8 61.9 335.2 0.0 0.9 30.1 0.7 0.0 8.5 0.0 0.0 24.9 0.1 0.1 0.0 0.2 1.8 0.0 0.1 1.1 0.0 0.0 1.3 0.2 2.8 1.4 0.0 0.1 0.0 0.0 0.0 0.1 2.4 0.0 4.8 0.0 2.0 0.0 11.9 0.4 0.3 0.7 8.8 14.0 0.6 0.0 0.0 0.5 1.4 1.6 0.0 1.2 1.6 5.6 0.0 0.0 2.8 0.0 0.0 5.3 0.9 0.5 2.4 173.4 283.1 8.9 0.6 0.2 0.0 15.2 TPD52 "D52, hD52, N8L" ENSG00000076554 "Tumor protein D52" P55327 8 80034745-80231232 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 187.6" "Cell type enhanced" "Detected in many" "Ionocytes: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 50.5" "Group enriched" "Detected in many" 5 "B-cells: 50.5;NK-cells: 15.1;T-cells: 22.0" "Cell line enhanced" "Detected in many" "Karpas-707: 252.6;SK-BR-3: 572.5" "HPA028427, HPA062167" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 310000 "Cluster 43: B-cells - Humoral immune response" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "Golgi apparatus" "HPA028427: AB_10610561, HPA062167: AB_2684704" "prognostic unfavorable (1.11e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-2)" "unprognostic (3.77e-3)" "unprognostic (8.24e-2)" "unprognostic (3.75e-1)" "unprognostic (7.99e-3)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.77e-6)" "unprognostic (2.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (1.70e-2)" 5.4 9.2 34.9 28.4 40.2 8.9 75.9 34.2 69.4 19.6 36.6 117.7 98.9 9.9 56.2 34.9 15.3 31.1 11.7 42.9 35.4 46.5 30.7 19.8 44.0 33.2 37.1 2.4 41.8 27.4 34.3 22.9 36.3 104.8 129.7 187.6 80.7 18.3 8.6 46.9 100.3 10.4 32.8 16.0 84.1 5.2 53.3 15.5 64.5 9.8 56.2 20.9 20.2 48.1 131.8 34.9 1.6 23.0 0.0 0.0 51.7 8.6 12.9 34.7 17.1 18.0 37.4 189.9 45.2 0.8 25.5 52.5 52.7 36.3 24.6 23.8 44.2 26.8 46.9 29.4 0.2 8.6 0.7 0.0 25.2 0.1 12.2 21.6 2.0 128.9 0.4 252.6 0.1 43.6 42.6 39.4 11.7 148.8 86.0 0.3 0.7 122.0 60.7 31.6 64.9 44.1 40.1 572.5 110.7 51.0 55.9 34.2 2.1 0.0 35.2 0.6 30.8 94.1 87.1 155.2 22.5 0.2 2.6 0.6 0.1 5.5 12.7 0.1 22.0 50.5 12.4 11.1 2.5 44.7 8.1 9.3 0.5 15.1 0.1 5.2 9.1 8.3 34.9 40.2 34.2 69.4 42.9 35.4 33.2 37.1 36.3 32.8 53.3 48.1 17.3 44.8 67.8 10.4 133.6 80.7 89.6 83.4 51.2 171.1 105.6 54.2 22.2 82.9 78.1 66.2 118.9 98.9 28.6 230.9 170.2 112.8 20.6 25.2 8.4 26.2 169.9 11.6 85.4 79.6 116.9 6.7 97.3 72.8 1.3 15.3 25.7 40.6 13.1 32.0 53.9 331.9 476.0 14.6 24.2 13.0 1.2 10.8 104.9 37.5 91.2 50.3 60.8 69.9 181.0 79.7 317.5 1.5 270.5 214.4 132.3 135.3 21.4 232.2 0.0 49.6 8.3 1.6 18.2 91.4 124.6 231.2 51.3 0.3 247.1 135.4 TPD52L1 "D53, hD53, TPD53" ENSG00000111907 "TPD52 like 1" Q16890 6 125119049-125264407 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.3;salivary gland: 298.3" "Cell type enhanced" "Detected in many" "Astrocytes: 390.1;Squamous epithelial cells: 272.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 269.1;hTCEpi: 234.3;MCF7: 365.5;RPTEC TERT1: 271.4;SK-BR-3: 189.4;T-47d: 162.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027915, HPA027916" Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions, Cytosol" "HPA027915: AB_10602074, HPA027916: AB_10601860" "unprognostic (1.44e-1)" "unprognostic (2.01e-2)" "unprognostic (2.76e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (2.87e-2)" "unprognostic (1.38e-2)" "unprognostic (2.14e-1)" "unprognostic (7.85e-2)" "unprognostic (7.80e-2)" "unprognostic (9.42e-3)" "unprognostic (1.76e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.06e-1)" "unprognostic (6.83e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (5.34e-4)" 44.7 258.3 83.9 10.1 96.2 0.8 67.0 72.6 97.4 35.8 103.4 36.2 9.7 15.2 68.8 152.4 34.6 27.3 71.4 78.4 81.3 40.6 58.4 10.9 6.6 81.4 76.8 20.7 47.1 67.3 24.8 8.9 78.8 41.0 13.0 1.9 298.3 79.1 111.9 47.9 10.6 12.3 68.5 2.0 43.1 5.1 81.5 3.4 60.7 126.2 12.3 59.6 60.8 76.6 37.7 42.0 0.5 269.1 2.4 0.6 63.3 6.2 5.9 0.0 0.7 67.3 46.9 0.1 136.2 31.2 9.1 83.8 8.4 58.2 0.2 0.8 58.0 0.8 58.0 0.5 5.7 0.2 0.1 7.4 234.3 0.1 30.7 82.5 0.0 0.0 30.5 0.6 4.7 365.5 0.0 0.7 4.4 36.8 22.7 0.4 0.1 0.0 271.4 9.8 9.1 0.2 70.5 189.4 4.6 9.6 162.3 0.8 0.2 1.8 5.9 0.5 2.0 0.1 0.1 0.2 1.0 0.3 0.7 1.8 0.5 0.3 0.3 0.2 0.3 0.3 0.6 0.2 0.2 0.4 0.7 0.5 2.7 2.6 0.1 0.4 0.2 0.4 83.9 96.2 72.6 97.4 78.4 81.3 81.4 76.8 78.8 68.5 81.5 76.6 141.6 0.0 28.3 390.1 2.2 19.6 44.6 70.2 128.1 3.8 164.4 154.9 45.8 25.8 51.7 125.0 4.2 32.7 3.2 3.9 176.1 30.7 6.9 71.7 21.1 87.2 16.2 0.0 16.4 110.8 140.2 18.8 13.7 184.5 2.5 29.5 15.4 59.9 10.9 0.0 48.2 11.3 83.4 2.1 5.2 4.9 17.4 3.4 131.6 28.1 0.6 3.9 1.0 11.6 2.9 35.3 2.3 36.5 2.6 37.1 10.9 45.4 15.7 1.3 0.0 177.1 10.1 5.7 9.2 272.2 37.2 14.4 3.5 53.8 17.8 19.2 TPM2 "AMCD1, DA1, NEM4" ENSG00000198467 "Tropomyosin 2" P07951 9 35681992-35690056 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 39012.3;tongue: 16773.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1066.2;Peritubular cells: 2072.1;Sertoli cells: 2222.0;Smooth muscle cells: 2341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 812 "plasmacytoid DC: 398.6" "Lineage enriched" "Detected in single" 920 "dendritic cells: 398.6" "Cell line enhanced" "Detected in many" "BJ: 2309.6;fHDF/TERT166: 1289.0;hTERT-RPE1: 1399.1" "HPA047089, HPA053624" Approved NA NA 140000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (5.56e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (3.34e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-2)" "unprognostic (1.18e-3)" "unprognostic (6.56e-3)" "unprognostic (2.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.51e-10)" "unprognostic (1.43e-2)" "unprognostic (8.33e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-2)" 331.1 285.0 88.0 411.0 89.8 16.7 260.8 92.5 117.3 651.3 127.3 3498.4 217.7 1928.1 201.9 1018.0 849.7 442.4 788.5 84.8 81.1 144.0 41.0 283.1 62.2 86.1 79.2 388.4 73.7 24.1 82.6 142.3 80.5 1219.0 238.0 8.0 393.6 1988.7 39012.3 148.5 636.2 2340.8 78.6 140.1 1252.6 82.9 83.3 26.3 138.9 16773.7 21.2 1630.1 454.9 79.8 375.4 291.2 213.9 33.6 335.4 893.3 129.3 2309.6 934.4 983.0 667.9 12.2 24.2 0.4 213.0 1289.0 144.6 9.2 3.7 291.2 457.0 716.2 10.8 9.1 1054.1 11.8 540.2 2.3 102.7 1067.7 44.9 738.8 0.4 1399.1 235.7 25.3 5.6 0.8 1052.1 15.3 2.7 29.1 269.6 1.5 17.0 18.5 391.5 3.0 31.1 7.2 3.8 13.3 470.0 7.9 18.2 273.8 6.8 27.7 30.0 16.5 585.7 11.6 730.6 0.6 2.7 2.9 34.0 6.5 29.2 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.3 0.4 0.0 0.1 0.0 0.4 0.2 0.0 398.6 0.0 2.1 88.0 89.8 92.5 117.3 84.8 81.1 86.1 79.2 80.5 78.6 83.3 79.8 110.0 3.2 4.1 10.4 5.9 57.1 81.2 274.1 24.5 0.8 29.9 1066.2 619.5 4.3 42.1 7.3 0.0 12.1 116.7 1.4 0.0 21.4 4.3 20.3 488.3 80.3 2.4 4.0 2.5 5.7 104.8 332.6 99.4 18.7 2.5 142.0 181.3 1.4 32.4 1.7 4.6 1.9 48.8 3.1 77.9 32.4 283.0 24.2 67.6 9.4 6.5 11.7 1.0 3.0 0.4 8.4 0.1 2072.1 2.9 169.8 0.4 1.3 23.5 0.9 2222.0 594.8 2341.4 2.5 27.3 6.7 42.8 14.6 16.0 106.7 2.8 28.7 TPPP "p25, p25alpha, TPPP/p25, TPPP1" ENSG00000171368 "Tubulin polymerization promoting protein" O94811 5 659862-693352 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 185.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Excitatory neurons: 45.2;Horizontal cells: 42.1;Inhibitory neurons: 32.6;Oligodendrocytes: 104.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.4;AN3-CA: 5.4;SCLC-21H: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036575, HPA036576" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Mitochondria, Cytosol" "HPA036575: AB_10673501, HPA036576: AB_2675200" "unprognostic (3.66e-2)" "unprognostic (3.70e-3)" "unprognostic (9.98e-3)" "unprognostic (7.82e-2)" "unprognostic (2.05e-2)" "unprognostic (3.20e-2)" "unprognostic (2.12e-1)" "unprognostic (3.80e-3)" "unprognostic (3.85e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-3)" "unprognostic (5.48e-2)" "prognostic favorable (5.40e-6)" "unprognostic (4.03e-2)" "unprognostic (2.30e-1)" "unprognostic (2.03e-2)" "unprognostic (3.31e-2)" 3.8 6.6 100.8 0.7 136.7 0.2 2.5 55.3 120.4 1.8 0.0 12.8 5.2 3.3 0.5 11.0 10.4 1.7 9.8 112.3 69.9 4.4 2.7 10.2 0.3 110.3 102.3 1.8 6.0 2.1 19.5 2.2 107.7 2.3 1.8 6.3 5.7 3.6 10.5 8.2 9.5 3.6 47.5 2.6 4.9 2.2 124.6 0.4 6.9 5.3 1.4 6.8 2.7 185.2 0.2 7.4 0.3 5.4 0.8 0.0 1.0 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.5 0.0 1.9 2.9 2.9 0.0 0.0 1.5 2.5 0.2 3.6 0.2 0.8 0.2 0.3 0.0 0.7 0.0 0.1 0.2 0.0 0.1 0.1 2.7 0.0 0.2 0.2 0.5 0.2 0.8 0.7 0.3 0.1 1.0 0.2 1.0 13.2 1.6 0.8 0.3 3.6 0.3 0.7 0.2 0.1 0.2 2.7 0.0 0.2 1.0 0.2 0.0 0.5 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 100.8 136.7 55.3 120.4 112.3 69.9 110.3 102.3 107.7 47.5 124.6 185.2 1.6 38.5 10.0 6.8 0.7 4.1 1.4 0.6 9.6 21.3 3.1 2.4 18.4 2.8 5.3 1.8 0.0 0.0 1.1 5.7 1.9 2.4 9.1 26.6 0.9 2.0 10.2 0.0 45.2 0.7 0.3 3.3 3.1 5.8 4.5 0.1 2.2 4.3 3.3 42.1 32.6 6.5 0.0 0.0 2.2 7.2 0.3 1.2 1.8 4.7 0.1 0.9 0.0 6.6 104.7 0.7 5.2 0.4 3.3 0.8 10.3 1.1 13.5 2.4 0.0 1.5 4.2 2.2 0.8 6.7 3.1 0.0 4.8 0.1 4.8 4.1 TPRN "C9orf75, DFNB79, FLJ90254" ENSG00000176058 Taperin Q4KMQ1 9 137191617-137204193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.4;pancreas: 91.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 177.7;Proximal enterocytes: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 61.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 23.6" "HPA020899, HPA076667" Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA020899: AB_1845835, HPA076667: " "unprognostic (5.41e-2)" "prognostic favorable (2.13e-4)" "unprognostic (2.94e-1)" "unprognostic (9.28e-2)" "unprognostic (1.68e-1)" "unprognostic (2.61e-2)" "unprognostic (3.59e-3)" "unprognostic (8.20e-2)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.89e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.16e-9)" "unprognostic (1.96e-3)" "unprognostic (6.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.44e-2)" 3.7 5.1 24.3 4.4 37.8 2.7 4.8 29.9 33.1 5.2 15.1 25.4 22.0 4.7 0.9 20.5 5.1 3.2 10.7 23.5 23.7 19.1 24.3 8.1 2.4 33.1 32.4 6.4 91.4 2.5 6.0 3.3 28.2 8.0 6.9 1.7 11.8 3.4 6.2 15.6 26.0 1.5 20.8 5.0 29.3 9.3 31.9 2.0 5.5 3.1 1.5 7.8 6.9 56.4 10.2 11.4 3.8 17.0 5.2 5.5 30.1 7.0 4.3 7.0 3.9 38.5 12.1 18.6 10.1 3.6 9.2 30.4 7.9 3.9 0.9 11.9 11.1 8.7 17.5 25.5 7.9 13.5 10.8 4.7 7.5 6.2 4.3 4.6 4.5 8.2 16.1 6.4 2.1 61.9 8.9 29.0 13.5 55.5 14.8 26.3 9.1 28.4 15.9 21.0 24.4 8.9 10.8 49.6 13.0 2.9 57.8 21.0 5.0 12.7 6.0 20.1 15.1 5.3 11.0 9.7 9.1 12.1 7.2 0.0 0.8 0.0 0.3 0.8 0.1 0.3 0.3 0.5 0.6 0.3 0.1 0.3 0.0 0.8 0.4 0.6 0.6 0.2 24.3 37.8 29.9 33.1 23.5 23.7 33.1 32.4 28.2 20.8 31.9 56.4 4.6 19.2 5.5 6.2 3.5 1.8 1.3 2.6 2.2 19.3 13.2 9.5 7.6 15.7 2.6 16.5 6.2 5.4 8.4 177.7 7.9 8.0 3.1 7.6 4.1 2.9 9.0 7.4 3.3 45.4 1.3 3.0 15.3 9.6 1.3 8.7 3.9 19.5 3.6 11.8 3.8 46.0 6.1 2.8 1.6 5.3 3.4 5.2 5.4 1.0 2.8 12.4 1.0 2.5 30.4 15.3 39.7 4.5 1.9 3.3 95.9 20.0 2.3 7.3 6.6 3.2 4.5 2.7 4.4 5.8 2.8 1.9 4.5 10.3 36.7 1.7 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.0;lymphoid tissue: 70.3;testis: 30.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 90.7;Extravillous trophoblasts: 68.5;Granulosa cells: 46.6;Spermatocytes: 114.5;Spermatogonia: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.1;NK-cells: 3.6;T-cells: 8.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.9 1.4 0.9 13.0 0.9 48.0 2.7 0.8 1.0 2.3 0.5 11.6 9.4 2.4 0.2 13.2 0.9 1.8 0.8 1.1 0.6 0.7 4.2 1.9 26.6 0.6 1.0 0.5 0.4 0.4 0.2 8.3 0.7 0.7 14.2 0.5 2.0 0.5 1.4 9.8 9.4 6.8 0.6 5.2 6.2 30.7 1.3 70.3 1.0 0.8 32.3 3.4 4.1 0.9 455.1 149.1 176.4 139.1 13.8 25.2 169.8 186.1 104.5 264.0 197.7 319.1 190.4 212.4 106.7 104.5 196.8 232.7 203.7 169.0 298.8 92.3 78.8 416.3 139.7 219.6 4.2 161.9 102.8 8.7 9.1 166.0 120.0 37.9 144.6 157.1 313.8 187.8 209.7 186.2 272.2 125.3 197.1 174.0 159.3 152.5 475.5 128.2 71.2 72.8 127.5 85.7 284.6 106.3 82.0 120.9 185.1 97.3 98.3 294.1 179.7 136.5 290.0 74.4 138.6 187.3 92.2 565.1 195.8 5.1 0.0 0.4 0.4 0.0 0.2 0.6 1.4 1.7 0.5 0.2 0.3 0.5 0.2 3.6 0.1 1.0 8.1 1.0 0.9 0.9 0.8 1.0 1.1 0.6 0.6 1.0 0.7 0.6 1.3 0.9 1.0 0.0 4.2 0.0 5.9 6.9 1.5 4.3 1.2 0.9 3.0 3.4 0.9 4.3 3.8 0.0 0.0 23.3 3.8 6.4 0.0 1.2 9.3 7.3 6.6 3.9 1.2 90.7 2.9 0.4 68.5 9.2 16.3 8.4 0.0 46.6 8.9 3.0 19.5 1.7 0.9 9.8 10.2 8.0 5.5 13.1 0.9 7.6 0.0 1.0 2.1 0.4 3.1 0.5 0.5 1.8 1.4 0.0 30.8 2.5 0.9 0.0 0.7 0.4 0.0 1.1 15.4 114.5 63.1 31.2 6.1 4.7 8.2 4.2 18.4 2.9 TRAFD1 FLN29 ENSG00000135148 "TRAF-type zinc finger domain containing 1" O14545 12 112125538-112153604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 117.6;Spermatocytes: 75.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039254, HPA039266" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm Cytosol "HPA039254: AB_10805358, HPA039266: AB_10795142" "unprognostic (7.80e-2)" "prognostic favorable (5.73e-4)" "unprognostic (6.12e-2)" "unprognostic (1.44e-1)" "unprognostic (9.46e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.21e-3)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (9.26e-6)" "unprognostic (1.07e-1)" "unprognostic (6.15e-2)" "unprognostic (3.33e-3)" "prognostic favorable (3.92e-5)" 17.1 14.6 15.9 30.4 21.5 30.1 20.3 21.2 18.9 21.2 24.7 40.6 16.7 16.8 15.6 32.0 15.4 17.7 22.3 15.1 17.3 15.7 13.5 26.3 37.1 22.4 20.0 18.7 11.8 15.7 11.7 19.0 23.0 22.0 20.6 18.7 19.0 19.8 12.9 35.9 20.3 25.9 20.5 31.3 17.2 29.1 20.1 32.6 13.8 11.4 40.4 29.9 21.7 30.2 23.8 26.2 41.8 40.8 28.8 27.3 22.1 27.2 38.8 36.5 29.4 29.5 21.9 27.4 22.6 28.9 15.7 49.0 42.0 26.3 24.2 47.3 40.1 44.4 37.7 16.3 50.0 27.1 67.7 34.4 43.5 27.1 35.7 37.2 32.6 16.6 50.1 16.9 23.6 41.2 31.5 39.0 35.4 27.8 31.8 43.8 25.6 46.8 24.3 89.5 36.4 27.3 57.4 55.7 15.1 30.8 35.8 38.7 22.1 17.2 12.2 17.1 14.3 40.3 36.2 29.3 18.5 21.6 19.1 323.7 96.1 226.1 45.1 86.8 30.1 56.7 43.1 40.3 50.1 60.2 39.4 36.6 188.2 70.8 93.1 33.5 63.7 101.2 15.9 21.5 21.2 18.9 15.1 17.3 22.4 20.0 23.0 20.5 20.1 30.2 10.7 19.2 13.1 6.8 12.4 12.2 7.4 18.5 30.7 7.0 14.7 11.8 10.9 5.7 18.9 12.9 25.0 20.1 8.5 15.4 5.9 21.3 1.7 9.0 14.3 11.3 15.6 9.0 8.4 20.8 15.6 15.1 15.3 7.5 12.0 10.0 7.9 5.7 14.8 15.2 12.2 10.3 30.5 11.9 9.9 3.7 11.8 14.0 7.2 7.5 117.6 9.9 19.6 10.6 28.6 25.8 15.5 12.8 8.7 22.7 13.0 6.3 10.2 10.9 0.0 5.6 8.8 75.6 36.0 22.0 15.2 26.4 14.0 10.0 9.4 14.4 TRAK1 "KIAA1042, MILT1, OIP106" ENSG00000182606 "Trafficking kinesin protein 1" Q9UPV9 3 42013802-42225890 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 168.9;skeletal muscle: 262.4;tongue: 202.6" "Cell type enhanced" "Detected in all" "Astrocytes: 173.0;Cardiomyocytes: 262.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RT4: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005853, HPA011367" Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" Nucleoplasm "HPA005853: AB_1854778, HPA011367: AB_2668495" "unprognostic (5.55e-2)" "unprognostic (1.38e-2)" "unprognostic (5.49e-2)" "unprognostic (2.52e-2)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (1.95e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" "unprognostic (3.01e-2)" "unprognostic (3.56e-3)" "prognostic favorable (4.84e-8)" "unprognostic (3.65e-2)" "unprognostic (1.70e-1)" "unprognostic (1.00e-2)" "unprognostic (4.61e-3)" 26.0 13.1 23.0 17.1 26.2 18.2 18.0 28.5 27.7 13.7 27.8 27.1 34.5 12.2 10.4 29.3 19.8 26.9 168.9 24.2 19.5 20.1 15.3 24.1 22.8 24.4 30.3 8.5 13.1 32.2 17.7 15.3 21.6 15.4 25.4 96.7 44.1 13.1 262.4 45.1 42.0 16.8 19.1 22.2 61.0 12.1 26.0 17.9 31.4 202.6 22.6 33.8 18.4 21.4 22.2 19.2 37.9 16.4 25.6 24.9 48.9 29.5 33.5 19.0 20.6 12.8 30.7 43.9 15.1 75.2 20.4 10.7 26.5 68.8 20.6 39.6 18.8 30.4 19.9 35.6 12.8 34.6 22.9 21.4 28.9 41.9 38.0 28.1 38.6 11.6 15.7 34.4 24.4 9.2 3.7 18.1 16.4 60.4 14.8 16.1 14.1 36.8 26.3 165.3 23.8 27.9 11.3 16.3 16.2 31.4 14.6 29.3 39.6 16.6 19.2 99.0 17.4 25.7 23.0 38.9 18.2 30.2 16.4 0.9 1.3 0.5 0.6 2.4 0.5 2.4 0.9 0.7 1.5 3.6 0.3 0.9 0.6 1.0 1.4 2.5 0.4 0.7 23.0 26.2 28.5 27.7 24.2 19.5 24.4 30.3 21.6 19.1 26.0 21.4 27.4 32.1 32.4 173.0 23.9 38.0 16.3 32.1 30.1 22.7 18.5 17.7 262.0 24.3 38.1 14.7 100.1 23.0 13.9 61.4 1.9 10.8 1.1 53.3 21.8 23.9 22.8 6.5 62.0 12.3 18.3 14.0 81.1 70.0 10.8 11.5 6.8 10.3 15.7 33.7 81.3 39.5 26.4 15.7 33.4 3.0 1.8 23.3 24.9 97.4 17.9 27.8 4.1 105.1 64.8 24.2 37.1 2.6 5.4 18.5 97.9 10.2 80.6 139.9 32.9 15.9 29.9 1.0 3.9 27.5 43.2 15.7 7.5 4.6 35.6 27.0 TRAK2 "ALS2CR3, CALS-C, GRIF-1, KIAA0549, MILT2, OIP98" ENSG00000115993 "Trafficking kinesin protein 2" O60296 2 201377207-201451500 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 157.8;Erythroid cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015827, HPA062163" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Nuclear bodies" Vesicles "HPA015827: AB_1858238, HPA062163: AB_2684702" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" "unprognostic (2.56e-2)" "unprognostic (4.31e-2)" "unprognostic (2.78e-1)" "unprognostic (1.76e-1)" "unprognostic (2.38e-2)" "unprognostic (3.08e-2)" "unprognostic (2.24e-1)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "prognostic favorable (7.42e-5)" "unprognostic (1.48e-1)" "unprognostic (3.24e-1)" "unprognostic (1.40e-2)" "unprognostic (9.82e-3)" 24.1 20.3 53.2 16.4 63.7 52.2 14.8 61.2 60.9 16.1 55.6 22.4 13.4 14.3 13.0 16.7 13.9 18.7 70.9 47.3 54.0 23.7 14.1 20.7 17.3 92.9 67.6 9.7 15.4 26.6 12.4 23.7 86.8 12.8 22.8 20.1 26.4 15.2 14.8 8.1 16.1 20.4 99.9 18.1 12.2 7.8 69.7 12.4 34.9 26.8 13.6 15.7 9.0 102.2 11.6 15.5 9.4 34.3 61.6 87.4 10.6 39.2 32.8 27.4 31.9 24.4 9.8 7.1 16.3 50.6 26.4 11.2 20.0 12.9 43.5 21.4 13.0 15.5 25.6 15.9 33.8 12.3 18.4 48.4 10.8 28.8 22.2 27.5 40.4 11.0 12.4 26.9 55.8 16.6 9.6 6.9 10.6 11.3 32.7 12.1 24.9 10.6 21.9 15.6 18.6 24.0 21.0 15.5 63.6 13.6 12.4 12.4 50.2 44.2 16.6 31.0 25.7 16.2 30.2 8.3 37.2 18.2 24.4 2.6 5.5 6.2 7.8 7.0 7.3 9.3 10.1 6.7 4.3 14.2 6.9 7.3 3.4 11.1 6.5 2.3 12.6 6.0 53.2 63.7 61.2 60.9 47.3 54.0 92.9 67.6 86.8 99.9 69.7 102.2 34.0 16.0 29.8 37.5 17.8 8.3 3.4 6.3 11.4 45.4 14.4 8.8 157.8 22.8 13.4 9.2 73.0 10.3 9.3 27.9 7.9 13.9 1.9 12.7 20.9 21.0 29.5 181.0 92.3 14.7 4.8 16.9 10.7 25.7 19.6 10.3 15.0 14.3 10.6 77.4 75.6 20.6 10.2 12.9 7.7 3.8 8.1 13.2 26.6 22.5 14.2 5.1 12.3 47.7 57.0 10.7 14.5 12.8 16.8 5.7 21.7 8.9 14.9 22.1 13.1 23.2 23.3 9.4 12.8 16.2 4.1 5.6 16.6 18.7 24.5 7.2 TRANK1 "KIAA0342, LBA1" ENSG00000168016 "Tetratricopeptide repeat and ankyrin repeat containing 1" O15050 3 36826819-36945057 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 45.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.5;Granulosa cells: 73.0;Inhibitory neurons: 91.8;Microglial cells: 52.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 115.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 115.1" "Cell line enhanced" "Detected in many" "Daudi: 67.9;HMC-1: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035508 Approved Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA035508: AB_10671105" "unprognostic (7.11e-3)" "unprognostic (1.55e-2)" "unprognostic (3.05e-2)" "unprognostic (2.34e-1)" "unprognostic (4.84e-2)" "unprognostic (2.04e-3)" "unprognostic (9.13e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-1)" "unprognostic (8.59e-2)" "unprognostic (3.83e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (1.82e-3)" "unprognostic (1.07e-3)" 7.4 4.6 1.7 14.0 2.5 10.0 6.4 5.2 7.5 24.6 0.0 14.8 11.1 18.0 5.2 3.2 45.0 9.6 6.2 1.8 2.3 3.4 9.9 8.8 18.7 1.9 0.5 15.6 2.4 3.2 6.7 5.2 1.8 16.5 13.4 1.4 6.8 6.3 1.1 2.3 16.7 8.8 3.4 13.1 8.2 2.4 3.3 17.5 6.2 2.5 20.8 16.6 10.0 0.7 1.4 1.7 0.4 0.0 4.5 17.9 0.0 1.4 9.1 3.9 8.0 0.0 7.2 67.9 2.8 5.3 13.5 0.5 0.2 1.0 0.7 3.7 0.1 11.6 4.8 0.0 5.5 3.1 26.1 5.7 3.5 3.1 0.2 1.1 5.4 7.6 9.5 9.9 2.4 0.1 8.9 1.3 0.5 0.0 1.9 2.5 0.3 1.4 1.5 3.3 0.6 0.0 7.2 1.9 0.7 0.8 1.2 3.8 3.7 3.4 1.3 0.2 1.2 9.3 2.2 15.8 0.6 2.6 0.4 7.3 2.0 11.5 14.9 2.9 10.7 10.9 12.3 15.3 1.4 17.5 11.0 10.6 115.1 8.5 3.9 0.2 11.6 3.0 1.7 2.5 5.2 7.5 1.8 2.3 1.9 0.5 1.8 3.4 3.3 0.7 5.4 16.0 7.8 18.3 18.8 0.8 1.3 1.7 6.8 4.4 1.6 2.3 3.6 1.5 4.0 3.7 2.1 1.3 16.5 40.9 0.0 3.1 0.4 6.1 15.1 5.5 5.4 12.6 56.5 1.8 1.6 7.1 18.8 8.8 6.3 73.0 5.7 17.7 5.0 0.0 91.8 16.7 0.0 6.6 0.8 0.0 4.4 7.4 5.4 52.5 8.7 1.6 26.8 23.6 13.2 3.2 16.9 6.0 21.9 1.6 16.7 0.9 5.2 0.7 0.0 2.6 5.2 0.3 0.3 2.6 0.9 0.7 21.8 3.7 4.0 1.5 TRAPPC9 "IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120" ENSG00000167632 "Trafficking protein particle complex 9" Q96Q05 8 139727725-140458579 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 89.5;Excitatory neurons: 121.8;Inhibitory neurons: 136.3;Late spermatids: 119.0;Microglial cells: 105.9;Oligodendrocyte precursor cells: 93.5;Oligodendrocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026579 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA026579: AB_1854459" "unprognostic (1.82e-2)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-2)" "unprognostic (2.30e-1)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (8.14e-2)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.76e-2)" "unprognostic (2.31e-1)" "prognostic favorable (5.11e-6)" "unprognostic (2.09e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.62e-1)" 8.6 13.4 10.3 6.9 11.0 11.1 8.9 10.7 12.7 10.3 12.5 11.1 8.0 11.3 5.1 12.3 12.2 5.8 15.0 10.8 10.3 13.8 11.6 9.5 8.0 13.1 14.1 10.5 11.9 27.4 20.7 7.2 13.9 11.7 6.0 14.2 11.6 8.3 33.5 11.4 10.9 7.2 10.2 11.3 12.5 9.0 11.9 11.3 12.9 17.6 6.8 11.1 10.8 13.0 9.6 16.6 7.4 20.8 15.5 9.0 4.9 6.0 9.9 3.1 5.0 6.2 11.2 11.6 14.0 11.9 4.7 12.2 10.0 9.4 3.4 16.8 6.1 18.6 9.8 6.2 11.2 4.7 14.5 8.9 9.3 2.5 7.9 11.1 12.9 13.1 6.7 10.1 5.1 27.0 29.2 6.2 2.3 31.3 14.0 12.2 2.7 19.4 11.6 11.6 19.1 10.6 9.8 4.7 10.6 7.6 15.3 6.8 7.7 4.6 7.9 10.8 4.9 14.1 10.9 7.8 9.6 10.1 7.4 15.4 3.5 2.9 4.2 3.3 4.6 2.7 2.9 3.3 3.5 4.4 2.8 3.6 5.0 4.9 3.4 4.2 2.1 3.5 10.3 11.0 10.7 12.7 10.8 10.3 13.1 14.1 13.9 10.2 11.9 13.0 5.1 3.2 8.3 89.5 9.6 2.3 4.7 3.1 5.7 14.2 5.5 4.1 13.9 5.7 5.3 11.0 20.9 10.9 5.4 15.2 9.8 6.5 47.9 8.4 3.7 6.5 30.5 3.4 121.8 6.2 4.4 5.3 29.6 10.2 8.8 7.9 4.6 9.2 7.5 28.6 136.3 14.4 10.2 10.5 3.7 119.0 5.9 10.3 10.6 105.9 5.3 13.6 11.3 93.5 170.6 5.1 6.6 7.9 11.0 3.7 13.4 19.9 15.7 13.7 6.6 9.0 5.3 3.6 6.6 8.7 3.0 14.6 10.5 8.6 12.0 5.4 TRARG1 "BEC-1, DSPB1, IFITMD3, LOST1, TUSC5" ENSG00000184811 "Trafficking regulator of GLUT4 (SLC2A4) 1" Q8IXB3 17 1279662-1300978 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 34 "adipose tissue: 101.4;breast: 68.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 294 "ASC diff: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050825 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050825: AB_2681252" "unprognostic (5.84e-2)" "unprognostic (7.21e-2)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (2.01e-1)" "unprognostic (2.91e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.83e-2)" "unprognostic (2.66e-1)" "unprognostic (5.79e-2)" "unprognostic (1.90e-3)" "unprognostic (6.26e-2)" "unprognostic (3.12e-1)" "unprognostic (5.10e-1)" 101.4 1.1 0.0 1.2 0.0 0.0 68.7 0.0 0.4 0.4 0.0 1.2 0.0 0.2 0.0 0.1 0.1 0.6 1.7 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 1.2 2.1 2.3 0.0 0.0 0.0 0.6 0.6 0.0 0.1 1.0 0.6 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 79.8" "Cell type enriched" "Detected in some" 10 "T-cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 395.1" "Group enriched" "Detected in many" 155 "granulocytes: 395.1;T-cells: 313.1" "Group enriched" "Detected in some" 25 "JURKAT: 29.9;MOLT-4: 76.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: AB_1080375, HPA072760: " "unprognostic (1.54e-4)" "unprognostic (1.41e-3)" "unprognostic (6.82e-2)" "unprognostic (4.95e-3)" "unprognostic (2.84e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (2.02e-2)" "unprognostic (7.21e-3)" "unprognostic (8.96e-3)" "unprognostic (8.03e-2)" "unprognostic (4.32e-1)" "unprognostic (2.86e-5)" "unprognostic (3.12e-1)" "unprognostic (3.01e-2)" "unprognostic (2.90e-4)" "unprognostic (4.36e-2)" 1.1 0.6 0.0 11.0 0.0 2.7 0.8 0.0 0.0 0.4 0.0 1.3 1.4 0.4 0.4 1.0 0.3 2.5 0.4 0.1 0.0 0.3 1.3 2.1 23.9 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.8 1.5 0.0 0.6 0.1 0.1 0.6 3.0 0.5 0.0 8.5 2.4 0.4 0.0 79.8 0.4 0.4 12.4 2.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 2.1 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 395.1 0.6 0.2 57.0 0.2 116.4 1.0 229.5 119.6 0.3 0.4 313.1 77.7 3.5 2.2 0.7 0.8 111.1 139.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.0 3.3 8.4 0.1 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 1.8 0.0 0.0 8.9 0.1 0.0 0.0 2.3 0.1 0.1 1.1 0.0 2.7 0.1 0.0 0.0 1.7 7.7 0.1 2.5 0.0 1.8 0.6 0.2 0.0 0.2 0.0 0.0 1.0 12.2 2.2 0.0 1.8 3.6 0.0 3.2 0.0 3.1 0.0 0.2 0.0 0.0 0.0 5.1 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.8 0.0 0.1 0.0 8.0 0.1 129.3 0.6 0.0 0.2 TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1520.1" "Group enriched" "Detected in many" 10 "dendritic cells: 338.0;NK-cells: 580.9;T-cells: 399.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 3232.4" "Lineage enriched" "Detected in all" 9 "T-cells: 3232.4" "Cell line enriched" "Detected in some" 5 "JURKAT: 1467.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.08e-4)" "unprognostic (7.96e-4)" "unprognostic (6.02e-2)" "unprognostic (1.26e-4)" "unprognostic (1.81e-2)" "unprognostic (5.42e-5)" "unprognostic (1.76e-2)" "unprognostic (6.94e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.56e-1)" "unprognostic (3.18e-6)" "unprognostic (3.98e-1)" "unprognostic (8.83e-3)" "unprognostic (1.02e-1)" "unprognostic (4.19e-3)" 9.2 5.1 1.3 140.0 1.5 53.5 9.5 1.1 2.1 7.7 1.5 18.5 26.8 6.4 5.7 12.0 7.0 26.7 5.0 1.0 1.1 5.4 11.4 31.5 322.2 2.0 1.2 6.4 2.7 0.9 2.0 2.3 1.7 9.0 19.4 0.0 19.0 4.6 1.0 9.9 49.7 4.2 1.7 92.5 27.1 2.7 1.6 1520.1 8.4 2.1 227.0 33.2 6.2 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 1467.5 2.0 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 296.5 2.0 0.0 1.9 0.0 45.6 7.2 4.7 869.6 3.5 693.8 17.1 1893.1 1259.3 5.8 15.7 1989.8 1450.7 37.3 359.8 8.3 9.7 3232.4 1917.5 1.3 1.5 1.1 2.1 1.0 1.1 2.0 1.2 1.7 1.7 1.6 1.9 7.3 19.2 40.8 0.0 11.7 0.0 0.3 0.0 0.0 0.0 5.9 5.5 0.0 0.0 3.1 1.8 0.0 0.2 338.0 0.0 0.0 0.5 0.6 1.1 0.7 1.5 0.0 10.7 0.0 0.0 0.1 3.2 4.6 0.8 20.2 0.0 5.3 1.5 0.3 0.0 0.0 0.1 0.0 8.4 0.0 1.9 17.4 13.9 0.0 0.0 17.3 0.0 580.9 0.0 0.0 0.0 0.1 8.2 23.6 0.3 0.0 2.4 0.7 0.0 0.0 1.1 3.5 0.0 0.1 0.5 0.0 0.1 399.0 0.1 0.1 0.4 TRBC2 TCRBC2 ENSG00000211772 "T cell receptor beta constant 2" 7 142801041-142802748 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 115.8;lymphoid tissue: 190.2" "Group enriched" "Detected in many" 4 "B-cells: 164.7;dendritic cells: 358.8;NK-cells: 264.7;T-cells: 498.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 76.0" "Lineage enriched" "Detected in many" 7 "T-cells: 76.0" "Cell line enriched" "Detected in some" 45 "MOLT-4: 277.9" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "prognostic favorable (8.04e-5)" "prognostic favorable (1.80e-4)" "unprognostic (4.19e-3)" "prognostic favorable (3.42e-8)" "unprognostic (5.53e-2)" "prognostic favorable (6.58e-5)" "unprognostic (3.21e-2)" "unprognostic (1.30e-2)" "prognostic favorable (2.81e-4)" "unprognostic (7.53e-3)" "unprognostic (5.96e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (4.09e-3)" 18.9 3.1 0.4 3.9 0.3 1.5 8.6 0.1 1.2 11.9 0.1 21.2 1.7 8.7 0.0 14.6 15.7 2.2 4.9 0.3 0.0 9.6 12.7 32.3 8.6 0.2 0.3 18.3 3.5 0.1 4.0 0.0 0.2 14.2 2.7 0.0 7.9 0.1 3.3 6.5 115.8 0.5 0.1 190.2 16.9 8.7 0.3 109.2 16.4 1.2 10.9 14.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 3.5 0.0 0.0 0.0 0.0 277.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 35.0 8.1 47.6 47.3 0.3 7.7 46.6 40.3 2.0 10.5 0.1 0.0 76.0 42.4 0.4 0.3 0.1 1.2 0.3 0.0 0.2 0.3 0.2 0.1 0.3 0.1 8.3 9.6 52.4 0.0 164.7 0.0 0.3 0.0 1.8 0.1 6.2 9.7 4.8 5.7 3.7 1.8 0.0 0.4 358.8 1.4 0.0 2.9 1.0 1.1 0.8 4.0 0.0 16.6 0.0 1.3 0.1 10.8 8.6 0.9 20.2 0.0 15.0 1.6 0.4 0.0 0.0 0.8 0.0 9.0 0.0 4.2 63.6 18.9 0.0 0.0 19.0 15.6 264.7 0.0 0.0 20.1 0.1 70.3 30.6 0.4 0.1 2.2 2.9 0.4 65.7 4.2 12.4 0.1 0.8 1.3 0.0 0.3 498.0 1.4 0.9 0.2 TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 1014.1" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Group enriched" "Detected in some" 4 "hTCEpi: 74.6;THP-1: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" 10.7 13.2 28.1 3.5 31.1 0.2 9.8 33.7 61.5 6.5 29.1 3.5 0.9 1.6 2.3 0.6 7.4 9.7 2.1 27.5 32.3 1.3 2.3 30.1 2.6 44.5 34.4 2.4 3.9 7.4 3.9 10.7 42.7 2.0 4.3 1.9 6.0 3.1 0.4 0.5 1.4 4.5 46.7 0.5 2.5 0.7 43.5 1.8 1.7 0.0 0.4 4.5 0.6 69.8 0.0 0.3 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 1.2 74.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 42.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 28.1 31.1 33.7 61.5 27.5 32.3 44.5 34.4 42.7 46.7 43.5 69.8 1.8 6.4 7.5 0.0 0.7 0.8 0.2 79.8 0.0 0.3 1.8 58.8 0.1 1.5 9.6 0.0 0.0 5.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 0.0 0.0 0.0 4.9 1.2 0.0 0.0 2.5 0.0 2.2 0.2 1014.1 0.0 0.0 0.0 2.0 34.7 5.2 1.0 0.6 120.5 0.0 12.2 8.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.3 1.0 6.6 0.1 1.0 0.0 0.0 0.0 0.1 7.3 0.8 0.0 0.0 0.1 TREX2 ENSG00000183479 "Three prime repair exonuclease 2" Q9BQ50 X 153444720-153470587 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 24.5" "Cell type enhanced" "Detected in single" "Suprabasal keratinocytes: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 11 "basophil: 1.7;eosinophil: 2.7" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "HEK 293: 5.4;U-698: 7.3;U-937: 7.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA054060 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA054060: AB_2682362" "unprognostic (2.32e-2)" "unprognostic (2.05e-3)" "unprognostic (1.13e-3)" "unprognostic (7.18e-4)" "unprognostic (6.05e-2)" "unprognostic (1.81e-2)" "unprognostic (8.40e-2)" "unprognostic (2.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (1.52e-1)" "unprognostic (9.34e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-2)" 0.9 0.5 0.4 0.6 0.4 0.7 0.8 0.5 1.1 3.2 5.0 0.6 0.2 1.2 0.6 2.9 1.2 0.7 1.0 0.7 0.2 1.4 0.6 1.1 1.4 0.5 0.3 0.9 0.8 0.2 0.7 0.9 0.5 1.3 0.2 0.0 1.9 2.4 0.3 24.5 1.1 0.5 0.3 2.4 0.7 1.0 0.4 0.5 1.3 0.1 1.1 0.6 3.2 0.4 2.1 2.6 0.2 0.9 0.3 0.5 0.2 0.6 0.5 0.5 1.4 0.7 0.5 0.2 1.3 0.5 0.1 2.2 0.9 1.4 0.0 2.3 5.4 0.2 0.5 0.3 0.2 0.6 1.4 0.6 1.3 0.6 0.5 0.3 0.2 0.4 0.3 2.5 0.1 2.5 1.5 1.6 0.8 0.4 1.7 3.5 0.7 1.7 0.2 0.7 0.6 0.3 0.2 0.2 0.8 0.0 0.4 0.7 0.0 0.9 1.6 2.0 0.8 2.8 2.1 7.3 0.2 7.0 1.1 1.7 0.0 2.7 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.5 1.1 0.7 0.2 0.5 0.3 0.5 0.3 0.4 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.7 0.1 0.1 0.0 0.1 TRGC2 "TCRGC2, TRGC2(2X), TRGC2(3X)" ENSG00000227191 "T cell receptor gamma constant 2" 7 38239580-38249572 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 30.5;lymphoid tissue: 34.6;prostate: 23.7" "Group enriched" "Detected in some" 7 "dendritic cells: 149.1;NK-cells: 90.6;T-cells: 122.0" "Cancer enriched" "Detected in many" 18 "prostate cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 720.5" "Lineage enriched" "Detected in many" 5 "T-cells: 720.5" "Cell line enhanced" "Detected in some" "HL-60: 11.4;JURKAT: 36.6;NB-4: 29.9;SK-BR-3: 9.8;U-937: 53.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.79e-3)" "prognostic favorable (1.06e-5)" "unprognostic (1.62e-4)" "unprognostic (3.52e-5)" "unprognostic (3.34e-1)" "unprognostic (1.46e-3)" "unprognostic (8.79e-4)" "unprognostic (4.60e-2)" "unprognostic (1.10e-2)" "unprognostic (1.91e-3)" "unprognostic (1.12e-1)" "unprognostic (3.90e-1)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-3)" 3.6 1.1 8.8 5.1 9.0 30.5 1.8 8.6 19.6 1.5 7.1 3.5 4.5 1.3 3.2 1.1 2.2 3.9 0.9 8.4 8.5 1.6 3.6 9.7 17.5 9.6 8.9 0.5 0.8 0.2 1.0 0.5 9.2 23.7 4.0 0.1 1.8 0.8 0.4 0.6 8.0 1.0 9.3 29.7 3.8 2.2 10.2 34.6 2.1 0.1 7.0 3.4 2.3 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 3.7 1.2 29.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.9 0.0 1.1 1.3 1.4 720.5 1.2 287.4 0.6 64.8 341.6 1.0 0.3 13.5 212.9 4.9 149.7 1.0 1.2 1.3 167.5 8.8 9.0 8.6 19.6 8.4 8.5 9.6 8.9 9.2 9.3 10.2 9.5 1.2 0.0 2.4 0.0 2.4 0.0 0.2 0.0 0.0 0.0 1.0 1.3 0.7 1.5 0.6 0.0 0.0 0.0 149.1 0.3 0.0 0.2 15.5 0.2 0.1 0.8 0.0 6.6 0.0 0.0 0.0 0.4 2.6 0.2 0.0 0.2 3.9 1.0 0.0 0.0 0.0 0.5 0.0 3.5 0.0 6.7 0.0 2.8 0.0 0.0 10.6 0.0 90.6 0.0 0.0 0.0 0.0 0.4 14.2 2.8 0.0 0.5 0.0 0.0 0.0 0.2 1.3 0.8 0.2 0.3 0.0 0.3 122.0 0.0 0.2 0.3 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 104.3;Muller glia cells: 100.3" "Cancer enhanced" "Detected in all" "melanoma: 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.8" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.8" "Cell line enhanced" "Detected in many" "AN3-CA: 183.5;HEL: 185.7;K-562: 258.0;SK-MEL-30: 189.3;WM-115: 246.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 43.3 63.1 29.1 38.9 29.9 16.8 38.3 36.1 35.2 21.7 30.5 27.0 17.8 44.4 43.4 15.5 23.4 28.8 51.0 31.6 37.7 92.3 21.0 39.8 72.7 31.4 30.8 97.8 26.2 18.0 20.0 46.6 29.7 33.0 13.4 137.8 20.4 25.6 14.3 16.9 25.2 34.2 29.7 79.7 41.8 28.5 32.4 39.3 23.9 19.5 69.6 48.4 19.5 28.0 0.2 0.4 138.8 183.5 48.9 44.7 0.2 7.9 7.5 4.9 7.9 0.9 15.3 16.3 5.5 16.9 0.8 2.3 10.3 16.1 4.2 18.3 28.9 185.7 0.4 2.7 60.7 10.7 68.0 41.7 16.0 20.3 5.6 48.9 22.1 23.8 258.0 0.3 7.9 1.7 24.4 44.8 66.1 7.0 18.0 0.0 46.2 6.7 31.9 23.4 118.9 56.6 1.1 7.4 189.3 41.4 0.2 1.1 13.9 65.3 32.0 0.6 17.8 0.1 0.2 22.9 35.2 36.3 246.7 1.7 0.2 3.2 12.7 0.0 15.8 9.6 26.1 13.8 1.2 12.2 15.0 9.2 0.5 19.3 0.2 0.1 48.8 8.9 29.1 29.9 36.1 35.2 31.6 37.7 31.4 30.8 29.7 29.7 32.4 28.0 52.2 3.2 8.3 25.5 12.5 6.1 9.1 26.9 19.4 55.0 7.9 8.6 17.1 12.8 15.6 16.5 31.3 2.6 17.5 0.7 7.9 17.2 4.3 9.7 11.6 43.9 0.0 22.1 13.5 104.3 0.2 11.3 20.9 15.9 34.2 77.3 59.6 6.7 5.8 20.2 6.9 0.4 28.5 5.1 8.2 14.3 77.3 3.8 30.2 13.1 3.0 100.3 26.8 59.8 2.7 45.3 0.2 74.4 21.0 11.6 0.3 1.0 17.9 66.7 52.6 9.9 41.2 1.0 6.0 5.7 5.4 0.8 27.1 30.5 0.8 32.5 TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 80.5" "Cell type enhanced" "Detected in many" "Ductal cells: 53.1;Hepatocytes: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 630.3;hTCEpi: 401.9;hTERT-HME1: 461.8;SK-MEL-30: 615.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA015272: AB_1858269, HPA055442: AB_2682818" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.25e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.70e-4)" "prognostic unfavorable (6.75e-5)" "unprognostic (1.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.07e-13)" "unprognostic (7.62e-2)" "unprognostic (2.79e-2)" "unprognostic (2.31e-1)" "unprognostic (4.05e-3)" 8.0 16.4 5.6 4.0 5.4 16.1 7.8 6.0 6.7 4.4 6.5 4.4 1.3 2.9 3.0 20.5 2.2 2.6 4.0 5.1 6.5 9.9 80.5 15.4 6.5 5.5 5.5 3.2 17.3 13.3 15.2 8.4 5.6 7.8 2.2 2.7 10.4 3.0 1.8 13.6 5.3 1.8 4.4 12.1 10.2 1.4 6.7 5.6 38.2 0.5 5.9 4.8 5.3 4.4 80.9 41.6 5.1 11.9 13.7 17.9 33.7 23.9 65.8 23.0 47.5 86.7 40.0 35.3 22.2 22.5 102.3 62.6 22.6 107.7 21.4 12.4 16.2 27.5 8.9 144.2 630.3 71.5 12.7 73.3 401.9 43.5 461.8 16.2 45.1 86.1 97.3 155.2 2.3 77.3 4.2 87.0 11.8 122.8 133.0 15.2 7.1 77.1 27.0 33.3 14.7 23.0 5.6 192.2 615.5 7.2 55.7 185.6 24.6 11.7 20.6 0.3 36.2 52.3 73.9 63.5 10.5 61.4 43.6 5.1 6.4 1.4 13.2 4.9 9.4 21.0 12.3 15.3 6.7 13.8 13.7 9.8 4.4 10.2 2.6 2.8 9.7 7.8 5.6 5.4 6.0 6.7 5.1 6.5 5.5 5.5 5.6 4.4 6.7 4.4 7.9 3.2 1.5 0.3 9.3 6.8 10.9 20.3 3.4 6.8 12.7 8.3 1.6 11.5 8.5 1.8 4.2 14.1 4.0 3.4 0.0 53.1 0.0 0.2 1.6 15.8 1.2 5.7 2.2 22.7 6.4 3.9 0.0 2.6 5.1 0.5 6.8 38.4 6.4 0.0 3.1 8.8 6.1 3.3 4.4 0.0 1.8 3.0 7.2 0.0 4.2 1.0 14.4 1.0 0.6 24.0 1.9 1.5 10.0 12.2 0.0 0.1 2.9 7.0 6.6 6.5 6.9 2.4 3.1 4.0 5.4 7.1 5.7 3.5 2.2 6.7 TRIM29 "ATDC, FLJ36085" ENSG00000137699 "Tripartite motif containing 29" Q14134 11 120111286-120185529 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 600.1;skin 1: 551.2;vagina: 269.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 272.0;Basal squamous epithelial cells: 250.4;Late spermatids: 150.3;Squamous epithelial cells: 552.9;Suprabasal keratinocytes: 460.6;Urothelial cells: 159.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 93.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 399.9;HBEC3-KT: 107.5;hTCEpi: 476.0;RT4: 190.5;SiHa: 268.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 4.0" "HPA020053, HPA074841" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA020053: AB_1858280, HPA074841: " "unprognostic (1.10e-1)" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (2.88e-4)" "unprognostic (9.79e-3)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (5.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.37e-2)" "unprognostic (4.29e-3)" "prognostic favorable (4.93e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.15e-2)" 2.5 1.0 0.1 0.4 0.2 0.4 41.7 0.0 0.4 133.8 1.6 3.0 1.7 2.6 4.8 600.1 17.4 3.5 0.4 0.3 0.0 1.7 1.8 3.7 0.0 1.8 0.6 0.4 1.0 0.0 8.1 30.7 1.8 31.4 2.6 0.3 131.5 23.7 2.2 551.2 1.0 1.5 2.6 0.3 1.4 2.7 0.0 19.9 0.4 0.2 107.2 55.8 269.1 0.6 34.4 2.5 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.2 0.1 0.8 25.6 0.2 3.9 0.2 0.5 399.9 0.0 107.5 0.0 0.1 0.0 0.2 25.4 0.4 0.0 0.2 0.5 0.0 476.0 0.0 2.6 0.0 0.0 0.0 0.2 0.7 0.0 4.4 0.0 0.0 0.1 11.4 0.1 0.0 0.3 0.0 0.3 190.5 1.3 5.9 268.3 35.2 0.1 0.2 1.9 0.0 0.4 0.1 2.1 0.2 0.1 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.3 0.0 1.8 0.6 1.8 2.6 0.0 0.6 0.5 0.0 1.5 3.3 0.2 272.0 106.1 76.4 250.4 0.0 9.5 58.8 1.2 1.5 39.2 0.0 0.0 41.0 0.2 11.3 0.0 5.0 28.1 8.7 0.8 3.4 2.4 0.0 0.5 4.3 7.1 5.6 1.1 3.6 1.3 0.0 0.0 0.4 5.0 0.0 0.1 2.1 12.2 0.0 30.3 150.3 0.6 1.4 23.2 1.0 0.0 0.0 0.0 0.0 0.1 57.1 11.3 0.0 0.0 66.0 0.2 0.6 64.6 0.0 0.0 0.1 4.9 0.8 2.6 552.9 460.6 24.8 2.4 0.1 3.7 159.3 TRIM55 "MURF-2, RNF29" ENSG00000147573 "Tripartite motif containing 55" Q9BYV6 8 66126896-66175485 "Predicted intracellular proteins, Predicted membrane proteins" "Muscle protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 61.8;liver: 37.9;skeletal muscle: 29.6;tongue: 33.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 108.9;Endometrial ciliated cells: 64.7;Hepatocytes: 30.4;Skeletal myocytes: 31.0;Spermatocytes: 23.8" "Group enriched" "Detected in some" 10 "liver cancer: 12.3;renal cancer: 5.8" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "LHCN-M2: 426.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038793, HPA053691" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" Cytosol "HPA038793: AB_10673289, HPA053691: AB_2682231" "unprognostic (5.44e-3)" "unprognostic (1.25e-2)" "unprognostic (5.93e-3)" "unprognostic (4.07e-2)" "unprognostic (6.83e-3)" "unprognostic (3.77e-3)" "unprognostic (8.31e-2)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (1.50e-1)" "unprognostic (5.18e-2)" "unprognostic (2.10e-2)" "unprognostic (9.51e-2)" "unprognostic (1.16e-2)" "unprognostic (1.77e-3)" 1.4 0.0 0.1 0.1 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.1 0.1 3.5 0.8 5.3 0.1 61.8 0.0 0.0 4.8 37.9 0.2 0.0 0.1 0.6 0.0 0.2 0.2 0.4 0.0 0.3 0.7 0.1 0.0 1.3 0.2 29.6 0.4 0.1 0.1 0.0 0.1 0.0 7.3 0.0 0.2 0.3 33.7 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.0 7.2 0.1 0.3 0.1 0.0 0.4 0.5 0.6 0.0 60.5 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.2 426.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 18.7 1.5 27.6 0.0 2.4 0.0 0.0 0.1 0.0 91.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.1 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.6 0.0 0.1 2.8 0.0 0.0 0.1 0.0 108.9 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 11.8 64.7 0.2 1.2 0.0 0.0 0.2 0.0 0.1 3.8 0.0 3.5 0.0 0.0 0.7 30.4 0.1 0.0 1.5 0.0 0.0 1.3 0.0 6.4 0.9 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.4 0.2 0.0 0.0 7.4 15.4 0.0 6.6 31.0 2.9 23.8 1.2 0.0 0.0 3.8 0.3 0.0 0.0 0.3 TRIM59 "Mrf1, RNF104, TRIM57, TSBF1" ENSG00000213186 "Tripartite motif containing 59" Q8IWR1 3 160432445-160485773 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 68.4" "Cell type enriched" "Detected in many" 12 "Oligodendrocytes: 391.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017750 Uncertain Approved "Rods & Rings" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Rods & Rings" "HPA017750: AB_1858312" "unprognostic (3.74e-1)" "prognostic favorable (4.36e-4)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-1)" "unprognostic (8.00e-4)" "unprognostic (1.88e-2)" "unprognostic (2.02e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.02e-3)" "unprognostic (2.44e-11)" "unprognostic (7.92e-2)" "unprognostic (2.42e-1)" "unprognostic (4.03e-2)" "unprognostic (5.91e-3)" 0.7 0.8 9.0 5.1 38.8 17.6 2.1 18.0 20.4 1.4 0.0 2.7 2.8 3.0 0.9 4.9 2.0 2.7 0.8 12.3 15.2 1.2 1.0 2.0 12.1 19.4 23.6 1.3 1.5 1.8 1.2 2.0 19.9 2.0 2.6 1.4 1.7 1.0 1.2 5.4 2.9 2.8 9.3 5.1 2.5 8.7 24.6 13.6 2.0 0.1 12.1 3.1 2.2 68.4 20.4 15.8 19.8 1.3 7.8 10.6 26.0 31.5 27.3 38.5 36.9 1.9 34.8 54.5 22.9 23.7 12.1 34.1 0.0 12.9 50.7 49.1 19.2 2.0 5.4 2.4 10.9 24.3 3.2 9.0 3.8 18.7 13.4 23.6 27.1 8.0 25.8 22.6 36.7 21.9 15.0 1.9 52.5 13.2 26.1 20.7 17.2 24.6 13.8 6.6 13.0 2.8 9.0 26.3 0.7 26.5 31.2 22.4 20.9 2.8 8.9 4.5 3.1 37.0 14.5 13.4 3.4 31.0 3.1 29.1 2.8 5.4 10.9 3.1 12.7 10.4 17.9 15.0 4.5 9.3 12.0 14.5 2.2 12.4 1.5 6.7 22.0 3.7 9.0 38.8 18.0 20.4 12.3 15.2 19.4 23.6 19.9 9.3 24.6 68.4 0.6 0.0 6.5 0.3 7.8 4.8 4.7 2.1 3.4 0.4 2.8 1.8 2.5 2.8 1.4 1.8 6.2 7.2 6.1 1.2 0.0 2.0 31.2 1.9 2.1 2.5 10.8 29.5 0.4 2.0 11.7 2.1 5.1 2.9 1.3 10.1 2.2 0.1 2.9 0.0 0.5 2.9 2.0 2.2 2.3 12.5 0.3 1.8 3.6 0.0 2.1 0.5 3.1 0.0 391.8 1.9 2.8 0.7 6.4 3.3 1.2 2.3 2.1 1.7 0.0 2.4 2.7 14.0 15.1 5.6 4.4 2.5 10.9 2.7 4.8 3.6 TRIM69 "RNF36, Trif, TRIMLESS" ENSG00000185880 "Tripartite motif containing 69" Q86WT6 15 44728988-44767829 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 35.0" "Cell type enhanced" "Detected in all" "Early spermatids: 213.2;Late spermatids: 93.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "T-reg: 4.2" "Lineage enriched" "Detected in single" 7 "T-cells: 4.2" "Cell line enhanced" "Detected in some" "Karpas-707: 2.4;U-266/70: 8.2;U-266/84: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA028894 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA028894: AB_10603136" "unprognostic (4.82e-3)" "unprognostic (1.23e-2)" "unprognostic (4.10e-1)" "unprognostic (2.01e-1)" "unprognostic (1.75e-2)" "unprognostic (4.20e-1)" "unprognostic (9.27e-2)" "unprognostic (4.95e-2)" "unprognostic (6.49e-2)" "unprognostic (3.53e-3)" "unprognostic (1.38e-1)" "unprognostic (3.72e-2)" "prognostic favorable (2.26e-5)" "unprognostic (4.79e-2)" "unprognostic (1.82e-1)" "unprognostic (1.91e-2)" "unprognostic (1.49e-2)" 0.8 0.8 5.2 0.4 5.2 0.2 0.8 4.7 7.1 0.9 4.5 1.2 0.4 0.6 0.4 0.7 0.8 0.5 2.8 5.0 5.1 1.6 1.5 1.3 0.9 5.2 5.0 0.8 0.4 0.3 1.5 0.2 5.1 0.8 0.5 0.6 0.8 0.2 5.9 1.0 1.3 0.6 5.0 2.4 0.7 35.0 5.0 0.5 0.6 6.0 1.2 0.7 0.8 5.4 0.1 0.1 0.2 0.6 0.2 0.7 0.0 0.1 0.3 0.8 1.3 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 1.7 0.0 0.2 0.1 0.0 0.7 0.0 0.1 0.9 0.6 0.1 0.1 1.1 0.2 0.7 0.0 2.4 0.2 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.2 8.2 2.3 1.4 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.6 0.6 0.8 0.9 0.0 0.0 0.2 0.6 0.1 0.0 0.2 0.0 4.2 0.1 5.2 5.2 4.7 7.1 5.0 5.1 5.2 5.0 5.1 5.0 5.0 5.4 41.8 6.4 5.1 9.4 22.1 21.3 21.3 8.0 12.0 10.8 9.3 9.1 60.2 8.6 11.0 9.2 4.2 6.1 20.4 16.5 41.1 42.1 213.2 9.0 12.2 22.2 4.2 5.7 16.0 16.0 4.2 17.8 13.7 10.6 14.0 10.5 11.4 5.1 36.3 23.5 9.8 7.5 8.2 25.4 39.7 93.9 9.3 22.6 12.4 1.0 52.7 21.2 20.6 9.5 1.7 14.8 13.4 11.7 21.9 11.4 18.6 27.0 8.8 4.2 6.6 27.0 19.7 78.8 1.7 25.0 41.2 1.5 25.6 5.1 7.0 52.5 TRIM7 "GNIP, RNF90" ENSG00000146054 "Tripartite motif containing 7" Q9C029 5 181193924-181205293 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 193.3;tongue: 51.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 17.8;Cardiomyocytes: 40.1;Squamous epithelial cells: 39.6;Suprabasal keratinocytes: 28.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 16.4;HDLM-2: 35.0;PC-3: 18.8;TIME: 16.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039213 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 37: Myocytes - Muscle contraction" Vesicles "Nucleoplasm, Cytosol" "HPA039213: AB_10795173" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (5.20e-2)" "unprognostic (1.10e-2)" "unprognostic (6.85e-2)" "unprognostic (1.80e-2)" "unprognostic (3.89e-4)" "unprognostic (3.45e-2)" "unprognostic (3.72e-1)" "unprognostic (1.64e-1)" "unprognostic (3.48e-2)" "unprognostic (1.97e-1)" "unprognostic (7.16e-3)" "unprognostic (1.26e-1)" "unprognostic (3.90e-2)" "unprognostic (6.17e-2)" "unprognostic (1.15e-2)" 2.1 1.5 1.2 0.4 1.0 0.4 2.1 10.5 3.0 5.5 0.4 1.9 0.3 1.3 3.1 27.0 2.2 0.2 8.5 0.9 1.7 3.9 0.6 2.6 0.4 3.1 2.9 1.5 4.8 2.7 5.5 0.3 2.8 2.8 0.5 1.6 7.3 0.6 193.3 28.7 1.3 0.6 1.3 1.4 2.2 1.3 2.0 0.4 6.3 51.0 2.1 2.2 9.5 1.3 9.0 4.4 0.1 0.5 0.7 0.8 0.2 1.9 0.0 0.7 1.8 0.4 12.0 0.6 6.1 2.6 3.7 16.4 4.8 13.8 0.2 35.0 1.8 0.9 12.2 0.2 2.2 0.0 2.0 0.1 10.5 0.4 6.7 2.7 3.9 1.6 0.5 2.0 0.4 1.3 0.5 0.3 0.0 14.5 18.8 0.4 6.0 1.4 4.9 0.0 0.4 1.1 4.2 0.2 6.5 0.2 1.0 0.4 16.0 0.2 3.4 0.6 6.3 2.8 0.4 1.0 0.5 0.7 1.5 0.0 1.7 0.0 0.4 0.7 0.7 0.1 0.4 0.4 0.3 0.2 0.7 0.5 0.0 0.1 0.5 0.2 0.9 0.3 1.2 1.0 10.5 3.0 0.9 1.7 3.1 2.9 2.8 1.3 2.0 1.3 7.3 0.0 1.1 0.0 1.0 17.8 4.3 11.1 12.0 6.2 0.8 1.5 40.1 0.0 6.3 3.7 0.0 0.1 0.8 5.9 5.9 0.7 0.9 0.2 0.3 4.6 0.0 0.0 1.3 2.4 0.7 4.8 11.2 0.7 0.0 0.1 5.7 0.4 1.1 0.0 3.9 3.3 2.0 6.0 2.8 0.0 0.9 2.9 1.8 0.0 5.7 0.6 1.0 2.0 0.1 5.0 6.5 1.5 0.1 2.5 0.0 1.5 2.9 2.9 13.1 17.3 5.8 1.5 0.4 39.6 28.4 0.0 1.4 0.1 3.4 5.3 TRIP13 16E1BP ENSG00000071539 "Thyroid hormone receptor interactor 13" Q15645 5 892884-919357 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 29.9" "Cell type enhanced" "Detected in many" "Early spermatids: 115.4;Late spermatids: 206.9;Respiratory ciliated cells: 79.9;Spermatocytes: 86.4;Spermatogonia: 70.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005727, HPA053093" Enhanced Approved Nucleoplasm NA NA 78000 "Cluster 40: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA005727: AB_10603220, HPA053093: AB_2682042" "unprognostic (1.65e-2)" "unprognostic (1.65e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (3.93e-4)" "unprognostic (2.34e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (4.44e-3)" "unprognostic (1.73e-3)" "prognostic favorable (1.39e-4)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.04e-2)" "unprognostic (1.99e-1)" "unprognostic (1.31e-1)" "unprognostic (3.34e-1)" 1.4 0.7 2.0 4.4 2.1 6.0 2.7 0.9 1.8 1.5 1.0 3.8 3.5 1.8 0.6 4.6 6.7 0.7 0.4 1.6 1.5 1.1 0.8 1.3 7.1 1.3 2.0 2.0 1.3 0.2 1.6 3.3 1.4 0.8 5.7 0.5 1.0 0.4 0.6 2.3 3.6 3.5 1.1 1.9 1.7 29.9 1.9 9.3 0.5 0.3 8.4 1.9 1.7 1.2 67.5 73.9 46.6 69.6 4.3 10.1 51.8 68.6 33.1 103.4 96.7 72.2 43.4 59.1 48.7 39.5 90.1 48.7 100.3 47.6 129.1 91.0 83.7 40.6 136.4 52.3 1.1 67.3 23.9 4.7 3.6 87.0 37.3 10.7 51.5 45.9 61.7 50.2 71.7 45.7 67.6 60.6 53.0 37.7 69.4 38.8 87.3 113.0 29.3 34.2 47.9 49.0 103.1 38.2 20.8 40.2 71.3 32.0 26.4 55.6 70.4 46.5 79.0 31.9 68.9 64.6 34.2 79.3 63.1 0.0 0.0 0.0 0.4 0.0 0.2 1.1 0.6 0.7 0.1 1.2 0.2 0.1 0.0 1.6 0.1 1.0 2.1 0.4 2.0 2.1 0.9 1.8 1.6 1.5 1.3 2.0 1.4 1.1 1.9 1.2 0.7 0.0 1.1 0.3 4.3 3.4 3.5 7.3 4.0 0.9 2.2 1.8 0.3 0.0 5.0 0.0 0.0 8.6 0.7 2.2 0.0 3.0 115.4 29.3 2.1 2.5 4.2 14.3 1.3 2.0 25.2 3.4 1.5 3.8 5.7 9.8 2.2 0.4 7.3 3.3 0.5 3.0 4.1 1.3 4.2 206.9 2.1 1.7 0.0 0.0 1.1 0.7 0.0 0.0 0.4 2.2 1.8 2.2 18.1 2.8 0.5 1.2 79.9 0.9 6.6 2.5 5.2 86.4 70.1 7.6 1.4 3.4 3.2 2.7 5.1 3.3 TRIQK "C8orf83, DKFZp779L1068, LOC286144, PRO0845" ENSG00000205133 "Triple QxxK/R motif containing" Q629K1 8 92883532-93017673 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 32.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.47e-3)" "unprognostic (3.09e-1)" "unprognostic (6.03e-3)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (5.13e-2)" "unprognostic (7.78e-2)" "unprognostic (2.50e-1)" "unprognostic (2.31e-1)" "unprognostic (1.56e-1)" "unprognostic (2.52e-1)" "unprognostic (1.79e-1)" "unprognostic (5.11e-3)" "unprognostic (9.23e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-2)" 12.8 21.9 12.3 7.7 15.7 14.5 14.5 18.6 14.9 19.4 10.5 20.7 12.4 12.5 9.7 9.8 15.7 22.9 20.1 13.7 13.5 19.4 31.3 17.0 5.3 13.4 12.6 19.6 18.0 20.6 10.7 19.6 14.0 18.1 21.0 12.4 11.1 10.2 2.4 5.7 12.1 11.4 14.2 13.2 17.5 6.5 13.5 7.3 23.4 5.6 5.2 15.5 7.9 17.0 7.4 9.2 19.8 7.0 27.1 42.8 6.6 26.4 28.4 14.7 20.9 1.3 22.9 0.0 31.6 24.9 9.8 11.9 16.1 15.9 23.7 0.0 7.6 28.9 10.1 15.6 22.9 8.1 24.0 32.0 35.4 8.0 27.1 33.3 15.7 16.3 5.6 16.7 21.3 19.7 13.1 6.3 6.8 31.3 33.8 0.0 20.5 9.6 27.8 9.1 11.4 16.0 10.0 3.9 25.6 16.3 27.2 7.1 20.5 21.8 6.7 38.3 8.3 5.8 0.0 0.0 33.8 0.1 22.5 0.9 17.0 15.9 0.1 18.8 8.1 2.8 0.9 0.7 9.4 1.9 0.0 0.0 14.6 2.0 32.9 2.5 0.2 4.7 12.3 15.7 18.6 14.9 13.7 13.5 13.4 12.6 14.0 14.2 13.5 17.0 19.0 19.2 17.9 21.9 4.0 15.0 21.4 17.1 22.8 18.9 17.7 12.4 13.8 25.8 14.1 16.5 6.2 7.3 2.1 16.2 50.9 14.8 7.0 21.3 27.7 17.8 19.2 6.7 36.8 16.4 23.8 23.5 20.9 24.5 2.5 11.7 17.2 18.3 11.9 6.7 43.6 35.6 12.2 20.0 13.6 8.0 16.4 18.5 23.2 31.9 24.3 22.8 3.1 34.7 56.3 12.5 14.0 21.8 1.0 22.2 17.0 39.1 29.5 6.3 32.9 18.4 18.2 12.1 5.3 12.3 8.4 3.7 3.3 21.6 20.0 22.6 TROAP TASTIN ENSG00000135451 "Trophinin associated protein" Q12815 12 49323236-49331731 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.0;lymphoid tissue: 36.7;testis: 29.1" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Erythroid cells: 75.6;Late spermatids: 70.2;Spermatocytes: 29.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 8.6" "Lineage enriched" "Detected in many" 4 "T-cells: 8.6" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA044102 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "HPA044102: AB_10963691" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" "unprognostic (1.09e-1)" "unprognostic (3.92e-3)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (3.43e-3)" "unprognostic (2.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.08e-3)" "unprognostic (3.51e-2)" "unprognostic (0.00e+0)" "unprognostic (1.80e-1)" "unprognostic (1.54e-1)" "unprognostic (1.92e-1)" "unprognostic (5.17e-2)" 1.3 1.5 0.2 7.3 0.3 51.0 1.4 0.2 0.7 2.8 0.2 6.7 9.0 1.2 0.5 13.5 0.7 0.8 0.8 0.2 0.2 0.9 1.6 2.4 11.2 0.4 0.2 0.8 0.8 0.7 0.4 5.1 0.3 0.9 9.2 0.6 2.5 0.4 0.3 7.7 7.6 2.8 0.1 7.0 5.4 29.1 0.5 36.7 0.8 0.3 14.5 1.9 5.3 0.3 95.9 73.9 92.4 69.7 2.8 6.2 71.2 45.4 43.4 129.5 73.1 163.7 73.5 64.6 21.9 33.7 70.7 74.6 70.4 44.0 75.7 51.9 101.8 90.9 120.4 53.7 1.9 66.5 93.8 1.5 6.0 86.9 59.8 21.1 75.1 68.0 57.2 108.9 52.7 123.0 122.9 101.8 43.4 269.3 110.2 62.5 78.6 83.9 31.7 35.0 59.9 41.0 56.0 107.4 32.7 53.6 88.2 50.1 25.0 33.5 91.2 69.4 124.8 58.3 68.8 83.0 32.3 73.8 38.4 0.2 0.0 0.1 0.1 0.0 0.2 1.4 2.1 2.3 0.3 1.4 0.1 0.5 0.0 2.0 0.1 0.0 8.6 0.5 0.2 0.3 0.2 0.7 0.2 0.2 0.4 0.2 0.3 0.1 0.5 0.3 0.1 0.0 0.0 0.0 4.6 3.8 1.5 2.8 1.2 0.6 2.1 2.8 0.5 0.0 1.8 0.0 0.0 14.1 1.0 3.7 0.0 0.7 71.5 1.9 1.3 1.9 1.2 75.6 0.0 0.7 23.6 3.3 10.2 2.7 0.0 16.0 5.7 1.1 15.7 0.0 0.0 7.9 10.2 6.7 3.7 70.2 1.8 4.0 1.8 0.0 0.9 0.0 6.2 0.0 0.0 0.8 1.8 0.4 17.0 1.1 0.7 0.1 0.2 0.4 0.0 0.7 3.5 29.1 9.3 15.6 2.0 4.0 2.5 0.9 12.7 3.6 TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001061-31161273 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 9.4;skin 1: 4.1" "Group enriched" "Detected in some" 7 "Bipolar cells: 627.4;Melanocytes: 158.3" "Cancer enriched" "Detected in single" 179 "melanoma: 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 112 "SK-MEL-30: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: AB_2669090, HPA071139: " "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (9.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-3)" "unprognostic (2.83e-1)" "unprognostic (2.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (7.84e-2)" "unprognostic (6.20e-4)" "unprognostic (1.48e-1)" "unprognostic (2.63e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.4 0.1 0.0 0.0 4.1 0.0 0.0 0.5 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.2 0.2 0.4 0.3 0.5 0.3 0.5 0.0 0.0 0.0 0.7 0.0 4.2 0.0 0.0 0.0 627.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 50.5 0.1 0.1 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 13.5 0.8 0.0 0.0 0.0 1.0 6.3 0.0 0.0 158.3 0.0 0.0 11.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 22.2 0.0 0.1 0.1 10.1 4.4 1.8 1.0 1.0 0.0 0.0 0.0 0.1 TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.2;Hepatocytes: 81.7;Intestinal goblet cells: 114.8;Paneth cells: 77.1;Undifferentiated cells: 88.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Cell line enhanced" "Detected in many" "OE19: 32.7;RT4: 60.8;SK-BR-3: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA041169: AB_2677343" "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favorable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" 10.8 6.1 5.8 6.1 5.4 4.6 13.5 8.5 7.0 11.5 4.8 46.1 25.3 9.9 2.5 13.1 9.2 7.4 23.0 5.9 4.5 22.8 15.4 16.0 1.8 6.2 7.4 3.3 10.1 3.7 5.6 5.3 6.9 35.7 12.9 1.3 27.3 6.2 14.0 26.6 22.9 3.4 4.2 5.5 20.6 5.4 6.6 1.0 17.3 5.3 1.9 13.7 14.4 5.1 11.9 9.0 2.1 9.5 7.7 6.6 6.6 10.0 6.0 2.7 3.7 6.1 18.7 0.4 2.7 6.8 3.6 15.7 1.3 3.0 1.0 0.2 3.4 1.9 4.0 3.7 6.6 0.3 11.7 9.3 13.6 5.3 2.6 3.3 4.6 1.0 4.9 2.1 6.9 17.4 0.8 0.9 1.0 32.7 13.3 4.1 2.0 0.6 4.6 60.8 0.8 2.2 4.1 38.6 2.2 0.7 22.6 3.7 11.8 14.4 7.8 7.9 0.2 3.9 4.3 0.4 7.9 7.4 5.3 2.2 4.3 0.7 0.3 2.5 0.2 0.5 0.2 0.2 3.3 0.5 0.3 0.3 2.8 0.5 1.0 3.1 0.2 1.4 5.8 5.4 8.5 7.0 5.9 4.5 6.2 7.4 6.9 4.2 6.6 5.1 12.8 32.1 2.6 9.8 3.5 12.5 15.3 9.9 9.1 2.0 19.0 14.6 16.7 17.2 12.3 14.7 0.0 6.6 0.2 179.2 19.6 7.9 2.9 17.5 8.2 11.7 21.7 0.0 5.4 18.5 6.8 6.0 71.4 36.2 5.7 2.9 11.4 81.7 19.9 0.0 8.5 114.8 14.2 9.8 19.0 3.1 6.8 8.5 39.2 9.4 12.8 6.7 0.0 3.5 0.9 32.9 77.1 7.2 7.6 35.5 55.3 3.8 8.9 2.6 32.9 2.2 8.5 6.1 15.7 8.4 11.5 3.4 1.9 4.1 88.9 33.1 TRPM6 "CHAK2, FLJ22628, HOMG, HSH" ENSG00000119121 "Transient receptor potential cation channel subfamily M member 6" Q9BX84 9 74722495-74888094 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 6.6;intestine: 16.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 128.9;Glandular and luminal cells: 36.5;Microglial cells: 39.4;Oligodendrocytes: 81.1;Proximal enterocytes: 23.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 23.1;neutrophil: 7.5" "Lineage enriched" "Detected in single" 41 "granulocytes: 23.1" "Cell line enhanced" "Detected in some" "BEWO: 3.8;HeLa: 2.4;Karpas-707: 1.3;RT4: 3.8;U-266/70: 1.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "unprognostic (7.80e-2)" "unprognostic (9.20e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (5.72e-4)" "unprognostic (1.58e-1)" "unprognostic (1.71e-2)" "unprognostic (8.10e-2)" "unprognostic (7.54e-2)" "unprognostic (1.89e-2)" "unprognostic (2.11e-2)" 0.6 0.0 2.1 0.6 3.5 2.6 0.6 3.0 2.4 0.3 0.2 13.2 7.0 0.3 0.2 0.3 0.2 0.3 0.2 1.6 2.8 1.9 0.1 0.3 0.3 4.2 3.4 0.0 0.1 1.4 0.5 0.3 4.1 0.5 16.6 0.4 0.3 0.1 0.1 0.7 7.9 0.5 2.7 0.5 0.2 1.4 3.1 0.4 0.2 0.1 0.3 0.4 0.3 6.6 0.0 0.8 0.1 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 1.0 0.1 0.3 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.1 0.1 2.4 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.1 0.0 1.4 0.0 0.1 0.0 0.1 0.1 23.1 0.1 2.4 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.1 7.5 0.5 0.2 0.3 0.0 0.1 2.1 3.5 3.0 2.4 1.6 2.8 4.2 3.4 4.1 2.7 3.1 6.6 3.3 0.0 1.7 1.0 0.3 0.1 1.9 0.3 2.2 0.3 0.2 0.4 0.9 0.0 1.3 3.7 0.0 0.2 0.2 128.9 0.0 0.0 4.0 11.3 3.4 3.2 3.6 0.0 1.3 0.0 0.1 0.3 0.0 36.5 0.0 0.1 3.3 0.1 0.0 0.0 0.5 3.0 0.0 0.3 0.6 0.9 0.0 0.4 0.0 39.4 0.0 0.3 0.0 0.5 81.1 0.0 13.8 0.4 0.1 1.3 23.3 0.0 0.8 2.7 0.0 0.7 0.4 1.6 2.4 0.5 1.0 0.1 0.5 0.2 7.5 0.8 TRPS1 "GC79, LGCR" ENSG00000104447 "Transcriptional repressor GATA binding 1" Q9UHF7 8 115408496-115809673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 60.8" "Cell type enhanced" "Detected in many" "Astrocytes: 758.7;Breast glandular cells: 243.2;Oligodendrocyte precursor cells: 280.5;Oligodendrocytes: 294.0" "Cancer enriched" "Detected in many" 8 "breast cancer: 49.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 47.4;SK-BR-3: 78.1;T-47d: 244.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060380, HPA071767" Enhanced Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA060380: AB_2684270, HPA071767: AB_2732185" "unprognostic (4.34e-2)" "unprognostic (4.65e-2)" "unprognostic (1.73e-2)" "unprognostic (2.57e-1)" "unprognostic (1.87e-1)" "prognostic favorable (9.42e-4)" "unprognostic (2.23e-3)" "unprognostic (2.08e-1)" "unprognostic (9.31e-2)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (3.02e-1)" "unprognostic (2.17e-2)" "unprognostic (1.93e-2)" "unprognostic (1.64e-1)" "unprognostic (1.78e-2)" "unprognostic (3.07e-3)" 4.4 3.1 15.5 5.7 14.3 7.6 60.8 10.5 14.7 10.9 10.1 5.9 0.9 9.9 3.4 14.2 5.5 10.0 3.8 17.0 13.5 5.4 2.1 4.7 4.9 32.5 31.5 5.2 1.1 5.3 2.6 2.8 24.2 9.4 2.7 4.1 12.0 8.4 2.6 10.6 2.1 10.6 18.4 4.2 2.7 12.5 27.5 2.4 5.7 3.3 4.0 5.1 14.1 16.3 3.1 0.6 5.9 0.3 5.4 19.8 0.6 4.9 11.3 3.1 5.2 0.5 4.9 2.4 0.0 12.7 2.6 0.1 22.9 4.3 3.5 0.3 6.9 0.1 10.3 0.2 7.2 0.0 0.3 9.5 4.4 8.6 15.8 8.9 2.7 0.3 1.1 37.7 6.0 47.4 0.2 0.0 1.1 1.1 4.8 0.2 0.2 30.0 4.9 0.3 5.2 3.9 2.5 78.1 3.2 2.8 244.8 2.1 0.2 13.7 6.9 4.0 9.7 10.1 0.3 4.5 14.4 0.0 9.2 0.0 4.5 0.0 0.9 1.9 0.9 0.5 1.0 1.0 1.7 0.8 0.9 0.9 0.8 1.0 1.4 0.6 0.5 0.8 15.5 14.3 10.5 14.7 17.0 13.5 32.5 31.5 24.2 18.4 27.5 16.3 10.0 6.4 3.0 758.7 13.3 9.4 20.0 10.3 34.1 9.2 243.2 125.1 4.6 2.8 9.2 18.4 43.8 0.1 18.7 0.1 11.7 2.9 95.0 58.5 35.7 7.5 0.0 5.5 128.3 2.9 0.2 26.8 4.6 63.5 12.7 0.3 3.6 1.1 16.5 0.0 148.2 0.0 8.2 55.2 104.1 163.2 25.1 55.5 21.4 171.4 32.5 10.6 5.2 280.5 294.0 2.7 0.0 28.2 10.1 16.9 0.0 23.7 8.9 35.9 6.6 60.2 28.2 1.8 8.3 73.6 12.5 0.3 25.6 19.5 0.0 11.2 TRPV4 "CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC" ENSG00000111199 "Transient receptor potential cation channel subfamily V member 4" Q9HBA0 12 109783087-109833406 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Charcot-Marie-Tooth disease, Disease variant, Dwarfism, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 50.8;salivary gland: 19.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 17.1;Cholangiocytes: 20.0;Cytotrophoblasts: 20.0;Kupffer cells: 19.6;Respiratory ciliated cells: 28.2;Syncytiotrophoblasts: 21.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 5 "hippocampal formation: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 7.9;BJ hTERT+: 9.5;EFO-21: 7.2;HaCaT: 14.2;HUVEC TERT2: 8.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007150 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA007150: AB_1080393" "unprognostic (2.98e-2)" "unprognostic (1.12e-2)" "unprognostic (2.33e-2)" "unprognostic (4.20e-3)" "unprognostic (6.25e-3)" "unprognostic (1.09e-2)" "unprognostic (7.95e-2)" "unprognostic (2.03e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "prognostic favorable (4.12e-5)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" 1.0 0.8 0.2 0.9 0.3 0.1 1.9 0.7 0.5 2.0 50.8 0.4 0.7 0.6 0.4 10.3 4.7 1.4 0.8 4.2 0.2 14.7 8.6 2.2 0.8 0.5 0.4 0.3 4.4 0.3 2.1 5.2 0.3 6.8 0.3 0.0 19.2 0.8 0.1 7.5 0.4 0.7 0.2 2.8 0.7 0.8 0.8 0.1 0.9 0.0 0.9 1.8 2.2 0.4 2.4 0.2 0.0 0.0 2.0 1.2 7.9 4.2 9.5 1.2 0.3 0.0 6.4 0.0 7.2 5.8 0.0 14.2 1.0 0.0 0.4 0.0 1.8 0.0 0.1 3.7 0.6 0.0 0.0 3.4 2.0 2.7 0.0 0.6 8.7 0.0 0.5 0.0 0.4 5.3 0.0 0.0 1.5 0.0 0.0 0.0 0.5 0.0 0.0 4.9 0.0 0.0 0.3 0.6 2.6 3.5 1.1 0.2 4.5 0.0 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.5 4.2 0.2 0.5 0.4 0.3 0.2 0.8 0.4 0.1 0.0 0.0 0.0 0.7 3.3 8.1 17.1 7.4 0.0 5.1 5.5 1.0 20.0 12.0 11.0 0.0 20.0 0.4 0.0 3.9 2.5 0.2 3.2 1.0 1.4 0.0 0.0 0.3 9.3 5.3 1.2 2.0 1.2 0.0 0.9 0.7 7.7 4.0 0.0 0.4 0.0 6.1 19.6 0.7 0.2 0.9 2.6 7.2 1.9 0.8 0.0 0.0 1.0 0.3 2.0 0.0 0.0 0.0 4.6 0.0 12.5 28.2 0.0 0.0 0.1 1.1 0.3 1.1 4.5 3.8 21.1 0.3 0.2 0.0 3.3 TSEN34 "LENG5, SEN34, SEN34L" ENSG00000170892 "TRNA splicing endonuclease subunit 34" Q9BSV6 19 54189938-54194536 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" Lyase "Disease variant, Neurodegeneration, Pontocerebellar hypoplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 5.0;eosinophil: 1.9;neutrophil: 4.8" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041111, HPA048208" Approved Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA041111: AB_10794263, HPA048208: AB_2680313" "unprognostic (3.24e-2)" "unprognostic (2.95e-2)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (3.48e-2)" "unprognostic (4.82e-2)" "prognostic unfavorable (1.44e-7)" "unprognostic (2.38e-1)" "unprognostic (7.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.04e-3)" "unprognostic (8.98e-2)" "unprognostic (4.55e-3)" "unprognostic (2.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.81e-1)" "unprognostic (1.12e-1)" 28.5 68.2 2.2 1.3 1.8 1.3 29.5 2.4 2.4 38.8 1.8 34.7 1.1 37.1 1.9 41.0 37.8 1.5 26.3 2.1 1.7 39.1 41.3 31.5 1.3 2.2 1.7 47.9 43.0 1.8 36.0 1.3 2.0 36.2 1.3 2.0 34.0 1.9 26.7 40.5 27.7 1.2 1.3 44.1 34.3 45.0 1.7 0.5 30.9 1.8 0.7 38.9 34.2 2.2 3.3 1.7 2.5 3.1 1.3 2.0 3.9 0.6 1.0 0.9 1.7 2.1 1.1 1.1 0.0 0.9 2.5 2.5 2.6 2.3 1.4 1.1 6.2 1.0 1.1 2.0 0.5 1.1 1.1 1.9 1.1 2.0 1.3 0.9 1.3 0.0 1.7 0.9 2.4 1.4 0.4 0.2 1.5 2.9 1.1 1.4 2.6 0.7 3.4 2.4 0.1 1.7 0.0 3.5 3.0 2.5 2.6 3.1 1.1 0.2 2.8 2.7 3.4 1.4 1.9 0.9 2.6 1.3 1.2 5.0 0.6 1.9 0.2 0.5 0.4 0.1 0.3 0.1 0.3 0.4 0.4 0.2 4.8 0.0 0.3 0.4 0.0 0.2 2.2 1.8 2.4 2.4 2.1 1.7 2.2 1.7 2.0 1.3 1.7 2.2 33.1 12.8 27.7 6.8 28.2 73.5 92.0 137.7 67.2 35.4 62.9 60.8 11.8 52.9 60.9 44.1 29.2 102.5 45.4 58.8 95.9 68.7 24.0 39.4 37.0 32.5 76.8 13.7 3.8 59.7 98.2 47.5 19.9 35.3 26.6 47.7 35.7 40.6 57.8 16.8 4.9 103.7 122.1 37.0 53.6 17.2 67.7 45.0 46.2 1.0 51.8 81.9 18.6 6.0 5.9 50.4 55.9 66.5 27.6 79.8 57.8 110.5 70.0 48.9 59.2 38.7 60.8 40.1 77.2 56.7 70.2 111.0 32.8 100.3 66.5 62.3 TSPAN11 ENSG00000110900 "Tetraspanin 11" A1L157 12 30926428-30996602 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 25.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.7;Inhibitory neurons: 5.7;Late spermatids: 10.6;Oligodendrocyte precursor cells: 27.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.2;HSkMC: 22.8;NTERA-2: 18.2;SCLC-21H: 9.7;SH-SY5Y: 18.6;SuSa: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066789 Approved Vesicles NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA066789: AB_2685723" "unprognostic (4.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.38e-3)" "unprognostic (1.18e-2)" "unprognostic (4.51e-1)" "prognostic favorable (5.28e-4)" "unprognostic (4.28e-2)" "prognostic favorable (3.43e-4)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (1.51e-2)" "unprognostic (3.03e-2)" "unprognostic (5.77e-3)" "unprognostic (2.04e-2)" "unprognostic (5.81e-2)" "unprognostic (2.90e-3)" "unprognostic (1.79e-1)" 2.5 2.1 5.5 7.5 5.1 0.0 1.9 9.3 5.0 6.5 0.8 25.9 3.9 1.7 5.8 3.5 1.9 7.1 6.5 5.0 3.9 1.0 0.7 3.4 2.2 4.5 5.7 0.8 1.1 0.1 1.0 0.7 3.7 4.1 8.8 1.4 2.4 4.8 0.4 5.6 9.6 6.4 2.3 2.4 3.8 1.0 6.3 0.8 3.1 1.2 4.1 4.5 3.6 4.8 0.0 0.3 25.2 0.0 0.1 0.3 0.2 0.3 0.8 0.0 0.0 0.0 0.8 0.0 1.4 2.2 0.1 0.6 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.1 22.8 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 18.2 0.0 0.2 0.1 0.1 0.5 0.0 0.1 9.7 18.6 0.2 0.0 0.1 11.2 0.0 0.0 0.0 0.1 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.1 9.3 5.0 5.0 3.9 4.5 5.7 3.7 2.3 6.3 4.8 0.6 0.0 0.0 3.6 0.0 0.8 0.0 0.0 0.0 1.7 0.1 0.0 2.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.5 2.4 3.3 0.0 0.0 1.5 0.0 0.0 4.3 0.0 0.4 0.0 0.2 5.7 0.2 0.1 0.0 5.7 0.0 0.0 0.0 1.7 10.6 4.7 0.2 1.8 1.0 0.0 3.6 0.0 27.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.9 0.5 0.0 0.3 1.1 0.2 0.5 0.1 1.1 0.0 0.2 0.1 0.0 0.1 TSPAN12 "NET-2, TM4SF12" ENSG00000106025 "Tetraspanin 12" O95859 7 120787320-120858402 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Collecting duct cells: 103.0;Distal tubular cells: 189.8;Glandular and luminal cells: 87.5;Proximal tubular cells: 111.1" "Cancer enhanced" "Detected in all" "renal cancer: 44.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 53.0;HUVEC TERT2: 58.3;RH-30: 52.2;RPTEC TERT1: 90.5;RT4: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051570, HPA058244" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Microtubules Vesicles "HPA051570: , HPA058244: AB_2683652" "unprognostic (2.40e-2)" "unprognostic (7.60e-2)" "unprognostic (3.66e-3)" "unprognostic (1.82e-2)" "unprognostic (3.97e-1)" "unprognostic (7.34e-3)" "unprognostic (1.60e-1)" "unprognostic (8.12e-2)" "unprognostic (1.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (9.53e-2)" "unprognostic (7.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.43e-1)" 11.9 65.9 4.1 5.3 4.4 0.4 8.7 5.2 5.2 21.4 2.8 24.0 39.4 10.5 14.9 5.0 10.9 20.4 47.7 3.3 4.7 91.6 35.8 45.8 4.5 8.0 6.2 1.7 17.4 10.7 7.5 20.3 5.2 6.8 20.4 1.8 46.8 22.4 3.3 1.6 42.0 11.9 4.6 28.2 22.1 3.9 8.1 2.7 23.4 5.5 4.3 17.5 4.0 3.6 0.0 1.4 15.1 0.2 3.1 1.0 14.7 0.3 0.6 1.2 5.0 2.5 4.0 0.0 10.4 0.4 1.8 0.2 7.7 1.6 1.9 0.0 53.0 2.8 14.5 2.2 8.1 0.1 2.5 0.3 0.0 0.4 0.3 2.1 58.3 0.0 0.7 1.8 6.8 2.0 0.2 0.4 24.5 11.1 9.4 0.1 52.2 2.0 90.5 65.4 12.5 7.4 0.7 1.3 0.0 20.0 8.0 1.9 2.5 12.3 3.8 0.1 6.5 15.8 0.0 0.2 1.7 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.4 5.2 5.2 3.3 4.7 8.0 6.2 5.2 4.6 8.1 3.6 40.0 118.6 45.0 18.6 1.7 2.5 20.3 1.8 14.8 0.0 19.4 3.8 62.5 64.3 19.9 103.0 0.0 40.5 0.0 18.0 189.8 6.8 0.6 63.4 9.0 38.0 9.6 2.7 1.8 7.2 53.5 10.0 14.8 87.5 2.5 1.8 18.2 32.9 4.1 0.0 2.9 16.9 6.1 0.8 3.6 1.5 4.1 1.5 5.4 3.7 0.0 0.5 0.0 10.1 0.4 4.7 30.5 0.7 2.2 9.1 68.3 111.1 5.7 0.1 0.0 11.6 16.6 0.6 8.9 13.8 2.0 24.2 1.9 9.6 35.5 28.3 TSPAN3 "TM4-A, TM4SF8, TSPAN-3" ENSG00000140391 "Tetraspanin 3" O60637 15 77041404-77083984 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 705.9;Muller glia cells: 508.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "memory B-cell: 481.0;naive B-cell: 488.1;plasmacytoid DC: 313.2" "Group enriched" "Detected in all" 5 "B-cells: 488.1;dendritic cells: 313.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015996 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA015996: AB_1858406" "unprognostic (5.94e-2)" "unprognostic (3.05e-1)" "unprognostic (7.32e-2)" "unprognostic (2.15e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (5.41e-3)" "unprognostic (3.51e-3)" "unprognostic (2.90e-2)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (3.79e-3)" "unprognostic (1.35e-1)" 333.8 143.9 257.2 87.3 248.9 33.3 143.3 253.4 292.4 138.2 288.7 364.2 342.1 130.9 432.8 78.4 249.8 186.2 108.8 247.8 296.3 211.3 87.4 202.1 88.0 250.0 267.7 148.1 140.2 283.4 189.7 111.6 260.2 96.2 386.3 418.6 152.2 187.3 429.1 78.3 349.2 128.3 266.7 84.8 221.2 84.8 282.5 71.6 200.3 374.4 106.9 170.1 67.4 281.3 130.6 347.6 282.8 179.3 484.7 295.8 93.3 203.7 220.2 245.1 265.7 213.5 264.7 126.9 294.8 211.6 234.0 289.0 271.2 139.5 182.9 143.4 410.4 91.0 252.5 204.4 234.5 118.4 64.3 280.9 165.5 135.8 120.1 372.6 304.8 83.1 98.0 109.2 243.3 49.5 105.7 112.1 200.5 414.7 152.4 130.8 351.0 135.3 408.0 73.0 255.0 282.1 139.8 116.9 393.7 269.3 125.0 220.8 292.1 225.7 88.4 138.0 290.7 237.4 346.6 67.1 200.1 173.5 131.9 8.8 51.3 10.4 32.6 69.6 34.1 481.0 16.5 23.9 99.2 488.1 42.6 39.3 4.8 60.3 77.1 313.2 4.6 95.2 257.2 248.9 253.4 292.4 247.8 296.3 250.0 267.7 260.2 266.7 282.5 281.3 76.1 112.2 213.4 69.5 83.8 34.7 77.5 114.6 36.5 247.7 43.6 32.3 98.2 108.7 169.0 68.0 183.5 89.9 41.3 705.9 25.4 250.2 28.5 86.1 63.4 57.6 91.3 19.4 47.8 354.0 35.6 90.8 85.1 41.7 23.4 88.6 53.6 29.5 65.4 127.9 54.3 290.4 97.6 58.0 27.5 57.9 64.3 38.2 72.9 29.0 35.1 508.9 36.0 116.6 32.7 245.1 410.7 51.6 81.2 220.1 364.3 65.5 201.7 185.1 26.3 44.8 189.0 108.0 64.6 34.2 34.2 75.9 19.4 149.5 205.2 381.4 TSPAN5 "NET-4, TM4SF9, Tspan-5" ENSG00000168785 "Tetraspanin 5" P62079 4 98470367-98658611 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 175.4;Excitatory neurons: 362.2;Inhibitory neurons: 248.3;Microglial cells: 195.8;Oligodendrocytes: 587.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 37 "B-cells: 3.0;NK-cells: 3.8;T-cells: 6.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 120.8;BJ hTERT+: 121.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (2.29e-1)" "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" "unprognostic (2.00e-3)" "unprognostic (2.65e-1)" "unprognostic (2.44e-3)" "unprognostic (1.41e-2)" "unprognostic (1.54e-2)" "unprognostic (9.27e-2)" "unprognostic (1.79e-1)" "unprognostic (3.30e-3)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.83e-5)" "prognostic unfavorable (8.56e-4)" "unprognostic (2.15e-1)" "unprognostic (3.23e-3)" "unprognostic (1.23e-1)" 2.7 1.2 32.5 3.8 37.2 10.4 15.4 62.0 42.7 13.5 21.6 6.4 1.5 19.9 29.2 12.9 7.2 5.0 3.2 41.4 33.5 5.1 0.6 4.3 6.7 32.8 30.8 46.4 0.9 4.0 5.1 7.9 34.5 5.3 3.8 28.1 10.8 8.7 3.8 20.0 3.0 16.4 32.4 9.9 8.9 12.6 33.7 8.5 18.5 3.2 9.2 8.8 9.7 47.4 27.8 10.8 11.0 0.7 41.2 120.8 3.7 111.9 121.4 39.4 48.3 9.6 14.6 0.0 1.1 40.2 21.6 7.0 9.6 52.6 87.7 34.3 5.2 16.9 1.5 0.4 42.5 9.5 0.9 70.1 1.6 72.5 89.1 60.5 64.5 11.3 6.6 29.1 95.3 0.7 29.1 0.1 7.2 23.8 49.2 8.8 10.5 4.2 3.5 8.1 77.5 14.8 2.0 35.4 0.2 3.7 1.2 1.4 66.4 82.7 37.4 29.8 39.9 20.0 31.8 0.0 32.4 22.5 28.8 0.0 0.0 0.0 3.3 0.0 3.6 1.3 4.7 4.7 0.1 3.0 2.4 1.6 0.1 3.8 0.0 0.0 6.0 1.1 32.5 37.2 62.0 42.7 41.4 33.5 32.8 30.8 34.5 32.4 33.7 47.4 4.6 22.4 9.1 129.3 5.6 22.0 24.8 9.1 10.8 63.9 30.9 26.0 2.3 0.0 9.3 29.5 27.1 1.0 17.2 1.4 5.9 2.3 69.6 8.5 45.9 19.7 80.9 175.4 362.2 7.1 0.9 26.0 10.2 15.1 2.5 11.6 8.2 0.9 2.3 111.0 248.3 4.6 20.3 3.4 15.4 91.4 46.0 7.1 28.4 195.8 0.3 21.5 39.1 94.5 587.2 25.3 0.5 17.0 9.3 45.9 0.4 0.6 3.7 41.9 6.6 9.7 13.1 10.1 4.1 33.0 57.7 2.9 31.4 79.7 3.8 44.8 TSR2 "DT1P1A10, RP1-112K5.2, WGG1" ENSG00000158526 "TSR2 ribosome maturation factor" Q969E8 X 54440404-54448032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030514 Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytosol" "HPA030514: AB_10603457" "unprognostic (1.05e-1)" "unprognostic (1.80e-2)" "unprognostic (1.77e-2)" "unprognostic (1.58e-2)" "unprognostic (2.64e-2)" "unprognostic (5.91e-2)" "unprognostic (7.15e-3)" "unprognostic (8.29e-2)" "unprognostic (4.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.94e-2)" "unprognostic (6.19e-2)" "prognostic favorable (1.21e-6)" "unprognostic (2.27e-1)" "unprognostic (1.13e-1)" "unprognostic (7.93e-3)" "unprognostic (1.80e-3)" 35.2 45.1 50.9 11.2 49.9 11.9 35.6 43.4 59.4 36.8 39.3 42.2 10.2 34.9 23.0 34.6 32.2 7.7 45.5 46.2 52.9 43.8 36.7 30.4 12.6 48.9 48.0 34.6 30.2 25.0 47.1 14.6 47.3 33.3 13.3 27.4 32.6 16.9 51.7 40.7 31.3 13.2 50.3 32.4 38.8 16.5 50.6 14.9 41.1 18.6 15.8 36.3 35.0 47.8 24.1 26.6 23.9 20.6 19.9 13.0 18.7 22.4 17.5 19.6 17.3 26.2 24.1 23.5 15.8 18.2 35.7 24.9 47.9 28.3 24.8 29.8 26.8 19.3 20.8 19.6 12.5 32.7 19.4 12.9 18.0 26.4 27.1 19.7 13.8 22.9 20.5 16.9 19.3 37.9 27.4 29.9 34.6 23.6 33.0 26.5 38.2 19.6 20.6 18.3 25.9 20.5 42.1 19.9 28.0 38.0 45.4 14.7 21.0 16.2 27.1 38.0 19.9 19.8 32.3 29.7 24.4 27.5 23.2 29.7 16.6 32.0 36.3 23.1 30.0 44.8 34.0 33.6 15.1 46.3 42.6 32.3 10.4 29.7 26.0 16.7 40.8 24.9 50.9 49.9 43.4 59.4 46.2 52.9 48.9 48.0 47.3 50.3 50.6 47.8 39.1 25.6 30.2 1.6 39.8 32.8 43.0 42.7 26.7 61.6 27.4 28.6 49.0 28.6 38.6 35.0 27.1 98.5 36.0 26.3 125.2 43.9 1.2 17.7 23.7 35.6 18.1 18.1 5.7 32.9 71.5 33.8 16.8 22.9 45.0 20.3 31.8 25.2 46.6 57.2 5.6 35.5 61.1 18.2 31.4 2.8 34.8 24.6 40.9 6.5 48.6 85.6 44.3 2.5 6.5 38.1 29.5 45.1 22.3 36.7 32.6 64.6 33.8 67.0 46.0 29.8 38.0 20.5 43.3 25.4 31.7 75.9 37.8 36.2 30.9 33.9 TSSK6 "CT72, FLJ24002, SSTK" ENSG00000178093 "Testis specific serine kinase 6" Q9BXA6 19 19512418-19515548 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "testis: 167.6" "Cell type enriched" "Detected in some" 5 "Late spermatids: 8709.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.4;CACO-2: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.12e-1)" "unprognostic (7.89e-2)" "unprognostic (7.26e-2)" "unprognostic (6.64e-2)" "unprognostic (3.39e-1)" "unprognostic (7.20e-5)" "unprognostic (3.38e-1)" "unprognostic (5.51e-3)" "unprognostic (5.17e-2)" "unprognostic (1.46e-1)" "unprognostic (3.98e-4)" "unprognostic (2.28e-2)" "unprognostic (5.34e-3)" "unprognostic (2.74e-3)" "unprognostic (2.78e-2)" "unprognostic (1.52e-3)" "unprognostic (9.89e-2)" 0.6 0.7 0.4 0.0 0.6 0.1 0.7 0.5 0.5 0.4 0.1 0.7 0.5 0.8 0.0 0.7 0.6 0.0 0.3 0.3 0.2 0.9 1.2 0.4 0.3 0.7 0.6 0.5 1.0 0.0 0.7 0.0 0.7 0.9 0.0 0.0 0.6 0.0 0.3 1.6 1.0 0.0 0.6 1.2 0.9 167.6 0.5 0.1 0.9 0.0 0.1 0.6 0.6 1.0 0.0 0.6 0.0 0.0 0.0 0.1 3.4 0.1 0.2 0.0 0.1 1.7 0.0 0.7 0.1 0.0 0.0 0.4 0.1 0.6 0.0 0.5 0.0 0.4 0.4 0.0 0.4 0.4 0.7 0.3 0.1 0.2 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.3 0.7 0.3 0.0 0.0 0.6 0.0 0.5 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.5 0.2 0.9 0.2 0.8 0.6 0.0 0.7 0.4 0.9 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.1 0.8 0.4 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.6 0.5 0.5 0.3 0.2 0.7 0.6 0.7 0.6 0.5 1.0 0.2 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.3 0.1 1.7 1.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 1462.5 0.5 0.4 2.7 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.8 0.0 0.1 0.7 0.5 0.1 0.0 0.0 0.0 2.0 0.8 0.5 8709.8 47.8 2.2 1.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 57.2 0.1 0.1 0.5 0.2 0.3 0.0 19.7 1.1 0.3 57.7 25.7 0.0 0.1 0.1 0.2 0.0 0.1 0.1 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 TTC22 FLJ20619 ENSG00000006555 "Tetratricopeptide repeat domain 22" Q5TAA0 1 54779712-54801323 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.6;vagina: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 72.4;Gastric mucus-secreting cells: 23.0;Intestinal goblet cells: 27.1;Paneth cells: 36.9;Proximal enterocytes: 51.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A-431: 9.0;CAPAN-2: 10.7;HaCaT: 12.3;hTCEpi: 6.9;OE19: 14.7;RPMI-8226: 8.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035072 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA035072: AB_10602252" "prognostic favorable (2.06e-4)" "unprognostic (8.52e-2)" "unprognostic (4.84e-2)" "unprognostic (4.98e-2)" "unprognostic (1.01e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.02e-1)" "unprognostic (2.60e-1)" "unprognostic (3.07e-2)" "unprognostic (4.57e-2)" "unprognostic (7.27e-2)" "unprognostic (1.51e-3)" "unprognostic (5.08e-3)" "unprognostic (1.00e-1)" "unprognostic (3.16e-2)" "unprognostic (2.21e-1)" 0.4 0.9 1.0 2.4 3.2 1.4 2.6 0.7 1.9 21.7 2.6 14.5 15.7 1.5 2.7 109.6 3.4 2.7 0.2 1.0 2.4 9.3 6.1 2.1 1.6 0.7 0.7 0.4 9.4 16.5 6.1 0.2 0.7 6.3 11.2 0.2 17.5 1.7 0.6 25.0 17.4 0.7 0.5 2.0 13.1 0.7 2.2 2.3 4.1 0.0 7.2 3.7 48.1 0.7 9.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.9 10.7 0.1 0.4 0.0 0.0 12.3 0.0 3.6 0.0 4.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.1 0.1 14.7 1.1 0.1 0.1 8.1 0.5 2.2 0.3 0.2 0.7 0.1 0.0 0.2 0.4 0.2 0.1 0.1 0.0 0.2 0.1 0.8 2.2 0.1 0.1 0.1 0.0 1.0 0.0 2.5 3.4 0.0 2.0 0.7 1.6 3.7 0.0 0.5 1.4 1.7 1.3 1.6 0.0 0.0 2.7 0.5 1.0 3.2 0.7 1.9 1.0 2.4 0.7 0.7 0.7 0.5 2.2 0.7 0.0 0.0 3.1 0.0 1.8 1.3 5.9 3.2 3.4 0.0 3.9 3.6 2.7 15.7 4.5 3.7 0.0 0.3 5.9 72.4 7.9 5.0 2.7 3.3 0.4 0.3 2.4 2.7 0.3 9.1 0.4 0.5 23.0 3.2 0.0 0.0 0.4 2.2 0.0 0.0 0.1 27.1 4.1 0.0 0.3 1.1 0.3 0.4 1.8 0.0 0.0 0.0 7.2 0.0 0.1 10.5 36.9 0.0 1.0 6.0 51.7 8.9 5.7 0.0 0.0 0.0 0.4 0.4 0.9 19.7 4.5 0.0 4.1 0.1 15.4 13.9 TTC38 FLJ20699 ENSG00000075234 "Tetratricopeptide repeat domain 38" Q5R3I4 22 46267961-46294008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 233.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 134.2;NK-cells: 182.3;Proximal enterocytes: 144.5;Proximal tubular cells: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 90.5" "Group enriched" "Detected in all" 4 "granulocytes: 29.9;NK-cells: 38.0;T-cells: 90.5" "Cell line enhanced" "Detected in many" "Hep G2: 76.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029302, HPA075893" Approved Approved Cytosol NA NA 170000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA029302: AB_10601704, HPA075893: " "unprognostic (7.78e-2)" "unprognostic (5.85e-2)" "unprognostic (4.92e-3)" "prognostic favorable (3.21e-6)" "unprognostic (8.34e-2)" "unprognostic (6.38e-2)" "unprognostic (8.72e-2)" "unprognostic (3.62e-2)" "unprognostic (9.45e-2)" "unprognostic (7.22e-2)" "unprognostic (1.12e-1)" "unprognostic (5.66e-2)" "unprognostic (7.34e-3)" "unprognostic (9.02e-2)" "unprognostic (4.12e-1)" "unprognostic (4.97e-1)" "unprognostic (8.33e-2)" 24.7 23.6 9.5 10.2 11.6 46.9 25.7 10.3 10.7 16.8 12.8 42.1 79.4 13.8 6.4 12.5 17.2 15.5 23.2 9.7 11.0 64.4 233.6 15.6 10.7 13.3 12.3 26.0 35.5 7.6 13.2 7.8 11.9 23.6 31.9 4.7 27.0 7.3 20.6 12.2 80.9 10.3 10.3 22.8 29.1 6.8 12.2 2.5 15.2 12.3 5.9 16.9 13.5 11.3 12.0 13.2 16.4 34.5 15.2 13.1 15.7 17.2 11.5 18.7 14.6 21.8 8.5 0.1 10.8 17.9 7.4 10.8 16.8 13.9 6.8 27.0 36.9 15.6 28.4 76.0 21.0 9.0 59.8 22.6 7.3 8.5 9.7 12.9 15.9 0.2 11.9 19.4 12.2 12.1 0.3 28.2 12.5 22.6 13.1 0.0 8.0 8.0 12.6 13.8 2.9 22.8 23.7 16.3 13.3 7.5 26.1 18.0 18.5 13.0 14.1 10.3 11.0 14.7 9.2 1.7 8.8 13.7 13.8 29.9 11.9 22.5 90.5 11.4 9.7 2.3 8.5 41.0 10.8 1.7 3.5 36.9 7.6 38.0 8.7 4.3 4.5 42.5 9.5 11.6 10.3 10.7 9.7 11.0 13.3 12.3 11.9 10.3 12.2 11.3 9.2 0.0 7.5 13.7 6.5 3.3 5.9 4.3 3.4 2.6 10.2 6.7 9.2 38.6 4.3 9.2 6.2 10.4 69.1 69.0 23.5 10.4 0.3 7.4 9.6 8.9 20.9 10.5 0.3 10.2 9.3 7.5 11.7 6.9 17.2 13.3 9.7 134.2 13.4 5.0 1.8 37.8 4.1 14.9 4.3 0.9 7.5 9.6 5.4 9.4 12.8 9.3 182.3 5.5 5.6 9.7 51.6 13.9 16.2 8.6 144.5 149.6 5.3 5.4 6.6 7.4 5.9 1.8 3.7 5.3 8.2 6.4 29.2 22.7 51.7 4.6 TTC39A "C1orf34, DEME-6, KIAA0452" ENSG00000085831 "Tetratricopeptide repeat domain 39A" Q5SRH9 1 51287258-51345116 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 59.5" "Group enriched" "Detected in many" 9 "Early spermatids: 425.0;Late spermatids: 616.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 31.7" "Lineage enriched" "Detected in single" 42 "dendritic cells: 31.7" "Cell line enhanced" "Detected in many" "HDLM-2: 70.6;MCF7: 52.4;SK-BR-3: 153.7;T-47d: 111.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028098, HPA043440" Uncertain Enhanced Centrosome NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" Centrosome "HPA028098: AB_10601705, HPA043440: AB_2678483" "unprognostic (5.05e-2)" "unprognostic (1.95e-1)" "unprognostic (3.35e-2)" "unprognostic (7.60e-2)" "unprognostic (8.53e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (8.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.89e-2)" "unprognostic (1.73e-3)" "unprognostic (5.40e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" 2.2 8.2 3.5 3.3 3.5 1.7 35.9 3.0 9.6 14.1 0.0 29.5 6.1 1.0 15.9 18.4 7.5 14.9 15.3 1.0 11.4 26.6 2.8 9.1 1.4 7.4 5.3 0.3 13.5 13.5 11.0 0.3 14.0 20.5 35.2 4.6 11.5 4.2 4.1 10.5 8.1 1.6 2.2 0.3 29.4 59.5 7.7 0.5 10.1 1.7 2.0 8.0 9.4 3.7 6.4 3.4 0.7 0.3 0.4 0.7 28.2 0.3 0.2 0.2 0.2 18.2 2.8 0.1 9.6 0.4 0.4 0.2 3.8 0.2 0.1 70.6 9.7 0.5 1.8 3.2 1.1 0.0 0.7 0.1 1.6 0.1 0.0 0.8 1.4 0.2 0.4 0.1 0.2 52.4 0.6 0.2 4.8 33.8 0.6 0.1 0.2 4.3 28.6 9.1 22.1 1.6 0.5 153.7 1.8 2.0 111.7 0.8 0.8 0.4 2.5 0.5 0.5 5.4 7.1 0.2 2.1 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 31.7 0.0 0.3 3.5 3.5 3.0 9.6 1.0 11.4 7.4 5.3 14.0 2.2 7.7 3.7 0.4 3.2 25.2 1.3 1.1 1.5 5.3 1.7 0.0 2.5 30.8 15.1 13.0 5.7 6.4 9.2 0.0 0.5 15.3 29.3 11.7 38.9 425.0 5.4 3.0 1.9 41.4 9.7 9.7 52.7 4.8 0.9 21.9 9.5 3.8 0.5 0.4 0.6 2.0 0.0 10.2 56.0 6.1 0.3 1.3 616.8 2.5 0.9 0.0 1.0 2.6 1.7 0.0 0.0 0.9 30.5 13.7 2.6 0.4 12.0 2.7 24.4 9.3 7.3 6.6 1.8 1.3 22.8 6.5 4.8 6.5 3.4 1.7 0.5 20.7 14.6 TTC39C "C18orf17, FLJ33761, HsT2697" ENSG00000168234 "Tetratricopeptide repeat domain 39C" Q8N584 18 23992773-24135610 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 94.2;retina: 143.2" "Cell type enhanced" "Detected in many" "Early spermatids: 149.8;Hepatocytes: 169.3;Late spermatids: 320.0;Rod photoreceptor cells: 241.5" "Cancer enriched" "Detected in all" 4 "liver cancer: 19.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 115.9" "Lineage enriched" "Detected in all" 4 "T-cells: 115.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065705, HPA065713" Approved Approved Nucleoplasm NA NA "Cluster 13: T-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA065705: AB_2685538, HPA065713: AB_2685542" "prognostic favorable (1.48e-4)" "unprognostic (6.37e-2)" "unprognostic (3.66e-1)" "unprognostic (9.97e-2)" "unprognostic (4.37e-2)" "unprognostic (2.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.30e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (2.32e-1)" "unprognostic (3.51e-1)" "unprognostic (8.94e-3)" "unprognostic (4.48e-3)" 21.1 30.5 6.7 12.3 6.4 36.3 18.9 3.2 26.2 20.1 10.8 10.9 9.1 15.6 7.4 16.0 18.6 23.6 7.2 19.9 4.5 6.1 94.2 15.1 19.0 1.6 2.5 10.2 15.8 1.9 20.1 2.7 0.6 20.0 7.4 143.2 25.2 5.4 10.2 56.1 13.4 8.3 2.1 13.2 12.8 33.3 3.6 15.4 7.1 1.6 21.3 13.3 19.6 5.3 12.6 10.4 6.1 3.7 38.3 39.8 22.9 16.4 39.0 13.9 13.5 1.3 6.8 19.7 16.8 30.4 11.1 15.8 12.3 16.5 10.9 28.7 13.1 6.6 50.6 26.3 7.7 31.4 15.3 33.4 21.8 8.4 11.7 26.9 1.1 14.6 0.1 0.2 8.7 10.7 4.9 10.0 14.5 5.5 25.1 28.1 9.5 7.8 14.7 19.7 15.9 12.4 34.5 10.6 11.4 6.5 8.2 10.6 8.3 11.8 9.6 8.7 8.7 0.4 0.1 32.0 16.0 32.9 8.3 2.4 5.4 0.2 32.8 6.1 84.0 16.4 71.7 40.3 7.8 10.0 30.0 25.0 1.5 18.5 5.2 27.8 115.9 13.1 6.7 6.4 3.2 26.2 19.9 4.5 1.6 2.5 0.6 2.1 3.6 5.3 6.9 0.0 3.4 13.7 23.0 46.0 17.1 10.1 30.1 14.7 28.6 24.1 3.0 64.3 5.0 7.3 45.9 0.7 52.0 2.0 0.0 14.2 149.8 72.9 34.9 7.0 4.2 20.6 114.3 11.5 15.2 16.5 15.8 30.0 2.5 11.5 4.6 169.3 12.6 13.5 80.3 9.4 18.3 26.6 44.5 320.0 11.1 21.5 14.2 20.6 18.9 27.8 38.1 41.7 2.3 8.9 1.5 7.9 7.1 20.8 11.4 1.3 16.7 241.5 0.0 5.2 6.7 42.4 8.0 26.8 86.1 0.5 95.9 9.2 9.0 20.1 TTC4 "CNS1, FLJ41930, MGC5097" ENSG00000243725 "Tetratricopeptide repeat domain 4" O95801 1 54715861-54742657 "Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041608, HPA042459" Approved Enhanced "Intermediate filaments,Cytoplasmic bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Intermediate filaments" "Cytoplasmic bodies" "HPA041608: AB_10794485, HPA042459: AB_10797496" "unprognostic (4.89e-2)" "unprognostic (1.81e-1)" "unprognostic (2.05e-2)" "unprognostic (8.62e-4)" "unprognostic (8.91e-2)" "unprognostic (1.34e-1)" "unprognostic (1.21e-5)" "unprognostic (1.39e-4)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (3.18e-1)" "unprognostic (2.42e-3)" "unprognostic (7.12e-2)" "unprognostic (2.85e-1)" "unprognostic (7.79e-2)" "unprognostic (5.86e-2)" "unprognostic (1.76e-3)" 8.9 8.8 21.2 5.3 21.8 2.0 10.4 22.0 24.7 10.4 20.4 9.7 5.6 8.5 8.1 10.6 9.1 3.9 16.5 21.7 22.2 11.0 10.2 5.6 7.2 22.2 22.2 12.5 11.7 11.7 12.8 7.7 22.3 8.8 6.3 9.0 9.1 8.3 33.7 10.3 8.0 7.6 22.5 6.6 10.8 8.6 22.0 12.8 8.0 22.2 8.9 11.0 10.1 23.9 24.3 18.2 20.1 10.9 29.2 16.6 17.9 32.6 16.0 39.8 26.6 20.5 6.9 40.1 17.4 22.4 42.2 13.1 43.7 31.1 41.6 38.2 31.7 38.4 7.7 11.9 27.4 32.4 10.6 16.1 30.4 58.2 34.9 17.8 17.3 31.3 45.5 6.3 22.7 11.3 30.0 18.3 41.0 29.1 30.9 27.1 43.0 22.5 19.9 6.5 13.5 9.7 28.4 13.8 27.2 33.0 13.2 16.5 17.4 19.5 21.2 20.5 44.9 16.1 29.9 34.0 25.9 36.5 20.8 7.3 12.3 10.3 13.9 14.0 14.8 12.6 11.1 13.3 13.5 12.6 15.9 14.3 0.2 18.9 15.1 11.2 11.8 13.0 21.2 21.8 22.0 24.7 21.7 22.2 22.2 22.2 22.3 22.5 22.0 23.9 3.7 9.6 2.6 0.0 6.2 1.1 3.4 2.1 7.4 4.5 3.1 3.3 3.2 1.5 5.2 0.0 0.0 3.9 2.4 1.5 0.0 3.5 0.5 4.7 8.8 3.4 1.2 3.0 0.0 4.2 2.4 5.4 3.6 4.5 7.0 3.0 3.9 2.4 1.4 5.0 0.0 1.3 0.0 0.6 1.5 0.7 4.1 2.7 1.8 0.0 5.9 2.3 6.2 0.0 0.0 3.9 1.7 2.6 6.1 3.0 2.0 6.4 2.6 3.8 0.0 3.8 3.5 9.2 8.2 5.7 1.6 1.4 4.6 1.9 2.5 1.8 TTC6 "C14orf25, NCRNA00291" ENSG00000139865 "Tetratricopeptide repeat domain 6" Q86TZ1 14 37595847-38041442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 7.9;prostate: 17.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 13.8;Club cells: 11.1;Early spermatids: 39.1;Late spermatids: 18.1;Spermatocytes: 10.7" "Group enriched" "Detected in some" 7 "breast cancer: 2.2;prostate cancer: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 8.4;MCF7: 12.2;RT4: 8.4;T-47d: 22.8" "Not detected" "Not detected" "Region enriched" "Detected in some" 7 "midbrain: 9.7" HPA069293 Approved Centrosome NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Centrosome "HPA069293: AB_2686110" "unprognostic (7.92e-2)" "unprognostic (6.95e-2)" "unprognostic (9.22e-2)" "unprognostic (1.98e-1)" "unprognostic (7.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.68e-1)" "unprognostic (3.60e-4)" "unprognostic (6.75e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-4)" "unprognostic (5.60e-2)" "unprognostic (8.91e-8)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-1)" "unprognostic (6.07e-3)" 0.0 0.0 0.5 0.2 0.8 0.0 7.9 0.1 0.8 0.1 1.1 1.0 0.6 0.0 0.0 0.4 0.3 0.7 0.0 0.7 1.0 0.0 3.5 1.1 0.0 2.5 5.0 0.0 0.0 0.0 0.3 0.0 1.3 17.5 0.5 0.0 2.7 0.1 0.0 0.7 0.7 0.0 3.9 0.0 3.6 5.8 3.9 0.0 0.0 0.0 0.1 1.4 0.3 1.0 0.7 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 0.0 0.4 0.0 0.0 2.4 1.3 0.2 0.0 0.0 3.4 0.0 1.2 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 12.2 0.0 0.0 0.0 1.7 4.5 0.0 0.0 0.0 1.0 8.4 2.4 0.0 0.0 4.5 0.0 0.0 22.8 0.0 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.8 0.7 1.0 2.5 5.0 1.3 3.9 3.9 1.0 0.2 0.0 8.4 0.3 0.1 0.0 2.8 1.5 6.2 0.0 13.8 6.9 0.8 1.5 11.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 39.1 0.0 0.0 0.4 7.7 0.0 6.4 0.0 0.0 0.4 7.1 0.1 0.0 0.0 0.0 2.5 0.0 0.0 1.0 0.7 0.0 0.0 0.0 18.1 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.8 0.4 0.0 4.9 0.0 0.0 7.5 0.0 0.0 0.2 0.4 10.7 1.9 2.3 0.0 0.0 0.3 0.0 1.1 3.1 TTK "CT96, MPH1, MPS1, MPS1L1" ENSG00000112742 "TTK protein kinase" P33981 6 80003887-80042527 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 25.3;lymphoid tissue: 46.6;testis: 34.3" "Cell type enhanced" "Detected in many" "Early spermatids: 43.3;Erythroid cells: 23.1;Late spermatids: 21.4;Spermatocytes: 130.5;Spermatogonia: 33.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010166, CAB013229" Enhanced Approved Nucleoli,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Cytosol" "CAB010166: AB_632567, CAB013229: AB_2533230" "unprognostic (4.27e-2)" "unprognostic (8.71e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (1.44e-5)" "unprognostic (7.97e-2)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.84e-10)" "unprognostic (1.56e-3)" "unprognostic (7.95e-2)" "unprognostic (2.02e-3)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.54e-1)" "unprognostic (0.00e+0)" "unprognostic (3.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.46e-1)" "unprognostic (1.66e-1)" 0.7 0.8 0.0 4.2 0.1 25.3 2.2 0.1 0.3 0.7 0.0 4.8 4.0 1.0 0.1 4.8 0.6 0.5 0.1 0.1 0.1 0.2 0.5 0.8 8.1 0.2 0.1 0.2 0.2 0.3 0.0 3.9 0.2 0.8 5.9 1.8 0.7 0.1 0.0 3.6 4.1 1.7 0.1 1.4 3.3 34.3 0.2 46.6 0.4 0.1 9.0 1.2 1.4 0.2 39.9 23.4 68.2 56.4 3.1 9.5 38.5 44.9 27.4 64.2 77.8 32.1 29.6 58.5 34.1 19.5 66.9 50.0 60.7 27.6 88.6 53.4 49.3 54.1 29.4 26.5 0.2 64.4 33.9 1.2 2.8 45.0 28.6 9.6 36.9 80.6 60.2 58.5 55.2 29.5 37.0 46.4 40.4 35.4 27.9 32.7 124.4 24.4 16.3 25.2 46.8 27.4 26.6 28.3 16.3 36.6 26.6 48.3 15.4 28.8 28.5 18.8 72.9 13.1 47.1 32.4 10.3 58.9 25.1 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.2 0.4 0.0 0.7 0.0 0.1 0.0 0.3 0.0 0.0 1.2 0.2 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.3 3.2 1.1 0.0 1.4 1.3 0.6 2.6 0.0 0.2 0.9 0.5 0.6 0.0 2.3 0.0 2.1 9.8 0.8 2.2 3.9 0.4 43.3 3.1 1.6 1.1 1.8 23.1 0.2 0.2 15.0 2.1 2.6 2.3 1.3 13.9 0.7 0.2 6.5 0.0 0.2 3.0 4.1 2.6 1.2 21.4 0.9 1.9 0.0 0.0 5.2 0.2 1.0 0.0 0.1 0.6 0.2 0.7 5.1 0.4 0.3 0.1 3.0 1.6 6.6 0.1 1.7 130.5 33.0 8.5 0.3 3.7 1.1 0.5 5.6 1.6 TTYH1 ENSG00000167614 "Tweety family member 1" Q9H313 19 54415219-54436904 "Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 80.9;choroid plexus: 35.6;testis: 53.4" "Cell type enhanced" "Detected in many" "Astrocytes: 257.6;Bipolar cells: 138.6;Muller glia cells: 653.4;Oligodendrocytes: 97.5;Rod photoreceptor cells: 155.3" "Cancer enriched" "Detected in many" 15 "glioma: 63.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;AN3-CA: 11.7;U-2 OS: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005725, HPA023617, HPA050655" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Plasma membrane" "HPA005725: , HPA023617: AB_10600836, HPA050655: AB_2681204" "prognostic favorable (3.64e-4)" "unprognostic (1.71e-1)" "unprognostic (1.24e-2)" "unprognostic (1.25e-1)" "unprognostic (1.46e-2)" "unprognostic (2.50e-3)" "unprognostic (8.93e-2)" "unprognostic (1.51e-2)" "unprognostic (5.94e-3)" "unprognostic (1.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.60e-1)" "unprognostic (0.00e+0)" "unprognostic (2.09e-1)" "unprognostic (1.41e-1)" "unprognostic (4.45e-2)" "unprognostic (1.69e-1)" 0.9 0.9 64.3 0.0 67.9 0.0 3.5 64.0 80.9 4.0 35.6 10.0 0.2 1.6 0.0 1.1 10.4 0.2 3.6 57.6 59.7 1.2 0.7 0.2 0.0 69.4 66.5 1.5 19.4 0.0 17.7 0.0 63.5 3.5 0.0 3.2 3.6 0.4 3.3 5.9 2.6 0.0 67.6 1.4 2.5 53.4 69.3 0.0 0.3 0.0 0.0 1.7 4.2 66.8 0.1 0.0 7.9 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.2 0.3 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.1 2.9 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.3 67.9 64.0 80.9 57.6 59.7 69.4 66.5 63.5 67.6 69.3 66.8 0.4 3.2 0.6 257.6 0.4 0.8 1.2 0.6 0.0 138.6 44.3 42.2 1.3 4.3 3.0 0.0 20.9 0.9 1.3 0.2 0.0 30.4 3.9 0.3 0.9 2.8 1.2 0.0 26.4 0.6 0.7 1.5 0.0 0.7 0.0 13.7 0.7 0.1 0.3 10.1 3.3 0.0 0.0 0.0 1.5 4.8 1.8 0.3 23.2 19.7 0.3 653.4 0.0 48.2 97.5 2.2 0.0 0.7 0.1 1.9 0.4 0.7 2.8 155.3 6.6 2.3 7.8 2.2 5.1 0.0 0.9 4.2 0.6 0.5 0.3 1.9 TUFT1 ENSG00000143367 "Tuftelin 1" Q9NNX1 1 151540305-151583583 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 111.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.2;Glandular and luminal cells: 76.8;Suprabasal keratinocytes: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 5 "granulocytes: 5.2;T-cells: 3.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 41.7" "HPA028112, HPA054301" Approved Approved Approved Vesicles "Secreted - unknown location" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Vesicles "HPA028112: AB_10603224, HPA054301: AB_2682442" "unprognostic (6.16e-2)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.83e-4)" "unprognostic (4.49e-3)" "unprognostic (1.12e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-2)" "unprognostic (8.29e-3)" "unprognostic (9.06e-2)" "unprognostic (6.70e-3)" "unprognostic (7.88e-2)" "unprognostic (2.58e-3)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (1.82e-3)" "unprognostic (4.53e-2)" 5.6 6.8 4.7 2.8 4.2 6.7 10.1 5.0 5.3 25.4 3.4 11.6 7.5 5.3 6.3 48.1 5.1 5.9 4.9 3.8 5.9 14.1 7.0 8.4 0.9 4.0 4.0 7.4 17.2 11.4 7.2 13.3 5.2 9.6 13.0 2.1 18.3 9.2 2.5 111.5 10.8 6.2 3.3 1.5 12.8 5.4 6.2 2.2 5.7 2.7 6.2 12.4 26.8 3.5 40.7 13.7 10.0 11.5 2.3 1.9 63.1 10.7 9.5 41.3 39.6 43.6 31.5 3.5 64.6 12.5 19.5 46.4 17.6 16.2 30.1 27.0 8.7 2.2 23.0 6.7 32.2 0.8 4.7 6.5 18.9 32.5 71.6 24.5 3.4 5.0 3.6 26.8 12.8 16.8 2.0 0.5 11.7 29.6 11.4 0.1 28.1 14.2 34.7 61.8 19.5 8.0 68.2 45.8 8.0 29.4 36.5 2.1 8.6 7.4 51.7 46.2 71.7 6.6 13.7 0.5 6.3 0.9 4.7 5.2 0.6 0.7 0.3 0.1 0.7 0.6 1.0 0.5 0.9 0.2 0.8 0.3 2.5 0.1 0.3 0.1 3.5 0.5 4.7 4.2 5.0 5.3 3.8 5.9 4.0 4.0 5.2 3.3 6.2 3.5 2.1 25.6 2.0 1.6 3.8 69.2 35.2 14.7 35.9 2.5 28.8 20.2 9.8 8.6 19.0 14.7 0.0 28.1 6.6 59.5 13.7 18.2 2.7 43.2 8.9 2.7 32.2 2.7 4.4 15.2 13.9 7.0 46.9 76.8 4.5 9.0 1.1 10.5 4.0 0.0 9.3 39.1 20.3 0.0 12.7 3.2 2.5 6.5 8.8 1.0 2.0 2.1 0.0 8.5 1.8 47.4 34.6 5.3 7.7 21.7 15.4 11.2 15.9 0.5 6.6 4.1 5.5 0.6 3.5 39.6 66.5 56.8 5.8 10.9 35.7 35.6 TULP1 "LCA15, RP14, TUBL1" ENSG00000112041 "TUB like protein 1" O00294 6 35497874-35512896 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Sensory transduction, Vision" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 286 "retina: 209.1" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 266.9;Rod photoreceptor cells: 393.2" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;MCF7: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 28: BEWO - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (7.98e-2)" "unprognostic (2.33e-2)" "unprognostic (4.38e-2)" "unprognostic (4.60e-5)" "unprognostic (2.28e-2)" "unprognostic (3.12e-3)" "unprognostic (3.30e-1)" "unprognostic (5.49e-3)" "unprognostic (1.85e-1)" "unprognostic (2.66e-2)" "unprognostic (7.42e-2)" "unprognostic (1.66e-6)" "unprognostic (1.72e-1)" "unprognostic (1.30e-1)" "unprognostic (5.42e-2)" "unprognostic (4.11e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.4 0.3 0.1 0.0 0.3 0.4 0.2 0.5 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.7 0.0 209.1 0.2 0.3 0.0 0.5 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 64.2 0.0 0.0 0.7 0.0 0.0 0.0 266.9 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.3 2.6 0.0 0.0 0.1 0.0 2.4 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 18.5 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 55.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 393.2 0.0 0.4 0.2 0.1 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.4 TULP4 "KIAA1397, TUSP" ENSG00000130338 "TUB like protein 4" Q9NRJ4 6 158232236-158511828 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 32.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 171.0;Oligodendrocytes: 544.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005445 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA005445: AB_1080421" "unprognostic (6.51e-3)" "unprognostic (1.83e-1)" "unprognostic (2.05e-1)" "unprognostic (1.39e-1)" "unprognostic (3.41e-1)" "unprognostic (9.77e-2)" "unprognostic (6.07e-2)" "unprognostic (1.55e-1)" "unprognostic (2.32e-1)" "unprognostic (4.79e-2)" "unprognostic (1.42e-2)" "unprognostic (3.04e-1)" "unprognostic (2.01e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-1)" "unprognostic (9.65e-2)" 2.4 2.5 27.1 2.1 32.7 1.1 3.1 15.0 16.1 2.8 0.0 2.5 4.0 3.0 2.8 3.5 2.1 2.2 2.6 15.2 13.1 3.1 2.3 2.7 3.1 16.1 23.9 2.5 2.7 5.0 4.6 2.6 10.8 2.4 2.0 7.0 3.1 2.4 6.3 6.0 4.3 2.4 14.8 2.9 3.0 4.0 19.3 3.2 4.6 3.6 3.0 2.4 3.0 27.1 2.7 5.7 4.1 9.1 7.2 4.5 8.6 2.6 3.7 2.4 2.9 8.4 1.7 7.4 2.5 5.3 7.0 4.7 4.9 6.4 4.4 4.8 2.7 3.7 4.2 8.7 5.2 3.4 3.9 3.5 7.3 4.0 8.3 8.7 6.2 7.0 5.8 11.3 6.8 4.1 3.5 3.9 2.8 3.2 2.6 7.4 9.8 4.7 4.0 4.3 7.9 9.8 7.5 11.1 8.0 3.9 6.5 4.5 10.0 6.2 7.4 9.2 10.1 7.7 10.1 6.2 5.9 2.6 7.8 0.3 1.4 0.0 1.8 1.5 2.4 1.8 2.1 2.4 0.9 1.9 1.5 1.7 0.1 1.3 2.1 3.2 2.9 1.6 27.1 32.7 15.0 16.1 15.2 13.1 16.1 23.9 10.8 14.8 19.3 27.1 27.0 3.2 25.4 62.7 25.8 21.4 16.4 12.3 16.5 51.2 31.3 22.5 52.8 12.8 20.6 25.8 171.0 29.4 25.9 16.5 15.6 18.0 5.3 46.5 51.2 25.7 20.4 7.8 157.3 15.7 8.9 20.0 13.7 51.6 5.1 17.7 16.8 15.2 12.9 158.2 153.4 13.3 8.2 17.9 10.7 8.4 28.3 15.4 16.0 76.8 13.0 16.1 14.4 137.2 544.9 22.5 15.3 41.8 24.7 20.8 53.2 26.0 18.8 79.8 13.1 33.9 26.8 21.8 33.5 19.6 39.2 18.9 21.1 52.4 17.3 23.6 TUT7 "FLJ13409, KIAA1711, PAPD6, TENT3B, ZCCHC6" ENSG00000083223 "Terminal uridylyl transferase 7" Q5VYS8 9 86287733-86354454 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 80.3;Endometrial stromal cells: 61.1;Glandular and luminal cells: 206.7;Syncytiotrophoblasts: 92.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 114.6" "Group enriched" "Detected in all" 5 "granulocytes: 114.6;monocytes: 47.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020615, HPA020620" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Cytosol Nucleoplasm "HPA020615: AB_1858983, HPA020620: AB_1858984" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.64e-1)" "unprognostic (1.26e-2)" "unprognostic (3.66e-1)" "unprognostic (1.39e-1)" "unprognostic (4.11e-2)" "unprognostic (2.49e-2)" "unprognostic (4.43e-2)" "unprognostic (6.51e-2)" "unprognostic (1.91e-2)" "unprognostic (3.07e-1)" "unprognostic (5.79e-3)" "unprognostic (1.59e-2)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (1.40e-1)" 12.5 9.4 4.8 16.0 6.4 22.6 18.7 5.9 10.0 12.8 10.9 12.1 11.0 9.1 8.9 24.7 8.8 11.3 8.2 5.1 7.9 7.5 38.4 16.5 19.1 9.0 6.3 8.7 13.1 8.7 8.2 14.3 7.8 20.8 11.8 7.7 14.2 7.2 13.6 33.7 12.3 7.8 5.1 20.6 13.6 11.6 9.2 15.1 8.6 9.3 19.2 13.4 16.0 9.0 16.2 17.2 9.8 14.3 22.4 36.0 12.2 21.6 20.5 9.1 10.6 7.8 13.7 22.8 18.9 14.0 9.5 27.3 11.8 12.0 13.5 27.1 6.0 16.5 18.4 13.7 19.3 19.1 21.8 23.5 22.7 14.5 16.2 13.7 15.0 12.3 15.9 24.0 24.6 14.9 16.0 11.0 7.5 25.1 11.1 8.0 17.5 10.1 15.3 31.4 7.2 5.7 13.1 15.5 7.4 11.6 6.4 7.8 24.8 8.7 10.5 15.7 14.8 27.4 23.3 16.5 20.7 10.8 11.8 35.4 19.4 20.5 15.0 24.7 12.5 11.6 8.2 10.7 11.9 12.2 9.5 10.1 114.6 12.8 47.8 5.5 8.8 8.9 4.8 6.4 5.9 10.0 5.1 7.9 9.0 6.3 7.8 5.1 9.2 9.0 28.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 34.2 16.4 0.0 0.0 0.0 9.2 0.0 22.4 36.6 0.0 5.9 29.6 0.0 80.3 61.1 7.2 0.0 0.0 0.0 17.9 17.4 5.6 0.0 206.7 0.0 36.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.0 12.4 0.0 0.0 0.0 0.0 27.8 0.0 0.0 13.8 0.0 0.0 6.7 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 92.5 14.8 30.9 0.0 0.0 TYMS "HsT422, TMS, TS, Tsase" ENSG00000176890 "Thymidylate synthetase" P04818 18 657653-673578 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.5;lymphoid tissue: 113.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 105.8;Erythroid cells: 189.3;Extravillous trophoblasts: 115.3;Plasma cells: 112.7;Spermatocytes: 180.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.1" "Group enriched" "Detected in many" 6 "NK-cells: 6.7;T-cells: 14.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002784, HPA074922" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB002784: , HPA074922: " "unprognostic (7.58e-2)" "unprognostic (2.06e-3)" "unprognostic (9.31e-2)" "unprognostic (2.34e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.10e-6)" "unprognostic (1.62e-3)" "unprognostic (1.68e-2)" "unprognostic (9.82e-2)" "unprognostic (1.07e-3)" "unprognostic (3.28e-2)" "unprognostic (1.23e-2)" "unprognostic (6.34e-2)" "unprognostic (1.66e-1)" "unprognostic (5.65e-3)" "unprognostic (2.47e-1)" 4.5 3.1 4.3 24.2 7.5 88.5 6.7 4.1 6.5 4.8 2.7 22.9 10.5 5.1 1.3 14.8 5.6 3.8 2.2 5.0 4.9 6.5 11.8 4.9 36.1 4.9 5.2 2.1 3.6 1.8 1.6 22.3 4.4 3.1 27.1 4.2 3.9 2.0 0.4 6.2 14.8 12.7 4.8 10.6 8.8 34.3 6.1 113.6 2.1 0.4 44.5 8.4 5.5 10.3 102.7 156.6 320.4 154.9 35.1 57.9 159.9 238.9 141.1 251.7 299.9 132.8 80.1 160.0 91.5 129.9 143.2 45.1 225.3 89.7 216.1 152.3 244.9 273.1 135.8 229.4 8.2 564.8 286.5 51.5 20.7 159.6 49.6 48.4 214.4 334.0 222.0 249.6 321.8 118.1 687.7 311.4 114.7 124.3 114.0 446.8 287.0 191.3 95.6 88.9 106.0 175.7 201.4 91.6 61.1 197.3 63.5 253.5 85.0 289.7 569.5 267.3 474.2 305.9 405.2 367.3 75.2 240.6 339.2 0.0 0.0 1.3 1.1 0.1 0.0 1.1 2.8 2.2 1.8 0.0 0.0 0.6 0.7 6.7 0.1 0.3 14.1 2.9 4.3 7.5 4.1 6.5 5.0 4.9 4.9 5.2 4.4 4.8 6.1 10.3 2.1 0.0 2.3 1.6 15.7 14.4 15.9 13.0 27.9 0.5 7.8 11.7 3.6 2.8 6.7 0.0 0.0 105.8 14.5 15.5 1.9 2.3 34.4 5.6 8.4 12.5 1.2 189.3 0.4 0.8 115.3 28.3 14.3 7.4 7.0 76.2 6.8 4.3 71.4 0.0 0.6 20.9 10.2 15.6 19.4 31.9 6.2 10.7 10.6 1.0 3.9 45.0 5.2 0.5 15.6 1.5 8.9 3.8 112.7 5.0 13.8 36.6 1.0 2.4 13.1 1.3 32.6 180.8 30.7 48.0 7.2 27.0 21.3 10.5 54.9 18.7 TYR "OCA1, OCA1A, OCAIA" ENSG00000077498 Tyrosinase P14679 11 89177875-89295759 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase, Tumor antigen" "Albinism, Deafness, Disease variant, FDA approved drug targets, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "skin 1: 31.6" "Cell type enriched" "Detected in some" 5 "Melanocytes: 184.9" "Cancer enriched" "Detected in single" 1755 "melanoma: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 995 "SK-MEL-30: 426.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000079, HPA043241, HPA050889, HPA064583" Enhanced Enhanced Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "CAB000079: AB_564045, HPA043241: AB_2678383, HPA050889: AB_2681264, HPA064583: " "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-3)" "unprognostic (9.75e-3)" 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 426.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.9 0.3 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.5 5.2 0.3 0.0 184.9 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.0 0.0 0.1 0.0 0.0 0.0 TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583589 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.0;ovary: 49.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.4;Leydig cells: 44.4;Oligodendrocyte precursor cells: 29.1;Oligodendrocytes: 46.8;Peritubular cells: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Cell line enhanced" "Detected in many" "BEWO: 69.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved NA NA 17000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071245: AB_2686371" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" 21.5 3.5 18.2 1.4 30.3 0.8 5.2 17.7 27.1 2.1 0.0 2.3 1.6 4.6 3.5 13.1 11.5 2.5 2.2 27.7 10.7 11.3 0.8 3.3 1.3 20.9 22.6 49.7 9.8 0.9 0.9 5.7 18.6 2.6 0.9 2.6 1.9 6.1 0.9 13.8 2.4 4.4 14.4 5.5 3.2 18.8 15.7 0.4 1.1 1.8 3.7 2.1 4.1 32.0 10.3 6.7 20.7 22.7 18.9 12.8 69.2 14.6 9.3 14.2 13.1 37.7 3.4 0.4 18.3 11.9 19.9 23.7 23.3 3.6 6.5 5.8 15.5 3.2 20.2 18.1 13.3 5.2 0.4 4.1 7.3 10.9 3.6 5.8 10.6 9.8 19.1 4.3 7.9 9.8 2.4 1.0 47.7 16.0 6.7 31.9 18.6 3.8 1.2 19.7 24.6 7.0 13.7 21.6 16.3 29.8 17.8 6.0 8.4 28.0 12.2 21.0 22.5 1.7 3.5 3.1 17.2 33.8 17.2 1.1 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.3 0.2 0.2 1.5 0.3 0.1 0.3 0.1 0.1 18.2 30.3 17.7 27.1 27.7 10.7 20.9 22.6 18.6 14.4 15.7 32.0 3.4 3.2 1.1 17.6 0.9 6.8 8.5 0.4 0.6 2.7 2.2 2.2 2.9 2.8 0.7 3.7 6.2 2.9 1.1 1.3 0.0 3.9 3.6 1.1 13.0 5.4 1.8 0.0 42.4 3.6 10.2 10.5 8.6 1.9 0.0 7.6 9.7 0.4 1.2 0.0 4.6 0.9 0.0 1.9 1.3 5.1 44.4 0.9 8.8 1.0 0.1 8.3 1.0 29.1 46.8 4.6 0.1 47.0 0.3 6.4 1.2 1.2 0.5 4.0 0.0 3.9 4.3 4.0 6.5 4.2 10.9 18.9 0.7 5.8 2.3 5.7 TYRP1 "b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP" ENSG00000107165 "Tyrosinase related protein 1" P17643 9 12685439-12710285 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 44.8;heart muscle: 59.9;skin 1: 145.0" "Cell type enriched" "Detected in some" 17 "Melanocytes: 2486.6" "Cancer enriched" "Detected in some" 262 "melanoma: 313.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "SK-MEL-30: 1395.0" "Group enriched" "Detected in some" 5 "olfactory bulb: 4.6;thalamus: 1.8" "Low region specificity" "Detected in all" "HPA000937, CAB002520" Enhanced Approved Vesicles NA NA 51000 "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB002520: AB_564153, HPA000937: AB_1080437" "unprognostic (7.48e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-1)" "unprognostic (3.16e-3)" "unprognostic (8.10e-2)" "unprognostic (3.82e-3)" "unprognostic (1.53e-1)" "unprognostic (2.25e-3)" "unprognostic (4.46e-1)" "unprognostic (8.71e-2)" "unprognostic (6.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-6)" "unprognostic (1.27e-1)" "unprognostic (5.99e-2)" "unprognostic (1.95e-2)" 0.3 0.0 0.1 0.6 0.4 0.2 4.9 0.3 0.9 0.0 44.8 2.2 5.0 0.0 1.2 10.0 0.2 4.5 59.9 2.6 0.0 16.2 0.0 3.7 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 5.3 2.7 1.3 0.0 4.8 145.0 4.7 1.8 0.1 0.0 2.1 1.1 0.3 0.0 0.0 7.5 0.0 1.1 0.4 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 25.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 4.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 1395.0 0.1 19.5 1.5 0.0 0.0 0.7 0.0 0.9 0.0 0.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.9 2.6 0.0 1.2 1.1 2.1 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 92.3 0.1 0.0 0.0 11.7 0.0 0.0 44.3 0.0 0.0 3.7 2.1 0.0 0.0 0.0 144.8 0.3 2.5 0.0 0.0 1.3 0.0 0.0 0.9 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 17.5 4.7 0.3 0.0 2486.6 0.0 0.0 15.9 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.6 0.0 0.0 1.4 0.7 0.7 0.0 16.8 0.0 0.5 0.0 0.0 0.2 TYSND1 "MGC34695, NET41" ENSG00000156521 "Trypsin like peroxisomal matrix peptidase 1" Q2T9J0 10 70137981-70146700 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 120.7;Late spermatids: 227.4;Spermatocytes: 124.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 27.5;PC-3: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030304 Approved Uncertain Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" Cytosol "HPA030304: AB_10670560" "unprognostic (4.75e-3)" "unprognostic (4.30e-2)" "unprognostic (2.44e-2)" "unprognostic (7.69e-2)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.02e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (1.10e-1)" "unprognostic (1.59e-2)" "unprognostic (2.80e-1)" "unprognostic (1.37e-1)" "unprognostic (9.26e-3)" "unprognostic (1.91e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" 5.7 6.0 1.4 1.9 1.3 0.9 5.4 1.7 1.8 5.8 1.1 4.9 3.3 4.1 0.6 11.8 4.5 0.6 2.9 1.0 0.9 5.2 6.4 2.8 1.8 2.1 0.7 4.2 6.2 1.3 3.4 1.3 0.8 5.7 0.6 0.2 5.7 1.5 3.2 11.4 5.0 0.3 0.6 5.4 3.9 14.2 0.9 1.2 4.6 0.5 0.9 4.8 6.5 1.4 16.0 10.2 0.8 6.2 1.0 0.9 3.7 2.2 1.4 2.0 1.8 6.2 9.6 13.8 6.0 0.5 0.6 27.5 1.0 3.9 0.4 8.9 9.5 0.7 2.9 3.3 2.4 1.2 0.1 2.0 7.6 1.7 3.1 1.2 1.4 4.9 0.1 4.3 0.8 6.3 5.3 5.6 3.3 3.5 41.7 8.9 2.6 6.2 0.9 2.6 7.4 3.8 6.7 14.8 6.1 0.2 9.4 1.1 2.6 2.5 1.7 4.8 8.7 14.9 9.9 7.0 2.9 6.2 1.8 0.0 0.8 0.7 3.8 1.2 2.4 3.0 2.2 2.8 0.9 3.3 3.0 2.6 0.3 2.0 0.7 0.7 2.6 1.4 1.4 1.3 1.7 1.8 1.0 0.9 2.1 0.7 0.8 0.6 0.9 1.4 6.1 9.6 5.3 4.9 12.6 14.3 14.5 13.3 14.8 6.9 14.8 16.9 4.2 27.1 7.8 11.0 0.0 35.2 15.5 14.6 17.6 7.8 120.7 5.5 6.8 6.3 14.3 5.0 6.7 9.5 9.8 7.5 5.1 6.3 13.4 9.3 6.8 16.5 12.1 0.0 6.0 12.1 16.2 10.7 6.6 227.4 9.3 8.2 12.4 6.5 6.1 7.0 12.3 11.6 5.5 5.5 11.6 7.9 7.5 14.5 19.2 16.5 3.9 4.4 6.6 6.9 6.1 124.7 12.5 22.4 18.5 16.7 14.0 10.6 21.0 8.8 UBAC1 "GBDR1, KPC2, UBADC1" ENSG00000130560 "UBA domain containing 1" Q9BSL1 9 135932969-135961373 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 301.3;tongue: 171.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 290.9;Late spermatids: 197.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 246.4;K-562: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005651 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 87000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA005651: AB_1858489" "unprognostic (8.41e-2)" "prognostic favorable (4.34e-6)" "unprognostic (2.10e-1)" "unprognostic (9.15e-2)" "unprognostic (4.11e-1)" "unprognostic (3.85e-2)" "unprognostic (7.68e-3)" "unprognostic (2.85e-1)" "unprognostic (4.37e-2)" "unprognostic (3.23e-1)" "unprognostic (3.92e-3)" "unprognostic (1.20e-1)" "prognostic favorable (3.58e-7)" "unprognostic (1.95e-3)" "unprognostic (9.46e-2)" "unprognostic (3.16e-2)" "unprognostic (5.78e-2)" 23.1 20.7 42.2 14.7 44.8 82.5 20.7 43.0 43.0 23.8 41.4 38.6 24.3 22.0 12.9 37.4 22.8 12.0 72.0 40.4 42.2 23.5 24.9 19.8 15.7 43.2 42.7 20.9 17.1 27.1 23.5 22.8 41.8 24.7 18.4 15.2 27.8 20.6 301.3 53.2 23.3 16.3 43.7 21.0 23.0 43.1 44.0 17.7 18.0 171.0 16.5 28.3 27.0 41.0 37.4 42.7 29.7 43.4 22.0 25.6 55.7 32.0 27.1 38.9 31.2 59.7 46.3 44.8 30.1 26.4 46.1 124.4 41.9 37.0 17.5 246.4 39.6 37.4 79.0 33.8 22.9 49.2 34.4 24.2 47.7 24.6 23.8 26.0 32.8 41.4 316.6 35.5 31.2 76.9 40.4 50.5 70.5 87.4 71.8 45.1 55.8 59.3 28.0 23.7 46.0 50.6 46.3 41.4 33.5 26.3 34.9 52.5 26.8 22.0 33.0 26.5 40.2 20.5 41.1 53.9 40.7 43.9 30.6 6.5 17.6 8.7 4.8 28.4 5.1 4.9 5.4 3.2 15.6 2.8 2.8 3.3 3.7 4.0 33.4 1.6 4.5 7.0 42.2 44.8 43.0 43.0 40.4 42.2 43.2 42.7 41.8 43.7 44.0 41.0 42.8 16.0 10.0 18.6 14.5 40.7 38.8 41.8 43.3 38.3 29.6 36.2 85.7 11.5 24.5 27.6 31.3 148.6 20.7 45.5 93.9 16.3 101.6 82.9 33.7 27.5 16.8 290.9 17.3 22.9 32.7 22.5 21.9 21.3 7.0 28.6 20.3 32.7 75.2 13.5 23.6 37.4 28.5 34.3 30.3 197.4 19.6 41.8 35.6 9.4 46.0 60.7 13.4 9.0 14.1 22.6 42.3 22.6 24.6 23.1 47.9 35.6 96.0 44.1 19.7 42.8 27.4 57.7 54.9 73.2 64.8 60.5 16.5 25.7 55.6 39.4 UBAP2 "bA176F3.5, FLJ22435, KIAA1491" ENSG00000137073 "Ubiquitin associated protein 2" Q5T6F2 9 33921693-34048949 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021684 Approved Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA021684: AB_2211887" "unprognostic (2.71e-1)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (1.21e-1)" "unprognostic (4.64e-2)" "prognostic favorable (8.59e-4)" "unprognostic (1.75e-1)" "unprognostic (9.76e-3)" "prognostic favorable (1.95e-4)" "unprognostic (8.06e-2)" "unprognostic (2.39e-1)" "unprognostic (2.95e-1)" "unprognostic (8.77e-2)" 12.2 25.7 12.5 8.2 12.9 17.2 12.8 17.3 13.4 15.5 5.3 13.8 8.7 13.0 8.8 19.1 11.4 6.6 15.3 9.5 13.7 14.9 11.1 13.2 10.4 9.4 9.5 15.2 15.4 9.3 11.0 11.8 9.7 14.3 12.1 9.9 13.1 6.7 37.8 22.2 10.8 10.3 6.8 10.9 14.0 32.5 13.6 13.9 15.8 20.5 12.1 12.5 15.2 12.9 40.5 36.5 25.9 32.9 25.2 22.0 31.2 31.8 19.6 32.1 31.0 49.9 21.0 46.8 9.8 26.7 24.7 23.1 43.9 34.9 35.5 34.8 21.5 26.2 47.2 55.0 20.5 59.6 40.3 20.4 28.8 40.8 28.2 16.7 26.3 28.3 36.5 37.6 29.4 26.9 44.6 100.4 27.7 22.6 28.5 34.1 16.0 29.9 31.2 30.1 26.5 18.4 37.6 30.3 9.4 25.8 26.9 26.3 30.9 19.0 25.5 22.8 35.7 14.5 32.3 49.3 20.9 22.5 48.3 1.6 2.7 3.0 2.2 3.1 4.7 2.7 2.7 3.2 3.1 1.4 2.4 3.3 1.6 4.5 7.2 4.1 3.3 2.3 12.5 12.9 17.3 13.4 9.5 13.7 9.4 9.5 9.7 6.8 13.6 12.9 23.8 54.5 23.1 56.8 15.0 28.2 23.8 21.0 27.3 28.7 25.3 26.2 59.9 8.6 32.4 12.9 60.5 44.4 24.7 28.1 3.9 20.0 102.8 52.5 30.3 28.6 25.1 20.8 46.8 19.8 36.3 23.7 32.6 68.8 14.5 36.2 11.7 14.0 16.6 16.8 48.3 30.4 14.2 17.0 21.4 85.0 30.4 17.1 26.6 33.7 19.0 12.5 16.5 50.8 46.3 27.0 26.8 24.5 28.4 24.9 12.3 15.9 24.1 27.0 26.3 27.4 22.6 81.0 70.4 25.9 31.1 72.9 22.3 68.4 29.6 23.7 UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655722-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.0;lymphoid tissue: 15.6;placenta: 13.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.9;Inhibitory neurons: 166.3;Langerhans cells: 51.2;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 122.2;HMC-1: 88.9;hTEC/SVTERT24-B: 72.9;REH: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038605, HPA038606, HPA038607" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 23000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Nuclear bodies" "HPA038605: AB_10669648, HPA038606: , HPA038607: AB_2676112" "unprognostic (4.94e-2)" "unprognostic (6.03e-3)" "unprognostic (1.34e-1)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.09e-2)" "unprognostic (4.67e-3)" "unprognostic (1.21e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (6.20e-2)" "unprognostic (9.02e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (2.72e-3)" "unprognostic (1.53e-1)" 3.4 0.7 1.1 4.8 1.5 6.7 1.1 15.0 1.9 3.0 0.1 1.2 1.3 1.0 0.2 1.1 0.5 1.9 0.9 1.2 5.5 1.7 1.3 4.6 5.7 10.3 7.1 0.2 0.6 0.4 0.3 13.8 10.2 0.7 1.4 1.9 0.7 0.7 1.1 3.4 1.7 1.9 1.2 15.6 1.4 1.2 2.8 15.1 2.3 0.3 3.2 4.4 0.5 1.4 13.1 31.5 5.6 7.5 2.4 4.4 29.1 45.6 25.1 18.1 13.9 12.5 6.8 5.3 3.5 24.3 17.2 6.4 0.1 16.3 28.7 0.2 0.9 122.2 1.0 10.8 6.7 15.0 88.9 3.9 1.0 72.9 26.9 19.7 12.4 5.3 0.1 0.1 17.8 0.5 18.5 9.6 2.5 13.3 7.4 73.3 3.3 0.7 28.6 10.9 12.7 0.2 12.1 0.9 10.1 11.7 0.2 4.0 32.3 23.4 12.6 13.9 19.1 1.0 0.0 15.1 12.4 20.6 43.4 0.0 1.3 9.9 1.8 6.3 1.9 0.3 2.3 1.7 1.7 1.1 2.6 1.4 2.7 6.4 11.1 0.2 4.7 1.8 1.1 1.5 15.0 1.9 1.2 5.5 10.3 7.1 10.2 1.2 2.8 1.4 2.2 0.0 4.7 9.1 4.6 7.1 4.2 3.4 2.8 1.8 1.2 1.3 1.1 0.0 2.0 3.7 0.0 32.5 10.0 0.6 0.0 8.4 2.4 0.6 4.0 4.5 0.0 1.7 24.8 9.7 54.9 4.9 2.0 1.5 12.7 11.5 5.0 0.6 35.7 11.8 166.3 0.5 4.1 26.0 51.2 3.9 0.0 26.5 1.8 30.0 9.1 0.2 17.5 26.2 2.7 26.3 0.3 0.4 11.4 4.7 0.2 0.6 2.5 1.1 0.0 3.8 3.4 0.1 0.8 2.4 6.0 47.6 16.8 0.1 0.4 3.1 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UBE2G1 "UBC7, UBE2G" ENSG00000132388 "Ubiquitin conjugating enzyme E2 G1" P62253 17 4269259-4366628 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 210.2" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 286.0;Late spermatids: 248.3;Suprabasal keratinocytes: 239.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045681, HPA050551" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Cytosol" "HPA045681: AB_2679417, HPA050551: AB_2681171" "unprognostic (1.57e-3)" "unprognostic (1.94e-1)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (5.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.80e-1)" "unprognostic (1.67e-2)" "unprognostic (9.99e-2)" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" "unprognostic (3.97e-2)" "unprognostic (6.50e-2)" 21.0 19.1 15.8 25.4 21.4 31.5 20.1 21.0 24.3 25.2 11.6 39.7 22.5 22.7 14.7 52.2 16.3 16.0 37.9 16.1 18.7 27.0 30.3 15.6 38.8 21.5 19.2 15.6 18.4 21.5 9.7 18.9 21.7 22.6 24.2 17.5 21.0 20.8 210.2 28.0 23.6 27.2 20.3 20.7 21.8 23.2 21.0 24.9 16.1 84.1 46.4 24.5 32.1 26.5 54.5 57.8 52.7 38.9 42.2 44.3 74.9 51.7 41.4 48.2 42.1 40.0 27.0 84.5 52.8 51.2 39.4 57.2 66.3 48.1 77.2 44.8 53.9 31.7 28.6 45.9 41.3 46.5 57.4 38.0 70.3 45.8 66.1 33.8 65.6 55.8 56.5 88.9 40.1 24.3 59.4 42.5 58.2 40.1 29.6 76.1 27.9 78.1 56.4 35.1 22.7 42.3 48.9 41.8 41.6 77.4 41.1 29.9 49.6 48.1 36.8 57.0 58.7 34.3 43.8 118.9 36.9 42.8 37.7 13.3 15.8 39.0 22.2 16.8 29.9 34.1 28.3 29.1 20.2 24.4 28.3 28.9 28.1 32.5 18.6 14.8 28.9 21.8 15.8 21.4 21.0 24.3 16.1 18.7 21.5 19.2 21.7 20.3 21.0 26.5 28.3 22.4 14.4 31.3 70.6 286.0 36.5 47.8 111.5 18.8 47.0 31.0 67.6 27.1 32.2 25.8 6.2 47.0 47.8 41.4 82.2 30.9 139.5 36.7 25.7 35.5 38.4 26.5 47.9 26.7 59.6 31.1 32.6 39.9 21.0 13.9 31.1 62.3 48.1 15.2 46.3 38.3 44.7 36.5 81.1 248.3 19.6 35.7 67.6 30.9 43.1 28.7 36.0 36.2 84.4 43.0 30.4 21.1 154.3 65.7 40.4 75.6 35.4 17.1 6.6 25.9 43.5 70.8 50.8 85.3 239.7 66.8 58.2 13.8 30.1 54.0 UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448859-6496723 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 26.1;heart muscle: 16.8;retina: 28.3;skeletal muscle: 54.5;tongue: 13.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.0;Cardiomyocytes: 27.6;Excitatory neurons: 47.8;Granulosa cells: 45.5;Horizontal cells: 45.4;Inhibitory neurons: 35.3;Rod photoreceptor cells: 63.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 29.7;PC-3: 24.6;SCLC-21H: 23.1;U-266/70: 54.4;U-266/84: 52.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favorable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" 1.2 1.4 14.3 0.4 14.6 0.0 1.1 16.5 26.1 2.1 1.8 5.3 0.3 0.8 1.0 0.4 0.7 0.4 16.8 17.9 11.4 3.4 1.2 0.1 0.1 12.0 7.9 2.6 0.6 0.1 3.2 0.0 11.6 3.5 0.3 28.3 0.8 5.5 54.5 1.5 1.4 0.7 5.6 0.2 2.9 0.7 10.1 0.3 1.2 13.9 0.2 0.3 1.3 17.7 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.7 0.0 5.3 0.0 0.0 0.3 0.0 24.6 0.1 0.0 11.5 0.0 0.0 23.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 54.4 52.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 14.6 16.5 26.1 17.9 11.4 12.0 7.9 11.6 5.6 10.1 17.7 0.2 0.0 0.0 5.5 0.3 1.3 0.5 0.5 0.0 30.0 0.4 1.0 27.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 5.9 0.0 0.0 0.2 0.4 1.0 5.4 0.0 47.8 0.2 0.0 3.6 1.1 0.1 0.0 45.5 0.0 1.0 0.1 45.4 35.3 0.0 0.0 0.3 0.3 0.3 4.1 0.1 0.0 2.8 0.0 9.4 0.0 12.1 5.4 0.1 0.0 6.8 1.8 0.9 0.0 0.2 0.0 63.6 0.0 3.2 1.4 0.1 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.0 UBE2T "FANCT, HSPC150" ENSG00000077152 "Ubiquitin conjugating enzyme E2 T" Q9NPD8 1 202331657-202341980 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.5;Erythroid cells: 134.3;Extravillous trophoblasts: 103.4;Spermatocytes: 114.1;Spermatogonia: 113.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002831 Approved Nucleoplasm,Nucleoli NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoli Nucleoplasm "HPA002831: AB_1080445" "unprognostic (2.38e-3)" "unprognostic (6.37e-2)" "unprognostic (5.27e-2)" "unprognostic (5.19e-2)" "unprognostic (2.81e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.71e-2)" "unprognostic (2.32e-2)" "prognostic favorable (6.90e-6)" "unprognostic (6.28e-3)" "unprognostic (2.85e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (5.37e-3)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" 2.3 3.7 6.6 10.4 6.5 28.7 4.5 5.8 13.7 4.1 5.0 13.1 8.7 4.5 4.4 10.6 3.3 2.5 11.3 6.8 7.4 3.5 3.2 3.0 19.0 6.5 6.6 1.0 0.7 4.4 3.0 10.1 6.9 2.1 15.5 2.5 2.7 3.1 17.2 5.3 8.2 9.4 6.0 6.2 4.7 19.3 6.7 47.1 2.9 13.0 18.6 6.3 5.0 6.1 123.3 111.6 167.1 79.8 15.4 27.9 94.2 130.2 72.8 146.0 102.6 79.9 147.1 140.4 50.0 47.0 108.4 98.6 154.1 76.7 131.2 128.1 87.2 85.6 54.0 93.8 6.9 105.2 102.0 9.8 18.1 114.0 47.2 34.3 85.8 157.4 111.0 114.0 116.4 113.3 190.8 135.1 65.4 126.9 57.4 145.0 176.2 122.9 57.1 58.1 131.3 132.8 90.2 112.1 44.8 49.8 117.1 64.6 41.8 65.7 104.6 116.1 159.6 57.8 120.1 182.9 64.5 107.0 139.1 0.0 0.7 1.7 3.3 2.3 2.5 8.5 4.5 3.3 1.7 6.6 6.4 7.1 0.0 1.2 8.9 3.4 10.8 2.4 6.6 6.5 5.8 13.7 6.8 7.4 6.5 6.6 6.9 6.0 6.7 6.1 1.9 0.0 2.2 1.3 13.3 14.3 10.4 29.9 2.8 6.4 6.3 8.6 12.8 0.0 12.1 5.5 0.0 74.5 5.4 10.1 5.9 10.9 24.4 15.7 7.6 5.3 1.2 134.3 8.3 7.5 103.4 11.8 10.7 6.7 8.8 32.2 3.9 2.4 27.7 10.1 6.1 14.4 32.6 1.9 5.4 8.2 3.1 5.8 3.6 1.9 2.6 1.6 0.0 1.0 1.4 10.3 2.9 4.1 32.1 5.2 3.3 12.2 16.2 1.2 6.6 0.8 11.3 114.1 113.1 15.5 10.9 22.4 9.3 12.1 30.5 11.3 UBIAD1 "SCCD, TERE1" ENSG00000120942 "UbiA prenyltransferase domain containing 1" Q9Y5Z9 1 11273198-11296049 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Menaquinone biosynthesis, Ubiquinone biosynthesis" "Prenyltransferase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044862 Approved Vesicles NA NA "Cluster 30: Non-specific - Translation" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA044862: AB_2679117" "unprognostic (1.79e-2)" "unprognostic (2.26e-1)" "unprognostic (5.06e-2)" "unprognostic (1.74e-1)" "unprognostic (7.95e-3)" "unprognostic (7.55e-2)" "unprognostic (1.16e-2)" "unprognostic (2.01e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "prognostic favorable (6.80e-5)" "unprognostic (3.00e-1)" "unprognostic (3.89e-1)" "unprognostic (2.03e-2)" "unprognostic (1.25e-1)" 7.3 7.5 5.5 7.6 7.5 7.6 8.3 6.9 7.0 6.8 2.3 7.0 5.5 8.4 6.1 5.9 9.6 4.6 8.2 5.2 6.1 6.5 10.1 6.1 10.2 7.5 7.5 11.5 10.8 10.0 5.8 6.4 6.8 7.1 6.8 8.0 7.0 6.6 17.7 8.1 6.4 7.9 6.6 7.1 7.2 9.2 7.1 11.9 7.7 13.8 10.5 8.1 5.6 10.1 14.5 14.1 11.0 21.3 8.0 7.4 14.8 15.6 12.7 16.4 14.9 16.4 13.1 28.5 15.6 11.1 15.4 19.5 28.1 18.7 19.9 20.0 24.1 19.1 14.5 22.0 14.5 29.5 15.9 11.2 24.9 22.2 26.3 8.7 12.2 25.8 23.1 22.9 11.2 14.8 19.1 14.7 13.3 27.1 20.7 18.0 24.6 34.6 12.7 9.5 13.6 14.5 16.6 16.3 21.5 4.5 12.1 15.3 10.2 14.4 15.5 15.1 20.5 18.6 27.9 52.4 9.2 38.3 18.3 11.5 12.8 19.5 24.3 17.5 27.3 45.3 32.5 24.8 16.9 42.1 48.5 33.3 3.9 20.5 15.6 21.1 33.8 22.2 5.5 7.5 6.9 7.0 5.2 6.1 7.5 7.5 6.8 6.6 7.1 10.1 9.4 9.6 14.6 4.2 19.6 15.4 16.7 11.2 22.2 11.9 13.3 13.7 8.3 11.5 18.1 5.5 8.4 10.6 17.5 7.4 11.7 10.8 34.1 6.3 9.6 9.5 4.9 13.3 4.2 13.3 14.7 11.4 13.3 9.6 7.0 11.3 7.9 19.7 8.7 13.5 6.5 11.1 14.2 8.2 14.1 23.1 12.5 9.5 5.4 4.7 7.1 9.5 14.4 9.0 11.1 11.0 5.3 10.9 14.2 15.0 5.8 8.6 8.9 15.8 0.0 20.2 10.4 24.7 15.7 15.7 12.6 18.9 14.4 12.0 14.1 10.3 UBL7 "BMSC-UbP, MGC14421" ENSG00000138629 "Ubiquitin like 7" Q96S82 15 74445977-74461182 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 175.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040423, HPA041897" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA040423: AB_10673442, HPA041897: AB_2677732" "unprognostic (4.21e-2)" "prognostic favorable (6.37e-5)" "unprognostic (2.93e-3)" "unprognostic (5.56e-2)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "unprognostic (3.43e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (6.71e-2)" "unprognostic (5.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.47e-3)" "unprognostic (8.94e-3)" "unprognostic (7.05e-2)" "unprognostic (2.75e-1)" "unprognostic (3.43e-2)" 33.8 38.4 27.0 13.5 28.9 15.9 32.9 26.7 35.0 34.0 23.9 48.1 15.0 36.8 15.4 37.8 30.3 10.6 67.9 29.4 26.9 38.1 32.0 29.7 21.4 28.2 27.3 31.1 44.7 25.0 30.3 15.6 29.2 36.4 16.5 13.1 34.2 16.3 114.6 54.3 36.9 18.4 25.5 48.2 43.5 55.8 25.9 27.3 37.0 37.8 29.6 38.7 33.1 29.0 18.7 20.3 31.6 42.3 32.4 42.1 21.8 29.8 36.0 37.6 46.6 24.7 26.4 27.2 31.1 35.9 48.6 29.4 88.4 40.4 36.5 36.0 55.6 35.8 32.2 45.3 31.7 22.4 29.1 32.9 35.5 32.1 43.0 32.3 32.0 60.8 30.9 39.3 39.3 26.2 28.1 35.3 75.7 31.2 24.6 29.4 25.0 60.5 32.6 21.2 31.1 61.8 28.8 26.8 40.1 44.1 28.6 36.7 18.8 34.6 20.4 17.4 37.5 39.8 82.1 30.5 22.7 40.3 30.6 32.9 51.6 59.7 35.1 58.5 33.7 50.5 35.3 37.1 70.6 55.3 33.9 40.6 65.3 55.5 55.5 151.5 65.6 52.1 27.0 28.9 26.7 35.0 29.4 26.9 28.2 27.3 29.2 25.5 25.9 29.0 17.3 32.1 18.2 3.9 35.4 15.8 24.1 35.6 26.7 5.8 24.9 23.9 29.9 18.6 20.0 14.7 8.4 71.1 36.8 25.5 58.7 37.3 75.3 12.7 13.0 20.7 23.4 45.8 5.7 34.7 66.9 20.7 22.4 13.5 19.0 21.5 22.5 16.3 41.9 5.0 3.8 26.9 20.3 38.3 31.4 175.8 24.5 31.4 21.4 5.6 82.6 18.2 23.7 4.0 4.5 29.5 27.6 21.1 51.6 19.5 48.9 44.6 16.1 9.0 19.7 13.5 50.5 59.2 31.1 29.8 25.1 68.4 23.0 19.6 28.0 25.2 UBTF "NOR-90, UBF, UBF1, UBF2" ENSG00000108312 "Upstream binding transcription factor" P17480 17 44205033-44221626 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004611, HPA006385" Supported Supported Enhanced "Nucleoli fibrillar center" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli fibrillar center" "CAB004611: AB_671403, HPA006385: AB_1080447" "unprognostic (1.37e-3)" "unprognostic (1.12e-3)" "unprognostic (2.54e-1)" "unprognostic (1.12e-2)" "unprognostic (3.15e-1)" "unprognostic (8.54e-3)" "unprognostic (1.35e-3)" "unprognostic (4.10e-2)" "unprognostic (5.39e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-2)" "unprognostic (2.10e-1)" "unprognostic (1.96e-3)" "unprognostic (5.44e-2)" "unprognostic (9.01e-2)" "unprognostic (1.91e-2)" "unprognostic (2.00e-1)" 34.8 36.5 36.2 44.8 33.7 54.9 35.4 38.2 37.1 50.6 30.1 49.4 33.6 50.8 27.5 41.8 41.9 32.5 38.8 35.5 32.7 38.1 36.1 32.3 67.6 34.0 34.5 41.6 41.4 38.2 33.8 29.2 32.2 41.6 28.2 23.1 37.7 40.8 63.7 47.4 42.5 36.3 31.6 49.8 34.7 20.8 34.9 73.6 46.4 36.6 51.7 45.1 41.8 35.0 69.1 104.3 77.3 93.2 49.6 56.5 72.3 70.6 46.7 70.1 52.0 50.7 54.8 250.0 69.3 65.3 51.9 63.6 99.1 59.2 57.9 145.3 109.5 100.5 73.8 83.7 32.5 192.1 85.7 56.9 52.2 44.6 65.6 67.2 58.9 108.8 117.4 75.9 58.9 113.7 188.3 75.0 73.7 46.6 81.6 184.0 104.3 112.0 40.4 54.5 119.5 90.3 70.4 62.2 54.2 47.9 89.9 120.8 75.5 109.9 133.1 65.1 95.0 66.6 61.7 151.1 64.8 86.0 100.1 9.6 5.7 6.1 15.5 6.3 16.7 11.7 10.8 16.2 6.7 14.1 12.2 13.1 9.7 15.7 11.6 12.7 10.0 11.3 36.2 33.7 38.2 37.1 35.5 32.7 34.0 34.5 32.2 31.6 34.9 35.0 41.4 41.7 42.1 14.7 57.5 20.5 19.6 17.9 57.5 88.8 31.0 29.6 44.5 35.8 32.2 38.6 79.2 30.9 60.3 41.7 35.2 27.2 2.3 39.3 57.7 42.7 47.3 61.2 8.5 40.8 40.7 38.9 23.9 48.1 31.7 43.1 32.5 26.5 25.9 26.9 8.2 32.5 12.2 18.4 13.3 3.6 36.7 27.4 23.2 8.4 38.1 33.9 54.6 3.5 10.6 28.1 30.7 50.8 42.2 17.4 26.7 25.4 26.5 57.6 52.6 48.5 45.9 5.3 44.0 52.1 24.3 32.7 53.1 40.2 32.8 11.8 UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760270-233773300 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "intestine: 201.2;liver: 322.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 105.0" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HaCaT: 14.0;OE19: 64.5;RT4: 34.7" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" 0.1 0.1 0.6 0.2 0.5 0.5 0.2 1.5 0.8 0.1 0.2 3.0 201.2 0.2 0.4 3.5 0.1 1.0 0.2 0.4 0.8 4.0 322.4 0.2 0.3 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.2 2.4 0.9 0.5 0.3 0.1 1.8 79.2 0.1 0.0 0.2 2.4 0.6 0.3 0.1 0.2 0.1 0.3 10.0 0.9 0.6 0.3 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.0 0.0 0.1 5.4 0.3 0.2 2.5 0.1 0.1 14.0 0.0 0.2 0.0 0.2 0.1 0.1 0.6 1.6 0.0 0.5 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.3 0.2 0.6 0.0 0.8 0.1 0.3 0.5 64.5 6.5 0.1 0.1 0.6 0.0 34.7 0.2 0.4 2.6 0.4 0.0 0.2 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.2 0.1 0.7 0.4 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 1.4 0.3 0.1 0.1 0.1 0.0 0.6 0.5 1.5 0.8 0.4 0.8 0.2 0.2 0.2 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.0 1.8 0.0 0.1 2.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.1 105.0 0.0 0.0 0.0 0.4 0.0 2.4 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.0 0.1 6.9 14.6 2.2 1.5 0.0 0.0 0.4 0.1 0.2 0.1 1.5 0.0 0.0 0.1 0.0 0.7 7.3 UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 71.3;liver: 143.3;urinary bladder: 88.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.5;Early spermatids: 52.4;Gastric mucus-secreting cells: 14.3;Late spermatids: 23.3;Squamous epithelial cells: 17.3" "Group enriched" "Detected in many" 5 "liver cancer: 7.2;lung cancer: 3.1;renal cancer: 7.6;urothelial cancer: 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 1194.0" "Not detected" "Not detected" "CAB009819, HPA054065, HPA056023" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "Endoplasmic reticulum" "CAB009819: AB_2241481, HPA054065: AB_2682367, HPA056023: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 1.8 0.0 1.8 5.8 0.1 2.6 16.1 0.0 3.5 0.0 0.0 0.0 71.3 143.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.1 1.3 0.0 2.6 3.6 0.0 11.1 2.6 0.0 0.0 0.0 17.4 0.4 0.0 1.2 0.5 0.0 5.8 88.8 5.5 0.0 4.2 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 53.8 1.6 0.0 80.2 0.1 0.8 294.5 0.1 4.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.3 0.0 31.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.0 1194.0 0.0 0.1 0.2 0.1 3.2 149.0 0.0 0.0 7.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.2 12.5 0.0 0.0 0.0 0.3 0.0 2.9 1.8 0.0 0.0 0.0 0.4 0.0 0.0 52.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 14.3 0.5 0.0 0.0 0.4 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 23.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.5 1.8 0.1 0.0 0.0 0.0 0.0 1.2 0.2 17.3 1.1 0.0 0.0 0.0 0.1 3.0 UGT2A1 ENSG00000173610 "UDP glucuronosyltransferase family 2 member A1 complex locus" P0DTE4 4 69588417-69653249 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Olfaction, Sensory transduction" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 3.6;kidney: 2.3;liver: 3.6;pituitary gland: 5.6" "Cell type enriched" "Detected in some" 18 "Proximal tubular cells: 107.9" "Cancer enhanced" "Detected in some" "liver cancer: 0.7;lung cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017261, HPA045108" Uncertain NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA017261: AB_10963582, HPA045108: AB_2679218" "unprognostic (3.93e-3)" "unprognostic (5.62e-1)" "unprognostic (1.28e-4)" "unprognostic (1.74e-1)" "unprognostic (2.76e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 3.7 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 UGT2B7 UGT2B9 ENSG00000171234 "UDP glucuronosyltransferase family 2 member B7" P16662 4 69051363-69112987 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "kidney: 1299.8;liver: 1612.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 150.6;Glandular and luminal cells: 234.7;Hepatocytes: 550.8;Proximal tubular cells: 1249.5" "Group enriched" "Detected in many" 7 "liver cancer: 116.4;renal cancer: 101.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 310.8" HPA045108 Uncertain NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA045108: AB_2679218" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "prognostic favorable (7.65e-5)" "unprognostic (1.11e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-2)" "unprognostic (5.41e-3)" "unprognostic (1.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.17e-3)" "unprognostic (1.98e-1)" "prognostic favorable (3.79e-4)" "unprognostic (1.08e-2)" "unprognostic (2.55e-1)" "unprognostic (6.23e-3)" "prognostic favorable (5.38e-4)" 0.2 0.0 0.0 0.3 0.0 0.0 2.3 0.0 0.0 32.0 0.0 3.8 68.7 8.9 24.2 0.2 49.9 10.4 0.0 0.0 0.0 1299.8 1612.1 0.4 0.0 0.0 0.0 0.1 9.9 0.0 0.0 0.1 0.0 0.3 6.9 0.0 3.6 27.5 0.0 0.3 66.6 0.3 0.0 0.0 0.9 0.1 0.0 0.9 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.3 0.0 0.0 77.6 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 41.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.1 0.6 0.1 310.8 2.7 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 43.2 0.0 0.0 0.0 0.2 0.3 0.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.6 1.6 0.0 0.0 1.2 0.6 0.1 38.6 2.1 125.0 0.0 0.0 0.0 5.7 97.8 6.6 0.3 150.6 14.0 1.0 3.5 2.7 0.4 10.6 0.0 0.1 0.0 234.7 0.0 0.0 8.9 550.8 0.1 0.0 0.3 37.3 0.0 13.8 0.0 0.0 1.8 7.6 3.6 0.0 0.0 0.0 0.0 1.5 0.4 13.0 10.7 0.0 0.0 0.6 70.6 1249.5 0.5 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 6.3 0.1 5.9 2.3 UGT8 CGT ENSG00000174607 "UDP glycosyltransferase 8" Q16880 4 114598770-114678225 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 266.4" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 821.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 6.9;naive B-cell: 10.7" "Lineage enriched" "Detected in single" 12 "B-cells: 10.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 58.4;OE19: 123.7;RPTEC TERT1: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014405, HPA065785" Enhanced Approved Mitochondria No No "Cluster 19: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA014405: AB_1858606, HPA065785: AB_2685559" "unprognostic (7.38e-3)" "unprognostic (2.07e-1)" "unprognostic (1.25e-2)" "unprognostic (2.38e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "unprognostic (7.78e-2)" "unprognostic (1.56e-3)" "unprognostic (4.49e-2)" "unprognostic (2.76e-1)" "prognostic favorable (8.55e-5)" "unprognostic (2.80e-1)" "unprognostic (1.78e-2)" "unprognostic (7.53e-2)" "unprognostic (1.49e-1)" 0.6 0.6 58.6 4.6 153.7 1.1 4.6 166.2 94.5 7.0 9.7 26.8 30.3 3.8 0.3 1.5 4.4 11.0 0.3 66.2 94.7 31.0 0.2 1.1 4.9 220.9 132.8 0.4 8.5 0.2 0.2 0.2 200.6 0.5 27.7 2.2 7.3 0.7 0.5 2.2 27.7 1.6 139.2 1.7 16.8 5.0 132.4 0.6 13.5 0.4 5.0 0.6 0.6 266.4 0.6 0.2 4.4 0.6 0.3 0.0 0.7 0.2 0.0 0.1 3.4 17.7 58.4 17.6 1.2 0.2 13.8 25.8 0.0 0.1 0.1 0.3 14.3 0.3 24.6 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 5.4 0.1 0.2 16.1 3.0 0.1 0.3 0.3 1.7 6.4 123.7 8.8 1.6 28.9 0.3 55.2 0.6 31.4 4.6 0.2 5.4 0.8 1.1 0.9 5.4 1.0 1.1 19.2 0.7 19.6 6.3 0.8 0.6 29.2 0.9 17.9 0.2 0.0 0.8 0.0 0.0 0.6 6.9 0.0 0.0 0.0 10.7 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.3 58.6 153.7 166.2 94.5 66.2 94.7 220.9 132.8 200.6 139.2 132.4 266.4 0.1 6.4 1.5 1.0 22.0 0.0 1.8 0.3 6.8 0.0 5.7 6.1 0.8 8.6 3.9 25.8 0.0 0.0 0.1 19.0 9.8 1.4 9.2 9.6 1.7 0.5 48.4 0.0 1.0 13.1 0.0 0.6 19.4 21.4 0.0 0.2 0.0 0.0 0.0 0.0 3.7 27.9 0.0 0.0 0.0 3.5 1.2 0.5 1.8 2.8 0.0 0.0 0.0 98.5 821.1 10.8 14.6 0.0 4.0 0.7 24.2 1.4 1.5 0.0 0.0 0.0 0.4 20.9 34.0 5.9 0.1 0.0 0.4 0.1 26.9 0.9 UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 27.0;lymphoid tissue: 67.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 49.7;Plasma cells: 21.0;Squamous epithelial cells: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Group enriched" "Detected in many" 4 "dendritic cells: 4.8;T-cells: 2.3" "Cell line enhanced" "Detected in all" "MOLT-4: 450.9;REH: 1004.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA049408: AB_2756317, HPA055446: AB_2732597" "unprognostic (3.83e-2)" "unprognostic (6.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (4.30e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.52e-5)" "unprognostic (2.33e-3)" "unprognostic (0.00e+0)" "unprognostic (3.75e-3)" "unprognostic (2.45e-1)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" 1.0 0.9 2.1 9.6 2.7 27.0 1.7 2.1 2.3 1.6 1.8 2.9 3.7 1.0 0.1 6.5 0.4 0.8 0.5 2.0 2.2 0.6 0.9 1.3 15.8 2.8 2.8 0.3 0.6 0.2 0.2 2.1 2.7 0.6 2.6 0.4 1.5 0.2 1.2 3.4 3.9 1.9 1.9 3.7 3.3 5.2 3.5 67.2 0.3 0.3 10.3 1.6 2.5 4.6 111.3 78.7 116.6 83.4 3.3 13.3 18.5 88.3 42.0 89.9 86.8 94.6 54.9 62.7 21.1 39.4 32.7 54.1 81.2 47.7 63.0 102.7 92.2 54.3 74.3 102.4 1.3 135.1 78.9 6.5 3.5 48.9 12.6 14.1 27.2 97.2 79.3 70.5 54.5 86.7 450.9 82.5 52.5 40.0 84.3 1004.5 259.7 45.4 24.9 80.1 86.0 68.5 69.2 37.7 12.1 18.8 68.2 127.6 34.2 94.6 76.7 124.3 108.3 29.8 33.1 183.5 54.8 129.7 123.3 0.3 0.2 0.1 0.6 0.0 0.0 0.2 0.8 1.0 1.3 0.1 0.2 0.8 0.8 0.5 0.2 4.8 2.3 0.6 2.1 2.7 2.1 2.3 2.0 2.2 2.8 2.8 2.7 1.9 3.5 4.6 0.2 0.0 0.0 1.6 2.1 0.0 0.8 0.0 3.4 2.5 4.4 2.8 4.3 1.5 0.6 0.0 0.0 6.6 6.9 2.6 0.0 2.2 2.9 1.3 1.8 2.2 0.0 49.7 0.4 0.4 7.8 4.7 8.6 2.4 0.0 10.4 0.4 0.7 8.9 3.3 0.4 2.3 0.0 1.9 0.0 1.8 0.6 3.8 0.0 0.0 2.0 0.6 1.0 3.0 1.3 4.2 1.9 0.4 21.0 0.6 1.4 0.2 0.7 0.7 0.0 1.2 6.1 6.1 11.9 15.8 0.0 1.4 3.7 1.5 8.3 1.3 ULK4 "FAM7C1, FLJ20574, REC01035" ENSG00000168038 "Unc-51 like kinase 4" Q96C45 3 41246599-41962130 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 352.3;Excitatory neurons: 108.6;Inhibitory neurons: 99.2;Late spermatids: 405.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017930 Uncertain Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Mitochondria, Cytosol" "HPA017930: AB_1858615" "unprognostic (3.16e-2)" "unprognostic (2.98e-3)" "unprognostic (9.72e-3)" "unprognostic (3.46e-2)" "unprognostic (2.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-1)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.75e-3)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (5.46e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (6.12e-2)" 2.7 3.1 1.6 2.9 2.1 8.5 2.5 0.4 1.7 8.5 16.9 1.6 1.2 6.6 4.5 1.5 9.0 1.9 8.6 2.3 2.5 3.9 2.1 3.5 3.0 6.9 7.6 2.1 2.0 8.0 2.9 2.7 3.9 2.2 1.7 6.0 1.7 2.4 0.4 2.1 2.0 3.5 5.6 2.0 2.4 23.4 2.5 3.0 4.9 0.4 2.7 1.9 3.7 2.1 8.3 2.9 2.8 3.8 1.1 1.7 4.8 2.7 2.7 3.2 3.0 1.0 2.3 9.5 1.6 6.3 3.5 4.1 3.7 2.1 2.9 1.5 1.0 2.1 5.7 3.3 4.1 6.5 1.8 1.6 2.3 16.1 3.2 4.4 2.2 6.4 2.1 7.5 2.3 6.4 8.1 4.9 3.4 2.1 3.4 1.7 9.1 4.5 7.2 7.6 1.6 10.3 3.1 1.3 2.8 1.8 3.1 2.0 6.6 2.0 2.4 14.2 2.5 4.5 9.0 3.9 11.5 6.3 2.5 3.7 3.7 4.0 5.0 4.3 4.1 3.7 5.3 4.5 3.3 4.7 4.0 5.7 6.6 1.8 2.3 3.3 7.7 3.0 1.6 2.1 0.4 1.7 2.3 2.5 6.9 7.6 3.9 5.6 2.5 2.1 6.4 9.6 6.9 84.9 11.2 2.0 3.0 4.0 5.2 5.6 5.7 4.6 14.8 4.3 5.1 3.7 54.2 3.1 9.9 2.0 0.0 3.4 352.3 45.3 27.4 6.0 1.8 2.1 108.6 2.4 4.1 8.7 10.2 7.5 1.3 49.6 1.8 6.6 7.3 11.8 99.2 1.2 2.0 3.1 4.0 405.2 6.5 6.9 0.0 80.6 5.9 10.4 3.1 49.8 62.0 3.0 0.7 4.1 5.1 0.9 1.1 5.9 47.3 26.7 6.6 4.4 10.5 38.9 9.6 3.3 3.7 4.2 10.8 3.6 1.9 1.2 UNC45A "GC-UNC45, SMAP-1" ENSG00000140553 "Unc-45 myosin chaperone A" Q9H3U1 15 90930180-90954093 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039228 Approved Supported "Nuclear speckles,Cytosol" NA NA 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear speckles" Cytosol "HPA039228: AB_2676402" "unprognostic (1.46e-1)" "unprognostic (3.83e-2)" "unprognostic (4.51e-2)" "unprognostic (1.97e-1)" "unprognostic (2.68e-2)" "unprognostic (1.70e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (2.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.98e-1)" "unprognostic (9.85e-2)" "prognostic favorable (7.46e-7)" "unprognostic (9.30e-2)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-2)" 25.0 25.3 7.7 16.7 8.2 17.3 23.2 8.6 9.1 32.0 10.0 41.2 16.4 38.1 11.0 31.4 28.4 17.3 15.9 7.8 7.7 18.9 13.0 20.2 18.9 8.9 11.6 26.1 22.3 33.2 17.5 19.6 9.5 25.2 13.4 5.6 25.8 34.1 9.6 37.7 23.5 28.0 8.3 19.7 28.5 13.1 9.6 18.0 19.5 10.6 17.3 39.3 29.4 8.0 38.2 76.3 30.9 27.2 83.0 38.0 27.3 42.4 36.2 56.5 45.1 61.3 49.4 44.7 55.5 53.8 32.5 82.1 52.9 54.4 26.6 49.8 75.9 86.2 77.0 44.4 46.8 21.5 56.2 47.3 65.8 55.7 40.5 54.2 77.5 35.1 38.6 35.8 43.3 62.2 28.1 18.6 41.8 69.5 38.0 54.8 46.9 48.1 38.4 89.2 43.1 39.4 57.1 55.9 54.3 36.8 50.8 44.3 77.0 48.0 34.1 40.4 45.0 33.6 50.5 21.1 46.6 49.7 49.8 11.5 8.3 5.0 11.8 7.3 11.3 7.9 9.6 9.1 10.4 6.3 7.8 7.4 1.6 9.8 11.6 9.1 9.3 9.8 7.7 8.2 8.6 9.1 7.8 7.7 8.9 11.6 9.5 8.3 9.6 8.0 21.7 22.4 22.4 9.4 23.2 16.3 24.8 26.1 30.1 27.2 17.2 19.6 12.7 35.8 23.8 18.4 18.8 53.6 17.5 26.9 13.7 33.6 26.7 12.8 20.3 25.3 37.0 25.2 19.1 18.2 22.7 23.7 26.5 22.1 29.2 30.9 18.9 13.4 28.2 18.5 18.4 15.9 26.4 12.2 14.0 29.0 29.5 20.7 19.6 9.4 28.8 21.5 27.8 7.1 11.0 23.3 26.0 51.6 20.6 16.8 22.0 19.6 11.7 35.1 32.9 15.2 33.9 24.8 6.4 33.9 18.8 46.2 21.4 26.0 22.7 20.3 UNC5C ENSG00000182168 "Unc-5 netrin receptor C" O95185 4 95162504-95549206 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 2078.8" "Cancer enriched" "Detected in many" 4 "thyroid cancer: 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 82.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.55e-1)" "unprognostic (2.72e-1)" "unprognostic (1.35e-2)" "unprognostic (8.45e-2)" "unprognostic (3.03e-1)" "unprognostic (3.20e-1)" "unprognostic (3.48e-1)" "unprognostic (3.40e-1)" "unprognostic (3.12e-1)" "unprognostic (1.11e-3)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (2.70e-5)" "unprognostic (1.25e-2)" "unprognostic (1.16e-1)" "unprognostic (1.86e-1)" "unprognostic (3.62e-4)" 1.9 9.0 8.9 1.0 17.2 0.0 1.3 7.0 17.4 1.8 0.0 2.9 1.4 2.4 1.7 0.6 1.9 2.0 3.1 6.6 15.4 1.1 1.0 2.5 0.5 18.1 8.7 2.8 0.3 0.1 1.2 1.8 21.4 3.3 3.4 6.4 6.3 3.9 0.1 0.2 1.9 2.0 8.0 4.2 2.1 2.6 16.4 1.9 11.9 0.4 0.3 2.6 1.6 40.5 0.0 0.5 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.2 4.2 0.0 0.2 0.0 1.1 0.2 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.6 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 82.9 0.0 0.0 0.2 4.8 0.3 12.3 0.0 0.1 1.2 0.0 7.9 0.0 0.0 0.0 0.1 9.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 17.2 7.0 17.4 6.6 15.4 18.1 8.7 21.4 8.0 16.4 40.5 0.7 0.0 0.0 105.4 0.0 0.1 0.1 0.1 0.0 1.9 0.7 1.5 1.7 0.0 0.2 1.8 0.0 0.5 0.0 2.6 0.0 0.0 0.7 0.5 3.4 0.7 1.2 0.0 326.1 0.0 0.1 4.6 0.0 1.2 0.0 20.2 0.4 0.0 1.8 0.0 448.3 0.5 0.0 0.8 0.0 0.8 21.1 0.4 1.8 57.1 0.0 1.3 0.0 308.1 2078.8 0.0 26.9 11.7 0.0 0.3 0.0 0.1 0.0 12.5 6.6 0.3 4.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 1.1 0.0 UPB1 BUP1 ENSG00000100024 "Beta-ureidopropionase 1" Q9UBR1 22 24494107-24528390 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 216.0" "Group enriched" "Detected in many" 5 "Hepatocytes: 146.5;Proximal tubular cells: 68.5" "Cancer enriched" "Detected in some" 8 "liver cancer: 25.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.8" "Group enriched" "Detected in some" 14 "basophil: 2.1;neutrophil: 2.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.1" "Cell line enriched" "Detected in single" 7 "CACO-2: 3.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA000728, HPA076321" Enhanced NA NA 1400000 "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000728: AB_1080471, HPA076321: " "unprognostic (7.27e-2)" "unprognostic (4.57e-3)" "unprognostic (2.27e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (1.09e-4)" "prognostic favorable (2.30e-7)" "unprognostic (8.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.93e-1)" "unprognostic (4.89e-6)" "unprognostic (3.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (1.99e-1)" "unprognostic (4.63e-3)" 0.2 0.2 0.2 0.2 0.6 2.0 0.1 0.7 1.8 0.2 0.2 0.2 1.2 0.2 0.2 0.1 0.3 0.1 1.9 0.2 0.0 25.7 216.0 0.8 0.2 0.1 0.1 0.2 0.1 0.0 0.4 0.0 0.4 0.3 0.1 1.1 0.1 0.1 0.5 0.9 0.4 0.1 0.0 0.8 0.2 3.0 0.4 0.6 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.4 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.7 1.8 0.2 0.0 0.1 0.1 0.4 0.0 0.4 0.1 0.8 0.0 2.0 0.3 0.6 0.6 1.3 0.1 0.0 4.0 0.3 0.3 2.4 4.3 0.0 1.8 10.4 0.1 0.1 0.0 11.7 0.1 1.2 0.2 0.6 1.9 2.4 5.3 0.7 0.4 0.1 1.4 0.0 0.5 0.0 0.6 3.6 146.5 0.1 0.0 1.2 0.0 0.0 5.1 2.7 1.4 0.3 1.0 0.0 0.0 21.3 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.7 1.2 0.0 68.5 0.0 1.8 0.0 2.7 3.7 12.8 6.8 0.0 1.1 0.3 0.9 0.2 0.1 1.1 URI1 "C19orf2, FLJ10575, NNX3, PPP1R19, RMP, URI" ENSG00000105176 "URI1 prefoldin like chaperone" O94763 19 29923644-30016612 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Protein phosphatase inhibitor, Repressor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 499.7;Late spermatids: 514.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071709 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA071709: AB_2686434" "unprognostic (4.22e-2)" "unprognostic (2.75e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.96e-2)" "unprognostic (2.98e-1)" "unprognostic (1.40e-3)" "unprognostic (8.12e-2)" "unprognostic (1.26e-2)" "unprognostic (4.42e-3)" "unprognostic (1.57e-1)" "unprognostic (3.71e-1)" "unprognostic (1.33e-1)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (1.42e-1)" "unprognostic (4.47e-2)" 25.0 30.6 29.7 24.8 39.6 36.4 36.7 57.8 40.7 27.9 21.0 26.1 23.5 34.2 32.3 28.5 30.2 25.1 28.1 25.0 36.8 25.6 30.5 22.9 39.9 35.9 32.3 44.1 21.9 31.4 11.0 24.1 34.5 37.7 32.1 32.4 27.2 30.4 52.8 44.9 23.4 22.8 28.4 30.0 25.0 51.6 30.9 31.7 55.4 36.2 37.3 24.8 10.7 45.6 64.8 85.9 39.5 61.7 27.5 39.8 66.5 41.3 34.4 29.5 33.7 45.4 41.5 99.7 79.4 48.2 23.4 44.6 84.8 52.7 66.5 69.7 48.5 90.8 44.3 59.7 39.7 88.5 37.3 35.1 70.6 25.7 95.7 31.7 22.1 58.2 109.7 27.2 37.4 55.3 58.0 37.1 37.1 83.4 26.2 56.7 73.2 40.5 19.4 75.3 63.4 49.7 47.1 56.3 62.2 41.7 23.5 54.8 29.1 72.1 63.9 35.6 63.3 74.4 86.2 67.7 35.5 76.5 44.4 3.4 1.3 1.8 2.9 1.4 2.5 1.9 2.6 3.0 1.1 4.5 3.1 3.1 0.1 2.2 1.4 1.6 2.2 0.8 29.7 39.6 57.8 40.7 25.0 36.8 35.9 32.3 34.5 28.4 30.9 45.6 51.6 44.8 38.8 59.1 48.6 57.0 95.3 19.4 40.5 60.6 67.6 68.1 52.8 48.6 28.2 40.5 25.0 19.2 84.4 21.7 105.7 16.9 499.7 48.5 82.8 32.5 28.9 38.5 79.9 27.8 28.7 45.6 41.3 41.8 30.9 54.5 31.8 50.9 15.4 52.2 122.3 36.5 18.3 33.6 24.0 514.0 43.8 32.9 32.0 74.9 25.0 58.5 70.0 137.7 178.4 19.4 23.7 41.3 53.3 123.9 19.4 85.2 38.8 59.8 13.1 82.3 48.5 72.2 52.2 44.8 73.6 13.1 74.2 91.6 37.0 94.3 USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381711 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 168.3" "Group enriched" "Detected in many" 5 "Early spermatids: 460.0;Late spermatids: 1094.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 14.5;U-266/70: 56.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA006777: AB_1080507, HPA007222: AB_1080505" "unprognostic (6.83e-2)" "unprognostic (2.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-3)" "unprognostic (8.02e-3)" "unprognostic (7.33e-2)" "prognostic favorable (3.09e-11)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (2.66e-2)" 7.0 13.4 11.9 1.6 22.6 1.9 4.1 18.8 19.0 6.0 32.7 10.2 13.9 5.2 5.7 9.8 11.6 2.3 73.5 18.6 9.4 53.4 18.9 3.4 0.1 12.0 13.1 6.2 18.1 24.2 18.9 1.3 7.7 4.1 6.0 76.2 7.6 3.0 168.3 12.8 17.4 6.8 8.2 0.6 6.2 86.5 15.1 0.6 3.8 62.8 0.6 4.5 4.8 17.5 6.0 0.5 0.9 3.2 0.1 0.2 1.3 0.7 0.4 0.0 0.6 6.1 0.8 10.2 1.8 1.1 1.4 1.0 7.9 2.9 0.2 7.2 1.0 2.8 4.4 12.5 2.7 0.0 2.8 0.9 0.6 0.7 2.0 1.3 0.6 7.6 14.5 0.8 1.7 4.1 0.0 0.6 1.6 2.0 1.3 0.1 2.1 1.5 4.6 0.3 11.9 3.6 3.4 2.6 0.7 1.7 8.8 6.2 0.0 0.0 1.5 0.8 1.0 56.9 13.5 0.2 0.1 2.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 22.6 18.8 19.0 18.6 9.4 12.0 13.1 7.7 8.2 15.1 17.5 0.6 3.2 2.7 10.7 0.6 2.4 5.3 1.5 1.2 75.2 3.3 2.4 85.2 7.2 6.1 5.5 95.9 0.5 1.6 25.5 113.5 3.1 460.0 39.0 3.0 3.6 0.0 0.4 15.7 1.6 0.9 7.4 2.0 8.4 0.0 2.0 2.2 23.0 17.2 10.1 11.6 2.0 0.0 1.3 2.9 1094.1 6.5 2.1 0.0 1.9 0.0 49.7 0.0 8.0 12.5 1.2 11.8 7.2 0.1 1.1 41.3 41.6 35.0 140.0 19.7 43.3 24.0 50.5 16.5 12.9 4.0 1.4 1.3 0.5 2.6 2.9 USP5 IsoT ENSG00000111667 "Ubiquitin specific peptidase 5" P45974 12 6852148-6866632 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006756 Uncertain Approved Nucleoplasm,Cytosol NA NA 1200000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA006756: AB_1080534" "unprognostic (2.19e-1)" "unprognostic (5.83e-2)" "unprognostic (2.48e-1)" "unprognostic (2.57e-1)" "unprognostic (7.60e-2)" "unprognostic (2.21e-2)" "unprognostic (4.02e-2)" "unprognostic (3.93e-2)" "unprognostic (2.57e-1)" "unprognostic (4.71e-2)" "unprognostic (8.90e-3)" "unprognostic (4.69e-2)" "unprognostic (1.17e-2)" "unprognostic (2.65e-2)" "unprognostic (3.56e-1)" "unprognostic (3.23e-1)" "unprognostic (2.02e-3)" 27.1 37.9 23.7 26.7 26.1 22.8 19.5 15.5 38.0 24.1 2.4 31.3 25.3 31.5 17.4 38.2 25.9 18.5 33.0 25.3 33.6 20.1 23.1 20.5 29.2 31.0 31.3 19.4 17.8 41.4 27.8 25.4 38.8 26.5 22.2 15.7 20.0 29.6 66.7 48.1 26.1 35.5 15.0 21.2 22.9 40.9 28.9 36.5 26.7 42.5 29.4 29.8 24.2 29.0 88.1 135.7 88.4 100.4 59.0 53.9 113.4 93.0 70.9 109.2 78.8 129.4 84.9 105.7 47.6 98.5 86.5 75.2 98.6 92.7 69.5 198.6 84.0 97.1 105.5 71.0 45.8 88.5 97.2 55.6 52.9 94.8 64.9 72.9 94.8 41.7 85.4 40.9 91.1 97.4 132.9 44.4 172.8 89.3 56.5 103.4 115.5 73.5 62.9 84.5 48.5 97.4 63.5 96.3 41.1 110.6 38.3 72.4 92.4 91.5 109.1 70.4 117.6 49.0 124.5 163.8 102.1 55.3 91.3 5.4 19.3 8.3 24.3 25.1 23.1 15.0 21.7 20.8 28.4 13.9 20.1 20.9 1.3 17.6 24.4 20.5 19.9 27.7 23.7 26.1 15.5 38.0 25.3 33.6 31.0 31.3 38.8 15.0 28.9 29.0 11.3 9.6 13.1 7.5 14.0 11.6 11.4 18.0 8.6 18.7 13.1 10.8 9.5 17.2 11.5 22.0 60.5 45.9 14.8 21.5 11.7 28.1 14.7 10.6 14.7 15.3 16.7 19.4 11.5 20.5 30.7 16.6 10.2 13.7 14.7 29.6 11.4 22.2 28.4 40.4 11.9 19.3 14.2 13.0 7.4 19.2 23.0 10.9 16.0 9.4 32.4 16.0 13.4 6.0 11.9 20.2 17.4 33.8 14.1 10.3 22.5 18.5 7.9 16.2 32.9 13.3 17.2 51.7 25.6 17.6 15.5 52.8 15.4 27.6 27.5 7.9 UTP18 "CGI-48, WDR50" ENSG00000011260 "UTP18 small subunit processome component" Q9Y5J1 17 51260546-51297936 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.6;Late spermatids: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052378 Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nucleoli rim" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear membrane" "HPA052378: AB_2681805" "unprognostic (1.36e-2)" "unprognostic (1.00e-1)" "prognostic favorable (3.33e-4)" "unprognostic (2.62e-2)" "unprognostic (2.55e-2)" "unprognostic (5.99e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.47e-2)" "unprognostic (8.37e-3)" "unprognostic (1.10e-2)" "unprognostic (8.82e-2)" "unprognostic (2.75e-2)" "unprognostic (3.11e-3)" "unprognostic (9.51e-2)" "unprognostic (1.59e-1)" "unprognostic (8.72e-3)" "unprognostic (1.93e-2)" 17.9 20.1 12.6 24.9 13.7 40.0 25.8 19.1 15.7 18.8 14.2 17.5 17.8 15.7 15.8 21.0 17.5 12.8 10.2 13.2 13.8 21.8 22.3 17.3 33.1 13.0 12.3 23.8 21.3 23.3 20.4 26.3 13.6 16.2 18.7 17.5 17.4 14.2 24.4 32.3 16.5 12.9 13.0 24.5 18.1 58.7 13.2 27.7 24.4 16.2 34.4 24.8 18.0 15.6 90.5 87.7 54.6 50.3 35.1 52.2 142.2 48.9 40.2 83.5 79.7 55.4 49.3 113.5 67.8 36.6 89.0 48.1 89.7 52.0 123.3 74.8 117.0 119.4 52.6 97.3 48.0 127.9 56.4 33.9 39.5 71.1 57.0 42.1 50.7 55.6 98.7 50.6 63.5 56.1 115.6 86.9 78.5 127.5 91.8 103.2 124.2 89.4 61.3 59.1 60.7 76.9 56.7 66.6 114.7 67.4 82.3 64.4 44.7 85.3 71.8 71.1 102.9 97.4 192.5 131.5 53.0 87.6 62.4 19.0 48.2 27.9 40.2 46.9 49.9 54.1 50.7 49.2 55.9 52.4 53.6 51.1 8.2 40.0 49.0 35.0 56.8 56.2 12.6 13.7 19.1 15.7 13.2 13.8 13.0 12.3 13.6 13.0 13.2 15.6 20.6 16.0 23.4 11.8 37.4 60.2 62.9 40.6 33.0 15.6 19.6 17.9 4.4 20.0 25.2 14.7 14.6 66.7 27.4 11.4 39.2 38.4 190.6 26.3 27.3 25.1 16.1 20.8 18.5 46.9 71.2 24.5 14.3 24.1 31.7 19.6 8.9 17.1 62.8 10.1 18.0 20.7 34.6 37.7 26.1 182.0 26.8 33.3 23.2 15.0 42.2 21.3 25.7 17.6 24.6 34.2 16.3 22.2 24.2 50.2 13.8 37.5 38.8 11.8 13.1 24.8 35.7 140.2 104.5 27.7 52.7 79.6 30.4 30.8 25.3 48.1 VAMP8 EDB ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 873.4;NB-4: 1362.5;U-937: 912.8" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" 74.0 34.7 26.9 148.4 28.2 299.7 225.1 28.7 53.8 121.8 51.6 250.6 229.9 30.6 144.5 303.1 166.1 119.2 24.6 26.5 29.9 280.1 247.4 266.5 212.4 35.6 31.6 10.4 182.5 270.3 33.7 265.7 34.3 107.7 300.9 4.4 322.5 90.4 24.3 210.2 252.1 71.4 31.9 175.9 228.4 23.4 35.5 173.5 126.0 27.3 311.7 198.0 150.0 36.5 255.0 33.2 2.6 2.3 2.4 1.4 241.6 0.7 0.3 0.2 0.3 191.2 225.2 56.8 174.4 1.2 17.9 175.2 2.4 451.6 0.6 232.3 173.7 290.3 104.4 220.7 3.3 873.4 287.1 2.3 317.5 0.3 72.3 1.2 58.2 1.2 214.9 11.6 103.8 363.9 0.8 1362.5 3.2 315.9 26.0 5.2 8.9 381.7 516.9 384.3 8.4 2.9 120.9 628.3 19.4 126.3 231.4 665.4 113.9 0.3 15.3 2.9 2.7 3.0 151.1 340.0 2.6 912.8 1.1 601.3 868.6 328.4 469.3 740.3 455.6 519.3 537.0 463.3 787.3 508.3 423.2 442.0 52.4 556.3 460.0 2135.6 665.3 1536.0 26.9 28.2 28.7 53.8 26.5 29.9 35.6 31.6 34.3 31.9 35.5 36.5 39.4 371.8 283.2 1.3 147.7 259.1 303.3 800.9 164.4 1.2 289.7 251.7 6.3 356.0 662.1 366.0 0.0 980.8 447.1 832.3 765.0 630.7 28.0 231.3 22.8 46.1 129.1 147.4 0.1 730.0 460.4 35.6 188.6 212.9 269.4 3.3 163.1 314.8 1191.1 0.0 0.1 391.8 545.3 1000.4 488.7 49.1 9.3 537.2 352.2 2.8 686.1 7.9 375.9 0.0 0.5 865.5 843.2 7.5 103.0 302.7 1184.0 1046.8 600.5 2.0 46.0 21.4 56.5 48.0 8.3 239.8 329.7 877.8 219.5 13.8 299.4 602.0 VANGL1 STB2 ENSG00000173218 "VANGL planar cell polarity protein 1" Q8TAA9 1 115641970-115698224 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 6.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.3;NK-cells: 6.2;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025235, CAB076375" Approved Approved "Plasma membrane" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB076375: AB_2665604, HPA025235: AB_1858718" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "prognostic favorable (7.53e-4)" "unprognostic (9.94e-2)" "unprognostic (1.71e-2)" "unprognostic (5.18e-2)" "unprognostic (2.18e-3)" "unprognostic (5.11e-3)" "unprognostic (2.11e-1)" "unprognostic (6.43e-3)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.88e-2)" "unprognostic (1.74e-2)" "unprognostic (7.71e-3)" "unprognostic (1.21e-1)" "unprognostic (4.50e-3)" "unprognostic (9.06e-3)" 4.9 3.9 2.1 3.8 1.2 2.5 3.2 0.8 1.1 9.1 3.0 6.8 3.8 5.5 4.9 10.4 12.0 3.8 5.4 1.3 1.3 5.3 3.0 4.1 2.1 1.2 3.0 4.4 5.0 5.2 0.5 3.6 1.7 4.4 6.4 1.6 6.4 4.5 0.9 6.8 3.9 7.3 1.2 2.2 5.5 5.0 6.5 7.3 7.6 2.4 2.5 6.4 4.4 1.0 49.6 20.7 6.6 8.9 24.1 21.5 13.1 18.8 13.5 24.1 19.1 12.0 24.1 0.0 31.5 21.9 22.7 60.9 11.2 33.3 15.8 57.9 13.7 27.4 18.4 9.8 8.8 8.2 11.4 11.4 23.1 17.2 18.2 12.8 24.1 45.9 16.8 14.8 24.5 65.7 41.0 3.4 16.7 28.8 19.5 0.1 19.1 14.3 11.0 32.8 5.9 8.0 33.9 22.2 15.4 12.4 11.3 8.8 26.2 16.5 25.7 36.3 34.6 2.1 2.3 0.2 22.3 14.3 41.1 0.0 0.5 0.0 1.9 0.3 0.5 0.2 1.2 1.9 2.3 0.0 0.4 2.0 0.0 6.2 0.5 2.0 3.0 1.0 2.1 1.2 0.8 1.1 1.3 1.3 1.2 3.0 1.7 1.2 6.5 1.0 9.2 3.2 3.2 5.5 0.5 7.4 7.4 16.8 11.4 5.2 4.6 4.6 7.9 2.8 9.6 9.2 39.6 5.0 3.4 11.2 0.0 15.7 6.1 25.1 7.7 10.5 6.7 13.2 0.9 13.8 7.3 10.1 8.2 17.0 0.0 5.1 28.9 2.5 4.3 0.0 0.7 8.6 10.2 1.9 1.4 3.0 5.9 2.9 0.0 4.7 11.1 4.7 9.2 2.0 0.1 20.8 6.1 8.2 1.8 8.3 2.6 5.6 12.8 0.9 6.6 4.3 8.5 5.5 7.0 20.0 6.5 0.4 3.1 3.2 10.3 6.5 VASN SLITL2 ENSG00000168140 Vasorin Q6EMK4 16 4371848-4383538 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 58.7;Fibroblasts: 104.2;Leydig cells: 50.1;Peritubular cells: 60.9;Sertoli cells: 98.6;Smooth muscle cells: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 21.8;MCF7: 18.4;U-2197: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011246, HPA016992" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted - unknown location" NA Yes 2000000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "Nucleoplasm, Nucleoli" "HPA011246: AB_1858720, HPA016992: AB_2732418" "unprognostic (2.20e-1)" "unprognostic (2.75e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.35e-3)" "unprognostic (8.91e-3)" "unprognostic (3.15e-3)" "unprognostic (5.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.82e-3)" "unprognostic (4.23e-2)" "unprognostic (4.95e-3)" "unprognostic (5.27e-2)" 55.7 15.5 1.5 5.8 2.3 2.7 31.5 0.8 2.3 48.1 3.0 12.1 3.4 30.3 0.0 34.1 24.6 7.3 30.5 1.1 0.5 56.1 31.8 44.9 2.8 6.3 5.5 40.0 10.3 0.0 12.8 10.4 1.7 17.9 0.0 0.3 15.9 0.0 6.9 38.8 11.2 0.0 1.6 13.0 13.4 16.8 4.6 0.0 26.8 0.0 0.0 26.5 38.9 2.7 4.2 0.0 0.6 0.5 0.2 0.2 12.6 21.8 0.1 0.0 0.0 1.9 5.5 0.0 4.5 0.3 2.6 0.3 0.0 0.0 0.0 13.7 2.2 0.9 15.9 14.9 0.6 0.0 0.4 7.9 0.0 0.3 0.0 3.1 0.0 0.1 3.1 0.8 0.0 18.4 1.0 5.3 2.2 0.4 2.4 1.0 0.0 0.0 0.0 0.1 1.4 9.3 6.5 13.5 0.6 2.2 6.8 2.5 0.0 17.5 12.5 78.4 4.6 0.0 0.0 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.3 0.8 2.3 1.1 0.5 6.3 5.5 1.7 1.6 4.6 2.7 10.0 6.4 13.1 5.5 1.4 9.6 7.8 4.2 9.1 0.5 21.9 10.9 16.2 32.9 6.4 23.9 0.0 5.4 2.8 1.5 7.9 13.1 1.1 12.1 58.7 4.6 0.0 0.0 1.1 2.9 7.2 104.2 16.8 20.5 3.8 4.6 2.9 15.3 3.4 0.0 0.9 2.0 2.0 0.6 21.7 2.8 50.1 2.0 14.2 2.8 0.0 18.3 0.0 0.5 0.3 28.3 1.2 60.9 0.8 6.4 0.2 12.3 2.7 0.7 98.6 12.6 80.9 0.8 4.1 3.7 7.5 10.0 3.5 2.3 0.8 4.9 VAT1 "FLJ20230, VATI" ENSG00000108828 "Vesicle amine transport 1" Q99536 17 43014607-43025123 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 133.2;Hofbauer cells: 146.4;Melanocytes: 122.7" "Cancer enhanced" "Detected in all" "melanoma: 295.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 104.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 104.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 680.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045170 Uncertain NA NA 2700000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA045170: AB_10964166" "unprognostic (2.22e-2)" "unprognostic (4.41e-3)" "unprognostic (6.86e-3)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (9.67e-2)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.16e-2)" "unprognostic (5.56e-2)" "unprognostic (1.86e-2)" "unprognostic (1.17e-3)" "unprognostic (2.38e-1)" "prognostic favorable (5.89e-4)" "unprognostic (1.71e-2)" "unprognostic (3.66e-2)" "unprognostic (1.07e-1)" "unprognostic (3.36e-2)" 180.4 251.5 53.6 32.1 57.6 86.5 137.5 55.3 67.3 160.8 54.8 97.5 25.7 121.4 65.0 132.6 78.4 85.6 74.7 47.3 129.9 70.5 44.5 111.7 29.0 88.4 132.3 184.8 67.2 54.7 103.7 83.9 173.9 64.9 32.9 7.6 86.3 52.2 29.2 194.3 65.1 94.2 60.5 40.3 56.1 79.2 93.3 63.7 68.3 45.8 33.7 109.5 126.3 77.3 38.9 225.0 53.6 119.0 556.9 435.5 75.5 94.2 282.1 89.7 167.1 139.7 83.2 7.7 128.8 395.8 283.7 58.9 94.1 81.6 82.7 14.4 127.6 36.2 107.3 279.5 357.7 177.6 271.5 234.3 119.2 154.0 71.2 203.8 428.9 230.5 77.3 12.1 227.3 37.2 262.2 76.6 68.1 111.6 106.2 37.3 66.1 19.4 102.2 76.6 50.0 94.6 51.3 29.5 680.8 217.9 82.5 99.4 431.7 199.9 92.5 226.2 22.9 19.4 30.2 14.3 203.1 132.0 31.4 104.0 16.6 24.9 13.1 7.9 15.3 19.9 18.5 13.6 8.4 19.5 16.8 10.4 5.1 11.1 9.2 4.1 13.4 19.0 53.6 57.6 55.3 67.3 47.3 129.9 88.4 132.3 173.9 60.5 93.3 77.3 133.2 22.4 13.9 1.0 17.2 28.4 14.2 17.9 34.1 1.1 29.5 30.2 31.6 17.2 10.7 23.9 4.2 6.5 6.5 9.2 17.6 99.7 27.5 14.2 32.5 71.0 15.1 12.6 2.3 43.4 45.1 91.4 8.2 32.6 77.2 93.8 73.9 15.8 146.4 5.0 2.4 4.1 4.1 40.0 32.4 45.2 51.9 43.9 122.7 6.5 16.1 4.2 3.1 3.5 4.1 49.6 10.4 58.6 19.6 25.5 36.5 60.1 12.6 1.8 13.1 19.4 39.1 12.8 15.5 35.1 33.5 11.1 12.6 31.2 4.7 21.8 VAV3 ENSG00000134215 "Vav guanine nucleotide exchange factor 3" Q9UKW4 1 107571161-107965180 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 83.9" "Cell type enhanced" "Detected in many" "Astrocytes: 263.5;Basal squamous epithelial cells: 163.9;Syncytiotrophoblasts: 246.0" "Cancer enhanced" "Detected in all" "breast cancer: 28.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 52.8;RH-30: 61.7;RPTEC TERT1: 86.2;T-47d: 107.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002012 Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB002012: " "unprognostic (4.80e-3)" "unprognostic (7.99e-3)" "unprognostic (5.31e-3)" "unprognostic (3.78e-3)" "unprognostic (1.15e-1)" "unprognostic (1.67e-3)" "unprognostic (6.84e-2)" "unprognostic (2.34e-2)" "unprognostic (3.39e-2)" "unprognostic (1.88e-2)" "unprognostic (2.25e-1)" "unprognostic (2.34e-1)" "prognostic favorable (4.60e-8)" "unprognostic (1.89e-1)" "unprognostic (2.21e-1)" "unprognostic (7.47e-2)" "unprognostic (1.23e-2)" 3.1 1.7 4.1 10.8 4.4 19.3 34.1 5.9 7.1 6.9 15.4 41.2 9.3 4.5 4.0 34.9 3.7 2.6 1.5 2.2 3.5 83.9 2.4 4.1 10.4 4.2 7.1 0.5 17.4 1.5 1.4 34.3 4.3 4.3 50.9 7.4 7.3 11.5 0.9 49.0 15.2 3.6 1.5 11.2 7.2 5.1 9.2 8.8 9.9 1.2 16.6 12.7 16.1 3.0 0.0 12.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 3.5 16.9 0.6 0.2 0.0 0.0 4.5 17.4 5.8 10.2 0.0 16.3 6.5 0.0 36.6 0.0 1.1 0.0 0.0 8.5 0.0 13.3 0.2 5.7 34.2 4.2 5.0 0.2 1.2 52.8 61.7 0.4 86.2 29.5 2.8 2.6 16.4 7.2 0.3 1.5 107.2 29.7 1.2 0.6 0.0 0.1 0.6 8.0 3.3 0.5 13.0 26.1 1.2 4.7 0.6 0.7 2.1 0.5 1.1 1.7 0.6 1.0 2.6 2.0 0.1 1.4 1.7 2.1 0.2 1.6 2.6 0.7 4.1 4.4 5.9 7.1 2.2 3.5 4.2 7.1 4.3 1.5 9.2 3.0 7.3 0.0 1.7 263.5 37.0 11.7 10.3 13.3 163.9 15.0 48.5 21.5 2.4 5.7 17.8 51.5 2.1 108.8 91.0 87.3 117.4 7.9 55.7 11.2 1.1 9.6 21.1 11.3 38.2 0.0 25.6 3.1 2.6 5.8 7.6 0.0 10.0 0.2 23.6 0.0 77.7 29.1 4.1 15.7 10.6 40.1 0.3 22.1 3.6 23.4 13.3 3.8 69.0 36.2 2.4 0.1 47.2 0.4 32.7 2.1 25.2 79.6 12.3 28.4 6.6 51.1 1.6 1.3 3.0 108.7 21.0 246.0 30.3 8.8 45.9 4.7 VAX2 DRES93 ENSG00000116035 "Ventral anterior homeobox 2" Q9UIW0 2 70900576-70965373 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.4;retina: 11.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.5;Cone photoreceptor cells: 16.7;Horizontal cells: 11.8;Muller glia cells: 7.6;Rod photoreceptor cells: 19.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 4.7;MCF7: 5.6;RH-30: 4.6;SCLC-21H: 4.6;SH-SY5Y: 5.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 3.2" HPA009708 Approved "Nuclear speckles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear speckles" "HPA009708: AB_2668261" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.96e-2)" "unprognostic (3.16e-2)" "unprognostic (1.63e-2)" "unprognostic (2.17e-1)" "unprognostic (3.52e-2)" "unprognostic (7.23e-3)" "unprognostic (2.42e-1)" "unprognostic (1.98e-1)" "unprognostic (3.81e-1)" "unprognostic (2.16e-1)" "unprognostic (7.74e-3)" "unprognostic (6.63e-3)" "unprognostic (4.65e-1)" "unprognostic (6.67e-3)" "unprognostic (2.18e-2)" 1.5 0.4 1.8 0.1 1.0 0.0 1.1 5.4 1.6 0.9 0.6 0.6 0.0 1.0 0.0 0.4 0.7 0.0 0.6 1.9 2.6 0.4 0.0 0.5 0.0 0.9 1.0 0.7 1.2 0.2 0.9 0.2 1.0 0.7 0.0 11.1 0.8 0.0 0.5 1.2 0.3 0.3 0.7 0.0 0.2 0.2 1.6 0.0 0.2 0.1 0.0 0.5 0.4 1.0 1.5 3.6 0.8 4.7 1.2 0.7 2.6 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.5 0.2 1.8 0.0 0.1 0.0 3.0 0.0 0.0 2.1 0.6 0.0 0.0 1.2 0.0 0.2 0.0 1.3 0.4 0.2 0.0 0.0 1.8 5.6 0.0 0.0 2.0 0.0 0.0 0.0 4.6 0.0 1.5 1.2 4.6 5.6 3.7 0.0 2.1 0.1 2.1 0.2 0.9 2.2 0.5 1.1 0.9 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.0 5.4 1.6 1.9 2.6 0.9 1.0 1.0 0.7 1.6 1.0 3.2 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 9.5 1.4 1.4 0.1 0.0 0.1 0.0 16.7 0.1 0.1 0.2 1.9 1.2 0.1 0.0 0.1 1.5 0.0 0.0 0.6 0.6 0.4 1.4 0.0 0.0 0.0 0.0 1.1 0.1 0.0 11.8 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.8 0.0 4.2 7.6 0.0 2.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 19.5 0.0 0.8 0.8 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.1 0.0 VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 22.0;Leydig cells: 13.7;Microglial cells: 36.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 146.5;HBF TERT88: 114.4;hTEC/SVTERT24-B: 116.5;LHCN-M2: 129.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 25.0 6.9 2.6 4.2 2.5 0.2 16.7 2.7 2.8 9.7 2.1 4.7 2.4 7.3 1.8 4.0 8.5 6.8 12.7 2.4 2.4 6.7 4.2 16.8 8.0 3.1 2.8 5.9 1.8 2.7 1.5 19.3 2.9 5.1 3.3 1.2 7.4 5.0 3.1 5.1 6.8 6.6 2.6 3.9 3.2 1.4 3.7 1.1 27.7 4.1 3.4 10.3 7.6 2.5 5.9 2.8 1.8 0.0 25.5 25.3 0.0 146.5 87.3 79.2 62.5 0.0 0.7 0.0 0.0 82.7 33.1 4.4 1.3 54.8 114.4 0.1 2.8 0.0 3.8 0.0 13.9 0.0 0.0 27.0 2.5 116.5 80.5 79.3 49.7 0.0 0.0 0.0 129.9 2.1 0.0 0.0 1.3 0.0 47.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 2.3 3.3 0.1 0.7 0.7 0.2 24.2 83.6 9.2 20.8 42.1 0.2 0.0 0.0 34.9 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 2.5 2.7 2.8 2.4 2.4 3.1 2.8 2.9 2.6 3.7 2.5 39.3 3.2 0.0 10.1 0.1 2.4 1.3 3.2 0.0 1.0 3.2 1.7 1.5 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 3.1 8.3 10.9 22.0 0.0 0.0 2.0 0.0 0.0 9.1 0.0 11.0 0.0 8.5 10.0 0.0 0.3 1.7 2.0 0.0 4.1 0.3 2.2 1.2 13.7 0.4 3.6 36.5 0.0 3.4 0.0 1.5 0.6 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.2 0.0 1.9 11.7 0.2 2.0 0.3 2.0 0.0 0.2 1.9 0.0 3.6 VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 436.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.8;Enteroendocrine cells: 113.6;Intestinal goblet cells: 143.6;Paneth cells: 216.2;Proximal enterocytes: 558.5;Undifferentiated cells: 161.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 56.4;stomach cancer: 23.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in some" 97 "CACO-2: 762.5;Hep G2: 365.3;OE19: 321.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA 6800 "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002452: AB_564052, HPA006884: AB_1080566, HPA006885: AB_1080564" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.36e-1)" "unprognostic (3.03e-1)" "unprognostic (5.90e-2)" "unprognostic (2.44e-2)" "unprognostic (7.06e-2)" "unprognostic (4.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-1)" "unprognostic (2.58e-1)" "unprognostic (4.79e-2)" "unprognostic (4.65e-2)" 0.6 1.1 0.0 10.3 0.1 0.3 0.8 0.3 0.2 0.7 0.0 175.9 395.0 0.5 0.0 0.9 0.7 28.1 1.0 0.0 0.0 25.9 31.4 0.7 0.3 0.0 0.0 1.1 29.4 0.0 1.4 0.3 0.0 1.0 184.0 0.0 0.6 0.4 0.4 1.1 436.3 8.1 0.0 1.2 6.9 2.0 0.0 0.0 0.6 0.0 0.0 0.8 0.9 0.1 0.0 1.5 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 762.5 0.5 0.1 5.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.3 365.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.1 0.0 1.7 0.8 321.9 0.0 0.0 0.0 1.4 0.0 0.2 0.3 0.7 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 4.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.3 0.8 0.4 0.1 0.0 1.8 0.3 0.6 0.5 24.3 0.1 0.0 2.1 0.3 0.8 243.8 3.9 12.3 1.9 1.3 0.9 0.4 113.6 3.2 0.7 42.9 0.2 0.8 6.6 1.6 8.9 0.3 0.7 32.6 0.1 1.7 0.5 143.6 0.0 2.2 1.5 0.5 0.0 5.1 0.0 0.0 0.2 0.5 0.0 0.0 0.3 10.9 216.2 0.0 0.3 0.9 558.5 35.1 0.0 1.2 0.0 1.7 0.7 0.8 0.8 0.6 0.9 0.3 1.5 0.0 161.8 0.3 VPS33B FLJ14848 ENSG00000184056 "VPS33B late endosome and lysosome associated" Q9H267 15 90998673-91022603 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA040415 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA040415: AB_10795419" "unprognostic (7.49e-2)" "unprognostic (1.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.55e-2)" "unprognostic (3.06e-1)" "unprognostic (1.79e-2)" "unprognostic (2.97e-2)" "unprognostic (2.42e-2)" "unprognostic (1.30e-1)" "unprognostic (2.84e-3)" "unprognostic (2.78e-2)" "unprognostic (7.94e-2)" "unprognostic (3.70e-1)" "unprognostic (6.75e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-2)" "unprognostic (1.00e-2)" 5.7 5.4 5.9 5.1 7.2 2.8 6.1 6.3 7.6 6.6 6.7 6.7 5.8 6.3 7.0 6.8 8.1 4.7 3.8 6.6 7.1 5.9 4.3 5.6 6.9 6.3 6.3 6.8 6.9 8.1 5.3 6.8 6.4 6.6 6.4 5.8 6.7 6.7 4.1 11.0 6.9 6.2 6.3 6.9 7.9 6.1 7.2 5.4 5.5 4.3 6.5 6.1 6.4 7.7 5.6 16.4 3.4 6.0 8.9 15.1 17.7 6.8 12.7 10.7 10.9 7.0 11.0 7.1 9.4 11.9 9.6 10.0 4.7 10.3 5.6 3.8 4.9 7.7 6.6 10.3 10.9 9.6 10.3 17.0 10.7 8.0 9.5 9.3 15.2 8.6 12.6 1.7 7.9 11.9 6.5 6.8 8.3 14.8 5.8 4.9 8.9 8.7 12.2 12.3 5.2 9.6 10.0 7.9 17.5 8.1 8.1 12.6 10.4 7.0 7.8 5.0 5.2 3.6 12.9 2.7 14.7 9.3 6.4 12.5 7.1 12.1 7.7 11.8 8.9 5.6 6.8 6.9 9.5 7.8 7.8 11.0 3.2 7.9 13.4 4.7 5.9 6.4 5.9 7.2 6.3 7.6 6.6 7.1 6.3 6.3 6.4 6.3 7.2 7.7 2.2 0.0 7.3 5.5 5.3 2.2 3.0 3.5 1.8 9.2 2.6 1.8 4.8 2.8 4.4 3.7 2.1 16.8 5.0 6.9 5.9 9.0 3.1 3.0 2.7 4.7 2.4 5.7 11.4 9.4 10.8 2.9 7.7 2.9 8.2 6.7 5.7 4.9 8.0 8.4 11.3 5.1 4.1 6.0 4.1 4.0 3.7 4.5 8.8 3.7 7.7 6.3 3.1 7.5 9.7 9.3 5.0 5.3 4.9 4.1 7.9 4.3 7.9 7.0 6.6 2.7 3.5 11.0 8.2 2.3 2.6 12.3 5.0 3.6 4.3 3.0 VPS37C FLJ20847 ENSG00000167987 "VPS37C subunit of ESCRT-I" A5D8V6 11 61130257-61161615 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 1.4;eosinophil: 1.7;intermediate monocyte: 2.6;myeloid DC: 1.0;neutrophil: 3.8;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 5 "dendritic cells: 1.0;granulocytes: 3.8;monocytes: 2.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043348 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA043348: AB_10794658" "unprognostic (1.97e-1)" "unprognostic (1.35e-1)" "unprognostic (2.50e-1)" "unprognostic (7.95e-3)" "unprognostic (3.38e-1)" "unprognostic (9.01e-2)" "prognostic unfavorable (5.85e-5)" "unprognostic (7.42e-2)" "unprognostic (1.14e-1)" "unprognostic (3.00e-1)" "unprognostic (3.41e-2)" "unprognostic (3.17e-2)" "prognostic favorable (2.37e-7)" "unprognostic (1.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.85e-1)" "unprognostic (7.05e-2)" 14.1 13.8 11.5 13.2 10.9 10.3 14.0 10.0 12.2 14.3 11.9 17.7 17.1 15.9 5.2 22.0 12.5 11.2 15.8 12.6 9.9 16.8 10.7 14.5 8.1 11.9 11.6 14.1 24.1 11.9 20.1 14.1 10.5 20.9 10.5 22.7 23.3 14.6 23.6 22.2 15.5 14.5 9.6 13.3 27.7 15.3 12.0 6.2 12.1 11.8 10.0 18.3 15.9 11.4 33.8 13.1 16.7 16.1 8.0 16.6 37.2 16.4 44.0 23.9 16.2 15.7 15.6 8.8 22.5 22.5 19.7 18.5 15.2 17.3 12.3 19.2 11.4 11.2 9.0 17.8 25.7 9.0 13.7 15.0 26.3 20.6 25.7 14.3 15.8 6.0 29.6 14.6 16.4 41.1 2.0 13.7 20.6 14.7 18.8 3.1 7.2 21.4 18.9 17.2 10.3 25.1 16.4 52.2 28.8 14.0 49.5 22.2 12.1 23.9 17.2 24.4 20.8 6.9 10.0 7.2 21.6 11.1 16.5 0.4 1.4 1.7 0.3 2.6 0.4 0.5 0.2 0.4 1.0 0.5 0.3 0.1 3.8 0.2 2.4 0.1 0.2 0.7 11.5 10.9 10.0 12.2 12.6 9.9 11.9 11.6 10.5 9.6 12.0 11.4 6.3 16.0 6.0 5.9 4.1 12.5 14.3 9.4 10.2 5.8 14.9 9.3 7.5 12.8 10.0 12.9 10.4 30.6 1.2 15.6 11.7 17.4 8.9 5.0 4.0 11.2 16.3 4.2 8.9 19.8 20.9 10.6 13.7 6.8 0.0 5.1 7.1 6.7 17.3 25.2 7.1 18.3 8.2 13.7 11.4 6.5 7.8 13.9 7.2 13.1 12.3 11.5 2.1 4.5 8.3 21.7 11.3 13.5 2.2 17.7 19.0 7.2 12.2 41.7 0.0 6.7 9.2 12.9 16.7 8.4 19.9 35.2 2.9 7.4 10.6 14.5 VPS45 "h-vps45, H1, VPS45A, VPS45B" ENSG00000136631 "Vacuolar protein sorting 45 homolog" Q9NRW7 1 150067279-150145329 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 202.8;Late spermatids: 267.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027425, HPA027441" Uncertain Approved Microtubules NA NA "Cluster 44: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" Microtubules "HPA027425: AB_10599415, HPA027441: AB_10602284" "unprognostic (1.57e-1)" "unprognostic (2.75e-1)" "unprognostic (2.03e-1)" "unprognostic (5.51e-2)" "unprognostic (1.56e-2)" "unprognostic (8.36e-3)" "prognostic unfavorable (6.57e-6)" "unprognostic (4.76e-2)" "unprognostic (2.94e-2)" "unprognostic (2.65e-3)" "unprognostic (2.52e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.49e-2)" "unprognostic (1.58e-1)" "unprognostic (1.72e-1)" "unprognostic (2.32e-2)" 19.1 26.8 32.3 12.0 34.6 6.6 17.8 40.2 43.0 20.1 27.7 22.0 12.6 18.7 22.5 16.7 16.1 13.7 38.6 34.0 33.2 21.1 12.5 15.4 13.5 30.6 31.4 14.0 11.1 26.4 19.1 17.3 31.5 18.8 17.2 29.2 14.3 20.1 19.3 16.5 15.3 25.2 31.5 16.2 17.4 11.0 32.9 17.0 19.8 16.6 15.3 18.5 15.9 32.8 31.5 24.3 40.9 27.0 37.1 29.4 19.0 44.7 23.7 45.3 37.4 17.7 26.1 19.3 26.5 37.0 19.9 26.0 42.4 27.0 49.0 38.7 31.1 24.6 33.5 16.8 24.7 17.6 30.2 25.8 24.8 43.5 22.8 29.7 37.1 38.6 34.4 28.3 40.0 53.5 34.7 17.5 28.4 28.7 38.4 23.7 41.9 27.4 31.2 30.0 28.5 59.7 34.9 29.8 46.9 46.2 48.9 45.6 32.6 20.8 25.1 18.7 31.3 21.3 49.4 18.9 30.9 24.4 30.2 23.6 26.6 4.7 16.0 28.0 15.0 15.6 13.6 15.1 25.9 12.8 13.2 13.9 2.5 14.1 19.9 14.6 16.8 18.4 32.3 34.6 40.2 43.0 34.0 33.2 30.6 31.4 31.5 31.5 32.9 32.8 9.4 12.8 14.0 85.8 11.9 7.4 8.2 12.7 13.1 20.9 11.0 10.2 44.0 8.6 11.0 16.5 18.8 20.9 12.5 8.3 7.9 12.3 202.8 9.7 14.2 10.4 7.8 4.6 79.4 7.2 9.5 14.7 12.8 10.1 6.3 24.6 12.1 7.2 19.0 30.3 90.2 8.1 14.2 18.0 8.6 267.9 21.5 13.6 10.6 45.9 19.7 17.9 6.2 92.5 59.5 11.4 11.6 14.7 8.4 6.4 13.6 9.2 11.5 23.8 32.9 7.3 17.1 18.1 15.1 11.6 7.7 14.8 11.2 21.2 9.7 7.9 VPS51 "ANG2, ANG3, C11orf2, C11orf3, FFR" ENSG00000149823 "VPS51 subunit of GARP complex" Q9UID3 11 65089324-65111862 "Disease related genes, Predicted intracellular proteins" "Lipid transport, Protein transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039650, HPA061447" Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 50: Non-specific - Ribosome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" Nucleoli "HPA039650: AB_10673147, HPA061447: AB_2684521" "unprognostic (2.36e-2)" "unprognostic (7.58e-2)" "unprognostic (8.35e-2)" "unprognostic (1.56e-1)" "unprognostic (2.11e-2)" "unprognostic (1.64e-1)" "unprognostic (9.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "prognostic favorable (2.41e-9)" "unprognostic (7.77e-3)" "unprognostic (4.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.18e-1)" 48.5 37.8 19.0 34.9 23.1 60.9 46.6 22.0 30.7 45.6 20.4 55.4 52.9 54.4 7.3 42.5 46.1 20.3 45.3 22.5 15.5 33.7 36.2 34.2 48.6 18.5 18.6 83.8 120.3 37.4 28.6 22.2 20.2 38.1 25.1 20.3 65.5 27.7 84.2 71.2 49.7 22.7 14.3 40.9 70.3 28.4 17.2 46.7 39.7 42.9 32.5 45.2 38.1 21.5 71.8 74.5 35.7 44.4 15.5 38.5 72.1 27.5 53.2 52.6 38.8 55.2 88.7 118.0 76.1 51.4 27.3 60.0 37.9 59.3 19.2 69.6 62.1 72.5 72.6 55.1 51.3 77.1 65.0 66.8 39.9 39.0 32.1 41.6 58.4 55.0 73.6 82.9 21.7 95.1 105.8 83.0 59.8 30.7 61.5 67.5 17.5 150.7 36.2 76.2 61.5 87.8 20.7 110.9 71.8 21.0 93.7 39.1 48.1 35.2 32.0 45.4 39.7 115.7 92.2 68.9 39.9 28.0 26.3 10.6 15.0 15.4 17.9 15.8 21.2 22.4 25.2 27.1 22.1 21.2 23.3 20.7 8.0 30.6 16.0 19.1 17.7 18.3 19.0 23.1 22.0 30.7 22.5 15.5 18.5 18.6 20.2 14.3 17.2 21.5 49.8 19.2 47.7 18.9 77.3 49.1 66.3 46.0 58.6 64.7 76.5 67.8 5.8 44.3 27.8 31.3 29.2 78.4 73.7 156.5 62.6 49.2 77.5 25.6 35.0 46.5 95.8 50.5 21.8 120.5 79.4 38.8 45.9 34.4 37.5 47.3 55.3 52.5 45.5 67.3 24.1 110.0 32.6 54.0 30.6 222.4 53.4 36.1 49.8 15.9 71.3 65.9 89.6 21.6 28.0 51.2 144.4 54.5 66.4 45.1 158.7 75.9 16.1 52.5 26.3 49.3 44.4 40.3 31.4 52.3 54.8 115.3 64.0 61.5 170.5 51.0 VSIG10L2 ENSG00000283703 "V-set and immunoglobulin domain containing 10 like 2" P0DP72 11 125946056-125958647 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "skin 1: 18.6" "Group enriched" "Detected in some" 4 "Breast glandular cells: 11.9;Breast myoepithelial cells: 6.7" "Region enhanced" "Detected in single" "cerebellum: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 35: Glandular cells - Unknown function" 0.2 0.0 0.1 0.0 0.2 0.0 1.8 3.2 0.8 0.8 0.0 0.0 0.0 0.3 0.0 0.8 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 18.6 0.0 0.7 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.2 0.8 0.3 0.1 0.1 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 6.7 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.1 0.1 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 VSNL1 "HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1" ENSG00000163032 "Visinin like 1" P62760 2 17539126-17657018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 663.3" "Group enriched" "Detected in many" 4 "Excitatory neurons: 442.7;Inhibitory neurons: 243.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 663.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 125.9;Hep G2: 124.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053808: AB_2682270" "unprognostic (1.04e-1)" "unprognostic (7.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (6.90e-4)" "unprognostic (4.90e-2)" "unprognostic (5.48e-2)" "unprognostic (2.81e-2)" "unprognostic (4.66e-2)" "unprognostic (2.99e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-1)" "unprognostic (5.14e-4)" "unprognostic (3.26e-2)" "unprognostic (1.23e-1)" "unprognostic (6.19e-3)" "unprognostic (1.51e-2)" 0.8 27.5 100.4 1.4 143.0 0.1 6.2 12.9 663.3 13.5 0.0 4.6 0.2 1.1 0.0 47.9 2.0 0.2 39.7 105.8 12.3 1.9 20.8 2.9 0.1 21.6 0.0 3.6 1.2 0.2 2.7 5.4 19.7 3.9 5.4 18.6 9.7 0.8 1.3 13.8 0.3 1.1 0.0 0.3 1.4 0.8 4.3 1.1 0.8 2.9 7.3 1.5 26.3 188.8 0.7 0.1 1.4 21.2 2.4 3.0 0.1 0.0 0.0 0.0 0.6 0.3 13.6 0.0 0.0 0.0 0.0 125.9 0.8 4.0 0.0 0.0 0.5 0.0 0.1 124.4 0.0 0.0 0.3 0.9 6.0 0.0 2.9 0.1 0.0 0.0 0.1 0.6 1.6 0.0 0.0 0.1 21.0 6.7 0.0 0.1 0.1 0.0 0.0 0.4 9.3 8.5 0.0 0.0 0.0 4.9 0.0 0.1 0.0 4.2 0.0 0.0 2.4 0.1 0.0 0.0 3.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 143.0 12.9 663.3 105.8 12.3 21.6 0.0 19.7 0.0 4.3 188.8 0.1 0.0 0.5 41.1 0.0 18.2 29.8 54.3 59.2 8.8 4.9 19.7 30.8 4.3 18.0 0.0 0.0 0.3 0.1 2.2 1.9 0.1 5.1 0.0 0.1 1.1 1.2 0.0 442.7 0.2 0.2 5.9 0.0 0.1 0.0 0.1 0.0 17.8 0.6 3.3 243.2 7.1 18.3 0.3 0.8 6.5 0.6 0.5 3.6 54.4 0.6 3.7 0.0 36.7 42.9 0.2 1.0 0.0 0.0 15.0 0.0 4.0 0.8 14.7 0.0 0.2 1.3 1.7 0.9 85.5 20.2 0.4 0.8 1.8 5.6 14.2 VWA5B1 FLJ32784 ENSG00000158816 "Von Willebrand factor A domain containing 5B1" Q5TIE3 1 20290919-20354894 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;choroid plexus: 19.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 10.9;Inhibitory neurons: 1.8;Late spermatids: 9.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "SCLC-21H: 1.2" "Low region specificity" "Detected in many" "HPA027496, HPA028405, HPA064829" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Secreted in male reproductive system" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "Plasma membrane, Cytosol" "HPA027496: AB_10599853, HPA028405: AB_10600992, HPA064829: AB_2685363" "unprognostic (2.34e-1)" "unprognostic (2.91e-1)" "unprognostic (7.78e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.86e-2)" "unprognostic (4.39e-2)" "unprognostic (1.73e-1)" "unprognostic (5.41e-4)" "unprognostic (7.43e-4)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" 0.0 0.4 0.8 0.1 0.9 0.0 0.0 0.1 0.1 0.0 19.1 0.0 0.0 0.0 1.3 0.0 0.3 0.2 0.0 1.1 2.9 1.3 0.0 0.1 0.1 3.7 6.3 0.0 0.0 1.1 2.9 0.1 5.1 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 3.0 0.0 0.2 0.4 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.1 0.1 1.1 2.9 3.7 6.3 5.1 1.5 3.0 0.7 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 WAPL "FOE, KIAA0261, WAPAL" ENSG00000062650 "WAPL cohesin release factor" Q7Z5K2 10 86435256-86521792 "Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037874, HPA037875, HPA066141" Enhanced Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA037874: AB_10697086, HPA037875: AB_10672396, HPA066141: " "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (3.03e-2)" "unprognostic (2.91e-2)" "unprognostic (6.63e-2)" "unprognostic (3.51e-1)" "unprognostic (3.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.25e-1)" "unprognostic (5.78e-2)" "unprognostic (5.56e-2)" "unprognostic (7.61e-2)" "unprognostic (1.14e-1)" "unprognostic (1.88e-1)" "unprognostic (4.56e-1)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" 15.4 13.2 8.4 19.6 9.9 27.1 16.6 11.9 9.2 12.8 7.8 15.4 15.2 14.8 8.7 15.9 11.7 13.1 10.3 7.5 8.3 16.8 22.6 16.5 25.0 8.2 8.5 13.7 14.4 16.9 4.9 18.4 8.3 13.0 15.2 36.0 11.2 11.7 20.9 17.9 16.0 14.8 8.9 19.0 16.5 35.1 9.0 33.7 17.9 22.5 27.7 17.9 9.2 10.4 42.6 19.6 33.5 44.4 26.1 27.6 29.6 36.4 44.2 30.3 32.4 42.9 36.6 64.3 24.1 32.5 26.7 39.1 38.3 31.3 46.3 42.1 25.3 38.9 30.9 47.4 29.7 79.8 43.1 21.9 35.7 38.9 64.9 34.5 34.6 36.8 41.7 37.6 35.2 36.3 49.9 29.6 29.9 26.4 19.5 35.2 27.1 25.6 26.3 37.2 13.1 25.2 32.3 21.4 40.9 33.2 47.1 41.9 33.5 29.1 34.4 25.8 48.6 36.8 54.9 66.9 26.7 55.8 20.9 15.0 3.5 7.7 3.4 4.1 4.9 3.9 4.5 4.7 4.8 4.0 5.1 4.0 5.5 3.2 7.4 3.6 6.1 2.4 8.4 9.9 11.9 9.2 7.5 8.3 8.2 8.5 8.3 8.9 9.0 10.4 38.3 83.3 54.8 0.0 48.3 0.0 57.4 0.0 35.3 49.1 41.3 27.9 0.0 20.0 21.1 16.5 20.9 42.8 62.4 17.4 21.5 60.8 86.8 36.7 44.4 33.9 18.2 94.1 0.0 52.5 28.3 30.0 37.8 52.2 25.2 40.3 32.5 47.6 40.4 55.5 0.0 21.5 0.0 56.5 0.0 42.0 32.0 58.3 0.0 0.0 81.0 48.7 55.6 0.0 0.0 52.1 27.5 32.4 50.5 56.6 25.0 35.5 13.8 113.4 65.7 70.3 33.6 153.4 90.2 48.4 0.0 76.1 51.4 35.2 24.8 74.1 WDHD1 "AND-1, CHTF4, CTF4" ENSG00000198554 "WD repeat and HMG-box DNA binding protein 1" O75717 14 54938949-55027105 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 15.5;Spermatocytes: 15.0;Spermatogonia: 19.3" "Cancer enhanced" "Detected in all" "testis cancer: 23.5" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000632, HPA001122" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA000632: , HPA001122: AB_1080589" "unprognostic (1.88e-1)" "unprognostic (1.21e-1)" "unprognostic (1.98e-2)" "unprognostic (2.25e-3)" "unprognostic (1.20e-1)" "unprognostic (6.85e-3)" "unprognostic (2.33e-4)" "unprognostic (5.52e-3)" "unprognostic (7.28e-3)" "unprognostic (8.05e-3)" "prognostic unfavorable (9.24e-4)" "unprognostic (5.11e-2)" "unprognostic (2.67e-4)" "unprognostic (8.31e-3)" "unprognostic (1.50e-1)" "unprognostic (3.49e-2)" "unprognostic (2.36e-2)" 1.3 0.8 0.5 3.8 1.0 7.2 2.2 0.9 0.9 1.2 0.1 2.8 1.8 2.1 0.6 2.4 1.6 1.3 0.9 0.7 0.2 1.1 1.2 1.3 5.5 0.2 0.2 1.4 0.9 1.5 0.3 2.8 0.2 1.0 4.0 1.8 0.7 0.8 0.6 2.0 1.7 2.6 0.3 1.7 1.6 5.3 0.4 8.0 0.9 0.8 6.7 1.7 1.1 0.9 39.6 24.7 48.4 21.4 4.6 11.2 28.1 37.5 16.1 29.6 36.0 16.6 25.9 44.9 18.6 10.8 21.4 32.8 72.9 21.5 61.7 30.0 12.7 29.8 23.7 16.2 1.9 56.7 21.8 5.9 3.8 36.6 14.3 7.1 19.6 28.8 37.8 22.0 28.7 21.7 53.5 11.1 38.6 21.1 25.7 49.5 69.7 17.3 8.4 26.0 28.1 19.8 39.8 10.0 12.8 35.1 26.8 11.3 12.8 37.3 43.9 27.5 32.1 6.5 14.4 58.8 17.1 27.4 30.0 1.7 0.3 0.6 0.9 0.2 1.2 1.2 1.0 1.3 0.5 1.8 1.3 1.8 0.4 2.0 0.4 0.7 1.6 0.6 0.5 1.0 0.9 0.9 0.7 0.2 0.2 0.2 0.2 0.3 0.4 0.9 2.3 0.0 2.0 3.9 5.1 3.8 2.2 3.5 3.4 2.9 1.8 1.9 1.7 0.0 4.0 3.7 0.0 8.7 3.6 1.8 0.0 1.8 0.8 1.9 3.1 2.0 0.0 15.5 10.3 1.0 8.4 3.4 2.6 2.5 0.0 12.4 0.7 0.9 4.1 3.3 6.5 2.4 6.1 2.1 1.2 1.1 0.0 2.4 1.8 5.6 1.4 1.4 2.1 4.5 10.1 1.1 0.3 3.0 7.8 0.6 0.5 6.2 3.5 3.1 0.0 2.4 3.0 15.0 19.3 6.1 2.4 2.6 3.6 2.8 5.2 1.7 WDR20 "DMR, FLJ33659, MGC33177" ENSG00000140153 "WD repeat domain 20" Q8TBZ3 14 102139503-102224847 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 241.9;Late spermatids: 250.6;Oligodendrocytes: 201.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" "unprognostic (5.59e-2)" "unprognostic (1.00e-1)" "unprognostic (8.45e-2)" "unprognostic (7.70e-2)" "unprognostic (5.48e-2)" "unprognostic (5.14e-2)" "unprognostic (2.43e-2)" "unprognostic (3.96e-2)" "unprognostic (1.78e-1)" "unprognostic (5.04e-2)" "unprognostic (1.19e-2)" "unprognostic (3.26e-2)" "prognostic favorable (3.26e-9)" "unprognostic (6.62e-2)" "unprognostic (2.01e-1)" "unprognostic (2.68e-2)" "unprognostic (1.41e-2)" 12.2 17.0 11.2 9.4 16.3 10.7 11.7 18.7 15.6 11.5 13.3 10.8 16.0 10.3 12.0 13.5 10.7 8.9 10.0 12.3 15.0 12.5 10.9 8.8 11.5 16.5 14.0 12.3 12.3 11.9 10.5 9.9 16.1 10.2 10.5 29.9 11.4 7.4 11.8 16.0 13.1 9.1 11.6 10.4 10.6 23.9 14.3 12.3 14.1 13.0 10.8 10.4 12.1 28.7 16.2 20.6 14.6 13.0 16.4 14.3 19.2 19.8 16.4 21.9 17.7 17.6 15.2 17.7 12.9 18.6 11.9 19.3 21.6 17.8 27.7 25.0 9.8 9.3 14.8 19.4 12.6 14.4 16.1 11.2 16.7 15.8 15.5 22.0 15.4 14.2 12.3 18.6 23.9 37.2 13.3 21.8 13.0 22.3 22.7 13.3 14.5 11.9 31.8 25.4 18.4 20.8 17.3 22.2 13.9 16.2 24.1 13.8 17.0 20.3 9.3 32.2 18.7 14.6 21.9 18.8 18.5 11.7 22.2 28.5 20.7 37.7 25.8 21.2 27.0 27.6 28.4 24.2 21.0 19.9 28.9 27.4 40.2 30.4 21.4 12.4 33.6 21.0 11.2 16.3 18.7 15.6 12.3 15.0 16.5 14.0 16.1 11.6 14.3 28.7 17.5 9.6 14.5 48.6 21.0 25.1 15.4 19.6 16.5 20.5 16.3 12.7 10.4 10.0 16.7 11.0 16.7 25.6 22.8 19.6 21.5 17.9 241.9 20.1 14.5 12.9 11.4 25.0 43.3 17.3 19.4 15.6 14.3 21.1 22.9 15.0 15.0 12.7 13.4 33.7 42.9 12.8 18.3 10.4 13.8 250.6 13.1 12.9 21.4 48.7 15.6 23.8 22.6 68.9 201.5 18.9 17.6 15.1 17.4 19.0 27.5 25.1 15.6 54.6 13.1 18.6 17.4 43.0 25.3 16.4 27.4 34.9 22.3 8.7 12.1 21.7 WDR47 KIAA0893 ENSG00000085433 "WD repeat domain 47" O94967 1 108970214-109042113 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 93.6;Suprabasal keratinocytes: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027287, HPA027289" Approved Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "Actin filaments" Nucleoplasm "HPA027287: AB_10599416, HPA027289: AB_10601862" "unprognostic (8.55e-2)" "unprognostic (3.36e-2)" "unprognostic (7.51e-2)" "unprognostic (2.44e-1)" "unprognostic (4.90e-1)" "prognostic favorable (9.86e-4)" "unprognostic (4.05e-3)" "unprognostic (2.83e-2)" "unprognostic (2.87e-1)" "unprognostic (3.67e-2)" "unprognostic (2.71e-2)" "unprognostic (1.93e-1)" "unprognostic (8.39e-3)" "unprognostic (7.90e-3)" "unprognostic (9.23e-2)" "unprognostic (2.73e-2)" "unprognostic (8.09e-2)" 7.8 7.1 22.6 5.5 26.6 12.2 6.3 14.1 27.3 8.8 1.5 8.0 3.7 9.3 5.7 14.4 8.5 7.3 8.1 27.7 17.9 7.6 3.5 7.0 5.6 13.4 11.0 7.5 5.9 9.2 5.3 6.5 14.6 7.3 5.3 37.0 5.8 7.0 17.0 22.9 4.5 10.2 10.9 5.7 6.0 22.7 16.7 7.7 6.2 15.3 7.5 7.5 8.9 19.5 15.6 4.7 8.8 10.9 17.0 14.8 4.7 17.4 10.7 11.4 12.7 4.6 2.3 7.0 9.0 16.7 8.4 17.1 12.5 7.6 15.0 13.1 7.0 5.8 9.9 5.3 9.7 9.2 8.3 9.2 12.4 17.9 8.5 13.8 13.7 8.1 3.5 9.5 19.4 9.3 8.9 7.2 3.7 5.0 9.1 12.5 22.3 3.9 19.0 13.3 15.3 14.0 15.2 8.1 12.5 9.4 3.7 9.3 23.5 15.1 7.0 26.7 14.5 6.1 5.4 5.5 17.6 9.0 23.0 18.0 5.4 7.1 3.3 5.7 3.1 2.4 3.1 3.5 5.8 3.4 2.8 2.5 22.0 2.7 5.9 6.3 5.5 2.6 22.6 26.6 14.1 27.3 27.7 17.9 13.4 11.0 14.6 10.9 16.7 19.5 16.5 12.8 6.5 33.3 13.8 93.6 5.1 7.7 62.0 15.3 11.1 12.6 18.9 10.0 8.0 7.3 45.9 2.4 25.1 2.7 5.9 3.5 33.2 20.5 9.3 12.1 3.0 1.7 46.2 0.9 2.1 10.7 8.2 10.4 2.5 5.6 7.1 2.0 4.4 11.8 39.1 1.0 4.1 5.5 28.4 41.4 8.4 13.9 24.9 19.7 6.3 13.2 8.2 15.1 26.5 3.9 0.9 15.1 14.9 2.4 2.4 5.5 18.9 32.3 6.6 13.5 16.5 32.2 28.9 52.1 104.4 4.9 18.9 3.3 2.1 4.1 WDR72 FLJ38736 ENSG00000166415 "WD repeat domain 72" Q3MJ13 15 53513741-53762878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 105.7;liver: 33.1;thyroid gland: 57.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 12.8;Collecting duct cells: 22.0;Glandular and luminal cells: 13.2;Hepatocytes: 44.3;Proximal tubular cells: 93.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 9.9;OE19: 18.3;RPMI-8226: 17.5;RPTEC TERT1: 10.1;SuSa: 15.2;U-266/70: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048212, HPA057410, HPA059819" Uncertain Approved Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA048212: AB_2680315, HPA057410: AB_2683430, HPA059819: AB_2684133" "unprognostic (6.39e-4)" "unprognostic (1.41e-1)" "unprognostic (3.19e-2)" "unprognostic (1.79e-2)" "unprognostic (2.63e-2)" "unprognostic (3.37e-2)" "unprognostic (5.54e-2)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.26e-1)" "unprognostic (2.78e-2)" "unprognostic (1.09e-2)" "prognostic favorable (3.33e-16)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (7.67e-2)" 0.1 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.1 7.2 0.0 0.6 2.6 1.4 0.5 0.4 2.6 3.9 0.1 0.0 0.1 105.7 33.1 0.8 0.1 0.1 0.4 0.2 3.5 1.8 0.3 0.1 0.1 0.1 0.8 0.7 18.4 0.6 0.0 2.0 0.9 0.0 0.0 0.1 1.1 0.5 0.1 0.0 57.9 0.0 0.0 1.7 0.0 0.3 0.0 9.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 3.2 0.1 6.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.9 18.3 0.1 0.0 0.1 17.5 10.1 3.5 1.9 0.0 0.0 0.1 0.0 15.2 2.4 0.0 0.1 0.3 0.5 0.0 0.1 7.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 6.4 3.6 0.0 0.5 0.1 1.1 0.0 0.6 0.5 0.0 0.1 0.6 12.8 0.0 22.0 0.0 0.6 0.0 0.2 9.8 3.2 1.2 4.9 1.0 0.1 0.0 0.0 0.4 0.5 2.1 0.2 0.0 13.2 0.0 0.0 0.0 44.3 0.1 3.3 0.5 0.0 0.0 0.6 0.0 0.3 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 93.2 0.1 0.1 0.0 0.0 0.1 1.0 1.6 0.9 0.4 0.1 0.7 0.0 0.3 6.4 WDR76 FLJ12973 ENSG00000092470 "WD repeat domain 76" Q9H967 15 43826980-43868412 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.1;lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.3;Spermatocytes: 23.5;Spermatogonia: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039804, HPA040626" Uncertain Approved "Nucleoli fibrillar center,Nuclear bodies" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear bodies" "Nucleoli fibrillar center" "HPA039804: AB_10795297, HPA040626: AB_10795527" "unprognostic (2.26e-1)" "unprognostic (7.56e-3)" "unprognostic (7.05e-2)" "unprognostic (1.88e-1)" "unprognostic (5.85e-2)" "unprognostic (3.12e-2)" "prognostic unfavorable (6.98e-4)" "prognostic unfavorable (8.02e-5)" "unprognostic (4.24e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.91e-2)" "prognostic unfavorable (1.35e-8)" "unprognostic (7.71e-2)" "unprognostic (9.42e-2)" "unprognostic (4.02e-2)" "unprognostic (3.28e-2)" 2.6 1.2 1.0 8.4 1.1 19.1 3.5 4.8 1.7 3.0 0.8 4.8 3.2 3.3 0.9 4.5 1.7 1.9 1.1 0.7 1.1 1.5 2.2 2.4 19.8 1.3 1.1 2.2 3.1 2.7 1.1 3.9 1.3 1.9 6.0 6.3 2.4 2.0 0.8 4.1 3.3 3.9 1.0 3.6 2.9 5.3 1.3 19.5 2.5 1.3 21.3 2.8 2.8 1.2 35.1 17.5 40.7 31.3 4.5 10.7 11.1 57.3 33.9 61.5 76.8 22.1 17.8 51.4 24.8 26.9 31.0 49.4 42.4 20.5 53.1 80.4 25.2 63.3 52.1 7.3 2.5 65.0 27.0 3.4 3.3 33.8 7.7 8.9 19.9 54.7 48.6 86.9 42.6 12.2 63.4 15.4 14.6 11.0 18.1 66.9 70.1 32.4 11.4 35.5 31.3 30.9 36.1 22.5 7.0 12.6 35.0 31.0 9.1 56.3 26.5 63.5 58.9 42.7 114.6 129.1 40.4 56.7 31.5 0.0 0.6 0.3 3.8 0.5 4.1 1.8 4.6 3.4 1.0 2.2 3.8 2.9 0.0 4.8 0.2 1.2 6.6 2.0 1.0 1.1 4.8 1.7 0.7 1.1 1.3 1.1 1.3 1.0 1.3 1.2 4.1 3.2 1.3 2.6 8.2 7.4 3.2 2.4 4.6 3.7 3.7 2.8 1.2 1.5 2.3 1.8 10.4 12.8 6.2 3.5 1.9 2.9 1.7 1.8 3.9 4.8 0.0 35.3 2.5 4.2 13.0 3.9 4.6 3.3 5.7 12.2 2.9 0.9 8.9 1.7 3.3 3.7 0.0 3.5 5.3 0.9 1.8 3.9 3.6 2.8 3.3 8.0 10.3 0.5 1.9 1.1 3.1 2.2 16.1 1.5 1.4 0.9 0.4 16.2 6.6 5.8 5.7 23.5 35.9 7.4 5.8 3.6 11.6 1.5 9.0 1.8 WFDC10B WAP12 ENSG00000182931 "WAP four-disulfide core domain 10B" Q8IUB3 20 45684653-45705019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 27.3;retina: 11.7" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Early spermatids: 5.5;Late spermatids: 10.1;Microglial cells: 3.7;Rod photoreceptor cells: 9.6;Spermatocytes: 4.8" "Cancer enhanced" "Detected in some" "lung cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "PC-3: 1.9" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "unprognostic (1.14e-1)" "unprognostic (2.31e-1)" "unprognostic (1.37e-4)" "unprognostic (1.60e-1)" "unprognostic (2.69e-1)" "unprognostic (4.81e-2)" "unprognostic (4.30e-3)" "unprognostic (5.64e-2)" "unprognostic (1.14e-2)" "unprognostic (3.36e-1)" "unprognostic (0.00e+0)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" "unprognostic (2.21e-2)" "unprognostic (3.17e-1)" 0.2 0.0 0.2 0.0 0.2 0.0 0.3 0.2 0.6 0.4 0.2 0.6 0.0 0.3 27.3 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.0 0.7 0.0 0.5 0.6 0.1 0.0 0.0 0.1 0.4 0.3 0.7 0.5 11.7 0.0 0.2 0.0 1.2 0.2 0.4 0.4 0.0 0.3 4.3 0.2 0.2 0.0 0.0 0.0 5.9 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.6 1.9 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.2 0.1 0.5 0.6 0.3 0.4 0.2 0.3 0.0 0.0 0.5 3.6 0.0 0.0 0.1 0.4 0.0 0.2 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.3 0.0 0.1 0.0 0.0 1.3 0.4 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.3 0.4 2.0 0.0 0.0 10.1 0.0 0.0 0.0 3.7 0.0 0.9 0.0 1.5 0.9 1.2 0.1 0.0 0.0 0.4 0.3 0.0 0.0 9.6 0.0 0.0 0.1 4.8 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.7 WFDC6 "C20orf171, dJ461P17.11, WAP6" ENSG00000243543 "WAP four-disulfide core domain 6" Q9BQY6 20 45534196-45539482 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "epididymis: 250.9" "Cell type enriched" "Detected in some" 4 "Respiratory ciliated cells: 34.2" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.9;testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "U-87 MG: 2.6" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.68e-3)" "unprognostic (2.21e-3)" "unprognostic (1.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.91e-2)" 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.4 1.0 0.0 0.0 0.0 0.2 250.9 0.1 7.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.5 0.1 0.0 0.0 0.0 0.0 37.6 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 6.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 34.2 0.0 0.0 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 599.7" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 2736.1" "Group enriched" "Detected in many" 5 "endometrial cancer: 16.9;lung cancer: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.2;LHCN-M2: 1.0;NTERA-2: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.96e-3)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (3.26e-3)" "unprognostic (9.66e-2)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (7.94e-2)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-5)" "unprognostic (3.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (7.24e-3)" 1.3 2.7 22.4 0.3 34.3 0.0 22.9 16.3 44.6 1.6 15.0 0.3 0.0 8.6 23.8 4.7 1.5 0.0 0.5 24.8 35.4 0.7 0.0 117.4 0.1 16.6 16.5 1.2 0.3 0.0 46.5 0.0 16.2 14.2 0.3 599.7 45.1 2.8 0.1 6.6 2.2 0.9 16.5 0.1 1.4 0.7 23.4 0.2 0.0 0.7 0.0 1.7 2.2 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 34.3 16.3 44.6 24.8 35.4 16.6 16.5 16.2 16.5 23.4 18.4 0.0 35.3 197.8 186.1 0.0 12.6 34.5 0.0 2.2 25.0 0.7 13.7 1.6 0.0 26.6 1.8 8.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 4.7 0.0 0.0 0.6 0.0 0.0 27.8 0.5 0.1 7.6 1.0 0.0 0.0 0.0 15.2 46.5 0.0 0.0 0.0 20.4 0.0 0.0 0.8 23.2 12.2 0.0 2736.1 0.0 1.5 0.9 0.0 0.0 0.4 0.2 25.5 0.0 1.2 34.2 80.8 0.0 1.8 1.5 2.5 2.0 0.4 10.5 0.0 1.2 0.0 0.0 0.8 WIPF3 "CR16, FLJ36931" ENSG00000122574 "WAS/WASL interacting protein family member 3" A6NGB9 7 29806486-29917066 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;ovary: 41.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.1;Granulosa cells: 149.4;Leydig cells: 50.7;Peritubular cells: 100.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 22.1;cerebral cortex: 49.9;hippocampal formation: 40.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.1;HEK 293: 4.1;K-562: 6.6;NTERA-2: 5.1;RPMI-8226: 11.3;SK-MEL-30: 4.5" "Region enhanced" "Detected in all" "hippocampal formation: 213.9" "Region enhanced" "Detected in all" "hippocampal formation: 156.3" "HPA041145, HPA041211" Uncertain Uncertain Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041145: AB_10795001, HPA041211: AB_10795003" "prognostic favorable (7.93e-4)" "unprognostic (1.35e-1)" "unprognostic (1.37e-3)" "unprognostic (2.12e-3)" "unprognostic (3.65e-3)" "unprognostic (1.53e-1)" "unprognostic (8.95e-3)" "unprognostic (4.53e-2)" "unprognostic (3.49e-1)" "unprognostic (1.19e-2)" "unprognostic (1.08e-2)" "unprognostic (7.49e-2)" "unprognostic (1.61e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-2)" "unprognostic (3.33e-2)" "unprognostic (1.41e-1)" 1.0 5.6 8.7 1.0 22.1 0.5 1.1 0.0 49.9 0.4 0.0 0.7 2.9 3.3 19.7 1.2 8.8 1.4 4.0 40.3 4.2 2.5 0.5 0.5 0.7 0.4 2.6 41.7 1.7 1.2 0.9 0.2 0.1 4.4 0.5 3.8 4.0 4.8 25.0 0.9 2.6 4.1 0.5 1.0 5.9 18.8 7.4 0.4 2.0 8.8 0.7 1.4 0.2 8.1 0.3 1.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 18.1 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.1 0.0 0.1 0.0 0.0 5.1 0.0 3.6 0.0 0.0 11.3 0.0 0.0 1.8 1.5 0.1 0.1 4.5 2.4 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.1 0.0 8.7 22.1 0.0 49.9 40.3 4.2 0.4 2.6 0.1 0.5 7.4 8.1 1.5 0.0 0.0 6.2 0.0 2.2 1.5 0.6 1.2 8.2 4.9 4.6 9.3 0.0 1.4 3.7 2.1 0.0 0.3 0.5 3.9 3.8 1.8 5.0 0.4 4.1 1.8 3.0 45.1 3.5 0.1 7.3 11.7 1.2 0.0 149.4 0.4 0.5 4.5 5.0 27.0 0.7 0.0 0.0 1.0 4.8 50.7 1.0 5.4 1.9 0.0 6.2 0.0 2.0 1.9 2.4 1.5 100.4 0.1 1.1 5.5 5.5 5.1 2.9 6.6 7.2 16.0 4.4 9.9 0.9 0.4 0.0 1.0 8.7 2.0 0.4 WIPI2 "ATG18B, ATG21, CGI-50, DKFZP434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984" ENSG00000157954 "WD repeat domain, phosphoinositide interacting 2" Q9Y4P8 7 5190196-5233840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 255.9;Spermatocytes: 233.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019852, HPA021488" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Nucleoplasm "HPA019852: AB_1846589, HPA021488: AB_1846591" "unprognostic (5.79e-2)" "unprognostic (1.47e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (7.69e-5)" "unprognostic (1.96e-3)" "unprognostic (9.27e-3)" "unprognostic (4.60e-3)" "unprognostic (4.96e-2)" "unprognostic (6.60e-2)" "unprognostic (4.23e-1)" "prognostic favorable (9.78e-4)" "unprognostic (1.20e-1)" "prognostic favorable (2.05e-6)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (7.41e-2)" "unprognostic (6.98e-2)" 31.1 30.9 38.8 22.9 40.7 47.0 30.8 35.2 41.8 27.3 37.1 33.9 24.7 32.1 26.3 35.8 29.0 23.2 38.0 42.8 38.6 32.2 35.7 26.4 30.2 36.3 39.1 28.2 37.1 38.2 30.6 32.8 38.7 28.7 20.2 19.1 43.5 28.2 41.3 47.1 26.7 26.8 37.0 29.6 33.6 53.8 38.7 36.8 27.4 45.0 29.2 27.1 30.0 39.8 67.5 42.1 40.4 69.4 60.7 63.3 62.0 58.7 66.9 61.2 64.2 41.2 60.9 47.7 43.9 73.8 76.0 48.2 41.2 47.8 47.4 24.9 64.1 32.7 39.7 45.8 59.9 51.8 34.4 66.9 56.4 69.7 38.3 60.9 86.3 64.3 94.2 41.9 56.2 69.9 39.6 90.0 84.3 35.9 61.1 64.3 57.7 79.5 40.4 32.3 50.3 75.4 43.0 72.8 52.4 67.3 44.8 97.2 69.2 38.9 80.9 65.6 44.4 75.0 75.2 54.7 63.4 59.3 58.8 0.4 4.7 13.6 4.4 6.0 2.8 5.7 5.8 8.0 4.2 6.2 7.5 4.7 9.1 2.6 4.2 6.4 9.0 2.2 38.8 40.7 35.2 41.8 42.8 38.6 36.3 39.1 38.7 37.0 38.7 39.8 40.2 38.5 31.5 16.3 51.6 54.9 39.5 13.9 39.3 71.5 49.4 50.5 37.0 42.9 17.6 18.4 62.6 89.4 62.7 42.6 72.4 43.0 195.8 50.0 38.1 37.9 39.5 125.0 19.7 41.8 96.6 43.1 34.7 48.0 31.1 54.8 54.7 60.4 69.1 47.1 19.6 42.6 18.3 61.4 44.8 255.9 42.6 55.9 44.4 20.6 64.5 89.5 44.3 13.6 23.5 55.6 37.0 56.1 67.7 97.7 48.7 80.6 26.4 52.8 52.6 39.7 39.4 233.0 117.3 49.8 71.0 150.8 46.8 44.1 43.0 69.8 WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.3;skin 1: 27.7" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 44.5;Early spermatids: 27.7;Late spermatids: 63.8;Suprabasal keratinocytes: 17.6" "Cancer enriched" "Detected in many" 6 "testis cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;U-698: 14.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA049893: " "unprognostic (1.84e-1)" "unprognostic (2.90e-2)" "unprognostic (2.35e-1)" "unprognostic (6.41e-4)" "unprognostic (4.73e-2)" "unprognostic (5.26e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (4.97e-2)" "unprognostic (2.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-8)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" 0.8 0.4 1.3 0.4 1.1 0.1 1.0 0.7 1.0 1.0 0.2 0.6 3.4 0.5 0.0 1.3 0.5 0.1 0.9 0.8 1.2 1.7 12.3 0.9 0.2 1.4 1.8 0.5 0.8 2.5 1.7 0.2 1.2 1.3 0.2 0.2 1.2 0.0 0.2 27.7 2.7 0.2 0.7 0.7 0.4 4.4 4.4 0.1 1.3 0.0 0.1 0.4 1.1 0.7 3.9 1.7 8.5 0.0 0.1 0.1 0.7 0.8 0.9 3.0 0.0 2.7 1.7 1.6 2.3 2.1 6.1 1.3 0.4 0.0 3.9 0.0 0.4 0.0 3.0 2.3 0.0 0.1 0.1 0.2 1.8 1.1 2.3 3.5 1.1 2.5 1.5 0.0 1.0 1.7 0.0 1.4 0.0 1.0 2.4 2.9 1.9 0.2 0.6 0.0 0.1 0.7 1.6 0.0 1.2 2.1 0.0 4.0 0.2 3.2 2.1 0.4 1.5 0.6 0.2 14.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 1.1 0.7 1.0 0.8 1.2 1.4 1.8 1.2 0.7 4.4 0.7 0.2 0.0 1.5 3.9 0.5 44.5 0.6 0.6 3.4 1.1 3.0 1.7 1.3 1.5 0.4 0.0 0.0 2.2 0.1 0.7 1.9 0.7 27.7 0.1 0.7 0.5 0.0 0.0 5.4 2.5 0.1 1.1 0.0 0.2 0.0 0.7 0.4 4.0 0.2 8.4 4.3 0.6 0.0 0.0 1.5 63.8 0.3 0.1 1.8 1.0 0.6 0.2 0.0 4.0 1.1 2.9 1.4 0.4 0.0 1.2 3.7 0.5 0.3 0.8 0.0 1.4 1.1 0.9 2.9 0.8 17.6 0.3 0.0 0.3 0.9 0.3 WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Basal keratinocytes: 3.4;Basal prostatic cells: 3.1;Basal squamous epithelial cells: 8.6;Syncytiotrophoblasts: 2.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HEK 293: 1.1;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 9: U-2 OS - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 1.3 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 3.4 3.1 1.2 8.6 0.0 0.0 0.1 1.9 0.0 0.9 1.8 0.0 2.0 0.0 0.4 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 1.0 2.9 0.0 0.0 0.1 0.5 WNT4 WNT-4 ENSG00000162552 "Wnt family member 4" P56705 1 22117313-22143969 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 40.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.1;Breast glandular cells: 19.9;Breast myoepithelial cells: 24.3;Endometrial stromal cells: 71.4;Enteroendocrine cells: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 8.5;SCLC-21H: 10.2;SK-BR-3: 8.6;T-47d: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011397 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA011397: AB_1858854" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (6.67e-3)" "unprognostic (1.75e-2)" "unprognostic (7.17e-2)" "unprognostic (4.30e-3)" "unprognostic (2.77e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.34e-4)" "unprognostic (2.14e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (4.21e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-2)" "unprognostic (9.49e-2)" 0.8 9.0 2.4 0.4 1.5 0.3 2.2 0.2 2.9 8.9 0.5 2.3 3.2 4.5 8.9 12.1 8.3 2.6 0.1 2.0 2.9 1.1 1.4 1.2 0.1 1.6 1.8 16.8 3.0 0.1 5.6 1.6 1.2 5.5 1.6 0.2 4.1 2.6 3.1 40.8 3.1 1.9 1.1 0.3 4.3 0.6 3.9 1.1 3.4 0.6 1.5 3.1 6.3 1.1 1.3 0.1 2.5 0.1 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.3 8.5 0.0 0.6 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 1.1 0.2 0.3 0.0 0.0 0.0 1.6 10.2 0.0 0.1 8.6 0.6 0.6 3.4 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.5 0.2 2.9 2.0 2.9 1.6 1.8 1.2 1.1 3.9 1.1 0.9 3.2 8.6 0.3 0.7 16.7 4.3 42.1 6.8 0.0 19.9 24.3 0.6 0.0 15.2 0.0 0.0 0.7 0.1 0.9 0.0 2.7 0.1 4.1 71.4 0.6 29.4 0.0 0.2 0.6 0.1 3.1 0.5 1.6 0.0 0.2 0.7 0.5 0.1 0.0 1.9 16.0 4.1 0.0 0.2 0.9 0.0 0.4 5.4 6.5 0.1 0.0 0.0 0.0 0.3 0.9 0.1 3.8 0.6 5.7 0.3 0.0 12.0 0.0 0.0 0.4 2.2 0.0 0.3 2.5 10.4 0.3 0.6 0.0 0.6 4.2 WNT7A Wnt-7a ENSG00000154764 "Wnt family member 7A" O00755 3 13816258-13880071 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;gallbladder: 2.3;placenta: 2.7" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 68.7;Extravillous trophoblasts: 147.5;Pancreatic endocrine cells: 98.8;Syncytiotrophoblasts: 185.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.2;ovarian cancer: 11.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory CD4 T-cell: 1.7;naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Cell line enhanced" "Detected in some" "BEWO: 59.8;EFO-21: 56.0;PC-3: 19.9;RPTEC TERT1: 100.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015719, CAB025894" Approved "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB025894: , HPA015719: AB_1858856" "unprognostic (1.26e-2)" "unprognostic (4.60e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.96e-5)" "unprognostic (3.02e-1)" "unprognostic (1.14e-3)" "unprognostic (2.49e-1)" "unprognostic (3.32e-4)" "unprognostic (2.20e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (7.89e-2)" "unprognostic (3.78e-2)" "unprognostic (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (3.74e-1)" "unprognostic (8.88e-3)" 0.0 0.0 3.6 0.1 3.1 0.1 0.0 1.0 3.7 0.2 0.3 0.0 0.0 1.1 0.2 0.4 0.1 2.3 0.0 2.4 2.1 0.2 0.0 2.0 0.2 5.1 1.9 0.0 0.1 0.0 0.0 2.7 2.5 0.1 0.0 0.0 0.0 0.3 0.0 0.9 0.0 0.0 3.4 1.3 0.0 1.3 2.5 0.0 0.0 0.0 0.1 0.3 0.1 2.8 8.6 0.0 0.8 0.0 0.0 0.0 59.8 0.0 0.0 0.0 0.0 0.0 7.6 0.0 56.0 0.0 0.1 11.2 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 1.7 100.3 0.9 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 3.6 3.1 1.0 3.7 2.4 2.1 5.1 1.9 2.5 3.4 2.5 2.8 0.0 12.8 0.0 8.5 0.0 5.9 2.8 2.6 0.0 0.0 0.0 0.0 0.7 8.6 1.4 0.0 0.0 68.7 0.0 0.0 0.0 13.8 17.3 14.5 0.4 0.6 0.0 0.0 4.0 9.1 147.5 0.4 0.0 17.9 0.0 0.0 0.0 0.0 7.4 0.0 2.4 0.0 0.0 0.0 0.0 5.6 0.0 0.1 0.0 1.0 0.0 0.0 0.0 4.5 0.3 98.8 0.0 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.2 6.0 2.3 0.0 1.3 185.7 1.5 0.0 0.0 6.0 WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.4;skin 1: 17.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.6;Basal prostatic cells: 26.4;Basal squamous epithelial cells: 42.1;Club cells: 23.9;Pancreatic endocrine cells: 43.3;Prostatic glandular cells: 26.2;Urothelial cells: 46.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 119.4;HeLa: 103.7;RPTEC TERT1: 41.4;SK-BR-3: 51.0;U-87 MG: 93.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.02e-3)" "unprognostic (7.83e-3)" "unprognostic (8.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "unprognostic (3.85e-3)" "unprognostic (1.69e-2)" "unprognostic (8.58e-4)" "unprognostic (1.90e-1)" "unprognostic (6.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" 0.0 0.0 4.6 0.0 3.4 0.0 1.1 1.8 5.1 3.5 0.4 0.0 0.0 0.1 0.1 12.4 1.2 2.9 0.0 4.9 4.5 6.3 0.1 3.1 0.0 2.7 2.3 0.0 0.5 0.1 0.5 0.4 4.3 4.4 0.0 0.0 2.2 1.9 0.0 17.9 0.0 0.0 1.7 0.0 0.0 0.3 5.4 0.7 0.3 0.0 1.0 9.1 8.3 1.9 23.2 119.4 0.3 0.0 0.0 0.0 15.2 0.4 1.3 0.0 0.0 0.5 15.5 0.1 3.7 0.2 1.3 25.8 0.9 15.1 0.0 0.1 1.0 0.0 103.7 0.6 0.0 0.0 0.1 0.0 10.2 0.1 3.0 0.4 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.1 9.7 22.4 0.0 0.0 1.3 41.4 33.9 4.3 0.0 10.3 51.0 0.0 0.2 8.5 13.6 0.0 2.1 1.8 0.0 1.0 0.0 0.0 0.0 93.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 3.4 1.8 5.1 4.9 4.5 2.7 2.3 4.3 1.7 5.4 1.9 0.3 6.4 15.6 3.9 0.5 33.6 26.4 16.3 42.1 0.5 4.0 0.6 1.6 8.6 23.9 12.9 4.2 3.5 0.1 0.1 0.0 5.9 0.3 1.7 0.4 0.7 0.0 0.0 0.3 0.5 0.3 1.7 0.0 4.3 2.5 0.2 0.4 0.1 0.1 0.0 1.2 0.0 0.0 0.0 3.7 0.2 0.3 0.3 0.0 1.0 1.0 0.2 0.0 7.5 0.1 43.3 0.0 0.4 1.5 26.2 0.0 0.1 13.8 1.1 0.0 0.8 1.9 0.2 1.8 21.0 20.5 0.7 0.5 0.0 0.0 46.6 WWC2 "BOMB, FLJ22029" ENSG00000151718 "WW and C2 domain containing 2" Q6AWC2 4 183099257-183320777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 262.8;Microglial cells: 129.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 84.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044005 Uncertain Approved Microtubules NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Microtubules "HPA044005: AB_10960552" "unprognostic (1.07e-1)" "prognostic unfavorable (8.61e-4)" "unprognostic (7.16e-4)" "unprognostic (1.70e-1)" "unprognostic (2.00e-2)" "unprognostic (4.48e-3)" "unprognostic (2.05e-1)" "unprognostic (3.93e-2)" "unprognostic (4.42e-2)" "unprognostic (1.97e-1)" "unprognostic (9.52e-3)" "unprognostic (2.22e-1)" "prognostic favorable (9.29e-4)" "unprognostic (3.27e-2)" "unprognostic (3.44e-1)" "unprognostic (3.23e-1)" "unprognostic (2.52e-2)" 9.0 5.5 4.7 4.6 5.9 0.6 7.8 5.5 4.4 7.7 10.0 5.0 2.0 8.9 3.3 5.2 6.9 6.9 12.1 4.4 4.4 18.8 19.2 28.2 2.3 7.3 5.8 11.5 12.6 9.7 1.8 14.5 6.3 7.9 2.9 21.3 6.1 8.8 4.2 4.1 2.1 9.9 6.6 6.3 6.8 15.5 5.4 1.0 15.9 5.5 2.2 6.2 3.8 7.7 26.0 10.9 23.1 20.7 16.9 18.8 26.7 34.5 27.1 37.2 26.6 48.2 24.7 0.0 16.9 55.7 13.0 9.2 35.7 14.3 46.9 0.0 11.0 26.3 25.4 24.9 17.5 12.5 27.6 14.3 10.7 24.6 22.9 30.8 25.1 3.7 18.9 1.4 28.6 7.5 0.0 8.3 22.0 0.7 9.3 0.0 21.1 14.0 52.7 6.9 1.5 11.7 84.2 72.7 11.1 36.5 17.6 4.2 37.8 13.8 38.2 8.2 25.1 0.0 0.0 0.3 13.5 5.7 24.7 0.0 0.3 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.4 0.0 0.0 0.0 4.7 5.9 5.5 4.4 4.4 4.4 7.3 5.8 6.3 6.6 5.4 7.7 27.8 262.8 65.4 23.2 0.4 24.0 9.3 6.3 8.6 5.4 15.0 11.4 30.0 37.1 24.0 7.3 64.6 15.4 1.4 0.7 27.4 16.3 36.9 26.7 26.6 27.4 1.2 3.6 62.1 14.6 9.8 25.0 9.2 35.4 19.0 39.5 17.2 39.0 10.5 0.0 98.1 0.2 4.1 15.6 7.7 26.9 17.7 9.0 12.4 129.3 7.6 11.7 0.0 52.3 44.0 30.3 0.1 21.1 0.8 29.3 0.0 24.7 11.5 58.6 26.3 34.2 24.2 41.8 19.7 7.7 15.3 6.6 3.2 19.9 0.4 12.2 WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 229.3;Endothelial cells: 221.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 212.1;RPTEC TERT1: 151.1;SK-MEL-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" 41.6 13.8 19.2 22.4 20.8 0.2 37.2 18.9 19.6 41.8 32.6 74.9 8.0 42.1 13.4 35.8 33.7 39.6 36.4 20.7 53.9 45.9 19.0 41.2 7.2 52.6 39.9 43.9 31.8 14.1 13.6 44.0 35.9 34.5 13.5 4.2 27.6 32.1 13.2 24.8 21.6 43.7 37.1 19.5 32.7 7.2 23.0 4.7 31.6 15.0 6.1 59.2 34.3 41.0 58.9 80.5 40.6 48.7 48.6 86.8 43.0 32.6 57.5 17.7 17.8 46.7 53.2 0.1 212.1 45.0 53.3 36.1 28.4 28.5 17.9 22.0 19.3 0.0 18.6 37.8 27.3 0.0 0.1 45.3 7.4 61.8 26.6 65.4 136.3 0.0 0.0 0.2 61.7 9.2 0.2 0.2 8.2 0.2 96.6 0.0 50.6 0.4 151.1 9.4 0.0 0.4 21.1 17.2 160.2 31.5 26.5 1.6 94.2 29.0 16.2 24.8 67.4 0.6 0.5 0.8 66.8 0.1 78.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.1 19.2 20.8 18.9 19.6 20.7 53.9 52.6 39.9 35.9 37.1 23.0 41.0 125.7 64.1 89.7 60.4 1.1 51.7 229.3 34.6 60.9 2.2 58.1 56.8 46.8 141.5 87.8 49.7 4.2 12.2 2.0 0.5 7.9 72.0 21.9 136.3 89.1 221.2 0.0 3.2 8.7 27.1 82.3 77.9 10.2 144.4 7.6 45.0 111.4 21.9 4.1 0.0 6.1 1.2 10.2 6.0 32.3 7.9 57.8 4.6 30.2 94.6 2.1 11.0 0.0 7.5 12.7 45.8 0.0 126.4 2.9 86.7 1.2 59.8 53.9 2.0 59.2 76.1 58.0 2.2 0.8 46.3 35.5 14.8 6.5 48.4 2.4 93.5 XKRX "XKR2, XPLAC" ENSG00000182489 "XK related X-linked" Q6PP77 X 100913445-100929433 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skin 1: 9.7" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Excitatory neurons: 4.3;Inhibitory neurons: 6.0;Microglial cells: 3.7;Oligodendrocytes: 5.5;Syncytiotrophoblasts: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "naive B-cell: 1.9;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.2" "Group enriched" "Detected in many" 18 "B-cells: 1.9;T-cells: 1.5" "Cell line enriched" "Detected in some" 5 "CACO-2: 8.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.35e-1)" "unprognostic (2.38e-2)" "unprognostic (4.51e-3)" "unprognostic (1.87e-1)" "unprognostic (8.53e-2)" "unprognostic (2.67e-2)" "unprognostic (2.96e-2)" "unprognostic (5.18e-2)" "unprognostic (3.69e-2)" "unprognostic (7.37e-2)" "unprognostic (5.70e-2)" "unprognostic (1.58e-2)" "unprognostic (5.60e-6)" "unprognostic (1.25e-1)" "unprognostic (2.60e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.18e-1)" 0.0 0.6 0.5 0.8 0.3 0.1 0.6 0.1 0.3 0.7 0.0 0.7 0.3 0.2 1.1 2.3 0.6 0.1 0.0 0.2 1.7 0.1 0.0 1.2 1.6 0.3 0.4 0.2 0.0 0.0 1.0 0.3 0.3 0.3 0.8 0.2 0.5 0.9 0.1 9.7 2.4 0.1 0.2 0.5 0.3 0.2 1.2 1.8 0.4 0.0 3.5 0.3 1.7 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 8.2 1.0 0.6 0.0 0.0 0.7 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 1.5 0.6 0.0 0.0 0.0 0.4 0.1 0.0 0.3 1.6 0.0 0.0 0.0 1.6 0.1 1.3 0.2 0.7 0.1 0.7 0.0 0.1 0.2 0.0 1.4 0.0 0.2 0.0 0.0 1.2 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 1.9 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.1 0.3 0.2 1.7 0.3 0.4 0.3 0.2 1.2 0.2 0.0 0.0 0.0 9.4 0.7 0.0 0.1 0.5 0.0 0.3 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 6.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 1.8 3.7 0.1 0.2 0.0 1.0 5.5 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.9 2.6 0.2 0.0 0.2 0.4 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 475.9" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 40.1;HSkMC: 21.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 7.5 0.9 0.1 3.7 0.1 0.2 3.0 0.1 0.1 3.7 0.1 5.5 99.0 2.4 0.1 2.2 6.3 4.3 5.3 0.1 0.1 156.0 23.1 2.1 0.5 0.2 0.1 1.8 0.3 0.3 0.1 1.2 0.1 1.8 6.3 0.0 1.5 0.4 0.5 4.4 166.6 6.0 0.1 0.3 3.4 0.1 0.1 1.0 1.4 2.4 0.4 7.8 4.0 0.1 0.0 0.0 0.5 0.0 8.2 40.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.4 1.2 0.0 1.3 2.8 0.2 0.2 0.4 2.0 0.1 0.0 2.8 0.4 1.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.2 0.5 11.4 5.9 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.0 0.0 10.0 1.1 0.0 0.0 0.0 0.4 18.5 0.8 0.0 0.3 12.8 0.0 1.0 3.6 0.0 0.0 1.0 1.8 1.0 0.0 0.0 3.1 0.0 0.1 0.0 21.0 0.0 0.1 0.0 475.9 75.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.0 1.2 0.9 0.0 8.4 0.0 XRCC2 FANCU ENSG00000196584 "X-ray repair cross complementing 2" O43543 7 152644776-152676141 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 14.1;Extravillous trophoblasts: 21.2;Granulosa cells: 20.2;Spermatocytes: 31.3;Spermatogonia: 19.1;Syncytiotrophoblasts: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065153 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Vesicles" "HPA065153: AB_2685422" "unprognostic (9.31e-3)" "unprognostic (8.25e-2)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (9.10e-2)" "unprognostic (2.52e-2)" "unprognostic (3.36e-5)" "unprognostic (9.98e-3)" "unprognostic (5.82e-3)" "unprognostic (4.04e-3)" "unprognostic (1.06e-3)" "unprognostic (2.43e-2)" "unprognostic (1.55e-15)" "unprognostic (4.52e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-1)" "unprognostic (1.73e-2)" 0.2 0.2 0.9 2.3 0.6 5.3 1.5 1.6 2.8 0.3 0.0 1.1 1.7 1.1 0.9 1.0 0.5 0.4 1.0 0.6 1.9 0.4 0.4 0.5 2.9 0.6 0.6 1.0 0.0 0.6 0.0 2.1 1.4 0.7 1.7 1.9 0.2 0.4 0.1 1.9 1.5 0.5 1.1 1.0 1.0 3.0 1.0 3.6 0.6 0.0 2.5 0.5 0.1 1.9 16.5 10.4 18.3 15.8 1.1 1.8 15.0 11.8 3.9 8.2 10.3 14.7 12.8 24.8 9.5 3.5 13.7 13.7 12.8 7.1 19.3 8.9 17.3 16.8 15.5 10.0 0.3 27.3 9.3 0.9 1.1 15.6 3.6 2.0 3.8 15.5 34.2 22.8 8.3 12.6 32.4 21.2 21.6 10.8 12.9 22.8 19.3 15.3 3.1 10.3 16.7 18.1 11.7 7.6 5.0 11.3 5.4 8.3 4.2 17.2 6.9 13.3 23.0 8.8 14.5 19.0 11.0 20.9 20.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.6 1.6 2.8 0.6 1.9 0.6 0.6 1.4 1.1 1.0 1.9 0.2 0.0 1.1 1.6 1.9 1.3 1.0 1.0 0.0 4.9 0.8 0.4 2.9 0.0 1.4 1.8 0.0 11.2 0.4 0.9 0.0 1.1 11.7 0.9 1.9 1.1 0.0 14.1 2.3 0.2 21.2 2.5 3.1 1.4 0.0 20.2 1.1 0.2 2.4 0.0 2.0 1.7 2.0 0.6 0.8 4.9 0.9 0.8 0.0 0.0 0.6 1.1 3.1 4.5 2.0 0.5 0.1 1.2 6.1 0.6 0.3 0.3 0.1 2.3 0.0 1.9 1.8 31.3 19.1 2.7 1.4 12.6 2.2 1.2 2.3 1.0 YBX2 "Contrin, CSDA3, MSY2" ENSG00000006047 "Y-box binding protein 2" Q9Y2T7 17 7288263-7294639 "Predicted intracellular proteins, Transcription factors" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 77 "testis: 551.1" "Group enriched" "Detected in some" 18 "Early spermatids: 346.9;Late spermatids: 427.3;Spermatocytes: 234.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 4.8;MCF7: 8.7;SH-SY5Y: 3.2;SK-BR-3: 3.9;T-47d: 12.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "CAB012332, HPA053904, HPA056744" Enhanced NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB012332: AB_776541, HPA053904: AB_2682302, HPA056744: AB_2683223" "unprognostic (1.76e-2)" "unprognostic (4.62e-3)" "unprognostic (3.99e-2)" "prognostic unfavorable (6.50e-5)" "unprognostic (9.80e-4)" "unprognostic (4.68e-2)" "unprognostic (2.23e-1)" "unprognostic (3.44e-1)" "unprognostic (1.41e-1)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-4)" "unprognostic (1.78e-2)" "unprognostic (2.15e-1)" "unprognostic (5.31e-1)" "unprognostic (2.35e-2)" 3.0 0.1 0.5 0.1 0.6 0.2 3.2 0.4 1.1 2.4 0.1 7.2 1.0 1.3 0.0 2.0 2.3 0.0 1.4 0.9 0.5 1.1 1.9 0.1 0.0 0.9 0.7 0.3 0.3 0.3 0.5 0.0 0.6 1.4 0.3 0.0 1.2 0.8 2.0 1.4 4.0 0.5 0.5 0.1 1.2 551.1 0.9 0.0 1.1 0.1 0.0 1.0 0.9 0.8 0.0 0.0 0.0 0.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 4.8 2.3 0.0 2.4 0.0 0.0 0.4 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 8.7 0.3 0.4 1.5 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 1.3 3.9 0.3 2.0 12.6 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 1.1 0.9 0.5 0.9 0.7 0.6 0.5 0.9 0.8 0.6 0.0 0.0 0.3 0.0 0.6 0.1 0.1 0.0 0.2 2.8 3.3 4.4 0.0 0.3 1.8 0.0 0.2 0.5 18.0 0.0 0.1 346.9 0.7 0.1 0.7 4.8 0.0 0.5 0.2 0.4 0.4 0.0 0.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 8.2 0.0 0.0 0.0 427.3 6.8 0.7 3.6 0.0 0.0 0.8 0.0 0.0 0.1 0.0 9.9 6.8 0.0 0.3 10.0 0.4 0.3 0.5 0.0 0.4 1.2 234.3 12.0 1.8 0.9 0.1 0.1 0.1 15.2 1.1 YBX3 "CSDA, CSDA1, dbpA, ZONAB" ENSG00000060138 "Y-box binding protein 3" P16989 12 10699089-10723323 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 4915.7;tongue: 1635.6" "Cell type enhanced" "Detected in many" "Early spermatids: 1418.1;Prostatic glandular cells: 1553.4;Skeletal myocytes: 1316.7;Urothelial cells: 1339.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 6.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034838 Approved Supported Cytosol NA NA 230000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA034838: AB_10670980" "unprognostic (1.93e-2)" "unprognostic (6.20e-2)" "unprognostic (3.56e-1)" "unprognostic (3.61e-2)" "unprognostic (4.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.10e-1)" "unprognostic (3.81e-2)" "unprognostic (2.91e-1)" "unprognostic (2.41e-1)" "unprognostic (3.23e-3)" "unprognostic (1.20e-1)" "prognostic unfavorable (6.17e-13)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.44e-1)" 250.4 96.7 17.6 77.5 17.6 151.1 200.2 18.8 25.5 152.1 28.4 249.1 37.5 136.8 47.3 271.0 166.7 65.0 469.9 16.5 22.3 194.1 53.8 209.5 32.9 25.4 22.4 134.6 291.0 18.6 84.1 72.5 23.9 177.1 58.8 82.8 218.1 67.5 4915.7 358.1 99.0 100.9 20.9 79.5 149.7 265.7 22.2 36.7 136.1 1635.6 54.6 225.4 204.8 19.7 117.2 90.3 41.4 136.1 165.7 310.7 307.4 173.4 142.7 138.7 132.0 160.4 259.5 109.3 57.7 130.3 96.5 215.5 173.3 338.1 124.6 1.2 325.2 91.3 123.6 108.4 198.3 171.7 10.4 343.3 452.3 124.2 414.6 148.9 313.6 152.3 123.1 0.4 154.7 112.6 137.8 141.9 435.5 103.7 76.9 76.9 192.6 127.4 192.6 150.0 52.2 0.3 129.1 130.9 174.1 288.0 37.1 133.9 221.3 94.5 282.6 108.4 201.5 0.5 38.1 13.4 133.1 0.2 104.8 0.0 4.2 0.0 0.6 4.2 0.0 1.6 0.0 1.5 3.2 6.5 0.0 1.6 0.8 0.8 2.4 0.1 0.1 1.0 17.6 17.6 18.8 25.5 16.5 22.3 25.4 22.4 23.9 20.9 22.2 19.7 680.9 150.6 164.4 14.0 192.8 764.9 1226.9 212.9 552.7 36.1 288.8 292.7 497.7 105.8 177.8 145.3 89.6 145.7 39.2 94.3 133.1 125.3 1418.1 563.0 402.1 563.1 67.6 1081.5 2.4 143.3 84.3 484.8 119.8 551.3 63.3 291.0 235.6 23.1 97.7 16.8 1.0 139.5 120.1 223.2 494.7 470.2 264.7 292.2 259.7 21.5 83.9 67.2 2.1 4.5 0.1 122.0 76.3 223.8 80.6 1553.4 43.9 240.4 240.4 365.4 124.9 1316.7 643.1 594.6 158.4 638.6 1050.5 125.7 72.5 70.8 157.4 1339.7 YWHAQ "14-3-3, HS1" ENSG00000134308 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta" P27348 2 9583967-9630997 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007925, CAB010286" Approved Supported Nucleoplasm,Cytosol NA NA 49000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB010286: AB_2218221, HPA007925: AB_1844340" "unprognostic (2.65e-2)" "unprognostic (3.99e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (1.53e-1)" "unprognostic (5.78e-3)" "prognostic unfavorable (9.83e-6)" "unprognostic (4.90e-3)" "unprognostic (2.98e-2)" "unprognostic (5.51e-2)" "unprognostic (6.18e-2)" "unprognostic (1.45e-1)" "unprognostic (2.95e-2)" "unprognostic (6.74e-2)" "unprognostic (9.75e-2)" "unprognostic (1.63e-1)" "unprognostic (4.39e-3)" 144.6 141.0 190.8 106.1 223.2 178.4 153.6 216.5 239.1 177.0 149.4 161.2 119.4 184.3 141.6 187.3 136.5 122.6 218.7 205.1 229.7 140.0 116.3 119.3 132.0 218.6 203.8 163.2 201.5 131.9 112.9 123.2 212.4 161.1 133.0 143.6 120.2 140.2 53.5 121.5 116.2 177.4 203.9 89.8 127.5 144.6 205.7 148.2 137.6 62.1 141.1 144.4 161.8 280.5 316.1 465.2 412.0 400.3 316.6 434.5 385.7 421.6 412.3 432.5 360.2 352.9 269.3 404.4 214.0 608.5 451.3 288.5 462.8 459.7 553.6 1003.0 374.8 378.8 268.9 379.9 241.1 369.1 219.7 295.8 264.5 473.6 305.9 394.9 493.5 285.6 378.5 236.8 539.3 219.3 658.2 374.4 700.7 351.9 527.5 473.0 533.3 497.4 478.8 276.9 390.1 659.9 384.1 392.2 317.3 343.8 244.4 187.0 453.9 539.6 380.7 473.4 654.4 239.3 351.4 526.6 461.8 378.9 458.8 99.5 102.7 120.5 207.8 137.8 255.6 151.9 192.8 223.5 144.2 147.8 103.6 170.1 31.1 252.0 137.0 73.1 208.4 344.1 190.8 223.2 216.5 239.1 205.1 229.7 218.6 203.8 212.4 203.9 205.7 280.5 186.6 51.3 67.3 26.1 144.0 316.7 366.5 339.0 143.4 201.4 198.4 153.7 82.6 90.1 143.4 136.1 27.1 261.6 189.9 209.9 416.7 371.5 281.9 132.9 175.8 191.0 187.1 179.2 57.3 283.7 615.3 242.0 115.2 131.6 125.0 152.5 84.9 97.9 215.3 572.0 45.1 129.2 270.6 111.9 228.3 360.5 174.0 132.3 295.3 30.0 195.0 229.2 155.5 39.7 186.6 261.2 150.9 250.5 187.9 323.7 135.9 278.8 111.7 105.8 197.2 191.5 312.7 432.2 205.8 252.1 355.3 238.6 217.7 252.9 186.5 457.3 YWHAZ "14-3-3-zeta, KCIP-1, YWHAD" ENSG00000164924 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta" P63104 8 100916523-100953388 "Plasma proteins, Predicted intracellular proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005065 Approved NA NA 320000000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB005065: AB_2218378" "unprognostic (4.70e-3)" "unprognostic (7.38e-3)" "unprognostic (8.09e-2)" "prognostic unfavorable (3.91e-4)" "unprognostic (1.83e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (2.28e-5)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.65e-1)" "unprognostic (3.72e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.03e-6)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" 379.0 262.9 246.2 374.2 324.1 527.2 251.7 147.4 343.0 269.6 88.3 475.2 327.3 275.6 220.9 892.8 243.9 333.0 187.3 366.2 269.6 224.9 190.9 275.8 429.3 163.3 195.7 227.7 191.5 233.3 109.0 339.2 222.5 265.8 445.9 285.3 244.8 291.2 95.0 399.4 375.4 356.5 170.1 272.8 365.4 226.8 276.9 434.8 289.7 168.9 566.1 501.0 343.2 205.0 1902.4 879.2 1605.4 457.7 396.6 490.9 808.0 877.6 1099.2 1124.6 1098.2 602.4 1149.5 816.5 857.1 1349.3 937.2 785.0 1025.5 1213.5 1630.1 765.1 454.2 779.5 579.0 378.1 524.8 311.5 840.3 475.4 1524.0 936.7 1430.1 923.8 1008.7 584.9 887.8 758.9 920.2 660.6 1357.1 535.4 548.0 2269.0 1026.7 569.7 468.6 544.8 1023.1 963.5 889.7 642.7 669.5 609.8 1365.4 1094.7 896.0 374.6 879.0 554.6 834.3 693.7 798.3 503.6 625.3 994.6 925.8 595.2 2303.2 1340.5 427.5 705.8 559.0 589.1 559.3 484.8 463.3 537.3 497.3 395.9 348.3 441.8 616.5 503.7 726.9 313.4 663.9 1087.2 246.2 324.1 147.4 343.0 366.2 269.6 163.3 195.7 222.5 170.1 276.9 205.0 199.4 250.0 228.9 43.1 637.6 1007.0 438.4 309.3 507.6 120.4 285.9 209.9 87.0 188.8 321.3 263.0 89.6 243.4 491.2 552.7 121.3 405.2 1092.9 359.6 245.6 216.0 265.3 137.3 150.2 421.3 551.6 277.4 448.5 578.8 452.9 122.1 183.1 104.5 276.3 134.6 92.5 525.2 244.1 303.5 641.2 2118.0 125.6 456.9 391.3 56.2 334.9 110.9 407.8 51.3 91.5 771.0 452.7 147.1 457.2 427.2 310.6 160.4 292.0 96.3 131.5 229.4 290.4 170.2 92.6 908.0 1184.7 408.9 596.5 116.5 371.7 794.9 ZAN ENSG00000146839 Zonadhesin Q9Y493 7 100733595-100797797 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Early spermatids: 15.0;Late spermatids: 16.2" "Cancer enriched" "Detected in single" 8 "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (3.69e-1)" "unprognostic (4.60e-2)" "unprognostic (5.83e-6)" "unprognostic (9.44e-2)" "unprognostic (4.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.97e-1)" "unprognostic (5.70e-2)" "unprognostic (4.10e-9)" "unprognostic (5.70e-2)" "unprognostic (2.58e-1)" "unprognostic (8.43e-2)" "unprognostic (3.06e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.1 0.1 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713576-97739862 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;lymphoid tissue: 79.9" "Group enriched" "Detected in many" 4 "dendritic cells: 101.0;NK-cells: 155.5;T-cells: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 41 "gdT-cell: 137.4;MAIT T-cell: 93.2;memory CD4 T-cell: 71.7;memory CD8 T-cell: 108.3;naive CD4 T-cell: 50.8;naive CD8 T-cell: 79.8;NK-cell: 112.2;T-reg: 80.1" "Group enriched" "Detected in many" 56 "NK-cells: 112.2;T-cells: 137.4" "Group enriched" "Detected in some" 11 "JURKAT: 121.0;MOLT-4: 183.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002625, HPA003134" Enhanced NA NA 14000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favorable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favorable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favorable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 3.3 1.3 0.5 28.0 0.6 24.8 1.9 0.5 0.9 1.7 0.7 4.0 5.8 1.4 0.5 2.3 2.2 5.4 1.4 0.5 0.7 2.8 3.9 8.7 57.0 0.8 1.3 0.8 1.0 0.4 1.1 0.9 0.7 2.5 1.5 0.0 2.3 0.8 2.0 2.4 18.5 0.5 0.6 35.5 6.7 2.7 1.2 79.9 3.5 2.8 17.7 4.9 2.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 121.0 0.0 0.7 0.0 0.0 183.4 0.5 0.1 0.0 0.0 7.2 0.1 9.1 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 14.1 0.1 0.0 0.0 0.3 0.3 0.5 137.4 0.4 93.2 0.2 71.7 108.3 0.3 1.6 50.8 79.8 2.2 112.2 1.0 0.9 80.1 64.2 0.5 0.6 0.5 0.9 0.5 0.7 0.8 1.3 0.7 0.6 1.2 0.6 0.8 9.6 13.6 0.3 3.9 1.5 0.0 0.0 0.0 0.0 0.8 0.5 3.0 0.0 0.0 0.0 0.0 0.1 101.0 0.2 1.9 0.2 1.0 1.6 0.5 0.8 0.0 8.8 0.2 0.0 0.0 1.8 4.6 0.4 2.5 0.1 2.5 0.7 2.2 0.0 0.2 0.0 0.0 2.8 2.2 0.7 0.0 3.4 1.8 2.8 5.0 0.0 155.5 0.0 0.1 0.0 0.0 0.0 28.0 0.1 0.0 0.5 0.0 0.0 0.0 14.3 0.6 1.3 2.1 0.2 1.4 0.0 105.6 0.1 0.1 0.2 ZBTB10 "FLJ12752, RINZF" ENSG00000205189 "Zinc finger and BTB domain containing 10" Q96DT7 8 80485619-80526265 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 142.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 48.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021554, HPA050569" Enhanced Enhanced Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA021554: AB_1858937, HPA050569: AB_2681179" "unprognostic (7.97e-2)" "unprognostic (3.53e-1)" "unprognostic (2.26e-1)" "unprognostic (6.67e-2)" "unprognostic (9.28e-2)" "unprognostic (8.97e-3)" "unprognostic (1.29e-2)" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (4.86e-1)" "unprognostic (3.66e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.52e-4)" "unprognostic (4.65e-3)" "unprognostic (2.40e-1)" "unprognostic (7.15e-2)" "unprognostic (2.63e-2)" 7.9 7.9 4.1 4.8 5.2 23.7 8.2 12.1 4.4 8.7 3.9 6.9 2.0 11.2 6.1 3.7 11.8 7.4 7.5 3.3 5.1 10.2 18.5 6.2 5.3 4.9 4.4 12.7 14.0 7.1 3.5 17.8 5.0 14.1 7.8 7.3 7.6 6.3 5.4 1.9 2.2 8.9 4.3 7.0 4.6 11.2 4.7 8.6 10.1 8.0 3.4 5.5 3.3 5.7 0.0 4.2 21.1 10.7 9.1 6.9 28.5 3.9 0.0 3.0 3.0 9.2 3.4 12.7 11.0 5.8 9.2 0.9 16.7 5.3 3.5 0.0 26.8 6.5 2.8 7.3 5.3 2.2 2.9 6.5 4.6 3.7 10.6 2.5 7.7 10.5 5.9 24.2 2.5 6.7 12.6 5.5 5.3 1.3 6.6 14.7 11.1 4.5 8.4 12.5 12.6 14.6 5.2 48.5 14.8 23.6 9.4 9.1 9.9 7.3 13.5 0.1 3.6 7.0 3.7 14.0 2.8 0.0 9.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.4 0.3 0.3 0.0 0.5 0.2 0.9 0.0 0.0 4.1 5.2 12.1 4.4 3.3 5.1 4.9 4.4 5.0 4.3 4.7 5.7 37.1 25.6 17.0 18.9 55.3 28.4 21.1 8.1 44.3 13.4 48.8 39.8 36.1 25.8 11.8 12.9 16.7 38.3 34.1 38.9 3.9 13.1 83.7 82.4 60.6 34.5 60.4 3.0 12.8 6.9 41.0 29.3 40.8 142.6 9.5 37.0 16.8 31.7 13.3 32.0 11.1 43.0 20.3 21.3 79.6 29.7 19.3 32.0 49.8 13.1 11.2 20.8 8.2 19.6 13.4 8.3 14.8 21.1 24.5 82.1 0.4 14.5 19.4 10.6 26.3 46.6 49.5 14.6 10.6 13.6 12.6 105.2 28.4 19.6 34.7 19.6 ZBTB22 "BING1, fru, fruitless, ZBTB22A, ZNF297, ZNF297A" ENSG00000236104 "Zinc finger and BTB domain containing 22" O15209 6 33314406-33317942 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043848 Approved Nucleoplasm No No "Cluster 2: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA043848: AB_10961146" "unprognostic (1.32e-1)" "unprognostic (2.87e-1)" "unprognostic (3.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.38e-1)" "unprognostic (2.82e-1)" "unprognostic (1.31e-1)" "unprognostic (1.55e-2)" "unprognostic (2.06e-1)" "unprognostic (6.88e-2)" "unprognostic (4.98e-2)" "unprognostic (1.81e-1)" "unprognostic (6.54e-3)" "unprognostic (1.67e-2)" "unprognostic (2.86e-1)" "unprognostic (1.66e-2)" "unprognostic (9.32e-3)" 10.2 15.1 1.2 2.6 1.2 2.1 11.3 1.1 3.5 15.6 0.7 10.4 4.7 15.6 8.5 13.3 12.6 1.7 10.6 1.2 0.9 11.9 10.1 12.0 1.1 2.1 1.3 14.9 12.2 11.6 10.5 2.3 1.4 12.1 4.2 5.7 12.0 3.8 8.6 19.2 11.6 3.0 1.5 13.7 11.8 6.1 1.0 5.3 15.1 3.9 3.9 12.0 13.2 1.4 0.3 0.3 8.5 4.4 8.3 3.3 3.5 7.5 7.3 7.1 4.6 0.1 1.9 1.9 5.6 12.5 9.1 0.6 0.3 4.6 5.2 11.7 2.8 7.5 4.4 4.1 0.0 0.0 2.8 10.8 10.0 0.3 2.6 9.8 0.7 6.3 2.9 7.8 2.6 4.7 4.6 6.7 0.0 0.4 2.2 0.5 0.1 4.2 6.3 0.4 9.7 0.6 0.7 0.4 4.3 5.0 0.7 0.4 10.7 3.9 4.5 0.2 0.2 4.3 4.5 1.9 5.6 1.1 4.3 0.8 0.2 0.8 0.3 0.3 0.1 0.5 0.4 0.2 0.2 0.3 0.7 0.1 0.3 0.1 0.2 0.4 0.1 0.2 1.2 1.2 1.1 3.5 1.2 0.9 2.1 1.3 1.4 1.5 1.0 1.4 9.4 0.0 5.0 2.6 7.3 6.4 16.3 6.0 8.6 20.1 9.9 7.6 4.3 4.3 4.9 7.3 8.4 6.3 3.3 9.8 23.5 11.0 1.6 8.3 5.2 7.7 7.7 4.0 2.8 7.1 4.6 6.7 5.6 6.9 3.8 6.5 7.9 2.0 5.3 20.2 2.8 8.7 12.2 4.4 4.0 1.8 9.3 5.3 1.8 3.7 12.1 18.2 8.2 3.5 2.6 6.5 8.6 6.4 4.0 10.9 7.6 8.3 6.0 21.2 13.1 10.0 7.6 2.2 2.0 8.1 7.4 10.1 4.9 8.0 5.8 11.8 ZBTB33 "kaiso, WUGSC:H_DJ525N14.1, ZNF-kaiso, ZNF348" ENSG00000177485 "Zinc finger and BTB domain containing 33" Q86T24 X 120250752-120258398 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000755, CAB001980, HPA005732" Approved Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB001980: , HPA000755: AB_1079167, HPA005732: AB_1079166" "unprognostic (9.14e-3)" "unprognostic (1.45e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.47e-2)" "unprognostic (6.13e-2)" "unprognostic (1.72e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (4.51e-2)" "unprognostic (5.08e-3)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (6.44e-2)" "unprognostic (2.59e-2)" 6.4 7.0 6.4 8.5 7.0 19.5 15.4 7.1 9.0 6.8 4.7 6.8 7.7 6.2 9.4 9.9 8.2 7.3 4.9 6.4 9.2 6.4 19.0 8.7 13.2 7.3 8.7 9.7 8.4 13.7 4.8 8.8 8.5 7.4 6.5 5.7 10.4 6.0 5.4 18.8 6.4 4.8 8.4 11.5 8.6 5.7 9.3 16.2 10.2 7.7 12.8 8.0 4.8 9.7 13.6 12.9 19.6 18.1 15.9 17.8 23.4 10.3 13.5 11.7 14.5 9.0 11.7 19.5 18.8 10.4 15.7 20.7 31.9 15.7 15.3 22.0 21.6 20.3 20.3 12.7 11.6 21.2 22.7 12.7 19.9 11.2 17.6 17.1 20.9 18.7 13.5 23.2 14.6 15.6 19.2 14.1 24.3 20.9 15.3 21.9 14.9 32.0 12.5 22.2 35.6 15.2 20.9 21.3 25.3 14.9 11.5 29.6 19.6 9.5 6.9 14.3 18.5 12.7 13.1 24.7 12.6 29.4 11.9 11.5 4.2 5.6 2.9 6.4 5.0 2.4 3.8 3.9 6.2 2.2 4.6 3.4 0.9 4.0 4.2 6.7 3.5 3.6 6.4 7.0 7.1 9.0 6.4 9.2 7.3 8.7 8.5 8.4 9.3 9.7 15.7 16.0 7.0 3.9 7.9 12.7 7.8 5.1 12.5 4.5 11.5 13.1 5.2 8.6 11.9 1.8 0.0 7.7 21.7 5.3 1.9 5.5 0.1 12.9 8.7 8.5 8.4 10.3 3.4 6.7 8.7 7.9 7.1 10.3 0.0 16.0 7.9 16.6 7.6 3.3 4.6 7.0 6.1 12.8 10.3 0.4 4.4 8.2 3.6 3.7 14.6 7.0 14.4 5.0 4.6 6.9 5.7 2.6 5.4 9.5 6.8 4.0 15.3 1.6 6.6 6.9 4.1 5.0 10.0 12.7 13.1 9.3 8.7 11.2 6.0 11.9 ZBTB45 "FLJ14486, ZNF499" ENSG00000119574 "Zinc finger and BTB domain containing 45" Q96K62 19 58513530-58538911 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035754, HPA075485" Uncertain Approved "Nuclear bodies,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "Nuclear bodies" "HPA035754: AB_10603461, HPA075485: " "unprognostic (1.38e-1)" "unprognostic (7.12e-2)" "unprognostic (2.31e-1)" "unprognostic (7.34e-2)" "unprognostic (2.60e-1)" "unprognostic (4.50e-2)" "unprognostic (2.76e-3)" "unprognostic (2.19e-2)" "unprognostic (2.63e-2)" "unprognostic (3.02e-1)" "unprognostic (1.79e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.38e-4)" "unprognostic (2.08e-1)" "unprognostic (1.06e-1)" "unprognostic (5.47e-2)" "unprognostic (1.40e-1)" 7.9 8.5 6.5 5.1 6.7 4.9 8.6 5.2 11.4 9.9 1.9 10.3 6.1 12.0 1.1 10.1 9.5 3.1 9.1 7.1 4.9 7.7 6.9 6.1 4.2 8.9 6.4 9.3 8.2 4.2 7.1 3.1 8.3 9.5 1.6 2.1 9.0 4.1 10.3 12.7 7.6 2.4 4.5 8.0 8.3 4.9 6.7 3.3 8.3 3.0 2.3 10.5 9.0 7.4 21.3 29.7 7.6 11.7 7.7 6.6 9.6 11.8 4.8 3.0 2.9 5.8 13.4 31.9 15.6 6.6 8.4 13.2 4.2 10.7 1.1 21.4 55.3 17.3 15.1 7.1 4.9 11.1 11.1 6.3 7.4 4.7 3.9 5.6 6.2 32.1 16.0 1.8 4.6 14.2 17.4 11.6 10.6 12.5 26.1 13.8 4.7 19.4 6.2 19.4 23.4 16.7 8.7 22.5 6.1 4.6 33.4 7.6 13.1 12.9 5.6 4.3 11.7 34.8 27.2 15.9 14.7 4.6 8.4 5.8 5.0 10.2 5.7 7.6 6.8 4.4 3.9 5.3 5.3 5.0 4.6 3.4 4.4 5.5 9.1 6.4 3.7 4.7 6.5 6.7 5.2 11.4 7.1 4.9 8.9 6.4 8.3 4.5 6.7 7.4 3.3 9.6 0.5 2.9 5.6 1.7 3.7 5.5 2.2 4.2 4.5 4.6 3.3 1.5 4.0 12.9 0.0 8.9 5.1 6.3 5.9 10.6 0.6 3.4 4.6 5.0 10.3 7.4 1.9 8.9 8.0 3.9 8.6 3.8 0.0 5.6 8.6 4.5 6.6 6.7 2.0 4.6 8.2 6.8 2.4 1.3 5.9 3.7 7.2 0.0 12.3 3.7 7.2 1.5 1.6 8.8 2.6 9.8 3.6 3.8 5.9 5.6 3.8 3.0 13.1 2.5 5.1 5.2 5.9 3.5 2.7 5.6 3.1 4.8 6.0 2.6 ZBTB7B "c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B" ENSG00000160685 "Zinc finger and BTB domain containing 7B" O15156 1 155002630-155018522 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.2;Proximal enterocytes: 158.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006811, HPA025820" Enhanced Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA006811: AB_1859046, HPA025820: AB_1859045" "unprognostic (5.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (4.36e-2)" "unprognostic (2.43e-1)" "unprognostic (4.95e-3)" "unprognostic (9.55e-2)" "unprognostic (1.41e-1)" "unprognostic (3.72e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.46e-2)" "unprognostic (5.35e-2)" "unprognostic (1.11e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" "unprognostic (1.53e-2)" 24.9 35.3 12.9 18.1 15.8 30.0 27.9 15.8 12.9 25.3 11.7 55.4 61.9 16.1 6.4 95.4 17.9 11.0 25.2 11.2 13.6 19.7 48.4 25.0 16.2 18.3 17.5 12.7 29.9 15.6 20.0 9.0 17.3 30.5 18.6 6.5 40.2 12.8 40.6 111.9 71.2 9.9 15.8 31.6 37.7 6.1 17.7 9.0 25.5 17.6 15.2 20.4 44.4 17.9 16.5 29.0 2.5 8.8 12.7 7.2 34.7 11.1 13.1 11.4 13.2 19.5 23.4 7.2 19.5 12.6 9.1 24.5 8.1 15.7 2.4 39.4 9.1 12.0 51.4 13.1 18.6 9.2 31.7 9.4 54.8 15.6 19.3 15.3 9.1 1.1 17.3 32.2 6.7 31.2 0.2 20.7 8.7 26.4 23.8 6.8 1.9 45.6 17.2 16.9 16.1 16.5 21.4 56.5 8.9 10.6 35.2 30.7 7.7 7.4 12.9 14.8 9.5 38.1 25.1 7.6 17.3 30.3 8.6 0.4 1.5 1.3 0.6 1.4 0.2 0.6 0.7 0.3 0.9 0.7 0.6 0.2 2.3 0.7 1.2 0.0 1.0 2.5 12.9 15.8 15.8 12.9 11.2 13.6 18.3 17.5 17.3 15.8 17.7 17.9 6.5 9.6 0.0 11.1 8.5 35.2 9.3 8.8 29.6 13.6 35.2 15.6 2.6 18.6 7.1 5.5 2.1 11.9 6.9 135.2 11.7 13.3 4.3 15.4 6.7 5.6 6.7 6.1 1.0 15.1 14.6 4.9 27.5 21.3 5.7 2.8 6.1 29.9 14.8 16.8 1.1 32.7 14.2 28.7 40.3 8.3 9.0 20.7 16.0 4.7 25.8 5.4 11.3 0.0 8.6 16.8 57.7 7.2 6.8 24.9 158.5 10.0 4.2 10.3 0.0 3.2 5.7 0.5 1.2 51.7 53.6 27.5 11.3 4.4 38.5 24.4 ZCCHC2 "C18orf49, FLJ20222, FLJ20281, KIAA1744" ENSG00000141664 "Zinc finger CCHC-type containing 2" Q9C0B9 18 62523025-62587709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 143.8;Late spermatids: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040943 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA040943: AB_10795496" "unprognostic (9.32e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.84e-3)" "unprognostic (1.40e-1)" "unprognostic (4.07e-2)" "unprognostic (4.79e-2)" "unprognostic (2.60e-1)" "unprognostic (1.93e-1)" "unprognostic (8.25e-2)" "unprognostic (2.32e-2)" "unprognostic (1.30e-1)" "unprognostic (5.12e-2)" "unprognostic (2.45e-1)" "unprognostic (3.72e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" 10.7 5.5 6.2 5.8 6.6 26.5 9.1 9.3 8.2 6.7 6.0 7.1 6.7 6.3 5.9 5.5 7.8 8.6 8.5 5.5 6.9 5.5 23.3 10.2 7.0 7.2 6.8 8.0 6.2 5.8 8.0 8.1 6.7 7.3 5.4 10.0 37.2 5.3 12.2 11.6 7.5 5.8 5.3 9.0 6.4 12.0 6.6 7.6 7.3 7.3 6.3 7.9 6.5 11.5 8.0 6.8 5.8 11.5 17.1 7.3 10.9 4.5 6.7 10.5 10.4 3.7 4.8 22.4 5.8 7.4 8.6 13.2 18.6 9.9 4.3 15.5 8.8 5.9 15.6 25.2 5.9 11.4 8.3 7.2 12.6 6.7 12.3 7.6 19.9 9.9 6.4 7.3 3.5 6.5 7.5 4.8 3.7 5.8 6.7 9.7 6.1 0.1 7.3 8.0 7.2 4.5 7.5 16.8 6.6 10.2 5.9 8.9 8.6 10.3 7.0 4.1 6.5 2.8 5.8 9.4 7.6 4.7 3.9 0.0 0.3 0.8 0.5 0.5 0.4 0.1 0.3 0.4 0.1 0.4 0.6 0.4 1.5 0.2 0.1 0.3 0.4 0.1 6.2 6.6 9.3 8.2 5.5 6.9 7.2 6.8 6.7 5.3 6.6 11.5 23.1 25.6 18.8 28.1 10.8 26.6 16.9 7.5 10.8 33.1 15.2 13.2 18.8 20.0 12.4 16.5 54.2 7.4 33.6 10.2 3.9 6.8 143.8 24.1 12.3 28.8 12.6 8.2 48.5 6.2 10.9 9.7 10.2 27.5 2.5 4.4 17.5 35.4 14.1 43.7 33.9 15.5 2.0 44.4 22.0 158.6 8.1 30.6 7.2 29.0 11.9 7.7 9.2 37.2 51.7 5.1 9.1 7.9 10.7 16.5 8.4 5.3 10.8 19.5 6.6 15.6 15.0 16.3 15.2 15.3 18.5 6.8 22.6 5.6 11.5 12.2 ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type palmitoyltransferase 12" Q96GR4 9 128720870-128724127 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Intermediate filaments" "HPA059339: AB_2683985" "unprognostic (2.05e-1)" "unprognostic (5.81e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-3)" "unprognostic (5.34e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-1)" "unprognostic (6.42e-2)" "unprognostic (9.97e-2)" "unprognostic (9.41e-2)" "unprognostic (1.09e-2)" "unprognostic (8.82e-3)" "unprognostic (2.18e-1)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" 18.8 23.9 7.8 15.5 7.7 41.3 19.3 7.5 9.9 16.8 8.4 40.5 26.3 12.9 7.1 67.8 12.0 14.1 13.7 7.4 8.8 30.6 52.3 23.3 20.0 9.6 7.8 7.4 67.1 9.8 11.3 16.3 8.4 26.6 13.7 0.5 43.2 12.5 15.6 42.4 36.8 6.3 8.4 31.7 49.2 24.7 10.5 12.4 16.2 4.1 13.7 18.7 30.5 9.7 53.5 127.6 6.0 31.3 17.6 12.1 59.4 32.8 28.8 34.5 22.9 109.6 61.5 37.3 29.6 25.5 62.9 139.8 13.0 65.0 3.8 65.0 31.7 20.1 92.7 49.1 34.7 33.1 87.1 19.9 44.7 29.6 11.0 17.7 25.6 65.6 18.8 93.6 7.1 187.3 45.9 66.2 26.8 118.8 107.6 21.0 21.0 108.4 28.7 43.4 42.1 30.4 46.2 64.1 18.3 9.6 98.9 35.6 27.5 0.1 36.9 25.9 45.8 58.1 106.8 17.3 61.3 38.4 41.4 231.1 122.3 385.6 105.1 123.9 91.2 94.6 95.9 101.5 100.1 111.0 99.2 91.4 269.5 90.5 150.0 244.7 130.9 101.0 7.8 7.7 7.5 9.9 7.4 8.8 9.6 7.8 8.4 8.4 10.5 9.7 10.0 16.0 12.0 1.3 31.8 16.2 43.3 94.0 10.8 1.2 55.5 30.4 14.8 77.2 59.0 46.0 0.0 183.9 39.1 171.0 13.7 106.8 73.2 20.7 11.5 21.1 51.2 51.1 0.6 200.0 224.0 14.2 38.7 52.5 18.4 13.7 35.7 55.3 137.0 0.0 0.5 108.5 67.1 62.2 20.9 30.0 9.6 46.5 42.7 6.5 115.3 18.4 81.4 0.5 2.0 133.8 167.7 7.2 43.3 56.5 186.0 48.5 20.1 2.0 6.6 5.4 16.3 36.0 18.6 55.2 28.1 134.1 34.1 22.0 110.0 77.5 ZDHHC3 "DHHC3, GODZ, ZNF373" ENSG00000163812 "Zinc finger DHHC-type palmitoyltransferase 3" Q9NYG2 3 44915257-44976185 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 8 "Early spermatids: 570.7;Late spermatids: 1564.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012465, HPA016616" Approved Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "CAB012465: , HPA016616: AB_1859004" "unprognostic (2.80e-1)" "unprognostic (6.07e-2)" "prognostic favorable (3.43e-4)" "unprognostic (3.10e-2)" "unprognostic (2.47e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.37e-4)" "unprognostic (4.20e-2)" "unprognostic (1.04e-1)" "unprognostic (6.37e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "prognostic favorable (1.81e-8)" "unprognostic (2.64e-1)" "unprognostic (1.49e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-2)" 50.1 48.6 23.0 25.7 21.5 82.8 36.3 27.9 22.9 42.2 25.8 70.6 44.1 35.4 24.5 58.0 27.5 32.0 36.3 25.8 21.1 40.3 32.3 41.9 21.9 28.7 25.1 28.9 22.2 46.0 13.4 28.7 29.8 35.6 64.6 16.6 33.3 40.1 43.7 70.0 58.1 36.3 25.8 29.6 55.3 80.8 27.0 26.9 38.6 52.8 33.3 53.6 42.5 25.3 62.5 53.3 41.0 49.1 219.2 100.5 46.8 58.8 80.7 78.3 66.5 61.0 85.1 58.7 31.4 107.9 52.8 80.7 68.4 104.3 74.6 61.7 29.3 55.9 57.9 45.7 50.6 136.3 43.0 92.5 111.6 73.6 67.2 59.8 79.6 63.8 73.8 51.3 78.1 42.9 46.2 73.6 60.7 155.9 96.7 29.9 40.6 47.0 66.7 176.7 14.6 52.8 70.3 70.5 36.4 70.4 57.4 88.2 78.0 55.4 55.2 60.2 66.3 32.2 66.6 59.6 55.2 198.9 39.4 53.7 24.5 32.6 14.6 12.3 13.3 10.7 11.0 16.1 26.8 12.6 10.2 14.4 25.4 14.5 17.5 15.3 17.1 13.6 23.0 21.5 27.9 22.9 25.8 21.1 28.7 25.1 29.8 25.8 27.0 25.3 41.5 41.7 82.1 7.5 17.8 48.2 42.1 40.8 48.9 9.8 24.4 20.8 29.2 24.3 27.1 53.3 6.2 47.7 23.4 105.6 72.4 46.6 570.7 18.8 31.2 34.1 35.9 68.8 15.7 79.0 59.4 26.4 69.3 26.6 19.0 21.5 35.7 29.4 49.5 15.2 15.6 78.2 38.7 34.0 26.7 1564.3 51.9 37.4 24.9 18.7 35.6 25.1 34.0 15.1 11.2 115.8 73.1 44.8 26.2 73.7 112.9 30.1 20.9 10.6 19.7 15.6 31.9 104.5 45.3 70.5 60.2 101.7 25.0 26.1 72.8 128.9 ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA014670: AB_2257442" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-3)" "unprognostic (1.74e-3)" "unprognostic (4.36e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.76e-1)" "unprognostic (4.72e-3)" "unprognostic (2.16e-1)" "unprognostic (6.80e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-3)" 29.0 21.7 8.3 27.2 7.8 29.2 25.8 8.3 9.5 27.0 11.0 36.4 29.6 22.3 24.1 60.9 25.0 27.9 27.9 7.5 9.2 28.2 36.7 29.0 24.4 8.5 8.9 20.7 31.6 45.3 12.6 36.7 8.7 28.0 34.4 35.9 35.0 26.7 40.9 45.2 31.0 29.0 6.9 25.5 30.2 36.2 10.9 30.6 36.9 45.5 35.0 42.3 28.7 8.9 80.3 86.2 33.7 34.7 74.9 57.4 64.9 72.8 89.8 61.8 46.3 52.3 97.0 53.4 91.9 89.5 53.1 110.1 53.6 88.9 55.4 66.5 24.4 45.8 40.1 49.3 81.5 85.9 73.7 81.3 79.3 88.8 92.9 51.1 71.0 45.6 61.5 66.2 79.7 48.4 49.1 29.3 41.1 61.0 52.2 47.8 66.6 67.1 74.8 115.2 25.3 30.7 67.6 77.0 78.5 45.4 81.9 52.6 80.7 76.5 40.7 82.9 52.2 48.2 63.0 45.9 59.1 44.4 68.0 11.6 5.2 7.1 6.9 6.8 8.3 5.8 6.7 6.0 5.4 5.7 6.7 6.9 6.9 5.0 8.1 9.0 7.0 6.8 8.3 7.8 8.3 9.5 7.5 9.2 8.5 8.9 8.7 6.9 10.9 8.9 28.8 16.0 10.5 14.7 13.4 16.2 12.7 13.7 16.5 21.4 20.4 15.2 21.6 12.8 19.8 12.9 37.5 10.1 20.3 41.3 3.9 14.4 21.3 19.9 22.1 17.1 11.5 10.8 16.4 18.2 9.9 15.5 15.8 35.5 19.7 24.9 16.1 15.1 13.0 13.5 17.9 17.5 18.3 16.3 10.2 9.8 11.8 18.4 1.8 14.0 16.0 14.0 17.5 17.6 14.7 26.0 20.8 7.5 12.4 15.1 22.9 11.4 17.4 47.7 0.0 18.4 18.5 13.3 7.1 31.5 19.9 18.6 15.9 16.8 19.7 20.5 ZFAND4 "ANUBL1, FLJ40185" ENSG00000172671 "Zinc finger AN1-type containing 4" Q86XD8 10 45615500-45672780 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "testis: 37.4" "Group enriched" "Detected in many" 6 "Early spermatids: 414.6;Late spermatids: 689.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "Daudi: 34.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057543, HPA074103" Enhanced Approved "Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 83: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA057543: AB_2683461, HPA074103: " "unprognostic (1.57e-1)" "unprognostic (1.53e-2)" "unprognostic (6.90e-2)" "unprognostic (3.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.31e-2)" "unprognostic (1.62e-1)" "unprognostic (1.46e-3)" "unprognostic (2.55e-1)" "unprognostic (3.16e-1)" "unprognostic (8.85e-5)" "unprognostic (3.23e-1)" "unprognostic (9.15e-3)" "unprognostic (1.18e-1)" "unprognostic (6.19e-2)" "unprognostic (1.28e-1)" "unprognostic (4.07e-3)" 2.2 3.3 1.8 2.0 1.9 2.2 3.0 4.0 2.1 2.6 1.9 2.1 2.1 2.4 1.5 1.6 2.7 1.4 2.5 1.5 2.4 2.1 3.8 2.2 4.9 2.3 2.4 2.4 2.4 1.4 3.0 1.2 2.3 2.6 2.2 2.2 2.3 1.7 2.2 3.2 2.0 1.8 2.1 2.5 1.9 37.4 2.3 3.2 3.4 1.6 4.7 2.1 2.2 2.4 1.0 0.7 1.4 2.1 3.2 2.5 0.0 1.4 2.4 1.3 1.4 0.0 1.0 34.6 1.7 0.9 1.9 0.3 1.1 0.9 1.6 5.6 1.7 1.0 1.1 0.8 2.4 0.0 6.8 2.2 1.7 0.5 1.3 1.0 1.2 4.5 0.9 5.8 1.5 0.1 3.3 0.7 1.4 1.1 0.9 0.5 1.1 0.0 1.1 0.9 2.7 1.8 1.1 1.3 1.1 1.5 2.9 1.9 1.1 0.5 2.5 2.1 1.7 4.6 8.2 0.0 1.0 3.4 0.6 0.3 0.2 0.0 0.4 0.1 0.5 0.4 0.3 0.3 0.1 0.3 0.3 0.4 0.0 0.7 0.4 0.1 0.3 0.1 1.8 1.9 4.0 2.1 1.5 2.4 2.3 2.4 2.3 2.1 2.3 2.4 2.5 6.4 3.1 22.5 7.6 0.8 3.3 1.0 5.7 7.9 4.0 2.2 3.9 4.3 0.7 1.8 27.1 0.3 7.1 3.7 1.9 1.1 414.6 6.5 3.4 2.8 1.8 5.7 3.3 1.8 0.4 3.1 4.6 1.8 2.5 3.0 3.3 5.6 2.2 3.3 23.2 2.5 0.0 2.5 1.0 689.8 6.5 2.3 3.6 13.1 2.2 4.1 1.0 47.3 39.7 1.3 0.5 3.0 10.3 3.9 1.6 3.7 8.9 8.7 6.6 4.5 2.2 86.3 13.5 3.2 2.3 0.1 7.0 4.0 2.7 1.9 ZFP64 "dJ548G19.1, dJ831D17.1, FLJ10734, FLJ12628, ZNF338" ENSG00000020256 "ZFP64 zinc finger protein" Q9NTW7 20 52051663-52204308 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035112, HPA058387" Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA035112: AB_10672859, HPA058387: AB_2683702" "unprognostic (3.86e-2)" "unprognostic (8.84e-2)" "unprognostic (2.34e-1)" "unprognostic (4.61e-3)" "unprognostic (9.22e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.86e-7)" "unprognostic (4.68e-2)" "unprognostic (5.49e-2)" "unprognostic (3.35e-1)" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (1.35e-3)" "unprognostic (2.22e-2)" "unprognostic (2.30e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" 4.2 4.8 5.8 5.7 5.5 5.3 4.6 5.2 5.5 5.7 3.0 6.3 6.6 5.7 4.2 7.0 6.7 5.3 4.8 5.1 3.4 4.7 5.2 4.5 6.6 4.7 3.4 7.8 5.6 7.2 4.7 4.3 4.6 6.3 5.7 5.0 5.8 5.7 5.4 11.2 5.9 5.5 2.6 5.7 5.9 6.6 4.5 7.3 6.8 4.5 5.3 5.6 6.1 5.6 35.1 19.6 14.7 35.1 7.2 13.0 21.0 11.9 17.3 25.5 21.1 18.8 14.3 15.5 23.2 21.5 21.1 46.2 12.0 26.6 15.6 6.6 37.5 9.3 35.0 20.1 19.9 10.4 6.6 11.3 39.4 13.0 14.8 13.0 17.6 16.4 11.2 19.5 6.4 14.6 14.5 8.9 14.8 19.0 15.1 15.9 7.6 15.6 12.1 13.9 15.2 18.0 23.1 28.6 22.5 12.0 19.2 12.3 11.6 18.0 26.1 19.7 7.7 21.1 20.6 12.6 17.2 10.3 12.2 5.1 3.3 8.1 4.5 1.8 3.3 5.1 3.4 3.6 4.2 3.2 3.8 3.7 1.8 5.3 4.8 4.1 3.3 2.8 5.8 5.5 5.2 5.5 5.1 3.4 4.7 3.4 4.6 2.6 4.5 5.6 4.7 3.2 3.3 7.2 5.4 8.7 4.3 5.4 19.9 5.1 5.1 3.9 4.0 4.3 2.5 0.0 2.1 4.3 6.2 7.5 7.9 8.2 7.4 3.9 4.4 4.2 6.7 5.5 18.0 5.8 8.5 5.9 9.7 3.9 7.0 5.2 9.3 6.1 4.0 1.7 15.5 9.5 8.2 4.1 4.2 9.1 6.5 2.9 3.6 14.0 4.0 2.7 7.2 15.6 18.6 5.4 6.0 7.2 11.6 3.5 5.3 4.9 4.0 4.7 6.6 3.8 5.5 19.7 2.9 11.3 13.4 1.2 5.8 3.9 9.0 2.6 ZFPM1 "FOG, FOG1, ZC2HC11A, ZNF89A" ENSG00000179588 "Zinc finger protein, FOG family member 1" Q8IX07 16 88453280-88537031 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 35.3;Muller glia cells: 58.0;Theca cells: 37.4" "Cancer enhanced" "Detected in all" "stomach cancer: 12.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 19.3;K-562: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046603 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA046603: AB_2679718" "unprognostic (1.29e-1)" "unprognostic (2.42e-1)" "unprognostic (3.08e-2)" "unprognostic (3.32e-2)" "unprognostic (1.13e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-1)" "unprognostic (7.13e-3)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (5.58e-2)" "unprognostic (3.05e-2)" "unprognostic (2.49e-4)" "unprognostic (1.99e-2)" "unprognostic (3.32e-1)" "unprognostic (4.89e-2)" "prognostic favorable (4.24e-4)" 2.1 2.5 4.8 1.9 2.4 9.2 1.9 5.7 5.8 2.3 4.2 1.7 12.4 2.2 1.0 1.8 4.0 1.5 4.8 5.8 2.1 3.7 8.6 2.1 2.7 3.5 3.2 2.2 10.4 1.4 5.6 0.8 2.6 3.2 0.8 0.7 2.8 1.3 1.6 3.7 6.8 0.2 1.6 4.9 13.7 5.7 3.3 1.5 4.0 0.3 1.2 2.3 2.0 1.6 1.4 3.8 2.8 5.9 0.5 0.1 11.9 4.0 0.5 1.3 0.4 12.1 1.5 5.9 3.0 0.6 1.4 9.5 0.1 3.3 0.3 4.6 2.5 19.3 8.1 10.7 2.1 1.1 6.2 1.3 2.1 1.4 0.5 1.4 1.3 1.6 29.2 0.4 1.0 7.3 6.9 7.0 1.9 9.3 3.2 2.0 1.3 2.9 1.3 4.8 7.7 12.8 4.9 0.3 3.9 1.4 3.1 3.1 4.8 4.9 3.1 2.2 0.8 1.4 1.0 0.5 1.4 2.3 4.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 2.4 5.7 5.8 5.8 2.1 3.5 3.2 2.6 1.6 3.3 1.6 16.7 3.2 2.2 12.4 4.8 0.9 6.1 0.7 0.0 20.7 13.5 25.8 17.2 5.7 0.4 1.8 29.2 0.4 27.5 10.8 1.9 1.3 0.7 24.1 23.7 6.3 6.0 4.8 6.8 5.1 0.2 10.9 14.3 20.1 0.0 16.0 5.0 8.8 0.9 35.3 8.0 6.7 0.0 5.3 1.2 1.1 0.9 7.5 1.8 8.4 1.6 58.0 2.1 5.5 13.4 2.9 6.2 1.5 9.5 1.4 1.3 1.3 0.4 23.9 0.0 16.1 12.4 0.7 1.0 1.9 1.4 0.3 9.6 37.4 5.2 2.1 ZG16B "HRPE773, JCLN2, PRO1567" ENSG00000162078 "Zymogen granule protein 16B" Q96DA0 16 2830169-2839585 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 717 "salivary gland: 63926.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 194.0;Basal respiratory cells: 181.6;Breast glandular cells: 154.9;Club cells: 343.9;Intestinal goblet cells: 232.2;Prostatic glandular cells: 398.1;Urothelial cells: 357.4" "Cancer enhanced" "Detected in many" "prostate cancer: 47.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.3;intermediate monocyte: 11.4;non-classical monocyte: 7.4" "Lineage enriched" "Detected in many" 7 "monocytes: 11.4" "Cell line enhanced" "Detected in some" "MCF7: 27.1;OE19: 57.5;SK-BR-3: 24.1;T-47d: 22.2" "Not detected" "Not detected" "HPA041125, HPA053549" Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 690000 "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "HPA041125: AB_10794264, HPA053549: AB_2682184" "unprognostic (5.29e-2)" "unprognostic (2.71e-1)" "unprognostic (4.37e-2)" "prognostic favorable (3.48e-6)" "unprognostic (1.39e-3)" "unprognostic (1.94e-2)" "unprognostic (2.34e-3)" "unprognostic (4.13e-2)" "unprognostic (1.01e-1)" "unprognostic (3.45e-3)" "unprognostic (1.37e-1)" "unprognostic (1.47e-2)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.17e-1)" "unprognostic (1.04e-1)" "unprognostic (8.33e-2)" 2.5 13.2 0.0 3.9 0.0 4.6 33.1 0.0 0.1 33.0 0.0 13.6 11.5 0.6 1.5 25.3 4.4 34.4 9.0 0.0 0.0 2.6 8.2 3.3 0.3 0.0 0.8 10.3 46.6 30.4 6.0 4.8 0.1 89.1 17.8 0.0 63926.2 7.1 6.1 47.7 9.6 0.4 0.0 4.2 33.2 4.4 0.0 0.2 2.9 0.1 5.9 11.2 16.3 0.0 0.0 1.1 0.0 0.0 0.3 1.9 0.2 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.3 0.0 0.2 2.1 0.0 4.4 0.0 0.0 0.0 9.0 2.8 2.4 1.6 0.0 0.0 0.1 0.2 0.0 1.2 0.1 0.0 0.0 0.2 3.6 0.2 27.1 0.0 0.4 0.1 57.5 5.0 0.0 0.0 8.6 0.2 6.3 0.0 0.0 0.1 24.1 0.0 0.1 22.2 0.0 3.1 0.1 0.5 1.9 0.1 0.0 0.5 0.3 0.3 6.5 0.3 1.7 6.3 0.0 0.0 11.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.4 1.2 7.4 0.0 0.5 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 9.1 194.0 181.6 0.0 0.0 154.9 82.5 0.0 70.1 343.9 1.8 0.0 0.1 2.0 107.1 0.0 5.9 7.7 3.5 1.6 2.8 58.2 0.4 0.0 28.1 3.2 1.8 21.9 13.0 5.7 1.7 0.7 0.1 14.6 0.0 0.0 232.2 140.4 4.6 0.5 5.7 0.0 4.4 83.6 0.0 5.6 0.0 0.0 0.0 0.0 46.4 65.3 0.0 0.0 398.1 12.5 0.0 74.7 0.0 0.0 0.0 19.2 1.4 0.6 9.5 24.0 0.3 2.5 21.3 76.7 357.4 ZHX3 "KIAA0395, TIX1" ENSG00000174306 "Zinc fingers and homeoboxes 3" Q9H4I2 20 41178448-41317672 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 370.5;Early spermatids: 106.3;Excitatory neurons: 99.0;Inhibitory neurons: 96.5;Oligodendrocyte precursor cells: 139.7;Oligodendrocytes: 142.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046498 Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA046498: AB_2679676" "unprognostic (6.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.50e-2)" "unprognostic (2.29e-1)" "unprognostic (3.88e-1)" "unprognostic (3.42e-1)" "unprognostic (7.25e-3)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.53e-5)" "unprognostic (3.06e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (7.52e-4)" "prognostic unfavorable (1.84e-5)" 14.4 15.4 33.8 6.5 32.8 3.4 13.3 31.6 27.4 11.6 16.4 19.8 8.6 15.8 5.7 13.6 15.7 8.4 12.2 30.2 27.7 26.4 17.2 11.6 4.5 37.6 32.1 16.3 11.9 15.4 7.8 4.9 29.9 10.6 8.0 10.8 5.7 11.9 28.5 11.0 11.4 12.1 29.4 4.3 15.5 35.0 36.0 7.0 19.0 20.1 4.8 18.1 11.0 28.6 22.5 6.3 6.6 14.2 52.6 56.3 7.6 31.0 35.4 28.3 19.1 11.4 2.9 15.6 14.7 58.5 7.6 7.0 7.9 39.2 30.0 4.3 7.1 6.6 8.6 8.8 21.6 7.6 7.9 34.6 18.7 21.3 27.3 19.2 12.3 11.7 6.2 10.6 38.3 45.0 11.9 4.5 2.9 10.4 23.0 5.8 18.6 6.2 38.6 6.7 23.0 8.3 20.7 12.0 7.4 5.7 11.6 10.5 19.9 70.2 10.8 25.0 15.5 12.2 8.0 6.9 28.9 11.0 11.4 0.1 0.1 0.4 0.2 0.1 0.4 0.6 0.2 0.1 0.2 0.6 0.4 0.3 0.1 0.6 0.2 0.1 0.2 0.1 33.8 32.8 31.6 27.4 30.2 27.7 37.6 32.1 29.9 29.4 36.0 28.6 29.8 19.2 16.4 370.5 4.7 2.9 3.9 2.6 2.8 19.5 6.3 4.7 12.7 17.2 5.8 22.0 4.2 0.6 3.8 5.5 11.7 3.7 106.3 12.3 33.2 15.1 14.9 3.8 99.0 2.7 2.7 20.5 6.6 26.3 1.3 3.7 16.4 31.6 3.0 40.4 96.5 5.6 4.1 3.5 1.7 32.3 18.6 3.5 1.8 52.5 1.9 28.6 1.0 139.7 142.4 4.6 1.3 24.5 2.7 2.6 12.6 27.0 3.2 7.1 26.3 41.2 10.9 11.0 5.2 6.3 3.7 0.4 2.7 19.7 4.7 2.3 ZNF106 "SH3BP3, ZFP106, ZNF474" ENSG00000103994 "Zinc finger protein 106" Q9H2Y7 15 42412823-42491141 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 392.5;tongue: 465.5" "Cell type enriched" "Detected in all" 9 "Cardiomyocytes: 1836.4" "Cancer enhanced" "Detected in all" "melanoma: 29.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 161.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054267 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoli "Nucleoplasm, Cytosol" "HPA054267: AB_2682431" "unprognostic (2.15e-2)" "unprognostic (3.31e-1)" "unprognostic (7.10e-2)" "unprognostic (2.61e-2)" "unprognostic (4.01e-2)" "unprognostic (1.34e-1)" "unprognostic (9.32e-2)" "unprognostic (2.49e-1)" "unprognostic (3.96e-1)" "unprognostic (1.33e-2)" "unprognostic (2.27e-1)" "unprognostic (2.07e-1)" "unprognostic (1.76e-3)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (4.36e-1)" "unprognostic (4.09e-3)" 32.4 11.2 20.8 14.3 29.8 24.4 17.9 19.0 28.1 18.0 109.2 19.7 10.0 15.9 17.3 18.5 12.7 17.2 175.6 23.3 22.6 16.5 8.7 20.9 17.5 23.6 29.1 15.9 10.3 17.8 10.3 12.9 22.5 20.9 13.9 22.0 12.9 14.7 392.5 11.7 13.3 23.0 20.8 17.1 12.8 14.3 27.4 15.6 13.2 465.5 18.6 14.6 9.1 27.7 27.2 15.1 29.0 33.5 86.8 68.5 16.1 21.7 22.2 19.6 20.5 33.9 7.8 17.8 19.0 27.7 22.8 31.8 28.3 23.4 29.5 29.0 13.1 34.7 37.9 13.6 23.2 43.1 20.2 55.4 17.8 28.0 32.6 19.5 32.3 23.2 43.0 2.7 36.9 11.9 16.2 13.3 11.0 26.1 15.1 15.2 54.3 10.8 12.1 31.5 16.5 10.2 45.0 22.8 28.7 23.4 20.0 30.0 42.2 20.8 32.5 26.1 32.3 14.8 32.2 76.5 18.4 33.6 37.6 86.8 63.8 27.1 15.6 52.3 13.5 21.8 13.0 13.3 35.6 26.8 11.3 10.6 161.0 12.5 66.8 36.0 13.0 18.0 20.8 29.8 19.0 28.1 23.3 22.6 23.6 29.1 22.5 20.8 27.4 27.7 58.0 134.6 107.7 46.0 49.6 38.5 57.9 41.9 44.3 58.5 50.9 46.0 1836.4 62.9 57.0 29.5 95.9 37.9 67.2 31.7 41.1 43.2 197.2 75.2 67.1 69.9 40.2 50.5 73.3 42.4 39.3 141.7 31.1 37.5 44.9 49.5 62.8 40.1 53.5 35.3 62.9 32.6 32.6 132.7 43.4 105.2 37.6 89.8 65.8 47.8 124.3 53.6 66.9 31.2 34.2 65.7 26.9 92.6 50.7 74.8 39.7 41.5 161.1 79.9 46.0 151.2 70.0 62.3 38.1 49.8 29.8 30.6 46.0 85.9 36.6 68.2 ZNF117 "H-plk, HPF9" ENSG00000152926 "Zinc finger protein 117" Q03924 7 64971772-65006684 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 21.0;SuSa: 21.9;THP-1: 21.9" HPA031148 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nucleoli fibrillar center, Cytosol" "HPA031148: AB_2673759" "unprognostic (1.04e-1)" "unprognostic (3.04e-2)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.35e-2)" "unprognostic (1.45e-2)" "unprognostic (1.24e-1)" "unprognostic (6.13e-2)" "unprognostic (2.30e-1)" "unprognostic (3.35e-1)" "unprognostic (7.10e-2)" "prognostic unfavorable (2.17e-11)" "unprognostic (1.08e-1)" "unprognostic (9.19e-2)" "unprognostic (1.49e-2)" "unprognostic (1.21e-1)" 20.6 28.1 3.8 7.1 3.0 5.4 17.0 3.2 4.5 13.1 4.3 6.8 2.2 8.3 11.2 12.0 8.2 10.2 7.6 3.2 3.7 6.8 3.5 10.8 6.0 4.4 4.3 10.6 5.2 3.7 9.3 10.1 3.1 7.6 4.7 11.8 7.8 4.9 2.8 8.2 4.9 5.7 3.2 8.9 4.6 12.3 3.7 4.7 8.5 1.4 5.6 6.7 11.6 4.1 1.7 0.1 20.0 21.0 7.4 3.4 11.2 4.4 1.0 1.1 2.1 0.9 8.6 7.6 3.6 2.2 3.2 1.3 2.3 0.5 2.4 2.3 2.0 3.5 0.5 4.2 0.6 0.0 2.0 4.3 0.8 0.8 0.8 8.0 3.4 8.8 14.4 5.1 5.0 3.8 8.0 7.9 8.4 2.5 0.3 10.4 1.3 1.5 2.7 3.3 3.1 16.9 2.2 0.9 0.9 21.9 3.8 21.9 10.2 6.0 0.7 3.6 2.8 3.4 6.7 3.9 2.2 9.7 3.7 0.2 0.2 0.3 0.2 0.7 0.2 0.3 0.1 0.1 0.2 0.3 0.1 0.1 2.4 0.3 0.2 0.2 0.1 0.1 3.8 3.0 3.2 4.5 3.2 3.7 4.4 4.3 3.1 3.2 3.7 4.1 10.3 3.2 43.0 35.6 4.2 3.3 5.8 6.2 0.6 14.3 15.5 10.7 7.3 12.8 23.2 5.5 0.0 5.4 5.4 3.3 11.7 10.9 3.1 7.5 10.4 10.9 5.3 2.1 11.4 28.5 2.5 9.6 3.1 8.9 10.8 21.1 17.5 4.2 6.6 28.6 11.6 4.1 10.2 7.9 7.5 3.1 8.7 11.8 5.4 9.4 4.1 7.1 7.2 19.6 7.2 17.7 1.7 5.3 2.3 4.6 1.6 3.3 20.2 7.7 6.6 7.1 7.9 7.2 8.4 3.2 4.7 11.1 3.8 10.3 2.4 12.3 ZNF134 pHZ-15 ENSG00000213762 "Zinc finger protein 134" P52741 19 57614233-57624724 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA009064 Supported Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA009064: AB_1080668" "unprognostic (3.60e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.88e-1)" "unprognostic (4.29e-2)" "unprognostic (9.62e-2)" "prognostic unfavorable (5.21e-4)" "unprognostic (6.34e-2)" "unprognostic (1.35e-1)" "unprognostic (4.34e-2)" "unprognostic (1.48e-1)" "unprognostic (3.39e-2)" "unprognostic (1.17e-2)" "prognostic favorable (2.61e-4)" "unprognostic (1.56e-2)" "unprognostic (3.40e-1)" "unprognostic (2.52e-2)" "unprognostic (1.34e-1)" 4.6 5.4 4.9 4.7 5.2 12.5 7.5 8.7 5.3 5.7 4.0 6.5 3.5 5.5 6.0 5.3 6.5 4.5 6.0 4.9 5.5 5.6 4.9 5.8 7.5 3.9 4.0 7.6 3.8 12.0 5.7 7.9 3.7 7.3 4.5 10.6 5.4 8.3 6.3 7.1 4.9 6.0 3.6 7.1 6.0 6.6 5.5 11.1 8.3 7.2 8.5 6.1 4.1 4.7 2.5 6.6 15.5 8.4 6.8 9.1 7.7 6.8 11.1 9.8 4.9 2.2 2.9 5.0 4.7 8.5 7.5 2.1 7.2 12.6 16.8 0.1 33.2 15.8 7.0 6.2 9.9 10.6 11.2 12.3 12.1 7.4 16.7 12.9 6.6 8.2 2.1 5.7 14.8 3.7 21.0 4.4 21.8 1.6 13.6 12.2 22.5 7.9 7.3 21.5 12.4 14.5 11.3 4.9 7.2 17.0 6.9 8.4 8.7 14.7 6.3 3.5 9.0 15.3 21.8 6.9 7.7 1.8 9.9 2.3 4.2 7.4 6.3 3.0 8.3 9.5 6.5 6.7 4.6 8.3 7.5 7.5 3.4 11.9 3.4 3.5 4.4 5.5 4.9 5.2 8.7 5.3 4.9 5.5 3.9 4.0 3.7 3.6 5.5 4.7 6.0 9.6 4.1 1.0 14.4 5.4 12.7 4.4 8.6 8.4 9.8 8.0 11.2 11.5 5.6 3.7 12.5 8.2 11.1 1.2 7.9 7.8 1.7 6.0 7.8 8.3 1.2 13.0 1.0 3.7 4.3 6.2 1.1 7.3 6.3 10.6 9.7 4.1 5.3 8.4 0.9 4.0 6.1 5.1 3.2 1.5 7.2 4.4 3.6 0.0 7.0 11.3 9.2 1.0 1.6 3.8 2.6 14.7 5.0 9.3 2.8 4.6 5.1 11.9 6.6 6.6 8.5 2.2 15.2 6.7 7.7 16.3 8.8 8.0 3.6 13.8 ZNF16 KOX9 ENSG00000170631 "Zinc finger protein 16" P17020 8 144930358-144950888 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035782, HPA061835" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 15: NK-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Nucleoli Nucleoplasm "HPA035782: AB_10603243, HPA061835: AB_2684621" "unprognostic (4.11e-2)" "unprognostic (1.51e-2)" "unprognostic (6.87e-2)" "unprognostic (2.45e-1)" "unprognostic (2.69e-1)" "prognostic favorable (2.39e-4)" "unprognostic (7.53e-3)" "unprognostic (1.10e-1)" "unprognostic (1.24e-1)" "unprognostic (8.50e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.70e-2)" "unprognostic (2.96e-1)" "unprognostic (9.75e-2)" "unprognostic (4.17e-3)" 4.6 3.6 4.6 2.4 4.7 2.6 6.3 4.4 5.0 6.0 5.9 6.5 4.7 6.2 6.9 5.9 7.1 5.7 4.4 4.5 4.4 5.3 3.9 3.7 3.2 4.2 4.2 11.0 7.5 8.6 4.0 3.9 4.3 5.4 4.7 5.1 4.6 5.6 8.3 9.3 4.8 5.5 4.5 3.4 5.0 7.5 4.8 4.4 7.0 8.3 3.9 5.7 6.0 4.6 4.5 3.9 7.7 4.2 6.4 9.0 5.5 4.0 8.9 8.0 7.2 3.1 4.5 7.1 5.2 5.2 4.3 3.5 5.4 8.9 7.2 3.1 4.5 8.2 4.4 4.5 10.7 3.0 4.6 10.9 8.8 5.1 13.2 7.9 4.4 5.3 5.7 4.7 6.4 6.2 6.1 3.0 4.7 6.9 8.8 7.5 4.5 4.5 6.8 6.7 6.4 4.7 8.5 5.1 6.9 5.8 9.5 5.6 4.7 3.6 7.5 4.3 4.5 3.4 3.1 6.4 4.1 4.0 5.8 2.6 3.0 2.2 4.9 2.9 5.6 2.8 3.8 4.5 4.8 4.4 3.8 3.5 0.4 9.2 3.0 2.5 5.8 3.2 4.6 4.7 4.4 5.0 4.5 4.4 4.2 4.2 4.3 4.5 4.8 4.6 3.6 3.2 4.4 4.9 3.4 2.7 6.9 6.8 5.2 11.4 4.3 2.9 3.7 5.7 3.1 9.2 12.5 5.9 7.0 3.2 1.9 7.3 10.3 2.0 3.5 3.7 4.2 3.0 6.8 4.4 3.6 3.8 5.1 3.9 7.0 9.4 5.0 4.5 3.6 6.7 6.3 5.6 6.1 3.5 2.4 3.7 6.2 2.1 1.8 6.5 5.4 6.2 7.2 6.6 7.2 3.6 4.9 6.4 3.2 4.2 10.6 4.8 3.4 25.1 0.0 3.4 4.0 13.6 18.1 4.5 4.5 5.5 5.1 6.6 5.4 5.5 ZNF22 "HKR-T1, KOX15, Zfp422, ZNF422" ENSG00000165512 "Zinc finger protein 22" P17026 10 45000923-45005326 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 184.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016736, HPA054893" Approved Enhanced Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA016736: AB_1859133, HPA054893: AB_2682632" "unprognostic (2.87e-2)" "unprognostic (1.10e-1)" "unprognostic (2.65e-1)" "unprognostic (5.77e-2)" "unprognostic (3.50e-3)" "unprognostic (3.42e-2)" "unprognostic (4.77e-2)" "unprognostic (2.01e-1)" "unprognostic (1.01e-3)" "unprognostic (9.31e-3)" "unprognostic (2.94e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.11e-5)" "prognostic unfavorable (8.06e-4)" "unprognostic (1.39e-1)" "unprognostic (9.96e-2)" "unprognostic (4.58e-2)" 28.3 13.5 19.8 21.9 21.3 25.7 41.1 20.5 26.1 22.8 18.1 21.0 18.9 30.6 23.5 10.9 25.7 17.6 23.9 19.1 21.0 25.2 38.7 23.1 36.1 25.1 20.7 35.8 39.6 13.3 8.6 40.0 21.5 22.8 21.6 19.2 22.7 19.6 21.1 8.4 18.2 23.9 21.4 27.1 22.8 9.0 20.9 70.4 23.9 25.7 35.1 18.1 10.9 22.9 46.7 7.4 63.3 39.3 32.1 23.2 0.5 21.6 44.5 54.7 58.8 25.5 38.6 48.4 33.5 32.5 12.0 7.8 62.1 23.2 77.3 30.3 1.1 50.3 11.3 0.3 68.8 98.5 17.0 41.6 33.3 22.3 0.9 0.5 87.7 127.8 67.8 84.9 43.7 1.4 184.0 148.5 38.0 26.8 12.9 133.8 87.8 69.4 43.0 39.2 60.5 52.7 19.3 38.8 32.3 57.5 8.4 96.7 48.4 39.2 72.2 27.2 73.3 48.0 51.0 46.4 24.4 3.6 42.6 28.2 28.1 37.6 51.7 27.5 62.5 42.2 33.6 53.8 37.8 54.4 45.3 56.6 2.9 70.8 18.3 64.7 21.1 38.1 19.8 21.3 20.5 26.1 19.1 21.0 25.1 20.7 21.5 21.4 20.9 22.9 69.3 28.9 27.4 5.9 45.7 19.2 65.5 34.1 42.1 33.6 51.2 68.6 9.9 68.6 25.2 33.1 10.4 71.7 48.0 7.0 56.7 58.7 6.3 22.1 48.7 72.9 40.0 67.5 5.0 43.3 55.8 49.5 21.4 25.4 33.5 59.1 91.8 58.6 49.3 38.7 7.6 37.2 38.7 28.7 28.4 3.6 44.4 32.7 19.6 4.7 61.4 57.2 89.6 7.5 11.3 35.7 15.1 51.1 31.9 57.9 6.9 54.6 28.4 32.7 32.9 77.1 48.4 40.1 37.1 23.9 13.2 53.2 36.4 58.7 34.7 27.6 ZNF250 "MGC9718, ZFP647, ZNF647" ENSG00000196150 "Zinc finger protein 250" P15622 8 144876497-144902168 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020853 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" Cytosol "HPA020853: AB_1859152" "unprognostic (1.16e-3)" "unprognostic (9.56e-2)" "unprognostic (2.63e-1)" "unprognostic (2.60e-3)" "unprognostic (1.03e-1)" "unprognostic (5.95e-3)" "unprognostic (3.73e-3)" "unprognostic (2.72e-2)" "unprognostic (6.27e-2)" "unprognostic (7.37e-2)" "unprognostic (4.94e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.43e-7)" "unprognostic (2.23e-1)" "unprognostic (6.79e-2)" "unprognostic (5.82e-2)" "prognostic favorable (8.26e-4)" 4.7 3.9 3.2 3.3 3.2 2.9 5.6 10.5 4.7 9.7 2.3 6.9 4.8 7.4 2.8 6.4 7.6 3.3 4.9 2.4 4.5 7.6 4.0 5.1 3.0 3.0 3.2 9.7 4.9 6.0 7.3 5.5 3.3 7.5 3.6 7.9 6.0 5.2 4.8 10.9 5.2 4.2 1.5 5.5 4.9 4.5 3.3 4.5 10.0 5.8 3.3 6.3 8.6 3.4 5.1 2.9 13.4 11.1 6.8 5.9 4.3 5.6 6.4 9.4 7.7 2.4 3.9 12.0 9.8 6.5 3.8 6.6 5.3 4.8 6.0 3.8 7.8 10.8 14.9 3.5 2.0 1.8 3.6 3.9 6.5 5.6 4.5 7.2 3.9 7.1 8.6 11.5 7.9 6.8 12.6 4.1 4.0 6.0 12.5 14.4 5.9 5.0 7.8 3.7 13.2 10.1 11.8 4.4 5.3 5.3 6.3 6.1 5.1 9.2 8.8 7.3 5.3 5.6 5.1 8.0 4.7 6.2 4.1 3.2 5.1 5.8 10.5 2.7 8.1 10.3 7.7 5.8 6.6 9.7 8.9 7.3 2.9 6.0 3.7 2.6 11.7 4.5 3.2 3.2 10.5 4.7 2.4 4.5 3.0 3.2 3.3 1.5 3.3 3.4 5.8 12.8 3.0 10.7 10.7 5.5 3.2 7.5 10.2 8.4 4.3 6.6 4.3 1.5 3.9 5.5 0.0 2.3 18.6 2.4 3.9 7.5 7.4 5.1 6.0 5.5 4.2 1.7 11.9 1.9 1.3 5.2 2.6 4.9 2.5 6.3 5.0 2.1 1.7 8.4 17.5 1.9 12.2 2.2 8.0 3.0 4.1 3.0 5.4 4.7 2.0 3.3 5.2 11.1 7.8 2.6 1.0 5.3 8.2 3.3 3.7 3.4 5.0 9.9 13.1 4.1 6.1 14.3 8.7 4.4 5.5 1.9 10.9 4.9 3.4 2.3 ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 19.0;Cone photoreceptor cells: 31.3;Endothelial cells: 18.3;Langerhans cells: 9.3;Microglial cells: 54.4;monocytes: 14.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.4" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.3;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526, HPA074074" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA023128: AB_1859223, HPA023526: AB_1859224, HPA074074: " "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)" 5.8 0.8 6.1 3.4 5.0 0.1 3.2 4.5 5.6 2.8 2.4 1.4 1.5 3.1 0.7 1.8 2.4 2.3 3.8 4.1 4.6 2.1 1.0 2.6 5.0 5.8 5.5 0.8 0.7 1.1 0.4 8.9 6.0 0.9 1.5 0.5 0.8 1.5 5.0 2.2 1.9 3.9 4.1 6.4 1.4 0.5 7.1 3.1 2.2 5.6 4.0 1.7 1.0 4.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.5 6.1 5.0 4.5 5.6 4.1 4.6 5.8 5.5 6.0 4.1 7.1 4.5 19.0 0.0 0.6 0.0 0.1 0.5 0.4 0.0 0.6 0.4 0.1 0.3 1.6 0.0 0.6 0.0 31.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.8 0.4 0.5 0.0 0.3 0.0 0.0 4.6 9.3 0.5 0.3 2.4 0.0 54.4 14.5 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.7 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 0.0 ZNF367 FLJ33970 ENSG00000165244 "Zinc finger protein 367" Q7RTV3 9 96385941-96418370 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA015319, HPA015785" Uncertain Supported Nucleoplasm NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA015319: AB_2669185, HPA015785: AB_2217750" "unprognostic (5.91e-2)" "unprognostic (2.78e-3)" "unprognostic (2.17e-2)" "unprognostic (1.11e-2)" "unprognostic (2.36e-1)" "unprognostic (4.57e-3)" "unprognostic (7.76e-3)" "unprognostic (1.60e-3)" "unprognostic (4.35e-2)" "unprognostic (3.01e-1)" "unprognostic (3.78e-3)" "unprognostic (2.71e-2)" "unprognostic (4.88e-3)" "unprognostic (3.23e-3)" "unprognostic (1.72e-1)" "prognostic favorable (2.34e-4)" "unprognostic (2.28e-1)" 1.4 0.6 0.7 3.7 1.3 26.1 1.7 1.4 1.3 1.1 0.2 3.0 2.9 1.1 0.1 2.4 0.7 1.0 2.1 0.7 1.0 3.0 10.8 1.1 4.6 1.5 1.4 1.0 1.4 1.6 0.3 1.9 1.4 1.2 3.3 1.3 0.7 0.4 1.5 3.5 3.0 2.4 0.9 1.3 2.1 6.1 1.3 8.7 1.1 2.7 4.7 1.5 1.2 2.7 25.4 10.3 9.9 8.9 3.8 5.3 13.4 34.6 20.4 16.9 20.0 6.4 17.5 19.2 14.4 16.5 12.6 30.5 11.6 12.6 19.9 21.2 10.0 14.0 19.1 5.3 0.0 19.8 16.5 0.9 0.8 13.7 6.9 3.7 6.3 13.3 13.0 45.4 21.7 16.9 30.4 16.1 6.7 27.9 16.7 15.3 49.9 11.7 4.9 16.8 17.4 12.0 15.3 18.1 10.6 8.0 9.4 17.3 5.7 27.6 15.8 25.6 26.6 17.6 32.0 7.8 16.7 17.0 23.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.7 1.3 1.4 1.3 0.7 1.0 1.5 1.4 1.4 0.9 1.3 2.7 1.1 0.0 0.0 2.9 3.8 9.9 1.3 0.4 10.8 0.7 2.2 2.3 2.6 0.0 0.9 0.0 0.0 3.2 2.5 2.4 0.0 0.5 0.7 0.6 1.1 2.0 0.0 22.3 5.1 1.2 4.2 1.7 2.6 1.8 0.0 4.7 1.1 3.8 1.9 0.0 5.3 3.6 0.0 2.1 2.6 0.8 0.6 8.3 3.6 2.8 0.1 0.6 1.0 3.0 7.9 0.7 0.5 0.7 9.6 0.6 0.9 2.5 0.0 1.5 6.6 2.0 3.6 10.3 1.7 10.9 6.5 0.8 5.0 0.3 5.6 1.1 ZNF385A "DKFZp586G1122, Hzf, ZFP385, ZNF385" ENSG00000161642 "Zinc finger protein 385A" Q96PM9 12 54369133-54391298 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation, Translation regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.3;retina: 250.6;skin 1: 159.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.8;Cone photoreceptor cells: 171.0;Horizontal cells: 144.7;Muller glia cells: 142.6;Rod photoreceptor cells: 209.7;Syncytiotrophoblasts: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 29.2;intermediate monocyte: 32.8;myeloid DC: 31.9;non-classical monocyte: 25.7" "Group enriched" "Detected in many" 11 "dendritic cells: 31.9;monocytes: 32.8" "Cell line enhanced" "Detected in many" "HaCaT: 89.5;HBEC3-KT: 85.7;HEL: 109.5;hTCEpi: 94.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039799 Supported Nucleoplasm,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Cytosol" "HPA039799: AB_10795117" "unprognostic (8.56e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (6.70e-2)" "unprognostic (1.07e-2)" "unprognostic (1.79e-3)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (9.75e-5)" "unprognostic (1.00e-1)" "unprognostic (3.68e-2)" "unprognostic (2.43e-1)" "unprognostic (6.07e-3)" 43.3 10.1 76.8 28.6 87.9 32.8 22.2 96.9 86.3 29.2 57.7 13.8 7.2 7.6 16.6 99.5 9.7 14.2 13.7 60.2 89.8 10.2 6.4 19.1 15.3 105.5 111.9 5.3 3.3 26.6 26.7 19.4 93.9 34.9 8.0 250.6 28.1 15.0 21.9 159.8 15.8 14.2 95.1 24.8 10.4 2.4 159.3 12.1 40.8 23.3 20.3 38.8 55.8 65.1 2.5 10.7 15.9 20.0 17.9 12.0 43.6 2.1 8.1 8.3 7.1 21.8 7.8 5.9 7.2 4.4 6.7 89.5 6.1 85.7 2.8 5.8 8.5 109.5 6.6 4.3 8.0 1.6 73.4 10.7 94.8 9.3 23.5 20.3 5.2 15.0 53.6 0.5 3.8 49.9 5.4 15.9 9.2 10.1 8.3 19.5 1.3 21.7 6.5 71.0 7.0 31.6 0.8 59.7 4.5 18.3 71.0 45.5 5.3 4.4 10.2 5.4 5.6 1.7 0.5 5.3 18.6 5.0 11.8 3.0 29.2 0.0 0.0 32.8 0.0 1.3 0.0 0.0 31.9 1.3 0.0 0.4 2.2 0.1 25.7 3.0 0.1 16.5 76.8 87.9 96.9 86.3 60.2 89.8 105.5 111.9 93.9 95.1 159.3 65.1 8.3 0.0 0.0 12.1 7.3 36.2 21.3 76.5 49.5 212.8 16.7 13.8 3.2 1.5 20.4 9.2 171.0 63.9 2.5 0.2 9.8 3.4 0.5 13.3 9.8 8.8 4.8 9.2 5.4 0.6 9.4 29.6 3.6 2.2 1.3 4.8 4.6 1.3 56.4 144.7 13.5 0.1 12.2 71.6 54.7 0.5 14.9 78.0 8.8 6.5 49.4 142.6 3.1 3.5 0.9 1.8 0.1 9.1 2.0 13.1 0.0 2.8 12.1 209.7 0.0 4.0 12.3 2.6 3.6 68.3 66.1 108.9 2.2 0.2 0.1 29.7 ZNF385B "FLJ25270, ZNF533" ENSG00000144331 "Zinc finger protein 385B" Q569K4 2 179441982-179861612 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 88.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 124.2;Bipolar cells: 220.1;Excitatory neurons: 566.5;Inhibitory neurons: 393.1;Rod photoreceptor cells: 133.7" "Cancer enhanced" "Detected in many" "prostate cancer: 6.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 17.6;HAP1: 31.9;U-698: 91.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046086 Approved "Nucleoli fibrillar center" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "HPA046086: AB_2679532" "prognostic favorable (4.86e-8)" "unprognostic (8.05e-3)" "unprognostic (1.14e-1)" "unprognostic (3.91e-2)" "unprognostic (3.49e-1)" "unprognostic (1.51e-2)" "unprognostic (3.49e-3)" "unprognostic (1.14e-1)" "unprognostic (8.99e-3)" "unprognostic (3.56e-2)" "unprognostic (4.59e-2)" "unprognostic (2.69e-1)" "prognostic favorable (1.04e-9)" "unprognostic (7.76e-2)" "unprognostic (2.94e-2)" "unprognostic (3.35e-2)" "unprognostic (1.20e-3)" 2.3 5.2 4.1 0.3 25.4 0.4 6.9 27.3 17.4 1.6 0.0 2.4 0.3 1.5 3.8 1.1 1.1 0.7 24.1 6.9 1.9 8.5 19.1 18.4 1.6 9.6 3.0 15.2 0.3 0.0 1.0 2.2 10.8 12.6 0.7 88.7 1.2 0.5 17.1 1.6 0.8 0.4 0.0 0.5 14.2 10.3 6.8 0.5 1.2 10.9 0.6 1.5 2.2 9.5 0.0 0.0 7.3 0.3 0.1 0.3 0.1 0.0 0.0 0.4 0.8 0.0 0.0 17.6 0.1 0.0 5.9 0.0 31.9 0.0 0.4 0.0 4.3 0.2 0.7 1.2 0.0 0.0 0.0 3.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.3 0.1 0.1 1.3 0.0 2.0 0.0 1.3 1.3 1.8 0.0 0.7 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.3 2.3 0.3 1.5 0.0 0.0 91.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 25.4 27.3 17.4 6.9 1.9 9.6 3.0 10.8 0.0 6.8 9.5 1.0 28.9 124.2 12.1 0.0 3.4 0.7 0.0 0.0 220.1 5.1 2.2 32.4 5.7 1.3 0.0 54.2 0.0 0.0 0.3 82.2 0.0 58.4 1.0 0.1 0.5 1.8 0.0 566.5 0.0 0.0 6.4 3.1 1.7 1.3 19.6 1.4 14.3 0.3 1.7 393.1 0.0 0.0 0.0 0.3 29.2 0.6 0.5 1.8 89.0 0.0 6.4 0.0 20.1 10.7 0.1 0.0 0.4 0.1 4.9 0.0 24.5 1.5 133.7 0.0 5.2 1.6 6.2 1.8 0.1 0.9 0.1 0.3 3.3 0.1 0.9 ZNF385D "FLJ22419, ZNF659" ENSG00000151789 "Zinc finger protein 385D" Q9H6B1 3 21412218-22373321 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 44.0;testis: 15.1" "Cell type enriched" "Detected in many" 5 "Inhibitory neurons: 1766.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 8 "cerebellum: 44.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.8;hTERT-RPE1: 5.4;LHCN-M2: 5.3;PC-3: 5.3;RPTEC TERT1: 15.1;U-87 MG: 21.1" "Low region specificity" "Detected in all" HPA036190 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA036190: AB_10602355" "unprognostic (4.07e-2)" "unprognostic (1.26e-1)" "unprognostic (5.44e-2)" "unprognostic (3.23e-2)" "unprognostic (1.64e-1)" "unprognostic (1.74e-1)" "unprognostic (8.20e-2)" "unprognostic (6.60e-2)" "unprognostic (7.84e-2)" "unprognostic (3.73e-1)" "unprognostic (2.35e-1)" "unprognostic (9.01e-2)" "unprognostic (3.49e-7)" "unprognostic (8.70e-3)" "unprognostic (5.38e-2)" "unprognostic (7.76e-3)" "unprognostic (2.15e-5)" 3.8 0.2 2.6 1.4 4.5 0.3 2.2 44.0 5.4 1.8 0.0 0.8 0.3 1.1 0.5 2.0 0.7 2.7 1.8 1.7 2.5 1.4 0.1 0.6 0.8 3.3 4.5 0.6 0.6 0.2 0.1 0.0 3.6 1.3 0.5 7.3 0.7 1.1 1.0 0.7 0.5 1.7 1.5 0.3 0.4 15.1 3.1 0.7 0.5 3.3 1.0 2.7 1.2 5.3 0.0 0.0 0.3 0.0 2.0 4.3 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.2 0.0 5.4 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.5 0.0 5.3 0.0 0.0 0.0 15.1 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.1 0.0 0.0 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 2.6 4.5 44.0 5.4 1.7 2.5 3.3 4.5 3.6 1.5 3.1 5.3 82.2 12.8 13.4 17.3 1.4 9.7 0.7 6.2 1.8 58.8 1.5 6.3 3.6 1.5 19.2 1.8 8.4 0.3 1.4 0.9 27.4 0.6 174.9 0.2 1.9 89.0 0.0 12.6 267.5 0.7 0.2 20.5 0.0 0.3 5.1 1.8 2.2 5.8 0.4 323.0 1766.6 0.7 0.0 0.0 14.0 274.5 16.8 4.9 12.4 64.6 0.6 114.3 1.0 159.3 12.7 1.4 0.6 13.5 0.3 1.7 2.3 6.6 4.4 31.0 13.1 22.0 20.2 50.4 2.0 0.6 7.7 0.1 1.5 34.3 0.7 1.0 ZNF398 "KIAA1339, P51, P71, ZER6" ENSG00000197024 "Zinc finger protein 398" Q8TD17 7 149126416-149183042 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 32.3;Inhibitory neurons: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "NTERA-2: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073151 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear membrane" "HPA073151: " "unprognostic (4.11e-1)" "unprognostic (8.56e-2)" "unprognostic (3.90e-2)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (6.65e-3)" "unprognostic (2.94e-3)" "unprognostic (2.27e-2)" "unprognostic (3.64e-3)" "unprognostic (1.43e-1)" "unprognostic (7.52e-2)" "unprognostic (2.75e-2)" "unprognostic (1.45e-1)" "unprognostic (3.97e-2)" "unprognostic (9.27e-2)" "unprognostic (9.17e-2)" "unprognostic (1.89e-1)" 3.9 3.3 1.6 3.6 1.8 7.6 4.4 6.3 3.7 4.9 0.6 4.4 3.7 4.1 4.3 6.4 4.3 3.0 3.3 1.6 2.2 3.5 3.6 3.8 4.7 0.1 0.4 4.4 4.5 5.0 4.9 3.8 0.2 4.8 3.6 7.6 4.8 5.1 4.4 6.8 3.7 4.0 0.0 4.5 4.5 8.5 1.8 5.3 3.6 4.5 5.6 4.8 5.0 2.5 9.8 9.5 7.1 13.8 10.4 7.4 8.4 5.8 8.6 7.3 8.2 7.9 5.0 12.5 6.8 10.6 6.5 8.0 12.0 8.2 5.3 7.3 14.4 8.3 7.2 5.3 7.3 9.8 8.1 8.3 12.1 8.2 8.4 5.4 5.2 4.9 11.9 4.7 8.3 13.9 13.6 10.3 47.1 9.4 8.9 10.3 7.9 9.1 5.7 19.0 9.8 10.9 9.2 11.2 5.7 7.7 6.8 10.6 6.2 7.4 1.9 13.3 7.6 12.7 6.6 9.6 9.6 8.0 7.4 2.4 0.6 2.3 1.1 0.7 1.4 1.0 0.8 1.2 0.5 0.8 1.2 1.3 1.2 0.7 0.6 0.7 1.1 0.4 1.6 1.8 6.3 3.7 1.6 2.2 0.1 0.4 0.2 0.0 1.8 2.5 3.9 6.4 4.6 19.2 6.6 7.8 4.5 4.0 5.7 8.8 5.6 3.7 5.9 0.0 5.5 5.5 6.2 4.2 7.7 4.4 0.0 3.9 23.5 7.0 8.6 5.9 1.8 8.6 32.3 2.8 4.9 5.1 12.2 7.5 4.5 7.1 3.9 2.8 3.7 3.3 31.3 3.7 2.0 5.0 3.3 25.2 7.2 3.9 8.8 21.5 4.8 4.5 3.1 20.6 28.6 4.6 2.1 9.1 10.9 6.6 3.8 3.1 6.9 11.6 0.0 6.4 4.5 21.4 13.5 10.1 8.5 3.1 5.2 4.7 3.8 9.9 ZNF410 "APA-1, APA1" ENSG00000119725 "Zinc finger protein 410" Q86VK4 14 73886617-73932521 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 27.7;Excitatory neurons: 22.7;Inhibitory neurons: 23.8;Oligodendrocytes: 31.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002871 Approved "Nuclear bodies" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Nuclear bodies" "HPA002871: AB_1080712" "unprognostic (5.84e-2)" "unprognostic (5.04e-2)" "unprognostic (9.29e-2)" "unprognostic (6.36e-3)" "unprognostic (5.86e-4)" "unprognostic (4.91e-2)" "unprognostic (2.83e-3)" "unprognostic (2.10e-2)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (1.86e-3)" "unprognostic (1.29e-2)" "unprognostic (3.73e-2)" "unprognostic (2.79e-2)" "unprognostic (2.46e-1)" "unprognostic (3.21e-2)" "unprognostic (1.19e-1)" 29.0 33.0 26.8 18.7 30.4 57.7 29.4 30.9 33.9 30.0 28.9 30.6 19.0 27.5 43.7 33.4 28.1 22.6 21.0 26.3 28.0 33.0 28.8 27.6 25.6 29.1 27.5 38.7 20.6 27.1 27.0 32.2 29.6 29.5 24.4 22.8 24.4 27.3 21.1 37.6 25.2 28.4 26.7 26.1 25.7 44.7 28.3 29.9 24.6 18.3 30.7 29.1 28.7 37.0 46.7 35.8 42.4 45.2 44.8 39.8 52.4 51.4 56.9 88.2 82.0 37.6 40.1 38.4 21.7 65.7 28.2 42.1 42.9 52.8 83.2 56.2 26.9 36.2 31.6 29.9 67.4 30.6 45.6 37.0 72.4 44.5 83.1 39.5 47.5 43.9 38.2 33.0 43.3 88.6 45.8 51.2 15.5 56.3 41.7 40.7 48.5 24.7 57.0 43.7 39.0 50.3 57.2 52.5 54.6 35.5 48.3 52.2 30.7 62.7 59.0 37.1 47.2 45.2 83.4 48.0 40.1 34.1 53.7 65.9 45.3 74.8 47.5 43.1 51.9 37.7 49.0 49.0 45.6 43.0 42.3 43.5 34.4 60.5 50.1 30.8 46.7 55.9 26.8 30.4 30.9 33.9 26.3 28.0 29.1 27.5 29.6 26.7 28.3 37.0 4.3 0.0 3.1 27.7 10.8 0.6 1.5 1.0 10.8 1.5 2.2 1.7 1.1 0.0 2.9 0.0 4.2 1.8 5.0 1.7 0.0 1.0 3.8 4.7 5.6 2.6 0.0 5.9 22.7 0.9 1.5 5.3 10.7 6.7 10.8 2.9 1.8 0.4 1.2 1.7 23.8 1.1 0.0 2.2 3.1 1.1 1.2 5.4 1.8 18.7 1.1 2.4 2.1 18.1 31.0 1.3 1.4 0.4 13.4 1.0 2.4 0.7 0.2 4.7 0.0 4.0 5.1 3.3 1.9 10.1 1.1 2.6 10.5 4.1 0.8 1.4 ZNF416 FLJ20557 ENSG00000083817 "Zinc finger protein 416" Q9BWM5 19 57571566-57578911 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA063318 Approved "Nuclear bodies,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nuclear bodies" "HPA063318: AB_2684983" "unprognostic (1.40e-1)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.99e-2)" "unprognostic (1.14e-2)" "unprognostic (7.57e-3)" "unprognostic (3.66e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (8.54e-2)" "unprognostic (6.62e-3)" "unprognostic (5.37e-2)" "prognostic favorable (1.20e-5)" "unprognostic (1.31e-1)" "unprognostic (2.62e-1)" "unprognostic (8.03e-3)" "unprognostic (1.70e-1)" 2.2 2.2 2.6 1.6 3.0 2.6 3.7 4.3 3.7 2.7 2.2 2.3 1.4 2.3 3.9 3.2 3.4 1.8 2.7 2.7 2.5 2.6 2.0 2.5 2.8 2.0 2.2 4.4 1.4 4.4 2.0 2.9 2.0 2.7 2.1 3.7 2.2 3.1 2.6 5.1 1.7 2.8 2.2 2.8 2.1 4.2 2.6 4.0 3.6 3.0 4.1 2.4 2.4 2.9 3.2 3.1 6.5 5.2 3.9 5.6 4.3 3.2 5.8 6.2 4.0 2.2 1.7 2.2 2.3 4.1 4.5 1.2 3.8 5.5 7.6 3.5 15.5 5.3 3.5 1.8 7.0 4.7 3.3 5.6 5.6 3.9 8.2 4.9 4.3 5.3 0.7 1.7 8.4 1.3 9.9 2.2 7.7 3.8 5.7 4.9 9.7 4.8 4.3 6.8 4.7 5.3 5.8 3.0 2.9 7.3 2.7 5.6 3.2 6.7 3.2 2.2 4.8 5.4 9.5 5.9 1.5 3.1 4.1 1.1 2.6 1.9 4.3 1.9 7.7 6.6 5.9 6.3 4.1 10.4 8.0 5.8 0.8 9.0 1.7 3.7 2.9 3.7 2.6 3.0 4.3 3.7 2.7 2.5 2.0 2.2 2.0 2.2 2.6 2.9 1.1 0.0 0.5 1.3 2.9 1.7 1.6 1.6 1.2 3.5 1.6 1.8 1.8 1.5 1.6 0.0 0.0 2.1 1.0 0.6 3.9 2.8 5.0 0.9 0.9 1.8 0.0 3.6 1.5 0.9 0.8 1.1 1.5 1.1 2.5 2.6 0.7 1.2 1.7 8.4 1.4 1.1 0.0 1.0 0.6 2.0 0.9 0.6 0.0 1.0 0.5 3.2 3.1 3.0 0.2 1.4 1.2 0.7 0.8 1.3 1.1 1.3 0.6 2.8 6.6 1.5 1.2 3.1 4.1 1.3 2.4 1.9 1.3 2.4 0.9 2.2 ZNF43 "HTF6, KOX27, ZNF39L1" ENSG00000198521 "Zinc finger protein 43" P17038 19 21804946-21852125 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 52.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 37.8" HPA050271 Uncertain NA NA "Cluster 30: Non-specific - Translation" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA050271: AB_2681070" "unprognostic (9.25e-3)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (2.50e-2)" "unprognostic (1.25e-1)" "unprognostic (4.16e-3)" "unprognostic (3.61e-2)" "unprognostic (2.47e-3)" "unprognostic (4.45e-3)" "prognostic favorable (3.16e-5)" "unprognostic (2.73e-2)" "unprognostic (1.01e-1)" "unprognostic (3.22e-1)" "unprognostic (1.75e-1)" "unprognostic (1.50e-1)" "unprognostic (3.37e-3)" "unprognostic (1.43e-3)" 3.9 4.0 1.6 5.5 4.1 10.7 7.8 10.6 3.0 4.9 1.1 4.4 3.6 6.3 4.6 3.6 6.8 4.0 4.5 1.5 5.2 5.0 1.4 4.2 8.4 2.9 1.9 11.2 3.0 6.7 2.6 4.8 3.2 7.2 5.3 6.7 3.5 4.9 3.1 7.3 4.2 4.4 0.8 6.6 4.8 8.7 2.9 10.1 8.7 4.1 6.8 3.6 3.1 7.7 0.4 3.7 25.0 19.8 2.7 5.9 10.4 6.6 2.7 8.3 11.4 0.3 3.8 5.9 7.5 4.2 7.7 0.5 0.3 0.7 13.8 0.8 6.5 0.3 1.6 2.9 1.3 0.2 7.2 5.6 0.9 8.9 0.4 2.1 1.9 21.8 0.4 1.1 6.3 4.3 37.8 9.1 18.0 0.5 5.4 22.0 9.8 6.6 5.4 18.9 16.7 12.6 0.1 0.1 2.2 11.3 9.6 5.1 0.4 0.7 0.8 6.0 7.0 1.5 11.3 10.2 0.3 0.8 0.8 30.7 4.5 6.2 8.8 4.6 8.4 18.8 11.5 9.9 4.6 19.1 18.6 12.7 4.5 9.0 4.0 8.5 8.1 3.9 1.6 4.1 10.6 3.0 1.5 5.2 2.9 1.9 3.2 0.8 2.9 7.7 17.0 12.8 15.1 19.2 14.4 2.0 8.1 1.4 2.8 16.0 10.6 12.2 13.2 8.6 9.9 3.7 10.4 9.4 10.6 3.7 17.6 11.0 36.3 11.6 13.6 16.0 11.4 16.2 9.5 9.4 7.6 12.8 5.1 16.6 16.4 52.0 16.8 0.4 4.8 8.4 14.1 4.2 6.1 4.4 4.4 9.8 14.0 6.6 1.8 18.7 6.5 12.5 20.6 26.7 23.1 7.6 4.0 9.4 7.7 8.8 2.4 7.4 6.6 9.6 6.6 13.8 13.3 21.3 15.7 3.3 2.0 5.9 10.8 41.0 7.1 4.4 ZNF496 "MGC15548, ZKSCAN17, ZSCAN49" ENSG00000162714 "Zinc finger protein 496" Q96IT1 1 247297412-247331846 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 40.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025824 Approved Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA025824: " "unprognostic (1.88e-3)" "unprognostic (3.31e-2)" "unprognostic (2.48e-2)" "unprognostic (1.23e-1)" "unprognostic (5.87e-2)" "unprognostic (6.88e-2)" "unprognostic (3.72e-3)" "unprognostic (3.31e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (6.41e-2)" "unprognostic (4.19e-1)" "unprognostic (1.89e-3)" "unprognostic (8.24e-2)" "unprognostic (1.86e-1)" "unprognostic (2.25e-2)" "unprognostic (2.55e-1)" 8.6 6.0 7.8 5.4 8.1 6.8 8.1 6.8 8.2 13.6 6.3 11.6 3.8 14.3 5.5 5.6 14.7 7.8 9.0 7.0 7.4 8.7 3.6 8.5 6.9 7.4 7.5 18.7 15.4 11.3 6.4 9.9 7.0 9.4 5.6 5.7 7.8 8.4 15.6 5.8 6.8 11.5 6.9 9.2 9.0 10.8 8.2 23.8 12.3 13.7 5.4 9.2 8.0 8.4 20.8 18.7 19.4 23.7 7.5 19.1 24.2 9.5 23.5 20.9 18.8 10.3 18.9 5.9 16.1 15.6 7.8 17.4 20.1 18.3 20.8 16.0 4.8 19.2 13.1 11.8 20.3 23.5 9.5 20.4 19.0 16.2 38.9 23.2 25.1 27.3 34.6 14.5 13.1 13.3 23.4 16.2 39.0 9.2 27.5 22.0 21.2 8.1 12.8 24.8 16.5 36.4 12.7 14.3 19.0 17.6 14.9 28.7 17.4 15.1 21.4 6.9 30.2 16.1 13.8 16.8 6.3 1.6 16.8 0.0 0.4 0.1 0.8 0.3 1.2 0.3 0.3 0.9 1.1 0.4 0.7 2.1 0.1 1.1 0.4 0.7 0.1 0.8 7.8 8.1 6.8 8.2 7.0 7.4 7.4 7.5 7.0 6.9 8.2 8.4 9.2 0.0 3.2 16.3 3.3 3.7 4.4 5.0 8.0 7.4 7.0 7.5 8.3 5.7 4.7 1.8 2.1 4.8 2.4 1.2 1.9 4.4 11.2 4.9 7.5 7.5 4.9 3.0 13.0 6.0 5.8 6.8 7.1 6.5 3.8 13.7 7.1 2.3 6.0 3.3 16.9 2.5 2.0 5.1 3.6 40.0 5.6 4.0 3.6 9.4 3.4 1.7 5.2 18.6 10.8 4.9 2.6 7.2 7.5 7.5 0.8 3.0 3.9 7.3 6.6 9.7 6.2 15.9 10.8 2.4 3.4 4.2 4.7 7.5 4.3 4.3 ZNF526 "KIAA1951, MGC4267" ENSG00000167625 "Zinc finger protein 526" Q8TF50 19 42220312-42228201 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 33.3;granulocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023070, HPA056609" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA023070: AB_2671057, HPA056609: AB_2683189" "unprognostic (2.04e-1)" "unprognostic (3.15e-1)" "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.46e-1)" "unprognostic (5.86e-2)" "unprognostic (9.09e-3)" "unprognostic (1.79e-1)" "unprognostic (8.84e-2)" "unprognostic (8.62e-3)" "unprognostic (1.28e-2)" "unprognostic (2.14e-1)" "unprognostic (1.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (2.81e-1)" "unprognostic (2.30e-1)" 3.4 2.5 2.1 2.8 2.3 3.8 3.1 4.3 2.6 3.9 2.0 3.3 3.3 3.6 2.3 3.1 3.5 1.9 2.8 2.0 2.1 2.3 2.8 2.6 4.0 2.4 2.2 4.5 3.5 3.9 3.0 3.0 2.3 3.3 2.1 2.0 4.6 3.3 5.1 5.2 3.1 2.4 1.6 3.6 3.1 3.5 2.4 4.2 2.8 4.0 3.6 3.5 3.4 3.4 7.8 24.8 7.1 6.4 8.0 7.7 6.2 8.9 8.2 9.2 10.1 13.0 5.5 12.6 6.3 9.5 4.2 5.7 7.7 9.7 5.7 7.5 9.2 12.6 12.0 12.5 7.5 8.1 7.8 7.6 7.7 9.2 9.6 5.7 5.8 6.7 12.3 7.8 5.9 10.8 8.2 5.2 4.7 6.8 8.7 9.4 8.7 5.7 4.2 14.0 7.3 6.4 10.2 10.1 7.2 5.4 4.1 14.4 7.8 11.3 7.7 4.8 11.2 9.3 5.9 8.5 7.5 7.8 9.5 1.8 3.6 1.4 4.5 3.6 6.9 4.7 3.5 4.1 2.8 4.4 4.2 5.3 0.7 3.4 5.3 4.2 3.9 3.3 2.1 2.3 4.3 2.6 2.0 2.1 2.4 2.2 2.3 1.6 2.4 3.4 3.0 22.4 33.3 2.0 6.9 5.5 4.4 2.8 4.0 7.4 3.1 2.4 3.2 0.0 17.1 3.7 14.6 8.0 3.2 5.7 3.9 4.1 5.8 1.7 4.0 7.1 13.8 9.5 1.4 3.0 8.3 7.4 4.6 2.3 25.2 4.9 3.6 2.6 4.6 6.7 1.5 4.2 2.0 6.8 1.8 6.3 7.2 7.0 0.0 1.9 5.8 4.1 11.3 1.0 1.4 2.9 2.8 3.0 6.1 4.6 7.8 2.8 9.2 9.6 0.0 5.7 3.6 9.9 10.1 1.9 5.1 10.3 6.7 3.7 5.7 2.6 ZNF543 DKFZp434H055 ENSG00000178229 "Zinc finger protein 543" Q08ER8 19 57320472-57330770 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 12.5;Late spermatids: 15.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046330 Approved Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA046330: " "unprognostic (9.20e-2)" "unprognostic (8.89e-2)" "unprognostic (2.60e-2)" "unprognostic (1.51e-1)" "unprognostic (1.45e-1)" "unprognostic (4.71e-1)" "unprognostic (2.45e-2)" "unprognostic (9.86e-2)" "unprognostic (1.01e-1)" "unprognostic (6.55e-2)" "unprognostic (2.44e-2)" "unprognostic (7.47e-2)" "prognostic favorable (2.03e-5)" "unprognostic (1.94e-1)" "unprognostic (1.10e-1)" "unprognostic (2.05e-1)" "unprognostic (2.84e-2)" 1.6 1.5 1.9 1.4 1.7 1.8 2.6 4.9 2.0 1.7 0.2 1.4 0.7 1.9 1.6 2.0 2.2 1.5 1.4 1.4 2.2 1.6 1.1 1.7 2.4 1.2 1.6 4.8 1.9 3.1 1.8 2.8 1.4 2.0 1.0 2.7 1.7 2.2 1.8 2.4 1.1 1.9 0.8 2.5 1.6 3.2 1.7 3.2 2.6 1.9 2.4 1.5 1.3 2.0 2.3 3.0 2.8 4.4 2.4 2.1 3.3 1.3 2.4 2.5 4.4 0.9 1.3 3.6 1.8 1.9 1.6 1.3 2.4 2.5 3.3 1.6 6.5 3.5 3.4 2.8 2.6 3.5 2.3 2.3 2.6 1.9 4.1 2.1 1.9 4.2 1.9 0.7 1.8 0.3 4.0 1.1 2.5 0.2 2.3 3.8 4.1 3.9 1.6 5.6 5.1 3.6 3.9 1.5 2.6 2.4 1.8 3.2 1.8 3.6 2.5 0.7 2.5 5.3 3.8 4.1 1.8 1.5 1.9 0.9 1.4 3.1 1.5 1.4 1.8 2.3 1.6 2.2 1.5 2.3 1.9 1.9 1.5 2.1 1.5 1.0 0.9 1.5 1.9 1.7 4.9 2.0 1.4 2.2 1.2 1.6 1.4 0.8 1.7 2.0 4.1 3.2 0.5 0.7 4.2 2.7 1.3 1.9 3.4 4.5 2.3 1.3 1.9 5.7 2.4 0.0 6.2 3.1 4.8 0.5 5.9 1.6 12.5 3.5 2.4 3.8 0.0 1.3 4.4 0.4 1.5 1.7 0.5 4.4 2.5 4.9 2.9 0.8 1.7 6.7 5.3 1.3 8.2 1.6 1.2 15.2 1.5 1.3 1.8 5.6 0.2 3.8 0.0 4.0 2.5 0.2 0.3 2.2 3.2 1.9 0.6 0.9 0.5 6.3 6.6 2.4 2.9 3.3 2.4 4.4 2.6 2.2 2.6 3.3 1.3 1.5 ZNF57 ZNF424 ENSG00000171970 "Zinc finger protein 57" Q68EA5 19 2900898-2918473 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.7;Early spermatids: 95.2;Late spermatids: 64.7;Squamous epithelial cells: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061915 Approved Nucleoli NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoli "HPA061915: AB_2684635" "unprognostic (3.59e-2)" "unprognostic (1.53e-3)" "unprognostic (1.91e-2)" "unprognostic (8.86e-3)" "unprognostic (3.32e-2)" "unprognostic (3.07e-2)" "unprognostic (7.66e-2)" "prognostic favorable (6.26e-4)" "unprognostic (1.35e-1)" "unprognostic (4.04e-2)" "prognostic favorable (7.72e-4)" "unprognostic (2.34e-3)" "prognostic favorable (4.11e-9)" "unprognostic (6.26e-3)" "unprognostic (2.82e-2)" "unprognostic (7.35e-2)" "unprognostic (6.49e-3)" 2.8 2.5 1.8 2.0 1.9 4.0 6.4 8.0 3.2 5.5 1.3 8.2 7.2 2.6 3.6 9.1 4.2 1.9 3.0 2.1 1.8 4.6 3.4 3.3 2.8 2.0 1.9 3.7 4.0 4.0 2.9 4.8 2.2 3.9 9.2 4.2 4.4 3.5 1.7 18.3 6.2 1.8 1.5 2.4 11.7 25.9 2.1 3.8 4.6 2.4 3.3 3.3 7.9 2.1 7.4 3.4 4.7 6.8 4.4 3.8 7.8 3.1 2.5 4.9 5.1 7.1 2.9 6.3 3.8 2.5 7.1 8.5 7.5 10.7 6.0 0.0 3.9 3.7 3.8 9.6 3.3 0.0 6.5 3.0 11.8 4.3 9.3 4.0 3.7 14.8 6.6 0.1 3.8 7.5 9.7 4.1 3.0 8.7 5.9 8.9 14.1 1.4 6.7 12.0 2.3 3.5 4.6 8.4 3.1 6.6 5.2 6.1 2.9 3.3 3.2 7.7 4.4 1.3 7.4 3.0 2.7 1.0 2.7 0.0 2.4 1.1 4.4 4.2 3.6 3.2 4.8 4.5 2.6 3.6 5.4 4.8 0.9 5.1 2.3 2.5 5.5 3.0 1.8 1.9 8.0 3.2 2.1 1.8 2.0 1.9 2.2 1.5 2.1 2.1 2.2 0.0 5.3 1.6 0.8 21.4 20.3 8.1 30.7 2.2 3.4 3.8 4.1 1.5 7.8 0.0 6.2 4.4 1.9 13.5 3.9 3.1 95.2 7.4 3.4 2.1 0.0 0.4 2.6 2.3 3.7 2.8 7.7 12.3 0.0 2.3 1.4 1.9 2.3 1.7 2.7 7.4 8.2 1.0 2.7 64.7 2.5 1.3 5.4 0.0 1.7 1.9 0.0 1.0 1.5 1.5 9.5 3.0 0.2 5.4 19.8 3.4 4.2 2.8 0.0 0.8 2.5 5.7 9.7 36.6 28.7 6.6 1.7 3.1 8.1 9.7 ZNF574 FLJ22059 ENSG00000105732 "Zinc finger protein 574" Q6ZN55 19 42068477-42081552 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 40.9;Spermatocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023196, HPA057274" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "HPA023196: AB_2671105, HPA057274: AB_2683392" "unprognostic (3.90e-1)" "unprognostic (3.68e-2)" "unprognostic (3.39e-2)" "unprognostic (7.84e-2)" "unprognostic (1.66e-1)" "unprognostic (2.11e-2)" "unprognostic (9.49e-2)" "unprognostic (2.84e-2)" "unprognostic (5.24e-2)" "unprognostic (1.55e-3)" "unprognostic (6.36e-3)" "unprognostic (2.11e-1)" "unprognostic (2.10e-2)" "unprognostic (6.48e-2)" "unprognostic (3.51e-2)" "unprognostic (2.97e-1)" "unprognostic (1.09e-3)" 8.1 5.4 6.8 4.6 6.1 11.1 7.9 9.5 7.7 8.4 4.3 9.5 6.7 10.3 2.7 9.6 8.8 5.1 6.8 6.2 6.2 5.5 5.4 5.6 6.5 6.9 5.8 9.6 7.9 6.1 6.5 5.0 5.8 7.5 2.8 4.1 8.1 6.7 9.3 12.8 7.5 3.7 5.6 8.4 7.2 27.1 6.3 6.3 6.0 6.4 4.2 8.2 7.5 6.3 15.0 41.1 9.0 11.4 8.1 8.0 9.7 11.0 9.6 14.2 13.6 16.2 10.1 21.4 9.7 9.1 7.5 8.9 10.4 14.1 5.6 11.4 17.6 20.5 10.1 14.0 8.6 12.6 13.5 9.5 13.9 13.2 11.1 8.7 7.9 11.8 17.1 13.3 10.1 31.2 15.2 10.9 16.1 13.5 16.2 20.7 8.6 9.3 7.4 19.7 14.9 12.8 11.3 24.0 7.3 6.2 11.0 20.5 9.5 19.2 14.9 5.8 16.4 14.3 9.3 15.7 10.6 11.9 11.0 12.3 10.5 16.7 16.2 7.8 17.6 17.3 12.1 17.8 12.5 12.8 12.6 11.9 13.3 10.9 11.2 11.1 10.3 12.9 6.8 6.1 9.5 7.7 6.2 6.2 6.9 5.8 5.8 5.6 6.3 6.3 6.0 0.0 3.3 1.3 11.3 29.3 15.1 6.1 40.9 7.5 11.0 7.6 4.3 4.3 6.0 1.8 2.1 7.9 6.3 5.8 1.9 6.9 25.3 6.1 5.7 7.6 3.5 8.6 1.4 5.1 6.7 6.6 7.7 5.7 12.7 5.4 6.8 3.1 5.1 3.3 1.7 7.6 6.1 2.5 11.0 15.7 5.6 3.0 8.8 1.0 7.5 3.9 4.1 1.5 0.9 4.3 8.5 8.6 8.1 10.6 6.4 4.3 5.2 9.8 6.6 8.8 8.0 35.5 20.5 22.1 22.7 4.8 10.6 3.8 7.9 9.6 ZNF584 FLJ39899 ENSG00000171574 "Zinc finger protein 584" Q8IVC4 19 58401504-58418327 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 49.8" "Low region specificity" "Detected in all" "HPA043408, HPA048075" Uncertain Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "HPA043408: AB_2678466, HPA048075: AB_2680251" "unprognostic (6.06e-2)" "unprognostic (3.27e-3)" "unprognostic (3.76e-3)" "unprognostic (8.15e-3)" "unprognostic (5.50e-2)" "unprognostic (1.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.04e-2)" "unprognostic (6.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-3)" "unprognostic (1.90e-3)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (1.80e-1)" "unprognostic (3.27e-1)" "unprognostic (1.36e-2)" 5.7 6.7 4.6 2.9 4.5 1.8 5.0 5.4 5.5 5.6 6.0 6.6 3.5 6.9 3.8 5.8 6.8 2.3 8.9 5.1 4.3 5.3 6.6 4.3 2.5 5.3 4.6 6.1 4.9 8.4 6.7 2.7 4.6 5.0 2.6 5.1 4.7 5.7 9.8 9.0 3.5 5.1 4.0 3.3 5.6 4.7 4.5 3.2 4.7 10.9 3.4 6.1 5.0 4.1 11.7 16.7 11.2 14.7 10.8 10.7 4.5 8.9 15.8 5.4 6.7 2.7 3.5 5.8 7.0 14.7 14.2 6.5 12.1 14.6 6.1 7.5 49.8 15.7 9.6 3.5 18.3 17.3 4.3 11.1 10.4 16.5 22.8 11.9 10.9 9.5 15.8 5.4 8.9 8.3 14.4 5.4 2.8 7.6 23.2 10.4 8.4 9.0 7.6 13.7 9.0 9.5 19.5 5.6 7.4 2.9 3.7 8.6 7.0 21.2 6.5 8.9 14.3 5.0 9.5 1.3 15.2 6.0 7.1 0.0 2.2 0.8 3.2 2.1 5.2 2.1 4.3 4.5 3.4 3.3 2.3 3.6 0.7 3.2 3.5 2.9 5.1 2.7 4.6 4.5 5.4 5.5 5.1 4.3 5.3 4.6 4.6 4.0 4.5 4.1 4.2 3.2 3.9 1.0 2.3 11.2 3.2 5.6 6.2 4.1 4.8 4.3 12.8 5.7 2.1 9.2 4.2 1.0 5.9 1.6 13.7 5.6 9.6 8.1 6.1 4.6 6.7 9.5 2.0 5.1 1.5 5.6 3.6 1.8 2.5 5.5 6.8 4.7 2.6 3.3 2.2 2.3 4.1 2.4 3.3 7.8 5.3 2.1 1.8 0.0 1.3 6.1 2.1 0.5 1.6 4.9 2.8 6.4 2.6 4.2 2.1 5.5 10.2 9.2 6.6 4.4 6.3 8.1 3.7 4.3 15.9 0.4 4.0 12.3 3.2 2.0 ZNF703 "FLJ14299, NLZ1, ZEPPO1, ZNF503L, Zpo1" ENSG00000183779 "Zinc finger protein 703" Q9H7S9 8 37695782-37700019 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 108.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 434.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "intermediate monocyte: 3.3;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 12 "monocytes: 4.3" "Cell line enhanced" "Detected in many" "HEK 293: 156.8;OE19: 61.2;SK-MEL-30: 60.0;T-47d: 52.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023930, CAB068249" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB068249: AB_2665667, HPA023930: AB_1859425" "unprognostic (4.64e-2)" "unprognostic (3.15e-2)" "unprognostic (7.01e-3)" "unprognostic (1.71e-3)" "unprognostic (2.54e-1)" "unprognostic (1.42e-1)" "unprognostic (6.93e-2)" "unprognostic (4.23e-2)" "unprognostic (1.35e-1)" "unprognostic (1.84e-1)" "unprognostic (4.09e-1)" "unprognostic (9.63e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (5.63e-2)" "unprognostic (1.52e-1)" "unprognostic (1.01e-1)" "unprognostic (2.23e-1)" 24.6 14.4 16.6 7.6 15.0 1.9 27.4 10.7 16.9 39.9 9.8 46.9 15.1 27.8 12.7 18.2 33.2 6.2 18.8 14.2 10.3 8.1 4.2 10.7 4.1 21.8 17.9 19.6 8.7 1.9 5.9 12.1 16.4 21.7 12.6 0.4 18.3 8.7 108.4 57.4 25.9 11.6 15.0 18.9 22.8 2.9 14.7 2.8 10.6 33.3 2.9 36.8 28.7 10.7 3.2 6.6 0.8 5.2 15.1 7.9 5.2 29.1 13.6 8.8 7.4 27.2 36.0 0.0 7.2 18.4 4.0 17.2 3.0 4.4 6.8 0.8 156.8 0.0 9.5 17.5 14.9 0.0 3.0 26.6 8.2 9.1 3.7 19.0 7.8 0.3 0.4 0.0 14.1 27.4 0.1 0.8 2.6 61.2 11.6 2.7 4.7 3.7 2.7 14.2 2.9 0.2 5.4 4.6 60.0 6.2 52.6 3.1 23.1 10.3 23.7 16.1 12.3 1.9 0.1 0.2 9.1 3.2 6.7 0.0 0.4 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.1 16.6 15.0 10.7 16.9 14.2 10.3 21.8 17.9 16.4 15.0 14.7 10.7 11.9 6.4 0.0 14.7 15.3 48.2 13.2 28.9 103.0 3.7 39.3 27.8 9.1 2.8 14.5 5.5 0.0 41.4 7.7 52.0 3.9 7.1 0.4 30.8 37.0 9.5 79.6 0.0 1.5 2.5 37.2 36.0 14.8 20.3 0.0 5.8 2.5 2.2 36.2 0.0 2.8 95.4 10.2 23.6 31.9 0.7 31.4 31.2 33.8 11.2 7.9 9.3 0.0 0.0 0.6 3.7 56.9 15.8 1.9 9.7 35.4 2.8 7.7 0.9 52.6 54.9 66.4 0.0 0.6 99.7 74.6 434.1 6.0 6.1 92.6 10.7 ZNF706 HSPC038 ENSG00000120963 "Zinc finger protein 706" Q9Y5V0 8 101177878-101206193 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1090.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042793 Approved "Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA042793: AB_10795710" "unprognostic (2.05e-2)" "unprognostic (3.29e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (3.12e-5)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "unprognostic (2.48e-3)" "unprognostic (5.22e-2)" "unprognostic (3.19e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.90e-11)" "unprognostic (9.65e-2)" "unprognostic (1.59e-1)" "unprognostic (3.57e-1)" "unprognostic (2.17e-2)" 99.5 83.4 85.6 57.3 85.3 76.9 92.6 89.1 114.7 86.7 54.6 93.3 93.3 71.5 90.4 147.2 69.0 69.2 86.0 87.2 72.9 95.9 96.0 81.9 95.5 69.0 72.8 70.2 269.9 69.8 93.9 55.3 69.6 70.9 87.2 46.9 99.1 49.1 110.7 180.0 100.0 50.7 69.7 100.5 92.7 118.1 70.0 67.2 82.3 86.1 102.5 75.1 101.1 83.1 203.0 113.9 196.0 62.7 69.0 78.0 124.8 82.4 105.5 83.5 89.0 81.8 121.5 121.9 139.4 99.1 170.4 108.4 113.3 111.0 95.8 90.5 98.0 122.1 69.5 159.2 90.7 92.2 114.1 69.1 170.9 78.9 170.7 115.1 144.0 121.4 134.8 230.6 75.0 142.6 194.5 252.2 59.7 408.6 278.8 80.8 65.3 251.1 112.7 103.2 129.4 57.6 57.6 95.0 375.9 166.3 99.3 96.5 96.3 45.6 93.9 121.9 87.0 194.1 202.6 197.0 123.5 199.2 215.8 255.1 280.0 162.6 138.0 463.2 143.4 400.0 191.5 178.0 264.1 344.1 214.7 206.3 38.7 130.9 492.1 532.8 302.8 268.7 85.6 85.3 89.1 114.7 87.2 72.9 69.0 72.8 69.6 69.7 70.0 83.1 131.4 60.9 41.0 29.0 188.6 459.7 242.3 252.7 149.7 59.3 159.3 182.6 79.8 137.2 138.1 79.1 18.8 190.6 175.0 288.4 180.0 264.5 439.7 125.5 70.1 137.7 265.1 107.1 31.5 259.8 339.0 131.4 106.5 114.9 122.2 85.1 99.2 123.4 265.3 85.8 21.1 275.3 231.9 162.3 186.4 1090.7 86.9 214.8 206.3 16.9 298.4 131.3 114.4 14.6 57.6 401.5 265.4 86.9 329.4 326.5 339.2 195.1 110.8 55.9 105.2 111.6 169.8 84.3 82.7 224.8 518.0 193.3 112.7 72.7 153.5 311.7 ZNF726 ZNF92P3 ENSG00000213967 "Zinc finger protein 726" A6NNF4 19 23914876-23945159 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 8.2;NK-cell: 3.1" "Group enriched" "Detected in many" 4 "granulocytes: 8.2;NK-cells: 3.1" "Cell line enhanced" "Detected in many" "MOLT-4: 29.6" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (5.40e-2)" "unprognostic (2.27e-1)" "unprognostic (4.41e-3)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "unprognostic (4.97e-2)" "unprognostic (1.80e-1)" "unprognostic (2.91e-2)" "unprognostic (8.26e-4)" "unprognostic (5.65e-4)" "unprognostic (2.14e-2)" "unprognostic (9.87e-3)" "unprognostic (2.90e-2)" "unprognostic (4.25e-2)" "unprognostic (1.64e-1)" "unprognostic (4.97e-2)" "unprognostic (3.20e-3)" 1.2 1.3 2.5 1.8 1.8 5.8 4.2 3.8 2.3 2.9 0.9 1.9 1.2 2.2 5.1 2.4 1.7 2.1 0.7 2.0 2.6 2.8 2.2 1.6 4.2 1.9 2.2 1.4 0.7 2.1 0.6 3.4 2.2 2.5 3.9 3.2 1.3 2.0 1.6 4.8 1.3 1.0 1.6 2.5 3.0 2.9 3.4 6.1 2.2 1.0 3.4 1.7 2.8 2.5 1.1 1.9 16.3 9.0 1.1 1.1 0.8 4.0 1.4 8.7 8.3 1.4 5.3 0.1 7.5 1.7 6.3 1.2 15.2 0.2 11.8 11.3 8.0 6.6 1.5 0.4 0.6 0.1 3.8 1.2 0.9 5.2 0.3 1.0 0.0 9.5 5.2 0.1 3.3 5.6 29.6 19.8 9.8 0.1 8.4 21.6 12.1 4.8 3.0 6.6 5.4 9.1 0.0 0.1 4.1 7.9 10.5 1.3 1.1 3.1 2.3 13.5 8.5 0.1 9.2 13.1 0.1 2.4 4.5 8.2 0.4 0.2 0.4 0.5 0.2 0.7 1.0 1.0 0.4 1.0 1.0 1.2 0.8 3.1 0.3 1.1 1.2 0.6 2.5 1.8 3.8 2.3 2.0 2.6 1.9 2.2 2.2 1.6 3.4 2.5 0.6 3.2 0.0 2.9 2.4 0.9 1.6 0.2 0.6 3.8 2.4 1.3 4.5 1.5 1.1 3.7 0.0 7.2 2.9 1.5 1.9 1.4 0.1 1.8 2.4 2.2 0.0 9.0 1.0 0.2 6.7 1.8 0.0 2.6 3.8 5.3 1.4 2.0 2.2 5.0 2.4 0.7 2.0 1.9 2.0 0.3 0.3 1.2 0.0 0.0 0.8 0.6 3.1 5.0 2.9 0.6 0.3 1.9 1.4 0.9 0.1 0.5 2.5 1.2 0.0 1.7 1.7 2.3 6.0 2.0 1.7 4.1 2.4 1.8 0.5 1.5 ZNF750 "FLJ13841, Zfp750" ENSG00000141579 "Zinc finger protein 750" Q32MQ0 17 82829434-82840022 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 96.1;skin 1: 139.0;vagina: 51.7" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 33.3;Squamous epithelial cells: 156.8;Suprabasal keratinocytes: 41.1;Syncytiotrophoblasts: 68.1;Urothelial cells: 51.3" "Cancer enhanced" "Detected in many" "cervical cancer: 20.5;head and neck cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.3;hTCEpi: 7.2;MCF7: 5.4;SK-BR-3: 14.0" "Not detected" "Not detected" "HPA021573, HPA023012" Enhanced NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA021573: AB_1859438, HPA023012: AB_1859439" "unprognostic (3.46e-3)" "unprognostic (1.94e-2)" "unprognostic (7.51e-2)" "unprognostic (2.63e-1)" "unprognostic (1.45e-1)" "unprognostic (9.73e-2)" "unprognostic (4.48e-2)" "unprognostic (6.55e-3)" "unprognostic (1.34e-1)" "unprognostic (4.33e-2)" "unprognostic (6.30e-3)" "unprognostic (1.23e-2)" "unprognostic (5.30e-3)" "unprognostic (3.04e-2)" "unprognostic (5.94e-2)" "unprognostic (2.04e-1)" "unprognostic (4.25e-2)" 0.5 0.1 0.8 0.0 1.2 0.1 5.1 0.5 0.9 25.0 0.0 0.1 0.1 0.2 4.1 96.1 0.6 0.2 0.6 0.6 0.2 0.4 0.1 2.0 0.0 1.0 0.3 0.1 0.2 2.2 2.9 3.9 1.0 3.3 0.0 0.0 33.6 2.7 12.0 139.0 0.1 0.0 0.2 0.1 0.2 0.4 0.6 5.1 3.5 0.0 14.7 4.9 51.7 2.3 0.1 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.3 1.2 1.0 0.0 14.0 0.0 1.7 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.5 0.9 0.6 0.2 1.0 0.3 1.0 0.2 0.6 2.3 0.6 0.0 8.2 0.0 0.0 5.2 14.3 19.6 9.1 0.0 7.4 5.0 0.4 0.0 21.2 0.0 0.0 23.1 0.0 0.0 0.0 0.0 2.4 27.1 3.3 0.9 0.0 0.0 0.4 0.0 1.9 0.3 0.0 33.3 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.0 10.2 0.0 0.3 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 7.6 0.0 0.1 14.2 0.0 0.0 0.1 1.5 0.0 0.2 156.8 41.1 68.1 0.2 0.0 0.0 51.3 ZNF777 KIAA1285 ENSG00000196453 "Zinc finger protein 777" Q9ULD5 7 149431363-149461062 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003252 Approved Approved Nucleoplasm NA NA "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA003252: AB_1080755" "unprognostic (7.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.17e-2)" "unprognostic (3.37e-2)" "unprognostic (4.78e-2)" "unprognostic (6.64e-2)" "unprognostic (5.87e-3)" "unprognostic (4.52e-2)" "unprognostic (1.10e-1)" "unprognostic (6.15e-2)" "unprognostic (5.17e-3)" "unprognostic (2.64e-1)" "unprognostic (4.00e-2)" "unprognostic (6.33e-2)" "unprognostic (1.68e-1)" "unprognostic (8.23e-2)" "unprognostic (5.72e-2)" 7.5 6.6 5.9 4.4 5.4 7.9 7.7 5.8 7.0 8.7 2.3 9.0 4.5 10.4 3.3 6.2 8.4 3.6 7.1 6.0 6.3 6.2 7.3 5.3 5.1 5.9 5.3 10.0 7.5 6.4 8.5 4.9 5.1 8.9 3.3 3.4 7.5 5.2 13.9 11.7 6.3 5.2 4.7 6.7 7.3 6.7 5.9 5.7 7.3 7.0 3.9 9.0 7.9 5.5 14.9 18.0 11.9 17.3 8.7 7.0 15.3 9.4 9.9 12.5 10.8 11.3 9.3 9.4 18.5 10.7 7.7 9.7 11.7 14.3 6.8 15.3 17.8 9.2 5.0 11.4 14.7 13.2 12.9 8.3 16.1 10.1 14.6 6.6 6.8 12.4 30.2 0.0 7.2 19.2 27.9 18.0 14.5 6.6 10.5 22.7 6.1 19.8 7.7 11.4 12.9 18.1 16.2 16.5 15.7 4.3 7.8 21.7 10.7 10.4 4.1 20.8 15.5 8.6 8.2 4.4 7.8 9.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.9 5.4 5.8 7.0 6.0 6.3 5.9 5.3 5.1 4.7 5.9 5.5 4.0 0.0 1.7 5.9 3.8 1.1 1.4 0.3 2.8 6.5 3.9 5.5 2.9 2.8 0.1 1.8 6.2 2.0 4.2 3.1 0.0 1.2 2.6 2.9 4.8 2.9 1.8 6.6 6.9 1.0 3.8 2.8 2.0 4.5 0.0 8.2 2.9 5.7 1.6 1.7 6.7 3.1 0.0 2.2 1.3 3.8 2.8 2.0 0.0 4.7 0.2 5.5 2.1 3.0 3.5 1.1 3.1 3.4 1.6 2.4 1.4 1.6 0.8 5.5 0.0 5.2 3.7 1.5 4.6 2.5 1.8 3.8 3.5 6.6 2.8 1.0 ZNF831 "C20orf174, dJ492J12.1" ENSG00000124203 "Zinc finger protein 831" Q5JPB2 20 59123381-59259113 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;lymphoid tissue: 6.2" "Group enriched" "Detected in some" 4 "dendritic cells: 20.5;Excitatory neurons: 19.5;NK-cells: 17.5;Plasma cells: 9.5;T-cells: 31.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 1.2;T-cells: 2.1" "Group enriched" "Detected in some" 6 "Daudi: 4.0;HMC-1: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 25 "amygdala: 4.6;basal ganglia: 4.1;cerebral cortex: 3.4;hippocampal formation: 5.0;olfactory bulb: 5.4" HPA016839 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA016839: AB_1859466" "unprognostic (2.90e-3)" "unprognostic (7.70e-6)" "unprognostic (9.71e-4)" "unprognostic (1.31e-3)" "unprognostic (7.00e-2)" "unprognostic (3.00e-5)" "unprognostic (3.08e-3)" "unprognostic (2.23e-2)" "unprognostic (2.89e-3)" "unprognostic (2.21e-3)" "unprognostic (2.80e-3)" "unprognostic (4.31e-1)" "unprognostic (3.40e-3)" "unprognostic (2.39e-1)" "unprognostic (3.42e-2)" "unprognostic (2.21e-1)" "unprognostic (1.93e-2)" 0.3 0.1 2.2 2.3 1.6 0.9 0.3 0.0 2.7 0.1 0.0 0.3 0.2 0.1 0.2 0.2 0.2 0.5 0.0 3.4 0.3 0.1 0.2 0.6 6.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.1 1.9 0.0 0.0 2.6 0.6 0.2 0.9 1.5 0.3 0.0 3.8 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.8 0.0 1.4 0.2 1.0 1.5 0.0 0.1 0.8 1.0 0.1 1.2 0.0 0.0 2.1 0.4 2.2 1.6 0.0 2.7 3.4 0.3 0.0 0.0 0.0 0.0 0.9 0.2 0.3 0.0 0.6 0.7 4.8 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.7 0.0 0.0 1.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 19.5 0.0 0.0 0.1 0.5 0.1 2.5 0.0 0.7 0.0 0.0 0.0 2.0 0.0 0.0 0.6 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 17.5 0.5 0.9 0.0 0.0 0.0 9.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.5 0.5 0.0 0.0 0.0 31.2 0.0 0.0 0.0 ZNF843 MGC46336 ENSG00000176723 "Zinc finger protein 843" Q8N446 16 31432593-31443160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 4.6;Cardiomyocytes: 5.3;Prostatic glandular cells: 3.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 2.3;EFO-21: 1.8;HMC-1: 1.6" "HPA030911, HPA030912, HPA077945" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nuclear speckles" "HPA030911: AB_2673656, HPA030912: AB_10670434, HPA077945: " "unprognostic (9.27e-2)" "unprognostic (1.32e-1)" "unprognostic (3.43e-3)" "unprognostic (9.24e-2)" "unprognostic (1.33e-1)" "unprognostic (6.25e-3)" "unprognostic (2.86e-1)" "unprognostic (8.30e-3)" "unprognostic (3.55e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-3)" "unprognostic (2.93e-3)" "unprognostic (5.96e-3)" "unprognostic (1.23e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-5)" "unprognostic (1.17e-1)" 0.6 0.5 1.5 0.3 1.2 0.3 0.6 2.5 1.3 1.0 0.0 0.4 0.2 1.0 0.7 0.4 1.1 0.7 1.7 1.6 1.9 0.6 0.4 0.3 0.3 1.1 1.4 3.0 2.1 0.9 1.5 0.4 0.9 0.6 0.1 1.1 1.5 0.8 2.2 0.9 0.3 0.5 1.1 0.4 0.4 0.5 1.8 0.2 1.0 0.8 0.2 0.5 0.6 0.9 0.1 0.3 0.2 1.2 2.3 0.6 0.0 0.2 0.2 0.0 0.1 0.1 0.3 0.0 1.8 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.6 0.2 1.6 1.2 0.3 0.0 0.1 0.8 0.0 0.2 0.2 0.2 0.6 0.8 0.1 0.4 0.7 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.7 0.1 0.3 0.2 0.1 0.2 0.0 0.2 0.2 0.8 0.0 0.2 0.1 0.1 0.0 0.1 0.4 1.0 0.2 0.2 0.7 0.1 0.4 0.2 0.2 0.7 0.1 0.2 0.1 0.4 0.7 1.7 0.1 0.2 0.1 1.0 1.5 1.2 2.5 1.3 1.6 1.9 1.1 1.4 0.9 1.1 1.8 0.9 0.5 0.0 0.5 2.9 0.3 0.8 4.6 0.1 0.0 2.2 0.9 1.3 5.3 0.0 0.7 0.0 2.1 0.3 0.1 0.3 0.0 0.3 0.2 0.4 2.0 1.0 1.2 0.0 1.4 0.2 0.1 1.4 0.0 0.4 1.3 1.4 1.8 0.3 0.6 0.0 1.7 0.0 0.0 0.3 2.1 0.0 1.5 0.9 0.0 0.0 0.1 1.4 2.1 1.0 1.3 0.1 0.1 1.5 0.1 3.6 0.0 0.4 0.0 1.9 0.0 2.8 1.3 0.4 0.7 0.1 1.4 0.3 1.2 0.8 0.1 1.9 ZNF853 DKFZp434J1015 ENSG00000236609 "Zinc finger protein 853" P0CG23 7 6615610-6624290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.2;Granulosa cells: 15.1;Muller glia cells: 13.2;Sertoli cells: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 20.1;SH-SY5Y: 29.5;U-2 OS: 19.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA067690 Approved Approved Nucleoli NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoli "HPA067690: AB_2685888" "unprognostic (1.35e-3)" "unprognostic (2.63e-1)" "unprognostic (7.17e-2)" "unprognostic (8.77e-2)" "unprognostic (2.76e-1)" "unprognostic (1.96e-1)" "unprognostic (1.17e-1)" "unprognostic (3.54e-1)" "unprognostic (2.26e-2)" "unprognostic (5.06e-2)" "unprognostic (1.87e-3)" "unprognostic (9.28e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.41e-3)" "unprognostic (4.95e-2)" "unprognostic (2.30e-3)" "unprognostic (4.01e-2)" 4.1 2.8 24.8 2.3 24.7 0.6 4.5 20.4 24.0 9.6 11.8 12.9 1.1 11.3 4.4 4.3 9.2 4.5 10.5 23.7 23.7 4.9 0.5 3.7 2.9 27.8 27.9 12.0 7.0 5.5 6.6 2.8 25.1 7.8 1.7 5.1 5.4 8.6 27.1 3.1 4.4 6.6 25.6 3.5 4.9 2.6 24.8 3.3 7.9 20.2 2.0 10.1 4.9 21.0 0.0 1.6 4.7 20.1 0.2 0.0 0.2 0.4 0.0 2.1 0.4 3.6 0.8 0.0 7.8 0.0 0.7 0.0 7.2 0.2 2.0 0.0 2.6 0.6 0.0 3.8 2.8 0.0 0.1 0.7 0.6 0.2 0.1 2.0 0.0 1.6 3.2 0.1 1.3 0.1 0.5 2.7 7.5 0.0 0.0 2.3 7.8 0.1 1.5 7.6 6.3 29.5 0.0 0.3 1.2 3.9 1.1 4.3 0.0 1.5 19.5 0.0 1.9 0.4 0.1 0.1 0.0 0.0 7.8 0.0 0.0 0.8 0.2 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 24.8 24.7 20.4 24.0 23.7 23.7 27.8 27.9 25.1 25.6 24.8 21.0 4.3 0.0 0.0 2.0 1.0 0.5 1.5 0.2 1.2 13.2 3.2 4.4 10.4 0.0 0.6 7.3 6.2 0.0 2.0 0.1 0.0 0.6 1.6 7.5 4.3 3.2 1.8 0.4 1.5 0.7 0.0 4.4 0.5 2.3 0.0 15.1 2.5 0.0 0.1 5.0 2.7 0.0 0.0 0.0 0.9 2.4 5.3 0.2 3.6 1.9 0.1 13.2 1.0 2.0 2.8 0.4 0.1 8.6 1.3 3.3 0.0 0.2 2.3 10.4 13.1 6.4 5.4 0.5 0.5 0.4 0.3 0.3 1.8 6.9 0.1 0.7 ZNRF1 "DKFZp434E229, FLJ14846, nin283" ENSG00000186187 "Zinc and ring finger 1" Q8ND25 16 74999024-75110994 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.4;T-reg: 2.4" "Group enriched" "Detected in many" 4 "granulocytes: 2.4;T-cells: 2.4" "Cell line enhanced" "Detected in all" "HMC-1: 176.9;MOLT-4: 134.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027470 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA027470: AB_10603108" "unprognostic (2.78e-2)" "prognostic favorable (9.90e-4)" "unprognostic (4.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.34e-2)" "unprognostic (1.18e-2)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-2)" "unprognostic (5.38e-2)" "unprognostic (3.69e-1)" "unprognostic (2.28e-1)" "unprognostic (1.46e-1)" "unprognostic (4.89e-2)" "unprognostic (2.87e-1)" "unprognostic (2.10e-2)" "unprognostic (1.44e-2)" 18.7 16.5 21.1 9.6 22.3 6.7 17.8 9.1 22.8 25.3 19.0 30.6 9.6 22.5 9.5 65.9 18.0 7.5 21.0 23.4 24.5 14.7 17.6 24.1 7.7 19.6 22.5 17.4 11.5 11.8 13.4 11.2 18.6 13.7 12.1 7.4 16.9 7.0 81.2 25.0 15.3 11.4 13.4 4.5 21.0 37.4 30.7 53.2 29.3 30.6 13.3 22.5 26.4 17.5 10.9 15.7 26.7 27.5 27.7 21.4 91.2 13.0 18.3 17.5 17.1 25.4 33.2 2.9 9.9 28.3 16.8 25.5 13.0 17.8 13.9 26.7 7.5 56.7 4.8 47.0 22.0 27.5 176.9 19.5 14.7 18.4 14.9 30.8 29.0 68.3 27.8 8.8 13.7 104.5 134.6 100.6 37.1 31.4 16.7 59.0 10.0 17.4 25.1 30.5 35.4 37.7 20.7 27.0 8.3 21.7 71.6 25.8 19.9 12.0 21.0 21.5 7.9 50.5 55.1 31.6 15.8 30.2 12.6 2.4 0.5 0.4 0.0 0.5 0.5 0.0 0.6 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.5 0.0 2.4 0.1 21.1 22.3 9.1 22.8 23.4 24.5 19.6 22.5 18.6 13.4 30.7 17.5 34.8 9.6 14.4 16.6 1.8 15.9 16.0 11.2 4.6 12.6 24.3 22.4 16.4 18.6 14.0 3.7 52.1 6.4 2.3 25.5 0.0 8.9 25.9 30.7 15.1 30.2 19.8 30.5 45.2 12.7 10.1 15.1 18.3 28.0 36.8 23.7 12.8 14.4 10.4 3.3 42.4 14.0 14.2 7.3 10.9 16.3 6.8 7.3 14.2 33.7 7.6 15.0 0.0 33.7 29.5 20.0 12.1 4.1 1.8 17.2 9.6 6.2 15.1 6.5 0.0 12.4 14.7 13.6 18.7 21.0 19.6 4.5 13.3 16.7 12.7 29.6 ZP1 ENSG00000149506 "Zona pellucida glycoprotein 1" P60852 11 60867562-60875693 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Early spermatids: 32.3;Late spermatids: 87.6" "Cancer enhanced" "Detected in single" "prostate cancer: 0.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 32 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 32 "dendritic cells: 3.1" "Group enriched" "Detected in some" 40 "RPMI-8226: 12.4;SK-BR-3: 3.3" "Not detected" "Not detected" "Secreted in female reproductive system" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (6.40e-3)" "unprognostic (2.18e-4)" "unprognostic (1.63e-1)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (7.02e-2)" "unprognostic (8.27e-2)" "unprognostic (9.95e-2)" "unprognostic (1.94e-2)" "unprognostic (8.15e-3)" "unprognostic (2.52e-1)" "unprognostic (9.25e-4)" "unprognostic (5.31e-13)" "unprognostic (4.13e-2)" "unprognostic (2.38e-1)" "unprognostic (6.27e-2)" "unprognostic (5.61e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 1.3 0.3 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.1 0.7 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 32.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 87.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 6.6 0.1 5.0 1.9 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.1 ZSCAN22 "HKR2, ZNF50" ENSG00000182318 "Zinc finger and SCAN domain containing 22" P10073 19 58326994-58342332 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 14.7" "Low region specificity" "Detected in all" HPA006471 Uncertain Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "Actin filaments" "HPA006471: AB_2221026" "unprognostic (5.55e-3)" "unprognostic (2.24e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (3.82e-2)" "unprognostic (2.47e-3)" "unprognostic (1.52e-1)" "unprognostic (2.91e-1)" "unprognostic (1.15e-1)" "unprognostic (2.15e-3)" "unprognostic (5.00e-2)" "unprognostic (7.59e-2)" "unprognostic (2.59e-2)" "unprognostic (1.74e-1)" "unprognostic (5.22e-3)" "unprognostic (1.07e-1)" 1.2 1.5 1.4 1.3 1.7 0.7 1.1 2.9 1.6 1.7 1.0 1.5 1.2 1.5 0.8 1.8 1.3 0.7 1.2 1.3 1.4 1.3 2.4 1.1 1.2 1.4 1.2 1.5 1.4 1.6 2.6 1.2 1.4 1.4 0.9 0.8 1.2 1.0 1.1 2.3 1.3 1.2 0.8 1.4 1.4 1.2 1.2 1.1 1.3 1.0 1.4 1.5 1.5 2.8 2.4 4.2 2.3 3.5 2.6 1.6 2.4 2.0 1.0 1.2 1.1 2.3 1.7 1.9 1.3 1.6 1.5 1.8 3.3 2.2 1.3 3.0 14.7 4.1 4.2 2.1 2.1 3.3 4.2 1.8 2.2 2.6 2.7 2.2 1.8 1.9 4.1 3.6 2.1 1.9 1.6 1.5 2.0 3.0 4.8 2.2 3.6 3.3 1.2 3.1 3.6 2.6 3.0 4.0 2.0 1.8 1.9 2.3 1.8 6.5 1.9 1.6 3.5 3.6 5.3 1.4 2.6 2.2 2.3 0.0 0.8 1.0 2.0 0.7 1.3 0.8 1.1 1.6 1.1 1.0 0.9 1.0 0.2 1.2 0.9 0.5 0.9 1.0 1.4 1.7 2.9 1.6 1.3 1.4 1.4 1.2 1.4 0.8 1.2 2.8 1.1 0.0 4.1 1.6 1.5 1.8 0.6 1.0 0.0 0.7 1.3 0.9 0.6 1.5 1.6 1.8 0.0 0.9 0.8 0.4 1.9 0.9 0.3 1.1 1.2 0.9 0.0 1.7 2.1 0.6 0.9 1.1 1.1 1.6 0.0 1.1 0.0 1.3 0.5 1.7 2.1 0.5 0.0 0.8 0.8 0.0 2.1 2.3 1.8 0.0 1.3 0.5 0.0 1.0 2.2 1.1 1.6 0.4 1.1 0.9 0.8 0.6 1.1 0.7 0.0 1.7 0.8 4.3 1.9 1.1 3.7 0.7 1.2 0.9 1.0 0.4 ZW10 KNTC1AP ENSG00000086827 "Zw10 kinetochore protein" O43264 11 113733187-113773735 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, ER-Golgi transport, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 44.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011565, HPA051253, HPA055410" Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Endoplasmic reticulum, Cytosol" "CAB011565: AB_779030, HPA051253: AB_2681408, HPA055410: AB_2682809" "unprognostic (4.33e-3)" "unprognostic (6.65e-2)" "prognostic favorable (2.70e-4)" "unprognostic (3.12e-1)" "unprognostic (5.51e-2)" "unprognostic (6.52e-2)" "prognostic unfavorable (8.57e-4)" "unprognostic (7.44e-2)" "unprognostic (8.01e-3)" "unprognostic (5.91e-2)" "unprognostic (1.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.57e-3)" "unprognostic (6.00e-2)" "unprognostic (8.73e-2)" "unprognostic (2.95e-1)" "unprognostic (1.17e-3)" 6.9 6.0 3.5 8.1 4.1 9.2 10.9 5.0 4.8 8.1 3.7 8.3 7.2 7.6 7.3 9.6 6.1 5.9 5.6 3.8 3.8 8.8 13.0 6.4 9.4 4.2 4.7 6.9 9.1 7.2 5.1 7.7 4.6 7.9 10.0 6.8 8.3 7.3 13.4 13.7 7.1 8.7 3.8 7.0 7.3 13.5 4.2 12.1 6.7 12.0 12.0 8.5 7.5 5.7 25.0 14.4 30.2 22.1 18.4 20.0 17.4 26.1 21.4 32.2 32.5 38.1 46.1 29.0 34.5 25.8 28.1 34.2 36.7 31.6 46.0 19.1 15.1 30.9 12.0 23.5 20.6 31.7 18.8 16.5 20.8 34.1 27.4 14.2 33.5 31.7 36.3 11.8 33.8 12.2 29.3 20.9 21.7 29.8 29.0 27.0 34.4 32.7 21.2 22.2 13.3 15.7 29.1 24.2 11.8 24.2 44.9 17.4 21.1 28.8 44.2 14.4 28.8 6.1 10.6 30.6 9.9 38.1 33.0 8.5 7.4 7.4 6.3 10.4 8.5 5.9 5.9 5.6 9.5 5.1 5.4 6.8 1.9 6.2 9.2 3.0 5.6 5.6 3.5 4.1 5.0 4.8 3.8 3.8 4.2 4.7 4.6 3.8 4.2 5.7 5.6 0.0 4.8 11.1 5.8 12.1 7.6 7.5 8.0 2.9 5.9 5.0 6.8 7.2 7.3 0.0 0.0 9.2 3.9 3.9 9.8 10.1 10.7 7.7 7.1 6.9 3.6 10.7 12.5 11.8 10.0 6.5 8.2 12.7 3.8 7.8 3.9 8.1 9.2 3.3 11.1 4.6 4.1 6.0 5.4 7.3 5.0 6.1 3.6 10.3 8.0 7.6 3.1 12.1 18.7 8.4 3.8 5.7 10.4 5.6 5.3 7.2 4.8 4.9 19.7 7.0 7.0 44.4 17.5 9.4 12.5 10.5 5.9 6.9 6.4 5.8 ZWINT "KNTC2AP, SIP30, Zwint1" ENSG00000122952 "ZW10 interacting kinetochore protein" O95229 10 56357227-56361273 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.6;lymphoid tissue: 43.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 133.0;Extravillous trophoblasts: 108.6;Late spermatids: 208.8;Spermatocytes: 121.0;Spermatogonia: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 17.0" "Lineage enriched" "Detected in many" 5 "T-cells: 17.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA005757, HPA022264" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA005757: AB_10600224, HPA022264: AB_10600995" "unprognostic (5.59e-2)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-2)" "unprognostic (9.38e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.77e-8)" "unprognostic (6.36e-3)" "unprognostic (5.88e-2)" "unprognostic (1.45e-2)" "unprognostic (1.58e-3)" "unprognostic (1.86e-2)" "prognostic unfavorable (3.72e-12)" "unprognostic (1.40e-2)" "unprognostic (1.48e-1)" "unprognostic (5.47e-2)" "unprognostic (3.46e-1)" 2.6 2.5 1.2 15.7 1.3 41.6 6.5 1.1 1.8 3.9 1.0 18.8 13.7 3.2 1.7 12.4 2.8 2.4 1.5 1.5 1.2 4.4 4.8 2.9 26.5 1.2 1.3 1.5 2.4 5.4 0.8 10.8 1.2 2.5 22.4 0.5 3.3 1.4 0.3 10.8 14.8 6.8 1.2 5.0 12.5 26.1 1.6 43.5 3.9 0.7 33.0 5.0 4.3 1.4 199.8 154.8 107.9 120.9 7.5 10.8 88.1 143.1 108.0 169.6 153.4 275.4 116.1 102.0 53.2 49.6 79.1 99.9 153.2 108.3 156.7 259.9 80.2 101.6 120.8 129.4 0.7 169.6 131.0 5.1 6.8 157.7 64.9 20.8 86.8 134.2 140.2 121.4 151.1 160.1 150.7 108.3 77.0 135.9 188.7 151.7 209.5 54.0 53.5 87.5 99.8 61.2 135.2 304.2 35.3 62.2 197.3 163.4 47.4 73.6 189.4 76.9 223.2 105.8 55.3 176.0 103.8 210.0 94.7 0.0 0.8 0.7 2.4 3.0 0.3 1.6 5.3 3.6 1.4 0.3 6.3 3.6 0.0 3.5 2.3 1.1 17.0 3.1 1.2 1.3 1.1 1.8 1.5 1.2 1.2 1.3 1.2 1.2 1.6 1.4 0.9 3.2 1.7 0.3 11.1 18.4 6.0 20.2 4.6 2.0 9.4 5.5 1.4 2.8 7.3 5.5 0.0 73.7 3.3 17.9 0.0 9.7 74.0 7.0 4.3 5.7 0.0 133.0 1.3 13.3 108.6 10.3 16.8 8.0 0.0 27.6 7.9 3.5 49.4 0.0 0.3 22.8 14.2 8.5 8.8 208.8 5.0 9.2 7.2 0.0 2.6 1.3 0.0 0.0 0.6 8.6 16.4 2.6 42.4 1.9 8.7 6.0 2.5 0.9 0.0 1.4 10.6 121.0 100.3 24.5 8.2 23.1 7.9 6.5 39.4 8.4